Science.gov

Sample records for longitudinal practical measurement

  1. Improving Clinical Practice Using a Novel Engagement Approach: Measurement, Benchmarking and Feedback, A Longitudinal Study

    PubMed Central

    Peabody, John W.; Paculdo, David R.; Tamondong-Lachica, Diana; Florentino, Jhiedon; Ouenes, Othman; Shimkhada, Riti; DeMaria, Lisa; Burgon, Trever B.

    2016-01-01

    Background Poor clinical outcomes are caused by multiple factors such as disease progression, patient behavior, and structural elements of care. One other important factor that affects outcome is the quality of care delivered by a provider at the bedside. Guidelines and pathways have been developed with the promise of advancing evidence-based practice. Yet, these alone have shown mixed results or fallen short in increasing adherence to quality of care. Thus, effective, novel tools are required for sustainable practice change and raising the quality of care. Methods The study focused on benchmarking and measuring variation and improving care quality for common types of breast cancer at four sites across the United States, using a set of 12 Clinical Performance and Value® (CPV®) vignettes per site. The vignettes simulated online cases that replicate a typical visit by a patient as the tool to engage breast cancer providers and to identify and assess variation in adherence to evidence-based practice guidelines and pathways. Results Following multiple rounds of CPV measurement, benchmarking and feedback, we found that scores had increased significantly between the baseline round and the final round (P < 0.001) overall and for all domains. By round 4 of the study, the overall score increased by 14% (P < 0.001), and the diagnosis with treatment plan domain had an increase of 12% (P < 0.001) versus baseline. Conclusion We found that serially engaging breast cancer providers with a validated clinical practice engagement and measurement tool, the CPVs, markedly increased quality scores and adherence to clinical guidelines in the simulated patients. CPVs were able to measure differences in clinical skill improvement and detect how fast improvements were made. PMID:27540436

  2. Optical dissector for longitudinal beam profile measurement

    NASA Astrophysics Data System (ADS)

    Zinin, E. I.; Meshkov, O. I.

    2015-10-01

    Experimental study of beam profile dynamics at circular accelerator was carried out due to creation of the sources of synchrotron radiation and colliders, at which the beam consists of several tens or hundreds of bunches distributed over the separatrices. Dynamics of a longitudinal profile of separate bunches was studied by means of streak cameras, however, they are not applied for regular, permanent diagnostics unlike beam position monitors or CCD cameras Streak cameras are very good for study of single processes, not for routine accelerator performance. BINP SB RAS has developed the optical analyzer on the basis of LI-602 dissector which was used for studying the beam dynamics at VEPP-2, VEPP-3, VEPP-4, electron-positron colliders and other electron circular accelerators: Siberia-2, ESRF, etc The dissector provides permanent measurements of the longitudinal beam profile. Nevertheless, the ultimate temporal resolution of the device is about 20 picoseconds Now it is not enough for application at modern accelerators. In this paper we describe the first experimental results obtained with the dissector of the next generation. The measured technical resolution of this device is about 2 picoseconds, but we believe that this value can be improved.

  3. Measurement Practice Guide

    ERIC Educational Resources Information Center

    College and Career Readiness and Success Center, 2014

    2014-01-01

    This discussion guide is part of a larger practice guide designed to help state education agencies (SEAs) define measurement goals, select college and career readiness measures and indicators designed to support those goals, and use the data gathered with those measures and indicators to make informed decisions about college and career readiness…

  4. Task analysis revisited: refining the phlebotomy technician scope of practice and assessing longitudinal change in competencies.

    PubMed

    Fidler, James R

    2007-06-01

    A random sample of 500 phlebotomy technicians certified by a national organization was queried regarding perceptions of importance of 53 specific practice-related tasks representative of various departmental areas. The sample was surveyed via a mail questionnaire. Role centrality was assessed by considering mean importance ratings and by applying the Rasch measurement model to assigned importance ratings. Approximately 36% of the questionnaires received by respondents were returned. The results revealed which tasks were fundamental to the phlebotomy technician scope of practice. To assess longitudinal change in core duties, task saliency was considered with respect to similar data collected a decade earlier. Task importance may be considered by agencies that educate, credential, or employ phlebotomy technicians in providing current job function descriptions. The longitudinal methodology employed may be applicable to other job roles for which the assessment of change is of interest. PMID:17476028

  5. 29. HAWSER DEVICE, DEVELOPED AT WES FOR MEASURING LONGITUDINAL AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    29. HAWSER DEVICE, DEVELOPED AT WES FOR MEASURING LONGITUDINAL AND TRANSVERSE STRESS OF BARGES IN CANAL LOCKS. - Waterways Experiment Station, Hydraulics Laboratory, Halls Ferry Road, 2 miles south of I-20, Vicksburg, Warren County, MS

  6. Longitudinal emittance measurements in the Fermilab Recycler Ring

    SciTech Connect

    C. M. Bhat; John P. Marriner

    2003-06-10

    The Recycler Ring (RR) is a new 8Gev antiproton storage ring at Fermilab. Presently, this machine is being commissioned using protons from the Booster. It uses barrier buckets for stacking, un-stacking and storing the beam. At any given time, the RR is capable of storing proton or antiproton beams in multiple segments azimuthally. These segments of the beam may have widely differing longitudinal emittance and beam intensities and bunch lengths. It is highly essential to be able to measure the longitudinal emittance and keep track of the longitudinal dynamics at various stages of the operation of the RR. In this paper, the authors discuss a few methods of longitudinal emittance measurements in barrier buckets and discuss their merits and demerits

  7. Exploring Intensive Longitudinal Measures of Student Engagement in Blended Learning

    ERIC Educational Resources Information Center

    Henrie, Curtis R.; Bodily, Robert; Manwaring, Kristine C.; Graham, Charles R.

    2015-01-01

    In this exploratory study we used an intensive longitudinal approach to measure student engagement in a blended educational technology course, collecting both self-report and observational data. The self-report measure included a simple survey of Likert-scale and open-ended questions given repeatedly during the semester. Observational data were…

  8. The Feeding Practices and Structure Questionnaire (FPSQ-28): A parsimonious version validated for longitudinal use from 2 to 5 years.

    PubMed

    Jansen, Elena; Williams, Kate E; Mallan, Kimberley M; Nicholson, Jan M; Daniels, Lynne A

    2016-05-01

    Prospective studies and intervention evaluations that examine change over time assume that measurement tools measure the same construct at each occasion. In the area of parent-child feeding practices, longitudinal measurement properties of the questionnaires used are rarely verified. To ascertain that measured change in feeding practices reflects true change rather than change in the assessment, structure, or conceptualisation of the constructs over time, this study examined longitudinal measurement invariance of the Feeding Practices and Structure Questionnaire (FPSQ) subscales (9 constructs; 40 items) across 3 time points. Mothers participating in the NOURISH trial reported their feeding practices when children were aged 2, 3.7, and 5 years (N = 404). Confirmatory Factor Analysis (CFA) within a structural equation modelling framework was used. Comparisons of initial cross-sectional models followed by longitudinal modelling of subscales, resulted in the removal of 12 items, including two redundant or poorly performing subscales. The resulting 28-item FPSQ-28 comprised 7 multi-item subscales: Reward for Behaviour, Reward for Eating, Persuasive Feeding, Overt Restriction, Covert Restriction, Structured Meal Setting and Structured Meal Timing. All subscales showed good fit over 3 time points and each displayed at least partial scalar (thresholds equal) longitudinal measurement invariance. We recommend the use of a separate single item indicator to assess the family meal setting. This is the first study to examine longitudinal measurement invariance in a feeding practices questionnaire. Invariance was established, indicating that the subscales of the shortened FPSQ-28 can be used with mothers to validly assess change in 7 feeding constructs in samples of children aged 2-5 years of age. PMID:26911263

  9. Does a quality management system improve quality in primary care practices in Switzerland? A longitudinal study

    PubMed Central

    Goetz, Katja; Hess, Sigrid; Jossen, Marianne; Huber, Felix; Rosemann, Thomas; Brodowski, Marc; Künzi, Beat; Szecsenyi, Joachim

    2015-01-01

    Objectives To examine the effectiveness of the quality management programme—European Practice Assessment—in primary care in Switzerland. Design Longitudinal study with three points of measurement. Setting Primary care practices in Switzerland. Participants In total, 45 of 91 primary care practices completed European Practice Assessment three times. Outcomes The interval between each assessment was around 36 months. A variance analyses for repeated measurements were performed for all 129 quality indicators from the domains: ‘infrastructure’, ‘information’, ‘finance’, and ‘quality and safety’ to examine changes over time. Results Significant improvements were found in three of four domains: ‘quality and safety’ (F=22.81, p<0.01), ‘information’ (F=27.901, p<0.01) and ‘finance’ (F=4.073, p<0.02). The 129 quality indicators showed a significant improvement within the three points of measurement (F=33.864, p<0.01). Conclusions The European Practice Assessment for primary care practices thus provides a functioning quality management programme, focusing on the sustainable improvement of structural and organisational aspects to promote high quality of primary care. The implementation of a quality management system which also includes a continuous improvement process would give added value to provide good care. PMID:25900466

  10. Longitudinal bunch profile measurements with striplines

    SciTech Connect

    Kramer, S.L.

    1992-01-01

    Striplines beam position monitors are normally considered low frequency devices with at best an octave bandwidth. Some attempts to make them very high frequency and broadband have led to long and complicated tapered construction. However, conventional uniform coupling striplines can provide very high frequency and broadband response, if the downstream induced signal is gated out electronically. In this case, the leading edge beam signal can provide bunch length and even current profile information for bunch lengths shorter than the length of the stripline. Recent improvement in transient digitizers have made these measurements possible for accelerator operations. Measurements of bunch lengths down to 50 psec are results are presented. Improvements to striplines and measurement systems are discussed, that could lead to bunch length resolutions {approx} 10 psec.

  11. Longitudinal bunch profile measurements with striplines

    SciTech Connect

    Kramer, S.L.

    1992-05-01

    Striplines beam position monitors are normally considered low frequency devices with at best an octave bandwidth. Some attempts to make them very high frequency and broadband have led to long and complicated tapered construction. However, conventional uniform coupling striplines can provide very high frequency and broadband response, if the downstream induced signal is gated out electronically. In this case, the leading edge beam signal can provide bunch length and even current profile information for bunch lengths shorter than the length of the stripline. Recent improvement in transient digitizers have made these measurements possible for accelerator operations. Measurements of bunch lengths down to 50 psec are results are presented. Improvements to striplines and measurement systems are discussed, that could lead to bunch length resolutions {approx} 10 psec.

  12. Measurement of longitudinal electron diffusion in liquid argon

    NASA Astrophysics Data System (ADS)

    Li, Yichen; Tsang, Thomas; Thorn, Craig; Qian, Xin; Diwan, Milind; Joshi, Jyoti; Kettell, Steve; Morse, William; Rao, Triveni; Stewart, James; Tang, Wei; Viren, Brett

    2016-04-01

    We report the measurement of longitudinal electron diffusion coefficients in liquid argon for electric fields between 100 and 2000 V/cm with a gold photocathode as a bright electron source. The measurement principle, apparatus, and data analysis are described. In the region between 100 and 350 V/cm, our results show a discrepancy with the previous measurement [1]. In the region between 350 and 2000 V/cm, our results represent the world's best measurement. Over the entire measured electric field range, our results are systematically higher than the calculation of Atrazhev-Timoshkin [2]. The quantum efficiency of the gold photocathode, the drift velocity and longitudinal diffusion coefficients in gas argon are also presented.

  13. [The problem of repeated measurements. Longitudinal analysis in epidemiology].

    PubMed

    Sáez, M

    2001-01-01

    In longitudinal analyses subjects are repeatedly measured along time. They are mixed designs, characterised for their simultaneous consideration of two or more dimensions of analysis, in which time is one of the dimensions.Longitudinal analyses have important advantages with respect other designs. The most important is that they are more efficient, since they allow to distinguish between-individual and within-individual variation.Longitudinal analyses can be approached marginal and conditionally. Whereas the former allows to draw poblational, or average, inferences, the latter permits to draw individual inferences.The statistical models to use depend on the type of response variable. If the dependent variable is normally distributed one will use linear mixed models. When the response is a count one will use mixed Poisson regressions. Mixed binomial or multinomial logistic regressions should be used when the response would be categorical. PMID:11578565

  14. Measurement and simulation of the RHIC abort kicker longitudinal impedence

    SciTech Connect

    Abreu,N.P.; Hahn,H.; Choi, E.

    2009-09-01

    In face of the new upgrades for RHIC the longitudinal impedance of the machine plays an important role in setting the threshold for instabilities and the efficacy of some systems. In this paper we describe the measurement of the longitudinal impedance of the abort kicker for RHIC as well as computer simulations of the structure. The impedance measurement was done by the S{sub 21} wire method covering the frequency range from 9 kHz to 2.5 GHz. We observed a sharp resonance peak around 10 MHz and a broader peak around 20 MHz in both, the real and imaginary part, of the Z/n. These two peaks account for a maximum imaginary longitudinal impedance of j15 {Omega}, a value an order of magnitude larger than the estimated value of j0.2 {Omega}, which indicates that the kicker is one of the main sources of longitudinal impedance in the machine. A computer model was constructed for simulations in the CST MWS program. Results for the magnet input and the also the beam impedance are compared to the measurements. A more detail study of the system properties and possible changes to reduce the coupling impedance are presented.

  15. Recommended Practices in Thrust Measurements

    NASA Technical Reports Server (NTRS)

    Polk, James E.; Pancotti, Anthony; Haag, Thomas; King, Scott; Walker, Mitchell; Blakely, Joseph; Ziemer, John

    2013-01-01

    Accurate, direct measurement of thrust or impulse is one of the most critical elements of electric thruster characterization, and one of the most difficult measurements to make. The American Institute of Aeronautics and Astronautics has started an initiative to develop standards for many important measurement processes in electric propulsion, including thrust measurements. This paper summarizes recommended practices for the design, calibration, and operation of pendulum thrust stands, which are widely recognized as the best approach for measuring micro N- to mN-level thrust and micro Ns-level impulse bits. The fundamentals of pendulum thrust stand operation are reviewed, along with its implementation in hanging pendulum, inverted pendulum, and torsional balance configurations. Methods of calibration and recommendations for calibration processes are presented. Sources of error are identified and methods for data processing and uncertainty analysis are discussed. This review is intended to be the first step toward a recommended practices document to help the community produce high quality thrust measurements.

  16. Integrative data analysis through coordination of measurement and analysis protocol across independent longitudinal studies.

    PubMed

    Hofer, Scott M; Piccinin, Andrea M

    2009-06-01

    Replication of research findings across independent longitudinal studies is essential for a cumulative and innovative developmental science. Meta-analysis of longitudinal studies is often limited by the amount of published information on particular research questions, the complexity of longitudinal designs and the sophistication of analyses, and practical limits on full reporting of results. In many cases, cross-study differences in sample composition and measurements impede or lessen the utility of pooled data analysis. A collaborative, coordinated analysis approach can provide a broad foundation for cumulating scientific knowledge by facilitating efficient analysis of multiple studies in ways that maximize comparability of results and permit evaluation of study differences. The goal of such an approach is to maximize opportunities for replication and extension of findings across longitudinal studies through open access to analysis scripts and output for published results, permitting modification, evaluation, and extension of alternative statistical models and application to additional data sets. Drawing on the cognitive aging literature as an example, the authors articulate some of the challenges of meta-analytic and pooled-data approaches and introduce a coordinated analysis approach as an important avenue for maximizing the comparability, replication, and extension of results from longitudinal studies. PMID:19485626

  17. Integrative Data Analysis through Coordination of Measurement and Analysis Protocol across Independent Longitudinal Studies

    PubMed Central

    Hofer, Scott M.; Piccinin, Andrea M.

    2009-01-01

    Replication of research findings across independent longitudinal studies is essential for a cumulative and innovative developmental science. Meta-analysis of longitudinal studies is often limited by the amount of published information on particular research questions, the complexity of longitudinal designs and sophistication of analyses, and practical limits on full reporting of results. In many cases, cross-study differences in sample composition and measurements impede or lessen the utility of pooled data analysis. A collaborative, coordinated analysis approach can provide a broad foundation for cumulating scientific knowledge by facilitating efficient analysis of multiple studies in ways that maximize comparability of results and permit evaluation of study differences. The goal of such an approach is to maximize opportunities for replication and extension of findings across longitudinal studies through open access to analysis scripts and output for published results, permitting modification, evaluation, and extension of alternative statistical models, and application to additional data sets. Drawing on the cognitive aging literature as an example, we articulate some of the challenges of meta-analytic and pooled-data approaches and introduce a coordinated analysis approach as an important avenue for maximizing the comparability, replication, and extension of results from longitudinal studies. PMID:19485626

  18. Objective Measures for Longitudinal Assessment of Robotic Surgery Training

    PubMed Central

    Kumar, Rajesh; Jog, Amod; Vagvolgyi, Balazs; Nguyen, Hiep; Hager, Gregory; Chen, Chi Chiung Grace; Yuh, David

    2011-01-01

    Objectives Current robotic training approaches lack criteria for automatically assessing and tracking (over time) technical skills separately from clinical proficiency. We describe the development and validation of a novel automated and objective framework for assessment of training. Methods We are able to record all system variables (stereo instrument video, hand and instrument motion, buttons and pedal events) from the da Vinci surgical systems using a portable archival system integrated with the robotic surgical system. Data can be collected unsupervised, and the archival system does not change system operation in any way. Our open-ended multi-center protocol is collecting surgical skill benchmarking data from 24 trainees to surgical proficiency, subject only to their continued availability. Two independent experts performed structured (OSATS) assessments on longitudinal data from 8 novice and 4 expert surgeons to generate ground truth for training and to validate our computerized statistical analysis methods in identifying ranges of operational and clinical skill measures. Results Objective differences in operational and technical skill between known experts and other subjects were quantified. Longitudinal learning curves and statistical analysis for trainee performance measures are reported. Graphical representations of skills developed for feedback to the trainees are also included. Conclusions We describe an open-ended longitudinal study and automated motion recognition system capable of objectively differentiating between clinical and technical operational skills in robotic surgery. Our results demonstrate a convergence of trainee skill parameters towards those derived from expert robotic surgeons over the course of our training protocol. PMID:22172215

  19. Impact of Curriculum on Understanding of Professional Practice: A Longitudinal Study of Students Commencing Dental Education

    ERIC Educational Resources Information Center

    Kieser, Jules A.; Dall'Alba, Gloria; Livingstone, Vicki

    2009-01-01

    This longitudinal study examines changes in understanding of dental practice among a cohort of students in the early years of a dentistry programme. In their first two professional years, we identified five distinct understandings of dental practice that we have ordered from least to most comprehensive: "relieving pain or generally caring for…

  20. Teachers' Changing Practices with Information and Communication Technologies: An Up-Close, Longitudinal Analysis

    ERIC Educational Resources Information Center

    Orlando, Joanne

    2014-01-01

    While digital technology has become a significant resource for contemporary schooling, we still have little understanding of how these resources shape teachers' scholarly practices and what support is needed to improve and move forward. This paper reports on a 5-year qualitative, longitudinal study on the scholarly practices of a small number…

  1. Laser wakefield excitation and measurement by femtosecond longitudinal interferometry

    SciTech Connect

    Siders, C.W.; Le Blanc, S.P.; Fisher, D.; Tajima, T.; Downer, M.C.; Babine, A.; Stepanov, A.; Sergeev, A.

    1996-04-01

    Plasma density oscillations (Langmuir waves) in the wake of an intense (I{sub peak} {approximately} 3 {times} 10{sup 17}W/cm{sup 2}) laser pulse (100 fs) are measured with ultrafast time resolution using a longitudinal interferometric technique. Phase shifts consistent with large amplitude ({delta}n{sub e}/n{sub e} {approximately} 1) density waves at the electron plasma frequency were observed in a fully tunnel-ionized He plasma, corresponding to longitudinal electric fields of {approximately} 10 GV/m. Strong radial ponderomotive forces enhance the density oscillations. As this technique utilizes a necessary component of any laser-based plasma accelerator, it promises to be a powerful tool for on-line monitoring and control of future plasma-based particle accelerators.

  2. First measurement of laser Wakefield oscillations by longitudinal interferometry

    SciTech Connect

    Siders, C.W.; Le Blanc, S.P.; Rau, B.; Fisher, D.; Tajima, T.; Downer, M.C.; Babine, A.; Stepanov, A.; Sergeev, A.

    1996-12-31

    Because the electrostatic fields present in plasma waves can exceed those achievable in conventional accelerators and approach atomic scale values (E{sub a} {approximately} 500 GV/m), plasma based accelerators have received considerable attention as compact sources of high-energy electron pulses. Although stimulated Raman scattering or terahertz radiation at {ital w{sub p}} provided spatially averaged optical signatures of the plasma wave`s existence, new diagnostic techniques are required to map the the temporal and spatial structure of the plasma wave directly since such information is vital for addressing fundamental issues of wakefield generation and propagation. In this paper, we report femtosecond time resolved measurements of the longitudinal and radial structure of laser wakefield oscillations using an all optical technique known as interferometric ``photon acceleration`` or Longitudinal Interferometry.

  3. Measured longitudinal beam impedance of a Tevatron separator

    SciTech Connect

    James L Crisp; Brian J Fellenz

    2002-12-09

    Twenty two separators are currently installed in the Tevatron. The longitudinal impedance of one of these devices was recently measured with a stretched wire. The stretched wire technique can only measure impedance below the cutoff frequency (500MHz). The geometry of a separator is similar to an un-terminated stripline beam position detector. The separator plates occupy a 13.5'' ID vacuum tank, are 101'' long, 7.8'' wide, and have a 2'' gap between them. The differential characteristic impedance between the plates is estimated to be 81 {Gamma} and the common mode impedance plate to ground is about 42 {Gamma}.

  4. Correlating Function and Imaging Measures of the Medial Longitudinal Fasciculus

    PubMed Central

    Sakaie, Ken; Takahashi, Masaya; Remington, Gina; Wang, Xiaofeng; Conger, Amy; Conger, Darrel; Dimitrov, Ivan; Jones, Stephen; Frohman, Ashley; Frohman, Teresa; Sagiyama, Koji; Togao, Osamu

    2016-01-01

    Objective To test the validity of diffusion tensor imaging (DTI) measures of tissue injury by examining such measures in a white matter structure with well-defined function, the medial longitudinal fasciculus (MLF). Injury to the MLF underlies internuclear ophthalmoparesis (INO). Methods 40 MS patients with chronic INO and 15 healthy controls were examined under an IRB-approved protocol. Tissue integrity of the MLF was characterized by DTI parameters: longitudinal diffusivity (LD), transverse diffusivity (TD), mean diffusivity (MD) and fractional anisotropy (FA). Severity of INO was quantified by infrared oculography to measure versional disconjugacy index (VDI). Results LD was significantly lower in patients than in controls in the medulla-pons region of the MLF (p < 0.03). FA was also lower in patients in the same region (p < 0.0004). LD of the medulla-pons region correlated with VDI (R = -0.28, p < 0.05) as did FA in the midbrain section (R = 0.31, p < 0.02). Conclusions This study demonstrates that DTI measures of brain tissue injury can detect injury to a functionally relevant white matter pathway, and that such measures correlate with clinically accepted evaluation indices for INO. The results validate DTI as a useful imaging measure of tissue integrity. PMID:26800522

  5. Parenting Practices and Adolescent Sexual Behavior: A Longitudinal Study

    ERIC Educational Resources Information Center

    Bersamin, Melina; Todd, Michael; Fisher, Deborah A.; Hill, Douglas L.; Grube, Joel W.; Walker, Samantha

    2008-01-01

    The effects of parental attitudes, practices, and television mediation on adolescent sexual behaviors were investigated in a study of adolescent sexuality and media (N = 887). Confirmatory factor analyses supported an eight-factor parenting model with television mediation factors as constructs distinct from general parenting practices. Logistic…

  6. The Role of Practice in Chess: A Longitudinal Study

    ERIC Educational Resources Information Center

    Campitelli, Guillermo; Gobet, Fernand

    2008-01-01

    We investigated the role of practice in the acquisition of chess expertise by submitting a questionnaire to 104 players of different skill levels. Players had to report their chess rating, the number of hours of individual and group practice, their use of different learning resources and activities, and whether they had been trained by a coach.…

  7. Parenting practices and school dropout: a longitudinal study.

    PubMed

    Blondal, Kristjana S; Adalbjarnardottir, Sigrun

    2009-01-01

    Adolescents' perceptions of parenting style and parental involvement in their education were examined longitudinally and related to school dropout among Icelandic youth (N = 427). Results indicated that adolescents who, at age 14, characterized their parents as authoritative (showing acceptance and supervision) were more likely to have completed upper secondary school by age 22 than adolescents from non-authoritative families, controlling for adolescents' gender, socioeconomic status (SES), temperament, and parental involvement. Parenting style seems to more strongly predict school dropout than parental involvement. Further, parenting style may moderate the relationship between parental involvement and dropout, but not in all groups; only in authoritative families does parental involvement decrease the likelihood of school dropout. Furthermore, even after controlling for previous academic achievement, adolescents from authoritative families were less likely to drop out than adolescents from authoritarian and neglectful families. These findings emphasize the importance of encouraging quality parent-child relationships in order to reduce the likelihood of school dropout. PMID:20432598

  8. Teachers developing exemplary inquiry practices: Three longitudinal case studies

    NASA Astrophysics Data System (ADS)

    Sweetman, Sara Berry

    If students are to be successful in the ever-changing scientific world they need to be taught how to think critically, to manipulate materials, and to gather evidence to build knowledge. Most teachers fall short in providing students the inquiry instruction described in the Next Generation Science Frameworks (National Research Council, 2011). This study examined three elementary science teachers' processes as they developed inquiry practices over time. The Electronic Quality of Inquiry Protocol (EQUIP) was used to gather quantitative and qualitative evidence of the teachers' inquiry practices in terms of four factors, Curriculum, Instruction, Discourse, and Assessment. A chronological analysis was used to examine the teachers' professional development and curriculum experiences in relation to their teaching practices. The results showed that all three teachers did change their practice, although the changes varied among cases. For each case, multiple factors influenced the teacher's development. There was a strong positive correlation between the quality of the teachers' inquiry practices and the time spent in curriculum-contextualized professional development. This research indicates that when teachers are supported with curriculum and professional development over extended periods, they develop exemplary inquiry practices. Three recommendations are provided for those interested in implementing science education reform.

  9. Measured longitudinal beam impedance of booster gradient magnets

    SciTech Connect

    James L Crisp and Brian J. Fellenz

    2001-08-24

    The Booster gradient magnets have no vacuum pipe which forces the beam image current to flow along the laminated pole tips. Both D and F style magnets were measured with a stretched wire to determine the longitudinal beam impedance caused by these laminations. Results are compared to calculations done 30 years ago. The inductive part of the magnet impedance is interesting because it partially compensates for the negative inductance effects of space charge on the beam. An R/L circuit consisting of 37K{center_dot} in parallel with between 40 and 100uH is a reasonable approximation to the total impedance of Booster magnet laminations.

  10. Evaluation of thermal gradients in longitudinal spin Seebeck effect measurements

    NASA Astrophysics Data System (ADS)

    Sola, A.; Kuepferling, M.; Basso, V.; Pasquale, M.; Kikkawa, T.; Uchida, K.; Saitoh, E.

    2015-05-01

    In the framework of the longitudinal spin Seebeck effect (LSSE), we developed an experimental setup for the characterization of LSSE devices. This class of device consists in a layered structure formed by a substrate, a ferrimagnetic insulator (YIG) where the spin current is thermally generated, and a paramagnetic metal (Pt) for the detection of the spin current via the inverse spin-Hall effect. In this kind of experiments, the evaluation of a thermal gradient through the thin YIG layer is a crucial point. In this work, we perform an indirect determination of the thermal gradient through the measurement of the heat flux. We developed an experimental setup using Peltier cells that allow us to measure the heat flux through a given sample. In order to test the technique, a standard LSSE device produced at Tohoku University was measured. We find a spin Seebeck SSSE coefficient of 2.8 × 10 - 7 V K-1.

  11. Understanding Changes in Teachers' ICT Practices: A Longitudinal Perspective

    ERIC Educational Resources Information Center

    Orlando, Joanne

    2009-01-01

    With the introduction of Information and Communication Technologies (ICT) into schools came the expectation that teachers would adopt ICT and change their practices in particular ways. Research indicates that teachers have not changed in the ways expected. Suggested in this paper is that limitations in current research methodologies documenting…

  12. Practice and drop-out effects during a 17-year longitudinal study of cognitive aging.

    PubMed

    Rabbitt, Patrick; Diggle, Peter; Holland, Fiona; McInnes, Lynn

    2004-03-01

    Interpretations of longitudinal studies of cognitive aging are misleading unless effects of practice and selective drop-out are considered. A random effects model taking practice and drop-out into account analyzed data from four successive presentations of each of two intelligence tests, two vocabulary tests, and two verbal memory tests during a 17-year longitudinal study of 5,899 community residents whose ages ranged from 49 to 92 years. On intelligence tests, substantial practice effects counteracted true declines observed over 3 to 5 years of aging and remained significant even with intervals of 7 years between successive assessments. Adjustment for practice and drop-out revealed accelerating declines in fluid intelligence and cumulative learning, linear declines in verbal free recall, and no substantial change in vocabulary. Socioeconomic status and basal levels of general fluid ability did not affect rates of decline. After further adjustment for demographics, variability between individuals was seen to increase as the sample aged. PMID:15014091

  13. Making Meaning of Constructivism: A Longitudinal Study of Beginning History Teachers' Beliefs and Practices

    ERIC Educational Resources Information Center

    Martell, Christopher C.

    2012-01-01

    This longitudinal interpretative case study examined the constructivist beliefs and related practices of four secondary history teachers from their teacher preparation through their first year in the classroom. The results of this study showed that issues of historical content knowledge and classroom control were major barriers for the…

  14. A Longitudinal Study of Changes in Marketing Practices at Private Christian Colleges

    ERIC Educational Resources Information Center

    Vander Schee, Brian A.

    2009-01-01

    This article presents the results of a longitudinal study investigating current marketing practices at selected church-related, private, four-year compared to those in place in 1997. The role that institutional selectivity plays in the use of marketing activities was also investigated. The researcher surveyed the admissions directors or enrollment…

  15. Change in University Teachers' Elearning Beliefs and Practices: A Longitudinal Study

    ERIC Educational Resources Information Center

    Scott, Karen M.

    2016-01-01

    Little longitudinal research has examined change in university teachers' elearning beliefs and practices after their initial experience with elearning. This study addresses this gap by focusing on six teachers who developed and implemented an elearning resource, and the changes they made to the resource and its implementation over two years. A…

  16. Maternal Cultural Values and Parenting Practices: Longitudinal Associations with Chinese Adolescents' Aggression

    ERIC Educational Resources Information Center

    Shuster, Michael M.; Li, Yan; Shi, Junqi

    2012-01-01

    Interrelations among cultural values, parenting practices, and adolescent aggression were examined using longitudinal data collected from Chinese adolescents and their mothers. Adolescents' overt and relational aggression were assessed using peer nominations at Time 1 (7th grade) and Time 2 (9th grade). Mothers reported endorsement of cultural…

  17. Building a Constructivist Practice: A Longitudinal Study of Beginning History Teachers

    ERIC Educational Resources Information Center

    Martell, Christopher C.

    2014-01-01

    This longitudinal interpretative case study examined the constructivist beliefs and related practices of four secondary history teachers from their teacher preparation through their first year in the classroom. The results of this study showed that issues of classroom control were major barriers for the implementation of constructivist-oriented…

  18. Preschool Home Literacy Practices and Children's Literacy Development: A Longitudinal Analysis

    ERIC Educational Resources Information Center

    Hood, Michelle; Conlon, Elizabeth; Andrews, Glenda

    2008-01-01

    In this 3-year longitudinal study, the authors tested and extended M. Senechal and J. Le Fevre's (2002) model of the relationships between preschool home literacy practices and children's literacy and language development. Parent-child reading (Home Literacy Environment Questionnaire plus a children's Title Recognition Test) and parental teaching…

  19. A Longitudinal Study of the Relation between Depressive Symptomatology and Parenting Practices

    ERIC Educational Resources Information Center

    Arellano, Paula A. Errazuriz; Harvey, Elizabeth A.; Thakar, Dhara A.

    2012-01-01

    This longitudinal study examined whether mothers' depressive symptomatology predicted parenting practices in a sample of 199 mothers of 3-year-old children with behavior problems who were assessed yearly until age 6. Higher maternal depressive symptoms were associated with higher overreactivity and laxness and lower warmth when children were 6…

  20. Kindergarten Teachers' Use of Developmentally Appropriate Practices: Results from the Early Childhood Longitudinal Study, Kindergarten Class of 1998-1999.

    ERIC Educational Resources Information Center

    Rathbun, Amy H.; Walston, Jill T.; Hausken, Elvira Germino

    This longitudinal study examined the extent to which developmentally appropriate practices of teaching and evaluation are accepted and implemented in primary schools and the relationship of teacher educational background and experience with the use of these practices. Data were obtained from the Early Childhood Longitudinal Study kindergarten…

  1. Practical steps for implementing quality measurement in practice

    PubMed Central

    Wang, David; Cheng, Eric M.; Sanders, Amy E.; Dubinsky, Richard M.

    2014-01-01

    Summary All neurologists must begin incorporating quality measurement and quality improvement into their practice. Efforts to pay physicians based on the quality of their care and patient outcomes moves quality measurement beyond reporting to satisfy regulatory requirements and pushes physicians to select and use quality measures to improve patient outcomes and patient experience. This article provides practical steps and proposes considerations for neurologic practices advancing quality measurement and improvement. PMID:25317379

  2. Evaluation of thermal gradients in longitudinal spin Seebeck effect measurements

    SciTech Connect

    Sola, A. Kuepferling, M.; Basso, V.; Pasquale, M.; Kikkawa, T.; Uchida, K.; Saitoh, E.

    2015-05-07

    In the framework of the longitudinal spin Seebeck effect (LSSE), we developed an experimental setup for the characterization of LSSE devices. This class of device consists in a layered structure formed by a substrate, a ferrimagnetic insulator (YIG) where the spin current is thermally generated, and a paramagnetic metal (Pt) for the detection of the spin current via the inverse spin-Hall effect. In this kind of experiments, the evaluation of a thermal gradient through the thin YIG layer is a crucial point. In this work, we perform an indirect determination of the thermal gradient through the measurement of the heat flux. We developed an experimental setup using Peltier cells that allow us to measure the heat flux through a given sample. In order to test the technique, a standard LSSE device produced at Tohoku University was measured. We find a spin Seebeck S{sub SSE} coefficient of 2.8×10{sup −7} V K{sup −1}.

  3. Measuring Mathematical Knowledge for Teaching: A Longitudinal Study Using Two Measures

    ERIC Educational Resources Information Center

    Copur-Gencturk, Yasemin; Lubienski, Sarah T.

    2013-01-01

    This longitudinal study examines growth in teacher knowledge as measured by two popular assessments--Learning Mathematics for Teaching (LMT) and Diagnostic Teacher Assessments in Mathematics and Science (DTAMS). Using data collected from 24 teachers, we compare the extent to which each assessment captured teacher learning during a K-8 mathematics…

  4. A Longitudinal Study of the Relation Between Depressive Symptomatology and Parenting Practices

    PubMed Central

    Errázuriz, Paula A.; Harvey, Elizabeth A.; Thakar, Dhara A.

    2011-01-01

    This longitudinal study examined whether mothers’ depressive symptomatology predicted parenting practices in a sample of 199 mothers of 3-year-old children with behavior problems who were assessed yearly until age 6. Higher maternal depressive symptoms were associated with higher overreactivity and laxness and lower warmth when children were 6 years old. Higher maternal depressive symptoms were also related to increases in overreactivity across the preschool years. Moreover, depression and parenting practices (overreactivity and laxness) covaried over time within mothers. These results provide evidence of a strong link between maternal depression and parenting during the preschool years. PMID:22611298

  5. Measuring longitudinal myelin water fraction in new multiple sclerosis lesions

    PubMed Central

    Vargas, Wendy S.; Monohan, Elizabeth; Pandya, Sneha; Raj, Ashish; Vartanian, Timothy; Nguyen, Thanh D.; Hurtado Rúa, Sandra M.; Gauthier, Susan A.

    2015-01-01

    Objectives Investigating the potential of myelin repair strategies in multiple sclerosis (MS) requires an understanding of myelin dynamics during lesion evolution. The objective of this study is to longitudinally measure myelin water fraction (MWF), an MRI biomarker of myelin, in new MS lesions and to identify factors that influence their subsequent myelin content. Methods Twenty-three MS patients were scanned with whole-brain Fast Acquisition with Spiral Trajectory and T2prep (FAST-T2) MWF mapping at baseline and median follow-up of 6 months. Eleven healthy controls (HC) confirmed the reproducibility of FAST-T2 in white matter regions of interests (ROIs) similar to a lesion size. A random-effect-model was implemented to determine the association between baseline clinical and lesion variables and the subsequent MWF. Results ROI-based measurements in HCs were highly correlated between scans [mean r = 0.893 (.764–.967)]. In MS patients, 38 gadolinium enhancing (Gd+) and 25 new non-enhancing (Gd−) T2 hyperintense lesions (5.7 months, ±3.8) were identified. Significant improvement in MWF was seen in Gd+ lesions (0.035 ± 0.029, p < 0.001) as compared to Gd− lesions (0.006 ± 0.017, p = 0.065). In the model, a higher baseline MWF (p < 0.001) and the presence of Gd (p < 0.001) were associated with higher subsequent MWF. Conclusions FAST T2 provides a clinically feasible method to quantify MWF in new MS lesions. The observed influence of baseline MWF, which represents a combined effect of both resolving edema and myelin change within acute lesions, suggests that the extent of initial inflammation impacts final myelin recovery. PMID:26594620

  6. Reactivity in Rapidly Collected Hygiene and Toilet Spot Check Measurements: A Cautionary Note for Longitudinal Studies

    PubMed Central

    Arnold, Benjamin F.; Khush, Ranjiv S.; Ramaswamy, Padmavathi; Rajkumar, Paramasivan; Durairaj, Natesan; Ramaprabha, Prabhakar; Balakrishnan, Kalpana; Colford Jr., John M.

    2015-01-01

    Discreet collection of spot check observations to measure household hygiene conditions is a common measurement technique in epidemiologic studies of hygiene in low-income countries. The objective of this study was to determine whether the collection of spot check observations in longitudinal studies could itself induce reactivity (i.e., change participant behavior). We analyzed data from a 12-month prospective cohort study in rural Tamil Nadu, India that was conducted in the absence of any hygiene or toilet promotion activities. Our data included hygiene and toilet spot checks from 10,427 household visits. We found substantial evidence of participant reactivity to spot check observations of hygiene practices that were easy to modify on short notice. For example, soap observed at the household's primary handwashing location increased from 49% at enrollment to 81% by the fourth visit and remained at or above 77% for the remainder of the study. PMID:25385856

  7. Measuring adolescents' exposure to victimization: The Environmental Risk (E-Risk) Longitudinal Twin Study.

    PubMed

    Fisher, Helen L; Caspi, Avshalom; Moffitt, Terrie E; Wertz, Jasmin; Gray, Rebecca; Newbury, Joanne; Ambler, Antony; Zavos, Helena; Danese, Andrea; Mill, Jonathan; Odgers, Candice L; Pariante, Carmine; Wong, Chloe C Y; Arseneault, Louise

    2015-11-01

    This paper presents multilevel findings on adolescents' victimization exposure from a large longitudinal cohort of twins. Data were obtained from the Environmental Risk (E-Risk) Longitudinal Twin Study, an epidemiological study of 2,232 children (1,116 twin pairs) followed to 18 years of age (with 93% retention). To assess adolescent victimization, we combined best practices in survey research on victimization with optimal approaches to measuring life stress and traumatic experiences, and introduce a reliable system for coding severity of victimization. One in three children experienced at least one type of severe victimization during adolescence (crime victimization, peer/sibling victimization, Internet/mobile phone victimization, sexual victimization, family violence, maltreatment, or neglect), and most types of victimization were more prevalent among children from low socioeconomic backgrounds. Exposure to multiple victimization types was common, as was revictimization; over half of those physically maltreated in childhood were also exposed to severe physical violence in adolescence. Biometric twin analyses revealed that environmental factors had the greatest influence on most types of victimization, while severe physical maltreatment from caregivers during adolescence was predominantly influenced by heritable factors. The findings from this study showcase how distinct levels of victimization measurement can be harmonized in large-scale studies of health and development. PMID:26535933

  8. Measuring adolescents’ exposure to victimization: The Environmental Risk (E-Risk) Longitudinal Twin Study

    PubMed Central

    Fisher, Helen L.; Caspi, Avshalom; Moffitt, Terrie E.; Wertz, Jasmin; Gray, Rebecca; Newbury, Joanne; Ambler, Antony; Zavos, Helena; Danese, Andrea; Mill, Jonathan; Odgers, Candice L.; Pariante, Carmine; Wong, Chloe C.; Arseneault, Louise

    2016-01-01

    This paper presents mutlilevel findings on adolescents’ victimization exposure from a large longitudinal cohort of twins. Data were obtained from the Environmental Risk (E-Risk) Longitudinal Twin Study, an epidemiological study of 2,232 children (1,116 twin pairs) followed to 18 years of age (with 93% retention). To assess adolescent victimization we combined best practices in survey research on victimization with optimal approaches to measuring life stress and traumatic experiences, and introduce a reliable system for coding severe victimization. One in three children experienced at least one type of severe victimization during adolescence (crime victimization, peer/sibling victimization, internet/mobile phone victimization, sexual victimization, family violence, maltreatment, or neglect), and most types of victimization were more prevalent amongst children from low socioeconomic backgrounds. Exposure to multiple victimization types was common, as was re-victimization; over half of those physically maltreated in childhood were also exposed to severe physical violence in adolescence. Biometric twin analyses revealed that environmental factors had the greatest influence on most types of victimization, while severe physical maltreatment from caregivers during adolescence was predominantly influenced by heritable factors. The findings from this study showcase how distinct levels of victimization measurement can be harmonized in large-scale studies of health and development. PMID:26535933

  9. Online Assessment, Measurement and Evaluation: Emerging Practices

    ERIC Educational Resources Information Center

    Williams, David, Ed.; Hricko, Mary, Ed.; Howell, Scott, Ed.

    2006-01-01

    "Online Assessment, Measurement and Evaluation: Emerging Practices" provides a view of the possibilities and challenges facing online educators and evaluators in the 21st Century. As technology evolves and online measurement and assessment follow, "Online Assessment, Measurement and Evaluation: Emerging Practices" uses established evaluation…

  10. On Fitting Nonlinear Latent Curve Models to Multiple Variables Measured Longitudinally

    ERIC Educational Resources Information Center

    Blozis, Shelley A.

    2007-01-01

    This article shows how nonlinear latent curve models may be fitted for simultaneous analysis of multiple variables measured longitudinally using Mx statistical software. Longitudinal studies often involve observation of several variables across time with interest in the associations between change characteristics of different variables measured…

  11. Executive Function in Early Childhood: Longitudinal Measurement Invariance and Developmental Change

    ERIC Educational Resources Information Center

    Willoughby, Michael T.; Wirth, R. J.; Blair, Clancy B.

    2012-01-01

    This study tested the longitudinal measurement invariance and developmental changes of a newly developed battery of executive function (EF) tasks for use in early childhood. The battery was administered in the Family Life Project--a prospective longitudinal study (N = 1,292) of families who were oversampled from low-income and African American…

  12. Vibration Measurement on Reticular Lamina and Basilar Membrane at Multiple Longitudinal Locations

    NASA Astrophysics Data System (ADS)

    Chen, Fangyi; Zha, Dingjun; Choudhury, Niloy; Fridberger, Anders; Nuttall, Alfred L.

    2011-11-01

    The longitudinal distribution of the organ of Corti vibration is important for both understanding the energy delivery and the timing of the cochlear amplification. Recent development on low coherence interferomtry technique allows measuring vibration inside the cochlea. The reticular lamina (RL) vibration spectrum demonstrates that RL vibration leads the basilar membrane (BM). This phase lead is consistent with the idea that the active process may lead the BM vibration. In this study, measurements on multiple longitudinal locations demonstrated similar phase lead. Results on this study suggests that there may be another longitudinal coupling mechanism inside the cochlea other than the traveling wave on BM.

  13. The predictive validity of selection for entry into postgraduate training in general practice: evidence from three longitudinal studies

    PubMed Central

    Patterson, Fiona; Lievens, Filip; Kerrin, Máire; Munro, Neil; Irish, Bill

    2013-01-01

    Background The selection methodology for UK general practice is designed to accommodate several thousand applicants per year and targets six core attributes identified in a multi-method job-analysis study Aim To evaluate the predictive validity of selection methods for entry into postgraduate training, comprising a clinical problem-solving test, a situational judgement test, and a selection centre. Design and setting A three-part longitudinal predictive validity study of selection into training for UK general practice. Method In sample 1, participants were junior doctors applying for training in general practice (n = 6824). In sample 2, participants were GP registrars 1 year into training (n = 196). In sample 3, participants were GP registrars sitting the licensing examination after 3 years, at the end of training (n = 2292). The outcome measures include: assessor ratings of performance in a selection centre comprising job simulation exercises (sample 1); supervisor ratings of trainee job performance 1 year into training (sample 2); and licensing examination results, including an applied knowledge examination and a 12-station clinical skills objective structured clinical examination (OSCE; sample 3). Results Performance ratings at selection predicted subsequent supervisor ratings of job performance 1 year later. Selection results also significantly predicted performance on both the clinical skills OSCE and applied knowledge examination for licensing at the end of training. Conclusion In combination, these longitudinal findings provide good evidence of the predictive validity of the selection methods, and are the first reported for entry into postgraduate training. Results show that the best predictor of work performance and training outcomes is a combination of a clinical problem-solving test, a situational judgement test, and a selection centre. Implications for selection methods for all postgraduate specialties are considered. PMID:24267856

  14. Cultural measures associated with risky sexual behaviors among Latino youth in Southern California: A longitudinal study

    PubMed Central

    Thing, James P.; Baezconde-Garbanati, Lourdes; Schwartz, Seth J.; Soto, Daniel W.; Unger, Jennifer B.

    2014-01-01

    Context Cultural variables have been associated with sexual risk behaviors among Latino youth, but findings across studies are inconsistent. Methods We analyzed data from a longitudinal study of Latino youth in Southern California followed from 2005–2012 to test whether cultural variables measured in high school were associated with sexual risk behaviors in emerging adulthood, and whether gender moderated these associations. We conducted logistic and ordinal regression analyses. Participants were 995 Latino youth. Results The cultural value of respect for parents was negatively associated with an earlier age at sexual debut (odds ratio, 0.8) and not using a condom at most recent sexual intercourse (0.8). U.S. cultural practices (a measure of acculturation) was positively associated with being sexually active (1.2), having concurrent sexual partners (1.5), and among males only, with a higher number of sexual partners (1.3). Second- and third- generation immigrant youth had lower odds of not using a condom at most recent sexual intercourse when compared to first-generation youth (0.6 and 0.5, respectively). Among females, a stronger endorsement of Latino cultural practices was associated with lower odds of more sexual partners (0.8). By contrast, among males, a stronger endorsement of Latino cultural practices was associated with higher odds of more sexual partners (1.4). Conclusions The cultural measures associated with Latino youth’s sexual behaviors differed across outcomes and by gender. Understanding how culture is related to the sexual behaviors of Latino youth may help inform the development of culturally-sensitive sexual health interventions. PMID:24786352

  15. Halitosis: measurement in daily practice.

    PubMed

    Schmidt, Jana; Krause, Felix; Haak, Rainer

    2015-01-01

    Bad breath is a widespread but still largely taboo problem. The dentist is often the first point of contact for affected patients. Initially, the diagnosis and quantification of halitosis provides objective evidence and helps to find the underlying causes, but it is equally important for monitoring the treatment progress. Most often, halitosis is caused intraorally, thus the dentist will also be responsible for initiating an appropriate treatment. Apart from the simple organoleptic examination without the need for additional instruments, several devices for the measurement of halitosis are available which provide a differentiated analysis of the exhaled air by determining and quantifying the detected volatile sulfur compounds. PMID:26046112

  16. Practice based, longitudinal, qualitative interview study of computerised evidence based guidelines in primary care

    PubMed Central

    Rousseau, Nikki; McColl, Elaine; Newton, John; Grimshaw, Jeremy; Eccles, Martin

    2003-01-01

    Objective To understand the factors influencing the adoption of a computerised clinical decision support system for two chronic diseases in general practice. Design Practice based, longitudinal, qualitative interview study. Setting Five general practices in north east England. Participants 13 respondents (two practice managers, three nurses, and eight general practitioners) gave a total of 19 semistructured interviews. 40 people in practices included in the randomised controlled trial (34 doctors, three nurses) and interview study (three doctors, one previously interviewed) gave feedback. Results Negative comments about the decision support system significantly outweighed the positive or neutral comments. Three main areas of concern among clinicians emerged: timing of the guideline trigger, ease of use of the system, and helpfulness of the content. Respondents did not feel that the system fitted well within the general practice context. Experience of “on-demand” information sources, which were generally more positively viewed, informed the comments about the system. Some general practitioners suggested that nurses might find the guideline content more clinically useful and might be more prepared to use a computerised decision support system, but lack of feedback from nurses who had experienced the system limited the ability to assess this. Conclusions Significant barriers exist to the use of complex clinical decision support systems for chronic disease by general practitioners. Key issues include the relevance and accuracy of messages and the flexibility to respond to other factors influencing decision making in primary care. What is already known on this topicRandomised controlled trials of complex computerised decision support systems have found low rates of use and no effects on process and outcomes of careWhat this study addsClinicians found a computerised decision support system for chronic disease in general practice to be difficult to use and unhelpful

  17. A LONGITUDINAL ANALYSIS OF PARENTING PRACTICES, COUPLE SATISFACTION, AND CHILD BEHAVIOR PROBLEMS

    PubMed Central

    Linville, Deanna; Chronister, Krista; Dishion, Tom; Todahl, Jeff; Miller, John; Shaw, Daniel; Gardner, Francis; Wilson, Melvin

    2010-01-01

    This longitudinal study examined the relationship between couple relationship satisfaction, parenting practices, parent depression, and child problem behaviors. The study participants (n = 148) were part of a larger experimental study that examined the effectiveness of a brief family-centered intervention, the Family Check-Up model. Regression analysis results indicated that our proposed model accounted for 38% of the variance in child problem behavior at Time 2, with child problem behavior and couple relationship satisfaction at child age 2 years each accounting for a significant portion of the variance in child problem behavior at age 3. Couple relationship satisfaction directly predicted child behavior problems over time. Clinical and research implications are discussed. PMID:20433599

  18. Application of longitudinal and transversal bioimpedance measurements in peritoneal dialysis at 50 kHz

    NASA Astrophysics Data System (ADS)

    Nescolarde, L.; Doñate, T.; Casañas, R.; Rosell-Ferrer, J.

    2010-04-01

    More relevant information of the fluid changes in peritoneal dialysis (PD) might be obtained with segmental bioimpedance measurements rather than whole-body measurement, who hidden information of body composition. Whole-body and segmental bioimpedance measurements were obtained using 5 configurations (whole-body or right-side (RS), longitudinal-leg (L-LEG), longitudinal-abdomen (L-AB), transversal-abdomen (T-AB), and transversal-leg (T-LEG)) in 20 patients: 15 males (56.5 ± 9.4 yr, 24.2 ± 4.2 kg/m2) and 5 females (58.4 ± 7.1 yr, 28.2 ± 5.9 kg/m2) in peritoneal dialysis (PD). The aim of this study is to analyze the relationship between whole-body, longitudinal-segmental (L-LEG and L-AB) and transversal-segmental (TAB and TLEG) bioimpedance measurement at 50 kHz, with clinical parameters of cardiovascular risk, dyslipidemia, nutrition and hydration. The Kolmogorov-Smirnov test was used for the normality test of all variables. Longitudinal bioimpedance parameters were normalized by the height of the patients. The Spearman correlation was used to analyze the correlation between bioimpedance and clinical parameters. The statistical significance was considered with P < 0.05. Transversal bioimpedance measurements have higher correlation with clinical parameters than longitudinal measurements.

  19. Longitudinal evaluation of patient-reported outcomes measurement information systems measures in pediatric chronic pain.

    PubMed

    Kashikar-Zuck, Susmita; Carle, Adam; Barnett, Kimberly; Goldschneider, Kenneth R; Sherry, David D; Mara, Constance A; Cunningham, Natoshia; Farrell, Jennifer; Tress, Jenna; DeWitt, Esi Morgan

    2016-02-01

    The Patient-Reported Outcomes Measurement Information System (PROMIS) initiative is a comprehensive strategy by the National Institutes of Health to support the development and validation of precise instruments to assess self-reported health domains across healthy and disease-specific populations. Much progress has been made in instrument development, but there remains a gap in the validation of PROMIS measures for pediatric chronic pain. The purpose of this study was to investigate the construct validity and responsiveness to change of 7 PROMIS domains for the assessment of children (ages: 8-18) with chronic pain--Pain Interference, Fatigue, Anxiety, Depression, Mobility, Upper Extremity Function, and Peer Relationships. The PROMIS measures were administered at the initial visit and 2 follow-up visits at an outpatient chronic pain clinic (CPC; N = 82) and at an intensive amplified musculoskeletal pain day-treatment program (N = 63). Aim 1 examined construct validity of PROMIS measures by comparing them with corresponding "legacy" measures administered as part of usual care in the CPC sample. Aim 2 examined sensitivity to change in both CPC and amplified musculoskeletal pain samples. Longitudinal growth models showed that PROMIS' Pain Interference, Anxiety, Depression, Mobility, Upper Extremity, and Peer Relationship measures and legacy instruments generally performed similarly with slightly steeper slopes of improvement in legacy measures. All 7 PROMIS domains showed responsiveness to change. Results offered initial support for the validity of PROMIS measures in pediatric chronic pain. Further validation with larger and more diverse pediatric pain samples and additional legacy measures would broaden the scope of use of PROMIS in clinical research. PMID:26447704

  20. Measurement of the Density Matrix of a Longitudinally Modulated Atomic Beam

    NASA Astrophysics Data System (ADS)

    Rubenstein, Richard A.; Kokorowski, David A.; Dhirani, Al-Amin; Roberts, Tony D.; Gupta, Subhadeep; Lehner, Jana; Smith, Winthrop W.; Smith, Edward T.; Bernstein, Herbert J.; Pritchard, David E.

    1999-09-01

    We present the first measurement of the longitudinal density matrix of a matter-wave beam. Using a unique interferometric scheme, both the amplitude and phase of off-diagonal density matrix elements were determined directly, without the use of traditional tomographic techniques. The measured density matrix of a doubly amplitude modulated atomic sodium beam compares well with theoretical predictions.

  1. Prescribed opioids in primary care: cross-sectional and longitudinal analyses of influence of patient and practice characteristics

    PubMed Central

    Foy, Robbie; Leaman, Ben; McCrorie, Carolyn; Petty, Duncan; House, Allan; Bennett, Michael; Carder, Paul; Faulkner, Simon; Glidewell, Liz; West, Robert

    2016-01-01

    Objectives To examine trends in opioid prescribing in primary care, identify patient and general practice characteristics associated with long-term and stronger opioid prescribing, and identify associations with changes in opioid prescribing. Design Trend, cross-sectional and longitudinal analyses of routinely recorded patient data. Setting 111 primary care practices in Leeds and Bradford, UK. Participants We observed 471 828 patient-years in which all patients represented had at least 1 opioid prescription between April 2005 and March 2012. A cross-sectional analysis included 99 847 patients prescribed opioids between April 2011 and March 2012. A longitudinal analysis included 49 065 patient-years between April 2008 and March 2012. We excluded patients with cancer or treated for substance misuse. Main outcome measures Long-term opioid prescribing (4 or more prescriptions within 12 months), stronger opioid prescribing and stepping up to or down from stronger opioids. Results Opioid prescribing in the adult population almost doubled for weaker opioids over 2005–2012 and rose over sixfold for stronger opioids. There was marked variation among general practices in the odds of patients stepping up to stronger opioids compared with those not stepping up (range 0.31–3.36), unexplained by practice-level variables. Stepping up to stronger opioids was most strongly associated with being underweight (adjusted OR 3.26, 1.49 to 7.17), increasing polypharmacy (4.15, 3.26 to 5.29 for 10 or more repeat prescriptions), increasing numbers of primary care appointments (3.04, 2.48 to 3.73 for over 12 appointments in the year) and referrals to specialist pain services (5.17, 4.37 to 6.12). Compared with women under 50 years, men under 50 were less likely to step down once prescribed stronger opioids (0.53, 0.37 to 0.75). Conclusions While clinicians should be alert to patients at risk of escalated opioid prescribing, much prescribing variation may be attributable to

  2. Measurement of longitudinal emittance growth using a laser-induced neutralization method

    SciTech Connect

    Yuan, V.W.; Garcia, R.; Johnson, K.F.; Saadatmand, K.; Sander, O.R.; Sandoval, D.; Shinas, M.

    1991-01-01

    A laser-induced neutralization technique, LINDA, has been used to study the longitudinal emittance of the 5-MeV H{sup {minus}} beam exiting the drift-tube Linac (DTL) of the Los Alamos Accelerator Test Stand (ATS). By using multiple laser intersection points, longitudinal emittance growths over drift distances of 23.6 and 30.6 cm were measured. Subsequently, a beam transport line, which consisted of one arm of a beam funnel, was substituted for the drift space. Measurements show that the elements of the funnel constrain emittance growth while the H{sup {minus}} beam is contained within these transport elements.

  3. Longitudinal-to-Transverse Mapping for Femtosecond Electron Bunch Length Measurement

    SciTech Connect

    Xiang, Dao; Ding, Yuantao; /SLAC

    2010-08-25

    A longitudinal-to-transverse mapping technique is proposed to measure the length and temporal profile of ultrashort electron bunches. In this scheme a special chicane and a radio-frequency deflecting cavity are used to transform the beam's longitudinal distribution into angular distribution which is further converted to transverse distribution after a parallel-to-point imaging beam line. With this technique, the temporal profile of the electron beam is exactly mapped to the transverse profile. This makes it possible to measure ultrashort electron bunch length with a resolution well beyond 1 femtosecond.

  4. Bayesian regression analysis of data with random effects covariates from nonlinear longitudinal measurements

    PubMed Central

    De la Cruz, Rolando; Meza, Cristian; Arribas-Gil, Ana; Carroll, Raymond J.

    2016-01-01

    Joint models for a wide class of response variables and longitudinal measurements consist on a mixed-effects model to fit longitudinal trajectories whose random effects enter as covariates in a generalized linear model for the primary response. They provide a useful way to assess association between these two kinds of data, which in clinical studies are often collected jointly on a series of individuals and may help understanding, for instance, the mechanisms of recovery of a certain disease or the efficacy of a given therapy. When a nonlinear mixed-effects model is used to fit the longitudinal trajectories, the existing estimation strategies based on likelihood approximations have been shown to exhibit some computational efficiency problems (De la Cruz et al., 2011). In this article we consider a Bayesian estimation procedure for the joint model with a nonlinear mixed-effects model for the longitudinal data and a generalized linear model for the primary response. The proposed prior structure allows for the implementation of an MCMC sampler. Moreover, we consider that the errors in the longitudinal model may be correlated. We apply our method to the analysis of hormone levels measured at the early stages of pregnancy that can be used to predict normal versus abnormal pregnancy outcomes. We also conduct a simulation study to assess the importance of modelling correlated errors and quantify the consequences of model misspecification. PMID:27274601

  5. Measured Effects of a Longitudinal Solenoidal Field on an Iron Quadrupole

    NASA Astrophysics Data System (ADS)

    Ecklund, S.; Seeman, J. T.; Wolf, Z.

    1997-05-01

    We have measured the effects of a longitudinal solenoidal field on the field harmonics of an iron dominated quadrupole. These measurements are useful when designing a colliding beam interaction region where the first quadrupole is very near the solenoidal field of the physics detector. The effects of mirror plates, quadrupole excition, skew quadrupole windings, dipole windings, and solenoidal fields that enter at an angle have been measured. Conclusions and interpretations are given.

  6. Are Measured School Effects Just Sorting? Causality and Correlation in the National Education Longitudinal Survey

    ERIC Educational Resources Information Center

    Levine, David I.; Painter, Gary

    2008-01-01

    Youth who share a school and neighborhood often show similar levels of academic achievement, but some studies find all or most of this correlation is due to sorting (not causation). We analyze the National Education Longitudinal Survey (NELS) in three ways to decompose sorting versus causality: We first control for much richer measures of family…

  7. Longitudinal emittance measurements in the Booster and AGS during the 2014 RHIC gold run

    SciTech Connect

    Zeno, K.

    2014-08-18

    This note describes longitudinal emittance measurements that were made in the Booster and AGS during the 2014 RHIC Gold run. It also contains an overview of the longitudinal aspects of their setup during this run. Each bunch intended for RHIC is composed of beam from 4 Booster cycles, and there are two of them per AGS cycle. For each of the 8 Booster cycles required to produce the 2 bunches in the AGS, a beam pulse from EVIS is injected into the Booster and captured in four h=4 buckets. Then those bunches are accelerated to a porch where they are merged into 2 bunches and then into 1 bunch.

  8. Using growth curve analysis to examine challenges in instrumentation in longitudinal measurement in home visiting.

    PubMed

    Goltz, Heather Honoré; Mena, Kristin Cotter; Swank, Paul R

    2014-01-01

    Home visitation programs aim to decrease child maltreatment, yet limited longitudinal data exists concerning their screening and assessment instruments. "At risk" families (N = 2,054) were screened using the Family Stress Checklist and referred to Healthy Families Indiana. The Home Observation Measurement of the Environment Scale (HOME) and Community Life Skills Scale (CLS) were administered at multiple intervals. Growth curve analyses indicate families with lower HOME and CLS scores received more home visits and visits between assessments. However, these instruments may have "ceiling effects" and may be unsuitable for longitudinal assessment and program evaluation. Programmatic changes were made based on evaluation results. PMID:24405137

  9. Use of Missing Data Methods in Longitudinal Studies: The Persistence of Bad Practices in Developmental Psychology

    ERIC Educational Resources Information Center

    Jelicic, Helena; Phelps, Erin; Lerner, Richard M.

    2009-01-01

    Developmental science rests on describing, explaining, and optimizing intraindividual changes and, hence, empirically requires longitudinal research. Problems of missing data arise in most longitudinal studies, thus creating challenges for interpreting the substance and structure of intraindividual change. Using a sample of reports of longitudinal…

  10. An Overview of Longitudinal Spin Structure Measurements from JLab

    SciTech Connect

    Sulkosky, Vincent A.

    2013-08-01

    Jefferson Lab is currently one of the facilities leading the investigation of the spin structure of the nucleon. Over the past 15 years, several high precision measurements have been completed, extending our knowledge of the polarized structure functions g{sub 1} and g{sub 2} down to Q{sup 2} = 0.02 GeV{sup 2}. In particular, the low-Q{sup 2} range ({<=} 0.1 GeV{sup 2}) from these data allows us to make a benchmark-check of Chiral Perturbation theory ({chi}PT). Previous results for the moments of the spin structure functions in this region have shown mixed agreement. For {Gamma}{sub 1}, the first moment of g{sub 1}, we find good consistency between data and theory. However, we have seen a surprisingly large discrepancy with {chi}PT calculations for the {delta}{sub LT} spin polarizability on the neutron, which is significantly less sensitive to the {Delta}-resonance contribution. These proceedings will discuss the recent experimental effort at low Q{sup 2} from Jefferson Lab, including a discussion of preliminary results on the neutron. The new results on the neutron still show a sizeable discrepancy between data and theory. However, new calculations show improved agreement with data for some observables. In addition, new proton data for g{sub 2} is also expected to help resolve the disagreement for {delta}{sub LT}.

  11. Longitudinal coherence measurements of an extreme-ultraviolet free-electron laser.

    PubMed

    Schlotter, W F; Sorgenfrei, F; Beeck, T; Beye, M; Gieschen, S; Meyer, H; Nagasono, M; Föhlisch, A; Wurth, W

    2010-02-01

    We have measured the average single-pulse longitudinal coherence characteristics of FLASH, a self amplified spontaneous emission free electron laser, at extreme UV wavelengths. Electric field autocorrelation measurements in the time domain were enabled by a wavefront division beam splitter applied to a tunable delay Mach-Zehnder interferometer. These data agree with the spectral bandwidth measurements made in the frequency domain. They exhibit two correlation time scales and the measured coherence curves have relevant implications for single-shot measurements. PMID:20125725

  12. A Quest for Measuring Ion Bunch Longitudinal Profiles with One Picosecond Accuracy in the SNS Linac.

    SciTech Connect

    Aleksandrov, Alexander V; Dickson, Richard W

    2012-01-01

    The SNS linac utilizes several accelerating structures operating at different frequencies and with different transverse focusing structures. Low-loss beam transport requires a careful matching at the transition points in both the transverse and longitudinal axes. Longitudinal beam parameters are measured using four Bunch Shape Monitors (used at many ion accelerator facilities, aka Feschenko devices). These devices, as initially delivered to the SNS, provided an estimated accuracy of about 5 picoseconds, which was sufficient for the initial beam commissioning. New challenges of improving beam transport for higher power operation will require measuring bunch profiles with 1-2 picoseconds accuracy. We have successfully implemented a number of improvements to maximize the performance characteristics of the delivered devices. We will discuss the current status of this instrument, its ultimate theoretical limit of accuracy, and how we measure its accuracy and resolution with real beam conditions.

  13. Knowledge, Attitudes and Practices Related to Visceral Leishmaniasis in Rural Communities of Amhara State: A Longitudinal Study in Northwest Ethiopia

    PubMed Central

    López-Perea, Noemí; Sordo, Luis; Gadisa, Endalamaw; Cruz, Israel; Hailu, Tsegaye; Moreno, Javier; Aseffa, Abraham; Cañavate, Carmen; Custodio, Estefanía

    2014-01-01

    Background In the northwest of Ethiopia, at the South Gondar region, there was a visceral leishmaniasis (VL) outbreak in 2005, making the disease a public health concern for the regional health authorities ever since. The knowledge on how the population perceives the disease is essential in order to propose successful control strategies. Methodology/Principal findings Two surveys on VL knowledge, attitudes and practices were conducted at the beginning (May 2009) and at the end (February 2011) of a VL longitudinal study carried out in rural communities of Libo Kemkem and Fogera, two districts of the Amhara Regional State. Results showed that VL global knowledge was very low in the area, and that it improved substantially in the period studied. Specifically, from 2009 to 2011, the frequency of proper knowledge regarding VL signs and symptoms increased from 47% to 71% (p<0.0001), knowledge of VL causes increased from 8% to 25% (p<0.0001), and knowledge on VL protection measures from 16% to 55% (p<0.0001). Moreover, the improvement observed in VL knowledge was more marked among the families with no previous history of VL case. Finally, in 2011 more than 90% of the households owned at least an impregnated bed net and had been sprayed, and attitudes towards these and other protective measures were very positive (over 94% acceptance for all of them). Conclusions/Significance In 2009 the level of knowledge regarding VL was very low among the rural population of this area, although it improved substantially in the study period, probably due to the contribution of many actors in the area. VL patients and relatives should be appropriately informed and trained as they may act as successful health community agents. VL risk behavioural patterns are subject to change as attitudes towards protective measures were very positive overall. PMID:24743328

  14. Local T2 measurement employing longitudinal Hadamard encoding and adiabatic inversion pulses in porous media.

    PubMed

    Vashaee, S; Newling, B; Balcom, B J

    2015-12-01

    Band selective adiabatic inversion radio frequency pulses were employed for multi-slice T2 distribution measurements in porous media samples. Multi-slice T2 measurement employing longitudinal Hadamard encoding has an inherent sensitivity advantage over slice-by-slice local T2 measurements. The slice selection process is rendered largely immune to B1 variation by employing hyperbolic secant adiabatic inversion pulses, which simultaneously invert spins in several well-defined slices. While Hadamard encoding is well established for local spectroscopy, the current work is the first use of Hadamard encoding for local T2 measurement. PMID:26580063

  15. Local T2 measurement employing longitudinal Hadamard encoding and adiabatic inversion pulses in porous media

    NASA Astrophysics Data System (ADS)

    Vashaee, S.; Newling, B.; Balcom, B. J.

    2015-12-01

    Band selective adiabatic inversion radio frequency pulses were employed for multi-slice T2 distribution measurements in porous media samples. Multi-slice T2 measurement employing longitudinal Hadamard encoding has an inherent sensitivity advantage over slice-by-slice local T2 measurements. The slice selection process is rendered largely immune to B1 variation by employing hyperbolic secant adiabatic inversion pulses, which simultaneously invert spins in several well-defined slices. While Hadamard encoding is well established for local spectroscopy, the current work is the first use of Hadamard encoding for local T2 measurement.

  16. Longitudinal Association between Parenting Practices and Early Sexual Risk Behaviors among Urban African American Adolescents: The Moderating Role of Gender

    ERIC Educational Resources Information Center

    Kapungu, Chisina T.; Holmbeck, Grayson N.; Paikoff, Roberta L.

    2006-01-01

    A sample of 274 African American families, living in impoverished neighborhoods with high HIV rates, participated in a longitudinal study of adolescent sexual development when children were in the 4th or 5th grade. Self-report and observational measures of parental warmth and parental behavioral control were collected from adolescents and parents…

  17. BOOK REVIEW: Practical Density Measurement and Hydrometry

    NASA Astrophysics Data System (ADS)

    Gupta, S. V.

    2003-01-01

    Density determinations are very important not only for science and production but also in everyday life, since very often a product is sold by mass but the content of the package is measured by volume (or vice versa) so that the density is needed to convert the values. In production processes the density serves as a measure of mixing ratios and other properties. In science, the determination of Avogadro's constant using silicon single crystals and the potential replacement of the kilogram prototype boost density determination to an extremely low relative uncertainty of 10-7 or less. The book by S V Gupta explains in detail the foundations of any density measurement, namely the volume determination of solid artefacts in terms of the SI base unit of length and the density of water and mercury. Both the history and the actual state of science are reported. For practical density measurements, these chapters contain very useful formulae and tables. Water is treated in detail since it is most widely used as a standard not only for density determination but also to gravimetrically calibrate the capacity of volumetric glassware. Two thirds of the book are devoted to the practical density measurement of solids and liquids, mainly using classical instruments like pycnometers and hydrometers. Methods using free flotation of samples in a liquid without suspension are especially useful for small samples. Also, density determinations of powders and granular or porous samples are explained. Unfortunately, modern density meters of the oscillation type are dealt with in only a few pages. The book is clearly written and easy to understand. It contains a lot of evaluations of formulae that for practical measurements are represented in detailed tables. Methods and measurement procedures are described in detail, including also the calculation of uncertainty. Listings of the advantages and disadvantages of the different methods are very helpful. S V Gupta has written a book that will be

  18. Drift tube measurements of mobilities and longitudinal diffusion coefficients of ions in gases

    SciTech Connect

    Chelf, R.D.

    1982-01-01

    The zero-field mobilities of Br/sup -/ and NH/sub 4//sup +/ in O/sub 2/ were determined as a function of gas temperature in a high pressure drift tube mass spectrometer. The mobilities and longitudinal diffusion coefficients of the ion-gas combinations Br/sup -/ in Ne and Kr, Li/sup +/ in Xe, and Tl//sup +/ in Kr and Xe were determined as a function of E/N, where E is the electric field strength and N is the gas number density in a low pressure drift tube mass spectrometer. The measured longitudinal diffusion coefficients were used for a test and comparison of the generalized Einstein relations of Viehland-Mason and Waldman-Mason theories. The measured mobilities of Br/sup -/ in Kr and Tl//sup +/ in Kr were used in an iterative-inversion scheme from which the ion-neutral interaction potentials were determined.

  19. Measurement of the beam longitudinal profile in a storage ring bynon-linear laser mixing

    SciTech Connect

    Beche, J.-F.; Byrd, J.; De Santis, S.; Denes, P.; Placidi, M.; Turner, W.; Zolotorev, M.

    2004-05-03

    We report on the development of a new technique for the measurement of the longitudinal beam profile in storage rings. This technique, which has been successfully demonstrated at the Advanced Light Source, mixes the synchrotron radiation with the light from a mode-locked solid state laser oscillator in a non-linear crystal. The up-converted radiation is then detected with a photomultiplier and processed to extract, store, and display the required information. The available choices of laser repetition frequency, pulse width, and phase modulation give a wide range of options for matching the bunch configuration of a particular storage ring. Besides the dynamic measurement of the longitudinal profile of each bunch, the instrument can monitor the evolution of the bunch tails, the presence of untrapped particles and their diffusion into nominally empty RF buckets (''ghostbunches'').

  20. Longitudinal impedance measurement of an RK-TBA induction accelerating gap

    SciTech Connect

    Eylon, S.; Henestroza, E.; Kim, J.-S.; Houck, T.L.; Westenskow, G.A.; Yu, S.S.

    1997-05-01

    Induction accelerating gap designs are being studied for Relativistic Klystron Two-Beam Accelerator (RK-TBA) applications. The accelerating gap has to satisfy the following major requirements: hold-off of the applied accelerating voltage pulse, low transverse impedance to limit beam breakup, low longitudinal impedance at the beam-modulation frequency to minimize power loss. Various gap geometries, materials and novel insulating techniques were explored to optimize the gap design. We report on the experimental effort to evaluate the rf properties of the accelerating gaps in a simple pillbox cavity structure. The experimental cavity setup was designed using the AMOS, MAFIA and URMEL numerical codes. Longitudinal impedance measurements above beam-tube cut-off frequency using a single-wire measuring system are presented.

