20 CFR 416.1238 - Exclusion of certain housing assistance.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Exclusion of certain housing assistance. 416.1238 Section 416.1238 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Resources and Exclusions § 416.1238 Exclusion of certain housing...

Planck 2015 results: VI. LFI mapmaking

DOE PAGES

Ade, P. A. R.; Aghanim, N.; Ashdown, M.; ...

2016-09-20

This article describes the mapmaking procedure applied to Planck Low Frequency Instrument (LFI) data. The mapmaking step takes as input the calibrated timelines and pointing information. The main products are sky maps of I, Q, and U Stokes components. For the first time, we present polarization maps at LFI frequencies. The mapmaking algorithm is based on a destriping technique, which is enhanced with a noise prior. The Galactic region is masked to reduce errors arising from bandpass mismatch and high signal gradients. We apply horn-uniform radiometer weights to reduce the effects of beam-shape mismatch. The algorithm is the same asmore » used for the 2013 release, apart from small changes in parameter settings. We validate the procedure through simulations. Special emphasis is put on the control of systematics, which is particularly important for accurate polarization analysis. We also produce low-resolution versions of the maps and corresponding noise covariance matrices. These serve as input in later analysis steps and parameter estimation. The noise covariance matrices are validated through noise Monte Carlo simulations. The residual noise in the map products is characterized through analysis of half-ring maps, noise covariance matrices, and simulations.« less

Planck 2015 results. VI. LFI mapmaking

NASA Astrophysics Data System (ADS)

Planck Collaboration; Ade, P. A. R.; Aghanim, N.; Ashdown, M.; Aumont, J.; Baccigalupi, C.; Banday, A. J.; Barreiro, R. B.; Bartolo, N.; Battaner, E.; Benabed, K.; Benoît, A.; Benoit-Lévy, A.; Bernard, J.-P.; Bersanelli, M.; Bielewicz, P.; Bonaldi, A.; Bonavera, L.; Bond, J. R.; Borrill, J.; Bouchet, F. R.; Bucher, M.; Burigana, C.; Butler, R. C.; Calabrese, E.; Cardoso, J.-F.; Catalano, A.; Chamballu, A.; Chary, R.-R.; Christensen, P. R.; Colombi, S.; Colombo, L. P. L.; Crill, B. P.; Curto, A.; Cuttaia, F.; Danese, L.; Davies, R. D.; Davis, R. J.; de Bernardis, P.; de Rosa, A.; de Zotti, G.; Delabrouille, J.; Dickinson, C.; Diego, J. M.; Dole, H.; Donzelli, S.; Doré, O.; Douspis, M.; Ducout, A.; Dupac, X.; Efstathiou, G.; Elsner, F.; Enßlin, T. A.; Eriksen, H. K.; Fergusson, J.; Finelli, F.; Forni, O.; Frailis, M.; Franceschi, E.; Frejsel, A.; Galeotta, S.; Galli, S.; Ganga, K.; Giard, M.; Giraud-Héraud, Y.; Gjerløw, E.; González-Nuevo, J.; Górski, K. M.; Gratton, S.; Gregorio, A.; Gruppuso, A.; Hansen, F. K.; Hanson, D.; Harrison, D. L.; Henrot-Versillé, S.; Herranz, D.; Hildebrandt, S. R.; Hivon, E.; Hobson, M.; Holmes, W. A.; Hornstrup, A.; Hovest, W.; Huffenberger, K. M.; Hurier, G.; Jaffe, A. H.; Jaffe, T. R.; Juvela, M.; Keihänen, E.; Keskitalo, R.; Kiiveri, K.; Kisner, T. S.; Knoche, J.; Kunz, M.; Kurki-Suonio, H.; Lähteenmäki, A.; Lamarre, J.-M.; Lasenby, A.; Lattanzi, M.; Lawrence, C. R.; Leahy, J. P.; Leonardi, R.; Lesgourgues, J.; Levrier, F.; Liguori, M.; Lilje, P. B.; Linden-Vørnle, M.; Lindholm, V.; López-Caniego, M.; Lubin, P. M.; Macías-Pérez, J. F.; Maggio, G.; Maino, D.; Mandolesi, N.; Mangilli, A.; Martin, P. G.; Martínez-González, E.; Masi, S.; Matarrese, S.; Mazzotta, P.; McGehee, P.; Meinhold, P. R.; Melchiorri, A.; Mendes, L.; Mennella, A.; Migliaccio, M.; Mitra, S.; Montier, L.; Morgante, G.; Mortlock, D.; Moss, A.; Munshi, D.; Murphy, J. A.; Naselsky, P.; Nati, F.; Natoli, P.; Netterfield, C. B.; Nørgaard-Nielsen, H. U.; Novikov, D.; Novikov, I.; Paci, F.; Pagano, L.; Paoletti, D.; Partridge, B.; Pasian, F.; Patanchon, G.; Pearson, T. J.; Perdereau, O.; Perotto, L.; Perrotta, F.; Pettorino, V.; Pierpaoli, E.; Pietrobon, D.; Pointecouteau, E.; Polenta, G.; Pratt, G. W.; Prézeau, G.; Prunet, S.; Puget, J.-L.; Rachen, J. P.; Rebolo, R.; Reinecke, M.; Remazeilles, M.; Renzi, A.; Rocha, G.; Rosset, C.; Rossetti, M.; Roudier, G.; Rubiño-Martín, J. A.; Rusholme, B.; Sandri, M.; Santos, D.; Savelainen, M.; Scott, D.; Seiffert, M. D.; Shellard, E. P. S.; Spencer, L. D.; Stolyarov, V.; Stompor, R.; Sutton, D.; Suur-Uski, A.-S.; Sygnet, J.-F.; Tauber, J. A.; Terenzi, L.; Toffolatti, L.; Tomasi, M.; Tristram, M.; Tucci, M.; Tuovinen, J.; Valenziano, L.; Valiviita, J.; Van Tent, B.; Vassallo, T.; Vielva, P.; Villa, F.; Wade, L. A.; Wandelt, B. D.; Watson, R.; Wehus, I. K.; Yvon, D.; Zacchei, A.; Zonca, A.

2016-09-01

This paper describes the mapmaking procedure applied to Planck Low Frequency Instrument (LFI) data. The mapmaking step takes as input the calibrated timelines and pointing information. The main products are sky maps of I, Q, and U Stokes components. For the first time, we present polarization maps at LFI frequencies. The mapmaking algorithm is based on a destriping technique, which is enhanced with a noise prior. The Galactic region is masked to reduce errors arising from bandpass mismatch and high signal gradients. We apply horn-uniform radiometer weights to reduce the effects of beam-shape mismatch. The algorithm is the same as used for the 2013 release, apart from small changes in parameter settings. We validate the procedure through simulations. Special emphasis is put on the control of systematics, which is particularly important for accurate polarization analysis. We also produce low-resolution versions of the maps and corresponding noise covariance matrices. These serve as input in later analysis steps and parameter estimation. The noise covariance matrices are validated through noise Monte Carlo simulations. The residual noise in the map products is characterized through analysis of half-ring maps, noise covariance matrices, and simulations.

12 CFR 1238.8 - Additional implementing action.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 12 Banks and Banking 10 2014-01-01 2014-01-01 false Additional implementing action. 1238.8 Section 1238.8 Banks and Banking FEDERAL HOUSING FINANCE AGENCY ENTITY REGULATIONS STRESS TESTING OF REGULATED..., require any regulated entity not subject to this part to conduct stress testing hereunder; and from time...

26 CFR 1.1238-1 - Amortization in excess of depreciation.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 26 Internal Revenue 11 2010-04-01 2010-04-01 true Amortization in excess of depreciation. 1.1238-1... Amortization in excess of depreciation. (a) In general. Section 1238 provides that if a taxpayer is entitled to... amortization deduction exceeds normal depreciation. Thus, under section 1238 gain from a sale or exchange of...

40 CFR 86.1238-96 - Hot soak test.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 20 2013-07-01 2013-07-01 false Hot soak test. 86.1238-96 Section 86... Methanol-Fueled Heavy-Duty Vehicles § 86.1238-96 Hot soak test. (a)(1) Gasoline- and methanol-fueled vehicles. For gasoline- and methanol-fueled vehicles, the hot soak test shall be conducted immediately...

40 CFR 86.1238-96 - Hot soak test.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 20 2012-07-01 2012-07-01 false Hot soak test. 86.1238-96 Section 86... Methanol-Fueled Heavy-Duty Vehicles § 86.1238-96 Hot soak test. (a)(1) Gasoline- and methanol-fueled vehicles. For gasoline- and methanol-fueled vehicles, the hot soak test shall be conducted immediately...

40 CFR 86.1238-96 - Hot soak test.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 19 2010-07-01 2010-07-01 false Hot soak test. 86.1238-96 Section 86... Methanol-Fueled Heavy-Duty Vehicles § 86.1238-96 Hot soak test. (a)(1) Gasoline- and methanol-fueled vehicles. For gasoline- and methanol-fueled vehicles, the hot soak test shall be conducted immediately...

40 CFR 86.1238-96 - Hot soak test.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 19 2011-07-01 2011-07-01 false Hot soak test. 86.1238-96 Section 86... Methanol-Fueled Heavy-Duty Vehicles § 86.1238-96 Hot soak test. (a)(1) Gasoline- and methanol-fueled vehicles. For gasoline- and methanol-fueled vehicles, the hot soak test shall be conducted immediately...

20 CFR 416.1238 - Exclusion of certain housing assistance.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Exclusion of certain housing assistance. 416.1238 Section 416.1238 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME... assistance. The value of any assistance paid with respect to a dwelling under the statutes listed in § 416...

36 CFR 1238.20 - How must microform records be stored?

Code of Federal Regulations, 2011 CFR

2011-07-01

... specified in ISO 18911 and ANSI/PIMA IT9.2 (both incorporated by reference, see § 1238.5), except that the... may consult Life Expectance (LE) guidelines in ISO 18901 (incorporated by reference, see § 1238.5). ...

40 CFR 80.1238 - How is a refinery's or importer's average benzene concentration determined?

Code of Federal Regulations, 2014 CFR

2014-07-01

... average benzene concentration determined? 80.1238 Section 80.1238 Protection of Environment ENVIRONMENTAL... Benzene Gasoline Benzene Requirements § 80.1238 How is a refinery's or importer's average benzene concentration determined? (a) The average benzene concentration of gasoline produced at a refinery or imported...

40 CFR 80.1238 - How is a refinery's or importer's average benzene concentration determined?

Code of Federal Regulations, 2010 CFR

2010-07-01

... average benzene concentration determined? 80.1238 Section 80.1238 Protection of Environment ENVIRONMENTAL... Benzene Gasoline Benzene Requirements § 80.1238 How is a refinery's or importer's average benzene concentration determined? (a) The average benzene concentration of gasoline produced at a refinery or imported...

40 CFR 80.1238 - How is a refinery's or importer's average benzene concentration determined?

Code of Federal Regulations, 2013 CFR

2013-07-01

... average benzene concentration determined? 80.1238 Section 80.1238 Protection of Environment ENVIRONMENTAL... Benzene Gasoline Benzene Requirements § 80.1238 How is a refinery's or importer's average benzene concentration determined? (a) The average benzene concentration of gasoline produced at a refinery or imported...

40 CFR 80.1238 - How is a refinery's or importer's average benzene concentration determined?

Code of Federal Regulations, 2012 CFR

2012-07-01

... average benzene concentration determined? 80.1238 Section 80.1238 Protection of Environment ENVIRONMENTAL... Benzene Gasoline Benzene Requirements § 80.1238 How is a refinery's or importer's average benzene concentration determined? (a) The average benzene concentration of gasoline produced at a refinery or imported...

40 CFR 80.1238 - How is a refinery's or importer's average benzene concentration determined?

Code of Federal Regulations, 2011 CFR

2011-07-01

... average benzene concentration determined? 80.1238 Section 80.1238 Protection of Environment ENVIRONMENTAL... Benzene Gasoline Benzene Requirements § 80.1238 How is a refinery's or importer's average benzene concentration determined? (a) The average benzene concentration of gasoline produced at a refinery or imported...

12 CFR 1238.6 - Post-assessment actions by regulated entities.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 12 Banks and Banking 10 2014-01-01 2014-01-01 false Post-assessment actions by regulated entities... TESTING OF REGULATED ENTITIES § 1238.6 Post-assessment actions by regulated entities. Each regulated entity shall take the results of the stress test conducted under § 1238.3 into account in making changes...

12 CFR 1238.2 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Banking FEDERAL HOUSING FINANCE AGENCY ENTITY REGULATIONS STRESS TESTING OF REGULATED ENTITIES § 1238.2... 12 U.S.C. 4511. Planning horizon means the period of time over which the stress projections must... financial conditions used in the regulated entities' stress tests, including baseline, adverse, and severely...

Planck 2013 results. V. LFI calibration

NASA Astrophysics Data System (ADS)

Planck Collaboration; Aghanim, N.; Armitage-Caplan, C.; Arnaud, M.; Ashdown, M.; Atrio-Barandela, F.; Aumont, J.; Baccigalupi, C.; Banday, A. J.; Barreiro, R. B.; Battaner, E.; Benabed, K.; Benoît, A.; Benoit-Lévy, A.; Bernard, J.-P.; Bersanelli, M.; Bielewicz, P.; Bobin, J.; Bock, J. J.; Bonaldi, A.; Bonavera, L.; Bond, J. R.; Borrill, J.; Bouchet, F. R.; Bridges, M.; Bucher, M.; Burigana, C.; Butler, R. C.; Cappellini, B.; Cardoso, J.-F.; Catalano, A.; Chamballu, A.; Chen, X.; Chiang, L.-Y.; Christensen, P. R.; Church, S.; Colombi, S.; Colombo, L. P. L.; Crill, B. P.; Curto, A.; Cuttaia, F.; Danese, L.; Davies, R. D.; Davis, R. J.; de Bernardis, P.; de Rosa, A.; de Zotti, G.; Delabrouille, J.; Dickinson, C.; Diego, J. M.; Dole, H.; Donzelli, S.; Doré, O.; Douspis, M.; Dupac, X.; Efstathiou, G.; Enßlin, T. A.; Eriksen, H. K.; Finelli, F.; Forni, O.; Frailis, M.; Franceschi, E.; Gaier, T. C.; Galeotta, S.; Ganga, K.; Giard, M.; Giardino, G.; Giraud-Héraud, Y.; Gjerløw, E.; González-Nuevo, J.; Górski, K. M.; Gratton, S.; Gregorio, A.; Gruppuso, A.; Hansen, F. K.; Hanson, D.; Harrison, D.; Henrot-Versillé, S.; Hernández-Monteagudo, C.; Herranz, D.; Hildebrandt, S. R.; Hivon, E.; Hobson, M.; Holmes, W. A.; Hornstrup, A.; Hovest, W.; Huffenberger, K. M.; Jaffe, A. H.; Jaffe, T. R.; Jewell, J.; Jones, W. C.; Juvela, M.; Kangaslahti, P.; Keihänen, E.; Keskitalo, R.; Kisner, T. S.; Knoche, J.; Knox, L.; Kunz, M.; Kurki-Suonio, H.; Lagache, G.; Lähteenmäki, A.; Lamarre, J.-M.; Lasenby, A.; Laureijs, R. J.; Lawrence, C. R.; Leach, S.; Leahy, J. P.; Leonardi, R.; Lesgourgues, J.; Liguori, M.; Lilje, P. B.; Linden-Vørnle, M.; López-Caniego, M.; Lubin, P. M.; Macías-Pérez, J. F.; Maino, D.; Mandolesi, N.; Maris, M.; Marshall, D. J.; Martin, P. G.; Martínez-González, E.; Masi, S.; Massardi, M.; Matarrese, S.; Matthai, F.; Mazzotta, P.; Meinhold, P. R.; Melchiorri, A.; Mendes, L.; Mennella, A.; Migliaccio, M.; Mitra, S.; Moneti, A.; Montier, L.; Morgante, G.; Mortlock, D.; Moss, A.; Munshi, D.; Naselsky, P.; Natoli, P.; Netterfield, C. B.; Nørgaard-Nielsen, H. U.; Novikov, D.; Novikov, I.; O'Dwyer, I. J.; Osborne, S.; Paci, F.; Pagano, L.; Paladini, R.; Paoletti, D.; Partridge, B.; Pasian, F.; Patanchon, G.; Pearson, D.; Peel, M.; Perdereau, O.; Perotto, L.; Perrotta, F.; Pierpaoli, E.; Pietrobon, D.; Plaszczynski, S.; Pointecouteau, E.; Polenta, G.; Ponthieu, N.; Popa, L.; Poutanen, T.; Pratt, G. W.; Prézeau, G.; Prunet, S.; Puget, J.-L.; Rachen, J. P.; Rebolo, R.; Reinecke, M.; Remazeilles, M.; Ricciardi, S.; Riller, T.; Rocha, G.; Rosset, C.; Rossetti, M.; Roudier, G.; Rubiño-Martín, J. A.; Rusholme, B.; Sandri, M.; Santos, D.; Scott, D.; Seiffert, M. D.; Shellard, E. P. S.; Spencer, L. D.; Starck, J.-L.; Stolyarov, V.; Stompor, R.; Sureau, F.; Sutton, D.; Suur-Uski, A.-S.; Sygnet, J.-F.; Tauber, J. A.; Tavagnacco, D.; Terenzi, L.; Toffolatti, L.; Tomasi, M.; Tristram, M.; Tucci, M.; Tuovinen, J.; Türler, M.; Umana, G.; Valenziano, L.; Valiviita, J.; Van Tent, B.; Varis, J.; Vielva, P.; Villa, F.; Vittorio, N.; Wade, L. A.; Wandelt, B. D.; Watson, R.; Wilkinson, A.; Yvon, D.; Zacchei, A.; Zonca, A.

2014-11-01

We discuss the methods employed to photometrically calibrate the data acquired by the Low Frequency Instrument on Planck. Our calibration is based on a combination of the orbital dipole plus the solar dipole, caused respectively by the motion of the Planck spacecraft with respect to the Sun and by motion of the solar system with respect to the cosmic microwave background (CMB) rest frame. The latter provides a signal of a few mK with the same spectrum as the CMB anisotropies and is visible throughout the mission. In this data releasewe rely on the characterization of the solar dipole as measured by WMAP. We also present preliminary results (at 44 GHz only) on the study of the Orbital Dipole, which agree with the WMAP value of the solar system speed within our uncertainties. We compute the calibration constant for each radiometer roughly once per hour, in order to keep track of changes in the detectors' gain. Since non-idealities in the optical response of the beams proved to be important, we implemented a fast convolution algorithm which considers the full beam response in estimating the signal generated by the dipole. Moreover, in order to further reduce the impact of residual systematics due to sidelobes, we estimated time variations in the calibration constant of the 30 GHz radiometers (the ones with the largest sidelobes) using the signal of an internal reference load at 4 K instead of the CMB dipole. We have estimated the accuracy of the LFI calibration following two strategies: (1) we have run a set of simulations to assess the impact of statistical errors and systematic effects in the instrument and in the calibration procedure; and (2) we have performed a number of internal consistency checks on the data and on the brightness temperature of Jupiter. Errors in the calibration of this Planck/LFI data release are expected to be about 0.6% at 44 and 70 GHz, and 0.8% at 30 GHz. Both these preliminary results at low and high ℓ are consistent with WMAP results

36 CFR 1238.28 - What must agencies do when sending permanent microform records to a records storage facility?

Code of Federal Regulations, 2012 CFR

2012-07-01

... sending permanent microform records to a records storage facility? 1238.28 Section 1238.28 Parks, Forests... MANAGEMENT Storage, Use, and Disposition of Microform Records § 1238.28 What must agencies do when sending permanent microform records to a records storage facility? Agencies must: (a) Follow the procedures in part...

36 CFR 1238.28 - What must agencies do when sending permanent microform records to a records storage facility?

Code of Federal Regulations, 2014 CFR

2014-07-01

... sending permanent microform records to a records storage facility? 1238.28 Section 1238.28 Parks, Forests... MANAGEMENT Storage, Use, and Disposition of Microform Records § 1238.28 What must agencies do when sending permanent microform records to a records storage facility? Agencies must: (a) Follow the procedures in part...

36 CFR 1238.14 - What are the microfilming requirements for permanent and unscheduled records?

Code of Federal Regulations, 2014 CFR

2014-07-01

... accordance with ISO 18901 (incorporated by reference, see § 1238.5) and use the processing procedures in ANSI... § 1238.5). (2) Background density of images. Agencies must use the background ISO standard visual diffuse... transmission density. (i) Recommended visual diffuse transmission background densities for images of documents...

36 CFR 1238.14 - What are the microfilming requirements for permanent and unscheduled records?

Code of Federal Regulations, 2011 CFR

2011-07-01

... accordance with ISO 18901 (incorporated by reference, see § 1238.5) and use the processing procedures in ANSI... § 1238.5). (2) Background density of images. Agencies must use the background ISO standard visual diffuse... transmission density. (i) Recommended visual diffuse transmission background densities for images of documents...

36 CFR 1238.14 - What are the microfilming requirements for permanent and unscheduled records?

Code of Federal Regulations, 2012 CFR

2012-07-01

... accordance with ISO 18901 (incorporated by reference, see § 1238.5) and use the processing procedures in ANSI... § 1238.5). (2) Background density of images. Agencies must use the background ISO standard visual diffuse... transmission density. (i) Recommended visual diffuse transmission background densities for images of documents...

12 CFR 1238.4 - Methodologies and practices.

Code of Federal Regulations, 2014 CFR

2014-01-01

... conducting a stress test under § 1238.3, each regulated entity shall calculate how each of the following is affected during each quarter of the stress test planning horizon, for each scenario: (1) Potential losses, pre-provision net revenues, allowance for loan losses, and future pro forma capital positions over the...

Mutation in Torenia fournieri Lind. UFO homolog confers loss of TfLFY interaction and results in a petal to sepal transformation.

PubMed

Sasaki, Katsutomo; Yamaguchi, Hiroyasu; Aida, Ryutaro; Shikata, Masahito; Abe, Tomoko; Ohtsubo, Norihiro

2012-09-01

We identified a Torenia fournieri Lind. mutant (no. 252) that exhibited a sepaloid phenotype in which the second whorls were changed to sepal-like organs. This mutant had no stamens, and the floral organs consisted of sepals and carpels. Although the expression of a torenia class B MADS-box gene, GLOBOSA (TfGLO), was abolished in the 252 mutant, no mutation of TfGLO was found. Among torenia homologs such as APETALA1 (AP1), LEAFY (LFY), and UNUSUAL FLORAL ORGANS (UFO), which regulate expression of class B genes in Arabidopsis, only accumulation of the TfUFO transcript was diminished in the 252 mutant. Furthermore, a missense mutation was found in the coding region of the mutant TfUFO. Intact TfUFO complemented the mutant phenotype whereas mutated TfUFO did not; in addition, the transgenic phenotype of TfUFO-knockdown torenias coincided with the mutant phenotype. Yeast two-hybrid analysis revealed that the mutated TfUFO lost its ability to interact with TfLFY protein. In situ hybridization analysis indicated that the transcripts of TfUFO and TfLFY were partially accumulated in the same region. These results clearly demonstrate that the defect in TfUFO caused the sepaloid phenotype in the 252 mutant due to the loss of interaction with TfLFY. © 2012 The Authors. The Plant Journal © 2012 Blackwell Publishing Ltd.

36 CFR § 1238.28 - What must agencies do when sending permanent microform records to a records storage facility?

Code of Federal Regulations, 2013 CFR

2013-07-01

... sending permanent microform records to a records storage facility? § 1238.28 Section § 1238.28 Parks... RECORDS MANAGEMENT Storage, Use, and Disposition of Microform Records § 1238.28 What must agencies do when sending permanent microform records to a records storage facility? Agencies must: (a) Follow the...

36 CFR § 1238.14 - What are the microfilming requirements for permanent and unscheduled records?

Code of Federal Regulations, 2013 CFR

2013-07-01

... processing procedures in ANSI/AIIM MS1 and ANSI/AIIM MS23 (both incorporated by reference, see § 1238.5). (d... reference, see § 1238.5). (2) Background density of images. Agencies must use the background ISO standard... densities for images of documents are as follows: Classification Description of document Background density...

A systematic approach to the Planck LFI end-to-end test and its application to the DPC Level 1 pipeline

NASA Astrophysics Data System (ADS)

Frailis, M.; Maris, M.; Zacchei, A.; Morisset, N.; Rohlfs, R.; Meharga, M.; Binko, P.; Türler, M.; Galeotta, S.; Gasparo, F.; Franceschi, E.; Butler, R. C.; D'Arcangelo, O.; Fogliani, S.; Gregorio, A.; Lowe, S. R.; Maggio, G.; Malaspina, M.; Mandolesi, N.; Manzato, P.; Pasian, F.; Perrotta, F.; Sandri, M.; Terenzi, L.; Tomasi, M.; Zonca, A.

2009-12-01

The Level 1 of the Planck LFI Data Processing Centre (DPC) is devoted to the handling of the scientific and housekeeping telemetry. It is a critical component of the Planck ground segment which has to strictly commit to the project schedule to be ready for the launch and flight operations. In order to guarantee the quality necessary to achieve the objectives of the Planck mission, the design and development of the Level 1 software has followed the ESA Software Engineering Standards. A fundamental step in the software life cycle is the Verification and Validation of the software. The purpose of this work is to show an example of procedures, test development and analysis successfully applied to a key software project of an ESA mission. We present the end-to-end validation tests performed on the Level 1 of the LFI-DPC, by detailing the methods used and the results obtained. Different approaches have been used to test the scientific and housekeeping data processing. Scientific data processing has been tested by injecting signals with known properties directly into the acquisition electronics, in order to generate a test dataset of real telemetry data and reproduce as much as possible nominal conditions. For the HK telemetry processing, validation software have been developed to inject known parameter values into a set of real housekeeping packets and perform a comparison with the corresponding timelines generated by the Level 1. With the proposed validation and verification procedure, where the on-board and ground processing are viewed as a single pipeline, we demonstrated that the scientific and housekeeping processing of the Planck-LFI raw data is correct and meets the project requirements.

18 CFR 12.38 - Time for inspections and reports.

Code of Federal Regulations, 2010 CFR

2010-04-01

... PROJECT WORKS Inspection by Independent Consultant § 12.38 Time for inspections and reports. (a) General rule. After the initial inspection and report under this subpart for a project development, a new... before March 1, 1981 in compliance with the Commission's rules then in effect is deemed to fulfill the...

12 CFR 1238.7 - Publication of results by regulated entities.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 12 Banks and Banking 10 2014-01-01 2014-01-01 false Publication of results by regulated entities... TESTING OF REGULATED ENTITIES § 1238.7 Publication of results by regulated entities. (a) Public disclosure of results required for stress tests of regulated entities. The Enterprises must disclose publicly a...

Design and analysis of the cryoharness for Planck LFI

NASA Astrophysics Data System (ADS)

Leutenegger, Paolo H.; Bersanelli, Marco; Ferretti, Roberto; Prina, Mauro

2003-10-01

Planck is the third Medium-Sized Mission (M3) of ESA Horizon 2000 Scientific Programme. It is designed to image the anisotropies of the Cosmic Background Radiation Field over the whole sky, with unprecedented sensitivity and angular resolution. Planck carries two main experiments named HFI (High Frequency Instrument) and LFI (Low Frequency Instrument). The first is based on bolometers, the latter is an array of tuned radio receivers, based on High Electron Mobility Transistors (HEMTs) amplifier technology, and covering the frequency range from 30 to 70 GHz. The Front-End Electronics Modules (FEM"s) are cooled at 20K by a H2 sorption cooler. The high frequency signals (up to 70 GHz) are amplified, phase lagged and transported by means of waveguides to the warm back-end electronics at temperatures of the order of 300K. The 20 K cooling is achieved exploiting a two-stage cooling concept. The satellite is passively cooled to temperatures of the order of 60K using special designed radiators called V-grooves. An H2 sorption cooler constitutes the second active cooling stage, which allows focal plane temperatures of 20K, i.e. compatible with the tight noise requirements of the Low Noise Amplifiers (LNA"s). Each FEM needs 22 bias lines characterised by a high immunity to external noise and disturbances. The power required for each FEM ranges from 16 to 34mW, depending on the radiometer frequency. Due to the limited cooling power of the sorption cooler (about 2W), the heat transport through the harness and therefore the parasitics on the focal plane, shall be minimised. A total of 290 wires have to be routed from the warm electronics (300K) to the cold focal plane (20K), along a path of about 2200mm, transporting currents ranging from a few uA up to 240mA. The present paper analyses the thermal and electrical problems connected with the design of a suitable cryo-harness for the bias of the radiometers cryogenic front-end modules of LFI. Two possible approaches are proposed

36 CFR 1238.5 - What publications are incorporated by reference in this part?

Code of Federal Regulations, 2014 CFR

2014-07-01

... Stored Silver-Gelatin Microforms for Evidence of Deterioration, January 22, 1990, IBR approved for § 1238... Materials—Processed silver-gelatin type black-and-white films—Specifications for stability, February 15...

36 CFR 1238.5 - What publications are incorporated by reference in this part?

Code of Federal Regulations, 2011 CFR

2011-07-01

... Stored Silver-Gelatin Microforms for Evidence of Deterioration, January 22, 1990, IBR approved for § 1238... Materials—Processed silver-gelatin type black-and-white films—Specifications for stability, February 15...

36 CFR 1238.5 - What publications are incorporated by reference in this part?

Code of Federal Regulations, 2012 CFR

2012-07-01

... Stored Silver-Gelatin Microforms for Evidence of Deterioration, January 22, 1990, IBR approved for § 1238... Materials—Processed silver-gelatin type black-and-white films—Specifications for stability, February 15...

36 CFR 1238.1 - What is the scope of this part?

Code of Federal Regulations, 2014 CFR

2014-07-01

... ADMINISTRATION RECORDS MANAGEMENT MICROFORMS RECORDS MANAGEMENT General § 1238.1 What is the scope of this part? This part covers the standards and procedures for using micrographic technology in the management of... 36 Parks, Forests, and Public Property 3 2014-07-01 2014-07-01 false What is the scope of this...

36 CFR 1238.1 - What is the scope of this part?

Code of Federal Regulations, 2012 CFR

2012-07-01

... ADMINISTRATION RECORDS MANAGEMENT MICROFORMS RECORDS MANAGEMENT General § 1238.1 What is the scope of this part? This part covers the standards and procedures for using micrographic technology in the management of... 36 Parks, Forests, and Public Property 3 2012-07-01 2012-07-01 false What is the scope of this...

36 CFR 1238.1 - What is the scope of this part?

Code of Federal Regulations, 2010 CFR

2010-07-01

... ADMINISTRATION RECORDS MANAGEMENT MICROFORMS RECORDS MANAGEMENT General § 1238.1 What is the scope of this part? This part covers the standards and procedures for using micrographic technology in the management of... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false What is the scope of this...

Acquisition and diversification of tendrilled leaves in Bignonieae (Bignoniaceae) involved changes in expression patterns of SHOOTMERISTEMLESS (STM), LEAFY/FLORICAULA (LFY/FLO), and PHANTASTICA (PHAN).

PubMed

Sousa-Baena, Mariane Silveira; Lohmann, Lúcia G; Rossi, Magdalena; Sinha, Neelima R

2014-02-01

Leaves have undergone structural modifications over evolutionary time, and presently exist in many forms. For instance, in Fabaceae and Bignoniaceae, leaf parts can be modified into tendrils. Currently, no data are available on genic control of tendrilled leaf development outside Fabaceae. Here, we conducted a detailed study of three representatives of Bignonieae: Amphilophium buccinatorium, Dolichandra unguis-cati, and Bignonia callistegioides, bearing multifid, trifid, and simple-tendrilled leaves, respectively. We investigated the structure of their petioles, petiolules, leaflets, and tendrils through histological analyses. Additionally, the expression of SHOOTMERISTEMLESS (STM), PHANTASTICA (PHAN), and LEAFY/FLORICAULA (LFY/FLO) during leaf development was analyzed by in situ hybridizations. Tendrils share some anatomical similarities with leaflets, but not with other leaf parts. Transcripts of both STM and LFY/FLO were detected in leaf primordia, associated with regions from which leaflets and tendril branches originate. PHAN expression was found to be polarized in branched tendrils, but not in simple tendrils. In Bignonieae, tendrils are modified leaflets that, as a result of premature completion of development, become bladeless organs. Bignonieae leaves develop differently from those of peas, as both LFY/FLO and STM are expressed in developing leaves of Bignonieae. Moreover, PHAN is probably involved in tendril diversification in Bignonieae, as it has distinct expression patterns in different leaf types. © 2013 The Authors. New Phytologist © 2013 New Phytologist Trust.

36 CFR 1238.10 - What are the format standards for microfilming records?

Code of Federal Regulations, 2012 CFR

2012-07-01

... microfilming records: (a) Roll film—(1) Source documents. The formats described in ANSI/AIIM MS14 (incorporated by reference, see § 1238.5) must be used for microfilming source documents on 16mm and 35mm roll film... and format for meeting image quality requirements. When microfilming on 35mm film for aperture card...

36 CFR 1238.10 - What are the format standards for microfilming records?

Code of Federal Regulations, 2014 CFR

2014-07-01

... microfilming records: (a) Roll film—(1) Source documents. The formats described in ANSI/AIIM MS14 (incorporated by reference, see § 1238.5) must be used for microfilming source documents on 16mm and 35mm roll film... and format for meeting image quality requirements. When microfilming on 35mm film for aperture card...

36 CFR 1238.10 - What are the format standards for microfilming records?

Code of Federal Regulations, 2010 CFR

2010-07-01

... microfilming records: (a) Roll film—(1) Source documents. The formats described in ANSI/AIIM MS14 (incorporated by reference, see § 1238.5) must be used for microfilming source documents on 16mm and 35mm roll film... and format for meeting image quality requirements. When microfilming on 35mm film for aperture card...

36 CFR 1238.22 - What are the inspection requirements for permanent and unscheduled microform records?

Code of Federal Regulations, 2010 CFR

2010-07-01

... the microforms; (iv) A summary of any defects discovered, e.g., redox blemishes or base deformation... microform is deteriorating, the agency must make a silver duplicate in accordance with § 1238.14 to replace...

36 CFR 1238.22 - What are the inspection requirements for permanent and unscheduled microform records?

Code of Federal Regulations, 2011 CFR

2011-07-01

... the microforms; (iv) A summary of any defects discovered, e.g., redox blemishes or base deformation... microform is deteriorating, the agency must make a silver duplicate in accordance with § 1238.14 to replace...

36 CFR 1238.16 - What are the microfilming requirements for temporary records, duplicates, and user copies?

Code of Federal Regulations, 2014 CFR

2014-07-01

... noted in § 1238.3, and manufacturer's instructions for processing production, and maintenance of microform to ensure that the images are accessible and usable for the entire retention period of the records. ...

36 CFR 1238.16 - What are the microfilming requirements for temporary records, duplicates, and user copies?

Code of Federal Regulations, 2012 CFR

2012-07-01

... noted in § 1238.3, and manufacturer's instructions for processing production, and maintenance of microform to ensure that the images are accessible and usable for the entire retention period of the records. ...

36 CFR 1238.16 - What are the microfilming requirements for temporary records, duplicates, and user copies?

Code of Federal Regulations, 2011 CFR

2011-07-01

... noted in § 1238.3, and manufacturer's instructions for processing production, and maintenance of microform to ensure that the images are accessible and usable for the entire retention period of the records. ...

36 CFR 1238.16 - What are the microfilming requirements for temporary records, duplicates, and user copies?

Code of Federal Regulations, 2010 CFR

2010-07-01

... noted in § 1238.3, and manufacturer's instructions for processing production, and maintenance of microform to ensure that the images are accessible and usable for the entire retention period of the records. ...

36 CFR § 1238.10 - What are the format standards for microfilming records?

Code of Federal Regulations, 2013 CFR

2013-07-01

... microfilming records: (a) Roll film—(1) Source documents. The formats described in ANSI/AIIM MS14 (incorporated by reference, see § 1238.5) must be used for microfilming source documents on 16mm and 35mm roll film... and format for meeting image quality requirements. When microfilming on 35mm film for aperture card...

36 CFR § 1238.16 - What are the microfilming requirements for temporary records, duplicates, and user copies?

Code of Federal Regulations, 2013 CFR

2013-07-01

... noted in § 1238.3, and manufacturer's instructions for processing production, and maintenance of microform to ensure that the images are accessible and usable for the entire retention period of the records. ...

19 CFR 123.8 - Permit or special license to unlade or lade a vessel or vehicle.

Code of Federal Regulations, 2010 CFR

2010-04-01

... the application and permission to unlade be on Customs Form 3171. (2) Special license to unlade or lade at night, on a Sunday or holiday. Application for permission to unlade passengers or merchandise... § 123.8 Permit or special license to unlade or lade a vessel or vehicle. (a) Permission to unlade or...

5. INTERIOR VIEW SHOWING RAFTER CONSTRUCTION. SOUTHERN EXTENSION AT LEFT. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. INTERIOR VIEW SHOWING RAFTER CONSTRUCTION. SOUTHERN EXTENSION AT LEFT. - Chollas Heights Naval Radio Transmitting Facility, Operational Storage Building, 6410 Zero Road, San Diego, San Diego County, CA

36 CFR 1238.30 - What must agencies do when transferring permanent microform records to the National Archives of...

Code of Federal Regulations, 2011 CFR

2011-07-01

... specified in § 1232.14(c) of this subchapter. (c) Transfer the silver gelatin original (or duplicate silver gelatin microform created in accordance with § 1238.14) plus one microform copy. (d) Ensure that the... separately from the silver gelatin original or silver duplicate microform copy and clearly label them as non...

36 CFR 1238.30 - What must agencies do when transferring permanent microform records to the National Archives of...

Code of Federal Regulations, 2014 CFR

2014-07-01

... specified in § 1232.14(c) of this subchapter. (c) Transfer the silver gelatin original (or duplicate silver gelatin microform created in accordance with § 1238.14) plus one microform copy. (d) Ensure that the... separately from the silver gelatin original or silver duplicate microform copy and clearly label them as non...

36 CFR 1238.30 - What must agencies do when transferring permanent microform records to the National Archives of...

Code of Federal Regulations, 2012 CFR

2012-07-01

... specified in § 1232.14(c) of this subchapter. (c) Transfer the silver gelatin original (or duplicate silver gelatin microform created in accordance with § 1238.14) plus one microform copy. (d) Ensure that the... separately from the silver gelatin original or silver duplicate microform copy and clearly label them as non...

36 CFR 1238.30 - What must agencies do when transferring permanent microform records to the National Archives of...

Code of Federal Regulations, 2010 CFR

2010-07-01

... specified in § 1232.14(c) of this subchapter. (c) Transfer the silver gelatin original (or duplicate silver gelatin microform created in accordance with § 1238.14) plus one microform copy. (d) Ensure that the... separately from the silver gelatin original or silver duplicate microform copy and clearly label them as non...

3. OBLIQUE VIEW LOOKING NORTHWEST SHOWING GARAGE EXTENSION WITH DOORS. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. OBLIQUE VIEW LOOKING NORTHWEST SHOWING GARAGE EXTENSION WITH DOORS. VIEW FROM BUILDING 15. - Chollas Heights Naval Radio Transmitting Facility, Public Works Shop, 6410 Zero Road, San Diego, San Diego County, CA

12 CFR 1238.5 - Required report to FHFA and the FRB of stress test results and related information.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 12 Banks and Banking 10 2014-01-01 2014-01-01 false Required report to FHFA and the FRB of stress... AGENCY ENTITY REGULATIONS STRESS TESTING OF REGULATED ENTITIES § 1238.5 Required report to FHFA and the FRB of stress test results and related information. (a) Report required for stress tests. On or before...

22. FANTAIL DECK, SHOWING DETAIL OF DECK EXTENSION AND EXTERIOR ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

22. FANTAIL DECK, SHOWING DETAIL OF DECK EXTENSION AND EXTERIOR LOCKING MECHANISM ON HATCH DOOR TO CREW'S BERTHING. - U.S. Coast Guard Cutter WHITE HEATH, USGS Integrated Support Command Boston, 427 Commercial Street, Boston, Suffolk County, MA

36 CFR § 1238.30 - What must agencies do when transferring permanent microform records to the National Archives of...

Code of Federal Regulations, 2013 CFR

2013-07-01

... information specified in § 1232.14(c) of this subchapter. (c) Transfer the silver gelatin original (or duplicate silver gelatin microform created in accordance with § 1238.14) plus one microform copy. (d) Ensure... non-silver copies separately from the silver gelatin original or silver duplicate microform copy and...

21. FANTAIL DECK, SHOWING DETAIL OF DECK EXTENSION AND EXTERIOR ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

21. FANTAIL DECK, SHOWING DETAIL OF DECK EXTENSION AND EXTERIOR LOCKING MECHANISM ON HATCH DOOR TO CREW'S BERTHING. - U.S. Coast Guard Cutter WHITE LUPINE, U.S. Coast Guard Station Rockland, east end of Tillson Avenue, Rockland, Knox County, ME

Overexpression of LEAFY in apple leads to a columnar phenotype with shorter internodes.

PubMed

Flachowsky, Henryk; Hättasch, Conny; Höfer, Monika; Peil, Andreas; Hanke, Magda-Viola

2010-01-01

To break the juvenile stage of apple (Malus x domestica Borkh.) we transferred the LFY gene of Arabidopsis into the genome of the apple cv. 'Pinova'. A total of five transgenic clones constitutively overexpressing the LFY gene were obtained. Approximately, 20 shoots of each clone were rooted and transferred to the glasshouse. No flowers were obtained on transgenic plants during the first 2 years of cultivation. Evaluation of the expression of possible LFY targets revealed that no transcripts could be detected for MdAP1-1 and MdAP1-2. MdTFL1 was unaffected. Based on the absence of the LFY core-binding sequence within promoter sequences of MdAP1-1 and MdAP1-2, it was concluded that LFY was not able to induce these genes. The LFY genes of apple were unaffected in transgenic plants and sequence alignments of the C-terminal amino acid sequence showed a high conservation of these proteins. A change in binding ability to DNA can therefore be excluded. Instead of early flowering, the transgenic plants showed an altered phenotype, which is similar to the columnar phenotype of the 'McIntosh Wijcik' mutant of apple. The transgenic plants showed shortened internodes and a significantly reduced length of the regrowing shoot. A negative correlation was observed between the length of the regrowing shoot and the LFY mRNA transcript level. Furthermore, the LFY transgenic apple plants showed an increased shoot diameter at node 20, which was positively correlated with the LFY mRNA transcript level. Based on our results, we assume an alternative role of LFY in apple.

Molecular cloning and characterization of a gene regulating flowering time from Alfalfa (Medicago sativa L.).

PubMed

Zhang, Tiejun; Chao, Yuehui; Kang, Junmei; Ding, Wang; Yang, Qingchuan

2013-07-01

Genes that regulate flowering time play crucial roles in plant development and biomass formation. Based on the cDNA sequence of Medicago truncatula (accession no. AY690425), the LFY gene of alfalfa was cloned. Sequence similarity analysis revealed high homology with FLO/LFY family genes of other plants. When fused to the green fluorescent protein, MsLFY protein was localized in the nucleus of onion (Allium cepa L.) epidermal cells. The RT-qPCR analysis of MsLFY expression patterns showed that the expression of MsLFY gene was at a low level in roots, stems, leaves and pods, and the expression level in floral buds was the highest. The expression of MsLFY was induced by GA3 and long photoperiod. Plant expression vector was constructed and transformed into Arabidopsis by the agrobacterium-mediated methods. PCR amplification with the transgenic Arabidopsis genome DNA indicated that MsLFY gene had integrated in Arabidopsis genome. Overexpression of MsLFY specifically caused early flowering under long day conditions compared with non-transgenic plants. These results indicated MsLFY played roles in promoting flowering time.

Rapid detection of methicillin-resistant Staphylococcus aureus in pork using a nucleic acid-based lateral flow immunoassay.

PubMed

Zhang, Hongwei; Ma, Luyao; Ma, Lina; Hua, Marti Z; Wang, Shuo; Lu, Xiaonan

2017-02-21

Methicillin-resistant Staphylococcus aureus (MRSA) is considered as one of the leading causes of food poisonings worldwide. Due to the high prevalence and extensive challenges in clinical treatment, a rapid and accurate detection method is required to differentiate MRSA from other S. aureus isolated from foods. Since the methicillin resistance of S. aureus is due to the acquisition of the mecA gene from staphylococcal chromosome cassette, the presence of the mecA gene is interpreted as a marker for the identification of MRSA. In this study, a low-cost lateral flow immunoassay (LFI) strip was used to detect the mecA amplicons subsequent to polymerase chain reaction (PCR). The specificity of this PCR-LFI assay was tested between MRSA and methicillin-susceptive S. aureus. Both the test line and control line were shown up on the LFI strip for MRSA, whereas only the control line developed for methicillin-susceptive S. aureus. The detection limit of PCR-LFI assay was 20fg for genomic DNA (100 times more sensitive than gel electrophoresis) and 2×10 0 CFU per 100g of pork products after enrichment at 37°C for 48h. The total detection time of using LFI was 3min, which was faster than the conventional electrophoresis (~45min). With the performance of PCR-LFI, 7 out of 42 S. aureus isolates were identified to be MRSA from imported pork products, which was consistent to the standardized minimum inhibitory concentration assay. This mecA-based PCR-LFI strip can be used for rapid and accurate detection of MRSA isolated from commercial pork products. Copyright © 2016. Published by Elsevier B.V.

Evolutionary Co-Option of Floral Meristem Identity Genes for Patterning of the Flower-Like Asteraceae Inflorescence1

PubMed Central

Broholm, Suvi K.; Tähtiharju, Sari

2016-01-01

The evolutionary success of Asteraceae, the largest family of flowering plants, has been attributed to the unique inflorescence architecture of the family, which superficially resembles an individual flower. Here, we show that Asteraceae inflorescences (flower heads, or capitula) resemble solitary flowers not only morphologically but also at the molecular level. By conducting functional analyses for orthologs of the flower meristem identity genes LEAFY (LFY) and UNUSUAL FLORAL ORGANS (UFO) in Gerbera hybrida, we show that GhUFO is the master regulator of flower meristem identity, while GhLFY has evolved a novel, homeotic function during the evolution of head-like inflorescences. Resembling LFY expression in a single flower meristem, uniform expression of GhLFY in the inflorescence meristem defines the capitulum as a determinate structure that can assume floral fate upon ectopic GhUFO expression. We also show that GhLFY uniquely regulates the ontogeny of outer, expanded ray flowers but not inner, compact disc flowers, indicating that the distinction of different flower types in Asteraceae is connected with their independent evolutionary origins from separate branching systems. PMID:27382139

Genomic identification of direct target genes of LEAFY

PubMed Central

William, Dilusha A.; Su, Yanhui; Smith, Michael R.; Lu, Meina; Baldwin, Don A.; Wagner, Doris

2004-01-01

The switch from vegetative to reproductive development in plants necessitates a switch in the developmental program of the descendents of the stem cells in the shoot apical meristem. Genetic and molecular investigations have demonstrated that the plant-specific transcription factor and meristem identity regulator LEAFY (LFY) controls this developmental transition by inducing expression of a second transcription factor, APETALA1, and by regulating the expression of additional, as yet unknown, genes. Here we show that the additional LFY targets include the APETALA1-related factor, CAULI-FLOWER, as well as three transcription factors and two putative signal transduction pathway components. These genes are up-regulated by LFY even when protein synthesis is inhibited and, hence, appear to be direct targets of LFY. Supporting this conclusion, cis-regulatory regions upstream of these genes are bound by LFY in vivo. The newly identified LFY targets likely initiate the transcriptional changes that are required for the switch from vegetative to reproductive development in Arabidopsis. PMID:14736918

Transcription Factor Interplay between LEAFY and APETALA1/CAULIFLOWER during Floral Initiation1

PubMed Central

Zheng, Beibei; Kwaśniewska, Kamila; Thomson, Bennett

2017-01-01

The transcription factors LEAFY (LFY) and APETALA1 (AP1), together with the AP1 paralog CAULIFLOWER (CAL), control the onset of flower development in a partially redundant manner. This redundancy is thought to be mediated, at least in part, through the regulation of a shared set of target genes. However, whether these genes are independently or cooperatively regulated by LFY and AP1/CAL is currently unknown. To better understand the regulatory relationship between LFY and AP1/CAL and to obtain deeper insights into the control of floral initiation, we monitored the activity of LFY in the absence of AP1/CAL function. We found that the regulation of several known LFY target genes is unaffected by AP1/CAL perturbation, while others appear to require AP1/CAL activity. Furthermore, we obtained evidence that LFY and AP1/CAL control the expression of some genes in an antagonistic manner. Notably, these include key regulators of floral initiation such as TERMINAL FLOWER1 (TFL1), which had been previously reported to be directly repressed by both LFY and AP1. We show here that TFL1 expression is suppressed by AP1 but promoted by LFY. We further demonstrate that LFY has an inhibitory effect on flower formation in the absence of AP1/CAL activity. We propose that LFY and AP1/CAL act as part of an incoherent feed-forward loop, a network motif where two interconnected pathways or transcription factors act in opposite directions on a target gene, to control the establishment of a stable developmental program for the formation of flowers. PMID:28385730

Transcription Factor Interplay between LEAFY and APETALA1/CAULIFLOWER during Floral Initiation.

PubMed

Goslin, Kevin; Zheng, Beibei; Serrano-Mislata, Antonio; Rae, Liina; Ryan, Patrick T; Kwaśniewska, Kamila; Thomson, Bennett; Ó'Maoiléidigh, Diarmuid S; Madueño, Francisco; Wellmer, Frank; Graciet, Emmanuelle

2017-06-01

The transcription factors LEAFY (LFY) and APETALA1 (AP1), together with the AP1 paralog CAULIFLOWER (CAL), control the onset of flower development in a partially redundant manner. This redundancy is thought to be mediated, at least in part, through the regulation of a shared set of target genes. However, whether these genes are independently or cooperatively regulated by LFY and AP1/CAL is currently unknown. To better understand the regulatory relationship between LFY and AP1/CAL and to obtain deeper insights into the control of floral initiation, we monitored the activity of LFY in the absence of AP1/CAL function. We found that the regulation of several known LFY target genes is unaffected by AP1/CAL perturbation, while others appear to require AP1/CAL activity. Furthermore, we obtained evidence that LFY and AP1/CAL control the expression of some genes in an antagonistic manner. Notably, these include key regulators of floral initiation such as TERMINAL FLOWER1 ( TFL1 ), which had been previously reported to be directly repressed by both LFY and AP1. We show here that TFL1 expression is suppressed by AP1 but promoted by LFY. We further demonstrate that LFY has an inhibitory effect on flower formation in the absence of AP1/CAL activity. We propose that LFY and AP1/CAL act as part of an incoherent feed-forward loop, a network motif where two interconnected pathways or transcription factors act in opposite directions on a target gene, to control the establishment of a stable developmental program for the formation of flowers. © 2017 American Society of Plant Biologists. All Rights Reserved.

An Arabidopsis F-box protein acts as a transcriptional co-factor to regulate floral development.

PubMed

Chae, Eunyoung; Tan, Queenie K-G; Hill, Theresa A; Irish, Vivian F

2008-04-01

Plants flower in response to both environmental and endogenous signals. The Arabidopsis LEAFY (LFY) transcription factor is crucial in integrating these signals, and acts in part by activating the expression of multiple floral homeotic genes. LFY-dependent activation of the homeotic APETALA3 (AP3) gene requires the activity of UNUSUAL FLORAL ORGANS (UFO), an F-box component of an SCF ubiquitin ligase, yet how this regulation is effected has remained unclear. Here, we show that UFO physically interacts with LFY both in vitro and in vivo, and this interaction is necessary to recruit UFO to the AP3 promoter. Furthermore, a transcriptional repressor domain fused to UFO reduces endogenous LFY activity in plants, supporting the idea that UFO acts as part of a transcriptional complex at the AP3 promoter. Moreover, chemical or genetic disruption of proteasome activity compromises LFY-dependent AP3 activation, indicating that protein degradation is required to promote LFY activity. These results define an unexpected role for an F-box protein in functioning as a DNA-associated transcriptional co-factor in regulating floral homeotic gene expression. These results suggest a novel mechanism for promoting flower development via protein degradation and concomitant activation of the LFY transcription factor. This mechanism may be widely conserved, as homologs of UFO and LFY have been identified in a wide array of plant species.

