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Sample records for lead 185

  1. Reliability of Sn/Pb and lead-free (SnAgCu) solders of surface mounted miniaturized passive components for extreme temperature (-185°C to +125°C) space missions

    NASA Astrophysics Data System (ADS)

    Ramesham, Rajeshuni

    2011-02-01

    Surface mount electronic package test boards have been assembled using tin/lead (Sn/Pb) and lead-free (Pb-free or SnAgCu or SAC305) solders. The soldered surface mount packages include ball grid arrays (BGA), flat packs, various sizes of passive chip components, etc. They have been optically inspected after assembly and subsequently subjected to extreme temperature thermal cycling to assess their reliability for future deep space, long-term, extreme temperature environmental missions. In this study, the employed temperature range (-185°C to +125°C) covers military specifications (-55°C to +100°C), extreme cold Martian (-120°C to +115°C), asteroid Nereus (-180°C to +25°C) and JUNO (-150°C to +120°C) environments. The boards were inspected at room temperature and at various intervals as a function of extreme temperature thermal cycling and bake duration. Electrical resistance measurements made at room temperature are reported and the tests to date have shown some change in resistance as a function of extreme temperature thermal cycling and some showed increase in resistance. However, the change in interconnect resistance becomes more noticeable with increasing number of thermal cycles. Further research work will be carried out to understand the reliability of packages under extreme temperature applications (-185°C to +125°C) via continuously monitoring the daisy chain resistance for BGA, Flat-packs, lead less chip packages, etc. This paper will describe the experimental reliability results of miniaturized passive components (01005, 0201, 0402, 0603, 0805, and 1206) assembled using surface mounting processes with tin-lead and lead-free solder alloys under extreme temperature environments.

  2. Reliability of Sn/Pb and Lead-Free (SnAgCu) Solders of Surface Mounted Miniaturized Passive Components for Extreme Temperature (-185 C to +125 C) Space Missions

    NASA Technical Reports Server (NTRS)

    Ramesham, Rajeshuni

    2011-01-01

    Surface mount electronic package test boards have been assembled using tin/lead (Sn/Pb) and lead-free (Pb-free or SnAgCu or SAC305) solders. The soldered surface mount packages include ball grid arrays (BGA), flat packs, various sizes of passive chip components, etc. They have been optically inspected after assembly and subsequently subjected to extreme temperature thermal cycling to assess their reliability or future deep space, long-term, extreme temperature environmental missions. In this study, the employed temperature range (-185oC to +125oC) covers military specifications (-55oC to +100oC), extreme old Martian (-120oC to +115oC), asteroid Nereus (-180oC to +25oC) and JUNO (-150oC to +120oC) environments. The boards were inspected at room temperature and at various intervals as a function of extreme temperature thermal cycling and bake duration. Electrical resistance measurements made at room temperature are reported and the tests to date have shown some change in resistance as a function of extreme temperature thermal cycling and some showed increase in resistance. However, the change in interconnect resistance becomes more noticeable with increasing number of thermal cycles. Further research work will be carried out to understand the reliability of packages under extreme temperature applications (-185oC to +125oC) via continuously monitoring the daisy chain resistance for BGA, Flat-packs, lead less chip packages, etc. This paper will describe the experimental reliability results of miniaturized passive components (01005, 0201, 0402, 0603, 0805, and 1206) assembled using surface mounting processes with tin-lead and lead-free solder alloys under extreme temperature environments.

  3. Lead

    MedlinePlus

    ... Lead Share Facebook Twitter Google+ Pinterest Contact Us Lead Poisoning is Preventable If your home was built before ... of the RRP rule. Read more . Learn about Lead Poisoning Prevention Week . Report Uncertified Contractors and Environmental Violations ...

  4. 32 CFR 185.6 - Information requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Information requirements. 185.6 Section 185.6 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE CIVIL DEFENSE MILITARY SUPPORT TO CIVIL AUTHORITIES (MSCA) § 185.6 Information requirements. The reporting requirements in § 185.5...

  5. Lead

    MedlinePlus

    ... obvious symptoms, it frequently goes unrecognized. CDC’s Childhood Lead Poisoning Prevention Program is committed to the Healthy People ... Lead Levels Information for Parents Tips for preventing lead poisoning About Us Overview of CDC’s Childhood Lead Poisoning ...

  6. 46 CFR 185.503 - Voyage plan.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Voyage plan. 185.503 Section 185.503 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Preparations for Emergencies § 185.503 Voyage plan. (a) The master of the following vessels...

  7. 46 CFR 185.503 - Voyage plan.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Voyage plan. 185.503 Section 185.503 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Preparations for Emergencies § 185.503 Voyage plan. (a) The master of the following vessels...

  8. 46 CFR 185.503 - Voyage plan.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Voyage plan. 185.503 Section 185.503 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Preparations for Emergencies § 185.503 Voyage plan. (a) The master of the following vessels...

  9. 46 CFR 185.503 - Voyage plan.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Voyage plan. 185.503 Section 185.503 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Preparations for Emergencies § 185.503 Voyage plan. (a) The master of the following vessels...

  10. 46 CFR 185.503 - Voyage plan.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Voyage plan. 185.503 Section 185.503 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Preparations for Emergencies § 185.503 Voyage plan. (a) The master of the following vessels...

  11. 46 CFR 185.304 - Navigation underway.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Navigation underway. 185.304 Section 185.304 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Miscellaneous Operating Requirements § 185.304 Navigation underway. (a) The movement of...

  12. 46 CFR 185.304 - Navigation underway.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Navigation underway. 185.304 Section 185.304 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Miscellaneous Operating Requirements § 185.304 Navigation underway. (a) The movement of...

  13. 46 CFR 185.304 - Navigation underway.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Navigation underway. 185.304 Section 185.304 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Miscellaneous Operating Requirements § 185.304 Navigation underway. (a) The movement of...

  14. 46 CFR 185.304 - Navigation underway.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Navigation underway. 185.304 Section 185.304 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Miscellaneous Operating Requirements § 185.304 Navigation underway. (a) The movement of...

  15. 5 CFR 185.142 - Judicial review.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Judicial review. 185.142 Section 185.142... § 185.142 Judicial review. Section 3805 of title 31, United States Code, authorizes judicial review by... penalties and/or assessments under this part and specifies the procedures for such review....

  16. 46 CFR 185.602 - Hull markings.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Hull markings. 185.602 Section 185.602 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Markings Required § 185.602 Hull markings. (a) Each vessel must be marked as required by part...

  17. 46 CFR 185.602 - Hull markings.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Hull markings. 185.602 Section 185.602 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Markings Required § 185.602 Hull markings. (a) Each vessel must be marked as required by part...

  18. 46 CFR 185.602 - Hull markings.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Hull markings. 185.602 Section 185.602 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Markings Required § 185.602 Hull markings. (a) Each vessel must be marked as required by part...

  19. 46 CFR 185.602 - Hull markings.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Hull markings. 185.602 Section 185.602 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Markings Required § 185.602 Hull markings. (a) Each vessel must be marked as required by part...

  20. 46 CFR 185.602 - Hull markings.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Hull markings. 185.602 Section 185.602 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Markings Required § 185.602 Hull markings. (a) Each vessel must be marked as required by part...

  1. 32 CFR 185.5 - Responsibilities.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Responsibilities. 185.5 Section 185.5 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE CIVIL DEFENSE MILITARY SUPPORT TO CIVIL AUTHORITIES (MSCA) § 185.5 Responsibilities. (a) The Under Secretary of Defense For Policy shall: (1) Exercise policy oversight of MSCA for...

  2. 32 CFR 18.5 - Relationships.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Relationships. 18.5 Section 18.5 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE MILITARY COMMISSIONS APPOINTING AUTHORITY FOR MILITARY COMMISSIONS § 18.5 Relationships. (a) In the performance of assigned functions...

  3. 32 CFR 18.5 - Relationships.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 1 2011-07-01 2011-07-01 false Relationships. 18.5 Section 18.5 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE MILITARY COMMISSIONS APPOINTING AUTHORITY FOR MILITARY COMMISSIONS § 18.5 Relationships. (a) In the performance of assigned functions...

  4. 5 CFR 185.122 - Discovery.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 1 2012-01-01 2012-01-01 false Discovery. 185.122 Section 185.122... § 185.122 Discovery. (a) The following types of discovery are authorized: (1) Requests for production of..., discovery is available only as ordered by the ALJ. The ALJ shall regulate the timing of discovery....

  5. 5 CFR 185.122 - Discovery.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Discovery. 185.122 Section 185.122... § 185.122 Discovery. (a) The following types of discovery are authorized: (1) Requests for production of..., discovery is available only as ordered by the ALJ. The ALJ shall regulate the timing of discovery....

  6. 5 CFR 185.122 - Discovery.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Discovery. 185.122 Section 185.122... § 185.122 Discovery. (a) The following types of discovery are authorized: (1) Requests for production of..., discovery is available only as ordered by the ALJ. The ALJ shall regulate the timing of discovery....

  7. 5 CFR 185.122 - Discovery.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Discovery. 185.122 Section 185.122 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.122 Discovery. (a) The following types of discovery are authorized: (1) Requests for production of documents for inspection and copying;...

  8. 40 CFR 68.185 - Certification.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 16 2012-07-01 2012-07-01 false Certification. 68.185 Section 68.185 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CHEMICAL ACCIDENT PREVENTION PROVISIONS Risk Management Plan § 68.185 Certification. (a) For Program 1...

  9. 40 CFR 68.185 - Certification.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 16 2013-07-01 2013-07-01 false Certification. 68.185 Section 68.185 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CHEMICAL ACCIDENT PREVENTION PROVISIONS Risk Management Plan § 68.185 Certification. (a) For Program 1...

  10. 40 CFR 68.185 - Certification.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 16 2014-07-01 2014-07-01 false Certification. 68.185 Section 68.185 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CHEMICAL ACCIDENT PREVENTION PROVISIONS Risk Management Plan § 68.185 Certification. (a) For Program 1...

  11. 21 CFR 172.185 - TBHQ.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 3 2014-04-01 2014-04-01 false TBHQ. 172.185 Section 172.185 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION Food Preservatives § 172.185 TBHQ. The food additive TBHQ, which is the chemical...

  12. 21 CFR 172.185 - TBHQ.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 3 2011-04-01 2011-04-01 false TBHQ. 172.185 Section 172.185 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION Food Preservatives § 172.185 TBHQ. The food additive...

  13. 5 CFR 185.125 - Protective order.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Protective order. 185.125 Section 185.125 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.125 Protective order. (a) A party or a prospective witness or deponent may file a motion for...

  14. 5 CFR 185.104 - Investigation.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Investigation. 185.104 Section 185.104... § 185.104 Investigation. (a) If an investigating official concludes that a subpoena pursuant to the... submit a report containing the findings and conclusions of such investigation to the reviewing...

  15. 5 CFR 185.104 - Investigation.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Investigation. 185.104 Section 185.104... § 185.104 Investigation. (a) If an investigating official concludes that a subpoena pursuant to the... submit a report containing the findings and conclusions of such investigation to the reviewing...

  16. 46 CFR 185.514 - Station bill.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Station bill. 185.514 Section 185.514 Shipping COAST...) OPERATIONS Preparations for Emergencies § 185.514 Station bill. (a) A station bill must be posted by the... requiring more than four crew members at any one time, including the master. (b) The station bill...

  17. 46 CFR 185.514 - Station bill.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Station bill. 185.514 Section 185.514 Shipping COAST...) OPERATIONS Preparations for Emergencies § 185.514 Station bill. (a) A station bill must be posted by the... requiring more than four crew members at any one time, including the master. (b) The station bill...

  18. 46 CFR 185.514 - Station bill.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Station bill. 185.514 Section 185.514 Shipping COAST...) OPERATIONS Preparations for Emergencies § 185.514 Station bill. (a) A station bill must be posted by the... requiring more than four crew members at any one time, including the master. (b) The station bill...

  19. 46 CFR 185.514 - Station bill.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Station bill. 185.514 Section 185.514 Shipping COAST...) OPERATIONS Preparations for Emergencies § 185.514 Station bill. (a) A station bill must be posted by the... requiring more than four crew members at any one time, including the master. (b) The station bill...

  20. 46 CFR 185.514 - Station bill.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Station bill. 185.514 Section 185.514 Shipping COAST...) OPERATIONS Preparations for Emergencies § 185.514 Station bill. (a) A station bill must be posted by the... requiring more than four crew members at any one time, including the master. (b) The station bill...

  1. 46 CFR 45.185 - Tow limitations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Tow limitations. 45.185 Section 45.185 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) LOAD LINES GREAT LAKES LOAD LINES Unmanned River Barges on Lake Michigan Routes § 45.185 Tow limitations. (a) Barges must not be manned. (b) No more...

  2. 46 CFR 45.185 - Tow limitations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Tow limitations. 45.185 Section 45.185 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) LOAD LINES GREAT LAKES LOAD LINES Unmanned River Barges on Lake Michigan Routes § 45.185 Tow limitations. (a) Barges must not be manned. (b) No more...

  3. 46 CFR 45.185 - Tow limitations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Tow limitations. 45.185 Section 45.185 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) LOAD LINES GREAT LAKES LOAD LINES Unmanned River Barges on Lake Michigan Routes § 45.185 Tow limitations. (a) Barges must not be manned. (b) No more...

  4. 46 CFR 45.185 - Tow limitations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Tow limitations. 45.185 Section 45.185 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) LOAD LINES GREAT LAKES LOAD LINES Unmanned River Barges on Lake Michigan Routes § 45.185 Tow limitations. (a) Barges must not be manned. (b) No more...

  5. 46 CFR 45.185 - Tow limitations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Tow limitations. 45.185 Section 45.185 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) LOAD LINES GREAT LAKES LOAD LINES Unmanned River Barges on Lake Michigan Routes § 45.185 Tow limitations. (a) Barges must not be manned. (b) No more...

  6. 21 CFR 146.185 - Pineapple juice.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Pineapple juice. 146.185 Section 146.185 Food and....185 Pineapple juice. (a) Identity. (1) Pineapple juice is the juice, intended for direct consumption..., ripe pineapple (Ananas comosus L. Merrill). The juice may have been concentrated and...

  7. 21 CFR 146.185 - Pineapple juice.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 2 2013-04-01 2013-04-01 false Pineapple juice. 146.185 Section 146.185 Food and....185 Pineapple juice. (a) Identity. (1) Pineapple juice is the juice, intended for direct consumption..., ripe pineapple (Ananas comosus L. Merrill). The juice may have been concentrated and...

  8. 21 CFR 146.185 - Pineapple juice.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 2 2011-04-01 2011-04-01 false Pineapple juice. 146.185 Section 146.185 Food and....185 Pineapple juice. (a) Identity. (1) Pineapple juice is the juice, intended for direct consumption..., ripe pineapple (Ananas comosus L. Merrill). The juice may have been concentrated and...

  9. 21 CFR 146.185 - Pineapple juice.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 2 2014-04-01 2014-04-01 false Pineapple juice. 146.185 Section 146.185 Food and....185 Pineapple juice. (a) Identity. (1) Pineapple juice is the juice, intended for direct consumption..., ripe pineapple (Ananas comosus L. Merrill). The juice may have been concentrated and...

  10. 21 CFR 146.185 - Pineapple juice.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 2 2012-04-01 2012-04-01 false Pineapple juice. 146.185 Section 146.185 Food and....185 Pineapple juice. (a) Identity. (1) Pineapple juice is the juice, intended for direct consumption..., ripe pineapple (Ananas comosus L. Merrill). The juice may have been concentrated and...

  11. 5 CFR 185.135 - The record.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false The record. 185.135 Section 185.135... § 185.135 The record. (a) The hearing shall be recorded and transcribed. Transcripts may be obtained following the hearing from the ALJ at a cost not to exceed the actual cost of duplication. (b)...

  12. 5 CFR 185.135 - The record.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false The record. 185.135 Section 185.135... § 185.135 The record. (a) The hearing shall be recorded and transcribed. Transcripts may be obtained following the hearing from the ALJ at a cost not to exceed the actual cost of duplication. (b)...

  13. 5 CFR 185.135 - The record.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false The record. 185.135 Section 185.135... § 185.135 The record. (a) The hearing shall be recorded and transcribed. Transcripts may be obtained following the hearing from the ALJ at a cost not to exceed the actual cost of duplication. (b)...

  14. 5 CFR 185.135 - The record.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false The record. 185.135 Section 185.135... § 185.135 The record. (a) The hearing shall be recorded and transcribed. Transcripts may be obtained following the hearing from the ALJ at a cost not to exceed the actual cost of duplication. (b)...

  15. 5 CFR 185.135 - The record.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 1 2012-01-01 2012-01-01 false The record. 185.135 Section 185.135... § 185.135 The record. (a) The hearing shall be recorded and transcribed. Transcripts may be obtained following the hearing from the ALJ at a cost not to exceed the actual cost of duplication. (b)...

  16. 40 CFR 185.4400 - Nitrogen.

    Code of Federal Regulations, 2012 CFR

    1996-07-01

    ... 40 PROTECTION OF ENVIRONMENT 11 1996-07-01 1996-07-01 false Nitrogen. 185.4400 Sec. 185.4400... PESTICIDES IN FOOD Food Additives Permitted in Food for Human Consumption Sec. 185.4400 Nitrogen. The food additive nitrogen may be safely used after harvest in modified atmospheres for stored product...

  17. 40 CFR 185.4400 - Nitrogen.

    Code of Federal Regulations, 2013 CFR

    1997-07-01

    ... 40 Protection of Environment 14 1997-07-01 1997-07-01 false Nitrogen. 185.4400 Section 185.4400 PESTICIDE PROGRAMS TOLERANCES FOR PESTICIDES IN FOOD Food Additives Permitted in Food for Human Consumption § 185.4400 Nitrogen. The food additive nitrogen may be safely used after harvest in modified...

  18. 40 CFR 185.4400 - Nitrogen.

    Code of Federal Regulations, 2014 CFR

    1999-07-01

    ... 40 Protection of Environment 16 1999-07-01 1999-07-01 false Nitrogen. 185.4400 Section 185.4400... PESTICIDES IN FOOD Food Additives Permitted in Food for Human Consumption § 185.4400 Nitrogen. The food additive nitrogen may be safely used after harvest in modified atmospheres for stored product...

  19. 40 CFR 185.4400 - Nitrogen.

    Code of Federal Regulations, 2014 CFR

    1998-07-01

    ... 40 Protection of Environment 15 1998-07-01 1998-07-01 false Nitrogen. 185.4400 Section 185.4400 PESTICIDE PROGRAMS TOLERANCES FOR PESTICIDES IN FOOD Food Additives Permitted in Food for Human Consumption § 185.4400 Nitrogen. The food additive nitrogen may be safely used after harvest in modified...

  20. 46 CFR 185.510 - Emergency instructions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Emergency instructions. 185.510 Section 185.510 Shipping...) OPERATIONS Preparations for Emergencies § 185.510 Emergency instructions. (a) The master and crew of a vessel will be familiar with the content of and have mounted at the operating station, emergency...

  1. 5 CFR 185.142 - Judicial review.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 1 2012-01-01 2012-01-01 false Judicial review. 185.142 Section 185.142... § 185.142 Judicial review. Section 3805 of title 31, United States Code, authorizes judicial review by... penalties and/or assessments under this part and specifies the procedures for such review....

  2. 5 CFR 185.125 - Protective order.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Protective order. 185.125 Section 185.125... § 185.125 Protective order. (a) A party or a prospective witness or deponent may file a motion for a protective order with respect to discovery sought by an opposing party or with respect to the...

  3. 5 CFR 185.107 - Complaint.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Complaint. 185.107 Section 185.107 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.107 Complaint. (a) On or after the date the Department of Justice approves the issuance of...

  4. 5 CFR 185.109 - Answer.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Answer. 185.109 Section 185.109 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.109 Answer. (a) The defendant may request a hearing in the answer filed with the...

  5. 5 CFR 185.131 - Sanctions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Sanctions. 185.131 Section 185.131 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.131 Sanctions. (a) The ALJ may sanction a person including any party or representative for...

  6. 5 CFR 185.127 - Fees.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Fees. 185.127 Section 185.127 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.127 Fees. The party requesting a subpoena shall pay the cost of the fees and mileage of...

  7. 5 CFR 185.137 - Initial decision.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Initial decision. 185.137 Section 185.137 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.137 Initial decision. (a) The ALJ shall issue an initial decision based only on the record,...

  8. 5 CFR 185.147 - Limitations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Limitations. 185.147 Section 185.147 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.147 Limitations. (a) The notice of hearing with respect to a claim or statement must be served...

  9. 5 CFR 185.126 - Evidence.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Evidence. 185.126 Section 185.126 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.126 Evidence. (a) The ALJ shall determine the admissibility of evidence. (b) Except as provided...

  10. 5 CFR 185.142 - Judicial review.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Judicial review. 185.142 Section 185.142 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.142 Judicial review. Section 3805 of title 31, United States Code, authorizes judicial review...

  11. 5 CFR 185.102 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Definitions. 185.102 Section 185.102 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.102 Definitions. For the purposes of this part— ALJ means an Administrative Law Judge in...

  12. 46 CFR 185.335 - Loading doors.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Loading doors. 185.335 Section 185.335 Shipping COAST...) OPERATIONS Miscellaneous Operating Requirements § 185.335 Loading doors. (a) Except as allowed by paragraph (b) of this section, the master of a vessel fitted with loading doors shall assure that all...

  13. 46 CFR 185.335 - Loading doors.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Loading doors. 185.335 Section 185.335 Shipping COAST...) OPERATIONS Miscellaneous Operating Requirements § 185.335 Loading doors. (a) Except as allowed by paragraph (b) of this section, the master of a vessel fitted with loading doors shall assure that all...

  14. 46 CFR 185.335 - Loading doors.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Loading doors. 185.335 Section 185.335 Shipping COAST...) OPERATIONS Miscellaneous Operating Requirements § 185.335 Loading doors. (a) Except as allowed by paragraph (b) of this section, the master of a vessel fitted with loading doors shall assure that all...

  15. 46 CFR 185.335 - Loading doors.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Loading doors. 185.335 Section 185.335 Shipping COAST...) OPERATIONS Miscellaneous Operating Requirements § 185.335 Loading doors. (a) Except as allowed by paragraph (b) of this section, the master of a vessel fitted with loading doors shall assure that all...

  16. 46 CFR 185.335 - Loading doors.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Loading doors. 185.335 Section 185.335 Shipping COAST...) OPERATIONS Miscellaneous Operating Requirements § 185.335 Loading doors. (a) Except as allowed by paragraph (b) of this section, the master of a vessel fitted with loading doors shall assure that all...

  17. 46 CFR 185.410 - Watchmen.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Watchmen. 185.410 Section 185.410 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Crew Requirements § 185.410 Watchmen. The owner, charterer, master, or managing operator of a vessel...

  18. 46 CFR 185.510 - Emergency instructions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Emergency instructions. 185.510 Section 185.510 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Preparations for Emergencies § 185.510 Emergency instructions. (a) The master and crew of a...

  19. 5 CFR 185.130 - Motions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Motions. 185.130 Section 185.130... § 185.130 Motions. (a) Any application to the ALJ for an order or ruling shall be by motion. Motions... the ALJ and served on all other parties. (b) Except for motions made during a prehearing conference...

  20. 5 CFR 185.130 - Motions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 1 2012-01-01 2012-01-01 false Motions. 185.130 Section 185.130... § 185.130 Motions. (a) Any application to the ALJ for an order or ruling shall be by motion. Motions... the ALJ and served on all other parties. (b) Except for motions made during a prehearing conference...

  1. 5 CFR 185.130 - Motions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Motions. 185.130 Section 185.130... § 185.130 Motions. (a) Any application to the ALJ for an order or ruling shall be by motion. Motions... the ALJ and served on all other parties. (b) Except for motions made during a prehearing conference...

  2. 5 CFR 185.130 - Motions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Motions. 185.130 Section 185.130... § 185.130 Motions. (a) Any application to the ALJ for an order or ruling shall be by motion. Motions... the ALJ and served on all other parties. (b) Except for motions made during a prehearing conference...

  3. 5 CFR 185.130 - Motions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Motions. 185.130 Section 185.130... § 185.130 Motions. (a) Any application to the ALJ for an order or ruling shall be by motion. Motions... the ALJ and served on all other parties. (b) Except for motions made during a prehearing conference...

  4. 21 CFR 172.185 - TBHQ.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 3 2010-04-01 2009-04-01 true TBHQ. 172.185 Section 172.185 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION Food Preservatives § 172.185 TBHQ. The food additive...