  1. Microwave measurements of energy lost to longitudinal modes by single electron bunches traversing periodic structures

    SciTech Connect

    Wang, J.W.; Loew, G.A.; Weaver, J.N.; Wilson, P.B.

    1981-10-01

    In the design of future linear colliders, it will be important to minimize the loss of beam energy due to the excitation of higher-order modes in the accelerator structure by single bunches of electrons or positrons. This loss is not only detrimental in itself but also gives rise to energy spectrum widening and transverse emittance growth. Microwave measurements made on disk-loaded and alternating-spoke structures to determine the loss to the longitudinal modes are described. In these measurements the Gaussian bunch is simulated by a current pulse of the same shape transmitted through the structure on an axial center conductor. Results to date are presented for the total longitudinal loss parameter per period K in volts per picocoulomb.

  2. Clinicians’ Perceptions of Implementation Extensiveness of 100% Tobacco Free Practices: A Longitudinal Study of New York State1

    PubMed Central

    de Tormes Eby, Lillian Turner; Laschober, Tanja C.

    2013-01-01

    In 2008, New York State required substance use disorder treatment organizations to be 100% tobacco-free. This longitudinal study examined clinicians’ perceptions of the implementation extensiveness of the tobacco-free practices approximately 10–12 months (Time 1) and 20–24 months (Time 2) post regulation and investigated whether clinicians’ commitment to change and use of provided resources at Time 1 predicts perceptions of implementation extensiveness at Time 2. Clinicians (N = 287) noted a mean implementation of 5.60 patient practices (0–10 scale), 2.33 visitor practices (0–8 scale), and 6.66 employee practices (0–12 scale) at Time 1. At Time 2, clinicians perceived a mean implementation of 5.95 patient practices (no increase from Time 1), 2.89 visitor practices (increase from Time 1), and 7.12 employee practices (no increase from Time 1). Commitment to change and use of resources positively predicted perceived implementation extensiveness of visitor and employee practices. The use of resources positively predicted implementation for patient practices. PMID:23430285

  3. Cognitive performance in relapsing remitting multiple sclerosis: A longitudinal study in daily practice using a brief computerized cognitive battery

    PubMed Central

    2011-01-01

    Background There is need for a cognitive test battery that can be easily used in clinical practice to detect or monitor cognitive performance in patients with multiple sclerosis (MS). In order to conduct, in this patient group, a preliminary investigation of the validity and utility of a brief computerized battery, the Cognitive Drug Research (CDR) battery, we longitudinally assessed cognition in patients with relapsing remitting (RR) MS. Methods Forty-three mildly disabled, clinically active RRMS patients were repeatedly assessed with the Digit Symbol Substitution Test (DSST), Paced Auditory Serial Addition Test (PASAT) and five composite scores derived from the CDR computerized cognitive test system (CDR System): Power of Attention, Continuity of Attention, Quality of Working Memory, Quality of Episodic Memory and Speed of Memory. The Multiple Sclerosis Functional Composite (MSFC) and Expanded Disability Status Scale (EDSS) measured disability. Results The composite scores from the CDR battery generally showed excellent test-retest reliability over the repeated assessments, though was low on occasions for the Quality of Working Memory and Quality of Episodic Memory measures. The CDR measures tended to be highly correlated with other measures of cognition (DSST and PASAT) and were also strongly related to disability (EDSS and MSFC). Baseline scores indicated large impairments to visual information processing speed and attention (DSST, Cohen's d 1.1; Power of Attention d 1.4 [reaction time on tasks of focussed and sustained attention]), and a moderate impairment both to sustained attention (Continuity of Attention d 0.6) and complex information processing speed (Speed of memory d 0.7 [reaction time on tasks of working and episodic Memory]), when compared to normative data derived from healthy volunteers enrolled in a series of separate, prior clinical trials. Working memory (Quality of Working Memory) and episodic memory (Quality of Episodic Memory) were unimpaired

  4. Longitudinal effects of change in body mass on measurements of ventilatory capacity.

    PubMed Central

    Chinn, D. J.; Cotes, J. E.; Reed, J. W.

    1996-01-01

    BACKGROUND: In several longitudinal studies changes in body mass and in forced expiratory volume in one second (FEV1) have been found to be negatively correlated. This paper tests the hypothesis that failure to allow for the association can lead to error in the interpretation of longitudinal measurements of ventilatory capacity. METHODS: Male shipyard workers (n = 1005) were assessed on two occasions with an average interval between measurements of 6.9 years. A respiratory symptoms questionnaire, detailed anthropometric measurements, and dynamic spirometric tests were undertaken. Multiple regression analysis was used to identify variables which contributed to the changes in lung function. RESULTS: After allowing for age and growth in stature, a change in body mass of 1 kg was, on average, associated with a mean (SE) converse change in FEV1 of 17.6 (2.0) ml, and in forced vital capacity (FVC) of 21.1 (2.5) ml. Neglect of changes in body mass (which in this context reflected changes in body fat) led to underestimation of the longitudinal decline in FEV1 with age and failure to detect significant improvements in FEV1, both in smokers following discontinuation of smoking and in shipyard welders and caulker/burners as a consequence of leaving their employment. The estimated peak ages and associated peak levels of the indices were found to differ, depending on whether or not they were expressed at constant body mass. CONCLUSIONS: Neglect of changes in body mass can lead to erroneous conclusions being drawn from longitudinal measurements of FEV1. PMID:8882076

  5. Measurement Practices for Reliability and Power Quality

    SciTech Connect

    Kueck, JD

    2005-05-06

    This report provides a distribution reliability measurement ''toolkit'' that is intended to be an asset to regulators, utilities and power users. The metrics and standards discussed range from simple reliability, to power quality, to the new blend of reliability and power quality analysis that is now developing. This report was sponsored by the Office of Electric Transmission and Distribution, U.S. Department of Energy (DOE). Inconsistencies presently exist in commonly agreed-upon practices for measuring the reliability of the distribution systems. However, efforts are being made by a number of organizations to develop solutions. In addition, there is growing interest in methods or standards for measuring power quality, and in defining power quality levels that are acceptable to various industries or user groups. The problems and solutions vary widely among geographic areas and among large investor-owned utilities, rural cooperatives, and municipal utilities; but there is still a great degree of commonality. Industry organizations such as the National Rural Electric Cooperative Association (NRECA), the Electric Power Research Institute (EPRI), the American Public Power Association (APPA), and the Institute of Electrical and Electronics Engineers (IEEE) have made tremendous strides in preparing self-assessment templates, optimization guides, diagnostic techniques, and better definitions of reliability and power quality measures. In addition, public utility commissions have developed codes and methods for assessing performance that consider local needs. There is considerable overlap among these various organizations, and we see real opportunity and value in sharing these methods, guides, and standards in this report. This report provides a ''toolkit'' containing synopses of noteworthy reliability measurement practices. The toolkit has been developed to address the interests of three groups: electric power users, utilities, and regulators. The report will also serve

  6. Studies of longitudinal profile of electron bunches and impedance measurements at Indus-2 synchrotron radiation source

    NASA Astrophysics Data System (ADS)

    Garg, Akash Deep; Yadav, S.; Kumar, Mukesh; Shrivastava, B. B.; Karnewar, A. K.; Ojha, A.; Puntambekar, T. A.

    2016-04-01

    Indus-2 is a 3rd generation synchrotron radiation source at the Raja Ramanna Centre for Advanced Technology (RRCAT) in India. We study the longitudinal profile of electrons in Indus-2 by using dual sweep synchroscan streak camera at visible diagnostic beamline. In this paper, the longitudinal profiles of electron bunch are analyzed by filling beam current in a single bunch mode. These studies are carried at injection energy (550 MeV) and at ramped beam energy (2.5 GeV). The effects of the wakefield generated interactions between the circulating electrons and the surrounding vacuum chamber are analyzed in terms of measured effects on longitudinal beam distribution. The impedance of the storage ring is obtained by fitting the solutions of Haissinski equation to the measured bunch lengthening with different impedance models. The impedance of storage ring obtained by a series R+L impedance model indicates a resistance (R) of 1350±125 Ω, an inductance (L) of 180±25 nH and broadband impedance of 2.69 Ω. These results are also compared with the values obtained from measured synchronous phase advancing and scaling laws. These studies are very useful in better understanding and control of the electromagnetic interactions.

  7. Discharge rate measurements for Micromegas detectors in the presence of a longitudinal magnetic field

    SciTech Connect

    B. Moreno, S. Aune, J. Ball, G. Charles, A. Giganon, P. Konczykowski, C. Lahonde-Hamdoun, H. Moutarde, S. Procureur, F. Sabatie

    2011-10-01

    We present first discharge rate measurements for Micromegas detectors in the presence of a high longitudinal magnetic field in the GeV kinematical region. Measurements were performed by using two Micromegas detectors and a photon beam impinging a CH{sub 2} target in the Hall B of the Jefferson Laboratory. One detector was equipped with an additional GEM foil, and a reduction of the discharge probability by two orders of magnitude compared to the stand-alone Micromegas was observed. The detectors were p laced in the FROST solenoid providing a longitudinal magnetic field up to 5T. It allowed for precise measurements of the discharge probability dependence with a diffusion-reducing magnetic field. Between 0 and 5T, the discharge probability increased by a factor of 10 for polar angles between 19{degrees} and 34{degrees}. A GEANT4-based simulation developed for sparking rate calculation was calibrated against these data in order to predict the sparking rate in a high longitudinal magnetic field environment. This simulati on is then used to investigate the possible use of Micromegas in the Forward Vertex Tracker (FVT) of the future CLAS12 spectrometer. In the case of the FVT a sparking rate of 1Hz per detector was obtained at the anticipated CLAS12 luminosity.

  8. Experimental study of coupling impedance: Part I longitudinal impedance measurement techniques

    SciTech Connect

    Song, J.J.

    1991-10-22

    Beam coupling impedances for the 7-GeV APS storage ring have been numerically estimated. In order to confirm these calculations, measurements of the coupling impedance of various vacuum components around the main storage ring were done with a coaxial wire method. In this paper, the procedure of the longitudinal impedance measurement techniques will be described. As an example, sections of the Cu beam chamber, the Cu beam + antechambers, and the Al beam + antechambers were used as a device under test (DUT) to obtain the results. The transverse impedance measurements will be described in a separate paper.

  9. Measurements of Direct Photon Double Longitudinal Spin Asymmetry at Large Rapidity

    NASA Astrophysics Data System (ADS)

    Bourgeois, Paul

    2008-10-01

    Direct photon production in polarized p-p collisions is expected to be the cleanest measurement of the gluon polarization. Current measurements using inclusive pion production, in the PHENIX central arms, suggest a small contribution from the gluons to the proton spin in the presently accessible Bjorken x range xBj>10-2. The addition of the Nose Cone Calorimeter (NCC) in the large rapidity 1<η<3 will allow PHENIX to access xBj˜10-3. In this talk I will present the prospects of measuring direct photon double longitudinal spin asymmetry ALL employing the NCC.

  10. Comparison of left ventricular manual versus automated derived longitudinal strain: implications for clinical practice and research.

    PubMed

    Kobayashi, Yukari; Ariyama, Miyuki; Kobayashi, Yuhei; Giraldeau, Genevieve; Fleischman, Dominik; Kozelj, Mirta; Vrtovec, Bojan; Ashley, Euan; Kuznetsova, Tatiana; Schnittger, Ingela; Liang, David; Haddad, Francois

    2016-03-01

    Systolic global longitudinal strain (GLS) is emerging as a useful metric of ventricular function in heart failure and usually assessed using post-processing software. The purpose of this study was to investigate whether longitudinal strain (LS) derived using manual-tracings of ventricular lengths (manual-LS) can be reliable and time efficient when compared to LS obtained by post-processing software (software-LS). Apical 4-chamber view images were retrospectively examined in 50 healthy controls, 100 patients with dilated cardiomyopathy (DCM), and 100 with hypertrophic cardiomyopathy (HCM). We measured endocardial and mid-wall manual-LS and software-LS, using peak of average regional curve [software-LS(a)] and global ventricular lengths [software-LS(l)] according to definition of Lagragian strain. We compared manual-LS and software-LS by using Bland-Altman plot and coefficient of variation (COV). In addition, test-retest was also performed for further assessment of variability in measurements. While manual-LS was obtained in all subjects, software-LS could be obtained in 238 subjects (95 %). The time spent for obtaining manual-LS was significantly shorter than for the software-LS (94 ± 39 s vs. 141 ± 79 s, P < 0.001). Overall, manual-LS had an excellent correlation with both software-LS (a) (R(2) = 0.93, P < 0.001) and software-LS(l) (R(2) = 0.84, P < 0.001). The bias (95 %CI) between endocardial manual-LS and software-LS(a) was 0.4 % [-2.8, 3.6 %] in absolute and 3.5 % [-17.0, 24.0 %] in relative difference while it was 0.4 % [-2.5, 3.3 %] and 3.4 % [-16.2, 23.1 %], respectively with software-LS(l). Mid-wall manual-LS and mid-wall software-LS(a) also had good agreement [a bias (95 % CI) for absolute value of 0.1 % [-2.1, 2.5 %] in HCM, and 0.2 % [-2.2, 2.6 %] in controls]. The COV for manual and software derived LS were below 6 %. Test-retest showed good variability for both methods (COVs were 5.8 and 4.7 for endocardial and mid

  11. Measurement of the longitudinal parameters of an electron beam in a storage ring

    SciTech Connect

    Krinsky, S.

    1989-01-01

    We discuss the determination of the longitudinal parameters of a bunched beam of electrons or positrons circulating in a storage ring. From the analysis of the beam current observed at a fixed azimuthal location, one can learn much about the longitudinal behavior. We present an elementary analysis of the time-dependence of the current. In particular, we discuss the determination of the average current, bunch length, synchrotron oscillation frequency, and the coherent synchrotron oscillation modes associated with longitudinal instabilities. A brief discussion is also given of the incoherent synchrotron oscillations, or Schottky noise. We review the electromagnetic field traveling with a charge in uniform motion, and introduce some of the most common devices used to detect this field: capacitive pick-up, stripline monitor, and DC beam current transformer. Our paper is organized as follows: We discuss the analysis of the time-dependence of the beam current. Then, the measurement of the current is considered. Finally, we describe some measurements of energy spread and bunch lengthening made recently at SLAC on the SLC damping ring. 12 refs., 6 figs.

  12. Measuring Knowledge Integration Learning of Energy Topics: A two-year longitudinal study

    NASA Astrophysics Data System (ADS)

    Liu, Ou Lydia; Ryoo, Kihyun; Linn, Marcia C.; Sato, Elissa; Svihla, Vanessa

    2015-05-01

    Although researchers call for inquiry learning in science, science assessments rarely capture the impact of inquiry instruction. This paper reports on the development and validation of assessments designed to measure middle-school students' progress in gaining integrated understanding of energy while studying an inquiry-oriented curriculum. The assessment development was guided by the knowledge integration framework. Over 2 years of implementation, more than 4,000 students from 4 schools participated in the study, including a cross-sectional and a longitudinal cohort. Results from item response modeling analyses revealed that: (a) the assessments demonstrated satisfactory psychometric properties in terms of reliability and validity; (b) both the cross-sectional and longitudinal cohorts made progress on integrating their understanding energy concepts; and (c) among many factors (e.g. gender, grade, school, and home language) associated with students' science performance, unit implementation was the strongest predictor.

  13. Measurements of fuselage skin strains and displacements near a longitudinal lap joint in a pressurized aircraft

    NASA Technical Reports Server (NTRS)

    Phillips, Edward P.; Britt, Vicki O.

    1991-01-01

    Strains and displacements in a small area near a longitudinal lap joint in the fuselage skin of a B737 aircraft were measured during a pressurization cycle to a differential pressure of 6.2 psi while the aircraft was on the ground. It was found that hoop strains were higher than longitudinal strains at each location; membrane strains in the unreinforced skin were higher than in the joint; membrane strains in the hoop direction, as well as radial displacements, tended to be highest at the mid-bay location between skin reinforcements; significant bending in the hoop direction occurred in the joint and in the skin near the joint, and the bending was unsymmetrically distributed about the stringer at the middle of the joint; and radial displacements were unsymmetrically distributed across the lap joint. The interpretation of the strain gage data for locations on the bonded and riveted lap joint assumed that the joint did not contain disbonded areas.

  14. A Bayesian approach to joint analysis of longitudinal measurements and competing risks failure time data.

    PubMed

    Hu, Wenhua; Li, Gang; Li, Ning

    2009-05-15

    In this paper, we develop a Bayesian method for joint analysis of longitudinal measurements and competing risks failure time data. The model allows one to analyze the longitudinal outcome with nonignorable missing data induced by multiple types of events, to analyze survival data with dependent censoring for the key event, and to draw inferences on multiple endpoints simultaneously. Compared with the likelihood approach, the Bayesian method has several advantages. It is computationally more tractable for high-dimensional random effects. It is also convenient to draw inference. Moreover, it provides a means to incorporate prior information that may help to improve estimation accuracy. An illustration is given using a clinical trial data of scleroderma lung disease. The performance of our method is evaluated by simulation studies. PMID:19308919

  15. Stress Measurements in Shock-Loaded PBX 9501 with Embedded Longitudinal and Lateral Piezoresistive Ytterbium Gauges

    SciTech Connect

    D.E. Hooks

    2004-12-15

    A series of light gas gun impact experiments were performed with piezoresistive ytterbium (Yb) gauges in longitudinal and lateral orientations embedded in the plastic bonded explosive PBX 9501. These experiments were performed to evaluate the feasibility of using this method to measure lateral stresses and shear strength dynamically in PBX 9501. Ytterbium was chosen as a gauge material based on its high piezoresistance changes at low stress levels. Experiments were performed at longitudinal impact stresses of approximately 0.6 GPa, which is above the yield point of Yb, near the dynamic yield point of PBX 9501, at a level that is comparable with other impact data, and relevant to several multidimensional safety tests. Results show that PBX 9501 does maintain strength throughout compression. Because of poor reproducibility observed in the experiments presented, it appears unlikely that stress extraction from these gauge results would yield an estimate of shear strength at this impact stress with acceptable error.

  16. A mixture of hierarchical joint models for longitudinal data with heterogeneity, non-normality, missingness, and covariate measurement error.

    PubMed

    Huang, Yangxin; Yan, Chunning; Yin, Ping; Lu, Meixia

    2016-01-01

    Longitudinal data arise frequently in medical studies and it is a common practice to analyze such complex data with nonlinear mixed-effects (NLME) models. However, the following four issues may be critical in longitudinal data analysis. (i) A homogeneous population assumption for models may be unrealistically obscuring important features of between-subject and within-subject variations; (ii) normality assumption for model errors may not always give robust and reliable results, in particular, if the data exhibit skewness; (iii) the responses may be missing and the missingness may be nonignorable; and (iv) some covariates of interest may often be measured with substantial errors. When carrying out statistical inference in such settings, it is important to account for the effects of these data features; otherwise, erroneous or even misleading results may be produced. Inferential procedures can be complicated dramatically when these four data features arise. In this article, the Bayesian joint modeling approach based on a finite mixture of NLME joint models with skew distributions is developed to study simultaneous impact of these four data features, allowing estimates of both model parameters and class membership probabilities at population and individual levels. A real data example is analyzed to demonstrate the proposed methodologies, and to compare various scenarios-based potential models with different specifications of distributions. PMID:25629642

  17. Linking Perceived Discrimination to Longitudinal Changes in African American Mothers' Parenting Practices

    ERIC Educational Resources Information Center

    Brody, Gene H.; Chen, Yi-Fu; Kogan, Steven M.; Murry, Velma McBride; Logan, Patricia; Luo, Zupei

    2008-01-01

    This longitudinal study was designed to test hypotheses, derived from a stress proliferation framework, regarding the association between perceived racial discrimination and changes in parenting among African American mothers in the rural South. A sample of 139 mothers and their children were interviewed 3 times at 1-year intervals. Mothers…

  18. Basics of Longitudinal Cohort Analysis. Principles and Practices of Student Success

    ERIC Educational Resources Information Center

    Voorhees, Rick; Lee, John

    2009-01-01

    Longitudinal cohort analysis is a powerful tool for helping colleges understand student performance. It involves tracking students as a group or cohort over a specified period of time. The results allow administrators, faculty, and staff to identify groups of students who are succeeding or falling behind and the points in the educational pipeline…

  19. Practical guide for validated memristance measurements

    NASA Astrophysics Data System (ADS)

    Du, Nan; Shuai, Yao; Luo, Wenbo; Mayr, Christian; Schüffny, René; Schmidt, Oliver G.; Schmidt, Heidemarie

    2013-02-01

    Chua [IEEE Trans. Circuit Theory 18, 507-519 (1971), 10.1109/TCT.1971.1083337] predicted rather simple charge-flux curves for active and passive memristors (short for memory resistors) and presented active memristor circuit realizations already in the 1970 s. The first passive memristor has been presented in 2008 [D. B. Strukov, G. S. Snider, and D. R. Williams, Nature (London) 453, 80-83 (2008), 10.1038/nature06932]. Typically, memristors are traced in complicated hysteretic current-voltage curves. Therefore, the true essence of many new memristive devices has not been discovered so far. Here, we give a practical guide on how to use normalized charge-flux curves for the prediction of hysteretic current-voltage characteristics of memristors. In the case of memristive BiFeO3 thin film capacitor structures, the normalized charge-flux curves superimpose for different numbers of measurement points Ns and a different measurement time per measurement point Ts. Such normalized charge-flux curves can be used for the prediction of current-voltage characteristics for input signals with arbitrarily chosen Ns and Ts.

  20. The impact of breathing on HRV measurements: implications for the longitudinal follow-up of athletes.

    PubMed

    Saboul, Damien; Pialoux, Vincent; Hautier, Christophe

    2013-01-01

    The purpose of the present work was to compare daily variations of heart rate variability (HRV) parameters between controlled breathing (CB) and spontaneous breathing (SB) sessions during a longitudinal follow-up of athletes. HRV measurements were performed daily on 10 healthy male runners for 21 consecutive days. The signals were recorded during two successive randomised 5-minutes sessions. One session was performed in CB and the other in SB. The results showed significant differences between the two respiration methods in the temporal, nonlinear and frequency domains. However, significant correlations were observed between CB and SB (higher than 0.70 for RMSSD and SD1), demonstrating that during a longitudinal follow-up, these markers provide the same HRV variations regardless of breathing pattern. By contrast, independent day-to-day variations were observed with HF and LF/HF frequency markers, indicating no significant relationship between SB and CB data over time. Therefore, we consider that SB and CB may be used for HRV longitudinal follow-ups only for temporal and nonlinear markers. Indeed, the same daily increases and decreases were observed whatever the breathing method employed. Conversely, frequency markers did not provide the same variations between SB and CB and we propose that these indicators are not reliable enough to be used for day-to-day HRV monitoring. PMID:24050471

  1. Optical measurement of the longitudinal ion distribution of bunched ion beams in the ESR

    NASA Astrophysics Data System (ADS)

    Wen, W. Q.; Lochmann, M.; Ma, X.; Bussmann, M.; Winters, D. F. A.; Nörtershäuser, W.; Botermann, B.; Geppert, C.; Frömmgen, N.; Hammen, M.; Hannen, V.; Jöhren, R.; Kühl, Th.; Litvinov, Yu. A.; Sánchez, R.; Stöhlker, Th.; Vollbrecht, J.; Weinheimer, C.; Dimopoulou, C.; Nolden, F.; Steck, M.

    2013-05-01

    An optical technique to study the longitudinal distribution of ions in a bunched ion beam circulating in a storage ring is presented. It is based on the arrival-time analysis of photons emitted after collisional excitation of residual gas molecules. The beam-induced fluorescence was investigated in the ultraviolet regime with a channeltron and in the visible region using a photomultiplier tube. Both were applied to investigate the longitudinal shape of bunched and electron-cooled 209Bi80+ ion beams at about 400 MeV/u in the experimental storage ring (ESR) at GSI Helmholtzzentrum für Schwerionenforschung in Darmstadt, Germany. Bunch lengths were determined with an uncertainty of about 0.5 m using the UV-sensitive channeltron and with slightly lower accuracy from the photomultiplier data due to the slower transitions in the red region of the spectrum. The Gaussian shape of the longitudinal distribution of ions inside the bunch was confirmed. With the information of the transverse beam size that can be measured simultaneously by a newly installed ionization profile monitor (IPM) at the ESR, an accurate determination of the ion density in the bunched beam will be allowed.

  2. Measuring flow-mediated dilation through transverse and longitudinal imaging: comparison and validation of methods

    NASA Astrophysics Data System (ADS)

    Stroz, Marianne J.; Fenster, Aaron

    2010-11-01

    Three-dimensional ultrasound images (3DUS), having two spatial and one temporal dimension, were taken of the brachial artery during baseline conditions, in the transverse and longitudinal planes. The transverse images were analyzed by three different techniques used to quantify flow-mediated dilation (FMD): (1) measuring vessel area manually (TIMA), (2) measuring vessel area semi-automatically (TISA) and (3) measuring vessel diameter (TID). The inter- and intra-observer variability and transducer repositioning variability of each method were compared to each other and to the variability of measurements taken using the traditional method of measuring vessel FMD through measuring vessel diameter on longitudinal images (LID). The percent coefficient-of-variation describing the inter-observer variability (COVinter) was similar for the methods, indicating that each method was equally reproducible by the different observers. The percent coefficient-of-variation describing the intra-observer variability (COVintra) and the smallest detectable percent change in diameter (Δdintra) for each method indicated that TID was the most precise at measuring vessel diameter, and could measure the smallest changes in diameter between successive measurements (COVintra = 0.31%, Δdintra = 0.87%). LID performed the poorest (COVintra = 0.57%, Δdintra = 1.59%). The percent coefficient-of-variation describing transducer repositioning (COVrep) and the smallest detectable percent change in FMD over time (ΔFMD) for each method indicated that TIMA was the most reproducible method (COVrep = 2.35%, ΔFMD = 6.52%) closely followed by TISA. TID performed the poorest (COVrep = 5.37%, ΔFMD = 14.89%). TIMA and TISA were found not to be statistically different so we suggest TISA as the method of choice to maximize reproducibility between measurements over time, as it is faster and simpler to perform. In each experiment it was clear that transverse imaging introduced equal or less variability into

  3. Measuring the impact of clinically relevant interprofessional education on undergraduate medical and nursing student competencies: A longitudinal mixed methods approach.

    PubMed

    Brashers, Valentina; Erickson, Jeanne M; Blackhall, Leslie; Owen, John A; Thomas, Shannon M; Conaway, Mark R

    2016-07-01

    Interprofessional education (IPE) to improve collaborative competencies is essential for delivering high-quality care. Yet creating clinically relevant IPE and linking it to improvements in behaviours remains challenging, and few objective measurement instruments are available. We developed a process for creating IPE and objective observational tools through collaborative care best practice models (CCBPMs). These models describe the professional and interprofessional behaviours needed for specific patient populations, illnesses, and care settings. Four IPE workshops based on CCBPMs were implemented for all medical and nursing students during their clinical/clerkships years. Students in Cohort 1 completed two IPE workshops: rapid response and end-of-life. For Cohort 2, students completed four IPE workshops, adding chronic paediatric illness and transitions for the cognitively impaired. Valid and reliable collaborative behaviors observational assessment tools (CBOATs) derived from CCBPMs for the rapid response and end-of-life workshops were developed. CBOATs were used in the longitudinal assessment of student learning for both cohorts during two Interprofessional Teamwork Objective Structured Clinical Examinations (ITOSCEs) conducted before and after the students completed the IPE workshops. Over a 2-year period, 457 students completed the IPE simulations and ITOSCEs. Both medical and nursing students demonstrated significant improvement in CBOAT scores. Comparisons between the cohorts showed that participation in four versus two IPE experiences did not significantly improve most CBOAT scores. We conclude that undergraduate IPE simulation experiences based on CCBPMs result in measurable improvements in learner behaviours necessary for effective collaborative and team-based practice in specific care areas. PMID:27269441

  4. Quantitative muscle strength assessment in duchenne muscular dystrophy: longitudinal study and correlation with functional measures

    PubMed Central

    2012-01-01

    Background The aim of this study was to perform a longitudinal assessment using Quantitative Muscle Testing (QMT) in a cohort of ambulant boys affected by Duchenne muscular dystrophy (DMD) and to correlate the results of QMT with functional measures. This study is to date the most thorough long-term evaluation of QMT in a cohort of DMD patients correlated with other measures, such as the North Star Ambulatory Assessment (NSAA) or thee 6-min walk test (6MWT). Methods This is a single centre, prospective, non-randomised, study assessing QMT using the Kin Com® 125 machine in a study cohort of 28 ambulant DMD boys, aged 5 to 12 years. This cohort was assessed longitudinally over a 12 months period of time with 3 monthly assessments for QMT and with assessment of functional abilities, using the NSAA and the 6MWT at baseline and at 12 months only. QMT was also used in a control group of 13 healthy age-matched boys examined at baseline and at 12 months. Results There was an increase in QMT over 12 months in boys below the age of 7.5 years while in boys above the age of 7.5 years, QMT showed a significant decrease. All the average one-year changes were significantly different than those experienced by healthy controls. We also found a good correlation between quantitative tests and the other measures that was more obvious in the stronger children. Conclusion Our longitudinal data using QMT in a cohort of DMD patients suggest that this could be used as an additional tool to monitor changes, providing additional information on segmental strength. PMID:22974002

  5. A Longitudinal Study of Teaching Practice and Early Career Decisions: A Cautionary Tale

    ERIC Educational Resources Information Center

    Cochran-Smith, Marilyn; McQuillan, Patrick; Mitchell, Kara; Terrell, Dianna Gahlsdorf; Barnatt, Joan; D'Souza, Lisa; Jong, Cindy; Shakman, Karen; Lam, Karen; Gleeson, Ann Marie

    2012-01-01

    Although the turnover rate among beginning teachers has been a major concern for some time, most studies do not link teacher retention with teaching practice. In contrast, this study looks specifically at career decisions coupled with practice. Guided by a view of teaching as social and cultural practice, the study used multiple qualitative data…

  6. Measuring Personality in Wave I of the National Longitudinal Study of Adolescent Health

    PubMed Central

    Young, J. Kenneth; Beaujean, and A. Alexander

    2011-01-01

    The researchers sought to develop a personality measure from items in Wave I of the National Longitudinal Study of Adolescent Health. The study found 13 items from three dimensions of personality (neuroticism, extroversion, and conscientiousness), and then examined the factor structure and internal consistency of each of the three dimensions. Within each personality dimension, the items showed a unidimensional factor structure and internal consistency estimates of the summed similar to scores from NEO Personality Inventories. The results can be used to further examine how child/adolescent personality is related to multiple mental and physical health outcomes in the Add Health database. PMID:21808628

  7. Longitudinal rotating frame relaxation time measurements in infarcted mouse myocardium in vivo.

    PubMed

    Musthafa, Haja-Sherief N; Dragneva, Galina; Lottonen, Line; Merentie, Mari; Petrov, Lyubomir; Heikura, Tommi; Ylä-Herttuala, Elias; Ylä-Herttuala, Seppo; Gröhn, Olli; Liimatainen, Timo

    2013-05-01

    Longitudinal relaxation time in the rotating frame (T1ρ) was measured using continuous wave irradiation in normal and infarcted mouse myocardium in vivo. Significant increase in T1ρ was found after 7 days of infarction when compared with reference myocardium or in myocardium before infarction. Cine MRI and histology were performed to verify the severity of infarction. The time course of T1ρ in the infarct fits better with granulation and scar tissue formation than necrosis and edema. The results of the study show that T1ρ could potentially be a noninvasive quantitative marker for tissue remodeling after ischemic damage. PMID:22736543

  8. Repeatability and Minimal Detectable Change in Longitudinal Median Nerve Excursion Measures During Upper Limb Neurodynamic Techniques in a Mixed Population: A Pilot Study Using Musculoskeletal Ultrasound Imaging.

    PubMed

    Paquette, Philippe; Lamontagne, Martin; Higgins, Johanne; Gagnon, Dany H

    2015-07-01

    This study determined test-retest reliability and minimum detectable change in longitudinal median nerve excursion during upper limb neurodynamic tests (ULNTs). Seven participants with unilateral or bilateral carpal tunnel syndrome and 11 healthy participants were randomly tested with two ULNTs (i.e., tensioner and slider). Each ULNT was performed three times each at 45° and 90° of shoulder abduction on two separate visits. Video sequences of median nerve excursion, recorded by a physical therapist using ultrasound imaging, were quantified using computer software. The generalizability theory, encompassing a G-Study and a D-study, measured the dependability coefficient (Φ) along with standard error of measurement (SEM) accuracy and allowed various testing protocols to be proposed. The highest reliability (Φ = 0.84) and lowest minimal measurement error (SEM = 0.58 mm) of the longitudinal median nerve excursion were reached during the ULNT-slider performed with 45° of shoulder abduction and when measures obtained from three different image sequences recorded during a single visit were averaged. It is recommended that longitudinal median nerve excursion measures computed from three separate image sequences recorded during a single visit be averaged in clinical practice. Ideally, adding a second visit (six image sequences) is also suggested in research protocols. PMID:25868536

  9. Executive Function in Early Childhood: Longitudinal Measurement Invariance and Developmental Change

    PubMed Central

    Willoughby, Michael T.; Wirth, R.J.; Blair, Clancy B.

    2012-01-01

    This study tested the longitudinal measurement invariance and developmental changes of a newly developed battery of executive function (EF) tasks for use in early childhood. The battery was administered in the Family Life Project—a prospective longitudinal study (N = 1292) of families who were over-sampled from low income and African American families at the birth of a new child—at age 3, 4, and 5 year assessments. All six individual EF tasks exhibited strong measurement invariance over time. The EF battery, which was derived from the six individual tasks, exhibited partial strong invariance over time. Second-order latent growth curve models revealed individual differences in the levels but not rates of change in latent EF ability. The functional form of change was nonlinear; 60% of the total change in EF ability that was observed between the 3-5 year assessments occurred between the year 3 and 4 assessments. Results are discussed with respect to the importance of establishing scalable measures of EF ability prior to investigating experiences that predict and/or are predicted by changes in EF during early childhood. PMID:22023561

  10. Longitudinal and transversal bioimpedance measurements in addition to diagnosis of heart failure

    NASA Astrophysics Data System (ADS)

    Ribas, N.; Nescolarde, L.; Domingo, M.; Gastelurrutia, P.; Bayés-Genis, A.; Rosell-Ferrer, J.

    2010-04-01

    Heart Failure (HF) is a clinical syndrome characterised by signs of systemic and pulmonary fluid retention, shortness of breath and/or fatigue. There is a lack of reliable indicators of disease state. Benefits and applicability of non-invasive bioimpedance measurement in the hydration state of soft tissues have been validated, fundamentally, in dialysis patients. Four impedance configurations (2 longitudinal and 2 transversal) were analyzed in 48 HF patients (M=28, F=20) classified according to a clinical disease severity score (CDSS) derived from the Framingham criteria: CDSS<=2 (G1: M = 23, F = 14) and CDSS>2 (G2: M = 5, F = 6). The aim of this study is to analyze longitudinal and transversal bioimpedance measurement at 50 kHz, in addition to clinical diagnosis parameters of heart failure, including: clinical disease severity score (CDSS) and a biomarker concentrations (NT-proBNP). The Kolmogorov-Smirnov test was used for the normality test of all variables. The CDSS, NTproBNP and impedance parameters between groups (G1 and G2) were compared by mean of Mann Withney U-test. The statistical significance was considered with P < 0.05. Whole-body impedance measured was analyzed using RXc graph.

  11. Does counterterrorist legislation hurt human rights practices? A longitudinal cross-national analysis.

    PubMed

    Shor, Eran; Filkobski, Ina; Ben-Nun Bloom, Pazit; Alkilabi, Hayder; Su, William

    2016-07-01

    In the aftermath of the 9/11 terrorist attacks, many countries have passed new counterterrorist legislation. One of the common assumptions about such legislation is that it comes with a price: a compromise to practices of human rights. Previous research, looking at a wide range of case studies, suggested that this is indeed the case and that counterterrorist legislation often leads to subsequent repression. However, no large-scale cross-national study has yet assessed this relationship. Relying on a newly assembled database on nation-level counterterrorist legislation for the years 1981-2009, we conduct a cross-national time series analysis of legislation and repression. Our analyses find little evidence for a significant relationships between national counterterrorist legislation and various measures of core human rights in most countries. However, while legislation does not affect repression of physical integrity rights in countries with low and high levels of repression, it is associated with greater state repression in countries with intermediate scores of repression. PMID:27194654

  12. Longitudinal leak point pressure measurements in rats using a modified port à cath system.

    PubMed

    van Asselt, Els; van Mastrigt, Ron

    2013-12-01

    Stress urinary incontinence, defined as involuntary loss of urine secondary to an increase in abdominal pressure, represents one of the most significant urological problems. Several animal models to simulate stress urinary incontinence have been presented, including methods to quantify leak point pressure. We have modified an existing leak point pressure procedure to longitudinally quantify stress urinary incontinence in rats by introducing the port à cath system. Reproducible leak point pressure measurements were carried out over a period of more than 40 days at different bladder volumes. Leak point pressure neither showed a significant relationship with the number of times anesthesia was applied nor a significant change over time. The port à cath system provided a reliable, sensitive device for longitudinal urinary bladder pressure measurements in animals with an implanted bladder catheter. This set-up therefore enables the evaluation of bladder pressure in different models for stress urinary incontinence, such as vaginal distention or pudendal transection over long periods of time within the same animal. PMID:23587018

  13. Longitudinal force measurement in continuous welded rail with bi-directional FBG strain sensors

    NASA Astrophysics Data System (ADS)

    Wang, Ping; Xie, Kaize; Shao, Liyang; Yan, Lianshan; Xu, Jingmang; Chen, Rong

    2016-01-01

    In this work, a new method has been proposed to accurately determine longitudinal force measurement in continuous welded rail (CWR) with bi-directional fiber Bragg grating (B-FBGs) strain sensors (vertically and longitudinally installed according to the axis of rail). The response of B-FBGs has been theoretically analyzed by binding on CWR under different restrained conditions, where the coefficient of strain sensitivity of FBG is calibrated by its temperature sensitivity. Then the proposed sensor structure has been installed at two elaborately selected points on the subgrade on a Chinese high-speed railway in field. The experiment lasts for about 23 h. During the experiment, the rail temperature varied by about 7.8 °C and the differentials of relative value of wavelength change of B-FBGs of two points were 1.7850 × 10-5 and 1.4969 × 10-5. The maximum difference between the experimental and theoretical results is 13.8 kN. The experimental results agree with the theoretical analysis very well. To guarantee the measurement accuracy of over 95%, the ratio of strain sensitivity coefficients of two FBG sensors of B-FBGs structure at one test point shall be within 0.78 ˜ 1.22.

  14. 38 CFR 21.7674 - Measurement of practical training courses.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    .... (1) Courses for the objective of registered nurse or registered professional nurse will be measured...) Courses offered by institutions of higher learning which lead to the objective of practical nurse, practical trained nurse, or licensed practical nurse will be measured on credit hours or clock hours...

  15. Longitudinal assessment of trait emotional intelligence: measurement invariance and construct continuity from late childhood to adolescence.

    PubMed

    Keefer, Kateryna V; Holden, Ronald R; Parker, James D A

    2013-12-01

    Amid the growing efforts to promote positive youth development, trait emotional intelligence (TEI) has emerged as an important protective factor in the processes of resilience and adaptation. The inclusion of a brief form of the Emotional Quotient Inventory-Youth Version (EQi:YV-Brief) in the Canadian National Longitudinal Survey of Children and Youth (NLSCY) presents a unique opportunity to study the developmental dynamics of TEI during the transition from childhood to adolescence. However, before drawing any inferences about construct continuity and change, researchers must establish that the EQi:YV-Brief functions equivalently over time. This study tested configural, metric, scalar, and residual measurement invariance of the EQi:YV-Brief over a 6-year period from late childhood (age 10-11) to adolescence (age 16-17). Longitudinal mean and covariance structures models were fitted to the data from 773 NLSCY participants (51% girls) who completed the EQi:YV-Brief at 4 biennial cycles. Three of the 4 EQi:YV-Brief subscales were found to be fully invariant at ages 12-13 through 17-18 and partially invariant at age 10-11. Controlling for partial noninvariance, we also investigated patterns of rank-order stability and mean-level change in TEI. These exploratory analyses showed that individual differences in TEI became increasingly more stable with age and that changes in mean TEI levels followed a complex nonlinear pattern over time. The results supported the longitudinal utility of 3 of the 4 EQi:YV-Brief subscales used in the NLSCY, supporting their further use in research on the developmental dynamics of TEI. PMID:23914954

  16. Integrative Data Analysis through Coordination of Measurement and Analysis Protocol across Independent Longitudinal Studies

    ERIC Educational Resources Information Center

    Hofer, Scott M.; Piccinin, Andrea M.

    2009-01-01

    Replication of research findings across independent longitudinal studies is essential for a cumulative and innovative developmental science. Meta-analysis of longitudinal studies is often limited by the amount of published information on particular research questions, the complexity of longitudinal designs and the sophistication of analyses, and…

  17. Measurement of the Longitudinal Dynamic Modulus in Macroscopically Ordered Triblock Copolymers using Brillouin Light Scattering

    NASA Astrophysics Data System (ADS)

    Lehman, S. Y.; McNeil, L. E.; Albalak, Ramon; Grimsditch, M.

    1996-11-01

    Triblock copolymers, under certain preparation conditions, organize themselves into macroscopically-ordered, though microscopically-disordered films. We studied films of styrene-butadiene-styrene of varying molecular weight ratios, organized either in lamellae or in cylinders of styrene hexagonally packed in a matrix of butadiene. The polymer chains are tethered at the styrene-butadiene interface, constraining their motion. These films have possible applications including optical waveguides and quantum wire arrays. We have studied the longitudinal acoustic modes in the temperature range 20-475 K in the hypersonic frequency regime using Brillouin light scattering. In addition to measuring the storage modulus M' from the Brillouin frequency shift, we also obtain the loss modulus M" by measuring the FWHM of the Brillouin peaks. Using M" to determine the relaxation times of the polymer strands, we then study the effects of chain tethering on the polymer chain dynamics.

  18. Reliability of neuroanatomical measurements in a multisite longitudinal study of youth at risk for psychosis.

    PubMed

    Cannon, Tyrone D; Sun, Frank; McEwen, Sarah Jacobson; Papademetris, Xenophon; He, George; van Erp, Theo G M; Jacobson, Aron; Bearden, Carrie E; Walker, Elaine; Hu, Xiaoping; Zhou, Lei; Seidman, Larry J; Thermenos, Heidi W; Cornblatt, Barbara; Olvet, Doreen M; Perkins, Diana; Belger, Aysenil; Cadenhead, Kristin; Tsuang, Ming; Mirzakhanian, Heline; Addington, Jean; Frayne, Richard; Woods, Scott W; McGlashan, Thomas H; Constable, R Todd; Qiu, Maolin; Mathalon, Daniel H; Thompson, Paul; Toga, Arthur W

    2014-05-01

    Multisite longitudinal neuroimaging designs are used to identify differential brain structural change associated with onset or progression of disease. The reliability of neuroanatomical measurements over time and across sites is a crucial aspect of power in such studies. Prior work has found that while within-site reliabilities of neuroanatomical measurements are excellent, between-site reliability is generally more modest. Factors that may increase between-site reliability include standardization of scanner platform and sequence parameters and correction for between-scanner variations in gradient nonlinearities. Factors that may improve both between- and within-site reliability include use of registration algorithms that account for individual differences in cortical patterning and shape. In this study 8 healthy volunteers were scanned twice on successive days at 8 sites participating in the North American Prodrome Longitudinal Study (NAPLS). All sites employed 3 Tesla scanners and standardized acquisition parameters. Site accounted for 2 to 30% of the total variance in neuroanatomical measurements. However, site-related variations were trivial (<1%) among sites using the same scanner model and 12-channel coil or when correcting for between-scanner differences in gradient nonlinearity and scaling. Adjusting for individual differences in sulcal-gyral geometries yielded measurements with greater reliabilities than those obtained using an automated approach. Neuroimaging can be performed across multiple sites at the same level of reliability as at a single site, achieving within- and between-site reliabilities of 0.95 or greater for gray matter density in the majority of voxels in the prefrontal and temporal cortical surfaces as well as for the volumes of most subcortical structures. PMID:23982962

  19. Anthropometric Measurements and Dental Caries in Children: A Systematic Review of Longitudinal Studies123

    PubMed Central

    Li, Ling-Wei; Wong, Hai Ming; Peng, Si-Min; McGrath, Colman P

    2015-01-01

    There is growing interest in the association between anthropometric measurements and dental caries in childhood over time (life-course studies). The aim of this review was to identify and systematically review the evidence of the association between anthropometric measurements and dental caries in childhood over time. PubMed, Institute for Scientific Information (ISI) Web of Knowledge, the Cochrane Library, and 6 other databases were searched to identify effective articles. A systematic approach involving critical appraisal was conducted to examine the relation between anthropometric measurements and dental caries in preschool- and school-aged populations from longitudinal studies. An initial search identified 1338 studies, with 59 potentially effective studies (κ = 0.82) and 17 effective studies (κ = 0.88). The quality of reporting among the studies ranged from 19.5 to 30.0 according to the Strengthening the Reporting of Observational studies in Epidemiology (STROBE) criteria. Among the effective studies, 2 studies in which caries was used to predict anthropometric measurements consistently found an inverse association and 15 studies in which anthropometric measurements were used to predict caries were inconsistent, with results appearing to be influenced by nonuniformity of assessments, setting, and procedure of measurements; age and ethnicity of participants; and confounders of dental caries. In conclusion, among >1000 studies identified, 17 informed this systematic review. The quality of reporting of these studies varied considerably. Evidence of the association between anthropometric measurements and dental caries is conflicting and remains inconclusive. PMID:25593143

  20. Understanding and measuring parent use of food to soothe infant and toddler distress: A longitudinal study from 6 to 18 months of age.

    PubMed

    Stifter, Cynthia A; Moding, Kameron J

    2015-12-01

    The present study examined the development of parent use of food to soothe infant distress by examining this feeding practice longitudinally when infants were 6, 12 and 18 months of age. Two measures of feeding to soothe were obtained: parent self-report and observations of food to soothe during each laboratory visit. Demographic and maternal predictors of food to soothe were examined as well as the outcome, infant weight gain. The findings showed that the two measures of food to soothe were unrelated but did reveal similar and unique relations with predictor variables such as parent feeding style and maternal self-efficacy. Only observations of the use of food to soothe were related to infant weight gain. The findings indicate that the two measures of food to soothe may be complementary and that observations of this feeding practice may capture certain relations that are not obtained through the use of self-report. PMID:26164121

  1. Longitudinal MR cortical thinning of individuals and its correlation with PET metabolic reduction: a measurement consistency and correctness studies

    NASA Astrophysics Data System (ADS)

    Lin, Zhongmin S.; Avinash, Gopal; McMillan, Kathryn; Yan, Litao; Minoshima, Satoshi

    2014-03-01

    Cortical thinning and metabolic reduction can be possible imaging biomarkers for Alzheimer's disease (AD) diagnosis and monitoring. Many techniques have been developed for the cortical measurement and widely used for the clinical statistical studies. However, the measurement consistency of individuals, an essential requirement for a clinically useful technique, requires proper further investigation. Here we leverage our previously developed BSIM technique 1 to measure cortical thickness and thinning and use it with longitudinal MRI from ADNI to investigate measurement consistency and spatial resolution. 10 normal, 10 MCI, and 10 AD subjects in their 70s were selected for the study. Consistent cortical thinning patterns were observed in all baseline and follow up images. Rapid cortical thinning was shown in some MCI and AD cases. To evaluate the correctness of the cortical measurement, we compared longitudinal cortical thinning with clinical diagnosis and longitudinal PET metabolic reduction measured using 3D-SSP technique2 for the same person. Longitudinal MR cortical thinning and corresponding PET metabolic reduction showed high level pattern similarity revealing certain correlations worthy of further studies. Severe cortical thinning that might link to disease conversion from MCI to AD was observed in two cases. In summary, our results suggest that consistent cortical measurements using our technique may provide means for clinical diagnosis and monitoring at individual patient's level and MR cortical thinning measurement can complement PET metabolic reduction measurement.

  2. A Longitudinal Analysis of Adolescent Smoking: Using Smoking Status to Differentiate the Influence of Body Weight Measures

    ERIC Educational Resources Information Center

    Hong, Traci; Johnson, Carolyn

    2013-01-01

    Background: Previous research has reported mixed results on the association between body weight measures (ie, perception of weight and weight loss goal) and cigarette smoking prevalence--and how these associations vary by sex and race. This longitudinal study assessed the relationship between these 2 body weight measures and smoking prevalence by…

  3. Modeling Life-Span Growth Curves of Cognition Using Longitudinal Data with Multiple Samples and Changing Scales of Measurement

    ERIC Educational Resources Information Center

    McArdle, John J.; Grimm, Kevin J.; Hamagami, Fumiaki; Bowles, Ryan P.; Meredith, William

    2009-01-01

    The authors use multiple-sample longitudinal data from different test batteries to examine propositions about changes in constructs over the life span. The data come from 3 classic studies on intellectual abilities in which, in combination, 441 persons were repeatedly measured as many as 16 times over 70 years. They measured cognitive constructs…

  4. The Role of Environment in the Development of Reading Skills: A Longitudinal Study of Preschool and School-Age Measures.

    ERIC Educational Resources Information Center

    Molfese, Victoria J.; Modglin, Arlene; Molfese, Dennis L.

    2003-01-01

    A longitudinal study of 113 children (ages 3-10), including 35 with poor reading skills, found both socioeconomic status, Home Observation for Measurement of the Environment scores, and reading achievement scores were related to reading abilities, but preschool environment measures were more strongly and consistently related to and predictive of…

  5. Internalizing and Externalizing Behavior Problem Scores: Cross-Ethnic and Longitudinal Measurement Invariance of the Behavior Problem Index

    ERIC Educational Resources Information Center

    Guttmannova, Katarina; Szanyi, Jason M.; Cali, Philip W.

    2008-01-01

    Accurate measurement of behavioral functioning is a cornerstone of research on disparities in child development. This study used the National Longitudinal Survey of Youth 1979 (NLSY79) data to test measurement invariance of the Behavior Problem Index (BPI) during middle childhood across three ethnic groups. Using the internalizing and…

  6. Causal Inference in Longitudinal Comparative Effectiveness Studies With Repeated Measures of A Continuous Intermediate Variable

    PubMed Central

    Wang, Chen-Pin; Jo, Booil; Brown, C. Hendricks

    2014-01-01

    We propose a principal stratification approach to assess causal effects in non-randomized longitudinal comparative effectiveness studies with a binary endpoint outcome and repeated measures of a continuous intermediate variable. Our method is an extension of the principal stratification approach by Lin et al. [10,11], originally proposed for a longitudinal randomized study to assess the treatment effect of a continuous outcome adjusting for the heterogeneity of a repeatedly measured binary intermediate variable. Our motivation for this work comes from a comparison of the effect of two glucose-lowering medications on a clinical cohort of patients with type 2 diabetes. Here we consider a causal inference problem assessing how well the two medications work relative to one another on two binary endpoint outcomes: cardiovascular disease related hospitalization and all-cause mortality. Clinically, these glucose-lowering medications can have differential effects on the intermediate outcome, glucose level over time. Ultimately we want to compare medication effects on the endpoint outcomes among individuals in the same glucose trajectory stratum while accounting for the heterogeneity in baseline covariates (i.e., to obtain “principal effects” on the endpoint outcomes). The proposed method involves a 3-step model estimation procedure. Step 1 identifies principal strata associated with the intermediate variable using hybrid growth mixture modeling analyses [13]. Step 2 obtains the stratum membership using the pseudoclass technique [17,18], and derives propensity scores for treatment assignment. Step 3 obtains the stratum-specific treatment effect on the endpoint outcome weighted by inverse propensity probabilities derived from Step 2. PMID:24577715

  7. Causal inference in longitudinal comparative effectiveness studies with repeated measures of a continuous intermediate variable.

    PubMed

    Wang, Chen-Pin; Jo, Booil; Brown, C Hendricks

    2014-09-10

    We propose a principal stratification approach to assess causal effects in nonrandomized longitudinal comparative effectiveness studies with a binary endpoint outcome and repeated measures of a continuous intermediate variable. Our method is an extension of the principal stratification approach originally proposed for the longitudinal randomized study "Prevention of Suicide in Primary Care Elderly: Collaborative Trial" to assess the treatment effect on the continuous Hamilton depression score adjusting for the heterogeneity of repeatedly measured binary compliance status. Our motivation for this work comes from a comparison of the effect of two glucose-lowering medications on a clinical cohort of patients with type 2 diabetes. Here, we consider a causal inference problem assessing how well the two medications work relative to one another on two binary endpoint outcomes: cardiovascular disease-related hospitalization and all-cause mortality. Clinically, these glucose-lowering medications can have differential effects on the intermediate outcome, glucose level over time. Ultimately, we want to compare medication effects on the endpoint outcomes among individuals in the same glucose trajectory stratum while accounting for the heterogeneity in baseline covariates (i.e., to obtain 'principal effects' on the endpoint outcomes). The proposed method involves a three-step model estimation procedure. Step 1 identifies principal strata associated with the intermediate variable using hybrid growth mixture modeling analyses. Step 2 obtains the stratum membership using the pseudoclass technique and derives propensity scores for treatment assignment. Step 3 obtains the stratum-specific treatment effect on the endpoint outcome weighted by inverse propensity probabilities derived from Step 2. PMID:24577715

  8. "Collaborative-ready" students: Exploring factors that influence collaboration during a longitudinal interprofessional education practice experience.

    PubMed

    Rotz, Melissa E; Dueñas, Gladys G

    2016-03-01

    A goal of interprofessional education (IPE) is to prepare "collaborative-ready" healthcare professionals to ultimately improve health outcomes. The objective of our study was to explore student-reported factors that influence collaboration within our longitudinal IPE experience. Twenty-five first-year pharmacy students and 50 first-year medical students enrolled in IPE courses were invited to participate in three focus groups. Focus group responses were audio-recorded, transcribed verbatim, and applied to a qualitative thematic analysis. Eighteen students participated with six students in each group. Compared to the medical students, the pharmacy students were younger (22 vs. 26 years), had earned only a high school diploma, and had less healthcare experience. Emergent themes that students reported revealed various factors that can facilitate and inhibit collaboration among student participants. These findings can inform curricular redesign to focus on: clarifying provider roles, requiring ongoing preceptor development, enhancing course orientation, and coordinating student schedules to better prepare "collaborative-ready" students. PMID:26889775

  9. The Impact of Residency Training on Physicians' AIDS-Related Treatment Practices: A Longitudinal Panel Study.

    ERIC Educational Resources Information Center

    Yedidia, Michael J.; Berry, Carolyn A.

    1999-01-01

    Study of 394 physicians graduating in 1989 from six New York medical schools found that certain residency-training factors had sustained effects on physician behavior in caring for AIDS (acquired immune deficiency syndrome) patients, but not on the number of patients treated. Determinants of treatment practice included residency environment,…

  10. Secondary School Science Curricula Practices: A Ten-Year Longitudinal Study of Schools in Ten States.

    ERIC Educational Resources Information Center

    Mahmoud, Hussein Bashir

    This study was designed to identify: (1) status of science teaching and science teachers' and principals' attitudes toward change in science curricula and school practices during the 1979/80 school year in 100 public secondary schools (grades 7-12) that participated in a previous study in 1970/71, and (2) changes that have occurred in science…

  11. Low-Income Mothers' Food Practices with Young Children: A Qualitative Longitudinal Study

    ERIC Educational Resources Information Center

    Harden, Jeni; Dickson, Adele

    2015-01-01

    Objective: Young children living in socioeconomically deprived areas of Scotland have an increased risk of becoming overweight or obese. To enhance understanding of the wider contexts within which family food practices are developed, this study examined the experiences of low-income mothers with young children. Design: Qualitative longitudinal…

  12. Parental feeding practices and child weight status in Mexican American families: A longitudinal analysis

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Parental feeding practices are thought to influence children's weight status, through children's eating behavior and nutritional intake. However, because most studies have been cross-sectional, the direction of influence is unclear. Moreover, although obesity rates are high among Latino children, fe...

  13. Longitudinal occupancy of controlled access right-of-way by utilities. A synthesis of highway practice

    SciTech Connect

    Williams, R.L.

    1996-06-01

    This synthesis will be of interest to transportation agency administrators, design engineers, maintenance engineers and maintenance staff, traffic engineers, and safety officials. It will also provide useful information to the utilities and telecommunications industries. Information is presented on the state transportation agencies` policies, practices, and experience associated with occupancy of the rights-of-way on controlled- (or Limited-) access highways.

  14. The 9-item Bergen Burnout Inventory: factorial validity across organizations and measurements of longitudinal data.

    PubMed

    Feldt, Taru; Rantanen, Johanna; Hyvönen, Katriina; Mäkikangas, Anne; Huhtala, Mari; Pihlajasaari, Pia; Kinnunen, Ulla

    2014-01-01

    The present study tested the factorial validity of the 9-item Bergen Burnout Inventory (BBI-9). The BBI-9 is comprised of three core dimensions: (1) exhaustion at work; (2) cynicism toward the meaning of work; and (3) sense of inadequacy at work. The study further investigated whether the three-factor structure of the BBI-9 remains the same across different organizations (group invariance) and measurement time points (time invariance). The factorial group invariance was tested using a cross-sectional design with data pertaining to managers (n=742), and employees working in a bank (n=162), an engineering office (n=236), a public sector organization divided into three service areas: administration (n=102), education and culture (n=581), and social affairs and health (n=1,505). Factorial time invariance was tested using longitudinal data pertaining to managers, with three measurements over a four-year follow-up period. The confirmatory factor analysis revealed that the three-factor structure of the BBI-9 was invariant across cross-sectional samples. The factorial invariance was also supported across measurement times. To conclude, the factorial structure of the BBI-9 was found to remain the same regardless of the sample properties and measurement times. PMID:24366535

  15. Longitudinal association between toenail selenium levels and measures of subclinical atherosclerosis: the CARDIA trace element study

    PubMed Central

    Xun, Pengcheng; Liu, Kiang; Morris, J Steven; Daviglus, Martha L; He, Ka

    2010-01-01

    Objectives To examine the longitudinal association between toenail selenium levels and sub-clinical atherosclerosis over an 18-year period. Methods Toenail selenium concentrations were examined among 3112 Americans age 20–32 years in 1987 and measured by instrumental neutron-activation analysis. Subclinical atherosclerosis, including common, bulb and internal carotid intima-media thickness (CIMT), was measured in 2005 and coronary artery calcium (CAC) score in 2000 and 2005. General linear regression was developed examining the relation between toenail selenium levels and CIMTs, and logistic regression for repeated outcomes was employed estimating the risk of having CAC>0. Results After adjustment for potential confounders, no associations were observed between toenail selenium levels and CIMTs as well as CAC score. Comparing participants in the highest with the lowest quintile of selenium, the CIMT was 0.005mm (SE=0.008mm, Ptrend=0.39), 0.018mm (SE=0.019mm, Ptrend=0.49), and 0.017mm (SE=0.014mm, Ptrend=0.21) thicker measured in common, bulb and internal carotid, respectively. The adjusted odds ratio of having CAC>0 was 0.95 (95%CI: 0.67–1.35; Ptrend=0.999). Conclusions No associations were observed between toenail selenium and measures of subclinical atherosclerosis among American young adults. This study does not support an atherosclerotic mechanism of selenium for risk reduction of cardiovascular disease. PMID:20138620

  16. Factor Structure and Longitudinal Measurement Invariance of the Demand Control Support Model: An Evidence from the Swedish Longitudinal Occupational Survey of Health (SLOSH)

    PubMed Central

    Chungkham, Holendro Singh; Ingre, Michael; Karasek, Robert; Westerlund, Hugo; Theorell, Töres

    2013-01-01

    Objectives To examine the factor structure and to evaluate the longitudinal measurement invariance of the demand-control-support questionnaire (DCSQ), using the Swedish Longitudinal Occupational Survey of Health (SLOSH). Methods A confirmatory factor analysis (CFA) and multi-group confirmatory factor analysis (MGCFA) models within the framework of structural equation modeling (SEM) have been used to examine the factor structure and invariance across time. Results Four factors: psychological demand, skill discretion, decision authority and social support, were confirmed by CFA at baseline, with the best fit obtained by removing the item repetitive work of skill discretion. A measurement error correlation (0.42) between work fast and work intensively for psychological demands was also detected. Acceptable composite reliability measures were obtained except for skill discretion (0.68). The invariance of the same factor structure was established, but caution in comparing mean levels of factors over time is warranted as lack of intercept invariance was evident. However, partial intercept invariance was established for work intensively. Conclusion Our findings indicate that skill discretion and decision authority represent two distinct constructs in the retained model. However removing the item repetitive work along with either work fast or work intensively would improve model fit. Care should also be taken while making comparisons in the constructs across time. Further research should investigate invariance across occupations or socio-economic classes. PMID:23950957

  17. Longitudinal emittance: An introduction to the concept and survey of measurement techniques including design of a wall current monitor

    SciTech Connect

    Webber, R.C.

    1990-03-01

    The properties of charged particle beams associated with the distribution of the particles in energy and in time can be grouped together under the category of longitudinal emittance. This article is intended to provide an intuitive introduction to the concepts longitudinal emittance; to provide an incomplete survey of methods used to measure this emittance and the related properties of bunch length and momentum spread; and to describe the detailed design of a 6 Ghz bandwidth resistive wall current monitor useful for measuring bunch shapes of moderate to high intensity beams. Overall, the article is intended to be broad in scope, in most cases deferring details to cited original papers. 37 refs., 21 figs.

  18. Measurement of Single and Double Spin Asymmetries in Deep Inelastic Pion Electroproduction with a Longitudinally Polarized Target

    SciTech Connect

    Avakian, H; Bosted, P; Elouadrhiri, L; Adhikari, K P; Aghasyan, M; Amaryan, M; Anghinolfi, M; Baghdasaryan, H; Ball, J; Battaglieri, M; Bedlinskiy, I; Biselli, A S; Branford, D; Briscoe, W J; Brooks, W; Carman, D S; Casey, L; Cole, P L; Collins, P; Crabb, D; Crede, V; D'Angelo, A; Daniel, A; Dashyan, N; DeVita, R; DeSanctis, E; Deur, A; Dey, B; Dhamija, S; Dickson, R; Djalali, C; Dodge, G; Doughty, D; Dupre, R; El Alaoui, A; Eugenio, P; Fegan, S; Fersch, M; Guler, N; Guo, L; Hafidi, K; Hakobyan, H; Hanretty, C; Hassall, N; Heddle, D; Hicks, K; Holtrop, M; Ilieva, Y; Ireland, D G; Isupov, E L; Jawalkar, S S; Jo, H S; Joo, K; Keller, D; Khandaker, M; Khetarpal,; Kim, W; Klein, A; Klein, F J; Konczykowski, P; Kubarovsky, V; Kuhn, S E; Kuleshov, S V; Kuznetsov, V; Livingston, K; Lu, H Y; Markov, N; Mayer, M; McAndrew, J; McCracken, M E; McKInnon, B; Meyer, C A; Mineeva, T; Mirazita, M; Mokeev, V; Moreno, B; Moriya, K; Morrison, B; Moutarde, H; Munevar, E; Nadel-Turonski, P; Nasseripour, R; Niccolai, S; Niculescu, G; Niculescu, I; Niroula, M R; Osipenko, M; Ostrovidov, A I; Paremuzyan, R; Park, K; Park, S; Pasyuk, E; Anefalos Pereira, S; Perrin, Y; Pisano, S; Pogorelko, O; Price, J W; Procureur, S; Prok, Protopopescu; Raue, B A; Ricco, G; Ripani, M; Rosner, G; Rossi, P; Sabatie, F; Saini, M S; Salamanca, J; Salgado, C; Schumacher, R A; Seder, E; Seraydaryan, H; Sharabian, Y G; Sober, D I; Sokhan, D; Stapanyan, S S; Stepanyan, S; Stoler, P; Strauch, S; Suleiman, R; Taiuti, M; Tedeschi, D J; Tkachenko, S; Ungaro, M; Vernarsky, B; Vineyard, M F; Voutier, E; Watts, D P; Weinstein, L B; Weygand, D P; Wood, M H; Zhang, J; Zhao, B; Zhao, Z W

    2010-12-01

    We report the first measurement of the transverse momentum dependence of double spin asymmetries in semi-inclusive production of pions in deep inelastic scattering off the longitudinally polarized proton. Data have been obtained using a polarized electron beam of 5.7 GeV with the CLAS detector at the Thomas Jefferson National Accelerator Facility (JLab). A significant non-zero $\\sin2\\phi$ single spin asymmetry was also observed for the first time indicating strong spin-orbit correlations for transversely polarized quarks in the longitudinally polarized proton. The azimuthal modulations of single spin asymmetries have been measured over a wide kinematic range.

  19. Measuring Changes in the Economics of Medical Practice.

    PubMed

    Fleming, Christopher; Rich, Eugene; DesRoches, Catherine; Reschovsky, James; Kogan, Rachel

    2015-08-01

    For the latter third of the twentieth century, researchers have estimated production and cost functions for physician practices. Today, those attempting to measure the inputs and outputs of physician practice must account for many recent changes in models of care delivery. In this paper, we review practice inputs and outputs as typically described in research on the economics of medical practice, and consider the implications of the changing organization of medical practice and nature of physician work. This evolving environment has created conceptual challenges in what are the appropriate measures of output from physician work, as well as what inputs should be measured. Likewise, the increasing complexity of physician practice organizations has introduced challenges to finding the appropriate data sources for measuring these constructs. Both these conceptual and data challenges pose measurement issues that must be overcome to study the economics of modern medical practice. Despite these challenges, there are several promising initiatives involving data sharing at the organizational level that could provide a starting point for developing the needed new data sources and metrics for physician inputs and outputs. However, additional efforts will be required to establish data collection approaches and measurements applicable to smaller and single specialty practices. Overcoming these measurement and data challenges will be key to supporting policy-relevant research on the changing economics of medical practice. PMID:26105674

  20. Longitudinal measurements of postnatal rat brain mechanical properties in-vivo.

    PubMed

    Pong, Alice C; Jugé, Lauriane; Cheng, Shaokoon; Bilston, Lynne E

    2016-06-14

    Information on pediatric brain tissue mechanical properties and, more pertinently, how they change during postnatal development remains scarce despite its importance to investigate mechanisms of neural injury. The aim of this study is to determine whether brain mechanical properties change in-vivo during early postnatal development in a rat model. Rat brain viscoelastic properties were measured longitudinally in ten healthy Sprague Dawley rats at five different time points from postnatal week one to week six using magnetic resonance elastography at 800Hz. Myelination and cell density were assessed histologically at the same time points to understand how the underlying tissue microstructure may be associated with changes in mechanical properties at different brain regions. Longitudinal changes in each variable were assessed using a generalized linear model with pairwise comparisons of means between weeks. The brain shear modulus in the cortical gray matter at postnatal week one was 6.3±0.4kPa, and increased significantly from week one to week two (pairwise comparison, p<0.01), remained stable from week two to week four and decreased significantly by week six (pairwise comparison, p<0.001). In the deep gray matter, brain tissue stiffness at postnatal week one was 6.1±2.0kPa, and increased significantly from one to week four (pairwise comparison, p<0.05) before decreasing significantly by week six (pairwise comparison, p<0.001). Stiffness changes were not directly correlated to histological observations. These data suggest that brain tissue shear modulus initially increases during a period equivalent to early childhood, and then decreases during a period equivalent to adolescence. PMID:27126986

  1. Measurements of longitudinal gamma ray distribution using a multichannel fiber-optic Cerenkov radiation sensor

    NASA Astrophysics Data System (ADS)

    Shin, S. H.; Jeon, D.; Kim, J. S.; Jang, J. S.; Jang, K. W.; Yoo, W. J.; Moon, J. H.; Park, B. G.; Kim, S.; Lee, B.

    2014-11-01

    Cerenkov radiation occurs when charged particles are moving faster than the speed of light in a transparent dielectric medium. In optical fibers, Cerenkov radiation can also be generated due to the fiber’s dielectric components. Accordingly, the radiation-induced light signals can be obtained using the optical fibers without any scintillating material. In this study, we fabricated a multichannel, fiber-optic Cerenkov radiation sensor (FOCRS) system using silica optical fibers (SOFs), plastic optical fibers (POFs), an optical spectrometer, multi-anode photomultiplier tubes (MA-PMTs) and a scanning system to measure the light intensities of Cerenkov radiation induced by gamma rays. To evaluate the fading effects in optical fibers, the spectra of Cerenkov radiation generated in the SOFs and POFs were measured based on the irradiation time by using an optical spectrometer. In addition, we measured the longitudinal distribution of gamma rays emitted from the cylindrical type Co-60 source by using MA-PMTs. The result was also compared with the distribution of the electron flux calculated by using the Monte Carlo N-particle transport code (MCNPX).

  2. Measuring Service Quality: From Theory into Practice.

    ERIC Educational Resources Information Center

    Calvert, Philip J.

    1997-01-01

    Academic library managers need a multimethod, objective, valid tool for measuring service quality. Examines three research studies in the measurement of service quality in Australian and New Zealand academic libraries: the Hernon and Altman Study; Hernon and Calvert Study; and the University of Waikato (Hamilton, New Zealand) Survey, a two-stage…

  3. Impact of College-Administered Quality Practice Assessments: A Longitudinal Evaluation of Repeat Peer Assessments of Continuing Competence in Physiotherapists

    PubMed Central

    O'Donovan, Mary Jane; Campbell, Fiona

    2015-01-01

    ABSTRACT Purpose: The College of Physiotherapists of Ontario (CPO) developed its peer practice assessment (PA) process under statutory requirements for quality assurance. Each year, a small percentage of physiotherapists, most selected at random, undergo PA. To shed light on continuing competence, we report outcomes from physiotherapists who have had two PAs. Methods: Records were extracted for physiotherapists with two unrelated PAs. Demographic features, peer assessors' scores, and consequent outcome decisions were examined. Outcomes were examined cross-sectionally (vs. other PAs in the same time period) and longitudinally (within cohort). Results: Between 2004 and 2012, 117 Ontario physiotherapists underwent two unrelated PAs, typically 5–7 years apart. This cohort was representative of Ontario physiotherapists in terms of sex ratios, education, and years in practice. At the first PA (PA1), this cohort's outcomes were similar to those of other physiotherapists; at the second PA (PA2), they were better than others undergoing PA1 in the same period (p=0.02). The cohort's outcomes were better at PA2 than at PA1 (p<0.001). Conclusions: Physiotherapists are likely to meet professional standards in a repeat PA 5–7 years after an initial one. Additional research is required to identify risk factors for not meeting standards. The findings provide empirical evidence to guide ongoing development of the CPO's quality management program. PMID:25931670

  4. Maternal feeding styles and food parenting practices as predictors of longitudinal changes in weight status in Hispanic preschoolers from low-income families

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The aim was to investigate the influence of feeding styles and food parenting practices on low-income children's weight status over time. Participants were 129 Latina parents and their Head Start children participating in a longitudinal study. Children were assessed at baseline (4 to 5 years old) an...

  5. Underlying Factors of Family Literacy Practices as Antecedents of Reading Achievement: A Longitudinal, Factorial, Multiple Regression Study Using ECLS-K Data

    ERIC Educational Resources Information Center

    Fisher, Stacey Jonell

    2011-01-01

    The study had twofold purposes. The first one is to establish the underlying structure of family literacy practices at the different grade levels kindergarten, first, third, fifth, and eighth, for children who were followed in the Early Childhood Longitudinal Study, Kindergarten Class of 1998-1999 (ECLS-K). The second purpose is to investigate the…

  6. National Educational Technology Standards and Technology Beliefs and Practices of Social Studies Faculty: Results from a Seven-Year Longitudinal Study

    ERIC Educational Resources Information Center

    Friedman, Adam; Bolick, Cheryl; Berson, Michael; Porfeli, Erik

    2009-01-01

    This paper presents the findings from the third survey administration of a longitudinal study that explores the beliefs, practices, and efficacy of social studies faculty members from across the United States in terms of instructional technology use. The findings of this study demonstrate that familiarity with the "National Educational Technology…

  7. Maternal Feeding Styles and Food Parenting Practices as Predictors of Longitudinal Changes in Weight Status in Hispanic Preschoolers from Low-Income Families

    PubMed Central

    O'Connor, Teresia M.; Orlet Fisher, Jennifer

    2016-01-01

    Objective. The aim was to investigate the influence of feeding styles and food parenting practices on low-income children's weight status over time. Method. Participants were 129 Latina parents and their Head Start children participating in a longitudinal study. Children were assessed at baseline (4 to 5 years old) and again eighteen months later. At each time point, parents completed questionnaires and height and weight measures were taken on the child. Results. The indulgent feeding style (parent-report at baseline) was associated with increased child BMI z-score eighteen months later compared to other feeding styles. Authoritative, authoritarian, and uninvolved feeding styles were not significantly associated with increased child BMI z-score. Child BMI z-score at Time 1 (strongest) and maternal acculturation were positive predictors of child BMI z-score at Time 2. Maternal use of restriction positively predicted and maternal monitoring negatively predicted Time 2 BMI z-score, but only when accounting for feeding styles. Conclusion. This is the first study to investigate the impact of feeding styles on child weight status over time. Results suggest that indulgent feeding predicts later increases in children's weight status. The interplay between feeding styles and food parenting practices in influencing child weight status needs to be further explored. PMID:27429801

  8. Maternal Feeding Styles and Food Parenting Practices as Predictors of Longitudinal Changes in Weight Status in Hispanic Preschoolers from Low-Income Families.