Evolutionary Co-Option of Floral Meristem Identity Genes for Patterning of the Flower-Like Asteraceae Inflorescence.

PubMed

Zhao, Yafei; Zhang, Teng; Broholm, Suvi K; Tähtiharju, Sari; Mouhu, Katriina; Albert, Victor A; Teeri, Teemu H; Elomaa, Paula

2016-09-01

The evolutionary success of Asteraceae, the largest family of flowering plants, has been attributed to the unique inflorescence architecture of the family, which superficially resembles an individual flower. Here, we show that Asteraceae inflorescences (flower heads, or capitula) resemble solitary flowers not only morphologically but also at the molecular level. By conducting functional analyses for orthologs of the flower meristem identity genes LEAFY (LFY) and UNUSUAL FLORAL ORGANS (UFO) in Gerbera hybrida, we show that GhUFO is the master regulator of flower meristem identity, while GhLFY has evolved a novel, homeotic function during the evolution of head-like inflorescences. Resembling LFY expression in a single flower meristem, uniform expression of GhLFY in the inflorescence meristem defines the capitulum as a determinate structure that can assume floral fate upon ectopic GhUFO expression. We also show that GhLFY uniquely regulates the ontogeny of outer, expanded ray flowers but not inner, compact disc flowers, indicating that the distinction of different flower types in Asteraceae is connected with their independent evolutionary origins from separate branching systems. © 2016 American Society of Plant Biologists. All rights reserved.

Functional characterization of a novel Brassica LEAFY homolog from Indian mustard: Expression pattern and gain-of-function studies.

PubMed

Dhakate, Priyanka; Tyagi, Shikha; Singh, Anupama; Singh, Anandita

2017-05-01

LEAFY plays a central role in regulation of flowering time and floral meristem identity in plants. Unfortunately, LFY function remains uncharacterized in agronomicaly important Brassicas. Herein, we illustrate fine-mapping of expression domains of LFY in 15 cultivars of 6 Brassica species and describe gain-of-function phenotypes in Arabidopsis and Brassica. We depict early flowering and altered fatty-acid composition in transgenic seed. The cDNA encoding BjuLFY (417aa) shared only 85% identity with reported homolog of B.juncea implying distinctness. Quantitative RT-PCR based coarse expression mapping of BjuLFY in tissue samples representing 3 time points at specific days after sowing (DAS), pre-flowering (30 DAS), flowering (75 DAS) and post-flowering (110 DAS), depicted an intense pulse of BjuLFY expression restricted to primary floral buds (75 DAS) which subsided in secondary floral buds (110 DAS); expression in root samples was also recorded implying neo-functionalization. Fine-mapping of expression during flowering confirmed tightly regulated LFY expression during early stages of bud development in 15 cultivars of 6 Brassica species implying functional conservation. Ectopic expression of BjuLFY in A. thaliana and B. juncea caused floral meristem defects and precocious flowering. B. juncea transgenics (T 1 ) over-expressing BjuLFY flowered 20days earlier produced normal flowers. GC-MS analysis of mature seed from Brassica transgenics showed an altered fatty-acid profile suggestive of seed maturation occurring at lower temperatures vis-à-vis control. Our findings implicate BjuLFY as a regulator of flowering in B. juncea and suggest its application in developing climate resilient crops. Copyright © 2017 Elsevier B.V. All rights reserved.

Switching on Flowers: Transient LEAFY Induction Reveals Novel Aspects of the Regulation of Reproductive Development in Arabidopsis

PubMed Central

Wagner, Doris; Meyerowitz, Elliot M.

2011-01-01

Developmental fate decisions in cell populations fundamentally depend on at least two parameters: a signal that is perceived by the cell and the intrinsic ability of the cell to respond to the signal. The same regulatory logic holds for phase transitions in the life cycle of an organism, for example the switch to reproductive development in flowering plants. Here we have tested the response of the monocarpic plant species Arabidopsis thaliana to a signal that directs flower formation, the plant-specific transcription factor LEAFY (LFY). Using transient steroid-dependent LEAFY (LFY) activation in lfy null mutant Arabidopsis plants, we show that the plant’s competence to respond to the LFY signal changes during development. Very early in the life cycle, the plant is not competent to respond to the signal. Subsequently, transient LFY activation can direct primordia at the flanks of the shoot apical meristem to adopt a floral fate. Finally, the plants acquire competence to initiate the flower-patterning program in response to transient LFY activation. Similar to a perennial life strategy, we did not observe reprogramming of all primordia after perception of the transient signal, instead only a small number of meristems responded, followed by reversion to the prior developmental program. The ability to initiate flower formation and to direct flower patterning in response to transient LFY upregulation was dependent on the known direct LFY target APETALA1 (AP1). Prolonged LFY or activation could alter the developmental gradient and bypass the requirement for AP1. Prolonged high AP1 levels, in turn, can also alter the plants’ competence. Our findings shed light on how plants can fine-tune important phase transitions and developmental responses. PMID:22639600

An ortholog of LEAFY in Jatropha curcas regulates flowering time and floral organ development.

PubMed

Tang, Mingyong; Tao, Yan-Bin; Fu, Qiantang; Song, Yaling; Niu, Longjian; Xu, Zeng-Fu

2016-11-21

Jatropha curcas seeds are an excellent biofuel feedstock, but seed yields of Jatropha are limited by its poor flowering and fruiting ability. Thus, identifying genes controlling flowering is critical for genetic improvement of seed yield. We isolated the JcLFY, a Jatropha ortholog of Arabidopsis thaliana LEAFY (LFY), and identified JcLFY function by overexpressing it in Arabidopsis and Jatropha. JcLFY is expressed in Jatropha inflorescence buds, flower buds, and carpels, with highest expression in the early developmental stage of flower buds. JcLFY overexpression induced early flowering, solitary flowers, and terminal flowers in Arabidopsis, and also rescued the delayed flowering phenotype of lfy-15, a LFY loss-of-function Arabidopsis mutant. Microarray and qPCR analysis revealed several flower identity and flower organ development genes were upregulated in JcLFY-overexpressing Arabidopsis. JcLFY overexpression in Jatropha also induced early flowering. Significant changes in inflorescence structure, floral organs, and fruit shape occurred in JcLFY co-suppressed plants in which expression of several flower identity and floral organ development genes were changed. This suggests JcLFY is involved in regulating flower identity, floral organ patterns, and fruit shape, although JcLFY function in Jatropha floral meristem determination is not as strong as that of Arabidopsis.

An ortholog of LEAFY in Jatropha curcas regulates flowering time and floral organ development

PubMed Central

Tang, Mingyong; Tao, Yan-Bin; Fu, Qiantang; Song, Yaling; Niu, Longjian; Xu, Zeng-Fu

2016-01-01

Jatropha curcas seeds are an excellent biofuel feedstock, but seed yields of Jatropha are limited by its poor flowering and fruiting ability. Thus, identifying genes controlling flowering is critical for genetic improvement of seed yield. We isolated the JcLFY, a Jatropha ortholog of Arabidopsis thaliana LEAFY (LFY), and identified JcLFY function by overexpressing it in Arabidopsis and Jatropha. JcLFY is expressed in Jatropha inflorescence buds, flower buds, and carpels, with highest expression in the early developmental stage of flower buds. JcLFY overexpression induced early flowering, solitary flowers, and terminal flowers in Arabidopsis, and also rescued the delayed flowering phenotype of lfy-15, a LFY loss-of-function Arabidopsis mutant. Microarray and qPCR analysis revealed several flower identity and flower organ development genes were upregulated in JcLFY-overexpressing Arabidopsis. JcLFY overexpression in Jatropha also induced early flowering. Significant changes in inflorescence structure, floral organs, and fruit shape occurred in JcLFY co-suppressed plants in which expression of several flower identity and floral organ development genes were changed. This suggests JcLFY is involved in regulating flower identity, floral organ patterns, and fruit shape, although JcLFY function in Jatropha floral meristem determination is not as strong as that of Arabidopsis. PMID:27869146

[Sequence analysis of LEAFY homologous gene from Dendrobium moniliforme and application for identification of medicinal Dendrobium].

PubMed

Xing, Wen-Rui; Hou, Bei-Wei; Guan, Jing-Jiao; Luo, Jing; Ding, Xiao-Yu

2013-04-01

The LEAFY (LFY) homologous gene of Dendrobium moniliforme (L.) Sw. was cloned by new primers which were designed based on the conservative region of known sequences of orchid LEAFY gene. Partial LFY homologous gene was cloned by common PCR, then we got the complete LFY homologous gene Den LFY by Tail-PCR. The complete sequence of DenLFY gene was 3 575 bp which contained three exons and two introns. Using BLAST method, comparison analysis among the exon of LFY homologous gene indicted that the DenLFY gene had high identity with orchids LFY homologous, including the related fragment of PhalLFY (84%) in Phalaenopsis hybrid cultivar, LFY homologous gene in Oncidium (90%) and in other orchid (over 80%). Using MP analysis, Dendrobium is found to be the sister to Oncidium and Phalaenopsis. Homologous analysis demonstrated that the C-terminal amino acids were highly conserved. When the exons and introns were separately considered, exons and the sequence of amino acid were good markers for the function research of DenLFY gene. The second intron can be used in authentication research of Dendrobium based on the length polymorphism between Dendrobium moniliforme and Dendrobium officinale.

Optical feedback effects on terahertz quantum cascade lasers: modelling and applications

NASA Astrophysics Data System (ADS)

Rakić, Aleksandar D.; Lim, Yah Leng; Taimre, Thomas; Agnew, Gary; Qi, Xiaoqiong; Bertling, Karl; Han, She; Wilson, Stephen J.; Kundu, Iman; Grier, Andrew; Ikonić, Zoran; Valavanis, Alexander; Demić, Aleksandar; Keeley, James; Li, Lianhe H.; Linfield, Edmund H.; Davies, A. Giles; Harrison, Paul; Ferguson, Blake; Walker, Graeme; Prow, Tarl; Indjin, Dragan; Soyer, H. Peter

2016-11-01

Terahertz (THz) quantum cascade lasers (QCLs) are compact sources of radiation in the 1-5 THz range with significant potential for applications in sensing and imaging. Laser feedback interferometry (LFI) with THz QCLs is a technique utilizing the sensitivity of the QCL to the radiation reflected back into the laser cavity from an external target. We will discuss modelling techniques and explore the applications of LFI in biological tissue imaging and will show that the confocal nature of the QCL in LFI systems, with their innate capacity for depth sectioning, makes them suitable for skin diagnostics with the well-known advantages of more conventional confocal microscopes. A demonstration of discrimination of neoplasia from healthy tissue using a THz, LFI-based system in the context of melanoma is presented using a transgenic mouse model.

Functional Characterization of PhapLEAFY, a FLORICAULA/LEAFY Ortholog in Phalaenopsis aphrodite.

PubMed

Jang, Seonghoe

2015-11-01

The plant-specific transcription factor LEAFY (LFY) is considered to be a master regulator of flower development in the model plant, Arabidopsis. This protein plays a dual role in plant growth, integrating signals from the floral inductive pathways and acting as a floral meristem identity gene by activating genes for floral organ development. Although LFY occupies an important position in flower development, the functional divergence of LFY homologs has been demonstrated in several plants including monocots and gymnosperms. In particular, the functional roles of LFY genes from orchid species such as Phalaenopsis that contain unique floral morphologies with distinct expression patterns of floral organ identity genes remain elusive. Here, PhapLFY, an ortholog of Arabidopsis LFY from Phalaenopsis aphrodite subsp. formosana, a Taiwanese native monopodial orchid, was isolated and characterized through analyses of expression and protein activity. PhapLFY transcripts accumulated in the floral primordia of developing inflorescences, and the PhapLFY protein had transcriptional autoactivation activity forming as a homodimer. Furthermore, PhapLFY rescues the aberrant floral phenotypes of Arabidopsis lfy mutants. Overexpression of PhapLFY alone or together with PhapFT1, a P. aphrodite subsp. formosana homolog of Arabidopsis FLOWERING LOCUS T (FT) in rice, caused precocious heading. Consistently, a higher Chl content in the sepals and morphological changes in epidermal cells were observed in the floral organs of PhapLFY knock-down orchids generated by virus-induced gene silencing. Taken together, these results suggest that PhapLFY is functionally distinct from RICE FLORICAULA/LEAFY (RFL) but similar to Arabidopsis LFY based on phenotypes of our transgenic Arabidopsis and rice plants. © The Author 2015. Published by Oxford University Press on behalf of Japanese Society of Plant Physiologists. All rights reserved. For permissions, please email: journals.permissions@oup.com.

Overexpression of the cucumber LEAFY homolog CFL and hormone treatments alter flower development in gloxinia (Sinningia speciosa).

PubMed

Zhang, Ming-Zhe; Ye, Dan; Wang, Li-Lin; Pang, Ji-Liang; Zhang, Yu-Hong; Zheng, Ke; Bian, Hong-Wu; Han, Ning; Pan, Jian-Wei; Wang, Jun-Hui; Zhu, Mu-Yuan

2008-07-01

Leafy (LFY) and LFY-like genes control the initiation of floral meristems and regulate MADS-box genes in higher plants. The Cucumber-FLO-LFY (CFL) gene, a LFY homolog in Cucumis sativus L. is expressed in the primordia, floral primordia, and each whirl of floral organs during the early stage of flower development. In this study, functions of CFL in flower development were investigated by overexpressing the CFL gene in gloxinia (Sinningia speciosa). Our results show that constitutive CFL overexpression significantly promote early flowering without gibberellin (GA(3)) supplement, suggesting that CFL can serve functionally as a LFY homolog in gloxinia. Moreover, GA(3) and abscisic acid (ABA) treatments could modulate the expression of MADS-box genes in opposite directions. GA(3) resembles the overexpression of CFL in the expression of MADS-box genes and the regeneration of floral buds, but ABA inhibits the expression of MADS-box genes and flower development. These results suggest that CFL and downstream MADS-box genes involved in flower development are regulated by GA(3) and ABA.

LitR of Vibrio salmonicida Is a Salinity-Sensitive Quorum-Sensing Regulator of Phenotypes Involved in Host Interactions and Virulence

PubMed Central

Bjelland, Ane Mohn; Sørum, Henning; Tegegne, Daget Ayana; Winther-Larsen, Hanne C.; Willassen, Nils Peder

2012-01-01

Vibrio (Aliivibrio) salmonicida is the causal agent of cold-water vibriosis, a fatal bacterial septicemia primarily of farmed salmonid fish. The molecular mechanisms of invasion, colonization, and growth of V. salmonicida in the host are still largely unknown, and few virulence factors have been identified. Quorum sensing (QS) is a cell-to-cell communication system known to regulate virulence and other activities in several bacterial species. The genome of V. salmonicida LFI1238 encodes products presumably involved in several QS systems. In this study, the gene encoding LitR, a homolog of the master regulator of QS in V. fischeri, was deleted. Compared to the parental strain, the litR mutant showed increased motility, adhesion, cell-to-cell aggregation, and biofilm formation. Furthermore, the litR mutant produced less cryptic bioluminescence, whereas production of acylhomoserine lactones was unaffected. Our results also indicate a salinity-sensitive regulation of LitR. Finally, reduced mortality was observed in Atlantic salmon infected with the litR mutant, implying that the fish were more susceptible to infection with the wild type than with the mutant strain. We hypothesize that LitR inhibits biofilm formation and favors planktonic growth, with the latter being more adapted for pathogenesis in the fish host. PMID:22371373

A LEAFY co-regulator encoded by UNUSUAL FLORAL ORGANS.

PubMed

Lee, I; Wolfe, D S; Nilsson, O; Weigel, D

1997-02-01

. Development of petals and stamens in Arabidopsis flowers requires the function of the organ-identity gene APETALA3 (AP3), whose RNA is expressed specifically in petal and stamen primordia. AP3 expression is positively regulated by the meristem-identity gene LEAFY (LFY), which is expressed ubiquitously in young flowers. It is unknown how the transition from ubiquitous expression of LFY to region-specific expression of AP3 is made. It has previously been proposed for Antirrhinum that another gene, FIMBRIATA (FIM), mediates between the LFY and AP3 orthologs, with the three genes acting in a simple regulatory hierarchy. FIM is activated later than the LFY ortholog, and its expression is more restricted than that of the LFY ortholog. . We have tested whether the model proposed for Antirrhinum applies to Arabidopsis, by creating transgenic plants in which the FIM ortholog UNUSUAL FLORAL ORGANS (UFO) was expressed constitutively from the promoter of the cauliflower mosaic virus 35S gene. In 35S::UFO flowers, AP3 was expressed precociously and ectopically, confirming that UFO is an upstream regulator of AP3. However, 35S::UFO could not restore petal and stamen development in lfy mutants, indicating that UFO can only function in the presence of LFY activity. The failure of 35S::UFO to rescue lfy mutants is consistent with our observation that UFO expression levels are not markedly changed in lfy mutants. . We conclude that UFO is not a simple mediator between meristem- and organ-identity genes, but is likely to be a partially dispensable co-regulator that acts together with LFY. The interplay between LFY and UFO provides a paradigm for how a global regulator such as LFY activates selected target genes only in restricted regions within its expression domain.

Interdependence of torque, joint angle, angular velocity and muscle action during human multi-joint leg extension.

PubMed

Hahn, Daniel; Herzog, Walter; Schwirtz, Ansgar

2014-08-01

Force and torque production of human muscles depends upon their lengths and contraction velocity. However, these factors are widely assumed to be independent of each other and the few studies that dealt with interactions of torque, angle and angular velocity are based on isolated single-joint movements. Thus, the purpose of this study was to determine force/torque-angle and force/torque-angular velocity properties for multi-joint leg extensions. Human leg extension was investigated (n = 18) on a motor-driven leg press dynamometer while measuring external reaction forces at the feet. Extensor torque in the knee joint was calculated using inverse dynamics. Isometric contractions were performed at eight joint angle configurations of the lower limb corresponding to increments of 10° at the knee from 30 to 100° of knee flexion. Concentric and eccentric contractions were performed over the same range of motion at mean angular velocities of the knee from 30 to 240° s(-1). For contractions of increasing velocity, optimum knee angle shifted from 52 ± 7 to 64 ± 4° knee flexion. Furthermore, the curvature of the concentric force/torque-angular velocity relations varied with joint angles and maximum angular velocities increased from 866 ± 79 to 1,238 ± 132° s(-1) for 90-50° knee flexion. Normalised eccentric forces/torques ranged from 0.85 ± 0.12 to 1.32 ± 0.16 of their isometric reference, only showing significant increases above isometric and an effect of angular velocity for joint angles greater than optimum knee angle. The findings reveal that force/torque production during multi-joint leg extension depends on the combined effects of angle and angular velocity. This finding should be accounted for in modelling and optimisation of human movement.

Compound Leaf Development and Evolution in the Legumes[W

PubMed Central

Champagne, Connie E.M.; Goliber, Thomas E.; Wojciechowski, Martin F.; Mei, Raymond W.; Townsley, Brad T.; Wang, Kan; Paz, Margie M.; Geeta, R.; Sinha, Neelima R.

2007-01-01

Across vascular plants, Class 1 KNOTTED1-like (KNOX1) genes appear to play a critical role in the development of compound leaves. An exception to this trend is found in the Fabaceae, where pea (Pisum sativum) uses UNIFOLIATA, an ortholog of the floral regulators FLORICAULA (FLO) and LEAFY (LFY), in place of KNOX1 genes to regulate compound leaf development. To assess the phylogenetic distribution of KNOX1-independent compound leaf development, a survey of KNOX1 protein expression across the Fabaceae was undertaken. The majority of compound-leafed Fabaceae have expression of KNOX1 proteins associated with developing compound leaves. However, in a large subclade of the Fabaceae, the inverted repeat–lacking clade (IRLC), of which pea is a member, KNOX1 expression is not associated with compound leaves. These data suggest that the FLO/LFY gene may function in place of KNOX1 genes in generating compound leaves throughout the IRLC. The contribution of FLO/LFY to leaf complexity in a member of the Fabaceae outside of the IRLC was examined by reducing expression of FLO/LFY orthologs in transgenic soybean (Glycine max). Transgenic plants with reduced FLO/LFY expression showed only slight reductions in leaflet number. Overexpression of a KNOX1 gene in alfalfa (Medicago sativa), a member of the IRLC, resulted in an increase in leaflet number. This implies that KNOX1 targets, which promote compound leaf development, are present in alfalfa and are still sensitive to KNOX1 regulation. These data suggest that KNOX1 genes and the FLO/LFY gene may have played partially overlapping roles in compound leaf development in ancestral Fabaceae but that the FLO/LFY gene took over this role in the IRLC. PMID:17993625

Show Me the Money: Impact of County Funding on Retention Rates for Extension Educators

ERIC Educational Resources Information Center

Feldhues, Katherine; Tanner, Timothy

2017-01-01

Extension administrators contemplating the challenge of employee turnover should consider potential motivation factors. Through the lens of Herzberg's motivation-hygiene theory, we explored the relationship between financial uncertainty and employee turnover in Ohio State University Extension. The Human Resources department and Business Office of…

Regulatory interplay between LEAFY, APETALA1/CAULIFLOWER and TERMINAL FLOWER1: New insights into an old relationship.

PubMed

Serrano-Mislata, Antonio; Goslin, Kevin; Zheng, Beibei; Rae, Liina; Wellmer, Frank; Graciet, Emmanuelle; Madueño, Francisco

2017-10-03

The gene regulatory network comprised of LEAFY (LFY), APETALA1 (AP1), the AP1 paralog CAULIFLOWER (CAL), and TERMINAL FLOWER1 (TFL1) is a major determinant of the flowering process in Arabidopsis thaliana. TFL1 activity in the shoot apical meristem provides inflorescence identity while the transcription factors LFY and AP1/CAL confer floral identity to emerging floral primordia. It has been thought that LFY and AP1/CAL control the onset of flowering in part by repressing TFL1 expression in flowers. However, in the June issue of Plant Physiology, we reported that LFY and AP1 act antagonistically in the regulation of several key flowering regulators, including TFL1. Specifically, TFL1 transcription was suppressed by AP1 but promoted by LFY. Here, we present additional evidence for the role of LFY as an activator of TFL1 and propose that this regulatory activity is pivotal for the indeterminate growth of the SAM during the reproductive phase of development.

Effect of feed intake restriction on reproductive performance and pregnancy rate in Egyptian buffalo heifers.

PubMed

Hussein, Hassan Ali; Abdel-Raheem, Sherief Mohamed

2013-04-01

The objective of the present experiment is to study the effect of feed intake restriction on the reproductive performance and pregnancy rate in Egyptian buffalo heifers. Thirty anestrus buffalo heifers were randomly divided into two equal groups. The low feed intake (LFI, n=15, 50 % restriction) group was fed a diet that consists of 3 kg concentrate, 1 kg wheat straw, and 3 kg fresh alfalfa, while the high feed intake (HFI, n=15) group was fed double the amount given to the LFI group for 4 months. All animals were weighed, transrectally examined, and visually checked for the signs of estrus, and blood samples were collected. Heifers in heat were mated with one fertile bull. The number of heifers showing estrus activity was 93.3 % in HFI vs. 20 % in LFI (P<0.01). Ovarian activity started earlier (P=0.03) in the HFI than LFI group. The weight at breeding, the diameter of the dominant follicle, number of heifers showing ovulations, number of services per conception, pregnancy rate, and overall mean of progesterone and estrogen concentrations were significantly higher (P<0.01) in the HFI than in the LFI group. The level of serum total protein, albumin, globulin, glucose, total cholesterol, and calcium were significantly higher (P<0.05) in the HFI group. Restriction of the daily feed intake to 50 % from NRC recommendations impair reproductive performance in terms of increasing the age at first service and reducing the pregnancy rate in buffalo heifers. In conclusion, feed intake could be effective in improvement of reproductive performance in buffalo heifers and further studies should be done on large scale of buffaloes in this point.

Evolution of the Plant Reproduction Master Regulators LFY and the MADS Transcription Factors: The Role of Protein Structure in the Evolutionary Development of the Flower.

PubMed

Silva, Catarina S; Puranik, Sriharsha; Round, Adam; Brennich, Martha; Jourdain, Agnès; Parcy, François; Hugouvieux, Veronique; Zubieta, Chloe

2015-01-01

Understanding the evolutionary leap from non-flowering (gymnosperms) to flowering (angiosperms) plants and the origin and vast diversification of the floral form has been one of the focuses of plant evolutionary developmental biology. The evolving diversity and increasing complexity of organisms is often due to relatively small changes in genes that direct development. These "developmental control genes" and the transcription factors (TFs) they encode, are at the origin of most morphological changes. TFs such as LEAFY (LFY) and the MADS-domain TFs act as central regulators in key developmental processes of plant reproduction including the floral transition in angiosperms and the specification of the male and female organs in both gymnosperms and angiosperms. In addition to advances in genome wide profiling and forward and reverse genetic screening, structural techniques are becoming important tools in unraveling TF function by providing atomic and molecular level information that was lacking in purely genetic approaches. Here, we summarize previous structural work and present additional biophysical and biochemical studies of the key master regulators of plant reproduction - LEAFY and the MADS-domain TFs SEPALLATA3 and AGAMOUS. We discuss the impact of structural biology on our understanding of the complex evolutionary process leading to the development of the bisexual flower.

Evolution of the Plant Reproduction Master Regulators LFY and the MADS Transcription Factors: The Role of Protein Structure in the Evolutionary Development of the Flower

PubMed Central

Silva, Catarina S.; Puranik, Sriharsha; Round, Adam; Brennich, Martha; Jourdain, Agnès; Parcy, François; Hugouvieux, Veronique; Zubieta, Chloe

2016-01-01

Understanding the evolutionary leap from non-flowering (gymnosperms) to flowering (angiosperms) plants and the origin and vast diversification of the floral form has been one of the focuses of plant evolutionary developmental biology. The evolving diversity and increasing complexity of organisms is often due to relatively small changes in genes that direct development. These “developmental control genes” and the transcription factors (TFs) they encode, are at the origin of most morphological changes. TFs such as LEAFY (LFY) and the MADS-domain TFs act as central regulators in key developmental processes of plant reproduction including the floral transition in angiosperms and the specification of the male and female organs in both gymnosperms and angiosperms. In addition to advances in genome wide profiling and forward and reverse genetic screening, structural techniques are becoming important tools in unraveling TF function by providing atomic and molecular level information that was lacking in purely genetic approaches. Here, we summarize previous structural work and present additional biophysical and biochemical studies of the key master regulators of plant reproduction – LEAFY and the MADS-domain TFs SEPALLATA3 and AGAMOUS. We discuss the impact of structural biology on our understanding of the complex evolutionary process leading to the development of the bisexual flower. PMID:26779227

Genomic patterns in Acropora cervicornis show extensive population structure and variable genetic diversity.

PubMed

Drury, Crawford; Schopmeyer, Stephanie; Goergen, Elizabeth; Bartels, Erich; Nedimyer, Ken; Johnson, Meaghan; Maxwell, Kerry; Galvan, Victor; Manfrino, Carrie; Lirman, Diego

2017-08-01

Threatened Caribbean coral communities can benefit from high-resolution genetic data used to inform management and conservation action. We use Genotyping by Sequencing (GBS) to investigate genetic patterns in the threatened coral, Acropora cervicornis , across the Florida Reef Tract (FRT) and the western Caribbean. Results show extensive population structure at regional scales and resolve previously unknown structure within the FRT. Different regions also exhibit up to threefold differences in genetic diversity (He), suggesting targeted management based on the goals and resources of each population is needed. Patterns of genetic diversity have a strong spatial component, and our results show Broward and the Lower Keys are among the most diverse populations in Florida. The genetic diversity of Caribbean staghorn coral is concentrated within populations and within individual reefs (AMOVA), highlighting the complex mosaic of population structure. This variance structure is similar over regional and local scales, which suggests that in situ nurseries are adequately capturing natural patterns of diversity, representing a resource that can replicate the average diversity of wild assemblages, serving to increase intraspecific diversity and potentially leading to improved biodiversity and ecosystem function. Results presented here can be translated into specific goals for the recovery of A. cervicornis , including active focus on low diversity areas, protection of high diversity and connectivity, and practical thresholds for responsible restoration.

Effect of corn silage hybrids differing in starch and neutral detergent fiber digestibility on lactation performance and total-tract nutrient digestibility by dairy cows.

PubMed

Ferraretto, L F; Fonseca, A C; Sniffen, C J; Formigoni, A; Shaver, R D

2015-01-01

Selection for hybrids with greater starch and NDF digestibility may be beneficial for dairy producers. The objective of this study was to determine the effect of feeding a TMR containing a floury-leafy corn silage hybrid (LFY) compared with a brown midrib corn silage hybrid (BMR) for intake, lactation performance, and total-tract nutrient digestibility in dairy cows. Ninety-six multiparous Holstein cows, 105±31d in milk at trial initiation, were stratified by DIM and randomly assigned to 12 pens of 8 cows each. Pens were randomly assigned to 1 of 2 treatments, BMR or LFY, in a completely randomized design; a 2-wk covariate period with cows fed a common diet followed by a 14-wk treatment period with cows fed their assigned treatment diet. Starch digestibilities, in situ, in vitro, and in vivo, were greater for LFY compared with BMR; the opposite was observed for NDF digestibility. Cows fed BMR consumed 1.7kg/d more dry matter than LFY. Although, actual-, energy-, and solids-corrected milk yields were greater for BMR than LFY, feed conversions (kg of milk or component-corrected milk per kg of DMI) did not differ. Fat-corrected milk and milk fat yield were similar, as milk fat content was greater for cows fed LFY (4.05%) than BMR (3.83%). Cows fed BMR had lower milk urea nitrogen concentration, but greater milk protein and lactose yields compared with LFY. Body weight change and condition score were unaffected by treatment. Total-tract starch digestibility was greater for cows fed the LFY corn silage; however, dry matter intake and milk and protein yields were greater for cows fed the BMR corn silage. Although total-tract starch digestibility was greater for cows fed the LFY corn silage, feed efficiency was not affected by hybrid type due to greater dry matter intake and milk and protein yields by cows fed the BMR corn silage. Copyright © 2015 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

LEAFY blossoms.

PubMed

Moyroud, Edwige; Kusters, Elske; Monniaux, Marie; Koes, Ronald; Parcy, François

2010-06-01

The LEAFY (LFY) gene of Arabidopsis and its homologs in other angiosperms encode a unique plant-specific transcription factor that assigns the floral fate of meristems and plays a key role in the patterning of flowers, probably since the origin of flowering plants. LFY-like genes are also found in gymnosperms, ferns and mosses that do not produce flowers, but their role in these plants is poorly understood. Here, we review recent findings explaining how the LFY protein works and how it could have evolved throughout land plant history. We propose that LFY homologs have an ancestral role in regulating cell division and arrangement, and acquired novel functions in seed plants, such as activating reproductive gene networks.

18 CFR 12.38 - Time for inspections and reports.

Code of Federal Regulations, 2011 CFR

2011-04-01

... reaches its normal maximum surface elevation, whichever occurs first. (3) For any development not set... information and analyses required by § 12.37(b). (c) Extension of time. For good cause shown, the Regional...

Activation of the Arabidopsis B class homeotic genes by APETALA1.

PubMed

Ng, M; Yanofsky, M F

2001-04-01

Proper development of petals and stamens in Arabidopsis flowers requires the activities of APETALA3 (AP3) and PISTILLATA (PI), whose transcripts can be detected in the petal and stamen primordia. Localized expression of AP3 and PI requires the activities of at least three genes: APETALA1 (AP1), LEAFY (LFY), and UNUSUAL FLORAL ORGANS (UFO). It has been proposed that UFO provides spatial cues and that LFY specifies competence for AP3 and PI expression in the developing flower. To understand the epistatic relationship among AP1, LFY, and UFO in regulating AP3 and PI expression, we generated two versions of AP1 that have strong transcriptional activation potential. Genetic and molecular analyses of transgenic plants expressing these activated AP1 proteins show that the endogenous AP1 protein acts largely as a transcriptional activator in vivo and that AP1 specifies petals by regulating the spatial domains of AP3 and PI expression through UFO.

Cold adapted features of Vibrio salmonicida catalase: characterisation and comparison to the mesophilic counterpart from Proteus mirabilis.

PubMed

Lorentzen, Marit Sjo; Moe, Elin; Jouve, Hélène Marie; Willassen, Nils Peder

2006-10-01

The gene encoding catalase from the psychrophilic marine bacterium Vibrio salmonicida LFI1238 was identified, cloned and expressed in the catalase-deficient Escherichia coli UM2. Recombinant catalase from V. salmonicida (VSC) was purified to apparent homogeneity as a tetramer with a molecular mass of 235 kDa. VSC contained 67% heme b and 25% protoporphyrin IX. VSC was able to bind NADPH, react with cyanide and form compounds I and II as other monofunctional small subunit heme catalases. Amino acid sequence alignment of VSC and catalase from the mesophilic Proteus mirabilis (PMC) revealed 71% identity. As for cold adapted enzymes in general, VSC possessed a lower temperature optimum and higher catalytic efficiency (k (cat)/K (m)) compared to PMC. VSC have higher affinity for hydrogen peroxide (apparent K (m)) at all temperatures. For VSC the turnover rate (k (cat)) is slightly lower while the catalytic efficiency is slightly higher compared to PMC over the temperature range measured, except at 4 degrees C. Moreover, the catalytic efficiency of VSC and PMC is almost temperature independent, except at 4 degrees C where PMC has a twofold lower efficiency compared to VSC. This may indicate that VSC has evolved to maintain a high efficiency at low temperatures.

The poetry of reproduction: the role of LEAFY in Arabidopsis thaliana flower formation.

PubMed

Siriwardana, Nirodhini S; Lamb, Rebecca S

2012-01-01

For successful reproduction, angiosperms must form fertile flowers at the appropriate positions and at the appropriate times. The reproductive transition is especially important for monocarpic plants that only flower once. In the model annual plant Arabidopsis thaliana, this transition is controlled through regulation of a group of genes termed floral meristem identity genes, of which LEAFY (LFY) is arguably the most important. LFY orthologs are found throughout land plants and are essential for angiosperm reproduction. These genes have also been implicated in reproductive development in gymnosperms. LFY encodes a plant-specific transcription factor that can act as either an activator or repressor depending on context, including what co-factors it is interacting with. It controls multiple aspects of floral morphogenesis, including phyllotaxis, organ number, organ identity and determinacy. Much progress has been made in elucidating the molecular mechanisms through which LFY and its orthologs contribute to a precise switch to flowering. We discuss the current state of knowledge in Arabidopsis, with an emphasis on known target genes and co-factors of LFY.

Effects of sound intensity on temporal properties of inhibition in the pallid bat auditory cortex.

PubMed

Razak, Khaleel A

2013-01-01

Auditory neurons in bats that use frequency modulated (FM) sweeps for echolocation are selective for the behaviorally-relevant rates and direction of frequency change. Such selectivity arises through spectrotemporal interactions between excitatory and inhibitory components of the receptive field. In the pallid bat auditory system, the relationship between FM sweep direction/rate selectivity and spectral and temporal properties of sideband inhibition have been characterized. Of note is the temporal asymmetry in sideband inhibition, with low-frequency inhibition (LFI) exhibiting faster arrival times compared to high-frequency inhibition (HFI). Using the two-tone inhibition over time (TTI) stimulus paradigm, this study investigated the interactions between two sound parameters in shaping sideband inhibition: intensity and time. Specifically, the impact of changing relative intensities of the excitatory and inhibitory tones on arrival time of inhibition was studied. Using this stimulation paradigm, single unit data from the auditory cortex of pentobarbital-anesthetized cortex show that the threshold for LFI is on average ~8 dB lower than HFI. For equal intensity tones near threshold, LFI is stronger than HFI. When the inhibitory tone intensity is increased further from threshold, the strength asymmetry decreased. The temporal asymmetry in LFI vs. HFI arrival time is strongest when the excitatory and inhibitory tones are of equal intensities or if excitatory tone is louder. As inhibitory tone intensity is increased, temporal asymmetry decreased suggesting that the relative magnitude of excitatory and inhibitory inputs shape arrival time of inhibition and FM sweep rate and direction selectivity. Given that most FM bats use downward sweeps as echolocation calls, a similar asymmetry in threshold and strength of LFI vs. HFI may be a general adaptation to enhance direction selectivity while maintaining sweep-rate selective responses to downward sweeps.

Molecular evolution of Adh and LEAFY and the phylogenetic utility of their introns in Pyrus (Rosaceae)

PubMed Central

2011-01-01

Background The genus Pyrus belongs to the tribe Pyreae (the former subfamily Maloideae) of the family Rosaceae, and includes one of the most important commercial fruit crops, pear. The phylogeny of Pyrus has not been definitively reconstructed. In our previous efforts, the internal transcribed spacer region (ITS) revealed a poorly resolved phylogeny due to non-concerted evolution of nrDNA arrays. Therefore, introns of low copy nuclear genes (LCNG) are explored here for improved resolution. However, paralogs and lineage sorting are still two challenges for applying LCNGs in phylogenetic studies, and at least two independent nuclear loci should be compared. In this work the second intron of LEAFY and the alcohol dehydrogenase gene (Adh) were selected to investigate their molecular evolution and phylogenetic utility. Results DNA sequence analyses revealed a complex ortholog and paralog structure of Adh genes in Pyrus and Malus, the pears and apples. Comparisons between sequences from RT-PCR and genomic PCR indicate that some Adh homologs are putatively nonfunctional. A partial region of Adh1 was sequenced for 18 Pyrus species and three subparalogs representing Adh1-1 were identified. These led to poorly resolved phylogenies due to low sequence divergence and the inclusion of putative recombinants. For the second intron of LEAFY, multiple inparalogs were discovered for both LFY1int2 and LFY2int2. LFY1int2 is inadequate for phylogenetic analysis due to lineage sorting of two inparalogs. LFY2int2-N, however, showed a relatively high sequence divergence and led to the best-resolved phylogeny. This study documents the coexistence of outparalogs and inparalogs, and lineage sorting of these paralogs and orthologous copies. It reveals putative recombinants that can lead to incorrect phylogenetic inferences, and presents an improved phylogenetic resolution of Pyrus using LFY2int2-N. Conclusions Our study represents the first phylogenetic analyses based on LCNGs in Pyrus

The structure of S . lividans acetoacetyl-CoA synthetase shows a novel interaction between the C-terminal extension and the N-terminal domain

DOE PAGES

Mitchell, Carter A.; Tucker, Alex C.; Escalante-Semerena, Jorge C.; ...

2014-12-09

The adenosine monoposphate-forming acyl-CoA synthetase enzymes catalyze a two-step reaction that involves the initial formation of an acyl adenylate that reacts in a second partial reaction to form a thioester between the acyl substrate and CoA. These enzymes utilize a Domain Alternation catalytic mechanism, whereby a ~110 residue C-terminal domain rotates by 140° to form distinct catalytic conformations for the two partial reactions. In this paper, the structure of an acetoacetyl-CoA synthetase (AacS) is presented that illustrates a novel aspect of this C-terminal domain. Specifically, several acetyl- and acetoacetyl-CoA synthetases contain a 30-residue extension on the C-terminus compared to othermore » members of this family. Finally, whereas residues from this extension are disordered in prior structures, the AacS structure shows that residues from this extension may interact with key catalytic residues from the N-terminal domain.« less

Flexion and extension gaps created by the navigation-assisted gap technique show small acceptable mismatches and close mutual correlations.

PubMed

Lee, Dae-Hee; Shin, Young-Soo; Jeon, Jin-Ho; Suh, Dong-Won; Han, Seung-Beom

2014-08-01

The aim of this study was to investigate the mechanism underlying the development of gap differences in total knee arthroplasty using the navigation-assisted gap technique and to assess whether these gap differences have statistical significance. Ninety-two patients (105 knees) implanted with cruciate-retaining prostheses using the navigation-assisted gap balancing technique were prospectively analysed. Medial extension and flexion gaps and lateral extension and flexion gaps were measured at full extension and at 90° of flexion. Repeated measures analysis of variance was used to compare the mean values of these four gaps. The correlation coefficient between each pair of gaps was assessed using Pearson's correlation analysis. Mean intra-operative medial and lateral extension gaps were 20.6 ± 2.1 and 21.7 ± 2.2 mm, respectively, and mean intra-operative medial and lateral flexion gaps were 21.6 ± 2.7 and 22.1 ± 2.5 mm, respectively. The pairs of gaps differed significantly (P < 0.05 each), except for the difference between the medial flexion and lateral extension gaps (n.s.). All four gaps were significantly correlated with each other, with the highest correlation between the medial and lateral flexion gaps (r = 0.890, P < 0.001) and the lowest between the medial flexion and lateral extension gaps (r = 0.701, P < 0.001). Medial and lateral flexion and extension gaps created using the navigation-assisted gap technique differed significantly, although the differences between them were <2 mm, and the gaps were closely correlated. These narrow ranges of statistically acceptable gap differences and the strong correlations between gaps should be considered by surgeons, as should the risks of soft tissue over-release or unintentional increases in extension or flexion gap after preparation of the other gap.

Development of a model based on biochemical, real-time tissue elastography and ultrasound data for the staging of liver fibrosis and cirrhosis in patients with chronic hepatitis B

PubMed Central

Xu, Shi-Hao; Li, Qiao; Hu, Yuan-Ping; Ying, Li

2016-01-01

The liver fibrosis index (LFI), based on real-time tissue elastography (RTE), is a method currently used to assess liver fibrosis. However, this method may not consistently distinguish between the different stages of fibrosis, which limits its accuracy. The aim of the present study was to develop novel models based on biochemical, RTE and ultrasound data for predicting significant liver fibrosis and cirrhosis. A total of 85 consecutive patients with chronic hepatitis B (CHB) were prospectively enrolled and underwent a liver biopsy and RTE. The parameters for predicting significant fibrosis and cirrhosis were determined by conducting multivariate analyses. The splenoportal index (SPI; P=0.002) and LFI (P=0.023) were confirmed as independent predictors of significant fibrosis. Using multivariate analyses for identifying parameters that predict cirrhosis, significant differences in γ-glutamyl transferase (GGT; P=0.049), SPI (P=0.002) and LFI (P=0.001) were observed. Based on these observations, the novel model LFI-SPI score (LSPS) was developed to predict the occurrence of significant liver fibrosis, with an area under receiver operating characteristic curves (AUROC) of 0.87. The diagnostic accuracy of the LSPS model was superior to that of the LFI (AUROC=0.76; P=0.0109), aspartate aminotransferase-to-platelet ratio index (APRI; AUROC=0.64; P=0.0031), fibrosis-4 index (FIB-4; AUROC= 0.67; P= 0.0044) and FibroScan (AUROC=0.68; P=0.0021) models. In addition, the LFI-SPI-GGT score (LSPGS) was developed for the purposes of predicting liver cirrhosis, demonstrating an AUROC value of 0.93. The accuracy of LSPGS was similar to that of FibroScan (AUROC=0.85; P=0.134), but was superior to LFI (AUROC= 0.81; P= 0.0113), APRI (AUROC= 0.67; P<0.0001) and FIB-4 (AUROC=0.719; P=0.0005). In conclusion, the results of the present study suggest that the use of LSPS and LSPGS may complement current methods of diagnosing significant liver fibrosis and cirrhosis in patients with CHB

Midfacial Changes Through Anterior Maxillary Distraction Osteogenesis in Patients With Cleft Lip and Palate.

PubMed

Kanzaki, Hiroyuki; Imai, Yoshimichi; Nakajo, Tetsu; Daimaruya, Takayoshi; Sato, Akimitsu; Tachi, Masahiro; Nunomura, Youhei; Itagaki, Yusuke; Nishimura, Kazuaki; Kochi, Shoko; Igarashi, Kaoru

2017-06-01

Maxillary hypoplasia is a major issue in cleft lip and palate patients, and predictable surgical maxillary advancement is required. In the present study, the changes and stability of the maxilla and soft tissue profile achieved after the application of anterior maxillary distraction osteogenesis (AMDO) using intraoral expander in unilateral cleft lip and palate and isolated cleft palate patients were investigated by comparing to the Le Fort I osteotomy (LFI) and maxillary distraction osteogenesis (DO) with rigid external distraction (RED) system.Ten patients who underwent orthognathic treatment with AMDO were examined (AMDO group). Changes in the positions of soft and hard tissue landmarks were calculated from the lateral cephalograms taken before the distraction, at the end of the distraction, and 1 year after the surgery. They were compared with the changes in 7 other unilateral cleft lip and palate patients who underwent LFI (LFI group) and 6 others who underwent DO with RED (RED group).The mean maxillary advancement of the AMDO group was similar to that of the RED group, judged by the change of point A. During DO, the AMDO group showed less clockwise rotation of mandible compared to the RED group. The soft tissue advancement of the upper lip and nose in the AMDO group was similar to that in the RED group, which was significantly larger than that in the LFI group.Our results indicate that AMDO can be surgical option to cleft lip and palate patients with less invasive but excellent improvement in both midfacial skeletal and soft tissue similar to DO-RED.

Planck 2015 Cosmological results

NASA Astrophysics Data System (ADS)

Tristram, Matthieu

2015-08-01

On behalf of the Planck collaboration, I will present the cosmological results from the 2015 release. The new release now include polarization data from both the LFI and the HFI.I will focus on the impact of the polarization on both the standard LCDM model and its basic extensions. I will compare these constraints with other cosmological probes such as BAO, gravitational lensing and redshift space distortions.LCDM is still a very good fit of the Planck CMB data. The scalar fluctuations are consistent with adiabatic modes.

Increasing threat of landfalling typhoons in the western North Pacific between 1974 and 2013

NASA Astrophysics Data System (ADS)

Guan, Shoude; Li, Shuiqing; Hou, Yijun; Hu, Po; Liu, Ze; Feng, Junqiao

2018-06-01

Long-term changes between 1974 and 2013 were investigated in western North Pacific typhoons making landfall in East and Southeast Asia. Landfalling typhoon parameters, including the percentage of typhoons making landfall, the annual mean landfall intensity (LFI), and the annual accumulated power dissipation index at land, all increased significantly (at the 99% confidence level), by 14%, 17%, and 94%, respectively, over the study period. The increase in probability of a typhoon making landfall was attributed to an eastward shift of the typhoon genesis location. The LFI was decomposed into the product of the intensification rate and intensification duration. The product reproduced variations in the observed LFI well, and the correlation coefficient was high at 0.82. Although the intensification duration decreased slightly, an unprecedented increase in the intensification rate was observed, this increased the LFI. Warming of the upper ocean in the western North Pacific typhoon main intensification region, giving a higher tropical cyclone heat potential, yielded better oceanic conditions and overcame the worsening atmospheric conditions (increasing vertical wind shear), allowing typhoons to intensify. The increase in the annual accumulated power dissipation index was mainly caused by the increase in the LFI, and the annual number of typhoons and typhoon duration contributed much less. Increasing typhoon landfalling activities might heighten the threat posed by typhoons to populations and infrastructure in coastal regions.

Effect of ruminal acidosis and short-term low feed intake on indicators of gastrointestinal barrier function in Holstein steers.

PubMed

Pederzolli, Rae-Leigh A; Van Kessel, Andrew G; Campbell, John; Hendrick, Steve; Wood, Katie M; Penner, Gregory B

2018-02-15

The objective of this study was to determine effect of ruminal acidosis (RA) and low feed intake [LFI] on the regional barrier function of the gastrointestinal tract. Twenty-one Holstein steers were fed for ad libitum intake for 5 d (control [CON]), fed at 25% of ad libitum intake for 5 d (LFI), or provided 2 d of ad libitum intake followed by 1-d of feed restriction (25% of ad libitum intake), 1 d where 30% of ad libitum dry matter intake (DMI) was provided as pelleted barley followed by the full allocation (RA) and fed for ad libitum intake the following day. Tissues and digesta from the rumen, omasum, duodenum, jejunum, ileum, cecum, proximal, and distal colon were collected. Permeability was assessed using the mucosal-to-serosal flux of inulin (JMS-inulin) and mannitol (JMS-mannitol). Digesta pH was 0.81, 0.63, and 0.42 pH units less for RA than CON in the rumen, cecum, and proximal colon; while, LFI had pH that was 0.47 and 0.36 pH units greater in the rumen and proximal colon compared to CON. Total ruminal short-chain fatty acid (SCFA) concentration were less for LFI (92 mM; P = 0.010) and RA (87 mM; P = 0.007) than CON (172 mM) steers. In the proximal colon, the proportion of butyrate (P = 0.025 and P = 0.022) and isobutyrate (P = 0.019 and P = 0.019) were greater, and acetate (P = 0.028 and P = 0.028) was less for LFI and RA, respectively, when compared to CON steers. Ruminal papillae length, width, perimeter, and surface area were 1.21 mm, 0.78 mm, 3.84 mm, and 11.15 mm2 less for LFI than CON; while, RA decreased papillae width by 0.52 mm relative to CON. The JMS-mannitol was less for LFI steers than CON in the proximal colon (P = 0.041) and in the distal colon (P = 0.015). Increased gene expression for claudin 1, occludin, tight-cell junction protein 1 and 2, and toll-like receptor 4 were detected for LFI relative to CON in the rumen, jejunum, and proximal colon. For RA steers, expression of toll-like receptor 4 in the rumen, and occludin and tight

Evaluation of a new nanoparticle-based lateral-flow immunoassay for the exclusion of heparin-induced thrombocytopenia (HIT).

PubMed

Sachs, Ulrich J; von Hesberg, Jakob; Santoso, Sentot; Bein, Gregor; Bakchoul, Tamam

2011-12-01

Heparin-induced thrombocytopenia (HIT) is an adverse complication of heparin caused by HIT antibodies (abs) that recognise platelet factor 4-heparin (PF4/hep) complexes. Several laboratory tests are available for the confirmation and/or refutation of HIT. A reliable and rapid single-sample test is still pending. It was the objective of this study to evaluate a new lateral-flow immunoassay based on nanoparticle technology. A cohort of 452 surgical and medical patients suspected of having HIT was evaluated. All samples were tested in two IgG-specific ELISAs, in a particle gel immunoassay (PaGIA) and in a newly developed lateral-flow immunoassay (LFI-HIT) as well as in a functional test (HIPA). Clinical pre-test probability was determined using 4T's score. Platelet-activating antibodies were present in 34/452 patients, all of whom had intermediate to high clinical probability. PF4/hep abs were detected in 79, 87, 86, and 63 sera using the four different immunoassays. The negative predictive values (NPV) were 100% for both ELISA tests and LFI-HIT but only 99.2% for PaGIA. There were less false positives (n=29) in the LFI-HIT compared to any other test. Additionally, significantly less time was required to perform LFI-HIT than to perform the other immunoassays. In conclusion, a newly developed lateral-flow assay, LFI-HIT, was capable of identifying all HIT patients in a cohort in a short period of time. Beside an NPV of 100%, the rate of false-positive signals is significantly lower with LFI-HIT than with other immunoassay(s). These performance characteristics suggest a high potency in reducing the risk and costs in patients suspected of having HIT.

PKA and PKC Are Required for Long-Term but Not Short-Term in Vivo Operant Memory in "Aplysia"

ERIC Educational Resources Information Center

Michel, Maximilian; Green, Charity L.; Lyons, Lisa C.

