Hydrodynamic Force on a Cylinder Oscillating at Low Frequency

NASA Technical Reports Server (NTRS)

Berg, Robert F.; Yao, Minwu; Panzarella, Charles H.

2007-01-01

The hydrodynamic force on a cylinder oscillating transversely to its axis is a nonlinear function of the displacement amplitude x0. We report measurements and numerical calculations of the force at frequencies low enough that delta > R, where delta is the viscous penetration length and R is the cylinder radius. For small amplitudes, the numerically calculated Fourier transform of the force per unit length, F(sub small), agrees with Stokes' analytical calculation. For larger amplitudes, the force per unit length found by both calculation and measurement is F = F(sub small)C (x(sub 0)/delta,R/delta). The complex function C depends only weakly on R/delta, indicating that x0/delta is more appropriate as a scaling variable than the Keulegan-Carpenter number KC = pi*x(sub 0)/R. The measurements used a torsion oscillator driven at frequencies from 1 to 12 Hz while immersed in dense xenon. The oscillator comprised cylinders with an effective radius of R = 13.4 micron and oscillation amplitudes as large as x(sub 0)/delta = 4 (corresponding to KC as large as 71). The calculations used similar conditions except that the amplitudes were as large as x0/delta = 28.

Stabilizing low-frequency oscillation with two-stage filter in Hall thrusters

NASA Astrophysics Data System (ADS)

Wei, Liqiu; Han, Liang; Ding, Yongjie; Yu, Daren; Zhang, Chaohai

2017-07-01

The use of a filter is the most common method to suppress low-frequency discharge current oscillation in Hall thrusters. The only form of filter in actual use involves RLC networks, which serve the purpose of reducing the level of conducted electromagnetic interference returning to the power processing unit, which is the function of a filter. Recently, the role of the filter in the oscillation control was introduced. It has been noted that the filter regulates the voltage across itself according to the variation of discharge current so as to decrease its fluctuation in the discharge circuit, which is the function of a controller. Therefore, a kind of two-stage filter is proposed to fulfill these two purposes, filtering and controlling, and the detailed design methods are discussed and verified. A current oscillation attenuation ratio of 10 was achieved by different capacitance and inductance combinations of the filter stage, and the standard deviation of low-frequency oscillations decreased from 3 A-1 A by the control stage in our experiment.

Laser Raman spectroscopy of the effect of solvent on the low-frequency oscillations of organic molecules

NASA Astrophysics Data System (ADS)

Brandt, N. N.; Chikishev, A. Yu.; Dolgovskii, V. I.; Lebedenko, S. I.

2007-09-01

The effect of solvent on low-frequency oscillations is studied using an example of the 1,1,2,2-tetrachloroethane (TCE) and 1,1,2,2-tetrabromoethane (TBE) molecules, which exhibit torsional oscillations in the terahertz range. Dimethylsulfoxide (DMSO) and carbon tetrachloride (CTC) are used as solvents. It is demonstrated that a decrease in the concentration of the substance under study in the TBE/CTC, TCE/DMSO, and TCE/CTC mixtures leads to a frequency shift of the low-frequency oscillation. The shift is not observed in the TBE/DMSO mixture but a decrease in the TBE concentration causes significant broadening of the low-frequency line.

Synchronization of low-frequency oscillations in the cardiovascular system: Application to medical diagnostics and treatment

NASA Astrophysics Data System (ADS)

Ponomarenko, V. I.; Prokhorov, M. D.; Karavaev, A. S.; Kiselev, A. R.; Gridnev, V. I.; Bezruchko, B. P.

2013-10-01

We investigate synchronization between the low-frequency oscillations of heart rate and blood pressure having in humans a basic frequency close to 0.1 Hz. A quantitative estimation of this synchronization based on calculation of relative time of phase synchronization of oscillations is proposed. We show that assessment of synchronization between the considered oscillations can be useful for selecting an optimal dose of beta-blocker treatment in patients after acute myocardial infarction. It is found out that low value of synchronization between the low-frequency rhythms in heart rate and blood pressure at the first week after acute myocardial infarction is a sensitive marker of high risk of mortality during the subsequent 5 years.

Numerical study of low-frequency discharge oscillations in a 5 kW Hall thruster

NASA Astrophysics Data System (ADS)

Le, YANG; Tianping, ZHANG; Juanjuan, CHEN; Yanhui, JIA

2018-07-01

A two-dimensional particle-in-cell plasma model is built in the R–Z plane to investigate the low-frequency plasma oscillations in the discharge channel of a 5 kW LHT-140 Hall thruster. In addition to the elastic, excitation, and ionization collisions between neutral atoms and electrons, the Coulomb collisions between electrons and electrons and between electrons and ions are analyzed. The sheath characteristic distortion is also corrected. Simulation results indicate the capability of the built model to reproduce the low-frequency oscillation with high accuracy. The oscillations of the discharge current and ion density produced by the model are consistent with the existing conclusions. The model predicts a frequency that is consistent with that calculated by the zero-dimensional theoretical model.

Increased Amplitude of Thalamocortical Low-Frequency Oscillations in Patients with Migraine

PubMed Central

Wilcox, Sophie L.; Veggeberg, Rosanna; Noseda, Rodrigo; Burstein, Rami; Borsook, David; Becerra, Lino

2016-01-01

For many years, neurobiological theories have emphasized the importance of neuronal oscillations in the emergence of brain function. At the same time, clinical studies have shown that disturbances or irregularities in brain rhythms may relate to various common neurological conditions, including migraine. Increasing evidence suggests that the CNS plays a fundamental role in the predisposition to develop different forms of headache. Here, we present human imaging data that strongly support the presence of abnormal low-frequency oscillations (LFOs) in thalamocortical networks of patients in the interictal phase of migraine. Our results show that the main source of arrhythmic activity was localized to the higher-order thalamic relays of the medial dorsal nucleus. In addition, spontaneous LFOs in the thalamus were selectively associated with the headache attack frequency, meaning that the varying amplitude of dysrhythmia could predispose patients to recurrent attacks. Rhythmic cortical feedback to the thalamus is a major factor in the amplification of thalamocortical oscillations, making it a strong candidate for influencing neuronal excitability. We further speculate that the intrinsic dynamics of thalamocortical network oscillations are crucial for early sensory processing and therefore could underlie important pathophysiological processes involved in multisensory integration. SIGNIFICANCE STATEMENT In many cases, migraine attacks are thought to begin centrally. A major obstacle to studying intrinsic brain activity has been the identification of the precise anatomical structures and functional networks that are involved in migraine. Here, we present imaging data that strongly support the presence of abnormal low-frequency oscillations in thalamocortical networks of patients in the interictal phase of migraine. This arrhythmic activity was localized to the higher-order thalamic relays of the medial dorsal nucleus and was selectively associated with headache attack

Endogenous modulation of low frequency oscillations by temporal expectations

PubMed Central

Cravo, Andre M.; Rohenkohl, Gustavo; Wyart, Valentin

2011-01-01

Recent studies have associated increasing temporal expectations with synchronization of higher frequency oscillations and suppression of lower frequencies. In this experiment, we explore a proposal that low-frequency oscillations provide a mechanism for regulating temporal expectations. We used a speeded Go/No-go task and manipulated temporal expectations by changing the probability of target presentation after certain intervals. Across two conditions, the temporal conditional probability of target events differed substantially at the first of three possible intervals. We found that reactions times differed significantly at this first interval across conditions, decreasing with higher temporal expectations. Interestingly, the power of theta activity (4–8 Hz), distributed over central midline sites, also differed significantly across conditions at this first interval. Furthermore, we found a transient coupling between theta phase and beta power after the first interval in the condition with high temporal expectation for targets at this time point. Our results suggest that the adjustments in theta power and the phase-power coupling between theta and beta contribute to a central mechanism for controlling neural excitability according to temporal expectations. PMID:21900508

Gap Junction Modulation of Low-Frequency Oscillations in the Cerebellar Granule Cell Layer.

PubMed

Robinson, Jennifer Claire; Chapman, C Andrew; Courtemanche, Richard

2017-08-01

Local field potential (LFP) oscillations in the granule cell layer (GCL) of the cerebellar cortex have been identified previously in the awake rat and monkey during immobility. These low-frequency oscillations are thought to be generated through local circuit interactions between Golgi cells and granule cells within the GCL. Golgi cells display rhythmic firing and pacemaking properties, and also are electrically coupled through gap junctions within the GCL. Here, we tested if gap junctions in the rat cerebellar cortex contribute to the generation of LFP oscillations in the GCL. We recorded LFP oscillations under urethane anesthesia, and examined the effects of local infusion of gap junction blockers on 5-15 Hz oscillations. Local infusion of the gap junction blockers carbenoxolone and mefloquine resulted in significant decreases in the power of oscillations over a 30-min period, but the power of oscillations was unchanged in control experiments following vehicle injections. In addition, infusion of gap junction blockers had no significant effect on multi-unit activity, suggesting that the attenuation of low-frequency oscillations was likely due to reductions in electrical coupling rather than a decreased excitability within the granule cell layer. Our results indicate that electrical coupling among the Golgi cell networks in the cerebellar cortex contributes to the local circuit mechanisms that promote the occurrence of GCL LFP slow oscillations in the anesthetized rat.

High-frequency resonant-tunneling oscillators

NASA Technical Reports Server (NTRS)

Brown, E. R.; Parker, C. D.; Calawa, A. R.; Manfra, M. J.; Chen, C. L.

1991-01-01

Advances in high-frequency resonant-tunneling-diode (RTD) oscillators are described. Oscillations up to a frequency of 420 GHz have been achieved in the GaAs/AlAs system. Recent results obtained with In0.53Ga0.47As/AlAs and InAs/AlSb RTDs show a greatly increased power density and indicate the potential for fundamental oscillations up to about 1 THz. These results are consistent with a lumped-element equivalent circuit model of the RTD. The model shows that the maximum oscillation frequency of the GaAs/AlAs RTDs is limited primarily by series resistance, and that the power density is limited by low peak-to-valley current ratio.

Low-frequency oscillations in default mode subnetworks are associated with episodic memory impairments in Alzheimer's disease.

PubMed

Veldsman, Michele; Egorova, Natalia; Singh, Baljeet; Mungas, Dan; DeCarli, Charles; Brodtmann, Amy

2017-11-01

Disruptions to functional connectivity in subsystems of the default mode network are evident in Alzheimer's disease (AD). Functional connectivity estimates correlations in the time course of low-frequency activity. Much less is known about other potential perturbations to this activity, such as changes in the amplitude of oscillations and how this relates to cognition. We examined the amplitude of low-frequency fluctuations in 44 AD patients and 128 cognitively normal participants and related this to episodic memory, the core deficit in AD. We show higher amplitudes of low-frequency oscillations in AD patients. Rather than being compensatory, this appears to be maladaptive, with greater amplitude in the ventral default mode subnetwork associated with poorer episodic memory. Perturbations to default mode subnetworks in AD are evident in the amplitude of low-frequency oscillations in the resting brain. These disruptions are associated with episodic memory demonstrating their behavioral and clinical relevance in AD. Copyright © 2017 Elsevier Inc. All rights reserved.

VO2 film temperature dynamics at low-frequency current self-oscillations

NASA Astrophysics Data System (ADS)

Bortnikov, S. G.; Aliev, V. Sh.; Badmaeva, I. A.; Mzhelskiy, I. V.

2018-02-01

Low-frequency (˜2 Hz) current self-oscillations were first obtained in a millimeter-sized two-terminal planar device with a vanadium dioxide (VO2) film. The film temperature distribution dynamics was investigated within one oscillation period. It was established that the formation and disappearance of a conductive channel occur in a film in less than 60 ms with oscillation period 560 ms. The experimentally observed temperature in the channel region reached 413 K, being understated due to a low infrared microscope performance (integration time 10 ms). The VO2 film temperature distribution dynamics was simulated by solving a 2D problem of the electric current flow and heat transfer in the film. The calculation showed that the thermally initiated resistance switching in the film occurs in less than 4 ms at a channel temperature reaching ˜1000 K. The experimental results and simulation are consistent with the current self-oscillation mechanism based on the current pinching and dielectric relaxation in the VO2 film at the metal-insulator phase transition.

α-Adrenergic effects on low-frequency oscillations in blood pressure and R-R intervals during sympathetic activation.

PubMed

Kiviniemi, Antti M; Frances, Maria F; Tiinanen, Suvi; Craen, Rosemary; Rachinsky, Maxim; Petrella, Robert J; Seppänen, Tapio; Huikuri, Heikki V; Tulppo, Mikko P; Shoemaker, J Kevin

2011-08-01

The present study was designed to address the contribution of α-adrenergic modulation to the genesis of low-frequency (LF; 0.04-0.15 Hz) oscillations in R-R interval (RRi), blood pressure (BP) and muscle sympathetic nerve activity (MSNA) during different sympathetic stimuli. Blood pressure and RRi were measured continuously in 12 healthy subjects during 5 min periods each of lower body negative pressure (LBNP; -40 mmHg), static handgrip exercise (HG; 20% of maximal force) and postexercise forearm circulatory occlusion (PECO) with and without α-adrenergic blockade by phentolamine. Muscle sympathetic nerve activity was recorded in five subjects during LBNP and in six subjects during HG and PECO. Low-frequency powers and median frequencies of BP, RRi and MSNA were calculated from power spectra. Low-frequency power during LBNP was lower with phentolamine versus without for both BP and RRi oscillations (1.6 ± 0.6 versus 1.2 ± 0.7 ln mmHg(2), P = 0.049; and 6.9 ± 0.8 versus 5.4 ± 0.9 ln ms(2), P = 0.001, respectively). In contrast, the LBNP with phentolamine increased the power of high-frequency oscillations (0.15-0.4 Hz) in BP and MSNA (P < 0.01 for both), which was not observed during saline infusion. Phentolamine also blunted the increases in the LBNP-induced increase in frequency of LF oscillations in BP and RRi. Phentolamine decreased the LF power of RRi during HG (P = 0.015) but induced no other changes in LF powers or frequencies during HG. Phentolamine resulted in decreased frequency of LF oscillations in RRi (P = 0.004) during PECO, and a similar tendency was observed in BP and MSNA. The power of LF oscillation in MSNA did not change during any intervention. We conclude that α-adrenergic modulation contributes to LF oscillations in BP and RRi during baroreceptor unloading (LBNP) but not during static exercise. Also, α-adrenergic modulation partly explains the shift to a higher frequency of LF oscillations during baroreceptor unloading and muscle

The Influence of Low-frequency Oscillation Propagation of the Tibetan Plateau Vortex on Rainstorm Downstream

NASA Astrophysics Data System (ADS)

Xiao, Tiangui; Wang, Chao; La, Jia; Du, Jun; Zhang, Kairong

2017-04-01

Based on Tibetan Plateau vortex data, ERA-Interim and NCEP/NCAR reanalysis data, the characteristics of Tibetan Plateau vortex and the relationship with Low-Frequency Oscillation (LFO) from 2003 to 2012 were investigated. The heavy rainstorm occurred in Sichuan from June 29th to July 2nd in 2013, caused by the LFO, was studied. Besides, the signal of LFO, energy transmission and those influence to rainstorm were also investigate. The main conclusions are as follows: (1)Most of Tibetan Plateau vortex generate in eastern plateau, located at Tanggula Mountains, Zaduo, Dege, Qumalai and Qaidam. The moving-out Tibetan Plateau vortex mainly generate in Qumalai and most vortex occurrences during April to September. There are three directions of moving-out vortex paths: northeast, southeast and east. The areas which plateau vortex moving into are mainly distributed in Gansu, Sichuan, Shaanxi and Ningxia. (2)The zonal wind at 500hPa in plateau key region has a significant main 10-30d oscillation, with the secondly significant oscillation in 30-50d and the third in 70-90d. The relative vorticity at 500hPa in plateau key region has a significant main 30-50d oscillations, with the secondly significant oscillation in 10-30d. The 30-50d oscillation phase zone with weak westerly oscillation zone of 500hPa, and the 10-30d oscillation positive phase zone with weak oscillation zone of 500hPa are benefit to vortex generation. The 30-50d oscillation of zonal wind at 500hPa provides necessary circulation background for generation of plateau vortex, and positive phase region of 10-30d oscillation of relative vorticity at 500hPa provide necessary dynamic background conditions for it. (3) Comparing with the high frequency oscillation vortex, 10-25d low-frequency vortex is not significant at 500hPa before merging into the basin vortex. However, after merging into the basin vortex, there is a significant relationship between low-frequency vortex and the process of development, weakening and

Seismology and geodesy of the sun: Low-frequency oscillations.

PubMed

Dicke, R H

1981-04-01

The hourly averages of the solar ellipticity measured from June 13 to Sept. 17, 1966, are analyzed for indications of solar oscillations with periods in excess of 2 hr nu < 0.5 hr(-1). Nothing significant is found for frequencies nu > 0.1 hr(-1) but for lower frequencies the power spectrum shows a very complex structure containing about 20 strong narrow peaks. The complexity is illusionary. The signal apparently consists of only two frequencies. The complexity is due to aliasing by the window function with its basic 24-hr period, with many observational days missing, and with different numbers of hourly averages for the various observational days. Both signal frequencies are apparently due to odd-degree spherical harmonic oscillations of the sun.

Investigation of low-frequency-oscillating water flow in metal foam with 10 pores per inch

NASA Astrophysics Data System (ADS)

Bağcı, Ö.; Arbak, A.; De Paepe, M.; Dukhan, N.

2018-01-01

In this study, oscillating water flow in metal foam with open cells is investigated experimentally. The metal foam sample has a porosity of 88% and 10 pores. The water was oscillated in the test section with three frequencies between 0.116 Hz and 0.348 Hz, which are considered low for water oscillation, and three flow displacements ranging between 74.35 mm and 111.53 mm. The combinations of frequencies of displacements were studied for their impacts of dimensional and non-dimensional pressure loss quantities. To this purpose, friction factor was correlated as a function of kinetic Reynolds number. The same metal foam sample was studied by exposing it to steady-state water flow to investigate its permeability and drag coefficient in low-velocity flow regimes. The friction factor distribution for oscillating flow was found to be over that found for steady state. The outcomes of the study are important for studying heat transfer under the same flow conditions.

Optical parametric amplification and oscillation assisted by low-frequency stimulated emission.

PubMed

Longhi, Stefano

2016-04-15

Optical parametric amplification and oscillation provide powerful tools for coherent light generation in spectral regions inaccessible to lasers. Parametric gain is based on a frequency down-conversion process and, thus, it cannot be realized for signal waves at a frequency ω3 higher than the frequency of the pump wave ω1. In this Letter, we suggest a route toward the realization of upconversion optical parametric amplification and oscillation, i.e., amplification of the signal wave by a coherent pump wave of lower frequency, assisted by stimulated emission of the auxiliary idler wave. When the signal field is resonated in an optical cavity, parametric oscillation is obtained. Design parameters for the observation of upconversion optical parametric oscillation at λ3=465 nm are given for a periodically poled lithium-niobate (PPLN) crystal doped with Nd(3+) ions.

Seismology and geodesy of the sun: low-frequency oscillations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dicke, R.H.

1981-04-01

The hourly averages of the solar ellipticity measured from June 13 to September 17, 1966, are analyzed for indications of solar oscillations with periods in excess of 2 h ..nu.. < 0.5 h/sup -1/. Nothing significant is found for frequencies ..nu.. > 0.1 hr/sup -1/ but for lower frequencies the power spectrum shows a very complex structure containing about 20 strong narrow peaks. The complexity is illusionary. The signal apparently consists of only two frequencies. The complexity is due to aliasing by the window function with its basic 24-h period, with many observational days missing, and with different numbers ofmore » hourly averages for the various observational days. Both signal frequencies are apparently due to odd-degree spherical harmonic oscillations of the sun.« less

Low Frequency Plasma Oscillations in a 6-kW Magnetically Shielded Hall Thruster

NASA Technical Reports Server (NTRS)

Jorns, Benjamin A.; Hofery, Richard R.

2013-01-01

The oscillations from 0-100 kHz in a 6-kW magnetically shielded thruster are experimen- tally characterized. Changes in plasma parameters that result from the magnetic shielding of Hall thrusters have the potential to significantly alter thruster transients. A detailed investigation of the resulting oscillations is necessary both for the purpose of determin- ing the underlying physical processes governing time-dependent behavior in magnetically shielded thrusters as well as for improving thruster models. In this investigation, a high speed camera and a translating ion saturation probe are employed to examine the spatial extent and nature of oscillations from 0-100 kHz in the H6MS thruster. Two modes are identified at 8 kHz and 75-90 kHz. The low frequency mode is azimuthally uniform across the thruster face while the high frequency oscillation is concentrated close to the thruster centerline with an m = 1 azimuthal dependence. These experimental results are discussed in the context of wave theory as well as published observations from an unshielded variant of the H6MS thruster.

Enhanced detection of a low-frequency signal by using broad squeezed light and a bichromatic local oscillator

NASA Astrophysics Data System (ADS)

Li, Wei; Jin, Yuanbin; Yu, Xudong; Zhang, Jing

2017-08-01

We experimentally study a protocol of using the broadband high-frequency squeezed vacuum to detect the low-frequency signal. In this scheme, the lower sideband field of the squeezed light carries the low-frequency modulation signal, and the two strong coherent light fields are applied as the bichromatic local oscillator in the homodyne detection to measure the quantum entanglement of the upper and lower sideband for the broadband squeezed light. The power of one of the local oscillators for detecting the upper sideband can be adjusted to optimize the conditional variance in the low-frequency regime by subtracting the photocurrent of the upper sideband field of the squeezed light from that of the lower sideband field. By means of the quantum correlation of the upper and lower sideband for the broadband squeezed light, the low-frequency signal beyond the standard quantum limit is measured. This scheme is appropriate for enhancing the sensitivity of the low-frequency signal by the aid of the broad squeezed light, such as gravitational waves detection, and does not need to directly produce the low-frequency squeezing in an optical parametric process.

Synchronous Oscillations in Van Der Pol Generator with Modulated Natural Frequency

NASA Astrophysics Data System (ADS)

Nimets, A. Yu.; Vavriv, D. M.

2015-12-01

The synchronous operation of Van Der Pole generator with the low-frequency modulated natural frequency has been investigated. The presence of low-frequency modulation is shown to lead to formation of additional synchronization regions. The appearance of such regions is found to be caused by threefrequency resonances resulted from the interaction between oscillations of the generator natural frequency, modulation frequency and synchronized signal frequency. Characteristics of synchronous oscillations due to the below mentioned three-frequency interaction are obtained and comparison with the case of synchronization of oscillator on the main mode made.

Note: An approach to measurement of low frequency oscillation amplitude of discharge current of in-orbit Hall thruster.

PubMed

Han, Liang; Ding, Yongjie; Wei, Liqiu; Yu, Daren

2014-06-01

This paper provides a method to measure the amplitude of low frequency oscillation under the on-track working condition, and realizes the sampling by means of adding the circuit design of sampling, low pass filtering by 3 dB at 48.2 kHz, detection and integrating in the filtering unit. The experimental results prove that the measuring device of merely 0.8 g can quantitatively reflect the amplitude of low frequency oscillation in Hall thruster and the maximum deviation of experiment data and theory data is 10% FS.

The forgotten role of central volume in low frequency oscillations of heart rate variability.

PubMed

Ferrario, Manuela; Moissl, Ulrich; Garzotto, Francesco; Cruz, Dinna N; Tetta, Ciro; Signorini, Maria G; Ronco, Claudio; Grassmann, Aileen; Cerutti, Sergio; Guzzetti, Stefano

2015-01-01

The hypothesis that central volume plays a key role in the source of low frequency (LF) oscillations of heart rate variability (HRV) was tested in a population of end stage renal disease patients undergoing conventional hemodialysis (HD) treatment, and thus subject to large fluid shifts and sympathetic activation. Fluid overload (FO) in 58 chronic HD patients was assessed by whole body bioimpedance measurements before the midweek HD session. Heart Rate Variability (HRV) was measured using 24-hour Holter electrocardiogram recordings starting before the same HD treatment. Time domain and frequency domain analyses were performed on HRV signals. Patients were retrospectively classified in three groups according to tertiles of FO normalized to the extracellular water (FO/ECW%). These groups were also compared after stratification by diabetes mellitus. Patients with the low to medium hydration status before the treatment (i.e. 1st and 2nd FO/ECW% tertiles) showed a significant increase in LF power during last 30 min of HD compared to dialysis begin, while no significant change in LF power was seen in the third group (i.e. those with high pre-treatment hydration values). In conclusion, several mechanisms can generate LF oscillations in the cardiovascular system, including baroreflex feedback loops and central oscillators. However, the current results emphasize the role played by the central volume in determining the power of LF oscillations.

High frequency pressure oscillator for microcryocoolers.

PubMed

Vanapalli, S; ter Brake, H J M; Jansen, H V; Zhao, Y; Holland, H J; Burger, J F; Elwenspoek, M C

2008-04-01

Microminiature pulse tube cryocoolers should operate at a frequency of an order higher than the conventional macro ones because the pulse tube cryocooler operating frequency scales inversely with the square of the pulse tube diameter. In this paper, the design and experiments of a high frequency pressure oscillator is presented with the aim to power a micropulse tube cryocooler operating between 300 and 80 K, delivering a cooling power of 10 mW. Piezoelectric actuators operate efficiently at high frequencies and have high power density making them good candidates as drivers for high frequency pressure oscillator. The pressure oscillator described in this work consists of a membrane driven by a piezoelectric actuator. A pressure ratio of about 1.11 was achieved with a filling pressure of 2.5 MPa and compression volume of about 22.6 mm(3) when operating the actuator with a peak-to-peak sinusoidal voltage of 100 V at a frequency of 1 kHz. The electrical power input was 2.73 W. The high pressure ratio and low electrical input power at high frequencies would herald development of microminiature cryocoolers.

High frequency pressure oscillator for microcryocoolers

NASA Astrophysics Data System (ADS)

Vanapalli, S.; ter Brake, H. J. M.; Jansen, H. V.; Zhao, Y.; Holland, H. J.; Burger, J. F.; Elwenspoek, M. C.

2008-04-01

Microminiature pulse tube cryocoolers should operate at a frequency of an order higher than the conventional macro ones because the pulse tube cryocooler operating frequency scales inversely with the square of the pulse tube diameter. In this paper, the design and experiments of a high frequency pressure oscillator is presented with the aim to power a micropulse tube cryocooler operating between 300 and 80K, delivering a cooling power of 10mW. Piezoelectric actuators operate efficiently at high frequencies and have high power density making them good candidates as drivers for high frequency pressure oscillator. The pressure oscillator described in this work consists of a membrane driven by a piezoelectric actuator. A pressure ratio of about 1.11 was achieved with a filling pressure of 2.5MPa and compression volume of about 22.6mm3 when operating the actuator with a peak-to-peak sinusoidal voltage of 100V at a frequency of 1kHz. The electrical power input was 2.73W. The high pressure ratio and low electrical input power at high frequencies would herald development of microminiature cryocoolers.

Effective deep brain stimulation suppresses low-frequency network oscillations in the basal ganglia by regularizing neural firing patterns.

PubMed

McConnell, George C; So, Rosa Q; Hilliard, Justin D; Lopomo, Paola; Grill, Warren M

2012-11-07

Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective treatment for the motor symptoms of Parkinson's disease (PD). The effects of DBS depend strongly on stimulation frequency: high frequencies (>90 Hz) improve motor symptoms, while low frequencies (<50 Hz) are either ineffective or exacerbate symptoms. The neuronal basis for these frequency-dependent effects of DBS is unclear. The effects of different frequencies of STN-DBS on behavior and single-unit neuronal activity in the basal ganglia were studied in the unilateral 6-hydroxydopamine lesioned rat model of PD. Only high-frequency DBS reversed motor symptoms, and the effectiveness of DBS depended strongly on stimulation frequency in a manner reminiscent of its clinical effects in persons with PD. Quantification of single-unit activity in the globus pallidus externa (GPe) and substantia nigra reticulata (SNr) revealed that high-frequency DBS, but not low-frequency DBS, reduced pathological low-frequency oscillations (∼9 Hz) and entrained neurons to fire at the stimulation frequency. Similarly, the coherence between simultaneously recorded pairs of neurons within and across GPe and SNr shifted from the pathological low-frequency band to the stimulation frequency during high-frequency DBS, but not during low-frequency DBS. The changes in firing patterns in basal ganglia neurons were not correlated with changes in firing rate. These results indicate that high-frequency DBS is more effective than low-frequency DBS, not as a result of changes in firing rate, but rather due to its ability to replace pathological low-frequency network oscillations with a regularized pattern of neuronal firing.

Effective deep brain stimulation suppresses low frequency network oscillations in the basal ganglia by regularizing neural firing patterns

PubMed Central

McConnell, George C.; So, Rosa Q.; Hilliard, Justin D; Lopomo, Paola; Grill, Warren M.

2012-01-01

Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective treatment for the motor symptoms of Parkinson’s disease (PD). The effects of DBS depend strongly on stimulation frequency: high frequencies (>90Hz) improve motor symptoms, while low frequencies (<50Hz) are either ineffective or exacerbate symptoms. The neuronal basis for these frequency-dependent effects of DBS is unclear. The effects of different frequencies of STN-DBS on behavior and single-unit neuronal activity in the basal ganglia were studied in the unilateral 6-hydroxydopamine lesioned rat model of PD. Only high frequency DBS reversed motor symptoms and the effectiveness of DBS depended strongly on stimulation frequency in a manner reminiscent of its clinical effects in persons with PD. Quantification of single-unit activity in the globus pallidus externa (GPe) and substantia nigra reticulata (SNr) revealed that high frequency DBS, but not low frequency DBS, reduced pathological low frequency oscillations (~9Hz) and entrained neurons to fire at the stimulation frequency. Similarly, the coherence between simultaneously recorded pairs of neurons within and across GPe and SNr shifted from the pathological low frequency band to the stimulation frequency during high frequency DBS, but not during low frequency DBS. The changes in firing patterns in basal ganglia neurons were not correlated with changes in firing rate. These results indicate that high frequency DBS is more effective than low frequency DBS, not as a result of changes in firing rate, but rather due to its ability to replace pathological low frequency network oscillations with a regularized pattern of neuronal firing. PMID:23136407

Frontal top-down signals increase coupling of auditory low-frequency oscillations to continuous speech in human listeners.

PubMed

Park, Hyojin; Ince, Robin A A; Schyns, Philippe G; Thut, Gregor; Gross, Joachim

2015-06-15

Humans show a remarkable ability to understand continuous speech even under adverse listening conditions. This ability critically relies on dynamically updated predictions of incoming sensory information, but exactly how top-down predictions improve speech processing is still unclear. Brain oscillations are a likely mechanism for these top-down predictions [1, 2]. Quasi-rhythmic components in speech are known to entrain low-frequency oscillations in auditory areas [3, 4], and this entrainment increases with intelligibility [5]. We hypothesize that top-down signals from frontal brain areas causally modulate the phase of brain oscillations in auditory cortex. We use magnetoencephalography (MEG) to monitor brain oscillations in 22 participants during continuous speech perception. We characterize prominent spectral components of speech-brain coupling in auditory cortex and use causal connectivity analysis (transfer entropy) to identify the top-down signals driving this coupling more strongly during intelligible speech than during unintelligible speech. We report three main findings. First, frontal and motor cortices significantly modulate the phase of speech-coupled low-frequency oscillations in auditory cortex, and this effect depends on intelligibility of speech. Second, top-down signals are significantly stronger for left auditory cortex than for right auditory cortex. Third, speech-auditory cortex coupling is enhanced as a function of stronger top-down signals. Together, our results suggest that low-frequency brain oscillations play a role in implementing predictive top-down control during continuous speech perception and that top-down control is largely directed at left auditory cortex. This suggests a close relationship between (left-lateralized) speech production areas and the implementation of top-down control in continuous speech perception. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

Frontal Top-Down Signals Increase Coupling of Auditory Low-Frequency Oscillations to Continuous Speech in Human Listeners

PubMed Central

Park, Hyojin; Ince, Robin A.A.; Schyns, Philippe G.; Thut, Gregor; Gross, Joachim

2015-01-01

Summary Humans show a remarkable ability to understand continuous speech even under adverse listening conditions. This ability critically relies on dynamically updated predictions of incoming sensory information, but exactly how top-down predictions improve speech processing is still unclear. Brain oscillations are a likely mechanism for these top-down predictions [1, 2]. Quasi-rhythmic components in speech are known to entrain low-frequency oscillations in auditory areas [3, 4], and this entrainment increases with intelligibility [5]. We hypothesize that top-down signals from frontal brain areas causally modulate the phase of brain oscillations in auditory cortex. We use magnetoencephalography (MEG) to monitor brain oscillations in 22 participants during continuous speech perception. We characterize prominent spectral components of speech-brain coupling in auditory cortex and use causal connectivity analysis (transfer entropy) to identify the top-down signals driving this coupling more strongly during intelligible speech than during unintelligible speech. We report three main findings. First, frontal and motor cortices significantly modulate the phase of speech-coupled low-frequency oscillations in auditory cortex, and this effect depends on intelligibility of speech. Second, top-down signals are significantly stronger for left auditory cortex than for right auditory cortex. Third, speech-auditory cortex coupling is enhanced as a function of stronger top-down signals. Together, our results suggest that low-frequency brain oscillations play a role in implementing predictive top-down control during continuous speech perception and that top-down control is largely directed at left auditory cortex. This suggests a close relationship between (left-lateralized) speech production areas and the implementation of top-down control in continuous speech perception. PMID:26028433

Persistent lung oscillator response to CO2 after buccal oscillator inhibition in the adult frog.

PubMed

Leclère, Renaud; Straus, Christian; Similowski, Thomas; Bodineau, Laurence; Fiamma, Marie-Noëlle

2012-08-15

The automatic ventilatory drive in amphibians depends on two oscillators interacting with each other, the gill/buccal and lung oscillators. The lung oscillator would be homologous to the mammalian pre-Bötzinger complex and the gill/buccal oscillator homologous to the mammalian parafacial respiratory group/retrotrapezoid nucleus (pFRG/RTN). Dysfunction of the pFRG/RTN has been involved in the development of respiratory diseases associated to the loss of CO(2) chemosensitivity such as the congenital central hypoventilation syndrome. Here, on adult in vitro isolated frog brainstem, consequences of the buccal oscillator inhibition (by reducing Cl(-)) were evaluated on the respiratory rhythm developed by the lung oscillator under hypercapnic challenges. Our results show that under low Cl(-) concentration (i) the buccal oscillator is strongly inhibited and the lung burst frequency and amplitude decreased and (ii) it persists a powerful CO(2) chemosensitivity. In conclusion, in frog, the CO(2) chemosensitivity depends on cellular contingent(s) whose the functioning is independent of the concentration of Cl(-) and origin remains unknown. Copyright © 2012 Elsevier B.V. All rights reserved.

Whole blood of mammalian species in the oscillating shear field: influence of erythrocyte aggregation

NASA Astrophysics Data System (ADS)

Windberger, U.; Pöschl, Ch; Peters, S.; Huber, J.; van den Hoven, R.

2017-02-01

This is the rheologicalanalysis of mammalian blood of species with a high (horse), medium (man), and low (sheep) erythrocyte (RBC) aggregability by small amplitude oscillation technique. Amplitude and frequency sweep tests in linear mode were performed with blood from healthy adult volunteers, horses, and sheep in CSS-mode. Blood samples were hematocrit (HCT) adjusted (40%, 50%, 60%) and tested at 7°C, 22°C, and 37°C. Storage modulus (G‧) increased with HCT and decreased with temperature in each species, but the gradient of this increase was species-specific. The lower dependency of G‧ on the equine HCT value could be a benefit during physical performance when high numbers of RBCs are released from the spleen in the horse. In sheep, a HCT-threshold had to be overcome before elasticity of the blood sample could be measured, suggesting that the cohesive forces between RBCs, and between RBCs and plasma molecules must be very low. The frequencies for tests under quasi-staticcondition were in a narrow range around the physiologic heart rate of the species. In horse, time-dependent influences concurred at frequencies lower than 3 rad.s-1 probably due to sedimentation of RBC aggregates. In conclusion, elasticity of blood depends not only on the amount of blood cells, but also on their mechanical and functional properties.

A dual resonant rectilinear-to-rotary oscillation converter for low frequency broadband electromagnetic energy harvesting

NASA Astrophysics Data System (ADS)

Deng, Wei; Wang, Ya

2017-09-01

This paper reports a dual resonant rectilinear-to-rotary oscillation converter (RROC) for low frequency broadband electromagnetic energy harvesting from ambient vibrations. An approximate theoretical model has been established to integrate the electromechanical coupling into a comprehensive electromagnetic-dynamic model of the dual resonant RROC. Numerical simulation has proved the nature of dual resonances by revealing that both the rectilinear resonance and the rotary resonance could be achieved when the stand-alone rectilinear oscillator (RLO) and the stand-alone rotary oscillator (RTO) were excited independently. Simulation on the magnetically coupled RROC has also shown that the rectilinear resonance and the rotary resonance could be obtained simultaneously in the low-frequency region (2-14 Hz) with well-defined restoring torque (M r ) and the initial rotation angle of the RLO (ψ). The magnetic interaction patterns between the rectilinear and the RTOs have been categorized based on aforementioned simulation results. Both simulation and experimental results have demonstrated broadband output attributing from the dual resonances. Experimental results have also indicated that the RROC could have wide bandwidth in a much lower frequency region (2-8 Hz) even without the rotary resonance as long as the system parameters are carefully tuned. Parameter analysis on different values of M r and ψ are experimentally carried out to provide a quantitative guidance of designing the RROC to achieve an optimal power density.

High-frequency sarcomeric auto-oscillations induced by heating in living neonatal cardiomyocytes of the rat

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shintani, Seine A.; Oyama, Kotaro; Fukuda, Norio, E-mail: noriof@jikei.ac.jp

2015-02-06

Highlights: • We tested the effects of infra-red laser irradiation on cardiac sarcomere dynamics. • A rise in temperature (>∼38 °C) induced high-frequency sarcomeric auto-oscillations. • These oscillations occurred with and without blockade of intracellular Ca{sup 2+} stores. • Cardiac sarcomeres can play a role as a temperature-dependent rhythm generator. - Abstract: In the present study, we investigated the effects of infra-red laser irradiation on sarcomere dynamics in living neonatal cardiomyocytes of the rat. A rapid increase in temperature to >∼38 °C induced [Ca{sup 2+}]{sub i}-independent high-frequency (∼5–10 Hz) sarcomeric auto-oscillations (Hyperthermal Sarcomeric Oscillations; HSOs). In myocytes with the intactmore » sarcoplasmic reticular functions, HSOs coexisted with [Ca{sup 2+}]{sub i}-dependent spontaneous beating in the same sarcomeres, with markedly varying frequencies (∼10 and ∼1 Hz for the former and latter, respectively). HSOs likewise occurred following blockade of the sarcoplasmic reticular functions, with the amplitude becoming larger and the frequency lower in a time-dependent manner. The present findings suggest that in the mammalian heart, sarcomeres spontaneously oscillate at higher frequencies than the sinus rhythm at temperatures slightly above the physiologically relevant levels.« less

Experiments and characterization of low-frequency oscillations in a granular column

NASA Astrophysics Data System (ADS)

Oyarte Gálvez, Loreto; Rivas, Nicolás; van der Meer, Devaraj

2018-04-01

The behavior of a vertically vibrated granular bed is reminiscent of a liquid in that it exhibits many phenomena such as convection and Faraday-like surface waves. However, when the lateral dimensions of the bed are confined such that a quasi-one-dimensional geometry is formed, the only phenomena that remain are bouncing bed and the granular Leidenfrost effect. This permits the observation of the granular Leidenfrost state for a wide range of energy injection parameters and more specifically allows for a thorough characterization of the low-frequency oscillation (LFO) that is present in this state. In both experiments and particle simulations we determine the LFO frequency from the power spectral density of the center-of-mass signal of the grains, varying the amplitude and frequency of the driving, the particle diameter, and the number of layers in the system. We thus find that the LFO frequency (i) is inversely proportional to the fast inertial timescale and (ii) decorrelates with a typical decay time proportional to the slow dissipative timescale in the system. The latter is consistent with the view that the LFO is driven by the inherent noise that is present in the granular Leidenfrost state with a low number of particles.

Low-Frequency Cortical Oscillations Entrain to Subthreshold Rhythmic Auditory Stimuli

PubMed Central

Schroeder, Charles E.; Poeppel, David; van Atteveldt, Nienke

2017-01-01

Many environmental stimuli contain temporal regularities, a feature that can help predict forthcoming input. Phase locking (entrainment) of ongoing low-frequency neuronal oscillations to rhythmic stimuli is proposed as a potential mechanism for enhancing neuronal responses and perceptual sensitivity, by aligning high-excitability phases to events within a stimulus stream. Previous experiments show that rhythmic structure has a behavioral benefit even when the rhythm itself is below perceptual detection thresholds (ten Oever et al., 2014). It is not known whether this “inaudible” rhythmic sound stream also induces entrainment. Here we tested this hypothesis using magnetoencephalography and electrocorticography in humans to record changes in neuronal activity as subthreshold rhythmic stimuli gradually became audible. We found that significant phase locking to the rhythmic sounds preceded participants' detection of them. Moreover, no significant auditory-evoked responses accompanied this prethreshold entrainment. These auditory-evoked responses, distinguished by robust, broad-band increases in intertrial coherence, only appeared after sounds were reported as audible. Taken together with the reduced perceptual thresholds observed for rhythmic sequences, these findings support the proposition that entrainment of low-frequency oscillations serves a mechanistic role in enhancing perceptual sensitivity for temporally predictive sounds. This framework has broad implications for understanding the neural mechanisms involved in generating temporal predictions and their relevance for perception, attention, and awareness. SIGNIFICANCE STATEMENT The environment is full of rhythmically structured signals that the nervous system can exploit for information processing. Thus, it is important to understand how the brain processes such temporally structured, regular features of external stimuli. Here we report the alignment of slowly fluctuating oscillatory brain activity to

Low Frequency Quasi-periodic Oscillations in the High-eccentric LMXB Cir X-1: Extending the WK Correlation for Z Sources

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bu, Qingcui; Chen, Li; Belloni, T. M.

Using archival Rossi X-ray Timing Explorer ( RXTE ) data, we studied the low-frequency quasi-periodic oscillations (LFQPOs) in the neutron star low-mass X-ray binary (LMXB) Cir X-1 and examined their contribution to frequency–frequency correlations for Z sources. We also studied the orbital phase effects on the LFQPO properties and found them to be phase independent. Comparing LFQPO frequencies in different classes of LMXBs, we found that systems that show both Z and atoll states form a common track with atoll/BH sources in the so-called WK correlation, while persistent Z systems are offset by a factor of about two. We foundmore » that neither source luminosity nor mass accretion rate is related to the shift of persistent Z systems. We discuss the possibility of a misidentification of fundamental frequency for horizontal branch oscillations from persistent Z systems and interpreted the oscillations in terms of models based on relativistic precession.« less

The hallucinogen DOI reduces low-frequency oscillations in rat prefrontal cortex: reversal by antipsychotic drugs.

PubMed

Celada, Pau; Puig, M Victoria; Díaz-Mataix, Llorenç; Artigas, Francesc

2008-09-01

Perceptual and psychic alterations and thought disorder are fundamental elements of schizophrenia symptoms, a pathology associated with an abnormal macro- and microcircuitry of several brain areas including the prefrontal cortex (PFC). Alterations in information processing in PFC may partly underlie schizophrenia symptoms. The 5-HT(2A/2C) agonist DOI and antipsychotic drugs were administered to anesthetized rats. Single unit and local field potential (LFP) extracellular recordings were made in medial PFC (mPFC). Electrolytic lesions were performed in the thalamic nuclei. DOI markedly disrupts cellular and network activity in rat PFC. DOI altered pyramidal discharge in mPFC (39% excited, 27% inhibited, 34% unaffected; n = 51). In all instances, DOI concurrently reduced low-frequency oscillations (.3-4 Hz; power spectrum: .25 +/- .02 and .14 +/- .01 microV(2) in basal conditions and after 50-300 microg/kg intravenous (i.v.) DOI, respectively; n = 51). Moreover, DOI disrupted the temporal association between the active phase of LFP and pyramidal discharge. Both effects were reversed by M100907 (5-HT(2A) receptor antagonist) and were not attenuated by thalamic lesions, supporting an intracortical origin of the effects of DOI. The reduction in low-frequency oscillations induced by DOI was significantly reversed by the antipsychotic drugs haloperidol (.1-.2 mg/kg i.v.) and clozapine (1 mg/kg i.v.). DOI disorganizes network activity in PFC, reducing low-frequency oscillations and desynchronizing pyramidal discharge from active phases of LFP. These effects may underlie DOI's psychotomimetic action. The reversal by clozapine and haloperidol indicates that antipsychotic drugs may reduce psychotic symptoms by normalizing an altered PFC function.

Resonance condition and low-frequency quasi-periodic oscillations of the outbursting source H1743-322

NASA Astrophysics Data System (ADS)

Chakrabarti, Sandip K.; Mondal, Santanu; Debnath, Dipak

2015-10-01

It has long been proposed that low-frequency quasi-periodic oscillations (QPOs) in stellar-mass black holes or their equivalents in supermassive black holes are the result of resonances between infall and cooling timescales. We explicitly compute these two timescales in a generic situation to show that resonances are easily achieved. During an outburst of a transient black hole candidate, the accretion rate of the Keplerian disc as well as the geometry of the Comptonizing cloud change very rapidly. During some period, a resonance condition between the cooling timescale (predominantly by Comptonization) and the infall timescale of the Comptonizing cloud is roughly satisfied. This leads to low-frequency quasi-periodic oscillations (LFQPOs) of the Compton cloud and the consequent oscillation of hard X-rays. In this paper, we explicitly follow black hole candidate H1743-322 during its 2010 outburst. We compute the Compton cooling time and infall time over several days and show that QPOs take place when these two roughly agree within ˜50 per cent, i.e., the resonance condition is generally satisfied. We also confirm that for the sharper LFQPOs (i.e. higher Q-factors) the ratio of the two timescales is very close to 1.

In vivo imaging of spontaneous low-frequency oscillations in cerebral hemodynamics with a digital red-green-blue camera

NASA Astrophysics Data System (ADS)

Mustari, Afrina; Nakamura, Naoki; Nishidate, Izumi; Kawauchi, Satoko; Sato, Shunichi; Sato, Manabu; Kokobo, Yasuaki

2017-04-01

Nervous system relies on a continuous and adequate supply of blood flow, bringing the nutrients that it needs and removing the waste products of metabolism. Failure of these mechanisms is found in a number of devastating cerebral diseases, including stroke, vascular dementia, brain injury and trauma. Vasomotion which is the spontaneous low-frequency oscillation derived by the contraction and relaxation of arterioles and appears to be an intrinsic property of the cerebral vasculature, is important for monitoring the cerebral flow, tissue metabolism and health status of brain tissue. In the present study, we investigated a method to visualize the spontaneous low-frequency oscillation of cerebral blood volume based on the sequential RGB images of exposed brain.

Frequency-locked chaotic opto-RF oscillator.

PubMed

Thorette, Aurélien; Romanelli, Marco; Brunel, Marc; Vallet, Marc

2016-06-15

A driven opto-RF oscillator, consisting of a dual-frequency laser (DFL) submitted to frequency-shifted feedback, is experimentally and numerically studied in a chaotic regime. Precise control of the reinjection strength and detuning permits isolation of a parameter region of bounded-phase chaos, where the opto-RF oscillator is frequency-locked to the master oscillator, in spite of chaotic phase and intensity oscillations. Robust experimental evidence of this synchronization regime is found, and phase noise spectra allow us to compare phase-locking and bounded-phase chaos regimes. In particular, it is found that the long-term phase stability of the master oscillator is well transferred to the opto-RF oscillator, even in the chaotic regime.

Characterization of Low-Frequency Combustion Stability of the Fastrac Engine

NASA Technical Reports Server (NTRS)

Rocker, Marvin; Jones, Preston (Technical Monitor)

2002-01-01

A series of tests were conducted to measure the combustion performance of the Fastrac engine thrust chamber. During mainstage, the thrust chamber exhibited no large-amplitude chamber pressure oscillations that could be identified as low-frequency combustion instability or 'chug'. However, during start-up and shutdown, the thrust chamber very briefly exhibited large-amplitude chamber pressure oscillations that were identified as chug. These instabilities during start-up and shutdown were regarded as benign due to their brevity. Linear models of the thrust chamber and the propellant feed systems were formulated for both the thrust chamber component tests and the flight engine tests. These linear models determined the frequency and decay rate of chamber pressure oscillations given the design and operating conditions of the thrust chamber and feed system. The frequency of chamber pressure oscillations determined from the model closely matched the frequency of low-amplitude, low-frequency chamber pressure oscillations exhibited in some of the later thrust chamber mainstage tests. The decay rate of the chamber pressure oscillations determined from the models indicated that these low-frequency oscillations were stable. Likewise, the decay rate, determined from the model of the flight engine tests indicated that the low-frequency chamber pressure oscillations would be stable.

Ictal high frequency oscillations distinguish two types of seizure territories in humans

PubMed Central

Weiss, Shennan A.; Banks, Garrett P.; McKhann, Guy M.; Goodman, Robert R.; Emerson, Ronald G.; Trevelyan, Andrew J.

2013-01-01

High frequency oscillations have been proposed as a clinically useful biomarker of seizure generating sites. We used a unique set of human microelectrode array recordings (four patients, 10 seizures), in which propagating seizure wavefronts could be readily identified, to investigate the basis of ictal high frequency activity at the cortical (subdural) surface. Sustained, repetitive transient increases in high gamma (80–150 Hz) amplitude, phase-locked to the low-frequency (1–25 Hz) ictal rhythm, correlated with strong multi-unit firing bursts synchronized across the core territory of the seizure. These repetitive high frequency oscillations were seen in recordings from subdural electrodes adjacent to the microelectrode array several seconds after seizure onset, following ictal wavefront passage. Conversely, microelectrode recordings demonstrating only low-level, heterogeneous neural firing correlated with a lack of high frequency oscillations in adjacent subdural recording sites, despite the presence of a strong low-frequency signature. Previously, we reported that this pattern indicates a failure of the seizure to invade the area, because of a feedforward inhibitory veto mechanism. Because multi-unit firing rate and high gamma amplitude are closely related, high frequency oscillations can be used as a surrogate marker to distinguish the core seizure territory from the surrounding penumbra. We developed an efficient measure to detect delayed-onset, sustained ictal high frequency oscillations based on cross-frequency coupling between high gamma amplitude and the low-frequency (1–25 Hz) ictal rhythm. When applied to the broader subdural recording, this measure consistently predicted the timing or failure of ictal invasion, and revealed a surprisingly small and slowly spreading seizure core surrounded by a far larger penumbral territory. Our findings thus establish an underlying neural mechanism for delayed-onset, sustained ictal high frequency oscillations, and

A Low Power Low Phase Noise Oscillator for MICS Transceivers

PubMed Central

Li, Dawei; Liu, Dongsheng; Kang, Chaojian; Zou, Xuecheng

2017-01-01

A low-power, low-phase-noise quadrature oscillator for Medical Implantable Communications Service (MICS) transceivers is presented. The proposed quadrature oscillator generates 349~689 MHz I/Q (In-phase and Quadrature) signals covering the MICS band. The oscillator is based on a differential pair with positive feedback. Each delay cell consists of a few transistors enabling lower voltage operation. Since the oscillator is very sensitive to disturbances in the supply voltage and ground, a self-bias circuit for isolating the voltage disturbance is proposed to achieve bias voltages which can track the disturbances from the supply and ground. The oscillation frequency, which is controlled by the bias voltages, is less sensitive to the supply and ground noise, and a low phase noise is achieved. The chip is fabricated in the UMC (United Microelectronics Corporation) 0.18 μm CMOS (Complementary Metal Oxide Semiconductor) process; the core just occupies a 28.5 × 22 μm2 area. The measured phase noise is −108.45 dBc/Hz at a 1 MHz offset with a center frequency of 540 MHz. The gain of the oscillator is 0.309 MHz/mV with a control voltage from 0 V to 1.1 V. The circuit can work with a supply voltage as low as 1.2 V and the power consumption is only 0.46 mW at a 1.8 V supply voltage. PMID:28085107

A Low Power Low Phase Noise Oscillator for MICS Transceivers.

PubMed

Li, Dawei; Liu, Dongsheng; Kang, Chaojian; Zou, Xuecheng

2017-01-12

A low-power, low-phase-noise quadrature oscillator for Medical Implantable Communications Service (MICS) transceivers is presented. The proposed quadrature oscillator generates 349~689 MHz I/Q (In-phase and Quadrature) signals covering the MICS band. The oscillator is based on a differential pair with positive feedback. Each delay cell consists of a few transistors enabling lower voltage operation. Since the oscillator is very sensitive to disturbances in the supply voltage and ground, a self-bias circuit for isolating the voltage disturbance is proposed to achieve bias voltages which can track the disturbances from the supply and ground. The oscillation frequency, which is controlled by the bias voltages, is less sensitive to the supply and ground noise, and a low phase noise is achieved. The chip is fabricated in the UMC (United Microelectronics Corporation) 0.18 μm CMOS (Complementary Metal Oxide Semiconductor) process; the core just occupies a 28.5 × 22 μm² area. The measured phase noise is -108.45 dBc/Hz at a 1 MHz offset with a center frequency of 540 MHz. The gain of the oscillator is 0.309 MHz/mV with a control voltage from 0 V to 1.1 V. The circuit can work with a supply voltage as low as 1.2 V and the power consumption is only 0.46 mW at a 1.8 V supply voltage.

Frequency and amplitude stabilization in MEMS and NEMS oscillators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, Changyao; Lopez, Omar Daniel; Czaplewski, David A.

This invention comprises a nonlinear micro- and nano-mechanical resonator that can maintain frequency of operation and amplitude of operation for a period of time after all external power has been removed from the device. Utilizing specific nonlinear dynamics of the micromechanical resonator, mechanical energy at low frequencies can be input and stored in higher frequencies modes, thus using the multiple degrees of freedom of the resonator to extend its energy storage capacity. Furthermore, the energy stored in multiple vibrational modes can be used to maintain the resonator oscillating for a fixed period of time, even without an external power supply.more » This is the first demonstration of an "autonomous" frequency source that can maintain a constant frequency and vibrating amplitude when no external power is provided, making it ideal for applications requiring an oscillator in low power, or limited and intermittent power supplies.« less

From quiescence to proliferation: Cdk oscillations drive the mammalian cell cycle

PubMed Central

Gérard, Claude; Goldbeter, Albert

2012-01-01

We recently proposed a detailed model describing the dynamics of the network of cyclin-dependent kinases (Cdks) driving the mammalian cell cycle (Gérard and Goldbeter, 2009). The model contains four modules, each centered around one cyclin/Cdk complex. Cyclin D/Cdk4–6 and cyclin E/Cdk2 promote progression in G1 and elicit the G1/S transition, respectively; cyclin A/Cdk2 ensures progression in S and the transition S/G2, while the activity of cyclin B/Cdk1 brings about the G2/M transition. This model shows that in the presence of sufficient amounts of growth factor the Cdk network is capable of temporal self-organization in the form of sustained oscillations, which correspond to the ordered, sequential activation of the various cyclin/Cdk complexes that control the successive phases of the cell cycle. The results suggest that the switch from cellular quiescence to cell proliferation corresponds to the transition from a stable steady state to sustained oscillations in the Cdk network. The transition depends on a finely tuned balance between factors that promote or hinder progression in the cell cycle. We show that the transition from quiescence to proliferation can occur in multiple ways that alter this balance. By resorting to bifurcation diagrams, we analyze the mechanism of oscillations in the Cdk network. Finally, we show that the complexity of the detailed model can be greatly reduced, without losing its key dynamical properties, by considering a skeleton model for the Cdk network. Using such a skeleton model for the mammalian cell cycle we show that positive feedback (PF) loops enhance the amplitude and the robustness of Cdk oscillations with respect to molecular noise. We compare the relative merits of the detailed and skeleton versions of the model for the Cdk network driving the mammalian cell cycle. PMID:23130001

Distinguishing low frequency oscillations within the 1/f spectral behaviour of electromagnetic brain signals.

