Science.gov

Sample records for long-term interest rates

  1. 18 CFR 367.4270 - Account 427, Interest on long-term debt.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... on long-term debt. 367.4270 Section 367.4270 Conservation of Power and Water Resources FEDERAL ENERGY..., Interest on long-term debt. (a) This account must include the amount of interest on outstanding long-term..., Other long-term debt (§ 367.2240). (b) This account must be kept or supported so as to show the...

  2. 18 CFR 367.4270 - Account 427, Interest on long-term debt.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... on long-term debt. 367.4270 Section 367.4270 Conservation of Power and Water Resources FEDERAL ENERGY..., Interest on long-term debt. (a) This account must include the amount of interest on outstanding long-term..., Other long-term debt (§ 367.2240). (b) This account must be kept or supported so as to show the...

  3. 18 CFR 367.4270 - Account 427, Interest on long-term debt.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... on long-term debt. 367.4270 Section 367.4270 Conservation of Power and Water Resources FEDERAL ENERGY..., Interest on long-term debt. (a) This account must include the amount of interest on outstanding long-term..., Other long-term debt (§ 367.2240). (b) This account must be kept or supported so as to show the...

  4. 18 CFR 367.4270 - Account 427, Interest on long-term debt.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... on long-term debt. 367.4270 Section 367.4270 Conservation of Power and Water Resources FEDERAL ENERGY..., Interest on long-term debt. (a) This account must include the amount of interest on outstanding long-term..., Other long-term debt (§ 367.2240). (b) This account must be kept or supported so as to show the...

  5. 17 CFR 256.427 - Interest on long-term debt.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Interest on long-term debt... UTILITY HOLDING COMPANY ACT OF 1935 Income and Expense Accounts § 256.427 Interest on long-term debt. This account shall include the amount of interest accrued on outstanding long-term debt owed by the...

  6. 17 CFR 256.427 - Interest on long-term debt.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Interest on long-term debt... UTILITY HOLDING COMPANY ACT OF 1935 Income and Expense Accounts § 256.427 Interest on long-term debt. This account shall include the amount of interest accrued on outstanding long-term debt owed by the...

  7. Interest in Long-Term Care among Health Services Administration Students

    ERIC Educational Resources Information Center

    Temple, April; Thompson, Jon M.

    2011-01-01

    The aging of the population has created increased opportunities for health administrators in long-term care. This study consisted of a cross-sectional survey of 68 undergraduate health services administration students to explore factors related to interest in a career in long-term care administration. One third expressed interest working in the…

  8. Determining long-term regional erosion rates using impact craters

    NASA Astrophysics Data System (ADS)

    Hergarten, Stefan; Kenkmann, Thomas

    2015-04-01

    More than 300,000 impact craters have been found on Mars, while the surface of Moon's highlands is even saturated with craters. In contrast, only 184 impact craters have been confirmed on Earth so far with only 125 of them exposed at the surface. The spatial distribution of these impact craters is highly inhomogeneous. Beside the large variation in the age of the crust, consumption of craters by erosion and burial by sediments are the main actors being responsible for the quite small and inhomogeneous crater record. In this study we present a novel approach to infer long-term average erosion rates at regional scales from the terrestrial crater inventory. The basic idea behind this approach is a dynamic equilibrium between the production of new craters and their consumption by erosion. It is assumed that each crater remains detectable until the total erosion after the impact exceeds a characteristic depth depending on the crater's diameter. Combining this model with the terrestrial crater production rate, i.e., the number of craters per unit area and time as a function of their diameter, allows for a prediction of the expected number of craters in a given region as a function of the erosion rate. Using the real crater inventory, this relationship can be inverted to determine the regional long-term erosion rate and its statistical uncertainty. A limitation by the finite age of the crust can also be taken into account. Applying the method to the Colorado Plateau and the Deccan Traps, both being regions with a distinct geological history, yields erosion rates in excellent agreement with those obtained by other, more laborious methods. However, these rates are formally exposed to large statistical uncertainties due to the small number of impact craters. As higher crater densities are related to lower erosion rates, smaller statistical errors can be expected when large regions in old parts of the crust are considered. Very low long-term erosion rates of less than 4

  9. Long-Term Volumetric Eruption Rates and Magma Budgets

    SciTech Connect

    Scott M. White Dept. Geological Sciences University of South Carolina Columbia, SC 29208; Joy A. Crisp Jet Propulsion Laboratory, California Institute of Technology Pasadena, CA 91109; Frank J. Spera Dept. Earth Science University of California, Santa Barbara Santa Barbara, CA 93106

    2005-01-01

    A global compilation of 170 time-averaged volumetric volcanic output rates (Qe) is evaluated in terms of composition and petrotectonic setting to advance the understanding of long-term rates of magma generation and eruption on Earth. Repose periods between successive eruptions at a given site and intrusive:extrusive ratios were compiled for selected volcanic centers where long-term (>104 years) data were available. More silicic compositions, rhyolites and andesites, have a more limited range of eruption rates than basalts. Even when high Qe values contributed by flood basalts (9 ± 2 Å~ 10-1 km3/yr) are removed, there is a trend in decreasing average Qe with lava composition from basaltic eruptions (2.6 ± 1.0 Å~ 10-2 km3/yr) to andesites (2.3 ± 0.8 Å~ 10-3 km3/yr) and rhyolites (4.0 ± 1.4 Å~ 10-3 km3/yr). This trend is also seen in the difference between oceanic and continental settings, as eruptions on oceanic crust tend to be predominately basaltic. All of the volcanoes occurring in oceanic settings fail to have statistically different mean Qe and have an overall average of 2.8 ± 0.4 Å~ 10-2 km3/yr, excluding flood basalts. Likewise, all of the volcanoes on continental crust also fail to have statistically different mean Qe and have an overall average of 4.4 ± 0.8 Å~ 10-3 km3/yr. Flood basalts also form a distinctive class with an average Qe nearly two orders of magnitude higher than any other class. However, we have found no systematic evidence linking increased intrusive:extrusive ratios with lower volcanic rates. A simple heat balance analysis suggests that the preponderance of volcanic systems must be open magmatic systems with respect to heat and matter transport in order to maintain eruptible magma at shallow depth throughout the observed lifetime of the volcano. The empirical upper limit of Å`10-2 km3/yr for magma eruption rate in systems with relatively high intrusive:extrusive ratios may be a consequence of the fundamental parameters

  10. Long-term alteration of basaltic glass: Mechanisms and rates

    NASA Astrophysics Data System (ADS)

    Parruzot, Benjamin; Jollivet, Patrick; Rébiscoul, Diane; Gin, Stéphane

    2015-04-01

    The long-term behavior study of archaeological artifacts and natural minerals and glasses revealed discrepancies between laboratory and field data. For a better understanding of the cause of these discrepancies and to reinforce the use of basaltic glass as an analog for nuclear waste glasses, this study focuses on the determination of alteration rates and processes of synthetic basaltic glass in residual rate regime. Laboratory batch experiments were performed at high surface-to-volume ratios at 90 and 30 °C for more than 1000 days. In all the experiments, the residual rate regime was reached after about 6 months. The residual alteration rates at 30 and 90 °C were 4.0 ± 1.0 × 10-6 and 9.5 ± 3.2 × 10-6 g·m-2·d-1, respectively. At 90 °C, this residual alteration rate is five orders of magnitude lower than the forward alteration rate (0.8 g·m-2·d-1). Altered powders and monoliths were characterized by Transmission Electron Microscopy and Time-of-Flight Secondary Ion Mass Spectrometry. From glass core to solution, the altered materials are structured as follows: pristine glass, gel (corresponding to the palagonitic layer of natural glasses) and intergranular clays. To assess the passivating properties of this alteration film, we used solid characterization, an isotopically-tagged post-leaching experiment and the measurement of mobile species diffusion coefficients through the alteration film at different stages of reaction using various techniques (solution analysis and X-ray Reflectometry). These characterizations showed that the alteration film formed during residual rate alteration is passivating even without clogged porosity within the gel. Diffusion coefficients of water and alkali metals - respectively diffusing to and from the pristine glass - through the alteration film dropped from 10-20 to 10-19 m2·s-1 during the first alteration stages to 10-25 m2·s-1 in residual rate regime.

  11. Long term fault slip rates, distributed deformation rates and forecast of seismicity in the Iranian Plateau

    NASA Astrophysics Data System (ADS)

    Khodaverdian, A.; Zafarani, H.; Rahimian, M.

    2015-10-01

    In this paper, the long-term crustal flow of the Iranian Plateau is computed using a kinematic finite-element model (NeoKinema software). Based on the iterated weighted least squares method, the models are fitted to the newest data set of Iran including updated fault traces, geologic fault offset rates, geodetic benchmark velocities, principal stress directions, and velocity boundary conditions. We are successful to find the best kinematic model, in which geological slip rates, geodetic velocities, and interpolated stress directions are fitted at levels of 0.35, 1.0, and 1.0 datum standard deviation, respectively. The best fitted model, for the first time, provides long-term fault slip rates, velocity, and anelastic strain rate field in the Iranian Plateau from all available kinematic data. In order to verify the model, the estimates of fault slip rates are compared to slip rates from merely analyzing geodetic benchmark velocities or paleoseismological studies or published geological rates which have not been used in the model. Our estimated rates are all in the range of geodetic rates and are even more consistent with geological rates than previous GPS-based estimates. Using the selected model, long-term average seismicity maps and long-term moment rates are produced on the basis of the SHIFT hypothesis and previous global calibrations. Our kinematic model also provides a new constraint on ratio of seismic deformation to total deformation for different seismic zones of Iran. The resulting slip rates and the proposed seismic fraction of deformation provide the necessary input data for future time-dependent hazard studies in Iran. Moreover, spatial distribution and total number of strong (M > 6) and major (M > 7) earthquakes, which dominate the seismic hazard, are all compatible with the regional seismic catalog.

  12. Lunar gravity - A long-term Keplerian rate method

    NASA Technical Reports Server (NTRS)

    Ferrari, A. J.; Ananda, M. P.

    1977-01-01

    Nearside tracking data from Apollo subsatellites and Lunar Orbiter 5 are used to construct a model of the farside lunar gravity field. An indirect method of calculating the average effect of all the gravity anomalies which affect spacecraft orbits is reduced to a linear estimation problem by eliminating the integration of spacecraft dynamics. Doppler frequency shifts between the lunar satellite and earth-based tracking station are used to measure the line of sight velocity component between the orbiter and the tracker; gravity determination is then performed in a weighted least squares estimator which employs the orbital rates as data and formulates the normal equations using the associated Keplerian state. Simulations performed demonstrate that farside gravity features can be economically determined by use of gravity estimates obtained from long-period models of nearside orbiting tracks.

  13. Divergent microtubule assembly rates after short- versus long-term loss of end-modulating kinesins

    PubMed Central

    Wordeman, Linda; Decarreau, Justin; Vicente, Juan Jesus; Wagenbach, Michael

    2016-01-01

    Depletion of microtubule (MT) regulators can initiate stable alterations in MT assembly rates that affect chromosome instability and mitotic spindle function, but the manner by which cellular MT assembly rates can stably increase or decrease is not understood. To investigate this phenomenon, we measured the response of microtubule assembly to both rapid and long-term loss of MT regulators MCAK/Kif2C and Kif18A. Depletion of MCAK/Kif2C by siRNA stably decreases MT assembly rates in mitotic spindles, whereas depletion of Kif18A stably increases rates of assembly. Surprisingly, this is not phenocopied by rapid rapamycin-dependent relocalization of MCAK/Kif2C and Kif18A to the plasma membrane. Instead, this treatment yields opposite affects on MT assembly. Rapidly increased MT assembly rates are balanced by a decrease in nucleated microtubules, whereas nucleation appears to be maximal and limiting for decreased MT assembly rates and also for long-term treatments. We measured amplified tubulin synthesis during long-term depletion of MT regulators and hypothesize that this is the basis for different phenotypes arising from long-term versus rapid depletion of MT regulators. PMID:26912793

  14. Long-term shoreline retreat rates on Whidbey Island, Washington, USA

    NASA Astrophysics Data System (ADS)

    Rogers, Heather E.; Swanson, Terry W.; Stone, John O.

    2012-09-01

    Long-term retreat rates of Puget Sound's unconsolidated sediment shorelines have been difficult to quantify, and little systematic research has been completed to constrain retreat in this area. We put forward a new application of cosmogenic 10Be exposure dating to assess long-term shoreline retreat on Whidbey Island, WA by dating lag boulders exposed on the shore platform as the shoreline erodes. Production of 10Be in shoreline boulders is modulated by both tidal submergence and topographic shielding from the retreating bluff. By modeling the combined effect of these variables on 10Be production, the timing of exposure can be determined and used to calculate long-term (103-104 yr) bluff retreat rates. In rare cases, retreat rates are underestimated due to inherited 10Be. Within the study area, average retreat rates ranged between 0 and 8 cm yr- 1. Our results demonstrate the utility of cosmogenic nuclides for determining long-term shoreline retreat rates in areas with thick sediment cover, where large numbers of samples can be collected, and where the pre-depositional history of the boulders is uncomplicated.

  15. Estimating the long-term phosphorus accretion rate in the Everglades: A Bayesian approach with risk assessment

    NASA Astrophysics Data System (ADS)

    Qian, Song S.; Richardson, Curtis J.

    Using wetlands as a sink of nutrients, phosphorus in particular, is becoming an increasingly attractive alternative to conventional wastewater treatment technology. In this paper, we briefly review the mechanism of phosphorus retention in wetlands, as well as previous modeling efforts. A Bayesian method is then proposed for estimating the long-term phosphorus accretion rate in wetlands through a piecewise linear model of outflow phosphorus concentration and phosphorus mass loading rate. The Bayesian approach was used for its simplicity in computation and its ability to accurately represent uncertainty. Applied to an Everglades wetland, the Bayesian method not only produced the probability distribution of the long-term phosphorus accretion rate but also generated a relationship of acceptable level of ``risk'' and optimal phosphorus mass loading rate for the proposed constructed wetlands in south Florida. The latter is a useful representation of uncertainty which is of interest to decision makers.

  16. Decoupling of long-term exhumation and short-term erosion rates in the Sikkim Himalaya

    NASA Astrophysics Data System (ADS)

    Abrahami, Rachel; van der Beek, Peter; Huyghe, Pascale; Hardwick, Elisabeth; Carcaillet, Julien

    2016-01-01

    Understanding the relative strengths of tectonic and climatic forcing on erosion at different spatial and temporal scales is important to understand the evolution of orogenic topography. To address this question, we quantified exhumation rates at geological timescales and erosion rates at millennial timescales in modern river sands from 10 sub-catchments of the Tista River drainage basin in the Sikkim Himalaya (northeast India) using detrital apatite fission-track thermochronology and cosmogenic 10Be analyses, respectively. We compare these rates to several potential geomorphic or climatic forcing parameters. Our results show that millennial erosion rates are generally higher and spatially more variable than long-term exhumation rates in Sikkim. They also show strongly contrasting spatial patterns, suggesting that the processes controlling these rates are decoupled. At geological timescales, exhumation rates decrease from south to north, with rates up to 1.2 ± 0.6 mm/yr recorded in southwest Sikkim and as low as 0.5 ± 0.2 mm/yr in the northernmost catchment. Long-term exhumation rates do not correlate with any geomorphic or climatic parameter. We suggest they are tectonically controlled: high rates in southwest Sikkim may be linked to the building of the Lesser Himalaya Rangit Duplex, whereas low rates in north Sikkim are consistent with cessation of extensional exhumation along the South Tibetan Detachment after 13 Ma. The highest apparent erosion rates recorded by cosmogenic nuclides (˜5 mm/yr) occur in catchments spanning the Main Central Thrust Zone, but these appear to be strongly influenced by recent landsliding. High millennial erosion rates (1-2 mm/yr) also occur in north Sikkim and may be climatically driven through strong glacial inheritance of the landscape, as attested by high channel-steepness values close to the maximum extent of glaciers during the Last Glacial Maximum. In contrast, variations in rainfall rate do not seem to strongly influence

  17. Long-term effects of manipulated natal brood size on metabolic rate in zebra finches.

    PubMed

    Verhulst, Simon; Holveck, Marie-Jeanne; Riebel, Katharina

    2006-09-22

    Long-term effects of developmental conditions on health, longevity and other fitness components in humans are drawing increasing attention. In evolutionary ecology, such effects are of similar importance because of their role in the trade-off between quantity and quality of offspring. The central role of energy consumption is well documented for some long-term health effects in humans (e.g. obesity), but little is known of the long-term effects of rearing conditions on energy requirements later in life. We manipulated the rearing conditions in zebra finches (Taeniopygia guttata) using brood size manipulation and cross-fostering. It has previously been shown in this species that being reared in a large brood has negative fitness consequences, and that such effects are stronger in daughters than in sons. We show that, independent of mass, standard metabolic rate of 1-year-old birds was higher when they had been reared in a large brood, and this is to our knowledge the first demonstration of such an effect. Furthermore, the brood size effect was stronger in daughters than in sons. This suggests that metabolic efficiency may play a role in mediating the long-term fitness consequences of rearing conditions. PMID:17148435

  18. Long-term effects of manipulated natal brood size on metabolic rate in zebra finches

    PubMed Central

    Verhulst, Simon; Holveck, Marie-Jeanne; Riebel, Katharina

    2006-01-01

    Long-term effects of developmental conditions on health, longevity and other fitness components in humans are drawing increasing attention. In evolutionary ecology, such effects are of similar importance because of their role in the trade-off between quantity and quality of offspring. The central role of energy consumption is well documented for some long-term health effects in humans (e.g. obesity), but little is known of the long-term effects of rearing conditions on energy requirements later in life. We manipulated the rearing conditions in zebra finches (Taeniopygia guttata) using brood size manipulation and cross-fostering. It has previously been shown in this species that being reared in a large brood has negative fitness consequences, and that such effects are stronger in daughters than in sons. We show that, independent of mass, standard metabolic rate of 1-year-old birds was higher when they had been reared in a large brood, and this is to our knowledge the first demonstration of such an effect. Furthermore, the brood size effect was stronger in daughters than in sons. This suggests that metabolic efficiency may play a role in mediating the long-term fitness consequences of rearing conditions. PMID:17148435

  19. Long-term mindfulness training is associated with reliable differences in resting respiration rate

    PubMed Central

    Wielgosz, Joseph; Schuyler, Brianna S.; Lutz, Antoine; Davidson, Richard J.

    2016-01-01

    Respiration rate is known to correlate with aspects of psychological well-being, and attention to respiration is a central component of mindfulness meditation training. Both traditional contemplative systems and recent empirical evidence support an association between formal mindfulness practice and decreased respiration rate. However, the question of whether long-term mindfulness training is associated with stable, generalized changes in respiration has yet to be directly investigated. We analyzed respiration patterns across multiple time points, separated by two months or more, in a group of long-term mindfulness meditation practitioners (LTMs, n = 31) and a matched group of non-meditators (Controls, n = 38). On average, LTMs showed slower baseline respiration rate (RR) than Controls. Among LTMs, greater practice experience was associated with slower RR, independently of age and gender. Furthermore, this association was specific to intensive retreat practice, and was not seen for routine daily practice. Full days of meditation practice did not produce detectable changes in baseline RR, suggesting distal rather than immediate effects. All effects were independent of physiological characteristics including height, weight, body-mass index and waist-hip ratio. We discuss implications for continued study of the long-term effects of mindfulness training on health and well-being. PMID:27272738

  20. Long-term mindfulness training is associated with reliable differences in resting respiration rate.

    PubMed

    Wielgosz, Joseph; Schuyler, Brianna S; Lutz, Antoine; Davidson, Richard J

    2016-01-01

    Respiration rate is known to correlate with aspects of psychological well-being, and attention to respiration is a central component of mindfulness meditation training. Both traditional contemplative systems and recent empirical evidence support an association between formal mindfulness practice and decreased respiration rate. However, the question of whether long-term mindfulness training is associated with stable, generalized changes in respiration has yet to be directly investigated. We analyzed respiration patterns across multiple time points, separated by two months or more, in a group of long-term mindfulness meditation practitioners (LTMs, n = 31) and a matched group of non-meditators (Controls, n = 38). On average, LTMs showed slower baseline respiration rate (RR) than Controls. Among LTMs, greater practice experience was associated with slower RR, independently of age and gender. Furthermore, this association was specific to intensive retreat practice, and was not seen for routine daily practice. Full days of meditation practice did not produce detectable changes in baseline RR, suggesting distal rather than immediate effects. All effects were independent of physiological characteristics including height, weight, body-mass index and waist-hip ratio. We discuss implications for continued study of the long-term effects of mindfulness training on health and well-being. PMID:27272738

  1. Constraints on the affinity term for modeling long-term glass dissolution rates

    SciTech Connect

    Bourcier, W.L.; Carroll, S.A.; Phillips, B.L.

    1993-11-01

    Predictions of long-term glass dissolution rates are highly dependent on the form of the affinity term in the rate expression. Analysis of the quantitative effect of saturation state on glass dissolution rate for CSG glass (a simple analog of SRL-165 glass), shows that a simple (1-Q/K) affinity term does not match experimental results. Our data at 100{degree}C show that the data is better fit by an affinity term having the form (1 {minus} (Q/K){sup 1}/{sigma}) where {sigma} = 10.

  2. From Spark to Fire: Can Situational Reading Interest Lead to Long-Term Reading Motivation?

    ERIC Educational Resources Information Center

    Guthrie, John T.; Hoa, Laurel W.; Wigfield, Allan; Tonks, Stephen M.; Perencevich, Kathleen C.

    2006-01-01

    The processes of change in children's reading motivation have not been widely studied. We investigated whether situated interest for a specific book may lead to longer-term intrinsic motivation for general reading. Two schools with 120 grade 3 students filled out reading logs identifying their reasons for reading their favorite books twice. In…

  3. Quantifying present-day and long-term shale weathering rates across a latitudinal climosequence

    NASA Astrophysics Data System (ADS)

    Dere, A. L. D.; Andrews, E.; White, T. S.

    2015-12-01

    A transect of shale sites was established across the Northern Hemisphere as part of the Susquehanna Shale Hills Critical Zone Observatory (SSHO) to investigate the role of climate in shale weathering. Mean annual temperature and precipitation vary across sites located in Wales, New York, Pennsylvania, Virginia, Tennessee, Alabama and Puerto Rico. Long-term weathering rates were quantified by comparing bulk soil geochemistry with original parent shale composition and cosmogenic 10Be inventories to estimate weathering duration. Present-day weathering rates were obtained by burying approximately 2 cm by 1 cm shale chips at multiple depths in soil pit walls. Shale chip samples were exhumed after two and five years of burial, washed and mass loss measured. Scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS) were used to determine surface chemistry and physical alteration of the recovered shale. Long-term weathering rates increase with increasing temperature across the transect. Similarly, after two years of burial, exhumed shale chip weathering rates increased from 2.9 ± 0.9 in Wales to 11.2 ± 3.7 m Ma-1 in Puerto Rico. Average weathering rates after two years of burial were similar in Virginia, Tennessee and Alabama (8.6 - 10.6 m Ma-1). Many shale chips in Alabama and Puerto Rico, however, retained soil particles even after washing, therefore total mass loss, and thus weathering rates, at these sites could be even greater. After five years of burial, mass loss across the Appalachian sites was greatest in Tennessee while weathering rates were overall generally similar to two year rates (3.0 to 12.6 m Ma-1). Evidence of physical and chemical changes, especially Na and Mg loss, from shale chip surfaces was greater on shale chips buried at warmer and wetter sites. Quantifying weathering rates as a function of climate at multiple scales will contribute to understanding the effects of global climate change on soil formation rates in the Critical

  4. Effects of long-term grazing on sediment deposition and salt-marsh accretion rates

    NASA Astrophysics Data System (ADS)

    Elschot, Kelly; Bouma, Tjeerd J.; Temmerman, Stijn; Bakker, Jan P.

    2013-11-01

    Many studies have attempted to predict whether coastal marshes will be able to keep up with future acceleration of sea-level rise by estimating marsh accretion rates. However, there are few studies focussing on the long-term effects of herbivores on vegetation structure and subsequent effects on marsh accretion. Deposition of fine-grained, mineral sediment during tidal inundations, together with organic matter accumulation from the local vegetation, positively affects accretion rates of marsh surfaces. Tall vegetation can enhance sediment deposition by reducing current flow and wave action. Herbivores shorten vegetation height and this could potentially reduce sediment deposition. This study estimated the effects of herbivores on 1) vegetation height, 2) sediment deposition and 3) resulting marsh accretion after long-term (at least 16 years) herbivore exclusion of both small (i.e. hare and goose) and large grazers (i.e. cattle) for marshes of different ages. Our results firstly showed that both small and large herbivores can have a major impact on vegetation height. Secondly, grazing processes did not affect sediment deposition. Finally, trampling by large grazers affected marsh accretion rates by compacting the soil. In many European marshes, grazing is used as a tool in nature management as well as for agricultural purposes. Thus, we propose that soil compaction by large grazers should be taken in account when estimating the ability of coastal systems to cope with an accelerating sea-level rise.

  5. Long-term heart rate fluctuations in postoperative and brain-dead patients.

    PubMed

    Tamura, T; Maekawa, T; Nakajima, K; Sadamitsu, D; Tateishi, A

    1998-11-01

    Long-term heart rate fluctuations in postoperative and brain-dead patients were investigated. Heart rates were monitored continuously, and the data were stored, edited, and interpolated to allow for data lost during calibration and disconnection of the sensors for various treatments. Heart rate power spectra were calculated using the fast Fourier transform method. The power spectra of the patients who recovered showed that the heart rate fluctuated and produced a 1/f relationship, termed 1/f fluctuations, whereas those of patients who died in the intensive care unit (ICU) consisted of white-noise-like signals. The power spectra in brain-dead patients showed a 1/f relationship under steady-state conditions, while the power density and variation of the frequency distribution were lower than those in a normal subject. Therefore, 1/f fluctuations appear to be universal and occur independent of the central nervous system. PMID:9844751

  6. Natural selection fails to optimize mutation rates for long-term adaptation on rugged fitness landscapes.

    PubMed

    Clune, Jeff; Misevic, Dusan; Ofria, Charles; Lenski, Richard E; Elena, Santiago F; Sanjuán, Rafael

    2008-01-01

    The rate of mutation is central to evolution. Mutations are required for adaptation, yet most mutations with phenotypic effects are deleterious. As a consequence, the mutation rate that maximizes adaptation will be some intermediate value. Here, we used digital organisms to investigate the ability of natural selection to adjust and optimize mutation rates. We assessed the optimal mutation rate by empirically determining what mutation rate produced the highest rate of adaptation. Then, we allowed mutation rates to evolve, and we evaluated the proximity to the optimum. Although we chose conditions favorable for mutation rate optimization, the evolved rates were invariably far below the optimum across a wide range of experimental parameter settings. We hypothesized that the reason that mutation rates evolved to be suboptimal was the ruggedness of fitness landscapes. To test this hypothesis, we created a simplified landscape without any fitness valleys and found that, in such conditions, populations evolved near-optimal mutation rates. In contrast, when fitness valleys were added to this simple landscape, the ability of evolving populations to find the optimal mutation rate was lost. We conclude that rugged fitness landscapes can prevent the evolution of mutation rates that are optimal for long-term adaptation. This finding has important implications for applied evolutionary research in both biological and computational realms. PMID:18818724

  7. Natural Selection Fails to Optimize Mutation Rates for Long-Term Adaptation on Rugged Fitness Landscapes

    PubMed Central

    Clune, Jeff; Misevic, Dusan; Ofria, Charles; Lenski, Richard E.; Elena, Santiago F.; Sanjuán, Rafael

    2008-01-01

    The rate of mutation is central to evolution. Mutations are required for adaptation, yet most mutations with phenotypic effects are deleterious. As a consequence, the mutation rate that maximizes adaptation will be some intermediate value. Here, we used digital organisms to investigate the ability of natural selection to adjust and optimize mutation rates. We assessed the optimal mutation rate by empirically determining what mutation rate produced the highest rate of adaptation. Then, we allowed mutation rates to evolve, and we evaluated the proximity to the optimum. Although we chose conditions favorable for mutation rate optimization, the evolved rates were invariably far below the optimum across a wide range of experimental parameter settings. We hypothesized that the reason that mutation rates evolved to be suboptimal was the ruggedness of fitness landscapes. To test this hypothesis, we created a simplified landscape without any fitness valleys and found that, in such conditions, populations evolved near-optimal mutation rates. In contrast, when fitness valleys were added to this simple landscape, the ability of evolving populations to find the optimal mutation rate was lost. We conclude that rugged fitness landscapes can prevent the evolution of mutation rates that are optimal for long-term adaptation. This finding has important implications for applied evolutionary research in both biological and computational realms. PMID:18818724

  8. Reconciling Geodetic Deformation and Long-term Exhumation Rates Across the Western Greater Caucasus

    NASA Astrophysics Data System (ADS)

    Avdeev, B.; Niemi, N. A.

    2011-12-01

    Low modern geodetic strain rates and minimal instrumentally recorded seismicity in the western Greater Caucasus contradict the the high topography, deep exhumation, and young low-temperature thermochronometric ages indicative of active tectonic deformation in this mountain range. We use new and existing low-temperature thermochronometric data to show that the rate of present-day convergence across the range is sufficient to sustain observed rates of long-term exhumation and topographic growth. Thus, it is possible that the western Greater Caucasus has existed in an erosional steady state since shortly after the onset of exhumation of the range in Pliocene. We employ a Markov chain Monte Carlo algorithm to estimate the parameters of a thermokinematic model constrained by thermochronometric data and a focal mechanism solution from the 1991 Racha earthquake. We find that the thermochronometric data are best fit by exhumation commencing at ~4 Ma and driven by 3-5 mm/y of overthrusting on the Main Caucasus thrust dipping 40-45° at the surface and becoming flat at a depth of 15-20 km. This long-term exhumation model was compared with active rates of convergence in the western Greater Caucasus using an elastic half-space deformation model to estimate the geometry and rate of slip on a buried dislocation that best fits the observed geodetic velocity field. The estimated active slip of 4-7 mm/y is comparable to the long-term rate of overthrusting and is, therefore, sufficient to produce the observed rock uplift. Up to 4 mm/y excess of active convergence may potentially be consumed by underthrusting of the Transcaucasus or on faults south of the Main Caucasus thrust. We conclude that high rates of rock uplift observed in the western Greater Caucasus are the result of focused shortening occurring on a single fault. This differs from the deformation style of the eastern Greater Caucasus, where a larger amount of shortening is distributed across the width of the range with

  9. Interest rates mapping

    NASA Astrophysics Data System (ADS)

    Kanevski, M.; Maignan, M.; Pozdnoukhov, A.; Timonin, V.

    2008-06-01

    The present study deals with the analysis and mapping of Swiss franc interest rates. Interest rates depend on time and maturity, defining term structure of the interest rate curves (IRC). In the present study IRC are considered in a two-dimensional feature space-time and maturity. Exploratory data analysis includes a variety of tools widely used in econophysics and geostatistics. Geostatistical models and machine learning algorithms (multilayer perceptron and Support Vector Machines) were applied to produce interest rate maps. IR maps can be used for the visualisation and pattern perception purposes, to develop and to explore economical hypotheses, to produce dynamic asset-liability simulations and for financial risk assessments. The feasibility of an application of interest rates mapping approach for the IRC forecasting is considered as well.

  10. Predictors of Response Rates to a Long Term Follow-Up Mail out Survey

    PubMed Central

    Koloski, Natasha A.; Jones, Michael; Eslick, Guy; Talley, Nicholas J.

    2013-01-01

    Objective Very little is known about predictors of response rates to long-term follow-up mail-out surveys, including whether the timing of an incentive affects response rates. We aimed to determine whether the timing of the incentive affects response rates and what baseline demographic and psychological factors predict response rates to a 12 year follow-up survey. Study design and setting: Participants were 450 randomly selected people from the Penrith population, Australia who had previously participated in a mail-out survey 12 years earlier. By random allocation, 150 people received no incentive, 150 received a lottery ticket inducement with the follow-up survey and 150 received a lottery ticket inducement on the return of a completed survey. Results The overall response rate for the study was 63%. There were no significant differences in terms of response rates between the no incentive (58.8%;95%CI 49.8%,67.3%), incentive with survey (65.1%;95%CI 56.2%,73.3%) and promised incentive (65.3%;95%CI 56.1%,73.7%) groups. Independent predictors of responding to the 12 year survey were being older (OR=1.02, 95%CI 1.01,1.05,P=0.001) and being less neurotic as reported on the first survey 12 years earlier (OR=0.92, 95%CI 0.86,0.98, P=0.010). Conclusions Psychological factors may play a role in determining who responds to long-term follow-up surveys although timing of incentives does not. PMID:24223902

  11. Preliminary investigations of Spirulina effect on cancer cells: interest for long-term manned space missions

    NASA Astrophysics Data System (ADS)

    Baatout, S.; Bekaert, S.; Hendrickx, L.; Derradji, H.; Mergeay, M.

    Background In view of long haul space exploration missions the development of regenerative life support systems is of crucial importance to increase the crew autonomy and decrease the cost associated to the mass embarked Therefore in the late 80 s the European Space Agency initiated the MELiSSA project Micro-Ecological Life Support System Alternative MELiSSA has been conceived as a micro-organisms and higher plant process enabling high recycling efficiency The cyanobacteria Arthrospira sp is occupying one of the MELiSSA compartments Its genome is now being sequenced and this will help to better understand or improve its food value as well as to have a look at its putative toxic potential Aim In this study we were interested in studying the threshold of intrinsic cytotoxic effects of Spirulina dry extract from Sigma containing washed and lyophilized mixed Arthrospira strains on human cancer cells and its cell type dependency Method For that purpose we used flow cytometry to estimate cell death apoptosis and necrosis in three human leukaemic cell lines HELA cervix carcinoma IM-9 multiple myeloma K562 chronic myelogenous leukaemia Cells were cultured in the presence of an aqueous extract of Spirulina concentrations ranging from 0 to 500 mu g ml for 15 to 40 hours Apoptosis and necrosis were evaluated by annexin-V-PI staining cell size and granularity Early apoptosis was monitored by analysing the maintenance of mitochondrial membrane potential DioC 6 3 and the

  12. Metamemory ratings predict long-term changes in reactivated episodic memories

    PubMed Central

    Yacoby, Amnon; Dudai, Yadin; Mendelsohn, Avi

    2015-01-01

    Reactivation of long-term memory can render the memory item temporarily labile, offering an opportunity to modify it via behavioral or pharmacological intervention. Declarative memory reactivation is accompanied by a metamemory ability to subjectively assess the knowledge available concerning the target item (Feeling of knowing, FOK). We set out to examine whether FOK can predict the extent of change of long-term episodic memories by post-retrieval manipulations. To this end, participants watched a short movie and were immediately thereafter tested on their memory for it. A day later, they were reminded of that movie, and either immediately or 1 day later, were presented with a second movie. The reminder phase consisted of memory cues to which participants were asked to judge their FOK regarding the original movie. The memory performance of participants to whom new information was presented immediately after reactivating the original episode corresponded to the degree of FOK ratings upon reactivation such that the lower their FOK, the less their memory declined. In contrast, no relation was found between FOK and memory strength for those who learned new information 1 day after the reminder phase. Our findings suggest that the subjective accessibility of reactivated memories may determine the extent to which new information might modify those memories. PMID:25709571

  13. Effects of climate and mineral supply rates on long-term chemical weathering rates in granitic landscapes

    NASA Astrophysics Data System (ADS)

    Riebe, C. S.; Kirchner, J. W.; Finkel, R. C.