2011-01-01

We investigated the involvement of PKA and PKC signaling in a negatively reinforced operant learning paradigm in "Aplysia", learning that food is inedible (LFI). In vivo injection of PKA or PKC inhibitors blocked long-term LFI memory formation. Moreover, a persistent phase of PKA activity, although not PKC activity, was necessary for long-term…

Planck 2015 results. II. Low Frequency Instrument data processings

NASA Astrophysics Data System (ADS)

Planck Collaboration; Ade, P. A. R.; Aghanim, N.; Ashdown, M.; Aumont, J.; Baccigalupi, C.; Ballardini, M.; Banday, A. J.; Barreiro, R. B.; Bartolo, N.; Basak, S.; Battaglia, P.; Battaner, E.; Benabed, K.; Benoît, A.; Benoit-Lévy, A.; Bernard, J.-P.; Bersanelli, M.; Bielewicz, P.; Bock, J. J.; Bonaldi, A.; Bonavera, L.; Bond, J. R.; Borrill, J.; Bouchet, F. R.; Bucher, M.; Burigana, C.; Butler, R. C.; Calabrese, E.; Cardoso, J.-F.; Castex, G.; Catalano, A.; Chamballu, A.; Christensen, P. R.; Colombi, S.; Colombo, L. P. L.; Crill, B. P.; Curto, A.; Cuttaia, F.; Danese, L.; Davies, R. D.; Davis, R. J.; de Bernardis, P.; de Rosa, A.; de Zotti, G.; Delabrouille, J.; Dickinson, C.; Diego, J. M.; Dole, H.; Donzelli, S.; Doré, O.; Douspis, M.; Ducout, A.; Dupac, X.; Efstathiou, G.; Elsner, F.; Enßlin, T. A.; Eriksen, H. K.; Fergusson, J.; Finelli, F.; Forni, O.; Frailis, M.; Franceschet, C.; Franceschi, E.; Frejsel, A.; Galeotta, S.; Galli, S.; Ganga, K.; Giard, M.; Giraud-Héraud, Y.; Gjerløw, E.; González-Nuevo, J.; Górski, K. M.; Gratton, S.; Gregorio, A.; Gruppuso, A.; Hansen, F. K.; Hanson, D.; Harrison, D. L.; Henrot-Versillé, S.; Herranz, D.; Hildebrandt, S. R.; Hivon, E.; Hobson, M.; Holmes, W. A.; Hornstrup, A.; Hovest, W.; Huffenberger, K. M.; Hurier, G.; Jaffe, A. H.; Jaffe, T. R.; Juvela, M.; Keihänen, E.; Keskitalo, R.; Kiiveri, K.; Kisner, T. S.; Knoche, J.; Krachmalnicoff, N.; Kunz, M.; Kurki-Suonio, H.; Lagache, G.; Lähteenmäki, A.; Lamarre, J.-M.; Lasenby, A.; Lattanzi, M.; Lawrence, C. R.; Leahy, J. P.; Leonardi, R.; Lesgourgues, J.; Levrier, F.; Liguori, M.; Lilje, P. B.; Linden-Vørnle, M.; Lindholm, V.; López-Caniego, M.; Lubin, P. M.; Macías-Pérez, J. F.; Maggio, G.; Maino, D.; Mandolesi, N.; Mangilli, A.; Maris, M.; Martin, P. G.; Martínez-González, E.; Masi, S.; Matarrese, S.; Mazzotta, P.; McGehee, P.; Meinhold, P. R.; Melchiorri, A.; Mendes, L.; Mennella, A.; Migliaccio, M.; Mitra, S.; Montier, L.; Morgante, G.; Morisset, N.; Mortlock, D.; Moss, A.; Munshi, D.; Murphy, J. A.; Naselsky, P.; Nati, F.; Natoli, P.; Netterfield, C. B.; Nørgaard-Nielsen, H. U.; Novikov, D.; Novikov, I.; Oppermann, N.; Paci, F.; Pagano, L.; Paoletti, D.; Partridge, B.; Pasian, F.; Patanchon, G.; Pearson, T. J.; Peel, M.; Perdereau, O.; Perotto, L.; Perrotta, F.; Pettorino, V.; Piacentini, F.; Pierpaoli, E.; Pietrobon, D.; Pointecouteau, E.; Polenta, G.; Pratt, G. W.; Prézeau, G.; Prunet, S.; Puget, J.-L.; Rachen, J. P.; Rebolo, R.; Reinecke, M.; Remazeilles, M.; Renzi, A.; Rocha, G.; Romelli, E.; Rosset, C.; Rossetti, M.; Roudier, G.; Rubiño-Martín, J. A.; Rusholme, B.; Sandri, M.; Santos, D.; Savelainen, M.; Scott, D.; Seiffert, M. D.; Shellard, E. P. S.; Spencer, L. D.; Stolyarov, V.; Sutton, D.; Suur-Uski, A.-S.; Sygnet, J.-F.; Tauber, J. A.; Tavagnacco, D.; Terenzi, L.; Toffolatti, L.; Tomasi, M.; Tristram, M.; Tucci, M.; Tuovinen, J.; Türler, M.; Umana, G.; Valenziano, L.; Valiviita, J.; Van Tent, B.; Vassallo, T.; Vielva, P.; Villa, F.; Wade, L. A.; Wandelt, B. D.; Watson, R.; Wehus, I. K.; Wilkinson, A.; Yvon, D.; Zacchei, A.; Zonca, A.

2016-09-01

We present an updated description of the Planck Low Frequency Instrument (LFI) data processing pipeline, associated with the 2015 data release. We point out the places where our results and methods have remained unchanged since the 2013 paper and we highlight the changes made for the 2015 release, describing the products (especially timelines) and the ways in which they were obtained. We demonstrate that the pipeline is self-consistent (principally based on simulations) and report all null tests. For the first time, we present LFI maps in Stokes Q and U polarization. We refer to other related papers where more detailed descriptions of the LFI data processing pipeline may be found if needed.

Differential role of calpain-dependent protein cleavage in intermediate and long-term operant memory in Aplysia.

PubMed

Lyons, Lisa C; Gardner, Jacob S; Lentsch, Cassidy T; Gandour, Catherine E; Krishnan, Harini C; Noakes, Eric J

2017-01-01

In addition to protein synthesis, protein degradation or protein cleavage may be necessary for intermediate (ITM) and long-term memory (LTM) to remove molecular constraints, facilitate persistent kinase activity and modulate synaptic plasticity. Calpains, a family of conserved calcium dependent cysteine proteases, modulate synaptic function through protein cleavage. We used the marine mollusk Aplysia californica to investigate the in vivo role of calpains during intermediate and long-term operant memory formation using the learning that food is inedible (LFI) paradigm. A single LFI training session, in which the animal associates a specific netted seaweed with the failure to swallow, generates short (30min), intermediate (4-6h) and long-term (24h) memory. Using the calpain inhibitors calpeptin and MDL-28170, we found that ITM requires calpain activity for induction and consolidation similar to the previously reported requirements for persistent protein kinase C activity in intermediate-term LFI memory. The induction of LTM also required calpain activity. In contrast to ITM, calpain activity was not necessary for the molecular consolidation of LTM. Surprisingly, six hours after LFI training we found that calpain activity was necessary for LTM, although this is a time at which neither persistent PKC activity nor protein synthesis is required for the maintenance of long-term LFI memory. These results demonstrate that calpains function in multiple roles in vivo during associative memory formation. Copyright © 2016 Elsevier Inc. All rights reserved.

Health extension workers improve tuberculosis case finding and treatment outcome in Ethiopia: a large-scale implementation study

PubMed Central

Datiko, Daniel G; Yassin, Mohammed A; Theobald, Sally J; Blok, Lucie; Suvanand, Sahu; Creswell, Jacob

2017-01-01

Background Tuberculosis (TB) is a major cause of death in Ethiopia. One of the main barriers for TB control is the lack of access to health services. Methods We evaluated a diagnostic and treatment service for TB based on the health extension workers (HEW) of the Ethiopian Health Extension Programme in Sidama Zone, with 3.5 million population. We added the services to the HEW routines and evaluated their effect over 4.5 years. 1024 HEWs were trained to identify individuals with symptoms of TB, request sputum samples and prepare smears. Smears were transported to designated laboratories. Individuals with TB were offered treatment at home or the local health post. A second zone (Hadiya) with 1.2 million population was selected as control. We compared TB case notification rates (CNR) and treatment outcomes in the zones 3 years before and 4.5 years after intervention. Results HEWs identified 216 165 individuals with symptoms and 27 918 (12%) were diagnosed with TB. Smear-positive TB CNR increased from 64 (95% CI 62.5 to 65.8) to 127 (95% CI 123.8 to 131.2) and all forms of TB increased from 102 (95% CI 99.1 to 105.8) to 177 (95% CI 172.6 to 181.0) per 100 000 population in the first year of intervention. In subsequent years, the smear-positive CNR declined by 9% per year. There was no change in CNR in the control area. Treatment success increased from 76% before the intervention to 95% during the intervention. Patients lost to follow-up decreased from 21% to 3% (p<0.001). Conclusion A community-based package significantly increased case finding and improved treatment outcome. Implementing this strategy could help meet the Ethiopian Sustainable Development Goal targets. PMID:29209537

Planck 2015 results: II. Low Frequency Instrument data processings

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ade, P. A. R.; Aghanim, N.; Ashdown, M.

In this paper, we present an updated description of the Planck Low Frequency Instrument (LFI) data processing pipeline, associated with the 2015 data release. We point out the places where our results and methods have remained unchanged since the 2013 paper and we highlight the changes made for the 2015 release, describing the products (especially timelines) and the ways in which they were obtained. We demonstrate that the pipeline is self-consistent (principally based on simulations) and report all null tests. For the first time, we present LFI maps in Stokes Q and U polarization. Finally, we refer to other relatedmore » papers where more detailed descriptions of the LFI data processing pipeline may be found if needed.« less

Planck 2015 results: II. Low Frequency Instrument data processings

DOE PAGES

Ade, P. A. R.; Aghanim, N.; Ashdown, M.; ...

2016-09-20

In this paper, we present an updated description of the Planck Low Frequency Instrument (LFI) data processing pipeline, associated with the 2015 data release. We point out the places where our results and methods have remained unchanged since the 2013 paper and we highlight the changes made for the 2015 release, describing the products (especially timelines) and the ways in which they were obtained. We demonstrate that the pipeline is self-consistent (principally based on simulations) and report all null tests. For the first time, we present LFI maps in Stokes Q and U polarization. Finally, we refer to other relatedmore » papers where more detailed descriptions of the LFI data processing pipeline may be found if needed.« less

The ASK1 gene regulates B function gene expression in cooperation with UFO and LEAFY in Arabidopsis.

PubMed

Zhao, D; Yu, Q; Chen, M; Ma, H

2001-07-01

The Arabidopsis floral regulatory genes APETALA3 (AP3) and PISTILLATA (PI) are required for the B function according to the ABC model for floral organ identity. AP3 and PI expression are positively regulated by the LEAFY (LFY) and UNUSUAL FLORAL ORGANS (UFO) genes. UFO encodes an F-box protein, and we have shown previously that UFO genetically interacts with the ASK1 gene encoding a SKP1 homologue; both the F-box containing protein and SKP1 are subunits of ubiquitin ligases. We show here that the ask1-1 mutation can enhance the floral phenotypes of weak lfy and ap3 mutants; therefore, like UFO, ASK1 also interacts with LFY and AP3 genetically. Furthermore, our results from RNA in situ hybridizations indicate that ASK1 regulates early AP3 and PI expression. These results support the idea that UFO and ASK1 together positively regulate AP3 and PI expression. We propose that the UFO and ASK1 proteins are components of a ubiquitin ligase that mediates the proteolysis of a repressor of AP3 and PI expression. Our genetic studies also indicate that ASK1 and UFO play a role in regulating the number of floral organ primordia, and we discuss possible mechanisms for such a regulation.

Type Safe Extensible Programming

NASA Astrophysics Data System (ADS)

Chae, Wonseok

2009-10-01

Software products evolve over time. Sometimes they evolve by adding new features, and sometimes by either fixing bugs or replacing outdated implementations with new ones. When software engineers fail to anticipate such evolution during development, they will eventually be forced to re-architect or re-build from scratch. Therefore, it has been common practice to prepare for changes so that software products are extensible over their lifetimes. However, making software extensible is challenging because it is difficult to anticipate successive changes and to provide adequate abstraction mechanisms over potential changes. Such extensibility mechanisms, furthermore, should not compromise any existing functionality during extension. Software engineers would benefit from a tool that provides a way to add extensions in a reliable way. It is natural to expect programming languages to serve this role. Extensible programming is one effort to address these issues. In this thesis, we present type safe extensible programming using the MLPolyR language. MLPolyR is an ML-like functional language whose type system provides type-safe extensibility mechanisms at several levels. After presenting the language, we will show how these extensibility mechanisms can be put to good use in the context of product line engineering. Product line engineering is an emerging software engineering paradigm that aims to manage variations, which originate from successive changes in software.

Correlation between extension-block K-wire insertion angle and postoperative extension loss in mallet finger fracture.

PubMed

Lee, S K; Kim, Y H; Moon, K H; Choy, W S

2018-02-01

Extension-block pinning represents a simple and reliable surgical technique. Although this procedure is commonly performed successfully, some patients develop postoperative extension loss. To date, the relationship between extension-block Kirschner wire (K-wire) insertion angle and postoperative extension loss in mallet finger fracture remains unclear. We aimed to clarify this relationship and further evaluate how various operative and non-operative factors affect postoperative extension loss after extension-block pinning for mallet finger fracture. A retrospective study was conducted to investigate a relationship between extension block K-wire insertion angle and postoperative extension loss. The inclusion criteria were: (1) a dorsal intra-articular fracture fragment involving 30% of the base of the distal phalanx with or without volar subluxation of the distal phalanx; and (2) <3 weeks delay from the injury without treatment. Extension-block K-wire insertion angle and fixation angle of the distal interphalangeal (DIP) joint were assessed using lateral radiograph at immediate postoperative time. Postoperative extension loss was assessed by using lateral radiograph at latest follow-up. Extension-block K-wire insertion angle was defined as the acute angle between extension block K-wire and longitudinal axis of middle phalangeal head. DIP joint fixation angle was defined as the acute angle between the distal phalanx and middle phalanx longitudinal axes. Seventy-five patients were included. The correlation analysis revealed that extension-block K-wire insertion angle had a negative correlation with postoperative extension loss, whereas fracture size and time to operation had a positive correlation (correlation coefficient for extension block K-wire angle: -0.66, facture size: +0.67, time to operation: +0.60). When stratifying patients in terms of negative and positive fixation angle of the DIP joint, the independent t-test showed that mean postoperative extension

Examining Extension's Capacity in Community Resource and Economic Development: Viewpoints of Extension Administrators on the Role of Community Resource and Economic Development in the Extension Portfolio

ERIC Educational Resources Information Center

Urbanowitz, Seth C.; Wilcox, Michael D., Jr.

2013-01-01

The survey-based research reported here offers insights on community, resource, and economic development (CRED) Extension programming at the national and regional level. The results present a national picture of CRED programming, research, and potential future programming opportunities that Extension could capitalize on. The research shows that…

Utilization of a lateral flow colloidal gold immunoassay strip based on surface-enhanced Raman spectroscopy for ultrasensitive detection of antibiotics in milk

NASA Astrophysics Data System (ADS)

Shi, Qiaoqiao; Huang, Jie; Sun, Yaning; Yin, Mengqi; Hu, Mei; Hu, Xiaofei; Zhang, Zhijun; Zhang, Gaiping

2018-05-01

An ultrasensitive method for the detection of antibiotics in milk is developed based on inexpensive, simple, rapid and portable lateral flow immunoassay (LFI) strip, in combination with high sensitivity surface-enhanced Raman spectroscopy (SERS). In our strategy, an immunoprobe was prepared from colloidal gold (AuNPs) conjugated with both a monoclonal antibody against neomycin (NEO-mAb) and a Raman probe molecule 4-aminothiophenol (PATP). The competitive interaction with immunoprobe between free NEO and the coated antigen (NEO-OVA) resulted in the change of the amount of the immobilized immunoprobe on the paper substrate. The LFI procedure was completed within 15 min. The Raman intensity of PATP on the test line of the LFI strip was measured for the quantitative determination of NEO. The IC50 and the limit of detection (LOD) of this assay are 0.04 ng/mL and 0.216 pg/mL of NEO, respectively. There is no cross-reactivity (CR) of the assay with other compounds, showing high specificity of the assay. The recoveries for milk samples with added NEO are in the range of 89.7%-105.6% with the relative standard deviations (RSD) of 2.4%-5.3% (n = 3). The result reveals that this method possesses high specificity, sensitivity, reproducibility and stability, and can be used to detect a variety of antibiotic residues in milk samples.

Spread of extensively resistant VIM-2-positive ST235 Pseudomonas aeruginosa in Belarus, Kazakhstan, and Russia: a longitudinal epidemiological and clinical study.

PubMed

Edelstein, Mikhail V; Skleenova, Elena N; Shevchenko, Oksana V; D'souza, Jimson W; Tapalski, Dmitry V; Azizov, Ilya S; Sukhorukova, Marina V; Pavlukov, Roman A; Kozlov, Roman S; Toleman, Mark A; Walsh, Timothy R

2013-10-01

Multidrug-resistant and extensively-drug-resistant Pseudomonas aeruginosa are increasing therapeutic challenges worldwide. We did a longitudinal epidemiological and clinical study of extensively-drug-resistant P aeruginosa in Belarus, Kazakhstan, and Russia. The study was done in three prospectively defined phases: Jan 1, 2002-Dec 31, 2004; Jan 1, 2006-Dec 31, 2007; and Jan 1, 2008-Dec 31, 2010. The first two phases were in Russia only. All consecutive, non-duplicate, nosocomial isolates and case report forms were sent to the coordinating centre (Institute of Antimicrobial Chemotherapy, Smolensk, Russia), where species reidentification, susceptibility testing, and molecular typing of isolates were done. We did susceptibility testing by agar dilution. The presence of metallo-β-lactamase (MBL) genes was established by PCR and sequencing, and class 1 integrons containing MBL gene cassettes were analysed by the PCR restriction fragment length polymorphism approach. Strain relatedness was analysed by multiple loci variable-number tandem-repeat (VNTR) analysis (at six VNTR loci) and multilocus sequence typing. In 2002-04, 628 of 1053 P aeruginosa isolates were insusceptible to carbapenems and 47 (4.5%) possessed MBLs. In 2006-07, 584 of 787 isolates were insusceptible to carbapenems and 160 (20.3%) possessed MBLs. In 2008-10, 1238 of 1643 Russian P aeruginosa isolates were insusceptible to carbapenems and 471 (28.7%) possessed MBLs. Additionally, the 32 P aeruginosa isolates from Belarus and Kazakhstan were all carbapenem insusceptible and all possessed MBLs. More than 96% of MBL-positive P aeruginosa isolates were resistant to all antibiotics except colistin (ie, extensively drug resistant), and, in 2010, 5·9% were resistant to colistin. 685 (96.5%) of 710 MBL-positive P aeruginosa belonged to ST235. bla(VIM-2) genes were detected in 707 (99.6%) of 710 MBL-positive isolates. Extensively-drug-resistant ST235 P aeruginosa has rapidly spread throughout Russia and into

ULTRAPETALA1 and LEAFY pathways function independently in specifying identity and determinacy at the Arabidopsis floral meristem.

PubMed

Engelhorn, Julia; Moreau, Fanny; Fletcher, Jennifer C; Carles, Cristel C

2014-11-01

The morphological variability of the flower in angiosperms, combined with its relatively simple structure, makes it an excellent model to study cell specification and the establishment of morphogenetic patterns. Flowers are the products of floral meristems, which are determinate structures that generate four different types of floral organs before terminating. The precise organization of the flower in whorls, each defined by the identity and number of organs it contains, is controlled by a multi-layered network involving numerous transcriptional regulators. In particular, the AGAMOUS (AG) MADS domain-containing transcription factor plays a major role in controlling floral determinacy in Arabidopsis thaliana in addition to specifying reproductive organ identity. This study aims to characterize the genetic interactions between the ULTRAPETALA1 (ULT1) and LEAFY (LFY) transcriptional regulators during flower morphogenesis, with a focus on AG regulation. Genetic and molecular approaches were used to address the question of redundancy and reciprocal interdependency for the establishment of flower meristem initiation, identity and termination. In particular, the effects of loss of both ULT1 and LFY function were determined by analysing flower developmental phenotypes of double-mutant plants. The dependency of each factor on the other for activating developmental genes was also investigated in gain-of-function experiments. The ULT1 and LFY pathways, while both activating AG expression in the centre of the flower meristem, functioned independently in floral meristem determinacy. Ectopic transcriptional activation by ULT1 of AG and AP3, another gene encoding a MADS domain-containing flower architect, did not depend on LFY function. Similarly, LFY did not require ULT1 function to ectopically determine floral fate. The results indicate that the ULT1 and LFY pathways act separately in regulating identity and determinacy at the floral meristem. In particular, they independently

simulation of the DNA force-extension curve

NASA Astrophysics Data System (ADS)

Shinaberry, Gregory; Mikhaylov, Ivan; Balaeff, Alexander

A molecular dynamics simulation study of the force-extension curve of double-stranded DNA is presented. Extended simulations of the DNA at multiple points along the force-extension curve are conducted with DNA end-to-end length constrained at each point. The calculated force-extension curve qualitatively reproduces the experimental one. The DNA conformational ensemble at each extension shows that the famous plateau of the force-extension curve results from B-DNA melting, whereas the formation of the earlier-predicted novel DNA conformation called 'zip-DNA' takes place at extensions past the plateau. An extensive analysis of the DNA conformational ensemble in terms of base configuration, backbone configuration, solvent interaction energy, etc., is conducted in order to elucidate the physical origin of DNA elasticity and the main interactions responsible for the shape of the force-extension curve.

A link between LEAFY and B-gene homologues in Welwitschia mirabilis sheds light on ancestral mechanisms prefiguring floral development.

PubMed

Moyroud, Edwige; Monniaux, Marie; Thévenon, Emmanuel; Dumas, Renaud; Scutt, Charles P; Frohlich, Michael W; Parcy, François

2017-10-01

Flowering plants evolved from an unidentified gymnosperm ancestor. Comparison of the mechanisms controlling development in angiosperm flowers and gymnosperm cones may help to elucidate the mysterious origin of the flower. We combined gene expression studies with protein behaviour characterization in Welwitschia mirabilis to test whether the known regulatory links between LEAFY and its MADS-box gene targets, central to flower development, might also contribute to gymnosperm reproductive development. We found that WelLFY, one of two LEAFY-like genes in Welwitschia, could be an upstream regulator of the MADS-box genes APETALA3/PISTILLATA-like (B-genes). We demonstrated that, even though their DNA-binding domains are extremely similar, WelLFY and its paralogue WelNDLY exhibit distinct DNA-binding specificities, and that, unlike WelNDLY, WelLFY shares with its angiosperm orthologue the capacity to bind promoters of Welwitschia B-genes. Finally, we identified several cis-elements mediating these interactions in Welwitschia and obtained evidence that the link between LFY homologues and B-genes is also conserved in two other gymnosperms, Pinus and Picea. Although functional approaches to investigate cone development in gymnosperms are limited, our state-of-the-art biophysical techniques, coupled with expression studies, provide evidence that crucial links, central to the control of floral development, may already have existed before the appearance of flowers. © 2017 The Authors. New Phytologist © 2017 New Phytologist Trust.

Phase-Shifted Laser Feedback Interferometry

NASA Technical Reports Server (NTRS)

Ovryn, Benjie

1999-01-01

Phase-shifted, laser feedback interferometry is a new diagnostic tool developed at the NASA Lewis Research Center under the Advanced Technology Development (ATD) Program directed by NASA Headquarters Microgravity Research Division. It combines the principles of phase-shifting interferometry (PSI) and laser-feedback interferometry (LFI) to produce an instrument that can quantify both optical path length changes and sample reflectivity variations. In a homogenous medium, the optical path length between two points is the product of the index of refraction and the geometric distance between the two points. LFI differs from other forms of interferometry by using the laser as both the source and the phase detector. In LFI, coherent feedback of the incident light either reflected directly from a surface or reflected after transmission through a region of interest will modulate the output intensity of the laser. The combination of PSI and LFI has produced a robust instrument, based on a low-power helium-neon (HeNe) gas laser, with a high dynamic range that can be used to measure either static or oscillatory changes of the optical path length. Small changes in optical path length are limited by the fraction of a fringe that can be measured; we can measure nonoscillatory changes with a root mean square (rms) error of the wavelength/1000 without averaging.

A novel role of BELL1-like homeobox genes, PENNYWISE and POUND-FOOLISH, in floral patterning.

PubMed

Yu, Lifeng; Patibanda, Varun; Smith, Harley M S

2009-02-01

Flowers are determinate shoots comprised of perianth and reproductive organs displayed in a whorled phyllotactic pattern. Floral organ identity genes display region-specific expression patterns in the developing flower. In Arabidopsis, floral organ identity genes are activated by LEAFY (LFY), which functions with region-specific co-regulators, UNUSUAL FLORAL ORGANS (UFO) and WUSCHEL (WUS), to up-regulate homeotic genes in specific whorls of the flower. PENNYWISE (PNY) and POUND-FOOLISH (PNF) are redundant functioning BELL1-like homeodomain proteins that are expressed in shoot and floral meristems. During flower development, PNY functions with a co-repressor complex to down-regulate the homeotic gene, AGAMOUS (AG), in the outer whorls of the flower. However, the function of PNY as well as PNF in regulating floral organ identity in the central whorls of the flower is not known. In this report, we show that combining mutations in PNY and PNF enhance the floral patterning phenotypes of weak and strong alleles of lfy, indicating that these BELL1-like homeodomain proteins play a role in the specification of petals, stamens and carpels during flower development. Expression studies show that PNY and PNF positively regulate the homeotic genes, APETALA3 and AG, in the inner whorls of the flower. Moreover, PNY and PNF function in parallel with LFY, UFO and WUS to regulate homeotic gene expression. Since PNY and PNF interact with the KNOTTED1-like homeodomain proteins, SHOOTMERISTEMLESS (STM) and KNOTTED-LIKE from ARABIDOPSIS THALIANA2 (KNAT2) that regulate floral development, we propose that PNY/PNF-STM and PNY/PNF-KNAT2 complexes function in the inner whorls to regulate flower patterning events.

An Activated Form of UFO Alters Leaf Development and Produces Ectopic Floral and Inflorescence Meristems

PubMed Central

Risseeuw, Eddy; Venglat, Prakash; Xiang, Daoquan; Komendant, Kristina; Daskalchuk, Tim; Babic, Vivijan; Crosby, William; Datla, Raju

2013-01-01

Plants are unique in their ability to continuously produce new meristems and organ primordia. In Arabidopsis, the transcription factor LEAFY (LFY) functions as a master regulator of a gene network that is important for floral meristem and organ specification. UNUSUAL FLORAL ORGANS (UFO) is a co-activator of LEAFY and is required for proper activation of APETALA3 in the floral meristem during the specification of stamens and petals. The ufo mutants display defects in other parts of the flower and the inflorescence, suggestive of additional roles. Here we show that the normal determinacy of the developing Arabidopsis leaves is affected by the expression of a gain-of-function UFO fusion protein with the VP16 transcriptional activator domain. In these lines, the rosette and cauline leaf primordia exhibit reiterated serration, and upon flowering produce ectopic meristems that develop into flowers, bract leaves and inflorescences. These striking phenotypes reveal that developing leaves maintain the competency to initiate flower and inflorescence programs. Furthermore, the gain-of-function phenotypes are dependent on LFY and the SEPALLATA (SEP) MADS-box transcription factors, indicative of their functional interactions with UFO. The findings of this study also suggest that UFO promotes the establishment of the lateral meristems and primordia in the peripheral zone of the apical and floral meristems by enhancing the activity of LFY. These novel phenotypes along with the mutant phenotypes of UFO orthologs in other plant species suggest a broader function for UFO in plants. PMID:24376756

An activated form of UFO alters leaf development and produces ectopic floral and inflorescence meristems.

PubMed

Risseeuw, Eddy; Venglat, Prakash; Xiang, Daoquan; Komendant, Kristina; Daskalchuk, Tim; Babic, Vivijan; Crosby, William; Datla, Raju

2013-01-01

Plants are unique in their ability to continuously produce new meristems and organ primordia. In Arabidopsis, the transcription factor LEAFY (LFY) functions as a master regulator of a gene network that is important for floral meristem and organ specification. UNUSUAL FLORAL ORGANS (UFO) is a co-activator of LEAFY and is required for proper activation of APETALA3 in the floral meristem during the specification of stamens and petals. The ufo mutants display defects in other parts of the flower and the inflorescence, suggestive of additional roles. Here we show that the normal determinacy of the developing Arabidopsis leaves is affected by the expression of a gain-of-function UFO fusion protein with the VP16 transcriptional activator domain. In these lines, the rosette and cauline leaf primordia exhibit reiterated serration, and upon flowering produce ectopic meristems that develop into flowers, bract leaves and inflorescences. These striking phenotypes reveal that developing leaves maintain the competency to initiate flower and inflorescence programs. Furthermore, the gain-of-function phenotypes are dependent on LFY and the SEPALLATA (SEP) MADS-box transcription factors, indicative of their functional interactions with UFO. The findings of this study also suggest that UFO promotes the establishment of the lateral meristems and primordia in the peripheral zone of the apical and floral meristems by enhancing the activity of LFY. These novel phenotypes along with the mutant phenotypes of UFO orthologs in other plant species suggest a broader function for UFO in plants.

Differences in liver functionality indexes in peripartal dairy cows fed rumen-protected methionine or choline are associated with performance, oxidative stress status, and plasma amino acid profiles.

PubMed

Zhou, Z; Trevisi, E; Luchini, D N; Loor, J J

2017-08-01

The liver functionality index (LFI) represents an assessment of transition cow metabolic health by measuring changes in biomarkers associated with liver plasma protein synthesis (albumin), lipoprotein synthesis (cholesterol), and heme catabolism (bilirubin). The present analysis was conducted to determine the role of peripartal rumen-protected Met or choline (CHOL) supplementation on LFI groupings, and to assess relationships with performance, inflammation, oxidative stress status, and plasma AA profiles. A cohort of 40 multiparous Holstein cows that were part of a randomized complete block design with 2 × 2 factorial arrangement of Met (Smartamine M, Adisseo NA, Alpharetta, GA) and CHOL (ReaShure, Balchem Inc., New Hampton, NY) level (with or without) were used. From -21 d to calving, cows received the same close-up diet and were assigned randomly to each treatment. From calving to 30 d, cows were on the same postpartal diet and continued to receive the same treatments until 30 d. Addition of Met was adjusted daily at 0.08% dry matter of diet and CHOL was fed at 60 g/cow per day. Liver (-10, 7, 20, and 30 d) and blood (-10, 4, 8, 20, and 30 d) samples were harvested for biomarker analyses. Cows were ranked retrospectively and assigned to low (LLFI, LFI <0) and high (HLFI, LFI >0) LFI groups regardless of Met or CHOL supplementation. Compared with cows in LLFI, close-up and lactation DMI, milk yield, milk fat yield, and milk protein yield were greater in HLFI cows. As expected, cows in LLFI had lower plasma cholesterol and albumin but greater bilirubin concentrations around parturition. Plasma haptoglobin concentration was also lower in HLFI cows, but plasma paraoxonase and hepatic total and reduced hepatic glutathione concentrations were greater. Although higher concentrations of His, Met, and Trp, as well as a tendency for greater Ile, were observed in HLFI cows, overall essential AA concentrations did not differ with LFI status. In contrast, overall

Extension of Structure-Reactivity Correlations for the Hydrogen Abstraction Reaction by Bromine Atom and Comparison to Chlorine Atom and Hydroxyl Radical.

PubMed

Poutsma, Marvin L

2016-01-21

Recently we presented structure-reactivity correlations for the gas-phase ambient-temperature rate constants for hydrogen abstraction from sp(3)-hybridized carbon by chlorine atom and hydroxyl radical (Cl•/HO• + HCR3 → HCl/HOH + •CR3); the reaction enthalpy effect was represented by the independent variable ΔrH and the "polar effect" by the independent variables F and R, the Hammett constants for field/inductive and resonance effects. Both these reactions are predominantly exothermic and have early transition states. Here, we present a parallel treatment for Br• whose reaction is significantly endothermic with a correspondingly late transition state. Despite lower expectations because the available database is less extensive and much more scattered and because long temperature extrapolations are often required, the resulting least-squares fit (log k298,Br = -0.147 ΔrH - 4.32 ΣF - 4.28 ΣR - 12.38 with r(2) = 0.92) was modestly successful and useful for initial predictions. The coefficient of ΔrH was ∼4-fold greater, indicative of the change from an early to a late transition state; meanwhile the sizable coefficients of ΣF and ΣR indicate the persistence of the "polar effect". Although the mean unsigned deviation of 0.79 log k298 units is rather large, it must be considered in the context of a total span of over 15 log units in the data set. The major outliers are briefly discussed.

40 CFR 231.8 - Extension of time.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Extension of time. 231.8 Section 231.8 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING SECTION 404(c) PROCEDURES § 231.8 Extension of time. The Administrator or the Regional Administrator may, upon a showing of good...

40 CFR 231.8 - Extension of time.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Extension of time. 231.8 Section 231.8 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING SECTION 404(c) PROCEDURES § 231.8 Extension of time. The Administrator or the Regional Administrator may, upon a showing of good...

Development of Prototype Filovirus Recombinant Antigen Immunoassays

PubMed Central

Boisen, Matt L.; Oottamasathien, Darin; Jones, Abigail B.; Millett, Molly M.; Nelson, Diana S.; Bornholdt, Zachary A.; Fusco, Marnie L.; Abelson, Dafna M.; Oda, Shun-ichiro; Hartnett, Jessica N.; Rowland, Megan M.; Heinrich, Megan L.; Akdag, Marjan; Goba, Augustine; Momoh, Mambu; Fullah, Mohammed; Baimba, Francis; Gbakie, Michael; Safa, Sadiki; Fonnie, Richard; Kanneh, Lansana; Cross, Robert W.; Geisbert, Joan B.; Geisbert, Thomas W.; Kulakosky, Peter C.; Grant, Donald S.; Shaffer, Jeffery G.; Schieffelin, John S.; Wilson, Russell B.; Saphire, Erica Ollmann; Branco, Luis M.; Garry, Robert F.; Khan, S. Humarr; Pitts, Kelly R.

2015-01-01

Background. Throughout the 2014–2015 Ebola outbreak in West Africa, major gaps were exposed in the availability of validated rapid diagnostic platforms, protective vaccines, and effective therapeutic agents. These gaps potentiated the development of prototype rapid lateral flow immunodiagnostic (LFI) assays that are true point-of-contact platforms, for the detection of active Ebola infections in small blood samples. Methods. Recombinant Ebola and Marburg virus matrix VP40 and glycoprotein (GP) antigens were used to derive a panel of monoclonal and polyclonal antibodies. Antibodies were tested using a multivariate approach to identify antibody-antigen combinations suitable for enzyme-linked immunosorbent assay (ELISA) and LFI assay development. Results. Polyclonal antibodies generated in goats were superior reagents for capture and detection of recombinant VP40 in test sample matrices. These antibodies were optimized for use in antigen-capture ELISA and LFI assay platforms. Prototype immunoglobulin M (IgM)/immunoglobulin G (IgG) ELISAs were similarly developed that specifically detect Ebola virus–specific antibodies in the serum of experimentally infected nonhuman primates and in blood samples obtained from patients with Ebola from Sierra Leone. Conclusions. The prototype recombinant Ebola LFI assays developed in these studies have sensitivities that are useful for clinical diagnosis of acute ebolavirus infections. The antigen-capture and IgM/IgG ELISAs provide additional confirmatory assay platforms for detecting VP40 and other ebolavirus-specific immunoglobulins. PMID:26232440

Turning an Extension Aide into an Extension Agent

ERIC Educational Resources Information Center

Seevers, Brenda; Dormody, Thomas J.

2010-01-01

For any organization to remain sustainable, a renewable source of faculty and staff needs to be available. The Extension Internship Program for Juniors and Seniors in High School is a new tool for recruiting and developing new Extension agents. Students get "hands on" experience working in an Extension office and earn college credit…

A Conceptual Framework for Determining Training Needs of Extension Agents Applied to Dairy Science. The Findings from Extension Studies.

ERIC Educational Resources Information Center

Verma, Satish

A summary of an Extension Education dissertation on a study to develop a framework of curriculum and learning theory features, to determine needs of Extension agents, and to show its application to dairy science is presented. Tyler's rationale for deriving educational objectives (curriculum theory) and Bloom's taxonomy of cognitive behavior…

KSC-2015-1238

NASA Image and Video Library

2015-01-28

VANDENBERG AIR FORCE BASE, Calif. – The launch gantry is rolled back to reveal the United Launch Alliance Delta II rocket with the Soil Moisture Active Passive, or SMAP, satellite aboard, at Space Launch Complex 2 on Vandenberg Air Force Base in California. SMAP is a remote sensing mission designed to measure and map the Earth's soil moisture distribution and freeze/thaw stat with unprecedented accuracy, resolution and coverage. SMAP will provide global measurements of soil moisture and its freeze/thaw state. These measurements will be used to enhance understanding of processes that link the water, energy and carbon cycles, and to extend the capabilities of weather and climate prediction models. SMAP data also will be used to quantify net carbon flux in boreal landscapes and to develop improved flood prediction and drought monitoring capabilities. Launch is scheduled for Jan. 29, 2015. To learn more about SMAP, visit http://www.nasa.gov/smap. Photo credit: NASA/Randy Beaudoin

KSC-2013-1238

NASA Image and Video Library

2013-01-29

CAPE CANAVERAL, Fla. -- At Cape Canaveral Air Force Station's Space Launch Complex 41, the United Launch Alliance Atlas V rocket set to carry NASA's Tracking and Data Relay Satellite, TDRS-K, stands at the launch pad after leaving the Vertical Integration Facility. Liftoff for the TDRS-K is planned for Jan. 30, 2013. The TDRS-K spacecraft is part of the next-generation series in the Tracking and Data Relay Satellite System, a constellation of space-based communication satellites providing tracking, telemetry, command and high-bandwidth data return services. For more information, visit http://www.nasa.gov/mission_pages/tdrs/index.html Photo credit: NASA/Kim Shiflett

Motor units in vastus lateralis and in different vastus medialis regions show different firing properties during low-level, isometric knee extension contraction.

PubMed

de Souza, Leonardo Mendes Leal; Cabral, Hélio Veiga; de Oliveira, Liliam Fernandes; Vieira, Taian Martins

2018-04-01

Architectural differences along vastus medialis (VM) and between VM and vastus lateralis (VL) are considered functionally important for the patellar tracking, knee joint stability and knee joint extension. Whether these functional differences are associated with a differential activity of motor units between VM and VL is however unknown. In the present study, we, therefore, investigate neuroanatomical differences in the activity of motor units detected proximo-distally from VM and from the VL muscle. Nine healthy volunteers performed low-level isometric knee extension contractions (20% of their maximum voluntary contraction) following a trapezoidal trajectory. Surface electromyograms (EMGs) were recorded from VM proximal and distal regions and from VL using three linear adhesive arrays of eight electrodes. The firing rate and recruitment threshold of motor units decomposed from EMGs were then compared among muscle regions. Results show that VL motor units reached lower mean firing rates in comparison with VM motor units, regardless of their position within VM (P < .040). No significant differences in firing rate were found between proximal and distal, VM motor units (P = .997). Furthermore, no significant differences in the recruitment threshold were observed for all motor units analysed (P = .108). Our findings possibly suggest the greater potential of VL to generate force, due to its fibres arrangement, may account for the lower discharge rate observed for VL then either proximally or distally detected motor units in VM. Additionally, the present study opens new perspectives on the importance of considering muscle architecture in investigations of the neural aspects of motor behaviour. Copyright © 2017 Elsevier B.V. All rights reserved.

1. EAST AND SOUTH SIDES OF STATION, SHOWING (LEFT BACKGROUND ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. EAST AND SOUTH SIDES OF STATION, SHOWING (LEFT BACKGROUND TO CENTER FOREGROUND) SOUTH CANOPY, OPEN CONCOURSE ROOF, AND CONCOURSE ROOF EXTENSION (SMALL BUILDING UNDER CONCOURSE ROOF IS TEMPORARY AMTRAK STATION) - Pennsylvania Railroad Station, Open Concourse & Concourse Roof Extension, 1101 Liberty Avenue, Pittsburgh, Allegheny County, PA

Development of a model based on biochemical, real‑time tissue elastography and ultrasound data for the staging of liver fibrosis and cirrhosis in patients with chronic hepatitis B.

PubMed

Xu, Shi-Hao; Li, Qiao; Hu, Yuan-Ping; Ying, Li

2016-10-01

The liver fibrosis index (LFI), based on real‑time tissue elastography (RTE), is a method currently used to assess liver fibrosis. However, this method may not consistently distinguish between the different stages of fibrosis, which limits its accuracy. The aim of the present study was to develop novel models based on biochemical, RTE and ultrasound data for predicting significant liver fibrosis and cirrhosis. A total of 85 consecutive patients with chronic hepatitis B (CHB) were prospectively enrolled and underwent a liver biopsy and RTE. The parameters for predicting significant fibrosis and cirrhosis were determined by conducting multivariate analyses. The splenoportal index (SPI; P=0.002) and LFI (P=0.023) were confirmed as independent predictors of significant fibrosis. Using multivariate analyses for identifying parameters that predict cirrhosis, significant differences in γ‑glutamyl transferase (GGT; P=0.049), SPI (P=0.002) and LFI (P=0.001) were observed. Based on these observations, the novel model LFI‑SPI score (LSPS) was developed to predict the occurrence of significant liver fibrosis, with an area under receiver operating characteristic curves (AUROC) of 0.87. The diagnostic accuracy of the LSPS model was superior to that of the LFI (AUROC=0.76; P=0.0109), aspartate aminotransferase‑to‑platelet ratio index (APRI; AUROC=0.64; P=0.0031), fibrosis‑4 index (FIB‑4; AUROC=0.67; P=0.0044) and FibroScan (AUROC=0.68; P=0.0021) models. In addition, the LFI‑SPI‑GGT score (LSPGS) was developed for the purposes of predicting liver cirrhosis, demonstrating an AUROC value of 0.93. The accuracy of LSPGS was similar to that of FibroScan (AUROC=0.85; P=0.134), but was superior to LFI (AUROC=0.81; P=0.0113), APRI (AUROC=0.67; P<0.0001) and FIB‑4 (AUROC=0.719; P=0.0005). In conclusion, the results of the present study suggest that the use of LSPS and LSPGS may complement current methods of diagnosing significant liver fibrosis and cirrhosis in

Application of Phase Shifted, Laser Feedback Interferometry to Fluid Physics

NASA Technical Reports Server (NTRS)

Ovryn, Ben; Eppell, Steven J.; Andrews, James H.; Khaydarov, John

1996-01-01

We have combined the principles of phase-shifting interferometry (PSI) and laser-feedback interferometry (LFI) to produce a new instrument that can measure both optical path length (OPL) changes and discern sample reflectivity variations. In LFI, coherent feedback of the incident light either reflected directly from a surface or reflected after transmission through a region of interest will modulate the output intensity of the laser. LFI can yield a high signal-to-noise ratio even for low reflectivity samples. By combining PSI and LFI, we have produced a robust instrument, based upon a HeNe laser, with high dynamic range that can be used to measure either static (dc) or oscillatory changes along the optical path. As with other forms of interferometry, large changes in OPL require phase unwrapping. Conversely, small phase changes are limited by the fraction of a fringe that can be measured. We introduce the phase shifts with an electro-optic modulator (EOM) and use either the Carre or Hariharan algorithms to determine the phase and visibility. We have determined the accuracy and precision of our technique by measuring both the bending of a cantilevered piezoelectric bimorph and linear ramps to the EOM. Using PSI, sub-nanometer displacements can be measured. We have combined our interferometer with a commercial microscope and scanning piezoelectric stage and have measured the variation in OPL and visibility for drops of PDMS (silicone oil) on coated single crystal silicon. Our measurement of the static contact angle agrees with the value of 68 deg stated in the literature.

13. Interior detail, Blacksmith Shop, showing a portion of the ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

13. Interior detail, Blacksmith Shop, showing a portion of the original overhead belt drive system that powered machine tools in the adjacent Machine Shop, Roundhouse Machine Shop Extension, Southern Pacific Railroad Carlin Shops, view to west, 135mm lens. - Southern Pacific Railroad, Carlin Shops, Roundhouse Machine Shop Extension, Foot of Sixth Street, Carlin, Elko County, NV

Extension of structure-reactivity correlations for the hydrogen abstraction reaction by bromine atom and comparison to chlorine atom and hydroxyl radical

DOE PAGES

Poutsma, Marvin L.

2015-12-14

Recently we presented structure-reactivity correlations for the gas-phase ambient-temperature rate constants for hydrogen abstraction from sp 3-hybridized carbon by chlorine atom and hydroxyl radical (Cl•/HO• + HCR 3 → HCl/HOH + •CR 3); the reaction enthalpy effect was represented by the independent variable Δ rH and the polar effect by the independent variables F and R, the Hammett constants for field/inductive and resonance effects. Both these reactions are predominantly exothermic and have early transition states. Here we present a parallel treatment for Br• whose reaction is significantly endothermic with a correspondingly late transition state. In spite of lower expectations becausemore » the available data base is less extensive and much more scattered and because long temperature extrapolations are often required, the resulting least-squares fit (log k 298,Br = –0.147 Δ rH –4.32 ΣF –4.28 ΣR –12.38 with r 2 = 0.92) was modestly successful and useful for initial predictions. The coefficient of Δ rH was ~4-fold greater, indicative of the change from an early to a late transition state; meanwhile the sizable coefficients of ΣF and ΣR indicate the persistence of the polar effect. Although the mean unsigned deviation of 0.79 log k 298 units is rather large, it must be considered in the context of a total span of over 15 log units in the data set. Lastly, the major outliers are briefly discussed.« less

Elbow arthroscopy: valgus extension overload.

PubMed

Ahmad, Christopher S; Conway, John E

2011-01-01

Valgus torque combined with deceleration produces high compression and shear forces acting on the posteromedial olecranon and the posteromedial trochlea. This valgus extension overload process may cause posteromedial trochlea chondromalacia, chondral flap formation, osteochondrosis, subchondral erosion, a subchondral insufficiency fracture, and marginal exostosis formation. Olecranon pathologies include proximal stress reaction, a posteromedial tip stress fracture, a transverse proximal process stress fracture, exostosis formation, exostosis fragmentation, and intra-articular loose bodies. Symptoms include posteromedial elbow pain during the deceleration phase of the throwing motion. The extension impingement test reproduces posterior or posteromedial pain similar to that experienced while throwing. Special radiographic techniques and CT scans can show loose bodies and osteophyte fragmentation. Surgical treatment is indicated when symptoms persist despite nonsurgical management. Based on clinical and basic science research, all patients with valgus extension overload should be comprehensively evaluated for medial ulnar collateral ligament insufficiency. Surgical treatment is limited to the resection of osteophytes only; normal olecranon should not be resected.

Initiation of diapirism by regional extension

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jackson, M.P.A.; Vendeville, B.C.

Initiation of diapirism is one of the least understood aspects of salt tectonics. Sedimentary differential loading is a favorite explanation, but special conditions such as focused sedimentation are needed to trigger diapirism by differential loading. Compilation of published data from 18 of the world's salt-diapir provinces shows that salt upwelling is consistently linked in time with regional extension, whether thin-skinned or thick-skinned. Extended salt basins typically develop salt structures, whereas nonextended basins typically do not. In some basins containing thick salt (SW Iran), diapirism was delayed as long as 400 Ma until the basin was regionally extended. In other saltmore » provinces (Maritime Alps), episodic growth of salt diapirs correlates with episodic regional extension during opening of the Neo-Tethys and Atlantic Oceans. Once initiated, salt diapirism can continue after regional extension is succeeded by contraction or quiescence. Thus even in salt basins overprinted by inversion or orogenic contraction (Morocco, Lusitania, Basque-Cantabrian, North Sea), the diapirs were initiated during extension on divergent continental margins or in intracontinental rifts. This observed temporal link between extension and diapirism is consistent with physical and numerical modeling, which demonstrates that extensional faulting of the overburden directly causes diapirism whether the salt was deposited before, during, or after rifting. Where the overburden is thinned by extension, pressurized salt wells up in response to the shifting positions of fault blocks.« less

Phylogenetic Characterizations of Highly Mutated EV-B106 Recombinants Showing Extensive Genetic Exchanges with Other EV-B in Xinjiang, China.

PubMed

Song, Yang; Zhang, Yong; Fan, Qin; Cui, Hui; Yan, Dongmei; Zhu, Shuangli; Tang, Haishu; Sun, Qiang; Wang, Dongyan; Xu, Wenbo

2017-02-23

Human enterovirus B106 (EV-B106) is a new member of the enterovirus B species. To date, only three nucleotide sequences of EV-B106 have been published, and only one full-length genome sequence (the Yunnan strain 148/YN/CHN/12) is available in the GenBank database. In this study, we conducted phylogenetic characterisation of four EV-B106 strains isolated in Xinjiang, China. Pairwise comparisons of the nucleotide sequences and the deduced amino acid sequences revealed that the four Xinjiang EV-B106 strains had only 80.5-80.8% nucleotide identity and 95.4-97.3% amino acid identity with the Yunnan EV-B106 strain, indicating high mutagenicity. Similarity plots and bootscanning analyses revealed that frequent intertypic recombination occurred in all four Xinjiang EV-B106 strains in the non-structural region. These four strains may share a donor sequence with the EV-B85 strain, which circulated in Xinjiang in 2011, indicating extensive genetic exchanges between these strains. All Xinjiang EV-B106 strains were temperature-sensitive. An antibody seroprevalence study against EV-B106 in two Xinjiang prefectures also showed low titres of neutralizing antibodies, suggesting limited exposure and transmission in the population. This study contributes the whole genome sequences of EV-B106 to the GenBank database and provides valuable information regarding the molecular epidemiology of EV-B106 in China.

Agricultural extension and mass media.

PubMed

Perraton, H

1983-12-01

To learn more about the use of the mass media for agricultural extension, the World Bank has considered the efforts of 2 units: INADES-formation in West Africa and the Extension Aids Branch of Malawi. The INADES-formation study focuses on Cameroon but also considers work in Rwanda and the Ivory Coast. Some general conclusions emerge from a comparison of the 2 organizations. Malawi operates an extension service which reaches farmers through extension agents, through farmer training centers, and through mass media. The Extension Aids Branch (EAB) has responsibility for its media work and broadcasts 4 1/2 hours of radio each week. Its 6 regular radio programs include a general program which interviews farmers, a music request program in which the music is interspersed with farming advice, a farming family serial, and a daily broadcast of agricultural news and information. The 17 cinema vans show some agricultural films, made by EAB, some entertainment films, and some government information films from departments other than the ministry of agriculture. EAB also has a well-developed program of research and evaluation of its own work. INADES-formation, the training section of INADES, works towards social and economic development of the population. It teaches peasant farmers and extension agents and does this through running face-to-face seminars, by publishing a magazine, "Agripromo," and through correspondence courses. In 1978-79 INADES-formation enrolled some 4500 farmers and extension agents as students. Both of these organizations work to teach farmers better agriculture techniques, and both were created in response to the fact that agricultural extension agents cannot meet all the farmers in their area. Despite the similarity of objective, there are differences in methods and philosophy. The EAB works in a single country and uses a variety of mass media, with print playing a minor role. INADES-formation is an international and nongovernmental organization and its

Competency Modeling in Extension Education: Integrating an Academic Extension Education Model with an Extension Human Resource Management Model

ERIC Educational Resources Information Center

Scheer, Scott D.; Cochran, Graham R.; Harder, Amy; Place, Nick T.