PubMed

Demanuele, Charmaine; James, Christopher J; Sonuga-Barke, Edmund Js

2007-12-10

It has been acknowledged that the frequency spectrum of measured electromagnetic (EM) brain signals shows a decrease in power with increasing frequency. This spectral behaviour may lead to difficulty in distinguishing event-related peaks from ongoing brain activity in the electro- and magnetoencephalographic (EEG and MEG) signal spectra. This can become an issue especially in the analysis of low frequency oscillations (LFOs) - below 0.5 Hz - which are currently being observed in signal recordings linked with specific pathologies such as epileptic seizures or attention deficit hyperactivity disorder (ADHD), in sleep studies, etc. In this work we propose a simple method that can be used to compensate for this 1/f trend hence achieving spectral normalisation. This method involves filtering the raw measured EM signal through a differentiator prior to further data analysis. Applying the proposed method to various exemplary datasets including very low frequency EEG recordings, epileptic seizure recordings, MEG data and Evoked Response data showed that this compensating procedure provides a flat spectral base onto which event related peaks can be clearly observed. Findings suggest that the proposed filter is a useful tool for the analysis of physiological data especially in revealing very low frequency peaks which may otherwise be obscured by the 1/f spectral activity inherent in EEG/MEG recordings.

Force Control Is Related to Low-Frequency Oscillations in Force and Surface EMG

PubMed Central

Moon, Hwasil; Kim, Changki; Kwon, Minhyuk; Chen, Yen Ting; Onushko, Tanya; Lodha, Neha; Christou, Evangelos A.

2014-01-01

Force variability during constant force tasks is directly related to oscillations below 0.5 Hz in force. However, it is unknown whether such oscillations exist in muscle activity. The purpose of this paper, therefore, was to determine whether oscillations below 0.5 Hz in force are evident in the activation of muscle. Fourteen young adults (21.07±2.76 years, 7 women) performed constant isometric force tasks at 5% and 30% MVC by abducting the left index finger. We recorded the force output from the index finger and surface EMG from the first dorsal interosseous (FDI) muscle and quantified the following outcomes: 1) variability of force using the SD of force; 2) power spectrum of force below 2 Hz; 3) EMG bursts; 4) power spectrum of EMG bursts below 2 Hz; and 5) power spectrum of the interference EMG from 10–300 Hz. The SD of force increased significantly from 5 to 30% MVC and this increase was significantly related to the increase in force oscillations below 0.5 Hz (R 2 = 0.82). For both force levels, the power spectrum for force and EMG burst was similar and contained most of the power from 0–0.5 Hz. Force and EMG burst oscillations below 0.5 Hz were highly coherent (coherence = 0.68). The increase in force oscillations below 0.5 Hz from 5 to 30% MVC was related to an increase in EMG burst oscillations below 0.5 Hz (R 2 = 0.51). Finally, there was a strong association between the increase in EMG burst oscillations below 0.5 Hz and the interference EMG from 35–60 Hz (R 2 = 0.95). In conclusion, this finding demonstrates that bursting of the EMG signal contains low-frequency oscillations below 0.5 Hz, which are associated with oscillations in force below 0.5 Hz. PMID:25372038

Low-frequency blood pressure oscillations and inotrope treatment failure in premature infants.

PubMed

Vesoulis, Zachary A; Hao, Jessica; McPherson, Christopher; El Ters, Nathalie M; Mathur, Amit M

2017-07-01

The underlying mechanism as to why some hypotensive preterm infants do not respond to inotropic medications remains unclear. For these infants, we hypothesize that impaired vasomotor function is a significant factor and is manifested through a decrease in low-frequency blood pressure variability across regulatory components of vascular tone. Infants born ≤28 wk estimated gestational age underwent prospective recording of mean arterial blood pressure for 72 h after birth. After error correction, root-mean-square spectral power was calculated for each valid 10-min data frame across each of four frequency bands ( B1 , 0.005-0.0095 Hz; B2 , 0.0095-0.02 Hz; B3 , 0.02-0.06 Hz; and B4 , 0.06-0.16) corresponding to different components of vasomotion control. Forty infants (twenty-nine normotensive control and eleven inotrope-exposed) were included with a mean ± SD estimated gestational age of 25.2 ± 1.6 wk and birth weight 790 ± 211 g. 9.7/11.8 Million (82%) data points were error-free and used for analysis. Spectral power across all frequency bands increased with time, although the magnitude was 20% less in the inotrope-exposed infants. A statistically significant increase in spectral power in response to inotrope initiation was noted across all frequency bands. Infants with robust blood pressure response to inotropes had a greater increase compared with those who had limited or no blood pressure response. In this study, hypotensive infants who require inotropes have decreased low-frequency variability at baseline compared with normotensive infants, which increases after inotrope initiation. Low-frequency spectral power does not change for those with inotrope treatment failure, suggesting dysfunctional regulation of vascular tone as a potential mechanism of treatment failure. NEW & NOTEWORTHY In this study, we examine patterns of low-frequency oscillations in blood pressure variability across regulatory components of vascular tone in normotensive and

On the modulation of low-frequency quasi-periodic oscillations in black hole transients

NASA Astrophysics Data System (ADS)

Pawar, Devraj D.; Motta, Sara; Shanthi, K.; Bhattacharya, Dipankar; Belloni, Tomaso

2015-04-01

We studied the properties of the low-frequency quasi-periodic oscillations detected in a sample of six black hole candidates (XTE J1550-564, H 1743-322, XTE J1859+226, 4U 1630-47, GX 339-4, XTE J1650-500) observed by the Rossi XTE satellite. We analysed the relation between the full width at half-maximum and the frequency of all the narrow peaks detected in power density spectra where a type-C QPO is observed. Our goal was to understand the nature of the modulation of the signal by comparing the properties of different harmonic peaks in the power density spectrum. We find that for the sources in our sample the width of the fundamental and of the first harmonic are compatible with a frequency modulation, while that of the sub-harmonic is independent of frequency, possibly indicating the presence of an additional modulation in amplitude. We compare our results with those obtained earlier from GRS 1915+105 and XTE J1550-564.

Measurement of whole blood of different mammalian species in the oscillating shear field: influence of erythrocyte aggregation

NASA Astrophysics Data System (ADS)

Windberger, U.; Pöschl, Ch; Peters, S.; Huber, J.; van den Hoven, R.

2017-01-01

This is the first systematic analysis of mammalian blood of species with a high (horse), medium (man), and low (sheep) erythrocyte (RBC) aggregability by small amplitude oscillation technique. Amplitude and frequency sweep tests (linear viscoelastic mode) were performed with blood from healthy adult volunteers, horses, and sheep in CSS-mode. Blood samples were hematocrit (HCT) adjusted (40%, 50%, 60%) and tested at 7°C, 22°C, and 37°C. Generally, storage modulus (G´) increased with HCT and decreased with temperature in each species, but the gradient of this increase was species-specific. The lower dependency of G´ on the equine HCT value could be a benefit during physical performance when high numbers of RBCs are released from the spleen. In sheep, an HCT-threshold had to be overcome before the desired quasi-static condition of the blood sample could be achieved, suggesting that the contact between RBCs, and between RBCs and plasma molecules must be very low. The frequencies for tests under linear viscoelastic condition were in a narrow range around the physiologic heart rate of the species. In horse, time-dependent influences concurred at frequencies lower than 3 rad.s-1probably due to sedimentation of RBC aggregates. In conclusion, blood is a fragile suspension that shows its best stability around the resting heart rate of the species.

The effects of extra-low-frequency atmospheric pressure oscillations on human mental activity

NASA Astrophysics Data System (ADS)

Delyukov, A. A.; Didyk, L.

Slight atmospheric pressure oscillations (APO) in the extra-low-frequency range below 0.1 Hz, which frequently occur naturally, can influence human mental activity. This phenomenon has been observed in experiments with a group of 12 healthy volunteers exposed to experimentally created APO with amplitudes 30-50 Pa in the frequency band 0.011-0.17 Hz. Exposure of the subjects to APO for 15-30 min caused significant changes in attention and short-term memory functions, performance rate, and mental processing flexibility. The character of the response depended on the APO frequency and coherence. Periodic APO promoted purposeful mental activity, accompanied by an increase in breath-holding duration and a slower heart rate. On the other hand, quasi-chaotic APO, similar to the natural perturbations of atmospheric pressure, disrupted mental activity. These observations suggest that APO could be partly responsible for meteorosensitivity in humans.

Multimode and multistate ladder oscillator and frequency recognition device

NASA Technical Reports Server (NTRS)

Aumann, Herbert M. (Inventor)

1976-01-01

A ladder oscillator composed of capacitive and inductive impedances connected together to form a ladder network which has a chosen number N oscillation modes at N different frequencies. Each oscillation mode is characterized by a unique standing wave voltage pattern along the nodes of the ladder oscillator, with the mode in which the ladder oscillator is oscillating being determinable from the amplitudes or phase of the oscillations at the nodes. A logic circuit may be connected to the nodes of the oscillator to compare the phases of selected nodes and thereby determine which mode the oscillator is oscillating in. A ladder oscillator composed of passive capacitive and inductive impedances can be utilized as a frequency recognition device, since the passive ladder oscillator will display the characteristic standing wave patterns if an input signal impressed upon the ladder oscillator is close to one of the mode frequencies of the oscillator. A CL ladder oscillator having series capacitive impedances and shunt inductive impedances can exhibit sustained and autonomous oscillations if active nonlinear devices are connected in parallel with the shunt inductive impedances. The active CL ladder oscillator can be synchronized to input frequencies impressed upon the oscillator, and will continue to oscillate after the input signal has been removed at a mode frequency which is, in general, nearest to the input signal frequency. Autonomous oscillations may also be obtained as desired from the active CL ladder oscillator at the mode frequencies.

A low power cryocooled autonomous ultra-stable oscillator

NASA Astrophysics Data System (ADS)

Fluhr, C.; Dubois, B.; Grop, S.; Paris, J.; Le Tetû, G.; Giordano, V.

2016-12-01

We present the design and the preliminary evaluation of a cryostat equipped with a low power pulse-tube cryocooler intended to maintain near 5 K a high-Q factor sapphire microwave resonator. This cooled resonator constitutes the frequency reference of an ultra-stable oscillator presenting a short term fractional frequency stability of better than 1 ×10-15 . The proposed design enables to reach a state-of-the-art frequency stability with a cryogenic oscillator consuming only 3 kW of electrical power.

Automatic oscillator frequency control system

NASA Technical Reports Server (NTRS)

Smith, S. F. (Inventor)

1985-01-01

A frequency control system makes an initial correction of the frequency of its own timing circuit after comparison against a frequency of known accuracy and then sequentially checks and corrects the frequencies of several voltage controlled local oscillator circuits. The timing circuit initiates the machine cycles of a central processing unit which applies a frequency index to an input register in a modulo-sum frequency divider stage and enables a multiplexer to clock an accumulator register in the divider stage with a cyclical signal derived from the oscillator circuit being checked. Upon expiration of the interval, the processing unit compares the remainder held as the contents of the accumulator against a stored zero error constant and applies an appropriate correction word to a correction stage to shift the frequency of the oscillator being checked. A signal from the accumulator register may be used to drive a phase plane ROM and, with periodic shifts in the applied frequency index, to provide frequency shift keying of the resultant output signal. Interposition of a phase adder between the accumulator register and phase plane ROM permits phase shift keying of the output signal by periodic variation in the value of a phase index applied to one input of the phase adder.

High-frequency voltage oscillations in cultured astrocytes

PubMed Central

Fleischer, Wiebke; Theiss, Stephan; Slotta, Johannes; Holland, Christine; Schnitzler, Alfons

2015-01-01

Because of their close interaction with neuronal physiology, astrocytes can modulate brain function in multiple ways. Here, we demonstrate a yet unknown astrocytic phenomenon: Astrocytes cultured on microelectrode arrays (MEAs) exhibited extracellular voltage fluctuations in a broad frequency spectrum (100–600 Hz) after electrical stimulation. These aperiodic high-frequency oscillations (HFOs) could last several seconds and did not spread across the MEA. The voltage-gated calcium channel antagonist cilnidipine dose-dependently decreased the power of the oscillations. While intracellular calcium was pivotal, incubation with bafilomycin A1 showed that vesicular release of transmitters played only a minor role in the emergence of HFOs. Gap junctions and volume-regulated anionic channels had just as little functional impact, which was demonstrated by the addition of carbenoxolone (100 μmol/L) and NPPB (100 μmol/L). Hyperpolarization with low potassium in the extracellular solution (2 mmol/L) dramatically raised oscillation power. A similar effect was seen when we added extra sodium (+50 mmol/L) or if we replaced it with NMDG+ (50 mmol/L). The purinergic receptor antagonist PPADS suppressed the oscillation power, while the agonist ATP (100 μmol/L) had only an increasing effect when the bath solution pH was slightly lowered to pH 7.2. From these observations, we conclude that astrocytic voltage oscillations are triggered by activation of voltage-gated calcium channels and driven by a downstream influx of cations through channels that are permeable for large ions such as NMDG+. Most likely candidates are subtypes of pore-forming P2X channels with a low affinity for ATP. PMID:25969464

A novel optogenetically tunable frequency modulating oscillator

PubMed Central

2018-01-01

Synthetic biology has enabled the creation of biological reconfigurable circuits, which perform multiple functions monopolizing a single biological machine; Such a system can switch between different behaviours in response to environmental cues. Previous work has demonstrated switchable dynamical behaviour employing reconfigurable logic gate genetic networks. Here we describe a computational framework for reconfigurable circuits in E.coli using combinations of logic gates, and also propose the biological implementation. The proposed system is an oscillator that can exhibit tunability of frequency and amplitude of oscillations. Further, the frequency of operation can be changed optogenetically. Insilico analysis revealed that two-component light systems, in response to light within a frequency range, can be used for modulating the frequency of the oscillator or stopping the oscillations altogether. Computational modelling reveals that mixing two colonies of E.coli oscillating at different frequencies generates spatial beat patterns. Further, we show that these oscillations more robustly respond to input perturbations compared to the base oscillator, to which the proposed oscillator is a modification. Compared to the base oscillator, the proposed system shows faster synchronization in a colony of cells for a larger region of the parameter space. Additionally, the proposed oscillator also exhibits lesser synchronization error in the transient period after input perturbations. This provides a strong basis for the construction of synthetic reconfigurable circuits in bacteria and other organisms, which can be scaled up to perform functions in the field of time dependent drug delivery with tunable dosages, and sets the stage for further development of circuits with synchronized population level behaviour. PMID:29389936

A novel optogenetically tunable frequency modulating oscillator.

PubMed

Mahajan, Tarun; Rai, Kshitij

2018-01-01

Synthetic biology has enabled the creation of biological reconfigurable circuits, which perform multiple functions monopolizing a single biological machine; Such a system can switch between different behaviours in response to environmental cues. Previous work has demonstrated switchable dynamical behaviour employing reconfigurable logic gate genetic networks. Here we describe a computational framework for reconfigurable circuits in E.coli using combinations of logic gates, and also propose the biological implementation. The proposed system is an oscillator that can exhibit tunability of frequency and amplitude of oscillations. Further, the frequency of operation can be changed optogenetically. Insilico analysis revealed that two-component light systems, in response to light within a frequency range, can be used for modulating the frequency of the oscillator or stopping the oscillations altogether. Computational modelling reveals that mixing two colonies of E.coli oscillating at different frequencies generates spatial beat patterns. Further, we show that these oscillations more robustly respond to input perturbations compared to the base oscillator, to which the proposed oscillator is a modification. Compared to the base oscillator, the proposed system shows faster synchronization in a colony of cells for a larger region of the parameter space. Additionally, the proposed oscillator also exhibits lesser synchronization error in the transient period after input perturbations. This provides a strong basis for the construction of synthetic reconfigurable circuits in bacteria and other organisms, which can be scaled up to perform functions in the field of time dependent drug delivery with tunable dosages, and sets the stage for further development of circuits with synchronized population level behaviour.

U.S. Hail Frequency and the Global Wind Oscillation

NASA Astrophysics Data System (ADS)

Gensini, Vittorio A.; Allen, John T.

2018-02-01

Changes in Earth relative atmospheric angular momentum can be described by an index known as the Global Wind Oscillation. This global index accounts for changes in Earth's atmospheric budget of relative angular momentum through interactions of tropical convection anomalies, extratropical dynamics, and engagement of surface torques (e.g., friction and mountain). It is shown herein that U.S. hail events are more (less) likely to occur in low (high) atmospheric angular momentum base states when excluding weak Global Wind Oscillation days, with the strongest relationships found in the boreal spring and fall. Severe, significant severe, and giant hail events are more likely to occur during Global Wind Oscillation phases 8, 1, 2, and 3 during the peak of U.S. severe weather season. Lower frequencies of hail events are generally found in Global Wind Oscillation phases 4-7 but vary based on Global Wind Oscillation amplitude and month. In addition, probabilistic anomalies of atmospheric ingredients supportive of hail producing supercell thunderstorms closely mimic locations of reported hail frequency, helping to corroborate report results.

REPRODUCING THE CORRELATIONS OF TYPE C LOW-FREQUENCY QUASI-PERIODIC OSCILLATION PARAMETERS IN XTE J1550–564 WITH A SPIRAL STRUCTURE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Varniere, Peggy; Vincent, Frederic H., E-mail: varniere@apc.univ-paris7.fr

While it has been observed that the parameters intrinsic to the type C low-frequency quasi-periodic oscillations are related in a nonlinear manner among themselves, there has been, up to now, no model to explain or reproduce how the frequency, the FWHM, and the rms amplitude of the type C low-frequency quasi-periodic oscillations behave with respect to one another. Here we are using a simple toy model representing the emission from a standard disk and a spiral such as that caused by the accretion–ejection instability to reproduce the overall observed behavior and shed some light on its origin. This allows usmore » to prove the ability of such a spiral structure to be at the origin of flux modulation over more than an order of magnitude in frequency.« less

High spectral purity Kerr frequency comb radio frequency photonic oscillator

PubMed Central

Liang, W.; Eliyahu, D.; Ilchenko, V. S.; Savchenkov, A. A.; Matsko, A. B.; Seidel, D.; Maleki, L.

2015-01-01

Femtosecond laser-based generation of radio frequency signals has produced astonishing improvements in achievable spectral purity, one of the basic features characterizing the performance of an radio frequency oscillator. Kerr frequency combs hold promise for transforming these lab-scale oscillators to chip-scale level. In this work we demonstrate a miniature 10 GHz radio frequency photonic oscillator characterized with phase noise better than −60 dBc Hz−1 at 10 Hz, −90 dBc Hz−1 at 100 Hz and −170 dBc Hz−1 at 10 MHz. The frequency stability of this device, as represented by Allan deviation measurements, is at the level of 10−10 at 1–100 s integration time—orders of magnitude better than existing radio frequency photonic devices of similar size, weight and power consumption. PMID:26260955

Twin peak high-frequency quasi-periodic oscillations as a spectral imprint of dual oscillation modes of accretion tori

NASA Astrophysics Data System (ADS)

Bakala, P.; Goluchová, K.; Török, G.; Šrámková, E.; Abramowicz, M. A.; Vincent, F. H.; Mazur, G. P.

2015-09-01

Context. High-frequency (millisecond) quasi-periodic oscillations (HF QPOs) are observed in the X-ray power-density spectra of several microquasars and low-mass X-ray binaries. Two distinct QPO peaks, so-called twin peak QPOs, are often detected simultaneously exhibiting their frequency ratio close or equal to 3:2. A widely discussed class of proposed QPOs models is based on oscillations of accretion toroidal structures orbiting in the close vicinity of black holes or neutron stars. Aims: Following the analytic theory and previous studies of observable spectral signatures, we aim to model the twin peak QPOs as a spectral imprint of specific dual oscillation regime defined by a combination of the lowest radial and vertical oscillation mode of slender tori. We consider the model of an optically thick slender accretion torus with constant specific angular momentum. We examined power spectra and fluorescent Kα iron line profiles for two different simulation setups with the mode frequency relations corresponding to the epicyclic resonance HF QPOs model and modified relativistic precession QPOs model. Methods: We used relativistic ray-tracing implemented in the parallel simulation code LSDplus. In the background of the Kerr spacetime geometry, we analyzed the influence of the distant observer inclination and the spin of the central compact object. Relativistic optical projection of the oscillating slender torus is illustrated by images in false colours related to the frequency shift. Results: We show that performed simulations yield power spectra with the pair of dominant peaks that correspond to the frequencies of radial and vertical oscillation modes and with the peak frequency ratio equal to the proper value 3:2 on a wide range of inclinations and spin values. We also discuss exceptional cases of a very low and very high inclination, as well as unstable high spin relativistic precession-like configurations that predict a constant frequency ratio equal to 1:2. We

Parkinsonian Rest Tremor Is Associated With Modulations of Subthalamic High-Frequency Oscillations.

PubMed

Hirschmann, Jan; Butz, Markus; Hartmann, Christian J; Hoogenboom, Nienke; Özkurt, Tolga E; Vesper, Jan; Wojtecki, Lars; Schnitzler, Alfons

2016-10-01

High frequency oscillations (>200 Hz) have been observed in the basal ganglia of PD patients and were shown to be modulated by the administration of levodopa and voluntary movement. The objective of this study was to test whether the power of high-frequency oscillations in the STN is associated with spontaneous manifestation of parkinsonian rest tremor. The electromyogram of both forearms and local field potentials from the STN were recorded in 11 PD patients (10 men, age 58 [9.4] years, disease duration 9.2 [6.3] years). Patients were recorded at rest and while performing repetitive hand movements before and after levodopa intake. High-frequency oscillation power was compared across epochs containing rest tremor, tremor-free rest, or voluntary movement and related to the tremor cycle. We observed prominent slow (200-300 Hz) and fast (300-400 Hz) high-frequency oscillations. The ratio between slow and fast high-frequency oscillation power increased when tremor became manifest. This increase was consistent across nuclei (94%) and occurred in medication ON and OFF. The ratio outperformed other potential markers of tremor, such as power at individual tremor frequency, beta power, or low gamma power. For voluntary movement, we did not observe a significant difference when compared with rest or rest tremor. Finally, rhythmic modulations of high-frequency oscillation power occurred within the tremor cycle. Subthalamic high-frequency oscillation power is closely linked to the occurrence of parkinsonian rest tremor. The balance between slow and fast high-frequency oscillation power combines information on motor and medication state. © 2016 International Parkinson and Movement Disorder Society. © 2016 International Parkinson and Movement Disorder Society.

CROSS-DISCIPLINARY PHYSICS AND RELATED AREAS OF SCIENCE AND TECHNOLOGY: A new mammalian circadian oscillator model including the cAMP module

NASA Astrophysics Data System (ADS)

Wang, Jun-Wei; Zhou, Tian-Shou

2009-12-01

In this paper, we develop a new mathematical model for the mammalian circadian clock, which incorporates both transcriptional/translational feedback loops (TTFLs) and a cAMP-mediated feedback loop. The model shows that TTFLs and cAMP signalling cooperatively drive the circadian rhythms. It reproduces typical experimental observations with qualitative similarities, e.g. circadian oscillations in constant darkness and entrainment to light-dark cycles. In addition, it can explain the phenotypes of cAMP-mutant and Rev-erbα-/--mutant mice, and help us make an experimentally-testable prediction: oscillations may be rescued when arrhythmic mice with constitutively low concentrations of cAMP are crossed with Rev-erbα-/- mutant mice. The model enhances our understanding of the mammalian circadian clockwork from the viewpoint of the entire cell.

High frequency oscillations in brain hemodynamic response

NASA Astrophysics Data System (ADS)

Akin, Ata; Bolay, Hayrunnisa

2007-07-01

Tight autoregulation of vessel tone guarantees proper delivery of nutrients to the tissues. This regulation is maintained at a more delicate level in the brain since any decrease in the supply of glucose and oxygen to neuronal tissues might lead to unrecoverable injury. Functional near infrared spectroscopy has been proposed as a new tool to monitor the cerebrovascular response during cognitive activity. We have observed that during a Stroop task three distinct oscillatory patterns govern the control of the cerebrovascular reactivity: very low frequency (0.02-0.05 Hz), low frequency (0.08-0.12 Hz) and high frequency (0.12-0.18 Hz). High frequency oscillations have been shown to be related to stress level of the subjects. Our findings indicate that as the stress level is increased so does the energy of the high frequency component indicating a higher stimulation from the autonomic nervous system.

Oscillations in motor unit discharge are reflected in the low-frequency component of rectified surface EMG and the rate of change in force.

PubMed

Yoshitake, Yasuhide; Shinohara, Minoru

2013-11-01

Common drive to a motor unit (MU) pool manifests as low-frequency oscillations in MU discharge rate, producing fluctuations in muscle force. The aim of the study was to examine the temporal correlation between instantaneous MU discharge rate and rectified EMG in low frequencies. Additionally, we attempted to examine whether there is a temporal correlation between the low-frequency oscillations in MU discharge rate and the first derivative of force (dF/dt). Healthy young subjects produced steady submaximal force with their right finger as a single task or while maintaining a pinch-grip force with the left hand as a dual task. Surface EMG and fine-wire MU potentials were recorded from the first dorsal interosseous muscle in the right hand. Surface EMG was band-pass filtered (5-1,000 Hz) and full-wave rectified. Rectified surface EMG and the instantaneous discharge rate of MUs were smoothed by a Hann-window of 400 ms duration (equivalent to 2 Hz low-pass filtering). In each of the identified MUs, the smoothed MU discharge rate was positively correlated with the rectified-and-smoothed EMG as confirmed by the distinct peak in cross-correlation function with greater values in the dual task compared with the single task. Additionally, the smoothed MU discharge rate was temporally correlated with dF/dt more than with force and with rectified-and-smoothed EMG. The results indicated that the low-frequency component of rectified surface EMG and the first derivative of force provide temporal information on the low-frequency oscillations in the MU discharge rate.

Low-Frequency Flow Oscillations on Stalled Wings Exhibiting Cellular Separation Topology

NASA Astrophysics Data System (ADS)

Disotell, Kevin James

One of the most pervasive threats to aircraft controllability is wing stall, a condition associated with loss of lift due to separation of air flow from the wing surface at high angles of attack. A recognized need for improved upset recovery training in extended-envelope flight simulators is a physical understanding of the post-stall aerodynamic environment, particularly key flow phenomena which influence the vehicle trajectory. Large-scale flow structures known as stall cells, which scale with the wing chord and are spatially-periodic along the span, have been previously observed on post-stall airfoils with trailing-edge separation present. Despite extensive documentation of stall cells in the literature, the physical mechanisms behind their formation and evolution have proven to be elusive. The undertaken study has sought to characterize the inherently turbulent separated flow existing above the wing surface with cell formation present. In particular, the question of how the unsteady separated flow may interact with the wing to produce time-averaged cellular surface patterns is considered. Time-resolved, two-component particle image velocimetry measurements were acquired at the plane of symmetry of a single stall cell formed on an extruded NACA 0015 airfoil model at chord Reynolds number of 560,000 to obtain insight into the time-dependent flow structure. The evolution of flow unsteadiness was analyzed over a static angle-of-attack range covering the narrow post-stall regime in which stall cells have been observed. Spectral analysis of velocity fields acquired near the stall angle confirmed a low-frequency flow oscillation previously detected in pointwise surface measurements by Yon and Katz (1998), corresponding to a Strouhal number of 0.042 based on frontal projected chord height. Probability density functions of the streamwise velocity component were used to estimate the convective speed of this mode at approximately half the free-stream velocity, in agreement

North-south asymmetry of ultra-low-frequency oscillations of Earth's electromagnetic field

NASA Astrophysics Data System (ADS)

Guglielmi, Anatol; Klain, Boris; Potapov, Alexander

2017-12-01

In the paper, we present the result of an experimental study of north-south asymmetry of ultralow-frequency electromagnetic oscillations IPCL. This study is based on observations made at Mirny Observatory (Antarctica). IPCLs are excited in the dayside sector of the auroral oval in the range 3-10 min periods and represent one of the most powerful types of oscillations of Earth's magnetosphere. These oscillations were discovered in the 1970s during IPhE AS USSR polar expeditions organized by Prof. V.A. Troitskaya. We have shown that IPCL activity in Mirny depends on the inclination (north-south asymmetry) of interplanetary magnetic field (IMF) lines to the plane of the geomagnetic equator before the front of the magnetosphere. The result suggests a controlling exposure of IMF on the magnetospheric oscillations and gives rise to the hypothesis that IPCLs are forced oscillations of a nonlinear dynamical system whose major structural elements are dayside polar cusps. The paper is dedicated to the memory of Professor V.A. Troitskaya (1917-2010).

Frequency jumps in single chip microwave LC oscillators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gualco, Gabriele; Grisi, Marco; Boero, Giovanni, E-mail: giovanni.boero@epfl.ch

2014-12-15

We report on the experimental observation of oscillation frequency jumps in microwave LC oscillators fabricated using standard complementary metal-oxide-semiconductor technologies. The LC oscillators, operating at a frequency of about 20 GHz, consist of a single turn planar coil, a metal-oxide-metal capacitor, and two cross-coupled metal-oxide-semiconductor field effect transistors used as negative resistance network. At 300 K as well as at 77 K, the oscillation frequency is a continuous function of the oscillator bias voltage. At 4 K, frequency jumps as large as 30 MHz are experimentally observed. This behavior is tentatively attributed to the emission and capture of single electrons from defects andmore » dopant atoms.« less

High frequency oscillations evoked by peripheral magnetic stimulation.

PubMed

Biller, S; Simon, L; Fiedler, P; Strohmeier, D; Haueisen, J

2011-01-01

The analysis of somatosensory evoked potentials (SEP) and / or fields (SEF) is a well-established and important tool for investigating the functioning of the peripheral and central human nervous system. A standard technique to evoke SEPs / SEFs is the stimulation of the median nerve by using a bipolar electrical stimulus. We aim at an alternative stimulation technique enabling stimulation of deep nerve structures while reducing patient stress and error susceptibility. In the current study, we apply a commercial transcranial magnetic stimulation system for peripheral magnetic stimulation of the median nerve. We compare the results of simultaneously recorded EEG signals to prove applicability of our technique to evoke SEPs including low frequency components (LFC) as well as high frequency oscillations (HFO). Therefore, we compare amplitude, latency and time-frequency characteristics of the SEP of 14 healthy volunteers after electric and magnetic stimulation. Both low frequency components and high frequency oscillations were detected. The HFOs were superimposed onto the primary cortical response N20. Statistical analysis revealed significantly lower amplitudes and increased latencies for LFC and HFO components after magnetic stimulation. The differences indicate the inability of magnetic stimulation to elicit supramaximal responses. A psycho-perceptual evaluation showed that magnetic stimulation was less unpleasant for 12 out of the 14 volunteers. In conclusion, we showed that LFC and HFO components related to median nerve stimulation can be evoked by peripheral magnetic stimulation.

Temperature as a universal resetting cue for mammalian circadian oscillators.

PubMed

Buhr, Ethan D; Yoo, Seung-Hee; Takahashi, Joseph S

2010-10-15

Environmental temperature cycles are a universal entraining cue for all circadian systems at the organismal level with the exception of homeothermic vertebrates. We report here that resistance to temperature entrainment is a property of the suprachiasmatic nucleus (SCN) network and is not a cell-autonomous property of mammalian clocks. This differential sensitivity to temperature allows the SCN to drive circadian rhythms in body temperature, which can then act as a universal cue for the entrainment of cell-autonomous oscillators throughout the body. Pharmacological experiments show that network interactions in the SCN are required for temperature resistance and that the heat shock pathway is integral to temperature resetting and temperature compensation in mammalian cells. These results suggest that the evolutionarily ancient temperature resetting response can be used in homeothermic animals to enhance internal circadian synchronization.

Frequency stability improvement for piezoresistive micromechanical oscillators via synchronization

NASA Astrophysics Data System (ADS)

Pu, Dong; Huan, Ronghua; Wei, Xueyong

2017-03-01

Synchronization phenomenon first discovered in Huygens' clock shows that the rhythms of oscillating objects can be adjusted via an interaction. Here we show that the frequency stability of a piezoresistive micromechanical oscillator can be enhanced via synchronization. The micromechanical clamped-clamped beam oscillator is built up using the electrostatic driving and piezoresistive sensing technique and the synchronization phenomenon is observed after coupling it to an external oscillator. An enhancement of frequency stability is obtained in the synchronization state. The influences of the synchronizing perturbation intensity and frequency detuning applied on the oscillator are studied experimentally. A theoretical analysis of phase noise leads to an analytical formula for predicting Allan deviation of the frequency output of the piezoresistive oscillator, which successfully explains the experimental observations and the mechanism of frequency stability enhancement via synchronization.

Filterless low-phase-noise frequency-quadrupled microwave generation based on a multimode optoelectronic oscillator

NASA Astrophysics Data System (ADS)

Teng, Yichao; Zhang, Pin; Zhang, Baofu; Chen, Yiwang

2018-02-01

A scheme to realize low-phase-noise frequency-quadrupled microwave generation without any filter is demonstrated. In this scheme, a multimode optoelectronic oscillator is mainly contributed by dual-parallel Mach-Zehnder modulators, fiber, photodetector, and microwave amplifier. The local source signal is modulated by a child MZM (MZMa), which is worked at maximum transmission point. Through properly adjusting the bias voltages of the other child MZM (MZMb) and the parent MZM (MZMc), optical carrier is effectively suppressed and second sidebands are retained, then the survived optical signal is fed back to the photodetector and MZMb to form an optoelectronic hybrid resonator and realize frequency-quadrupled signal generation. Due to the high Q-factor and mode selection effect of the optoelectronic hybrid resonator, compared with the source signal, the generated frequency-quadrupled signal has a lower phase noise. The approach has verified by experiments, and 18, 22, and 26 GHz frequency-quadrupled signal are generated by 4.5, 5.5, and 6.5 GHz local source signals. Compared with 4.5 GHz source signal, the phase noise of generated 18 GHz signal at 10 kHz frequency offset has 26.5 dB reduction.

Temperature as a universal resetting cue for mammalian circadian oscillators

PubMed Central

Buhr, Ethan D.; Yoo, Seung-Hee; Takahashi, Joseph S.

2011-01-01

Environmental temperature cycles are a universal entraining cue for all circadian systems at the organismal level with the exception of homeothermic vertebrates. We report here that resistance to temperature entrainment is a property of the suprachiasmatic nucleus (SCN) network and is not a cell autonomous property of mammalian clocks. This differential sensitivity to temperature allows the SCN to drive circadian rhythms in body temperature which can then act as a universal cue for the entrainment of cell autonomous oscillators throughout the body. Pharmacological experiments show that network interactions in the SCN are required for temperature resistance and that the heat shock pathway is integral to temperature resetting and temperature compensation in mammalian cells. These results suggest that the evolutionarily ancient temperature resetting response can be utilized in homeothermic animals to enhance internal circadian synchronization. PMID:20947768

ON THE GEOMETRIC NATURE OF LOW-FREQUENCY QUASI-PERIODIC OSCILLATIONS IN NEUTRON-STAR LOW-MASS X-RAY BINARIES

DOE Office of Scientific and Technical Information (OSTI.GOV)

Homan, Jeroen; Remillard, Ronald A.; Fridriksson, Joel K., E-mail: jeroen@space.mit.edu

2015-10-10

We report on a detailed analysis of the so-called ∼1 Hz quasi-periodic oscillation (QPO) in the eclipsing and dipping neutron-star low-mass X-ray binary EXO 0748–676. This type of QPO has previously been shown to have a geometric origin. Our study focuses on the evolution of the QPO as the source moves through the color–color diagram in which it traces out an atoll-source-like track. The QPO frequency increases from ∼0.4 Hz in the hard state to ∼25 Hz as the source approaches the soft state. Combining power spectra based on QPO frequency reveals additional features that strongly resemble those seen inmore » non-dipping/eclipsing atoll sources. We show that the low-frequency QPOs in atoll sources and the ∼1 Hz QPO in EXO 0748–676 follow similar relations with respect to the noise components in their power spectra. We conclude that the frequencies of both types of QPOs are likely set by (the same) precession of a misaligned inner accretion disk. For high-inclination systems like EXO 0748–676 this results in modulations of the neutron-star emission due to obscuration or scattering, while for lower-inclination systems the modulations likely arise from relativistic Doppler-boosting and light-bending effects.« less

Magnetoquantum Oscillations at THz Frequencies in InSb.

PubMed

Gogoi, P; Kamenskyi, D; Arslanov, D D; Jongma, R T; van der Zande, W J; Redlich, B; van der Meer, A F G; Engelkamp, H; Christianen, P C M; Maan, J C

2017-10-06

The ac magnetoconductance of bulk InSb at THz frequencies in high magnetic fields, as measured by the transmission of THz radiation, shows a field-induced transmission, which at high temperatures (≈100  K) is well explained with classical magnetoplasma effects (helicon waves). However, at low temperatures (4 K), the transmitted radiation intensity shows magnetoquantum oscillations that represent the Shubnikov-de Haas effect at THz frequencies. At frequencies above 0.9 THz, when the radiation period is shorter than the Drude scattering time, an anomalously high transmission is observed in the magnetic quantum limit that can be interpreted as carrier localization at high frequencies.

Magnetoquantum Oscillations at THz Frequencies in InSb

NASA Astrophysics Data System (ADS)

Gogoi, P.; Kamenskyi, D.; Arslanov, D. D.; Jongma, R. T.; van der Zande, W. J.; Redlich, B.; van der Meer, A. F. G.; Engelkamp, H.; Christianen, P. C. M.; Maan, J. C.

2017-10-01

The ac magnetoconductance of bulk InSb at THz frequencies in high magnetic fields, as measured by the transmission of THz radiation, shows a field-induced transmission, which at high temperatures (≈100 K ) is well explained with classical magnetoplasma effects (helicon waves). However, at low temperatures (4 K), the transmitted radiation intensity shows magnetoquantum oscillations that represent the Shubnikov-de Haas effect at THz frequencies. At frequencies above 0.9 THz, when the radiation period is shorter than the Drude scattering time, an anomalously high transmission is observed in the magnetic quantum limit that can be interpreted as carrier localization at high frequencies.

The mechanism of growth of the low-frequency East Asia-Pacific teleconnection and the triggering role of tropical intraseasonal oscillation

NASA Astrophysics Data System (ADS)

Wang, Jiabao; Wen, Zhiping; Wu, Renguang; Guo, Yuanyuan; Chen, Zesheng

2016-06-01

The East Asia-Pacific (EAP) pattern is a well-known meridional teleconnection over East Asia during boreal summer. In this study, the mechanism for growth of the EAP on intraseasonal timescale is investigated through a vorticity budget. It is found that the beta-effect and high-frequency transient eddies have primary contributions to the growth of the low-frequency EAP. The former leads to a westward shift of disturbances associated with the low-frequency EAP and the latter favors an amplification of disturbances, respectively. The interaction between low-frequency disturbances and zonal flow has a damping effect by dragging disturbances eastward. The impact of boreal summer intraseasonal oscillation (BSISO) on the triggering of the low-frequency EAP is also examined in this study based on observational analysis and a linear model experiment. It is shown that an elongated anomalous convection band located in the vicinity of Philippines associated with the dominant mode of BSISO has a significant impact on the initiation of low-frequency EAP via Rossby wave propagation, whereas anomalous convection located over the North Indian Ocean has a limited impact. Based on the results of present study, the low-frequency EAP could be a self-sustained mode, and the BSISO plays a substantial role in triggering the low-frequency EAP.

Thin-film piezoelectric-on-silicon resonators for high-frequency reference oscillator applications.

PubMed

Abdolvand, Reza; Lavasani, Hossein M; Ho, Gavin K; Ayazi, Farrokh

2008-12-01

This paper studies the application of lateral bulk acoustic thin-film piezoelectric-on-substrate (TPoS) resonators in high-frequency reference oscillators. Low-motional-impedance TPoS resonators are designed and fabricated in 2 classes--high-order and coupled-array. Devices of each class are used to assemble reference oscillators and the performance characteristics of the oscillators are measured and discussed. Since the motional impedance of these devices is small, the transimpedance amplifier (TIA) in the oscillator loop can be reduced to a single transistor and 3 resistors, a format that is very power-efficient. The lowest reported power consumption is approximately 350 microW for an oscillator operating at approximately 106 MHz. A passive temperature compensation method is also utilized by including the buried oxide layer of the silicon-on-insulator (SOI) substrate in the structural resonant body of the device, and a very small (-2.4 ppm/ degrees C) temperature coefficient of frequency is obtained for an 82-MHz oscillator.

WAMS measurements pre-processing for detecting low-frequency oscillations in power systems

NASA Astrophysics Data System (ADS)

Kovalenko, P. Y.

2017-07-01

Processing the data received from measurement systems implies the situation when one or more registered values stand apart from the sample collection. These values are referred to as “outliers”. The processing results may be influenced significantly by the presence of those in the data sample under consideration. In order to ensure the accuracy of low-frequency oscillations detection in power systems the corresponding algorithm has been developed for the outliers detection and elimination. The algorithm is based on the concept of the irregular component of measurement signal. This component comprises measurement errors and is assumed to be Gauss-distributed random. The median filtering is employed to detect the values lying outside the range of the normally distributed measurement error on the basis of a 3σ criterion. The algorithm has been validated involving simulated signals and WAMS data as well.

Dynamic modulation of epileptic high frequency oscillations by the phase of slower cortical rhythms.

PubMed

Ibrahim, George M; Wong, Simeon M; Anderson, Ryan A; Singh-Cadieux, Gabrielle; Akiyama, Tomoyuki; Ochi, Ayako; Otsubo, Hiroshi; Okanishi, Tohru; Valiante, Taufik A; Donner, Elizabeth; Rutka, James T; Snead, O Carter; Doesburg, Sam M

2014-01-01

Pathological high frequency oscillations (pHFOs) have been proposed to be robust markers of epileptic cortex. Oscillatory activity below this frequency range has been shown to be modulated by phase of lower frequency oscillations. Here, we tested the hypothesis that dynamic cross-frequency interactions involving pHFOs are concentrated within the epileptogenic cortex. Intracranial electroencephalographic recordings from 17 children with medically-intractable epilepsy secondary to focal cortical dysplasia were obtained. A time-resolved analysis was performed to determine topographic concentrations and dynamic changes in cross-frequency amplitude-to-phase coupling (CFC). CFC between pHFOs and the phase of theta and alpha rhythms was found to be significantly elevated in the seizure-onset zone compared to non-epileptic regions (p<0.01). Data simulations showed that elevated CFC could not be attributed to the presence of sharp transients or other signal properties. The phase of low frequency oscillations at which pHFO amplitudes were maximal was inconsistent at seizure initiation, yet consistently at the trough of the low frequency rhythm at seizure termination. Amplitudes of pHFOs were most significantly modulated by the phase of alpha-band oscillations (p<0.01). These results suggest that increased CFC between pHFO amplitude and alpha phase may constitute a marker of epileptogenic brain areas and may be relevant for understanding seizure dynamics. Copyright © 2013 Elsevier Inc. All rights reserved.

Frequency transitions in odor-evoked neural oscillations.

PubMed

Ito, Iori; Bazhenov, Maxim; Ong, Rose Chik-ying; Raman, Baranidharan; Stopfer, Mark

2009-12-10

In many species, sensory stimuli elicit the oscillatory synchronization of groups of neurons. What determines the properties of these oscillations? In the olfactory system of the moth, we found that odors elicited oscillatory synchronization through a neural mechanism like that described in locust and Drosophila. During responses to long odor pulses, oscillations suddenly slowed as net olfactory receptor neuron (ORN) output decreased; thus, stimulus intensity appeared to determine oscillation frequency. However, changing the concentration of the odor had little effect upon oscillatory frequency. Our recordings in vivo and computational models based on these results suggested that the main effect of increasing odor concentration was to recruit additional, less well-tuned ORNs whose firing rates were tightly constrained by adaptation and saturation. Thus, in the periphery, concentration is encoded mainly by the size of the responsive ORN population, and oscillation frequency is set by the adaptation and saturation of this response.

Chip Scale Atomic Resonator Frequency Stabilization System With Ultra-Low Power Consumption for Optoelectronic Oscillators.

PubMed

Zhao, Jianye; Zhang, Yaolin; Lu, Haoyuan; Hou, Dong; Zhang, Shuangyou; Wang, Zhong

2016-07-01

We present a long-term chip scale stabilization scheme for optoelectronic oscillators (OEOs) based on a rubidium coherent population trapping (CPT) atomic resonator. By locking a single mode of an OEO to the (85)Rb 3.035-GHz CPT resonance utilizing an improved phase-locked loop (PLL) with a PID regulator, we achieved a chip scale frequency stabilization system for the OEO. The fractional frequency stability of the stabilized OEO by overlapping Allan deviation reaches 6.2 ×10(-11) (1 s) and  ∼ 1.45 ×10 (-11) (1000 s). This scheme avoids a decrease in the extra phase noise performance induced by the electronic connection between the OEO and the microwave reference in common injection locking schemes. The total physical package of the stabilization system is [Formula: see text] and the total power consumption is 400 mW, which provides a chip scale and portable frequency stabilization approach with ultra-low power consumption for OEOs.

High frequency nanotube oscillator

DOEpatents

Peng, Haibing [Houston, TX; Zettl, Alexander K [Kensington, TX

2012-02-21

A tunable nanostructure such as a nanotube is used to make an electromechanical oscillator. The mechanically oscillating nanotube can be provided with inertial clamps in the form of metal beads. The metal beads serve to clamp the nanotube so that the fundamental resonance frequency is in the microwave range, i.e., greater than at least 1 GHz, and up to 4 GHz and beyond. An electric current can be run through the nanotube to cause the metal beads to move along the nanotube and changing the length of the intervening nanotube segments. The oscillator can operate at ambient temperature and in air without significant loss of resonance quality. The nanotube is can be fabricated in a semiconductor style process and the device can be provided with source, drain, and gate electrodes, which may be connected to appropriate circuitry for driving and measuring the oscillation. Novel driving and measuring circuits are also disclosed.

Frequency transitions in odor-evoked neural oscillations

PubMed Central

Ito, Iori; Bazhenov, Maxim; Ong, Rose Chik-ying; Raman, Baranidharan; Stopfer, Mark

2009-01-01

Summary In many species sensory stimuli elicit the oscillatory synchronization of groups of neurons. What determines the properties of these oscillations? In the olfactory system of the moth we found that odors elicited oscillatory synchronization through a neural mechanism like that described in locust and Drosophila. During responses to long odor pulses, oscillations suddenly slowed as net olfactory receptor neuron (ORN) output decreased; thus, stimulus intensity appeared to determine oscillation frequency. However, changing the concentration of the odor had little effect upon oscillatory frequency. Our recordings in vivo and computational models based on these results suggested the main effect of increasing odor concentration was to recruit additional, less well-tuned ORNs whose firing rates were tightly constrained by adaptation and saturation. Thus, in the periphery, concentration is encoded mainly by the size of the responsive ORN population, and oscillation frequency is set by the adaptation and saturation of this response. PMID:20005825

Testing the relativistic precession model using low-frequency and kHz quasi-periodic oscillations in neutron star low-mass X-ray binaries with known spin

NASA Astrophysics Data System (ADS)

van Doesburgh, Marieke; van der Klis, Michiel

2017-03-01

We analyse all available RXTE data on a sample of 13 low-mass X-ray binaries with known neutron star spin that are not persistent pulsars. We carefully measure the correlations between the centroid frequencies of the quasi-periodic oscillations (QPOs). We compare these correlations to the prediction of the relativistic precession model that, due to frame dragging, a QPO will occur at the Lense-Thirring precession frequency νLT of a test-particle orbit whose orbital frequency is the upper kHz QPO frequency νu. Contrary to the most prominent previous studies, we find two different oscillations in the range predicted for νLT that are simultaneously present over a wide range of νu. Additionally, one of the low-frequency noise components evolves into a (third) QPO in the νLT range when νu exceeds 600 Hz. The frequencies of these QPOs all correlate to νu following power laws with indices between 0.4 and 3.3, significantly exceeding the predicted value of 2.0 in 80 per cent of the cases (at 3 to >20σ). Also, there is no evidence that the neutron star spin frequency affects any of these three QPO frequencies, as would be expected for frame dragging. Finally, the observed QPO frequencies tend to be higher than the νLT predicted for reasonable neutron star specific moment of inertia. In the light of recent successes of precession models in black holes, we briefly discuss ways in which such precession can occur in neutron stars at frequencies different from test-particle values and consistent with those observed. A precessing torus geometry and other torques than frame dragging may allow precession to produce the observed frequency correlations, but can only explain one of the three QPOs in the νLT range.

Coupled Optoelectronic Oscillators:. Application to Low-Jitter Pulse Generation

NASA Astrophysics Data System (ADS)

Yu, N.; Tu, M.; Maleki, L.

2002-04-01

Actively mode-locked Erbium-doped fiber lasers (EDFL) have been studied for generating stable ultra-fast pulses (< 2 ps) at high repetition rates (> 5 GHz) [1,2]. These devices can be compact and environmentally stable, quite suitable for fiber-based high-data-rate communications and optical ultra-fast analog-to-digital conversions (ADC) [3]. The pulse-to-pulse jitter of an EDFL-based pulse generator will be ultimately limited by the phase noise of the mode-locking microwave source (typically electronic frequency synthesizers). On the other hand, opto-electronic oscillators (OEO) using fibers have been demonstrated to generate ultra-low phase noise microwaves at 10 GHz and higher [4]. The overall phase noise of an OEO can be much lower than commercially available synthesizers at the offset-frequency range above 100 Hz. Clearly, ultra-low jitter pulses can be generated by taking advantage of the low phase noise of OEOs. In this paper, we report the progress in developing a new low-jitter pulse generator by combing the two technologies. In our approach, the optical oscillator (mode-locked EDFL) and the microwave oscillator (OEO) are coupled through a common Mach-Zehnder (MZ) modulator, thus named coupled opto-electronic oscillator (COEO) [5]. Based on the results of previous OEO study, we can expect a 10 GHz pulse train with jitters less than 10 fs.

Synchronization, non-linear dynamics and low-frequency fluctuations: Analogy between spontaneous brain activity and networked single-transistor chaotic oscillators

PubMed Central

Minati, Ludovico; Chiesa, Pietro; Tabarelli, Davide; D'Incerti, Ludovico

2015-01-01

In this paper, the topographical relationship between functional connectivity (intended as inter-regional synchronization), spectral and non-linear dynamical properties across cortical areas of the healthy human brain is considered. Based upon functional MRI acquisitions of spontaneous activity during wakeful idleness, node degree maps are determined by thresholding the temporal correlation coefficient among all voxel pairs. In addition, for individual voxel time-series, the relative amplitude of low-frequency fluctuations and the correlation dimension (D2), determined with respect to Fourier amplitude and value distribution matched surrogate data, are measured. Across cortical areas, high node degree is associated with a shift towards lower frequency activity and, compared to surrogate data, clearer saturation to a lower correlation dimension, suggesting presence of non-linear structure. An attempt to recapitulate this relationship in a network of single-transistor oscillators is made, based on a diffusive ring (n = 90) with added long-distance links defining four extended hub regions. Similarly to the brain data, it is found that oscillators in the hub regions generate signals with larger low-frequency cycle amplitude fluctuations and clearer saturation to a lower correlation dimension compared to surrogates. The effect emerges more markedly close to criticality. The homology observed between the two systems despite profound differences in scale, coupling mechanism and dynamics appears noteworthy. These experimental results motivate further investigation into the heterogeneity of cortical non-linear dynamics in relation to connectivity and underline the ability for small networks of single-transistor oscillators to recreate collective phenomena arising in much more complex biological systems, potentially representing a future platform for modelling disease-related changes. PMID:25833429

Improving the frequency precision of oscillators by synchronization.

PubMed

Cross, M C

2012-04-01

Improving the frequency precision by synchronizing a lattice of N oscillators with disparate frequencies is studied in the phase reduction limit. In the general case where the coupling is not purely dissipative the synchronized state consists of targetlike waves radiating from a local source, which is a region of higher-frequency oscillators. In this state the improvement of the frequency precision is shown to be independent of N for large N, but instead depends on the disorder and reflects the dependence of the frequency of the synchronized state on just those oscillators in the source region of the waves. These results are obtained by a mapping of the nonlinear phase dynamics onto the linear Anderson problem of the quantum mechanics of electrons on a random lattice in the tight-binding approximation.

Model based PI power system stabilizer design for damping low frequency oscillations in power systems.

PubMed

Salgotra, Aprajita; Pan, Somnath

2018-05-01

This paper explores a two-level control strategy by blending local controller with centralized controller for the low frequency oscillations in a power system. The proposed control scheme provides stabilization of local modes using a local controller and minimizes the effect of inter-connection of sub-systems performance through a centralized control. For designing the local controllers in the form of proportional-integral power system stabilizer (PI-PSS), a simple and straight forward frequency domain direct synthesis method is considered that works on use of a suitable reference model which is based on the desired requirements. Several examples both on one machine infinite bus and multi-machine systems taken from the literature are illustrated to show the efficacy of the proposed PI-PSS. The effective damping of the systems is found to be increased remarkably which is reflected in the time-responses; even unstable operation has been stabilized with improved damping after applying the proposed controller. The proposed controllers give remarkable improvement in damping the oscillations in all the illustrations considered here and as for example, the value of damping factor has been increased from 0.0217 to 0.666 in Example 1. The simulation results obtained by the proposed control strategy are favourably compared with some controllers prevalent in the literature. Copyright © 2018 ISA. Published by Elsevier Ltd. All rights reserved.

Atomic fountain clock with very high frequency stability employing a pulse-tube-cryocooled sapphire oscillator.

PubMed

Takamizawa, Akifumi; Yanagimachi, Shinya; Tanabe, Takehiko; Hagimoto, Ken; Hirano, Iku; Watabe, Ken-ichi; Ikegami, Takeshi; Hartnett, John G

2014-09-01

The frequency stability of an atomic fountain clock was significantly improved by employing an ultra-stable local oscillator and increasing the number of atoms detected after the Ramsey interrogation, resulting in a measured Allan deviation of 8.3 × 10(-14)τ(-1/2)). A cryogenic sapphire oscillator using an ultra-low-vibration pulse-tube cryocooler and cryostat, without the need for refilling with liquid helium, was applied as a local oscillator and a frequency reference. High atom number was achieved by the high power of the cooling laser beams and optical pumping to the Zeeman sublevel m(F) = 0 employed for a frequency measurement, although vapor-loaded optical molasses with the simple (001) configuration was used for the atomic fountain clock. The resulting stability is not limited by the Dick effect as it is when a BVA quartz oscillator is used as the local oscillator. The stability reached the quantum projection noise limit to within 11%. Using a combination of a cryocooled sapphire oscillator and techniques to enhance the atom number, the frequency stability of any atomic fountain clock, already established as primary frequency standard, may be improved without opening its vacuum chamber.