    2003-12-01

    We used cosmogenic nuclide and geochemical mass balance methods to measure long-term rates of chemical weathering and physical erosion of granitic terrain. Our 43 study sites encompass widely varying climates and denudation rates; mean annual temperatures vary from 2 to 32\\deg C, average annual precipitation spans a 20-fold range (from 22 to 420 cm/yr), and denudation rates vary by 32-fold across our sites. Long-term chemical weathering rates for these 43 sites range from 0 to 173 t km-2 yr-1, in several cases exceeding the highest granitic weathering rates on record from previous work. Chemical weathering rates are highest at sites with rapid denudation rates, consistent with strong coupling between rates of chemical weathering and mineral supply from physical erosion of rock. To account for effects of mineral supply in analyzing how climate affects chemical weathering, we introduce the "Weathering Intensity Factor" (WIF), the ratio of chemical weathering rate to physical erosion rate. WIF's increase systematically with average annual precipitation and mean annual temperature, both for the soil as a whole, and for individual component elements including Si, Na, and Ca. Between 59 and 79 percent of the variance in WIF's can be explained by a simple Arrhenius-like relationship based on mean annual temperature and average annual precipitation. Moreover, when we couple this Arrhenius relationship with our measurements of long-term erosion rates, we obtain a simple prediction equation that explains between 79 and 93 percent of the variance in long-term chemical weathering rates. The temperature-dependence of WIF is roughly half what one would expect from laboratory measurements of activation energies for feldspar weathering. Our results imply that the strength of climate change feedbacks between temperature and silicate weathering rates may be weaker than previously thought, at least in actively eroding, unglaciated terrain similar to our study sites. Our results

  14. Long-term Evolution of Seismicity Rates in California Geothermal Fields

    NASA Astrophysics Data System (ADS)

    Trugman, D. T.; Shearer, P. M.; Borsa, A. A.; Fialko, Y. A.

    2015-12-01

    The temporal evolution of seismicity rates within geothermal fields provides important observational constraints on the ways in which rocks respond to natural and anthropogenic loading. We develop an iterative, regularized inversion procedure to partition the observed seismicity rate into two primary components: (1) the interaction seismicity rate due to earthquake-earthquake triggering, and (2) the time-varying background seismicity rate controlled by other time-dependent stresses, including anthropogenic forcing. We parameterize our seismicity model using an Epidemic-Type Aftershock Sequence (ETAS) framework with a background seismicity rate that varies smoothly with time. We apply our methodology to study long-term changes in seismicity rates at the Geysers and Salton Sea geothermal fields in California. At the Geysers, we find that the background seismicity rate is highly correlated with fluid injection. Seismicity at the Geysers has experienced a rate increase of approximately 50% since year 2000 and exhibits strong seasonal fluctuations, both of which can be explained by changes in fluid injection following the completion of the Santa Rosa pipeline. At the Salton Sea, the background seismicity rate has remained relatively stable since 1990, with short-term fluctuations that are not obviously modulated by fluid fluxes related to the operation of the geothermal field. The differences in the field-wide seismicity responses of the Geysers and Salton Sea to geothermal plant operation may reflect differences in in-situ reservoir conditions and local tectonics, indicating that induced seismicity may not be solely a function of fluid injection and withdrawal.

  15. Do erosion rates control the long-term carbon isotope mass balance?

    NASA Astrophysics Data System (ADS)

    Shields-Zhou, G. A.

    2014-12-01

    The long-term marine carbon isotope record responds to changes in the proportional burial rates of organic carbon relative to carbonate carbon on a global scale. For this reason, high δ13C values in marine carbonate rocks are normally interpreted to reflect faster rates of organic burial and increased atmospheric oxygenation. Geochemical redox tracers fail to support this paradigm for sustained deviations from the long-term δ13C mean, indicating perhaps that proportionally high organic burial may be associated with lower overall flux rates. Here I propose that ~107-108 year trends in average δ13C, as with seawater 87Sr/86Sr, are driven by changes in the balance between volcanism and denudation (~uplift). In other words, high proportional organic burial may be related to increases in the net CO2 flux (= organic carbon burial + Ca-Mg silicate weathering) relative to the carbonate weathering flux. According to this model, high baseline δ13C values will be associated with periods of heightened volcanic activity and/or diminished tectonic uplift. Conversely, lower baseline δ13C values can be related to times when the global carbon cycle was dominated by carbonate and oxidative weathering due to high rates of physical erosion. Shorter 105-106 year positive δ13C excursions have also been interpreted as the 'smoking gun' to extreme oxygenation events. However, large increases in organic burial are difficult to sustain under steady-state conditions without very high volcanic fluxes, indicating that some of these excursions might be better explained by transient changes to the isotopic composition of carbon sources and sinks.

  16. Revised long-term creep rates on the Hayward Fault, Alameda and Contra Costa Counties, California

    USGS Publications Warehouse

    Lienkaemper, James J.; Galehouse, Jon S.

    1997-01-01

    Although the Hayward fault is a source of major earthquakes, it also creeps or slips aseismically, and has done so steadily for several decades (certainly since 1921 and probably since 1869). Most of the fault creeps between 3 and 6 mm/yr, except for a 4- to 6-km-long segment near its south end that creeps at about 9 mm/yr. We present results of our recent surveys to recover angles and deflection lines established across the fault in the 1960s and 1970s, but unmonitored since. We have added data from more offset cultural features to the long-term creep rate data set and made substantial improvements to the analytical method used to compute offsets. The revised creep rate values improve our knowledge of spatial and temporal variation along the fault. The more accurate revised data has reduced the estimate of the average creep rate along most of the fault from 5.1 mm/yr to 4.6 mm/yr. Creep rates in the 9 mm/yr section near the south end have remained the same.

  17. Discrimination power of long-term heart rate variability measures for chronic heart failure detection.

    PubMed

    Melillo, Paolo; Fusco, Roberta; Sansone, Mario; Bracale, Marcello; Pecchia, Leandro

    2011-01-01

    The aim of this study was to investigate the discrimination power of standard long-term heart rate variability (HRV) measures for the diagnosis of chronic heart failure (CHF). The authors performed a retrospective analysis on four public Holter databases, analyzing the data of 72 normal subjects and 44 patients suffering from CHF. To assess the discrimination power of HRV measures, an exhaustive search of all possible combinations of HRV measures was adopted and classifiers based on Classification and Regression Tree (CART) method was developed, which is a non-parametric statistical technique. It was found that the best combination of features is: Total spectral power of all NN intervals up to 0.4 Hz (TOTPWR), square root of the mean of the sum of the squares of differences between adjacent NN intervals (RMSSD) and standard deviation of the averages of NN intervals in all 5-min segments of a 24-h recording (SDANN). The classifiers based on this combination achieved a specificity rate and a sensitivity rate of 100.00 and 89.74%, respectively. The results are comparable with other similar studies, but the method used is particularly valuable because it provides an easy to understand description of classification procedures, in terms of intelligible "if … then …" rules. Finally, the rules obtained by CART are consistent with previous clinical studies. PMID:21203855

  18. Long-term recurrence and complication rates after incisional hernia repair with the open onlay technique

    PubMed Central

    Andersen, Lars Peter Holst; Klein, Mads; Gögenur, Ismail; Rosenberg, Jacob

    2009-01-01

    Background Incisional hernia after abdominal surgery is a well-known complication. Controversy still exists with respect to the choice of hernia repair technique. The objective of this study was to evaluate the long-term recurrence rate as well as surgical complications in a consecutive group of patients undergoing open repair using an onlay mesh technique. Methods Consecutive patients undergoing open incisional hernia repair with onlay-technique between 01/05/1995 and 01/09/2007 at a single institution were included in the study. For follow-up patients were contacted by telephone, and answered a questionnaire containing questions related to the primary operation, the hernia and general risk factors. Patients were examined by a consultant surgeon in the outpatient clinic or in the patient's home if there was suspicion of an incisional hernia recurrence. Results The study included 56 patients with 100% follow-up. The median follow-up was 35 months (range 4–151). Recurrent incisional hernia was found in 8 of 56 patients (15%, 95% CI: 6–24). The overall complication rate was 13% (95% CI, 4–22). All complications were minor and needed no hospital admission. Conclusion This study with a long follow-up showed low recurrence and complication rates in patients undergoing incisional hernia repair with the open onlay technique. PMID:19400934

  19. Daily and Long Term Variations of Out-Door Gamma Dose Rate in Khorasan Province, Iran

    SciTech Connect

    Toossi, M. T. Bahreyni; Bayani, SH.

    2008-08-07

    In Iran before 1996, only a few hot spots had been identified, no systematic study had been envisaged. Since then preparation of out-door environmental gamma radiation map of Iran was defined as a long term goal in our center, at the same time simultaneous monitoring of outdoor gamma level in Khorasan was also proposed. A Rados area monitoring system (AAM-90) including 10 intelligent RD-02 detector and all associated components were purchased. From 2003 gradually seven stations have been setup in Khorasan. For all seven stations monthly average and one hour daily average on four time intervals have been computed. Statistically no significant differences have been observed. This is also true for monthly averages. The overall average dose rate for present seven stations varies from 0.11 {mu}Sv{center_dot}h{sup -1} for Ferdows, to 0.04 {mu}Sv{center_dot}h{sup -1} for Dargaz. Based on our data, 50 minutes sample in any time interval is an accurate sample size to estimate out door Gamma dose rate.

  20. Effect of Long-term Smoking on Whole-mouth Salivary Flow Rate and Oral Health

    PubMed Central

    Rad, Maryam; Kakoie, Shahla; Niliye Brojeni, Fateme; Pourdamghan, Nasim

    2010-01-01

    Background and aims Change in the resting whole-mouth salivary flow rate (SFR) plays a significant role in patho-genesis of various oral conditions. Factors such as smoking may affect SFR as well as the oral and dental health. The primary purpose of this study was to determine the effect of smoking on SFR, and oral and dental health. Materials and methods One-hundred smokers and 100 non-tobacco users were selected as case and control groups, respectively. A questionnaire was used to collect the demographic data and smoking habits. A previously used questionnaire about dry mouth was also employed. Then, after a careful oral examination, subjects’ whole saliva was collected in the resting condition. Data was analyzed by chi-square test using SPSS 15. Results The mean (±SD) salivary flow rate were 0.38 (± 0.13) ml/min in smokers and 0.56 (± 0.16) ml/min in non-smokers. The difference was statistically significant (P=0.00001). Also, 39% of smokers and 12% of non-smokers reported experiencing at least one xerostomia symptom, with statistically significant difference between groups (p=0.0001). Oral lesions including cervical caries, gingivitis, tooth mobility, calculus and halitosis were significantly higher in smokers. Conclusion Our findings indicated that long-term smoking would significantly reduce SFR and increase oral and dental disorders associated with dry mouth, especially cervical caries, gingivitis, tooth mobility, calculus, and halitosis. PMID:23346336

  1. Long-Term Recurrence Rates of Peptic Ulcers without Helicobacter pylori

    PubMed Central

    Seo, Jae Hyun; Hong, Su Jin; Kim, Jie-Hyun; Kim, Byung-Wook; Jee, Sam Ryong; Chung, Woo Chul; Shim, Ki-Nam; Baik, Gwang Ho; Kim, Sung Soo; Kim, Sang Gyun; Kim, Jin Il

    2016-01-01

    Background/Aims The purpose of this study is to investigate the recurrence rate of peptic ulcer disease (PUD) over a long follow-up period with PUD patients without Helicobacter pylori. Methods We retrospectively reviewed patients diagnosed with PUD on endoscopy and divided them into two groups: a H. pylori-negative group (HP-negative group), and a group of patients with untreated H. pylori (HP noneradicated group). We compared the recurrence rates of PUD in these two groups and analyzed the factors that affected ulcer recurrence. Results Total of nine hospitals in Korea participated, and a total of 1,761 patients were retrospectively reviewed. The HP-negative group included 553 patients, and the HP noneradicated group included 372 patients. The 5-year cumulative probabilities of PUD recurrence were 36.4% in the HP-negative group and 43.8% in the HP noneradicated group (p=0.113). The factors that were found to affect recurrence in the HP-negative group were elder, male, and comorbid chronic kidney disease. Conclusions The 5-year cumulative probability of PUD recurrence without H. pylori infection after a long-term follow-up was 36.4% and the factors that affected recurrence were elder, male, and comorbid chronic kidney disease. PMID:27114412

  2. Changes in cat medullary neurone firing rates and synchrony following induction of respiratory long-term facilitation

    PubMed Central

    Morris, K F; Shannon, R; Lindsey, B G

    2001-01-01

    Long-term facilitation is a respiratory memory expressed as an increase in motor output lasting more than an hour. This change is induced by repeated hypoxia, stimulation of carotid chemoreceptors, or electrical stimulation of the carotid sinus nerve or brainstem mid-line. The present work addressed the hypothesis that persistent changes in medullary respiratory neural networks contribute to long-term facilitation. Carotid chemoreceptors were stimulated by close arterial injection of CO2-saturated saline solution. Phrenic nerve efferent activity and up to 30 single medullary neurones were recorded simultaneously in nucleus tractus solitarii (NTS) including the dorsal respiratory group (DRG), Bötzinger-ventral respiratory group (Böt-VRG), and nucleus raphe obscurus of nine adult cats, anaesthetized, injected with a neuromuscular blocking agent, vagotomized and artificially ventilated. The firing rates of 87 of 105 neurones (83 %) changed following induction of long-term facilitation. Nine of eleven DRG and Böt-VRG putative premotor inspiratory neurones had increased firing rates with long-term facilitation. Fourteen of twenty-one raphe obscurus neurones with control firing rates less than 4 Hz had significant long-term increases in activity. Cross-correlogram analysis suggested that there were changes in effective connectivity of neuron pairs with long-term facilitation. Joint peristimulus time histograms and pattern detection methods used with ‘gravity’ analysis also detected changes in short time scale correlations associated with long-term facilitation. The results suggest that changes in firing rates and synchrony of VRG and DRG premotor neurones and altered effective connectivity among other functionally antecedent elements of the medullary respiratory network contribute to the expression of long-term facilitation. PMID:11306666

  3. Readmission Rates and Long-Term Hospital Costs Among Survivors of In-Hospital Cardiac Arrest

    PubMed Central

    Chan, Paul S.; Nallamothu, Brahmajee K.; Krumholz, Harlan M.; Curtis, Lesley H.; Li, Yan; Hammill, Bradley G.; Spertus, John A.

    2014-01-01

    Background Although in-hospital cardiac arrest is common, little is known about readmission patterns and inpatient resource use among survivors of in-hospital cardiac arrest. Methods and Results Within a large national registry, we examined long-term inpatient utilization among 6972 adults ≥65 years who survived an in-hospital cardiac arrest. We examined 30-day and 1-year readmission rates and inpatient costs, overall and by patient demographics, hospital disposition (discharge destination), and neurological status at discharge. The mean age was 75.8 ± 7.0 years, 56% were men, and 12% were black. There were a total of 2005 readmissions during the first 30 days (cumulative incidence rate: 35 readmissions/100 patients [95% CI: 33–37]) and 8751 readmissions at 1 year (cumulative incidence rate: 185 readmissions/100 patients [95% CI: 177–190]). Overall, mean inpatient costs were $7,741 ± $2323 at 30 days and $18,629 ± $9411 at 1 year. Thirty-day inpatient costs were higher in patients of younger age (≥85 years: $6052 [reference]; 75–84 years: $7444 [adjusted cost ratio, 1.23 [1.06–1.42]; 65–74 years: $8291 [adjusted cost ratio, 1.37 [1.19–1.59]; both P<0.001]) and black race (whites: $7413; blacks: $9044; adjusted cost ratio, 1.22 [1.05–1.42]; P<0.001), as well as those discharged with severe neurological disability or to skilled nursing or rehabilitation facilities. These differences in resource use persisted at 1 year and were largely due to higher readmission rates. Conclusion Survivors of in-hospital cardiac arrest have frequent readmissions and high follow-up inpatient costs. Readmissions and inpatient costs were higher in certain subgroups, including patients of younger age and black race. PMID:25351479

  4. Extremely low long-term erosion rates around the Gamburtsev Mountains in interior East Antarctica

    NASA Astrophysics Data System (ADS)

    Cox, S. E.; Thomson, S. N.; Reiners, P. W.; Hemming, S. R.; van de Flierdt, T.

    2010-11-01

    The high elevation and rugged relief (>3 km) of the Gamburtsev Subglacial Mountains (GSM) have long been considered enigmatic. Orogenesis normally occurs near plate boundaries, not cratonic interiors, and large-scale tectonic activity last occurred in East Antarctica during the Pan-African (480-600 Ma). We sampled detrital apatite from Eocene sands in Prydz Bay at the terminus of the Lambert Graben, which drained a large pre-glacial basin including the northern Gamburtsev Mountains. Apatite fission-track and (U-Th)/He cooling ages constrain bedrock erosion rates throughout the catchment. We double-dated apatites to resolve individual cooling histories. Erosion was very slow, averaging 0.01-0.02 km/Myr for >250 Myr, supporting the preservation of high elevation in interior East Antarctica since at least the cessation of Permian rifting. Long-term topographic preservation lends credence to postulated high-elevation mountain ice caps in East Antarctica since at least the Cretaceous and to the idea that cold-based glaciation can preserve tectonically inactive topography.

  5. Coupling of realistic rate estimates with genomic for Assessing Contaminant Attenuation and Long-Term Phone

    SciTech Connect

    Colwell, F. S.; Crawford, R. L.; Sorenson, K.

    2003-06-01

    Dissolved dense nonaqueous-phase liquid plumes are persistent, widespread problems in the DOE complex. While perceived as being difficult to degrade, at the Idaho National Engineering and Environmental Laboratory, dissolved trichloroethylene (TCE) is disappearing from the Snake River Plain aquifer (SRPA) by natural attenuation, a finding that saves significant site restoration costs. Acceptance of monitored natural attenuation as a preferred treatment technology requires direct proof of the process and rate of the degradation. Our proposal aims to provide that proof for one such site by testing two hypotheses. First, we believe that realistic values for in situ rates of TCE cometabolism can be obtained by sustaining the putative microorganisms at the low catabolic activities consistent with aquifer conditions. Second, the patterns of functional gene expression evident in these communities under starvation conditions while carrying out TCE cometabolism can be used to diagnose the cometabolic activity in the aquifer itself. Using the cometabolism rate parameters derived in low-growth bioreactors, we will complete the models that predict the time until background levels of TCE are attained at this location and validate the long term stewardship of this plume. Realistic terms for cometabolism of TCE will provide marked improvements in DOE's ability to predict and monitor natural attenuation of chlorinated organics at other sites, increase the acceptability of this solution, and provide significant economic and health benefits through this noninvasive remediation strategy. Finally, this project will derive valuable genomic information about the functional attributes of subsurface microbial communities upon which DOE must depend to resolve some of its most difficult contamination issues.

  6. A long-term rock uplift rate for eastern Crete from exposure dating of marine terraces

    NASA Astrophysics Data System (ADS)

    Strobl, M.; Hetzel, R.; Ivy-Ochs, S.; Alfimov, V.; Kubik, P. W.; Fassoulas, C.; Palumbo, L.

    2009-04-01

    The island of Crete in the forearc of the Hellenic subduction zone has a rugged topography with a relief exceeding 2 km. Rock uplift rates of 2-4 mm/a were estimated previously from raised Late Holocene shorelines (Lambeck, 1995) but may not be representative on longer timescales, because earthquakes with up to 9 m of coseismic uplift have recently affected Crete (Stiros, 2001). Here we use marine terraces near Kato Zakros to quantify the long-term rock uplift rate for eastern Crete. Our field investigations and topographic profiles document a flight of at least 15 marine bedrock terraces carved into limestone bedrock. Age constraints for the terraces were obtained by 36Cl exposure dating of bedrock samples and 10Be dating of sandstone cobbles found on some terraces. Our results suggest that the terraces T4 and T5 at elevations of 68 and 76 m, respectively, formed during sea level highstands associated with marine isotope stage 5e, i.e. ~125 ka ago. Correlating the other terraces (T1 to T11) to a sea-level curve for the Red Sea (Siddall et al., 2003) indicates an uplift rate of 0.5-0.6 mm/a during the last 400 ka; significantly lower than previous estimates based on the elevation of Late Holocene shorelines. References Lambeck, K. (1995), Late Pleistocene and Holocene sea-level change in Greece and SW Turkey - a separation of eustatic, isostatic and tectonic contributions. Geophys. J. Int. 122, 1022-1044. Siddall, M., Rohling, E.J., Almogi-Labin, A., Hemleben, C., Meischner, D., Schmelzer, I., and Smeed, D.A. (2003), Sea-level fluctuations during the last glacial cycle. Nature, 423, 853-858. Stiros, S.C. (2001), The AD 365 Crete earthquake and possible seismic clustering during the fourth to sixth centuries AD in the Eastern Mediterranean: a review of historical and archaeological data. J. Struct. Geol., 23, 545-562.

  7. Long-term dynamics of death rates of emphysema, asthma, and pneumonia and improving air quality

    PubMed Central

    Kravchenko, Julia; Akushevich, Igor; Abernethy, Amy P; Holman, Sheila; Ross, William G; Lyerly, H Kim

    2014-01-01

    Background The respiratory tract is a major target of exposure to air pollutants, and respiratory diseases are associated with both short- and long-term exposures. We hypothesized that improved air quality in North Carolina was associated with reduced rates of death from respiratory diseases in local populations. Materials and methods We analyzed the trends of emphysema, asthma, and pneumonia mortality and changes of the levels of ozone, sulfur dioxide (SO2), nitrogen dioxide (NO2), carbon monoxide (CO), and particulate matters (PM2.5 and PM10) using monthly data measurements from air-monitoring stations in North Carolina in 1993–2010. The log-linear model was used to evaluate associations between air-pollutant levels and age-adjusted death rates (per 100,000 of population) calculated for 5-year age-groups and for standard 2000 North Carolina population. The studied associations were adjusted by age group-specific smoking prevalence and seasonal fluctuations of disease-specific respiratory deaths. Results Decline in emphysema deaths was associated with decreasing levels of SO2 and CO in the air, decline in asthma deaths–with lower SO2, CO, and PM10 levels, and decline in pneumonia deaths–with lower levels of SO2. Sensitivity analyses were performed to study potential effects of the change from International Classification of Diseases (ICD)-9 to ICD-10 codes, the effects of air pollutants on mortality during summer and winter, the impact of approach when only the underlying causes of deaths were used, and when mortality and air-quality data were analyzed on the county level. In each case, the results of sensitivity analyses demonstrated stability. The importance of analysis of pneumonia as an underlying cause of death was also highlighted. Conclusion Significant associations were observed between decreasing death rates of emphysema, asthma, and pneumonia and decreases in levels of ambient air pollutants in North Carolina. PMID:25018627

  8. Jensen's Inequality and the Impact of Short-Term Environmental Variability on Long-Term Population Growth Rates.

    PubMed

    Pickett, Evan J; Thomson, David L; Li, Teng A; Xing, Shuang

    2015-01-01

    It is well established in theory that short-term environmental fluctuations could affect the long-term growth rates of wildlife populations, but this theory has rarely been tested and there remains little empirical evidence that the effect is actually important in practice. Here we develop models to quantify the effects of daily, seasonal, and yearly temperature fluctuations on the average population growth rates, and we apply them to long-term data on the endangered Black-faced Spoonbill (Platalea minor); an endothermic species whose population growth rates follow a concave relationship with temperature. We demonstrate for the first time that the current levels of temperature variability, particularly seasonal variability, are already large enough to substantially reduce long-term population growth rates. As the climate changes, our results highlight the importance of considering the ecological effects of climate variability and not just average conditions. PMID:26352857

  9. Timing and rates of long-term landscape evolution in Southern Argentina

    NASA Astrophysics Data System (ADS)

    Kollenz, S.; Glasmacher, P. A.

    2013-12-01

    The eastern Argentina South Atlantic passive continental margin is distinguished by a very flat topography. Out of the so called Pampean flat two mountain ranges are arising. These mountain ranges, the Sierras Australes and the Sierras Septentrionales, are located in the State of Buenos Aires south of the capital Buenos Aires. North of the Sierras Septentrionales the Salado basin is located. The Sierras Septentrionales and the Sierras Australes are also divided by a smaller intracratonic basin. Further in the South the Colorado basin is located. The Sierras Australes is a variscian fold belt originated by strong phases of metamorphosis, but till now it is unclear by how many tectonic phases the area was influenced (Tomezzoli & Vilas, 1999). It consists of Proterozoic to Paleozoic rocks. The Sierras Septentrionales consists mainly of Precambrian crystalline rocks. The Precambrian sequences are overlain by younger Sediments (Cingolani, 2010). The aim is to understand the long-term landscape evolution of the area by quantifiying erosion- and exhumation-rates and by dating ancient rock-uplift-events. Another goal is to find out how the opening of the south atlantic took effect on this region. To fulfill this goal, thermochronological techniques, such as fission-track dating and (U-Th-Sm)/He dating has been applied to samples from the region. Because there was no low- temperature thermochronology done in this area, both techniques were applied on apatites and zircons. Furthermore, numerical modeling of the cooling history has provided the data base for the quantification of the exhumation rates. The data-set shows clusters of different ages which can be linked to tectonic activities during late Paleozoic times. Also the thermokinematic modeling is leading to new insights of the evolution of both mountain ranges and shows patterns of ongoing tectonic processes in this region. Caltculated exhumation rates show also varying cooling historys and the influence of tectonics

  10. Timing and rates of long-term landscape evolution in Southern Argentina

    NASA Astrophysics Data System (ADS)

    Kollenz, Sebastian; Glasmacher, Ulrich A.; Rossello, Eduardo A.; Stoeckli, Danny F.

    2014-05-01

    The eastern Argentina South Atlantic passive continental margin is distinguished by a very flat topography. Out of the so called Pampean flat two mountain ranges are arising. These mountain ranges, the Sierras Australes and the Sierras Septentrionales, are located in the State of Buenos Aires south of the capital Buenos Aires. North of the Sierras Septentrionales the Salado basin is located. The Sierras Septentrionales and the Sierras Australes are also divided by a smaller intracratonic basin. Further in the South the Colorado basin is located. The Sierras Australes is a variscian fold belt originated by strong phases of metamorphosis, but till now it is unclear by how many tectonic phases the area was influenced (Tomezzoli & Vilas, 1999). It consists of Proterozoic to Paleozoic rocks. The Sierras Septentrionales consists mainly of Precambrian crystalline rocks. The Precambrian sequences are overlain by younger Sediments (Cingolani, 2010). The aim is to understand the long-term landscape evolution of the area by quantifiying erosion- and exhumation-rates and by dating ancient rock-uplift-events. Another goal is to find out how the opening of the south atlantic took effect on this region. To fulfill this goal, thermochronological techniques, such as fission-track dating and (U-Th-Sm)/He dating has been applied to samples from the region. Because there was no low- temperature thermochronology done in this area, both techniques were applied on apatites and zircons. Furthermore, numerical modeling of the cooling history has provided the data base for the quantification of the exhumation rates. The data-set show clusters of different ages which can be linked to tectonic activities during late Paleozoic times. Also the thermokinematic modeling is leading to new insights of the evolution of both mountain ranges and shows patterns of ongoing tectonic processes in this region. Calculated exhumation rates show also varying cooling histories and the influence of tectonics

  11. Long-term analysis of survival, fertility, and population growth rate of black bears in North Carolina

    USGS Publications Warehouse

    Brongo, L.L.; Mitchell, M.S.; Grand, J.B.

    2005-01-01

    We estimated survival, fertility, and realized and asymptotic population growth rates from 1981 to 2002 for a protected population of black bears (Ursus americanus) in the southern Appalachian Mountains. We used Akaike's information criterion to assess the time interval for averaging observations that was best for estimating vital rates for our study, given our yearly sample sizes. The temporal symmetry approach allowed us to directly assess population growth and to address all losses and gains to the population by using only capture data, offering an alternative to the logistically intensive collection of reproductive data. Models that averaged survival and fertility across 5- and 7-year time intervals were best supported by our data. Studies of black bear populations with annual sample sizes similar to ours should be of at least 5 years in duration to estimate vital rates reliably, and at least 10 years in duration to evaluate changes in population growth rate (??). We also hypothesized that survival would not track changes in ?? because ?? is influenced by both survival and fertility. The 5-year model supported our hypothesis, but the 7-year model did not. Where long-term dynamics of large, relatively stable bear populations are of interest, monitoring survival is likely to be sufficient for evaluating trends in ??. For rapidly changing, small populations, however, failure to incorporate fertility into assessments of ?? could be misleading. ?? 2005 American Society of Mammalogists.

  12. Simulating long-term effects of nitrogen fertilizer application rates on corn yield and nitrogen dynamics

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Thoroughly tested agricultural systems models can be used to quantify the long-term effects of crop management practices under conditions where measurements are lacking. In a field near Story City, Iowa, ten years (1996-2005) of measured data were collected from plots receiving low, medium, and high...

  13. Electronic Medical Record and Quality Ratings of Long Term Care Facilities Long-Term Care Facility Characteristics and Reasons and Barriers for Adoption of Electronic Medical Record

    ERIC Educational Resources Information Center

    Daniels, Cheryl Andrea

    2013-01-01

    With the growing elderly population, compounded by the retirement of the babyboomers, the need for long-term care (LTC) facilities is expected to grow. An area of great concern for those that are seeking a home for their family member is the quality of care provided by the nursing home to the residents. Electronic medical records (EMR) are often…

  14. 41 CFR 301-11.14 - How is my daily lodging rate computed when I rent lodging on a long-term basis?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... rate computed when I rent lodging on a long-term basis? 301-11.14 Section 301-11.14 Public Contracts... computed when I rent lodging on a long-term basis? When you obtain lodging on a long-term basis (e.g., weekly or monthly) your daily lodging rate is computed by dividing the total lodging cost by the...

  15. 41 CFR 301-11.14 - How is my daily lodging rate computed when I rent lodging on a long-term basis?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... rate computed when I rent lodging on a long-term basis? 301-11.14 Section 301-11.14 Public Contracts... computed when I rent lodging on a long-term basis? When you obtain lodging on a long-term basis (e.g., weekly or monthly) your daily lodging rate is computed by dividing the total lodging cost by the...

  16. 41 CFR 301-11.14 - How is my daily lodging rate computed when I rent lodging on a long-term basis?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... rate computed when I rent lodging on a long-term basis? 301-11.14 Section 301-11.14 Public Contracts... computed when I rent lodging on a long-term basis? When you obtain lodging on a long-term basis (e.g., weekly or monthly) your daily lodging rate is computed by dividing the total lodging cost by the...

  17. 41 CFR 301-11.14 - How is my daily lodging rate computed when I rent lodging on a long-term basis?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... rate computed when I rent lodging on a long-term basis? 301-11.14 Section 301-11.14 Public Contracts... computed when I rent lodging on a long-term basis? When you obtain lodging on a long-term basis (e.g., weekly or monthly) your daily lodging rate is computed by dividing the total lodging cost by the...

  18. Short-term vs. long-term heart rate variability in ischemic cardiomyopathy risk stratification

    PubMed Central

    Voss, Andreas; Schroeder, Rico; Vallverdú, Montserrat; Schulz, Steffen; Cygankiewicz, Iwona; Vázquez, Rafael; Bayés de Luna, Antoni; Caminal, Pere

    2013-01-01

    In industrialized countries with aging populations, heart failure affects 0.3–2% of the general population. The investigation of 24 h-ECG recordings revealed the potential of nonlinear indices of heart rate variability (HRV) for enhanced risk stratification in patients with ischemic heart failure (IHF). However, long-term analyses are time-consuming, expensive, and delay the initial diagnosis. The objective of this study was to investigate whether 30 min short-term HRV analysis is sufficient for comparable risk stratification in IHF in comparison to 24 h-HRV analysis. From 256 IHF patients [221 at low risk (IHFLR) and 35 at high risk (IHFHR)] (a) 24 h beat-to-beat time series (b) the first 30 min segment (c) the 30 min most stationary day segment and (d) the 30 min most stationary night segment were investigated. We calculated linear (time and frequency domain) and nonlinear HRV analysis indices. Optimal parameter sets for risk stratification in IHF were determined for 24 h and for each 30 min segment by applying discriminant analysis on significant clinical and non-clinical indices. Long- and short-term HRV indices from frequency domain and particularly from nonlinear dynamics revealed high univariate significances (p < 0.01) discriminating between IHFLR and IHFHR. For multivariate risk stratification, optimal mixed parameter sets consisting of 5 indices (clinical and nonlinear) achieved 80.4% AUC (area under the curve of receiver operating characteristics) from 24 h HRV analysis, 84.3% AUC from first 30 min, 82.2 % AUC from daytime 30 min and 81.7% AUC from nighttime 30 min. The optimal parameter set obtained from the first 30 min showed nearly the same classification power when compared to the optimal 24 h-parameter set. As results from stationary daytime and nighttime, 30 min segments indicate that short-term analyses of 30 min may provide at least a comparable risk stratification power in IHF in comparison to a 24 h analysis period. PMID:24379785

  19. Early and long-term mantle processing rates derived from xenon isotopes

    NASA Astrophysics Data System (ADS)

    Mukhopadhyay, S.; Parai, R.; Tucker, J.; Middleton, J. L.; Langmuir, C. H.

    2015-12-01

    Noble gases, particularly xenon (Xe), in mantle-derived basalts provide a rich portrait of mantle degassing and surface-interior volatile exchange. The combination of extinct and extant radioactive species in the I-Pu-U-Xe systems shed light on the degassing history of the early Earth throughout accretion, as well as the long-term degassing of the Earth's interior in association with plate tectonics. The ubiquitous presence of shallow-level air contamination, however, frequently obscures the mantle Xe signal. In a majority of the samples, shallow air contamination dominates the Xe budget. For example, in the gas-rich popping rock 2ΠD43, 129Xe/130Xe ratios reach 7.7±0.23 in individual step-crushes, but the bulk composition of the sample is close to air (129Xe/130Xe of 6.7). Thus, the extent of variability in mantle source Xe composition is not well-constrained. Here, we present new MORB Xe data and explore constraints placed on mantle processing rates by the Xe data. Ten step-crushes were obtained on a depleted popping glass that was sealed in ultrapure N2 after dredge retrieval from between the Kane-Atlantis Fracture Zone of the Mid Atlantic Ridge in May 2012. 9 steps yielded 129Xe/130Xe of 7.50-7.67 and one yielded 7.3. The bulk 129Xe/130Xe of the sample is 7.6, nearly identical to the estimated mantle source value of 7.7 for the sample. Hence, the sample is virtually free of shallow-level air contamination. Because sealing the sample in N2upon dredge retrieval largely eliminated air contamination, for many samples, contamination must be added after sample retrieval from the ocean bottom. Our new high-precision Xe isotopic measurements in upper mantle-derived samples provide improved constraints on the Xe isotopic composition of the mantle source. We developed a forward model of mantle volatile evolution to identify solutions that satisfy our Xe isotopic data. We find that accretion timescales of ~10±5 Myr are consistent with I-Pu-Xe constraints, and the last

  20. Points of Interest: What Determines Interest Rates?

    ERIC Educational Resources Information Center

    Schilling, Tim

    Interest rates can significantly influence people's behavior. When rates decline, homeowners rush to buy new homes and refinance old mortgages; automobile buyers scramble to buy new cars; the stock market soars, and people tend to feel more optimistic about the future. But even though individuals respond to changes in rates, they may not fully…

  1. LONG-TERM EFFECTS OF LAND APPLICATION OF DOMESTIC WASTEWATER, ROSWELL, NEW MEXICO, SLOW RATE IRRIGATION SITE

    EPA Science Inventory

    This report presents the findings of a study on the long-term effects of applying treated domestic wastewater to farmland at Roswell, New Mexico. On the test site, a slow rate irrigation method was used for 33 years. Water, soil, and crop samples from this test site were compared...