2011-01-01

The purpose of this study was to compare and contrast an academic extension education model with an Extension human resource management model. The academic model of 19 competencies was similar across the 22 competencies of the Extension human resource management model. There were seven unique competencies for the human resource management model.…

Phylogenetic Characterizations of Highly Mutated EV-B106 Recombinants Showing Extensive Genetic Exchanges with Other EV-B in Xinjiang, China

PubMed Central

Song, Yang; Zhang, Yong; Fan, Qin; Cui, Hui; Yan, Dongmei; Zhu, Shuangli; Tang, Haishu; Sun, Qiang; Wang, Dongyan; Xu, Wenbo

2017-01-01

Human enterovirus B106 (EV-B106) is a new member of the enterovirus B species. To date, only three nucleotide sequences of EV-B106 have been published, and only one full-length genome sequence (the Yunnan strain 148/YN/CHN/12) is available in the GenBank database. In this study, we conducted phylogenetic characterisation of four EV-B106 strains isolated in Xinjiang, China. Pairwise comparisons of the nucleotide sequences and the deduced amino acid sequences revealed that the four Xinjiang EV-B106 strains had only 80.5–80.8% nucleotide identity and 95.4–97.3% amino acid identity with the Yunnan EV-B106 strain, indicating high mutagenicity. Similarity plots and bootscanning analyses revealed that frequent intertypic recombination occurred in all four Xinjiang EV-B106 strains in the non-structural region. These four strains may share a donor sequence with the EV-B85 strain, which circulated in Xinjiang in 2011, indicating extensive genetic exchanges between these strains. All Xinjiang EV-B106 strains were temperature-sensitive. An antibody seroprevalence study against EV-B106 in two Xinjiang prefectures also showed low titres of neutralizing antibodies, suggesting limited exposure and transmission in the population. This study contributes the whole genome sequences of EV-B106 to the GenBank database and provides valuable information regarding the molecular epidemiology of EV-B106 in China. PMID:28230168

An Extension of the Mean Value Theorem for Integrals

ERIC Educational Resources Information Center

Khalili, Parviz; Vasiliu, Daniel

2010-01-01

In this note we present an extension of the mean value theorem for integrals. The extension we consider is motivated by an older result (here referred as Corollary 2), which is quite classical for the literature of Mathematical Analysis or Calculus. We also show an interesting application for computing the sum of a harmonic series.

2. Oblique view of southeast elevation, Roundhouse Machine Shop Extension, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. Oblique view of southeast elevation, Roundhouse Machine Shop Extension, Southern Pacific Railroad Carlin Shops, view to northeast showing the rhythm of the fenestration and pilasters (210mm lens). - Southern Pacific Railroad, Carlin Shops, Roundhouse Machine Shop Extension, Foot of Sixth Street, Carlin, Elko County, NV

The perception and identification of facial emotions in individuals with autism spectrum disorders using the Let's Face It! Emotion Skills Battery.

PubMed

Tanaka, James W; Wolf, Julie M; Klaiman, Cheryl; Koenig, Kathleen; Cockburn, Jeffrey; Herlihy, Lauren; Brown, Carla; Stahl, Sherin S; South, Mikle; McPartland, James C; Kaiser, Martha D; Schultz, Robert T

2012-12-01

Although impaired social-emotional ability is a hallmark of autism spectrum disorder (ASD), the perceptual skills and mediating strategies contributing to the social deficits of autism are not well understood. A perceptual skill that is fundamental to effective social communication is the ability to accurately perceive and interpret facial emotions. To evaluate the expression processing of participants with ASD, we designed the Let's Face It! Emotion Skills Battery (LFI! Battery), a computer-based assessment composed of three subscales measuring verbal and perceptual skills implicated in the recognition of facial emotions. We administered the LFI! Battery to groups of participants with ASD and typically developing control (TDC) participants that were matched for age and IQ. On the Name Game labeling task, participants with ASD (N = 68) performed on par with TDC individuals (N = 66) in their ability to name the facial emotions of happy, sad, disgust and surprise and were only impaired in their ability to identify the angry expression. On the Matchmaker Expression task that measures the recognition of facial emotions across different facial identities, the ASD participants (N = 66) performed reliably worse than TDC participants (N = 67) on the emotions of happy, sad, disgust, frighten and angry. In the Parts-Wholes test of perceptual strategies of expression, the TDC participants (N = 67) displayed more holistic encoding for the eyes than the mouths in expressive faces whereas ASD participants (N = 66) exhibited the reverse pattern of holistic recognition for the mouth and analytic recognition of the eyes. In summary, findings from the LFI! Battery show that participants with ASD were able to label the basic facial emotions (with the exception of angry expression) on par with age- and IQ-matched TDC participants. However, participants with ASD were impaired in their ability to generalize facial emotions across different identities and showed a tendency to recognize

Phylogeny and Divergence Times of Gymnosperms Inferred from Single-Copy Nuclear Genes

PubMed Central

Guo, Dong-Mei; Yang, Zu-Yu; Wang, Xiao-Quan

2014-01-01

Phylogenetic reconstruction is fundamental to study evolutionary biology and historical biogeography. However, there was not a molecular phylogeny of gymnosperms represented by extensive sampling at the genus level, and most published phylogenies of this group were constructed based on cytoplasmic DNA markers and/or the multi-copy nuclear ribosomal DNA. In this study, we use LFY and NLY, two single-copy nuclear genes that originated from an ancient gene duplication in the ancestor of seed plants, to reconstruct the phylogeny and estimate divergence times of gymnosperms based on a complete sampling of extant genera. The results indicate that the combined LFY and NLY coding sequences can resolve interfamilial relationships of gymnosperms and intergeneric relationships of most families. Moreover, the addition of intron sequences can improve the resolution in Podocarpaceae but not in cycads, although divergence times of the cycad genera are similar to or longer than those of the Podocarpaceae genera. Our study strongly supports cycads as the basal-most lineage of gymnosperms rather than sister to Ginkgoaceae, and a sister relationship between Podocarpaceae and Araucariaceae and between Cephalotaxaceae-Taxaceae and Cupressaceae. In addition, intergeneric relationships of some families that were controversial, and the relationships between Taxaceae and Cephalotaxaceae and between conifers and Gnetales are discussed based on the nuclear gene evidence. The molecular dating analysis suggests that drastic extinctions occurred in the early evolution of gymnosperms, and extant coniferous genera in the Northern Hemisphere are older than those in the Southern Hemisphere on average. This study provides an evolutionary framework for future studies on gymnosperms. PMID:25222863

Development of a multiplex lateral flow strip test for foot-and-mouth disease virus detection using monoclonal antibodies.

PubMed

Yang, Ming; Caterer, Nigel R; Xu, Wanhong; Goolia, Melissa

2015-09-01

Foot-and-mouth disease (FMD) is one of the world's most highly contagious animal diseases with tremendous economic consequences. A rapid and specific test for FMD diagnosis at the site of a suspected outbreak is crucial for the implementation of control measures. This project developed a multiplex lateral flow immunochromatographic strip test (multiplex-LFI) for the rapid detection and serotyping of FMD viruses. The monoclonal antibodies (mAbs) against serotypes O, A, and Asia 1 were used as capture mAbs. The mAbs were conjugated with fluorescein, rhodamine or biotin for serotype O, A and Asia 1, respectively. The detection mAbs which consisted of a serotype-independent mAb in combination with one serotype A-specific mAb and one Asia 1-specific mAb, were each colloidal gold-conjugated. The strips used in this study contained one control line and three test lines, which corresponded to one of the three serotypes, O, A or Asia 1. The newly developed multiplex-LFI strip test specifically identified serotype O (n=46), A (n=45) and Asia 1 (n=17) in all tested field isolates. The sensitivity of this strip test was comparable to the double antibody sandwich ELISA for serotypes O and A, but lower than the ELISA for serotype Asia 1. The multiplex-LFI strip test identified all tissue suspensions from animals that were experimentally inoculated with serotypes O, A or Asia 1. FMD viruses were detected in 38% and 50% of the swab samples from the lesion areas of experimentally inoculated sheep for serotypes O and A, respectively. The capability of the multiplex-LFI strip tests to produce rapid results with high specificity for FMD viruses of multiple serotypes makes this test a valuable tool to detect FMD viruses at outbreak sites. Crown Copyright © 2015. Published by Elsevier B.V. All rights reserved.

KSC-04PD-1238

NASA Technical Reports Server (NTRS)

2004-01-01

KENNEDY SPACE CENTER, FLA. The first human journey to the surface of the Moon began at Pad A, Launch Complex 39, Kennedy Space Center, Fla., with the liftoff of Apollo 11 on a Saturn V booster at 9:32 a.m. EDT (13:32 UT) on a clear sunny Wednesday, 16 July 1969. This year NASA celebrates the 35th anniversary of that historic launch and landing. For more information and photos, go to http://nssdc.gsfc.nasa.gov/planetary/lunar/apollo_11_30th.html .

KSC-98pc1238

NASA Image and Video Library

1998-09-21

KENNEDY SPACE CENTER, FLA. -- Looking eastward, the Vehicle Assembly Building (VAB) in the Launch Complex 39 area can be seen with its new coat of paint, along with newly painted American flag and NASA logo. The improved look was finished in time to honor NASA's 40th anniversary on Oct. 1. In order to do the job, workers were suspended on platforms from the top of the 525-foot-high VAB. One of the world's largest buildings by volume, the VAB is the last stop for the Shuttle before rollout to the launch pad. Integration and stacking of the complete Space Shuttle vehicle (orbiter, two solid rocket boosters and the external tank) takes place in High Bays 1 or 3. Stretching from the side of the VAB, on the right, is the crawlerway, used to transport the Space Shuttle to the launch pad. Beyond the VAB is Banana Creek

KSC-97PC1238

NASA Image and Video Library

1997-08-13

The Advanced Composition Explorer (ACE) spacecraft is placed atop its launch vehicle at Launch Complex 17A. Scheduled for launch on a Delta II rocket from Cape Canaveral Air Station on Aug. 24, ACE will study low-energy particles of solar origin and high-energy galactic particles. The collecting power of instruments aboard ACE is 10 to 1,000 times greater than anything previously flown to collect similar data by NASA

KSC-07pd1238

NASA Image and Video Library

2007-05-17

KENNEDY SPACE CENTER, FLA. -- In the Astrotech Space Operations facility, a computer chip awaits installation on the Dawn spacecraft. The silicon chip holds the names of more than 360,000 space enthusiasts worldwide who signed up to participate in a virtual voyage to the asteroid belt and is about the size of an American five-cent coin. Dawn's mission is to explore two of the asteroid belt's most intriguing and dissimilar occupants: asteroid Vesta and the dwarf planet Ceres. Dawn is scheduled to launch June 30 from Launch Complex 17-B. Photo credit: NASA/Jim Grossmann

KSC-99pp1238

NASA Image and Video Library

1999-10-14

KENNEDY SPACE CENTER, FLA. — Two 34-year-old towers on Launch Complex 41, Cape Canaveral Air Station, lie on the ground amid the black smoke from explosives set to topple them. Weighing two million pounds, the umbilical tower (left) was approximately 200 feet high. The taller 300-foot Mobile Service Tower (right) weighs five million pounds. About 200 pounds of linear-shaped charges were used to topple the towers so that the materials can be recycled. Adjacent to the towers are lightning protection structures, which will remain on the site. The towers are being demolished to make room for Lockheed Martin's 14-acre Vehicle Integration Facility (VIF), under construction. The implosion and removal of the tower debris is expected to be completed in two months. The VIF will be used for Lockheed Martin's Atlas V Launch System.

KSC-03pd1238

NASA Image and Video Library

2003-04-24

KENNEDY SPACE CENTER, FLA. - The mated Pegasus XL and Galaxy Evolution Explorer (GALEX) satellite arrive at Cape Canaveral Air Force Station. The GALEX, to be launched April 28 from an Orbital Sciences L-1011 aircraft, will carry into space an orbiting telescope that will observe a million galaxies across 10 billion years of cosmic history to help astronomers determine when the stars and elements we see today had their origins. The spacecraft will sweep the skies for 28 months using state-of-the-art ultraviolet detectors to single out galaxies dominated by young, hot, short-lived stars that give off a great deal of energy at that wavelength. These galaxies are actively creating stars, and therefore provide a window into the history and causes of star formation in galaxies.

Multiple Neuropeptide-Coding Genes Involved in Planarian Pharynx Extension.

PubMed

Shimoyama, Seira; Inoue, Takeshi; Kashima, Makoto; Agata, Kiyokazu

2016-06-01

Planarian feeding behavior involves three steps: moving toward food, extending the pharynx from their planarian's ventral side after arriving at the food, and ingesting the food through the pharynx. Although pharynx extension is a remarkable behavior, it remains unknown what neuronal cell types are involved in its regulation. To identify neurons involved in regulating pharynx extension, we quantitatively analyzed pharynx extension and sought to identify these neurons by RNA interference (RNAi) and in situ hybridization. This assay, when performed using planarians with amputation of various body parts, clearly showed that the head portion is indispensable for inducing pharynx extension. We thus tested the effects of knockdown of brain neurons such as serotonergic, GABAergic, and dopaminergic neurons by RNAi, but did not observe any effects on pharynx extension behavior. However, animals with RNAi of the Prohormone Convertase 2 (PC2, a neuropeptide processing enzyme) gene did not perform the pharynx extension behavior, suggesting the possible involvement of neuropeptide(s in the regulation of pharynx extension. We screened 24 neuropeptide-coding genes, analyzed their functions by RNAi using the pharynx extension assay system, and identified at least five neuropeptide genes involved in pharynx extension. These was expressed in different cells or neurons, and some of them were expressed in the brain, suggesting complex regulation of planarian feeding behavior by the nervous system.

VizieR Online Data Catalog: Second Planck Catalogue of Compact Sources (PCCS2) (Planck+, 2016)

NASA Astrophysics Data System (ADS)

Planck Collaboration; Ade, P. A. R.; Aghanim, N.; Argueso, F.; Arnaud, M.; Ashdown, M.; Aumont, J.; Baccigalupi, C.; Banday, A. J.; Barreiro, R. B.; Bartolo, N.; Battaner, E.; Beichman, C.; Benabed, K.; Benoit, A.; Benoit-Levy, A.; Bernard, J.-P.; Bersanelli, M.; Bielewicz, P.; Bock, J. J.; Bohringer, H.; Bonaldi, A.; Bonavera, L.; Bond, J. R.; Borrill, J.; Bouchet, F. R.; Boulanger, F.; Bucher, M.; Burigana, C.; Butler, R. C.; Calabrese, E.; Cardoso, J.-F.; Carvalho, P.; Catalano, A.; Challinor, A.; Chamballu, A.; Chary, R.-R.; Chiang, H. C.; Christensen, P. R.; Clemens, M.; Clements, D. L.; Colombi, S.; Colombo, L. P. L.; Combet, C.; Couchot, F.; Coulais, A.; Crill, B. P.; Curto, A.; Cuttaia, F.; Danese, L.; Davies, R. D.; Davis, R. J.; de Bernardis, P.; De Rosa, A.; de Zotti, G.; Delabrouille, J.; Desert, F.-X.; Dickinson, C.; Diego, J. M.; Dole, H.; Donzelli, S.; Dore, O.; Douspis, M.; Ducout, A.; Dupac, X.; Efstathiou, G.; Elsner, F.; Ensslin, T. A.; Eriksen, H. K.; Falgarone, E.; Fergusson, J.; Finelli, F.; Forni, O.; Frailis, M.; Fraisse, A. A.; Franceschi, E.; Frejse, L. A.; Galeotta, S.; Galli, S.; Ganga, K.; Giard, M.; Giraud-Heraud, Y.; Gjerlow, E.; Gonzalez-Nuevo, J.; Gorski, K. M.; Gratton, S.; Gregorio, A.; Gruppuso, A.; Gudmundsson, J. E.; Hansen, F. K.; Hanson, D.; Harrison, D. L.; Helou, G.; Henrot-Versille, S.; Hernandez-Monteagudo, C.; Herranz, D.; Hildebrandt, S. R.; Hivon, E.; Hobson, M.; Holmes, W. A.; Hornstrup, A.; Hovest, W.; Huffenberger, K. M.; Hurier, G.; Jaffe, A. H.; Jaffe, T. R.; Jones, W. C.; Juvela, M.; Keihanen, E.; Keskitalo, R.; Kisner, T. S.; Kneissl, R.; Knoche, J.; Kunz, M.; Kurki-Suonio, H.; Lagache, G.; Lahteenmaki, A.; Lamarre, J.-M.; Lasenby, A.; Lattanzi, M.; Lawrence, C. R.; Leahy, J. P.; Leonardi, R.; Leon-Tavares, J.; Lesgourgues, J.; Levrier, F.; Liguori, M.; Lilje, P. B.; Linden-Vornle, M.; Lopez-Caniego, M.; Lubin, P. M.; Macias-Perez, J. F.; Maggio, G.; Maino, D.; Mandolesi, N.; Mangilli, A.; Maris, M.; Marshall, D. J.; Martin, P. G.; Martinez-Gonzalez, E.; Masi, S.; Matarrese, S.; McGehee, P.; Meinhold, P. R.; Melchiorri, A.; Mendes, L.; Mennella, A.; Migliaccio, M.; Mitra, S.; Miville-Deschenes, M.-A.; Moneti, A.; Montier, L.; Morgante, G.; Mortlock, D.; Moss, A.; Munshi, D.; Murphy, J. A.; Naselsky, P.; Nati, F.; Natoli, P.; Negrello, M.; Netterfield, C. B.; Norgaard-Nielsen, H. U.; Noviello, F.; Novikov, D.; Novikov, I.; Oxborrow, C. A.; Paci, F.; Pagano, L.; Pajot, F.; Paladini, R.; Paoletti, D.; Partridge, B.; Pasian, F.; Patanchon, G.; Pearson, T. J.; Perdereau, O.; Perotto, L.; Perrotta, F.; Pettorino, V.; Piacentini, F.; Piat, M.; Pierpaoli, E.; Pietrobon, D.; Plaszczynski, S.; Pointecouteau, E.; Polenta, G.; Pratt, G. W.; Prezeau, G.; Prunet, S.; Puget, J.-L.; Rachen, J. P.; Reach, W. T.; Rebolo, R.; Reinecke, M.; Remazeilles, M.; Renault, C.; Renzi, A.; Ristorcelli, I.; Rocha, G.; Rosset, C.; Rossetti, M.; Roudier, G.; Rowan-Robinson, M.; Rubino-Martin, J. A.; Rusholme, B.; Sandri, M.; Sanghera, H. S.; Santos, D.; Savelainen, M.; Savini, G.; Scott, D.; Seiffert, M. D.; Shellard, E. P. S.; Spencer, L. D.; Stolyarov, V.; Sudiwala, R.; Sunyaev, R.; Sutton, D.; Suur-Uski, A.-S.; Sygnet, J.-F.; Tauber, J. A.; Terenzi, L.; Toffolatti, L.; Tomasi, M.; Torni Koski, M.; Tristram, M.; Tucci, M.; Tuovinen, J.; Turler, M.; Umana, G.; Valenziano, L.; Valiviita, J.; van Tent, B.; Vielva, P.; Villa, F.; Wade, L. A.; Walter, B.; Wandelt, B. D.; Wehus, I. K.; Yvon, D.; Zacchei, A.; Zonca, A.

2017-01-01

The Low Frequency Instrument (LFI) DPC produced the 30, 44, and 70GHz maps after the completion of eight full surveys (spanning the period 12 August 2009 to 3 August 2013). In addition, special LFI maps covering the period 1 April 2013 to 30 June 2013 were produced in order to compare the Planck flux-density scales with those of the Very Large Array and the Australia Telescope Compact Array, by performing simultaneous observations of a sample of sources over that period. The High Frequency Instrument (HFI) DPC produced the 100, 143, 217, 353, 545, and 857GHz maps after five full surveys (2009 August 12 to 2012 January 11). (16 data files).

Cooperative Extension as a Framework for Health Extension: The Michigan State University Model.

PubMed

Dwyer, Jeffrey W; Contreras, Dawn; Eschbach, Cheryl L; Tiret, Holly; Newkirk, Cathy; Carter, Erin; Cronk, Linda

2017-10-01

The Affordable Care Act charged the Agency for Healthcare Research and Quality to create the Primary Care Extension Program, but did not fund this effort. The idea to work through health extension agents to support health care delivery systems was based on the nationally known Cooperative Extension System (CES). Instead of creating new infrastructure in health care, the CES is an ideal vehicle for increasing health-related research and primary care delivery. The CES, a long-standing component of the land-grant university system, features a sustained infrastructure for providing education to communities. The Michigan State University (MSU) Model of Health Extension offers another means of developing a National Primary Care Extension Program that is replicable in part because of the presence of the CES throughout the United States. A partnership between the MSU College of Human Medicine and MSU Extension formed in 2014, emphasizing the promotion and support of human health research. The MSU Model of Health Extension includes the following strategies: building partnerships, preparing MSU Extension educators for participation in research, increasing primary care patient referrals and enrollment in health programs, and exploring innovative funding. Since the formation of the MSU Model of Health Extension, researchers and extension professionals have made 200+ connections, and grants have afforded savings in salary costs. The MSU College of Human Medicine and MSU Extension partnership can serve as a model to promote health partnerships nationwide between CES services within land-grant universities and academic health centers or community-based medical schools.

Cooperative Extension as a Framework for Health Extension: The Michigan State University Model

PubMed Central

Dwyer, Jeffrey W.; Contreras, Dawn; Tiret, Holly; Newkirk, Cathy; Carter, Erin; Cronk, Linda

2017-01-01

Problem The Affordable Care Act charged the Agency for Healthcare Research and Quality to create the Primary Care Extension Program, but did not fund this effort. The idea to work through health extension agents to support health care delivery systems was based on the nationally known Cooperative Extension System (CES). Instead of creating new infrastructure in health care, the CES is an ideal vehicle for increasing health-related research and primary care delivery. Approach The CES, a long-standing component of the land-grant university system, features a sustained infrastructure for providing education to communities. The Michigan State University (MSU) Model of Health Extension offers another means of developing a National Primary Care Extension Program that is replicable in part because of the presence of the CES throughout the United States. A partnership between the MSU College of Human Medicine and MSU Extension formed in 2014, emphasizing the promotion and support of human health research. The MSU Model of Health Extension includes the following strategies: building partnerships, preparing MSU Extension educators for participation in research, increasing primary care patient referrals and enrollment in health programs, and exploring innovative funding. Outcomes Since the formation of the MSU Model of Health Extension, researchers and extension professionals have made 200+ connections, and grants have afforded savings in salary costs. Next Steps The MSU College of Human Medicine and MSU Extension partnership can serve as a model to promote health partnerships nationwide between CES services within land-grant universities and academic health centers or community-based medical schools. PMID:28353501

A multicenter study shows PTEN deletion is strongly associated with seminal vesicle involvement and extracapsular extension in localized prostate cancer.

PubMed

Troyer, Dean A; Jamaspishvili, Tamara; Wei, Wei; Feng, Ziding; Good, Jennifer; Hawley, Sarah; Fazli, Ladan; McKenney, Jesse K; Simko, Jeff; Hurtado-Coll, Antonio; Carroll, Peter R; Gleave, Martin; Lance, Raymond; Lin, Daniel W; Nelson, Peter S; Thompson, Ian M; True, Lawrence D; Brooks, James D; Squire, Jeremy A

2015-08-01

Loss of the phosphatase and tensin homolog (PTEN) tumor suppressor gene is a promising marker of aggressive prostate cancer. Active surveillance and watchful waiting are increasingly recommended to patients with small tumors felt to be low risk, highlighting the difficulties of Gleason scoring in this setting. There is an urgent need for predictive biomarkers that can be rapidly deployed to aid in clinical decision-making. Our objectives were to assess the incidence and ability of PTEN alterations to predict aggressive disease in a multicenter study. We used recently developed probes optimized for sensitivity and specificity in a four-color FISH deletion assay to study the Canary Retrospective multicenter Prostate Cancer Tissue Microarray (TMA). This TMA was constructed specifically for biomarker validation from radical prostatectomy specimens, and is accompanied by detailed clinical information with long-term follow-up. In 612 prostate cancers, the overall rate of PTEN deletion was 112 (18.3%). Hemizygous PTEN losses were present in 55/612 (9.0%) of cancers, whereas homozygous PTEN deletion was observed in 57/612 (9.3%) of tumors. Significant associations were found between PTEN status and pathologic stage (P < 0.0001), seminal vesicle invasion (P = 0.0008), extracapsular extension (P < 0.0001), and Gleason score (P = 0.0002). In logistic regression analysis of clinical and pathological variables, PTEN deletion was significantly associated with extracapsular extension, seminal vesicle involvement, and higher Gleason score. In the 406 patients in which clinical information was available, PTEN homozygous (P = 0.009) deletion was associated with worse post-operative recurrence-free survival (number of events = 189), pre-operative prostate specific antigen (PSA) (P < 0.001), and pathologic stage (P = 0.03). PTEN status assessed by FISH is an independent predictor for recurrence-free survival in multivariate models, as were seminal

A multicenter study shows PTEN deletion is strongly associated with seminal vesicle involvement and extracapsular extension in localized prostate cancer

PubMed Central

Troyer, Dean A; Jamaspishvili, Tamara; Wei, Wei; Feng, Ziding; Good, Jennifer; Hawley, Sarah; Fazli, Ladan; McKenney, Jesse K; Simko, Jeff; Hurtado-Coll, Antonio; Carroll, Peter R; Gleave, Martin; Lance, Raymond; Lin, Daniel W; Nelson, Peter S; Thompson, Ian M; True, Lawrence D; Brooks, James D; Squire, Jeremy A

2015-01-01

BACKGROUND Loss of the phosphatase and tensin homolog (PTEN) tumor suppressor gene is a promising marker of aggressive prostate cancer. Active surveillance and watchful waiting are increasingly recommended to patients with small tumors felt to be low risk, highlighting the difficulties of Gleason scoring in this setting. There is an urgent need for predictive biomarkers that can be rapidly deployed to aid in clinical decision-making. Our objectives were to assess the incidence and ability of PTEN alterations to predict aggressive disease in a multicenter study. METHODS We used recently developed probes optimized for sensitivity and specificity in a four-color FISH deletion assay to study the Canary Retrospective multicenter Prostate Cancer Tissue Microarray (TMA). This TMA was constructed specifically for biomarker validation from radical prostatectomy specimens, and is accompanied by detailed clinical information with long-term follow-up. RESULTS In 612 prostate cancers, the overall rate of PTEN deletion was 112 (18.3%). Hemizygous PTEN losses were present in 55/612 (9.0%) of cancers, whereas homozygous PTEN deletion was observed in 57/612 (9.3%) of tumors. Significant associations were found between PTEN status and pathologic stage (P < 0.0001), seminal vesicle invasion (P = 0.0008), extracapsular extension (P < 0.0001), and Gleason score (P = 0.0002). In logistic regression analysis of clinical and pathological variables, PTEN deletion was significantly associated with extracapsular extension, seminal vesicle involvement, and higher Gleason score. In the 406 patients in which clinical information was available, PTEN homozygous (P = 0.009) deletion was associated with worse post-operative recurrence-free survival (number of events = 189), pre-operative prostate specific antigen (PSA) (P < 0.001), and pathologic stage (P = 0.03). CONCLUSION PTEN status assessed by FISH is an independent predictor for recurrence-free survival in

77 FR 60948 - Stress Testing of Regulated Entities

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-05

... the stress test. F. Post-Assessment Actions by Regulated Entities--Proposed Sec. 1238.6 Section 1238.6... during each quarter of the stress test planning horizon, for each scenario: (1) Potential losses, pre... regulated by a primary federal financial regulatory agency, to conduct annual stress tests to determine...

Agricultural Extension: Farm Extension Services in Australia, Britain and the United States.

ERIC Educational Resources Information Center

Williams, Donald B.

By analyzing the scope and structure of agricultural extension services in Australia, Great Britain, and the United States, this work attempts to set guidelines for measuring progress and guiding extension efforts. Extension training, agricultural policy, and activities of national, international, state, and provincial bodies are examined. The…

[Juvenile nasopharyngeal angiofibroma with orbital extension].

PubMed

Hervás Ontiveros, A; España Gregori, E; Climent Vallano, L; Rivas Rodero, S; Alamar Velázquez, A; Simal Julián, J A

2015-01-01

The case is presented of a 21 year-old male with a history of left proptosis and diplopia of two weeks of onset. The MRI showed an ethmoid-orbital vascular lesion with anterior skull base invasion and orbital extension. Biopsy of the ethmoid confirmed fibrovascular tissue, which supported the diagnosis of angiofibroma. It is a benign neoplasm with local characteristics of malignancy due to its ability to invade adjacent areas. In this case, the debut presented with manifestations of orbital extension. A broad and multidisciplinary approach is needed in order to improve prognosis. Copyright © 2013 Sociedad Española de Oftalmología. Published by Elsevier España, S.L.U. All rights reserved.

Patterning of inflorescences and flowers by the F-Box protein DOUBLE TOP and the LEAFY homolog ABERRANT LEAF AND FLOWER of petunia.

PubMed

Souer, Erik; Rebocho, Alexandra B; Bliek, Mattijs; Kusters, Elske; de Bruin, Robert A M; Koes, Ronald

2008-08-01

Angiosperms display a wide variety of inflorescence architectures differing in the positions where flowers or branches arise. The expression of floral meristem identity (FMI) genes determines when and where flowers are formed. In Arabidopsis thaliana, this is regulated via transcription of LEAFY (LFY), which encodes a transcription factor that promotes FMI. We found that this is regulated in petunia (Petunia hybrida) via transcription of a distinct gene, DOUBLE TOP (DOT), a homolog of UNUSUAL FLORAL ORGANS (UFO) from Arabidopsis. Mutation of DOT or its tomato (Solanum lycopersicum) homolog ANANTHA abolishes FMI. Ubiquitous expression of DOT or UFO in petunia causes very early flowering and transforms the inflorescence into a solitary flower and leaves into petals. Ectopic expression of DOT or UFO together with LFY or its homolog ABERRANT LEAF AND FLOWER (ALF) in petunia seedlings activates genes required for identity or outgrowth of organ primordia. DOT interacts physically with ALF, suggesting that it activates ALF by a posttranslational mechanism. Our findings suggest a wider role than previously thought for DOT and UFO in the patterning of flowers and indicate that the different roles of LFY and UFO homologs in the spatiotemporal control of floral identity in distinct species result from their divergent expression patterns.

12. VIEW NORTH, ACROSS DECK CENTER AREA SHOWING ASPHALT AND ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

12. VIEW NORTH, ACROSS DECK CENTER AREA SHOWING ASPHALT AND NORTH SIDE GUARD WALL - Route 1 Extension, South Street Viaduct, Spanning Conrail & Wheeler Point Road at South Street, Newark, Essex County, NJ

Extension Approach for an Effective Fisheries and Aquaculture Extension Service in India

ERIC Educational Resources Information Center

Kumaran, M.; Vimala, D. Deboral; Chandrasekaran, V. S.; Alagappan, M.; Raja, S.

2012-01-01

Purpose: Public-funded fisheries extension services have been blamed as poor and responsible for the slow pace of aquaculture development in India. The present investigation aimed to find concrete interventions to streamline the extension service by understanding the research-extension-farmer linkage indirectly in terms of information sources of…

34. PLAN, PROPOSED EXTENSION OF COAL HOUSE, EXTENSIONS OF ENGINE ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

34. PLAN, PROPOSED EXTENSION OF COAL HOUSE, EXTENSIONS OF ENGINE AND COAL HOUSES, DEER ISLAND PUMPING STATION, METROPOLITAN WATER AND SEWERAGE BOARD, METROPOLITAN SEWARAGE WORKS, JANUARY 1909, SHEET NO. 11. Aperture card 6498-11. - Deer Island Pumping Station, Boston, Suffolk County, MA

Design of a composite wing extension for a general aviation aircraft

NASA Technical Reports Server (NTRS)

Adney, P. S.; Horn, W. J.

1984-01-01

A composite wing extension was designed for a typical general aviation aircraft to improve lift curve slope, dihedral effect, and lift to drag ratio. Advanced composite materials were used in the design to evaluate their use as primary structural components in general aviation aircraft. Extensive wind tunnel tests were used to evaluate six extension shapes. The extension shape chosen as the best choice was 28 inches long with a total area of 17 square feet. Subsequent flight tests showed the wing extension's predicted aerodynamic improvements to be correct. The structural design of the wing extension consisted of a hybrid laminate carbon core with outer layers of Kevlar - layed up over a foam interior which acted as an internal support. The laminate skin of the wing extension was designed from strength requirements, and the foam core was included to prevent buckling. A joint lap was recommended to attach the wing extension to the main wing structure.

3. INTERIOR OF SOUTHEAST CORNER OF OPEN CONCOURSE, SHOWING WOODFRAMED ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. INTERIOR OF SOUTHEAST CORNER OF OPEN CONCOURSE, SHOWING WOOD-FRAMED WINDOWS AND CEMENTED TILE AND STEEL CEILING - Pennsylvania Railroad Station, Open Concourse & Concourse Roof Extension, 1101 Liberty Avenue, Pittsburgh, Allegheny County, PA

EXTENSION EDUCATION SYMPOSIUM: reinventing extension as a resource--what does the future hold?

PubMed

Mirando, M A; Bewley, J M; Blue, J; Amaral-Phillips, D M; Corriher, V A; Whittet, K M; Arthur, N; Patterson, D J

2012-10-01

The mission of the Cooperative Extension Service, as a component of the land-grant university system, is to disseminate new knowledge and to foster its application and use. Opportunities and challenges facing animal agriculture in the United States have changed dramatically over the past few decades and require the use of new approaches and emerging technologies that are available to extension professionals. Increased federal competitive grant funding for extension, the creation of eXtension, the development of smartphone and related electronic technologies, and the rapidly increasing popularity of social media created new opportunities for extension educators to disseminate knowledge to a variety of audiences and engage these audiences in electronic discussions. Competitive grant funding opportunities for extension efforts to advance animal agriculture became available from the USDA National Institute of Food and Agriculture (NIFA) and have increased dramatically in recent years. The majority of NIFA funding opportunities require extension efforts to be integrated with research, and NIFA encourages the use of eXtension and other cutting-edge approaches to extend research to traditional clientele and nontraditional audiences. A case study is presented to illustrate how research and extension were integrated to improve the adoption of AI by beef producers. Those in agriculture are increasingly resorting to the use of social media venues such as Facebook, YouTube, LinkedIn, and Twitter to access information required to support their enterprises. Use of these various approaches by extension educators requires appreciation of the technology and an understanding of how the target audiences access information available on social media. Technology to deliver information is changing rapidly, and Cooperative Extension Service professionals will need to continuously evaluate digital technology and social media tools to appropriately integrate them into learning and

35. WEST END ELEVATION, PROPOSED EXTENSION OF COAL HOUSE, EXTENSIONS ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

35. WEST END ELEVATION, PROPOSED EXTENSION OF COAL HOUSE, EXTENSIONS OF ENGINE AND COAL HOUSES, DEER ISLAND PUMPING STATION, METROPOLITAN WATER AND SEWERAGE BOARD, METROPOLITAN SEWERAGE WORKS, JANUARY 1908, SHEET NO. 7. Aperture card 6498-7. - Deer Island Pumping Station, Boston, Suffolk County, MA

After Nerve Injury, Lineage Tracing Shows That Myelin and Remak Schwann Cells Elongate Extensively and Branch to Form Repair Schwann Cells, Which Shorten Radically on Remyelination

PubMed Central

van der Lans, Milou; Benito, Cristina; Wagstaff, Laura J.

2017-01-01

There is consensus that, distal to peripheral nerve injury, myelin and Remak cells reorganize to form cellular columns, Bungner's bands, which are indispensable for regeneration. However, knowledge of the structure of these regeneration tracks has not advanced for decades and the structure of the cells that form them, denervated or repair Schwann cells, remains obscure. Furthermore, the origin of these cells from myelin and Remak cells and their ability to give rise to myelin cells after regeneration has not been demonstrated directly, although these conversions are believed to be central to nerve repair. Using genetic lineage-tracing and scanning-block face electron microscopy, we show that injury of sciatic nerves from mice of either sex triggers extensive and unexpected Schwann cell elongation and branching to form long, parallel processes. Repair cells are 2- to 3-fold longer than myelin and Remak cells and 7- to 10-fold longer than immature Schwann cells. Remarkably, when repair cells transit back to myelinating cells, they shorten ∼7-fold to generate the typically short internodes of regenerated nerves. The present experiments define novel morphological transitions in injured nerves and show that repair Schwann cells have a cell-type-specific structure that differentiates them from other cells in the Schwann cell lineage. They also provide the first direct evidence using genetic lineage tracing for two basic assumptions in Schwann cell biology: that myelin and Remak cells generate the elongated cells that build Bungner bands in injured nerves and that such cells can transform to myelin cells after regeneration. SIGNIFICANCE STATEMENT After injury to peripheral nerves, the myelin and Remak Schwann cells distal to the injury site reorganize and modify their properties to form cells that support the survival of injured neurons, promote axon growth, remove myelin-associated growth inhibitors, and guide regenerating axons to their targets. We show that the

After Nerve Injury, Lineage Tracing Shows That Myelin and Remak Schwann Cells Elongate Extensively and Branch to Form Repair Schwann Cells, Which Shorten Radically on Remyelination.

PubMed

Gomez-Sanchez, Jose A; Pilch, Kjara S; van der Lans, Milou; Fazal, Shaline V; Benito, Cristina; Wagstaff, Laura J; Mirsky, Rhona; Jessen, Kristjan R

2017-09-13

There is consensus that, distal to peripheral nerve injury, myelin and Remak cells reorganize to form cellular columns, Bungner's bands, which are indispensable for regeneration. However, knowledge of the structure of these regeneration tracks has not advanced for decades and the structure of the cells that form them, denervated or repair Schwann cells, remains obscure. Furthermore, the origin of these cells from myelin and Remak cells and their ability to give rise to myelin cells after regeneration has not been demonstrated directly, although these conversions are believed to be central to nerve repair. Using genetic lineage-tracing and scanning-block face electron microscopy, we show that injury of sciatic nerves from mice of either sex triggers extensive and unexpected Schwann cell elongation and branching to form long, parallel processes. Repair cells are 2- to 3-fold longer than myelin and Remak cells and 7- to 10-fold longer than immature Schwann cells. Remarkably, when repair cells transit back to myelinating cells, they shorten ∼7-fold to generate the typically short internodes of regenerated nerves. The present experiments define novel morphological transitions in injured nerves and show that repair Schwann cells have a cell-type-specific structure that differentiates them from other cells in the Schwann cell lineage. They also provide the first direct evidence using genetic lineage tracing for two basic assumptions in Schwann cell biology: that myelin and Remak cells generate the elongated cells that build Bungner bands in injured nerves and that such cells can transform to myelin cells after regeneration. SIGNIFICANCE STATEMENT After injury to peripheral nerves, the myelin and Remak Schwann cells distal to the injury site reorganize and modify their properties to form cells that support the survival of injured neurons, promote axon growth, remove myelin-associated growth inhibitors, and guide regenerating axons to their targets. We show that the

Logo Effects on Brand Extension Evaluations from the Electrophysiological Perspective.

PubMed

Shang, Qian; Pei, Guanxiong; Dai, Shenyi; Wang, Xiaoyi

2017-01-01

Brand extension typically has two strategies: brand name extension (BN) and brand logo extension (BL). The current study explored which strategy (BN or BL) better enhanced the success of dissimilar brand extension and product promotion in enterprises. Event-related potentials (ERPs) were used to investigate electrophysiological processes when subjects evaluated their acceptance of the brand extension using a combined picture of S1 and S2. S1 was a famous brand presented by two identity signs (brand name and brand logo). S2 was a picture of an extension product that belonged to a dissimilar product category than S1. The behavior data showed that BL was more acceptable than BN in the dissimilar brand extension. The neurophysiology process was reflected by a less negative N2 component and a larger P300 component in the BL than in the BN. We suggested that N2 reflected a whole conflict between the brand-product combination and the long-term memory and that P300 could be regarded as the reflection of the categorization process in the working memory.

Logo Effects on Brand Extension Evaluations from the Electrophysiological Perspective

PubMed Central

Shang, Qian; Pei, Guanxiong; Dai, Shenyi; Wang, Xiaoyi

2017-01-01

Brand extension typically has two strategies: brand name extension (BN) and brand logo extension (BL). The current study explored which strategy (BN or BL) better enhanced the success of dissimilar brand extension and product promotion in enterprises. Event-related potentials (ERPs) were used to investigate electrophysiological processes when subjects evaluated their acceptance of the brand extension using a combined picture of S1 and S2. S1 was a famous brand presented by two identity signs (brand name and brand logo). S2 was a picture of an extension product that belonged to a dissimilar product category than S1. The behavior data showed that BL was more acceptable than BN in the dissimilar brand extension. The neurophysiology process was reflected by a less negative N2 component and a larger P300 component in the BL than in the BN. We suggested that N2 reflected a whole conflict between the brand-product combination and the long-term memory and that P300 could be regarded as the reflection of the categorization process in the working memory. PMID:28337121

18. DETAIL OF BACK (EAST SIDE) OF TECHWOOD DORMITORY, SHOWING ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

18. DETAIL OF BACK (EAST SIDE) OF TECHWOOD DORMITORY, SHOWING BACK EXIT AND BRICK CHIMNEY. GRAFFITI IS EXTENSIVE ALONG THIS FACADE. - Techwood Homes, McDaniel Dormitory, 581-587 Techwood Drive, Atlanta, Fulton County, GA

Analyzing the Natural Resource Extension Needs of Spanish-Speakers: A Perspective from Florida

ERIC Educational Resources Information Center

Wyman, Miriam; Escobedo, Francisco; Varela, Sebastian; Asuaje, Cesar; Mayer, Henry; Swisher, Mickie; Hermansen-Baez, Annie

2011-01-01

Hispanics are the country's fastest growing minority group. The study reported here surveyed and assessed Extension agents from two demographically different regions in Florida on perceptions and attitudes about the need, quality, and dissemination of Spanish Extension materials. Results showed Extension programs are important sources of…

REAR OBLIQUE VIEW, SHOWING REAR YARD WITH ORIGINAL CLOTHESLINE ON ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

REAR OBLIQUE VIEW, SHOWING REAR YARD WITH ORIGINAL CLOTHESLINE ON RIGHT SIDE. FOREGROUND SHOWS THE EXTENSIVE GRASSY AREA THAT SURROUNDS THE HOUSE. VIEW FACING WEST - Camp H.M. Smith and Navy Public Works Center Manana Title VII (Capehart) Housing, Four-Bedroom, Single-Family Type 10, Birch Circle, Elm Drive, Elm Circle, and Date Drive, Pearl City, Honolulu County, HI

Interior of Tunnel No. 1356, Stick Pile Tunnel showing timber ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Interior of Tunnel No. 1356, Stick Pile Tunnel showing timber framing and missing posts, looking northeast. - Western Maryland Railway, Cumberland Extension, Pearre to North Branch, from WM milepost 125 to 160, Pearre, Washington County, MD

Analyzing the natural resource extension needs of Spanish-speakers: A perspective from Florida

Treesearch

Miriam Wyman; Francisco Escobedo; Sebastian Varela; Cesar Asuaje; Henry Mayer; Mickie Swisher; Annie Hermansen

2011-01-01

Hispanics are the country's fastest growing minority group. The study reported here surveyed and assessed Extension agents from two demographically different regions in Florida on perceptions and attitudes about the need, quality, and dissemination of Spanish Extension materials. Results showed Extension programs are important sources of information for Spanish-...

Information Search Behaviors of Indian Farmers: Implications for Extension Services

ERIC Educational Resources Information Center

Glendenning, Claire J.; Babu, Suresh C.; Asenso-Okyere, Kwadwo

2012-01-01

Purpose: In India, a national survey conducted in 2003 showed that only 40% of farmers accessed extension. But little is known of the characteristics of farmers who did not access extension. However, this understanding is needed in order to target approaches to farmers, who differ in their access and use of information, that is their information…

Role of the C-terminal extensions of alpha-crystallins. Swapping the C-terminal extension of alpha-crystallin to alphaB-crystallin results in enhanced chaperone activity.

PubMed

Pasta, Saloni Yatin; Raman, Bakthisaran; Ramakrishna, Tangirala; Rao, Ch Mohan

2002-11-29

Several small heat shock proteins contain a well conserved alpha-crystallin domain, flanked by an N-terminal domain and a C-terminal extension, both of which vary in length and sequence. The structural and functional role of the C-terminal extension of small heat shock proteins, particularly of alphaA- and alphaB-crystallins, is not well understood. We have swapped the C-terminal extensions between alphaA- and alphaB-crystallins and generated two novel chimeric proteins, alphaABc and alphaBAc. We have investigated the domain-swapped chimeras for structural and functional alterations. We have used thermal and non-thermal models of protein aggregation and found that the chimeric alphaB with the C-terminal extension of alphaA-crystallin, alphaBAc, exhibits dramatically enhanced chaperone-like activity. Interestingly, however, the chimeric alphaA with the C-terminal extension of alphaB-crystallin, alphaABc, has almost lost its activity. Pyrene solubilization and bis-1-anilino-8-naphthalenesulfonate binding studies show that alphaBAc exhibits more solvent-exposed hydrophobic pockets than alphaA, alphaB, or alphaABc. Significant tertiary structural changes are revealed by tryptophan fluorescence and near-UV CD studies upon swapping the C-terminal extensions. The far-UV CD spectrum of alphaBAc differs from that of alphaB-crystallin whereas that of alphaABc overlaps with that of alphaA-crystallin. Gel filtration chromatography shows alteration in the size of the proteins upon swapping the C-terminal extensions. Our study demonstrates that the unstructured C-terminal extensions play a crucial role in the structure and chaperone activity, in addition to generally believed electrostatic "solubilizer" function.

9. DETAIL OF UNITEDTOD TWINTANDEM STEAM ENGINE, SHOWING HIGHPRESSURE CYLINDER ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

9. DETAIL OF UNITED-TOD TWIN-TANDEM STEAM ENGINE, SHOWING HIGH-PRESSURE CYLINDER AND EXTENSION OF HOUSING. - Republic Iron & Steel Company, Youngstown Works, Blooming Mill & Blooming Mill Engines, North of Poland Avenue, Youngstown, Mahoning County, OH

Subverting the Hegemony of Risk: Vulnerability and Transformation among Australian Show Children

ERIC Educational Resources Information Center

Danaher, P. A.; Danaher, Geoff; Moriarty, Beverley

2007-01-01

Background: Australian show people traverse extensive coastal and inland circuits in eastern and northern Australia, bringing the delights of "sideshow alley" to annual agricultural shows. The show people's mobility for most of the school year makes it difficult for their school-age children to attend "regular" schools…

On Non-Abelian Extensions of 3-Lie Algebras

NASA Astrophysics Data System (ADS)

Song, Li-Na; Makhlouf, Abdenacer; Tang, Rong

2018-04-01

In this paper, we study non-abelian extensions of 3-Lie algebras through Maurer-Cartan elements. We show that there is a one-to-one correspondence between isomorphism classes of non-abelian extensions of 3-Lie algebras and equivalence classes of Maurer-Cartan elements in a DGLA. The structure of the Leibniz algebra on the space of fundamental objects is also analyzed. Supported by National Natural Science Foundation of China under Grant No. 11471139 and National Natural Science Foundation of Jilin Province under Grant No. 20170101050JC

Workplace Issues in Extension--A Delphi Study of Extension Educators

ERIC Educational Resources Information Center

Kroth, Michael; Peutz, Joey

2011-01-01

Using the Delphi technique, expert Extension educators identified and prioritized those workplace issues they believe will be the most important to attract, motivate, and retain Extension educators/agents over the next 5 to 7 years. Obtaining and then utilizing a talented, highly motivated workforce during a period when many will be retiring will…

A New Extension Model: The Memorial Middle School Agricultural Extension and Education Center

ERIC Educational Resources Information Center

Skelton, Peter; Seevers, Brenda

2010-01-01

The Memorial Middle School Agricultural Extension and Education Center is a new model for Extension. The center applies the Cooperative Extension Service System philosophy and mission to developing public education-based programs. Programming primarily serves middle school students and teachers through agricultural and natural resource science…

An Easy Way to Show Memory Color Effects.

PubMed

Witzel, Christoph

2016-01-01

This study proposes and evaluates a simple stimulus display that allows one to measure memory color effects (the effect of object knowledge and memory on color perception). The proposed approach is fast and easy and does not require running an extensive experiment. It shows that memory color effects are robust to minor variations due to a lack of color calibration.

Welding torch gas cup extension

NASA Technical Reports Server (NTRS)

Gordon, Stephen S. (Inventor)

1988-01-01

The invention relates to a gas shielded electric arc welding torch having a detachable gas cup extension which may be of any desired configuration or length. The gas cup extension assembly is mounted on a standard electric welding torch gas cup to enable welding in areas with limited access. The gas cup assembly has an upper tubular insert that fits within the gas cup such that its lower portion protrudes thereform and has a lower tubular extension that is screwed into the lower portion. The extension has a rim to define the outer perimeter of the seat edge about its entrance opening so a gasket may be placed to effect an airtight seal between the gas cup and extension. The tubular extension may be made of metal or cermaic material that can be machined. The novelty lies in the use of an extension assembly for a standard gas cup of an electric arc welding torch which extension assembly is detachable permitting the use of a number of extensions which may be of different configurations and materials and yet fit the standard gas cup.

Generalized probabilistic theories and conic extensions of polytopes

NASA Astrophysics Data System (ADS)

Fiorini, Samuel; Massar, Serge; Patra, Manas K.; Tiwary, Hans Raj

2015-01-01

Generalized probabilistic theories (GPT) provide a general framework that includes classical and quantum theories. It is described by a cone C and its dual C*. We show that whether some one-way communication complexity problems can be solved within a GPT is equivalent to the recently introduced cone factorization of the corresponding communication matrix M. We also prove an analogue of Holevo's theorem: when the cone C is contained in {{{R}}n}, the classical capacity of the channel realized by sending GPT states and measuring them is bounded by log n. Polytopes and optimising functions over polytopes arise in many areas of discrete mathematics. A conic extension of a polytope is the intersection of a cone C with an affine subspace whose projection onto the original space yields the desired polytope. Extensions of polytopes can sometimes be much simpler geometric objects than the polytope itself. The existence of a conic extension of a polytope is equivalent to that of a cone factorization of the slack matrix of the polytope, on the same cone. We show that all 0/1 polytopes whose vertices can be recognized by a polynomial size circuit, which includes as a special case the travelling salesman polytope and many other polytopes from combinatorial optimization, have small conic extension complexity when the cone is the completely positive cone. Using recent exponential lower bounds on the linear extension complexity of polytopes, this provides an exponential gap between the communication complexity of GPT based on the completely positive cone and classical communication complexity, and a conjectured exponential gap with quantum communication complexity. Our work thus relates the communication complexity of generalizations of quantum theory to questions of mainstream interest in the area of combinatorial optimization.

Burnout among Extension Agents in the Ohio Cooperative Extension Service.

ERIC Educational Resources Information Center

Igodan, O. Chris; Newcomb, L. H.

A study examined the extent and causes of burnout among extension agents in Ohio. From the 241 extension agents working in the 88 counties of Ohio, researchers selected a random sample of 101 agents. Included in the sample were 34 agriculture agents, 33 home economics agents. Included in the sample agents were asked to complete a survey…

An influence of extremal edges on boundary extension.