  5. 40 CFR 98.185 - Procedures for estimating missing data.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Procedures for estimating missing data... PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Lead Production § 98.185 Procedures for estimating... such estimates. (a) For each missing data for the carbon content for the smelting furnaces at...

  6. 14 CFR 61.185 - Aeronautical knowledge.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Aeronautical knowledge. 61.185 Section 61... Flight Instructors With a Sport Pilot Rating § 61.185 Aeronautical knowledge. (a) A person who is... aeronautical knowledge areas for a recreational, private, and commercial pilot certificate applicable to...

  7. 27 CFR 27.185 - Customs release.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Customs release. 27.185... Distilled Spirits From Customs Custody Free of Tax for Use of the United States § 27.185 Customs release. (a) Upon receipt of appropriate customs entry and a photocopy of a permit, Form 5150.33 or...

  8. 27 CFR 27.185 - Customs release.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2013-04-01 2013-04-01 false Customs release. 27.185... Distilled Spirits From Customs Custody Free of Tax for Use of the United States § 27.185 Customs release. (a) Upon receipt of appropriate customs entry and a photocopy of a permit, Form 5150.33 or...

  9. 27 CFR 27.185 - Customs release.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2012-04-01 2012-04-01 false Customs release. 27.185... Distilled Spirits From Customs Custody Free of Tax for Use of the United States § 27.185 Customs release. (a) Upon receipt of appropriate customs entry and a photocopy of a permit, Form 5150.33 or...

  10. 5 CFR 185.125 - Protective order.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Protective order. 185.125 Section 185.125 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES... be opened only by order of the ALJ; (8) That a trade secret or other confidential...

  11. 5 CFR 185.125 - Protective order.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 1 2012-01-01 2012-01-01 false Protective order. 185.125 Section 185.125 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES... be opened only by order of the ALJ; (8) That a trade secret or other confidential...

  12. 5 CFR 185.120 - Prehearing conferences.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Prehearing conferences. 185.120 Section 185.120 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM... hearing and to submit only documentary evidence (subject to the objection of other parties) and...

  13. 5 CFR 185.122 - Discovery.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Discovery. 185.122 Section 185.122 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES..., answers, records, accounts, papers, and other data and documentary evidence. Nothing contained...

  14. 27 CFR 27.185 - Customs release.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Customs release. 27.185... Distilled Spirits From Customs Custody Free of Tax for Use of the United States § 27.185 Customs release. (a) Upon receipt of appropriate customs entry and a photocopy of a permit, Form 5150.33 or...

  15. 27 CFR 27.185 - Customs release.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2014-04-01 2014-04-01 false Customs release. 27.185... Distilled Spirits From Customs Custody Free of Tax for Use of the United States § 27.185 Customs release. (a) Upon receipt of appropriate customs entry and a photocopy of a permit, Form 5150.33 or...

  16. 14 CFR 61.185 - Aeronautical knowledge.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 2 2012-01-01 2012-01-01 false Aeronautical knowledge. 61.185 Section 61... Flight Instructors With a Sport Pilot Rating § 61.185 Aeronautical knowledge. (a) A person who is... aeronautical knowledge areas for a recreational, private, and commercial pilot certificate applicable to...

  17. 14 CFR 61.185 - Aeronautical knowledge.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 2 2013-01-01 2013-01-01 false Aeronautical knowledge. 61.185 Section 61... Flight Instructors With a Sport Pilot Rating § 61.185 Aeronautical knowledge. (a) A person who is... aeronautical knowledge areas for a recreational, private, and commercial pilot certificate applicable to...

  18. 14 CFR 61.185 - Aeronautical knowledge.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 2 2014-01-01 2014-01-01 false Aeronautical knowledge. 61.185 Section 61... Flight Instructors With a Sport Pilot Rating § 61.185 Aeronautical knowledge. (a) A person who is... aeronautical knowledge areas for a recreational, private, and commercial pilot certificate applicable to...

  19. 14 CFR 61.185 - Aeronautical knowledge.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 2 2011-01-01 2011-01-01 false Aeronautical knowledge. 61.185 Section 61... Flight Instructors With a Sport Pilot Rating § 61.185 Aeronautical knowledge. (a) A person who is... aeronautical knowledge areas for a recreational, private, and commercial pilot certificate applicable to...

  20. 21 CFR 172.185 - TBHQ.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... exceed 0.02 percent of the oil or fat content of the food, including the essential (volatile) oil content... 21 Food and Drugs 3 2013-04-01 2013-04-01 false TBHQ. 172.185 Section 172.185 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR...

  1. 27 CFR 555.185 - Criminal sanctions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 3 2010-04-01 2010-04-01 false Criminal sanctions. 555.185 Section 555.185 Alcohol, Tobacco Products, and Firearms BUREAU OF ALCOHOL, TOBACCO, FIREARMS, AND... Criminal sanctions. Any person who violates the provisions of 18 U.S.C. 842(l)-(o) shall be fined...

  2. 27 CFR 555.185 - Criminal sanctions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 3 2011-04-01 2010-04-01 true Criminal sanctions. 555.185 Section 555.185 Alcohol, Tobacco Products, and Firearms BUREAU OF ALCOHOL, TOBACCO, FIREARMS, AND... Criminal sanctions. Any person who violates the provisions of 18 U.S.C. 842(l)-(o) shall be fined...

  3. 27 CFR 555.185 - Criminal sanctions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 3 2014-04-01 2014-04-01 false Criminal sanctions. 555.185 Section 555.185 Alcohol, Tobacco Products, and Firearms BUREAU OF ALCOHOL, TOBACCO, FIREARMS, AND... Criminal sanctions. Any person who violates the provisions of 18 U.S.C. 842(l)-(o) shall be fined...

  4. 27 CFR 555.185 - Criminal sanctions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 3 2013-04-01 2013-04-01 false Criminal sanctions. 555.185 Section 555.185 Alcohol, Tobacco Products, and Firearms BUREAU OF ALCOHOL, TOBACCO, FIREARMS, AND... Criminal sanctions. Any person who violates the provisions of 18 U.S.C. 842(l)-(o) shall be fined...

  5. 27 CFR 555.185 - Criminal sanctions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 3 2012-04-01 2010-04-01 true Criminal sanctions. 555.185 Section 555.185 Alcohol, Tobacco Products, and Firearms BUREAU OF ALCOHOL, TOBACCO, FIREARMS, AND... Criminal sanctions. Any person who violates the provisions of 18 U.S.C. 842(l)-(o) shall be fined...

  6. 49 CFR 192.185 - Vaults: Accessibility.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Vaults: Accessibility. 192.185 Section 192.185 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY...: Accessibility. Each vault must be located in an accessible location and, so far as practical, away from:...

  7. 7 CFR 65.185 - Ingredient.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Ingredient. 65.185 Section 65.185 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 AND THE...

  8. 7 CFR 65.185 - Ingredient.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 3 2014-01-01 2014-01-01 false Ingredient. 65.185 Section 65.185 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 AND THE...

  9. 7 CFR 65.185 - Ingredient.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 3 2011-01-01 2011-01-01 false Ingredient. 65.185 Section 65.185 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 AND THE...

  10. 7 CFR 65.185 - Ingredient.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 3 2013-01-01 2013-01-01 false Ingredient. 65.185 Section 65.185 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 AND THE...

  11. 7 CFR 65.185 - Ingredient.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 3 2012-01-01 2012-01-01 false Ingredient. 65.185 Section 65.185 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 AND THE...

  12. 5 CFR 185.125 - Protective order.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Protective order. 185.125 Section 185.125 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES... administrative investigation not be disclosed or be disclosed only in a designated way; or (9) That the...

  13. 5 CFR 185.101 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Purpose. 185.101 Section 185.101 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES.... The subpart establishes administrative procedures for imposing civil penalties and assessments...

  14. 15 CFR 922.185 - Emergency regulations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false Emergency regulations. 922.185 Section... Sanctuary § 922.185 Emergency regulations. Where necessary to prevent or minimize the destruction of, loss... relevant Federal agency and the Governor of the State of Hawaii. Emergency regulations shall not...

  15. 40 CFR 68.185 - Certification.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... certification that, to the best of the signer's knowledge, information, and belief formed after reasonable inquiry, the information submitted is true, accurate, and complete. ... ACCIDENT PREVENTION PROVISIONS Risk Management Plan § 68.185 Certification. (a) For Program 1...

  16. 40 CFR 68.185 - Certification.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... ACCIDENT PREVENTION PROVISIONS Risk Management Plan § 68.185 Certification. (a) For Program 1 processes... certification that, to the best of the signer's knowledge, information, and belief formed after...

  17. miR-185 inhibits hepatocellular carcinoma growth by targeting the DNMT1/PTEN/Akt pathway.

    PubMed

    Qadir, Ximena V; Han, Chang; Lu, Dongdong; Zhang, Jinqiang; Wu, Tong

    2014-08-01

    miRNAs have recently been implicated in hepatocarcinogenesis, although the actions and mechanisms of individual miRNAs remain incompletely understood. We examined the biological functions and molecular mechanisms of miR-185 in hepatocellular carcinoma (HCC). The expression of miR-185 is decreased in human HCC tissues compared with the nonneoplastic liver parenchyma. Quantitative RT-PCR showed a reduction of miR-185 in human HCC cells compared with primary hepatocytes. miR-185 overexpression in human HCC cells inhibited cell proliferation and invasion in vitro and prevented tumor growth in SCID mice. miR-185 overexpression inhibited DNMT1 3' untranslated region luciferase reporter activity in HCC cells; this effect was abolished when the miR-185 binding site was mutated. miR-185 mimic or overexpression decreased the level of DNMT1 protein in HCC cells. These findings establish DNMT1 as a bona fide target of miR-185 in HCC cells. The role of DNMT1 in miR-185-induced inhibition of HCC growth was further supported by the fact that DNMT1 overexpression prevented miR-185-induced inhibition of HCC cell proliferation/invasion. miR-185 mimic or overexpression reduced PTEN promoter DNA methylation and enhanced PTEN expression, leading to the inhibition of Akt phosphorylation; these effects were partially reversed by DNMT1 overexpression. These results provide novel evidence that miR-185 inhibits HCC cell growth by targeting DNMT1, leading to PTEN induction and Akt inhibition. Thus, reactivation or induction of miR-185 may represent a novel therapeutic strategy for HCC treatment. PMID:24911372

  18. miR-185 Inhibits Hepatocellular Carcinoma Growth by Targeting the DNMT1/PTEN/Akt Pathway

    PubMed Central

    Qadir, Ximena V.; Han, Chang; Lu, Dongdong; Zhang, Jinqiang; Wu, Tong

    2015-01-01

    miRNAs have recently been implicated in hepatocarcinogenesis, although the actions and mechanisms of individual miRNAs remain incompletely understood. We examined the biological functions and molecular mechanisms of miR-185 in hepatocellular carcinoma (HCC). The expression of miR-185 is decreased in human HCC tissues compared with the nonneoplastic liver parenchyma. Quantitative RT-PCR showed a reduction of miR-185 in human HCC cells compared with primary hepatocytes. miR-185 overexpression in human HCC cells inhibited cell proliferation and invasion in vitro and prevented tumor growth in SCID mice. miR-185 overexpression inhibited DNMT1 3′ untranslated region luciferase reporter activity in HCC cells; this effect was abolished when the miR-185 binding site was mutated. miR-185 mimic or overexpression decreased the level of DNMT1 protein in HCC cells. These findings establish DNMT1 as a bona fide target of miR-185 in HCC cells. The role of DNMT1 in miR-185–induced inhibition of HCC growth was further supported by the fact that DNMT1 overexpression prevented miR-185–induced inhibition of HCC cell proliferation/invasion. miR-185 mimic or overexpression reduced PTEN promoter DNA methylation and enhanced PTEN expression, leading to the inhibition of Akt phosphorylation; these effects were partially reversed by DNMT1 overexpression. These results provide novel evidence that miR-185 inhibits HCC cell growth by targeting DNMT1, leading to PTEN induction and Akt inhibition. Thus, reactivation or induction of miR-185 may represent a novel therapeutic strategy for HCC treatment. PMID:24911372

  19. 5 CFR 185.134 - Witnesses.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... § 185.134 Witnesses. (a) Except as provided in paragraph (b) of this section, testimony at the hearing..., testimony may be admitted in the form of a written statement or deposition. Any such written statement must be provided to all others parties along with the last known address of such witness, in a...

  20. 28 CFR 18.5 - Hearings.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Administration DEPARTMENT OF JUSTICE OFFICE OF JUSTICE PROGRAMS HEARING AND APPEAL PROCEDURES § 18.5 Hearings. (a... inform the party of the reasons for the agency's proposed action; (2) A statement of the nature of the action proposed to be taken; and (3) A reference of the available appeal rights. (c) If a block...

  1. 28 CFR 18.5 - Hearings.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Administration DEPARTMENT OF JUSTICE OFFICE OF JUSTICE PROGRAMS HEARING AND APPEAL PROCEDURES § 18.5 Hearings. (a... inform the party of the reasons for the agency's proposed action; (2) A statement of the nature of the action proposed to be taken; and (3) A reference of the available appeal rights. (c) If a block...

  2. 28 CFR 18.5 - Hearings.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Administration DEPARTMENT OF JUSTICE OFFICE OF JUSTICE PROGRAMS HEARING AND APPEAL PROCEDURES § 18.5 Hearings. (a... inform the party of the reasons for the agency's proposed action; (2) A statement of the nature of the action proposed to be taken; and (3) A reference of the available appeal rights. (c) If a block...

  3. 28 CFR 18.5 - Hearings.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Administration DEPARTMENT OF JUSTICE OFFICE OF JUSTICE PROGRAMS HEARING AND APPEAL PROCEDURES § 18.5 Hearings. (a... inform the party of the reasons for the agency's proposed action; (2) A statement of the nature of the action proposed to be taken; and (3) A reference of the available appeal rights. (c) If a block...

  4. 28 CFR 18.5 - Hearings.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Administration DEPARTMENT OF JUSTICE OFFICE OF JUSTICE PROGRAMS HEARING AND APPEAL PROCEDURES § 18.5 Hearings. (a... inform the party of the reasons for the agency's proposed action; (2) A statement of the nature of the action proposed to be taken; and (3) A reference of the available appeal rights. (c) If a block...

  5. 27 CFR 25.185 - Mingling.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... THE TREASURY ALCOHOL BEER Removals Without Payment of Tax Transfer to Another Brewery of Same Ownership § 25.185 Mingling. Beer transferred without payment of tax from one brewery to another brewery belonging to the same brewer may be mingled with beer of the receiving brewery. The brewer may handle...

  6. 27 CFR 25.185 - Mingling.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... THE TREASURY LIQUORS BEER Removals Without Payment of Tax Transfer to Another Brewery of Same Ownership § 25.185 Mingling. Beer transferred without payment of tax from one brewery to another brewery belonging to the same brewer may be mingled with beer of the receiving brewery. The brewer may handle...

  7. 27 CFR 25.185 - Mingling.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... THE TREASURY LIQUORS BEER Removals Without Payment of Tax Transfer to Another Brewery of Same Ownership § 25.185 Mingling. Beer transferred without payment of tax from one brewery to another brewery belonging to the same brewer may be mingled with beer of the receiving brewery. The brewer may handle...

  8. 27 CFR 25.185 - Mingling.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... THE TREASURY ALCOHOL BEER Removals Without Payment of Tax Transfer to Another Brewery of Same Ownership § 25.185 Mingling. Beer transferred without payment of tax from one brewery to another brewery belonging to the same brewer may be mingled with beer of the receiving brewery. The brewer may handle...

  9. 27 CFR 25.185 - Mingling.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... THE TREASURY LIQUORS BEER Removals Without Payment of Tax Transfer to Another Brewery of Same Ownership § 25.185 Mingling. Beer transferred without payment of tax from one brewery to another brewery belonging to the same brewer may be mingled with beer of the receiving brewery. The brewer may handle...

  10. 40 CFR 61.185 - Recordkeeping requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Arsenic Emissions From Arsenic Trioxide and Metallic Arsenic Production Facilities § 61.185 Recordkeeping... arsenic to the atmosphere between the time of discovery and the time corrective action was taken. (c) Each... ambient inorganic arsenic concentrations at all sampling sites and other data needed to determine...

  11. 40 CFR 61.185 - Recordkeeping requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Arsenic Emissions From Arsenic Trioxide and Metallic Arsenic Production Facilities § 61.185 Recordkeeping... arsenic to the atmosphere between the time of discovery and the time corrective action was taken. (c) Each... ambient inorganic arsenic concentrations at all sampling sites and other data needed to determine...

  12. 40 CFR 61.185 - Recordkeeping requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Arsenic Emissions From Arsenic Trioxide and Metallic Arsenic Production Facilities § 61.185 Recordkeeping... arsenic to the atmosphere between the time of discovery and the time corrective action was taken. (c) Each... ambient inorganic arsenic concentrations at all sampling sites and other data needed to determine...

  13. 40 CFR 61.185 - Recordkeeping requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Arsenic Emissions From Arsenic Trioxide and Metallic Arsenic Production Facilities § 61.185 Recordkeeping... arsenic to the atmosphere between the time of discovery and the time corrective action was taken. (c) Each... ambient inorganic arsenic concentrations at all sampling sites and other data needed to determine...

  14. 40 CFR 61.185 - Recordkeeping requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Arsenic Emissions From Arsenic Trioxide and Metallic Arsenic Production Facilities § 61.185 Recordkeeping... arsenic to the atmosphere between the time of discovery and the time corrective action was taken. (c) Each... ambient inorganic arsenic concentrations at all sampling sites and other data needed to determine...

  15. 21 CFR 73.185 - Haematococcus algae meal.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 1 2013-04-01 2013-04-01 false Haematococcus algae meal. 73.185 Section 73.185... COLOR ADDITIVES EXEMPT FROM CERTIFICATION Foods § 73.185 Haematococcus algae meal. (a) Identity. (1) The color additive haematococcus algae meal consists of the comminuted and dried cells of the...

  16. 21 CFR 73.185 - Haematococcus algae meal.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 1 2014-04-01 2014-04-01 false Haematococcus algae meal. 73.185 Section 73.185... COLOR ADDITIVES EXEMPT FROM CERTIFICATION Foods § 73.185 Haematococcus algae meal. (a) Identity. (1) The color additive haematococcus algae meal consists of the comminuted and dried cells of the...

  17. 21 CFR 73.185 - Haematococcus algae meal.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Haematococcus algae meal. 73.185 Section 73.185... COLOR ADDITIVES EXEMPT FROM CERTIFICATION Foods § 73.185 Haematococcus algae meal. (a) Identity. (1) The color additive haematococcus algae meal consists of the comminuted and dried cells of the...

  18. 46 CFR 185.502 - Crew and passenger list.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Crew and passenger list. 185.502 Section 185.502 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Preparations for Emergencies § 185.502 Crew and passenger list. (a) The...

  19. 46 CFR 185.502 - Crew and passenger list.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Crew and passenger list. 185.502 Section 185.502 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Preparations for Emergencies § 185.502 Crew and passenger list. (a) The...

  20. 46 CFR 185.502 - Crew and passenger list.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Crew and passenger list. 185.502 Section 185.502 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Preparations for Emergencies § 185.502 Crew and passenger list. (a) The...

  1. 46 CFR 185.502 - Crew and passenger list.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Crew and passenger list. 185.502 Section 185.502 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Preparations for Emergencies § 185.502 Crew and passenger list. (a) The...

  2. 46 CFR 185.502 - Crew and passenger list.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Crew and passenger list. 185.502 Section 185.502 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Preparations for Emergencies § 185.502 Crew and passenger list. (a) The...

  3. 47 CFR 87.185 - Scope of service.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Scope of service. 87.185 Section 87.185 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES AVIATION SERVICES Aircraft Stations § 87.185 Scope of service. (a) Aircraft stations must limit their communications to the necessities of safe, efficient,...

  4. 5 CFR 185.113 - Location of hearing.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Location of hearing. 185.113 Section 185... CIVIL REMEDIES § 185.113 Location of hearing. (a) The hearing may be held: (1) In any judicial district... present argument with respect to the location of the hearing. (c) The hearing shall be held at the...

  5. 46 CFR 185.608 - Fuel shutoff valves.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Fuel shutoff valves. 185.608 Section 185.608 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Markings Required § 185.608 Fuel shutoff valves. Remote fuel shutoff stations must be marked...

  6. 46 CFR 185.608 - Fuel shutoff valves.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Fuel shutoff valves. 185.608 Section 185.608 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Markings Required § 185.608 Fuel shutoff valves. Remote fuel shutoff stations must be marked...

  7. 46 CFR 185.608 - Fuel shutoff valves.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Fuel shutoff valves. 185.608 Section 185.608 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Markings Required § 185.608 Fuel shutoff valves. Remote fuel shutoff stations must be marked...

  8. 46 CFR 185.608 - Fuel shutoff valves.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Fuel shutoff valves. 185.608 Section 185.608 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Markings Required § 185.608 Fuel shutoff valves. Remote fuel shutoff stations must be marked...

  9. 5 CFR 185.105 - Review by the reviewing official.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Review by the reviewing official. 185.105... FRAUD CIVIL REMEDIES § 185.105 Review by the reviewing official. If, based on the report of the investigating official under § 185.104(b), the reviewing official determines that there is adequate evidence...

  10. 46 CFR 185.208 - Accidents to machinery.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Accidents to machinery. 185.208 Section 185.208 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Marine Casualties and Voyage Records § 185.208 Accidents to machinery. The owner,...

  11. 5 CFR 185.144 - Right to administrative offset.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Right to administrative offset. 185.144 Section 185.144 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.144 Right to administrative offset. The amount of any penalty or...

  12. 5 CFR 185.144 - Right to administrative offset.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 1 2012-01-01 2012-01-01 false Right to administrative offset. 185.144 Section 185.144 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.144 Right to administrative offset. The amount of any penalty or assessment which has become final, or for which...

  13. 5 CFR 185.144 - Right to administrative offset.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Right to administrative offset. 185.144 Section 185.144 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.144 Right to administrative offset. The amount of any penalty or...

  14. 46 CFR 172.185 - Permeability of spaces.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Permeability of spaces. 172.185 Section 172.185 Shipping... Under Subchapter O of This Chapter § 172.185 Permeability of spaces. (a) When doing the calculations required in § 172.170, the permeability of a floodable space other than a machinery space must be as...

  15. 5 CFR 185.129 - Computation of time.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Computation of time. 185.129 Section 185.129 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.129 Computation of time. (a) In computing any period of time under this part or...

  16. 5 CFR 185.129 - Computation of time.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Computation of time. 185.129 Section 185.129 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.129 Computation of time. (a) In computing any period of time under this part or...

  17. 46 CFR 185.524 - Fire fighting drills and training.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Fire fighting drills and training. 185.524 Section 185.524 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Preparations for Emergencies § 185.524 Fire fighting drills and training. (a) The master shall conduct sufficient...

  18. 5 CFR 185.115 - Separation of functions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Separation of functions. 185.115 Section 185.115 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.115 Separation of functions. (a) The investigating official, the...

  19. 5 CFR 185.115 - Separation of functions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Separation of functions. 185.115 Section 185.115 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.115 Separation of functions. (a) The investigating official, the...

  20. 5 CFR 185.115 - Separation of functions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Separation of functions. 185.115 Section 185.115 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.115 Separation of functions. (a) The investigating official, the...

  1. 5 CFR 185.115 - Separation of functions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Separation of functions. 185.115 Section 185.115 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.115 Separation of functions. (a) The investigating official, the...

  2. 5 CFR 185.115 - Separation of functions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 1 2012-01-01 2012-01-01 false Separation of functions. 185.115 Section 185.115 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.115 Separation of functions. (a) The investigating official, the...

  3. 46 CFR 185.508 - Wearing of life jackets.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Wearing of life jackets. 185.508 Section 185.508... TONS) OPERATIONS Preparations for Emergencies § 185.508 Wearing of life jackets. (a) The master of a vessel shall require passengers to don life jackets when possible hazardous conditions exist,...

  4. 46 CFR 185.516 - Life jacket placards.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Life jacket placards. 185.516 Section 185.516 Shipping...) OPERATIONS Preparations for Emergencies § 185.516 Life jacket placards. (a) Placards containing instructions for the donning and use of the life jackets aboard the vessel must be posted in conspicuous...