  2. Decadal and long-term boreal soil carbon and nitrogen sequestration rates across a variety of ecosystems

    USGS Publications Warehouse

    Manies, Kristen L.; Harden, Jennifer W.; Fuller, Christopher C.; Turetsky, Merritt

    2016-01-01

    Boreal soils play a critical role in the global carbon (C) cycle; therefore, it is important to understand the mechanisms that control soil C accumulation and loss for this region. Examining C & nitrogen (N) accumulation rates over decades to centuries may provide additional understanding of the dominant mechanisms for their storage, which can be masked by seasonal and interannual variability when investigated over the short term. We examined longer-term accumulation rates, using 210Pb and 14C to date soil layers, for a wide variety of boreal ecosystems: a black spruce forest, a shrub ecosystem, a tussock grass ecosystem, a sedge-dominated ecosystem, and a rich fen. All ecosystems had similar decadal C accumulation rates, averaging 84 ± 42 gC m−2 yr−1. Long-term (century) C accumulation rates were slower than decadal rates, averaging 14 ± 5 gC m−2 yr−1 for all ecosystems except the rich fen, for which the long-term C accumulation rates was more similar to decadal rates (44 ± 5 and 76 ± 9 gC m−2 yr−1, respectively). The rich fen also had the highest long-term N accumulation rates (2.7 gN m−2 yr−1). The lowest N accumulation rate, on both a decadal and long-term basis, was found in the black spruce forest (0.2 and 1.4 gN m−2 yr−1, respectively). Our results suggest that the controls on long-term C and N cycling at the rich fen is fundamentally different from the other ecosystems, likely due to differences in the predominant drivers of nutrient cycling (oxygen availability, for C) and reduced amounts of disturbance by fire (for C and N). This result implies that most shifts in ecosystem vegetation across the boreal region, driven by either climate or succession, will not significantly impact regional C or N dynamics over years to decades. However, ecosystem transitions to or from a rich fen will promote significant shifts in soil C and N storage.

  3. Decadal and long-term boreal soil carbon and nitrogen sequestration rates across a variety of ecosystems

    NASA Astrophysics Data System (ADS)

    Manies, Kristen L.; Harden, Jennifer W.; Fuller, Christopher C.; Turetsky, Merritt R.

    2016-08-01

    Boreal soils play a critical role in the global carbon (C) cycle; therefore, it is important to understand the mechanisms that control soil C accumulation and loss for this region. Examining C & nitrogen (N) accumulation rates over decades to centuries may provide additional understanding of the dominant mechanisms for their storage, which can be masked by seasonal and interannual variability when investigated over the short term. We examined longer-term accumulation rates, using 210Pb and 14C to date soil layers, for a wide variety of boreal ecosystems: a black spruce forest, a shrub ecosystem, a tussock grass ecosystem, a sedge-dominated ecosystem, and a rich fen. All ecosystems had similar decadal C accumulation rates, averaging 84 ± 42 gC m-2 yr-1. Long-term (century) C accumulation rates were slower than decadal rates, averaging 14 ± 5 gC m-2 yr-1 for all ecosystems except the rich fen, for which the long-term C accumulation rates was more similar to decadal rates (44 ± 5 and 76 ± 9 gC m-2 yr-1, respectively). The rich fen also had the highest long-term N accumulation rates (2.7 gN m-2 yr-1). The lowest N accumulation rate, on both a decadal and long-term basis, was found in the black spruce forest (0.2 and 1.4 gN m-2 yr-1, respectively). Our results suggest that the controls on long-term C and N cycling at the rich fen is fundamentally different from the other ecosystems, likely due to differences in the predominant drivers of nutrient cycling (oxygen availability, for C) and reduced amounts of disturbance by fire (for C and N). This result implies that most shifts in ecosystem vegetation across the boreal region, driven by either climate or succession, will not significantly impact regional C or N dynamics over years to decades. However, ecosystem transitions to or from a rich fen will promote significant shifts in soil C and N storage.

  4. 78 FR 18664 - Interest Rates

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-27

    ... ADMINISTRATION Interest Rates The Small Business Administration publishes an interest rate called the optional ``peg'' rate (13 CFR 120.214) on a quarterly basis. This rate is a weighted average cost of money to the government for maturities similar to the average SBA direct loan. This rate may be used as a base rate...

  5. Working together in placing the long term interests of the child at the heart of the DSD evaluation.

    PubMed

    Magritte, Ellie

    2012-12-01

    This paper articulates a number of important but often ignored questions that families have during and following the diagnosis of a child with a DSD. Recounting a personal birth experience, it illustrates the urgent need for more psychological and educational support during and following diagnosis and gender assignment. Finally, the paper describes some practical strategies for raising a child living with genital difference. It urges everyone involved in the care of children with a DSD to support parents in looking beyond initial anxiety and worry and always to place the child's long term wellbeing at the very heart of the clinical decision-making and care. PMID:22981141

  6. Long-term care and hospital utilisation by older people: an analysis of substitution rates.

    PubMed

    Forder, Julien

    2009-11-01

    Older people are intensive users of hospital and long-term care services. This paper explores the extent to which these services are substitutes. A small area analysis was used with both care home and (tariff cost-weighted) hospital utilisation for older people aggregated to electoral wards in England.Health and social-care structural equations were specified using a theoretical model. The estimation accounted for the skewed and censored nature of the data. For health utilisation, both a fixed effects instrumental variables GMM model and a generalised estimating equations (GEE) model were fitted, the later on a log dependent variable with predicted values of social care utilisation used to account for endogeneity (bootstrapping was used to derive standard errors). In addition to a GMM model, the social-care estimation used both two-part and tobit models (also with predicted health utilisation and bootstrapping).The results indicate that for each additional pound1 spent on care homes, hospital expenditure falls by pound0.35. Also, pound1 additional hospital spend corresponds to just over pound0.35 reduction on care home spend. With these cost substitution effects offsetting, a transfer of resources to care homes is efficient if the resultant outcome gain is greater than the outcome loss from reduced hospital use. PMID:19206085

  7. Incorporating elastic and plastic work rates into energy balance for long-term tectonic modeling

    NASA Astrophysics Data System (ADS)

    Ahamed, M. S.; Choi, E.

    2014-12-01

    Deformation-related energy budget is usually considered in the simplest form or even completely omitted from the energy balance equation. We derive an energy balance equation that accounts not only for heat energy but also for elastic and plastic work. Such a general description of the energy balance principle will be useful for modeling complicated interactions between geodynamic processes such as thermoelastisity, thermoplasticity and mechanical consequences of metamorphism. Following the theory of large deformation plasticity, we start from the assumption that Gibbs free energy (g) is a function of temperature (T), the second Piola-Kirchhoff stress (S), density (ρ) and internal variables (qj, j=1…n). In this formulation, new terms are derived, which are related to the energy dissipated through plastic work and the elastically stored energy that are not seen in the usual form of the energy balance equation used in geodynamics. We then simplify the generic equation to one involving more familiar quantities such as Cauchy stress and material density assuming that the small deformation formulation holds for our applications. The simplified evolution equation for temperature is implemented in DyanEarthSol3D, an unstructured finite element solver for long-term tectonic deformation. We calculate each of the newly derived terms separately in simple settings and compare the numerical results with a corresponding analytic solution. We also present the effects of the new energy balance on the evolution of a large offset normal fault.

  8. Accelerated forgetting? An evaluation on the use of long-term forgetting rates in patients with memory problems

    PubMed Central

    Geurts, Sofie; van der Werf, Sieberen P.; Kessels, Roy P. C.

    2015-01-01

    The main focus of this review was to evaluate whether long-term forgetting rates (delayed tests, days, to weeks, after initial learning) are more sensitive measures than standard delayed recall measures to detect memory problems in various patient groups. It has been suggested that accelerated forgetting might be characteristic for epilepsy patients, but little research has been performed in other populations. Here, we identified eleven studies in a wide range of brain injured patient groups, whose long-term forgetting patterns were compared to those of healthy controls. Signs of accelerated forgetting were found in three studies. The results of eight studies showed normal forgetting over time for the patient groups. However, most of the studies used only a recognition procedure, after optimizing initial learning. Based on these results, we recommend the use of a combined recall and recognition procedure to examine accelerated forgetting and we discuss the relevance of standard and optimized learning procedures in clinical practice. PMID:26106343

  9. Accelerated forgetting? An evaluation on the use of long-term forgetting rates in patients with memory problems.

    PubMed

    Geurts, Sofie; van der Werf, Sieberen P; Kessels, Roy P C

    2015-01-01

    The main focus of this review was to evaluate whether long-term forgetting rates (delayed tests, days, to weeks, after initial learning) are more sensitive measures than standard delayed recall measures to detect memory problems in various patient groups. It has been suggested that accelerated forgetting might be characteristic for epilepsy patients, but little research has been performed in other populations. Here, we identified eleven studies in a wide range of brain injured patient groups, whose long-term forgetting patterns were compared to those of healthy controls. Signs of accelerated forgetting were found in three studies. The results of eight studies showed normal forgetting over time for the patient groups. However, most of the studies used only a recognition procedure, after optimizing initial learning. Based on these results, we recommend the use of a combined recall and recognition procedure to examine accelerated forgetting and we discuss the relevance of standard and optimized learning procedures in clinical practice. PMID:26106343

  10. Relative Contributions of Geothermal Pumping and Long-Term Earthquake Rate to Seismicity at California Geothermal Fields

    NASA Astrophysics Data System (ADS)

    Weiser, D. A.; Jackson, D. D.

    2015-12-01

    In a tectonically active area, a definitive discrimination between geothermally-induced and tectonic earthquakes is difficult to achieve. We focus our study on California's 11 major geothermal fields: Amedee, Brawley, Casa Diablo, Coso, East Mesa, The Geysers, Heber, Litchfield, Salton Sea, Susanville, and Wendel. The Geysers geothermal field is the world's largest geothermal energy producer. California's Department of Oil Gas and Geothermal Resources provides field-wide monthly injection and production volumes for each of these sites, which allows us to study the relationship between geothermal pumping activities and seismicity. Since many of the geothermal fields began injecting and producing before nearby seismic stations were installed, we use smoothed seismicity since 1932 from the ANSS catalog as a proxy for tectonic earthquake rate. We examine both geothermal pumping and long-term earthquake rate as factors that may control earthquake rate. Rather than focusing only on the largest earthquake, which is essentially a random occurrence in time, we examine how M≥4 earthquake rate density (probability per unit area, time, and magnitude) varies for each field. We estimate relative contributions to the observed earthquake rate of M≥4 from both a long-term earthquake rate (Kagan and Jackson, 2010) and pumping activity. For each geothermal field, respective earthquake catalogs (NCEDC and SCSN) are complete above at least M3 during the test period (which we tailor to each site). We test the hypothesis that the observed earthquake rate at a geothermal site during the test period is a linear combination of the long-term seismicity and pumping rates. We use a grid search to determine the confidence interval of the weighting parameters.

  11. 77 FR 20476 - Interest Rates

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-04

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Interest Rates The Small Business Administration publishes an interest rate called the optional ``peg'' rate (13 CFR 120.214) on a quarterly basis. This rate is a weighted average cost of money to...

  12. 77 FR 59447 - Interest Rates

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-27

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Interest Rates The Small Business Administration publishes an interest rate called the optional ``peg'' rate (13 CFR 120.214) on a quarterly basis. This rate is a weighted average cost of money to the government for maturities similar to...

  13. 75 FR 60152 - Interest Rates

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-29

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Interest Rates The Small Business Administration publishes an interest rate called the optional ``peg'' rate (13 CFR 120.214) on a quarterly basis. This rate is a weighted average cost of money to the government for maturities similar to...

  14. 78 FR 62932 - Interest Rates

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-22

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Interest Rates The Small Business Administration publishes an interest rate called the optional ``peg'' rate (13 CFR 120.214) on a quarterly basis. This rate is a weighted average cost of money to...

  15. 78 FR 39434 - Interest Rates

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-01

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Interest Rates The Small Business Administration publishes an interest rate called the optional ``peg'' rate (13 CFR 120.214) on a quarterly basis. This rate is a weighted average cost of money to...

  16. 77 FR 39560 - Interest Rates

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-03

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Interest Rates The Small Business Administration publishes an interest rate called the optional ``peg'' rate (13 CFR 120.214) on a quarterly basis. This rate is a weighted average cost of money to...

  17. 77 FR 76586 - Interest Rates

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-28

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Interest Rates The Small Business Administration publishes an interest rate called the optional ``peg'' rate (13 CFR 120.214) on a quarterly basis. This rate is a weighted average cost of money to the government for maturities similar to...

  18. 75 FR 81326 - Interest Rates

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-27

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Interest Rates The Small Business Administration publishes an interest rate called the optional ``peg'' rate (13 CFR 120.214) on a quarterly basis. This rate is a weighted average cost of money to...

  19. 76 FR 38717 - Interest Rates

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-01

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Interest Rates The Small Business Administration publishes an interest rate called the optional ``peg'' rate (13 CFR 120.214) on a quarterly basis. This rate is a weighted average cost of money to the government for maturities similar to...

  20. 76 FR 77581 - Interest Rates

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-13

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Interest Rates The Small Business Administration publishes an interest rate called the optional ``peg'' rate (13 CFR 120.214) on a quarterly basis. This rate is a weighted average cost of money to...

  1. 75 FR 37872 - Interest Rates

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-30

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Interest Rates The Small Business Administration publishes an interest rate called the optional ``peg'' rate (13 CFR 120.214) on a quarterly basis. This rate is a weighted average cost of money to the government for maturities similar to...

  2. 76 FR 18821 - Interest Rates

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-05

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Interest Rates The Small Business Administration publishes an interest rate called the optional ``peg'' rate (13 CFR 120.214) on a quarterly basis. This rate is a weighted average cost of money to the government for maturities similar to...

  3. 75 FR 17453 - Interest Rates

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-06

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Interest Rates The Small Business Administration publishes an interest rate called the optional ``peg'' rate (13 CFR 120.214) on a quarterly basis. This rate is a weighted average cost of money to the government for maturities similar to...

  4. Effects of long-term microgravity exposure in space on circadian rhythms of heart rate variability.

    PubMed

    Yamamoto, Naomune; Otsuka, Kuniaki; Kubo, Yutaka; Hayashi, Mitsutoshi; Mizuno, Koh; Ohshima, Hiroshi; Mukai, Chiaki

    2015-04-01

    We evaluated their circadian rhythms using data from electrocardiographic records and examined the change in circadian period related to normal RR intervals for astronauts who completed a long-term (≥6-month) mission in space. The examinees were seven astronauts, five men and two women, from 2009 to 2010. Their mean ± SD age was 52.0 ± 4.2 years (47-59 yr). Each stayed in space for more than 160 days; their average length of stay was 172.6 ± 14.6 days (163-199 days). We conducted a 24-h Holter electrocardiography before launch (Pre), at one month after launch (DF1), at two months after launch (DF2), at two weeks before return (DF3), and at three months after landing (Post), comparing each index of frequency-domain analysis and 24-h biological rhythms of the NN intervals (normal RR intervals). Results show that the mean period of Normal Sinus (NN) intervals was within 24 ± 4 h at each examination. Inter-individual variability differed among the stages, being significantly smaller at DF3 (Pre versus DF1 versus DF3 versus Post = 22.36 ± 2.50 versus 25.46 ± 4.37 versus 22.46 ± 1.75 versus 26.16 ± 7.18 h, p < 0.0001). The HF component increased in 2 of 7 astronauts, whereas it decreased in 3 of 7 astronauts and 1 was remained almost unchanged at DF1. During DF3, about 6 months after their stay in space, the HF component of 5 of 7 astronauts recovered from the decrease after launch, with prominent improvement to over 20% in 3 astronauts. Although autonomic nervous functions and circadian rhythms were disturbed until one month had passed in space, well-scheduled sleep and wake rhythms and meal times served as synchronizers. PMID:25392280

  5. Factors Differentiating Hospital Transfers from Long-term Care Facilities with High and Low Transfer Rates.

    ERIC Educational Resources Information Center

    Teresi, Jeanne A.; And Others

    1991-01-01

    Examined differences among nursing homes in rates at which they transfer patients to hospitals. Data from nursing staff and charts on 286 most recent transfers from 10 nursing homes revealed that, from relatively equivalent patient populations, high-rate facilities transferred more chronically ill, physically frail patients and patients with…

  6. Long-Term Stability of Teacher Certification Test Objective Job Analysis Ratings.

    ERIC Educational Resources Information Center

    Silvestro, John R.; And Others

    Public school ratings of the importance of subject-matter test objectives associated with teacher certification tests were examined by means of a job-analysis survey conducted in 1986 and a similar survey conducted in 1993. It was predicted that there would be a high degree of change in the importance ratings assigned to these test objectives…

  7. Long-term stability of global erosion rates and weathering during late-Cenozoic cooling.

    PubMed

    Willenbring, Jane K; von Blanckenburg, Friedhelm

    2010-05-13

    Over geologic timescales, CO(2) is emitted from the Earth's interior and is removed from the atmosphere by silicate rock weathering and organic carbon burial. This balance is thought to have stabilized greenhouse conditions within a range that ensured habitable conditions. Changes in this balance have been attributed to changes in topographic relief, where varying rates of continental rock weathering and erosion are superimposed on fluctuations in organic carbon burial. Geological strata provide an indirect yet imperfectly preserved record of this change through changing rates of sedimentation. Widespread observations of a recent (0-5-Myr) fourfold increase in global sedimentation rates require a global mechanism to explain them. Accelerated uplift and global cooling have been given as possible causes, but because of the links between rates of erosion and the correlated rate of weathering, an increase in the drawdown of CO(2) that is predicted to follow may be the cause of global climate change instead. However, globally, rates of uplift cannot increase everywhere in the way that apparent sedimentation rates do. Moreover, proxy records of past atmospheric CO(2) provide no evidence for this large reduction in recent CO(2) concentrations. Here we question whether this increase in global weathering and erosion actually occurred and whether the apparent increase in the sedimentation rate is due to observational biases in the sedimentary record. As evidence, we recast the ocean dissolved (10)Be/(9)Be isotope system as a weathering proxy spanning the past approximately 12 Myr (ref. 14). This proxy indicates stable weathering fluxes during the late-Cenozoic era. The sum of these observations shows neither clear evidence for increased erosion nor clear evidence for a pulse in weathered material to the ocean. We conclude that processes different from an increase in denudation caused Cenozoic global cooling, and that global cooling had no profound effect on spatially and

  8. The Effect of Dose Rate on Composite Durability When Exposed to a Simulated Long-Term Lunar Radiation Environment

    NASA Technical Reports Server (NTRS)

    Rojdev, Kristina; O'Rourke, Mary Jane; Hill, Charles; Nutt, Steven; Atwell, William

    2011-01-01

    Human exploration of space beyond low Earth orbit (LEO) requires a safe living and working environment for crew. Composite materials are one type of material being investigated by NASA as a multi-functional structural approach to habitats for long-term use in space or on planetary surfaces with limited magnetic fields and atmosphere. These materials provide high strength with the potential for decreased weight and increased radiation protection of crew and electronics when compared with conventional aluminum structures. However, these materials have not been evaluated in a harsh radiation environment, as would be experienced outside of LEO or on a planetary surface. Thus, NASA has been investigating the durability of select composite materials in a long-term radiation environment. Previously, NASA exposed composite samples to a simulated, accelerated 30-year radiation treatment and tensile stresses similar to those of a habitat pressure vessel. The results showed evidence of potential surface oxidation and enhanced cross-linking of the matrix. As a follow-on study, we performed the same accelerated exposure alongside an exposure with a decreased dose rate. The slower dose ]rate is comparable to a realistic scenario, although still accelerated. Strain measurements were collected during exposure and showed that with a fastdose rate, the strain decreased with time, but with a slow ]dose rate, the strain increased with time. After the radiation exposures, samples were characterized via tensile tests, flexure tests, Fourier Transform Infrared Spectroscopy (FTIR), and Differential Scanning Calorimetry (DSC). The results of these tests will be discussed.

  9. Long-Term Data Reveal Rate and Risk Factors for Subsequent Surgeries Following Initial ACL Reconstruction

    MedlinePlus

    ... we have not known the rate and risk factors for subsequent knee surgery until now,” said senior author Kurt Spindler, M.D., of Vanderbilt University. In the Multicenter Orthopaedic Outcomes Network (MOON) study, ...

  10. Long-term temporal tracking of speech rate affects spoken-word recognition.

    PubMed

    Baese-Berk, Melissa M; Heffner, Christopher C; Dilley, Laura C; Pitt, Mark A; Morrill, Tuuli H; McAuley, J Devin

    2014-08-01

    Humans unconsciously track a wide array of distributional characteristics in their sensory environment. Recent research in spoken-language processing has demonstrated that the speech rate surrounding a target region within an utterance influences which words, and how many words, listeners hear later in that utterance. On the basis of hypotheses that listeners track timing information in speech over long timescales, we investigated the possibility that the perception of words is sensitive to speech rate over such a timescale (e.g., an extended conversation). Results demonstrated that listeners tracked variation in the overall pace of speech over an extended duration (analogous to that of a conversation that listeners might have outside the lab) and that this global speech rate influenced which words listeners reported hearing. The effects of speech rate became stronger over time. Our findings are consistent with the hypothesis that neural entrainment by speech occurs on multiple timescales, some lasting more than an hour. PMID:24907119

  11. Estimating Reservoir Sedimentation Rates: Long-Term Implications for California's Reservoirs

    NASA Astrophysics Data System (ADS)

    Minear, J. T.; Kondolf, G. M.

    2004-12-01

    This paper presents a compilation and analysis of reservoir sedimentation rates applied to unsurveyed reservoirs in California. A number of reservoirs, primarily in the Coast Ranges, have already filled or are nearly filled with sediment and are being considered for removal, including the Matilija, San Clemente, Rindge and Searsville Dams. Of the over 1,400 dams in California listed in the National Inventory of Dams (NID), only 213 (15%) have been surveyed for reservoir sedimentation, presenting a significant gap in current knowledge. Using previously published reports on reservoir sedimentation rates (excluding flood control and debris flow basins), we determined the median reservoir sedimentation rates for the nine different geomorphic regions in California. For the geomorphic regions with sedimentation data, the median sedimentation rate +/- standard error in m3 km-2 yr-1, and (number of measured reservoirs) are: Siskiyou: 340 +/- 170 (3), Coast Range: 220 +/- 50 (49), Central Valley: 145 +/- 90 (5), Sierra Nevada: 95 +/- 25 (23), Transverse Range: 500 +/- 200 (18), and Peninsular Range: 260 +/- 185 (4). These reservoir sedimentation rates were then applied to the unsurveyed reservoirs. Of the approximately 42 million acre-feet of water storage in the state, approximately 5.14 million acre-feet may be currently occupied by sediment, representing a significant decrease of 12% of the state's water supply. Using the same rates to forecast the effects after 50-years, we found that the reservoirs with most risk of sedimentation are primarily small reservoirs (<2,500 acre-feet), such as municipal water-supply reservoirs, especially those operated by coastal towns and cities. Reservoirs in the Coast and Transverse Ranges are the most at risk, with high sedimentation rates, small reservoirs on large watersheds, and older reservoirs. There are over twenty reservoirs that will likely be full or nearly full in 50-years, including Tinemaha, Pleasant Valley, Lee Lake

  12. Analysis of long term heart rate variability: methods, 1/f scaling and implications

    NASA Technical Reports Server (NTRS)

    Saul, J. P.; Albrecht, P.; Berger, R. D.; Cohen, R. J.

    1988-01-01

    The use of spectral techniques to quantify short term heart rate fluctuations on the order of seconds to minutes has helped define the autonomic contributions to beat-to-beat control of heart rate. We used similar techniques to quantify the entire spectrum (0.00003-1.0 Hz) of heart rate variability during 24 hour ambulatory ECG monitoring. The ECG from standard Holter monitor recordings from normal subjects was sampled with the use of a phase locked loop, and a heart rate time series was constructed at 3 Hz. Frequency analysis of the heart rate signal was performed after a nonlinear filtering algorithm was used to eliminate artifacts. A power spectrum of the entire 24 hour record revealed power that was inversely proportional to frequency, 1/f, over 4 decades from 0.00003 to 0.1 Hz (period approximately 10 hours to 10 seconds). Displaying consecutive spectra calculated at 5 minute intervals revealed marked variability in the peaks at all frequencies throughout the 24 hours, probably accounting for the lack of distinct peaks in the spectra of the entire records.

  13. Instrument for precision long-term β-decay rate measurements.

    PubMed

    Ware, M J; Bergeson, S D; Ellsworth, J E; Groesbeck, M; Hansen, J E; Pace, D; Peatross, J

    2015-07-01

    We describe an experimental setup for making precision measurements of relative β-decay rates of (22)Na, (36)Cl, (54)Mn, (60)Co, (90)Sr, (133)Ba, (137)Cs, (152)Eu, and (154)Eu. The radioactive samples are mounted in two automated sample changers that sequentially position the samples with high spatial precision in front of sets of detectors. The set of detectors for one sample changer consists of four Geiger-Müller (GM) tubes and the other set of detectors consists of two NaI scintillators. The statistical uncertainty in the count rate is few times 0.01% per day for the GM detectors and about 0.01% per hour on the NaI detectors. The sample changers, detectors, and associated electronics are housed in a sealed chamber held at constant absolute pressure, humidity, and temperature to isolate the experiment from environmental variations. The apparatus is designed to accumulate statistics over many years in a regulated environment to test recent claims of small annual variations in the decay rates. We demonstrate that absent this environmental regulation, uncontrolled natural atmospheric pressure variations at our location would imprint an annual signal of 0.1% on the Geiger-Müller count rate. However, neither natural pressure variations nor plausible indoor room temperature variations cause a discernible influence on our NaI scintillator detector count rate. PMID:26233381

  14. Instrument for precision long-term β-decay rate measurements

    SciTech Connect

    Ware, M. J. Bergeson, S. D.; Ellsworth, J. E.; Groesbeck, M.; Hansen, J. E.; Pace, D.; Peatross, J.

    2015-07-15

    We describe an experimental setup for making precision measurements of relative β-decay rates of {sup 22}Na, {sup 36}Cl, {sup 54}Mn, {sup 60}Co, {sup 90}Sr, {sup 133}Ba, {sup 137}Cs, {sup 152}Eu, and {sup 154}Eu. The radioactive samples are mounted in two automated sample changers that sequentially position the samples with high spatial precision in front of sets of detectors. The set of detectors for one sample changer consists of four Geiger-Müller (GM) tubes and the other set of detectors consists of two NaI scintillators. The statistical uncertainty in the count rate is few times 0.01% per day for the GM detectors and about 0.01% per hour on the NaI detectors. The sample changers, detectors, and associated electronics are housed in a sealed chamber held at constant absolute pressure, humidity, and temperature to isolate the experiment from environmental variations. The apparatus is designed to accumulate statistics over many years in a regulated environment to test recent claims of small annual variations in the decay rates. We demonstrate that absent this environmental regulation, uncontrolled natural atmospheric pressure variations at our location would imprint an annual signal of 0.1% on the Geiger-Müller count rate. However, neither natural pressure variations nor plausible indoor room temperature variations cause a discernible influence on our NaI scintillator detector count rate.

  15. Instrument for precision long-term β-decay rate measurements

    NASA Astrophysics Data System (ADS)

    Ware, M. J.; Bergeson, S. D.; Ellsworth, J. E.; Groesbeck, M.; Hansen, J. E.; Pace, D.; Peatross, J.

    2015-07-01

    We describe an experimental setup for making precision measurements of relative β-decay rates of 22Na, 36Cl, 54Mn, 60Co, 90Sr, 133Ba, 137Cs, 152Eu, and 154Eu. The radioactive samples are mounted in two automated sample changers that sequentially position the samples with high spatial precision in front of sets of detectors. The set of detectors for one sample changer consists of four Geiger-Müller (GM) tubes and the other set of detectors consists of two NaI scintillators. The statistical uncertainty in the count rate is few times 0.01% per day for the GM detectors and about 0.01% per hour on the NaI detectors. The sample changers, detectors, and associated electronics are housed in a sealed chamber held at constant absolute pressure, humidity, and temperature to isolate the experiment from environmental variations. The apparatus is designed to accumulate statistics over many years in a regulated environment to test recent claims of small annual variations in the decay rates. We demonstrate that absent this environmental regulation, uncontrolled natural atmospheric pressure variations at our location would imprint an annual signal of 0.1% on the Geiger-Müller count rate. However, neither natural pressure variations nor plausible indoor room temperature variations cause a discernible influence on our NaI scintillator detector count rate.

  16. Bluff formation and long-term recession rates, southwestern Lake Michigan

    SciTech Connect

    Rovey, C.W. II )

    1992-01-01

    Where eroding cohesive sediments are present, Lake Michigan bluffs range up to 140 ft. in height and expose multiple stratigraphic units. According to the model presented here, bluffs form as a wave cut terrace erodes inland from a point near the original shoreline. The erosion plane is nearly horizontal, in contrast with the eastward dip of the glacial units inherited from underlying bedrock. Therefore, terraces eroding inland (west) produce progressively higher bluffs and expose successively older units at the toe and beneath the lake. This process repeated several times as lake levels sequentially dropped to their modern stage. The initial modern shoreline, and hence the width of the wave cut terrace, was determined from 4 offshore seismic profiles. It is picked as an inflection point in the slope of the lake bed, occurring offshore of dipping reflectors intersecting the lake bottom. The calculated average recession rate over the 2,500 year duration of the modern stage is 5 ft/yr in contrast to average rates of 2 ft/yr measured over the last century. Thus rates decrease through time as the terrace widens and wave energy is damped. By correlating bluff height to amount of recession of modern bluffs, a third rate of 12 ft/yr of the first 800 years of a recession is calculated for relict bluffs formed at the Nipissing II level. The 3 rates define a steeply decaying exponential curve in early stages of bluff retreat, flattening into a nearly linear function after 1,000 years.

  17. Complementary system for long term measurements of radon exhalation rate from soil

    SciTech Connect

    Mazur, J.; Kozak, K.

    2014-02-15

    A special set-up for continuous measurements of radon exhalation rate from soil is presented. It was constructed at Laboratory of Radiometric Expertise, Institute of Nuclear Physics Polish Academy of Sciences (IFJ PAN), Krakow, Poland. Radon exhalation rate was determined using the AlphaGUARD PQ2000 PRO (Genitron) radon monitor together with a special accumulation container which was put on the soil surface during the measurement. A special automatic device was built and used to raise and lower back onto the ground the accumulation container. The time of raising and putting down the container was controlled by an electronic timer. This set-up made it possible to perform 4–6 automatic measurements a day. Besides, some additional soil and meteorological parameters were continuously monitored. In this way, the diurnal and seasonal variability of radon exhalation rate from soil can be studied as well as its dependence on soil properties and meteorological conditions.

  18. Long-term evolution of biodegradation and volatilization rates in a crude oil-contaminated aquifer

    USGS Publications Warehouse

    Chaplin, B.P.; Delin, G.N.; Baker, R.J.; Lahvis, M.A.

    2002-01-01

    Volatilization and subsequent biodegradation near the water Table make up a coupled natural attenuation pathway that results in significant mass loss of hydrocarbons. Rates of biodegradation and volatilization were documented twice 12 years apart at a crude-oil spill site near Bemidji, Minnesota. Biodegradation rates were determined by calibrating a gas transport model to O2, CO2, and CH4 gas-concentration data in the unsaturated zone. Reaction stoichiometry was assumed in converting O2 and CO2 gas-flux estimates to rates of aerobic biodegradation and CH4 gas-flux estimates to rates of methanogenesis. Model results indicate that the coupled pathway has resulted in significant hydrocarbon mass loss at the site, and it was estimated that approximately 10.52 kg/day were lost in 1985 and 1.99 kg/day in 1997. In 1985 3% of total volatile hydrocarbons diffusing from the floating oil were biodegraded in the lower 1 m of the unsaturated zone and increased to 52% by 1997. Rates of hydrocarbon biodegradation above the center of the floating oil were relatively stable from 1985 to 1997, as the primary metabolic pathway shifted from aerobic to methanogenic biodegradation. Model results indicate that in 1997 biodegradation under methanogenenic conditions represented approximately one-half of total hydrocarbon biodegradation in the lower 1 m of the unsaturated zone. Further downgradient, where substrate concentrations have greatly increased, total biodegradation rates increased by greater than an order of magnitude from 0.04 to 0.43 g/m2-day. It appears that volatilization is the primary mechanism for attenuation in early stages of plume evolution, while biodegradation dominates in later stages.

  19. Long-Term evolution of the erosion rates during Early Mars

    NASA Astrophysics Data System (ADS)

    Quantin-Nataf, C.; Craddock, R. A.; Dubuffet, F.; Lozac'h, L.; Martinot, M.

    2015-10-01

    Many Geologic features attest to the fact that liquid water was once stable on the Martian surface. The erosional processes necessary to create these features must have been supported by a climate that is much different than today. However, the evolution of these primitives conditions toward the current dry and cold Martian climate where the erosion processes are 2-3 orders in magnitude lower represents a major gap in our understanding of the evolution of Mars history. Here we document the time-dependence of the erosion rates on Mars during early Mars, period during which the erosion rates have decreased of at least one order in magnitude.

  20. The Greenville Fault: preliminary estimates of its long-term creep rate and seismic potential

    USGS Publications Warehouse

    Lienkaemper, James J.; Barry, Robert G.; Smith, Forrest E.; Mello, Joseph D.; McFarland, Forrest S.

    2013-01-01

    Once assumed locked, we show that the northern third of the Greenville fault (GF) creeps at 2 mm/yr, based on 47 yr of trilateration net data. This northern GF creep rate equals its 11-ka slip rate, suggesting a low strain accumulation rate. In 1980, the GF, easternmost strand of the San Andreas fault system east of San Francisco Bay, produced a Mw5.8 earthquake with a 6-km surface rupture and dextral slip growing to ≥2 cm on cracks over a few weeks. Trilateration shows a 10-cm post-1980 transient slip ending in 1984. Analysis of 2000-2012 crustal velocities on continuous global positioning system stations, allows creep rates of ~2 mm/yr on the northern GF, 0-1 mm/yr on the central GF, and ~0 mm/yr on its southern third. Modeled depth ranges of creep along the GF allow 5-25% aseismic release. Greater locking in the southern two thirds of the GF is consistent with paleoseismic evidence there for large late Holocene ruptures. Because the GF lacks large (>1 km) discontinuities likely to arrest higher (~1 m) slip ruptures, we expect full-length (54-km) ruptures to occur that include the northern creeping zone. We estimate sufficient strain accumulation on the entire GF to produce Mw6.9 earthquakes with a mean recurrence of ~575 yr. While the creeping 16-km northern part has the potential to produce a Mw6.2 event in 240 yr, it may rupture in both moderate (1980) and large events. These two-dimensional-model estimates of creep rate along the southern GF need verification with small aperture surveys.

  1. A long-term perspective on deforestation rates in the Brazilian Amazon

    NASA Astrophysics Data System (ADS)

    Velasco Gomez, M. D.; Beuchle, R.; Shimabukuro, Y.; Grecchi, R.; Simonetti, D.; Eva, H. D.; Achard, F.

