Sea breeze: Induced mesoscale systems and severe weather

NASA Technical Reports Server (NTRS)

Nicholls, M. E.; Pielke, R. A.; Cotton, W. R.

1990-01-01

Sea-breeze-deep convective interactions over the Florida peninsula were investigated using a cloud/mesoscale numerical model. The objective was to gain a better understanding of sea-breeze and deep convective interactions over the Florida peninsula using a high resolution convectively explicit model and to use these results to evaluate convective parameterization schemes. A 3-D numerical investigation of Florida convection was completed. The Kuo and Fritsch-Chappell parameterization schemes are summarized and evaluated.

Problematizing the Practicum to Integrate Practical Knowledge

ERIC Educational Resources Information Center

Melville, Wayne; Campbell, Todd; Fazio, Xavier; Stefanile, Antonio; Tkaczyk, Nicholas

2014-01-01

This article examines the influence of a practicum teaching experience on two pre-service science teachers. The research is focused on examining a practicum in a secondary science department that actively promotes the teaching and learning of science as inquiry. We investigated the process through which the pre-service science teachers integrated…

Research on Teaching Practicum--A Systematic Review

ERIC Educational Resources Information Center

Lawson, Tony; Çakmak, Melek; Gündüz, Müge; Busher, Hugh

2015-01-01

The aim of the present study is to conduct a systematic review research which focuses on research studies into the school practicum. In order to identify the main issues and also to provide a contemporary picture of practicum, 114 studies published on the topic are reviewed and analysed in terms of: (i) aims, (ii) main participants, (iii)…

Sea breezes and advective effects in southwest James Bay

NASA Technical Reports Server (NTRS)

Mckendry, Ian; Roulet, Nigel

1994-01-01

Observations from a transect extending 100 km inland during the Northern Wetlands Study (NOWES) in 1990 show that the sea breeze develops on approximately 25% of days during summer and may penetrate up to 100 km inland on occasions. The sea breeze exhibits a marked diurnal clockwise rotation as a result of the Coriolis effect along the unobstructed coastline. The marine advective effect is shown to depend on gradient wind direction. With northwesterly upper level flow the sea breeze tends to be northeasterly in direction and is associated with decreased temperatures and vapor pressure deficits (VPD). With southwesterly upper level flow the sea breeze tends to have a southeasterly direction and less effect on temperatures and VPD. This is attributed to shorter residence times of air parcels over water. For two cases, Colorado State University mesoscale model simulations show good agreement with surface wind observations and suggest that under northwesterly gradient flow, Bowen ratios are increased in the onshore flow along western James Bay, while during southwesterly gradient flow these effects are negligible. These results have implications for the interpretation of local climate, ecology, and hydrology as well as land-based and airborne turbulent flux measurements made during NOWES.

Medical informatics education needs information system practicums in health care settings--experiences and lessons learned from 32 practicums at four universities in two countries.

PubMed

Haux, R; Ammenwerth, E; Häber, A; Hübner-Bloder, G; Knaup-Gregori, P; Lechleitner, G; Leiner, F; Weber, R; Winter, A; Wolff, A C

2006-01-01

To report about the themes and about experiences with practicums in the management of information systems in health care settings (health information management) for medical informatics students. We first summarize the topics of the health information management practicums/projects that the authors organized between 1990 and 2003 for the medical informatics programs at Heidelberg/Heilbronn, Germany, UMIT, Austria, as well as for the informatics program at the University of Leipzig, Germany. Experiences and lessons learned, obtained from the faculty that organized the practicums in the past 14 years, are reported. Thirty (of 32) health information management practicums focused on the analysis of health information systems. These took place inside university medical centers. Although the practicums were time-intensive and required intensively tutoring students with regard to health information management and project management, feedback from the students and graduates was mainly positive. It is clearly recommended that students specializing in medical informatics need to be confronted with real-world problems of health information systems during their studies.