  5. 7 CFR 18.5 - Formal complaint procedure.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 1 2012-01-01 2012-01-01 false Formal complaint procedure. 18.5 Section 18.5... EXTENSION SERVICES § 18.5 Formal complaint procedure. A procedure shall be provided for the filing of a... origin, sex, or religion. (b) Time limits for processing. The procedure will include time limits for...

  6. 7 CFR 18.5 - Formal complaint procedure.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 1 2011-01-01 2011-01-01 false Formal complaint procedure. 18.5 Section 18.5... EXTENSION SERVICES § 18.5 Formal complaint procedure. A procedure shall be provided for the filing of a... origin, sex, or religion. (b) Time limits for processing. The procedure will include time limits for...

  7. 7 CFR 18.5 - Formal complaint procedure.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 1 2014-01-01 2014-01-01 false Formal complaint procedure. 18.5 Section 18.5... EXTENSION SERVICES § 18.5 Formal complaint procedure. A procedure shall be provided for the filing of a... origin, sex, or religion. (b) Time limits for processing. The procedure will include time limits for...

  8. 7 CFR 18.5 - Formal complaint procedure.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Formal complaint procedure. 18.5 Section 18.5... EXTENSION SERVICES § 18.5 Formal complaint procedure. A procedure shall be provided for the filing of a... origin, sex, or religion. (b) Time limits for processing. The procedure will include time limits for...

  9. 7 CFR 18.5 - Formal complaint procedure.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 1 2013-01-01 2013-01-01 false Formal complaint procedure. 18.5 Section 18.5... EXTENSION SERVICES § 18.5 Formal complaint procedure. A procedure shall be provided for the filing of a... origin, sex, or religion. (b) Time limits for processing. The procedure will include time limits for...

  10. 46 CFR 185.704 - Maintenance of falls.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Maintenance of falls. 185.704 Section 185.704 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Operational Readiness, Maintenance, and Inspection of Lifesaving Equipment § 185.704...

  11. 46 CFR 185.206 - Written report of marine casualty.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Written report of marine casualty. 185.206 Section 185... 100 GROSS TONS) OPERATIONS Marine Casualties and Voyage Records § 185.206 Written report of marine... of any marine casualty. This written report is in addition to the immediate notice required by...

  12. 46 CFR 185.720 - Weekly maintenance and inspections.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Weekly maintenance and inspections. 185.720 Section 185.720 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Operational Readiness, Maintenance, and Inspection of Lifesaving Equipment § 185.720 Weekly maintenance and...

  13. 21 CFR 160.185 - Dried egg yolks.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 2 2012-04-01 2012-04-01 false Dried egg yolks. 160.185 Section 160.185 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION EGGS AND EGG PRODUCTS Requirements for Specific Standardized Eggs and Egg Products § 160.185 Dried egg yolks. (a) Dried egg...

  14. 40 CFR 792.185 - Reporting of study results.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 31 2010-07-01 2010-07-01 true Reporting of study results. 792.185 Section 792.185 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT (CONTINUED) GOOD LABORATORY PRACTICE STANDARDS Records and Reports § 792.185 Reporting of study results. (a) A final report shall...

  15. 40 CFR 160.185 - Reporting of study results.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Reporting of study results. 160.185 Section 160.185 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS GOOD LABORATORY PRACTICE STANDARDS Records and Reports § 160.185 Reporting of study results. (a) A final report shall be prepared for each...

  16. 46 CFR 185.608 - Fuel shutoff valves.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Fuel shutoff valves. 185.608 Section 185.608 Shipping...) OPERATIONS Markings Required § 185.608 Fuel shutoff valves. Remote fuel shutoff stations must be marked in clearly legible letters at least 25 millimeters (1 inch) high indicating purpose of the valve...

  17. 5 CFR 185.139 - Appeal to authority head.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Appeal to authority head. 185.139 Section 185.139 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.139 Appeal to authority head. (a) Any defendant who has filed a timely answer and who is determined in an initial...

  18. 5 CFR 185.144 - Right to administrative offset.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Right to administrative offset. 185.144 Section 185.144 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.144 Right to administrative offset. The amount of any penalty or assessment which has become final, or for which...

  19. 46 CFR 185.360 - Use of auto pilot.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Use of auto pilot. 185.360 Section 185.360 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Miscellaneous Operating Requirements § 185.360 Use of auto pilot. Whenever an automatic pilot...

  20. 46 CFR 185.360 - Use of auto pilot.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Use of auto pilot. 185.360 Section 185.360 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Miscellaneous Operating Requirements § 185.360 Use of auto pilot. Whenever an automatic pilot...

  1. 46 CFR 185.360 - Use of auto pilot.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Use of auto pilot. 185.360 Section 185.360 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Miscellaneous Operating Requirements § 185.360 Use of auto pilot. Whenever an automatic pilot...

  2. 46 CFR 185.612 - Fire protection equipment.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Fire protection equipment. 185.612 Section 185.612... TONS) OPERATIONS Markings Required § 185.612 Fire protection equipment. (a) Complete but simple instructions for the operation of a fixed gas fire extinguishing system must be located in a conspicuous...

  3. 40 CFR 792.185 - Reporting of study results.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 32 2011-07-01 2011-07-01 false Reporting of study results. 792.185 Section 792.185 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT (CONTINUED) GOOD LABORATORY PRACTICE STANDARDS Records and Reports § 792.185 Reporting of study results. (a) A final report shall...

  4. 5 CFR 185.129 - Computation of time.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Computation of time. 185.129 Section 185.129 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.129 Computation of time. (a) In computing any period of time under this part or in an order issued thereunder, the time...

  5. 5 CFR 185.129 - Computation of time.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 1 2012-01-01 2012-01-01 false Computation of time. 185.129 Section 185.129 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.129 Computation of time. (a) In computing any period of time under this part or...

  6. 46 CFR 185.206 - Written report of marine casualty.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Written report of marine casualty. 185.206 Section 185... 100 GROSS TONS) OPERATIONS Marine Casualties and Voyage Records § 185.206 Written report of marine... of any marine casualty. This written report is in addition to the immediate notice required by...

  7. 46 CFR 185.206 - Written report of marine casualty.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Written report of marine casualty. 185.206 Section 185... 100 GROSS TONS) OPERATIONS Marine Casualties and Voyage Records § 185.206 Written report of marine... of any marine casualty. This written report is in addition to the immediate notice required by...

  8. 46 CFR 185.206 - Written report of marine casualty.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Written report of marine casualty. 185.206 Section 185... 100 GROSS TONS) OPERATIONS Marine Casualties and Voyage Records § 185.206 Written report of marine... of any marine casualty. This written report is in addition to the immediate notice required by...

  9. 46 CFR 185.206 - Written report of marine casualty.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Written report of marine casualty. 185.206 Section 185... 100 GROSS TONS) OPERATIONS Marine Casualties and Voyage Records § 185.206 Written report of marine... of any marine casualty. This written report is in addition to the immediate notice required by...

  10. 46 CFR 185.360 - Use of auto pilot.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Use of auto pilot. 185.360 Section 185.360 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Miscellaneous Operating Requirements § 185.360 Use of auto pilot. Whenever an automatic pilot...

  11. 46 CFR 185.524 - Fire fighting drills and training.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Fire fighting drills and training. 185.524 Section 185... 100 GROSS TONS) OPERATIONS Preparations for Emergencies § 185.524 Fire fighting drills and training. (a) The master shall conduct sufficient fire drills to make sure that each crew member is...

  12. 46 CFR 185.524 - Fire fighting drills and training.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Fire fighting drills and training. 185.524 Section 185... 100 GROSS TONS) OPERATIONS Preparations for Emergencies § 185.524 Fire fighting drills and training. (a) The master shall conduct sufficient fire drills to make sure that each crew member is...

  13. 46 CFR 185.524 - Fire fighting drills and training.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Fire fighting drills and training. 185.524 Section 185... 100 GROSS TONS) OPERATIONS Preparations for Emergencies § 185.524 Fire fighting drills and training. (a) The master shall conduct sufficient fire drills to make sure that each crew member is...

  14. 46 CFR 185.524 - Fire fighting drills and training.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Fire fighting drills and training. 185.524 Section 185... 100 GROSS TONS) OPERATIONS Preparations for Emergencies § 185.524 Fire fighting drills and training. (a) The master shall conduct sufficient fire drills to make sure that each crew member is...

  15. 21 CFR 73.185 - Haematococcus algae meal.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Haematococcus algae meal. 73.185 Section 73.185... COLOR ADDITIVES EXEMPT FROM CERTIFICATION Foods § 73.185 Haematococcus algae meal. (a) Identity. (1) The color additive haematococcus algae meal consists of the comminuted and dried cells of the...

  16. 21 CFR 73.185 - Haematococcus algae meal.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Haematococcus algae meal. 73.185 Section 73.185... COLOR ADDITIVES EXEMPT FROM CERTIFICATION Foods § 73.185 Haematococcus algae meal. (a) Identity. (1) The color additive haematococcus algae meal consists of the comminuted and dried cells of the...

  17. 46 CFR 172.185 - Permeability of spaces.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Permeability of spaces. 172.185 Section 172.185 Shipping... Under Subchapter O of This Chapter § 172.185 Permeability of spaces. (a) When doing the calculations required in § 172.170, the permeability of a floodable space other than a machinery space must be as...

  18. 46 CFR 172.185 - Permeability of spaces.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Permeability of spaces. 172.185 Section 172.185 Shipping... Under Subchapter O of This Chapter § 172.185 Permeability of spaces. (a) When doing the calculations required in § 172.170, the permeability of a floodable space other than a machinery space must be as...

  19. 46 CFR 172.185 - Permeability of spaces.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Permeability of spaces. 172.185 Section 172.185 Shipping... Under Subchapter O of This Chapter § 172.185 Permeability of spaces. (a) When doing the calculations required in § 172.170, the permeability of a floodable space other than a machinery space must be as...

  20. 46 CFR 185.360 - Use of auto pilot.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Use of auto pilot. 185.360 Section 185.360 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Miscellaneous Operating Requirements § 185.360 Use of auto pilot. Whenever an automatic pilot...

  1. 5 CFR 185.136 - Post-hearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Post-hearing briefs. 185.136 Section 185... CIVIL REMEDIES § 185.136 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing...

  2. 5 CFR 185.136 - Post-hearing briefs.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Post-hearing briefs. 185.136 Section 185... CIVIL REMEDIES § 185.136 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing...

  3. 5 CFR 185.136 - Post-hearing briefs.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Post-hearing briefs. 185.136 Section 185... CIVIL REMEDIES § 185.136 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing...

  4. 5 CFR 185.136 - Post-hearing briefs.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 1 2012-01-01 2012-01-01 false Post-hearing briefs. 185.136 Section 185... CIVIL REMEDIES § 185.136 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing...

  5. 46 CFR 185.508 - Wearing of life jackets.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Wearing of life jackets. 185.508 Section 185.508... TONS) OPERATIONS Preparations for Emergencies § 185.508 Wearing of life jackets. (a) The master of a vessel shall require passengers to don life jackets when possible hazardous conditions exist,...

  6. 46 CFR 185.508 - Wearing of life jackets.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Wearing of life jackets. 185.508 Section 185.508... TONS) OPERATIONS Preparations for Emergencies § 185.508 Wearing of life jackets. (a) The master of a vessel shall require passengers to don life jackets when possible hazardous conditions exist,...

  7. 46 CFR 185.516 - Life jacket placards.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Life jacket placards. 185.516 Section 185.516 Shipping...) OPERATIONS Preparations for Emergencies § 185.516 Life jacket placards. (a) Placards containing instructions for the donning and use of the life jackets aboard the vessel must be posted in conspicuous...

  8. 46 CFR 185.508 - Wearing of life jackets.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Wearing of life jackets. 185.508 Section 185.508... TONS) OPERATIONS Preparations for Emergencies § 185.508 Wearing of life jackets. (a) The master of a vessel shall require passengers to don life jackets when possible hazardous conditions exist,...

  9. 46 CFR 185.516 - Life jacket placards.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Life jacket placards. 185.516 Section 185.516 Shipping...) OPERATIONS Preparations for Emergencies § 185.516 Life jacket placards. (a) Placards containing instructions for the donning and use of the life jackets aboard the vessel must be posted in conspicuous...

  10. 46 CFR 185.516 - Life jacket placards.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Life jacket placards. 185.516 Section 185.516 Shipping...) OPERATIONS Preparations for Emergencies § 185.516 Life jacket placards. (a) Placards containing instructions for the donning and use of the life jackets aboard the vessel must be posted in conspicuous...

  11. 46 CFR 185.516 - Life jacket placards.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Life jacket placards. 185.516 Section 185.516 Shipping...) OPERATIONS Preparations for Emergencies § 185.516 Life jacket placards. (a) Placards containing instructions for the donning and use of the life jackets aboard the vessel must be posted in conspicuous...

  12. 46 CFR 185.508 - Wearing of life jackets.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Wearing of life jackets. 185.508 Section 185.508... TONS) OPERATIONS Preparations for Emergencies § 185.508 Wearing of life jackets. (a) The master of a vessel shall require passengers to don life jackets when possible hazardous conditions exist,...

  13. 46 CFR 185.612 - Fire protection equipment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Fire protection equipment. 185.612 Section 185.612... TONS) OPERATIONS Markings Required § 185.612 Fire protection equipment. (a) Complete but simple instructions for the operation of a fixed gas fire extinguishing system must be located in a conspicuous...

  14. 46 CFR 185.612 - Fire protection equipment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Fire protection equipment. 185.612 Section 185.612... TONS) OPERATIONS Markings Required § 185.612 Fire protection equipment. (a) Complete but simple instructions for the operation of a fixed gas fire extinguishing system must be located in a conspicuous...

  15. 46 CFR 185.340 - Vessels carrying vehicles.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Vessels carrying vehicles. 185.340 Section 185.340 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Miscellaneous Operating Requirements § 185.340 Vessels carrying vehicles....

  16. 46 CFR 185.208 - Accidents to machinery.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Accidents to machinery. 185.208 Section 185.208 Shipping...) OPERATIONS Marine Casualties and Voyage Records § 185.208 Accidents to machinery. The owner, managing operator, or master shall report damage to a boiler, unfired pressure vessel, or machinery that...

  17. 5 CFR 185.114 - Parties to the hearing.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Parties to the hearing. 185.114 Section 185.114 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.114 Parties to the hearing. (a) The parties to the hearing shall be...

  18. 5 CFR 185.138 - Reconsideration of initial decision.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Reconsideration of initial decision. 185.138 Section 185.138 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.138 Reconsideration of initial decision. (a) Except as provided...

  19. 5 CFR 185.108 - Service of complaint.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Service of complaint. 185.108 Section 185.108 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.108 Service of complaint. (a) Service of a complaint must be made by certified...

  20. 5 CFR 185.112 - Notice of hearing.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Notice of hearing. 185.112 Section 185.112 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.112 Notice of hearing. (a) When the ALJ receives the complaint and answer, the...

  1. 5 CFR 185.118 - Rights of parties.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Rights of parties. 185.118 Section 185.118 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.118 Rights of parties. Except as otherwise limited by this part, all parties...

  2. 5 CFR 185.106 - Prerequisites for issuing a complaint.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Prerequisites for issuing a complaint. 185.106 Section 185.106 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.106 Prerequisites for issuing a complaint. (a) The...

  3. 5 CFR 185.121 - Disclosure of documents.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Disclosure of documents. 185.121 Section 185.121 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.121 Disclosure of documents. (a) Upon written request to the...

  4. 5 CFR 185.144 - Right to administrative offset.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Right to administrative offset. 185.144 Section 185.144 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.144 Right to administrative offset. The amount of any penalty or...

  5. 5 CFR 185.146 - Compromise or settlement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Compromise or settlement. 185.146 Section 185.146 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.146 Compromise or settlement. (a) Parties may make offers of compromise...

  6. 5 CFR 185.113 - Location of hearing.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Location of hearing. 185.113 Section 185.113 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.113 Location of hearing. (a) The hearing may be held: (1) In any judicial...

  7. 5 CFR 185.119 - Authority of the ALJ.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Authority of the ALJ. 185.119 Section 185.119 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.119 Authority of the ALJ. (a) The ALJ shall conduct a fair and impartial...

  8. 46 CFR 185.115 - Applicability; preemptive effect.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Applicability; preemptive effect. 185.115 Section 185... 100 GROSS TONS) OPERATIONS General Provisions § 185.115 Applicability; preemptive effect. (a) An... occurs after March 11, 1996. (d) The regulations in this part have preemptive effect over State or...

  9. 49 CFR 18.5 - Effect on other issuances.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 1 2013-10-01 2013-10-01 false Effect on other issuances. 18.5 Section 18.5 Transportation Office of the Secretary of Transportation UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND COOPERATIVE AGREEMENTS TO STATE AND LOCAL GOVERNMENTS General § 18.5 Effect on other issuances. All...

  10. 46 CFR 185.910 - Suspension and revocation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Suspension and revocation. 185.910 Section 185.910 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Penalties § 185.910 Suspension and revocation. An individual holding a...

  11. 46 CFR 172.185 - Permeability of spaces.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Permeability of spaces. 172.185 Section 172.185 Shipping... Under Subchapter O of This Chapter § 172.185 Permeability of spaces. (a) When doing the calculations required in § 172.170, the permeability of a floodable space other than a machinery space must be as...

  12. 7 CFR 4279.182-4279.185 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 15 2011-01-01 2011-01-01 false 4279.182-4279.185 Section 4279.182-4279.185 Agriculture Regulations of the Department of Agriculture (Continued) RURAL BUSINESS-COOPERATIVE SERVICE AND RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE GUARANTEED LOANMAKING Business and Industry...

  13. 7 CFR 4279.182-4279.185 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 15 2013-01-01 2013-01-01 false 4279.182-4279.185 Section 4279.182-4279.185 Agriculture Regulations of the Department of Agriculture (Continued) RURAL BUSINESS-COOPERATIVE SERVICE AND RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE GUARANTEED LOANMAKING Business and Industry...

  14. 7 CFR 4279.182-4279.185 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 15 2014-01-01 2014-01-01 false 4279.182-4279.185 Section 4279.182-4279.185 Agriculture Regulations of the Department of Agriculture (Continued) RURAL BUSINESS-COOPERATIVE SERVICE AND RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE GUARANTEED LOANMAKING Business and Industry...

  15. 7 CFR 4279.182-4279.185 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 15 2012-01-01 2012-01-01 false 4279.182-4279.185 Section 4279.182-4279.185 Agriculture Regulations of the Department of Agriculture (Continued) RURAL BUSINESS-COOPERATIVE SERVICE AND RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE GUARANTEED LOANMAKING Business and Industry...

  16. 27 CFR 53.185 - Credit on returns.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... evidence prescribed in the applicable regulations in this subpart and 27 CFR 70.123 (Procedure and... 27 Alcohol, Tobacco Products and Firearms 2 2014-04-01 2014-04-01 false Credit on returns. 53.185... Other Administrative Provisions of Special Application to Manufacturers Taxes § 53.185 Credit on...

  17. 27 CFR 53.185 - Credit on returns.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... evidence prescribed in the applicable regulations in this subpart and 27 CFR 70.123 (Procedure and... 27 Alcohol, Tobacco Products and Firearms 2 2013-04-01 2013-04-01 false Credit on returns. 53.185... Other Administrative Provisions of Special Application to Manufacturers Taxes § 53.185 Credit on...

  18. 5 CFR 185.124 - Subpoenas for attendance at hearing.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Subpoenas for attendance at hearing. 185... PROGRAM FRAUD CIVIL REMEDIES § 185.124 Subpoenas for attendance at hearing. (a) A party wishing to procure... subpoena. (b) A subpoena requiring the attendance and testimony of an individual may also require...

  19. 5 CFR 550.185 - Payment of availability pay.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Payment of availability pay. 550.185 Section 550.185 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PAY... service. (d) Agencies may, at their discretion, provide for the continuation of availability pay when...

  20. 21 CFR 137.185 - Enriched self-rising flour.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 2 2011-04-01 2011-04-01 false Enriched self-rising flour. 137.185 Section 137... Cereal Flours and Related Products § 137.185 Enriched self-rising flour. Enriched self-rising flour... of ingredients, prescribed for self-rising flour by § 137.180, except that: (a) It contains in...

  1. 21 CFR 137.185 - Enriched self-rising flour.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 2 2014-04-01 2014-04-01 false Enriched self-rising flour. 137.185 Section 137... Cereal Flours and Related Products § 137.185 Enriched self-rising flour. Enriched self-rising flour... of ingredients, prescribed for self-rising flour by § 137.180, except that: (a) It contains in...

  2. 21 CFR 137.185 - Enriched self-rising flour.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Enriched self-rising flour. 137.185 Section 137... Cereal Flours and Related Products § 137.185 Enriched self-rising flour. Enriched self-rising flour... of ingredients, prescribed for self-rising flour by § 137.180, except that: (a) It contains in...

  3. 21 CFR 137.185 - Enriched self-rising flour.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 2 2012-04-01 2012-04-01 false Enriched self-rising flour. 137.185 Section 137... Cereal Flours and Related Products § 137.185 Enriched self-rising flour. Enriched self-rising flour... of ingredients, prescribed for self-rising flour by § 137.180, except that: (a) It contains in...

  4. 46 CFR 185.506 - Passenger safety orientation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Passenger safety orientation. 185.506 Section 185.506 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS... safety orientation. If only a small number of passengers embark at a port after the original muster...

  5. 46 CFR 185.506 - Passenger safety orientation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Passenger safety orientation. 185.506 Section 185.506 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS... safety orientation. If only a small number of passengers embark at a port after the original muster...

  6. 46 CFR 185.506 - Passenger safety orientation.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Passenger safety orientation. 185.506 Section 185.506 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS... safety orientation. If only a small number of passengers embark at a port after the original muster...

  7. 46 CFR 185.506 - Passenger safety orientation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Passenger safety orientation. 185.506 Section 185.506 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS... safety orientation. If only a small number of passengers embark at a port after the original muster...

  8. 46 CFR 185.506 - Passenger safety orientation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Passenger safety orientation. 185.506 Section 185.506 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS... safety orientation. If only a small number of passengers embark at a port after the original muster...

  9. 5 CFR 185.136 - Post-hearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... CIVIL REMEDIES § 185.136 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing such... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Post-hearing briefs. 185.136 Section...

  10. 37 CFR 1.85 - Corrections to drawings.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Corrections to drawings. 1.85... COMMERCE GENERAL RULES OF PRACTICE IN PATENT CASES National Processing Provisions The Drawings § 1.85 Corrections to drawings. (a) A utility or plant application will not be placed on the files for...

  11. 46 CFR 185.352 - Ventilation of gasoline machinery spaces.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Ventilation of gasoline machinery spaces. 185.352... (UNDER 100 GROSS TONS) OPERATIONS Miscellaneous Operating Requirements § 185.352 Ventilation of gasoline machinery spaces. The mechanical exhaust for the ventilation of a gasoline machinery space, required...

  12. 46 CFR 185.352 - Ventilation of gasoline machinery spaces.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Ventilation of gasoline machinery spaces. 185.352... (UNDER 100 GROSS TONS) OPERATIONS Miscellaneous Operating Requirements § 185.352 Ventilation of gasoline machinery spaces. The mechanical exhaust for the ventilation of a gasoline machinery space, required...

  13. 12 CFR 18.5 - Alternative annual disclosure statements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Board (12 CFR part 225). Such schedules must be comparable to the Call Report schedules enumerated in... 12 Banks and Banking 1 2013-01-01 2013-01-01 false Alternative annual disclosure statements. 18.5... FINANCIAL AND OTHER INFORMATION BY NATIONAL BANKS § 18.5 Alternative annual disclosure statements. The §...

  14. 12 CFR 18.5 - Alternative annual disclosure statements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Board (12 CFR part 225). Such schedules must be comparable to the Call Report schedules enumerated in... 12 Banks and Banking 1 2011-01-01 2011-01-01 false Alternative annual disclosure statements. 18.5... FINANCIAL AND OTHER INFORMATION BY NATIONAL BANKS § 18.5 Alternative annual disclosure statements. The §...

  15. 36 CFR 223.185 - Scope and applicability.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ....185 Section 223.185 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE SALE AND DISPOSAL OF NATIONAL FOREST SYSTEM TIMBER The Forest Resources Conservation and Shortage Relief... Forest Resources Conservation and Shortage Relief Act of 1990 (16 U.S.C. 620, et seq.) that...