    2015-04-01

    Monitoring tropical forest cover is central to biodiversity preservation, terrestrial carbon stocks, essential ecosystem and climate functions, and ultimately, sustainable economic development. The Amazon forest is the Earth's largest rainforest, and despite intensive studies on current deforestation rates, relatively little is known as to how these compare to historic (pre 1985) deforestation rates. We quantified land cover change between 1975 and 2014 in the so-called Arc of Deforestation of the Brazilian Amazon, covering the southern stretch of the Amazon forest and part of the Cerrado biome. We applied a consistent method that made use of data from Landsat sensors: Multispectral Scanner (MSS), Thematic Mapper (TM), Enhanced Thematic Mapper Plus (ETM+) and Operational Land Imager (OLI). We acquired suitable images from the US Geological Survey (USGS) for five epochs: 1975, 1990, 2000, 2010, and 2014. We then performed land cover analysis for each epoch using a systematic sample of 156 sites, each one covering 10 km x 10 km, located at the confluence point of integer degree latitudes and longitudes. An object-based classification of the images was performed with five land cover classes: tree cover, tree cover mosaic, other wooded land, other land cover, and water. The automatic classification results were corrected by visual interpretation, and, when available, by comparison with higher resolution imagery. Our results show a decrease of forest cover of 24.2% in the last 40 years in the Brazilian Arc of Deforestation, with an average yearly net forest cover change rate of -0.71% for the 39 years considered.

  2. Long-term results of breast cancer irradiation treatment with low-dose-rate external irradiation

    SciTech Connect

    Pierquin, Bernard; Tubiana, Maurice . E-mail: maurice.tubiana@biomedicale.univ-paris5.fr; Pan, Camille; Lagrange, Jean-Leon; Calitchi, Elie; Otmezguine, Yves

    2007-01-01

    Purpose: The aim of this study was to assess beam therapy with low-dose-rate (LDR) external irradiation in a group of patients with breast cancer. Methods and Materials: This trial compared, from 1986 to 1989, patients with advanced breast cancer treated either by conventional fractionation or low-dose-rate (LDR) external radiotherapy (dose-rate 15 mGy/min, 5 sessions of 9 Gy delivered on 5 consecutive days). Results: A total of 21 patients were included in the fractionated therapy arm. At follow-up 15 years after treatment, 7 local recurrences had occurred, 3 patients had died of cancer, 18 patients were alive, 10 were without evidence of disease, and 6 had evidence of disease. A total of 22 patients had been included in the LDR arm of the study. Of these, 11 had received a dose of 45 Gy; thereafter, in view of severe local reactions, the dose was reduced to 35 Gy. There was no local recurrence in patients who had received 45 Gy, although there were 2 local recurrences among the 11 patients after 35 Gy. The sequelae were severe in patients who received 45 Gy but were comparable to those observed in patients treated by fractionated radiotherapy who received 35 Gy. The higher efficacy of tumor control in patients treated by LDR irradiation as well as the lower tolerance of normal tissue are probably related to the lack of repopulation. Conclusion: Although the patient numbers in this study are limited, based on our study results we conclude that the data for LDR irradiation are encouraging and that further investigation is warranted.

  3. Interest rate swaps under CIR

    NASA Astrophysics Data System (ADS)

    Mallier, R.; Alobaidi, G.

    2004-03-01

    We consider fixed-for-floating interest rate swaps under the assumption that interest rates are given by the mean-reverting Cox-Ingersoll-Ross model. By using a Green's function approach, we derive analytical expressions for the values of both a vanilla swap and an in-arrears swap.

  4. High failure rate in spinal ependymomas with long-term follow-up1

    PubMed Central

    Gomez, Daniel R.; Missett, Brian T.; Wara, William M.; Lamborn, Kathleen R.; Prados, Michael D.; Chang, Susan; Berger, Mitchel S.; Haas-Kogan, Daphne A.

    2005-01-01

    Data on spinal ependymomas are sparse, and prognostic factors remain controversial. The primary aim of this study is to review a historical cohort, with large patient numbers and long follow-up, and provide estimates of time to progression (TTP) and survival after progression. As a secondary aim, we assess the effects of potential prognostic variables. Thirty-seven patients with spinal cord ependymomas received postoperative radiation therapy from 1955 to 2001. The influences of radiation dose, extent of resection, Karnofsky performance score, tumor location, and multifocality were assessed in univariate analyses by using the Cox proportional hazards model. The median follow-up for patients who did not fail was 121 months (range, 8–312 months). Kaplan-Meier estimates of 5-, 10-, and 15-year percentage progression free are 75% ± 7.4%, 50% ± 9.1%, and 46% ± 9.3%, respectively. Median TTP, for those who recurred, is 68 months (range, 2–324 months), with 12 of 21 failures occurring after five years. Of the prognostic factors examined, only greater extent of resection significantly correlated with longer TTP (P = 0.02). Local relapse rates for spinal ependymomas are higher than previously cited, with a large proportion of failures occurring more than five years after diagnosis. Extensive surgical resection correlates with longer time to recurrence, and we thus recommend maximal excision while avoiding surgical morbidity. The overall high rate of recurrence leads us to recommend radiation to doses of 45 to 54 Gy for all patients who do not have gross total resections, and long, close follow-up. PMID:16053700

  5. Impact of basal heart rate on long-term prognosis of heart transplant patients.

    PubMed

    Melero-Ferrer, Josep L; Sánchez-Lázaro, Ignacio J; Almenar-Bonet, Luis; Martínez-Dolz, Luis; Buendía-Fuentes, Francisco; Portolés-Sanz, Manuel; Rivera-Otero, Miguel; Salvador-Sanz, Antonio

    2013-05-01

    Previous studies in patients with heart failure have shown that an elevated basal heart rate (HR) is associated with a poor outcome. Our aim with this study was to investigate if this relationship is also present in heart transplantation (HTx) recipients. From 2003 until 2010, 256 HTx performed in our center were recruited. Patients who required pacemaker, heart-lung transplants, pediatrics, retransplants, and those patients with a survival of less than 1 year were excluded. The final number included in the analysis was 191. Using the HR obtained by EKG during elective admission at 1 year post-HTx and the survival rate, an ROC-curve was performed. The best point under the curve was achieved with 101 beats per minute (bpm), so patients were divided in two groups according to their HR. A comparison between survival curves of both groups was performed (Kaplan-Meier). Subsequently, a multivariate analysis considering HR and other variables with influence on survival according to the literature was carried out. A total of 136 patients were included in the group with HR ≤100 bpm, and 55 in the one with HR >100 bpm. There were no basal differences in both groups except for primary graft failure, which was more frequent in the >100 bpm group (30.9 vs. 17%, P = 0.033). Patients with ≤100 bpm had a better long prognosis (P < 0.001). The multivariate analysis proved that high HR was an independent predictor of mortality. Our study shows that HR should be considered as a prognosis factor in HTx patients. PMID:23489468

  6. Towards quantifying long-term erosion rates in the Campine Basin, NE Belgium

    NASA Astrophysics Data System (ADS)

    Beerten, Koen; Vanacker, Veerle

    2016-04-01

    The Campine Basin, NE Belgium, is situated between the uplifting Ardennes Massif and rapidly subsiding Roer Valley Graben. It contains a thick series of marine, estuarine and continental Neogene and Quaternary sediments, locally more than 300 m. As a result of relief inversion during the Quaternary, the Campine Plateau is nowadays a distinct morphological feature in this basin. Its surface elevation dips from 100 m in the south to 30 m in the north over a distance of about 60 km, which is the result of differential uplift. The Campine Plateau is covered by Early and Middle Pleistocene erosion-resistant fluvial sediments from the Rhine and Meuse and can thus be regarded as a fluvial terrace. The age of deposition and time of abandonment of the terrace have not yet been resolved by direct numerical dating. In this study, we apply the cosmogenic radionuclide (CRN) profiling technique that, in ideal circumstances, allows one to constrain the exposure age, burial age and amount of post-depositional erosion of the landform. Samples were taken from a 3.5 m deep cross-section in coarse river sands that were deposited by the river Rhine, and now situated at an altitude of about 50 m (a.s.l.). Nine of them were prepared for CRN measurements according to state-of-the-art techniques. The in-situ 10Be concentration of the samples was determined using accelerator mass spectrometry (ETH, Zurich). The in-situ 10Be concentrations are 1.5x10e5 atoms/g for the uppermost sample (at 0.3 m depth) and 0.9x10e5 at/g for the lowermost sample (at 3.1 m depth), yielding an estimated 0.6x10e5 at/g of radionuclide accumulation following sediment deposition. Using forward modelling, we solved for the exposure duration and erosion rate that best fit the measured in-situ 10Be depth profile data, nuclide inheritance and their associated analytical uncertainties. Model optimisation is here based on the sum of chi-squared between the measured and modelled 10Be concentrations. When taking previous

  7. Long-term variation of OH peak emission altitude and volume emission rate over Indian low latitudes

    NASA Astrophysics Data System (ADS)

    Sivakandan, Mani; Thokuluwa, Ramkumar; Kandula, Niranjan; Taori, Alok

    2016-07-01

    Using 13 (April 2002 -December 2014) years of Sounding of the Atmosphere using Broadband Emission Radiometry (SABER/TIMED) 1.6µm OH airglow emission data, we have studied the long-term variation of OH peak emission altitude and volume emission rate (VER) for 0-10 N latitude and 70-90 E longitude grid. We have noted that, during day time the OH peak emission altitude is varying from 80 to 87 km with mean value of 83.5 km and from 82 to 88 km with mean value of 85 km during night time. The signature of semi-annual oscillation (SAO), annual oscillation (AO) and quasi-biennial oscillation (QBO) in the OH peak emission altitude as well as the VER is evident. Our analysis reveals that the SAO and QBO signatures but not the AO signature are very strong in the equatorial region during night time. Apart from the SAO, AO and QBO signatures, the presence of oscillation related to the El Niño oscillation (ENSO) is also noted. After the removal of these oscillations, we find the evidence of the influence of solar activity and a long term trend in the OH emission layer. It is also found good correlation between the mesospheric and stratospheric variations (ECMWF data).

  8. Long-term variation of OH peak emission altitude and volume emission rate over Indian low latitudes

    NASA Astrophysics Data System (ADS)

    Sivakandan, M.; Ramkumar, T. K.; Taori, A.; Rao, Venkateshwara; Niranjan, K.

    2016-02-01

    Using 13 (April 2002-December 2014) years of Sounding of the Atmosphere using Broadband Emission Radiometry (SABER/TIMED) 1.6 μm OH airglow emission data, we have studied the long-term variation of OH peak emission altitude and volume emission rate (VER) for 0-10°N latitude and 70-90°E longitude grid. We have noted that, during day time the OH peak emission altitude is varying from 80 to 87 km with mean value of 83.5 km and from 82 to 88 km with mean value of 85 km during night time. The signature of semi-annual oscillation (SAO), annual oscillation (AO) and quasi-biennial oscillation (QBO) in the OH peak emission altitude as well as the VER is evident. Our analysis reveals that the SAO and QBO signatures but not the AO signature are very strong in the equatorial region during night time. Apart from the SAO, AO and QBO signatures, the presence of oscillation related to the El Niño oscillation (ENSO) is also noted. After the removal of these oscillations, we find the evidence of the influence of solar activity and a long term trend in the OH emission layer. It is also found good correlation between the mesospheric and stratospheric variations (ECMWF data).

  9. Recurrence rates in bipolar disorder: Systematic comparison of long-term prospective, naturalistic studies versus randomized controlled trials.

    PubMed

    Vázquez, Gustavo H; Holtzman, Jessica N; Lolich, María; Ketter, Terence A; Baldessarini, Ross J

    2015-10-01

    Bipolar disorder (BD) is a recurrent, lifelong illness with high risks of disability and excess mortality. Despite many treatment options with demonstrated short-term efficacy, evidence concerning long-term treatment effectiveness in BD remains limited and the relative value of naturalistic studies versus randomized, controlled trials (RCTs) in its assessment, uncertain. Systematic computer-searching yielded 10 naturalistic studies and 15 RCTs suitable for analysis of recurrence rates and their association with treatments and selected clinical factors. In naturalistic studies (3904 BD subjects, 53.3% women, 85.8% BD-I, mean onset age 29.1, followed up to 2.1 years), the pooled recurrence rate was 55.2% (26.3%/year). In RCTs (4828 subjects, 50.9% women, 96.0% BD-I, mean onset age 23.1, followed up to 1.9 years), the pooled recurrence rate was 39.3% (21.9%/year) with mood-stabilizing drug-treatment versus 60.6% (31.3%/year) with placebo; drug-versus-placebo outcomes favored antipsychotics over lithium, and disfavor an approved anticonvulsant. Depressive episode-polarity increased from 27.7% at intake to 52.0% at first-recurrence (p<0.0001). Recurrence rate (%/year) did not differ by study-type, was greater with younger onset and rapid-cycling, and paradoxically declined with longer observation. In short, recurrences of major affective episodes up to two years during putative mood-stabilizing treatment of BD patients in prospective, naturalistic studies and RCTs were substantial and similar (26.3 vs. 21.9%/year). Episode-polarity shifted strongly toward depressive first-recurrences. These findings support the value of naturalistic studies to complement long-term RCTs, and add to indications that control of depression in BD remains particularly unsatisfactory. PMID:26238969

  10. Styles and rates of long-term denudation in carbonate terrains under a Mediterranean to hyper-arid climatic gradient

    NASA Astrophysics Data System (ADS)

    Ryb, U.; Matmon, A.; Erel, Y.; Haviv, I.; Benedetti, L.; Hidy, A. J.

    2014-11-01

    Carbonate minerals, unlike silicates, have the potential to dissolve almost completely and with high efficiency. Thus, in carbonate terrains denudation rate and style (the governing process of denudation, mechanical or chemical) should be more sensitive to climatic forcing. Using 36Cl measurements in 39 carbonate bedrock and sediment samples, we calculate long-term denudation rates across a sharp climatic gradient from Mediterranean to hyper-arid conditions. Our samples were collected along the Arugot watershed, which drains the eastern flank of the Judea Range (central Israel) to the Dead Sea and is characterized by a pronounced rain shadow. Denudation rates of flat-lying bedrock outcrops sampled along interfluves differ by an order of magnitude from ∼20 mm ka-1 in the Mediterranean zone to 1-3 mm ka-1 in the hyper-arid zone. These rates are strongly correlated with precipitation, and thus reflect the importance of carbonate mineral dissolution in the overall denudation process. In contrast, denudation rates of steep bedrock surfaces depend on the hillslope gradient, but only in the hyper-arid climate zone, indicating that mechanical processes dominate the overall hillslope denudation within this zone. The dominance of slope-dependent mechanical erosion in the hyper-arid zone is also reflected by an increase in spatially-average denudation rates from 17-19 mm ka-1 in the Mediterranean-semi-arid zones to 21-25 mm ka-1 in the hyper-arid zone. These higher rates are attributed to clast contribution from steep slopes under arid climate. This suggests an increased importance of mechanical processes to the overall denudation in the hyper-arid zone. We demonstrate that the transition between chemically-dominated denudation to mechanically-dominated denudation occurs between 100 and 200 mm of mean annual precipitation. Long-term denudation rates across the Judea Range indicate that between Mediterranean and hyper-arid climates, chemical weathering rates are limited by

  11. Effect of the Presence of Long Term Correlated Common Source Fluctuations to the Heart Rate Feedback Analysis

    NASA Astrophysics Data System (ADS)

    Nishiyama, S.; Yana, K.; Mizuta, H.; Ono, T.

    2007-07-01

    This paper investigates the effect of the presence of long term correlated common driving forces to the bivariate autoregressive (BAR) analysis for the closed loop characterization of heart rate fluctuations (HRF) and systolic blood pressure change (SBP). It has been shown that the estimation accuracy decreases as common noise power and Hurst parameter value increases. However, the accuracy is acceptable even with relatively high common driving force power at 50% and with high Hurst parameter values at 0.95. The relative mean squared error in the impulse response estimation is shown to be 12% in that ill condition. As an illustrative example of the bivariate fluctuation analysis, the change in impulse responses between HRF and SBP due to the water intake has been examined.

  12. Drivers and annual estimates of marine wildlife entanglement rates: A long-term case study with Australian fur seals.

    PubMed

    McIntosh, Rebecca R; Kirkwood, Roger; Sutherland, Duncan R; Dann, Peter

    2015-12-30

    Methods of calculating wildlife entanglement rates are not standardised between studies and often ignore the influence of observer effort, confounding comparisons. From 1997-2013 we identified 359 entangled Australian fur seals at Seal Rocks, south-eastern Australia. Most entanglement materials originated from commercial fisheries; most frequently entangling pups and juveniles. Using Generalized Additive Mixed Models, which incorporated observer effort and survey frequency, we identified that entanglements were observed more frequently amongst pups from July to October as they approached weaning. Neither the decline in regional fishing intensity nor changing seal population size influenced the incidence of entanglements. Using the models, we estimated that 302 (95% CI=182-510) entangled seals were at Seal Rocks each year, equivalent to 1.0% (CI=0.6-1.7%) of the site population. This study highlights the influence of observer effort and the value of long-term datasets for determining the drivers of marine debris entanglements. PMID:26475026

  13. Effects of vaccination against viral haemorrhagic disease and myxomatosis on long-term mortality rates of European wild rabbits.

    PubMed

    Calvete, C; Estrada, R; Lucientes, J; Osacar, J J; Villafuerte, R

    2004-09-25

    The effects of vaccination against myxomatosis and viral haemorrhagic disease (VHD) on long-term mortality rates in European rabbits (Oryctolagus cuniculus) were studied from 1993 to 1996 by radiotracking a free-living population of wild rabbits. During the three months after immunisation, unvaccinated young rabbits weighing between 180 and 600 g were 13.6 times more likely to die than vaccinated young rabbits. In adult rabbits, vaccination did not significantly decrease mortality, mainly owing to the high proportion of rabbits which had previously been exposed to the antigens of both diseases. Compared with adult rabbits with natural antibodies to VHD, rabbits without these antibodies were 5.2 times more likely to die of VHD during annual outbreaks. PMID:15499810

  14. Long-term influence of tillage and fertilization on net carbon dioxide exchange rate on two soils with different textures.

    PubMed

    Feiziene, Dalia; Feiza, Virginijus; Slepetiene, Alvyra; Liaudanskiene, Inga; Kadziene, Grazina; Deveikyte, Irena; Vaideliene, Asta

    2011-01-01

    The importance of agricultural practices to greenhouse gas mitigation is examined worldwide. However, there is no consensus on soil organic carbon (SOC) content and CO emissions as affected by soil management practices and their relationships with soil texture. No-till (NT) agriculture often results in soil C gain, though, not always. Soil net CO exchange rate (NCER) and environmental factors (SOC, soil temperature [T], and water content [W]), as affected by soil type (loam and sandy loam), tillage (conventional, reduced, and NT), and fertilization, were quantified in long-term field experiments in Lithuania. Soil tillage and fertilization affected total CO flux (heterotrophic and autotrophic) through effect on soil SOC sequestration, water, and temperature regime. After 11 yr of different tillage and fertilization management, SOC content was 23% more in loam than in sandy loam. Long-term NT contributed to 7 to 27% more SOC sequestration on loam and to 29 to 33% more on sandy loam compared with reduced tillage (RT) or conventional tillage (CT). Soil water content in loam was 7% more than in sandy loam. Soil gravimetric water content, averaged across measurement dates and fertilization treatments, was significantly less in NT than CT and RT in both soils. Soil organic carbon content and water storage capacity of the loam and sandy loam soils exerted different influences on NCER. The NCER from the sandy loam soil was 13% greater than that from the loam. In addition, NCER was 4 to 9% less with NT than with CT and RT systems on both loam and sandy loam soils. Application of mineral NPK fertilizers promoted significantly greater NCER from loam but suppressed NCER by 15% from sandy loam. PMID:22031561

  15. Observations of historical sea cliff retreat rates exceed long-term estimates derived from cosmogenic 10Be

    NASA Astrophysics Data System (ADS)

    Hurst, Martin D.; Rood, Dylan H.; Ellis, Michael A.; Anderson, Robert S.

    2015-04-01

    Historical observation of coastal retreat are limited to relatively short timescales (< 150 years), during which time humans may have modified the coastal environment. There is growing concern that rates of coastal change may be accelerated in the face of anticipated stormier climates and rising sea level, yet there is little knowledge of rates of coastal change prior to the relatively brief historical records. In order to make predictions about potential future coastal change it is important to establish baseline conditions averaged over longer time periods. Here we present analysis of sea cliff retreat throughout the Holocene averaged for chalk cliffs in south-east England using cosmogenic isotopes. We determine long-term rates of sea cliff erosion from 10Be measured from in-situ flint samples collected from three transects across coastal platforms in East Sussex. A numerical model of 10Be accumulation on an evolving coastal profile allows estimation of cliff retreat rate during the Holocene. The model accounts for variation in 10Be accumulation with tides and sea-level rise, and takes into account platform downwear and topographic shielding by adjacent cliffs. We find that cliff retreat rates during the Holocene were significantly slower (2-6 cm yr-1) than those derived from recent historical observations (15-25 cm yr-1). Modelled accumulation of 10Be requires retreat rates that increase rapidly in recent times, potentially reflecting human modification of the coastal sediment budget through construction of sea defences, flood defenses and aggregate extraction. Therefore knowledge of past human activity at the coastline may be important in anticipating future rates of coastal retreat.

  16. Classification tree for risk assessment in patients suffering from congestive heart failure via long-term heart rate variability.

    PubMed

    Melillo, Paolo; De Luca, Nicola; Bracale, Marcello; Pecchia, Leandro

    2013-05-01

    This study aims to develop an automatic classifier for risk assessment in patients suffering from congestive heart failure (CHF). The proposed classifier separates lower risk patients from higher risk ones, using standard long-term heart rate variability (HRV) measures. Patients are labeled as lower or higher risk according to the New York Heart Association classification (NYHA). A retrospective analysis on two public Holter databases was performed, analyzing the data of 12 patients suffering from mild CHF (NYHA I and II), labeled as lower risk, and 32 suffering from severe CHF (NYHA III and IV), labeled as higher risk. Only patients with a fraction of total heartbeats intervals (RR) classified as normal-to-normal (NN) intervals (NN/RR) higher than 80% were selected as eligible in order to have a satisfactory signal quality. Classification and regression tree (CART) was employed to develop the classifiers. A total of 30 higher risk and 11 lower risk patients were included in the analysis. The proposed classification trees achieved a sensitivity and a specificity rate of 93.3% and 63.6%, respectively, in identifying higher risk patients. Finally, the rules obtained by CART are comprehensible and consistent with the consensus showed by previous studies that depressed HRV is a useful tool for risk assessment in patients suffering from CHF. PMID:24592473

  17. Determination of longevities, chamber building rates and growth functions for Operculina complanata from long term cultivation experiments

    NASA Astrophysics Data System (ADS)

    Woeger, Julia; Kinoshita, Shunichi; Wolfgang, Eder; Briguglio, Antonino; Hohenegger, Johann

    2016-04-01

    Operculina complanata was collected in 20 and 50 m depth around the Island of Sesoko belonging to Japans southernmost prefecture Okinawa in a series of monthly sampling over a period of 16 months (Apr.2014-July2015). A minimum of 8 specimens (4 among the smallest and 4 among the largest) per sampling were cultured in a long term experiment that was set up to approximate conditions in the field as closely as possible. A set up allowing recognition of individual specimens enabled consistent documentation of chamber formation, which in combination with μ-CT-scanning after the investigation period permitted the assignment of growth steps to specific time periods. These data were used to fit various mathematical models to describe growth (exponential-, logistic-, generalized logistic-, Gompertz-function) and chamber building rate (Michaelis-Menten-, Bertalanffy- function) of Operculina complanata. The mathematically retrieved maximum lifespan and mean chamber building rate found in cultured Operculina complanata were further compared to first results obtained by the simultaneously conducted "natural laboratory approach". Even though these comparisons hint at a somewhat stunted growth and truncated life spans of Operculina complanata in culture, they represent a possibility to assess and improve the quality of further cultivation set ups, opening new prospects to a better understanding of the their theoretical niches.

  18. Effects of long-term dharma-chan meditation on cardiorespiratory synchronization and heart rate variability behavior.

    PubMed

    Chang, Chih-Hao; Lo, Pei-Chen

    2013-04-01

    Remarkable changes in cardiorespiratory interactions are frequently experienced by Chan meditation practitioners following years of practice. This study compares the results of our study on cardiorespiratory interactions for novice (control group) and experienced (experimental group) Chan meditation practitioners. The effectual co-action between the cardiac and respiratory systems was evaluated by the degree of cardiorespiratory phase synchronization (CRPS). In addition, an adaptive-frequency-range (AFR) scheme to reliably quantify heart rate variability (HRV) was developed for assessing the regulation of sympathetic-parasympathetic activity and the efficiency of pulmonary gas exchange. The enhanced HRV method, named HRVAFR, can resolve the issue of overestimating HRV under the condition of slow respiration rates, which is frequently encountered in studies on Chan meditation practitioners. In the comparison of the three data sets collected from the two groups, our findings resulted in innovative hypotheses to interpret the extraordinary process of the rejuvenation of cardiorespiratory functions through long-term Dharma-Chan meditation practice. Particularly, advanced practitioners exhibit a continuously high degree of cardiorespiratory phase synchronization, even during rapid breathing. Based on our post-experimental interview with advanced practitioners, the activation of inner Chakra energy, during the course of Chan-detachment practice, frequently induces perceptible physiological-mental reformation, including an efficient mechanism for regulating cardiorespiratory interactions. PMID:23323597

  19. Effects of Long-Term Dharma-Chan Meditation on Cardiorespiratory Synchronization and Heart Rate Variability Behavior

    PubMed Central

    Chang, Chih-Hao

    2013-01-01

    Abstract Remarkable changes in cardiorespiratory interactions are frequently experienced by Chan meditation practitioners following years of practice. This study compares the results of our study on cardiorespiratory interactions for novice (control group) and experienced (experimental group) Chan meditation practitioners. The effectual co-action between the cardiac and respiratory systems was evaluated by the degree of cardiorespiratory phase synchronization (CRPS). In addition, an adaptive-frequency-range (AFR) scheme to reliably quantify heart rate variability (HRV) was developed for assessing the regulation of sympathetic–parasympathetic activity and the efficiency of pulmonary gas exchange. The enhanced HRV method, named HRVAFR, can resolve the issue of overestimating HRV under the condition of slow respiration rates, which is frequently encountered in studies on Chan meditation practitioners. In the comparison of the three data sets collected from the two groups, our findings resulted in innovative hypotheses to interpret the extraordinary process of the rejuvenation of cardiorespiratory functions through long-term Dharma-Chan meditation practice. Particularly, advanced practitioners exhibit a continuously high degree of cardiorespiratory phase synchronization, even during rapid breathing. Based on our post-experimental interview with advanced practitioners, the activation of inner Chakra energy, during the course of Chan-detachment practice, frequently induces perceptible physiological-mental reformation, including an efficient mechanism for regulating cardiorespiratory interactions. PMID:23323597

  20. Forced migration and mortality in the very long term: did perestroika affect death rates also in Finland?

    PubMed

    Saarela, Jan; Finnäs, Fjalar

    2009-08-01

    In this article, we analyze mortality rates of Finns born in areas that were ceded to the Soviet Union after World War II and from which the entire population was evacuated. These internally displaced persons are observed during the period 1971-2004 and compared with people born in the same region but on the adjacent side of the new border. We find that in the 1970s and 1980s, the forced migrants had mortality rates that were on par with those of people in the comparison group. In the late 1980s, the mortality risk of internally displaced men increased by 20% in relation to the expected time trend. This deviation, which manifests particularly in cardiovascular mortality, coincides with perestroika and the demise of the Soviet Union, which were events that resulted in an intense debate in civil society about restitution of the ceded areas. Because state actors were reluctant to engage, the debate declined after some few years, and after the mid-1990s, the death risk again approached the long-term trend. Our findings indicate that when internally displaced persons must adjust to situations for which appropriate coping behaviors are unknown, psychosocial stress might arise several decades after their evacuation. PMID:19771945

  1. Forced Migration and Mortality in the Very Long Term: Did Perestroika Affect Death Rates Also in Finland?

    PubMed Central

    SAARELA, JAN; FINNÄS, FJALAR

    2009-01-01

    In this article, we analyze mortality rates of Finns born in areas that were ceded to the Soviet Union after World War II and from which the entire population was evacuated. These internally displaced persons are observed during the period 1971–2004 and compared with people born in the same region but on the adjacent side of the new border. We find that in the 1970s and 1980s, the forced migrants had mortality rates that were on par with those of people in the comparison group. In the late 1980s, the mortality risk of internally displaced men increased by 20% in relation to the expected time trend. This deviation, which manifests particularly in cardiovascular mortality, coincides with perestroika and the demise of the Soviet Union, which were events that resulted in an intense debate in civil society about restitution of the ceded areas. Because state actors were reluctant to engage, the debate declined after some few years, and after the mid-1990s, the death risk again approached the long-term trend. Our findings indicate that when internally displaced persons must adjust to situations for which appropriate coping behaviors are unknown, psychosocial stress might arise several decades after their evacuation. PMID:19771945

  2. Accelerated Rates of Nitrogen Cycling and N2O Production in Salt Marsh Sediments due to Long-Term Fertilization

    NASA Astrophysics Data System (ADS)

    Peng, X.; Ji, Q.; Angell, J.; Kearns, P.; Bowen, J. L.; Ward, B. B.

    2014-12-01

    Intensified sedimentary production of nitrous oxide (N2O), one of the most potent greenhouse gases, is one of the many possible environmental consequences of elevated nitrogen (N) loading into estuarine ecosystems. This study investigates the response to over 40 years of fertilization of nitrogen removal processes in the sediments of the Great Sippewissett Marsh in Falmouth, MA. Sediment slurries were incubated (1.5 hr) with trace amounts (< 10% of ambient concentration) of 15NH4+ + 14NO3- or 15NO3- + 14NH4+. An additional parallel incubation with 15NH4+ + 14NO3- and 1 mM of allylthiourea (ATU) was included to measure rates of anaerobic ammonia oxidation (anammox). Well-homogenized slurries filled about 10% of the volume in the gas-tight incubation vials, and the rest of the volume was replaced with an O2/He (20%/80%) mixture. The production of 29N2, 44N2O and 45N2O were determined using isotope ratio mass spectrometry. The rate of total N2O production in fertilized sediments (0.89 nmol hr-1 g-1 wet weight) was 30-fold higher than in unfertilized sediments. The ratio of N2O to N2 production was also significantly higher in fertilized sediments (2.9%) than in unfertilized sediments (1.2%). This highlights the disproportionally large effect of long-term fertilization on N2O production in salt marsh sediments. The reduced oxygen level and higher ammonium concentrations in situ probably contributed to the significant rise in N2O production as a result of long-term fertilization. When detected, anammox and coupled nitrification-denitrification accounted for 10% and 14% of the total N2 production in fertilized sediments (30.5 nmol hr-1 g-1 wet weight), respectively, whereas neither was detected in unfertilized sediments. Thus these experiments indicate that N loading has important effects on multiple N cycle processes that result in N loss and N2O production.

  3. Coupling of Realistic Rate Estimates with Genomics for Assessing Contaminant Attenuation and Long-Term Plume Containment

    SciTech Connect

    Colwell, F.S.; Crawford, R.L.; Sorenson, K.

    2005-09-01

    Acceptance of monitored natural attenuation (MNA) as a preferred treatment technology saves significant site restoration costs for DOE. However, in order to be accepted MNA requires direct evidence of which processes are responsible for the contaminant loss and also the rates of the contaminant loss. Our proposal aims to: 1) provide evidence for one example of MNA, namely the disappearance of the dissolved trichloroethylene (TCE) from the Snake River Plain aquifer (SRPA) at the Idaho National Laboratory’s Test Area North (TAN) site, 2) determine the rates at which aquifer microbes can co-metabolize TCE, and 3) determine whether there are other examples of natural attenuation of chlorinated solvents occurring at DOE sites. To this end, our research has several objectives. First, we have conducted studies to characterize the microbial processes that are likely responsible for the co-metabolic destruction of TCE in the aquifer at TAN (University of Idaho and INL). Second, we are investigating realistic rates of TCE co-metabolism at the low catabolic activities typical of microorganisms existing under aquifer conditions (INL). Using the co-metabolism rate parameters derived in low-growth bioreactors, we will complete the models that predict the time until background levels of TCE are attained in the aquifer at TAN and validate the long-term stewardship of this plume. Coupled with the research on low catabolic activities of co-metabolic microbes we are determining the patterns of functional gene expression by these cells, patterns that may be used to diagnose the co-metabolic activity in the SRPA or other aquifers.

  4. Generalized discriminant analysis for congestive heart failure risk assessment based on long-term heart rate variability.

    PubMed

    Shahbazi, Fatemeh; Asl, Babak Mohammadzadeh

    2015-11-01

    The aims of this study are summarized in the following items: first, to investigate the class discrimination power of long-term heart rate variability (HRV) features for risk assessment in patients suffering from congestive heart failure (CHF); second, to introduce the most discriminative features of HRV to discriminate low risk patients (LRPs) and high risk patients (HRPs), and third, to examine the influence of feature dimension reduction in order to achieve desired accuracy of the classification. We analyzed two public Holter databases: 12 data of patients suffering from mild CHF (NYHA class I and II), labeled as LRPs and 32 data of patients suffering from severe CHF (NYHA class III and IV), labeled as HRPs. A K-nearest neighbor classifier was used to evaluate the performance of feature set in the classification. Moreover, to reduce the number of features as well as the overlap of the samples of two classes in feature space, we used generalized discriminant analysis (GDA) as a feature extraction method. By applying GDA to the discriminative nonlinear features, we achieved sensitivity and specificity of 100% having the least number of features. Finally, the results were compared with other similar conducted studies regarding the performance of feature selection procedure and classifier besides the number of features used in training. PMID:26344584

  5. Coupling of Realistic Rate Estimates with Genomics for Assessing Contaminant Attenuation and Long-Term Plume Containment

    SciTech Connect

    Colwell, F. S.; Crawford, R. L.; Sorenson, K.

    2005-06-01

    Dissolved dense nonaqueous-phase liquid plumes are persistent, widespread problems in the DOE complex. At the Idaho National Engineering and Environmental Laboratory, dissolved trichloroethylene (TCE) is disappearing from the Snake River Plain aquifer (SRPA) by natural attenuation, a finding that saves significant site restoration costs. Acceptance of monitored natural attenuation as a preferred treatment technology requires direct evidence of the processes and rates of the degradation. Our proposal aims to provide that evidence for one such site by testing two hypotheses. First, we believe that realistic values for in situ rates of TCE cometabolism can be obtained by sustaining the putative microorganisms at the low catabolic activities consistent with aquifer conditions. Second, the patterns of functional gene expression evident in these communities under starvation conditions while carrying out TCE cometabolism can be used to diagnose the cometabolic activity in the aquifer itself. Using the cometabolism rate parameters derived in low-growth bioreactors, we will complete the models that predict the time until background levels of TCE are attained at this location and validate the long-term stewardship of this plume. Realistic terms for cometabolism of TCE will provide marked improvements in DOE's ability to predict and monitor natural attenuation of chlorinated organics at other sites, increase the acceptability of this solution, and provide significant economic and health benefits through this noninvasive remediation strategy. Finally, this project aims to derive valuable genomic information about the functional attributes of subsurface microbial communities upon which DOE must depend to resolve some of its most difficult contamination issues.

  6. Evaluation of Neural Response Telemetry (NRT™) with focus on long-term rate adaptation over a wide range of stimulation rates.