    PubMed

    Hughes, Sheryl O; Power, Thomas G; O'Connor, Teresia M; Orlet Fisher, Jennifer; Chen, Tzu-An

    2016-01-01

    Objective. The aim was to investigate the influence of feeding styles and food parenting practices on low-income children's weight status over time. Method. Participants were 129 Latina parents and their Head Start children participating in a longitudinal study. Children were assessed at baseline (4 to 5 years old) and again eighteen months later. At each time point, parents completed questionnaires and height and weight measures were taken on the child. Results. The indulgent feeding style (parent-report at baseline) was associated with increased child BMI z-score eighteen months later compared to other feeding styles. Authoritative, authoritarian, and uninvolved feeding styles were not significantly associated with increased child BMI z-score. Child BMI z-score at Time 1 (strongest) and maternal acculturation were positive predictors of child BMI z-score at Time 2. Maternal use of restriction positively predicted and maternal monitoring negatively predicted Time 2 BMI z-score, but only when accounting for feeding styles. Conclusion. This is the first study to investigate the impact of feeding styles on child weight status over time. Results suggest that indulgent feeding predicts later increases in children's weight status. The interplay between feeding styles and food parenting practices in influencing child weight status needs to be further explored. PMID:27429801

  9. TIME-DEPENDENT PHASE SPACE MEASUREMENTS OF THE LONGITUDINALLY COMPRESSING BEAM IN NDCX-I

    SciTech Connect

    LBNL; Lidia, S.M.; Bazouin, G.; Seidl, P.A.

    2011-03-15

    The Neutralized Drift Compression Experiment (NDCXI) generates high intensity ion beams to explore Warm Dense Matter physics. A {approx}150 kV, {approx}500 ns modulating voltage pulse is applied to a {approx}300 kV, 5-10 {mu}s, 25 mA K+ ion beam across a single induction gap. The velocity modulated beam compresses longitudinally during ballistic transport along a space charge neutralizing plasma transport line, resulting in {approx}3A peak current with {approx}2-3 ns pulse durations (FWHM) at the target plane. Transverse final focusing is accomplished with a {approx}8 T, 10 cm long pulsed solenoid magnet. Time-dependent electrostatic focusing in the induction gap, and chromatic aberrations in the final focus optics limit the peak fluenceat the target plane for the compressed beam pulse. We report on time-dependent phase space measurements of the compressed pulse in the ballistic transport beamline, and measurement of the time-dependent radial impulses derived from the interaction of the beam and the induction gap voltage. We present results of start-to-end simulations to benchmark the experiments. Fast correction strategies are discussed with application to both NDCX-I and the soon to be commissioned NDCX-II accelerators.

  10. Longitudinal detection of ferromagnetic resonance using x-ray transmission measurements

    SciTech Connect

    Boero, G.; Rusponi, S.; Kavich, J.; Rizzini, A. Lodi; Piamonteze, C.; Nolting, F.; Tieg, C.; Thiele, J.-U.; Gambardella, P.

    2009-12-15

    We describe a setup for the x-ray detection of ferromagnetic resonance in the longitudinal geometry using element-specific transmission measurements. Thin magnetic film samples are placed in a static magnetic field collinear with the propagation direction of a polarized soft x-ray beam and driven to ferromagnetic resonance by a continuous wave microwave magnetic field perpendicular to it. The transmitted photon flux is measured both as a function of the x-ray photon energy and as a function of the applied static magnetic field. We report experiments performed on a 15 nm film of doped Permalloy (Ni{sub 73}Fe{sub 18}Gd{sub 7}Co{sub 2}) at the L{sub 3}/L{sub 2}-edges of Fe, Co, and Ni. The achieved ferromagnetic resonance sensitivity is about 0.1 monolayers/{radical}(Hz). The obtained results are interpreted in the framework of a conductivity tensor based formalism. The factors limiting the sensitivity as well as different approaches for the x-ray detection of ferromagnetic resonance are discussed.

  11. Development and Validation of Army Selection and Classification Measures. Project A: Longitudinal Research Database Plan. Research Report 1356.

    ERIC Educational Resources Information Center

    Wise, Lauress L.; And Others

    This report describes plans for the development of a major longitudinal research database designed to support the development and validation of new predictors of Army performance, and also new measures of Army performance against which the new predictors can be validated. The following aspects of the database are addressed: (1) the anticipated…

  12. Concurrent and Longitudinal Patterns and Trends in Performance on Early Numeracy Curriculum-Based Measures in Kindergarten through Third Grade

    ERIC Educational Resources Information Center

    Missall, Kristen N.; Mercer, Sterett H.; Martinez, Rebecca S.; Casebeer, Dian

    2012-01-01

    The purpose of this study was to extend the research on the "Tests of Early Numeracy Curriculum-Based Measurement" (TEN-CBM) tools by examining concurrent and predictive relations from kindergarten through third grade. Using a longitudinal sample of 535 students, this study included logistic regression, latent cluster, and latent transition…

  13. Measuring international migration: theory and practice.

    PubMed

    Zlotnik, H

    1987-01-01

    This volume is the result of the collaboration between the INTERNATIONAL MIGRATION REVIEW and 2 of the scientific committees of the International Union for the Scientific Study of Population. The Committee on International Migration and the Committee on Data Collection and processing in developing countries jointly organized a workshop entitled "International Migration Statistics: Their Problems and Use" that took place in Ottawa, Canada from November 11-13, 1987. Preliminary versions of about 1/2 of the articles contained in this volume were presented at that workshop. A full report of the discussions that took place at the workshop is also included here. The 43 items contained in this report are grouped under the following headings: Concepts, Developments and Policy; Multilateral Efforts for the Measurement of International Migration; Research Notes; National Statistical Systems: Case Studies; Methodological Approaches; Conference Report; and Book reviews. The articles contained in this volume constitute a valuable contribution to the area of migration research concerned with the measurement and quantification of the phenomenon. They reflect the growing interest of the research community on measurement issues inextricably linked to the complex nature of international population movements. In their coverage of a variety of topics, several leitmotifs can be detected. Brief descriptions of a few that deserve to be singled out as challenges that still remain to be met by those interested in improving the data and the methods used to measure migration follow. 1) Flexibility might be enhanced by gathering and coding detailed information on certain items so as to allow their varied exploitation at a later date. Ease of access to the basic data gathered, through samples and computer-readable media, is another important means of increasing flexibility in the exploitation of existing data sources. Flexibility in the use of available statistics should also be pursued

  14. Longitudinal Measurement of Extracellular Matrix Rigidity in 3D Tumor Models Using Particle-tracking Microrheology

    PubMed Central

    El-Hamidi, Hamid; Celli, Jonathan P.

    2014-01-01

    The mechanical microenvironment has been shown to act as a crucial regulator of tumor growth behavior and signaling, which is itself remodeled and modified as part of a set of complex, two-way mechanosensitive interactions. While the development of biologically-relevant 3D tumor models have facilitated mechanistic studies on the impact of matrix rheology on tumor growth, the inverse problem of mapping changes in the mechanical environment induced by tumors remains challenging. Here, we describe the implementation of particle-tracking microrheology (PTM) in conjunction with 3D models of pancreatic cancer as part of a robust and viable approach for longitudinally monitoring physical changes in the tumor microenvironment, in situ. The methodology described here integrates a system of preparing in vitro 3D models embedded in a model extracellular matrix (ECM) scaffold of Type I collagen with fluorescently labeled probes uniformly distributed for position- and time-dependent microrheology measurements throughout the specimen. In vitro tumors are plated and probed in parallel conditions using multiwell imaging plates. Drawing on established methods, videos of tracer probe movements are transformed via the Generalized Stokes Einstein Relation (GSER) to report the complex frequency-dependent viscoelastic shear modulus, G*(ω). Because this approach is imaging-based, mechanical characterization is also mapped onto large transmitted-light spatial fields to simultaneously report qualitative changes in 3D tumor size and phenotype. Representative results showing contrasting mechanical response in sub-regions associated with localized invasion-induced matrix degradation as well as system calibration, validation data are presented. Undesirable outcomes from common experimental errors and troubleshooting of these issues are also presented. The 96-well 3D culture plating format implemented in this protocol is conducive to correlation of microrheology measurements with therapeutic

  15. Measures of the Effects of Agricultural Practices on Ecosystem Services

    SciTech Connect

    Dale, Virginia H; Polasky, Stephen

    2007-01-01

    Agriculture produces more than just crops. Agricultural practices have environmental impacts that affect a wide range of ecosystem services, including water quality, pollination, nutrient cycling, soil retention, carbon sequestration, and biodiversity conservation. In turn, ecosystem services affect agricultural productivity. Understanding the contribution of various agricultural practices to the range of ecosystem services would help inform choices about the most beneficial agricultural practices. To accomplish this, however, we must overcome a big challenge in measuring the impact of alternative agricultural practices on ecosystem services and of ecosystem services on agricultural production.

  16. Monitoring herd incidence of intramammary infection in lactating cows using repeated longitudinal somatic cell count measurements.

    PubMed

    Dufour, S; Dohoo, I R

    2013-03-01

    The objective of the study was to evaluate the ability of an estimate of the herd intramammary infection (IMI) incidence rate computed using repeated somatic cell count (SCC) measurements (quarter- and composite-SCC; hereafter, the SCC-derived herd IMI incidence, SCCI)to predict the incidence rate computed using repeated quarter-milk bacteriological culture (hereafter, bacteriological culture incidence, BCI) during the lactating period. A cohort of 91 Canadian dairy herds was followed in 2007 and 2008. In each herd and at each of 4 sampling periods, a series of 3 to 7 quarter-milk samples was collected from a sample of 15 cows. Routine milk bacteriological culture was conducted to identify IMI, SCC was measured on the quarter-milk samples, and composite-SCC of the preceding and following dairy herd improvement (DHI) tests were obtained. Mastitis pathogens were grouped in 3 categories: major, minor, and any pathogens. For each herd and for each period, BCI was computed for each group of organisms. Similarly, SCCI were computed using quarter- and DHI composite-SCC and using a threshold of 200,000 cells/mL to define infected quarters or cows. A linear regression model taking into account the structure of the data was used to compare the SCCI to the BCI. A similar model was used to compare fluctuations (i.e., changes from one sampling period to the next) over time of the SCCI and BCI. Measures of correlation between observed and predicted rates were computed and limits of agreement plots sketched to better explore the predictive ability of the SCCI. The quarter-milk SCC measurements that could be obtained-for instance, using on-line milking system measurements-appeared to be particularly valuable. Quarter-SCCI showed a positive and significant association with the BCI. However, limits of agreement plots indicated important disagreement for the small proportion of observations with very high BCI. Quarter-level SCCI and BCI fluctuations were also significantly associated

  17. First Measurements of the Longitudinal Bunch Profile at SLAC Using Coherent Smith-Purcell Radiation at 28GeV

    SciTech Connect

    Blackmore, V.; Doucas, G.; Ottewell, B.; Perry, C.; Kimmitt, M.F.; Arnold, R.; Molloy, S.; Woods, M.; /SLAC

    2011-11-02

    Coherent Smith-Purcell radiation has been demonstrated as a technique for measuring the longitudinal profile of charged particles bunches in the low to intermediate energy range. However, with the advent of the International Linear Collider, the need has arisen for a non-invasive method of measuring the bunch profile at extremely high energies. Smith-Purcell radiation has been used for the first time in the multi-GeV regime to measure the longitudinal profile of the 28GeV SLAC beam. The experiment has both successfully determined the bunch length, and has also demonstrated its sensitivity to bunch profile changes. The challenges associated with this technique, and its prospects as a diagnostic tool are reported here.

  18. Response shifts in mental health interventions: an illustration of longitudinal measurement invariance.

    PubMed

    Fokkema, Marjolein; Smits, Niels; Kelderman, Henk; Cuijpers, Pim

    2013-06-01

    The efficacy of treatments for depression is often measured by comparing observed total scores on self-report inventories, in both clinical practice and research. However, the occurrence of response shifts (changes in subjects' values, or their standards for measurement) may limit the validity of such comparisons. As most psychological treatments for depression are aimed at changing patients' values and frame of reference, response shifts are likely to occur over the course of such treatments. In this article, we tested whether response shifts occurred over the course of treatment in an influential randomized clinical trial. Using confirmatory factor analysis, measurement models underlying item scores on the Beck Depression Inventory (Beck & Beamesderfer, 1974) of the National Institute of Mental Health Treatment of Depression Collaborative Research Program (Elkin, Parloff, Hadley, & Autry, 1985) were analyzed. Compared with before treatment, after-treatment item scores appeared to overestimate depressive symptomatology, measurement errors were smaller, and correlations between constructs were stronger. These findings indicate a response shift, in the sense that participants seem to get better at assessing their level of depressive symptomatology. Comparing measurement models of patients receiving psychotherapy and medication suggested that the aforementioned effects were more apparent in the psychotherapy groups. Consequently, comparisons of observed total scores on self-report inventories may yield confounded measures of treatment efficacy. PMID:23339313

  19. Measuring student engagement in science classrooms: An investigation of the contextual factors and longitudinal outcomes

    NASA Astrophysics Data System (ADS)

    Spicer, Justina Judy

    This dissertation includes three separate but related studies that examine the different dimensions of student experiences in science using data from two different datasets: the High School Longitudinal Study of 2009 (HSLS:09), and a dataset constructed using the Experience Sampling Method (ESM). This mixed-dataset approach provides a unique perspective on student engagement and the contexts in which it exists. Engagement is operationalized across the three studies using aspects of flow theory to evaluate how the challenges in science classes are experienced at the student level. The data provides information on a student's skill-level and efficacy during the challenge, as well as their interest level and persistence. The data additionally track how situations contribute to optimal learning moments, along with longitudinal attitudes and behaviors towards science. In the first part of this study, the construct of optimal moments is explored using in the moment data from the ESM dataset. Several different measures of engagement are tested and validated to uncover relationships between various affective states and optimal learning experiences with a focus on science classrooms. Additional analyses include investigating the links between in the moment engagement (situational), and cross-situational (stable) measures of engagement in science. The second part of this dissertation analyzes the ESM data in greater depth by examining how engagement varies across students and their contextual environment. The contextual characteristics associated with higher engagement levels are evaluated to see if these conditions hold across different types of students. Chapter three more thoroughly analyzes what contributes to students persisting through challenging learning moments, and the variation in levels of effort put forth when facing difficulty while learning in science. In chapter four, this dissertation explores additional outcomes associated with student engagement in science

  20. Measurement of single- and double-spin asymmetries in deep inelastic pion electroproduction with a longitudinally polarized target.

    PubMed

    Avakian, H; Bosted, P; Burkert, V D; Elouadrhiri, L; Adhikari, K P; Aghasyan, M; Amaryan, M; Anghinolfi, M; Baghdasaryan, H; Ball, J; Battaglieri, M; Bedlinskiy, I; Biselli, A S; Branford, D; Briscoe, W J; Brooks, W; Carman, D S; Casey, L; Cole, P L; Collins, P; Crabb, D; Crede, V; D'Angelo, A; Daniel, A; Dashyan, N; De Vita, R; De Sanctis, E; Deur, A; Dey, B; Dhamija, S; Dickson, R; Djalali, C; Dodge, G; Doughty, D; Dupre, R; El Alaoui, A; Eugenio, P; Fegan, S; Fersch, R; Forest, T A; Fradi, A; Gabrielyan, M Y; Gavalian, G; Gevorgyan, N; Gilfoyle, G P; Giovanetti, K L; Girod, F X; Gohn, W; Gothe, R W; Griffioen, K A; Guidal, M; Guler, N; Guo, L; Hafidi, K; Hakobyan, H; Hanretty, C; Hassall, N; Heddle, D; Hicks, K; Holtrop, M; Ilieva, Y; Ireland, D G; Isupov, E L; Jawalkar, S S; Jo, H S; Joo, K; Keller, D; Khandaker, M; Khetarpal, P; Kim, W; Klein, A; Klein, F J; Konczykowski, P; Kubarovsky, V; Kuhn, S E; Kuleshov, S V; Kuznetsov, V; Livingston, K; Lu, H Y; Markov, N; Mayer, M; Martinez, D; McAndrew, J; McCracken, M E; McKinnon, B; Meyer, C A; Mineeva, T; Mirazita, M; Mokeev, V; Moreno, B; Moriya, K; Morrison, B; Moutarde, H; Munevar, E; Nadel-Turonski, P; Nasseripour, R; Niccolai, S; Niculescu, G; Niculescu, I; Niroula, M R; Osipenko, M; Ostrovidov, A I; Paremuzyan, R; Park, K; Park, S; Pasyuk, E; Pereira, S Anefalos; Perrin, Y; Pisano, S; Pogorelko, O; Price, J W; Procureur, S; Prok, Y; Protopopescu, D; Raue, B A; Ricco, G; Ripani, M; Rosner, G; Rossi, P; Sabatié, F; Saini, M S; Salamanca, J; Salgado, C; Schumacher, R A; Seder, E; Seraydaryan, H; Sharabian, Y G; Sober, D I; Sokhan, D; Stepanyan, S S; Stepanyan, S; Stoler, P; Strauch, S; Suleiman, R; Taiuti, M; Tedeschi, D J; Tkachenko, S; Ungaro, M; Vernarsky, B; Vineyard, M F; Voutier, E; Watts, D P; Weinstein, L B; Weygand, D P; Wood, M H; Zhang, J; Zhao, B; Zhao, Z W

    2010-12-31

    We report the first measurement of the transverse momentum dependence of double-spin asymmetries in semi-inclusive production of pions in deep-inelastic scattering off the longitudinally polarized proton. Data have been obtained using a polarized electron beam of 5.7 GeV with the CLAS detector at the Jefferson Lab (JLab). Modulations of single spin asymmetries over the azimuthal angle between lepton scattering and hadron production planes ϕ have been measured over a wide kinematic range in Bjorken x and virtual photon squared four-momentum Q2. A significant nonzero sin2ϕ single spin asymmetry was observed for the first time indicating strong spin-orbit correlations for transversely polarized quarks in the longitudinally polarized proton. PMID:21231647

  1. Measurement of Single- and Double-Spin Asymmetries in Deep Inelastic Pion Electroproduction with a Longitudinally Polarized Target

    SciTech Connect

    Avakian, H.; Bosted, P.; Burkert, V. D.; Elouadrhiri, L.; Brooks, W.; Carman, D. S.; Deur, A.; Guo, L.; Kubarovsky, V.; Nadel-Turonski, P.; Weygand, D. P.; Adhikari, K. P.; Amaryan, M.; Dodge, G.; Gavalian, G.; Guler, N.; Klein, A.; Kuhn, S. E.; Niroula, M. R.; Seraydaryan, H.

    2010-12-31

    We report the first measurement of the transverse momentum dependence of double-spin asymmetries in semi-inclusive production of pions in deep-inelastic scattering off the longitudinally polarized proton. Data have been obtained using a polarized electron beam of 5.7 GeV with the CLAS detector at the Jefferson Lab (JLab). Modulations of single spin asymmetries over the azimuthal angle between lepton scattering and hadron production planes {phi} have been measured over a wide kinematic range in Bjorken x and virtual photon squared four-momentum Q{sup 2}. A significant nonzero sin2{phi} single spin asymmetry was observed for the first time indicating strong spin-orbit correlations for transversely polarized quarks in the longitudinally polarized proton.

  2. Atmospheric lateral and longitudinal turbulent length scales (measured at 600 to 800 meters above grade level)

    NASA Technical Reports Server (NTRS)

    Cliff, W. C.; Skarda, J. R.

    1987-01-01

    NASA's Airborne Doppler Lidar System has been used to obtain a detailed 'instantaneous' mapping of horizontal spatial wind fields at 600-800 m elevations on the east side of the San Gorgonio Pass in California, in the form of checkerboard-fashion horizontal wind vectors spaced at 300 m intervals along and normal to the flight path. Spatial autocorrelations for the lateral and longitudinal components are ensemble-averaged, and integral turbulent length scales are computed for the wind fields' longitudinal and lateral directions. The flow in the region studied does not appear to be isotropic.

  3. Parenting Practices and Perceived Social Support: Longitudinal Relations with the Social Competence of Mexican-origin Children

    PubMed Central

    Taylor, Zoe E.; Conger, Rand D.; Robins, Richard W.; Widaman, Keith F.

    2015-01-01

    Social bonds and supportive relationships are widely recognized as being indispensable to healthy psychological functioning and well-being. Social support is a psychological resource that is expected to also contribute positively to parenting practices. The present study longitudinally examined the relations between mothers’ (N = 674) and fathers’ (N = 430) perceived social support and parenting behaviors, and their relations with children’s social competence during early adolescence in Mexican-origin single and two-parent families. Our constructs of interest (warm parenting, monitoring, perceived social support, and children’s social competence) were significantly correlated at T1, and demonstrated significant stability across time for both parental models. Parental warmth (as reported by the child, and opposite parent) and parental monitoring (self-reported by mothers and fathers) were correlated and also showed bidirectional associations across time. Parental monitoring at T2 positively predicted change in children’s social competence at T3 (controlling for T1 social competence) for mothers. Parental warmth at T2 positively predicted change in children’s social competence at T3 (controlling for T1 social competence) for fathers. For mothers, the indirect effect of social support at T1 on children’s social competence at T3 via parental monitoring at T2 (and controlling for prior levels) was significant. Findings suggest that maternal perceived social support contributes to children’s social competence due to its positive relation to maternal monitoring. Results may also suggest that mothers’ and fathers’ parenting behaviors differentially relate to children’s social competence in Latino families, although additional work focused on comparing parenting behaviors in two-parent families is needed. PMID:26751039

  4. Alternative Measures of Teacher Performance. Policy-to-Practice Brief

    ERIC Educational Resources Information Center

    Potemski, Amy; Baral, Mahua; Meyer, Cassandra

    2011-01-01

    This Policy-to-Practice Brief introduces five current examples of measures of teacher performance. The goal is to assist regional comprehensive centers and state education agencies in building local capacity to incorporate the use of alternative measures of teacher performance into the overhaul of state evaluation systems--especially in states…

  5. Implementing Innovative Counseling Practices: Are School Counselors MEASUREing Up?

    ERIC Educational Resources Information Center

    Smith, Kimberly Nicole Tripp

    2012-01-01

    The purpose of this study was to examine school counselors' perception of how innovative counseling practices are or are not lived in a local school district. The eastern North Carolina school district was selected because MEASURE was being introduced in the district as a new way for program evaluation. The acronym MEASURE stands for Mission,…

  6. A method for noninvasive longitudinal measurements of [Ca2+] in arterioles of hypertensive optical biosensor mice

    PubMed Central

    Mauban, Joseph R. H.; Fairfax, Seth T.; Rizzo, Mark A.; Zhang, Jin

    2014-01-01

    We used two-photon (2-p) Förster resonance energy transfer (FRET) microscopy to provide serial, noninvasive measurements of [Ca2+] in arterioles of living “biosensor” mice. These express a genetically encoded Ca2+ indicator (GECI), either FRET-based exMLCK or intensity-based GCaMP2. The FRET ratios, Rmin and Rmax, required for in vivo Ca2+ calibration of exMLCK were obtained in isolated arteries. For in vivo experiments, mice were anesthetized (1.5% isoflurane), and arterioles within a depilated ear were visualized through the intact skin (i.e., noninvasively), by 2-p excitation of exMLCK (at 820 nm) or GCaMP2 (at 920 nm). Spontaneous or agonist-evoked [Ca2+] transients in arteriolar smooth muscle cells were imaged (at 2 Hz) with both exMLCK and GCaMP2. To examine changes in arteriolar [Ca2+] that might accompany hypertension, five exMLCK mice were implanted with telemetric blood pressure transducers and osmotic minipumps containing ANG II (350 ng·kg−1·min−1) and fed a high (6%)-salt diet for 9 days. [Ca2+] was measured every other day in five smooth muscle cells of two to three arterioles in each animal. Prior to ANG II/salt, [Ca2+] was 246 ± 42 nM. [Ca2+] increased transiently to 599 nM on day 2 after beginning ANG II/salt, then remained elevated at 331 ± 42 nM for 4 more days, before returning to 265 ± 47 nM 6 days after removal of ANG II/salt. In summary, two-photon excitation of exMLCK and GCaMP2 provides a method for noninvasive, longitudinal quantification of [Ca2+] dynamics and vascular structure in individual arterioles of a particular animal over an extended period of time, a capability that should enhance future studies of hypertension and vascular function. PMID:24858846

  7. Measurement of Longitudinal Spin Asymmetries for Weak Boson Production in Polarized Proton-Proton Collisions at RHIC

    NASA Astrophysics Data System (ADS)

    Adamczyk, L.; Adkins, J. K.; Agakishiev, G.; Aggarwal, M. M.; Ahammed, Z.; Alekseev, I.; Alford, J.; Anson, C. D.; Aparin, A.; Arkhipkin, D.; Aschenauer, E. C.; Averichev, G. S.; Balewski, J.; Banerjee, A.; Beavis, D. R.; Bellwied, R.; Bhasin, A.; Bhati, A. K.; Bhattarai, P.; Bichsel, H.; Bielcik, J.; Bielcikova, J.; Bland, L. C.; Bordyuzhin, I. G.; Borowski, W.; Bouchet, J.; Brandin, A. V.; Brovko, S. G.; Bültmann, S.; Bunzarov, I.; Burton, T. P.; Butterworth, J.; Caines, H.; Calderón de la Barca Sánchez, M.; Campbell, J. M.; Cebra, D.; Cendejas, R.; Cervantes, M. C.; Chaloupka, P.; Chang, Z.; Chattopadhyay, S.; Chen, H. F.; Chen, J. H.; Chen, L.; Cheng, J.; Cherney, M.; Chikanian, A.; Christie, W.; Chwastowski, J.; Codrington, M. J. M.; Contin, G.; Cramer, J. G.; Crawford, H. J.; Cui, X.; Das, S.; Davila Leyva, A.; De Silva, L. C.; Debbe, R. R.; Dedovich, T. G.; Deng, J.; Derevschikov, A. A.; Derradi de Souza, R.; Dhamija, S.; di Ruzza, B.; Didenko, L.; Dilks, C.; Ding, F.; Djawotho, P.; Dong, X.; Drachenberg, J. L.; Draper, J. E.; Du, C. M.; Dunkelberger, L. E.; Dunlop, J. C.; Efimov, L. G.; Engelage, J.; Engle, K. S.; Eppley, G.; Eun, L.; Evdokimov, O.; Eyser, O.; Fatemi, R.; Fazio, S.; Fedorisin, J.; Filip, P.; Finch, E.; Fisyak, Y.; Flores, C. E.; Gagliardi, C. A.; Gangadharan, D. R.; Garand, D.; Geurts, F.; Gibson, A.; Girard, M.; Gliske, S.; Greiner, L.; Grosnick, D.; Gunarathne, D. S.; Guo, Y.; Gupta, A.; Gupta, S.; Guryn, W.; Haag, B.; Hamed, A.; Han, L.-X.; Haque, R.; Harris, J. W.; Heppelmann, S.; Hirsch, A.; Hoffmann, G. W.; Hofman, D. J.; Horvat, S.; Huang, B.; Huang, H. Z.; Huang, X.; Huck, P.; Humanic, T. J.; Igo, G.; Jacobs, W. W.; Jang, H.; Judd, E. G.; Kabana, S.; Kalinkin, D.; Kang, K.; Kauder, K.; Ke, H. W.; Keane, D.; Kechechyan, A.; Kesich, A.; Khan, Z. H.; Kikola, D. P.; Kisel, I.; Kisiel, A.; Koetke, D. D.; Kollegger, T.; Konzer, J.; Koralt, I.; Kosarzewski, L. K.; Kotchenda, L.; Kraishan, A. F.; Kravtsov, P.; Krueger, K.; Kulakov, I.; Kumar, L.; Kycia, R. A.; Lamont, M. A. C.; Landgraf, J. M.; Landry, K. D.; Lauret, J.; Lebedev, A.; Lednicky, R.; Lee, J. H.; LeVine, M. J.; Li, C.; Li, W.; Li, X.; Li, X.; Li, Y.; Li, Z. M.; Lisa, M. A.; Liu, F.; Ljubicic, T.; Llope, W. J.; Lomnitz, M.; Longacre, R. S.; Luo, X.; Ma, G. L.; Ma, Y. G.; Madagodagettige Don, D. M. M. D.; Mahapatra, D. P.; Majka, R.; Margetis, S.; Markert, C.; Masui, H.; Matis, H. S.; McDonald, D.; McShane, T. S.; Minaev, N. G.; Mioduszewski, S.; Mohanty, B.; Mondal, M. M.; Morozov, D. A.; Mustafa, M. K.; Nandi, B. K.; Nasim, Md.; Nayak, T. K.; Nelson, J. M.; Nigmatkulov, G.; Nogach, L. V.; Noh, S. Y.; Novak, J.; Nurushev, S. B.; Odyniec, G.; Ogawa, A.; Oh, K.; Ohlson, A.; Okorokov, V.; Oldag, E. W.; Olvitt, D. L.; Pachr, M.; Page, B. S.; Pal, S. K.; Pan, Y. X.; Pandit, Y.; Panebratsev, Y.; Pawlak, T.; Pawlik, B.; Pei, H.; Perkins, C.; Peryt, W.; Pile, P.; Planinic, M.; Pluta, J.; Poljak, N.; Poniatowska, K.; Porter, J.; Poskanzer, A. M.; Pruthi, N. K.; Przybycien, M.; Pujahari, P. R.; Putschke, J.; Qiu, H.; Quintero, A.; Ramachandran, S.; Raniwala, R.; Raniwala, S.; Ray, R. L.; Riley, C. K.; Ritter, H. G.; Roberts, J. B.; Rogachevskiy, O. V.; Romero, J. L.; Ross, J. F.; Roy, A.; Ruan, L.; Rusnak, J.; Rusnakova, O.; Sahoo, N. R.; Sahu, P. K.; Sakrejda, I.; Salur, S.; Sandweiss, J.; Sangaline, E.; Sarkar, A.; Schambach, J.; Scharenberg, R. P.; Schmah, A. M.; Schmidke, W. B.; Schmitz, N.; Seger, J.; Seyboth, P.; Shah, N.; Shahaliev, E.; Shanmuganathan, P. V.; Shao, M.; Sharma, B.; Shen, W. Q.; Shi, S. S.; Shou, Q. Y.; Sichtermann, E. P.; Singaraju, R. N.; Skoby, M. J.; Smirnov, D.; Smirnov, N.; Solanki, D.; Sorensen, P.; Spinka, H. M.; Srivastava, B.; Stanislaus, T. D. S.; Stevens, J. R.; Stock, R.; Strikhanov, M.; Stringfellow, B.; Sumbera, M.; Sun, X.; Sun, X. M.; Sun, Y.; Sun, Z.; Surrow, B.; Svirida, D. N.; Symons, T. J. M.; Szelezniak, M. A.; Takahashi, J.; Tang, A. H.; Tang, Z.; Tarnowsky, T.; Thomas, J. H.; Timmins, A. R.; Tlusty, D.; Tokarev, M.; Trentalange, S.; Tribble, R. E.; Tribedy, P.; Trzeciak, B. A.; Tsai, O. D.; Turnau, J.; Ullrich, T.; Underwood, D. G.; Van Buren, G.; van Nieuwenhuizen, G.; Vandenbroucke, M.; Vanfossen, J. A.; Varma, R.; Vasconcelos, G. M. S.; Vasiliev, A. N.; Vertesi, R.; Videbæk, F.; Viyogi, Y. P.; Vokal, S.; Vossen, A.; Wada, M.; Wang, F.; Wang, G.; Wang, H.; Wang, J. S.; Wang, X. L.; Wang, Y.; Wang, Y.; Webb, G.; Webb, J. C.; Westfall, G. D.; Wieman, H.; Wissink, S. W.; Witt, R.; Wu, Y. F.; Xiao, Z.; Xie, W.; Xin, K.; Xu, H.; Xu, J.; Xu, N.; Xu, Q. H.; Xu, Y.; Xu, Z.; Yan, W.; Yang, C.; Yang, Y.; Yang, Y.; Ye, Z.; Yepes, P.; Yi, L.; Yip, K.; Yoo, I.-K.; Yu, N.; Zawisza, Y.; Zbroszczyk, H.; Zha, W.; Zhang, J. B.; Zhang, J. L.; Zhang, S.; Zhang, X. P.; Zhang, Y.; Zhang, Z. P.; Zhao, F.; Zhao, J.; Zhong, C.; Zhu, X.; Zhu, Y. H.; Zoulkarneeva, Y.; Zyzak, M.; STAR Collaboration

    2014-08-01

    We report measurements of single- and double-spin asymmetries for W± and Z/γ* boson production in longitudinally polarized p+p collisions at √s =510 GeV by the STAR experiment at RHIC. The asymmetries for W± were measured as a function of the decay lepton pseudorapidity, which provides a theoretically clean probe of the proton's polarized quark distributions at the scale of the W mass. The results are compared to theoretical predictions, constrained by polarized deep inelastic scattering measurements, and show a preference for a sizable, positive up antiquark polarization in the range 0.05

  8. Emotional Intelligence throughout Portuguese Secondary School: A Longitudinal Study Comparing Performance and Self-Report Measures

    ERIC Educational Resources Information Center

    Costa, Ana; Faria, Luísa

    2016-01-01

    This study examines the developmental trajectories of ability and trait emotional intelligence (EI) in the Portuguese secondary school. Within a three-wave longitudinal design, 395 students (M[subscript age] = 15.4; SD = 0.74) completed both the Emotional Skills and Competence Questionnaire (ESCQ) and the Vocabulary of Emotions Test (VET). Results…

  9. Constructing a Measure for Longitudinal Medical Achievement Studies by the Rasch Model One-Step Equating.

    ERIC Educational Resources Information Center

    Shen, Linjun

    As part of a longitudinal study of the growth of general medical knowledge among osteopathic medical students, a simple, convenient, and accurate vertical equating method was developed for constructing a scale for medical achievement. It was believed that Parts 1, 2, and 3 of the National Board of Osteopathic Medical Examiners' (NBOME) examination…

  10. Measuring Growth in a Longitudinal Large-Scale Assessment with a General Latent Variable Model

    ERIC Educational Resources Information Center

    von Davier, Matthias; Xu, Xueli; Carstensen, Claus H.

    2011-01-01

    The aim of the research presented here is the use of extensions of longitudinal item response theory (IRT) models in the analysis and comparison of group-specific growth in large-scale assessments of educational outcomes. A general discrete latent variable model was used to specify and compare two types of multidimensional item-response-theory…

  11. Measuring Puberty and Understanding Its Impact: A Longitudinal Study of Adolescent Twins.

    ERIC Educational Resources Information Center

    Dick, Danielle M.; Rose, Richard J.; Pulkkinen, Lea; Kaprio, Jaakko

    2001-01-01

    Established normative data on the Pubertal Development Scale (PDS) (A. Petersen and others, 1988) of two population-based birth cohorts of Finnish twin boys and girls assessed at ages 11-12 and 14 years (complete data for 664 boys and 681 girls). Also reports longitudinal analyses of the associations between pubertal development and substance use.…

  12. Nonresponse bias in a longitudinal measurement design examining substance use across the transition out of high school

    PubMed Central

    Griffin, Jamie; Patrick, Megan E.

    2014-01-01

    Background Intensive longitudinal methods are used to study the daily-level, within-person associations between substance use and its predictors and consequences. By definition, these designs require greater respondent effort than more traditional longitudinal designs, the result of which may be increased unit nonresponse and, more importantly, nonresponse bias. The present study contrasts the nonresponse properties of a measurement burst design with those of a single one-year follow-up (“control”) design, with a particular emphasis on the retention of young adults who did not plan to graduate from college. Methods High school seniors (N=318) from three Midwestern schools completed an in-school baseline survey in spring 2012. Respondents were then randomized into a measurement burst or control group. Four, eight, and twelve months after baseline, young adults in the measurement burst group received a 30-minute follow-up web survey, followed by 14 days of web-based daily surveys. Young adults in the control group received only a 30-minute follow-up web survey twelve months after baseline. Response rates, predictors of nonresponse, and relative nonresponse biases for measures of sociodemographics, college plans, and substance use were compared between the two measurement groups. Results Compared to the control design, the measurement burst design had greater relative nonresponse bias for statistics measuring substance use, but lower relative nonresponse bias for the statistic measuring college plans. Conclusion Intensive longitudinal methods have the potential to retain non-college attending young adults during the transition to adulthood. Nonresponse adjustment weights should be used to correct for any detected bias. PMID:25156225

  13. Longitudinal NMR parameter measurements of Japanese pear fruit during the growing process using a mobile magnetic resonance imaging system

    NASA Astrophysics Data System (ADS)

    Geya, Yuto; Kimura, Takeshi; Fujisaki, Hirotaka; Terada, Yasuhiko; Kose, Katsumi; Haishi, Tomoyuki; Gemma, Hiroshi; Sekozawa, Yoshihiko

    2013-01-01

    Longitudinal nuclear magnetic resonance (NMR) parameter measurements of Japanese pear fruit (Pyrus pyrifolia Nakai, Kosui) were performed using an electrically mobile magnetic resonance imaging (MRI) system with a 0.2 T and 16 cm gap permanent magnet. To measure the relaxation times and apparent diffusion coefficients of the pear fruit in relation to their weight, seven pear fruits were harvested almost every week during the cell enlargement period and measured in a research orchard. To evaluate the in situ relaxation times, six pear fruits were longitudinally measured for about two months during the same period. The measurements for the harvested samples showed good agreement with the in situ measurements. From the measurements of the harvested samples, it is clear that the relaxation rates of the pear fruits linearly change with the inverse of the linear dimension of the fruits, demonstrating that the relaxation mechanism is a surface relaxation. We therefore conclude that the mobile MRI system is a useful device for measuring the NMR parameters of outdoor living plants.

  14. Joint multiple imputation for longitudinal outcomes and clinical events that truncate longitudinal follow-up.

    PubMed

    Hu, Bo; Li, Liang; Greene, Tom

    2016-07-30

    Longitudinal cohort studies often collect both repeated measurements of longitudinal outcomes and times to clinical events whose occurrence precludes further longitudinal measurements. Although joint modeling of the clinical events and the longitudinal data can be used to provide valid statistical inference for target estimands in certain contexts, the application of joint models in medical literature is currently rather restricted because of the complexity of the joint models and the intensive computation involved. We propose a multiple imputation approach to jointly impute missing data of both the longitudinal and clinical event outcomes. With complete imputed datasets, analysts are then able to use simple and transparent statistical methods and standard statistical software to perform various analyses without dealing with the complications of missing data and joint modeling. We show that the proposed multiple imputation approach is flexible and easy to implement in practice. Numerical results are also provided to demonstrate its performance. Copyright © 2015 John Wiley & Sons, Ltd. PMID:26179943

  15. Charting patients' course: a comparison of statistics used to summarize patient course in longitudinal and repeated measures studies.

    PubMed

    Arndt, S; Turvey, C; Coryell, W H; Dawson, J D; Leon, A C; Akiskal, H S

    2000-01-01

    Investigators conducting longitudinal studies of psychiatric illnesses often analyze data based on psychiatric symptom scales that were administered at multiple time points. This study examines the statistical properties of seven indices that summarize patient long-term course. These indices can be used to compare differences between two or more groups or to test for changes in symptoms over time. They may also be treated as outcome measures and correlated with other clinical variables.The performance of each of the seven indices was assessed using data from two large ongoing studies of psychiatric patients: a longitudinal study of affective disorders and a longitudinal study of first-episode psychosis. These two datasets were subjected to bootstrapping techniques in order to calculate both type I error rates and statistical power for each summary statistic. Of the seven indices, Kendall's tau performed the best as a measure of patients' symptom course. Kendall's tau appears to offer more statistical power to detect change in course, yet its average type I error rate was comparable to the other indices. PMID:10758251

  16. Longitudinal design for sonographic measurement of median nerve swelling with controlled exposure to physical work using an animal model

    PubMed Central

    Roll, Shawn C.; Evans, Kevin D.; Volz, Kevin R.; Sommerich, Carolyn M.

    2013-01-01

    This study examined the feasibility of a longitudinal design to sonographically measure swelling of the median nerve due to controlled exposure to a work task and to evaluate the relationship of changes in morphology to diagnostic standards. Fifteen macaca fascicularis pinched a lever in various wrist positions at a self-regulated pace (8 hours/day, 5 days/week, 18–20 weeks). Nerve conduction velocity (NCV) and cross-sectional area (CSA) were obtained every two weeks from baseline through working and a 6-week recovery. Trending across all subjects showed that NCV slowed and CSA at the carpal tunnel increased in the working arm, while no changes were observed in CSA either at the forearm or for any measure in the non-working arm. There was a small negative correlation between NCV and CSA in the working arm. This study provides validation that swelling can be observed using a longitudinal design. Longitudinal human studies are needed to describe the trajectory of nerve swelling for early identification of median nerve pathology. PMID:24139197

  17. Practical Measures of Integrated Information for Time-Series Data

    PubMed Central

    Barrett, Adam B.; Seth, Anil K.

    2011-01-01

    A recent measure of ‘integrated information’, ΦDM, quantifies the extent to which a system generates more information than the sum of its parts as it transitions between states, possibly reflecting levels of consciousness generated by neural systems. However, ΦDM is defined only for discrete Markov systems, which are unusual in biology; as a result, ΦDM can rarely be measured in practice. Here, we describe two new measures, ΦE and ΦAR, that overcome these limitations and are easy to apply to time-series data. We use simulations to demonstrate the in-practice applicability of our measures, and to explore their properties. Our results provide new opportunities for examining information integration in real and model systems and carry implications for relations between integrated information, consciousness, and other neurocognitive processes. However, our findings pose challenges for theories that ascribe physical meaning to the measured quantities. PMID:21283779

  18. Cross-national and longitudinal investigation of a short measure of workaholism.

    PubMed

    Rantanen, Johanna; Feldt, Taru; Hakanen, Jari J; Kokko, Katja; Huhtala, Mari; Pulkkinen, Lea; Schaufeli, Wilmar

    2015-01-01

    The present study investigated the factor structure of the 10-item version of the Dutch Work Addiction Scale (DUWAS). The DUWAS-10 is intended to measure workaholism with two correlated factors: working excessively (WE) and working compulsively (WC). The factor structure of the DUWAS-10 was examined among multi-occupational samples from the Netherlands (n=9,010) and Finland (n=4,567) using confirmatory factor analysis (CFA). CFAs revealed that the expected correlated two-factor solution showed satisfactory fit to the data. However, a second-order factor solution, where WE comprised the first-order factors "working frantically" and "working long hours", and WC the first-order factors "obsessive work drive" and "unease if not working", showed significantly better fit to the data. The expectation of factorial group invariance of the second-order factor structure between the Dutch and Finnish samples was also supported. Moreover, factorial time invariance was observed across a two-year time lag in a sub-sample of Finnish managers (n=459). In conclusion, the DUWAS-10 was found to be a comprehensive measure of workaholism, meeting the criteria of factorial validity in multiple settings, and can thus be recommended for use in both research and practice. PMID:25382382

  19. Cross-national and longitudinal investigation of a short measure of workaholism

    PubMed Central

    RANTANEN, Johanna; FELDT, Taru; HAKANEN, Jari J; KOKKO, Katja; HUHTALA, Mari; PULKKINEN, Lea; SCHAUFELI, Wilmar

    2014-01-01

    Abstract: The present study investigated the factor structure of the 10-item version of the Dutch Work Addiction Scale (DUWAS). The DUWAS-10 is intended to measure workaholism with two correlated factors: working excessively (WE) and working compulsively (WC). The factor structure of the DUWAS-10 was examined among multi-occupational samples from the Netherlands (n=9,010) and Finland (n=4,567) using confirmatory factor analysis (CFA). CFAs revealed that the expected correlated two-factor solution showed satisfactory fit to the data. However, a second-order factor solution, where WE comprised the first-order factors “working frantically” and “working long hours”, and WC the first-order factors “obsessive work drive” and “unease if not working”, showed significantly better fit to the data. The expectation of factorial group invariance of the second-order factor structure between the Dutch and Finnish samples was also supported. Moreover, factorial time invariance was observed across a two-year time lag in a sub-sample of Finnish managers (n=459). In conclusion, the DUWAS-10 was found to be a comprehensive measure of workaholism, meeting the criteria of factorial validity in multiple settings, and can thus be recommended for use in both research and practice. PMID:25382382

  20. Measurement Practices: Methods for Developing Content-Valid Student Examinations.

    ERIC Educational Resources Information Center

    Bridge, Patrick D.; Musial, Joseph; Frank, Robert; Roe, Thomas; Sawilowsky, Shlomo

    2003-01-01

    Reviews the fundamental principles associated with achieving a high level of content validity when developing tests for students. Suggests that the short-term efforts necessary to develop and integrate measurement theory into practice will lead to long-term gains for students, faculty, and academic institutions. (Includes 21 references.)…

  1. Panel: Practical Issues in Implementing Software Reliability Measurement

    NASA Technical Reports Server (NTRS)

    Nikora, A.; Everett, B.; Munson, J.; Musa, J.; Schneidewind, N.; Vouk, M.

    1999-01-01

    Many ways of estimating software systems' reliability, or reliability-related quantities, have been developed over the past several years. In this panel, we discuss practical issues to be addressed in implementing software reliabilty measurement techniques in a production development environment.

  2. Assessing the Practical Equivalence of Conversions when Measurement Conditions Change

    ERIC Educational Resources Information Center

    Liu, Jinghua; Dorans, Neil J.

    2012-01-01

    At times, the same set of test questions is administered under different measurement conditions that might affect the psychometric properties of the test scores enough to warrant different score conversions for the different conditions. We propose a procedure for assessing the practical equivalence of conversions developed for the same set of test…

  3. 38 CFR 21.7674 - Measurement of practical training courses.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2011-07-01 2011-07-01 false Measurement of practical training courses. 21.7674 Section 21.7674 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) VOCATIONAL REHABILITATION AND EDUCATION Educational Assistance for Members of the Selected Reserve Course Assessment...

  4. Measuring Attitudes toward Acceptable and Unacceptable Parenting Practices

    ERIC Educational Resources Information Center

    Budd, Karen S.; Behling, Steven; Li, Yan; Parikshak, Sangeeta; Gershenson, Rachel A.; Feuer, Rachel; Danko, Christina M.

    2012-01-01

    This study investigated the properties of a new rating instrument, the Parenting Questionnaire (PQ), designed to measure attitudes about acceptable and unacceptable parenting practices. In Study 1, subject matter experts representing culturally diverse psychologists, parents, and college students were consulted to identify 110 items receiving high…

  5. Procedural Fidelity: An Analysis of Measurement and Reporting Practices

    ERIC Educational Resources Information Center

    Ledford, Jennifer R.; Wolery, Mark

    2013-01-01

    A systematic analysis was conducted of measurement and reporting practices related to procedural fidelity in single-case research for the past 30 years. Previous reviews of fidelity primarily reported whether fidelity data were collected by authors; these reviews reported that collection was variable, but low across journals and over time. Results…

  6. The role of environment in the development of reading skills: a longitudinal study of preschool and school-age measures.

    PubMed

    Molfese, Victoria J; Modglin, Arlene; Molfese, Dennis L

    2003-01-01

    The purpose of this study was to extend previous studies on the influence of environmental measures on intelligence scores by examining how proximal and distal measures of children's environments in the preschool period and in the primary-grade period are related to their performance on reading achievement tests. Reading performance was explored using two approaches. The first approach involved the identification of children within a longitudinal sample who had poor reading skills at 8 years of age. The second approach used the full range of reading scores to explore whether factors influencing poor reading were different from those influencing good reading. Participants were 113 children, including 35 children with poor reading skills, who were part of a longitudinal study of cognitive development. Socioeconomic status (SES), Home Observation for Measurement of the Environment (HOME) scores at 3 and 10 years of age, and school-administered and individually administered reading achievement scores were obtained. Both SES and HOME scores were found to be related to reading abilities, but preschool environment measures were more strongly and consistently related to and predictive of reading scores. Differences in the patterns of correlations and the results of the predictive models were found between the full sample and the poor readers. Variables other than proximal and distal measures of the environment are involved in the development of reading skills. PMID:15490892

  7. Measurements of the Neutron Longitudinal Spin Asymmetry A1n and Flavor Decomposition in the Valence Quark Region

    SciTech Connect

    Flay, David J.

    2014-08-01

    The current data for the nucleon-virtual photon longitudinal spin asymmetry A1 on the proton and neutron have shown that the ratio of the polarized-to-unpolarized down-quarkparton distribution functions,Dd=d, tends towards -1/2 at large x, in disagreement with the perturbative QCD prediction that Dd/d approaches 1 but more in line with constituent quark models. As a part of experiment E06-014 in Hall A of Jefferson Lab, double-spin asymmetries were measured in the scattering of a longitudinally polarized electron beam of energies 4.74 and 5.89 GeV from a longitudinally and transversely polarized 3He target in the deep inelastic scattering and resonance region, allowing for the extraction of the neutron asymmetry An1 and the ratios Dd/d and Du/u. We will discuss our analysis of the data and present results for A1 and g1/F1 on both 3He and the neutron, and the resulting quark ratios for the up and down quarks in the kinematic range of 0.2

  8. Measuring Physician Quality and Efficiency in an Era of Practice Transformation: PCMH as a Case Study

    PubMed Central

    Sandy, Lewis G.; Haltson, Heidi; Metfessel, Brent A.; Reese, Conway

    2015-01-01

    Practicing physicians face myriad challenges as health care undergoes considerable transformation, including advancing efforts to measure and report on physician quality and efficiency, as well as the growth of new care models such as Accountable Care Organizations and patient-centered medical homes (PCMHs). How do these transformational forces relate to one another? How should practicing physicians focus and prioritize their improvement efforts? This Special Report examines how physicians’ performance on quality and efficiency measures may interact with delivery reforms, focusing on the PCMH. We note that although the PCMH is a promising model, published evidence is mixed. Using data and experience from a large commercial insurer’s performance transparency and PCMH programs, we further report that longitudinal analysis of UnitedHealthcare’s PCMH program experience has shown favorable changes; however, cross-sectional analysis indicates that National Committee for Quality Assurance’s PCMH designation is positively associated with achieving program Quality benchmarks, but negatively associated with program Efficiency benchmarks. This example illustrates some key issues for physicians in the current environment, and we provide suggestions for physicians and other stakeholders on understanding and acting on information from physician performance measurement programs. PMID:25964406

  9. Predicting future weight status from measurements made in early childhood: a novel longitudinal approach applied to Millennium Cohort Study data

    PubMed Central

    Mead, E; Batterham, A M; Atkinson, G; Ells, L J

    2016-01-01

    Background/Objective: There are reports that childhood obesity tracks into later life. Nevertheless, some tracking statistics such as correlations do not quantify individual agreement, whereas others such as diagnostic test statistics can be difficult to translate into practice. We aimed to employ a novel analytic approach, based on ordinal logistic regression, to predict weight status of 11-year-old children from measurements at age 5 years. Subjects/Methods: The UK 1990 growth references were used to generate clinical weight status categories of 12 076 children enrolled in the Millennium Cohort Study. Using ordinal regression, we derived the predicted probability (percent chances) of 11-year-old children becoming underweight, normal weight, overweight, obese and severely obese from their weight status category at age 5 years. Results: The chances of becoming obese (including severely obese) at age 11 years were 5.7% (95% confidence interval: 5.2 to 6.2%) for a normal-weight 5-year-old child and 32.3% (29.8 to 34.8%) for an overweight 5-year-old child. An obese 5-year-old child had a 68.1% (63.8 to 72.5%) chance of remaining obese at 11 years. Severely obese 5-year-old children had a 50.3% (43.1 to 57.4%) chance of remaining severely obese. There were no substantial differences between sexes. Nondeprived obese 5-year-old boys had a lower probability of remaining obese than deprived obese boys: −21.8% (−40.4 to −3.2%). This association was not observed in obese 5-year-old girls, in whom the nondeprived group had a probability of remaining obese 7% higher (−15.2 to 29.2%). The sex difference in this interaction of deprivation and baseline weight status was therefore −28.8% (−59.3 to 1.6%). Conclusions: We have demonstrated that ordinal logistic regression can be an informative approach to predict the chances of a child changing to, or from, an unhealthy weight status. This approach is easy to interpret and could be applied to any longitudinal data set

  10. Integral T-Shaped Phantom-Dosimeter System to Measure Transverse and Longitudinal Dose Distributions Simultaneously for Stereotactic Radiosurgery Dosimetry

    PubMed Central

    Yoo, Wook Jae; Moon, Jinsoo; Jang, Kyoung Won; Han, Ki-Tek; Shin, Sang Hun; Jeon, Dayeong; Park, Jang-Yeon; Park, Byung Gi; Lee, Bongsoo

    2012-01-01

    A T-shaped fiber-optic phantom-dosimeter system was developed using square scintillating optical fibers, a lens system, and a CMOS image camera. Images of scintillating light were used to simultaneously measure the transverse and longitudinal distributions of absorbed dose of a 6 MV photon beam with field sizes of 1 × 1 and 3 × 3 cm2. Each optical fiber has a very small sensitive volume and the sensitive material is water equivalent. This allows the measurements of cross-beam profile as well as the percentage depth dose of small field sizes. In the case of transverse dose distribution, the measured beam profiles were gradually become uneven and the beam edge had a gentle slope with increasing depth of the PMMA phantom. In addition, the maximum dose values of longitudinal dose distribution for 6 MV photon beam with field sizes of 1 × 1 and 3 × 3 cm2 were found to be at a depth of approximately 15 mm and the percentage depth dose of both field sizes were nearly in agreement at the skin dose level. Based on the results of this study, it is anticipated that an all-in-one phantom-dosimeter can be developed to accurately measure beam profiles and dose distribution in a small irradiation fields prior to carrying out stereotactic radiosurgery. PMID:22778649

  11. Longitudinal measurements of MRI-T2 in boys with Duchenne muscular dystrophy: Effects of age and disease progression

    PubMed Central

    Willcocks, RJ; Arpan, IA; Forbes, SC; Lott, DJ; Senesac, CS; Senesac, E; Deol, J; Triplett, W; Baligand, C; Daniels, MJ; Sweeney, HL; Walter, GA; Vandenborne, K

    2014-01-01

    Duchenne muscular dystrophy (DMD) is characterized by in increased muscle damage and progressive replacement of muscle by noncontractile tissue. Both of these pathological changes can lengthen the MRI transverse proton relaxation time (T2). The current study measured longitudinal changes in T2 and its distribution in the lower leg of 16 boys with DMD (5–13 years, 15 ambulatory), 15 healthy controls (5–13 years). These muscles were chosen to allow extended longitudinal monitoring, due to their slow progression compared with proximal muscles in DMD. In the soleus muscle of boys with DMD, T2 and the percentage of pixels with an elevated T2 (≥2 SD above control mean T2) increased significantly over one year and two years, while the width of the T2 histogram increased over two years. Changes in soleus T2 variables were significantly greater in 9–13 year old compared with 5–8 year old boys with DMD. Significant correlations between the change in all soleus T2 variables over two years and the change in functional measures over two years were found. MRI measurement of muscle T2 in boys with DMD is sensitive to disease progression and shows promise as a clinical outcome measure. PMID:24491484

  12. Salvadoran Campesinos/as' Literacy Practices and Perceptions of the Benefits of Literacy: A Longitudinal Study with Former Literacy Participants

    ERIC Educational Resources Information Center

    Prins, Esther

    2010-01-01

    This article uses data from longitudinal, ethnographic research to examine how, six years after attending literacy classes, 12 adults in rural El Salvador used literacy, their perceptions of the temporary and longer-term psychosocial and economic benefits of literacy education, and their memories of literacy classes. The findings support prior…

  13. Middle-Class African American Adolescents' and Parents' Conceptions of Parental Authority and Parenting Practices: A Longitudinal Investigation.

    ERIC Educational Resources Information Center

    Smetana, Judith G.

    2000-01-01

    Examined longitudinally conceptions of parental authority and ratings of parental rules and decision-making among middle- class African American adolescents and their parents. Found that nearly all subjects affirmed parents' legitimate authority to regulate and children's obligation to comply regarding oral, conventional, prudential, friendship,…

  14. Utilizing Longitudinal Measures of Fetal Growth to Create a Standard Method to Assess the Impacts of Maternal Disease and Environmental Exposure

    PubMed Central

    Cantonwine, David E.; Ferguson, Kelly K.; Mukherjee, Bhramar; Chen, Yin-Hsiu; Smith, Nicole A.; Robinson, Julian N.; Doubilet, Peter M.; Meeker, John D.; McElrath, Thomas F.

    2016-01-01

    Impaired or suboptimal fetal growth is associated with an increased risk of perinatal morbidity and mortality. By utilizing readily available clinical data on the relative size of the fetus at multiple points in pregnancy, including delivery, future epidemiological research can improve our understanding of the impacts of maternal, fetal, and environmental factors on fetal growth at different windows during pregnancy. This study presents mean and standard deviation ultrasound measurements from a clinically representative US population that can be utilized for creating Z-scores to this end. Between 2006 and 2012, 18, 904 non-anomalous pregnancies that received prenatal care, first and second trimester ultrasound evaluations, and ultimately delivered singleton newborns at Brigham and Women’s hospital in Boston were used to create the standard population. To illustrate the utility of this standard, we created Z-scores for ultrasound and delivery measurements for a cohort study population and examined associations with factors known to be associated with fetal growth. In addition to cross-sectional regression models, we created linear mixed models and generalized additive mixed models to illustrate how these scores can be utilized longitudinally and for the identification of windows of susceptibility. After adjustment for a priori confounders, maternal BMI was positively associated with increased fetal size beginning in the second trimester in cross-sectional models. Female infants and maternal smoking were associated with consistently reduced fetal size in the longitudinal models. Maternal age had a non-significant association with increased size in the first trimester that was attenuated as gestation progressed. As the growth measurements examined here are widely available in contemporary obstetrical practice, these data may be abstracted from medical records by investigators and standardized with the population means presented here. This will enable easy extension

  15. Best Practices for Measuring Students’ Attitudes toward Learning Science

    PubMed Central

    Lovelace, Matthew; Brickman, Peggy

    2013-01-01

    Science educators often characterize the degree to which tests measure different facets of college students’ learning, such as knowing, applying, and problem solving. A casual survey of scholarship of teaching and learning research studies reveals that many educators also measure how students’ attitudes influence their learning. Students’ science attitudes refer to their positive or negative feelings and predispositions to learn science. Science educators use attitude measures, in conjunction with learning measures, to inform the conclusions they draw about the efficacy of their instructional interventions. The measurement of students’ attitudes poses similar but distinct challenges as compared with measurement of learning, such as determining validity and reliability of instruments and selecting appropriate methods for conducting statistical analyses. In this review, we will describe techniques commonly used to quantify students’ attitudes toward science. We will also discuss best practices for the analysis and interpretation of attitude data. PMID:24297288

  16. The interference of the model support mast with measurements of the longitudinal and lateral aerodynamic coefficients

    NASA Technical Reports Server (NTRS)

    Vandekreeke, C.; Verriere, J.; Quemard, G.

    1987-01-01

    The effects the single-bottom support masts used in the ONERA S1 and S4 wind tunnels have on aerodynamic data collected with scale model aircraft were examined experimentally and analytically. Systematic studies were performed on the flow characteristics around different diameters for the mounts. Scaling methods used to make data from one wind tunnel correspond to data from the other are described. Airbus 320 models were introduced into the tests and mast-body flow interactions were observed. A summary is presented of restrictions on the mast diameters, relative to cylindrical model diameters, which will minimize the effects the masts have on longitudinal and lateral aerodynamic stability data.

  17. Factorial Validity of the Decisional Involvement Scale as a Measure of Content and Context of Nursing Practice.

    PubMed

    Yurek, Leo A; Havens, Donna S; Hays, Spencer; Hughes, Linda C

    2015-10-01

    Decisional involvement is widely recognized as an essential component of a professional nursing practice environment. In recent years, researchers have added to the conceptualization of nurses' role in decision-making to differentiate between the content and context of nursing practice. Yet, instruments that clearly distinguish between these two dimensions of practice are lacking. The purpose of this study was to examine the factorial validity of the Decisional Involvement Scale (DIS) as a measure of both the content and context of nursing practice. This secondary analysis was conducted using data from a longitudinal action research project to improve the quality of nursing practice and patient care in six hospitals (N = 1,034) in medically underserved counties of Pennsylvania. A cross-sectional analysis of baseline data from the parent study was used to compare the factor structure of two models (one nested within the other) using confirmatory factor analysis. Although a comparison of the two models indicated that the addition of second-order factors for the content and context of nursing practice improved model fit, neither model provided optimal fit to the data. Additional model-generating research is needed to develop the DIS as a valid measure of decisional involvement for both the content and context of nursing practice. PMID:26074447

  18. Measured and predicted velocity and longitudinal dispersion at steady and unsteady flow, Colorado River, Glen Canyon Dam to lake mead

    USGS Publications Warehouse

    Graf, J.B.

    1995-01-01

    The effect of unsteadiness or dam releases on velocity and longitudinal dispersion of flow was evaluated by injecting a fluorescent dye into the Colorado River below Glen Canyon Dam and sampling for dye concentration at selected sites downstream. In Glen Canyon, average flow velocity through the study reach increased directly with discharge, but dispersion was greatest at the lowest of the three flows measured. In Grand Canyon, average flow velocity varied slightly from subreach to subreach at both steady and unsteady flow over the entire study reach. Also, longitudinal dispersion was not significantly different during steady and unsteady flow. Absence of tails on the curves shows that, at the measured flows, the eddies that are characteristic of the Grand Canyon reach do not trap water for a significant length of time. Data from the measurements were used to calibrate a one-dimensional now modeland a solute-transport model. The combined set of calibrated flow and solute-transport models was then used to predict velocity and dispersion at potential dam-release patterns.

  19. Longitudinal Effects of MRI-Measured Hepatic Steatosis on Biomarkers of Glucose Homeostasis and Hepatic Apoptosis in Obese Youth

    PubMed Central

    Kim, Grace; Giannini, Cosimo; Pierpont, Bridget; Feldstein, Ariel E.; Santoro, Nicola; Kursawe, Romy; Shaw, Melissa; Duran, Elvira; Goldberg, Rachel; Dziura, James; Caprio, Sonia

    2013-01-01

    OBJECTIVE We used fast-gradient magnetic resonance imaging (MRI) to determine the longitudinal associations between the hepatic fat content (HFF), glucose homeostasis, and a biomarker of hepatocellular apoptosis in obese youth. RESEARCH DESIGN AND METHODS Baseline and longitudinal liver and abdominal MRI were performed with an oral glucose tolerance test in 76 obese youth followed for an average of 1.9 years. Cytokeratin-18 (CK-18) was measured at baseline and follow-up as a biomarker of hepatic apoptosis. The relationship between baseline HFF and metabolic parameters and circulating levels of CK-18 at follow-up were assessed using a bivariate correlation. RESULTS At baseline, 38% had hepatic steatosis based on %HFF ≥5.5% with alterations in indices of insulin sensitivity and secretion. At follow-up, BMI increased in both groups and baseline %HFF correlated strongly with the follow-up %HFF (r = 0.81, P < 0.001). Over time, markers of insulin sensitivity and 2-h glucose improved significantly in the group without fatty liver, in contrast with the persistence of the insulin resistance and associated correlates in the fatty liver group. Baseline HFF correlated with 2-h glucose (r = 0.38, P = 0.001), whole-body insulin sensitivity (r = −0.405, P = 0.001), adiponectin (r = −0.44, P < 0.001), CK-18 levels, (r = 0.63, P < 0.001), and disposition index (r = −0.272, P = 0.021) at follow-up. In a multivariate analysis, we showed that baseline HFF is an independent predictor of 2-h glucose and whole-body insulin sensitivity. CONCLUSIONS In obese youth, the phenotype of MRI-measured hepatic steatosis is persistent. Baseline HFF strongly modulates longitudinally 2-h blood glucose, biomarkers of insulin resistance, and hepatocellular apoptosis. PMID:22933439

  20. Measurement of longitudinal spin asymmetries for weak boson production in polarized proton-proton collisions at RHIC.

    PubMed

    Adamczyk, L; Adkins, J K; Agakishiev, G; Aggarwal, M M; Ahammed, Z; Alekseev, I; Alford, J; Anson, C D; Aparin, A; Arkhipkin, D; Aschenauer, E C; Averichev, G S; Balewski, J; Banerjee, A; Beavis, D R; Bellwied, R; Bhasin, A; Bhati, A K; Bhattarai, P; Bichsel, H; Bielcik, J; Bielcikova, J; Bland, L C; Bordyuzhin, I G; Borowski, W; Bouchet, J; Brandin, A V; Brovko, S G; Bültmann, S; Bunzarov, I; Burton, T P; Butterworth, J; Caines, H; Calderón de la Barca Sánchez, M; Campbell, J M; Cebra, D; Cendejas, R; Cervantes, M C; Chaloupka, P; Chang, Z; Chattopadhyay, S; Chen, H F; Chen, J H; Chen, L; Cheng, J; Cherney, M; Chikanian, A; Christie, W; Chwastowski, J; Codrington, M J M; Contin, G; Cramer, J G; Crawford, H J; Cui, X; Das, S; Davila Leyva, A; De Silva, L C; Debbe, R R; Dedovich, T G; Deng, J; Derevschikov, A A; Derradi de Souza, R; Dhamija, S; di Ruzza, B; Didenko, L; Dilks, C; Ding, F; Djawotho, P; Dong, X; Drachenberg, J L; Draper, J E; Du, C M; Dunkelberger, L E; Dunlop, J C; Efimov, L G; Engelage, J; Engle, K S; Eppley, G; Eun, L; Evdokimov, O; Eyser, O; Fatemi, R; Fazio, S; Fedorisin, J; Filip, P; Finch, E; Fisyak, Y; Flores, C E; Gagliardi, C A; Gangadharan, D R; Garand, D; Geurts, F; Gibson, A; Girard, M; Gliske, S; Greiner, L; Grosnick, D; Gunarathne, D S; Guo, Y; Gupta, A; Gupta, S; Guryn, W; Haag, B; Hamed, A; Han, L-X; Haque, R; Harris, J W; Heppelmann, S; Hirsch, A; Hoffmann, G W; Hofman, D J; Horvat, S; Huang, B; Huang, H Z; Huang, X; Huck, P; Humanic, T J; Igo, G; Jacobs, W W; Jang, H; Judd, E G; Kabana, S; Kalinkin, D; Kang, K; Kauder, K; Ke, H W; Keane, D; Kechechyan, A; Kesich, A; Khan, Z H; Kikola, D P; Kisel, I; Kisiel, A; Koetke, D D; Kollegger, T; Konzer, J; Koralt, I; Kosarzewski, L K; Kotchenda, L; Kraishan, A F; Kravtsov, P; Krueger, K; Kulakov, I; Kumar, L; Kycia, R A; Lamont, M A C; Landgraf, J M; Landry, K D; Lauret, J; Lebedev, A; Lednicky, R; Lee, J H; LeVine, M J; Li, C; Li, W; Li, X; Li, X; Li, Y; Li, Z M; Lisa, M A; Liu, F; Ljubicic, T; Llope, W J; Lomnitz, M; Longacre, R S; Luo, X; Ma, G L; Ma, Y G; Madagodagettige Don, D M M D; Mahapatra, D P; Majka, R; Margetis, S; Markert, C; Masui, H; Matis, H S; McDonald, D; McShane, T S; Minaev, N G; Mioduszewski, S; Mohanty, B; Mondal, M M; Morozov, D A; Mustafa, M K; Nandi, B K; Nasim, Md; Nayak, T K; Nelson, J M; Nigmatkulov, G; Nogach, L V; Noh, S Y; Novak, J; Nurushev, S B; Odyniec, G; Ogawa, A; Oh, K; Ohlson, A; Okorokov, V; Oldag, E W; Olvitt, D L; Pachr, M; Page, B S; Pal, S K; Pan, Y X; Pandit, Y; Panebratsev, Y; Pawlak, T; Pawlik, B; Pei, H; Perkins, C; Peryt, W; Pile, P; Planinic, M; Pluta, J; Poljak, N; Poniatowska, K; Porter, J; Poskanzer, A M; Pruthi, N K; Przybycien, M; Pujahari, P R; Putschke, J; Qiu, H; Quintero, A; Ramachandran, S; Raniwala, R; Raniwala, S; Ray, R L; Riley, C K; Ritter, H G; Roberts, J B; Rogachevskiy, O V; Romero, J L; Ross, J F; Roy, A; Ruan, L; Rusnak, J; Rusnakova, O; Sahoo, N R; Sahu, P K; Sakrejda, I; Salur, S; Sandweiss, J; Sangaline, E; Sarkar, A; Schambach, J; Scharenberg, R P; Schmah, A M; Schmidke, W B; Schmitz, N; Seger, J; Seyboth, P; Shah, N; Shahaliev, E; Shanmuganathan, P V; Shao, M; Sharma, B; Shen, W Q; Shi, S S; Shou, Q Y; Sichtermann, E P; Singaraju, R N; Skoby, M J; Smirnov, D; Smirnov, N; Solanki, D; Sorensen, P; Spinka, H M; Srivastava, B; Stanislaus, T D S; Stevens, J R; Stock, R; Strikhanov, M; Stringfellow, B; Sumbera, M; Sun, X; Sun, X M; Sun, Y; Sun, Z; Surrow, B; Svirida, D N; Symons, T J M; Szelezniak, M A; Takahashi, J; Tang, A H; Tang, Z; Tarnowsky, T; Thomas, J H; Timmins, A R; Tlusty, D; Tokarev, M; Trentalange, S; Tribble, R E; Tribedy, P; Trzeciak, B A; Tsai, O D; Turnau, J; Ullrich, T; Underwood, D G; Van Buren, G; van Nieuwenhuizen, G; Vandenbroucke, M; Vanfossen, J A; Varma, R; Vasconcelos, G M S; Vasiliev, A N; Vertesi, R; Videbæk, F; Viyogi, Y P; Vokal, S; Vossen, A; Wada, M; Wang, F; Wang, G; Wang, H; Wang, J S; Wang, X L; Wang, Y; Wang, Y; Webb, G; Webb, J C; Westfall, G D; Wieman, H; Wissink, S W; Witt, R; Wu, Y F; Xiao, Z; Xie, W; Xin, K; Xu, H; Xu, J; Xu, N; Xu, Q H; Xu, Y; Xu, Z; Yan, W; Yang, C; Yang, Y; Yang, Y; Ye, Z; Yepes, P; Yi, L; Yip, K; Yoo, I-K; Yu, N; Zawisza, Y; Zbroszczyk, H; Zha, W; Zhang, J B; Zhang, J L; Zhang, S; Zhang, X P; Zhang, Y; Zhang, Z P; Zhao, F; Zhao, J; Zhong, C; Zhu, X; Zhu, Y H; Zoulkarneeva, Y; Zyzak, M

    2014-08-15

    We report measurements of single- and double-spin asymmetries for W^{±} and Z/γ^{*} boson production in longitudinally polarized p+p collisions at sqrt[s]=510  GeV by the STAR experiment at RHIC. The asymmetries for W^{±} were measured as a function of the decay lepton pseudorapidity, which provides a theoretically clean probe of the proton's polarized quark distributions at the scale of the W mass. The results are compared to theoretical predictions, constrained by polarized deep inelastic scattering measurements, and show a preference for a sizable, positive up antiquark polarization in the range 0.05

  1. Daily Associations Between Drinking and Sex Among College Students: A Longitudinal Measurement Burst Design

    PubMed Central

    Maggs, Jennifer L.; Lefkowitz, Eva S.

    2015-01-01

    Daily links between alcohol use and sexual behaviors were examined in a longitudinal study of college students. Hierarchical linear models predicted sexual behaviors by characteristics of persons (N=731; Level 3), semesters (N=4,345, Level 2), and days (N=56,372, Level 1). On a given day, consuming more drinks and binge drinking were associated with greater odds of kissing, touching, oral sex, and penetrative sex. Consistent with alcohol myopia and expectancy theories, associations between binge drinking and sexual behaviors were stronger for students not in romantic relationships, for students with stronger alcohol-sex expectancies, and for oral and penetrative sex. Findings suggest that within-day links between alcohol use and sexual behaviors are evident across college, with variations based on individual and relationship factors. PMID:26052189

  2. Longitudinal impedance of RHIC

    SciTech Connect

    Blaskiewicz, M.; Brennan, J. M.; Mernick, K.

    2015-05-03

    The longitudinal impedance of the two RHIC rings has been measured using the effect of potential well distortion on longitudinal Schottky measurements. For the blue RHIC ring Im(Z/n) = 1.5±0.2Ω. For the yellow ring Im(Z/n) = 5.4±1Ω.

  3. Rapid and Progressive Regional Brain Atrophy in CLN6 Batten Disease Affected Sheep Measured with Longitudinal Magnetic Resonance Imaging.

