Effects of LEO Environment on Tensile Properties of PEEK Films

NASA Astrophysics Data System (ADS)

Nakamura, Takashi; Nakamura, Hiroshi; Shimamura, Hiroyuki

2009-01-01

To clarify the effects of space environment on mechanical properties of polymer, exposure experiments were conducted utilizing the International Space Station Russian Service Module. Poly-ether-ether-ketone (PEEK) films under tensile stress were exposed to low Earth orbit (LEO) environment, and reference samples were irradiated with atomic oxygen (AO), electron beam (EB), and ultraviolet light (UV) in ground facilities. By comparing the results of flight and ground tests, the degradation behavior and the influential factors in LEO were investigated. The following results were obtained. (1) UV was found to be the harshest factor in LEO on tensile properties, since it decreased elongation to 15% of pristine sample after 46-months exposure. (2) AO in LEO eroded the specimen surface with a cone-like morphology and reduced the thickness; however, it had no significant effect on tensile properties. (3) EB irradiation in LEO had no measurable effects on the material properties.

System using leo satellites for centimeter-level navigation

NASA Technical Reports Server (NTRS)

Rabinowitz, Matthew (Inventor); Parkinson, Bradford W. (Inventor); Cohen, Clark E. (Inventor); Lawrence, David G. (Inventor)

2002-01-01

Disclosed herein is a system for rapidly resolving position with centimeter-level accuracy for a mobile or stationary receiver [4]. This is achieved by estimating a set of parameters that are related to the integer cycle ambiguities which arise in tracking the carrier phase of satellite downlinks [5,6]. In the preferred embodiment, the technique involves a navigation receiver [4] simultaneously tracking transmissions [6] from Low Earth Orbit Satellites (LEOS) [2] together with transmissions [5] from GPS navigation satellites [1]. The rapid change in the line-of-sight vectors from the receiver [4] to the LEO signal sources [2], due to the orbital motion of the LEOS, enables the resolution with integrity of the integer cycle ambiguities of the GPS signals [5] as well as parameters related to the integer cycle ambiguity on the LEOS signals [6]. These parameters, once identified, enable real-time centimeter-level positioning of the receiver [4]. In order to achieve high-precision position estimates without the use of specialized electronics such as atomic clocks, the technique accounts for instabilities in the crystal oscillators driving the satellite transmitters, as well as those in the reference [3] and user [4] receivers. In addition, the algorithm accommodates as well as to LEOS that receive signals from ground-based transmitters, then re-transmit frequency-converted signals to the ground.

LoWMob: Intra-PAN Mobility Support Schemes for 6LoWPAN

PubMed Central

Bag, Gargi; Raza, Muhammad Taqi; Kim, Ki-Hyung; Yoo, Seung-Wha

2009-01-01

Mobility in 6LoWPAN (IPv6 over Low Power Personal Area Networks) is being utilized in realizing many applications where sensor nodes, while moving, sense and transmit the gathered data to a monitoring server. By employing IEEE802.15.4 as a baseline for the link layer technology, 6LoWPAN implies low data rate and low power consumption with periodic sleep and wakeups for sensor nodes, without requiring them to incorporate complex hardware. Also enabling sensor nodes with IPv6 ensures that the sensor data can be accessed anytime and anywhere from the world. Several existing mobility-related schemes like HMIPv6, MIPv6, HAWAII, and Cellular IP require active participation of mobile nodes in the mobility signaling, thus leading to the mobility-related changes in the protocol stack of mobile nodes. In this paper, we present LoWMob, which is a network-based mobility scheme for mobile 6LoWPAN nodes in which the mobility of 6LoWPAN nodes is handled at the network-side. LoWMob ensures multi-hop communication between gateways and mobile nodes with the help of the static nodes within a 6LoWPAN. In order to reduce the signaling overhead of static nodes for supporting mobile nodes, LoWMob proposes a mobility support packet format at the adaptation layer of 6LoWPAN. Also we present a distributed version of LoWMob, named as DLoWMob (or Distributed LoWMob), which employs Mobility Support Points (MSPs) to distribute the traffic concentration at the gateways and to optimize the multi-hop routing path between source and destination nodes in a 6LoWPAN. Moreover, we have also discussed the security considerations for our proposed mobility schemes. The performance of our proposed schemes is evaluated in terms of mobility signaling costs, end-to-end delay, and packet success ratio. PMID:22346730

LoWMob: Intra-PAN Mobility Support Schemes for 6LoWPAN.

PubMed

Bag, Gargi; Raza, Muhammad Taqi; Kim, Ki-Hyung; Yoo, Seung-Wha

2009-01-01

Mobility in 6LoWPAN (IPv6 over Low Power Personal Area Networks) is being utilized in realizing many applications where sensor nodes, while moving, sense and transmit the gathered data to a monitoring server. By employing IEEE802.15.4 as a baseline for the link layer technology, 6LoWPAN implies low data rate and low power consumption with periodic sleep and wakeups for sensor nodes, without requiring them to incorporate complex hardware. Also enabling sensor nodes with IPv6 ensures that the sensor data can be accessed anytime and anywhere from the world. Several existing mobility-related schemes like HMIPv6, MIPv6, HAWAII, and Cellular IP require active participation of mobile nodes in the mobility signaling, thus leading to the mobility-related changes in the protocol stack of mobile nodes. In this paper, we present LoWMob, which is a network-based mobility scheme for mobile 6LoWPAN nodes in which the mobility of 6LoWPAN nodes is handled at the network-side. LoWMob ensures multi-hop communication between gateways and mobile nodes with the help of the static nodes within a 6LoWPAN. In order to reduce the signaling overhead of static nodes for supporting mobile nodes, LoWMob proposes a mobility support packet format at the adaptation layer of 6LoWPAN. Also we present a distributed version of LoWMob, named as DLoWMob (or Distributed LoWMob), which employs Mobility Support Points (MSPs) to distribute the traffic concentration at the gateways and to optimize the multi-hop routing path between source and destination nodes in a 6LoWPAN. Moreover, we have also discussed the security considerations for our proposed mobility schemes. The performance of our proposed schemes is evaluated in terms of mobility signaling costs, end-to-end delay, and packet success ratio.

Leo Commercial Market Projects (1997)

DOT National Transportation Integrated Search

1997-07-25

The Federal Aviation Administration's Associate Administrator for Commercial : Space Transportation (AST) has prepared projections of the low Earth orbit : (LEO) commercial payload and launch markets for the period between 1997 and : 2006. This asses...

Leo Commercial Market Projections (1996)

DOT National Transportation Integrated Search

1996-04-05

The Office of the Associate Administrator for Commercial Space Transportation OCST) of the Federal Aviation Administration (FAA) has prepared the attached projections of the Low Earth Orbit (LEO) commercial payload and launch markets for the period b...

AGB stars in Leo P and their use as metallicity probes

NASA Astrophysics Data System (ADS)

Lee, Chien-Hsiu

2016-09-01

Leo P is the most metal-poor yet star-forming galaxy in the local volume, and has the potential to serve as a local counterpart to interpret the properties of distant galaxies in the early universe. We present a comprehensive search of asymptotic giant branch (AGB) stars in Leo P using deep infrared imaging. AGB stars are the major dust contributors; the metal poor nature of Leo P can help to shed light on the dust formation process in very low-metallicity environments, similar to the early Universe. We select and classify oxygen-rich and carbon-rich candidate AGB stars using J - K versus K colour-magnitude diagram. To filter out contaminations from background galaxies, we exploit the high-resolution Hubble Space Telescope imaging and identify 9 oxygen-rich AGBs and 13 carbon-rich AGB stars in Leo P. We then use the ratio of carbon-rich and oxygen-rich AGB stars (C/M ratio) as an indicator of on-site metallicity and derive the global metallicity [Fe/H] = -1.8 dex for Leo P, in good agreement with previous studies using isochrone fitting. Follow-up observations of these Leo P AGB stars in the mid-infrared [e.g. Spitzer, James Webb Space Telescope (JWST)] will be invaluable to measure the dust formation rates using Spectral energy distribution (SED) fitting.

Hubble Peers into the Mouth of Leo A

NASA Image and Video Library

2017-12-08

At first glance, this NASA/ESA Hubble Space Telescope image seems to show an array of different cosmic objects, but the speckling of stars shown here actually forms a single body — a nearby dwarf galaxy known as Leo A. Its few million stars are so sparsely distributed that some distant background galaxies are visible through it. Leo A itself is at a distance of about 2.5 million light-years from Earth and a member of the Local Group of galaxies; a group that includes the Milky Way and the well-known Andromeda galaxy. Astronomers study dwarf galaxies because they are very numerous and are simpler in structure than their giant cousins. However, their small size makes them difficult to study at great distances. As a result, the dwarf galaxies of the Local Group are of particular interest, as they are close enough to study in detail. As it turns out, Leo A is a rather unusual galaxy. It is one of the most isolated galaxies in the Local Group, has no obvious structural features beyond being a roughly spherical mass of stars, and shows no evidence for recent interactions with any of its few neighbors. However, the galaxy’s contents are overwhelmingly dominated by relatively young stars, something that would normally be the result of a recent interaction with another galaxy. Around 90% of the stars in Leo A are less than eight billion years old — young in cosmic terms! This raises a number of intriguing questions about why star formation in Leo A did not take place on the “usual” timescale, but instead waited until it was good and ready. Image credit: ESA/Hubble & NASA; Acknowledgment: Judy Schmidt

A DEEPER LOOK AT LEO IV: STAR FORMATION HISTORY AND EXTENDED STRUCTURE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sand, David J.; Seth, Anil; Olszewski, Edward W.

We present MMT/Megacam imaging of the Leo IV dwarf galaxy in order to investigate its structure and star formation history, and to search for signs of association with the recently discovered Leo V satellite. Based on parameterized fits, we find that Leo IV is round, with {epsilon} < 0.23 (at the 68% confidence limit) and a half-light radius of r{sub h} {approx_equal} 130 pc. Additionally, we perform a thorough search for extended structures in the plane of the sky and along the line of sight. We derive our surface brightness detection limit by implanting fake structures into our catalog withmore » stellar populations identical to that of Leo IV. We show that we are sensitive to stream-like structures with surface brightness {mu}{sub r} {approx}< 29.6 mag arcsec{sup -2}, and at this limit we find no stellar bridge between Leo IV (out to a radius of {approx}0.5 kpc) and the recently discovered, nearby satellite Leo V. Using the color-magnitude fitting package StarFISH, we determine that Leo IV is consistent with a single age ({approx}14 Gyr), single metallicity ([Fe/H] {approx} -2.3) stellar population, although we cannot rule out a significant spread in these values. We derive a luminosity of M{sub V} = -5.5 {+-} 0.3. Studying both the spatial distribution and frequency of Leo IV's 'blue plume' stars reveals evidence for a young ({approx}2 Gyr) stellar population which makes up {approx}2% of its stellar mass. This sprinkling of star formation, only detectable in this deep study, highlights the need for further imaging of the new Milky Way satellites along with theoretical work on the expected, detailed properties of these possible 'reionization fossils'.« less

A Deeper Look at Leo IV: Star Formation History and Extended Structure

NASA Astrophysics Data System (ADS)

Sand, David J.; Seth, Anil; Olszewski, Edward W.; Willman, Beth; Zaritsky, Dennis; Kallivayalil, Nitya

2010-07-01

We present MMT/Megacam imaging of the Leo IV dwarf galaxy in order to investigate its structure and star formation history, and to search for signs of association with the recently discovered Leo V satellite. Based on parameterized fits, we find that Leo IV is round, with epsilon < 0.23 (at the 68% confidence limit) and a half-light radius of rh ~= 130 pc. Additionally, we perform a thorough search for extended structures in the plane of the sky and along the line of sight. We derive our surface brightness detection limit by implanting fake structures into our catalog with stellar populations identical to that of Leo IV. We show that we are sensitive to stream-like structures with surface brightness μ r <~ 29.6 mag arcsec-2, and at this limit we find no stellar bridge between Leo IV (out to a radius of ~0.5 kpc) and the recently discovered, nearby satellite Leo V. Using the color-magnitude fitting package StarFISH, we determine that Leo IV is consistent with a single age (~14 Gyr), single metallicity ([Fe/H] ~ -2.3) stellar population, although we cannot rule out a significant spread in these values. We derive a luminosity of MV = -5.5 ± 0.3. Studying both the spatial distribution and frequency of Leo IV's "blue plume" stars reveals evidence for a young (~2 Gyr) stellar population which makes up ~2% of its stellar mass. This sprinkling of star formation, only detectable in this deep study, highlights the need for further imaging of the new Milky Way satellites along with theoretical work on the expected, detailed properties of these possible "reionization fossils." Observations reported here were obtained at the MMT observatory, a joint facility of the Smithsonian Institution and the University of Arizona.

PCVs Estimation and their Impacts on Precise Orbit Determination of LEOs

NASA Astrophysics Data System (ADS)

Chunmei, Z.; WANG, X.

2017-12-01

In the last decade the precise orbit determination (POD) based on GNSS, such as GPS, has been considered as one of the efficient methods to derive orbits of Low Earth Orbiters (LEOs) that demand accuracy requirements. The Earth gravity field recovery and its related researches require precise dynamic orbits of LEOs. With the improvements of GNSS satellites' orbit and clock accuracy, the algorithm optimization and the refinement of perturbation force models, the antenna phase-center variations (PCVs) of space-borne GNSS receiver have become an increasingly important factor that affects POD accuracy. A series of LEOs such as HY-2, ZY-3 and FY-3 with homebred space-borne GNSS receivers have been launched in the past several years in China. Some of these LEOs load dual-mode GNSS receivers of GPS and BDS signals. The reliable performance of these space-borne receivers has been establishing an important foundation for the future launches of China gravity satellites. Therefore, we first evaluate the data quality of on-board GNSS measurement by examining integrity, multipath error, cycle slip ratio and other quality indices. Then we determine the orbits of several LEOs at different altitudes by the reduced dynamic orbit determination method. The corresponding ionosphere-free carrier phase post-fit residual time series are obtained. And then we establish the PCVs model by the ionosphere-free residual approach and analyze the effects of antenna phase-center variation on orbits. It is shown that orbit accuracy of LEO satellites is greatly improved after in-flight PCV calibration. Finally, focus on the dual-mode receiver of FY-3 satellite we analyze the quality of onboard BDS data and then evaluate the accuracy of the FY-3 orbit determined using only BDS measurement onboard. The accuracy of LEO satellites orbit based on BDS would be well improved with the global completion of BDS by 2020.

The Elusive Old Population of the Dwarf Spheroidal Galaxy Leo I.

PubMed

Held; Saviane; Momany; Carraro

2000-02-20

We report the discovery of a significant old population in the dwarf spheroidal (dSph) galaxy Leo I as a result of a wide-area search with the ESO New Technology Telescope. Studies of the stellar content of Local Group dwarf galaxies have shown the presence of an old stellar population in almost all of the dwarf spheroidal galaxies. The only exception was Leo I, which alone appeared to have delayed its initial star formation episode until just a few gigayears ago. The color-magnitude diagram of Leo I now reveals an extended horizontal branch, unambiguously indicating the presence of an old, metal-poor population in the outer regions of this galaxy. Yet we find little evidence for a stellar population gradient, at least outside R>2' (0.16 kpc), since the old horizontal branch stars of Leo I are radially distributed as their more numerous intermediate-age helium-burning counterparts. The discovery of a definitely old population in the predominantly young dwarf spheroidal galaxy Leo I points to a sharply defined first epoch of star formation common to all of the Local Group dSph galaxies as well as to the halo of the Milky Way.

Lunar Exploration Orbiter (LEO)

NASA Astrophysics Data System (ADS)

Jaumann, R.; Spohn, T.; Hiesinger, H.; Jessberger, E. K.; Neukum, G.; Oberst, J.; Helbert, J.; Christensen, U.; Keller, H. U.; Mall, U.; Böhnhardt, H.; Hartogh, P.; Glassmeier, K.-H.; Auster, H.-U.; Moreira, A.; Werner, M.; Pätzold, M.; Palme, H.; Wimmer-Schweingruber, R.; Mandea, M.; Lesur, V.; Häusler, B.; Hördt, A.; Eichentopf, K.; Hauber, E.; Hoffmann, H.; Köhler, U.; Kührt, E.; Michaelis, H.; Pauer, M.; Sohl, F.; Denk, T.; van Gasselt, S.

2007-08-01

The Moon is an integral part of the Earth-Moon system, it is a witness to more than 4.5 b. y. of solar system history, and it is the only planetary body except Earth for which we have samples from known locations. The Moon is our closest companion and can easily be reached from Earth at any time, even with a relatively modest financial budget. Consequently, the Moon was the first logical step in the exploration of our solar system before we pursued more distant targets such as Mars and beyond. The vast amount of knowledge gained from the Apollo and other lunar missions of the late 1960's and early 1970's demonstrates how valuable the Moon is for the understanding of our planetary system. Even today, the Moon remains an extremely interesting target scientifically and technologically, as ever since, new data have helped to address some of our questions about the Earth-Moon system, many questions remained. Therefore, returning to the Moon is the critical stepping-stone to further exploring our immediate planetary neighborhood. In this concept study, we present scientific and technological arguments for a national German lunar mission, the Lunar Explorations Orbiter (LEO). Numerous space-faring nations have realized and identified the unique opportunities related to lunar exploration and have planned missions to the Moon within the next few years. Among these missions, LEO will be unique, because it will globally explore the Moon in unprecedented spatial and spectral resolution. LEO will significantly improve our understanding of the lunar surface composition, surface ages, mineralogy, physical properties, interior, thermal history, gravity field, regolith structure, and magnetic field. The Lunar Explorations Orbiter will carry an entire suite of innovative, complementary technologies, including high-resolution camera systems, several spectrometers that cover previously unexplored parts of the electromagnetic spectrum over a broad range of wavelengths, microwave and

THE ARECIBO LEGACY FAST ALFA SURVEY. IX. THE LEO REGION H I CATALOG, GROUP MEMBERSHIP, AND THE H I MASS FUNCTION FOR THE LEO I GROUP

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stierwalt, Sabrina; Haynes, Martha P.; Giovanelli, Riccardo

We present the catalog of H I sources extracted from the ongoing Arecibo Legacy Fast ALFA (ALFALFA) extragalactic H I line survey, found within the sky region bounded by 9{sup h}36{sup m} < {alpha} < 11{sup h}36{sup m} and +08{sup 0} < {delta} < +12{sup 0}. The H I catalog presented here for this 118 deg{sup 2} region is combined with the ones derived from surrounding regions also covered by the ALFALFA survey to examine the large-scale structure in the complex Leo region. Because of the combination of wide sky coverage and superior sensitivity, spatial and spectral resolution, the ALFALFAmore » H I catalog of the Leo region improves significantly on the numbers of low H I mass sources as compared with those found in previous H I surveys. The H I mass function of the Leo I group presented here is dominated by low-mass objects: 45 of the 65 Leo I members have M{sub H{sub l}}<10{sup 8} M-odot, yielding tight constraints on the low-mass slope of the Leo I H I mass function. The best-fit slope is {alpha} {approx_equal} -1.41 + 0.2 - 0.1. A direct comparison between the ALFALFA H I line detections and an optical search of the Leo I region proves the advantage of the ALFALFA strategy in finding low-mass, gas-rich dwarfs. These results suggest the existence of a significant population of low surface brightness, gas-rich, yet still very low H I mass galaxies, and may reflect the same type of morphological segregation as is seen in the Local Group. While the low-mass end slope of the Leo I H I mass function is steeper than that determined for luminosity functions of the group, the slope still falls short of the values predicted by simulations of structure formation in the lambda cold dark matter paradigm.« less

Geocenter variations derived from a combined processing of LEO- and ground-based GPS observations

NASA Astrophysics Data System (ADS)

Männel, Benjamin; Rothacher, Markus

2017-08-01

GNSS observations provided by the global tracking network of the International GNSS Service (IGS, Dow et al. in J Geod 83(3):191-198, 2009) play an important role in the realization of a unique terrestrial reference frame that is accurate enough to allow a detailed monitoring of the Earth's system. Combining these ground-based data with GPS observations tracked by high-quality dual-frequency receivers on-board low earth orbiters (LEOs) is a promising way to further improve the realization of the terrestrial reference frame and the estimation of geocenter coordinates, GPS satellite orbits and Earth rotation parameters. To assess the scope of the improvement on the geocenter coordinates, we processed a network of 53 globally distributed and stable IGS stations together with four LEOs (GRACE-A, GRACE-B, OSTM/Jason-2 and GOCE) over a time interval of 3 years (2010-2012). To ensure fully consistent solutions, the zero-difference phase observations of the ground stations and LEOs were processed in a common least-squares adjustment, estimating all the relevant parameters such as GPS and LEO orbits, station coordinates, Earth rotation parameters and geocenter motion. We present the significant impact of the individual LEO and a combination of all four LEOs on the geocenter coordinates. The formal errors are reduced by around 20% due to the inclusion of one LEO into the ground-only solution, while in a solution with four LEOs LEO-specific characteristics are significantly reduced. We compare the derived geocenter coordinates w.r.t. LAGEOS results and external solutions based on GPS and SLR data. We found good agreement in the amplitudes of all components; however, the phases in x- and z-direction do not agree well.

The impact of leading empowered organisations (LEO) on leadership development in nursing.

PubMed

Hancock, Helen; Campbell, Steve; Bignell, Pat; Kilgour, Julie

2005-01-01

This study sought to evaluate the impact and sustainability of the Leading Empowered Organisations (LEO) programme on the role of G Grade Nurse Managers, their colleagues and therefore on patient care at CHS. A qualitative, inductive research methodology, which employed 360-degree research evaluation, was used. A purposive sample of four G Grade Nurse Managers was included. Each G Grade and eight of each of their colleagues were interviewed. Data were analysed according to the principles of thematic analysis. There was evidence of a sustained impact of the LEO programme on G Grade Nurse Managers in relation to competence, action plans, delegation, communication strategies, problem solving, risk taking, leadership and management. The study also revealed a number of significant personal and contextual factors that affected the implementation of the LEO principles. Empowerment, or a lack of it, underpinned much of what occurred in the implementation of the LEO principles by the G Grades into practice. The findings indicated that both organisational and individual action is necessary to achieve leadership development. Organisations need to ensure that investment in leadership is not restricted to the LEO programme, but that it becomes a strategic priority.

Telemetry Tracking & Control (TT&C) - First TDRSS, then Commercial GEO & Big LEO and Now Through LEO

NASA Technical Reports Server (NTRS)

Morgan, Dwayne R.; Streich, Ron G.; Bull, Barton; Grant, Chuck; Power, Edward I. (Technical Monitor)

2001-01-01

The advent of low earth orbit (LEO) commercial communication satellites provides an opportunity to dramatically reduce Telemetry, Tracking and Control (TT&C) costs of launch vehicles, Unpiloted Aerial Vehicles (UAVs), Research Balloons and spacecraft by reducing or eliminating ground infrastructure. Personnel from the Goddard Space Flight Center's Wallops Flight Facility (GSFC\\WFF) have successfully used commercial Geostationary Earth Orbit (GEO) and Big LEO communications satellites for Long Duration Balloon Flight TT&C. The Flight Modem is a GSFC\\WFF Advanced Range Technology initiative (ARTI) designed to streamline TT&C capability in the user community of these scientific data gathering platforms at low cost. Making use of existing LEO satellites and adapting and ruggedized commercially available components; two-way, over the horizon communications may be established with these vehicles at great savings due to reduced infrastructure. Initially planned as a means for permitting GPS data for tracking and recovery of sounding rocket and balloon payloads, expectations are that the bandwidth can soon be expanded to allow more comprehensive data transfer. The system architecture which integrates antennas, GPS receiver, commercial satellite packet data modem and a single board computer with custom software is described and technical challenges are discussed along with the plan for their resolution. A three-phase testing and development plan is outlined and the current results are reported. Results and status of ongoing flight tests on aircraft and sounding rockets are reported. Future applications on these platforms and the potential for satellite support are discussed along with an analysis of cost effectiveness of this method vs. other tracking and data transmission schemes.

New Light-Time Curve of Eclipsing Binary AM Leo

NASA Astrophysics Data System (ADS)

Gorda, S. Yu.; Matveeva, E. A.

2017-12-01

We present 72 photoelectric and CCD times of minima of eclipsing binary AM Leo obtained mainly during at Kourovka Astronomical Observatory of the Ural Federal University in Russia. We obtained new values of period of 50.5 years and eccentricity of 0.28 of the orbit of the eclipsing pair around the mass center of the system AM Leo with the third body. These results have been received taking into account the times of minima taken from literature and obtained from to .

Study of LEO-SAT microwave link for broad-band mobile satellite communication system

NASA Technical Reports Server (NTRS)

Fujise, Masayuki; Chujo, Wataru; Chiba, Isamu; Furuhama, Yoji; Kawabata, Kazuaki; Konishi, Yoshihiko

1993-01-01

In the field of mobile satellite communications, a system based on low-earth-orbit satellites (LEO-SAT's) such as the Iridium system has been proposed. The LEO-SAT system is able to offer mobile telecommunication services in high-latitude areas. Rain degradation, fading and shadowing are also expected to be decreased when the system is operated at a high elevation angle. Furthermore, the propagation delay generated in the LEO-SAT system is less pronounced than that in the geostationary orbit satellite (GEO-SAT) system and, in voice services, the effect of the delay is almost negligible. We proposed a concept of a broad-band mobile satellite communication system with LEO-SAT's and Optical ISL. In that system, a fixed L-band (1.6/1.5 GHz) multibeam is used to offer narrow band service to the mobile terminals in the entire area covered by a LEO-SAT and steerable Ka-band (30/20 GHz) spot beams are used for the wide band service. In this paper, we present results of a study of LEO-SAT microwave link between a satellite and a mobile terminal for a broad-band mobile satellite communication system. First, the results of link budget calculations are presented and the antennas mounted on satellites are shown. For a future mobile antenna technology, we also show digital beamforming (DBF) techniques. DBF, together with modulation and/or demodulation, is becoming a key technique for mobile antennas with advanced functions such as antenna pattern calibration, correction, and radio interference suppression. In this paper, efficient DBF techniques for transmitting and receiving are presented. Furthermore, an adaptive array antenna system suitable for this LEO-SAT is presented.

Water vapor retrieval by LEO and GEO SAR: techniques and performance evaluation.

NASA Astrophysics Data System (ADS)

Fermi, Alessandro; Silvio Marzano, Frank; Monti Guarnieri, Andrea; Pierdicca, Nazzareno; Realini, Eugenio; Venuti, Giovanna

2016-04-01

The millimetric sensitivity of SAR interferometry has been proved fruitful in estimating water-vapor maps, that can then be processed into higher level ZWD and PWV products. In the paper, we consider two different SAR surveys: Low Earth Orbiting (LEO) SAR, like ESA Sentinel-1, and Geosynchronous Earth Orbiting SAR. The two system are complementary, where LEO coverage is world-wide, while GEO is regional. On the other hand, LEO revisit is daily-to weekly, whereas GEO provides images in minutes to hours. Finally, LEO synthetic aperture is so short, less than a second, that the water-vapor is mostly frozen, whereas in the long GEO aperture the atmospheric phase screen would introduce a total decorrelation, if not compensated for. In the paper, we first review the Differential Interferometric techniques to get differential delay maps - to be then converted into water-vapor products, and then evaluate the quality in terms of geometric resolution, sensitivity, percentage of scene coverage, revisit, by referring to L and C band system, for both LEO and GEO. Finally, we discuss an empirical model for time-space variogram, and show a preliminary validation by campaign conducted with Ground Based Radar, as a proxy of GEO-SAR, capable of continuous scanning wide areas (up to 15 km) with metric resolution.

NASA-STD-4005 and NASA-HDBK-4006, LEO Spacecraft Solar Array Charging Design Standard

NASA Technical Reports Server (NTRS)

Ferguson, Dale C.

2007-01-01

Two new NASA Standards are now official. They are the NASA LEO Spacecraft Charging Design Standard (NASA-STD-4005) and the NASA LEO Spacecraft Charging Design Handbook (NASA-HDBK-4006). They give the background and techniques for controlling solar array-induced charging and arcing in LEO. In this paper, a brief overview of the new standards is given, along with where they can be obtained and who should be using them.

Operation of commercial R3000 processors in the low earth orbit (LEO) space environment

NASA Astrophysics Data System (ADS)

Kaschmitter, J. L.; Shaeffer, D. L.; Colella, N. J.; McKnett, C. L.; Coakley, P. G.

1991-12-01

Spacecraft processors must operate with minimal degradation of performance in the LEO radiation environment, which includes the effects of total accumulated ionizing dose and single event phenomena (SEP) caused by protons and cosmic rays. Commercially available microprocessors can offer a number of advantages relative to radiation-hardened devices but are not normally designed to tolerate effects induced by the LEO environment. Extensive testing of the MIPS R3000 Reduced Instruction Set Computer (RISC) microprocessor family for operation in LEO environments is reported. The authors have characterized total dose and SEP effects for altitudes and inclinations of interest to systems operating in LEO, and they postulate techniques for detection and alleviation of SEP effects based on experimental results.

Materials selection for long life in LEO: A critical evaluation of atomic oxygen testing with thermal atom systems

NASA Technical Reports Server (NTRS)

Koontz, S. L.; Kuminecz, J.; Leger, L.; Nordine, P.

1988-01-01

The use of thermal atom test methods as a materials selection and screening technique for low-Earth orbit (LEO) spacecraft is critically evaluated. The chemistry and physics of thermal atom environments are compared with the LEO environment. The relative reactivities of a number of materials determined to be in thermal atom environments are compared to those observed in LEO and in high quality LEO simulations. Reaction efficiencies measured in a new type of thermal atom apparatus are one-hundredth to one-thousandth those observed in LEO, and many materials showing nearly identical reactivities in LEO show relative reactivities differing by as much as a factor of 8 in thermal atom systems. A simple phenomenological kinetic model for the reaction of oxygen atoms with organic materials can be used to explain the differences in reactivity in different environments. Certain specific thermal test environments can be used as reliable materials screening tools. Using thermal atom methods to predict material lifetime in LEO requires direct calibration of the method against LEO data or high quality simulation data for each material.

An Update on the Effectiveness of Postmission Disposal in LEO

NASA Technical Reports Server (NTRS)

Liou, J.-C; Krisko, Paula

2013-01-01

Orbital debris mitigation measures have been developed to reduce the growth of the future debris population by the international space community over the past two decades. A major component in the overall mitigation strategy is postmission disposal (PMD). A key PMD element for the low Earth orbit (LEO, the region below 2000 km altitude) satellites is the 25-year decay rule. It is intended to limit the long-term presence of massive intact objects - rocket bodies (R/Bs) and spacecraft (S/C) in the environment. The effectiveness of the 25-year rule was well demonstrated and documented during the development of the mitigation measures. The orbital debris population in LEO, unfortunately, has significantly increased since that time. The objectives of this paper are to provide an updated assessment based on the 2012 LEO environment and to highlight the importance of the global compliance of the 25-year decay rule.

A novel data association scheme for LEO space debris surveillance based on a double fence radar system

NASA Astrophysics Data System (ADS)

Huang, Jian; Hu, Weidong; Xin, Qin; Guo, Weiwei

2012-12-01

The increasing amount of space debris threatens to seriously deteriorate and damage space-based instruments in Low Earth Orbit (LEO) environments. Therefore, LEO space debris surveillance systems must be developed to provide situational awareness in space and issue warnings of collisions with LEO space debris. In this paper, a double fence radar system is proposed as an emerging paradigm for LEO space debris surveillance. This system exhibits several unique and promising characteristics compared with existing surveillance systems. In this paper, we also investigate the data association scheme for LEO space debris surveillance based on a double fence radar system. We also perform a theoretical analysis of the performance of our proposed scheme. The superiority and the effectiveness of our novel data association scheme is demonstrated by experimental results. The data used in our experiments is the LEO space debris catalog produced by the North American Air Defense Command (NORAD) up to 2009, especially for scenarios with high densities of LEO space debris, which were primarily produced by the collisions between Iridium 33 and Cosmos 2251. We hope that our work will stimulate and benefit future work on LEO space debris surveillance approaches and enable construction of the double fence radar system.

The chemical abundances of the stellar populations in the Leo I and II dSph galaxies

NASA Astrophysics Data System (ADS)

Bosler, Tammy L.; Smecker-Hane, Tammy A.; Stetson, Peter B.

2007-06-01

We have obtained calcium abundances and radial velocities for 102 red giant branch (RGB) stars in the Leo I dwarf spheroidal galaxy (dSph) and 74 RGB stars in the Leo II dSph using the low-resolution spectrograph (LRIS) on the Keck I 10-m telescope. We report on the calcium abundances [Ca/H] derived from the strengths of the CaII triplet absorption lines at 8498, 8542 and 8662 Å in the stellar spectra using a new empirical CaII triplet calibration to [Ca/H]. The two galaxies have different average [Ca/H] values of -1.34 +/- 0.02 for Leo I and -1.65 +/- 0.02 for Leo II with intrinsic abundance dispersions of 1.2 and 1.0 dex, respectively. The typical random and total errors in derived abundances are 0.10 and 0.17 dex per star. For comparison to the existing literature, we also converted our CaII measurements to [Fe/H] on the scale of Carretta and Gratton (1997) though we discuss why this may not be the best determinant of metallicity; Leo I has a mean [Fe/H] = -1.34 and Leo II has a mean [Fe/H] = -1.59. The metallicity distribution function of Leo I is approximately Gaussian in shape with an excess at the metal-rich end, while that of Leo II shows an abrupt cut-off at the metal-rich end. The lower mean metallicity of Leo II is consistent with the fact that it has a lower luminosity, hence lower the total mass than Leo I; thus, the evolution of Leo II may have been affected more by mass lost in galactic winds. Our direct and independent measurement of the metallicity distributions in these dSph will allow a more accurate star-formation histories to be derived from future analysis of their colour-magnitude diagrams(CMDs). Data presented herein were obtained at the W.M. Keck Observatory, which is operated as a scientific partnership among the California Institute of Technology, the University of California and the National Aeronautics and Space Administration. The Observatory was made possible by the generous financial support of the W. M. Keck Foundation. E

Performance of Duplex Communication Between a LEO Satellite and Terrestrial Location Using a GEO Constellation

NASA Technical Reports Server (NTRS)

Robinson, Daryl C.; Konangi, Vijay K.; Wallett, Thomas M.

1998-01-01

A network comprised of a terrestrial site, a constellation of three GEO satellites and a LEO satellite is modeled and simulated. Continuous communication between the terrestrial site and the LEO satellite is facilitated by the GEO satellites. The LEO satellite has the orbital characteristics of the International Space Station. Communication in the network is based on TCP/IP over ATM, with the ABR service category providing the QoS, at OC-3 data rate. The OSPF protocol is used for routing. We simulate FTP file transfers, with the terrestrial site serving as the client and the LEO satellite being the server. The performance characteristics are presented.

TT and C - First TDRSS, Then Commercial GEO and Big LEO and Now through LEO

NASA Technical Reports Server (NTRS)

Morgan, Dwayne; Bull, Barton; Grant, Charles; Streich, Ronald; Powers, Edward I. (Technical Monitor)

2001-01-01

The advent of low earth orbit (LEO) commercial communications satellites provides an opportunity to dramatically reduce Telemetry Tracking and Control (TT&C) costs of launch vehicles and Unpiloted Aerial Vehicles (UAVs) by reducing or eliminating ground infrastructure. Personnel from the Goddard Space Flight Center Wallops Flight Facility (GSFC/WFF) in Virginia have successfully used commercial GEO & Big LEO communications satellites for Long Duration Balloon flight TT&C. In addition, TDRSS capability for these balloons has been developed by WFF for the Ultra Long Duration Balloons with the first test flight launch in January 2001 for one global circumnavigation at 120,000 feet altitude launched from Alice Springs. Australia. Numerous other low cost applications can new utilize the commercial LEO satellites for TT&C. The Flight Modern became a GSFC/WFF Advanced Range Technology Initiative (ARTI) in an effort to streamline TT&C capability to the user community at low cost. Phase I ground tests of The Flight Modem verified downlink communications quality of service and measured transmission latencies. These tests were completed last year, Phase II consisting of aircraft flight tests provide much of the data presented in this paper. Phase III of the Flight Modern baseline test program is a demonstration of the ruggedized version of the WFF Flight Modem flown on one sounding rocket launched from Sweden. Flights of opportunity have been and are being actively pursued with other centers, ranges and users at universities. The WFF goal is to reduce TT&C costs by providing a low cost COTS Flight Modem with a User Handbook containing system capability and limitation descriptions. Additionally, since data transmission is by packetized Internet Protocol (IP), data can be received and commands initialed from practically any location with no infrastructure. The WFF, like most ranges, has been using GPS receivers on sounding rockets and long duration balloons for several years

Impact of GNSS orbit modeling on LEO orbit and gravity field determination

NASA Astrophysics Data System (ADS)

Arnold, Daniel; Meyer, Ulrich; Sušnik, Andreja; Dach, Rolf; Jäggi, Adrian

2017-04-01

On January 4, 2015 the Center for Orbit Determination in Europe (CODE) changed the solar radiation pressure modeling for GNSS satellites to an updated version of the empirical CODE orbit model (ECOM). Furthermore, since September 2012 CODE operationally computes satellite clock corrections not only for the 3-day long-arc solutions, but also for the non-overlapping 1-day GNSS orbits. This provides different sets of GNSS products for Precise Point Positioning, as employed, e.g., in the GNSS-based precise orbit determination of low Earth orbiters (LEOs) and the subsequent Earth gravity field recovery from kinematic LEO orbits. While the impact of the mentioned changes in orbit modeling and solution strategy on the GNSS orbits and geophysical parameters was studied in detail, their implications on the LEO orbits were not yet analyzed. We discuss the impact of the update of the ECOM and the influence of 1-day and 3-day GNSS orbit solutions on zero-difference LEO orbit and gravity field determination, where the GNSS orbits and clock corrections, as well as the Earth rotation parameters are introduced as fixed external products. Several years of kinematic and reduced-dynamic orbits for the two GRACE LEOs are computed with GNSS products based on both the old and the updated ECOM, as well as with 1- and 3-day GNSS products. The GRACE orbits are compared by means of standard validation measures. Furthermore, monthly and long-term GPS-only and combined GPS/K-band gravity field solutions are derived from the different sets of kinematic LEO orbits. GPS-only fields are validated by comparison to combined GPS/K-band solutions, while the combined solutions are validated by analysis of the formal errors, as well as by comparing them to the combined GRACE solutions of the European Gravity Service for Improved Emergency Management (EGSIEM) project.

Low Earth Orbit (LEO) Commercial Market Projections

DOT National Transportation Integrated Search

1995-05-16

This study assesses the possible number of small commercial satellites to be : launched to Low Earth Orbit (LEO) in the period 1995-2005. The information : provided reflects an Office of Commercial Space Transportation (OCST) : assessment of overall ...

Geocenter Coordinates from a Combined Processing of LEO and Ground-based GPS Observations

NASA Astrophysics Data System (ADS)

Männel, Benjamin; Rothacher, Markus

2017-04-01

The GPS observations provided by the global IGS (International GNSS Service) tracking network play an important role for the realization of a unique terrestrial reference frame that is accurate enough to allow the monitoring of the Earth's system. Combining these ground-based data with GPS observations tracked by high-quality dual-frequency receivers on-board Low Earth Orbiters (LEO) might help to further improve the realization of the terrestrial reference frame and the estimation of the geocenter coordinates, GPS satellite orbits and Earth rotation parameters (ERP). To assess the scope of improvement, we processed a network of 50 globally distributed and stable IGS-stations together with four LEOs (GRACE-A, GRACE-B, OSTM/Jason-2 and GOCE) over a time interval of three years (2010-2012). To ensure fully consistent solutions the zero-difference phase observations of the ground stations and LEOs were processed in a common least-square adjustment, estimating GPS orbits, LEO orbits, station coordinates, ERPs, site-specific tropospheric delays, satellite and receiver clocks and ambiguities. We present the significant impact of the individual LEOs and a combination of all four LEOs on geocenter coordinates derived by using a translational approach (also called network shift approach). In addition, we present geocenter coordinates derived from the same set of GPS observations by using a unified approach. This approach combines the translational and the degree-one approach by estimating translations and surface deformations simultaneously. Based on comparisons against each other and against geocenter time series derived by other techniques the effect of the selected approach is assessed.

Leo P: A very low-mass, extremely metal-poor, star-forming galaxy

NASA Astrophysics Data System (ADS)

McQuinn, Kristen B.; Leo P Team

2017-01-01

Leo P is a low-luminosity dwarf galaxy just outside the Local Group with properties that make it an ideal probe of galaxy evolution at the faint-end of the luminosity function. Using combined data from 2 Hubble Space Telescope (HST) observing campaigns, the Very Large Array, the Spitzer Space telescope, as well as ground based data, we have constructed a robust evolutionary picture of Leo P. Leo P is one the most metal-poor, gas-rich galaxies ever discovered, has a stellar mass of a 5x105 Msun, comparable gas mass, and a single HII region. The star formation history reconstructed from the resolved stellar populations in Leo P shows it is unquenched, despite its very low mass. Based on the star formation history and metallicity measurements, the galaxy has lost 95% of its oxygen produced via nucleosynthesis, presumably to outflows. The neutral gas in the galaxy shows signs of rotation, although the velocity dispersion is comparable to the rotation velocity. Thus, Leo P bridges the gap between more massive dwarf irregular and less massive dwarf spheroidals on the baryonic Tully-Fisher relation. Furthermore, the galaxy hosts several, extremely dusty AGB candidates which will be probed with new HST and Spitzer observations. If confirmed as AGB stars, these may be our best local proxies for studying chemically unevolved star formation and subsequent dust production in metallicity environments comparable to the early universe.

Structure Activity Relationship Studies of Flavonoids as Potent Inhibitors of Human Platelet 12-hLO, Reticulocyte 15-hLO-1 and Prostate Epithelial 15-hLO-2

PubMed Central

Vasquez-Martinez, Yesseny; Ohri, Rachana V.; Kenyon, Victor; Holman, Theodore R.; Sepúlveda-Boza, Silvia

2007-01-01

Human lipoxygenase (hLO) isozymes have been implicated in a number of disease states and have attracted much attention with respect to their inhibition. One class of inhibitors, the flavonoids, have been shown to be potent lipoxygenase inhibitors but their study has been restricted to those compounds found in nature, which have limited structural variability. We have therefore carried out a comprehensive study to determine the structural requirements for flavonoid potency and selectivity against platelet 12-hLO, reticulocyte 15-hLO-1 and prostate epithelial 15-hLO-2. We conclude from this study that catechols are essential for high potency, that isoflavones and isoflavanones tend to select against 12-hLO, that isoflavans tend to select against 15-hLO-1, but few flavonoids target 15-hLO-2. PMID:17869117

Can Telescopes Help Leo Satellites Dodge Most Lethal Impacts?

NASA Astrophysics Data System (ADS)

GUDIEL, ANDREA; Carroll, Joseph; Rowe, David

2018-01-01

Authors: Joseph Carroll and David RoweABSTRACT LEO objects are tracked by radar because it works day and night, in all weather. This fits military interest in potentially hostile objects. There is less interest in objects too small to be credible active threats. But accidental hypervelocity impact by even 5-10 mm objects can disable most LEO satellites. Such “cm-class” objects greatly outnumber objects of military interest, and will cause most accidental impact losses.Under good viewing conditions, a sunlit 5mm sphere with 0.15 albedo at 800 km altitude is a 19th magnitude object. A ground-based 0.5m telescope tracking it against a 20 mag/arcsec2 sky can see it in seconds, and provide <1 arc-second alt/az fixes against the stars. A key question is how much of the “usually lethal” LEO debris population can be tracked frequently, accurately, and affordably enough to be avoided. The value of a conjunction warning service should scale with the number of lethal objects in its catalog. This should motivate a commercial service to find and catalog most lethal objects. There may already be >1 million such objects in LEO, nearly all debris fragments, mostly cm-class and at 600-1200 km altitude.Maintaining a ~million-item catalog requires a world-wide network of several dozen telescope sites with several telescopes at each site. Each telescope needs a mount capable of ~1,000,000 fast slews/year without wearing out.The paper discusses recent advances that make such a service far more feasible:1. Automated tasking and remote control of distributed telescope networks,2. Direct-drive mounts that can make millions of fast slews without wearing out,3. Telescope optics with low focal curvature that are in focus across large imagers,4. CMOS imagers with 95% peak QE and 1.5e- noise at 2E8 pix/sec readout rates,5. Methods for uncued detection of most lethal LEO debris (eg., >5 mm at 800 km),6. Initial orbit determination using 3 alt-az fixes made during the discovery pass,7

GFEChutes Lo-Fi

NASA Technical Reports Server (NTRS)

Gist, Emily; Turner, Gary; Shelton, Robert; Vautier, Mana; Shaikh, Ashraf

2013-01-01

NASA needed to provide a software model of a parachute system for a manned re-entry vehicle. NASA has parachute codes, e.g., the Descent Simulation System (DSS), that date back to the Apollo Program. Since the space shuttle did not rely on parachutes as its primary descent control mechanism, DSS has not been maintained or incorporated into modern simulation architectures such as Osiris and Antares, which are used for new mission simulations. GFEChutes Lo-Fi is an object-oriented implementation of conventional parachute codes designed for use in modern simulation environments. The GFE (Government Furnished Equipment), low-fidelity (Lo-Fi) parachute model (GFEChutes Lo-Fi) is a software package capable of modeling the effects of multiple parachutes, deployed concurrently and/or sequentially, on a vehicle during the subsonic phase of reentry into planetary atmosphere. The term "low-fidelity" distinguishes models that represent the parachutes as simple forces acting on the vehicle, as opposed to independent aerodynamic bodies. GFEChutes Lo-Fi was created from these existing models to be clean, modular, certified as NASA Class C software, and portable, or "plug and play." The GFE Lo-Fi Chutes Model provides basic modeling capability of a sequential series of parachute activities. Actions include deploying the parachute, changing the reefing on the parachute, and cutting away the parachute. Multiple chutes can be deployed at any given time, but all chutes in that case are assumed to behave as individually isolated chutes; there is no modeling of any interactions between deployed chutes. Drag characteristics of a deployed chute are based on a coefficient of drag, the face area of the chute, and the local dynamic pressure only. The orientation of the chute is approximately modeled for purposes of obtaining torques on the vehicle, but the dynamic state of the chute as a separate entity is not integrated - the treatment is simply an approximation. The innovation in GFEChutes

Reinforcement learning for resource allocation in LEO satellite networks.

PubMed

Usaha, Wipawee; Barria, Javier A

2007-06-01

In this paper, we develop and assess online decision-making algorithms for call admission and routing for low Earth orbit (LEO) satellite networks. It has been shown in a recent paper that, in a LEO satellite system, a semi-Markov decision process formulation of the call admission and routing problem can achieve better performance in terms of an average revenue function than existing routing methods. However, the conventional dynamic programming (DP) numerical solution becomes prohibited as the problem size increases. In this paper, two solution methods based on reinforcement learning (RL) are proposed in order to circumvent the computational burden of DP. The first method is based on an actor-critic method with temporal-difference (TD) learning. The second method is based on a critic-only method, called optimistic TD learning. The algorithms enhance performance in terms of requirements in storage, computational complexity and computational time, and in terms of an overall long-term average revenue function that penalizes blocked calls. Numerical studies are carried out, and the results obtained show that the RL framework can achieve up to 56% higher average revenue over existing routing methods used in LEO satellite networks with reasonable storage and computational requirements.

A photometric study of the dwarf spheroidal galaxies Leo IV and Bootes II

NASA Astrophysics Data System (ADS)

Cheng, Haw

A photometric study of the ultra-faint dwarf (UFD) galaxies Leo IV and Bootes II in the V and IC filters is here presented. The age of Leo IV relative to M92 were derived by fitting of Dartmouth isochrones, by a "standard" VHBTO method, and by the V HBTO method of VandenBerg et al. 2013. The age of Bootes II relative to M92 was derived by fitting of Dartmouth isochrones. Leo IV is found to be between 2 to 2.5 Gyr younger than M92 by these three methods. It is found to be predominantly old and metal poor and is well fit by isochrones of [Fe/H] = ---2.46 and [alpha/Fe] = 0.2 and 0.4. An age spread with a plausible value of ˜ 2 Gyr cannot be ruled out. A 10 Gyr old synthetic horizontal branch with [Fe/H] = ---1.70 and [alpha/Fe] of 0.2 is fit to Leo IV's red horizontal branch (RHB). The good fit of this model and its matching isochrone to Leo IV's CMD suggests that the RHB is real and not an observational artifact as proposed by Okamoto et al. 2012. Two RRab Lyraes previously observed by Moretti et al. 2009 were observed in Leo IV. One of the stars, V1, is observed to exhibit the Blazhko effect. No further RR Lyraes were uncovered in Leo IV. Comparison of the horizontal branch's observed V magnitude to the absolute magnitudes of the RR Lyraes yields a distance modulus of (m---M)0 = 21.01 +/- 0.07, in good agreement with previous studies. Leo IV's possible population of blue stragglers is found to show no signs of central concentration, though this study's sample and spatial coverage are too small for any detailed spatial distribution study. Bootes II's CMD is found to be consistent with that of a single age, mono-metallicity system. It is well fit by isochrones of [Fe/H] = ---1.79 and [alpha/Fe] = 0.2 and 0.4. Bootes II is found to be between 0.5 to 1.5 Gyr younger than M92. Distance was left as a free parameter in the fits. Bootes II is found to have distance modulus (m---M)0 lying between 18.02 to 18.15, in good agreement with previous studies. A single RRab Lyrae

AH Leo and the Blazhko Effect

NASA Astrophysics Data System (ADS)

Phillips, J.; Gay, P. L.

2004-12-01

We obtained 563 V-Band observations of AH Leo between January 27 and May 12, 2004. All observations were obtained with a 12-inch Schmidt-Cassegrain located on the island of Saipan, in the Commonwealth of the Northern Mariana Islands. We show that AH Leo is a type RRab RR Lyrae star with a minimum magnitude of V=14.658 magnitudes, a maximum amplitude of 0.989 magnitudes and a minimum amplitude of perhaps just 0.4 magnitudes. Its primary period is 0.4662609 days. Our observations also confirm the presence of the Blazhko effect, which had previously been detected by Smith and Gay (private communication) in 1993 and 1994. We estimate the Blazhko period to be roughly 20-days, however poor phase coverage at maximum light makes exact determination impossible. We also note that the bump during minimum, which is common in many RR Lyraes, varied throughout the Blazhko cycle, demonstrating amplitudes between 0 and 0.15 magnitudes. We would like to thank Sarah Maddison and Swinburne Astronomy Online for supporting this project

Overview of battery usage in NASA/GSFC LEO and GEO missions

NASA Technical Reports Server (NTRS)

Yi, Thomas

1989-01-01

In July, 1989, Cosmic Background Explorer (COBE) will be launched from a Delta rocket to study the big bang theory. The COBE, which is in a LEO/Polar orbit, will have two 20 Ah NiCd batteries, and 18 cells per battery, made by McDonnell Douglas Company. In December, 1989, National Oceanic and Atmospheric Administration (NOAA-D) will be launched from an Atlas rocket for weather observation purposes. NOAA-D, which is in a LEO/Polar morning orbit, will have two 26.5 Ah NiCd batteries, and 17 cells per battery, made by Ge-Astro East Windor. NOAA-I, which is scheduled for May, 1991 launch in a LEO/Polar afternoon orbit, will have three 26.5 Ah NiCd batteries, 17 cells per battery, made by GE-Astro East Windor. In April, 1990, Gamma Ray Observatory (GRO) will be launched from STS37 to study the gamma ray radiation phenomenon. GRO, which is in a LEO orbit, will have two modular power systems (MPS) made by McDonnell Douglas, each MPS consisting of three 50 Ah NiCd batteries, 22 cells per battery. In July, 1990, Geostationary Operational Environmental Satellite (GOES-I) will be launched from an Atlas I rocket for weather observation purposes. GOES-I, which is in a GEO orbit, will have two 12 Ah NiCd batteries, 28 cells per battery, made by Ford Aerospace and Communications Company. In December, 1990, Tracking and Data Relay Satellite (TDRS-E) will be launched from STS43 for communication purposes. TDRS-E, which is in a GEO orbit, will have three 40 Ah NiCd batteries, 24 cells per battery, made by TRW. In August, 1991, Extreme Ultraviolet Explorer (EUVE) will be launched from a Delta rocket. EUVE, which is in a LEO orbit, will have one modular power system (MPS) made by McDonnell Douglas. In December, 1991, Upper Atmosphere Research Satellite (UARS) will be launched from STS50 to study the Earth's ozone layer and other environmental concerns. UARS, which is in a 56 deg inclination LEO orbit, will have one modular power systems (MPS) made by McDonnell Douglas.

Optical Observation of LEO Debris Caused by Feng Yun 1C

NASA Astrophysics Data System (ADS)

Kurosaki, Hirohisa; Yanagisawa, Toshifumi; Nakajima, Atsushi

Many pieces of space debris are in low earth orbit (LEO), and may be a serious problem in the near future. They are very hazardous to spacecraft such as the ISS, in which humans stay for long periods. In January 2007, China performed an experimental destruction of the meteorological satellite FengYun-1C in low earth orbit using a ballistic missile. Optical instruments for space debris observation were installed on Mt. Nyukasa in Nagano Prefecture by JAXA, and the resulting low earth orbit debris was observed with the small telescope there. We have developed an image-processing technique, the line-detection method, to extract such effects as the streaks created by meteors, LEO satellites, and LEO debris. We succeeded in detecting the trajectories of specified FengYun-1C debris whose TLE were known. In this paper, the detection and observation of low earth orbit debris are discussed.

The Velocity Dispersion Profile of the Remote Dwarf Spheroidal Galaxy Leo I: A Tidal Hit and Run?

NASA Astrophysics Data System (ADS)

Mateo, Mario; Olszewski, Edward W.; Walker, Matthew G.

2008-03-01

We present new kinematic results for 387 stars near the Milky Way satellite dwarf spheroidal galaxy Leo I. Spectra were obtained with the Hectochelle multiobject echelle spectrograph on the MMT, centered in the optical near 5200 Å. From 297 repeat measurements of 108 stars, we estimate the mean velocity error (1 σ) of our sample to be 2.4 km s-1, with a systematic precision of <=1 km s-1. The final sample of 328 Leo I members gives a mean heliocentric velocity of 282.9 +/- 0.5 km s-1 and a dispersion of 9.2 +/- 0.4 km s-1. The dispersion profile of Leo I is flat to beyond its classical "tidal" radius. We fit the profile to various equilibrium dynamical models. We strongly rule out all models where mass follows light. Anisotropic Sérsic+NFW models fit the dispersion profile well, but isotropic models are ruled out at a 95% confidence level. Inside a projected radius of ~1040 pc, the mass and V-band mass-to-light ratio of Leo I from equilibrium models are in the ranges (5-7) × 107 M⊙ and 9-14 (solar units), respectively. Leo I members outside a "break radius" of Rb ~ 400'' (500 pc) exhibit significant velocity anisotropy, whereas stars interior to this radius are consistent with an isotropic velocity distribution. We interpret the break radius as the tidal radius of Leo I at perigalacticon some 1-2 Gyr ago. This interpretation accounts for the complex star formation history of Leo I, population segregation within the galaxy, and Leo I's large outward galactocentric velocity. The lack of evident tidal arms in Leo I suggests that the galaxy may have been injected into its present highly elliptical orbit by a third body a few Gyr before its last perigalacticon. This scenario is plausible within current hierarchical structure formation models.

Passive Optical Link Budget for LEO Space Surveillance

NASA Astrophysics Data System (ADS)

Wagner, P.; Hasenohr, T.; Hampf, D.; Sproll, F.; Humbert, L.; Rodmann, J.; Riede, W.

The rising space debris population is becoming an increasing risk for space assets. Even objects with the size of 10mm can cause major damages to active spacecraft. Especially the orbits around 800km high are densely populated with space debris objects. To assess the risk of collisions with active satellites, the Earth orbits need to be surveyed permanently. Space debris laser ranging systems for example can deliver highly accurate positional data for precise orbit determination. Therefor a priori information about the objects coarse trajectory is needed. Such initial orbit information can be provided by wide angle optical sensors. The Institute of Technical Physics at the German Aerospace Center in Stuttgart runs an observatory to perform passive as well as laser optical measurements to LEO objects. In order to detect unknown objects, a wide-angle imaging system with a field of view in the range of 5° to 15° equipped with an astronomical CCD camera and a commercial off the shelf (COTS) lens was designed to continuously observe the night sky for LEO objects. This paper presents the passive optical link budget for observing LEO objects to show the benefits and limits of the physical performance of an optical surveillance system. A compact COTS system is able to detect objects with a couple of decimeters in size while a large aperture telescope can detect objects with diameters below 10cm. Additionally, data captured by a passive optical staring system with a 10 cm aperture was analyzed. It is shown that 90% of all objects with a radar cross section larger than 2m² are detected with such a system during twilight conditions. The smallest detected LEO object with this system has a size of 0.32m x 0.32m x 0.26m. These measurements are compared to the developed link budget which allows an estimation of the performance of larger systems.

Effect of KOH concentration on LEO cycle life of IPV nickel-hydrogen flight cells. An update

NASA Technical Reports Server (NTRS)

Smithrick, John J.; Hall, Stephen W.

1991-01-01

An update of validation test results confirming the breakthrough in LEO cycle life of nickel-hydrogen cells containing 26 percent potassium hydroxide (KOH) electrolyte is presented. A breakthrough in the LEO cycle life of individual pressure vessel nickel-hydrogen cells is reported. The cycle life of boiler plate cells containing 26 percent KOH electrolyte was about 40,000 LEO cycles compared to 3500 cycles for cells containing 31 percent KOH.

Effect of KOH concentration on LEO cycle life of IPV nickel-hydrogen flight cells - An update

NASA Technical Reports Server (NTRS)

Smithrick, John J.; Hall, Stephen W.

1991-01-01

An update of validation test results confirming the breakthrough in LEO cycle life of nickel-hydrogen cells containing 26 percent potassium hydroxide (KOH) electrolyte is presented. A breakthrough in the LEO cycle life of individual pressure vessel nickel-hydrogen cells is reported. The cycle life of boiler plate cells containing 26 percent KOH electrolyte was about 40,000 LEO cycles compared to 3500 cycles for cells containing 31 percent KOH.

Effect of LEO cycling on 125 Ah advanced design IPV nickel-hydrogen flight cells - An update

NASA Technical Reports Server (NTRS)

Smithrick, John J.; Hall, Stephen W.

1991-01-01

An update of validation test results confirming the breakthrough in LEO cycle life of nickel-hydrogen cells containing 26 percent potassium hydroxide (KOH) electrolyte is presented. A breakthrough in the LEO cycle life of individual pressure vessel nickel-hydrogen cells is reported. The cycle life of boiler plate cells containing 26 percent KOH electrolyte was about 40,000 LEO cycles compared to 3500 cycles for cells containing 31 percent KOH.

Variable stars in the Leo A dwarf galaxy (DDO 69)

NASA Technical Reports Server (NTRS)

Hoessel, John G.; Saha, A.; Krist, John; Danielson, G. Edward

1994-01-01

Observations of the Leo A dwarf galaxy, obtained over the period from 1980 to 1991 are reported. Forty two separate Charge Coupled Devices (CCD) frames were searched for variable stars. A total of 14 suspected variables were found, 9 had sufficient coverage for period determination, and 5 had Cepheid light curves. Four of these stars fit well on a P-L relation and yield a distance modulus, after correction for Galactic foreground extinction, of m-M = 26.74. This corresponds to a distance of 2.2 Mpc, placing Leo A near the Local Group zero-velocity surface.

77 FR 50185 - LoCorr Fund Management, LLC and LoCorr Investment Trust; Notice of Application

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-20

... Fund Management, LLC and LoCorr Investment Trust; Notice of Application August 14, 2012. AGENCY.... Applicants: LoCorr Fund Management, LLC (``LFM'' or the ``Adviser'') and LoCorr Investment Trust (the ``Trust... Mary Kay Frech, Branch Chief, at (202) 551-6821 (Division of Investment Management, Office of...

Analysis of the effects of simulated synergistic LEO environment on solar panels

NASA Astrophysics Data System (ADS)

Allegri, G.; Corradi, S.; Marchetti, M.; Scaglione, S.

2007-02-01

The effects due to the LEO environment exposure of a solar array primary structure are here presented and discussed in detail. The synergistic damaging components featuring LEO environment are high vacuum, thermal cycling, neutral gas, ultraviolet (UV) radiation and cold plasma. The synergistic effects due to these environmental elements are simulated by "on ground" tests, performed in the Space Environment Simulator (SAS) at the University of Rome "La Sapienza"; numerical simulations are performed by the Space Environment Information System (SPENVIS), developed by the European Space Agency (ESA). A "safe life" design for a solar array primary structure is developed, taking into consideration the combined damaging action of the LEO environment components; therefore results from both numerical and experimental simulations are coupled within the framework of a standard finite element method (FEM) based design. The expected durability of the solar array primary structure, made of laminated sandwich composite, is evaluated assuming that the loads exerted on the structure itself are essentially dependent on thermo-elastic stresses. The optical degradation of surface materials and the stiffness and strength degradation of structural elements are taken into account to assess the global structural durability of the solar array under characteristic operative conditions in LEO environment.

Alfalfa discovery of the nearby gas-rich dwarf galaxy Leo P. IV. Distance measurement from LBT optical imaging

DOE Office of Scientific and Technical Information (OSTI.GOV)

McQuinn, Kristen B. W.; Skillman, Evan D.; Berg, Danielle

Leo P is a low-luminosity dwarf galaxy discovered through the blind H I Arecibo Legacy Fast ALFA survey. The H I and follow-up optical observations have shown that Leo P is a gas-rich dwarf galaxy with both active star formation and an underlying older population, as well as an extremely low oxygen abundance. Here, we measure the distance to Leo P by applying the tip of the red giant branch (TRGB) distance method to photometry of the resolved stellar population from new Large Binocular Telescope V and I band imaging. We measure a distance modulus of 26.19{sub −0.50}{sup +0.17} magmore » corresponding to a distance of 1.72{sub −0.40}{sup +0.14} Mpc. Although our photometry reaches 3 mag below the TRGB, the sparseness of the red giant branch yields higher uncertainties on the lower limit of the distance. Leo P is outside the Local Group with a distance and velocity consistent with the local Hubble flow. While located in a very low-density environment, Leo P lies within ∼0.5 Mpc of a loose association of dwarf galaxies which include NGC 3109, Antlia, Sextans A, and Sextans B, and 1.1 Mpc away from its next nearest neighbor, Leo A. Leo P is one of the lowest metallicity star-forming galaxies known in the nearby universe, comparable in metallicity to I Zw 18 and DDO 68, but with stellar characteristics similar to dwarf spheriodals (dSphs) in the Local Volume such as Carina, Sextans, and Leo II. Given its physical properties and isolation, Leo P may provide an evolutionary link between gas-rich dwarf irregular galaxies and dSphs that have fallen into a Local Group environment and been stripped of their gas.« less

Effect of KOH concentration on LEO cycle life of IPV nickel-hydrogen flight cell - Update II

NASA Technical Reports Server (NTRS)

Smithrick, John J.; Hall, Stephen W.

1992-01-01

An update of validation test results confirming the breakthrough in LEO cycle life of nickel-hydrogen cells containing 26 percent KOH electrolyte is presented. A breakthrough in the LEO cycle life of individual pressure vessel (IPV) nickel-hydrogen cells has been previously reported. The cycle life of boiler plate cells containing 26 percent potassium hydroxide (KOH) electrolyte was about 40,000 LEO cycles, compared to 3500 cycles for cells containing 31 percent KOH. The cycle regime was a stressful accelerated LEO, which consisted of a 27.5 min charge followed by a 17.5 min discharge (2X normal rate). The depth-of-discharge was 80 percent. Six 48-Ah Hughes recirculation design IPV nickel-hydrogen flight battery cells are being evaluated. Three of the cells contain 26 percent KOH (test cells), and three contain 31 percent KOH (control cells). They are undergoing real time LEO cycle life testing. The cycle regime is a 90-min LEO orbit consisting of a 54-min charge followed by a 36-min discharge. The depth-of-discharge is 80 percent. The cell temperature is maintained at 10 C. The three 31 percent KOH cells failed (cycles 3729, 4165, and 11355). One of the 26 percent KOH cells failed at cycle 15314. The other two 26 percent KOH cells were cycled for over 16,000 cycles during the continuing test.

Michigan Turns to Leo Goldberg

NASA Astrophysics Data System (ADS)

Lindner, Rudi P.

2006-12-01

The death of Heber D. Curtis at the beginning of 1942 emphasized the difficult circumstances facing Michigan's astronomy program. There were no funds to figure or mount the 98" pyrex blank; the 37" reflector labored under floodlights; and the war sapped the graduate program. For a number of years the staff argued over the best path for the future, goaded by the unwelcome intervention of the "amateurs" McMath and Hulbert. The administration brought in outside consultants, attempted to prevent the observatory staff from making separate arrangements, trawled in western waters without success, and took conflicting advice on the future direction of the science. In 1946 the university leadership had, as well, to consider the aftermath of the war: new possibilities in physics, new funding opportunities, a booming student population, and the encapsulation of the observatory within the medical campus. At this time, Leo Goldberg was on the McMath-Hulbert staff, had little to do with the Ann Arbor community, and was considered to be an outsider, beholden to astrophysical theory and his promoters at Harvard. Leo Goldberg's rise from relative obscurity, his transformation from assistant to leader, and the university leadership's assessment of the possibilities for the transformation of a midwest, urban, and traditional program form the topic of this paper, based upon the Michigan and Harvard archives as well as the memories of Goldberg's cohort.

DWARF IRREGULAR GALAXY LEO A: SUPRIME-CAM WIDE-FIELD STELLAR PHOTOMETRY

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stonkutė, Rima; Narbutis, Donatas; Vansevičius, Vladas

2014-10-01

We have surveyed a complete extent of Leo A—an apparently isolated gas-rich low-mass dwarf irregular galaxy in the Local Group. The B, V, and I passband CCD images (typical seeing ∼0.''8) were obtained with the Subaru Telescope equipped with the Suprime-Cam mosaic camera. The wide-field (20' × 24') photometry catalog of 38,856 objects (V ∼ 16-26 mag) is presented. This survey is also intended to serve as ''a finding chart'' for future imaging and spectroscopic observation programs of Leo A.

LEO P: HOW MANY METALS CAN A VERY LOW MASS, ISOLATED GALAXY RETAIN?

DOE Office of Scientific and Technical Information (OSTI.GOV)

McQuinn, Kristen B. W.; Skillman, Evan D.; Dolphin, Andrew

Leo P is a gas-rich dwarf galaxy with an extremely low gas-phase oxygen abundance (3% solar). The isolated nature of Leo P enables a quantitative measurement of metals lost solely due to star formation feedback. We present an inventory of the oxygen atoms in Leo P based on the gas-phase oxygen abundance measurement, the star formation history (SFH), and the chemical enrichment evolution derived from resolved stellar populations. The SFH also provides the total amount of oxygen produced. Overall, Leo P has retained 5% of its oxygen; 25% of the retained oxygen is in the stars while 75% is in the gas phase. Thismore » is considerably lower than the 20%–25% calculated for massive galaxies, supporting the trend for less efficient metal retention for lower-mass galaxies. The retention fraction is higher than that calculated for other alpha elements (Mg, Si, Ca) in dSph Milky Way satellites of similar stellar mass and metallicity. Accounting only for the oxygen retained in stars, our results are consistent with those derived for the alpha elements in dSph galaxies. Thus, under the assumption that the dSph galaxies lost the bulk of their gas mass through an environmental process such as tidal stripping, the estimates of retained metal fractions represent underestimates by roughly a factor of four. Because of its isolation, Leo P provides an important datum for the fraction of metals lost as a function of galaxy mass due to star formation.« less

Effect of KOH concentration on LEO cycle life of IPV nickel-hydrogen flight battery cells

NASA Technical Reports Server (NTRS)

Smithrick, John J.; Hall, Stephen W.

1990-01-01

A breakthrough in low earth orbit (LEO) cycle life of individual pressure vessel (IPV) nickel hydrogen battery cells was reported. The cycle life of boiler plate cells containing 26 percent potassium hydroxide (KOH) electrolyte was about 40,000 LEO cycles compared to 3500 cycles for cells containing 31 percent KOH. The effect of KOH concentration on cycle life was studied. The cycle regime was a stressful accelerated LEO, which consisted of a 27.5 min charge followed by a 17.5 min charge (2 x normal rate). The depth of discharge (DOD) was 80 percent. The cell temperature was maintained at 23 C. The next step is to validate these results using flight hardware and a real time LEO test. NASA Lewis has a contract with the Naval Weapons Support Center (NWSC), Crane, Indiana, to validate the boiler plate test results. Six 48 A-hr Hughes recirculation design IPV nickel-hydrogen flight battery cells are being evaluated. Three of the cells contain 26 percent KOH (test cells) and three contain 31 percent KOH (control cells). They are undergoing real time LEO cycle life testing. The cycle regime is a 90-min LEO orbit consisting of a 54-min charge followed by a 36-min discharge. The depth-of-discharge is 80 percent. The cell temperature is maintained at 10 C. The cells were cycled for over 8000 cycles in the continuing test. There were no failures for the cells containing 26 percent KOH. There was two failures, however, for the cells containing 31 percent KOH.

Effect of KOH concentration on LEO cycle life of IPV nickel-hydrogen flight battery cells

NASA Technical Reports Server (NTRS)

Smithrick, John J.; Hall, Stephen W.

1990-01-01

A breakthrough in the low-earth-orbit (LEO) cycle life of individual pressure vessel (IPV) nickel hydrogen battery cells is reported. The cycle life of boiler plate cells containing 26 percent potassium hydroxide (KOH) electrolyte was about 40,000 LEO cycles compared to 3500 cycles for cells containing 31 percent KOH. The effect of KOH concentration on cycle life was studied. The cycle regime was a stressful accelerated LEO, which consisted of a 27.5 min charge followed by a 17.5 min charge (2 x normal rate). The depth of discharge (DOD) was 80 percent. The cell temperature was maintained at 23 C. The next step is to validate these results using flight hardware and real time LEO test. NASA Lewis has a contract with the Naval Weapons Support Center (NWSC), Crane, Indiana to validate the boiler plate test results. Six 48 A-hr Hughes recirculation design IPV nickel-hydrogen flight battery cells are being evaluated. Three of the cells contain 26 percent KOH (test cells) and three contain 31 percent KOH (control cells). They are undergoing real time LEO cycle life testing. The cycle regime is a 90-min LEO orbit consisting of a 54-min charge followed by a 36-min discharge. The depth-of-discharge is 80 percent. The cell temperature is maintained at 10 C. The cells were cycled for over 8000 cycles in the continuing test. There were no failures for the cells containing 26 percent KOH. There were two failures, however, for the cells containing 31 percent KOH.

Deep neutral hydrogen observations of Leo T with the Westerbork Synthesis Radio Telescope

NASA Astrophysics Data System (ADS)

Adams, Elizabeth A. K.; Oosterloo, Tom A.

2018-04-01

Leo T is the lowest mass gas-rich galaxy currently known and studies of its gas content help us understand how such marginal galaxies survive and form stars. We present deep neutral hydrogen (H I) observations from the Westerbork Synthesis Radio Telescope in order to understand its H I distribution and potential for star formation. We find a larger H I line flux than the previously accepted value, resulting in a 50% larger H I mass of 4.1 × 105 M⊙. The additional H I flux is from low surface brightness emission that was previously missed; with careful masking this emission can be recovered even in shallower data. We perform a Gaussian spectral decomposition to find a cool neutral medium component (CNM) with a mass of 3.7 × 104 M⊙, or almost 10% of the total H I mass. Leo T has no H I emission extending from the main H I body, but there is evidence of interaction with the Milky Way circumgalactic medium in both a potential truncation of the H I body and the offset of the peak H I distribution from the optical center. The CNM component of Leo T is large when compared to other dwarf galaxies, even though Leo T is not currently forming stars and has a lower star formation efficiency than other gas-rich dwarf galaxies. However, the H I column density associated with the CNM component in Leo T is low. One possible explanation is the large CNM component is not related to star formation potential but rather a recent, transient phenomenon related to the interaction of Leo T with the Milky Way circumgalactic medium. The reduced datacube (FITS file) is only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/612/A26

Effect of KOH concentration on LEO cycle life of IPV nickel-hydrogen flight cells-update 2

NASA Technical Reports Server (NTRS)

Smithrick, John J.; Hall, Stephen W.