  16. 37 CFR 1.85 - Corrections to drawings.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2013-07-01 2013-07-01 false Corrections to drawings. 1.85... COMMERCE GENERAL RULES OF PRACTICE IN PATENT CASES National Processing Provisions The Drawings § 1.85 Corrections to drawings. (a) A utility or plant application will not be placed on the files for...

  17. 37 CFR 1.85 - Corrections to drawings.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2012-07-01 2012-07-01 false Corrections to drawings. 1.85... COMMERCE GENERAL RULES OF PRACTICE IN PATENT CASES National Processing Provisions The Drawings § 1.85 Corrections to drawings. (a) A utility or plant application will not be placed on the files for...

  18. 37 CFR 1.85 - Corrections to drawings.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2011-07-01 2011-07-01 false Corrections to drawings. 1.85... COMMERCE GENERAL RULES OF PRACTICE IN PATENT CASES National Processing Provisions The Drawings § 1.85 Corrections to drawings. (a) A utility or plant application will not be placed on the files for...

  19. 27 CFR 44.185 - Label or notice.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2014-04-01 2014-04-01 false Label or notice. 44.185... Papers and Tubes by Manufacturers and Export Warehouse Proprietors Packaging Requirements § 44.185 Label... subpart, have adequately imprinted thereon, or on a label securely affixed thereto, the words...

  20. 27 CFR 44.185 - Label or notice.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2013-04-01 2013-04-01 false Label or notice. 44.185... Papers and Tubes by Manufacturers and Export Warehouse Proprietors Packaging Requirements § 44.185 Label... subpart, have adequately imprinted thereon, or on a label securely affixed thereto, the words...

  1. 27 CFR 44.185 - Label or notice.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Label or notice. 44.185... Papers and Tubes by Manufacturers and Export Warehouse Proprietors Packaging Requirements § 44.185 Label... subpart, have adequately imprinted thereon, or on a label securely affixed thereto, the words...

  2. 27 CFR 44.185 - Label or notice.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2011-04-01 2011-04-01 false Label or notice. 44.185... Papers and Tubes by Manufacturers and Export Warehouse Proprietors Packaging Requirements § 44.185 Label... subpart, have adequately imprinted thereon, or on a label securely affixed thereto, the words...

  3. 27 CFR 44.185 - Label or notice.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2012-04-01 2011-04-01 true Label or notice. 44.185 Section 44.185 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY (CONTINUED) TOBACCO EXPORTATION OF TOBACCO PRODUCTS AND CIGARETTE PAPERS AND TUBES, WITHOUT PAYMENT OF TAX, OR WITH DRAWBACK...

  4. 27 CFR 40.185 - Retention of records.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2011-04-01 2011-04-01 false Retention of records. 40.185 Section 40.185 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY (CONTINUED) TOBACCO MANUFACTURE OF TOBACCO PRODUCTS, CIGARETTE PAPERS AND TUBES, AND PROCESSED TOBACCO Operations...

  5. 5 CFR 185.139 - Appeal to authority head.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 1 2012-01-01 2012-01-01 false Appeal to authority head. 185.139 Section... FRAUD CIVIL REMEDIES § 185.139 Appeal to authority head. (a) Any defendant who has filed a timely answer... such decision to the authority head by filing a notice of appeal with the authority head in...

  6. 5 CFR 185.139 - Appeal to authority head.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Appeal to authority head. 185.139 Section... FRAUD CIVIL REMEDIES § 185.139 Appeal to authority head. (a) Any defendant who has filed a timely answer... such decision to the authority head by filing a notice of appeal with the authority head in...

  7. 5 CFR 185.139 - Appeal to authority head.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Appeal to authority head. 185.139 Section... FRAUD CIVIL REMEDIES § 185.139 Appeal to authority head. (a) Any defendant who has filed a timely answer... such decision to the authority head by filing a notice of appeal with the authority head in...

  8. 5 CFR 185.139 - Appeal to authority head.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Appeal to authority head. 185.139 Section... FRAUD CIVIL REMEDIES § 185.139 Appeal to authority head. (a) Any defendant who has filed a timely answer... such decision to the authority head by filing a notice of appeal with the authority head in...

  9. 27 CFR 53.185 - Credit on returns.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... evidence prescribed in the applicable regulations in this subpart and 27 CFR 70.123 (Procedure and... 27 Alcohol, Tobacco Products and Firearms 2 2012-04-01 2011-04-01 true Credit on returns. 53.185... Other Administrative Provisions of Special Application to Manufacturers Taxes § 53.185 Credit on...

  10. 49 CFR 173.185 - Lithium cells and batteries.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 2 2012-10-01 2012-10-01 false Lithium cells and batteries. 173.185 Section 173... Class 7 § 173.185 Lithium cells and batteries. (a) Cells and batteries. A lithium cell or battery, including a lithium polymer cell or battery and a lithium-ion cell or battery, must conform to all of...

  11. 49 CFR 173.185 - Lithium cells and batteries.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 2 2013-10-01 2013-10-01 false Lithium cells and batteries. 173.185 Section 173... Class 7 § 173.185 Lithium cells and batteries. (a) Cells and batteries. A lithium cell or battery, including a lithium polymer cell or battery and a lithium-ion cell or battery, must conform to all of...

  12. 49 CFR 173.185 - Lithium cells and batteries.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 2 2011-10-01 2011-10-01 false Lithium cells and batteries. 173.185 Section 173... Class 7 § 173.185 Lithium cells and batteries. (a) Cells and batteries. A lithium cell or battery, including a lithium polymer cell or battery and a lithium-ion cell or battery, must conform to all of...

  13. 5 CFR 185.116 - Ex parte contacts.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Ex parte contacts. 185.116 Section 185.116 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD... about the status of a case or asking routine questions concerning administrative functions or procedures....

  14. 5 CFR 185.141 - Stay pending appeal.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Stay pending appeal. 185.141 Section 185.141 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD... disposition of a motion for reconsideration or of an appeal to the authority head. (b) No administrative...

  15. 46 CFR 185.610 - Watertight doors and watertight hatches.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Watertight doors and watertight hatches. 185.610 Section... (UNDER 100 GROSS TONS) OPERATIONS Markings Required § 185.610 Watertight doors and watertight hatches. Watertight doors and watertight hatches must be marked on both sides in clearly legible letters at least...

  16. 46 CFR 185.610 - Watertight doors and watertight hatches.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Watertight doors and watertight hatches. 185.610 Section... (UNDER 100 GROSS TONS) OPERATIONS Markings Required § 185.610 Watertight doors and watertight hatches. Watertight doors and watertight hatches must be marked on both sides in clearly legible letters at least...

  17. 46 CFR 185.610 - Watertight doors and watertight hatches.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Watertight doors and watertight hatches. 185.610 Section... (UNDER 100 GROSS TONS) OPERATIONS Markings Required § 185.610 Watertight doors and watertight hatches. Watertight doors and watertight hatches must be marked on both sides in clearly legible letters at least...

  18. 46 CFR 185.610 - Watertight doors and watertight hatches.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Watertight doors and watertight hatches. 185.610 Section... (UNDER 100 GROSS TONS) OPERATIONS Markings Required § 185.610 Watertight doors and watertight hatches. Watertight doors and watertight hatches must be marked on both sides in clearly legible letters at least...

  19. 46 CFR 185.610 - Watertight doors and watertight hatches.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Watertight doors and watertight hatches. 185.610 Section... (UNDER 100 GROSS TONS) OPERATIONS Markings Required § 185.610 Watertight doors and watertight hatches. Watertight doors and watertight hatches must be marked on both sides in clearly legible letters at least...

  20. TMEM106B p.T185S regulates TMEM106B protein levels: implications for frontotemporal dementia.

    PubMed

    Nicholson, Alexandra M; Finch, Nicole A; Wojtas, Aleksandra; Baker, Matt C; Perkerson, Ralph B; Castanedes-Casey, Monica; Rousseau, Linda; Benussi, Luisa; Binetti, Giuliano; Ghidoni, Roberta; Hsiung, Ging-Yuek R; Mackenzie, Ian R; Finger, Elizabeth; Boeve, Bradley F; Ertekin-Taner, Nilüfer; Graff-Radford, Neill R; Dickson, Dennis W; Rademakers, Rosa

    2013-09-01

    Frontotemporal lobar degeneration (FTLD) is the second leading cause of dementia in individuals under age 65. In many patients, the predominant pathology includes neuronal cytoplasmic or intranuclear inclusions of ubiquitinated TAR DNA binding protein 43 (FTLD-TDP). Recently, a genome-wide association study identified the first FTLD-TDP genetic risk factor, in which variants in and around the TMEM106B gene (top SNP rs1990622) were significantly associated with FTLD-TDP risk. Intriguingly, the most significant association was in FTLD-TDP patients carrying progranulin (GRN) mutations. Here, we investigated to what extent the coding variant, rs3173615 (p.T185S) in linkage disequilibrium with rs1990622, affects progranulin protein (PGRN) biology and transmembrane protein 106 B (TMEM106B) regulation. First, we confirmed the association of TMEM106B variants with FTLD-TDP in a new cohort of GRN mutation carriers. We next generated and characterized a TMEM106B-specific antibody for investigation of this protein. Enzyme-linked immunoassay analysis of progranulin protein levels showed similar effects upon T185 and S185 TMEM106B over-expression. However, over-expression of T185 consistently led to higher TMEM106B protein levels than S185. Cycloheximide treatment experiments revealed that S185 degrades faster than T185 TMEM106B, potentially due to differences in N-glycosylation at residue N183. Together, our results provide a potential mechanism by which TMEM106B variants lead to differences in FTLD-TDP risk. We studied the p.T185S TMEM106B genetic variant previously implicated in frontotemporal dementia with TAR DNA binding protein 43 pathology caused by progranulin mutations. Our cell culture studies provide evidence that the protective S185 isoform is degraded more rapidly than T185 TMEM106B, potentially due to differences in glycosylation. These findings suggest that low TMEM106B levels might protect against FTLD-TDP in these patients. PMID:23742080

  1. 185. SOUTH ELEVATIONS OF (LEFT TO RIGHT) BOILER BUILDING (1919); ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    185. SOUTH ELEVATIONS OF (LEFT TO RIGHT) BOILER BUILDING (1919); CUPOLA BUILDING (1898); PUMP HOUSE ADDITION, BEHIND TRESTLE (1906); BRIQUETTING PLANT (1906). - Quincy Mining Company, Hancock, Houghton County, MI

  2. 46 CFR 185.260 - Reports of potential vessel casualty.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... (UNDER 100 GROSS TONS) OPERATIONS Marine Casualties and Voyage Records § 185.260 Reports of potential... imperiled: (1) The Coast Guard district rescue coordination center (RCC) cognizant over the area in...

  3. 46 CFR 185.202 - Notice of casualty.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Regulations (CFR) part 1904. (c) Notice given as required by § 185.203 satisfies the requirement of this... fitness for service or route, including but not limited to fire, flooding, failure of or damage to...

  4. 46 CFR 185.202 - Notice of casualty.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Regulations (CFR) part 1904. (c) Notice given as required by § 185.203 satisfies the requirement of this... fitness for service or route, including but not limited to fire, flooding, failure of or damage to...

  5. 46 CFR 185.202 - Notice of casualty.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Regulations (CFR) part 1904. (c) Notice given as required by § 185.203 satisfies the requirement of this... fitness for service or route, including but not limited to fire, flooding, failure of or damage to...

  6. ERECTION PLAN FOR BEAM SPANS FROM BENT NO. 185 TO ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    ERECTION PLAN FOR BEAM SPANS FROM BENT NO. 185 TO EAST ABUTMENT AT EAST APPROACH, APALACHICOLA RIVER BRIDGE, SHEET 5509-E7 - Apalachicola River Bridge, State Route 20 spanning the Apalachicola River, Blountstown, Calhoun County, FL

  7. 40 CFR 18.5 - Qualifications for Environmental Protection Research Fellowships.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Protection Research Fellowships. 18.5 Section 18.5 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL ENVIRONMENTAL PROTECTION RESEARCH FELLOWSHIPS AND SPECIAL RESEARCH CONSULTANTS FOR ENVIRONMENTAL PROTECTION § 18.5 Qualifications for Environmental Protection Research Fellowships. Scholastic and...

  8. 40 CFR 18.5 - Qualifications for Environmental Protection Research Fellowships.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Protection Research Fellowships. 18.5 Section 18.5 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL ENVIRONMENTAL PROTECTION RESEARCH FELLOWSHIPS AND SPECIAL RESEARCH CONSULTANTS FOR ENVIRONMENTAL PROTECTION § 18.5 Qualifications for Environmental Protection Research Fellowships. Scholastic and...

  9. 40 CFR 18.5 - Qualifications for Environmental Protection Research Fellowships.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Protection Research Fellowships. 18.5 Section 18.5 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL ENVIRONMENTAL PROTECTION RESEARCH FELLOWSHIPS AND SPECIAL RESEARCH CONSULTANTS FOR ENVIRONMENTAL PROTECTION § 18.5 Qualifications for Environmental Protection Research Fellowships. Scholastic and...

  10. 40 CFR 18.5 - Qualifications for Environmental Protection Research Fellowships.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Protection Research Fellowships. 18.5 Section 18.5 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL ENVIRONMENTAL PROTECTION RESEARCH FELLOWSHIPS AND SPECIAL RESEARCH CONSULTANTS FOR ENVIRONMENTAL PROTECTION § 18.5 Qualifications for Environmental Protection Research Fellowships. Scholastic and...

  11. 40 CFR 18.5 - Qualifications for Environmental Protection Research Fellowships.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Protection Research Fellowships. 18.5 Section 18.5 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL ENVIRONMENTAL PROTECTION RESEARCH FELLOWSHIPS AND SPECIAL RESEARCH CONSULTANTS FOR ENVIRONMENTAL PROTECTION § 18.5 Qualifications for Environmental Protection Research Fellowships. Scholastic and...

  12. Atomic Mass and Nuclear Binding Energy for I-185 (Iodine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume A `Nuclei with Z = 1 - 54' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms'. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope I-185 (Iodine, atomic number Z = 53, mass number A = 185).

  13. History of the 185-/189-D thermal hydraulics laboratory and its effects on reactor operations at the Hanford Site

    SciTech Connect

    Gerber, M.S.

    1994-09-01

    The 185-D deaeration building and the 189-D refrigeration building were constructed at Hanford during 1943 and 1944. Both buildings were constructed as part of the influent water cooling system for D reactor. The CMS studies eliminated the need for 185-D function. Early gains in knowledge ended the original function of the 189-D building mission. In 1951, 185-D and 189-D were converted to a thermal-hydraulic laboratory. The experiments held in the thermal-hydraulic lab lead to historic changes in Hanford reactor operations. In late 1951, the exponential physics experiments were moved to the 189-D building. In 1958, new production reactor experiments were begun in 185/189-D. In 1959, Plutonium Recycle Test Reactor experiments were added to the 185/189-D facility. By 1960, the 185/189-D thermal hydraulics laboratory was one of the few full service facilities of its type in the nation. During the years 1961--1963 tests continued in the facility in support of existing reactors, new production reactors, and the Plutonium Recycle Test Reactor. In 1969, Fast Flux Test Facility developmental testings began in the facility. Simulations in 185/189-D building aided in the N Reactor repairs in the 1980`s. In 1994 the facility was nominated to the National Register of Historic Places, because of its pioneering role over many years in thermal hydraulics, flow studies, heat transfer, and other reactor coolant support work. During 1994 and 1995 it was demolished in the largest decontamination and decommissioning project thus far in Hanford Site history.

  14. G-protein coupled receptor 34 activates Erk and phosphatidylinositol 3-kinase/Akt pathways and functions as alternative pathway to mediate p185Bcr-Abl-induced transformation and leukemogenesis.

    PubMed

    Zuo, Bo; Li, Mei; Liu, Yulan; Li, Kun; Ma, Shuyun; Cui, Meihua; Qin, Yazhen; Zhu, Honghu; Pan, Xiuying; Guo, Jingzhu; Dai, Zonghan; Yu, Weidong

    2015-07-01

    Tyrosine 177 and the Src homology 2 (SH2) domain play important roles in linking p185Bcr-Abl to downstream pathways critical for cell growth and survival. However, a mutant p185(Y177FR552L) (p185(YR)), in which tyrosine 177 and arginine 552 in the SH2 domain are mutated, is still capable of transforming hematopoietic cells in vitro. Transplant of these cells into syngeneic mice also leads to leukemogenesis, albeit with a phenotype distinct from that produced by wild-type p185Bcr-Abl (p185(wt))-transformed cells. Here we show that G-protein coupled receptor 34 (Gpr34) expression is markedly up-regulated in p185(YR)-transformed cells compared to those transformed by p185(wt). Knockdown of Gpr34 in p185(YR) cells is sufficient to suppress growth factor-independent proliferation and survival in vitro and attenuate leukemogenesis in vivo. The Erk and phosphatidylinositol 3-kinase/Akt pathways are activated in p185(YR) cells and the activation is dependent on Gpr34 expression. These studies identify Gpr34 as an alternative pathway that may mediate p185Bcr-Abl-induced transformation and leukemogenesis. PMID:25363403

  15. 46 CFR 108.185 - Ventilation for enclosed classified locations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false Ventilation for enclosed classified locations. 108.185... enclosed classified locations. (a) The ventilation system for each enclosed classified location must be designed to maintain a pressure differential between the enclosed classified location and each...

  16. 46 CFR 108.185 - Ventilation for enclosed classified locations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false Ventilation for enclosed classified locations. 108.185... enclosed classified locations. (a) The ventilation system for each enclosed classified location must be designed to maintain a pressure differential between the enclosed classified location and each...

  17. 46 CFR 108.185 - Ventilation for enclosed classified locations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Ventilation for enclosed classified locations. 108.185... enclosed classified locations. (a) The ventilation system for each enclosed classified location must be designed to maintain a pressure differential between the enclosed classified location and each...

  18. 46 CFR 108.185 - Ventilation for enclosed classified locations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 4 2014-10-01 2014-10-01 false Ventilation for enclosed classified locations. 108.185... enclosed classified locations. (a) The ventilation system for each enclosed classified location must be designed to maintain a pressure differential between the enclosed classified location and each...

  19. 46 CFR 108.185 - Ventilation for enclosed classified locations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false Ventilation for enclosed classified locations. 108.185... enclosed classified locations. (a) The ventilation system for each enclosed classified location must be designed to maintain a pressure differential between the enclosed classified location and each...

  20. 12 CFR 18.5 - Alternative annual disclosure statements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Board (12 CFR part 225). Such schedules must be comparable to the Call Report schedules enumerated in... 12 Banks and Banking 1 2012-01-01 2012-01-01 false Alternative annual disclosure statements. 18.5... national bank having a class of securities registered pursuant to section 12 of the Securities Exchange...

  1. 12 CFR 18.5 - Alternative annual disclosure statements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Board (12 CFR part 225). Such schedules must be comparable to the Call Report schedules enumerated in... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Alternative annual disclosure statements. 18.5... national bank having a class of securities registered pursuant to section 12 of the Securities Exchange...

  2. 27 CFR 19.185 - Testing scale tanks for accuracy.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Testing scale tanks for... Requirements Tank Requirements § 19.185 Testing scale tanks for accuracy. (a) A proprietor who uses a scale tank for tax determination must ensure the accuracy of the scale through periodic testing. Testing...

  3. 27 CFR 19.185 - Testing scale tanks for accuracy.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2014-04-01 2014-04-01 false Testing scale tanks for... Requirements Tank Requirements § 19.185 Testing scale tanks for accuracy. (a) A proprietor who uses a scale tank for tax determination must ensure the accuracy of the scale through periodic testing. Testing...

  4. 27 CFR 19.185 - Testing scale tanks for accuracy.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2012-04-01 2012-04-01 false Testing scale tanks for... Requirements Tank Requirements § 19.185 Testing scale tanks for accuracy. (a) A proprietor who uses a scale tank for tax determination must ensure the accuracy of the scale through periodic testing. Testing...

  5. 27 CFR 19.185 - Testing scale tanks for accuracy.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2013-04-01 2013-04-01 false Testing scale tanks for... Requirements Tank Requirements § 19.185 Testing scale tanks for accuracy. (a) A proprietor who uses a scale tank for tax determination must ensure the accuracy of the scale through periodic testing. Testing...

  6. 50 CFR 216.185 - Requirements for monitoring.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Low Frequency Active (SURTASS LFA sonar) Sonar § 216.185 Requirements for monitoring. (a) In order to mitigate the taking of marine mammals by SURTASS LFA sonar to the greatest extent practicable, the Holder... sunset); (2) Use low frequency passive SURTASS sonar to listen for vocalizing marine mammals; and (3)...

  7. 46 CFR 185.352 - Ventilation of gasoline machinery spaces.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Ventilation of gasoline machinery spaces. 185.352... machinery spaces. The mechanical exhaust for the ventilation of a gasoline machinery space, required by... sufficient to insure at least one complete change of air in the space served....

  8. 185. Photographic copy of original construction drawing dated March 28, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    185. Photographic copy of original construction drawing dated March 28, 1932 (from Record Group 115, Denver Branch of the National Archives, Denver). VOLUME CHANGE IN MASS CONCRETE; OWYHEE DAM CONCRETE RESEARCH FOR HOOVER DAM; CONTRACTION JOINT METER INSTALLATION. - Owyhee Dam, Across Owyhee River, Nyssa, Malheur County, OR

  9. 18 CFR 367.1850 - Account 185, Temporary facilities.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... facilities. 367.1850 Section 367.1850 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE PUBLIC UTILITY HOLDING COMPANY ACT OF 2005, FEDERAL... ACT Balance Sheet Chart of Accounts Deferred Debits § 367.1850 Account 185, Temporary facilities....

  10. 18 CFR 367.1850 - Account 185, Temporary facilities.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... facilities. 367.1850 Section 367.1850 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE PUBLIC UTILITY HOLDING COMPANY ACT OF 2005, FEDERAL... ACT Balance Sheet Chart of Accounts Deferred Debits § 367.1850 Account 185, Temporary facilities....

  11. 18 CFR 367.1850 - Account 185, Temporary facilities.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... facilities. 367.1850 Section 367.1850 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE PUBLIC UTILITY HOLDING COMPANY ACT OF 2005, FEDERAL... ACT Balance Sheet Chart of Accounts Deferred Debits § 367.1850 Account 185, Temporary facilities....

  12. 18 CFR 367.1850 - Account 185, Temporary facilities.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... facilities. 367.1850 Section 367.1850 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE PUBLIC UTILITY HOLDING COMPANY ACT OF 2005, FEDERAL... ACT Balance Sheet Chart of Accounts Deferred Debits § 367.1850 Account 185, Temporary facilities....

  13. 18 CFR 367.1850 - Account 185, Temporary facilities.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... facilities. 367.1850 Section 367.1850 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE PUBLIC UTILITY HOLDING COMPANY ACT OF 2005, FEDERAL... ACT Balance Sheet Chart of Accounts Deferred Debits § 367.1850 Account 185, Temporary facilities....

  14. 40 CFR 421.185 - Pretreatment standards for existing sources.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Secondary Germanium and Gallium Subcategory § 421.185 Pretreatment standards for existing sources. Except as provided in 40 CFR 403.7 and 403.13, any existing source subject to this subpart which introduces pollutants into a publicly owned treatment works must comply with 40 CFR part 403 and achieve the...

  15. 40 CFR 421.185 - Pretreatment standards for existing sources.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Secondary Germanium and Gallium Subcategory § 421.185 Pretreatment standards for existing sources. Except as provided in 40 CFR 403.7 and 403.13, any existing source subject to this subpart which introduces pollutants into a publicly owned treatment works must comply with 40 CFR part 403 and achieve the...

  16. 40 CFR 421.185 - Pretreatment standards for existing sources.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Secondary Germanium and Gallium Subcategory § 421.185 Pretreatment standards for existing sources. Except as provided in 40 CFR 403.7 and 403.13, any existing source subject to this subpart which introduces pollutants into a publicly owned treatment works must comply with 40 CFR part 403 and achieve the...

  17. 16 CFR 1.85 - Final environmental impact statements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 16 Commercial Practices 1 2013-01-01 2013-01-01 false Final environmental impact statements. 1.85... Final environmental impact statements. (a) After the close of the comment period, the Bureau responsible for the matter will consider the comments received on the draft environmental impact statement...

  18. 16 CFR 1.85 - Final environmental impact statements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 16 Commercial Practices 1 2014-01-01 2014-01-01 false Final environmental impact statements. 1.85... Final environmental impact statements. (a) After the close of the comment period, the Bureau responsible for the matter will consider the comments received on the draft environmental impact statement...