    PubMed

    Sawiak, Stephen J; Perumal, Sunthara Rajan; Rudiger, Skye R; Matthews, Loren; Mitchell, Nadia L; McLaughlan, Clive J; Bawden, C Simon; Palmer, David N; Kuchel, Timothy; Morton, A Jennifer

    2015-01-01

    Variant late-infantile Batten disease is a neuronal ceroid lipofuscinosis caused by mutations in CLN6. It is a recessive genetic lysosomal storage disease characterised by progressive neurodegeneration. It starts insidiously and leads to blindness, epilepsy and dementia in affected children. Sheep that are homozygous for a natural mutation in CLN6 have an ovine form of Batten disease Here, we used in vivo magnetic resonance imaging to track brain changes in 4 unaffected carriers and 6 affected Batten disease sheep. We scanned each sheep 4 times, between 17 and 22 months of age. Cortical atrophy in all sheep was pronounced at the baseline scan in all affected Batten disease sheep. Significant atrophy was also present in other brain regions (caudate, putamen and amygdala). Atrophy continued measurably in all of these regions during the study. Longitudinal MRI in sheep was sensitive enough to measure significant volume changes over the relatively short study period, even in the cortex, where nearly 40% of volume was already lost at the start of the study. Thus longitudinal MRI could be used to study the dynamics of progression of neurodegenerative changes in sheep models of Batten disease, as well as to assess therapeutic efficacy. PMID:26161747

  4. Rapid and Progressive Regional Brain Atrophy in CLN6 Batten Disease Affected Sheep Measured with Longitudinal Magnetic Resonance Imaging

    PubMed Central

    Sawiak, Stephen J.; Perumal, Sunthara Rajan; Rudiger, Skye R.; Matthews, Loren; Mitchell, Nadia L.; McLaughlan, Clive J.; Bawden, C. Simon; Palmer, David N.; Kuchel, Timothy; Morton, A. Jennifer

    2015-01-01

    Variant late-infantile Batten disease is a neuronal ceroid lipofuscinosis caused by mutations in CLN6. It is a recessive genetic lysosomal storage disease characterised by progressive neurodegeneration. It starts insidiously and leads to blindness, epilepsy and dementia in affected children. Sheep that are homozygous for a natural mutation in CLN6 have an ovine form of Batten disease Here, we used in vivo magnetic resonance imaging to track brain changes in 4 unaffected carriers and 6 affected Batten disease sheep. We scanned each sheep 4 times, between 17 and 22 months of age. Cortical atrophy in all sheep was pronounced at the baseline scan in all affected Batten disease sheep. Significant atrophy was also present in other brain regions (caudate, putamen and amygdala). Atrophy continued measurably in all of these regions during the study. Longitudinal MRI in sheep was sensitive enough to measure significant volume changes over the relatively short study period, even in the cortex, where nearly 40% of volume was already lost at the start of the study. Thus longitudinal MRI could be used to study the dynamics of progression of neurodegenerative changes in sheep models of Batten disease, as well as to assess therapeutic efficacy. PMID:26161747

  5. Insightful practice: a reliable measure for medical revalidation

    PubMed Central

    Guthrie, Bruce; Sullivan, Frank M; Mercer, Stewart W; Russell, Andrew; Bruce, David A

    2012-01-01

    Background Medical revalidation decisions need to be reliable if they are to reassure on the quality and safety of professional practice. This study tested an innovative method in which general practitioners (GPs) were assessed on their reflection and response to a set of externally specified feedback. Setting and participants 60 GPs and 12 GP appraisers in the Tayside region of Scotland, UK. Methods A feedback dataset was specified as (1) GP-specific data collected by GPs themselves (patient and colleague opinion; open book self-evaluated knowledge test; complaints) and (2) Externally collected practice-level data provided to GPs (clinical quality and prescribing safety). GPs' perceptions of whether the feedback covered UK General Medical Council specified attributes of a ‘good doctor’ were examined using a mapping exercise. GPs' professionalism was examined in terms of appraiser assessment of GPs' level of insightful practice, defined as: engagement with, insight into and appropriate action on feedback data. The reliability of assessment of insightful practice and subsequent recommendations on GPs' revalidation by face-to-face and anonymous assessors were investigated using Generalisability G-theory. Main outcome measures Coverage of General Medical Council attributes by specified feedback and reliability of assessor recommendations on doctors' suitability for revalidation. Results Face-to-face assessment proved unreliable. Anonymous global assessment by three appraisers of insightful practice was highly reliable (G=0.85), as were revalidation decisions using four anonymous assessors (G=0.83). Conclusions Unlike face-to-face appraisal, anonymous assessment of insightful practice offers a valid and reliable method to decide GP revalidation. Further validity studies are needed. PMID:22653078

  6. Predicting Progression of ABCA4-Associated Retinal Degenerations Based on Longitudinal Measurements of the Leading Disease Front

    PubMed Central

    Cideciyan, Artur V.; Swider, Malgorzata; Schwartz, Sharon B.; Stone, Edwin M.; Jacobson, Samuel G.

    2015-01-01

    Purpose To evaluate the progression of the earliest stage of disease in ABCA4-associated retinal degenerations (RDs). Methods Near-infrared excited reduced-illuminance autofluorescence imaging was acquired across the retina up to 80 degrees eccentricity in 44 patients with two ABCA4 alleles. The eccentricity of the leading disease front (LDF) corresponding to the earliest stage of disease was measured along the four meridians. A mathematical model describing the expansion of the LDF was developed based on 6 years of longitudinal follow-up. Results The extent of LDF along the superior, inferior, and temporal meridians showed a wide spectrum from 3.5 to 70 degrees. In patients with longitudinal data, the average centrifugal expansion rate was 2 degrees per year. The nasal extent of LDF between the fovea and ONH ranged from 4.3 to 16.5 degrees and expanded at 0.35 degrees per year. The extent of LDF beyond ONH ranged from 19 to 75 degrees and expanded on average at 2 degrees per year. A mathematical model fit well to the longitudinal data describing the expansion of the LDF. Conclusions The eccentricity of the LDF in ABCA4-RD shows a continuum from parafovea to far periphery along all four meridians consistent with a wide spectrum of severity observed clinically. The model of progression may provide a quantitative prediction of the LDF expansion based on the age and eccentricity of the LDF at a baseline visit, and thus contribute significantly to the enrollment of candidates appropriate for clinical trials planning specific interventions, efficacy outcomes, and durations. PMID:26377081

  7. Assessing Quality of Diabetes Care by Measuring Longitudinal Changes in Hemoglobin A1c in the Veterans Health Administration

    PubMed Central

    Thompson, Wes; Wang, Hongwei; Xie, Minge; Kolassa, John; Rajan, Mangala; Tseng, Chin-Lin; Crystal, Stephen; Zhang, Quanwu; Vardi, Yehuda; Pogach, Leonard; Safford, Monika M

    2005-01-01

    Context A1c levels are widely used to assess quality of diabetes care provided by health care systems. Currently, cross-sectional measures are commonly used for such assessments. Objective To study within-patient longitudinal changes in A1c levels at Veterans Health Administration (VHA) facilities as an alternative to cross-sectional measures of quality of diabetes care. Design Longitudinal study using institutional data on individual patient A1c level over time (October 1, 1998–September 30, 2000) with time variant and invariant covariates. Setting One hundred and twenty-five VHA facilities nationwide, October 1, 1998–September 30, 2000. Patients Diabetic veteran users with A1c measurement performed using National Glycosylated Hemoglobin Standardization Project certified A1c lab assay methods. Exposures Characteristics unlikely to reflect quality of care, but known to influence A1c levels, demographics, and baseline illness severity. Main Outcome Measure Monthly change in A1c for average patient cared for at each facility. Results The preponderance of facilities showed monthly declines in within-patient A1c over the study period (mean change of −0.0148 A1c units per month, range −0.074 to 0.042). Individual facilities varied in their monthly change, with 105 facilities showing monthly declines (70 significant at .05 level) and 20 showing monthly increases (5 significant at .05 level). Case-mix adjustment resulted in modest changes (mean change of −0.0131 case-mix adjusted A1c units per month, range −0.079 to 0.043). Facilities were ranked from worst to best, with attached 90 percent confidence intervals. Among the bottom 10 ranked facilities, four remained within the bottom decile with 90 percent confidence. Conclusions There is substantial variation in facility-level longitudinal changes in A1c levels. We propose that evaluation of change in A1c levels over time can be used as a new measure to reflect quality of care provided to populations of

  8. Single and double spin asymmetries for deeply virtual Compton scattering measured with CLAS and a longitudinally polarized proton target

    SciTech Connect

    Pisano, S.; Biselli, A.; Niccolai, S.; Seder, E.; Guidal, M.; Mirazita, M.; Adhikari, K. P.; Adikaram, D.; Amaryan, M. J.; Anderson, M. D.; Anefalos Pereira, S.; Avakian, H.; Ball, J.; Battaglieri, M.; Batourine, V.; Bedlinskiy, I.; Bosted, P.; Briscoe, B.; Brock, J.; Brooks, W. K.; Burkert, V. D.; Carlin, C.; Carman, D. S.; Celentano, A.; Chandavar, S.; Charles, G.; Colaneri, L.; Cole, P. L.; Compton, N.; Contalbrigo, M.; Cortes, O.; Crabb, D. G.; Crede, V.; D' Angelo, A.; De Vita, R.; De Sanctis, E.; Deur, A.; Djalali, C.; Dupre, R.; Egiyan, H.; El Alaoui, A.; El Fassi, L.; Elouadrhiri, L.; Eugenio, P.; Fedotov, G.; Fegan, S.; Fersch, R.; Filippi, A.; Fleming, J. A.; Fradi, A.; Garillon, B.; Garcon, M.; Ghandilyan, Y.; Gilfoyle, G. P.; Giovanetti, K. L.; Girod, F. X.; Goetz, J. T.; Gohn, W.; Golovatch, E.; Gothe, R. W.; Griffioen, K. A.; Guo, L.; Hafidi, K.; Hanretty, C.; Hattawy, M.; Hicks, K.; Holtrop, M.; Hughes, S. M.; Ilieva, Y.; Ireland, D. G.; Ishkhanov, B. S.; Jenkins, D.; Jiang, X.; Jo, H. S.; Joo, K.; Joosten, S.; Keith, C. D.; Keller, D.; Kim, A.; Kim, W.; Klein, F. J.; Kubarovsky, V.; Kuhn, S. E.; Lenisa, P.; Livingston, K.; Lu, H. Y.; MacCormick, M.; MacGregor, Ian J. D.; Mayer, M.; McKinnon, B.; Meekins, D. G.; Meyer, C. A.; Mokeev, V.; Montgomery, R. A.; Moody, C. I.; Munoz Camacho, C.; Nadel-Turonski, P.; Osipenko, M.; Ostrovidov, A. I.; Park, K.; Phelps, W.; Phillips, J. J.; Pogorelko, O.; Price, J. W.; Procureur, S.; Prok, Y.; Puckett, A. J. R.; Ripani, M.; Rizzo, A.; Rosner, G.; Rossi, P.; Roy, P.; Sabatie, F.; Salgado, C.; Schott, D.; Schumacher, R. A.; Skorodumina, I.; Smith, G. D.; Sober, D. I.; Sokhan, D.; Sparveris, N.; Stepanyan, S.; Stoler, P.; Strauch, S.; Sytnik, V.; Tian, Ye; Tkachenko, S.; Turisini, M.; Ungaro, M.; Voutier, E.; Walford, N. K.; Watts, D. P.; Wei, X.; Weinstein, L. B.; Wood, M. H.; Zachariou, N.; Zana, L.; Zhang, J.; Zhao, Z. W.; Zonta, I.

    2015-03-19

    Single-beam, single-target, and double-spin asymmetries for hard exclusive photon production on the proton e→p→e'p'γ are presented. The data were taken at Jefferson Lab using the CLAS detector and a longitudinally polarized 14NH3 target. The three asymmetries were measured in 165 4-dimensional kinematic bins, covering the widest kinematic range ever explored simultaneously for beam and target-polarization observables in the valence quark region. The kinematic dependences of the obtained asymmetries are discussed and compared to the predictions of models of Generalized Parton Distributions. As a result, the measurement of three DVCS spin observables at the same kinematic points allows a quasi-model-independent extraction of the imaginary parts of the H and H~ Compton Form Factors, which give insight into the electric and axial charge distributions of valence quarks in the proton.

  9. Practical Experience of Discharge Measurement in Flood Conditions with ADP

    NASA Astrophysics Data System (ADS)

    Vidmar, A.; Brilly, M.; Rusjan, S.

    2009-04-01

    Accurate discharge estimation is important for an efficient river basin management and especially for flood forecasting. The traditional way of estimating the discharge in hydrological practice is to measure the water stage and to convert the recorded water stage values into discharge by using the single-valued rating curve .Relationship between the stage and discharge values of the rating curve for the extreme events are usually extrapolated by using different mathematical methods and are not directly measured. Our practice shows that by using the Accoustic Doppler Profiler (ADP) instrument we can record the actual relation between the water stage and the flow velocity at the occurrence of flood waves very successfully. Measurement in flood conditions it is not easy task, because of high water surface velocity and large amounts of sediments in the water and floating objects on the surface like branches, bushes, trees, piles and others which can also easily damage ADP instrument. We made several measurements in such extreme events on the Sava River down to the nuclear power plant Kr\\vsko where we have install fixed cable way. During the several measurement with traditional "moving-boat" measurement technique a mowing bed phenomenon was clearly seen. Measuring flow accurately using ADP that uses the "moving-boat" technique, the system needs a reference against which to relate water velocities to. This reference is river bed and must not move. During flood events we detected difficulty finding a static bed surface to which to relate water velocities. This is caused by motion of the surface layer of bed material or also sediments suspended in the water near bed very densely. So these traditional »moving-boat« measurement techniques that we normally use completely fail. Using stationary measurement method to making individual velocity profile measurements, using an Acoustic Doppler Profiler (ADP), at certain time at fixed locations across the width of a stream gave

  10. Reference intervals, longitudinal analyses, and index of individuality of commonly measured laboratory variables in captive bald eagles (Haliaeetus leucocephalus).

    PubMed

    Jones, Michael P; Arheart, Kristopher L; Cray, Carolyn

    2014-06-01

    The objectives of this study were to determine reference intervals, perform longitudinal analyses, and determine the index of individuality (IoI) of 8 hematologic, and 13 biochemical and electrophoretic variables for a group of captive bald eagles (Haliaeetus leucocephalus). Reference intervals were determined from blood samples collected during annual wellness examinations for 41 eagles (23 male and 18 female) with ages ranging between 6 and 43 years (18.7 +/- 7.4, mean +/- SD) at the time of sample collection. Longitudinal analyses and IoI were determined for measured hematologic, biochemical, and protein electrophoretic variables, both individually and as a group, for a subset of 16 eagles (10 male and 6 female) during a 12-year period. This smaller group of eagles ranged in age between 2 and 20 years at the start of the study period, and between 14 and 32 years (21.9 +/- 5.0, mean +/- SD) at the end of the study period. Significant increases with age within the group of 16 eagles were observed only for red blood cells, percent heterophils, total protein, and beta-globulin protein fraction, while albumin:globulin decreased significantly with age. A low IoI (> or = 1.4) was determined for all hematologic and biochemical variables except gamma globulins, which had high IoI (< or = 0.6) for 3 individuals within the subset of 16. PMID:25115040

  11. Who are the young children for whom best practices in reading are ineffective? An experimental and longitudinal study.

    PubMed

    Al Otaiba, Stephanie; Fuchs, Douglas

    2006-01-01

    The primary purpose of this study was to identify student characteristics that reliably predict responsiveness and nonresponsiveness to generally effective early literacy interventions. Participants were 104 children, including 7 with special needs and Individualized Education Programs (IEPs), who were tested in kindergarten and first grade. Responsiveness/nonresponsiveness status was determined after 2 years during which children participated in best practice instruction (a) in kindergarten and first grade, (b) in kindergarten only, (c) in first grade only, or (d) in neither year. This facilitated the study of three groups. Always responsive students met responsiveness criteria in both years. Sometimes responsive students met the criteria in only one year. Nonresponsive students did not meet the criteria in either year. Multivariate analysis of variance and discriminant function analysis indicated that the three groups were reliably different from one another on measures of problem behavior, verbal memory, sentence imitation, syntactic awareness, vocabulary, naming speed, and segmentation. A combination of naming speed, vocabulary, sentence imitation, problem behavior, and amount of intervention correctly predicted 82.1% of nonresponsive students, 30.0% of sometimes responsive students, and 84.1% of always responsive students. Fifty students from kindergarten and first grade were tested again at the end of what should have been their third-grade year. All but 1 of the nonresponsive students who received intervention had been identified as requiring special education and had an IEP with reading goals. PMID:17004674

  12. Practice effects and longitudinal cognitive change in normal aging vs. incident mild cognitive impairment and dementia in the Mayo Clinic Study of Aging

    PubMed Central

    Machulda, Mary M.; Pankratz, V. Shane; Christianson, Teresa J.; Ivnik, Robert J.; Mielke, Michelle M.; Roberts, Rosebud O.; Knopman, David S.; Boeve, Bradley F.; Petersen, Ronald C.

    2013-01-01

    The objective of this study was to examine practice effects and longitudinal cognitive change in a population based cohort classified as clinically normal at their initial evaluation. We examined 1390 individuals with a median age of 78.1 years and re-evaluated them up to four times at approximate 15 month intervals, with an average follow-up time of five years. Of the 1390 participants, 947 (69%) individuals remained cognitively normal, 397 (29%) progressed to mild cognitive impairment (MCI), and 46 (3%) to dementia. The stable normal group showed an initial practice effect in all domains which was sustained in memory and visuospatial reasoning. There was only a slight decline in attention and language after visit 3. We combined individuals with incident MCI and dementia to form one group representing those who declined. The incident MCI/dementia group showed an unexpected practice effect in memory from baseline to visit 2, with a significant decline thereafter. This group did not demonstrate practice effects in any other domain and showed a downward trajectory in all domains at each evaluation. Modeling cognitive change in an epidemiologic sample may serve as a useful benchmark for evaluating cognitive change in future intervention studies. PMID:24041121

  13. Techniques for the measurement of body composition: a practical guide.

    PubMed

    Jebb, S A; Elia, M

    1993-11-01

    This paper discusses some of the practical aspects of both reference body composition methods (densitometry, isotope dilution methods, in vivo neutron activation analysis, dual energy X-ray absorptiometry, computerized tomographic scanning and magnetic resonance imaging) and bedsides or field techniques (weight and height indices, skinfold thicknesses impedance/resistance, near infra-red interactance and 24 hour creatinine excretion). Some techniques measure gross composition, in terms of fat and fat-free mass, or the components of fat-free tissue, such as water, mineral and protein, while other methods measure the mass of individual tissues, organs or body segments. The choice of a specific method for a particular study depends on various considerations including accuracy, precision, subject acceptability, convenience, cost, radiation exposure, and the need for observer training. The relative advantages and disadvantages of each method are discussed with these considerations in mind. PMID:8281219

  14. Design and RF measurements of an X-band accelerating structure for linearizing the longitudinal emittance at SPARC

    NASA Astrophysics Data System (ADS)

    Alesini, D.; Falone, A.; Migliorati, M.; Mostacci, A.; Palpini, F.; Palumbo, L.; Spataro, B.

    2005-12-01

    The paper presents the design of an X-band accelerating section for linearizing the longitudinal phase space in the Frascati Linac Coherent Light Source (SPARC). The nine cells structure, operating on the π standing wave mode, is fed by a central coupler and has been designed to obtain a 42 MV/m accelerating gradient. The two-dimensional (2D) profile has been obtained using the electromagnetic codes Superfish and Oscar-2D while the coupler has been designed using HFSS. Bead-pull measurements made on a copper prototype have been performed and the results are illustrated and compared with the numerical predictions. Mechanical details of the realized prototype and RF properties of the structure as a function of the assembly characteristics are also discussed.

  15. Measurement of parity-violating spin asymmetries in W± production at midrapidity in longitudinally polarized p +p collisions

    NASA Astrophysics Data System (ADS)

    Adare, A.; Aidala, C.; Ajitanand, N. N.; Akiba, Y.; Akimoto, R.; Alexander, J.; Alfred, M.; Aoki, K.; Apadula, N.; Aramaki, Y.; Asano, H.; Aschenauer, E. C.; Atomssa, E. T.; Awes, T. C.; Azmoun, B.; Babintsev, V.; Bai, M.; Bai, X.; Bandara, N. S.; Bannier, B.; Barish, K. N.; Bassalleck, B.; Bathe, S.; Baublis, V.; Baumann, C.; Baumgart, S.; Bazilevsky, A.; Beaumier, M.; Beckman, S.; Belmont, R.; Berdnikov, A.; Berdnikov, Y.; Black, D.; Blau, D. S.; Bok, J. S.; Boyle, K.; Brooks, M. L.; Bryslawskyj, J.; Buesching, H.; Bumazhnov, V.; Butsyk, S.; Campbell, S.; Chen, C.-H.; Chi, C. Y.; Chiu, M.; Choi, I. J.; Choi, J. B.; Choi, S.; Choudhury, R. K.; Christiansen, P.; Chujo, T.; Chvala, O.; Cianciolo, V.; Citron, Z.; Cole, B. A.; Connors, M.; Cronin, N.; Crossette, N.; Csanád, M.; Csörgő, T.; Dairaku, S.; Danley, T. W.; Datta, A.; Daugherity, M. S.; David, G.; Deblasio, K.; Dehmelt, K.; Denisov, A.; Deshpande, A.; Desmond, E. J.; Dietzsch, O.; Ding, L.; Dion, A.; Diss, P. B.; Do, J. H.; Donadelli, M.; D'Orazio, L.; Drapier, O.; Drees, A.; Drees, K. A.; Durham, J. M.; Durum, A.; Edwards, S.; Efremenko, Y. V.; Engelmore, T.; Enokizono, A.; En'yo, H.; Esumi, S.; Eyser, K. O.; Fadem, B.; Feege, N.; Fields, D. E.; Finger, M.; Finger, M.; Fleuret, F.; Fokin, S. L.; Frantz, J. E.; Franz, A.; Frawley, A. D.; Fukao, Y.; Fusayasu, T.; Gainey, K.; Gal, C.; Gallus, P.; Garg, P.; Garishvili, A.; Garishvili, I.; Ge, H.; Giordano, F.; Glenn, A.; Gong, X.; Gonin, M.; Goto, Y.; Granier de Cassagnac, R.; Grau, N.; Greene, S. V.; Grosse Perdekamp, M.; Gu, Y.; Gunji, T.; Guragain, H.; Hachiya, T.; Haggerty, J. S.; Hahn, K. I.; Hamagaki, H.; Hamilton, H. F.; Han, S. Y.; Hanks, J.; Hasegawa, S.; Haseler, T. O. S.; Hashimoto, K.; Hayano, R.; Hayashi, S.; He, X.; Hemmick, T. K.; Hester, T.; Hill, J. C.; Hollis, R. S.; Homma, K.; Hong, B.; Horaguchi, T.; Hoshino, T.; Hotvedt, N.; Huang, J.; Huang, S.; Ichihara, T.; Iinuma, H.; Ikeda, Y.; Imai, K.; Imazu, Y.; Imrek, J.; Inaba, M.; Iordanova, A.; Isenhower, D.; Isinhue, A.; Ivanishchev, D.; Jacak, B. V.; Javani, M.; Jeon, S. J.; Jezghani, M.; Jia, J.; Jiang, X.; Johnson, B. M.; Joo, E.; Joo, K. S.; Jouan, D.; Jumper, D. S.; Kamin, J.; Kanda, S.; Kang, B. H.; Kang, J. H.; Kang, J. S.; Kapustinsky, J.; Karatsu, K.; Kawall, D.; Kazantsev, A. V.; Kempel, T.; Key, J. A.; Khachatryan, V.; Khandai, P. K.; Khanzadeev, A.; Kihara, K.; Kijima, K. M.; Kim, B. I.; Kim, C.; Kim, D. H.; Kim, D. J.; Kim, E.-J.; Kim, G. W.; Kim, H.-J.; Kim, M.; Kim, Y.-J.; Kim, Y. K.; Kimelman, B.; Kinney, E.; Kistenev, E.; Kitamura, R.; Klatsky, J.; Kleinjan, D.; Kline, P.; Koblesky, T.; Kofarago, M.; Komkov, B.; Koster, J.; Kotchetkov, D.; Kotov, D.; Krizek, F.; Kurita, K.; Kurosawa, M.; Kwon, Y.; Kyle, G. S.; Lacey, R.; Lai, Y. S.; Lajoie, J. G.; Lebedev, A.; Lee, D. M.; Lee, G. H.; Lee, J.; Lee, K. B.; Lee, K. S.; Lee, S.; Lee, S. H.; Lee, S. R.; Leitch, M. J.; Leite, M. A. L.; Leitgab, M.; Lewis, B.; Li, X.; Lim, S. H.; Linden Levy, L. A.; Liu, M. X.; Lynch, D.; Maguire, C. F.; Makdisi, Y. I.; Makek, M.; Manion, A.; Manko, V. I.; Mannel, E.; Maruyama, T.; McCumber, M.; McGaughey, P. L.; McGlinchey, D.; McKinney, C.; Meles, A.; Mendoza, M.; Meredith, B.; Miake, Y.; Mibe, T.; Midori, J.; Mignerey, A. C.; Miller, A. J.; Milov, A.; Mishra, D. K.; Mitchell, J. T.; Miyasaka, S.; Mizuno, S.; Mohanty, A. K.; Mohapatra, S.; Montuenga, P.; Moon, H. J.; Moon, T.; Morrison, D. P.; Moskowitz, M.; Moukhanova, T. V.; Murakami, T.; Murata, J.; Mwai, A.; Nagae, T.; Nagamiya, S.; Nagashima, K.; Nagle, J. L.; Nagy, M. I.; Nakagawa, I.; Nakagomi, H.; Nakamiya, Y.; Nakamura, K. R.; Nakamura, T.; Nakano, K.; Nattrass, C.; Netrakanti, P. K.; Nihashi, M.; Niida, T.; Nishimura, S.; Nouicer, R.; Novák, T.; Novitzky, N.; Nukariya, A.; Nyanin, A. S.; Obayashi, H.; O'Brien, E.; Ogilvie, C. A.; Oide, H.; Okada, K.; Orjuela Koop, J. D.; Osborn, J. D.; Oskarsson, A.; Ozaki, H.; Ozawa, K.; Pak, R.; Pantuev, V.; Papavassiliou, V.; Park, I. H.; Park, J. S.; Park, S.; Park, S. K.; Pate, S. F.; Patel, L.; Patel, M.; Pei, H.; Peng, J.-C.; Perepelitsa, D. V.; Perera, G. D. N.; Peressounko, D. Yu.; Perry, J.; Petti, R.; Pinkenburg, C.; Pinson, R.; Pisani, R. P.; Purschke, M. L.; Qu, H.; Rak, J.; Ramson, B. J.; Ravinovich, I.; Read, K. F.; Reynolds, D.; Riabov, V.; Riabov, Y.; Richardson, E.; Rinn, T.; Riveli, N.; Roach, D.; Roche, G.; Rolnick, S. D.; Rosati, M.; Rowan, Z.; Rubin, J. G.; Ryu, M. S.; Sahlmueller, B.; Saito, N.; Sakaguchi, T.; Sako, H.; Samsonov, V.; Sarsour, M.; Sato, S.; Sawada, S.; Schaefer, B.; Schmoll, B. K.; Sedgwick, K.; Seele, J.; Seidl, R.; Sekiguchi, Y.; Sen, A.; Seto, R.; Sett, P.; Sexton, A.; Sharma, D.; Shaver, A.; Shein, I.; Shibata, T.-A.; Shigaki, K.; Shimomura, M.; Shoji, K.; Shukla, P.; Sickles, A.; Silva, C. L.; Silvermyr, D.; Sim, K. S.; Singh, B. K.; Singh, C. P.; Singh, V.; Skolnik, M.; Slunečka, M.; Snowball, M.; Solano, S.; Soltz, R. A.; Sondheim, W. E.; Sorensen, S. P.; Sourikova, I. V.; Stankus, P. W.; Steinberg, P.; Stenlund, E.; Stepanov, M.; Ster, A.; Stoll, S. P.; Stone, M. R.; Sugitate, T.; Sukhanov, A.; Sumita, T.; Sun, J.; Sziklai, J.; Takagui, E. M.; Takahara, A.; Taketani, A.; Tanaka, Y.; Taneja, S.; Tanida, K.; Tannenbaum, M. J.; Tarafdar, S.; Taranenko, A.; Tennant, E.; Tieulent, R.; Timilsina, A.; Todoroki, T.; Tomášek, M.; Torii, H.; Towell, C. L.; Towell, M.; Towell, R.; Towell, R. S.; Tserruya, I.; Tsuchimoto, Y.; Vale, C.; van Hecke, H. W.; Vargyas, M.; Vazquez-Zambrano, E.; Veicht, A.; Velkovska, J.; Vértesi, R.; Virius, M.; Voas, B.; Vrba, V.; Vznuzdaev, E.; Wang, X. R.; Watanabe, D.; Watanabe, K.; Watanabe, Y.; Watanabe, Y. S.; Wei, F.; Whitaker, S.; White, A. S.; White, S. N.; Winter, D.; Wolin, S.; Woody, C. L.; Wysocki, M.; Xia, B.; Xue, L.; Yalcin, S.; Yamaguchi, Y. L.; Yanovich, A.; Ying, J.; Yokkaichi, S.; Yoo, J. H.; Yoon, I.; You, Z.; Younus, I.; Yu, H.; Yushmanov, I. E.; Zajc, W. A.; Zelenski, A.; Zhou, S.; Zou, L.; Phenix Collaboration

    2016-03-01

    We present midrapidity measurements from the PHENIX experiment of large parity-violating single-spin asymmetries of high transverse momentum electrons and positrons from W±/Z decays, produced in longitudinally polarized p +p collisions at center of mass energies of √{s }=500 and 510 GeV. These asymmetries allow direct access to the antiquark polarized parton distribution functions due to the parity-violating nature of the W -boson coupling to quarks and antiquarks. The results presented are based on data collected in 2011, 2012, and 2013 with an integrated luminosity of 240 pb-1 , which exceeds previous PHENIX published results by a factor of more than 27. These high Q2 data probe the parton structure of the proton at W mass scale and provide an important addition to our understanding of the antiquark parton helicity distribution functions at an intermediate Bjorken x value of roughly MW/√{s }=0.16 .

  16. Factor Structure and Measurement Invariance of a 10-Item Decisional Balance Scale: Longitudinal and Subgroup Examination within an Adult Diabetic Sample

    ERIC Educational Resources Information Center

    Pickering, Michael A.; Plotnikoff, Ronald C.

    2009-01-01

    This study explores the longitudinal and subgroup measurement properties of a 10-item, physical activity decisional balance scale, previously published by Plotnikoff, Blanchard, Hotz, and Rhodes (2001), within a diabetic sample of Canadian adults. Results indicated that a three-factor measurement model consistently improved model fit compared to…

  17. Codifference as a practical tool to measure interdependence

    NASA Astrophysics Data System (ADS)

    Wyłomańska, Agnieszka; Chechkin, Aleksei; Gajda, Janusz; Sokolov, Igor M.

    2015-03-01

    Correlation and spectral analysis represent the standard tools to study interdependence in statistical data. However, for the stochastic processes with heavy-tailed distributions such that the variance diverges, these tools are inadequate. The heavy-tailed processes are ubiquitous in nature and finance. We here discuss codifference as a convenient measure to study statistical interdependence, and we aim to give a short introductory review of its properties. By taking different known stochastic processes as generic examples, we present explicit formulas for their codifferences. We show that for the Gaussian processes codifference is equivalent to covariance. For processes with finite variance these two measures behave similarly with time. For the processes with infinite variance the covariance does not exist, however, the codifference is relevant. We demonstrate the practical importance of the codifference by extracting this function from simulated as well as real data taken from turbulent plasma of fusion device and financial market. We conclude that the codifference serves as a convenient practical tool to study interdependence for stochastic processes with both infinite and finite variances as well.

  18. The Role of Sleep Disturbances in the Longitudinal Relationship Between Psychosocial Working Conditions, Measured by Work Demands and Support, and Depression

    PubMed Central

    Magnusson Hanson, Linda L.; Chungkham, Holendro Singh; Åkerstedt, Torbjörn; Westerlund, Hugo

    2014-01-01

    Study Objectives: Because work demands and lack of social support seem to be prospectively linked to sleep problems, and sleep problems are linked to depression, sleep problems may play a role in the relationship between these work characteristics and depressive symptoms. In order to shed more light on this relationship, the current study investigated whether disturbed sleep is a mediator in the longitudinal relationships between work demands, social support, and depression. Design: Longitudinal cohort study with repeated survey measures on four occasions. Setting: Swedish workforce. Participants: 2,017 working participants from the Swedish Longitudinal Occupational Survey of Health in 2006, 2008, 2010, and 2012. Measurements and results: Work demands (four items) and social support (six items) were assessed with the Demand Control Questionnaire, disturbed sleep (four items) with the Karolinska Sleep Questionnaire, and depressive symptoms with a brief subscale (six items) from the Symptom Checklist. Autoregressive longitudinal mediation models using structural equation modeling were tested. The work characteristics, and disturbed sleep, were found to be separately associated with depressive symptoms in subsequent waves. However, only demands were found to be longitudinally related to subsequent disturbed sleep. The longitudinal autoregressive models supported a weak mediating role of disturbed sleep in the relationship between demands and depressive symptoms (standardized beta 0.008, P < 0.001), but not between support and depressive symptoms. Conclusions: These results indicate that higher demands at work might cause an increase in depressive symptoms, in part, by increasing disturbed sleep, although the mediated effect was relatively small compared to the total effect. Citation: Magnusson Hanson LL, Chungkham HS, Åkerstedt T, Westerlund H. The role of sleep disturbances in the longitudinal relationship between psychosocial working conditions, measured by work

  19. Establishing Measurement Equivalence and Invariance in Longitudinal Data With Item Response Theory

    ERIC Educational Resources Information Center

    Meade, Adam W.; Lautenschlager, Gary J.; Hecht, Janet E.

    2005-01-01

    If measurement invariance does not hold over 2 or more measurement occasions, differences in observed scores are not directly interpretable. Golembiewski, Billingsley, and Yeager (1976) identified 2 types of psychometric differences over time as beta change and gamma change. Gamma change is a fundamental change in thinking about the nature of a…

  20. A Measure for the Reliability of a Rating Scale Based on Longitudinal Clinical Trial Data

    ERIC Educational Resources Information Center

    Laenen, Annouschka; Alonso, Ariel; Molenberghs, Geert

    2007-01-01

    A new measure for reliability of a rating scale is introduced, based on the classical definition of reliability, as the ratio of the true score variance and the total variance. Clinical trial data can be employed to estimate the reliability of the scale in use, whenever repeated measurements are taken. The reliability is estimated from the…

  1. Fiber Longitudinal Measurements for Predicting White Speck Contents of Dyed Cotton Fabrics

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Fiber Image Analysis System (FIAS) was developed to provide an automatic method for measuring cotton maturity from fiber snippets or cross-sections . An uncombed cotton bundle is chopped and sprayed on a microscopic slide. The snippets are imaged sequentially on an microscope and measured with custo...

  2. The Impact of Social Media on Dissemination and Implementation of Clinical Practice Guidelines: A Longitudinal Observational Study

    PubMed Central

    Gronseth, Gary; Dubinsky, Richard; Penfold-Murray, Rebecca; Cox, Julie; Bever Jr, Christopher; Martins, Yolanda; Rheaume, Carol; Shouse, Denise; Getchius, Thomas SD

    2015-01-01

    Background Evidence-based clinical practice guidelines (CPGs) are statements that provide recommendations to optimize patient care for a specific clinical problem or question. Merely reading a guideline rarely leads to implementation of recommendations. The American Academy of Neurology (AAN) has a formal process of guideline development and dissemination. The last few years have seen a burgeoning of social media such as Facebook, Twitter, and LinkedIn, and newer methods of dissemination such as podcasts and webinars. The role of these media in guideline dissemination has not been studied. Systematic evaluation of dissemination methods and comparison of the effectiveness of newer methods with traditional methods is not available. It is also not known whether specific dissemination methods may be more effectively targeted to specific audiences. Objective Our aim was to (1) develop an innovative dissemination strategy by adding social media-based dissemination methods to traditional methods for the AAN clinical practice guidelines “Complementary and alternative medicine in multiple sclerosis” (“CAM in MS”) and (2) evaluate whether the addition of social media outreach improves awareness of the CPG and knowledge of CPG recommendations, and affects implementation of those recommendations. Methods Outcomes were measured by four surveys in each of the two target populations: patients and physicians/clinicians (“physicians”). The primary outcome was the difference in participants’ intent to discuss use of complementary and alternative medicine (CAM) with their physicians or patients, respectively, after novel dissemination, as compared with that after traditional dissemination. Secondary outcomes were changes in awareness of the CPG, knowledge of CPG content, and behavior regarding CAM use in multiple sclerosis (MS). Results Response rates were 25.08% (622/2480) for physicians and 43.5% (348/800) for patients. Awareness of the CPG increased after traditional

  3. Variability in baseline laboratory measurements of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).

    PubMed

    Ladwig, R; Vigo, A; Fedeli, L M G; Chambless, L E; Bensenor, I; Schmidt, M I; Vidigal, P G; Castilhos, C D; Duncan, B B

    2016-01-01

    Multi-center epidemiological studies must ascertain that their measurements are accurate and reliable. For laboratory measurements, reliability can be assessed through investigation of reproducibility of measurements in the same individual. In this paper, we present results from the quality control analysis of the baseline laboratory measurements from the ELSA-Brasil study. The study enrolled 15,105 civil servants at 6 research centers in 3 regions of Brazil between 2008-2010, with multiple biochemical analytes being measured at a central laboratory. Quality control was ascertained through standard laboratory evaluation of intra- and inter-assay variability and test-retest analysis in a subset of randomly chosen participants. An additional sample of urine or blood was collected from these participants, and these samples were handled in the same manner as the original ones, locally and at the central laboratory. Reliability was assessed with the intraclass correlation coefficient (ICC), estimated through a random effects model. Coefficients of variation (CV) and Bland-Altman plots were additionally used to assess measurement variability. Laboratory intra and inter-assay CVs varied from 0.86% to 7.77%. From test-retest analyses, the ICCs were high for the majority of the analytes. Notably lower ICCs were observed for serum sodium (ICC=0.50; 95%CI=0.31-0.65) and serum potassium (ICC=0.73; 95%CI=0.60-0.83), due to the small biological range of these analytes. The CVs ranged from 1 to 14%. The Bland-Altman plots confirmed these results. The quality control analyses showed that the collection, processing and measurement protocols utilized in the ELSA-Brasil produced reliable biochemical measurements. PMID:27533768

  4. Variability in baseline laboratory measurements of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)

    PubMed Central

    Ladwig, R.; Vigo, A.; Fedeli, L.M.G.; Chambless, L.E.; Bensenor, I.; Schmidt, M.I.; Vidigal, P.G.; Castilhos, C.D.; Duncan, B.B.

    2016-01-01

    Multi-center epidemiological studies must ascertain that their measurements are accurate and reliable. For laboratory measurements, reliability can be assessed through investigation of reproducibility of measurements in the same individual. In this paper, we present results from the quality control analysis of the baseline laboratory measurements from the ELSA-Brasil study. The study enrolled 15,105 civil servants at 6 research centers in 3 regions of Brazil between 2008–2010, with multiple biochemical analytes being measured at a central laboratory. Quality control was ascertained through standard laboratory evaluation of intra- and inter-assay variability and test-retest analysis in a subset of randomly chosen participants. An additional sample of urine or blood was collected from these participants, and these samples were handled in the same manner as the original ones, locally and at the central laboratory. Reliability was assessed with the intraclass correlation coefficient (ICC), estimated through a random effects model. Coefficients of variation (CV) and Bland-Altman plots were additionally used to assess measurement variability. Laboratory intra and inter-assay CVs varied from 0.86% to 7.77%. From test-retest analyses, the ICCs were high for the majority of the analytes. Notably lower ICCs were observed for serum sodium (ICC=0.50; 95%CI=0.31–0.65) and serum potassium (ICC=0.73; 95%CI=0.60–0.83), due to the small biological range of these analytes. The CVs ranged from 1 to 14%. The Bland-Altman plots confirmed these results. The quality control analyses showed that the collection, processing and measurement protocols utilized in the ELSA-Brasil produced reliable biochemical measurements. PMID:27533768

  5. Longitudinal Association of Preference-Weighted Health-Related Quality of Life Measures and Substance Use Disorder Outcomes

    PubMed Central

    Pyne, Jeffrey M.; Tripathi, Shanti; French, Michael; McCollister, Kathryn; Rapp, Richard C.; Booth, Brenda M.

    2010-01-01

    Aim Examine the construct validity of generic preference-weighted health-related quality of life measures in a sample of patients with a substance use disorder (SUD). Design Longitudinal (baseline and six-month follow-up) data from a research study that evaluated interventions to improve linkage and engagement with SUD treatment. Setting A central intake unit that referred patients to seven SUD treatment centers in a Midwestern US metropolitan area. Participants 495 persons with a SUD. Measurements Participants completed two preference-weighted measures: self-administered Quality of Well-Being scale (QWB-SA) and standard gamble weighted Medical Outcomes Study SF-12 (SF-6D). They were also administered two clinical assessments: all seven domains of the Addiction Severity Index (ASI) and a symptom checklist based on the DSM-IV. Construct validity was determined via the relationships between disease-specific SUD and generic measures. Findings In unadjusted analyses, the QWB-SA and SF-6D change scores were significantly correlated with six ASI subscale change scores, but not with employment status. In adjusted repeated measures analyses, 3/7 ASI subscale scores were significant predictors of QWB-SA and 5/7 ASI subscale scores were significant predictors of SF-6D. Abstinence and problematic use at follow-up were significant predictors of QWB-SA and SF-6D. Effect sizes ranged from 0.352 to 0.400 for abstinence and −0.484 to −0.585 for problematic use. Conclusions Generic preference-weighted health-related quality of life measures show moderate to good associations with substance-use specific measures and in certain circumstances can be used in their stead. This study provides further support for the use of the QWB-SA and SF-6D in clinical and economic evaluations of SUD interventions. PMID:21205046

  6. Increasing the sensitivity of NMR diffusion measurements by paramagnetic longitudinal relaxation enhancement, with application to ribosome–nascent chain complexes

    PubMed Central

    Cassaignau, Anaïs M. E.; Cabrita, Lisa D.

    2016-01-01

    The translational diffusion of macromolecules can be examined non-invasively by stimulated echo (STE) NMR experiments to accurately determine their molecular sizes. These measurements can be important probes of intermolecular interactions and protein folding and unfolding, and are crucial in monitoring the integrity of large macromolecular assemblies such as ribosome–nascent chain complexes (RNCs). However, NMR studies of these complexes can be severely constrained by their slow tumbling, low solubility (with maximum concentrations of up to 10 μM), and short lifetimes resulting in weak signal, and therefore continuing improvements in experimental sensitivity are essential. Here we explore the use of the paramagnetic longitudinal relaxation enhancement (PLRE) agent NiDO2A on the sensitivity of 15N XSTE and SORDID heteronuclear STE experiments, which can be used to monitor the integrity of these unstable complexes. We exploit the dependence of the PLRE effect on the gyromagnetic ratio and electronic relaxation time to accelerate recovery of 1H magnetization without adversely affecting storage on Nz during diffusion delays or introducing significant transverse relaxation line broadening. By applying the longitudinal relaxation-optimized SORDID pulse sequence together with NiDO2A to 70S Escherichia coli ribosomes and RNCs, NMR diffusion sensitivity enhancements of up to 4.5-fold relative to XSTE are achieved, alongside ~1.9-fold improvements in two-dimensional NMR sensitivity, without compromising the sample integrity. We anticipate these results will significantly advance the use of NMR to probe dynamic regions of ribosomes and other large, unstable macromolecular assemblies. PMID:26253948

  7. Longitudinal Transient Elastography Measurements Used in Follow-up for Patients with Cystic Fibrosis.

    PubMed

    Van Biervliet, Stephanie; Verdievel, Hugo; Vande Velde, Saskia; De Bruyne, Ruth; De Looze, Danny; Verhelst, Xavier; Geerts, Anja; Robberecht, Eddy; Van Vlierberghe, Hans

    2016-04-01

    Cystic fibrosis-related liver disease (CFLD) is diagnosed using a combination of criteria. Transient elastography (TE), an ultrasonographic method to evaluate liver stiffness, can differentiate patients with and without liver disease. This retrospective study (2007-2013) aimed to detect developing CFLD using consequent TE measurements. All cystic fibrosis patients with TE measurements between 2007 and 2013 (n = 150, median age 17 (9-24) y) were included, of which 118 had a median of three (range, 2-4) measurements with an interval of 1 (1-2) y. Twenty (14%) had CFLD at the first TE measurement; five (3%) developed CFLD during follow-up. The median TE value in CFLD was 14 kPa (8.7-32.2) compared with 5.3 (4.9-5.7) in cystic fibrosis patients without liver disease (CFnoLD; p = 0.0001). In CFnoLD, TE was correlated with age (p = 0.031). A TE result >6.8 kPa had a sensitivity of 91.5% and a specificity of 91.7% in predicting CFLD, according to the receiver operating characteristics analysis. It also has a positive predictive value of 88.6% and a negative predictive value of 86.9%, increasing to 91.7% and 98%, respectively, in patients at risk (<14 y) for developing CFLD. Patients with developing CFLD had progressively increasing consecutive TE measurements. PMID:26806442

  8. Measurement of impulsivity: construct coherence, longitudinal stability, and relationship with externalizing problems in middle childhood and adolescence.

    PubMed

    Olson, S L; Schilling, E M; Bates, J E

    1999-04-01

    This study focused on the assessment of impulsivity in nonreferred school-aged children. Children had been participants since infancy in the Bloomington Longitudinal Study. Individual differences in impulsivity were assessed in the laboratory when children were 6 (44 boys, 36 girls) and 8 (50 boys, 39 girls) years of age. Impulsivity constructs derived from these assessments were related to parent and teacher ratings of externalizing problems across the school-age period (ages 7-10) and to parent and self-ratings of these outcomes across adolescence (ages 14-17). Consistent with prior research, individual measures of impulsivity factor-analyzed into subdimensions reflecting children's executive control capabilities, delay of gratification, and ability or willingness to sustain attention and compliance during work tasks. Children's performance on the main interactive task index, inhibitory control, showed a signficant level of stability between ages 6 and 8. During the school-age years, children who performed impulsively on the laboratory measures were perceived by mothers and by teachers as more impulsive, inattentive, and overactive than others, affirming the external validity of the impulsivity constructs. Finally, impulsive behavior in the laboratory at ages 6 and 8 predicted maternal and self-ratings of externalizing problem behavior across adolescence, supporting the long-term predictive value of the laboratory-derived impulsivity measures. PMID:10400061

  9. Why use automated office blood pressure measurements in clinical practice?

    PubMed

    Andreadis, Emmanuel A; Angelopoulos, Epameinondas T; Agaliotis, Gerasimos D; Tsakanikas, Athanasios P; Mousoulis, George P

    2011-09-01

    Automated office blood pressure (AOBP) measurement with the patient resting alone in a quiet examining room can eliminate the white-coat effect associated with conventional readings taken by manual sphygmomanometer. The key to reducing the white-coat response appears to be multiple blood pressure (BP) readings taken in a non-observer office setting, thus eliminating any interaction that could provoke an office-induced increase in BP. Furthermore, AOBP readings have shown a higher correlation with the mean awake ambulatory BP compared with BP readings recorded in routine clinical practice. Although there is a paucity of studies connecting AOBP with organ damage, AOBP values were recently found to be equally associated with left ventricular mass index as those of ambulatory BP. This concludes that in contrast to routine manual office BP, AOBP readings compare favourably with 24-hour ambulatory BP measurements in the appraisal of cardiac remodelling and, as such, could be complementary to ambulatory readings in a way similar to home BP measurements. PMID:21950780

  10. Frailty measurement in research and clinical practice: A review.

    PubMed

    Dent, Elsa; Kowal, Paul; Hoogendijk, Emiel O

    2016-06-01

    One of the leading causes of morbidity and premature mortality in older people is frailty. Frailty occurs when multiple physiological systems decline, to the extent that an individual's cellular repair mechanisms cannot maintain system homeostasis. This review gives an overview of the definitions and measurement of frailty in research and clinical practice, including: Fried's frailty phenotype; Rockwood and Mitnitski's Frailty Index (FI); the Study of Osteoporotic Fractures (SOF) Index; Edmonton Frailty Scale (EFS); the Fatigue, Resistance, Ambulation, Illness and Loss of weight (FRAIL) Index; Clinical Frailty Scale (CFS); the Multidimensional Prognostic Index (MPI); Tilburg Frailty Indicator (TFI); PRISMA-7; Groningen Frailty Indicator (GFI), Sherbrooke Postal Questionnaire (SPQ); the Gérontopôle Frailty Screening Tool (GFST) and the Kihon Checklist (KCL), among others. We summarise the main strengths and limitations of existing frailty measurements, and examine how well these measurements operationalise frailty according to Clegg's guidelines for frailty classification - that is: their accuracy in identifying frailty; their basis on biological causative theory; and their ability to reliably predict patient outcomes and response to potential therapies. PMID:27039014

  11. The mathematical tale of two teachers: A longitudinal study relating mathematics instructional practices to level of intellectual development

    NASA Astrophysics Data System (ADS)

    Cady, Joann; Meier, Sherry L.; Lubinski, Cheryl A.

    2006-05-01

    In this article the development of two teachers as they make the transition from pre-service teachers to experienced teachers is examined. While these teachers participated in the same mathematics methods course and similar collaborative environments in their practicum experiences, their mathematics classroom instructional practices revealed stark differences by the time they were experienced teachers. In an effort to investigate these differences, the teachers' beliefs were explored in relation to those promoted in their pre-service course and in relation to their implementation of current mathematics education reform practices.

  12. Measuring Knowledge Integration Learning of Energy Topics: A Two-Year Longitudinal Study

    ERIC Educational Resources Information Center

    Liu, Ou Lydia; Ryoo, Kihyun; Linn, Marcia C.; Sato, Elissa; Svihla, Vanessa

    2015-01-01

    Although researchers call for inquiry learning in science, science assessments rarely capture the impact of inquiry instruction. This paper reports on the development and validation of assessments designed to measure middle-school students' progress in gaining integrated understanding of energy while studying an inquiry-oriented curriculum. The…

  13. Longitudinal Approaches to Stages of Change Measurement: Effects on Cognitive and Behavioral Physical Activity Factors

    ERIC Educational Resources Information Center

    Parker, Philip D.; Martin, Andrew J.; Martinez, Carissa; Marsh, Herbert W.; Jackson, Susan

    2010-01-01

    The transition from school to further education and work is one of immense change that impacts physical activity attitudes and engagement in adulthood. The Stages of Change (SOC) model, which resides under the transtheoretical framework, has been proposed as one way to measure and evaluate physical activity uptake and maintenance. The current…

  14. Measuring Meaningful Learning in the Undergraduate General Chemistry and Organic Chemistry Laboratories: A Longitudinal Study

    ERIC Educational Resources Information Center

    Galloway, Kelli R.; Bretz, Stacey Lowery

    2015-01-01

    Understanding how students learn in the undergraduate chemistry teaching laboratory is an essential component to developing evidence-based laboratory curricula. The Meaningful Learning in the Laboratory Instrument (MLLI) was developed to measure students' cognitive and affective expectations and experiences for learning in the chemistry…

  15. Longitudinal Prediction of Child Outcomes from Differing Measures of Parenting in a Low-Income Sample

    ERIC Educational Resources Information Center

    Zaslow, Martha J.; Weinfield, Nancy S.; Gallagher, Megan; Hair, Elizabeth C.; Ogawa, John R.; Egeland, Byron; Tabors, Patton O.; De Temple, Jeanne M.

    2006-01-01

    This study examined predictions from preschool parenting measures to middle childhood cognitive and socioemotional child outcomes to explore whether parenting assessment methodologies that require more time, training, and expense yield better predictions of child outcomes than less intensive methodologies. Mother-child dyads (N=278) in low-income…

  16. Longitudinal measurements of syrinx size in a rat model of posttraumatic syringomyelia.

    PubMed

    Najafi, Elmira; Bilston, Lynne E; Song, Xin; Bongers, Andre; Stoodley, Marcus A; Cheng, Shaokoon; Hemley, Sarah J

    2016-06-01

    OBJECTIVE Syringomyelia pathophysiology is commonly studied using rodent models. However, in vivo studies of posttraumatic syringomyelia have been limited by the size of animals and lack of reliable noninvasive evaluation techniques. Imaging the rat spinal cord is particularly challenging because the spinal cord diameter is approximately 1-3 mm, and pathological lesions within the spinal cord parenchyma are even smaller. The standard technique has been histological evaluation, but this has its limitations. The aim of the present study was to determine whether syrinx size could be reliably measured using a preclinical high-field MRI animal system in a rat model of posttraumatic syringomyelia. METHODS The authors used an existing rat model of posttraumatic syringomyelia, which was created using a controlled pneumatic compression device to produce the initial spinal cord injury, followed by a subarachnoid injection of kaolin to produce arachnoiditis. T2-weighted MRI was performed on each animal using a 9.4-T scanner at 7, 10, and 13 weeks after injury. Animals were killed and syrinx sizes were calculated from in vivo MRI and histological studies. RESULTS MRI measurements of syrinx volume and length were closely correlated to histological measurements across all time points (Pearson product moment correlation coefficient r = ± 0.93 and 0.79, respectively). CONCLUSIONS This study demonstrates that high-field T2-weighted MRI can be used to measure syrinx size, and data correlate well with syrinx size measured using histological methods. Preclinical MRI may be a valuable noninvasive technique for tracking syrinx formation and enlargement in animal models of syringomyelia. PMID:26918577

  17. How Does Longitudinally Measured Maternal Expressed Emotion Affect Internalizing and Externalizing Symptoms of Adolescents from the General Community?

    ERIC Educational Resources Information Center

    Hale, William W., III; Keijsers, Loes; Klimstra, Theo A.; Raaijmakers, Quinten A. W.; Hawk, Skyler; Branje, Susan J. T.; Frijns, Tom; Wijsbroek, Saskia A. M.; van Lier, Pol; Meeus, Wim H. J.

    2011-01-01

    Background: In previous studies, maternal expressed emotion (EE) has been found to be a good predictor of the course of adolescent internalizing and externalizing symptoms. However, these studies have been cross-section as opposed to longitudinal. The goal of this study is to examine longitudinal data of perceived maternal EE and adolescent…

  18. Healthcare improvement as planned system change or complex responsive processes? a longitudinal case study in general practice

    PubMed Central

    2013-01-01

    Background Interest in how to implement evidence-based practices into routine health care has never been greater. Primary care faces challenges in managing the increasing burden of chronic disease in an ageing population. Reliable prescriptions for translating knowledge into practice, however, remain elusive, despite intense research and publication activity. This study seeks to explore this dilemma in general practice by challenging the current way of thinking about healthcare improvement and asking what can be learned by looking at change through a complexity lens. Methods This paper reports the local level of an embedded case study of organisational change for better chronic illness care over more than a decade. We used interviews, document review and direct observation to explore how improved chronic illness care developed in one practice. This formed a critical case to compare, using pattern matching logic, to the common prescription for local implementation of best evidence and a rival explanation drawn from complexity sciences interpreted through modern sociology and psychology. Results The practice changed continuously over more than a decade to deliver better chronic illness care in line with research findings and policy initiatives – re-designing care processes, developing community linkages, supporting patient self-management, using guidelines and clinical information systems, and integrating nurses into the practice team. None of these improvements was designed and implemented according to an explicit plan in response to a documented gap in chronic disease care. The process that led to high quality chronic illness care exhibited clear complexity elements of co-evolution, non-linearity, self-organisation, emergence and edge of chaos dynamics in a network of agents and relationships where a stable yet evolving way of organizing emerged from local level communicative interaction, power relating and values based choices. Conclusions The current discourse

  19. Accuracy and repeatability of Roentgen stereophotogrammetric analysis (RSA) for measuring knee laxity in longitudinal studies.

    PubMed

    Fleming, B C; Peura, G D; Abate, J A; Beynnon, B D

    2001-10-01

    Roentgen stereophotogrammetric analysis (RSA) can be used to assess temporal changes in anterior-posterior (A-P) knee laxity. However, the accuracy and precision of RSA is dependent on many factors and should be independently evaluated for a particular application. The objective of this study was to evaluate the use of RSA for measuring A-P knee laxity. The specific aims were to assess the variation or "noise" inherent to RSA, to determine the reproducibility of RSA for repeated A-P laxity testing, and to assess the accuracy of these measurements. Two experiments were performed. The first experiment utilized three rigid models of the tibiofemoral joint to assess the noise and to compare digitization errors of two independent examiners. No differences were found in the kinematic outputs of the RSA due to examiner, repeated trials, or the model used. In a second experiment, A-P laxity values between the A-P shear load limits of +/-60 N of five cadaver goat knees were measured to assess the error associated with repeated testing. The RSA laxity values were also compared to those obtained from a custom designed linkage system. The mean A-P laxity values with the knee 30 degrees, 60 degrees, and 90 degrees of flexion for the ACL-intact goat knee (+/-95% confidence interval) were 0.8 (+/-0.25), 0.9 (+/-0.29), and 0.4 (+/-0.22) mm, respectively. In the ACL-deficient knee, the A-P laxity values increased by an order of magnitude to 8.8 (+/-1.39), 7.6 (+/-1.32), and 3.1 (+/-1.20)mm, respectively. No significant differences were found between the A-P laxity values measured by RSA and the independent measurement technique. A highly significant linear relationship (r(2)=0.83) was also found between these techniques. This study suggests that the RSA method is an accurate and precise means to measure A-P knee laxity for repeated testing over time. PMID:11522316

  20. A method for eliminating Faraday rotation in cryostat windows in longitudinal magneto-optical Kerr effect measurements.

    PubMed

    Polewko-Klim, A; Uba, S; Uba, L

    2014-07-01

    A solution to the problem of disturbing effect of the background Faraday rotation in the cryostat windows on longitudinal magneto-optical Kerr effect (LMOKE) measured under vacuum conditions and/or at low temperatures is proposed. The method for eliminating the influence of Faraday rotation in cryostat windows is based on special arrangement of additional mirrors placed on sample holder. In this arrangement, the orientation of the cryostat window is perpendicular to the light beam direction and parallel to an external magnetic field generated by the H-frame electromagnet. The operation of the LMOKE magnetometer with the special sample holder based on polarization modulation technique with a photo-elastic modulator is theoretically analyzed with the use of Jones matrices, and formulas for evaluating of the actual Kerr rotation and ellipticity of the sample are derived. The feasibility of the method and good performance of the magnetometer is experimentally demonstrated for the LMOKE effect measured in Fe/Au multilayer structures. The influence of imperfect alignment of the magnetometer setup on the Kerr angles, as derived theoretically through the analytic model and verified experimentally, is examined and discussed. PMID:25085126

  1. A method for eliminating Faraday rotation in cryostat windows in longitudinal magneto-optical Kerr effect measurements

    SciTech Connect

    Polewko-Klim, A. Uba, S.; Uba, L.

    2014-07-15

    A solution to the problem of disturbing effect of the background Faraday rotation in the cryostat windows on longitudinal magneto-optical Kerr effect (LMOKE) measured under vacuum conditions and/or at low temperatures is proposed. The method for eliminating the influence of Faraday rotation in cryostat windows is based on special arrangement of additional mirrors placed on sample holder. In this arrangement, the orientation of the cryostat window is perpendicular to the light beam direction and parallel to an external magnetic field generated by the H-frame electromagnet. The operation of the LMOKE magnetometer with the special sample holder based on polarization modulation technique with a photo-elastic modulator is theoretically analyzed with the use of Jones matrices, and formulas for evaluating of the actual Kerr rotation and ellipticity of the sample are derived. The feasibility of the method and good performance of the magnetometer is experimentally demonstrated for the LMOKE effect measured in Fe/Au multilayer structures. The influence of imperfect alignment of the magnetometer setup on the Kerr angles, as derived theoretically through the analytic model and verified experimentally, is examined and discussed.

  2. Quality control technique to reduce the variability of longitudinal measurement of hemoglobin mass.

    PubMed

    Gough, C E; Sharpe, K; Ashenden, M J; Anson, J M; Saunders, P U; Garvican, L A; Bonetti, D L; Gore, C J; Prommer, N

    2011-12-01

    The sensitivity of the athlete blood passport to detect blood doping may be improved by the inclusion of total hemoglobin mass (Hb(mass)), but the comparability of Hb(mass) from different laboratories is unknown. To optimize detection sensitivity, the analytical variability associated with Hb(mass) measurement must be minimized. The aim of this study was to investigate the efficacy of using quality controls to minimize the variation in Hb(mass) between laboratories. Three simulated laboratories were set up in one location. Nine participants completed three carbon monoxide (CO) re-breathing tests in each laboratory. One participant completed two CO re-breathing tests in each laboratory. Simultaneously, quality controls containing Low (1-3%) and High (8-11%) concentrations of percent carboxyhemoglobin (%HbCO) were measured to compare hemoximeters in each laboratory. Linear mixed modeling was used to estimate the within-subject variation in Hb(mass), expressed as the coefficient of variation, and to estimate the effect of different laboratories. The analytic variation of Hb(mass) was 2.4% when tests were conducted in different laboratories, which reduced to 1.6% when the model accounted for between-laboratory differences. Adjustment of Hb(mass) values using quality controls achieved a comparable analytic variation of 1.7%. The majority of between-laboratory variation in Hb(mass) originated from the difference between hemoximeters, which could be eliminated using appropriate quality controls. PMID:21535184

  3. Maternal feeding practices predict fruit and vegetable consumption in young children. Results of a 12-month longitudinal study.

    PubMed

    Gregory, Jane E; Paxton, Susan J; Brozovic, Anna M

    2011-08-01

    This study aimed to explore the prospective relationship between maternal feeding practices and young children's frequency of consumption of fruits, vegetables and sweets, and also child weight-for-height z-scores. Participants were 60 mothers who completed questionnaires when their children were 1 year old and again when their children were 2 years old. Regression analyses were performed. After controlling for availability and prior child consumption of the target food, maternal use of pressure to eat at 1 year predicted lower child frequency of fruit consumption at 2 years and approached significance for lower vegetable consumption. Maternal modelling of healthy eating at 1 year predicted higher child frequency of vegetable consumption at 2 years. Restriction did not significantly predict child frequency of consumption of fruits, vegetables or sweets over time. Child weight-for-height scores at 2 years were predicted by weight-for-height at 1 year but not by feeding practices. The findings suggest that maternal feeding practices can influence child eating at a very young age. Interventions should focus on encouraging parents to model healthy eating to promote healthy eating in children. PMID:21569809

  4. Measurement of R = {sigma}{sub L}/{sigma}{sub T} and the Separated Longitudinal and Transverse Structure Functions in the Nucleon Resonance Region

    SciTech Connect

    Yongguang Liang; Michael Christy; Abdellah Ahmidouch; Christopher Armstrong; John Arrington; Arshak Asaturyan; Steven Avery; O. Baker; Douglas Beck; Henk Blok; C.W. Bochna; Werner Boeglin; Peter Bosted; Maurice Bouwhuis; Herbert Breuer; Daniel Brown; Antje Bruell; Roger Carlini; Jinseok Cha; Nicholas Chant; Anthony Cochran; Leon Cole; Samuel Danagoulian; Donal Day; James Dunne; Dipangkar Dutta; Rolf Ent; Howard Fenker; B. Fox; Liping Gan; Haiyan Gao; Kenneth Garrow; David Gaskell; Ashot Gasparian; Don Geesaman; Ronald Gilman; Paul Gueye; Mark Harvey; Roy Holt; Xiaodong Jiang; Mark Jones; Cynthia Keppel; Edward Kinney; Wolfgang Lorenzon; Allison Lung; David Mack; Pete Markowitz; J.W. Martin; Kevin McIlhany; Daniella Mckee; David Meekins; M.A. Miller; Richard Milner; Joseph Mitchell; Hamlet Mkrtchyan; Robert Mueller; Alan Nathan; Gabriel Niculescu; Maria-Ioana Niculescu; Thomas O'neill; Vassilios Papavassiliou; Stephen Pate; Rodney Piercey; David Potterveld; Ronald Ransome; Joerg Reinhold; E. Rollinde; Oscar Rondon-Aramayo; Philip Roos; Adam Sarty; Reyad Sawafta; Elaine Schulte; Edwin Segbefia; C. Smith; Samuel Stepanyan; Steffen Strauch; Vardan Tadevosyan; Liguang Tang; Raphael Tieulent; Vladas Tvaskis; Alicia Uzzle; William Vulcan; Stephen Wood; Feng Xiong; Lulin Yuan; Markus Zeier; Benedikt Zihlmann; Vitaliy Ziskin

    2004-10-01

    We report on a detailed study of longitudinal strength in the nucleon resonance region, presenting new results from inclusive electron-proton cross sections measured at Jefferson Lab Hall C in the four-momentum transfer range 0.2 < Q{sup 2} < 5.5 GeV{sup 2}. The data have been used to accurately perform over 170 Rosenbluth-type longitudinal/transverse separations. The precision R = {sigma}{sub L}/{sigma}{sub T} data are presented here, along with the first separate values of the inelastic structure functions F{sub 1} and F{sub L} in this regime. The resonance longitudinal component is found to be significant. With the new data, quark-hadron duality is observed above Q{sup 2} = 1 GeV{sup 2} in the separated structure functions independently.

  5. Impact of uncertainty in longitudinal T1 measurements on quantification of dynamic contrast-enhanced MRI.

    PubMed

    Aryal, Madhava P; Chenevert, Thomas L; Cao, Yue

    2016-04-01

    The objective of this study was to assess the uncertainty in T1 measurement, by estimating the repeatability coefficient (RC) from two repeated scans, in normal appearing brain tissues employing two different T1 mapping methods. All brain MRI scans were performed on a 3 T MR scanner in 10 patients who had low grade/benign tumors and partial brain radiation therapy (RT) without chemotherapy, at pre-RT, 3 weeks into RT, end RT (6 weeks) and 11, 33, and 85 weeks after RT. T1-weighted images were acquired using (1) a spoiled gradient echo sequence with two flip angles (2FA: 5° and 15°) and (2) a progressive saturation recovery sequence (pSR) with five different TR values (100-2000 ms). Manually drawn volumes of interest (VOIs) included left and right normal putamen and thalamus in gray matter, and frontal and parietal white matter, which were distant from tumors and received a total of accumulated radiation doses less than 5 Gy at 3 weeks. No significant changes or even trends in mean T1 from pre-RT to 3 weeks into RT in these VOIs (p ≥ 0.11, Wilcoxon sign test) allowed us to calculate the repeatability statistics of between-subject means of squares, within-subject means of squares, F-score, and RC. The 2FA method produced RCs in the range of (9.7-11.7)% in gray matter and (12.2-14.5)% in white matter; while the pSR method led to RCs ranging from 10.9 to 17.9% in gray matter and 7.5 to 10.3% in white matter. The overall mean (±SD) RCs produced by the two methods, 12.0 (±1.6)% for 2FA and 12.0 (±3.8)% for pSR, were not significantly different (p = 0.97). A similar repeatability in T1 measurement produced by the time efficient 2FA method compared with the time consuming pSR method demonstrates that the 2FA method is desirable to integrate into dynamic contrast-enhanced MRI for rapid acquisition. PMID:27358934

  6. Measurement of the longitudinal deuteron spin-structure function in deep-inelastic scattering

    SciTech Connect

    Bauer, J.M.

    1996-09-01

    Experiment E143 at SLAC performed deep-inelastic scattering measurements with polarized electrons incident on polarized protons and deuterons. The data for the beam energy of 29 GeV cover the kinematical range of x{sub Bj} > 0.03 and 1 < Q{sup 2} < 12 GeV{sup 2}. From these data, the spin-dependent structure functions g{sub 1} were determined. This dissertation describes the experiment and its analysis and discusses the results. The measured integral of g{sub 1}{sup d} over x from x = 0 to x = 1 is {Gamma}{sub 1}{sup d} = 0.046 {+-} 0.003 (stat){+-}0.004 (syst) at Q{sup 2} = 3 GeV{sup 2} and disagrees by more than three standard deviations with the prediction of the Ellis-Jaffe, sum rule. The data suggest that the quark contribution to the nucleon helicity is 0.35 {+-} 0.05. From the proton data of the same experiment, the integral over the proton spin-structure functional g{sub 1}{sup d} was determined to be {Gamma}{sub 1}{sup p} = 0.127 {+-} 0.003(stat){+-}0.008(syst). By Combining the deuteron data with the proton data, the integral {Gamma}{sub 1}{sup n} was extracted as {minus}0.027 {+-} 0.008 (stat){+-}0.010 (syst). The integral {Gamma}{sub 1}{sup p} {minus} {Gamma}{sub 1}{sup n} is 0.154{+-}0.010(stat) {+-}0.016 (syst) according to the E143 analysis. This result agrees with the important Bjorken sum rule of 0.171 {+-} 0.009 at Q{sup 2} = 3 GeV{sup 2} within less than one standard deviation. Furthermore, results of a separate analysis involving GLAP evolution equations are shown. Data were also collected for beam energies of 16.2 and 9.7 GeV, Results for g{sub 1} at these energies are presented.

  7. Acoustic Radiation Force Impulse Measurement in Renal Transplantation: A Prospective, Longitudinal Study With Protocol Biopsies.

    PubMed

    Lee, Juhan; Oh, Young Taik; Joo, Dong Jin; Ma, Bo Gyoung; Lee, A-lan; Lee, Jae Geun; Song, Seung Hwan; Kim, Seung Up; Jung, Dae Chul; Chung, Yong Eun; Kim, Yu Seun

    2015-09-01

    Interstitial fibrosis and tubular atrophy (IF/TA) is a common cause of kidney allograft loss. Several noninvasive techniques developed to assess tissue fibrosis are widely used to examine the liver. However, relatively few studies have investigated the use of elastographic methods to assess transplanted kidneys. The aim of this study was to explore the clinical implications of the acoustic radiation force impulse (ARFI) technique in renal transplant patients. A total of 91 patients who underwent living donor renal transplantation between September 2010 and January 2013 were included in this prospective study. Shear wave velocity (SWV) was measured by ARFI at baseline and predetermined time points (1 week and 6 and 12 months after transplantation). Protocol biopsies were performed at 12 months. Instead of reflecting IF/TA, SWVs were found to be related to time elapsed after transplantation. Mean SWV increased continuously during the first postoperative year (P < 0.001). In addition, mixed model analysis showed no correlation existed between SWV and serum creatinine (r = -0.2426, P = 0.0771). There was also no evidence of a relationship between IF/TA and serum creatinine (odds ratio [OR] = 1.220, P = 0.7648). Furthermore, SWV temporal patterns were dependent on the kidney weight to body weight ratio (KW/BW). In patients with a KW/BW < 3.5 g/kg, mean SWV continuously increased for 12 months, whereas it decreased after 6 months in those with a KW/BW ≥ 3.5 g/kg.No significant correlation was observed between SWV and IF/TA or renal dysfunction. However, SWV was found to be related to the time after transplantation. Renal hemodynamics influenced by KW/BW might impact SWV values. PMID:26426636

  8. Objectively measured physical activity and sedentary behaviour and ankle brachial index: Cross-sectional and longitudinal associations in older men

    PubMed Central

    Parsons, Tessa J.; Sartini, Claudio; Ellins, Elizabeth A.; Halcox, Julian P.J.; Smith, Kirsten E.; Ash, Sarah; Lennon, Lucy T.; Wannamethee, S. Goya; Lee, I-Min; Whincup, Peter H.; Jefferis, Barbara J.

    2016-01-01

    Background Associations between bouts of physical activity (PA), sedentary behaviour (SB) and cardiovascular disease, and their mutual independence are not well defined. A low ankle brachial index (ABI ≤0.9) indicates peripheral arterial disease (PAD) and is predictive of cardiovascular events and functional impairment. We investigated the independence of PA and SB and the importance of bout duration in relation to ABI using objective measures. Methods 945 men from the British Regional Heart Study, mean age 78.4 y, had concurrent measurements of ABI (Vicorder) and physical activity (Actigraph GT3X accelerometer); 427 men also had accelerometer measurements one year previously and contributed data to longitudinal analyses. Results and conclusion In cross-sectional analyses, after adjusting for covariates each extra 10 min of moderate and vigorous PA per day was associated with an OR of 0.81 (95% CI 0.72, 0.91) for a low ABI, a stronger association than for light PA (OR 0.85, 95% CI 0.75, 0.98). Each extra 30 min of SB was associated with an OR of 1.19 (95% CI 1.07, 1.33) for a low ABI. Associations between moderate and vigorous PA and ABI persisted after adjustment for light PA or SB. Bout lengths for PA and SB were not associated with a low ABI. One year changes in PA or SB were not associated with low ABI. All physical activity and lower levels of SB, regardless of bout duration were inversely associated with ABI; more intense PA showed a stronger association. No associations between changes in PA and ABI were observed, but power may have been limited. PMID:26854973

  9. A Robust System for Longitudinal Knee Joint Edema and Blood Flow Assessment Based on Vector Bioimpedance Measurements.