PubMed

Hale, Ralph G; Brown, James M; McDunn, Benjamin A; Siddiqui, Aisha P

2015-08-01

Studies have shown that people consistently remember seeing more of a studied scene than was physically present (e.g., Intraub & Richardson Journal of Experimental Psychology: Learning, Memory, and Cognition, 15, 179-187, 1989). This scene memory error, known as boundary extension, has been suggested to occur due to an observer's failure to differentiate between the contributing sources of information, including the sensory input, amodal continuation beyond the view boundaries, and contextual associations with the main objects and depicted scene locations (Intraub, 2010). Here, "scenes" made of abstract shapes on random-dot backgrounds, previously shown to elicit boundary extension (McDunn, Siddiqui, & Brown Psychonomic Bulletin & Review, 21, 370-375, 2014), were compared with versions made with extremal edges (Palmer & Ghose Psychological Science, 19, 77-84, 2008) added to their borders, in order to examine how boundary extension is influenced when amodal continuation at the borders' view boundaries is manipulated in this way. Extremal edges were expected to reduce boundary extension as compared to the same scenes without them, because extremal edge boundaries explicitly indicate an image's end (i.e., they do not continue past the view boundary). A large and a small difference (16 % and 40 %) between the close and wide-angle views shown during the experiment were tested to examine the effects of both boundary extension and normalization with and without extremal edges. Images without extremal edges elicited typical boundary extension for the 16 % size change condition, whereas the 40 % condition showed signs of normalization. With extremal edges, a reduced amount of boundary extension occurred for the 16 % condition, and only normalization was found for the 40 % condition. Our findings support and highlight the importance of amodal continuation at the view boundaries as a component of boundary extension.

Priorities for Extension.

ERIC Educational Resources Information Center

Hayward, J. A.

Agricultural extension is one component in an array including research, training, education, marketing, international trade, etc. which develop together to bring about growth, and sustained growth determines the priorities for extension. These priorities depend inevitably on the stage of development of a country or region, and on the current…

Association of alpha-thalassemia, TNF-alpha (-308G>A) and VCAM-1 (c.1238G>C) gene polymorphisms with cerebrovascular disease in a newborn cohort of 411 children with sickle cell anemia.

PubMed

Belisário, André Rolim; Nogueira, Frederico Lisboa; Rodrigues, Rahyssa Sales; Toledo, Nayara Evelin; Cattabriga, Ana Luiza Moreira; Velloso-Rodrigues, Cibele; Duarte, Filipe Otávio Chaves; Silva, Célia Maria; Viana, Marcos Borato

2015-01-01

Cerebrovascular disease (CVD) is a severe complication associated with sickle cell anemia. Abnormal transcranial Doppler (TCD) identifies some children at high risk, but other markers would be helpful. This cohort study was aimed at evaluating the effects of genetic biomarkers on the risk of developing CVD in children from Minas Gerais, Brazil. Clinical and hematological data were retrieved from children's records. Outcomes studied were overt ischemic stroke and CVD (overt ischemic stroke, transient ischemic attack, abnormal TCD, or abnormal cerebral angiography). Out of 411 children, 386 (93.9%) had SS genotype, 23 (5.6%) had Sβ(0)-thal and two had severe Sβ(+)-thal (0.5%). Frequency of CVD was lower in Sβ-thal group (p=0.05). No effect of VCAM-1 polymorphism on stroke or CVD risks was detected. Cumulative incidence of stroke was significantly higher for children with TNF-α A allele (p=0.02) and lower for children with HBA deletion (p=0.02). However, no association between CVD and TNF-α -308G>A was found. CVD cumulative incidence was significantly lower for children with HBA deletion (p=0.004). This study found no association between VCAM1 c.1238G>C and stroke. An association between stroke and TNF-α -308A allele has been suggested. Our results have confirmed the protective role of HBA deletion against stroke and CVD. Copyright © 2014 Elsevier Inc. All rights reserved.

On Viviani's Theorem and Its Extensions

ERIC Educational Resources Information Center

Abboud, Elias

2010-01-01

Viviani's theorem states that the sum of distances from any point inside an equilateral triangle to its sides is constant. Here, in an extension of this result, we show, using linear programming, that any convex polygon can be divided into parallel line segments on which the sum of the distances to the sides of the polygon is constant. Let us say…

Signature extension studies

NASA Technical Reports Server (NTRS)

Vincent, R. K.; Thomas, G. S.; Nalepka, R. F.

1974-01-01

The importance of specific spectral regions to signature extension is explored. In the recent past, the signature extension task was focused on the development of new techniques. Tested techniques are now used to investigate this spectral aspect of the large area survey. Sets of channels were sought which, for a given technique, were the least affected by several sources of variation over four data sets and yet provided good object class separation on each individual data set. Using sets of channels determined as part of this study, signature extension was accomplished between data sets collected over a six-day period and over a range of about 400 kilometers.

INTERIOR VIEW SHOWING PROTOTYPE BEGUN APRIL 1988 METHOD OF CUTTING ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

INTERIOR VIEW SHOWING PROTOTYPE BEGUN APRIL 1988 METHOD OF CUTTING GLASS, "PERFECT TIN? MACHINE." MANUFACTURED IN DALLAS, TEXAS AND USED FOR CUTTING GLASS WITH A FINISHED EDGE. - Chambers-McKee Window Glass Company, Cutting House, Clay Avenue Extension, Jeannette, Westmoreland County, PA

Planck 2015 results. IV. Low Frequency Instrument beams and window functions

NASA Astrophysics Data System (ADS)

Planck Collaboration; Ade, P. A. R.; Aghanim, N.; Ashdown, M.; Aumont, J.; Baccigalupi, C.; Banday, A. J.; Barreiro, R. B.; Bartolo, N.; Battaner, E.; Benabed, K.; Benoît, A.; Benoit-Lévy, A.; Bernard, J.-P.; Bersanelli, M.; Bielewicz, P.; Bock, J. J.; Bonaldi, A.; Bonavera, L.; Bond, J. R.; Borrill, J.; Bouchet, F. R.; Bucher, M.; Burigana, C.; Butler, R. C.; Calabrese, E.; Cardoso, J.-F.; Catalano, A.; Chamballu, A.; Christensen, P. R.; Colombi, S.; Colombo, L. P. L.; Crill, B. P.; Curto, A.; Cuttaia, F.; Danese, L.; Davies, R. D.; Davis, R. J.; de Bernardis, P.; de Rosa, A.; de Zotti, G.; Delabrouille, J.; Dickinson, C.; Diego, J. M.; Dole, H.; Donzelli, S.; Doré, O.; Douspis, M.; Ducout, A.; Dupac, X.; Efstathiou, G.; Elsner, F.; Enßlin, T. A.; Eriksen, H. K.; Fergusson, J.; Finelli, F.; Forni, O.; Frailis, M.; Franceschi, E.; Frejsel, A.; Galeotta, S.; Galli, S.; Ganga, K.; Giard, M.; Giraud-Héraud, Y.; Gjerløw, E.; González-Nuevo, J.; Górski, K. M.; Gratton, S.; Gregorio, A.; Gruppuso, A.; Hansen, F. K.; Hanson, D.; Harrison, D. L.; Henrot-Versillé, S.; Herranz, D.; Hildebrandt, S. R.; Hivon, E.; Hobson, M.; Holmes, W. A.; Hornstrup, A.; Hovest, W.; Huffenberger, K. M.; Hurier, G.; Jaffe, A. H.; Jaffe, T. R.; Juvela, M.; Keihänen, E.; Keskitalo, R.; Kiiveri, K.; Kisner, T. S.; Knoche, J.; Kunz, M.; Kurki-Suonio, H.; Lähteenmäki, A.; Lamarre, J.-M.; Lasenby, A.; Lattanzi, M.; Lawrence, C. R.; Leahy, J. P.; Leonardi, R.; Lesgourgues, J.; Levrier, F.; Liguori, M.; Lilje, P. B.; Linden-Vørnle, M.; Lindholm, V.; López-Caniego, M.; Lubin, P. M.; Macías-Pérez, J. F.; Maggio, G.; Maino, D.; Mandolesi, N.; Mangilli, A.; Maris, M.; Martin, P. G.; Martínez-González, E.; Masi, S.; Matarrese, S.; Mazzotta, P.; McGehee, P.; Meinhold, P. R.; Melchiorri, A.; Mendes, L.; Mennella, A.; Migliaccio, M.; Mitra, S.; Montier, L.; Morgante, G.; Mortlock, D.; Moss, A.; Munshi, D.; Murphy, J. A.; Naselsky, P.; Nati, F.; Natoli, P.; Netterfield, C. B.; Nørgaard-Nielsen, H. U.; Novikov, D.; Novikov, I.; Paci, F.; Pagano, L.; Paoletti, D.; Partridge, B.; Pasian, F.; Patanchon, G.; Pearson, T. J.; Perdereau, O.; Perotto, L.; Perrotta, F.; Pettorino, V.; Piacentini, F.; Pierpaoli, E.; Pietrobon, D.; Pointecouteau, E.; Polenta, G.; Pratt, G. W.; Prézeau, G.; Prunet, S.; Puget, J.-L.; Rachen, J. P.; Rebolo, R.; Reinecke, M.; Remazeilles, M.; Renzi, A.; Rocha, G.; Rosset, C.; Rossetti, M.; Roudier, G.; Rubiño-Martín, J. A.; Rusholme, B.; Sandri, M.; Santos, D.; Savelainen, M.; Scott, D.; Seiffert, M. D.; Shellard, E. P. S.; Spencer, L. D.; Stolyarov, V.; Sutton, D.; Suur-Uski, A.-S.; Sygnet, J.-F.; Tauber, J. A.; Terenzi, L.; Toffolatti, L.; Tomasi, M.; Tristram, M.; Tucci, M.; Tuovinen, J.; Umana, G.; Valenziano, L.; Valiviita, J.; Van Tent, B.; Vassallo, T.; Vielva, P.; Villa, F.; Wade, L. A.; Wandelt, B. D.; Watson, R.; Wehus, I. K.; Yvon, D.; Zacchei, A.; Zonca, A.

2016-09-01

This paper presents the characterization of the in-flight beams, the beam window functions, and the associated uncertainties for the Planck Low Frequency Instrument (LFI). The structure of the paper is similar to that presented in the 2013 Planck release; the main differences concern the beam normalization and the delivery of the window functions to be used for polarization analysis. The in-flight assessment of the LFI main beams relies on measurements performed during observations of Jupiter. By stacking data from seven Jupiter transits, the main beam profiles are measured down to -25 dB at 30 and 44 GHz, and down to -30 dB at 70 GHz. It has been confirmed that the agreement between the simulated beams and the measured beams is better than 1% at each LFI frequency band (within the 20 dB contour from the peak, the rms values are 0.1% at 30 and 70 GHz; 0.2% at 44 GHz). Simulated polarized beams are used for the computation of the effective beam window functions. The error budget for the window functions is estimated from both main beam and sidelobe contributions, and accounts for the radiometer band shapes. The total uncertainties in the effective beam window functions are 0.7% and 1% at 30 and 44 GHz, respectively (at ℓ ≈ 600); and 0.5% at 70 GHz (at ℓ ≈ 1000).

INTERIOR VIEW SHOWING BATCH SCALES. SERIES OF FIVE SCALES WITH ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

INTERIOR VIEW SHOWING BATCH SCALES. SERIES OF FIVE SCALES WITH SIX DIFFERENT MATERIALS. MIX SIFTED DOWN FROM SILOS ABOVE. INGREDIENTS: SAND, SODA ASH, DOLOMITE LIMESTONE, NEPHELINE SYENITE, SALT CAKE. - Chambers-McKee Window Glass Company, Batch Plant, Clay Avenue Extension, Jeannette, Westmoreland County, PA

Extension through Partnerships: Research and Education Center Teams with County Extension to Deliver Programs

ERIC Educational Resources Information Center

Mullahey, J. Jeffrey

2011-01-01

Budget reductions have severely affected resources available to deliver agriculture and natural resource Extension programs in Florida. University of Florida/Institute of Food and Agricultural Sciences delivers Extension programming through a unique partnership between research and education centers and county Extension. Science-based information…

3. Oblique view of southwest end, Roundhouse Machine Shop Extension, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. Oblique view of southwest end, Roundhouse Machine Shop Extension, Southern Pacific Railroad Carlin Shops, view to north showing the curvature of the end wall that was the common wall with the Roundhouse, and the large metal-clad doors through which steam locomotives were moved into the Machine Shop (135mm lens). - Southern Pacific Railroad, Carlin Shops, Roundhouse Machine Shop Extension, Foot of Sixth Street, Carlin, Elko County, NV

Evaluation in Extension.

ERIC Educational Resources Information Center

Byrn, Darcie; And Others

The authors have written this manual to aid workers in the Cooperative Extension Service of the United States to be better able to understand and apply the principles and methods of evaluation. The manual contains three sections which cover the nature and place of evaluation in extension work, the evaluation process, and the uses of evaluation…

Climate Envelope Modeling and Dispersal Simulations Show Little Risk of Range Extension of the Shipworm, Teredo navalis (L.), in the Baltic Sea

PubMed Central

Appelqvist, Christin; Al-Hamdani, Zyad K.; Jonsson, Per R.; Havenhand, Jon N.

2015-01-01

The shipworm, Teredo navalis, is absent from most of the Baltic Sea. In the last 20 years, increased frequency of T. navalis has been reported along the southern Baltic Sea coasts of Denmark, Germany, and Sweden, indicating possible range-extensions into previously unoccupied areas. We evaluated the effects of historical and projected near-future changes in salinity, temperature, and oxygen on the risk of spread of T. navalis in the Baltic. Specifically, we developed a simple, GIS-based, mechanistic climate envelope model to predict the spatial distribution of favourable conditions for adult reproduction and larval metamorphosis of T. navalis, based on published environmental tolerances to these factors. In addition, we used a high-resolution three-dimensional hydrographic model to simulate the probability of spread of T. navalis larvae within the study area. Climate envelope modeling showed that projected near-future climate change is not likely to change the overall distribution of T. navalis in the region, but will prolong the breeding season and increase the risk of shipworm establishment at the margins of the current range. Dispersal simulations indicated that the majority of larvae were philopatric, but those that spread over a wider area typically spread to areas unfavourable for their survival. Overall, therefore, we found no substantive evidence for climate-change related shifts in the distribution of T. navalis in the Baltic Sea, and no evidence for increased risk of spread in the near-future. PMID:25768305

Broadening Extension's Capacity--Comparing Extension Agents' and Environmental Educators' Perceptions of Needs and Barriers

ERIC Educational Resources Information Center

Smaldone, Dave; Boone, Deborah A.; Selin, Steve; See, Amanda

2011-01-01

Conservation and environmental education share similar goals with Extension and thus holds partnership potential for Extension. The study reported here compared the needs and barriers faced by environmental educators and Extension agents in West Virginia using a mail survey. Results indicated there were both similarities and differences in the…

Pleiotropy, redundancy and the evolution of flowers.

PubMed

Albert, Victor A; Oppenheimer, David G; Lindqvist, Charlotte

2002-07-01

Most angiosperm flowers are tightly integrated, functionally bisexual shoots that have carpels with enclosed ovules. Flowering plants evolved from within the gymnosperms, which lack this combination of innovations. Paradoxically, phylogenetic reconstructions suggest that the flowering plant lineage substantially pre-dates the evolution of flowers themselves. We provide a model based on known gene regulatory networks whereby positive selection on a single, partially redundant gene duplicate 'trapped' the ancestors of flower-bearing plants into the condensed, bisexual state approximately 130 million years ago. The LEAFY (LFY) gene of Arabidopsis encodes a master regulator that functions as the main conduit of environmental signals to the reproductive developmental program. We directly link the elimination of one LFY paralog, pleiotropically maintained in gymnosperms, to the sudden appearance of flowers in the fossil record.

Computer-Based Methods for Thermodynamic Analysis of Materials Processing.

DTIC Science & Technology

1983-11-30

metallic alloys (12,13), silicides (14),and oxynitride * . systems (15). - . 2. Thermochemical System Employed to Characterize Binary Ill-V Phase Diagrams The...reference to Figure I shows that the stable form of RbF is the sodium chloride S form. Table I shows that OGH -oS -RFRFLS-RFRFLM-12866-.381T J/g.at. (5...KF, BF=(I/3)8aF LF-(I/4)LaF3V PF-(113)PbF 2 S- Sodium Chloride Structures Stable form of NF, KE, RE and (;F L-Liquid, M-Stable form of ZF, KeStable form

Cutoff for extensions of massive gravity and bi-gravity

NASA Astrophysics Data System (ADS)

Matas, Andrew

2016-04-01

Recently there has been interest in extending ghost-free massive gravity, bi-gravity, and multi-gravity by including non-standard kinetic terms and matter couplings. We first review recent proposals for this class of extensions, emphasizing how modifications of the kinetic and potential structure of the graviton and modifications of the coupling to matter are related. We then generalize existing no-go arguments in the metric language to the vielbein language in second-order form. We give an ADM argument to show that the most promising extensions to the kinetic term and matter coupling contain a Boulware-Deser ghost. However, as recently emphasized, we may still be able to view these extensions as effective field theories below some cutoff scale. To address this possibility, we show that there is a decoupling limit where a ghost appears for a wide class of matter couplings and kinetic terms. In particular, we show that there is a decoupling limit where the linear effective vielbein matter coupling contains a ghost. Using the insight we gain from this decoupling limit analysis, we place an upper bound on the cutoff for the linear effective vielbein coupling. This result can be generalized to new kinetic interactions in the vielbein language in second-order form. Combined with recent results, this provides a strong uniqueness argument on the form of ghost-free massive gravity, bi-gravity, and multi-gravity.

Two endogenous proteins that induce cell wall extension in plants

NASA Technical Reports Server (NTRS)

McQueen-Mason, S.; Durachko, D. M.; Cosgrove, D. J.

1992-01-01

Plant cell enlargement is regulated by wall relaxation and yielding, which is thought to be catalyzed by elusive "wall-loosening" enzymes. By employing a reconstitution approach, we found that a crude protein extract from the cell walls of growing cucumber seedlings possessed the ability to induce the extension of isolated cell walls. This activity was restricted to the growing region of the stem and could induce the extension of isolated cell walls from various dicot stems and the leaves of amaryllidaceous monocots, but was less effective on grass coleoptile walls. Endogenous and reconstituted wall extension activities showed similar sensitivities to pH, metal ions, thiol reducing agents, proteases, and boiling in methanol or water. Sequential HPLC fractionation of the active wall extract revealed two proteins with molecular masses of 29 and 30 kD associated with the activity. Each protein, by itself, could induce wall extension without detectable hydrolytic breakdown of the wall. These proteins appear to mediate "acid growth" responses of isolated walls and may catalyze plant cell wall extension by a novel biochemical mechanism.

4. EXTERIOR NORTH SIDE OF BUILDING 102 SHOWING USHAPED SPACE ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. EXTERIOR NORTH SIDE OF BUILDING 102 SHOWING U-SHAPED SPACE BETWEEN KITCHEN NOS. 1 AND 2, SHED-ROOFED EXTENSION TO UTILITY ROOM CONTAINING HOT WATER HEATER, AND ASBESTOS SIDING. VIEW TO SOUTHWEST. - Bishop Creek Hydroelectric System, Plant 6, Cashbaugh-Kilpatrick House, Bishop Creek, Bishop, Inyo County, CA

New Stethoscope With Extensible Diaphragm.

PubMed

Takashina, Tsunekazu; Shimizu, Masashi; Muratake, Torakazu; Mayuzumi, Syuichi

2016-08-25

This study compared the diagnostic efficacy of the common suspended diaphragm stethoscope (SDS) with a new extensible diaphragm stethoscope (EDS) for low-frequency heart sounds. The EDS was developed by using an ethylene propylene diene monomer diaphragm. The results showed that the EDS enhanced both the volume and quality of low-frequency heart sounds, and improved the ability of examiners to auscultate such heart sounds. Based on the results of the sound analysis, the EDS is more efficient than the SDS. (Circ J 2016; 80: 2047-2049).

Control of octopus arm extension by a peripheral motor program.

PubMed

Sumbre, G; Gutfreund, Y; Fiorito, G; Flash, T; Hochner, B

2001-09-07

For goal-directed arm movements, the nervous system generates a sequence of motor commands that bring the arm toward the target. Control of the octopus arm is especially complex because the arm can be moved in any direction, with a virtually infinite number of degrees of freedom. Here we show that arm extensions can be evoked mechanically or electrically in arms whose connection with the brain has been severed. These extensions show kinematic features that are almost identical to normal behavior, suggesting that the basic motor program for voluntary movement is embedded within the neural circuitry of the arm itself. Such peripheral motor programs represent considerable simplification in the motor control of this highly redundant appendage.

EXTENSION IN RURAL COMMUNITIES, A MANUAL FOR AGRICULTURAL AND HOME EXTENSION WORKERS.

ERIC Educational Resources Information Center

SAVILE, A.H.

A PRACTICAL GUIDE IS PROVIDED FOR TRAINERS OF ADVISORY AND EXTENSION WORKERS AND LOCAL LEADERS IN AGRICULTURE AND COMMUNITY DEVELOPMENT IN DEVELOPING NATIONS. BASIC PRINCIPLES OF AGRICULTURAL EXTENSION, COMMUNITY SURVEY PROCEDURES, ELEMENTS OF PROGRAM PLANNING, AND PURPOSES AND METHODS OF PROGRAM EVALUATION ARE DESCRIBED. THEN FOLLOW TWO CHAPTERS…

Robotic hand with modular extensions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Salisbury, Curt Michael; Quigley, Morgan

A robotic device is described herein. The robotic device includes a frame that comprises a plurality of receiving regions that are configured to receive a respective plurality of modular robotic extensions. The modular robotic extensions are removably attachable to the frame at the respective receiving regions by way of respective mechanical fuses. Each mechanical fuse is configured to trip when a respective modular robotic extension experiences a predefined load condition, such that the respective modular robotic extension detaches from the frame when the load condition is met.

Attitudes of Ohio County Extension Agents toward Satellite Video Teleconferencing in Extension Education. A Thesis.

ERIC Educational Resources Information Center

Gerakis, Argyrios

A study was conducted to determine the attitudes of Ohio county extension agents toward satellite video teleconferencing. (Several county extension offices across the state participate in live satellite video teleconferences produced by The Ohio State University. Teleconferences cover a variety of extension education topics, from agriculture to…

Delaminated rotator cuff tear: extension of delamination and cuff integrity after arthroscopic rotator cuff repair.

PubMed

Gwak, Heui-Chul; Kim, Chang-Wan; Kim, Jung-Han; Choo, Hye-Jeung; Sagong, Seung-Yeob; Shin, John

2015-05-01

The purpose of this study was to evaluate the extension of delamination and the cuff integrity after arthroscopic repair of delaminated rotator cuff tears. Sixty-five patients with delaminated rotator cuff tears were retrospectively reviewed. The delaminated tears were divided into full-thickness delaminated tears and partial-thickness delaminated tears. To evaluate the medial extension, we calculated the coronal size of the delaminated portion. To evaluate the posterior extension, we checked the tendon involved. Cuff integrity was evaluated by computed tomography arthrography. The mean medial extension in the full-thickness and partial-thickness delaminated tears was 18.1 ± 6.0 mm and 22.7 ± 6.3 mm, respectively (P = .0084). The posterior extension into the supraspinatus and the infraspinatus was 36.9% and 32.3%, respectively, in the full-thickness delaminated tears, and it was 27.7% and 3.1%, respectively, in the partial-thickness delaminated tears (P = .0043). With regard to cuff integrity, 35 cases of anatomic healing, 10 cases of partial healing defects, and 17 cases of retear were detected. Among the patients with retear and partial healing of the defect, all the partially healed defects showed delamination. Three retear patients showed delamination, and 14 retear patients did not show delamination; the difference was statistically significant (P = .0001). The full-thickness delaminated tears showed less medial extension and more posterior extension than the partial-thickness delaminated tears. Delamination did not develop in retear patients, but delamination was common in the patients with partially healed defects. Copyright © 2015 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Elsevier Inc. All rights reserved.

Extensible Ontological Modeling Framefork for Subject Mediation

NASA Astrophysics Data System (ADS)

Kalinichenko, L. A.; Skvortsov, N. A.

An approach for extensible ontological model construction in a mediation environment intended for heterogeneous information sources integration in various subject domains is presented. A mediator ontological language (MOL) may depend on a subject domain and is to be defined at the mediator consolidation phase. On the other hand, for different information sources different ontological models (languages) can be used to define their own ontologies. Reversible mapping of the source ontological models into MOL is needed for information sources registration at the mediator. An approach for such reversible mapping is demonstrated for a class of the Web information sources. It is assumed that such sources apply the DAML+OIL ontological model. A subset of the hybrid object-oriented and semi-structured canonical mediator data model is used for the core of MOL. Construction of a reversible mapping of DAML+OIL into an extension of the core of MOL is presented in the paper. Such mapping is a necessary pre-requisite for contextualizing and registration of information sources at the mediator. The mapping shows how extensible MOL can be constructed. The approach proposed is oriented on digital libraries where retrieval is focused on information content, rather than on information entities.

Early histological, hormonal, and molecular changes during pineapple (Ananas comosus (L.) Merrill) artificial flowering induction.

PubMed

Espinosa, Maita Eulalia Ávila; Moreira, Rafael Oliveira; Lima, André Almeida; Ságio, Solange Aparecida; Barreto, Horllys Gomes; Luiz, Sara Lazara Pérez; Abreu, Carlos Eduardo Aragón; Yanes-Paz, Ermis; Ruíz, Yanelis Capdesuñer; González-Olmedo, Justo Lorenzo; Chalfun-Júnior, Antonio

2017-02-01

Natural flowering can cause serious scheduling problems in the pineapple (Ananas comosus) industry and increase harvest costs. Pineapple flowering is thought to be triggered by increased ethylene levels and artificial forcing of pineapple flowering is a common practice to promote flowering synchronisation. However, little is known about the early hormonal and molecular changes of pineapple flowering induction and development. Here, we aimed to analyse the molecular, hormonal, and histological changes during artificial pineapple flowering by Ethrel ® 48 treatment. Histological analyses of the shoot apical meristem, leaf gibberellic acid (GA 3 ), and ethylene quantification were carried out during the first 72h after Ethrel ® 48 treatment. Expression profiles from ethylene biosynthesis (AcACS2 and AcACO1), gibberellin metabolism (AcGA2-ox1 and AcDELLA1), and flower development (FT-like gene (AcFT), LFY-like gene (AcLFY), and a PISTILLATA-like gene (AcPI)) genes were analysed during the first 24h after Ethrel ® 48 treatment. Differentiation processes of the shoot apical meristem into flower buds were already present in the first 72h after Ethrel ® 48 treatment. Ethrel ® 48 lead to a reduction in GA 3 levels, probably triggered by elevated ethylene levels and the positive regulation AcGA2-ox1. AcLFY activation upon Ethrel ® 48 may also have contributed to the reduction of GA 3 levels and, along with the up-regulation of AcPI, are probably associated with the flower induction activation. AcFT and AcDELLA1 do not seem to be regulated by GA 3 and ethylene. Decreased GA 3 and increased ethylene levels suggest an accumulation of AcDELLA1, which may display an important role in pineapple flowering induction. Thus, this study shows that molecular, hormonal, and histological changes are present right after Ethrel ® 48 treatment, providing new insights into how pineapple flowering occurs under natural conditions. Copyright © 2016 Elsevier GmbH. All rights reserved.

Extension algorithm for generic low-voltage networks

NASA Astrophysics Data System (ADS)

Marwitz, S.; Olk, C.

2018-02-01

Distributed energy resources (DERs) are increasingly penetrating the energy system which is driven by climate and sustainability goals. These technologies are mostly connected to low- voltage electrical networks and change the demand and supply situation in these networks. This can cause critical network states. Network topologies vary significantly and depend on several conditions including geography, historical development, network design or number of network connections. In the past, only some of these aspects were taken into account when estimating the network investment needs for Germany on the low-voltage level. Typically, fixed network topologies are examined or a Monte Carlo approach is used to quantify the investment needs at this voltage level. Recent research has revealed that DERs differ substantially between rural, suburban and urban regions. The low-voltage network topologies have different design concepts in these regions, so that different network topologies have to be considered when assessing the need for network extensions and investments due to DERs. An extension algorithm is needed to calculate network extensions and investment needs for the different typologies of generic low-voltage networks. We therefore present a new algorithm, which is capable of calculating the extension for generic low-voltage networks of any given topology based on voltage range deviations and thermal overloads. The algorithm requires information about line and cable lengths, their topology and the network state only. We test the algorithm on a radial, a loop, and a heavily meshed network. Here we show that the algorithm functions for electrical networks with these topologies. We found that the algorithm is able to extend different networks efficiently by placing cables between network nodes. The main value of the algorithm is that it does not require any information about routes for additional cables or positions for additional substations when it comes to estimating

21 CFR 123.8 - Verification.

Code of Federal Regulations, 2011 CFR

2011-04-01

... processor shall verify that the HACCP plan is adequate to control food safety hazards that are reasonably... minimum: (1) Reassessment of the HACCP plan. A reassessment of the adequacy of the HACCP plan whenever any changes occur that could affect the hazard analysis or alter the HACCP plan in any way or at least...

21 CFR 123.8 - Verification.

Code of Federal Regulations, 2010 CFR

2010-04-01

... processor shall verify that the HACCP plan is adequate to control food safety hazards that are reasonably... minimum: (1) Reassessment of the HACCP plan. A reassessment of the adequacy of the HACCP plan whenever any changes occur that could affect the hazard analysis or alter the HACCP plan in any way or at least...

21 CFR 123.8 - Verification.

Code of Federal Regulations, 2013 CFR

2013-04-01

... of any consumer complaints that have been received by the processor to determine whether they relate... review of a consumer complaint, reveals the need to take a corrective action. (c) Reassessment of the... use or consumers of the finished product. The reassessment shall be performed by an individual or...

21 CFR 123.8 - Verification.

Code of Federal Regulations, 2014 CFR

2014-04-01

... of any consumer complaints that have been received by the processor to determine whether they relate... review of a consumer complaint, reveals the need to take a corrective action. (c) Reassessment of the... use or consumers of the finished product. The reassessment shall be performed by an individual or...

21 CFR 123.8 - Verification.

Code of Federal Regulations, 2012 CFR

2012-04-01

... of any consumer complaints that have been received by the processor to determine whether they relate... review of a consumer complaint, reveals the need to take a corrective action. (c) Reassessment of the... use or consumers of the finished product. The reassessment shall be performed by an individual or...

Examining eXtension: Diffusion, Disruption, and Adoption among Iowa State University Extension and Outreach Professionals

ERIC Educational Resources Information Center

Taylor, Cayla; Miller, Greg

2016-01-01

As eXtension unveils its new membership model, Iowa State University Extension and Outreach must determine how best to support professionals and clientele using the technology. This article reports on a study that used the diffusion of innovations and disruptive innovation theories to assess Iowa Extension professionals' adoption and perceptions…

Planck 2015 results: IV. Low Frequency Instrument beams and window functions

DOE PAGES

Ade, P. A. R.; Aghanim, N.; Ashdown, M.; ...

2016-09-20

This article presents the characterization of the in-flight beams, the beam window functions, and the associated uncertainties for the Planck Low Frequency Instrument (LFI). The structure of the paper is similar to that presented in the 2013 Planck release; the main differences concern the beam normalization and the delivery of the window functions to be used for polarization analysis. The in-flight assessment of the LFI main beams relies on measurements performed during observations of Jupiter. By stacking data from seven Jupiter transits, the main beam profiles are measured down to -25 dB at 30 and 44 GHz, and down tomore » -30 dB at 70 GHz. It has been confirmed that the agreement between the simulated beams and the measured beams is better than 1% at each LFI frequency band (within the 20 dB contour from the peak, the rms values are 0.1% at 30 and 70 GHz; 0.2% at 44 GHz). Simulated polarized beams are used for the computation of the effective beam window functions. The error budget for the window functions is estimated from both main beam and sidelobe contributions, and accounts for the radiometer band shapes. The total uncertainties in the effective beam window functions are 0.7% and 1% at 30 and 44 GHz, respectively (at ℓ ≈ 600); and 0.5% at 70 GHz (at ℓ ≈ 1000).« less

Dormancy release and flowering time in Ziziphus jujuba Mill., a "direct flowering" fruit tree, has a facultative requirement for chilling.

PubMed

Meir, Michal; Ransbotyn, Vanessa; Raveh, Eran; Barak, Simon; Tel-Zur, Noemi; Zaccai, Michele

2016-03-15

In deciduous fruit trees, the effect of chilling on flowering has mostly been investigated in the "indirect flowering" group, characterized by a period of rest between flower bud formation and blooming. In the present study, we explored the effects of chilling and chilling deprivation on the flowering of Ziziphus jujuba, a temperate deciduous fruit tree belonging to the "direct flowering" group, in which flower bud differentiation, blooming and fruit development occur after dormancy release, during a single growing season. Dormancy release, vegetative growth and flowering time in Z. jujuba cv. Ben-Li were assessed following several treatments of chilling. Chilling treatments quantitatively decreased the timing of vegetative bud dormancy release, thereby accelerating flowering, but had no effect on the time from dormancy release to flowering. Trees grown at a constant temperature of 25°C, without chilling, broke dormancy and flowered, indicating the facultative character of chilling in this species. We measured the expression of Z. jujuba LFY and AP1 homologues (ZjLFY and ZjAP1). Chilling decreased ZjLFY expression in dormant vegetative buds but had no effect on ZjAP1expression, which reached peak expression before dormancy release and at anthesis. In conclusion, chilling is not obligatory for dormancy release of Z. jujuba cv. Ben-Li vegetative buds. However, the exposure to chilling during dormancy does accelerate vegetative bud dormancy release and flowering. Copyright © 2016 Elsevier GmbH. All rights reserved.

INTERIOR VIEW SHOWING FURNACE KEEPER OBSERVING FURNACE THROUGH BLUE GLASS ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

INTERIOR VIEW SHOWING FURNACE KEEPER OBSERVING FURNACE THROUGH BLUE GLASS EVERY TWENTY MINUTES TO DETERMINE SIZE AND TEXTURE OF BATCH AND OTHER VARIABLES. FAN IN FRONT COOLS WORKERS AS THEY CONDUCT REPAIRS. FURNACE TEMPERATURE AT 1572 DEGREES FAHRENHEIT. - Chambers-McKee Window Glass Company, Furnace No. 2, Clay Avenue Extension, Jeannette, Westmoreland County, PA

Low and high frequency instabilities in an explosion-generated-plasma and possibility of wave triplet

NASA Astrophysics Data System (ADS)

Malik, O. P.; Singh, Sukhmander; Malik, Hitendra K.; Kumar, A.

2015-01-01

An explosion-generated-plasma is explored for low and high frequency instabilities by taking into account the drift of all the plasma species together with the dust particles which are charged. The possibility of wave triplet is also discussed based on the solution of dispersion equation and synchronism conditions. High frequency instability (HFI) and low frequency instability (LFI) are found to occur in this system. LFI grows faster with the higher concentration of dust particles, whereas its growth rate goes down if the mass of the dust is higher. The ion and electron temperatures affect its growth in opposite manner and the electron temperature causes this instability to grow. In addition to the instabilities, a simple wave is also observed to propagate, whose velocity is larger for larger wave number, smaller mass of the dust and higher ion temperature.

Separation of crack extension modes in orthotropic delamination models

NASA Technical Reports Server (NTRS)

Beuth, Jack L.

1995-01-01

In the analysis of an interface crack between dissimilar elastic materials, the mode of crack extension is typically not unique, due to oscillatory behavior of near-tip stresses and displacements. This behavior currently limits the applicability of interfacial fracture mechanics as a means to predict composite delamination. The Virtual Crack Closure Technique (VCCT) is a method used to extract mode 1 and mode 2 energy release rates from numerical fracture solutions. The mode of crack extension extracted from an oscillatory solution using the VCCT is not unique due to the dependence of mode on the virtual crack extension length, Delta. In this work, a method is presented for using the VCCT to extract Delta-independent crack extension modes for the case of an interface crack between two in-plane orthotropic materials. The method does not involve altering the analysis to eliminate its oscillatory behavior. Instead, it is argued that physically reasonable, Delta-independent modes of crack extension can be extracted from oscillatory solutions. Knowledge of near-tip fields is used to determine the explicit Delta dependence of energy release rate parameters. Energy release rates are then defined that are separated from the oscillatory dependence on Delta. A modified VCCT using these energy release rate definitions is applied to results from finite element analyses, showing that Delta-independent modes of crack extension result. The modified technique has potential as a consistent method for extracting crack extension modes from numerical solutions. The Delta-independent modes extracted using this technique can also serve as guides for testing the convergence of finite element models. Direct applications of this work include the analysis of planar composite delamination problems, where plies or debonded laminates are modeled as in-plane orthotropic materials.

Conditioned medium of dental pulp cells stimulated by Chinese propolis show neuroprotection and neurite extension in vitro.

PubMed

Kudo, Daichi; Inden, Masatoshi; Sekine, Shin-Ichiro; Tamaoki, Naritaka; Iida, Kazuki; Naito, Eiji; Watanabe, Kazuhiro; Kamishina, Hiroaki; Shibata, Toshiyuki; Hozumi, Isao

2015-03-04

The purpose of this study was to clarify the effect of Chinese propolis on the expression level of neurotrophic factors in dental pulp cells (DPCs). We also investigated that the effects of the conditioned medium (CM) of DPCs stimulated by the propolis against oxidative and endoplasmic reticulum (ER) stresses in human neuroblastoma SH-SY5Y cells, and on neurite extensions in rat adrenal pheochromocytoma PC12 cells. To investigate the effect of the propolis on the levels of neurotrophic factors in DPCs, we performed a qRT-PCR experiment. As results, NGF, but not BDNF and NT-3, in DPCs was significantly elevated by the propolis in a concentration-dependent manner. H2O2-induced cell death was significantly inhibited by the treatment with the CM of DPCs. In addition, the treatment with the propolis-stimulated CM of DPCs had a more protective effect than that with the CM of DPCs. We also examine the effect of the propolis-stimulated CM of DPCs against a tunicamycin-induced ER stress. The treatment with the propolis-stimulated CM as well as the CM of DPCs significantly inhibited tunicamycin-induced cell death. Moreover, the treatment with the propolis-stimulated CM of DPCs significantly induced neurite outgrowth from PC12 cells than that with the CM of DPCs. These results suggest that the CM of DPCs as well as DPCs will be an efficient source of new treatments for neurodegenerative diseases and that the propolis promote the advantage of the CM of DPCs via producing neurotrophic factors. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

The Most Developmentally Truncated Fishes Show Extensive Hox Gene Loss and Miniaturized Genomes

PubMed Central

Malmstrøm, Martin; Britz, Ralf; Matschiner, Michael; Tørresen, Ole K; Hadiaty, Renny Kurnia; Yaakob, Norsham; Tan, Heok Hui; Jakobsen, Kjetill Sigurd; Salzburger, Walter; Rüber, Lukas

2018-01-01

Abstract The world’s smallest fishes belong to the genus Paedocypris. These miniature fishes are endemic to an extreme habitat: the peat swamp forests in Southeast Asia, characterized by highly acidic blackwater. This threatened habitat is home to a large array of fishes, including a number of miniaturized but also developmentally truncated species. Especially the genus Paedocypris is characterized by profound, organism-wide developmental truncation, resulting in sexually mature individuals of <8 mm in length with a larval phenotype. Here, we report on evolutionary simplification in the genomes of two species of the dwarf minnow genus Paedocypris using whole-genome sequencing. The two species feature unprecedented Hox gene loss and genome reduction in association with their massive developmental truncation. We also show how other genes involved in the development of musculature, nervous system, and skeleton have been lost in Paedocypris, mirroring its highly progenetic phenotype. Further, our analyses suggest two mechanisms responsible for the genome streamlining in Paedocypris in relation to other Cypriniformes: severe intron shortening and reduced repeat content. As the first report on the genomic sequence of a vertebrate species with organism-wide developmental truncation, the results of our work enhance our understanding of genome evolution and how genotypes are translated to phenotypes. In addition, as a naturally simplified system closely related to zebrafish, Paedocypris provides novel insights into vertebrate development. PMID:29684203

Characteristics, Views Held of Agricultural Extension Activities, and Communication Behavior of Hsien Extension Supervisors in Taiwan.

ERIC Educational Resources Information Center

Hong, Pi-Feng

Government agencies in Taiwan have carried out agricultural extension programs since 1910, with the assistance of Farmers' Associations. Programs have been expanded since 1953, and now include both general extension (subsidy programs) and educational extension. Comparison of personal characteristics of hsien (county) Farmers' Association…

Steeply-dipping extension fractures in the Newark basin, New Jersey

USGS Publications Warehouse

Herman, G.C.

2009-01-01

Late Triassic and Early Jurassic bedrock in the Newark basin is pervasively fractured as a result of Mesozoic rifting of the east-central North American continental margin. Tectonic rifting imparted systematic sets of steeply-dipping, en ??chelon, Mode I, extension fractures in basin strata including ordinary joints and veins. These fractures are arranged in transitional-tensional arrays resembling normal dip-slip shear zones. They contributed to crustal stretching, sagging, and eventual faulting of basin rift deposits. Extension fractures display progressive linkage and spatial clustering that probably controlled incipient fault growth. They cluster into three prominent strike groups correlated to early, intermediate, and late-stage tectonic events reflecting about 50- 60?? of counterclockwise rotation of incremental stretching directions. Finite strain analyses show that extension fractures allowed the stretching of basin strata by a few percent, and these fractures impart stratigraphic dips up to a few degrees in directions opposing fracture dips. Fracture groups display three-dimensional spatial variability but consistent geometric relations. Younger fractures locally cut across and terminate against older fractures having more complex vein-cement morphologies and bed-normal folds from stratigraphic compaction. A fourth, youngest group of extension fractures occur sporadically and strike about E-W in obliquely inverted crustal blocks. A geometric analysis of overlapping fracture sets shows how fracture groups result from incremental rotation of an extending tectonic plate, and that old fractures can reactivate with oblique slip components in the contemporary, compressive stress regime. ?? 2008 Elsevier Ltd. All rights reserved.

Exploration of the Core and Variable Dimensions of Extensive Reading Research and Pedagogy

ERIC Educational Resources Information Center

Waring, Rob; McLean, Stuart

2015-01-01

The Extensive Reading Foundation's bibliography now boasts over 530 articles with "Extensive Reading" in the title. About 35% of this rich and diverse body of papers were published in the past decade. A meta-review of this literature shows it is quite fragmented as evidenced by considerable variability in the conceptualization of…

Collaboration of Extension and Grape Industry Members to Create a New Extension Publication

ERIC Educational Resources Information Center

Stafne, Eric T.; Ingels, George; Ingels, Jane; Carroll, Becky

2016-01-01

Collaboration is an important part of the interaction between Extension and industry. Successful sharing of workload can provide benefits for both parties. A project to create a workbook to address vineyard sustainability was initiated by members of the Oklahoma grape industry with assistance from land-grant university Extension. Productive…

Evaluation of runner cone extension to dampen pressure pulsations in a Francis model turbine

NASA Astrophysics Data System (ADS)

Gogstad, Peter Joachim; Dahlhaug, Ole Gunnar

2016-11-01

Today's energy market has a high demand of flexibility due to introduction of other intermittent renewables as wind and solar. To ensure a steady power supply, hydro turbines are often forced to operate more at part load conditions. Originally, turbines were built for steady operation around the best efficiency point. The demand of flexibility, combined with old designs has showed an increase in turbines having problems with hydrodynamic instabilities such as pressure pulsations. Different methods have been investigated to mitigate pressure pulsations. Air injection shows a significant reduction of pressure pulsation amplitudes. However, installation of air injection requires extra piping and a compressor. Investigation of other methods such as shaft extension shows promising results for some operational points, but may significantly reduce the efficiency of the turbine at other operational points. The installation of an extension of the runner cone has been investigated at NTNU by Vekve in 2004. This has resulted in a cylindrical extension at Litjfossen Power Plant in Norway, where the bolt suffered mechanical failure. This indicates high amplitude pressure pulsations in the draft tube centre. The high pressure pulsation amplitudes are believed to be related to high tangential velocity in the draft tube. The mentioned runner cone extension has further been developed to a freely rotating extension. The objective is to reduce the tangential velocity in the draft tube and thereby the pressure pulsation amplitudes.

The Brazilian Experience with Agroecological Extension: A Critical Analysis of Reform in a Pluralistic Extension System

ERIC Educational Resources Information Center

Diesel, Vivien; Miná Dias, Marcelo

2016-01-01

Purpose: To analyze the Brazilian experience in designing and implementing a recent extension policy reform based on agroecology, and reflect on its wider theoretical implications for extension reform literature. Design/methodology/approach: Using a critical public analysis we characterize the evolution of Brazilian federal extension policy…

CCM-3/STRIPAK promotes seamless tube extension through endocytic recycling.

PubMed

Lant, Benjamin; Yu, Bin; Goudreault, Marilyn; Holmyard, Doug; Knight, James D R; Xu, Peter; Zhao, Linda; Chin, Kelly; Wallace, Evan; Zhen, Mei; Gingras, Anne-Claude; Derry, W Brent

2015-03-06

The mechanisms governing apical membrane assembly during biological tube development are poorly understood. Here, we show that extension of the C. elegans excretory canal requires cerebral cavernous malformation 3 (CCM-3), independent of the CCM1 orthologue KRI-1. Loss of ccm-3 causes canal truncations and aggregations of canaliculular vesicles, which form ectopic lumen (cysts). We show that CCM-3 localizes to the apical membrane, and in cooperation with GCK-1 and STRIPAK, promotes CDC-42 signalling, Golgi stability and endocytic recycling. We propose that endocytic recycling is mediated through the CDC-42-binding kinase MRCK-1, which interacts physically with CCM-3-STRIPAK. We further show canal membrane integrity to be dependent on the exocyst complex and the actin cytoskeleton. This work reveals novel in vivo roles of CCM-3·STRIPAK in regulating tube extension and membrane integrity through small GTPase signalling and vesicle dynamics, which may help explain the severity of CCM3 mutations in patients.

Translation Invariant Extensions of Finite Volume Measures

NASA Astrophysics Data System (ADS)

Goldstein, S.; Kuna, T.; Lebowitz, J. L.; Speer, E. R.

2017-02-01

We investigate the following questions: Given a measure μ _Λ on configurations on a subset Λ of a lattice L, where a configuration is an element of Ω ^Λ for some fixed set Ω , does there exist a measure μ on configurations on all of L, invariant under some specified symmetry group of L, such that μ _Λ is its marginal on configurations on Λ ? When the answer is yes, what are the properties, e.g., the entropies, of such measures? Our primary focus is the case in which L=Z^d and the symmetries are the translations. For the case in which Λ is an interval in Z we give a simple necessary and sufficient condition, local translation invariance ( LTI), for extendibility. For LTI measures we construct extensions having maximal entropy, which we show are Gibbs measures; this construction extends to the case in which L is the Bethe lattice. On Z we also consider extensions supported on periodic configurations, which are analyzed using de Bruijn graphs and which include the extensions with minimal entropy. When Λ subset Z is not an interval, or when Λ subset Z^d with d>1, the LTI condition is necessary but not sufficient for extendibility. For Z^d with d>1, extendibility is in some sense undecidable.

Hom-associative Ore extensions

NASA Astrophysics Data System (ADS)

Bäck, P.; Richter, J.; Silvestrov, S.

2018-02-01

We introduce hom-associative Ore extensions as non-associative, non-unital Ore extensions with a hom-associative multiplication, as well as give some necessary and sufficient conditions when such exist. Within this framework, we also construct a family of hom-associative Weyl algebras as generalizations of the classical analogue, and prove that they are simple.

[Research progress of larger flexion gap than extension gap in total knee arthroplasty].

PubMed

Zhang, Weisong; Hao, Dingjun

2017-05-01

To summarize the progress of larger flexion gap than extension gap in total knee arthro-plasty (TKA). The domestic and foreign related literature about larger flexion gap than extension gap in TKA, and its impact factors, biomechanical and kinematic features, and clinical results were summarized. During TKA, to adjust the relations of flexion gap and extension gap is one of the key factors of successful operation. The biomechanical, kinematic, and clinical researches show that properly larger flexion gap than extension gap can improve both the postoperative knee range of motion and the satisfaction of patients, but does not affect the stability of the knee joint. However, there are also contrary findings. So adjustment of flexion gap and extension gap during TKA is still in dispute. Larger flexion gap than extension gap in TKA is a new joint space theory, and long-term clinical efficacy, operation skills, and related complications still need further study.

Torsional actuation with extension-torsion composite coupling and a magnetostrictive actuator

NASA Astrophysics Data System (ADS)

Bothwell, Christopher M.; Chandra, Ramesh; Chopra, Inderjit

1995-04-01

An analytical-experimental study of using magnetostrictive actuators in conjunction with an extension-torsion coupled composite tube to actuate a rotor blade trailing-edge flap to actively control helicopter vibration is presented. Thin walled beam analysis based on Vlasov theory was used to predict the induced twist and extension in a composite tube with magnetostrictive actuation. The study achieved good correlation between theory and experiment. The Kevlar-epoxy systems showed good correlation between measured and predicted twist values.

Proximal Interphalangeal Joint Extension Block Splint

PubMed Central

Abboudi, Jack; Jones, Christopher M.

2016-01-01

Background: Extension block splinting of the proximal interphalangeal (PIP) joint is a simple and useful treatment option although the practical application of this technique has remained undefined in the literature. Methods: This article provides a step-by-step technique for the construction of a reliable PIP extension block splint and also reviews basic indications for treatment with a PIP extension block splint as well as other PIP extension block splint designs. Results: The proposed splint design outlined in this article is reliable, easy to reproduce and easy for patients to manage when treated with a PIP extension block splint. Conclusions: PIP extension block splinting has a role for certain injuries and certain post-operative protocols. A reliable splint design that is easy to manage makes this treatment choice more attractive to the surgeon and the patient. PMID:27390555

Planar induction of convergence and extension of the neural plate by the organizer of Xenopus.

PubMed

Keller, R; Shih, J; Sater, A K; Moreno, C

1992-03-01

This paper demonstrates that convergence and extension within the neural plate of Xenopus laevis are regulated by planar inductive interactions with the adjacent Spemann organizer. The companion article (Keller et al.: Developmental Dynamics 193:199-217, 1992) showed that the prospective hindbrain and spinal cord occupy a very short and very wide area just above the Spemann organizer in the early gastrula and that these regions converge and extend greatly during gastrulation and neurulation, using a sequence of radial and mediolateral cell intercalations. In this article, we show that "planar" contact of these regions with the organizer at their vegetal edge until stage 11 is sufficient to induce convergence and extension, after which their convergence and extension become autonomous. Grafts of the organizer in planar contact with uninduced ectodermal tissues induce these ectodermal tissues to converge and extend by a planar inductive signal from the organizer. Labeling of the inducing or responding tissues confirms that only planar interactions occur. Neural convergence and extension are actually hindered in explants deliberately constructed so that vertical interactions occur. These results show unambiguously that the Spemann organizer induces the extraordinary and precocious convergence and extension movements of the Xenopus neural plate by planar interactions acting over short distances.

Nozzle Extension for Safety Air Gun

NASA Technical Reports Server (NTRS)

Zumbrun, H. N.; Croom, Delwin R., Jr.

1986-01-01

New nozzle-extension design overcomes problems and incorporates original commercial nozzle, retaining intrinsic safety features. Components include extension tube, length of which made to suit application; adaptor fitting, and nozzle adaptor repinned to maintain original safety features. Design moves conical airstream to end of extension to blow machine chips away from operator. Nozzle-extension modification allows safe and efficient operation of machine tools while maintaining integrity of orginial safety-air-gun design.

Designing and application of SAN extension interface based on CWDM

NASA Astrophysics Data System (ADS)

Qin, Leihua; Yu, Shengsheng; Zhou, Jingli

2005-11-01

As Fibre Channel (FC) becomes the protocol of choice within corporate data centers, enterprises are increasingly deploying SANs in their data central. In order to mitigate the risk of losing data and improve the availability of data, more and more enterprises are increasingly adopting storage extension technologies to replicate their business critical data to a secondary site. Transmitting this information over distance requires a carrier grade environment with zero data loss, scalable throughput, low jitter, high security and ability to travel long distance. To address this business requirements, there are three basic architectures for storage extension, they are Storage over Internet Protocol, Storage over Synchronous Optical Network/Synchronous Digital Hierarchy (SONET/SDH) and Storage over Dense Wavelength Division Multiplexing (DWDM). Each approach varies in functionality, complexity, cost, scalability, security, availability , predictable behavior (bandwidth, jitter, latency) and multiple carrier limitations. Compared with these connectiviy technologies,Coarse Wavelength Division Multiplexing (CWDM) is a Simplified, Low Cost and High Performance connectivity solutions for enterprises to deploy their storage extension. In this paper, we design a storage extension connectivity over CWDM and test it's electrical characteristic and random read and write performance of disk array through the CWDM connectivity, testing result show us that the performance of the connectivity over CWDM is acceptable. Furthermore, we propose three kinds of network architecture of SAN extension based on CWDM interface. Finally the credit-Based flow control mechanism of FC, and the relationship between credits and extension distance is analyzed.