    PubMed

    Huarte, Alicia; Ramos, Angel; Morera, Constantino; Garcia-Ibáñez, Luis; Battmer, Rolf; Dillier, Norbert; Wesarg, Thomas; Müller-Deile, Joachim; Hey, Mattias; Offeciers, Erwin; von Wallenberg, Ernst; Coudert, Chrystelle; Killian, Matthijs

    2014-05-01

    Custom Sound EP™ (CSEP) is an advanced flexible software tool dedicated to recording of electrically evoked compound action potentials (ECAPs) in Nucleus® recipients using Neural Response Telemetry™ (NRT™). European multi-centre studies of the Freedom™ cochlear implant system confirmed that CSEP offers tools to effectively record ECAP thresholds, amplitude growth functions, recovery functions, spread of excitation functions, and rate adaptation functions and an automated algorithm (AutoNRT™) to measure threshold profiles. This paper reports on rate adaptation measurements. Rate adaptation of ECAP amplitudes can successfully be measured up to rates of 495 pulses per second (pps) by repeating conventional ECAP measurements and over a wide range of rates up to 8000 pps using the masked response extraction technique. Rate adaptation did not show a predictable relationship with speech perception and coding strategy channel rate preference. The masked response extraction method offers opportunities to study long-term rate adaptation with well-defined and controlled stimulation paradigms. PMID:24559068

  7. Determining the long-term slip rate of the Pernicana Fault System, Mt. Etna, to improve earthquake forecast modelling

    NASA Astrophysics Data System (ADS)

    D'Amato, Davide; Pace, Bruno; Di Nicola, Luigia; Stuart, Finlay M.; Barfod, Dan; Branca, Stefano; Azzaro, Raffaele; Visini, Francesco

    2013-04-01

    The Pernicana fault system (PFS) is a complex active tectonic systems located in the NE sector of Mt. Etna. It represents the northern boundary of the sliding side of the volcano and plays an important role in the dynamics of the eastern flank. Several historic and recent earthquakes have occurred close to this structure with coseismic surface faulting and damage (e.g. 02/04/2010 earthquake, Mw = 4.2). The PFS is transtensive, characterised by complex of en echelon segments with a N 110° overall direction. The dip-slip component decreases to the East accompanied with a decreasing of seismic activity. The eastern-most segment is characterised by left aseismic creeping strike-slip motion. The aim of this work is to constrain to constrain the long-term history of the PFS using 40Ar/39Ar and cosmogenic 3He ages of lava flows that are cut by the PFS in order to better understand the fault behaviour and improve the prediction of earthquake occurrence. We will present the first 3D shape of the PFS based on a network of detailed topographic profiles, to better constrain the variability of the fault scarp along strike and so the kinematics of the structure. In situ cosmogenic 3He exposure ages of two faulted lava flows from the central sector of PFS are used to determine the slip rate. Flow ages (1157 ± 230 yr and 1088 ± 96 yr) are combined with fault scarp heights to calculate an average vertical slip rate of about 11 mm/year over the last 1,000 years for the central section of the PFS. This rate is close to the rate determined from historical and geodetic data (displacement of antropic manufact and geodetic levelling), covering the last 20 years. It suggests that the slip-rates have not changed significantly in the last 1,000 years. The new fault geometry and slip rate data have been used to realise a kinematic and strain model of the PFS, in order to distinguish the vertical and the horizontal slip rate components and to model the tectonic and volcanic strain fields

  8. Long-term background denudation rates of southern and southeastern Brazilian watersheds estimated with cosmogenic 10Be

    NASA Astrophysics Data System (ADS)

    Sosa Gonzalez, Veronica; Bierman, Paul R.; Fernandes, Nelson F.; Rood, Dylan H.

    2016-09-01

    In comparison to humid temperate regions of the Northern Hemisphere, less is known about the long-term (millennial scale) background rates of erosion in Southern Hemisphere tropical watersheds. In order to better understand the rate at which watersheds in southern and southeastern Brazil erode, and the relationship of that erosion to climate and landscape characteristics, we made new measurements of in situ produced 10Be in river sediments and we compiled all extant measurements from this part of the country. New data from 14 watersheds in the states of Santa Catarina (n = 7) and Rio de Janeiro (n = 7) show that erosion rates vary there from 13 to 90 m/My (mean = 32 m/My; median = 23 m/My) and that the difference between erosion rates of basins we sampled in the two states is not significant. Sampled basin area ranges between 3 and 14,987 km2, mean basin elevation between 235 and 1606 m, and mean basin slope between 11 and 29°. Basins sampled in Rio de Janeiro, including three that drain the Serra do Mar escarpment, have an average basin slope of 19°, whereas the average slope for the Santa Catarina basins is 14°. Mean basin slope (R2 = 0.73) and annual precipitation (R2 = 0.57) are most strongly correlated with erosion in the basins we studied. At three sites where we sampled river sand and cobbles, the 10Be concentration in river sand was greater than in the cobbles, suggesting that these grain sizes are sourced from different parts of the landscape. Compiling all cosmogenic 10Be-derived erosion rates previously published for southern and southeastern Brazil watersheds to date (n = 76) with our 14 sampled basins, we find that regional erosion rates (though low) are higher than those of watersheds also located on other passive margins including Namibia and the southeastern North America. Brazilian basins erode at a pace similar to escarpments in southeastern North America. Erosion rates in southern and southeastern Brazil are directly and positively related to

  9. Sensitivity of Decomposition Rates and Long-term Carbon Sequestration to Modeled Disturbance Scenarios: Implications for National Monitoring Efforts

    NASA Astrophysics Data System (ADS)

    O'Neill, K. P.; Harden, J. W.

    2002-12-01

    Soil systems are central to carbon, water, and nutrient cycles and play a key role in regulating CO{2} exchange in terrestrial systems. While recent advances have been made for measuring plant production, the mechanisms that control the loss of carbon from land are masked by difficulties in detecting and scaling belowground processes. National and international reporting requirements have placed increased emphasis on the development of spatially explicit soil carbon inventories based on monitoring changes in major soil reservoirs. Although this inventory approach provides critical baseline information, the ecological significance of this soil carbon ultimately depends upon the level of chemical and physical protection, the response of the soil system to disturbance, and the temporal and spatial scales of interest. In this paper, we model the sensitivity of carbon storage estimates to differing assumptions of decomposition and disturbance response using data from the USDA Forest Service's Forest Inventory and Analysis (FIA) Program. The FIA soil indicator program represents the only nationally consistent source of forest soil monitoring data in the United States and forms the basis for national reporting on the Montreal Process Criteria and Indicators of Sustainable Management. A mass-balance model of long term soil carbon dynamics is used to address the following questions: (1) how sensitive are soil carbon inventories to current assumptions of inputs, turnover, and disturbance response; (2) which soil processes have the greatest influence on C storage over the time scales relevant to land use policies and how can we best monitor these processes; (3) what are the critical data gaps limiting the use of inventory data in regional and global carbon models.

  10. Future rates of sea-level rise from long-term coupled climate-ice sheet projections

    NASA Astrophysics Data System (ADS)

    Goelzer, Heiko; Huybrechts, Philippe; Loutre, Marie-France; Fichefet, Thierry

    2015-04-01

    Global mean sea level rose at an average rate of ~3.1 mm yr-1 since the early 1990s and is projected to rise between 0.28 and 0.98 m until year 2100, strongly depending on the assumed anthropogenic forcing scenario (IPCC AR5). This global rise in sea level is a combination of contributions from ocean thermal expansion, glaciers and small ice caps, from the Greenland and Antarctic ice sheets and changes in land water storage. Except for the latter, all components are expected to contribute to further sea-level rise well beyond the end of this century due to the long residence time of CO2 in the atmosphere. In the present study we present results from long-term future sea-level change experiments over 1000 years with the Earth system model of intermediate complexity LOVECLIM version 1.3 forced by four extended RCP scenarios. The model includes fully coupled three-dimensional thermomechanical models of the Greenland and Antarctic ice sheets, a global glacier melt algorithm to account for the response of mountain glaciers and small ice caps, and a diagnostic for oceanic thermal expansion. A range of the model's sensitivity to greenhouse warming was sampled by systematic parameter variations leading to an ensemble of model versions that simulate the present-day climate consistent with observations, while producing contrasted results for the future period. We analyse sea-level rates of change for all components over the course of the third millennium for the entire ensemble of model versions and forcing scenarios.

  11. Long-Term Care

    MedlinePlus

    ... this page please turn Javascript on. Long-Term Care What Is Long-Term Care? Long-term care involves a variety of services ... the Escape (Esc) button on your keyboard.) Most Care Provided at Home Long-term care is provided ...

  12. Coupling of Realistic Rate Estimates with Genomics for Assessing Contaminant Attenuation and Long-Term Plume Containment

    SciTech Connect

    Colwell, F. S.; Crawford, R. L.; Sorenson, K.

    2005-09-01

    Acceptance of monitored natural attenuation (MNA) as a preferred treatment technology saves significant site restoration costs for DOE. However, in order to be accepted MNA requires direct evidence of which processes are responsible for the contaminant loss and also the rates of the contaminant loss. Our proposal aims to: 1) provide evidence for one example of MNA, namely the disappearance of the dissolved trichloroethylene (TCE) from the Snake River Plain aquifer (SRPA) at the Idaho National Laboratory’s Test Area North (TAN) site, 2) determine the rates at which aquifer microbes can co-metabolize TCE, and 3) determine whether there are other examples of natural attenuation of chlorinated solvents occurring at DOE sites. To this end, our research has several objectives. First, we have conducted studies to characterize the microbial processes that are likely responsible for the co-metabolic destruction of TCE in the aquifer at TAN (University of Idaho and INL). Second, we are investigating realistic rates of TCE co-metabolism at the low catabolic activities typical of microorganisms existing under aquifer conditions (INL). Using the co-metabolism rate parameters derived in low-growth bioreactors, we will complete the models that predict the time until background levels of TCE are attained in the aquifer at TAN and validate the long-term stewardship of this plume. Coupled with the research on low catabolic activities of co-metabolic microbes we are determining the patterns of functional gene expression by these cells, patterns that may be used to diagnose the co-metabolic activity in the SRPA or other aquifers. Third, we have systematically considered the aquifer contaminants at different locations in plumes at other DOE sites in order to determine whether MNA is a broadly applicable remediation strategy for chlorinated hydrocarbons (North Wind Inc.). Realistic terms for co-metabolism of TCE will provide marked improvements in DOE’s ability to predict and

  13. The impairment of true glomerular filtration rate in long-term cyclosporine-treated pediatric allograft recipients

    SciTech Connect

    McDiarmid, S.V.; Ettenger, R.B.; Hawkins, R.A.; Senguttvan, P.; Busuttil, R.W.; Vargas, J.; Berquist, W.E.; Ament, M.E.

    1990-01-01

    We performed indium-111-DTPA plasma clearance studies in 61 pediatric kidney and liver recipients treated with cyclosporine to compare true glomerular filtration rate with calculated GFR (cGFR). The mean true GFR of 61.9 +/- 36.6 ml/min/1.73 m2 indicated renal impairment. The mean cGFR of 85.2 +/- 22.4 ml/min/1.73 m2 was significantly higher (P less than 0.001), and overestimated GFR by 38%. cGFR alone did not accurately reflect the degree of renal dysfunction. A group of 48 pediatric orthotopic liver transplant recipients was studied in more detail: 73% of these patients had a true GFR less than 70 ml/min/1.73 m2, while 85% had a true GFR below 90 ml/min/1.73 m2, the lower limit for normal GFR in children. The mean true GFR for patients treated more than 24 months with CsA was lower (P = 0.02) than patients treated with CsA for 12 to 24 months. OLT patients with normal true GFR (greater than 90 ml/min/1.73 m2) had significantly lower plasma CsA levels, and 50% of patients with a true GFR less than or equal to 50 ml/min/1.73 m2 had hypertension. There was no effect on true GFR of age, liver function, azathioprine use, or peritransplant treatment with other nephrotoxic drugs. We conclude that true GFR is significantly impaired in long-term CsA-treated allograft pediatric recipients. Calculations of GFR underestimate the degree of renal dysfunction. As patients treated greater than 24 months had the lowest true GFRs, the fall in GFR may be progressive.

  14. Long-term and Short-term Vertical Deformation Rates across the Forearc in the Central Mexican Subduction Zone

    NASA Astrophysics Data System (ADS)

    Ramirez-Herrera, M. T.; Gaidzik, K.; Forman, S. L.; Kostoglodov, V.; Burgmann, R.

    2015-12-01

    Spatial scales of the earthquake cycle, from rapid deformation associated with earthquake rupture to slow deformation associated with interseismic and transient slow-slip behavior, span from fractions of a meter to thousands of kilometers (plate boundaries). Similarly, temporal scales range from seconds during an earthquake rupture to thousands of years of strain accumulation between earthquakes. The complexity of the multiple physical processes operating over this vast range of scales and the limited coverage of observations leads most scientists to focus on a narrow space-time window to isolate just one or a few process. We discuss here preliminary results on the vertical crustal deformation associated with both slow and rapid crustal deformation along a profile across the forearc region of the central Mexican subduction zone on the Guerrero sector, where the Cocos plate underthrusts the North American plate. This sector of the subduction zone is characterized by a particular slab geometry (with zones of rapid bending-unbending of the slab), irregular distributed seismicity, exceptionally large slow slip events (SSE) and non-volcanic tremors (NVT). We used the river network and geomorphic features of the Papagayo River to assess Quaternary crustal deformation. The Papagayo drainage network is strongly controlled by Late Cenozoic tectonic, Holocene and recent earthquake cycle processes. This is particularly true for the southern section of the drainage basin; from the dam in La Venta to the river mouth, where W-E structures commonly offset the course of the main river. River terraces occur along the course of the river at different elevations. We measured the height of a series of terraces and obtained OSL ages on quartz extracts to determine long-term rates of deformation. Finally, we discuss associations of the topography and river characteristics with the Cocos slab geometry, slow earthquakes, crustal deformation, and interseismic deformation.

  15. FEASIBILITY OF DOSE ADJUSTMENT BASED ON DIFFERENCE IN LONG-TERM CLEARANCE RATES OF INHALED PARTICULATE MATTER IN HUMANS AND LABORATORY ANIMALS

    EPA Science Inventory

    Long-term pulmonary clearance rates were evaluated for several laboratory animal species, dogs, and humans to determine if differences among species exist, and if so, the adequacy of the data for dose adjustment. Within each species, large variations in clearance rates were seen,...

  16. A study of the long term impact of an inquiry-based science program on student's attitudes towards science and interest in science careers

    NASA Astrophysics Data System (ADS)

    Gibson, Helen Lussier

    One reason science enrichment programs were created was to address the underrepresentation of women and minorities in science. These programs were designed to increase underrepresented groups' interest in science and science careers. One attempt to increase students' interest in science was the Summer Science Exploration Program (SSEP). The SSEP was a two week, inquiry-based summer science camp offered by Hampshire College for students entering grades seven and eight. Students who participated were from three neighboring school districts in Western Massachusetts. The goal of the program was to stimulate greater interest in science and scientific careers among middle school students, in particular among females and students of color. A review of the literature of inquiry-based science programs revealed that the effect of inquiry-based programs on students' attitudes towards science is typically investigated shortly after the end of the treatment period. The findings from this study contribute to our understanding of the long-term impact of inquiry-based science enrichment programs on students' attitude towards science and their interest in science careers. The data collected consisted of quantitative survey data as well as qualitative data through case studies of selected participants from the sample population. This study was guided by the following questions: (1) What was the nature and extent of the impact of the Summer Science Exploration Program (SSEP) on students' attitudes towards science and interest in science careers, in particular among females and students of color? (2) What factors, if any, other than participation in SSEP impacted students' attitude towards science and interest in scientific careers? (3) In what other ways, if any, did the participants benefit from the program? Conclusions drawn from the data indicate that SSEP helped participants maintain a high level of interest in science. In contrast, students who applied but were not accepted

  17. Changes in long-term no-till corn growth and yield under different rates of stover mulch

    SciTech Connect

    Blanco-Canqui, Dr. Humberto; Lal, Dr. Rattan; Post, Wilfred M; Owens, Lloyd

    2006-09-01

    Received for publication January 4, 2006. Removal of corn (Zea mays L.) stover for biofuel production may affect crop yields by altering soil properties. A partial stover removal may be feasible, but information on appropriate rates of removal is unavailable. We assessed the short-term impacts of stover management on long-term no-till (NT) continuous corn grown on a Rayne silt loam (fine loamy, mixed, active, mesic Typic Hapludults) at Coshocton, Hoytville clay loam (fine, illitic, mesic Mollic Epiaqualfs) at Hoytville, and Celina silt loam (fine, mixed, active, mesic Aquic Hapludalfs) at South Charleston in Ohio, and predicted corn yield from soil properties using principal component analysis (PCA). The study was conducted in 2005 on the ongoing experiments started in May 2004 under 0 (T0), 25 (T25), 50 (T50), 75 (T75), 100 (T100), and 200 (T200)% of stover corresponding to 0, 1.25, 2.50, 3.75, 5.00, and 10.00 Mg ha-1 of stover, respectively. Stover removal promoted early emergence and rapid seedling growth (P < 0.01). Early-emerging plants grew taller than late-emerging plants up to about 50 d, and then the heights reversed at Coshocton and were comparable at other two sites. Stover management affected corn yield only at the Coshocton site where average grain and stover yields in the T200, T100, T75, and T50 (10.8 and 10.3 Mg ha-1) were higher than those in the T0 and T25 treatments (8.5 and 6.5 Mg ha-1) (P < 0.01), showing that stover removal at rates as low as 50% (2.5 Mg ha-1) decreased crop yields. Soil properties explained 71% of the variability in grain yield and 33% of the variability in stover yield for the Coshocton site. Seventeen months after the start of the experiment, effects of stover management on corn yield and soil properties were site-specific.

  18. Long-term erosion rate measurements in gypsum caves of Sorbas (SE Spain) by the Micro-Erosion Meter method

    NASA Astrophysics Data System (ADS)

    Sanna, Laura; De Waele, Jo; Calaforra, José Maria; Forti, Paolo

    2015-01-01

    The present work deals with the results of long-term micro-erosion measurements in the most important gypsum cave of Spain, the Cueva del Agua (Sorbas, Almeria, SE Spain). Nineteen MEM stations were positioned in 1992 in a wide range of morphological and environmental settings (gypsum floors and walls, carbonate speleothems, dry conduits and vadose passages) inside and outside the cave, on gypsum and carbonate bedrocks and exposed to variable degree of humidity, different air flow and hydrodynamic conditions. Four different sets of stations have been investigated: (1) the main cave entrance (Las Viñicas spring); (2) the main river passage; (3) the abandoned Laboratory tunnel; and (4) the external gypsum surface. Data over a period of about 18 years are available. The average lowering rates vary from 0.014 to 0.016 mm yr- 1 near the main entrance and in the Laboratory tunnel, to 0.022 mm - 1 on gypsum floors and 0.028 mm yr- 1 on carbonate flowstones. The denudation data from the external gypsum stations are quite regular with a rate of 0.170 mm yr- 1. The observations allowed the collecting of important information concerning the feeding of the karst aquifer not only by infiltrating rainwater, but under present climate conditions also by water condensation of moist air flow. This contribution to the overall karst processes in the Cueva del Agua basin represents over 20% of the total chemical dissolution of the karst area and more than 50% of the speleogenetically removed gypsum in the cave system, thus representing all but a secondary role in speleogenesis. Condensation-corrosion is most active along the medium walls, being slower at the roof and almost absent close to the floor. This creates typical corrosion morphologies such as cupola, while gypsum flowers develop where evaporation dominates. This approach also shows quantitatively the morphological implications of condensation-corrosion processes in gypsum karst systems in arid zones, responsible for an

  19. Possible long-term decline in impact rates. 2. Lunar impact-melt data regarding impact history

    NASA Astrophysics Data System (ADS)

    Hartmann, William K.; Quantin, Cathy; Mangold, Nicolas

    2007-01-01

    Crater counts at lunar landing sites with measured ages establish a steep decline in cratering rate during the period ˜3.8 to ˜3.1 Gyr ago. Most models of the time dependence suggest a roughly constant impact rate (within factor ˜2) after about 3 Gyr ago, but are based on sparse data. Recent dating of impact melts from lunar meteorites, and Apollo glass spherules, clarifies impact rates from ˜3.2 to ˜2 Gyr ago or less. Taken together, these data suggest a decline with roughly 700 Myr half-life around 3 Gyr ago, and a slower decline after that, dropping by a factor ˜3 from about ˜2.3 Gyr ago until the present. Planetary cratering involved several phases with different time behaviors: (1) rapid sweep-up of most primordial planetesimals into planets in the first hundred Myr, (2) possible later effects of giant planet migration with enhanced cratering, (3) longer term sweep-up of leftover planetesimals, and finally (4) the present long-term "leakage" of asteroids from reservoirs such as the main asteroid belt and Kuiper belt. In addition, at any given point on the Moon, a pattern of "spikes" (sharp maxima of relatively narrow time width) will appear in the production rate of smaller craters (≲500 m?), not only from secondary debris from large primary lunar impacts at various distances from the point in question, but also from asteroid breakups dotted through Solar System history. The pattern of spikes varies according to type of sample being measured (i.e., glass spherules vs impact melts). For example, several data sets show an impact rate spike ˜470 Myr ago associated with the asteroid belt collision that produced the L chondrites (see Section 3.6 below). Such spikes should be less prominent in the production record of craters of D≳ few km. These phenomena affect estimates of planetary surfaces ages from crater counts, as discussed in a companion paper [Quantin, C., Mangold, N., Hartmann, W.K., Allemand, P., 2007. Icarus 186, 1-10]. Fewer impact melts and

  20. 7 CFR 4279.125 - Interest rates.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... applicant and may be either fixed or variable as long as it is a legal rate. Interest rates will not be more... market and pass interest-rate savings on to the borrower. (a) A variable interest rate agreed to by the.... The variable interest rate may be adjusted at different intervals during the term of the loan, but...

  1. 7 CFR 1980.320 - Interest rate.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 14 2010-01-01 2009-01-01 true Interest rate. 1980.320 Section 1980.320 Agriculture... REGULATIONS (CONTINUED) GENERAL Rural Housing Loans § 1980.320 Interest rate. The interest rate must not... interest rate over the life of the loan. The rate shall be agreed upon by the borrower and the Lender...

  2. 7 CFR 4279.125 - Interest rates.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... applicant and may be either fixed or variable as long as it is a legal rate. Interest rates will not be more... market and pass interest-rate savings on to the borrower. (a) A variable interest rate agreed to by the.... The variable interest rate may be adjusted at different intervals during the term of the loan, but...

  3. Rates, causes, and dynamic of long-term landscape evolution of the South Atlantic "passive continental margin", Brazil and Namibia, as revealed by thermo-kinematic numerical modeling.

    NASA Astrophysics Data System (ADS)

    Christian, Stippich; Anton, Glasmacher Ulrich; Peter, Christian, Hackspacher

    2014-05-01

    The aim of the research is to quantify the long-term landscape evolution of the South Atlantic passive continental margin (SAPCM) in SE-Brazil and NW-Namibia. Excellent onshore outcrop conditions and complete rift to post-rift archives between Sao Paulo and Porto Alegre and in the transition from Namibia to Angola (onshore Walvis ridge) allow a high precision quantification of exhumation, and uplift rates, influencing physical parameters, long-term acting forces, and process-response systems. Research will integrate the published and partly published thermochronological data from Brazil and Namibia, and test lately published new concepts on causes of long-term landscape evolution at rifted margins. The climate-continental margin-mantle coupled process-response system is caused by the interaction between endogenous and exogenous forces, which are related to the mantle-process driven rift - drift - passive continental margin evolution of the South Atlantic, and the climate change since the Early/Late Cretaceous climate maximum. Special emphasis will be given to the influence of long-living transform faults such as the Florianopolis Fracture Zone (FFZ) on the long-term topography evolution of the SAPCM's. A long-term landscape evolution model with process rates will be achieved by thermo-kinematic 3-D modeling (software code PECUBE and FastCape). Testing model solutions obtained for a multidimensional parameter space against the real thermochronological and geomorphological data set, the most likely combinations of parameter rates, and values can be constrained. The data and models will allow separating the exogenous and endogenous forces and their process rates.

  4. 27 CFR 70.93 - Interest rate.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Interest rate. 70.93... Excise and Special (Occupational) Tax Interest § 70.93 Interest rate. (a) In general. The interest rate... application of daily compounding in determining interest accruing after December 31, 1982. Because...

  5. 27 CFR 70.93 - Interest rate.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2011-04-01 2011-04-01 false Interest rate. 70.93... Excise and Special (Occupational) Tax Interest § 70.93 Interest rate. (a) In general. The interest rate... application of daily compounding in determining interest accruing after December 31, 1982. Because...

  6. Gray matter volume is associated with rate of subsequent skill learning after a long term training intervention.

    PubMed

    Sampaio-Baptista, Cassandra; Scholz, Jan; Jenkinson, Mark; Thomas, Adam G; Filippini, Nicola; Smit, Gabrielle; Douaud, Gwenaëlle; Johansen-Berg, Heidi

    2014-08-01

    The ability to predict learning performance from brain imaging data has implications for selecting individuals for training or rehabilitation interventions. Here, we used structural MRI to test whether baseline variations in gray matter (GM) volume correlated with subsequent performance after a long-term training of a complex whole-body task. 44 naïve participants were scanned before undertaking daily juggling practice for 6weeks, following either a high intensity or a low intensity training regime. To assess performance across the training period participants' practice sessions were filmed. Greater GM volume in medial occipito-parietal areas at baseline correlated with steeper learning slopes. We also tested whether practice time or performance outcomes modulated the degree of structural brain change detected between the baseline scan and additional scans performed immediately after training and following a further 4weeks without training. Participants with better performance had higher increases in GM volume during the period following training (i.e., between scans 2 and 3) in dorsal parietal cortex and M1. When contrasting brain changes between the practice intensity groups, we did not find any straightforward effects of practice time though practice modulated the relationship between performance and GM volume change in dorsolateral prefrontal cortex. These results suggest that practice time and performance modulate the degree of structural brain change evoked by long-term training regimes. PMID:24680712

  7. A NEW PARADIGM FOR GAMMA-RAY BURSTS: LONG-TERM ACCRETION RATE MODULATION BY AN EXTERNAL ACCRETION DISK

    SciTech Connect

    Cannizzo, J. K. E-mail: gehrels@milkyway.gsfc.nasa.gov

    2009-08-01

    We present a new way of looking at the very long-term evolution of gamma-ray bursts (GRBs) in which the disk of material surrounding the putative black hole powering the GRB jet modulates the mass flow, and hence the efficacy of the process that extracts rotational energy from the black hole and inner accretion disk. The pre-Swift paradigm of achromatic, shallow-to-steep 'breaks' in the long-term GRB light curves has not been borne out by detailed Swift data amassed in the past several years. We argue that, given the initial existence of a fall-back disk near the progenitor, an unavoidable consequence will be the formation of an 'external disk' whose outer edge continually moves to larger radii due to angular momentum transport and lack of a confining torque. The mass reservoir at large radii moves outward with time and gives a natural power-law decay to the GRB light curves. In this model, the different canonical power-law decay segments in the GRB identified by Zhang et al. and Nousek et al. represent different physical states of the accretion disk. We identify a physical disk state with each power-law segment.

  8. Gray matter volume is associated with rate of subsequent skill learning after a long term training intervention

    PubMed Central

    Sampaio-Baptista, Cassandra; Scholz, Jan; Jenkinson, Mark; Thomas, Adam G.; Filippini, Nicola; Smit, Gabrielle; Douaud, Gwenaëlle; Johansen-Berg, Heidi

    2014-01-01

    The ability to predict learning performance from brain imaging data has implications for selecting individuals for training or rehabilitation interventions. Here, we used structural MRI to test whether baseline variations in gray matter (GM) volume correlated with subsequent performance after a long-term training of a complex whole-body task. 44 naïve participants were scanned before undertaking daily juggling practice for 6 weeks, following either a high intensity or a low intensity training regime. To assess performance across the training period participants' practice sessions were filmed. Greater GM volume in medial occipito-parietal areas at baseline correlated with steeper learning slopes. We also tested whether practice time or performance outcomes modulated the degree of structural brain change detected between the baseline scan and additional scans performed immediately after training and following a further 4 weeks without training. Participants with better performance had higher increases in GM volume during the period following training (i.e., between scans 2 and 3) in dorsal parietal cortex and M1. When contrasting brain changes between the practice intensity groups, we did not find any straightforward effects of practice time though practice modulated the relationship between performance and GM volume change in dorsolateral prefrontal cortex. These results suggest that practice time and performance modulate the degree of structural brain change evoked by long-term training regimes. PMID:24680712

  9. A New Paradigm for Gamma Ray Bursts: Long Term Accretion Rate Modulation by an External Accretion Disk

    NASA Technical Reports Server (NTRS)

    Cannizzo, John; Gehrels, Neil

    2009-01-01

    We present a new way of looking at the very long term evolution of GRBs in which the disk of material surrounding the putative black hole powering the GRB jet modulates the mass flow, and hence the efficacy of the process that extracts rotational energy from the black hole and inner accretion disk. The pre-Swift paradigm of achromatic, shallow-to-steep "breaks" in the long term GRB light curves has not been borne out by detailed Swift data amassed in the past several years. We argue that, given the initial existence of a fall-back disk near the progenitor, an unavoidable consequence will be the formation of an "external disk" whose outer edge continually moves to larger radii due to angular momentum transport and lack of a confining torque. The mass reservoir at large radii moves outward with time and gives a natural power law decay to the GRB light curves. In this model, the different canonical power law decay segments in the GRB identified by Zhang et al. and Nousek et al. represent different physical states of the accretion disk. We identify a physical disk state with each power law segment.

  10. 7 CFR 4274.325 - Interest rates.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Interest rates. 4274.325 Section 4274.325 Agriculture... (IRP) § 4274.325 Interest rates. (a) Loans made by the Agency pursuant to this subpart shall bear interest at a fixed rate of 1 percent per annum over the term of the loan. (b) Interest rates charged...

  11. Constraints on long-term carbon-climate feedbacks from spatially resolved CO2 growth rate fluctuations linked to temperature and precipitation

    NASA Astrophysics Data System (ADS)

    Keppel-Aleks, G.; Hoffman, F. M.

    2014-12-01

    Feedbacks between the global carbon cycle and climate represent one of the largest uncertainties in climate prediction. A promising method for reducing uncertainty in predictions of carbon-climate feedbacks is based on identifying an "emergent constraint" that leverages correlations between mechanistically linked long-term feedbacks and short-term variations within the model ensemble. By applying contemporary observations to evaluate model skill in simulating short-term variations, we may be able to better assess the probability of simulated long-term feedbacks. We probed the constraint on long-term terrestrial carbon stocks provided by climate-driven fluctuations in the atmospheric CO2 growth rate at contemporary timescales. We considered the impact of both temperature and precipitation anomalies on terrestrial ecosystem exchange and further separated the direct influence of fire where possible. When we explicitly considered the role of atmospheric transport in smoothing the imprint of climate-driven flux anomalies on atmospheric CO2 patterns, we found that the extent of temporal averaging of both the observations and ESM output leads to estimates for the long-term climate sensitivity of tropical land carbon storage that are different by a factor of two. In the context of these results, we discuss strategies for applying emergent constraints for benchmarking biogeochemical feedbacks in ESMs. Specifically, our results underscore the importance of selecting appropriate observational benchmarks and, for future model intercomparison projects, outputting fields that most closely correspond to available observational datasets.

  12. 7 CFR 1980.423 - Interest rates.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... effect a permanent reduction in the interest rate of their B&I guaranteed loan at any time during the... interest rate for insured loans will be the rate in effect at the time the loan is approved or at the time... approving the lender's interest rate, the rate at which guaranteed loans are being sold or traded in...

  13. 76 FR 59767 - Interest Rates; Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-27

    ... publishes an interest rate called the optional ``peg'' rate (13 CFR 120.214) on a quarterly basis. This rate... direct loan. This rate may be used as a base rate for guaranteed fluctuating interest rate SBA loans. This rate will be 3.125 (3\\1/8\\) percent for the October-December quarter of FY 2012. Pursuant to...

  14. Height of faceted spurs, a proxy for determining long-term throw rates on normal faults: Evidence from the North Baikal Rift System, Siberia

    NASA Astrophysics Data System (ADS)

    Petit, Carole; Meyer, Bertrand; Gunnell, Yanni; Jolivet, Marc; San'kov, Vladimir; Strak, Vincent; Gonga-Saholiariliva, Nahossio

    2010-05-01

    We present new results on the long-term throw rates of active normal faults in the North Baikal Rift (NBR), eastern Siberia, based on a statistical analysis of triangular faceted scarps. Faceted spurs or triangular facets are morphologic features frequently observed along normal fault scarps, and result from the progressive denudation and incision of the footwall during fault activity. Fault-bounded ridges in the NBR display such typical morphologies with several contiguous facets separated by fault-perpendicular catchments. Over a range of 20 fault segments analyzed, triangular facet heights vary from ~200 to >900 m. As fault scarps have been developing under similar long-term climatic conditions, we infer that the scatter in mean facet height arises from long-term differences in fault throw rate. We compare the morphology of NBR facets with results obtained in a previously published numerical model of facet growth, which predicts that the mean height of triangular facets is proportional to the fault throw rate. Using facet height as an input, model results provide estimates of the long-term fault throw rates in the NBR. These vary between 0.2 and 1.2 mm/yr. The throw rates are then compared with the cumulated throw, which has been constrained by geophysical and stratigraphic data in the basins. This provides an estimate of the age of fault and basin initiation. We show that the modern stage of basin development started circa 3 Myr ago, except for the North Baikal basin (~ 8 Ma). Our results also suggest that a proportion of the observed throw is inherited from an earlier tectonic stage.

  15. A Discordancy Between Short-Term Sedimentation Rate Using Pb-210, Cs-137 and Pu and Long-Term Sedimentation Rate Using C-14

    NASA Astrophysics Data System (ADS)

    Baskaran, M.; Filley, T. R.; Bianchi, T. S.; Freeman, K. H.; Hatcher, P. G.

    2005-12-01

    Short-lived radionuclides (210Pb, 137Cs, etc) have been successfully utilized to obtain sedimentation rates in freshwater and coastal marine environments over the past 3 decades. Combined use of 210Pb and Pu enable to delineate sedimentation from sediment mixing. However independent validation of short-term accumulation rates using other long-lived isotopes, such as 14C are very limited. We collected a sediment core from a sinkhole lake, Mud Lake, Florida, USA and analyzed it for 210Pb, 137Cs, 239,240Pu and 14C. The sediment inventories of 137Cs, and 239,240Pu are comparable to the regional global fallout values while 210Pb inventory is comparable to the value reported for this region. A plot of depth against 14C age yields an intercept value of 1070 yrs, indicating a reservoir correction age of 1070 yrs. Most of the data points fall either on the straight line or close to the line possibly suggesting that the relative proportion of fossil carbon had remained constant throughout the core. Due to sediment compaction, a comparison of linear sedimentation rate obtained using short-lived radionuclides with those 14C could yield considerable difference and hence we compared the mass accumulation rates obtained from these isotopes. The 210Pbxs-based sediment mass accumulation rate of 17 mg cm-2 y-1, is almost a factor of 3 higher than that obtained using 14C -derived mass accumulation rate of 6 mg cm-2 y-1. The peak fallout of Pu is well preserved in the lake core suggesting relatively minimum sediment mixing. The factors that could cause this discordancy between the long-term and short-term mass accumulation rates will be discussed.

  16. 38 CFR 36.4312 - Interest rates.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... result in a change in either direction of more than one percentage point from the interest rate in effect... such loans either bear interest at a rate that is agreed upon by the veteran and the lender, or bear interest at a rate not in excess of a rate established by the Secretary. The Secretary may, from time...

  17. 38 CFR 36.4312 - Interest rates.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... result in a change in either direction of more than one percentage point from the interest rate in effect... such loans either bear interest at a rate that is agreed upon by the veteran and the lender, or bear interest at a rate not in excess of a rate established by the Secretary. The Secretary may, from time...