    PubMed

    Hersek, Sinan; Töreyin, Hakan; Inan, Omer T

    2016-06-01

    We present a robust vector bioimpedance measurement system for longitudinal knee joint health assessment, capable of acquiring high resolution static (slowly varying over the course of hours to days) and dynamic (rapidly varying on the order of milli-seconds) bioresistance and bioreactance signals. Occupying an area of 78×90 mm(2) and consuming 0.25 W when supplied with ±5 V, the front-end achieves a dynamic range of 345 Ω and noise floor of 0.018 mΩrms (resistive) and 0.055 mΩrms (reactive) within a bandwidth of 0.1-20 Hz. A microcontroller allows real-time calibration to minimize errors due to environmental variability (e.g., temperature) that can be experienced outside of lab environments, and enables data storage on a micro secure digital card. The acquired signals are then processed using customized physiology-driven algorithms to extract musculoskeletal (edema) and cardiovascular (local blood volume pulse) features from the knee joint. In a feasibility study, we found statistically significant differences between the injured and contralateral static knee impedance measures for two subjects with recent unilateral knee injury compared to seven controls. Specifically, the impedance was lower for the injured knees, supporting the physiological expectations for increased edema and damaged cell membranes. In a second feasibility study, we demonstrate the sensitivity of the dynamic impedance measures with a cold-pressor test, with a 20 mΩ decrease in the pulsatile resistance associated with increased downstream peripheral vascular resistance. The proposed system will serve as a foundation for future efforts aimed at quantifying joint health status continuously during normal daily life. PMID:26841413

  10. Measurement of the impact of atopic dermatitis on patients' quality of life: a cross-sectional and longitudinal questionnaire study using the Japanese version of Skindex-16.

    PubMed

    Higaki, Yuko; Kawamoto, Kyoko; Kamo, Toshiko; Ueda, Shu; Arikawa, Junko; Kawashima, Makoto

    2004-12-01

    The impact of atopic dermatitis on patients' quality of life was measured using the Japanese version of Skindex-16 in a cross-sectional and longitudinal questionnaire study. One hundred sixty-two adult patients completed Skindex-16 and were followed-up with a standard medical therapy. Three to six months after the initial testing, 135 (83.3%) of the patients again completed Skindex-16 and also answered a general question about whether their skin condition had improved, remained the same, or become worse. The scores of Skindex-16 of 162 patients with atopic dermatitis were significantly higher than those of patients with isolated lesions, particularly in the Symptoms and Emotions scales. Patients with severe atopic dermatitis showed significantly higher scores in the three scales (Symptoms, Emotions, and Functioning), and there was a significant positive correlation between the severity and the 3-scale scores. After the follow-up period, 78 of 135 patients (57.8%) reported that their skin condition had improved. Forty-six patients (34.1%) reported that their skin condition had remained the same, and 11 (8.1%) became worse. Among the patients who said their dermatitis had improved, the scores of Skindex-16 significantly decreased. On the other hand, patients who reported their dermatitis worse showed an increase in the scores. These findings suggest that Skindex-16 responsively measures the disease severity and clinical change in the estimation of the effects of atopic dermatitis on patients' quality of life. This practical and sensitive, skin-disease specific, quality-of-life instrument is valuable for assessing patients' outcomes, especially their response to therapy, and is useful to understanding and improving the quality of life of patients suffering with atopic dermatitis. PMID:15801261

  11. Objectively measured physical activity and longitudinal changes in adolescent body fatness: an observational cohort study*

    PubMed Central

    Collings, P. J.; Wijndaele, K.; Corder, K.; Westgate, K.; Ridgway, C. L.; Sharp, S. J.; Atkin, A. J.; Stephen, A. M.; Bamber, D.; Goodyer, I.; Brage, S.

    2015-01-01

    Summary Background The data regarding prospective associations between physical activity (PA) and adiposity in youth are inconsistent. Objective The objective of this study was to investigate associations between baseline levels of objectively measured PA and changes in adiposity over 2.5 years from mid‐to‐late adolescence. Methods This was an observational cohort study in 728 school students (43% boys) from Cambridgeshire, United Kingdom. Fat mass index (FMI, kg m−2) was estimated at baseline (mean ± standard deviation age: 15 ± 0.3 years) and follow‐up (17.5 ± 0.3 years) by anthropometry and bioelectrical impedance. Habitual PA was assessed at baseline by ≥3 d combined heart rate and movement sensing. Average daily PA energy expenditure (PAEE) and the time (min d−1) spent in light, moderate and vigorous intensity PA (LPA, MPA and VPA, respectively) was estimated. Multilevel models were used to investigate associations between baseline PA and change in FMI (ΔFMI). Adjustment for baseline age, sex, follow‐up duration, area‐level socioeconomic status, season of PA assessment, sedentary time, energy intake and sleep duration was made; baseline FMI was also added in a second model. Results FMI increased significantly over follow‐up (0.6 ± 1.2 kg m−2, P < 0.001). Baseline PAEE and LPA positively predicted ΔFMI in overfat participants (P ≤ 0.030), as did VPA in initially normal fat participants (P ≤ 0.044). There were further positive associations between PAEE and ΔFMI in normal fat participants, and between MPA and ΔFMI in both fat groups, when adjusted for baseline FMI (P ≤ 0.024). Conclusions Baseline PAEE and its subcomponents were positively associated with small and unlikely clinically relevant increases in ΔFMI. These counter‐intuitive findings may be explained by behavioural changes during the course of study follow‐up. PMID:25919340

  12. Longitudinal Inter-Comparison of Modeled and Measured West Greenland Ice Sheet Meltwater Runoff Losses (2004-2014)

    NASA Astrophysics Data System (ADS)

    Moustafa, S.; Rennermalm, A. K.; Tedesco, M.; Mote, T. L.; Koenig, L.; Smith, L. C.; Hagedorn, B.; Overeem, I.; Sletten, R. S.; Mikkelsen, A. B.; Hasholt, B.; Hall, D. K.

    2015-12-01

    Increased surface meltwater runoff, that exits the Greenland ice sheet (GrIS) margin via supra-, en-, and sub-glacial drainage networks into fjords, pro-glacial lakes and rivers, accounts for half or more of total mass loss. Despite its importance, modeled meltwater runoff fluxes are poorly constrained, primarily due to a lack of direct in situ observations. Here, we present the first ever longitudinal (north-south) inter-comparison of a multi-year dataset (2004-2014) of discharge for four drainage basins - Watson, Akuliarusiarsuup Kuua, Naujat Kuat, and North Rivers - along West Greenland. These in situ hydrologic measurements are compared with modeled runoff output from Modèle Atmosphérique Régional (MAR) regional climate model, and the performance of the model is examined. An analysis of the relationship between modeled and actual ice sheet runoff patterns is assessed, and provides insight into the model's ability to capture inter-annual and intra-annual variability, spatiotemporal patterns, and extreme melt events. This study's findings will inform future development and parameterization of ice sheet surface mass balance models.

  13. A Preference Based Measure of Complementary Feeding Quality: Application to the Avon Longitudinal Study of Parents and Children

    PubMed Central

    Mittinty, Murthy N.; Golley, Rebecca K.; Smithers, Lisa G.; Brazionis, Laima; Lynch, John W.

    2013-01-01

    This paper presents the development of the Complementary Feeding Utility Index (CFUI), a composite index aimed to measure adherence to infant feeding guidelines. Through an axiomatic characterization this paper shows the advantages in using the CFUI are the following: it avoids the use of arbitrary cut-offs, and by converting observed diet preferences into utilities, summing the score is meaningful. In addition, as the CFUI is designed to be scored continuously, it allows the transition from intake of beneficial foods (in low quantities) and intake of detrimental foods (in high quantities) to be more subtle. The paper first describes the rationale being the development of the CFUI and then elaborates on the methodology used to develop the CFUI, including the process of selecting the components. The methodology is applied to data collected from the Avon Longitudinal Study of Parents and Children to show the advantages of the CFUI over traditional diet index approaches. Unlike traditional approaches, the distribution of the CFUI does not peak towards mean value but distributes evenly towards the tails of the distribution. PMID:24155886

  14. Qualification tests and electrical measurements: Practice and problems

    NASA Technical Reports Server (NTRS)

    Smokler, M. I.

    1983-01-01

    As part of the Flat-Plate Solar Array Project, 138 different module designs were subjected to qualification tests. Electrical measurements were subjected on well over a thousand modules representing more than 150 designs. From this experience, conclusions are drawn regarding results and problems, with discussion of the need for change or improvement. The qualification test sequence incuded application of environmental and electrical stresses to the module. With few exceptions, the tests have revealed defects necessitation of environmental and electrical stresses to the module. With few exceptions, the tests have revealed defects necessitating module design or process changes. However, the continued need for these tests may be questioned on the basis of technical and logistical factors. Technically, the current test sequence does not cover all design characteristics, does not include all field conditions and is not known to represent the desired 30-year module life. Logistically, the tests are time-consuming and costly, and there is a lack of, fully qualified independent test organizations. Alternatives to the current test program include simplification based on design specification and site environment, and/or the use of warranties or other commercial practices.

  15. Exploring the beliefs and practices of five preservice secondary science teachers from recruitment through induction in a university preparation program: A longitudinal study

    NASA Astrophysics Data System (ADS)

    Fletcher, Steven Samuel

    This three-year longitudinal study explores the evolving beliefs and practices of five prospective secondary science teachers in a university preparation program from recruitment through their first year in the classroom. As an interpretive qualitative study, the format for data collection and analysis utilizes a case-study methodology with cross-case analysis. Data was collected through semi-structured interviews, collected artifacts, and classroom observations. There are a number of important conclusions from this study. First, the teachers' beliefs about teaching initially shift to a contemporary focus during the program, but ultimately return to a didactic orientation by their first year in the classroom. At the same time, the teachers' beliefs about learning remain consistently more contemporary in nature. Second, the participants believe that they practice teaching science as inquiry at a higher level than are indicated by researcher observations. Third, while participants value advanced content and educational theory coursework, they do not always see the link between these experiences and their development as science teachers. Fourth, the findings from this study reveal that internal and external contextual factors impacted, to varying degrees, the development of the science teachers. The findings from this study contribute to a deeper understanding of the development of science teachers from preservice education to the induction years, which indicates a pattern that is not linear. The findings from this study also reinforce the importance of internal and external contextual factors on the development of science teachers. Ultimately, this study is important to the field of secondary science teacher education as it depicts the complex interactions between the individual, the preparation program, and the school placements that impact the beliefs and practices of preservice and beginning teachers.

  16. Measurement of longitudinal strain and estimation of peel stress in adhesive-bonded single-lap joint of CFRP adherend using embedded FBG sensor

    NASA Astrophysics Data System (ADS)

    Ning, X.; Murayama, H.; Kageyama, K.; Uzawa, K.; Wada, D.

    2012-04-01

    In this research, longitudinal strain and peel stress in adhesive-bonded single-lap joint of carbon fiber reinforced plastics (CFRP) were measured and estimated by embedded fiber Bragg grating (FBG) sensor. Two unidirectional CFRP substrates were bonded by epoxy to form a single-lap configuration. The distributed strain measurement system is used. It is based on optical frequency domain reflectometry (OFDR), which can provide measurement at an arbitrary position along FBG sensors with the high spatial resolution. The longitudinal strain was measured based on Bragg grating effect and the peel stress was estimated based on birefringence effect. Special manufacturing procedure was developed to ensure the embedded location of FBG sensor. A portion of the FBG sensor was embedded into one of CFRP adherends along fiber direction and another portion was kept free for temperature compensation. Photomicrograph of cross-section of specimen was taken to verify the sensor was embedded into proper location after adherend curing. The residual strain was monitored during specimen curing and adhesive joint bonding process. Tensile tests were carried out and longitudinal strain and peel stress of the bondline are measured and estimated by the embedded FBG sensor. A two-dimensional geometrically nonlinear finite element analysis was performed by ANSYS to evaluate the measurement precision.

  17. Impact of air pollution on pulmonary function and respiratory symptoms in children. Longitudinal repeated-measures study

    PubMed Central

    2010-01-01

    Background Salamanca, Mexico occupied fourth place nationally in contaminating emissions. The aim of the study was to determine the impact of air pollution on the frequency of pulmonary function alterations and respiratory symptoms in school-age children in a longitudinal repeated-measures study. Methods We recruited a cohort of 464 children from 6 to 14 years of age, from two schools differing in distance from the major stationary air pollution sources. Spirometry, respiratory symptoms and air pollutants (O3, SO2, NO, NO2, NOx, PM10,) were obtained for each season. Mixed models for continuous variables and multilevel logistic regression for respiratory symptoms were fitted taking into account seasonal variations in health effects according to air pollution levels. Results Abnormalities in lung function and frequency of respiratory symptoms were higher in the school closer to major stationary air pollution sources than in the distant school. However, in winter differences on health disappeared. The principal alteration in lung function was the obstructive type, which frequency was greater in those students with greater exposure (10.4% vs. 5.3%; OR = 1.95, 95% CI 1.0-3.7), followed by the mixed pattern also more frequent in the same students (4.1% vs. 0.9%; OR = 4.69, 95% CI, 1.0-21.1). PM10 levels were the most consistent factor with a negative relationship with FVC, FEV1 and PEF but with a positive relationship with FEV1/FVC coefficient according to its change per 3-month period. Conclusions Students from the school closer to major stationary air pollution sources had in general more respiratory symptoms than those from the distant school. However, in winter air pollution was generalized in this city and differences in health disappeared. PM10 levels were the most consistent factor related to pulmonary function according, to its change per 3-month period. PMID:21106102

  18. Measurement of the longitudinal cross-section using the direction of the thrust axis in hadronic events at LEP

    NASA Astrophysics Data System (ADS)

    OPAL Collaboration; Abbiendi, G.; Ackerstaff, K.; Alexander, G.; Allison, J.; Altekamp, N.; Anderson, K. J.; Anderson, S.; Arcelli, S.; Asai, S.; Ashby, S. F.; Axen, D.; Azuelos, G.; Ball, A. H.; Barberio, E.; Barlow, R. J.; Bartoldus, R.; Batley, J. R.; Baumann, S.; Bechtluft, J.; Behnke, T.; Bell, K. W.; Bella, G.; Bellerive, A.; Bentvelsen, S.; Bethke, S.; Betts, S.; Biebel, O.; Biguzzi, A.; Bird, S. D.; Blobel, V.; Bloodworth, I. J.; Bobinski, M.; Bock, P.; Böhme, J.; Bonacorsi, D.; Boutemeur, M.; Braibant, S.; Bright-Thomas, P.; Brigliadori, L.; Brown, R. M.; Burckhart, H. J.; Burgard, C.; Bürgin, R.; Capiluppi, P.; Carnegie, R. K.; Carter, A. A.; Carter, J. R.; Chang, C. Y.; Charlton, D. G.; Chrisman, D.; Ciocca, C.; Clarke, P. E. L.; Clay, E.; Cohen, I.; Conboy, J. E.; Cooke, O. C.; Couyoumtzelis, C.; Coxe, R. L.; Cuffiani, M.; Dado, S.; Dallavalle, G. M.; Davis, R.; de Jong, S.; del Pozo, L. A.; de Roeck, A.; Desch, K.; Dienes, B.; Dixit, M. S.; Dubbert, J.; Duchovni, E.; Duckeck, G.; Duerdoth, I. P.; Eatough, D.; Estabrooks, P. G.; Etzion, E.; Evans, H. G.; Fabbri, F.; Fanti, M.; Faust, A. A.; Fiedler, F.; Fierro, M.; Fleck, I.; Folman, R.; Fürtjes, A.; Futyan, D. I.; Gagnon, P.; Gary, J. W.; Gascon, J.; Gascon-Shotkin, S. M.; Gaycken, G.; Geich-Gimbel, C.; Giacomelli, G.; Giacomelli, P.; Gibson, V.; Gibson, W. R.; Gingrich, D. M.; Glenzinski, D.; Goldberg, J.; Gorn, W.; Grandi, C.; Gross, E.; Grunhaus, J.; Gruwé, M.; Hanson, G. G.; Hansroul, M.; Hapke, M.; Harder, K.; Hargrove, C. K.; Hartmann, C.; Hauschild, M.; Hawkes, C. M.; Hawkings, R.; Hemingway, R. J.; Herndon, M.; Herten, G.; Heuer, R. D.; Hildreth, M. D.; Hill, J. C.; Hillier, S. J.; Hobson, P. R.; Hocker, A.; Homer, R. J.; Honma, A. K.; Horváth, D.; Hossain, K. R.; Howard, R.; Hüntemeyer, P.; Hutchcroft, D. E.; Igo-Kemenes, P.; Imrie, D. C.; Ishii, K.; Jacob, F. R.; Jawahery, A.; Jeremie, H.; Jimack, M.; Jones, C. R.; Jovanovic, P.; Junk, T. R.; Karlen, D.; Kartvelishvili, V.; Kawagoe, K.; Kawamoto, T.; Kayal, P. I.; Keeler, R. K.; Kellogg, R. G.; Kennedy, B. W.; Klier, A.; Kluth, S.; Kobayashi, T.; Kobel, M.; Koetke, D. S.; Kokott, T. P.; Kolrep, M.; Komamiya, S.; Kowalewski, R. V.; Kress, T.; Krieger, P.; von Krogh, J.; Kuhl, T.; Kyberd, P.; Lafferty, G. D.; Lanske, D.; Lauber, J.; Lautenschlager, S. R.; Lawson, I.; Layter, J. G.; Lazic, D.; Lee, A. M.; Lellouch, D.; Letts, J.; Levinson, L.; Liebisch, R.; List, B.; Littlewood, C.; Lloyd, A. W.; Lloyd, S. L.; Loebinger, F. K.; Long, G. D.; Losty, M. J.; Ludwig, J.; Liu, D.; Macchiolo, A.; MacPherson, A.; Mader, W.; Mannelli, M.; Marcellini, S.; Markopoulos, C.; Martin, A. J.; Martin, J. P.; Martinez, G.; Mashimo, T.; Mättig, P.; McDonald, W. J.; McKenna, J.; McKigney, E. A.; McMahon, T. J.; McPherson, R. A.; Meijers, F.; Menke, S.; Merritt, F. S.; Mes, H.; Meyer, J.; Michelini, A.; Mihara, S.; Mikenberg, G.; Miller, D. J.; Mir, R.; Mohr, W.; Montanari, A.; Mori, T.; Nagai, K.; Nakamura, I.; Neal, H. A.; Nellen, B.; Nisius, R.; O'Neale, S. W.; Oakham, F. G.; Odorici, F.; Ogren, H. O.; Oreglia, M. J.; Orito, S.; Pálinkás, J.; Pásztor, G.; Pater, J. R.; Patrick, G. N.; Patt, J.; Perez-Ochoa, R.; Petzold, S.; Pfeifenschneider, P.; Pilcher, J. E.; Pinfold, J.; Plane, D. E.; Poffenberger, P.; Polok, J.; Przybycień , M.; Rembser, C.; Rick, H.; Robertson, S.; Robins, S. A.; Rodning, N.; Roney, J. M.; Roscoe, K.; Rossi, A. M.; Rozen, Y.; Runge, K.; Runolfsson, O.; Rust, D. R.; Sachs, K.; Saeki, T.; Sahr, O.; Sang, W. M.; Sarkisyan, E. K. G.; Sbarra, C.; Schaile, A. D.; Schaile, O.; Scharf, F.; Scharff-Hansen, P.; Schieck, J.; Schmitt, B.; Schmitt, S.; Schöning, A.; Schröder, M.; Schumacher, M.; Schwick, C.; Scott, W. G.; Seuster, R.; Shears, T. G.; Shen, B. C.; Shepherd-Themistocleous, C. H.; Sherwood, P.; Siroli, G. P.; Sittler, A.; Skuja, A.; Smith, A. M.; Snow, G. A.; Sobie, R.; Söldner-Rembold, S.; Sproston, M.; Stahl, A.; Stephens, K.; Steuerer, J.; Stoll, K.; Strom, D.; Ströhmer, R.; Surrow, B.; Talbot, S. D.; Tanaka, S.; Taras, P.; Tarem, S.; Teuscher, R.; Thiergen, M.; Thomson, M. A.; von Törne, E.; Torrence, E.; Towers, S.; Trigger, I.; Trócsányi, Z.; Tsur, E.; Turcot, A. S.; Turner-Watson, M. F.; van Kooten, R.; Vannerem, P.; Verzocchi, M.; Voss, H.; Wäckerle, F.; Wagner, A.; Ward, C. P.; Ward, D. R.; Watkins, P. M.; Watson, A. T.; Watson, N. K.; Wells, P. S.; Wermes, N.; White, J. S.; Wilson, G. W.; Wilson, J. A.; Wyatt, T. R.; Yamashita, S.; Yekutieli, G.; Zacek, V.; Zer-Zion, D.

    1998-11-01

    In the process e+e--->hadrons, one of the effects of gluon emission is to modify the (1+cos2θ) form of the angular distribution of the thrust axis, an effect which may be quantified by the longitudinal cross-section. Using the OPAL detector at LEP, we have determined the longitudinal to total cross-section ratio to be σL/σtot=0.0127+/- 0.0016+/-0.0013 at the parton level, in good agreement with the expectation of QCD computed to ≀(αs2). Comparisons at the hadron level with Monte Carlo models are presented. The dependence of the longitudinal cross-section on the value of thrust has also been studied, and provides a new test of QCD.

  19. Exploring the Implementation and Use of Outcome Measurement in Practice: A Qualitative Study

    ERIC Educational Resources Information Center

    Skeat, J.; Perry, A.

    2008-01-01

    Background: Outcome measurement is important to clinical practice--yet outcome many speech and language therapists find it difficult to apply measures in practice, and not all clinicians and services have been able to implement and/or use outcome measurement successfully. To date there has been little research to explain why implementation is…

  20. Surface-NMR measurements of the longitudinal relaxation time T1 in a homogeneous sand aquifer in Skive, Denmark

    NASA Astrophysics Data System (ADS)

    Walbrecker, Jan O.; Behroozmand, Ahmad A.

    2012-12-01

    Surface nuclear magnetic resonance (surface NMR) is a geophysical technique used in the exploration of shallow aquifers. It is based on measuring the NMR response of water molecules to excitation by electromagnetic pulses. By increasing the moment of applied pulses, successively deeper regions of an aquifer can be probed. The longitudinal relaxation time T1, determined from the NMR experiment, depends on pore size and can be potentially used to estimate hydraulic conductivity. A novel scheme was recently proposed that was shown theoretically to be more reliable for acquiring surface-NMR T1 data than traditional acquisition. In this proof-of-concept study we provide the first empirical evidence for the superiority of the novel scheme. We chose a survey site close to Skive, Denmark, where proximate boreholes indicate a homogeneous sandy aquifer in the top 30 m. The homogeneous composition implies that the distribution of pore sizes does not vary significantly across the formation. Because pore size is reflected by the T1 relaxation time, we therefore assume that the homogeneous aquifer can be characterized by a single T1 independent of the applied pulse moment (i.e., sampled depth region)—this is the benchmark condition we tested with our surface-NMR measurements. We collected surface-NMR T1 data employing the traditional as well as the novel acquisition scheme at various pulse moments. For each pulse moment we infer a T1 relaxation time based on extensively sampled data (14 delay-time data points). The T1 relaxation times obtained using the novel scheme show a constant value of about 820 ms (± 38 ms) for all pulse moments. In contrast, the T1 relaxation times determined using the traditional scheme vary significantly between 530 and 750 ms with pulse moment, which in an inversion would result in a spatial variation of T1 across the aquifer. The results based on the novel scheme are consistent with a homogeneous aquifer, which we expect based on the borehole

  1. A longitudinal examination of the measurement properties and predictive utility of the Center for Epidemiologic Studies Depression Scale among North American Indigenous adolescents.

    PubMed

    Armenta, Brian E; Sittner Hartshorn, Kelley J; Whitbeck, Les B; Crawford, Devan M; Hoyt, Dan R

    2014-12-01

    We examined the longitudinal measurement properties and predictive utility of the Center for Epidemiologic Studies Depression Scale (CES-D) from early to late adolescence among a sample of North American Indigenous youths. Participants were 632 North American Indigenous adolescents (n = 632; 50.3% girls; M age at baseline = 11.11 years) participating in an 8-year, 8-wave longitudinal study. Via in-person interviews, participants completed the CES-D at Waves 1, 3, 5, and 7, and the major depressive disorder (MDD) module of the Diagnostic Interview Schedule for Children at Waves 1, 4, 6, and 8. Confirmatory factor analyses indicated that responses to the CES-D were similarly explained by 2-, 3-, and 4-factor models, as well as a 1-factor model with correlations between the error variances for the positively worded items. Longitudinal measurement equivalence analyses indicated full structural (i.e., factor structure), metric (i.e., factor loadings), and scalar (i.e., observed item intercepts) equivalence for each factor structure. Substantive analyses showed that the CES-D was significantly associated with MDD both concurrently and prospectively, although these effects were smaller than might be expected. Finally, the CES-D negative affect and somatic complaints subscales were the strongest and most consistent predictors of MDD. Among our sample of North American Indigenous youths, the measurement properties of the CES-D were stable from early to late adolescence. Moreover, somatic difficulties and depressed affect were the strongest predictors of MDD. PMID:25181394

  2. A Longitudinal Examination of the Measurement Properties and Predictive Utility of the Center for Epidemiologic Studies Depression Scale Among North American Indigenous Adolescents

    PubMed Central

    Armenta, Brian E.; Sittner Hartshorn, Kelley J.; Whitbeck, Les B.; Crawford, Devan M.; Hoyt, Dan R.

    2014-01-01

    We examined the longitudinal measurement properties and predictive utility of the Center for Epidemiologic Studies Depression Scale (CES-D) from early to late adolescence among a sample of North American Indigenous youths. Participants were 632 North American Indigenous adolescents (n = 632; 50.3% girls; M age at baseline = 11.11 years) participating in an 8-year, 8-wave longitudinal study. Via in-person interviews, participants completed the CES-D at Waves 1, 3, 5, and 7, and the major depressive disorder (MDD) module of the Diagnostic Interview Schedule for Children at Waves 1, 4, 6, and 8. Confirmatory factor analyses indicated that responses to the CES-D were similarly explained by 2-, 3-, and 4-factor models, as well as a 1-factor model with correlations between the error variances for the positively worded items. Longitudinal measurement equivalence analyses indicated full structural (i.e., factor structure), metric (i.e., factor loadings), and scalar (i.e., observed item intercepts) equivalence for each factor structure. Substantive analyses showed that the CES-D was significantly associated with MDD both concurrently and prospectively, although these effects were smaller than might be expected. Finally, the CES-D negative affect and somatic complaints subscales were the strongest and most consistent predictors of MDD. Among our sample of North American Indigenous youths, the measurement properties of the CES-D were stable from early to late adolescence. Moreover, somatic difficulties and depressed affect were the strongest predictors of MDD. PMID:25181394

  3. Measuring Effectiveness in Transfer Practices for Adult Learners

    ERIC Educational Resources Information Center

    Dougherty, B. Christopher

    2009-01-01

    The Research to Practice (RTP) column in "The Journal of Continuing Higher Education" has recently focused on evaluation methods that continuing education (CE) units can utilize, reports on surveys of CE practitioners, and recommendations for research on dynamics that impact CE programs and the students enrolling in them. In this article, the…

  4. Semi-Spontaneous Oral Text Production: Measurements in Clinical Practice

    ERIC Educational Resources Information Center

    Lind, Marianne; Kristoffersen, Kristian Emil; Moen, Inger; Simonsen, Hanne Gram

    2009-01-01

    Functionally relevant assessment of the language production of speakers with aphasia should include assessment of connected speech production. Despite the ecological validity of everyday conversations, more controlled and monological types of texts may be easier to obtain and analyse in clinical practice. This article discusses some simple…

  5. Longitudinal Lisfranc injury.

    PubMed

    Oak, Nikhil R; Manoli, Arthur; Holmes, James R

    2014-01-01

    Most Lisfranc or tarsometatarsal (TMT) joint injuries result from a horizontally directed force in which the metatarsals are displaced relative to the midfoot. The injury pattern that is described in this article is one of a longitudinal force through the first ray and cuneiform. A reliable measure to recognize the longitudinal Lisfranc variant injury has been the height difference between the distal articular surfaces of the first and second cuneiform bones in an anteroposterior (AP) weight-bearing radiograph. This measure helps identify subtle injuries in which there is a proximal and medial subluxation of the first cuneiform-metatarsal complex. Delayed diagnosis and treatment have been associated with poorer results and significant functional consequences. This article describes a simple radiographic measurement to recognize the longitudinal injury pattern and to aid in determining whether operative intervention is required. PMID:25785475

  6. Longitudinal development of muons in large air showers studies from the arrival time distributions measured at 900m above sea level

    NASA Technical Reports Server (NTRS)

    Kakimoto, F.; Tsuchimoto, I.; Enoki, T.; Suga, K.; Nishi, K.

    1985-01-01

    The arrival time distributions of muons with energies above 1.0GeV and 0.5GeV have been measured in the Akeno air-shower array to study the longitudinal development of muons in air showers with primary energies in the range 10 to the 17th power to 10 to the 18th power ev. The average rise times of muons with energies above 1.0GeV at large core distances are consistent with those expected from very high multiplicity models and, on the contrary, with those expected from the low multiplicity models at small core distances. This implies that the longitudinal development at atmospheric depth smaller than 500 cm square is very fast and that at larger atmospheric depths is rather slow.

  7. Precision measurement of the longitudinal double-spin asymmetry for inclusive jet production in polarized proton collisions at √s = 200 GeV

    DOE PAGESBeta

    Adamczyk, L.

    2015-08-26

    We report a new measurement of the midrapidity inclusive jet longitudinal double-spin asymmetry, ALL, in polarized pp collisions at center-of-mass energy √s = 200 GeV. The STAR data place stringent constraints on polarized parton distribution functions extracted at next-to-leading order from global analyses of inclusive deep-inelastic scattering (DIS), semi-inclusive DIS, and RHIC pp data. Lastly, the measured asymmetries provide evidence at the 3σ level for positive gluon polarization in the Bjorken-x region x > 0.05 .

  8. Precision measurement of the longitudinal double-spin asymmetry for inclusive jet production in polarized proton collisions at √s = 200 GeV

    SciTech Connect

    Adamczyk, L.

    2015-08-26

    We report a new measurement of the midrapidity inclusive jet longitudinal double-spin asymmetry, ALL, in polarized pp collisions at center-of-mass energy √s = 200 GeV. The STAR data place stringent constraints on polarized parton distribution functions extracted at next-to-leading order from global analyses of inclusive deep-inelastic scattering (DIS), semi-inclusive DIS, and RHIC pp data. Lastly, the measured asymmetries provide evidence at the 3σ level for positive gluon polarization in the Bjorken-x region x > 0.05 .

  9. Precision Measurement of the Longitudinal Double-Spin Asymmetry for Inclusive Jet Production in Polarized Proton Collisions at √{s }=200 GeV

    NASA Astrophysics Data System (ADS)

    Adamczyk, L.; Adkins, J. K.; Agakishiev, G.; Aggarwal, M. M.; Ahammed, Z.; Alekseev, I.; Alford, J.; Anson, C. D.; Aparin, A.; Arkhipkin, D.; Aschenauer, E. C.; Averichev, G. S.; Banerjee, A.; Beavis, D. R.; Bellwied, R.; Bhasin, A.; Bhati, A. K.; Bhattarai, P.; Bichsel, H.; Bielcik, J.; Bielcikova, J.; Bland, L. C.; Bordyuzhin, I. G.; Borowski, W.; Bouchet, J.; Brandin, A. V.; Brovko, S. G.; Bültmann, S.; Bunzarov, I.; Burton, T. P.; Butterworth, J.; Caines, H.; Calderón de la Barca Sánchez, M.; Campbell, J. M.; Cebra, D.; Cendejas, R.; Cervantes, M. C.; Chaloupka, P.; Chang, Z.; Chattopadhyay, S.; Chen, H. F.; Chen, J. H.; Chen, L.; Cheng, J.; Cherney, M.; Chikanian, A.; Christie, W.; Chwastowski, J.; Codrington, M. J. M.; Contin, G.; Cramer, J. G.; Crawford, H. J.; Cudd, A. B.; Cui, X.; Das, S.; Davila Leyva, A.; De Silva, L. C.; Debbe, R. R.; Dedovich, T. G.; Deng, J.; Derevschikov, A. A.; Derradi de Souza, R.; Dhamija, S.; di Ruzza, B.; Didenko, L.; Dilks, C.; Ding, F.; Djawotho, P.; Dong, X.; Drachenberg, J. L.; Draper, J. E.; Du, C. M.; Dunkelberger, L. E.; Dunlop, J. C.; Efimov, L. G.; Engelage, J.; Engle, K. S.; Eppley, G.; Eun, L.; Evdokimov, O.; Eyser, O.; Fatemi, R.; Fazio, S.; Fedorisin, J.; Filip, P.; Finch, E.; Fisyak, Y.; Flores, C. E.; Gagliardi, C. A.; Gangadharan, D. R.; Garand, D.; Geurts, F.; Gibson, A.; Girard, M.; Gliske, S.; Greiner, L.; Grosnick, D.; Gunarathne, D. S.; Guo, Y.; Gupta, A.; Gupta, S.; Guryn, W.; Haag, B.; Hamed, A.; Han, L.-X.; Haque, R.; Harris, J. W.; Heppelmann, S.; Hirsch, A.; Hoffmann, G. W.; Hofman, D. J.; Horvat, S.; Huang, B.; Huang, H. Z.; Huang, X.; Huck, P.; Humanic, T. J.; Igo, G.; Jacobs, W. W.; Jang, H.; Judd, E. G.; Kabana, S.; Kalinkin, D.; Kang, K.; Kauder, K.; Ke, H. W.; Keane, D.; Kechechyan, A.; Kesich, A.; Khan, Z. H.; Kikola, D. P.; Kisel, I.; Kisiel, A.; Koetke, D. D.; Kollegger, T.; Konzer, J.; Koralt, I.; Kosarzewski, L. K.; Kotchenda, L.; Kraishan, A. F.; Kravtsov, P.; Krueger, K.; Kulakov, I.; Kumar, L.; Kycia, R. A.; Lamont, M. A. C.; Landgraf, J. M.; Landry, K. D.; Lauret, J.; Lebedev, A.; Lednicky, R.; Lee, J. H.; LeVine, M. J.; Li, C.; Li, W.; Li, X.; Li, X.; Li, Y.; Li, Z. M.; Lisa, M. A.; Liu, F.; Ljubicic, T.; Llope, W. J.; Lomnitz, M.; Longacre, R. S.; Luo, X.; Ma, G. L.; Ma, Y. G.; Madagodagettige Don, D. M. M. D.; Mahapatra, D. P.; Majka, R.; Margetis, S.; Markert, C.; Masui, H.; Matis, H. S.; McDonald, D.; McShane, T. S.; Minaev, N. G.; Mioduszewski, S.; Mohanty, B.; Mondal, M. M.; Morozov, D. A.; Mustafa, M. K.; Nandi, B. K.; Nasim, Md.; Nayak, T. K.; Nelson, J. M.; Nigmatkulov, G.; Nogach, L. V.; Noh, S. Y.; Novak, J.; Nurushev, S. B.; Odyniec, G.; Ogawa, A.; Oh, K.; Ohlson, A.; Okorokov, V.; Oldag, E. W.; Olvitt, D. L.; Pachr, M.; Page, B. S.; Pal, S. K.; Pan, Y. X.; Pandit, Y.; Panebratsev, Y.; Pawlak, T.; Pawlik, B.; Pei, H.; Perkins, C.; Peryt, W.; Pile, P.; Planinic, M.; Pluta, J.; Poljak, N.; Poniatowska, K.; Porter, J.; Poskanzer, A. M.; Pruthi, N. K.; Przybycien, M.; Pujahari, P. R.; Putschke, J.; Qiu, H.; Quintero, A.; Ramachandran, S.; Raniwala, R.; Raniwala, S.; Ray, R. L.; Riley, C. K.; Ritter, H. G.; Roberts, J. B.; Rogachevskiy, O. V.; Romero, J. L.; Ross, J. F.; Roy, A.; Ruan, L.; Rusnak, J.; Rusnakova, O.; Sahoo, N. R.; Sahu, P. K.; Sakrejda, I.; Salur, S.; Sandweiss, J.; Sangaline, E.; Sarkar, A.; Schambach, J.; Scharenberg, R. P.; Schmah, A. M.; Schmidke, W. B.; Schmitz, N.; Seger, J.; Seyboth, P.; Shah, N.; Shahaliev, E.; Shanmuganathan, P. V.; Shao, M.; Sharma, B.; Shen, W. Q.; Shi, S. S.; Shou, Q. Y.; Sichtermann, E. P.; Singaraju, R. N.; Skoby, M. J.; Smirnov, D.; Smirnov, N.; Solanki, D.; Sorensen, P.; Spinka, H. M.; Srivastava, B.; Stanislaus, T. D. S.; Stevens, J. R.; Stock, R.; Strikhanov, M.; Stringfellow, B.; Sumbera, M.; Sun, X.; Sun, X. M.; Sun, Y.; Sun, Z.; Surrow, B.; Svirida, D. N.; Symons, T. J. M.; Szelezniak, M. A.; Takahashi, J.; Tang, A. H.; Tang, Z.; Tarnowsky, T.; Thomas, J. H.; Timmins, A. R.; Tlusty, D.; Tokarev, M.; Trentalange, S.; Tribble, R. E.; Tribedy, P.; Trzeciak, B. A.; Tsai, O. D.; Turnau, J.; Ullrich, T.; Underwood, D. G.; Van Buren, G.; van Nieuwenhuizen, G.; Vandenbroucke, M.; Vanfossen, J. A.; Varma, R.; Vasconcelos, G. M. S.; Vasiliev, A. N.; Vertesi, R.; Videbæk, F.; Viyogi, Y. P.; Vokal, S.; Vossen, A.; Wada, M.; Wang, F.; Wang, G.; Wang, H.; Wang, J. S.; Wang, X. L.; Wang, Y.; Wang, Y.; Webb, G.; Webb, J. C.; Westfall, G. D.; Wieman, H.; Wissink, S. W.; Witt, R.; Wu, Y. F.; Xiao, Z.; Xie, W.; Xin, K.; Xu, H.; Xu, J.; Xu, N.; Xu, Q. H.; Xu, Y.; Xu, Z.; Yan, W.; Yang, C.; Yang, Y.; Yang, Y.; Ye, Z.; Yepes, P.; Yi, L.; Yip, K.; Yoo, I.-K.; Yu, N.; Zawisza, Y.; Zbroszczyk, H.; Zha, W.; Zhang, J. B.; Zhang, J. L.; Zhang, S.; Zhang, X. P.; Zhang, Y.; Zhang, Z. P.; Zhao, F.; Zhao, J.; Zhong, C.; Zhu, X.; Zhu, Y. H.; Zoulkarneeva, Y.; Zyzak, M.; STAR Collaboration

    2015-08-01

    We report a new measurement of the midrapidity inclusive jet longitudinal double-spin asymmetry, AL L, in polarized p p collisions at center-of-mass energy √{s }=200 GeV . The STAR data place stringent constraints on polarized parton distribution functions extracted at next-to-leading order from global analyses of inclusive deep-inelastic scattering (DIS), semi-inclusive DIS, and RHIC p p data. The measured asymmetries provide evidence at the 3 σ level for positive gluon polarization in the Bjorken-x region x >0.05 .

  10. Precision Measurement of the Longitudinal Double-Spin Asymmetry for Inclusive Jet Production in Polarized Proton Collisions at sqrt[s]=200  GeV.

    PubMed

    Adamczyk, L; Adkins, J K; Agakishiev, G; Aggarwal, M M; Ahammed, Z; Alekseev, I; Alford, J; Anson, C D; Aparin, A; Arkhipkin, D; Aschenauer, E C; Averichev, G S; Banerjee, A; Beavis, D R; Bellwied, R; Bhasin, A; Bhati, A K; Bhattarai, P; Bichsel, H; Bielcik, J; Bielcikova, J; Bland, L C; Bordyuzhin, I G; Borowski, W; Bouchet, J; Brandin, A V; Brovko, S G; Bültmann, S; Bunzarov, I; Burton, T P; Butterworth, J; Caines, H; Calderón de la Barca Sánchez, M; Campbell, J M; Cebra, D; Cendejas, R; Cervantes, M C; Chaloupka, P; Chang, Z; Chattopadhyay, S; Chen, H F; Chen, J H; Chen, L; Cheng, J; Cherney, M; Chikanian, A; Christie, W; Chwastowski, J; Codrington, M J M; Contin, G; Cramer, J G; Crawford, H J; Cudd, A B; Cui, X; Das, S; Davila Leyva, A; De Silva, L C; Debbe, R R; Dedovich, T G; Deng, J; Derevschikov, A A; Derradi de Souza, R; Dhamija, S; di Ruzza, B; Didenko, L; Dilks, C; Ding, F; Djawotho, P; Dong, X; Drachenberg, J L; Draper, J E; Du, C M; Dunkelberger, L E; Dunlop, J C; Efimov, L G; Engelage, J; Engle, K S; Eppley, G; Eun, L; Evdokimov, O; Eyser, O; Fatemi, R; Fazio, S; Fedorisin, J; Filip, P; Finch, E; Fisyak, Y; Flores, C E; Gagliardi, C A; Gangadharan, D R; Garand, D; Geurts, F; Gibson, A; Girard, M; Gliske, S; Greiner, L; Grosnick, D; Gunarathne, D S; Guo, Y; Gupta, A; Gupta, S; Guryn, W; Haag, B; Hamed, A; Han, L-X; Haque, R; Harris, J W; Heppelmann, S; Hirsch, A; Hoffmann, G W; Hofman, D J; Horvat, S; Huang, B; Huang, H Z; Huang, X; Huck, P; Humanic, T J; Igo, G; Jacobs, W W; Jang, H; Judd, E G; Kabana, S; Kalinkin, D; Kang, K; Kauder, K; Ke, H W; Keane, D; Kechechyan, A; Kesich, A; Khan, Z H; Kikola, D P; Kisel, I; Kisiel, A; Koetke, D D; Kollegger, T; Konzer, J; Koralt, I; Kosarzewski, L K; Kotchenda, L; Kraishan, A F; Kravtsov, P; Krueger, K; Kulakov, I; Kumar, L; Kycia, R A; Lamont, M A C; Landgraf, J M; Landry, K D; Lauret, J; Lebedev, A; Lednicky, R; Lee, J H; LeVine, M J; Li, C; Li, W; Li, X; Li, X; Li, Y; Li, Z M; Lisa, M A; Liu, F; Ljubicic, T; Llope, W J; Lomnitz, M; Longacre, R S; Luo, X; Ma, G L; Ma, Y G; Madagodagettige Don, D M M D; Mahapatra, D P; Majka, R; Margetis, S; Markert, C; Masui, H; Matis, H S; McDonald, D; McShane, T S; Minaev, N G; Mioduszewski, S; Mohanty, B; Mondal, M M; Morozov, D A; Mustafa, M K; Nandi, B K; Nasim, Md; Nayak, T K; Nelson, J M; Nigmatkulov, G; Nogach, L V; Noh, S Y; Novak, J; Nurushev, S B; Odyniec, G; Ogawa, A; Oh, K; Ohlson, A; Okorokov, V; Oldag, E W; Olvitt, D L; Pachr, M; Page, B S; Pal, S K; Pan, Y X; Pandit, Y; Panebratsev, Y; Pawlak, T; Pawlik, B; Pei, H; Perkins, C; Peryt, W; Pile, P; Planinic, M; Pluta, J; Poljak, N; Poniatowska, K; Porter, J; Poskanzer, A M; Pruthi, N K; Przybycien, M; Pujahari, P R; Putschke, J; Qiu, H; Quintero, A; Ramachandran, S; Raniwala, R; Raniwala, S; Ray, R L; Riley, C K; Ritter, H G; Roberts, J B; Rogachevskiy, O V; Romero, J L; Ross, J F; Roy, A; Ruan, L; Rusnak, J; Rusnakova, O; Sahoo, N R; Sahu, P K; Sakrejda, I; Salur, S; Sandweiss, J; Sangaline, E; Sarkar, A; Schambach, J; Scharenberg, R P; Schmah, A M; Schmidke, W B; Schmitz, N; Seger, J; Seyboth, P; Shah, N; Shahaliev, E; Shanmuganathan, P V; Shao, M; Sharma, B; Shen, W Q; Shi, S S; Shou, Q Y; Sichtermann, E P; Singaraju, R N; Skoby, M J; Smirnov, D; Smirnov, N; Solanki, D; Sorensen, P; Spinka, H M; Srivastava, B; Stanislaus, T D S; Stevens, J R; Stock, R; Strikhanov, M; Stringfellow, B; Sumbera, M; Sun, X; Sun, X M; Sun, Y; Sun, Z; Surrow, B; Svirida, D N; Symons, T J M; Szelezniak, M A; Takahashi, J; Tang, A H; Tang, Z; Tarnowsky, T; Thomas, J H; Timmins, A R; Tlusty, D; Tokarev, M; Trentalange, S; Tribble, R E; Tribedy, P; Trzeciak, B A; Tsai, O D; Turnau, J; Ullrich, T; Underwood, D G; Van Buren, G; van Nieuwenhuizen, G; Vandenbroucke, M; Vanfossen, J A; Varma, R; Vasconcelos, G M S; Vasiliev, A N; Vertesi, R; Videbæk, F; Viyogi, Y P; Vokal, S; Vossen, A; Wada, M; Wang, F; Wang, G; Wang, H; Wang, J S; Wang, X L; Wang, Y; Wang, Y; Webb, G; Webb, J C; Westfall, G D; Wieman, H; Wissink, S W; Witt, R; Wu, Y F; Xiao, Z; Xie, W; Xin, K; Xu, H; Xu, J; Xu, N; Xu, Q H; Xu, Y; Xu, Z; Yan, W; Yang, C; Yang, Y; Yang, Y; Ye, Z; Yepes, P; Yi, L; Yip, K; Yoo, I-K; Yu, N; Zawisza, Y; Zbroszczyk, H; Zha, W; Zhang, J B; Zhang, J L; Zhang, S; Zhang, X P; Zhang, Y; Zhang, Z P; Zhao, F; Zhao, J; Zhong, C; Zhu, X; Zhu, Y H; Zoulkarneeva, Y; Zyzak, M

    2015-08-28

    We report a new measurement of the midrapidity inclusive jet longitudinal double-spin asymmetry, A_{LL}, in polarized pp collisions at center-of-mass energy sqrt[s]=200  GeV. The STAR data place stringent constraints on polarized parton distribution functions extracted at next-to-leading order from global analyses of inclusive deep-inelastic scattering (DIS), semi-inclusive DIS, and RHIC pp data. The measured asymmetries provide evidence at the 3σ level for positive gluon polarization in the Bjorken-x region x>0.05. PMID:26371644

  11. The Alzheimer's Disease Cooperative Study Prevention Instrument Project: Longitudinal Outcome of Behavioral Measures as Predictors of Cognitive Decline

    PubMed Central

    Banks, Sarah Jane; Raman, Rema; He, Feng; Salmon, David P.; Ferris, Steven; Aisen, Paul; Cummings, Jeffrey

    2014-01-01

    Background/Methods The Alzheimer's Disease Cooperative Study Prevention Instrument Project is a longitudinal study that recruited 644 cognitively healthy older subjects (aged between 75 and 93 years, 58% women) at baseline and evaluated their cognitive change over 4 years. The study was structured like a clinical trial to anticipate a prevention trial and to determine the performance of novel trial instruments in a longitudinal non-interventional trial framework. Behavioral symptoms were assessed at baseline. Results The existence of participant-reported behavioral symptoms at baseline predicted conversion to Clinical Dementia Rating scale score ≥0.5 over the 4-year period. Conclusions The results imply that early anxiety and depression may be harbingers of future cognitive decline, and that patients exhibiting such symptoms, even in the absence of co-occurring cognitive symptoms, should be closely followed over time. PMID:25685141

  12. Measuring Executive Dysfunction Longitudinally and in Relation to Genetic Burden, Brain Volumetrics, and Depression in Prodromal Huntington Disease

    PubMed Central

    Papp, Kathryn V.; Snyder, Peter J.; Mills, James A.; Duff, Kevin; Westervelt, Holly J.; Long, Jeffrey D.; Lourens, Spencer; Paulsen, Jane S.

    2013-01-01

    Executive dysfunction (ED) is a characteristic of Huntington disease (HD), but its severity and progression is less understood in the prodromal phase, e.g., before gross motor abnormalities. We examined planning and problem-solving abilities using the Towers Task in HD mutation-positive individuals without motor symptoms (n = 781) and controls (n = 212). Participants with greater disease progression (determined using mutation size and current age) performed more slowly and with less accuracy on the Towers Task. Performance accuracy was negatively related to striatal volume while both accuracy and working memory were negatively related to frontal white matter volume. Disease progression at baseline was not associated with longitudinal performance over 4 years. Whereas the baseline findings indicate that ED becomes more prevalent with greater disease progression in prodromal HD and can be quantified using the Towers task, the absence of notable longitudinal findings indicates that the Towers Task exhibits limited sensitivity to cognitive decline in this population. PMID:23246934

  13. How Much Is Too Much? Multiple Measures in Practice.

    ERIC Educational Resources Information Center

    Hohn, Alisabeth M.; Veitch, William R.

    This paper describes the experiences of Colorado Springs School District Eleven in using multiple measures to determine if third graders were reading at "grade level." The use of multiple measures may be threatened by the rapidly increasing pressures about assessment and accountability in Colorado that teachers are beginning to feel that their…

  14. A Seminonparametric Approach to Joint Modeling of A Primary Binary Outcome and Longitudinal Data Measured at Discrete Informative Times

    PubMed Central

    Yan, Song; Zhang, Daowen; Lu, Wenbin; Grifo, James A.; Liu, Mengling

    2012-01-01

    In a study conducted at the New York University Fertility Center, one of the scientific objectives is to investigate the relationship between the final pregnancy outcomes of participants receiving an in vitro fertilization (IVF) treatment and their β-human chorionic gonadotrophin (β-hCG) profiles. A common joint modeling approach to this objective is to use subject-specific normal random effects in a linear mixed model for longitudinal β-hCG data as predictors in a model (e.g., logistic model) for the final pregnancy outcome. Empirical data exploration indicates that the observation times for longitudinal β-hCG data may be informative and the distribution of random effects for longitudinal β-hCG data may not be normally distributed. We propose to introduce a third model in the joint model for the informative β-hCG observation times, and relax the normality distributional assumption of random effects using the semi-nonparametric (SNP) approach of Gallant and Nychka (1987) [8]. An EM algorithm is developed for parameter estimation. Extensive simulation designed to evaluate the proposed method indicates that ignoring either informative observation times or distributional assumption of the random effects would lead to invalid and/or inefficient inference. Applying our new approach to the data reveals some interesting findings the traditional approach failed to discover. PMID:23259008

  15. Agreement between self-reported and measured height, weight and body mass index in old age—a longitudinal study with 20 years of follow-up

    PubMed Central

    Dahl, Anna K.; Hassing, Linda B.; Fransson, Eleonor I.; Pedersen, Nancy L.

    2010-01-01

    Background: self-reported body mass index (BMI) based on self-reported height and weight is a widely used measure of adiposity in epidemiological research. Knowledge about the accuracy of these measures in late life is scarce. Objective: the study aimed to evaluate the accuracy and changes in accuracy of self-reported height, weight and BMI calculated from self-reported height and weight in late life. Design: a longitudinal population-based study with five times of follow-up was conducted. Participants: seven hundred seventy-four community-living men and women, aged 40–88 at baseline (mean age 63.9), included in The Swedish Adoption/Twin Study of Aging. Methods: participants self-reported their height and weight in a questionnaire, and height and weight were measured by experienced research nurses at an in-person testing five times during a 20-year period. BMI was calculated as weight (kilogramme)/height (metre)2. Results: latent growth curve modelling showed an increase in the mean difference between self-reported and measured values over time for height (0.038 cm/year) and BMI (0.016 kg/m2/year), but not for weight. Conclusions: there is a very small increase in the mean difference between self-reported and measured BMI with ageing, which probably would not affect the results when self-reported BMI is used as a continuous variable in longitudinal studies. PMID:20453247

  16. Hospital process orientation from an operations management perspective: development of a measurement tool and practical testing in three ophthalmic practices

    PubMed Central

    2013-01-01

    Background Although research interest in hospital process orientation (HPO) is growing, the development of a measurement tool to assess process orientation (PO) has not been very successful yet. To view a hospital as a series of processes organized around patients with a similar demand seems to be an attractive proposition, but it is hard to operationalize this idea in a measurement tool that can actually measure the level of PO. This research contributes to HPO from an operations management (OM) perspective by addressing the alignment, integration and coordination of activities within patient care processes. The objective of this study was to develop and practically test a new measurement tool for assessing the degree of PO within hospitals using existing tools. Methods Through a literature search we identified a number of constructs to measure PO in hospital settings. These constructs were further operationalized, using an OM perspective. Based on five dimensions of an existing questionnaire a new HPO-measurement tool was developed to measure the degree of PO within hospitals on the basis of respondents’ perception. The HPO-measurement tool was pre-tested in a non-participating hospital and discussed with experts in a focus group. The multicentre exploratory case study was conducted in the ophthalmic practices of three different types of Dutch hospitals. In total 26 employees from three disciplines participated. After filling in the questionnaire an interview was held with each participant to check the validity and the reliability of the measurement tool. Results The application of the HPO-measurement tool, analysis of the scores and interviews with the participants resulted in the possibility to identify differences of PO performance and the areas of improvement – from a PO point of view – within each hospital. The result of refinement of the items of the measurement tool after practical testing is a set of 41 items to assess the degree of PO from an OM

  17. Theory and practice for measuring health care quality

    PubMed Central

    Berwick, Donald M.; Knapp, Marian Gilbert

    1987-01-01

    As competition, cost control, and new modes of delivery emerge in health care, there is a need to reexamine both the traditional definitions of health care quality and the methods by which it is measured. Industries other than health care have much to teach regarding the methods for obtaining, analyzing, and displaying data; techniques for problem identification, problem solving, and reassessment; and ideas about organizational factors that produce a high quality product or service. The Quality-of-Care Measurement Department at the Harvard Community Health Plan has built a program that draws from a distinguished health care quality assurance tradition and incorporates techniques that have been successful in other industries. PMID:10312319

  18. Putting Measurement First: Understanding "Grit" in Educational Policy and Practice

    ERIC Educational Resources Information Center

    Peterson, Daniel

    2015-01-01

    Non-cognitive dispositions have recently become psychological constructs of interest in the education, economics, philosophy, sociology, and psychology literature. In this article, I draw the distinction between property-first and measurement-first approaches to understanding the meaning of a particular non-cognitive disposition theoretical term,…

  19. MEASUREMENT OF HYDRAULIC CONDUCTIVITY DISTRIBUTIONS: A MANUAL OF PRACTICE

    EPA Science Inventory

    The ability of hydrologists to perform field measurements of aquifer hydraulic properties must be enhanced in order to significantly improve the capacity to solve groundwater contamination problems at Superfund and other sites. The primary purpose of this manual is to provide ne...

  20. MEASUREMENT OF HYDRAULIC CONDUCTIVITY DISTRIBUTIONS: A MANUAL OF PRACTICE

    EPA Science Inventory

    The ability of hydrologists to perform field measurements of aquifer hydraulic properties must be enhanced in order to significantly improve the capacity to solve groundwater contamination problems at Superfund and other sites. he primary purpose of this manual is to provide new ...

  1. ePortfolio as a Measure of Reflective Practice

    ERIC Educational Resources Information Center

    Parkes, Kelly A.; Dredger, Katie S.; Hicks, David

    2013-01-01

    This instructional article outlines the qualities of effective ePortfolios and how reflection and student growth is measured. Student exemplars and assessment rubrics show how, despite changing tools and evolving standards, sustained collaboration and student coaching yields reflective practitioners in content areas and in technological knowledge.…

  2. Measuring Motor Skill Learning--A Practical Application

    ERIC Educational Resources Information Center

    Kovacs, Christopher R.

    2008-01-01

    The assessment of fundamental motor skills in early learners is critical to the overall well-being and physical development of the students within the physical education setting. Olrich (2002) has suggested that any physical education program must be designed to assess both measures of physical fitness and fundamental motor skills in all students.…

  3. Comparison of Quality Oncology Practice Initiative (QOPI) Measure Adherence Between Oncology Fellows, Advanced Practice Providers, and Attending Physicians.

    PubMed

    Zhu, Jason; Zhang, Tian; Shah, Radhika; Kamal, Arif H; Kelley, Michael J

    2015-12-01

    Quality improvement measures are uniformly applied to all oncology providers, regardless of their roles. Little is known about differences in adherence to these measures between oncology fellows, advance practice providers (APP), and attending physicians. We investigated conformance across Quality Oncology Practice Initiative (QOPI) measures for oncology fellows, advance practice providers, and attending physicians at the Durham Veterans Affairs Medical Center (DVAMC). Using data collected from the Spring 2012 and 2013 QOPI cycles, we abstracted charts of patients and separated them based on their primary provider. Descriptive statistics and the chi-square test were calculated for each QOPI measure between fellows, advanced practice providers (APPs), and attending physicians. A total of 169 patients were reviewed. Of these, 31 patients had a fellow, 39 had an APP, and 99 had an attending as their primary oncology provider. Fellows and attending physicians performed similarly on 90 of 94 QOPI metrics. High-performing metrics included several core QOPI measures including documenting consent for chemotherapy, recommending adjuvant chemotherapy when appropriate, and prescribing serotonin antagonists when prescribing emetogenic chemotherapies. Low-performing metrics included documentation of treatment summary and taking action to address problems with emotional well-being by the second office visit. Attendings documented the plan for oral chemotherapy more often (92 vs. 63%, P=0.049). However, after the chart audit, we found that fellows actually documented the plan for oral chemotherapy 88% of the time (p=0.73). APPs and attendings performed similarly on 88 of 90 QOPI measures. The quality of oncology care tends to be similar between attendings and fellows overall; some of the significant differences do not remain significant after a second manual chart review, highlighting that the use of manual data collection for QOPI analysis is an imperfect system, and there may

  4. Measuring solar reflectance - Part II: Review of practical methods

    SciTech Connect

    Levinson, Ronnen; Akbari, Hashem; Berdahl, Paul

    2010-09-15

    A companion article explored how solar reflectance varies with surface orientation and solar position, and found that clear sky air mass 1 global horizontal (AM1GH) solar reflectance is a preferred quantity for estimating solar heat gain. In this study we show that AM1GH solar reflectance R{sub g,0} can be accurately measured with a pyranometer, a solar spectrophotometer, or an updated edition of the Solar Spectrum Reflectometer (version 6). Of primary concern are errors that result from variations in the spectral and angular distributions of incident sunlight. Neglecting shadow, background and instrument errors, the conventional pyranometer technique can measure R{sub g,0} to within 0.01 for surface slopes up to 5:12 [23 ], and to within 0.02 for surface slopes up to 12:12 [45 ]. An alternative pyranometer method minimizes shadow errors and can be used to measure R{sub g,0} of a surface as small as 1 m in diameter. The accuracy with which it can measure R{sub g,0} is otherwise comparable to that of the conventional pyranometer technique. A solar spectrophotometer can be used to determine R{sub g,0}{sup *}, a solar reflectance computed by averaging solar spectral reflectance weighted with AM1GH solar spectral irradiance. Neglecting instrument errors, R{sub g,0}{sup *} matches R{sub g,0} to within 0.006. The air mass 1.5 solar reflectance measured with version 5 of the Solar Spectrum Reflectometer can differ from R{sub g,0}{sup *} by as much as 0.08, but the AM1GH output of version 6 of this instrument matches R{sub g,0}{sup *} to within about 0.01. (author)

  5. Measuring solar reflectance Part II: Review of practical methods

    SciTech Connect

    Levinson, Ronnen; Akbari, Hashem; Berdahl, Paul

    2010-05-14

    A companion article explored how solar reflectance varies with surface orientation and solar position, and found that clear sky air mass 1 global horizontal (AM1GH) solar reflectance is a preferred quantity for estimating solar heat gain. In this study we show that AM1GH solar reflectance R{sub g,0} can be accurately measured with a pyranometer, a solar spectrophotometer, or an updated edition of the Solar Spectrum Reflectometer (version 6). Of primary concern are errors that result from variations in the spectral and angular distributions of incident sunlight. Neglecting shadow, background and instrument errors, the conventional pyranometer technique can measure R{sub g,0} to within 0.01 for surface slopes up to 5:12 [23{sup o}], and to within 0.02 for surface slopes up to 12:12 [45{sup o}]. An alternative pyranometer method minimizes shadow errors and can be used to measure R{sub g,0} of a surface as small as 1 m in diameter. The accuracy with which it can measure R{sub g,0} is otherwise comparable to that of the conventional pyranometer technique. A solar spectrophotometer can be used to determine R*{sub g,0}, a solar reflectance computed by averaging solar spectral reflectance weighted with AM1GH solar spectral irradiance. Neglecting instrument errors, R*{sub g,0} matches R{sub g,0} to within 0.006. The air mass 1.5 solar reflectance measured with version 5 of the Solar Spectrum Reflectometer can differ from R*{sub g,0} by as much as 0.08, but the AM1GH output of version 6 of this instrument matches R*{sub g,0} to within about 0.01.

  6. Outcome measures for palliative oxygen therapy: relevance and practical utility.

    PubMed

    Antoniu, Sabina; Mihaltan, Florin

    2014-06-01

    Dyspnea is a common symptom in many advanced malignant and non-malignant diseases and often is refractory to the usual therapies. In such circumstances palliative care approaches are necessary and among them palliative care oxygen therapy can be applied although currently its effectiveness is rather uncertain. Palliative oxygen therapy can be given on either continuous basis or on demand. Often the continuous palliative oxygen therapy is seen as long-term oxygen therapy although their aims are rather different. Palliative oxygen therapy was evaluated in populations with mixed underlying diseases, with outcome measures not only the most appropriate for the setting and therefore these limitations might have influenced the overall perceived therapeutic benefit. Therefore an evaluation of this method in subsets defined based on the etiology and pathogenic mechanisms and with appropriate outcome measures would help to better define the criteria for its indication and would increase its acceptability. PMID:24741999

  7. Modeling the longitudinal latent effect of pregabalin on self-reported changes in sleep disturbances in outpatients with generalized anxiety disorder managed in routine clinical practice

    PubMed Central

    Ruiz, Miguel A; Álvarez, Enrique; Carrasco, Jose L; Olivares, José M; Pérez, María; Rejas, Javier

    2015-01-01

    Background Anxiety disorders are among the most common psychiatric illnesses, with generalized anxiety disorder (GAD) being one of the most common. Sleep disturbances are highly prevalent in GAD patients. While treatment with pregabalin has been found to be associated with significant improvement in GAD-related sleep disturbance across many controlled clinical trials, mediational analysis has suggested that a substantial portion of this effect could be the result of a direct effect of pregabalin. Thus, the objective of this study was to model the longitudinal latent effect of pregabalin or usual care (UC) therapies on changes in sleep in outpatients with GAD under routine clinical practice. Methods Male and female GAD outpatients, aged 18 years or above, from a 6-month prospective noninterventional trial were analyzed. Direct and indirect effects of either pregabalin or UC changes in anxiety symptoms (assessed with Hamilton Anxiety Scale) and sleep disturbances (assessed with Medical Outcomes Study-Sleep Scale [MOS-S]) were estimated by a conditional latent curve model applying structural equation modeling. Results A total of 1,546 pregabalin-naïve patients were analyzed, 984 receiving pregabalin and 562 UC. Both symptoms of anxiety and sleep disturbances were significantly improved in both groups, with higher mean (95% confidence interval) score reductions in subjects receiving pregabalin: −15.9 (−15.2; −16.6) vs −14.5 (−13.5; −15.5), P=0.027, in Hamilton Anxiety Scale; and −29.7 (−28.1; −31.3) vs −24.0 (−21.6; −26.4), P<0.001, in MOS-S. The conditional latent curve model showed that the pregabalin effect on sleep disturbances was significant (γ =−3.99, P<0.001), after discounting the effect on reduction in anxiety symptoms. A mediation model showed that 70% of the direct effect of pregabalin on sleep remained after discounting the mediated effect of anxiety improvement. Conclusion A substantial proportion of the incremental

  8. Practical uncertainty reduction and quantification in shock physics measurements

    DOE PAGESBeta

    Akin, M. C.; Nguyen, J. H.

    2015-04-20

    We report the development of a simple error analysis sampling method for identifying intersections and inflection points to reduce total uncertainty in experimental data. This technique was used to reduce uncertainties in sound speed measurements by 80% over conventional methods. Here, we focused on its impact on a previously published set of Mo sound speed data and possible implications for phase transition and geophysical studies. However, this technique's application can be extended to a wide range of experimental data.

  9. Work engagement: a practical measure for workplace health promotion?

    PubMed

    Torp, S; Grimsmo, A; Hagen, S; Duran, A; Gudbergsson, S B

    2013-09-01

    The objectives of this study were to investigate whether psychological job demands, personal control and social support affect the negative health measure of depression differently than the positive measure of work engagement and to investigate whether work engagement mediates the effects of job demands and resources on the level of depression. We discuss the implications of using engagement as an outcome measure in workplace health promotion. We performed a cross-sectional questionnaire study among a general working population in Norway (n = 605). In the multivariate analysis, high psychological job demands as well as high control and social support correlated significantly with high work engagement. High demands as well as low control and social support correlated significantly with high levels of depression. When we included engagement as an independent variable together with demands, control and social support in the multivariate analysis, the positive correlation between demands and depression remained as well as the significant correlations between the level of depression and control and social support became non-significant. This indicates that engagement mediates the effects of control and social support on the level of depression. Encouraging enterprises to improve engagement in addition to focusing on preventing diseases may be worthwhile in workplace health promotion. Promoting engagement may have more positive organizational effects than a more traditional disease prevention focus, because engagement is contagious and closely related to good work performance and motivation. PMID:22692482

  10. The choice of self-rated health measures matter when predicting mortality: evidence from 10 years follow-up of the Australian longitudinal study of ageing

    PubMed Central

    2010-01-01

    Background Self-rated health (SRH) measures with different wording and reference points are often used as equivalent health indicators in public health surveys estimating health outcomes such as healthy life expectancies and mortality for older adults. Whilst the robust relationship between SRH and mortality is well established, it is not known how comparable different SRH items are in their relationship to mortality over time. We used a dynamic evaluation model to investigate the sensitivity of time-varying SRH measures with different reference points to predict mortality in older adults over time. Methods We used seven waves of data from the Australian Longitudinal Study of Ageing (1992 to 2004; N = 1733, 52.6% males). Cox regression analysis was used to evaluate the relationship between three time-varying SRH measures (global, age-comparative and self-comparative reference point) with mortality in older adults (65+ years). Results After accounting for other mortality risk factors, poor global SRH ratings increased mortality risk by 2.83 times compared to excellent ratings. In contrast, the mortality relationship with age-comparative and self-comparative SRH was moderated by age, revealing that these comparative SRH measures did not independently predict mortality for adults over 75 years of age in adjusted models. Conclusions We found that a global measure of SRH not referenced to age or self is the best predictor of mortality, and is the most reliable measure of self-perceived health for longitudinal research and population health estimates of healthy life expectancy in older adults. Findings emphasize that the SRH measures are not equivalent measures of health status. PMID:20403203

  11. How to measure soundscapes. A theoretical and practical approach

    NASA Astrophysics Data System (ADS)

    Schulte-Fortkamp, Brigitte

    2002-11-01

    Noise sources interact with the specific acoustic and environmental makeup, topography, meteorology, land use pattern, and lifestyle. The evaluation of soundscapes needs subject-related methodological procedures. With such suitable measurements a way has to be found that allows us to rely on different dimensions on reaction to noise. Improving the soundscape of an urban environment imposes to account for the qualitative appreciation as a cognitive judgment given by listeners and, particularly, for the interaction between acoustic dimensions and other sensory modalities in qualitative judgments of an urban environment (Maffiolo). The structure of the residential area that is, the combination of noise sources are important for the judgment of a soundscope and are also important as subjective parameters which are relevant in people's point of view. Moreover, the relationship of both define the background for assessments. Studies are needed on the subject and its capability in perception and interpretation; studies on the subject inside the society, studies on the social and cultural context, and field studies including physical measurements. Soundscapes may be defined in its effects on man and vice versa and probably acoustical ecology will serve to understand the function of soundscapes.

  12. Parental feeding practices in Mexican American families: Initial test of an expanded measure

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Although obesity rates are high among Latino children, relatively few studies of parental feeding practices have examined Latino families as a separate group. Culturally-based approaches to measurement development can begin to identify parental feeding practices in specific cultural groups. This stu...

  13. Practical Intelligence and Tacit Knowledge: Advancements in the Measurement of Developing Expertise

    ERIC Educational Resources Information Center

    Cianciolo, Anna T.; Grigorenko, Elena L.; Jarvin, Linda; Gil, Guillermo; Drebot, Michael E.; Sternberg, Robert J.

    2006-01-01

    Practical intelligence as measured by tacit-knowledge inventories generally has shown a weak relation to other intelligence constructs. However, the use of assessments capturing specialized, job-related knowledge may obscure the generality of practical intelligence and its relation to general intelligence. This article presents three studies in…

  14. Assessing the Validity of an Annual Survey for Measuring Principal Leadership Practice

    ERIC Educational Resources Information Center

    Camburn, Eric M.; Huff, Jason T.; Goldring, Ellen B.; May, Henry

    2010-01-01

    Because research has shown that principals' practices can significantly impact teaching and learning in their schools through multiple avenues, it is critical to understand the validity of tools that measure principal practice. While the field has relied heavily on self-report surveys, little is known about their validity. This study compares…

  15. US Physician Practices Spend More Than $15.4 Billion Annually To Report Quality Measures.

    PubMed

    Casalino, Lawrence P; Gans, David; Weber, Rachel; Cea, Meagan; Tuchovsky, Amber; Bishop, Tara F; Miranda, Yesenia; Frankel, Brittany A; Ziehler, Kristina B; Wong, Meghan M; Evenson, Todd B

    2016-03-01

    Each year US physician practices in four common specialties spend, on average, 785 hours per physician and more than $15.4 billion dealing with the reporting of quality measures. While much is to be gained from quality measurement, the current system is unnecessarily costly, and greater effort is needed to standardize measures and make them easier to report. PMID:26953292

  16. [Application of information technology in orthodontics. 3. Practical method for computer aided measurements of orthodontic models].

    PubMed

    Reinhardt, H; Haffner, T; Ifert, F; Malsch, J; Schneider, P

    1989-09-01

    A practical method for computer aided measurements of orthodontic models is introduced here. Measurements values are taken by using in incremental donor with the traditional slide rule. Advantages of this method lead to a higher efficiency of model measurements. PMID:2636504

  17. Grading Practice as Valid Measures of Academic Achievement of Secondary Schools Students for National Development

    ERIC Educational Resources Information Center

    Chiekem, Enwefa

    2015-01-01

    Assigning grades is probably the most important measurement decision that classroom teachers makes. When teachers are provided with some measurement instruction, they still use subjective value judgments when assigning grades to students. This paper therefore, examines the grading practice as valid measures of academic achievement in secondary…

  18. Physiological measurements of tissue health; implications for clinical practice.

    PubMed

    Kim, Jennifer H; Wang, Xiaofeng; Ho, Chester H; Bogie, Kath M

    2012-12-01

    Pressure mapping alone insufficiently describes tissue health. Comprehensive, quantitative non invasive assessment is crucial. Interface pressures (IPs) and transcutaneous blood gas levels [transcutaneous tissue oxygen (T(c) PO(2) )] were simultaneously assessed over both ischia and the sacrum to investigate the hypotheses: (i) tissue oxygenation decreases with sustained applied pressure; (ii) tissue oxygen and IP are inversely correlated in loaded soft tissues; (iii) multisite assessments are unnecessary because healthy individuals are symmetrical. Measurements were taken at 5-minute intervals for 20 minutes in both sitting and supine lying for a cohort of 20 able-bodied adults. There were no statistically significant changes over time for either variable in 96% of timepoint comparisons. Specifically, no significant differences were seen between 10 and 20 minutes in either position. These findings imply that a 10-minute assessment can reliably indicate tissue health and that tissue may adapt to applied load over time. No statistically significant correlations between T(c) PO(2) and IP were observed. However, the left and right ischia were significantly different for both variables in supine lying (P < 0.001) and for sitting IP (P < 0.010). Thus, even in this healthy cohort, postural symmetry was not observed and should not be assumed for other populations with restricted mobility. If a multisite technique cannot be used, repeated tissue health assessments must use the same anatomic location. PMID:22289151

  19. Access & Persistence: Findings from 10 Years of Longitudinal Research on Students. Informed Practice: Syntheses of Higher Education Research for Campus Leaders.

    ERIC Educational Resources Information Center

    Choy, Susan P.