1991-01-01

An update of validation test results confirming the breakthrough in low earth orbit (LEO) cycle life of nickel-hydrogen cells containing 26 percent KOH electrolyte is presented. A breakthrough in the LEO cycle life of individual pressure vessel (IPV nickel-hydrogen cells has been previously reported. The cycle life of boiler plate cells containing 26 percent potassium hydroxide (KOH) electrolyte was about 40 000 LEO cycles compared to 3500 cycles for cells containing 31 percent KOH. This test was conducted at Hughes Aircraft Company under a NASA Lewis contract. The purpose was to investigate the effect of KOH concentration on cycle life. The cycle regime was a stressful accelerated LEO, which consisted of a 27.5 min charge followed by a 17.5 min discharge (2x normal rate). The depth of discharge (DOD) was 80 percent. The cell temperature was maintained at 23 C. The boiler plate test results are in the process of being validated using flight hardware and real time LEO test at the Naval Weapons Support Center (NWSC), Crane, Indiana under a NASA Lewis Contract. Six 48 Ah Hughes recirculation design IPV nickel-hydrogen flight battery cells are being evaluated. Three of the cells contain 26 percent KOH (test cells), and three contain 31 percent KOH (control cells). They are undergoing real time LEO cycle life testing. The cycle regime is a 90-min LEO orbit consisting of a 54-min charge followed by a 36-min discharge. The depth-of-discharge is 80 percent. The cell temperature is maintained at 10 C. The three 31 percent KOH cells failed (cycles 3729, 4165, and 11355). One of the 26 percent KOH cells failed at cycle 15314. The other two 26 percent KOH cells were cycled for over 16600 cycles during the continuing test.

The quick acquisition technique for laser communication between LEO and GEO

NASA Astrophysics Data System (ADS)

Zhang, Li-zhong; Zhang, Rui-qin; Li, Yong-hao; Meng, Li-xin; Li, Xiao-ming

2013-08-01

The sight-axis alignment can be accomplished by the quick acquisition operation between two laser communication terminals, which is the premise of establishing a free-space optical communication link. Especially for the laser communication links of LEO (Low Earth Orbit)-Ground and LEO-GEO (Geostationary Earth Orbit), since the earth would break the transmission of laser and break the communication as well, so the effective time for each communication is very shot (several minutes~ dozens of minutes), as a result the communication terminals have to capture each other to rebuild the laser communication link. In the paper, on the basis of the analysis of the traditional methods, it presents a new idea that using the long beacon light instead of the circular beacon light; thereby the original of two-dimensional raster spiral scanning is replaced by one-dimensional scanning. This method will reduce the setup time and decrease the failure probability of acquisition for the LEO-GEO laser communication link. Firstly, the analysis of the external constraint conditions in the acquisition phase has been presented in this paper. Furthermore, the acquisition algorithm models have been established. The optimization analysis for the parameters of the acquisition unit has been carried out, and the ground validation experiments of the acquisition strategy have also been performed. The experiments and analysis show that compared with traditional capturing methods, the method presented in this article can make the capturing time be shortened by about 40%, and the failure probability of capturing be reduced by about 30%. So, the method is significant for the LEO-GEO laser communication link.

A Generic Authentication LoA Derivation Model

NASA Astrophysics Data System (ADS)

Yao, Li; Zhang, Ning

One way of achieving a more fine-grained access control is to link an authentication level of assurance (LoA) derived from a requester’s authentication instance to the authorisation decision made to the requester. To realise this vision, there is a need for designing a LoA derivation model that supports the use and quantification of multiple LoA-effecting attributes, and analyse their composite effect on a given authentication instance. This paper reports the design of such a model, namely a generic LoA derivation model (GEA- LoADM). GEA-LoADM takes into account of multiple authentication attributes along with their relationships, abstracts the composite effect by the multiple attributes into a generic value, authentication LoA, and provides algorithms for the run-time derivation of LoA. The algorithms are tailored to reflect the relationships among the attributes involved in an authentication instance. The model has a number of valuable properties, including flexibility and extensibility; it can be applied to different application contexts and support easy addition of new attributes and removal of obsolete ones.

The Space Motion of Leo I: The Mass of the Milky Way's Dark Matter Halo

NASA Astrophysics Data System (ADS)

Boylan-Kolchin, Michael; Bullock, James S.; Sohn, Sangmo Tony; Besla, Gurtina; van der Marel, Roeland P.

2013-05-01

We combine our Hubble Space Telescope measurement of the proper motion of the Leo I dwarf spheroidal galaxy (presented in a companion paper) with the highest resolution numerical simulations of Galaxy-size dark matter halos in existence to constrain the mass of the Milky Way's dark matter halo (M vir, MW). Despite Leo I's large Galactocentric space velocity (200 km s-1) and distance (261 kpc), we show that it is extremely unlikely to be unbound if Galactic satellites are associated with dark matter substructure, as 99.9% of subhalos in the simulations are bound to their host. The observed position and velocity of Leo I strongly disfavor a low-mass Milky Way: if we assume that Leo I is the least bound of the Milky Way's classical satellites, then we find that M vir, MW > 1012 M ⊙ at 95% confidence for a variety of Bayesian priors on M vir, MW. In lower mass halos, it is vanishingly rare to find subhalos at 261 kpc moving as fast as Leo I. Should an additional classical satellite be found to be less bound than Leo I, this lower limit on M vir, MW would increase by 30%. Imposing a mass-weighted ΛCDM prior, we find a median Milky Way virial mass of M vir, MW = 1.6 × 1012 M ⊙, with a 90% confidence interval of [1.0-2.4] × 1012 M ⊙. We also confirm a strong correlation between subhalo infall time and orbital energy in the simulations and show that proper motions can aid significantly in interpreting the infall times and orbital histories of satellites.

High-voltage plasma interactions calculations using NASCAP/LEO

NASA Technical Reports Server (NTRS)

Mandell, M. J.; Katz, I.

1990-01-01

This paper reviews four previous simulations (two laboratory and two space-flight) of interactions of a high-voltage spacecraft with a plasma under low-earth orbit conditions, performed using a three-dimensional computer code NASCAP/LEO. Results show that NASCAP/LEO can perform meaningful simulations of high-voltage plasma interactions taking into account three-dimensional effects of geometry, spacecraft motion, and magnetic field. Two new calculations are presented: (1) for current collection by 1-mm pinholes in wires (showing that a pinhole in a wire can collect far more current than a similar pinhole in a flat plate); and (2) current collection by Charge-2 mother vehicle launched in December 1985. It is shown that the Charge-2 calculations predicted successfully ion collection at negative bias, the floating potential of a probe outside or inside the sheath under negative bias conditions, and magnetically limited electron collection under electron beam operation at high altitude.

The NUONCE engine for LEO networks

NASA Technical Reports Server (NTRS)

Lo, Martin W.; Estabrook, Polly

1995-01-01

Typical LEO networks use constellations which provide a uniform coverage. However, the demand for telecom service is dynamic and unevenly distributed around the world. We examine a more efficient and cost effective design by matching the satellite coverage with the cyclical demand for service around the world. Our approach is to use a non-uniform satellite distribution for the network. We have named this constellation design NUONCE for Non Uniform Optimal Network Communications Engine.

Sizing of "Mother Ship and Catcher" Concepts for LEO Small Debris Capture

NASA Technical Reports Server (NTRS)

Bacon, John B.

2009-01-01

Most Low Earth Orbit (LEO) debris lies in a limited number of inclination "bands" associated with launch latitudes, or with specific useful orbit inclinations (such as polar orbits). Such narrow inclination bands generally have a uniform spread over all possible Right Ascensions of Ascending Node (RAANs), creating a different orbit plane for nearly every piece of debris. This complicates concept of rendezvous and capture for debris removal. However, a low-orbiting satellite will always phase in RAAN faster than debris objects in higher orbits at the same inclination, potentially solving the problem. Such a base can serve as a single space-based launch facility (a "mother ship") that can tend and then send tiny individual catcher devices for each debris object, as the facility drifts into the same RAAN as the higher object. This presentation will highlight characteristic system requirements of such an architecture, including structural and navigation requirements, power, mass and dV budgets for both the mother ship and the mass-produced common catcher devices that would clean out selected inclination bands. The altitude and inclination regime over which a band is to be cleared, the size distribution of the debris, and the inclusion of additional mission priorities all affect the sizing of the system. It is demonstrated that major LEO hazardous debris reductions can be realized in each band with a single LEO launch of a single mother ship, with simple attached catchers of total mass less than typical commercial LEO launch capability.

Study of mobile satellite network based on GEO/LEO satellite constellation

NASA Astrophysics Data System (ADS)

Hu, Xiulin; Zeng, Yujiang; Wang, Ying; Wang, Xianhui

2005-11-01

Mobile satellite network with Inter Satellite Links (ISLs), which consists of non-geostationary satellites, has the characteristic of network topology's variability. This is a great challenge to the design and management of mobile satellite network. This paper analyzes the characteristics of mobile satellite network, takes multimedia Quality of Service (QoS) as the chief object and presents a reference model based on Geostationary Earth Orbit (GEO)/ Low Earth Orbit (LEO) satellite constellation which adapts to the design and management of mobile satellite network. In the reference model, LEO satellites constitute service subnet with responsibility for the access, transmission and switch of the multimedia services for mobile users, while GEO satellites constitute management subnet taking on the centralized management to service subnet. Additionally ground control centre realizes the whole monitoring and control via management subnet. Comparing with terrestrial network, the above reference model physically separates management subnet from service subnet, which not only enhances the advantage of centralized management but also overcomes the shortcoming of low reliability in terrestrial network. Routing of mobile satellite network based on GEO/LEO satellite constellation is also discussed in this paper.

Leo P: How Many Metals Can a Very Low Mass, Isolated Galaxy Retain?

NASA Astrophysics Data System (ADS)

McQuinn, Kristen B. W.; Skillman, Evan D.; Dolphin, Andrew; Cannon, John M.; Salzer, John J.; Rhode, Katherine L.; Adams, Elizabeth A. K.; Berg, Danielle; Giovanelli, Riccardo; Haynes, Martha P.

2015-12-01

Leo P is a gas-rich dwarf galaxy with an extremely low gas-phase oxygen abundance (3% solar). The isolated nature of Leo P enables a quantitative measurement of metals lost solely due to star formation feedback. We present an inventory of the oxygen atoms in Leo P based on the gas-phase oxygen abundance measurement, the star formation history (SFH), and the chemical enrichment evolution derived from resolved stellar populations. The SFH also provides the total amount of oxygen produced. Overall, Leo P has retained 5% of its oxygen; 25% of the retained oxygen is in the stars while 75% is in the gas phase. This is considerably lower than the 20%-25% calculated for massive galaxies, supporting the trend for less efficient metal retention for lower-mass galaxies. The retention fraction is higher than that calculated for other alpha elements (Mg, Si, Ca) in dSph Milky Way satellites of similar stellar mass and metallicity. Accounting only for the oxygen retained in stars, our results are consistent with those derived for the alpha elements in dSph galaxies. Thus, under the assumption that the dSph galaxies lost the bulk of their gas mass through an environmental process such as tidal stripping, the estimates of retained metal fractions represent underestimates by roughly a factor of four. Because of its isolation, Leo P provides an important datum for the fraction of metals lost as a function of galaxy mass due to star formation. Based on observations made with the NASA/ESA Hubble Space Telescope, obtained from the Data Archive at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-26555.

LEO to ground optical communications from a small satellite platform

NASA Astrophysics Data System (ADS)

Rose, T. S.; Janson, S. W.; LaLumondiere, S.; Werner, N.; Hinkley, D. H.; Rowen, D. W.; Fields, R. A.; Welle, R. P.

2015-03-01

A pair of 2.2 kg CubeSats using COTS hardware is being developed for a proof-of-principle optical communications demo from a 450-600 km LEO orbit to ground. The 10x10x15 cm platform incorporates a 25% wall-plug efficient 10-W Yb fiber transmitter emitting at 1.06 μm. Since there are no gimbals on board, the entire spacecraft is body-steered toward the ground station. The pointing accuracy of the LEO craft, which governs the data rate capability, is expected to be ~ 0.1-0.2 deg. Two optical ground stations, located at the Mt. Wilson observatory, have receiver apertures of 30 and 80 cm. Launch of the CubeSat pair is anticipated to be mid to late 2015.

The Leo I color-magnitude diagram

NASA Astrophysics Data System (ADS)

Reid, Neill; Mould, Jeremy

1991-04-01

The R-and I-band photometry of the Leo I dwarf galaxy is presented. A relatively narrow giant branch is found, Implying an abundance range of no more than Fe/H/= - 0.7 to - 1.3. This is in contrast to the results is found by Fox and Pritchet (1987) from BV CCD photometry. The distance modulus is estimated as (m - M) = 21.85 + or - 0.15, based on the luminosity of the tip of the red giant branch.

An Assessment of the Current LEO Debris Environment and the Need for Active Debris Removal

NASA Technical Reports Server (NTRS)

Liou, Jer-Chyi

2010-01-01

The anti-satellite test on the Fengun-1 C weather satellite in early 2007 and the collision between Iridium 33 and Cosmos 2251 in 2009 dramatically altered the landscape of the human-made orbital debris environment in the low Earth orbit (LEO). The two events generated approximately 5500 fragments large enough to be tracked by the U.S. Space Surveillance Network. Those fragments account for more than 60% increase to the debris population in LEO. However, even before the ASAT test, model analyses already indicated that the debris population (for those larger than 10 cm) in LEO had reached a point where the population would continue to increase, due to collisions among existing objects, even without any future launches. The conclusion implies that as satellites continue to be launched and unexpected breakup events continue to occur, commonly-adopted mitigation measures will not be able to stop the collision-driven population growth. To remediate the debris environment in LEO, active debris removal must be considered. This presentation will provide an updated assessment of the debris environment after the Iridium 33/Cosmos 2251 collision, an analysis of several future environment projections based on different scenarios, and a projection of collision activities in LEO in the near future. The need to use active debris removal to stabilize future debris environment will be demonstrated and the effectiveness of various active debris removal strategies will be quantified.

Global tracking and inventory of military hardware via LEO satellite: A system approach and likely scenario

NASA Technical Reports Server (NTRS)

Bell, David; Estabrook, Polly; Romer, Richard

1995-01-01

A system for global inventory control of electronically tagged military hardware is achievable using a LEO satellite constellation. An equipment Tag can communicate directly to the satellite with a power of 5 watts or less at a data rate of 2400 to 50,000 bps. As examples, two proposed commercial LEO systems, IRIDIUM and ORBCOMM, are both capable of providing global coverage but with dramatically different telecom capacities. Investigation of these two LEO systems as applied to the Tag scenario provides insight into satellite design trade-offs, constellation trade-offs and signal dynamics that effect the performance of a satellite-based global inventory control system.

Compensation of an attitude disturbance torque caused by magnetic substances in LEO satellites

NASA Astrophysics Data System (ADS)

Inamori, Takaya; Wang, Jihe; Saisutjarit, Phongsatorn; Ohsaki, Hiroyuki

This research considers an attitude disturbance torque caused by ferromagnetic substances in a LEO satellite. In most LEO satellite missions, a gravity gradient torque, solar pressure torque, aerodynamic torque, and magnetic dipole moment torque are considered for their attitude control systems, however, the effect of the ferromagnetic substances causing a disturbance torque in the geomagnetic field is not considered in previous satellite missions. The ferromagnetic substances such as iron cores of MTQs and a magnetic hysteresis damper for a passive attitude control system are used in various small satellites. These substances cause a disturbance torque which is almost the same magnitude of the dipole magnetic disturbance and the dominant disturbance in the worst cases. This research proposes a method to estimate and compensate for the effect of the ferromagnetic substances using an extended Kalman filter. From simulation results, the research concludes that the proposed method is useful and attractive for precise attitude control for LEO satellite missions.

Instability of the Present LEO Satellite Populations

NASA Technical Reports Server (NTRS)

Liou, Jer-Chyi; Johnson, Nicholas L.

2006-01-01

Several studies conducted during 1991-2001 demonstrated, with some assumed launch rates, the future unintended growth potential of the Earth satellite population, resulting from random, accidental collisions among resident space objects. In some low Earth orbit (LEO) altitude regimes where the number density of satellites is above a critical spatial density, the production rate of new breakup debris due to collisions would exceed the loss of objects due to orbital decay. A new study has been conducted in the Orbital Debris Program Office at the NASA Lyndon B. Johnson Space Center, using higher fidelity models to evaluate the current debris environment. The study assumed no satellites were launched after December 2005. A total of 150 Monte Carlo runs were carried out and analyzed. Each Monte Carlo run simulated the current debris environment and projected it 200 years into the future. The results indicate that the LEO debris environment has reached a point such that even if no further space launches were conducted, the Earth satellite population would remain relatively constant for only the next 50 years or so. Beyond that, the debris population would begin to increase noticeably, due to the production of collisional debris. Detailed analysis shows that this growth is primarily driven by high collision activities around 900 to 1000 km altitude - the region which has a very high concentration of debris at present. In reality, the satellite population growth in LEO will undoubtedly be worse than this study indicates, since spacecraft and their orbital stages will continue to be launched into space. Postmission disposal of vehicles (e.g., limiting postmission orbital lifetimes to less than 25 years) will help, but will be insufficient to constrain the Earth satellite population. To preserve better the near-Earth environment for future space activities, it might be necessary to remove existing large and massive objects from regions where high collision activities are

Arcing in Leo and Geo Simulated Environments: Comparative Analysis

NASA Technical Reports Server (NTRS)

Vayner, Boris V.; Ferguson, Dale C.; Galofaro, Joel TY.

2006-01-01

Comprehensive tests of two solar array samples in simulated Low Earth Orbit (LEO) and Geosynchronous Orbit (GEO) environments have demonstrated that the arc inception voltage was 2-3 times lower in the LEO plasma than in the GEO vacuum. Arc current pulse wave forms are also essentially different in these environments. Moreover, the wide variations of pulse forms do not allow introducing the definition of a "standard arc wave form" even in GEO conditions. Visual inspection of the samples after testing in a GEO environment revealed considerable damage on coverglass surfaces and interconnects. These harmful consequences can be explained by the discharge energy being one order of magnitude higher in vacuum than in background plasma. The tests also revealed a potential danger of powerful electrostatic discharges that could be initiated on the solar array surface of a satellite in GEO during the ignition of an arcjet thruster.

Handover aspects for a Low Earth Orbit (LEO) CDMA Land Mobile Satellite (LMS) system

NASA Technical Reports Server (NTRS)

Carter, P.; Beach, M. A.

1993-01-01

This paper addresses the problem of handoff in a land mobile satellite (LMS) system between adjacent satellites in a low earth orbit (LEO) constellation. In particular, emphasis is placed on the application of soft handoff in a direct sequence code division multiple access (DS-CDMA) LMS system. Soft handoff is explained in terms of terrestrial macroscopic diversity, in which signals transmitted via several independent fading paths are combined to enhance the link quality. This concept is then reconsidered in the context of a LEO LMS system. A two-state Markov channel model is used to simulate the effects of shadowing on the communications path from the mobile to each satellite during handoff. The results of the channel simulation form a platform for discussion regarding soft handoff, highlighting the potential merits of the scheme when applied in a LEO LMS environment.

Nickel metal hydride LEO cycle testing

NASA Technical Reports Server (NTRS)

Lowery, Eric

1995-01-01

The George C. Marshall Space Flight Center is working to characterize aerospace AB5 Nickel Metal Hydride (NiMH) cells. The cells are being evaluated in terms of storage, low earth orbit (LEO) cycling, and response to parametric testing (high rate charge and discharge, charge retention, pulse current ability, etc.). Cells manufactured by Eagle Picher are the subjects of the evaluation. There is speculation that NiMH cells may become direct replacements for current Nickel Cadmium cells in the near future.

LEDsats: LEO CubeSats with LEDs for Optical Tracking

NASA Astrophysics Data System (ADS)

Seitzer, P.; Cutler, J.; Piergentili, F.; Santoni, F.; Arena, L.; Cardona, T.; Cowardin, H.; Lee, C.; Sharma, S.

2016-09-01

We describe a project to launch 1U CubeSats equipped with Light Emitting Diodes (LEDs) into Low Earth Orbit (LEO) for optical tracking with ground-based telescopes. Active illumination on the satellites increases tremendously the number of passes where the LEO satellite is visible when the ground-based telescope is in darkness. The restriction that the satellite is in direct Sun is removed, and so tracking can take place all night long rather than just in twilight. The inspiration for this project came from the Japanese CubeSat FITSAT-1 that carried red and green high-powered LED arrays, and was clearly visible from the ground with small telescopes. There are two goals: 1) increase the accuracy and precision of LEO orbits by increasing the number and length of passes that satellite is visible, and 2) minimize the confusion between objects in the case of multiple CubeSats being launched at the same time. Technical issues to be discussed include the power level required for detection by small (20 - 40 cm) ground based telescopes, the optimum flash pattern for astrometry against star fields, and the timing of the flash pattern to millisecond or better accuracy and precision. We propose to deploy two such LEDsats simultaneously from the International Space Station: the first to be built at the University of Michigan, and the second to be built at Sapienza University Rome. One experiment is to see how we can distinguish these two CubeSats shortly after deployment solely from optical tracking, and so the CubeSats will have different flash patterns.

Automating Access Control Logics in Simple Type Theory with LEO-II

NASA Astrophysics Data System (ADS)

Benzmüller, Christoph

Garg and Abadi recently proved that prominent access control logics can be translated in a sound and complete way into modal logic S4. We have previously outlined how normal multimodal logics, including monomodal logics K and S4, can be embedded in simple type theory and we have demonstrated that the higher-order theorem prover LEO-II can automate reasoning in and about them. In this paper we combine these results and describe a sound (and complete) embedding of different access control logics in simple type theory. Employing this framework we show that the off the shelf theorem prover LEO-II can be applied to automate reasoning in and about prominent access control logics.

Establishing a Robotic, LEO-to-GEO Satellite Servicing Infrastructure as an Economic Foundation for Exploration

NASA Technical Reports Server (NTRS)

Horsham, Gary A. P.; Schmidt, George R.; Gilland, James H.

2010-01-01

The strategy for accomplishing civilian exploration goals and objectives is in the process of a fundamental shift towards a potential new approach called Flexible Path. This paper suggests that a government-industry or public-private partnership in the commercial development of low Earth orbit to geostationary orbit (LEO-to-GEO (LTG)) space, following or in parallel with the commercialization of Earth-to-LEO and International Space Station (ISS) operations, could serve as a necessary, logical step that can be incorporated into the flexible path approach. A LTG satellite-servicing infrastructure and architecture concept is discussed within this new strategic context. The concept consists of a space harbor that serves as a transport facility for a fleet of specialized, fully- or semi-autonomous robotic servicing spacecraft. The baseline, conceptual system architecture is composed of a space harbor equipped with specialized servicer spacecraft; a satellite command, communication, and control system; a parts station; a fuel station or depot; and a fuel/parts replenishment transport. The commercial servicer fleet would consist of several types of spacecraft, each designed with specialized robotic manipulation subsystems to provide services such as refueling, upgrade, repair, inspection, relocation, and removal. The space harbor is conceptualized as an ISS-type, octagonal truss structure equipped with radiation tolerant subsystems. This space harbor would be primarily capable of serving as an operational platform for various commercially owned and operated servicer spacecraft positioned and docked symmetrically on four of the eight sides. Several aspects of this concept are discussed, such as: system-level feasibility in terms of ISS-truss-type infrastructure and subsystems emplacement and maintenance between LEO and GEO; infrastructure components assembly in LEO, derived from ISS assembly experience, and transfer to various higher orbital locations; the evolving Earth

POSSIBLE CHROMOSPHERIC ACTIVITY CYCLES IN AD LEO

DOE Office of Scientific and Technical Information (OSTI.GOV)

Buccino, Andrea P.; Petrucci, Romina; Mauas, Pablo J. D.

2014-01-20

AD Leo (GJ 388) is an active dM3 flare star that has been extensively observed both in the quiescent and flaring states. Since this active star is near the fully convective boundary, studying its long-term chromospheric activity in detail could be an appreciable contribution to dynamo theory. Here, using the Lomb-Scargle periodogram, we analyze the Ca II K line-core fluxes derived from CASLEO spectra obtained between 2001 and 2013 and the V magnitude from the ASAS database between 2004 and 2010. From both of these totally independent time series, we obtain a possible activity cycle with a period of approximately seven yearsmore » and a less significant shorter cycle of approximately two years. A tentative interpretation is that a dynamo operating near the surface could be generating the longer cycle, while a second dynamo operating in the deep convection zone could be responsible for the shorter one. Based on the long duration of our observing program at CASLEO and the fact that we observe different spectral features simultaneously, we also analyze the relation between simultaneous measurements of the Na I index (R{sub D}{sup ′}), Hα, and Ca II K fluxes at different activity levels of AD Leo, including flares.« less

Comparison of two MAC protocols based on LEO satellite networks

NASA Astrophysics Data System (ADS)

Guan, Mingxiang; Wang, Ruichun

2009-12-01

With the development of LEO satellite communication, it is the basic requirement that various kinds of services will be provided. Considering that weak channel collision detection ability, long propagation delay and heavy load in LEO satellite communication system, a valid adaptive access control protocol APRMA is proposed. Different access probability functions for different services are obtained and appropriate access probabilities for voice and data users are updated slot by slot based on the estimation of the voice traffic and the channel status. Finally simulation results demonstrate that the performance of system is improved by the APRMA compared with the conventional PRMA, with an acceptable trade-off between QoS of voice and delay of data. Also the APRMA protocol will be suitable for HAPS (high altitude platform station) with the characters of weak channel collision detection ability, long propagation delay and heavy load.

LEO high voltage solar array arcing response model, continuation 5

NASA Technical Reports Server (NTRS)

Metz, Roger N.

1989-01-01

The modeling of the Debye Approximation electron sheaths in the edge and strip geometries was completed. Electrostatic potentials in these sheaths were compared to NASCAP/LEO solutions for similar geometries. Velocity fields, charge densities and particle fluxes to the biased surfaces were calculated for all cases. The major conclusion to be drawn from the comparisons of our Debye Approximation calculations with NASCAP-LEO output is that, where comparable biased structures can be defined and sufficient resolution obtained, these results are in general agreement. Numerical models for the Child-Langmuir, high-voltage electron sheaths in the edge and strip geometries were constructed. Electrostatic potentials were calculated for several cases in each of both geometries. Velocity fields and particle fluxes were calculated. The self-consistent solution process was carried through one cycle and output electrostatic potentials compared to NASCAP-type input potentials.

Pele Erupting on Lo

NASA Technical Reports Server (NTRS)

2001-01-01

This image of Jupiter's moon, lo, was taken by the Chandra X-Ray Observatory (CXO). Shown here is the most extreme example of the effect of tidal forces as Lo is being pulled by massive Jupiter on one side and by the outer moons Europa, Callisto, and Ganymede on the other. The opposing tidal forces alternately squeeze and stretch its interior, causing the solid surface to rise and fall by about 100 meters. The enormous amount of heat and pressure generated by the resulting friction creates colossal volcanoes and fractures on the surface of this moon.

A lunar transportation system

NASA Technical Reports Server (NTRS)

1986-01-01

Due to large amounts of oxygen required for space travel, a method of mining, transporting, and storing this oxygen in space would facilitate further space exploration. The following project deals specifically with the methods for transporting liquid oxygen from the lunar surface to the Lunar Orbit (LO) space station, and then to the Lower Earth Orbit (LEO) space station. Two vehicles were designed for operation between the LEO and LO space stations. The first of these vehicles is an aerobraked design vehicle. The Aerobrake Orbital Transfer Vehicle (OTV) is capable of transporting 5000 lbm of payload to LO while returning to LEO with 60,000 lbm of liquid oxygen, and thus meet mission requirements. The second vehicle can deliver 18,000 lbm of payload to LO and is capable of bringing 60,000 lbm of liquid oxygen back to LEO. A lunar landing vehicle was also designed for operation between LO and the established moon base. The use of an electromagnetic railgun as a method for launching the lunar lander was also investigated. The feasibility of the railgun is doubtful at this time. A system of spheres was also designed for proper storing and transporting of the liquid oxygen. The system assumes a safe means for transferring the liquid oxygen from tank to tank is operational. A sophisticated life support system was developed for both the OTV and the lunar lander. This system focuses on such factors as the vehicle environment, waste management, water requirements, food requirements, and oxygen requirements.

A new concept for high-cycle-life LEO: Rechargeable MnO2-hydrogen

NASA Technical Reports Server (NTRS)

Appleby, A. J.; Dhar, H. P.; Kim, Y. J.; Murphy, O. J.

1989-01-01

The nickel-hydrogen secondary battery system, developed in the early 1970s, has become the system of choice for geostationary earth orbit (GEO) applications. However, for low earth orbit (LEO) satellites with long expected lifetimes the nickel positive limits performance. This requires derating of the cell to achieve very long cycle life. A new system, rechargeable MnO2-Hydrogen, which does not require derating, is described here. For LEO applications, it promises to have longer cycle life, high rate capability, a higher effective energy density, and much lower self-discharge behavior than those of the nickel-hydrogen system.

Leo Szilard: Physics, Politics, and the Narrow Margin of Hope.

NASA Astrophysics Data System (ADS)

Lanouette, William

1998-04-01

Leo Szilard (1898-1964) was a creative physicist and biologist. But concern about how scientific discoveries might affect humanity also led him to seek political solutions to enlarge the benefits and limit the damage caused by his work. This disposition to save the world came to Szilard by the age of 10, when he read The Tragedy of Man, a Hungarian epic poem in which humanity faces extinction yet continues to survive by maintaining a narrow margin of hope. With this hope Szilard brought about improbable scientific and political feats (such as the nuclear chain reaction and the Moscow-Washington Hotline). This talk focuses on Szilard's many attempts in 1945 to prevent the atomic bombing of Japan. William Lanouette, a writer and public policy analyst, is the author of Genius in the Shadows: A Biography of Leo Szilard, The Man Behind the Bomb. (University of Chicago Press, 1994)

Recent Progress on the Second Generation CMORPH: LEO-IR Based Precipitation Estimates and Cloud Motion Vector

NASA Astrophysics Data System (ADS)

Xie, Pingping; Joyce, Robert; Wu, Shaorong

2015-04-01

As reported at the EGU General Assembly of 2014, a prototype system was developed for the second generation CMORPH to produce global analyses of 30-min precipitation on a 0.05olat/lon grid over the entire globe from pole to pole through integration of information from satellite observations as well as numerical model simulations. The second generation CMORPH is built upon the Kalman Filter based CMORPH algorithm of Joyce and Xie (2011). Inputs to the system include rainfall and snowfall rate retrievals from passive microwave (PMW) measurements aboard all available low earth orbit (LEO) satellites, precipitation estimates derived from infrared (IR) observations of geostationary (GEO) as well as LEO platforms, and precipitation simulations from numerical global models. Key to the success of the 2nd generation CMORPH, among a couple of other elements, are the development of a LEO-IR based precipitation estimation to fill in the polar gaps and objectively analyzed cloud motion vectors to capture the cloud movements of various spatial scales over the entire globe. In this presentation, we report our recent work on the refinement for these two important algorithm components. The prototype algorithm for the LEO IR precipitation estimation is refined to achieve improved quantitative accuracy and consistency with PMW retrievals. AVHRR IR TBB data from all LEO satellites are first remapped to a 0.05olat/lon grid over the entire globe and in a 30-min interval. Temporally and spatially co-located data pairs of the LEO TBB and inter-calibrated combined satellite PMW retrievals (MWCOMB) are then collected to construct tables. Precipitation at a grid box is derived from the TBB through matching the PDF tables for the TBB and the MWCOMB. This procedure is implemented for different season, latitude band and underlying surface types to account for the variations in the cloud - precipitation relationship. At the meantime, a sub-system is developed to construct analyzed fields of

Modeling the Energy Performance of LoRaWAN

PubMed Central

2017-01-01

LoRaWAN is a flagship Low-Power Wide Area Network (LPWAN) technology that has highly attracted much attention from the community in recent years. Many LoRaWAN end-devices, such as sensors or actuators, are expected not to be powered by the electricity grid; therefore, it is crucial to investigate the energy consumption of LoRaWAN. However, published works have only focused on this topic to a limited extent. In this paper, we present analytical models that allow the characterization of LoRaWAN end-device current consumption, lifetime and energy cost of data delivery. The models, which have been derived based on measurements on a currently prevalent LoRaWAN hardware platform, allow us to quantify the impact of relevant physical and Medium Access Control (MAC) layer LoRaWAN parameters and mechanisms, as well as Bit Error Rate (BER) and collisions, on energy performance. Among others, evaluation results show that an appropriately configured LoRaWAN end-device platform powered by a battery of 2400 mAh can achieve a 1-year lifetime while sending one message every 5 min, and an asymptotic theoretical lifetime of 6 years for infrequent communication. PMID:29035347

Modeling the Energy Performance of LoRaWAN.

PubMed

Casals, Lluís; Mir, Bernat; Vidal, Rafael; Gomez, Carles

2017-10-16

LoRaWAN is a flagship Low-Power Wide Area Network (LPWAN) technology that has highly attracted much attention from the community in recent years. Many LoRaWAN end-devices, such as sensors or actuators, are expected not to be powered by the electricity grid; therefore, it is crucial to investigate the energy consumption of LoRaWAN. However, published works have only focused on this topic to a limited extent. In this paper, we present analytical models that allow the characterization of LoRaWAN end-device current consumption, lifetime and energy cost of data delivery. The models, which have been derived based on measurements on a currently prevalent LoRaWAN hardware platform, allow us to quantify the impact of relevant physical and Medium Access Control (MAC) layer LoRaWAN parameters and mechanisms, as well as Bit Error Rate (BER) and collisions, on energy performance. Among others, evaluation results show that an appropriately configured LoRaWAN end-device platform powered by a battery of 2400 mAh can achieve a 1-year lifetime while sending one message every 5 min, and an asymptotic theoretical lifetime of 6 years for infrequent communication.

The Foreign Policy of Venezuela Toward El Salvador: 1979-1983

DTIC Science & Technology

1990-06-01

vista extra-regional, la "zona vital" es rica en materiales estrat~gicos, tales como el petr6leo, el hierro, y el aluminlo. Adem~s del petr6leo de...nivel de post-grado, en el Area de hidrocarburos para el periodo 1981 / 1982. Ofrecimiento de cooperaci6n en el campo de geologia de uranlo y materiales ...hombre, yo lo conocia, aparte de que era un homnbre muy preparado, muy inteligente , era un fan~tico. *Un fanatico religioso. Yo s6 porque lo digo

LEO Spacecraft Charging Guidelines

NASA Technical Reports Server (NTRS)

Hillard, G. B.; Ferguson, D. C.

2002-01-01

Over the past decade, Low Earth Orbiting (LEO) spacecraft have gradually required ever-increasing power levels. As a rule, this has been accomplished through the use of high voltage systems. Recent failures and anomalies on such spacecraft have been traced to various design practices and materials choices related to the high voltage solar arrays. NASA Glenn has studied these anomalies including plasma chamber testing on arrays similar to those that experienced difficulties on orbit. Many others in the community have been involved in a comprehensive effort to understand the problems and to develop practices to avoid them. The NASA Space Environments and Effects program, recognizing the timeliness of this effort, has commissioned and funded a design guidelines document intended to capture the current state of understanding. We present here an overview of this document, which is now nearing completion.

Human CD34(lo)CD133(lo) fetal liver cells support the expansion of human CD34(hi)CD133(hi) hematopoietic stem cells.

PubMed

Yong, Kylie Su Mei; Keng, Choong Tat; Tan, Shu Qi; Loh, Eva; Chang, Kenneth Te; Tan, Thiam Chye; Hong, Wanjin; Chen, Qingfeng

2016-09-01

We have recently discovered a unique CD34(lo)CD133(lo) cell population in the human fetal liver (FL) that gives rise to cells in the hepatic lineage. In this study, we further characterized the biological functions of FL CD34(lo)CD133(lo) cells. Our findings show that these CD34(lo)CD133(lo) cells express markers of both endodermal and mesodermal lineages and have the capability to differentiate into hepatocyte and mesenchymal lineage cells by ex vivo differentiation assays. Furthermore, we show that CD34(lo)CD133(lo) cells express growth factors that are important for human hematopoietic stem cell (HSC) expansion: stem cell factor (SCF), insulin-like growth factor 2 (IGF2), C-X-C motif chemokine 12 (CXCL12), and factors in the angiopoietin-like protein family. Co-culture of autologous FL HSCs and allogenic HSCs derived from cord blood with CD34(lo)CD133(lo) cells supports and expands both types of HSCs.These findings are not only essential for extending our understanding of the HSC niche during the development of embryonic and fetal hematopoiesis but will also potentially benefit adult stem cell transplantations in clinics because expanded HSCs demonstrate the same capacity as primary cells to reconstitute the human immune system and mediate long-term hematopoiesis in vivo. Together, CD34(lo)CD133(lo) cells not only serve as stem/progenitor cells for liver development but are also an essential component of the HSC niche in the human FL.

HERRO: A Science-Oriented Strategy for Crewed Missions Beyond LEO

NASA Technical Reports Server (NTRS)

Schmidt, George R.

2011-01-01

This paper presents an exploration strategy for human missions beyond Low Earth Orbit (LEO) and the Moon that combines the best features of human and robotic spaceflight. This "Human Exploration using Real-time Robotic Operations" (HERRO) strategy refrains from placing humans on the surfaces of the Moon and Mars in the near-term. Rather, it focuses on sending piloted spacecraft and crews into orbit around exploration targets of interest, such as Mars, and conducting astronaut exploration of the surfaces using telerobots and remotely controlled systems. By eliminating the significant communications delay with Earth due to the speed of light limit, teleoperation provides scientists real-time control of rovers and other sophisticated instruments, in effect giving them a "virtual presence" on planetary surfaces, and thus expanding the scientific return at these destinations. It also eliminates development of the numerous man-rated landers, ascent vehicles and surface systems that are required to land humans on planetary surfaces. The propulsive requirements to travel from LEO to many destinations with shallow gravity-wells in the inner solar system are quite similar. Thus, a single spacecraft design could perform a variety of missions, including orbit-based surface exploration of the Moon, Mars and Venus, and rendezvous with Near Earth Asteroids (NEAs), as well as Phobos and Deimos. Although HERRO bypasses many of the initial steps that have been historically associated with human space exploration, it opens the door to many new destinations that are candidates for future resource utilization and settlement. HERRO is a first step that takes humans to exciting destinations beyond LEO, while expanding the ability to conduct science within the inner solar system.

Tanker Argus: Re-supply for a LEO Cryogenic Propellant Depot

NASA Astrophysics Data System (ADS)

St. Germain, B.; Olds, J.; Kokan, T.; Marcus, L.; Miller, J.

The Argus reusable launch vehicle (RLV) concept is a single-stage-to-orbit conical, winged bodied vehicle powered by two liquid hydrogen/liquid oxygen supercharged ejector ramjets. The 3rd generation Argus launch vehicle utilizes advanced vehicle technologies along with a Maglev launch assist track. A tanker version of the Argus RLV is envisioned to provide an economical means of providing liquid fuel and oxidizer to an orbiting low-Earth orbit (LEO) propellant depot. This depot could then provide propellant to various spacecraft, including reusable orbital transfer vehicles used to ferry space solar power satellites to geo-stationary orbit. Two different tanker Argus configurations were analyzed. The first simply places additional propellant tanks inside the payload bay of an existing Argus reusable launch vehicle. The second concept is a modified Argus RLV in which the payload bay is removed and the vehicle propellant tanks are stretched to hold extra propellant. An iterative conceptual design process was used to design both Argus vehicles. This process involves various disciplines including aerodynamics, trajectory analysis, weights &structures, propulsion, operations, safety, and cost/economics. The payload bay version of tanker Argus, which has a gross mass of 256.3MT, is designed to deliver a 9.07MT payload to LEO. This payload includes propellant and the tank structure required to secure this propellant in the payload bay. The modified, pure tanker version of Argus has a gross mass of 218.6MT and is sized to deliver a full 9.07MT of propellant to LEO. The economic analysis performed for this study involved the calculation of many factors including the design/development and recurring costs of each vehicle. These results were used along with other economic assumptions to determine the "per kilogram" cost of delivering propellant to orbit. The results show that for a given flight rate the "per kilogram" cost is cheaper for the pure tanker version of Argus

Lo/Ld phase coexistence modulation induced by GM1.

PubMed

Puff, Nicolas; Watanabe, Chiho; Seigneuret, Michel; Angelova, Miglena I; Staneva, Galya

2014-08-01

Lipid rafts are assumed to undergo biologically important size-modulations from nanorafts to microrafts. Due to the complexity of cellular membranes, model systems become important tools, especially for the investigation of the factors affecting "raft-like" Lo domain size and the search for Lo nanodomains as precursors in Lo microdomain formation. Because lipid compositional change is the primary mechanism by which a cell can alter membrane phase behavior, we studied the effect of the ganglioside GM1 concentration on the Lo/Ld lateral phase separation in PC/SM/Chol/GM1 bilayers. GM1 above 1mol % abolishes the formation of the micrometer-scale Lo domains observed in GUVs. However, the apparently homogeneous phase observed in optical microscopy corresponds in fact, within a certain temperature range, to a Lo/Ld lateral phase separation taking place below the optical resolution. This nanoscale phase separation is revealed by fluorescence spectroscopy, including C12NBD-PC self-quenching and Laurdan GP measurements, and is supported by Gaussian spectral decomposition analysis. The temperature of formation of nanoscale Lo phase domains over an Ld phase is determined, and is shifted to higher values when the GM1 content increases. A "morphological" phase diagram could be made, and it displays three regions corresponding respectively to Lo/Ld micrometric phase separation, Lo/Ld nanometric phase separation, and a homogeneous Ld phase. We therefore show that a lipid only-based mechanism is able to control the existence and the sizes of phase-separated membrane domains. GM1 could act on the line tension, "arresting" domain growth and thereby stabilizing Lo nanodomains. Copyright © 2014 Elsevier B.V. All rights reserved.

Hubble Sees Galaxies Spiraling around Leo

NASA Image and Video Library

2014-04-18

Shown here is a spiral galaxy known as NGC 3455, which lies some 65 million light-years away from us in the constellation of Leo (the Lion). Galaxies are classified into different types according to their structure and appearance. This classification system is known as the Hubble Sequence, named after its creator Edwin Hubble. In this image released 14, April, 2014, NGC 3455 is known as a type SB galaxy — a barred spiral. Barred spiral galaxies account for approximately two thirds of all spirals. Galaxies of this type appear to have a bar of stars slicing through the bulge of stars at their center. The SB classification is further sub-divided by the appearance of a galaxy's pinwheeling spiral arms; SBa types have more tightly wound arms, whereas SBc types have looser ones. SBb types, such as NGC 3455, lie in between. NGC 3455 is part of a pair of galaxies — its partner, NGC 3454, lies out of frame. This cosmic duo belong to a group known as the NGC 3370 group, which is in turn one of the Leo II groups, a large collection of galaxies scattered some 30 million light-years to the right of the Virgo cluster. This image is from Hubble's Advanced Camera for Surveys. Credit: ESA/Hubble & NASA, Acknowledgement: Nick Rose NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

Mid-Infrared Observations of Possible Intergalactic Star Forming Regions in the Leo Ring

NASA Astrophysics Data System (ADS)

Giroux, Mark; Smith, B.; Struck, C.

2011-05-01

Within the Leo group of galaxies lies a gigantic loop of intergalactic gas known as the Leo Ring. Not clearly associated with any particular galaxy, its origin remains uncertain. It may be a primordial intergalactic cloud alternatively, it may be a collision ring, or have a tidal origin. Combining archival Spitzer images of this structure with published UV and optical data, we investigate the mid-infrared properties of possible knots of star formation in the ring. These sources are very faint in the mid-infrared compared to star forming regions in the tidal features of interacting galaxies. This suggests they are either deficient in dust, or they may not be associated with the ring.

Stent-assisted coiling of intracranial aneurysms using LEO stents: long-term follow-up in 153 patients.

PubMed

Sedat, Jacques; Chau, Yves; Gaudart, Jean; Sachet, Marina; Beuil, Stephanie; Lonjon, Michel

2018-02-01

Coiling associated with placement of a self-expandable intracranial stent has improved the treatment of intracranial wide-necked aneurysms. Little is known, however, about the durability of this treatment. The purpose of this report is to present our experience with the LEO stent and to evaluate the complications, effectiveness, and long-term results of this technique. We analyzed the records of 155 intracranial unruptured aneurysms that were treated by stent-assisted coiling with a LEO stent between 2008 and 2012. Procedural, early post-procedural, and delayed complications were recorded. Clinical and angiographic follow-up of patients was conducted over a period of at least 36 months. No procedural mortality was observed. One-month morbidity was observed in 14 out of 153 patients (9,15%). One hundred thirty-eight patients (with 140 aneurysms) had clinical and angiographic follow-up for more than 36 months. No aneurysm rupture was observed during follow-up. Four patients presented an intra-stent stenosis at 8 months, and 6 patients who had an early recurrence were retreated. Final results showed 85% complete occlusion, 13% neck remnants, and 2% stable incomplete occlusion. Stent-assisted coiling with the LEO stent is a safe and effective treatment for unruptured intracranial aneurysms. The long-term clinical outcomes with the LEO stent are excellent with a high rate of complete occlusion that is stable over time.

Ground-based simulation of LEO environment: Investigations of a select LDEF material: FEP Teflon (trademark)

NASA Technical Reports Server (NTRS)

Cross, Jon B.; Koontz, Steven L.

1993-01-01

The Long Duration Exposure Facility (LDEF) has produced a wealth of data on materials degradation in the low earth orbit (LEO) space environment and has conclusively shown that surface chemistry (as opposed to surface physics-sputtering) is the key to understanding and predicting the degradation of materials in the LEO environment. It is also clear that materials degradation and spacecraft contamination are closely linked and that the fundamental mechanisms responsible for this linking are in general not well understood especially in the area of synergistic effects. The study of the fundamental mechanisms underlying materials degradation in LEO is hampered by the fact that the degradation process itself is not observed during the actual exposure to the environment. Rather the aftermath of the degradation process is studied, i.e., the material that remains after exposure is observed and mechanisms are proposed to explain the observed results. The EOIM-3 flight experiment is an attempt to bring sophisticated diagnostic equipment into the space environment and monitor the degradation process in real time through the use of mass spectrometry. More experiments of this nature which would include surface sensitive diagnostics (Auger and photoelectron spectroscopes) are needed to truly unravel the basic chemical mechanisms involved in the materials degradation process. Since these in-space capabilities will most likely not be available in the near future, ground-based LEO simulation facilities employing sophisticated diagnostics are needed to further advance the basic understanding of the materials degradation mechanisms. The LEO simulation facility developed at Los Alamos National Laboratory has been used to investigate the atomic oxygen/vacuum ultraviolet (AO/VUV) enhanced degradation of FEP Teflon. The results show that photo-ejection of polymer fragments occur at elevated temperature (200 C), that VUV synergistic rare gas sputtering of polymer fragments occur even at

LEO-to-GEO low thrust chemical propulsion

NASA Technical Reports Server (NTRS)

Shoji, J. M.

1980-01-01

One approach being considered for transporting large space structures from low Earth orbit (LEO) to geosynchronous equatorial orbit (GEO) is the use of low thrust chemical propulsion systems. A variety of chemical rocket engine cycles evaluated for this application for oxygen/hydrogen and oxygen/hydrocarbon propellants (oxygen/methane and oxygen/RF-1) are discussed. These cycles include conventional propellant turbine drives, turboalternator/electric motor pump drive, and fuel cell/electric motor pump drive as well as pressure fed engines. Thrust chamber cooling analysis results are presented for regenerative/radiation and film/radiation cooling.

Advanced propulsion for LEO and GEO platforms

NASA Technical Reports Server (NTRS)

Sovey, James S.; Pidgeon, David J.

1990-01-01

Mission requirements and mass savings applicable to specific low earth orbit and geostationary earth orbit platforms using three highly developed propulsion systems are described. Advanced hypergolic bipropellant thrusters and hydrazine arcjets can provide about 11 percent additional instrument payload to 14,000 kg LEO platforms. By using electric propulsion on a 8,000 kg class GEO platform, mass savings in excess of 15 percent of the beginning-of-life platform mass are obtained. Effects of large, advanced technology solar arrays and antennas on platform propulsion requirements are also discussed.

Distribution of the GNSS-LEO occultation events over Egypt

NASA Astrophysics Data System (ADS)

Ghoniem, Ibrahim; Mousa, Ashraf El-Kutb; El-Fiky, Gamal

2017-06-01

The space-based GNSS RO technique is a promising tool for monitoring the Earth's atmosphere and ionosphere (Mousa et al., 2006). The current paper presents the distribution of the occultation events over Egypt using the operating LEO satellites and GNSS by its two operating systems. By the present research, Egypt could raise NWP Models efficiency by improving meteorological data quality. Twenty operating LEO missions (e.g. Argentinean SAC-C, European MetOp-A, German TerraSAR-X, Indian OceanSat-2, etc.) sent by different countries all over the world were used to derive the occultation events position through Egypt borders by receiving signal from the American global positioning system (GPS) and the Russian global navigation satellite system (GLONASS). Approximately 20,000 km Altitude satellites are transmitting enormous number of rays by the day to approximately 800 km satellites passing by the Earth atmosphere. Our mission is to derive all of these rays position (start and end) by calculating satellites position by the time, determine the rays in the occultation case and derive the atmosphere tangent point position for all occultating rays on the Earth surface (Occultation Events).

MEMS Reaction Control and Maneuvering for Picosat Beyond LEO

NASA Technical Reports Server (NTRS)

Alexeenko, Alina

2016-01-01

The MEMS Reaction Control and Maneuvering for Picosat Beyond LEO project will further develop a multi-functional small satellite technology for low-power attitude control, or orientation, of picosatellites beyond low Earth orbit (LEO). The Film-Evaporation MEMS Tunable Array (FEMTA) concept initially developed in 2013, is a thermal valving system which utilizes capillary forces in a microchannel to offset internal pressures in a bulk fluid. The local vapor pressure is increased by resistive film heating until it exceeds meniscus strength in a nozzle which induces vacuum boiling and provides a stagnation pressure equal to vapor pressure at that point which is used for propulsion. Interplanetary CubeSats can utilize FEMTA for high slew rate attitude corrections in addition to desaturating reaction wheels. The FEMTA in cooling mode can be used for thermal control during high-power communication events, which are likely to accompany the attitude correction. Current small satellite propulsion options are limited to orbit correction whereas picosatellites are lacking attitude control thrusters. The available attitude control systems are either quickly saturated reaction wheels or movable high drag surfaces with long response times.

The volatile OH Mainline Masers of R Leo

NASA Astrophysics Data System (ADS)

Lewis, B. M.

2004-12-01

R Leo was observed soon after the Arecibo upgrade, in mid-1999, when its principal 1665 & 1667 MHz masers respectively had intensities of 2.2 & 3.2 Jy: these had completely disappeared by mid-2002. The 1665 MHz maser has never exceeded 10 mJy since, while the 1667 has never exceeded 70 mJy. Moreover the initial decline of both, by factors of ≥ 25, occurred in 10 months. Though both masers recovered by a factor of ≥ 3 soon after, this was immediately followed by a sharp decline from which they have never rallied. The 1667 MHz maser declined from 1000 to 27 mJy over the first 9 months of 2001, and even more quickly, from 60 to 24 mJy, in 36 days through September 2004. This behaviour contrasts sharply with that of 1612 MHz masers of normal OH/IR stars, which commonly vary by a factor of three around the pulsation cycle, and which have on occasion been observed to disappear with an e-folding time of ˜ 1 yr (ApJ 548, L77). Nor is this difference simply the usual pulsational variation of OH mainlines, as those of R LMi only vary in intensity by a factor of three. We conclude that the mainline masers of R Leo are unusually volatile, and prone to an order of magnitude more variability than most such masers. The NIR colors of OH/IR stars follow a well-defined locus, whose entire extent is traversed ≤ 60 yr after the cessation of mass-loss. Lewis (BAAS 35, 1358) therefore argues that the rapid loss of 1612 MHz masers is set by changes in the maser pump following on changes in the reprocessing of stellar radiation by dust in the inner environs of its circumstellar shell. But the pumping of OH mainline masers is even more sensitive to the details of IR-line overlap than the 1612. The amplitude and brevity of changes in the OH mainline masers of R Leo therefore suggest that these are generated by small changes in IR line overlap.

Super NiCd Open-Circuit Storage and Low Earth Orbit (LEO) Life Test Evaluation

NASA Technical Reports Server (NTRS)

Baer, Jean Marie; Hwang, Warren C.; Ang, Valerie J.; Hayden, Jeff; Rao, Gopalakrishna; Day, John H. (Technical Monitor)

2002-01-01

This presentation discusses Air Force tests performed on super NiCd cells to measure their performance under conditions simulating Low Earth Orbit (LEO) conditions. Super NiCd cells offer potential advantages over existing NiCd cell designs including advanced cell design with improved separator material and electrode making processes, but handling and storage requires active charging. These tests conclude that the super NiCd cells support generic Air Force qualifications for conventional LEO missions (up to five years duration) and that handling and storage may not actually require active charging as previously assumed. Topics covered include: Test Plan, Initial Characterization Tests, Open-Circuit Storage Tests, and post storage capacities.

Comparison of currents predicted by NASCAP/LEO model simulations with elementary Langmuir-type bare probe models for an insulated cable containing a single pinhole

NASA Technical Reports Server (NTRS)

Galofaro, Joel T.

1990-01-01

The behavior of a defect in the insulation of a short biased section of cable in a Low Earth Orbit (LEO) space environment was examined. Such studies are of the utmost importance for large space power systems where great quantities of cabling will be deployed. An insulated probe containing a pinhole was placed into a hypothetical high speed LEO plasma. The NASA Charging Analyzer Program (NASCAP/LEO) was used to explore sheath growth about the probe as a function of applied voltage and to predict I-V behavior. A set of independent current calculations using Langmuir's formulations for concentric spheres and coaxial cylinders were also performed. The case of concentric spheres was here extended to include the case of concentric hemispheres. Several simple Langmuir-type models were then constructed to bracket the current collected by the cable. The space-charge sheath radius and impact parameters were used to determine the proper current regime. I-V curves were plotted for the models and comparisons were made with NASCAP/LEO results. Finally, NASCAP/LEO potential contours and surface cell potential plots were examined to explain interesting features in the NASCAP/LEO I-V curve.

Degradation of Silicon Carbide Reflective Surfaces in the LEO Environment

NASA Astrophysics Data System (ADS)

Mileti, Sandro; Coluzzi, Plinio; Marchetti, Mario

2009-01-01

Space mirrors in Low Earth Orbit (LEO) encounter a degradation problem caused by the impact of atomic oxygen (ATOX) in the space environment. This paper presents an experiment of the atomic oxygen impact degradation and UV synergic effects on ground simulation. The experiment was carried out in a dedicated ATOX simulation vacuum chamber. As target materials, a polished CVD Beta-silicon carbide (SiC) coating was investigated. The selection of silicon carbide is due to its high potential candidate as a mirror layer substrate material for its good reflectance at UV wavelengths and excellent thermal diffusivity. It has highly desirable mechanical and thermal properties and can achieve an excellent surface finish. The deposition of the coatings were on carbon-based material substrate; i.e., silicon impregnated carbon fiber composite (C/SiC). Mechanical and thermal properties of the coatings such as hardness and Coefficient of Thermal Expansion (CTE) were achieved. Several atomic oxygen impact angles were studied tilting the target samples respect to the flux direction. The various impact angles permitted to analyze the different erosion rates and typologies which the mirrors would encounter in LEO environment. The degradation was analyzed in various aspects. Macroscopic mass loss per unit area, surface roughness and morphology change were basically analyzed. The exposed surfaces of the materials were observed through a Scanning Electron Microscope (SEM). Secondly, optical diagnostic of the surfaces were performed in order to investigate their variation in optical properties as the evaluation of reflectance degradation. The presence of micro-cracks caused by shrinkage, grinding, polishing or thermal cycling and the porosity in the coatings, could have led to the undercutting phenomenon. Observation of uprising of undercutting was also conducted. Remarks are given regarding capabilities in short-term mission exposures to the LEO environment of this coating.

Beller Lecture: The Roots of Leo Szilard and his Interdisciplinarity

NASA Astrophysics Data System (ADS)

Marx, George

1998-04-01

A Central European among the whites was said about Leo Szilard who originated from a polycultural family. In the early 20th century he grew up in Hungary, at the crossroads of history, where political regimes, national borders, ideological doctrines, ``final truths'' changed in a dizzying cavalcade. Instead of conservative dogmatism this social environment required critical thinking in order to survive. World War I was the school of Theodore von Kármán, John von Neumann, Eugene P. Wigner and Leo Szilard; each of them learned trespassing political and disciplinary boundaries without inhibition. Their sensitivity for trends had been utilized by the United States when war efforts and high tech required orientation under new horizons. Szilard's interest ranged from statistical physics through information theory to biological evolution, from life phenomena through hot atoms to nuclear strategy. His intellectual adventures might look crazy jumps for specialists. But now, looking back to the political and technological history of the 20th century one can see than it was a consequent progress of a future-sensitive mind.

Ixion: A Wet-Lab Habitat Platform for Leo and the Deep Space Gateway

NASA Astrophysics Data System (ADS)

Wald, S. I.; Cummins, C. K.; Manber, J.

2018-02-01

Cislunar and LEO habitats derived from launch vehicle upper stages are technically feasible and continues development toward flight. Present station specifications, configurations, and concepts for scientific, exploration, and commercial utilization.

ILLUMA-T (Integrated LCRD LEO User Modem and Amplifier Terminal) Payload

NASA Technical Reports Server (NTRS)

Seas, Antonios; Gonnsen, Zachary; Yarnall, Timothy

2018-01-01

Presentation on ILLUMA-T (Integrated LCRD LEO User Modem and Amplifier Terminal) Payload at the Japanese Experiment Module (JEM) External Payload Interface Coordination Meeting on May 9, 2018 at the Japan Aerospace Exploration Agency (JAXA) in Tsukuba, Japan. Meeting to discuss details of installing payload on JEM.

Estimating Solar Proton Flux at LEO From a Geomagnetic Cutoff Model

DTIC Science & Technology

2015-07-14

simple shadow cones (using nomenclature from Stormer theory of particle motion in a dipole magnetic field [6]), that result from particles trajectories...basic Stormer theory [7]. However, in LEO the changes would be small relative to uncertainties in the model and therefore unnecessary. If the model were

Controlling the Growth of Future LEO Debris Populations with Active Debris Removal

NASA Technical Reports Server (NTRS)

Liou, J.-C.; Johnson, N. L.; Hill, N. M.

2008-01-01

Active debris removal (ADR) was suggested as a potential means to remediate the low Earth orbit (LEO) debris environment as early as the 1980s. The reasons ADR has not become practical are due to its technical difficulties and the high cost associated with the approach. However, as the LEO debris populations continue to increase, ADR may be the only option to preserve the near-Earth environment for future generations. An initial study was completed in 2007 to demonstrate that a simple ADR target selection criterion could be developed to reduce the future debris population growth. The present paper summarizes a comprehensive study based on more realistic simulation scenarios, including fragments generated from the 2007 Fengyun-1C event, mitigation measures, and other target selection options. The simulations were based on the NASA long-term orbital debris projection model, LEGEND. A scenario, where at the end of mission lifetimes, spacecraft and upper stages were moved to 25-year decay orbits, was adopted as the baseline environment for comparison. Different annual removal rates and different ADR target selection criteria were tested, and the resulting 200-year future environment projections were compared with the baseline scenario. Results of this parametric study indicate that (1) an effective removal strategy can be developed based on the mass and collision probability of each object as the selection criterion, and (2) the LEO environment can be stabilized in the next 200 years with an ADR removal rate of five objects per year.

Complete mitochondrial genome of a Asian lion (Panthera leo goojratensis).

PubMed

Li, Yu-Fei; Wang, Qiang; Zhao, Jian-ning

2016-01-01

The entire mitochondrial genome of this Asian lion (Panthera leo goojratensis) was 17,183 bp in length, gene composition and arrangement conformed to other lions, which contained the typical structure of 22 tRNAs, 2 rRNAs, 13 protein-coding genes and a non-coding region. The characteristic of the mitochondrial genome was analyzed in detail.

Neoconservatism and Leo Strauss: The Place of a Liberal Education

ERIC Educational Resources Information Center

York, J. G.

2008-01-01

This paper is concerned with the work of Leo Strauss, specifically his two essays on liberal education. Strauss is often claimed to be a founding thinker of neoconservatism and while much scholarship has been produced analyzing his work, very little discusses his essays on liberal education and how these fit within his larger project. This essay…

Project LEO Studies of Science Learning Environments and Outcomes, 1968-1981.

ERIC Educational Resources Information Center

Matthews, Charles; And Others

Presented is a summary of the 1977-80 Project LEO studies, which focused on science teaching strategies and learning outcomes for disruptive elementary school children and on more refined application of the "student-structured learning in science" (SSLS) teacher behavioral pattern in secondary school science classrooms. Included within…

The Sublime Corpse in Gertrudis Gomez de Avellaneda's Women's Journal "Album Cubano de lo Bueno y lo Bello" (1860)

ERIC Educational Resources Information Center

LaGreca, Nancy

2009-01-01

This article examines Gertrudis Gomez de Avellaneda's choice to include articles depicting the advanced decay of cadavers, which are simultaneously horrible and awesome, in her women's periodical "Album Cubano de lo Bueno y lo Bello". Background on Avellaneda's biography, women's print culture, and theories of the sublime provide a frame for the…

On the feasibility of phase only PPP for kinematic LEO orbits

NASA Astrophysics Data System (ADS)

Wallat, Christoph; Schön, Steffen

2016-04-01

Low Earth Orbiters (LEO) are satellites in altitudes up to 1000 kilometers. From the sensor data collected on board the Earth's gravity field can be recovered. Over the last 15 years several satellite missions were brought into space and the orbit determination improved over the years. To process the sensor data, precise positioning and timing of the satellite is mandatory. There are two approaches for precise orbit determination (POD) of LEO satellites. Kinematic orbits are based on GNSS observations and star camera data measured on board of the LEO. With a Precise Point Positioning (PPP) known from the terrestrial case, using ionospheric-free linear combinations P3 and L3 three-dimensional coordinates of the LEO can be estimated for every observation epoch. To counteract the challenges in kinematic orbit determination our approach is based on a technique called GNSS receiver clock modeling (RCM). Here the frequency stability of an external oscillator is used to model the behavior of the GNSS receiver clock with piecewise linear polynomials instead of estimating epoch-wise the receiver clock time offset as an unknown parameter. When using RCM the observation geometry is stabilized and the orbit coordinates and the receiver clock error can be estimated with a better precision. The satellites of the Gravity Recovery And Climate Experiment (GRACE) mission are equipped with Ultra Stable quartz Oscillators (USO). The USO frequency stability is used to correct the GRACE GPS receiver clock. Therefore, receiver clock modeling is feasible for polynomials with a length up to 60 seconds, leading to improved mean PDOP values of 30 % and smaller formal mean standard deviations of the coordinates between 6 and 33 %. We developed a new approach for GRACE orbits using kinematic PPP with clock modeling and tested our approach with simulated and real GPS data. The idea to use only carrier phase observations in the final processing and no code measurements leads to a reduced number

Effect of LEO cycling on 125 Ah advanced design IPV nickel-hydrogen battery cells

NASA Technical Reports Server (NTRS)

Smithrick, John J.; Hall, Stephen W.

1990-01-01

An advanced 125 Ah individual pressure vessel (IPV) nickel-hydrogen cell was designed. The primary function of the advanced cell, is to store and deliver energy for long term, low earth-orbit (LEO) spacecraft missions. The new features of this design are: (1) use of 26 percent rather than 31 percent potassium hydroxide (KOH) electrolyte, (2) use of a patented catalyzed wall wick, (3) use of serrated edge separators to facilitate gaseous oxygen and hydrogen flow within the cell, while still maintaining physical contact with the wall wick for electrolyte management, and (4) use of a floating rather than a fixed stack (state-of-the-art) to accommodate nickel electrode expansion. Six 125 Ah flight cells based on this design were fabricated by Eagle-Picher. Three of the cells contain all of the advanced features (test cells) and three are the same as the test cells except they don't have catalyst on the wall wick (control cells). All six cells are in the process of being evaluated in a LEO cycle life test. The cells have accumulated about 4700 LEO cycles (60 percent DOD 10 C). There have been no cell failures, the catalyzed wall wick cells however, are performing better.

Effect of LEO cycling on 125 Ah advanced design IPV nickel-hydrogen battery cells

NASA Technical Reports Server (NTRS)

Smithrick, John J.; Hall, Stephen W.

1990-01-01

An advanced 125 Ah individual pressure vessel (IPV) nickel-hydrogen cell was designed. The primary function of the advanced cell is to store and deliver energy for long-term, low earth-orbit (LEO) spacecraft missions. The new features of this design are: (1) use of 26 percent rather than 31 percent potassium hydroxide (KOH) electrolyte, (2) use of a patented catalyzed wall wick, (3) use of serrated-edge separators to facilitate gaseous oxygen and hydrogen flow within the cell, while still maintaining physical contact with the wall wick for electrolyte management, and (4) use of a floating rather than a fixed stack (state-of-the-art) to accommodate nickel electrode expansion. Six 125-Ah flight cells based on this design were fabricated by Eagle-Picher. Three of the cells contain all of the advanced features (test cells) and three are the same as the test cells except they don't have catalyst on the wall wick (control cells). All six cells are in the process of being evaluated in a LEO cycle life test. The cells have accumulated about 4700 LEO cycles (60 percent DOD 10 C). There have been no cell failures; the catalyzed wall wick cells, however, are performing better.

Satellite Telemetry and Command using Big LEO Mobile Telecommunications Systems

NASA Technical Reports Server (NTRS)

Huegel, Fred

1998-01-01

Various issues associated with satellite telemetry and command using Big LEO mobile telecommunications systems are presented in viewgraph form. Specific topics include: 1) Commercial Satellite system overviews: Globalstar, ICO, and Iridium; 2) System capabilities and cost reduction; 3) Satellite constellations and contact limitations; 4) Capabilities of Globalstar, ICO and Iridium with emphasis on Globalstar; and 5) Flight transceiver issues and security.

Human Exploration Beyond LEO by the End of the Decade: Designs for Long-Duration "Gateway" Habitats

NASA Technical Reports Server (NTRS)

Thronson, Harley; Barr, Jonathan; Budinoff, Jason; Dorsey, John; Gold, Michael; Kutter, Bernard; Lester, Daniel; Moe, Rud; Sauls, Bobby; Spampinato, Phillip;

Multivariate Patterns in the Human Object-Processing Pathway Reveal a Shift from Retinotopic to Shape Curvature Representations in Lateral Occipital Areas, LO-1 and LO-2.

PubMed

Vernon, Richard J W; Gouws, André D; Lawrence, Samuel J D; Wade, Alex R; Morland, Antony B

2016-05-25

Representations in early visual areas are organized on the basis of retinotopy, but this organizational principle appears to lose prominence in the extrastriate cortex. Nevertheless, an extrastriate region, such as the shape-selective lateral occipital cortex (LO), must still base its activation on the responses from earlier retinotopic visual areas, implying that a transition from retinotopic to "functional" organizations should exist. We hypothesized that such a transition may lie in LO-1 or LO-2, two visual areas lying between retinotopically defined V3d and functionally defined LO. Using a rapid event-related fMRI paradigm, we measured neural similarity in 12 human participants between pairs of stimuli differing along dimensions of shape exemplar and shape complexity within both retinotopically and functionally defined visual areas. These neural similarity measures were then compared with low-level and more abstract (curvature-based) measures of stimulus similarity. We found that low-level, but not abstract, stimulus measures predicted V1-V3 responses, whereas the converse was true for LO, a double dissociation. Critically, abstract stimulus measures were most predictive of responses within LO-2, akin to LO, whereas both low-level and abstract measures were predictive for responses within LO-1, perhaps indicating a transitional point between those two organizational principles. Similar transitions to abstract representations were not observed in the more ventral stream passing through V4 and VO-1/2. The transition we observed in LO-1 and LO-2 demonstrates that a more "abstracted" representation, typically considered the preserve of "category-selective" extrastriate cortex, can nevertheless emerge in retinotopic regions. Visual areas are typically identified either through retinotopy (e.g., V1-V3) or from functional selectivity [e.g., shape-selective lateral occipital complex (LOC)]. We combined these approaches to explore the nature of shape representations

The Application of GIM in Precise Orbit Determination for LEO Satellites with Single-frequency GPS Measurements

NASA Astrophysics Data System (ADS)

Peng, D. J.; Wu, B.

2012-01-01

With the availability of precise GPS ephemeris and clock solution, the ionospheric range delay is left as the dominant error sources in the post-processing of space-borne GPS data from single-frequency receivers. Thus, the removal of ionospheric effects is a major prerequisite for an improved orbit reconstruction of LEO satellites equipped with low cost single-frequency GPS receivers. In this paper, the use of Global Ionospheric Maps (GIM) in kinematic and dynamic orbit determination for LEO satellites with single-frequency GPS measurements is discussed first,and then, estimating the scale factor of ionosphere to remove the ionospheric effects in C/A code pseudo-range measurements in both kinematic and adynamia orbit defemination approaches is addressed. As it is known the ionospheric path delay of space-borne GPS signals is strongly dependent on the orbit altitudes of LEO satellites, we selected real space-borne GPS data from CHAMP, GRACE, TerraSAR-X and SAC-C satellites with altitudes between 300 km and 800 km as sample data in this paper. It is demonstrated that the approach of eliminating ionospheric effects in space-borne C/A code pseudo-range by estimating the scale factor of ionosphere is highly effective. Employing this approach, the accuracy of both kinematic and dynamic orbits can be improved notably. Among those five LEO satellites, CHAMP with the lowest orbit altitude has the most remarkable orbit accuracy improvements, which are 55.6% and 47.6% for kinematic and dynamic approaches, respectively. SAC-C with the highest orbit altitude has the least orbit accuracy improvements accordingly, which are 47.8% and 38.2%, respectively.

The Application of GIM in Precise Orbit Determination for LEO Satellites with Single-Frequency GPS Measurements

NASA Astrophysics Data System (ADS)

Peng, Dong-ju; Wu, Bin

2012-10-01

With the precise GPS ephemeris and clock error available, the iono- spheric delay is left as the dominant error source in the single-frequency GPS data. Thus, the removal of ionospheric effects is a ma jor prerequisite for an improved orbit reconstruction of LEO satellites based on the single-frequency GPS data. In this paper, the use of Global Ionospheric Maps (GIM) in kine- matic and dynamic orbit determinations for LEO satellites with single-frequency GPS pseudorange measurements is discussed first, and then, estimating the iono- spheric scale factor to remove the ionospheric effects from the C/A-code pseu- dorange measurements for both kinematic and dynamic orbit determinations is addressed. As it is known that the ionospheric delay of space-borne GPS sig- nals is strongly dependent on the orbit altitudes of LEO satellites, we select the real C/A-code pseudorange measurement data of the CHAMP, GRACE, TerraSAR-X and SAC-C satellites with altitudes between 300 km and 800 km as sample data in this paper. It is demonstrated that the approach to eliminating ionospheric effects in C/A-code pseudorange measurements by estimating the ionospheric scale factor is highly effective. Employing this approach, the accu- racy of both kinematic and dynamic orbits can be improved notably. Among those five LEO satellites, CHAMP with the lowest orbit altitude has the most remarkable improvements in orbit accuracy, which are 55.6% and 47.6% for kine- matic and dynamic orbits, respectively. SAC-C with the highest orbit altitude has the least improvements in orbit accuracy accordingly, which are 47.8% and 38.2%, respectively.

LEOPACK The integrated services communications system based on LEO satellites

NASA Astrophysics Data System (ADS)

Negoda, A.; Bunin, S.; Bushuev, E.; Dranovsky, V.

LEOPACK is yet another LEO satellite project which provides global integrated services for 'business' communications. It utilizes packet rather then circuit switching in both terrestrial and satellite chains as well as cellular approach for frequencies use. Original multiple access protocols and decentralized network control make it possible to organize regionally or logically independent and world-wide networks. Relatively small number of satellites (28) provides virtually global network coverage.