Stabilizing Effect of Sweep on Low-Frequency STBLI Unsteadiness

NASA Astrophysics Data System (ADS)

Adler, Michael; Gaitonde, Datta

2017-11-01

A Large-Eddy Simulation database is generated to examine unsteady shock/turbulent boundary-layer-interaction (STBLI) mechanisms in a Mach 2 swept-compression-corner. Such interactions exhibit open separation, with separation relief from the sweep, and lack the closed mean recirculation found in spanwise-homogeneous STBLIs. We find that the swept interaction lacks the low-frequency coherent shock unsteadiness, two-decades below incoming turbulent boundary layer scales, that is a principal feature of comparable closed separation STBLIs. Rather, the prominent unsteady content is a mid-frequency regime that develops in the separated shear layer and scales weakly with the local separation length. Additionally, a linear perturbation analysis of the unsteady flow indicates that the feedback pathway (associated with an absolute instability in spanwise-homogeneous interactions) is absent in swept-compression-corner interactions. This suggests that 1) the linear oscillator is an essential component of low-frequency unsteadiness in interactions with closed separation. 2) Low-frequency control efforts should be focused on disrupting this oscillator. 3) Introduction of 3D effects constitute one mechanism to disrupt the oscillator.

Low-Frequency Oscillations and Transport Processes Induced by Multiscale Transverse Structures in the Polar Wind Outflow: A Three-Dimensional Simulation

NASA Technical Reports Server (NTRS)

Ganguli, Supriya B.; Gavrishchaka, Valeriy V.

1999-01-01

Multiscale transverse structures in the magnetic-field-aligned flows have been frequently observed in the auroral region by FAST and Freja satellites. A number of multiscale processes, such as broadband low-frequency oscillations and various cross-field transport effects are well correlated with these structures. To study these effects, we have used our three-dimensional multifluid model with multiscale transverse inhomogeneities in the initial velocity profile. Self-consistent-frequency mode driven by local transverse gradients in the generation of the low field-aligned ion flow and associated transport processes were simulated. Effects of particle interaction with the self-consistent time-dependent three-dimensional wave potential have been modeled using a distribution of test particles. For typical polar wind conditions it has been found that even large-scale (approximately 50 - 100 km) transverse inhomogeneities in the flow can generate low-frequency oscillations that lead to significant flow modifications, cross-field particle diffusion, and other transport effects. It has also been shown that even small-amplitude (approximately 10 - 20%) short-scale (approximately 10 km) modulations of the original large-scale flow profile significantly increases low-frequency mode generation and associated cross-field transport, not only at the local spatial scales imposed by the modulations but also on global scales. Note that this wave-induced cross-field transport is not included in any of the global numerical models of the ionosphere, ionosphere-thermosphere, or ionosphere-polar wind. The simulation results indicate that the wave-induced cross-field transport not only affects the ion outflow rates but also leads to a significant broadening of particle phase-space distribution and transverse particle diffusion.

Data mining neocortical high-frequency oscillations in epilepsy and controls

PubMed Central

Stead, Matt; Krieger, Abba; Stacey, William; Maus, Douglas; Marsh, Eric; Viventi, Jonathan; Lee, Kendall H.; Marsh, Richard; Litt, Brian; Worrell, Gregory A.

2011-01-01

Transient high-frequency (100–500 Hz) oscillations of the local field potential have been studied extensively in human mesial temporal lobe. Previous studies report that both ripple (100–250 Hz) and fast ripple (250–500 Hz) oscillations are increased in the seizure-onset zone of patients with mesial temporal lobe epilepsy. Comparatively little is known, however, about their spatial distribution with respect to seizure-onset zone in neocortical epilepsy, or their prevalence in normal brain. We present a quantitative analysis of high-frequency oscillations and their rates of occurrence in a group of nine patients with neocortical epilepsy and two control patients with no history of seizures. Oscillations were automatically detected and classified using an unsupervised approach in a data set of unprecedented volume in epilepsy research, over 12 terabytes of continuous long-term micro- and macro-electrode intracranial recordings, without human preprocessing, enabling selection-bias-free estimates of oscillation rates. There are three main results: (i) a cluster of ripple frequency oscillations with median spectral centroid = 137 Hz is increased in the seizure-onset zone more frequently than a cluster of fast ripple frequency oscillations (median spectral centroid = 305 Hz); (ii) we found no difference in the rates of high frequency oscillations in control neocortex and the non-seizure-onset zone neocortex of patients with epilepsy, despite the possibility of different underlying mechanisms of generation; and (iii) while previous studies have demonstrated that oscillations recorded by parenchyma-penetrating micro-electrodes have higher peak 100–500 Hz frequencies than penetrating macro-electrodes, this was not found for the epipial electrodes used here to record from the neocortical surface. We conclude that the relative rate of ripple frequency oscillations is a potential biomarker for epileptic neocortex, but that larger prospective studies

Data mining neocortical high-frequency oscillations in epilepsy and controls.

PubMed

Blanco, Justin A; Stead, Matt; Krieger, Abba; Stacey, William; Maus, Douglas; Marsh, Eric; Viventi, Jonathan; Lee, Kendall H; Marsh, Richard; Litt, Brian; Worrell, Gregory A

2011-10-01

Transient high-frequency (100-500 Hz) oscillations of the local field potential have been studied extensively in human mesial temporal lobe. Previous studies report that both ripple (100-250 Hz) and fast ripple (250-500 Hz) oscillations are increased in the seizure-onset zone of patients with mesial temporal lobe epilepsy. Comparatively little is known, however, about their spatial distribution with respect to seizure-onset zone in neocortical epilepsy, or their prevalence in normal brain. We present a quantitative analysis of high-frequency oscillations and their rates of occurrence in a group of nine patients with neocortical epilepsy and two control patients with no history of seizures. Oscillations were automatically detected and classified using an unsupervised approach in a data set of unprecedented volume in epilepsy research, over 12 terabytes of continuous long-term micro- and macro-electrode intracranial recordings, without human preprocessing, enabling selection-bias-free estimates of oscillation rates. There are three main results: (i) a cluster of ripple frequency oscillations with median spectral centroid = 137 Hz is increased in the seizure-onset zone more frequently than a cluster of fast ripple frequency oscillations (median spectral centroid = 305 Hz); (ii) we found no difference in the rates of high frequency oscillations in control neocortex and the non-seizure-onset zone neocortex of patients with epilepsy, despite the possibility of different underlying mechanisms of generation; and (iii) while previous studies have demonstrated that oscillations recorded by parenchyma-penetrating micro-electrodes have higher peak 100-500 Hz frequencies than penetrating macro-electrodes, this was not found for the epipial electrodes used here to record from the neocortical surface. We conclude that the relative rate of ripple frequency oscillations is a potential biomarker for epileptic neocortex, but that larger prospective studies correlating high-frequency

Sustaining GHz oscillation of carbon nanotube based oscillators via a MHz frequency excitation

NASA Astrophysics Data System (ADS)

Motevalli, Benyamin; Taherifar, Neda; Zhe Liu, Jefferson

2016-05-01

There have been intensive studies to investigate the properties of gigahertz nano-oscillators based on multi-walled carbon nanotubes (MWCNTs). Many of these studies, however, revealed that the unique telescopic translational oscillations in such devices would damp quickly due to various energy dissipation mechanisms. This challenge remains the primary obstacle against its practical applications. Herein, we propose a design concept in which a GHz oscillation could be re-excited by a MHz mechanical motion. This design involves a triple-walled CNT, in which sliding of the longer inner tube at a MHz frequency can re-excite and sustain a GHz oscillation of the shorter middle tube. Our molecular dynamics (MD) simulations prove this design concept at ˜10 nm scale. A mathematical model is developed to explore the feasibility at a larger size scale. As an example, in an oscillatory system with the CNT’s length above 100 nm, the high oscillatory frequency range of 1.8-3.3 GHz could be excited by moving the inner tube at a much lower frequency of 53.4 MHz. This design concept together with the mechanical model could energize the development of GHz nano-oscillators in miniaturized electro-mechanical devices.

Analysis of high-frequency oscillations in mutually-coupled nano-lasers.

PubMed

Han, Hong; Shore, K Alan

2018-04-16

The dynamics of mutually coupled nano-lasers has been analyzed using rate equations which include the Purcell cavity-enhanced spontaneous emission factor F and the spontaneous emission coupling factor β. It is shown that in the mutually-coupled system, small-amplitude oscillations with frequencies of order 100 GHz are generated and are maintained with remarkable stability. The appearance of such high-frequency oscillations is associated with the effective reduction of the carrier lifetime for larger values of the Purcell factor, F, and spontaneous coupling factor, β. In mutually-coupled nano-lasers the oscillation frequency changes linearly with the frequency detuning between the lasers. For non-identical bias currents, the oscillation frequency of mutually-coupled nano-lasers also increases with bias current. The stability of the oscillations which appear in mutually coupled nano-lasers offers opportunities for their practical applications and notably in photonic integrated circuits.

Abnormal excitability and episodic low-frequency oscillations in the cerebral cortex of the tottering mouse.

PubMed

Cramer, Samuel W; Popa, Laurentiu S; Carter, Russell E; Chen, Gang; Ebner, Timothy J

2015-04-08

The Ca(2+) channelopathies caused by mutations of the CACNA1A gene that encodes the pore-forming subunit of the human Cav2.1 (P/Q-type) voltage-gated Ca(2+) channel include episodic ataxia type 2 (EA2). Although, in EA2 the emphasis has been on cerebellar dysfunction, patients also exhibit episodic, nonmotoric abnormalities involving the cerebral cortex. This study demonstrates episodic, low-frequency oscillations (LFOs) throughout the cerebral cortex of tottering (tg/tg) mice, a widely used model of EA2. Ranging between 0.035 and 0.11 Hz, the LFOs in tg/tg mice can spontaneously develop very high power, referred to as a high-power state. The LFOs in tg/tg mice are mediated in part by neuronal activity as tetrodotoxin decreases the oscillations and cortical neuron discharge contain the same low frequencies. The high-power state involves compensatory mechanisms because acutely decreasing P/Q-type Ca(2+) channel function in either wild-type (WT) or tg/tg mice does not induce the high-power state. In contrast, blocking l-type Ca(2+) channels, known to be upregulated in tg/tg mice, reduces the high-power state. Intriguingly, basal excitatory glutamatergic neurotransmission constrains the high-power state because blocking ionotropic or metabotropic glutamate receptors results in high-power LFOs in tg/tg but not WT mice. The high-power LFOs are decreased markedly by acetazolamide and 4-aminopyridine, the primary treatments for EA2, suggesting disease relevance. Together, these results demonstrate that the high-power LFOs in the tg/tg cerebral cortex represent a highly abnormal excitability state that may underlie noncerebellar symptoms that characterize CACNA1A mutations. Copyright © 2015 the authors 0270-6474/15/355664-16$15.00/0.

Low noise cryogenic dielectric resonator oscillator

NASA Technical Reports Server (NTRS)

Dick, G. John (Inventor)

1988-01-01

A microwave oscillator is provided which can operate at a temperature of many degrees above absolute zero while providing very low phase noise that has heretofore generally required temperatures within a few degrees K. The oscillator includes a ring-shaped resonant element of ruby (sapphire plus chromium) or iron sapphire crystal, lying adjacent to a resonator element of sapphire, so that the regenerator element lies directly in the magnetic field of the resonator element. The resonator element is substantially devoid of contact with electrically conductive material. Microwave energy of a pump frequency (e.g., 31 GHz) is outputted from the regenerator element, while signal energy (e.g., 10 GHz) is outputted from the resonator element.

Beat-to-Beat Variability of Ventricular Action Potential Duration Oscillates at Low Frequency During Sympathetic Provocation in Humans

PubMed Central

Porter, Bradley; van Duijvenboden, Stefan; Bishop, Martin J.; Orini, Michele; Claridge, Simon; Gould, Justin; Sieniewicz, Benjamin J.; Sidhu, Baldeep; Razavi, Reza; Rinaldi, Christopher A.; Gill, Jaswinder S.; Taggart, Peter

2018-01-01

Background: The temporal pattern of ventricular repolarization is of critical importance in arrhythmogenesis. Enhanced beat-to-beat variability (BBV) of ventricular action potential duration (APD) is pro-arrhythmic and is increased during sympathetic provocation. Since sympathetic nerve activity characteristically exhibits burst patterning in the low frequency range, we hypothesized that physiologically enhanced sympathetic activity may not only increase BBV of left ventricular APD but also impose a low frequency oscillation which further increases repolarization instability in humans. Methods and Results: Heart failure patients with cardiac resynchronization therapy defibrillator devices (n = 11) had activation recovery intervals (ARI, surrogate for APD) recorded from left ventricular epicardial electrodes alongside simultaneous non-invasive blood pressure and respiratory recordings. Fixed cycle length was achieved by right ventricular pacing. Recordings took place during resting conditions and following an autonomic stimulus (Valsalva). The variability of ARI and the normalized variability of ARI showed significant increases post Valsalva when compared to control (p = 0.019 and p = 0.032, respectively). The oscillatory behavior was quantified by spectral analysis. Significant increases in low frequency (LF) power (p = 0.002) and normalized LF power (p = 0.019) of ARI were seen following Valsalva. The Valsalva did not induce changes in conduction variability nor the LF oscillatory behavior of conduction. However, increases in the LF power of ARI were accompanied by increases in the LF power of systolic blood pressure (SBP) and the rate of systolic pressure increase (dP/dtmax). Positive correlations were found between LF-SBP and LF-dP/dtmax (rs = 0.933, p < 0.001), LF-ARI and LF-SBP (rs = 0.681, p = 0.001) and between LF-ARI and LF-dP/dtmax (rs = 0.623, p = 0.004). There was a strong positive correlation between the variability of ARI and LF power of ARI (rs = 0

Dependence of the colored frequency noise in spin torque oscillators on current and magnetic field

NASA Astrophysics Data System (ADS)

Eklund, Anders; Bonetti, Stefano; Sani, Sohrab R.; Majid Mohseni, S.; Persson, Johan; Chung, Sunjae; Amir Hossein Banuazizi, S.; Iacocca, Ezio; Östling, Mikael; Åkerman, Johan; Gunnar Malm, B.

2014-03-01

The nano-scale spin torque oscillator (STO) is a compelling device for on-chip, highly tunable microwave frequency signal generation. Currently, one of the most important challenges for the STO is to increase its longer-time frequency stability by decreasing the 1/f frequency noise, but its high level makes even its measurement impossible using the phase noise mode of spectrum analyzers. Here, we present a custom made time-domain measurement system with 150 MHz measurement bandwidth making possible the investigation of the variation of the 1/f as well as the white frequency noise in a STO over a large set of operating points covering 18-25 GHz. The 1/f level is found to be highly dependent on the oscillation amplitude-frequency non-linearity and the vicinity of unexcited oscillation modes. These findings elucidate the need for a quantitative theoretical treatment of the low-frequency, colored frequency noise in STOs. Based on the results, we suggest that the 1/f frequency noise possibly can be decreased by improving the microstructural quality of the metallic thin films.

Frequency stabilization in nonlinear MEMS and NEMS oscillators

DOEpatents

Lopez, Omar Daniel; Antonio, Dario

2014-09-16

An illustrative system includes an amplifier operably connected to a phase shifter. The amplifier is configured to amplify a voltage from an oscillator. The phase shifter is operably connected to a driving amplitude control, wherein the phase shifter is configured to phase shift the amplified voltage and is configured to set an amplitude of the phase shifted voltage. The oscillator is operably connected to the driving amplitude control. The phase shifted voltage drives the oscillator. The oscillator is at an internal resonance condition, based at least on the amplitude of the phase shifted voltage, that stabilizes frequency oscillations in the oscillator.

Coexistence of gamma and high-frequency oscillations in rat medial entorhinal cortex in vitro

PubMed Central

Cunningham, M O; Halliday, David M; Davies, Ceri H; Traub, Roger D; Buhl, Eberhard H; Whittington, Miles A

2004-01-01

High frequency oscillations (> 80–90 Hz) occur in neocortex and hippocampus in vivo where they are associated with specific behavioural states and more classical EEG frequency bands. In the hippocampus in vitro these oscillations can occur in the absence of pyramidal neuronal somatodendritic compartments and are temporally correlated with on-going, persistent gamma frequency oscillations. Their occurrence in the hippocampus is dependent on gap-junctional communication and it has been suggested that these high frequency oscillations originate as collective behaviour in populations of electrically coupled principal cell axonal compartments. Here we demonstrate that the superficial layers of medial entorhinal cortex can also generate high frequency oscillations associated with gamma rhythms. During persistent gamma frequency oscillations high frequency oscillations occur with a high bispectral coherence with the field gamma activity. Bursts of high frequency oscillations are temporally correlated with both the onset of compound excitatory postsynaptic potentials in fast-spiking interneurones and spikelet potentials in both pyramidal and stellate principal neurones. Both the gamma frequency and high frequency oscillations were attenuated by the gap junction blocker carbenoxolone. These data suggest that high frequency oscillations may represent the substrate for phasic drive to interneurones during persistent gamma oscillations in the medial entorhinal cortex. PMID:15254156

Synchronization, non-linear dynamics and low-frequency fluctuations: Analogy between spontaneous brain activity and networked single-transistor chaotic oscillators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Minati, Ludovico, E-mail: lminati@ieee.org, E-mail: ludovico.minati@unitn.it, E-mail: lminati@istituto-besta.it; Center for Mind/Brain Sciences, University of Trento, Trento; Chiesa, Pietro

In this paper, the topographical relationship between functional connectivity (intended as inter-regional synchronization), spectral and non-linear dynamical properties across cortical areas of the healthy human brain is considered. Based upon functional MRI acquisitions of spontaneous activity during wakeful idleness, node degree maps are determined by thresholding the temporal correlation coefficient among all voxel pairs. In addition, for individual voxel time-series, the relative amplitude of low-frequency fluctuations and the correlation dimension (D{sub 2}), determined with respect to Fourier amplitude and value distribution matched surrogate data, are measured. Across cortical areas, high node degree is associated with a shift towards lower frequencymore » activity and, compared to surrogate data, clearer saturation to a lower correlation dimension, suggesting presence of non-linear structure. An attempt to recapitulate this relationship in a network of single-transistor oscillators is made, based on a diffusive ring (n = 90) with added long-distance links defining four extended hub regions. Similarly to the brain data, it is found that oscillators in the hub regions generate signals with larger low-frequency cycle amplitude fluctuations and clearer saturation to a lower correlation dimension compared to surrogates. The effect emerges more markedly close to criticality. The homology observed between the two systems despite profound differences in scale, coupling mechanism and dynamics appears noteworthy. These experimental results motivate further investigation into the heterogeneity of cortical non-linear dynamics in relation to connectivity and underline the ability for small networks of single-transistor oscillators to recreate collective phenomena arising in much more complex biological systems, potentially representing a future platform for modelling disease-related changes.« less

Frequency-stabilization of mode-locked laser-based photonic microwave oscillator

NASA Technical Reports Server (NTRS)

Yu, Nan; Tu, Meirong; Salik, Ertan; Maleki, Lute

2005-01-01

In this paper, we will describe our recent phase-noise measurements of photonic microwave oscillators. We will aslo discuss our investigation of the frequency stability link between the optical and microwave frequencies in the coupled oscillator.

Modulation linearization of a frequency-modulated voltage controlled oscillator, part 3

NASA Technical Reports Server (NTRS)

Honnell, M. A.

1975-01-01

An analysis is presented for the voltage versus frequency characteristics of a varactor modulated VHF voltage controlled oscillator in which the frequency deviation is linearized by using the nonlinear characteristics of a field effect transistor as a signal amplifier. The equations developed are used to calculate the oscillator output frequency in terms of pertinent circuit parameters. It is shown that the nonlinearity exponent of the FET has a pronounced influence on frequency deviation linearity, whereas the junction exponent of the varactor controls total frequency deviation for a given input signal. A design example for a 250 MHz frequency modulated oscillator is presented.

A Sub-Hertz, Low-Frequency Vibration Isolation Platform

NASA Technical Reports Server (NTRS)

Ortiz, Gerardo, G.; Farr, William H.; Sannibale, Virginio

2011-01-01

One of the major technical problems deep-space optical communication (DSOC) systems need to solve is the isolation of the optical terminal from vibrations produced by the spacecraft navigational control system and by the moving parts of onboard instruments. Even under these vibration perturbations, the DSOC transceivers (telescopes) need to be pointed l000 fs of times more accurately than an RF communication system (parabolic antennas). Mechanical resonators have been extensively used to provide vibration isolation for groundbased, airborne, and spaceborne payloads. The effectiveness of these isolation systems is determined mainly by the ability of designing a mechanical oscillator with the lowest possible resonant frequency. The Low-Frequency Vibration Isolation Platform (LFVIP), developed during this effort, aims to reduce the resonant frequency of the mechanical oscillators into the sub-Hertz region in order to maximize the passive isolation afforded by the 40 dB/decade roll-off response of the resonator. The LFVIP also provides tip/tilt functionality for acquisition and tracking of a beacon signal. An active control system is used for platform positioning and for dampening of the mechanical oscillator. The basic idea in the design of the isolation platform is to use a passive isolation strut with an approximately equal to 100-mHz resonance frequency. This will extend the isolation range to lower frequencies. The harmonic oscillator is a second-order lowpass filter for mechanical disturbances. The resonance quality depends on the dissipation mechanisms, which are mainly hysteretic because of the low resonant frequency and the absence of any viscous medium. The LFVIP system is configured using the well-established Stewart Platform, which consists of a top platform connected to a base with six extensible struts (see figure). The struts are attached to the base and to the platform via universal joints, which permit the extension and contraction of the struts. The

High frequency inductive lamp and power oscillator

DOEpatents

MacLennan, Donald A.; Dymond, Jr., Lauren E.; Gitsevich, Aleksandr; Grimm, William G.; Kipling, Kent; Kirkpatrick, Douglas A.; Ola, Samuel A.; Simpson, James E.; Trimble, William C.; Tsai, Peter; Turner, Brian P.

2001-01-01

A high frequency inductively coupled electrodeless lamp includes an excitation coil with an effective electrical length which is less than one half wavelength of a driving frequency applied thereto, preferably much less. The driving frequency may be greater than 100 MHz and is preferably as high as 915 MHz. Preferably, the excitation coil is configured as a non-helical, semi-cylindrical conductive surface having less than one turn, in the general shape of a wedding ring. At high frequencies, the current in the coil forms two loops which are spaced apart and parallel to each other. Configured appropriately, the coil approximates a Helmholtz configuration. The lamp preferably utilizes an bulb encased in a reflective ceramic cup with a pre-formed aperture defined therethrough. The ceramic cup may include structural features to aid in alignment and I or a flanged face to aid in thermal management. The lamp head is preferably an integrated lamp head comprising a metal matrix composite surrounding an insulating ceramic with the excitation integrally formed on the ceramic. A novel solid-state oscillator preferably provides RF power to the lamp. The oscillator is a single active element device capable of providing over 70 watts of power at over 70% efficiency. Various control circuits may be employed to adjust the driving frequency of the oscillator.

High frequency inductive lamp and power oscillator

DOEpatents

MacLennan, Donald A.; Turner, Brian P.; Dolan, James T.; Kirkpatrick, Douglas A.; Leng, Yongzhang

2000-01-01

A high frequency inductively coupled electrodeless lamp includes an excitation coil with an effective electrical length which is less than one half wavelength of a driving frequency applied thereto, preferably much less. The driving frequency may be greater than 100 MHz and is preferably as high as 915 MHz. Preferably, the excitation coil is configured as a non-helical, semi-cylindrical conductive surface having less than one turn, in the general shape of a wedding ring. At high frequencies, the current in the coil forms two loops which are spaced apart and parallel to each other. Configured appropriately, the coil approximates a Helmholtz configuration. The lamp preferably utilizes an bulb encased in a reflective ceramic cup with a pre-formed aperture defined therethrough. The ceramic cup may include structural features to aid in alignment and/or a flanged face to aid in thermal management. The lamp head is preferably an integrated lamp head comprising a metal matrix composite surrounding an insulating ceramic with the excitation integrally formed on the ceramic. A novel solid-state oscillator preferably provides RF power to the lamp. The oscillator is a single active element device capable of providing over 70 watts of power at over 70% efficiency. Various control circuits may be employed to match the driving frequency of the oscillator to a plurality of tuning states of the lamp.

He's Frequency Formulation for Nonlinear Oscillators

ERIC Educational Resources Information Center

Geng, Lei; Cai, Xu-Chu

2007-01-01

Based on an ancient Chinese algorithm, J H He suggested a simple but effective method to find the frequency of a nonlinear oscillator. In this paper, a modified version is suggested to improve the accuracy of the frequency; two examples are given, revealing that the obtained solutions are of remarkable accuracy and are valid for the whole solution…

Somatic evoked high-frequency magnetic oscillations reflect activity of inhibitory interneurons in the human somatosensory cortex.

PubMed

Hashimoto, I; Mashiko, T; Imada, T

1996-05-01

High-frequency potential oscillations in the range of 300-900 Hz have recently been shown to concur with the primary response (N20) of the somatosensory cortex in awake humans. However, the physiological mechanisms of the high-frequency oscillations remained undetermined. We addressed the issue by analyzing magnetic fields during wakefulness and sleep over the left hemisphere to right median nerve stimulation with a wide bandpass (0.1-2000 Hz) recording with subsequent high-pass (> 300 Hz) and low-pass (< 300 Hz) filtering. With wide bandpass recordings, high-frequency magnetic oscillations with the main signal energy at 580-780 Hz were superimposed on the N20m during wakefulness. Isofield mapping at each peak of the high-pass filtered and isolated high-frequency oscillations showed a dipolar pattern and the estimated source for these peaks was the primary somatosensory cortex (area 3b) very close to that for the N20m peak. During sleep, the high-frequency oscillations showed dramatic diminution in amplitude while the N20m amplitude exhibited a moderate increment. This reciprocal relation between the high-frequency oscillations and the N20m during a wake-sleep cycle suggests that they represent different generator substrates. We speculate that the high-frequency oscillations represent a localized activity of the GABAergic inhibitory interneurons of layer 4, which have been shown in animal experiments to respond monosynaptically to thalamo-cortical input with a high-frequency (600-900 Hz) burst of short duration spikes. On the other hand, the underlying N20m represents activity of pyramidal neurons which receive monosynaptic excitatory input from the thalamus as well as a feed-forward inhibition from the interneurons.

Low Noise Frequency Comb Sources Based on Synchronously Pumped Doubly Resonant Optical Parametric Oscillators

NASA Astrophysics Data System (ADS)

Wan, Chenchen

Optical frequency combs are coherent light sources consist of thousands of equally spaced frequency lines. Frequency combs have achieved success in applications of metrology, spectroscopy and precise pulse manipulation and control. The most common way to generate frequency combs is based on mode-locked lasers which has the output spectrum of comb structures. To generate stable frequency combs, the output from mode-locked lasers need to be phase stabilized. The whole comb lines will be stabilized if the pulse train repetition rate corresponding to comb spacing and the pulse carrier envelope offset (CEO) frequency are both stabilized. The output from a laser always has fluctuations in parameters known as noise. In laser applications, noise is an important factor to limit the performance and often need to be well controlled. For example in precision measurement such as frequency metrology and precise spectroscopy, low laser intensity and phase noise is required. In mode-locked lasers there are different types of noise like intensity noise, pulse temporal position noise also known as timing jitter, optical phase noise. In term for frequency combs, these noise dynamics is more complex and often related. Understanding the noise behavior is not only of great interest in practical applications but also help understand fundamental laser physics. In this dissertation, the noise of frequency combs and mode-locked lasers will be studied in two projects. First, the CEO frequency phase noise of a synchronously pumped doubly resonant optical parametric oscillators (OPO) will be explored. This is very important for applications of the OPO as a coherent frequency comb source. Another project will focus on the intensity noise coupling in a soliton fiber oscillator, the finding of different noise coupling in soliton pulses and the dispersive waves generated from soliton perturbation can provide very practical guidance for low noise soliton laser design. OPOs are used to generate

Beta-gamma burst stimulations of the inferior olive induce high-frequency oscillations in the deep cerebellar nuclei.

PubMed

Cheron, Julian; Cheron, Guy

2018-02-20

The cerebellum displays various sorts of rhythmic activities covering both low- and high-frequency oscillations. These cerebellar high-frequency oscillations were observed in the cerebellar cortex. Here, we hypothesised that not only is the cerebellar cortex a generator of high-frequency oscillations but also that the deep cerebellar nuclei may also play a similar role. Thus, we analysed local field potentials and single-unit activities in the deep cerebellar nuclei before, during and after electric stimulation in the inferior olive of awake mice. A high-frequency oscillation of 350 Hz triggered by the stimulation of the inferior olive, within the beta-gamma range, was observed in the deep cerebellar nuclei. The amplitude and frequency of the oscillation were independent of the frequency of stimulation. This oscillation emerged during the period of stimulation and persisted after the end of the stimulation. The oscillation coincided with the inhibition of deep cerebellar neurons. As the inhibition of the deep cerebellar nuclei is related to inhibitory inputs from Purkinje cells, we speculate that the oscillation represents the unmasking of the synchronous activation of another subtype of deep cerebellar neuronal subtype, devoid of GABA receptors and under the direct control of the climbing fibres from the inferior olive. Still, the mechanism sustaining this oscillation remains to be deciphered. Our study sheds new light on the role of the olivo-cerebellar loop as the final output control of the intercerebellar circuitry. © 2018 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.

Stabilizing Microwave Frequency of a Photonic Oscillator

NASA Technical Reports Server (NTRS)

Maleki, Lute; Yu, Nan; Tu, Meirong

2006-01-01

A scheme for stabilizing the frequency of a microwave signal is proposed that exploits the operational characteristics of a coupled optoelectronic oscillator (COEO) and related optoelectronic equipment. An essential element in the scheme is a fiber mode-locked laser (MLL), the optical frequency of which is locked to an atomic transition. In this scheme, the optical frequency stability of the mode-locked laser is transferred to that of the microwave in the same device. Relative to prior schemes for using wideband optical frequency comb to stabilize microwave signals, this scheme is simpler and lends itself more readily to implementation in relatively compact, rugged equipment. The anticipated development of small, low-power, lightweight, highly stable microwave oscillators based on this scheme would afford great benefits in communication, navigation, metrology, and fundamental sciences. COEOs of various designs, at various stages of development, in some cases called by different names, have been described in a number of prior NASA Tech Briefs articles. A COEO is an optoelectronic apparatus that generates both short (picosecond) optical pulses and a steady microwave signal having an ultrahigh degree of spectral purity. The term "coupled optoelectronic" in the full name of such an apparatus signifies that its optical and electronic oscillations are coupled to each other in a single device. The present frequency-stabilization scheme is best described indirectly by describing the laboratory apparatus used to demonstrate it. The apparatus (see figure) includes a COEO that generates a comb-like optical spectrum, the various frequency components of which interfere, producing short optical pulses. This spectrum is centered at a nominal wavelength of 1,560 nm. The spectrum separation of this comb is about 10 GHz, as determined primarily by the length of an optical loop and the bandpass filter in the microwave feedback loop. The optical loop serves as microwave resonator

Trapped Ion Oscillation Frequencies as Sensors for Spectroscopy

PubMed Central

Vogel, Manuel; Quint, Wolfgang; Nörtershäuser, Wilfried

2010-01-01

The oscillation frequencies of charged particles in a Penning trap can serve as sensors for spectroscopy when additional field components are introduced to the magnetic and electric fields used for confinement. The presence of so-called “magnetic bottles” and specific electric anharmonicities creates calculable energy-dependences of the oscillation frequencies in the radiofrequency domain which may be used to detect the absorption or emission of photons both in the microwave and optical frequency domains. The precise electronic measurement of these oscillation frequencies therefore represents an optical sensor for spectroscopy. We discuss possible applications for precision laser and microwave spectroscopy and their role in the determination of magnetic moments and excited state life-times. Also, the trap-assisted measurement of radiative nuclear de-excitations in the X-ray domain is discussed. This way, the different applications range over more than 12 orders of magnitude in the detectable photon energies, from below μeV in the microwave domain to beyond MeV in the X-ray domain. PMID:22294921

Low-frequency oscillation amplitude elevation of prefrontal cerebral hemodynamics with driving duration during prolonged driving test

NASA Astrophysics Data System (ADS)

Deng, Zishan; Gao, Yuan; Li, Ting

2018-02-01

It has been observed that there is a low-frequency oscillation (LFO) around 0.1 Hz in cerebral hemodynamics related to brain activity. Since functional near-infrared spectroscopy (fNIRS) is a novel technique to monitor hemodynamic responses noninvasively, we applied it to detect LFOs of cerebral hemodynamic parameters, such as oxyhemoglobin and deoxyhemoglobin, during prolonged driving. We performed an experiment lasting for 7 hours and an experimental test was done every hour and 8 times altogether. 7 subjects were recruited and the data of 3 of them were analyzed. By means of Fourier transformation, the amplitude of the three parameters during each test at 0.1 Hz in frequency domain was extracted. The results showed an increasing trend in the 0.1 Hz amplitudes of the three hemodynamic parameters during 7 hours' simulated driving test. Our findings indicated the potential of LFOs of prefrontal cerebral hemodynamics in brain research and brain function evaluation.

Sustainable limitation of high-frequency oscillations of elevator cabin

NASA Astrophysics Data System (ADS)

Kaytukov, Batraz

2017-10-01

In this paper, a problem of sustainable limitation of vertical high-frequency oscillations of elevator cabin in buildings with various number of storeys is considered. To solve this problem, dynamic model of the elevator movement was developed. In the course of analytical and experimental studies, the main cause for emergence of undesirable high-frequency oscillations of a cabin was defined. The amplification factor which is the function of λ and length of cable was determined. The λ parameter is variable, and length of the cable changes depending on length passed by the cabin and is an amplification factor argument. For sustainable limitation of oscillations, use of dynamic dumper of lever type is proposed. Adjustment of the dumper natural vibration frequency in such a way that it is equal to the excitation frequency allows limiting of oscillations of the cabin and the elevator machine to reasonable value irrespective to position of a moving cabin in the shaft. Using dependences and plots which were obtained in the course of scientific analysis and experimental studies, reasonability of dumper application for sustainable limitation of high-frequency influence of the elevator machine on the base and obtaining of solutions of inertial forces equilibration problem was proved.

Comparing performance of three oscillating positive expiratory pressure devices at similar amplitude and frequencies of oscillations on displacement of mucus inside trachea during cough.

PubMed

Ragavan, Anpalaki J

2012-03-13

Performance of Flutter® (Axcan Scandipharm Inc, Birmingham, AL), Acapella® (Smiths Medicals Inc, Rockland, MA) and Quake® (Thayer Medical, Tucson, AZ) were compared at similar frequencies and amplitudes of oscillations at nine angles of the device in clearing simulated mucus inside a tracheal model (trachea) oriented at three angles with or without simulated constrictions in airway upstream of trachea. Displacement of 0.4mL of simulated mucus prepared with viscoelastic properties similar to healthy individuals (syrup-like) or patients with COPD (gel-like) using locust bean gum(LBG) solution (0.38g LBG in 100mL water) cross-linked with 3mL or 12mL borax solution (0.02 molar), respectively were measured inside trachea during coughs of 300ms at low cough velocity (15±0.5m/s) generated using a computer controlled solenoid valve. Oscillations were superimposed on cough by connecting the oscillator device to the outlet of the trachea. Frequency and amplitude of oscillations generated by Quake and Acapella and resulting mucus displacement were independent of angle of oscillator, while amplitude of oscillations and resulting mucus displacement generated by Flutter, increased up to 30o upward and 20o downward angles of Flutter from horizontal but decreased significantly thereafter. Displacement with Quake increased significantly with frequencies of oscillations up to 25 Hz and decreased thereafter but increased with amplitudes of oscillations up to 22±4.7 m/s. Quake showed significantly larger displacements than Flutter and Acapella at equal frequencies and amplitudes (p<0.05). Displacements were significantly larger with trachea positioned 30o upwards than horizontal or 20o downwards (p<0.0001). Displacement was the greatest for gel-like mucus than syrup-like (p<0.0001). Airway constrictions upstream resulted in enhanced displacement of mucus (p<0.0001). Mucus clearance can be significantly enhanced by coughing through oscillating positive expiratory devices that

Frequency control of a spin-torque oscillator using magnetostrictive anisotropy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Park, Min Gyu Albert; Lee, Seok-Hee, E-mail: bgpark@kaist.ac.kr, E-mail: shlee@kaist.edu; Baek, Seung-heon Chris

2016-01-11

We report the working principle of a spin-torque oscillator, of which the frequency is efficiently controlled by manipulating the magnetostrictive anisotropy. To justify the scheme, we simulate a conventional magnetic-tunnel junction-based oscillator which is fabricated on a piezoelectric material. By applying mechanical stress to a free layer using a piezoelectric material, the oscillation frequency can be controlled to ensure a broad tuning range without a significant reduction of the dynamic resistance variation. Such controllability, which appears in the absence of an external magnetic field, will not only enable the integration of spin-torque oscillators and conventional complimentary metal-oxide semiconductor technology butmore » will also broaden the applicability of spin-torque oscillators.« less

Observation of beat oscillation generation by coupled waves associated with parametric decay during radio frequency wave heating of a spherical tokamak plasma.

PubMed

Nagashima, Yoshihiko; Oosako, Takuya; Takase, Yuichi; Ejiri, Akira; Watanabe, Osamu; Kobayashi, Hiroaki; Adachi, Yuuki; Tojo, Hiroshi; Yamaguchi, Takashi; Kurashina, Hiroki; Yamada, Kotaro; An, Byung Il; Kasahara, Hiroshi; Shimpo, Fujio; Kumazawa, Ryuhei; Hayashi, Hiroyuki; Matsuzawa, Haduki; Hiratsuka, Junichi; Hanashima, Kentaro; Kakuda, Hidetoshi; Sakamoto, Takuya; Wakatsuki, Takuma

2010-06-18

We present an observation of beat oscillation generation by coupled modes associated with parametric decay instability (PDI) during radio frequency (rf) wave heating experiments on the Tokyo Spherical Tokamak-2. Nearly identical PDI spectra, which are characterized by the coexistence of the rf pump wave, the lower-sideband wave, and the low-frequency oscillation in the ion-cyclotron range of frequency, are observed at various locations in the edge plasma. A bispectral power analysis was used to experimentally discriminate beat oscillation from the resonant mode for the first time. The pump and lower-sideband waves have resonant mode components, while the low-frequency oscillation is exclusively excited by nonlinear coupling of the pump and lower-sideband waves. Newly discovered nonlocal transport channels in spectral space and in real space via PDI are described.

Cross-frequency coupling of brain oscillations in studying motivation and emotion.

PubMed

Schutter, Dennis J L G; Knyazev, Gennady G

2012-03-01

Research has shown that brain functions are realized by simultaneous oscillations in various frequency bands. In addition to examining oscillations in pre-specified bands, interactions and relations between the different frequency bandwidths is another important aspect that needs to be considered in unraveling the workings of the human brain and its functions. In this review we provide evidence that studying interdependencies between brain oscillations may be a valuable approach to study the electrophysiological processes associated with motivation and emotional states. Studies will be presented showing that amplitude-amplitude coupling between delta-alpha and delta-beta oscillations varies as a function of state anxiety and approach-avoidance-related motivation, and that changes in the association between delta-beta oscillations can be observed following successful psychotherapy. Together these studies suggest that cross-frequency coupling of brain oscillations may contribute to expanding our understanding of the neural processes underlying motivation and emotion.

Coordinated infraslow neural and cardiac oscillations mark fragility and offline periods in mammalian sleep

PubMed Central

Lecci, Sandro; Fernandez, Laura M. J.; Weber, Frederik D.; Cardis, Romain; Chatton, Jean-Yves; Born, Jan; Lüthi, Anita

2017-01-01

Rodents sleep in bouts lasting minutes; humans sleep for hours. What are the universal needs served by sleep given such variability? In sleeping mice and humans, through monitoring neural and cardiac activity (combined with assessment of arousability and overnight memory consolidation, respectively), we find a previously unrecognized hallmark of sleep that balances two fundamental yet opposing needs: to maintain sensory reactivity to the environment while promoting recovery and memory consolidation. Coordinated 0.02-Hz oscillations of the sleep spindle band, hippocampal ripple activity, and heart rate sequentially divide non–rapid eye movement (non-REM) sleep into offline phases and phases of high susceptibility to external stimulation. A noise stimulus chosen such that sleeping mice woke up or slept through at comparable rates revealed that offline periods correspond to raising, whereas fragility periods correspond to declining portions of the 0.02-Hz oscillation in spindle activity. Oscillations were present throughout non-REM sleep in mice, yet confined to light non-REM sleep (stage 2) in humans. In both species, the 0.02-Hz oscillation predominated over posterior cortex. The strength of the 0.02-Hz oscillation predicted superior memory recall after sleep in a declarative memory task in humans. These oscillations point to a conserved function of mammalian non-REM sleep that cycles between environmental alertness and internal memory processing in 20- to 25-s intervals. Perturbed 0.02-Hz oscillations may cause memory impairment and ill-timed arousals in sleep disorders. PMID:28246641

Evidence for an Optical Low-frequency Quasi-periodic Oscillation in the Kepler Light Curve of an Active Galaxy

NASA Astrophysics Data System (ADS)

Smith, Krista Lynne; Mushotzky, Richard F.; Boyd, Patricia T.; Wagoner, Robert V.

2018-06-01

We report evidence for a quasi-periodic oscillation (QPO) in the optical light curve of KIC 9650712, a narrow-line Seyfert 1 galaxy in the original Kepler field. After the development and application of a pipeline for Kepler data specific to active galactic nuclei (AGNs), one of our sample of 21 AGNs selected by infrared photometry and X-ray flux demonstrates a peak in the power spectrum at log ν = ‑6.58 Hz, corresponding to a temporal period of t = 44 days. We note that although the power spectrum is well fit by a model consisting of a Lorentzian and a single power law, alternative continuum models cannot be ruled out. From optical spectroscopy, we measure the black hole mass of this AGN as log (M BH/M ⊙) = 8.17. We find that this frequency lies along a correlation between low-frequency QPOs and black hole mass from stellar and intermediate mass black holes to AGNs, similar to the known correlation in high-frequency QPOs.

Acetylcholine modulates gamma frequency oscillations in the hippocampus by activation of muscarinic M1 receptors.

PubMed

Betterton, Ruth T; Broad, Lisa M; Tsaneva-Atanasova, Krasimira; Mellor, Jack R

2017-06-01

Modulation of gamma oscillations is important for the processing of information and the disruption of gamma oscillations is a prominent feature of schizophrenia and Alzheimer's disease. Gamma oscillations are generated by the interaction of excitatory and inhibitory neurons where their precise frequency and amplitude are controlled by the balance of excitation and inhibition. Acetylcholine enhances the intrinsic excitability of pyramidal neurons and suppresses both excitatory and inhibitory synaptic transmission, but the net modulatory effect on gamma oscillations is not known. Here, we find that the power, but not frequency, of optogenetically induced gamma oscillations in the CA3 region of mouse hippocampal slices is enhanced by low concentrations of the broad-spectrum cholinergic agonist carbachol but reduced at higher concentrations. This bidirectional modulation of gamma oscillations is replicated within a mathematical model by neuronal depolarisation, but not by reducing synaptic conductances, mimicking the effects of muscarinic M1 receptor activation. The predicted role for M1 receptors was supported experimentally; bidirectional modulation of gamma oscillations by acetylcholine was replicated by a selective M1 receptor agonist and prevented by genetic deletion of M1 receptors. These results reveal that acetylcholine release in CA3 of the hippocampus modulates gamma oscillation power but not frequency in a bidirectional and dose-dependent manner by acting primarily through muscarinic M1 receptors. © 2017 The Authors. European Journal of Neuroscience published by Federation of European Neuroscience Societies and John Wiley & Sons Ltd.

Synchronization of electrically coupled micromechanical oscillators with a frequency ratio of 3:1

NASA Astrophysics Data System (ADS)

Pu, Dong; Wei, Xueyong; Xu, Liu; Jiang, Zhuangde; Huan, Ronghua

2018-01-01

In this Letter, synchronization of micromechanical oscillators with a frequency ratio of 3:1 is reported. Two electrically coupled piezoresistive micromechanical oscillators are built for the study, and their oscillation frequencies are tuned via the Joule heating effect to find out the synchronization region. Experimental results show that the larger coupling strength or bias driving voltage is applied and a wider synchronization region is obtained. Interestingly, however, the oscillator's frequency tunability is dramatically reduced from -809.1 Hz/V to -23.1 Hz/V when synchronization is reached. A nearly 10-fold improvement of frequency stability at 1 s is observed from one of the synchronized oscillators, showing a comparable performance of the other. The stable high order synchronization of micromechanical oscillators is helpful to design high performance resonant sensors with a better frequency resolution and a larger scale factor.

Dominant side in single-leg stance stability during floor oscillations at various frequencies

PubMed Central

2014-01-01

Background We investigated lateral dominance in the postural stability of single-leg stance with anteroposterior floor oscillations at various frequencies. Methods Thirty adults maintained a single-leg stance on a force platform for 20 seconds per trial. Trials were performed with no oscillation (static condition) and with anteroposterior floor oscillations (2.5-cm amplitude) at six frequencies: 0.25, 0.5, 0.75, 1.0, 1.25 and 1.5 Hz (dynamic condition). A set of three trials was performed on each leg in each oscillation frequency in random order. The mean speed of the center of pressure in the anteroposterior direction (CoPap) was calculated as an index of postural stability, and frequency analysis of CoPap sway was performed. Footedness for carrying out mobilizing activities was assessed with a questionnaire. Results CoPap speed exponentially increased as oscillation frequency increased in both legs. The frequency analysis of CoPap showed a peak <0.3 Hz at no oscillation. The frequency components at 0.25-Hz oscillation included common components with no oscillation and those at 1.5-Hz oscillation showed the maximum amplitude among all conditions. Postural stability showed no significant difference between left- and right-leg stance at no oscillation and oscillations ≤1.25 Hz, but at 1.5-Hz oscillation was significantly higher in the right-leg stance than in the left-leg stance. For the lateral dominance of postural stability at individual levels, the lateral difference in postural stability at no oscillation was positively correlated with that at 0.25-Hz oscillation (r = 0.51) and negatively correlated with that at 1.5-Hz oscillation (r = -0.53). For 70% of subjects, the dominant side of postural stability was different at no oscillation and 1.5-Hz oscillation. In the subjects with left- or right-side dominance at no oscillation, 94% or 38% changed their dominant side at 1.5-Hz oscillation, with a significant difference between these percentages. In

Effects of dendritic load on the firing frequency of oscillating neurons.

PubMed

Schwemmer, Michael A; Lewis, Timothy J

2011-03-01

We study the effects of passive dendritic properties on the dynamics of neuronal oscillators. We find that the addition of a passive dendrite can sometimes have counterintuitive effects on firing frequency. Specifically, the addition of a hyperpolarized passive dendritic load can either increase, decrease, or have negligible effects on firing frequency. We use the theory of weak coupling to derive phase equations for "ball-and-stick" model neurons and two-compartment model neurons. We then develop a framework for understanding how the addition of passive dendrites modulates the frequency of neuronal oscillators. We show that the average value of the neuronal oscillator's phase response curves measures the sensitivity of the neuron's firing rate to the dendritic load, including whether the addition of the dendrite causes an increase or decrease in firing frequency. We interpret this finding in terms of to the slope of the neuronal oscillator's frequency-applied current curve. We also show that equivalent results exist for constant and noisy point-source input to the dendrite. We note that the results are not specific to neurons but are applicable to any oscillator subject to a passive load.

Frequency modulation of neural oscillations according to visual task demands.

PubMed

Wutz, Andreas; Melcher, David; Samaha, Jason

2018-02-06

Temporal integration in visual perception is thought to occur within cycles of occipital alpha-band (8-12 Hz) oscillations. Successive stimuli may be integrated when they fall within the same alpha cycle and segregated for different alpha cycles. Consequently, the speed of alpha oscillations correlates with the temporal resolution of perception, such that lower alpha frequencies provide longer time windows for perceptual integration and higher alpha frequencies correspond to faster sampling and segregation. Can the brain's rhythmic activity be dynamically controlled to adjust its processing speed according to different visual task demands? We recorded magnetoencephalography (MEG) while participants switched between task instructions for temporal integration and segregation, holding stimuli and task difficulty constant. We found that the peak frequency of alpha oscillations decreased when visual task demands required temporal integration compared with segregation. Alpha frequency was strategically modulated immediately before and during stimulus processing, suggesting a preparatory top-down source of modulation. Its neural generators were located in occipital and inferotemporal cortex. The frequency modulation was specific to alpha oscillations and did not occur in the delta (1-3 Hz), theta (3-7 Hz), beta (15-30 Hz), or gamma (30-50 Hz) frequency range. These results show that alpha frequency is under top-down control to increase or decrease the temporal resolution of visual perception.

A Resonantly Excited Disk-Oscillation Model of High-Frequency QPOs of Microquasars

NASA Astrophysics Data System (ADS)

Kato, Shoji

2012-12-01

A possible model of twin high-frequency QPOs (HF QPOs) of microquasars is examined. The disk is assumed to have global magnetic fields and to be deformed with a two-armed pattern. In this deformed disk, a set of a two-armed (m = 2) vertical p-mode oscillation and an axisymmetric (m = 0) g-mode oscillation is considered. They resonantly interact through the disk deformation when their frequencies are the same. This resonant interaction amplifies the set of the above oscillations in the case where these two oscillations have wave energies of opposite signs. These oscillations are assumed to be excited most efficiently in the case where the radial group velocities of these two waves vanish at the same place. The above set of oscillations is not unique, depending on the node number n, of oscillations in the vertical direction. We consider that the basic two sets of oscillations correspond to the twin QPOs. The frequencies of these oscillations depend on the disk parameters, such as the strength of the magnetic fields. For observational mass ranges of GRS 1915+ 105, GRO J1655-40, XTE J1550-564, and HEAO H1743-322, the spins of these sources are estimated. High spins of these sources can be described if the disks have weak poloidal magnetic fields as well as toroidal magnetic fields of moderate strength. In this model the 3:2 frequency ratio of high-frequency QPOs is not related to their excitation, but occurs by chance.

Oscillator or Amplifier With Wide Frequency Range

NASA Technical Reports Server (NTRS)

Kleinberg, L.; Sutton, J.

1987-01-01

Inductive and capacitive effects synthesized with feedback circuits. Oscillator/amplifier resistively tunable over wide frequency range. Feedback circuits containing operational amplifiers, resistors, and capacitors synthesize electrical effects of inductance and capacitance in parallel between input terminals. Synthetic inductance and capacitance, and, therefore, resonant frequency of input admittance, adjusted by changing potentiometer setting.

Transient visual responses reset the phase of low-frequency oscillations in the skeletomotor periphery.

PubMed

Wood, Daniel K; Gu, Chao; Corneil, Brian D; Gribble, Paul L; Goodale, Melvyn A

2015-08-01

We recorded muscle activity from an upper limb muscle while human subjects reached towards peripheral targets. We tested the hypothesis that the transient visual response sweeps not only through the central nervous system, but also through the peripheral nervous system. Like the transient visual response in the central nervous system, stimulus-locked muscle responses (< 100 ms) were sensitive to stimulus contrast, and were temporally and spatially dissociable from voluntary orienting activity. Also, the arrival of visual responses reduced the variability of muscle activity by resetting the phase of ongoing low-frequency oscillations. This latter finding critically extends the emerging evidence that the feedforward visual sweep reduces neural variability via phase resetting. We conclude that, when sensory information is relevant to a particular effector, detailed information about the sensorimotor transformation, even from the earliest stages, is found in the peripheral nervous system. © 2015 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.

Graphene-hexagonal boron nitride resonant tunneling diodes as high-frequency oscillators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gaskell, J.; Fromhold, T. M.; Greenaway, M. T.

We assess the potential of two-terminal graphene-hexagonal boron nitride-graphene resonant tunneling diodes as high-frequency oscillators, using self-consistent quantum transport and electrostatic simulations to determine the time-dependent response of the diodes in a resonant circuit. We quantify how the frequency and power of the current oscillations depend on the diode and circuit parameters including the doping of the graphene electrodes, device geometry, alignment of the graphene lattices, and the circuit impedances. Our results indicate that current oscillations with frequencies of up to several hundred GHz should be achievable.

Evolutionary Model and Oscillation Frequencies for α Ursae Majoris: A Comparison with Observations

NASA Astrophysics Data System (ADS)

Guenther, D. B.; Demarque, P.; Buzasi, D.; Catanzarite, J.; Laher, R.; Conrow, T.; Kreidl, T.

2000-02-01

Inspired by the observations of low-amplitude oscillations of α Ursae Majoris A by Buzasi et al. using the WIRE satellite, a grid of stellar evolutionary tracks has been constructed to derive physically consistent interior models for the nearby red giant. The pulsation properties of these models were then calculated and compared with the observations. It is found that, by adopting the correct metallicity and for a normal helium abundance, only models in the mass range of 4.0-4.5 Msolar fall within the observational error box for α UMa A. This mass range is compatible, within the uncertainties, with the mass derived from the astrometric mass function. Analysis of the pulsation spectra of the models indicates that the observed α UMa oscillations can be most simply interpreted as radial (i.e., l=0) p-mode oscillations of low radial order n. The lowest frequencies observed by Buzasi et al. are compatible, within the observational errors, with model frequencies of radial orders n=0, 1, and 2 for models in the mass range of 4.0-4.5 Msolar. The higher frequencies observed can also be tentatively interpreted as higher n-valued radial p-modes, if we allow that some n-values are not presently observed. The theoretical l=1, 2, and 3 modes in the observed frequency range are g-modes with a mixed mode character, that is, with p-mode-like characteristics near the surface and g-mode-like characteristics in the interior. The calculated radial p-mode frequencies are nearly equally spaced, separated by 2-3 μHz. The nonradial modes are very densely packed throughout the observed frequency range and, even if excited to significant amplitudes at the surface, are unlikely to be resolved by the present observations.

Parameters affecting the frequency of a fluid oscillator

NASA Astrophysics Data System (ADS)

Cheng, R. M. H.; Kwok, C. K.; Lee, R. S.

1983-06-01

A new type of liquid-operated low-frequency oscillator is introduced. The oscillator consists of a cone-shaped housing with a fluid inlet and two outlet discharging tubes. The fluid discharge is controlled by a ball which blocks one of the outlet tubes. A strong vacuum develops due to the inertial effect of the column of liquid moving downward in the blocked tube. When the initial energy and velocity of the liquid slug are reduced to zero, it starts to return toward the ball. Eventually the combined force of the pressure inside the housing and the momentum of the upcoming slug is large enough to displace the ball to the other outlet tube, and the same procedure is then repeated. The main part of the paper consists of an analysis of the time required for the forward and reverse motion of the slug and for the ball to move from one discharge hole to the other.