Bringing the DuPont Profitability Model to Extension

ERIC Educational Resources Information Center

Roucan-Kane, Maud; Wolfskill, L. A.; Boehlje, Michael D.; Gray, Allan W.

2013-01-01

This article discusses a financial training program used by Deere and Company for almost 10 years. The objective is to describe the program and to discuss a pre-test/post-test methodology to test the effectiveness of a program for possible duplication by Extension. Results show that participants significantly improved from the pre-test to the…

Global dynamics for switching systems and their extensions by linear differential equations

NASA Astrophysics Data System (ADS)

Huttinga, Zane; Cummins, Bree; Gedeon, Tomáš; Mischaikow, Konstantin

2018-03-01

Switching systems use piecewise constant nonlinearities to model gene regulatory networks. This choice provides advantages in the analysis of behavior and allows the global description of dynamics in terms of Morse graphs associated to nodes of a parameter graph. The parameter graph captures spatial characteristics of a decomposition of parameter space into domains with identical Morse graphs. However, there are many cellular processes that do not exhibit threshold-like behavior and thus are not well described by a switching system. We consider a class of extensions of switching systems formed by a mixture of switching interactions and chains of variables governed by linear differential equations. We show that the parameter graphs associated to the switching system and any of its extensions are identical. For each parameter graph node, there is an order-preserving map from the Morse graph of the switching system to the Morse graph of any of its extensions. We provide counterexamples that show why possible stronger relationships between the Morse graphs are not valid.

Global dynamics for switching systems and their extensions by linear differential equations.

PubMed

Huttinga, Zane; Cummins, Bree; Gedeon, Tomáš; Mischaikow, Konstantin

2018-03-15

Switching systems use piecewise constant nonlinearities to model gene regulatory networks. This choice provides advantages in the analysis of behavior and allows the global description of dynamics in terms of Morse graphs associated to nodes of a parameter graph. The parameter graph captures spatial characteristics of a decomposition of parameter space into domains with identical Morse graphs. However, there are many cellular processes that do not exhibit threshold-like behavior and thus are not well described by a switching system. We consider a class of extensions of switching systems formed by a mixture of switching interactions and chains of variables governed by linear differential equations. We show that the parameter graphs associated to the switching system and any of its extensions are identical. For each parameter graph node, there is an order-preserving map from the Morse graph of the switching system to the Morse graph of any of its extensions. We provide counterexamples that show why possible stronger relationships between the Morse graphs are not valid.

Maximal analytic extension and hidden symmetries of the dipole black ring

NASA Astrophysics Data System (ADS)

Armas, Jay

2011-12-01

We construct analytic extensions across the Killing horizons of non-extremal and extremal dipole black rings in Einstein-Maxwell’s theory using different methods. We show that these extensions are non-globally hyperbolic, have multiple asymptotically flat regions and, in the non-extremal case, are also maximal and timelike complete. Moreover, we find that in both cases, the causal structure of the maximally extended spacetime resembles that of the four-dimensional Reissner-Nordström black hole. Furthermore, motivated by the physical interpretation of one of these extensions, we find a separable solution to the Hamilton-Jacobi equation corresponding to zero energy null geodesics and relate it to the existence of a conformal Killing tensor and a conformal Killing-Yano tensor in a specific dimensionally reduced spacetime.

EXTENSION EDUCATION SYMPOSIUM: Getting the most out of your extension appointment and still having a life.

PubMed

Powers, W; Cockett, N; Lardy, G

2017-04-01

Managing the demands of an academic appointment in extension can be a challenging task. Demands from constituent groups, expectations of supervisors, and rigors of promotion and tenure processes can create pressures that young faculty did not expect. Throw in spousal and family duties and you have created a situation that many will find hard to navigate. However, there are ways to cope and, even better news, there are ways to excel in meeting the demands of an academic appointment and enjoying life. Because many new extension faculty members do not have prior experience in extension, best practices in documenting programs and extension scholarship over the pretenure period are provided in this paper. Appointments that include both research and extension are quite common at many land grant universities. The advantages of joint appointments are numerous and include the fact that more and more grant agencies are seeking integrated research, teaching, and/or extension projects. However, the time demands of joint appointments can be challenging. Joint appointments can be designed to help faculty members conduct important translational research and have it be applied in a production setting. By seeking commonalities in research and extension efforts, joint appointments can be very synergistic. Development of highly successful programs requires planning on the front end with an emphasis on an in-depth needs assessment to determine stakeholder needs for both research and extension. Impact assessment should be part of this planning effort. Performing as a successful extension faculty member while maintaining relationships outside of work is challenging and requires deliberate effort on the part of employees and supervisors to realize there is more to life than work. Some authors have referred to this as work-life balance, but it may be more helpful to think of it as work-life effectiveness. To do this, one needs to 1) define what success looks like, 2) set boundaries and

Survey of veterinary extension in the United States.

PubMed

Sischo, W M; Floyd, J G; McKean, J D; Hueston, W D

1999-11-15

To assess veterinary extension in the United States as perceived by veterinary extension personnel. Cross-sectional survey. Extension veterinarians in the United States. 2 surveys were designed and mailed to extension veterinarians listed by the USDA and the American Association of Extension Veterinarians. 34 states had > or = 1 extension veterinarian. The majority (> 60%) of extension veterinarians did not commit time to resident education and were not involved in research activities. Paradoxically, 23% of responding extension veterinarians did not report extension work. Programs for food animal producers, horse owners, and companion animal owners were provided by 100, 63, and 37% of states, respectively. Continuing education (CE) programs were provided for food animal veterinarians, equine veterinarians, and companion animal veterinarians by 96, 63, and 52% of states, respectively. Challenges facing veterinary extension included limited recognition of veterinary extension activities by universities, lack of university personnel to support CE programs, and decreased support for companion animal extension programs. Extension veterinarians need to identify and clearly articulate the mission of veterinary extension, develop more collaborative programs across regions, and continue to serve as catalysts to bring diverse constituents together. Extension veterinarians must distinguish their mission not solely as information transfer, which can be accomplished in a variety of ways outside of extension, but as a coherent and consistent program of education and policy developed on a national level and distributed locally.

A comparison of the views of extension agents and farmers regarding extension education courses in Dezful, Iran

NASA Astrophysics Data System (ADS)

Nazarzadeh Zare, Mohsen; Dorrani, Kamal; Gholamali Lavasani, Masoud

2012-11-01

Background and purpose : This study examines the views of farmers and extension agents participating in extension education courses in Dezful, Iran, with regard to problems with these courses. It relies upon a descriptive methodology, using a survey as its instrument. Sample : The statistical population consisted of 5060 farmers and 50 extension agents; all extension agents were studied owing to their small population and a sample of 466 farmers was selected based on the stratified ratio sampling method. For the data analysis, statistical procedures including the t-test and factor analysis were used. Results : The results of factor analysis on the views of farmers indicated that these courses have problems such as inadequate use of instructional materials by extension agents, insufficient employment of knowledgeable and experienced extension agents, bad and inconvenient timing of courses for farmers, lack of logical connection between one curriculum and prior ones, negligence in considering the opinions of farmers in arranging the courses, and lack of information about the time of courses. The findings of factor analysis on the views of extension agents indicated that these courses suffer from problems such as use of consistent methods of instruction for teaching curricula, and lack of continuity between courses and their levels and content. Conclusions : Recommendations include: listening to the views of farmers when planning extension courses; providing audiovisual aids, pamphlets and CDs; arranging courses based on convenient timing for farmers; using incentives to encourage participation; and employing extension agents with knowledge of the latest agricultural issues.

Extensive analysis of native and non-native Centaurea solstitialis L. populations across the world shows no traces of polyploidization

PubMed Central

Montesinos, Daniel; Eren, Özkan; Lortie, Christopher J.; French, Kristine; Cavieres, Lohengrin A.; Sotes, Gastón J.; Hierro, José L.; Jorge, Andreia; Loureiro, João

2017-01-01

Centaurea solstitialis L. (yellow starthistle, Asteraceae) is a Eurasian native plant introduced as an exotic into North and South America, and Australia, where it is regarded as a noxious invasive. Changes in ploidy level have been found to be responsible for numerous plant biological invasions, as they are involved in trait shifts critical to invasive success, like increased growth rate and biomass, longer life-span, or polycarpy. C. solstitialis had been reported to be diploid (2n = 2x = 16 chromosomes), however, actual data are scarce and sometimes contradictory. We determined for the first time the absolute nuclear DNA content by flow cytometry and estimated ploidy level in 52 natural populations of C. solstitialis across its native and non-native ranges, around the world. All the C. solstitialis populations screened were found to be homogeneously diploid (average 2C value of 1.72 pg, SD = ±0.06 pg), with no significant variation in DNA content between invasive and non-invasive genotypes. We did not find any meaningful difference among the extensive number of native and non-native C. solstitialis populations sampled around the globe, indicating that the species invasive success is not due to changes in genome size or ploidy level. PMID:28828232

Extensive analysis of native and non-native Centaurea solstitialis L. populations across the world shows no traces of polyploidization.

PubMed

Irimia, Ramona-Elena; Montesinos, Daniel; Eren, Özkan; Lortie, Christopher J; French, Kristine; Cavieres, Lohengrin A; Sotes, Gastón J; Hierro, José L; Jorge, Andreia; Loureiro, João

2017-01-01

Centaurea solstitialis L. (yellow starthistle, Asteraceae) is a Eurasian native plant introduced as an exotic into North and South America, and Australia, where it is regarded as a noxious invasive. Changes in ploidy level have been found to be responsible for numerous plant biological invasions, as they are involved in trait shifts critical to invasive success, like increased growth rate and biomass, longer life-span, or polycarpy. C . solstitialis had been reported to be diploid (2 n  = 2 x  = 16 chromosomes), however, actual data are scarce and sometimes contradictory. We determined for the first time the absolute nuclear DNA content by flow cytometry and estimated ploidy level in 52 natural populations of C . solstitialis across its native and non-native ranges, around the world. All the C. solstitialis populations screened were found to be homogeneously diploid (average 2C value of 1.72 pg, SD = ±0.06 pg), with no significant variation in DNA content between invasive and non-invasive genotypes. We did not find any meaningful difference among the extensive number of native and non-native C . solstitialis populations sampled around the globe, indicating that the species invasive success is not due to changes in genome size or ploidy level.

Two types of lateral extension in juvenile nasopharyngeal angiofibroma: diagnostic and therapeutic management.

PubMed

Szymańska, Anna; Szymański, Marcin; Czekajska-Chehab, Elżbieta; Szczerbo-Trojanowska, Małgorzata

2015-01-01

Juvenile nasopharyngeal angiofibroma is a benign, locally aggressive nasopharyngeal tumor. Apart from anterior lateral extension to the pterygopalatine fossa, it may spread laterally posterior to the pterygoid process, showing posterior lateral growth pattern, which is less common and more difficult to identify during surgery. We analyzed the routes of lateral spread, modalities useful in its diagnosis, the incidence of lateral extension and its influence on outcomes of surgical treatment. The records of 37 patients with laterally extending JNA treated at our institution between 1987 and 2011 were retrospectively evaluated. Computed tomography was performed in all patients and magnetic resonance imaging in 17 (46 %) patients. CT and MRI were evaluated to determine routes and extension of JNA lateral spread. Anterior lateral extension to the pterygopalatine fossa occurred in 36 (97 %) patients and further to the infratemporal fossa in 20 (54 %) patients. In 16 (43 %) cases posterior lateral spread was observed: posterior to the pterygoid process and/or between its plates. The recurrence rate was 29.7 % (11/37). The majority of residual lesions was located behind the pterygoid process (7/11). Recurrent disease occurred in 3/21 patients with anterior lateral extension, in 7/15 patients with both types of lateral extensions and in 1 patient with posterior lateral extension. JNA posterior lateral extension may spread behind the pterygoid process or between its plates. The recurrence rate in patients with anterior and/or posterior lateral extension is significantly higher than in patients with anterior lateral extension only. Both CT and MRI allow identification of the anterior and posterior lateral extensions.

Building and Managing Makerspaces in Extension

ERIC Educational Resources Information Center

Francis, Dave; Hill, Paul; Graham, Dallini; Swadley, Emy; Esplin, Kaleb

2017-01-01

As traditional face-to-face Extension office interactions are supplanted by online education options, the makerspace offers a venue for authentic engagement between Extension and the community. In makerspaces, learners make and learn from one another in a cooperative learning environment. Through involvement in the maker movement, Extension has an…

75 FR 48921 - Administrative Guidance for Multistate Extension Activities and Integrated Research and Extension...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-12

.... Section 105 of AREERA amended the Smith-Lever Act to require that a specified amount of agricultural... Hatch Act and Smith-Lever Act to require that a specified amount of agricultural research and extension... Smith- Lever Act funds on multistate extension activities and 25 percent on integrated research and...

Improving Disability Awareness among Extension Agents

ERIC Educational Resources Information Center

Mahadevan, Lakshmi; Peterson, Rick L.; Grenwelge, Cheryl

2014-01-01

Increasing prevalence rates and legislative mandates imply that educators, parents, and Extension agents will need better tools and resources to meet the needs of special populations. The Texas A&M AgriLife Extension Service addresses this issue by using e-learning tools. Extension agents can take advantage of these courses to gain critical…

24 CFR 968.235 - Time extensions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Time extensions. 968.235 Section... Fewer Than 250 Units) § 968.235 Time extensions. A PHA shall not obligate or expend funds after the... time extension, as follows: (a) Certification. A PHA may extend an obligation or expenditure deadline...

24 CFR 968.235 - Time extensions.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false Time extensions. 968.235 Section... Fewer Than 250 Units) § 968.235 Time extensions. A PHA shall not obligate or expend funds after the... time extension, as follows: (a) Certification. A PHA may extend an obligation or expenditure deadline...

24 CFR 968.235 - Time extensions.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 4 2012-04-01 2012-04-01 false Time extensions. 968.235 Section... Fewer Than 250 Units) § 968.235 Time extensions. A PHA shall not obligate or expend funds after the... time extension, as follows: (a) Certification. A PHA may extend an obligation or expenditure deadline...

24 CFR 968.235 - Time extensions.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 4 2013-04-01 2013-04-01 false Time extensions. 968.235 Section... Fewer Than 250 Units) § 968.235 Time extensions. A PHA shall not obligate or expend funds after the... time extension, as follows: (a) Certification. A PHA may extend an obligation or expenditure deadline...

Redundancy checking algorithms based on parallel novel extension rule

NASA Astrophysics Data System (ADS)

Liu, Lei; Yang, Yang; Li, Guangli; Wang, Qi; Lü, Shuai

2017-05-01

Redundancy checking (RC) is a key knowledge reduction technology. Extension rule (ER) is a new reasoning method, first presented in 2003 and well received by experts at home and abroad. Novel extension rule (NER) is an improved ER-based reasoning method, presented in 2009. In this paper, we first analyse the characteristics of the extension rule, and then present a simple algorithm for redundancy checking based on extension rule (RCER). In addition, we introduce MIMF, a type of heuristic strategy. Using the aforementioned rule and strategy, we design and implement RCHER algorithm, which relies on MIMF. Next we design and implement an RCNER (redundancy checking based on NER) algorithm based on NER. Parallel computing greatly accelerates the NER algorithm, which has weak dependence among tasks when executed. Considering this, we present PNER (parallel NER) and apply it to redundancy checking and necessity checking. Furthermore, we design and implement the RCPNER (redundancy checking based on PNER) and NCPPNER (necessary clause partition based on PNER) algorithms as well. The experimental results show that MIMF significantly influences the acceleration of algorithm RCER in formulae on a large scale and high redundancy. Comparing PNER with NER and RCPNER with RCNER, the average speedup can reach up to the number of task decompositions when executed. Comparing NCPNER with the RCNER-based algorithm on separating redundant formulae, speedup increases steadily as the scale of the formulae is incrementing. Finally, we describe the challenges that the extension rule will be faced with and suggest possible solutions.

48 CFR 52.211-13 - Time Extensions.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 2 2013-10-01 2013-10-01 false Time Extensions. 52.211-13... Time Extensions. As prescribed in 11.503(c), insert the following clause: Time Extensions (SEP 2000) Time extensions for contract changes will depend upon the extent, if any, by which the changes cause...

48 CFR 52.211-13 - Time Extensions.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 2 2014-10-01 2014-10-01 false Time Extensions. 52.211-13... Time Extensions. As prescribed in 11.503(c), insert the following clause: Time Extensions (SEP 2000) Time extensions for contract changes will depend upon the extent, if any, by which the changes cause...

48 CFR 52.211-13 - Time Extensions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 2 2011-10-01 2011-10-01 false Time Extensions. 52.211-13... Time Extensions. As prescribed in 11.503(c), insert the following clause: Time Extensions (SEP 2000) Time extensions for contract changes will depend upon the extent, if any, by which the changes cause...

48 CFR 52.211-13 - Time Extensions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 2 2012-10-01 2012-10-01 false Time Extensions. 52.211-13... Time Extensions. As prescribed in 11.503(c), insert the following clause: Time Extensions (SEP 2000) Time extensions for contract changes will depend upon the extent, if any, by which the changes cause...

Two solitons oblique collision in anisotropic non-extensive dusty plasma

NASA Astrophysics Data System (ADS)

El-Labany, S. K.; El-Taibany, W. F.; Behery, E. E.; Fouda, S. M.

2017-03-01

Using an extended Poincaré-Lighthill-Kue method, the oblique collision of two dust acoustic solitons (DASs) in a magnetized non-extensive plasma with the effect of dust pressure anisotropy is studied. The dust fluid is supposed to have an arbitrary charge. A couple of Korteweg-de Vries (KdV) equations are derived for the colliding DASs. The phase shift of each soliton is obtained. It is found that the dust pressure anisotropy, the non-extensive parameter for electrons and ions, plays an important role in determining the collision phase shifts. The present results show that, for the negative dust case, the phase shift of the first soliton decreases, while that of the second soliton increases as either the dust pressure ratio increases or the ion non-extensive parameter decreases. On the other hand, for the positive dust case, the phase shift of the first soliton decreases, while the phase shift of the second soliton increases as either the dust pressure ratio or the ion non-extensive parameter increases. The application of the present findings to some dusty plasma phenomena occurring in space and laboratory plasmas is briefly discussed.

Poincare inequalities, uniform domains and extension properties for Newton-Sobolev functions in metric spaces

NASA Astrophysics Data System (ADS)

Bjorn, Jana; Shanmugalingam, Nageswari

2007-08-01

In the setting of metric measure spaces equipped with a doubling measure supporting a weak p-Poincare inequality with 1[less-than-or-equals, slant]p<[infinity], we show that any uniform domain [Omega] is an extension domain for the Newtonian space N1,p([Omega]) and that [Omega], together with the metric and the measure inherited from X, supports a weak p-Poincare inequality. For p>1, we obtain a near characterization of N1,p-extension domains with local estimates for the extension operator.

A Geographically Diverse Collection of Schizosaccharomyces pombe Isolates Shows Limited Phenotypic Variation but Extensive Karyotypic Diversity

PubMed Central

Brown, William R. A.; Liti, Gianni; Rosa, Carlos; James, Steve; Roberts, Ian; Robert, Vincent; Jolly, Neil; Tang, Wen; Baumann, Peter; Green, Carter; Schlegel, Kristina; Young, Jonathan; Hirchaud, Fabienne; Leek, Spencer; Thomas, Geraint; Blomberg, Anders; Warringer, Jonas

2011-01-01

The fission yeast Schizosaccharomyces pombe has been widely used to study eukaryotic cell biology, but almost all of this work has used derivatives of a single strain. We have studied 81 independent natural isolates and 3 designated laboratory strains of Schizosaccharomyces pombe. Schizosaccharomyces pombe varies significantly in size but shows only limited variation in proliferation in different environments compared with Saccharomyces cerevisiae. Nucleotide diversity, π, at a near neutral site, the central core of the centromere of chromosome II is approximately 0.7%. Approximately 20% of the isolates showed karyotypic rearrangements as detected by pulsed field gel electrophoresis and filter hybridization analysis. One translocation, found in 6 different isolates, including the type strain, has a geographically widespread distribution and a unique haplotype and may be a marker of an incipient speciation event. All of the other translocations are unique. Exploitation of this karyotypic diversity may cast new light on both the biology of telomeres and centromeres and on isolating mechanisms in single-celled eukaryotes. PMID:22384373

14 CFR 13.213 - Extension of time.

Code of Federal Regulations, 2010 CFR

2010-01-01

... INVESTIGATIVE AND ENFORCEMENT PROCEDURES Rules of Practice in FAA Civil Penalty Actions § 13.213 Extension of... parties agree to the extension. (b) Written motion. A party shall file a written motion for an extension... good cause for the late filing is shown. A party filing a written motion for an extension of time shall...

Balancing sub- and supra-salt strain in salt-influenced rifts: Implications for extension estimates

NASA Astrophysics Data System (ADS)

Coleman, Alexander J.; Jackson, Christopher A.-L.; Duffy, Oliver B.

2017-09-01

The structural style of salt-influenced rifts may differ from those formed in predominantly brittle crust. Salt can decouple sub- and supra-salt strain, causing sub-salt faults to be geometrically decoupled from, but kinematically coupled to and responsible for, supra-salt forced folding. Salt-influenced rifts thus contain more folds than their brittle counterparts, an observation often ignored in extension estimates. Fundamental to determining whether sub- and supra-salt structures are kinematically coherent, and the relative contributions of thin- (i.e. gravity-driven) and thick-skinned (i.e. whole-plate stretching) deformation to accommodating rift-related strain, is our ability to measure extension at both structural levels. We here use published physical models of salt-influenced extension to show that line-length estimates yield more accurate values of sub- and supra-salt extension compared to fault-heave, before applying these methods to seismic data from the Halten Terrace, offshore Norway. We show that, given the abundance of ductile deformation in salt-influenced rifts, significant amounts of extension may be ignored, leading to the erroneous interpretations of thin-skinned, gravity-gliding. If a system is kinematically coherent, supra-salt structures can help predict the occurrence and kinematics of sub-salt faults that may be poorly imaged and otherwise poorly constrained.

Louisiana Extension Educators' Perceptions of the Benefit and Relevance of Participating in an International Extension Experience toward Their Career

ERIC Educational Resources Information Center

McClure, Carli; Danjean, Shelli; Bunch, J. C.; Machtmes, Krisanna; Kotrlik, Joe W.

2014-01-01

The purpose of this study was to assess Extension educators' perceptions of the benefit and relevance of an international Extension experience (IEE) toward their career. It was concluded that almost two-thirds of Extension educators perceive that participation in an IEE is beneficial and relevant to their careers. Further, Extension educators…

40 CFR 52.1478 - Extensions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Extensions. 52.1478 Section 52.1478... PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Nevada § 52.1478 Extensions. The Administrator, by the... carbon monoxide nonattainment area. [61 FR 57333, Nov. 6, 1996] ...

40 CFR 52.1478 - Extensions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 4 2013-07-01 2013-07-01 false Extensions. 52.1478 Section 52.1478... PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Nevada § 52.1478 Extensions. The Administrator, by the... carbon monoxide nonattainment area. [61 FR 57333, Nov. 6, 1996] ...

40 CFR 52.1478 - Extensions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 4 2014-07-01 2014-07-01 false Extensions. 52.1478 Section 52.1478... PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Nevada § 52.1478 Extensions. The Administrator, by the... carbon monoxide nonattainment area. [61 FR 57333, Nov. 6, 1996] ...

40 CFR 52.1478 - Extensions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 4 2011-07-01 2011-07-01 false Extensions. 52.1478 Section 52.1478... PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Nevada § 52.1478 Extensions. The Administrator, by the... carbon monoxide nonattainment area. [61 FR 57333, Nov. 6, 1996] ...

40 CFR 52.1478 - Extensions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 4 2012-07-01 2012-07-01 false Extensions. 52.1478 Section 52.1478... PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Nevada § 52.1478 Extensions. The Administrator, by the... carbon monoxide nonattainment area. [61 FR 57333, Nov. 6, 1996] ...

Delivering Extension to the Living Room Using Internet TV

ERIC Educational Resources Information Center

Rice, Grant G., III

2014-01-01

Television is a widely adopted source for viewing educational information. Unfortunately, producing a television show on network television can be costly and time consuming. Internet TV offers Extension video content producers the opportunity to create a niche topic channel quickly and at low cost. Internet TV offers viewers a low-cost and…

34 CFR 101.42 - Extension of time or postponement.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 1 2010-07-01 2010-07-01 false Extension of time or postponement. 101.42 Section 101.42 Education Regulations of the Offices of the Department of Education OFFICE FOR CIVIL RIGHTS... set forth the reasons for the application. Applications may be granted upon a showing of good cause by...

11 CFR 100.55 - Extension of credit.

Code of Federal Regulations, 2010 CFR

2010-01-01

... substantially similar to extensions of credit to nonpolitical debtors that are of similar risk and size of... 11 Federal Elections 1 2010-01-01 2010-01-01 false Extension of credit. 100.55 Section 100.55... Contribution (2 U.S.C. 431(8)) § 100.55 Extension of credit. The extension of credit by any person is a...

Changes in cis-regulatory elements of a key floral regulator are associated with divergence of inflorescence architectures.

PubMed

Kusters, Elske; Della Pina, Serena; Castel, Rob; Souer, Erik; Koes, Ronald

2015-08-15

Higher plant species diverged extensively with regard to the moment (flowering time) and position (inflorescence architecture) at which flowers are formed. This seems largely caused by variation in the expression patterns of conserved genes that specify floral meristem identity (FMI), rather than changes in the encoded proteins. Here, we report a functional comparison of the promoters of homologous FMI genes from Arabidopsis, petunia, tomato and Antirrhinum. Analysis of promoter-reporter constructs in petunia and Arabidopsis, as well as complementation experiments, showed that the divergent expression of leafy (LFY) and the petunia homolog aberrant leaf and flower (ALF) results from alterations in the upstream regulatory network rather than cis-regulatory changes. The divergent expression of unusual floral organs (UFO) from Arabidopsis, and the petunia homolog double top (DOT), however, is caused by the loss or gain of cis-regulatory promoter elements, which respond to trans-acting factors that are expressed in similar patterns in both species. Introduction of pUFO:UFO causes no obvious defects in Arabidopsis, but in petunia it causes the precocious and ectopic formation of flowers. This provides an example of how a change in a cis-regulatory region can account for a change in the plant body plan. © 2015. Published by The Company of Biologists Ltd.

77 FR 29690 - Extension of a Currently Approved Collection; Comments Requested; COPS Extension Request Form

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-18

... DEPARTMENT OF JUSTICE Agency Information Collection Activities [OMB Number 1103-0093] Extension of a Currently Approved Collection; Comments Requested; COPS Extension Request Form ACTION: 30-Day Notice of Information Collection Under Review. The Department of Justice (DOJ) Office of Community...

Machine-learning-based classification of real-time tissue elastography for hepatic fibrosis in patients with chronic hepatitis B.

PubMed

Chen, Yang; Luo, Yan; Huang, Wei; Hu, Die; Zheng, Rong-Qin; Cong, Shu-Zhen; Meng, Fan-Kun; Yang, Hong; Lin, Hong-Jun; Sun, Yan; Wang, Xiu-Yan; Wu, Tao; Ren, Jie; Pei, Shu-Fang; Zheng, Ying; He, Yun; Hu, Yu; Yang, Na; Yan, Hongmei

2017-10-01

Hepatic fibrosis is a common middle stage of the pathological processes of chronic liver diseases. Clinical intervention during the early stages of hepatic fibrosis can slow the development of liver cirrhosis and reduce the risk of developing liver cancer. Performing a liver biopsy, the gold standard for viral liver disease management, has drawbacks such as invasiveness and a relatively high sampling error rate. Real-time tissue elastography (RTE), one of the most recently developed technologies, might be promising imaging technology because it is both noninvasive and provides accurate assessments of hepatic fibrosis. However, determining the stage of liver fibrosis from RTE images in a clinic is a challenging task. In this study, in contrast to the previous liver fibrosis index (LFI) method, which predicts the stage of diagnosis using RTE images and multiple regression analysis, we employed four classical classifiers (i.e., Support Vector Machine, Naïve Bayes, Random Forest and K-Nearest Neighbor) to build a decision-support system to improve the hepatitis B stage diagnosis performance. Eleven RTE image features were obtained from 513 subjects who underwent liver biopsies in this multicenter collaborative research. The experimental results showed that the adopted classifiers significantly outperformed the LFI method and that the Random Forest(RF) classifier provided the highest average accuracy among the four machine algorithms. This result suggests that sophisticated machine-learning methods can be powerful tools for evaluating the stage of hepatic fibrosis and show promise for clinical applications. Copyright © 2017 Elsevier Ltd. All rights reserved.

40 CFR 52.691 - Extensions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Extensions. 52.691 Section 52.691 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Idaho § 52.691 Extensions. (a) The Administrator, by authority delegated...

26. Photocopy of 1921 architectural drawing titled: BUILDING 59, EXTENSION ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

26. Photocopy of 1921 architectural drawing titled: BUILDING 59, EXTENSION NORTH, ELEVATIONS showing east and west elevations of the 1922 north section of Building 59. Drawing No. 6270, File No. 651-23. - Puget Sound Naval Shipyard, Pattern Shop, Farragut Avenue, Bremerton, Kitsap County, WA

40 CFR 52.2472 - Extensions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 4 2011-07-01 2011-07-01 false Extensions. 52.2472 Section 52.2472... PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Washington § 52.2472 Extensions. The Administrator, by... (until December 31, 1995) the attainment date for the Spokane, Washington, PM-10 nonattainment area and...

40 CFR 52.2472 - Extensions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Extensions. 52.2472 Section 52.2472... PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Washington § 52.2472 Extensions. The Administrator, by... (until December 31, 1995) the attainment date for the Spokane, Washington, PM-10 nonattainment area and...

40 CFR 52.2472 - Extensions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 5 2013-07-01 2013-07-01 false Extensions. 52.2472 Section 52.2472... PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Washington § 52.2472 Extensions. The Administrator, by... (until December 31, 1995) the attainment date for the Spokane, Washington, PM-10 nonattainment area and...

40 CFR 52.2472 - Extensions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 5 2014-07-01 2014-07-01 false Extensions. 52.2472 Section 52.2472... PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Washington § 52.2472 Extensions. The Administrator, by... (until December 31, 1995) the attainment date for the Spokane, Washington, PM-10 nonattainment area and...

40 CFR 52.2472 - Extensions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 5 2012-07-01 2012-07-01 false Extensions. 52.2472 Section 52.2472... PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Washington § 52.2472 Extensions. The Administrator, by... (until December 31, 1995) the attainment date for the Spokane, Washington, PM-10 nonattainment area and...

Extension Specialists: A Self-Analysis.

ERIC Educational Resources Information Center

Gerber, John M.

1985-01-01

To document perceived changes in the role of the extension horticulture specialist, a national survey of state horticulture specialists was conducted in 1983. Extension specialists in horticulture appear to be moving away from the traditional activities of farm visits and personal interaction with individual producers. (CT)

Predicting the Extension of Biomedical Ontologies

PubMed Central

Pesquita, Catia; Couto, Francisco M.

2012-01-01

Developing and extending a biomedical ontology is a very demanding task that can never be considered complete given our ever-evolving understanding of the life sciences. Extension in particular can benefit from the automation of some of its steps, thus releasing experts to focus on harder tasks. Here we present a strategy to support the automation of change capturing within ontology extension where the need for new concepts or relations is identified. Our strategy is based on predicting areas of an ontology that will undergo extension in a future version by applying supervised learning over features of previous ontology versions. We used the Gene Ontology as our test bed and obtained encouraging results with average f-measure reaching 0.79 for a subset of biological process terms. Our strategy was also able to outperform state of the art change capturing methods. In addition we have identified several issues concerning prediction of ontology evolution, and have delineated a general framework for ontology extension prediction. Our strategy can be applied to any biomedical ontology with versioning, to help focus either manual or semi-automated extension methods on areas of the ontology that need extension. PMID:23028267

Caloric Restriction-Induced Extension of Chronological Lifespan Requires Intact Respiration in Budding Yeast.

PubMed

Kwon, Young-Yon; Lee, Sung-Keun; Lee, Cheol-Koo

2017-04-01

Caloric restriction (CR) has been shown to extend lifespan and prevent cellular senescence in various species ranging from yeast to humans. Many effects of CR may contribute to extend lifespan. Specifically, CR prevents oxidative damage from reactive oxygen species (ROS) by enhancing mitochondrial function. In this study, we characterized 33 single electron transport chain (ETC) gene-deletion strains to identify CR-induced chronological lifespan (CLS) extension mechanisms. Interestingly, defects in 17 of these 33 ETC gene-deleted strains showed loss of both respiratory function and CR-induced CLS extension. On the contrary, the other 16 respiration-capable mutants showed increased CLS upon CR along with increased mitochondrial membrane potential (MMP) and intracellular adenosine triphosphate (ATP) levels, with decreased mitochondrial superoxide generation. We measured the same parameters in the 17 non-respiratory mutants upon CR. CR simultaneously increased MMP and mitochondrial superoxide generation without altering intracellular ATP levels. In conclusion, respiration is essential for CLS extension by CR and is important for balancing MMP, ROS, and ATP levels.

Upper Stage Engine Composite Nozzle Extensions

NASA Technical Reports Server (NTRS)

Valentine, Peter G.; Allen, Lee R.; Gradl, Paul R.; Greene, Sandra E.; Sullivan, Brian J.; Weller, Leslie J.; Koenig, John R.; Cuneo, Jacques C.; Thompson, James; Brown, Aaron;

40 CFR 52.1572 - Extensions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 4 2014-07-01 2014-07-01 false Extensions. 52.1572 Section 52.1572... PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) New Jersey § 52.1572 Extensions. Pursuant to section 186(a)(4... Consolidated Metropolitan Statistical Carbon Monoxide nonattainment area. [61 FR 56900, Nov. 5, 1996] ...

40 CFR 52.1572 - Extensions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 4 2013-07-01 2013-07-01 false Extensions. 52.1572 Section 52.1572... PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) New Jersey § 52.1572 Extensions. Pursuant to section 186(a)(4... Consolidated Metropolitan Statistical Carbon Monoxide nonattainment area. [61 FR 56900, Nov. 5, 1996] ...

40 CFR 52.1672 - Extensions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 4 2014-07-01 2014-07-01 false Extensions. 52.1672 Section 52.1672... PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) New York § 52.1672 Extensions. Pursuant to section 186(a)(4... Consolidated Metropolitan Statistical Carbon Monoxide nonattainment area. [61 FR 56900, Nov. 5, 1996] ...

40 CFR 52.322 - Extensions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 3 2014-07-01 2014-07-01 false Extensions. 52.322 Section 52.322... PROMULGATION OF IMPLEMENTATION PLANS Colorado § 52.322 Extensions. The Administrator, by authority delegated..., 1995) the attainment date for the Denver, Colorado, PM-10 nonattainment area. [60 FR 52315, Oct. 6...

40 CFR 52.1572 - Extensions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 4 2011-07-01 2011-07-01 false Extensions. 52.1572 Section 52.1572... PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) New Jersey § 52.1572 Extensions. Pursuant to section 186(a)(4... Consolidated Metropolitan Statistical Carbon Monoxide nonattainment area. [61 FR 56900, Nov. 5, 1996] ...

40 CFR 52.1672 - Extensions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 4 2013-07-01 2013-07-01 false Extensions. 52.1672 Section 52.1672... PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) New York § 52.1672 Extensions. Pursuant to section 186(a)(4... Consolidated Metropolitan Statistical Carbon Monoxide nonattainment area. [61 FR 56900, Nov. 5, 1996] ...

40 CFR 52.1572 - Extensions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 4 2012-07-01 2012-07-01 false Extensions. 52.1572 Section 52.1572... PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) New Jersey § 52.1572 Extensions. Pursuant to section 186(a)(4... Consolidated Metropolitan Statistical Carbon Monoxide nonattainment area. [61 FR 56900, Nov. 5, 1996] ...

40 CFR 52.322 - Extensions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 3 2011-07-01 2011-07-01 false Extensions. 52.322 Section 52.322... PROMULGATION OF IMPLEMENTATION PLANS Colorado § 52.322 Extensions. The Administrator, by authority delegated..., 1995) the attainment date for the Denver, Colorado, PM-10 nonattainment area. [60 FR 52315, Oct. 6...

40 CFR 52.322 - Extensions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 3 2012-07-01 2012-07-01 false Extensions. 52.322 Section 52.322... PROMULGATION OF IMPLEMENTATION PLANS Colorado § 52.322 Extensions. The Administrator, by authority delegated..., 1995) the attainment date for the Denver, Colorado, PM-10 nonattainment area. [60 FR 52315, Oct. 6...

40 CFR 52.1672 - Extensions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 4 2011-07-01 2011-07-01 false Extensions. 52.1672 Section 52.1672... PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) New York § 52.1672 Extensions. Pursuant to section 186(a)(4... Consolidated Metropolitan Statistical Carbon Monoxide nonattainment area. [61 FR 56900, Nov. 5, 1996] ...

40 CFR 52.1572 - Extensions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Extensions. 52.1572 Section 52.1572... PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) New Jersey § 52.1572 Extensions. Pursuant to section 186(a)(4... Consolidated Metropolitan Statistical Carbon Monoxide nonattainment area. [61 FR 56900, Nov. 5, 1996] ...

40 CFR 52.322 - Extensions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 3 2013-07-01 2013-07-01 false Extensions. 52.322 Section 52.322... PROMULGATION OF IMPLEMENTATION PLANS Colorado § 52.322 Extensions. The Administrator, by authority delegated..., 1995) the attainment date for the Denver, Colorado, PM-10 nonattainment area. [60 FR 52315, Oct. 6...

40 CFR 52.322 - Extensions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Extensions. 52.322 Section 52.322... PROMULGATION OF IMPLEMENTATION PLANS Colorado § 52.322 Extensions. The Administrator, by authority delegated..., 1995) the attainment date for the Denver, Colorado, PM-10 nonattainment area. [60 FR 52315, Oct. 6...

40 CFR 52.1672 - Extensions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 4 2012-07-01 2012-07-01 false Extensions. 52.1672 Section 52.1672... PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) New York § 52.1672 Extensions. Pursuant to section 186(a)(4... Consolidated Metropolitan Statistical Carbon Monoxide nonattainment area. [61 FR 56900, Nov. 5, 1996] ...

Extensions under development for the HEVC standard

NASA Astrophysics Data System (ADS)

Sullivan, Gary J.

2013-09-01

This paper discusses standardization activities for extending the capabilities of the High Efficiency Video Coding (HEVC) standard - the first edition of which was completed in early 2013. These near-term extensions are focused on three areas: range extensions (such as enhanced chroma formats, monochrome video, and increased bit depth), bitstream scalability extensions for spatial and fidelity scalability, and 3D video extensions (including stereoscopic/multi-view coding, and probably also depth map coding and combinations thereof). Standardization extensions on each of these topics will be completed by mid-2014, and further work beyond that timeframe is also discussed.

Parallel Extension Tectonics (PET): Early Cretaceous tectonic extension of the Eastern Eurasian continent

NASA Astrophysics Data System (ADS)

Liu, Junlai; Ji, Mo; Ni, Jinlong; Guan, Huimei; Shen, Liang

2017-04-01

The present study reports progress of our recent studies on the extensional structures in eastern North China craton and contiguous areas. We focus on characterizing and timing the formation/exhumation of the extensional structures, the Liaonan metamorphic core complex (mcc) and the Dayingzi basin from the Liaodong peninsula, the Queshan mcc, the Wulian mcc and the Zhucheng basin from the Jiaodong peninsula, and the Dashan magmatic dome within the Sulu orogenic belt. Magmatic rocks (either volcanic or plutonic) are ubiquitous in association with the tectonic extension (both syn- and post-kinematic). Evidence for crustal-mantle magma mixing are popular in many syn-kinematic intrusions. Geochemical analysis reveals that basaltic, andesitic to rhyolitic magmas were generated during the tectonic extension. Sr-Nd isotopes of the syn-kinematic magmatic rocks suggest that they were dominantly originated from ancient or juvenile crust partly with mantle signatures. Post-kinematic mafic intrusions with ages from ca. 121 Ma to Cenozoic, however, are of characteristic oceanic island basalts (OIB)-like trace element distribution patterns and relatively depleted radiogenic Sr-Nd isotope compositions. Integrated studies on the extensional structures, geochemical signatures of syn-kinematic magmatic rocks (mostly of granitic) and the tectono-magmatic relationships suggest that extension of the crust and the mantle lithosphere triggered the magmatisms from both the crust and the mantle. The Early Cretaceous tectono-magmatic evolution of the eastern Eurasian continent is governed by the PET in which the tectonic processes is subdivided into two stages, i.e. an early stage of tectonic extension, and a late stage of collapse of the extended lithosphere and transformation of lithospheric mantle. During the early stage, tectonic extension of the lithosphere led to detachment faulting in both the crust and mantle, resulted in the loss of some of the subcontinental roots, gave rise to

A STUDY OF COUNTY COMMISSIONERS' PRECEPTION OF THE NORTH CAROLINA COOPERATIVE EXTENSION SERVICE, NORTHEASTERN EXTENSION DISTRICT, NORTH CAROLINA.

ERIC Educational Resources Information Center

WHITE, ESTELLE EDWARDS

AN INTERVIEW QUESTIONNAIRE WAS USED TO DISCOVER HOW 85 ELECTED COUNTY COMMISSIONERS IN THE NORTHEASTERN EXTENSION DISTRICT OF NORTH CAROLINA PERCEIVED THE COOPERATIVE EXTENSION SERVICE. THE EXTENT TO WHICH TENURE AS A COMMISSIONER, OCCUPATION, EDUCATION, AGE, AND INVOLVEMENT IN EXTENSION ACTIVITIES WERE ASSOCIATED WITH THE PERCEPTION OF…

Extensive Nevus Comedonicus, Complicated with Recurrent Abscesses, Successfully Treated with Surgical Resurfacing.

PubMed

Manikavachakan, Narender; Siddaraju, Maheshwari Nallur; Rajendran, Sarangapani Chakrapani; Venkataraman, Aniketh

2018-01-01

Nevus comedonicus is a rare epidermal abnormality of the pilosebaceous unit, which is congenital in most patients but may also appear early in childhood. It may be localized or have an extensive involvement, the latter showing a unilateral predominance with only a few cases presenting bilaterally. Extensive nevus comedonicus can be associated with musculoskeletal defects, eye and neurological involvement, which constitutes nevus comedonicus syndrome. Uncomplicated nevus comedonicus can be treated with topical keratolytics, diode, erbium laser, and ultrapulse CO 2 laser. Surgical excision can be performed to ensure complete removal and nonrecurrence. This case report refers to a young male patient with extensive nevus comedonicus present over left chest, left axilla, and left upper back without systemic involvement, treated with staged surgical excision and resurfacing.

Repeat Customer Success in Extension

ERIC Educational Resources Information Center

Bess, Melissa M.; Traub, Sarah M.

2013-01-01

Four multi-session research-based programs were offered by two Extension specialist in one rural Missouri county. Eleven participants who came to multiple Extension programs could be called "repeat customers." Based on the total number of participants for all four programs, 25% could be deemed as repeat customers. Repeat customers had…

40 CFR 52.691 - Extensions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 3 2014-07-01 2014-07-01 false Extensions. 52.691 Section 52.691... PROMULGATION OF IMPLEMENTATION PLANS Idaho § 52.691 Extensions. (a) The Administrator, by authority delegated... December 31, 1995) the attainment date for the Power-Bannock Counties PM-10 nonattainment area and the...

40 CFR 52.2322 - Extensions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 5 2012-07-01 2012-07-01 false Extensions. 52.2322 Section 52.2322... PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Utah § 52.2322 Extensions. (a) The Administrator, by authority... December 31, 1995) the attainment date for the Salt Lake County PM10 nonattainment area. The Administrator...

40 CFR 52.2322 - Extensions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 4 2011-07-01 2011-07-01 false Extensions. 52.2322 Section 52.2322... PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Utah § 52.2322 Extensions. (a) The Administrator, by authority... December 31, 1995) the attainment date for the Salt Lake County PM10 nonattainment area. The Administrator...

40 CFR 52.2322 - Extensions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Extensions. 52.2322 Section 52.2322... PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Utah § 52.2322 Extensions. (a) The Administrator, by authority... December 31, 1995) the attainment date for the Salt Lake County PM10 nonattainment area. The Administrator...

40 CFR 52.691 - Extensions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 3 2012-07-01 2012-07-01 false Extensions. 52.691 Section 52.691... PROMULGATION OF IMPLEMENTATION PLANS Idaho § 52.691 Extensions. (a) The Administrator, by authority delegated... December 31, 1995) the attainment date for the Power-Bannock Counties PM-10 nonattainment area and the...

40 CFR 52.82 - Extensions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 3 2011-07-01 2011-07-01 false Extensions. 52.82 Section 52.82... PROMULGATION OF IMPLEMENTATION PLANS Alaska § 52.82 Extensions. The Administrator, by authority delegated under..., 1996) the attainment date for the MOA, Alaska CO nonattainment area. [61 FR 33678, June 28, 1996] ...

40 CFR 52.2322 - Extensions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 5 2014-07-01 2014-07-01 false Extensions. 52.2322 Section 52.2322... PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Utah § 52.2322 Extensions. (a) The Administrator, by authority... December 31, 1995) the attainment date for the Salt Lake County PM10 nonattainment area. The Administrator...

40 CFR 52.691 - Extensions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 3 2013-07-01 2013-07-01 false Extensions. 52.691 Section 52.691... PROMULGATION OF IMPLEMENTATION PLANS Idaho § 52.691 Extensions. (a) The Administrator, by authority delegated... December 31, 1995) the attainment date for the Power-Bannock Counties PM-10 nonattainment area and the...

40 CFR 52.2322 - Extensions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 5 2013-07-01 2013-07-01 false Extensions. 52.2322 Section 52.2322... PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Utah § 52.2322 Extensions. (a) The Administrator, by authority... December 31, 1995) the attainment date for the Salt Lake County PM10 nonattainment area. The Administrator...

40 CFR 52.532 - Extensions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 3 2012-07-01 2012-07-01 false Extensions. 52.532 Section 52.532... PROMULGATION OF IMPLEMENTATION PLANS Florida § 52.532 Extensions. (a) The Administrator hereby extends for 18... areas (40 CFR 81.310). [45 FR 2033, Jan. 10, 1980; 45 FR 28112, Apr. 28, 1980] ...

40 CFR 52.82 - Extensions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 3 2012-07-01 2012-07-01 false Extensions. 52.82 Section 52.82... PROMULGATION OF IMPLEMENTATION PLANS Alaska § 52.82 Extensions. The Administrator, by authority delegated under..., 1996) the attainment date for the MOA, Alaska CO nonattainment area. [61 FR 33678, June 28, 1996] ...

40 CFR 52.82 - Extensions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 3 2014-07-01 2014-07-01 false Extensions. 52.82 Section 52.82... PROMULGATION OF IMPLEMENTATION PLANS Alaska § 52.82 Extensions. The Administrator, by authority delegated under..., 1996) the attainment date for the MOA, Alaska CO nonattainment area. [61 FR 33678, June 28, 1996] ...

40 CFR 52.82 - Extensions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Extensions. 52.82 Section 52.82... PROMULGATION OF IMPLEMENTATION PLANS Alaska § 52.82 Extensions. The Administrator, by authority delegated under..., 1996) the attainment date for the MOA, Alaska CO nonattainment area. [61 FR 33678, June 28, 1996] ...

40 CFR 52.82 - Extensions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 3 2013-07-01 2013-07-01 false Extensions. 52.82 Section 52.82... PROMULGATION OF IMPLEMENTATION PLANS Alaska § 52.82 Extensions. The Administrator, by authority delegated under..., 1996) the attainment date for the MOA, Alaska CO nonattainment area. [61 FR 33678, June 28, 1996] ...

40 CFR 52.532 - Extensions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 3 2013-07-01 2013-07-01 false Extensions. 52.532 Section 52.532... PROMULGATION OF IMPLEMENTATION PLANS Florida § 52.532 Extensions. (a) The Administrator hereby extends for 18... areas (40 CFR 81.310). [45 FR 2033, Jan. 10, 1980; 45 FR 28112, Apr. 28, 1980] ...

40 CFR 52.532 - Extensions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Extensions. 52.532 Section 52.532... PROMULGATION OF IMPLEMENTATION PLANS Florida § 52.532 Extensions. (a) The Administrator hereby extends for 18... areas (40 CFR 81.310). [45 FR 2033, Jan. 10, 1980; 45 FR 28112, Apr. 28, 1980] ...

Boiler-turbine life extension

DOE Office of Scientific and Technical Information (OSTI.GOV)

Natzkov, S.; Nikolov, M.

1995-12-01

The design life of the main power equipment-boilers and turbines is about 105 working hours. The possibilities for life extension are after normatively regulated control tests. The diagnostics and methodology for Boilers and Turbines Elements Remaining Life Assessment using up to date computer programs, destructive and nondestructive control of metal of key elements of units equipment, metal creep and low cycle fatigue calculations. As well as data for most common damages and some technical decisions for elements life extension are presented.

Extension Handbook. Processes and Practices. Second Edition.

ERIC Educational Resources Information Center

Blackburn, Donald J., Ed.

This book contains the following papers about processes and practices in extension education in Canada: "Historical Roots" (Blackburn, Flaherty); "Transitions and Directions in Extension" (Blackburn, Flaherty); "Applying Learning Theory in Extension Work" (Griffith); "Understanding and Applying Motivation…

AGRICULTURAL EXTENSION.

ERIC Educational Resources Information Center

FARQUHAR, R.N.

AUSTRALIAN AGRICULTURAL EXTENSION HAS LONG EMPHASIZED TECHNICAL ADVISORY SERVICE AT THE EXPENSE OF THE SOCIOECONOMIC ASPECTS OF FARM PRODUCTION AND FARM LIFE. ONLY IN TASMANIA HAS FARM MANAGEMENT BEEN STRESSED. DEMANDS FOR THE WHOLE-FARM APPROACH HAVE PRODUCED A TREND TOWARD GENERALISM FOR DISTRICT OFFICERS IN MOST STATES. THE FEDERAL GOVERNMENT,…

40 CFR 52.1376 - Extensions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 4 2014-07-01 2014-07-01 false Extensions. 52.1376 Section 52.1376... PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Montana § 52.1376 Extensions. On October 7, 1993, EPA granted... 1990, for submittal of the SIP for the East Helena area to attain and maintain the sulfur dioxide...

40 CFR 52.1376 - Extensions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 4 2013-07-01 2013-07-01 false Extensions. 52.1376 Section 52.1376... PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Montana § 52.1376 Extensions. On October 7, 1993, EPA granted... 1990, for submittal of the SIP for the East Helena area to attain and maintain the sulfur dioxide...

40 CFR 52.1376 - Extensions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 4 2011-07-01 2011-07-01 false Extensions. 52.1376 Section 52.1376... PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Montana § 52.1376 Extensions. On October 7, 1993, EPA granted... 1990, for submittal of the SIP for the East Helena area to attain and maintain the sulfur dioxide...

40 CFR 52.1376 - Extensions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Extensions. 52.1376 Section 52.1376... PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Montana § 52.1376 Extensions. On October 7, 1993, EPA granted... 1990, for submittal of the SIP for the East Helena area to attain and maintain the sulfur dioxide...