Multivariate Patterns in the Human Object-Processing Pathway Reveal a Shift from Retinotopic to Shape Curvature Representations in Lateral Occipital Areas, LO-1 and LO-2

PubMed Central

Vernon, Richard J. W.; Gouws, André D.; Lawrence, Samuel J. D.; Wade, Alex R.

2016-01-01

Representations in early visual areas are organized on the basis of retinotopy, but this organizational principle appears to lose prominence in the extrastriate cortex. Nevertheless, an extrastriate region, such as the shape-selective lateral occipital cortex (LO), must still base its activation on the responses from earlier retinotopic visual areas, implying that a transition from retinotopic to “functional” organizations should exist. We hypothesized that such a transition may lie in LO-1 or LO-2, two visual areas lying between retinotopically defined V3d and functionally defined LO. Using a rapid event-related fMRI paradigm, we measured neural similarity in 12 human participants between pairs of stimuli differing along dimensions of shape exemplar and shape complexity within both retinotopically and functionally defined visual areas. These neural similarity measures were then compared with low-level and more abstract (curvature-based) measures of stimulus similarity. We found that low-level, but not abstract, stimulus measures predicted V1–V3 responses, whereas the converse was true for LO, a double dissociation. Critically, abstract stimulus measures were most predictive of responses within LO-2, akin to LO, whereas both low-level and abstract measures were predictive for responses within LO-1, perhaps indicating a transitional point between those two organizational principles. Similar transitions to abstract representations were not observed in the more ventral stream passing through V4 and VO-1/2. The transition we observed in LO-1 and LO-2 demonstrates that a more “abstracted” representation, typically considered the preserve of “category-selective” extrastriate cortex, can nevertheless emerge in retinotopic regions. SIGNIFICANCE STATEMENT Visual areas are typically identified either through retinotopy (e.g., V1–V3) or from functional selectivity [e.g., shape-selective lateral occipital complex (LOC)]. We combined these approaches to explore

Serendipitous Discovery of RR Lyrae Stars in the Leo V Ultra-faint Galaxy

NASA Astrophysics Data System (ADS)

Medina, Gustavo E.; Muñoz, Ricardo R.; Vivas, A. Katherina; Förster, Francisco; Carlin, Jeffrey L.; Martinez, Jorge; Galbany, Lluis; González-Gaitán, Santiago; Hamuy, Mario; de Jaeger, Thomas; Maureira, Juan Carlos; San Martín, Jaime

2017-08-01

During the analysis of RR Lyrae stars (RRLs) discovered in the High Cadence Transient Survey (HiTS) taken with the Dark Energy Camera at the 4 m telescope at Cerro Tololo Inter-American Observatory, we found a group of three very distant, fundamental mode pulsator RR Lyrae (type ab). The location of these stars agrees with them belonging to the Leo V ultra-faint satellite galaxy, for which no variable stars have been reported to date. The heliocentric distance derived for Leo V based on these stars is 173 ± 5 kpc. The pulsational properties (amplitudes and periods) of these stars locate them within the locus of the Oosterhoff II group, similar to most other ultra-faint galaxies with known RRLs. This serendipitous discovery shows that distant RRLs may be used to search for unknown faint stellar systems in the outskirts of the Milky Way.

Demonstration of Uncued Optical Surveillance of LEO

NASA Astrophysics Data System (ADS)

Zimmer, P.; Ackermann, M.; McGraw, J.

2014-09-01

J.T. McGraw and Associates, LLC, in collaboration with the University of New Mexico (UNM), has built and is operating two proof-of-concept wide-field imaging systems to test novel techniques for uncued surveillance of LEO. The imaging systems are built from off-the-shelf optics and detectors resulting in a 350mm aperture and a 6 square degree field of view. For streak detection, field of view is of critical importance because the maximum exposure time on the object is limited by its crossing time and measurements of apparent angular motion are better constrained with longer streaks. The current match of the detector to the optical system is optimized for detection of objects at altitudes above 450km, which for a circular orbit, corresponds to apparent motions of approximately 1 deg./sec. Using our GPU-accelerated detection scheme, the proof-of-concept systems have detected objects fainter than V=12.3, which approximately corresponds to a 24 cm object at 1000 km altitude at better than 6 sigma significance, from sites near and within Albuquerque, NM. This work demonstrates scalable optical systems designed for near real time detection of fast moving objects, which can be then handed off to other instruments capable of tracking and characterizing them. The two proof-of-concept systems, separated by ~30km, work together by taking simultaneous images of the same orbital volume to constrain the orbits of detected objects using parallax measurements. These detections are followed-up by photometric observations taken at UNM to independently assess the objects and the quality of the derived orbits. We believe this demonstrates the potential of small telescope arrays for detecting and cataloguing heretofore unknown LEO objects.

Sizing of "Mother Ship and Catcher" Missions for LEO Small Debris and for GEO Large Object Capture

NASA Technical Reports Server (NTRS)

Bacon, John B.

2009-01-01

Most LEO debris lies in a limited number of inclination "bands" associated with specific useful orbits. Objects in such narrow inclination bands have all possible Right Ascensions of Ascending Node (RAANs), creating a different orbit plane for nearly every piece of debris. However, a low-orbiting satellite will always phase in RAAN faster than debris objects in higher orbits at the same inclination, potentially solving the problem. Such a low-orbiting base can serve as a "mother ship" that can tend and then send small, disposable common individual catcher/deboost devices--one for each debris object--as the facility drifts into the same RAAN as each higher object. The dV necessary to catch highly-eccentric orbit debris in the center of the band alternatively allows the capture of less-eccentric debris in a wider inclination range around the center. It is demonstrated that most LEO hazardous debris can be removed from orbit in three years, using a single LEO launch of one mother ship--with its onboard magazine of freeflying low-tech catchers--into each of ten identified bands, with second or potentially third launches into only the three highest-inclination bands. The nearly 1000 objects near the geostationary orbit present special challenges in mass, maneuverability, and ultimate disposal options, leading to a dramatically different architecture and technology suite than the LEO solution. It is shown that the entire population of near-GEO derelict objects can be gathered and tethered together within a 3 year period for future scrap-yard operations using achievable technologies and only two earth launches.

Space environmental effects on spacecraft: LEO materials selection guide, part 2

NASA Astrophysics Data System (ADS)

Silverman, Edward M.

1995-08-01

This document provides performance properties on major spacecraft materials and subsystems that have been exposed to the low-Earth orbit (LEO) space environment. Spacecraft materials include metals, polymers, composites, white and black paints, thermal-control blankets, adhesives, and lubricants. Spacecraft subsystems include optical components, solar cells, and electronics. Information has been compiled from LEO short-term spaceflight experiments (e.g., space shuttle) and from retrieved satellites of longer mission durations (e.g., Long Duration Exposure Facility). Major space environment effects include atomic oxygen (AO), ultraviolet radiation, micrometeoroids and debris, contamination, and particle radiation. The main objective of this document is to provide a decision tool to designers for designing spacecraft and structures. This document identifies the space environments that will affect the performance of materials and components, e.g., thermal-optical property changes of paints due to UV exposures, AO-induced surface erosion of composites, dimensional changes due to thermal cycling, vacuum-induced moisture outgassing, and surface optical changes due to AO/UV exposures. Where appropriate, relationships between the space environment and the attendant material/system effects are identified. Part 2 covers thermal control systems, power systems, optical components, electronic systems, and applications.

Space environmental effects on spacecraft: LEO materials selection guide, part 2

NASA Technical Reports Server (NTRS)

Silverman, Edward M.

1995-01-01

This document provides performance properties on major spacecraft materials and subsystems that have been exposed to the low-Earth orbit (LEO) space environment. Spacecraft materials include metals, polymers, composites, white and black paints, thermal-control blankets, adhesives, and lubricants. Spacecraft subsystems include optical components, solar cells, and electronics. Information has been compiled from LEO short-term spaceflight experiments (e.g., space shuttle) and from retrieved satellites of longer mission durations (e.g., Long Duration Exposure Facility). Major space environment effects include atomic oxygen (AO), ultraviolet radiation, micrometeoroids and debris, contamination, and particle radiation. The main objective of this document is to provide a decision tool to designers for designing spacecraft and structures. This document identifies the space environments that will affect the performance of materials and components, e.g., thermal-optical property changes of paints due to UV exposures, AO-induced surface erosion of composites, dimensional changes due to thermal cycling, vacuum-induced moisture outgassing, and surface optical changes due to AO/UV exposures. Where appropriate, relationships between the space environment and the attendant material/system effects are identified. Part 2 covers thermal control systems, power systems, optical components, electronic systems, and applications.

Chemistry and Kinematics of the Late-forming Dwarf Irregular Galaxies Leo A, Aquarius, and Sagittarius DIG

NASA Astrophysics Data System (ADS)

Kirby, Evan N.; Rizzi, Luca; Held, Enrico V.; Cohen, Judith G.; Cole, Andrew A.; Manning, Ellen M.; Skillman, Evan D.; Weisz, Daniel R.

2017-01-01

We present Keck/DEIMOS spectroscopy of individual stars in the relatively isolated Local Group dwarf galaxies Leo A, Aquarius, and the Sagittarius dwarf irregular galaxy. The three galaxies—but especially Leo A and Aquarius—share in common delayed star formation histories (SFHs) relative to many other isolated dwarf galaxies. The stars in all three galaxies are supported by dispersion. We found no evidence of stellar velocity structure, even for Aquarius, which has rotating H I gas. The velocity dispersions indicate that all three galaxies are dark-matter-dominated, with dark-to-baryonic mass ratios ranging from {4.4}-0.8+1.0 (SagDIG) to {9.6}-1.8+2.5 (Aquarius). Leo A and SagDIG have lower stellar metallicities than Aquarius, and they also have higher gas fractions, both of which would be expected if Aquarius were further along in its chemical evolution. The metallicity distribution of Leo A is inconsistent with a closed or leaky box model of chemical evolution, suggesting that the galaxy was pre-enriched or acquired external gas during star formation. The metallicities of stars increased steadily for all three galaxies, but possibly at different rates. The [α/Fe] ratios at a given [Fe/H] are lower than that of the Sculptor dwarf spheroidal galaxy, which indicates more extended SFHs than Sculptor, consistent with photometrically derived SFHs. Overall, the bulk kinematic and chemical properties for the late-forming dwarf galaxies do not diverge significantly from those of less delayed dwarf galaxies, including dwarf spheroidal galaxies. The data presented herein were obtained at the W. M. Keck Observatory, which is operated as a scientific partnership among the California Institute of Technology, the University of California, and the National Aeronautics and Space Administration. The Observatory was made possible by the generous financial support of the W. M. Keck Foundation.

The LEO Archipelago: A system of earth-rings for communications, mass-transport to space, solar power, and control of global warming

NASA Astrophysics Data System (ADS)

Meulenberg, Andrew; Karthik Balaji, P. S.

2011-06-01

Man's quest to get into space is hindered by major problems (e.g., system-development and capital costs, expense of putting mass into orbit, trapped-radiation belts, and environmental impact of a large increase in rocket launches). A multi-purpose low-earth-orbit system of rings circling the earth - the "LEO ARCHIPELAGO TM" - is proposed as a means of solving or bypassing many of them. A fiber-optic ring about the earth would be an initial testing and developmental stage for the Ring Systems, while providing cash-flow through a LEO-based, high-band-width, world-wide communication system. A low-earth-orbit-based space-elevator system, "Sling-on-a-Ring TM", is proposed as the crucial developmental stage of the LEO Archipelago. Being a LEO-based heavy-mass lifter, rather than earth- or GEO-based, it is much less massive and therefore less costly than other proposed space-elevators. With the advent of lower-cost, higher-mass transport to orbit, the options for further space development (e.g., space solar power, radiation, and space-debris dampers, sun shades, and permanent LEO habitation) are greatly expanded. This paper provides an update of the Sling-on-a-Ring concept in terms of new materials, potential applications, and trade-offs associated with an earlier model. The impact of Colossal Carbon Tubes, CCT, a new material with high tensile strength, extremely-low density, and other favorable properties, and other new technologies (e.g., solar-powered lasers, power beaming to near-space and earth, and thermal-control systems) on the development of associated LEO-Ring systems is also explored. The material's effect on the timeline for the system development indicates the feasibility of near-term implementation of the system (possibly within the decade). The Sling-on-a-Ring can provide a less-expensive, environment-friendly mode of access to space. This would pave the way (via eventual operation at >1000 t per day by 2050) for large scale development of space

A Parametric Study on Using Active Debris Removal for LEO Environment Remediation

NASA Technical Reports Server (NTRS)

2010-01-01

Recent analyses on the instability of the orbital debris population in the low Earth orbit (LEO) region and the collision between Iridium 33 and Cosmos 2251 have reignited the interest in using active debris removal (ADR) to remediate the environment. There are; however, monumental technical, resource, operational, legal, and political challenges in making economically viable ADR a reality. Before a consensus on the need for ADR can be reached, a careful analysis of its effectiveness must be conducted. The goal is to demonstrate the need and feasibility of using ADR to better preserve the future environment and to guide its implementation to maximize the benefit-to-cost ratio. This paper describes a new sensitivity study on using ADR to stabilize the future LEO debris environment. The NASA long-term orbital debris evolutionary model, LEGEND, is used to quantify the effects of several key parameters, including target selection criteria/constraints and the starting epoch of ADR implementation. Additional analyses on potential ADR targets among the currently existing satellites and the benefits of collision avoidance maneuvers are also included.

Ambient noise tomography of Lo'ihi

NASA Astrophysics Data System (ADS)

McClement, K.; Thurber, C. H.; Teel, A.; Caplan-Auerbach, J.

2012-12-01

Lo'ihi seamount, the youngest volcano in the Hawaiian-Emperor chain, lies approximately 30 km south of Hawai'i Island with its summit still approximately 1 km below sea level. Lo'ihi offers a unique opportunity to study the early formation of a hotspot volcano and can provide insight into the deep internal structure of the other volcanoes that make up the Hawaiian Islands. This study uses Ambient Noise Tomography (ANT) to create a 3D tomographic image of Lo'ihi's S-wave velocity structure from ocean bottom seismometer (OBS) data. ANT has been used in many subaerial studies but has seen very few applications to OBS data. This study uses continuous data recorded in 2010 to 2011 from 12 short-period OBS instruments deployed on and around Lo'ihi. With the farthest distance between stations being just over 30 km, the stations provide a fairly dense coverage mainly for the northern half of the volcano. Following the approach of Masterlark et al. [2010], we computed vertical-vertical and vertical-radial cross-correlations using 97 days of continuous data from the 12 stations to produce the ambient noise Green's functions. From these, dispersion curves were produced over a frequency range from .04 Hz to 0.65 Hz . After a quality control analysis, checkerboard tests were used to determine a suitable cell size for the 2D group velocity inversions. The final step is the inversion of the group velocity dispersion curves to create a 3D Vs model. The 3D Vs image produced through this method does not provide clear evidence of a shallow magma chamber; however, when compared to a previous P-wave velocity (Vp) model [Caplan-Auerbach, 2001], a high Vp/Vs ratio is evident especially at depths from 1 km to 5 km, indicating the presence of highly fractured rock.

Contrast Invariant Interest Point Detection by Zero-Norm LoG Filter.

PubMed

Zhenwei Miao; Xudong Jiang; Kim-Hui Yap

2016-01-01

The Laplacian of Gaussian (LoG) filter is widely used in interest point detection. However, low-contrast image structures, though stable and significant, are often submerged by the high-contrast ones in the response image of the LoG filter, and hence are difficult to be detected. To solve this problem, we derive a generalized LoG filter, and propose a zero-norm LoG filter. The response of the zero-norm LoG filter is proportional to the weighted number of bright/dark pixels in a local region, which makes this filter be invariant to the image contrast. Based on the zero-norm LoG filter, we develop an interest point detector to extract local structures from images. Compared with the contrast dependent detectors, such as the popular scale invariant feature transform detector, the proposed detector is robust to illumination changes and abrupt variations of images. Experiments on benchmark databases demonstrate the superior performance of the proposed zero-norm LoG detector in terms of the repeatability and matching score of the detected points as well as the image recognition rate under different conditions.

Improved Orbit Determination of LEO CubeSats: Project LEDsat

NASA Astrophysics Data System (ADS)

Cutler, J.; Seitzer, P.; Lee, C. H.; Washabaugh, P.; Sharma, S.; Gitten, R.; Piergentili, F.; Santoni, F.; Cardona, T.; Cialone, G.; Frezza, L.; Gianfermo, A.; Marzioli, P.; Masillo, S.; Pellegrino, A.; Schildknecht, T.; Bedard, D.; Cowardin, H.

Project LEDsat is an international project (USA, Italy, and Canada) designed to improve the identification and orbit determination of CubeSats in low Earth orbit (LEO). The goal is to fly CubeSats with multiple methods of measuring positions on the same spacecraft: GPS, optical tracking, satellite laser ranging (SLR), and radio tracking. These satellites will be equipped with light emitting diodes (LEDs) for optical tracking while the satellite is in Earth shadow. It will be possible to compare the orbits determined from different methods to examine the systematic and random errors associated with each method. Furthermore, if each LEDsat has a different flash pattern, then it will be possible to distinguish closely spaced satellites shortly after deployment. The Sapienza University of Rome 3U CubeSat URSA MAIOR with LEDs and retro-reflectors was launched in June 2017 and is working on orbit. Sapienza has designed a 1U CubeSat follow-on mission dedicated to LED tracking, which was selected for possible launch in 2018 in the European Space Agency's (ESA) 'Fly Your Satellite' program. The University of Michigan is designing a 3U version with LEDs, GPS receiver, SLR, and radio tracking. The Royal Military College of Canada (RMC) is leading a Canadian effort for a LEDsat mission as well. All three organizations have a program of testing LEDs for space use to predict the effects of the LEO space environment.

Time Serial Analysis of the Induced LEO Environment within the ISS 6A

NASA Technical Reports Server (NTRS)

Wilson, John W.; Nealy, John E.; Tomov, B. T.; Cucinotta, Francis A.; Badavi, Frank F.; DeAngelis, Giovanni; Atwell, William; Leutke, N.

2006-01-01

Anisotropies in the low Earth orbit (LEO) radiation environment were found to influence the thermoluminescence detectors (TLD) dose within the (International Space Station) ISS 7A Service Module. Subsequently, anisotropic environmental models with improved dynamic time extrapolation have been developed including westward and northern drifts using AP8 Min & Max as estimates of the historic spatial distribution of trapped protons in the 1965 and 1970 era, respectively. In addition, a directional dependent geomagnetic cutoff model was derived for geomagnetic field configurations from the 1945 to 2020 time frame. A dynamic neutron albedo model based on our atmospheric radiation studies has likewise been required to explain LEO neutron measurements. The simultaneous measurements of dose and dose rate using four Liulin instruments at various locations in the US LAB and Node 1 has experimentally demonstrated anisotropic effects in ISS 6A and are used herein to evaluate the adequacy of these revised environmental models.

The Komplast Experiment: Space Environmental Effects after 12 Years in LEO (and Counting)

NASA Technical Reports Server (NTRS)

Shaevich, Sergei K.; Aleksandrov, Nicholai G.; Shumov, Andrei E.; Novikov, L. S.; Alred, John A.; Shindo, David J.; Kravchenko, Michael; Golden, Johnny L.

2014-01-01

The Komplast materials experiment was designed by the Khrunichev Space Center, together with other Russian scientific institutes, and has been carried out by Mission Control Moscow since 1998. The purpose is to study the effect of the low earth orbit (LEO) environment on exposed samples of various spacecraft materials. The Komplast experiment began with the launch of the first International Space Station (ISS) module on November 20, 1998. Two of eight experiment panels were retrieved during Russian extravehicular activity in February 2011 after 12 years of LEO exposure, and were subsequently returned to Earth by Space Shuttle "Discovery" on the STS-133/ULF-5 mission. The retrieved panels contained an experiment to detect micrometeoroid and orbital debris (MMOD) impacts, radiation sensors, a temperature sensor, several pieces of electrical cable, both carbon composite and adhesive-bonded samples, and many samples made from elastomeric and fluoroplastic materials. Our investigation is complete and a summary of the results obtained from this uniquely long-duration exposure experiment will be presented.

Design and Fabrication of DebriSat - A Representative LEO Satellite for Improvements to Standard Satellite Breakup Models

NASA Technical Reports Server (NTRS)

Clark, S.; Dietrich, A.; Fitz-Coy, N.; Weremeyer, M.; Liou, J.-C.

2012-01-01

This paper discusses the design and fabrication of DebriSat, a 50 kg satellite developed to be representative of a modern low Earth orbit satellite in terms of its components, materials used, and fabrication procedures. DebriSat will be the target of a future hypervelocity impact experiment to determine the physical characteristics of debris generated after an on-orbit collision of a modern LEO satellite. The major ground-based satellite impact experiment used by DoD and NASA in their development of satellite breakup models was SOCIT, conducted in 1992. The target used for that experiment was a Navy transit satellite (40 cm, 35 kg) fabricated in the 1960's. Modern satellites are very different in materials and construction techniques than those built 40 years ago. Therefore, there is a need to conduct a similar experiment using a modern target satellite to improve the fidelity of the satellite breakup models. To ensure that DebriSat is truly representative of typical LEO missions, a comprehensive study of historical LEO satellite designs and missions within the past 15 years for satellites ranging from 1 kg to 5000 kg was conducted. This study identified modern trends in hardware, material, and construction practices utilized in recent LEO missions. Although DebriSat is an engineering model, specific attention is placed on the quality, type, and quantity of the materials used in its fabrication to ensure the integrity of the outcome. With the exception of software, all other aspects of the satellite s design, fabrication, and assembly integration and testing will be as rigorous as that of an actual flight vehicle. For example, to simulate survivability of launch loads, DebriSat will be subjected to a vibration test. As well, the satellite will undergo thermal vacuum tests to verify that the components and overall systems meet typical environmental standards. Proper assembly and integration techniques will involve comprehensive joint analysis, including the precise

Phylogeographic Patterns in Africa and High Resolution Delineation of Genetic Clades in the Lion (Panthera leo)

NASA Astrophysics Data System (ADS)

Bertola, L. D.; Jongbloed, H.; van der Gaag, K. J.; de Knijff, P.; Yamaguchi, N.; Hooghiemstra, H.; Bauer, H.; Henschel, P.; White, P. A.; Driscoll, C. A.; Tende, T.; Ottosson, U.; Saidu, Y.; Vrieling, K.; de Iongh, H. H.

2016-08-01

Comparative phylogeography of African savannah mammals shows a congruent pattern in which populations in West/Central Africa are distinct from populations in East/Southern Africa. However, for the lion, all African populations are currently classified as a single subspecies (Panthera leo leo), while the only remaining population in Asia is considered to be distinct (Panthera leo persica). This distinction is disputed both by morphological and genetic data. In this study we introduce the lion as a model for African phylogeography. Analyses of mtDNA sequences reveal six supported clades and a strongly supported ancestral dichotomy with northern populations (West Africa, Central Africa, North Africa/Asia) on one branch, and southern populations (North East Africa, East/Southern Africa and South West Africa) on the other. We review taxonomies and phylogenies of other large savannah mammals, illustrating that similar clades are found in other species. The described phylogeographic pattern is considered in relation to large scale environmental changes in Africa over the past 300,000 years, attributable to climate. Refugial areas, predicted by climate envelope models, further confirm the observed pattern. We support the revision of current lion taxonomy, as recognition of a northern and a southern subspecies is more parsimonious with the evolutionary history of the lion.

Phylogeographic Patterns in Africa and High Resolution Delineation of Genetic Clades in the Lion (Panthera leo).

PubMed

Bertola, L D; Jongbloed, H; van der Gaag, K J; de Knijff, P; Yamaguchi, N; Hooghiemstra, H; Bauer, H; Henschel, P; White, P A; Driscoll, C A; Tende, T; Ottosson, U; Saidu, Y; Vrieling, K; de Iongh, H H

2016-08-04

Comparative phylogeography of African savannah mammals shows a congruent pattern in which populations in West/Central Africa are distinct from populations in East/Southern Africa. However, for the lion, all African populations are currently classified as a single subspecies (Panthera leo leo), while the only remaining population in Asia is considered to be distinct (Panthera leo persica). This distinction is disputed both by morphological and genetic data. In this study we introduce the lion as a model for African phylogeography. Analyses of mtDNA sequences reveal six supported clades and a strongly supported ancestral dichotomy with northern populations (West Africa, Central Africa, North Africa/Asia) on one branch, and southern populations (North East Africa, East/Southern Africa and South West Africa) on the other. We review taxonomies and phylogenies of other large savannah mammals, illustrating that similar clades are found in other species. The described phylogeographic pattern is considered in relation to large scale environmental changes in Africa over the past 300,000 years, attributable to climate. Refugial areas, predicted by climate envelope models, further confirm the observed pattern. We support the revision of current lion taxonomy, as recognition of a northern and a southern subspecies is more parsimonious with the evolutionary history of the lion.

Phylogeographic Patterns in Africa and High Resolution Delineation of Genetic Clades in the Lion (Panthera leo)

PubMed Central

Bertola, L. D.; Jongbloed, H.; van der Gaag, K. J.; de Knijff, P.; Yamaguchi, N.; Hooghiemstra, H.; Bauer, H.; Henschel, P.; White, P. A.; Driscoll, C. A.; Tende, T.; Ottosson, U.; Saidu, Y.; Vrieling, K.; de Iongh, H. H.

2016-01-01

Comparative phylogeography of African savannah mammals shows a congruent pattern in which populations in West/Central Africa are distinct from populations in East/Southern Africa. However, for the lion, all African populations are currently classified as a single subspecies (Panthera leo leo), while the only remaining population in Asia is considered to be distinct (Panthera leo persica). This distinction is disputed both by morphological and genetic data. In this study we introduce the lion as a model for African phylogeography. Analyses of mtDNA sequences reveal six supported clades and a strongly supported ancestral dichotomy with northern populations (West Africa, Central Africa, North Africa/Asia) on one branch, and southern populations (North East Africa, East/Southern Africa and South West Africa) on the other. We review taxonomies and phylogenies of other large savannah mammals, illustrating that similar clades are found in other species. The described phylogeographic pattern is considered in relation to large scale environmental changes in Africa over the past 300,000 years, attributable to climate. Refugial areas, predicted by climate envelope models, further confirm the observed pattern. We support the revision of current lion taxonomy, as recognition of a northern and a southern subspecies is more parsimonious with the evolutionary history of the lion. PMID:27488946

77 FR 2715 - D'Lo Gas Storage, LLC; Notice of Application

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-19

... Storage, LLC; Notice of Application Take notice that on December 29, 2011, D'Lo Gas Storage, LLC (D'Lo... natural gas storage project to be located in Simpson County, Mississippi. Additionally, D'Lo requests a...- discriminatory firm interruptible natural gas storage services and hub services, and a blanket certificate...

Evolution of Starspots on LO Pegasi

NASA Astrophysics Data System (ADS)

Harmon, Robert; Bloodgood, Felise; Martin, Alec; Pellegrin, Kyle

2018-01-01

LO Pegasi is a young solar analog, a K main-sequence star that rotates with a period of 10.1538 hr. The rapid rotation yields a strong stellar dynamo associated with large starspots on the surface, which are regions where the magnetic field inhibits the convective transport of energy from below, so that the spots are cooler and thus darker than the surrounding photosphere. The star thus exhibits rotational modulation of its light curve as the starspots are carried into and out of view of Earth. CCD images of LO Peg were acquired at Perkins Observatory in Delaware, OH through standard B, V, R, and I photometric filters from 2017 June 1 to July 20. After subtracting dark frames and flat fielding the images, differential aperture photometry was performed to yield light curves through each of the four filters. The resulting light curves that were then analyzed via the Light-curve Inversion program created by one of us (Harmon) to produce surface maps. Our observations indicated that LO Pegasi’s light curve changed in both amplitude and shape between 2017 June and July, while its maximum brightness did not change. We present maps corresponding to these two distinct light curves, along with maps for data acquired from 2006-2016.

PRIMA Platform capability for satellite missions in LEO and MEO (SAR, Optical, GNSS, TLC, etc.)

NASA Astrophysics Data System (ADS)

Logue, T.; L'Abbate, M.

2016-12-01

PRIMA (Piattaforma Riconfigurabile Italiana Multi Applicativa) is a multi-mission 3-axis stabilized Platform developed by Thales Alenia Space Italia under ASI contract.PRIMA is designed to operate for a wide variety of applications from LEO, MEO up to GEO and for different classes of satellites Platform Family. It has an extensive heritage in flight heritage (LEO and MEO Satellites already fully operational) in which it has successfully demonstrated the flexibility of use, low management costs and the ability to adapt to changing operational conditions.The flexibility and modularity of PRIMA provides unique capability to satisfy different Payload design and mission requirements, thanks to the utilization of recurrent adaptable modules (Service Module-SVM, Propulsion Module-PPM, Payload Module-PLM) to obtain mission dependent configuration. PRIMA product line development is continuously progressing, and is based on state of art technology, modular architecture and an Integrated Avionics. The aim is to maintain and extent multi-mission capabilities to operate in different environments (LEO to GEO) with different payloads (SAR, Optical, GNSS, TLC, etc.). The design is compatible with a wide range of European and US equipment suppliers, thus maximising cooperation opportunity. Evolution activities are mainly focused on the following areas: Structure: to enable Spacecraft configurations for multiple launch; Thermal Control: to guarantee thermal limits for new missions, more demanding in terms of environment and payload; Electrical: to cope with higher power demand (e.g. electrical propulsion, wide range of payloads, etc.) considering orbital environment (e.g. lighting condition); Avionics : AOCS solutions optimized on mission (LEO observation driven by agility and pointing, agility not a driver for GEO). Use of sensors and actuators tailored for specific mission and related environments. Optimised Propulsion control. Data Handling, SW and FDIR mission customization

Telemetry Tracking and Control Through Commercial LEO Satellites

NASA Technical Reports Server (NTRS)

Streich, Ronald C.; Morgan, Dwayne R.; Bull, Barton B.; Grant, Charles E.; Powers, Edward I. (Technical Monitor)

2001-01-01

Personnel from the Goddard Space Flight Center Wallops Flight Facility (GSFC/WFF in Virginia have successfully tested commercial LEO communications satellites for sounding rocket, balloon and aircraft flight TT&C. The Flight Modern became a GSFC/WFF Advanced Range Technology Initiative (ARTI) in an effort to streamline TT&C capability to the user community at low cost. Ground tests of the Flight Modem verified duplex communications quality of service and measured transmission latencies. These tests were completed last year and results reported in the John Hopkins University (JHU) Applied Physics Laboratory (APL) 4th International Symposium on Reducing Spacecraft Costs for Ground Systems and Operations. The second phase of the Flight Modem baseline test program was a demonstration of the ruggedized version of the WFF Flight Modem flown on a sounding rocket launched it the Swedish rocket range (Esrangc) near Kiruna, Sweden, with results contained in this paper. Aircraft flight tests have been and continue to be conducted. Flights of opportunity are being actively pursued with other centers, ranges and users at universities. The WFF Flight Modem contains a CPS receiver to provide vehicle position for tracking and vehicle recovery. The system architecture, which integrates antennas, CPS receiver, commercial satellite packet data modem and a single board computer with custom software, is described. Small satellite use of the WFF Flight Modem is also being investigated, The Flight Modem provides an independent vehicle position source for Range Safety applications. The LEO communication system contains a coarse position location system, which is compared to GPS ace acy. This comparison allows users, to determine the need for a CPS receiver in addition to the satellite packet data modem for their application.

Solar power satellite. System definition study. Part 1, volume 5: SPS transportation. Representative system descriptions

NASA Technical Reports Server (NTRS)

1977-01-01

Both LEO transportation (earth to low earth orbit) and GEO transportation (low earth orbit to geosynchronous orbit) segments were addressed. LEO options include both a 2 stage winged space freighter vehicle and a 2 stage ballistic recoverable vehicle. Both incorporate LO(2)/RP-1/LH(2) engines on the booster and standard SSME's on the upper stage. The orbit transfer vehicle options included chemical for geosynchronous satellite assembly and self powered electric propulsion for low earth orbit satellite assembly. An exhaust products analysis was conducted for the earth to LEO vehicle since atmospheric pollution could be a concern.

Re-Entry Point Targeting for LEO Spacecraft using Aerodynamic Drag

NASA Technical Reports Server (NTRS)

Omar, Sanny; Bevilacqua, Riccardo; Fineberg, Laurence; Treptow, Justin; Johnson, Yusef; Clark, Scott

2016-01-01

Most Low Earth Orbit (LEO) spacecraft do not have thrusters and re-enter atmosphere in random locations at uncertain times. Objects pose a risk to persons, property, or other satellites. Has become a larger concern with the recent increase in small satellites. Working on a NASA funded project to design a retractable drag device to expedite de-orbit and target a re-entry location through modulation of the drag area. Will be discussing the re-entry point targeting algorithm here.

Space environmental effects on spacecraft: LEO materials selection guide, part 1

NASA Astrophysics Data System (ADS)

Silverman, Edward M.

1995-08-01

This document provides performance properties on major spacecraft materials and subsystems that have been exposed to the low-Earth orbit (LEO) space environment. Spacecraft materials include metals, polymers, composites, white and black paints, thermal-control blankets, adhesives, and lubricants. Spacecraft subsystems include optical components, solar cells, and electronics. Information has been compiled from LEO short-term spaceflight experiments (e.g., space shuttle) and from retrieved satellites of longer mission durations (e.g., Long Duration Exposure Facility). Major space environment effects include atomic oxygen (AO), ultraviolet radiation, micrometeoroids and debris, contamination, and particle radiation. The main objective of this document is to provide a decision tool to designers for designing spacecraft and structures. This document identifies the space environments that will affect the performance of materials and components, e.g., thermal-optical property changes of paints due to UV exposures, AO-induced surface erosion of composites, dimensional changes due to thermal cycling, vacuum-induced moisture outgassing, and surface optical changes due to AO/UV exposures. Where appropriate, relationships between the space environment and the attendant material/system effects are identified. Part 1 covers spacecraft design considerations for the space environment; advanced composites; polymers; adhesives; metals; ceramics; protective coatings; and lubricants, greases, and seals.

Space environmental effects on spacecraft: LEO materials selection guide, part 1

NASA Technical Reports Server (NTRS)

Silverman, Edward M.

1995-01-01

This document provides performance properties on major spacecraft materials and subsystems that have been exposed to the low-Earth orbit (LEO) space environment. Spacecraft materials include metals, polymers, composites, white and black paints, thermal-control blankets, adhesives, and lubricants. Spacecraft subsystems include optical components, solar cells, and electronics. Information has been compiled from LEO short-term spaceflight experiments (e.g., space shuttle) and from retrieved satellites of longer mission durations (e.g., Long Duration Exposure Facility). Major space environment effects include atomic oxygen (AO), ultraviolet radiation, micrometeoroids and debris, contamination, and particle radiation. The main objective of this document is to provide a decision tool to designers for designing spacecraft and structures. This document identifies the space environments that will affect the performance of materials and components, e.g., thermal-optical property changes of paints due to UV exposures, AO-induced surface erosion of composites, dimensional changes due to thermal cycling, vacuum-induced moisture outgassing, and surface optical changes due to AO/UV exposures. Where appropriate, relationships between the space environment and the attendant material/system effects are identified. Part 1 covers spacecraft design considerations for the space environment; advanced composites; polymers; adhesives; metals; ceramics; protective coatings; and lubricants, greases, and seals.

Near-infrared Stellar Populations in the Metal-poor, Dwarf Irregular Galaxies Sextans A and Leo A

NASA Astrophysics Data System (ADS)

Jones, Olivia C.; Maclay, Matthew T.; Boyer, Martha L.; Meixner, Margaret; McDonald, Iain; Meskhidze, Helen

2018-02-01

We present JHK s observations of the metal-poor ([Fe/H] < ‑1.40) dwarf-irregular galaxies, Leo A and Sextans A, obtained with the WIYN High-resolution Infrared Camera at Kitt Peak. Their near-IR stellar populations are characterized by using a combination of color–magnitude diagrams and by identifying long-period variable stars. We detected red giant and asymptotic giant branch stars, consistent with membership of the galaxy’s intermediate-age populations (2–8 Gyr old). Matching our data to broadband optical and mid-IR photometry, we determine luminosities, temperatures, and dust-production rates (DPR) for each star. We identify 32 stars in Leo A and 101 stars in Sextans A with a DPR > {10}-11 {M}ȯ {yr}}-1, confirming that metal-poor stars can form substantial amounts of dust. We also find tentative evidence for oxygen-rich dust formation at low metallicity, contradicting previous models that suggest oxygen-rich dust production is inhibited in metal-poor environments. The total rates of dust injection into the interstellar medium of Leo A and Sextans A are (8.2+/- 1.8)× {10}-9 {M}ȯ {yr}}-1 and (6.2+/- 0.2)× {10}-7 {M}ȯ {yr}}-1, respectively. The majority of this dust is produced by a few very dusty evolved stars and does not vary strongly with metallicity.

An electrically conductive thermal control surface for spacecraft encountering Low-Earth Orbit (LEO) atomic oxygen indium tin oxide-coated thermal blankets

NASA Technical Reports Server (NTRS)

Bauer, J. L.

1987-01-01

An organic black thermal blanket material was coated with indium tin oxide (ITO) to prevent blanket degradation in the low Earth orbit (LEO) atomic oxygen environment. The blankets were designed for the Galileo spacecraft. Galileo was initially intended for space shuttle launch and would, therefore, have been exposed to atomic oxygen in LEO for between 10 and 25 hours. Two processes for depositing ITO are described. Thermooptical, electrical, and chemical properties of the ITO film are presented as a function of the deposition process. Results of exposure of the ITO film to atomic oxygen (from a shuttle flight) and radiation exposure (simulated Jovian environment) are also presented. It is shown that the ITO-protected thermal blankets would resist the anticipated LEO oxygen and Jovian radiation yet provide adequate thermooptical and electrical resistance. Reference is made to the ESA Ulysses spacecraft, which also used ITO protection on thermal control surfaces.

Measuring atmospheric density using GPS-LEO tracking data

NASA Astrophysics Data System (ADS)

Kuang, D.; Desai, S.; Sibthorpe, A.; Pi, X.

2014-01-01

We present a method to estimate the total neutral atmospheric density from precise orbit determination of Low Earth Orbit (LEO) satellites. We derive the total atmospheric density by determining the drag force acting on the LEOs through centimeter-level reduced-dynamic precise orbit determination (POD) using onboard Global Positioning System (GPS) tracking data. The precision of the estimated drag accelerations is assessed using various metrics, including differences between estimated along-track accelerations from consecutive 30-h POD solutions which overlap by 6 h, comparison of the resulting accelerations with accelerometer measurements, and comparison against an existing atmospheric density model, DTM-2000. We apply the method to GPS tracking data from CHAMP, GRACE, SAC-C, Jason-2, TerraSAR-X and COSMIC satellites, spanning 12 years (2001-2012) and covering orbital heights from 400 km to 1300 km. Errors in the estimates, including those introduced by deficiencies in other modeled forces (such as solar radiation pressure and Earth radiation pressure), are evaluated and the signal and noise levels for each satellite are analyzed. The estimated density data from CHAMP, GRACE, SAC-C and TerraSAR-X are identified as having high signal and low noise levels. These data all have high correlations with anominal atmospheric density model and show common features in relative residuals with respect to the nominal model in related parameter space. On the contrary, the estimated density data from COSMIC and Jason-2 show errors larger than the actual signal at corresponding altitudes thus having little practical value for this study. The results demonstrate that this method is applicable to data from a variety of missions and can provide useful total neutral density measurements for atmospheric study up to altitude as high as 715 km, with precision and resolution between those derived from traditional special orbital perturbation analysis and those obtained from onboard

Nickel-hydrogen LEO cycling at 20-50 percent DOD. [depth of discharge

NASA Technical Reports Server (NTRS)

Lowery, John E.; Mai, Jenny

1991-01-01

Two NiH2 two-cell packs made up of engineering cells built according to the Hubble Space Telescope design (EPI RNH 90-3) are currently being low-earth-orbit (LEO) cycled at 20-50 percent depth of discharge (DOD). The cells were manufactured by Eagle-Picher Industries, Inc., and activated with electrolyte (KOH) concentrations of 26 percent (pack No.1) and 31 percent (pack No.2), for use during evaluation of the HST cell design. The cells have been grouped according to electrolyte concentration but follow the same test schedule for comparison. This test was set up to study the behavior of NiH2 cells having differing electrolyte concentrations, when operated at relatively high DOD (20-50 percent) in a LEO cycling program. The test was designed specifically to allow the cells to pick their own recharge ratio for varying DOD and varying EOC (end of charge) voltages. The cells are being cycled in a simulated 96-min orbit with 60-min charge and 36-min discharge where an EOC cutoff voltage controls high-rate charging. EOC cutoff voltages vary between 1.48 V and 1.56 V.

Haemangiosarcoma in a captive Asiatic lion (Panthera leo persica)

PubMed Central

Vercammen, F.; Brandt, J.; Brantegem, L. Van; Bosseler, L.; Ducatelle, R.

2015-01-01

A 2.7-year-old male captive Asiatic lion (Panthera leo persica) died unexpectedly without preceding symptoms. Gross necropsy revealed liver and lung tumours, which proved to be haemangiosarcomas by histopathology. Some of the liver tumours were ruptured, leading to massive intra-abdominal haemorrhage and death. Haemangiosarcomas are rare in domestic and exotic felids, occurring in skin, thoracic-abdominal cavity and bones. Although these tumours mainly appear to be occurring in older cats, they are sometimes observed in younger animals, as in the present case. This is the first description of haemangiosarcoma in a young Asiatic lion. PMID:26623366

A Multi-epoch Kinematic Study of the Remote Dwarf Spheroidal Galaxy Leo II

DOE Office of Scientific and Technical Information (OSTI.GOV)

Spencer, Meghin E.; Mateo, Mario; Walker, Matthew G.

2017-02-20

We conducted a large spectroscopic survey of 336 red giants in the direction of the Leo II dwarf galaxy using Hectochelle on the Multiple Mirror Telescope, and we conclude that 175 of them are members based on their radial velocities and surface gravities. Of this set, 40 stars have never before been observed spectroscopically. The systemic velocity of the dwarf is 78.3 ± 0.6 km s{sup −1} with a velocity dispersion of 7.4 ± 0.4 km s{sup −1}. We identify one star beyond the tidal radius of Leo II but find no signatures of uniform rotation, kinematic asymmetries, or streams.more » The stars show a strong metallicity gradient of −1.53 ± 0.10 dex kpc{sup −1} and have a mean metallicity of −1.70 ± 0.02 dex. There is also evidence of two different chemodynamic populations, but the signal is weak. A larger sample of stars would be necessary to verify this feature.« less

New Results on RZ Leo and CC Scl

NASA Astrophysics Data System (ADS)

Szkody, Paula; Mukadam, Anjum S.; Gaensicke, Boris T.; Toloza, Odette; Dai, Zhibin; HST GO12870 Team

2017-01-01

Using HST COS ultraviolet spectra in time-tag mode and a long K2 observation, we have determined a spin period for the white in RZ Leo of 220 seconds, thus confirming this cataclysmic variable as a new member of the Intermediate Polar class of systems. The ultraviolet light curve of CC Scl at quiescence created from its COS spectral observations is dominated by its spin period of 195 seconds (that has only been previously observed during one of its outbursts). Spectra formed from the high and low sections of its light curve shows a temperature difference of several thousand degrees.PS and ASM acknowledge support from NASA grant HST-GO13807 and from NSF grant AST-1514737.

Commentary: Science, Technology, and Society in Guidelines for Using Technology to Prepare Social Studies Teachers--A Reply to Hicks et al. and Crocco and Leo

ERIC Educational Resources Information Center

Mason, Lance

2015-01-01

This essay is a response to both the "Guidelines for Using Technology to Prepare Social Studies Teachers" published in this journal by Hicks, Lee, Berson, Bolick, and Diem (2014) and the rejoinder by Crocco and Leo (2015). The author agrees with Crocco and Leo's assessment that removing the principal regarding science, technology, and…

Radiation environment at LEO orbits: MC simulation and experimental data.

NASA Astrophysics Data System (ADS)

Zanini, Alba; Borla, Oscar; Damasso, Mario; Falzetta, Giuseppe

The evaluations of the different components of the radiation environment in spacecraft, both in LEO orbits and in deep space is of great importance because the biological effect on humans and the risk for instrumentation strongly depends on the kind of radiation (high or low LET). That is important especially in view of long term manned or unmanned space missions, (mission to Mars, solar system exploration). The study of space radiation field is extremely complex and not completely solved till today. Given the complexity of the radiation field, an accurate dose evaluation should be considered an indispensable part of any space mission. Two simulation codes (MCNPX and GEANT4) have been used to assess the secondary radiation inside FO-TON M3 satellite and ISS. The energy spectra of primary radiation at LEO orbits have been modelled by using various tools (SPENVIS, OMERE, CREME96) considering separately Van Allen protons, the GCR protons and the GCR alpha particles. This data are used as input for the two MC codes and transported inside the spacecraft. The results of two calculation meth-ods have been compared. Moreover some experimental results previously obtained on FOTON M3 satellite by using TLD, Bubble dosimeter and LIULIN detector are considered to check the performances of the two codes. Finally the same experimental device are at present collecting data on the ISS (ASI experiment BIOKIS -nDOSE) and at the end of the mission the results will be compared with the calculation.

Real-Time Optical Surveillance of LEO/MEO with Small Telescopes

NASA Astrophysics Data System (ADS)

Zimmer, P.; McGraw, J.; Ackermann, M.

J.T. McGraw and Associates, LLC operates two proof-of-concept wide-field imaging systems to test novel techniques for uncued surveillance of LEO/MEO/GEO and, in collaboration with the University of New Mexico (UNM), uses a third small telescope for rapidly queued same-orbit follow-up observations. Using our GPU-accelerated detection scheme, the proof-of-concept systems operating at sites near and within Albuquerque, NM, have detected objects fainter than V=13 at greater than 6 sigma significance. This detection approximately corresponds to a 16 cm object with albedo of 0.12 at 1000 km altitude. Dozens of objects are measured during each operational twilight period, many of which have no corresponding catalog object. The two proof-of-concept systems, separated by ~30km, work together by taking simultaneous images of the same orbital volume to constrain the orbits of detected objects using parallax measurements. These detections are followed-up by imaging photometric observations taken at UNM to confirm and further constrain the initial orbit determination and independently assess the objects and verify the quality of the derived orbits. This work continues to demonstrate that scalable optical systems designed for real-time detection of fast moving objects, which can be then handed off to other instruments capable of tracking and characterizing them, can provide valuable real-time surveillance data at LEO and beyond, which substantively informs the SSA process.

Development of HiLo Microscope and its use in In-Vivo Applications

NASA Astrophysics Data System (ADS)

Patel, Shreyas J.

The functionality of achieving optical sectioning in biomedical research is invaluable as it allows for visualization of a biological sample at different depths while being free of background scattering. Most current microscopy techniques that offer optical sectioning, unfortunately, require complex instrumentation and thus are generally costly. HiLo microscopy, on the other hand, offers the same functionality and advantage at a relatively low cost. Hence, the work described in this thesis involves the design, build, and application of a HiLo microscope. More specifically, a standalone HiLo microscope was built in addition to implementing HiLo microscopy on a standard fluorescence microscope. In HiLo microscopy, optical sectioning is achieved by acquiring two different types of images per focal plane. One image is acquired under uniform illumination and the other is acquired under speckle illumination. These images are processed using an algorithm that extracts in-focus information and removes features and glare that occur as a result of background fluorescence. To show the benefits of the HiLo microscopy, several imaging experiments on various samples were performed under a HiLo microscope and compared against a traditional fluorescence microscope and a confocal microscope, which is considered the gold standard in optical imaging. In-vitro and ex-vivo imaging was performed on a set of pollen grains, and optically cleared mouse brain and heart slices. Each of these experiments showed great reduction in background scattering at different depths under HiLo microscopy. More importantly, HiLo imaging of optically cleared heart slice demonstrated emergence of different vasculature at different depths. Reduction of out-of-focus light increased the spatial resolution and allowed better visualization of capillary vessels. Furthermore, HiLo imaging was tested in an in-vivo model of a rodent dorsal window chamber model. When imaging the same sample under confocal microscope

Optically sectioned in vivo imaging with speckle illumination HiLo microscopy

PubMed Central

Lim, Daryl; Ford, Tim N.; Chu, Kengyeh K.; Mertz, Jerome

2011-01-01

We present a simple wide-field imaging technique, called HiLo microscopy, that is capable of producing optically sectioned images in real time, comparable in quality to confocal laser scanning microscopy. The technique is based on the fusion of two raw images, one acquired with speckle illumination and another with standard uniform illumination. The fusion can be numerically adjusted, using a single parameter, to produce optically sectioned images of varying thicknesses with the same raw data. Direct comparison between our HiLo microscope and a commercial confocal laser scanning microscope is made on the basis of sectioning strength and imaging performance. Specifically, we show that HiLo and confocal 3-D imaging of a GFP-labeled mouse brain hippocampus are comparable in quality. Moreover, HiLo microscopy is capable of faster, near video rate imaging over larger fields of view than attainable with standard confocal microscopes. The goal of this paper is to advertise the simplicity, robustness, and versatility of HiLo microscopy, which we highlight with in vivo imaging of common model organisms including planaria, C. elegans, and zebrafish. PMID:21280920

Optically sectioned in vivo imaging with speckle illumination HiLo microscopy.

PubMed

Lim, Daryl; Ford, Tim N; Chu, Kengyeh K; Mertz, Jerome

2011-01-01

We present a simple wide-field imaging technique, called HiLo microscopy, that is capable of producing optically sectioned images in real time, comparable in quality to confocal laser scanning microscopy. The technique is based on the fusion of two raw images, one acquired with speckle illumination and another with standard uniform illumination. The fusion can be numerically adjusted, using a single parameter, to produce optically sectioned images of varying thicknesses with the same raw data. Direct comparison between our HiLo microscope and a commercial confocal laser scanning microscope is made on the basis of sectioning strength and imaging performance. Specifically, we show that HiLo and confocal 3-D imaging of a GFP-labeled mouse brain hippocampus are comparable in quality. Moreover, HiLo microscopy is capable of faster, near video rate imaging over larger fields of view than attainable with standard confocal microscopes. The goal of this paper is to advertise the simplicity, robustness, and versatility of HiLo microscopy, which we highlight with in vivo imaging of common model organisms including planaria, C. elegans, and zebrafish.

Optically sectioned in vivo imaging with speckle illumination HiLo microscopy

NASA Astrophysics Data System (ADS)

Lim, Daryl; Ford, Tim N.; Chu, Kengyeh K.; Mertz, Jerome

2011-01-01

We present a simple wide-field imaging technique, called HiLo microscopy, that is capable of producing optically sectioned images in real time, comparable in quality to confocal laser scanning microscopy. The technique is based on the fusion of two raw images, one acquired with speckle illumination and another with standard uniform illumination. The fusion can be numerically adjusted, using a single parameter, to produce optically sectioned images of varying thicknesses with the same raw data. Direct comparison between our HiLo microscope and a commercial confocal laser scanning microscope is made on the basis of sectioning strength and imaging performance. Specifically, we show that HiLo and confocal 3-D imaging of a GFP-labeled mouse brain hippocampus are comparable in quality. Moreover, HiLo microscopy is capable of faster, near video rate imaging over larger fields of view than attainable with standard confocal microscopes. The goal of this paper is to advertise the simplicity, robustness, and versatility of HiLo microscopy, which we highlight with in vivo imaging of common model organisms including planaria, C. elegans, and zebrafish.

Impact of foliage on LoRa 433MHz propagation in tropical environment

NASA Astrophysics Data System (ADS)

Ahmad, Khairol Amali; Salleh, Mohd Sharil; Segaran, Jivitraa Devi; Hashim, Fakroul Ridzuan

2018-02-01

LoRa is being considered as one of the promising system for Low-Power-Wide-Area-Network (LPWAN) to support the growth of Internet of Things (IoT) applications. Designed to operate in the industrial, scientific and medical (ISM) bands, LoRa had been tested and evaluated mainly in Europe and US in the 868 MHz and 915 MHz modulation bands. Using chirp spread spectrum technology, LoRa is expected to be robust against degredation. This paper provides some early results in the performance of LoRa signal propagation of 433 MHz modulation in tropical foliage environments.

Optimization and throughput estimation of optical ground networks for LEO-downlinks, GEO-feeder links and GEO-relays

NASA Astrophysics Data System (ADS)

Fuchs, Christian; Poulenard, Sylvain; Perlot, Nicolas; Riedi, Jerome; Perdigues, Josep

2017-02-01

Optical satellite communications play an increasingly important role in a number of space applications. However, if the system concept includes optical links to the surface of the Earth, the limited availability due to clouds and other atmospheric impacts need to be considered to give a reliable estimate of the system performance. An OGS network is required for increasing the availability to acceptable figures. In order to realistically estimate the performance and achievable throughput in various scenarios, a simulation tool has been developed under ESA contract. The tool is based on a database of 5 years of cloud data with global coverage and can thus easily simulate different optical ground station network topologies for LEO- and GEO-to-ground links. Further parameters, like e.g. limited availability due to sun blinding and atmospheric turbulence, are considered as well. This paper gives an overview about the simulation tool, the cloud database, as well as the modelling behind the simulation scheme. Several scenarios have been investigated: LEO-to-ground links, GEO feeder links, and GEO relay links. The key results of the optical ground station network optimization and throughput estimations will be presented. The implications of key technical parameters, as e.g. memory size aboard the satellite, will be discussed. Finally, potential system designs for LEO- and GEO-systems will be presented.

First Asian record of Panthera (Leo) fossilis (Mammalia, Carnivora, Felidae) in the Early Pleistocene of Western Siberia, Russia.

PubMed

Sotnikova, Marina V; Foronova, Irina V

2014-08-01

A lion-like pantherine felid is described as Panthera (Leo) fossilis from the late Early Pleistocene sediments of the Kuznetsk Basin (Western Siberia, Russia). The find of P. fossilis first recorded in Asia considerably extends the current notion of the eastward expansion of the most ancient lions. The Siberian lion is geologically the oldest form and is dimensionally among the largest members of the group of fossil lions on the Eurasian continent. Although known by mandibular remains only, it is readily distinguished from Panthera (Leo) spelaea by a heavy built mandibular corpus with rectangular profile in the cheek teeth area, a deep, well-outlined and narrow anterior section of the masseteric fossa, and a large p4 supported by a big unreduced anterior root. The Siberian lion shares these features with the European Middle Pleistocene P. fossilis and the American Late Pleistocene P. (Leo) atrox, which suggests their close relationship. P. atrox originated from P. fossilis and was isolated in North America south of the Late Pleistocene ice sheets. This explains why the American lion has retained more primitive features than the coeval Eurasian cave lion P. (L.) spelaea. © 2013 International Society of Zoological Sciences, Institute of Zoology/Chinese Academy of Sciences and Wiley Publishing Asia Pty Ltd.

Robust Exploration and Commercial Missions to the Moon Using LANTR Propulsion and Lunar Liquid Oxygen Derived from FeO-Rich Pyroclastic Deposits

NASA Technical Reports Server (NTRS)

Borowski, Stanley K.; Ryan, Stephen W.; Burke, Laura M.; McCurdy, David R.; Fittje, James E.; Joyner, Claude R.

2017-01-01

Studies conducted by NASA and its contractors (early 1980s early 1990s) indicated a substantial benefit from using lunar-derived propellants specifically lunar-derived LO2 (LLO2) or LUNOX in a lunar space transportation system (LTS). With a LTS using LO2/LH2 chemical rockets, approx. 6 kilograms (kg) of mass in low Earth orbit (LEO) is required to place 1 kg of payload on the lunar surface (LS). Of this 6 kg, approx. 70% (4.2 kg) is propellant and 6/7th of this mass (3.6 kg) is oxygen assuming an O/H MR 6:1. Since the cost of placing a kilogram of mass on the LS is approx. 6X the cost of delivering it to LEO, the ability to produce and utilize LUNOX or lunar-derived LO2 and hydrogen (LLH2) from lunar polar ice (LPI) deposits can provide significant mission leverage. Providing LUNOX for use in fuel cells, life support systems and LO2/LH2 chemical rockets used on lunar landing vehicles (LLVs), can allow high value cargo (people, manufacturing and scientific equipment, etc.) to be transported to LEO, then to the Moon instead of bulk LO2 propellant. Oxygen is abundant in the lunar regolith (approx. 43% by mass) and can be extracted using a variety of techniques, such as hydrogen reduction of ilmenite (FeOTiO2) or FeO-rich volcanic glass (orange soil) discovered during the Apollo 17 mission to Taurus-Littrow. While considerable interest has been expressed about mining and processing LPI for rocket propellant, ground truth must first be established to quantify the physical state of the ice (e.g., its vertical thickness and areal extent, levels of soil contamination, etc.) and the deep, extremely cold (approx. 26-100 K) permanently shadowed craters where the ice resides.

Challenges and Solutions for GNSS Receivers onboard LEO Satellites Traveling through the Ionosphere during Space Weather Events

NASA Astrophysics Data System (ADS)

Morton, Y.; Xu, D.; Yang, R.; Jiao, Y.; Rino, C.; Carrano, C. S.

2017-12-01

This presentation discusses challenges imposed on GNSS receiver carrier-tracking loop for receivers onboard LEO satellites traveling through ionosphere during space weather events and techniques that mitigate the effects. Recent studies show that the ESA's swarm satellites experienced a total loss of GPS signals in areas known for frequent occurrence of ionosphere plasma irregularities. The same phenomena have been observed in other satellite missions. More robust GNSS receiver technologies are needed to improve the navigation capabilities for future LEO satellite missions. A major challenge to characterize GNSS signals traversing ionospheric plasma structures to reach a LEO satellite is the lack of data. To overcome this challenge, we utilized a physics-based GNSS scintillation signal simulator to generate simulated data for analysis and algorithm development. The simulator relies on real scintillation data collected by ground-based receivers as the initializer to generate a realization of ionosphere irregularity structure statistical distribution. A user specifies desired satellite orbit, signal modulation scheme, receiver platform dynamics, and receiver front-end hardware design. These inputs are used to establish the signal propagation geometry to allow interception of the disturbed signal by a realistic GNSS receiver. The simulator results showed that plasma structures lead to strong disturbances on GNSS signals reaching a LEO platform. The disturbances are characterized by simultaneous deep amplitude fades and extremely rapid carrier phase fluctuations. The carrier phase rate is orders of magnitude higher than the ones experienced by receivers on the ground. Such high carrier dynamics far exceeds the range that can be tolerated by the bandwidth of a typical GNSS receiver. The deep amplitude fades further exacerbate the problem. Based on the simulator outputs, we established models of the disturbed signal parameters. These models are used in an adaptive

Optically Sectioned Imaging of Microvasculature of In-Vivo and Ex-Vivo Thick Tissue Models with Speckle-illumination HiLo Microscopy and HiLo Image Processing Implementation in MATLAB Architecture

NASA Astrophysics Data System (ADS)

Suen, Ricky Wai

The work described in this thesis covers the conversion of HiLo image processing into MATLAB architecture and the use of speckle-illumination HiLo microscopy for use of ex-vivo and in-vivo imaging of thick tissue models. HiLo microscopy is a wide-field fluorescence imaging technique and has been demonstrated to produce optically sectioned images comparable to confocal in thin samples. The imaging technique was developed by Jerome Mertz and the Boston University Biomicroscopy Lab and has been implemented in our lab as a stand-alone optical setup and a modification to a conventional fluorescence microscope. Speckle-illumination HiLo microscopy combines two images taken under speckle-illumination and standard uniform-illumination to generate an optically sectioned image that reject out-of-focus fluorescence. The evaluated speckle contrast in the images is used as a weighting function where elements that move out-of-focus have a speckle contrast that decays to zero. The experiments shown here demonstrate the capability of our HiLo microscopes to produce optically-sectioned images of the microvasculature of ex-vivo and in-vivo thick tissue models. The HiLo microscope were used to image the microvasculature of ex-vivo mouse heart sections prepared for optical histology and the microvasculature of in-vivo rodent dorsal window chamber models. Studies in label-free surface profiling with HiLo microscopy is also presented.

Minimum Number of Observation Points for LEO Satellite Orbit Estimation by OWL Network

NASA Astrophysics Data System (ADS)

Park, Maru; Jo, Jung Hyun; Cho, Sungki; Choi, Jin; Kim, Chun-Hwey; Park, Jang-Hyun; Yim, Hong-Suh; Choi, Young-Jun; Moon, Hong-Kyu; Bae, Young-Ho; Park, Sun-Youp; Kim, Ji-Hye; Roh, Dong-Goo; Jang, Hyun-Jung; Park, Young-Sik; Jeong, Min-Ji

2015-12-01

By using the Optical Wide-field Patrol (OWL) network developed by the Korea Astronomy and Space Science Institute (KASI) we generated the right ascension and declination angle data from optical observation of Low Earth Orbit (LEO) satellites. We performed an analysis to verify the optimum number of observations needed per arc for successful estimation of orbit. The currently functioning OWL observatories are located in Daejeon (South Korea), Songino (Mongolia), and Oukaïmeden (Morocco). The Daejeon Observatory is functioning as a test bed. In this study, the observed targets were Gravity Probe B, COSMOS 1455, COSMOS 1726, COSMOS 2428, SEASAT 1, ATV-5, and CryoSat-2 (all in LEO). These satellites were observed from the test bed and the Songino Observatory of the OWL network during 21 nights in 2014 and 2015. After we estimated the orbit from systematically selected sets of observation points (20, 50, 100, and 150) for each pass, we compared the difference between the orbit estimates for each case, and the Two Line Element set (TLE) from the Joint Space Operation Center (JSpOC). Then, we determined the average of the difference and selected the optimal observation points by comparing the average values.

Home range establishment and utilization by reintroduced lions (Panthera leo) in a small South African wildlife reserve.

PubMed

Yiu, Sze-Wing; Parrini, Francesca; Karczmarski, Leszek; Keith, Mark

2017-07-01

Understanding of animal spatial behavior is essential for informed management decisions. In southern Africa, reintroduction of lions (Panthera leo) to small reserves (<1000 km 2 ) has increased since the early 2000s, however studies on their ranging behavior in these enclosed systems remain lacking. We applied Time Local Convex Hull (T-LoCoH) methods to study the home range establishment and utilization of 11 lions reintroduced to Dinokeng Game Reserve, South Africa, during 2011 through 2014. Lions established home ranges close to their release sites and during the following 3 years their home range sizes continued to increase, but in each individual case the size remained smaller than half of the reserve area (<70 km 2 ). Space use strategies differed between the core and the entire home range, with higher frequency of visits found in core areas. Exceptionally high rates (>60 separate visits) around the largest dam and along rivers suggest the importance of water and its surrounding vegetation in the lions' space utilization pattern. The home range size did not differ with season or sex of the individuals, whereas shifts in locations of home ranges revealed differences in the response of the 2 sexes to territorial conflicts and management interventions. Our study shows a dynamic home range utilization pattern and highlights the importance of both fine-scale space use patterns (frequency and duration of visits) and broad-scale home range changes in understanding the ranging behavior of reintroduced animals. © 2016 International Society of Zoological Sciences, Institute of Zoology/Chinese Academy of Sciences and John Wiley & Sons Australia, Ltd.

Liquid Oxygen (LO2) propellant conditioning concept testing

NASA Technical Reports Server (NTRS)

Perry, Gretchen L. E.; Orth, Michael S.; Mehta, Gopal K.

1993-01-01

Marshall Space Flight Center (MSFC) and industry contractors have undertaken activities to develop a simplified liquid oxygen (LO2) propellant conditioning concept for future expendable launch vehicles. The objective of these activities is to reduce operations costs and timelines and to improve safety of these vehicles. The approach followed has been to identify novel concepts through system level studies and demonstrate the feasibility of these concepts through small-scale and full-scale testing. Testing will also provide data for design guidelines and validation of analytical models. Four different concepts are being investigated: no-bleed, low-bleed, use of a recirculation line, and helium (He) bubbling. This investigation is being done under a Joint Institutional Research and Development (JIRAD) program currently in effect between MSFC and General Dynamics Space Systems (GDSS). A full-scale test article, which is a facsimile of a propellant feed duct with an attached section to simulate heat input from a LO2 turbopump, will be tested at the Cold Flow Facility at MSFC's West Test Area. Liquid nitrogen (LN2), which has similar properties to LO2, will be used in place of LO2 for safety and budget reasons. Work to date includes design and fabrication of the test article, design of the test facility and initial fabrication, development of a test matrix and test procedures, initial predictions of test output, and heat leak calibration and heat exchanger tests on the test article. The tests for all propellant conditioning concepts will be conducted in the summer of 1993, with the final report completed by October, 1993.

Low-Earth-Orbit (LEO) Life Cycle Evaluation of Nickel-Zinc Batteries

NASA Technical Reports Server (NTRS)

Coates, D.; Ferreira, E.; Nyce, M.; Charkey, A.

1997-01-01

The conclusion of the Low-Earth-Orbit (LEO) life cycle evaluation of nickel-zinc batteries are: that composite nickel electrode provide excellent performance at a reduced weight and lower cost; calcium / zinc electrode minimizes shape change; unioptimized cell designs yield 60 Wh/kg; nickel-zinc delivers 600 cycles at 80% DOD; long cycle life obtainable at low DOD; high rate capability power density; long-term failure mechanism is stack dry; and anomalous overcharge (1120%) greatly affected cell performance but did not induce failure and was recoverable.

Measurements of Multi-star Systems LEO 5 and MKT 13

NASA Astrophysics Data System (ADS)

AlZaben, Faisal; Priest, Allen; Priest, Stephen; Qiu, Rex; Boyce, Grady; Boyce, Pat

2016-04-01

We report measurements of the position angles and separations of two multi-star systems observed during the fall of 2015. Image data was obtained using an online 17-inch iTelescope system in Nerpio, Spain. Image data was analyzed using Maxim DL Pro 6 and Mira Pro x64 software tools at the Army and Navy Academy in Carlsbad, California. Our measurements of the LEO 5 system are consistent with historical data, although inconclusive as to the nature of the system. Our measurements and the historical data for the MKT 13 system show a consistent linearity in the position angle and separation.

Impedance measurements on a spiral-wound nickel/metal hydride cell cycled in a simulated Leo orbit

NASA Technical Reports Server (NTRS)

Reid, Margaret A.

1993-01-01

A spiral-wound size C cell was cycled at 25 C in a low earth orbit (LEO) regime at 50 percent depth of discharge (DOD) with approximately five percent over-charge. The nominal capacity was 3.5 AH. The cell was cycled for 2000 cycles. Capacity checks and impedance measurements over the complete range of state of charge were made upon receipt and after 500, 1000, and 2000 cycles. The capacity of the cell was essentially unchanged until after the impedance measurements at 2000 cycles. Only small changes in the impedance parameters were observed, but there was somewhat more scatter in the data after 2000 cycles. When the cell was returned to LEO cycling after 2000 cycles, only 38 percent of the capacity could be obtained. It is believed that the cell failed because of an equipment failure at the end of the final impedance measurements which allowed an over-discharge.

Measuring the Outflow Properties of FeLoBAL Quasars

NASA Astrophysics Data System (ADS)

Dabbieri, Collin; Choi, Hyunseop; MacInnis, Francis; Leighly, Karen; Terndrup, Donald

2018-01-01

Roughly 20 percent of the quasar population shows broad absorption lines, which are indicators of an energetic wind. Within the broad absorption line class of quasars exist FeLoBAL quasars, which show strong absorption lines from the Fe II and Fe III transitions as well as other low-ionization lines. FeLoBALs are of particular interest because they are thought to possibly be a short-lived stage in a quasar's life where it expels its shroud of gas and dust. This means the winds we see from FeLoBALs are one manifestation of galactic feedback. This idea is supported by Farrah et al. (2012) who found an anti correlation between outflow strength and contribution from star formation to the total IR luminosity of the host galaxy when examining a sample of FeLoBAL quasars. We analyze the sample of 26 FeLoBALs from Farrah et al. (2012) in order to measure the properties of their outflows, including ionization, density, column density and covering fraction. The absorption and continuum profiles of these objects are modeled using SimBAL, a program which creates synthetic spectra using a grid of Cloudy models. A Monte-Carlo method is employed to determine posterior probabilities for the physical parameters of the outflow. From these probabilities we extract the distance of the outflow, the mass outflow rate and the kinetic luminosity. We demonstrate SimBAL is capable of modeling a wide range of spectral morphologies. From the 26 objects studied we observe interesting correlations between ionization parameter, distance and density. Analysis of our sample also suggests a dearth of objects with velocity widths greater than or equal to 300 km/s at distances greater than or equal to 100 parsecs.

Laminarin-induced apoptosis in human colon cancer LoVo cells

PubMed Central

JI, CHEN-FENG; JI, YU-BIN

2014-01-01

A number of scientific studies have revealed that laminarin has antitumor effects. Therefore, the aim of the present study was to investigate the apoptosis of LoVo cells and the underlying mechanisms induced by laminarin. LoVo cells were treated with various concentrations of laminarin and fluorescence-inverted microscopy was used to observe the morphology of LoVo cells treated with laminarin. In addition, western blotting was performed to analyze the expression levels of death receptor (DR)4, DR5, TNF-related apoptosis-inducing ligand (TRAIL), Fas-associated protein with death domain (FADD), caspase-8, caspase-3, Bid and tBid. Flow cytometry was conducted to analyze the expressions of Bcl-2 and Bax, and spectrophotometry was performed to quantify the activity of caspases-8, -3, -6 and -7. Following the treatment of LoVo cells with laminarin for 24 h, the expression levels of DR4, DR5, TRAIL, FADD, Bid, tBid and Bax were observed to be upregulated, whereas the expression levels of pro-caspase-8, pro-caspase-3 and Bcl-2 were downregulated. In addition, the activities of casapse-8, -3, -6 and -7 were observed to increase, which was a significant difference when compared with those of the control group. Therefore, laminarin is considered to induce the apoptosis of LoVo cells, which may occur via a DR pathway, suggesting that laminarin may be a potent agent for cancer treatment. PMID:24765209

Laminarin-induced apoptosis in human colon cancer LoVo cells.

PubMed

Ji, Chen-Feng; Ji, Yu-Bin

2014-05-01

A number of scientific studies have revealed that laminarin has antitumor effects. Therefore, the aim of the present study was to investigate the apoptosis of LoVo cells and the underlying mechanisms induced by laminarin. LoVo cells were treated with various concentrations of laminarin and fluorescence-inverted microscopy was used to observe the morphology of LoVo cells treated with laminarin. In addition, western blotting was performed to analyze the expression levels of death receptor (DR)4, DR5, TNF-related apoptosis-inducing ligand (TRAIL), Fas-associated protein with death domain (FADD), caspase-8, caspase-3, Bid and tBid. Flow cytometry was conducted to analyze the expressions of Bcl-2 and Bax, and spectrophotometry was performed to quantify the activity of caspases-8, -3, -6 and -7. Following the treatment of LoVo cells with laminarin for 24 h, the expression levels of DR4, DR5, TRAIL, FADD, Bid, tBid and Bax were observed to be upregulated, whereas the expression levels of pro-caspase-8, pro-caspase-3 and Bcl-2 were downregulated. In addition, the activities of casapse-8, -3, -6 and -7 were observed to increase, which was a significant difference when compared with those of the control group. Therefore, laminarin is considered to induce the apoptosis of LoVo cells, which may occur via a DR pathway, suggesting that laminarin may be a potent agent for cancer treatment.

LoRa Scalability: A Simulation Model Based on Interference Measurements.

PubMed

Haxhibeqiri, Jetmir; Van den Abeele, Floris; Moerman, Ingrid; Hoebeke, Jeroen

2017-05-23

LoRa is a long-range, low power, low bit rate and single-hop wireless communication technology. It is intended to be used in Internet of Things (IoT) applications involving battery-powered devices with low throughput requirements. A LoRaWAN network consists of multiple end nodes that communicate with one or more gateways. These gateways act like a transparent bridge towards a common network server. The amount of end devices and their throughput requirements will have an impact on the performance of the LoRaWAN network. This study investigates the scalability in terms of the number of end devices per gateway of single-gateway LoRaWAN deployments. First, we determine the intra-technology interference behavior with two physical end nodes, by checking the impact of an interfering node on a transmitting node. Measurements show that even under concurrent transmission, one of the packets can be received under certain conditions. Based on these measurements, we create a simulation model for assessing the scalability of a single gateway LoRaWAN network. We show that when the number of nodes increases up to 1000 per gateway, the losses will be up to 32%. In such a case, pure Aloha will have around 90% losses. However, when the duty cycle of the application layer becomes lower than the allowed radio duty cycle of 1%, losses will be even lower. We also show network scalability simulation results for some IoT use cases based on real data.