Wideband-frequency tunable optoelectronic oscillator based on injection locking to an electronic oscillator.

PubMed

Fleyer, Michael; Sherman, Alexander; Horowitz, Moshe; Namer, Moshe

2016-05-01

We experimentally demonstrate a wideband-frequency tunable optoelectronic oscillator (OEO) based on injection locking of the OEO to a tunable electronic oscillator. The OEO cavity does not contain a narrowband filter and its frequency can be tuned over a broad bandwidth of 1 GHz. The injection locking is based on minimizing the injected power by adjusting the frequency of one of the OEO cavity modes to be approximately equal to the frequency of the injected signal. The phase noise that is obtained in the injection-locked OEO is similar to that obtained in a long-cavity self-sustained OEO. Although the cavity length of the OEO was long, the spurious modes were suppressed due to the injection locking without the need to use a narrowband filter. The spurious level was significantly below that obtained in a self-sustained OEO after inserting a narrowband electronic filter with a Q-factor of 720 into the cavity.

Low-cost FM oscillator for capacitance type of blade tip clearance measurement system

NASA Technical Reports Server (NTRS)

Barranger, John P.

1987-01-01

The frequency-modulated (FM) oscillator described is part of a blade tip clearance measurement system that meets the needs of a wide class of fans, compressors, and turbines. As a result of advancements in the technology of ultra-high-frequency operational amplifiers, the FM oscillator requires only a single low-cost integrated circuit. Its carrier frequency is 42.8 MHz when it is used with an integrated probe and connecting cable assembly consisting of a 0.81 cm diameter engine-mounted capacitance probe and a 61 cm long hermetically sealed coaxial cable. A complete circuit analysis is given, including amplifier negative resistance characteristics. An error analysis of environmentally induced effects is also derived, and an error-correcting technique is proposed. The oscillator can be calibrated in the static mode and has a negative peak frequency deviation of 400 kHz for a rotor blade thickness of 1.2 mm. High-temperature performance tests of the probe and 13 cm of the adjacent cable show good accuracy up to 600 C, the maximum permissible seal temperature. The major source of error is the residual FM oscillator noise, which produces a clearance error of + or - 10 microns at a clearance of 0.5 mm. The oscillator electronics accommodates the high rotor speeds associated with small engines, the signals from which may have frequency components as high as 1 MHz.

A Low-Power All-Digital on-Chip CMOS Oscillator for a Wireless Sensor Node

PubMed Central

Sheng, Duo; Hong, Min-Rong

2016-01-01

This paper presents an all-digital low-power oscillator for reference clocks in wireless body area network (WBAN) applications. The proposed on-chip complementary metal-oxide-semiconductor (CMOS) oscillator provides low-frequency clock signals with low power consumption, high delay resolution, and low circuit complexity. The cascade-stage structure of the proposed design simultaneously achieves high resolution and a wide frequency range. The proposed hysteresis delay cell further reduces the power consumption and hardware costs by 92.4% and 70.4%, respectively, relative to conventional designs. The proposed design is implemented in a standard performance 0.18 μm CMOS process. The measured operational frequency ranged from 7 to 155 MHz, and the power consumption was improved to 79.6 μW (@7 MHz) with a 4.6 ps resolution. The proposed design can be implemented in an all-digital manner, which is highly desirable for system-level integration. PMID:27754439

A Low-Power All-Digital on-Chip CMOS Oscillator for a Wireless Sensor Node.

PubMed

Sheng, Duo; Hong, Min-Rong

2016-10-14

This paper presents an all-digital low-power oscillator for reference clocks in wireless body area network (WBAN) applications. The proposed on-chip complementary metal-oxide-semiconductor (CMOS) oscillator provides low-frequency clock signals with low power consumption, high delay resolution, and low circuit complexity. The cascade-stage structure of the proposed design simultaneously achieves high resolution and a wide frequency range. The proposed hysteresis delay cell further reduces the power consumption and hardware costs by 92.4% and 70.4%, respectively, relative to conventional designs. The proposed design is implemented in a standard performance 0.18 μm CMOS process. The measured operational frequency ranged from 7 to 155 MHz, and the power consumption was improved to 79.6 μW (@7 MHz) with a 4.6 ps resolution. The proposed design can be implemented in an all-digital manner, which is highly desirable for system-level integration.

The measurement of linear frequency drift in oscillators

NASA Astrophysics Data System (ADS)

Barnes, J. A.

1985-04-01

A linear drift in frequency is an important element in most stochastic models of oscillator performance. Quartz crystal oscillators often have drifts in excess of a part in ten to the tenth power per day. Even commercial cesium beam devices often show drifts of a few parts in ten to the thirteenth per year. There are many ways to estimate the drift rates from data samples (e.g., regress the phase on a quadratic; regress the frequency on a linear; compute the simple mean of the first difference of frequency; use Kalman filters with a drift term as one element in the state vector; and others). Although most of these estimators are unbiased, they vary in efficiency (i.e., confidence intervals). Further, the estimation of confidence intervals using the standard analysis of variance (typically associated with the specific estimating technique) can give amazingly optimistic results. The source of these problems is not an error in, say, the regressions techniques, but rather the problems arise from correlations within the residuals. That is, the oscillator model is often not consistent with constraints on the analysis technique or, in other words, some specific analysis techniques are often inappropriate for the task at hand. The appropriateness of a specific analysis technique is critically dependent on the oscillator model and can often be checked with a simple whiteness test on the residuals.

Spectral-Temporal Evolution of Low-Frequency Pulsations in the Microwave Radiation of Solar Flares

NASA Astrophysics Data System (ADS)

Zaitsev, V. V.; Kislyakov, A. G.; Urpo, S.; Stepanov, A. V.; Shkelev, E. I.

2003-10-01

Low-frequency pulsations of 22 and 37 GHz microwave radiation detected during solar flares are analyzed. Several microwave bursts observed at the Metsähovi Radio Observatory are studied with time resolutions of 100 and 50 ms. A fast Fourier transformation with a sliding window and the Wigner-Ville method are used to obtain frequency-time diagrams for the low-frequency pulsations, which are interpreted as natural oscillations of coronal magnetic loops; the dynamical spectra of the pulsations are synthesized for the first time. Three types of low-frequency fluctuations modulating the flare microwave radiation can be distinguished in the observations. First, there are fast and slow magneto-acoustic oscillations with periods of 0.5 0.8 s and 200 280 s, respectively. The fast magneto-acoustic oscillations appear as trains of narrow-band signals with durations of 100 200 s, a positive frequency drift dν/dt=0.25 MHz/min, and frequency splitting δν=0.01 0.05 Hz. Second, there are natural oscillations of the coronal magnetic loops as equivalent electrical circuits. These oscillations have periods of 0.5 10 s and positive or negative frequency drift rates dν/dt=8×10-3 Hz/min or dν/dt=-1.3×10-2 Hz/min, depending on the phase of the radio outburst. Third, there are modulations of the microwave radiation by short periodic pulses with a period of 20 s. The dynamical spectra of the low-frequency pulsations supply important information about the parameters of the magnetic loops: the ratio of the loop radius to its length r/L≈0.1, the plasma parameter β≈10-3, the ratio of the plasma densities outside and inside the loop ρe/ρi≈10-2, and the electrical current flowing along the loop I≈1012 A.

Cryogenic sapphire oscillator using a low-vibration design pulse-tube cryocooler: first results.

PubMed

Hartnett, John; Nand, Nitin; Wang, Chao; Floch, Jean-Michel

2010-05-01

A cryogenic sapphire oscillator (CSO) has been implemented at 11.2 GHz using a low-vibration design pulsetube cryocooler. Compared with a state-of-the-art liquid helium cooled CSO in the same laboratory, the square root Allan variance of their combined fractional frequency instability is sigma(y) = 1.4 x 10(-15)tau(-1/2) for integration times 1 < tau < 10 s, dominated by white frequency noise. The minimum sigmay = 5.3 x 10(-16) for the two oscillators was reached at tau = 20 s. Assuming equal contributions from both CSOs, the single oscillator phase noise S(phi) approximately -96 dB x rad(2)/Hz at 1 Hz set from the carrier.

Trains of electrical stimulation of the trapezius muscles redistribute the frequencies of body oscillations during stance.

PubMed

Nhouvannasak, V; Clément, S; Manto, M

2015-09-01

We investigated the postural effects of trains of electrical stimulation (TES) applied unilaterally or bilaterally on the trapezius muscle in 20 healthy subjects (mean age: 23.1 ± 1.33 years; F/M: 8/12). The anterior-posterior (AP) displacements (AP axis), medio-lateral displacements (ML axis) and total travelled distances (TTW) of the centre of pressure (COP) remained unchanged with TES. However, detailed spectral analysis of COP oscillations revealed a marked decrease of the magnitudes of peak power spectral density (peak PSD) following application of TES. Peak PSD was highly correlated with the intensity of stimulation (P < 0.001 both the AP and ML axes). For the AP axis, the integrals of the sub-bands 0-0.4, 0.4-1.5, 1.5-3 Hz were significantly decreased (P < 0.001), the integrals of the sub-bands 3-5 and 5-8 Hz were not significantly affected (P>0.30) and the integrals of the sub-band 8-10 Hz were significantly increased (P < 0.001). The ratios of the integrals of sub-bands 8-10 Hz/0-3 Hz were markedly enhanced with bilateral TES (P < 0.001). For the ML axis, the effects were striking (P < 0.001) for the sub-bands 0-0.4, 0.4-1.5 and 8-10 Hz. For both the AP and ML axes, a significant inverse linear relationship was found between the intensity of TES and the average speed of COP. We show that TES applied over the trapezius muscles exerts significant and so far unrecognised effects upon oscillations of the COP, decreasing low-frequency oscillations and enhancing high-frequency oscillations. Our data unravel a novel property of the trapezius muscles upon postural control. We suggest that this muscle plays a role of a distributor of low-frequency versus high-frequency sub-bands of frequency during stance. Previous studies have shown that patients with supra-tentorial stroke show an increased peak PSD in low frequencies of body oscillations. Therefore, our findings provide a rationale to assess neurostimulation of the

Spectral modification of seismic waves propagating through solids exhibiting a resonance frequency: a 1-D coupled wave propagation-oscillation model

NASA Astrophysics Data System (ADS)

Frehner, Marcel; Schmalholz, Stefan M.; Podladchikov, Yuri

2009-02-01

A 1-D model is presented that couples the microscale oscillations of non-wetting fluid blobs in a partially saturated poroelastic medium with the macroscale wave propagation through the elastic skeleton. The fluid oscillations are caused by surface tension forces that act as the restoring forces driving the oscillations. The oscillations are described mathematically with the equation for a linear oscillator and the wave propagation is described with the 1-D elastic wave equation. Coupling is done using Hamilton's variational principle for continuous systems. The resulting linear system of two partial differential equations is solved numerically with explicit finite differences. Numerical simulations are used to analyse the effect of solids exhibiting internal oscillations, and consequently a resonance frequency, on seismic waves propagating through such media. The phase velocity dispersion relation shows a higher phase velocity in the high-frequency limit and a lower phase velocity in the low-frequency limit. At the resonance frequency a singularity in the dispersion relation occurs. Seismic waves can initiate oscillations of the fluid by transferring energy from solid to fluid at the resonance frequency. Due to this transfer, the spectral amplitude of the solid particle velocity decreases at the resonance frequency. After initiation, the oscillatory movement of the fluid continuously transfers energy at the resonance frequency back to the solid. Therefore, the spectral amplitude of the solid particle velocity is increased at the resonance frequency. Once initiated, fluid oscillations decrease in amplitude with increasing time. Consequently, the spectral peak of the solid particle velocity at the resonance frequency decreases with time.

Transient Modeling of Hybrid Rocket Low Frequency Instabilities

NASA Technical Reports Server (NTRS)

Karabeyoglu, M. Arif; DeZilwa, Shane; Cantwell, Brian; Zilliac, Greg

2003-01-01

A comprehensive dynamic model of a hybrid rocket has been developed in order to understand and predict the transient behavior including instabilities. A linearized version of the transient model predicted the low-frequency chamber pressure oscillations that are commonly observed in hybrids. The source of the instabilities is based on a complex coupling of thermal transients in the solid fuel, wall heat transfer blocking due to fuel regression rate and the transients in the boundary layer that forms on the fuel surface. The oscillation frequencies predicted by the linearized theory are in very good agreement with 43 motor test results obtained from the hybrid propulsion literature. The motor test results used in the comparison cover a very wide spectrum of parameters including: 1) four separate research and development programs, 2) three different oxidizers (LOX, GOX, N2O), 3) a wide range of motor dimensions (i.e. from 5 inch diameter to 72 inch diameter) and operating conditions and 4) several fuel formulations. A simple universal scaling formula for the frequency of the primary oscillation mode is suggested.

Evaluation of spontaneous low-frequency oscillations in cerebral hemodynamics with time-series red-green-blue images

NASA Astrophysics Data System (ADS)

Nishidate, Izumi; Mustari, Afrina; Nakamura, Naoki; Kawauchi, Satoko; Sato, Shunichi; Sato, Manabu; Kokubo, Yasuaki

2017-02-01

The brain relies on a continuous and adequate supply of blood flow, bringing the nutrients that it needs and removing the waste products of metabolism. It is thus one of the most tightly regulated systems in the body, whereby a whole range of mechanisms act to maintain this supply, despite changes in blood pressure etc. Failure of these mechanisms is found in a number of devastating cerebral diseases, including stroke, vascular dementia and brain injury and trauma. Spontaneous contraction and relaxation of arterioles (and in some instances venules) termed vasomotion has been observed in an extensive variety of tissues and species. Vasomotion has a beneficial effect on tissue oxygenation and enhance blood flow. Although vasomotion is strictly a local phenomenon, the regulation of contractile activity of vascular smooth muscle cells is dependent on the complex interplay between vasodilator and vasoconstrictor stimuli from circulating hormones, neurotransmitters, endothelial derived factors, and blood pressure. Therefore, evaluation of the spontaneous oscillations in cerebral vasculatures might be a useful tool for assessing risk and investigating different treatment strategies in neurological disorders, such as traumatic brain injury, seizure, ischemia, and stroke. In the present study, we newly propose a method to visualize the spontaneous low-frequency oscillation of cerebral blood volume based on the sequential RGB images of exposed brain.

Influence of the oscillation frequency of different side-to-side toothbrushes on noncontact biofilm removal.

PubMed

Schmidt, Julia C; Astasov-Frauenhoffer, Monika; Waltimo, Tuomas; Weiger, Roland; Walter, Clemens

2018-01-22

The objective of this study was to investigate the influence of different oscillation frequencies of three powered toothbrushes with side-to-side action for noncontact biofilm removal in an artificial interdental space model. A three-species biofilm (Porphyromonas gingivalis, Fusobacterium nucleatum and Streptococcus sanguinis) was formed in vitro on protein-coated titanium disks using a flow chamber system combined with a static biofilm growth model. The oscillation frequencies of three commercial side-to-side toothbrushes were evaluated by means of a dose response. The frequency was decreased in steps (100, 85, 70, 55, and 40%). Subsequently, the biofilm-coated substrates were exposed to the side-to-side toothbrushes. The biofilm volumes were measured using volumetric analyses (Imaris 8.1.2) with confocal laser scanning microscope images (Zeiss LSM700). Compared to maximum oscillation frequency (100%), lower oscillation frequencies (up to 40%) resulted in reduced median percentages of biofilm reduction (median biofilm reduction up to 53% for maximum oscillation frequency, and up to 13% for 40% oscillation frequency) (p ≥ 0.03). In addition, decreasing the oscillation frequencies of the side-to-side toothbrushes showed an enhanced variety in the results of repeated experiments. The oscillation frequency of the tested side-to-side toothbrushes affected the biofilm reduction in an interdental space model. Within a toothbrush, higher oscillation frequencies may lead to beneficial effects on interdental biofilm removal by noncontact brushing.

Granule cell excitability regulates gamma and beta oscillations in a model of the olfactory bulb dendrodendritic microcircuit

PubMed Central

Osinski, Bolesław L.

2016-01-01

Odors evoke gamma (40–100 Hz) and beta (20–30 Hz) oscillations in the local field potential (LFP) of the mammalian olfactory bulb (OB). Gamma (and possibly beta) oscillations arise from interactions in the dendrodendritic microcircuit between excitatory mitral cells (MCs) and inhibitory granule cells (GCs). When cortical descending inputs to the OB are blocked, beta oscillations are extinguished whereas gamma oscillations become larger. Much of this centrifugal input targets inhibitory interneurons in the GC layer and regulates the excitability of GCs, which suggests a causal link between the emergence of beta oscillations and GC excitability. We investigate the effect that GC excitability has on network oscillations in a computational model of the MC-GC dendrodendritic network with Ca2+-dependent graded inhibition. Results from our model suggest that when GC excitability is low, the graded inhibitory current mediated by NMDA channels and voltage-dependent Ca2+ channels (VDCCs) is also low, allowing MC populations to fire in the gamma frequency range. When GC excitability is increased, the activation of NMDA receptors and other VDCCs is also increased, allowing the slow decay time constants of these channels to sustain beta-frequency oscillations. Our model argues that Ca2+ flow through VDCCs alone could sustain beta oscillations and that the switch between gamma and beta oscillations can be triggered by an increase in the excitability state of a subpopulation of GCs. PMID:27121582

Dynamic electrical characteristics of low-power ring oscillators constructed with inorganic nanoparticles on flexible plastics.

PubMed

Yun, Junggwon; Cho, Kyoungah; Kim, Sangsig

2012-11-01

In this study, we demonstrate for the first time the low-power and stable performance of a ring oscillator constructed on a flexible plastic with solution-processable inorganic nanoparticles (NPs). Our flexible ring oscillator is composed of three inverters based on n- and p-type inorganic NP thin-film transistors. Each of the component inverters exhibits a gain of ∼80 at a voltage of 5 V. For the ring oscillator, the sine waves are generated with a frequency of up to 12 kHz. The waveforms are undistorted under strained conditions and maintained even after 5000 bending cycles. The frequency and waveform of the output waves obtained from our flexible ring oscillator are analyzed and discussed in detail.

The dark side of high-frequency oscillations in the developing brain.

PubMed

Le Van Quyen, Michel; Khalilov, Ilgam; Ben-Ari, Yehezkel

2006-07-01

Adult brain networks generate a wide range of oscillations. Some of these are behaviourally relevant, whereas others occur during seizures and other pathological conditions. This raises the question of how physiological oscillations differ from pathogenic ones. In this review, this issue is discussed from a developmental standpoint. Indeed, both epileptic and physiological high-frequency oscillations (HFOs) appear progressively during maturation, and it is therefore possible to determine how this program corresponds to maturation of the neuronal populations that generate these oscillations. We review here important differences in the development of neuronal populations that might contribute to their different oscillatory properties. In particular, at an early stage, the density of glutamatergic synapses is too low for physiological HFOs but an additional drive can be provided by excitatory GABA, triggering epileptic HFOs and the cascades involved in long-lasting epileptogenic transformations. This review is part of the INMED/TINS special issue "Nature and nurture in brain development and neurological disorders", based on presentations at the annual INMED/TINS symposium (http://inmednet.com/).

Photoinduced High-Frequency Charge Oscillations in Dimerized Systems

NASA Astrophysics Data System (ADS)

Yonemitsu, Kenji

2018-04-01

Photoinduced charge dynamics in dimerized systems is studied on the basis of the exact diagonalization method and the time-dependent Schrödinger equation for a one-dimensional spinless-fermion model at half filling and a two-dimensional model for κ-(bis[ethylenedithio]tetrathiafulvalene)2X [κ-(BEDT-TTF)2X] at three-quarter filling. After the application of a one-cycle pulse of a specifically polarized electric field, the charge densities at half of the sites of the system oscillate in the same phase and those at the other half oscillate in the opposite phase. For weak fields, the Fourier transform of the time profile of the charge density at any site after photoexcitation has peaks for finite-sized systems that correspond to those of the steady-state optical conductivity spectrum. For strong fields, these peaks are suppressed and a new peak appears on the high-energy side, that is, the charge densities mainly oscillate with a single frequency, although the oscillation is eventually damped. In the two-dimensional case without intersite repulsion and in the one-dimensional case, this frequency corresponds to charge-transfer processes by which all the bonds connecting the two classes of sites are exploited. Thus, this oscillation behaves as an electronic breathing mode. The relevance of the new peak to a recently found reflectivity peak in κ-(BEDT-TTF)2X after photoexcitation is discussed.

The Phosphorylation State of the Drosophila TRP Channel Modulates the Frequency Response to Oscillating Light In Vivo

PubMed Central

Rhodes-Mordov, Elisheva; Katz, Ben; Oberegelsbacher, Claudia; Yasin, Bushra; Tzadok, Hanan; Huber, Armin

2017-01-01

Drosophila photoreceptors respond to oscillating light of high frequency (∼100 Hz), while the detected maximal frequency is modulated by the light rearing conditions, thus enabling high sensitivity to light and high temporal resolution. However, the molecular basis for this adaptive process is unclear. Here, we report that dephosphorylation of the light-activated transient receptor potential (TRP) ion channel at S936 is a fast, graded, light-dependent, and Ca2+-dependent process that is partially modulated by the rhodopsin phosphatase retinal degeneration C (RDGC). Electroretinogram measurements of the frequency response to oscillating lights in vivo revealed that dark-reared flies expressing wild-type TRP exhibited a detection limit of oscillating light at relatively low frequencies, which was shifted to higher frequencies upon light adaptation. Strikingly, preventing phosphorylation of the S936-TRP site by alanine substitution in transgenic Drosophila (trpS936A) abolished the difference in frequency response between dark-adapted and light-adapted flies, resulting in high-frequency response also in dark-adapted flies. In contrast, inserting a phosphomimetic mutation by substituting the S936-TRP site to aspartic acid (trpS936D) set the frequency response of light-adapted flies to low frequencies typical of dark-adapted flies. Light-adapted rdgC mutant flies showed relatively high S936-TRP phosphorylation levels and light–dark phosphorylation dynamics. These findings suggest that RDGC is one but not the only phosphatase involved in pS936-TRP dephosphorylation. Together, this study indicates that TRP channel dephosphorylation is a regulatory process that affects the detection limit of oscillating light according to the light rearing condition, thus adjusting dynamic processing of visual information under varying light conditions. SIGNIFICANCE STATEMENT Drosophila photoreceptors exhibit high temporal resolution as manifested in frequency response to oscillating

Optoelectronic oscillator with improved phase noise and frequency stability

NASA Astrophysics Data System (ADS)

Eliyahu, Danny; Sariri, Kouros; Taylor, Joseph; Maleki, Lute

2003-07-01

In this paper we report on recent improvements in phase noise and frequency stability of a 10 GHz opto-electronic oscillator. In our OEO loop, the high Q elements (the optical fiber and the narrow bandpass microwave filter) are thermally stabilized using resistive heaters and temperature controllers, keeping their temperature above ambient. The thermally stabilized free running OEO demonstrates a short-term frequency stability of 0.02 ppm (over several hours) and frequency vs. temperature slope of -0.1 ppm/°C (compared to -8.3 ppm/°C for non thermally stabilized OEO). We obtained an exceptional spectral purity with phase noise level of -143 dBc/Hz at 10 kHz of offset frequency. We also describe the multi-loop configuration that reduces dramatically the spurious level at offset frequencies related to the loop round trip harmonic frequency. The multi-loop configuration has stronger mode selectivity due to interference between signals having different cavity lengths. A drop of the spurious level below -90 dBc was demonstrated. The effect of the oscillator aging on the frequency stability was studied as well by recording the oscillator frequency (in a chamber) over several weeks. We observed reversal in aging direction with logarithmic behavior of A ln(B t+1)-C ln(D t+1), where t is the time and A, B, C, D are constants. Initially, in the first several days, the positive aging dominates. However, later the negative aging mechanism dominates. We have concluded that the long-term aging behavioral model is consistent with the experimental results.

Noninvasive optical evaluation of low frequency oscillations in prefrontal cortex hemodynamics during verbal working memory

NASA Astrophysics Data System (ADS)

Li, Ting; Zhao, Yue; Li, Kai; Sun, Yunlong

2014-03-01

The low frequency oscillation (LFO) around 0.1 Hz has been observed recently in cerebral hemodynamic signals during rest/sleep, enhanced breathing, and head- up-tilting, showing that cerebral autoregulation can be accessed by LFOs. However, many brain function researches require direct measurement of LFOs during specified brain function activities. This pilot study explored using near-infrared spectroscopy/imaging (NIRS) to noninvasively and simultaneously detect LFOs of prefrontal cerebral hemodynamics (i.e., oxygenated/deoxygenated/total hemoglobin concentration: △[oxy-Hb]/ △[deoxy-Hb]/ △[tot-Hb]) during N-back visual verbal working memory task. The LFOs were extracted from the measured variables using power spectral analysis. We found the brain activation sites struck clear LFOs while other sites did not. The LFO of △[deoxy-Hb] acted as a negative pike and ranged in (0.05, 0.1) Hz, while LFOs of △[oxy-Hb] and △[tot-Hb] acted as a positive pike and ranged in (0.1, 0.15) Hz. The amplitude difference and frequency lag between △[deoxy-Hb] and △[oxy-Hb]/ △[tot-Hb] produced a more focused and sensitive activation map compare to hemodynamic amplitude-quantified activation maps. This study observed LFOs in brain activities and showed strong potential of LFOs in accessing brain functions.

Fluidic Oscillator Having Decoupled Frequency and Amplitude Control

NASA Technical Reports Server (NTRS)

Koklu, Mehti (Inventor)

2016-01-01

A fluidic oscillator having independent frequency and amplitude control includes a fluidic-oscillator main flow channel having a main flow inlet, a main flow outlet, and first and second control ports disposed at opposing sides thereof. A fluidic-oscillator controller has an inlet and outlet. A volume defined by the main flow channel is greater than the volume defined by the controller. A flow diverter coupled to the outlet of the controller defines a first fluid flow path from the controller's outlet to the first control port and defines a second fluid flow path from the controller's outlet to the second control port.

Fluidic Oscillator Having Decoupled Frequency and Amplitude Control

NASA Technical Reports Server (NTRS)

Koklu, Mehti (Inventor)

2017-01-01

A fluidic oscillator having independent frequency and amplitude control includes a fluidic-oscillator main flow channel having a main flow inlet, a main flow outlet, and first and second control ports disposed at opposing sides thereof. A fluidic-oscillator controller has an inlet and outlet. A volume defined by the main flow channel is greater than the volume defined by the controller. A flow diverter coupled to the outlet of the controller defines a first fluid flow path from the controller's outlet to the first control port and defines a second fluid flow path from the controller's outlet to the second control port.

Experimental study of the influence of low frequency flow modulation on the whistling behavior of a corrugated pipe.

PubMed

Kristiansen, Ulf R; Mattei, Pierre-Olivier; Pinhede, Cedric; Amielh, Muriel

2011-10-01

It is well known that airflow in a corrugated pipe can excite whistling at the frequencies of the pipe's longitudinal acoustic modes. This short contribution reports on the results of experiments where a low frequency, oscillating flow with velocity magnitudes of the same order as the airflow has been added. Depending on the oscillation strength, it has been found that this flow may silence the pipe or move the whistling to higher harmonics. It is also shown that the low frequency oscillation itself may excite higher frequency whistling sounds in the pipe. © 2011 Acoustical Society of America

High-frequency neural oscillations and visual processing deficits in schizophrenia

PubMed Central

Tan, Heng-Ru May; Lana, Luiz; Uhlhaas, Peter J.

2013-01-01

Visual information is fundamental to how we understand our environment, make predictions, and interact with others. Recent research has underscored the importance of visuo-perceptual dysfunctions for cognitive deficits and pathophysiological processes in schizophrenia. In the current paper, we review evidence for the relevance of high frequency (beta/gamma) oscillations towards visuo-perceptual dysfunctions in schizophrenia. In the first part of the paper, we examine the relationship between beta/gamma band oscillations and visual processing during normal brain functioning. We then summarize EEG/MEG-studies which demonstrate reduced amplitude and synchrony of high-frequency activity during visual stimulation in schizophrenia. In the final part of the paper, we identify neurobiological correlates as well as offer perspectives for future research to stimulate further inquiry into the role of high-frequency oscillations in visual processing impairments in the disorder. PMID:24130535

Frequency equation for the submicron CMOS ring oscillator using the first order characterization

NASA Astrophysics Data System (ADS)

Koithyar, Aravinda; Ramesh, T. K.

2018-05-01

By utilizing the first order behavior of the device, an equation for the frequency of operation of the submicron CMOS ring oscillator is presented. A 5-stage ring oscillator is utilized as the initial design, with different Beta ratios, for the computation of the operating frequency. Later on, the circuit simulation is performed from 5-stage till 23-stage, with the range of oscillating frequency being 3.0817 and 0.6705 GHz respectively. It is noted that the output frequency is inversely proportional to the square of the device length, and when the value of Beta ratio is used as 2.3, a difference of 3.64% is observed on an average, in between the computed and the simulated values of frequency. As an outcome, the derived equation can be utilized, with the inclusion of an empirical constant in general, for arriving at the ring oscillator circuit’s output frequency.

A microwave exciter for Cs frequency standards based on a sapphire-loaded cavity oscillator.

PubMed

Koga, Y; McNeilage, C; Searls, J H; Ohshima, S

2001-01-01

A low noise and highly stable microwave exciter system has been built for Cs atomic frequency standards using a tunable sapphire-loaded cavity oscillator (SLCO), which works at room temperature. This paper discusses the successful implementation of a control system for locking the SLCO to a long-term reference signal and reports an upper limit of the achieved frequency tracking error 6 x 10(-15) at tau = 1 s.

Regulation of NF-κB Oscillation by Nuclear Transport: Mechanisms Determining the Persistency and Frequency of Oscillation

PubMed Central

Ohshima, Daisuke; Ichikawa, Kazuhisa

2015-01-01

The activated transcription factor NF-κB shuttles between the cytoplasm and the nucleus resulting in the oscillation of nuclear NF-κB (NF-κBn). The oscillation pattern of NF-κBn is implicated in the regulation of gene expression profiles. Using computational models, we previously reported that spatial parameters, such as the diffusion coefficient, nuclear to cytoplasmic volume ratio, transport through the nuclear envelope, and the loci of translation of IκB protein, modified the oscillation pattern of NF-κBn. In a subsequent report, we elucidated the importance of the “reset” of NF-κBn (returning of NF-κB to the original level) and of a “reservoir” of IκB in the cytoplasm. When the diffusion coefficient of IκB was large, IκB stored at a distant location from the nucleus diffused back to the nucleus and “reset” NF-κBn. Herein, we report mechanisms that regulate the persistency and frequency of NF-κBn oscillation by nuclear transport. Among the four parameters of nuclear transport tested in our spatio-temporal computational model, the export of IκB mRNA from the nucleus regulated the persistency of oscillation. The import of IκB to the nucleus regulated the frequency of oscillation. The remaining two parameters, import and export of NF-κB to and from the nucleus, had virtually no effect on the persistency or frequency. Our analyses revealed that lesser export of IκB mRNA allowed NF-κBn to transcript greater amounts of IκB mRNA, which was retained in the nucleus, and was subsequently exported to the cytoplasm, where large amounts of IκB were synthesized to “reset” NF-κBn and drove the persistent oscillation. On the other hand, import of greater amounts of IκB led to an increase in the influx and the efflux of NF-κB to and from the nucleus, resulting in an increase in the oscillation frequency. Our study revealed the importance of nuclear transport in regulating the oscillation pattern of NF-κBn. PMID:26042739

Robust synchronization of coupled circadian and cell cycle oscillators in single mammalian cells.

PubMed

Bieler, Jonathan; Cannavo, Rosamaria; Gustafson, Kyle; Gobet, Cedric; Gatfield, David; Naef, Felix

2014-07-15

Circadian cycles and cell cycles are two fundamental periodic processes with a period in the range of 1 day. Consequently, coupling between such cycles can lead to synchronization. Here, we estimated the mutual interactions between the two oscillators by time-lapse imaging of single mammalian NIH3T3 fibroblasts during several days. The analysis of thousands of circadian cycles in dividing cells clearly indicated that both oscillators tick in a 1:1 mode-locked state, with cell divisions occurring tightly 5 h before the peak in circadian Rev-Erbα-YFP reporter expression. In principle, such synchrony may be caused by either unidirectional or bidirectional coupling. While gating of cell division by the circadian cycle has been most studied, our data combined with stochastic modeling unambiguously show that the reverse coupling is predominant in NIH3T3 cells. Moreover, temperature, genetic, and pharmacological perturbations showed that the two interacting cellular oscillators adopt a synchronized state that is highly robust over a wide range of parameters. These findings have implications for circadian function in proliferative tissues, including epidermis, immune cells, and cancer. © 2014 The Authors. Published under the terms of the CC BY 4.0 license.

Dependence of synchronization on frequency mismatch and network configuration in chemo-mechanical oscillators

NASA Astrophysics Data System (ADS)

Kumar, Pawan; Parmananda, P.

2018-04-01

In this paper, synchronization among the mercury beating heart (MBH) oscillators is studied. In the first set of experiments, two MBH oscillators were taken. Frequency of one oscillator is kept constant and that of the other is increased monotonically. These were then coupled using bidirectional and unidirectional coupling mechanisms separately. Dependence of synchronization on the frequency difference between the two oscillators is investigated. For the second set of experiments involving unidirectional coupling, an ensemble of fifteen oscillators was taken and different configurations of these oscillators were considered. These include an all-to-all network and fractionally distributed master slave configurations. The effect of both the extent of coupling and network configuration on synchronization among these oscillators was investigated.

High frequency oscillations are associated with cognitive processing in human recognition memory.

PubMed

Kucewicz, Michal T; Cimbalnik, Jan; Matsumoto, Joseph Y; Brinkmann, Benjamin H; Bower, Mark R; Vasoli, Vincent; Sulc, Vlastimil; Meyer, Fred; Marsh, W R; Stead, S M; Worrell, Gregory A

2014-08-01

High frequency oscillations are associated with normal brain function, but also increasingly recognized as potential biomarkers of the epileptogenic brain. Their role in human cognition has been predominantly studied in classical gamma frequencies (30-100 Hz), which reflect neuronal network coordination involved in attention, learning and memory. Invasive brain recordings in animals and humans demonstrate that physiological oscillations extend beyond the gamma frequency range, but their function in human cognitive processing has not been fully elucidated. Here we investigate high frequency oscillations spanning the high gamma (50-125 Hz), ripple (125-250 Hz) and fast ripple (250-500 Hz) frequency bands using intracranial recordings from 12 patients (five males and seven females, age 21-63 years) during memory encoding and recall of a series of affectively charged images. Presentation of the images induced high frequency oscillations in all three studied bands within the primary visual, limbic and higher order cortical regions in a sequence consistent with the visual processing stream. These induced oscillations were detected on individual electrodes localized in the amygdala, hippocampus and specific neocortical areas, revealing discrete oscillations of characteristic frequency, duration and latency from image presentation. Memory encoding and recall significantly modulated the number of induced high gamma, ripple and fast ripple detections in the studied structures, which was greater in the primary sensory areas during the encoding (Wilcoxon rank sum test, P = 0.002) and in the higher-order cortical association areas during the recall (Wilcoxon rank sum test, P = 0.001) of memorized images. Furthermore, the induced high gamma, ripple and fast ripple responses discriminated the encoded and the affectively charged images. In summary, our results show that high frequency oscillations, spanning a wide range of frequencies, are associated with memory processing and

Injection locked coupled opto-electronic oscillator for optical frequency comb generation

NASA Astrophysics Data System (ADS)

Williams, Charles; Mandridis, Dimitrios; Davila-Rodriguez, Josue; Delfyett, Peter J.

2011-06-01

A CW injection locked Coupled Opto-Electronic Oscillator (COEO) is presented with a 10.24 GHz spaced optical frequency comb output as well as a low noise RF output. A modified Pound-Drever-Hall scheme is employed to ensure long-term stability of the injection lock, feeding back into the cavity length to compensate for cavity resonance drifts relative to the injection seed frequency. Error signal comparison to an actively mode-locked injection locked laser is presented. High optical signal-to-noise ratio of ~35 dB is demonstrated with >20 comblines of useable bandwidth. The optical linewidth, in agreement with injection locking theory, reduces to that of the injection seed frequency, <5 kHz. Low amplitude and absolute phase noise are presented from the optical output of the laser system. The integrated pulse-to-pulse energy fluctuation was found to be reduced by up to a factor of two due to optical injection. Additional decreases were shown for varying injection powers.

Effect of section shape on frequencies of natural oscillations of tubular springs

NASA Astrophysics Data System (ADS)

Pirogov, S. P.; Chuba, A. Yu; Cherentsov, D. A.

2018-05-01

The necessity of determining the frequencies of natural oscillations of manometric tubular springs is substantiated. Based on the mathematical model and computer program, numerical experiments were performed that allowed us to reveal the effect of geometric parameters on the frequencies of free oscillations of manometric tubular springs.

The low-power potential of oven-controlled MEMS oscillators.

PubMed

Vig, John; Kim, Yoonkee

2013-04-01

It is shown that oven-controlled micro electromechanical systems (MEMS) oscillators have the potential of attaining a higher frequency stability, with a lower power consumption, than temperature-compensated crystal oscillators (TCXOs) and the currently manufactured MEMS oscillators.

Low frequency steady-state brain responses modulate large scale functional networks in a frequency-specific means.

PubMed

Wang, Yi-Feng; Long, Zhiliang; Cui, Qian; Liu, Feng; Jing, Xiu-Juan; Chen, Heng; Guo, Xiao-Nan; Yan, Jin H; Chen, Hua-Fu

2016-01-01

Neural oscillations are essential for brain functions. Research has suggested that the frequency of neural oscillations is lower for more integrative and remote communications. In this vein, some resting-state studies have suggested that large scale networks function in the very low frequency range (<1 Hz). However, it is difficult to determine the frequency characteristics of brain networks because both resting-state studies and conventional frequency tagging approaches cannot simultaneously capture multiple large scale networks in controllable cognitive activities. In this preliminary study, we aimed to examine whether large scale networks can be modulated by task-induced low frequency steady-state brain responses (lfSSBRs) in a frequency-specific pattern. In a revised attention network test, the lfSSBRs were evoked in the triple network system and sensory-motor system, indicating that large scale networks can be modulated in a frequency tagging way. Furthermore, the inter- and intranetwork synchronizations as well as coherence were increased at the fundamental frequency and the first harmonic rather than at other frequency bands, indicating a frequency-specific modulation of information communication. However, there was no difference among attention conditions, indicating that lfSSBRs modulate the general attention state much stronger than distinguishing attention conditions. This study provides insights into the advantage and mechanism of lfSSBRs. More importantly, it paves a new way to investigate frequency-specific large scale brain activities. © 2015 Wiley Periodicals, Inc.

Neural Cross-Frequency Coupling: Connecting Architectures, Mechanisms, and Functions.

PubMed

Hyafil, Alexandre; Giraud, Anne-Lise; Fontolan, Lorenzo; Gutkin, Boris

2015-11-01

Neural oscillations are ubiquitously observed in the mammalian brain, but it has proven difficult to tie oscillatory patterns to specific cognitive operations. Notably, the coupling between neural oscillations at different timescales has recently received much attention, both from experimentalists and theoreticians. We review the mechanisms underlying various forms of this cross-frequency coupling. We show that different types of neural oscillators and cross-frequency interactions yield distinct signatures in neural dynamics. Finally, we associate these mechanisms with several putative functions of cross-frequency coupling, including neural representations of multiple environmental items, communication over distant areas, internal clocking of neural processes, and modulation of neural processing based on temporal predictions. Copyright © 2015 Elsevier Ltd. All rights reserved.

Resonance frequencies of lipid-shelled microbubbles in the regime of nonlinear oscillations

PubMed Central

Doinikov, Alexander A.; Haac, Jillian F.; Dayton, Paul A.

2009-01-01

Knowledge of resonant frequencies of contrast microbubbles is important for the optimization of ultrasound contrast imaging and therapeutic techniques. To date, however, there are estimates of resonance frequencies of contrast microbubbles only for the regime of linear oscillation. The present paper proposes an approach for evaluating resonance frequencies of contrast agent microbubbles in the regime of nonlinear oscillation. The approach is based on the calculation of the time-averaged oscillation power of the radial bubble oscillation. The proposed procedure was verified for free bubbles in the frequency range 1–4 MHz and then applied to lipid-shelled microbubbles insonified with a single 20-cycle acoustic pulse at two values of the acoustic pressure amplitude, 100 kPa and 200 kPa, and at four frequencies: 1.5, 2.0, 2.5, and 3.0 MHz. It is shown that, as the acoustic pressure amplitude is increased, the resonance frequency of a lipid-shelled microbubble tends to decrease in comparison with its linear resonance frequency. Analysis of existing shell models reveals that models that treat the lipid shell as a linear viscoelastic solid appear may be challenged to provide the observed tendency in the behavior of the resonance frequency at increasing acoustic pressure. The conclusion is drawn that the further development of shell models could be improved by the consideration of nonlinear rheological laws. PMID:18977009

Photonic harmonic up-converter based on a self-oscillating optical frequency comb using a DP-DPMZM

NASA Astrophysics Data System (ADS)

Xiao, Xuedi; Li, Shangyuan; Xie, Zhengyang; Peng, Shaowen; Wu, Dexin; Xue, Xiaoxiao; Zheng, Xiaoping; Zhou, Bingkun

2018-04-01

A photonic harmonic up-converter based on a self-oscillating optical frequency comb (OFC) utilizing an integrated dual-polarization dual-parallel Mach-Zehnder Modulator (DP-DPMZM) is proposed and experimentally demonstrated. One DPMZM is used to generate the optoelectronic oscillator (OEO)-based OFC, and the rest one is used to generate the optical-modulated intermediate frequency (IF) signal. Beating these two signals, the up-converted signals at different bands would be obtained. As the OFC is generated based on the OEO loop, phase noise can be very low, ensuring good phase noise properties of the up-converted signals. Moreover, frequency spacing between the combs is dependent on oscillating frequency of the OEO, which can be as large as tens of gigahertz. Thus IF signals with large bandwidth can be up-converted to RF bands without aliasing. Experimentally, the 2.5 GHz IF signal is simultaneously up-converted to 13.3, 24.1, and 34.9 GHz by a self-oscillating 7-line OFC spacing at 10.8 GHz. Owing to good phase noise property of the OEO, the up-converted signals at 13.3 and 24.1 GHz maintain the phase noise of the IF signal from 1 KHz to 100 KHz offset. The results show that the converter is promising for multi-band radar and satellite navigation applications.

The Effect of Atmospheric Diabatic Heating on Low-Frequency Oscillations.

NASA Astrophysics Data System (ADS)

Yen, Ming-Cheng

1990-01-01

A diagnostic scheme is devised to illustrate a chain relationship between diabatic heating and planetary -scale divergent and rotational circulations. The scheme consists of the velocity-potential (chi) maintenance equation, which relates diabatic heating and velocity potential, and the streamfunction (psi ) budget equation, which depicts the streamfunction tendency caused by the imbalance between streamfunction tendencies induced by vorticity advection and source. The proposed scheme is employed to examine the effect of tropical diabatic heating on the annual variation of subtropical jet streams. Furthermore, the chi -maintenance analysis is used to examine how the 30-60 day oscillation of planetary-scale divergent circulation is maintained; and the psi-budget analysis is performed to illustrate how the 30-60 day velocity potential (~{chi}) mode interacts with the upper-level monsoon flow to induce the 30-60 day oscillation of the tropical easterly jet. It was found that annual variations of both tropical diabatic heating and planetary-scale divergent circulation exhibit an annual in-phase seesaw oscillation between the winter and summer hemispheres. The annual variation of subtropical jet streams is caused by the adjustment of atmospheric rotational flow through planetary-scale divergent circulation in response to the annual cycle of tropical diabatic heating. The chi-maintenance equation is expressed as chi = chi _sp{rm Q}{.} - chi_{rm HA} , where chi_sp{rm Q}{.} and chi_ {rm HA} are the effects of vertical differential diabatic and adiabatic heating, respectively. The 30-60 day chi oscillation is shown to be primarily maintained by the differential diabatic heating effect, which can be inferred from the H _{rm VD} anomalies, the Laplician of the filtered chi_sp{rm Q}{.} anomalies. The resemblance of the H_{rm VD} and OLR anomalies in terms of the geographic distributions indicates that the differential diabatic heating effect maintaining the 30-60 day chi

The quasi-periodic oscillations and very low frequency noise of Scorpius X-1 as transient chaos - A dripping handrail?

NASA Technical Reports Server (NTRS)

Scargle, Jeffrey D.; Steiman-Cameron, Thomas; Young, Karl; Donoho, David L.; Crutchfield, James P.; Imamura, James

1993-01-01

We present evidence that the quasi-periodic oscillations (QPO) and very low frequency noise (VLFN) characteristic of many accretion sources are different aspects of the same physical process. We analyzed a long, high time resolution EXOSAT observation of the low-mass X-ray binary (LMXB) Sco X-1. The X-ray luminosity varies stochastically on time scales from milliseconds to hours. The nature of this variability - as quantified with both power spectrum analysis and a new wavelet technique, the scalegram - agrees well with the dripping handrail accretion model, a simple dynamical system which exhibits transient chaos. In this model both the QPO and VLFN are produced by radiation from blobs with a wide size distribution, resulting from accretion and subsequent diffusion of hot gas, the density of which is limited by an unspecified instability to lie below a threshold.

The detection and characterization of high frequency and high wavenumber solar oscillations. Ph.D. Thesis

NASA Technical Reports Server (NTRS)

Fernandes, David Neil

1992-01-01

Doppler shift measurements of the Na D(sub 1) absorption line have revealed solar oscillations in a new regime of frequency and wavenumber. Oscillations of vertical velocities in the temperature minimum and low chromosphere of the Sun are observed with frequencies ranging up to 9.5 mHz. There is no evidence for chromospheric modes of 3 minute period. This indicates that the chromosphere does not form a good cavity for acoustic waves. The fundamental-modes appear with wavenumbers up to 5.57 M per m (equivalent spherical harmonic degree, 3877). The frequencies lie below the predicted values at wavenumbers above 1 M per m. The values are in agreement with previous measurements that exist for wavenumbers up to 2.67 M per m. Spatial maps of velocity power show that high wavenumber oscillations are suppressed in active regions. The shape of the power depression indicates that wave motion is affected in the layer of atmosphere where the measurement is made. The f-modes are suppressed in the same way as p-modes, indicating that the mechanism for wave suppression affects velocity fluctuations. Mode frequencies are not affected by the magnetic fields by more than 50 micro Hz, the precision of the measurement.

Temporal fluxomics reveals oscillations in TCA cycle flux throughout the mammalian cell cycle.

PubMed

Ahn, Eunyong; Kumar, Praveen; Mukha, Dzmitry; Tzur, Amit; Shlomi, Tomer

2017-11-06

Cellular metabolic demands change throughout the cell cycle. Nevertheless, a characterization of how metabolic fluxes adapt to the changing demands throughout the cell cycle is lacking. Here, we developed a temporal-fluxomics approach to derive a comprehensive and quantitative view of alterations in metabolic fluxes throughout the mammalian cell cycle. This is achieved by combining pulse-chase LC-MS-based isotope tracing in synchronized cell populations with computational deconvolution and metabolic flux modeling. We find that TCA cycle fluxes are rewired as cells progress through the cell cycle with complementary oscillations of glucose versus glutamine-derived fluxes: Oxidation of glucose-derived flux peaks in late G1 phase, while oxidative and reductive glutamine metabolism dominates S phase. These complementary flux oscillations maintain a constant production rate of reducing equivalents and oxidative phosphorylation flux throughout the cell cycle. The shift from glucose to glutamine oxidation in S phase plays an important role in cell cycle progression and cell proliferation. © 2017 The Authors. Published under the terms of the CC BY 4.0 license.

Fatigue Effect on Low-Frequency Force Fluctuations and Muscular Oscillations during Rhythmic Isometric Contraction

PubMed Central

Lin, Yen-Ting; Kuo, Chia-Hua; Hwang, Ing-Shiou

2014-01-01

Continuous force output containing numerous intermittent force pulses is not completely smooth. By characterizing force fluctuation properties and force pulse metrics, this study investigated adaptive changes in trajectory control, both force-generating capacity and force fluctuations, as fatigue progresses. Sixteen healthy subjects (20–24 years old) completed rhythmic isometric gripping with the non-dominant hand to volitional failure. Before and immediately following the fatigue intervention, we measured the gripping force to couple a 0.5 Hz sinusoidal target in the range of 50–100% maximal voluntary contraction. Dynamic force output was off-line decomposed into 1) an ideal force trajectory spectrally identical to the target rate; and 2) a force pulse trace pertaining to force fluctuations and error-correction attempts. The amplitude of ideal force trajectory regarding to force-generating capacity was more suppressed than that of the force pulse trace with increasing fatigue, which also shifted the force pulse trace to lower frequency bands. Multi-scale entropy analysis revealed that the complexity of the force pulse trace at high time scales increased with fatigue, contrary to the decrease in complexity of the force pulse trace at low time scales. Statistical properties of individual force pulses in the spatial and temporal domains varied with muscular fatigue, concurrent with marked suppression of gamma muscular oscillations (40–60 Hz) in the post-fatigue test. In conclusion, this study first reveals that muscular fatigue impairs the amplitude modulation of force pattern generation more than it affects the amplitude responsiveness of fine-tuning a force trajectory. Besides, motor fatigue results disadvantageously in enhancement of motor noises, simplification of short-term force-tuning strategy, and slow responsiveness to force errors, pertaining to dimensional changes in force fluctuations, scaling properties of force pulse, and muscular oscillation

Phase locking and multiple oscillating attractors for the coupled mammalian clock and cell cycle.

PubMed

Feillet, Céline; Krusche, Peter; Tamanini, Filippo; Janssens, Roel C; Downey, Mike J; Martin, Patrick; Teboul, Michèle; Saito, Shoko; Lévi, Francis A; Bretschneider, Till; van der Horst, Gijsbertus T J; Delaunay, Franck; Rand, David A

2014-07-08

Daily synchronous rhythms of cell division at the tissue or organism level are observed in many species and suggest that the circadian clock and cell cycle oscillators are coupled. For mammals, despite known mechanistic interactions, the effect of such coupling on clock and cell cycle progression, and hence its biological relevance, is not understood. In particular, we do not know how the temporal organization of cell division at the single-cell level produces this daily rhythm at the tissue level. Here we use multispectral imaging of single live cells, computational methods, and mathematical modeling to address this question in proliferating mouse fibroblasts. We show that in unsynchronized cells the cell cycle and circadian clock robustly phase lock each other in a 1:1 fashion so that in an expanding cell population the two oscillators oscillate in a synchronized way with a common frequency. Dexamethasone-induced synchronization reveals additional clock states. As well as the low-period phase-locked state there are distinct coexisting states with a significantly higher period clock. Cells transition to these states after dexamethasone synchronization. The temporal coordination of cell division by phase locking to the clock at a single-cell level has significant implications because disordered circadian function is increasingly being linked to the pathogenesis of many diseases, including cancer.

Ionization oscillations in Hall accelerators

NASA Astrophysics Data System (ADS)

Barral, S.; Peradzyński, Z.

2010-01-01

The underlying mechanism of low-frequency oscillations in Hall accelerators is investigated theoretically. It is shown that relaxation oscillations arise from a competition between avalanche ionization and the advective transport of the working gas. The model derived recovers the slow progression and fast recession of the ionization front. Analytical approximations of the shape of current pulses and of the oscillation frequency are provided for the case of large amplitude oscillations.

SOLAR-LIKE OSCILLATIONS IN LOW-LUMINOSITY RED GIANTS: FIRST RESULTS FROM KEPLER

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bedding, T. R.; Huber, D.; Stello, D.

2010-04-20

We have measured solar-like oscillations in red giants using time-series photometry from the first 34 days of science operations of the Kepler Mission. The light curves, obtained with 30 minute sampling, reveal clear oscillations in a large sample of G and K giants, extending in luminosity from the red clump down to the bottom of the giant branch. We confirm a strong correlation between the large separation of the oscillations ({delta}{nu}) and the frequency of maximum power ({nu}{sub max}). We focus on a sample of 50 low-luminosity stars ({nu}{sub max} > 100 {mu}Hz, L {approx}< 30 L {sub sun}) havingmore » high signal-to-noise ratios and showing the unambiguous signature of solar-like oscillations. These are H-shell-burning stars, whose oscillations should be valuable for testing models of stellar evolution and for constraining the star formation rate in the local disk. We use a new technique to compare stars on a single echelle diagram by scaling their frequencies and find well-defined ridges corresponding to radial and non-radial oscillations, including clear evidence for modes with angular degree l = 3. Measuring the small separation between l = 0 and l = 2 allows us to plot the so-called C-D diagram of {delta}{nu}{sub 02} versus {delta}{nu}. The small separation {delta}{nu}{sub 01} of l = 1 from the midpoint of adjacent l = 0 modes is negative, contrary to the Sun and solar-type stars. The ridge for l = 1 is notably broadened, which we attribute to mixed modes, confirming theoretical predictions for low-luminosity giants. Overall, the results demonstrate the tremendous potential of Kepler data for asteroseismology of red giants.« less

Cholinergic Plasticity of Oscillating Neuronal Assemblies in Mouse Hippocampal Slices

PubMed Central

Zylla, Maura M.; Zhang, Xiaomin; Reichinnek, Susanne; Draguhn, Andreas; Both, Martin

2013-01-01

The mammalian hippocampus expresses several types of network oscillations which entrain neurons into transiently stable assemblies. These groups of co-active neurons are believed to support the formation, consolidation and recall of context-dependent memories. Formation of new assemblies occurs during theta- and gamma-oscillations under conditions of high cholinergic activity. Memory consolidation is linked to sharp wave-ripple oscillations (SPW-R) during decreased cholinergic tone. We hypothesized that increased cholinergic tone supports plastic changes of assemblies while low cholinergic tone favors their stability. Coherent spatiotemporal network patterns were measured during SPW-R activity in mouse hippocampal slices. We compared neuronal activity within the oscillating assemblies before and after a transient phase of carbachol-induced gamma oscillations. Single units maintained their coupling to SPW-R throughout the experiment and could be re-identified after the transient phase of gamma oscillations. However, the frequency of SPW-R-related unit firing was enhanced after muscarinic stimulation. At the network level, these changes resulted in altered patterns of extracellularly recorded SPW-R waveforms. In contrast, recording of ongoing SPW-R activity without intermittent cholinergic stimulation revealed remarkably stable repetitive activation of assemblies. These results show that activation of cholinergic receptors induces plasticity at the level of oscillating hippocampal assemblies, in line with the different role of gamma- and SPW-R network activity for memory formation and –consolidation, respectively. PMID:24260462

Antiferromagnetic THz-frequency Josephson-like Oscillator Driven by Spin Current.