Dialogue and Reciprocity in an International Teaching Practicum

ERIC Educational Resources Information Center

Parr, Graham; Faulkner, Julie; Rowe, Craig

2017-01-01

Many teacher education institutions across the world are now initiating and supporting international teaching practicums to better prepare their teaching graduates to teach for diversity. Recently, some of these practicums have embedded service-learning structures and discourses to further encourage pre-service teachers (PSTs) to think beyond…

A case study of sea breeze circulation at Thumba Coast through observations and modelling

NASA Astrophysics Data System (ADS)

Kunhikrishnan, P. K.; Ramachandran, Radhika; Alappattu, Denny P.; Kiran Kumar, N. V. P.; Balasubrahamanyam, D.

2006-12-01

A case study of sea breeze circulation at a coastal region Thumba (8.5°N, 76.9°E) was carried out using Doppler Sodar, surface wind, temperature, humidity measurements and radiosonde ascents. The analysis of surface meteorological data showed that the onset of sea breeze on 12th April 2006 was at 0945 hrs. GPS sonde observation over sea at 1425 hrs and Radiosonde observation over land at 1730 showed a well developed sea breeze circulation over Thumba coast by afternoon hours. The vertical extent of sea breeze circulation was ~1000m over sea as well as on land. The Thermal Internal Boundary Layer (TIBL) depth associated with sea breeze circulation was about 400m at 8 km away from coast. The marine mixed layer height was ~500m about 12 km away from the coast. Numerical simulation of sea breeze was made using HRM (High Resolution Model) and compared the results with the observations.

Land- and sea-surface impacts on local coastal breezes

NASA Astrophysics Data System (ADS)

Veron, D. E.; Hughes, C.; Gilchrist, J.; Lodise, J.; Goldman, W.

2014-12-01

The state of Delaware has seen significant increases in population along the coastline in the past three decades. With this increase in population have come changes to the land surface, as forest and farmland has been converted to residential and commercial purposes, causing changes in the surface roughness, temperature, and land-atmosphere fluxes. There is also a semi-permanent upwelling center in the spring and summer outside the Delaware Bay mouth that significantly changes the structure of the sea surface temperature both inside and outside the Bay. Through a series of high resolution modeling and observational studies, we have determined that in cases of strong synoptic forcing, the impact of the land-surface on the boundary layer properties can be advected offshore, creating a false coastline and modifying the location and timing of the sea breeze circulation. In cases of weak synoptic forcing, the influence of the upwelling and the tidal circulation of the Delaware Bay waters can greatly change the location, strength, and penetration of the sea breeze. Understanding the importance of local variability in the surface-atmosphere interactions on the sea breeze can lead to improved prediction of sea breeze onset, penetration, and duration which is important for monitoring air quality and developing offshore wind power production.

Student Perceptions of Online Practicum: A Case Study

ERIC Educational Resources Information Center

Wilcox, Gabrielle; Lock, Jennifer

2017-01-01

The purpose of the study was to investigate practicum students' perceptions of their experience with an online practicum course in an Applied School Psychology graduate program. With the use of synchronous and asynchronous communication technology, the instructor and students met in the online environment to engage in discussion with regard to…

Preservice Science Teachers Reflect on Their Practicum Experiences

ERIC Educational Resources Information Center

Koc, Isil

2012-01-01

The practicum provides an opportunity for preservice teachers to apply knowledge and skills in actual classroom settings. Thus, it serves as a central component of virtually all teacher education programmes. This study focused the views of 16 preservice science teachers on their practicum experiences. Individual interviews were made to construct a…

Gestalt Therapy and the Counseling Practicum: A Marriage.

ERIC Educational Resources Information Center

Witchel, Robert

This paper briefly summarizes the literature relating to the counseling practicum experience, as well as reviews the development and basic principles of Gestalt therapy. A marriage between the Gestalt therapy approach and the counseling practicum is developed as follows: "Experiential learning, the here-and-now, I-and-thou, and integrating…

Examining Perception of Competency through Practicum Competencies Outline

ERIC Educational Resources Information Center

Esposito, Giovanna; Freda, Maria Francesca; Bosco, Valentina

2015-01-01

Purpose: This study aims to examine the self-perceived competencies of 231 Italian students enrolled in a psychological degree program and involved in a practicum. It analyzes the subjective perception of the competences that students expect to develop, acknowledge as developed and that might be inferred from tasks performed during the practicum;…

Variability of three-dimensional sea breeze structure in southern France: observations and evaluation of empirical scaling laws

NASA Astrophysics Data System (ADS)

Drobinski, P.; Bastin, S.; Dabas, A.; Delville, P.; Reitebuch, O.