The Fornax-Leo-Sculptor stream revisited

NASA Technical Reports Server (NTRS)

Majewski, Steven R.

1994-01-01

Lynden-Bell first demonstrated that the satellites of the Milky Way appear situated along two great 'streams' in the sky: the 'Magellanic stream' and the 'Fornax-Leo-Sculptor (FLS) stream.' Further exploration of the three-dimensional distribution of Galactic satellites reveals that the recently discovered Sextans and Phoenix dwarf spheroidal galaxies also lie near the plane defined by the FLS galaxies, and therefore strengthens the evidence in favor of the FLS stream. Moreover, a specific group of globular clusters -- those exhibiting the reddest horizontal branches (HBs) among those identified as 'young halo' by Zinn -- appear to populate the FLS stream. As previously demonstrated by Zinn, the spatial distribution of old halo globulars appears to be flattened toward the Galactic plane, and therefore the old halo clusters are typically anti-correlated to the nearly orthogonal FLS stream. A scenario is postulated wherein the Galactic satellites of the FLS stream and the red HB, young halo globular clusters share a common origin in the accretion of a formerly larger, parent satellite galaxy or Searle & Zinn 'fragment.'

Geocenter Motion Derived from GNSS and SLR Tracking Data of LEO

NASA Astrophysics Data System (ADS)

Li, Y. S.; Ning, F. S.; Tseng, K. H.; Tseng, T. P.; Wu, J. M.; Chen, K. L.

2017-12-01

Space geodesy techniques can provide the monitoring data of global variations with high precision and large coverage through the satellites. Geocenter motion (GM) describes the difference of CF (Center of Figure) respect to CM (Center of Mass of the Earth System) due to the re-distribution and deformation of the earth system. Because satellite tracking data between ground stations and satellites orbit around the CM, geocenter motion is related to the realization of the ITRF (International Terrestrial Reference Frame) origin. In this study, GPS (Global Positioning System) observation data of IGS (International GNSS Service) and SLR (Satellite Laser Ranging) tracking data are applied to estimate the coordinates of observing sites on Earth's surface. The GPS observing sites are distributed deliberately and globally by 15° ×15° grids. Meanwhile, two different global ocean tide models are applied here. The model used in ITRF comparison and combination is parameter transformation, which is a mathematical formula allowing to transform the different frames between ITRF and CM system. Following the parameter transformation, the results of geocenter motion can be determined. The FORMOSAT-7/COSMIC-2 (F7C2) mission is a constellation of LEO (Low-Earth-Orbit) satellites, which will be launched in 2018. Besides the observing system for Meteorology, Ionosphere, and Climate, the F7C2 will be equipped with LRR (Laser Ranging Retroreflector). This work is a pilot survey to study the application of LEO SLR data in Taiwan.

Analyzing speckle contrast for HiLo microscopy optimization.

PubMed

Mazzaferri, J; Kunik, D; Belisle, J M; Singh, K; Lefrançois, S; Costantino, S

2011-07-18

HiLo microscopy is a recently developed technique that provides both optical sectioning and fast imaging with a simple implementation and at a very low cost. The methodology combines widefield and speckled illumination images to obtain one optically sectioned image. Hence, the characteristics of such speckle illumination ultimately determine the quality of HiLo images and the overall performance of the method. In this work, we study how speckle contrast influence local variations of fluorescence intensity and brightness profiles of thick samples. We present this article as a guide to adjust the parameters of the system for optimizing the capabilities of this novel technology.

Analyzing speckle contrast for HiLo microscopy optimization

NASA Astrophysics Data System (ADS)

Mazzaferri, J.; Kunik, D.; Belisle, J. M.; Singh, K.; Lefrançois, S.; Costantino, S.

2011-07-01

HiLo microscopy is a recently developed technique that provides both optical sectioning and fast imaging with a simple implementation and at a very low cost. The methodology combines widefield and speckled illumination images to obtain one optically sectioned image. Hence, the characteristics of such speckle illumination ultimately determine the quality of HiLo images and the overall performance of the method. In this work, we study how speckle contrast influence local variations of fluorescence intensity and brightness profiles of thick samples. We present this article as a guide to adjust the parameters of the system for optimizing the capabilities of this novel technology.

Performance Evaluation of Low Cost LoRa Modules in IoT Applications

NASA Astrophysics Data System (ADS)

Daud, Shuhaizar; Shi Yang, Teoh; Asmi Romli, Muhamad; Awang Ahmad, Zahari; Mahrom, Norfadila; Raof, Rafikha Aliana A.

2018-03-01

LoRa is a low power long range wireless communication platform that is designed as an efficient communication platform for small, low powered devices. This makes it very suitable for battery powered devices and IoT implementation. This paper evaluates some low cost LoRa modules available on the market and their suitability, energy efficiency and performance during operation. Two low cost LoRa transceiver from Semtech Industries, the SX1272 and SX1278 were tested for their power consumption and maximum transmission range. This study have evaluated the two LoRa solutions and found that the SX1278 have a better transmission range and uses lower energy compared to the SX1272 thus making it more suitable for embedded implementation as a data gateway.

LoRa Scalability: A Simulation Model Based on Interference Measurements

PubMed Central

Haxhibeqiri, Jetmir; Van den Abeele, Floris; Moerman, Ingrid; Hoebeke, Jeroen

2017-01-01

LoRa is a long-range, low power, low bit rate and single-hop wireless communication technology. It is intended to be used in Internet of Things (IoT) applications involving battery-powered devices with low throughput requirements. A LoRaWAN network consists of multiple end nodes that communicate with one or more gateways. These gateways act like a transparent bridge towards a common network server. The amount of end devices and their throughput requirements will have an impact on the performance of the LoRaWAN network. This study investigates the scalability in terms of the number of end devices per gateway of single-gateway LoRaWAN deployments. First, we determine the intra-technology interference behavior with two physical end nodes, by checking the impact of an interfering node on a transmitting node. Measurements show that even under concurrent transmission, one of the packets can be received under certain conditions. Based on these measurements, we create a simulation model for assessing the scalability of a single gateway LoRaWAN network. We show that when the number of nodes increases up to 1000 per gateway, the losses will be up to 32%. In such a case, pure Aloha will have around 90% losses. However, when the duty cycle of the application layer becomes lower than the allowed radio duty cycle of 1%, losses will be even lower. We also show network scalability simulation results for some IoT use cases based on real data. PMID:28545239

G-LoSA for Prediction of Protein-Ligand Binding Sites and Structures.

PubMed

Lee, Hui Sun; Im, Wonpil

2017-01-01

Recent advances in high-throughput structure determination and computational protein structure prediction have significantly enriched the universe of protein structure. However, there is still a large gap between the number of available protein structures and that of proteins with annotated function in high accuracy. Computational structure-based protein function prediction has emerged to reduce this knowledge gap. The identification of a ligand binding site and its structure is critical to the determination of a protein's molecular function. We present a computational methodology for predicting small molecule ligand binding site and ligand structure using G-LoSA, our protein local structure alignment and similarity measurement tool. All the computational procedures described here can be easily implemented using G-LoSA Toolkit, a package of standalone software programs and preprocessed PDB structure libraries. G-LoSA and G-LoSA Toolkit are freely available to academic users at http://compbio.lehigh.edu/GLoSA . We also illustrate a case study to show the potential of our template-based approach harnessing G-LoSA for protein function prediction.

Tamoxifen-loaded lecithin organogel (LO) for topical application: Development, optimization and characterization.

PubMed

Bhatia, Amit; Singh, Bhupinder; Raza, Kaisar; Wadhwa, Sheetu; Katare, Om Prakash

2013-02-28

Lecithin organogels (LOs) are semi-solid systems with immobilized organic liquid phase in 3-D network of self-assembled gelators. This paper attempts to study the various attributes of LOs, starting from selection of materials, optimization of influential components to LO specific characterization. After screening of various components (type of gelators, organic and aqueous phase) and construction of phase diagrams, a D-optimal mixture design was employed for the systematic optimization of the LO composition. The response surface plots were constructed for various response variables, viz. viscosity, gel strength, spreadability and consistency index. The optimized LO composition was searched employing overlay plots. Subsequent validation of the optimization study employing check-point formulations, located using grid search, indicated high degree of prognostic ability of the experimental design. The optimized formulation was characterized for morphology, drug content, rheology, spreadability, pH, phase transition temperatures, and physical and chemical stability. The outcomes of the study were interesting showing high dependence of LO attributes on the type and amount of phospholipid, Poloxamer™, auxillary gelators and organic solvent. The optimized LO was found to be quite stable, easily applicable and biocompatible. The findings of the study can be utilized for the development of LO systems of other drugs for the safer and effective topical delivery. Crown Copyright © 2013. Published by Elsevier B.V. All rights reserved.

Archean evolution of the Leo Rise and its Eburnean reworking

NASA Astrophysics Data System (ADS)

Thiéblemont, Denis; Goujou, Jean Christian; Egal, Emmanuel; Cocherie, Alain; Delor, Claude; Lafon, Jean Michel; Fanning, C. Mark

2004-06-01

Recent geological mapping in southeastern Guinea, supported by zircon dating, has called into question traditional understanding concerning the evolution of the Leo Rise. Gneiss dated at about 3540 Ma appears to constitute the earliest evidence for continental accretion within the Leo Rise. The existence of a Leonian depositional cycle at about 3000 Ma is confirmed, marked by volcanic and sedimentary rocks that can be correlated with the Loko Group in Sierra Leone. The span of ages (3244-3050 Ma) suggests that the Leonian cycle comprises different episodes whose respective chronology is as yet uncertain. Clearly distinct from the Leonian cycle, the Liberian cycle (˜2900-2800 Ma) is represented in Guinea by granite and migmatite (˜2910-2800 Ma), reflecting remobilization of the ancient Archean basement and deformation of the Leonian rocks; no deposition is associated with this cycle. After the Liberian, the Nimba and Simandou successions, containing Liberian detrital zircons, are assigned to the Birimian (˜2200-2000 Ma). Finally, Eburnean tectonism caused intense deformation of the Archean craton, accompanied by high-grade metamorphism and the intrusion of granite and syenite with ages between 2080 and 2020 Ma. The evolution of the Kénéma-Man domain, attributed to the cumulated effect of the Leonian and Liberian cycles, is thus in part Eburnean. We can suppose, therefore, that the NNE-SSW-trending structures attributed to the Liberian in Sierra Leone are, in fact, Eburnean. The Kambui Supergroup, also affected by this tectonism, should thus be assigned to the Birimian rather than the Liberian, which would explain its similarities with the Nimba and Simandou successions.

LoTi Turns Up the Heat!

ERIC Educational Resources Information Center

Moersch, Christopher

2010-01-01

When LoTi was first introduced in 1994 as the Levels of Technology Implementation framework, the intent was to create a tool to help district leadership quantify how teachers were using technology in the classroom. After serving the past 15 years as a research framework, self-reporting technology integration survey, and school improvement model,…

Evaluation of the night sky quality at El Leoncito and LEO++ in Argentina

NASA Astrophysics Data System (ADS)

Aubé, Martin; García, Beatriz; Fortin, Nicolas; Turcotte, Sara; Mancilla, Alexis; Maya, Javier

2015-08-01

Light pollution is a growing concern at many levels, but especially for the astronomical community. Artificial lighting veil celestial objects and disturbs the measurement of night time atmospheric phenomena. This is what motivates our sky brightness measurement experiment in Argentina. Our goal was to determine the quality of two Argentinian observation sites: LEO++ and El Leoncito. Both sites were candidates to host the Cherenkov Telescope Array (CTA). This project consists of an arrangement of many telescopes that can measure high-energy gamma ray emissions via their Cherenkov radiation produced when entering the earth's atmosphere. Even if the two argentinian sites has been excluded from the final CTA site competition, they are still of great interest for other astronomical projects. Especially the El Leoncito site which already hots the CASLEO astronomical complex. In this presentation, we describe the measurement methods used to determine the sky quality. We compared our results with different renowned astronomical sites (Kitt Peak, Arizona, USA, and Mont-Mégantic, Canada). Amongst our results, we found that LEO++ is a high quality site, however there are a lot of aerosols that can interfere with the measurements. El Leoncito shows very low sky brightness levels, which are optimal for low light level detection.

8-12 GHz Radio Observations of Flare Activity On M dwarf CN Leo

NASA Astrophysics Data System (ADS)

Wofford, Alia; Villadsen, Jackie; Quintana, Elisa; Barclay, Thomas; Thackeray, Beverly

2018-01-01

Red dwarfs are cool stars that make up 70% of all stars. Red dwarfs can be utilized to detect potentially habitable planets but they have particularly strong magnetic activity that can be detrimental to orbiting planets’ atmospheres and habitability. A coronal mass ejection (CME) is an eruption of magnetized plasma from the star that is ejected into the interplanetary medium which can erode a planet’s atmosphere daily. Based on the sun CMEs are expected to produce very bright radio bursts along with optical flares. We are using M dwarf CN Leo, a well studied flare star that was in the K2 campaign field in summer 2017, as a template to understand the relationship between radio and optical flares and the space weather conditions impacting M dwarf planets. Using radio frequencies ranging from 0.22 GHz-12 GHz we search for simultaneous radio bursts and optical flares to infer if CMEs, flares or aurorae are occurring on the star. I will present the 8-12 GHz radio data from eight 1.5-hour observations with simultaneous optical data. CN Leo produced a bright non-thermal radio flare that lasted approximately for a day during two consecutive observations, with a gyrosynchrotron emission mechanism.

The voltage threshold for arcing for solar cells in Leo - Flight and ground test results

NASA Technical Reports Server (NTRS)

Ferguson, Dale C.

1986-01-01

Ground and flight results of solar cell arcing in low earth orbit (LEO) conditions are compared and interpreted. It is shown that an apparent voltage threshold for arcing may be produced by a storage power law dependence of arc rate on voltage, combined with a limited observation time. The change in this apparent threshold with plasma density is a reflection of the density dependence of the arc rate. A nearly linear dependence of arc rate on density is inferred from the data. A real voltage threshold for arcing for 2 by 2 cm solar cells may exist however, independent of plasma density, near -230 V relative to the plasma. Here, arc rates may change by more than an order of magnitude for a change of only 30 V in array potential. For 5.9 by 5.9 solar cells, the voltage dependence of the arc rate is steeper, and the data are insufficient to indicate the existence of an arcing increased by an atomic oxygen plasma, as is found in LEO, and by arcing from the backs of welded-through substrates.

The voltage threshold for arcing for solar cells in LEO: Flight and ground test results

NASA Technical Reports Server (NTRS)

Ferguson, D. C.

1986-01-01

Ground and flight results of solar cell arcing in low Earth orbit (LEO) conditions are compared and interpreted. It is shown that an apparent voltage threshold for arcing may be produced by a strong power law dependence of arc rate on voltage, combined with a limited observation time. The change in this apparent threshold with plasma density is a reflection of the density dependence of the arc rate. A nearly linear dependence of arc rate on density is inferred from the data. A real voltage threshold for arcing for 2 by 2 cm solar cells may exist however, independent of plasma density, near -230 V relative to the plasma. Here, arc rates may change by more than an order of magnitude for a change of only 30 V in array potential. For 5.9 by 5.9 solar cells, the voltage dependence of the arc rate is steeper, and the data are insufficient to indicate the existence of an arcing increased by an atomic oxygen plasma, as is found in LEO, and by arcing from the backs of welded-through substrates.

EcAMSat and BioSentinel: Autonomous Bio Nanosatellites Addressing Strategic Knowledge Gaps for Manned Spaceflight Beyond LEO

NASA Technical Reports Server (NTRS)

Padgen, Michael R.

2017-01-01

Manned missions beyond low Earth orbit (LEO) require that several strategic knowledge gaps about the effects of space travel on the human body be addressed. NASA Ames Research Center has been the leader in developing autonomous bio nanosatellites, including past successful missions for GeneSat, PharmaSat, and O/OREOS, that tackled some of these issues. These nanosatellites provide in situ measurements, which deliver insight into the dynamic changes in cell behavior in microgravity. In this talk, two upcoming bio nanosatellites developed at Ames, the E. coli Antimicrobial Satellite (EcAMSat) and BioSentinel, will be discussed. Both satellites contain microfluidic systems that precisely deliver nutrients to the microorganisms stored within wells of fluidic cards. Each well, in turn, has its own 3-color LED and detector system which is used to monitor changes in metabolic activity with alamarBlue, a redox indicator, and the optical density of the cells. EcAMSat investigates the effects of microgravity on bacterial resistance to antimicrobial drugs, vital knowledge for understanding how to maintain the health of astronauts in long-term and beyond LEO spaceflight. The behavior of wild type and mutant uropathic E. coli will be compared in microgravity and with ground data to help understand the molecular mechanisms behind antibiotic resistance and how these phenotypes might change in space. BioSentinel seeks to directly measure the effects of space radiation on budding yeast S. cerevisiae, particularly double strand breaks (DSB). While hitching a ride on the SLS EM-1 mission (Orion's first unmanned mission to the moon) in 2018, BioSentinel will be kicked off and enter into a heliocentric orbit, becoming the first study of the effects of radiation on living organisms outside LEO since the Apollo program. The yeast are stored in eighteen independent 16-well microfluidic cards, which will be individually activated over the 12 month mission duration. In addition to the wild

EcAMSat and BioSentinel: Autonomous Bio Nanosatellites Addressing Strategic Knowledge Gaps for Manned Spaceflight Beyond LEO

NASA Technical Reports Server (NTRS)

Padgen, Mike

2017-01-01

Manned missions beyond low Earth orbit (LEO) require that several strategic knowledge gaps about the effects of space travel on the human body be addressed. NASA Ames Research Center has been the leader in developing autonomous bio nanosatellites, including past successful missions for GeneSat, PharmaSat, and OOREOS, that tackled some of these issues. These nanosatellites provide in situ measurements, which deliver insight into the dynamic changes in cell behavior in microgravity. In this talk, two upcoming bio nanosatellites developed at Ames, the E. coli Antimicrobial Satellite (EcAMSat) and BioSentinel, will be discussed. Both satellites contain microfluidic systems that precisely deliver nutrients to the microorganisms stored within wells of fluidic cards. Each well, in turn, has its own 3-color LED and detector system which is used to monitor changes in metabolic activity with alamarBlue, a redox indicator, and the optical density of the cells. EcAMSat investigates the effects of microgravity on bacterial resistance to antimicrobial drugs, vital knowledge for understanding how to maintain the health of astronauts in long-term and beyond LEO spaceflight. The behavior of wild type and mutant uropathic E. coli will be compared in microgravity and with ground data to help understand the molecular mechanisms behind antibiotic resistance and how these phenotypes might change in space. BioSentinel seeks to directly measure the effects of space radiation on budding yeast S. cerevisiae, particularly double strand breaks (DSB). While hitching a ride on the SLS EM-1 mission (Orions first unmanned mission to the moon) in 2018, BioSentinel will be kicked off and enter into a heliocentric orbit, becoming the first study of the effects of radiation on living organisms outside LEO since the Apollo program. The yeast are stored in eighteen independent 16-well microfluidic cards, which will be individually activated over the 12 month mission duration. In addition to the wild

Posthumous Testimony for Dr. Leo Gross and his Family / Restoration of the 'Lost' Biography of a Physician Victim of the Holocaust

PubMed

Hildebrandt, Sabine; Von Villiez, Anna; Seidelman, William E

At a time when the last direct witnesses of the Holocaust are passing, new approaches to the restoration of 'lost' biographies of victims need to be considered. This investigation describes the potential of an international collaboration including surviving family members. Archival documents discovered in Jerusalem in 1983 concerned a discussion on the cancellation of a medical licence for a German Jewish physician, Dr. Leo Gross of Kolberg, who had been disenfranchised from medical practice under Nazi law. After applying for a medical licence during a 1935 visit to Palestine, Gross remigrated to Germany, where he was imprisoned in a concentration camp. No further information was found until 2014, when a group of scholars linked a variety of archival and internet-accessible sources and located a nephew of Gross. The nephew's testimony, cross-referenced against data from other sources, enabled the reconstruction of the 'lost' biography of his uncle and family, in fact a posthumous testimony. The resulting narrative places Dr. Leo Gross within his professional and social network, and serves his commemoration within this context of family and community. The restored biography of Dr. Leo Gross presents an exemplary case study for the future of Holocaust testimony.

Leo Kanner's Mention of 1938 in His Report on Autism Refers to His First Patient

ERIC Educational Resources Information Center

Olmsted, Dan; Blaxill, Mark

2016-01-01

Leo Kanner begins his landmark 1943 case series on autistic children by stating the condition was first brought to his attention in 1938. Recent letters to "JADD" have described this reference as "mysterious" and speculated it refers to papers published that year by Despert or Asperger. In fact, as Kanner goes on to state, 1938…

LoCuSS: Testing hydrostatic equilibrium in galaxy clusters

NASA Astrophysics Data System (ADS)

Smith, G. P.; Mazzotta, P.; Okabe, N.; Ziparo, F.; Mulroy, S. L.; Babul, A.; Finoguenov, A.; McCarthy, I. G.; Lieu, M.; Bahé, Y. M.; Bourdin, H.; Evrard, A. E.; Futamase, T.; Haines, C. P.; Jauzac, M.; Marrone, D. P.; Martino, R.; May, P. E.; Taylor, J. E.; Umetsu, K.

2016-02-01

We test the assumption of hydrostatic equilibrium in an X-ray luminosity selected sample of 50 galaxy clusters at 0.15 < z < 0.3 from the Local Cluster Substructure Survey (LoCuSS). Our weak-lensing measurements of M500 control systematic biases to sub-4 per cent, and our hydrostatic measurements of the same achieve excellent agreement between XMM-Newton and Chandra. The mean ratio of X-ray to lensing mass for these 50 clusters is β_X= 0.95± 0.05, and for the 44 clusters also detected by Planck, the mean ratio of Planck mass estimate to LoCuSS lensing mass is β_P= 0.95± 0.04. Based on a careful like-for-like analysis, we find that LoCuSS, the Canadian Cluster Comparison Project, and Weighing the Giants agree on β_P ≃ 0.9-0.95 at 0.15 < z < 0.3. This small level of hydrostatic bias disagrees at ˜5σ with the level required to reconcile Planck cosmology results from the cosmic microwave background and galaxy cluster counts.

Near-IR Spectroscopy of Luminous LoBAL Quasars at 1 < z < 2.5

NASA Astrophysics Data System (ADS)

Schulze, Andreas; Schramm, Malte; Zuo, Wenwen; Wu, Xue-Bing; Urrutia, Tanya; Kotilainen, Jari; Reynolds, Thomas; Terao, Koki; Nagao, Tohru; Izumiura, Hideyuki

2017-10-01

We present near-IR spectroscopy of 22 luminous low-ionization broad absorption line quasars (LoBAL QSOs) at redshift 1.3< z< 2.5, with 12 objects at z ˜ 1.5 and 10 at z ˜ 2.3. The spectra cover the rest-frame Hα and Hβ line regions, allowing us to obtain robust black hole mass estimates based on the broad Hα line. We use these data, augmented by a lower-redshift sample from the Sloan Digital Sky Survey, to test the proposed youth scenario for LoBALs, which suggests that LoBALs constitute an early short-lived evolutionary stage of quasar activity, by probing for any difference in their masses, Eddington ratios, or rest-frame optical spectroscopic properties compared to normal quasars. In addition, we construct the UV to mid-IR spectral energy distributions (SEDs) for the LoBAL sample and a matched non-BAL quasar sample. We do not find any statistically significant difference between LoBAL QSOs and non-BAL QSOs in their black hole mass or Eddington ratio distributions. The mean UV to mid-IR SED of the LoBAL QSOs is consistent with non-BAL QSOs, apart from their stronger reddening. At z> 1 there is no clear difference in their optical emission line properties. We do not see particularly weak [O III] or strong Fe II emission. The LoBAL QSOs do not show a stronger prevalence of ionized gas outflows as traced by the [O III] line, compared to normal QSOs of similar luminosity. We conclude that the optical-MIR properties of LoBAL QSOs are consistent with the general quasar population and do not support them to constitute a special phase of active galactic nucleus evolution.

Leo Szilard In Physics and Information

NASA Astrophysics Data System (ADS)

Garwin, Richard

2014-03-01

The excellent biography by William Lanouette, ``Genius in the Shadows,'' tells it the way it was, incredible though it may seem. The 1972 ``Collected Works of Leo Szilard: Scientific Papers'' Bernard T. Feld and Getrude W. Szilard, Editors, gives the source material both published and unpublished. Szilard's path-breaking but initially little-noticed 1929 paper, ``On the Decrease of Entropy in a Thermodynamic System by the Intervention of Intelligent Beings'' spawned much subsequent research. It connected what we now call a bit of information with a quantity k ln 2 of entropy, and showed that the process of acquiring, exploiting, and resetting this information in a one-molecule engine must dissipate at least kT ln 2 of energy at temperature T. His 1925 paper, ``On the Extension of Phenomenological Thermodynamics to Fluctuation Phenomena,'' showed that fluctuations were consistent with and predicted from equilibrium thermodynamics and did not depend on atomistic theories. His work on physics and technology, demonstrated an astonishing range of interest, ingenuity, foresight, and practical sense. I illustrate this with several of his fundamental contributions nuclear physics, to the neutron chain reaction and to nuclear reactors, and also to electromagnetic pumping of liquid metals.

Liquid oxygen (LO2) propellant conditioning concept testing

NASA Technical Reports Server (NTRS)

Perry, Gretchen L. E.; Orth, Michael S.; Mehta, Gopal K.

1993-01-01

Testing of a simplified LO2 propellant conditioning concept for future expendable launch vehicles is discussed. Four different concepts are being investigated: no-bleed, low-bleed, use of a recirculation line, and He bubbling. A full-scale test article, which is a facsimile of a propellant feed duct with an attached section to simulate heat input from an LO2 turbopump, is to be tested at the Cold Flow Facility of the Marshall Space Flight Center West Test Area. Work to date includes: design and fabrication of the test article, design of the test facility and initial fabrication, development of a test matrix and test procedures, initial predictions of test output, and heat leak calibration and heat exchanger tests on the test articles.

Modeling of LEO Orbital Debris Populations in Centimeter and Millimeter Size Regimes

NASA Technical Reports Server (NTRS)

Xu, Y.-L.; Hill, . M.; Horstman, M.; Krisko, P. H.; Liou, J.-C.; Matney, M.; Stansbery, E. G.

2010-01-01

The building of the NASA Orbital Debris Engineering Model, whether ORDEM2000 or its recently updated version ORDEM2010, uses as its foundation a number of model debris populations, each truncated at a minimum object-size ranging from 10 micron to 1 m. This paper discusses the development of the ORDEM2010 model debris populations in LEO (low Earth orbit), focusing on centimeter (smaller than 10 cm) and millimeter size regimes. Primary data sets used in the statistical derivation of the cm- and mm-size model populations are from the Haystack radar operated in a staring mode. Unlike cataloged objects of sizes greater than approximately 10 cm, ground-based radars monitor smaller-size debris only in a statistical manner instead of tracking every piece. The mono-static Haystack radar can detect debris as small as approximately 5 mm at moderate LEO altitudes. Estimation of millimeter debris populations (for objects smaller than approximately 6 mm) rests largely on Goldstone radar measurements. The bi-static Goldstone radar can detect 2- to 3-mm objects. The modeling of the cm- and mm-debris populations follows the general approach to developing other ORDEM2010-required model populations for various components and types of debris. It relies on appropriate reference populations to provide necessary prior information on the orbital structures and other important characteristics of the debris objects. NASA's LEO-to-GEO Environment Debris (LEGEND) model is capable of furnishing such reference populations in the desired size range. A Bayesian statistical inference process, commonly adopted in ORDEM2010 model-population derivations, changes a priori distribution into a posteriori distribution and thus refines the reference populations in terms of data. This paper describes key elements and major steps in the statistical derivations of the cm- and mm-size debris populations and presents results. Due to lack of data for near 1-mm sizes, the model populations of 1- to 3.16-mm

VizieR Online Data Catalog: BVR light curves of UZ Leo (Lee+, 2018)

NASA Astrophysics Data System (ADS)

Lee, J. W.; Park, J.-H.

2018-04-01

We performed new CCD photometry of UZ Leo during two observing seasons between 2012 February and 2013 April, using a PIXIS: 2048B CCD and a BVR filter set attached to the 61 cm reflector at Sobaeksan Optical Astronomy Observatory (SOAO) in Korea. The CCD chip has 2048x2048pixels and a pixel size of 13.5um, so the field of view of a CCD frame is 17.6'x17.6'. (1 data file).

NiH2 Battery Reconditioning for LEO Applications

NASA Technical Reports Server (NTRS)

Armantrout, J. D.; Hafen, D. P.

1997-01-01

This paper summarizes reasons for and benefits of reconditioning nickel-hydrogen (NiH2) batteries used for Low Earth Orbit (LEO) applications. NiH2 battery cells do not have the classic discharge voltage problems more commonly associated with nickel-cadmium (NiCd) cells. This is due, in part, to use of hydrogen electrodes in place of cadmium electrodes. The nickel electrode, however, does have a similar discharge voltage signature for both cell designs. This can have an impact on LEO applications where peak loads at higher relative depths of discharge can impact operations. Periodic reconditioning provides information which can be used for analyzing long term performance trends to predict usable capacity to a specified voltage level. The reconditioning process described herein involves discharging NiH2 batteries at C/20 rates or less, to an average cell voltage of 1.0 volts or less. Recharge is performed at nominal C/5 rates to specified voltage/temperature (V/T) charge levels selected to restore required capacity with minimal overcharge. Reconditioning is a process of restoring reserve capacity lost on cycling, which is commonly called the memory effect in NiCd cells. This effect is characterized by decreases in the discharge voltage curve with operational life and cycling. The end effect of reconditioning NiH2 cells may be hidden in the versatility, of that design over the NiCd cell design and its associated negative electrode fading problem. The process of deep discharge at lower rates by way of reconditioning tends to redistribute electrolyte and water in the NiH2 cell electrode stack, while improving utilization and charge efficiency. NiH2 battery reconditioning effects on life are considered beneficial and may, in fact. extend life based on NiCd experience. In any case, usable capacity data obtained from reconditioning is required for performance evaluation and trend analysis. Characterization and life tests have provided the historical data base used to

Raising a Child in the Punana Leo: Everyone (Men and Women) Play an Important Role

ERIC Educational Resources Information Center

Iokepa-Guerrero, Noelani

2008-01-01

Established in 1983 by a group of parents and teachers, the 'Aha Punana Leo ('APL) was formed. A grassroots organization, 'APL was established to respond to the dismal plight of the Hawaiian language. Just a mere 25 years ago, the Hawaiian language was on the verge of being lost forever. Through the dedicated efforts of a small group of friends…

Widefield fluorescence sectioning with HiLo microscopy.

PubMed

Mertz, Jerome; Lim, Daryl; Chu, Kengyeh K; Bozinovic, Nenad; Ford, Timothy

2009-01-01

HiLo microscopy is a widefield fluorescence imaging technique that provides depth discrimination by combining two images, one with non-uniform illumination and one with uniform illumination. We discuss the theory of this technique and a variety of practical implementations in brain-tissue imaging and fluorescence endomicroscopy.

Technology Development for Human Exploration Beyond LEO in the New Millennium IAA-13-3 Strategies and Plans for Human Mars Missions

NASA Technical Reports Server (NTRS)

Larson, William E.; Lueck, Dale E.; Parrish, Clyde F.; Sanders, Gerald B.; Trevathan, Joseph R.; Baird, R. Scott; Simon, Tom; Peters, T.; Delgado, H. (Technical Monitor)

2001-01-01

As we look forward into the new millennium, the extension of human presence beyond Low-Earth Orbit (LEO) looms large in the plans of NASA. The Agency's Strategic Plan specifically calls out the need to identify and develop technologies for 100 and 1000-day class missions beyond LEO. To meet the challenge of these extended duration missions, it is important that we learn how to utilize the indigenous resources available to us on extraterrestrial bodies. This concept, known as In-Situ Resource Utilization (ISRU) can greatly reduce the launch mass & cost of human missions while reducing the risk. These technologies may also pave the way for the commercial development of space. While no specific target beyond LEO is identified in NASA's Strategic Plan, mission architecture studies have been on-going for the Moon, Mars, Near-Earth Asteroids and Earth/Moon & Earth/Sun Libration Points. As a result of these studies, the NASA Office of Space Flight (Code M) through the Johnson and Kennedy Space Centers, is leading the effort to develop ISRU technologies and systems to meet the current and future needs of human missions beyond LEO and on to Mars. This effort also receives support from the NASA Office of Biological and Physical Research (Code U), the Office of Space Science (Code S), and the Office of Aerospace Technology (Code R). This paper will present unique developments in the area of fuel and oxidizer production, breathing air production, water production, C02 collection, separation of atmospheric gases, and gas liquefaction and storage. A technology overview will be provided for each topic along with the results achieved to date, future development plans, and the mission architectures that these technologies support.

Fast optically sectioned fluorescence HiLo endomicroscopy.

PubMed

Ford, Tim N; Lim, Daryl; Mertz, Jerome

2012-02-01

We describe a nonscanning, fiber bundle endomicroscope that performs optically sectioned fluorescence imaging with fast frame rates and real-time processing. Our sectioning technique is based on HiLo imaging, wherein two widefield images are acquired under uniform and structured illumination and numerically processed to reject out-of-focus background. This work is an improvement upon an earlier demonstration of widefield optical sectioning through a flexible fiber bundle. The improved device features lateral and axial resolutions of 2.6 and 17 μm, respectively, a net frame rate of 9.5 Hz obtained by real-time image processing with a graphics processing unit (GPU) and significantly reduced motion artifacts obtained by the use of a double-shutter camera. We demonstrate the performance of our system with optically sectioned images and videos of a fluorescently labeled chorioallantoic membrane (CAM) in the developing G. gallus embryo. HiLo endomicroscopy is a candidate technique for low-cost, high-speed clinical optical biopsies.

Fast optically sectioned fluorescence HiLo endomicroscopy

NASA Astrophysics Data System (ADS)

Ford, Tim N.; Lim, Daryl; Mertz, Jerome

2012-02-01

We describe a nonscanning, fiber bundle endomicroscope that performs optically sectioned fluorescence imaging with fast frame rates and real-time processing. Our sectioning technique is based on HiLo imaging, wherein two widefield images are acquired under uniform and structured illumination and numerically processed to reject out-of-focus background. This work is an improvement upon an earlier demonstration of widefield optical sectioning through a flexible fiber bundle. The improved device features lateral and axial resolutions of 2.6 and 17 μm, respectively, a net frame rate of 9.5 Hz obtained by real-time image processing with a graphics processing unit (GPU) and significantly reduced motion artifacts obtained by the use of a double-shutter camera. We demonstrate the performance of our system with optically sectioned images and videos of a fluorescently labeled chorioallantoic membrane (CAM) in the developing G. gallus embryo. HiLo endomicroscopy is a candidate technique for low-cost, high-speed clinical optical biopsies.

Fast optically sectioned fluorescence HiLo endomicroscopy

PubMed Central

Lim, Daryl; Mertz, Jerome

2012-01-01

Abstract. We describe a nonscanning, fiber bundle endomicroscope that performs optically sectioned fluorescence imaging with fast frame rates and real-time processing. Our sectioning technique is based on HiLo imaging, wherein two widefield images are acquired under uniform and structured illumination and numerically processed to reject out-of-focus background. This work is an improvement upon an earlier demonstration of widefield optical sectioning through a flexible fiber bundle. The improved device features lateral and axial resolutions of 2.6 and 17 μm, respectively, a net frame rate of 9.5 Hz obtained by real-time image processing with a graphics processing unit (GPU) and significantly reduced motion artifacts obtained by the use of a double-shutter camera. We demonstrate the performance of our system with optically sectioned images and videos of a fluorescently labeled chorioallantoic membrane (CAM) in the developing G. gallus embryo. HiLo endomicroscopy is a candidate technique for low-cost, high-speed clinical optical biopsies. PMID:22463023

Higgs boson gluon-fusion production beyond threshold in N 3LO QCD

DOE PAGES

Anastasiou, Charalampos; Duhr, Claude; Dulat, Falko; ...

2015-03-18

In this study, we compute the gluon fusion Higgs boson cross-section at N 3LO through the second term in the threshold expansion. This calculation constitutes a major milestone towards the full N 3LO cross section. Our result has the best formal accuracy in the threshold expansion currently available, and includes contributions from collinear regions besides subleading corrections from soft and hard regions, as well as certain logarithmically enhanced contributions for general kinematics. We use our results to perform a critical appraisal of the validity of the threshold approximation at N 3LO in perturbative QCD.

Particle flows to shape and voltage surface discontinuities in the electron sheath surrounding a high voltage solar array in LEO

NASA Technical Reports Server (NTRS)

Metz, Roger N.

1991-01-01

This paper discusses the numerical modeling of electron flows from the sheath surrounding high positively biased objects in LEO (Low Earth Orbit) to regions of voltage or shape discontinuity on the biased surfaces. The sheath equations are derived from the Two-fluid, Warm Plasma Model. An equipotential corner and a plane containing strips of alternating voltage bias are treated in two dimensions. A self-consistent field solution of the sheath equations is outlined and is pursued through one cycle. The electron density field is determined by numerical solution of Poisson's equation for the electrostatic potential in the sheath using the NASCAP-LEO relation between electrostatic potential and charge density. Electron flows are calculated numerically from the electron continuity equation. Magnetic field effects are not treated.

Data analysis and interpretation related to space system/environment interactions at LEO altitude

NASA Technical Reports Server (NTRS)

Raitt, W. John; Schunk, Robert W.

1991-01-01

Several studies made on the interaction of active systems with the LEO space environment experienced from orbital or suborbital platforms are covered. The issue of high voltage space interaction is covered by theoretical modeling studies of the interaction of charged solar cell arrays with the ionospheric plasma. The theoretical studies were complemented by experimental measurements made in a vacuum chamber. The other active system studied was the emission of effluent from a space platform. In one study the emission of plasma into the LEO environment was studied by using initially a 2-D model, and then extending this model to 3-D to correctly take account of plasma motion parallel to the geomagnetic field. The other effluent studies related to the releases of neutral gas from an orbiting platform. One model which was extended and used determined the density, velocity, and energy of both an effluent gas and the ambient upper atmospheric gases over a large volume around the platform. This model was adapted to study both ambient and contaminant distributions around smaller objects in the orbital frame of reference with scale sizes of 1 m. The other effluent studies related to the interaction of the released neutral gas with the ambient ionospheric plasma. An electrostatic model was used to help understand anomalously high plasma densities measured at times in the vicinity of the space shuttle orbiter.

Effects of space weather on the ionosphere and LEO satellites' orbital trajectory in equatorial, low and middle latitude

NASA Astrophysics Data System (ADS)

Nwankwo, Victor U. J.; Chakrabarti, Sandip K.

2018-04-01

We study the effects of space weather on the ionosphere and low Earth orbit (LEO) satellites' orbital trajectory in equatorial, low- and mid-latitude (EQL, LLT and MLT) regions during (and around) the notable storms of October/November, 2003. We briefly review space weather effects on the thermosphere and ionosphere to demonstrate that such effects are also latitude-dependent and well established. Following the review we simulate the trend in variation of satellite's orbital radius (r), mean height (h) and orbit decay rate (ODR) during 15 October-14 November 2003 in EQL, LLT and MLT. Nominal atmospheric drag on LEO satellite is usually enhanced by space weather or solar-induced variations in thermospheric temperature and density profile. To separate nominal orbit decay from solar-induced accelerated orbit decay, we compute r, h and ODR in three regimes viz. (i) excluding solar indices (or effect), where r =r0, h =h0 and ODR =ODR0 (ii) with mean value of solar indices for the interval, where r =rm, h =hm and ODR =ODRm and (iii) with actual daily values of solar indices for the interval (r, h and ODR). For a typical LEO satellite at h = 450 km, we show that the total decay in r during the period is about 4.20 km, 3.90 km and 3.20 km in EQL, LLT and MLT respectively; the respective nominal decay (r0) is 0.40 km, 0.34 km and 0.22 km, while solar-induced orbital decay (rm) is about 3.80 km, 3.55 km and 2.95 km. h also varied in like manner. The respective nominal ODR0 is about 13.5 m/day, 11.2 m/day and 7.2 m/day, while solar-induced ODRm is about 124.3 m/day, 116.9 m/day and 97.3 m/day. We also show that severe geomagnetic storms can increase ODR by up to 117% (from daily mean value). However, the extent of space weather effects on LEO Satellite's trajectory significantly depends on the ballistic co-efficient and orbit of the satellite, and phase of solar cycles, intensity and duration of driving (or influencing) solar event.

Enhancing LoRaWAN Security through a Lightweight and Authenticated Key Management Approach.

PubMed

Sanchez-Iborra, Ramon; Sánchez-Gómez, Jesús; Pérez, Salvador; Fernández, Pedro J; Santa, José; Hernández-Ramos, José L; Skarmeta, Antonio F

2018-06-05

Luckily, new communication technologies and protocols are nowadays designed considering security issues. A clear example of this can be found in the Internet of Things (IoT) field, a quite recent area where communication technologies such as ZigBee or IPv6 over Low power Wireless Personal Area Networks (6LoWPAN) already include security features to guarantee authentication, confidentiality and integrity. More recent technologies are Low-Power Wide-Area Networks (LP-WAN), which also consider security, but present initial approaches that can be further improved. An example of this can be found in Long Range (LoRa) and its layer-two supporter LoRa Wide Area Network (LoRaWAN), which include a security scheme based on pre-shared cryptographic material lacking flexibility when a key update is necessary. Because of this, in this work, we evaluate the security vulnerabilities of LoRaWAN in the area of key management and propose different alternative schemes. Concretely, the application of an approach based on the recently specified Ephemeral Diffie⁻Hellman Over COSE (EDHOC) is found as a convenient solution, given its flexibility in the update of session keys, its low computational cost and the limited message exchanges needed. A comparative conceptual analysis considering the overhead of different security schemes for LoRaWAN is carried out in order to evaluate their benefits in the challenging area of LP-WAN.

Quadrature mixture LO suppression via DSW DAC noise dither

DOEpatents

Dubbert, Dale F [Cedar Crest, NM; Dudley, Peter A [Albuquerque, NM

2007-08-21

A Quadrature Error Corrected Digital Waveform Synthesizer (QECDWS) employs frequency dependent phase error corrections to, in effect, pre-distort the phase characteristic of the chirp to compensate for the frequency dependent phase nonlinearity of the RF and microwave subsystem. In addition, the QECDWS can employ frequency dependent correction vectors to the quadrature amplitude and phase of the synthesized output. The quadrature corrections cancel the radars' quadrature upconverter (mixer) errors to null the unwanted spectral image. A result is the direct generation of an RF waveform, which has a theoretical chirp bandwidth equal to the QECDWS clock frequency (1 to 1.2 GHz) with the high Spurious Free Dynamic Range (SFDR) necessary for high dynamic range radar systems such as SAR. To correct for the problematic upconverter local oscillator (LO) leakage, precision DC offsets can be applied over the chirped pulse using a pseudo-random noise dither. The present dither technique can effectively produce a quadrature DC bias which has the precision required to adequately suppress the LO leakage. A calibration technique can be employed to calculate both the quadrature correction vectors and the LO-nulling DC offsets using the radar built-in test capability.

High intensity 5 eV atomic oxygen source and Low Earth Orbit (LEO) simulation facility

NASA Technical Reports Server (NTRS)

Cross, J. B.; Spangler, L. H.; Hoffbauer, M. A.; Archuleta, F. A.; Leger, Lubert; Visentine, James

1987-01-01

An atomic oxygen exposure facility has been developed for studies of material degradation. The goal of these studies is to provide design criteria and information for the manufacture of long life (20 to 30 years) construction materials for use in LEO. The studies that are being undertaken using the facility will provide: absolute reaction cross sections for use in engineering design problems; formulations of reaction mechanisms; and calibration of flight hardware (mass spectrometers, etc.) in order to directly relate experiments performed in LEO to ground based investigations. The facility consists of: (1) a CW laser sustained discharge source of O atoms having a variable energy up to 5 eV and an intensity between 10(15) and 10(17) O atoms s(-1) cm(-2); (2) an atomic beam formation and diagnostics system consisting of various stages of differential pumping, a mass spectrometer detector, and a time of flight analyzer; (3) a spinning rotor viscometer for absolute O atom flux measurements; and (4) provision for using the system for calibration of actual flight instruments. Surface analysis equipment is available for the characterization of material surfaces before and after exposure to O atoms.

LEO-to-ground polarization measurements aiming for space QKD using Small Optical TrAnsponder (SOTA).

PubMed

Carrasco-Casado, Alberto; Kunimori, Hiroo; Takenaka, Hideki; Kubo-Oka, Toshihiro; Akioka, Maki; Fuse, Tetsuharu; Koyama, Yoshisada; Kolev, Dimitar; Munemasa, Yasushi; Toyoshima, Morio

2016-05-30

Quantum communication, and more specifically Quantum Key Distribution (QKD), enables the transmission of information in a theoretically secure way, guaranteed by the laws of quantum physics. Although fiber-based QKD has been readily available since several years ago, a global quantum communication network will require the development of space links, which remains to be demonstrated. NICT launched a LEO satellite in 2014 carrying a lasercom terminal (SOTA), designed for in-orbit technological demonstrations. In this paper, we present the results of the campaign to measure the polarization characteristics of the SOTA laser sources after propagating from LEO to ground. The most-widely used property for encoding information in free-space QKD is the polarization, and especially the linear polarization. Therefore, studying its behavior in a realistic link is a fundamental step for proving the feasibility of space quantum communications. The results of the polarization preservation of two highly-polarized lasers are presented here, including the first-time measurement of a linearly-polarized source at λ = 976 nm and a circularly-polarized source at λ = 1549 nm from space using a realistic QKD-like receiver, installed in the Optical Ground Station at the NICT Headquarters, in Tokyo, Japan.

Co-expression of COX-2 and 5-LO in primary glioblastoma is associated with poor prognosis.

PubMed

Wang, Xingfu; Chen, Yupeng; Zhang, Sheng; Zhang, Lifeng; Liu, Xueyong; Zhang, Li; Li, Xiaoling; Chen, Dayang

2015-11-01

Cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LO) are important factors in tumorigenesis and malignant progression; however, studies of their roles in glioblastoma have produced conflicting results. To define the frequencies of COX-2 and 5-LO expression and their correlation with clinicopathological features and prognosis, tumor tissues from 76 cases of newly diagnosed primary ordinary glioblastoma were examined for COX-2 and 5-LO expression by immunohistochemistry. The expression levels of COX-2 and 5-LO and the relationships between the co-expression of COX-2/5-LO and patient age and gender, edema index (EI), Karnofsky Performance Scale and overall survival (OS) were analyzed. COX-2 and 5-LO were expressed in 73.7 % (56/76) and 92.1 % (70/76) of the samples, respectively. Among the clinicopathological characteristics, only age (>60 years) exhibited a significant association with the high expression of COX-2. No statistically significant correlations were found in the 5-LO cohort. A significant positive correlation was revealed between the COX-2 and 5-LO scores (r = 0.374; p = 0.001). The elevated co-expression of COX-2 and 5-LO was observed primarily in the patients over the age of 60 years. Patients with a high expression of COX-2 had a significantly shorter OS (p < 0.01), whereas the immunoexpression of 5-LO was not associated with the OS of patients with glioblastoma. Survival analysis indicated that simultaneous high levels of COX-2 and 5-LO expression were significantly correlated with poor OS and, conversely, that a low/low expression pattern of these two proteins was significantly associated with better OS (p < 0.05). Moreover, the Cox multivariable proportional hazard model showed that a high expression of COX-2, high co-expression of COX-2 and 5-LO, and a high Ki-67 index were significant predictors of shorter OS in primary glioblastoma, independent of age, gender, EI, 5-LO expression and p53 status. The hazard ratios for OS were 2.347 (95 % CI 1

20 CFR 10.735 - When is a non-Federal law enforcement officer (LEO) covered under the FECA?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 20 Employees' Benefits 1 2011-04-01 2011-04-01 false When is a non-Federal law enforcement officer... EMPLOYEES' COMPENSATION ACT, AS AMENDED Special Provisions Non-Federal Law Enforcement Officers § 10.735 When is a non-Federal law enforcement officer (LEO) covered under the FECA? (a) A law enforcement...

20 CFR 10.735 - When is a non-Federal law enforcement officer (LEO) covered under the FECA?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 20 Employees' Benefits 1 2013-04-01 2012-04-01 true When is a non-Federal law enforcement officer... EMPLOYEES' COMPENSATION ACT, AS AMENDED Special Provisions Non-Federal Law Enforcement Officers § 10.735 When is a non-Federal law enforcement officer (LEO) covered under the FECA? (a) A law enforcement...

20 CFR 10.735 - When is a non-Federal law enforcement officer (LEO) covered under the FECA?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 20 Employees' Benefits 1 2014-04-01 2012-04-01 true When is a non-Federal law enforcement officer... EMPLOYEES' COMPENSATION ACT, AS AMENDED Special Provisions Non-Federal Law Enforcement Officers § 10.735 When is a non-Federal law enforcement officer (LEO) covered under the FECA? (a) A law enforcement...

20 CFR 10.735 - When is a non-Federal law enforcement officer (LEO) covered under the FECA?

Code of Federal Regulations, 2012 CFR

2012-04-01

... 20 Employees' Benefits 1 2012-04-01 2012-04-01 false When is a non-Federal law enforcement officer... EMPLOYEES' COMPENSATION ACT, AS AMENDED Special Provisions Non-Federal Law Enforcement Officers § 10.735 When is a non-Federal law enforcement officer (LEO) covered under the FECA? (a) A law enforcement...

20 CFR 10.735 - When is a non-Federal law enforcement officer (LEO) covered under the FECA?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false When is a non-Federal law enforcement officer... EMPLOYEES' COMPENSATION ACT, AS AMENDED Special Provisions Non-Federal Law Enforcement Officers § 10.735 When is a non-Federal law enforcement officer (LEO) covered under the FECA? (a) A law enforcement...

LoCoH: Non-parameteric kernel methods for constructing home ranges and utilization distributions

USGS Publications Warehouse

Getz, Wayne M.; Fortmann-Roe, Scott; Cross, Paul C.; Lyons, Andrew J.; Ryan, Sadie J.; Wilmers, Christopher C.

2007-01-01

Parametric kernel methods currently dominate the literature regarding the construction of animal home ranges (HRs) and utilization distributions (UDs). These methods frequently fail to capture the kinds of hard boundaries common to many natural systems. Recently a local convex hull (LoCoH) nonparametric kernel method, which generalizes the minimum convex polygon (MCP) method, was shown to be more appropriate than parametric kernel methods for constructing HRs and UDs, because of its ability to identify hard boundaries (e.g., rivers, cliff edges) and convergence to the true distribution as sample size increases. Here we extend the LoCoH in two ways: ‘‘fixed sphere-of-influence,’’ or r -LoCoH (kernels constructed from all points within a fixed radius r of each reference point), and an ‘‘adaptive sphere-of-influence,’’ or a -LoCoH (kernels constructed from all points within a radius a such that the distances of all points within the radius to the reference point sum to a value less than or equal to a ), and compare them to the original ‘‘fixed-number-of-points,’’ or k -LoCoH (all kernels constructed from k -1 nearest neighbors of root points). We also compare these nonparametric LoCoH to parametric kernel methods using manufactured data and data collected from GPS collars on African buffalo in the Kruger National Park, South Africa. Our results demonstrate that LoCoH methods are superior to parametric kernel methods in estimating areas used by animals, excluding unused areas (holes) and, generally, in constructing UDs and HRs arising from the movement of animals influenced by hard boundaries and irregular structures (e.g., rocky outcrops). We also demonstrate that a -LoCoH is generally superior to k - and r -LoCoH (with software for all three methods available at http://locoh.cnr.berkeley.edu).

LEGEND, a LEO-to-GEO Environment Debris Model

NASA Technical Reports Server (NTRS)

Liou, Jer Chyi; Hall, Doyle T.

2013-01-01

LEGEND (LEO-to-GEO Environment Debris model) is a three-dimensional orbital debris evolutionary model that is capable of simulating the historical and future debris populations in the near-Earth environment. The historical component in LEGEND adopts a deterministic approach to mimic the known historical populations. Launched rocket bodies, spacecraft, and mission-related debris (rings, bolts, etc.) are added to the simulated environment. Known historical breakup events are reproduced, and fragments down to 1 mm in size are created. The LEGEND future projection component adopts a Monte Carlo approach and uses an innovative pair-wise collision probability evaluation algorithm to simulate the future breakups and the growth of the debris populations. This algorithm is based on a new "random sampling in time" approach that preserves characteristics of the traditional approach and captures the rapidly changing nature of the orbital debris environment. LEGEND is a Fortran 90-based numerical simulation program. It operates in a UNIX/Linux environment.

Arcing in LEO: Does the Whole Array Discharge?

NASA Technical Reports Server (NTRS)

Ferguson, Dale C.; Vayner, Boris V.; Galofaro, Joel T.; Hillard, G. Barry

2005-01-01

The conventional wisdom about solar array arcing in LEO is that only the parts of the solar array that are swept over by the arc-generated plasma front are discharged in the initial arc. This limits the amount of energy that can be discharged. Recent work done at the NASA Glenn Research Center has shown that this idea is mistaken. In fact, the capacitance of the entire solar array may be discharged, which for large arrays leads to very large and possibly debilitating arcs, even if no sustained arc occurs. We present the laboratory work that conclusively demonstrates this fact by using a grounded plate that prevents the arc-plasma front from reaching certain array strings. Finally, we discuss the dependence of arc strength and arc pulse width on the capacitance that is discharged, and provide a physical mechanism for discharge of the entire array, even when parts of the array are not accessible to the arc-plasma front. Mitigation techniques are also presented.

The 15-LO-1/15-HETE system promotes angiogenesis by upregulating VEGF in ischemic brains.

PubMed

Chen, Li; Zhu, Yan-Mei; Li, Yu-Nong; Li, Peng-Yan; Wang, Di; Liu, Yu; Qu, You-Yang; Zhu, Da-Ling; Zhu, Yu-Lan

2017-09-01

Angiogenesis promotes neurobehavioral recovery after cerebral ischemic stroke. 15(S)-hydroxyeicosatetraenoic acid (15-HETE) is one of the major metabolites of arachidonic acid by 15-lipoxygenase (15-LO) and stimulates the production of vascular endothelial growth factor (VEGF), thus, inducing autocrine-mediated angiogenesis. The present study aimed to investigate the role of 15-LO/15-HETE system on VEGF expression and angiogenesis in brain ischemia. Rat cerebral arterial vascular endothelial cells were used to set up a cell injury model of oxygen-glucose deprivation and reoxygenation (OGD/R), mimicking a condition of brain ischemia. A mouse model of middle cerebral artery occlusion (MCAO) was established. Oxygen-glucose deprivation increased cellular expression of 15-LO-1 and VEGF. Transfection of 15-LO-1 siRNA depleted cells of 15-LO-1, and sequentially induced downregulation of VEGF expression; while, incubation of 15-HETE increased the expression of VEGF. Incubation of 15-HETE attenuated the reduction in cell viability induced by oxygen-glucose deprivation, and promoted cell migration, while transfection of 15-LO-1 siRNA showed an opposite effect. In animal experiments, the density of microvessels in hypoxic regions of brains was significantly increased after MCAO, while intracerebroventricular delivery of 15-LO-1 siRNA significantly reduced the density of microvessels, and downregulates VEGF expression. The results indicate that the 15-LO-1/15-HETE system promotes angiogenesis in ischemic brains by upregulation of VEGF, representing a potential target for improving neurobehavioral recovery after cerebral ischemic stroke.

Keystone Life Orientation (LO) Teachers: Implications for Educational, Social, and Cultural Contexts

ERIC Educational Resources Information Center

Pillay, Jace

2012-01-01

The aim of this study was to identify and describe skills, characteristics and support networks needed by keystone Life Orientation (LO) teachers in six Gauteng schools. In this study "keystone" refers to LO teachers who make a positive impact in their schools. A qualitative research design was used to collect data through interviews,…

A Sensitivity Study on the Effectiveness of Active Debris Removal in LEO

NASA Technical Reports Server (NTRS)

Liou, J. C.; Johnson, Nicholas L.

2007-01-01

The near-Earth orbital debris population will continue to increase in the future due to ongoing space activities, on-orbit explosions, and accidental collisions among resident space objects. Commonly adopted mitigation measures, such as limiting postmission orbital lifetimes of satellites to less than 25 years, will slow down the population growth, but may be insufficient to stabilize the environment. The nature of the growth, in the low Earth orbit (LEO) region, is further demonstrated by a recent study where no future space launches were conducted in the environment projection simulations. The results indicate that, even with no new launches, the LEO debris population would remain relatively constant for only the next 50 years. Beyond that, the debris population would begin to increase noticeably, due to the production of collisional debris. Therefore, to better limit the growth of future debris population to protect the environment, remediation option, i.e., removing existing large and massive objects from orbit, needs to be considered. This paper does not intend to address the technical or economical issues for active debris removal. Rather, the objective is to provide a sensitivity study to quantify the effectiveness of various remediation options. A removal criterion based upon mass and collision probability is developed to rank objects at the beginning of each projection year. This study includes simulations with removal rates ranging from 2 to 20 objects per year, starting in the year 2020. The outcome of each simulation is analyzed, and compared with others. The summary of the study serves as a general guideline for future debris removal consideration.

A Simultaneous Discovery: The Case of Johannes Stark and Antonino Lo Surdo

NASA Astrophysics Data System (ADS)

Leone, Matteo; Paoletti, Alessandro; Robotti, Nadia

2004-09-01

In 1913 the German physicist Johannes Stark (1874 1957) and the Italian physicist Antonino Lo Surdo (1880 1949)discovered virtually simultaneously and independently that hydrogen spectral lines are split into components by an external electric field. Both of their discoveries ensued from studies on the same phenomenon, the Doppler effect in canal rays, but they arose in different theoretical contexts. Stark had been working within the context of the emerging quantum theory, following a research program aimed at studying the effect of an electric field on spectral lines. Lo Surdo had been working within the context of the classical theory, and his was an accidental discovery. Both discoveries, however, played important roles in the history of physics: Stark’s discovery contributed to the establishment of both the old and the new quantum theories; Lo Surdo’s discovery led Antonio Garbasso (1871 1933)to introduce research on the quantum theory into Italian physics. Ironically, soon after their discoveries, both Stark and Lo Surdo rejected developments in modern physics and allied themselves with the political and racial programs of Hitler and Mussolini.

Treatment of malignant lymphoma in an African lion (Panthera leo).

PubMed

Harrison, Tara M; Sikarskie, James; Kitchell, Barbara; Rosenstein, Diana S; Flaherty, Heather; Fitzgerald, Scott D; Kiupel, Matti

2007-06-01

A 14 yr-old male, vasectomized African lion (Panthera leo) exhibited mild weight loss despite adequate appetite. Splenomegaly was diagnosed on physical examination. On the basis of hematology and clinical pathology, malignant lymphoma with chronic lymphocytic leukemia was diagnosed. Abdominal exploratory surgery and splenectomy were performed. Histologic examination and immunohistochemistry confirmed a small cell peripheral T-cell lymphoma. Initial treatments consisted of doxorubicin and prednisone, with later addition of lomustine. The lion remained in clinical remission at 2 mo, 6 mo, and 12 mo postchemotherapy physical examinations. The lion survived 504 days from initial diagnosis. At necropsy, the only lesions consistent with lymphoma were localized epitheliotrophic infiltrates of small neoplastic T lymphocytes within the nasopharyngeal epithelium and the underlying submucosa observed on microscopic examination.

Next Generation Grating Spectrometer Sounders for LEO and GEO

NASA Technical Reports Server (NTRS)

Pagano, Thomas S.

2011-01-01

AIRS and MODIS are widely used for weather, climate, composition, carbon cycle, cross-calibration, and applications. The community asking for new capability in the 2020 timeframe, capabilities desired: (1) Hyperspectral UV to LWIR, High Spatial ?1km IFOV (2) Maximize Synergies of Solar Reflected and IR. Synergies with OCO-2. We expect more users and applications of next gen LEO IR Sounder than GEO. These include: weather, climate, GHG monitoring, aviation, disaster response. There is a new direction for imagers and sounders: (1) Separate Vis/NIR/SWIR from MWIR/LWIR instruments reduces technology risk and complexity. (2) Expect Costs to be lower than CrIS & VIIRS Some additional ideas to reduce costs include: (1) minimum set of requirements (2) mini-grating spectrometers. supports constellation for higher revisit (3) new technology to reduce instrument size (large format fpa's) (4) hosted payloads

Inhibition of 12/15-LO ameliorates CVB3-induced myocarditis by activating Nrf2.

PubMed

Ai, Feng; Zheng, Jiayong; Zhang, Yanwei; Fan, Taibing

2017-06-25

Cardiac 12/15-lipoxygenase (12/15-LO) was reported to be markedly up-regulated and involved in the development of heart failure. Nuclear factor E2-related factor 2 (Nrf2) plays anti-inflammatory and anti-oxidation roles in response to oxidative stress. However, the role of 12/15-LO in viral myocarditis (VMC) and its underlying molecular mechanism have not yet been elucidated. Here, we demonstrated that 12/15-LO was up-regulated and Nrf2 was down-regulated in coxsackievirus B3 (CVB3)-infected mice and cardiac myocytes. Baicalein, the specific inhibitor of 12/15-LO, was employed to investigate the role of 12/15-LO and its underlying mechanism in VMC. We found that baicalein treatment alleviated CVB3-induced VMC mouse models, as demonstrated by less inflammatory lesions in the heart tissues and less CK-MB level. Moreover, baicalein treatment attenuated CVB3-induced inflammatory cytokine production and oxidative stress. Mechanistic analysis suggested that baicalein treatment relieved CVB3-induced reduction of Nrf2 and heme oxygenase-1 (HO-1) expressions. Taken together, our study indicated that inhibition of 12/15-LO ameliorates VMC by activating Nrf2, providing a new therapeutic strategy for the therapy of VMC. Copyright © 2017 Elsevier B.V. All rights reserved.

Differential Higgs production at N3LO beyond threshold

NASA Astrophysics Data System (ADS)

Dulat, Falko; Mistlberger, Bernhard; Pelloni, Andrea

2018-01-01

We present several key steps towards the computation of differential Higgs boson cross sections at N3LO in perturbative QCD. Specifically, we work in the framework of Higgs-differential cross sections that allows to compute precise predictions for realistic LHC observables. We demonstrate how to perform an expansion of the analytic N3LO coefficient functions around the production threshold of the Higgs boson. Our framework allows us to compute to arbitrarily high order in the threshold expansion and we explicitly obtain the first two expansion coefficients in analytic form. Furthermore, we assess the phenomenological viability of threshold expansions for differential distributions. We find that while a few terms in the threshold expansion are sufficient to approximate the exact rapidity distribution well, transverse momentum distributions require a signficantly higher number of terms in the expansion to be adequately described. We find that to improve state of the art predictions for the rapidity distribution beyond NNLO even more sub-leading terms in the threshold expansion than presented in this article are required. In addition, we report on an interesting obstacle for the computation of N3LO corrections with LHAPDF parton distribution functions and our solution. We provide files containing the analytic expressions for the partonic cross sections as supplementary material attached to this paper.

Resonant tunnelling diode oscillator as an alternative LO for SIS receiver applications

NASA Technical Reports Server (NTRS)

Blundell, R.; Papa, D. C.; Brown, E. R.; Parker, C. D.

1993-01-01

The resonant tunnelling diode (RTD) oscillator has been demonstrated for the first time as a local oscillator (LO) in a heterodyne receiver. Noise measurements made on a sensitive 200 GHz superconductor-insulator-superconductor receiver using both a multiplied Gunn diode and an RTD oscillator as the LO revealed no difference in receiver noise as a function of oscillator type.

Integrating Archaeological Modeling in DoD Cultural Resource Compliance

DTIC Science & Technology

2012-10-26

Leo 2001 Random Forests. Machine Learning 45:5–32. Briuer, Frederick, Clifford Brown, Alan Gillespie, Fredrick Limp, Michael Trimble, and Len...glaciolacustrine clays on glacial lake plains Inceptisols Very-fine, mixed, active, nonacid, mesic Mollic Endoaquepts Low to none LoC Lowville silt

The CEA-/lo colorectal cancer cell population harbors cancer stem cells and metastatic cells.

PubMed

Yan, Chang; Hu, Yibing; Zhang, Bo; Mu, Lei; Huang, Kaiyu; Zhao, Hui; Ma, Chensen; Li, Xiaolan; Tao, Deding; Gong, Jianping; Qin, Jichao

2016-12-06

Serum carcinoembryonic antigen (CEA) is the most commonly used tumor marker in a variety of cancers including colorectal cancer (CRC) for tumor diagnosis and monitoring. Recent studies have shown that colonic crypt cells expressing little or no CEA may enrich for stem cells. Numerous studies have clearly shown that there exist CRC patients with normal serum CEA levels during tumor progression or even tumor relapse, although CEA itself is considered to promote metastasis and block cell differentiation. These seemingly contradictory observations prompted us to investigate, herein, the biological properties as well as tumorigenic and metastatic capacity of CRC cells that express high (CEA+) versus low CEA (CEA-/lo) levels of CEA. Our findings show that the abundance of CEA-/lo cells correlate with poor differentiation and poor prognosis, and moreover, CEA-/lo cells form more spheres in vitro, generate more tumors and exhibit a higher potential in developing liver and lung metastases than corresponding CEA+ cells. Applying RNAi-mediated approach, we found that IGF1R mediated tumorigenic and capacity of CEA-/lo cells but did not mediate those of CEA+ cells. Notably, our data demonstrated that CEA molecule was capable of protecting CEA-/lo cells from anoikis, implying that CEA+ cells, although themselves possessing less tumorigenic and metastatic capacity, may promote metastasis of CEA-/lo cells via secreting CEA molecule. Our observations suggest that, besides targeting CEA molecule, CEA-/lo cells may represent a critical source of tumor progression and metastasis, and should therefore be the target of future therapies.

The Star Formation History of the Local Group Dwarf Galaxy Leo I

NASA Astrophysics Data System (ADS)

Gallart, Carme; Freedman, Wendy L.; Aparicio, Antonio; Bertelli, Giampaolo; Chiosi, Cesare

1999-11-01

We present a quantitative analysis of the star formation history (SFH) of the Local Group dSph galaxy Leo I, from the information in its Hubble Space Telescope [(V-I),I] color-magnitude diagram (CMD). It reaches the level of the oldest main-sequence turnoffs, and this allows us to retrieve the SFH in considerable detail. The method we use is based on comparing, via synthetic CMDs, the expected distribution of stars in the CMD for different evolutionary scenarios with the observed distribution. We consider the SFH to be composed by the SFR(t), the chemical enrichment law Z(t), the initial mass function (IMF), and a function β(f,q) controlling the fraction f and mass ratio distribution q of binary stars. We analyze a set of ~=50 combinations of four Z(t), three IMFs, and more than four β(f,q). For each of them, the best SFR(t) is searched for among ~=6x107 models. The comparison between the observed CMD and the model CMDs is done through χ2ν minimization of the differences in the number of stars in a set of regions of the CMD, chosen to sample stars of different ages or in specific stellar evolutionary phases. We empirically determine the range of χ2ν values that indicate acceptable models for our set of data using tests with models with known SFHs. Our solution for the SFH of Leo I defines a minimum of χ2ν in a well-defined position of the parameter space, and the derived SFR(t) is robust, in the sense that its main characteristics are unchanged for different combinations of the remaining parameters. However, only a narrow range of assumptions for Z(t), IMF, and β(f,q) result in a good agreement between the data and the models, namely, Z=0.0004, a IMF Kroupa et al. or slightly steeper, and a relatively large fraction of binary stars, with f=0.3-0.6, q>0.6, and an approximately flat IMF for the secondaries, or particular combinations of these parameters that would produce a like fraction of similar mass binaries. Most star formation activity (70% to 80

Effect of Propellant Flowrate and Purity on Carbon Deposition in LO2/Methane Gas Generators

NASA Technical Reports Server (NTRS)

Bossard, J. A.; Burkhardt, W. M.; Niiya, K. Y.; Braam, F.

1989-01-01

The generation and deposition of carbon was studied in the Carbon Deposition Program using subscale hardware with LO2/Liquid Natural Gas (LNG) and LO2/Methane propellants at low mixture ratios. The purpose of the testing was to evaluate the effect of methane purity and full scale injection density on carbon deposition. The LO2/LNG gas generator/preburner testing was performed at mixture ratios between 0.24 and 0.58 and chamber pressures from 5.8 to 9.4 MPa (840 to 1370 psia). A total of seven 200 second duration tests were performed. The LNG testing occurred at low injection densities, similar to the previous LO2/RP-1, LO2/propane, and LO2/methane testing performed on the carbon deposition program. The current LO2/methane test series occurred at an injection density factor of approximately 10 times higher than the previous testing. The high injection density LO2/methane testing was performed at mixture ratios between from 0.23 to 0.81 and chamber pressures from 6.4 to 15.2 MPa (925 to 2210 psia). A total of nine high injection density tests were performed. The testing performed demonstrated that low purity methane (LNG) did not produce any detectable change in carbon deposition when compared to pure methane. In addition, the C* performance and the combustion gas temperatures measured were similar to those obtained for pure methane. Similar results were obtained testing pure methane at higher propellant injection densities with coarse injector elements.

From Leo Strauss to Collapse Theory: Considering the Neoconservative Attack on Modernity and the Work of Education

ERIC Educational Resources Information Center

Smith, David Geoffrey

2008-01-01

This paper locates the work of Leo Strauss within the broader conservative assault on modernity and especially its roots in liberalism. Four themes from Strauss's work are identified, then hermeneutically engaged for their relevance to educational practice in global times. The four themes are: (1) the liberal/modern concept of an open society is…

Modification of earth-satellite orbits using medium-energy pulsed lasers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Phipps, C.R.

1992-01-01

Laser Impulse Space Propulsion (LISP) has become an attractive concept, due to recent advances in gas laser technology, high-speed segmented mirrors and improved coeffici-ents for momentum coupling to targets in pulsed laser ablation. There are numerous specialized applications of the basic concept to space science-ranging from far-future and high capital cost to the immediate and inexpensive, such as: LEO-LISP (launch of massive objects into low-Earth-Orbit at dramatically improved cost-per-kg relative to present practice); LEGO-LISP (LEO to geosynchronous transfers); LO-LISP) (periodic re-boost of decaying LEO orbits); and LISK (geosynchronous satellite station-keeping). It is unlikely that one type of laser will bemore » best for all scenarios. In this paper, we will focus on the last two applications.« less

Modification of earth-satellite orbits using medium-energy pulsed lasers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Phipps, C.R.

1992-10-01

Laser Impulse Space Propulsion (LISP) has become an attractive concept, due to recent advances in gas laser technology, high-speed segmented mirrors and improved coeffici-ents for momentum coupling to targets in pulsed laser ablation. There are numerous specialized applications of the basic concept to space science-ranging from far-future and high capital cost to the immediate and inexpensive, such as: LEO-LISP (launch of massive objects into low-Earth-Orbit at dramatically improved cost-per-kg relative to present practice); LEGO-LISP (LEO to geosynchronous transfers); LO-LISP) (periodic re-boost of decaying LEO orbits); and LISK (geosynchronous satellite station-keeping). It is unlikely that one type of laser will bemore » best for all scenarios. In this paper, we will focus on the last two applications.« less

Frontiers in Laser Cooling, Single-Molecule Biophysics, and Enrgy Science: A Talk from Leo Holberg and Allen Mills

DOE Office of Scientific and Technical Information (OSTI.GOV)

Holberg, Leo; Mills, Allen

2008-08-30

Leo Holberg and Allen Mills present a talk at Frontiers in Laser Cooling, Single-Molecule Biophysics and Energy Science, a scientific symposium honoring Steve Chu, director of Lawrence Berkeley National Laboratory and recipient of the 1997 Nobel Prize in Physics. The symposium was held August 30, 2008 in Berkeley.

Frontiers in Laser Cooling, Single-Molecule Biophysics, and Enrgy Science: A Talk from Leo Holberg and Allen Mills

ScienceCinema

Holberg, Leo; Mills, Allen

2018-05-07

Leo Holberg and Allen Mills present a talk at Frontiers in Laser Cooling, Single-Molecule Biophysics and Energy Science, a scientific symposium honoring Steve Chu, director of Lawrence Berkeley National Laboratory and recipient of the 1997 Nobel Prize in Physics. The symposium was held August 30, 2008 in Berkeley.