PubMed

Khymyn, Roman; Lisenkov, Ivan; Tiberkevich, Vasyl; Ivanov, Boris A; Slavin, Andrei

2017-03-06

The development of compact and tunable room temperature sources of coherent THz-frequency signals would open a way for numerous new applications. The existing approaches to THz-frequency generation based on superconductor Josephson junctions (JJ), free electron lasers, and quantum cascades require cryogenic temperatures or/and complex setups, preventing the miniaturization and wide use of these devices. We demonstrate theoretically that a bi-layer of a heavy metal (Pt) and a bi-axial antiferromagnetic (AFM) dielectric (NiO) can be a source of a coherent THz signal. A spin-current flowing from a DC-current-driven Pt layer and polarized along the hard AFM anisotropy axis excites a non-uniform in time precession of magnetizations sublattices in the AFM, due to the presence of a weak easy-plane AFM anisotropy. The frequency of the AFM oscillations varies in the range of 0.1-2.0 THz with the driving current in the Pt layer from 10 8  A/cm 2 to 10 9  A/cm 2 . The THz-frequency signal from the AFM with the amplitude exceeding 1 V/cm is picked up by the inverse spin-Hall effect in Pt. The operation of a room-temperature AFM THz-frequency oscillator is similar to that of a cryogenic JJ oscillator, with the energy of the easy-plane magnetic anisotropy playing the role of the Josephson energy.

Antiferromagnetic THz-frequency Josephson-like Oscillator Driven by Spin Current

NASA Astrophysics Data System (ADS)

Khymyn, Roman; Lisenkov, Ivan; Tiberkevich, Vasyl; Ivanov, Boris A.; Slavin, Andrei

2017-03-01

The development of compact and tunable room temperature sources of coherent THz-frequency signals would open a way for numerous new applications. The existing approaches to THz-frequency generation based on superconductor Josephson junctions (JJ), free electron lasers, and quantum cascades require cryogenic temperatures or/and complex setups, preventing the miniaturization and wide use of these devices. We demonstrate theoretically that a bi-layer of a heavy metal (Pt) and a bi-axial antiferromagnetic (AFM) dielectric (NiO) can be a source of a coherent THz signal. A spin-current flowing from a DC-current-driven Pt layer and polarized along the hard AFM anisotropy axis excites a non-uniform in time precession of magnetizations sublattices in the AFM, due to the presence of a weak easy-plane AFM anisotropy. The frequency of the AFM oscillations varies in the range of 0.1-2.0 THz with the driving current in the Pt layer from 108 A/cm2 to 109 A/cm2. The THz-frequency signal from the AFM with the amplitude exceeding 1 V/cm is picked up by the inverse spin-Hall effect in Pt. The operation of a room-temperature AFM THz-frequency oscillator is similar to that of a cryogenic JJ oscillator, with the energy of the easy-plane magnetic anisotropy playing the role of the Josephson energy.

Temperature and frequency dependence of anelasticity in a nickel oscillator

NASA Astrophysics Data System (ADS)

Berg, Robert F.

1995-09-01

The frequency dependence of the real and imaginary parts of a nickel oscillator's transfer function is described over 3 decades in frequency by the use of simple expressions. These expressions incorporate only the resonance frequency ω0, the quality factor Q, and a characteristic exponent β determined by a single measurement of creep. They are based on the ansatz φ(ω)=Q-1(ω/ω0)-β, where φ is the imaginary part of the spring constant. Over a 100 K range of temperature T, the exponent β≂0.18 was constant even though Q(T) changed by a factor of 8. These expressions are potentially useful for accurately describing a mechanical oscillator whose transfer function must be modeled at frequencies far below ω0. Examples include accelerometers based on a flexure element and suspensions for interferometric gravitational wave detectors.

A one-parametric formula relating the frequencies of twin-peak quasi-periodic oscillations

NASA Astrophysics Data System (ADS)

Török, Gabriel; Goluchová, Kateřina; Šrámková, Eva; Horák, Jiří; Bakala, Pavel; Urbanec, Martin

2017-12-01

Timing analysis of X-ray flux in more than a dozen low-mass X-ray binary systems containing a neutron star reveals remarkable correlations between frequencies of two characteristic peaks present in the power-density spectra. We find a simple analytic relation that well reproduces all these individual correlations. We link this relation to a physical model which involves accretion rate modulation caused by an oscillating torus.

An optimized low-power voltage controlled oscillator

NASA Astrophysics Data System (ADS)

Shah, Kriyang; Le, Hai Phuong; Singh, Jugdutt

2007-01-01

This paper presents an optimised low-power low-phase-noise Voltage Controlled Oscillator (VCO) for Bluetooth wireless applications. The system level design issues and tradeoffs related to Direct Conversion Receiver (DCR) and Low Intermediate Frequency (IF) architecture for Bluetooth are discussed. Subsequently, for a low IF architecture, the critical VCO performance parameters are derived from system specifications. The VCO presented in the paper is optimised by implementing a novel biasing circuit that employs two current mirrors, one at the top and the other one at the bottom of the cross-coupled complementary VCO, to give the exact replica of the current in both the arms of current mirror circuit. This approach, therefore, significantly reduces the system power consumption as well as improves the system performance. Results show that, the VCO consumes only 281μW of power at 2V supply. Its phase noise performance are -115dBc/Hz, -130dBc/Hz and -141dBc/Hz at the offset frequency of 1MHz, 3MHz and 5MHz respectively. Results indicate that 31% reduction in power consumption is achieved as compared to the traditional VCO design. These characteristics make the designed VCO a better candidate for Bluetooth wireless application where power consumption is the major issue.

Emergence of amplitude and oscillation death in identical coupled oscillators.

PubMed

Zou, Wei; Senthilkumar, D V; Duan, Jinqiao; Kurths, Jürgen

2014-09-01

We deduce rigorous conditions for the onset of amplitude death (AD) and oscillation death (OD) in a system of identical coupled paradigmatic Stuart-Landau oscillators. A nonscalar coupling and high frequency are beneficial for the onset of AD. In strong contrast, scalar diffusive coupling and low intrinsic frequency are in favor of the emergence of OD. Our finding contributes to clearly distinguish intrinsic geneses for AD and OD, and further substantially corroborates that AD and OD are indeed two dynamically distinct oscillation quenching phenomena due to distinctly different mechanisms.

Ultra-stable, low phase noise dielectric resonator stabilized oscillators for military and commercial systems

NASA Technical Reports Server (NTRS)

Mizan, Muhammad; Higgins, Thomas; Sturzebecher, Dana

1993-01-01

EPSD has designed, fabricated and tested, ultra-stable, low phase noise microwave dielectric resonator oscillators (DRO's) at S, X, Ku, and K-bands, for potential application to high dynamic range and low radar cross section target detection radar systems. The phase noise and the temperature stability surpass commercially available DROs. Low phase noise signals are critical for CW Doppler radars, at both very close-in and large offset frequencies from the carrier. The oscillators were built without any temperature compensation techniques and exhibited a temperature stability of 25 parts per million (ppm) over an extended temperature range. The oscillators are lightweight, small and low cost compared to BAW & SAW oscillators, and can impact commercial systems such as telecommunications, built-in-test equipment, cellular phone and satellite communications systems. The key to obtaining this performance was a high Q factor resonant structure (RS) and careful circuit design techniques. The high Q RS consists of a dielectric resonator (DR) supported by a low loss spacer inside a metal cavity. The S and the X-band resonant structures demonstrated loaded Q values of 20,300 and 12,700, respectively.

AUTOMATIC FREQUENCY CONTROL SYSTEM

DOEpatents

Hansen, C.F.; Salisbury, J.D.

1961-01-10

A control is described for automatically matching the frequency of a resonant cavity to that of a driving oscillator. The driving oscillator is disconnected from the cavity and a secondary oscillator is actuated in which the cavity is the frequency determining element. A low frequency is mixed with the output of the driving oscillator and the resultant lower and upper sidebands are separately derived. The frequencies of the sidebands are compared with the secondary oscillator frequency. deriving a servo control signal to adjust a tuning element in the cavity and matching the cavity frequency to that of the driving oscillator. The driving oscillator may then be connected to the cavity.

Frequency modulation entrains slow neural oscillations and optimizes human listening behavior

PubMed Central

Henry, Molly J.; Obleser, Jonas

2012-01-01

The human ability to continuously track dynamic environmental stimuli, in particular speech, is proposed to profit from “entrainment” of endogenous neural oscillations, which involves phase reorganization such that “optimal” phase comes into line with temporally expected critical events, resulting in improved processing. The current experiment goes beyond previous work in this domain by addressing two thus far unanswered questions. First, how general is neural entrainment to environmental rhythms: Can neural oscillations be entrained by temporal dynamics of ongoing rhythmic stimuli without abrupt onsets? Second, does neural entrainment optimize performance of the perceptual system: Does human auditory perception benefit from neural phase reorganization? In a human electroencephalography study, listeners detected short gaps distributed uniformly with respect to the phase angle of a 3-Hz frequency-modulated stimulus. Listeners’ ability to detect gaps in the frequency-modulated sound was not uniformly distributed in time, but clustered in certain preferred phases of the modulation. Moreover, the optimal stimulus phase was individually determined by the neural delta oscillation entrained by the stimulus. Finally, delta phase predicted behavior better than stimulus phase or the event-related potential after the gap. This study demonstrates behavioral benefits of phase realignment in response to frequency-modulated auditory stimuli, overall suggesting that frequency fluctuations in natural environmental input provide a pacing signal for endogenous neural oscillations, thereby influencing perceptual processing. PMID:23151506

Stereotyped high-frequency oscillations discriminate seizure onset zones and critical functional cortex in focal epilepsy.

PubMed

Liu, Su; Gurses, Candan; Sha, Zhiyi; Quach, Michael M; Sencer, Altay; Bebek, Nerses; Curry, Daniel J; Prabhu, Sujit; Tummala, Sudhakar; Henry, Thomas R; Ince, Nuri F

2018-01-30

High-frequency oscillations in local field potentials recorded with intracranial EEG are putative biomarkers of seizure onset zones in epileptic brain. However, localized 80-500 Hz oscillations can also be recorded from normal and non-epileptic cerebral structures. When defined only by rate or frequency, physiological high-frequency oscillations are indistinguishable from pathological ones, which limit their application in epilepsy presurgical planning. We hypothesized that pathological high-frequency oscillations occur in a repetitive fashion with a similar waveform morphology that specifically indicates seizure onset zones. We investigated the waveform patterns of automatically detected high-frequency oscillations in 13 epilepsy patients and five control subjects, with an average of 73 subdural and intracerebral electrodes recorded per patient. The repetitive oscillatory waveforms were identified by using a pipeline of unsupervised machine learning techniques and were then correlated with independently clinician-defined seizure onset zones. Consistently in all patients, the stereotypical high-frequency oscillations with the highest degree of waveform similarity were localized within the seizure onset zones only, whereas the channels generating high-frequency oscillations embedded in random waveforms were found in the functional regions independent from the epileptogenic locations. The repetitive waveform pattern was more evident in fast ripples compared to ripples, suggesting a potential association between waveform repetition and the underlying pathological network. Our findings provided a new tool for the interpretation of pathological high-frequency oscillations that can be efficiently applied to distinguish seizure onset zones from functionally important sites, which is a critical step towards the translation of these signature events into valid clinical biomarkers.awx374media15721572971001. © The Author(s) (2018). Published by Oxford University Press on

Effects of aberrant gamma frequency oscillations on prepulse inhibition.

PubMed

Jones, Nigel C; Anderson, Paul; Rind, Gil; Sullivan, Caley; van den Buuse, Maarten; O'Brien, Terence J

2014-10-01

Emerging literature implicates abnormalities in gamma frequency oscillations in the pathophysiology of schizophrenia, with hypofunction of N-methyl-D-aspartate (NMDA) receptors implicated as a key factor. Prepulse inhibition (PPI) is a behavioural measure of sensorimotor gating, which is disrupted in schizophrenia. We studied relationships between ongoing and sensory-evoked gamma oscillations and PPI using pharmacological interventions designed to increase gamma oscillations (ketamine, MK-801); reduce gamma oscillations (LY379268); or disrupt PPI (amphetamine). We predicted that elevating ongoing gamma power would lead to increased 'neural noise' in cortical circuits, dampened sensory-evoked gamma responses and disrupted behaviour. Wistar rats were implanted with EEG recording electrodes. They received ketamine (5 mg/kg), MK-801 (0.16 mg/kg), amphetamine (0.5 mg/kg), LY379268 (3 mg/kg) or vehicle and underwent PPI sessions with concurrent EEG recording. Ketamine and MK-801 increased the power of ongoing gamma oscillations and caused time-matched disruptions of PPI, while amphetamine marginally affected ongoing gamma power. In contrast, LY379268 reduced ongoing gamma power, but had no effect on PPI. The sensory gamma response evoked by the prepulse was reduced following treatment with all psychotomimetics, associating with disruptions in PPI. This was most noticeable following treatment with NMDA receptor antagonists. We found that ketamine and MK-801 increase ongoing gamma power and reduce evoked gamma power, both of which are related to disruptions in sensorimotor gating. This appears to be due to antagonism of NMDA receptors, since amphetamine and LY379268 differentially impacted these outcomes and possess different neuropharmacological substrates. Aberrant gamma frequency oscillations caused by NMDA receptor hypofunction may mediate the sensory processing deficits observed in schizophrenia.

Phase reduction of a limit cycle oscillator perturbed by a strong amplitude-modulated high-frequency force.

PubMed

Pyragas, Kestutis; Novičenko, Viktor

2015-07-01

The phase reduction method for a limit cycle oscillator subjected to a strong amplitude-modulated high-frequency force is developed. An equation for the phase dynamics is derived by introducing a new, effective phase response curve. We show that if the effective phase response curve is everywhere positive (negative), then an entrainment of the oscillator to an envelope frequency is possible only when this frequency is higher (lower) than the natural frequency of the oscillator. Also, by using the Pontryagin maximum principle, we have derived an optimal waveform of the perturbation that ensures an entrainment of the oscillator with minimal power. The theoretical results are demonstrated with the Stuart-Landau oscillator and model neurons.

Coherent Phonon Rabi Oscillations with a High-Frequency Carbon Nanotube Phonon Cavity.

PubMed

Zhu, Dong; Wang, Xin-He; Kong, Wei-Cheng; Deng, Guang-Wei; Wang, Jiang-Tao; Li, Hai-Ou; Cao, Gang; Xiao, Ming; Jiang, Kai-Li; Dai, Xing-Can; Guo, Guang-Can; Nori, Franco; Guo, Guo-Ping

2017-02-08

Phonon-cavity electromechanics allows the manipulation of mechanical oscillations similar to photon-cavity systems. Many advances on this subject have been achieved in various materials. In addition, the coherent phonon transfer (phonon Rabi oscillations) between the phonon cavity mode and another oscillation mode has attracted many interest in nanoscience. Here, we demonstrate coherent phonon transfer in a carbon nanotube phonon-cavity system with two mechanical modes exhibiting strong dynamical coupling. The gate-tunable phonon oscillation modes are manipulated and detected by extending the red-detuned pump idea of photonic cavity electromechanics. The first- and second-order coherent phonon transfers are observed with Rabi frequencies 591 and 125 kHz, respectively. The frequency quality factor product fQ m ∼ 2 × 10 12 Hz achieved here is larger than k B T base /h, which may enable the future realization of Rabi oscillations in the quantum regime.

Highly Stable Wideband Microwave Extraction by Synchronizing Widely Tunable Optoelectronic Oscillator with Optical Frequency Comb

PubMed Central

Hou, D.; Xie, X. P.; Zhang, Y. L.; Wu, J. T.; Chen, Z. Y.; Zhao, J. Y.

2013-01-01

Optical frequency combs (OFCs), based on mode-locked lasers (MLLs), have attracted considerable attention in many fields over recent years. Among the applications of OFCs, one of the most challenging works is the extraction of a highly stable microwave with low phase noise. Many synchronisation schemes have been exploited to synchronise an electronic oscillator with the pulse train from a MLL, helping to extract an ultra-stable microwave. Here, we demonstrate novel wideband microwave extraction from a stable OFC by synchronising a single widely tunable optoelectronic oscillator (OEO) with an OFC at different harmonic frequencies, using an optical phase detection technique. The tunable range of the proposed microwave extraction extends from 2 GHz to 4 GHz, and in a long-term synchronisation experiment over 12 hours, the proposed synchronisation scheme provided a rms timing drift of 18 fs and frequency instabilities at 1.2 × 10−15/1 s and 2.2 × 10−18/10000 s. PMID:24336459

Highly Stable Wideband Microwave Extraction by Synchronizing Widely Tunable Optoelectronic Oscillator with Optical Frequency Comb

NASA Astrophysics Data System (ADS)

Hou, D.; Xie, X. P.; Zhang, Y. L.; Wu, J. T.; Chen, Z. Y.; Zhao, J. Y.

2013-12-01

Optical frequency combs (OFCs), based on mode-locked lasers (MLLs), have attracted considerable attention in many fields over recent years. Among the applications of OFCs, one of the most challenging works is the extraction of a highly stable microwave with low phase noise. Many synchronisation schemes have been exploited to synchronise an electronic oscillator with the pulse train from a MLL, helping to extract an ultra-stable microwave. Here, we demonstrate novel wideband microwave extraction from a stable OFC by synchronising a single widely tunable optoelectronic oscillator (OEO) with an OFC at different harmonic frequencies, using an optical phase detection technique. The tunable range of the proposed microwave extraction extends from 2 GHz to 4 GHz, and in a long-term synchronisation experiment over 12 hours, the proposed synchronisation scheme provided a rms timing drift of 18 fs and frequency instabilities at 1.2 × 10-15/1 s and 2.2 × 10-18/10000 s.

Low-frequency oscillations of the neural drive to the muscle are increased with experimental muscle pain

PubMed Central

Negro, Francesco; Gizzi, Leonardo; Falla, Deborah

2012-01-01

We investigated the influence of nociceptive stimulation on the accuracy of task execution and motor unit spike trains during low-force isometric contractions. Muscle pain was induced by infusion of hypertonic saline into the abductor digiti minimi muscle of 11 healthy men. Intramuscular EMG signals were recorded from the same muscle during four isometric contractions of 60-s duration at 10% of the maximal force [maximal voluntary contraction (MVC)] performed before injection (baseline), after injection of isotonic (control) or hypertonic saline (pain), and 15 min after pain was no longer reported. Each contraction was preceded by three 3-s ramp contractions from 0% to 10% MVC. The low-frequency oscillations of motor unit spike trains were analyzed by the first principal component of the low-pass filtered spike trains [first common component (FCC)], which represents the effective neural drive to the muscle. Pain decreased the accuracy of task performance [coefficient of variation (CoV) for force: baseline, 2.8 ± 1.8%, pain, 3.9 ± 1.8%; P < 0.05] and reduced motor unit discharge rates [11.6 ± 2.3 pulses per second (pps) vs. 10.7 ± 1.7 pps; P < 0.05]. Motor unit recruitment thresholds (2.2 ± 1.2% MVC vs. 2.4 ± 1.6% MVC), interspike interval variability (18.4 ± 4.9% vs. 19.1 ± 5.4%), strength of motor unit short-term synchronization [common input strength (CIS) 1.02 ± 0.44 vs. 0.83 ± 0.22], and strength of common drive (0.47 ± 0.08 vs. 0.47 ± 0.06) did not change across conditions. The FCC signal was correlated with force (R = 0.45 ± 0.06), and the CoV for FCC increased in the painful condition (5.69 ± 1.29% vs. 7.83 ± 2.61%; P < 0.05). These results indicate that nociceptive stimulation increased the low-frequency variability in synaptic input to motoneurons. PMID:22049336

An integrated low phase noise radiation-pressure-driven optomechanical oscillator chipset

PubMed Central

Luan, Xingsheng; Huang, Yongjun; Li, Ying; McMillan, James F.; Zheng, Jiangjun; Huang, Shu-Wei; Hsieh, Pin-Chun; Gu, Tingyi; Wang, Di; Hati, Archita; Howe, David A.; Wen, Guangjun; Yu, Mingbin; Lo, Guoqiang; Kwong, Dim-Lee; Wong, Chee Wei

2014-01-01

High-quality frequency references are the cornerstones in position, navigation and timing applications of both scientific and commercial domains. Optomechanical oscillators, with direct coupling to continuous-wave light and non-material-limited f × Q product, are long regarded as a potential platform for frequency reference in radio-frequency-photonic architectures. However, one major challenge is the compatibility with standard CMOS fabrication processes while maintaining optomechanical high quality performance. Here we demonstrate the monolithic integration of photonic crystal optomechanical oscillators and on-chip high speed Ge detectors based on the silicon CMOS platform. With the generation of both high harmonics (up to 59th order) and subharmonics (down to 1/4), our chipset provides multiple frequency tones for applications in both frequency multipliers and dividers. The phase noise is measured down to −125 dBc/Hz at 10 kHz offset at ~400 μW dropped-in powers, one of the lowest noise optomechanical oscillators to date and in room-temperature and atmospheric non-vacuum operating conditions. These characteristics enable optomechanical oscillators as a frequency reference platform for radio-frequency-photonic information processing. PMID:25354711

Phase locking and multiple oscillating attractors for the coupled mammalian clock and cell cycle

PubMed Central

Feillet, Céline; Krusche, Peter; Tamanini, Filippo; Janssens, Roel C.; Downey, Mike J.; Martin, Patrick; Teboul, Michèle; Saito, Shoko; Lévi, Francis A.; Bretschneider, Till; van der Horst, Gijsbertus T. J.; Delaunay, Franck; Rand, David A.

2014-01-01

Daily synchronous rhythms of cell division at the tissue or organism level are observed in many species and suggest that the circadian clock and cell cycle oscillators are coupled. For mammals, despite known mechanistic interactions, the effect of such coupling on clock and cell cycle progression, and hence its biological relevance, is not understood. In particular, we do not know how the temporal organization of cell division at the single-cell level produces this daily rhythm at the tissue level. Here we use multispectral imaging of single live cells, computational methods, and mathematical modeling to address this question in proliferating mouse fibroblasts. We show that in unsynchronized cells the cell cycle and circadian clock robustly phase lock each other in a 1:1 fashion so that in an expanding cell population the two oscillators oscillate in a synchronized way with a common frequency. Dexamethasone-induced synchronization reveals additional clock states. As well as the low-period phase-locked state there are distinct coexisting states with a significantly higher period clock. Cells transition to these states after dexamethasone synchronization. The temporal coordination of cell division by phase locking to the clock at a single-cell level has significant implications because disordered circadian function is increasingly being linked to the pathogenesis of many diseases, including cancer. PMID:24958884

ELISA: a cryocooled 10 GHz oscillator with 10(-15) frequency stability.

PubMed

Grop, S; Bourgeois, P Y; Bazin, N; Kersalé, Y; Rubiola, E; Langham, C; Oxborrow, M; Clapton, D; Walker, S; De Vicente, J; Giordano, V

2010-02-01

This article reports the design, the breadboarding, and the validation of an ultrastable cryogenic sapphire oscillator operated in an autonomous cryocooler. The objective of this project was to demonstrate the feasibility of a frequency stability of 3x10(-15) between 1 and 1000 s for the European Space Agency deep space stations. This represents the lowest fractional frequency instability ever achieved with cryocoolers. The preliminary results presented in this paper validate the design we adopted for the sapphire resonator, the cold source, and the oscillator loop.

Frequency adjustment and synchrony in networks of delayed pulse-coupled oscillators

NASA Astrophysics Data System (ADS)

Nishimura, Joel

2015-01-01

We introduce a system of pulse-coupled oscillators that can change both their phases and frequencies and prove that when there is a separation of time scales between phase and frequency adjustment the system converges to exact synchrony on strongly connected graphs with time delays. The analysis involves decomposing the network into a forest of tree-like structures that capture causality. These results provide a robust method of sensor net synchronization as well as demonstrate a new avenue of possible pulse-coupled oscillator research.

Preparation of a second station for the measurement of solar oscillations of low degree 'l'

NASA Technical Reports Server (NTRS)

Cacciani, A.; Fabbri, F.; Ricci, D.; Rosati, P.; Marquedant, R.; Smith, E.

1990-01-01

An observing station to detect low-degree global solar oscillations is already operational at the Jet Propulsion Laboratory. A second station for continuative measurements of such oscillations has recently been installed and successfully tested in Rome. The high transmission and stability of the magneto-optical filter (MOF) coupled with the lock-in amplifier technique allow analog and real-time detection of oscillation modes with a noise level of only a few cm/s. Observing runs and estimates of the signal-to-noise ratio are shown in time and frequency domains. Routine observations will establish whether the MOF sensitivity and stability are suitable for the detection of stellar oscillations.

Frequency comb based on a narrowband Yb-fiber oscillator: pre-chirp management for self-referenced carrier envelope offset frequency stabilization.

PubMed

Lim, Jinkang; Chen, Hung-Wen; Chang, Guoqing; Kärtner, Franz X

2013-02-25

Laser frequency combs are normally based on mode-locked oscillators emitting ultrashort pulses of ~100-fs or shorter. In this paper, we present a self-referenced frequency comb based on a narrowband (5-nm bandwidth corresponding to 415-fs transform-limited pulses) Yb-fiber oscillator with a repetition rate of 280 MHz. We employ a nonlinear Yb-fiber amplifier to both amplify the narrowband pulses and broaden their optical spectrum. To optimize the carrier envelope offset frequency (fCEO), we optimize the nonlinear pulse amplification by pre-chirping the pulses at the amplifier input. An optimum negative pre-chirp exists, which produces a signal-to-noise ratio of 35 dB (100 kHz resolution bandwidth) for the detected fCEO. We phase stabilize the fCEO using a feed-forward method, resulting in 0.64-rad (integrated from 1 Hz to 10 MHz) phase noise for the in-loop error signal. This work demonstrates the feasibility of implementing frequency combs from a narrowband oscillator, which is of particular importance for realizing large line-spacing frequency combs based on multi-GHz oscillators usually emitting long (>200 fs) pulses.

Weld pool oscillation during pulsed GTA welding

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aendenroomer, A.J.R.; Ouden, G. den

1996-12-31

This paper deals with weld pool oscillation during pulsed GTA welding and with the possibility to use this oscillation for in-process control of weld penetration. Welding experiments were carried out under different welding conditions. During welding the weld pool was triggered into oscillation by the normal welding pulses or by extra current pulses. The oscillation frequency was measured both during the pulse time and during the base time by analyzing the arc voltage variation using a Fast Fourier Transformation program. Optimal results are obtained when full penetration occurs during the pulse time and partial penetration during the base time. Undermore » these conditions elliptical overlapping spot welds are formed. In the case of full penetration the weld pool oscillates in a low frequency mode (membrane oscillation), whereas in the case of partial penetration the weld pool oscillates in a high frequency mode (surface oscillation). Deviation from the optimal welding conditions occurs when high frequency oscillation is observed during both pulse time and base time (underpenetration) or when low frequency oscillation is observed during both pulse time and base time (overpenetration). In line with these results a penetration sensing system with feedback control was designed, based on the criterion that optimal weld penetration is achieved when two peaks are observed in the frequency distribution. The feasibility of this sensing system for orbital tube welding was confirmed by the results of experiments carried out under various welding conditions.« less

Optically controlled low-power on-off mode resonant tunneling oscillator with a heterojunction phototransistor switch.

PubMed

Lee, Kiwon; Park, Jaehong; Lee, Jooseok; Yang, Kyounghoon

2015-03-15

We report an optically controlled low-power on-off mode oscillator based on a resonant tunneling diode (RTD) that is monolithically integrated with a heterojunction phototransistor (HPT) optical switch. In order to achieve a low-power operation at a wavelength of 1.55 μm an InP-based quantum-effect tunneling diode is used for microwave signal generation based on a unique negative differential conductance (NDC) characteristic of the RTD at a low applied voltage. In addition, the high-gain HPT is used for converting incident optical data to an electrical data signal. The fabricated on-off mode oscillator shows a low-power consumption of 5 mW and a high-data-rate of 1  Gb/s at an oscillation frequency of 4.7 GHz. A good energy efficiency of 5  pJ/bit has been obtained due to the low DC power consumption along with high-data-rate performance of the RTD-based optoelectronic integration scheme.

High-frequency optical oscillation during the flare phase of the red dwarf EV Lac

NASA Astrophysics Data System (ADS)

Contadakis, M.; Avgoloupis, S.; Seiradakis, J.

2006-01-01

The observational support of the presence of high frequency low amplitude oscillations reported by Zhillyaev et al. 2000 and Contadakis et al. 2004, is highly demanding and will be done by the future observations and by carefully reanalysing the data from our files. In this paper we present the results of the analysis of the B-light curve for a flare of magnitude 1.01,which was observed on September,1993. Despite the low time resolution (sampling interval 12s) we were able to detect transient low amplitude oscillations with period ranging between 30s and 125s with a confidence level higher than 70%. This result is in favour of (or does not contradict) the suggested explanation i.e the evolution of a fast mode magneto-acoustic wave generated at the impulsive phase of the flare and travelling through the magnetic loop From: Michael E.Contadakis Address: kodadaki@vergina.eng.auth.gr Database: phy

Parametric Oscillation, Frequency Mixing, and Injection Locking of Strongly Coupled Nanomechanical Resonator Modes.

PubMed

Seitner, Maximilian J; Abdi, Mehdi; Ridolfo, Alessandro; Hartmann, Michael J; Weig, Eva M

2017-06-23

We study locking phenomena of two strongly coupled, high quality factor nanomechanical resonator modes to a common parametric drive at a single drive frequency in different parametric driving regimes. By controlled dielectric gradient forces we tune the resonance frequencies of the flexural in-plane and out-of-plane oscillation of the high stress silicon nitride string through their mutual avoided crossing. For the case of the strong common parametric drive signal-idler generation via nondegenerate parametric two-mode oscillation is observed. Broadband frequency tuning of the very narrow linewidth signal and idler resonances is demonstrated. When the resonance frequencies of the signal and idler get closer to each other, partial injection locking, injection pulling, and complete injection locking to half of the drive frequency occurs depending on the pump strength. Furthermore, satellite resonances, symmetrically offset from the signal and idler by their beat note, are observed, which can be attributed to degenerate four-wave mixing in the highly nonlinear mechanical oscillations.

Forced Longitudinal Oscillations of a Gas in an Open Pipe Near the Resonance Excitation Frequency

NASA Astrophysics Data System (ADS)

Zaripov, R. G.; Tkachenko, L. A.; Shaidullin, L. R.

2017-11-01

Results of theoretical and experimental investigations of forced longitudinal oscillations of a homogeneous gas in an open pipe near the first natural frequency are presented. It has been established that at the resonance frequency the shape of the gas pressure wave changes with time by a law different from the harmonic one. The amplitude-frequency characteristics of the indicated oscillations have been derived. Satisfactory agreement of the theoretical calculation of the gas pressure oscillation range with experimental data has been obtained.

Measurement of ultra-low power oscillators using adaptive drift cancellation with applications to nano-magnetic spin torque oscillators.

PubMed

Tamaru, S; Ricketts, D S

2013-05-01

This work presents a technique for measuring ultra-low power oscillator signals using an adaptive drift cancellation method. We demonstrate this technique through spectrum measurements of a sub-pW nano-magnet spin torque oscillator (STO). We first present a detailed noise analysis of the standard STO characterization apparatus to estimate the background noise level, then compare these results to the noise level of three measurement configurations. The first and second share the standard configuration but use different spectrum analyzers (SA), an older model and a state-of-the-art model, respectively. The third is the technique proposed in this work using the same old SA as for the first. Our results show that the first and second configurations suffer from a large drift that requires ~30 min to stabilize each time the SA changes the frequency band, even though the SA has been powered on for longer than 24 h. The third configuration introduced in this work, however, shows absolutely no drift as the SA changes frequency band, and nearly the same noise performance as with a state-of-the-art SA, thus providing a reliable method for measuring very low power signals for a wide variety of applications.

High-frequency Oscillations in the Atmosphere above a Sunspot Umbra

NASA Astrophysics Data System (ADS)

Wang, Feng; Deng, Hui; Li, Bo; Feng, Song; Bai, Xianyong; Deng, Linhua; Yang, Yunfei; Xue, Zhike; Wang, Rui

2018-03-01

We use high spatial and temporal resolution observations, simultaneously obtained with the New Vacuum Solar Telescope and Atmospheric Imaging Assembly (AIA) on board the Solar Dynamics Observatory, to investigate the high-frequency oscillations above a sunspot umbra. A novel time–frequency analysis method, namely, the synchrosqueezing transform (SST), is employed to represent their power spectra and to reconstruct the high-frequency signals at different solar atmospheric layers. A validation study with synthetic signals demonstrates that SST is capable of resolving weak signals even when their strength is comparable to the high-frequency noise. The power spectra, obtained from both SST and the Fourier transform, of the entire umbral region indicate that there are significant enhancements between 10 and 14 mHz (labeled as 12 mHz) at different atmospheric layers. Analyzing the spectrum of a photospheric region far away from the umbra demonstrates that this 12 mHz component exists only inside the umbra. The animation based on the reconstructed 12 mHz component in AIA 171 Å illustrates that an intermittently propagating wave first emerges near the footpoints of coronal fan structures, and then propagates outward along the structures. A time–distance diagram, coupled with a subsonic wave speed (∼49 km s‑1), highlights the fact that these coronal perturbations are best described as upwardly propagating magnetoacoustic slow waves. Thus, we first reveal the high-frequency oscillations with a period around one minute in imaging observations at different height above an umbra, and these oscillations seem to be related to the umbral perturbations in the photosphere.

Selective Coupling between Theta Phase and Neocortical Fast Gamma Oscillations during REM-Sleep in Mice

PubMed Central

Scheffzük, Claudia; Kukushka, Valeriy I.; Vyssotski, Alexei L.; Draguhn, Andreas

2011-01-01

Background The mammalian brain expresses a wide range of state-dependent network oscillations which vary in frequency and spatial extension. Such rhythms can entrain multiple neurons into coherent patterns of activity, consistent with a role in behaviour, cognition and memory formation. Recent evidence suggests that locally generated fast network oscillations can be systematically aligned to long-range slow oscillations. It is likely that such cross-frequency coupling supports specific tasks including behavioural choice and working memory. Principal Findings We analyzed temporal coupling between high-frequency oscillations and EEG theta activity (4–12 Hz) in recordings from mouse parietal neocortex. Theta was exclusively present during active wakefulness and REM-sleep. Fast oscillations occurred in two separate frequency bands: gamma (40–100 Hz) and fast gamma (120–160 Hz). Theta, gamma and fast gamma were more prominent during active wakefulness as compared to REM-sleep. Coupling between theta and the two types of fast oscillations, however, was more pronounced during REM-sleep. This state-dependent cross-frequency coupling was particularly strong for theta-fast gamma interaction which increased 9-fold during REM as compared to active wakefulness. Theta-gamma coupling increased only by 1.5-fold. Significance State-dependent cross-frequency-coupling provides a new functional characteristic of REM-sleep and establishes a unique property of neocortical fast gamma oscillations. Interactions between defined patterns of slow and fast network oscillations may serve selective functions in sleep-dependent information processing. PMID:22163023

The influence of cochlear shape on low-frequency hearing.

PubMed

Manoussaki, Daphne; Chadwick, Richard S; Ketten, Darlene R; Arruda, Julie; Dimitriadis, Emilios K; O'Malley, Jen T

2008-04-22

The conventional theory about the snail shell shape of the mammalian cochlea is that it evolved essentially and perhaps solely to conserve space inside the skull. Recently, a theory proposed that the spiral's graded curvature enhances the cochlea's mechanical response to low frequencies. This article provides a multispecies analysis of cochlear shape to test this theory and demonstrates that the ratio of the radii of curvature from the outermost and innermost turns of the cochlear spiral is a significant cochlear feature that correlates strongly with low-frequency hearing limits. The ratio, which is a measure of curvature gradient, is a reflection of the ability of cochlear curvature to focus acoustic energy at the outer wall of the cochlear canal as the wave propagates toward the apex of the cochlea.

Low-Power Photothermal Self-Oscillation of Bimetallic Nanowires.

PubMed

De Alba, Roberto; Abhilash, T S; Rand, Richard H; Craighead, Harold G; Parpia, Jeevak M

2017-07-12

We investigate the nonlinear mechanics of a bimetallic, optically absorbing SiN-Nb nanowire in the presence of incident laser light and a reflecting Si mirror. Situated in a standing wave of optical intensity and subject to photothermal forces, the nanowire undergoes self-induced oscillations at low incident light thresholds of <1 μW due to engineered strong temperature-position (T-z) coupling. Along with inducing self-oscillation, laser light causes large changes to the mechanical resonant frequency ω 0 and equilibrium position z 0 that cannot be neglected. We present experimental results and a theoretical model for the motion under laser illumination. In the model, we solve the governing nonlinear differential equations by perturbative means to show that self-oscillation amplitude is set by the competing effects of direct T-z coupling and 2ω 0 parametric excitation due to T-ω 0 coupling. We then study the linearized equations of motion to show that the optimal thermal time constant τ for photothermal feedback is τ → ∞ rather than the previously reported ω 0 τ = 1. Lastly, we demonstrate photothermal quality factor (Q) enhancement of driven motion as a means to counteract air damping. Understanding photothermal effects on nano- and micromechanical devices, as well as nonlinear aspects of optics-based motion detection, can enable new device applications as oscillators or other electronic elements with smaller device footprints and less stringent ambient vacuum requirements.

Multiple circadian transcriptional elements cooperatively regulate cell-autonomous transcriptional oscillation of Period3, a mammalian clock gene.

PubMed

Matsumura, Ritsuko; Akashi, Makoto

2017-09-29

Cell-autonomous oscillation in clock gene expression drives circadian rhythms. The development of comprehensive analytical techniques, such as bioinformatics and ChIP-sequencing, has enabled the genome-wide identification of potential circadian transcriptional elements that regulate the transcriptional oscillation of clock genes. However, detailed analyses using traditional biochemical and molecular-biological approaches, such as binding and reporter assays, are still necessary to determine whether these potential circadian transcriptional elements are actually functional and how significantly they contribute to driving transcriptional oscillation. Here, we focused on the molecular mechanism of transcriptional oscillations in the mammalian clock gene Period3 ( Per3 ). The PER3 protein is essential for robust peripheral clocks and is a key component in circadian output processes. We found three E box-like elements located upstream of human Per3 transcription start sites that additively contributed to cell-autonomous transcriptional oscillation. However, we also found that Per3 is still expressed in a circadian manner when all three E box-like elements are functionally impaired. We noted that Per3 transcription was activated by the synergistic actions of two D box-like elements and the three E box-like elements, leading to a drastic increase in circadian amplitude. Interestingly, circadian expression of Per3 was completely disrupted only when all five transcriptional elements were functionally impaired. These results indicate that three E box-like and two D box-like elements cooperatively and redundantly regulate cell-autonomous transcriptional oscillation of Per3 . © 2017 by The American Society for Biochemistry and Molecular Biology, Inc.

Low phase noise oscillator using two parallel connected amplifiers

NASA Technical Reports Server (NTRS)

Kleinberg, Leonard L.

1987-01-01

A high frequency oscillator is provided by connecting two amplifier circuits in parallel where each amplifier circuit provides the other amplifier circuit with the conditions necessary for oscillation. The inherent noise present in both amplifier circuits causes the quiescent current, and in turn, the generated frequency, to change. The changes in quiescent current cause the transconductance and the load impedance of each amplifier circuit to vary, and this in turn results in opposing changes in the input susceptance of each amplifier circuit. Because the changes in input susceptance oppose each other, the changes in quiescent current also oppose each other. The net result is that frequency stability is enhanced.

Electro-opto-mechanical radio-frequency oscillator driven by guided acoustic waves in standard single-mode fiber

NASA Astrophysics Data System (ADS)

London, Yosef; Diamandi, Hilel Hagai; Zadok, Avi

2017-04-01

An opto-electronic radio-frequency oscillator that is based on forward scattering by the guided acoustic modes of a standard single-mode optical fiber is proposed and demonstrated. An optical pump wave is used to stimulate narrowband, resonant guided acoustic modes, which introduce phase modulation to a co-propagating optical probe wave. The phase modulation is converted to an intensity signal at the output of a Sagnac interferometer loop. The intensity waveform is detected, amplified, and driven back to modulate the optical pump. Oscillations are achieved at a frequency of 319 MHz, which matches the resonance of the acoustic mode that provides the largest phase modulation of the probe wave. Oscillations at the frequencies of competing acoustic modes are suppressed by at least 40 dB. The linewidth of the acoustic resonance is sufficiently narrow to provide oscillations at a single longitudinal mode of the hybrid cavity. Competing longitudinal modes are suppressed by at least 38 dB as well. Unlike other opto-electronic oscillators, no radio-frequency filtering is required within the hybrid cavity. The frequency of oscillations is entirely determined by the fiber opto-mechanics.

System for adjusting frequency of electrical output pulses derived from an oscillator

DOEpatents

Bartholomew, David B.

2006-11-14

A system for setting and adjusting a frequency of electrical output pulses derived from an oscillator in a network is disclosed. The system comprises an accumulator module configured to receive pulses from an oscillator and to output an accumulated value. An adjustor module is configured to store an adjustor value used to correct local oscillator drift. A digital adder adds values from the accumulator module to values stored in the adjustor module and outputs their sums to the accumulator module, where they are stored. The digital adder also outputs an electrical pulse to a logic module. The logic module is in electrical communication with the adjustor module and the network. The logic module may change the value stored in the adjustor module to compensate for local oscillator drift or change the frequency of output pulses. The logic module may also keep time and calculate drift.

Fast Dynamical Coupling Enhances Frequency Adaptation of Oscillators for Robotic Locomotion Control

PubMed Central

Nachstedt, Timo; Tetzlaff, Christian; Manoonpong, Poramate

2017-01-01

Rhythmic neural signals serve as basis of many brain processes, in particular of locomotion control and generation of rhythmic movements. It has been found that specific neural circuits, named central pattern generators (CPGs), are able to autonomously produce such rhythmic activities. In order to tune, shape and coordinate the produced rhythmic activity, CPGs require sensory feedback, i.e., external signals. Nonlinear oscillators are a standard model of CPGs and are used in various robotic applications. A special class of nonlinear oscillators are adaptive frequency oscillators (AFOs). AFOs are able to adapt their frequency toward the frequency of an external periodic signal and to keep this learned frequency once the external signal vanishes. AFOs have been successfully used, for instance, for resonant tuning of robotic locomotion control. However, the choice of parameters for a standard AFO is characterized by a trade-off between the speed of the adaptation and its precision and, additionally, is strongly dependent on the range of frequencies the AFO is confronted with. As a result, AFOs are typically tuned such that they require a comparably long time for their adaptation. To overcome the problem, here, we improve the standard AFO by introducing a novel adaptation mechanism based on dynamical coupling strengths. The dynamical adaptation mechanism enhances both the speed and precision of the frequency adaptation. In contrast to standard AFOs, in this system, the interplay of dynamics on short and long time scales enables fast as well as precise adaptation of the oscillator for a wide range of frequencies. Amongst others, a very natural implementation of this mechanism is in terms of neural networks. The proposed system enables robotic applications which require fast retuning of locomotion control in order to react to environmental changes or conditions. PMID:28377710

Ultrastable Cryogenic Microwave Oscillators

NASA Astrophysics Data System (ADS)

Mann, Anthony G.

Ultrastable cryogenic microwave oscillators are secondary frequency standards in the microwave domain. The best of these oscillators have demonstrated a short term frequency stability in the range 10-14 to a few times 10-16. The main application for these oscillators is as flywheel oscillators for the next generation of passive atomic frequency standards, and as local oscillators in space telemetry ground stations to clean up the transmitter close in phase noise. Fractional frequency stabilities of passive atomic frequency standards are now approaching 3 x10^-14 /τ where τ is the measurement time, limited only by the number of atoms that are being interrogated. This requires an interrogation oscillator whose short-term stability is of the order of 10-14 or better, which cannot be provided by present-day quartz technology. Ultrastable cryogenic microwave oscillators are based on resonators which have very high electrical Q-factors. The resolution of the resonator's linewidth is typically limited by electronics noise to about 1ppm and hence Q-factors in excess of 108 are required. As these are only attained in superconducting cavities or sapphire resonators at low temperatures, use of liquid helium cooling is mandatory, which has so far restricted these oscillators to the research or metrology laboratory. Recently, there has been an effort to dispense with the need for liquid helium and make compact flywheel oscillators for the new generation of primary frequency standards. Work is under way to achieve this goal in space-borne and mobile liquid-nitrogen-cooled systems. The best cryogenic oscillators developed to date are the ``whispering gallery'' (WG) mode sapphire resonator-oscillators of NASA's Jet Propulsion Laboratory (JPL) and the University of Western Australia (UWA), as well as Stanford University's superconducting cavity stabilized oscillator (SCSO). All of these oscillators have demonstrated frequency

Design of a new low-phase-noise millimetre-wave quadrature voltage-controlled oscillator

NASA Astrophysics Data System (ADS)

Kashani, Zeinab; Nabavi, Abdolreza

2018-07-01

This paper presents a new circuit topology of millimetre-wave quadrature voltage-controlled oscillator (QVCO) using an improved Colpitts oscillator without tail bias. By employing an extra capacitance between the drain and source terminations of the transistors and optimising circuit values, a low-power and low-phase-noise (PN) oscillator is designed. For generating the output signals with 90° phase difference, a self-injection coupling network between two identical cores is used. The proposed QVCO dissipates no extra dc power for coupling, since there is no dc-path to ground for the coupled transistors and no extra noise is added to circuit. The best figure-of-merit is -188.5, the power consumption is 14.98-15.45 mW, in a standard 180-nm CMOS technology, for 58.2 GHz center frequency from 59.3 to 59.6 GHz. The PN is -104.86 dBc/Hz at 1-MHz offset.

Pulse-coupled Belousov-Zhabotinsky oscillators with frequency modulation

NASA Astrophysics Data System (ADS)

Horvath, Viktor; Epstein, Irving R.

2018-04-01

Inhibitory perturbations to the ferroin-catalyzed Belousov-Zhabotinsky (BZ) chemical oscillator operated in a continuously fed stirred tank reactor cause long term changes to the limit cycle: the lengths of the cycles subsequent to the perturbation are longer than that of the unperturbed cycle, and the unperturbed limit cycle is recovered only after several cycles. The frequency of the BZ reaction strongly depends on the acid concentration of the medium. By adding strong acid or base to the perturbing solutions, the magnitude and the direction of the frequency changes concomitant to excitatory or inhibitory perturbations can be controlled independently of the coupling strength. The dynamics of two BZ oscillators coupled through perturbations carrying a coupling agent (activator or inhibitor) and a frequency modulator (strong acid or base) was explored using a numerical model of the system. Here, we report new complex temporal patterns: higher order, partially synchronized modes that develop when inhibitory coupling is combined with positive frequency modulation (FM), and complex bursting patterns when excitatory coupling is combined with negative FM. The role of time delay between the peak and perturbation (the analog of synaptic delays in networks of neurons) has also been studied. The complex patterns found under inhibitory coupling and positive FM vanish when the delay is significant, whereas a sufficiently long time delay is required for the complex temporal dynamics to occur when coupling is excitatory and FM is negative.

Quantifying the correlation between photoplethysmography and laser Doppler flowmetry microvascular low-frequency oscillations

NASA Astrophysics Data System (ADS)

Mizeva, Irina; Di Maria, Costanzo; Frick, Peter; Podtaev, Sergey; Allen, John

2015-03-01

Photoplethysmography (PPG) and laser Doppler flowmetry (LDF) are two recognized optical techniques that can track low-frequency perfusion changes in microcirculation. The aim of this study was to determine, in healthy subjects, the correlation between the techniques for specific low-frequency bands previously defined for microcirculation. Twelve healthy male subjects (age range 18 to 50 years) were studied, with PPG and LDF signals recorded for 20 min from their right and left index (PPG) and middle (LDF) fingers. Wavelet analysis comprised dividing the low-frequency integral wavelet spectrum (IWS) into five established physiological bands relating to cardiac, respiratory, myogenic, neurogenic, and endothelial activities. The correlation between PPG and LDF was quantified using wavelet correlation analysis and Spearman correlation analysis of the median IWS amplitude. The median wavelet correlation between signals (right-left side average) was 0.45 (cardiac), 0.49 (respiratory), 0.86 (myogenic), 0.91 (neurogenic), and 0.91 (endothelial). The correlation of IWS amplitude values (right-left side average) was statistically significant for the cardiac (ρ=0.64, p<0.05) and endothelial (ρ=0.62, p<0.05) bands. This pilot study has shown good correlation between PPG and LDF for specific physiological frequency bands. In particular, the results suggest that PPG has the potential to be a low-cost replacement for LDF for endothelial activity assessments.

Frequency spectrum of transepithelial potential difference reveals transport-related oscillations.

PubMed

Montalbetti, Nicolás; Fischbarg, Jorge

2009-09-16

How epithelia transport fluid is a fundamental issue that is unresolved. Explanations offered include molecular engines, local transcellular osmosis, local paracellular osmosis, and paracellular fluid transport. On the basis of experimental and theoretical work done on corneal endothelium, a fluid transporting epithelium, we suggest electroosmotic coupling at the level of the intercellular junctions driven by the transendothelial electrical potential difference as an explanation of paracellular fluid transport. We collect frequency spectra of that potential difference in real-time. For what we believe is the first time for any epithelium, we report that, unexpectedly, the potential difference displays oscillations at many characteristic frequencies. We also show that on both stimulating cell activity and inhibiting ion transport mechanisms, there are corresponding changes in the oscillations amplitudes that mirror changes known previously in rates of fluid transport. We believe these findings provide a novel tool to study the kinetics of electrogenic elements such as channels and transporters, which from this evidence would give rise to current oscillations with characteristic periods going from 150 ms to 8 s.

Unprecedented long-term frequency stability with a microwave resonator oscillator.

PubMed

Grop, Serge; Schafer, Wolfgang; Bourgeois, Pierre-Yves; Kersale, Yann; Oxborrow, Mark; Rubiola, Enrico; Giordano, Vincent

2011-08-01

This article reports on the long-term frequency stability characterization of a new type of cryogenic sapphire oscillator using an autonomous pulse-tube cryocooler as its cold source. This new design enables a relative frequency stability of better than 4.5 x 10(-15) over one day of integration. To the best of our knowledge, this represents the best long-term frequency stability ever obtained with a signal source based on a macroscopic resonator.

Generation of mechanical oscillation applicable to vibratory rate gyroscopes

NASA Technical Reports Server (NTRS)

Lemkin, Mark A. (Inventor); Juneau, Thor N. (Inventor); Clark, William A. (Inventor); Roessig, Allen W. (Inventor)

2001-01-01

To achieve a drive-axis oscillation with improved frequency and amplitude stability, additional feedback loops are used to adjust force-feedback loop parameters. An amplitude-control loop measures oscillation amplitude, compares this value to the desired level, and adjusts damping of the mechanical sense-element to grow or shrink oscillation amplitude as appropriate. A frequency-tuning loop measures the oscillation frequency, compares this value with a highly stable reference, and adjusts the gain in the force-feedback loop to keep the drive-axis oscillation frequency at the reference value. The combined topology simultaneously controls both amplitude and frequency. Advantages of the combined topology include improved stability, fast oscillation start-up, low power consumption, and excellent shock rejection.

Frequency stability degradation of an oscillator slaved to a periodically interrogated atomic resonator.

PubMed

Santarelli, G; Audoin, C; Makdissi, A; Laurent, P; Dick, G J; Clairon, A

1998-01-01

Atomic frequency standards using trapped ions or cold atoms work intrinsically in a pulsed mode. Theoretically and experimentally, this mode of operation has been shown to lead to a degradation of the frequency stability due to the frequency noise of the interrogation oscillator. In this paper a physical analysis of this effect has been made by evaluating the response of a two-level atom to the interrogation oscillator phase noise in Ramsey and multi-Rabi interrogation schemes using a standard quantum mechanical approach. This response is then used to calculate the degradation of the frequency stability of a pulsed atomic frequency standard such as an atomic fountain or an ion trap standard. Comparison is made to an experimental evaluation of this effect in the LPTF Cs fountain frequency standard, showing excellent agreement.

Cholinergic enhancement of visual attention and neural oscillations in the human brain.

PubMed

Bauer, Markus; Kluge, Christian; Bach, Dominik; Bradbury, David; Heinze, Hans Jochen; Dolan, Raymond J; Driver, Jon

2012-03-06

Cognitive processes such as visual perception and selective attention induce specific patterns of brain oscillations. The neurochemical bases of these spectral changes in neural activity are largely unknown, but neuromodulators are thought to regulate processing. The cholinergic system is linked to attentional function in vivo, whereas separate in vitro studies show that cholinergic agonists induce high-frequency oscillations in slice preparations. This has led to theoretical proposals that cholinergic enhancement of visual attention might operate via gamma oscillations in visual cortex, although low-frequency alpha/beta modulation may also play a key role. Here we used MEG to record cortical oscillations in the context of administration of a cholinergic agonist (physostigmine) during a spatial visual attention task in humans. This cholinergic agonist enhanced spatial attention effects on low-frequency alpha/beta oscillations in visual cortex, an effect correlating with a drug-induced speeding of performance. By contrast, the cholinergic agonist did not alter high-frequency gamma oscillations in visual cortex. Thus, our findings show that cholinergic neuromodulation enhances attentional selection via an impact on oscillatory synchrony in visual cortex, for low rather than high frequencies. We discuss this dissociation between high- and low-frequency oscillations in relation to proposals that lower-frequency oscillations are generated by feedback pathways within visual cortex. Copyright © 2012 Elsevier Ltd. All rights reserved.

KvN mechanics approach to the time-dependent frequency harmonic oscillator.

PubMed

Ramos-Prieto, Irán; Urzúa-Pineda, Alejandro R; Soto-Eguibar, Francisco; Moya-Cessa, Héctor M

2018-05-30

Using the Ermakov-Lewis invariants appearing in KvN mechanics, the time-dependent frequency harmonic oscillator is studied. The analysis builds upon the operational dynamical model, from which it is possible to infer quantum or classical dynamics; thus, the mathematical structure governing the evolution will be the same in both cases. The Liouville operator associated with the time-dependent frequency harmonic oscillator can be transformed using an Ermakov-Lewis invariant, which is also time dependent and commutes with itself at any time. Finally, because the solution of the Ermakov equation is involved in the evolution of the classical state vector, we explore some analytical and numerical solutions.

High-frequency sediment-level oscillations in the swash zone

USGS Publications Warehouse

Sallenger, A.H.; Richmond, B.M.

1984-01-01

Sediment-level oscillations with heights of about 6 cm and shore-normal lengths of order 10 m have been measured in the swash zone of a high-energy, coarse-sand beach. Crests of oscillations were shore parallel and continuous alongshore. The oscillations were of such low steepness (height-to-length ratio approximately 0.006) that they were difficult to detect visually. The period of oscillation ranged between 6 and 15 min and decreased landward across the swash zone. The sediment-level oscillations were progressive landward with an average migration rate in the middle to upper swash zone of 0.8 m min-1. Migration was caused mostly by erosion on the seaward flank of the crest of an oscillation during a period of net seaward sediment transport. Thus, the observed migration was a form migration landward rather than a migration involving net landward sediment transport. The observed sediment-level oscillations were different than sand waves or other swash-zone bedforms previously described. ?? 1984.

Short Meditation Trainings Enhance Non-REM Sleep Low-Frequency Oscillations.