    To answer questions about who goes to college, who persists toward a degree or credential, and what happens to students after they enroll, the National Center for Education Statistics conducted three national longitudinal studies to track students' through the postsecondary education system. These three surveys, the National Education Longitudinal…

  20. The Longitudinal Impact of a Universal School-Based Social-Emotional and Literacy Intervention on Classroom Climate and Teacher Processes and Practices

    ERIC Educational Resources Information Center

    Brown, Joshua L.; Jones, Stephanie M.; Aber, J. Lawrence

    2010-01-01

    This presentation capitalizes on a three-year, longitudinal, school-randomized trial of the 4Rs Program, a comprehensive, school-based social-emotional and literacy program for elementary schools, to test intervention induced changes in features of classroom climate and key dimensions of teacher affective and pedagogical processes and practices…

  1. Parenting Practices at 24 to 47 Months and IQ at Age 8: Effect-Measure Modification by Infant Temperament.

    PubMed

    Chong, Shiau Yun; Chittleborough, Catherine R; Gregory, Tess; Mittinty, Murthy N; Lynch, John W; Smithers, Lisa G

    2016-01-01

    Cognitive development might be influenced by parenting practices and child temperament. We examined whether the associations between parental warmth, control and intelligence quotient (IQ) may be heightened among children in difficult temperament. Participants were from the Avon Longitudinal Study of Parents and Children (n = 7,044). Temperament at 6 months was measured using the Revised Infant Temperament Questionnaire and classified into 'easy' and 'difficult'. Parental warmth and control was measured at 24 to 47 months and both were classified into 2 groups using latent class analyses. IQ was measured at 8 years using the Wechsler Intelligence Scale for Children and dichotomized (<85 and ≥85) for analyzing effect-measure modification by temperament. Linear regression adjusted for multiple confounders and temperament showed lower parental warmth was weakly associated with lower IQ score [β = -0.52 (95% CI 1.26, 0.21)], and higher parental control was associated with lower IQ score [β = -2.21 (-2.95, -1.48)]. Stratification by temperament showed no increased risk of having low IQ in temperamentally difficult children [risk ratio (RR) = 0.97 95% CI 0.65, 1.45)] but an increased risk among temperamentally easy children (RR = 1.12 95% CI 0.95, 1.32) when parental warmth was low. There was also no increased risk of having low IQ in temperamentally difficult children (RR = 1.02 95% CI 0.69, 1.53) but there was an increased risk among temperamentally easy children (RR = 1.30 95% CI 1.11, 1.53) when parental control was high. For both parental warmth and control, there was some evidence of negative effect-measure modification by temperament on the risk-difference scale and the risk-ratio scale. It may be more appropriate to provide parenting interventions as a universal program rather than targeting children with difficult temperament. PMID:27027637

  2. Parenting Practices at 24 to 47 Months and IQ at Age 8: Effect-Measure Modification by Infant Temperament

    PubMed Central

    Chong, Shiau Yun; Chittleborough, Catherine R.; Gregory, Tess; Mittinty, Murthy N.; Lynch, John W.; Smithers, Lisa G.

    2016-01-01

    Cognitive development might be influenced by parenting practices and child temperament. We examined whether the associations between parental warmth, control and intelligence quotient (IQ) may be heightened among children in difficult temperament. Participants were from the Avon Longitudinal Study of Parents and Children (n = 7,044). Temperament at 6 months was measured using the Revised Infant Temperament Questionnaire and classified into ‘easy’ and ‘difficult’. Parental warmth and control was measured at 24 to 47 months and both were classified into 2 groups using latent class analyses. IQ was measured at 8 years using the Wechsler Intelligence Scale for Children and dichotomized (<85 and ≥85) for analyzing effect-measure modification by temperament. Linear regression adjusted for multiple confounders and temperament showed lower parental warmth was weakly associated with lower IQ score [β = -0.52 (95% CI 1.26, 0.21)], and higher parental control was associated with lower IQ score [β = -2.21 (-2.95, -1.48)]. Stratification by temperament showed no increased risk of having low IQ in temperamentally difficult children [risk ratio (RR) = 0.97 95% CI 0.65, 1.45)] but an increased risk among temperamentally easy children (RR = 1.12 95% CI 0.95, 1.32) when parental warmth was low. There was also no increased risk of having low IQ in temperamentally difficult children (RR = 1.02 95% CI 0.69, 1.53) but there was an increased risk among temperamentally easy children (RR = 1.30 95% CI 1.11, 1.53) when parental control was high. For both parental warmth and control, there was some evidence of negative effect-measure modification by temperament on the risk-difference scale and the risk-ratio scale. It may be more appropriate to provide parenting interventions as a universal program rather than targeting children with difficult temperament. PMID:27027637

  3. Recommended Practice for Pressure Measurements and Calculation of Effective Pumping Speeds During Electric Propulsion Testing

    NASA Technical Reports Server (NTRS)

    Dankanich, John W.; Walker, Mitchell; Swiatek, Michael W.; Yim, John T.

    2013-01-01

    The electric propulsion community has been implored to establish and implement a set of universally applicable test standards during the research, development, and qualification of electric propulsion systems. Variability between facility-to-facility and more importantly ground-to-flight performance can result in large margins in application or aversion to mission infusion. Performance measurements and life testing under appropriate conditions can be costly and lengthy. Measurement practices must be consistent, accurate, and repeatable. Additionally, the measurements must be universally transportable across facilities throughout the development, qualification, spacecraft integration, and on-orbit performance. A recommended practice for making pressure measurements, pressure diagnostics, and calculating effective pumping speeds with justification is presented.

  4. Longitudinal study of infectious intestinal disease in the UK (IID2 study): incidence in the community and presenting to general practice

    PubMed Central

    Rodrigues, Laura C; Viviani, Laura; Dodds, Julie P; Evans, Meirion R; Hunter, Paul R; Gray, Jim J; Letley, Louise H; Rait, Greta; Tompkins, David S; O'Brien, Sarah J

    2011-01-01

    Objectives To estimate, overall and by organism, the incidence of infectious intestinal disease (IID) in the community, presenting to general practice (GP) and reported to national surveillance. Design Prospective, community cohort study and prospective study of GP presentation conducted between April 2008 and August 2009. Setting Eighty-eight GPs across the UK recruited from the Medical Research Council General Practice Research Framework and the Primary Care Research Networks. Participants 6836 participants registered with the 88 participating practices in the community study; 991 patients with UK-acquired IID presenting to one of 37 practices taking part in the GP presentation study. Main outcome measures IID rates in the community, presenting to GP and reported to national surveillance, overall and by organism; annual IID cases and GP consultations by organism. Results The overall rate of IID in the community was 274 cases per 1000 person-years (95% CI 254 to 296); the rate of GP consultations was 17.7 per 1000 person-years (95% CI 14.4 to 21.8). There were 147 community cases and 10 GP consultations for every case reported to national surveillance. Norovirus was the most common organism, with incidence rates of 47 community cases per 1000 person-years and 2.1 GP consultations per 1000 person-years. Campylobacter was the most common bacterial pathogen, with a rate of 9.3 cases per 1000 person-years in the community, and 1.3 GP consultations per 1000 person-years. We estimate that there are up to 17 million sporadic, community cases of IID and 1 million GP consultations annually in the UK. Of these, norovirus accounts for 3 million cases and 130 000 GP consultations, and Campylobacter is responsible for 500 000 cases and 80 000 GP consultations. Conclusions IID poses a substantial community and healthcare burden in the UK. Control efforts must focus particularly on reducing the burden due to Campylobacter and enteric viruses. PMID:21708822

  5. Do "High-Performance" Work Practices Improve Establishment-Level Outcomes?

    ERIC Educational Resources Information Center

    Cappelli, Peter; Neumark, David

    2001-01-01

    Links between organizational performance and high-performance work practices were studied using data from the National Employment Survey, measures of work practices comparable across organizations, and a longitudinal design incorporating data predating use of high-performance practices. Practices raise employee compensation without necessarily…

  6. Brain Tumor Therapy-Induced Changes in Normal-Appearing Brainstem Measured With Longitudinal Diffusion Tensor Imaging

    SciTech Connect

    Hua Chiaho; Merchant, Thomas E.; Gajjar, Amar; Broniscer, Alberto; Zhang, Yong; Li Yimei; Glenn, George R.; Kun, Larry E.; Ogg, Robert J.

    2012-04-01

    Purpose: To characterize therapy-induced changes in normal-appearing brainstems of childhood brain tumor patients by serial diffusion tensor imaging (DTI). Methods and Materials: We analyzed 109 DTI studies from 20 brain tumor patients, aged 4 to 23 years, with normal-appearing brainstems included in the treatment fields. Those with medulloblastomas, supratentorial primitive neuroectodermal tumors, and atypical teratoid rhabdoid tumors (n = 10) received postoperative craniospinal irradiation (23.4-39.6 Gy) and a cumulative dose of 55.8 Gy to the primary site, followed by four cycles of high-dose chemotherapy. Patients with high-grade gliomas (n = 10) received erlotinib during and after irradiation (54-59.4 Gy). Parametric maps of fractional anisotropy (FA) and apparent diffusion coefficient (ADC) were computed and spatially registered to three-dimensional radiation dose data. Volumes of interest included corticospinal tracts, medial lemnisci, and the pons. Serving as an age-related benchmark for comparison, 37 DTI studies from 20 healthy volunteers, aged 6 to 25 years, were included in the analysis. Results: The median DTI follow-up time was 3.5 years (range, 1.6-5.0 years). The median mean dose to the pons was 56 Gy (range, 7-59 Gy). Three patterns were seen in longitudinal FA and apparent diffusion coefficient changes: (1) a stable or normal developing time trend, (2) initial deviation from normal with subsequent recovery, and (3) progressive deviation without evidence of complete recovery. The maximal decline in FA often occurred 1.5 to 3.5 years after the start of radiation therapy. A full recovery time trend could be observed within 4 years. Patients with incomplete recovery often had a larger decline in FA within the first year. Radiation dose alone did not predict long-term recovery patterns. Conclusions: Variations existed among individual patients after therapy in longitudinal evolution of brainstem white matter injury and recovery. Early response in

  7. Flip-angle profile of slice-selective excitation and the measurement of the MR longitudinal relaxation time with steady-state magnetization.

    PubMed

    Hsu, Jung-Jiin

    2015-08-01

    In MRI, the flip angle (FA) of slice-selective excitation is not uniform across the slice-thickness dimension. This work investigates the effect of the non-uniform FA profile on the accuracy of a commonly-used method for the measurement, in which the T1 value, i.e., the longitudinal relaxation time, is determined from the steady-state signals of an equally-spaced RF pulse train. By using the numerical solutions of the Bloch equation, it is shown that, because of the non-uniform FA profile, the outcome of the T1 measurement depends significantly on T1 of the specimen and on the FA and the inter-pulse spacing τ of the pulse train. A new method to restore the accuracy of the T1 measurement is described. Different from the existing approaches, the new method also removes the FA profile effect for the measurement of the FA, which is normally a part of the T1 measurement. In addition, the new method does not involve theoretical modeling, approximation, or modification to the underlying principle of the T1 measurement. An imaging experiment is performed, which shows that the new method can remove the FA-, the τ-, and the T1-dependence and produce T1 measurements in excellent agreement with the ones obtained from a gold standard method (the inversion-recovery method). PMID:26159799

  8. Flip-angle profile of slice-selective excitation and the measurement of the MR longitudinal relaxation time with steady-state magnetization

    NASA Astrophysics Data System (ADS)

    Hsu, Jung-Jiin

    2015-08-01

    In MRI, the flip angle (FA) of slice-selective excitation is not uniform across the slice-thickness dimension. This work investigates the effect of the non-uniform FA profile on the accuracy of a commonly-used method for the measurement, in which the T1 value, i.e., the longitudinal relaxation time, is determined from the steady-state signals of an equally-spaced RF pulse train. By using the numerical solutions of the Bloch equation, it is shown that, because of the non-uniform FA profile, the outcome of the T1 measurement depends significantly on T1 of the specimen and on the FA and the inter-pulse spacing τ of the pulse train. A new method to restore the accuracy of the T1 measurement is described. Different from the existing approaches, the new method also removes the FA profile effect for the measurement of the FA, which is normally a part of the T1 measurement. In addition, the new method does not involve theoretical modeling, approximation, or modification to the underlying principle of the T1 measurement. An imaging experiment is performed, which shows that the new method can remove the FA-, the τ-, and the T1-dependence and produce T1 measurements in excellent agreement with the ones obtained from a gold standard method (the inversion-recovery method).

  9. Multilevel assessment of immunisation uptake as a performance measure in general practice.

    PubMed Central

    Jones, K; Moon, G

    1991-01-01

    OBJECTIVE--To provide a measure of general practitioners' performance regarding uptake of immunisation against pertussis, taking account of the impact of patient characteristics on levels of uptake. DESIGN--Multilevel model of immunisation status against six measures of patient characteristics (level 1 predictor variables) with practice constraints as level 2 variables. SETTING--126 practices in southern England. SUBJECTS--2048 infants identified from infant surveillance and immunisation records. MAIN OUTCOME MEASURES--Top 10 practices with respect to uptake of pertussis immunisation according to a "null" model (model A) and according to a model that included six level 1 variables (model B); differences in ranking between the two models. RESULTS--Practices with low numbers of infants' requiring immunisation had imprecise and unstable uptake rates (range 0%-100%). With the multilevel procedure, after controlling for patient characteristics, practices in suburban catchment areas comprised largely of mature or young professionals performed best. Most improved performances when patient characteristics were taken into account were in practices in areas with a stable population and local authority housing--one such practice improved its ranking by 47 places. CONCLUSIONS--Crude uptake rates are inadequate performance indicators. Alternative approaches suggest that praiseworthy efforts to raise immunisation rates in unpromising areas are unrewarded by simple target based assessments. PMID:1859953

  10. Flight Measurements to Determine Effect of a Spring-Loaded Tab on Longitudinal Stability of an Airplane

    NASA Technical Reports Server (NTRS)

    Hunter, Paul A.; Reeder, John P.

    1946-01-01

    In conjunction with a program of research on the general problem of stability of airplanes in the climbing condition, tests have been made of a spring-loaded tb which. is referred to as a ?springy tab,? installed on the elevator of a low-wing scout bomber. The tab was arranged to deflect upward with decrease in speed which caused an increase in the pull force required to trim at low speeds and thereby increased the stick-free static longitudinal stability of the airplane. It was found that the springy tab would increase the stick-free stability in all flight conditions, would reduce the danger of inadvertent stalling because of the definite pull force required to stall the airplane with power on, would reduce the effect of center-of-gravity position on stick-free static stability, and would have little effect on the elevator stick forces in accelerated f11ght. Another advantage of the springy tab is that it might be used to provide almost any desired variation of elevator stick force with speed by adjusting the tab hinge-moment characteristics and the variation of spring moment with tab deflection. Unlike the bungee and the bobweight, the springy tab would provide stick-free static stability without requiring a pull force to hold the stick back while taxying. A device similar to the springy tab may be used on the rudder or ailerons to eliminate undesirable trim-force variations with speed.

  11. The Development of a Practical and Reliable Assessment Measure for Atopic Dermatitis (ADAM).

    ERIC Educational Resources Information Center

    Charman, Denise; Varigos, George; Horne, David J. de L.; Oberklaid, Frank

    1999-01-01

    A study was conducted in Australia to develop a reliable, valid, and practical measure of atopic dermatitis. The test development process and validity evaluation with two doctors and 51 patients are discussed. Results suggest that operational definitions of the scales need to be defined more clearly. The measure satisfies assumptions for a partial…

  12. Measuring the Quality of Inclusive Practices: Findings from the Inclusive Classroom Profile Pilot

    ERIC Educational Resources Information Center

    Soukakou, Elena P.; Winton, Pam J.; West, Tracey A.; Sideris, John H.; Rucker, Lia M.

    2014-01-01

    The purpose of this study was to test the reliability and validity of the Inclusive Classroom Profile (ICP), an observation measure designed to assess the quality of classroom practices in inclusive preschool programs. The measure was field tested in 51 inclusive classrooms. Results confirmed and extended previous research findings, providing…

  13. Longitudinally Jointed Edge-Wise Compression HoneyComb Composite Sandwich Coupon Testing And Fe Analysis: Three Methods of Strain Measurement, And Comparison

    NASA Technical Reports Server (NTRS)

    Farrokh, Babak; Rahim, Nur Aida Abul; Segal, Ken; Fan, Terry; Jones, Justin; Hodges, Ken; Mashni, Noah; Garg, Naman; Sang, Alex

    2013-01-01

    Three distinct strain measurement methods (i.e., foil resistance strain gages, fiber optic strain sensors, and a three-dimensional digital image photogrammetry that gives full field strain and displacement measurements) were implemented to measure strains on the back and front surfaces of a longitudinally jointed curved test article subjected to edge-wise compression testing, at NASA Goddard Space Flight Center, according to ASTM C364. The pre-test finite element analysis (FEA) was conducted to assess ultimate failure load and predict strain distribution pattern throughout the test coupon. The predicted strain pattern contours were then utilized as guidelines for installing the strain measurement instrumentations. The foil resistance strain gages and fiber optic strain sensors were bonded on the specimen at locations with nearly the same analytically predicted strain values, and as close as possible to each other, so that, comparisons between the measured strains by strain gages and fiber optic sensors, as well as the three-dimensional digital image photogrammetric system are relevant. The test article was loaded to failure (at 167 kN), at the compressive strain value of 10,000 micro epsilon. As a part of this study, the validity of the measured strains by fiber optic sensors is examined against the foil resistance strain gages and the three-dimensional digital image photogrammetric data, and comprehensive comparisons are made with FEA predictions.

  14. A Review of Psychometric Assessment and Reporting Practices: An Examination of Measurement-Oriented versus Non-Measurement-Oriented Domains

    ERIC Educational Resources Information Center

    Slaney, Kathleen L.; Tkatchouk, Masha; Gabriel, Stephanie M.; Ferguson, Leona P.; Knudsen, Jared R. S.; Legere, Julien C.

    2010-01-01

    The primary aim of the present study is to determine whether the psychometric evaluation practices and test-analytic rationales of researchers publishing in journals with a measurement focus differ from those of researchers publishing in journals with varying substantive research foci. Several components of two different samples of articles were…

  15. Practice.

    PubMed

    Chambers, David W

    2008-01-01

    Practice refers to a characteristic way professionals use common standards to customize solutions to a range of problems. Practice includes (a) standards for outcomes and processes that are shared with one's colleagues, (b) a rich repertoire of skills grounded in diagnostic acumen, (c) an ability to see the actual and the ideal and work back and forth between them, (d) functional artistry, and (e) learning by doing that transcends scientific rationality. Communities of practice, such as dental offices, are small groups that work together in interlocking roles to achieve these ends. PMID:19413050

  16. Parental feeding practices in Mexican American families: initial test of an expanded measure

    PubMed Central

    2013-01-01

    Background Although obesity rates are high among Latino children, relatively few studies of parental feeding practices have examined Latino families as a separate group. Culturally-based approaches to measurement development can begin to identify parental feeding practices in specific cultural groups. This study used qualitative and quantitative methods to develop and test the Parental Feeding Practices (PFP) Questionnaire for use with Mexican American parents. Items reflected both parent’s use of control over child eating and child-centered feeding practices. Methods In the qualitative phase of the research, 35 Latino parents participated in focus groups. Items for the PFP were developed from focus group discussions, as well as adapted from existing parent feeding practice measures. Cognitive interviews were conducted with 37 adults to evaluate items. In the quantitative phase, mothers and fathers of 174 Mexican American children ages 8–10 completed the PFP and provided demographic information. Anthropometric measures were obtained on family members. Results Confirmatory factor analyses identified four parental feeding practice dimensions: positive involvement in child eating, pressure to eat, use of food to control behavior, and restriction of amount of food. Factorial invariance modeling suggested equivalent factor meaning and item response scaling across mothers and fathers. Mothers and fathers differed somewhat in their use of feeding practices. All four feeding practices were related to child body mass index (BMI) percentiles, for one or both parents. Mothers reporting more positive involvement had children with lower BMI percentiles. Parents using more pressure to eat had children with lower BMI percentiles, while parents using more restriction had children with higher BMI percentiles. Fathers using food to control behavior had children with lower BMI percentiles. Conclusions Results indicate good initial validity and reliability for the PFP. It can be

  17. Validation of an instrument to measure inter-organisational linkages in general practice

    PubMed Central

    Amoroso, Cheryl; Proudfoot, Judith; Bubner, Tanya; Jayasinghe, Upali W.; Holton, Christine; Winstanley, Julie; Beilby, Justin; Harris, Mark F.

    2007-01-01

    Purpose Linkages between general medical practices and external services are important for high quality chronic disease care. The purpose of this research is to describe the development, evaluation and use of a brief tool that measures the comprehensiveness and quality of a general practice's linkages with external providers for the management of patients with chronic disease. In this study, clinical linkages are defined as the communication, support, and referral arrangements between services for the care and assistance of patients with chronic disease. Methods An interview to measure surgery-level (rather than individual clinician-level) clinical linkages was developed, piloted, reviewed, and evaluated with 97 Australian general practices. Two validated survey instruments were posted to patients, and a survey of locally available services was developed and posted to participating Divisions of General Practice (support organisations). Hypotheses regarding internal validity, association with local services, and patient satisfaction were tested using factor analysis, logistic regression and multilevel regression models. Results The resulting General Practice Clinical Linkages Interview (GP-CLI) is a nine-item tool with three underlying factors: referral and advice linkages, shared care and care planning linkages, and community access and awareness linkages. Local availability of chronic disease services has no affect on the comprehensiveness of services with which practices link, however, comprehensiveness of clinical linkages has an association with patient assessment of access, receptionist services, and of continuity of care in their general practice. Conclusions The GP-CLI may be useful to researchers examining comparable health care systems for measuring the comprehensiveness and quality of linkages at a general practice-level with related services, possessing both internal and external validity. The tool can be used with large samples exploring the impact

  18. Detection of DC currents and resistance measurements in longitudinal spin Seebeck effect experiments on Pt/YIG and Pt/NFO

    NASA Astrophysics Data System (ADS)

    Meier, Daniel; Kuschel, Timo; Meyer, Sibylle; Goennenwein, Sebastian T. B.; Shen, Liming; Gupta, Arunava; Schmalhorst, Jan-Michael; Reiss, Günter

    2016-05-01

    In this work we investigated thin films of the ferrimagnetic insulators Y 3Fe5O12 and NiFe2O4 capped with thin Pt layers in terms of the longitudinal spin Seebeck effect (LSSE). The electric response detected in the Pt layer under an out-of-plane temperature gradient can be interpreted as a pure spin current converted into a charge current via the inverse spin Hall effect. Typically, the transverse voltage is the quantity investigated in LSSE measurements (in the range of μV). Here, we present the directly detected DC current (in the range of nA) as an alternative quantity. Furthermore, we investigate the resistance of the Pt layer in the LSSE configuration. We found an influence of the test current on the resistance. The typical shape of the LSSE curve varies for increasing test currents.

  19. Measuring accuracy of sphygmomanometers in the medical practices of Swiss primary care physicians

    PubMed Central

    2013-01-01

    Objective Arterial hypertension has a high prevalence in most countries. Blood pressure measurements are performed frequently by primary care physicians. Recommendations from different societies emphasise the importance of measuring blood pressure with well maintained and calibrated instruments only. Since appropriate quality control measures are lacking the following survey was conducted in the medical practices of Swiss primary care physicians. Methods This is a cross-sectional survey with Swiss primary care physicians. Nine hundred and seventy-five sphygmomanometers used in the daily practice of medicine were compared and calibrated against a certified calibrator. The magnitude of the measuring error before and after calibration was determined. Results The proportion of the instruments that measured within the required tolerance of ± 3 mmHg over all measuring ranges was 81.4%. The average maintenance time was 5.6 years (± 3.8), and 97% (n = 353) of these instruments had not been maintained for two years (i.e. the recommended maintenance interval) or more. Two years after maintenance the number of devices with measurement errors of more than ± 3 mmHg increased significantly. Conclusion In Swiss primary care practices, the majority of upper arm and wrist sphygmomanometers measured blood pressure within a tolerance of ± 3 mmHg despite low adherence to the recommended maintenance interval. Two years after maintenance the number of sphygmomanometers with measurement errors increased significantly. PMID:23822652

  20. Effect of mailed feedback on drug prescribing profiles in general practice: a seven-year longitudinal study in Storstrøm County, Denmark

    PubMed Central

    2010-01-01

    Background Whether written feedback on drug prescribing in general practice affects prescribing habits is controversial. Most short-term studies showed no effect. However, the issue has not been tested in long-term studies involving the local general practitioner community. Aims of the study To assess whether prescribing levels in general practice are affected by long-term, unsolicited, systematically repeated, mailed feedback. Methods Each of the 94 general practices in Storstrøm County, Denmark, received semi-annual, mailed feedback about their prescribing volumes and costs within 13 major drug groups, in relation to the levels for all the other 93 practices over a 7-year period in a project initiated by the local general practitioner association. Data on the number of defined daily doses (DDDs) prescribed per 1000 listed patients in each practice per 6-months, and practice characteristics, were obtained from the Pharmaceutical Database at the County Health Department. Results There was a large variation in drug prescribing volume between practices, but little within-practice variation over time. After adjustments for the influence of practice size and other potential outcome-affecting variables, there was no evidence of a general change of prescribing volume over time, no change among practices with a high or a low prescribing level, and no significant change within the various drug groups. Conclusions We found no significant effects on prescribing levels of mailed feedback, even when repeated semi-annually during 7 years and initiated by the local general practitioner community. PMID:20929310

  1. Facilitating comfort for hospitalized patients using non-pharmacological measures: preliminary development of clinical practice guidelines.

    PubMed

    Williams, Anne M; Davies, Anne; Griffiths, Gareth

    2009-06-01

    Nurses often use non-pharmacological measures to facilitate comfort for patients within the hospital setting. However, guidelines for use of these measures are commonly inadequate or absent. This paper presents 12 clinical practice guidelines that were developed from the findings of a literature review into non-pharmacological measures that are thought to facilitate patient comfort. The non-pharmacological measures addressed in these guidelines are: Aromotherapy, Distraction, Guided Imagery, Laughter, Massage, Music, Reiki, Heat or Cold, Meditation, Reflexology, Reposition and Transcutaneous Electrical Nerve Stimulation. These are preliminary guidelines for the use of non-pharmacological measures and further research and development of such guidelines is recommended. PMID:19531072

  2. Comparison of Longitudinal In Vivo Measurements of Retinal Nerve Fiber Layer Thickness and Retinal Ganglion Cell Density after Optic Nerve Transection in Rat

    PubMed Central

    Choe, Tiffany E.; Abbott, Carla J.; Piper, Chelsea; Wang, Lin; Fortune, Brad

    2014-01-01

    Purpose To determine the relationship between longitudinal in vivo measurements of retinal nerve fiber layer thickness (RNFLT) and retinal ganglion cell (RGC) density after unilateral optic nerve transection (ONT). Methods Nineteen adult Brown-Norway rats were studied; N = 10 ONT plus RGC label, N = 3 ONT plus vehicle only (sans label), N = 6 sham ONT plus RGC label. RNFLT was measured by spectral domain optical coherence tomography (SD-OCT) at baseline then weekly for 1 month. RGCs were labeled by retrograde transport of fluorescently conjugated cholera toxin B (CTB) from the superior colliculus 48 hours prior to ONT or sham surgery. RGC density measurements were obtained by confocal scanning laser ophthalmoscopy (CSLO) at baseline and weekly for 1 month. RGC density and reactivity of microglia (anti-Iba1) and astrocytes (anti-GFAP) were determined from post mortem fluorescence microscopy of whole-mount retinae. Results RNFLT decreased after ONT by 17% (p<0.05), 30% (p<0.0001) and 36% (p<0.0001) at weeks 2, 3 and 4. RGC density decreased after ONT by 18%, 69%, 85% and 92% at weeks 1, 2, 3 and 4 (p<0.0001 each). RGC density measured in vivo at week 4 and post mortem by microscopy were strongly correlated (R = 0.91, p<0.0001). In vivo measures of RNFLT and RGC density were strongly correlated (R = 0.81, p<0.0001). In ONT- CTB labeled fellow eyes, RNFLT increased by 18%, 52% and 36% at weeks 2, 3 and 4 (p<0.0001), but did not change in fellow ONT-eyes sans CTB. Microgliosis was evident in the RNFL of the ONT-CTB fellow eyes, exceeding that observed in other fellow eyes. Conclusions In vivo measurements of RNFLT and RGC density are strongly correlated and can be used to monitor longitudinal changes after optic nerve injury. The strong fellow eye effect observed in eyes contralateral to ONT, only in the presence of CTB label, consisted of a dramatic increase in RNFLT associated with retinal microgliosis. PMID:25393294

  3. Feedback from Outcome Measures and Treatment Effectiveness, Treatment Efficiency, and Collaborative Practice: A Systematic Review.

    PubMed

    Gondek, Dawid; Edbrooke-Childs, Julian; Fink, Elian; Deighton, Jessica; Wolpert, Miranda

    2016-05-01

    Due to recent increases in the use of feedback from outcome measures in mental health settings, we systematically reviewed evidence regarding the impact of feedback from outcome measures on treatment effectiveness, treatment efficiency, and collaborative practice. In over half of 32 studies reviewed, the feedback condition had significantly higher levels of treatment effectiveness on at least one treatment outcome variable. Feedback was particularly effective for not-on-track patients or when it was provided to both clinicians and patients. The findings for treatment efficiency and collaborative practice were less consistent. Given the heterogeneity of studies, more research is needed to determine when and for whom feedback is most effective. PMID:26744316

  4. Longitudinally Jointed Edge-wise Compression Honeycomb Composite Sandwich Coupon Testing and FE Analysis: Three Methods of Strain Measurement, and Comparison

    NASA Technical Reports Server (NTRS)

    Farrokh, Babak; AbdulRahim, Nur Aida; Segal, Ken; Fan, Terry; Jones, Justin; Hodges, Ken; Mashni, Noah; Garg, Naman; Sang, Alex; Gifford, Dawn; Froggatt, Mark

    2013-01-01

    Three means (i.e., typical foil strain gages, fiber optic sensors, and a digital image correlation (DIC) system) were implemented to measure strains on the back and front surfaces of a longitudinally jointed curved test article subjected to edge-wise compression testing, at NASA Goddard Space Flight Center, according to ASTM C364. The Pre-test finite element analysis (FEA) was conducted to assess ultimate failure load and predict strain distribution pattern throughout the test coupon. The predicted strain pattern contours were then utilized as guidelines for installing the strain measurement instrumentations. The strain gages and fiber optic sensors were bonded on the specimen at locations with nearly the same strain values, as close as possible to each other, so that, comparisons between the measured strains by strain gages and fiber optic sensors, as well as the DIC system are justified. The test article was loaded to failure (at approximately 38 kips), at the strain value of approximately 10,000mu epsilon As a part of this study, the validity of the measured strains by fiber optic sensors is examined against the strain gage and DIC data, and also will be compared with FEA predictions.

  5. Constancy of Adult Personality Structure in Males: Longitudinal, Cross-Sectional and Times-of-Measurement Analyses.

    ERIC Educational Resources Information Center

    McCrae, Robert R.; And Others

    1980-01-01

    The invariance of factor structures in the Guilford Zimmerman Temperament Survey is clearly evident. Basic personality structure appears little affected by social and historical change. Results favor the stability model for objectively measured personality traits in adult males. (JAC)

  6. Relation between night visit rates and deprivation measures in one general practice.

    PubMed Central

    Carlisle, R D; Johnstone, S P; Pearson, J C

    1993-01-01

    OBJECTIVE--To compare night visit rates in different electoral wards of one general practice with the Jarman and Townsend deprivation scores and unemployment rates. DESIGN--Analysis of computerised workload data. SETTING--General practice in centre of Mansfield, Nottinghamshire. OUTCOME MEASURE--Visits made in 588 nights to the 11,998 patients on the practice list. RESULTS--Night visit rates in 15 electoral wards varied from 19.6 to 55.3 visits per 1000 patients per year. The rates showed a significant association with the Townsend score (p = 0.004) and the unemployment rate (p = 0.03) but not with the Jarman score (p = 0.3). The Townsend score explained 49% of the variability; unemployment explained 31% and the Jarman score explained 9%. CONCLUSIONS--Even in a general practice not eligible for deprivation payments there was a 2.8-fold variation in night visit rates between wards. In this practice the Townsend score was significantly better at predicting night visit rates than the Jarman score. This method of looking at internal variation in workloads in computerised practices could give more direct data on the relation between deprivation and general practice workload than has previously been available. PMID:8518606

  7. Quality of HbA1c Measurement in the Practice: The German Perspective.

    PubMed

    Heinemann, Lutz; Freckmann, Guido

    2015-05-01

    Hemoglobin A1c (HbA1c) measurement has come to be a cornerstone in modern diabetes therapy. However, the methodological aspects of this type of measurement have been given little attention lately due to its position as an established method of choice. Nevertheless, quite a number of issues face practical application, such as clinically relevant differences between different measurement methods--both lab-based and point-of-care (POCT) systems will show better or worse diabetes management results after switching methods; and there are a number of possible reasons that need to be known and observed in practice. The aim of this review is to draw attention to these problems from a German point of view and provide suggestions for appropriate measures to improve the situation. PMID:25691655

  8. Quality of HbA1c Measurement in the Practice

    PubMed Central

    Freckmann, Guido

    2015-01-01

    Hemoglobin A1c (HbA1c) measurement has come to be a cornerstone in modern diabetes therapy. However, the methodological aspects of this type of measurement have been given little attention lately due to its position as an established method of choice. Nevertheless, quite a number of issues face practical application, such as clinically relevant differences between different measurement methods—both lab-based and point-of-care (POCT) systems will show better or worse diabetes management results after switching methods; and there are a number of possible reasons that need to be known and observed in practice. The aim of this review is to draw attention to these problems from a German point of view and provide suggestions for appropriate measures to improve the situation. PMID:25691655

  9. Community Health Centers and Private Practice Performance on Ambulatory Care Measures

    PubMed Central

    Goldman, L. Elizabeth; Chu, Philip W.; Tran, Huong; Stafford, Randall S.

    2013-01-01

    Background The 2010 Affordable Care Act relies on Federally Qualified Health Centers (FQHC) and FQHC look-alikes (look-alikes) to provide care for newly insured patients, but ties increased funding to demonstrated quality and efficiency. Purpose To compare FQHC and look-alike physician performance with private practice primary care physicians (PCPs) on ambulatory care quality measures. Methods The study was a cross-sectional analysis of visits in the 2006–2008 National Ambulatory Medical Care Survey. Performance of FQHCs and Look-alikes on 18 quality measures was compared with private practice PCPs. Data analysis was completed in 2011. Results Compared to private practice PCPs, FQHCs and look-alikes performed better on 6 measures (p<0.05), worse on diet counseling in at-risk adolescents (26 % vs. 36%, p=0.05), and no differently on 11 measures. Higher performance occurred in: ACE inhibitors use for congestive heart failure (51% vs. 37%, p=0.004); aspirin use in coronary artery disease (CAD) (57% vs. 44%, p=0.004); beta blocker use for CAD (59% vs. 47%, p=0.01); no use of benzodiazepines in depression (91% vs. 84%, p=0.008); blood pressure screening (90% vs. 86%, p<0.001); and screening electrocardiogram (EKG) avoidance in low-risk patients (99% vs. 93%, p<0.001). Adjusting for patient characteristics yielded similar results except private practice PCPs no longer performed better on any measures. Conclusions FQHCs and look-alikes demonstrated equal or better performance than private practice primary care physicians on select quality measures despite serving patients with more chronic disease and socioeconomic complexity. These findings can provide policymakers with some reassurance as to the quality of chronic disease and preventive care at Federally Qualified Health Centers and Federally Qualified Health Center look-alikes, as they plan to use these health centers to serve 20 million newly insured individuals. PMID:22813678

  10. New measures for new roles: defining and measuring the current practices of health sciences librarians

    PubMed Central

    Scherrer, Carol S.; Jacobson, Susan

    2002-01-01

    The roles of academic health sciences librarians are continually evolving as librarians initiate new programs and services in response to developments in computer technology and user demands. However, statistics currently collected by libraries do not accurately reflect or measure these new roles. It is essential for librarians to document, measure, and evaluate these new activities to continue to meet the needs of users and to ensure the viability of their professional role. To determine what new measures should be compiled, the authors examined current statistics, user demands, professional literature, and current activities of librarians as reported in abstracts of poster sessions at Medical Library Association annual meetings. Three new categories of services to be measured are proposed. The first, consultation, groups activities such as quality filtering and individual point-of-need instruction. The second, outreach, includes activities such as working as liaisons, participating in grand rounds or morning report, and providing continuing education. The third area, Web authoring, encompasses activities such as designing Web pages, creating online tutorials, and developing new products. Adding these three measures to those already being collected will provide a more accurate and complete depiction of the services offered by academic health sciences librarians. PMID:11999174

  11. New measures for new roles: defining and measuring the current practices of health sciences librarians.

    PubMed

    Scherrer, Carol S; Jacobson, Susan

    2002-04-01

    The roles of academic health sciences librarians are continually evolving as librarians initiate new programs and services in response to developments in computer technology and user demands. However, statistics currently collected by libraries do not accurately reflect or measure these new roles. It is essential for librarians to document, measure, and evaluate these new activities to continue to meet the needs of users and to ensure the viability of their professional role. To determine what new measures should be compiled, the authors examined current statistics, user demands, professional literature, and current activities of librarians as reported in abstracts of poster sessions at Medical Library Association annual meetings. Three new categories of services to be measured are proposed. The first, consultation, groups activities such as quality filtering and individual point-of-need instruction. The second, outreach, includes activities such as working as liaisons, participating in grand rounds or morning report, and providing continuing education. The third area, Web authoring, encompasses activities such as designing Web pages, creating online tutorials, and developing new products. Adding these three measures to those already being collected will provide a more accurate and complete depiction of the services offered by academic health sciences librarians. PMID:11999174

  12. Longitudinal 3-week tracking of blood glucose concentration from thermo-optical response measurements on human skin

    NASA Astrophysics Data System (ADS)

    Yeh, Shu-jen; Kantor, Stan; Hanna, Charles; Shain, Eric; Hohs, Ronald; Khalil, Omar S.

    2006-08-01

    We designed a dual-sensor instrument for measuring optical signals from the arms of human volunteers. The instrument had two temperature-controlled localized reflectance optical probes. Each probe had one illumination fiber and four detection fibers at different source-detector distances. The two probes were maintained at 30 °C. Thirty seconds after contact with the skin one was heated and the other was cooled at the same rate. The effect of heating and cooling on the signal was measured and correlated with blood glucose concentration. The measurements were performed 3 to 5 times a day for each volunteer over the span of three weeks. The data points from the first two weeks were used to establish a calibration model for each volunteer, which was used to predict glucose values from the third week optical data. Successftil calibration was possible for two of the three volunteers.

  13. Measuring Job Content: Skills, Technology, and Management Practices. Discussion Paper No. 1357-08

    ERIC Educational Resources Information Center

    Handel, Michael J.

    2008-01-01

    The conceptualization and measurement of key job characteristics has not changed greatly for most social scientists since the Dictionary of Occupational Titles and Quality of Employment surveys were created, despite their recognized limitations. However, debates over the roles of job skill requirements, technology, and new management practices in…

  14. Using the Leadership Practices Inventory to Measure Transformational and Transactional Leadership.

    ERIC Educational Resources Information Center

    Fields, Dail L.; Herold, David M.

    1997-01-01

    Investigated whether dimensions of transformational and transactional leadership can be inferred from subordinate reports of leadership behaviors collected through the Leadership Practices Inventory (LPI) (B. Posner and J. Kouzes, 1988) completed by 1,892 subordinates about 344 managers. Results support use of the LPI to measure transformation and…

  15. Measuring Classroom Assessment Practice Using Instructional Artifacts: A Validation Study of the QAS Notebook

    ERIC Educational Resources Information Center

    Martinez, Jose Felipe; Borko, Hilda; Stecher, Brian; Luskin, Rebecca; Kloser, Matt

    2012-01-01

    We report the results of a pilot validation study of the Quality Assessment in Science Notebook, a portfolio-like instrument for measuring teacher assessment practices in middle school science classrooms. A statewide sample of 42 teachers collected 2 notebooks during the school year, corresponding to science topics taught in the fall and spring.…

  16. Measuring Social Return on Investment for Community Schools: A Practical Guide

    ERIC Educational Resources Information Center

    Martinez, Laura; Hayes, Cheryl D.; Silloway, Torey

    2013-01-01

    Social return on investment (SROI) analysis offers a practical new approach for measuring and communicating the value of outcomes achieved by programs that provide social, health, and educational services to children and their families. This guide highlights the key steps in conducting SROI research, issues in data-gathering and analysis, as well…

  17. Measuring Parenting Practices among Parents of Elementary School-Age Youth

    ERIC Educational Resources Information Center

    Randolph, Karen A.; Radey, Melissa

    2011-01-01

    Objectives: The objective of this study is to establish the factor structure of the Alabama Parenting Questionnaire (APQ), an instrument designed to measure parenting practices among parents of elementary school children. Methods: Exploratory (EFA) and confirmatory factor analytic (CFA) procedures are used to validate the APQ with 790 parents of…

  18. Developing Common Measures in Evaluation Capacity Building: An Iterative Science and Practice Process

    ERIC Educational Resources Information Center

    Labin, Susan N.

    2014-01-01

    A fundamental reason for doing evaluation capacity building (ECB) is to improve program outcomes. Developing common measures of outcomes and the activities, processes, and factors that lead to these outcomes is an important step in moving the science and the practice of ECB forward. This article identifies a number of existing ECB measurement…

  19. A Dataset for Education-Related Majors' Performance Measures with Pre/Post-Video Game Practice

    ERIC Educational Resources Information Center

    Novak, Elena; Tassell, Janet Lynne

    2015-01-01

    This dataset includes a series of 30 education-related majors' performance measures before and after they completed a 10-hour video game practice in a computer lab. The goal of the experimental study was to examine the effects of action video gaming on students' mathematics performance and mathematics anxiety as mediated by the effect of attention…

  20. Evaluating and Improving a Learning Trajectory for Linear Measurement in Elementary Grades 2 and 3: A Longitudinal Study

    ERIC Educational Resources Information Center

    Barrett, Jeffrey E.; Sarama, Julie; Clements, Douglas H.; Cullen, Craig; McCool, Jenni; Witkowski-Rumsey, Chepina; Klanderman, David

    2012-01-01

    We examined children's development of strategic and conceptual knowledge for linear measurement. We conducted teaching experiments with eight students in grades 2 and 3, based on our hypothetical learning trajectory for length to check its coherence and to strengthen the domain-specific model for learning and teaching. We checked the hierarchical…

  1. Longitudinal Measurement Invariance of Likert-Type Learning Strategy Scales: Are We Using the Same Ruler at Each Wave?

    ERIC Educational Resources Information Center

    Coertjens, Liesje; Donche, Vincent; De Maeyer, Sven; Vanthournout, Gert; Van Petegem, Peter

    2012-01-01

    Whether or not learning strategies change during the course of higher education is an important topic in the Student Approaches to Learning field. However, there is a dearth of any empirical evaluations in the literature as to whether or not the instruments in this research domain measure equivalently over time. Therefore, this study details the…

  2. Correspondence between Physiological and Self-Report Measures of Emotion Dysregulation: A Longitudinal Investigation of Youth with and without Psychopathology

    ERIC Educational Resources Information Center

    Vasilev, Christina A.; Crowell, Sheila E.; Beauchaine, Theodore P.; Mead, Hilary K.; Gatzke-Kopp, Lisa M.

    2009-01-01

    Background: Several theoretical perspectives suggest that emotion dysregulation is a predisposing risk factor for many psychiatric disorders. Yet despite a rapidly evolving literature, difficulties with emotion regulation (ER) are often measured inconsistently across studies, with little regard to whether different approaches capture the same…

  3. Measuring primary care practice performance within an integrated delivery system: a case study.

    PubMed

    Stewart, Louis J; Greisler, David

    2002-01-01

    This article examines the use of an integrated performance measurement system to plan and control primary care service delivery within an integrated delivery system. We review a growing body of literature that focuses on the development and implementation of management reporting systems among healthcare providers. Our study extends the existing literature by examining the use of performance information generated by an integrated performance measurement system within a healthcare organization. We conduct our examination through a case study of the WMG Primary Care Medicine Group, the primary care medical group practice of WellSpan Health System. WellSpan Health System is an integrated delivery system that serves south central Pennsylvania and northern Maryland. Our study examines the linkage between WellSpan Health's strategic objectives and its primary care medicine group's integrated performance measurement system. The conceptual design of this integrated performance measurement system combines financial metrics with practice management and clinical operating metrics to provide a more complete picture of medical group performance. Our findings demonstrate that WellSpan Health was able to achieve superior financial results despite a weak linkage between its integrated performance measurement system and its strategic objectives. WellSpan Health achieved this objective for its primary care medicine group by linking clinical performance information to physician compensation and reporting practice management performance through the use of statistical process charts. They found that the combined mechanisms of integrated performance measurement and statistical process control charts improved organizational learning and communications between organizational stakeholders. PMID:12221746

  4. The Role of Measurement Quality on Practical Guidelines for Assessing Measurement and Structural Invariance

    ERIC Educational Resources Information Center

    Kang, Yoonjeong; McNeish, Daniel M.; Hancock, Gregory R.

    2016-01-01

    Although differences in goodness-of-fit indices (?GOFs) have been advocated for assessing measurement invariance, studies that advanced recommended differential cutoffs for adjudicating invariance actually utilized a very limited range of values representing the quality of indicator variables (i.e., magnitude of loadings). Because quality of…

  5. Using Longitudinal Data to Increase Community College Student Success: A Guide to Measuring Milestone and Momentum Point Attainment. CCRC Research Tools No. 2

    ERIC Educational Resources Information Center

    Leinbach, D. Timothy; Jenkins, Davis

    2008-01-01

    Longitudinal student unit record (SUR) data can be used to answer many important questions about student progression. This guide shows researchers how to use longitudinal SUR data to identify different student groups among first-time community college students, calculate rates of attainment of milestones and momentum points for each group, and…

  6. The Practical Implementation of Non-Contacting Laser Strain Measurements Systems

    NASA Technical Reports Server (NTRS)

    Yunis, Isam; Quinn, roger D.; Kadambi, Jaikrishnan R.

    2000-01-01

    Measurement of stress and strain in rotating turbomachinery is critical to many industries. The search for a non-contacting, non-interfering, non-degrading measurement system is on going and extensive. While several methods seem promising in theory, implementation has proven troublesome. This work uncovers and quantifies these implementation issues in the context of a laser measurement system. Both a Laser Doppler Velocimeter system and a displacement laser system are utilized. It is found that the key issues are signal to noise ratio, rigid body compensation, measurement location, and conversion of intermittent measurements to a continuous signal. Accounting for these factors leads to successful measurements. These results should lead to better ideas and more practical solutions to the non-contacting, non-degrading, non-interfering strain measurement system problem.

  7. Measuring changes in water-related health and hygiene practices by developing-community households.

    PubMed

    Jagals, P; Nala, N P; Tsubane, T J; Moabi, M; Motaung, K C

    2004-01-01

    A population sample from a community in a developing urban area (Botshabelo), which obtains its treated water supply from a communal standpipe system, was subjected to a short Health and Hygiene Awareness and Education (HHA&E) programme to improve its practices on storing water in, and handling water from, storage containers at home. The problem was that the community's practices lead to the deterioration of the microbiological quality of the water in domestic storage containers. Measuring changes in the practices, as well as the microbiological quality of water in the containers, were the instruments used to determine whether the programme had a positive educational effect. This paper reports on selected elements of the practices measurement. Structured interviews, observations and statistical analyses assessed three variables--container hygiene, container storage and hand hygiene. Results indicated insignificant improvements in practices. This was supported by insignificant improvements in the microbiological water quality, that was still above health-safety limits. This implied that short-term "quick fix" HHA&E programmes would tend to be ineffective. Results also suggested that some negative water-hygiene habits may readily change (container hygiene and storage), while behaviour of a more personal nature, such as hand-washing, was not easily changed. PMID:15318492

  8. The Impact of Electronic Health Records on Workflow and Financial Measures in Primary Care Practices

    PubMed Central

    Fleming, Neil S; Becker, Edmund R; Culler, Steven D; Cheng, Dunlei; McCorkle, Russell; da Graca, Briget; Ballard, David J

    2014-01-01

    Objective To estimate a commercially available ambulatory electronic health record’s (EHR’s) impact on workflow and financial measures. Data Sources/Study Setting Administrative, payroll, and billing data were collected for 26 primary care practices in a fee-for-service network that rolled out an EHR on a staggered schedule from June 2006 through December 2008. Study Design An interrupted time series design was used. Staffing, visit intensity, productivity, volume, practice expense, payments received, and net income data were collected monthly for 2004–2009. Changes were evaluated 1–6, 7–12, and >12 months postimplementation. Data Collection/Extraction Methods Data were accessed through a SQLserver database, transformed into SAS®, and aggregated by practice. Practice-level data were divided by full-time physician equivalents for comparisons across practices by month. Principal Findings Staffing and practice expenses increased following EHR implementation (3 and 6 percent after 12 months). Productivity, volume, and net income decreased initially but recovered to/close to preimplementation levels after 12 months. Visit intensity did not change significantly, and a secular trend offset the decrease in payments received. Conclusions Expenses increased and productivity decreased following EHR implementation, but not as much or as persistently as might be expected. Longer term effects still need to be examined. PMID:24359533

  9. Spectropolarimetric measurements of the mean longitudinal magnetic field of chemically peculiar stars. II. Phase relating the magnetic and luminosity variabilities

    NASA Astrophysics Data System (ADS)

    Leone, F.; Catanzaro, G.

    2001-01-01

    For a sample of chemically peculiar stars, we report time-resolved measurements of the effective magnetic field which were obtained with the spectropolarimetry operating at the Catania Astrophysical Observatory. These observations are combined with data from the literature for better pointing out that periodic magnetic variability which characterises this class of stars. Periods given in the literature have been checked and, if possible, re-determined, not only by means of the magnetic measurements but referring also to the Hipparcos photometry. The variability of the effective magnetic field of the already known magnetic star 25 Sex is pointed out for the first time. As to the suspected magnetic chemically peculiar star EP UMa, our measurements confirm that this is really a magnetic star and we indicate a possible variability period. The accuracy of the variability period for CS Vir and FF Vir is improved. The suggestion that light variability is due to the re-distribution of ultraviolet flux towards the visible wavelengths in metal rich regions, which are not homogeneously distributed on the stellar surface, appears not always and straightly valid. Local line-blocking is certainly important in the case of CS Vir and a direct influence of the magnetic field on the infrared photometric variability cannot be ruled out for 25 Sex. Based on observations collected at the Catania Astrophysical Observatory, Italy.

  10. In-plane ultrasonic velocity measurement of longitudinal and shear waves in the machine direction with transducers in rotating wheels

    DOEpatents

    Hall, M.S.; Jackson, T.G.; Knerr, C.

    1998-02-17

    An improved system for measuring the velocity of ultrasonic signals within the plane of moving web-like materials, such as paper, paperboard and the like. In addition to velocity measurements of ultrasonic signals in the plane of the web in the MD and CD, one embodiment of the system in accordance with the present invention is also adapted to provide on-line indication of the polar specific stiffness of the moving web. In another embodiment of the invention, the velocity of ultrasonic signals in the plane of the web are measured by way of a plurality of ultrasonic transducers carried by synchronously driven wheels or cylinders, thus eliminating undue transducer wear due to any speed differences between the transducers and the web. In order to provide relatively constant contact force between the transducers and the webs, the transducers are mounted in a sensor housings which include a spring for biasing the transducer radially outwardly. The sensor housings are adapted to be easily and conveniently mounted to the carrier to provide a relatively constant contact force between the transducers and the moving web. 37 figs.

  11. In-plane ultrasonic velocity measurement of longitudinal and shear waves in the machine direction with transducers in rotating wheels

    DOEpatents

    Hall, Maclin S.; Jackson, Theodore G.; Knerr, Christopher

    1998-02-17

    An improved system for measuring the velocity of ultrasonic signals within the plane of moving web-like materials, such as paper, paperboard and the like. In addition to velocity measurements of ultrasonic signals in the plane of the web in the MD and CD, one embodiment of the system in accordance with the present invention is also adapted to provide on-line indication of the polar specific stiffness of the moving web. In another embodiment of the invention, the velocity of ultrasonic signals in the plane of the web are measured by way of a plurality of ultrasonic transducers carried by synchronously driven wheels or cylinders, thus eliminating undue transducer wear due to any speed differences between the transducers and the web. In order to provide relatively constant contact force between the transducers and the webs, the transducers are mounted in a sensor housings which include a spring for biasing the transducer radially outwardly. The sensor housings are adapted to be easily and conveniently mounted to the carrier to provide a relatively constant contact force between the transducers and the moving web.

  12. Correlation of shoulder and elbow injuries with muscle tightness, core stability, and balance by longitudinal measurements in junior high school baseball players.

    PubMed

    Endo, Yasuhiro; Sakamoto, Masaaki

    2014-05-01

    [Purpose] The present study longitudinally investigated injury occurrences and the risk factors for muscle tightness, core stability, and dynamic standing balance among junior high school student baseball players. [Subjects] Thirty-nine male students, belonging to baseball clubs at 2 junior high schools, participated in this study. [Methods] Study measurements were obtained twice, once in the early stage of the baseball season (March) and once at the end of the season (July). All subjects underwent muscle tightness testing, the Star Excursion Balance Test (SEBT), and trunk endurance testing during each measurement session. [Results] Fifteen players experienced episodes of elbow or shoulder pain while throwing. Players in the pain group demonstrated a significant increase in the tightness of their shoulder internal rotators, axis-leg quadriceps, and axis-leg hamstrings. There was no clear evidence of differences of changes in core stability and dynamic standing balance between the groups. [Conclusion] The results of this study suggest that lower extremity muscle tightness early in a season and the subsequent decline in the flexibility of the axis-leg quadriceps and hamstrings during the season may be due to an increased upper extremity load while throwing, thus producing shoulder and elbow pain. PMID:24926133

  13. First measurements of the longitudinal bunch profile of a 28.5GeV beam using coherent Smith-Purcell radiation

    NASA Astrophysics Data System (ADS)

    Blackmore, V.; Doucas, G.; Perry, C.; Ottewell, B.; Kimmitt, M. F.; Woods, M.; Molloy, S.; Arnold, R.

    2009-03-01

    Coherent Smith-Purcell (SP) radiation originating from three different gratings has been measured at End Station A, SLAC, and has been used to reconstruct the time profile of the electron bunches. The beam energy during these experiments was 28.5 GeV (γ≅55773) and the number of electrons in the bunch was 0.9-1.4×1010. The spectral distribution of the radiated energy was measured by means of an array of 11 pyroelectric detectors. Typical values of the FWHM of the bunch length are about 2.5 ps, but sharper peaks with FWHM less than 2.0 ps have also been observed. The longitudinal profile also varies with accelerator conditions and can best be approximated by a superposition of 3-4 Gaussian curves. Some typical profiles are presented, together with a discussion of the limitations and strengths of coherent SP radiation as a diagnostic tool. It is concluded that SP radiation offers excellent prospects in this respect, not only in the picosecond range, but potentially in the femtosecond range as well.

  14. Longitudinal measures of cognition in the Ts65Dn mouse: Refining windows and defining modalities for therapeutic intervention in Down syndrome.

    PubMed

    Olmos-Serrano, J Luis; Tyler, William A; Cabral, Howard J; Haydar, Tarik F

    2016-05-01

    Mouse models have provided insights into adult changes in learning and memory in Down syndrome, but an in-depth assessment of how these abnormalities develop over time has never been conducted. To address this shortcoming, we conducted a longitudinal behavioral study from birth until late adulthood in the Ts65Dn mouse model to measure the emergence and continuity of learning and memory deficits in individuals with a broad array of tests. Our results demonstrate for the first time that the pace at which neonatal and perinatal milestones are acquired is correlated with later cognitive performance as an adult. In addition, we find that life-long behavioral indexing stratifies mice within each genotype. Our expanded assessment reveals that diminished cognitive flexibility, as measured by reversal learning, is the most robust learning and memory impairment in both young and old Ts65Dn mice. Moreover, we find that reversal learning degrades with age and is therefore a useful biomarker for studying age-related decline in cognitive ability. Altogether, our results indicate that preclinical studies aiming to restore cognitive function in Ts65Dn should target both neonatal milestones and reversal learning in adulthood. Here we provide the quantitative framework for this type of approach. PMID:26854932

  15. Distinguishing State Variability From Trait Change in Longitudinal Data: The Role of Measurement (Non)Invariance in Latent State-Trait Analyses

    PubMed Central

    Geiser, Christian; Keller, Brian T.; Lockhart, Ginger; Eid, Michael; Cole, David A.; Koch, Tobias

    2014-01-01

    Researchers analyzing longitudinal data often want to find out whether the process they study is characterized by (1) short-term state variability, (2) long-term trait change, or (3) a combination of state variability and trait change. Classical latent state-trait (LST) models are designed to measure reversible state variability around a fixed set-point or trait, whereas latent growth curve (LGC) models focus on long-lasting and often irreversible trait changes. In the present paper, we contrast LST and LGC models from the perspective of measurement invariance (MI) testing. We show that establishing a pure state-variability process requires (a) the inclusion of a mean structure and (b) establishing strong factorial invariance in LST analyses. Analytical derivations and simulations demonstrate that LST models with non-invariant parameters can mask the fact that a trait-change or hybrid process has generated the data. Furthermore, the inappropriate application of LST models to trait change or hybrid data can lead to bias in the estimates of consistency and occasion-specificity, which are typically of key interest in LST analyses. Four tips for the proper application of LST models are provided. PMID:24652650

  16. Indicators of Club Management Practices and Biological Measurements of Patrons’ Drug and Alcohol Use

    PubMed Central

    Byrnes, Hilary F.; Miller, Brenda A.; Johnson, Mark B.; Voas, Robert B.

    2015-01-01

    Background Electronic Music Dance Events in nightclubs attract patrons with heavy alcohol/drug use. Public health concerns are raised from risks related to these behaviors. Practices associated with increased risk in these club settings need to be identified. Objectives The relationship between club management practices and biological measures of patrons’ alcohol/drug use is examined. Methods Observational data from 25 events across 6 urban clubs were integrated with survey data (N=738 patrons, 42.8% female) from patrons exiting these events, 2010–2012. Five indicators of club management practices were examined using mixed model regressions: club security, bar crowding, safety signs, serving intoxicated patrons, and isolation. Results Analyses revealed that serving intoxicated patrons and safety signs were related to less substance use. Specifically, serving intoxicated patrons was related to heavy alcohol and drug use at exit, while safety signs were marginally related to less exit drug use. Conclusions/Importance Findings indicate observable measures in nightclubs provide important indicators for alcohol/drug use, suggesting practices to target. Study strengths include the use of biological measures of substance use on a relatively large scale. Limitations and future directions are discussed. PMID:24832721

  17. Errors in longitudinal measurements of bone mineral: effect of source strength in single and dual photon absorptiometry

    SciTech Connect

    Dunn, W.L.; Kan, S.H.; Wahner, H.W.

    1987-11-01

    The effect of changing strength during the useful life of a radiation source was evaluated in studies performed on four dual photon (DPA) and two single photon (SPA) bone absorptiometry instruments. Two DPA units and one SPA unit did not show any systematic dependence of measured bone mineral content or bone mineral areal density (BMD) on source activity when evaluated over an entire source life. One DPA and one SPA instrument, however, showed significant time trends associated with source activity. The fourth DPA instrument had a significant linear decrease in BMD over a source life in the automatic mode but performed better in the manual mode.

  18. The Longitudinal Guttman Simplex: Applications to Health Behavior Data.

    ERIC Educational Resources Information Center

    Collins, Linda M.; Dent, Clyde W.

    Because health behavior is often concerned with dynamic constructs, a longitudinal approach to measurement is needed. The Longitudinal Guttman Simplex (LGS) is a measurement model developed especially for dynamic constructs exhibiting cumulative, unitary development measured longitudinally. Data from the Television Smoking Prevention Project, a…

  19. Longitudinal measurement of cortisol in association with mental health and experience of domestic violence and abuse: study protocol

    PubMed Central

    2013-01-01

    Background Domestic violence and abuse is threatening behavior, violence/abuse used by one person to control the other within an intimate or family-type relationship. Women experience more severe physical and sexual domestic violence and abuse and more mental health consequences than men. The current study aims at exploring of the role of hypothalamic-pituitary-adrenocortical axis activity in abuse impact on women's mental health. Study objectives: 1) To evaluate diurnal cortisol slope, cortisol awakening response, and the mean cortisol concentration in women with a current or recent experience of abuse; 2) To estimate whether cortisol secretion is associated with type, severity, duration and cessation of abuse; 3) To investigate whether cortisol acts as mediator between abuse and mental health condition; 4) To examine whether there is any distinction in cortisol levels between those women exposed to both childhood abuse and domestic violence and abuse and those experienced only the latter. 4) To explore whether cortisol secretion differs between women living in refuge and those still living in the community. Methods/Design To meet study objectives 128 women will be recruited in a domestic violence agency and local communities. Baseline and 3-month follow-up measures will be taken over 6 months after recruitment. Each assessment will include: (1) standardized self-administered questionnaires to evaluate socio-demographics, experience of violence and abuse, mental and physical health; (2) weight and height measurement; (3) self-completion of wakening, post-wakening and evening saliva samples. Saliva will be analysed for cortisol and cortisone using Ultra performance liquid chromatography – tandem mass spectrometry. We will compare diurnal cortisol parameters between non-abused controls and abuse survivors with and without mental health conditions. First following descriptive statistics for all the cortisol and mental health outcomes, relationships between them

  20. Change and Stability in Active and Passive Social Influence Dynamics during Natural Drinking Events: A Longitudinal Measurement-Burst Study

    PubMed Central

    Cullum, Jerry; O’Grady, Megan; Armeli, Stephen; Tennen, Howard

    2011-01-01

    We examined the link between social norms and active social influences occurring during natural social drinking contexts. Across 4 yearly measurement-bursts, college students (N = 523) reported daily for 30-day periods on drinking norms, drinking offers, how many drinks they accepted, and personal drinking levels during social drinking events. In contexts where drinking norms were higher, students were more likely to both receive and comply with drinking offers. These acute social influences were highly stable throughout college, but affected men and women differently across time: Women received more drinking offers than men, especially at the beginning of college and when norms were higher, but men complied with more drinking offers per occasion. These effects were not attributable to between-person differences in social drinking motives or drinking levels, nor to within-person patterns of situation-selection. The present work suggests that context-specific drinking norms catalyze active social influence attempts, and further promote compliance drinking. PMID:22661826

  1. Evaluation of the influence of cardiac motion on the accuracy and reproducibility of longitudinal measurements and the corresponding image quality in optical frequency domain imaging: an ex vivo investigation of the optimal pullback speed.

    PubMed

    Koyama, Kohei; Yoneyama, Kihei; Mitarai, Takanobu; Kuwata, Shingo; Kongoji, Ken; Harada, Tomoo; Akashi, Yoshihiro J

    2015-08-01

    Longitudinal measurement using intravascular ultrasound is limited because the motorized pullback device assumes no cardiac motion. A newly developed intracoronary imaging modality, optical frequency domain imaging (OFDI), has higher resolution and an increased auto-pullback speed with presumably lesser susceptibility to cardiac motion artifacts during pullback for longitudinal measurement; however, it has not been fully investigated. We aimed to clarify the influence of cardiac motion on the accuracy and reproducibility of longitudinal measurements obtained using OFDI and to determine the optimal pullback speed. This ex vivo study included 31 stents deployed in the mid left anterior descending artery under phantom heartbeat and coronary flow simulation. Longitudinal stent lengths were measured twice using OFDI at three pullback speeds. Differences in stent lengths between OFDI and microscopy and between two repetitive pullbacks were assessed to determine accuracy and reproducibility. Furthermore, three-dimensional (3D) reconstruction was used for evaluating image quality. With regard to differences in stent length between OFDI and microscopy, the intraclass correlation coefficient values were 0.985, 0.994, and 0.995 at 10, 20, and 40 mm/s, respectively. With regard to reproducibility, the values were 0.995, 0.996, and 0.996 at 10, 20, and 40 mm/s, respectively. 3D reconstruction showed a superior image quality at 10 and 20 mm/s compared with that at 40 mm/s. OFDI demonstrated high accuracy and reproducibility for longitudinal stent measurements. Moreover, its accuracy and reproducibility were remarkable at a higher pullback speed. A 20-mm/s pullback speed may be optimal for clinical and research purposes. PMID:25971841

  2. Measuring Science Instructional Practice: A Survey Tool for the Age of NGSS

    NASA Astrophysics Data System (ADS)

    Hayes, Kathryn N.; Lee, Christine S.; DiStefano, Rachelle; O'Connor, Dawn; Seitz, Jeffery C.

    2016-03-01

    Ambitious efforts are taking place to implement a new vision for science education in the United States, in both Next Generation Science Standards (NGSS)-adopted states and those states creating their own, often related, standards. In-service and pre-service teacher educators are involved in supporting teacher shifts in practice toward the new standards. With these efforts, it will be important to document shifts in science instruction toward the goals of NGSS and broader science education reform. Survey instruments are often used to capture instructional practices; however, existing surveys primarily measure inquiry based on previous definitions and standards and with a few exceptions, disregard key instructional practices considered outside the scope of inquiry. A comprehensive survey and a clearly defined set of items do not exist. Moreover, items specific to the NGSS Science and Engineering practices have not yet been tested. To address this need, we developed and validated a Science Instructional Practices survey instrument that is appropriate for NGSS and other related science standards. Survey construction was based on a literature review establishing key areas of science instruction, followed by a systematic process for identifying and creating items. Instrument validity and reliability were then tested through a procedure that included cognitive interviews, expert review, exploratory and confirmatory factor analysis (using independent samples), and analysis of criterion validity. Based on these analyses, final subscales include: Instigating an Investigation, Data Collection and Analysis, Critique, Explanation and Argumentation, Modeling, Traditional Instruction, Prior Knowledge, Science Communication, and Discourse.

  3. Pragmatic Characteristics of Patient-Reported Outcome Measures are Important for Use in Clinical Practice

    PubMed Central

    Kroenke, Kurt; Monahan, Patrick O.; Kean, Jacob

    2015-01-01

    Objective Measures for assessing patient-reported outcomes (PROs) that may have initially been developed for research are increasingly being recommended for use in clinical practice as well. While psychometric rigor is essential, this paper focuses on pragmatic characteristics of PROs that may enhance uptake into clinical practice. Methods Three sources were drawn upon in identifying pragmatic criteria for PROs: 1) selected literature review including recommendations by other expert groups; 2) key features of several model public domain PROs; 3) the author' experience in developing practical PROs. Results Eight characteristics of a practical PRO include: 1) actionability (i.e., scores guide diagnostic or therapeutic actions/decision-making); 2) appropriateness for the relevant clinical setting; 3) universality (i.e., for screening, severity assessment, and monitoring across multiple conditions); 4) self-administration; 5) item features (number of items and bundling issues); 6) response options (option number and dimensions, uniform vs. varying options, timeframe, intervals between options); 7) scoring (simplicity, interpretability); and 8) accessibility (nonproprietary, downloadable, available in different languages and for vulnerable groups, incorporated into electronic health records) Conclusion Balancing psychometric and pragmatic factors in the development of PROs is important for accelerating the incorporation of PROs into clinical practice. PMID:25962972

  4. Measuring nursing informatics competencies of practicing nurses in Korea: Nursing Informatics Competencies Questionnaire.

    PubMed

    Chung, Seon Yoon; Staggers, Nancy

    2014-12-01

    Informatics competencies are a necessity for contemporary nurses. However, few researchers have investigated informatics competencies for practicing nurses. A full set of Informatics competencies, an instrument to measure these competencies, and potential influencing factors have yet to be identified for practicing nurses. The Nursing Informatics Competencies Questionnaire was designed, tested for psychometrics, and used to measure beginning and experienced levels of practice. A pilot study using 54 nurses ensured item comprehension and clarity. Internal consistency and face and content validity were established. A cross-sectional survey was then conducted on 230 nurses in Seoul, Korea, to determine construct validity, describe a complete set of informatics competencies, and explore possible influencing factors on existing informatics competencies. Principal components analysis, descriptive statistics, and multiple regression were used for data analysis. Principal components analysis gives support for the Nursing Informatics Competencies Questionnaire construct validity. Survey results indicate that involvement in a managerial position and self-directed informatics-related education may be more influential for improving informatics competencies, whereas general clinical experience and workplace settings are not. This study provides a foundation for understanding how informatics competencies might be integrated throughout nurses' work lives and how to develop appropriate strategies to support nurses in their informatics practice in clinical settings. PMID:25393832

  5. A 30-month longitudinal study of the effects of some oral hygiene measures on Streptococcus mutans and approximal dental caries.

    PubMed

    Axelsson, P; Kristoffersson, K; Karlsson, R; Bratthall, D

    1987-03-01

    The effects of some oral hygiene measures on Streptococcus mutants and approximal dental caries were evaluated. One hundred and eighty-seven 13-year-old individuals with high levels of salivary S. mutans (greater than 10(6)/mL) were selected. They were randomly distributed into three groups. Group I initially received professional mechanical tooth-cleaning, tongue-scraping, chlorhexidine treatment, and oral hygiene instructions concentrated on the approximal surfaces most colonized by S. mutans. The treatment was given four times with intervals of two days, followed by one single treatment every six months throughout the experimental period. The initial treatment period for group II, also consisting of four visits, included the same oral hygiene instructions as for group I. The instructions were repeated every six months. Group III was maintained in the preventive program provided by the local Dental Health Office, based on mechanical plaque control and topical use of fluorides and chlorhexidine at individualized intervals. Group I showed a significant immediate reduction of S. mutans in saliva as well as an approximal tooth surfaces. After six months, there were no differences among the three groups regarding these variables. Compared with baseline, there was a significant reduction of S. mutans in all groups. There was no significant difference in caries progression among the three groups. However, the selected "high-risk" individuals in group I developed 0.25 new manifest caries lesions approximally/year, compared with 0.27 for all children of the same age group in the area. Seventeen individuals had approximal surfaces with consistently high or consistently low S. mutans levels. Forty-six percent of the surfaces with high values developed new or progressive caries, compared with 2% of the surfaces with low values. PMID:3475309

  6. Research on Scaling up Evidence-Based Instructional Practice: Developing a Sensitive Measure of the Rate of Implementation

    ERIC Educational Resources Information Center

    Buzhardt, Jay; Greenwood, Charles R.; Abbott, Mary; Tapia, Yolanda

    2006-01-01

    Few evidence-based instructional practices achieve large-scale use, often remaining only in the schools directly involved in their development. Research on scaling up effective educational practice often lacks sensitive measures of the practice's implementation and the required research protocol. This article describes how we used rate of…

  7. Rapid, Accurate, and Non-Invasive Measurement of Zebrafish Axial Length and Other Eye Dimensions Using SD-OCT Allows Longitudinal Analysis of Myopia and Emmetropization

    PubMed Central

    Collery, Ross F.; Veth, Kerry N.; Dubis, Adam M.; Carroll, Joseph; Link, Brian A.

    2014-01-01

    Refractive errors in vision can be caused by aberrant axial length of the eye, irregular corneal shape, or lens abnormalities. Causes of eye length overgrowth include multiple genetic loci, and visual parameters. We evaluate zebrafish as a potential animal model for studies of the genetic, cellular, and signaling basis of emmetropization and myopia. Axial length and other eye dimensions of zebrafish were measured using spectral domain-optical coherence tomography (SD-OCT). We used ocular lens and body metrics to normalize and compare eye size and relative refractive error (difference between observed retinal radial length and controls) in wild-type and lrp2 zebrafish. Zebrafish were dark-reared to assess effects of visual deprivation on eye size. Two relative measurements, ocular axial length to body length and axial length to lens diameter, were found to accurately normalize comparisons of eye sizes between different sized fish (R2 = 0.9548, R2 = 0.9921). Ray-traced focal lengths of wild-type zebrafish lenses were equal to their retinal radii, while lrp2 eyes had longer retinal radii than focal lengths. Both genetic mutation (lrp2) and environmental manipulation (dark-rearing) caused elongated eye axes. lrp2 mutants had relative refractive errors of −0.327 compared to wild-types, and dark-reared wild-type fish had relative refractive errors of −0.132 compared to light-reared siblings. Therefore, zebrafish eye anatomy (axial length, lens radius, retinal radius) can be rapidly and accurately measured by SD-OCT, facilitating longitudinal studies of regulated eye growth and emmetropization. Specifically, genes homologous to human myopia candidates may be modified, inactivated or overexpressed in zebrafish, and myopia-sensitizing conditions used to probe gene-environment interactions. Our studies provide foundation for such investigations into genetic contributions that control eye size and impact refractive errors. PMID:25334040

  8. Accuracy of self-reported versus measured weight over adolescence and young adulthood: findings from the national longitudinal study of adolescent health, 1996-2008.

    PubMed

    Clarke, Philippa; Sastry, Narayan; Duffy, Denise; Ailshire, Jennifer

    2014-07-15

    Many studies rely on self-reports to capture population trends and trajectories in weight gain over adulthood, but the validity of self-reports is often considered a limitation. The purpose of this work was to examine long-term trajectories of self-reporting bias in a national sample of American youth. With 3 waves of data from the National Longitudinal Study of Adolescent Health (1996-2008), we used growth curve models to examine self-reporting bias in trajectories of weight gain across adolescence and early adulthood (ages 13-32 years). We investigated whether self-reporting bias is constant over time, or whether adolescents become more accurate in reporting their weight as they move into young adulthood, and we examined differences in self-reporting bias by sex, race/ethnicity, and attained education. Adolescent girls underreported their weight by 0.86 kg on average, and this rate of underreporting increased over early adulthood. In contrast, we found no evidence that boys underreported their weight either in adolescence or over the early adult years. For young men, self-reports of weight were unbiased estimates of measured weight among all racial/ethnic and educational subpopulations over adolescence and early adulthood. PMID:24944288

  9. Measurement of unmet need for family planning: Longitudinal analysis of the impact of fertility desires on subsequent childbearing behaviors among urban women from Uttar Pradesh India

    PubMed Central

    Speizer, Ilene S.; Calhoun, Lisa; Hoke, Theresa; Sengupta, Ranajit

    2013-01-01

    Background The measure of unmet need relies on women’s reported fertility desires; previous research has demonstrated that fertility desires may be fluid and not firm. Study design Our study uses recently collected longitudinal data from four cities in Uttar Pradesh India to examine whether women’s fertility desires and family planning (FP) use at baseline predict pregnancy/birth experience in the two-year follow-up period. Results Multivariate models demonstrate that women who were using any method of FP and reported an intention to stop childbearing were the least likely to experience a pregnancy/birth in the two-year follow-up period. The stated desire to delay childbearing, whether or not the woman was using FP did not distinguish pregnancy/birth experience. Ninety- two percent of pregnancies/births over the follow-up period were considered “wanted then” suggesting post hoc rationalization of the pregnancy/birth even among those women who reported a desire to stop childbearing two years earlier. Conclusions More nuanced assessments of fertility intentions may be needed to adequately gauge latent family planning needs. Non-users of FP may be ambivalent about future childbearing and the timing of future births; these women may not have an unmet need for FP as typically defined. PMID:23706906

  10. Measurements of the Longitudinal Stability and Control and Stalling Characteristics of a North American P-51H Airplane (AAF No. 4-64164)

    NASA Technical Reports Server (NTRS)

    Kraft, Christopher C., Jr.; Reeder, J. P.