Mapping the space radiation environment in LEO orbit by the SATRAM Timepix payload on board the Proba-V satellite

DOE Office of Scientific and Technical Information (OSTI.GOV)

Granja, Carlos, E-mail: carlos.granja@utef.cvut.cz; Polansky, Stepan

Detailed spatial- and time-correlated maps of the space radiation environment in Low Earth Orbit (LEO) are produced by the spacecraft payload SATRAM operating in open space on board the Proba-V satellite from the European Space Agency (ESA). Equipped with the hybrid semiconductor pixel detector Timepix, the compact radiation monitor payload provides the composition and spectral characterization of the mixed radiation field with quantum-counting and imaging dosimetry sensitivity, energetic charged particle tracking, directionality and energy loss response in wide dynamic range in terms of particle types, dose rates and particle fluxes. With a polar orbit (sun synchronous, 98° inclination) at themore » altitude of 820 km the payload samples the space radiation field at LEO covering basically the whole planet. First results of long-period data evaluation in the form of time-and spatially-correlated maps of total dose rate (all particles) are given.« less

Mapping the space radiation environment in LEO orbit by the SATRAM Timepix payload on board the Proba-V satellite

NASA Astrophysics Data System (ADS)

Granja, Carlos; Polansky, Stepan

2016-07-01

Detailed spatial- and time-correlated maps of the space radiation environment in Low Earth Orbit (LEO) are produced by the spacecraft payload SATRAM operating in open space on board the Proba-V satellite from the European Space Agency (ESA). Equipped with the hybrid semiconductor pixel detector Timepix, the compact radiation monitor payload provides the composition and spectral characterization of the mixed radiation field with quantum-counting and imaging dosimetry sensitivity, energetic charged particle tracking, directionality and energy loss response in wide dynamic range in terms of particle types, dose rates and particle fluxes. With a polar orbit (sun synchronous, 98° inclination) at the altitude of 820 km the payload samples the space radiation field at LEO covering basically the whole planet. First results of long-period data evaluation in the form of time-and spatially-correlated maps of total dose rate (all particles) are given.

Dephasing of LO-phonon-plasmon hybrid modes in n-type GaAs

NASA Astrophysics Data System (ADS)

Vallée, F.; Ganikhanov, F.; Bogani, F.

1997-11-01

The relaxation dynamics of coherent phononlike LO-phonon-plasmon hybrid modes is investigated in n-doped GaAs using an infrared time-resolved coherent anti-Stokes Raman scattering technique. Measurements performed for different crystal temperatures in the range 10-300 K as a function of the electron density injected by doping show a large reduction of the hybrid mode dephasing time compared to the bare LO-phonon one for densities larger than 1016 cm-3. The results are interpreted in terms of coherent decay of the LO-phonon-plasmon mixed mode in the weak-coupling regime and yield information on the plasmon and electron relaxation. The estimated average electron momentum relaxation times are smaller than those deduced from Hall mobility measurements, as expected from our theoretical model.

Performance Evaluation of LoRa Considering Scenario Conditions.

PubMed

Sanchez-Iborra, Ramon; Sanchez-Gomez, Jesus; Ballesta-Viñas, Juan; Cano, Maria-Dolores; Skarmeta, Antonio F

2018-03-03

New verticals within the Internet of Things (IoT) paradigm such as smart cities, smart farming, or goods monitoring, among many others, are demanding strong requirements to the Radio Access Network (RAN) in terms of coverage, end-node's power consumption, and scalability. The technologies employed so far to provide IoT scenarios with connectivity, e.g., wireless sensor network and cellular technologies, are not able to simultaneously cope with these three requirements. Thus, a novel solution known as Low Power - Wide Area Network (LP-WAN) has emerged as a promising alternative to provide with low-cost and low-power-consumption connectivity to end-nodes spread in a wide area. Concretely, the Long-Range Wide Area Network (LoRaWAN) technology is one of the LP-WAN platforms that is receiving greater attention from both the industry and the academia. For that reason, in this work, a comprehensive performance evaluation of LoRaWAN under different environmental conditions is presented. The results are obtained from three real scenarios, namely, urban, suburban, and rural, considering both dynamic and static conditions, hence a discussion about the most proper LoRaWAN physical-layer configuration for each scenario is provided. Besides, a theoretical coverage study is also conducted by the use of a radio planning tool considering topographic maps and a precise propagation model. From the attained results, it can be concluded that it is necessary to evaluate the propagation conditions of the deployment scenario prior to the system implantation in order to reach a compromise between the robustness of the network and the transmission data-rate.

A Parametric Study on Using Active Debris Removal to Stabilize the Future LEO Debris Environment

NASA Technical Reports Server (NTRS)

Liou, J.C.

2010-01-01

Recent analyses of the instability of the orbital debris population in the low Earth orbit (LEO) region and the collision between Iridium 33 and Cosmos 2251 have reignited the interest in using active debris removal (ADR) to remediate the environment. There are; however, monumental technical, resources, operational, legal, and political challenges in making economically viable ADR a reality. Before a consensus on the need for ADR can be reached, a careful analysis of the effectiveness of ADR must be conducted. The goal is to demonstrate the feasibility of using ADR to preserve the future environment and to guide its implementation to maximize the benefit-cost ratio. This paper describes a comprehensive sensitivity study on using ADR to stabilize the future LEO debris environment. The NASA long-term, orbital debris evolutionary model, LEGEND, is used to quantify the effects of many key parameters. These parameters include (1) the starting epoch of ADR implementation, (2) various target selection criteria, (3) the benefits of collision avoidance maneuvers, (4) the consequence of targeting specific inclination or altitude regimes, (5) the consequence of targeting specific classes of vehicles, and (6) the timescale of removal. Additional analyses on the importance of postmission disposal and how future launches might affect the requirements to stabilize the environment are also included.

The Many Worlds of Leo Szilard: Physicist, Peacemaker, Provocateur

NASA Astrophysics Data System (ADS)

Lanouette, William

2014-03-01

Best known for being the first to conceive and patent the nuclear chain reaction in the 1930s, Leo Szilard should also be remembered for other insights in both physics and biology, and for historical initiatives to control the A-bomb he helped create. In physics, Szilard applied entropy to data in a seminal 1929 paper that laid the basis for ``information theory.'' Szilard co-designed an electromagnetic refrigerator pump with Einstein in the 1920s, in 1939 he co-designed the first nuclear reactor with Enrico Fermi, and he later thought up and named the nuclear ``breeder'' reactor. Biologist Francois Jacob called Szilard an ``intellectual bumblebee'' for the many novel ideas he shared, including one that earned Jacob and others the Nobel Prize. James D. Watson said that for intellectual stimulation he liked being around Szilard because ``Leo got excited about something before it was true.'' A political activist, Szilard proposed and drafted the 1939 letter Einstein sent to President Franklin Roosevelt that warned of German A-bomb work and led to the Manhattan Project - where Szilard was ``Chief Physicist.'' Yet Szilard then worked tirelessly to curb nuclear weapons, organizing a scientists' petition to President Truman and lobbying Congress for civilian control of the atom. Szilard loved dreaming up new institutions. He helped to create the Pugwash Conferences on Science and World Affairs, and founded the Council for a Livable World - the first political action committee for arms control. In biology, Szilard proposed the European Molecular Biology Organization modeled on CERN, and helped create the Salk Institute for Biological Studies, where he was one of the first fellows. Shy, witty, and eccentric, Szilard wrote a political satire in 1960 that predicted when the US-Soviet nuclear arms race would end in the late 1980s. Another satire, ``My Trial as a War Criminal'' about scientists' responsibilities for weapons of mass destruction, is credited with prompting

Lightweight Specifications for Parallel Correctness

DTIC Science & Technology

2012-12-05

Galenson, Benjamin Hindman, Thibaud Hottelier, Pallavi Joshi, Ben- jamin Lipshitz, Leo Meyerovich, Mayur Naik, Chang-Seo Park, and Philip Reames — many...violating executions. We discuss some of these errors in detail in the CHAPTER 5. SPECIFYING AND CHECKING SEMANTIC ATOMICITY 84 Benchmark Approx. LoC

Positive immunolabelling for feline infectious peritonitis in an African lion (Panthera leo) with bilateral panuveitis.

PubMed

Mwase, M; Shimada, K; Mumba, C; Yabe, J; Squarre, D; Madarame, H

2015-01-01

A 15-year-old male African lion (Panthera leo) was presented with blindness due to bilateral panuveitis with retinal detachment. Feline coronavirus (FCoV) antigen was identified immunohistochemically in ocular macrophages, consistent with a diagnosis of feline infectious peritonitis (FIP) infection. This is the first report of FIP in an African lion and the first report of ocular FIP in a non-domestic felid. Copyright © 2014 Elsevier Ltd. All rights reserved.

The LoTrach system: its role in the prevention of ventilator-associated pneumonia.

PubMed

Fletcher, Andrew J W; Ruffell, Alison J; Young, Peter J

2008-01-01

To discuss the development of the LoTrach system in light of current evidence around the prevention of ventilator-associated pneumonia (VAP) and its practical application in the intensive care setting. VAP causes substantial morbidity and mortality in ventilated patients in the Intensive Care Unit (ICU), increases length of stay in ICU and is extremely costly. Strategies are needed to reduce the risk of VAP. We examine the need for an endotracheal tube (ETT) specifically designed for the critically-ill patient, the development of the LoTrach system from conception to production, and the role of the various components of the system in preventing VAP. Early issues in implementing this revolutionary equipment into ICU are explored and three case studies highlight advantages of this system. The LoTrach system has been designed to facilitate the provision of a number of evidence-based interventions that have been shown to reduce VAP. Pulmonary aspiration is ubiquitous with conventional cuffs but prevented by the cuff of the LoTrach system when held at a constant and safe pressure against the tracheal wall with a cuff pressure controller. Other aspects incorporated in the ETT are aimed at clearing the secretions from the subglottic space, preventing tube occlusion and accidental extubation, and avoiding damage to the airway. In this way the LoTrach system employs a multifactorial approach to the prevention of VAP and the cost savings from LoTrach rather than a standard ETT will be considerable because of an average 3 day reduction in ICU length of stay related to this. It thus has the potential to be a very useful tool in the ICU setting in the prevention of VAP.

Differential Higgs production at N 3LO beyond threshold

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dulat, Falko; Mistlberger, Bernhard; Pelloni, Andrea

We present several key steps towards the computation of differential Higgs boson cross sections at N 3LO in perturbative QCD. Specifically, we work in the framework of Higgs-differential cross sections that allows to compute precise predictions for realistic LHC observables. We demonstrate how to perform an expansion of the analytic N 3LO coefficient functions around the production threshold of the Higgs boson. Our framework allows us to compute to arbitrarily high order in the threshold expansion and we explicitly obtain the first two expansion coefficients in analytic form. Furthermore, we assess the phenomenological viability of threshold expansions for differential distributions.more » We find that while a few terms in the threshold expansion are sufficient to approximate the exact rapidity distribution well, transverse momentum distributions require a signficantly higher number of terms in the expansion to be adequately described. We find that to improve state of the art predictions for the rapidity distribution beyond NNLO even more sub-leading terms in the threshold expansion than presented in this article are required. In addition, we report on an interesting obstacle for the computation of N 3LO corrections with LHAPDF parton distribution functions and our solution. We provide files containing the analytic expressions for the partonic cross sections as supplementary material attached to this paper.« less

Differential Higgs production at N 3LO beyond threshold

DOE PAGES

Dulat, Falko; Mistlberger, Bernhard; Pelloni, Andrea

2018-01-29

We present several key steps towards the computation of differential Higgs boson cross sections at N 3LO in perturbative QCD. Specifically, we work in the framework of Higgs-differential cross sections that allows to compute precise predictions for realistic LHC observables. We demonstrate how to perform an expansion of the analytic N 3LO coefficient functions around the production threshold of the Higgs boson. Our framework allows us to compute to arbitrarily high order in the threshold expansion and we explicitly obtain the first two expansion coefficients in analytic form. Furthermore, we assess the phenomenological viability of threshold expansions for differential distributions.more » We find that while a few terms in the threshold expansion are sufficient to approximate the exact rapidity distribution well, transverse momentum distributions require a signficantly higher number of terms in the expansion to be adequately described. We find that to improve state of the art predictions for the rapidity distribution beyond NNLO even more sub-leading terms in the threshold expansion than presented in this article are required. In addition, we report on an interesting obstacle for the computation of N 3LO corrections with LHAPDF parton distribution functions and our solution. We provide files containing the analytic expressions for the partonic cross sections as supplementary material attached to this paper.« less

A Dynamic/Anisotropic Low Earth Orbit (LEO) Ionizing Radiation Model

NASA Technical Reports Server (NTRS)

Badavi, Francis F.; West, Katie J.; Nealy, John E.; Wilson, John W.; Abrahms, Briana L.; Luetke, Nathan J.

2006-01-01

The International Space Station (ISS) provides the proving ground for future long duration human activities in space. Ionizing radiation measurements in ISS form the ideal tool for the experimental validation of ionizing radiation environmental models, nuclear transport code algorithms, and nuclear reaction cross sections. Indeed, prior measurements on the Space Transportation System (STS; Shuttle) have provided vital information impacting both the environmental models and the nuclear transport code development by requiring dynamic models of the Low Earth Orbit (LEO) environment. Previous studies using Computer Aided Design (CAD) models of the evolving ISS configurations with Thermo Luminescent Detector (TLD) area monitors, demonstrated that computational dosimetry requires environmental models with accurate non-isotropic as well as dynamic behavior, detailed information on rack loading, and an accurate 6 degree of freedom (DOF) description of ISS trajectory and orientation.

A Network Access Control Framework for 6LoWPAN Networks

PubMed Central

Oliveira, Luís M. L.; Rodrigues, Joel J. P. C.; de Sousa, Amaro F.; Lloret, Jaime

2013-01-01

Low power over wireless personal area networks (LoWPAN), in particular wireless sensor networks, represent an emerging technology with high potential to be employed in critical situations like security surveillance, battlefields, smart-grids, and in e-health applications. The support of security services in LoWPAN is considered a challenge. First, this type of networks is usually deployed in unattended environments, making them vulnerable to security attacks. Second, the constraints inherent to LoWPAN, such as scarce resources and limited battery capacity, impose a careful planning on how and where the security services should be deployed. Besides protecting the network from some well-known threats, it is important that security mechanisms be able to withstand attacks that have not been identified before. One way of reaching this goal is to control, at the network access level, which nodes can be attached to the network and to enforce their security compliance. This paper presents a network access security framework that can be used to control the nodes that have access to the network, based on administrative approval, and to enforce security compliance to the authorized nodes. PMID:23334610

An Updated Zero Boil-Off Cryogenic Propellant Storage Analysis Applied to Upper Stages or Depots in a LEO Environment

NASA Technical Reports Server (NTRS)

Plachta, David; Kittel, Peter

2003-01-01

Previous efforts have shown the analytical benefits of zero boil-off (ZBO) cryogenic propellant storage in launch vehicle upper stages of Mars transfer vehicles for conceptual Mars Missions. However, recent NASA mission investigations have looked at a different and broad array of missions, including a variety of orbit transfer vehicle (OTV) propulsion concepts, some requiring cryogenic storage. For many of the missions, this vehicle will remain for long periods (greater than one week) in low earth orbit (LEO), a relatively warm thermal environment. Under this environment, and with an array of tank sizes and propellants, the performance of a ZBO cryogenic storage system is predicted and compared with a traditional, passive-only storage concept. The results show mass savings over traditional, passive-only cryogenic storage when mission durations are less than one week in LEO for oxygen, two weeks for methane, and roughly 2 months for LH2. Cryogenic xenon saves mass over passive storage almost immediately.

Successful management of ivermectin-induced blindness in an African lion (Panthera leo) by intravenous administration of a lipid emulsion.

PubMed

Saqib, Muhammad; Abbas, Ghazanfar; Mughal, Mudassar Niaz

2015-11-26

Ivermectin is widely used in veterinary practice for the treatment of ecto- and endo-parasites. In wildlife, an extra-label use this parasiticide is sometimes associated with toxicity. Different treatment regimens have been used in ivermectin toxicosis. The present report describes a successful reversal of ivermectin toxicity by intravenous administration of a commercially available lipid emulsion in a captive African lion (Panthera leo). A 2-year old captive African lion (Panthera leo) weighing ~130 kg was presented with acute neurological impairment and bilateral blindness that had developed 24 h after ivermectin exposure. The animal was treated with a commercially available lipid emulsion along with supportive therapy and experienced complete recovery. To our knowledge, this is the first case report of the use of lipid emulsion in the management of ivermectin induced blindness in an African lion and it appears that intravenous lipid emulsion may be an effective therapy in ivermectin toxicity in lions. Further testing in expanded clinical trials is clearly warranted.

Curcumin suppresses JNK pathway to attenuate BPA-induced insulin resistance in LO2 cells.

PubMed

Geng, Shanshan; Wang, Shijia; Zhu, Weiwei; Xie, Chunfeng; Li, Xiaoting; Wu, Jieshu; Zhu, Jianyun; Jiang, Ye; Yang, Xue; Li, Yuan; Chen, Yue; Wang, Xiaoqian; Meng, Yu; Zhong, Caiyun

2018-01-01

To examine whether curcumin has protective effect on insulin resistance induced by bisphenol A (BPA) in LO2 cells and whether this effect was mediated by inhibiting the inflammatory mitogen-activated protein kinases (MAPKs) and nuclear factor-κB (NF-κB) pathways. LO2 cells were stimulated with BPA in the presence or absence of curcumin for 5 days. Glucose consumption, activation of insulin signaling, MAPKs and NF-κB pathways, levels of inflammatory cytokines and MDA production were analyzed. Curcumin prevented BPA-induced reduction of glucose consumption and suppression of insulin signaling pathway, indicating curcumin alleviated BPA-triggered insulin resistance in LO2 cells. mRNA and proteins levels of TNF-α and IL-6, as well as MDA level in LO2 cells treated with BPA were decreased by curcumin. Furthermore, curcumin downregulated the activation of p38, JNK, and NF-κB pathways upon stimulation with BPA. Inhibition of JNK pathway, but not p38 nor NF-κB pathway, improved glucose consumption and insulin signaling in BPA-treated LO2 cells. Curcumin inhibits BPA-induced insulin resistance by suppressing JNK pathway. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

G‐LoSA: An efficient computational tool for local structure‐centric biological studies and drug design

PubMed Central

2016-01-01

Abstract Molecular recognition by protein mostly occurs in a local region on the protein surface. Thus, an efficient computational method for accurate characterization of protein local structural conservation is necessary to better understand biology and drug design. We present a novel local structure alignment tool, G‐LoSA. G‐LoSA aligns protein local structures in a sequence order independent way and provides a GA‐score, a chemical feature‐based and size‐independent structure similarity score. Our benchmark validation shows the robust performance of G‐LoSA to the local structures of diverse sizes and characteristics, demonstrating its universal applicability to local structure‐centric comparative biology studies. In particular, G‐LoSA is highly effective in detecting conserved local regions on the entire surface of a given protein. In addition, the applications of G‐LoSA to identifying template ligands and predicting ligand and protein binding sites illustrate its strong potential for computer‐aided drug design. We hope that G‐LoSA can be a useful computational method for exploring interesting biological problems through large‐scale comparison of protein local structures and facilitating drug discovery research and development. G‐LoSA is freely available to academic users at http://im.compbio.ku.edu/GLoSA/. PMID:26813336

G-LoSA: An efficient computational tool for local structure-centric biological studies and drug design.

PubMed

Lee, Hui Sun; Im, Wonpil

2016-04-01

Molecular recognition by protein mostly occurs in a local region on the protein surface. Thus, an efficient computational method for accurate characterization of protein local structural conservation is necessary to better understand biology and drug design. We present a novel local structure alignment tool, G-LoSA. G-LoSA aligns protein local structures in a sequence order independent way and provides a GA-score, a chemical feature-based and size-independent structure similarity score. Our benchmark validation shows the robust performance of G-LoSA to the local structures of diverse sizes and characteristics, demonstrating its universal applicability to local structure-centric comparative biology studies. In particular, G-LoSA is highly effective in detecting conserved local regions on the entire surface of a given protein. In addition, the applications of G-LoSA to identifying template ligands and predicting ligand and protein binding sites illustrate its strong potential for computer-aided drug design. We hope that G-LoSA can be a useful computational method for exploring interesting biological problems through large-scale comparison of protein local structures and facilitating drug discovery research and development. G-LoSA is freely available to academic users at http://im.compbio.ku.edu/GLoSA/. © 2016 The Protein Society.

Performance Evaluation of LoRa Considering Scenario Conditions

PubMed Central

Sanchez-Gomez, Jesus; Ballesta-Viñas, Juan

2018-01-01

New verticals within the Internet of Things (IoT) paradigm such as smart cities, smart farming, or goods monitoring, among many others, are demanding strong requirements to the Radio Access Network (RAN) in terms of coverage, end-node’s power consumption, and scalability. The technologies employed so far to provide IoT scenarios with connectivity, e.g., wireless sensor network and cellular technologies, are not able to simultaneously cope with these three requirements. Thus, a novel solution known as Low Power - Wide Area Network (LP-WAN) has emerged as a promising alternative to provide with low-cost and low-power-consumption connectivity to end-nodes spread in a wide area. Concretely, the Long-Range Wide Area Network (LoRaWAN) technology is one of the LP-WAN platforms that is receiving greater attention from both the industry and the academia. For that reason, in this work, a comprehensive performance evaluation of LoRaWAN under different environmental conditions is presented. The results are obtained from three real scenarios, namely, urban, suburban, and rural, considering both dynamic and static conditions, hence a discussion about the most proper LoRaWAN physical-layer configuration for each scenario is provided. Besides, a theoretical coverage study is also conducted by the use of a radio planning tool considering topographic maps and a precise propagation model. From the attained results, it can be concluded that it is necessary to evaluate the propagation conditions of the deployment scenario prior to the system implantation in order to reach a compromise between the robustness of the network and the transmission data-rate. PMID:29510524

Y4lO of Rhizobium sp. Strain NGR234 Is a Symbiotic Determinant Required for Symbiosome Differentiation▿

PubMed Central

Yang, Feng-Juan; Cheng, Li-Li; Zhang, Ling; Dai, Wei-Jun; Liu, Zhe; Yao, Nan; Xie, Zhi-Ping; Staehelin, Christian

2009-01-01

Type 3 (T3) effector proteins, secreted by nitrogen-fixing rhizobia with a bacterial T3 secretion system, affect the nodulation of certain host legumes. The open reading frame y4lO of Rhizobium sp. strain NGR234 encodes a protein with sequence similarities to T3 effectors from pathogenic bacteria (the YopJ effector family). Transcription studies showed that the promoter activity of y4lO depended on the transcriptional activator TtsI. Recombinant Y4lO protein expressed in Escherichia coli did not acetylate two representative mitogen-activated protein kinase kinases (human MKK6 and MKK1 from Medicago truncatula), indicating that YopJ-like proteins differ with respect to their substrate specificities. The y4lO gene was mutated in NGR234 (strain NGRΩy4lO) and in NGRΩnopL, a mutant that does not produce the T3 effector NopL (strain NGRΩnopLΩy4lO). When used as inoculants, the symbiotic properties of the mutants differed. Tephrosia vogelii, Phaseolus vulgaris cv. Yudou No. 1, and Vigna unguiculata cv. Sui Qing Dou Jiao formed pink effective nodules with NGR234 and NGRΩnopLΩy4lO. Nodules induced by NGRΩy4lO were first pink but rapidly turned greenish (ineffective nodules), indicating premature senescence. An ultrastructural analysis of the nodules induced by NGRΩy4lO revealed abnormal formation of enlarged infection droplets in ineffective nodules, whereas symbiosomes harboring a single bacteroid were frequently observed in effective nodules induced by NGR234 or NGRΩnopLΩy4lO. It is concluded that Y4lO is a symbiotic determinant involved in the differentiation of symbiosomes. Y4lO mitigated senescence-inducing effects caused by the T3 effector NopL, suggesting synergistic effects for Y4lO and NopL in nitrogen-fixing nodules. PMID:19060155

Y4lO of Rhizobium sp. strain NGR234 is a symbiotic determinant required for symbiosome differentiation.

PubMed

Yang, Feng-Juan; Cheng, Li-Li; Zhang, Ling; Dai, Wei-Jun; Liu, Zhe; Yao, Nan; Xie, Zhi-Ping; Staehelin, Christian

2009-02-01

Type 3 (T3) effector proteins, secreted by nitrogen-fixing rhizobia with a bacterial T3 secretion system, affect the nodulation of certain host legumes. The open reading frame y4lO of Rhizobium sp. strain NGR234 encodes a protein with sequence similarities to T3 effectors from pathogenic bacteria (the YopJ effector family). Transcription studies showed that the promoter activity of y4lO depended on the transcriptional activator TtsI. Recombinant Y4lO protein expressed in Escherichia coli did not acetylate two representative mitogen-activated protein kinase kinases (human MKK6 and MKK1 from Medicago truncatula), indicating that YopJ-like proteins differ with respect to their substrate specificities. The y4lO gene was mutated in NGR234 (strain NGROmegay4lO) and in NGR Omega nopL, a mutant that does not produce the T3 effector NopL (strain NGR Omega nopLOmegay4lO). When used as inoculants, the symbiotic properties of the mutants differed. Tephrosia vogelii, Phaseolus vulgaris cv. Yudou No. 1, and Vigna unguiculata cv. Sui Qing Dou Jiao formed pink effective nodules with NGR234 and NGR Omega nopL Omega y4lO. Nodules induced by NGR Omega y4lO were first pink but rapidly turned greenish (ineffective nodules), indicating premature senescence. An ultrastructural analysis of the nodules induced by NGR Omega y4lO revealed abnormal formation of enlarged infection droplets in ineffective nodules, whereas symbiosomes harboring a single bacteroid were frequently observed in effective nodules induced by NGR234 or NGR Omega nopL Omega y4lO. It is concluded that Y4lO is a symbiotic determinant involved in the differentiation of symbiosomes. Y4lO mitigated senescence-inducing effects caused by the T3 effector NopL, suggesting synergistic effects for Y4lO and NopL in nitrogen-fixing nodules.

15-LO/15-HETE mediated vascular adventitia fibrosis via p38 MAPK-dependent TGF-β.

PubMed

Zhang, Li; Li, Yumei; Chen, Minggang; Su, Xiaojie; Yi, Dan; Lu, Ping; Zhu, Daling

2014-02-01

15-Lipoxygenase/15-hydroxyeicosatetraenoic acid (15-LO/15-HETE) is known to modulate pulmonary vascular medial hypertrophy and intimal endothelial cells migration and angiogenesis after hypoxia. However, it is unclear whether 15-HETE affects the adventitia of the pulmonary arterial wall. We performed immunohistochemistry, adventitia fibrosis, pulmonary artery fibroblasts phenotype and extracellular matrix (ECM) deposition to determine the role of 15-HETE in hypoxia-induced pulmonary vascular adventitia remodeling. Our studies showed that O2 deprivation induced adventitia hypertrophy of pulmonary arteries with ECM accumulation in both humans with pulmonary arterial hypertension and hypoxic rats. Hypoxia induced 15-LO expression in adventitia. With the inhibitor, NDGA depressed the hypoxia induced ECM deposition and 15-LO production in hypoxic rats. Hypoxia up-regulated the expression of α-SMA, type-Ia collagen and fibronectin in cultured fibroblasts, which seemed to be due to the increased 15-LO/15-HETE. Exogenous 15-HETE mediated the ECM and phenotypic alterations of the fibroblasts as well. The 15-LO/15-HETE induced adventitia fibrosis and fibroblasts phenotypic alterations depended on signaling of the transforming growth factor-β1 (TGF-β1)/Smad2/3 pathway. P38 mitogen-activated protein kinase (p38 MAPKs) was likely to mediate 15-LO induced TGF-β1 and Smad2/3 activation after hypoxia. The results suggest that adventitia fibrosis is an important event in the hypoxia induced pulmonary arterial remodeling, which relies on 15-LO/15-HETE induced p38 MAPK-dependent TGF-β1/Smad2/3 intracellular signaling systems. © 2013 Wiley Periodicals, Inc.

Improving high resolution retinal image quality using speckle illumination HiLo imaging

PubMed Central

Zhou, Xiaolin; Bedggood, Phillip; Metha, Andrew

2014-01-01

Retinal image quality from flood illumination adaptive optics (AO) ophthalmoscopes is adversely affected by out-of-focus light scatter due to the lack of confocality. This effect is more pronounced in small eyes, such as that of rodents, because the requisite high optical power confers a large dioptric thickness to the retina. A recently-developed structured illumination microscopy (SIM) technique called HiLo imaging has been shown to reduce the effect of out-of-focus light scatter in flood illumination microscopes and produce pseudo-confocal images with significantly improved image quality. In this work, we adopted the HiLo technique to a flood AO ophthalmoscope and performed AO imaging in both (physical) model and live rat eyes. The improvement in image quality from HiLo imaging is shown both qualitatively and quantitatively by using spatial spectral analysis. PMID:25136486

Improving high resolution retinal image quality using speckle illumination HiLo imaging.

PubMed

Zhou, Xiaolin; Bedggood, Phillip; Metha, Andrew

2014-08-01

Retinal image quality from flood illumination adaptive optics (AO) ophthalmoscopes is adversely affected by out-of-focus light scatter due to the lack of confocality. This effect is more pronounced in small eyes, such as that of rodents, because the requisite high optical power confers a large dioptric thickness to the retina. A recently-developed structured illumination microscopy (SIM) technique called HiLo imaging has been shown to reduce the effect of out-of-focus light scatter in flood illumination microscopes and produce pseudo-confocal images with significantly improved image quality. In this work, we adopted the HiLo technique to a flood AO ophthalmoscope and performed AO imaging in both (physical) model and live rat eyes. The improvement in image quality from HiLo imaging is shown both qualitatively and quantitatively by using spatial spectral analysis.

Evaluating the environmental criticality of massive objects in LEO for debris mitigation and remediation

NASA Astrophysics Data System (ADS)

Pardini, Carmen; Anselmo, Luciano

2018-04-01

Approximately 95% of the mass in Earth orbit is currently concentrated in about 6700 intact objects, of which nearly 80% are abandoned and more than 90% cannot be maneuvered. The intact objects abandoned in low Earth orbit (LEO) above 650 km, i.e. with an average residual lifetime of more than 25 years, represent the main potential mass reservoir for the generation of new detrimental orbital debris in case of mutual collisions with the existing debris environment, taking into account that an 800 g impactor may be sufficient, in principle, to shatter a 1000 kg spacecraft or rocket stage. Since the 1980's, several mitigation measures were promoted and agreed at the international level in order to prevent the occurrence of new breakups in space and put under control the accumulation of mass abandoned in orbit, but unfortunately the level of compliance with such guidelines, requirements or standards is still far from satisfactory. Moreover, the appearance on the scene of space activity of new private and government actors from a growing number of countries makes the proper management of the circumterrestrial space a task of increasing complexity, taking also into account the rapid emerging of new potential applications, disrupting technologies and operational approaches quite different from the past. In this rapidly evolving environment, it might be useful to have a simple and flexible instrument for evaluating the potential criticality for the environment of massive objects placed or abandoned in LEO. With this goal, in the last few years, a particular effort was devoted to the development of various "criticality indexes", then applied for evaluating many families of rocket bodies and selected spacecraft. In this paper, with the underlining ambition to be simple, intuitive and relevant, from an environmental point of view, a couple of the most complete indexes were coherently applied in order to assess the potential criticality of the most massive objects abandoned in

Leo Spacecraft Charging Design Guidelines: A Proposed NASA Standard

NASA Technical Reports Server (NTRS)

Hillard, G. B.; Ferguson, D. C.

2004-01-01

Over the past decade, Low Earth Orbiting (LEO) spacecraft have gradually required ever-increasing power levels. As a rule, this has been accomplished through the use of high voltage systems. Recent failures and anomalies on such spacecraft have been traced to various design practices and materials choices related to the high voltage solar arrays. NASA Glenn has studied these anomalies including plasma chamber testing on arrays similar to those that experienced difficulties on orbit. Many others in the community have been involved in a comprehensive effort to understand the problems and to develop practices to avoid them. The NASA Space Environments and Effects program, recognizing the timeliness of this effort, commissioned and funded a design guidelines document intended to capture the current state of understanding. This document, which was completed in the spring of 2003, has been submitted as a proposed NASA standard. We present here an overview of this document and discuss the effort to develop it as a NASA standard.

Cranial malformations in related white lions (Panthera leo krugeri).

PubMed

Scaglione, F E; Schröder, C; Degiorgi, G; Zeira, O; Bollo, E

2010-11-01

White lions (Panthera leo krugeri) have never been common in the wild, and at present, the greatest population is kept in zoos where they are bred for biological and biodiversity conservation. During the years 2003 to 2008 in a zoological garden in northern Italy, 19 white lions were born to the same parents, who were in turn paternally consanguineous. Out of the 19 lions, 4 (21%) were stillborn, 13 (69%) died within 1 month, and 1 (5%) was euthanatized after 6 months because of difficulty with prehension of food. Six lions (32%) showed malformations involving the head (jaw, tongue, throat, teeth, and cranial bones). One lion (5%) still alive at 30 months revealed an Arnold-Chiari malformation upon submission for neurological evaluation of postural and gait abnormalities. Paternal consanguinity of the parents, along with inbreeding among white lions in general, could account for the high incidence of congenital malformations of the head in this pride of white lions.

LO2/LH2 propulsion for outer planet orbiter spacecraft

NASA Technical Reports Server (NTRS)

Garrison, P. W.; Sigurdson, K. B.

1983-01-01

Galileo class orbiter missions (750-1500 kg) to the outer planets require a large postinjection delta-V for improved propulsion performance. The present investigation shows that a pump-fed low thrust LO2/LH2 propulsion system can provide a significantly larger net on-orbit mass for a given delta-V than a state-of-the-art earth storable, N2O4/monomethylhydrazine pressure-fed propulsion system. A description is given of a conceptual design for a LO2/LH2 pump-fed propulsion system developed for a Galileo class mission to the outer planets. Attention is given to spacecraft configuration, details regarding the propulsion system, the thermal control of the cryogenic propellants, and aspects of mission performance.

CLINICOPATHOLOGIC FEATURES OF MAMMARY MASSES IN CAPTIVE LIONS (PANTHERA LEO).

PubMed

Sadler, Ryan A; Craig, Linden E; Ramsay, Edward C; Helmick, Kelly; Collins, Darin; Garner, Michael M

2016-03-01

A multi-institutional retrospective analysis of 330 pathology accessions from 285 different lions found 15 captive, female African lions (Panthera leo) with confirmed mammary masses. Aside from the presence of a mammary mass, the most common initial clinical sign was inappetence. Histologic diagnoses were predominantly adenocarcinoma (n = 12), though two benign masses (mammary hyperplasia and a mammary cyst) and one squamous cell carcinoma were identified. Nine of 13 malignant tumors had metastasized to lymph nodes or viscera at the time of necropsy. Six lions with adenocarcinoma and two lions with benign mammary masses had received hormonal contraception, though little evidence of mammary lobular hyperplasia was seen in association with the adenocarcinomas. The most common concurrent disease processes found at necropsy were chronic urinary tract disease and other malignancies. These cases demonstrate that mammary malignancies occur in captive lions and frequently metastasize.

Blood thiamine values in captive adult African lions (Panthera leo).

PubMed

Hoover, John P; DiGesualdo, Cynthia L

2005-09-01

Heparinized whole-blood samples from 22 adult African lions (Panthera leo) fed diets considered nutritionally adequate in 10 American Zoo and Aquarium Association member zoos in North America were provided for this study. Blood thiamine values were estimated using a standard microbiological assay method. The mean +/- standard deviation for blood thiamine values was 249.3 +/- 43.5 nmol/L with a range in values from 160 to 350 nmol/L after exclusion of one outlier. There were no differences (P > 0.05) in the mean blood thiamine values of male and female lions, or of lions that were over and under 10 yr of age. This range (160 to 350 nmol/L) is proposed as a reasonable estimate of the expected range in blood thiamine values for captive adult African lions as currently fed in North American zoos.

Fast Calcium Imaging with Optical Sectioning via HiLo Microscopy.

PubMed

Lauterbach, Marcel A; Ronzitti, Emiliano; Sternberg, Jenna R; Wyart, Claire; Emiliani, Valentina

2015-01-01

Imaging intracellular calcium concentration via reporters that change their fluorescence properties upon binding of calcium, referred to as calcium imaging, has revolutionized our way to probe neuronal activity non-invasively. To reach neurons densely located deep in the tissue, optical sectioning at high rate of acquisition is necessary but difficult to achieve in a cost effective manner. Here we implement an accessible solution relying on HiLo microscopy to provide robust optical sectioning with a high frame rate in vivo. We show that large calcium signals can be recorded from dense neuronal populations at high acquisition rates. We quantify the optical sectioning capabilities and demonstrate the benefits of HiLo microscopy compared to wide-field microscopy for calcium imaging and 3D reconstruction. We apply HiLo microscopy to functional calcium imaging at 100 frames per second deep in biological tissues. This approach enables us to discriminate neuronal activity of motor neurons from different depths in the spinal cord of zebrafish embryos. We observe distinct time courses of calcium signals in somata and axons. We show that our method enables to remove large fluctuations of the background fluorescence. All together our setup can be implemented to provide efficient optical sectioning in vivo at low cost on a wide range of existing microscopes.

Fast Calcium Imaging with Optical Sectioning via HiLo Microscopy

PubMed Central

Sternberg, Jenna R.; Wyart, Claire; Emiliani, Valentina

2015-01-01

Imaging intracellular calcium concentration via reporters that change their fluorescence properties upon binding of calcium, referred to as calcium imaging, has revolutionized our way to probe neuronal activity non-invasively. To reach neurons densely located deep in the tissue, optical sectioning at high rate of acquisition is necessary but difficult to achieve in a cost effective manner. Here we implement an accessible solution relying on HiLo microscopy to provide robust optical sectioning with a high frame rate in vivo. We show that large calcium signals can be recorded from dense neuronal populations at high acquisition rates. We quantify the optical sectioning capabilities and demonstrate the benefits of HiLo microscopy compared to wide-field microscopy for calcium imaging and 3D reconstruction. We apply HiLo microscopy to functional calcium imaging at 100 frames per second deep in biological tissues. This approach enables us to discriminate neuronal activity of motor neurons from different depths in the spinal cord of zebrafish embryos. We observe distinct time courses of calcium signals in somata and axons. We show that our method enables to remove large fluctuations of the background fluorescence. All together our setup can be implemented to provide efficient optical sectioning in vivo at low cost on a wide range of existing microscopes. PMID:26625116

Lo Gnomone Clementino Astronomia Meridiana in Basilica

NASA Astrophysics Data System (ADS)

Sigismondi, Costantino

2014-05-01

Costruito per chiara volontà del papa 70 anni dopo il caso Galileo, lo Gnomone Clementino è un grande telescopio solare che non fa uso di lenti a 92 anni dall’invenzione del cannocchiale. Queste due caratteristiche basterebbero da sole a giustificare l’interesse verso questo strumento. L’astronomia meridiana è alla base dell’astrometria e dell’astrofisica moderna. Lo Gnomone Clementino sta oggi all’astronomia, come il veliero “Amerigo Vespucci” sta alla Marina Italiana. E’ possibile svolgere ogni genere di osservazione e studio su questo strumento, e dal 2002 vi tengo lezioni teorico-pratiche del corso di Storia dell’Astronomia e La Terra nel Sistema Solare della Sapienza, Università di Roma, Facoltà di Lettere e Filosofia. Questo testo aggiunge alcuni tasselli alla ricerca storica sulla meridiana, appoggiandosi, com’è naturale, sulle spalle di giganti che mi hanno preceduto in questi studi. In particolare la misura dell’azimut della meridiana, ed il suo inquadramento tra gli strumenti simili ed alcuni studi di astrometria sui dati del 1701-1703 di Bianchini, che sono apparsi fin’ora soltanto su riviste specializzate ed in Inglese vengono qui proposti in Italiano e semplificati, per valorizzare sempre più questa straordinaria opera d’arte e di scienza.

GNSS VTEC calibration using satellite altimetry and LEO data

NASA Astrophysics Data System (ADS)

Alizadeh, M. Mahdi; Schuh, Harald

2015-04-01

Among different systems remote sensing the ionosphere, space geodetic techniques have turned into a promising tool for monitoring and modeling the ionospheric parameters. Due to the fact that ionosphere is a dispersive medium, the signals travelling through this medium provide information about the parameters of the ionosphere in terms of Total Electron Content (TEC) or electron density along the ray path. The classical input data for development of Global Ionosphere Maps (GIM) of the Vertical Total Electron Content (VTEC) is obtained from the dual-frequency Global Navigation Satellite Systems (GNSS) ground-based observations. Nevertheless due to the fact that GNSS ground stations are in-homogeneously distributed with poor coverage over the oceans (namely southern Pacific and southern Atlantic) and also parts of Africa, the precision of VTEC maps are rather low in these areas. From long term analyses it is believed that the International GNSS Service (IGS) VTEC maps have an accuracy of 1-2 TECU in areas well covered with GNSS receivers; conversely, in areas with poor coverage the accuracy can be degraded by a factor of up to five. On the other hand dual-frequency satellite altimetry missions (such as Jason-1&2) provide direct VTEC values exactly over the oceans, and furthermore the Low Earth Orbiting (LEO) satellites such as the Formosat-3/COSMIC (F/C) provide about a great number of globally distributed occultation measurements per day, which can be used to obtain VTEC values. Combining these data with the ground-based data improves the accuracy and reliability of the VTEC maps by closing of observation gaps that arise when using ground-based data only. In this approach an essential step is the evaluation and calibration of the different data sources used for the combination procedure. This study investigates the compatibility of calibrated TEC observables derived from GNSS dual-frequency data, recorded at global ground-based station networks, with space-based TEC

LPS Increases 5-LO Expression on Monocytes via an Activation of Akt-Sp1/NF-κB Pathways.

PubMed

Lee, Seung Jin; Seo, Kyo Won; Kim, Chi Dae

2015-05-01

5-Lipoxygenase (5-LO) plays a pivotal role in the progression of atherosclerosis. Therefore, this study investigated the molecular mechanisms involved in 5-LO expression on monocytes induced by LPS. Stimulation of THP-1 monocytes with LPS (0~3 µg/ml) increased 5-LO promoter activity and 5-LO protein expression in a concentration-dependent manner. LPS-induced 5-LO expression was blocked by pharmacological inhibition of the Akt pathway, but not by inhibitors of MAPK pathways including the ERK, JNK, and p38 MAPK pathways. In line with these results, LPS increased the phosphorylation of Akt, suggesting a role for the Akt pathway in LPS-induced 5-LO expression. In a promoter activity assay conducted to identify transcription factors, both Sp1 and NF-κB were found to play central roles in 5-LO expression in LPS-treated monocytes. The LPS-enhanced activities of Sp1 and NF-κB were attenuated by an Akt inhibitor. Moreover, the LPS-enhanced phosphorylation of Akt was significantly attenuated in cells pretreated with an anti-TLR4 antibody. Taken together, 5-LO expression in LPS-stimulated monocytes is regulated at the transcriptional level via TLR4/Akt-mediated activations of Sp1 and NF-κB pathways in monocytes.

Sedimentation survey of Lago Loíza, Trujillo Alto, Puerto Rico, July 2009

USGS Publications Warehouse

Soler-López, Luis R.; Licha-Soler, N.A.

2014-01-01

Lago Loíza is a reservoir formed at the confluence of Río Gurabo and Río Grande de Loíza in the municipality of Trujillo Alto in central Puerto Rico, about 10 kilometers (km) north of the town of Caguas, about 9 km northwest of Gurabo, and about 3 km south of Trujillo Alto (fig. 1). The Carraizo Dam is owned and operated by the Puerto Rico Aqueduct and Sewer Authority (PRASA), and was constructed in 1953 as a water-supply reservoir for the San Juan Metropolitan area. The dam is a concrete gravity structure that is located in a shallow valley and has a gently sloping left abutment and steep right abutment. Non-overflow sections flank the spillway section. Waterways include an intake structure for the pumping station and power plant, sluiceways, a trash sluice, and a spillway. The reservoir was built to provide a storage capacity of 26.8 million cubic meters (Mm3) of water at the maximum pool elevation of 41.14 meters (m) above mean sea level (msl) for the Sergio Cuevas Filtration Plant that serves the San Juan metropolitan area. The reservoir has a drainage area of 538 square kilometers (km2) and receives an annual mean rainfall that ranges from 1,600 to 5,000 millimeters per year (mm/yr). The principal streams that drain into Lago Loíza are the Río Grande de Loíza, Río Gurabo, and Río Cañas. Two other rivers, the Río Bairoa and Río Cagüitas, discharge into the Río Grande de Loíza just before it enters the reservoir. The combined mean annual runoff of the Río Grande de Loíza and the Río Gurabo for the 1960–2009 period of record is 323 Mm3. Flow from these streams constitutes about 89 percent of the total mean annual inflow of 364 Mm3 to the reservoir (U.S. Geological Survey, 2009). Detailed information about Lago Loíza reservoir structures, historical sediment accumulation, and a dredge conducted in 1999 are available in Soler-López and Gómez-Gómez (2005). During July 8–15, 2009, the U.S. Geological Survey (USGS) Caribbean Water Science

Analysis Of AVIRIS Data From LEO-15 Using Tafkaa Atmospheric Correction

NASA Technical Reports Server (NTRS)

Montes, Marcos J.; Gao, Bo-Cai; Davis, Curtiss O.; Moline, Mark

2004-01-01

We previously developed an algorithm named Tafkaa for atmospheric correction of remote sensing ocean color data from aircraft and satellite platforms. The algorithm allows quick atmospheric correction of hyperspectral data using lookup tables generated with a modified version of Ahmad & Fraser s vector radiative transfer code. During the past few years we have extended the capabilities of the code. Current modifications include the ability to account for within scene variation in solar geometry (important for very long scenes) and view geometries (important for wide fields of view). Additionally, versions of Tafkaa have been made for a variety of multi-spectral sensors, including SeaWiFS and MODIS. In this proceeding we present some initial results of atmospheric correction of AVIRIS data from the 2001 July Hyperspectral Coastal Ocean Dynamics Experiment (HyCODE) at LEO-15.

A Compilation of Static Stability and Fin Loads Data for Slender Body Missile Models with and without Tail Fins and Wings. Volume 5. Appendix G. Test Number 7, Parts 106 through 175

DTIC Science & Technology

1976-03-01

BiTO ...34 ic2 1~3~ lb*. 蕵"- leo 167 led lo9 170 171 172 17J " 17s 113 17b "薁- O./021 0.7atb ~ "J~7"t7r- J .7736 0.0b21 0.0532...34 C.A14J " "C^Ä37Z"" C.i2id U.ilUT 0.35^3 "J.൫öl- U.27J6 ■ 5.-1519" U.Oddl Ü.-4013 Ü.Ü171 U.0113 U.JJJL Ü.J1S2 U.J434 0.3 leo

Leo Kanner's Mention of 1938 in His Report on Autism Refers to His First Patient.

PubMed

Olmsted, Dan; Blaxill, Mark

2016-01-01

Leo Kanner begins his landmark 1943 case series on autistic children by stating the condition was first brought to his attention in 1938. Recent letters to JADD have described this reference as "mysterious" and speculated it refers to papers published that year by Despert or Asperger. In fact, as Kanner goes on to state, 1938 is when he examined the first child in his case series. An exchange of letters with Despert and later writing by Kanner also point to the originality of his observations.

Leo Schnug: alcoholic dementia as an unexpected source of inspiration for an artist.

PubMed

Sellal, François

2011-01-01

Artistic creativity can be defined as the ability to challenge established academic representations or tastes, and to produce both innovative and esthetic works. Here, we investigate the influence of alcoholic dementia on creativity by describing the case of the famous painter Leo Schnug. It is clear that Schnug's motor and psychic disorders had a dramatic influence on his late artistic output. His hallucinations, panic attacks and delusions had an influence on both the themes and the personal, expressionistic and easily recognizable style of his work. It is unlikely that he would have attained these had he been in good health. Copyright © 2011 S. Karger AG, Basel.

Updating the NASA LEO Orbital Debris Environment Model with Recent Radar and Optical Observations and in Situ Measurements

NASA Technical Reports Server (NTRS)

Liou, J.-C.; Anz-Meador, P.; Matney, M. J.; Kessler, D. J.; Theall, J.; Johnson, N. L.

2000-01-01

The Low Earth Orbit (LEO, between 200 and 2000 km altitudes) debris environment has been constantly measured by NASA Johnson Space Center's Liquid Mirror Telescope (LMT) since 1996 (Africano et al. 1999, NASA JSC-28826) and by Haystack and Haystack Auxiliary radars at MIT Lincoln Laboratory since 1990 (Settecerri et al. 1999, NASA JSC-28744). Debris particles as small as 3 mm can be detected by the radars and as small as 3 cm can be measured by LMT. Objects about 10 cm in diameter and greater are tracked and catalogued by the US Space Surveillance Network. Much smaller (down to several micrometers) natural and debris particle populations can be estimated based on in situ measurements, such as Long Duration Exposure Facility, and based on analyses of returned surfaces, such as Hubble Space Telescope solar arrays, European Retrievable Carrier, and Space Shuttles. To increase our understanding of the current LEO debris environment, the Orbital Debris Program Office at NASA JSC has initiated an effort to improve and update the ORDEM96 model (Kessler et al. 1996, NASA TM-104825) utilizing the recently available data. This paper gives an overview of the new NASA orbital debris engineering model, ORDEM2000.

Forwarding techniques for IP fragmented packets in a real 6LoWPAN network.

PubMed

Ludovici, Alessandro; Calveras, Anna; Casademont, Jordi

2011-01-01

Wireless Sensor Networks (WSNs) are attracting more and more interest since they offer a low-cost solution to the problem of providing a means to deploy large sensor networks in a number of application domains. We believe that a crucial aspect to facilitate WSN diffusion is to make them interoperable with external IP networks. This can be achieved by using the 6LoWPAN protocol stack. 6LoWPAN enables the transmission of IPv6 packets over WSNs based on the IEEE 802.15.4 standard. IPv6 packet size is considerably larger than that of IEEE 802.15.4 data frame. To overcome this problem, 6LoWPAN introduces an adaptation layer between the network and data link layers, allowing IPv6 packets to be adapted to the lower layer constraints. This adaptation layer provides fragmentation and header compression of IP packets. Furthermore, it also can be involved in routing decisions. Depending on which layer is responsible for routing decisions, 6LoWPAN divides routing in two categories: mesh under if the layer concerned is the adaptation layer and route over if it is the network layer. In this paper we analyze different routing solutions (route over, mesh under and enhanced route over) focusing on how they forward fragments. We evaluate their performance in terms of latency and energy consumption when transmitting IP fragmented packets. All the tests have been performed in a real 6LoWPAN implementation. After consideration of the main problems in forwarding of mesh frames in WSN, we propose and analyze a new alternative scheme based on mesh under, which we call controlled mesh under.

Forwarding Techniques for IP Fragmented Packets in a Real 6LoWPAN Network

PubMed Central

Ludovici, Alessandro; Calveras, Anna; Casademont, Jordi

2011-01-01

Wireless Sensor Networks (WSNs) are attracting more and more interest since they offer a low-cost solution to the problem of providing a means to deploy large sensor networks in a number of application domains. We believe that a crucial aspect to facilitate WSN diffusion is to make them interoperable with external IP networks. This can be achieved by using the 6LoWPAN protocol stack. 6LoWPAN enables the transmission of IPv6 packets over WSNs based on the IEEE 802.15.4 standard. IPv6 packet size is considerably larger than that of IEEE 802.15.4 data frame. To overcome this problem, 6LoWPAN introduces an adaptation layer between the network and data link layers, allowing IPv6 packets to be adapted to the lower layer constraints. This adaptation layer provides fragmentation and header compression of IP packets. Furthermore, it also can be involved in routing decisions. Depending on which layer is responsible for routing decisions, 6LoWPAN divides routing in two categories: mesh under if the layer concerned is the adaptation layer and route over if it is the network layer. In this paper we analyze different routing solutions (route over, mesh under and enhanced route over) focusing on how they forward fragments. We evaluate their performance in terms of latency and energy consumption when transmitting IP fragmented packets. All the tests have been performed in a real 6LoWPAN implementation. After consideration of the main problems in forwarding of mesh frames in WSN, we propose and analyze a new alternative scheme based on mesh under, which we call controlled mesh under. PMID:22346615

Four-Wave-Mixing Oscillations in a simplified Boltzmannian semiconductor model with LO-phonons

NASA Astrophysics Data System (ADS)

Tamborenea, P. I.; Bányai, L.; Haug, H.

1996-03-01

The recently discovered(L. Bányai, D. B. Tran Thoai, E. Reitsamer, H. Haug, D. Steinbach, M. U. Wehner, M. Wegener, T. Marschner and W. Stolz, Phys. Rev. Lett. 75), 2188 (1995). oscillations of the integrated four-wave-mixing signal in semiconductors due to electron-LO-phonon scattering are studied within a simplified Boltzmann-type model. Although several aspects of the experimental results require a description within the framework of non-Markovian quantum-kinetic theory, our simplified Boltzmannian model is well suited to analyze the origin of the observed novel oscillations of frequency (1+m_e/m_h) hbarω_LO. To this end, we developed a third-order, analytic solution of the semiconductor Bloch equations (SBE) with Boltzmann-type, LO-phonon collision terms. Results of this theory along with numerical solutions of the SBE will be presented.

12. DETAIL VIEW OF WEST ABUTMENT AT Lo, SHOWING BRIDGE ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

12. DETAIL VIEW OF WEST ABUTMENT AT Lo, SHOWING BRIDGE SEAT, TIMBER PILES, STEEL SILL AND BACKWALL/WlNGWALL BOARDS, LOOKING NORTH - Cottonville Bridge, County Road D-61 at Farmer's Creek, Maquoketa, Jackson County, IA

LEO cooperative multi-spacecraft refueling mission optimization considering J2 perturbation and target's surplus propellant constraint

NASA Astrophysics Data System (ADS)

Zhao, Zhao; Zhang, Jin; Li, Hai-yang; Zhou, Jian-yong

2017-01-01

The optimization of an LEO cooperative multi-spacecraft refueling mission considering the J2 perturbation and target's surplus propellant constraint is studied in the paper. First, a mission scenario is introduced. One service spacecraft and several target spacecraft run on an LEO near-circular orbit, the service spacecraft rendezvouses with some service positions one by one, and target spacecraft transfer to corresponding service positions respectively. Each target spacecraft returns to its original position after obtaining required propellant and the service spacecraft returns to its original position after refueling all target spacecraft. Next, an optimization model of this mission is built. The service sequence, orbital transfer time, and service position are used as deign variables, whereas the propellant cost is used as the design objective. The J2 perturbation, time constraint and the target spacecraft's surplus propellant capability constraint are taken into account. Then, a hybrid two-level optimization approach is presented to solve the formulated mixed integer nonlinear programming (MINLP) problem. A hybrid-encoding genetic algorithm is adopted to seek the near optimal solution in the up-level optimization, while a linear relative dynamic equation considering the J2 perturbation is used to obtain the impulses of orbital transfer in the low-level optimization. Finally, the effectiveness of the proposed model and method is validated by numerical examples.

Research into a Single-aperture Light Field Camera System to Obtain Passive Ground-based 3D Imagery of LEO Objects

NASA Astrophysics Data System (ADS)

Bechis, K.; Pitruzzello, A.

2014-09-01

This presentation describes our ongoing research into using a ground-based light field camera to obtain passive, single-aperture 3D imagery of LEO objects. Light field cameras are an emerging and rapidly evolving technology for passive 3D imaging with a single optical sensor. The cameras use an array of lenslets placed in front of the camera focal plane, which provides angle of arrival information for light rays originating from across the target, allowing range to target and 3D image to be obtained from a single image using monocular optics. The technology, which has been commercially available for less than four years, has the potential to replace dual-sensor systems such as stereo cameras, dual radar-optical systems, and optical-LIDAR fused systems, thus reducing size, weight, cost, and complexity. We have developed a prototype system for passive ranging and 3D imaging using a commercial light field camera and custom light field image processing algorithms. Our light field camera system has been demonstrated for ground-target surveillance and threat detection applications, and this paper presents results of our research thus far into applying this technology to the 3D imaging of LEO objects. The prototype 3D imaging camera system developed by Northrop Grumman uses a Raytrix R5 C2GigE light field camera connected to a Windows computer with an nVidia graphics processing unit (GPU). The system has a frame rate of 30 Hz, and a software control interface allows for automated camera triggering and light field image acquisition to disk. Custom image processing software then performs the following steps: (1) image refocusing, (2) change detection, (3) range finding, and (4) 3D reconstruction. In Step (1), a series of 2D images are generated from each light field image; the 2D images can be refocused at up to 100 different depths. Currently, steps (1) through (3) are automated, while step (4) requires some user interaction. A key requirement for light field camera

Simulation platform of LEO satellite communication system based on OPNET

NASA Astrophysics Data System (ADS)

Zhang, Yu; Zhang, Yong; Li, Xiaozhuo; Wang, Chuqiao; Li, Haihao

2018-02-01

For the purpose of verifying communication protocol in the low earth orbit (LEO) satellite communication system, an Optimized Network Engineering Tool (OPNET) based simulation platform is built. Using the three-layer modeling mechanism, the network model, the node model and the process model of the satellite communication system are built respectively from top to bottom, and the protocol will be implemented by finite state machine and Proto-C language. According to satellite orbit parameters, orbit files are generated via Satellite Tool Kit (STK) and imported into OPNET, and the satellite nodes move along their orbits. The simulation platform adopts time-slot-driven mode, divides simulation time into continuous time slots, and allocates slot number for each time slot. A resource allocation strategy is simulated on this platform, and the simulation results such as resource utilization rate, system throughput and packet delay are analyzed, which indicate that this simulation platform has outstanding versatility.

Blood platelet counts, morphology and morphometry in lions, Panthera leo.

PubMed

Du Plessis, L

2009-09-01

Due to logistical problems in obtaining sufficient blood samples from apparently healthy animals in the wild in order to establish normal haematological reference values, only limited information regarding the blood platelet count and morphology of free-living lions (Panthera leo) is available. This study provides information on platelet counts and describes their morphology with particular reference to size in two normal, healthy and free-ranging lion populations. Blood samples were collected from a total of 16 lions. Platelet counts, determined manually, ranged between 218 and 358 x 10(9)/l. Light microscopy showed mostly activated platelets of various sizes with prominent granules. At the ultrastructural level the platelets revealed typical mammalian platelet morphology. However, morphometric analysis revealed a significant difference (P < 0.001) in platelet size between the two groups of animals. Basic haematological information obtained in this study may be helpful in future comparative studies between animals of the same species as well as in other felids.

A new concept for high-cycle-life LEO: Rechargeable MnO2-hydrogen

NASA Technical Reports Server (NTRS)

Appleby, A. John; Dhar, Y. J.; Murphy, O. J.; Srinivasan, Supramaniam

1989-01-01

The nickel-hydrogen secondary battery system is now the one of choice for use in GEO satellites. It offers superior energy density to that of nickel-cadmium, with a lifetime that is at least comparable in terms of both cycle life and overall operating life. While the number of deep cycles required for GEO use is small, LEO satellites with long lifetimes (5 to 10 years) will require secondary battery systems allowing 30,000 to 60,000 useful cycles which are characterized by an approximately 2C charge rate and C average discharge rate. Recent work has shown that birnessite MnO2 doped with bismuth oxide can be cycled at very high rates (6C) over a very large number of cycles (thousands) at depths-of-discharge in the 85 to 90 percent range, based on two electrons, which discharge at the same potential in a flat plateau. The potential is about 0.7 V vs. hydrogen, with a cut-off at 0.6 V. At first sight, this low voltage would seem to be a disadvantage, since the theoretical energy density will be low. However, it permits the use of lightweight materials that are immune from corrosion at the positive. The high utilization and low equivalent weight of the active material, together with the use of teflon-bonded graphite for current collection, result in very light positives, especially when these are compared with those in a derated nickel-hydrogen system. In addition, the weight of the pressure vessel falls somewhat, since the dead volume is lower. Calculations show that a total system will have 2.5 times the Ah capacity of a derated nickel-hydrogen LEO battery, so that the energy density, based on 1.2 V for nickel-hydrogen and 0.7 V for MnO2-hydrogen, will be 45 percent higher for comparable cycling performance.

Analysis of SEL on Commercial SRAM Memories and Mixed-Field Characterization of a Latchup Detection Circuit for LEO Space Applications

NASA Astrophysics Data System (ADS)

Secondo, R.; Alía, R. Garcia; Peronnard, P.; Brugger, M.; Masi, A.; Danzeca, S.; Merlenghi, A.; Vaillé, J.-R.; Dusseau, L.

2017-08-01

A single event latchup (SEL) experiment based on commercial static random access memory (SRAM) memories has recently been proposed in the framework of the European Organization for Nuclear Research (CERN) Latchup Experiment and Student Satellite nanosatellite low Earth orbit (LEO) space mission. SEL characterization of three commercial SRAM memories has been carried out at the Paul Scherrer Institut (PSI) facility, using monoenergetic focused proton beams and different acquisition setups. The best target candidate was selected and a circuit for SEL detection has been proposed and tested at CERN, in the CERN High Energy AcceleRator Mixed-field facility (CHARM). Experimental results were carried out at test locations representative of the LEO environment, thus providing a full characterization of the SRAM cross sections, together with the analysis of the single-event effect and total ionizing dose of the latchup detection circuit in relation to the particle spectra expected during mission. The setups used for SEL monitoring are described, and details of the proposed circuit components and topology are presented. Experimental results obtained both at PSI and at CHARM facilities are discussed.

BabeLO--An Extensible Converter of Programming Exercises Formats

ERIC Educational Resources Information Center

Queiros, R.; Leal, J. P.

2013-01-01

In the last two decades, there was a proliferation of programming exercise formats that hinders interoperability in automatic assessment. In the lack of a widely accepted standard, a pragmatic solution is to convert content among the existing formats. BabeLO is a programming exercise converter providing services to a network of heterogeneous…

A Study of LoRa: Long Range & Low Power Networks for the Internet of Things.

PubMed

Augustin, Aloÿs; Yi, Jiazi; Clausen, Thomas; Townsley, William Mark

2016-09-09

LoRa is a long-range, low-power, low-bitrate, wireless telecommunications system, promoted as an infrastructure solution for the Internet of Things: end-devices use LoRa across a single wireless hop to communicate to gateway(s), connected to the Internet and which act as transparent bridges and relay messages between these end-devices and a central network server. This paper provides an overview of LoRa and an in-depth analysis of its functional components. The physical and data link layer performance is evaluated by field tests and simulations. Based on the analysis and evaluations, some possible solutions for performance enhancements are proposed.

A Study of LoRa: Long Range & Low Power Networks for the Internet of Things

PubMed Central

Augustin, Aloÿs; Yi, Jiazi; Clausen, Thomas; Townsley, William Mark

2016-01-01

LoRa is a long-range, low-power, low-bitrate, wireless telecommunications system, promoted as an infrastructure solution for the Internet of Things: end-devices use LoRa across a single wireless hop to communicate to gateway(s), connected to the Internet and which act as transparent bridges and relay messages between these end-devices and a central network server. This paper provides an overview of LoRa and an in-depth analysis of its functional components. The physical and data link layer performance is evaluated by field tests and simulations. Based on the analysis and evaluations, some possible solutions for performance enhancements are proposed. PMID:27618064

In vitro characterization of CD133lo cancer stem cells in Retinoblastoma Y79 cell line.

PubMed

Nair, Rohini M; Balla, Murali Ms; Khan, Imran; Kalathur, Ravi Kiran Reddy; Kondaiah, Paturu; Vemuganti, Geeta K

2017-11-21

Retinoblastoma (Rb), the most common childhood intraocular malignant tumor, is reported to have cancer stem cells (CSCs) similar to other tumors. Our previous investigation in primary tumors identified the small sized cells with low CD133 (Prominin-1) and high CD44 (Hyaluronic acid receptor) expression to be putative Rb CSCs using flow cytometry (FSC lo /SSC lo /CD133 lo /CD44 hi ). With this preliminary data, we have now utilized a comprehensive approach of in vitro characterization of Y79 Rb cell line following CSC enrichment using CD133 surface marker and subsequent validation to confirm the functional properties of CSCs. The cultured Rb Y79 cells were evaluated for surface markers by flow cytometry and CD133 sorted cells (CD133 lo /CD133 hi ) were compared for CSC characteristics by size/percentage, cell cycle assay, colony formation assay, differentiation, Matrigel transwell invasion assay, cytotoxicity assay, gene expression using microarray and validation by semi-quantitative PCR. Rb Y79 cell line shared the profile (CD133, CD90, CXCR4 and ABCB1) of primary tumors except for CD44 expression. The CD133 lo cells (16.1 ± 0.2%) were FSC lo /SSC lo , predominantly within the G0/G1 phase, formed larger and higher number of colonies with ability to differentiate to CD133 hi cells, exhibited increased invasive potential in a matrigel transwell assay (p < 0.05) and were resistant to Carboplatin treatment (p < 0.001) as compared to CD133 hi cells. The CD133 lo cells showed higher expression of several embryonic stem cell genes (HOXB2, HOXA9, SALL1, NANOG, OCT4, LEFTY), stem cells/progenitor genes (MSI2, BMI1, PROX1, ABCB1, ABCB5, ABCG2), and metastasis related gene- MACC1, when compared to the CD133 hi cells. This study validates the observation from our earlier primary tumor study that CSC properties in Rb Y79 cell line are endowed within the CD133 lo population, evident by their characteristics- i.e. small sized, dormant in nature, increased colony forming

Higgs boson gluon–fusion production at threshold in N 3LO QCD

DOE PAGES

Anastasiou, Charalampos; Duhr, Claude; Dulat, Falko; ...

2014-09-02

We present the cross-section for the threshold production of the Higgs boson at hadron-colliders at next-to-next-to-next-to-leading order (N 3LO) in perturbative QCD. Furthermore, we present an analytic expression for the partonic cross-section at threshold and the impact of these corrections on the numerical estimates for the hadronic cross-section at the LHC. With this result we achieve a major milestone towards a complete evaluation of the cross-section at N 3LO which will reduce the theoretical uncertainty in the determination of the strengths of the Higgs boson interactions.

Temperature dependence of the LO phonon sidebands in free exciton emission of GaN

NASA Astrophysics Data System (ADS)

Xu, S. J.; Li, G. Q.; Xiong, S.-J.; Che, C. M.

2006-04-01

Temperature-dependent radiative recombination of free excitons involving one or two LO phonons in GaN is investigated in detail. It is found that both phonon sidebands possess asymmetric lineshapes and their energy spacings from the zero-phonon line strongly deviate from the characteristic energy of LO phonons as the temperature increases. Furthermore, the deviation rates of one- and two-phonon sidebands are significantly different. Segall-Mahan [Phys. Rev. 171, 935 (1968)] theory, taking the exciton-photon and exciton-phonon interactions into account, is employed to calculate the sidebands of one or two LO phonons for free excitons in a wide temperature range. Excellent agreement between the theory and experiment is achieved by using only one adjustable parameter, which leads to determination of the effective mass of heavy holes (~0.5m0).

Balmer Absorption Lines in FeLoBALs

NASA Astrophysics Data System (ADS)

Aoki, K.; Iwata, I.; Ohta, K.; Tamura, N.; Ando, M.; Akiyama, M.; Kiuchi, G.; Nakanishi, K.

2007-10-01

We discovered non-stellar Balmer absorption lines in two many-narrow-trough FeLoBALs (mntBALs) by the near-infrared spectroscopy with Subaru/CISCO. Presence of the non-stellar Balmer absorption lines is known to date only in the Seyfert galaxy NGC 4151; thus our discovery is the first cases for quasars. Since all known active galactic nuclei with Balmer absorption lines share similar characteristics, it is suggested that there is a population of BAL quasars which have unique structures at their nuclei or unique evolutionary phase.

Revisión de tecnología y riesgos: refinerías de petróleo - Hoja informativa para las comunidades

EPA Pesticide Factsheets

La Agencia de Protección Ambiental (EPA, por sus siglas en inglés) emitió un reglamento final que mejorará significativamente la calidad del aire en los vecindarios cercanos a las refinerías de petróleo mediante un control más exhaustivo de las emisiones a

An inductorless active mixer using stacked nMOS/pMOS configuration and LO shaping technique

NASA Astrophysics Data System (ADS)

Guo, Benqing; Chen, Jun; Wang, Xuebing; Chen, Hongpeng

2018-04-01

In this paper, a CMOS active down-conversion mixer is presented for wideband applications. Specifically, a LO generation chain is suggested to convert AC LO signal to shaped trapezoid burst, which reduces the sinusoidal LO power level requirement by the mixer. The current-reuse technique by stacked nMOS/pMOS architecture is used to save the power consumption of the circuit. Moreover, this complementary configuration is also employed to compensate second-order nonlinearity of the circuit. Implemented in a 0.18-μm CMOS process, post-simulations show that, driven by only ‑10 dBm sinusoidal LO signal, the proposed inductorless mixer provides a maximal conversion gain of 15.7 dB and a noise figure (NF) of 9.1-12 dB across RF input frequency range 0.5-1.6 GHz. The IIP3 and IP1dB of 3.5 dBm and ‑4.8 dBm are obtained, respectively. The mixer core only consumes 3.6 mW from a 1.8-V supply.

BENIGN IDIOPATHIC ESOPHAGEAL STRICTURE IN A LION ( PANTHERA LEO): DILATION BY AN ACHALASIA BALLOON.

PubMed

Ayala, Ignacio; Laredo, Francisco; Escobar; Alberca, Fernando

2018-03-01

A 1-yr old female lion ( Panthera leo) was referred with a 10-mo history of dysphagia for solid food (meat), episodic regurgitation, and poor weight gain. Esophagoscopy confirmed an esophagitis (midesophagus) and a stricture estimated to be of 13 mm diameter. This was subsequently dilated using a 20-mm-diameter balloon for 2 min followed by a 35-mm achalasia balloon for 3 min. The etiology remains undetermined in spite of a thorough history. The animal progressed satisfactorily, reaching 124 kg after 1 yr and has had no further signs. To the authors' knowledge, neither idiopathic esophageal stricture nor dilation using an achalasia balloon has been reported in Panthera spp.

Age Estimation of African Lions Panthera leo by Ratio of Tooth Areas.

PubMed

White, Paula A; Ikanda, Dennis; Ferrante, Luigi; Chardonnet, Philippe; Mesochina, Pascal; Cameriere, Roberto

2016-01-01

Improved age estimation of African lions Panthera leo is needed to address a number of pressing conservation issues. Here we present a formula for estimating lion age to within six months of known age based on measuring the extent of pulp closure from X-rays, or Ratio Of tooth AReas (ROAR). Derived from measurements taken from lions aged 3-13 years for which exact ages were known, the formula explains 92% of the total variance. The method of calculating the pulp/tooth area ratio, which has been used extensively in forensic science, is novel in the study of lion aging. As a quantifiable measure, ROAR offers improved lion age estimates for population modeling and investigations of age-related mortality, and may assist national and international wildlife authorities in judging compliance with regulatory measures involving age.

Design and Development of Multi-Transceiver Lorafi Board consisting LoRa and ESP8266-Wifi Communication Module

NASA Astrophysics Data System (ADS)

Azmi, Noraini; Sudin, Sukhairi; Munirah Kamarudin, Latifah; Zakaria, Ammar; Visvanathan, Retnam; Chew Cheik, Goh; Mamduh Syed Zakaria, Syed Muhammad; Abdullah Alfarhan, Khudhur; Badlishah Ahmad, R.

2018-03-01

The advancement of Micro-Electro-Mechanical-Systems (MEMS), microcontroller technologies and the idea of Internet of Things (IoT) motivates the development of wireless modules (e.g. WiFi, Bluetooth, Zigbee, and LoRa) that are small and affordable. This paper aims to provide detailed information on the development of the LoRaFi board. The LoRaFi 1.0 is a multi-protocol communication board developed by Centre of Excellence for Advanced Sensor Technology (CEASTech). The board was developed for but not limited to monitor the indoor air quality. The board comprises two different wireless communication modules namely, Long-range technology (LoRa) and WiFi (using ESP8266). The board can be configured to communicate either using LoRa or WiFi or both. The board has been tested and the wireless communication operates successfully. Apart from LoRa, WiFi enables data to be forwarded to the cloud/server where the data can be stored for further data analysis. This helps provide users with real-time information on their smartphones or other applications. In the future, researchers will conduct tests to investigate the communication link quality. Newer version with reduced board size and additional wireless communication module will be developed in the future as to increase board flexibility and widen the range of applications that can use the board.