  19. 16 CFR 1.85 - Final environmental impact statements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Final environmental impact statements. 1.85... Final environmental impact statements. (a) After the close of the comment period, the Bureau responsible for the matter will consider the comments received on the draft environmental impact statement...

  20. 16 CFR 1.85 - Final environmental impact statements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 1 2011-01-01 2011-01-01 false Final environmental impact statements. 1.85... Final environmental impact statements. (a) After the close of the comment period, the Bureau responsible for the matter will consider the comments received on the draft environmental impact statement...

  1. 16 CFR 1.85 - Final environmental impact statements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 1 2012-01-01 2012-01-01 false Final environmental impact statements. 1.85... Final environmental impact statements. (a) After the close of the comment period, the Bureau responsible for the matter will consider the comments received on the draft environmental impact statement...

  2. 32 CFR 185.2 - Applicability and scope.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... support civilian authorities during civil emergencies arising during peace, war, or transition to war. (e... National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE CIVIL DEFENSE MILITARY SUPPORT TO CIVIL AUTHORITIES (MSCA) § 185.2 Applicability and scope. This part: (a) Applies to the Office of...

  3. 32 CFR 185.2 - Applicability and scope.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE CIVIL DEFENSE DEFENSE SUPPORT OF CIVIL AUTHORITIES (DSCA) § 185.2 Applicability and scope. This part: (a) Applies to the Office of the... and Primary Agency for Emergency Support Function #3, Public Works and Engineering, of the...

  4. 32 CFR 185.2 - Applicability and scope.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE CIVIL DEFENSE DEFENSE SUPPORT OF CIVIL AUTHORITIES (DSCA) § 185.2 Applicability and scope. This part: (a) Applies to the Office of the... and Primary Agency for Emergency Support Function #3, Public Works and Engineering, of the...

  5. 32 CFR 185.2 - Applicability and scope.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE CIVIL DEFENSE DEFENSE SUPPORT OF CIVIL AUTHORITIES (DSCA) § 185.2 Applicability and scope. This part: (a) Applies to the Office of the... and Primary Agency for Emergency Support Function #3, Public Works and Engineering, of the...

  6. 32 CFR 185.2 - Applicability and scope.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE CIVIL DEFENSE DEFENSE SUPPORT OF CIVIL AUTHORITIES (DSCA) § 185.2 Applicability and scope. This part: (a) Applies to the Office of the... and Primary Agency for Emergency Support Function #3, Public Works and Engineering, of the...

  7. 40 CFR 792.185 - Reporting of study results.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., or other appropriate characteristics. (5) Stability, and when relevant to the conduct of the study... 40 Protection of Environment 33 2013-07-01 2013-07-01 false Reporting of study results. 792.185... study results. (a) A final report shall be prepared for each study and shall include, but...

  8. 40 CFR 792.185 - Reporting of study results.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., or other appropriate characteristics. (5) Stability, and when relevant to the conduct of the study... 40 Protection of Environment 33 2012-07-01 2012-07-01 false Reporting of study results. 792.185... study results. (a) A final report shall be prepared for each study and shall include, but...

  9. 40 CFR 792.185 - Reporting of study results.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., or other appropriate characteristics. (5) Stability, and when relevant to the conduct of the study... 40 Protection of Environment 32 2014-07-01 2014-07-01 false Reporting of study results. 792.185... study results. (a) A final report shall be prepared for each study and shall include, but...

  10. 46 CFR 185.352 - Ventilation of gasoline machinery spaces.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Ventilation of gasoline machinery spaces. 185.352... machinery spaces. The mechanical exhaust for the ventilation of a gasoline machinery space, required by... sufficient to insure at least one complete change of air in the space served....

  11. 22 CFR 18.5 - Interpretative standards; advisory opinions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ..., either in interim or final form by the Office of Government Ethics and published at 5 CFR part 737. (b... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Interpretative standards; advisory opinions. 18... EMPLOYMENT CONFLICT OF INTEREST Applicable Rules § 18.5 Interpretative standards; advisory opinions. (a)...

  12. 22 CFR 18.5 - Interpretative standards; advisory opinions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., either in interim or final form by the Office of Government Ethics and published at 5 CFR part 737. (b... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Interpretative standards; advisory opinions. 18... EMPLOYMENT CONFLICT OF INTEREST Applicable Rules § 18.5 Interpretative standards; advisory opinions. (a)...

  13. Effect of Factor XIII-A G185T Polymorphism on Visual Prognosis after Photodynamic Therapy for Neovascular Macular Degeneration

    PubMed Central

    Parmeggiani, Francesco; Costagliola, Ciro; Semeraro, Francesco; Romano, Mario R; Rinaldi, Michele; Gallenga, Carla Enrica; Serino, Maria Luisa; Incorvaia, Carlo; D’Angelo, Sergio; De Nadai, Katia; Dell’Omo, Roberto; Russo, Andrea; Gemmati, Donato; Perri, Paolo

    2015-01-01

    Macular degenerations represent leading causes of central blindness or low vision in developed countries. Most of these severe visual disabilities are due to age-related macular degeneration (AMD) and pathologic myopia (PM), both of which are frequently complicated by subfoveal choroidal neovascularization (CNV). Photodynamic therapy with verteporfin (PDT-V) is still employed for CNV treatment in selected cases or in combined regimen. In Caucasian patients, the common polymorphism G185T of factor XIII-A gene (FXIII-A-G185T; rs5985) has been described as predictor of poor angiographic CNV responsiveness to PDT-V. Nevertheless, the prognostic implications of this pharmacogenetic determinant on long-term visual outcome after a PDT-V regimen have not been evaluated. We retrospectively selected Caucasian patients presenting with treatment-naive CNV and receiving standardized PDT-V protocol for two years. The study population included patients affected by subfoveal CNV secondary to AMD or PM. We assessed the correlations between the polymorphic allele T of FXIII-A-G185T and: (1) total number of photodynamic treatments; and (2) change in visual acuity from baseline to the end of the follow-up period. Considering a total study population of 412 patients with neovascular AMD or PM, the carriers of 185 T-allele of FXIII-A (GT or TT genotype) received a higher number of photodynamic treatments than patients without it (GG wild-type genotype) (p < 0.01; mean number of PDT-V: 5.51 vs. 3.76, respectively). Moreover, patients with 185 T-allele of FXIII-A had a more marked worsening of visual acuity at 24 months than those with the GG-185 wild genotype (p < 0.01; mean difference in logMAR visual acuity: 0.22 vs. 0.08, respectively). The present findings show that the G185T polymorphism of the FXIII-A gene is associated with significant differences in the long-term therapeutic outcomes of patients treated with standardized PDT-V protocol. The comprehensive appraisal of both anti

  14. Effect of Factor XIII-A G185T Polymorphism on Visual Prognosis after Photodynamic Therapy for Neovascular Macular Degeneration.

    PubMed

    Parmeggiani, Francesco; Costagliola, Ciro; Semeraro, Francesco; Romano, Mario R; Rinaldi, Michele; Gallenga, Carla Enrica; Serino, Maria Luisa; Incorvaia, Carlo; D'Angelo, Sergio; De Nadai, Katia; Dell'Omo, Roberto; Russo, Andrea; Gemmati, Donato; Perri, Paolo

    2015-01-01

    Macular degenerations represent leading causes of central blindness or low vision in developed countries. Most of these severe visual disabilities are due to age-related macular degeneration (AMD) and pathologic myopia (PM), both of which are frequently complicated by subfoveal choroidal neovascularization (CNV). Photodynamic therapy with verteporfin (PDT-V) is still employed for CNV treatment in selected cases or in combined regimen. In Caucasian patients, the common polymorphism G185T of factor XIII-A gene (FXIII-A-G185T; rs5985) has been described as predictor of poor angiographic CNV responsiveness to PDT-V. Nevertheless, the prognostic implications of this pharmacogenetic determinant on long-term visual outcome after a PDT-V regimen have not been evaluated. We retrospectively selected Caucasian patients presenting with treatment-naive CNV and receiving standardized PDT-V protocol for two years. The study population included patients affected by subfoveal CNV secondary to AMD or PM. We assessed the correlations between the polymorphic allele T of FXIII-A-G185T and: (1) total number of photodynamic treatments; and (2) change in visual acuity from baseline to the end of the follow-up period. Considering a total study population of 412 patients with neovascular AMD or PM, the carriers of 185 T-allele of FXIII-A (GT or TT genotype) received a higher number of photodynamic treatments than patients without it (GG wild-type genotype) (p < 0.01; mean number of PDT-V: 5.51 vs. 3.76, respectively). Moreover, patients with 185 T-allele of FXIII-A had a more marked worsening of visual acuity at 24 months than those with the GG-185 wild genotype (p < 0.01; mean difference in logMAR visual acuity: 0.22 vs. 0.08, respectively). The present findings show that the G185T polymorphism of the FXIII-A gene is associated with significant differences in the long-term therapeutic outcomes of patients treated with standardized PDT-V protocol. The comprehensive appraisal of both anti

  15. 14 CFR 21.185 - Issue of airworthiness certificates for restricted category aircraft.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Issue of airworthiness certificates for restricted category aircraft. 21.185 Section 21.185 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... Certificates § 21.185 Issue of airworthiness certificates for restricted category aircraft. Link to...

  16. 40 CFR 436.185 - Standards of performance for new sources.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 30 2014-07-01 2014-07-01 false Standards of performance for new sources. 436.185 Section 436.185 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS (CONTINUED) MINERAL MINING AND PROCESSING POINT SOURCE CATEGORY Phosphate Rock Subcategory § 436.185 Standards...

  17. 41 CFR 102-85.185 - Can space be exempted from the standard levels of service

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false Can space be exempted from the standard levels of service 102-85.185 Section 102-85.185 Public Contracts and Property... PROPERTY 85-PRICING POLICY FOR OCCUPANCY IN GSA SPACE Standard Levels of Service § 102-85.185 Can space...

  18. 46 CFR 185.320 - Steering gear, controls, and communication system tests.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Steering gear, controls, and communication system tests. 185.320 Section 185.320 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Miscellaneous Operating Requirements § 185.320 Steering gear, controls, and communication...

  19. 42 CFR 440.185 - Respiratory care for ventilator-dependent individuals.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 4 2011-10-01 2011-10-01 false Respiratory care for ventilator-dependent individuals. 440.185 Section 440.185 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS SERVICES: GENERAL PROVISIONS Definitions § 440.185 Respiratory care...

  20. 5 CFR 185.128 - Form, filing and service of papers.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Form, filing and service of papers. 185.128 Section 185.128 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.128 Form, filing and service of papers. (a) Form. Documents filed with the ALJ shall include an original and...

  1. 20 CFR 402.185 - Waiver or reduction of fees in the public interest.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false Waiver or reduction of fees in the public interest. 402.185 Section 402.185 Employees' Benefits SOCIAL SECURITY ADMINISTRATION AVAILABILITY OF INFORMATION AND RECORDS TO THE PUBLIC § 402.185 Waiver or reduction of fees in the public interest....

  2. 20 CFR 402.185 - Waiver or reduction of fees in the public interest.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false Waiver or reduction of fees in the public interest. 402.185 Section 402.185 Employees' Benefits SOCIAL SECURITY ADMINISTRATION AVAILABILITY OF INFORMATION AND RECORDS TO THE PUBLIC § 402.185 Waiver or reduction of fees in the public interest....

  3. 20 CFR 402.185 - Waiver or reduction of fees in the public interest.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Waiver or reduction of fees in the public interest. 402.185 Section 402.185 Employees' Benefits SOCIAL SECURITY ADMINISTRATION AVAILABILITY OF INFORMATION AND RECORDS TO THE PUBLIC § 402.185 Waiver or reduction of fees in the public interest....

  4. 20 CFR 402.185 - Waiver or reduction of fees in the public interest.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Waiver or reduction of fees in the public interest. 402.185 Section 402.185 Employees' Benefits SOCIAL SECURITY ADMINISTRATION AVAILABILITY OF INFORMATION AND RECORDS TO THE PUBLIC § 402.185 Waiver or reduction of fees in the public interest....

  5. 20 CFR 402.185 - Waiver or reduction of fees in the public interest.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Waiver or reduction of fees in the public interest. 402.185 Section 402.185 Employees' Benefits SOCIAL SECURITY ADMINISTRATION AVAILABILITY OF INFORMATION AND RECORDS TO THE PUBLIC § 402.185 Waiver or reduction of fees in the public interest....

  6. 21 CFR 58.185 - Reporting of nonclinical laboratory study results.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Reporting of nonclinical laboratory study results. 58.185 Section 58.185 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL GOOD LABORATORY PRACTICE FOR NONCLINICAL LABORATORY STUDIES Records and Reports § 58.185 Reporting of nonclinical laboratory...

  7. 5 CFR 185.103 - Basis for civil penalties and assessments.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Basis for civil penalties and assessments. 185.103 Section 185.103 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.103 Basis for civil penalties and assessments. (a) In...

  8. 42 CFR 416.185 - Process for establishing a new class of new technology IOLs.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... technology IOLs. 416.185 Section 416.185 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT... Adjustment in Payment Amounts for New Technology Intraocular Lenses Furnished by Ambulatory Service Centers § 416.185 Process for establishing a new class of new technology IOLs. (a) Announcement of deadline...

  9. 42 CFR 416.185 - Process for establishing a new class of new technology IOLs.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... technology IOLs. 416.185 Section 416.185 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT... Adjustment in Payment Amounts for New Technology Intraocular Lenses Furnished by Ambulatory Service Centers § 416.185 Process for establishing a new class of new technology IOLs. (a) Announcement of deadline...

  10. 46 CFR 185.212 - Mandatory chemical testing following serious marine incidents.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Mandatory chemical testing following serious marine incidents. 185.212 Section 185.212 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Marine Casualties and Voyage Records § 185.212 Mandatory chemical testing following...

  11. 46 CFR 185.220 - Records of a voyage resulting in a marine casualty.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Records of a voyage resulting in a marine casualty. 185.220 Section 185.220 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Marine Casualties and Voyage Records § 185.220 Records of a voyage resulting in a marine casualty....

  12. 46 CFR 185.220 - Records of a voyage resulting in a marine casualty.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Records of a voyage resulting in a marine casualty. 185.220 Section 185.220 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Marine Casualties and Voyage Records § 185.220 Records of a voyage resulting in a marine casualty....

  13. 42 CFR 416.185 - Process for establishing a new class of new technology IOLs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... technology IOLs. 416.185 Section 416.185 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT... Payment Amounts for New Technology Intraocular Lenses Furnished by Ambulatory Service Centers § 416.185 Process for establishing a new class of new technology IOLs. (a) Announcement of deadline for requests...

  14. 12 CFR 303.185 - Merger transactions involving foreign banks or foreign organizations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Merger transactions involving foreign banks or foreign organizations. 303.185 Section 303.185 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION PROCEDURE AND RULES OF PRACTICE FILING PROCEDURES International Banking § 303.185 Merger...

  15. 46 CFR 185.730 - Servicing of inflatable liferafts, inflatable buoyant apparatus, inflatable life jackets, and...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... inflatable liferaft or inflatable buoyant apparatus must be serviced at a facility specifically approved by... apparatus, inflatable life jackets, and inflated rescue boats. 185.730 Section 185.730 Shipping COAST GUARD... Operational Readiness, Maintenance, and Inspection of Lifesaving Equipment § 185.730 Servicing of...

  16. 46 CFR 185.730 - Servicing of inflatable liferafts, inflatable buoyant apparatus, inflatable life jackets, and...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... inflatable liferaft or inflatable buoyant apparatus must be serviced at a facility specifically approved by... apparatus, inflatable life jackets, and inflated rescue boats. 185.730 Section 185.730 Shipping COAST GUARD... Operational Readiness, Maintenance, and Inspection of Lifesaving Equipment § 185.730 Servicing of...

  17. 5 CFR 185.145 - Deposit in Treasury of the United States.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Deposit in Treasury of the United States. 185.145 Section 185.145 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.145 Deposit in Treasury of the United States. All...

  18. 5 CFR 185.143 - Collection of civil penalties and assessments.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Collection of civil penalties and assessments. 185.143 Section 185.143 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.143 Collection of civil penalties and assessments....

  19. 5 CFR 185.111 - Referral of complaint and answer to the ALJ.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Referral of complaint and answer to the ALJ. 185.111 Section 185.111 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.111 Referral of complaint and answer to the ALJ. Upon...

  20. 5 CFR 185.103 - Basis for civil penalties and assessments.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Basis for civil penalties and assessments. 185.103 Section 185.103 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.103 Basis for civil penalties and assessments. (a) In...

  1. 5 CFR 185.110 - Default upon failure to file an answer.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Default upon failure to file an answer. 185.110 Section 185.110 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.110 Default upon failure to file an answer. (a) If...

  2. 5 CFR 185.123 - Exchange of witness lists, statements and exhibits.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Exchange of witness lists, statements and exhibits. 185.123 Section 185.123 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.123 Exchange of witness lists, statements and exhibits. (a)...

  3. Screening for 185delAG in the Ashkenazim.

    PubMed Central

    Richards, C S; Ward, P A; Roa, B B; Friedman, L C; Boyd, A A; Kuenzli, G; Dunn, J K; Plon, S E

    1997-01-01

    A study was initiated to assess interest, educational effectiveness, and implications of genetic testing for the common BRCA1 mutation, 185delAG, in the Ashkenazim. Of 333 individuals who attended group sessions, 309 (92%) participated in the study. Participants were categorized as having negative family history (67%), positive family history (defined, by a relaxed criterion, as one first-degree relative or two second-degree relatives with breast [premenopausal] or ovarian cancer) (22%), positive personal history (7%), and both positive personal history and positive family history (4%). Group education was effective, as shown by the improvement in participant scores from pre- to posteducation tests. For the 289 individuals (94%) who requested testing, the major reasons included concern for their own risk, concern for the risk of their children, and desire to learn about surveillance options. The most common reason given by participants who declined testing was concern about health insurance. Six participants found to be heterozygous for the 185delAG mutation received results and were offered genetic counseling. Participants had consented for additional testing without receiving results and were screened for the 6174delT mutation in BRCA2, and seven were found to be positive. All identified carriers reported at least one first- or second-degree relative with a history of breast or ovarian cancer, although they did not all meet our study criteria for positive family history. Given these outcomes, we conclude that screening for breast and ovarian cancer susceptibility is most appropriate for individuals with a positive personal or positive family cancer history. We propose a guideline for future studies designed to identify individuals who may benefit from genetic testing for inherited breast and ovarian cancer. Images Figure 1 PMID:9150156

  4. Where Will LEAD Lead?

    ERIC Educational Resources Information Center

    Wildman, Louis

    After setting forth eight assumptions concerning the education of educational administrators, findings about the Leadership in Educational Administration Development (LEAD) program are discussed. The analysis is based on the first-year applications, telephone conversations with staff at a majority of the project sites, and additional material…

  5. LEADING WITH LEADING INDICATORS

    SciTech Connect

    PREVETTE, S.S.

    2005-01-27

    This paper documents Fluor Hanford's use of Leading Indicators, management leadership, and statistical methodology in order to improve safe performance of work. By applying these methods, Fluor Hanford achieved a significant reduction in injury rates in 2003 and 2004, and the improvement continues today. The integration of data, leadership, and teamwork pays off with improved safety performance and credibility with the customer. The use of Statistical Process Control, Pareto Charts, and Systems Thinking and their effect on management decisions and employee involvement are discussed. Included are practical examples of choosing leading indicators. A statistically based color coded dashboard presentation system methodology is provided. These tools, management theories and methods, coupled with involved leadership and employee efforts, directly led to significant improvements in worker safety and health, and environmental protection and restoration at one of the nation's largest nuclear cleanup sites.

  6. The Structures of the C185S and C185A Mutants of Sulfite Oxidase Reveal Rearrangement of the Active Site

    SciTech Connect

    Qiu, James A.; Wilson, Heather L.; Pushie, M. Jake; Kisker, Caroline; George, Graham N.; Rajagopalan, K.V.

    2010-11-03

    Sulfite oxidase (SO) catalyzes the physiologically critical conversion of sulfite to sulfate. Enzymatic activity is dependent on the presence of the metal molybdenum complexed with a pyranopterin-dithiolene cofactor termed molybdopterin. Comparison of the amino acid sequences of SOs from a variety of sources has identified a single conserved Cys residue essential for catalytic activity. The crystal structure of chicken liver sulfite oxidase indicated that this residue, Cys185 in chicken SO, coordinates the Mo atom in the active site. To improve our understanding of the role of this residue in the catalytic mechanism of sulfite oxidase, serine and alanine variants at position 185 of recombinant chicken SO were generated. Spectroscopic and kinetic studies indicate that neither variant is capable of sulfite oxidation. The crystal structure of the C185S variant was determined to 1.9 {angstrom} resolution and to 2.4 {angstrom} resolution in the presence of sulfite, and the C185A variant to 2.8 {angstrom} resolution. The structures of the C185S and C185A variants revealed that neither the Ser or Ala side chains appeared to closely interact with the Mo atom and that a third oxo group replaced the usual cysteine sulfur ligand at the Mo center, confirming earlier extended X-ray absorption fine structure spectroscopy (EXAFS) work on the human C207S mutant. An unexpected result was that in the C185S variant, in the absence of sulfite, the active site residue Tyr322 became disordered as did the loop region flanking it. In the C185S variant crystallized in the presence of sulfite, the Tyr322 residue relocalized to the active site. The C185A variant structure also indicated the presence of a third oxygen ligand; however, Tyr322 remained in the active site. EXAFS studies of the Mo coordination environment indicate the Mo atom is in the oxidized Mo{sup VI} state in both the C185S and C185A variants of chicken SO and show the expected trioxodithiolene active site. Density

  7. 41 CFR 102-3.185 - What does this subpart require agencies to do?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 41 Public Contracts and Property Management 3 2012-01-01 2012-01-01 false What does this subpart require agencies to do? 102-3.185 Section 102-3.185 Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION GENERAL 3-FEDERAL...

  8. 41 CFR 102-3.185 - What does this subpart require agencies to do?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false What does this subpart require agencies to do? 102-3.185 Section 102-3.185 Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION GENERAL 3-FEDERAL...

  9. 40 CFR 436.185 - Standards of performance for new sources.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 30 2011-07-01 2011-07-01 false Standards of performance for new sources. 436.185 Section 436.185 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS MINERAL MINING AND PROCESSING POINT SOURCE CATEGORY Phosphate...

  10. 20 CFR 655.185 - Job service complaint system; enforcement of work contracts.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Job service complaint system; enforcement of work contracts. 655.185 Section 655.185 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR TEMPORARY EMPLOYMENT OF FOREIGN WORKERS IN THE UNITED STATES Labor Certification Process for Temporary Agricultural Employment...

  11. 27 CFR 70.185 - Certificate of sale; deed of real property.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... of real property. 70.185 Section 70.185 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO... of sale; deed of real property. (a) Certificate of sale. In the case of property sold as provided in... puchaser's a certificate of sale upon payment in full of the purchase price. A certificate of sale of...

  12. 27 CFR 70.185 - Certificate of sale; deed of real property.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... of real property. 70.185 Section 70.185 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO... of sale; deed of real property. (a) Certificate of sale. In the case of property sold as provided in... puchaser's a certificate of sale upon payment in full of the purchase price. A certificate of sale of...

  13. 33 CFR 207.185 - Taylors Bayou, Tex., Beaumont Navigation District Lock; use, administration, and navigation.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 3 2012-07-01 2012-07-01 false Taylors Bayou, Tex., Beaumont Navigation District Lock; use, administration, and navigation. 207.185 Section 207.185 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE NAVIGATION...

  14. 33 CFR 207.185 - Taylors Bayou, Tex., Beaumont Navigation District Lock; use, administration, and navigation.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 3 2011-07-01 2011-07-01 false Taylors Bayou, Tex., Beaumont Navigation District Lock; use, administration, and navigation. 207.185 Section 207.185 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE NAVIGATION...

  15. 33 CFR 207.185 - Taylors Bayou, Tex., Beaumont Navigation District Lock; use, administration, and navigation.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 3 2014-07-01 2014-07-01 false Taylors Bayou, Tex., Beaumont Navigation District Lock; use, administration, and navigation. 207.185 Section 207.185 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE NAVIGATION...

  16. 33 CFR 207.185 - Taylors Bayou, Tex., Beaumont Navigation District Lock; use, administration, and navigation.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 3 2013-07-01 2013-07-01 false Taylors Bayou, Tex., Beaumont Navigation District Lock; use, administration, and navigation. 207.185 Section 207.185 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE NAVIGATION...