2006-08-01

Sea-breeze dynamics in southern France is investigated using an airborne Doppler lidar, a meteorological surface station network and radiosoundings, in the framework of the ESCOMPTE experiment conducted during summer 2001 in order to evaluate the role of thermal circulations on pollutant transport and ventilation. The airborne Doppler lidar WIND contributed to three-dimensional (3-D) mapping of the sea breeze circulation in an unprecedented way. The data allow access to the onshore and offshore sea breeze extents (xsb), and to the sea breeze depth (zsb) and intensity (usb). They also show that the return flow of the sea breeze circulation is very seldom seen in this area due to (i) the presence of a systematic non zero background wind, and (ii) the 3-D structure of the sea breeze caused by the complex coastline shape and topography. A thorough analysis is conducted on the impact of the two main valleys (Rhône and Durance valleys) affecting the sea breeze circulation in the area.

Finally, this dataset also allows an evaluation of the existing scaling laws used to derive the sea breeze intensity, depth and horizontal extent. The main results of this study are that (i) latitude, cumulative heating and surface friction are key parameters of the sea breeze dynamics; (ii) in presence of strong synoptic flow, all scaling laws fail in predicting the sea breeze characteristics (the sea breeze depth, however being the most accurately predicted); and (iii) the ratio zsb/usb is approximately constant in the sea breeze flow.

Early Practicum Experiences: Preservice Early Childhood Students' Perceptions and Sense of Efficacy

ERIC Educational Resources Information Center

Van Schagen Johnson, Amy; La Paro, Karen M.; Crosby, Danielle A.

2017-01-01

The current study explored early practicum experiences (those occurring before student teaching) in an early childhood birth to kindergarten teacher education program. Undergraduates enrolled in practicum courses completed questionnaires about their overall practicum experience including: socio-emotional components (their perceived fit with their…

Benefits and Challenges of Supervising an International Practicum

ERIC Educational Resources Information Center

Gilliland, Betsy

2015-01-01

In this reflective essay, I share my experiences as a US-based professor leading graduate students on a 2-month teaching practicum in northern Thailand. I describe the process of arranging the practicum in coordination with the host university and the challenges of teaching 2 teacher-education courses while also mentoring novice teachers and…

The Clinical/Practicum Experience in Professional Preparation: Preliminary Findings

ERIC Educational Resources Information Center

Ralph, Edwin George; Walker, Keith; Wimmer, Randy

2008-01-01

The authors synthesize preliminary findings from an interdisciplinary study of the practicum/clinical phase of undergraduate pre-service education in the professions. Early data analysis identified similarities and differences across disciplines in terms of: (a) the terminology describing each practicum program, (b) the programs' key…

Practicum Assessment of Culturally and Linguistically Diverse Early Childhood Pre-Service Teachers

ERIC Educational Resources Information Center

Nuttall, Joce; Ortlipp, Michelle

2012-01-01

The practicum is an integral component of teacher education courses, but culturally and linguistically diverse pre-service teachers can face particular struggles in meeting assessment requirements on the practicum in early childhood settings. This paper reports from a small, exploratory study of early childhood practicum handbooks from four…

Practicum Teachers' Perceptions of Success in Relation to Self-Efficacy (Perceived Competence)

ERIC Educational Resources Information Center

Anderson, Kirk; Walker, Keith; Ralph, Edwin

2009-01-01

How do student teachers gain confidence in their teaching abilities as part of their school-based practicum experience while increasing their self-efficacy from the successes of their practicum? To understand this question better, we explored preservice teachers' post-practicum accounts of experiences of success in relation to efficacy (Bandura,…

Investigation on the fine structure of sea-breeze during ESCOMPTE experiment

NASA Astrophysics Data System (ADS)

Puygrenier, V.; Lohou, F.; Campistron, B.; Saïd, F.; Pigeon, G.; Bénech, B.; Serça, D.