  18. 12 CFR 614.4155 - Interest rates.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 6 2011-01-01 2011-01-01 false Interest rates. 614.4155 Section 614.4155 Banks... Policies for Banks and Associations § 614.4155 Interest rates. Loans made by each bank and direct lender association shall bear interest at a rate or rates as may be determined by the institution board. The...

  19. 12 CFR 614.4155 - Interest rates.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Interest rates. 614.4155 Section 614.4155 Banks... Policies for Banks and Associations § 614.4155 Interest rates. Loans made by each bank and direct lender association shall bear interest at a rate or rates as may be determined by the institution board. The...

  20. Long Term Sugarcane Crop Residue Retention Offers Limited Potential to Reduce Nitrogen Fertilizer Rates in Australian Wet Tropical Environments

    PubMed Central

    Meier, Elizabeth A.; Thorburn, Peter J.

    2016-01-01

    The warming of world climate systems is driving interest in the mitigation of greenhouse gas (GHG) emissions. In the agricultural sector, practices that mitigate GHG emissions include those that (1) reduce emissions [e.g., those that reduce nitrous oxide (N2O) emissions by avoiding excess nitrogen (N) fertilizer application], and (2) increase soil organic carbon (SOC) stocks (e.g., by retaining instead of burning crop residues). Sugarcane is a globally important crop that can have substantial inputs of N fertilizer and which produces large amounts of crop residues (‘trash’). Management of N fertilizer and trash affects soil carbon and nitrogen cycling, and hence GHG emissions. Trash has historically been burned at harvest, but increasingly is being retained on the soil surface as a ‘trash blanket’ in many countries. The potential for trash retention to alter N fertilizer requirements and sequester SOC was investigated in this study. The APSIM model was calibrated with data from field and laboratory studies of trash decomposition in the wet tropics of northern Australia. APSIM was then validated against four independent data sets, before simulating location × soil × fertilizer × trash management scenarios. Soil carbon increased in trash blanketed soils relative to SOC in soils with burnt trash. However, further increases in SOC for the study region may be limited because the SOC in trash blanketed soils could be approaching equilibrium; future GHG mitigation efforts in this region should therefore focus on N fertilizer management. Simulated N fertilizer rates were able to be reduced from conventional rates regardless of trash management, because of low yield potential in the wet tropics. For crops subjected to continuous trash blanketing, there was substantial immobilization of N in decomposing trash so conventional N fertilizer rates were required for up to 24 years after trash blanketing commenced. After this period, there was potential to reduce N

  1. Long Term Sugarcane Crop Residue Retention Offers Limited Potential to Reduce Nitrogen Fertilizer Rates in Australian Wet Tropical Environments.

    PubMed

    Meier, Elizabeth A; Thorburn, Peter J

    2016-01-01

    The warming of world climate systems is driving interest in the mitigation of greenhouse gas (GHG) emissions. In the agricultural sector, practices that mitigate GHG emissions include those that (1) reduce emissions [e.g., those that reduce nitrous oxide (N2O) emissions by avoiding excess nitrogen (N) fertilizer application], and (2) increase soil organic carbon (SOC) stocks (e.g., by retaining instead of burning crop residues). Sugarcane is a globally important crop that can have substantial inputs of N fertilizer and which produces large amounts of crop residues ('trash'). Management of N fertilizer and trash affects soil carbon and nitrogen cycling, and hence GHG emissions. Trash has historically been burned at harvest, but increasingly is being retained on the soil surface as a 'trash blanket' in many countries. The potential for trash retention to alter N fertilizer requirements and sequester SOC was investigated in this study. The APSIM model was calibrated with data from field and laboratory studies of trash decomposition in the wet tropics of northern Australia. APSIM was then validated against four independent data sets, before simulating location × soil × fertilizer × trash management scenarios. Soil carbon increased in trash blanketed soils relative to SOC in soils with burnt trash. However, further increases in SOC for the study region may be limited because the SOC in trash blanketed soils could be approaching equilibrium; future GHG mitigation efforts in this region should therefore focus on N fertilizer management. Simulated N fertilizer rates were able to be reduced from conventional rates regardless of trash management, because of low yield potential in the wet tropics. For crops subjected to continuous trash blanketing, there was substantial immobilization of N in decomposing trash so conventional N fertilizer rates were required for up to 24 years after trash blanketing commenced. After this period, there was potential to reduce N fertilizer

  2. Using low-temperature thermochronometers to determine the long-term erosion rate pattern in the Olympic Mountains of Washington State

    NASA Astrophysics Data System (ADS)

    Stolar, D. B.; Brandon, M. T.; Willett, S. D.

    2006-12-01

    Models of convergent mountain building can be tested with low-temperature thermochronometers and similar data sets provided that mass and heat transport are reasonably well-understood in the setting of interest. Here, we consider the topographically-highest and most deeply-exhumed portion of the Cascadia accretionary wedge, the Olympic Mountains of Washington State, where previous work suggests the long-term steadiness of the pattern of surface erosion and, hence, the mean topography and the temperature and rock velocity fields since soon after the onset of exhumation around 15-18 Ma. We test the hypothesis of a steady erosion rate pattern in the Olympic Mountains by using a thermo- mechanical model of a steady-state accretionary wedge and multiple low-temperature thermochronometers to solve for the patterns of mass influx (accretion) and mass outflux (surface erosion) through the Cascadia margin. Inversions of synthetic data indicate that the methodology is capable of accurately resolving the pattern of surface erosion. Inversions of real data appear to constrain both the duration and pattern of steady surface erosion. Vitrinite reflectance (VR) data, which record maximum temperatures, suggest that exhumation began ~15 Ma, matching previous estimates. Estimates of the erosion rate pattern from inversions of reset apatite fission track (AFT) and apatite (U-Th)/He (AHe) ages are in rough agreement with each other and with fluvial incision rates near the western coast of the Olympic Peninsula, suggesting a steady erosion rate pattern over many millions of years. Inversions of reset zircon fission track (ZFT) ages suggest higher erosion rates in the core of the range than indicated by either the AFT or AHe data. Because the youngest reset ZFT age in the range is 9 Ma, we infer that the erosion rate pattern has remained relatively steady since 8 Ma. Finally, the erosion rate pattern determined from a simultaneous inversion of the AFT and AHe ages does not agree with

  3. Male and Female Subpopulations of Salix viminalis Present High Genetic Diversity and High Long-Term Migration Rates between Them.

    PubMed

    Zhai, Feifei; Mao, Jinmei; Liu, Junxiang; Peng, Xiangyong; Han, Lei; Sun, Zhenyuan

    2016-01-01

    Dioecy distributed in 157 flowering plant families and 959 flowering plant genera. Morphological and physiological differences between male and female plants have been studied extensively, but studies of sex-specific genetic diversity are relatively scarce in dioecious plants. In this study, 20 SSR loci were employed to examine the genetic variance of male subpopulations and female subpopulations in Salix viminalis. The results showed that all of the markers were polymorphic (Na = 14.15, He = 0.7566) and workable to reveal the genetic diversity of S. viminalis. No statistically significant difference was detected between male and female subpopulations, but the average genetic diversity of male subpopulations (Na = 7.12, He = 0.7071) and female subpopulations (Na = 7.31, He = 0.7226) were high. Under unfavorable environments (West Liao basin), the genetic diversity between male and female subpopulations was still not significantly different, but the genetic diversity of sexual subpopulations were lower. The differentiation of the ten subpopulations in S. viminalis was moderate (FST = 0.0858), which was conformed by AMOVA that most of genetic variance (94%) existed within subpopulations. Pairwise FST indicated no differentiation between sexual subpopulations, which was accompanied by high long-term migrate between them (M = 0.73~1.26). However, little recent migration was found between sexual subpopulations. Therefore, artificial crossing or/and transplantation by cutting propagation should be carried out so as to increase the migration during the process of ex situ conservation. PMID:27047511

  4. Male and Female Subpopulations of Salix viminalis Present High Genetic Diversity and High Long-Term Migration Rates between Them

    PubMed Central

    Zhai, Feifei; Mao, Jinmei; Liu, Junxiang; Peng, Xiangyong; Han, Lei; Sun, Zhenyuan

    2016-01-01

    Dioecy distributed in 157 flowering plant families and 959 flowering plant genera. Morphological and physiological differences between male and female plants have been studied extensively, but studies of sex-specific genetic diversity are relatively scarce in dioecious plants. In this study, 20 SSR loci were employed to examine the genetic variance of male subpopulations and female subpopulations in Salix viminalis. The results showed that all of the markers were polymorphic (Na = 14.15, He = 0.7566) and workable to reveal the genetic diversity of S. viminalis. No statistically significant difference was detected between male and female subpopulations, but the average genetic diversity of male subpopulations (Na = 7.12, He = 0.7071) and female subpopulations (Na = 7.31, He = 0.7226) were high. Under unfavorable environments (West Liao basin), the genetic diversity between male and female subpopulations was still not significantly different, but the genetic diversity of sexual subpopulations were lower. The differentiation of the ten subpopulations in S. viminalis was moderate (FST = 0.0858), which was conformed by AMOVA that most of genetic variance (94%) existed within subpopulations. Pairwise FST indicated no differentiation between sexual subpopulations, which was accompanied by high long-term migrate between them (M = 0.73~1.26). However, little recent migration was found between sexual subpopulations. Therefore, artificial crossing or/and transplantation by cutting propagation should be carried out so as to increase the migration during the process of ex situ conservation. PMID:27047511

  5. 5 CFR 1655.7 - Interest rate.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... interest rate established by the Department of the Treasury in effect on the date the TSP record keeper... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Interest rate. 1655.7 Section 1655.7 Administrative Personnel FEDERAL RETIREMENT THRIFT INVESTMENT BOARD LOAN PROGRAM § 1655.7 Interest rate....

  6. 7 CFR 3550.66 - Interest rate.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... DIRECT SINGLE FAMILY HOUSING LOANS AND GRANTS Section 502 Origination § 3550.66 Interest rate. Loans will be written using the applicable RHS interest rate in effect at loan approval or loan closing... 7 Agriculture 15 2011-01-01 2011-01-01 false Interest rate. 3550.66 Section 3550.66...

  7. 5 CFR 1655.7 - Interest rate.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... interest rate established by the Department of the Treasury in effect on the date the TSP record keeper... 5 Administrative Personnel 3 2011-01-01 2011-01-01 false Interest rate. 1655.7 Section 1655.7 Administrative Personnel FEDERAL RETIREMENT THRIFT INVESTMENT BOARD LOAN PROGRAM § 1655.7 Interest rate....

  8. 7 CFR 1980.423 - Interest rates.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Public Law 103-354 449-14. (4) It is permissible to have one interest rate on the guaranteed portion of... or its successor agency under Public Law 103-354 is a holder and must affirm or reject interest rate...) reflecting the interest rate change. The FmHA or its successor agency under Public Law 103-354 loan file,...

  9. Long-term observations of SO2 gas emission rates from Nyiragongo volcano (RD Congo) during 2004-2009

    NASA Astrophysics Data System (ADS)

    Yalire, Matthiew; Galle, Bo; Arellano, Santiago; Norman, Patrik; Johansson, Mattias

    2010-05-01

    volcanological observations is presented. This study emphasizes the importance of long-term and continuous gas monitoring to better understand the human and environmental effects of the persistent activity of this volcano.

  10. Long-term slip rate of the southern San Andreas Fault, from 10Be-26Al surface exposure dating of an offset alluvial fan

    SciTech Connect

    der Woerd, J v; Klinger, Y; Sieh, K; Tapponnier, P; Ryerson, F; M?riaux, A

    2006-01-13

    We determine the long-term slip rate of the southern San Andreas Fault in the southeastern Indio Hills using {sup 10}Be and {sup 26}Al isotopes to date an offset alluvial fan surface. Field mapping complemented with topographic data, air photos and satellite images allow to precisely determine piercing points across the fault zone that are used to measure an offset of 565 {+-} 80 m. A total of twenty-six quartz-rich cobbles from three different fan surfaces were collected and dated. The tight cluster of nuclide concentrations from 19 samples out of 20 from the offset fan surface implies a simple exposure history, negligible prior exposure and erosion, and yield an age of 35.5 {+-} 2.5 ka. The long-term slip rate of the San Andreas Fault south of Biskra Palms is thus 15.9 {+-} 3.4 mm/yr. This rate is about 10 mm/yr slower than geological (0-14 ka) and short-term geodetic estimates for this part of the San Andreas Fault implying changes in slip rate or in faulting behavior. This result puts new constraints on the slip rate of the San Jacinto and on the Eastern California Shear Zone for the last 35 ka. Our study shows that more sites along the major faults of southern California need to be targeted to better constrain the slip-rates over different time scales.

  11. Long-term cattle gain responses to stocking rate and grazing systems in northern mixed-grass prairie

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The effects of stocking rate and grazing system on gains of yearling beef cattle grazing rangelands have largely been addressed in short-term (<10 yr) studies, and often stocking rates are confounded within grazing systems with higher stocking rates for short-duration rotational grazing systems comp...

  12. 7 CFR 3575.33 - Interest rates.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... negotiated between the lender and the borrower. They may be either fixed or variable rates. Interest rates... business and are subject to Agency review and approval. (b) Variable rate publication. A variable interest... more often than quarterly). (2) The lender must incorporate within the variable rate note,...

  13. 7 CFR 3575.33 - Interest rates.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... negotiated between the lender and the borrower. They may be either fixed or variable rates. Interest rates... business and are subject to Agency review and approval. (b) Variable rate publication. A variable interest... more often than quarterly). (2) The lender must incorporate within the variable rate note,...

  14. 7 CFR 1980.320 - Interest rate.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... exceed the established applicable usury rate. Loans guaranteed under this subpart must bear a fixed interest rate over the life of the loan. The rate shall be agreed upon by the borrower and the Lender...

  15. 7 CFR 1980.320 - Interest rate.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... exceed the established, applicable usury rate. Loans guaranteed under this subpart must bear a fixed interest rate over the life of the loan. The rate shall be agreed upon by the borrower and the Lender...

  16. 5 CFR 1655.7 - Interest rate.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... processes the paper application or on the date the request is entered on the TSP Web site. (b) The interest... 5 Administrative Personnel 3 2012-01-01 2012-01-01 false Interest rate. 1655.7 Section 1655.7 Administrative Personnel FEDERAL RETIREMENT THRIFT INVESTMENT BOARD LOAN PROGRAM § 1655.7 Interest rate....

  17. 5 CFR 1655.7 - Interest rate.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... processes the paper application or on the date the request is entered on the TSP Web site. (b) The interest... 5 Administrative Personnel 3 2013-01-01 2013-01-01 false Interest rate. 1655.7 Section 1655.7 Administrative Personnel FEDERAL RETIREMENT THRIFT INVESTMENT BOARD LOAN PROGRAM § 1655.7 Interest rate....

  18. 5 CFR 1655.7 - Interest rate.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... processes the paper application or on the date the request is entered on the TSP Web site. (b) The interest... 5 Administrative Personnel 3 2014-01-01 2014-01-01 false Interest rate. 1655.7 Section 1655.7 Administrative Personnel FEDERAL RETIREMENT THRIFT INVESTMENT BOARD LOAN PROGRAM § 1655.7 Interest rate....

  19. 8 CFR 293.2 - Interest rate.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Interest rate. 293.2 Section 293.2 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS DEPOSIT OF AND INTEREST ON CASH RECEIVED TO SECURE IMMIGRATION BONDS § 293.2 Interest rate. The Secretary of the Treasury...

  20. 8 CFR 293.2 - Interest rate.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Interest rate. 293.2 Section 293.2 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS DEPOSIT OF AND INTEREST ON CASH RECEIVED TO SECURE IMMIGRATION BONDS § 293.2 Interest rate. The Secretary of the Treasury...

  1. Effects of Climate on Long-term Rates of Physical Erosion and Chemical Weathering: Evidence from Cosmogenic Nuclides and Geochemical Mass Balance

    NASA Astrophysics Data System (ADS)

    Kirchner, J. W.; Riebe, C. S.; Ferrier, K. L.; Finkel, R. C.

    2004-12-01

    Cosmogenic nuclides such as 10Be and 26Al have recently become important tools for measuring long-term denudation rates. We have recently shown how cosmogenic nuclide measurements of denudation fluxes can be partitioned into their physical and chemical components, using the enrichment of insoluble tracers in regolith relative to its parent rock. We used these methods to measure long-term rates of physical erosion and chemical weathering for 42 sites, encompassing widely varying climates and denudation rates. Across these sites, mean annual temperatures vary from 2 to 25 ° C, average annual precipitation spans a 20-fold range (from 22 to 420 cm/yr), and denudation rates vary by 32-fold (from 23 to 755 t km-2 yr-2). Our measurements show that chemical weathering rates are tightly coupled with physical erosion rates, such that the relationship between climate and chemical weathering rates may be obscured by site-to-site differences in the rate that minerals are supplied to soil by physical erosion of rock. The relative importance of chemical weathering can be quantified using the "Weathering Intensity Factor" (WIF), the ratio of the chemical weathering rate to the physical erosion rate. Over 60 percent of the variance in WIF's can be explained by a simple Arrhenius-like relationship based on mean annual temperature and average annual precipitation. The temperature-dependence of WIF is roughly half of what one would expect from laboratory measurements of activation energies for feldspar weathering and previous inter-comparisons of short-term average weathering rates from the field. Our results imply that the strength of climate change feedbacks between temperature and silicate weathering rates may be weaker than previously thought, at least in actively eroding, unglaciated granitic terrain similar to our study sites.

  2. Long-term and short-term erosion rates in river catchments of the Rhenish Massif and the Black Forest, Germany

    NASA Astrophysics Data System (ADS)

    Meyer, H.; Hetzel, R.; Strauss, H.

    2007-12-01

    We constrained long-term erosion rates from the concentration of cosmogenic 10Be in stream sediments in order to quantify the Late Quaternary denudation history of mountain ranges in central Europe. Four different catchments in Germany, ranging in size from 8 to 379 km2 were investigated. Two of them, the Aabach and Möhne catchments drain predominantly low-grade Paleozoic metasediments. The other two, the Gutach and Acher catchments in the Black Forest are situated in Late Paleozoic granites. Erosion rates derived from the 10Be concentrations range from 29 to 86 mm/ka in the Rhenish Massif and from 26 to 91 mm/ka in the Black Forest. These spatially-averaged erosion rates integrate over the past 7 to 23 ka. Central to our investigation are questions concerning the relative importance of lithology and catchment relief on long-term erosion rates. Short-term erosion rates for all catchments were quantified by combining the amounts of suspended and dissolved loads in water samples with water discharge data and basin area. By analyzing the stable isotope signatures δ18O of river water and δ13C of dissolved anorganic carbon and by taking into account the precipitation and evaporation we corrected the dissolved load for organic, atmospheric and anthropogenic inputs. The preliminary short-term erosion rates vary between 9 and 33 mm/ka and are only about one third of the erosion rates derived from 10Be. The short-term erosion rates are complemented by erosion rates derived from the volume of sediment stored behind reservoirs of known age. These erosion rates range from 2 to 13 mm/ka and are lower than the erosion rates derived from river loads, as they do not take into account the dissolved load. Furthermore, we focused on dependence of lithology and land use on short-term erosion rates.

  3. Short-term and long-term effects of low total pressure on gas exchange rates of spinach.

    PubMed

    Iwabuchi, K; Kurata, K

    2003-01-01

    In this study, spinach plants were grown under atmospheric and low pressure conditions with constant O2 and CO2 partial pressures, and the effects of low total pressure on gas exchange rates were investigated. CO2 assimilation and transpiration rates of spinach grown under atmospheric pressure increased after short-term exposure to low total pressure due to the enhancement of leaf conductance. However, gas exchange rates of plants grown at 25 kPa total pressure were not greater than those grown at atmospheric pressure. Stomatal pore length and width were significantly smaller in leaves grown at low total pressure. This result suggested that gas exchange rates of plants grown under low total pressure were not stimulated even with the enhancement of gas diffusion because the stomatal size and stomatal aperture decreased. PMID:12580188

  4. Short-term and long-term effects of low total pressure on gas exchange rates of spinach

    NASA Astrophysics Data System (ADS)

    Iwabuchi, K.; Kurata, K.

    In this study, spinach plants were grown under atmospheric and low pressure conditions with constant O2 and CO2 partial pressures, and the effects of low total pressure on gas exchange rates were investigated. CO2 assimilation and transpiration rates of spinach grown under atmospheric pressure increased after short-term exposure to low total pressure due to the enhancement of leaf conductance. However, gas exchange rates of plants grown at 25 kPa total pressure were not greater than those grown at atmospheric pressure. Stomatal pore length and width were significantly smaller in leaves grown at low total pressure. This result suggested that gas exchange rates of plants grown under low total pressure were not stimulated even with the enhancement of gas diffusion because the stomatal size and stomatal aperture decreased.

  5. The use of a passive sampler for the simultaneous determination of long-term ventilation rates and VOC concentrations

    SciTech Connect

    Mailahn, W.; Seifert, B.; Ullrich, D. ); Moriske, H. )

    1989-01-01

    When interpreting seasonal variations of indoor concentrations of volatile organic compounds (VOC), the ventilation rate must be known. Therefore, a method has been developed which permits the simultaneous determination of the average ventilation rate and the concentration of VOC in a room over an integration period of two week with the same passive sampler. Hexafluorobenzene (HFB), a non-toxic substance, was chosen as the tracer so as not to interfere in the gas chromatographic analysis of VOC in indoor air. Emission rates of HFB sources were determined at various temperatures from 15 to 30{degree}C. After a test of the procedure for sampling periods of one and two weeks in an experimental chamber at ventilation rates between 0.5 and 2 h{sup {minus}1}, the procedure was successfully applied under field conditions. Good agreement was obtained when comparing the HFB method with a perfluorocarbon technique.

  6. Long-term monitoring of creep rate along the Hayward fault and evidence for a lasting creep response to 1989 Loma Prieta earthquake

    USGS Publications Warehouse

    Lienkaemper, J.J.; Galehouse, J.S.; Simpson, R.W.

    2001-01-01

    We present results from over 30 yr of precise surveys of creep along the Hayward fault. Along most of the fault, spatial variability in long-term creep rates is well determined by these data and can help constrain 3D-models of the depth of the creeping zone. However, creep at the south end of the fault stopped completely for more than 6 years after the M7 1989 Loma Prieta Earthquake (LPEQ), perhaps delayed by stress drop imposed by this event. With a decade of detailed data before LPEQ and a decade after it, we report that creep response to that event does indeed indicate the expected deficit in creep.

  7. Long-term testing

    NASA Astrophysics Data System (ADS)

    Ferber, M.; Graves, G. A., Jr.

    Land-based gas turbines are significantly different from automotive gas turbines in that they are designed to operate for 50,000 h or greater (compared to 5,000-10,000 h). The primary goal of this research is to determine the long-term survivability of ceramic materials for industrial gas turbine applications. Research activities in this program focus on the evaluation of the static tensile creep and stress rupture (SR) behavior of three commercially available structural ceramics which have been identified by the gas turbine manufacturers as leading candidates for use in industrial gas turbines. For each material investigated, a minimum of three temperatures and four stresses will be used to establish the stress and temperature sensitivities of the creep and SR behavior. Because existing data for many candidate structural ceramics are limited to testing times less than 2,000 h, this program will focus on extending these data to times on the order of 10,000 h, which represents the lower limit of operating time anticipated for ceramic blades and vanes in gas turbine engines. A secondary goal of the program will be to investigate the possibility of enhancing life prediction estimates by combining interrupted tensile SR tests and tensile dynamic fatigue tests in which tensile strength is measured as a function of stressing rate. The third goal of this program will be to investigate the effects of water vapor upon the SR behavior of the three structural ceramics chosen for the static tensile studies by measuring the flexural strength as a function of stressing rate at three temperatures.

  8. Long-term testing

    SciTech Connect

    Ferber, M.; Graves, G.A. Jr.

    1994-12-31

    Land-based gas turbines are significantly different from automotive gas turbines in that they are designed to operate for 50,000 h or greater (compared to 5,000--10,000 h). The primary goal of this research is to determine the long-term survivability of ceramic materials for industrial gas turbine applications. Research activities in this program focus on the evaluation of the static tensile creep and stress rupture (SR) behavior of three commercially available structural ceramics which have been identified by the gas turbine manufacturers as leading candidates for use in industrial gas turbines. For each material investigated, a minimum of three temperatures and four stresses will be used to establish the stress and temperature sensitivities of the creep and SR behavior. Because existing data for many candidate structural ceramics are limited to testing times less than 2,000 h, this program will focus on extending these data to times on the order of 10,000 h, which represents the lower limit of operating time anticipated for ceramic blades and vanes in gas turbine engines. A secondary goal of the program will be to investigate the possibility of enhancing life prediction estimates by combining interrupted tensile SR tests and tensile dynamic fatigue tests in which tensile strength is measured as a function of stressing rate. The third goal of this program will be to investigate the effects of water vapor upon the SR behavior of the three structural ceramics chosen for the static tensile studies by measuring the flexural strength as a function of stressing rate at three temperatures.

  9. Erosion rates at the Mars Exploration Rover landing sites and long-term climate change on Mars

    USGS Publications Warehouse

    Golombek, M.P.; Grant, J. A.; Crumpler, L.S.; Greeley, R.; Arvidson, R. E.; Bell, J.F., III; Weitz, C.M.; Sullivan, R.J.; Christensen, P.R.; Soderblom, L.A.; Squyres, S. W.

    2006-01-01

    Erosion rates derived from the Gusev cratered plains and the erosion of weak sulfates by saltating sand at Meridiani Planum are so slow that they argue that the present dry and desiccating environment has persisted since the Early Hesperian. In contrast, sedimentary rocks at Meridiani formed in the presence of groundwater and occasional surface water, and many Columbia Hills rocks at Gusev underwent aqueous alteration during the Late Noachian, approximately coeval with a wide variety of geomorphic indicators that indicate a wetter and likely warmer environment. Two-toned rocks, elevated ventifacts, and perched and undercut rocks indicate localized deflation of the Gusev plains and deposition of an equivalent amount of sediment into craters to form hollows, suggesting average erosion rates of ???0.03 nm/yr. Erosion of Hesperian craters, modification of Late Amazonian craters, and the concentration of hematite concretions in the soils of Meridiani yield slightly higher average erosion rates of 1-10 nm/yr in the Amazonian. These erosion rates are 2-5 orders of magnitude lower than the slowest continental denudation rates on Earth, indicating that liquid water was not an active erosional agent. Erosion rates for Meridiani just before deposition of the sulfate-rich sediments and other eroded Noachian areas are comparable with slow denudation rates on Earth that are dominated by liquid water. Available data suggest the climate change at the landing sites from wet and likely warm to dry and desiccating occurred sometime between the Late Noachian and the beginning of the Late Hesperian (3.7-3.5 Ga). Copyright 2006 by the American Geophysical Union.

  10. Erosion Rates at the Mars Exploration Rover Landing Sites and Long-Term Climate Change on Mars

    NASA Technical Reports Server (NTRS)

    Golombek, M. P.; Grant, J. A.; Crumpler, L. S.; Greeley, R.; Arvidson, R. E.; Bell, J. F., III; Weitz, C. M.; Sullivan, R.; Christensen, P. R.; Soderblom, L. A.; Squyres, S. W.

    2006-01-01

    Erosion rates derived from the Gusev cratered plains and the erosion of weak sulfates by saltating sand at Meridiani Planum are so slow that they argue that the present dry and desiccating environment has persisted since the Early Hesperian. In contrast, sedimentary rocks at Meridiani formed in the presence of groundwater and occasional surface water, and many Columbia Hills rocks at Gusev underwent aqueous alteration during the Late Noachian, approximately coeval with a wide variety of geomorphic indicators that indicate a wetter and likely warmer environment. Two-toned rocks, elevated ventifacts, and perched and undercut rocks indicate localized deflation of the Gusev plains and deposition of an equivalent amount of sediment into craters to form hollows, suggesting average erosion rates of approx.0.03 nm/yr. Erosion of Hesperian craters, modification of Late Amazonian craters, and the concentration of hematite concretions in the soils of Meridiani yield slightly higher average erosion rates of 1-10 nm/yr in the Amazonian. These erosion rates are 2-5 orders of magnitude lower than the slowest continental denudation rates on Earth, indicating that liquid water was not an active erosional agent. Erosion rates for Meridiani just before deposition of the sulfate-rich sediments and other eroded Noachian areas are comparable with slow denudation rates on Earth that are dominated by liquid water. Available data suggest the climate change at the landing sites from wet and likely warm to dry and desiccating occurred sometime between the Late Noachian and the beginning of the Late Hesperian (3.7-3.5 Ga).

  11. 7 CFR 1950.105 - Interest rate.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... handling Single Family Housing Loans are contained in 7 CFR part 3550. ... 7 Agriculture 14 2010-01-01 2009-01-01 true Interest rate. 1950.105 Section 1950.105 Agriculture... rate. (a) The Soldiers and Sailors Relief Act requires that the effective interest rate charged...

  12. A new animal model for evaluation of long-term growth rate over one month by rhGH/PLGA microcapsule formulations.

    PubMed

    Takada, Shigeyuki; Kurokawa, Tomofumi; Misaki, Masafumi; Taira, Keiko; Yamagata, Yutaka

    2003-07-01

    A new animal model to evaluate the long-term growth rate produced by a sustained-release formulation of recombinant human growth hormone (rhGH) over one month was developed and the usefulness of our microcapsule formulations was demonstrated in this model. Long-term pharmacological effects by subcutaneous injection of microcapsules for sustained release of rhGH were evaluated in hypophysectomized (Hpx) rats treated with immunosuppressive agent along with hormone supplement. Copoly(DL-lactic/glycolic)acid (PLGA) microcapsules for sustained release of rhGH, a two-week sustained-release formulation (rhGH-SR-2W) and a one-month sustained-release formulation (rhGH-SR-1M), were prepared by a solid-in-oil-in-water emulsion solvent evaporation technique. Body-weight gain, body-length gain and serum levels of rat insulin-like growth factor-I (rIGF-I) induced by subcutaneous injection of rhGH-SR were compared with those by daily injections of rhGH solution in Hpx rats for 35 days. Serum IGF-I levels in Hpx rats after the injection of rhGH-SR2W microcapsules were higher than those after daily injections of rhGH solution. Body-length gain, a new parameter, after single injection of rhGH-SR-1M microcapsules demonstrated the higher growth rate than that after daily injections of rhGH solution for 35 days. Thus, single injection of rhGH-SR microcapsules demonstrated long-term pharmacological effects greater than those by daily injections of rhGH solution in a newly developed model, immunosuppressed Hpx rats. PMID:12906752

  13. THE LONG-TERM DECAY IN PRODUCTION RATES FOLLOWING THE EXTREME OUTBURST OF COMET 17P/HOLMES

    SciTech Connect

    Schleicher, David G.

    2009-10-15

    Numerous sets of narrowband filter photometry were obtained of Comet 17P/Holmes from Lowell Observatory during the interval of 2007 November 1 to 2008 March 5. Observations began 8 days following its extreme outburst, at which time the derived water production rate, based on OH measurements, was 5 x 10{sup 29} molecule s{sup -1} and the derived proxy of dust production, A({theta})f{rho}, was about 5 x 10{sup 5} cm. Relative production rates for the other gas species, CN, C{sub 2}, C{sub 3}, and NH, are consistent with 'typical' composition (based on our update to the classifications by A'Hearn et al.). An exponential decay in the logarithm of measured production rates as a function of time was observed for all species, with each species dropping by factors of about 200-500 after 125 days. All gas species exhibited clear trends with aperture size, and these trends are consistent with larger apertures having a greater proportion of older material that was released when production rates were higher. Much larger aperture trends were measured for the dust, most likely because the dust grains have smaller outflow velocities and longer lifetimes than the gas species; therefore, a greater proportion of older, i.e., higher production dust is contained within a given aperture. By extrapolating to a sufficiently small aperture size, we derive near-instantaneous water and dust production rates throughout the interval of observation, and also estimate values immediately following the outburst. The finite lifetime of the gas species requires that much higher ice vaporization rates were taking place throughout the observation interval than occurred prior to the outburst, likely due to the continued release of icy grains from the nucleus. The relatively small aperture trends for the gas species also imply that the bulk of fresh, excess volatiles are confined to the nucleus and near-nucleus regime, rather than being associated with the outburst ejecta cloud. A minimum of about 0

  14. Visualization of Heart Rate Variability of Long-Term Heart Transplant Patient by Transition Networks: A Case Report

    PubMed Central

    Wdowczyk, Joanna; Makowiec, Danuta; Dorniak, Karolina; Gruchała, Marcin

    2016-01-01

    We present a heart transplant patient at his 17th year of uncomplicated follow-up. Within a frame of routine check out several tests were performed. With such a long and uneventful follow-up some degree of graft reinnervation could be anticipated. However, the patient's electrocardiogram and exercise parameters seemed largely inconclusive in this regard. The exercise heart rate dynamics were suggestive of only mild, if any parasympathetic reinnervation of the graft with persisting sympathetic activation. On the other hand, traditional heart rate variability (HRV) indices were inadequately high, due to erratic rhythm resulting from interference of the persisting recipient sinus node or non-conducted atrial parasystole. New tools, originated from network representation of time series, by visualization short-term dynamical patterns, provided a method to discern HRV increase due to reinnervation from other reasons. PMID:27014081

  15. Visualization of Heart Rate Variability of Long-Term Heart Transplant Patient by Transition Networks: A Case Report.

    PubMed

    Wdowczyk, Joanna; Makowiec, Danuta; Dorniak, Karolina; Gruchała, Marcin

    2016-01-01

    We present a heart transplant patient at his 17th year of uncomplicated follow-up. Within a frame of routine check out several tests were performed. With such a long and uneventful follow-up some degree of graft reinnervation could be anticipated. However, the patient's electrocardiogram and exercise parameters seemed largely inconclusive in this regard. The exercise heart rate dynamics were suggestive of only mild, if any parasympathetic reinnervation of the graft with persisting sympathetic activation. On the other hand, traditional heart rate variability (HRV) indices were inadequately high, due to erratic rhythm resulting from interference of the persisting recipient sinus node or non-conducted atrial parasystole. New tools, originated from network representation of time series, by visualization short-term dynamical patterns, provided a method to discern HRV increase due to reinnervation from other reasons. PMID:27014081

  16. Outcomes of High-Dose-Rate Interstitial Brachytherapy in the Treatment of Locally Advanced Cervical Cancer: Long-term Results

    SciTech Connect

    Pinn-Bingham, Melva; Puthawala, Ajmel A.; Syed, A.M. Nisar; Sharma, Anil; DiSaia, Philip; Berman, Michael; Tewari, Krishnansu S.; Randall-Whitis, Leslie; Mahmood, Usama; Ramsinghani, Nilam; Kuo, Jeffrey; Chen, Wen-Pin; McLaren, Christine E.

    2013-03-01

    Purpose: The purpose of this study was to determine locoregional control (LRC), disease-free survival (DFS), and toxicity of high-dose-rate interstitial brachytherapy (HDR-ISBT) in the treatment of locally advanced cervical cancer. Methods and Materials: Between March 1996 and May 2009, 116 patients with cervical cancer were treated. Of these, 106 (91%) patients had advanced disease (International Federation of Gynecology and Obstetrics stage IIB-IVA). Ten patients had stage IB, 48 had stage II, 51 had stage III, and 7 had stage IVA disease. All patients were treated with a combination of external beam radiation therapy (EBRT) to the pelvis (5040 cGy) and 2 applications of HDR-ISBT to a dose of 3600 cGy to the implanted volume. Sixty-one percent of patients also received interstitial hyperthermia, and 94 (81%) patients received chemotherapy. Results: Clinical LRC was achieved in 99 (85.3%) patients. Three-year DFS rates were 59%, 67%, 71%, and 57% for patients with stage IB, II, III, and IVA disease, respectively. The 5-year DFS and overall survival rates for the entire group were 60% and 44%, respectively. Acute and late toxicities were within acceptable limits. Conclusions: Locally advanced cervical cancer patients for whom intracavitary BT is unsuitable can achieve excellent LRC and OS with a combination of EBRT and HDR-ISBT.