    1948-01-01

    Flight tests have been made to determine the longitudinal stability and control and stalling characteristics of a North American P-51H airplane. The results indicate that the airplane has satisfactory longitudinal stability in all the flight conditions tested at normal loadings up to 25,000 feet altitude. At Mach numbers above 0.7, the elevator push force required for longitudinal trim decreased somewhat because of compressibility effects. The elevator stick force per g in accelerated turns at the forward center-of-gravity position of 24 percent mean aerodynamic chord above 250 miles per hour was in excess of the required limits at both 5,000 and 25,OOO feet altitude. The longitudinal-trim-force changes due to flaps and power were small, but the rudder-trim-force change with power change was high. The stalling characteristics in all the conditions tested were satisfactory.

  11. Citizenship Education Longitudinal Study: Second Cross-Sectional Survey, 2004. Listening to Young People: Citizenship Education in England. Research Report RR626

    ERIC Educational Resources Information Center

    Cleaver, Elizabeth; Ireland, Eleanor; Kerr, David; Lopes, Joana

    2006-01-01

    The Citizenship Education Longitudinal Study, conducted by the National Foundation for Education Research (NFER) on behalf of the Department for Education and Skills (DfES), aims to identify, measure and evaluate the extent to which effective practice in citizenship education develops in schools so that such practice can be promoted widely. The…

  12. How to Measure Motivational Interviewing Fidelity in Randomized Controlled Trials: Practical Recommendations.

    PubMed

    Jelsma, Judith G M; Mertens, Vera-Christina; Forsberg, Lisa; Forsberg, Lars

    2015-07-01

    Many randomized controlled trials in which motivational interviewing (MI) is a key intervention make no provision for the assessment of treatment fidelity. This methodological shortcoming makes it impossible to distinguish between high- and low-quality MI interventions, and, consequently, to know whether MI provision has contributed to any intervention effects. This article makes some practical recommendations for the collection, selection, coding and reporting of MI fidelity data, as measured using the Motivational Interviewing Treatment Integrity Code. We hope that researchers will consider these recommendations and include MI fidelity measures in future studies. PMID:25962891

  13. Assessing methods for measurement of clinical outcomes and quality of care in primary care practices

    PubMed Central

    2012-01-01

    Purpose To evaluate the appropriateness of potential data sources for the population of performance indicators for primary care (PC) practices. Methods This project was a cross sectional study of 7 multidisciplinary primary care teams in Ontario, Canada. Practices were recruited and 5-7 physicians per practice agreed to participate in the study. Patients of participating physicians (20-30) were recruited sequentially as they presented to attend a visit. Data collection included patient, provider and practice surveys, chart abstraction and linkage to administrative data sets. Matched pairs analysis was used to examine the differences in the observed results for each indicator obtained using multiple data sources. Results Seven teams, 41 physicians, 94 associated staff and 998 patients were recruited. The survey response rate was 81% for patients, 93% for physicians and 83% for associated staff. Chart audits were successfully completed on all but 1 patient and linkage to administrative data was successful for all subjects. There were significant differences noted between the data collection methods for many measures. No single method of data collection was best for all outcomes. For most measures of technical quality of care chart audit was the most accurate method of data collection. Patient surveys were more accurate for immunizations, chronic disease advice/information dispensed, some general health promotion items and possibly for medication use. Administrative data appears useful for indicators including chronic disease diagnosis and osteoporosis/ breast screening. Conclusions Multiple data collection methods are required for a comprehensive assessment of performance in primary care practices. The choice of which methods are best for any one particular study or quality improvement initiative requires careful consideration of the biases that each method might introduce into the results. In this study, both patients and providers were willing to participate in and

  14. Exploring nurses' perceptions of collecting and using HOBIC measures to guide clinical practice and improve care.

    PubMed

    Jeffs, Lianne; Wilson, Gail; Ferris, Ella; Cardiff, Brenda; Ng, San; Lanceta, Mary; White, Peggy; Pringle, Dorothy

    2012-03-01

    Ontario's Health Outcomes for Better Information and Care (HOBIC) is designed to help organizations and nurses plan and evaluate care by comparing patient outcomes with historical data on similar cases. Yet, fewer than 15% of patients in a 2010 study were found to have complete admission and discharge data sets. This low utilization rate of HOBIC measures prompted the current qualitative study, in which nurses from three clinical settings in an academic teaching hospital were interviewed to gain their perceptions related to collecting and using HOBIC measures in practice. The objective was to identify factors that promote or impede the collection and use of HOBIC data in clinical practice to improve patient care and outcomes. Analysis of interview results produced four key themes related to (a) use of HOBIC measures to inform patient care, (b) collecting and documenting HOBIC measures, (c) HOBIC as an afterthought and "black hole" and (d) impediments to assessing and documenting HOBIC measures because of language barriers, patients' cognitive status and lack of time. Recommendations to improve uptake include developing, implementing and evaluating a communication and learning plan that promotes HOBIC's values and benefits, and determining how managers and administrators perceive utilization of HOBIC at the clinical unit and organizational levels. PMID:22469758

  15. Do Practicing Clinicians Agree with Expert Ratings of Neonatal Intensive Care Unit Quality Measures?

    PubMed Central

    Kowalkowski, Marc; Gould, Jeffrey B; Bose, Carl; Petersen, Laura A; Profit, Jochen

    2014-01-01

    Objective To assess the level of agreement when selecting quality measures for inclusion in a composite index of neonatal intensive care quality (Baby-MONITOR) between two panels: one comprised of academic researchers (Delphi) and another comprised of academic and clinical neonatologists (Clinician). Design/Methods In a modified Delphi process, a panel rated twenty eight quality measures. We assessed clinician agreement with the Delphi panel by surveying a sample of forty eight neonatal intensive care practitioners. We asked the clinician group to indicate their level of agreement with the Delphi panel for each measure using a five- point scale (much too high, slightly too high, reasonable, slightly too low, and much too low). In addition, we asked clinicians to select measures for inclusion in the Baby-MONITOR based on a yes or no vote and a pre-specified two-thirds majority for inclusion. Results Twenty three (47.9%) of the clinicians responded to the survey. We found high levels of agreement between the Delphi and clinician panels, particularly across measures selected for the Baby-MONITOR. Clinicians selected the same nine measures for inclusion in the composite as the Delphi panel. For these nine measures, 74% of clinicians indicated that the Delphi panel rating was ‘reasonable’. Conclusions Practicing clinicians agree with an expert panel on the measures that should be included in the Baby-MONITOR, enhancing face validity. PMID:22241483

  16. SU-E-T-257: Output Constancy: Reducing Measurement Variations in a Large Practice Group

    SciTech Connect

    Hedrick, K; Fitzgerald, T; Miller, R

    2014-06-01

    Purpose: To standardize output constancy check procedures in a large medical physics practice group covering multiple sites, in order to identify and reduce small systematic errors caused by differences in equipment and the procedures of multiple physicists. Methods: A standardized machine output constancy check for both photons and electrons was instituted within the practice group in 2010. After conducting annual TG-51 measurements in water and adjusting the linac to deliver 1.00 cGy/MU at Dmax, an acrylic phantom (comparable at all sites) and PTW farmer ion chamber are used to obtain monthly output constancy reference readings. From the collected charge reading, measurements of air pressure and temperature, and chamber Ndw and Pelec, a value we call the Kacrylic factor is determined, relating the chamber reading in acrylic to the dose in water with standard set-up conditions. This procedure easily allows for multiple equipment combinations to be used at any site. The Kacrylic factors and output results from all sites and machines are logged monthly in a central database and used to monitor trends in calibration and output. Results: The practice group consists of 19 sites, currently with 34 Varian and 8 Elekta linacs (24 Varian and 5 Elekta linacs in 2010). Over the past three years, the standard deviation of Kacrylic factors measured on all machines decreased by 20% for photons and high energy electrons as systematic errors were found and reduced. Low energy electrons showed very little change in the distribution of Kacrylic values. Small errors in linac beam data were found by investigating outlier Kacrylic values. Conclusion: While the use of acrylic phantoms introduces an additional source of error through small differences in depth and effective depth, the new standardized procedure eliminates potential sources of error from using many different phantoms and results in more consistent output constancy measurements.

  17. An evaluation of a new instrument to measure organisational safety culture values and practices.

    PubMed

    Díaz-Cabrera, D; Hernández-Fernaud, E; Isla-Díaz, R

    2007-11-01

    The main aim of this research is to evaluate a safety culture measuring instrument centred upon relevant organisational values and practices related to the safety management system. Seven dimensions that reflect underlying safety meanings are proposed. A second objective is to explore the four cultural orientations in the field of safety arising from the competing values framework. The study sample consisted of 299 participants from five companies in different sectors. The results show six dimensions of organisational values and practices and different company profiles in the organisations studied. The four cultural orientations proposed by the competing values framework are not confirmed. Nevertheless, a coexistence of diverse cultural orientations or paradoxes in the companies is observed. PMID:17920844

  18. Measuring sports injuries on the pitch: a guide to use in practice

    PubMed Central

    Hespanhol, Luiz C.; Barboza, Saulo D.; van Mechelen, Willem; Verhagen, Evert

    2015-01-01

    Sports participation is a major ally for the promotion of physical activity. However, sports injuries are important adverse effects of sports participation and should be monitored in sports populations. The purpose of this paper is to review the basic concepts of injury monitoring and discuss the implementation of these concepts in practice. The aspects discussed are: (1) sports injury definition; (2) classification of sports injuries; (3) population at risk, prevalence, and incidence; (4) severity measures; (5) economic costs; (6) systems developed to monitor sports injuries; and (7) online technology. Only with reliable monitoring systems applied in a continuous and long-term manner will it be possible to identify the burden of injuries, to identify the possible cases at an early stage, to implement early interventions, and to generate data for sports injury prevention. The implementation of sports injuries monitoring systems in practice is strongly recommended. PMID:26537807

  19. A Practically Validated Intelligent Calibration Circuit Using Optimized ANN for Flow Measurement by Venturi

    NASA Astrophysics Data System (ADS)

    Venkata, Santhosh Krishnan; Roy, Binoy Krishna

    2016-03-01

    Design of an intelligent flow measurement technique using venturi flow meter is reported in this paper. The objectives of the present work are: (1) to extend the linearity range of measurement to 100 % of full scale input range, (2) to make the measurement technique adaptive to variations in discharge coefficient, diameter ratio of venturi nozzle and pipe (β), liquid density, and liquid temperature, and (3) to achieve the objectives (1) and (2) using an optimized neural network. The output of venturi flow meter is differential pressure. It is converted to voltage by using a suitable data conversion unit. A suitable optimized artificial neural network (ANN) is added, in place of conventional calibration circuit. ANN is trained, tested with simulated data considering variations in discharge coefficient, diameter ratio between venturi nozzle and pipe, liquid density, and liquid temperature. The proposed technique is then subjected to practical data for validation. Results show that the proposed technique has fulfilled the objectives.

  20. A Bayesian semiparametric model for bivariate sparse longitudinal data.

    PubMed

    Das, Kiranmoy; Li, Runze; Sengupta, Subhajit; Wu, Rongling

    2013-09-30

    Mixed-effects models have recently become popular for analyzing sparse longitudinal data that arise naturally in biological, agricultural and biomedical studies. Traditional approaches assume independent residuals over time and explain the longitudinal dependence by random effects. However, when bivariate or multivariate traits are measured longitudinally, this fundamental assumption is likely to be violated because of intertrait dependence over time. We provide a more general framework where the dependence of the observations from the same subject over time is not assumed to be explained completely by the random effects of the model. We propose a novel, mixed model-based approach and estimate the error-covariance structure nonparametrically under a generalized linear model framework. We use penalized splines to model the general effect of time, and we consider a Dirichlet process mixture of normal prior for the random-effects distribution. We analyze blood pressure data from the Framingham Heart Study where body mass index, gender and time are treated as covariates. We compare our method with traditional methods including parametric modeling of the random effects and independent residual errors over time. We conduct extensive simulation studies to investigate the practical usefulness of the proposed method. The current approach is very helpful in analyzing bivariate irregular longitudinal traits. PMID:23553747

  1. Longitudinally-vibrating surgical microelectrode

    NASA Technical Reports Server (NTRS)

    Feldstein, C.; Crawford, D.; Kawabus, E. W.

    1977-01-01

    Microelectrode attached to cone of loudspeaker imparting longitudinal vibrations, penetrates relatively tough tissue of arterial walls easier and with more precise depth control because dimpling is eliminated. Vibrating microelectrode has been successfully used to make accurate oxygen-content measurements in arterial walls.

  2. Using relative survival measures for cross-sectional and longitudinal benchmarks of countries, states, and districts: the BenchRelSurv- and BenchRelSurvPlot-macros

    PubMed Central

    2013-01-01

    Background The objective of screening programs is to discover life threatening diseases in as many patients as early as possible and to increase the chance of survival. To be able to compare aspects of health care quality, methods are needed for benchmarking that allow comparisons on various health care levels (regional, national, and international). Objectives Applications and extensions of algorithms can be used to link the information on disease phases with relative survival rates and to consolidate them in composite measures. The application of the developed SAS-macros will give results for benchmarking of health care quality. Data examples for breast cancer care are given. Methods A reference scale (expected, E) must be defined at a time point at which all benchmark objects (observed, O) are measured. All indices are defined as O/E, whereby the extended standardized screening-index (eSSI), the standardized case-mix-index (SCI), the work-up-index (SWI), and the treatment-index (STI) address different health care aspects. The composite measures called overall-performance evaluation (OPE) and relative overall performance indices (ROPI) link the individual indices differently for cross-sectional or longitudinal analyses. Results Algorithms allow a time point and a time interval associated comparison of the benchmark objects in the indices eSSI, SCI, SWI, STI, OPE, and ROPI. Comparisons between countries, states and districts are possible. Exemplarily comparisons between two countries are made. The success of early detection and screening programs as well as clinical health care quality for breast cancer can be demonstrated while the population’s background mortality is concerned. Conclusions If external quality assurance programs and benchmark objects are based on population-based and corresponding demographic data, information of disease phase and relative survival rates can be combined to indices which offer approaches for comparative analyses between

  3. Measuring Limit-Setting Practices Used by Family Members Towards Relatives with Psychiatric Disorders.

    PubMed

    Labrum, Travis; Walk, Marlene; Solomon, Phyllis L

    2016-09-01

    Family members often set limits with relatives with psychiatric disorders (PD), however, no scale currently exists measuring the use of such limit-setting practices. The present article describes the development and results of a new measure, the Family Limit-Setting Scale (FLSS). Via a national online survey, the FLSS was completed by 573 adults residing in the U.S. who report having an adult relative with PD. We conducted exploratory and confirmatory factor analyses, examined internal consistencies and other indicators of construct validity, and performed invariance analyses assessing the generality of the optimal factor model to men, women, Caucasian respondents, and non-Caucasian respondents. Results indicate that the FLSS has an acceptable two factor structure (routine limit-setting and crisis prevention limit-setting) with both factors being highly generalizable to all groups of respondents examined. Internal consistencies and other indicators provide additional evidence of the FLSS' construct validity. Use of the FLSS will enable the conduction of quantitative research in this area. In addition, this measure may be employed in education/support organizations for families with a member with mental illness in an effort to identify persons using high levels of limit-setting practices who may benefit from extra support and/or guidance. PMID:26518780

  4. Technology transfer from biomedical research to clinical practice: measuring innovation performance.

    PubMed

    Balas, E Andrew; Elkin, Peter L

    2013-12-01

    Studies documented 17 years of transfer time from clinical trials to practice of care. Launched in 2002, the National Institutes of Health (NIH) translational research initiative needs to develop metrics for impact assessment. A recent White House report highlighted that research and development productivity is declining as a result of increased research spending while the new drugs output is flat. The goal of this study was to develop an expanded model of research-based innovation and performance thresholds of transfer from research to practice. Models for transfer of research to practice have been collected and reviewed. Subsequently, innovation pathways have been specified based on common characteristics. An integrated, intellectual property transfer model is described. The central but often disregarded role of research innovation disclosure is highlighted. Measures of research transfer and milestones of progress have been identified based on the Association of University Technology Managers 2012 performance reports. Numeric milestones of technology transfer are recommended at threshold (top 50%), target (top 25%), and stretch goal (top 10%) performance levels. Transfer measures and corresponding target levels include research spending to disclosure (<$1.88 million), disclosure to patents (>0.81), patents to start-up (>0.1), patents to licenses (>2.25), and average per license income (>$48,000). Several limitations of measurement are described. Academic institutions should take strategic steps to bring innovation to the center of scholarly discussions. Research on research, particularly on pathways to disclosures, is needed to improve R&D productivity. Researchers should be informed about the technology transfer performance of their institution and regulations should better support innovators. PMID:24142938

  5. LSTGEE: longitudinal analysis of neuroimaging data

    NASA Astrophysics Data System (ADS)

    Li, Yimei; Zhu, Hongtu; Chen, Yasheng; An, Hongyu; Gilmore, John; Lin, Weili; Shen, Dinggang

    2009-02-01

    Longitudinal imaging studies are essential to understanding the neural development of neuropsychiatric disorders, substance use disorders, and normal brain. Using appropriate image processing and statistical tools to analyze the imaging, behavioral, and clinical data is critical for optimally exploring and interpreting the findings from those imaging studies. However, the existing imaging processing and statistical methods for analyzing imaging longitudinal measures are primarily developed for cross-sectional neuroimaging studies. The simple use of these cross-sectional tools to longitudinal imaging studies will significantly decrease the statistical power of longitudinal studies in detecting subtle changes of imaging measures and the causal role of time-dependent covariate in disease process. The main objective of this paper is to develop longitudinal statistics toolbox, called LSTGEE, for the analysis of neuroimaging data from longitudinal studies. We develop generalized estimating equations for jointly modeling imaging measures with behavioral and clinical variables from longitudinal studies. We develop a test procedure based on a score test statistic and a resampling method to test linear hypotheses of unknown parameters, such as associations between brain structure and function and covariates of interest, such as IQ, age, gene, diagnostic groups, and severity of disease. We demonstrate the application of our statistical methods to the detection of the changes of the fractional anisotropy across time in a longitudinal neonate study. Particularly, our results demonstrate that the use of longitudinal statistics can dramatically increase the statistical power in detecting the changes of neuroimaging measures. The proposed approach can be applied to longitudinal data with multiple outcomes and accommodate incomplete and unbalanced data, i.e., subjects with different number of measurements.

  6. Phase shift errors in the theory and practice of surface intensity measurements

    NASA Technical Reports Server (NTRS)

    Mcgary, M. C.; Crocker, M. J.

    1982-01-01

    The surface acoustical intensity method (sometimes known as the microphone-accelerometer cross-spectral method) is a relatively new noise source/path identification tool. Several researchers have had difficulties implementing this method because of instrumentation phase mis-match. A simple technique for measuring and correcting instrumentation phase mis-match has been developed. This new technique has been tested recently on a noise source identification problem of practical interest. The results of the experiments indicate that the surface acoustic intensity method produces reliable data and can be applied to a variety of noise source/path problems.

  7. Making the decoy-state measurement-device-independent quantum key distribution practically useful

    NASA Astrophysics Data System (ADS)

    Zhou, Yi-Heng; Yu, Zong-Wen; Wang, Xiang-Bin

    2016-04-01

    The relatively low key rate seems to be the major barrier to its practical use for the decoy-state measurement-device-independent quantum key distribution (MDI-QKD). We present a four-intensity protocol for the decoy-state MDI-QKD that hugely raises the key rate, especially in the case in which the total data size is not large. Also, calculations show that our method makes it possible for secure private communication with fresh keys generated from MDI-QKD with a delay time of only a few seconds.

  8. Designing Chemistry Practice Exams for Enhanced Benefits. An Instrument for Comparing Performance and Mental Effort Measures

    NASA Astrophysics Data System (ADS)

    Knaus, Karen J.; Murphy, Kristen L.; Holme, Thomas A.

    2009-07-01

    The design and use of a chemistry practice exam instrument that includes a measure for student mental effort is described in this paper. Use of such an instrument can beneficial to chemistry students and chemistry educators as well as chemical education researchers from both a content and cognitive science perspective. The method for calculating and representing cognitive efficiency in different chemistry categories at both the student-level and classroom-level is described. In addition, explanation of the information available and potential benefits to each of the target populations is discussed with respect to instrument use.

  9. A Comparison of the Long-Term Learning Effects of Comprehensive and Topic-Specific Practice Set Assignments

    ERIC Educational Resources Information Center

    Fatemi, Darius; Marley, Robert; Marquis, Linda M.

    2015-01-01

    The authors examined the long-term learning effects of two different practice set assignment approaches on business students' long-term learning: a comprehensive, multiple-period practice set and a topic-specific practice set. Student learning was measured longitudinally across semesters. The authors found evidence that students using a…

  10. Replacing manual sphygmomanometers with automated blood pressure measurement in routine clinical practice.

    PubMed

    Myers, Martin G

    2014-01-01

    1. Conventional manual measurement of blood pressure (BP) in clinical practice is no longer considered to be the best method for evaluating a patient's BP status. Home BP and 24 h ambulatory BP monitoring are now recommended for the diagnosis and management of hypertension.  2. Recent studies provide an alternative to conventional office BP, namely automated office (AO) BP, which involves multiple BP readings taken with a fully automated device with the patient resting quietly alone. Automated office BP is preferable to routine manual office BP in that it exhibits improved accuracy and a stronger relationship to both ambulatory BP and target organ damage. 3. Having the patient alone eliminates conversation between the patient and the observer, a cause of 'white coat hypertension'. The use of an automated device improves accuracy, reduces digit preference, minimizes observer bias and facilitates the recording of multiple BP readings.  4. Comparative BP data obtained in clinical studies in both research settings and routine community practice support the use of a cut-off point of 135/85 mmHg for defining hypertension using AOBP, which is the same cut-off point currently recommended for awake ambulatory BP and home BP. 5. Reduction of the white coat response using AOBP should reduce the need to monitor patients with ambulatory BP and home BP after initiation of antihypertensive therapy. There is now sufficient evidence to consider replacing manual office BP with AOBP in routine clinical practice. PMID:23819734

  11. Field Measurements at River and Tidal Current Sites for Hydrokinetic Energy Development: Best Practices Manual

    SciTech Connect

    Neary, Vincent S; Gunawan, Budi

    2011-09-01

    In this report, existing data collection techniques and protocols for characterizing open channel flows are reviewed and refined to further address the needs of the MHK industry. The report provides an overview of the hydrodynamics of river and tidal channels, and the working principles of modern acoustic instrumentation, including best practices in remote sensing methods that can be applied to hydrokinetic energy site characterization. Emphasis is placed upon acoustic Doppler velocimeter (ADV) and acoustic-Doppler current profiler (ADCP) instruments, as these represent the most practical and economical tools for use in the MHK industry. Incorporating the best practices as found in the literature, including the parameters to be measured, the instruments to be deployed, the instrument deployment strategy, and data post-processing techniques. The data collected from this procedure aims to inform the hydro-mechanical design of MHK systems with respect to energy generation and structural loading, as well as provide reference hydrodynamics for environmental impact studies. The standard metrics and protocols defined herein can be utilized to guide field experiments with MHK systems.

  12. Patterns of treatment with PDE5 inhibitors in the clinical practice in Italy: longitudinal data from the Erectile Dysfunction Observational Study

    PubMed Central

    Fusco, Ferdinando; Sicuteri, Riccardo; Rossi, Andrea; Kontodimas, Stathis; Haro, Jose Maria; Imbimbo, Ciro

    2009-01-01

    The Erectile Dysfunction Observational Study (EDOS) is a 6-months observational prospective multicentric study enrolling men with erectile dysfunction (ED) who asked, to be started on a treatment or to change a previous treatment. Aims of the study were to analyse the pattern of treatment and compare the efficacy of treatments used. Patients were enrolled during a normal hospital visit and were prescribed a treatment for ED. They were asked at baseline and after 3 and 6 months, to answer a set of questions from the International Index of Erectile Function, Erectile Dysfunction Inventory of Treatment Satisfaction (EDITS) and Short Form of the Psychological and Interpersonal Relationships Scale questionnaires (SF-PAIRS). Clinicians were free to prescribe any therapy for ED available in the market, and to change therapy at any time during the study. Out of 1 338 patients, available for analysis at 6 months, 624 (47%) changed their treatment during the study and 714 (53%) continued with the drug prescribed at baseline. Patients assuming tadalafil had a significantly higher probability of maintaining the same treatment compared to sildenafil or vardenafil. There was no clinically significant difference in terms of efficacy, patient satisfaction, self-confidence and spontaneity between the different inhibitors of PDE5. The 'time concerns' domain score of SF-PAIRS, was statistically better in patients assuming tadalafil. In conclusion sildenafil, vardenafil and tadalafil show similar efficacy in the clinical practice. However, patients receiving tadalafil display a lower risk to discontinue or change the treatment. PMID:19701217

  13. Maternal and Adolescent Report of Mothers’ Weight-Related Concerns and Behaviors: Longitudinal Associations with Adolescent Body Dissatisfaction and Weight Control Practices

    PubMed Central

    Keery, Helene; Eisenberg, Marla; Neumark-Sztainer, Dianne

    2010-01-01

    Objective This population-based study examined mothers’ weight-related concerns and behaviors (weight status, weight dissatisfaction, dieting, and encouraging child to diet) at baseline, as assessed by both mothers and adolescents, and associations with adolescents’ body dissatisfaction and weight control practices 5 years later. Methods Adolescents and their mothers (n = 443 pairs) were surveyed in 1998–1999; adolescents were resurveyed in 2003–2004. Results Baseline maternal report of higher levels of her weight-related concerns/behaviors was associated with greater body dissatisfaction in girls 5 years later, controlling for adolescent weight status and other covariates. Baseline maternal report of weight-related concerns/behaviors was also associated with greater prevalence of trying to lose weight in both boys and girls 5 years later. Baseline adolescent report of higher maternal weight-related concerns/behaviors was associated with a higher prevalence of trying to lose weight 5 years later in girls. Conclusions These findings highlight the importance of mothers’ weight-related concerns and behaviors for adolescents’ weight-related outcomes. PMID:20498008

  14. A controlled statistical study to assess measurement variability as a function of test object position and configuration for automated surveillance in a multicenter longitudinal COPD study (SPIROMICS)

    PubMed Central

    Guo, Junfeng; Wang, Chao; Chan, Kung-Sik; Jin, Dakai; Saha, Punam K.; Sieren, Jered P.; Barr, R. G.; Han, MeiLan K.; Kazerooni, Ella; Cooper, Christopher B.; Couper, David; Hoffman, Eric A.

    2016-01-01

    Purpose: A test object (phantom) is an important tool to evaluate comparability and stability of CT scanners used in multicenter and longitudinal studies. However, there are many sources of error that can interfere with the test object-derived quantitative measurements. Here the authors investigated three major possible sources of operator error in the use of a test object employed to assess pulmonary density-related as well as airway-related metrics. Methods: Two kinds of experiments were carried out to assess measurement variability caused by imperfect scanning status. The first one consisted of three experiments. A COPDGene test object was scanned using a dual source multidetector computed tomographic scanner (Siemens Somatom Flash) with the Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS) inspiration protocol (120 kV, 110 mAs, pitch = 1, slice thickness = 0.75 mm, slice spacing = 0.5 mm) to evaluate the effects of tilt angle, water bottle offset, and air bubble size. After analysis of these results, a guideline was reached in order to achieve more reliable results for this test object. Next the authors applied the above findings to 2272 test object scans collected over 4 years as part of the SPIROMICS study. The authors compared changes of the data consistency before and after excluding the scans that failed to pass the guideline. Results: This study established the following limits for the test object: tilt index ≤0.3, water bottle offset limits of [−6.6 mm, 7.4 mm], and no air bubble within the water bottle, where tilt index is a measure incorporating two tilt angles around x- and y-axis. With 95% confidence, the density measurement variation for all five interested materials in the test object (acrylic, water, lung, inside air, and outside air) resulting from all three error sources can be limited to ±0.9 HU (summed in quadrature), when all the requirements are satisfied. The authors applied these criteria to 2272 SPIROMICS

  15. Procedural and practical applications of radiation measurements for BNCT at the HFR Petten

    NASA Astrophysics Data System (ADS)

    Moss, R. L.; Stecher-Rasmussen, F.; Rassow, J.; Morrissey, J.; Voorbraak, W.; Verbakel, W.; Appelman, K.; Daquino, G. G.; Muzi, L.; Wittig, A.; Bourhis-Martin, E.; Sauerwein, W.

    2004-01-01

    Since October 1997, a clinical trial of Boron Neutron Capture Therapy (BNCT) for glioblastoma patients has been in progress at the High Flux Reactor, Petten, the Netherlands. The trial is a European Organisation for Research and Treatment of Cancer (EORTC) protocol (#11 961) and, as such, must be conducted following the highest quality management and procedures, according to good clinical practice and also other internationally accepted codes. The complexity of BNCT involves not only strict international procedures, but also a variety of techniques to measure the different aspects of the irradiation involved when treating the patient. Applications include: free beam measurements using packets of activation foils; in-phantom measurements for beam calibration using ionisation chambers, pn-diodes and activation foils; monitoring of the irradiation beam during patient treatment using fission chambers and GM-counters; boron in blood measurements using prompt gamma ray spectroscopy; radiation protection of the patient and staff using portable radiation dosimeters and personal dosimeters; and in vivo measurements of the boron in the patient using a prompt gamma ray telescope. The procedures and applications of such techniques are presented here, with particular emphasis on the importance of the quality assurance/quality control procedures and its reporting.

  16. Quality-of-Life Measures for Cardiac Surgery Practice and Research: A Review and Primer

    PubMed Central

    Tully, Phillip J.

    2013-01-01

    Abstract: Declining mortality and major morbidity rates after cardiac surgery have led to increasing focus on patient quality of life (QOL). Beyond longevity, the impact of cardiac surgery on day-to-day functioning is incredibly salient to patients, their spouses, and families. As such, QOL measures are a welcome and sometimes necessary addition to clinical trials. However, how does one navigate the expansive market of QOL questionnaires, which QOL measures are applicable to cardiac surgery units, and how can they be used meaningfully in clinical practice? Because nearly two decades have passed since QOL measures were reviewed for relevance to cardiac surgery settings, an overview is provided of various generic (Short Form Health Survey [SF-36], Sickness Impact Profile, Nottingham Health Profile) and disease-specific QOL measures (Duke Activity Status Index, Seattle Angina Questionnaire, MN Living with Heart Failure Questionnaire; Heart-QOL) with examples from cardiac surgery studies. Recommendations are provided for the application of QOL measures to clinical trials and the impact on clinical decision-making is discussed. The paucity of methodologically sound QOL studies highlights the necessity for further rigorous empirical data to better inform treatment efficacy studies and clinical decision-making. PMID:23691778

  17. Knowledge, Attitude, and Practices Toward Blood Pressure Measurement at Home Among Japanese Nurses.

    PubMed

    Ishikuro, Mami; Ubeda, Sergio Ramón Gutiérrez; Obara, Taku; Watanabe, Ikue; Metoki, Hirohito; Kikuya, Masahiro; Kuriyama, Shinichi; Maruyama, Ryoko; Ohkubo, Takayoshi; Imai, Yutaka

    2016-04-01

    The self-measurement of blood pressure (BP) at home is useful in predicting the level of target organ damage and in managing hypertension. Nurses are essential practitioners for managing hypertension; however, it is unclear whether they have adequate knowledge of home BP management. This study assessed the knowledge, attitudes, and practices of home BP measurement among Japanese nurses. A questionnaire regarding home BP measurement was distributed among nurses and collected by mail. A total of 6,002 (61.8%) responses were eligible for the study. The proportion of participants who correctly recognized the reference values for clinic BP and home BP was 9.9% and 2.8%. Midwives and those working for the government had the highest proportion of correct responses of reference values among all nursing subgroups. Participants who thought that home BP gave the most important BP information were 62.7%. About 60% of the participants who recommended home BP measurement to hypertensive patients preferred to recommend an upper-arm cuff device. Our findings suggested that more knowledge of home BP measurement among nurses is warranted. PMID:27023297

  18. Measuring protein dynamics in live cells: protocols and practical considerations for fluorescence fluctuation microscopy

    PubMed Central

    Youker, Robert T.; Teng, Haibing

    2014-01-01

    Abstract. Quantitative analysis of protein complex stoichiometries and mobilities are critical for elucidating the mechanisms that regulate cellular pathways. Fluorescence fluctuation spectroscopy (FFS) techniques can measure protein dynamics, such as diffusion coefficients and formation of complexes, with extraordinary precision and sensitivity. Complete calibration and characterization of the microscope instrument is necessary in order to avoid artifacts during data acquisition and to capitalize on the full capabilities of FFS techniques. We provide an overview of the theory behind FFS techniques, discuss calibration procedures, provide protocols, and give practical considerations for performing FFS experiments. One important parameter recovered from FFS measurements is the relative molecular brightness that can correlate with oligomerization. Three methods for measuring molecular brightness (fluorescence correlation spectroscopy, photon-counting histogram, and number and brightness analysis) recover similar values when measuring samples under ideal conditions in vitro. However, examples are given illustrating that these different methods used for calculating molecular brightness of fluorescent molecules in cells are not always equivalent. Methods relying on spot measurements are more prone to bleaching and movement artifacts that can lead to underestimation of brightness values. We advocate for the use of multiple FFS techniques to study molecular brightnesses to overcome and compliment limitations of individual techniques. PMID:25260867

  19. Measuring Physical Activity: Practical Approaches for Program Evaluation in Native American Communities

    PubMed Central

    Sallis, James F.

    2010-01-01

    Promoting physical activity is a high priority in the United States, especially for Native American populations, due to very high rates of inactivity-related chronic diseases. High quality physical activity measures can contribute to achieving health goals. Measuring a sample of the population can identify high risk subgroups and geographic locations that can be targeted for interventions. Outcomes of physical activity interventions should be evaluated because this is the only way to determine whether they are effective. Three types of measures are practical for use in non-research settings, though they still present challenges. First, self-reports are commonly used; they are low-cost, but the least accurate. Second, objective monitors such as pedometers, accelerometers, and heart rate monitors can provide accurate information, but resources and expertise are needed to collect and manage the data. Third, direct observation can be used to evaluate school physical education programs and assess how people are using parks and other physical activity facilities. Studies of Native American populations have used a variety of measures. Good evaluations can lead to program improvements, documenting positive results can attract funding to continue and expand programs, and communicating results can persuade other communities to adopt effective approaches. Program evaluations using quality physical activity measures can contribute to achieving the goal of improved health in Native American communities. PMID:20689389

  20. Measuring physical activity: practical approaches for program evaluation in Native American communities.

    PubMed

    Sallis, James F

    2010-01-01

    Promoting physical activity is a high priority in the United States, especially for Native American populations, due to very high rates of inactivity-related chronic diseases. High-quality physical activity measures can contribute to achieving health goals. Measuring a sample of the population can identify high-risk subgroups and geographic locations that can be targeted for interventions. Outcomes of physical activity interventions should be evaluated because this is the only way to determine whether they are effective. Three types of measures are practical for use in nonresearch settings, although they still present challenges. First, self-reports are commonly used; they are low-cost but the least accurate. Second, objective monitors such as pedometers, accelerometers, and heart rate monitors can provide accurate information, but resources and expertise are needed to collect and manage data. Third, direct observation can be used to evaluate school physical education programs and assess how people are using parks and other physical activity facilities. Studies of Native American populations have used a variety of measures. Good evaluations can lead to program improvements, documenting positive results can attract funding to continue and expand programs, and communicating results can persuade other communities to adopt effective approaches. Program evaluations using quality physical activity measures can contribute to achieving the goal of improved health in Native American communities. PMID:20689389

  1. Investigating Long-Term Effects of Cochlear Implantation in Single-Sided Deafness: A Best Practice Model for Longitudinal Assessment of Spatial Hearing Abilities and Tinnitus Handicap

    PubMed Central

    Gartrell, Brian C.; Jones, Heath G.; Kan, Alan; Buhr-Lawler, Melanie; Gubbels, Samuel P.; Litovsky, Ruth Y.

    2015-01-01

    Objectives To evaluate methods for measuring long-term benefits of cochlear implantation in a patient with single-sided deafness (SSD) with respect to spatial hearing and to document improved quality of life due to reduced tinnitus. Patient A single adult male with profound right-sided sensorineural hearing loss and normal hearing in the left ear who underwent right-sided cochlear implantation. Methods The subject was evaluated at 6, 9, 12, and 18 months after implantation on speech intelligibility with specific target-masker configurations, sound localization accuracy, audiological performance, and tinnitus handicap. Testing conditions involved the acoustic (NH) ear only, the cochlear implant (CI) ear (acoustic ear plugged), and the bilateral condition (CI+NH). Measures of spatial hearing included speech intelligibility improvement due to spatial release from masking (SRM) and sound localization. In addition, traditional measures known as “head shadow,” “binaural squelch” and “binaural summation,” were evaluated. Results The best indicator for improved speech intelligibility was SRM, in which both ears are activated but the relative locations of target and masker(s) are manipulated. Measures that compare performance with a single ear to performance utilizing bilateral auditory input indicated evidence of the ability to integrate inputs across the ears, possibly reflecting early binaural processing, with 12 months of bilateral input. Sound localization accuracy improved with addition of the implant, and a large improvement with respect to tinnitus handicap was observed. Conclusions Cochlear implantation resulted in improved sound localization accuracy when compared to performance utilizing only the NH ear, and reduced tinnitus handicap was observed with use of the implant. The use of SRM addresses some of the current limitations of traditional measures of spatial and binaural hearing, as spatial cues related to target and maskers are manipulated, rather

  2. LONGITUDINAL LASER WIRE AT SNS

    SciTech Connect

    Aleksandrov, Alexander V; Liu, Yun; Zhukov, Alexander P

    2014-01-01

    This paper describes a longitudinal H- beam profile scanner that utilizes laser light to detach convoy electrons and an MCP to collect and measure these electrons. The scanner is located in MEBT with H- energy of 2.5MeV and an RF frequency 402.5MHz. The picosecond pulsed laser runs at 80.5MHz in sync with the accelerator RF. The laser beam is delivered to the beam line through a 30m optical fiber. The pulse width after the fiber transmission measures about 10ps. Scanning the laser phase effectively allows measurements to move along ion bunch longitudinal position. We are able to reliably measure production beam bunch length with this method. The biggest problem we have encountered is background signal from electrons being stripped by vacuum. Several techniques of signal detection are discussed.

  3. Indicators for assessing socioeconomic sustainability of bioenergy systems. A short list of practical measures

    SciTech Connect

    Dale, Virginia H.; Efroymson, Rebecca Ann; Kline, Keith L.; Langholtz, Matthew H.; Leiby, Paul Newsome; Oladosu, Gbadebo A.; Davis, Maggie R.; Downing, Mark E.; Hilliard, Michael R.

    2012-10-16

    Indicators are needed to assess both socioeconomic and environmental sustainability of bioenergy systems. Effective indicators can help to identify and quantify the sustainability attributes of bioenergy options. We identify 16 socioeconomic indicators that fall into the categories of social well-being, energy security, trade, profitability, resource conservation, and social acceptability. The suite of indicators is predicated on the existence of basic institutional frameworks to provide governance, legal, regulatory and enforcement services. Indicators were selected to be practical, sensitive to stresses, unambiguous, anticipatory, predictive, calibrated with known variability, and sufficient when considered collectively. The utility of each indicator, methods for its measurement, and applications appropriate for the context of particular bioenergy systems are described along with future research needs. Together, this suite of indicators is hypothesized to reflect major socioeconomic effects of the full supply chain for bioenergy, including feedstock production and logistics, conversion to biofuels, biofuel logistics and biofuel end uses. Ten of those 16 indicators are proposed to be the minimum list of practical measures of socioeconomic aspects of bioenergy sustainability. Coupled with locally-prioritized environmental indicators, we propose that these socioeconomic indicators can provide a basis to quantify and evaluate sustainability of bioenergy systems across many regions in which they will be deployed.

  4. Ability to Identify, Explain and Solve Problems in Everyday Tasks: Preliminary Validation of a Direct Video Measure of Practical Intelligence

    ERIC Educational Resources Information Center

    Yalon-Chamovitz, Shira; Greenspan, Stephen

    2005-01-01

    Recent developments in the definitional literature on mental retardation emphasize the need to ground the concept of adaptive behavior in an expanded model of intelligence, which includes practical and social intelligence. Development of a direct measure of practical intelligence might increase the likelihood that an assessment of this domain…

  5. Practical issues in ultrashort-laser-pulse measurement using frequency-resolved optical gating

    SciTech Connect

    DeLong, K.W.; Fittinghoff, D.N.; Trebino, R.

    1996-07-01

    The authors explore several practical experimental issues in measuring ultrashort laser pulses using the technique of frequency-resolved optical gating (FROG). They present a simple method for checking the consistency of experimentally measured FROG data with the independently measured spectrum and autocorrelation of the pulse. This method is a powerful way of discovering systematic errors in FROG experiments. They show how to determine the optimum sampling rate for FROG and show that this satisfies the Nyquist criterion for the laser pulse. They explore the low- and high-power limits to FROG and determine that femtojoule operation should be possible, while the effects of self-phase modulation limit the highest signal efficiency in FROG to 1%. They also show quantitatively that the temporal blurring due to a finite-thickness medium in single-shot geometries does not strongly limit the FROG technique. They explore the limiting time-bandwidth values that can be represented on a FROG trace of a given size. Finally, they report on a new measure of the FROG error that improves convergence in the presence of noise.

  6. Noise and measurement errors in a practical two-state quantum bit commitment protocol

    NASA Astrophysics Data System (ADS)

    Loura, Ricardo; Almeida, Álvaro J.; André, Paulo S.; Pinto, Armando N.; Mateus, Paulo; Paunković, Nikola

    2014-05-01

    We present a two-state practical quantum bit commitment protocol, the security of which is based on the current technological limitations, namely the nonexistence of either stable long-term quantum memories or nondemolition measurements. For an optical realization of the protocol, we model the errors, which occur due to the noise and equipment (source, fibers, and detectors) imperfections, accumulated during emission, transmission, and measurement of photons. The optical part is modeled as a combination of a depolarizing channel (white noise), unitary evolution (e.g., systematic rotation of the polarization axis of photons), and two other basis-dependent channels, namely the phase- and bit-flip channels. We analyze quantitatively the effects of noise using two common information-theoretic measures of probability distribution distinguishability: the fidelity and the relative entropy. In particular, we discuss the optimal cheating strategy and show that it is always advantageous for a cheating agent to add some amount of white noise—the particular effect not being present in standard quantum security protocols. We also analyze the protocol's security when the use of (im)perfect nondemolition measurements and noisy or bounded quantum memories is allowed. Finally, we discuss errors occurring due to a finite detector efficiency, dark counts, and imperfect single-photon sources, and we show that the effects are the same as those of standard quantum cryptography.

  7. Single Agent Antihypertensive Therapy and Orthostatic Blood Pressure Behaviour in Older Adults Using Beat-to-Beat Measurements: The Irish Longitudinal Study on Ageing

    PubMed Central

    Canney, Mark; O’Connell, Matthew D. L.; Murphy, Catriona M.; O’Leary, Neil; Little, Mark A.; O’Seaghdha, Conall M.; Kenny, Rose Anne

    2016-01-01

    Background Impaired blood pressure (BP) stabilisation after standing, defined using beat-to-beat measurements, has been shown to predict important health outcomes. We aimed to define the relationship between individual classes of antihypertensive agent and BP stabilisation among hypertensive older adults. Methods Cross-sectional analysis from The Irish Longitudinal Study on Ageing, a cohort study of Irish adults aged 50 years and over. Beat-to-beat BP was recorded in participants undergoing an active stand test. We defined grade 1 hypertension according to European Society of Cardiology criteria (systolic BP [SBP] 140-159mmHg ± diastolic BP [DBP] 90-99mmHg). Outcomes were: (i) initial orthostatic hypotension (IOH) (SBP drop ≥40mmHg ± DBP drop ≥20mmHg within 15 seconds [s] of standing accompanied by symptoms); (ii) sustained OH (SBP drop ≥20mmHg ± DBP drop ≥10mmHg from 60 to 110s inclusive); (iii) impaired BP stabilisation (SBP drop ≥20mmHg ± DBP drop ≥10mmHg at any 10s interval during the test). Outcomes were assessed using multivariable-adjusted logistic regression. Results A total of 536 hypertensive participants were receiving monotherapy with a renin-angiotensin-aldosterone-system inhibitor (n = 317, 59.1%), beta-blocker (n = 89, 16.6%), calcium channel blocker (n = 89, 16.6%) or diuretic (n = 41, 7.6%). A further 783 untreated participants met criteria for grade 1 hypertension. Beta-blockers were associated with increased odds of initial OH (OR 2.05, 95% CI 1.31–3.21) and sustained OH (OR 3.36, 95% CI 1.87–6.03) versus untreated grade 1 hypertension. Multivariable adjustment did not attenuate the results. Impaired BP stabilisation was evident at 20s (OR 2.59, 95% CI 1.58–4.25) and persisted at 110s (OR 2.90, 95% CI 1.64–5.11). No association was found between the other agents and any study outcome. Conclusion Beta-blocker monotherapy was associated with a >2-fold increased odds of initial OH and a >3-fold increased odds of sustained OH

  8. A measurement of. Delta. sigma. sub L (np), the difference between neutron-proton total cross sections in pure longitudinal spin states

    SciTech Connect

    Beddo, M.E.

    1990-10-01

    A measurement off {Delta}{sigma}{sub L}(np), the difference between neutron-proton total cross sections in pure longitudinal spin states, is described. The results will help determine the isospin-zero (I = 0) scattering amplitudes, which are not well known above laboratory energies of 500 MeV, whereas the isospin-one (I = 1) amplitudes are fairly well-determined to 1 GeV. Data points were taken at the Los Alamos Meson Physics Facility (LAMPF) at Los Alamos, New Mexico, for five neutron beam energies: 484, 568, 634,720 and 788 MeV; they are the first in this energy range. Polarized neutrons were produced by charge-exchange of polarized protons on a liquid deuterium target (LD{sub 2}). Large-volume neutron counters detected the neutrons that passed through a polarized proton target. The counters subtended a range of solid angles large enough to allow extrapolation of the scattered neutrons to 0{degree}. Two modifications to the LAMPF accelerator system which were made for this work are described. They included a beam buncher,'' which modified the normal rf-time structure of the proton beam and allowed for the selection of peak-energy neutrons by time-of-flight means, and a computerized beam steering program, which reduced systematic effects due to beam motion at the LD{sub 2} target. The experimental values of {Delta}{sigma}{sub L}(np) are found to be consistent with other np data, including preliminary data from SIN and Saclay, but not with some results from Argonne which used a polarized proton beam and a polarized deuteron target. The I = 0 component was extracted from {Delta}{sigma}{sub L}(np) using existing pp data (I = 1), with the unexpected result that {Delta}{sigma}{sub L}(I = 0) was found to be essentially identical in shape to {Delta}{sigma}{sub L}(I = 1). The significance of this is not yet understood.

  9. ADDHEALTH - NATIONAL LONGITUDINAL STUDY OF ADOLESCENT HEALTH

    EPA Science Inventory

    This study provides a comprehensive view of the health and health behaviors of adolescents and the antecedents - personal, interpersonal, familial, and environmental of these outcomes. The study features a longitudinal, multi-level design with independent measurement at the indiv...

  10. Twin-tube practical acoustic thermometry: theory and measurements up to 1000 °C

    NASA Astrophysics Data System (ADS)

    Sutton, G.; Edwards, G.; Veltcheva, R.; de Podesta, M.

    2015-08-01

    We present details of a Practical Acoustic Thermometer (PAT), in which temperature is inferred from measurements of the speed of sound along acoustic waveguides. We describe both the theory of operation, and measurements on three devices at temperatures up to 1000 °C. Because the relationship between the speed of sound in a simple gas and absolute temperature is well understood, the mean temperature along a tube may be estimated from measurements of the frequency-dependent propagation constant. A PAT device made from two tubes of different lengths allows the temperature measurement region to be localised, creating an instrument functionally similar to conventional contact thermometers. Three twin-tube PAT devices were constructed and tested. PAT-A, made of silica, served to validate the technique with differences between the acoustic thermometer and a reference thermocouple of less than 2 °C at temperatures in the range from 100 °C to 1000 °C. PAT-B and PAT-C were made of Inconel-600, potentially more suitable for use in harsh environments. The Inconel devices deviated from expected behaviour in a reproducible manner, which after calibration allowed measurements with errors of less than  ±1 °C in the range to 700 °C. No drift was observed up to 700 °C. The drift observed during prolonged exposure to higher temperatures is described and its likely causes discussed. In the longer term, similar technology may provide a means for the measurement of temperature in harsh environments such as those found in the nuclear industry.

  11. Measuring Energy Metabolism in the Mouse – Theoretical, Practical, and Analytical Considerations

    PubMed Central

    Speakman, John R.

    2012-01-01

    The mouse is one of the most important model organisms for understanding human genetic function and disease. This includes characterization of the factors that influence energy expenditure and dysregulation of energy balance leading to obesity and its sequelae. Measuring energy metabolism in the mouse presents a challenge because the animals are small, and in this respect it presents similar challenges to measuring energy demands in many other species of small mammal. This paper considers some theoretical, practical, and analytical considerations to be considered when measuring energy expenditure in mice. Theoretically total daily energy expenditure is comprised of several different components: basal or resting expenditure, physical activity, thermoregulation, and the thermic effect of food. Energy expenditure in mice is normally measured using open flow indirect calorimetry apparatus. Two types of system are available – one of which involves a single small Spartan chamber linked to a single analyzer, which is ideal for measuring the individual components of energy demand. The other type of system involves a large chamber which mimics the home cage environment and is generally configured with several chambers/analyzer. These latter systems are ideal for measuring total daily energy expenditure but at present do not allow accurate decomposition of the total expenditure into its components. The greatest analytical challenge for mouse expenditure data is how to account for body size differences between individuals. This has been a matter of some discussion for at least 120 years. The statistically most appropriate approach is to use analysis of covariance with individual aspects of body composition as independent predictors. PMID:23504620

  12. Measuring energy metabolism in the mouse - theoretical, practical, and analytical considerations.

    PubMed

    Speakman, John R

    2013-01-01

    The mouse is one of the most important model organisms for understanding human genetic function and disease. This includes characterization of the factors that influence energy expenditure and dysregulation of energy balance leading to obesity and its sequelae. Measuring energy metabolism in the mouse presents a challenge because the animals are small, and in this respect it presents similar challenges to measuring energy demands in many other species of small mammal. This paper considers some theoretical, practical, and analytical considerations to be considered when measuring energy expenditure in mice. Theoretically total daily energy expenditure is comprised of several different components: basal or resting expenditure, physical activity, thermoregulation, and the thermic effect of food. Energy expenditure in mice is normally measured using open flow indirect calorimetry apparatus. Two types of system are available - one of which involves a single small Spartan chamber linked to a single analyzer, which is ideal for measuring the individual components of energy demand. The other type of system involves a large chamber which mimics the home cage environment and is generally configured with several chambers/analyzer. These latter systems are ideal for measuring total daily energy expenditure but at present do not allow accurate decomposition of the total expenditure into its components. The greatest analytical challenge for mouse expenditure data is how to account for body size differences between individuals. This has been a matter of some discussion for at least 120 years. The statistically most appropriate approach is to use analysis of covariance with individual aspects of body composition as independent predictors. PMID:23504620

  13. Restoration of longitudinal images.

    PubMed

    Hu, Y; Frieden, B R

    1988-01-15

    In this paper, a method of restoring longitudinal images is developed. By using the transfer function for longitudinal objects, and inverse filtering, a longitudinal image may be restored. The Fourier theory and sampling theorems for transverse images cannot be used directly in the longitudinal case. A modification and reasonable approximation are introduced. We have numerically established a necessary relationship between just-resolved longitudinal separation (after inverse filtering), noise level, and the taking conditions of object distance and lens diameter. An empirical formula is also found to well-fit the computed results. This formula may be of use for designing optical systems which are to image longitudinal details, such as in robotics or microscopy. PMID:20523607

  14. A practical and theoretical definition of very small field size for radiotherapy output factor measurements

    SciTech Connect

    Charles, P. H. Crowe, S. B.; Langton, C. M.; Trapp, J. V.; Cranmer-Sargison, G.; Thwaites, D. I.; Kairn, T.; Knight, R. T.; Kenny, J.

    2014-04-15

    Purpose: This work introduces the concept of very small field size. Output factor (OPF) measurements at these field sizes require extremely careful experimental methodology including the measurement of dosimetric field size at the same time as each OPF measurement. Two quantifiable scientific definitions of the threshold of very small field size are presented. Methods: A practical definition was established by quantifying the effect that a 1 mm error in field size or detector position had on OPFs and setting acceptable uncertainties on OPF at 1%. Alternatively, for a theoretical definition of very small field size, the OPFs were separated into additional factors to investigate the specific effects of lateral electronic disequilibrium, photon scatter in the phantom, and source occlusion. The dominant effect was established and formed the basis of a theoretical definition of very small fields. Each factor was obtained using Monte Carlo simulations of a Varian iX linear accelerator for various square field sizes of side length from 4 to 100 mm, using a nominal photon energy of 6 MV. Results: According to the practical definition established in this project, field sizes ≤15 mm were considered to be very small for 6 MV beams for maximal field size uncertainties of 1 mm. If the acceptable uncertainty in the OPF was increased from 1.0% to 2.0%, or field size uncertainties are 0.5 mm, field sizes ≤12 mm were considered to be very small. Lateral electronic disequilibrium in the phantom was the dominant cause of change in OPF at very small field sizes. Thus the theoretical definition of very small field size coincided to the field size at which lateral electronic disequilibrium clearly caused a greater change in OPF than any other effects. This was found to occur at field sizes ≤12 mm. Source occlusion also caused a large change in OPF for field sizes ≤8 mm. Based on the results of this study, field sizes ≤12 mm were considered to be theoretically very small for 6

  15. Practical Immunoaffinity-Enrichment LC-MS for Measuring Protein Kinetics of Low-Abundance Proteins

    PubMed Central

    Lassman, Michael E.; McAvoy, Thomas; Lee, Anita Y.H.; Chappell, Derek; Wong, Oitak; Zhou, Haihong; Reyes-Soffer, Gissette; Ginsberg, Henry N.; Millar, John S.; Rader, Daniel J.; Gutstein, David E.; Laterza, Omar

    2016-01-01

    BACKGROUND For a more complete understanding of pharmacodynamic, metabolic, and pathophysiologic effects, protein kinetics, such as production rate and fractional catabolic rate, can offer substantially more information than protein concentration alone. Kinetic experiments with stable isotope tracers typically require laborious sample preparation and are most often used for studying abundant proteins. Here we describe a practical methodology for measuring isotope enrichment into low-abundance proteins that uses an automated procedure and immunoaffinity enrichment (IA) with LC-MS. Low-abundance plasma proteins cholesteryl ester transfer protein (CETP) and proprotein convertase subtilisin/kexin type 9 (PCSK9) were studied as examples. METHODS Human participants (n = 39) were infused with [2H3]leucine, and blood samples were collected at multiple time points. Sample preparation and analysis were automated and multiplexed to increase throughput. Proteins were concentrated from plasma by use of IA and digested with trypsin to yield proteotypic peptides that were analyzed by microflow chromatography-mass spectrometry to measure isotope enrichment. RESULTS The IA procedure was optimized to provide the greatest signal intensity. Use of a gel-free method increased throughput while increasing the signal. The intra- and interassay CVs were <15% at all isotope enrichment levels studied. More than 1400 samples were analyzed in <3 weeks without the need for instrument stoppages or user interventions. CONCLUSIONS The use of automated gel-free methods to multiplex the measurement of isotope enrichment was applied to the low-abundance proteins CETP and PCSK9. PMID:24751376

  16. Developing and pilot testing practical measures of preanalytic surgical specimen identification defects.

    PubMed

    Bixenstine, Paul J; Zarbo, Richard J; Holzmueller, Christine G; Yenokyan, Gayane; Robinson, Raymond; Hudson, Daniel W; Prescott, Arlene M; Hubble, Ron; Murphy, Mary M; George, Chris T; D'Angelo, Rita; Watson, Sam R; Lubomski, Lisa H; Berenholtz, Sean M

    2013-01-01

    Accurate patient identification is a National Patient Safety Goal. Misidentification of surgical specimens is associated with increased morbidity, mortality, and costs of care. The authors developed 12 practical, process-based, standardized measures of surgical specimen identification defects during the preanalytic phase of pathology testing (from the operating room to the surgical pathology laboratory) that could be used to quantify the occurrence of these defects. The measures (6 container and 6 requisition identification defects) were developed by a panel of physicians, pathologists, nurses, and quality experts. A total of 69 hospitals prospectively collected data over 3 months. Overall, there were identification defects in 2.9% of cases (1780/60 501; 95% confidence interval [CI] = 2.0%-4.4%), 1.2% of containers (1018/81 656; 95% CI = 0.8%-2.0%), and 2.3% of requisitions (1417/61 245; 95% CI = 1.2%-4.6%). Future research is needed to evaluate if hospitals are able to use these measures to assess interventions meant to reduce the frequency of specimen identification defects and improve patient safety. PMID:23322909

  17. Measuring Provider Attitudes Toward Evidence-Based Practice: Consideration of Organizational Context and Individual Differences

    PubMed Central

    Aarons, Gregory A.

    2006-01-01

    Mental health provider attitudes toward adoption of innovation in general, and toward evidence-based practice (EBP) in particular, are important in considering how best to disseminate and implement EBPs. This article first explores the role of attitudes in acceptance of innovation and proposes a model of organizational and individual factors that may affect or be affected by attitudes toward adoption of EBP. Next, a recently developed measure of mental health provider attitudes toward adoption of EBP is presented along with a summary of preliminary reliability and validity findings. Attitudes toward adoption of EBP are then discussed in regard to provider individual differences and the context of mental health services. Finally, potential applications of attitude research to adoption of EBP are discussed. PMID:15694785

  18. Using Project Performance to Measure Effectiveness of Quality Management System Maintenance and Practices in Construction Industry

    PubMed Central

    Leong, Tiong Kung; Ariff, Mohd. Shoki Md.

    2014-01-01

    This paper proposed seven existing and new performance indicators to measure the effectiveness of quality management system (QMS) maintenance and practices in construction industry. This research is carried out with a questionnaire based on QMS variables which are extracted from literature review and project performance indicators which are established from project management's theory. Data collected was analyzed using correlation and regression analysis. The findings indicate that client satisfaction and time variance have positive and significant relationship with QMS while other project performance indicators do not show significant results. Further studies can use the same project performance indicators to study the effectiveness of QMS in different sampling area to improve the generalizability of the findings. PMID:24701182

  19. Using project performance to measure effectiveness of quality management system maintenance and practices in construction industry.

    PubMed

    Leong, Tiong Kung; Zakuan, Norhayati; Mat Saman, Muhamad Zameri; Ariff, Mohd Shoki Md; Tan, Choy Soon

    2014-01-01

    This paper proposed seven existing and new performance indicators to measure the effectiveness of quality management system (QMS) maintenance and practices in construction industry. This research is carried out with a questionnaire based on QMS variables which are extracted from literature review and project performance indicators which are established from project management's theory. Data collected was analyzed using correlation and regression analysis. The findings indicate that client satisfaction and time variance have positive and significant relationship with QMS while other project performance indicators do not show significant results. Further studies can use the same project performance indicators to study the effectiveness of QMS in different sampling area to improve the generalizability of the findings. PMID:24701182

  20. A Measure of Person-Centered Practices in Assisted Living: The PC-PAL

    PubMed Central

    Zimmerman, Sheryl; Allen, Josh; Cohen, Lauren W.; Pinkowitz, Jackie; Reed, David; Coffey, Walter O.; Reed, Peter; Lepore, Michael; Sloane, Philip D.

    2014-01-01

    Objectives Develop self-administered questionnaires of person-centeredness for completion by residents and staff in assisted living (AL), in response to concerns that AL is not person-centered; also, demonstrated person-centeredness is necessary for Medicaid support as a home and community-based services provider. Design Community-based participatory research partnership between a research team, a consortium of 11 stakeholder organizations, and others. Methods included literature review, item generation and reduction, cognitive testing, field testing, exploratory factor analysis, and convergent and discriminant validity testing. Setting Cognitive testing conducted in two AL residences and field testing conducted in 19 diverse, stratified AL residences in six states. Participants Eight residents and staff participated in cognitive testing, and 228 residents and 123 staff participated in field testing. Measurements Feasibility and psychometric testing of draft questionnaires that included 75 items (resident version) and 102 items (staff version), with parallel items on both versions as appropriate. Results The final resident questionnaire included 49 items and four factors: well-being and belonging, individualized care and services, social connectedness, and atmosphere. The staff questionnaire included 62 items and five factors: workforce practices, social connectedness, individualized care and services, atmosphere, and caregiver-resident relationships. Staff scored person-centeredness higher than did residents, reflecting their different perspectives. Conclusion The Person-Centered Practices in Assisted Living (PC-PAL) questionnaires measure person-centeredness from the perspectives of residents and staff, meaning that they reflect the concepts and items considered to be important to these key stakeholders. Use of these instruments to describe, assess, quantify, assure, and ultimately improve person-centeredness in AL is feasible and appropriate for all AL settings

  1. Rasch Validation of a Measure of Reform-Oriented Science Teaching Practices

    NASA Astrophysics Data System (ADS)

    You, Hye Sun

    2016-04-01

    Growing evidence from recent curriculum documents and previous research suggests that reform-oriented science teaching practices promote students' conceptual understanding, levels of achievement, and motivation to learn, especially when students are actively engaged in constructing their ideas through scientific inquiries. However, it is difficult to identify to what extent science teachers engage students in reform-oriented teaching practices (RTPs) in their science classrooms. In order to exactly diagnose the current status of science teachers' implementation of the RTPs, a valid and reliable instrument tool is needed. The principles of validity and reliability are fundamental cornerstones in developing a robust measurement tool. As such, this study was motivated by the desire to point out the limitations of the existing statistical and psychometric analyses and to further examine the validation of the RTP survey instrument. This paper thus aims at calibrating the items of the RTPs for science teachers using the Rasch model. The survey instrument scale was adapted from the 2012 National Survey of Science and Mathematics Education (NSSME) data. A total of 3701 science teachers from 1403 schools from across the USA participated in the NSSME survey. After calibrating the RTP items and persons on the same scale, the RTP instrument well represented the population of US science teachers. Model-data fit determined by Infit and Outfit statistics was within an appropriate range (0.5-1.5), supporting the unidimensional structure of the RTPs. The ordered category thresholds and the probability of the thresholds showed that the five-point rating scale functioned well. The results of this study support the use of the RTP measure from the 2012 NSSME in assessing usage of RTPs.

  2. Rasch Validation of a Measure of Reform-Oriented Science Teaching Practices

    NASA Astrophysics Data System (ADS)

    You, Hye Sun

    2016-06-01

    Growing evidence from recent curriculum documents and previous research suggests that reform-oriented science teaching practices promote students' conceptual understanding, levels of achievement, and motivation to learn, especially when students are actively engaged in constructing their ideas through scientific inquiries. However, it is difficult to identify to what extent science teachers engage students in reform-oriented teaching practices (RTPs) in their science classrooms. In order to exactly diagnose the current status of science teachers' implementation of the RTPs, a valid and reliable instrument tool is needed. The principles of validity and reliability are fundamental cornerstones in developing a robust measurement tool. As such, this study was motivated by the desire to point out the limitations of the existing statistical and psychometric analyses and to further examine the validation of the RTP survey instrument. This paper thus aims at calibrating the items of the RTPs for science teachers using the Rasch model. The survey instrument scale was adapted from the 2012 National Survey of Science and Mathematics Education (NSSME) data. A total of 3701 science teachers from 1403 schools from across the USA participated in the NSSME survey. After calibrating the RTP items and persons on the same scale, the RTP instrument well represented the population of US science teachers. Model-data fit determined by Infit and Outfit statistics was within an appropriate range (0.5-1.5), supporting the unidimensional structure of the RTPs. The ordered category thresholds and the probability of the thresholds showed that the five-point rating scale functioned well. The results of this study support the use of the RTP measure from the 2012 NSSME in assessing usage of RTPs.

  3. Improving an electronic system for measuring PROs in routine oncology practice

    PubMed Central

    White, Sharon M.; Blackford, Amanda L.; Wolff, Antonio C.; Carducci, Michael A.; Herman, Joseph M.; Snyder, Claire F.

    2016-01-01

    Purpose Our aim was to study how patients and their clinicians evaluated the usability of PatientViewpoint, a webtool designed to allow patient-reported outcome (PRO) measures to be used in clinical practice. Methods As part of a two-round quality improvement study, breast and prostate cancer patients and their medical and radiation oncology clinicians completed semi-structured interviews about their use of PatientViewpoint. The patient interview addressed different phases of the PRO completion workflow: reminders, completing the survey, and viewing the results. The clinician interviews asked about use of PatientViewpoint, integration with the clinical workflow, barriers to use, and helpful and desired features. Responses were recorded, categorized, and reviewed. After both rounds of interviews, modifications were made to PatientViewpoint. Results Across the two rounds, 42 unique patients (n=19 in round 1, n=23 in round 2) and 12 clinicians (all in both rounds) completed interviews. For patients, median age was 65, 81% were white, 69% were college graduates, 80% had performance status of 0, 69% had loco-regional disease, and 81% were regular computer users. In the quality improvement interviews, patients identified numerous strengths of the system, including its ability to flag issues for discussion with their provider. Comments included confusion about how scores were presented and that the value of the system was diminished if the doctor did not look at the results. Requests included tailoring questions to be applicable to the individual and providing more explanation about the score meaning, including having higher scores consistently indicating either better or worse status. Clinicians also provided primarily positive feedback about the system, finding it helpful in some cases, and confirmatory in others. Their primary concern was with impact on their workflow. Conclusions Systematically collected feedback from patients and clinicians was useful to identify

  4. Longitudinal spin fluctuations in nickel

    SciTech Connect

    Boeni, P. , Villigen ); Martinez, J.L. ); Tranquada, J.M. )

    1989-10-10

    The longitudinal and transverse spin fluctuations in Ni have been measured below {Tc} by means of polarized neutron scattering in the momentum range 0.06 < q < 0.18 {angstrom}{sup -1}. In transverse scans spin wave peaks at E{sub q} = Dq{sup 2} appear as expected from early measurements performed with unpolarized neutrons. The longitudinal magnetic scattering {sub {chi}L}(q, E), on the other hand, is quasielastic without any signature of inelastic peaks near E{sub q}. The q and T dependences of {sub {chi}L}(q, E) resemble the paramagnetic scattering above {Tc}, i.e., the linewidth is roughly proportional to q{sup 2.5} and the integrated intensity I(q) is proportional to (q{sup 2} + {kappa}{sub z}{sup 2}){sup -1}. 8 refs., 3 figs.

  5. Bayesian response adaptive randomization using longitudinal outcomes.

    PubMed

    Hatayama, Tomoyoshi; Morita, Satoshi; Sakamaki, Kentaro

    2015-01-01

    The response adaptive randomization (RAR) method is used to increase the number of patients assigned to more efficacious treatment arms in clinical trials. In many trials evaluating longitudinal patient outcomes, RAR methods based only on the final measurement may not benefit significantly from RAR because of its delayed initiation. We propose a Bayesian RAR method to improve RAR performance by accounting for longitudinal patient outcomes (longitudinal RAR). We use a Bayesian linear mixed effects model to analyze longitudinal continuous patient outcomes for calculating a patient allocation probability. In addition, we aim to mitigate the loss of statistical power because of large patient allocation imbalances by embedding adjusters into the patient allocation probability calculation. Using extensive simulation we compared the operating characteristics of our proposed longitudinal RAR method with those of the RAR method based only on the final measurement and with an equal randomization method. Simulation results showed that our proposed longitudinal RAR method assigned more patients to the presumably superior treatment arm compared with the other two methods. In addition, the embedded adjuster effectively worked to prevent extreme patient allocation imbalances. However, our proposed method may not function adequately when the treatment effect difference is moderate or less, and still needs to be modified to deal with unexpectedly large departures from the presumed longitudinal data model. PMID:26099995

  6. Longitudinal Multistage Testing

    ERIC Educational Resources Information Center

    Pohl, Steffi

    2013-01-01

    This article introduces longitudinal multistage testing (lMST), a special form of multistage testing (MST), as a method for adaptive testing in longitudinal large-scale studies. In lMST designs, test forms of different difficulty levels are used, whereas the values on a pretest determine the routing to these test forms. Since lMST allows for…

  7. Integrating Sphere Finger-Photoplethysmography: Preliminary Investigation towards Practical Non-Invasive Measurement of Blood Constituents

    PubMed Central

    Matsumura, Kenta; Yamakoshi, Yasuhiro; Rolfe, Peter; Kiyohara, Daiki; Yamakoshi, Ken-ichi

    2015-01-01

    The aim of this study was to compare conventional photoplethysmography (PPG) in a finger with PPG using an integrating sphere (ISPPG) to enhance scattered light collection. Two representative wavelengths were used; 1160 nm, a window through the absorption spectra of water and alcohol, and 1600 nm around where water absorption is high and there is an absorption peak of blood glucose. Simultaneous transmission-type measurements were made with conventional PPG and with ISPPG for each wavelength in the tips of index fingers of both hands in a total of 10 healthy young male and female volunteers (21.7 ± 1.6 years old). During a 5 min period in which subjects were in a relaxed state we determined the signal-to-noise ratio, SNR, and the PPG detectability (or sensitivity) by the two techniques. SNR during the test period was significantly higher with ISPPG as compared with conventional PPG, especially for the 1600 nm wavelength. PPG signals with 1600 nm could scarcely be detected by conventional PPG, while they could be detected with good sensitively by ISPPG. We conclude that under controlled conditions ISPPG has better SNR and higher sensitivity than conventional transmission PPG, especially in wavelength regions where water absorption is high but where there is potential for practical measurement of blood constituents including glucose. PMID:26636974

  8. Practical quantum private query with better performance in resisting joint-measurement attack

    NASA Astrophysics Data System (ADS)

    Wei, Chun-Yan; Wang, Tian-Yin; Gao, Fei

    2016-04-01

    As a kind of practical protocol, quantum-key-distribution (QKD)-based quantum private queries (QPQs) have drawn lots of attention. However, joint-measurement (JM) attack poses a noticeable threat to the database security in such protocols. That is, by JM attack a malicious user can illegally elicit many more items from the database than the average amount an honest one can obtain. Taking Jacobi et al.'s protocol as an example, by JM attack a malicious user can obtain as many as 500 bits, instead of the expected 2.44 bits, from a 104-bit database in one query. It is a noticeable security flaw in theory, and would also arise in application with the development of quantum memories. To solve this problem, we propose a QPQ protocol based on a two-way QKD scheme, which behaves much better in resisting JM attack. Concretely, the user Alice cannot get more database items by conducting JM attack on the qubits because she has to send them back to Bob (the database holder) before knowing which of them should be jointly measured. Furthermore, JM attack by both Alice and Bob would be detected with certain probability, which is quite different from previous protocols. Moreover, our protocol retains the good characters of QKD-based QPQs, e.g., it is loss tolerant and robust against quantum memory attack.

  9. Array measurements adapted to the number of available sensors: Theoretical and practical approach for ESAC method

    NASA Astrophysics Data System (ADS)

    Galiana-Merino, J. J.; Rosa-Cintas, S.; Rosa-Herranz, J.; Garrido, J.; Peláez, J. A.; Martino, S.; Delgado, J.

    2016-05-01

    Array measurements of ambient noise have become a useful technique to estimate the surface wave dispersion curves and subsequently the subsurface elastic parameters that characterize the studied soil. One of the logistical handicaps associated with this kind of measurements is the requirement of several stations recording at the same time, which limits their applicability in the case of research groups without enough infrastructure resources. In this paper, we describe the theoretical basis of the ESAC method and we deduce how the number of stations needed to implement any array layout can be reduced to only two stations. In this way, we propose a new methodology to implement an N stations array layout by using only M stations (M < N), which will be recording in different positions of the original prearranged N stations geometry at different times. We also provide some practical guidelines to implement the proposed approach and we show different examples where the obtained results confirm the theoretical foundations. Thus, the study carried out reflects that we can use a minimum of 2 stations to deploy any array layout originally designed for higher number of sensors.

  10. Longitudinal bulk acoustic mass sensor

    SciTech Connect

    Hales, J. H.; Teva, J.; Boisen, A.; Davis, Z. J.