2005-03-01

Surface and remote-sensing instruments deployed during ESCOMPTE experiment over the Marseille area, along the Mediterranean coast, were used to investigate the fine structure of the atmospheric boundary layer (ABL) during sea-breeze circulation in relation to pollutant transport and diffusion. Six sea-breeze events are analyzed with a particular focus on 25 June 2001. Advection of cool and humid marine air over land has a profound influence on the daytime ABL characteristics. This impact decreases rapidly with the inland distance from the sea. Nearby the coast (3 km inland), the mixing height Zi rises up to 750 m and falls down after 15:00 (UT) when the breeze flow reaches its maximum intensity. A more classical evolution of the ABL is observed at only 11-km inland where Zi culminates in the morning and stabilizes in the afternoon at about 1000 m height. Fine inspection of the data revealed an oscillation of the sea-breeze with a period about 2 h 47 min. This feature, clearly discernable for 3 days at least, is present in several atmospheric variables such as wind, temperature, not only at the ground but also aloft in the ABL as observed by sodar/RASS and UHF wind profilers. In particular, the mixing height Zi deduced from UHF profilers observations is affected also by the same periodicity. This pulsated sea-breeze is observed principally above Marseille and, at the northern and eastern shores of the Berre pond. In summary, the periodic intrusion over land of cool marine air modifies the structure of the ABL in the vicinity of the coast from the point of view of stability, turbulent motions and pollutants concentration. An explanation of the source of this pulsated sea-breeze is suggested.

North-western Mediterranean sea-breeze circulation in a regional climate system model

NASA Astrophysics Data System (ADS)

Drobinski, Philippe; Bastin, Sophie; Arsouze, Thomas; Béranger, Karine; Flaounas, Emmanouil; Stéfanon, Marc

2017-04-01

In the Mediterranean basin, moisture transport can occur over large distance from remote regions by the synoptic circulation or more locally by sea breezes, driven by land-sea thermal contrast. Sea breezes play an important role in inland transport of moisture especially between late spring and early fall. In order to explicitly represent the two-way interactions at the atmosphere-ocean interface in the Mediterranean region and quantify the role of air-sea feedbacks on regional meteorology and climate, simulations at 20 km resolution performed with WRF regional climate model (RCM) and MORCE atmosphere-ocean regional climate model (AORCM) coupling WRF and NEMO-MED12 in the frame of HyMeX/MED-CORDEX are compared. One result of this study is that these simulations reproduce remarkably well the intensity, direction and inland penetration of the sea breeze and even the existence of the shallow sea breeze despite the overestimate of temperature over land in both simulations. The coupled simulation provides a more realistic representation of the evolution of the SST field at fine scale than the atmosphere-only one. Temperature and moisture anomalies are created in direct response to the SST anomaly and are advected by the sea breeze over land. However, the SST anomalies are not of sufficient magnitude to affect the large-scale sea-breeze circulation. The temperature anomalies are quickly damped by strong surface heating over land, whereas the water vapor mixing ratio anomalies are transported further inland. The inland limit of significance is imposed by the vertical dilution in a deeper continental boundary-layer.

Idealized WRF model sensitivity simulations of sea breeze types and their effects on offshore windfields

NASA Astrophysics Data System (ADS)

Steele, C. J.; Dorling, S. R.; von Glasow, R.; Bacon, J.

2012-06-01

The behaviour and characteristics of the marine component of sea breeze cells have received little attention relative to their onshore counterparts. Yet there is a growing interest and dependence on the offshore wind climate from, for example, a wind energy perspective. Using idealized model experiments, we investigate the sea breeze circulation at scales which approximate to those of the Southern North Sea, a region of major ongoing offshore wind farm development. We also contrast the scales and characteristics of the pure and the little known corkscrew and backdoor sea breeze types, where the type is pre-defined by the orientation of the synoptic scale flow relative to the shoreline. We find, crucially, that pure sea breezes, in contrast to corkscrew and backdoor types, can lead to substantial wind speed reductions offshore and that the addition of a second eastern coastline emphasises this effect through generation of offshore "calm zones". The offshore extent of all sea breeze types is found to be sensitive to both the influence of Coriolis acceleration and to the boundary layer scheme selected. These extents range, for example for a pure sea breeze produced in a 2 m s-1 offshore gradient wind, from 10 km to 40 km between the Mellor-Yamada-Nakanishi-Niino and the Yonsei State University schemes, respectively. The corkscrew type restricts the development of a backdoor sea breeze on the eastern coast and is also capable of traversing a 100 km offshore domain even under high gradient wind speed (>15 m s-1) conditions. Realistic variations in sea surface skin temperature during the sea breeze season do not significantly affect the circulation, suggesting that a thermal contrast is only needed as a precondition to the development of the sea breeze. We highlight how sea breeze impacts on circulation need to be considered in order to improve the accuracy of assessments of the offshore wind energy climate.