  17. 46 CFR 185.230 - Report of accident to aid to navigation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Report of accident to aid to navigation. 185.230 Section 185.230 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS... aid to navigation. Whenever a vessel collides with a buoy, or other aid to navigation under...

  18. 46 CFR 185.230 - Report of accident to aid to navigation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Report of accident to aid to navigation. 185.230 Section 185.230 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS... aid to navigation. Whenever a vessel collides with a buoy, or other aid to navigation under...

  19. 46 CFR 185.230 - Report of accident to aid to navigation.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Report of accident to aid to navigation. 185.230 Section 185.230 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS... aid to navigation. Whenever a vessel collides with a buoy, or other aid to navigation under...

  20. 46 CFR 185.230 - Report of accident to aid to navigation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Report of accident to aid to navigation. 185.230 Section 185.230 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS... aid to navigation. Whenever a vessel collides with a buoy, or other aid to navigation under...

  1. 46 CFR 185.230 - Report of accident to aid to navigation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Report of accident to aid to navigation. 185.230 Section 185.230 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS... aid to navigation. Whenever a vessel collides with a buoy, or other aid to navigation under...

  2. 33 CFR 207.185 - Taylors Bayou, Tex., Beaumont Navigation District Lock; use, administration, and navigation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Taylors Bayou, Tex., Beaumont Navigation District Lock; use, administration, and navigation. 207.185 Section 207.185 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE NAVIGATION...

  3. 21 CFR 58.185 - Reporting of nonclinical laboratory study results.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    .... 58.185 Section 58.185 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN... shall include the number of animals used, sex, body weight range, source of supply, species, strain and..., chemical abstracts number or code number, strength, purity, and composition or other...

  4. 21 CFR 58.185 - Reporting of nonclinical laboratory study results.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    .... 58.185 Section 58.185 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN... shall include the number of animals used, sex, body weight range, source of supply, species, strain and..., chemical abstracts number or code number, strength, purity, and composition or other...

  5. 21 CFR 58.185 - Reporting of nonclinical laboratory study results.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    .... 58.185 Section 58.185 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN... shall include the number of animals used, sex, body weight range, source of supply, species, strain and..., chemical abstracts number or code number, strength, purity, and composition or other...

  6. 21 CFR 58.185 - Reporting of nonclinical laboratory study results.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    .... 58.185 Section 58.185 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN... shall include the number of animals used, sex, body weight range, source of supply, species, strain and..., chemical abstracts number or code number, strength, purity, and composition or other...

  7. 24 CFR 990.185 - Utilities expense level: Incentives for energy conservation/rate reduction.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 4 2012-04-01 2012-04-01 false Utilities expense level: Incentives for energy conservation/rate reduction. 990.185 Section 990.185 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN DEVELOPMENT (CONTINUED) OFFICE OF ASSISTANT SECRETARY FOR PUBLIC AND INDIAN HOUSING, DEPARTMENT OF HOUSING...

  8. 41 CFR 102-85.185 - Can space be exempted from the standard levels of service

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Can space be exempted from the standard levels of service 102-85.185 Section 102-85.185 Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION REAL PROPERTY 85-PRICING POLICY FOR OCCUPANCY IN...

  9. 7 CFR 800.185 - Duties of official personnel and warehouse samplers.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 7 2011-01-01 2011-01-01 false Duties of official personnel and warehouse samplers. 800.185 Section 800.185 Agriculture Regulations of the Department of Agriculture (Continued) GRAIN INSPECTION, PACKERS AND STOCKYARD ADMINISTRATION (FEDERAL GRAIN INSPECTION SERVICE), DEPARTMENT OF AGRICULTURE GENERAL REGULATIONS Duties and Conduct...

  10. 5 CFR 185.128 - Form, filing and service of papers.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ....128 Section 185.128 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.128 Form, filing and service of papers. (a) Form. Documents filed with the ALJ shall include an original and two copies. Every pleading and paper filed in the...

  11. 46 CFR 185.212 - Mandatory chemical testing following serious marine incidents.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Mandatory chemical testing following serious marine incidents. 185.212 Section 185.212 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL... chemical testing following serious marine incidents. A marine employer whose vessel is involved in...

  12. 40 CFR 436.185 - Standards of performance for new sources.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 29 2010-07-01 2010-07-01 false Standards of performance for new sources. 436.185 Section 436.185 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS MINERAL MINING AND PROCESSING POINT SOURCE CATEGORY Phosphate...

  13. 47 CFR 90.185 - Multiple licensing of radio transmitting equipment in the mobile radio service.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Multiple licensing of radio transmitting equipment in the mobile radio service. 90.185 Section 90.185 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES PRIVATE LAND MOBILE RADIO SERVICES...

  14. 47 CFR 90.185 - Multiple licensing of radio transmitting equipment in the mobile radio service.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 5 2014-10-01 2014-10-01 false Multiple licensing of radio transmitting equipment in the mobile radio service. 90.185 Section 90.185 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES PRIVATE LAND MOBILE RADIO SERVICES...

  15. 47 CFR 90.185 - Multiple licensing of radio transmitting equipment in the mobile radio service.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 5 2012-10-01 2012-10-01 false Multiple licensing of radio transmitting equipment in the mobile radio service. 90.185 Section 90.185 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES PRIVATE LAND MOBILE RADIO SERVICES...

  16. 47 CFR 90.185 - Multiple licensing of radio transmitting equipment in the mobile radio service.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Multiple licensing of radio transmitting equipment in the mobile radio service. 90.185 Section 90.185 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES PRIVATE LAND MOBILE RADIO SERVICES...

  17. 47 CFR 90.185 - Multiple licensing of radio transmitting equipment in the mobile radio service.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 5 2013-10-01 2013-10-01 false Multiple licensing of radio transmitting equipment in the mobile radio service. 90.185 Section 90.185 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES PRIVATE LAND MOBILE RADIO SERVICES...

  18. 41 CFR 102-3.185 - What does this subpart require agencies to do?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false What does this subpart require agencies to do? 102-3.185 Section 102-3.185 Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION GENERAL 3-FEDERAL...

  19. 46 CFR 185.614 - Portable watertight containers for distress flares and smoke signals.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... smoke signals. 185.614 Section 185.614 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED... watertight containers for distress flares and smoke signals. Portable watertight containers for distress flares and smoke signals shall be of a bright color, and containers shall be clearly marked in...

  20. 46 CFR 185.614 - Portable watertight containers for distress flares and smoke signals.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... smoke signals. 185.614 Section 185.614 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED... watertight containers for distress flares and smoke signals. Portable watertight containers for distress flares and smoke signals shall be of a bright color, and containers shall be clearly marked in...

  1. 46 CFR 185.614 - Portable watertight containers for distress flares and smoke signals.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... smoke signals. 185.614 Section 185.614 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED... watertight containers for distress flares and smoke signals. Portable watertight containers for distress flares and smoke signals shall be of a bright color, and containers shall be clearly marked in...

  2. 46 CFR 185.614 - Portable watertight containers for distress flares and smoke signals.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... smoke signals. 185.614 Section 185.614 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED... watertight containers for distress flares and smoke signals. Portable watertight containers for distress flares and smoke signals shall be of a bright color, and containers shall be clearly marked in...

  3. 46 CFR 185.614 - Portable watertight containers for distress flares and smoke signals.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... smoke signals. 185.614 Section 185.614 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED... watertight containers for distress flares and smoke signals. Portable watertight containers for distress flares and smoke signals shall be of a bright color, and containers shall be clearly marked in...

  4. 46 CFR 185.728 - Testing and servicing of Emergency Position Indicating Radiobeacons (EPIRB).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Testing and servicing of Emergency Position Indicating Radiobeacons (EPIRB). 185.728 Section 185.728 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Operational Readiness, Maintenance, and Inspection of Lifesaving Equipment...

  5. 46 CFR 185.728 - Testing and servicing of Emergency Position Indicating Radiobeacons (EPIRB).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Testing and servicing of Emergency Position Indicating Radiobeacons (EPIRB). 185.728 Section 185.728 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Operational Readiness, Maintenance, and Inspection of Lifesaving Equipment...

  6. 36 CFR 18.5 - May property be leased without receiving fair market value rent?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... without receiving fair market value rent? 18.5 Section 18.5 Parks, Forests, and Public Property NATIONAL... leased without receiving fair market value rent? Property may be leased under this part only if the lease requires payment of rent to the government equal to or higher than the property's fair market value...

  7. 5 CFR 185.133 - Determining the amount of penalties and assessments.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Determining the amount of penalties and assessments. 185.133 Section 185.133 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE... public confidence in the management of Government programs and operations; (8) Whether the defendant...

  8. 5 CFR 185.140 - Stays ordered by the Department of Justice.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Stays ordered by the Department of Justice. 185.140 Section 185.140 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE... the authority head a written finding that continuation of the administrative process described in...

  9. Probiotic Characteristics of Lactobacillus plantarum FH185 Isolated from Human Feces

    PubMed Central

    2015-01-01

    Lactobacillus plantarum FH185 was isolated from the feces of healthy adults. In our previous study, L. plantarum FH185 was demonstrated that it has anti-obesity effect in the in vitro and in vivo test. In order to determine its potential for use as a probiotic, we investigated the physiological characteristics of L. plantarum FH185. The optimum growth temperature of L. plantarum FH185 was 40℃. L. plantarum FH185 showed higher sensitivity to novobiocin in a comparison of fifteen different antibiotics and showed higher resistance to polymyxin B and vancomycin. It also showed higher β-galactosidase and N-acetyl-β-glucosaminidase activities. Moreover, it was comparatively tolerant to bile juice and acid, and inhibited the growths of Salmonella Typhimurium and Staphylococcus aureus with rates of 44.76% and 53.88%, respectively. It also showed high adhesion activity to HT-29 cells compared to L. rhamnosus GG. PMID:26761889

  10. Semantic similarity: normative ratings for 185 Spanish noun triplets.

    PubMed

    Moldovan, Cornelia D; Ferré, Pilar; Demestre, Josep; Sánchez-Casas, Rosa

    2015-09-01

    The present study introduces the first Spanish database with normative ratings of semantic similarity for 185 word triplets. Each word triplet is constituted by a target word (e.g., guisante [pea]) and two semantically related and nonassociatively related words: a word highly related in meaning to the target (e.g., judía [bean]), and a word less related in meaning to the target (e.g., patata [potato]). The degree of meaning similarity was assessed by 332 participants by using a semantic similarity rating task on a 9-point scale. Pairs having a value of semantic similarity ranging from 5 to 9 were classified as being more semantically related, whereas those with values ranging from 2 to 4.99 were considered as being less semantically related. The relative distance between the two pairs for the same target ranged from 0.48 to 5.07 points. Mean comparisons revealed that participants rated the more similar words as being significantly more similar in meaning to the target word than were the less similar words. In addition to the semantic similarity norms, values of concreteness and familiarity of each word in a triplet are provided. The present database can be a very useful tool for scientists interested in designing experiments to examine the role of semantics in language processing. Since the variable of semantic similarity includes a wide range of values, it can be used as either a continuous or a dichotomous variable. The full database is available in the supplementary materials. PMID:24984982

  11. Mechanism of cyanoacetylene photochemistry at 185 and 254 nm

    NASA Technical Reports Server (NTRS)

    Clarke, D. W.; Ferris, J. P.

    1996-01-01

    The role of cyanoacetylene (HC3N) in the atmospheric photochemistry of Titan and its relevance to polymer formation are discussed. Investigation of the relative light absorption of HC3N, acetylene (C2H2), and diacetylene (C4H2) revealed that HC3N is an important absorber of UV light in the 205- to 225-nanometer wavelength region in Titan's polar regions. Laboratory studies established that photolysis of C2H2 initiates the polymerization of HC3N even though the HC3N is not absorbing the UV light. Quantum yield measurements establish that HC3N is 2-5 times as reactive as C2H2 for polymer formation. Photolysis of HC3N with 185-nanometer light in the presence of N2, H2, Ar, or CF4 results in a decrease in the yield of 1,3,5-tricyanobenzene (1,3,5-tcb), while photolysis in the presence of CH4, C2H6, or n-C4H10 results in an increase in 1,3,5-tcb. The rate of loss of HC3N is increased by all gases except H2, where it is unchanged. It was not possible to detect 1,3,5-tcb as a photoproduct when the partial pressure of HC3N was decreased to 1 torr. Photolysis of HC3N with 254-nanometer light in the presence of H2 or N2 results in the formation of 1,2,4-tcb, while photolysis in the presence of CH4, C2H6, or n-C4H10 results in the formation of increasing amounts of 1,3,5-tcb. Mechanisms for the formation of polymers are presented.

  12. Lead Poisoning

    MedlinePlus

    ... Experiments Stories Lessons Topics Games Activities Lessons MENU Lead Poisoning Kids Homepage Topics Pollution Lead Poisoning What is ... you can avoid contact with it! Sources of Lead Poisoning HOUSE PAINTS: Before1950, lead-based paint was used ...

  13. Lead Test

    MedlinePlus

    ... to determine lead sources, educating family members about lead poisoning , and instituting follow-up testing to monitor the ... high levels of lead, see the article on Lead Poisoning . The Occupational Safety and Health Administration (OSHA) has ...

  14. Lead Poisoning

    MedlinePlus

    Lead Poisoning What is it and who is affected? Lead is a highly toxic substance, exposure to which ... and children can suffer from the effects of lead poisoning, but childhood lead poisoning is much more frequent. ...

  15. Molecular basis of preferential resistance to colchicine in multidrug-resistant human cells conferred by Gly-185 yields Val-185 substitution in P-glycoprotein

    SciTech Connect

    Safa, A.R.; Stern, R.K.; Choi, Kyunghee; Agresti, M.; Tamai, Ikumi; Mehta, N.D.; Roninson, I.B. )

    1990-09-01

    Expression of P-glycoprotein, encoded by the human MDR1 gene, results in cross-resistance to many lipophilic cytotoxic drugs (multidrug resistance). P-glycoprotein is believed to function as an energy-dependent efflux pump that is responsible for decreased drug accumulation in multidrug-resistant cells. Previous work showed that preferential resistance to colchicine in a colchicine-selected multidrug-resistant cell line was caused by spontaneous mutations in the MDR1 gene that resulted in a Gly-185 {yields} Val-185 substitution in P-glycoprotein. The authors have now compared transfectant cell lines expressing the wild-type Gly-185 or the mutant Val-185 P-glycoprotein with regard to their levels of resistance to and accumulation and binding of different drugs. In cells expressing the mutant protein, increased resistance to colchicine and decreased resistance to vinblastine correlated with a decreased accumulation of colchicine and increased accumulation of vinblastine. Expression of the mutant P-glycoprotein also resulted in significantly increased resistance to epipodophyllotoxin and decreased resistance to vincristine and actinomycin D; smaller changes in resistance were observed for several other drugs. Unexpectedly, the mutant P-glycoprotein showed increased binding of photoactive analogs of vinblastine and verapamil and the photoactive compound azidopine and decreased binding of a photoactive colchicine analog. These results suggest that the Gly-185 {yields} Val-185 substitution affects not the initial drug-binding site of P-glycoprotein but another site, associated with the release of P-glycoprotein-bound drugs to the outside of the cell.

  16. Evaluation of the roles of the A185C and C406T kinesin light-chain 1 variants in the development of leukoaraiosis.

    PubMed

    Szolnoki, Zoltan; Kondacs, Andras; Mandi, Yvette; Somogyvari, Ferenc

    2007-12-18

    Vascular white matter demyelinization of the brain is referred to as leukoaraiosis (LA). This frequent age-associated entity leads to a cognitive decline or dementia. The background of LA has been hypothesized to be a chronic hypoxia-induced functional cytoskeleton malfunction. Setting out from this assumption, we earlier found that the kinesin light-chain 1 (KNS2) cytoskeleton motor protein 56836CC single nucleotide polymorphism conferred a risk of LA in hypertensive smokers. The aim of the present study was to extend our observations as to how the KNS2 A185C and C406T single nucleotide polymorphisms in the 5'-untranslated sequence region affect the susceptibility to LA. These two latter variants were presumed to influence the transcription of the KNS2 mRNA by locating in a function-enhancer region. An association analysis of these genetic variants was conducted on 242 patients with LA and 251 neuroimaging alteration-free controls. The KNS2 AA185-406TT haplotype increased the risk of LA 3.56-fold in hypertensive smokers as compared with those not carrying the KNS2 AA185-406TT genotype, which was similar to our previous findings for the KNS2 56836CC intron variant. Moreover, the three homozygous KNS2 variants (56936CC-AA185-406TT) coincided to an extent of 82.2%. Overall, although the 56836CC intron variant appears to be the most important of the three kinesin variants as regards the development of LA, the contribution of the AA185-406TT haplotype to the unfavorable phenotype of LA cannot be ruled out. The present finding supports the involvement of the cytoskeleton in the development of vascular white matter damage, thereby opening up novel fields in the research into LA. PMID:17977659

  17. 49 CFR 40.185 - Through what methods and to whom must a laboratory report split specimen results?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Through what methods and to whom must a laboratory report split specimen results? 40.185 Section 40.185 Transportation Office of the Secretary of Transportation PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Split Specimen Tests § 40.185 Through what methods and to...

  18. 34 CFR 403.185 - How does the Secretary compute maintenance of effort in the event of a waiver?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false How does the Secretary compute maintenance of effort in the event of a waiver? 403.185 Section 403.185 Education Regulations of the Offices of the Department....185 How does the Secretary compute maintenance of effort in the event of a waiver? If a State has...

  19. 34 CFR 403.185 - How does the Secretary compute maintenance of effort in the event of a waiver?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 3 2011-07-01 2011-07-01 false How does the Secretary compute maintenance of effort in the event of a waiver? 403.185 Section 403.185 Education Regulations of the Offices of the Department....185 How does the Secretary compute maintenance of effort in the event of a waiver? If a State has...

  20. 34 CFR 403.185 - How does the Secretary compute maintenance of effort in the event of a waiver?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 3 2012-07-01 2012-07-01 false How does the Secretary compute maintenance of effort in the event of a waiver? 403.185 Section 403.185 Education Regulations of the Offices of the Department....185 How does the Secretary compute maintenance of effort in the event of a waiver? If a State has...

  1. Lead Poisoning

    MedlinePlus

    Lead is a metal that occurs naturally in the earth's crust. Lead can be found in all parts of our ... from human activities such as mining and manufacturing. Lead used to be in paint; older houses may ...

  2. Lead poisoning

    MedlinePlus

    ... swallows a lead object or breathes in lead dust, some of the poison can stay in the ... a health problem. Lead is everywhere, including dirt, dust, new toys, and old house paint. Unfortunately, you ...

  3. Lead Toxicity

    MedlinePlus

    ... homes. • Most people, especially children, who suffer from lead poisoning are exposed through lead-contaminated household dust or ... and six if they are at risk of lead poisoning (see: ). Who can I call to get more ...

  4. 185. WASHINGTON SKYLINE ACROSS POTOMAC RIVER FROM L.B.J. MEMORIAL PARK ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    185. WASHINGTON SKYLINE ACROSS POTOMAC RIVER FROM L.B.J. MEMORIAL PARK LOOKING NORTH EAST. - George Washington Memorial Parkway, Along Potomac River from McLean to Mount Vernon, VA, Mount Vernon, Fairfax County, VA

  5. 42 CFR 416.185 - Process for establishing a new class of new technology IOLs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Payment Amounts for New Technology Intraocular Lenses Furnished by Ambulatory Service Centers § 416.185... following calendar year. CMS publishes the codes and effective dates allowed for those lenses recognized...

  6. 1. 185/189D in center, north end west facades (190D front ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. 185/189-D in center, north end west facades (190-D front left and west facade; 195-D rear right). Looking south. - D-Reactor Complex, Deaeration Plant-Refrigeration Buildings, Area 100-D, Richland, Benton County, WA

  7. HIV-1 Nef binds with human GCC185 protein and regulates mannose 6 phosphate receptor recycling.

    PubMed

    Kumar, Manjeet; Kaur, Supinder; Nazir, Aamir; Tripathi, Raj Kamal

    2016-05-20

    HIV-1 Nef modulates cellular function that enhances viral replication in vivo which culminate into AIDS pathogenesis. With no enzymatic activity, Nef regulates cellular function through host protein interaction. Interestingly, trans-cellular introduction of recombinant Nef protein in Caenorhabditis elegans results in AIDS like pathogenesis which might share common pathophysiology because the gene sequence of C. elegans and humans share considerable homology. Therefore employing C. elegans based initial screen complemented with sequence based homology search we identified GCC185 as novel host protein interacting with HIV-1 Nef. The detailed molecular characterization revealed N-terminal EEEE65 acidic domain of Nef as key region for interaction. GCC185 is a tethering protein that binds with Rab9 transport vesicles. Our results show that Nef-GCC185 interaction disrupts Rab9 interaction resulting in delocalization of CI-MPR (cation independent Mannose 6 phosphate receptor) resulting in elevated secretion of hexosaminidase. In agreement with this, our studies identified novel host GCC185 protein that interacts with Nef EEEE65 acidic domain interfering GCC185-Rab9 vesicle membrane fusion responsible for retrograde vesicular transport of CI-MPR from late endosomes to TGN. In light of existing report suggesting critical role of Nef-GCC185 interaction reveals valuable mechanistic insights affecting specific protein transport pathway in docking of late endosome derived Rab9 bearing transport vesicle at TGN elucidating role of Nef during viral pathogenesis. PMID:27105913

  8. Lead Poisoning

    MedlinePlus

    ... our environment. Much of it comes from human activities such as mining and manufacturing. Lead used to be in paint; older houses may still have lead paint. You could be exposed to lead by Eating food or drinking water that contains lead. Water pipes in older homes ...

  9. Lead poisoning

    SciTech Connect

    Rekus, J.F.

    1992-08-01

    Construction workers who weld, cut or blast structural steel coated with lead-based paint are at significant risk of lead poisoning. Although technology to control these exposures may not have existed when the lead standard was promulgated, it is available today. Employers who do not take steps to protect their employees from lead exposure may be cited and fined severely for their failure.

  10. Isolation of immune-relating 185/333-1 gene from Sea Urchin ( Strongylocentrotus intermedius) and Its expression analysis

    NASA Astrophysics Data System (ADS)

    Wang, Yinan; Ding, Jun; Liu, Yang; Liu, Xuewei; Chang, Yaqing

    2016-02-01

    The 185/333 gene family involved in the immune response of sea urchin. One 185/333 cDNA was isolated from Strongylocentrotus intermedius, and named as Si185/333-1. Its full-length cDNA was 1246 bp in length with a 906 bp open reading frame encoding a protein of 301 aa. The molecular weight of the deduced protein was approximately 33.1 kD with an estimated PI of pH 6.26. Si185/333-1 had high identities (70%-86%) to most of Sp185/333. An extraordinary identity of 92% was found between Si185/333-1 and Sp185/333 C5 alpha (ABR22474). Moderate identities (63%-64%) were displayed between Si185/333-1 and He185/333. Si185/333-1 had similar structure to Sp185/333. A signal-peptide, a gly-rich region and a his-rich region were found in its secondary structure. RGD motif was found in gly-rich region at position 116-118aa. There was no transmembrane region in Si185/333-1. The element pattern of Si185/333-1 is different from any available pattern that identified in Sp185/333. Si185/333-1 clustered together with pattern C Sp185/333 in phylogenetic tree. The Si185/333-1 mRNA could be detected in tißsues including peristomial membrane, coelomocytes, muscle of Aristotles lantern, gut and tube feet, with the highest expression level detected in peristomial membrane and a relatively low expression in ovary and testis. The temporal expression of Si185/333-1 in peristomial membrane and coelomocytes were up-regulated after bacterial, ß-D-glucan and dsRNA challenges, reaching the maximum at 12 h post-stimulation. The up-regulation was more obvious in coelomocytes, and bacterial challenge triggered the highest response. These results proved that 185/333-1 gene was involved in the immune defense of S. intermedius, while more studies were necessary for its function in S. intermedius immunity.

  11. Lead poisoning

    MedlinePlus

    ... lead is still found in some modern faucets. Soil contaminated by decades of car exhaust or years ... house paint scrapings. Lead is more common in soil near highways and houses. Hobbies involving soldering, stained ...