Numerical Investigation of LO2 and LCH4 Storage Tanks on the Lunar Surface

NASA Technical Reports Server (NTRS)

Moder, Jeff; Barsi, Stephen; Kassemi, Mohammad

2008-01-01

Currently NASA is developing technologies to enable human exploration of the lunar surface for duration of up to 210 days. While trade studies are still underway, a cryogenic ascent stage using liquid oxygen (LO2) and liquid methane (LCH4) is being considered for the Altair lunar lander. For a representative Altair cryogenic ascent stage, we present a detailed storage analysis of the LO2 and LCH4 propellant tanks on the lunar surface for durations of up to 210 days. Both the LO2 and LCH4 propellant tanks are assumed to be pressurized with gaseous helium at launch. A two-phase lumped-vapor computational fluid dynamics model has been developed to account for the presence of a noncondensable gas in the ullage. The CFD model is used to simulate the initial pressure response of the propellant tanks while they are subjected to representative heat leak rates on the lunar surface. Once a near stationary state is achieved within the liquid phase, multizone model is used to extrapolate the solution farther in time. For fixed propellant mass and tank size, the long-term pressure response for different helium mass fractions in both the LO2 and LCH4 tanks is examined.

CC2 oscillator strengths within the local framework for calculating excitation energies (LoFEx).

PubMed

Baudin, Pablo; Kjærgaard, Thomas; Kristensen, Kasper

2017-04-14

In a recent work [P. Baudin and K. Kristensen, J. Chem. Phys. 144, 224106 (2016)], we introduced a local framework for calculating excitation energies (LoFEx), based on second-order approximated coupled cluster (CC2) linear-response theory. LoFEx is a black-box method in which a reduced excitation orbital space (XOS) is optimized to provide coupled cluster (CC) excitation energies at a reduced computational cost. In this article, we present an extension of the LoFEx algorithm to the calculation of CC2 oscillator strengths. Two different strategies are suggested, in which the size of the XOS is determined based on the excitation energy or the oscillator strength of the targeted transitions. The two strategies are applied to a set of medium-sized organic molecules in order to assess both the accuracy and the computational cost of the methods. The results show that CC2 excitation energies and oscillator strengths can be calculated at a reduced computational cost, provided that the targeted transitions are local compared to the size of the molecule. To illustrate the potential of LoFEx for large molecules, both strategies have been successfully applied to the lowest transition of the bivalirudin molecule (4255 basis functions) and compared with time-dependent density functional theory.

An Orientation Dependent Size Illusion Is Underpinned by Processing in the Extrastriate Visual Area, LO1.

PubMed

Mikellidou, Kyriaki; Gouws, André D; Clawson, Hannah; Thompson, Peter; Morland, Antony B; Keefe, Bruce D

2016-01-01

We use the simple, but prominent Helmholtz's squares illusion in which a vertically striped square appears wider than a horizontally striped square of identical physical dimensions to determine whether functional magnetic resonance imaging (fMRI) BOLD responses in V1 underpin illusions of size. We report that these simple stimuli which differ in only one parameter, orientation, to which V1 neurons are highly selective elicited activity in V1 that followed their physical, not perceived size. To further probe the role of V1 in the illusion and investigate plausible extrastriate visual areas responsible for eliciting the Helmholtz squares illusion, we performed a follow-up transcranial magnetic stimulation (TMS) experiment in which we compared perceptual judgments about the aspect ratio of perceptually identical Helmholtz squares when no TMS was applied against selective stimulation of V1, LO1, or LO2. In agreement with fMRI results, we report that TMS of area V1 does not compromise the strength of the illusion. Only stimulation of area LO1, and not LO2, compromised significantly the strength of the illusion, consistent with previous research that LO1 plays a role in the processing of orientation information. These results demonstrate the involvement of a specific extrastriate area in an illusory percept of size.

Single-Shot Optical Sectioning Using Two-Color Probes in HiLo Fluorescence Microscopy

PubMed Central

Muro, Eleonora; Vermeulen, Pierre; Ioannou, Andriani; Skourides, Paris; Dubertret, Benoit; Fragola, Alexandra; Loriette, Vincent

2011-01-01

We describe a wide-field fluorescence microscope setup which combines HiLo microscopy technique with the use of a two-color fluorescent probe. It allows one-shot fluorescence optical sectioning of thick biological moving sample which is illuminated simultaneously with a flat and a structured pattern at two different wavelengths. Both homogenous and structured fluorescence images are spectrally separated at detection and combined similarly with the HiLo microscopy technique. We present optically sectioned full-field images of Xenopus laevis embryos acquired at 25 images/s frame rate. PMID:21641327

Low earth orbiting Nadir Etalon Sounding Spectrometer instrument concept for temperature, moisture and trace species, LeoNESS

NASA Technical Reports Server (NTRS)

Kumer, J. B.; Sterritt, L. W.; Roche, A. E.; Rosenberg, W. J.; Morrow, H. E.; Shenk, W. E.; Susskind, J.

1992-01-01

A concept for a low earth orbiting nadir etalon spectrometer sounder (LeoNESS) is described which can achieve retrieval of temperature, H2O, surface, boundary conditions, cloudiness, and trace species with an accuracy that meets or exceeds the AIRS specifications. Options employing 65-K and 30-K detectors are examined; the former may be implemented via passive radiative cooling. The concept, which is derived from the Cryogenic Limb Array Etalon Spectrometer, has the potential for improving the horizontal and vertical resolution.

Characterisation of a LoVo subline resistant to a benzoyl mustard derivative of distamycin A (FCE 24517).

PubMed Central

Capolongo, L.; Melegaro, G.; Broggini, M.; Mongelli, N.; Grandi, M.

1993-01-01

Human colon adenocarcinoma cells (LoVo) resistant to the new antitumor agent FCE 24517 [benzoyl-mustard derivative of distamycin A] (LoVo/24517) are resistant to the selecting agent and related molecules as well as to vinblastine, with marginal or no resistance to other antitumour drugs. Treatment with verapamil, tamoxifen, nicergoline or cyclosporin A only partially restores the activity of FCE 24517 against LoVo/24517 cells. Such results suggest that resistance mechanisms possible specific for this class of compounds are operating. Images Figure 2 PMID:8105866

LX Leo: A High Mass-Ratio Totally Eclipsing W-type W UMa System

NASA Astrophysics Data System (ADS)

Gürol, B.; Michel, R.; Gonzalez, C.

2017-10-01

We present the results of our investigation of the geometrical and physical parameters of the binary system LX Leo. Based on CCD BVRc light curves, and their analyses with the Wilson-Devinney code, new times of minima and light elements have been determined. According to our solution, the system is a high mass-ratio, totally eclipsing, W-type W UMa system. Combining our photometric solution with the empirical relation for W UMa type systems by Dimitrow & Kjurkchieva (2015), we derived the masses and radii of the components to be M1=0.43 M⊙, M2=0.81 M⊙, R1=0.58 R⊙ and R2=0.77 R⊙. In addition, the evolutionary condition of the system is discussed.

Planetary nebulae as standard candles. IV - A test in the Leo I group

NASA Technical Reports Server (NTRS)

Ciardullo, Robin; Jacoby, George H.; Ford, Holland C.

1989-01-01

In this paper, PN are used to determine accurate distances to three galaxies in the Leo I group - The E0 giant elliptical NGC 3379, its optical companion, the SB0 spiral NGC 3384, and the smaller E6 elliptical NGC 3377. In all three galaxies, the luminosity-specific PN number densities are roughly the same, and the derived stellar death rates are in remarkable agreement with the predictions of stellar evolution theory. It is shown that the shape of the forbidden O III 5007 A PN luminosity function is the same in each galaxy and indistinguishable from that observed in M31 and M81. It is concluded that the PN luminosity function is an excellent standard candle for early-type galaxies.

Effects of anaesthesia on proliferation, invasion and apoptosis of LoVo colon cancer cells in vitro.

PubMed

Xu, Y J; Li, S Y; Cheng, Q; Chen, W K; Wang, S L; Ren, Y; Miao, C H

2016-02-01

Tumour cell proliferation, invasion and apoptosis are crucial steps in tumour metastasis. We evaluated the effect of serum from patients undergoing colon cancer surgery receiving thoracic epidural and propofol anaesthesia on colon cancer cell biology. Patients were randomly assigned to receive propofol anaesthesia with a concomitant thoracic epidural (PEA, n = 20) or sevoflurane anaesthesia with opioid analgesia (SGA, n = 20). Venous blood was obtained before induction of anaesthesia and 24 hours postoperatively. The LoVo colon cancer cells were cultured with patient serum from both groups and the effects on proliferation, invasion and apoptosis were measured. Twenty-four hours after surgery, the absorbance value of LoVo cells at 10% serum concentration from PEA was decreased when compared with SGA (0.302 (0.026) vs 0.391 (0.066), p = 0.005). The inhibitory rate of LoVo cells at 10% serum concentration from PEA was higher than that from SGA (p = 0.004) 24 h after surgery. The number of invasive LoVo cells at 10% serum concentration from PEA was reduced when compared with SGA (44 (4) vs 62 (4), p < 0.001). Exposure of LoVo cells to postoperative serum from patients receiving PEA led to a higher luminescence ratio (apoptosis) than those receiving SGA (0.36 (0.04) vs 0.27 (0.05), p < 0.001). Serum from patients receiving PEA for colon cancer surgery inhibited proliferation and invasion of LoVo cells and induced apoptosis in vitro more than that from patients receiving SGA. Anaesthetic technique might influence the serum milieu in a way that affects cancer cell biology and, thereby, tumour metastastasis. © 2015 The Association of Anaesthetists of Great Britain and Ireland.

Prevalence of hematozoans in lions (Panthera leo) and cheetah (Acinonyx jubatus) in Serengeti National Park and Ngorongoro Crater, Tanzania.

PubMed

Averbeck, G A; Bjork, K E; Packer, C; Herbst, L

1990-07-01

Lions (Panthera leo) and cheetah (Acinonyx jubatus) from the Serengeti National Park and Ngorongoro Crater Conservation Area, Tanzania were examined for the presence of blood protozoans. Twenty-eight percent of the lions were infected with Trypanosoma sp. and the prevalence of trypanosome infection varied significantly between adjacent habitats. All of the animals were infected with Hepatozoon sp. and a Theileria sp.-like piroplasm that was morphologically indistinguishable from Theileria felis.

LoRTE: Detecting transposon-induced genomic variants using low coverage PacBio long read sequences.

PubMed

Disdero, Eric; Filée, Jonathan

2017-01-01

Population genomic analysis of transposable elements has greatly benefited from recent advances of sequencing technologies. However, the short size of the reads and the propensity of transposable elements to nest in highly repeated regions of genomes limits the efficiency of bioinformatic tools when Illumina or 454 technologies are used. Fortunately, long read sequencing technologies generating read length that may span the entire length of full transposons are now available. However, existing TE population genomic softwares were not designed to handle long reads and the development of new dedicated tools is needed. LoRTE is the first tool able to use PacBio long read sequences to identify transposon deletions and insertions between a reference genome and genomes of different strains or populations. Tested against simulated and genuine Drosophila melanogaster PacBio datasets, LoRTE appears to be a reliable and broadly applicable tool to study the dynamic and evolutionary impact of transposable elements using low coverage, long read sequences. LoRTE is an efficient and accurate tool to identify structural genomic variants caused by TE insertion or deletion. LoRTE is available for download at http://www.egce.cnrs-gif.fr/?p=6422.

Volumetric HiLo microscopy employing an electrically tunable lens.

PubMed

Philipp, Katrin; Smolarski, André; Koukourakis, Nektarios; Fischer, Andreas; Stürmer, Moritz; Wallrabe, Ulrike; Czarske, Jürgen W

2016-06-27

Electrically tunable lenses exhibit strong potential for fast motion-free axial scanning in a variety of microscopes. However, they also lead to a degradation of the achievable resolution because of aberrations and misalignment between illumination and detection optics that are induced by the scan itself. Additionally, the typically nonlinear relation between actuation voltage and axial displacement leads to over- or under-sampled frame acquisition in most microscopic techniques because of their static depth-of-field. To overcome these limitations, we present an Adaptive-Lens-High-and-Low-frequency (AL-HiLo) microscope that enables volumetric measurements employing an electrically tunable lens. By using speckle-patterned illumination, we ensure stability against aberrations of the electrically tunable lens. Its depth-of-field can be adjusted a-posteriori and hence enables to create flexible scans, which compensates for irregular axial measurement positions. The adaptive HiLo microscope provides an axial scanning range of 1 mm with an axial resolution of about 4 μm and sub-micron lateral resolution over the full scanning range. Proof of concept measurements at home-built specimens as well as zebrafish embryos with reporter gene-driven fluorescence in the thyroid gland are shown.

An Orientation Dependent Size Illusion Is Underpinned by Processing in the Extrastriate Visual Area, LO1

PubMed Central

Mikellidou, Kyriaki; Gouws, André D.; Clawson, Hannah; Thompson, Peter; Morland, Antony B.

2016-01-01

We use the simple, but prominent Helmholtz’s squares illusion in which a vertically striped square appears wider than a horizontally striped square of identical physical dimensions to determine whether functional magnetic resonance imaging (fMRI) BOLD responses in V1 underpin illusions of size. We report that these simple stimuli which differ in only one parameter, orientation, to which V1 neurons are highly selective elicited activity in V1 that followed their physical, not perceived size. To further probe the role of V1 in the illusion and investigate plausible extrastriate visual areas responsible for eliciting the Helmholtz squares illusion, we performed a follow-up transcranial magnetic stimulation (TMS) experiment in which we compared perceptual judgments about the aspect ratio of perceptually identical Helmholtz squares when no TMS was applied against selective stimulation of V1, LO1, or LO2. In agreement with fMRI results, we report that TMS of area V1 does not compromise the strength of the illusion. Only stimulation of area LO1, and not LO2, compromised significantly the strength of the illusion, consistent with previous research that LO1 plays a role in the processing of orientation information. These results demonstrate the involvement of a specific extrastriate area in an illusory percept of size. PMID:27733896

Age Estimation of African Lions Panthera leo by Ratio of Tooth Areas

PubMed Central

Ikanda, Dennis; Ferrante, Luigi; Chardonnet, Philippe; Mesochina, Pascal; Cameriere, Roberto

2016-01-01

Improved age estimation of African lions Panthera leo is needed to address a number of pressing conservation issues. Here we present a formula for estimating lion age to within six months of known age based on measuring the extent of pulp closure from X-rays, or Ratio Of tooth AReas (ROAR). Derived from measurements taken from lions aged 3–13 years for which exact ages were known, the formula explains 92% of the total variance. The method of calculating the pulp/tooth area ratio, which has been used extensively in forensic science, is novel in the study of lion aging. As a quantifiable measure, ROAR offers improved lion age estimates for population modeling and investigations of age-related mortality, and may assist national and international wildlife authorities in judging compliance with regulatory measures involving age. PMID:27089506

Single-shot optical sectioning using two-color probes in HiLo fluorescence microscopy.

PubMed

Muro, Eleonora; Vermeulen, Pierre; Ioannou, Andriani; Skourides, Paris; Dubertret, Benoit; Fragola, Alexandra; Loriette, Vincent

2011-06-08

We describe a wide-field fluorescence microscope setup which combines HiLo microscopy technique with the use of a two-color fluorescent probe. It allows one-shot fluorescence optical sectioning of thick biological moving sample which is illuminated simultaneously with a flat and a structured pattern at two different wavelengths. Both homogenous and structured fluorescence images are spectrally separated at detection and combined similarly with the HiLo microscopy technique. We present optically sectioned full-field images of Xenopus laevis embryos acquired at 25 images/s frame rate. Copyright © 2011 Biophysical Society. Published by Elsevier Inc. All rights reserved.

Wide-field two-photon microscopy with temporal focusing and HiLo background rejection

NASA Astrophysics Data System (ADS)

Yew, Elijah Y. S.; Choi, Heejin; Kim, Daekeun; So, Peter T. C.

2011-03-01

Scanningless depth-resolved microscopy is achieved through spatial-temporal focusing and has been demonstrated previously. The advantage of this method is that a large area may be imaged without scanning resulting in higher throughput of the imaging system. Because it is a widefield technique, the optical sectioning effect is considerably poorer than with conventional spatial focusing two-photon microscopy. Here we propose wide-field two-photon microscopy based on spatio-temporal focusing and employing background rejection based on the HiLo microscope principle. We demonstrate the effects of applying HiLo microscopy to widefield temporally focused two-photon microscopy.

Cholangiocarcinoma of intrahepatic bile ducts with disseminated metastases in an African lion (Panthera leo).

PubMed

Lepri, Elvio; Sforna, Monica; Brachelente, Chiara; Chiara, Brachelente; Vitellozzi, Giovanni; Giovanni, Vitellozzi

2013-06-01

A cholangiocarcinoma is reported in an 18-yr-old, female African lion (Panthera leo). The primary tumor consisted of multifocal to coalescing, hepatic, white-yellow masses distributed throughout the liver lobes. Metastases were present in regional lymph nodes, peritoneal surface, and lungs. Histologically, the tumor was characterized by a tubular pattern with alcian- and periodic acid-Schiff-positive secretory material in cystic spaces. The neoplastic cells were positive to broad-spectrum cytokeratins. Histochemical and immunohistochemical stains were consistent with bile duct carcinoma. Biliary tumors arising from the gallbladder have been reported in lions. However, to the authors' knowledge, this is the first case of intrahepatic bile duct carcinoma reported in an African lion.

Presumed primary thiamine deficiency in a young African lion (Panthera leo).

PubMed

DiGesualdo, Cynthia L; Hoover, John P; Lorenz, Michael D

2005-09-01

A 1-yr-old intact male African lion (Panthera leo) fed only beef muscle meat was evaluated for episodes of hypermetric ataxia, generalized weakness and tonic-clonic front limb movements. A hemogram, biochemical profile, blood lead, electrocardiogram, survey radiographs, and brain computed tomography were normal. Cerebral spinal fluid analyses suggested mild inflammation. Acetylcholine receptor antibody and serologic tests for all infectious agents tested were negative. Clinical signs resolved completely 9 days after instituting oral thiamine (3 mg/kg/day) and a completely nutritional diet. This lion's pretreatment thiamine blood value (11 nmol/L) was markedly lower than that of a healthy lion (191 nmol/L) and a proposed reference range for adult African lions (160-350 nmol/L). The lion remained clinically normal 2 yr later when his blood thiamine value was 340 nmol/L. African lions can develop clinical primary thiamine deficiency and may respond favorably when thiamine treatment and adequate diet are instituted prior to irreversible neuronal necrosis.

Effect of LEO Exposure on Aromatic Polymers Containing Phenylphosphine Oxide Groups

NASA Technical Reports Server (NTRS)

Watson, K. A.; Ghose, S.; Lillehei, P. T.; Smith, J. G., Jr.; Connell, J. W.

2007-01-01

As part of the Materials on The International Space Station Experiment (MISSE), aromatic polymers containing phenylphosphine oxide groups were exposed to low Earth orbit (LEO) for approximately 4 years. All of the aromatic polymers containing phenylphosphine oxide groups survived the exposure despite the high fluence of atomic oxygen that completely eroded other polymer films such as Kapton and Mylar of comparable or greater thickness. The samples consisted of a colorless polyimide film and a poly(arylene ether benzimidazole) film and thread. The samples were characterized for changes in physical properties, thermal/optical properties (i.e. solar absorptivity and thermal emissivity), surface chemistry (X-ray photoelectron spectroscopy), and surface topography (atomic force microscopy). The data from the polymer samples on MISSE were compared to samples from the same batch of material stored under ambient conditions on Earth. In addition, comparisons were made between the MISSE samples and those subjected to shorter term space flight exposures. The results of these analyses will be presented.

Estradiol agonists inhibit human LoVo colorectal-cancer cell proliferation and migration through p53.

PubMed

Hsu, Hsi-Hsien; Kuo, Wei-Wen; Ju, Da-Tong; Yeh, Yu-Lan; Tu, Chuan-Chou; Tsai, Ying-Lan; Shen, Chia-Yao; Chang, Sheng-Huang; Chung, Li-Chin; Huang, Chih-Yang

2014-11-28

To investigate the effects of 17β-estradiol via estrogen receptors (ER) or direct administration of ER agonists on human colorectal cancer. LoVo cells were established from the Bioresource Collection and Research Center and cultured in phenol red-free DMEM (Sigma, United States). To investigate the effects of E2 and/or ER selective agonists on cellular proliferation, LoVo colorectal cells were treated with E2 or ER-selective agonists for 24 h and 48 h and subjected to the MTT (Sigma) assay to find the concentration. And investigate the effects of E2 and/or ER selective agonists on cell used western immunoblotting to find out the diversification of signaling pathways. In order to observe motility and migration the wound healing assay and a transwell chamber (Neuro Probe) plate were tased. For a quantitative measure, we counted the number of migrating cells to the wound area post-wounding for 24 h. We further examined the cellular migration-regulating factors urokinase-type plasminogen activator (u-PA), tissue-type plasminogen activator (t-PA) and matrix metalloproteinase (MMP)-9 in human LoVo cells so gelatin zymography that we used and gelatinolytic activity was visualized by Coomassie blue staining. And these results are presented as means ± SE, and statistical comparisons were made using Student's t-test. The structure was first compared with E2 and ER agonists. We then treated the LoVo cells with E2 and ER agonists (10(-8) mol/L) for 24 h and 48 h and subsequently measured the cell viability using MTT assay. Our results showed that treatment with 17β-estradiol and/or ER agonists in human LoVo colorectal cancer cells activated p53 and then up-regulated p21 and p27 protein levels, subsequently inhibiting the downstream target gene, cyclin D1, which regulates cell proliferation. Taken together, our findings demonstrate the anti-tumorigenesis effects of 17β-estradiol and/or ER agonists and suggest that these compounds may prove to be a potential alternative

K2 photometry and HERMES spectroscopy of the blue supergiant ρ Leo: rotational wind modulation and low-frequency waves

NASA Astrophysics Data System (ADS)

Aerts, C.; Bowman, D. M.; Símon-Díaz, S.; Buysschaert, B.; Johnston, C.; Moravveji, E.; Beck, P. G.; De Cat, P.; Triana, S.; Aigrain, S.; Castro, N.; Huber, D.; White, T.

2018-05-01

We present an 80-d long uninterrupted high-cadence K2 light curve of the B1Iab supergiant ρ Leo (HD 91316), deduced with the method of halo photometry. This light curve reveals a dominant frequency of frot = 0.0373 d-1 and its harmonics. This dominant frequency corresponds with a rotation period of 26.8 d and is subject to amplitude and phase modulation. The K2 photometry additionally reveals multiperiodic low-frequency variability (<1.5 d-1) and is in full agreement with low-cadence high-resolution spectroscopy assembled during 1800 d. The spectroscopy reveals rotational modulation by a dynamic aspherical wind with an amplitude of about 20 km s-1 in the H α line, as well as photospheric velocity variations of a few km s-1 at frequencies in the range 0.2-0.6 d-1 in the Si III 4567 Å line. Given the large macroturbulence needed to explain the spectral line broadening of the star, we interpret the detected photospheric velocity as due to travelling superinertial low-degree large-scale gravity waves with dominant tangential amplitudes and discuss why ρ Leo is an excellent target to study how the observed photospheric variability propagates into the wind.

Characterization of the cataloged Fengyun-1C fragments and their long-term effect on the LEO environment

NASA Astrophysics Data System (ADS)

Liou, J.-C.; Johnson, N. L.

2009-05-01

The intentional breakup of Fengyun-1C on 11 January 2007 created the most severe orbital debris cloud in history. The altitude where the event occurred was probably the worst location for a major breakup in the low Earth orbit (LEO) region, since it was already highly populated with operational satellites and debris generated from previous breakups. The addition of so many fragments not only poses a realistic threat to operational satellites in the region, but also increases the instability (i.e., collision cascade effect) of the debris population there. Detailed analysis of the large Fengyun-1C fragments indicates that their size and area-to-mass ratio (A/M) distributions are very different from those of other known events. About half of the fragments appear to be composed of light-weight materials and more than 100 of them have A/M values exceeding 1 m 2/kg, consistent with thermal blanket and solar panel pieces. In addition, the orbital elements of the fragments suggest non-trivial velocity gain by the fragment cloud during the impact. These important characteristics were incorporated into numerical simulations to assess the long-term impact of the Fengyun-1C fragments to the LEO debris environment. The collision probabilities between the Fengyun-1C fragments and the rest of the catalog population and the population growth in the low Earth orbit region in the next 100 years are summarized in the paper.

Cycle life testing of lithium-ion batteries for small satellite LEO space missions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mayer, S.T.; Feikert, J.H.; Kaschmitter, J.L.

1993-08-16

In 1990, Sony corporation announced their intention to manufacture a rechargeable lithium ion battery, based on the intercalation of lithium ions into a carbonaceous anode. The cells were first introduced for portable telephone use in June, 1991. (1) A 3.6V average cell voltage (4.1-2.75V range); (2) Excellent cycle life (1200 @ 100% DOD); (3) Good capacity retention (70% after 6 months); (4) Wide temperature range performance ({minus}20 to +60{degrees}C); (5) Excellent Discharge rate (82% capacity at 30 min. discharge rate); (6) Excellent Charge rate (100% Charge in <3 hrs); and (7) High energy density (264 W*hr/1 and 120 Whr/kg formore » ``D`` size cell. These specifications show significant promise for application of these batteries in low earth orbit (LEO) small satellites, particularly when compared to existing NiH{sub 2} and NiCd technology. The very high energy density and specific energy will reduce power system volume and weight. The wide temperature range enables simpler thermal design, particularly for new, small, high power satellites. The materials used in the lithium ion batteries are relatively inexpensive and benign, so that we expect costs to come down substantially in the future. The specified cycle life at 100% DOD is also 50% longer than most NiCds, so low DOD (depth of discharge) performance could be substantial. This study was undertaken to: (a) assess the feasibility for using lithium ion cells on small satellite LEO missions and (b) verify the claims of the manufacturer. This was accomplished by performing a detailed autopsy and various depth of discharge and rate tests on the cells. Of special interest was the cycle life performance of these cell at various depths of discharge DOD`s, to get an initial measure of the reduction in capacity fade with cycle conditions. Low DOD`s are used to extend the life of all batteries used in a space application.« less

XYZ-like spectra from Laplace sum rule at N2LO in the chiral limit

NASA Astrophysics Data System (ADS)

Albuquerque, R.; Narison, S.; Fanomezana, F.; Rabemananjara, A.; Rabetiarivony, D.; Randriamanatrika, G.

2016-12-01

We present new compact integrated expressions of QCD spectral functions of heavy-light molecules and four-quark XY Z-like states at lowest order (LO) of perturbative (PT) QCD and up to d = 8 condensates of the Operator Product Expansion (OPE). Then, by including up to next-to-next leading order (N2LO) PT QCD corrections, which we have estimated by assuming the factorization of the four-quark spectral functions, we improve previous LO results from QCD spectral sum rules (QSSR), on the XY Z-like masses and decay constants which suffer from the ill-defined heavy quark mass. PT N3LO corrections are estimated using a geometric growth of the PT series and are included in the systematic errors. Our optimal results based on stability criteria are summarized in Tables 11-14 and compared, in Sec. 10, with experimental candidates and some LO QSSR results. We conclude that the masses of the XZ observed states are compatible with (almost) pure JPC = 1+±, 0++ molecule or/and four-quark states. The ones of the 1-±, 0-± molecule/four-quark states are about 1.5 GeV above the Yc,b mesons experimental candidates and hadronic thresholds. We also find that the couplings of these exotics to the associated interpolating currents are weaker than that of ordinary D,B mesons (fDD ≈ 10-3f D) and may behave numerically as 1/m¯b3/2 (respectively 1/m¯b) for the 1+, 0+ (respectively 1-, 0-) states which can stimulate further theoretical studies of these decay constants.

High-contrast 3D image acquisition using HiLo microscopy with an electrically tunable lens

NASA Astrophysics Data System (ADS)

Philipp, Katrin; Smolarski, André; Fischer, Andreas; Koukourakis, Nektarios; Stürmer, Moritz; Wallrabe, Ulricke; Czarske, Jürgen

2016-04-01

We present a HiLo microscope with an electrically tunable lens for high-contrast three-dimensional image acquisition. HiLo microscopy combines wide field and speckled illumination images to create optically sectioned images. Additionally, the depth-of-field is not fixed, but can be adjusted between wide field and confocal-like axial resolution. We incorporate an electrically tunable lens in the HiLo microscope for axial scanning, to obtain three-dimensional data without the need of moving neither the sample nor the objective. The used adaptive lens consists of a transparent polydimethylsiloxane (PDMS) membrane into which an annular piezo bending actuator is embedded. A transparent fluid is filled between the membrane and the glass substrate. When actuated, the piezo generates a pressure in the lens which deflects the membrane and thus changes the refractive power. This technique enables a large tuning range of the refractive power between 1/f = (-24 . . . 25) 1/m. As the NA of the adaptive lens is only about 0.05, a fixed high-NA lens is included in the setup to provide high resolution. In this contribution, the scan properties and capabilities of the tunable lens in the HiLo microscope are analyzed. Eventually, exemplary measurements are presented and discussed.

Material interactions with the Low Earth Orbital (LEO) environment: Accurate reaction rate measurements

NASA Technical Reports Server (NTRS)

Visentine, James T.; Leger, Lubert J.

1987-01-01

To resolve uncertainties in estimated LEO atomic oxygen fluence and provide reaction product composition data for comparison to data obtained in ground-based simulation laboratories, a flight experiment has been proposed for the space shuttle which utilizes an ion-neutral mass spectrometer to obtain in-situ ambient density measurements and identify reaction products from modeled polymers exposed to the atomic oxygen environment. An overview of this experiment is presented and the methodology of calibrating the flight mass spectrometer in a neutral beam facility prior to its use on the space shuttle is established. The experiment, designated EOIM-3 (Evaluation of Oxygen Interactions with Materials, third series), will provide a reliable materials interaction data base for future spacecraft design and will furnish insight into the basic chemical mechanisms leading to atomic oxygen interactions with surfaces.

On Applicability of Network Coding Technique for 6LoWPAN-based Sensor Networks.

PubMed

Amanowicz, Marek; Krygier, Jaroslaw

2018-05-26

In this paper, the applicability of the network coding technique in 6LoWPAN-based sensor multihop networks is examined. The 6LoWPAN is one of the standards proposed for the Internet of Things architecture. Thus, we can expect the significant growth of traffic in such networks, which can lead to overload and decrease in the sensor network lifetime. The authors propose the inter-session network coding mechanism that can be implemented in resource-limited sensor motes. The solution reduces the overall traffic in the network, and in consequence, the energy consumption is decreased. Used procedures take into account deep header compressions of the native 6LoWPAN packets and the hop-by-hop changes of the header structure. Applied simplifications reduce signaling traffic that is typically occurring in network coding deployments, keeping the solution usefulness for the wireless sensor networks with limited resources. The authors validate the proposed procedures in terms of end-to-end packet delay, packet loss ratio, traffic in the air, total energy consumption, and network lifetime. The solution has been tested in a real wireless sensor network. The results confirm the efficiency of the proposed technique, mostly in delay-tolerant sensor networks.

LoC-SERS toward clinical application: quantification of antibiotics in human urine samples

NASA Astrophysics Data System (ADS)

Hidi, I. J.; Jahn, M.; Weber, K.; Pletz, M. W.; Bocklitz, T. W.; Cialla-May, D.; Popp, J.

2017-02-01

The determination of the concentration of xenobiotics in biological matrix followed by the change of the prescribing procedure plays a major role in the transition from general to personalized medicine. For this contribution, human urine samples collected from healthy volunteers and from patients having urinary tract infection were used as biological matrix to assess the potential and limitation of LoC-SERS to detected levofloxacin and nitroxoline. The determination of both antibiotics at clinically relevant concentrations, 1.38 mM +/- 0.68 mM for levofloxacin and 10-40 µM for nitroxoline, will be presented. For quantification purposes the standard addition method is combined with LoC-SERS.

Aspects of scintillation modelling in LEO-ground free-space optical communications

NASA Astrophysics Data System (ADS)

Moll, Florian

2017-10-01

Free-space optical communications can be used to transmit data from low Earth orbit satellites to ground with very high data rate. In the last section of the downlink, the electro-magnetic wave propagates through the turbulent atmosphere which is characterized by random index of refraction fluctuations. The propagating wave experiences phase distortions that lead to intensity scintillation in the aperture plane of the receiving telescope. For quantification, an appropriate scintillation model is needed. Approaches to analytically model the scintillation exist. Parameterization of the underlying turbulence profile (Cn2 profile) is however difficult. The Cn2 profiles are often site-specific and thus inappropriate or generic and thus too complex for a feasible deployment. An approach that directly models the scintillation effect based on measurements without claiming to be generic is therefore more feasible. Since measurements are sparse, a combination with existing theoretical framework is feasible to develop a new scintillation model that focuses on low earth orbit to ground free-space optical communications link design with direct detection. The paper addresses several questions one has to answer while analyzing the measurements data and selection of the theoretical models for the LEO downlink scenario. The first is the question of a suitable yet ease to use simple Cn2 profile. The HAP model is analyzed for its feasibility in this scenario since it includes a more realistic boundary layer profile decay than the HV model. It is found that the HAP model needs to be modified for a feasible deployment in the LEO downlink scenario for night time. The validity of the plane wave assumption in the downlink is discussed by model calculations of the scintillation index for a plane and Gaussian beam wave. Inaccuracies when using the plane earth model instead of the spherical earth model are investigated by analyzing the Rytov index. Impact of beam wander and non

Mission Analysis for LEO Microwave Power-Beaming Station in Orbital Launch of Microwave Lightcraft

NASA Technical Reports Server (NTRS)

Myrabo, L. N.; Dickenson, T.

2005-01-01

A detailed mission analysis study has been performed for a 1 km diameter, rechargeable satellite solar power station (SPS) designed to boost 20m diameter, 2400 kg Micr,oWave Lightcraft (MWLC) into low earth orbit (LEO) Positioned in a 476 km daily-repeating oi.bit, the 35 GHz microwave power station is configured like a spinning, thin-film bicycle wheel covered by 30% efficient sola cells on one side and billions of solid state microwave transmitter elements on the other, At the rim of this wheel are two superconducting magnets that can stor,e 2000 G.J of energy from the 320 MW, solar array over a period of several orbits. In preparation for launch, the entire station rotates to coarsely point at the Lightcraft, and then phases up using fine-pointing information sent from a beacon on-board the Lightcraft. Upon demand, the station transmits a 10 gigawatt microwave beam to lift the MWLC from the earth surface into LEO in a flight of several minutes duration. The mission analysis study was comprised of two parts: a) Power station assessment; and b) Analysis of MWLC dynamics during the ascent to orbit including the power-beaming relationships. The power station portion addressed eight critical issues: 1) Drag force vs. station orbital altitude; 2) Solar pressure force on the station; 3) Station orbital lifetime; 4) Feasibility of geo-magnetic re-boost; 5) Beta angle (i..e., sola1 alignment) and power station effective area relationship; 6) Power station percent time in sun vs, mission elapsed time; 7) Station beta angle vs.. charge time; 8) Stresses in station structures.. The launch dynamics portion examined four issues: 1) Ascent mission/trajecto1y profile; 2) MWLC/power-station mission geometry; 3) MWLC thrust angle vs. time; 4) Power station pitch rate during power beaming. Results indicate that approximately 0 58 N of drag force acts upon the station when rotated edge-on to project the minimum frontal area of 5000 sq m. An ion engine or perhaps an electrodynamic

Computer modeling of high-voltage solar array experiment using the NASCAP/LEO (NASA Charging Analyzer Program/Low Earth Orbit) computer code

NASA Astrophysics Data System (ADS)

Reichl, Karl O., Jr.

1987-06-01

The relationship between the Interactions Measurement Payload for Shuttle (IMPS) flight experiment and the low Earth orbit plasma environment is discussed. Two interactions (parasitic current loss and electrostatic discharge on the array) may be detrimental to mission effectiveness. They result from the spacecraft's electrical potentials floating relative to plasma ground to achieve a charge flow equilibrium into the spacecraft. The floating potentials were driven by external biases applied to a solar array module of the Photovoltaic Array Space Power (PASP) experiment aboard the IMPS test pallet. The modeling was performed using the NASA Charging Analyzer Program/Low Earth Orbit (NASCAP/LEO) computer code which calculates the potentials and current collection of high-voltage objects in low Earth orbit. Models are developed by specifying the spacecraft, environment, and orbital parameters. Eight IMPS models were developed by varying the array's bias voltage and altering its orientation relative to its motion. The code modeled a typical low Earth equatorial orbit. NASCAP/LEO calculated a wide variety of possible floating potential and current collection scenarios. These varied directly with both the array bias voltage and with the vehicle's orbital orientation.

Uncontrolled re-entry of satellite parts after finishing their mission in LEO: Titanium alloy degradation by thermite reaction energy

NASA Astrophysics Data System (ADS)

Monogarov, K. A.; Pivkina, A. N.; Grishin, L. I.; Frolov, Yu. V.; Dilhan, D.

2017-06-01

Analytical and experimental studies conducted at Semenov Institute of Chemical Physics for investigating the use of pyrotechnic compositions, i.e., thermites, to reduce the risk of the fall of thermally stable parts of deorbiting end-of-life LEO satellites on the Earth are described. The main idea was the use of passive heating during uncontrolled re-entry to ignite thermite composition, fixed on the titanium surface, with the subsequent combustion energy release to be sufficient to perforate the titanium cover. It is supposed, that thus destructed satellite parts will lose their streamline shape, and will burn out being aerodynamically heated during further descending in atmosphere (patent FR2975080). On the base of thermodynamic calculations the most promising thermite compositions have been selected for the experimental phase. The unique test facilities have been developed for the testing of the efficiency of thermite charges to perforate the titanium TA6V cover of 0.8 mm thickness under temperature/pressure conditions duplicated the uncontrolled re-entry of titanium tank after its mission on LEO. Experiments with the programmed laser heating inside the vacuum chamber revealed the only efficient thermite composition among preliminary selected ones to be Al/Co3O4. Experimental searching of the optimal aluminum powder between spherical and flaked nano- and micron-sized ones revealed the possibility to adjust the necessary ignition delay time, according to the titanium cover temperature dependency on deorbiting time. For the titanium tank the maximum temperature is 1100 °C at altitude 68 km and pressure 60 Pa. Under these conditions Al/Co3O4 formulations with nano-Al spherical particles provide the ignition time to be 13.3 s, and ignition temperature as low as 592±5 °C, whereas compositions with the micron-sized spherical Al powder reveal these values to be much higher, i.e., 26.3 s and 869±5 °C, respectively. The analytical and experimental studies described

Cutaneous squamous cell carcinoma presenting as a wound with discharging sinus tracts in a wild African lion (Panthera leo).

PubMed

Mwase, M; Mumba, C; Square, D; Kawarai, S; Madarame, H

2013-11-01

A female wild African lion (Panthera leo) was presented with an 8-month history of a wound with multiple discharging sinus tracts on the left paw. Microscopical examination revealed squamous cell carcinoma (SCC). To the best of our knowledge, this is the first report of cutaneous SCC in an African lion. Cutaneous SCC presenting as discharging sinus tracts lined by neoplastic squamous cells has not been reported previously in animals. Copyright © 2013 Elsevier Ltd. All rights reserved.

Construction of a Matched Global Cloud and Radiance Product from LEO/GEO and EPIC Observations to Estimate Daytime Earth Radiation Budget from DSCOVR

NASA Astrophysics Data System (ADS)

Duda, D. P.; Khlopenkov, K. V.; Palikonda, R.; Khaiyer, M. M.; Minnis, P.; Su, W.; Sun-Mack, S.

2016-12-01

With the launch of the Deep Space Climate Observatory (DSCOVR), new estimates of the daytime Earth radiation budget can computed from a combination of measurements from the two Earth-observing sensors onboard the spacecraft, the Earth Polychromatic Imaging Camera (EPIC) and the National Institute of Standards and Technology Advanced Radiometer (NISTAR). Although these instruments can provide accurate top-of-atmosphere (TOA) radiance measurements, they lack sufficient resolution to provide details on small-scale surface and cloud properties. Previous studies have shown that these properties have a strong influence on the anisotropy of the radiation at the TOA, and ignoring such effects can result in large TOA-flux errors. To overcome these effects, high-resolution scene identification is needed for accurate Earth radiation budget estimation. Selected radiance and cloud property data measured and derived from several low earth orbit (LEO, including NASA Terra and Aqua MODIS, NOAA AVHRR) and geosynchronous (GEO, including GOES (east and west), METEOSAT, INSAT-3D, MTSAT-2, and HIMAWARI-8) satellite imagers were collected to create hourly 5-km resolution global composites of data necessary to compute angular distribution models (ADM) for reflected shortwave (SW) and longwave (LW) radiation. The satellite data provide an independent source of radiance measurements and scene identification information necessary to construct ADMs that are used to determine the daytime Earth radiation budget. To optimize spatial matching between EPIC measurements and the high-resolution composite cloud properties, LEO/GEO retrievals within the EPIC fields of view (FOV) are convolved to the EPIC point spread function (PSF) in a similar manner to the Clouds and the Earth's Radiant Energy System (CERES) Single Scanner Footprint TOA/Surface Fluxes and Clouds (SSF) product. Examples of the merged LEO/GEO/EPIC product will be presented, describing the chosen radiance and cloud properties and

Construction of a Matched Global Cloud and Radiance Product from LEO/GEO and EPIC Observations to Estimate Daytime Earth Radiation Budget from DSCOVR

NASA Technical Reports Server (NTRS)

Duda, David P.; Khlopenkov, Konstantin V.; Thiemann, Mandana; Palikonda, Rabindra; Sun-Mack, Sunny; Minnis, Patrick; Su, Wenying

2016-01-01

With the launch of the Deep Space Climate Observatory (DSCOVR), new estimates of the daytime Earth radiation budget can be computed from a combination of measurements from the two Earth-observing sensors onboard the spacecraft, the Earth Polychromatic Imaging Camera (EPIC) and the National Institute of Standards and Technology Advanced Radiometer (NISTAR). Although these instruments can provide accurate top-of-atmosphere (TOA) radiance measurements, they lack sufficient resolution to provide details on small-scale surface and cloud properties. Previous studies have shown that these properties have a strong influence on the anisotropy of the radiation at the TOA, and ignoring such effects can result in large TOA-flux errors. To overcome these effects, high-resolution scene identification is needed for accurate Earth radiation budget estimation. Selected radiance and cloud property data measured and derived from several low earth orbit (LEO, including NASA Terra and Aqua MODIS, NOAA AVHRR) and geosynchronous (GEO, including GOES (east and west), METEOSAT, INSAT-3D, MTSAT-2, and HIMAWARI-8) satellite imagers were collected to create hourly 5-km resolution global composites of data necessary to compute angular distribution models (ADM) for reflected shortwave (SW) and longwave (LW) radiation. The satellite data provide an independent source of radiance measurements and scene identification information necessary to construct ADMs that are used to determine the daytime Earth radiation budget. To optimize spatial matching between EPIC measurements and the high-resolution composite cloud properties, LEO/GEO retrievals within the EPIC fields of view (FOV) are convolved to the EPIC point spread function (PSF) in a similar manner to the Clouds and the Earth's Radiant Energy System (CERES) Single Scanner Footprint TOA/Surface Fluxes and Clouds (SSF) product. Examples of the merged LEO/GEO/EPIC product will be presented, describing the chosen radiance and cloud properties and

75 FR 61478 - D'Lo Gas Storage, LLC; Notice of Petition

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-05

... Storage, LLC; Notice of Petition September 24, 2010. Take notice that on September 21, 2010, D'Lo Gas Storage, LLC (Petitioner), 1002 East St. Mary Boulevard, Lafayette, Louisiana 70503, filed in Docket No... determine feasibility of developing the underlying salt dome formation for natural gas storage, all as more...

Systems Analysis of In-Space Manufacturing Applications for the International Space Station and the Evolvable Mars Campaign

NASA Technical Reports Server (NTRS)

Owens, Andrew C.; De Weck, Olivier L.

2016-01-01

Maintenance logistics support is a significant challenge for extended human operations in space, especially for missions beyond Low Earth Orbit (LEO). For missions to Mars (such as NASA's Evolvable Mars Campaign (EMC)), where timely resupply or abort in the event of emergency will not be possible, maintenance logistics mass is directly linked to the Probability of Loss of Crew (P(LoC)), and the cost of driving down risk is an exponential increase in mass requirements. The logistics support strategies that have maintained human operations in LEO will not be effective for these deep space missions. In-Space Manufacturing (ISM) is a promising technological solution that could reduce logistics requirements, mitigate risks, and augment operational capabilities, enabling Earth- independent human spaceflight. This paper reviews maintenance logistics challenges for spaceflight operations in LEO and beyond, and presents a summary of selected results from a systems analysis of potential ISM applications for the ISS and EMC. A quantitative modeling framework and sample assessment of maintenance logistics and risk reduction potential of this new technology is also presented and discussed.

Characterization of the Catalog Fengyun-1C Fragments and Their Long-term Effect on the LEO Environment

NASA Technical Reports Server (NTRS)

Liou, J.-C.; Johnson, N. L.

2008-01-01

The intentional breakup of Fengyun-1C on 11 January 2007 created the most severe orbital debris cloud in history. More than 2500 large fragments were identified and tracked by the U.S. Space Surveillance Network by the end of the year. The altitude where the event occurred was probably the worst location for a major breakup in the low Earth orbit (LEO) region, since it was already highly populated with operational satellites and debris generated from previous breakups. The addition of so many fragments not only poses a realistic threat to operational satellites in the region, but also increases the instability (i.e., collision cascade effect) of the debris population there. Preliminary analysis of the large Fengyun-1C fragments indicates that their size and area-to-mass ratio (A/M) distributions are very different from those of other known events. About half of the fragments appear to be composed of light-weight materials and more than 100 of them have A/M values exceeding 1 square meter per kilogram, consistent with thermal blanket pieces. In addition, the orbital elements of the fragments suggest nontrivial velocity gain by the fragment cloud during the impact. These important characteristics were incorporated into a numerical simulation to assess the long-term impact of the Fengyun-1C fragments to the LEO debris environment. The main objectives of the simulation were to evaluate (1) the collision probabilities between the Fengyun-1C fragments and the rest of the catalog population and (2) the collision activities and population growth in the region in the next 100 years.

Revealing the maternal demographic history of Panthera leo using ancient DNA and a spatially explicit genealogical analysis.

PubMed

Barnett, Ross; Yamaguchi, Nobuyuki; Shapiro, Beth; Ho, Simon Y W; Barnes, Ian; Sabin, Richard; Werdelin, Lars; Cuisin, Jacques; Larson, Greger

2014-04-02

Understanding the demographic history of a population is critical to conservation and to our broader understanding of evolutionary processes. For many tropical large mammals, however, this aim is confounded by the absence of fossil material and by the misleading signal obtained from genetic data of recently fragmented and isolated populations. This is particularly true for the lion which as a consequence of millennia of human persecution, has large gaps in its natural distribution and several recently extinct populations. We sequenced mitochondrial DNA from museum-preserved individuals, including the extinct Barbary lion (Panthera leo leo) and Iranian lion (P. l. persica), as well as lions from West and Central Africa. We added these to a broader sample of lion sequences, resulting in a data set spanning the historical range of lions. Our Bayesian phylogeographical analyses provide evidence for highly supported, reciprocally monophyletic lion clades. Using a molecular clock, we estimated that recent lion lineages began to diverge in the Late Pleistocene. Expanding equatorial rainforest probably separated lions in South and East Africa from other populations. West African lions then expanded into Central Africa during periods of rainforest contraction. Lastly, we found evidence of two separate incursions into Asia from North Africa, first into India and later into the Middle East. We have identified deep, well-supported splits within the mitochondrial phylogeny of African lions, arguing for recognition of some regional populations as worthy of independent conservation. More morphological and nuclear DNA data are now needed to test these subdivisions.

Revealing the maternal demographic history of Panthera leo using ancient DNA and a spatially explicit genealogical analysis

PubMed Central

2014-01-01

Background Understanding the demographic history of a population is critical to conservation and to our broader understanding of evolutionary processes. For many tropical large mammals, however, this aim is confounded by the absence of fossil material and by the misleading signal obtained from genetic data of recently fragmented and isolated populations. This is particularly true for the lion which as a consequence of millennia of human persecution, has large gaps in its natural distribution and several recently extinct populations. Results We sequenced mitochondrial DNA from museum-preserved individuals, including the extinct Barbary lion (Panthera leo leo) and Iranian lion (P. l. persica), as well as lions from West and Central Africa. We added these to a broader sample of lion sequences, resulting in a data set spanning the historical range of lions. Our Bayesian phylogeographical analyses provide evidence for highly supported, reciprocally monophyletic lion clades. Using a molecular clock, we estimated that recent lion lineages began to diverge in the Late Pleistocene. Expanding equatorial rainforest probably separated lions in South and East Africa from other populations. West African lions then expanded into Central Africa during periods of rainforest contraction. Lastly, we found evidence of two separate incursions into Asia from North Africa, first into India and later into the Middle East. Conclusions We have identified deep, well-supported splits within the mitochondrial phylogeny of African lions, arguing for recognition of some regional populations as worthy of independent conservation. More morphological and nuclear DNA data are now needed to test these subdivisions. PMID:24690312

Characterization of the catalog Fengyun-1C fragments and their long-term effect on the LEO environment

NASA Astrophysics Data System (ADS)

Liou, J.-C.

The intentional breakup of Fengyun-1C on 11 January 2007 created the most severe orbital debris cloud in history. More than 2500 large fragments were identified and tracked by the U.S. Space Surveillance Network by the end of the year. The altitude where the event occurred was probably the worst location for a major breakup in the low Earth orbit (LEO) region, since it was already highly populated with operational satellites and debris generated from previous breakups. The addition of so many fragments not only poses a realistic threat to operational satellites in the region, but also increases the instability (i.e., collision cascade effect) of the debris population there. Preliminary analysis of the large Fengyun-1C fragments indicates that their size and area-tomass ratio (A/M) distributions are very different from those of other known events. About half of the fragments appear to be composed of light-weight materials and more than 100 of them have A/M values exceeding 1 m2 /kg, consistent with thermal blanket pieces. In addition, the orbital elements of the fragments suggest non-trivial velocity gain by the fragment cloud during the impact. These important characteristics were incorporated into a numerical simulation to assess the long-term impact of the Fengyun-1C fragments to the LEO debris environment. The main objectives of the simulation were to evaluate (1) the collision probabilities between the Fengyun-1C fragments and the rest of the catalog population and (2) the collision activities and population growth in the region in the next 100 years.

A Channelized 2nd IF/LO Downconverter for the E0S Microwave Limb Sounder

NASA Technical Reports Server (NTRS)

LaBelle, Remi C.

2003-01-01

The Earth Observing System (EOS) Microwave Limb Sounder (MLS) is scheduled for launch in 2004 on the EOS Aura spacecraft. The design, assembly and test of the flight 2nd Intermediate Frequency/ Local Oscillator (2nd IF/LO) subsystem for this instrument has been completed and is presented here. The 2nd IF/LO subsystem consists of 5 separate microwave assemblies, 1 for each of the 5 millimeter wave radiometer front ends, providing a total of 33 separate IF channels. Some key requirements of the subsystem are as follows: provide frequency multiplexing of overlapping or closely spaced 1st IF channels while maintaining low ripple in the passbands; generate 19 different 2nd LO frequencies, in the range of 4-20 GHz, with low phase noise and a placement resolution of 400 KHz; downconvert the 1st IF's to a common 2nd IF frequency centered at 900 MHz; minimize cost and schedule by using common designs for the 5 different assemblies wherever possible.

Malignant lymphoma in african lions (panthera leo).

PubMed

Harrison, T M; McKnight, C A; Sikarskie, J G; Kitchell, B E; Garner, M M; Raymond, J T; Fitzgerald, S D; Valli, V E; Agnew, D; Kiupel, M

2010-09-01

Malignant lymphoma has become an increasingly recognized problem in African lions (Panthera leo). Eleven African lions (9 male and 2 female) with clinical signs and gross and microscopic lesions of malignant lymphoma were evaluated in this study. All animals were older adults, ranging in age from 14 to 19 years. Immunohistochemically, 10 of the 11 lions had T-cell lymphomas (CD3(+), CD79a(-)), and 1 lion was diagnosed with a B-cell lymphoma (CD3(-), CD79a(+)). The spleen appeared to be the primary site of neoplastic growth in all T-cell lymphomas, with involvement of the liver (6/11) and regional lymph nodes (5/11) also commonly observed. The B-cell lymphoma affected the peripheral lymph nodes, liver, and spleen. According to the current veterinary and human World Health Organization classification of hematopoietic neoplasms, T-cell lymphoma subtypes included peripheral T-cell lymphoma (4/11), precursor (acute) T-cell lymphoblastic lymphoma/leukemia (2/11), chronic T-cell lymphocytic lymphoma/leukemia (3/11), and T-zone lymphoma (1/11). The single B-cell lymphoma subtype was consistent with diffuse large B-cell lymphoma. Feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV) testing by immunohistochemistry on sections of malignant lymphoma was negative for all 11 lions. One lion was seropositive for FeLV. In contrast to domestic and exotic cats, in which B-cell lymphomas are more common than T-cell lymphomas, African lions in this study had malignant lymphomas that were primarily of T-cell origin. Neither FeLV nor FIV, important causes of malignant lymphoma in domestic cats, seems to be significant in the pathogenesis of malignant lymphoma in African lions.

A Novel Spacecraft Charge Monitor for LEO

NASA Technical Reports Server (NTRS)

Goembel, Luke

2004-01-01

Five years ago we introduced a new method for measuring spacecraft chassis floating potential relative to the space plasma (absolute spacecraft potential) in low Earth orbit. The method, based on a straightforward interpretation of photoelectron spectra, shows promise for numerous applications, but has not yet been tried. In the interest of testing the method, and ultimately supplying another tool for measuring absolute spacecraft charge, we are producing a flight prototype Spacecraft Charge Monitor (SCM) with support from NASA's Small Business Innovation Research (SBIR) program. Although insight into the technique came from data collected in space over two decades ago, very little data are available. The data indicate that it may be possible to determine spacecraft floating potential to within 0.1 volt each with the SCM second under certain conditions. It is debatable that spacecraft floating potential has ever been measured with such accuracy. The compact, easily deployed SCM also offers the advantage of long-term stability in calibration. Accurate floating potential determinations from the SCM could be used to correct biases in space plasma measurements and evaluate charge mitigation and/or sensing devices. Although this paper focuses on the device's use in low Earth orbit (LEO), the device may also be able to measure spacecraft charge at higher altitudes, in the solar wind, and in orbits around other planets. The flight prototype SCM we are producing for delivery to NASA in the third quarter of 2004 will measure floating potential from 0 to -150 volts with 0.1 volt precision, weigh approximately 600-700 grams, consume approximately 2 watts, and will measure approximately 8 x 10 x 17 cm.

Overexpression of molecular chaperons GRP78 and GRP94 in CD44(hi)/CD24(lo) breast cancer stem cells.

PubMed

Nami, Babak; Ghasemi-Dizgah, Armin; Vaseghi, Akbar

2016-01-01

Breast cancer stem cell with CD44(hi)/CD24(lo) phonotype is described having stem cell properties and represented as the main driving factor in breast cancer initiation, growth, metastasis and low response to anti-cancer agents. Glucoseregulated proteins (GRPs) are heat shock protein family chaperons that are charged with regulation of protein machinery and modulation of endoplasmic reticulum homeostasis whose important roles in stem cell development and invasion of various cancers have been demonstrated. Here, we investigated the expression levels of GRP78 and GRP94 in CD44(hi)/CD24(lo) phenotype breast cancer stem cells (BCSCs). MCF7, T-47D and MDA-MB-231 breast cancer cell lines were used. CD44(hi)/CD24(lo) phenotype cell population were analyzed and sorted by fluorescence-activated cell sorting (FACS). Transcriptional and translational expression of GRP78 and GRP94 were investigated by western blotting and quantitative real time PCR. RESULTS showed different proportion of CD44(hi)/CD24(lo) phenotype cell population in their original bulk cells. The ranking of the cell lines in terms of CD44(hi)/CD24(lo) phenotype cell population was as MCF7lo) phenotype cells exhibited higher mRNA and protein expression level of GRP78 and GRP94 compared to their original bulk cells. Our results show a relationship between overexpression of GRP78 and GRP94 and exhibiting CD44hi/CD24lo phenotype in breast cancer cells. We conclude that upregulation of GRPs may be an important factor in the emergence of CD44hi/CD24lo phenotype BCSCs features.

Hematologic and serum chemistry reference intervals for free-ranging lions (Panthera leo).

PubMed

Maas, Miriam; Keet, Dewald F; Nielen, Mirjam

2013-08-01

Hematologic and serum chemistry values are used by veterinarians and wildlife researchers to assess health status and to identify abnormally high or low levels of a particular blood parameter in a target species. For free-ranging lions (Panthera leo) information about these values is scarce. In this study 7 hematologic and 11 serum biochemistry values were evaluated from 485 lions from the Kruger National Park, South Africa. Significant differences between sexes and sub-adult (≤ 36 months) and adult (>36 months) lions were found for most of the blood parameters and separate reference intervals were made for those values. The obtained reference intervals include the means of the various blood parameter values measured in captive lions, except for alkaline phosphatase in the subadult group. These reference intervals can be utilized for free-ranging lions, and may likely also be used as reference intervals for captive lions. Copyright © 2013 Elsevier Ltd. All rights reserved.

LCTS on ALPHASAT and Sentinel 1a: in orbit status of the LEO to geo data relay system

NASA Astrophysics Data System (ADS)

Zech, H.; Heine, F.; Troendle, D.; Pimentel, P. M.; Panzlaff, K.; Motzigemba, M.; Meyer, R.; Philipp-May, S.

2017-11-01

The performance of sensors for Earth Observation Missions is constantly improving. This drives the need for a reliable, high-speed data transfer capability from a Low Earth Orbit (LEO) spacecraft (S/C) to ground. In addition, for the transfer of time-critical data to ground, a low latency between data generation in orbit and data reception at the respective mission control center is of high importance. Laser communication between Satellites for high data transmission in combination with a GEO data relay system for reducing the latency time addresses these requirements.

Scanning thin-sheet laser imaging microscopy (sTSLIM) with structured illumination and HiLo background rejection.

PubMed Central

Schröter, Tobias J.; Johnson, Shane B.; John, Kerstin; Santi, Peter A.

2011-01-01

We report replacement of one side of a static illumination, dual sided, thin-sheet laser imaging microscope (TSLIM) with an intensity modulated laser scanner in order to implement structured illumination (SI) and HiLo image demodulation techniques for background rejection. The new system is equipped with one static and one scanned light-sheet and is called a scanning thin-sheet laser imaging microscope (sTSLIM). It is an optimized version of a light-sheet fluorescent microscope that is designed to image large specimens (<15 mm in diameter). In this paper we describe the hardware and software modifications to TSLIM that allow for static and uniform light-sheet illumination with SI and HiLo image demodulation. The static light-sheet has a thickness of 3.2 µm; whereas, the scanned side has a light-sheet thickness of 4.2 µm. The scanned side images specimens with subcellular resolution (<1 µm lateral and <4 µm axial resolution) with a size up to 15 mm. SI and HiLo produce superior contrast compared to both the uniform static and scanned light-sheets. HiLo contrast was greater than SI and is faster and more robust than SI because as it produces images in two-thirds of the time and exhibits fewer intensity streaking artifacts. PMID:22254177

The Komplast Experiment: Space Environmental Effects after 12 Years in LEO (and Counting)

NASA Technical Reports Server (NTRS)

Shaevich, S. K.; Aleksandrov, N. G.; Shumov, A. E.; Novikov, L. S.; Alred, J. A.; Shindo, D. J.; Kravchenko, M.; Golden, J. L.

2013-01-01

The Komplast materials experiment was designed by the Khrunichev State Research and Production Space Center, together with other Russian scientific institutes, and has been carried out by Mission Control Moscow since 18. Komplast panels fitted with material samples and sensors were located on the International Space Station (ISS) Functional Cargo Block (FGB) module exterior surface. Within the framework of this experiment, the purpose was to study the effect of the low earth orbit (LEO) environment on exposed samples of various materials. The panels were sent into orbit with the FGB when it launched on November 20, 1998. Panels #2 and #10 were retrieved during Russian extravehicular activity in February 2011 and sealed within cases to temporarily protect the samples from exposure to air until they could be studied on the ground. Panel #2 contained an experiment to detect micrometeoroid and orbital debris (MMOD) impacts, radiation and UV sensors, several pieces of electrical cable, and samples made from elastomeric and fluoroplastic materials. Panel #10 contained a temperature sensor, and both carbon composite and adhesive-bonded samples. A figure shows the location of panels #2 and #10 on the FGB module aft endcone. The panels were subsequently returned to Earth by Space Shuttle Discovery on the STS-133/ULF-5 mission after 12 years of LEO exposure and opened in an argon chamber at the Institute of Nuclear Physics at Moscow State University in July 2011. Based on the results of analyzing the readings from sensors located on Komplast panels and in studying material samples from the panels, the comprehensive effect of spaceflight factors on the FGB (at the locations of Panels #2 and #10) was evaluated. Total solar exposure was determined to be 960 +/- 200 kJ/square cm or 21,000 equivalent solar hours. Because of location of these two panels and the ISS flight attitude, atomic oxygen (AO) fluence was relatively low for such a long duration exposure, approximately 1.5x

Higgs boson production at hadron colliders at N3LO in QCD

NASA Astrophysics Data System (ADS)

Mistlberger, Bernhard

2018-05-01

We present the Higgs boson production cross section at Hadron colliders in the gluon fusion production mode through N3LO in perturbative QCD. Specifically, we work in an effective theory where the top quark is assumed to be infinitely heavy and all other quarks are considered to be massless. Our result is the first exact formula for a partonic hadron collider cross section at N3LO in perturbative QCD. Furthermore, our result is an analytic computation of a hadron collider cross section involving elliptic integrals. We derive numerical predictions for the Higgs boson cross section at the LHC. Previously this result was approximated by an expansion of the cross section around the production threshold of the Higgs boson and we compare our findings. Finally, we study the impact of our new result on the state of the art prediction for the Higgs boson cross section at the LHC.

The Physical Constraints on a New LoBAL QSO at z = 4.82

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yi, Weimin; Bai, Jin-Ming; Green, Richard

Very few low-ionization broad absorption line (LoBAL) QSOs have been found at high redshifts, to date. One high-redshift LoBAL QSO, J0122+1216, was recently discovered by the Lijiang 2.4 m Telescope, with an initial redshift determination of 4.76. Aiming to investigate its physical properties, we carried out follow-up observations in the optical and near-IR spectroscopy. Near-IR spectra from UKIRT and P200 confirm that it is a LoBAL, with a new redshift determination of 4.82 ± 0.01 based on the Mg ii emission-line. The new Mg ii redshift determination reveals strong blueshifts and asymmetry of the high-ionization emission lines. We estimate amore » black hole mass of ∼2.3 × 10{sup 9} M {sub ⊙} and Eddington ratio of ∼1.0 according to the empirical Mg ii-based single-epoch relation and bolometric correction factor. It is possible that strong outflows are the result of an extreme quasar environment driven by the high Eddington ratio. A lower limit on the outflowing kinetic power (>0.9% L {sub Edd}) is derived from both emission and absorption lines, indicating that these outflows play a significant role in the feedback process that regulates the growth of its black hole, as well as host galaxy evolution.« less

LoRa Mobile-To-Base-Station Channel Characterization in the Antarctic.

PubMed

Gaelens, Johnny; Van Torre, Patrick; Verhaevert, Jo; Rogier, Hendrik

2017-08-18

Antarctic conditions demand that wireless sensor nodes are operational all year round and that they provide a large communication range of several tens of kilometers. LoRa technology operating in sub-GHz frequency bands implements these wireless links with minimal power consumption. The employed chirp spread spectrum modulation provides a large link budget, combined with the excellent radio-wave propagation characteristics in these bands. In this paper, an experimental wireless link from a mobile vehicle which transmits sensor data to a base station is measured and analyzed in terms of signal-to-noise ratio and packet loss. These measurements confirm the usefulness of LoRa technology for wireless sensor systems in polar regions. By deploying directional antennas at the base station, a range of up to 30 km is covered in case of Line-of-Sight radio propagation in both the 434 and 868 MHz bands. Varying terrain elevation is shown to be the dominating factor influencing the propagation, sometimes causing the Line-of-Sight path to be obstructed. Tropospheric radio propagation effects were not apparent in the measurements.

LoRa Mobile-To-Base-Station Channel Characterization in the Antarctic

PubMed Central

Gaelens, Johnny; Van Torre, Patrick; Verhaevert, Jo

2017-01-01

Antarctic conditions demand that wireless sensor nodes are operational all year round and that they provide a large communication range of several tens of kilometers. LoRa technology operating in sub-GHz frequency bands implements these wireless links with minimal power consumption. The employed chirp spread spectrum modulation provides a large link budget, combined with the excellent radio-wave propagation characteristics in these bands. In this paper, an experimental wireless link from a mobile vehicle which transmits sensor data to a base station is measured and analyzed in terms of signal-to-noise ratio and packet loss. These measurements confirm the usefulness of LoRa technology for wireless sensor systems in polar regions. By deploying directional antennas at the base station, a range of up to 30 km is covered in case of Line-of-Sight radio propagation in both the 434 and 868 MHz bands. Varying terrain elevation is shown to be the dominating factor influencing the propagation, sometimes causing the Line-of-Sight path to be obstructed. Tropospheric radio propagation effects were not apparent in the measurements. PMID:28820477

Productive High Performance Parallel Programming with Auto-tuned Domain-Specific Embedded Languages

DTIC Science & Technology

2013-01-02

Compilation JVM Java Virtual Machine KB Kilobyte KDT Knowledge Discovery Toolbox LAPACK Linear Algebra Package LLVM Low-Level Virtual Machine LOC Lines...different starting points. Leo Meyerovich also helped solidify some of the ideas here in discussions during Par Lab retreats. I would also like to thank...multi-timestep computations by blocking in both time and space. 88 Implementation Output Approx DSL Type Language Language Parallelism LoC Graphite

Three Canted Radiator Panels to Provide Adequate Cooling for Instruments on Slewing Spacecraft in LEO

NASA Technical Reports Server (NTRS)

Choi, Michael K.

2012-01-01

Certain free-flying spacecraft in low Earth orbit (LEO) or payloads on the International Space Station (ISS) are required to slew to point the telescopes at targets. Instrument detectors and electronics require cooling. Traditionally a planar thermal radiator is used. The temperature of such a radiator varies significantly when the spacecraft slews because its view factors to space vary significantly. Also for payloads on the ISS, solar impingement on the radiator is possible. These thermal adversities could lead to inadequate cooling for the instrument. This paper presents a novel thermal design concept that utilizes three canted radiator panels to mitigate this problem. It increases the overall radiator view factor to cold space and reduces the overall solar or albedo flux absorbed per unit area of the radiator.

A local framework for calculating coupled cluster singles and doubles excitation energies (LoFEx-CCSD)

DOE PAGES

Baudin, Pablo; Bykov, Dmytro; Liakh, Dmitry I.; ...

2017-02-22

Here, the recently developed Local Framework for calculating Excitation energies (LoFEx) is extended to the coupled cluster singles and doubles (CCSD) model. In the new scheme, a standard CCSD excitation energy calculation is carried out within a reduced excitation orbital space (XOS), which is composed of localised molecular orbitals and natural transition orbitals determined from time-dependent Hartree–Fock theory. The presented algorithm uses a series of reduced second-order approximate coupled cluster singles and doubles (CC2) calculations to optimise the XOS in a black-box manner. This ensures that the requested CCSD excitation energies have been determined to a predefined accuracy compared tomore » a conventional CCSD calculation. We present numerical LoFEx-CCSD results for a set of medium-sized organic molecules, which illustrate the black-box nature of the approach and the computational savings obtained for transitions that are local compared to the size of the molecule. In fact, for such local transitions, the LoFEx-CCSD scheme can be applied to molecular systems where a conventional CCSD implementation is intractable.« less

Production of the small heat shock protein Lo18 from Oenococcus oeni in Lactococcus lactis improves its stress tolerance.

PubMed

Weidmann, Stéphanie; Maitre, Magali; Laurent, Julie; Coucheney, Françoise; Rieu, Aurélie; Guzzo, Jean

2017-04-17

Lactococcus lactis is a lactic acid bacterium widely used in cheese and fermented milk production. During fermentation, L. lactis is subjected to acid stress that impairs its growth. The small heat shock protein (sHsp) Lo18 from the acidophilic species Oenococcus oeni was expressed in L. lactis. This sHsp is known to play an important role in protein protection and membrane stabilization in O. oeni. The role of this sHsp could be studied in L. lactis, since no gene encoding for sHsp has been detected in this species. L. lactis subsp. cremoris strain MG1363 was transformed with the pDLhsp18 plasmid, which is derived from pDL278 and contains the hsp18 gene (encoding Lo18) and its own promoter sequence. The production of Lo18 during stress conditions was checked by immunoblotting and the cellular distribution of Lo18 in L. lactis cells after heat shock was determined. Our results clearly indicated a role for Lo18 in cytoplasmic protein protection and membrane stabilization during stress. The production of sHsp in L. lactis improved tolerance to heat and acid conditions in this species. Finally, the improvement of the L. lactis survival in milk medium thanks to Lo18 was highlighted, suggesting an interesting role of this sHsp. These findings suggest that the expression of a sHsp by a L. lactis strain results in greater resistance to stress, and, can consequently enhance the performances of industrial strains. Copyright © 2016 Elsevier B.V. All rights reserved.

Scanning thin-sheet laser imaging microscopy (sTSLIM) with structured illumination and HiLo background rejection.

PubMed

Schröter, Tobias J; Johnson, Shane B; John, Kerstin; Santi, Peter A

2012-01-01

We report replacement of one side of a static illumination, dual sided, thin-sheet laser imaging microscope (TSLIM) with an intensity modulated laser scanner in order to implement structured illumination (SI) and HiLo image demodulation techniques for background rejection. The new system is equipped with one static and one scanned light-sheet and is called a scanning thin-sheet laser imaging microscope (sTSLIM). It is an optimized version of a light-sheet fluorescent microscope that is designed to image large specimens (<15 mm in diameter). In this paper we describe the hardware and software modifications to TSLIM that allow for static and uniform light-sheet illumination with SI and HiLo image demodulation. The static light-sheet has a thickness of 3.2 µm; whereas, the scanned side has a light-sheet thickness of 4.2 µm. The scanned side images specimens with subcellular resolution (<1 µm lateral and <4 µm axial resolution) with a size up to 15 mm. SI and HiLo produce superior contrast compared to both the uniform static and scanned light-sheets. HiLo contrast was greater than SI and is faster and more robust than SI because as it produces images in two-thirds of the time and exhibits fewer intensity streaking artifacts. 2011 Optical Society of America

Pressure-induced increase of exciton-LO-phonon coupling in a ZnCdSe/ZnSe quantum well

NASA Astrophysics Data System (ADS)

Guo, Z. Z.; Liang, X. X.; Ban, S. L.

2003-07-01

The possibility of pressure-induced increase of exciton-LO-phonon coupling in ZnCdSe/ZnSe quantum wells is studied. The ground state binding energies of the heavy hole excitons are calculated using a variational method with consideration of the electron-phonon interaction and the pressure dependence of the parameters. The results show that for quantum wells with intermediate well width, the exciton binding energy and the LO-phonon energy may coincide in the course of pressure increasing, resulting in the increase of exciton-LO-phonon coupling. It is also found that among the pressure-dependent parameters, the influence of the lattice constant is the most important one. The changes of both the effective masses and the dielectric constants have obvious effects on the exciton binding energy, but their influences are counterbalanced.

The PSA−/lo prostate cancer cell population harbors self-renewing long-term tumor-propagating cells that resist castration

PubMed Central

Qin, Jichao; Liu, Xin; Laffin, Brian; Chen, Xin; Choy, Grace; Jeter, Collene; Calhoun-Davis, Tammy; Li, Hangwen; Palapattu, Ganesh S.; Pang, Shen; Lin, Kevin; Huang, Jiaoti; Ivanov, Ivan; Li, Wei; Suraneni, Mahipal V.; Tang, Dean G.