PubMed

Dentico, Daniela; Ferrarelli, Fabio; Riedner, Brady A; Smith, Richard; Zennig, Corinna; Lutz, Antoine; Tononi, Giulio; Davidson, Richard J

2016-01-01

We have recently shown higher parietal-occipital EEG gamma activity during sleep in long-term meditators compared to meditation-naive individuals. This gamma increase was specific for NREM sleep, was present throughout the entire night and correlated with meditation expertise, thus suggesting underlying long-lasting neuroplastic changes induced through prolonged training. The aim of this study was to explore the neuroplastic changes acutely induced by 2 intensive days of different meditation practices in the same group of practitioners. We also repeated baseline recordings in a meditation-naive cohort to account for time effects on sleep EEG activity. High-density EEG recordings of human brain activity were acquired over the course of whole sleep nights following intervention. Sound-attenuated sleep research room. Twenty-four long-term meditators and twenty-four meditation-naïve controls. Two 8-h sessions of either a mindfulness-based meditation or a form of meditation designed to cultivate compassion and loving kindness, hereafter referred to as compassion meditation. We found an increase in EEG low-frequency oscillatory activities (1-12 Hz, centered around 7-8 Hz) over prefrontal and left parietal electrodes across whole night NREM cycles. This power increase peaked early in the night and extended during the third cycle to high-frequencies up to the gamma range (25-40 Hz). There was no difference in sleep EEG activity between meditation styles in long-term meditators nor in the meditation naïve group across different time points. Furthermore, the prefrontal-parietal changes were dependent on meditation life experience. This low-frequency prefrontal-parietal activation likely reflects acute, meditation-related plastic changes occurring during wakefulness, and may underlie a top-down regulation from frontal and anterior parietal areas to the posterior parietal and occipital regions showing chronic, long-lasting plastic changes in long-term meditators.

Abnormal functional integration of thalamic low frequency oscillation in the BOLD signal after acute heroin treatment.

PubMed

Denier, Niklaus; Schmidt, André; Gerber, Hana; Vogel, Marc; Huber, Christian G; Lang, Undine E; Riecher-Rossler, Anita; Wiesbeck, Gerhard A; Radue, Ernst-Wilhelm; Walter, Marc; Borgwardt, Stefan

2015-12-01

Heroin addiction is a severe relapsing brain disorder associated with impaired cognitive control, including deficits in attention allocation. The thalamus has a high density of opiate receptors and is critically involved in orchestrating cortical activity during cognitive control. However, there have been no studies on how acute heroin treatment modulates thalamic activity. In a cross-over, double-blind, vehicle-controlled study, 29 heroin-maintained outpatients were studied after heroin and placebo administration, while 20 healthy controls were included for the placebo condition only. Resting-state functional magnetic resonance imaging was used to analyze functional integration of the thalamus by three different resting state analysis techniques. Thalamocortical functional connectivity (FC) was analyzed by seed-based correlation, while intrinsic thalamic oscillation was assessed by analysis of regional homogeneity (ReHo) and the fractional amplitude of low frequency fluctuations (fALFF). Relative to the placebo treatment and healthy controls, acute heroin administration reduced thalamocortical FC to cortical regions, including the frontal cortex, while the reductions in FC to the mediofrontal cortex, orbitofrontal cortex, and frontal pole were positively correlated with the plasma level of morphine, the main psychoactive metabolite of heroin. Furthermore, heroin treatment was associated with increased thalamic ReHo and fALFF values, whereas fALFF following heroin exposure correlated negatively with scores of attentional control. The heroin-associated increase in fALFF was mainly dominated by slow-4 (0.027-0.073 Hz) oscillations. Our findings show that there are acute effects of heroin within the thalamocortical system and may shed new light on the role of the thalamus in cognitive control in heroin addiction. Future research is needed to determine the underlying physiological mechanisms and their role in heroin addiction. © 2015 Wiley Periodicals, Inc.

Qubit dephasing due to low-frequency noise.

NASA Astrophysics Data System (ADS)

Sverdlov, Victor; Rabenstein, Kristian; Averin, Dmitri

2004-03-01

We have numerically investigated the effects of the classical low-frequency noise on the qubit dynamics beyond the standard lowest-order perturbation theory in coupling. Noise is generated as a random process with a correlation function characterized by two parameters, the amplitude v0 and the cut-off frequency 2π/τ. Time evolution of the density matrix was averaged over up to 10^7 noise realizations. Contrary to the relaxation time T_1, which for v_0<ω, where ω is the qubit oscillation frequency, is always given correctly by the ``golden-rule'' expression, the dephasing time deviates from the perturbation-theory result, when (v_0/ω)^2(ωτ) ≥1. In this regime, even for unbiased qubit for which the pure dephasing vanishes in perturbation theory, the dephasing is much larger than it's perturbation-theory value 1/(2 T_1).

Spontaneous Oscillation by Hair Bundles of the Bullfrog's Sacculus

PubMed Central

Martin, Pascal; Bozovic, D.; Choe, Y.; Hudspeth, A. J.

2007-01-01

One prominent manifestation of mechanical activity in hair cells is spontaneous otoacoustic emission, the unprovoked emanation of sound by an internal ear. Because active hair-bundle motility probably constitutes the active process of non-mammalian hair cells, we investigated the ability of hair bundles in the bullfrog's sacculus to produce oscillations that might underlie spontaneous otoacoustic emissions. When maintained in the ear's normal ionic milieu, many bundles oscillated spontaneously through distances as great as 80 nm at frequencies of 5-50 Hz. Whole-cell recording disclosed that the positive phase of movement was associated with the opening of transduction channels. Gentamicin, which blocks transduction channels, reversibly arrested oscillation; drugs that affect the cAMP phosphorylation pathway and might influence myosin's activity altered the rate of oscillation. Increasing the Ca2+ concentration rendered oscillations faster and smaller until they were suppressed; lowering the Ca2+ concentration moderately with chelators had the opposite effect. When a bundle was offset with a stimulus fiber, oscillations were transiently suppressed but gradually resumed. Loading a bundle by partial displacement clamping, which simulated the presence of the accessory structures to which a bundle is ordinarily attached, increased the frequency and diminished the magnitude of oscillation. These observations accord with a model in which oscillations arise from the interplay of the hair bundle's negative stiffness with the activity of adaptation motors and with Ca2+-dependent relaxation of gating springs. PMID:12805294

Measurement of high-degree solar oscillation frequencies

NASA Technical Reports Server (NTRS)

Bachmann, K. T.; Duvall, T. L., Jr.; Harvey, J. W.; Hill, F.

1995-01-01

We present m-averaged solar p- and f-mode oscillation frequencies over the frequency range nu greater than 1.8 and less than 5.0 mHz and the spherical harmonic degree range l greater than or equal to 100 and less than or equal to 1200 from full-disk, 1000 x 1024 pixel, Ca II intensity images collected 1993 June 22-25 with a temporal cadence of 60 s. We itemize the sources and magnitudes of statistical and systematic uncertainties and of small frequency corrections, and we show that our frequencies represent an improvement in accuracy and coverage over previous measurements. Our frequencies agree at the 2 micro Hz level with Mount Wilson frequencies determined for l less than or equal to 600 from full-disk images, and we find systematic offsets of 10-20 micro Hz with respect to frequencies measured from Big Bear and La Palma observations. We give evidence that these latter offsets are indicative of spatial scaling uncertainties associated with the analysis of partial-disk images. In comparison with theory, our p-mode frequencies agree within 10 micro Hz of frequencies predicted by the Los Alamos model but are as much as 100 micro Hz smaller than frequencies predicted by the Denmark and Yale models at degrees near 1000. We also find systematic differences between our n = 0 frequencies and the frequencies closely agreed upon by all three models.

Integrated optoelectronic oscillator.

PubMed

Tang, Jian; Hao, Tengfei; Li, Wei; Domenech, David; Baños, Rocio; Muñoz, Pascual; Zhu, Ninghua; Capmany, José; Li, Ming

2018-04-30

With the rapid development of the modern communication systems, radar and wireless services, microwave signal with high-frequency, high-spectral-purity and frequency tunability as well as microwave generator with light weight, compact size, power-efficient and low cost are increasingly demanded. Integrated microwave photonics (IMWP) is regarded as a prospective way to meet these demands by hybridizing the microwave circuits and the photonics circuits on chip. In this article, we propose and experimentally demonstrate an integrated optoelectronic oscillator (IOEO). All of the devices needed in the optoelectronic oscillation loop circuit are monolithically integrated on chip within size of 5×6cm 2 . By tuning the injection current to 44 mA, the output frequency of the proposed IOEO is located at 7.30 GHz with phase noise value of -91 dBc/Hz@1MHz. When the injection current is increased to 65 mA, the output frequency can be changed to 8.87 GHz with phase noise value of -92 dBc/Hz@1MHz. Both of the oscillation frequency can be slightly tuned within 20 MHz around the center oscillation frequency by tuning the injection current. The method about improving the performance of IOEO is carefully discussed at the end of in this article.

Dynamics of multi-frequency oscillator ensembles with resonant coupling

NASA Astrophysics Data System (ADS)

Lück, S.; Pikovsky, A.

2011-07-01

We study dynamics of populations of resonantly coupled oscillators having different frequencies. Starting from the coupled van der Pol equations we derive the Kuramoto-type phase model for the situation, where the natural frequencies of two interacting subpopulations are in relation 2:1. Depending on the parameter of coupling, ensembles can demonstrate fully synchronous clusters, partial synchrony (only one subpopulation synchronizes), or asynchrony in both subpopulations. Theoretical description of the dynamics based on the Watanabe-Strogatz approach is developed.

Information coding with frequency of oscillations in Belousov-Zhabotinsky encapsulated disks

NASA Astrophysics Data System (ADS)

Gorecki, J.; Gorecka, J. N.; Adamatzky, Andrew

2014-04-01

Information processing with an excitable chemical medium, like the Belousov-Zhabotinsky (BZ) reaction, is typically based on information coding in the presence or absence of excitation pulses. Here we present a new concept of Boolean coding that can be applied to an oscillatory medium. A medium represents the logical TRUE state if a selected region oscillates with a high frequency. If the frequency fails below a specified value, it represents the logical FALSE state. We consider a medium composed of disks encapsulating an oscillatory mixture of reagents, as related to our recent experiments with lipid-coated BZ droplets. We demonstrate that by using specific geometrical arrangements of disks containing the oscillatory medium one can perform logical operations on variables coded in oscillation frequency. Realizations of a chemical signal diode and of a single-bit memory with oscillatory disks are also discussed.

Internal Fluid Dynamics and Frequency Scaling of Sweeping Jet Fluidic Oscillators

NASA Astrophysics Data System (ADS)

Seo, Jung Hee; Salazar, Erik; Mittal, Rajat

2017-11-01

Sweeping jet fluidic oscillators (SJFOs) are devices that produce a spatially oscillating jet solely based on intrinsic flow instability mechanisms without any moving parts. Recently, SJFOs have emerged as effective actuators for flow control, but the internal fluid dynamics of the device that drives the oscillatory flow mechanism is not yet fully understood. In the current study, the internal fluid dynamics of the fluidic oscillator with feedback channels has been investigated by employing incompressible flow simulations. The study is focused on the oscillation mechanisms and scaling laws that underpin the jet oscillation. Based on the simulation results, simple phenomenological models that connect the jet deflection to the feedback flow are developed. Several geometric modifications are considered in order to explore the characteristic length scales and phase relationships associated with the jet oscillation and to assess the proposed phenomenological model. A scaling law for the jet oscillation frequency is proposed based on the detailed analysis. This research is supported by AFOSR Grant FA9550-14-1-0289 monitored by Dr. Douglas Smith.

Disordered high-frequency oscillation in face processing in schizophrenia patients

PubMed Central

Liu, Miaomiao; Pei, Guangying; Peng, Yinuo; Wang, Changming; Yan, Tianyi; Wu, Jinglong

2018-01-01

Abstract Schizophrenia is a complex disorder characterized by marked social dysfunctions, but the neural mechanism underlying this deficit is unknown. To investigate whether face-specific perceptual processes are influenced in schizophrenia patients, both face detection and configural analysis were assessed in normal individuals and schizophrenia patients by recording electroencephalogram (EEG) data. Here, a face processing model was built based on the frequency oscillations, and the evoked power (theta, alpha, and beta bands) and the induced power (gamma bands) were recorded while the subjects passively viewed face and nonface images presented in upright and inverted orientations. The healthy adults showed a significant face-specific effect in the alpha, beta, and gamma bands, and an inversion effect was observed in the gamma band in the occipital lobe and right temporal lobe. Importantly, the schizophrenia patients showed face-specific deficits in the low-frequency beta and gamma bands, and the face inversion effect in the gamma band was absent from the occipital lobe. All these results revealed face-specific processing in patients due to the disorder of high-frequency EEG, providing additional evidence to enrich future studies investigating neural mechanisms and serving as a marked diagnostic basis. PMID:29419668

Numerical simulation of the transition to chaos in a dissipative Duffing oscillator with two-frequency excitation

NASA Astrophysics Data System (ADS)

Zavrazhina, T. V.

2007-10-01

A mathematical modeling technique is proposed for oscillation chaotization in an essentially nonlinear dissipative Duffing oscillator with two-frequency excitation on an invariant torus in ℝ2. The technique is based on the joint application of the parameter continuation method, Floquet stability criteria, bifurcation theory, and the Everhart high-accuracy numerical integration method. This approach is used for the numerical construction of subharmonic solutions in the case when the oscillator passes to chaos through a sequence of period-multiplying bifurcations. The value of a universal constant obtained earlier by the author while investigating oscillation chaotization in dissipative oscillators with single-frequency periodic excitation is confirmed.

Low Frequency (11 mHz) Oscillations in H1743-322: A New Class of Black Hole QPOs?

NASA Technical Reports Server (NTRS)

Altamirano, D.; Strohmayer, T.

2012-01-01

We report the discovery of quasi-periodic oscillations (QPO) at approx 11 mHz in two RXTE observations and one Chandra observation of the black hole candidate HI743-322. The QPO is observed only at the beginning of the 2010 and 2011 outbursts at similar hard color and intensity, suggestive of an accretion state dependence for the QPO. Although its frequency appears to be correlated with Xray intensity on timescales of a day, in successive outbursts eight months apart we measure a QPO frequency that differs by less than approximately equals 0.0015 Hz while the intensity had changed significantly. We show that this 11 mHz QPO is different from the so-called Type-C QPOs seen in black holes and that the mechanisms that produce the two flavors of variability are most probably independent. We compare the 11 mHz QPO with other variability phenomena seen in accreting black holes and neutron stars and conclude that although at 1-2 orders of magnitude lower in frequency, they best resemble the so-called "1 Hz" QPOs seen in dipping neutron star systems. If confirmed, H1743-322 is the first black hole showing this type of variability. Given the unusual characteristics and the hard-state dependence of the 11 mHz QPO, we speculate that these oscillations might instead be related to the radio jets observed in HI743-322. It remains unexplained, however, why similar QPOs have not yet been identified in other black holes and why they have only been seen in the last two outbursts of HI743-322.

Direct measurement of density oscillation induced by a radio-frequency wave.

PubMed

Yamada, T; Ejiri, A; Shimada, Y; Oosako, T; Tsujimura, J; Takase, Y; Kasahara, H

2007-08-01

An O-mode reflectometer at a frequency of 25.85 GHz was applied to plasmas heated by the high harmonic fast wave (21 MHz) in the TST-2 spherical tokamak. An oscillation in the phase of the reflected microwave in the rf range was observed directly for the first time. In TST-2, the rf (250 kW) induced density oscillation depends mainly on the poloidal rf electric field, which is estimated to be about 0.2 kV/m rms by the reflectometer measurement. Sideband peaks separated in frequency by ion cyclotron harmonics from 21 MHz, and peaks at ion cyclotron harmonics which are suggested to be quasimodes generated by parametric decay, were detected.

Frequency Regulation and Oscillation Damping Contributions of Variable-Speed Wind Generators in the U.S. Eastern Interconnection (EI)

DOE PAGES

Liu, Yong; Gracia, Jose R,; King, Jr, Thomas J.; ...

2014-05-16

The U.S. Eastern Interconnection (EI) is one of the largest electric power grids in the world and is expected to have difficulties in dealing with frequency regulation and oscillation damping issues caused by the increasing wind power. On the other side, variable-speed wind generators can actively engage in frequency regulation or oscillation damping with supplementary control loops. This paper creates a 5% wind power penetration simulation scenario based on the 16 000-bus EI system dynamic model and developed the user-defined wind electrical control model in PSS (R) E that incorporates additional frequency regulation and oscillation damping control loops. We evaluatedmore » the potential contributions of variable-speed wind generations to the EI system frequency regulation and oscillation damping, and simulation results demonstrate that current and future penetrations of wind power are promising in the EI system frequency regulation and oscillation damping.« less

Input-dependent frequency modulation of cortical gamma oscillations shapes spatial synchronization and enables phase coding.

PubMed

Lowet, Eric; Roberts, Mark; Hadjipapas, Avgis; Peter, Alina; van der Eerden, Jan; De Weerd, Peter

2015-02-01

Fine-scale temporal organization of cortical activity in the gamma range (∼25-80Hz) may play a significant role in information processing, for example by neural grouping ('binding') and phase coding. Recent experimental studies have shown that the precise frequency of gamma oscillations varies with input drive (e.g. visual contrast) and that it can differ among nearby cortical locations. This has challenged theories assuming widespread gamma synchronization at a fixed common frequency. In the present study, we investigated which principles govern gamma synchronization in the presence of input-dependent frequency modulations and whether they are detrimental for meaningful input-dependent gamma-mediated temporal organization. To this aim, we constructed a biophysically realistic excitatory-inhibitory network able to express different oscillation frequencies at nearby spatial locations. Similarly to cortical networks, the model was topographically organized with spatially local connectivity and spatially-varying input drive. We analyzed gamma synchronization with respect to phase-locking, phase-relations and frequency differences, and quantified the stimulus-related information represented by gamma phase and frequency. By stepwise simplification of our models, we found that the gamma-mediated temporal organization could be reduced to basic synchronization principles of weakly coupled oscillators, where input drive determines the intrinsic (natural) frequency of oscillators. The gamma phase-locking, the precise phase relation and the emergent (measurable) frequencies were determined by two principal factors: the detuning (intrinsic frequency difference, i.e. local input difference) and the coupling strength. In addition to frequency coding, gamma phase contained complementary stimulus information. Crucially, the phase code reflected input differences, but not the absolute input level. This property of relative input-to-phase conversion, contrasting with latency codes

Input-Dependent Frequency Modulation of Cortical Gamma Oscillations Shapes Spatial Synchronization and Enables Phase Coding

PubMed Central

Lowet, Eric; Roberts, Mark; Hadjipapas, Avgis; Peter, Alina; van der Eerden, Jan; De Weerd, Peter

2015-01-01

Fine-scale temporal organization of cortical activity in the gamma range (∼25–80Hz) may play a significant role in information processing, for example by neural grouping (‘binding’) and phase coding. Recent experimental studies have shown that the precise frequency of gamma oscillations varies with input drive (e.g. visual contrast) and that it can differ among nearby cortical locations. This has challenged theories assuming widespread gamma synchronization at a fixed common frequency. In the present study, we investigated which principles govern gamma synchronization in the presence of input-dependent frequency modulations and whether they are detrimental for meaningful input-dependent gamma-mediated temporal organization. To this aim, we constructed a biophysically realistic excitatory-inhibitory network able to express different oscillation frequencies at nearby spatial locations. Similarly to cortical networks, the model was topographically organized with spatially local connectivity and spatially-varying input drive. We analyzed gamma synchronization with respect to phase-locking, phase-relations and frequency differences, and quantified the stimulus-related information represented by gamma phase and frequency. By stepwise simplification of our models, we found that the gamma-mediated temporal organization could be reduced to basic synchronization principles of weakly coupled oscillators, where input drive determines the intrinsic (natural) frequency of oscillators. The gamma phase-locking, the precise phase relation and the emergent (measurable) frequencies were determined by two principal factors: the detuning (intrinsic frequency difference, i.e. local input difference) and the coupling strength. In addition to frequency coding, gamma phase contained complementary stimulus information. Crucially, the phase code reflected input differences, but not the absolute input level. This property of relative input-to-phase conversion, contrasting with latency

Mammalian spontaneous otoacoustic emissions are amplitude-stabilized cochlear standing waves.

PubMed

Shera, Christopher A

2003-07-01

Mammalian spontaneous otoacoustic emissions (SOAEs) have been suggested to arise by three different mechanisms. The local-oscillator model, dating back to the work of Thomas Gold, supposes that SOAEs arise through the local, autonomous oscillation of some cellular constituent of the organ of Corti (e.g., the "active process" underlying the cochlear amplifier). Two other models, by contrast, both suppose that SOAEs are a global collective phenomenon--cochlear standing waves created by multiple internal reflection--but differ on the nature of the proposed power source: Whereas the "passive" standing-wave model supposes that SOAEs are biological noise, passively amplified by cochlear standing-wave resonances acting as narrow-band nonlinear filters, the "active" standing-wave model supposes that standing-wave amplitudes are actively maintained by coherent wave amplification within the cochlea. Quantitative tests of key predictions that distinguish the local-oscillator and global standing-wave models are presented and shown to support the global standing-wave model. In addition to predicting the existence of multiple emissions with a characteristic minimum frequency spacing, the global standing-wave model accurately predicts the mean value of this spacing, its standard deviation, and its power-law dependence on SOAE frequency. Furthermore, the global standing-wave model accounts for the magnitude, sign, and frequency dependence of changes in SOAE frequency that result from modulations in middle-ear stiffness. Although some of these SOAE characteristics may be replicable through artful ad hoc adjustment of local-oscillator models, they all arise quite naturally in the standing-wave framework. Finally, the statistics of SOAE time waveforms demonstrate that SOAEs are coherent, amplitude-stabilized signals, as predicted by the active standing-wave model. Taken together, the results imply that SOAEs are amplitude-stabilized standing waves produced by the cochlea acting as a

Deep-UV sensors based on SAW oscillators using low-temperature-grown AlN films on sapphires.

PubMed

Laksana, Chipta; Chen, Meei-Ru; Liang, Yen; Tzou, An-Jyeg; Kao, Hui-Ling; Jeng, Erik; Chen, Jyh; Chen, Hou-Guang; Jian, Sheng-Rui

2011-08-01

High-quality epitaxial AlN films were deposited on sapphire substrates at low growth temperature using a helicon sputtering system. SAW filters fabricated on the AlN films exhibited excellent characteristics, with center frequency of 354.2 MHz, which corresponds to a phase velocity of 5667 m/s. An oscillator fabricated using AlN-based SAW devices is presented and applied to deep-UV light detection. A frequency downshift of about 43 KHz was observed when the surface of SAW device was illuminated by a UV source with dominant wavelength of around 200 nm. The results indicate the feasibility of developing remote sensors for deep-UV measurement using AlN-based SAW oscillators.

Attention-Induced Deactivations in Very Low Frequency EEG Oscillations: Differential Localisation According to ADHD Symptom Status

PubMed Central

Broyd, Samantha J.; Helps, Suzannah K.; Sonuga-Barke, Edmund J. S.

2011-01-01

Background The default-mode network (DMN) is characterised by coherent very low frequency (VLF) brain oscillations. The cognitive significance of this VLF profile remains unclear, partly because of the temporally constrained nature of the blood oxygen-level dependent (BOLD) signal. Previously we have identified a VLF EEG network of scalp locations that shares many features of the DMN. Here we explore the intracranial sources of VLF EEG and examine their overlap with the DMN in adults with high and low ADHD ratings. Methodology/Principal Findings DC-EEG was recorded using an equidistant 66 channel electrode montage in 25 adult participants with high- and 25 participants with low-ratings of ADHD symptoms during a rest condition and an attention demanding Eriksen task. VLF EEG power was calculated in the VLF band (0.02 to 0.2 Hz) for the rest and task condition and compared for high and low ADHD participants. sLORETA was used to identify brain sources associated with the attention-induced deactivation of VLF EEG power, and to examine these sources in relation to ADHD symptoms. There was significant deactivation of VLF EEG power between the rest and task condition for the whole sample. Using s-LORETA the sources of this deactivation were localised to medial prefrontal regions, posterior cingulate cortex/precuneus and temporal regions. However, deactivation sources were different for high and low ADHD groups: In the low ADHD group attention-induced VLF EEG deactivation was most significant in medial prefrontal regions while for the high ADHD group this deactivation was predominantly localised to the temporal lobes. Conclusions/Significance Attention-induced VLF EEG deactivations have intracranial sources that appear to overlap with those of the DMN. Furthermore, these seem to be related to ADHD symptom status, with high ADHD adults failing to significantly deactivate medial prefrontal regions while at the same time showing significant attenuation of VLF EEG power in

Frequency comb generation in a continuously pumped optical parametric oscillator

NASA Astrophysics Data System (ADS)

Mosca, S.; Parisi, M.; Ricciardi, I.; Leo, F.; Hansson, T.; Erkintalo, M.; Maddaloni, P.; De Natale, P.; Wabnitz, S.; De Rosa, M.

2018-02-01

We demonstrate optical frequency comb generation in a continuously pumped optical parametric oscillator, in the parametric region around half of the pump frequency. We also model the dynamics of such quadratic combs using a single time-domain mean-field equation, and obtain simulation results that are in good agreement with experimentally observed spectra. Moreover, we numerically investigate the coherence properties of simulated combs, showing the existence of correlated and phase-locked combs. Our work could pave the way for a new class of frequency comb sources, which may enable straightforward access to new spectral regions and stimulate novel applications of frequency combs.

Phase and frequency structure of superradiance pulses generated by relativistic Ka-band backward-wave oscillator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rostov, V. V.; Romanchenko, I. V.; Elchaninov, A. A.

2016-08-15

Phase and frequency stability of electromagnetic oscillations in sub-gigawatt superradiance (SR) pulses generated by an extensive slow-wave structure of a relativistic Ka-band backward-wave oscillator were experimentally investigated. Data on the frequency tuning and radiation phase stability of SR pulses with a variation of the energy and current of electron beam were obtained.

Short Meditation Trainings Enhance Non-REM Sleep Low-Frequency Oscillations

PubMed Central

Dentico, Daniela; Ferrarelli, Fabio; Riedner, Brady A.; Smith, Richard; Zennig, Corinna; Lutz, Antoine; Tononi, Giulio; Davidson, Richard J.

2016-01-01

Study Objectives We have recently shown higher parietal-occipital EEG gamma activity during sleep in long-term meditators compared to meditation-naive individuals. This gamma increase was specific for NREM sleep, was present throughout the entire night and correlated with meditation expertise, thus suggesting underlying long-lasting neuroplastic changes induced through prolonged training. The aim of this study was to explore the neuroplastic changes acutely induced by 2 intensive days of different meditation practices in the same group of practitioners. We also repeated baseline recordings in a meditation-naive cohort to account for time effects on sleep EEG activity. Design High-density EEG recordings of human brain activity were acquired over the course of whole sleep nights following intervention. Setting Sound-attenuated sleep research room. Patients or Participants Twenty-four long-term meditators and twenty-four meditation-naïve controls. Interventions Two 8-h sessions of either a mindfulness-based meditation or a form of meditation designed to cultivate compassion and loving kindness, hereafter referred to as compassion meditation. Measurements and Results We found an increase in EEG low-frequency oscillatory activities (1–12 Hz, centered around 7–8 Hz) over prefrontal and left parietal electrodes across whole night NREM cycles. This power increase peaked early in the night and extended during the third cycle to high-frequencies up to the gamma range (25–40 Hz). There was no difference in sleep EEG activity between meditation styles in long-term meditators nor in the meditation naïve group across different time points. Furthermore, the prefrontal-parietal changes were dependent on meditation life experience. Conclusions This low-frequency prefrontal-parietal activation likely reflects acute, meditation-related plastic changes occurring during wakefulness, and may underlie a top-down regulation from frontal and anterior parietal areas to the posterior

Cannabinoid Receptors Mediate Methamphetamine Induction of High Frequency Gamma Oscillations in the Nucleus Accumbens

PubMed Central

Morra, Joshua T.; Glick, Stanley D.; Cheer, Joseph F.

2012-01-01

Patients suffering from amphetamine---induced psychosis display repetitive behaviors, partially alleviated by antipsychotics, which are reminiscent of rodent stereotypies. Due to recent evidence implicating endocannabinoid involvement in brain disorders, including psychosis, we studied the effects of endocannabinoid signaling on neuronal oscillations of rats exhibiting methamphetamine stereotypy. Neuronal network oscillations were recorded with multiple single electrode arrays aimed at the nucleus accumbens of freely moving rats. During the experiments, animals were dosed intravenously with the CB1 receptor antagonist rimonabant (0.3 mg/kg) or vehicle followed by an ascending dose regimen of methamphetamine (0.01, 0.1, 1, and 3 mg/kg; cumulative dosing). The effects of drug administration on stereotypy and local gamma oscillations were evaluated. Methamphetamine treatment significantly increased high frequency gamma oscillations (~ 80 Hz). Entrainment of a subpopulation of nucleus accumbens neurons to high frequency gamma was associated with stereotypy encoding in putative fast-spiking interneurons, but not in putative medium spiny neurons. The observed ability of methamphetamine to induce both stereotypy and high frequency gamma power was potently disrupted following CB1 receptor blockade. The present data suggest that CB1 receptor-dependent mechanisms are recruited by methamphetamine to modify striatal interneuron oscillations that accompany changes in psychomotor state, further supporting the link between endocannabinoids and schizophrenia spectrum disorders. PMID:22609048

Fast oscillations in cortical-striatal networks switch frequency following rewarding events and stimulant drugs.

PubMed

Berke, J D

2009-09-01

Oscillations may organize communication between components of large-scale brain networks. Although gamma-band oscillations have been repeatedly observed in cortical-basal ganglia circuits, their functional roles are not yet clear. Here I show that, in behaving rats, distinct frequencies of ventral striatal local field potential oscillations show coherence with different cortical inputs. The approximately 50 Hz gamma oscillations that normally predominate in awake ventral striatum are coherent with piriform cortex, whereas approximately 80-100 Hz high-gamma oscillations are coherent with frontal cortex. Within striatum, entrainment to gamma rhythms is selective to fast-spiking interneurons, with distinct fast-spiking interneuron populations entrained to different gamma frequencies. Administration of the psychomotor stimulant amphetamine or the dopamine agonist apomorphine causes a prolonged decrease in approximately 50 Hz power and increase in approximately 80-100 Hz power. The same frequency switch is observed for shorter epochs spontaneously in awake, undrugged animals and is consistently provoked for < 1 s following reward receipt. Individual striatal neurons can participate in these brief high-gamma bursts with, or without, substantial changes in firing rate. Switching between discrete oscillatory states may allow different modes of information processing during decision-making and reinforcement-based learning, and may also be an important systems-level process by which stimulant drugs affect cognition and behavior.

High-Frequency Network Oscillations in Cerebellar Cortex

PubMed Central

Middleton, Steven J.; Racca, Claudia; Cunningham, Mark O.; Traub, Roger D.; Monyer, Hannah; Knöpfel, Thomas; Schofield, Ian S.; Jenkins, Alistair; Whittington, Miles A.

2016-01-01

SUMMARY Both cerebellum and neocortex receive input from the somatosensory system. Interaction between these regions has been proposed to underpin the correct selection and execution of motor commands, but it is not clear how such interactions occur. In neocortex, inputs give rise to population rhythms, providing a spatiotemporal coding strategy for inputs and consequent outputs. Here, we show that similar patterns of rhythm generation occur in cerebellum during nicotinic receptor subtype activation. Both gamma oscillations (30–80 Hz) and very fast oscillations (VFOs, 80–160 Hz) were generated by intrinsic cerebellar cortical circuitry in the absence of functional glutamatergic connections. As in neocortex, gamma rhythms were dependent on GABAA receptor-mediated inhibition, whereas VFOs required only nonsynaptically connected intercellular networks. The ability of cerebellar cortex to generate population rhythms within the same frequency bands as neocortex suggests that they act as a common spatiotemporal code within which corticocerebellar dialog may occur. PMID:18549787

RF Frequency Oscillations in the Early Stages of Vacuum Arc Collapse

NASA Technical Reports Server (NTRS)

Griffin, Steven T.; Thio, Y. C. Francis

2003-01-01

RF frequency oscillations may be produced in a typical capacitive charging / discharging pulsed power system. These oscillations may be benign, parasitic, destructive or crucial to energy deposition. In some applications, proper damping of oscillations may be critical to proper plasma formation. Because the energy deposited into the plasma is a function of plasma and circuit conditions, the entire plasma / circuit system needs to be considered as a unit To accomplish this, the initiation of plasma is modeled as a time-varying, non-linear element in a circuit analysis model. The predicted spectra are compared to empirical power density spectra including those obtained from vacuum arcs.

Vertical amplitude phase structure of a low-frequency acoustic field in shallow water

NASA Astrophysics Data System (ADS)

Kuznetsov, G. N.; Lebedev, O. V.; Stepanov, A. N.

2016-11-01

We obtain in integral and analytic form the relations for calculating the amplitude and phase characteristics of an interference structure of orthogonal projections of the oscillation velocity vector in shallow water. For different frequencies and receiver depths, we numerically study the source depth dependences of the effective phase velocities of an equivalent plane wave, the orthogonal projections of the sound pressure phase gradient, and the projections of the oscillation velocity vector. We establish that at low frequencies in zones of interference maxima, independently of source depth, weakly varying effective phase velocity values are observed, which exceed the sound velocity in water by 5-12%. We show that the angles of arrival of the equivalent plane wave and the oscillation velocity vector in the general case differ; however, they virtually coincide in the zone of the interference maximum of the sound pressure under the condition that the horizontal projections of the oscillation velocity appreciably exceed the value of the vertical projection. We give recommendations on using the sound field characteristics in zones with maximum values for solving rangefinding and signal-detection problems.

Suitability of surface acoustic wave oscillators fabricated using low temperature-grown AlN films on GaN/sapphire as UV sensors.

PubMed

Chen, Tzu Chieh; Lin, Yueh Ting; Lin, Chung Yi; Chen, W C; Chen, Meei Ru; Kao, Hui-Ling; Chyi, J I; Hsu, C H

2008-02-01

Epitaxial AlN films were prepared on GaN/sapphire using a helicon sputtering system at the low temperature of 300 degrees C. Surface acoustic wave (SAW) devices fabricated on AlN/GaN/sapphire exhibited superior characteristics compared with those made on GaN/sapphire. An oscillator using an AlN/GaN/sapphirebased SAW device is presented. The oscillation frequency decreased when the device was illuminated by ultraviolet (UV) radiation, and the downshift of the oscillation frequency increased with the illuminating UV power density. The results showed that the AlN/GaN/sapphire-layered structure SAW oscillators are suitable for visible blind UV detection and opened up the feasibility of developing remote UV sensors for different ranges of wavelengths on the III-nitrides.

Opto-electronic microwave oscillator

NASA Astrophysics Data System (ADS)

Yao, X. Steve; Maleki, Lute

1996-12-01

Photonic applications are important in RF communication systems to enhance many functions including remote transfer of antenna signals, carrier frequency up or down conversion, antenna beam steering, and signal filtering. Many of these functions require reference frequency oscillators. However, traditional microwave oscillators cannot meet all the requirements of photonic communication systems that need high frequency and low phase noise signal generation. Because photonic systems involve signals in both optical and electrical domains, an ideal signal source should be able to provide electrical and optical signals. In addition, it should be possible to synchronize or control the signal source by both electrical and optical means. We present such a source1-2 that converts continuous light energy into stable and spectrally pure microwave signals. This Opto-Electronic Oscillator, OEO, consists of a pump laser and a feedback circuit including an intensity modulator, an optical fiber delay line, a photodetector, an amplifier, and a filter, as shown in Figure 1a. Its oscillation frequency, limited only by the speed of the modulator, can be up to 75 GHz.

Metastability and Inter-Band Frequency Modulation in Networks of Oscillating Spiking Neuron Populations

PubMed Central

Bhowmik, David; Shanahan, Murray

2013-01-01

Groups of neurons firing synchronously are hypothesized to underlie many cognitive functions such as attention, associative learning, memory, and sensory selection. Recent theories suggest that transient periods of synchronization and desynchronization provide a mechanism for dynamically integrating and forming coalitions of functionally related neural areas, and that at these times conditions are optimal for information transfer. Oscillating neural populations display a great amount of spectral complexity, with several rhythms temporally coexisting in different structures and interacting with each other. This paper explores inter-band frequency modulation between neural oscillators using models of quadratic integrate-and-fire neurons and Hodgkin-Huxley neurons. We vary the structural connectivity in a network of neural oscillators, assess the spectral complexity, and correlate the inter-band frequency modulation. We contrast this correlation against measures of metastable coalition entropy and synchrony. Our results show that oscillations in different neural populations modulate each other so as to change frequency, and that the interaction of these fluctuating frequencies in the network as a whole is able to drive different neural populations towards episodes of synchrony. Further to this, we locate an area in the connectivity space in which the system directs itself in this way so as to explore a large repertoire of synchronous coalitions. We suggest that such dynamics facilitate versatile exploration, integration, and communication between functionally related neural areas, and thereby supports sophisticated cognitive processing in the brain. PMID:23614040

Single frequency 1083nm ytterbium doped fiber master oscillator power amplifier laser.

PubMed

Huang, Shenghong; Qin, Guanshi; Shirakawa, Akira; Musha, Mitsuru; Ueda, Ken-Ichi

2005-09-05

Single frequency 1083nm ytterbium fiber master oscillator power amplifier system was demonstrated. The oscillator was a linear fiber cavity with loop mirror filter and polarization controller. The loop mirror with unpumped ytterbium fiber as a narrow bandwidth filter discriminated and selected laser longitudinal modes efficiently. Spatial hole burning effect was restrained by adjusting polarization controller appropriately in the linear cavity. The amplifier was 5 m ytterbium doped fiber pumped by 976nm pigtail coupled laser diode. The linewidth of the single frequency laser was about 2 KHz. Output power up to 177 mW was produced under the launched pump power of 332 mW.

Measurement of the Bs0-Bs0 oscillation frequency.

PubMed

Abulencia, A; Acosta, D; Adelman, J; Affolder, T; Akimoto, T; Albrow, M G; Ambrose, D; Amerio, S; Amidei, D; Anastassov, A; Anikeev, K; Annovi, A; Antos, J; Aoki, M; Apollinari, G; Arguin, J-F; Arisawa, T; Artikov, A; Ashmanskas, W; Attal, A; Azfar, F; Azzi-Bacchetta, P; Azzurri, P; Bacchetta, N; Bachacou, H; Badgett, W; Barbaro-Galtieri, A; Barnes, V E; Barnett, B A; Baroiant, S; Bartsch, V; Bauer, G; Bedeschi, F; Behari, S; Belforte, S; Bellettini, G; Bellinger, J; Belloni, A; Ben Haim, E; Benjamin, D; Beretvas, A; Beringer, J; Berry, T; Bhatti, A; Binkley, M; Bisello, D; Blair, R E; Blocker, C; Blumenfeld, B; Bocci, A; Bodek, A; Boisvert, V; Bolla, G; Bolshov, A; Bortoletto, D; Boudreau, J; Boveia, A; Brau, B; Bromberg, C; Brubaker, E; Budagov, J; Budd, H S; Budd, S; Burkett, K; Busetto, G; Bussey, P; Byrum, K L; Cabrera, S; Campanelli, M; Campbell, M; Canelli, F; Canepa, A; Carlsmith, D; Carosi, R; Carron, S; Casal, B; Casarsa, M; Castro, A; Catastini, P; Cauz, D; Cavalli-Sforza, M; Cerri, A; Cerrito, L; Chang, S H; Chapman, J; Chen, Y C; Chertok, M; Chiarelli, G; Chlachidze, G; Chlebana, F; Cho, I; Cho, K; Chokheli, D; Chou, J P; Chu, P H; Chuang, S H; Chung, K; Chung, W H; Chung, Y S; Ciljak, M; Ciobanu, C I; Ciocci, M A; Clark, A; Clark, D; Coca, M; Compostella, G; Convery, M E; Conway, J; Cooper, B; Copic, K; Cordelli, M; Cortiana, G; Crescioli, F; Cruz, A; Cuenca Almenar, C; Cuevas, J; Culbertson, R; Cyr, D; DaRonco, S; D'Auria, S; D'Onofrio, M; Dagenhart, D; de Barbaro, P; De Cecco, S; Deisher, A; De Lentdecker, G; Dell'Orso, M; Delli Paoli, F; Demers, S; Demortier, L; Deng, J; Deninno, M; De Pedis, D; Derwent, P F; Di Giovanni, G P; Di Ruzza, B; Dionisi, C; Dittmann, J R; DiTuro, P; Dörr, C; Donati, S; Donega, M; Dong, P; Donini, J; Dorigo, T; Dube, S; Ebina, K; Efron, J; Ehlers, J; Erbacher, R; Errede, D; Errede, S; Eusebi, R; Fang, H C; Farrington, S; Fedorko, I; Fedorko, W T; Feild, R G; Feindt, M; Fernandez, J P; Field, R; Flanagan, G; Flores-Castillo, L R; Foland, A; Forrester, S; Foster, G W; Franklin, M; Freeman, J C; Frisch, H J; Furic, I; Gallinaro, M; Galyardt, J; Garcia, J E; Garcia Sciveres, M; Garfinkel, A F; Gay, C; Gerberich, H; Gerdes, D; Giagu, S; Giannetti, P; Gibson, A; Gibson, K; Ginsburg, C; Giokaris, N; Giolo, K; Giordani, M; Giromini, P; Giunta, M; Giurgiu, G; Glagolev, V; Glenzinski, D; Gold, M; Goldschmidt, N; Goldstein, J; Gomez, G; Gomez-Ceballos, G; Goncharov, M; González, O; Gorelov, I; Goshaw, A T; Gotra, Y; Goulianos, K; Gresele, A; Griffiths, M; Grinstein, S; Grosso-Pilcher, C; Group, R C; Grundler, U; Guimaraes da Costa, J; Gunay-Unalan, Z; Haber, C; Hahn, S R; Hahn, K; Halkiadakis, E; Hamilton, A; Han, B-Y; Han, J Y; Handler, R; Happacher, F; Hara, K; Hare, M; Harper, S; Harr, R F; Harris, R M; Hatakeyama, K; Hauser, J; Hays, C; Heijboer, A; Heinemann, B; Heinrich, J; Herndon, M; Hidas, D; Hill, C S; Hirschbuehl, D; Hocker, A; Holloway, A; Hou, S; Houlden, M; Hsu, S-C; Huffman, B T; Hughes, R E; Huston, J; Incandela, J; Introzzi, G; Iori, M; Ishizawa, Y; Ivanov, A; Iyutin, B; James, E; Jang, D; Jayatilaka, B; Jeans, D; Jensen, H; Jeon, E J; Jindariani, S; Jones, M; Joo, K K; Jun, S Y; Junk, T R; Kamon, T; Kang, J; Karchin, P E; Kato, Y; Kemp, Y; Kephart, R; Kerzel, U; Khotilovich, V; Kilminster, B; Kim, D H; Kim, H S; Kim, J E; Kim, M J; Kim, S B; Kim, S H; Kim, Y K; Kirsch, L; Klimenko, S; Klute, M; Knuteson, B; Ko, B R; Kobayashi, H; Kondo, K; Kong, D J; Konigsberg, J; Korytov, A; Kotwal, A V; Kovalev, A; Kraan, A; Kraus, J; Kravchenko, I; Kreps, M; Kroll, J; Krumnack, N; Kruse, M; Krutelyov, V; Kuhlmann, S E; Kusakabe, Y; Kwang, S; Laasanen, A T; Lai, S; Lami, S; Lammel, S; Lancaster, M; Lander, R L; Lannon, K; Lath, A; Latino, G; Lazzizzera, I; LeCompte, T; Lee, J; Lee, J; Lee, Y J; Lee, S W; Lefèvre, R; Leonardo, N; Leone, S; Levy, S; Lewis, J D; Lin, C; Lin, C S; Lindgren, M; Lipeles, E; Liss, T M; Lister, A; Litvintsev, D O; Liu, T; Lockyer, N S; Loginov, A; Loreti, M; Loverre, P; Lu, R-S; Lucchesi, D; Lujan, P; Lukens, P; Lungu, G; Lyons, L; Lys, J; Lysak, R; Lytken, E; Mack, P; MacQueen, D; Madrak, R; Maeshima, K; Maki, T; Maksimovic, P; Malde, S; Manca, G; Margaroli, F; Marginean, R; Marino, C; Martin, A; Martin, V; Martínez, M; Maruyama, T; Mastrandrea, P; Matsunaga, H; Mattson, M E; Mazini, R; Mazzanti, P; McFarland, K S; McIntyre, P; McNulty, R; Mehta, A; Menzemer, S; Menzione, A; Merkel, P; Mesropian, C; Messina, A; von der Mey, M; Miao, T; Miladinovic, N; Miles, J; Miller, R; Miller, J S; Mills, C; Milnik, M; Miquel, R; Mitra, A; Mitselmakher, G; Miyamoto, A; Moggi, N; Mohr, B; Moore, R; Morello, M; Movilla Fernandez, P; Mülmenstädt, J; Mukherjee, A; Muller, Th; Mumford, R; Murat, P; Nachtman, J; Naganoma, J; Nahn, S; Nakano, I; Napier, A; Naumov, D; Necula, V; Neu, C; Neubauer, M S; Nielsen, J; Nigmanov, T; Nodulman, L; Norniella, O; Nurse, E; Ogawa, T; Oh, S H; Oh, Y D; Okusawa, T; Oldeman, R; Orava, R; Osterberg, K; Pagliarone, C; Palencia, E; Paoletti, R; Papadimitriou, V; Paramonov, A A; Parks, B; Pashapour, S; Patrick, J; Pauletta, G; Paulini, M; Paus, C; Pellett, D E; Penzo, A; Phillips, T J; Piacentino, G; Piedra, J; Pinera, L; Pitts, K; Plager, C; Pondrom, L; Portell, X; Poukhov, O; Pounder, N; Prakoshyn, F; Pronko, A; Proudfoot, J; Ptohos, F; Punzi, G; Pursley, J; Rademacker, J; Rahaman, A; Rakitin, A; Rappoccio, S; Ratnikov, F; Reisert, B; Rekovic, V; van Remortel, N; Renton, P; Rescigno, M; Richter, S; Rimondi, F; Ristori, L; Robertson, W J; Robson, A; Rodrigo, T; Rogers, E; Rolli, S; Roser, R; Rossi, M; Rossin, R; Rott, C; Ruiz, A; Russ, J; Rusu, V; Saarikko, H; Sabik, S; Safonov, A; Sakumoto, W K; Salamanna, G; Saltó, O; Saltzberg, D; Sanchez, C; Santi, L; Sarkar, S; Sartori, L; Sato, K; Savard, P; Savoy-Navarro, A; Scheidle, T; Schlabach, P; Schmidt, E E; Schmidt, M P; Schmitt, M; Schwarz, T; Scodellaro, L; Scott, A L; Scribano, A; Scuri, F; Sedov, A; Seidel, S; Seiya, Y; Semenov, A; Sexton-Kennedy, L; Sfiligoi, I; Shapiro, M D; Shears, T; Shepard, P F; Sherman, D; Shimojima, M; Shochet, M; Shon, Y; Shreyber, I; Sidoti, A; Sinervo, P; Sisakyan, A; Sjolin, J; Skiba, A; Slaughter, A J; Sliwa, K; Smith, J R; Snider, F D; Snihur, R; Soderberg, M; Soha, A; Somalwar, S; Sorin, V; Spalding, J; Spezziga, M; Spinella, F; Spreitzer, T; Squillacioti, P; Stanitzki, M; Staveris-Polykalas, A; St Denis, R; Stelzer, B; Stelzer-Chilton, O; Stentz, D; Strologas, J; Stuart, D; Suh, J S; Sukhanov, A; Sumorok, K; Sun, H; Suzuki, T; Taffard, A; Takashima, R; Takeuchi, Y; Takikawa, K; Tanaka, M; Tanaka, R; Tanimoto, N; Tecchio, M; Teng, P K; Terashi, K; Tether, S; Thom, J; Thompson, A S; Thomson, E; Tipton, P; Tiwari, V; Tkaczyk, S; Toback, D; Tokar, S; Tollefson, K; Tomura, T; Tonelli, D; Tönnesmann, M; Torre, S; Torretta, D; Tourneur, S; Trischuk, W; Tsuchiya, R; Tsuno, S; Turini, N; Ukegawa, F; Unverhau, T; Uozumi, S; Usynin, D; Vaiciulis, A; Vallecorsa, S; Varganov, A; Vataga, E; Velev, G; Veramendi, G; Veszpremi, V; Vidal, R; Vila, I; Vilar, R; Vine, T; Vollrath, I; Volobouev, I; Volpi, G; Würthwein, F; Wagner, P; Wagner, R G; Wagner, R L; Wagner, W; Wallny, R; Walter, T; Wan, Z; Wang, S M; Warburton, A; Waschke, S; Waters, D; Wester, W C; Whitehouse, B; Whiteson, D; Wicklund, A B; Wicklund, E; Williams, G; Williams, H H; Wilson, P; Winer, B L; Wittich, P; Wolbers, S; Wolfe, C; Wright, T; Wu, X; Wynne, S M; Yagil, A; Yamamoto, K; Yamaoka, J; Yamashita, T; Yang, C; Yang, U K; Yang, Y C; Yao, W M; Yeh, G P; Yoh, J; Yorita, K; Yoshida, T; Yu, G B; Yu, I; Yu, S S; Yun, J C; Zanello, L; Zanetti, A; Zaw, I; Zetti, F; Zhang, X; Zhou, J; Zucchelli, S

2006-08-11

We present the first precise measurement of the Bs0-Bs0 oscillation frequency Deltams. We use 1 fb-1 of data from pp collisions at sqrts=1.96 TeV collected with the CDF II detector at the Fermilab Tevatron. The sample contains signals of 3600 fully reconstructed hadronic Bs decays and 37,000 partially reconstructed semileptonic Bs decays. We measure the probability as a function of proper decay time that the Bs decays with the same, or opposite, flavor as the flavor at production, and we find a signal consistent with Bs0-Bs0 oscillations. The probability that random fluctuations could produce a comparable signal is 0.2%. Under the hypothesis that the signal is due to Bs0-Bs0 oscillations, we measure Deltams=17.31(-0.18)+0.33(stat)+/-0.07(syst) ps-1 and determine |Vtd/Vts|=0.208(-0.002)+0.001(expt)-0.006(+0.008)(theor).

Serotonergic hallucinogens differentially modify gamma and high frequency oscillations in the rat nucleus accumbens.

PubMed

Goda, Sailaja A; Piasecka, Joanna; Olszewski, Maciej; Kasicki, Stefan; Hunt, Mark J

2013-07-01

The nucleus accumbens (NAc) is a site critical for the actions of many drugs of abuse. Psychoactive compounds, such as N-methyl-D-aspartate receptor (NMDAR) antagonists, modify gamma (40-90) and high frequency oscillations (HFO, 130-180 Hz) in local field potentials (LFPs) recorded in the NAc. Lysergic acid diethylamide (LSD) and 2,5-dimethoxy-4-iodoamphetamine (DOI) are serotonergic hallucinogens and activation of 5HT2A receptors likely underlies their hallucinogenic effects. Whether these compounds can also modulate LFP oscillations in the NAc is unclear. This study aims to examine the effect of serotonergic hallucinogens on gamma and HFO recorded in the NAc and to test whether 5HT2A receptors mediate the effects observed. LFPs were recorded from the NAc of freely moving rats. Drugs were administered intraperitoneally. LSD (0.03-0.3 mg/kg) and DOI (0.5-2.0 mg/kg) increased the power and reduced the frequency of HFO. In contrast, the hallucinogens produced a robust reduction in the power of low (40-60 Hz), but not high gamma oscillations (70-90 Hz). MDL 11939 (1.0 mg/kg), a 5HT2A receptor antagonist, fully reversed the changes induced by DOI on HFO but only partially for the low gamma band. Equivalent increases in HFO power were observed after TCB-2 (5HT2A receptor agonist, 0.1-1.5 mg/kg), but not CP 809101 (5H2C receptor agonist, 0.1-3 mg/kg). Notably, hallucinogen-induced increases in HFO power were smaller than those produced by ketamine (25 mg/kg). Serotonergic hallucinogen-induced changes in HFO and gamma are mediated, at least in part, by stimulation of 5HT2A receptors. Comparison of the oscillatory changes produced by serotonergic hallucinogens and NMDAR antagonists are also discussed.

Detection of frequency-mode-shift during thermoacoustic combustion oscillations in a staged aircraft engine model combustor

NASA Astrophysics Data System (ADS)

Kobayashi, Hiroaki; Gotoda, Hiroshi; Tachibana, Shigeru; Yoshida, Seiji

2017-12-01

We conduct an experimental study using time series analysis based on symbolic dynamics to detect a precursor of frequency-mode-shift during thermoacoustic combustion oscillations in a staged aircraft engine model combustor. With increasing amount of the main fuel, a significant shift in the dominant frequency-mode occurs in noisy periodic dynamics, leading to a notable increase in oscillation amplitudes. The sustainment of noisy periodic dynamics during thermoacoustic combustion oscillations is clearly shown by the multiscale complexity-entropy causality plane in terms of statistical complexity. A modified version of the permutation entropy allows us to detect a precursor of the frequency-mode-shift before the amplification of pressure fluctuations.

The Intrinsic Electrophysiological Properties of Mammalian Neurons: Insights into Central Nervous System Function

NASA Astrophysics Data System (ADS)

Llinas, Rodolfo R.

1988-12-01

This article reviews the electroresponsive properties of single neurons in the mammalian central nervous system (CNS). In some of these cells the ionic conductances responsible for their excitability also endow them with autorhythmic electrical oscillatory properties. Chemical or electrical synaptic contacts between these neurons often result in network oscillations. In such networks, autorhytmic neurons may act as true oscillators (as pacemakers) or as resonators (responding preferentially to certain firing frequencies). Oscillations and resonance in the CNS are proposed to have diverse functional roles, such as (i) determining global functional states (for example, sleep-wakefulness or attention), (ii) timing in motor coordination, and (iii) specifying connectivity during development. Also, oscillation, especially in the thalamo-cortical circuits, may be related to certain neurological and psychiatric disorders. This review proposes that the autorhythmic electrical properties of central neurons and their connectivity form the basis for an intrinsic functional coordinate system that provides internal context to sensory input.

UHF FM receiver having improved frequency stability and low RFI emission

DOEpatents

Lupinetti, Francesco

1990-02-27

A UHF receiver which converts UHF modulated carrier signals to baseband video signals without any heterodyne or frequency conversion stages. A bandpass filter having a fixed frequency first filters the signals. A low noise amplifier amplifies the filtered signal and applies the signal through further amplification stages to a limited FM demodulator circuit. The UHF signal is directly converted to a baseband video signal. The baseband video signal is clamped by a clamping circuit before driving a monitor. Frequency stability for the receivers is at a theoretical maximum, and interference to adjacent receivers is eliminated due to the absence of a local oscillator.

Mobilization of colloidal particles by low-frequency dynamic stress stimulation.