  17. Outcomes of High-Dose-Rate Interstitial Brachytherapy in the Treatment of Locally Advanced Cervical Cancer: Long-term Results

    PubMed Central

    Pinn-Bingham, Melva; Puthawala, Ajmel A.; Syed, A.M. Nisar; Sharma, Anil; DiSaia, Philip; Berman, Michael; Tewari, Krishnansu S.; Randall-Whitis, Leslie; Mahmood, Usama; Ramsinghani, Nilam; Kuo, Jeffrey; Chen, Wen-Pin; McLaren, Christine E.

    2013-01-01

    Purpose The purpose of this study was to determine locoregional control (LRC), disease-free survival (DFS), and toxicity of high-dose-rate interstitial brachytherapy (HDR-ISBT) in the treatment of locally advanced cervical cancer. Methods and Materials Between March 1996 and May 2009, 116 patients with cervical cancer were treated. Of these, 106 (91%) patients had advanced disease (International Federation of Gynecology and Obstetrics stage IIB-IVA). Ten patients had stage IB, 48 had stage II, 51 had stage III, and 7 had stage IVA disease. All patients were treated with a combination of external beam radiation therapy (EBRT) to the pelvis (5040 cGy) and 2 applications of HDR-ISBT to a dose of 3600 cGy to the implanted volume. Sixty-one percent of patients also received interstitial hyperthermia, and 94 (81%) patients received chemotherapy. Results Clinical LRC was achieved in 99 (85.3%) patients. Three-year DFS rates were 59%, 67%, 71%, and 57% for patients with stage IB, II, III, and IVA disease, respectively. The 5-year DFS and overall survival rates for the entire group were 60% and 44%, respectively. Acute and late toxicities were within acceptable limits. Conclusions Locally advanced cervical cancer patients for whom intracavitary BT is unsuitable can achieve excellent LRC and OS with a combination of EBRT and HDR-ISBT. PMID:22763030

  18. Effect of age-at-release on long term sexual re-offense rates in civilly committed sexual offenders.

    PubMed

    Prentky, Robert Alan; Lee, Austin F S

    2007-03-01

    A cohort of 136 rapists and 115 child molesters civilly committed to a prison in Massachusetts and followed for 25 years (see Prentky, Lee, Knight, & Cerce, 1997) was examined for the effect of age at time of release on sexual recidivism. The present study (1) examined the recidivism rates for each of five age-at-release groups, separately for rapists and child molesters, (2) tested the fit of linear and quadratic models for 5, 10, 15, 20, and 25-year windows using Cox regression analysis, (3) presented the predicted failure rates for rapists (up to five years post-release) and child molesters (out 21 years post-release), and (4) provided a computational formula for estimating the sexual recidivism rate given an individual's age and number of years post-release. For rapists, a linear model extending 5 years best captured our data (LR=5.62, p<.02). Going out any further than 5 years did not enhance the predictive efficacy of the model. By contrast, a quadratic model extending the full duration of the study (25 years) provided the best fit (LR=6.30, p<.04) for child molesters. Our data supported the general conclusion that risk of sexual recidivism diminishes as a function of increasing age at time of release for rapists. We found marked differences, however, in the re-offense patterns of rapists and child molesters, with the latter group evidencing a distinct quadratic, rather than linear, pattern. Since these findings derive from a population screened for civil commitment by virtue of their presumptive dangerousness, they may not be generalizable to samples of sex offenders drawn from the general prison population. PMID:17334931

  19. A long-term rock uplift rate for eastern Crete and geodynamic implications for the Hellenic subduction zone

    NASA Astrophysics Data System (ADS)

    Strobl, M.; Hetzel, R.; Fassoulas, C.; Kubik, P.

    2014-12-01

    The island of Crete in the forearc of the Hellenic subduction zone has a rugged topography with a local relief exceeding 2 km. Based on the elevation of marine shorelines, rates of rock uplift during the Late Holocene were previously estimated to range between 1 and 4 mm/a in different parts of the island (e.g. Lambeck, 1995). These rates may, however, not be representative for longer timescales, because subduction earthquakes with up to 9 m of vertical coseismic displacement have recently affected Crete (Stiros, 2001). Here we use a well preserved sequence of marine terraces near Kato Zakros in eastern Crete to determine the rate of rock uplift over the last ˜600 ka. Field investigations and topographic profiles document a flight of more than 13 marine bedrock terraces that were carved into limestones of the Tripolitza unit. Preliminary age constraints for the terraces were obtained by 10Be exposure dating of rare quartz-bearing sandstone clasts, which are present on some terraces. The 10Be ages of these samples, which have been corrected for an inherited nuclide component, yielded exposure ages between ˜100 ka and zero. Combined with geomorphologic evidence the two oldest 10Be ages suggest that the terraces T4 and T5, with shoreline angles at an elevation of ca. 68 and ca. 76 m above sea level, respectively, formed during the marine isotope stage 5e about 120 ka ago. The correlation of the higher terraces (T6 to T13) with regional sea-level high-stands (Siddall et al., 2003) indicates sustained rock uplift at a rate of ˜0.5 m/ka since at least ˜600 ka. As normal faulting has dominated the tectonics of Crete during the last several million years, upper crustal shortening can be ruled out as a cause for rock uplift. We argue that the sustained uplift of the island results from the continuous underplating of sediments, which are transferred from the subducting African plate to the base of the crust beneath Crete. Lambeck, 1995, Geophys. J. Int. 122, 1022

  20. Using the Autism Detection in Early Childhood (ADEC) and Childhood Autism Rating Scales (CARS) to predict long term outcomes in children with autism spectrum disorders.

    PubMed

    Nah, Yong-Hwee; Young, Robyn L; Brewer, Neil

    2014-09-01

    This study evaluated the predictive validity of the Autism Detection in Early Childhood (ADEC; Young, Autism detection in early childhood: ADEC. Australian Council of Educational Research, Camberwell, VIC 2007) and a well-established screening tool, the Childhood Autism Rating Scale (CARS; Schopler et al. The childhood autism rating scale (CARS). Western Psychological Services, Los Angeles 1988), for long term outcomes of children with ASD engaged in an early intervention program. Participants were 55 children (44 male, 11 female) aged 19–42 months (M = 33.5, SD = 5.6) at initial assessment who were followed up 2 and 6 years after their initial assessment. The ADEC and the CARS performed similarly when predicting long term outcomes such as clinical diagnostic outcome and overall adaptive functioning level. However, only the ADEC score was significantly correlated with ASD symptom severity at the 6-year follow up. Although these findings need to be replicated with additional and larger samples, this study extends our understanding of the psychometric properties of both the ADEC and the CARS. PMID:24658894

  1. The impact of long-term water stress on relative growth rate and morphology of needles and shoots of Metasequoia glyptostroboides seedlings: research toward identifying mechanistic models.

    PubMed

    Zhang, Yanxiang; Equiza, Maria Alejandra; Zheng, Quanshui; Tyree, Melvin T

    2011-09-01

    Leaf morphology in the upper canopy of trees tends to be different from that lower down. The effect of long-term water stress on leaf growth and morphology was studied in seedlings of Metasequoia glyptostroboides to understand how tree height might affect leaf morphology in larger trees. Tree height increases water stress on growing leaves through increased hydraulic resistance to water flow and increased gravitational potential, hence we assume that water stress imposed by soil dehydration will have an effect equivalent to stress induced by height. Seedlings were subjected to well-watered and two constant levels of long-term water stress treatments. Drought treatment significantly reduced final needle count, area and mass per area (leaf mass area, LMA) and increased needle density. Needles from water-stressed plants had lower maximum volumetric elastic modulus (ε(max)), osmotic potential at full turgor (Ψ¹⁰⁰(π)) (and at zero turgor (Ψ⁰(π)) (than those from well-watered plants. Palisade and spongy mesophyll cell size and upper epidermal cell size decreased significantly in drought treatments. Needle relative growth rate, needle length and cell sizes were linear functions of the daily average water potential at the time of leaf growth (r² 0.88-0.999). We conclude that water stress alone does mimic the direction and magnitude of changes in leaf morphology observed in tall trees. The results are discussed in terms of various models for leaf growth rate. PMID:21534977

  2. Design of governmental policies for oil production rates and oil income spending; a long-term perspective

    SciTech Connect

    Moxnes, E.

    1983-01-01

    Norway is a small country with large oil reserves. In 1980, oil production amounted to 1 million barrels per day. Taxes and royalties to the government from this production provided 9% of the GNP. With current estimates of recoverable reserves, the 1980 production rate would last for 100 years. Because potential income is so large, decisions about oil production rates and oil income spending have tremendous impacts on society. The current debate provides a wide variety of policy suggestions. Attempts to design an appropriate oil policy are complicated by much uncertainty about total reserves, future oil prices, and complex economic responses to production and income. This report provides an integrating framework to aid government officials in their evaluation of policy options. A system dynamics model of the Norwegian national economy is developed for the analysis. The model determines endogenously the spending of oil income, GNP, consumption and investments, imports and exports, unemployment, and labor migration from exporting industries to service industries; all variables result from exogenous decisions about oil production.

  3. In a long-term experimental demography study, excluding ungulates reversed invader's explosive population growth rate and restored natives.

    PubMed

    Kalisz, Susan; Spigler, Rachel B; Horvitz, Carol C

    2014-03-25

    A major goal in ecology is to understand mechanisms that increase invasion success of exotic species. A recent hypothesis implicates altered species interactions resulting from ungulate herbivore overabundance as a key cause of exotic plant domination. To test this hypothesis, we maintained an experimental demography deer exclusion study for 6 y in a forest where the native ungulate Odocoileus virginianus (white-tailed deer) is overabundant and Alliaria petiolata (garlic mustard) is aggressively invading. Because population growth is multiplicative across time, we introduce metrics that correctly integrate experimental effects across treatment years, the cumulative population growth rate, λc, and its geometric mean, λper-year, the time-averaged annual population growth rate. We determined λc and λper-year of the invader and of a common native, Trillium erectum. Our results conclusively demonstrate that deer are required for the success of Alliaria; its projected population trajectory shifted from explosive growth in the presence of deer (λper-year = 1.33) to decline toward extinction where deer are excluded (λper-year = 0.88). In contrast, Trillium's λper-year was suppressed in the presence of deer relative to deer exclusion (λper-year = 1.04 vs. 1.20, respectively). Retrospective sensitivity analyses revealed that the largest negative effect of deer exclusion on Alliaria came from rosette transitions, whereas the largest positive effect on Trillium came from reproductive transitions. Deer exclusion lowered Alliaria density while increasing Trillium density. Our results provide definitive experimental support that interactions with overabundant ungulates enhance demographic success of invaders and depress natives' success, with broad implications for biodiversity and ecosystem function worldwide. PMID:24616522

  4. Coupling of Realistic Rate Estimates with Genomics for Assessing Contaminant Attenuation and Long-Term Plume Containment

    SciTech Connect

    Sorenson, Kent S. Jr.

    2003-06-01

    Natural attenuation of TCE under aerobic conditions at the INEEL Test Area North site was demonstrated largely on the basis of preferential loss of TCE relative to conservative solutes (PCE and H-3) along groundwater flow paths. First order degradation half-lives were calculated from the rate of preferential TCE loss. We are utilizing the same approach at other DOE sites that have aerobic TCE plumes to determine if aerobic natural attenuation of TCE is rapid enough at these sites to be environmentally significant, i.e. if natural attenuation can reduce concentrations to acceptable levels before groundwater reaches potential receptors. The first step in this process was to identify TCE plumes at DOE sites that have the appropriate site conditions and data needed to perform this analysis. The site conditions include the presence of TCE in groundwater at appreciable concentrations in an aerobic aquifer, a co-mingled contaminant that can be used as a conservative tracer (e.g. PCE, H-3, Tc-99), a flow path that represents at least a decade of travel time, and several monitoring wells located along this flow path. Candidate sites were identified through interviews with knowledgeable individuals in the DOE system and by screening the U.S. Dept. of Energy Groundwater Database using the keywords ''TCE'' and ''groundwater''. The initial screening yielded 25 plumes for consideration. These sites had anywhere from one to 37 individual plumes containing TCE. Of the 25 sites, 13 sites were further evaluated because they met the screening criteria or were promising. After contacting DOE personnel from the respective sites, they were divided into three groups: (1) sites that meet all the project criteria, (2) sites that could potentially be used for the project, and (3) DOE sites that did not meet the criteria. The five sites with plumes that met the criteria were: Brookhaven National Laboratory, Lawrence Livermore National Laboratory, Paducah Gaseous Diffusion Plant, Rocky Flats

  5. Long-term phenological trends, species accumulation rates, aphid traits and climate: five decades of change in migrating aphids

    PubMed Central

    Bell, James R; Alderson, Lynda; Izera, Daniela; Kruger, Tracey; Parker, Sue; Pickup, Jon; Shortall, Chris R; Taylor, Mark S; Verrier, Paul; Harrington, Richard

    2015-01-01

    1. Aphids represent a significant challenge to food production. The Rothamsted Insect Survey (RIS) runs a network of 12·2-m suction-traps throughout the year to collect migrating aphids. In 2014, the RIS celebrated its 50th anniversary. This paper marks that achievement with an extensive spatiotemporal analysis and the provision of the first British annotated checklist of aphids since 1964. 2. Our main aim was to elucidate mechanisms that advance aphid phenology under climate change and explain these using life-history traits. We then highlight emerging pests using accumulation patterns. 3. Linear and nonlinear mixed-effect models estimated the average rate of change per annum and effects of climate on annual counts, first and last flights and length of flight season since 1965. Two climate drivers were used: the accumulated day degrees above 16 °C (ADD16) indicated the potential for migration during the aphid season; the North Atlantic Oscillation (NAO) signalled the severity of the winter before migration took place. 4. All 55 species studied had earlier first flight trends at rate of β = −0·611 ± SE 0·015 days year−1. Of these species, 49% had earlier last flights, but the average species effect appeared relatively stationary (β = −0·010 ± SE 0·022 days year−1). Most species (85%) showed increasing duration of their flight season (β = 0·336 ± SE 0·026 days year−1), even though only 54% increased their log annual count (β = 0·002 ± SE <0·001 year−1). 5. The ADD16 and NAO were shown to drive patterns in aphid phenology in a spatiotemporal context. Early in the year when the first aphids were migrating, the effect of the winter NAO was highly significant. Further into the year, ADD16 was a strong predictor. Latitude had a near linear effect on first flights, whereas longitude produced a generally less-clear effect on all responses. Aphids that are anholocyclic (permanently parthenogenetic) or are monoecious (non-host-alternating) were

  6. Long-term phenological trends, species accumulation rates, aphid traits and climate: five decades of change in migrating aphids.

    PubMed

    Bell, James R; Alderson, Lynda; Izera, Daniela; Kruger, Tracey; Parker, Sue; Pickup, Jon; Shortall, Chris R; Taylor, Mark S; Verrier, Paul; Harrington, Richard

    2015-01-01

    Aphids represent a significant challenge to food production. The Rothamsted Insect Survey (RIS) runs a network of 12·2-m suction-traps throughout the year to collect migrating aphids. In 2014, the RIS celebrated its 50th anniversary. This paper marks that achievement with an extensive spatiotemporal analysis and the provision of the first British annotated checklist of aphids since 1964. Our main aim was to elucidate mechanisms that advance aphid phenology under climate change and explain these using life-history traits. We then highlight emerging pests using accumulation patterns. Linear and nonlinear mixed-effect models estimated the average rate of change per annum and effects of climate on annual counts, first and last flights and length of flight season since 1965. Two climate drivers were used: the accumulated day degrees above 16 °C (ADD16) indicated the potential for migration during the aphid season; the North Atlantic Oscillation (NAO) signalled the severity of the winter before migration took place. All 55 species studied had earlier first flight trends at rate of β = -0·611 ± SE 0·015 days year(-1). Of these species, 49% had earlier last flights, but the average species effect appeared relatively stationary (β = -0·010 ± SE 0·022 days year(-1)). Most species (85%) showed increasing duration of their flight season (β = 0·336 ± SE 0·026 days year(-1)), even though only 54% increased their log annual count (β = 0·002 ± SE <0·001 year(-1)). The ADD16 and NAO were shown to drive patterns in aphid phenology in a spatiotemporal context. Early in the year when the first aphids were migrating, the effect of the winter NAO was highly significant. Further into the year, ADD16 was a strong predictor. Latitude had a near linear effect on first flights, whereas longitude produced a generally less-clear effect on all responses. Aphids that are anholocyclic (permanently parthenogenetic) or are monoecious (non

  7. 24 CFR 206.21 - Interest rate.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... disclosure provisions of 12 CFR part 226 (Truth in Lending) shall constitute full compliance with paragraph... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Interest rate. 206.21 Section 206... CONVERSION MORTGAGE INSURANCE Eligibility; Endorsement Eligible Mortgages § 206.21 Interest rate. (a)...

  8. 24 CFR 206.21 - Interest rate.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... disclosure provisions of 12 CFR part 226 (Truth in Lending) shall constitute full compliance with paragraph... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Interest rate. 206.21 Section 206... CONVERSION MORTGAGE INSURANCE Eligibility; Endorsement Eligible Mortgages § 206.21 Interest rate. (a)...

  9. 7 CFR 3550.66 - Interest rate.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Interest rate. 3550.66 Section 3550.66 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, DEPARTMENT OF AGRICULTURE DIRECT SINGLE FAMILY HOUSING LOANS AND GRANTS Section 502 Origination § 3550.66 Interest rate. Loans will be written using the applicable...

  10. Wearable monitoring for mood recognition in bipolar disorder based on history-dependent long-term heart rate variability analysis.

    PubMed

    Valenza, Gaetano; Nardelli, Mimma; Lanatà, Antonio; Gentili, Claudio; Bertschy, Gilles; Paradiso, Rita; Scilingo, Enzo Pasquale

    2014-09-01

    Current clinical practice in diagnosing patients affected by psychiatric disorders such as bipolar disorder is based only on verbal interviews and scores from specific questionnaires, and no reliable and objective psycho-physiological markers are taken into account. In this paper, we propose to use a wearable system based on a comfortable t-shirt with integrated fabric electrodes and sensors able to acquire electrocardiogram, respirogram, and body posture information in order to detect a pattern of objective physiological parameters to support diagnosis. Moreover, we implemented a novel ad hoc methodology of advanced biosignal processing able to effectively recognize four possible clinical mood states in bipolar patients (i.e., depression, mixed state, hypomania, and euthymia) continuously monitored up to 18 h, using heart rate variability information exclusively. Mood assessment is intended as an intrasubject evaluation in which the patient's states are modeled as a Markov chain, i.e., in the time domain, each mood state refers to the previous one. As validation, eight bipolar patients were monitored collecting and analyzing more than 400 h of autonomic and cardiovascular activity. Experimental results demonstrate that our novel concept of personalized and pervasive monitoring constitutes a viable and robust clinical decision support system for bipolar disorders recognizing mood states with a total classification accuracy up to 95.81%. PMID:24240031

  11. Effects of short- and long-term exposure to ozone on heart rate and blood pressure of emphysematous rats

    SciTech Connect

    Uchiyama, I.; Yokoyama, E.

    1989-02-01

    Electrocardiogram and arterial blood pressure of elastase-treated emphysematous rats (E rats) and saline-treated control rats (S rats) were recorded continuously during exposure to either 1 ppm ozone (O/sub 3/) for 3 hr or 0.5 ppm O/sub 3/ for 6 hr. The heart rates (HRs) of both groups decreased to about 50 and 65% of the initial levels at the end of 1 ppm and 0.5 ppm O/sub 3/ exposure, respectively. Mean arterial blood pressures (MAPs) also decreased to about 76 and 82%, respectively. There was no significant difference in these responses between E and S rats, although the levels of HRs and MAPs of the E rats were always a little lower than those of the S rats. Another group of E and S rats was continuously exposed to 0.2 ppm O/sub 3/ for 4 weeks. The HRs of both E and S groups decreased to about 81 and 88% of the initial levels on the first day, respectively, although they recovered completely by the third day. No significant difference in the variation of HRs during exposure was noted between E and S rats. However, the HR responses of these rats to a challenge exposure of 0.8 ppm O/sub 3/ for 1.5 hr appeared to be different. That is, S rats were more tolerant of the challenge exposure to O/sub 3/ for 1.5 hr than the E rats.

  12. The Long-Term Effective Rate of Different Branches of Idiopathic Trigeminal Neuralgia After Single Radiofrequency Thermocoagulation: A Cohort Study.

    PubMed

    Tang, Yuan-Zhang; Wu, Bai-Shan; Yang, Li-Qiang; Yue, Jian-Ning; He, Liang-Liang; Li, Na; Ni, Jia-Xiang

    2015-11-01

    To evaluate the efficacy of computed tomography (CT) guided single radiofrequency thermocoagualtion (RFT) in 1137 patients with idiopathic trigeminal neuralgia after a follow-up period of 11 years, specially focused on duration of pain relief in different branches of trigeminal nerve, side effect, and complications. Retrospective study of patients with idiopathic trigeminal neuralgia treated with a single CT guided RFT procedure between January 2002 and December 2013. The mean follow-up time was 46.14 ± 30.91 months. Immediate postprocedure pain relief was 98.4%. V2 division obtained the best pain relief rate: 91%, 89%, 80%, 72%, 60%, and 54% at 1, 3, 5, 7, 9, and 11 years, respectively. No statistical difference pairwise comparison was in other groups. The complications included masseter muscle weakness, corneitis, diplopia, ptosis, hearing loss, limited mouth opening, and low pressure headache. Masticatory weakness mostly occurred in patients with V3 branch involvement, while Corneitis and Diplopia all in patients with V1 branch involvement. No mortalities observed during or after RFT. All different branches division of trigeminal neuralgia achieved comparable satisfactory curative effect; V2 obtained the best excellent pain relief, after RFT procedure. Facial numbness is inevitable after RFT, which patients who have pain in all 3 trigeminal divisions and patients who desire no facial numbness should be cautious. Masticatory weakness is mainly related with V3 injured, while Corneitis and Diplopia in patients with V1 injured by RFT. PMID:26559288

  13. 7 CFR 1779.33 - Interest rates.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... will be negotiated between the lender and the borrower. They may be either fixed or variable rates... course of business and are subject to Agency review and approval. (b) Variable rate publication. A variable interest rate must be tied to a base rate published periodically in a recognized national...

  14. 7 CFR 1779.33 - Interest rates.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... will be negotiated between the lender and the borrower. They may be either fixed or variable rates... course of business and are subject to Agency review and approval. (b) Variable rate publication. A variable interest rate must be tied to a base rate published periodically in a recognized national...

  15. Blood pressure and heart rate effects, weight loss and maintenance during long-term phentermine pharmacotherapy for obesity.

    PubMed

    Hendricks, Ed J; Greenway, Frank L; Westman, Eric C; Gupta, Alok K

    2011-12-01

    There is a perception that phentermine pharmacotherapy for obesity increases blood pressure and heart rate (HR), exposing treated patients to increased cardiovascular risk. We collected data from phentermine-treated (PT) and phentermine-untreated (P0) patients at a private weight management practice, to examine blood pressure, HR, and weight changes. Records of 300 sequential returning patients were selected who had been treated with a low-carbohydrate ketogenic diet if their records included complete weight, blood pressure, and HR data from seven office examinations during the first 12 weeks of therapy. The mean time in therapy, time range, and mode was 92 (97.0), 12-624, and 52 weeks. 14% were normotensive, 52% were prehypertensive, and 34% were hypertensive at their first visit or had a previous diagnosis of hypertension. PT subjects systolic blood pressure/diastolic blood pressure (SBP/DBP) declined from baseline at all data points (SBP/DBP -6.9/-5.0 mm Hg at 26, and -7.3/-5.4 at 52 weeks). P0 subjects' declines of SBP/DBP at both 26 and 52 weeks were -8.9/-6.3 but the difference from the treated cohort was not significant. HR changes in treated/untreated subjects at weeks 26 (-0.9/-3.5) and 52 (+1.2/-3.6) were not significant. Weight loss was significantly greater in the PT cohort for week 1 through 104 (P = 0.0144). These data suggest phentermine treatment for obesity does not result in increased SBP, DBP, or HR, and that weight loss assisted with phentermine treatment is associated with favorable shifts in categorical blood pressure and retardation of progression to hypertension in obese patients. PMID:21527891

  16. Updated Long Term Fault Slip Rates and Seismic Hazard in the Central Alborz, Iran: New Constraints From InSAR and GPS

    NASA Astrophysics Data System (ADS)

    Weston, J. M.; Shirzaei, M.

    2015-12-01

    The Alborz mountain range, located south of the Caspian Sea, accommodates 30% of the 25 mm/yr convergence between Arabia and Eurasia. The resulting shortening and left lateral motion is distributed over several active fault zones within the Central Alborz. Despite earlier efforts using only GPS data, little is known about the long term rate of vertical deformation and aseismic slip. Several historical earthquakes have affected this region, some of the largest of these events occurred on the Mosha fault which is close to the capital city, Tehran, which has a population of over eight million. Thus, constraining the interseismic slip rates in this region is particularly important. In this study we complement existing horizontal velocities from a regional GPS network, with line of sight velocities from interferometric synthetic aperture radar (InSAR), to provide additional constraints on the vertical deformation and enhance the spatial coverage. Assuming a seismogenic depth of 30 km, based on microseismicity data, we solve for the geometry and long term slip rates on four major fault strands in this region. We obtain a long term slip rate of ~ 3 mm/yr for the Mosha and North Alborz faults, and ~ 10 mm/yr for the Khazar fault and Parchin faults. These rates and fault geometries are in agreement with earlier works, and fit the GPS data well. However, close to the fault traces there are large residuals in the InSAR data, suggesting that there is shallow creep (< 30 km). Therefore, we carry out a subsequent inversion using only the residual InSAR displacements to solve for the distribution of creep within the seismogenic zones on these faults. We find that the Mosha and North Alborz faults remain locked between 0 - 30 km depth, whilst the Parchin and Khazar faults are creeping. This new observation of fault creep has direct implications for the seismic hazard in the region. On the Mosha fault we estimate a slip deficit equivalent to a Mw 7.0 event. The combination of In

  17. Long-term effects of different type and rates of organic amendments on reclamation of copper mine tailing in Central Chile.

    NASA Astrophysics Data System (ADS)

    Arellano, Eduardo; Garreton, Bruna; Ginocchio, Rosanna

    2016-04-01

    A study was conducted to evaluate the long-term effects of a single application of organic amendments on a copper mine tailings. Seven years after seeding of a mix of herbaceous plant and planting of ten native trees, and the application of organic amendment, plant community and soil fertility was measured in replicated plots that received six different treatments of waste water treatment plant biosolids (100 ton/ha, and 200 ton/ha), olive oil waste (100 ton/ha, and 200 ton/ha) and pisco grapes waste (90 ton/ha, and 200 ton/ha). A control treatment that received no organic amendment was also measured after seven years. Field measurements demonstrated that application of biosolids and pisco grapes waste, at both rates significantly improved vegetation coverage in comparison to the control treatment (80 and 100% vs control, 25%). The high rates of pisco waste had the highest vegetation diversity and survival in comparison to the other treatments. The high rate of olive oil waste had a negative effect on vegetation development in comparison to the control treatment. The application of organic amendment improved soil fertility in the long-term. All the treatments had a significant higher nitrogen concentration in comparison to the control treatment. The high rates of biosolids and pisco grape waste had a significantly effect of soil carbon concentration. Soil macro-aggregate in the high rate of pisco grape waste were also higher than the control, showing a positive relation between soil recover and vegetation development. We can conclude assisted phytostabilization of mine tailings is likely a technically effective solution for the valorisation of organic residues.

  18. A new method for estimating bedrock surface exposure ages and long-term erosion rates using a single in situ-produced cosmogenic radionuclide

    SciTech Connect

    Lifton, N.A.; Jull, A.J.T. . Dept. of Geosciences)

    1993-04-01

    Numerous ambiguities, limitations and uncertainties in geomorphic research have resulted from a historical inability to reliably and quantitatively estimate (1) the age of exposure of a geomorphic surface, and (2) spatial variability of long-term erosion rates. Radioactive and stable nuclides produced in situ by cosmic ray bombardment of rock materials exposed at the earth's surface may enable one to estimate surface exposure ages and long-term erosion rates directly. Recent development of techniques for measuring and interpreting concentrations of these nuclides may ultimately help to resolve many long-standing geomorphic debates. Cosmogenic radionuclide pairs such as [sup 10]Be and [sup 26]Al have been used most frequently to solve the governing equations for both erosion rates and surface exposure ages. However, the applicability of these techniques to geomorphic problems has been limited to some extent by the number of assumptions which had to be made to interpret the measured concentrations -- particularly those pertaining to steady-state or non-steady-state erosion conditions. The authors are developing a new method for interpreting the depth distribution of a single cosmogenic radionuclide in bedrock which avoids the need for many of these assumptions. Monte Carlo techniques are used to explore the range of erosion rate and exposure age conditions on a grid which would produce theoretical depth distributions of the radionuclide consistent with the measured depth profile. They plan to present new cosmogenic [sup 14]C data to corroborate the model results. Although unanswered questions and potential problems remain, this method appears to hold great promise for unraveling spatial variation in both erosion rates and exposure ages of a wide range of bedrock surfaces.

  19. Evaluating release alternatives for a long-lived bird species under uncertainty about long-term demographic rates

    USGS Publications Warehouse

    Moore, Clinton T.; Converse, Sarah J.; Folk, Martin J.; Runge, Michael C.; Nesbitt, Stephen A.

    2012-01-01

    The release of animals to reestablish an extirpated population is a decision problem that is often attended by considerable uncertainty about the probability of success. Annual releases of captive-reared juvenile Whooping Cranes (Grus americana) were begun in 1993 in central Florida, USA, to establish a breeding, non-migratory population. Over a 12-year period, 286 birds were released, but by 2004, the introduced flock had produced only four wild-fledged birds. Consequently, releases were halted over managers' concerns about the performance of the released flock and uncertainty about the efficacy of further releases. We used data on marked, released birds to develop predictive models for addressing whether releases should be resumed, and if so, under what schedule. To examine the outcome of different release scenarios, we simulated the survival and productivity of individual female birds under a baseline model that recognized age and breeding-class structure and which incorporated empirically estimated stochastic elements. As data on wild-fledged birds from captive-reared parents were sparse, a key uncertainty that confronts release decision-making is whether captive-reared birds and their offspring share the same vital rates. Therefore, we used data on the only population of wild Whooping Cranes in existence to construct two alternatives to the baseline model. The probability of population persistence was highly sensitive to the choice of these three models. Under the baseline model, extirpation of the population was nearly certain under any scenario of resumed releases. In contrast, the model based on estimates from wild birds projected a high probability of persistence under any release scenario, including cessation of releases. Therefore, belief in either of these models suggests that further releases are an ineffective use of resources. In the third model, which simulated a population Allee effect, population persistence was sensitive to the release decision

  20. Long-Term Data Reveal a Population Decline of the Tropical Lizard Anolis apletophallus, and a Negative Affect of El Nino Years on Population Growth Rate

    PubMed Central

    Stapley, Jessica; Garcia, Milton; Andrews, Robin M.

    2015-01-01

    Climate change threatens biodiversity worldwide, however predicting how particular species will respond is difficult because climate varies spatially, complex factors regulate population abundance, and species vary in their susceptibility to climate change. Studies need to incorporate these factors with long-term data in order to link climate change to population abundance. We used 40 years of lizard abundance data and local climate data from Barro Colorado Island to ask how climate, total lizard abundance and cohort-specific abundance have changed over time, and how total and cohort-specific abundance relate to climate variables including those predicted to make the species vulnerable to climate change (i.e. temperatures exceeding preferred body temperature). We documented a decrease in lizard abundance over the last 40 years, and changes in the local climate. Population growth rate was related to the previous years’ southern oscillation index; increasing following cooler-wetter, la niña years, decreasing following warmer-drier, el nino years. Within-year recruitment was negatively related to rainfall and minimum temperature. This study simultaneously identified climatic factors driving long-term population fluctuations and climate variables influencing short-term annual recruitment, both of which may be contributing to the population decline and influence the population’s future persistence. PMID:25671423

  1. Long-term data reveal a population decline of the tropical lizard Anolis apletophallus, and a negative affect of el nino years on population growth rate.

    PubMed

    Stapley, Jessica; Garcia, Milton; Andrews, Robin M

    2015-01-01

    Climate change threatens biodiversity worldwide, however predicting how particular species will respond is difficult because climate varies spatially, complex factors regulate population abundance, and species vary in their susceptibility to climate change. Studies need to incorporate these factors with long-term data in order to link climate change to population abundance. We used 40 years of lizard abundance data and local climate data from Barro Colorado Island to ask how climate, total lizard abundance and cohort-specific abundance have changed over time, and how total and cohort-specific abundance relate to climate variables including those predicted to make the species vulnerable to climate change (i.e. temperatures exceeding preferred body temperature). We documented a decrease in lizard abundance over the last 40 years, and changes in the local climate. Population growth rate was related to the previous years' southern oscillation index; increasing following cooler-wetter, la niña years, decreasing following warmer-drier, el nino years. Within-year recruitment was negatively related to rainfall and minimum temperature. This study simultaneously identified climatic factors driving long-term population fluctuations and climate variables influencing short-term annual recruitment, both of which may be contributing to the population decline and influence the population's future persistence. PMID:25671423

  2. Long-term follow up Helicobacter Pylori reinfection rate after second-line treatment: bismuth-containing quadruple therapy versus moxifloxacin-based triple therapy

    PubMed Central

    2013-01-01

    Background The increasing trend of antibiotic resistance requires effective second-line Helicobacter pylori (H. pylori) treatment in high prevalence area of H. pylori. The aim of our study was to evaluate the reinfection rate of H. pylori after second-line treatment that would determine the long-term follow up effect of the rescue therapy. Methods A total of 648 patients who had failed previous H. pylori eradication on standard triple therapy were randomized into two regimens: 1, esomeprazole (20 mg b.i.d), tripotassium dicitrate bismuthate (300 mg q.i.d), metronidazole (500 mg t.i.d), and tetracycline (500 mg q.i.d) (EBMT) or 2, moxifloxacin (400 mg q.d.), esomeprazole (20 mg b.i.d), and amoxicillin (1000 mg b.i.d.) (MEA). At four weeks after completion of eradication therapy, H. pylori tests were performed with 13C urea breath test or invasive tests. In patients who maintained continuous H. pylori negativity for the first year after eradication therapy, H. pylori status was assessed every year. For the evaluation of risk factors of reinfection, gender, age, clinical diagnosis, histological atrophic gastritis or intestinal metaplasia were analyzed. Results The recrudescence rate of the EBMT was 1.7% and of the MEA group 3.3% (p = 0.67). The annual reinfection rate of H. pylori of EBMT was found to be 4.45% and the MEA group 6.46%. Univariate analysis (Log-rank test) showed no association with any clinical risk factor for reinfection. Conclusions The long-term reinfection rate of H. pylori stayed low in both of bismuth-containing quadruple therapy and moxifloxacin-based triple therapy; thus reinfection cannot affect the choice of second-line treatment. Trial registration Clinical Trial Registration Number NCT01792700 PMID:24050512

  3. Comparing global-scale topographic and climatic metrics to long-term erosion rates using ArcSwath, an efficient new ArcGIS tool for swath profile analysis

    NASA Astrophysics Data System (ADS)

    Blomqvist, Niclas; Whipp, David

    2016-04-01

    data and the long-term erosion rates shows that 86 of 288 plots (30%) have "good" R2 values (> 0.35) and 135 of 288 (47%) have an "acceptable" R2 value (> 0.2). The "good" and "acceptable" values have been selected on the basis of visual fit to the regression line. The majority of the plots with a "good" correlation value have positive correlations, while 11/86 plots have negative slopes for the regression lines. Interestingly, two topographic profile shapes were clear in swath profiles: Concave-up (e.g., the central-western Himalaya and the northern Bolivian Andes) and concave-down or straight (e.g., the eastern Himalayas and the southern Bolivian Andes). On the orogen scale, the concave-up shape is often related to relatively high precipitation and erosion rates on the slopes of steep topography. The concave-down/straight profiles seem to occur in association of low rainfall and/or erosion rates. Though we cannot say with confidence, the lack of a clear correlation between long-term erosion rates and climate or topography may be due to the difference in their respective timescales as climate can vary over shorter timescales than 105-107 years. In that case, variations between fluvial and glacial erosion may have overprinted the erosional effects of one another.