2012-01-01

SUMMARY Prostate cancer (PCa) is heterogeneous and contains both differentiated and undifferentiated tumor cells, but the relative functional contribution of these two cell populations remains unclear. Here we report distinct molecular, cellular, and tumor-propagating properties of PCa cells that express high (PSA+) and low (PSA−/lo) levels of the differentiation marker PSA. PSA−/lo PCa cells are quiescent and refractory to stresses including androgen deprivation, exhibit high clonogenic potential, and possess long-term tumor-propagating capacity. They preferentially express stem cell genes and can undergo asymmetric cell division generating PSA+ cells. Importantly, PSA−/lo PCa cells can initiate robust tumor development and resist androgen ablation in castrated hosts, and harbor highly tumorigenic castration-resistant PCa cells that can be prospectively enriched using ALDH+CD44+α2β1+ phenotype. In contrast, PSA+ PCa cells possess more limited tumor-propagating capacity, undergo symmetric division and are sensitive to castration. Together, our study suggests PSA−/lo cells may represent a critical source of castration-resistant PCa cells. PMID:22560078

Determining the Rotation Periods of an Inactive LEO Satellite and the First Korean Space Debris on GEO, KOREASAT 1

NASA Astrophysics Data System (ADS)

Choi, Jin; Jo, Jung Hyun; Kim, Myung-Jin; Roh, Dong-Goo; Park, Sun-Youp; Lee, Hee-Jae; Park, Maru; Choi, Young-Jun; Yim, Hong-Suh; Bae, Young-Ho; Park, Young-Sik; Cho, Sungki; Moon, Hong-Kyu; Choi, Eun-Jung; Jang, Hyun-Jung; Park, Jang-Hyun

2016-06-01

Inactive space objects are usually rotating and tumbling as a result of internal or external forces. KOREASAT 1 has been inactive since 2005, and its drift trajectory has been monitored with the optical wide-field patrol network (OWL-Net). However, a quantitative analysis of KOREASAT 1 in regard to the attitude evolution has never been performed. Here, two optical tracking systems were used to acquire raw measurements to analyze the rotation period of two inactive satellites. During the optical campaign in 2013, KOREASAT 1 was observed by a 0.6 m class optical telescope operated by the Korea Astronomy and Space Science Institute (KASI). The rotation period of KOREASAT 1 was analyzed with the light curves from the photometry results. The rotation periods of the low Earth orbit (LEO) satellite ASTRO-H after break-up were detected by OWL-Net on April 7, 2016. We analyzed the magnitude variation of each satellite by differential photometry and made comparisons with the star catalog. The illumination effect caused by the phase angle between the Sun and the target satellite was corrected with the system tool kit (STK) and two line element (TLE) technique. Finally, we determined the rotation period of two inactive satellites on LEO and geostationary Earth orbit (GEO) with light curves from the photometry. The main rotation periods were determined to be 5.2 sec for ASTRO-H and 74 sec for KOREASAT 1.

Future orbital transfer vehicle technology study. Volume 1: Executive summary

NASA Technical Reports Server (NTRS)

Davis, E. E.

1982-01-01

Reusable space and ground based LO2/LH2 OTV's, both advanced space engines and aero assist capability were compared. The SB OTV provided advantages in life cycle cost, performance and potential for improvement. An all LO2/LH2 OTV fleet was also compared with a fleet of LO2/.H2 OTV's and electric OTV's. The normal growth technology electric OTV used silicon cells with heavy shielding and argon ion thrusters. In this case, the LO2/LH2 OTV fleet provided a 23% advantage in total transportation cost. An accelerated technology LF2/LH2 OTV provided improvements in performance relative to LO2/.H2 OTV but has higher DDT&E cost which negated its cost effectiveness. The accelerated technology electric vehicle used GaAs cells and annealing but still did not result in the mixed fleet being any cheaper than an all LO2/LH2 OTV fleet. It is concluded that reusable LO2/LH2 OTV's can serve all general purpose cargo roles between LEO and GEO for the forseeable future. The most significant technology for the second generation vehicle would be space debris protection, on orbit propellant storage and transfer and on orbit maintenance capability.

Characteristics of Offshore Hawai';i Island Seismicity and Velocity Structure, including Lo';ihi Submarine Volcano

NASA Astrophysics Data System (ADS)

Merz, D. K.; Caplan-Auerbach, J.; Thurber, C. H.

2013-12-01

The Island of Hawai';i is home to the most active volcanoes in the Hawaiian Islands. The island's isolated nature, combined with the lack of permanent offshore seismometers, creates difficulties in recording small magnitude earthquakes with accuracy. This background offshore seismicity is crucial in understanding the structure of the lithosphere around the island chain, the stresses on the lithosphere generated by the weight of the islands, and how the volcanoes interact with each other offshore. This study uses the data collected from a 9-month deployment of a temporary ocean bottom seismometer (OBS) network fully surrounding Lo';ihi volcano. This allowed us to widen the aperture of earthquake detection around the Big Island, lower the magnitude detection threshold, and better constrain the hypocentral depths of offshore seismicity that occurs between the OBS network and the Hawaii Volcano Observatory's land based network. Although this study occurred during a time of volcanic quiescence for Lo';ihi, it establishes a basis for background seismicity of the volcano. More than 480 earthquakes were located using the OBS network, incorporating data from the HVO network where possible. Here we present relocated hypocenters using the double-difference earthquake location algorithm HypoDD (Waldhauser & Ellsworth, 2000), as well as tomographic images for a 30 km square area around the summit of Lo';ihi. Illuminated by using the double-difference earthquake location algorithm HypoDD (Waldhauser & Ellsworth, 2000), offshore seismicity during this study is punctuated by events locating in the mantle fault zone 30-50km deep. These events reflect rupture on preexisting faults in the lower lithosphere caused by stresses induced by volcano loading and flexure of the Pacific Plate (Wolfe et al., 2004; Pritchard et al., 2007). Tomography was performed using the double-difference seismic tomography method TomoDD (Zhang & Thurber, 2003) and showed overall velocities to be slower than

Resonant intersubband polariton-LO phonon scattering in an optically pumped polaritonic device

NASA Astrophysics Data System (ADS)

Manceau, J.-M.; Tran, N.-L.; Biasiol, G.; Laurent, T.; Sagnes, I.; Beaudoin, G.; De Liberato, S.; Carusotto, I.; Colombelli, R.

2018-05-01

We report experimental evidence of longitudinal optical (LO) phonon-intersubband polariton scattering processes under resonant injection of light. The scattering process is resonant with both the initial (upper polariton) and final (lower polariton) states and is induced by the interaction of confined electrons with longitudinal optical phonons. The system is optically pumped with a mid-IR laser tuned between 1094 cm-1 and 1134 cm-1 (λ = 9.14 μm and λ = 8.82 μm). The demonstration is provided for both GaAs/AlGaAs and InGaAs/AlInAs doped quantum well systems whose intersubband plasmon lies at a wavelength of ≈10 μm. In addition to elucidating the microscopic mechanism of the polariton-phonon scattering, it is found to differ substantially from the standard single particle electron-LO phonon scattering mechanism, and this work constitutes an important step towards the hopefully forthcoming demonstration of an intersubband polariton laser.

NGSLR's Measurement of the Retro-Reflector Array Response of Various LEO to GNSS Satellites

NASA Technical Reports Server (NTRS)

McGarry, Jan; Clarke, Christopher; Degnan, John; Donovan, Howard; Hall, Benjamin; Hovarth, Julie; Zagwodzki, Thomas

2012-01-01

"NASA's Next Generation Satellite Laser Ranging System (NGSLR) has successfully demonstrated daylight and nighttime tracking this year to s atellites from LEO to GNSS orbits, using a 7-8 arcsecond beam divergence, a 43% QE Hamamatsu MCP-PMT with single photon detection, a narrow field of view (11 arcseconds), and a 1 mJ per pulse 2kHz repetition rate laser. We have compared the actual return rates we are getting against the theoretical link calculations, using the known system confi guration parameters, an estimate of the sky transmission using locall y measured visibility, and signal processing to extract the signal from the background noise. We can achieve good agreement between theory and measurement in most passes by using an estimated pOinting error. We will s.()w the results of this comparison along with our conclusio ns."

Real-time precise orbit determination of LEO satellites using a single-frequency GPS receiver: Preliminary results of Chinese SJ-9A satellite

NASA Astrophysics Data System (ADS)

Sun, Xiucong; Han, Chao; Chen, Pei

2017-10-01

Spaceborne Global Positioning System (GPS) receivers are widely used for orbit determination of low-Earth-orbiting (LEO) satellites. With the improvement of measurement accuracy, single-frequency receivers are recently considered for low-cost small satellite missions. In this paper, a Schmidt-Kalman filter which processes single-frequency GPS measurements and broadcast ephemerides is proposed for real-time precise orbit determination of LEO satellites. The C/A code and L1 phase are linearly combined to eliminate the first-order ionospheric effects. Systematic errors due to ionospheric delay residual, group delay variation, phase center variation, and broadcast ephemeris errors, are lumped together into a noise term, which is modeled as a first-order Gauss-Markov process. In order to reduce computational complexity, the colored noise is considered rather than estimated in the orbit determination process. This ensures that the covariance matrix accurately represents the distribution of estimation errors without increasing the dimension of the state vector. The orbit determination algorithm is tested with actual flight data from the single-frequency GPS receiver onboard China's small satellite Shi Jian-9A (SJ-9A). Preliminary results using a 7-h data arc on October 25, 2012 show that the Schmidt-Kalman filter performs better than the standard Kalman filter in terms of accuracy.

Analysis of Static Spacecraft Floating Potential at Low Earth Orbit (LEO)

NASA Technical Reports Server (NTRS)

Herr, Joel L.; Hwang, K. S.; Wu, S. T.

1995-01-01

Spacecraft floating potential is the charge on the external surfaces of orbiting spacecraft relative to the space. Charging is caused by unequal negative and positive currents to spacecraft surfaces. The charging process continues until the accelerated particles can be collected rapidly enough to balance the currents at which point the spacecraft has reached its equilibrium or floating potential. In low inclination. Low Earth Orbit (LEO), the collection of positive ion and negative electrons. in a particular direction. are typically not equal. The level of charging required for equilibrium to be established is influenced by the characteristics of the ambient plasma environment. by the spacecraft motion, and by the geometry of the spacecraft. Using the kinetic theory, a statistical approach for studying the interaction is developed. The approach used to study the spacecraft floating potential depends on which phenomena are being applied. and on the properties of the plasma. especially the density and temperature. The results from kinetic theory derivation are applied to determine the charging level and the electric potential distribution at an infinite flat plate perpendicular to a streaming plasma using finite-difference scheme.

Location and removal of deslorelin acetate implants in female African lions (Panthera leo).

PubMed

Moresco, Anneke; Dadone, Liza; Arble, Jason; Klaphake, Eric; Agnew, Dalen W

2014-06-01

Contraception is necessary to manage zoo animal populations and to be able to house animals in groups without producing additional unwanted offspring. In felids and canids, an association between exposure to progestins and the occurrence of endometrial and mammary gland pathology has been documented. Therefore, the Association of Zoos and Aquariums (AZA) Wildlife Contraceptive Center recommends the use of deslorelin acetate for long-term contraception in carnivores. Return to cyclicity after deslorelin treatment has been variable; some individuals show ovarian suppression for long periods after the expected end of the deslorelin efficacy. In an attempt to reduce the time to reversal, techniques to locate and remove previous implants are being developed. This report documents the successful implementation of high-frequency ultrasonography in lions (Panthera leo) to locate and direct surgical removal of multiple deslorelin implants placed at least 2 yr previously as well as the return of follicular activity in both females at 7 months post-removal of implants.

Depth-resolved cellular microrheology using HiLo microscopy.

PubMed

Michaelson, Jarett; Choi, Heejin; So, Peter; Huang, Hayden

2012-06-01

It is increasingly important to measure cell mechanical properties in three-dimensional environments. Particle tracking microrheology (PTM) can measure cellular viscoelastic properties; however, out-of-plane data can introduce artifacts into these measurements. We developed a technique that employs HiLo microscopy to reduce out-of-plane contributions. This method eliminated signals from 90% of probes 0.5 μm or further from the focal plane, while retaining all in-plane probes. We used this technique to characterize live-cell bilayers and found that there were significant, frequency-dependent changes to the extracted cell moduli when compared to conventional analysis. Our results indicate that removal of out-of-plane information is vital for accurate assessments of cell mechanical properties.

Radiation exposure and performance of multiple burn LEO-GEO orbit transfer trajectories

NASA Technical Reports Server (NTRS)

Gorland, S. H.

1985-01-01

Many potential strategies exist for the transfer of spacecraft from low Earth orbit (LEO) to geosynchronous (GEO) orbit. One strategy has generally been utilized, that being a single impulsive burn at perigee and a GEO insertion burn at apogee. Multiple burn strategies were discussed for orbit transfer vehicles (OTVs) but the transfer times and radiation exposure, particularly for potentially manned missions, were used as arguments against those options. Quantitative results concerning the trip time and radiation encountered by multiple burn orbit transfer missions in order to establish the feasibility of manned missions, the vulnerability of electronics, and the shielding requirements are presented. The performance of these multiple burn missions is quantified in terms of the payload and propellant variances from the minimum energy mission transfer. The missions analyzed varied from one to eight perigee burns and ranged from a high thrust, 1 g acceleration, cryogenic hydrogen-oxygen chemical prpulsion system to a continuous burn, 0.001 g acceleration, hydrogen fueled resistojet propulsion system with a trip time of 60 days.

Retraction of Ross and LoLordo findings concerning blocking in serial feature-positive discriminations.

PubMed

LoLordo, V M; Ross, R T

1990-10-01

Findings concerning the effectiveness of stimuli from various conditioning procedures in blocking conditioned excitation and occasion-setting functions of an added stimulus in a serial feature-postive discrimination training procedure (LoLordo & Ross, 1987; Ross & LoLordo, 1986, 1987) are retracted. Videotapes on which the published data were based were rescored by 2-5 people, most of whom were uninformed about group memberships of the subjects. In no case did the rescoring confirm any of the orginal findings of blocking. Possible factors contributing to the discrepancies are discussed. The experiments should be repeated with feature stimuli that are less similar to each other and with several scorers, at least one of whom is unaware of the group assignment of the subjects.

A metapopulation approach to African lion (Panthera leo) conservation.

PubMed

Dolrenry, Stephanie; Stenglein, Jennifer; Hazzah, Leela; Lutz, R Scott; Frank, Laurence

2014-01-01

Due to anthropogenic pressures, African lion (Panthera leo) populations in Kenya and Tanzania are increasingly limited to fragmented populations. Lions living on isolated habitat patches exist in a matrix of less-preferred habitat. A framework of habitat patches within a less-suitable matrix describes a metapopulation. Metapopulation analysis can provide insight into the dynamics of each population patch in reference to the system as a whole, and these analyses often guide conservation planning. We present the first metapopulation analysis of African lions. We use a spatially-realistic model to investigate how sex-biased dispersal abilities of lions affect patch occupancy and also examine whether human densities surrounding the remaining lion populations affect the metapopulation as a whole. Our results indicate that male lion dispersal ability strongly contributes to population connectivity while the lesser dispersal ability of females could be a limiting factor. When populations go extinct, recolonization will not occur if distances between patches exceed female dispersal ability or if females are not able to survive moving across the matrix. This has profound implications for the overall metapopulation; the female models showed an intrinsic extinction rate from five-fold to a hundred-fold higher than the male models. Patch isolation is a consideration for even the largest lion populations. As lion populations continue to decline and with local extinctions occurring, female dispersal ability and the proximity to the nearest lion population are serious considerations for the recolonization of individual populations and for broader conservation efforts.

A Metapopulation Approach to African Lion (Panthera leo) Conservation

PubMed Central

Dolrenry, Stephanie; Stenglein, Jennifer; Hazzah, Leela; Lutz, R. Scott; Frank, Laurence

2014-01-01

Due to anthropogenic pressures, African lion (Panthera leo) populations in Kenya and Tanzania are increasingly limited to fragmented populations. Lions living on isolated habitat patches exist in a matrix of less-preferred habitat. A framework of habitat patches within a less-suitable matrix describes a metapopulation. Metapopulation analysis can provide insight into the dynamics of each population patch in reference to the system as a whole, and these analyses often guide conservation planning. We present the first metapopulation analysis of African lions. We use a spatially-realistic model to investigate how sex-biased dispersal abilities of lions affect patch occupancy and also examine whether human densities surrounding the remaining lion populations affect the metapopulation as a whole. Our results indicate that male lion dispersal ability strongly contributes to population connectivity while the lesser dispersal ability of females could be a limiting factor. When populations go extinct, recolonization will not occur if distances between patches exceed female dispersal ability or if females are not able to survive moving across the matrix. This has profound implications for the overall metapopulation; the female models showed an intrinsic extinction rate from five-fold to a hundred-fold higher than the male models. Patch isolation is a consideration for even the largest lion populations. As lion populations continue to decline and with local extinctions occurring, female dispersal ability and the proximity to the nearest lion population are serious considerations for the recolonization of individual populations and for broader conservation efforts. PMID:24505385

LoFEx - A local framework for calculating excitation energies: Illustrations using RI-CC2 linear response theory.

PubMed

Baudin, Pablo; Kristensen, Kasper

2016-06-14

We present a local framework for the calculation of coupled cluster excitation energies of large molecules (LoFEx). The method utilizes time-dependent Hartree-Fock information about the transitions of interest through the concept of natural transition orbitals (NTOs). The NTOs are used in combination with localized occupied and virtual Hartree-Fock orbitals to generate a reduced excitation orbital space (XOS) specific to each transition where a standard coupled cluster calculation is carried out. Each XOS is optimized to ensure that the excitation energies are determined to a predefined precision. We apply LoFEx in combination with the RI-CC2 model to calculate the lowest excitation energies of a set of medium-sized organic molecules. The results demonstrate the black-box nature of the LoFEx approach and show that significant computational savings can be gained without affecting the accuracy of CC2 excitation energies.

Thymoquinone suppresses migration of LoVo human colon cancer cells by reducing prostaglandin E2 induced COX-2 activation.

PubMed

Hsu, Hsi-Hsien; Chen, Ming-Cheng; Day, Cecilia Hsuan; Lin, Yueh-Min; Li, Shin-Yi; Tu, Chuan-Chou; Padma, Viswanadha Vijaya; Shih, Hui-Nung; Kuo, Wei-Wen; Huang, Chih-Yang

2017-02-21

To identify potential anti-cancer constituents in natural extracts that inhibit cancer cell growth and migration. Our experiments used high dose thymoquinone (TQ) as an inhibitor to arrest LoVo (a human colon adenocarcinoma cell line) cancer cell growth, which was detected by cell proliferation assay and immunoblotting assay. Low dose TQ did not significantly reduce LoVo cancer cell growth. Cyclooxygenase 2 (COX-2) is an enzyme that is involved in the conversion of arachidonic acid into prostaglandin E2 (PGE2) in humans. PGE2 can promote COX-2 protein expression and tumor cell proliferation and was used as a control. Our results showed that 20 μmol/L TQ significantly reduced human LoVo colon cancer cell proliferation. TQ treatment reduced the levels of p-PI3K, p-Akt, p-GSK3β, and β-catenin and thereby inhibited the downstream COX-2 expression. Results also showed that the reduction in COX-2 expression resulted in a reduction in PGE2 levels and the suppression of EP2 and EP4 activation. Further analysis showed that TG treatment inhibited the nuclear translocation of β-catenin in LoVo cancer cells. The levels of the cofactors LEF-1 and TCF-4 were also decreased in the nucleus following TQ treatment in a dose-dependent manner. Treatment with low dose TQ inhibited the COX-2 expression at the transcriptional level and the regulation of COX-2 expression efficiently reduced LoVo cell migration. The results were further verified in vivo by confirming the effects of TQ and/or PGE2 using tumor xenografts in nude mice. TQ inhibits LoVo cancer cell growth and migration, and this result highlights the therapeutic advantage of using TQ in combination therapy against colorectal cancer.

Three dimensional HiLo-based structured illumination for a digital scanned laser sheet microscopy (DSLM) in thick tissue imaging.

PubMed

Bhattacharya, Dipanjan; Singh, Vijay Raj; Zhi, Chen; So, Peter T C; Matsudaira, Paul; Barbastathis, George

2012-12-03

Laser sheet based microscopy has become widely accepted as an effective active illumination method for real time three-dimensional (3D) imaging of biological tissue samples. The light sheet geometry, where the camera is oriented perpendicular to the sheet itself, provides an effective method of eliminating some of the scattered light and minimizing the sample exposure to radiation. However, residual background noise still remains, limiting the contrast and visibility of potentially interesting features in the samples. In this article, we investigate additional structuring of the illumination for improved background rejection, and propose a new technique, "3D HiLo" where we combine two HiLo images processed from orthogonal directions to improve the condition of the 3D reconstruction. We present a comparative study of conventional structured illumination based demodulation methods, namely 3Phase and HiLo with a newly implemented 3D HiLo approach and demonstrate that the latter yields superior signal-to-background ratio in both lateral and axial dimensions, while simultaneously suppressing image processing artifacts.

Lava bubble-wall fragments formed by submarine hydrovolcanic explosions on Lo'ihi Seamount and Kilauea Volcano

USGS Publications Warehouse

Clague, D.A.; Davis, A.S.; Bischoff, J.L.; Dixon, J.E.; Geyer, R.

2000-01-01

Glassy bubble-wall fragments, morphologically similar to littoral limu o Pele, have been found in volcanic sands erupted on Lo'ihi Seamount and along the submarine east rift zone of Kilauea Volcano. The limu o Pele fragments are undegassed with respect to H2O and S and formed by mild steam explosions. Angular glass sand fragments apparently form at similar, and greater, depths by cooling-contraction granulation. The limu o Pele fragments from Lo'ihi Seamount are dominantly tholeiitic basalt containing 6.25-7.25% MgO. None of the limu o Pele samples from Lo'ihi Seamount contains less than 5.57% MgO, suggesting that higher viscosity magmas do not form lava bubbles. The dissolved CO2 and H2O contents of 7 of the limu o Pele fragments indicate eruption at 1200??300 m depth (120??30 bar). These pressures exceed that generally thought to limit steam explosions. We conclude that hydrovolcanic eruptions are possible, with appropriate pre-mixing conditions, at pressures as great as 120 bar.

DIAGNOSIS AND TREATMENT OF A UNILATERAL RENAL CYSTADENOMA IN AN AFRICAN LION (PANTHERA LEO).

PubMed

Eustace, Ronan; Rubin, Jacob; Thompson, Kimberly A; Snowdon, Kyle; Sikarskie, James G; Monahan, Colleen; Smedley, Rebecca C

2017-09-01

A renal tubular cystadenoma was diagnosed in a 14-yr-old male African lion (Panthera leo). During a routine health evaluation, a left renal mass was identified via physical examination, radiographs, and abdominal ultrasonography. The mass was 30 × 15 cm in size and had a thin capsule with central hypoechoic fluid, suggestive of a perirenal cyst. An exploratory celiotomy with partial nephrectomy was performed without complications. Histologically, the tumor was characterized by a thick fibrous capsule surrounding multiple, variable-sized cysts that markedly compressed the adjacent fibrotic and atrophied renal cortex. Immunohistochemical labeling for Aquaporin-1 and Tamm-Horsfall protein was consistent with a renal tubular cystadenoma of proximal tubule origin. Renal cystadenomas are an uncommon benign epithelial neoplasm. There are only two documented case reports in domestic cats. This report represents the first documentation, to the authors' knowledge, of a renal cystadenoma in a lion.

Cefovecin (Convenia) for the treatment of septic peritonitis in a female lion (Panthera leo).

PubMed

Steeil, James; Schumacher, Juergen; Seibert, Rachel; Tobias, Karen

2012-09-01

An 8-yr-old intact female African lion (Panthera leo) presented with a 3-day history of lethargy, anorexia, and vomiting. Hematologic and biochemical abnormalities included a leukocytosis, 41,700/microl (4,700-15,300) with a neutrophilia (37,530/microl; 2,000-9,200) and a left shift (1,250/microl bands; 0-300), and mild hypokalemia of 2.1 mEq/L (2.8-4.8). Abdominal radiographs revealed evidence of intestinal ileus, peritonitis, and the presence of effusion. An exploratory laparotomy was performed, and septic peritonitis due to a pyometra was diagnosed. The lion was treated with an ovariohysterectomy, abdominal lavage, fluid therapy, and a subcutaneous injection of cefovecin. The lion recovered, and clinical signs associated with septic peritonitis resolved within 36 hr. It was returned to conspecifics 3 wk later. Three months postoperatively, the lion showed no residual signs of septic peritonitis.

Responsivity calibration of the LoWEUS spectrometer

DOE PAGES

Lepson, J. K.; Beiersdorfer, P.; Kaita, R.; ...

2016-09-02

We performed an in situ calibration of the relative responsivity function of the Long-Wavelength Extreme Ultraviolet Spectrometer (LoWEUS), while operating on the Lithium Tokamak Experiment (LTX) at Princeton Plasma Physics Laboratory. The calibration was accomplished by measuring oxygen lines, which are typically present in LTX plasmas. The measured spectral line intensities of each oxygen charge state were then compared to the calculated emission strengths given in the CHIANTI atomic database. Normalizing the strongest line in each charge state to the CHIANTI predictions, we obtained the differences between the measured and predicted values for the relative strengths of the other linesmore » of a given charge state. We find that a 3rd degree polynomial function provides a good fit to the data points. Lastly, our measurements show that the responsivity between about 120 and 300 Å varies by factor of ~30.« less

Depth-resolved cellular microrheology using HiLo microscopy

PubMed Central

Michaelson, Jarett; Choi, Heejin; So, Peter; Huang, Hayden

2012-01-01

It is increasingly important to measure cell mechanical properties in three-dimensional environments. Particle tracking microrheology (PTM) can measure cellular viscoelastic properties; however, out-of-plane data can introduce artifacts into these measurements. We developed a technique that employs HiLo microscopy to reduce out-of-plane contributions. This method eliminated signals from 90% of probes 0.5 μm or further from the focal plane, while retaining all in-plane probes. We used this technique to characterize live-cell bilayers and found that there were significant, frequency-dependent changes to the extracted cell moduli when compared to conventional analysis. Our results indicate that removal of out-of-plane information is vital for accurate assessments of cell mechanical properties. PMID:22741071

Congenital biliary tract malformation resembling biliary cystadenoma in a captive juvenile African lion (Panthera leo).

PubMed

Caliendo, Valentina; Bull, Andrew C J; Stidworthy, Mark F

2012-12-01

A captive 3-mo-old white African lion (Panthera leo) presented with clinical signs of acute pain and a distended abdomen. Despite emergency treatment, the lion died a few hours after presentation. Postmortem examination revealed gross changes in the liver, spleen, and lungs and an anomalous cystic structure in the bile duct. Histologic examination identified severe generalized multifocal to coalescent necrotizing and neutrophilic hepatitis, neutrophilic splenitis, and mild interstitial pneumonia, consistent with bacterial septicemia. The abnormal biliary structures resembled biliary cystadenoma. However, due to the age of the animal, they were presumed to be congenital in origin. Biliary tract anomalies and cystadenomas have been reported previously in adult lions, and this case suggests that at least some of these examples may have a congenital basis. It is unclear whether the lesion was an underlying factor in the development of hepatitis.

Double aortic arch and persistent left vena cava in a white lion cub (Panthera leo).

PubMed

Goldin, J P; Lambrechts, N E

1999-03-01

A 4-mo-old female white lion (Panthera leo) cub was presented with a 2-wk history of persistent postprandial regurgitation, mild dyspnea, and poor weight gain. The cub was weak and thin but otherwise alert. Survey and contrast radiography revealed a large dilated esophagus cranial to the heart base, with an esophageal filling defect present at the level of the fourth thoracic vertebra. A vascular ring anomaly was tentatively diagnosed. Exploratory thoracotomy revealed a double aortic arch and a persistent left vena cava. The left aortic arch was ligated and divided, and recovery was uneventful. A single episode of regurgitation occurred within the first postoperative month, and the cub gained 5.5 kg in weight during the same time period. Neither double aortic arch nor persistent left vena cava has been reported in a nondomestic felid.

5-LO inhibition ameliorates palmitic acid-induced ER stress, oxidative stress and insulin resistance via AMPK activation in murine myotubes.

PubMed

Kwak, Hyun Jeong; Choi, Hye-Eun; Cheon, Hyae Gyeong

2017-07-10

Leukotriene B4 (LTB4) production via the 5-lipoxygenase (5-LO) pathway contributes to the development of insulin resistance in adipose and hepatic tissues, but the role of LTB4 in skeletal muscle is relatively unknown. Here, the authors investigated the role of LTB4 in C2C12 myotubes in palmitic acid (PA)-induced ER stress, inflammation and insulin resistance. PA (750 μM) evoked lipotoxicity (ER stress, oxidative stress, inflammation and insulin resistance) in association with LTB4 production. 5-LO inhibition reduced all the lipotoxic effects induced by PA. On the other hand, PA did not induce cysteinyl leukotrienes (CysLTs), which themselves had no effect on ER stress and inflammation. The beneficial effects of 5-LO suppression from PA-induced lipotoxicity were related with AMPK activation. In ob/ob mice, once daily oral administration of zileuton (50, 100 mg/kg) for 5 weeks improved insulin resistance, increased AMPK phosphorylation, and reduced LTB4 and ER stress marker expression in skeletal muscle. These results show that 5-LO inhibition by either zileuton or 5-LO siRNA protects C2C12 myotubes from PA-induced lipotoxicity, at least partly via AMPK activation, and suggest that the in vivo insulin-sensitizing effects of zileuton are in part attributable to its direct action on skeletal muscle via LTB4 downregulation followed by AMPK activation.

Scanning light-sheet microscopy in the whole mouse brain with HiLo background rejection

PubMed Central

Mertz, Jerome; Kim, Jinhyun

2010-01-01

It is well known that light-sheet illumination can enable optically sectioned wide-field imaging of macroscopic samples. However, the optical sectioning capacity of a light-sheet macroscope is undermined by sample-induced scattering or aberrations that broaden the thickness of the sheet illumination. We present a technique to enhance the optical sectioning capacity of a scanning light-sheet microscope by out-of-focus background rejection. The technique, called HiLo microscopy, makes use of two images sequentially acquired with uniform and structured sheet illumination. An optically sectioned image is then synthesized by fusing high and low spatial frequency information from both images. The benefits of combining light-sheet macroscopy and HiLo background rejection are demonstrated in optically cleared whole mouse brain samples, using both green fluorescent protein (GFP)-fluorescence and dark-field scattered light contrast. PMID:20210471

Scanning light-sheet microscopy in the whole mouse brain with HiLo background rejection.

PubMed

Mertz, Jerome; Kim, Jinhyun

2010-01-01

It is well known that light-sheet illumination can enable optically sectioned wide-field imaging of macroscopic samples. However, the optical sectioning capacity of a light-sheet macroscope is undermined by sample-induced scattering or aberrations that broaden the thickness of the sheet illumination. We present a technique to enhance the optical sectioning capacity of a scanning light-sheet microscope by out-of-focus background rejection. The technique, called HiLo microscopy, makes use of two images sequentially acquired with uniform and structured sheet illumination. An optically sectioned image is then synthesized by fusing high and low spatial frequency information from both images. The benefits of combining light-sheet macroscopy and HiLo background rejection are demonstrated in optically cleared whole mouse brain samples, using both green fluorescent protein (GFP)-fluorescence and dark-field scattered light contrast.

Scanning light-sheet microscopy in the whole mouse brain with HiLo background rejection

NASA Astrophysics Data System (ADS)

Mertz, Jerome; Kim, Jinhyun

2010-01-01

It is well known that light-sheet illumination can enable optically sectioned wide-field imaging of macroscopic samples. However, the optical sectioning capacity of a light-sheet macroscope is undermined by sample-induced scattering or aberrations that broaden the thickness of the sheet illumination. We present a technique to enhance the optical sectioning capacity of a scanning light-sheet microscope by out-of-focus background rejection. The technique, called HiLo microscopy, makes use of two images sequentially acquired with uniform and structured sheet illumination. An optically sectioned image is then synthesized by fusing high and low spatial frequency information from both images. The benefits of combining light-sheet macroscopy and HiLo background rejection are demonstrated in optically cleared whole mouse brain samples, using both green fluorescent protein (GFP)-fluorescence and dark-field scattered light contrast.

CALCINOSIS CIRCUMSCRIPTA IN A COHORT OF RELATED JUVENILE AFRICAN LIONS (PANTHERA LEO).

PubMed

Bauer, Kendra L; Sander, Samantha J; Steeil, James C; Walsh, Timothy F; Neiffer, Donald L

2017-09-01

Three juvenile, genetically related African lions (Panthera leo) were evaluated for discrete dome-shaped subcutaneous masses present over the proximal lateral metatarsal-tarsal area. The lesions measured 3-8 cm in diameter, were fluctuant to firm, nonulcerated, and attached to underlying structures. On radiographic evaluation, the lesions were characterized by well-circumscribed punctate mineralizations in the soft tissue surrounded by soft tissue swelling without evidence of adjacent bony involvement. On cut surface, the lesions were made of numerous loculi containing 2-5-mm round-to-ovoid, white-to-gray, firm structures interspersed with fibrous tissue and pockets of serosanguinous fluid. Hematology, serum biochemistry, serum thyroid screening (including total thyroxine, total triiodothyronine, free thyroxine, and free triiodothyronine), and serum vitamin D panels (including parathyroid hormone, ionized calcium, and 25-hydroxyvitamin D) were unremarkable. Histopathologic evaluation of the lesions was consistent with calcinosis circumscripta with fibroplasia, chronic inflammation, and seroma formation. An additional two genetically related lions were considered suspect for calcinosis circumscripta based on presentation, exam findings, and similarity to the confirmed cases. All masses self-regressed and were not associated with additional clinical signs other than initial lameness in two cases.

The influence of lunar phases and zodiac sign 'Leo' on perioperative complications and outcome in elective spine surgery.

PubMed

Joswig, Holger; Stienen, Martin N; Hock, Carolin; Hildebrandt, Gerhard; Surbeck, Werner

2016-06-01

Many people believe that the moon has an influence on daily life, and some even request elective surgery dates depending on the moon calendar. The aim of this study was to assess the influence of 'unfavorable' lunar or zodiac constellations on perioperative complications and outcome in elective surgery for degenerative disc disease. Retrospective database analysis including 924 patients. Using uni- and multivariate logistic regression, the likelihood for intraoperative complications and re-do surgeries as well as the clinical outcomes at 4 weeks was analyzed for surgeries performed during the waxing moon, full moon, and dates when the moon passed through the zodiac sign 'Leo.' In multivariate analysis, patients operated on during the waxing moon were 1.54 times as likely as patients who were operated on during the waning moon to suffer from an intraoperative complication (OR 1.54, 95 % CI 1.07-2.21, p = 0.019). In contrast, there was a trend toward fewer re-do surgeries for surgery during the waxing moon (OR 0.51, 95 % CI 0.23-1.16, p = 0.109), while the 4-week responder status was similar (OR 0.73, 95 % CI 0.47-1.14, p = 0.169). A full moon and the zodiac sign Leo did not increase the likelihood for complications, re-do surgeries or unfavorable outcomes. We found no influence of 'unfavorable' lunar or zodiac constellations on the 4-week responder status or the revision rate that would justify a moon calendar-based selection approach to elective spine surgery dates. However, the fact that patients undergoing surgery during the waxing moon were more likely to suffer from an intraoperative complication is a surprising curiosity and defies our ability to find a rational explanation.

N3LO corrections to jet production in deep inelastic scattering using the Projection-to-Born method

NASA Astrophysics Data System (ADS)

Currie, J.; Gehrmann, T.; Glover, E. W. N.; Huss, A.; Niehues, J.; Vogt, A.

2018-05-01

Computations of higher-order QCD corrections for processes with exclusive final states require a subtraction method for real-radiation contributions. We present the first-ever generalisation of a subtraction method for third-order (N3LO) QCD corrections. The Projection-to-Born method is used to combine inclusive N3LO coefficient functions with an exclusive second-order (NNLO) calculation for a final state with an extra jet. The input requirements, advantages, and potential applications of the method are discussed, and validations at lower orders are performed. As a test case, we compute the N3LO corrections to kinematical distributions and production rates for single-jet production in deep inelastic scattering in the laboratory frame, and compare them with data from the ZEUS experiment at HERA. The corrections are small in the central rapidity region, where they stabilize the predictions to sub per-cent level. The corrections increase substantially towards forward rapidity where large logarithmic effects are expected, thereby yielding an improved description of the data in this region.

CXCR6 marks a novel subset of T-bet(lo)Eomes(hi) natural killer cells residing in human liver.

PubMed

Stegmann, Kerstin A; Robertson, Francis; Hansi, Navjyot; Gill, Upkar; Pallant, Celeste; Christophides, Theodoros; Pallett, Laura J; Peppa, Dimitra; Dunn, Claire; Fusai, Giuseppe; Male, Victoria; Davidson, Brian R; Kennedy, Patrick; Maini, Mala K

2016-05-23

Natural killer cells (NK) are highly enriched in the human liver, where they can regulate immunity and immunopathology. We probed them for a liver-resident subset, distinct from conventional bone-marrow-derived NK. CXCR6+ NK were strikingly enriched in healthy and diseased liver compared to blood (p < 0.0001). Human hepatic CXCR6+ NK had an immature phenotype (predominantly CD56(bright)CD16-CD57-), and expressed the tissue-residency marker CD69. CXCR6+ NK produced fewer cytotoxic mediators and pro-inflammatory cytokines than the non-liver-specific CXCR6- fraction. Instead CXCR6+ NK could upregulate TRAIL, a key death ligand in hepatitis pathogenesis. CXCR6 demarcated liver NK into two transcriptionally distinct populations: T-bet(hi)Eomes(lo)(CXCR6-) and T-bet(lo)Eomes(hi)(CXCR6+); the latter was virtually absent in the periphery. The small circulating CXCR6+ subset was predominantly T-bet(hi)Eomes(lo), suggesting its lineage was closer to CXCR6- peripheral than CXCR6+ liver NK. These data reveal a large subset of human liver-resident T-bet(lo)Eomes(hi) NK, distinguished by their surface expression of CXCR6, adapted for hepatic tolerance and inducible anti-viral immunity.

Circulating CXCR5+CXCR3+PD-1lo Tfh-like cells in HIV-1 controllers with neutralizing antibody breadth

PubMed Central

Martin-Gayo, Enrique; Cronin, Jacqueline; Hickman, Taylor; Ouyang, Zhengyu; Lindqvist, Madelene; Kolb, Kellie E.; Schulze zur Wiesch, Julian; Cubas, Rafael; Porichis, Filippos; Shalek, Alex K.; van Lunzen, Jan; Haddad, Elias K.; Walker, Bruce D.; Kaufmann, Daniel E.; Lichterfeld, Mathias; Yu, Xu G.

2017-01-01

HIV-1–specific broadly neutralizing antibodies (bnAbs) typically develop in individuals with continuous high-level viral replication and increased immune activation, conditions that cannot be reproduced during prophylactic immunization. Understanding mechanisms supporting bnAb development in the absence of high-level viremia may be important for designing bnAb-inducing immunogens. Here, we show that the breadth of neutralizing antibody responses in HIV-1 controllers was associated with a relative enrichment of circulating CXCR5+CXCR3+PD-1lo CD4+ T cells. These CXCR3+PD-1lo Tfh-like cells were preferentially induced in vitro by functionally superior dendritic cells from controller neutralizers, and able to secrete IL-21 and support B cells. In addition, these CXCR3+PD-1lo Tfh-like cells contained higher proportions of stem cell–like memory T cells, and upon antigenic stimulation differentiated into PD-1hi Tfh-like cells in a Notch-dependent manner. Together, these data suggest that CXCR5+CXCR3+PD-1lo cells represent a dendritic cell–primed precursor cell population for PD-1hi Tfh-like cells that may contribute to the generation of bnAbs in the absence of high-level viremia. PMID:28138558

A Hubble Space Telescope imaging study of four FeLoBAL quasar host galaxies

NASA Astrophysics Data System (ADS)

Lawther, D.; Vestergaard, M.; Fan, X.

2018-04-01

We study the host galaxies of four Iron Low-Ionization Broad Absorption-line Quasars (FeLoBALs), using Hubble Space Telescope imaging data, investigating the possibility that they represent a transition between an obscured active galactic nucleus (AGN) and an ordinary optical quasar. In this scenario, the FeLoBALs represent the early stage of merger-triggered accretion, in which case their host galaxies are expected to show signs of an ongoing or recent merger. Using PSF subtraction techniques, we decompose the images into host galaxy and AGN components at rest-frame ultraviolet and optical wavelengths. The ultraviolet is sensitive to young stars, while the optical probes stellar mass. In the ultraviolet we image at the BAL absorption trough wavelengths so as to decrease the contrast between the quasar and host galaxy emission. We securely detect an extended source for two of the four FeLoBALs in the rest-frame optical; a third host galaxy is marginally detected. In the rest-frame UV we detect no host emission; this constrains the level of unobscured star formation. Thus, the host galaxies have observed properties that are consistent with those of non-BAL quasars with the same nuclear luminosity, i.e. quiescent or moderately star-forming elliptical galaxies. However, we cannot exclude starbursting hosts that have the stellar UV emission obscured by modest amounts of dust reddening. Thus, our findings also allow the merger-induced young quasar scenario. For three objects, we identify possible close companion galaxies that may be gravitationally interacting with the quasar hosts.

Higher Order Corrections in the CoLoRFulNNLO Framework

NASA Astrophysics Data System (ADS)

Somogyi, G.; Kardos, A.; Szőr, Z.; Trócsányi, Z.

We discuss the CoLoRFulNNLO method for computing higher order radiative corrections to jet cross sections in perturbative QCD. We apply our method to the calculation of event shapes and jet rates in three-jet production in electron-positron annihilation. We validate our code by comparing our predictions to previous results in the literature and present the jet cone energy fraction distribution at NNLO accuracy. We also present preliminary NNLO results for the three-jet rate using the Durham jet clustering algorithm matched to resummed predictions at NLL accuracy, and a comparison to LEP data.

The AhR is involved in the regulation of LoVo cell proliferation through cell cycle-associated proteins.

PubMed

Yin, Jiuheng; Sheng, Baifa; Han, Bin; Pu, Aimin; Yang, Kunqiu; Li, Ping; Wang, Qimeng; Xiao, Weidong; Yang, Hua

2016-05-01

Some ingredients in foods can activate the aryl hydrocarbon receptor (AhR) and arrest cell proliferation. In this study, we hypothesized that 6-formylindolo [3, 2-b] carbazole (FICZ) arrests the cell cycle in LoVo cells (a colon cancer line) through the AhR. The AhR agonist FICZ and the AhR antagonist CH223191 were used to treat LoVo cells. Real-time PCR and Western blot analyses were performed to detect the expression of the AhR, CYP1A1, CDK4, cyclinD1, cyclin E, CDK2, P27, and pRb. The distribution and activation of the AhR were detected with immunofluorescence. A 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide (MTT) assay and flow cytometric analysis were performed to measure cell viability, cell cycle stage, and apoptosis. Our results show that FICZ inhibited LoVo cell proliferation by inducing G1 cell cycle arrest but had no effect on epithelial apoptosis. Further analysis found that FICZ downregulated cyclinD1 and upregulated p27 expression to arrest Rb phosphorylation. The downregulation of cyclinD1 and upregulation of p27 were abolished by co-treatment with CH223191. We conclude that the AhR, when activated by FICZ (an endogenous AhR ligand), can arrest the cell cycle and block LoVo cell proliferation. © 2016 International Federation for Cell Biology.

Column-like EED extending from equatorial topside ionosphere toward plasmasphere retrieved from IGS and LEO/GPS observations with 3-D CT inversion

NASA Astrophysics Data System (ADS)

Xiao, R.; Ma, S. Y.; Xu, J. S.; Xiong, C.; Luehr, H.; Jakowski, N.

2010-05-01

The electron density distributions in the equatorial ionosphere are retrieved from GPS observations of joint ground-based IGS and onboard CHAMP/GRACE satellites during November 2004 super-storm by 3-D tomography technique. For LEO satellite-based GPS receiving, both the occultation TEC data and that along the radio propagation paths above the LEO are used and assimilated into the huge IGS TEC dataset. The electron density images are reconstructed for different sectors of America, Asia and Europe and produced for every hour. The retrieved electron densities are validated by satellite in situ measurements of CHAMP Langmuir probe and GRACE Ka-band SST (low-low satellite-to-satellite tracking) derived electron density averaged between the two satellites, as well as by numerical simulations. It reveals some very interesting storm-time structures of Ne distributions, such as top-hat-like F2-3 double layer and column-like enhanced electron densities (CEED). The CEED are found during the main phase of the storm near the minimum of Dst and in the longitudinal sector centered at 157E. They extend from the topside ionosphere toward to plasmasphere, reaching at least about 2000 km as high. The footprints of the CEED stand on the two peaks of the EIA. The forming mechanism of CEED and its relationship with SED and plasmaspheric plumes are worthy of further study. This work is supported by NSFC (No.40674078).

Establishing an Appropriate Level of Detail (LoD) for a Building Information Model (BIM) - West Block, Parliament Hill, Ottawa, Canada

NASA Astrophysics Data System (ADS)

Fai, S.; Rafeiro, J.

2014-05-01

In 2011, Public Works and Government Services Canada (PWGSC) embarked on a comprehensive rehabilitation of the historically significant West Block of Canada's Parliament Hill. With over 17 thousand square meters of floor space, the West Block is one of the largest projects of its kind in the world. As part of the rehabilitation, PWGSC is working with the Carleton Immersive Media Studio (CIMS) to develop a building information model (BIM) that can serve as maintenance and life-cycle management tool once construction is completed. The scale and complexity of the model have presented many challenges. One of these challenges is determining appropriate levels of detail (LoD). While still a matter of debate in the development of international BIM standards, LoD is further complicated in the context of heritage buildings because we must reconcile the LoD of the BIM with that used in the documentation process (terrestrial laser scan and photogrammetric survey data). In this paper, we will discuss our work to date on establishing appropriate LoD within the West Block BIM that will best serve the end use. To facilitate this, we have developed a single parametric model for gothic pointed arches that can be used for over seventy-five unique window types present in the West Block. Using the AEC (CAN) BIM as a reference, we have developed a workflow to test each of these window types at three distinct levels of detail. We have found that the parametric Gothic arch significantly reduces the amount of time necessary to develop scenarios to test appropriate LoD.

Functional characterization of ExFadLO, an outer membrane protein required for exporting oxygenated long-chain fatty acids in Pseudomonas aeruginosa.

PubMed

Martínez, Eriel; Estupiñán, Mónica; Pastor, F I Javier; Busquets, Montserrat; Díaz, Pilar; Manresa, Angeles

2013-02-01

Bacterial proteins of the FadL family have frequently been associated to the uptake of exogenous hydrophobic substrates. However, their outer membrane location and involvement in substrate uptake have been inferred mainly from sequence similarity to Escherichia coli FadL, the first well-characterized outer membrane transporters of Long-Chain Fatty Acids (LCFAs) in bacteria. Here we report the functional characterization of a Pseudomonas aeruginosa outer membrane protein (ORF PA1288) showing similarities to the members of the FadL family, for which we propose the name ExFadLO. We demonstrate herein that this protein is required to export LCFAs 10-HOME and 7,10-DiHOME, derived from a diol synthase oxygenation activity on oleic acid, from the periplasm to the extracellular medium. Accumulation of 10-HOME and 7,10-DiHOME in the extracellular medium of P. aeruginosa was abolished by a transposon insertion mutation in exFadLO (ExFadLO¯ mutant). However, intact periplasm diol synthase activity was found in this mutant, indicating that ExFadLO participates in the export of these oxygenated LCFAs across the outer membrane. The capacity of ExFadLO¯ mutant to export 10-HOME and 7,10-DiHOME was recovered after complementation with a wild-type, plasmid-expressed ExFadLO protein. A western blot assay with a variant of ExFadLO tagged with a V5 epitope confirmed the location of ExFadLO in the bacterial outer membrane under the experimental conditions tested. Our results provide the first evidence that FadL family proteins, known to be involved in the uptake of hydrophobic substrates from the extracellular environment, also function as secretion elements for metabolites of biological relevance. Copyright © 2012 Elsevier Masson SAS. All rights reserved.

Soft Expansion of Double-Real-Virtual Corrections to Higgs Production at N$^3$LO

DOE PAGES

Anastasiou, Charalampos; Duhr, Claude; Dulat, Falko; ...

2015-05-15

We present methods to compute higher orders in the threshold expansion for the one-loop production of a Higgs boson in association with two partons at hadron colliders. This process contributes to the N 3LO Higgs production cross section beyond the soft-virtual approximation. We use reverse unitarity to expand the phase-space integrals in the small kinematic parameters and to reduce the coefficients of the expansion to a small set of master integrals. We describe two methods for the calculation of the master integrals. The first was introduced for the calculation of the soft triple-real radiation relevant to N 3LO Higgs production.more » The second uses a particular factorization of the three body phase-space measure and the knowledge of the scaling properties of the integral itself. Our result is presented as a Laurent expansion in the dimensional regulator, although some of the master integrals are computed to all orders in this parameter.« less

Pavement crack detection combining non-negative feature with fast LoG in complex scene

NASA Astrophysics Data System (ADS)

Wang, Wanli; Zhang, Xiuhua; Hong, Hanyu

2015-12-01

Pavement crack detection is affected by much interference in the realistic situation, such as the shadow, road sign, oil stain, salt and pepper noise etc. Due to these unfavorable factors, the exist crack detection methods are difficult to distinguish the crack from background correctly. How to extract crack information effectively is the key problem to the road crack detection system. To solve this problem, a novel method for pavement crack detection based on combining non-negative feature with fast LoG is proposed. The two key novelties and benefits of this new approach are that 1) using image pixel gray value compensation to acquisit uniform image, and 2) combining non-negative feature with fast LoG to extract crack information. The image preprocessing results demonstrate that the method is indeed able to homogenize the crack image with more accurately compared to existing methods. A large number of experimental results demonstrate the proposed approach can detect the crack regions more correctly compared with traditional methods.

Mucoperiosteal exostoses in the tympanic bulla of African lions (Panthera leo).

PubMed

Novales, M; Ginel, P J; Diz, A; Blanco, B; Zafra, R; Guerra, R; Mozos, E

2015-03-01

Mucoperiosteal exostoses (MpEs) of the tympanic bulla (TB), also referred as middle-ear otoliths, have been occasionally described in dogs and cats in association with clinical signs of otitis media or as an incidental finding, but they have not been recorded in other species. In this report, we describe the radiographic, gross, and histopathologic features of MpEs in 8 African lions (Panthera leo). All animals (5 males and 3 females) were adults that had been kept in captivity and had their skeletons conserved as part of an anatomic academic collection. A radiographic study revealed mineralized structures in the TB consistent with MpEs in 7 of the 16 examined TB; a computed tomography study identified MpEs in 12 of the 16 TB. Six TB from 4 lions were sectioned, and several MpEs were demineralized for histopathologic analysis. Grossly, MpEs appeared variable in number and shape. Some were globular structures that were loosely attached to the mucosal surface of the TB; others were isolated to coalescent bone spicules extending from the mucoperiosteum. Position was also variable, but MpEs frequently developed in the hypotympanum, especially on the ventromedial aspect of the TB wall. Microscopically, MpEs were composed of osteonal bone growing from the periosteum and not by dystrophic calcification of necrotic tissue debris, as is hypothesized in dogs. © The Author(s) 2014.

Future orbital transfer vehicle technology study. Volume 2: Technical report

NASA Technical Reports Server (NTRS)

Davis, E. E.

1982-01-01

Missions for future orbit transfer vehicles (1995-2010) are identified and the technology, operations and vehicle concepts that satisfy the transportation requirements are defined. Comparison of reusable space and ground based LO2/LH2 OTV's was made. Both vehicles used advanced space engines and aero assist capability. The SB OTV provided advantages in life cycle cost, performance and potential for improvement. Comparison of an all LO2/LH2 OTV fleet with a fleet of LO2/LH2 OTVs and electric OTV's was also made. The normal growth technology electric OTV used silicon cells with heavy shielding and argon ion thrusters. This provided a 23% advantage in total transportation cost. The impact of accelerated technology was considered in terms of improvements in performance and cost effectiveness. The accelerated technology electric vehicle used GaAs cells and annealing but did not result in the mixed fleet being any cheaper than an all LO2/LH2 OTV fleet. It is concluded that reusable LO2/LH2 OTV's can serve all general purpose cargo roles between LEO and GEO for the forseeable future. The most significant technology for the second generation vehicle would be space debris protection, on-orbit propellant storage and transfer and on-orbit maintenance capability.

The inhibition of 5-Lipoxygenase (5-LO) products leukotriene B4 (LTB4) and cysteinyl leukotrienes (cysLTs) modulates the inflammatory response and improves cutaneous wound healing.

PubMed

Guimarães, Francielle Rodrigues; Sales-Campos, Helioswilton; Nardini, Viviani; da Costa, Thiago Alvares; Fonseca, Monique Thaís Costa; Júnior, Virmondes Rodrigues; Sorgi, Carlos Artério; da Silva, João Santana; Chica, Javier Emílio Lazo; Faccioli, Lúcia Helena; de Barros Cardoso, Cristina Ribeiro

2018-05-01

To analyze the participation of the enzyme 5-lipoxygenase (5-LO) in skin repair, WT wounds were compared to those in 5-LO deficient mice (5-LO -/- ), which presented faster closure and reduced inflammatory infiltrate in the skin, together with increased CD4 regulatory T cells markers in the draining lymph nodes. The 5-LO -/- wounds also had diminished TNF-α, CCL11, CCL7, CCL2, CXCL9, CCR1 and CXCR2 mRNA expression in the lesions, besides differential extracellular matrix remodeling. Furthermore, when cysteinyl leukotriene (cysLT) and leukotriene (LTB 4 ) receptors were antagonized in WT mice, there was a remarkable reduction in TNF-α expression and faster skin healing, similarly to the findings in 5-LO -/- animals. Finally, our results suggested that 5-LO products, in special cysLT and LTB 4 , underline skin inflammation that follows skin injury and their neutralization may be an important strategy to improve cutaneous healing. Copyright © 2017 Elsevier Inc. All rights reserved.

Molecular characterization of Hepatozoon felis in Rhipicephalus sanguineus ticks infested on captive lions (Panthera leo).

PubMed

Bhusri, Benjaporn; Sariya, Ladawan; Mongkolphan, Chalisa; Suksai, Parut; Kaewchot, Supakarn; Changbunjong, Tanasak

2017-09-01

Hepatozoon spp. are protozoan parasites that infect a wide range of domestic and wild animals. The infection occurs by ingestion of an infected tick. This study was carried out to detect and characterize Hepatozoon spp. in ticks collected from captive lions ( Panthera leo ) in Thailand based on the partial 18S rRNA gene sequence. A total of 30 ticks were collected and identified as Rhipicephalus sanguineus . The collected ticks were separated into 10 tick pools by sex and life stages. Of the 10 tick pools examined, only one (10%) was found to be infected with the Hepatozoon species. Sequencing and phylogenetic analysis showed a clustering of the partial 18S rRNA gene sequence like that of H. felis from the GenBank database. This is the first report of H. felis in R. sanguineus ticks collected from captive lions in Thailand. Our results indicated that R. sanguineus may be a possible vector of feline Hepatozoon in Thailand.

Benton Judgment of Line Orientation (JoLO) Test: A Brief and Useful Measure for Assessing Visuospatial Abilities in Manifest, but not Premanifest, Huntington's Disease.

PubMed

Corey-Bloom, Jody; Gluhm, Shea; Herndon, Andrew; Haque, Ameera S; Park, Sungmee; Gilbert, Paul E

2016-01-01

Visuospatial deficits have been described in Huntington's disease (HD); however, the extent of these deficits remains unclear. The Benton Judgment of Line Orientation (JoLO) Test, commonly used to assess visuospatial ability, requires minimal motor involvement. It has demonstrated sensitivity to visuospatial deficits in Parkinson's disease; however, few studies have examined performance on this test in HD. The objective of the current study was to assess visuospatial ability in premanifest and manifest HD using the JoLO. A global cognitive measure, the Mattis Dementia Rating Scale (DRS), was used to stratify manifest HD patients as mild (DRS ≥129) vs. moderate-severe (DRS ≤128). Fifty mild, 42 moderate-severe, and 30 premanifest HD subjects, as well as 35 matched controls, were administered the JoLO. HD Burden of Pathology (BOP) scores were used as a measure of disease severity. Results revealed that the total manifest HD sample (p <  0.001), in addition to the mild (p = 0.028), and moderate-severe (p <  0.001), but not premanifest, HD subjects scored significantly lower on the JoLO compared to normal controls. Our results suggest that the JoLO is useful for detecting visuospatial deficits across various stages of manifest HD. However, any visuospatial impairment that might be present during the premanifest stage of HD was not detected using the JoLO in the present sample.

Lions (Panthera leo) solve, learn, and remember a novel resource acquisition problem.

PubMed

Borrego, Natalia; Dowling, Brian

2016-09-01

The social intelligence hypothesis proposes that the challenges of complex social life bolster the evolution of intelligence, and accordingly, advanced cognition has convergently evolved in several social lineages. Lions (Panthera leo) offer an ideal model system for cognitive research in a highly social species with an egalitarian social structure. We investigated cognition in lions using a novel resource task: the suspended puzzle box. The task required lions (n = 12) to solve a novel problem, learn the techniques used to solve the problem, and remember techniques for use in future trials. The majority of lions demonstrated novel problem-solving and learning; lions (11/12) solved the task, repeated success in multiple trials, and significantly reduced the latency to success across trials. Lions also demonstrated cognitive abilities associated with memory and solved the task after up to a 7-month testing interval. We also observed limited evidence for social facilitation of the task solution. Four of five initially unsuccessful lions achieved success after being partnered with a successful lion. Overall, our results support the presence of cognition associated with novel problem-solving, learning, and memory in lions. To date, our study is only the second experimental investigation of cognition in lions and further supports expanding cognitive research to lions.

An atomic gravitational wave interferometric sensor in low earth orbit (AGIS-LEO)

NASA Astrophysics Data System (ADS)

Hogan, Jason M.; Johnson, David M. S.; Dickerson, Susannah; Kovachy, Tim; Sugarbaker, Alex; Chiow, Sheng-Wey; Graham, Peter W.; Kasevich, Mark A.; Saif, Babak; Rajendran, Surjeet; Bouyer, Philippe; Seery, Bernard D.; Feinberg, Lee; Keski-Kuha, Ritva

2011-07-01

We propose an atom interferometer gravitational wave detector in low Earth orbit (AGIS-LEO). Gravitational waves can be observed by comparing a pair of atom interferometers separated by a 30 km baseline. In the proposed configuration, one or three of these interferometer pairs are simultaneously operated through the use of two or three satellites in formation flight. The three satellite configuration allows for the increased suppression of multiple noise sources and for the detection of stochastic gravitational wave signals. The mission will offer a strain sensitivity of {<10^{-18}/sqrt{Hz}} in the 50mHz-10Hz frequency range, providing access to a rich scientific region with substantial discovery potential. This band is not currently addressed with the LIGO, VIRGO, or LISA instruments. We analyze systematic backgrounds that are relevant to the mission and discuss how they can be mitigated at the required levels. Some of these effects do not appear to have been considered previously in the context of atom interferometry, and we therefore expect that our analysis will be broadly relevant to atom interferometric precision measurements. Finally, we present a brief conceptual overview of shorter-baseline ({lesssim100 m}) atom interferometer configurations that could be deployed as proof-of-principle instruments on the International Space Station (AGIS-ISS) or an independent satellite.

Carbon and nitrogen accumulation and fluxes on Landscape Evolution Observatory (LEO) slopes

NASA Astrophysics Data System (ADS)

Dontsova, K.; Volk, M.; Webb, C.; Hunt, E.; Tfaily, M. M.; Van Haren, J. L. M.; Sengupta, A.; Chorover, J.; Troch, P.; Ruiz, J.

2017-12-01

Carbon accumulation on the landscapes in organic and inorganic forms is an important sink of CO2 from the atmosphere. Formation and preservation of organic compounds is accompanied by N fixation from the atmosphere and cycling in the soil. Model slopes of Landscape Evolution Observatory present unique opportunity to examine carbon and nitrogen buildup on the landscapes during soil formation processes, such as weathering of primary minerals and microbial activity, due to low original levels of C and N, tight control over environmental conditions, and high spatial and temporal density of measurements. This presents results of inorganic and organic C and N measurements in the cores collected in LEO slopes after several years of exposure to the rainfall, as well as soil solution measurements collected through 496 samplers on each of three model slopes and in seepage. We observed significant spatially distributed accumulation of both C (organic and inorganic) and N in soil profiles. We also observed differences in the composition of organic compounds in the solid and solution phases depending on location on the slope indicating formation of heterogeneity as soils develop. This works indicates potential of physical models to help understand accumulation and fluxes of C and N on natural landscapes.

Aktiv De-Orbiting Onboard System from Leo of Upper Stages of Launchers

NASA Astrophysics Data System (ADS)

Trushlyakov, V.; Shalay, V.; Shatrov, J.; Jakovlev, M.; Kostantino, A.

2009-03-01

The active de-orbiting onboard system (VDOS) of upper separable parts (USP) stage of launchers from LEO into orbits of utilization with term of existence orbital lifetimes till 25 years is offered. ADOS it is based on use of power resources of not produced rests of liquid fuel onboard USP launchers with liquid propulsion module (LPM). Following systems enter in structure VDOS: the gas jet propulsion system consisting of a system of gasification, chambers of gas engines (GE), a control system. For gasification of the rests of liquid fuel the heat-carrier received in the autonomous gas generator is used. The gasification propellant components from each tank with temperature and the pressure determined by strength of the corresponding tank, move in chambers of the GE established on a top of a fuel compartment. After separation of a payload execute twist USP for preservation of its position in the space by activity of the GE. Ways of increase of a system effectiveness of gasification are offered by superposition on the entered heat-carrier of ultrasonic oscillations, and also introduction in gaseous fuel nanopowder of aluminum. The volume of adaptations of construction USP, connected with introduction VDOS does not exceed 5 % from weight of a dry construction.

Nonlinear Analysis of the Space Shuttle Superlightweight LO2 Tank. Part 2; Behavior Under 3g End-of-Flight Loads

NASA Technical Reports Server (NTRS)

Nemeth, Michael P.; Young, Richard D.; Collins, Timothy J.; Starnes, James H.,Jr.

1998-01-01

Results of linear bifurcation and nonlinear analyses of the Space Shuttle super lightweight (SLWT) external liquid-oxygen (LO2) tank are presented for an important end-of-flight loading condition. These results illustrate an important type of response mode for thin-walled shells, that are subjected to combined mechanical and thermal loads, that may be encountered in the design of other liquid-fuel launch vehicles. Linear bifurcation analyses are presented that predict several nearly equal eigenvalues that correspond to local buckling modes in the aft dome of the LO2 tank. In contrast, the nonlinear response phenomenon is shown to consist of a short-wavelength bending deformation in the aft elliptical dome of the LO2 tank that grows in amplitude in a stable manner with increasing load. Imperfection sensitivity analyses are presented that show that the presence of several nearly equal eigenvalues does not lead to a premature general instability mode for the aft dome. For the linear bifurcation and nonlinear analyses, the results show that accurate predictions of the response of the shell generally require a large-scale, high fidelity finite-element model. Results are also presented that show that the SLWT LO2 tank can support loads in excess of approximately 1.9 times the values of the operational loads considered.

Short and long term efficiencies of debris risk reduction measures: Application to a European LEO mission

NASA Astrophysics Data System (ADS)

Lang, T.; Kervarc, R.; Bertrand, S.; Carle, P.; Donath, T.; Destefanis, R.; Grassi, L.; Tiboldo, F.; Schäfer, F.; Kempf, S.; Gelhaus, J.

2015-01-01

Recent numerical studies indicate that the low Earth orbit (LEO) debris environment has reached a point such that even if no further space launches were conducted, the Earth satellite population would remain relatively constant for only the next 50 years or so. Beyond that, the debris population would begin to increase noticeably, due to the production of collisional debris (Liou and Johnson, 2008). Measures to be enforced play thus a major role to preserve an acceptable space mission risk and ensure sustainable space activities. The identification of such measures and the quantification of their efficiency over time for LEO missions is of prime concern in the decision-making process, as it has been investigated for the last few decades by the Inter-Agency Space Debris Coordination Committee (IADC). This paper addresses the final results of a generic methodology and the characteristics of a tool developed to assess the efficiency of the risk reduction measures identified for the Sentinel-1 (S1) mission. This work is performed as part of the 34-month P2-ROTECT project (Prediction, Protection & Reduction of OrbiTal Exposure to Collision Threats), funded by the European Union within the Seventh Framework Programme. Three ways of risk reduction have been investigated, both in short and long-term, namely: better satellite protection, better conjunction prediction, and cleaner environment. According to our assumptions, the S1 mission vulnerability evaluations in the long term (from 2093 to 2100) show that full compliance to the mitigation measures leads to a situation twice safer than that induced by an active debris removal of 5 objects per year in a MASTER2009 Business-As-Usual context. Because these measures have visible risk reduction effects in the long term, complementary measures with short response time are also studied. In the short term (from 2013 to 2020), a better prediction of the conjunctions is more efficient than protecting the satellite S1 itself. By

Design, Calibration, and Expected On-Orbit Performance of the GOES-R MPS-LO Suprathermal Plasma Analyzer Instrument

NASA Astrophysics Data System (ADS)

Golightly, M. J.; McGarity, J. O.; Dichter, B. K.; Galica, G. E.

2015-12-01

The next generation U.S. geosynchronous weather satellite—GOES series R-U—will include for the first time a suprathermal plasma analyzer. The Magnetospheric Particle Sensor-Low (MPS-LO), an electrostatic analyzer utilizing triquadrispheric geometry (270° turn)deflection electrodes, will measure the flux of electrons and ions with energies between 30 eV - 30 keV in fifteen logarithmically-spaced differential energy channels and arrival direction in twelve angular bins. MPS-LO consists of two sensor heads mounted in a common electronics box. Each sensor head contains a set of deflection electrodes, microchannel plates, and segmented detector anodes. The common electronics box provides the power and I/O interface with a data processing unit, voltage supplies for all of the instrument's electronics, high voltage for the deflection electrodes, in-flight calibration pulsers, and the digital electronics to process signals from sensor heads' detector anodes. Great care was taken in the manufacture and mounting of the triquadrisphere deflection electrodes; each electrode was machined from a single piece of aluminum and specific electrode combinations were mounted with precision machined spacers and matched drilling. The precise fabrication and assembly resulted in near perfect spherical electric fields between the electrodes. The triquadrispheric electrode shape also prevents photons from reaching the detection elements-as a result, MPS-LO is solar blind. The combined field-of-view for the two sensor heads is 180° x 5°, with the larger angle in a plane perpendicular to the spacecraft's orbit and its central axis oriented anti-Earthward. An incident particle's arrival direction is determined in one of twelve 15° x 5° angular zones. A set of shielded anodes is used to measure the background caused by penetrating charged particles that reach the MCPs; this background data is used to correct the MPS-LO data. The instrument's energy resolution ΔE/E is 5.8%.

Structural Validity of the Professional Development Profile of the LoTi Digital-Age Survey

ERIC Educational Resources Information Center

Mehta, Vandhana; Hull, Darrell M.

2013-01-01

The present study was used to examine the structural construct validity of the Professional Development Profile of the LoTi Digital-Age Survey, a measure of teacher instructional practices with technology in the classroom. Teacher responses ("N" = 2,840) from across the United States were used to assess factor structure of the instrument…

Combustion characteristics of the LO2/GCH4 fuel-rich preburners for staged combustion cycle rocket engines

NASA Astrophysics Data System (ADS)

Ono, Fumiei; Tamura, Hiroshi; Sakamoto, Hiroshi; Sasaki, Masaki

1991-09-01

The combustion characteristics of Liquid Oxygen (LO2)/Gaseous Methane (GCH4) fuel rich preburners were experimentally studied using subscale hardware. Three types of preburners with coaxial type propellant injection elements were designed and fabricated, and were used for hot fire testing. LO2 was used as oxidizer, and GCH4 at room temperature was used as fuel. The tests were conducted at chamber pressures ranging from 6.7 to 11.9 M Pa, and oxidizer to fuel ratios ranged from 0.16 to 0.42. The test results, which include combustion gas temperature T(sub c), characteristic velocity C(sup *) and soot adhesion data, are presented. The T(sub c) efficiency and the C(sup *) efficiency were found to be a function of oxidizer to fuel ratio and chamber pressure. These efficiencies are correlated by an empirical correlation parameter which accounts for the effects of oxidizer to fuel ratio and chamber pressure. The exhaust plumes were colorless and transparent under all tests conditions. There was some soot adhesion to the chamber wall, but no soot adhesion was observed on the main injector simulator orifices. Higher temperature igniter gas was required to ignite the main propellants of the preburner compared with that of the LO2/Gaseous Hydrogen (GH2) propellants combination.

Realistic and affordable lo-fidelity model for learning bronchoscopic transbronchial needle aspiration.

PubMed

Goldberg, Robert; Colt, Henri G; Davoudi, Mohsen; Cherrison, Larry

2009-09-01

Transbronchial needle aspiration (TBNA) is used to sample mediastinal abnormalities and lymph node stations for diagnostic purposes and lung cancer staging. The procedure is underused, operator dependent, and reputed to have a steep learning curve. Other difficulties arise from a bronchoscopist's failure to insert the needle satisfactorily into the target node. The purpose of this study was to evaluate the realism and helpfulness of a lo-fidelity, easily constructed hybrid model used for learning and practicing TBNA. The model is constructed by attaching a porcine tracheobronchial tree to a Laerdal Airway Model mounted on polyvinyl chloride (PVC) piping. Twelve individuals with various levels of bronchoscopy training and experience were given a 15-min introductory PowerPoint presentation on TBNA strategy and planning, execution, and response to complications. Participants then practiced TBNA alone and with guidance, aided by an assistant, as many times as individually necessary to feel comfortable with the procedure. A five-point Likert scale 8-item questionnaire was then completed. Participants were unanimously positive about their experience (mean scores 4.25-4.91). The model was realistic, provided increased comfort with TBNA techniques, and allowed practice of communication skills. This realistic, affordable, and easily constructed hybrid lo-fidelity airway model allows beginner and experienced bronchoscopists opportunities to learn and practice basic TBNA techniques and team communication skills without placing patients at risk.

Leo stent for endovascular treatment of intracranial aneurysms: very long-term results in 50 patients with 52 aneurysms and literature review.

PubMed

Lubicz, Boris; Kadou, Alexandre; Morais, Ricardo; Mine, Benjamin

2017-03-01

The Leo stent was the first retrievable stent for endovascular treatment of intracranial aneurysms (IAs). We report our experience with this device with emphasis on very long-term follow-up. This study was approved by authors' ethical committee. A retrospective review of our prospectively maintained database identified all patients treated for a saccular IA with this stent in our institution. Technical issues and immediate and long-term outcomes (at least 12 months) were evaluated. Between 2004 and 2015, 50 patients with 52 IAs were identified. In two patients, the stent could not safely be placed (failure rate = 3.8%). Among 48 treated patients with 50 IAs, there were 44 women and 4 men (mean age, 53 years). Mean aneurysm diameter was 7.2 mm. All IAs but six were wide-necked. There was no immediate morbidity or mortality. Anatomical results included 76% complete occlusions, 22% neck remnants, and 2% incomplete occlusions. Mean follow-up was 50.2 months (range, 12-139 months). Two patients had delayed TIAs but long-term morbidity rate remained = 0%. At follow-up, occlusion was stable in 68% IAs, showed thrombosis in 12%, and recanalization in 20% IAs. Complementary treatment was required in 8% IAs. Final results showed 70% complete occlusions, 24% neck remnants, and 6% incomplete occlusions. Asymptomatic stent occlusion and significant stenosis occurred in one and two cases, respectively. The Leo stent is safe and effective for treatment of wide-necked saccular IAs. Very long-term results show high rates of adequate and stable occlusion. Moreover, the stent is well tolerated.

Space Shuttle - Bringing cryohydrogen technology down to earth. [details of LH2 and LO2 technology and External Tank design

NASA Technical Reports Server (NTRS)

Odom, J. B.