Meteorological and Land Surface Properties Impacting Sea Breeze Extent and Aerosol Distribution in a Dry Environment

NASA Astrophysics Data System (ADS)

Igel, Adele L.; van den Heever, Susan C.; Johnson, Jill S.

2018-01-01

The properties of sea breeze circulations are influenced by a variety of meteorological and geophysical factors that interact with one another. These circulations can redistribute aerosol particles and pollution and therefore can play an important role in local air quality, as well as impact remote sensing. In this study, we select 11 factors that have the potential to impact either the sea breeze circulation properties and/or the spatial distribution of aerosols. Simulations are run to identify which of the 11 factors have the largest influence on the sea breeze properties and aerosol concentrations and to subsequently understand the mean response of these variables to the selected factors. All simulations are designed to be representative of conditions in coastal sub tropical environments and are thus relatively dry, as such they do not support deep convection associated with the sea breeze front. For this dry sea breeze regime, we find that the background wind speed was the most influential factor for the sea breeze propagation, with the soil saturation fraction also being important. For the spatial aerosol distribution, the most important factors were the soil moisture, sea-air temperature difference, and the initial boundary layer height. The importance of these factors seems to be strongly tied to the development of the surface-based mixed layer both ahead of and behind the sea breeze front. This study highlights potential avenues for further research regarding sea breeze dynamics and the impact of sea breeze circulations on pollution dispersion and remote sensing algorithms.

Bay Breeze Influence on Surface Ozone at Edgewood, MD During July 2011

NASA Technical Reports Server (NTRS)

Stauffer, Ryan M.; Thompson, Anne M.; Martins, Douglas K.; Clark, Richard D.; Goldberg, Daniel L.; Loughner, Christopher P.; Delgado, Ruben; Dickerson, Russell R.; Stehr, Jeffrey W.; Tzortziou, Maria A.

2012-01-01

Surface ozone (O3) was analyzed to investigate the role of the bay breeze on air quality at two locations in Edgewood, Maryland (lat: 39.4deg, lon: -76.3deg) for the month of July 2011. Measurements were taken as part of the first year of NASA's "Deriving Information on Surface Conditions from Column and Vertically Resolved Observations Relevant to Air Quality" (DISCOVER-AQ) Earth Venture campaign and as part of NASA's Geostationary for Coastal and Air Pollution Events Chesapeake Bay Oceanographic campaign with DISCOVER-AQ (Geo-CAPE CBODAQ). Geo-CAPE CBODAQ complements DISCOVER-AQ by providing ship-based observations over the Chesapeake Bay. A major goal of DISCOVER-AQ is determining the relative roles of sources, photochemistry and local meteorology during air quality events in the Mid-Atlantic region of the U.S. Surface characteristics, transport and vertical structures of O3 during bay breezes were identified using in-situ surface, balloon and aircraft data, along with remote sensing equipment. Localized late day peaks in O3 were observed during bay breeze days, maximizing an average of 3 h later compared to days without bay breezes. Of the 10 days of July 2011 that violated the U.S. Environmental Protection Agency (EPA) 8 h O3 standard of 75 parts per billion by volume (ppbv) at Edgewood, eight exhibited evidence of a bay breeze circulation. The results indicate that while bay breezes and the processes associated with them are not necessary to cause exceedances in this area, bay breezes exacerbate poor air quality that sustains into the late evening hours at Edgewood. The vertical and horizontal distributions of O3 from the coastal Edgewood area to the bay also show large gradients that are often determined by boundary layer stability. Thus, developing air quality models that can sufficiently resolve these dynamics and associated chemistry, along with more consistent monitoring of O3 and meteorology on and along the complex coastline of Chesapeake Bay must be a

Bay breeze influence on surface ozone at Edgewood, MD during July 2011.