40 CFR 52.1376 - Extensions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 4 2012-07-01 2012-07-01 false Extensions. 52.1376 Section 52.1376... PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Montana § 52.1376 Extensions. On October 7, 1993, EPA granted... 1990, for submittal of the SIP for the East Helena area to attain and maintain the sulfur dioxide...

Extensive Reading Coursebooks in China

ERIC Educational Resources Information Center

Renandya, Willy A.; Hu, Guangwei; Xiang, Yu

2015-01-01

This article reports on a principle-based evaluation of eight dedicated extensive reading coursebooks published in mainland China and used in many universities across the country. The aim is to determine the extent to which these coursebooks reflect a core set of nine second language acquisition and extensive reading principles. Our analysis shows…

Special Section: Extension in a Global Context.

ERIC Educational Resources Information Center

Rosson, C. Parr, III; And Others

1991-01-01

"International Programming Issues for Extension Education" (Rosson, Sanders) describes a survey of extension personnel identifying global competition and agriculture as a key issue. "Expanding Our Horizons Internationally" (Richardson, Woods) discusses North Carolina Extension's staff development on global issues. In…

Self-excited electrostatic pendulum showing electrohydrodynamic-force-induced oscillation

NASA Astrophysics Data System (ADS)

Stephan, Karl D.; Hernandez Guerrero, José M.

2017-12-01

The electrohydrodynamic (EHD) effect ("ion wind") associated with corona discharges in air has been extensively investigated and modeled. We present a simple experiment that shows how both the magnitude and direction of EHD forces can change in such a way as to impart energy continuously to an oscillating electrostatic pendulum. The amplitude of oscillations of an electrostatic pendulum subject to EHD forces can grow approximately exponentially over a period of minutes, and we describe a qualitative theory to account for this effect, along with implications of these experiments for theories of ball lightning.

Fruit regulates seasonal expression of flowering genes in alternate-bearing ‘Moncada’ mandarin

PubMed Central

Muñoz-Fambuena, Natalia; Mesejo, Carlos; Carmen González-Mas, M.; Primo-Millo, Eduardo; Agustí, Manuel; Iglesias, Domingo J.

2011-01-01

Background and Aims The presence of fruit has been widely reported to act as an inhibitor of flowering in fruit trees. This study is an investigation into the effect of fruit load on flowering of ‘Moncada’ mandarin and on the expression of putative orthologues of genes involved in flowering pathways to provide insight into the molecular mechanisms underlying alternate bearing in citrus. Methods The relationship between fruit load and flowering intensity was examined first. Defruiting experiments were further conducted to demonstrate the causal effect of fruit removal upon flowering. Finally, the activity of flowering-related genes was investigated to determine the extent to which their seasonal expression is affected by fruit yield. Key Results First observations and defruiting experiments indicated a significant inverse relationship between preceding fruit load and flowering intensity. Moreover, data indicated that when fruit remained on the tree from November onwards, a dramatic inhibition of flowering occurred the following spring. The study of the expression pattern of flowering-genes of on (fully loaded) and off (without fruits) trees revealed that homologues of FLOWERING LOCUS T (FT), SUPRESSOR OF OVEREXPRESSION OF CONSTANS 1 (SOC1), APETALA1 (AP1) and LEAFY (LFY) were negatively affected by fruit load. Thus, CiFT expression showed a progressive increase in leaves from off trees through the study period, the highest differences found from December onwards (10-fold). Whereas differences in the relative expression of SOC1 only reached significance from September to mid-December, CsAP1 expression was constantly higher in those trees through the whole study period. Significant variations in CsLFY expression only were found in late February (close to 20 %). On the other hand, the expression of the homologues of TERMINAL FLOWER 1 (TFL1) and FLOWERING LOCUS C (FLC) did not appear to be related to fruit load. Conclusions These results suggest for the first time

78 FR 9901 - Agency Information Collection Extension

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-12

... DEPARTMENT OF ENERGY Agency Information Collection Extension AGENCY: Department of Energy. ACTION... Energy (DOE) has submitted an information collection request to the OMB for extension under the provisions of the Paperwork Reduction Act of 1995. The information collection requests a three-year extension...

75 FR 4055 - Agency Information Collection Extension

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-26

... DEPARTMENT OF ENERGY Agency Information Collection Extension AGENCY: Department of Energy. ACTION... Energy (DOE) has submitted an information collection request to the OMB for extension under the provisions of the Paperwork Reduction Act of 1995. The information collection requests a three-year extension...

78 FR 38305 - Agency Information Collection Extension

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-26

... DEPARTMENT OF ENERGY Agency Information Collection Extension AGENCY: Department of Energy. ACTION... Energy (DOE) has submitted an information collection request to the OMB for extension under the provisions of the Paperwork Reduction Act of 1995. The information collection requests a three-year extension...

Tsallis non-extensive statistics and solar wind plasma complexity

NASA Astrophysics Data System (ADS)

Pavlos, G. P.; Iliopoulos, A. C.; Zastenker, G. N.; Zelenyi, L. M.; Karakatsanis, L. P.; Riazantseva, M. O.; Xenakis, M. N.; Pavlos, E. G.

2015-03-01

This article presents novel results revealing non-equilibrium phase transition processes in the solar wind plasma during a strong shock event, which took place on 26th September 2011. Solar wind plasma is a typical case of stochastic spatiotemporal distribution of physical state variables such as force fields (B → , E →) and matter fields (particle and current densities or bulk plasma distributions). This study shows clearly the non-extensive and non-Gaussian character of the solar wind plasma and the existence of multi-scale strong correlations from the microscopic to the macroscopic level. It also underlines the inefficiency of classical magneto-hydro-dynamic (MHD) or plasma statistical theories, based on the classical central limit theorem (CLT), to explain the complexity of the solar wind dynamics, since these theories include smooth and differentiable spatial-temporal functions (MHD theory) or Gaussian statistics (Boltzmann-Maxwell statistical mechanics). On the contrary, the results of this study indicate the presence of non-Gaussian non-extensive statistics with heavy tails probability distribution functions, which are related to the q-extension of CLT. Finally, the results of this study can be understood in the framework of modern theoretical concepts such as non-extensive statistical mechanics (Tsallis, 2009), fractal topology (Zelenyi and Milovanov, 2004), turbulence theory (Frisch, 1996), strange dynamics (Zaslavsky, 2002), percolation theory (Milovanov, 1997), anomalous diffusion theory and anomalous transport theory (Milovanov, 2001), fractional dynamics (Tarasov, 2013) and non-equilibrium phase transition theory (Chang, 1992).

Preparing Students for Extension Careers and Expanding U.S. Extension Reach through International Service Learning

ERIC Educational Resources Information Center

Ebner, Paul; Constantinescu, Alina; Borlea, Florian; Indrea, Alexandru; Russell, Mark

2017-01-01

As U.S. Extension broadens its reach around the globe, an increased need exists for Extension professionals who have not only technical knowledge but also the cultural competencies to apply that knowledge in international settings. We describe a course that provides students with the opportunity to develop skills needed for potential careers in…

Extensive subclinical sinusitis leading to Moraxella osloensis meningitis.

PubMed

Fox-Lewis, A; Coltart, G; Rice, S; Sen, R; Gourtsoyannis, Y; Hyare, H; Gupta, R K

2016-01-01

We report a case of a 31 year old male with extensive subclinical sinusitis leading to erosion in the cribriform plate and subsequent meningitis caused by the organism Moraxella osloensis . The patient presented to the emergency department with rapid onset confusion, neck stiffness and headache. Inflammatory markers, renal and liver function, and a chest radiograph were all normal. CT Head showed extensive polyp disease in the paranasal sinuses with expansion of the left frontal sinus and CT Sinuses revealed an area of low attenuation in the cribriform plate consistent with bony erosion. MRI Head showed thick loculated sinus inflammation. Lumbar puncture yielded CSF with a high white cell count of predominantly mononuclear cells, no visible organisms and an elevated protein. CSF microscopy, culture and viral PCR were not diagnostic, and so the CSF was sent for 16S rDNA PCR screening, which identified the rDNA of Moraxella osloensis . Moraxella osloensis is a rare cause of bacterial meningitis, with only a few reported cases. This case illustrates that sinusitis, while a common condition, when severe can predispose to intracranial infection with atypical and low virulence organisms such as Moraxella species, which do not commonly cause invasive CNS disease. This case represents the first case of Moraxella osloensis meningitis reported from the United Kingdom.

Late Quaternary Arc-parallel Extension of the Kongur Extensional System (KES), Chinese Pamir

NASA Astrophysics Data System (ADS)

Chen, J.; Schoenbohm, L. M.; Owen, L. A.; Li, W.; Yuan, Z.; Li, T.; Robinson, A. C.; Sobel, E. R.; Caffee, M. W.

2016-12-01

Recent normal and strike-slip faulting on the Pamir Plateau of the NW Tibetan Plateau has been linked to synorogenic extension, radial thrusting or oroclinal bending, or northward propagation of the Karakorum fault from its southern segment. Clearly the precise driver remains poorly understood. The 250 km long Kongur Extensional System (KES) lies along the northeastern margin of the Pamir at the western end of the Himalayan-Tibetan orogenic belt, and is part of a regional fault system, which accommodates east-west extension in the hanging wall of the active Main Pamir Thrust (MPT).To better understand the nature of extension in the Pamir and to test the existing models, late Quaternary slip rate along the KES need to be defined. We employ geomorphic mapping, dGPS surveying, and 10Be surface exposure and depth profile dating to quantify rates of fault slip using offset outwash terraces, landslides, and moraines at ten sites as strain markers to identify spatial patterns in deformation rate along the KES. Field mapping and kinematic analysis across offset features show that the overall extension direction is subhorizontal, oriented E-W.A systematic north to south decrease in late Quaternary slip magnitude and rate along the KES from 7 mm/yr at Muji to the north to less than 1 mm/yr at Dabudaer to the south. These geologic rates are consistent with geodetic rates determined by GPS data. All available geologic and geodetic data clearly show that the KES is an independent structure which accommodates east-west extension between the west Pamir Plateau and east Pamir-Tarim basin, and is not kinematically linked with the northern Karakoram fault. Recent extension of the KES is arc-parallel and likely relates to the collision between the Pamir and Tian Shan along longitude E74.4 and clockwise rotation of Tarim block.

77 FR 23469 - Agency Information Collection Extension

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-19

... DEPARTMENT OF ENERGY Agency Information Collection Extension AGENCY: U.S. Department of Energy... Department of Energy (DOE) has submitted an information collection request to OMB for extension under the provisions of the Paperwork Reduction Act of 1995. The information collection requests a three-year extension...

77 FR 44602 - Agency Information Collection Extension

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-30

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78 FR 66909 - Agency Information Collection Extension

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-07

... DEPARTMENT OF ENERGY Agency Information Collection Extension AGENCY: U.S. Department of Energy... Department of Energy (DOE) has previously published its Agency Information Collection Extension request in... collection request to the OMB for extension under the provisions of the Paperwork Reduction Act of 1995. The...

A Comparative Analysis of the Snort and Suricata Intrusion-Detection Systems

DTIC Science & Technology

2011-09-01

Category: Test Rules Test #6: Simple LFI Attack 43 Snort True Positive: Snort generated an alert based on the ‘/etc/ passwd ’ string passed...through an HTTP command. Suricata True Positive: Suricata generated an alert based on the ‘/etc/ passwd ’ string passed through an HTTP command

32 CFR 644.547 - Extensions of time.

Code of Federal Regulations, 2010 CFR

2010-07-01

... ESTATE HANDBOOK Disposal Sale Procedure § 644.547 Extensions of time. Granting an extension of time... development and administration of sales programs will help to avoid unjustified requests for extensions of time: (a) Establishment of realistic periods for completion of the sales contract. (b) Necessary and...

32 CFR 644.547 - Extensions of time.

Code of Federal Regulations, 2011 CFR

2011-07-01

... ESTATE HANDBOOK Disposal Sale Procedure § 644.547 Extensions of time. Granting an extension of time... development and administration of sales programs will help to avoid unjustified requests for extensions of time: (a) Establishment of realistic periods for completion of the sales contract. (b) Necessary and...

75 FR 38091 - Agency Information Collection Extension

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-01

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75 FR 54859 - Agency Information Collection Extension

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-09

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76 FR 53887 - Agency Information Collection Extension

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-30

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76 FR 31598 - Agency Information Collection Extension

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-01

... DEPARTMENT OF ENERGY Agency Information Collection Extension AGENCY: U.S. Department of Energy... Department of Energy (DOE) has submitted an information collection request to the OMB for extension under the provisions of the Paperwork Reduction Act of 1995. The information collection requests a three-year extension...

The Intelligent System of Cardiovascular Disease Diagnosis Based on Extension Data Mining

NASA Astrophysics Data System (ADS)

Sun, Baiqing; Li, Yange; Zhang, Lin

This thesis gives the general definition of the concepts of extension knowledge, extension data mining and extension data mining theorem in high dimension space, and also builds the IDSS integrated system by the rough set, expert system and neural network, develops the relevant computer software. From the diagnosis tests, according to the common diseases of myocardial infarctions, angina pectoris and hypertension, and made the test result with physicians, the results shows that the sensitivity, specific and accuracy diagnosis by the IDSS are all higher than the physicians. It can improve the rate of the accuracy diagnosis of physician with the auxiliary help of this system, which have the obvious meaning in low the mortality, disability rate and high the survival rate, and has strong practical values and further social benefits.

Bacteriophage Amplification-Coupled Detection and Identification of Bacterial Pathogens

NASA Astrophysics Data System (ADS)

Cox, Christopher R.; Voorhees, Kent J.

Current methods of species-specific bacterial detection and identification are complex, time-consuming, and often require expensive specialized equipment and highly trained personnel. Numerous biochemical and genotypic identification methods have been applied to bacterial characterization, but all rely on tedious microbiological culturing practices and/or costly sequencing protocols which render them impractical for deployment as rapid, cost-effective point-of-care or field detection and identification methods. With a view towards addressing these shortcomings, we have exploited the evolutionarily conserved interactions between a bacteriophage (phage) and its bacterial host to develop species-specific detection methods. Phage amplification-coupled matrix assisted laser desorption time-of-flight mass spectrometry (MALDI-TOF-MS) was utilized to rapidly detect phage propagation resulting from species-specific in vitro bacterial infection. This novel signal amplification method allowed for bacterial detection and identification in as little as 2 h, and when combined with disulfide bond reduction methods developed in our laboratory to enhance MALDI-TOF-MS resolution, was observed to lower the limit of detection by several orders of magnitude over conventional spectroscopy and phage typing methods. Phage amplification has been combined with lateral flow immunochromatography (LFI) to develop rapid, easy-to-operate, portable, species-specific point-of-care (POC) detection devices. Prototype LFI detectors have been developed and characterized for Yersinia pestis and Bacillus anthracis, the etiologic agents of plague and anthrax, respectively. Comparable sensitivity and rapidity was observed when phage amplification was adapted to a species-specific handheld LFI detector, thus allowing for rapid, simple, POC bacterial detection and identification while eliminating the need for bacterial culturing or DNA isolation and amplification techniques.

Rural Extension Services. Policy Research Working Paper.

ERIC Educational Resources Information Center

Anderson, Jock R.; Feder, Gershon

This paper analyzes the considerations that lead policy makers to undertake extension investments as a key public responsibility, as well as the complex set of factors and intra-agency incentives that explain variations in performance between different extension systems. The goals of extension include transferring knowledge from researchers to…

49 CFR 22.61 - Loan guarantee extensions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 1 2010-10-01 2010-10-01 false Loan guarantee extensions. 22.61 Section 22.61 Transportation Office of the Secretary of Transportation SHORT-TERM LENDING PROGRAM (STLP) Loan Administration § 22.61 Loan guarantee extensions. An extension of the original loan guarantee may be requested, in...

Late Quaternary Arc-parallel Extension of the Kongur Extensional System (KES), Chinese Pamir

NASA Astrophysics Data System (ADS)

Chen, Jie; Schoenbohm, Lindsay M.; Yuan, Zhaode; Li, Wenqiao; Li, Tao; Owen, Lewis A.; Sobel, Edward R.; Hedrick, Kate

2015-04-01

Active deformation in the Chinese Pamir plateau is dominated by east-west extension along the active Kongur extensional system (KES). The KES lies along the northeastern margin of the Pamir at the western end of the Himalayan-Tibetan orogenic belt, and is part of a regional fault system which accommodates east-west extension in the hanging wall of the active Main Pamir Thrust (MPT). Previous work has shown that the MPT has been active since at least the Late Oligocene and accommodates northward motion of the Pamir salient over the Tarim and Tajik basins. It has been proposed that North-directed thrusting along the Main Pamir thrust has been interpreted to be related to east-west extension in the northern Pamir by either extensional collapse of over-thickened crust, or radial thrusting, or oroclinal bending along the Main Pamir Thrust. Alternatively, the east-west extension is related to northward propagation of the right-slip Karakoram fault. A newer model relates the extension to gravitational collapse of the Pamir into the Tadjik depression. Clearly the precise driver remains poorly understood. To better understand the nature of extension in the Pamir and to test the existing models, late Quaternary slip rate along the KES need to be defined using geomorphic mapping, geodetic surveying, Be-10 surface exposure and depth profile dating to quantify rates of fault slip using multiple landforms as strain markers such as offset outwash terraces, lateral moraines, and landslides at five sites, to identify spatial patterns in deformation rates. The preliminary results show that the overall extension direction is subhorizontal, is oriented E-W, and occurs at a high rate of about 7 mm/yr along the Muji and Qimugan faults to the north and deceased to about 1 mm/yr at Kuzigan to the south near Tashkurgan town, which matches the pattern of GPS data. A regional compilation from this study and existing data shows that recent extension along the KES is arc-parallel extension

47 CFR 27.1238 - Eligible costs.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES MISCELLANEOUS WIRELESS...) Legal fees; (5) Site acquisition fees-contractor; and (6) Arbitrator fee; (c) Transmission facility—analog conversion costs: (1) Transmitter upgrading or retuning; (2) Combiner re-tuning or new; (3) Power...

47 CFR 27.1238 - Eligible costs.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES MISCELLANEOUS WIRELESS...) Legal fees; (5) Site acquisition fees-contractor; and (6) Arbitrator fee; (c) Transmission facility... manage the BTA conversion); and (10) Travel and Per Diem Cost. (d) Transmission facility-digital...

47 CFR 27.1238 - Eligible costs.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES MISCELLANEOUS WIRELESS...) Legal fees; (5) Site acquisition fees-contractor; and (6) Arbitrator fee; (c) Transmission facility... manage the BTA conversion); and (10) Travel and Per Diem Cost. (d) Transmission facility-digital...

47 CFR 27.1238 - Eligible costs.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES MISCELLANEOUS WIRELESS...) Legal fees; (5) Site acquisition fees-contractor; and (6) Arbitrator fee; (c) Transmission facility... manage the BTA conversion); and (10) Travel and Per Diem Cost. (d) Transmission facility-digital...

47 CFR 27.1238 - Eligible costs.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES MISCELLANEOUS WIRELESS...) Legal fees; (5) Site acquisition fees-contractor; and (6) Arbitrator fee; (c) Transmission facility... manage the BTA conversion); and (10) Travel and Per Diem Cost. (d) Transmission facility-digital...

Purdue Extension: Employee Engagement and Leadership Style

ERIC Educational Resources Information Center

Abbott, Angela R.

2017-01-01

The purpose of this quantitative study was to assess the Purdue Extension county directors' level of engagement and leadership style and to examine the relationship between these two variables. The study aimed to inform a professional development training program for all Purdue Extension county extension directors. Survey data were collected from…

CR extension from hypersurfaces of higher type

NASA Astrophysics Data System (ADS)

Baracco, Luca

2007-07-01

We prove extension of CR functions from a hypersurface M of in presence of the so-called sector property. If M has finite type in the Bloom-Graham sense, then our result is already contained in [C. Rea, Prolongement holomorphe des fonctions CR, conditions suffisantes, C. R. Acad. Sci. Paris 297 (1983) 163-166] by Rea. We think however, that the argument of our proof carries an expressive geometric meaning and deserves interest on its own right. Also, our method applies in some case to hypersurfaces of infinite type; note that for these, the classical methods fail. CR extension is treated by many authors mainly in two frames: extension in directions of iterated of commutators of CR vector fields (cf., for instance, [A. Boggess, J. Pitts, CR extension near a point of higher type, Duke Math. J. 52 (1) (1985) 67-102; A. Boggess, J.C. Polking, Holomorphic extension of CR functions, Duke Math. J. 49 (1982) 757-784. ; M.S. Baouendi, L. Rothschild, Normal forms for generic manifolds and holomorphic extension of CR functions, J. Differential Geom. 25 (1987) 431-467. ]); extension through minimality towards unprecised directions [A.E. Tumanov, Extension of CR-functions into a wedge, Mat. Sb. 181 (7) (1990) 951-964. ; A.E. Tumanov, Analytic discs and the extendibility of CR functions, in: Integral Geometry, Radon Transforms and Complex Analysis, Venice, 1996, in: Lecture Notes in Math., vol. 1684, Springer, Berlin, 1998, pp. 123-141].

Signature extension: An approach to operational multispectral surveys

NASA Technical Reports Server (NTRS)

Nalepka, R. F.; Morgenstern, J. P.

1973-01-01

Two data processing techniques were suggested as applicable to the large area survey problem. One approach was to use unsupervised classification (clustering) techniques. Investigation of this method showed that since the method did nothing to reduce the signal variability, the use of this method would be very time consuming and possibly inaccurate as well. The conclusion is that unsupervised classification techniques of themselves are not a solution to the large area survey problem. The other method investigated was the use of signature extension techniques. Such techniques function by normalizing the data to some reference condition. Thus signatures from an isolated area could be used to process large quantities of data. In this manner, ground information requirements and computer training are minimized. Several signature extension techniques were tested. The best of these allowed signatures to be extended between data sets collected four days and 80 miles apart with an average accuracy of better than 90%.

A Comparison of Agricultural Extension in Five States.

ERIC Educational Resources Information Center

Rogers, Everett M.

The nature of the Cooperative Extension Service in agriculture was examined to identify aspects that could be applied to the design of an educational extension service. To learn about the organization, programs, and priorities of Cooperative Extension, employees of the state extension services in California, Colorado, New Mexico, New York, and…

Inelastic Scattering Of Electrons By Protons

DOE R&D Accomplishments Database

Cone, A. A.; Chen, K. W.; Dunning, J. R. Jr.; Hartwig, G.; Ramsey, N. F.; Walker, J. K.; Wilson, R.

1966-12-01

The inelastic scattering of electrons by protons has been measured at incident electron energies up to 5 BeV/c and momentum transfers q{sup 2}=4(BeV/c){sup 2}. Excitation of known nucleon resonances at M=1238, 1512, 1688 and possibly 1920 MeV have been observed. The calculations for the resonance at M=1238 MeV have been compared with calculations by Adler based on the dispersion theory of Chew, Goldberger, Low and Nambu. The agreement is good. Qualitative models are discussed for the other resonances.

Adaptation to walking with an exoskeleton that assists ankle extension.

PubMed

Galle, S; Malcolm, P; Derave, W; De Clercq, D

2013-07-01

The goal of this study was to investigate adaptation to walking with bilateral ankle-foot exoskeletons with kinematic control that assisted ankle extension during push-off. We hypothesized that subjects would show a neuromotor and metabolic adaptation during a 24min walking trial with a powered exoskeleton. Nine female subjects walked on a treadmill at 1.36±0.04ms(-1) during 24min with a powered exoskeleton and 4min with an unpowered exoskeleton. Subjects showed a metabolic adaptation after 18.5±5.0min, followed by an adapted period. Metabolic cost, electromyography and kinematics were compared between the unpowered condition, the beginning of the adaptation and the adapted period. In the beginning of the adaptation (4min), a reduction in metabolic cost of 9% was found compared to the unpowered condition. This reduction was accompanied by reduced muscular activity in the plantarflexor muscles, as the powered exoskeleton delivered part of the necessary ankle extension moment. During the adaptation this metabolic reduction further increased to 16%, notwithstanding a constant exoskeleton assistance. This increased reduction is the result of a neuromotor adaptation in which subjects adapt to walking with the exoskeleton, thereby reducing muscular activity in all leg muscles. Because of the fast adaptation and the significant reductions in metabolic cost we want to highlight the potential of an ankle-foot exoskeleton with kinematic control that assists ankle extension during push-off. Copyright © 2013 Elsevier B.V. All rights reserved.

7 CFR 15b.27 - Extension education.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 1 2011-01-01 2011-01-01 false Extension education. 15b.27 Section 15b.27 Agriculture... Education § 15b.27 Extension education. (a) General. A recipient to which this subpart applies that provides extension education may not, on the basis of handicap, exclude qualified handicapped persons. A recipient...

7 CFR 15b.27 - Extension education.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 1 2012-01-01 2012-01-01 false Extension education. 15b.27 Section 15b.27 Agriculture... Education § 15b.27 Extension education. (a) General. A recipient to which this subpart applies that provides extension education may not, on the basis of handicap, exclude qualified handicapped persons. A recipient...

7 CFR 15b.27 - Extension education.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 1 2014-01-01 2014-01-01 false Extension education. 15b.27 Section 15b.27 Agriculture... Education § 15b.27 Extension education. (a) General. A recipient to which this subpart applies that provides extension education may not, on the basis of handicap, exclude qualified handicapped persons. A recipient...

7 CFR 15b.27 - Extension education.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 1 2013-01-01 2013-01-01 false Extension education. 15b.27 Section 15b.27 Agriculture... Education § 15b.27 Extension education. (a) General. A recipient to which this subpart applies that provides extension education may not, on the basis of handicap, exclude qualified handicapped persons. A recipient...

43 CFR 3107.1 - Extension by drilling.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false Extension by drilling. 3107.1 Section 3107..., DEPARTMENT OF THE INTERIOR MINERALS MANAGEMENT (3000) OIL AND GAS LEASING Continuation, Extension or Renewal § 3107.1 Extension by drilling. Any lease on which actual drilling operations were commenced prior to the...

43 CFR 3107.1 - Extension by drilling.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false Extension by drilling. 3107.1 Section 3107..., DEPARTMENT OF THE INTERIOR MINERALS MANAGEMENT (3000) OIL AND GAS LEASING Continuation, Extension or Renewal § 3107.1 Extension by drilling. Any lease on which actual drilling operations were commenced prior to the...

43 CFR 3107.1 - Extension by drilling.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false Extension by drilling. 3107.1 Section 3107..., DEPARTMENT OF THE INTERIOR MINERALS MANAGEMENT (3000) OIL AND GAS LEASING Continuation, Extension or Renewal § 3107.1 Extension by drilling. Any lease on which actual drilling operations were commenced prior to the...

7 CFR 15b.27 - Extension education.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 1 2010-01-01 2010-01-01 false Extension education. 15b.27 Section 15b.27 Agriculture... Education § 15b.27 Extension education. (a) General. A recipient to which this subpart applies that provides extension education may not, on the basis of handicap, exclude qualified handicapped persons. A recipient...

Anticommutative extension of the Adler map

NASA Astrophysics Data System (ADS)

Konstantinou-Rizos, S.; Mikhailov, A. V.

2016-07-01

We construct a noncommutative (Grassmann) extension of the well-known Adler Yang-Baxter map. It satisfies the Yang-Baxter equation, it is reversible and birational. Our extension preserves all the properties of the original map except the involutivity.

Tennessee's Extension Food and Nutrition Education Program.

ERIC Educational Resources Information Center

Tennessee Univ., Knoxville. Agricultural Extension Service.

The Extension Food and Nutrition Education program was set up by the University of Tennessee Agricultural Extension Service to assist low-income families in improving their diets. Carrying out the program on a one-to-one basis are 365 assistants who are taught the basics of nutrition by trained home economics extension agents. These assistants…

49 CFR 190.319 - Petitions for extension of time to comment.

Code of Federal Regulations, 2010 CFR

2010-10-01

... the time for petitioner's comments. A petition is granted only if the petitioner shows good cause for... 49 Transportation 3 2010-10-01 2010-10-01 false Petitions for extension of time to comment. 190... AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE...

Scientific and Engineering Studies: Spectral Estimation

DTIC Science & Technology

1989-08-11

PROBLEM SOLUTION Four different constrained problems will be addressed in this section: con- strained window duration L ; constrained equivalent...sm(frtp + C, ^ smk ) » 0. (B_18) (B-19) The simultaneous solution of (B-ll) and (B-18), with smallest *< , is then given by q =.?0n l^fi

PKG-Mediated MAPK Signaling Is Necessary for Long-Term Operant Memory in "Aplysia"

ERIC Educational Resources Information Center

Michel, Maximilian; Green, Charity L.; Eskin, Arnold; Lyons, Lisa C.

2011-01-01

Signaling pathways necessary for memory formation, such as the mitogen-activated protein kinase (MAPK) pathway, appear highly conserved across species and paradigms. Learning that food is inedible (LFI) represents a robust form of associative, operant learning that induces short- (STM) and long-term memory (LTM) in "Aplysia." We investigated the…

Working with Our Publics. In-Service Education for Cooperative Extension. Module 2. The Extension Education Process.

ERIC Educational Resources Information Center

Mustian, R. David; And Others

This module is the second in an inservice education series for extension professionals that consists of seven independent training modules. It is an introduction to, and guided practice in, the premises, concepts, and processes of nonformal extension education--planning, designing and implementing, and evaluating and accounting for extension…

Influence of fracture extension on in-situ stress in tight reservoir

NASA Astrophysics Data System (ADS)

Zhang, Yongping; Wei, Xu; Zhang, Ye; Xing, Libo; Xu, Jianjun

2018-01-01

Currently, hydraulic fracturing is an important way to develop low permeability reservoirs. The fractures produced during the fracturing process are the main influencing factors of changing in-situ stress. In this paper, the influence of fracture extension on in-situ stress is studied by establishing a mathematical model to describe the relationship between fracture length and in-situ stress. The results show that the growth rate gradually decreases after the fracture reaches a certain length with the increase of fracturing time; the continuous extension of the fracture is the main factor to change the in-situ stress. In order to reduce the impact on the subsequent fracture extension due to the changing of in-situ stress, controlling fracturing time and fracture length without affecting the stimulated reservoir effect is an important way. The results presented in this study can effectively reduce the impact of changing of in-situ stress on subsequent fracturing construction.

Spinal Epidural Haemangioma Associated with Extensive Gastrointestinal Haemangiomas

PubMed Central

Cheng, L.T.E.; Lim, W.E.H.

2005-01-01

Summary A case of spinal epidural cavernous haemangioma associated with gastrointestinal haemangiomas is discussed. The patient was a young Chinese female presenting with chronic lower back pain. She had a history of extensive gastric and small bowel haemangiomas. Lumbar spine MRI showed a heterogeneously enhancing epidural mass infiltrating the paravertebral muscles. Open biopsy confirmed an epidural cavernous haemangioma. To our knowledge, an association between spinal epidural cavernous haemangiomas and gastrointestinal haemangiomas has not been reported. PMID:20584496

Forces directing germ-band extension in Drosophila embryos.

PubMed

Kong, Deqing; Wolf, Fred; Großhans, Jörg

2017-04-01

Body axis elongation by convergent extension is a conserved developmental process found in all metazoans. Drosophila embryonic germ-band extension is an important morphogenetic process during embryogenesis, by which the length of the germ-band is more than doubled along the anterior-posterior axis. This lengthening is achieved by typical convergent extension, i.e. narrowing the lateral epidermis along the dorsal-ventral axis and simultaneous extension along the anterior-posterior axis. Germ-band extension is largely driven by cell intercalation, whose directionality is determined by the planar polarity of the tissue and ultimately by the anterior-posterior patterning system. In addition, extrinsic tensile forces originating from the invaginating endoderm induce cell shape changes, which transiently contribute to germ-band extension. Here, we review recent progress in understanding of the role of mechanical forces in germ-band extension. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.

Professional Competencies Needed by Extension Agents in the Florida Cooperative Extension Service. A Report of Research.

ERIC Educational Resources Information Center

Beeman, Carl E.; And Others

A study was conducted to identify and verify the professional competencies needed by extension agents in Florida. Closed form opinionnaires were used to survey 254 extension agents and fifteen state staff members concerning 158 competencies. Among the findings was that state staff members rated all competency categories higher than did incumbent…

Influence of hamstring muscles extensibility on spinal curvatures and pelvic tilt in highly trained cyclists.

PubMed

Muyor, José M; Alacid, Fernando; López-Miñarro, Pedro A

2011-09-01

The purpose of this study was to determine the influence of hamstring muscles extensibility in standing, maximal trunk flexion with knees extended and on the bicycle in lower handlebar-hands position of highly trained cyclists. Ninety-six cyclists were recruited for the study (mean ± SD, age: 30.36 ± 5.98 years). Sagittal spinal curvatures and pelvic tilt were measured in the standing position, maximal trunk flexion with knees extended (sit-and-reach test) and while sitting on a bicycle in lower handlebar-hand position using a Spinal Mouse system. Hamstring muscles extensibility was determined in both legs by passive straight leg raise test (PSLR). The sample was divided into three groups according to PSLR angle: (1) reduced extensibility (PSLR < 80º; n = 30), (2) moderate hamstring extensibility group (PSLR = 80º - 90º; n = 35), and (3) high hamstring extensibility (PSLR = > 90º; n = 31). ANOVA analysis showed significant differences among groups for thoracic (p < 0.001) and pelvic tilt (p < 0.001) angles in the sit-and-reach test. No differences were found between groups for standing and on the bicycle position. Post hoc analysis showed significant differences in all pairwise comparisons for thoracic angle (p < 0.01) and pelvic angle (p < 0.001) in the sit-and-reach test. No differences were found in lumbar angle in any posture. In conclusion, the hamstring muscles extensibility influence the thoracic and pelvic postures when maximal trunk flexion with knees extended is performed, but not when cyclists are seated on their bicycles.

Influence of Hamstring Muscles Extensibility on Spinal Curvatures and Pelvic Tilt in Highly Trained Cyclists

PubMed Central

Muyor, José M.; Alacid, Fernando; López-Miñarro, Pedro A.

2011-01-01

The purpose of this study was to determine the influence of hamstring muscles extensibility in standing, maximal trunk flexion with knees extended and on the bicycle in lower handlebar-hands position of highly trained cyclists. Ninety-six cyclists were recruited for the study (mean ± SD, age: 30.36 ± 5.98 years). Sagittal spinal curvatures and pelvic tilt were measured in the standing position, maximal trunk flexion with knees extended (sit-and-reach test) and while sitting on a bicycle in lower handlebar-hand position using a Spinal Mouse system. Hamstring muscles extensibility was determined in both legs by passive straight leg raise test (PSLR). The sample was divided into three groups according to PSLR angle: (1) reduced extensibility (PSLR < 80º; n = 30), (2) moderate hamstring extensibility group (PSLR = 80º – 90º; n = 35), and (3) high hamstring extensibility (PSLR = > 90º; n = 31). ANOVA analysis showed significant differences among groups for thoracic (p < 0.001) and pelvic tilt (p < 0.001) angles in the sit-and-reach test. No differences were found between groups for standing and on the bicycle position. Post hoc analysis showed significant differences in all pairwise comparisons for thoracic angle (p < 0.01) and pelvic angle (p < 0.001) in the sit-and-reach test. No differences were found in lumbar angle in any posture. In conclusion, the hamstring muscles extensibility influence the thoracic and pelvic postures when maximal trunk flexion with knees extended is performed, but not when cyclists are seated on their bicycles PMID:23486997

Analysis of Three Sugarcane Homo/Homeologous Regions Suggests Independent Polyploidization Events of Saccharum officinarum and Saccharum spontaneum

PubMed Central

Vilela, Mariane de Mendonça; Del Bem, Luiz Eduardo; Van Sluys, Marie-Anne; de Setta, Nathalia; Kitajima, João Paulo; Cruz, Guilherme Marcelo Queiroga; Sforça, Danilo Augusto; de Souza, Anete Pereira; Ferreira, Paulo Cavalcanti Gomes; Grativol, Clícia; Cardoso-Silva, Claudio Benicio; Vicentini, Renato

2017-01-01

Whole genome duplication has played an important role in plant evolution and diversification. Sugarcane is an important crop with a complex hybrid polyploid genome, for which the process of adaptation to polyploidy is still poorly understood. In order to improve our knowledge about sugarcane genome evolution and the homo/homeologous gene expression balance, we sequenced and analyzed 27 BACs (Bacterial Artificial Chromosome) of sugarcane R570 cultivar, containing the putative single-copy genes LFY (seven haplotypes), PHYC (four haplotypes), and TOR (seven haplotypes). Comparative genomic approaches showed that these sugarcane loci presented a high degree of conservation of gene content and collinearity (synteny) with sorghum and rice orthologous regions, but were invaded by transposable elements (TE). All the homo/homeologous haplotypes of LFY, PHYC, and TOR are likely to be functional, because they are all under purifying selection (dN/dS ≪ 1). However, they were found to participate in a nonequivalently manner to the overall expression of the corresponding gene. SNPs, indels, and amino acid substitutions allowed inferring the S. officinarum or S. spontaneum origin of the TOR haplotypes, which further led to the estimation that these two sugarcane ancestral species diverged between 2.5 and 3.5 Ma. In addition, analysis of shared TE insertions in TOR haplotypes suggested that two autopolyploidization may have occurred in the lineage that gave rise to S. officinarum, after its divergence from S. spontaneum. PMID:28082603

Magnetic resonance imaging for simultaneous morphological and functional evaluation of esophageal motility disorders.

PubMed

Miyazaki, Yasuhiro; Nakajima, Kiyokazu; Sumikawa, Mitsuhiro; Yamasaki, Makoto; Takahashi, Tsuyoshi; Miyata, Hiroshi; Takiguchi, Shuji; Kurokawa, Yukinori; Tomiyama, Noriyuki; Mori, Masaki; Doki, Yuichiro

2014-04-01

The purpose of this study was to evaluate the feasibility and safety of esophageal functional magnetic resonance imaging (fMRI) for the diagnosis of achalasia. Eleven patients with suspected achalasia and three normal subjects underwent fMRI while swallowing clear liquid with original sequences; "T2-weighed single-shot fast spin-echo" and "Fast Imaging Employing Steady-state Acquisition". The fMRI-based diagnosis was compared with that based on manometry. The luminal fluctuation index (LFI) and Dd/Ds ratio were used for the objective evaluation of the esophageal peristalsis and relaxation of the lower esophageal sphincter (LES). Functional MRI showed a dilated tortuous esophagus with no tumor, poor clearance, simultaneous waves, aperistalsis, and impaired LES relaxation in all but one case, allowing the diagnosis of achalasia with accuracy similar to that of manometry. The LFI (median 0.08, range 0.03-0.25) and Dd/Ds ratio (1.40, 1.0-2.3) of the patient group were significantly lower than those of the normal subjects [1.50, 2.32-4.05, and 2.59 (2.32-4.05)]. No severe adverse events directly related to fMRI were noted. Using our protocol, fMRI was considered to be safe and feasible for the diagnosis of achalasia. Given the widespread use of MRI, esophageal fMRI, which does not require exposure to radiation, could be a potentially useful diagnostic tool for patients with esophageal motility disorders.

Dynamics of Lithospheric Extension and Residual Topography in Southern Tibet

NASA Astrophysics Data System (ADS)

Chen, B.; Shahnas, M. H.; Pysklywec, R.; Sengul Uluocak, E.

2017-12-01

Although the north-south (N-S) convergence between India and Eurasia is ongoing, a number of north-south trending rifts (e.g., Tangra Yum Co Rift, Yadong-Gulu Rift and Cona Rift) and normal faulting are observed at the surface of southern Tibet, suggesting an east-west (E-W) extension tectonic regime. The earthquake focal mechanisms also show that deformation of southern Tibet is dominated by E-W extension across these N-S trending rifts. Because the structure of the lithosphere and underlying mantle is poorly understood, the origin of the east-west extension of southern Tibet is still under debate. Gravitational collapse, oblique convergence, and mantle upwelling are among possible responsible mechanisms. We employ a 3D-spherical control volume model of the present-day mantle flow to understand the relationship between topographic features (e.g., rifts and the west-east extension), intermediate-depth earthquakes, and tectonic stresses induced by mantle flow beneath the region. The thermal structure of the mantle and crust is obtained from P and S-wave seismic inversions and heat flow data. Power-law creep with viscous-plastic rheology, describing the behavior of the lithosphere and mantle material is employed. We determine the models which can best reconcile the observed features of southern Tibet including surface heat flow, residual topography with uplift and subsidence, reported GPS rates of the vertical movements, and the earthquake events. The 3D geodynamic modeling of the contemporary mantle flow-lithospheric response quantifies the relative importance of the various proposed mechanism responsible for the E-W extension and deep earthquakes in southern Tibet. The results also have further implications for the magmatic activities and crustal rheology of the region.

Extensions of the standard model

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ramond, P.

1983-01-01

In these lectures we focus on several issues that arise in theoretical extensions of the standard model. First we describe the kinds of fermions that can be added to the standard model without affecting known phenomenology. We focus in particular on three types: the vector-like completion of the existing fermions as would be predicted by a Kaluza-Klein type theory, which we find cannot be realistically achieved without some chiral symmetry; fermions which are vector-like by themselves, such as do appear in supersymmetric extensions, and finally anomaly-free chiral sets of fermions. We note that a chiral symmetry, such as the Peccei-Quinnmore » symmetry can be used to produce a vector-like theory which, at scales less than M/sub W/, appears to be chiral. Next, we turn to the analysis of the second hierarchy problem which arises in Grand Unified extensions of the standard model, and plays a crucial role in proton decay of supersymmetric extensions. We review the known mechanisms for avoiding this problem and present a new one which seems to lead to the (family) triplication of the gauge group. Finally, this being a summer school, we present a list of homework problems. 44 references.« less

A Case of Uveal Colobomas Showing Marked Left-Right Difference in Diabetic Retinopathy.

PubMed

Moriya, Takeshi; Ochi, Ryosuke; Imagawa, Yukihiro; Sato, Bumpei; Morishita, Seita; Tonari, Masahiro; Fukumoto, Masanori; Suzuki, Hiroyuki; Kobayashi, Takatoshi; Kida, Teruyo; Ikeda, Tsunehiko

2016-01-01

Congenital uveal colobomas, including inferior iris and choroidal colobomas, are associated with microcornea and microphthalmia and often show left-right differences (laterality). The purpose of this study was to report a case of choroidal coloboma associated with left-right differences in diabetic retinopathy (DR). This study reports a 59-year-old male with bilateral iris and choroidal colobomas. The colobomatous area in the patient's right eye extended to the macula, and his right eye had been amblyopic since birth. The colobomatous area in his left eye was less extensive and did not involve the macula. Examination of the patient's left eye revealed multiple hemorrhages and hard exudates in the macula due to DR, but examination of his right eye showed almost no changes in DR, thus revealing a marked left-right difference. Optical coherence tomography showed more extensive retinal thinning in the patient's right eye than in his left eye. Fluorescein fundus angiography revealed a retinal nonperfusion area only in the left eye, and panretinal photocoagulation was subsequently performed. Our findings show that the reason for the left-right difference in DR was attributed to the more severe choroidal coloboma and retinal thinning in the patient's right eye compared to his left eye, thus reducing oxygen demand, as is also seen in eyes with severe myopia.

Using a Blog to Facilitate Extensive Reading: An Exploratory Study

ERIC Educational Resources Information Center

Chew, Magdalene Meow Khee; Lee, Catherine Cheng Kiat

2013-01-01

Research shows that extensive reading (ER) has many benefits for language acquisition. The challenge today is making ER appealing to the digital generation. For a possible solution, it is pertinent to look to the social media embraced by today's youths. This study was conducted to explore the use of the blog as a space for sharing peer-selected…

78 FR 15034 - Information Collection Extension

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-08

... DEPARTMENT OF THE INTERIOR U.S. Geological Survey [GX12GH009980000] Information Collection Extension AGENCY: U.S. Geological Survey, Interior. ACTION: Notice of an extension of an information... Budget (OMB) to approve the information collection (IC) described below. To comply with the Paperwork...

Mid-Career Extension Graduates' Perceptions of the Impact of a Demand-Driven, Extension Curriculum in Ghana

ERIC Educational Resources Information Center

Kwarteng, Joseph A.; Boateng, Samuel Akuamoah

2012-01-01

One of the major challenges facing Africa today is ensuring that extension practitioners are well trained to enable them function effectively as facilitators of change at the farmers' level. The purpose of this study was to examine the effectiveness of a mid-career B. Sc. Agricultural Extension Curriculum in meeting the educational needs of…

Theme--Teaming Up: Agricultural Education and Cooperative Extension.

ERIC Educational Resources Information Center

Gamon, Julia A.; And Others

1994-01-01

Includes "Similarities and Differences" (Gamon); "Preparing Agriculture Teachers and Extension Agents" (Seevers); "Teaching and Extension" (Graham); "Cooperation between 4-H and FFA" (Hink); "Team Approach to Agricultural and Extension Education in Georgia" (Iverson, Rohs); "Agricultural…

U.S. EPA, Pesticide Product Label, FARMCRAFT TOXAPHENE-10, 06/29/1973

EPA Pesticide Factsheets

2011-04-14

... lI lfi;"r J\\IlOrll(,\\'" f,'t'" "II'\\lt'r " ," ,\\ ho':t, .Ir uart frllul l'fHf'lJ('t'. bv fh,' IIt1r'lta~1 r fll bi~ tra()~(l'rf'l' l\\I't if I .. trll't ;lcl'(Irchp'I'" with .)irf'('lipf~ ai .. fin hflrewilh, ...

Middle Immersion Study 1988. Research Paper 88-08.

ERIC Educational Resources Information Center

Parkin, Michael; And Others

Ottawa's program of middle French immersion (MFI) instruction, beginning in fourth grade, was evaluated when the first cohort reached sixth grade. Results of the study were compared with those of other groups, particularly the early French immersion (EFI) program and late French immersion (LFI) program students. The evaluation also added data from…

Small Businessmen's Perceptions of University Extension.

ERIC Educational Resources Information Center

Douglah, Mohammad A.; Dopp, Arvid D.

A survey was made in Clark County, Wisconsin, of small businessmen's knowledge and perception of university extension. The businessmen appeared most knowledgeable about Extension programs offered through mass media, but less knowledgeable about local staff affiliation and relationship to the University of Wisconsin. They participated in Extension…

10 CFR 903.23 - Rate extensions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Rate extensions. 903.23 Section 903.23 Energy DEPARTMENT OF ENERGY POWER AND TRANSMISSION RATES Procedures for Public Participation in Power and Transmission Rate Adjustments and Extensions for the Alaska, Southeastern, Southwestern, and Western Area Power...

10 CFR 903.23 - Rate extensions.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Rate extensions. 903.23 Section 903.23 Energy DEPARTMENT OF ENERGY POWER AND TRANSMISSION RATES Procedures for Public Participation in Power and Transmission Rate Adjustments and Extensions for the Alaska, Southeastern, Southwestern, and Western Area Power...

10 CFR 903.23 - Rate extensions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Rate extensions. 903.23 Section 903.23 Energy DEPARTMENT OF ENERGY POWER AND TRANSMISSION RATES Procedures for Public Participation in Power and Transmission Rate Adjustments and Extensions for the Alaska, Southeastern, Southwestern, and Western Area Power...

10 CFR 903.23 - Rate extensions.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false Rate extensions. 903.23 Section 903.23 Energy DEPARTMENT OF ENERGY POWER AND TRANSMISSION RATES Procedures for Public Participation in Power and Transmission Rate Adjustments and Extensions for the Alaska, Southeastern, Southwestern, and Western Area Power...

Communication for extension: developing country experience.

PubMed

Meyer, A J

1985-01-01

This paper characterizes several major approaches to the use of communication in support of agricultural extension and suggests directions for change. The approaches discussed include: direct farmer contact, farmer forums, open broadcasting, advertising and social marketing, print media, multiple channel systems (campaigns and distance teaching), and comprehensive communication systems. Although all programs should be able to use media in interaction with training and the coordination of other inputs, this approach has not been comprehensively implemented in extension programs. There are few examples of cases where multiple methods have been brought together under a comprehensive communications strategy and institutionalized as part of an ongoing extension system. Lessons from social marketing in other sectors have not been exploited, while lessons from distance teaching have been underutilized. In addition, the networking and feedback functions of communication in extenson have not been given adequate attention. There is substantial potential for increasing the coverage and impact of agricultural extension through the more systematic and comprehensive use of communication.

Extension Learners' Use of Electronic Technology

ERIC Educational Resources Information Center

Guenthner, Joseph F.; Swan, Benjamin G.

2011-01-01

Extension clientele use electronic technology for entertainment, communication, and business. Educational programs that use electronic technology can enhance learning. To learn more about use of electronic technology among Extension clientele, we surveyed 80 university students and 135 potato farmers. We found that the farmers were likely to use…

Bibliography of U.S. Extension and Extension-related Publications on Nematodes

PubMed Central

1988-01-01

A listing was compiled of hematology publications available through the Cooperative Extension Service and similar organizations in the United States. It provides a convenient reference to current articles addressing many of the more applied aspects of plant nematology and nematode management. PMID:19290318

Capillary-tube-based extension of thermoacoustic theory for a random medium

NASA Astrophysics Data System (ADS)

Roh, Heui-Seol; Raspet, Richard; Bass, Henry E.

2005-09-01

Thermoacoustic theory for a single capillary tube is extended to random bulk medium on the basis of capillary tubes. The characteristics of the porous stack inside the resonator such as the tortuosity, dynamic shape factor, and porosity are introduced for the extension of wave equation by following Attenborough's approach. Separation of the dynamic shape factor for the viscous and thermal effect is adopted and scaling using the dynamic shape factor and tortuosity factor is demonstrated. The theoretical and experimental comparison of thermoviscous functions in reticulated vitreous carbon (RVC) and aluminum foam shows reasonable agreement. The extension is useful for investigations of the properties of a stack with arbitrary shapes of non-parallel pores.

FRET detection of lymphocyte function–associated antigen-1 conformational extension

PubMed Central

Chigaev, Alexandre; Smagley, Yelena; Haynes, Mark K.; Ursu, Oleg; Bologa, Cristian G.; Halip, Liliana; Oprea, Tudor; Waller, Anna; Carter, Mark B.; Zhang, Yinan; Wang, Wei; Buranda, Tione; Sklar, Larry A.

2015-01-01

Lymphocyte function–associated antigen 1 (LFA-1, CD11a/CD18, αLβ2-integrin) and its ligands are essential for adhesion between T-cells and antigen-presenting cells, formation of the immunological synapse, and other immune cell interactions. LFA-1 function is regulated through conformational changes that include the modulation of ligand binding affinity and molecular extension. However, the relationship between molecular conformation and function is unclear. Here fluorescence resonance energy transfer (FRET) with new LFA-1–specific fluorescent probes showed that triggering of the pathway used for T-cell activation induced rapid unquenching of the FRET signal consistent with extension of the molecule. Analysis of the FRET quenching at rest revealed an unexpected result that can be interpreted as a previously unknown LFA-1 conformation. PMID:25378583

Limited distal organelles and synaptic function in extensive monoaminergic innervation.

PubMed

Tao, Juan; Bulgari, Dinara; Deitcher, David L; Levitan, Edwin S

2017-08-01

Organelles such as neuropeptide-containing dense-core vesicles (DCVs) and mitochondria travel down axons to supply synaptic boutons. DCV distribution among en passant boutons in small axonal arbors is mediated by circulation with bidirectional capture. However, it is not known how organelles are distributed in extensive arbors associated with mammalian dopamine neuron vulnerability, and with volume transmission and neuromodulation by monoamines and neuropeptides. Therefore, we studied presynaptic organelle distribution in Drosophila octopamine neurons that innervate ∼20 muscles with ∼1500 boutons. Unlike in smaller arbors, distal boutons in these arbors contain fewer DCVs and mitochondria, although active zones are present. Absence of vesicle circulation is evident by proximal nascent DCV delivery, limited impact of retrograde transport and older distal DCVs. Traffic studies show that DCV axonal transport and synaptic capture are not scaled for extensive innervation, thus limiting distal delivery. Activity-induced synaptic endocytosis and synaptic neuropeptide release are also reduced distally. We propose that limits in organelle transport and synaptic capture compromise distal synapse maintenance and function in extensive axonal arbors, thereby affecting development, plasticity and vulnerability to neurodegenerative disease. © 2017. Published by The Company of Biologists Ltd.