1978-01-01

The External Tank must provide a safe storage container for both LH2 and LO2, a means of maintaining propellant quality in order to meet the engine pump net positive suction pressure requirements, and a structural strong-back for the Space Shuttle system, all at the minimum recurring cost and weight, while maintaining quality and reliability. The present paper summarizes External Tank design features and discusses the advantages of using LH2 and LO2 for the Space Shuttle system.

100-LBF LO2/LCH4 - Reaction Control Engine Technology Development for Future Space Vehicles

NASA Technical Reports Server (NTRS)

Robinson, Philip J.; Veith, Eric M.; Hurlbert, Eric A.; Jimenez, Rafael; Smith, Timothy D.

2008-01-01

The National Aeronautics and Space Administration (NASA) has identified liquid oxygen (LO2)/liquid methane (LCH4) propulsion systems as promising options for some future space vehicles. NASA issued a contract to Aerojet to develop a 100-lbf (445 N) LO2/LCH4 Reaction Control Engine (RCE) aimed at reducing the risk of utilizing a cryogenic reaction control system (RCS) on a space vehicle. Aerojet utilized innovative design solutions to develop an RCE that can ignite reliably over a broad range of inlet temperatures, perform short minimum impulse bits (MIB) at small electrical pulse widths (EPW), and produce excellent specific impulse (Isp) across a range of engine mixture ratios (MR). These design innovations also provide a start transient with a benign MR, ensuring good thrust chamber compatibility and long life. In addition, this RCE can successfully operate at MRs associated with main engines, enabling the RCE to provide emergency backup propulsion to minimize vehicle propellant load and overall system mass.

Mapping the Space Radiation Environment in LEO Orbit by the SATRAM Timepix Payload On Board the Proba-V Satellite

NASA Astrophysics Data System (ADS)

Granja, Carlos; Polansky, Stepan; Sospisil, Stanislav; Owens, Alan; Mellab, Karim

2016-08-01

The compact spacecraft payload SATRAM is operating in LEO orbit since 2013 on board the Proba-V satellite from ESA and provides high-resolution wide-range radiation monitoring of the satellite environment. Equipped with the pixel detector Timepix, the technology demonstration payload determines the composition (particle types) and spectral characterization (stopping power) of the mixed radiation field with quantum imaging sensitivity, charged particle tracking, energy loss and directionality capability. With a polar orbit (sun synchronous, 98° inclination) and altitude of 820 km the space radiation field is continuously sampled over the entire planet every few days. Results are given in the form of spatial- and time- correlated maps of dose rate and particle flux. Comparison is made between quiescent and geomagnetic storm activity periods.

Three dimensional HiLo-based structured illumination for a digital scanned laser sheet microscopy (DSLM) in thick tissue imaging

PubMed Central

Bhattacharya, Dipanjan; Singh, Vijay Raj; Zhi, Chen; So, Peter T. C.; Matsudaira, Paul; Barbastathis, George

2012-01-01

Laser sheet based microscopy has become widely accepted as an effective active illumination method for real time three-dimensional (3D) imaging of biological tissue samples. The light sheet geometry, where the camera is oriented perpendicular to the sheet itself, provides an effective method of eliminating some of the scattered light and minimizing the sample exposure to radiation. However, residual background noise still remains, limiting the contrast and visibility of potentially interesting features in the samples. In this article, we investigate additional structuring of the illumination for improved background rejection, and propose a new technique, “3D HiLo” where we combine two HiLo images processed from orthogonal directions to improve the condition of the 3D reconstruction. We present a comparative study of conventional structured illumination based demodulation methods, namely 3Phase and HiLo with a newly implemented 3D HiLo approach and demonstrate that the latter yields superior signal-to-background ratio in both lateral and axial dimensions, while simultaneously suppressing image processing artifacts. PMID:23262684

Circulating precursor CCR7(lo)PD-1(hi) CXCR5⁺ CD4⁺ T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure.

PubMed

He, Jing; Tsai, Louis M; Leong, Yew Ann; Hu, Xin; Ma, Cindy S; Chevalier, Nina; Sun, Xiaolin; Vandenberg, Kirsten; Rockman, Steve; Ding, Yan; Zhu, Lei; Wei, Wei; Wang, Changqi; Karnowski, Alexander; Belz, Gabrielle T; Ghali, Joanna R; Cook, Matthew C; Riminton, D Sean; Veillette, André; Schwartzberg, Pamela L; Mackay, Fabienne; Brink, Robert; Tangye, Stuart G; Vinuesa, Carola G; Mackay, Charles R; Li, Zhanguo; Yu, Di

2013-10-17

Follicular B helper T (Tfh) cells support high affinity and long-term antibody responses. Here we found that within circulating CXCR5⁺ CD4⁺ T cells in humans and mice, the CCR7(lo)PD-1(hi) subset has a partial Tfh effector phenotype, whereas CCR7(hi)PD-1(lo) cells have a resting phenotype. The circulating CCR7(lo)PD-1(hi) subset was indicative of active Tfh differentiation in lymphoid organs and correlated with clinical indices in autoimmune diseases. Thus the CCR7(lo)PD-1(hi) subset provides a biomarker to monitor protective antibody responses during infection or vaccination and pathogenic antibody responses in autoimmune diseases. Differentiation of both CCR7(hi)PD-1(lo) and CCR7(lo)PD-1(hi) subsets required ICOS and BCL6, but not SAP, suggesting that circulating CXCR5⁺ helper T cells are primarily generated before germinal centers. Upon antigen reencounter, CCR7(lo)PD-1(hi) CXCR5⁺ precursors rapidly differentiate into mature Tfh cells to promote antibody responses. Therefore, circulating CCR7(lo)PD-1(hi) CXCR5⁺ CD4⁺ T cells are generated during active Tfh differentiation and represent a new mechanism of immunological early memory. Copyright © 2013 Elsevier Inc. All rights reserved.

Toxicity testing of four silver nanoparticle-coated dental castings in 3-D LO2 cell cultures.

PubMed

Zhao, Yi-Ying; Chu, Qiang; Shi, Xu-Er; Zheng, Xiao-Dong; Shen, Xiao-Ting; Zhang, Yan-Zhen

To address the controversial issue of the toxicity of dental alloys and silver nanoparticles in medical applications, an in vivo-like LO2 3-D model was constructed within polyvinylidene fluoride hollow fiber materials to mimic the microenvironment of liver tissue. The use of microscopy methods and the measurement of liver-specific functions optimized the model for best cell performances and also proved the superiority of the 3-D LO2 model when compared with the traditional monolayer model. Toxicity tests were conducted using the newly constructed model, finding that four dental castings coated with silver nanoparticles were toxic to human hepatocytes after cell viability assays. In general, the toxicity of both the castings and the coated silver nanoparticles aggravated as time increased, yet the nanoparticles attenuated the general toxicity by preventing metal ion release, especially at high concentrations.

[Effects of HiLo for two weeks on erythrocyte immune adhesion and leukocyte count of swimmers].

PubMed

Zhao, Yong-Cai; Gao, Bing-Hong; Wu, Ge-Lin; Zhang, Jiu-Li

2012-07-01

To investigate the effects of living high-training low (HiLo) on innate immunity in blood of elite swimmers. Six female swimmers undertook HiLo for two weeks, erythrocyte adhesion function and counts of leukocyte were tested in different time of training period. Red blood cell C3b receptor ring rate (RBC-C3bRR) decreased and red blood cell immune complex matter ring rate (RBC-ICR) increased significantly (P < 0.05), the two markers returned to base line 1 week after training. Counts of leukocyte and granulocyte decreased significantly (P < 0.05), and they recovered 1 week after training; Counts of lymphocyte and monocyte decreased without significance during training and did not recovered after training. Immunity of erythrocyte and granulocyte decreased quickly, but lymphocyte and monocyte recovered slowly, swimmers were adaptive to the training.

Seamount Hydrothermal Systems as Analogies for Ocean Worlds: Reaction Paths Throughout the Lo'ihi Seamount (Hawaii Archipelago)

NASA Astrophysics Data System (ADS)

Milesi, V.; Shock, E.

2018-05-01

Thermodynamic modeling is performed to investigate the possible reaction paths of sea water throughout the Lo'ihi seamount and the associated geochemical supplies of energy that can support autotrophic microbial communities.

Lunar Occultations, Setting the Stage for VLTI: The Case Study of CW-Leo (aka IRC+10216)

NASA Astrophysics Data System (ADS)

Käufl, Hans Ulrich; Stecklum, Bringfried; Richter, Steffen; Richichi, Andrea

Lunar occultation allows for a sneak preview of what the VLTI will observe, both with comparable angular resolution and sensitivity. In the thermal infrared ( λ ≈ 10μ m, angular resolution ≤ 0.03^' ') the technique has been pioneered with TIMMI on La Silla. Using this technique several dust shells around Asymptotic Giant Branch stars have been resolved. For the Carbon star CW-Leo (IRC+10 216) high S/N scans will allow for `11/2-dimensional' imaging of the source. At the present state of data reduction the light curves already provide for a very convincing proof of theories on the milli-arcsec scale. In combination with VLTI the technique allows for checks of the visibility calibration and related issues. Moreover, in the (u,v)-plane both techniques are extremely complementary, so that a merging of the data sets appear highly desirable. At La Silla and Paranal ESO a suite of instruments which can be (ab)used for this project is under construction.

Characterization of a bioflocculant produced by a consortium of Halomonas sp. Okoh and Micrococcus sp. Leo.

PubMed

Okaiyeto, Kunle; Nwodo, Uchechukwu U; Mabinya, Leonard V; Okoh, Anthony I

2013-10-16

The physicochemical and flocculating properties of a bioflocculant produced by a bacterial consortium composed of Halomonas sp. Okoh and Micrococcus sp. Leo were investigated. The purified bioflocculant was cation and pH dependent, and optimally flocculated kaolin clay suspension at a dosage of 0.1 mg/mL. The flocculating activity of the bioflocculant was stimulated in the presence of Ca2+, Mn2+, Al3+ and had a wide pH range of 2-10, with the highest flocculating activity of 86% at pH 8. The bioflocculant was thermostable and retained more than 70% of its flocculating activity after being heated at 80 °C for 30 min. Thermogravimetric analyses revealed a partial thermal decomposition of the biofloculant at 400 °C. The infrared spectrum showed the presence of hydroxyl, carboxyl and amino moieties as functional groups. The bioflocculant produced by the bacterial consortium appears to hold promising alternative to inorganic and synthetic organic flocculants that are widely used in wastewater treatment.

Characterization of a Bioflocculant Produced by a Consortium of Halomonas sp. Okoh and Micrococcus sp. Leo

PubMed Central

Okaiyeto, Kunle; Nwodo, Uchechukwu U.; Mabinya, Leonard V.; Okoh, Anthony I.

2013-01-01

The physicochemical and flocculating properties of a bioflocculant produced by a bacterial consortium composed of Halomonas sp. Okoh and Micrococcus sp. Leo were investigated. The purified bioflocculant was cation and pH dependent, and optimally flocculated kaolin clay suspension at a dosage of 0.1 mg/mL. The flocculating activity of the bioflocculant was stimulated in the presence of Ca2+, Mn2+, Al3+ and had a wide pH range of 2–10, with the highest flocculating activity of 86% at pH 8. The bioflocculant was thermostable and retained more than 70% of its flocculating activity after being heated at 80 °C for 30 min. Thermogravimetric analyses revealed a partial thermal decomposition of the biofloculant at 400 °C. The infrared spectrum showed the presence of hydroxyl, carboxyl and amino moieties as functional groups. The bioflocculant produced by the bacterial consortium appears to hold promising alternative to inorganic and synthetic organic flocculants that are widely used in wastewater treatment. PMID:24135818

Normas finales de desempeño para fuentes nuevas y revisión de tecnología y riesgos del sector de refinería de petróleo-resumen de cambios

EPA Pesticide Factsheets

La Agencia de Protección Ambiental (EPA, por sus siglas en inglés) emitió un reglamento final que mejorará significativamente la calidad del aire en los vecindarios cercanos a las refinerías de petróleo mediante un control más exhaustivo de las emisiones a

Smart City Pilot Projects Using LoRa and IEEE802.15.4 Technologies

PubMed Central

Buratti, Chiara; Zabini, Flavio; De Castro, Cristina; Verdone, Roberto; Andrisano, Oreste

2018-01-01

Information and Communication Technologies (ICTs), through wireless communications and the Internet of Things (IoT) paradigm, are the enabling keys for transforming traditional cities into smart cities, since they provide the core infrastructure behind public utilities and services. However, to be effective, IoT-based services could require different technologies and network topologies, even when addressing the same urban scenario. In this paper, we highlight this aspect and present two smart city testbeds developed in Italy. The first one concerns a smart infrastructure for public lighting and relies on a heterogeneous network using the IEEE 802.15.4 short-range communication technology, whereas the second one addresses smart-building applications and is based on the LoRa low-rate, long-range communication technology. The smart lighting scenario is discussed providing the technical details and the economic benefits of a large-scale (around 3000 light poles) flexible and modular implementation of a public lighting infrastructure, while the smart-building testbed is investigated, through measurement campaigns and simulations, assessing the coverage and the performance of the LoRa technology in a real urban scenario. Results show that a proper parameter setting is needed to cover large urban areas while maintaining the airtime sufficiently low to keep packet losses at satisfactory levels. PMID:29642391

Smart City Pilot Projects Using LoRa and IEEE802.15.4 Technologies.

PubMed

Pasolini, Gianni; Buratti, Chiara; Feltrin, Luca; Zabini, Flavio; De Castro, Cristina; Verdone, Roberto; Andrisano, Oreste

2018-04-06

Information and Communication Technologies (ICTs), through wireless communications and the Internet of Things (IoT) paradigm, are the enabling keys for transforming traditional cities into smart cities, since they provide the core infrastructure behind public utilities and services. However, to be effective, IoT-based services could require different technologies and network topologies, even when addressing the same urban scenario. In this paper, we highlight this aspect and present two smart city testbeds developed in Italy. The first one concerns a smart infrastructure for public lighting and relies on a heterogeneous network using the IEEE 802.15.4 short-range communication technology, whereas the second one addresses smart-building applications and is based on the LoRa low-rate, long-range communication technology. The smart lighting scenario is discussed providing the technical details and the economic benefits of a large-scale (around 3000 light poles) flexible and modular implementation of a public lighting infrastructure, while the smart-building testbed is investigated, through measurement campaigns and simulations, assessing the coverage and the performance of the LoRa technology in a real urban scenario. Results show that a proper parameter setting is needed to cover large urban areas while maintaining the airtime sufficiently low to keep packet losses at satisfactory levels.

LEO Download Capacity Analysis for a Network of Adaptive Array Ground Stations

NASA Technical Reports Server (NTRS)

Ingram, Mary Ann; Barott, William C.; Popovic, Zoya; Rondineau, Sebastien; Langley, John; Romanofsky, Robert; Lee, Richard Q.; Miranda, Felix; Steffes, Paul; Mandl, Dan

2005-01-01

To lower costs and reduce latency, a network of adaptive array ground stations, distributed across the United States, is considered for the downlink of a polar-orbiting low earth orbiting (LEO) satellite. Assuming the X-band 105 Mbps transmitter of NASA s Earth Observing 1 (EO-1) satellite with a simple line-of-sight propagation model, the average daily download capacity in bits for a network of adaptive array ground stations is compared to that of a single 11 m dish in Poker Flats, Alaska. Each adaptive array ground station is assumed to have multiple steerable antennas, either mechanically steered dishes or phased arrays that are mechanically steered in azimuth and electronically steered in elevation. Phased array technologies that are being developed for this application are the space-fed lens (SFL) and the reflectarray. Optimization of the different boresight directions of the phased arrays within a ground station is shown to significantly increase capacity; for example, this optimization quadruples the capacity for a ground station with eight SFLs. Several networks comprising only two to three ground stations are shown to meet or exceed the capacity of the big dish, Cutting the data rate by half, which saves modem costs and increases the coverage area of each ground station, is shown to increase the average daily capacity of the network for some configurations.

pH-sensitive nanomicelles for controlled and efficient drug delivery to human colorectal carcinoma LoVo cells.

PubMed

Feng, Shi-Ting; Li, Jingguo; Luo, Yanji; Yin, Tinghui; Cai, Huasong; Wang, Yong; Dong, Zhi; Shuai, Xintao; Li, Zi-Ping

2014-01-01

The triblock copolymers PEG-P(Asp-DIP)-P(Lys-Ca) (PEALCa) of polyethylene glycol (PEG), poly(N-(N',N'-diisopropylaminoethyl) aspartamide) (P(Asp-DIP)), and poly (lysine-cholic acid) (P(Lys-Ca)) were synthesized as a pH-sensitive drug delivery system. In neutral aqueous environment such as physiological environment, PEALCa can self-assemble into stable vesicles with a size around 50-60 nm, avoid uptake by the reticuloendothelial system (RES), and encase the drug in the core. However, the PEALCa micelles disassemble and release drug rapidly in acidic environment that resembles lysosomal compartments. The anticancer drug Paclitaxel (PTX) and hydrophilic superparamagnetic iron oxide (SPIO) were encapsulated inside the core of the PEALCa micelles and used for potential cancer therapy. Drug release study revealed that PTX in the micelles was released faster at pH 5.0 than at pH 7.4. Cell culture studies showed that the PTX-SPIO-PEALCa micelle was effectively internalized by human colon carcinoma cell line (LoVo cells), and PTX could be embedded inside lysosomal compartments. Moreover, the human colorectal carcinoma (CRC) LoVo cells delivery effect was verified in vivo by magnetic resonance imaging (MRI) and histology analysis. Consequently effective suppression of CRC LoVo cell growth was evaluated. These results indicated that the PTX-SPION-loaded pH-sensitive micelles were a promising MRI-visible drug release system for colorectal cancer therapy.

ALFALFA and WSRT Imaging of Extended H I Features in the Leo Cloud of Galaxies

NASA Astrophysics Data System (ADS)

Leisman, Lukas; Haynes, Martha P.; Giovanelli, Riccardo; Józsa, Gyula; Adams, Elizabeth A. K.; Hess, Kelley M.

2016-12-01

We present Arecibo Legacy Fast ALFA (ALFALFA) H I observations of a well-studied region of the Leo Cloud, which includes the NGC 3227 group and the NGC 3190 group. We detect optically dark H I tails and plumes with extents potentially exceeding 600 kpc, well beyond the field of view of previous observations. These H I features contain ˜40 per cent of the total H I mass in the NGC 3227 group and ˜10 per cent of the NGC 3190 group. We also present Westerbork Synthesis Radio Telescope (WSRT) maps which show the complex morphology of the extended emission in the NGC 3227 group. We comment on previously proposed models of the interactions in these groups and the implications for the scale of group processing through interactions. Motivated by the extent of the H I plumes, we place the H I observations in the context of the larger loose group, demonstrating the need for future sensitive, wide field H I surveys to understand the role of group processing in galaxy evolution.

Model-Based GN and C Simulation and Flight Software Development for Orion Missions beyond LEO

NASA Technical Reports Server (NTRS)

Odegard, Ryan; Milenkovic, Zoran; Henry, Joel; Buttacoli, Michael

2014-01-01

For Orion missions beyond low Earth orbit (LEO), the Guidance, Navigation, and Control (GN&C) system is being developed using a model-based approach for simulation and flight software. Lessons learned from the development of GN&C algorithms and flight software for the Orion Exploration Flight Test One (EFT-1) vehicle have been applied to the development of further capabilities for Orion GN&C beyond EFT-1. Continuing the use of a Model-Based Development (MBD) approach with the Matlab®/Simulink® tool suite, the process for GN&C development and analysis has been largely improved. Furthermore, a model-based simulation environment in Simulink, rather than an external C-based simulation, greatly eases the process for development of flight algorithms. The benefits seen by employing lessons learned from EFT-1 are described, as well as the approach for implementing additional MBD techniques. Also detailed are the key enablers for improvements to the MBD process, including enhanced configuration management techniques for model-based software systems, automated code and artifact generation, and automated testing and integration.

Spacecraft-plasma interaction codes: NASCAP/GEO, NASCAP/LEO, POLAR, DynaPAC, and EPSAT

NASA Technical Reports Server (NTRS)

Mandell, M. J.; Jongeward, G. A.; Cooke, D. L.

1992-01-01

Development of a computer code to simulate interactions between the surfaces of a geometrically complex spacecraft and the space plasma environment involves: (1) defining the relevant physical phenomena and formulating them in appropriate levels of approximation; (2) defining a representation for the 3-D space external to the spacecraft and a means for defining the spacecraft surface geometry and embedding it in the surrounding space; (3) packaging the code so that it is easy and practical to use, interpret, and present the results; and (4) validating the code by continual comparison with theoretical models, ground test data, and spaceflight experiments. The physical content, geometrical capabilities, and application of five S-CUBED developed spacecraft plasma interaction codes are discussed. The NASA Charging Analyzer Program/geosynchronous earth orbit (NASCAP/GEO) is used to illustrate the role of electrostatic barrier formation in daylight spacecraft charging. NASCAP/low Earth orbit (LEO) applications to the CHARGE-2 and Space Power Experiment Aboard Rockets (SPEAR)-1 rocket payloads are shown. DynaPAC application to the SPEAR-2 rocket payloads is described. Environment Power System Analysis Tool (EPSAT) is illustrated by application to Tethered Satellite System 1 (TSS-1), SPEAR-3, and Sundance. A detailed description and application of the Potentials of Large Objects in the Auroral Region (POLAR) Code are presented.

L-Mapping Solar Energetic Particles from LEO to High Altitudes at High Latitudes

NASA Astrophysics Data System (ADS)

Young, S. L.; Wilson, G.

2017-12-01

The current solar energetic particle (SEP) hazard specification is focused on geosynchronous orbit with some capability at LEO, but there is no specification for the large region between these orbital regimes. The L-mapping technique, which attempts to fill this capability gap, assumes that there is a simple relationship between magnetic L-shells and SEP penetration boundaries that can be exploited. A previous study compared POES observations that had been mapped to the Van Allen Probes with local observations. It found that more than 90% of the mapped and local fluxes were within a factor of four of each other; this is thought to be sucient for operational purposes. One concern with the previous study was the limited number of SEP events that have occurred during the Van Allen Probes mission. The current study examines the L-mapping method's accuracy at higher latitudes. Observations from a satellite that was launched into a HEO orbit with a 63° inclination before the peak of solar cycle 24 are compared to L-mapped POES observations. The larger number of events provides better statistics and the 63° orbit inclination allows us to examine the difference between mapping from POES to the magnetic equator, as in the previous study, and mapping from POES to higher latitudes.

Support for the Symposium on the Application of Geophysics to Environmental and Engineering Problems, 2012-2014

DTIC Science & Technology

2014-07-02

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Preliminary design of 1 kW bipolar Ni-MH battery for LEO-satellite application

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cole, J.H.; Reisner, D.E.; Klein, M.G.

1996-12-31

Electro Energy, Inc. (EEI) is developing a bipolar nickel-metal hydride rechargeable battery based upon the use of stackable wafer cells. The key to viable bipolar operation has been this unique modular (unitized) approach. The patented unit wafer-cell construct exploits the chemical and thermal properties of a proprietary electrically conductive plastic film. Characteristic of bipolar batteries, current flows across the cell interfaces-perpendicular to the electrode plane. EEI has recently contracted with NASA Lewis Research Center (LeRC) to develop an optimized design 1 kW flightweight battery, for low-earth-orbit (LEO) satellite applications, over a 4-year period with a deliverable flightweight design package. Themore » contract includes an option for EEI to deliver up to three flight quality batteries in an 18-month follow-on program. NASA LeRC has promulgated that the program steps include the design, fabrication, and evaluation of four evolutionary stages of the final battery design which have been designated Preliminary, Improved, Optimized, and Flightweight Design. Initial results from the Preliminary Stage are presented including a 1 kW battery design, thermal design, parameter study, and component development in subscale bipolar batteries.« less

Building an LO source at 1036 GHz for a receiver

NASA Technical Reports Server (NTRS)

Erickson, Neal R.

1995-01-01

The goal of the UMass work on this grant was to build an LO source at 1036 GHz for a receiver which was to be built at JPL. The 1 THz source will consist of a high power Gunn oscillator at 86 GHz followed by a cascaded pair of planar diode doublers and finally a whisker contacted tripler. All multipliers will use single mode waveguide mounts. This use of single mode waveguide even for the final mount is a departure from the original plan, and reflects the progress that has been made in fabricating small structures. The advantages to the use of waveguide over a quasi-optical approach are that the complete system is much more compact, and much easier to use.

Investigation of lightweight designs and materials for LO2 and LH2 propellant tanks for space vehicles, phase 2 and phase 3

NASA Technical Reports Server (NTRS)

1976-01-01

Full size Tug LO2 and LH2 tank configurations were defined, based on selected tank geometries. These configurations were then locally modeled for computer stress analysis. A large subscale test tank, representing the selected Tug LO2 tank, was designed and analyzed. This tank was fabricated using procedures which represented production operations. An evaluation test program was outlined and a test procedure defined. The necessary test hardware was also fabricated.

Hydrogeology and analysis of ground-water withdrawal in the Mendenhall-D'Lo area, Simpson County, Mississippi

USGS Publications Warehouse

Strom, E.W.; Oakley, W.T.

1995-01-01

The cities of Mendenhall and D'Lo, located in Simpson County, rely on ground water for their public supply and industrial needs. Most of the ground water comes from an aquifer of Miocene age. A study began in 1991 to describe the hydrogeology, analyze effects of ground-water withdrawal by making a drawdown map, and estimate the effects increased ground-water withdrawal might have on water levels in the Miocene age aquifer in the Mendenhall-D'Lo area. The most significant withdrawals of ground water in the study area are from 10 wells screened in the lower sand of the Catahoula Formation of Miocene age. Analysis of the effect of withdrawals from the 10 wells was made using the Theis non- equilibrium equation and applying the principle of superposition. Analysis of 1994 conditions was based on the pumpage history and aquifer properties deter- mined for each well. The drawdown surface resulting from the analysis indicates three general cones of depression. One cone is in the northwestern D'Lo area, one in the south-central Mendenhall area, and one about 1-1/2 miles east of Mendenhall. Calculated drawdown ranges from 21 to 47 feet. Potential drawdown-surface maps were made for 10 years and 20 years beyond 1994 using a constant pumpage. The map made for 10 years beyond 1994 indicates an average total increase in drawdown of about 5.3 feet. The map made for 20 years beyond 1994 indicates an average total increase in drawdown of about 7.3 feet.

N3LO NN interaction adjusted to light nuclei in ab exitu approach

DOE PAGES

Shirokov, A. M.; Shin, I. J.; Kim, Y.; ...

2016-08-09

Here, we use phase-equivalent transformations to adjust off-shell properties of similarity renormalization group evolved chiral effective field theory NN interaction (Idaho N3LO) to fit selected binding energies and spectra of light nuclei in an ab exitu approach. Then, we test the transformed interaction on a set of additional observables in light nuclei to verify that it provides reasonable descriptions of these observables with an apparent reduced need for three- and many-nucleon interactions.

Baclofen has opposite effects on escalation of cocaine self-administration: increased intake in rats selectively bred for high (HiS) saccharin intake and decreased intake in those selected for low (LoS) saccharin intake

PubMed Central

Holtz, Nathan A.; Carroll, Marilyn E.

2011-01-01

Rats selectively bred for high saccharin intake (HiS) self-administer more cocaine, escalate their cocaine intake during long access, and reinstate cocaine seeking at higher levels than those bred for low saccharin intake (LoS). The present study was conducted to determine if baclofen, an agonist at the GABAb receptor, has differential effects on the escalation of i.v. cocaine intake and reinstatement of cocaine-seeking in HiS and LoS rats. HiS and LoS rats self-administered cocaine during a 2-h daily short-access (ShA) phase for 3 days and then long-access (LgA) sessions for 21 days followed by a second ShA phase. One group of HiS and LoS rats received i.p. injections of 2.5 mg/kg baclofen (HiS+B and LoS+B, respectively), and other groups of HiS and LoS rats received saline (HiS+Sal and LoS+Sal) before each daily session. In a second experiment, HiS and LoS rats self-administered i.v. cocaine during 2-h sessions for 14 days followed by a 21-day extinction period. Baclofen (2.5 mg/kg, i.p.) or saline was administered before saline- or cocaine-primed reinstatement sessions. The HiS+B group escalated their cocaine self-administration and had increased cocaine infusions in the post-LgA ShA phase. The LoS+B group self-administered less cocaine throughout the entire LgA period compared to the LoS+Sal or HiS groups. Baclofen attenuated reinstatement of cocaine seeking in both the HiS and LoS rats with no phenotype differences. Baclofen had opposite effects on cocaine intake in HiS and LoS rats during escalation; HiS increased and LoS decreased intake. These results suggest that treatment effects might vary with individual differences (HiS vs. LoS) and the phase of drug-motivated behavior that is modeled. PMID:21924281

100-Lb(f) LO2/LCH4 Reaction Control Engine Technology Development for Future Space Vehicles

NASA Technical Reports Server (NTRS)

Robinson, Philip J.; Veith, Eric M.; Hurlbert, Eric A.; Jimenez, Rafael; Smith, Timothy D.

2008-01-01

The National Aeronautics and Space Administration (NASA) has identified liquid oxygen (LO2)/liquid methane (LCH4) propulsion systems as promising options for some future space vehicles. NASA issued a contract to Aerojet to develop a 100-lbf (445 N) LO2/LCH4 Reaction Control Engine (RCE) aimed at reducing the risk of utilizing a cryogenic reaction control system (RCS) on a space vehicle. Aerojet utilized innovative design solutions to develop an RCE that can ignite reliably over a broad range of inlet temperatures, perform short minimum impulse bits (MIB) at small electrical pulse widths (EPW), and produce excellent specific impulse (Isp) across a range of engine mixture ratios (MR). These design innovations also provide a start transient with a benign MR, ensuring good thrust chamber compatibility and long life. In addition, this RCE can successfully operate at MRs associated with main engines, enabling the RCE to provide emergency backup propulsion to minimize vehicle propellant load and overall system mass.

A Study of the Relationship between Levels of Technology Implementation (LoTi) and Student Performance on Texas Assessment of Knowledge and Skills (TAKS) Scores

ERIC Educational Resources Information Center

Berkeley-Jones, Catherine Spotswood

2012-01-01

The purpose of this study was to examine teacher Levels of Technology Implementation (LoTi) self-ratings and student Texas Assessment of Knowledge and Skills (TAKS) scores. The study assessed the relationship between LoTi ratings and TAKS scores of 6th, 7th, and 8th grade students as reported in student records at Alamo Heights Independent School…

Reversible anaesthesia of free-ranging lions (Panthera leo) in Zimbabwe.

PubMed

Fahlman, A; Loveridge, A; Wenham, C; Foggin, C; Arnemo, J M; Nyman, G

2005-12-01

The combination of medetomidine-zolazepam-tiletamine with subsequent antagonism by atipamezole was evaluated for reversible anaesthesia of free-ranging lions (Panthera leo). Twenty-one anaesthetic events of 17 free-ranging lions (5 males and 12 females, body weight 105-211 kg) were studied in Zimbabwe. Medetomidine at 0.027-0.055 mg/kg (total dose 4-11 mg) and zolazepam-tiletamine at 0.38-1.32 mg/kg (total dose 50-275 mg) were administered i.m. by dart injection. The doses were gradually decreased to improve recovery. Respiratory and heart rates, rectal temperature and relative haemoglobin oxygen saturation (SpO2) were recorded every 15 min. Arterial blood samples were collected from 5 lions for analysis of blood gases and acid-base status. For anaesthetic reversal, atipamezole was administered i.m. at 2.5 or 5 times the medetomidine dose. Induction was smooth and all lions were anaesthetised with good muscle relaxation within 3.4-9.5 min after darting. The predictable working time was a minimum of 1 h and no additional drug doses were needed. Respiratory and heart rates and SpO2 were stable throughout anaesthesia, whereas rectal temperature changed significantly over time. Atipamezole at 2.5 times the medetomidine dose was sufficient for reversal and recoveries were smooth and calm in all lions independent of the atipamezole dose. First sign of recovery was observed 3-27 min after reversal. The animals were up walking 8-26 min after reversal when zolazepam-tiletamine doses < 1 mg/kg were used. In practice, a total dose of 6 mg medetomidine and 80 mg zolazepam-tiletamine and reversal with 15 mg atipamezole can be used for either sex of an adult or subadult lion. The drugs and doses used in this study provided a reliable, safe and reversible anaesthesia protocol for free-ranging lions.

Bayesian estimation of Karhunen–Loève expansions; A random subspace approach

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chowdhary, Kenny; Najm, Habib N.

One of the most widely-used statistical procedures for dimensionality reduction of high dimensional random fields is Principal Component Analysis (PCA), which is based on the Karhunen-Lo eve expansion (KLE) of a stochastic process with finite variance. The KLE is analogous to a Fourier series expansion for a random process, where the goal is to find an orthogonal transformation for the data such that the projection of the data onto this orthogonal subspace is optimal in the L 2 sense, i.e, which minimizes the mean square error. In practice, this orthogonal transformation is determined by performing an SVD (Singular Value Decomposition)more » on the sample covariance matrix or on the data matrix itself. Sampling error is typically ignored when quantifying the principal components, or, equivalently, basis functions of the KLE. Furthermore, it is exacerbated when the sample size is much smaller than the dimension of the random field. In this paper, we introduce a Bayesian KLE procedure, allowing one to obtain a probabilistic model on the principal components, which can account for inaccuracies due to limited sample size. The probabilistic model is built via Bayesian inference, from which the posterior becomes the matrix Bingham density over the space of orthonormal matrices. We use a modified Gibbs sampling procedure to sample on this space and then build a probabilistic Karhunen-Lo eve expansions over random subspaces to obtain a set of low-dimensional surrogates of the stochastic process. We illustrate this probabilistic procedure with a finite dimensional stochastic process inspired by Brownian motion.« less

Bayesian estimation of Karhunen–Loève expansions; A random subspace approach

DOE PAGES

Chowdhary, Kenny; Najm, Habib N.

2016-04-13

One of the most widely-used statistical procedures for dimensionality reduction of high dimensional random fields is Principal Component Analysis (PCA), which is based on the Karhunen-Lo eve expansion (KLE) of a stochastic process with finite variance. The KLE is analogous to a Fourier series expansion for a random process, where the goal is to find an orthogonal transformation for the data such that the projection of the data onto this orthogonal subspace is optimal in the L 2 sense, i.e, which minimizes the mean square error. In practice, this orthogonal transformation is determined by performing an SVD (Singular Value Decomposition)more » on the sample covariance matrix or on the data matrix itself. Sampling error is typically ignored when quantifying the principal components, or, equivalently, basis functions of the KLE. Furthermore, it is exacerbated when the sample size is much smaller than the dimension of the random field. In this paper, we introduce a Bayesian KLE procedure, allowing one to obtain a probabilistic model on the principal components, which can account for inaccuracies due to limited sample size. The probabilistic model is built via Bayesian inference, from which the posterior becomes the matrix Bingham density over the space of orthonormal matrices. We use a modified Gibbs sampling procedure to sample on this space and then build a probabilistic Karhunen-Lo eve expansions over random subspaces to obtain a set of low-dimensional surrogates of the stochastic process. We illustrate this probabilistic procedure with a finite dimensional stochastic process inspired by Brownian motion.« less

Analysing efficiency of IPv6 packet transmission over 6LoWPAN network

NASA Astrophysics Data System (ADS)

Kozłowski, Adam; Sosnowski, Janusz

2017-08-01

Practical proliferation of Internet of Things (IoT) concept depends upon communication efficiency in the related network. In the paper we outline basic features of wireless communication protocols used in IoT and concentrate on analysing communication overheads. In particular, we discuss the impact of IPv6 packet length on 6LoWPAN network operation with physical and MAC layer defined by IEEE 802.15.4 standard. The presented analysis methodology is useful in estimation of the total goodput (throughput at the application level) and energy consumptions within the whole traffic model which are the crucial features of IoT networks.

Estimated performance and future potential of solar dynamic and photovoltaic power systems for selected LEO and HEO missions

NASA Technical Reports Server (NTRS)

Bents, David J.; Lu, Cheng Y.

1989-01-01

Solar photovoltaic and thermal dynamic power systems for application to selected low-earth-orbit (LEO) and high-earth-orbit (HEO) missions are characterized in the regime 7 to 35 kWe. Input parameters to the characterization are varied to correspond to anticipated introduction of improved or new technologies. A comparative assessment is made of the two power system types for emerging technologies in cells and arrays, energy storage, optical surfaces, heat engines, thermal energy storage and thermal management. The assessment is made to common ground rules and assumptions. The four missions (Space Station, sun-synchronous, Van Allen belt, and GEO) are representative of the anticipated range of multikilowatt earth-orbit missions. The results give the expected performance, mass and drag of multikilowatt earth-orbiting solar power systems and show how the overall system figure of merit will improve as new component technologies are incorporated.

Unraveling the mysteries of the Leo Ring: An absorption line study of an unusual gas cloud

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rosenberg, J. L.; Haislmaier, Karl; Giroux, M. L.

2014-07-20

Since the discovery of the large (2 × 10{sup 9} M{sub ☉}) intergalactic cloud known as the Leo Ring in the 1980s, the origin of this object has been the center of a lively debate. Determining the origin of this object is still important as we develop a deeper understanding of the accretion and feedback processes that shape galaxy evolution. We present Hubble Space Telescope/Cosmic Origins Spectrograph observations of three sightlines near the ring, two of which penetrate the high column density neutral hydrogen gas visible in 21 cm observations of the object. These observations provide the first direct measurementmore » of the metallicity of the gas in the ring, an important clue to its origin. Our best estimate of the metallicity of the ring is ∼10% Z{sub ☉}, higher than expected for primordial gas but lower than expected from an interaction. We discuss possible modifications to the interaction and primordial gas scenarios that would be consistent with this metallicity measurement.« less

Bile Stress Response in Listeria monocytogenes LO28: Adaptation, Cross-Protection, and Identification of Genetic Loci Involved in Bile Resistance

PubMed Central

Begley, Máire; Gahan, Cormac G. M.; Hill, Colin

2002-01-01

Bile is one of many barriers that Listeria monocytogenes must overcome in the human gastrointestinal tract in order to infect and cause disease. We demonstrated that stationary-phase cultures of L. monocytogenes LO28 were able to tolerate concentrations of bovine, porcine, and human bile and bile acids well in excess of those encountered in vivo. Strain LO28 was relatively bile resistant compared with other clinical isolates of L. monocytogenes, as well as with Listeria innocua, Salmonella enterica serovar Typhimurium LT2, and Lactobacillus sakei. While exponential-phase L. monocytogenes LO28 cells were exquisitely sensitive to unconjugated bile acids, prior adaptation to sublethal levels of bile acids or heterologous stresses, such as acid, heat, salt, or sodium dodecyl sulfate (SDS), significantly enhanced bile resistance. This adaptive response was independent of protein synthesis, and in the cases of bile and SDS adaptation, occurred in seconds. In order to identify genetic loci involved in the bile tolerance phenotype of L. monocytogenes LO28, transposon (Tn917) and plasmid (pORI19) integration banks were screened for bile-sensitive mutants. The disrupted genes included a homologue of the capA locus required for capsule formation in Bacillus anthracis; a gene encoding the transcriptional regulator ZurR; a homologue of an Escherichia coli gene, lytB, involved in isoprenoid biosynthesis; a gene encoding a homologue of the Bacillus subtilis membrane protein YxiO; and a gene encoding an amino acid transporter with a putative role in pH homeostasis, gadE. Interestingly, all of the identified loci play putative roles in maintenance of the cell envelope or in stress responses. PMID:12450822

The effects of anesthesia and gender on intraocular pressure in lions (Panthera leo).

PubMed

Ofri, R; Horowitz, I; Jacobson, S; Kass, P H

1998-09-01

Intraocular pressure (IOP) was measured in a pride of 22 (11 males, 11 females) lions (Panthera leo) using a Schiotz tonometer. Two anesthetic protocols were used in the study. Lions in group I (n = 14) were anesthetized using xylazine, atropine sulfate, and ketamine. Lions in group II (n = 8) were anesthetized using ketamine and diazepam. Five sequential readings were taken from each eye of every lion. There were no significant differences in IOP between the two anesthetic groups, between left and right eyes, or over the five readings. The IOP was significantly higher in males than in females, controlling for age and weight. The mean (+/-SD) tonometer reading in 22 eyes of 11 male lions was 2.9 (+/-0.5) mm; with a 95% confidence interval (CI) of 1.6-4.5 mm. The mean tonometer reading in 22 eyes of 11 female lions was 4.0 (+/-0.7) mm, with a 95% CI of 1.8-6.3 mm. Using the 1955 Friedenwald human calibration table, the estimated mean IOP in 22 eyes of 11 male lions was 24.9 (+/-2.0) mm Hg, with a 95% CI of 20.4-29.4 mm Hg. The estimated mean IOP in 22 eyes of 11 female lions was 20.9 (+/-2.4) mm Hg, with a 95% CI of 15.6-26.3 mm Hg.

6-Gingerol Inhibits Growth of Colon Cancer Cell LoVo via Induction of G2/M Arrest

PubMed Central

Lin, Ching-Bin; Lin, Chun-Che; Tsay, Gregory J.

2012-01-01

6-Gingerol, a natural component of ginger, has been widely reported to possess antiinflammatory and antitumorigenic activities. Despite its potential efficacy against cancer, the anti-tumor mechanisms of 6-gingerol are complicated and remain sketchy. In the present study, we aimed to investigate the anti-tumor effects of 6-gingerol on colon cancer cells. Our results revealed that 6-gingerol treatment significantly reduced the cell viability of human colon cancer cell, LoVo, in a dose-dependent manner. Further flow cytometric analysis showed that 6-gingerol induced significant G2/M phase arrest and had slight influence on sub-G1 phase in LoVo cells. Therefore, levels of cyclins, cyclin-dependent kinases (CDKs), and their regulatory proteins involved in S-G2/M transition were investigated. Our findings revealed that levels of cyclin A, cyclin B1, and CDK1 were diminished; in contrast, levels of the negative cell cycle regulators p27Kip1 and p21Cip1 were increased in response to 6-gingerol treatment. In addition, 6-gingerol treatment elevated intracellular reactive oxygen species (ROS) and phosphorylation level of p53. These findings indicate that exposure of 6-gingerol may induce intracellular ROS and upregulate p53, p27Kip1, and p21Cip1 levels leading to consequent decrease of CDK1, cyclin A, and cyclin B1 as result of cell cycle arrest in LoVo cells. It would be suggested that 6-gingerol should be beneficial to treatment of colon cancer. PMID:22719783

6-Gingerol Inhibits Growth of Colon Cancer Cell LoVo via Induction of G2/M Arrest.

PubMed

Lin, Ching-Bin; Lin, Chun-Che; Tsay, Gregory J

2012-01-01

6-Gingerol, a natural component of ginger, has been widely reported to possess antiinflammatory and antitumorigenic activities. Despite its potential efficacy against cancer, the anti-tumor mechanisms of 6-gingerol are complicated and remain sketchy. In the present study, we aimed to investigate the anti-tumor effects of 6-gingerol on colon cancer cells. Our results revealed that 6-gingerol treatment significantly reduced the cell viability of human colon cancer cell, LoVo, in a dose-dependent manner. Further flow cytometric analysis showed that 6-gingerol induced significant G2/M phase arrest and had slight influence on sub-G1 phase in LoVo cells. Therefore, levels of cyclins, cyclin-dependent kinases (CDKs), and their regulatory proteins involved in S-G2/M transition were investigated. Our findings revealed that levels of cyclin A, cyclin B1, and CDK1 were diminished; in contrast, levels of the negative cell cycle regulators p27(Kip1) and p21(Cip1) were increased in response to 6-gingerol treatment. In addition, 6-gingerol treatment elevated intracellular reactive oxygen species (ROS) and phosphorylation level of p53. These findings indicate that exposure of 6-gingerol may induce intracellular ROS and upregulate p53, p27(Kip1), and p21(Cip1) levels leading to consequent decrease of CDK1, cyclin A, and cyclin B1 as result of cell cycle arrest in LoVo cells. It would be suggested that 6-gingerol should be beneficial to treatment of colon cancer.

HIGH-RESOLUTION SPECTROSCOPY OF EXTREMELY METAL-POOR STARS IN THE LEAST EVOLVED GALAXIES: LEO IV

DOE Office of Scientific and Technical Information (OSTI.GOV)

Simon, Joshua D.; McWilliam, Andrew; Thompson, Ian B.

2010-06-10

We present high-resolution Magellan/MIKE spectroscopy of the brightest star in the ultra-faint dwarf galaxy Leo IV. We measure an iron abundance of [Fe/H] = -3.2, adding to the rapidly growing sample of extremely metal-poor (EMP) stars being identified in Milky Way satellite galaxies. The star is enhanced in the {alpha} elements Mg, Ca, and Ti by {approx}0.3 dex, very similar to the typical Milky Way halo abundance pattern. All of the light and iron-peak elements follow the trends established by EMP halo stars, but the neutron-capture elements Ba and Sr are significantly underabundant. These results are quite similar to thosemore » found for stars in the ultra-faint dwarfs Ursa Major II, Coma Berenices, Booetes I, and Hercules, suggesting that the chemical evolution of the lowest-luminosity galaxies may be universal. The abundance pattern we observe is consistent with predictions for nucleosynthesis from a Population III supernova explosion. The extremely low metallicity of this star also supports the idea that a significant fraction ({approx}>10%) of the stars in the faintest dwarfs have metallicities below [Fe/H] = -3.0.« less

Degenerative myelopathy and vitamin A deficiency in a young black-maned lion (Panthera leo).

PubMed

Maratea, Kimberly A; Hooser, Stephen B; Ramos-Vara, José A

2006-11-01

Degenerative myelopathy and vitamin A deficiency were diagnosed in a 1-year-old, female, black-maned lion (Panthera leo). Diffuse white matter degeneration characterized by dilated myelin sheaths, Wallerian degeneration, and reactive astrocytosis was present at all levels of the spinal cord. With luxol fast blue-resyl echt violet stain, bilaterally symmetrical demyelination was observed in the fasciculus cuneatus of the cervical spinal cord and in peripheral white matter of cervical, thoracic, and lumbar segments. Additionally, the ventral gray columns and brain stem nuclei contained rare chromatolytic neurons with abnormal neurofilament accumulation. Leptomeninges of the cervical spinal cord were focally adhered to the dura and thickened by fibrosis and osseous metaplasia. Vitamin A deficiency was diagnosed based on hepatic vitamin A concentration of 1.71 microg/g dry weight. Adequate hepatic vitamin A concentration for yearling to adult domestic animals ranges between 150 and 1000 microg/g dry weight. Lesions were distinct from those previously described in young captive lions with vitamin A deficiency, which had thickened skull bones and cerebellar herniation. The pathogenesis of vitamin A-associated myelopathy in this lion may be similar to that described in adult cattle, which is believed to result from spinal cord compression secondary to elevated pressure of cerebrospinal fluid.

Visualizing whole-brain DTI tractography with GPU-based Tuboids and LoD management.

PubMed

Petrovic, Vid; Fallon, James; Kuester, Falko

2007-01-01

Diffusion Tensor Imaging (DTI) of the human brain, coupled with tractography techniques, enable the extraction of large-collections of three-dimensional tract pathways per subject. These pathways and pathway bundles represent the connectivity between different brain regions and are critical for the understanding of brain related diseases. A flexible and efficient GPU-based rendering technique for DTI tractography data is presented that addresses common performance bottlenecks and image-quality issues, allowing interactive render rates to be achieved on commodity hardware. An occlusion query-based pathway LoD management system for streamlines/streamtubes/tuboids is introduced that optimizes input geometry, vertex processing, and fragment processing loads, and helps reduce overdraw. The tuboid, a fully-shaded streamtube impostor constructed entirely on the GPU from streamline vertices, is also introduced. Unlike full streamtubes and other impostor constructs, tuboids require little to no preprocessing or extra space over the original streamline data. The supported fragment processing levels of detail range from texture-based draft shading to full raycast normal computation, Phong shading, environment mapping, and curvature-correct text labeling. The presented text labeling technique for tuboids provides adaptive, aesthetically pleasing labels that appear attached to the surface of the tubes. Furthermore, an occlusion query aggregating and scheduling scheme for tuboids is described that reduces the query overhead. Results for a tractography dataset are presented, and demonstrate that LoD-managed tuboids offer benefits over traditional streamtubes both in performance and appearance.

Solar rocket system concept analysis

NASA Technical Reports Server (NTRS)

Boddy, J. A.

1980-01-01

The use of solar energy to heat propellant for application to Earth orbital/planetary propulsion systems is of interest because of its performance capabilities. The achievable specific impulse values are approximately double those delivered by a chemical rocket system, and the thrust is at least an order of magnitude greater than that produced by a mercury bombardment ion propulsion thruster. The primary advantage the solar heater thruster has over a mercury ion bombardment system is that its significantly higher thrust permits a marked reduction in mission trip time. The development of the space transportation system, offers the opportunity to utilize the full performance potential of the solar rocket. The requirements for transfer from low Earth orbit (LEO) to geosynchronous equatorial orbit (GEO) was examined as the return trip, GEO to LEO, both with and without payload. Payload weights considered ranged from 2000 to 100,000 pounds. The performance of the solar rocket was compared with that provided by LO2-LH2, N2O4-MMH, and mercury ion bombardment systems.

Jet production in the CoLoRFulNNLO method: Event shapes in electron-positron collisions

NASA Astrophysics Data System (ADS)

Del Duca, Vittorio; Duhr, Claude; Kardos, Adam; Somogyi, Gábor; Szőr, Zoltán; Trócsányi, Zoltán; Tulipánt, Zoltán

2016-10-01

We present the CoLoRFulNNLO method to compute higher order radiative corrections to jet cross sections in perturbative QCD. We apply our method to the computation of event shape observables in electron-positron collisions at NNLO accuracy and validate our code by comparing our predictions to previous results in the literature. We also calculate for the first time jet cone energy fraction at NNLO.

On-board orbit determination for low thrust LEO-MEO transfer by Consider Kalman Filtering and multi-constellation GNSS

NASA Astrophysics Data System (ADS)

Menzione, Francesco; Renga, Alfredo; Grassi, Michele

2017-09-01

In the framework of the novel navigation scenario offered by the next generation satellite low thrust autonomous LEO-to-MEO orbit transfer, this study proposes and tests a GNSS based navigation system aimed at providing on-board precise and robust orbit determination strategy to override rising criticalities. The analysis introduces the challenging design issues to simultaneously deal with the variable orbit regime, the electric thrust control and the high orbit GNSS visibility conditions. The Consider Kalman Filtering approach is here proposed as the filtering scheme to process the GNSS raw data provided by a multi-antenna/multi-constellation receiver in presence of uncertain parameters affecting measurements, actuation and spacecraft physical properties. Filter robustness and achievable navigation accuracy are verified using a high fidelity simulation of the low-thrust rising scenario and performance are compared with the one of a standard Extended Kalman Filtering approach to highlight the advantages of the proposed solution. Performance assessment of the developed navigation solution is accomplished for different transfer phases.

Longitudinal tracking of subpopulation dynamics and molecular changes during LNCaP cell castration and identification of inhibitors that could target the PSA-/lo castration-resistant cells.

PubMed

Rycaj, Kiera; Cho, Eun Jeong; Liu, Xin; Chao, Hsueh-Ping; Liu, Bigang; Li, Qiuhui; Devkota, Ashwini K; Zhang, Dingxiao; Chen, Xin; Moore, John; Dalby, Kevin N; Tang, Dean G

2016-03-22

We have recently demonstrated that the undifferentiated PSA-/lo prostate cancer (PCa) cell population harbors self-renewing long-term tumor-propagating cells that are refractory to castration, thus representing a therapeutic target. Our goals here are, by using the same lineage-tracing reporter system, to track the dynamic changes of PSA-/lo and PSA+ cells upon castration in vitro, investigate the molecular changes accompanying persistent castration, and develop large numbers of PSA-/lo PCa cells for drug screening. To these ends, we treated LNCaP cells infected with the PSAP-GFP reporter with three regimens of castration, i.e., CDSS, CDSS plus bicalutamide, and MDV3100 continuously for up to ~21 months. We observed that in the first ~7 months, castration led to time-dependent increases in PSA-/lo cells, loss of AR and PSA expression, increased expression of cancer stem cell markers, and many other molecular changes. Meanwhile, castrated LNCaP cells became resistant to high concentrations of MDV3100, chemotherapeutic drugs, and other agents. However, targeted and medium-throughput library screening identified several kinase (e.g., IGF-1R, AKT, PI3K/mTOR, Syk, GSK3) inhibitors as well as the BCL2 inhibitor that could effectively sensitize the LNCaP-CRPC cells to killing. Of interest, LNCaP cells castrated for >7 months showed evidence of cyclic changes in AR and the mTOR/AKT signaling pathways potentially involving epigenetic mechanisms. These observations indicate that castration elicits numerous molecular changes and leads to enrichment of PSA-/lo PCa cells. The ability to generate large numbers of PSA-/lo PCa cells should allow future high-throughput screening to identify novel therapeutics that specifically target this population.

Longitudinal tracking of subpopulation dynamics and molecular changes during LNCaP cell castration and identification of inhibitors that could target the PSA−/lo castration-resistant cells

PubMed Central

Rycaj, Kiera; Cho, Eun Jeong; Liu, Xin; Chao, Hsueh-Ping; Liu, Bigang; Li, Qiuhui; Devkota, Ashwini K.; Zhang, Dingxiao; Chen, Xin; Moore, John; Dalby, Kevin N.; Tang, Dean G.

2016-01-01

We have recently demonstrated that the undifferentiated PSA−/lo prostate cancer (PCa) cell population harbors self-renewing long-term tumor-propagating cells that are refractory to castration, thus representing a therapeutic target. Our goals here are, by using the same lineage-tracing reporter system, to track the dynamic changes of PSA−/lo and PSA+ cells upon castration in vitro, investigate the molecular changes accompanying persistent castration, and develop large numbers of PSA−/lo PCa cells for drug screening. To these ends, we treated LNCaP cells infected with the PSAP-GFP reporter with three regimens of castration, i.e., CDSS, CDSS plus bicalutamide, and MDV3100 continuously for up to ~21 months. We observed that in the first ~7 months, castration led to time-dependent increases in PSA−/lo cells, loss of AR and PSA expression, increased expression of cancer stem cell markers, and many other molecular changes. Meanwhile, castrated LNCaP cells became resistant to high concentrations of MDV3100, chemotherapeutic drugs, and other agents. However, targeted and medium-throughput library screening identified several kinase (e.g., IGF-1R, AKT, PI3K/mTOR, Syk, GSK3) inhibitors as well as the BCL2 inhibitor that could effectively sensitize the LNCaP-CRPC cells to killing. Of interest, LNCaP cells castrated for >7 months showed evidence of cyclic changes in AR and the mTOR/AKT signaling pathways potentially involving epigenetic mechanisms. These observations indicate that castration elicits numerous molecular changes and leads to enrichment of PSA−/lo PCa cells. The ability to generate large numbers of PSA−/lo PCa cells should allow future high-throughput screening to identify novel therapeutics that specifically target this population. PMID:26871947

Optical and X-ray studies of chromospherically active stars: FR Cancri, HD 95559 and LO Pegasi

NASA Technical Reports Server (NTRS)

Pandey, J. C.; Singh, K. P.; Drake, S. A.; Sagar, R.

2005-01-01

We present a multiwavelength study of three chromospherically active stars, namely FR Cnc (= BD +16 degrees 1753), HD 95559 and LO Peg (=BD +22 degrees 4409), including newly obtained optical photometry, (for FR Cnc) low-resolution optical spectroscopy, as well as archival IR and X-ray observations. The BVR photometry carried out during the years 2001 - 2004 has found significant photometric variability to be present in all three stars. For FR Cnc, a photometric period 0.826685 +/- 0.000034 d has been established. The strong variation in the phase and amplitude of the FR Cnc light curves when folded on this period implies the presence of evolving and migrating spots or spot groups on its surface. Two independent spots with migration periods of 0.97 and 0.93 years respectively are inferred. The photometry of HD 95559 suggests the formation of a spot (group) during the interval of our observations. We infer the existence of two independent spots or groups in the photosphere of LO Peg, one of which has a migration period of 1.12 years. The optical spectroscopy of FR Cnc carried out during 2002-2003, reveals the presence of strong and variable Ca I1 H and K, H(sub beta) and H(sub alpha) emission features indicative of high level of chromospheric activity. The value of 5.3 for the ratio of the excess emission in H(sub alpha) to H(sub beta), EH(sub alpha)/EH(sub beta), suggests that the chromospheric emission may arise from an extended off-limb region. We have searched for the presence of color excesses in the near-IR JHK bands of these stars using 2MASS data, but none of them appear to have any significant color excess. We have also analyzed archival X-ray observations of HD 95559 and LO Peg carried out by with the ROSAT observatory. The best fit models to their X-ray spectra imply the presence of two coronal plasma components of differing temperatures and with sub-solar metal abundances. The inferred emission measures and temperatures of these systems are similar to

Seasonality and Paleoecology of the Late Cretaceous Multi-Taxa Vertebrate Assemblage of “Lo Hueco” (Central Eastern Spain)

PubMed Central

Domingo, Laura; Barroso-Barcenilla, Fernando; Cambra-Moo, Oscar

2015-01-01

Isotopic studies of multi-taxa terrestrial vertebrate assemblages allow determination of paleoclimatic and paleoecological aspects on account of the different information supplied by each taxon. The late Campanian-early Maastrichtian “Lo Hueco” Fossil-Lagerstätte (central eastern Spain), located at a subtropical paleolatitude of ~31°N, constitutes an ideal setting to carry out this task due to its abundant and diverse vertebrate assemblage. Local δ18OPO4 values estimated from δ18OPO4 values of theropods, sauropods, crocodyliforms, and turtles are close to δ18OH2O values observed at modern subtropical latitudes. Theropod δ18OH2O values are lower than those shown by crocodyliforms and turtles, indicating that terrestrial endothermic taxa record δ18OH2O values throughout the year, whereas semiaquatic ectothermic taxa δ18OH2O values represent local meteoric waters over a shorter time period when conditions are favorable for bioapatite synthesis (warm season). Temperatures calculated by combining theropod, crocodyliform, and turtle δ18OH2O values and gar δ18OPO4 have enabled us to estimate seasonal variability as the difference between mean annual temperature (MAT, yielded by theropods) and temperature of the warmest months (TWMs, provided by crocodyliforms and turtles). ΔTWMs-MAT value does not point to a significantly different seasonal thermal variability when compared to modern coastal subtropical meteorological stations and Late Cretaceous rudists from eastern Tethys. Bioapatite and bulk organic matter δ13C values point to a C3 environment in the “Lo Hueco” area. The estimated fractionation between sauropod enamel and diet is ~15‰. While waiting for paleoecological information yielded by the ongoing morphological study of the “Lo Hueco” crocodyliforms, δ13C and δ18OCO3 results point to incorporation of food items with brackish influence, but preferential ingestion of freshwater. “Lo Hueco” turtles showed the lowest δ13C and δ18OCO3

Diagnosing the Neutral Interstellar Gas Flow at 1 AU with IBEX-Lo

NASA Astrophysics Data System (ADS)

Möbius, E.; Kucharek, H.; Clark, G.; O'Neill, M.; Petersen, L.; Bzowski, M.; Saul, L.; Wurz, P.; Fuselier, S. A.; Izmodenov, V. V.; McComas, D. J.; Müller, H. R.; Alexashov, D. B.

2009-08-01

Every year in fall and spring the Interstellar Boundary Explorer (IBEX) will observe directly the interstellar gas flow at 1 AU over periods of several months. The IBEX-Lo sensor employs a powerful triple time-of-flight mass spectrometer. It can distinguish and image the O and He flow distributions in the northern fall and spring, making use of sensor viewing perpendicular to the Sun-pointing spin axis. To effectively image the narrow flow distributions IBEX-Lo has a high angular resolution quadrant in its collimator. This quadrant is employed selectively for the interstellar gas flow viewing in the spring by electrostatically shutting off the remainder of the aperture. The operational scenarios, the expected data, and the necessary modeling to extract the interstellar parameters and the conditions in the heliospheric boundary are described. The combination of two key interstellar species will facilitate a direct comparison of the pristine interstellar flow, represented by He, which has not been altered in the heliospheric boundary region, with a flow that is processed in the outer heliosheath, represented by O. The O flow distribution consists of a depleted pristine component and decelerated and heated neutrals. Extracting the latter so-called secondary component of interstellar neutrals will provide quantitative constraints for several important parameters of the heliosheath interaction in current global heliospheric models. Finding the fraction and width of the secondary component yields an independent value for the global filtration factor of species, such as O and H. Thus far filtration can only be inferred, barring observations in the local interstellar cloud proper. The direction of the secondary component will provide independent information on the interstellar magnetic field strength and orientation, which has been inferred from SOHO SWAN Ly- α backscattering observations and the two Voyager crossings of the termination shock.

Needle biopsy for hepatic vitamin A levels in lions (Panthera leo).

PubMed

Shamir, Merav H; Rubin, Gal; Aizenberg, Zachi; Berkovich, Zipi; Reifen, Ram; Horowitz, Igal; Bdolah-Abram, Tali; Aroch, Itamar

2012-06-01

Hypovitaminosis A (HA)-related skull malformations resulting in neurologic abnormalities and death have been, and still are, reported in captive lions (Panthera leo) worldwide. Liver vitamin A (VA) concentration is the most reliable indicator of animals' VA status, and its assessment is essential in prevention and treatment of HA in lions. A percutaneous needle liver biopsy using high-performance liquid chromatography ultraviolet retinoid analysis for VA concentration measurement was validated. It was first assessed in vitro using chicken liver. Later, the safety and feasibility of ultrasound-guided percutaneous needle liver biopsy was assessed in living lions. Hepatic VA concentrations in lion liver were measured using the above laboratory method. Mean chicken hepatic VA concentration in needle biopsy (NB) and wedge biopsy (WB) of the same liver lobes were 108.66 and 60.89 microg/g wet tissue, respectively, and were significantly (P = 0.03) correlated (r = 0.74). The calculated linear regression for predicting VA concentration in WB using NB VA for chicken liver was 25.194 + 0.3234x NB (microg/g). Four ultrasound-guided percutaneous needle liver biopsies were obtained from each of the four lions under general anesthesia. Mean hepatic VA concentration was 8.25 microg/g wet tissue (range 1.43-25.29 microg/g). Mean serum VA concentration, measured in these four lions was 1,011.1 nmol/L with a standard deviation of 337.91 nmol/L (range 590.26-1,077.2 nmol/L). The lions recovered uneventfully, and no complications were observed during a 4-yr follow-up period. In conclusion, the percutaneous needle liver biopsy technique is a reliable, practical, safe tool for obtaining liver tissue samples antemortem for assessment of the VA status in lions and can be used in future studies.

Eomesodermin(lo) CTLA4(hi) Alloreactive CD8+ Memory T Cells Are Associated With Prolonged Renal Transplant Survival Induced by Regulatory Dendritic Cell Infusion in CTLA4 Immunoglobulin-Treated Nonhuman Primates.

PubMed

Ezzelarab, Mohamed B; Lu, Lien; Guo, Hao; Zahorchak, Alan F; Shufesky, William F; Cooper, David K C; Morelli, Adrian E; Thomson, Angus W

2016-01-01

Memory T cells (Tmem), particularly those resistant to costimulation blockade (CB), are a major barrier to transplant tolerance. The transcription factor Eomesodermin (Eomes) is critical for Tmem development and maintenance, but its expression by alloactivated T cells has not been examined in nonhuman primates. We evaluated Eomes and coinhibitory cytotoxic T lymphocyte antigen-4 (CTLA4) expression by alloactivated rhesus monkey T cells in the presence of CTLA4 immunoglobulin, both in vitro and in renal allograft recipients treated with CTLA4Ig, with or without regulatory dendritic cell (DCreg) infusion. In normal monkeys, CD8+ T cells expressed significantly more Eomes than CD4+ T cells. By contrast, CD8+ T cells displayed minimal CTLA4. Among T cell subsets, central Tmem (Tcm) expressed the highest levels of Eomes. Notably, Eomes(lo)CTLA4(hi) cells displayed higher levels of CD25 and Foxp3 than Eomes(hi)CTLA4(lo) CD8+ T cells. After allostimulation, distinct proliferating Eomes(lo)CTLA4(hi) and Eomes(hi)CTLA4(lo) CD8+ T cell populations were identified, with a high proportion of Tcm being Eomes(lo)CTLA4(hi). CB with CTLA4Ig during allostimulation of CD8+ T cells reduced CTLA4 but not Eomes expression, significantly reducing Eomes(lo)CTLA4(hi) cells. After transplantation with CB and rapamycin, donor-reactive Eomes(lo)CTLA4(hi) CD8+ T cells were reduced. However, in monkeys also given DCreg, absolute numbers of these cells were elevated significantly. Low Eomes and high CTLA4 expression by donor-reactive CD8+ Tmem is associated with prolonged renal allograft survival induced by DCreg infusion in CTLA4Ig-treated monkeys. Prolonged allograft survival associated with DCreg infusion may be related to maintenance of donor-reactive Eomes(lo)CTLA4(hi) Tcm.

EETs Attenuate Ox-LDL-Induced LTB4 Production and Activity by Inhibiting p38 MAPK Phosphorylation and 5-LO/BLT1 Receptor Expression in Rat Pulmonary Arterial Endothelial Cells.

PubMed

Jiang, Jun-xia; Zhang, Shui-juan; Xiong, Yao-kang; Jia, Yong-liang; Sun, Yan-hong; Lin, Xi-xi; Shen, Hui-juan; Xie, Qiang-min; Yan, Xiao-feng

2015-01-01

Cytochrome P-450 epoxygenase (EPOX)-derived epoxyeicosatrienoic acids (EETs), 5-lipoxygenase (5-LO), and leukotriene B4 (LTB4), the product of 5-LO, all play a pivotal role in the vascular inflammatory process. We have previously shown that EETs can alleviate oxidized low-density lipoprotein (ox-LDL)-induced endothelial inflammation in primary rat pulmonary artery endothelial cells (RPAECs). Here, we investigated whether ox-LDL can promote LTB4 production through the 5-LO pathway. We further explored how exogenous EETs influence ox-LDL-induced LTB4 production and activity. We found that treatment with ox-LDL increased the production of LTB4 and further led to the expression and release of both monocyte chemoattractant protein-1 (MCP-1/CCL2) and intercellular adhesion molecule-1 (ICAM-1). All of the above ox-LDL-induced changes were attenuated by the presence of 11,12-EET and 14,15-EET, as these molecules inhibited the 5-LO pathway. Furthermore, the LTB4 receptor 1 (BLT1 receptor) antagonist U75302 attenuated ox-LDL-induced ICAM-1 and MCP-1/CCL2 expression and production, whereas LY255283, a LTB4 receptor 2 (BLT2 receptor) antagonist, produced no such effects. Moreover, in RPAECs, we demonstrated that the increased expression of 5-LO and BLT1 following ox-LDL treatment resulted from the activation of nuclear factor-κB (NF-κB) via the p38 mitogen-activated protein kinase (MAPK) pathway. Our results indicated that EETs suppress ox-LDL-induced LTB4 production and subsequent inflammatory responses by downregulating the 5-LO/BLT1 receptor pathway, in which p38 MAPK phosphorylation activates NF-κB. These results suggest that the metabolism of arachidonic acid via the 5-LO and EPOX pathways may present a mutual constraint on the physiological regulation of vascular endothelial cells.

EETs Attenuate Ox-LDL-Induced LTB4 Production and Activity by Inhibiting p38 MAPK Phosphorylation and 5-LO/BLT1 Receptor Expression in Rat Pulmonary Arterial Endothelial Cells

PubMed Central

Xiong, Yao-kang; Jia, Yong-liang; Sun, Yan-hong; Lin, Xi-xi; Shen, Hui-juan; Xie, Qiang-min; Yan, Xiao-feng

2015-01-01

Cytochrome P-450 epoxygenase (EPOX)-derived epoxyeicosatrienoic acids (EETs), 5-lipoxygenase (5-LO), and leukotriene B4 (LTB4), the product of 5-LO, all play a pivotal role in the vascular inflammatory process. We have previously shown that EETs can alleviate oxidized low-density lipoprotein (ox-LDL)-induced endothelial inflammation in primary rat pulmonary artery endothelial cells (RPAECs). Here, we investigated whether ox-LDL can promote LTB4 production through the 5-LO pathway. We further explored how exogenous EETs influence ox-LDL-induced LTB4 production and activity. We found that treatment with ox-LDL increased the production of LTB4 and further led to the expression and release of both monocyte chemoattractant protein-1 (MCP-1/CCL2) and intercellular adhesion molecule-1 (ICAM-1). All of the above ox-LDL-induced changes were attenuated by the presence of 11,12-EET and 14,15-EET, as these molecules inhibited the 5-LO pathway. Furthermore, the LTB4 receptor 1 (BLT1 receptor) antagonist U75302 attenuated ox-LDL-induced ICAM-1 and MCP-1/CCL2 expression and production, whereas LY255283, a LTB4 receptor 2 (BLT2 receptor) antagonist, produced no such effects. Moreover, in RPAECs, we demonstrated that the increased expression of 5-LO and BLT1 following ox-LDL treatment resulted from the activation of nuclear factor-κB (NF-κB) via the p38 mitogen-activated protein kinase (MAPK) pathway. Our results indicated that EETs suppress ox-LDL-induced LTB4 production and subsequent inflammatory responses by downregulating the 5-LO/BLT1 receptor pathway, in which p38 MAPK phosphorylation activates NF-κB. These results suggest that the metabolism of arachidonic acid via the 5-LO and EPOX pathways may present a mutual constraint on the physiological regulation of vascular endothelial cells. PMID:26035589

Space Radiation Environment Prediction for VLSI microelectronics devices onboard a LEO Satellite using OMERE-Trad Software

NASA Astrophysics Data System (ADS)

Sajid, Muhammad

This tutorial/survey paper presents the assessment/determination of level of hazard/threat to emerging microelectronics devices in Low Earth Orbit (LEO) space radiation environment with perigee at 300 Km, apogee at 600Km altitude having different orbital inclinations to predict the reliability of onboard Bulk Built-In Current Sensor (BBICS) fabricated in 350nm technology node at OptMA Lab. UFMG Brazil. In this context, the various parameters for space radiation environment have been analyzed to characterize the ionizing radiation environment effects on proposed BBICS. The Space radiation environment has been modeled in the form of particles trapped in Van-Allen radiation belts(RBs), Energetic Solar Particles Events (ESPE) and Galactic Cosmic Rays (GCR) where as its potential effects on Device- Under-Test (DUT) has been predicted in terms of Total Ionizing Dose (TID), Single-Event Effects (SEE) and Displacement Damage Dose (DDD). Finally, the required mitigation techniques including necessary shielding requirements to avoid undesirable effects of radiation environment at device level has been estimated /determined with assumed standard thickness of Aluminum shielding. In order to evaluate space radiation environment and analyze energetic particles effects on BBICS, OMERE toolkit developed by TRAD was utilized.

Diagnosis and surgical treatment of a Chiari I-like malformation in an African lion (Panthera leo).

PubMed

McCain, Stephanie; Souza, Marcy; Ramsay, Ed; Schumacher, Juergen; Hecht, Silke; Thomas, William

2008-09-01

A 13-mo-old intact male African lion (Panthera leo) presented with a 3-mo history of lethargy, ventral flexion of the neck, abnormal vocalization, and ataxia. Hemogram and serum biochemistries were within normal limits except for the presence of hypokalemia (2.7 mEq/L) and hypochloridemia (108 mEq/L). When no improvement was noted with oral potassium gluconate supplementation, a computed tomography scan of the brain and skull was performed, and no abnormalities were noted. However, magnetic resonance imaging detected occipital bone thickening, crowding of the caudal cranial fossa with cerebellar compression and herniation, and cervical syringohydromyelia, which was consistent with a Chiari I-like malformation. Foramen magnum decompression was performed to relieve the compression of the cerebellum. The animal recovered well with subsequent resolution of clinical signs. Hypovitaminosis A has been proposed previously as the underlying etiology for this malformation in lions with similar clinical presentations. This lion's serum and liver vitamin A concentrations were low (100 ng/ml and 25.31 microg/g, respectively) compared to concentrations reported for domestic carnivores and support hypovitaminosis A as the underlying cause of this animal's Chiari I-like malformation.