  12. Improved energy coupling of human P-glycoprotein by the glycine 185 to valine mutation.

    PubMed

    Omote, Hiroshi; Figler, Robert A; Polar, Mark K; Al-Shawi, Marwan K

    2004-04-01

    A glycine 185 to valine mutation of human P-glycoprotein (ABCB1, MDR1) has been previously isolated from high colchicine resistance cell lines. We have employed purified and reconstituted P-glycoproteins expressed in Saccharomyces cerevisiae [Figler et al. (2000) Arch. Biochem. Biophys. 376, 34-46] and devised a set of thermodynamic analyses to reveal the mechanism of improved resistance. Purified G185V enzyme shows altered basal ATPase activity but a strong stimulation of colchicine- and etoposide-dependent activities, suggesting a tight regulation of ATPase activity by these drugs. The mutant enzyme has a higher apparent K(m) for colchicine and a lower K(m) for etoposide than that of wild type. Kinetic constants for other transported drugs were not significantly modified by this mutation. Systematic thermodynamic analyses indicate that the G185V enzyme has modified thermodynamic properties of colchicine- and etoposide-dependent activities. To improve the rate of colchicine or etoposide transport, the G185V enzyme has lowered the Arrhenius activation energy of the transport rate-limiting step. The high transition state energies of wild-type P-glycoprotein, when transporting etoposide or colchicine, increase the probability of nonproductive degradation of the transition state without transport. G185V P-glycoprotein transports etoposide or colchicine in an energetically more efficient way with decreased enthalpic and entropic components of the activation energy. Our new data fully reconcile the apparently conflicting results of previous studies. EPR analysis of the spin-labeled G185C enzyme in a cysteine-less background and kinetic parameters of the G185C enzyme indicate that position 185 is surrounded by other residues and is volume sensitive. These results and atomic detail structural modeling suggest that residue 185 is a pivotal point in transmitting conformational changes between the catalytic sites and the colchicine drug binding domain. Replacement of this

  13. Ultrastructural localization of highly variable 185/333 immune response proteins in the coelomocytes of the sea urchin, Heliocidaris erythrogramma.

    PubMed

    Dheilly, Nolwenn M; Birch, Debra; Nair, Sham V; Raftos, David A

    2011-11-01

    The 185/333 proteins of sea urchins represent a family of highly variable immune response molecules with unknown functions. In this study, we show that 185/333 proteins are expressed by three cell types: amoebocytes, colourless spherule cells and gut-associated amoebocytes. A sub-population of amoebocytes express 185/333 proteins on the membranes of vesicles emanating from the trans-Golgi and which later fuse with the plasma membranes of the cells. The previously uncharacterized gut-associated amoebocytes also show a high level of 185/333 protein expression on their internal vesicles and plasma membranes. Colourless spherule cells contain 185/333 proteins within large spherules (specialized intracellular vesicles). In the presence of bacteria and yeast, the ultrastucture of colourless spherule cells changes and 185/333 proteins disappear. In contrast, 185/333 proteins were not found in the phagosomes of coelomocytes. The 185/333-positive gut amoebocytes were often associated with anuclear bodies, which appeared to incorporate material of microbial origin that was surrounded by 185/333 proteins. The association between 185/333 proteins on gut amoebocytes and anuclear bodies suggests that these proteins may be involved in the phagocytosis of microbes in the gut epithelium. PMID:21577232

  14. Radioisotope yields from 1.85-GeV protons on Mo and 1.85- and 5.0-GeV protons on Te

    SciTech Connect

    Bardayan, D.W.; Hindi, M.M.; Barghouty, A.F.

    1995-05-01

    Radioisotope yields from 1.85-GeV proton interactions in a natural isotopic composition Mo target and those from 1.85- and 5.0-GeV protons in natural Te targets were measured at Lawrence Berkeley Laboratory`s Bevatron. The radioisotope yields were determined by {gamma}-counting the targets using a 100-cm{sup 3} coaxial Ge detector following the irradiations. Cross sections were determined for the production of 31 radioactive nuclides, ranging from Z = 35, A = 74, to Z = 43, A = 97, from the Mo target and for 47 radioactive nuclides, ranging from Z = 35, A = 75, to Z = 53, A = 130 from the Te targets.

  15. Detection of CO (J=1-0) in the dwarf elliptical galaxy NGC 185

    NASA Technical Reports Server (NTRS)

    Wiklind, Tommy; Rydbeck, Gustaf

    1987-01-01

    The detection of CO (J = 1-0) emission in the dwarf elliptical galaxy NGC 185 is reported. The presence of massive molecular clouds in this early-type galaxy supports the idea of recent or ongoing stellar formation indicated by the population of blue stars in the center. The CO was detected in two positions in the galaxy, the center, and a prominent dustcloud. The emission profile has two peaks, roughly centered around the systemic velocity. It is found that NGC 185 is overluminous in blue light for its CO luminosity compared with Sc galaxies. This might indicate a higher star-formation efficiency for NGC 185 than for the late-type galaxies.

  16. Lead Pencils

    NASA Technical Reports Server (NTRS)

    Gray, L. B.

    1971-01-01

    A study, undertaken to determine the lead content of paint on various pencils in the Goddard supply system, is reported. The survey found that lead content varied from .04 mg per pencil for carmine colored pencils to approximately 43 mg per pencil for yellow colored pencils. Results also show that yellow pencils had higher lead content than other colors analyzed. More detailed results are given in tabular form.

  17. Haplotype analysis of the 185delAG BRCA1 mutation in ethnically diverse populations

    PubMed Central

    Laitman, Yael; Feng, Bing-Jian; Zamir, Itay M; Weitzel, Jeffrey N; Duncan, Paul; Port, Danielle; Thirthagiri, Eswary; Teo, Soo-Hwang; Evans, Gareth; Latif, Ayse; Newman, William G; Gershoni-Baruch, Ruth; Zidan, Jamal; Shimon-Paluch, Shani; Goldgar, David; Friedman, Eitan

    2013-01-01

    The 185delAG* BRCA1 mutation is encountered primarily in Jewish Ashkenazi and Iraqi individuals, and sporadically in non-Jews. Previous studies estimated that this is a founder mutation in Jewish mutation carriers that arose before the dispersion of Jews in the Diaspora ∼2500 years ago. The aim of this study was to assess the haplotype in ethnically diverse 185delAG* BRCA1 mutation carriers, and to estimate the age at which the mutation arose. Ethnically diverse Jewish and non-Jewish 185delAG*BRCA1 mutation carriers and their relatives were genotyped using 15 microsatellite markers and three SNPs spanning 12.5 MB, encompassing the BRCA1 gene locus. Estimation of mutation age was based on a subset of 11 markers spanning a region of ∼5 MB, using a previously developed algorithm applying the maximum likelihood method. Overall, 188 participants (154 carriers and 34 noncarriers) from 115 families were included: Ashkenazi, Iraq, Kuchin-Indians, Syria, Turkey, Iran, Tunisia, Bulgaria, non-Jewish English, non-Jewish Malaysian, and Hispanics. Haplotype analysis indicated that the 185delAG mutation arose 750–1500 years ago. In Ashkenazim, it is a founder mutation that arose 61 generations ago, and with a small group of founder mutations was introduced into the Hispanic population (conversos) ∼650 years ago, and into the Iraqi–Jewish community ∼450 years ago. The 185delAG mutation in the non-Jewish populations in Malaysia and the UK arose at least twice independently. We conclude that the 185delAG* BRCA1 mutation resides on a common haplotype among Ashkenazi Jews, and arose about 61 generations ago and arose independently at least twice in non-Jews. PMID:22763381

  18. Haplotype analysis of the 185delAG BRCA1 mutation in ethnically diverse populations.

    PubMed

    Laitman, Yael; Feng, Bing-Jian; Zamir, Itay M; Weitzel, Jeffrey N; Duncan, Paul; Port, Danielle; Thirthagiri, Eswary; Teo, Soo-Hwang; Evans, Gareth; Latif, Ayse; Newman, William G; Gershoni-Baruch, Ruth; Zidan, Jamal; Shimon-Paluch, Shani; Goldgar, David; Friedman, Eitan

    2013-02-01

    The 185delAG* BRCA1 mutation is encountered primarily in Jewish Ashkenazi and Iraqi individuals, and sporadically in non-Jews. Previous studies estimated that this is a founder mutation in Jewish mutation carriers that arose before the dispersion of Jews in the Diaspora ~2500 years ago. The aim of this study was to assess the haplotype in ethnically diverse 185delAG* BRCA1 mutation carriers, and to estimate the age at which the mutation arose. Ethnically diverse Jewish and non-Jewish 185delAG*BRCA1 mutation carriers and their relatives were genotyped using 15 microsatellite markers and three SNPs spanning 12.5 MB, encompassing the BRCA1 gene locus. Estimation of mutation age was based on a subset of 11 markers spanning a region of ~5 MB, using a previously developed algorithm applying the maximum likelihood method. Overall, 188 participants (154 carriers and 34 noncarriers) from 115 families were included: Ashkenazi, Iraq, Kuchin-Indians, Syria, Turkey, Iran, Tunisia, Bulgaria, non-Jewish English, non-Jewish Malaysian, and Hispanics. Haplotype analysis indicated that the 185delAG mutation arose 750-1500 years ago. In Ashkenazim, it is a founder mutation that arose 61 generations ago, and with a small group of founder mutations was introduced into the Hispanic population (conversos) ~650 years ago, and into the Iraqi-Jewish community ~450 years ago. The 185delAG mutation in the non-Jewish populations in Malaysia and the UK arose at least twice independently. We conclude that the 185delAG* BRCA1 mutation resides on a common haplotype among Ashkenazi Jews, and arose about 61 generations ago and arose independently at least twice in non-Jews. PMID:22763381

  19. [Kinetic characteristics of glycosidases of Aspergillus niger 185III].

    PubMed

    Borzova, N V

    2005-01-01

    It was established, as a result of investigation of kinetic properties of two fungal glycosidases (alpha-N-acetylgalactosaminidase and alpha- galactosidase), that Km and Vmax for the corresponding synthetic substrates were 1.19 and 1.25 mM, 25.0 and 10.5 micromol/min/mg of protein, respectively. a-Galactosidase and alpha-N-acetylgalactosaminidase were also competitively inhibited by the reaction products - D-galactose and N-acetylgalactosamine, the inhibition constants were 8.5 x 10(-3) and 6.2 x 10(-2) M, respectively. One could also observe the inhibition of alpha-galactosidase reaction in the presence of 10(-3) M of fucose, lactose and arabinose. It was shown that the rate of enzymatic hydrolysis of nitrophenyl substrates was directly proportional to the concentration of enzymes, and the increase of the substrate concentration leads to the increase of hydrolysis rate. The substrate concentration being increased above the optimal one (3.6 mg/ml), the decrease of the reaction rate owing to the formation of inactive enzyme-substrate complex FS2 may be observed. PMID:16018204

  20. Leading Democratically

    ERIC Educational Resources Information Center

    Brookfield, Stephen

    2010-01-01

    Democracy is the most venerated of American ideas, the one for which wars are fought and people die. So most people would probably agree that leaders should be able to lead well in a democratic society. Yet, genuinely democratic leadership is a relative rarity. Leading democratically means viewing leadership as a function or process, rather than…

  1. 14 CFR 135.185 - Empty weight and center of gravity: Currency requirement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Empty weight and center of gravity... ON BOARD SUCH AIRCRAFT Aircraft and Equipment § 135.185 Empty weight and center of gravity: Currency... gravity are calculated from values established by actual weighing of the aircraft within the preceding...

  2. 14 CFR 135.185 - Empty weight and center of gravity: Currency requirement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Empty weight and center of gravity... ON BOARD SUCH AIRCRAFT Aircraft and Equipment § 135.185 Empty weight and center of gravity: Currency... gravity are calculated from values established by actual weighing of the aircraft within the preceding...

  3. 14 CFR 135.185 - Empty weight and center of gravity: Currency requirement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Empty weight and center of gravity... ON BOARD SUCH AIRCRAFT Aircraft and Equipment § 135.185 Empty weight and center of gravity: Currency... gravity are calculated from values established by actual weighing of the aircraft within the preceding...

  4. 14 CFR 135.185 - Empty weight and center of gravity: Currency requirement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Empty weight and center of gravity... ON BOARD SUCH AIRCRAFT Aircraft and Equipment § 135.185 Empty weight and center of gravity: Currency... gravity are calculated from values established by actual weighing of the aircraft within the preceding...

  5. 5 CFR 185.117 - Disqualification of reviewing official or ALJ.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Disqualification of reviewing official or... REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.117 Disqualification of reviewing official or ALJ. (a) A reviewing official or ALJ in a particular case may disqualify himself or herself at any time. (b) A...

  6. Draft Genome Sequence of Probiotic Strain Pediococcus acidilactici MA18/5M

    PubMed Central

    Barreau, Guillaume; de Carvalho, Vanessa G.

    2012-01-01

    Pediococcus acidilactici MA18/5M is a commercially available probiotic that is widely used in swine, poultry, aquaculture feeds, and human dietary supplements. We prepared a genome sequence for this strain consisting of 2 scaffolds totaling 1,992,928 bases including gaps for a total of 3,346 bases and a G+C content of 42%. PMID:22275099

  7. 42 CFR 440.185 - Respiratory care for ventilator-dependent individuals.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... care professional trained in respiratory therapy (as determined by the State) to an individual who— (1... 42 Public Health 4 2010-10-01 2010-10-01 false Respiratory care for ventilator-dependent... Definitions § 440.185 Respiratory care for ventilator-dependent individuals. (a) “Respiratory care...

  8. 42 CFR 440.185 - Respiratory care for ventilator-dependent individuals.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... health care professional trained in respiratory therapy (as determined by the State) to an individual who... 42 Public Health 4 2012-10-01 2012-10-01 false Respiratory care for ventilator-dependent... Definitions § 440.185 Respiratory care for ventilator-dependent individuals. (a) “Respiratory care...

  9. 42 CFR 440.185 - Respiratory care for ventilator-dependent individuals.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... health care professional trained in respiratory therapy (as determined by the State) to an individual who... 42 Public Health 4 2013-10-01 2013-10-01 false Respiratory care for ventilator-dependent... Definitions § 440.185 Respiratory care for ventilator-dependent individuals. (a) “Respiratory care...

  10. 42 CFR 440.185 - Respiratory care for ventilator-dependent individuals.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... health care professional trained in respiratory therapy (as determined by the State) to an individual who... 42 Public Health 4 2014-10-01 2014-10-01 false Respiratory care for ventilator-dependent... Definitions § 440.185 Respiratory care for ventilator-dependent individuals. (a) “Respiratory care...

  11. 41 CFR 102-3.185 - What does this subpart require agencies to do?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... National Academy of Sciences or the National Academy of Public Administration? § 102-3.185 What does this... recommendation provided to an agency by the National Academy of Sciences (NAS) or the National Academy of Public Administration (NAPA) under an agreement between the agency and an academy, if such advice or recommendation......

  12. 41 CFR 102-3.185 - What does this subpart require agencies to do?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... National Academy of Sciences or the National Academy of Public Administration? § 102-3.185 What does this... recommendation provided to an agency by the National Academy of Sciences (NAS) or the National Academy of Public Administration (NAPA) under an agreement between the agency and an academy, if such advice or recommendation......

  13. 14 CFR 91.185 - IFR operations: Two-way radio communications failure.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false IFR operations: Two-way radio... RULES Flight Rules Instrument Flight Rules § 91.185 IFR operations: Two-way radio communications failure. (a) General. Unless otherwise authorized by ATC, each pilot who has two-way radio...

  14. 33 CFR 110.185 - Atlantic Ocean, off the Port of Palm Beach, FL.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Atlantic Ocean, off the Port of... HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.185 Atlantic Ocean, off the Port... regulations. (1) Vessels in the Atlantic Ocean near Lake Worth Inlet awaiting berthing space at the Port...

  15. 33 CFR 110.185 - Atlantic Ocean, off the Port of Palm Beach, FL.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Atlantic Ocean, off the Port of... HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.185 Atlantic Ocean, off the Port... regulations. (1) Vessels in the Atlantic Ocean near Lake Worth Inlet awaiting berthing space at the Port...

  16. 33 CFR 110.185 - Atlantic Ocean, off the Port of Palm Beach, FL.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Atlantic Ocean, off the Port of... HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.185 Atlantic Ocean, off the Port... regulations. (1) Vessels in the Atlantic Ocean near Lake Worth Inlet awaiting berthing space at the Port...

  17. 33 CFR 110.185 - Atlantic Ocean, off the Port of Palm Beach, FL.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Atlantic Ocean, off the Port of... HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.185 Atlantic Ocean, off the Port... regulations. (1) Vessels in the Atlantic Ocean near Lake Worth Inlet awaiting berthing space at the Port...

  18. 33 CFR 110.185 - Atlantic Ocean, off the Port of Palm Beach, FL.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Atlantic Ocean, off the Port of... HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.185 Atlantic Ocean, off the Port... regulations. (1) Vessels in the Atlantic Ocean near Lake Worth Inlet awaiting berthing space at the Port...

  19. 31 CFR 103.185 - Summons or subpoena of foreign bank records; Termination of correspondent relationship.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... TRANSACTIONS Anti-Money Laundering Programs Law Enforcement Access to Foreign Bank Records § 103.185 Summons or... than 7 days after receipt of the request. (d) Termination upon receipt of notice. A covered financial... in accordance with paragraph (d) of this section. (f) Failure to terminate relationship. Failure...

  20. 14 CFR 121.185 - Airplanes: Reciprocating engine-powered: Landing limitations: Destination airport.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Airplanes: Reciprocating engine-powered...: CERTIFICATION AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Airplane Performance Operating Limitations § 121.185 Airplanes: Reciprocating engine-powered: Landing...

  1. 14 CFR 121.185 - Airplanes: Reciprocating engine-powered: Landing limitations: Destination airport.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Airplanes: Reciprocating engine-powered...: CERTIFICATION AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Airplane Performance Operating Limitations § 121.185 Airplanes: Reciprocating engine-powered: Landing...

  2. 14 CFR 121.185 - Airplanes: Reciprocating engine-powered: Landing limitations: Destination airport.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Airplanes: Reciprocating engine-powered...: CERTIFICATION AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Airplane Performance Operating Limitations § 121.185 Airplanes: Reciprocating engine-powered: Landing...

  3. 46 CFR 185.212 - Mandatory chemical testing following serious marine incidents.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Mandatory chemical testing following serious marine... PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Marine Casualties and Voyage Records § 185.212 Mandatory chemical testing following serious marine incidents. A marine employer whose vessel is involved in...

  4. 46 CFR 185.212 - Mandatory chemical testing following serious marine incidents.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Mandatory chemical testing following serious marine... PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Marine Casualties and Voyage Records § 185.212 Mandatory chemical testing following serious marine incidents. A marine employer whose vessel is involved in...

  5. 14 CFR 91.185 - IFR operations: Two-way radio communications failure.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 2 2013-01-01 2013-01-01 false IFR operations: Two-way radio... RULES Flight Rules Instrument Flight Rules § 91.185 IFR operations: Two-way radio communications failure. (a) General. Unless otherwise authorized by ATC, each pilot who has two-way radio...

  6. 14 CFR 91.185 - IFR operations: Two-way radio communications failure.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 2 2011-01-01 2011-01-01 false IFR operations: Two-way radio... RULES Flight Rules Instrument Flight Rules § 91.185 IFR operations: Two-way radio communications failure. (a) General. Unless otherwise authorized by ATC, each pilot who has two-way radio...

  7. 14 CFR 91.185 - IFR operations: Two-way radio communications failure.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 2 2012-01-01 2012-01-01 false IFR operations: Two-way radio... RULES Flight Rules Instrument Flight Rules § 91.185 IFR operations: Two-way radio communications failure. (a) General. Unless otherwise authorized by ATC, each pilot who has two-way radio...

  8. 14 CFR 91.185 - IFR operations: Two-way radio communications failure.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 2 2014-01-01 2014-01-01 false IFR operations: Two-way radio... RULES Flight Rules Instrument Flight Rules § 91.185 IFR operations: Two-way radio communications failure. (a) General. Unless otherwise authorized by ATC, each pilot who has two-way radio...

  9. 14 CFR 121.185 - Airplanes: Reciprocating engine-powered: Landing limitations: Destination airport.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Airplanes: Reciprocating engine-powered...: CERTIFICATION AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Airplane Performance Operating Limitations § 121.185 Airplanes: Reciprocating engine-powered: Landing...

  10. 14 CFR 135.185 - Empty weight and center of gravity: Currency requirement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Empty weight and center of gravity... ON BOARD SUCH AIRCRAFT Aircraft and Equipment § 135.185 Empty weight and center of gravity: Currency... gravity are calculated from values established by actual weighing of the aircraft within the preceding...

  11. Characterization of the Highly Variable Immune Response Gene Family, He185/333, in the Sea Urchin, Heliocidaris erythrogramma

    PubMed Central

    Roth, Mattias O.; Wilkins, Adam G.; Cooke, Georgina M.; Raftos, David A.; Nair, Sham V.

    2014-01-01

    This study characterizes the highly variable He185/333 genes, transcripts and proteins in coelomocytes of the sea urchin, Heliocidaris erythrogramma. Originally discovered in the purple sea urchin, Strongylocentrotus purpuratus, the products of this gene family participate in the anti-pathogen defenses of the host animals. Full-length He185/333 genes and transcripts are identified. Complete open reading frames of He185/333 homologues are analyzed as to their element structure, single nucleotide polymorphisms, indels and sequence repeats and are subjected to diversification analyses. The sequence elements that compose He185/333 are different to those identified for Sp185/333. Differences between Sp185/333 and He185/333 genes are also evident in the complexity of the sequences of the introns. He185/333 proteins show a diverse range of molecular weights on Western blots. The observed sizes and pIs of the proteins differ from predicted values, suggesting post-translational modifications and oligomerization. Immunofluorescence microscopy shows that He185/333 proteins are mainly located on the surface of coelomocyte subpopulations. Our data demonstrate that He185/333 bears the same substantial characteristics as their S. purpuratus homologues. However, we also identify several unique characteristics of He185/333 (such as novel element patterns, sequence repeats, distribution of positively-selected codons and introns), suggesting species-specific adaptations. All sequences in this publication have been submitted to Genbank (accession numbers JQ780171-JQ780321) and are listed in table S1. PMID:25333281

  12. A PAndAS view of M31 dwarf elliptical satellites: NGC 147 and NGC 185

    NASA Astrophysics Data System (ADS)

    Crnojević, D.; Ferguson, A. M. N.; Irwin, M. J.; McConnachie, A. W.; Bernard, E. J.; Fardal, M. A.; Ibata, R. A.; Lewis, G. F.; Martin, N. F.; Navarro, J. F.; Noël, N. E. D.; Pasetto, S.

    2014-12-01

    We exploit data from the Pan-Andromeda Archaeological Survey (PAndAS) to study the extended structures of M31's dwarf elliptical companions, NGC 147 and NGC 185. Our wide-field, homogeneous photometry allows us to construct deep colour-magnitude diagrams which reach down to ˜3 mag below the red giant branch (RGB) tip. We trace the stellar components of the galaxies to surface brightness of μg ˜ 32 mag arcsec-2 and show that they have much larger extents (˜5 kpc radii) than previously recognized. While NGC 185 retains a regular shape in its peripheral regions, NGC 147 exhibits pronounced isophotal twisting due to the emergence of symmetric tidal tails. We fit single Sérsic models to composite surface brightness profiles constructed from diffuse light and star counts and find that NGC 147 has an effective radius almost three times that of NGC 185. In both cases, the effective radii that we calculate are larger by a factor of ˜2 compared to most literature values. We also calculate revised total magnitudes of Mg = -15.36 ± 0.04 for NGC 185 and Mg = -16.36 ± 0.04 for NGC 147. Using photometric metallicities computed for RGB stars, we find NGC 185 to exhibit a metallicity gradient of [Fe/H] ˜ -0.15 dex kpc-1 over the radial range 0.125-0.5 deg. On the other hand, NGC 147 exhibits almost no metallicity gradient, ˜-0.02 dex kpc-1 from 0.2 to 0.6 deg. The differences in the structure and stellar populations in the outskirts of these systems suggest that tidal influences have played an important role in governing the evolution of NGC 147.

  13. 34 CFR 403.185 - How does the Secretary compute maintenance of effort in the event of a waiver?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... VOCATIONAL AND APPLIED TECHNOLOGY EDUCATION PROGRAM What Financial Conditions Must Be Met by a State? § 403... 34 Education 3 2013-07-01 2013-07-01 false How does the Secretary compute maintenance of effort in the event of a waiver? 403.185 Section 403.185 Education Regulations of the Offices of the...