    2009-07-20

    A polycrystalline silicon longitudinal bulk acoustic cantilever is fabricated and operated in air at 51 MHz. A mass sensitivity of 100 Hz/fg (1 fg=10{sup -15} g) is obtained from the preliminary experiments where a minute mass is deposited on the device by means of focused ion beam. The total noise in the currently applied measurement system allows for a minimum detectable mass of 0.5 fg in air.

  11. Development of an Instrument to Measure Students' Attitudes towards Piano Practice

    ERIC Educational Resources Information Center

    Umuzdas, Mehmet Serkan

    2015-01-01

    Practicing the piano is a systematic part of the instrument-learning process. It contains all development practices from the analysis of the work to the improvement of performance. Students usually practice the piano as a preparation for performing in courses, exams, or on stage and they do it individually. The mentality which emerges during the…

  12. The ABCs of CBM: A Practical Guide to Curriculum-Based Measurement. Practical Intervention in the Schools Series

    ERIC Educational Resources Information Center

    Hosp, Michelle K.; Hosp, John L.; Howell, Kenneth W.

    2007-01-01

    This pragmatic, accessible book presents an empirically supported conceptual framework and hands-on instructions for conducting curriculum-based measurement (CBM) in grades K-8. The authors provide everything needed to evaluate student learning in reading, spelling, writing, and math; graph the resulting data; and use this information to make…

  13. A Practical Testing Battery to Measure Neurobehavioral Ability among Children with FASD

    PubMed Central

    Kalberg, Wendy O.; May, Philip A.; Blankenship, Jason; Buckley, David; Gossage, J. Phillip; Adnams, Colleen M.

    2014-01-01

    AIMS To determine a brief, practical battery of tests that discriminate between children with a fetal alcohol spectrum disorder (FASD) and unexposed controls. DESIGN Children received dysmorphology exams, a targeted battery of cognitive and behavioral tests, and their mothers were interviewed about maternal risk factors. Children diagnosed with an FASD and children unexposed to alcohol prenatally were compared on cognitive/behavioral test results. SETTING A community in The Western Cape Province of South Africa. PARTICIPANTS Sixty-one, first grade children with FASD and 52 matched normal controls. MEASURES Statistical analyses of maternal drinking behavior and their child's test performance. FINDINGS Self-reported maternal drinking patterns before during and after pregnancy were used to confirm prenatal exposures to alcohol in the group of children diagnosed with FASD. With this sample of children diagnosed with FASD and completely unexposed controls, the adverse effects of maternal drinking on children's performance are reported. Results of the battery of standardized cognitive and behavioral tests indicate highly significant differences (p ≤ .001) between groups on: intelligence, perceptual motor, planning, and logical, spatial, short term, long term, and working memory abilities. Furthermore, a binary logistical regression model of only 3 specific cognitive and behavioral tests, including Digit Span A+B (Wald = 4.10), Absurd Situation (Wald = 3.57), and Word Association (Wald = 4.30) correctly classified 79.1% of the child participants as FASD or controls. CONCLUSIONS A brief, practical set of tests can discriminate children with and without FASD and provide useful information for interventions for affected children. PMID:25258654

  14. Managing Organizational Commitment: Insights from Longitudinal Research

    ERIC Educational Resources Information Center

    Morrow, Paula C.

    2011-01-01

    This article summarizes what is known about the "active" management of affective organizational commitment (AOC) through a review of 58 studies employing longitudinal research designs. The review yields six broad categories of antecedents that have empirically demonstrated effects on AOC: socialization practices, organizational changes, human…

  15. Measuring mental health and wellbeing outcomes for children and adolescents to inform practice and policy: a review of child self-report measures.

    PubMed

    Deighton, Jessica; Croudace, Tim; Fonagy, Peter; Brown, Jeb; Patalay, Praveetha; Wolpert, Miranda

    2014-01-01

    There is a growing appetite for mental health and wellbeing outcome measures that can inform clinical practice at individual and service levels, including use for local and national benchmarking. Despite a varied literature on child mental health and wellbeing outcome measures that focus on psychometric properties alone, no reviews exist that appraise the availability of psychometric evidence and suitability for use in routine practice in child and adolescent mental health services (CAMHS) including key implementation issues. This paper aimed to present the findings of the first review that evaluates existing broadband measures of mental health and wellbeing outcomes in terms of these criteria. The following steps were implemented in order to select measures suitable for use in routine practice: literature database searches, consultation with stakeholders, application of inclusion and exclusion criteria, secondary searches and filtering. Subsequently, detailed reviews of the retained measures' psychometric properties and implementation features were carried out. 11 measures were identified as having potential for use in routine practice and meeting most of the key criteria: 1) Achenbach System of Empirically Based Assessment, 2) Beck Youth Inventories, 3) Behavior Assessment System for Children, 4) Behavioral and Emotional Rating Scale, 5) Child Health Questionnaire, 6) Child Symptom Inventories, 7) Health of the National Outcome Scale for Children and Adolescents, 8) Kidscreen, 9) Pediatric Symptom Checklist, 10) Strengths and Difficulties Questionnaire, 11) Youth Outcome Questionnaire. However, all existing measures identified had limitations as well as strengths. Furthermore, none had sufficient psychometric evidence available to demonstrate that they could reliably measure both severity and change over time in key groups. The review suggests a way of rigorously evaluating the growing number of broadband self-report mental health outcome measures against

  16. Decoupling control in velocity-varying four-wheel steering vehicles with H∞ performance by longitudinal velocity and yaw rate feedback

    NASA Astrophysics Data System (ADS)

    Li, Mingxing; Jia, Yingmin

    2014-12-01

    In this paper, decoupling control with H∞ performance for four-wheel steering (4WS) vehicles under varying longitudinal velocity is studied. A novel control scheme for a nonlinear model of three states, respectively, the longitudinal and lateral velocities, and yaw rate, is proposed to address this issue. The scheme is composed of two varying-parameter controllers designing problems for both longitudinal and lateral systems with coupling performance. Varying parameters of both these controllers depend only on longitudinal velocity. Controlled by these controllers, the longitudinal system is decoupled with lateral velocity and yaw rate, and the lateral system is input-output decoupling with H∞ performance. In addition, feedback signals are the longitudinal velocity and yaw rate, hence observations or measurements of lateral velocity are not necessary. Simulations show that vehicles controlled by our scheme are input-output diagonal decoupling and execute very well while longitudinal velocity varies in a large range, coupling appears between longitudinal and lateral systems, and external disturbances do exist. In summary, this control scheme can improve handling characteristics, safety and comfort proved from theory to practice in this paper.

  17. Office blood pressure measurement practices among community health providers (medical and paramedical) in northern district of India

    PubMed Central

    Mohan, Bishav; Aslam, Naved; Ralhan, Upma; Sharma, Sarit; Gupta, Naveen; Singh, Vivudh Pratap; Takkar, Shibba; Wander, G.S.

    2014-01-01

    Introduction Hypertension is directly responsible for 57% of all stroke deaths and 24% of all coronary heart disease deaths in India. Appropriate blood pressure measurement techniques are the cornerstone of clinical acumen. Despite the clear guidelines on BP measurement technique, there seems to be large inter-observer variations. Aim & methods A prospective, observational study was done to assess the knowledge and to study the current practices of office BP measurement among the 400 medical and paramedical staff working in various hospitals of a northern district of India. A single observer under the supervision of investigators observed all the participants and a proforma was filled based on AHA guidelines. After observing BP measurement technique scoring was done (≤8 question correct = inaccurate practices, >9 questions correct = accurate practices). Similarly, the knowledge was assessed by giving a pretested questionnaire. Results 5.85 % of the medical staff had excellent knowledge and 80% of the doctors and 62% of the paramedical staff had good knowledge about BPM. Only 1.47% (3 doctors) and 0.5% (1 nurse) had accurate practices. There was no correlation between knowledge and practices. Conclusions We conclude that the right technique and knowledge of blood pressure measurement among community health providers is inadequate and warrants further interventions to improve. PMID:25173197

  18. Measuring mental health and wellbeing outcomes for children and adolescents to inform practice and policy: a review of child self-report measures

    PubMed Central

    2014-01-01

    There is a growing appetite for mental health and wellbeing outcome measures that can inform clinical practice at individual and service levels, including use for local and national benchmarking. Despite a varied literature on child mental health and wellbeing outcome measures that focus on psychometric properties alone, no reviews exist that appraise the availability of psychometric evidence and suitability for use in routine practice in child and adolescent mental health services (CAMHS) including key implementation issues. This paper aimed to present the findings of the first review that evaluates existing broadband measures of mental health and wellbeing outcomes in terms of these criteria. The following steps were implemented in order to select measures suitable for use in routine practice: literature database searches, consultation with stakeholders, application of inclusion and exclusion criteria, secondary searches and filtering. Subsequently, detailed reviews of the retained measures’ psychometric properties and implementation features were carried out. 11 measures were identified as having potential for use in routine practice and meeting most of the key criteria: 1) Achenbach System of Empirically Based Assessment, 2) Beck Youth Inventories, 3) Behavior Assessment System for Children, 4) Behavioral and Emotional Rating Scale, 5) Child Health Questionnaire, 6) Child Symptom Inventories, 7) Health of the National Outcome Scale for Children and Adolescents, 8) Kidscreen, 9) Pediatric Symptom Checklist, 10) Strengths and Difficulties Questionnaire, 11) Youth Outcome Questionnaire. However, all existing measures identified had limitations as well as strengths. Furthermore, none had sufficient psychometric evidence available to demonstrate that they could reliably measure both severity and change over time in key groups. The review suggests a way of rigorously evaluating the growing number of broadband self-report mental health outcome measures against

  19. Semi-automatic handling of meteorological ground measurements using WeatherProg: prospects and practical implications

    NASA Astrophysics Data System (ADS)

    Langella, Giuliano; Basile, Angelo; Bonfante, Antonello; De Mascellis, Roberto; Manna, Piero; Terribile, Fabio

    2016-04-01

    WeatherProg is a computer program for the semi-automatic handling of data measured at ground stations within a climatic network. The program performs a set of tasks ranging from gathering raw point-based sensors measurements to the production of digital climatic maps. Originally the program was developed as the baseline asynchronous engine for the weather records management within the SOILCONSWEB Project (LIFE08 ENV/IT/000408), in which daily and hourly data where used to run water balance in the soil-plant-atmosphere continuum or pest simulation models. WeatherProg can be configured to automatically perform the following main operations: 1) data retrieval; 2) data decoding and ingestion into a database (e.g. SQL based); 3) data checking to recognize missing and anomalous values (using a set of differently combined checks including logical, climatological, spatial, temporal and persistence checks); 4) infilling of data flagged as missing or anomalous (deterministic or statistical methods); 5) spatial interpolation based on alternative/comparative methods such as inverse distance weighting, iterative regression kriging, and a weighted least squares regression (based on physiography), using an approach similar to PRISM. 6) data ingestion into a geodatabase (e.g. PostgreSQL+PostGIS or rasdaman). There is an increasing demand for digital climatic maps both for research and development (there is a gap between the major of scientific modelling approaches that requires digital climate maps and the gauged measurements) and for practical applications (e.g. the need to improve the management of weather records which in turn raises the support provided to farmers). The demand is particularly burdensome considering the requirement to handle climatic data at the daily (e.g. in the soil hydrological modelling) or even at the hourly time step (e.g. risk modelling in phytopathology). The key advantage of WeatherProg is the ability to perform all the required operations and

  20. Statistical image analysis of longitudinal RAVENS images

    PubMed Central

    Lee, Seonjoo; Zipunnikov, Vadim; Reich, Daniel S.; Pham, Dzung L.

    2015-01-01

    Regional analysis of volumes examined in normalized space (RAVENS) are transformation images used in the study of brain morphometry. In this paper, RAVENS images are analyzed using a longitudinal variant of voxel-based morphometry (VBM) and longitudinal functional principal component analysis (LFPCA) for high-dimensional images. We demonstrate that the latter overcomes the limitations of standard longitudinal VBM analyses, which does not separate registration errors from other longitudinal changes and baseline patterns. This is especially important in contexts where longitudinal changes are only a small fraction of the overall observed variability, which is typical in normal aging and many chronic diseases. Our simulation study shows that LFPCA effectively separates registration error from baseline and longitudinal signals of interest by decomposing RAVENS images measured at multiple visits into three components: a subject-specific imaging random intercept that quantifies the cross-sectional variability, a subject-specific imaging slope that quantifies the irreversible changes over multiple visits, and a subject-visit specific imaging deviation. We describe strategies to identify baseline/longitudinal variation and registration errors combined with covariates of interest. Our analysis suggests that specific regional brain atrophy and ventricular enlargement are associated with multiple sclerosis (MS) disease progression. PMID:26539071

  1. Practical decoy-state measurement-device-independent quantum key distribution

    NASA Astrophysics Data System (ADS)

    Sun, Shi-Hai; Gao, Ming; Li, Chun-Yan; Liang, Lin-Mei

    2013-05-01

    Measurement-device-independent quantum key distribution (MDI-QKD) is immune to all the detection attacks; thus when it is combined with the decoy-state method, the final key is unconditionally secure, even if a practical weak coherent source is used by Alice and Bob. However, until now, the analysis of decoy-state MDI-QKD with a weak coherent source is incomplete. In this paper, we derive, with only vacuum+weak decoy state, some tight formulas to estimate the lower bound of yield and the upper bound of error rate for the fraction of signals in which both Alice and Bob send a single-photon pulse to the untrusted third party Charlie. The numerical simulations show that our method with only vacuum+weak decoy state can asymptotically approach the theoretical limit of the infinite number of decoy states. Furthermore, the statistical fluctuation due to the finite length of date is also considered based on the standard statistical analysis.

  2. Management of children's fever by parents and caregivers: Practical measurement of functional health literacy.

    PubMed

    Emmerton, Lynne; Chaw, Xin Yao; Kelly, Fiona; Kairuz, Therese; Marriott, Jennifer; Wheeler, Amanda; Moles, Rebekah

    2014-12-01

    Functional health literacy is founded on general and numerical literacy and practical skills and is required for the appropriate and effective management of health symptoms in children. This study aimed to assess the health literacy skills of parents and caregivers of preschool-aged children, using a progressive scenario describing a child with fever and presenting tasks relating to selection of a medicine and hypothetical dosing of their child. Participants (n = 417) from 33 childcare- and health-related sites in Sydney, Brisbane, Melbourne and Auckland completed the study. Participants' responses were largely appropriate regarding actions in response to worsening symptoms, selection of an appropriate product (from a limited range), whereby 84.5% of responses were for a single-ingredient paracetamol product and use of the package directions to state the frequency of dosing (93.1% of frequencies appropriate for paracetamol and 66.7% for ibuprofen). However, in only 50.8% of cases was an appropriate weight-based dose calculated, and doses were not measured to within 10% of the stated dose in 16.7% of cases. Future studies should focus on skill development via educational campaigns for parents and caregivers. PMID:23908369

  3. Measurement of the parity-violating longitudinal single-spin asymmetry for W± boson production in polarized proton-proton collisions at sqrt[s] = 500 GeV.

    PubMed

    Aggarwal, M M; Ahammed, Z; Alakhverdyants, A V; Alekseev, I; Alford, J; Anderson, B D; Anson, C D; Arkhipkin, D; Averichev, G S; Balewski, J; Beavis, D R; Bellwied, R; Betancourt, M J; Betts, R R; Bhasin, A; Bhati, A K; Bichsel, H; Bielcik, J; Bielcikova, J; Biritz, B; Bland, L C; Borowski, W; Bouchet, J; Braidot, E; Brandin, A V; Bridgeman, A; Brovko, S G; Bruna, E; Bueltmann, S; Bunzarov, I; Burton, T P; Cai, X Z; Caines, H; Calderón de la Barca Sánchez, M; Cebra, D; Cendejas, R; Cervantes, M C; Chajecki, Z; Chaloupka, P; Chattopadhyay, S; Chen, H F; Chen, J H; Chen, J Y; Cheng, J; Cherney, M; Chikanian, A; Choi, K E; Christie, W; Chung, P; Codrington, M J M; Corliss, R; Cramer, J G; Crawford, H J; Dash, S; Davila Leyva, A; De Silva, L C; Debbe, R R; Dedovich, T G; Derevschikov, A A; Derradi de Souza, R; Didenko, L; Djawotho, P; Dogra, S M; Dong, X; Drachenberg, J L; Draper, J E; Dunlop, J C; Dutta Mazumdar, M R; Efimov, L G; Elnimr, M; Engelage, J; Eppley, G; Erazmus, B; Estienne, M; Eun, L; Evdokimov, O; Fatemi, R; Fedorisin, J; Fersch, R G; Finch, E; Fine, V; Fisyak, Y; Gagliardi, C A; Gangadharan, D R; Ganti, M S; Geromitsos, A; Geurts, F; Ghosh, P; Gorbunov, Y N; Gordon, A; Grebenyuk, O; Grosnick, D; Guertin, S M; Gupta, A; Guryn, W; Haag, B; Hamed, A; Han, L-X; Harris, J W; Hays-Wehle, J P; Heinz, M; Heppelmann, S; Hirsch, A; Hjort, E; Hoffmann, G W; Hofman, D J; Huang, B; Huang, H Z; Humanic, T J; Huo, L; Igo, G; Jacobs, P; Jacobs, W W; Jena, C; Jin, F; Joseph, J; Judd, E G; Kabana, S; Kang, K; Kapitan, J; Kauder, K; Keane, D; Kechechyan, A; Kettler, D; Kikola, D P; Kiryluk, J; Kisiel, A; Kizka, V; Klein, S R; Knospe, A G; Kocoloski, A; Koetke, D D; Kollegger, T; Konzer, J; Koralt, I; Koroleva, L; Korsch, W; Kotchenda, L; Kouchpil, V; Kravtsov, P; Krueger, K; Krus, M; Kumar, L; Kurnadi, P; Lamont, M A C; Landgraf, J M; LaPointe, S; Lauret, J; Lebedev, A; Lednicky, R; Lee, C-H; Lee, J H; Leight, W; LeVine, M J; Li, C; Li, L; Li, N; Li, W; Li, X; Li, X; Li, Y; Li, Z M; Lisa, M A; Liu, F; Liu, H; Liu, J; Ljubicic, T; Llope, W J; Longacre, R S; Love, W A; Lu, Y; Lukashov, E V; Luo, X; Ma, G L; Ma, Y G; Mahapatra, D P; Majka, R; Mall, O I; Mangotra, L K; Manweiler, R; Margetis, S; Markert, C; Masui, H; Matis, H S; Matulenko, Yu A; McDonald, D; McShane, T S; Meschanin, A; Milner, R; Minaev, N G; Mioduszewski, S; Mischke, A; Mitrovski, M K; Mohanty, B; Mondal, M M; Morozov, B; Morozov, D A; Munhoz, M G; Naglis, M; Nandi, B K; Nayak, T K; Netrakanti, P K; Ng, M J; Nogach, L V; Nurushev, S B; Odyniec, G; Ogawa, A; Ohlson, A; Okorokov, V; Oldag, E W; Olson, D; Pachr, M; Page, B S; Pal, S K; Pandit, Y; Panebratsev, Y; Pawlak, T; Peitzmann, T; Perkins, C; Peryt, W; Phatak, S C; Pile, P; Planinic, M; Ploskon, M A; Pluta, J; Plyku, D; Poljak, N; Poskanzer, A M; Potukuchi, B V K S; Powell, C B; Prindle, D; Pruneau, C; Pruthi, N K; Pujahari, P R; Putschke, J; Qiu, H; Raniwala, R; Raniwala, S; Ray, R L; Redwine, R; Reed, R; Ritter, H G; Roberts, J B; Rogachevskiy, O V; Romero, J L; Rose, A; Ruan, L; Sakai, S; Sakrejda, I; Sakuma, T; Salur, S; Sandweiss, J; Sangaline, E; Schambach, J; Scharenberg, R P; Schmah, A M; Schmitz, N; Schuster, T R; Seele, J; Seger, J; Selyuzhenkov, I; Seyboth, P; Shahaliev, E; Shao, M; Sharma, M; Shi, S S; Sichtermann, E P; Simon, F; Singaraju, R N; Skoby, M J; Smirnov, N; Sorensen, P; Spinka, H M; Srivastava, B; Stanislaus, T D S; Staszak, D; Stevens, J R; Stock, R; Strikhanov, M; Stringfellow, B; Suaide, A A P; Suarez, M C; Subba, N L; Sumbera, M; Sun, X M; Sun, Y; Sun, Z; Surrow, B; Svirida, D N; Symons, T J M; Szanto de Toledo, A; Takahashi, J; Tang, A H; Tang, Z; Tarini, L H; Tarnowsky, T; Thein, D; Thomas, J H; Tian, J; Timmins, A R; Timoshenko, S; Tlusty, D; Tokarev, M; Trainor, T A; Tram, V N; Trentalange, S; Tribble, R E; Tsai, O D; Ullrich, T; Underwood, D G; Van Buren, G; van Leeuwen, M; van Nieuwenhuizen, G; Vanfossen, J A; Varma, R; Vasconcelos, G M S; Vasiliev, A N; Videbæk, F; Viyogi, Y P; Vokal, S; Voloshin, S A; Wada, M; Walker, M; Wang, F; Wang, G; Wang, H; Wang, J S; Wang, Q; Wang, X L; Wang, Y; Webb, G; Webb, J C; Westfall, G D; Whitten, C; Wieman, H; Wissink, S W; Witt, R; Wu, Y F; Xie, W; Xu, H; Xu, N; Xu, Q H; Xu, W; Xu, Y; Xu, Z; Xue, L; Yang, Y; Yepes, P; Yip, K; Yoo, I-K; Yue, Q; Zawisza, M; Zbroszczyk, H; Zhan, W; Zhang, J B; Zhang, S; Zhang, W M; Zhang, X P; Zhang, Y; Zhang, Z P; Zhao, J; Zhong, C; Zhou, W; Zhu, X; Zhu, Y H; Zoulkarneev, R; Zoulkarneeva, Y

    2011-02-11

    We report the first measurement of the parity-violating single-spin asymmetries for midrapidity decay positrons and electrons from W+ and W- boson production in longitudinally polarized proton-proton collisions at sqrt[s] = 500 GeV by the STAR experiment at RHIC. The measured asymmetries, A(L)(W+) = -0.27 ± 0.10(stat.) ± 0.02(syst.) ± 0.03(norm.) and A(L)(W-) = 0.14 ± 0.19(stat.) ± 0.02(syst.) ± 0.01(norm.), are consistent with theory predictions, which are large and of opposite sign. These predictions are based on polarized quark and antiquark distribution functions constrained by polarized deep-inelastic scattering measurements. PMID:21405460

  4. Practice and applications of 17-O-excess measurements of water using novel laser spectroscopy

    NASA Astrophysics Data System (ADS)

    Dennis, K. J.; Steig, E. J.; Vasileios, G.; Schauer, A. J.; Schoenemann, S. W.; Hoffnagle, J.

    2014-12-01

    17O-excess, defined as the deviation from the Global Meteoric Water Line (GMWL) in a plot of ln(δ18O+1) vs. ln(δ17O+1), is an evolving tool for understanding the modern water cycle and reconstructing past climate regimes. Because of competing effects between equilibrium and kinetic fractionation small variations in 17O-excess can be used, for example, to (i) infer changes in temperature and sea ice across glacial-interglacial cycles in Antarctica (Schoenemann et al., 2014), (ii) study the role of rain re-evaporation during convective events thereby improving the incorporation of isotopes into GCMs (Landais et al., 2010), and (iii) assess the role of stratospheric water vapor intrusions at high altitudes or in polar regions (Winkler et al., 2013). In natural waters, variability in 17O-excess is very small (on the order of tens of per meg, where 1 per meg is 0.001‰). Until recently, only measurements made via Isotope Ratio Mass Spectrometry (IRMS) could achieve the required precision, following time-consuming front-end chemistry that converted H2O into O2 for analysis of m/z+ 32, 33 and 34. Recent improvements in laser-based spectroscopy, e.g., Cavity Ring-Down Spectroscopy (CRDS), are enabling quicker and easier measurement of 17O-excess in water (Steig et al., 2013; 2014). The Picarro L2140-i is certified with a precision of ≤ 0.015‰; however implementation of best practices can result in an achievable precision of ≤ 0.008‰, thereby demonstrating comparable performance to IRMS. We will review our recommendations for achieving high-precision measurements of 17O-excess on the Picarro L2140-i, including how to calibrate the system, the frequency of standards analysis, the number of replicate injections and vials required, and approaches to dealing with sample-to-sample memory. We will also compare the external accuracy achieved by three distinct Picarro L2140-i analyzers for multiple waters with distinct isotopic composition.

  5. Matching Familiar Figures Test; Technical Report II. Disadvantaged Children and Their First School Experiences. ETS-Head Start Longitudinal Study. Technical Report Series.

    ERIC Educational Resources Information Center

    Ward, William C.

    The Matching Familiar Figures Test is a measure of the response style "reflection-impulsivity." The version of the test used in the longitudinal study test battery consists of two practice and 18 test items. On each item, the child is shown one standard and four comparison figures. Figures are simple line drawings done in black on a white…

  6. Predicting time to prostate cancer recurrence based on joint models for non-linear longitudinal biomarkers and event time outcomes.

    PubMed

    Pauler, Donna K; Finkelstein, Dianne M

    2002-12-30

    Biological markers that are both sensitive and specific for tumour regrowth or metastasis are increasingly becoming available and routinely monitored during the regular follow-up of patients treated for cancer. Obtained by a simple blood test, these markers provide an inexpensive non-invasive means for the early detection of recurrence (or progression). Currently, the longitudinal behaviour of the marker is viewed as an indicator of early disease progression, and is applied by a physician in making clinical decisions. One marker that has been studied for use in both population screening for early disease and for detection of recurrence in prostate cancer patients is PSA. The elevation of PSA levels is known to precede clinically detectable recurrence by 2 to 5 years, and current clinical practice often relies partially on multiple recent rises in PSA to trigger a change in treatment. However, the longitudinal trajectory for individual markers is often non-linear; in many cases there is a decline immediately following radiation therapy or surgery, a plateau during remission, followed by an exponential rise following the recurrence of the cancer. The aim of this article is to determine the multiple aspects of the longitudinal PSA biomarker trajectory that can be most sensitive for predicting time to clinical recurrence. Joint Bayesian models for the longitudinal measures and event times are utilized based on non-linear hierarchical models, implied by unknown change-points, for the longitudinal trajectories, and a Cox proportional hazard model for progression times, with functionals of the longitudinal parameters as covariates in the Cox model. Using Markov chain Monte Carlo sampling schemes, the joint model is fit to longitudinal PSA measures from 676 patients treated at Massachusetts General Hospital between the years 1988 and 1995 with follow-up to 1999. Based on these data, predictive schemes for detecting cancer recurrence in new patients based on their

  7. The barriers and facilitators to routine outcome measurement by allied health professionals in practice: a systematic review

    PubMed Central

    2012-01-01

    Background Allied Health Professionals today are required, more than ever before, to demonstrate their impact. However, despite at least 20 years of expectation, many services fail to deliver routine outcome measurement in practice. This systematic review investigates what helps and hinders routine outcome measurement of allied health professionals practice. Methods A systematic review protocol was developed comprising: a defined search strategy for PsycINFO, MEDLINE and CINHAL databases and inclusion criteria and systematic procedures for data extraction and quality appraisal. Studies were included if they were published in English and investigated facilitators and/or barriers to routine outcome measurement by allied health professionals. No restrictions were placed on publication type, design, country, or year of publication. Reference lists of included publications were searched to identify additional papers. Descriptive methods were used to synthesise the findings. Results 960 papers were retrieved; 15 met the inclusion criteria. Professional groups represented were Physiotherapy, Occupational Therapy, and Speech and Language Therapy. The included literature varied in quality and design. Facilitators and barriers to routine outcome measurement exist at individual, managerial and organisational levels. Key factors affecting professionals’ use of routine outcome measurement include: professionals’ level of knowledge and confidence about using outcome measures, and the degree of organisational and peer-support professionals received with a view to promoting their work in practice. Conclusions Whilst the importance of routinely measuring outcomes within the allied health professions is well recognised, it has largely failed to be delivered in practice. Factors that influence clinicians’ ability and desire to undertake routine outcome measurement are bi-directional: they can act as either facilitators or barriers. Routine outcome measurement may only be

  8. Longitudinal Excitons in GaN

    NASA Astrophysics Data System (ADS)

    Reynolds, D. C.; Jogai, B.; Collins, T. C.

    2002-05-01

    Many of the previous investigations of longitudinal excitons have involved reflection and absorption measurements rather than emission. In these measurements it is more difficult to resolve the longitudinal exciton from the Γ5 and Γ6 free excitons in wurtzite material. The longitudinal excitons have energies and oscillator strengths that depend on the direction of propagation and they are not observable along the principal axis of the crystal. In the wurtzite structure, such as GaN, the Γ5 exciton is the pure transverse mode, whereas the longitudinal is a mixed mode going from pure longitudinal, for the propogation direction K perpendicular to C, to pure transverse for K parallel to C. If more than one orientation is present in the sample, it is clear that more than one longitudinal exciton may be seen since it is a mixed mode. In the current experiment we observe more than one mode, which we associate with more than one crystal orientation. This may result from the columnar growth often observed in GaN.

  9. Longitudinal relations between child vagal tone and parenting behavior: 2 to 4 years.

    PubMed

    Kennedy, Amy E; Rubin, Kenneth H; Hastings, Paul D; Maisel, Beth

    2004-07-01

    The longitudinal relations between physiological markers of child emotion regulation and maternal parenting practices were examined from 2 to 4 years of age. At Time 1, cardiac vagal tone was assessed for one hundred four 2-year-olds (54 females); their mothers completed an assessment of parenting styles. Two years later, at Time 2, 84 of the original participants were reassessed on measures of cardiac vagal tone and parenting style. Results indicated both baseline cardiac vagal tone and maternal parenting practices to be stable from 2 to 4 years of age. Children's cardiac vagal tone predicted specific parenting practices from the toddler to preschool years. Further, child cardiac vagal tone moderated maternal restrictive-parenting practices from 2 to 4 years of age; mothers of children who were highly or moderately physiologically dysregulated were more likely to report restrictive parenting practices at both 2 and 4 years of age. PMID:15229872

  10. Technical and practical issues for tidal breathing measurements of nasal nitric oxide in children.

    PubMed

    Beydon, Nicole; Chambellan, Arnaud; Alberti, Corinne; de Blic, Jacques; Clément, Annick; Escudier, Estelle; Le Bourgeois, Muriel

    2015-12-01

    To promote early screening of patients with suspected Primary Ciliary Dyskinesia (PCD), nasal nitric oxide (nNO) measurements during tidal breathing (TB) have been developed for children unable to ensure velum closure (VC) during breath hold or expiration against resistance. To investigate technical and practical issues related to TB-nNO methods in children referred for suspected or asserted PCD, we recorded, in a prospective multicenter study, TB-nNO (calculated as the mean of 5 peaks, 10 or 30 sec during tidal breathing) and VC-nNO when available. We studied 142 children (PCD diagnosis asserted in 47, excluded in 39). Nasal NO values were significantly different according to methods, VC-nNO being higher than TB-nNO (TB-nNO 5 peaks higher than mean of 10 or 30 sec). Specificity (90-94%) and sensitivity (86-97%) were similar between TB-nNO and VC-nNO methods. Age was more correlated with VC-nNO than with TB-nNO. TB-nNO could differ between the two nostrils by more than 10% (or 10 ppb when nNO absolute value lower 100 ppb) in 32-43% of the tested children, according to the different tidal breathing values, and was reproducible in the long term but influenced by ambient NO. Despite TB-nNO values being lower than VC-nNO, TB-nNO was found to be as discriminant for PCD, and probably more discriminant in children less than 8 years old, as the VC method. These results were obtained using the chemiluminescence technique which allows an easier assessment of relevant factors such as nasal permeability and ambient NO than the electrochemical technique. PMID:25731630

  11. Using theory and evidence to drive measurement of patient, nurse and organizational outcomes of professional nursing practice.

    PubMed

    Jeffs, Lianne; Sidani, Souraya; Rose, Donald; Espin, Sherry; Smith, Orla; Martin, Kirsten; Byer, Charlie; Fu, Kaiyan; Ferris, Ella

    2013-04-01

    An evolving body of literature suggests that the implementation of evidence based clinical and professional guidelines and strategies can improve patient care. However, gaps exist in our understanding of the effect of implementation of guidelines on outcomes, particularly patient outcomes. To address this gap, a measurement framework was developed to assess the impact of an organization-wide implementation of two nursing-centric best-practice guidelines on patient, nurse and organizational level outcomes. From an implementation standpoint, we anticipate that our data will show improvements in the following: (i) patient satisfaction scores and safety outcomes; (ii) nurses ability to value and engage in evidence based practice; and (iii) organizational support for evidence-informed nursing care that results in quality patient outcomes. Our measurement framework and multifaceted methodological approach outlined in this paper might serve as a blueprint for other organizations in their efforts to evaluate the impacts associated with implementation of clinical and professional guidelines and best practices. PMID:23577971

  12. The Development and Initial Validation of Social Cognitive Career Theory Instruments to Measure Choice of Medical Specialty and Practice Location

    ERIC Educational Resources Information Center

    Rogers, Mary E.; Creed, Peter A.; Searle, Judy

    2009-01-01

    Social cognitive career theory served as the basis for the instrument development for scales assessing self-efficacy, outcome expectations, and goals to predict medical career choice. Lent and Brown's conceptualization of social cognitive constructs guided the development of items to measure choice of medical specialty and practice location. Study…

  13. Reliability and Validity of a Questionnaire to Measure Consumer Knowledge regarding Safe Practices to Prevent Microbiological Contamination in Restaurants

    ERIC Educational Resources Information Center

    Uggioni, Paula Lazzarin; Salay, Elisabette

    2013-01-01

    Objective: The objective of this study was to develop a validated and reliable questionnaire to measure consumer knowledge regarding safe practices to prevent microbiological contamination in restaurants and commercial kitchens. Methods: Non-probabilistic samples of individuals were interviewed in the city of Campinas, Brazil. Questionnaire items…

  14. Theoretical and practical knowledge of Nursing professionals on indirect blood pressure measurement at a coronary care unit

    PubMed Central

    Machado, Juliana Pereira; Veiga, Eugenia Velludo; Ferreira, Paulo Alexandre Camargo; Martins, José Carlos Amado; Daniel, Ana Carolina Queiroz Godoy; Oliveira, Amanda dos Santos; da Silva, Patrícia Costa dos Santos

    2014-01-01

    Objective To determine and to analyze the theoretical and practical knowledge of Nursing professionals on indirect blood pressure measurement. Methods This cross-sectional study included 31 professionals of a coronary care unit (86% of the Nursing staff in the unit). Of these, 38.7% of professionals were nurses and 61.3% nurse technicians. A validated questionnaire was used to theoretical evaluation and for practice assessment the auscultatory technique was applied in a simulation environment, under a non-participant observation. Results To the theoretical knowledge of the stages of preparation of patient and environment, 12.9% mentioned 5-minute of rest, 48.4% checked calibration, and 29.0% chose adequate cuff width. A total of 64.5% of professionals avoided rounding values, and 22.6% mentioned the 6-month deadline period for the equipment calibration. On average, in practice assessment, 65% of the steps were followed. Lacks in knowledge were primary concerning lack of checking the device calibration and stethoscope, measurement of arm circumference to choose the cuff size, and the record of arm used in blood pressure measurement. Conclusion Knowledge was poor and had disparities between theory and practice with evidence of steps taken without proper awareness and lack of consideration of important knowledge during implementation of blood pressure measurement. Educational and operational interventions should be applied systematically with institutional involvement to ensure safe care with reliable values. PMID:25295455

  15. Measuring Teacher Self-Report on Classroom Practices: Construct Validity and Reliability of the Classroom Strategies Scale-Teacher Form

    ERIC Educational Resources Information Center

    Reddy, Linda A.; Dudek, Christopher M.; Fabiano, Gregory A.; Peters, Stephanie

    2015-01-01

    This article presents information about the construct validity and reliability of a new teacher self-report measure of classroom instructional and behavioral practices (the Classroom Strategies Scales-Teacher Form; CSS-T). The theoretical underpinnings and empirical basis for the instructional and behavioral management scales are presented.…

  16. Modifying the System for Observing Fitness Instruction Time to Measure Teacher Practices Related to Physical Activity Promotion: SOFIT+

    ERIC Educational Resources Information Center

    Weaver, R. Glenn; Webster, Collin A.; Erwin, Heather; Beighle, Aaron; Beets, Michael W.; Choukroun, Hadrien; Kaysing, Nicole

    2016-01-01

    The System for Observing Fitness Instruction Time (SOFIT) is commonly used to measure variables related to physical activity during physical education (PE). However, SOFIT does not yield detailed information about teacher practices related to children's moderate-to-vigorous physical activity (MVPA). This study describes the modification of SOFIT…

  17. Measuring Ultraviolet Radiation Underwater: A Practical Application of the Beer-Lambert-Bouguer Law for High School Physics

    ERIC Educational Resources Information Center

    Schouten, Peter; Parisi, Alfio; Downs, Nathan

    2009-01-01

    The measurement of solar UV under water is not a simple process. In the underwater environment the difficulty of obtaining useable data is greatly amplified due to the optically complicated and at times unpredictable nature of water itself. The following practical exercise designed for use in the Year 11 and Year 12 Physics classroom aims to…

  18. The Development of a Measure of Self-Regulated Practice Behavior for Beginning and Intermediate Instrumental Music Students

    ERIC Educational Resources Information Center

    Miksza, Peter

    2012-01-01

    The purpose of this study was to develop and test the construct validity and reliability of a self-report measure of self-regulated practice behaviors for beginning and intermediate instrumentalists. A questionnaire was designed to assess the motive, method, behavior, time management, and social influences dimensions of the theoretical model of…

  19. Historical View of the Influences of Measurement and Writing Theories on the Practice of Writing Assessment in the United States

    ERIC Educational Resources Information Center

    Behizadeh, Nadia; Engelhard, George, Jr.

    2011-01-01

    The purpose of this study is to examine the interactions among measurement theories, writing theories, and writing assessments in the United States from an historical perspective. The assessment of writing provides a useful framework for examining how theories influence, and in some cases fail to influence actual practice. Two research traditions…

  20. Measuring the effect of patient comfort rounds on practice environment and patient satisfaction: a pilot study.

    PubMed

    Gardner, Glenn; Woollett, Kaylene; Daly, Naomi; Richardson, Bronwyn

    2009-08-01

    Hourly rounding in the acute hospital setting has been proposed as an intervention to increase patient satisfaction and safety, and improve the nursing practice environment, but the innovation has not been adequately tested. A quasi-experimental pretest post-test non-randomized parallel group trial design was used to test the effect of hourly patient comfort rounds on patient satisfaction and nursing perceptions of the practice environment, and to evaluate research processes and instruments for a proposed larger study. A Patient Satisfaction Survey instrument was developed and used in conjunction with the Practice Environment Scale of the Nursing Work Index. Results on patient satisfaction showed no significant changes. Significant changes were found for three of the five practice environment subscales. Consistent with the aim of a pilot study, this research has provided important information related to design, instruments and process that will inform a larger sufficiently powered study. PMID:19703045

  1. Survivor-Defined Practice in Domestic Violence Work: Measure Development and Preliminary Evidence of Link to Empowerment.

    PubMed

    Goodman, Lisa A; Thomas, Kristie; Cattaneo, Lauren Bennett; Heimel, Deborah; Woulfe, Julie; Chong, Siu Kwan

    2016-01-01

    Survivor-defined practice, characterized by an emphasis on client choice, partnership, and sensitivity to the unique needs, contexts, and coping strategies of individual survivors, is an aspirational goal of the domestic violence (DV) movement, assumed to be a key contributor to empowerment and other positive outcomes among survivors. Despite its central role in DV program philosophy, training, and practice, however, our ability to assess its presence and its presumed link to well-being has been hampered by the absence of a way to measure it from survivors' perspectives. As part of a larger university-community collaboration, this study had two aims: (a) to develop a measure of survivor-defined practice from the perspective of participants, and (b) to assess its relationship to safety-related empowerment after controlling for other contributors to survivor well-being (e.g., financial stability and social support). Results supported the reliability and validity of the Survivor-Defined Practice Scale (SDPS), a nine-item measure that assesses participants' perception of the degree to which their advocates help them achieve goals they set for themselves, facilitate a spirit of partnership, and show sensitivity to their individual needs and styles. The items combined to form one factor indicating that the three theoretical aspects of survivor-defined practice may be different manifestations of one underlying construct. Results also support the hypothesized link between survivor-defined practice and safety-related empowerment. The SDPS offers DV programs a mechanism for process evaluation that is rigorous and rooted in the feminist empowerment philosophy that so many programs espouse. PMID:25381271

  2. Measurement of Longitudinal Single Spin Asymmetry in the Production of Muons from W/Z Boson Decays in Polarized p+p Collisions at sqrt s = 510 GeV with the PHENIX Detector at RHIC

    NASA Astrophysics Data System (ADS)

    Meles, Abraham

    The contribution from the sea quarks to the proton spin have been poorly constrained mainly because of the limited knowledge we have on the fragmentation function in polarized Semi Inclusive Deep Inelastic Scattering (SIDIS) experiments. The parity-violating longitudinal single spin asymmetry AL in the production of W bosons in p + p collisions does not involve fragmentation function and is an alternative better way of exploring the polarization of sea quarks in the proton. The measurement will be useful especially in constraining u and d¯ in the very backward and forward rapidities respectively. However, identifying the muons from the decay of the W is challenging due to a great background of hadronic in flight decays and other muon producing processes such as heavy flavor decays. In the forward and backward hemispheres of PHENIX at RHIC, the muon spectrometers have been recently upgraded in order to provide additional trigger and tracking information to suppress those backgrounds. One of those upgrades is the Forward Vertex (FVTX) detector, a silicon-strip tracker. In 2013, PHENIX accumulated the largest amount of polarized p + p collision data ever collected in the world (˜ 240pb--1 ) at s = 510 GeV with a beam polarization of 56%. The analysis techniques used to extract the signal from the data and the longitudinal single spin asymmetries AL in RHIC 2013 run will be discussed.

  3. A practical approach for measurement of antihypertensive medication adherence in patients with resistant hypertension.

    PubMed

    Corrêa, Nathália Batista; de Faria, Ana Paula; Ritter, Alessandra M V; Sabbatini, Andrea Rodrigues; Almeida, Aurélio; Brunelli, Veridiana; Calhoun, David A; Moreno, Heitor; Modolo, Rodrigo

    2016-06-01

    Confirmation of medication adherence is a challenge in clinical practice and essential for the accurate diagnosis of resistant hypertension. Although it is well established that drug adherence is critical for controlling blood pressure, there are still difficulties applying a simple, inexpensive, and reliable assessment of adherence in the clinical setting. We aimed to test a simple method to assess adherence in resistant hypertensive (RH) patients. A pilot study with normotensives or mild/moderate hypertensive subjects was performed to provide a fluorescence cutoff point for adherence. After that, 21 patients referred to the Resistant Hypertension Clinic had triamterene prescribed and were monitored for a 30-day period. We conducted two unannounced randomly selected home visits for urine collection to test drug intake that day. Office, home and 24-hour ambulatory blood pressure, biochemical data, and the 8-item Morisky Medication Adherence Scale (MMAS-8) were systematically acquired. According to adherence indicated by urine fluorescence, subjects were divided into adherent and nonadherent groups. We found 57% of nonadherence. No differences were found between groups regarding baseline characteristics or prescribed medications; Kappa's test showed concordance between adherence through MMAS-8 items and fluorescence (kappa = 0.61; 95% confidence interval: 0.28-0.94; P = .005). Nonadherent patients had higher office (81 ± 11 vs. 73 ± 6 mm Hg, P = .03), 24-hour ambulatory blood pressure monitoring (75 ± 9 vs. 66 ± 7 mm Hg, P = .01), and home blood pressure measurement (77 ± 9 vs. 67 ± 8 mm Hg, P = .01) diastolic blood pressure than their counterparts. Nonadherence to antihypertensive therapy is high in patients with RH, even when assessed in clinics specialized in this condition. Fluorometry to detect a drug in the urine of RH patients is safe, easy, and reliable method to assess adherence. PMID:27161936

  4. Flight Measurements of Flying Qualities of a P-47D-30 Airplane (AAF No. 43-3441) to Determine Longitudinal Stability and Control and Stalling Characteristics

    NASA Technical Reports Server (NTRS)

    Kraft, Christopher C., Jr.; Goranson, R. Fabien; Reeder, John P.

    1948-01-01

    Flight tests have been made to determine the longitudinal stability and control and stalling characteristics of the P-47.E-30 airplane. The teat results show the airplane to be unstable stick free in any power-on condition even at the most forward center-of-gravity position tested. At the rearward center-of-gravity position tested the airplane also had neutral to negative stick-fixed stability with power on. The characteristics in accelerated flight were acceptable at the forward center-of-gravity position at low and high altitudes except at high speed where the control-force variations with acceleration were high. At the rearward center-of-gravity position, elevator-force reversals were experienced in turns at low speeds, and the force per g was low at all the other speeds. Ample stall warning was afforded in all the conditions tested and the stalling characteristics were very satisfactory except in the approach and wave-off conditions.

  5. Longitudinal in vivo evaluation of bone regeneration by combined measurement of multi-pinhole SPECT and micro-CT for tissue engineering

    NASA Astrophysics Data System (ADS)

    Lienemann, Philipp S.; Metzger, Stéphanie; Kiveliö, Anna-Sofia; Blanc, Alain; Papageorgiou, Panagiota; Astolfo, Alberto; Pinzer, Bernd R.; Cinelli, Paolo; Weber, Franz E.; Schibli, Roger; Béhé, Martin; Ehrbar, Martin

    2015-05-01

    Over the last decades, great strides were made in the development of novel implants for the treatment of bone defects. The increasing versatility and complexity of these implant designs request for concurrent advances in means to assess in vivo the course of induced bone formation in preclinical models. Since its discovery, micro-computed tomography (micro-CT) has excelled as powerful high-resolution technique for non-invasive assessment of newly formed bone tissue. However, micro-CT fails to provide spatiotemporal information on biological processes ongoing during bone regeneration. Conversely, due to the versatile applicability and cost-effectiveness, single photon emission computed tomography (SPECT) would be an ideal technique for assessing such biological processes with high sensitivity and for nuclear imaging comparably high resolution (<1 mm). Herein, we employ modular designed poly(ethylene glycol)-based hydrogels that release bone morphogenetic protein to guide the healing of critical sized calvarial bone defects. By combined in vivo longitudinal multi-pinhole SPECT and micro-CT evaluations we determine the spatiotemporal course of bone formation and remodeling within this synthetic hydrogel implant. End point evaluations by high resolution micro-CT and histological evaluation confirm the value of this approach to follow and optimize bone-inducing biomaterials.

  6. Leading Horses to Water: Lessons from a Decade of Helping Psychological Therapy Services Use Routine Outcome Measurement to Improve Practice.

    PubMed

    Mellor-Clark, John; Cross, Simone; Macdonald, James; Skjulsvik, Tommy

    2016-05-01

    We summarise the recent reflections of five thought leaders in the field of routine outcome measurement (ROM) for psychological therapy, and then add our own experience of introducing a national ROM system in the UK. We highlight, in particular, the post-implementation challenge of securing data of sufficient reliability to help inform service quality improvements. We ground our conclusions and recommendations in the rapidly evolving discipline of implementation science, and offer a best practice model for applying research recommendations in practice settings. In this context we portray ROM implementation as significant organizational change that benefits from rigorous process and clearly defined, well-communicated targets. PMID:25179755

  7. Computational and Genomic Analysis of Mycobacteriophage: A Longitudinal Study of Technology Engineered Biology Courses That Implemented an Inquiry Based Laboratory Practice Designed to Enhance, Encourage, and Empower Student Learning

    ERIC Educational Resources Information Center

    Hollowell, Gail P.; Osler, James E.; Hester, April L.

    2015-01-01

    This paper provides an applied research rational for a longitudinal investigation that involved teaching a "Technology Engineered Science Education Course" via an Interactive Laboratory Based Genomics Curriculum. The Technology st Engineering [TE] methodology was first introduced at the SAPES: South Atlantic Philosophy of Education…

  8. Perturbative harmonic modulation of longitudinal electron-spin magnetization for short T1 determination

    NASA Astrophysics Data System (ADS)

    Suzuki, Takayuki

    2015-10-01

    Longitudinally detected T1 measurement scheme (LOD-T1) is studied in detail. In contrast to the original work on LOD-T1, using high power microwave pulses, this work deals with general and practically frequent cases in which perfect inversion of the electron-spin magnetization is not feasible due to the effect of relaxation during microwave pulses. Theoretical studies, numerical simulations, and experiments reveal a pair of separate contributions of the dynamics of the longitudinal magnetization to the LOD signal, namely, the periodic modulation and the relaxation contributions. The latter alone which is of interest can be extracted to give relaxation curves. In addition, it is shown that T1 information can be obtained even when the available microwave power is so low that the electron magnetization can only be perturbatively modulated, at the cost of reduced sensitivity. To overcome this, a modified pulse sequence is proposed. In this new method, the pulse excitations are repeated during half a period of the resonance of the longitudinal detection circuit. The method is called the perturbative harmonic modulation method for longitudinally detected T1 measurement (HM-LOD-T1). HM-LOD-T1 experiments are demonstrated in 2,2-diphenyl-1-picrylhydrazyl (DPPH).

  9. Stress, satisfaction and militancy among Canadian physicians: a longitudinal investigation.

    PubMed

    Burke, R J

    1996-08-01

    The introduction of a national health care system in Canada has resulted in regular and increasing conflict between the medical profession, government and other political actors. The present longitudinal study utilizes a stressor-strain framework to understand physician militancy in Canada. Data were collected from 1298 men and women physicians at two points in time separated by 4-5 years using questionnaires completed anonymously. Four groups of predictor variables identified in previous research were considered: individual demographic characteristics, practice characteristics, work stressors and work and professional satisfactions. Empirical support for the model was found. Each panel of predictor variables had significant and unique relationships with most measures of physician militancy measured 4-5 years later. PMID:8844952

  10. Cross-Level Measurement Invariance in School and Classroom Environment Surveys: Implications for Policy and Practice

    ERIC Educational Resources Information Center

    Schweig, Jonathan

    2014-01-01

    Measures of classroom and school environments are central to policy efforts that assess school and teacher quality. These measures are often formed by aggregating individual survey responses to form group-level measures, and assume an invariant measurement model holds across the individual and group levels. This article explores the tenability of…

  11. Idiopathic Polydactylous Longitudinal Erythronychia

    PubMed Central

    2011-01-01

    Objective: To describe the clinical features of idiopathic polydactylous longitudinal erythronychia. Introduction: Longitudinal erythronychia presents as a linear red band on the nail plate. Idiopathic polydactylous longitudinal erythronychia is a rarely described manifestation of longitudinal erythronychia in which one or more linear red bands present on the nails of multiple digits without any associated subungual malignant tumor, dermatological condition, or systemic disease. Methods: As part of a total body skin examination, the fingernails and toenails were evaluated for linear red bands. Results: One or more asymptomatic linear red bands (longitudinal erythronychia) was observed on multiple digits of the hands in one percent (3 men of 134 men and 112 women) of patients examined during a period of 75 days. The author also noted similar changes of his own nails. Between 3 to 10 digits were affected. Multiple linear red bands per nail were usually narrow (less than 1mm wide), whereas a single band on a nail often ranged from 4 to 6mm wide. The intensity of an individual wider linear red band was position-dependent in three individuals in whom the distal portion appeared less prominent when the affected digit was held upward above the level of the patient's heart—pseudolongitudinal erythronychia. Other nail changes in these patients included distal subungual hyperkeratosis, fissuring at the free end of the nail, leukonychia, red lunula, and splinter hemorrhages. Discussion: Idiopathic polydactylous longitudinal erythronychia is a benign, usually asymptomatic, condition of undetermined etiology characterized by one or more linear red bands originating at the proximal nail fold or distal lunula and extending to the free edge of the nail. It appears to be more prevalent in men over 50 years of age and its incidence was noted to be one percent of adults attending a dermatology clinic. Patients are either unaware of the nail changes or seek medical attention because

  12. Using Video to Examine Formative Assessment Practices as Measures of Expertise for Mathematics and Science Teachers

    ERIC Educational Resources Information Center

    Gotwals, Amelia Wenk; Philhower, Joanne; Cisterna, Dante; Bennett, Steven

    2015-01-01

    Formative assessment practices, including eliciting a broad range of student ideas, noticing the nuances in students' ideas, using these ideas to guide instruction, and promoting student self-regulation of learning are key components of expert teaching. Given the inherent dialogical nature of formative assessment in the classroom, video can…

  13. Measuring Science Instructional Practice: A Survey Tool for the Age of NGSS

    ERIC Educational Resources Information Center

    Hayes, Kathryn N.; Lee, Christine S.; DiStefano, Rachelle; O'Connor, Dawn; Seitz, Jeffery C.

    2016-01-01

    Ambitious efforts are taking place to implement a new vision for science education in the United States, in both Next Generation Science Standards (NGSS)-adopted states and those states creating their own, often related, standards. In-service and pre-service teacher educators are involved in supporting teacher shifts in practice toward the new…

  14. Conquering Mnemonophobia, with Help from Three Practical Measures of Memory and Application

    ERIC Educational Resources Information Center

    Carney, Russell N.; Levin, Joel R.

    2008-01-01

    Recent articles in "Teaching of Psychology" have endorsed the classroom use of various mnemonic techniques. Yet a degree of mnemonophobia (i.e., fear of using mnemonics) may persist in the minds of some "ToP" readers due to various lingering misconceptions. In this regard, we conducted 3 practical experiments with college students using the…

  15. Knowledge and Practice of Nursing Staff towards Infection Control Measures in the Palestinian Hospitals

    ERIC Educational Resources Information Center

    Fashafsheh, Imad; Ayed, Ahmad; Eqtait, Faeda; Harazneh, Lubna

    2015-01-01

    Health care professionals are constantly exposed to microorganisms. Many of which can cause serious or even lethal infections. Nurses in particular are often exposed to various infections during the course of carrying out their nursing activities. Therefore nurses should have sound knowledge and strict adherence to infection control practice. Aim…

  16. One Authentic Early Literacy Practice and Three Standardized Tests: Can a Storytelling Curriculum Measure up?

    ERIC Educational Resources Information Center

    Cooper, Patricia M.; Capo, Karen; Mathes, Bernie; Gray, Lincoln

    2007-01-01

    The current study was designed to assess the vocabulary and literacy skills of young children who participated in an authentic literacy practice, i.e., Vivian Paley's "storytelling curriculum," over the course of their respective prekindergarten or kindergarten years. We asked: How do prekindergarten and kindergarten age children, who participate…

  17. The H-PEPSS: an instrument to measure health professionals' perceptions of patient safety competence at entry into practice

    PubMed Central

    Castel, Evan; Tregunno, Deborah; Norton, Peter G

    2012-01-01

    Background Enhancing competency in patient safety at entry to practice requires introduction and integration of patient safety into health professional education. As efforts to include patient safety in health professional education increase, it is important to capture new health professionals' perspectives of their own patient safety competence at entry to practice. Existing instruments to measure patient safety knowledge, skills and attitudes have been developed largely to examine the impact of specific patient safety curricular initiatives and the psychometric analyses of the instruments used thus far have been exploratory in nature. Methods Confirmatory factor analytic approaches are used to extensively test the Health Professional Education in Patient Safety Survey (H-PEPSS), a newly designed survey rooted in a patient safety competency framework and designed to measure health professionals' self-reported patient safety competence around the time of entry to practice. The H-PEPSS focuses primarily on the socio-cultural aspects of patient safety including culture, teamwork, communication, managing risk and understanding human factors. Results Results support a parsimonious six-factor measurement model of health professionals' perceptions of patient safety competency. These results support the validity of a reduced version of the H-PEPSS and suggest it can be appropriately used at or near training completion with a variety of health professional groups. Conclusions Given increased demands for patient safety competency among health professionals at entry to practice and slow, but emerging changes in health professional education, ongoing research to understand the extent of patient safety competency among health professionals around the time of entry to practice will be important. PMID:22562876

  18. How Item Banks and Their Application Can Influence Measurement Practice in Rehabilitation Medicine: A PROMIS Fatigue Item Bank Example

    PubMed Central

    Lai, Jin-Shei; Cella, David; Choi, Seung; Junghaenel, Doerte U.; Christodoulou, Christopher; Gershon, Richard; Stone, Arthur

    2013-01-01

    Objective To illustrate how measurement practices can be advanced using as an example the fatigue item bank (FIB) and its applications (short-forms and computerized adaptive test) that were developed via the NIH Patient Reported Outcomes Measurement Information System (PROMIS) Cooperative Group. Design Psychometric analysis of data collected by an internet survey company using Item Response Theory (IRT) related techniques. Setting A United States general population representative sample collected via internet. Participants 803 respondents used for dimensionality evaluation of the PROMIS FIB and 14,931 respondents used for item calibrations Interventions Not applicable. Main Outcome Measures 112 fatigue items developed by the PROMIS fatigue domain working group, 13-item Functional Assessment of Chronic Illness Therapy-Fatigue, and 4-item SF-36 Vitality scale. Results The PROMIS FIB version 1 which consists of 95 items demonstrated acceptable psychometric properties. Computerized Adaptive Testing (CAT) showed consistently better precision than short-forms. However, all three short-forms showed good precision for the majority of participants, in that more than 95% of sample could be precisely measured with a reliability greater than 0.9. Conclusions Measurement practice can be advanced by using a psychometrically sound measurement tool and its applications. This example shows that CAT and short-forms derived from the PROMIS FIB can reliably estimate fatigue reported by the US general population. Evaluation in clinical populations is warranted before the item bank can be used for clinical trials. PMID:21958919

  19. [Dimensional structure of the Brazilian version of the s-EMBU instrument for measuring parental educational practices in adolescents].

    PubMed

    Reichenheim, Michael Eduardo; Sampaio, Paula Florence; Moraes, Claudia Leite

    2016-08-01

    The aim of this study was to assess the dimensional structure of the s-EMBU, used to measure parental educational practices in adolescents. The sample included 487 students from Greater Metropolitan Rio de Janeiro, Brazil, in 2013. Mean age was 14 years, and 47% were girls. The original dimensional structure was assessed by confirmatory factor analysis (CFA). The study also applied exploratory structural equation modeling (ESEM). CFA adjustment was unsatisfactory. In light of the ESEM, the most parsimonious solution concerned the three-factor model (RMSEA = 0.03, CFI = 0.97, and TLI = 0.96), but various items in the overprotection dimension showed higher factor loads in the rejection dimension. The items in the rejection and emotional warmth dimensions proved more appropriate. In Brazil, s-EMBU partially captures the proposed dimensions for measuring parental educational practices in adolescents. Emotional warmth had its dimensional structure confirmed, but rejection and especially overprotection require further refinement. PMID:27509553

  20. A Practical Solution to Optimizing the Reliability of Teaching Observation Measures under Budget Constraints

    ERIC Educational Resources Information Center

    Meyer, J. Patrick; Liu, Xiang; Mashburn, Andrew J.

    2014-01-01

    Researchers often use generalizability theory to estimate relative error variance and reliability in teaching observation measures. They also use it to plan future studies and design the best possible measurement procedures. However, designing the best possible measurement procedure comes at a cost, and researchers must stay within their budget…

  1. Measuring up: A Simple Lesson That Engages Students in Scientific Practices and Mathematics

    ERIC Educational Resources Information Center

    Capps, Daniel

    2012-01-01

    A well-known lesson taught by many upper-elementary and early-middle-school teachers at the beginning of the school year asks students to compare how arm span relates to height. Students measure their height and arm span and compare their measurements to those of their classmates. This lesson gets students measuring, graphing, and practicing…

  2. Longitudinal discharge laser baffles

    DOEpatents

    Warner, B.E.; Ault, E.R.

    1994-06-07

    The IR baffles placed between the window and the electrode of a longitudinal discharge laser improve laser performance by intercepting off-axis IR radiation from the laser and in doing so reduce window heating and subsequent optical distortion of the laser beam. 1 fig.

  3. Longitudinal discharge laser baffles

    DOEpatents

    Warner, Bruce E.; Ault, Earl R.

    1994-01-01

    The IR baffles placed between the window and the electrode of a longitudinal discharge laser improve laser performance by intercepting off-axis IR radiation from the laser and in doing so reduce window heating and subsequent optical distortion of the laser beam.

  4. Longitudinal discharge laser electrodes

    DOEpatents

    Warner, B.E.; Miller, J.L.; Ault, E.R.

    1994-08-23

    The improved longitudinal discharge laser electrode with IR baffle includes an electrode made up of washers spaced along the laser axis in order to form inter-washer spaces for hollow cathode discharge to take place and for IR radiation to be trapped. Additional IR baffles can be placed between the electrode ann the window. 2 figs.

  5. Longitudinal discharge laser electrodes

    DOEpatents

    Warner, Bruce E.; Miller, John L.; Ault, Earl R.

    1994-01-01

    The improved longitudinal discharge laser electrode with IR baffle includes an electrode made up of washers spaced along the laser axis in order to form inter-washer spaces for hollow cathode discharge to take place and for IR radiation to be trapped. Additional IR baffles can be placed between the electrode ann the window.

  6. WISCONSIN LONGITUDINAL STUDY (WLS)

    EPA Science Inventory

    The Wisconsin Longitudinal Study (WLS) is a long-term study of a random sample of 10,317 men and women who graduated from Wisconsin high schools in 1957. The WLS provides an opportunity to study of the life course, intergenerational transfers and relationships, family functioning...

  7. Research on high-accuracy two-dimensional digital image correlation hardware measurement systems used in the engineering practice

    NASA Astrophysics Data System (ADS)

    Chen, Guang; Ding, Keqin; Feng, Qibo

    2014-11-01

    Digital image correlation (DIC) method is a rapid development of photomechanics technology. The basic principle of the method is calculated the correlation between before and after deformation of the specimen surface speckle images, which is used to determine displacement and deformation. DIC measurement system includes hardware and software system. The former is the speckle image acquisition system, the latter are speckle image analysis algorithm and implementation procedures. Because the software analysis algorithm can achieve sub-pixel accuracy or even more, most of scholars have focused on the speckle image analysis algorithms. The system performance caused by the composition of hardware system has been less introduced. The hardware system mainly included the camera, lenses, lighting and other components. If hardware system is not perfect and stable, it will bring hundreds or even thousands of micro strain measurement error. These unfavorable factors make 2D-DIC inaccurate in small deformation tests. To some extent, it limits the application of 2D-DIC in the engineering practice. This paper analyzed that the various components of DIC hardware system impacted on the system performance, It was given that how to reasonably select the various components in the typical cases, as well as involved that the selection of 2D-DIC measurement system is applied to the actual engineering measurements in high temperature environment. These can provide support that 2D-DIC measurement system is better applied to the engineering practice.

  8. Using Longitudinal Assessment Data to Improve Retention and Student Experiences

    ERIC Educational Resources Information Center

    Trosset, Carol; Weisler, Steven

    2010-01-01

    The Wabash National Study of Liberal Arts Education presents a longitudinal analysis of how students change on a number of scales that purport to measure many of the outcomes of liberal learning over the span of a college education. The Wabash Study is designed to collect information longitudinally from students at the beginning and end of their…

  9. Measuring the quality of palliative care and supportive oncology: principles and practice.

    PubMed

    Dy, Sydney M

    2013-12-01

    Oncology quality measurement programs should include measures in key domains of palliative care and supportive oncology. This article describes an approach to quality measurement in these areas including the key steps of defining the quality measurement goal; identifying stakeholders and audiences; defining the population and setting (including potential characteristics of interest, such as specific conditions or disparities); and choosing the domain, target, and steps in the process of care, such as assessment and treatment. Other key steps include choosing or adapting measures that have been evaluated in other settings or are in widespread use; identifying data sources or collection needs; and considering issues of scientific acceptability, such as evidence to support process-outcome relationships. Other quality measurement considerations include the challenges of measurement, particularly in important domains such as communication and spiritual care, variation in patient preferences, or inconsistent documentation. In addition, potential unintended consequences, such as measurement burden and overemphasis of checklist care, may reduce patient-centeredness and attention to important patient concerns not addressed by quality measures. PMID:24645335

  10. Incorporating longitudinal pediatric patient-centered outcome measurement into the clinical workflow using a commercial electronic health record: a step toward increasing value for the patient.

    PubMed

    Carberry, Kathleen; Landman, Zachary; Xie, Michelle; Feeley, Thomas; Henderson, John; Fraser, Charles

    2016-01-01

    Patient-centered outcomes measurement provides healthcare organizations with crucial information for increasing value for patients; however, organizations have struggled to obtain outcomes data from electronic health record (EHR) systems. This study describes how Texas Children's Hospital customized a commercial EHR system and assembled a cross-functional team to capture outcomes data using existing functionality. Prior to its installation and customization, no surgical subspecialties besides the congenital heart and transplant surgery groups conducted prospective, patient outcomes measurement, but by 2015, the outcomes of over 1300 unique patients with supracondylar fractures, cleft lip and/or palate, or voiding dysfunction had been tracked. Key factors for integrating outcomes measurement into the clinical workflow include ongoing communication between cross-functional teams composed of clinicians and technical professionals, an iterative design process, organizational commitment, and prioritizing measurement as early as possible during EHR optimization. PMID:26377989

  11. Experimental Demonstration of Longitudinal Magnification

    ERIC Educational Resources Information Center

    Razpet, Nada; Susman, Katarina; Cepic, Mojca

    2009-01-01

    We describe an experiment which enables the observation of longitudinal magnification for the real image of a three-dimensional (3D) object formed by a converging lens. The experiment also shows the absence of longitudinal inversion. Possible reasons for misconceptions with respect to real images and longitudinal inversions are discussed and a…

  12. Including quality attributes in efficiency measures consistent with net benefit: creating incentives for evidence based medicine in practice.

    PubMed

    Eckermann, Simon; Coelli, Tim

    2013-01-01

    Evidence based medicine supports net benefit maximising therapies and strategies in processes of health technology assessment (HTA) for reimbursement and subsidy decisions internationally. However, translation of evidence based medicine to practice is impeded by efficiency measures such as cost per case-mix adjusted separation in hospitals, which ignore health effects of care. In this paper we identify a correspondence method that allows quality variables under control of providers to be incorporated in efficiency measures consistent with maximising net benefit. Including effects framed from a disutility bearing (utility reducing) perspective (e.g. mortality, morbidity or reduction in life years) as inputs and minimising quality inclusive costs on the cost-disutility plane is shown to enable efficiency measures consistent with maximising net benefit under a one to one correspondence. The method combines advantages of radial properties with an appropriate objective of maximising net benefit to overcome problems of inappropriate objectives implicit with alternative methods, whether specifying quality variables with utility bearing output (e.g. survival, reduction in morbidity or life years), hyperbolic or exogenous variables. This correspondence approach is illustrated in undertaking efficiency comparison at a clinical activity level for 45 Australian hospitals allowing for their costs and mortality rates per admission. Explicit coverage and comparability conditions of the underlying correspondence method are also shown to provide a robust framework for preventing cost-shifting and cream-skimming incentives, with appropriate qualification of analysis and support for data linkage and risk adjustment where these conditions are not satisfied. Comparison on the cost-disutility plane has previously been shown to have distinct advantages in comparing multiple strategies in HTA, which this paper naturally extends to a robust method and framework for comparing efficiency of

  13. Certifying Industrial Energy Efficiency Performance: AligningManagement, Measurement, and Practice to Create Market Value

    SciTech Connect

    McKane, Aimee; Scheihing, Paul; Williams, Robert

    2007-07-01

    More than fifteen years after the launch of programs in theU.K. and U.S., industry still offers one of the largest opportunities forenergy savings worldwide. The International Energy Agency (IEA) estimatesthe savings potential from cost-optimization of industrial motor-drivensystems alone at 7 percent of global electricity use. The U.S. Departmentof Energy (USDOE) Industrial Technologies Program estimates 7 percentsavings potential in total US industrial energy use through theapplication of proven best practice. Simple paybacks for these types ofprojects are frequently two years or less. The technology required toachieve these savings is widely available; the technical skills requiredto identify energy saving opportunities are known and transferable.Although programs like USDOE's Best Practices have been highlysuccessful, most plants, as supported by 2002 MECS data, remain eitherunaware or unmotivated to improve their energy efficiency--as evidencedby the 98 percent of US industrial facilities reporting to MECS say thatthey lack a full-time energy manager. With the renewed interest in energyefficiency worldwide and the emergence of carbon trading and newfinancial instruments such as white certificates1, there is a need tointroduce greater transparency into the way that industrial facilitiesidentify, develop, and document energy efficiency projects. Historically,industrial energy efficiency projects have been developed by plantengineers, frequently with assistance from consultants and/or supplierswith highly specialized technical skills. Under this scenario,implementation of energy efficiency improvements is dependent onindividuals. These individuals typically include "champions" within anindustrial facility or corporation, working in cooperation withconsultants or suppliers who have substantial knowledge based on years ofexperience. This approach is not easily understood by others without thisspecialized technical knowledge, penetrates the market fairly slowly

  14. An Early Intervention Project: A Longitudinal Look.

    ERIC Educational Resources Information Center

    Gordon, Ira J.

    This report describes the longitudinal research conducted in an early intervention program since 1966. The program is characterized by the use of paraprofessionals serving as home visitors and parent educators. Data collection has included measures of children's behavior and development, parent-child interactions, and parent variables such as…

  15. The Tevatron bunch by bunch longitudinal dampers

    SciTech Connect

    Cheng-Yang Tan and James Steimel

    2002-09-25

    We describe in this paper the Tevatron bunch by bunch dampers. The goal of the dampers is to stop the spontaneous longitudinal beam size blowup of the protons during a store. We will go through the theory and also show the measured results during the commissioning of this system. The system is currently operational and have stopped the beam blowups during a store.

  16. Elementary School Nurses' Perceptions and Practices regarding Body Mass Index Measurement in School Children

    ERIC Educational Resources Information Center

    Hendershot, Candace; Telljohann, Susan K.; Price, James H.; Dake, Joseph A.; Mosca, Nancy W.

    2008-01-01

    This study examines elementary school nurses' perceived efficacy expectations, perceived barriers, and perceived benefits to measuring body mass index (BMI) in students in schools with mandated BMI policies versus schools without mandated policies. Of the 2,629 school nurses participating in the study, 67% believe nurses should measure BMI in…

  17. Practical experience of using ultrasound flowmeters at the measurement associated petroleum gas

    NASA Astrophysics Data System (ADS)

    Fazlyyyakhmatov, M. G.; Kashapov, N. F.; Khayritonov, Kh A.; Lazarev, D. K.; Lazarev, V. K.

    2015-06-01

    The results of field tests of several ultrasound flowmeters at existing oil and gas extraction objects are given in the paper. Measured medium - associated petroleum gas. This work aims to create a unified system for measuring the amount and parameters of APG in order to reduce operating costs.

  18. Instruments for Measuring Nursing Practice and Other Health Care Variables: Volume I [and] Volume 2.

    ERIC Educational Resources Information Center

    Ward, Mary Jane, Ed.; Lindeman, Carol Ann, Ed.

    This two-volume compilation classifies, describes, and critiques 159 clinical nursing instruments; 140 which measure psychosocial variables, 19 which measure physiological variables. Instruments are in various formats: paper and pencil tests, questionnaires, interview schedules, observation guides, rating scales, and mechanical devices such as…

  19. RECOMMENDED PRACTICE FOR FLOW MEASUREMENT IN WASTEWATER TREATMENT PLANTS WITH VENTURI TUBES AND VENTURI NOZZLES

    EPA Science Inventory

    Venturi tubes and venturi nozzles are suitable for in-plant flow measurement of raw influent, treated effluent, return activated sludge, certain digested sludges, and for air and gas flows. However, they are not generally recommended for measurement of raw primary sludge. For cla...

  20. Are we making the grade? Practices and reported efficacy measures of primate conservation education programs.

    PubMed

    Kling, Katherine J; Hopkins, Mariah E

    2015-04-01

    Conservation education is often employed alongside primate conservation efforts with the aim of changing knowledge, attitudes, and behaviors toward non-human primates. Recommended best-use practices include longevity, use of program incentives, collaboration among educators, and adaptive program assessment, among others. This study surveys primate conservation education programs (PCEPs) to assess the frequency of suggested best-use practices, and to investigate impacts on program efficacy. Online surveys were collected from PCEPs in 2013-2014 (N = 43). The majority of programs reported lengths of 5-10 years, with participant involvement ranging widely from a day to several years. Non-economic and economic incentives were distributed by approximately half of all programs, with programs that provided economic incentives reporting positive participant attitude changes more frequently than those that did not (P = 0.03). While >70% of PCEPs consulted with community leaders, local teachers, and research scientists, only 45.9% collaborated with other conservation educators and only 27% collaborated with cultural experts such as cultural anthropologists. Programs that collaborated with other conservation educators were more likely to report reductions in threats to primates, specifically to bushmeat hunting and capture of primates for the pet trade (P = 0.07). Formal program evaluations were employed by 72.1% of all programs, with the majority of programs using surveys to assess changes to participant attitudes and knowledge. Formal evaluations of participant behavior, community attitudes and behaviors, and threats to primate populations were less common. While results indicate that PCEPs follow many suggested best-use practices, program impacts may be enhanced by greater discussion of economic incentivization, increased collaboration between conservation educators, and improved commitment to adaptive evaluation of changes to behaviors in addition to attitudes and