10 CFR 905.33 - Extension formula.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Extension formula. 905.33 Section 905.33 Energy DEPARTMENT OF ENERGY ENERGY PLANNING AND MANAGEMENT PROGRAM Power Marketing Initiative § 905.33 Extension formula. (a) The amount of power to be extended to an existing customer shall be determined according to...

Community Leadership Development: Implications for Extension.

ERIC Educational Resources Information Center

Northeast Regional Center for Rural Development, University Park, PA.

Designed for extension personnel who are involved in community leadership (CL) programs, this publication summarizes recent national efforts that could be useful in developing and conducting CL programs, and current leadership theory and literature. Part 1 reports the results of the national survey, initiated in April 1985, of extension staff…

Extension, sedimentation and diapirism: understanding evolution of diapiric structures in the Central High Atlas using analogue modelling

NASA Astrophysics Data System (ADS)

Moragas, Mar; Vergés, Jaume; Nalpas, Thierry; Saura, Eduard; Diego Martín-Martín, Juan; Messager, Grégoire; Hunt, David William

2017-04-01

Analogue modelling has proven to be an essential tool for the study and analysis of the mechanisms involved in tectonic processes. Applied to salt tectonics, analogue modelling has been used to understand the mechanisms that trigger the onset of diapirs and the evolution of diapiric structures and minibasins. Analogue modelling has also been applied to analyse the impact of the progradation of sedimentary systems above a ductile layer, representing the source of diapirs. However, these models did not consider ongoing tectonic processes during progradation. To analyse how extension and sedimentary progradation influence on the formation of diapiric structures and their geometries, we present models composed of a mildly extension followed by post-extension period. Each model includes a particular sedimentary pattern: homogeneous sedimentation during extension and post-extension, homogeneous sedimentation during extension followed by prograding sedimentation during post-extension and prograding sedimentation during both extension and post-extension. Proximal high sedimentation rates enhance the mobilization of ductile material towards growing diapirs, resulting well-developed passive diapirs. Diapirs from distal domain of the model with post-extension progradation show silicone extrusions, that are caused by the decreased sedimentation rate associated to the progradation. By contrast, reduced sedimentation in the distal part of the model with syn- and post-extension progradation (3.5 times smaller than in the proximal domain) causes a limited migration of the silicone and hampers the transition from reactive diapirs to active and passive diapirs. These models show that the ratio between diapir growth and sedimentation rate, the time of the onset of the progradation and the relative thickness of the sedimentary cover beneath the prograding system have a clear impact on the final diapiric geometries. Additionally, we present two models with increasing amounts of

A Proposal for Public and Private Partnership in Extension.

PubMed

Krell, Rayda K; Fisher, Marc L; Steffey, Kevin L

2016-01-01

Public funding for Extension in the United States has been decreasing for many years, but farmers' need for robust information on which to make management decisions has not diminished. The current Extension funding challenges provide motivation to explore a different model for developing and delivering extension. The private sector has partnered with the public sector to fund and conduct agricultural research, but partnering on extension delivery has occurred far less frequently. The fundamental academic strength and established Extension network of the public sector combined with the ability of the private sector to encourage and deliver practical, implementable solutions has the potential to provide measurable benefits to farmers. This paper describes the current Extension climate, presents data from a survey about Extension and industry relationships, presents case studies of successful public- and private-sector extension partnerships, and proposes a framework for evaluating the state of effective partnerships. Synergistic public-private extension efforts could ensure that farmers receive the most current and balanced information available to help with their management decisions.

A Proposal for Public and Private Partnership in Extension

PubMed Central

Krell, Rayda K.; Fisher, Marc L.; Steffey, Kevin L.

2016-01-01

Public funding for Extension in the United States has been decreasing for many years, but farmers’ need for robust information on which to make management decisions has not diminished. The current Extension funding challenges provide motivation to explore a different model for developing and delivering extension. The private sector has partnered with the public sector to fund and conduct agricultural research, but partnering on extension delivery has occurred far less frequently. The fundamental academic strength and established Extension network of the public sector combined with the ability of the private sector to encourage and deliver practical, implementable solutions has the potential to provide measurable benefits to farmers. This paper describes the current Extension climate, presents data from a survey about Extension and industry relationships, presents case studies of successful public- and private-sector extension partnerships, and proposes a framework for evaluating the state of effective partnerships. Synergistic public–private extension efforts could ensure that farmers receive the most current and balanced information available to help with their management decisions. PMID:26949567

Topology Design for Directional Range Extension Networks with Antenna Blockage

DTIC Science & Technology

2017-03-19

introduced by pod-based antenna blockages. Using certain modeling approximations, the paper presents a quantitative analysis showing design trade-offs...parameters. Sec- tion IV develops quantitative relationships among key design elements and performance metrics. Section V considers some implications of the...Topology Design for Directional Range Extension Networks with Antenna Blockage Thomas Shake MIT Lincoln Laboratory shake@ll.mit.edu Abstract

Creating Teams Increases Extension Educator Productivity

ERIC Educational Resources Information Center

Chalker-Scott, Linda; Daniels, Catherine H.; Martini, Nicole

2016-01-01

The Garden Team at Washington State University is a transdisciplinary group of faculty, staff, and students with expertise in applied plant and soil sciences and an interest in Extension education. The team's primary mission is to create current, relevant, and peer-reviewed materials as Extension publications for home gardeners. The average yearly…

A New Funding Model for Extension

ERIC Educational Resources Information Center

Brown, Paul W.; Otto, Daniel M.; Ouart, Michael D.

2006-01-01

The traditional funding model of the Cooperative Extension System has been stretched to its limits by increasing demand for information and programs without concurrent increases in funding by the public sector. As the social, economic, and political environments have evolved and become more complex, extension is often asked to apply the expertise…

Influence of lumbar spine extension on vertical jump height during maximal squat jumping.

PubMed

Blache, Yoann; Monteil, Karine

2014-01-01

The purpose of this study was to determine the influence of lumbar spine extension and erector spinae muscle activation on vertical jump height during maximal squat jumping. Eight male athletes performed maximal squat jumps. Electromyograms of the erector spinae were recorded during these jumps. A simulation model of the musculoskeletal system was used to simulate maximal squat jumping with and without spine extension. The effect on vertical jump height of changing erector spinae strength was also tested through the simulated jumps. Concerning the participant jumps, the kinematics indicated a spine extension and erector spinae activation. Concerning the simulated jumps, vertical jump height was about 5.4 cm lower during squat jump without trunk extension compared to squat jump. These results were explained by greater total muscle work during squat jump, more especially by the erector spinae work (+119.5 J). The erector spinae may contribute to spine extension during maximal squat jumping. The simulated jumps confirmed this hypothesis showing that vertical jumping was decreased if this muscle was not taken into consideration in the model. Therefore it is concluded that the erector spinae should be considered as a trunk extensor, which enables to enhance total muscle work and consequently vertical jump height.

Non-Gaussian Distribution of DNA Barcode Extension In Nanochannels Using High-throughput Imaging

NASA Astrophysics Data System (ADS)

Sheats, Julian; Reinhart, Wesley; Reifenberger, Jeff; Gupta, Damini; Muralidhar, Abhiram; Cao, Han; Dorfman, Kevin

2015-03-01

We present experimental data for the extension of internal segments of highly confined DNA using a high-­throughput experimental setup. Barcode­-labeled E. coli genomic DNA molecules were imaged at a high areal density in square nanochannels with sizes ranging from 40 nm to 51 nm in width. Over 25,000 molecules were used to obtain more than 1,000,000 measurements for genomic distances between 2,500 bp and 100,000 bp. The distribution of extensions has positive excess kurtosis and is skew­ left due to weak backfolding in the channel. As a result, the two Odijk theories for the chain extension and variance bracket the experimental data. We compared to predictions of a harmonic approximation for the confinement free energy and show that it produces a substantial error in the variance. These results suggest an inherent error associated with any statistical analysis of barcoded DNA that relies on harmonic models for chain extension. Present address: Department of Chemical and Biological Engineering, Princeton University.

Extensive retroviral diversity in shark.

PubMed

Han, Guan-Zhu

2015-04-28

Retroviruses infect a wide range of vertebrates. However, little is known about the diversity of retroviruses in basal vertebrates. Endogenous retrovirus (ERV) provides a valuable resource to study the ecology and evolution of retrovirus. I performed a genome-scale screening for ERVs in the elephant shark (Callorhinchus milii) and identified three complete or nearly complete ERVs and many short ERV fragments. I designate these retroviral elements "C. milli ERVs" (CmiERVs). Phylogenetic analysis shows that the CmiERVs form three distinct lineages. The genome invasions by these retroviruses are estimated to take place more than 50 million years ago. My results reveal the extensive retroviral diversity in the elephant shark. Diverse retroviruses appear to have been associated with cartilaginous fishes for millions of years. These findings have important implications in understanding the diversity and evolution of retroviruses.

Investigation of an MSIS00 Density Modeling Discrepancy

DTIC Science & Technology

2015-04-20

07337 Taifun-1/ Cosmos 660 405 83 0.0053 08744 Taifun-1/ Cosmos 807 405 83 0.0053 12138 Taifun-1/ Cosmos 1238 415 83 0.0053 12388 Taifun-1/ Cosmos 1263 385...83 0.0053 14483 Taifun-1/ Cosmos 1508 390 83 0.0053 3.2 Results of ADOBE Area-to-mass Estimation ADOBE was run using the spheres listed in Table 2 for...0.1010 07337 Taifun-1/ Cosmos 660 405 0.0051 0.0053 08744 Taifun-1/ Cosmos 807 405 0.0055 0.0053 12138 Taifun-1/ Cosmos 1238 415 0.0053 0.0053 12388

Slow NE-SW to NNE-SSW extension in the Pasto Ventura region of the southern Puna Plateau

NASA Astrophysics Data System (ADS)

Zhou, R.; Schoenbohm, L. M.; Cosca, M. A.

2011-12-01

Recent extension on the Puna Plateau of NW Argentina has been linked to lithospheric foundering, gravitational spreading, and edge effects. However, the timing, kinematics and rate of extension are poorly constrained. In the Pasto Ventura region, along the southern margin of the plateau, we map out two different groups of faults: (1) recently formed Quaternary normal faults and strike-slip faults; and (2) pre-Quaternary reverse faults reactivated in the Quaternary. The faults in Group (1) are relatively short (~1-2 km) normal and strike-slip faults that offset Quaternary geomorphic features. The orientation of these faults indicates NE-SW to NNE-SSW extension. The faults in Group (2) bound exposures of basement rock and are associated with basaltic cinder cones and lava flows. Previous studies indicate they were reverse faults which have been reactivated as normal faults. We applied kinematic GPS surveying and 40Ar/39Ar dating of three cinder cones displaced by two of Group-(2) faults. Kinematic analysis on vertical and horizontal offsets obtained by GPS survey shows that the one fault is now undergoing NE-SW to NNE-SSW extension, consistent with Group (1) fault kinematics. A cinder cone has been displaced 34-40 meters horizontally along this fault, yielding a slow extension rate of 0.02-0.04 mm/yr since 0.8-0.5 Ma. The shift from contraction to extension in the Pasto Ventura region is estimated to be between 7.8 and 0.5 Ma, but more likely between 7.8 and 4 Ma. A regional compilation of kinematics on the southern plateau from this study and existing data, although sparse, shows two spatial groups: the extension directions are N-S to NE-SW south of 26°S latitude, while they are NW-SE to NNW-SSW north of 26°S latitude. Mafic volcanism, thought to indicate the timing of the onset of extension in the Puna, shows a similar pattern, with the oldest ages (up to 7.3 Ma) clustered near 26°S latitude, becoming younger to both the north and the south. Kinematic and

Planck focal plane instruments: advanced modelization and combined analysis

NASA Astrophysics Data System (ADS)

Zonca, Andrea; Mennella, Aniello

2012-08-01

This thesis is the result of my work as research fellow at IASF-MI, Milan section of the Istituto di Astrofisica Spaziale e Fisica Cosmica, part of INAF, Istituto Nazionale di Astrofisica. This work started in January 2006 in the context of the PhD school program in Astrophysics held at the Physics Department of Universita' degli Studi di Milano under the supervision of Aniello Mennella. The main topic of my work is the software modelling of the Low Frequency Instrument (LFI) radiometers. The LFI is one of the two instruments on-board the European Space Agency Planck Mission for high precision measurements of the anisotropies of the Cosmic Microwave Background (CMB). I was also selected to participate at the International Doctorate in Antiparticles Physics, IDAPP. IDAPP is funded by the Italian Ministry of University and Research (MIUR) and coordinated by Giovanni Fiorentini (Universita' di Ferrara) with the objective of supporting the growing collaboration between the Astrophysics and Particles Physics communities. It is an international program in collaboration with the Paris PhD school, involving Paris VI, VII and XI Universities, leading to a double French-Italian doctoral degree title. My work was performed with the co-tutoring of Jean-Michel Lamarre, Instrument Scientist of the High Frequency Instrument (HFI), the bolometric instrument on-board Planck. Thanks to this collaboration I had the opportunity to work with the HFI team for four months at the Paris Observatory, so that the focus of my activity was broadened and included the study of cross-correlation between HFI and LFI data. Planck is the first CMB mission to have on-board the same satellite very different detection technologies, which is a key element for controlling systematic effects and improve measurements quality.

Sensitivity of mechanical and metabolic functions to changes in coronary perfusion: A metabolic basis of perfusion-contraction coupling.

PubMed

Askenasy, N

2000-05-01

Experimental evidence indicates a metabolic basis of contraction-perfusion coupling during an increase in cardiac work load. This study aims to characterize adjustment of myocardial energy metabolism in response to acute low flow ischemia (LFI), and to determine its involvement in perfusion-contraction coupling. Intracellular parameters were measured in isolated rat hearts by NMR spectroscopy and biochemical methods during 30 min of graded LFI and reperfusion as compared to continuous perfusion (control). Oxygen pressure was set to reach maximal oxygen extraction at 70% coronary flow rate (CFR), therefore oxygen limitation was proportional to coronary underperfusion. At 69, 38 and 10% CFR left ventricular pressures decreased to 71, 43 and 25% of pre-ischemic values respectively (P<0.005 v 97% in control) without an increase in diastolic tone, and recovered to 92+/-3% after 30 min of reperfusion. Despite hydrolysis of high energy phosphates and cellular acidification, ADP concentrations were stable in underperfused hearts. At 69, 38 and 10% CFR, cytosolic phosphorylation potentials (PP) decreased from 74+/-10 m M(-1)during pre-ischemia to 40+/-6, 25+/-4 and 14+/-4 m M(-1)respectively (P<0.05 v 63+/-9 m M(-1)in control), and lactate efflux increased to 256+/-18, 386+/-22 and 490+/-43 micromol /gdw respectively (P<0.005 v 186+/-22 micromol/gdw in control). Glycogen contents decreased (P<0.005 v control) and accounted for 27-30% of lactate efflux. These results indicate: (a) proportionate depression of contraction force and glycogen contents, and increased glucose uptake and anaerobic energy production in the underperfused myocardium. Coordinated modulation of these parameters attributes cytosolic PP a regulatory function; (b) resetting of cytosolic PP to lower levels mediates perfusion-contraction coupling during graded LFI. The data are consistent with the concept that glycolytic energy production improves myocardial tolerance to ischemia. Copyright 2000 Academic

A Comparison of the Views of Extension Agents and Farmers regarding Extension Education Courses in Dezful, Iran

ERIC Educational Resources Information Center

Zare, Mohsen Nazarzadeh; Dorrani, Kamal; Lavasani, Masoud Gholamali

2012-01-01

Background and purpose: This study examines the views of farmers and extension agents participating in extension education courses in Dezful, Iran, with regard to problems with these courses. It relies upon a descriptive methodology, using a survey as its instrument. Sample: The statistical population consisted of 5060 farmers and 50 extension…

Interaction between mantle and crustal detachments: A nonlinear system controlling lithospheric extension

NASA Astrophysics Data System (ADS)

Rosenbaum, Gideon; Regenauer-Lieb, Klaus; Weinberg, Roberto F.

2010-11-01

We use numerical modeling to investigate the development of crustal and mantle detachments during lithospheric extension. Our models simulate a wide range of extensional systems with varying values of crustal thickness and heat flow, showing how strain localization in the mantle interacts with localization in the upper crust and controls the evolution of extensional systems. Model results reveal a richness of structures and deformation styles as a response to a self-organized mechanism that minimizes the internal stored energy of the system by localizing deformation. Crustal detachments, here referred as low-angle normal decoupling horizons, are well developed during extension of overthickened (60 km) continental crust, even when the initial heat flow is relatively low (50 mW m-2). In contrast, localized mantle deformation is most pronounced when the extended lithosphere has a normal crustal thickness (30-40 km) and an intermediate heat flow (60-70 mW m-2). Results show a nonlinear response to subtle changes in crustal thickness or heat flow, characterized by abrupt and sometimes unexpected switches in extension modes (e.g., from diffuse extensional deformation to effective lithospheric-scale rupturing) or from mantle- to crust-dominated strain localization. We interpret this nonlinearity to result from the interference of doming wavelengths in the presence of multiple necking instabilities. Disharmonic crust and mantle doming wavelengths results in efficient communication between shear zones at different lithospheric levels, leading to rupturing of the whole lithosphere. In contrast, harmonic crust and mantle doming inhibits interaction of shear zones across the lithosphere and results in a prolonged history of extension prior to continental breakup.

Extensive Mobile Thrombus of the Internal Carotid Discovered After Intravenous Thrombolysis

PubMed Central

Fugate, Jennifer E.; Hocker, Sara E.

2016-01-01

This case report describes a rare presentation of ischemic stroke secondary to an extensive internal carotid artery thrombus, subsequent therapeutic dilemma, and clinical management. A 58-year-old man was administered intravenous (IV) thrombolysis for right middle cerebral artery territory ischemic stroke symptoms. A computed tomography angiogram of the head and neck following thrombolysis showed a longitudinally extensive internal carotid artery thrombus originating at the region of high-grade calcific stenosis. Mechanical embolectomy was deferred because of risk of clot dislodgement and mild neurological symptoms. Recumbency and hemodynamic augmentation were used acutely to support cerebral perfusion. Anticoagulation was started 24 hours after thrombolysis. Carotid endarterectomy was completed successfully within 1 week of presentation. Clinical outcome was satisfactory with discharge modified Rankin Scale score 0. A longitudinally extensive carotid artery thrombus poses a risk of dislodgement and hemispheric stroke. Optimal management in these cases is not known with certainty. In our case, IV thrombolysis, hemodynamic augmentation, delayed anticoagulation, and carotid endarterectomy resulted in a favorable clinical outcome. PMID:28400904

36 CFR 251.89 - Time extensions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 36 Parks, Forests, and Public Property 2 2012-07-01 2012-07-01 false Time extensions. 251.89... Appeal of Decisions Relating to Occupancy and Use of National Forest System Lands § 251.89 Time extensions. (a) Filing of notice of appeal. Time for filing a notice of appeal is not extendable. (b) All...

39 CFR 963.10 - Continuances and extensions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... VIOLATIONS OF THE PANDERING ADVERTISEMENTS STATUTE, 39 U.S.C. 3008 § 963.10 Continuances and extensions. Continuances and extensions will be granted by the presiding officer for good cause shown. ...

Implicit personality theory in evaluation of brand extensions.

PubMed

Flaherty, K E; Pappas, J M

2000-06-01

Transference, the extent to which consumers transfer their opinions of a parent brand to a new extension, is critical to the success of any brand-extension strategy. Past research has shown that transference is a complex process that varies among persons depending upon an implicit personality theory, entity versus incremental. In a laboratory experiment analysis of ratings for 100 21-yr.-old undergraduates of attitude, perceived fit and risk, prior product involvement, and implicit personality theory (entity versus incremental) the influence of consumers' implicit personality theory on transference was considered within the brand-extension context. As expected, the amount of transference differed between those espousing entity and incremental theories. "Entity theorists" were much more likely to transfer feelings associated with the parent brand to the new extension than were "incremental theorists" who did not rely on prior brand information when forming evaluations of a new extension. This effect did not occur when perceived fit between the parent brand and the extension was high.

Regulatory elements of the floral homeotic gene AGAMOUS identified by phylogenetic footprinting and shadowing.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hong, R. L., Hamaguchi, L., Busch, M. A., and Weigel, D.

2003-06-01

OAK-B135 In Arabidopsis thaliana, cis-regulatory sequences of the floral homeotic gene AGAMOUS (AG) are located in the second intron. This 3 kb intron contains binding sites for two direct activators of AG, LEAFY (LFY) and WUSCHEL (WUS), along with other putative regulatory elements. We have used phylogenetic footprinting and the related technique of phylogenetic shadowing to identify putative cis-regulatory elements in this intron. Among 29 Brassicaceae, several other motifs, but not the LFY and WUS binding sites previously identified, are largely invariant. Using reporter gene analyses, we tested six of these motifs and found that they are all functionally importantmore » for activity of AG regulatory sequences in A. thaliana. Although there is little obvious sequence similarity outside the Brassicaceae, the intron from cucumber AG has at least partial activity in A. thaliana. Our studies underscore the value of the comparative approach as a tool that complements gene-by-gene promoter dissection, but also highlight that sequence-based studies alone are insufficient for a complete identification of cis-regulatory sites.« less

Effects of Yogurt Containing Fermented Pepper Juice on the Body Fat and Cholesterol Level in High Fat and High Cholesterol Diet Fed Rat.

PubMed

Yeon, Su-Jung; Hong, Go-Eun; Kim, Chang-Kyu; Park, Woo Joon; Kim, Soo-Ki; Lee, Chi-Ho

2015-01-01

This experiment investigated whether yogurt containing fermented pepper juice (FPJY) affects cholesterol level in high fat and high cholesterol diet (HFCD) fed rat. Twenty five Sprague-Dawley male rats of 7 wk were divided into 5 groups, and fed following diets for 9 wk; CON (control diet), HFCD (HFCD), PY (HFCD supplemented with 2% of plain yogurt), LFY (HFCD supplemented with 2% of FPJY), and HFY (HFCD supplemented with 5% of FPJY). In the LFY group, hepatic total lipid level decreased significantly compared to the HFCD group (p<0.05). Serum HDL cholesterol level tended to increase and hepatic total cholesterol level decreased and were comparable to the CON group (p>0.05). In HFY group, body weight and hepatic total lipid level significantly decreased over the HFCD group (p<0.05). Serum and hepatic total cholesterol level, kidney, and body fat weights decreased, and were compared to the CON group (p>0.05). Liver weight decreased as FPJY content was increased. Results suggested FPJY would inhibit organ hypertrophy and accumulation of body fat, hepatic lipid, and cholesterol in HFCD fed rat.

Hybrid Teaching in Extension: Learning at the Crossroads

ERIC Educational Resources Information Center

Hino, Jeff; Kahn, Cub

2016-01-01

Extension clients' learning preferences are changing, with many increasingly going online for educational content. In response, Oregon State University Extension pilot tested a training program for Extension educators to explore hybrid teaching--a methodology that could provide more flexible access to a wider audience. Hybrid teaching offers a…

Australian National University Science Extension Day

ERIC Educational Resources Information Center

Fletcher, Sarah

2016-01-01

The first Australian National University (ANU) Science Extension Day was held on September 8, 2015. The ANU Science Extension Day is a project that was initiated by Theodore Primary School (ACT) and developed by Theodore Primary, Calwell High School, Science Educators Association of the ACT (SEA*ACT), and the ANU. The project was developed with a…

Novel quantum phase transition from bounded to extensive entanglement

PubMed Central

Zhang, Zhao; Ahmadain, Amr

2017-01-01

The nature of entanglement in many-body systems is a focus of intense research with the observation that entanglement holds interesting information about quantum correlations in large systems and their relation to phase transitions. In particular, it is well known that although generic, many-body states have large, extensive entropy, ground states of reasonable local Hamiltonians carry much smaller entropy, often associated with the boundary length through the so-called area law. Here we introduce a continuous family of frustration-free Hamiltonians with exactly solvable ground states and uncover a remarkable quantum phase transition whereby the entanglement scaling changes from area law into extensively large entropy. This transition shows that entanglement in many-body systems may be enhanced under special circumstances with a potential for generating “useful” entanglement for the purpose of quantum computing and that the full implications of locality and its restrictions on possible ground states may hold further surprises. PMID:28461464

Novel quantum phase transition from bounded to extensive entanglement.

PubMed

Zhang, Zhao; Ahmadain, Amr; Klich, Israel

2017-05-16

The nature of entanglement in many-body systems is a focus of intense research with the observation that entanglement holds interesting information about quantum correlations in large systems and their relation to phase transitions. In particular, it is well known that although generic, many-body states have large, extensive entropy, ground states of reasonable local Hamiltonians carry much smaller entropy, often associated with the boundary length through the so-called area law. Here we introduce a continuous family of frustration-free Hamiltonians with exactly solvable ground states and uncover a remarkable quantum phase transition whereby the entanglement scaling changes from area law into extensively large entropy. This transition shows that entanglement in many-body systems may be enhanced under special circumstances with a potential for generating "useful" entanglement for the purpose of quantum computing and that the full implications of locality and its restrictions on possible ground states may hold further surprises.

Transient Side Load Analysis of Out-of-Round Film-Cooled Nozzle Extensions

NASA Technical Reports Server (NTRS)

Wang, Ten-See; Lin, Jeff; Ruf, Joe; Guidos, Mike

2012-01-01

There was interest in understanding the impact of out-of-round nozzle extension on the nozzle side load during transient startup operations. The out-of-round nozzle extension could be the result of asymmetric internal stresses, deformation induced by previous tests, and asymmetric loads induced by hardware attached to the nozzle. The objective of this study was therefore to computationally investigate the effect of out-of-round nozzle extension on the nozzle side loads during an engine startup transient. The rocket engine studied encompasses a regeneratively cooled chamber and nozzle, along with a film cooled nozzle extension. The computational methodology is based on an unstructured-grid, pressure-based computational fluid dynamics formulation, and transient inlet boundary flow properties derived from an engine system simulation. Six three-dimensional cases were performed with the out-of-roundness achieved by three different degrees of ovalization, elongated on lateral y and z axes: one slightly out-of-round, one more out-of-round, and one significantly out-of-round. The results show that the separation line jump was the primary source of the peak side loads. Comparing to the peak side load of the perfectly round nozzle, the peak side loads increased for the slightly and more ovalized nozzle extensions, and either increased or decreased for the two significantly ovalized nozzle extensions. A theory based on the counteraction of the flow destabilizing effect of an exacerbated asymmetrical flow caused by a lower degree of ovalization, and the flow stabilizing effect of a more symmetrical flow, created also by ovalization, is presented to explain the observations obtained in this effort.

Expanding the Reach of Extension through Social Media

ERIC Educational Resources Information Center

Gharis, Lauri W.; Bardon, Robert E.; Evans, Jennifer L.; Hubbard, William G.; Taylor, Eric

2014-01-01

With increasing numbers of the public using social media applications, Extension professionals have the ability to apply these same tools to connect with their clients. This article demonstrates how a social media toolset can be employed by Extension professionals by identifying how Extension professionals are currently using social media,…

33 CFR 151.1513 - Extension of compliance date.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Extension of compliance date. 151.1513 Section 151.1513 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY... basis for the extension will be promptly posted on the Internet. Extensions will be for no longer than...

33 CFR 151.1513 - Extension of compliance date.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Extension of compliance date. 151.1513 Section 151.1513 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY... basis for the extension will be promptly posted on the Internet. Extensions will be for no longer than...

33 CFR 151.1513 - Extension of compliance date.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Extension of compliance date. 151.1513 Section 151.1513 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY... basis for the extension will be promptly posted on the Internet. Extensions will be for no longer than...

Redefining the Concept of Learning in Cooperative Extension

ERIC Educational Resources Information Center

Worker, Steven M.; Ouellette, Kristy L.; Maille, Alexa

2017-01-01

For Extension educational programs to meet the educational needs of today's youths, families, and communities, Extension needs to expand "what counts" as learning. The purpose of this article is to define learning in the context of Extension. We summarize key aspects of the educational research literature by comparing two prevailing…

Strategic Directions for Extension Health and Wellness Programs

ERIC Educational Resources Information Center

Rodgers, Michelle; Braun, Bonnie

2015-01-01

The new Cooperative Extension National Framework for Health and Wellness is a tool to help Extension systematically address the programmatic area of health and wellness at the individual, community, environmental, and policy levels. Key strategies of the framework tool are provided and suggestions for ways that Extension can use this framework…

Single polymer dynamics under large amplitude oscillatory extension

NASA Astrophysics Data System (ADS)

Zhou, Yuecheng; Schroeder, Charles M.

2016-09-01

Understanding the conformational dynamics of polymers in time-dependent flows is of key importance for controlling materials properties during processing. Despite this importance, however, it has been challenging to study polymer dynamics in controlled time-dependent or oscillatory extensional flows. In this work, we study the dynamics of single polymers in large-amplitude oscillatory extension (LAOE) using a combination of experiments and Brownian dynamics (BD) simulations. Two-dimensional LAOE flow is generated using a feedback-controlled stagnation point device known as the Stokes trap, thereby generating an oscillatory planar extensional flow with alternating principal axes of extension and compression. Our results show that polymers experience periodic cycles of compression, reorientation, and extension in LAOE, and dynamics are generally governed by a dimensionless flow strength (Weissenberg number Wi) and dimensionless frequency (Deborah number De). Single molecule experiments are compared to BD simulations with and without intramolecular hydrodynamic interactions (HI) and excluded volume (EV) interactions, and good agreement is obtained across a range of parameters. Moreover, transient bulk stress in LAOE is determined from simulations using the Kramers relation, which reveals interesting and unique rheological signatures for this time-dependent flow. We further construct a series of single polymer stretch-flow rate curves (defined as single molecule Lissajous curves) as a function of Wi and De, and we observe qualitatively different dynamic signatures (butterfly, bow tie, arch, and line shapes) across the two-dimensional Pipkin space defined by Wi and De. Finally, polymer dynamics spanning from the linear to nonlinear response regimes are interpreted in the context of accumulated fluid strain in LAOE.

A Model for Evaluating eXtension Communities of Practice

ERIC Educational Resources Information Center

Kelsey, Kathleen D.; Stafne, Eric T.

2012-01-01

As Americans shift their work and leisure activities online, Extension seeks to remain viable by delivering programs through a website known as eXtension. eXtension is predicated on the voluntary labor of Extension specialists and educators who form Communities of Practice to create and deliver content through the website. Evaluation of eXtension…

Extension Online: Utilizing Technology to Enhance Educational Outreach

ERIC Educational Resources Information Center

Green, Stephen

2012-01-01

Extension Online is an Internet-based online course platform that enables the Texas AgriLife Extension Service's Family Development and Resource Management (FDRM) unit to reach tens of thousands of users across the U.S. annually with research-based information. This article introduces readers to Extension Online by describing the history of its…

Effects of Acute Fatigue of the Hip Flexor Muscles on Hamstring Muscle Extensibility.

PubMed

Muyor, José M; Arrabal-Campos, Francisco M

2016-12-01

The purpose of the present study was to evaluate the influence of acute fatigue of the hip flexor muscles on scores attained in tests frequently used in literature to measure hamstring muscle extensibility, namely the passive straight leg raise (PSLR), active straight leg raise (ASLR), passive knee extension (PKE), active knee extension (AKE), sit-and-reach (SR) and toe-touch (TT) tests. A total of seventy-five healthy and recreationally active adults voluntarily participated in this study. To reach fatigue, the participants actively lifted their legs alternately as many times as possible. In the passive tests, the results were 7.10 ± 5.21° and 5.68 ± 4.54° higher (p < 0.01) for PSLR and PKE tests, respectively, after acute fatigue. However, in the ASLR test, the results were lower post-fatigue than pre-fatigue (mean difference = -5.30° ± 9.51°; p < 0.01). The AKE, SR and TT tests did not show significant differences between pre- and post-fatigue (p > 0.05). Moderate (r = 0.40) to high (r = 0.97) correlation coefficients were found, which were statistically significant among all the measured flexibility tests both pre- and post-fatigue. In conclusion, the active implication of the hip flexor muscles until reaching fatigue had acute influences on the results of the PSLR, PKE and ASLR tests, but not on the results of the AKE, SR and TT tests. It is recommended to use the AKE test to assess hamstring muscle extensibility in situations where athletes show fatigue in their hip flexor muscles.

77 FR 17464 - Agency Information Collection Extension

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-26

... DEPARTMENT OF ENERGY U.S. Energy Information Administration Agency Information Collection Extension AGENCY: U.S. Energy Information Administration (EIA), Department of Energy. ACTION: Agency Information Collection Activities: Information Collection Extension; Notice and Request for Comments. SUMMARY...

Innovative Extension Models and Smallholders: How ICT platforms can Deliver Timely Information to Farmers in India.

NASA Astrophysics Data System (ADS)

Nagothu, U. S.

2016-12-01

Agricultural extension services, among others, contribute to improving rural livelihoods and enhancing economic development. Knowledge development and transfer from the cognitive science point of view, is about, how farmers use and apply their experiential knowledge as well as acquired new knowledge to solve new problems. This depends on the models adopted, the way knowledge is generated and delivered. New extension models based on ICT platforms and smart phones are promising. Results from a 5-year project (www.climaadapt.org) in India shows that farmer led-on farm validations of technologies and knowledge exchange through ICT based platforms outperformed state operated linear extension programs. Innovation here depends on the connectivity, net-working between stakeholders that are involved in generating, transferring and using the knowledge. Key words: Smallholders, Knowledge, Extension, Innovation, India

77 FR 23704 - Agency Information Collection Extension

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-20

... DEPARTMENT OF ENERGY U.S. Energy Information Administration Agency Information Collection Extension AGENCY: U.S. Energy Information Administration (EIA), Department of Energy (DOE). ACTION: Agency Information Collection Activities: Information Collection Extension; Notice and Request for Comments. SUMMARY...

78 FR 13333 - Agency Information Collection Extension

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-27

... DEPARTMENT OF ENERGY U.S. Energy Information Administration Agency Information Collection Extension AGENCY: U.S. Energy Information Administration (EIA), Department of Energy (DOE). ACTION: Agency Information Collection Activities: Information Collection Extension; Notice and Request for Comments. SUMMARY...

Landform and terrain shape indices are related to oak site index in the Missouri Ozarks

Treesearch

Jason L. Villwock; John M. Kabrick; W. Henry McNab; Daniel C. Dey

2011-01-01

In the Southern Appalachians, metrics for quantifying the geometric shape of the land surface (terrain shape index or "tsi") and of the landform (land form index or "lfi") were developed and found to be correlated to yellow-poplar site index. However, the utility of these metrics for predicting site index for oaks in the Ozark Highlands has not been...

Why and How Textbooks Should Encourage Extensive Reading

ERIC Educational Resources Information Center

Brown, Dale

2009-01-01

Extensive reading is believed to have considerable benefits for learners both in terms of learning gains and motivation and seems to be becoming ever more popular in the ELT world. So far, however, there seems to be almost no integration of extensive reading and textbooks. This article argues that textbooks should be encouraging extensive reading,…

ANTLR Tree Grammar Generator and Extensions

NASA Technical Reports Server (NTRS)

Craymer, Loring

2005-01-01

A computer program implements two extensions of ANTLR (Another Tool for Language Recognition), which is a set of software tools for translating source codes between different computing languages. ANTLR supports predicated- LL(k) lexer and parser grammars, a notation for annotating parser grammars to direct tree construction, and predicated tree grammars. [ LL(k) signifies left-right, leftmost derivation with k tokens of look-ahead, referring to certain characteristics of a grammar.] One of the extensions is a syntax for tree transformations. The other extension is the generation of tree grammars from annotated parser or input tree grammars. These extensions can simplify the process of generating source-to-source language translators and they make possible an approach, called "polyphase parsing," to translation between computing languages. The typical approach to translator development is to identify high-level semantic constructs such as "expressions," "declarations," and "definitions" as fundamental building blocks in the grammar specification used for language recognition. The polyphase approach is to lump ambiguous syntactic constructs during parsing and then disambiguate the alternatives in subsequent tree transformation passes. Polyphase parsing is believed to be useful for generating efficient recognizers for C++ and other languages that, like C++, have significant ambiguities.

Road Cycling and Mountain Biking Produces Adaptations on the Spine and Hamstring Extensibility.

PubMed

Muyor, J M; Zabala, M

2016-01-01

The purposes of this study were as follows: 1) to analyse the influence of training in road cycling or cross-country mountain biking on sagittal spinal curvatures, pelvic tilt and trunk inclination in cyclists of both cycling modalities; 2) to evaluate the specific spinal posture and pelvic tilt adopted on the road bicycle and cross-country mountain bike; and 3) to compare the spinal sagittal capacity of flexion and pelvic tilt mobility as well as hamstring muscle extensibility among road cyclists, cross-country mountain bikers and non-cyclists. Thirty matched road cyclists, 30 mountain bikers and 30 non-cyclists participated in this study. The road cyclists showed significantly greater thoracic kyphosis and trunk inclination than did the mountain bikers and non-cyclists in a standing posture. On the bicycle, the road bicycling posture was characterised by greater lumbar flexion and more significant anterior pelvic tilt and trunk inclination compared with the mountain biking posture. The thoracic spine was more flexed in mountain biking than in road cycling. Road cyclists had significantly greater hamstring muscle extensibility in the active knee extension test, and showed greater anterior pelvic tilt and trunk inclination capacity in the sit-and-reach test, compared with mountain bikers and non-cyclists. © Georg Thieme Verlag KG Stuttgart · New York.

A Collaborative Extensible User Environment for Simulation and Knowledge Management

DOE Office of Scientific and Technical Information (OSTI.GOV)

Freedman, Vicky L.; Lansing, Carina S.; Porter, Ellen A.

2015-06-01

In scientific simulation, scientists use measured data to create numerical models, execute simulations and analyze results from advanced simulators executing on high performance computing platforms. This process usually requires a team of scientists collaborating on data collection, model creation and analysis, and on authorship of publications and data. This paper shows that scientific teams can benefit from a user environment called Akuna that permits subsurface scientists in disparate locations to collaborate on numerical modeling and analysis projects. The Akuna user environment is built on the Velo framework that provides both a rich client environment for conducting and analyzing simulations andmore » a Web environment for data sharing and annotation. Akuna is an extensible toolset that integrates with Velo, and is designed to support any type of simulator. This is achieved through data-driven user interface generation, use of a customizable knowledge management platform, and an extensible framework for simulation execution, monitoring and analysis. This paper describes how the customized Velo content management system and the Akuna toolset are used to integrate and enhance an effective collaborative research and application environment. The extensible architecture of Akuna is also described and demonstrates its usage for creation and execution of a 3D subsurface simulation.« less

Extension Service :: Calendar

Science.gov Websites

Month view List view Extension Service details submit new event to this calendar basic view Export as 9:00am Linn & Benton Master Food Preserver Training 9:00am Master Food Preserver Volunteer Training Program - Linn and Benton Counties 1:00pm Linn County Master Gardener Association Board Meeting 2

"Let's Talk": Collaboration between Family and Consumer Sciences Extension Personnel and Teachers

ERIC Educational Resources Information Center

Abdul-Rahman, Fahzy; Bartley, Sharon Jeffcoat; Cummings, Merrilyn; O'Brien, David

2013-01-01

Interactive meetings between New Mexico Family and Consumer Sciences (FCS) teachers and Extension personnel (county Home Economics agents and state FCS specialists) were conducted to promote collaboration between the two parties. Based on pre- and post-meeting surveys, both parties showed similarities in almost all perceptions and expectations…

Mapping Extension's Networks: Using Social Network Analysis to Explore Extension's Outreach

ERIC Educational Resources Information Center

Bartholomay, Tom; Chazdon, Scott; Marczak, Mary S.; Walker, Kathrin C.

2011-01-01

The University of Minnesota Extension conducted a social network analysis (SNA) to examine its outreach to organizations external to the University of Minnesota. The study found that its outreach network was both broad in its reach and strong in its connections. The study found that SNA offers a unique method for describing and measuring Extension…

Facilitating protein solubility by use of peptide extensions

DOEpatents

Freimuth, Paul I; Zhang, Yian-Biao; Howitt, Jason

2013-09-17

Expression vectors for expression of a protein or polypeptide of interest as a fusion product composed of the protein or polypeptide of interest fused at one terminus to a solubility enhancing peptide extension are provided. Sequences encoding the peptide extensions are provided. The invention further comprises antibodies which bind specifically to one or more of the solubility enhancing peptide extensions.

PRINCESS: Privacy-protecting Rare disease International Network Collaboration via Encryption through Software guard extensionS

PubMed Central

Chen, Feng; Wang, Shuang; Jiang, Xiaoqian; Ding, Sijie; Lu, Yao; Kim, Jihoon; Sahinalp, S. Cenk; Shimizu, Chisato; Burns, Jane C.; Wright, Victoria J.; Png, Eileen; Hibberd, Martin L.; Lloyd, David D.; Yang, Hai; Telenti, Amalio; Bloss, Cinnamon S.; Fox, Dov; Lauter, Kristin; Ohno-Machado, Lucila

2017-01-01

Abstract Motivation: We introduce PRINCESS, a privacy-preserving international collaboration framework for analyzing rare disease genetic data that are distributed across different continents. PRINCESS leverages Software Guard Extensions (SGX) and hardware for trustworthy computation. Unlike a traditional international collaboration model, where individual-level patient DNA are physically centralized at a single site, PRINCESS performs a secure and distributed computation over encrypted data, fulfilling institutional policies and regulations for protected health information. Results: To demonstrate PRINCESS’ performance and feasibility, we conducted a family-based allelic association study for Kawasaki Disease, with data hosted in three different continents. The experimental results show that PRINCESS provides secure and accurate analyses much faster than alternative solutions, such as homomorphic encryption and garbled circuits (over 40 000× faster). Availability and Implementation: https://github.com/achenfengb/PRINCESS_opensource Contact: shw070@ucsd.edu Supplementary information: Supplementary data are available at Bioinformatics online. PMID:28065902

Effects of whole-plant corn silage hybrid type on intake, digestion, ruminal fermentation, and lactation performance by dairy cows through a meta-analysis.

PubMed

Ferraretto, L F; Shaver, R D

2015-04-01

Understanding the effect of whole-plant corn silage (WPCS) hybrids in dairy cattle diets may allow for better decisions on hybrid selection by dairy producers, as well as indicate potential strategies for the seed corn industry with regard to WPCS hybrids. Therefore, the objective of this study was to perform a meta-analysis using literature data on the effects of WPCS hybrid type on intake, digestibility, rumen fermentation, and lactation performance by dairy cows. The meta-analysis was performed using a data set of 162 treatment means from 48 peer-reviewed articles published between 1995 and 2014. Hybrids were divided into 3 categories before analysis. Comparative analysis of WPCS hybrid types differing in stalk characteristics were in 4 categories: conventional, dual-purpose, isogenic, or low-normal fiber digestibility (CONS), brown midrib (BMR), hybrids with greater NDF but lower lignin (%NDF) contents or high in vitro NDF digestibility (HFD), and leafy (LFY). Hybrid types differing in kernel characteristics were in 4 categories: conventional or yellow dent (CONG), NutriDense (ND), high oil (HO), and waxy. Genetically modified (GM) hybrids were compared with their genetically similar non-biotech counterpart (ISO). Except for lower lignin content for BMR and lower starch content for HFD than CONS and LFY, silage nutrient composition was similar among hybrids of different stalk types. A 1.1 kg/d greater intake of DM and 1.5 and 0.05 kg/d greater milk and protein yields, respectively, were observed for BMR compared with CONS and LFY. Likewise, DMI and milk yield were greater for HFD than CONS, but the magnitude of the difference was smaller. Total-tract NDF digestibility was greater, but starch digestibility was reduced, for BMR and HFD compared with CONS or LFY. Silage nutrient composition was similar for hybrids of varied kernel characteristics, except for lower CP and EE content for CONG than ND and HO. Feeding HO WPCS to dairy cows decreased milk fat content

Holographically viable extensions of topologically massive and minimal massive gravity?

NASA Astrophysics Data System (ADS)

Altas, Emel; Tekin, Bayram

2016-01-01

Recently [E. Bergshoeff et al., Classical Quantum Gravity 31, 145008 (2014)], an extension of the topologically massive gravity (TMG) in 2 +1 dimensions, dubbed as minimal massive gravity (MMG), which is free of the bulk-boundary unitarity clash that inflicts the former theory and all the other known three-dimensional theories, was found. Field equations of MMG differ from those of TMG at quadratic terms in the curvature that do not come from the variation of an action depending on the metric alone. Here we show that MMG is a unique theory and there does not exist a deformation of TMG or MMG at the cubic and quartic order (and beyond) in the curvature that is consistent at the level of the field equations. The only extension of TMG with the desired bulk and boundary properties having a single massive degree of freedom is MMG.

Lubin-Tate extensions, an elementary approach

NASA Astrophysics Data System (ADS)

Ershov, Yu L.

2007-12-01

We give an elementary proof of the assertion that the Lubin-Tate extension L\\ge K is an Abelian extension whose Galois group is isomorphic to U_K/N_{L/K}(U_L) for arbitrary fields K that have Henselian discrete valuation rings with finite residue fields. The term `elementary' only means that the proofs are algebraic (that is, no transcedental methods are used [1], pp. 327, 332).

Supersymmetric extensions of K field theories

NASA Astrophysics Data System (ADS)

Adam, C.; Queiruga, J. M.; Sanchez-Guillen, J.; Wereszczynski, A.

2012-02-01

We review the recently developed supersymmetric extensions of field theories with non-standard kinetic terms (so-called K field theories) in two an three dimensions. Further, we study the issue of topological defect formation in these supersymmetric theories. Specifically, we find supersymmetric K field theories which support topological kinks in 1+1 dimensions as well as supersymmetric extensions of the baby Skyrme model for arbitrary nonnegative potentials in 2+1 dimensions.

75 FR 77663 - Information Collection Extension Request

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-13

... DEPARTMENT OF LABOR Office of the Secretary Information Collection Extension Request ACTION... agencies with an opportunity to comment on information collection extension request in accordance with the... collection of the Compliance Information Report--29 CFR part 31 (Title VI of the Civil Rights Act...

Late Miocene extension partitioning in the eastern Betics: from W- to E-directed extension between the Sorbas and Vera basins (SE Spain).

NASA Astrophysics Data System (ADS)

Giaconia, Flavio; Booth-Rea, Guillermo; Martínez-Martínez, Jose Miguel; Azañon, Jose Miguel

2014-05-01

Late Miocene westward-directed extension in the Betics produced elongated core-complexes like Sierra Nevada and the Sierra de Filabres, tilted-block domains and associated basins. This extension represents the superficial manifestation of the rupture of the Tethyan slab and associated edge delamination along a lithospheric transform fault beneath the northern branch of the Gibraltar Arc orogenic system. However, crustal thinning at the eastern Betics occurs progressively towards the east suggesting an eastward-directed extension, probably related to the late Miocene opening of the Algero-Balearic basin. In order to define the kinematics and timing of such a heterogeneous extension at the eastern Betics we have carefully mapped a key area at the transition between the Sorbas and Vera basins. Field data indicate that extension in the area started at the southern margin of the Vera basin during the Serravallian (13.8 Ma) and continued until the Tortonian (approximately 8 Ma). This extension was characterized by a set of NE- to E-directed normal faults to the east, in the Vera basin, and a set of SW-directed normal faults to the west, towards the Sorbas basin. This opposite-directed extension is segmented by E-W to WNW-ESE strike-slip faults like the North Cabrera dextral transfer fault that accommodates NE- to E-directed extension to the north and SW-directed extension to the south. This structure resulted in westward tilted blocks that lead to Serravallian-Tortonian depocenters deepening towards the east at the Vera basin along the northern side of Sierra Cabrera. Meanwhile, at the western termination of Sierra Cabrera, westward-directed extension migrated SW-ward forming the Sorbas basin during the Tortonian (approximately 9-7.24 Ma). This extension was characterized by a listric fan of SW-directed normal faults highly segmented by E-W to NE-SW transfer. This extensional system produced tiled-blocks defining a Tortonian depocenter at the eastern margin of the Sorbas

A study of FM threshold extension techniques

NASA Technical Reports Server (NTRS)

Arndt, G. D.; Loch, F. J.

1972-01-01

The characteristics of three postdetection threshold extension techniques are evaluated with respect to the ability of such techniques to improve the performance of a phase lock loop demodulator. These techniques include impulse-noise elimination, signal correlation for the detection of impulse noise, and delta modulation signal processing. Experimental results from signal to noise ratio data and bit error rate data indicate that a 2- to 3-decibel threshold extension is readily achievable by using the various techniques. This threshold improvement is in addition to the threshold extension that is usually achieved through the use of a phase lock loop demodulator.

Major advances in extension education programs in dairy production.

PubMed

Chase, L E; Ely, L O; Hutjens, M F

2006-04-01

The dairy industry has seen structural changes in the last 25 yr that have an impact on extension programming. The number of cows in the United States has decreased by 17%, whereas the number of dairy farms has decreased by 74%. The average milk production per cow has increased from 5,394 to 8,599 kg/lactation. Even though there are fewer farms, dairy farm managers are asking for more specific and targeted information. The extension resources available have also decreased during this period. Because of these changes, shifts have taken place in extension programming and staffing. A key change has been a shift to subject matter-targeted programs and workshops. Extension has also incorporated and expanded use of the Internet. Discussion groups, subject matter courses, and searchable databases are examples of Internet use. There will be continuing shifts in the demographics of the US dairy industry that will influence future extension efforts. It is also probable that fewer extension professionals will be available to provide programming due to changes in funding sources at national, state, and local levels. Future shifts in extension programming will be needed to provide the information needs of the industry with a smaller number of extension workers.

A description of Seismicity based on Non-extensive Statistical Physics: An introduction to Non-extensive Statistical Seismology.

NASA Astrophysics Data System (ADS)

Vallianatos, Filippos

2015-04-01

Despite the extreme complexity that characterizes earthquake generation process, simple phenomenology seems to apply in the collective properties of seismicity. The best known is the Gutenberg-Richter relation. Short and long-term clustering, power-law scaling and scale-invariance have been exhibited in the spatio-temporal evolution of seismicity providing evidence for earthquakes as a nonlinear dynamic process. Regarding the physics of "many" earthquakes and how this can be derived from first principles, one may wonder, how can the collective properties of a set formed by all earthquakes in a given region, be derived and how does the structure of seismicity depend on its elementary constituents - the earthquakes? What are these properties? The physics of many earthquakes has to be studied with a different approach than the physics of one earthquake making the use of statistical physics necessary to understand the collective properties of earthquakes. Then a natural question arises. What type of statistical physics is appropriate to commonly describe effects from the microscale and crack opening level to the level of large earthquakes? An answer to the previous question could be non-extensive statistical physics, introduced by Tsallis (1988), as the appropriate methodological tool to describe entities with (multi) fractal distributions of their elements and where long-range interactions or intermittency are important, as in fracturing phenomena and earthquakes. In the present work, we review some fundamental properties of earthquake physics and how these are derived by means of non-extensive statistical physics. The aim is to understand aspects of the underlying physics that lead to the evolution of the earthquake phenomenon introducing the new topic of non-extensive statistical seismology. This research has been funded by the European Union (European Social Fund) and Greek national resources under the framework of the "THALES Program: SEISMO FEAR HELLARC" project