  14. 34 CFR 403.185 - How does the Secretary compute maintenance of effort in the event of a waiver?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... VOCATIONAL AND APPLIED TECHNOLOGY EDUCATION PROGRAM What Financial Conditions Must Be Met by a State? § 403... 34 Education 3 2014-07-01 2014-07-01 false How does the Secretary compute maintenance of effort in the event of a waiver? 403.185 Section 403.185 Education Regulations of the Offices of the...

  15. 41 CFR 102-73.185 - What types of special purpose space may the Department of Energy lease?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What types of special purpose space may the Department of Energy lease? 102-73.185 Section 102-73.185 Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION REAL PROPERTY 73-REAL ESTATE...

  16. 41 CFR 102-73.185 - What types of special purpose space may the Department of Energy lease?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false What types of special purpose space may the Department of Energy lease? 102-73.185 Section 102-73.185 Public Contracts and... REGULATION REAL PROPERTY 73-REAL ESTATE ACQUISITION Acquisition by Lease Special Purpose Space...

  17. 34 CFR 668.185 - Draft cohort default rates and your ability to challenge before official cohort default rates are...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... challenge before official cohort default rates are issued. 668.185 Section 668.185 Education Regulations of... cohort default rates and your ability to challenge before official cohort default rates are issued. (a... may not be otherwise voluntarily released to the public by a data manager. (4) Any challenge...

  18. 34 CFR 668.185 - Draft cohort default rates and your ability to challenge before official cohort default rates are...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... challenge before official cohort default rates are issued. 668.185 Section 668.185 Education Regulations of... cohort default rates and your ability to challenge before official cohort default rates are issued. (a... may not be otherwise voluntarily released to the public by a data manager. (4) Any challenge...

  19. 34 CFR 668.185 - Draft cohort default rates and your ability to challenge before official cohort default rates are...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... challenge before official cohort default rates are issued. 668.185 Section 668.185 Education Regulations of... cohort default rates and your ability to challenge before official cohort default rates are issued. (a... may not be otherwise voluntarily released to the public by a data manager. (4) Any challenge...

  20. 34 CFR 668.185 - Draft cohort default rates and your ability to challenge before official cohort default rates are...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... challenge before official cohort default rates are issued. 668.185 Section 668.185 Education Regulations of... cohort default rates and your ability to challenge before official cohort default rates are issued. (a... may not be otherwise voluntarily released to the public by a data manager. (4) Any challenge...

  1. 34 CFR 668.185 - Draft cohort default rates and your ability to challenge before official cohort default rates are...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... challenge before official cohort default rates are issued. 668.185 Section 668.185 Education Regulations of... cohort default rates and your ability to challenge before official cohort default rates are issued. (a... may not be otherwise voluntarily released to the public by a data manager. (4) Any challenge...

  2. miR-185-3p regulates nasopharyngeal carcinoma radioresistance by targeting WNT2B in vitro

    PubMed Central

    Li, Guo; Wang, Yunyun; Liu, Yong; Su, Zhongwu; Liu, Chao; Ren, Shuling; Deng, Tengbo; Huang, Donghai; Tian, Yongquan; Qiu, Yuanzheng

    2014-01-01

    Aberrant microRNA (miRNA) expression contributes to a series of malignant cancer behaviors, including radioresistance. Our previous study showed differential expression of miR-185-3p in post-radiation nasopharyngeal carcinoma (NPC) cells. To investigate the role of miR-185-3p in NPC radioresistance, CNE-2 and 5-8F cells were transfected with miR-185-3p mimic and miR-185-3p inhibitor, respectively. CCK-8 assay and colony formation experiment confirmed that the expression of miR-185-3p affected the radioresistance of NPC cells. A negative correlation between miR-185-3p and WNT2B expression was observed in NPC cells and tissues. Luciferase reporter assays confirmed that miR-185-3p directly targeted the coding region of WNT2B. Furthermore, we found radioresistance decreased in WNT2B-silenced NPC cells. Activation of the WNT2B/β-catenin pathway was accompanied by epithelial–mesenchymal transition biomarker changes in NPC. We concluded that miR-185-3p contributed to the radioresistance of NPC via modulation of WNT2B expression in vitro. PMID:25297925

  3. 75 FR 69861 - Airworthiness Directives; Cessna Aircraft Company (Cessna) 172, 175, 177, 180, 182, 185, 206, 207...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-16

    ....johnson@faa.gov . SUPPLEMENTARY INFORMATION: Airworthiness Directive 2008-26-10, Amendment 39-15776 (73 FR... Company (Cessna) 172, 175, 177, 180, 182, 185, 206, 207, 208, 210, 303, 336, and 337 Series Airplanes... obstruction is found for certain Cessna 172, 175, 177, 180, 182, 185, 206, 207, 208, 210, 303, 336, and...

  4. Ecotoxicology: Lead

    USGS Publications Warehouse

    Scheuhammer, A.M.; Beyer, W.N.; Schmitt, C.J.

    2008-01-01

    Lead (Pb) is a naturally occurring metallic element; trace concentrations are found in all environmental media and in all living things. However, certain human activities, especially base metal mining and smelting; combustion of leaded gasoline; the use of Pb in hunting, target shooting, and recreational angling; the use of Pb-based paints; and the uncontrolled disposal of Pb-containing products such as old vehicle batteries and electronic devices have resulted in increased environmental levels of Pb, and have created risks for Pb exposure and toxicity in invertebrates, fish, and wildlife in some ecosystems.

  5. Tetraethyl lead

    Integrated Risk Information System (IRIS)

    Tetraethyl lead ; CASRN 78 - 00 - 2 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Noncarcinogenic Ef

  6. Innate immune complexity in the purple sea urchin: diversity of the sp185/333 system.

    PubMed

    Smith, L Courtney

    2012-01-01

    The California purple sea urchin, Strongylocentrotus purpuratus, is a long-lived echinoderm with a complex and sophisticated innate immune system. There are several large gene families that function in immunity in this species including the Sp185/333 gene family that has ∼50 (±10) members. The family shows intriguing sequence diversity and encodes a broad array of diverse yet similar proteins. The genes have two exons of which the second encodes the mature protein and has repeats and blocks of sequence called elements. Mosaics of element patterns plus single nucleotide polymorphisms-based variants of the elements result in significant sequence diversity among the genes yet maintains similar structure among the members of the family. Sequence of a bacterial artificial chromosome insert shows a cluster of six, tightly linked Sp185/333 genes that are flanked by GA microsatellites. The sequences between the GA microsatellites in which the Sp185/333 genes and flanking regions are located, are much more similar to each other than are the sequences outside the microsatellites suggesting processes such as gene conversion, recombination, or duplication. However, close linkage does not correspond with greater sequence similarity compared to randomly cloned and sequenced genes that are unlikely to be linked. There are three segmental duplications that are bounded by GAT microsatellites and include three almost identical genes plus flanking regions. RNA editing is detectible throughout the mRNAs based on comparisons to the genes, which, in combination with putative post-translational modifications to the proteins, results in broad arrays of Sp185/333 proteins that differ among individuals. The mature proteins have an N-terminal glycine-rich region, a central RGD motif, and a C-terminal histidine-rich region. The Sp185/333 proteins are localized to the cell surface and are found within vesicles in subsets of polygonal and small phagocytes. The coelomocyte proteome shows full

  7. Extraterrestrial demise of banded iron formations 1.85 billion years ago

    USGS Publications Warehouse

    Slack, J.F.; Cannon, W.F.

    2009-01-01

    In the Lake Superior region of North America, deposition of most banded iron formations (BIFs) ended abruptly 1.85 Ga ago, coincident with the oceanic impact of the giant Sudbury extraterrestrial bolide. We propose a new model in which this impact produced global mixing of shallow oxic and deep anoxic waters of the Paleoproterozoic ocean, creating a suboxic redox state for deep seawater. This suboxic state, characterized by only small concentrations of dissolved O2 (???1 ??M), prevented transport of hydrothermally derived Fe(II) from the deep ocean to continental-margin settings, ending an ???1.1 billion-year-long period of episodic BIF mineralization. The model is supported by the nature of Precambrian deep-water exhalative chemical sediments, which changed from predominantly sulfide facies prior to ca. 1.85 Ga to mainly oxide facies thereafter. ?? 2009 Geological Society of America.

  8. Biochemical changes in rat liver after 18.5 days of spaceflight (41566)

    NASA Technical Reports Server (NTRS)

    Abraham, S.; Lin, C.Y.; Volkmann, C. M.; Klein, H. P.

    1983-01-01

    The effect of weightlessness on liver metabolism was investigated using tissue from rats flown in earth orbit for 18.5 days on the Soviet Cosmos 936 biosatellite and the changes in the activities of 28 carbohydrate and lipid enzymes were determined. The activities of two enzymes, palmitoyl-CoA desaturase and lactate dehydrogenase, increased, while the activities of five, glycogen phosphorylase, 6-phosphogluconate dehydrogenase, both acyltransferases which act on alpha-glycerolphosphate and diglycerides, and and aconitate hydratase decreased. The other enzyme activities were found to be unchanged. In addition, increased levels of liver glycogen and palmitoleate were detected which probably resulted from the lowered glycogen phosphorylase and increased palmitoyl-CoA desaturase activities, respectively, in those animals that experienced weightlessness. All of the changes observed in the rats after 18.5 days of spaceflight disappear by 25 days after the flight.

  9. Physical nature of the [S II]-bright shell nebulae N70 and N185

    SciTech Connect

    Zhang, Ning-Xiao; Jiang, Bing; Chen, Yang; Chu, You-Hua; Gruendl, R. A.; Williams, R. M.

    2014-09-01

    N70 and N185 are two large (≥100 pc in diameter) shell nebulae in the Large Magellanic Cloud (LMC). Their high [S II]/Hα ratios rival those of supernova remnants (SNRs), but they are not confirmed as SNRs. To study their physical nature, we have obtained XMM-Newton X-ray observations and high-dispersion long-slit echelle spectroscopic observations of these two nebulae. The X-ray spectra of both nebulae can be well interpreted with an optically thin thermal (∼0.2 keV) plasma with the average LMC abundance in a collisional ionization equilibrium. N70 encompasses the OB association LH114. Although N70 has a modest expansion velocity and essentially thermal radio emission, its diffuse X-ray luminosity (∼6.1 × 10{sup 35} erg s{sup –1}) is higher than that from a quiescent superbubble with N70's density, size, and expansion velocity; thus, N70 is most likely a superbubble that is recently energized by an interior SNR. N185 does not contain any known OB association, and its X-ray luminosity is an order of magnitude lower than expected if it is a quiescent superbubble. N185 has nonthermal radio emission and has high-velocity material expanding at nearly 200 km s{sup –1}, similar to many known SNRs in the LMC. Its X-ray luminosity (∼1.9 × 10{sup 35} erg s{sup –1}) is also consistent with that of an evolved SNR. We therefore suggest that N185 is energized by a recent supernova.

  10. Investigation of 186Re via radiative thermal-neutron capture on 185Re

    NASA Astrophysics Data System (ADS)

    Matters, D. A.; Lerch, A. G.; Hurst, A. M.; Szentmiklósi, L.; Carroll, J. J.; Detwiler, B.; Révay, Zs.; McClory, J. W.; McHale, S. R.; Firestone, R. B.; Sleaford, B. W.; Krtička, M.; Belgya, T.

    2016-05-01

    Partial γ -ray production cross sections and the total radiative thermal-neutron capture cross section for the 185Re(n ,γ ) 186Re reaction were measured using the Prompt Gamma Activation Analysis facility at the Budapest Research Reactor with an enriched 185Re target. The 186Re cross sections were standardized using well-known 35Cl(n ,γ )36Cl cross sections from irradiation of a stoichiometric natReCl3 target. The resulting cross sections for transitions feeding the 186Re ground state from low-lying levels below a cutoff energy of Ec=746 keV were combined with a modeled probability of ground-state feeding from levels above Ec to arrive at a total cross section of σ0=111 (6 ) b for radiative thermal-neutron capture on 185Re. A comparison of modeled discrete-level populations with measured transition intensities led to proposed revisions for seven tentative spin-parity assignments in the adopted level scheme for 186Re. Additionally, 102 primary γ rays were measured, including 50 previously unknown. A neutron-separation energy of Sn=6179.59 (5 ) keV was determined from a global least-squares fit of the measured γ -ray energies to the known 186Re decay scheme. The total capture cross section and separation energy results are comparable to earlier measurements of these values.

  11. AHNP-Streptavidin: A Tetrameric Bacterially Produced Antibody Surrogate Fusion Protein Against p185her2/neu

    SciTech Connect

    Masuda,K.; Richter, M.; Song, X.; Berezov, A.; Masuda, K.; Murali, R.; Greene, M.; Zhang, H.

    2006-01-01

    The anti-p185her2/neu peptidomimetic (AHNP) is a small exo-cyclic peptide derived from the anti-p185her2/neu rhumAb 4D5 (h4D5). AHNP mimics many but not all of the antitumor characteristics exhibited by h4D5. However, the pharmacokinetic profiles of AHNP are less than optimal for therapeutic or diagnostic purposes. To improve the binding affinity to p185her2/neu and the antitumor efficacy, we have engineered a fusion protein containing AHNP and a nonimmunoglobulin protein scaffold, streptavidin (SA). The recombinant protein, AHNP-SA (ASA) bound to p185her2/neu with high affinity, inhibited the proliferation of p185her2/neu-overexpressing cells, and reduced tumor growth induced by p185her2/neu-transformed cells. These data suggest that the bacterially produced tetrameric ASA can be used as an antibody-surrogate molecule. This class of molecule will play a role in the diagnosis and treatment of p185her2/neu-related tumors. Our studies establish a general principle by which a small biologically active synthetic exo-cyclic peptide can be engineered to enhance functional aspects by structured oligomerization and can be produced recombinantly using bacterial expression.

  12. Identification of miR-185 as a regulator of de novo cholesterol biosynthesis and low density lipoprotein uptake.

    PubMed

    Yang, Muhua; Liu, Weidong; Pellicane, Christina; Sahyoun, Christine; Joseph, Biny K; Gallo-Ebert, Christina; Donigan, Melissa; Pandya, Devanshi; Giordano, Caroline; Bata, Adam; Nickels, Joseph T

    2014-02-01

    Dysregulation of cholesterol homeostasis is associated with various metabolic diseases, including atherosclerosis and type 2 diabetes. The sterol response element binding protein (SREBP)-2 transcription factor induces the expression of genes involved in de novo cholesterol biosynthesis and low density lipoprotein (LDL) uptake, thus it plays a crucial role in maintaining cholesterol homeostasis. Here, we found that overexpressing microRNA (miR)-185 in HepG2 cells repressed SREBP-2 expression and protein level. miR-185-directed inhibition caused decreased SREBP-2-dependent gene expression, LDL uptake, and HMG-CoA reductase activity. In addition, we found that miR-185 expression was tightly regulated by SREBP-1c, through its binding to a single sterol response element in the miR-185 promoter. Moreover, we found that miR-185 expression levels were elevated in mice fed a high-fat diet, and this increase correlated with an increase in total cholesterol level and a decrease in SREBP-2 expression and protein. Finally, we found that individuals with high cholesterol had a 5-fold increase in serum miR-185 expression compared with control individuals. Thus, miR-185 controls cholesterol homeostasis through regulating SREBP-2 expression and activity. In turn, SREBP-1c regulates miR-185 expression through a complex cholesterol-responsive feedback loop. Thus, a novel axis regulating cholesterol homeostasis exists that exploits miR-185-dependent regulation of SREBP-2 and requires SREBP-1c for function. PMID:24296663

  13. Measurements of absolute absorption cross sections of ozone in the 185- to 254-nm wavelength region and the temperature dependence

    NASA Technical Reports Server (NTRS)

    Yoshino, K.; Esmond, J. R.; Freeman, D. E.; Parkinson, W. H.

    1993-01-01

    Laboratory measurements of the relative absorption cross sections of ozone at temperatures 195, 228, and 295 K have been made throughout the 185 to 254 nm wavelength region. The absolute absorption cross sections at the same temperatures have been measured at several discrete wavelengths in the 185 to 250 nm region. The absolute cross sections of ozone have been used to put the relative cross sections on a firm absolute basis throughout the 185 to 255 nm region. These recalibrated cross sections are slightly lower than those of Molina and Molina (1986), but the differences are within a few percent and would not be significant in atmospheric applications.

  14. Shape-changing particle decays of 185 Bi and structure of the lightest odd-mass Bi isotopes

    NASA Astrophysics Data System (ADS)

    Andreyev, A. N.; Ackermann, D.; Heßberger, F. P.; Heyde, K.; Hofmann, S.; Huyse, M.; Karlgren, D.; Kojouharov, I.; Kindler, B.; Lommel, B.; Münzenberg, G.; Page, R. D.; van de Vel, K.; van Duppen, P.; Walters, W. B.; Wyss, R.

    2004-05-01

    Proton and α decay of the proton-rich nuclide 185 Bi has been restudied in more detail in the complete fusion reaction 93 Nb ( 95 Mo ,3n ) 185 Bi at the velocity filter SHIP. The observed decay pattern of 185 Bi and of the heavier odd-mass isotopes 187,189,191,193 Bi are interpreted based on potential-energy surface calculations. It is shown that the experimental systematics of the particle decays and of the excited states in these nuclei (where known) can be explained by the prolate-oblate shape co-existence at low excitation energy. The observed state in 185 Bi is proposed to be of prolate nature, which is in contrast with the previously proposed oblate interpretation.

  15. Effect of granularity and annealing conditions on the magneto-resistance of the electron doped superconductor Nd1.85Ce0.15CuO4

    NASA Astrophysics Data System (ADS)

    Raveendran, N. Radhikesh; Amaladass, E. P.; Janaki, J.; Mani, Awadhesh

    2016-05-01

    A single phase polycrystalline sample of Nd1.85Ce0.15CuO4 has been synthesized and well characterized. Detailed studies on electrical resistivity behavior of this system as a function of temperature and magnetic field reveal interesting features attributable to the granularity effects. These features have been qualitatively understood based on the interplay of Josephson junction coupling and quasi particle tunneling which dictates the evolution of the observed temperature and field dependent resistivity behavior of Nd1.85Ce0.15CuO4 system. The studies also reveal significant changes with respect to annealing conditions, indicating that such compounds are very sensitive to annealing conditions. It has been observed that prolonged annealing in Argon atmosphere leads to a decrease in normal state resistivity. This is associated with a decrease in the S-I-S type Josephson tunnel junctions perhaps due to improved inter-granular coupling, nevertheless they could not be completely eliminated.

  16. Cul7/p185/p193 binding to simian virus 40 large T antigen has a role in cellular transformation.

    PubMed

    Ali, Syed Hamid; Kasper, Jocelyn S; Arai, Takehiro; DeCaprio, James A

    2004-03-01

    Simian virus 40 large T antigen (TAg) is a viral oncoprotein that can promote cellular transformation. TAg's transforming activity results in part by binding and inactivating key tumor suppressors, including p53 and the retinoblastoma protein (pRb). We have identified a TAg-associated 185-kDa protein that has significant homology to the cullin family of E3 ubiquitin ligases. TAg binds to an SCF-like complex that contains p185/Cul7, Rbx1, and the F box protein Fbw6. This SCF-like complex binds to an N-terminal region of TAg. Several p185/Cul7-binding-deficient mutants of TAg were generated that retained binding to pRb and p53 and were capable of overcoming Rb-mediated repression of E2F transcription. Despite binding to pRb and p53, these p185/Cul7-binding-defective mutants of TAg were unable to transform primary mouse embryo fibroblasts. Cells expressing p185/Cul7-binding-defective mutants of TAg were unable to grow to high density or grow in an anchorage-independent manner as determined by growth in soft agar. Considering the significance of other TAg-interacting proteins in regulation of the cell cycle, p185/Cul7 may also regulate an important growth control pathway. PMID:14990695

  17. Computer modeling of the neurotoxin binding site of acetylcholine receptor spanning residues 185 through 196

    NASA Technical Reports Server (NTRS)

    Garduno-Juarez, R.; Shibata, M.; Zielinski, T. J.; Rein, R.

    1987-01-01

    A model of the complex between the acetylcholine receptor and the snake neurotoxin, cobratoxin, was built by molecular model building and energy optimization techniques. The experimentally identified functionally important residues of cobratoxin and the dodecapeptide corresponding to the residues 185-196 of acetylcholine receptor alpha subunit were used to build the model. Both cis and trans conformers of cyclic L-cystine portion of the dodecapeptide were examined. Binding residues independently identified on cobratoxin are shown to interact with the dodecapeptide AChR model.

  18. Absolute absorption cross sections of ozone in the 185- to 350-nm wavelength range

    NASA Technical Reports Server (NTRS)

    Molina, L. T.; Molina, M. J.

    1986-01-01

    The absorption cross sections of ozone have been measured in the wavelength range 185-350 nm and in the temperature range 225-298 K. The absolute ozone concentrations were established by measuring the pressure of pure gaseous samples in the 0.08to 300-torr range, and the UV spectra were recorded under conditions where less than 1 percent of the sample decomposed. The temperature dependence is significant for wavelengths longer than about 280 nm. The absorption cross-section values around 210 nm were found to be about 10 percent larger than the previously accepted values.

  19. Optimizing Radiolabeled Engineered Anti-p185HER2 Antibody Fragments for In vivo Imaging

    PubMed Central

    Olafsen, Tove; Kenanova, Vania E.; Sundaresan, Gobalakrishnan; Anderson, Anne-Line; Crow, Desiree; Yazaki, Paul J.; Li, Lin; Press, Michael F.; Gambhir, Sanjiv S.; Williams, Lawrence E.; Wong, Jeffrey Y.C.; Raubitschek, Andrew A.; Shively, John E.; Wu, Anna M.

    2014-01-01

    We have recently described the in vivo properties of an iodinated anti-p185HER2 engineered antibody fragment [minibody (scFv-CH3)2; 80 kDa], made from the internalizing 10H8 monoclonal antibody. Although the 10H8 minibody showed excellent binding to the target in vitro, only modest tumor uptake [5.6 ± 1.7% injected dose per gram (ID/g) of tissue] was achieved in nude mice bearing MCF7/HER2 breast cancer tumors. Here, in an attempt to improve targeting, the 10H8 minibody was conjugated to 1,4,7,10-tetraazacyclododecane-N, N′, N″, N‴-tetraacetic acid (DOTA), radio metal labeled, and evaluated in vivo. The tumor uptake of 111In-DOTA 10H8 minibody was 5.7 ± 0.1% ID/g, similar to the radioiodinated 10H8 minibody. However, in addition to the expected liver clearance, the kidneys had unexpectedly high activity (34.0 ± 4.0% ID/g). A minibody derived from a second anti-p185HER2 antibody (trastuzumab; hu4D5v8) was also made. Tumor uptakes, evaluated by quantitative microPET using 64Cu-DOTA hu4D5v8 minibody, were 4.2 ± 0.5% ID/g. Furthermore, in non-tumor-bearing mice, 111In-DOTA hu4D5v8 minibody exhibited similar elevated uptake in the kidneys (28.4 ± 6.5% ID/g). Immunohistochemical staining of kidneys from non-tumor-bearing mice showed strong specific staining of the proximal tubules, and Western blot analysis of kidney lysate confirmed the presence of cross-reactive antigen. To further improve tumor uptake and normal tissue distribution, a larger hu4D5v8 fragment [(scFv-CH2-CH3)2; 105 kDa] was made, engineered to exhibit rapid clearance kinetics. This fragment, when evaluated by microPET, exhibited improved tumor targeting (12.2 ± 2.4% ID/g) and reduced kidney uptake (13.1 ± 1.5% ID/g). Thus, by manipulating the size and format of anti-p185 antibody fragments, the kidney activity was reduced and high or low expression of p185HER2 in xenografts could be distinguished by microPET imaging. PMID:15994969

  20. X-ray iron-line emission from the SN 185 remnant

    NASA Technical Reports Server (NTRS)

    Winkler, P. F.

    1979-01-01

    Radio and optical research was carried out in order to show that the supernova remnant RCW86 is a remnant of the earliest supernova event ever recorded in history (185 AD). The results are as follows: (1) an iron-line emission was found at 6.7 keV; (2) the temperature measured from HEAO-1 was approximately 6 keV; and (3) the equivalent width was consistent within the uncertainties with a cosmic iron abundance. These results support the identification of the supernova remnant RCW86 (it's X-ray source) with the historic supernova event.