PubMed

Beckham, Richard E; Abdel-Fattah, Amr I; Roberts, Peter M; Ibrahim, Reem; Tarimala, Sowmitri

2010-01-05

Naturally occurring seismic events and artificially generated low-frequency (1 to 500 Hz) elastic waves have been observed to alter the production rates of oil and water wells, sometimes increasing and sometimes decreasing production, and to influence the turbidity of surface and well water. The decreases in production are of particular concern, especially when artificially generated elastic waves are applied as a method for enhanced oil recovery. The exact conditions that result in a decrease in production remain unknown. Although the underlying environment is certainly complex, the observed increase in water well turbidity after natural seismic events suggests the existence of a mechanism that can affect both the subsurface flow paths and the mobilization of in situ colloidal particles. This article explores the macroscopic and microscopic effects of low-frequency dynamic stress stimulations on the release of colloidal particles from an analog core representing an infinitesimal section along the propagation paths of an elastic wave. Experiments on a column packed with 1 mm borosilicate beads and loaded with polystyrene microparticles demonstrate that axial mechanical stress oscillations enhance the mobilization of captured microparticles. Increasing the amplitude of the oscillations increases the number of microparticles released and can also result in cyclical spikes in effluent microparticle concentration during stimulation. Under a prolonged period of stimulation, the cyclical effluent spikes coincided with fluctuations in the column pressure data and continued at a diminished level after stimulation. This behavior can be attributed to rearrangements of the beads in the column, resulting in possible changes in the void space and/or tortuosity of the packing. Optical microscopy observations of the beads during low-frequency oscillations reveal that individual beads rotate, thereby rubbing against each other and scraping away portions of the adsorbed

Frequency quenching of microwave-induced resistance oscillations in a high-mobility two-dimensional electron gas

NASA Astrophysics Data System (ADS)

Studenikin, S. A.; Sachrajda, A. S.; Gupta, J. A.; Wasilewski, Z. R.; Fedorych, O. M.; Byszewski, M.; Maude, D. K.; Potemski, M.; Hilke, M.; West, K. W.; Pfeiffer, L. N.

2007-10-01

The frequency dependence of microwave-induced resistance oscillations (MIROs) has been studied experimentally in high-mobility electron GaAs/AlGaAs structures to explore the limits at which these oscillations can be observed. It is found that in dc transport experiments at frequencies above 120GHz , MIROs start to quench, while above 230GHz , they completely disappear. The results will need to be understood theoretically but are qualitatively discussed within a model in which forced electronic charge oscillations (plasmons) play an intermediate role in the interaction process between the radiation and the single-particle electron excitations between Landau levels.

Coherent frequency division with a degenerate synchronously pumped optical parametric oscillator.

PubMed

Wan, Chenchen; Li, Peng; Ruehl, Axel; Hartl, Ingmar

2018-03-01

Synchronously pumped optical parametric oscillators (OPOs) are important tools for frequency comb (FC) generation in the mid-IR spectral range, where few suitable laser gain materials exist. For degenerate OPOs, self-phase-locking to the pump FC has been demonstrated. Here, we present a phase noise study of the carrier envelope offset frequency, revealing a -6  dB reduction compared to the pump FC over a wide Fourier frequency range. These results demonstrate that a degenerate OPO can be an ideal coherent frequency divider without any excess noise.

Cannabinoid receptors mediate methamphetamine induction of high frequency gamma oscillations in the nucleus accumbens.

PubMed

Morra, Joshua T; Glick, Stanley D; Cheer, Joseph F

2012-09-01

Patients suffering from amphetamine-induced psychosis display repetitive behaviors, partially alleviated by antipsychotics, which are reminiscent of rodent stereotypies. Due to recent evidence implicating endocannabinoid involvement in brain disorders, including psychosis, we studied the effects of endocannabinoid signaling on neuronal oscillations of rats exhibiting methamphetamine stereotypy. Neuronal network oscillations were recorded with multiple single electrode arrays aimed at the nucleus accumbens of freely-moving rats. During the experiments, animals were dosed intravenously with the CB1 receptor antagonist rimonabant (0.3 mg/kg) or vehicle followed by an ascending dose regimen of methamphetamine (0.01, 0.1, 1, and 3 mg/kg; cumulative dosing). The effects of drug administration on stereotypy and local gamma oscillations were evaluated. Methamphetamine treatment significantly increased high frequency gamma oscillations (∼80 Hz). Entrainment of a subpopulation of nucleus accumbens neurons to high frequency gamma was associated with stereotypy encoding in putative fast-spiking interneurons, but not in putative medium spiny neurons. The observed ability of methamphetamine to induce both stereotypy and high frequency gamma power was potently disrupted following CB1 receptor blockade. The present data suggest that CB1 receptor-dependent mechanisms are recruited by methamphetamine to modify striatal interneuron oscillations that accompany changes in psychomotor state, further supporting the link between endocannabinoids and schizophrenia spectrum disorders. Copyright © 2012 Elsevier Ltd. All rights reserved.

Condensate oscillations in a Penrose tiling lattice

NASA Astrophysics Data System (ADS)

Akdeniz, Z.; Vignolo, P.

2017-07-01

We study the dynamics of a Bose-Einstein condensate subject to a particular Penrose tiling lattice. In such a lattice, the potential energy at each site depends on the neighbour sites, accordingly to the model introduced by Sutherland [16]. The Bose-Einstein wavepacket, initially at rest at the lattice symmetry center, is released. We observe a very complex time-evolution that strongly depends on the symmetry center (two choices are possible), on the potential energy landscape dispersion, and on the interaction strength. The condensate-width oscillates at different frequencies and we can identify large-frequency reshaping oscillations and low-frequency rescaling oscillations. We discuss in which conditions these oscillations are spatially bounded, denoting a self-trapping dynamics.

Differential Resonant Ring YIG Tuned Oscillator

NASA Technical Reports Server (NTRS)

Parrott, Ronald A.

2010-01-01

A differential SiGe oscillator circuit uses a resonant ring-oscillator topology in order to electronically tune the oscillator over multi-octave bandwidths. The oscillator s tuning is extremely linear, because the oscillator s frequency depends on the magnetic tuning of a YIG sphere, whose resonant frequency is equal to a fundamental constant times the DC magnetic field. This extremely simple circuit topology uses two coupling loops connecting a differential pair of SiGe bipolar transistors into a feedback configuration using a YIG tuned filter creating a closed-loop ring oscillator. SiGe device technology is used for this oscillator in order to keep the transistor s 1/f noise to an absolute minimum in order to achieve minimum RF phase noise. The single-end resonant ring oscillator currently has an advantage in fewer parts, but when the oscillation frequency is greater than 16 GHz, the package s parasitic behavior couples energy to the sphere and causes holes and poor phase noise performance. This is because the coupling to the YIG is extremely low, so that the oscillator operates at near the unloaded Q. With the differential resonant ring oscillator, the oscillation currents are just in the YIG coupling mechanisms. The phase noise is even better, and the physical size can be reduced to permit monolithic microwave integrated circuit oscillators. This invention is a YIG tuned oscillator circuit making use of a differential topology to simultaneously achieve an extremely broadband electronic tuning range and ultra-low phase noise. As a natural result of its differential circuit topology, all reactive elements, such as tuning stubs, which limit tuning bandwidth by contributing excessive open loop phase shift, have been eliminated. The differential oscillator s open-loop phase shift is associated with completely non-dispersive circuit elements such as the physical angle of the coupling loops, a differential loop crossover, and the high-frequency phase shift of the n

Mammalian synthetic biology: emerging medical applications

PubMed Central

Kis, Zoltán; Pereira, Hugo Sant'Ana; Homma, Takayuki; Pedrigi, Ryan M.; Krams, Rob

2015-01-01

In this review, we discuss new emerging medical applications of the rapidly evolving field of mammalian synthetic biology. We start with simple mammalian synthetic biological components and move towards more complex and therapy-oriented gene circuits. A comprehensive list of ON–OFF switches, categorized into transcriptional, post-transcriptional, translational and post-translational, is presented in the first sections. Subsequently, Boolean logic gates, synthetic mammalian oscillators and toggle switches will be described. Several synthetic gene networks are further reviewed in the medical applications section, including cancer therapy gene circuits, immuno-regulatory networks, among others. The final sections focus on the applicability of synthetic gene networks to drug discovery, drug delivery, receptor-activating gene circuits and mammalian biomanufacturing processes. PMID:25808341

Tremor amplitude and tremor frequency variability in Parkinson's disease is dependent on activity and synchronisation of central oscillators in basal ganglia.

PubMed

Bartolić, Andrej; Pirtosek, Zvezdan; Rozman, Janez; Ribaric, Samo

2010-02-01

Rest tremor is one of the four main clinical features of Parkinson's disease (PD), besides rigidity, bradykinesia and postural instability. While rigidity, bradykinesia and postural instability can be explained with changes in neurotransmitter concentrations and neuronal activity in basal ganglia, the pathogenesis of parkinsonian tremor is not fully understood. According to the leading hypothesis tremor is generated by neurons or groups of neurons in the basal ganglia which act as central oscillators and generate repetitive impulses to the muscles of the body parts involved. The exact morphological substrate for central oscillators and the mechanisms leading to their activation are still an object of debate. Peripheral neural structures exert modulatory influence on tremor amplitude, but not on tremor frequency. We hypothesise that rest tremor in PD is the result of two mechanisms: increased activity and increased synchronisation of central oscillators. We tested our hypothesis by demonstrating that the reduction in rest tremor amplitude is accompanied by increased variability of tremor frequency. The reduction of tremor amplitude is attributed to decreased activity and poor synchronisation of central oscillators in basal ganglia; the increased variability of tremor frequency is attributed to poor synchronisation of the central oscillators. In addition, we demonstrated that the recurrence of clinically visible rest tremor is accompanied by a reduction in tremor frequency variability. This reduction is attributed to increased synchronisation of central oscillators in basal ganglia. We argue that both mechanisms, increased activity of central oscillators and increased synchronisation of central oscillators, are equally important and we predict that tremor becomes clinically evident only when both mechanisms are active at the same time. In circumstances when one of the mechanisms is suppressed tremor amplitude becomes markedly reduced. On the one hand, if the number

The Effect of Doppler Frequency Shift, Frequency Offset of the Local Oscillators, and Phase Noise on the Performance of Coherent OFDM Receivers

NASA Technical Reports Server (NTRS)

Xiong, Fuqin; Andro, Monty

2001-01-01

This paper first shows that the Doppler frequency shift affects the frequencies of the RF carrier, subcarriers, envelope, and symbol timing by the same percentage in an Orthogonal Frequency Division Multiplexing (OFDM) signal or any other modulated signals. Then the SNR degradation of an OFDM system due to Doppler frequency shift, frequency offset of the local oscillators and phase noise is analyzed. Expressions are given and values for 4-, 16-, 64-, and 256-QAM OFDM systems are calculated and plotted. The calculations show that the Doppler shift of the D3 project is about 305 kHz, and the degradation due to it is about 0.01 to 0.04 dB, which is negligible. The degradation due to frequency offset and phase noise of local oscillators will be the main source of degradation. To keep the SNR degradation under 0.1 dB, the relative frequency offset due to local oscillators must be below 0.01 for the 16 QAM-OFDM. This translates to an offset of 1.55 MHz (0.01 x 155 MHz) or a stability of 77.5 ppm (0.01 x 155 MHz/20 GHz) for the DI project. To keep the SNR degradation under 0.1 dB, the relative linewidth (0) due to phase noise of the local oscillators must be below 0.0004 for the 16 QAM-OFDM. This translates to a linewidth of 0.062 MHz (0.0004 x 155 MHz) of the 20 GHz RIF carrier. For a degradation of 1 dB, beta = 0.04, and the linewidth can be relaxed to 6.2 MHz.

Temporal Characteristics of High-Frequency Lower-Limb Oscillation during Freezing of Gait in Parkinson's Disease

PubMed Central

Yungher, Don A.; Morris, Tiffany R.; Dilda, Valentina; Shine, James M.; Naismith, Sharon L.; Lewis, Simon J. G.; Moore, Steven T.

2014-01-01

A cardinal feature of freezing of gait (FOG) is high frequency (3–8 Hz) oscillation of the legs, and this study aimed to quantify the temporal pattern of lower-body motion prior to and during FOG. Acceleration data was obtained from sensors attached to the back, thighs, shanks, and feet in 14 Parkinson's disease patients performing timed-up-and-go tasks, and clinical assessment of FOG was performed by two experienced raters from video. A total of 23 isolated FOG events, defined as occurring at least 5 s after gait initiation and with no preceding FOG, were identified from the clinical ratings. The corresponding accelerometer records were analyzed within a 4 s window centered at the clinical onset of freezing. FOG-related high-frequency oscillation (an increase in power in the 3–8 Hz band >3 SD from baseline) followed a distal to proximal onset pattern, appearing at the feet, shanks, thighs, and then back over a period of 250 ms. Peak power tended to decrease as the focus of oscillation moved from feet to back. There was a consistent delay (mean 872 ms) between the onset of high frequency oscillation at the feet and clinical onset of FOG. We infer that FOG is characterized by high frequency oscillation at the feet, which progresses proximally and is mechanically damped at the torso. PMID:25101189

Amplitude of low-frequency oscillations associated with emotional conflict control.

PubMed

Xue, Song; Wang, Xu; Chang, Jingjing; Liu, Jia; Qiu, Jiang

2016-09-01

Previous fMRI studies related to emotional conflict focused on task activation during the specific experimental paradigm. Yet, the underlying spontaneous neural activity was largely unknown. Here, this was the first study using resting-state fMRI to explore the spontaneous neural activity related to emotional conflict. We used the whole-brain analysis to investigate the association between emotional conflict and amplitude of low-frequency fluctuations (ALFF) in a large sample. We found that the emotional conflict effect was negatively correlated with ALFF in the right AMY. These findings implied that AMY was the key region which plays a crucial role in emotional conflict.

The alteration of spontaneous low frequency oscillations caused by acute electromagnetic fields exposure.

PubMed

Lv, Bin; Chen, Zhiye; Wu, Tongning; Shao, Qing; Yan, Duo; Ma, Lin; Lu, Ke; Xie, Yi

2014-02-01

The motivation of this study is to evaluate the possible alteration of regional resting state brain activity induced by the acute radiofrequency electromagnetic field (RF-EMF) exposure (30min) of Long Term Evolution (LTE) signal. We designed a controllable near-field LTE RF-EMF exposure environment. Eighteen subjects participated in a double-blind, crossover, randomized and counterbalanced experiment including two sessions (real and sham exposure). The radiation source was close to the right ear. Then the resting state fMRI signals of human brain were collected before and after the exposure in both sessions. We measured the amplitude of low frequency fluctuation (ALFF) and fractional ALFF (fALFF) to characterize the spontaneous brain activity. We found the decreased ALFF value around in left superior temporal gyrus, left middle temporal gyrus, right superior temporal gyrus, right medial frontal gyrus and right paracentral lobule after the real exposure. And the decreased fALFF value was also detected in right medial frontal gyrus and right paracentral lobule. The study provided the evidences that 30min LTE RF-EMF exposure modulated the spontaneous low frequency fluctuations in some brain regions. With resting state fMRI, we found the alteration of spontaneous low frequency fluctuations induced by the acute LTE RF-EMF exposure. Copyright © 2013 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

Computational Re-design of Synthetic Genetic Oscillators for Independent Amplitude and Frequency Modulation.

PubMed

Tomazou, Marios; Barahona, Mauricio; Polizzi, Karen M; Stan, Guy-Bart

2018-04-25

To perform well in biotechnology applications, synthetic genetic oscillators must be engineered to allow independent modulation of amplitude and period. This need is currently unmet. Here, we demonstrate computationally how two classic genetic oscillators, the dual-feedback oscillator and the repressilator, can be re-designed to provide independent control of amplitude and period and improve tunability-that is, a broad dynamic range of periods and amplitudes accessible through the input "dials." Our approach decouples frequency and amplitude modulation by incorporating an orthogonal "sink module" where the key molecular species are channeled for enzymatic degradation. This sink module maintains fast oscillation cycles while alleviating the translational coupling between the oscillator's transcription factors and output. We characterize the behavior of our re-designed oscillators over a broad range of physiologically reasonable parameters, explain why this facilitates broader function and control, and provide general design principles for building synthetic genetic oscillators that are more precisely controllable. Copyright © 2018 The Authors. Published by Elsevier Inc. All rights reserved.

Hybrid nanogenerators for low frequency vibration energy harvesting and self-powered wireless locating

NASA Astrophysics Data System (ADS)

Yuan, Ying; Zhang, Hulin; Wang, Jie; Xie, Yuhang; Khan, Saeed Ahmed; Jin, Long; Yan, Zhuocheng; Huang, Long; Pan, Taisong; Yang, Weiqing; Lin, Yuan

2018-01-01

Hybrid energy harvesters based on different physical effects is fascinating, but a rational design for multiple energy harvesting is challenging. In this work, a spring-magnet oscillator-based triboelectric-electromagnetic generator (EMG) with a solar cell cap is proposed. A power was produced by a triboelectric nanogenerator (TENG) and an EMG independently or simultaneously by using a shared spring-magnet oscillator. The oscillator configuration enables versatile energy harvesting with the excellent size scalability and self-packaged structure which can perform well at low frequency ranging from 3.5 to 5 Hz. The solar cell cap mounted above the oscillator can harvest solar energy. Under vibrations at the frequency of 4 Hz, the TENG and the EMG produced maximum output power of 5.46 nW cm-3 and 378.79 μW cm-3, respectively. The generated electricity by the hybrid nanogenerator can be stored in a capacitor or Li-ion battery, which is capable of powering a wireless locator for real-time locating data reporting to a personal cell phone. The light-weight and handy hybrid nanogenerator can directly light a caution light or play as a portable flashlight by shaking hands at night.

Cortical drive of low-frequency oscillations in the human nucleus accumbens during action selection

PubMed Central

Litvak, Vladimir; Rutledge, Robb B.; Zaehle, Tino; Schmitt, Friedhelm C.; Voges, Jürgen; Heinze, Hans-Jochen; Dolan, Raymond J.

2015-01-01

The nucleus accumbens is thought to contribute to action selection by integrating behaviorally relevant information from multiple regions, including prefrontal cortex. Studies in rodents suggest that information flow to the nucleus accumbens may be regulated via task-dependent oscillatory coupling between regions. During instrumental behavior, local field potentials (LFP) in the rat nucleus accumbens and prefrontal cortex are coupled at delta frequencies (Gruber AJ, Hussain RJ, O'Donnell P. PLoS One 4: e5062, 2009), possibly mediating suppression of afferent input from other areas and thereby supporting cortical control (Calhoon GG, O'Donnell P. Neuron 78: 181–190, 2013). In this report, we demonstrate low-frequency cortico-accumbens coupling in humans, both at rest and during a decision-making task. We recorded LFP from the nucleus accumbens in six epilepsy patients who underwent implantation of deep brain stimulation electrodes. All patients showed significant coherence and phase-synchronization between LFP and surface EEG at delta and low theta frequencies. Although the direction of this coupling as indexed by Granger causality varied between subjects in the resting-state data, all patients showed a cortical drive of the nucleus accumbens during action selection in a decision-making task. In three patients this was accompanied by a significant coherence increase over baseline. Our results suggest that low-frequency cortico-accumbens coupling represents a highly conserved regulatory mechanism for action selection. PMID:25878159

In vitro Neurons in Mammalian Cortical Layer 4 Exhibit Intrinsic Oscillatory Activity in the 10- to 50-Hz Frequency Range

NASA Astrophysics Data System (ADS)

Llinas, Rodolfo R.; Grace, Anthony A.; Yarom, Yosef

1991-02-01

We report here the presence of fast subthreshold oscillatory potentials recorded in vitro from neurons within layer 4 of the guinea pig frontal cortex. Two types of oscillatory neurons were recorded: (i) One type exhibited subthreshold oscillations whose frequency increased with membrane depolarization and encompassed a range of 10-45 Hz. Action potentials in this type of neuron demonstrated clear after-hyperpolarizations. (ii) The second type of neuron was characterized by narrow-frequency oscillations near 35-50 Hz. These oscillations often outlasted the initiating depolarizing stimulus. No calcium component could be identified in their action potential. In both types of cell the subthreshold oscillations were tetrodotoxin-sensitive, indicating that the depolarizing phase of the oscillation was generated by a voltage-dependent sodium conductance. The initial depolarizing phase was followed by a potassium conductance responsible for the falling phase of the oscillatory wave. In both types of cell, the subthreshold oscillation could trigger spikes at the oscillatory frequency, if the membrane was sufficiently depolarized. Combining intracellular recordings with Lucifer yellow staining showed that the narrow-frequency oscillatory activity was produced by a sparsely spinous interneuron located in layer 4 of the cortex. This neuron has extensive local axonal collaterals that ramify in layers 3 and 4 such that they may contribute to the columnar synchronization of activity in the 40- to 50-Hz range. Cortical activity in this frequency range has been proposed as the basis for the "conjunctive properties" of central nervous system networks.

Frequency pulling in a low-voltage medium-power gyrotron

NASA Astrophysics Data System (ADS)

Luo, Li; Du, Chao-Hai; Huang, Ming-Guang; Liu, Pu-Kun

2018-04-01

Many recent biomedical applications use medium-power frequency-tunable terahertz (THz) sources, such as sensitivity-enhanced nuclear magnetic resonance, THz imaging, and biomedical treatment. As a promising candidate, a low-voltage gyrotron can generate watt-level, continuous THz-wave radiation. In particular, the frequency-pulling effect in a gyrotron, namely, the effect of the electron beam parameters on the oscillation frequency, can be used to tune the operating frequency. Most previous investigations used complicated and time-consuming gyrotron nonlinear theory to study the influence of many beam parameters on the interaction performance. While gyrotron linear theory investigation demonstrates the advantages of rapidly and clearly revealing the physical influence of individual key beam parameters on the overall system performance, this paper demonstrates systematically the use of gyrotron linear theory to study the frequency-pulling effect in a low-voltage gyrotron with either a Gaussian or a sinusoidal axial-field profile. Furthermore, simulations of a gyrotron operating in the first axial mode are carried out in the framework of nonlinear theory as a contrast. Close agreement is achieved between the two theories. Besides, some interesting results are obtained. In a low-current sinusoidal-profile cavity, the ranges of frequency variation for different axial modes are isolated from each other, and the frequency tuning bandwidth for each axial mode increases by increasing either the beam voltage or pitch factor. Lowering the voltage, the total tuning ranges are squeezed and become concentrated. However, the isolated frequency regions of each axial mode cannot be linked up unless the beam current is increased, meaning that higher current operation is the key to achieving a wider and continuous tuning frequency range. The results presented in this paper can provide a reference for designing a broadband low-voltage gyrotron.

Crystal oscillators using negative voltage gain, single pole response amplifiers

NASA Technical Reports Server (NTRS)

Kleinberg, Leonard L. (Inventor)

1989-01-01

A simple and inexpensive crystal oscillator is provided which employs negative voltage gain, single pole response amplifiers. The amplifiers may include such configurations as gate inverters, operational amplifiers and conventional bipolar transistor amplifiers, all of which operate at a frequency which is on the roll-off portion of their gain versus frequency curve. Several amplifier feedback circuit variations are employed to set desired bias levels and to allow the oscillator to operate at the crystal's fundamental frequency or at an overtone of the fundamental frequency. The oscillator is made less expensive than comparable oscillators by employing relatively low frequency amplifiers and operating them at roll-off, at frequencies beyond which they are customarily used. Simplicity is provided because operation at roll-off eliminates components ordinarily required in similar circuits to provide sufficient phase-shift in the feedback circuitry for oscillation to occur.

Multiscale low-frequency circulation modes in the global atmosphere

NASA Technical Reports Server (NTRS)

Lau, K.-M.; Sheu, P.-J.; Kang, I.-S.

1994-01-01

In this paper, fundamental multiscale circulation modes in the global atmosphere are identified with the objective of providing better understanding of atmospheric low-frequency variabilities over a wide range of spatial and temporal scales. With the use of a combination of rotated principal component technique, singular spectrum analysis, and phase space portraits, three categories of basic multiscale modes in the atmosphere are found. The first is the interannual-mode (IAM), which is dominated by time scales longer than a year and can be attributed to heating and circulation anomalies associated with the coupled tropical ocean-atmosphere, in particular the El Nino-Southern Oscillation. The second is a set of tropical intraseasonal modes consisting of three separate multiscale patterns (ISO-1, -2, -3) related to tropical heating that can be identified with the different phases of the Madden-Julian Oscillation (MJO), including its teleconnection to the extratropics. The ISO spatial and temporal patterns suggest that the extratropical wave train in the North Pacific and North America is related to heating over the Maritime Continent and that the evolution of the MJO around the equator may require forcing from the extratropics spawning convection over the Indian Ocean. The third category represents extratropical intraseasonal oscillations arising from internal dynamics of the basic-state circulation. In the Northern Hemisphere, there are two distinct circulation modes with multiple frequencies in this category: the Pacific/North America (PNA) and the North Atlantic/Eurasia (NAE). In the Southern Hemisphere, two phase-locked modes (PSA-1 and PSA-2) are found depicting an eastward propagating wave train from eastern Australia, via the Pacific South America to the South Atlantic. The extratropical modes exhibit temporal characteristics such as phase locking and harmonic oscillations possibly associated with quadratically nonlinear dynamical systems. Additionally, the

Isoflurane Impairs Low-Frequency Feedback but Leaves High-Frequency Feedforward Connectivity Intact in the Fly Brain.

PubMed

Cohen, Dror; van Swinderen, Bruno; Tsuchiya, Naotsugu

2018-01-01

Hierarchically organized brains communicate through feedforward (FF) and feedback (FB) pathways. In mammals, FF and FB are mediated by higher and lower frequencies during wakefulness. FB is preferentially impaired by general anesthetics in multiple mammalian species. This suggests FB serves critical functions in waking brains. The brain of Drosophila melanogaster (fruit fly) is also hierarchically organized, but the presence of FB in these brains is not established. Here, we studied FB in the fly brain, by simultaneously recording local field potentials (LFPs) from low-order peripheral structures and higher-order central structures. We analyzed the data using Granger causality (GC), the first application of this analysis technique to recordings from the insect brain. Our analysis revealed that low frequencies (0.1-5 Hz) mediated FB from the center to the periphery, while higher frequencies (10-45 Hz) mediated FF in the opposite direction. Further, isoflurane anesthesia preferentially reduced FB. Our results imply that the spectral characteristics of FF and FB may be a signature of hierarchically organized brains that is conserved from insects to mammals. We speculate that general anesthetics may induce unresponsiveness across species by targeting the mechanisms that support FB.

Isoflurane Impairs Low-Frequency Feedback but Leaves High-Frequency Feedforward Connectivity Intact in the Fly Brain

PubMed Central

2018-01-01

Abstract Hierarchically organized brains communicate through feedforward (FF) and feedback (FB) pathways. In mammals, FF and FB are mediated by higher and lower frequencies during wakefulness. FB is preferentially impaired by general anesthetics in multiple mammalian species. This suggests FB serves critical functions in waking brains. The brain of Drosophila melanogaster (fruit fly) is also hierarchically organized, but the presence of FB in these brains is not established. Here, we studied FB in the fly brain, by simultaneously recording local field potentials (LFPs) from low-order peripheral structures and higher-order central structures. We analyzed the data using Granger causality (GC), the first application of this analysis technique to recordings from the insect brain. Our analysis revealed that low frequencies (0.1–5 Hz) mediated FB from the center to the periphery, while higher frequencies (10–45 Hz) mediated FF in the opposite direction. Further, isoflurane anesthesia preferentially reduced FB. Our results imply that the spectral characteristics of FF and FB may be a signature of hierarchically organized brains that is conserved from insects to mammals. We speculate that general anesthetics may induce unresponsiveness across species by targeting the mechanisms that support FB. PMID:29541686

Low-frequency sound affects active micromechanics in the human inner ear

PubMed Central

Kugler, Kathrin; Wiegrebe, Lutz; Grothe, Benedikt; Kössl, Manfred; Gürkov, Robert; Krause, Eike; Drexl, Markus

2014-01-01

Noise-induced hearing loss is one of the most common auditory pathologies, resulting from overstimulation of the human cochlea, an exquisitely sensitive micromechanical device. At very low frequencies (less than 250 Hz), however, the sensitivity of human hearing, and therefore the perceived loudness is poor. The perceived loudness is mediated by the inner hair cells of the cochlea which are driven very inadequately at low frequencies. To assess the impact of low-frequency (LF) sound, we exploited a by-product of the active amplification of sound outer hair cells (OHCs) perform, so-called spontaneous otoacoustic emissions. These are faint sounds produced by the inner ear that can be used to detect changes of cochlear physiology. We show that a short exposure to perceptually unobtrusive, LF sounds significantly affects OHCs: a 90 s, 80 dB(A) LF sound induced slow, concordant and positively correlated frequency and level oscillations of spontaneous otoacoustic emissions that lasted for about 2 min after LF sound offset. LF sounds, contrary to their unobtrusive perception, strongly stimulate the human cochlea and affect amplification processes in the most sensitive and important frequency range of human hearing. PMID:26064536

Cortical drive of low-frequency oscillations in the human nucleus accumbens during action selection.

PubMed

Stenner, Max-Philipp; Litvak, Vladimir; Rutledge, Robb B; Zaehle, Tino; Schmitt, Friedhelm C; Voges, Jürgen; Heinze, Hans-Jochen; Dolan, Raymond J

2015-07-01

The nucleus accumbens is thought to contribute to action selection by integrating behaviorally relevant information from multiple regions, including prefrontal cortex. Studies in rodents suggest that information flow to the nucleus accumbens may be regulated via task-dependent oscillatory coupling between regions. During instrumental behavior, local field potentials (LFP) in the rat nucleus accumbens and prefrontal cortex are coupled at delta frequencies (Gruber AJ, Hussain RJ, O'Donnell P. PLoS One 4: e5062, 2009), possibly mediating suppression of afferent input from other areas and thereby supporting cortical control (Calhoon GG, O'Donnell P. Neuron 78: 181-190, 2013). In this report, we demonstrate low-frequency cortico-accumbens coupling in humans, both at rest and during a decision-making task. We recorded LFP from the nucleus accumbens in six epilepsy patients who underwent implantation of deep brain stimulation electrodes. All patients showed significant coherence and phase-synchronization between LFP and surface EEG at delta and low theta frequencies. Although the direction of this coupling as indexed by Granger causality varied between subjects in the resting-state data, all patients showed a cortical drive of the nucleus accumbens during action selection in a decision-making task. In three patients this was accompanied by a significant coherence increase over baseline. Our results suggest that low-frequency cortico-accumbens coupling represents a highly conserved regulatory mechanism for action selection. Copyright © 2015 the American Physiological Society.

A wide-range variable-frequency resonant tunneling diode oscillator using a variable resonator suitable for simple MEMS process

NASA Astrophysics Data System (ADS)

Yamashita, Takashi; Nakano, Daisuke; Mori, Masayuki; Maezawa, Koichi

2018-04-01

A resonant tunneling diode oscillator having a wide frequency variation range based on a novel MEMS resonator was proposed, which exploits the change in the signal propagation velocity on a coplanar waveguide according to a movable ground plane. First, we discussed the velocity modulation mechanism, and clarified the importance of the dielectric constant of the substrate. Then, a prototype device oscillating in a 10 to 20 GHz frequency range was fabricated to demonstrate the basic operation. A large and continuous increase in the oscillation frequency of about two times was achieved with this device. This is promising for various applications including THz spectroscopy.

Electronically tunable phase locked loop oscillator

NASA Astrophysics Data System (ADS)

Balasis, M.; Davis, M. R.; Jackson, C. R.

1982-02-01

This report describes the design and development of a low noise, high power, variable oscillator incorporating a high 'Q' electronically tunable resonator as the frequency determining element. The VCO provides improved EMC performance in phase locked synthesizers which are a part of communications equipments. The oscillator combines a low noise VMOS transistor with the selectivity and out-of-band attenuation of a coaxial resonator to provide superior EMC performance. Several oscillator designs were examined and the basis for the final configuration is presented. Oscillator noise is discussed and models for analysis are explained. A brass board model was constructed and tested and the technical results are presented.

Frequency stability and offset locking of a laser-diode-pumped Nd:YAG monolithic nonplanar ring oscillator

NASA Technical Reports Server (NTRS)

Kane, Thomas J.; Nilsson, Alan C.; Byer, Robert L.

1987-01-01

The frequency stability of laser-diode-pumped, monolithic Nd:YAG solid-state unidirectional nonplanar ring oscillators was studied by heterodyne measurements. CW single-axial- and transverse-mode power of 25 mW at 1064 nm was obtained at a slope efficiency of 19 percent. Two independent oscillators were offset-locked at 17 MHz with frequency fluctuations of less than + or - 40 kHz for periods of 8 min.

Calculations of wall shear stress in harmonically oscillated turbulent pipe flow using a low-Reynolds-number {kappa}-{epsilon} model

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ismael, J.O.; Cotton, M.A.

1996-03-01

The low-Reynolds-number {kappa}-{epsilon} turbulence model of Launder and Sharma is applied to the calculation of wall shear stress in spatially fully-developed turbulent pipe flow oscillated at small amplitudes. It is believed that the present study represents the first systematic evaluation of the turbulence closure under consideration over a wide range of frequency. Model results are well correlated in terms of the parameter {omega}{sup +} = {omega}{nu}/{bar U}{sub {tau}}{sup 2} at high frequencies, whereas at low frequencies there is an additional Reynolds number dependence. Comparison is made with the experimental data of Finnicum and Hanratty.

A Constant Energy-Per-Cycle Ring Oscillator Over a Wide Frequency Range for Wireless Sensor Nodes

PubMed Central

Lee, Inhee; Sylvester, Dennis; Blaauw, David

2016-01-01

This paper presents an energy-efficient oscillator for wireless sensor nodes (WSNs). It avoids short-circuit current by minimizing the time spent in the input voltage range from Vthn to [Vdd − |Vthp|]. A current-feeding scheme with gate voltage control enables the oscillator to operate over a wide frequency range. A test chip is fabricated in a 0.18 μm CMOS process. The measurements show that the proposed oscillator achieves a constant energy-per-cycle (EpC) of 0.8 pJ/cycle over the 21–60 MHz frequency range and is more efficient than a conventional current-starved ring oscillator (CSRO) below 300 kHz at 1.8 V supply voltage. As an application example, the proposed oscillator is implemented in a switched-capacitor DC–DC converter. The converter is 11%–56% more efficient for load power values ranging from 583 pW to 2.9 nW than a converter using a conventional CSRO. PMID:27546899

A Constant Energy-Per-Cycle Ring Oscillator Over a Wide Frequency Range for Wireless Sensor Nodes.

PubMed

Lee, Inhee; Sylvester, Dennis; Blaauw, David

2016-03-01

This paper presents an energy-efficient oscillator for wireless sensor nodes (WSNs). It avoids short-circuit current by minimizing the time spent in the input voltage range from V thn to [ V dd - | V thp |]. A current-feeding scheme with gate voltage control enables the oscillator to operate over a wide frequency range. A test chip is fabricated in a 0.18 μm CMOS process. The measurements show that the proposed oscillator achieves a constant energy-per-cycle (EpC) of 0.8 pJ/cycle over the 21-60 MHz frequency range and is more efficient than a conventional current-starved ring oscillator (CSRO) below 300 kHz at 1.8 V supply voltage. As an application example, the proposed oscillator is implemented in a switched-capacitor DC-DC converter. The converter is 11%-56% more efficient for load power values ranging from 583 pW to 2.9 nW than a converter using a conventional CSRO.

Mammalian synthetic biology: emerging medical applications.

PubMed

Kis, Zoltán; Pereira, Hugo Sant'Ana; Homma, Takayuki; Pedrigi, Ryan M; Krams, Rob

2015-05-06

In this review, we discuss new emerging medical applications of the rapidly evolving field of mammalian synthetic biology. We start with simple mammalian synthetic biological components and move towards more complex and therapy-oriented gene circuits. A comprehensive list of ON-OFF switches, categorized into transcriptional, post-transcriptional, translational and post-translational, is presented in the first sections. Subsequently, Boolean logic gates, synthetic mammalian oscillators and toggle switches will be described. Several synthetic gene networks are further reviewed in the medical applications section, including cancer therapy gene circuits, immuno-regulatory networks, among others. The final sections focus on the applicability of synthetic gene networks to drug discovery, drug delivery, receptor-activating gene circuits and mammalian biomanufacturing processes. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

Downstream boundary effects on the frequency of self-excited oscillations in transonic diffuser flows

NASA Astrophysics Data System (ADS)

Hsieh, T.

1986-10-01

Investigation of downstream boundary effects on the frequency of self-excited oscillations in two-dimensional, separated transonic diffuser flows were conducted numerically by solving the compressible, Reynolds-averaged, thin-layer Navier-Stokes equation with two equation turbulence models. It was found that the flow fields are very sensitive to the location of the downstream boundary. Extension of the diffuser downstream boundary significantly reduces the frequency and amplitude of oscillations for pressure, velocity, and shock. The existence of a suction slot in the experimental setpup obscures the physical downstream boundary and therefore presents a difficulty for quantitative comparisons between computation and experiment.

Brain state-dependent recruitment of high-frequency oscillations in the human hippocampus.

PubMed

Billeke, Pablo; Ossandon, Tomas; Stockle, Marcelo; Perrone-Bertolotti, Marcela; Kahane, Philippe; Lachaux, Jean-Philippe; Fuentealba, Pablo

2017-09-01

Ripples are high-frequency bouts of coordinated hippocampal activity believed to be crucial for information transfer and memory formation. We used intracortical macroelectrodes to record neural activity in the human hippocampus of awake subjects undergoing surgical treatment for refractory epilepsy and distinguished two populations of ripple episodes based on their frequency spectrum. The phase-coupling of one population, slow ripples (90-110 Hz), to cortical delta oscillations was differentially modulated by cognitive task; whereas the second population, fast ripples (130-170 Hz), was not seemingly correlated to local neural activity. Furthermore, as cognitive tasks changed, the ongoing coordination of neural activity associated to slow ripples progressively augmented along the parahippocampal axis. Thus, during resting states, slow ripples were coordinated in restricted hippocampal territories; whereas during active states, such as attentionally-demanding tasks, high frequency activity emerged across the hippocampus and parahippocampal cortex, that was synchronized with slow ripples, consistent with ripples supporting information transfer and coupling anatomically distant regions. Hence, our results provide further evidence of neural diversity in hippocampal high-frequency oscillations and their association to cognitive processing in humans. Copyright © 2017 Elsevier Ltd. All rights reserved.

Observation of millimeter-wave oscillations from resonant tunneling diodes and some theoretical considerations of ultimate frequency limits

NASA Technical Reports Server (NTRS)

Sollner, T. C. L. G.; Brown, E. R.; Goodhue, W. D.; Le, H. Q.

1987-01-01

Recent observations of oscillation frequencies up to 56 GHz in resonant tunneling structures are discussed in relation to calculations by several authors of the ultimate frequency limits of these devices. It is found that calculations relying on the Wentzel-Kramers-Brillouin (WKB) approximation give limits well below the observed oscillation frequencies. Two other techniques for calculating the upper frequency limit were found to give more reasonable results. One method employs the solution of the time-dependent Schroedinger equation obtained by Kundrotas and Dargys (1986); the other uses the energy width of the transmission function for electrons through the double-barrier structure. This last technique is believed to be the most accurate since it is based on general results for the lifetime of any resonant state. It gives frequency limits on the order of 1 THz for two recently fabricated structures. It appears that the primary limitation of the oscillation frequency for double-barrier resonant-tunneling diodes is imposed by intrinsic device circuit parameters and by the transit time of the depletion layer rather than by time delays encountered in the double-barrier region.

Light-dark cycle memory in the mammalian suprachiasmatic nucleus.

PubMed

Ospeck, Mark C; Coffey, Ben; Freeman, Dave

2009-09-16

The mammalian circadian oscillator, or suprachiasmatic nucleus (SCN), contains several thousand clock neurons in its ventrolateral division, many of which are spontaneous oscillators with period lengths that range from 22 to 28 h. In complete darkness, this network synchronizes through the exchange of action potentials that release vasoactive intestinal polypeptide, striking a compromise, free-running period close to 24 h long. We entrained Siberian hamsters to various light-dark cycles and then tracked their activity into constant darkness to show that they retain a memory of the previous light-dark cycle before returning to their own free-running period. Employing Leloup-Goldbeter mammalian clock neurons we model the ventrolateral SCN network and show that light acting weakly upon a strongly rhythmic vasoactive intestinal polypeptide oscillation can explain the observed light-dark cycle memory. In addition, light is known to initiate a mitogen-activated protein kinase signaling cascade that induces transcription of both per and mkp1 phosphatase. We show that the ensuing phosphatase-kinase interaction can account for the dead zone in the mammalian phase response curve and hypothesize that the SCN behaves like a lock-in amplifier to entrain to the light edges of the circadian day.

The Trade-Off Mechanism in Mammalian Circadian Clock Model with Two Time Delays

NASA Astrophysics Data System (ADS)

Yan, Jie; Kang, Xiaxia; Yang, Ling

Circadian clock is an autonomous oscillator which orchestrates the daily rhythms of physiology and behaviors. This study is devoted to explore how a positive feedback loop affects the dynamics of mammalian circadian clock. We simplify an experimentally validated mathematical model in our previous work, to a nonlinear differential equation with two time delays. This simplified mathematical model incorporates the pacemaker of mammalian circadian clock, a negative primary feedback loop, and a critical positive auxiliary feedback loop, Rev-erbα/Cry1 loop. We perform analytical studies of the system. Delay-dependent conditions for the asymptotic stability of the nontrivial positive steady state of the model are investigated. We also prove the existence of Hopf bifurcation, which leads to self-sustained oscillation of mammalian circadian clock. Our theoretical analyses show that the oscillatory regime is reduced upon the participation of the delayed positive auxiliary loop. However, further simulations reveal that the auxiliary loop can enable the circadian clock gain widely adjustable amplitudes and robust period. Thus, the positive auxiliary feedback loop may provide a trade-off mechanism, to use the small loss in the robustness of oscillation in exchange for adaptable flexibility in mammalian circadian clock. The results obtained from the model may gain new insights into the dynamics of biological oscillators with interlocked feedback loops.

Rabi-Bloch oscillations in spatially distributed systems: Temporal dynamics and frequency spectra

NASA Astrophysics Data System (ADS)

Levie, Ilay; Kastner, Raphael; Slepyan, Gregory

2017-10-01

We consider one-dimensional chains of two-level quantum systems coupled via tunneling. The chain is driven by the superposition of dc and ac fields in the strong coupling regime. Based on the fundamental principles of electrodynamics and quantum theory, we have developed a generalized model of quantum dynamics for such interactions, free of rotating-wave approximation. The system of equations of motion was studied numerically. We analyzed the dynamics and spectra of the inversion density, dipole current density, and tunneling current density. In the case of resonant interaction with the ac component, the particle dynamics exhibits itself in the oscillatory regime, which may be interpreted as a combination of Rabi and Bloch oscillations with their strong mutual influence. Such scenario for an obliquely incident ac field dramatically differs from the individual picture of both types of oscillations due to the interactions. This effect is counterintuitive because of the existence of markedly different frequency ranges for such two types of oscillations. These dynamics manifest themselves in multiline spectra in different combinations of Rabi and Bloch frequencies. The effect is promising as a framework of a new type of spectroscopy in nanoelectronics and electrical control of nanodevices.

A probabilistic analysis of the crystal oscillator behavior at low drive levels

NASA Astrophysics Data System (ADS)

Shmaliy, Yuriy S.; Brendel, Rémi

2008-03-01

The paper discusses a probabilistic model of a crystal oscillator at low drive levels where the noise intensity is comparable with the oscillation amplitude. The stationary probability density of the oscillations envelope is derived and investigated for the nonlinear resonator loses. A stochastic explanation is given for the well-known phenomenon termed sleeping sickness associated with losing a facility of self-excitation by a crystal oscillator after a long storage without a power supply. It is shown that, with low drive levels leading to an insufficient feedback, a crystal oscillator generates the noise-induced oscillations rather than it absolutely "falls in sleep".

High frequency optoelectronic oscillators based on the optical feedback of semiconductor mode-locked laser diodes.

PubMed

Haji, Mohsin; Hou, Lianping; Kelly, Anthony E; Akbar, Jehan; Marsh, John H; Arnold, John M; Ironside, Charles N

2012-01-30

Optical self seeding feedback techniques can be used to improve the noise characteristics of passively mode-locked laser diodes. External cavities such as fiber optic cables can increase the memory of the phase and subsequently improve the timing jitter. In this work, an improved optical feedback architecture is proposed using an optical fiber loop delay as a cavity extension of the mode-locked laser. We investigate the effect of the noise reduction as a function of the loop length and feedback power. The well known composite cavity technique is also implemented for suppressing supermode noise artifacts presented due to harmonic mode locking effects. Using this method, we achieve a record low radio frequency linewidth of 192 Hz for any high frequency (>1 GHz) passively mode-locked laser to date (to the best of the authors' knowledge), making it promising for the development of high frequency optoelectronic oscillators.

Detection of the adsorption of water monolayers through the ion oscillation frequency in the magnesium oxide lattice by means of low energy electron diffraction

DOE Office of Scientific and Technical Information (OSTI.GOV)

Guevara-Bertsch, M.; Avendaño, E.; Centro de Investigación en Ciencia e Ingeniería de Materiales, Universidad de Costa Rica, 2060 San Pedro, San José

We investigate the variation of the oscillation frequency of the Mg{sup 2+} and O{sup 2−} ions in the magnesium oxide lattice due to the interactions of the surface with water monolayers by means of Low Energy Electron Diffraction. Our key result is a new technique to determine the adsorbate vibrations produced by the water monolayers on the surface lattice as a consequence of their change in the surface Debye temperature and its chemical shift. The latter was systematically investigated for different annealing times and for a constant external thermal perturbation in the range of 110–300 K in order to accomplish adsorptionmore » or desorption of water monolayers in the surface lattice.« less

Demonstration of a Submillimeter-Wave HEMT Oscillator Module at 330 GHz

NASA Technical Reports Server (NTRS)

Radisic, Vesna; Deal, W. R.; Mei, X. B.; Yoshida, Wayne; Liu, P. H.; Uyeda, Jansen; Lai, Richard; Samoska, Lorene; Fung, King Man; Gaier, Todd;

Respiratory Control in Stuttering Speakers: Evidence from Respiratory High-Frequency Oscillations.

ERIC Educational Resources Information Center

Denny, Margaret; Smith, Anne

2000-01-01

This study examined whether stuttering speakers (N=10) differed from fluent speakers in relations between the neural control systems for speech and life support. It concluded that in some stuttering speakers the relations between respiratory controllers are atypical, but that high participation by the high frequency oscillation-producing circuitry…

Probing a chemical compass: novel variants of low-frequency reaction yield detected magnetic resonance.

PubMed

Maeda, Kiminori; Storey, Jonathan G; Liddell, Paul A; Gust, Devens; Hore, P J; Wedge, C J; Timmel, Christiane R

2015-02-07

We present a study of a carotenoid-porphyrin-fullerene triad previously shown to function as a chemical compass: the photogenerated carotenoid-fullerene radical pair recombines at a rate sensitive to the orientation of an applied magnetic field. To characterize the system we develop a time-resolved Low-Frequency Reaction Yield Detected Magnetic Resonance (tr-LF-RYDMR) technique; the effect of varying the relative orientation of applied static and 36 MHz oscillating magnetic fields is shown to be strongly dependent on the strength of the oscillating magnetic field. RYDMR is a diagnostic test for involvement of the radical pair mechanism in the magnetic field sensitivity of reaction rates or yields, and has previously been applied in animal behavioural experiments to verify the involvement of radical-pair-based intermediates in the magnetic compass sense of migratory birds. The spectroscopic selection rules governing RYDMR are well understood at microwave frequencies for which the so-called 'high-field approximation' is valid, but at lower frequencies different models are required. For example, the breakdown of the rotating frame approximation has recently been investigated, but less attention has so far been given to orientation effects. Here we gain physical insights into the interplay of the different magnetic interactions affecting low-frequency RYDMR experiments performed in the challenging regime in which static and oscillating applied magnetic fields as well as internal electron-nuclear hyperfine interactions are of comparable magnitude. Our observations aid the interpretation of existing RYDMR-based animal behavioural studies and will inform future applications of the technique to verify and characterize further the biological receptors involved in avian magnetoreception.

Wideband, low-frequency springless vibration energy harvesters: part I

NASA Astrophysics Data System (ADS)

Bendame, Mohamed; Abdel-Rahman, Eihab; Soliman, Mostafa

2016-11-01

We present a novel architecture for wideband and low-frequency vibration energy harvesting (VEH). Springless vibration energy harvesters (SVEH) employ impact oscillators as energy harvesting elements. A seismic mass moves along a linear guide limited by stoppers at both ends of the track. An electromagnetic transducer converts the kinetic energy captured by the mass into electrical energy. Experiments using prototypes of the horizontal SVEH demonstrated low frequency harvesting (<20 Hz), wideband harvesting (up to 6.0 Hz), and an optimal rectified output power of P  =  12 mW for a base acceleration amplitude of 0.5 g. A model of the electromagnetic SVEH was developed and validated experimentally. A figure of merit was defined to quantify realizable output power in linear and nonlinear VEHs. Comparison using this figure of merit shows that electromagnetic SVEHs outperform their linear counterparts by 92%-232% for acceleration amplitudes in the range of 0.4-0.6 g.

THEORETICAL p-MODE OSCILLATION FREQUENCIES FOR THE RAPIDLY ROTATING {delta} SCUTI STAR {alpha} OPHIUCHI

DOE Office of Scientific and Technical Information (OSTI.GOV)

Deupree, Robert G., E-mail: bdeupree@ap.smu.ca

2011-11-20

A rotating, two-dimensional stellar model is evolved to match the approximate conditions of {alpha} Oph. Both axisymmetric and nonaxisymmetric oscillation frequencies are computed for two-dimensional rotating models which approximate the properties of {alpha} Oph. These computed frequencies are compared to the observed frequencies. Oscillation calculations are made assuming the eigenfunction can be fitted with six Legendre polynomials, but comparison calculations with eight Legendre polynomials show the frequencies agree to within about 0.26% on average. The surface horizontal shape of the eigenfunctions for the two sets of assumed number of Legendre polynomials agrees less well, but all calculations show significant departuresmore » from that of a single Legendre polynomial. It is still possible to determine the large separation, although the small separation is more complicated to estimate. With the addition of the nonaxisymmetric modes with |m| {<=} 4, the frequency space becomes sufficiently dense that it is difficult to comment on the adequacy of the fit of the computed to the observed frequencies. While the nonaxisymmetric frequency mode splitting is no longer uniform, the frequency difference between the frequencies for positive and negative values of the same m remains 2m times the rotation rate.« less

Fast, precise, and widely tunable frequency control of an optical parametric oscillator referenced to a frequency comb.

PubMed

Prehn, Alexander; Glöckner, Rosa; Rempe, Gerhard; Zeppenfeld, Martin

2017-03-01

Optical frequency combs (OFCs) provide a convenient reference for the frequency stabilization of continuous-wave lasers. We demonstrate a frequency control method relying on tracking over a wide range and stabilizing the beat note between the laser and the OFC. The approach combines fast frequency ramps on a millisecond timescale in the entire mode-hop free tuning range of the laser and precise stabilization to single frequencies. We apply it to a commercially available optical parametric oscillator (OPO) and demonstrate tuning over more than 60 GHz with a ramping speed up to 3 GHz/ms. Frequency ramps spanning 15 GHz are performed in less than 10 ms, with the OPO instantly relocked to the OFC after the ramp at any desired frequency. The developed control hardware and software are able to stabilize the OPO to sub-MHz precision and to perform sequences of fast frequency ramps automatically.

Self-entrainment to optimal gaits of an underactuated biomimetic swimming robot using adaptive frequency oscillators.

PubMed

Alessi, Alessio; Accoto, Dino; Guglielmelli, Eugenio

2015-08-01

Underactuated compliant swimming robots are characterized by a simple mechanical structure, capable to mimic the body undulation of many fish species. One of the design issue for these robots is the generation and control of best performing swimming gaits. In this paper we propose a new controller, based on AFO oscillators, to address this issue. After analyzing the effects of the motion on the robot natural frequencies, we show that the closed loop system is able to generate self-sustained oscillations, at a characteristic frequency, while maximizing swimming velocity.

El Niño$-$Southern Oscillation frequency cascade

DOE PAGES

Stuecker, Malte F.; Jin, Fei -Fei; Timmermann, Axel

2015-10-19

The El Niño$-$Southern Oscillation (ENSO) phenomenon, the most pronounced feature of internally generated climate variability, occurs on interannual timescales and impacts the global climate system through an interaction with the annual cycle. The tight coupling between ENSO and the annual cycle is particularly pronounced over the tropical Western Pacific. In this paper, we show that this nonlinear interaction results in a frequency cascade in the atmospheric circulation, which is characterized by deterministic high-frequency variability on near-annual and subannual timescales. Finally, through climate model experiments and observational analysis, it is documented that a substantial fraction of the anomalous Northwest Pacific anticyclonemore » variability, which is the main atmospheric link between ENSO and the East Asian Monsoon system, can be explained by these interactions and is thus deterministic and potentially predictable.« less

El Niño$-$Southern Oscillation frequency cascade

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stuecker, Malte F.; Jin, Fei -Fei; Timmermann, Axel

The El Niño$-$Southern Oscillation (ENSO) phenomenon, the most pronounced feature of internally generated climate variability, occurs on interannual timescales and impacts the global climate system through an interaction with the annual cycle. The tight coupling between ENSO and the annual cycle is particularly pronounced over the tropical Western Pacific. In this paper, we show that this nonlinear interaction results in a frequency cascade in the atmospheric circulation, which is characterized by deterministic high-frequency variability on near-annual and subannual timescales. Finally, through climate model experiments and observational analysis, it is documented that a substantial fraction of the anomalous Northwest Pacific anticyclonemore » variability, which is the main atmospheric link between ENSO and the East Asian Monsoon system, can be explained by these interactions and is thus deterministic and potentially predictable.« less

Frequency hopping due to acousto-electric interaction in ZnO based surface acoustic wave oscillator

NASA Astrophysics Data System (ADS)

Dasgupta, Daipayan; Sreenivas, K.

2011-08-01

A 36 MHz surface acoustic wave delay line based oscillator has been used to study the effect of acousto-electric interaction due to photo generated charge carriers in rf sputtered ZnO film under UV illumination (λ = 365 nm, 20-100 μW/cm2). Design aspects for developing a delay line based SAW oscillator are specified. The observed linear downshift in frequency (2.2 to 19.0 kHz) with varying UV intensity (20-100 μW/cm2) is related to the fractional velocity change due to acousto-electric interaction. UV illumination level of 100 μW/cm2 leads to a characteristic frequency hopping behavior arising due to a change in the oscillation criteria, and is attributed to the complex interplay between the increased attenuation and velocity shift.

Low-frequency, self-sustained oscillations in inductively coupled plasmas used for optical pumping

DOE Office of Scientific and Technical Information (OSTI.GOV)

Coffer, J.; Encalada, N.; Huang, M.

We have investigated very low frequency, on the order of one hertz, self-pulsing in alkali-metal inductively-coupled plasmas (i.e., rf-discharge lamps). This self-pulsing has the potential to significantly vary signal-to-noise ratios and (via the ac-Stark shift) resonant frequencies in optically pumped atomic clocks and magnetometers (e.g., the atomic clocks now flying on GPS and Galileo global navigation system satellites). The phenomenon arises from a nonlinear interaction between the atomic physics of radiation trapping and the plasma's electrical nature. To explain the effect, we have developed an evaporation/condensation theory (EC theory) of the self-pulsing phenomenon.