  4. Extracting factors for interest rate scenarios

    NASA Astrophysics Data System (ADS)

    Molgedey, L.; Galic, E.

    2001-04-01

    Factor based interest rate models are widely used for risk managing purposes, for option pricing and for identifying and capturing yield curve anomalies. The movements of a term structure of interest rates are commonly assumed to be driven by a small number of orthogonal factors such as SHIFT, TWIST and BUTTERFLY (BOW). These factors are usually obtained by a Principal Component Analysis (PCA) of historical bond prices (interest rates). Although PCA diagonalizes the covariance matrix of either the interest rates or the interest rate changes, it does not use both covariance matrices simultaneously. Furthermore higher linear and nonlinear correlations are neglected. These correlations as well as the mean reverting properties of the interest rates become crucial, if one is interested in a longer time horizon (infrequent hedging or trading). We will show that Independent Component Analysis (ICA) is a more appropriate tool than PCA, since ICA uses the covariance matrix of the interest rates as well as the covariance matrix of the interest rate changes simultaneously. Additionally higher linear and nonlinear correlations may be easily incorporated. The resulting factors are uncorrelated for various time delays, approximately independent but nonorthogonal. This is in contrast to the factors obtained from the PCA, which are orthogonal and uncorrelated for identical times only. Although factors from the ICA are nonorthogonal, it is sufficient to consider only a few factors in order to explain most of the variation in the original data. Finally we will present examples that ICA based hedges outperforms PCA based hedges specifically if the portfolio is sensitive to structural changes of the yield curve.

  5. Cortical bone resorption rate in elderly persons: estimates from long-term in vivo measurements of (90)Sr in the skeleton.

    PubMed

    Shagina, N B; Tolstykh, E I; Degteva, M O; Anspaugh, L R; Napier, B A

    2012-01-01

    The rate of cortical bone resorption was assessed from long-term in vivo measurements of (90)Sr content in the skeleton for men aged 50-80 years and for women 0-30 years after menopause. Measurements of (90)Sr were conducted with a whole body counter (WBC) for residents of the Techa Riverside communities (Southern Urals, Russia), who ingested large amounts of (90)Sr as a result of releases of liquid radioactive wastes into the river from the Mayak plutonium facility in early 1950s. The results of this study showed an increase in the rate of cortical bone resorption in both men and women, as based on the use of accidentally ingested (90)Sr as a tracer for bone metabolism. In men there was a continuous gradual increase in the rate of cortical bone resorption after 55 years from 2.8 to 4.5%/year by the age of 75 years. In women, there was a doubled increase in the rate of cortical bone resorption after menopause of up to 6%/year; then the rate remained unchanged for 10-12 years with a subsequent gradual decline down to 5-5.5%/year. Comparison of the rate of cortical bone resorption in men and women older than 55 years showed that women expressed significantly higher levels of cortical bone resorption. PMID:21871673

  6. Cortical bone resorption rate in elderly persons: Estimates from long-term in vivo measurements of 90Sr in the skeleton

    SciTech Connect

    Shagina, N. B.; Tolstykh, E. I.; Degteva, M. O.; Anspaugh, L. R.; Napier, Bruce A.

    2012-06-01

    The rate of cortical bone resorption was assessed from long-term in vivo measurements of 90Sr content in the skeleton for men aged 50-80 years and for women 0-30 years after menopause. Measurements of 90Sr were conducted with a whole body counter for residents of the Techa Riverside communities (Southern Urals, Russia), who ingested large amounts of 90Sr as a result of releases of liquid radioactive wastes into the river from the Mayak plutonium facility in early 1950s. The results of this study showed an increase in the rate of cortical bone resorption in both men and women, as based on the use of accidentally ingested 90Sr as a tracer for bone metabolism. In men there was a continuous gradual increase in the rate of cortical bone resorption after 55 years from 2.8 to 4.5%/year by the age of 75 years. In women, there was a doubled increase in the rate of cortical bone resorption after menopause of up to 6%/year; then the rate remained unchanged for 10-12 years with a subsequent gradual decline down to 5-5.5%/year. Comparison of the rate of cortical bone resorption in men and women older than 55 years showed that women expressed significantly higher levels of cortical bone resorption.

  7. Long-term stability of liquid ionization chambers with regard to their qualification as local reference dosimeters for low dose-rate absorbed dose measurements in water.

    PubMed

    Bahar-Gogani, J; Grindborg, J E; Johansson, B E; Wickman, G

    2001-03-01

    The long-term sensitivity and calibration stability of liquid ionization chambers (LICs) has been studied at a local and a secondary standards dosimetry laboratory over a period of 3 years. The chambers were transported several times by mail between the two laboratories for measurements. The LICs used in this work are designed for absorbed dose measurements in the dose rate region of 0.1-100 mGy min(-1) and have a liquid layer thickness of 1 mm and a sensitive volume of 16.2 mm3. The liquids used as sensitive media in the chambers are mixtures of isooctane (C8H18) and tetramethylsilane (Si(CH3)4) in different proportions (about 2 to 1). Operating at a polarizing voltage of 300 V the leakage current of the chambers was stable and never exceeded 3% of the observable current at a dose rate of about 1 mGy min(-1). The volume sensitivity of the chambers was measured to be of the order of 10(-9) C Gy(-1) mm3. No systematic changes in the absorbed dose to water calibration was observed for any of the chambers during the test period (sigma < 0.2%). Variations in chamber dose response with small changes in the polarizing voltage as well as sensitivity changes with accumulated absorbed dose were also investigated. Measurements showed that the LIC response varies by 0.15% per 1% change in applied voltage around 300 V. No significant change could be observed in the LIC sensitivity after a single absorbed dose of 15 kGy. The results indicate that the LIC can be made to serve as a calibration transfer instrument and a reference detector for absorbed dose to water determinations providing good precision and long-term reproducibility. PMID:11277221

  8. Caregiver Ratings of Long-term Executive Dysfunction and Attention Problems After Early Childhood Traumatic Brain Injury: Family Functioning Is Important

    PubMed Central

    Kurowski, Brad G.; Taylor, H. Gerry; Yeates, Keith Owen; Walz, Nicolay C.; Stancin, Terry; Wade, Shari L.

    2013-01-01

    Objective To evaluate the relationship of family and parenting factors to long-term executive dysfunction and attention problems after early childhood traumatic brain injury (TBI). We hypothesized that the magnitude of executive dysfunction and attention problems would be moderated by family and parenting factors. Design A multicenter, prospective cohort study that included an orthopedic injury (OI) reference group. Setting Three tertiary academic children’s hospital medical centers and one general medical center. Participants Children, ages 3–7 years, hospitalized for OI, moderate TBI, or severe TBI. Methods and Outcome Measurements Parental ratings of family functioning and parenting styles were obtained 18 months after the injury occurred. The main outcome measurements, which were parental ratings of children’s executive function and attention, were performed at least 24 months after the injury occurred (mean, 39 months; range, 25–63 months). Analysis Group comparisons were conducted with use of t-tests, χ2 analysis, analysis of variance, and Pearson and Spearman correlations. Regression analysis was used to examine associations of the outcomes with family functioning and parenting styles and to test moderating effects of these factors on group differences. Results Participants with severe TBI demonstrated increased executive dysfunction and attention problems compared with those who sustained moderate TBI or OI. Lower levels of family dysfunction were associated with better executive function and attention across groups but did not moderate group differences. However, attention deficits after severe TBI were exacerbated under conditions of more permissive parenting relative to attention deficits after OIs. Conclusions Executive function and attention problems persisted on a long-term basis (>24 months) after early childhood TBI, and positive global family functioning and nonpermissive parenting were associated with better outcomes. Better

  9. Who Becomes a Physics Major? A Long-term Longitudinal Study Examining the Roles of Pre-college Beliefs about Physics and Learning Physics, Interest, and Academic Achievement

    NASA Astrophysics Data System (ADS)

    Perkins, Katherine K.; Gratny, Mindy

    2010-10-01

    In this paper, we examine the correlation between students' beliefs upon entering college and their likelihood of continuing on to become a physics major. Since 2004, we have collected CLASS survey and self-reported level-of-interest responses from students in the first-term, introductory calculus-based physics course (N>2500). Here, we conduct a retrospective analysis of students' incoming CLASS scores and level of interest, comparing those students who go on to become physics majors with those who do not. We find the incoming CLASS scores and reported interest of these future physics majors to be substantially higher than the class average, indicating that these students enter their first college course already having quite expert-like beliefs. The comparative differences are much smaller for grades, SAT score, and university predicted-GPA.

  10. Long-term Trends and Confidence in Global Natural Gas Fugitive Emissions Rates Based on δ13C-CH4

    NASA Astrophysics Data System (ADS)

    Schwietzke, S.; Sherwood, O.; Tans, P. P.; Michel, S. E.; Miller, J. B.; Dlugokencky, E. J.; Griffin, W. M.; Bruhwiler, L.

    2014-12-01

    Numerous life cycle assessment (LCA) and field studies have estimated natural gas (NG) fugitive emissions rates (FER) - the fraction of produced NG, mostly CH4, emitted to the atmosphere, unintentionally or by design, during extraction, processing, transport, and distribution - at local, regional, and national scales. In a recent study, we estimated for the first time the global mean FER using long-term (three decades) atmospheric CH4, δ13C-CH4, and C2H6 measurements from global monitoring networks. As a further development, this work investigates the global mean FER uncertainty range (factor of 2) in more detail to increase confidence in the results. The objectives of this research are to (i) estimate probability distribution functions (PDF) of global mean FER, and (ii) identify long-term trends in global fossil fuel (FF) and other CH4 sources. In order to achieve these objectives, global atmospheric δ13C-CH4 measurements since the mid-1980s are analyzed using a box-model of the global CH4 sources and sinks. First, we derive PDFs of the key model parameters including literature isotopic source signatures, atmospheric lifetimes, natural and anthropogenic emissions, and FF hydrocarbon gas composition. Second, a Monte Carlo simulation of the box-model is performed to quantify FER confidence intervals. While our model attributes the majority of increased CH4 levels over the past three decades to microbial sources, FF sources have also increased slightly. However, FER - an indicator of NG life cycle efficiency - has decreased over the same period given the large NG production increase worldwide. Results are most sensitive to global average microbial isotopic signatures (weighted by source strength) and bottom-up estimates of biomass burning emissions, which will be discussed in more detail.

  11. Assessment of individual adaptation to microgravity during long term space flight based on stepwise discriminant analysis of heart rate variability parameters

    NASA Astrophysics Data System (ADS)

    Baevsky, Roman M.; Chernikova, Anna G.; Funtova, Irina I.; Tank, Jens

    2011-12-01

    Optimization of the cardiovascular system under conditions of long term space flight is provided by individual changes of autonomic cardiovascular control. Heart rate variability (HRV) analysis is an easy to use method under these extreme conditions. We tested the hypothesis that individual HRV analysis provides important information for crew health monitoring. HRV data from 14 Russian cosmonauts measured during long term space flights are presented (two times before and after flight, monthly in flight). HRV characteristics in the time and in the frequency domain were calculated. Predefined discriminant function equations obtained in reference groups (L1=-0.112*HR-1.006*SI-0.047*pNN50-0.086*HF; L2=0.140*HR-0.165*SI-1.293*pNN50+0.623*HF) were used to define four functional states. (1) Physiological normal, (2) prenosological, (3) premorbid and (4) pathological. Geometric mean values for the ISS cosmonauts based on L1 and L2 remained within normal ranges. A shift from the physiological normal state to the prenosological functional state during space flight was detected. The functional state assessed by HRV improved during space flight if compared to pre-flight and early post-flight functional states. Analysis of individual cosmonauts showed distinct patterns depending on the pre-flight functional state. Using the developed classification a transition process from the state of physiological normal into a prenosological state or premorbid state during different stages of space flight can be detected for individual Russian cosmonauts. Our approach to an estimation of HR regulatory pattern can be useful for prognostic purposes.

  12. Long-term data archiving

    SciTech Connect

    Moore, David Steven

    2009-01-01

    Long term data archiving has much value for chemists, not only to retain access to research and product development records, but also to enable new developments and new discoveries. There are some recent regulatory requirements (e.g., FDA 21 CFR Part 11), but good science and good business both benefit regardless. A particular example of the benefits of and need for long term data archiving is the management of data from spectroscopic laboratory instruments. The sheer amount of spectroscopic data is increasing at a scary rate, and the pressures to archive come from the expense to create the data (or recreate it if it is lost) as well as its high information content. The goal of long-term data archiving is to save and organize instrument data files as well as any needed meta data (such as sample ID, LIMS information, operator, date, time, instrument conditions, sample type, excitation details, environmental parameters, etc.). This editorial explores the issues involved in long-term data archiving using the example of Raman spectral databases. There are at present several such databases, including common data format libraries and proprietary libraries. However, such databases and libraries should ultimately satisfy stringent criteria for long term data archiving, including readability for long times into the future, robustness to changes in computer hardware and operating systems, and use of public domain data formats. The latter criterion implies the data format should be platform independent and the tools to create the data format should be easily and publicly obtainable or developable. Several examples of attempts at spectral libraries exist, such as the ASTM ANDI format, and the JCAMP-DX format. On the other hand, proprietary library spectra can be exchanged and manipulated using proprietary tools. As the above examples have deficiencies according to the three long term data archiving criteria, Extensible Markup Language (XML; a product of the World Wide Web

  13. Reconstructing shifts in vital rates driven by long-term environmental change: a new demographic method based on readily available data

    PubMed Central

    González, Edgar J; Martorell, Carlos

    2013-01-01

    Frequently, vital rates are driven by directional, long-term environmental changes. Many of these are of great importance, such as land degradation, climate change, and succession. Traditional demographic methods assume a constant or stationary environment, and thus are inappropriate to analyze populations subject to these changes. They also require repeat surveys of the individuals as change unfolds. Methods for reconstructing such lengthy processes are needed. We present a model that, based on a time series of population size structures and densities, reconstructs the impact of directional environmental changes on vital rates. The model uses integral projection models and maximum likelihood to identify the rates that best reconstructs the time series. The procedure was validated with artificial and real data. The former involved simulated species with widely different demographic behaviors. The latter used a chronosequence of populations of an endangered cactus subject to increasing anthropogenic disturbance. In our simulations, the vital rates and their change were always reconstructed accurately. Nevertheless, the model frequently produced alternative results. The use of coarse knowledge of the species' biology (whether vital rates increase or decrease with size or their plausible values) allowed the correct rates to be identified with a 90% success rate. With real data, the model correctly reconstructed the effects of disturbance on vital rates. These effects were previously known from two populations for which demographic data were available. Our procedure seems robust, as the data violated several of the model's assumptions. Thus, time series of size structures and densities contain the necessary information to reconstruct changing vital rates. However, additional biological knowledge may be required to provide reliable results. Because time series of size structures and densities are available for many species or can be rapidly generated, our model can

  14. Long-Term Efficacy and Toxicity of Low-Dose-Rate {sup 125}I Prostate Brachytherapy as Monotherapy in Low-, Intermediate-, and High-Risk Prostate Cancer

    SciTech Connect

    Kittel, Jeffrey A.; Reddy, Chandana A.; Smith, Kristin L.; Stephans, Kevin L.; Tendulkar, Rahul D.; Ulchaker, James; Angermeier, Kenneth; Campbell, Steven; Stephenson, Andrew; Klein, Eric A.; Wilkinson, D. Allan; Ciezki, Jay P.

    2015-07-15

    Purpose/Objectives: To report long-term efficacy and toxicity for a single-institution cohort of patients treated with low-dose-rate prostate brachytherapy permanent implant (PI) monotherapy. Methods and Materials: From 1996 to 2007, 1989 patients with low-risk (61.3%), intermediate-risk (29.8%), high-intermediate-risk (4.5%), and high-risk prostate cancer (4.4%) were treated with PI and followed up prospectively in a registry. All patients were treated with {sup 125}I monotherapy to 144 Gy. Late toxicity was coded retrospectively according to a modified Common Terminology Criteria for Adverse Events 4.0 scale. The rates of biochemical relapse-free survival (bRFS), distant metastasis-free survival (DMFS), overall survival (OS), and prostate cancer–specific mortality (PCSM) were calculated. We identified factors associated with late grade ≥3 genitourinary (GU) and gastrointestinal (GI) toxicity, bRFS, DMFS, OS, PCSM, and incontinence. Results: The median age of the patients was 67 years, and the median overall and prostate-specific antigen follow-up times were 6.8 years and 5.8 years, respectively. The overall 5-year rates for bRFS, DMFS, OS, and PCSM were 91.9%, 97.8%, 93.7%, and 0.71%, respectively. The 10-year rates were 81.5%, 91.5%, 76.1%, and 2.5%, respectively. The overall rates of late grade ≥3 GU and GI toxicity were 7.6% and 0.8%, respectively. On multivariable analysis, age and prostate length were significantly associated with increased risk of late grade ≥3 GU toxicity. The risk of incontinence was highly correlated with both pre-PI and post-PI transurethral resection of the prostate. Conclusions: Prostate brachytherapy as monotherapy is an effective treatment for low-risk and low-intermediate-risk prostate cancer and appears promising as a treatment for high-intermediate-risk and high-risk prostate cancer. Significant long-term toxicities are rare when brachytherapy is performed as monotherapy.

  15. Assessment of application-rate dependent effects of a long-term fire retardant chemical (Fire Trol 934) on Typha domingensis germination.

    PubMed

    Angeler, David G; Rodríguez, Marta; Martín, Silvia; Moreno, José M

    2004-05-01

    Although long-term fire retardants (LTR) gain increasingly acceptance as effective tools for wildfire management, recent studies indicate their potential harmfulness in the environment, especially in aquatic ecosystems. This study comprises a first laboratory impact assessment of LTR action in temporal Mediterranean wetlands, using seed germination of Typha domingensis as indicator of impact. Our aim was to identify application rates upon which seed germination could be significantly affected. We tested for low (1 l m(-2)) and high (3 l m(-2)) application rates of Fire Trol 934 which are recommended by the manufacturers as a function of fuel characteristics. In addition, we simulated the impact of a higher application rate of 5 l m(-2) because inhomogeneous dispersal of the LTR during fire control and prevention operations can result in locally elevated applications. Results of a microcosm experiment indicate that application rates of 1 or 3 l m(-2) can impact Typha germination rates in the short-term via indirect LTR-mediated effects on water quality, which suppressed necessary cues for germination. However, a subsequent experiment with Petri dishes, using seeds isolated from the LTR treated sediments did not show significantly different germination rates between the control and the treatments with application rates of 1 or 3 l m(-2). This suggests that retardant pre-application germination success could be recovered in nature once the retardant is eliminated. By contrast, seeds almost completely failed to germinate in the microcosm experiment and the subsequent Petri dish essay when an application rate of 5 l m(-2) was used. This suggests a critical level upon which Typha seed germination may be perpetually limited. Research should be extended to other plant species to provide fire managers with guidelines for environmentally safe use of LTR in the Mediterranean region. PMID:14987869

  16. Prostate-specific antigen nadir after high-dose-rate brachytherapy predicts long-term survival outcomes in high-risk prostate cancer

    PubMed Central

    Satoh, Takefumi; Ishiyama, Hiromichi; Tabata, Ken-ichi; Komori, Shouko; Sekiguchi, Akane; Ikeda, Masaomi; Kurosaka, Shinji; Fujita, Tetsuo; Kitano, Masashi; Hayakawa, Kazushige; Iwamura, Masatsugu

    2016-01-01

    Purpose To evaluate the prognostic value of prostate-specific antigen nadir (nPSA) after high-dose-rate (HDR) brachytherapy in clinically non-metastatic high-risk prostate cancer patients. Material and methods Data from 216 patients with high-risk or locally advanced prostate cancer who underwent HDR brachytherapy and external beam radiation therapy with long-term androgen deprivation therapy (ADT) between 2003 and 2008 were analyzed. The median prostate-specific antigen (PSA) level at diagnosis was 24 ng/ml (range: 3-338 ng/ml). The clinical stage was T1c-2a in 55 cases (26%), T2b-2c in 48 (22%), T3a in 75 (35%), and T3b-4 in 38 (17%). The mean dose to 90% of the planning target volume was 6.3 Gy/fraction of HDR brachytherapy. After 5 fractions, external beam radiation therapy with 10 fractions of 3 Gy was administered. All patients initially underwent neoadjuvant ADT for at least 6 months, and adjuvant ADT was continued for 36 months. The median follow-up was 7 years from the start of radiotherapy. Results The 7-year PSA relapse-free rate among patients with a post-radiotherapy nPSA level of ≤ 0.02 ng/ml was 94%, compared with 23% for patients with higher nPSA values (HR = 28.57; 95% CI: 12.04-66.66; p < 0.001). Multivariate analysis revealed that the nPSA value after radiotherapy was a significant independent predictor of biochemical failure, whereas pretreatment predictive values for worse biochemical control including higher level of initial PSA, Gleason score ≥ 8, positive biopsy core rate ≥ 67%, and T3b-T4, failed to reach independent predictor status. The 7-year cancer-specific survival rate among patients with a post-radiotherapy nPSA level of ≤ 0.02 ng/ml was 99%, compared with 82% for patients with higher nPSA values (HR = 32.25; 95% CI: 3.401-333.3; p = 0.002). Conclusions A post-radiotherapy nPSA value of ≤ 0.02 ng/ml was associated with better long-term biochemical tumor control even if patients had pretreatment predictive values for worse

  17. The fate of 5N-nitrate in mesocosms from five European peatlands differing in long-term nitrogen deposition rate

    NASA Astrophysics Data System (ADS)

    Zając, K.; Blodau, C.

    2015-10-01

    Elevated nitrogen (N) deposition changes the retention, transformation, and fluxes of N in ombrotrophic peatlands. To evaluate such effects we applied a 15N tracer (NH415NO3) at a rate of 2.3 g N m-2 yr-1 to mesocosms of five European peatlands with differing long-term N deposition rates for a period of 76 days of dry and 90 days of wet conditions. We determined background N content and moss length growth, and recovered the 15N tracer from the mosses, graminoids, shrubs, the peat, and dissolved N. Background N contents in Sphagnum mosses increased from 5.5 (Degerö Stormyr, deposition < 0.2 g N m-2 yr-1) up to 12.2 mg g-1 (Frölichshaier Sattelmoor, 4.7-6.0 g N m-2 yr-1). In peat from Degerö nitrate and ammonium concentrations were below 3 mg L-1, whereas up to 30 mg L-1 (nitrate) and 11 mg L-1 (ammonium) was found in peat from Frölichshaier Sattelmoor. Sphagnum mosses (down to 5 cm below surface) generally intercepted large amounts of 15N (0.2-0.35 mg g-1) and retained the tracer most effectively relative to their biomass. Similar quantities of the 15N were recovered from the peat, followed by shrubs, graminoids and the dissolved pool. At the most polluted sites we recovered more 15N from shrubs (up to 12.4 %) and from nitrate and ammonium (up to 0.7 %). However, no impact of N deposition on 15N retention by Sphagnum could be identified and their length growth was highest under high N background deposition. Our experiment suggests that the decline in N retention at levels above ca. 1.5 g m-2 yr-1, as expressed by elevated near-surface peat N content and increased dissolved N concentrations, is likely more modest than previously thought. This conclusion is related to the finding that Sphagnum species can apparently thrive at elevated long-term N deposition rates in European peatlands.

  18. The fate of 15N-nitrate in mesocosms from five European peatlands differing in long-term nitrogen deposition rate

    NASA Astrophysics Data System (ADS)

    Zając, K.; Blodau, C.

    2016-02-01

    Elevated nitrogen (N) deposition changes the retention, transformation, and fluxes of N in ombrotrophic peatlands. To evaluate such effects we applied a 15N tracer (NH4 15NO3) at a rate of 2.3 g N m-2 yr-1 to mesocosms of five European peatlands with differing long-term N deposition rates for a period of 76 days of dry and 90 days of wet conditions. We determined background N content and moss length growth, and recovered the 15N tracer from the mosses, graminoids, shrubs, the peat, and dissolved N. Background N contents in Sphagnum mosses increased from 5.5 (Degerö Stormyr, deposition < 0.2 g N m-2 yr-1) up to 12.2 mg g-1 (Frölichshaier Sattelmoor, 4.7-6.0 g N m-2 yr-1). In peat from Degerö, nitrate and ammonium concentrations were below 3 mg L-1, whereas up to 30 (nitrate) and 11 mg L-1 (ammonium) was found in peat from Frölichshaier Sattelmoor. Sphagnum mosses (down to 5 cm below surface) generally intercepted large amounts of 15N (0.2-0.35 mg g-1) and retained the tracer most effectively relative to their biomass. Similar quantities of the 15N were recovered from the peat, followed by shrubs, graminoids, and the dissolved pool. At the most polluted sites we recovered more 15N from shrubs (up to 12.4 %) and from nitrate and ammonium (up to 0.7 %). However, no impact of N deposition on 15N retention by Sphagnum could be identified and their length growth was highest under high N background deposition. Our experiment suggests that the decline in N retention at levels above ca. 1.5 g m-2 yr-1, as expressed by elevated near-surface peat N content and increased dissolved N concentrations, is likely more modest than previously thought. This conclusion is related to the finding that Sphagnum species can apparently thrive at elevated long-term N deposition rates in European peatlands.

  19. Annual Rates on Seismogenic Italian Sources with Models of Long-Term Predictability for the Time-Dependent Seismic Hazard Assessment In Italy

    NASA Astrophysics Data System (ADS)

    Murru, Maura; Falcone, Giuseppe; Console, Rodolfo

    2016-04-01

    The present study is carried out in the framework of the Center for Seismic Hazard (CPS) INGV, under the agreement signed in 2015 with the Department of Civil Protection for developing a new model of seismic hazard of the country that can update the current reference (MPS04-S1; zonesismiche.mi.ingv.it and esse1.mi.ingv.it) released between 2004 and 2006. In this initiative, we participate with the Long-Term Stress Transfer (LTST) Model to provide the annual occurrence rate of a seismic event on the entire Italian territory, from a Mw4.5 minimum magnitude, considering bins of 0.1 magnitude units on geographical cells of 0.1° x 0.1°. Our methodology is based on the fusion of a statistical time-dependent renewal model (Brownian Passage Time, BPT, Matthews at al., 2002) with a physical model which considers the permanent effect in terms of stress that undergoes a seismogenic source in result of the earthquakes that occur on surrounding sources. For each considered catalog (historical, instrumental and individual seismogenic sources) we determined a distinct rate value for each cell of 0.1° x 0.1° for the next 50 yrs. If the cell falls within one of the sources in question, we adopted the respective value of rate, which is referred only to the magnitude of the event characteristic. This value of rate is divided by the number of grid cells that fall on the horizontal projection of the source. If instead the cells fall outside of any seismic source we considered the average value of the rate obtained from the historical and the instrumental catalog, using the method of Frankel (1995). The annual occurrence rate was computed for any of the three considered distributions (Poisson, BPT and BPT with inclusion of stress transfer).

  20. Long-term reliability of single-crystal silicon thin films: the influence of environment on the fatigue damage accumulation rate

    NASA Astrophysics Data System (ADS)

    Pierron, Olivier N., II; Muhlstein, Christopher L.

    2004-12-01

    Single-crystal silicon thin films were forced to resonate at high frequency (~40 kHz) in different environments to study the long-term durability of this structural material used in microelectromechanical (MEMS) devices. The fatigue characterization structure consists of a notched cantilever beam attached to a plate shaped mass and is actuated at resonance, creating fully reversed, constant amplitude, sinusoidal stresses at the notch root. The dynamic behavior of the resonating structure has been meticulously quantified to allow accurate stress measurements from the knowledge of the driving voltage amplitude and the calculation of the quality factors in air and vacuum. In addition, the change in resonant frequency is periodically monitored for long-life specimens. Fatigue failure was observed for specimens tested in humid air and medium vacuum. In air, the stress-life (S-N) curve confirms the unique fatigue behavior already attributed to silicon thin films. In vacuum, the strength of the specimens appears to increase, and fatigue failure is delayed. Fracture surface examination reveals distinct features on the fracture surfaces of long-life fatigued specimens, not found in quasistatic failure, that are clear indications of initiation regions. The decrease rate in resonant frequency during cycling is demonstrated to be related to damage accumulation rate, and is strongly sensitive to both stress amplitude and humidity. The different currently proposed mechanisms are discussed in light of this new set of experimental evidence.

  1. Long-term reliability of single-crystal silicon thin films: the influence of environment on the fatigue damage accumulation rate

    NASA Astrophysics Data System (ADS)

    Pierron, Olivier N.; Muhlstein, Christopher L.

    2005-01-01

    Single-crystal silicon thin films were forced to resonate at high frequency (~40 kHz) in different environments to study the long-term durability of this structural material used in microelectromechanical (MEMS) devices. The fatigue characterization structure consists of a notched cantilever beam attached to a plate shaped mass and is actuated at resonance, creating fully reversed, constant amplitude, sinusoidal stresses at the notch root. The dynamic behavior of the resonating structure has been meticulously quantified to allow accurate stress measurements from the knowledge of the driving voltage amplitude and the calculation of the quality factors in air and vacuum. In addition, the change in resonant frequency is periodically monitored for long-life specimens. Fatigue failure was observed for specimens tested in humid air and medium vacuum. In air, the stress-life (S-N) curve confirms the unique fatigue behavior already attributed to silicon thin films. In vacuum, the strength of the specimens appears to increase, and fatigue failure is delayed. Fracture surface examination reveals distinct features on the fracture surfaces of long-life fatigued specimens, not found in quasistatic failure, that are clear indications of initiation regions. The decrease rate in resonant frequency during cycling is demonstrated to be related to damage accumulation rate, and is strongly sensitive to both stress amplitude and humidity. The different currently proposed mechanisms are discussed in light of this new set of experimental evidence.

  2. Single-Fraction High-Dose-Rate Brachytherapy and Hypofractionated External Beam Radiation Therapy in the Treatment of Intermediate-Risk Prostate Cancer - Long Term Results

    SciTech Connect

    Cury, Fabio L.; Duclos, Marie; Aprikian, Armen; Patrocinio, Horacio; Kassouf, Wassim; Shenouda, George; Faria, Sergio; David, Marc; Souhami, Luis

    2012-03-15

    Purpose: We present the long-term results of a cohort of patients with intermediate-risk prostate cancer (PC) treated with single-fraction high-dose-rate brachytherapy (HDRB) combined with hypofractionated external beam radiation therapy (HypoRT). Methods and Materials: Patients were treated exclusively with HDRB and HypoRT. HDRB delivered a dose of 10 Gy to the prostate surface and HypoRT consisted of 50 Gy delivered in 20 daily fractions. The first 121 consecutive patients with a minimum of 2 years posttreatment follow-up were assessed for toxicity and disease control. Results: The median follow-up was 65.2 months. No acute Grade III or higher toxicity was seen. Late Grade II gastrointestinal toxicity was seen in 9 patients (7.4%) and Grade III in 2 (1.6%). Late Grade III genitourinary toxicity was seen in 2 patients (1.6%). After a 24-month follow-up, a rebiopsy was offered to the first 58 consecutively treated patients, and 44 patients agreed with the procedure. Negative biopsies were found in 40 patients (91%). The 5-year biochemical relapse-free survival rate was 90.7% (95% CI, 84.5-96.9%), with 13 patients presenting biochemical failure. Among them, 9 were diagnosed with distant metastasis. Prostate cancer-specific and overall survival rates at 5 years were 100% and 98.8% (95% CI, 96.4-100%), respectively. Conclusion: The combination of HDRB and HypoRT is well tolerated, with acceptable toxicity rates. Furthermore, results from rebiopsies revealed an encouraging rate of local control. These results confirm that the use of conformal RT techniques, adapted to specific biological tumor characteristics, have the potential to improve the therapeutic ratio in intermediate-risk PC patients.

  3. 7 CFR 4279.125 - Interest rates.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 15 2012-01-01 2012-01-01 false Interest rates. 4279.125 Section 4279.125 Agriculture Regulations of the Department of Agriculture (Continued) RURAL BUSINESS-COOPERATIVE SERVICE AND RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE GUARANTEED LOANMAKING Business and Industry Loans §...

  4. 7 CFR 4279.125 - Interest rates.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 15 2014-01-01 2014-01-01 false Interest rates. 4279.125 Section 4279.125 Agriculture Regulations of the Department of Agriculture (Continued) RURAL BUSINESS-COOPERATIVE SERVICE AND RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE GUARANTEED LOANMAKING Business and Industry Loans §...

  5. 7 CFR 4279.125 - Interest rates.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 15 2013-01-01 2013-01-01 false Interest rates. 4279.125 Section 4279.125 Agriculture Regulations of the Department of Agriculture (Continued) RURAL BUSINESS-COOPERATIVE SERVICE AND RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE GUARANTEED LOANMAKING Business and Industry Loans §...

  6. 7 CFR 1980.320 - Interest rate.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 14 2014-01-01 2014-01-01 false Interest rate. 1980.320 Section 1980.320 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE (CONTINUED) PROGRAM REGULATIONS (CONTINUED) GENERAL...

  7. 7 CFR 4279.231 - Interest rates.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 15 2014-01-01 2014-01-01 false Interest rates. 4279.231 Section 4279.231 Agriculture Regulations of the Department of Agriculture (Continued) RURAL BUSINESS-COOPERATIVE SERVICE AND RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE GUARANTEED LOANMAKING Biorefinery Assistance Loans §...

  8. 7 CFR 4279.231 - Interest rates.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 15 2012-01-01 2012-01-01 false Interest rates. 4279.231 Section 4279.231 Agriculture Regulations of the Department of Agriculture (Continued) RURAL BUSINESS-COOPERATIVE SERVICE AND RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE GUARANTEED LOANMAKING Biorefinery Assistance Loans §...

  9. 7 CFR 4279.231 - Interest rates.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 15 2013-01-01 2013-01-01 false Interest rates. 4279.231 Section 4279.231 Agriculture Regulations of the Department of Agriculture (Continued) RURAL BUSINESS-COOPERATIVE SERVICE AND RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE GUARANTEED LOANMAKING Biorefinery Assistance Loans §...

  10. 76 FR 16570 - Interest Rate Risk

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-24

    ... the credit union's business strategies and should reflect the board's risk tolerance, taking into... and sound IRR program. If possible, separation of those responsible for the risk taking and risk... ADMINISTRATION 12 CFR Part 741 RIN 3133-AD66 Interest Rate Risk AGENCY: National Credit Union...