Aspects of neutrino oscillation in alternative gravity theories

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chakraborty, Sumanta, E-mail: sumantac.physics@gmail.com

2015-10-01

Neutrino spin and flavour oscillation in curved spacetime have been studied for the most general static spherically symmetric configuration. Having exploited the spherical symmetry we have confined ourselves to the equatorial plane in order to determine the spin and flavour oscillation frequency in this general set-up. Using the symmetry properties we have derived spin oscillation frequency for neutrino moving along a geodesic or in a circular orbit. Starting from the expression of neutrino spin oscillation frequency we have shown that even in this general context, in high energy limit the spin oscillation frequency for neutrino moving along circular orbit vanishes.more » We have verified previous results along this line by transforming to Schwarzschild coordinates under appropriate limit. This finally lends itself to the probability of neutrino helicity flip which turns out to be non-zero. While for neutrino flavour oscillation we have derived general results for oscillation phase, which subsequently have been applied to three different gravity theories. One, of them appears as low-energy approximation to string theory, where we have an additional field, namely, dilaton field coupled to Maxwell field tensor. This yields a realization of Reissner-Nordström solution in string theory at low-energy. Next one corresponds to generalization of Schwarzschild solution by introduction of quadratic curvature terms of all possible form to the Einstein-Hilbert action. Finally, we have also discussed regular black hole solutions. In all these cases the flavour oscillation probabilities can be determined for solar neutrinos and thus can be used to put bounds on the parameters of these gravity theories. While for spin oscillation probability, we have considered two cases, Gauss-Bonnet term added to the Einstein-Hilbert action and the f(R) gravity theory. In both these cases we could impose bounds on the parameters which are consistent with previous considerations. In a

Plasma oscillations in a 6-kW magnetically shielded Hall thruster

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jorns, Benjamin A., E-mail: benjamin.a.jorns@jpl.nasa.gov; Hofer, Richard R.

2014-05-15

Plasma oscillations from 0–100 kHz in a 6-kW magnetically shielded Hall thruster are experimentally characterized with a high-speed, optical camera. Two modes are identified at 7–12 kHz and 70–90 kHz. The low frequency mode is found to be azimuthally uniform across the thruster face, while the high frequency oscillation is peaked close to the centerline-mounted cathode with an m = 1 azimuthal dependence. An analysis of these results in the context of wave-based theory suggests that the low frequency wave is the breathing mode oscillation, while the higher frequency mode is gradient-driven. The effect of these oscillations on thruster operation is examined through an analysismore » of thruster discharge current and a comparison with published observations from an unshielded variant of the thruster. Most notably, it is found that although the oscillation spectra of the two thrusters are different, they exhibit nearly identical steady-state behavior.« less

Low frequency noise fiber delay stabilized laser with reduced sensitivity to acceleration

NASA Astrophysics Data System (ADS)

Argence, B.; Clivati, C.; Dournaux, J.-L.; Holleville, D.; Faure, B.; Lemonde, P.; Santarelli, G.

2017-11-01

Lasers with sub-hertz line-width and fractional frequency instability around 1×10-15 for 0.1 s to 10 s averaging time are currently realized by locking onto an ultra-stable Fabry-Perot cavity using the Pound-Drever-Hall method. This powerful method requires tight alignment of free space optical components, precise polarization adjustment and spatial mode matching. To circumvent these issues, we use an all-fiber Michelson interferometer with a long fiber spool as a frequency reference and a heterodyne detection technique with a fibered acousto optical modulator (AOM)1. At low Fourier frequencies, the frequency noise of our system is mainly limited by mechanical vibrations, an issue that has already been explored in the field of optoelectronic oscillators.2,3,4

The Cerebellar Mossy Fiber Synapse as a Model for High-Frequency Transmission in the Mammalian CNS.

PubMed

Delvendahl, Igor; Hallermann, Stefan

2016-11-01

The speed of neuronal information processing depends on neuronal firing frequency. Here, we describe the evolutionary advantages and ubiquitous occurrence of high-frequency firing within the mammalian nervous system in general. The highest firing frequencies so far have been observed at the cerebellar mossy fiber to granule cell synapse. The mechanisms enabling high-frequency transmission at this synapse are reviewed and compared with other synapses. Finally, information coding of high-frequency signals at the mossy fiber synapse is discussed. The exceptionally high firing frequencies and amenability to high-resolution technical approaches both in vitro and in vivo establish the cerebellar mossy fiber synapse as an attractive model to investigate high-frequency signaling from the molecular up to the network level. Copyright © 2016 Elsevier Ltd. All rights reserved.

Cryogenic Pound Circuits for Cryogenic Sapphire Oscillators

NASA Technical Reports Server (NTRS)

Dick, G. John; Wang, Rabi

2006-01-01

Two modern cryogenic variants of the Pound circuit have been devised to increase the frequency stability of microwave oscillators that include cryogenic sapphire-filled cavity resonators. The original Pound circuit is a microwave frequency discriminator that provides feedback to stabilize a voltage-controlled microwave oscillator with respect to an associated cavity resonator. In the present cryogenic Pound circuits, the active microwave devices are implemented by use of state-of-the-art commercially available tunnel diodes that exhibit low flicker noise (required for high frequency stability) and function well at low temperatures and at frequencies up to several tens of gigahertz. While tunnel diodes are inherently operable as amplitude detectors and amplitude modulators, they cannot, by themselves, induce significant phase modulation. Therefore, each of the present cryogenic Pound circuits includes passive circuitry that transforms the AM into the required PM. Each circuit also contains an AM detector that is used to sample the microwave signal at the input terminal of the high-Q resonator for the purpose of verifying the desired AM null at this point. Finally, each circuit contains a Pound signal detector that puts out a signal, at the modulation frequency, having an amplitude proportional to the frequency error in the input signal. High frequency stability is obtained by processing this output signal into feedback to a voltage-controlled oscillator to continuously correct the frequency error in the input signal.

Human gamma-frequency oscillations associated with attention and memory.

PubMed

Jensen, Ole; Kaiser, Jochen; Lachaux, Jean-Philippe

2007-07-01

Both theoretical and experimental animal work supports the hypothesis that transient oscillatory synchronization of neuronal assemblies at gamma frequencies (30-100 Hz) is closely associated with sensory processing. Recent data from recordings in animals and humans have suggested that gamma-frequency activity also has an important role in attention and both working and long-term memory. The involvement of gamma-band synchronization in various cognitive paradigms in humans is currently being investigated using intracranial and high-density electro- and magnetoencephalography recordings. Here, we discuss recent findings demonstrating human gamma-frequency activity associated with attention and memory in both sensory and non-sensory areas. Because oscillatory gamma-frequency activity has an important role in neuronal communication and synaptic plasticity, it could provide a key for understanding neuronal processing in both local and distributed cortical networks engaged in complex cognitive functions. This review is part of the INMED/TINS special issue Physiogenic and pathogenic oscillations: the beauty and the beast, based on presentations at the annual INMED/TINS symposium (http://inmednet.com).

Detection of High-Frequency Oscillations and Damping from Multi-slit Spectroscopic Observations of the Corona

NASA Astrophysics Data System (ADS)

Samanta, T.; Singh, J.; Sindhuja, G.; Banerjee, D.

2016-01-01

During the total solar eclipse of 11 July 2010, multi-slit spectroscopic observations of the solar corona were performed from Easter Island, Chile. To search for high-frequency waves, observations were taken at a high cadence in the green line at 5303 Å that is due to [Fe xiv] and the red line at 6374 Å that is due to [Fe x]. The data were analyzed to study the periodic variations in intensity, Doppler velocity, and line width using wavelet analysis. The data with high spectral and temporal resolution enabled us to study the rapid dynamical changes within coronal structures. We find that at certain locations, each parameter shows significant oscillation with periods ranging from 6 - 25 s. For the first time, we were able to detect damping of high-frequency oscillations with periods of about 10 s. If the observed damped oscillations are due to magnetohydrodynamic waves, then they can contribute significantly to the heating of the corona. From a statistical study we try to characterize the nature of the observed oscillations while considering the distribution of power in different line parameters.

High-frequency large-amplitude oscillations of a non-isothermal N/S boundary

NASA Astrophysics Data System (ADS)

Bezuglyj, A. I.; Shklovskij, V. A.

2016-10-01

Within the framework of a phenomenological approach based on the heat balance equation and the current dependence of the critical temperature of the superconductor, the effect of high-frequency current of large amplitude and arbitrary waveform on the non-isothermal balance of an oscillating N/S interface in a long superconductor was studied. Self-consistent average temperature field of the rapidly oscillating non-isothermal N/S boundary (heat kink) was introduced, which allowed us to go beyond the well-known concept of mean-square heating and consider the effect of the current waveform. With regard to experiments on the effects of high-power microwave radiation on the current-voltage (IV) characteristics of superconducting films, their classification was performed and the families of IV curves of inhomogeneous superconductors carrying a current containing a high-frequency component of large amplitude. Several IV curves exhibited a hysteresis of thermal nature.

Exoskeleton control for lower-extremity assistance based on adaptive frequency oscillators: adaptation of muscle activation and movement frequency.

PubMed

Aguirre-Ollinger, Gabriel

2015-01-01

In this article, we analyze a novel strategy for assisting the lower extremities based on adaptive frequency oscillators. Our aim is to use the control algorithm presented here as a building block for the control of powered lower-limb exoskeletons. The algorithm assists cyclic movements of the human extremities by synchronizing actuator torques with the estimated net torque exerted by the muscles. Synchronization is produced by a nonlinear dynamical system combining an adaptive frequency oscillator with a form of adaptive Fourier analysis. The system extracts, in real time, the fundamental frequency component of the net muscle torque acting on a specific joint. Said component, nearly sinusoidal in shape, is the basis for the assistive torque waveform delivered by the exoskeleton. The action of the exoskeleton can be interpreted as a virtual reduction in the mechanical impedance of the leg. We studied the ability of human subjects to adapt their muscle activation to the assistive torque. Ten subjects swung their extended leg while coupled to a stationary hip joint exoskeleton. The experiment yielded a significant decrease, with respect to unassisted movement, of the activation levels of an agonist/antagonist pair of muscles controlling the hip joint's motion, which suggests the exoskeleton control has potential for assisting human gait. A moderate increase in swing frequency was observed as well. We theorize that the increase in frequency can be explained by the impedance model of the assisted leg. Per this model, subjects adjust their swing frequency in order to control the amount of reduction in net muscle torque. © IMechE 2015.

High repetition frequency PPMgOLN mid-infrared optical parametric oscillator

NASA Astrophysics Data System (ADS)

Liu, J.; Liu, Q.; Yan, X.; Chen, H.; Gong, M.

2010-09-01

A mid-infrared optical parametric oscillator (OPO) with the idler wavelengths of 3591 nm, 3384 nm, and 3164 nm at the repetition of 76.8 kHz is reported, and a high repetition frequency acousto-optic Q-switched Nd:YVO4 laser is used as the pump source. The OPO is designed as an external non-colinear single-resonator optical parametric oscillator. When the power of the pump light is 25.1 W, the idler with the wavelength of 3164 nm and the power of 4.3 W is generated. The corresponding signal light is 1603 nm with the power of 3.1 W. The efficiency from 1064 nm to 3160 nm can reach as high as 17.1%, and the efficiency of the OPO is 29.5%.

Electric-field assisted spin torque nano-oscillator and binary frequency shift keying modulation

NASA Astrophysics Data System (ADS)

Zhang, Xiangli; Chen, Hao-Hsuan; Zhang, Zongzhi; Liu, Yaowen

2018-04-01

Electric-controlled magnetization precession introduces technologically relevant possibility for developing spin torque nano-oscillators (STNO) with potential applications in microwave emission. Using the perpendicularly magnetized magnetic tunnel junction (MTJ), we show that the magnetization oscillation frequency can be tuned by the co-action of electric field and spin polarized current. The dynamical phase diagram of MTJ-based STNO is analytically predicted through coordinate transformation from the laboratory frame to the rotation frame, by which the nonstationary out-of-plane magnetization precession process is therefore transformed into the stationary process in the rotation frame. Furthermore, using this STNO as a microwave source, we numerically demonstrate that the bit signal can be transmitted by a binary frequency shift keying (BFSK) modulation technique. The BFSK scheme shows good modulation features with no transient state.

Impact of excitation waveform on the frequency stability of electrostatically-actuated micro-electromechanical oscillators

NASA Astrophysics Data System (ADS)

Juillard, J.; Brenes, A.

2018-05-01

In this paper, the frequency stability of high-Q electrostatically-actuated MEMS oscillators with cubic restoring forces, and its relation with the amplitude, the phase and the shape of the excitation waveform, is studied. The influence on close-to-the carrier frequency noise of additive processes (such as thermomechanical noise) or parametric processes (bias voltage fluctuations, feedback phase fluctuations, feedback level fluctuations) is taken into account. It is shown that the optimal operating conditions of electrostatically-actuated MEMS oscillators are highly waveform-dependent, a factor that is largely overlooked in the existing literature. This simulation-based study covers the cases of harmonic and pulsed excitation of a parallel-plate capacitive MEMS resonator.

Dynamics of the solar chromosphere. I - Long-period network oscillations

NASA Technical Reports Server (NTRS)

Lites, B. W.; Rutten, R. J.; Kalkofen, W.

1993-01-01

We analyze differences in solar oscillations between the chromospheric network and internetwork regions from a 1 hr sequence of spectrograms of a quiet region near disk center. The spectrograms contain Ca II H, Ca I 422.7 nm, and various Fe I blends in the Ca II H wing. They permit vertical tracing of oscillations throughout the photosphere and into the low chromosphere. We find that the rms amplitude of Ca II H line center Doppler fluctuations is about 1.5 km/s for both network and internetwork, but that the character of the oscillations differs markedly in these two regions. Within internetwork areas the chromospheric velocity power spectrum is dominated by oscillations with frequencies at and above the acoustic cutoff frequency. They are well correlated with the oscillations in the underlying photosphere, but they are much reduced in the network. In contrast, the network Ca II H line center velocity and intensity power spectra are dominated by low-frequency oscillations with periods of 5-20 min. Their signature is much clearer in our Ca II H line center measurements than in previously used diagnostics which are contaminated by signals from deeper layers. We find that these long-period oscillations are not correlated with underlying photospheric disturbances, and we discuss their nature.

In vivo mouse inferior olive neurons exhibit heterogeneous subthreshold oscillations and spiking patterns

PubMed Central

Khosrovani, S.; Van Der Giessen, R. S.; De Zeeuw, C. I.; De Jeu, M. T. G.

2007-01-01

In vitro whole-cell recordings of the inferior olive have demonstrated that its neurons are electrotonically coupled and have a tendency to oscillate. However, it remains to be shown to what extent subthreshold oscillations do indeed occur in the inferior olive in vivo and whether its spatiotemporal firing pattern may be dynamically generated by including or excluding different types of oscillatory neurons. Here, we did whole-cell recordings of olivary neurons in vivo to investigate the relation between their subthreshold activities and their spiking behavior in an intact brain. The vast majority of neurons (85%) showed subthreshold oscillatory activities. The frequencies of these subthreshold oscillations were used to distinguish four main olivary subtypes by statistical means. Type I showed both sinusoidal subthreshold oscillations (SSTOs) and low-threshold Ca2+ oscillations (LTOs) (16%); type II showed only sinusoidal subthreshold oscillations (13%); type III showed only low-threshold Ca2+ oscillations (56%); and type IV did not reveal any subthreshold oscillations (15%). These subthreshold oscillation frequencies were strongly correlated with the frequencies of preferred spiking. The frequency characteristics of the subthreshold oscillations and spiking behavior of virtually all olivary neurons were stable throughout the recordings. However, the occurrence of spontaneous or evoked action potentials modified the subthreshold oscillation by resetting the phase of its peak toward 90°. Together, these findings indicate that the inferior olive in intact mammals offers a rich repertoire of different neurons with relatively stable frequency settings, which can be used to generate and reset temporal firing patterns in a dynamically coupled ensemble. PMID:17895389

Frequency-agile terahertz-wave parametric oscillator in a ring-cavity configuration.

PubMed

Minamide, Hiroaki; Ikari, Tomofumi; Ito, Hiromasa

2009-12-01

We demonstrate a frequency-agile terahertz wave parametric oscillator (TPO) in a ring-cavity configuration (ring-TPO). The TPO consists of three mirrors and a MgO:LiNbO(3) crystal under noncollinear phase-matching conditions. A novel, fast frequency-tuning method was realized by controlling a mirror of the three-mirror ring cavity. The wide tuning range between 0.93 and 2.7 THz was accomplished. For first demonstration using the ring-TPO, terahertz spectroscopy was performed as the verification of the frequency-agile performance, measuring the transmission spectrum of the monosaccharide glucose. The spectrum was obtained within about 8 s in good comparison to those of Fourier transform infrared spectrometer.

Dissociation of frontal-midline delta-theta and posterior alpha oscillations: A mobile EEG study.

PubMed

Liang, Mingli; Starrett, Michael J; Ekstrom, Arne D

2018-04-22

Numerous reports have demonstrated low-frequency oscillations during navigation using invasive recordings in the hippocampus of both rats and human patients. Given evidence, in some cases, of low-frequency synchronization between midline cortex and hippocampus, it is also possible that low-frequency movement-related oscillations manifest in healthy human neocortex. However, this possibility remains largely unexplored, in part due to the difficulties of coupling free ambulation and effective scalp EEG recordings. In the current study, participants freely ambulated on an omnidirectional treadmill and explored an immersive virtual reality city rendered on a head-mounted display while undergoing simultaneous wireless scalp EEG recordings. We found that frontal-midline (FM) delta-theta (2-7.21 Hz) oscillations increased during movement compared to standing still periods, consistent with a role in navigation. In contrast, posterior alpha (8.32-12.76 Hz) oscillations were suppressed in the presence of visual input, independent of movement. Our findings suggest that FM delta-theta and posterior alpha oscillations arise at independent frequencies, under complementary behavioral conditions, and, at least for FM delta-theta oscillations, at independent recordings sites. Together, our findings support a double dissociation between movement-related FM delta-theta and resting-related posterior alpha oscillations. Our study thus provides novel evidence that FM delta-theta oscillations arise, in part, from real-world ambulation, and are functionally independent from posterior alpha oscillations. © 2018 Society for Psychophysiological Research.

Effect of artificially lengthened vocal tract on vocal fold oscillation's fundamental frequency.

PubMed

Hanamitsu, Masakazu; Kataoka, Hideyuki

2004-06-01

The fundamental frequency of vocal fold oscillation (F(0)) is controlled by laryngeal mechanics and aerodynamic properties. F(0) change per unit change of transglottal pressure (dF/dP) using a shutter valve has been studied and found to have nonlinear, V-shaped relationship with F(0). On the other hand, the vocal tract is also known to affect vocal fold oscillation. This study examined the effect of artificially lengthened vocal tract length on dF/dP. dF/dP was measured in six men using two mouthpieces of different lengths. The dF/dP graph for the longer vocal tract was shifted leftward relative to the shorter one. Using the one-mass model, the nadir of the "V" on the dF/dP graph was strongly influenced by the resonance around the first formant frequency. However, a more precise model is needed to account for the effects of viscosity and turbulence.

Direct observation of surface-state thermal oscillations in SmB6 oscillators

NASA Astrophysics Data System (ADS)

Casas, Brian; Stern, Alex; Efimkin, Dmitry K.; Fisk, Zachary; Xia, Jing

2018-01-01

SmB6 is a mixed valence Kondo insulator that exhibits a sharp increase in resistance following an activated behavior that levels off and saturates below 4 K. This behavior can be explained by the proposal of SmB6 representing a new state of matter, a topological Kondo insulator, in which a Kondo gap is developed, and topologically protected surface conduction dominates low-temperature transport. Exploiting its nonlinear dynamics, a tunable SmB6 oscillator device was recently demonstrated, where a small dc current generates large oscillating voltages at frequencies from a few Hz to hundreds of MHz. This behavior was explained by a theoretical model describing the thermal and electronic dynamics of coupled surface and bulk states. However, a crucial aspect of this model, the predicted temperature oscillation in the surface state, has not been experimentally observed to date. This is largely due to the technical difficulty of detecting an oscillating temperature of the very thin surface state. Here we report direct measurements of the time-dependent surface-state temperature in SmB6 with a RuO2 microthermometer. Our results agree quantitatively with the theoretically simulated temperature waveform, and hence support the validity of the oscillator model, which will provide accurate theoretical guidance for developing future SmB6 oscillators at higher frequencies.

The role of high-frequency oscillations in epilepsy surgery planning.

PubMed

Gloss, David; Nolan, Sarah J; Staba, Richard

2014-01-15

Epilepsy is a serious brain disorder characterized by recurrent unprovoked seizures. Approximately two-thirds of seizures can be controlled with antiepileptic medications (Kwan 2000). For some of the others, surgery can completely eliminate or significantly reduce the occurrence of disabling seizures. Localization of epileptogenic areas for resective surgery is far from perfect, and new tools are being investigated to more accurately localize the epileptogenic zone (the zone of the brain where the seizures begin) and improve the likelihood of freedom from postsurgical seizures. Recordings of pathological high-frequency oscillations (HFOs) may be one such tool. To assess the ability of HFOs to improve the outcomes of epilepsy surgery by helping to identify more accurately the epileptogenic areas of the brain. We searched the Cochrane Epilepsy Group Specialized Register (15 April 2013), the Cochrane Central Register of Controlled Trials (CENTRAL) in The Cochrane Library (2013, Issue 3), MEDLINE (Ovid) (1946 to 15 April 2013), CINAHL (EBSCOhost) (15 April 2013), Web of Knowledge (Thomson Reuters) (15 April 2013), www.clinicaltrials.gov (15 April 2013), and the World Health Organization International Clinical Trials Registry Platform (15 April 2013). We included studies that provided information on the outcomes of epilepsy surgery at at least six months and which used high-frequency oscillations in making decisions about epilepsy surgery. The primary outcome of the review was the Engel Class Outcome System. Secondary outcomes were responder rate, International League Against Epilepsy (ILAE) epilepsy surgery outcome, frequency of adverse events from any source and quality of life outcomes. We intended to analyse outcomes via an aggregated data fixed-effect model meta-analysis. Two studies met the inclusion criteria. Both studies were small non-randomised trials, with no control group and no blinding. The quality of evidence for all outcomes was very low. The combination

Carrier-envelope frequency stabilization of a Ti:sapphire oscillator using different pump lasers.

PubMed

Vernaleken, Andreas; Schmidt, Bernhard; Wolferstetter, Martin; Hänsch, Theodor W; Holzwarth, Ronald; Hommelhoff, Peter

2012-07-30

We investigate the suitability of various commercially available pump lasers for operation with a carrier-envelope offset frequency stabilized Ti:sapphire oscillator. Although the tested pump lasers differ in their setup and properties (e.g., single vs. multi-mode), we find that they are all well-suited for the purpose. The residual rms phase noise (integrated between 20 Hz and 5 MHz) of the stabilized oscillator is found to be below 160 mrad with each pump laser, corresponding to less than 1/40 of an optical cycle. Differences in performance vary slightly. In particular, our results indicate that the latest generation of multi-mode pump lasers can be used for applications where precise phase control of the oscillator is strictly required.

A method for the topographical identification and quantification of high frequency oscillations in intracranial electroencephalography recordings

PubMed Central

Waldman, Zachary J.; Shimamoto, Shoichi; Song, Inkyung; Orosz, Iren; Bragin, Anatol; Fried, Itzhak; Engel, Jerome; Staba, Richard; Sperling, Michael R.; Weiss, Shennan A.

2018-01-01

Objective To develop a reliable software method using a topographic analysis of time-frequency plots to distinguish ripple (80–200 Hz) oscillations that are often associated with EEG sharp waves or spikes (RonS) from sinusoid-like waveforms that appear as ripples but correspond with digital filtering of sharp transients contained in the wide bandwidth EEG. Methods A custom algorithm distinguished true from false ripples in one second intracranial EEG (iEEG) recordings using wavelet convolution, identifying contours of isopower, and categorizing these contours into sets of open or closed loop groups. The spectral and temporal features of candidate groups were used to classify the ripple, and determine its duration, frequency, and power. Verification of detector accuracy was performed on the basis of simulations, and visual inspection of the original and band-pass filtered signals. Results The detector could distinguish simulated true from false ripple on spikes (RonS). Among 2934 visually verified trials of iEEG recordings and spectrograms exhibiting RonS the accuracy of the detector was 88.5% with a sensitivity of 81.8% and a specificity of 95.2%. The precision was 94.5% and the negative predictive value was 84.0% (N = 12). Among, 1,370 trials of iEEG recording exhibiting RonS that were reviewed blindly without spectrograms the accuracy of the detector was 68.0%, with kappa equal to 0.01 ± 0.03. The detector successfully distinguished ripple from high spectral frequency ‘fast ripple’ oscillations (200–600 Hz), and characterize ripple duration and spectral frequency and power. The detector was confounded by brief bursts of gamma (30–80 Hz) activity in 7.31 ± 6.09% of trials, and in 30.2 ± 14.4% of the true RonS detections ripple duration was underestimated. Conclusions Characterizing the topographic features of a time-frequency plot generated by wavelet convolution is useful for distinguishing true oscillations from false oscillations generated by

Interplay of intrinsic and synaptic conductances in the generation of high-frequency oscillations in interneuronal networks with irregular spiking.

PubMed

Baroni, Fabiano; Burkitt, Anthony N; Grayden, David B

2014-05-01

High-frequency oscillations (above 30 Hz) have been observed in sensory and higher-order brain areas, and are believed to constitute a general hallmark of functional neuronal activation. Fast inhibition in interneuronal networks has been suggested as a general mechanism for the generation of high-frequency oscillations. Certain classes of interneurons exhibit subthreshold oscillations, but the effect of this intrinsic neuronal property on the population rhythm is not completely understood. We study the influence of intrinsic damped subthreshold oscillations in the emergence of collective high-frequency oscillations, and elucidate the dynamical mechanisms that underlie this phenomenon. We simulate neuronal networks composed of either Integrate-and-Fire (IF) or Generalized Integrate-and-Fire (GIF) neurons. The IF model displays purely passive subthreshold dynamics, while the GIF model exhibits subthreshold damped oscillations. Individual neurons receive inhibitory synaptic currents mediated by spiking activity in their neighbors as well as noisy synaptic bombardment, and fire irregularly at a lower rate than population frequency. We identify three factors that affect the influence of single-neuron properties on synchronization mediated by inhibition: i) the firing rate response to the noisy background input, ii) the membrane potential distribution, and iii) the shape of Inhibitory Post-Synaptic Potentials (IPSPs). For hyperpolarizing inhibition, the GIF IPSP profile (factor iii)) exhibits post-inhibitory rebound, which induces a coherent spike-mediated depolarization across cells that greatly facilitates synchronous oscillations. This effect dominates the network dynamics, hence GIF networks display stronger oscillations than IF networks. However, the restorative current in the GIF neuron lowers firing rates and narrows the membrane potential distribution (factors i) and ii), respectively), which tend to decrease synchrony. If inhibition is shunting instead of

Interplay of Intrinsic and Synaptic Conductances in the Generation of High-Frequency Oscillations in Interneuronal Networks with Irregular Spiking

PubMed Central

Baroni, Fabiano; Burkitt, Anthony N.; Grayden, David B.

2014-01-01

High-frequency oscillations (above 30 Hz) have been observed in sensory and higher-order brain areas, and are believed to constitute a general hallmark of functional neuronal activation. Fast inhibition in interneuronal networks has been suggested as a general mechanism for the generation of high-frequency oscillations. Certain classes of interneurons exhibit subthreshold oscillations, but the effect of this intrinsic neuronal property on the population rhythm is not completely understood. We study the influence of intrinsic damped subthreshold oscillations in the emergence of collective high-frequency oscillations, and elucidate the dynamical mechanisms that underlie this phenomenon. We simulate neuronal networks composed of either Integrate-and-Fire (IF) or Generalized Integrate-and-Fire (GIF) neurons. The IF model displays purely passive subthreshold dynamics, while the GIF model exhibits subthreshold damped oscillations. Individual neurons receive inhibitory synaptic currents mediated by spiking activity in their neighbors as well as noisy synaptic bombardment, and fire irregularly at a lower rate than population frequency. We identify three factors that affect the influence of single-neuron properties on synchronization mediated by inhibition: i) the firing rate response to the noisy background input, ii) the membrane potential distribution, and iii) the shape of Inhibitory Post-Synaptic Potentials (IPSPs). For hyperpolarizing inhibition, the GIF IPSP profile (factor iii)) exhibits post-inhibitory rebound, which induces a coherent spike-mediated depolarization across cells that greatly facilitates synchronous oscillations. This effect dominates the network dynamics, hence GIF networks display stronger oscillations than IF networks. However, the restorative current in the GIF neuron lowers firing rates and narrows the membrane potential distribution (factors i) and ii), respectively), which tend to decrease synchrony. If inhibition is shunting instead of

Flow around circular cylinder oscillating at low Keulegan-Carpenter number

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sunahara, Shunji; Kinoshita, Takeshi

1994-12-31

This paper shows experimental results of hydrodynamic forces acting on a vertical circular cylinder oscillating sinusoidally at low frequencies in the still water and results of the flow visualization, to examine the flow around a circular cylinder, particularly the lift forces at low Keulegan-Carpenter number Kc. The instability of streaked flow of which section is mushroom shape is observed by flow visualization, and the flows are asymmetrical in some cases. The asymmetrical streaked flow may have a close relationship to the lift force at low Kc, Kc {le} 4 or 5. Asymmetrical mushroom vortex ring is visible for Kc {le}more » 1. The mushroom vortex ring is symmetrical, or the streaks of the rings arrange themselves alternately for 1 {le} Kc {le} 1.5. A clear ring of mushroom vortices is not formed due to diffusion of dye sheets, though a flow streaked with mushroom vortices is visible for 1.5 {le} Kc {le} 2.5 and for Kc {ge} 2.5 the flow is almost turbulent.« less

How to Distinguish Neutron Star and Black Hole X-ray Binaries? Spectral Index and Quasi-Periodic Oscillation Frequency Correlation

NASA Technical Reports Server (NTRS)

Titarchuk, Lev; Shaposhnikov, Nickolai

2005-01-01

Recent studies have revealed strong correlations between 1-10 Hz frequencies of quasiperiodic oscillations (QPOs) and the spectral power law index of several Black Hole (BH) candidate sources when seen in the low/hard state, the steep power-law (soft) state, and in transition between these states. In the soft state these index-QPO frequency correlations show a saturation of the photon index GAMMA approximately equal to 2.7 at high values of the low frequency nu(sub L). This saturation effect was previously identified as a black hole signature. In this paper we argue that this saturation does not occur, at least for one neutron star (NS) source 4U 1728-34, for which the index GAMMA monotonically increases with nu(sub L) to the values of 6 and higher. We base this conclusion on our analysis of approximately 1.5 Msec of RXTE archival data for 4U 1728-34. We reveal the spectral evolution of the Comptonized blackbody spectra when the source transitions from the hard to soft states. The hard state spectrum is a typical thermal Comptonization spectrum of the soft photons which originate in the disk and the NS outer photospheric layers. The hard state photon index is GAMMA approximately 2. The soft state spectrum consists of two blackbody components which are only slightly Comptonized. Thus we can claim (as expected from theory) that in NS sources thermal equilibrium is established for the soft state. To the contrary in BH sources, the equilibrium is never established due to the presence of the BH horizon. The emergent BH spectrum, even in the high/soft state, has a power law component. We also identify the low QPO frequency nu(sub L) as a fundamental frequency of the quasi-spherical component of the transition layer (presumably related to the corona and the NS and disk magnetic closed field lines). The lower frequency nu(sub SL) is identified as the frequency of oscillations of a quasi-cylindrical configuration of the TL (presumably related to the NS and disk magnetic

Reduced event-related low frequency EEG activity in patients with early onset schizophrenia and their unaffected siblings.

PubMed

Simmonite, Molly; Bates, Alan Thomas; Groom, Madeleine; Hollis, Chris; Liddle, Peter Francis

2015-04-30

Low-frequency oscillations in the electroencephalogram (EEG) have been found to be abnormal in patients with schizophrenia. It is unclear, however, whether these abnormalities are related to severity of illness or are a marker for risk. This study investigated total and evoked theta and delta activity in schizophrenia patients, unaffected siblings, and healthy controls (HCs). EEG data were recorded whilst 24 individuals with schizophrenia, 26 unaffected siblings of individuals with schizophrenia and 26 healthy control participants completed a Go/No-Go task. Event-related total activity and evoked theta and delta activity were calculated for correct hits (CH), failed inhibitions (FI) and correct inhibitions (CI) trials. Patients displayed significantly less total delta, evoked delta, total theta and evoked theta activity when compared with healthy controls. Unaffected siblings displayed abnormalities of evoked delta, but other measures were similar to those in control participants. The findings of this study add to evidence that abnormal low-frequency EEG oscillations contribute to impairments in information processing seen in schizophrenia. These findings also suggest abnormal evoked delta oscillations are associated with an increased familial risk of developing the disorder. Copyright © 2015. Published by Elsevier Ireland Ltd.

HIGH POWER PULSED OSCILLATOR

DOEpatents

Singer, S.; Neher, L.K.

1957-09-24

A high powered, radio frequency pulse oscillator is described for generating trains of oscillations at the instant an input direct voltage is impressed, or immediately upon application of a light pulse. In one embodiment, the pulse oscillator comprises a photo-multiplier tube with the cathode connected to the first dynode by means of a resistor, and adjacent dynodes are connected to each other through adjustable resistors. The ohmage of the resistors progressively increases from a very low value for resistors adjacent the cathode to a high value adjacent the plate, the last dynode. Oscillation occurs with this circuit when a high negative voltage pulse is applied to the cathode and the photo cathode is bombarded. Another embodiment adds capacitors at the resistor connection points of the above circuit to increase the duration of the oscillator train.

A frequency doubled pressure-tunable oscillator-amplifier dye laser system

NASA Technical Reports Server (NTRS)

Moriarty, A.; Heaps, W.; Davis, D. D.

1976-01-01

A tunable high-repetition-rate oscillator-amplifier dye-laser system is reported. The dye laser described was longitudinally pumped with the second harmonic of a Nd-YAG laser operating at 10 Hz. Using three Faraday-Perot etalons and pressure tuning, a maximum fundamental output power of the order of 6 MW with a corresponding spectral width of less than 0.003 nm at 564 nm was obtained. The fundamental at 564 nm was frequency doubled to give a maximum power level of 0.6 MW of second-harmonic output power with a spectral width less than 0.0015 nm at 282 nm. Frequency stability could be maintained to within approximately 15% of the line-width.

Relationships between hippocampal sharp waves, ripples and fast gamma oscillation: influence of dentate and entorhinal cortical activity

PubMed Central

Sullivan, David; Csicsvari, Jozsef; Mizuseki, Kenji; Montgomery, Sean; Diba, Kamran; Buzsáki, György

2011-01-01

Summary Hippocampal sharp waves (SPW) and associated fast (‘ripple’) oscillations in the CA1 region are among the most synchronous physiological patterns in the mammalian brain. Using two-dimensional arrays of electrodes for recording local field potentials and unit discharges in freely moving rats, we studied the emergence of ripple oscillations (140–220 Hz) and compared their origin and cellular-synaptic mechanisms with fast gamma oscillations (90–140 Hz). We show that (a) hippocampal SPW-Rs and fast gamma oscillations are quantitatively distinct patterns but involve the same networks and share similar mechanisms, (b) both the frequency and magnitude of fast oscillations is positively correlated with the magnitude of SPWs, (c) during both ripples and fast gamma oscillations the frequency of network oscillation is higher in CA1 than in CA3, (d) SPWs and associated firing of neurons are synchronous in the dorsal hippocampus and dorso-medial entorhinal cortex but ripples are confined to the CA1 pyramidal layer and its downstream targets and (e) the emergence of CA3 population bursts, a prerequisite for SPW-ripples, is biased by activity patterns in the dentate gyrus and entorhinal cortex, with highest probability of ripples associated with an ‘optimum’ level of dentate gamma power. We hypothesize that each hippocampal subnetwork possesses distinct resonant properties, tuned by the magnitude of the excitatory drive. PMID:21653864

Low-noise sub-harmonic injection locked multiloop ring oscillator

NASA Astrophysics Data System (ADS)

Weilin, Xu; Di, Wu; Xueming, Wei; Baolin, Wei; Jihai, Duan; Fadi, Gui

2016-09-01

A three-stage differential voltage-controlled ring oscillator is presented for wide-tuning and low-phase noise requirement of clock and data recovery circuit in ultra wideband (UWB) wireless body area network. To improve the performance of phase noise of delay cell with coarse and fine frequency tuning, injection locked technology together with pseudo differential architecture are adopted. In addition, a multiloop is employed for frequency boosting. Two RVCOs, the standard RVCO without the IL block and the proposed IL RVCO, were fabricated in SMIC 0.18 μm 1P6M Salicide CMOS process. The proposed IL RVCO exhibits a measured phase noise of -112.37 dBc/Hz at 1 MHz offset from the center frequency of 1 GHz, while dissipating a current of 8 mA excluding the buffer from a 1.8-V supply voltage. It shows a 16.07 dB phase noise improvement at 1 MHz offset compared to the standard topology. Project supported by the National Natural Science Foundation of China (No. 61264001), the Guangxi Natural Science Foundation (Nos. 2013GXNSFAA019333, 2015GXNSFAA139301, 2014GXNSFAA118386), the Graduate Education Innovation Program of GUET (No. GDYCSZ201457), the Project of Guangxi Education Department (No. LD14066B) and the High-Level-Innovation Team and Outstanding Scholar Project of Guangxi Higher Education Institutes.

Tympanal spontaneous oscillations reveal mechanisms for the control of amplified frequency in tree crickets

NASA Astrophysics Data System (ADS)

Mhatre, Natasha; Robert, Daniel

2018-05-01

Tree cricket hearing shows all the features of an actively amplified auditory system, particularly spontaneous oscillations (SOs) of the tympanal membrane. As expected from an actively amplified auditory system, SO frequency and the peak frequency in evoked responses as observed in sensitivity spectra are correlated. Sensitivity spectra also show compressive non-linearity at this frequency, i.e. a reduction in peak height and sharpness with increasing stimulus amplitude. Both SO and amplified frequency also change with ambient temperature, allowing the auditory system to maintain a filter that is matched to song frequency. In tree crickets, remarkably, song frequency varies with ambient temperature. Interestingly, active amplification has been reported to be switched ON and OFF. The mechanism of this switch is as yet unknown. In order to gain insights into this switch, we recorded and analysed SOs as the auditory system transitioned from the passive (OFF) state to the active (ON) state. We found that while SO amplitude did not follow a fixed pattern, SO frequency changed during the ON-OFF transition. SOs were first detected above noise levels at low frequencies, sometimes well below the known song frequency range (0.5-1 kHz lower). SO frequency was observed to increase over the next ˜30 minutes, in the absence of any ambient temperature change, before settling at a frequency within the range of conspecific song. We examine the frequency shift in SO spectra with temperature and during the ON/OFF transition and discuss the mechanistic implications. To our knowledge, such modulation of active auditory amplification, and its dynamics are unique amongst auditory animals.

Phase noise analysis of voltage controlled oscillator used in cesium atomic clock

NASA Astrophysics Data System (ADS)

Zhi, Menghui; Tang, Liang; Qiao, Donghai

2017-03-01

Coherent population trapping (CPT) cesium frequency standard plays a significant role in precision guidance of missile and global positioning system (GPS). Low noise 4.596 GHz voltage controlled oscillator (VCO) is an indispensable part of microwave signal source in cesium frequency standard. Low-phase noise is also the most important and difficult performance indicator of VCO. Starting from phase noise analysis method proposed by Leeson, the formulas about the relationship between phase noise of output signal of oscillator feedback model and phase fluctuation spectrum of amplifier, phase noise of oscillator are derived in this paper. Finally, the asymptote model of microwave oscillator is proposed based on the formula derivation. The experiment shows that when the reverse bias voltage of variode is 1.8 V, the designed oscillation frequency of VCO is 4.596 GHz, the power is -1 dBm and the DC power consumption is 19.6 mW. The tendency of phase noise simulation curve and actual test curve conform to asymptote model. The phase noise in 1 and 10 kHz is, respectively, -60.86 and -86.58 dBc/Hz. The significance of the paper lies in determining the main factors influencing oscillator phase noise and providing guiding direction for the design of low-phase noise VCO.

Very low frequency oscillations in the power spectra of heart rate variability during dry supine immersion and exposure to non-hypoxic hypobaria.

PubMed

Tripathi, K K

2011-06-01

The origin of very low frequency (VLF) oscillations in the power spectra of heart rate variability (HRV) is controversial with possible mechanisms involving thermoregulation and/or renin-angiotensin-aldosterone system. Recently, a major contribution from vagal influences has been suggested. The present study investigated the behaviour of VLF (0.004-0.040 Hz) components of HRV power spectra in a group of healthy male volunteers during their exposure to (1) dry, supine, immersion in thermo-neutral water for 6 h (n = 7) and (2) non-hypoxic hypobaria (breathing 40-60% oxygen at 15,000' simulated in a decompression chamber) for 5 h (n = 15). The two manoeuvres are established to increase vagal outflow. During both the manoeuvres, all the frequency domain indices of HRV exhibited a significant increase. Increase in HRV was much more than that in the R-R interval. At 6 h of immersion, the R-R interval increased by ∼ 15% but the total power increased ∼ fourfold. Similarly, at 5 h of exposure to hypobaria, total power increased ∼ twofold with a very modest increase in an R-R of ∼ 9%. Increase in spectral power was appreciable even after normalization with mean R-R(2). Increase in VLF during immersion was more than reported during enalaprilat blockade of angiotensin convertase enzyme. Plasma renin activity did not vary during hypobaria. There was a significant increase in pNN50, an established marker of cardiac vagal activity. Centre frequencies of the spectra and slope (β) of the relation between log(PSD) and log(frequency) did not change. Results were supportive of the notion that the parasympathetic system is pre-potent to influence slower (than respiratory) frequency components in HRV spectrum. Additionally, such an effect was without a change in the time constant of effector responses or pacemaker frequencies of VLF and LF periodicities and HRV was not a simple linear surrogate for cardiac vagal effects. An invariance of spectral exponent (β) ruled out

Wavelet transform analysis to assess oscillations in pial artery pulsation at the human cardiac frequency.

PubMed

Winklewski, P J; Gruszecki, M; Wolf, J; Swierblewska, E; Kunicka, K; Wszedybyl-Winklewska, M; Guminski, W; Zabulewicz, J; Frydrychowski, A F; Bieniaszewski, L; Narkiewicz, K

2015-05-01

Pial artery adjustments to changes in blood pressure (BP) may last only seconds in humans. Using a novel method called near-infrared transillumination backscattering sounding (NIR-T/BSS) that allows for the non-invasive measurement of pial artery pulsation (cc-TQ) in humans, we aimed to assess the relationship between spontaneous oscillations in BP and cc-TQ at frequencies between 0.5 Hz and 5 Hz. We hypothesized that analysis of very short data segments would enable the estimation of changes in the cardiac contribution to the BP vs. cc-TQ relationship during very rapid pial artery adjustments to external stimuli. BP and pial artery oscillations during baseline (70s and 10s signals) and the response to maximal breath-hold apnea were studied in eighteen healthy subjects. The cc-TQ was measured using NIR-T/BSS; cerebral blood flow velocity, the pulsatility index and the resistive index were measured using Doppler ultrasound of the left internal carotid artery; heart rate and beat-to-beat systolic and diastolic blood pressure were recorded using a Finometer; end-tidal CO2 was measured using a medical gas analyzer. Wavelet transform analysis was used to assess the relationship between BP and cc-TQ oscillations. The recordings lasting 10s and representing 10 cycles with a frequency of ~1 Hz provided sufficient accuracy with respect to wavelet coherence and wavelet phase coherence values and yielded similar results to those obtained from approximately 70cycles (70s). A slight but significant decrease in wavelet coherence between augmented BP and cc-TQ oscillations was observed by the end of apnea. Wavelet transform analysis can be used to assess the relationship between BP and cc-TQ oscillations at cardiac frequency using signals intervals as short as 10s. Apnea slightly decreases the contribution of cardiac activity to BP and cc-TQ oscillations. Copyright © 2015 Elsevier Inc. All rights reserved.

REPRODUCTIVE AND DEVELOPMENTAL EFFECTS IN MAMMALIAN AND AVIAN SPECIES FROM EXPOSURE TO ELF (EXTREMELY LOW FREQUENCY) FIELDS

EPA Science Inventory

This paper critically reviews the Extremely Low Frequency (ELF) Electromagnetic Fields literature from 1978 to the present in regard to research dealing with the reproductive and developmental effects of exposure.

Oscillations During Thermonuclear X-ray Bursts

NASA Technical Reports Server (NTRS)

Strohmayer, Tod E.; White, Nicholas E. (Technical Monitor)

2001-01-01

High amplitude, nearly coherent X-ray brightness oscillations during thermonuclear X-ray bursts were discovered with the Rossi X-ray Timing Explorer (RXTE) in early 1996. Spectral and timing evidence strongly supports the conclusion that these oscillations are caused by rotational modulation of the burst emission and that they reveal the spin frequency of neutron stars in low mass X-ray binaries, a long sought goal of X-ray astronomy. Studies carried out over the past year have led to the discovery of burst oscillations in four new sources, bringing to ten the number with confirmed burst oscillations. I review the status of our knowledge of these oscillations and indicate how they can be used to probe the physics of neutron stars. For a few burst oscillation sources it has been proposed that the strongest and most ubiquitous frequency is actually the first overtone of the spin frequency and hence that two nearly antipodal hot spots are present on the neutron star. This inference has important implications for both the physics of thermonuclear burning as well as the mass - radius relation for neutron stars, so its confirmation is crucial. I discuss recent attempts to confirm this hypothesis for 4U 1636-53, the source for which a signal at the putative fundamental (290Hz) has, been claimed.

Frequency of gamma oscillations in humans is modulated by velocity of visual motion

PubMed Central

Butorina, Anna V.; Sysoeva, Olga V.; Prokofyev, Andrey O.; Nikolaeva, Anastasia Yu.; Stroganova, Tatiana A.

2015-01-01

Gamma oscillations are generated in networks of inhibitory fast-spiking (FS) parvalbumin-positive (PV) interneurons and pyramidal cells. In animals, gamma frequency is modulated by the velocity of visual motion; the effect of velocity has not been evaluated in humans. In this work, we have studied velocity-related modulations of gamma frequency in children using MEG/EEG. We also investigated whether such modulations predict the prominence of the “spatial suppression” effect (Tadin D, Lappin JS, Gilroy LA, Blake R. Nature 424: 312-315, 2003) that is thought to depend on cortical center-surround inhibitory mechanisms. MEG/EEG was recorded in 27 normal boys aged 8–15 yr while they watched high-contrast black-and-white annular gratings drifting with velocities of 1.2, 3.6, and 6.0°/s and performed a simple detection task. The spatial suppression effect was assessed in a separate psychophysical experiment. MEG gamma oscillation frequency increased while power decreased with increasing velocity of visual motion. In EEG, the effects were less reliable. The frequencies of the velocity-specific gamma peaks were 64.9, 74.8, and 87.1 Hz for the slow, medium, and fast motions, respectively. The frequency of the gamma response elicited during slow and medium velocity of visual motion decreased with subject age, whereas the range of gamma frequency modulation by velocity increased with age. The frequency modulation range predicted spatial suppression even after controlling for the effect of age. We suggest that the modulation of the MEG gamma frequency by velocity of visual motion reflects excitability of cortical inhibitory circuits and can be used to investigate their normal and pathological development in the human brain. PMID:25925324

1645-nm single-frequency, injection-seeded Q-switched Er:YAG master oscillator and power amplifier

NASA Astrophysics Data System (ADS)

Wang, Shuo; Gao, Chunqing; Shi, Yang; Song, Rui; Na, Quanxin; Gao, Mingwei; Wang, Qing

2018-02-01

A 1645-nm injection-seeded Q-switched Er:YAG master oscillator and power amplifier system is reported. The master oscillator generates single-frequency pulse energy of 11.10 mJ with a pulse width of 188.8 ns at 200 Hz. An Er:YAG monolithic nonplanar ring oscillator is employed as a seed laser. The output pulse from the master oscillator is amplified to 14.33-mJ pulse energy through an Er:YAG amplifier, with a pulse width of 183.3 ns. The M2-factors behind the amplifier are 1.14 and 1.23 in x- and y-directions, respectively. The full width at half maximum of the fast Fourier transformation spectrum of the heterodyne beating signal is 2.84 MHz.

The low-frequency encoding disadvantage: Word frequency affects processing demands.

PubMed

Diana, Rachel A; Reder, Lynne M

2006-07-01

Low-frequency words produce more hits and fewer false alarms than high-frequency words in a recognition task. The low-frequency hit rate advantage has sometimes been attributed to processes that operate during the recognition test (e.g., L. M. Reder et al., 2000). When tasks other than recognition, such as recall, cued recall, or associative recognition, are used, the effects seem to contradict a low-frequency advantage in memory. Four experiments are presented to support the claim that in addition to the advantage of low-frequency words at retrieval, there is a low-frequency disadvantage during encoding. That is, low-frequency words require more processing resources to be encoded episodically than high-frequency words. Under encoding conditions in which processing resources are limited, low-frequency words show a larger decrement in recognition than high-frequency words. Also, studying items (pictures and words of varying frequencies) along with low-frequency words reduces performance for those stimuli. Copyright 2006 APA, all rights reserved.

Low-frequency oscillations of the East Asia-Pacific teleconnection pattern and their impacts on persistent heavy precipitation in the Yangtze-Huai River valley

NASA Astrophysics Data System (ADS)

Li, Lei; Zhai, Panmao; Chen, Yang; Ni, Yunqi

2016-06-01

Based on the daily reanalysis data from NCEP-NCAR and daily precipitation data from the China National Meteorological Information Center, an ensemble empirical mode decomposition method is employed to extract the predominant oscillation modes of the East Asia-Pacific (EAP) teleconnection pattern. The influences of these low-frequency modes on persistent heavy precipitation in the Yangtze-Huai River (YHR) valley are investigated. The results indicate that the EAP pattern and rainfall in YHR valley both exhibit remarkable 10-30- and 30-60-day oscillations. The impacts of the EAP pattern on the YHR persistent heavy precipitation can be found on both the 10-30- and 30-60-day timescales—the 10-30-day scale for most cases. Composite analysis indicates that, on the 10-30-day timescale, formation of the EAP pattern in the lower and middle troposphere is determined by convective systems near the tropical western Pacific; whereas in the middle troposphere, the phase transition is jointly contributed by both the dispersion of zonal wave energies at higher latitudes and convective systems over the South China Sea. In the context of the 10-30-day EAP pattern, the anomalously abundant moisture is transported by an anomalous subtropical anticyclone system, and strong moisture convergence results from that anomalous anticyclone system and a cyclonic system in the midlatitude East Asia. Such a combination of systems persists for at least three days, contributing to the formation of persistent heavy precipitation in the YHR valley.

The effects of ion channel blockers validate the conductance-based model of saccadic oscillations

PubMed Central

Shaikh, Aasef G.; Zee, David S.; Optican, Lance M.; Miura, Kenichiro; Ramat, Stefano; Leigh, R. John

2012-01-01

Conductance-based models of reciprocally inhibiting burst neurons suggest that intrinsic membrane properties and postinhibitory rebound (PIR) determine the amplitude and frequency of saccadic oscillations. Reduction of the low-threshold calcium currents (IT) in the model decreased the amplitude but increased the frequency of the simulated oscillations. Combined reduction of hyperpolarization-activated cation current (Ih) and IT in the model abolished the simulated oscillations. We measured the effects of a selective blocker of IT (ethosuximide) in healthy subjects on the amplitude and frequency of saccadic oscillations evoked by eye closure and of a nonselective blocker of Ih and IT (propronolol) in a patient with microsaccadic oscillation and limb tremor syndrome (mSOLT). Ethosuximide significantly reduced the amplitude but increased the frequency of the saccadic oscillations during eye closure in healthy subjects. Propranolol abolished saccadic oscillations in the mSOLT patient. These results support the hypothetical role of postinhibitory rebound, Ih, and IT, in generation of saccadic oscillations and determining their kinematic properties. PMID:21950976

Revealing plasma oscillation in THz spectrum from laser plasma of molecular jet.

PubMed

Li, Na; Bai, Ya; Miao, Tianshi; Liu, Peng; Li, Ruxin; Xu, Zhizhan

2016-10-03

Contribution of plasma oscillation to the broadband terahertz (THz) emission is revealed by interacting two-color (ω/2ω) laser pulses with a supersonic jet of nitrogen molecules. Temporal and spectral shifts of THz waves are observed as the plasma density varies. The former owes to the changing refractive index of the THz waves, and the latter correlates to the varying plasma frequency. Simulation of considering photocurrents, plasma oscillation and decaying plasma density explains the broadband THz spectrum and the varying THz spectrum. Plasma oscillation only contributes to THz waves at low plasma density owing to negligible plasma absorption. At the longer medium or higher density, the combining effects of plasma oscillation and absorption results in the observed low-frequency broadband THz spectra.

Negative feedback system reduces pump oscillations

NASA Technical Reports Server (NTRS)

Rosenmann, W.

1967-01-01

External negative feedback system counteracts low frequency oscillations in rocket engine propellant pumps. The system uses a control piston to sense pump discharge fluid on one side and a gas pocket on the other.

Anatomical and functional assemblies of brain BOLD oscillations

PubMed Central

Baria, Alexis T.; Baliki, Marwan N.; Parrish, Todd; Apkarian, A. Vania

2011-01-01

Brain oscillatory activity has long been thought to have spatial properties, the details of which are unresolved. Here we examine spatial organizational rules for the human brain oscillatory activity as measured by blood oxygen level-dependent (BOLD). Resting state BOLD signal was transformed into frequency space (Welch’s method), averaged across subjects, and its spatial distribution studied as a function of four frequency bands, spanning the full bandwidth of BOLD. The brain showed anatomically constrained distribution of power for each frequency band. This result was replicated on a repository dataset of 195 subjects. Next, we examined larger-scale organization by parceling the neocortex into regions approximating Brodmann Areas (BAs). This indicated that BAs of simple function/connectivity (unimodal), vs. complex properties (transmodal), are dominated by low frequency BOLD oscillations, and within the visual ventral stream we observe a graded shift of power to higher frequency bands for BAs further removed from the primary visual cortex (increased complexity), linking frequency properties of BOLD to hodology. Additionally, BOLD oscillation properties for the default mode network demonstrated that it is composed of distinct frequency dependent regions. When the same analysis was performed on a visual-motor task, frequency-dependent global and voxel-wise shifts in BOLD oscillations could be detected at brain sites mostly outside those identified with general linear modeling. Thus, analysis of BOLD oscillations in full bandwidth uncovers novel brain organizational rules, linking anatomical structures and functional networks to characteristic BOLD oscillations. The approach also identifies changes in brain intrinsic properties in relation to responses to external inputs. PMID:21613505

Low frequency North Atlantic SST variability: Weather noise forcing and coupled response