PubMed

Stauffer, Ryan M; Thompson, Anne M; Martins, Douglas K; Clark, Richard D; Goldberg, Daniel L; Loughner, Christopher P; Delgado, Ruben; Dickerson, Russell R; Stehr, Jeffrey W; Tzortziou, Maria A

Surface ozone (O 3 ) was analyzed to investigate the role of the bay breeze on air quality at two locations in Edgewood, Maryland (lat: 39.4°, lon: -76.3°) for the month of July 2011. Measurements were taken as part of the first year of NASA's "Deriving Information on Surface Conditions from Column and Vertically Resolved Observations Relevant to Air Quality" (DISCOVER-AQ) Earth Venture campaign and as part of NASA's Geostationary for Coastal and Air Pollution Events Chesapeake Bay Oceanographic campaign with DISCOVER-AQ (Geo-CAPE CBODAQ). Geo-CAPE CBODAQ complements DISCOVER-AQ by providing ship-based observations over the Chesapeake Bay. A major goal of DISCOVER-AQ is determining the relative roles of sources, photochemistry and local meteorology during air quality events in the Mid-Atlantic region of the U.S. Surface characteristics, transport and vertical structures of O 3 during bay breezes were identified using in-situ surface, balloon and aircraft data, along with remote sensing equipment. Localized late day peaks in O 3 were observed during bay breeze days, maximizing an average of 3 h later compared to days without bay breezes. Of the 10 days of July 2011 that violated the U.S. Environmental Protection Agency (EPA) 8 h O 3 standard of 75 parts per billion by volume (ppbv) at Edgewood, eight exhibited evidence of a bay breeze circulation. The results indicate that while bay breezes and the processes associated with them are not necessary to cause exceedances in this area, bay breezes exacerbate poor air quality that sustains into the late evening hours at Edgewood. The vertical and horizontal distributions of O 3 from the coastal Edgewood area to the bay also show large gradients that are often determined by boundary layer stability. Thus, developing air quality models that can sufficiently resolve these dynamics and associated chemistry, along with more consistent monitoring of O 3 and meteorology on and along the complex coastline of Chesapeake Bay

Sensitivity of Offshore Surface Fluxes and Sea Breezes to the Spatial Distribution of Sea-Surface Temperature

NASA Astrophysics Data System (ADS)

Lombardo, Kelly; Sinsky, Eric; Edson, James; Whitney, Michael M.; Jia, Yan

2018-03-01

A series of numerical sensitivity experiments is performed to quantify the impact of sea-surface temperature (SST) distribution on offshore surface fluxes and simulated sea-breeze dynamics. The SST simulations of two mid-latitude sea-breeze events over coastal New England are performed using a spatially-uniform SST, as well as spatially-varying SST datasets of 32- and 1-km horizontal resolutions. Offshore surface heat and buoyancy fluxes vary in response to the SST distribution. Local sea-breeze circulations are relatively insensitive, with minimal differences in vertical structure and propagation speed among the experiments. The largest thermal perturbations are confined to the lowest 10% of the sea-breeze column due to the relatively high stability of the mid-Atlantic marine atmospheric boundary layer (ABL) suppressing vertical mixing, resulting in the depth of the marine layer remaining unchanged. Minimal impacts on the column-averaged virtual potential temperature and sea-breeze depth translates to small changes in sea-breeze propagation speed. This indicates that the use of datasets with a fine-scale SST may not produce more accurate sea-breeze simulations in highly stable marine ABL regimes, though may prove more beneficial in less stable sub-tropical environments.

The inland boundary layer at low latitudes: II Sea-breeze influences

NASA Astrophysics Data System (ADS)

Garratt, J. R.; Physick, W. L.

1985-11-01

Two-dimensional mesoscale model results support the claim of evening sea-breeze activity at Daly Waters, 280 km inland from the coast in northern Australia, the site of the Koorin boundary-layer experiment. The sea breeze occurs in conditions of strong onshore and alongshore geostrophic winds, not normally associated with such activity. It manifests itself at Daly Waters and in the model as a cooling in a layer 500 1000 m deep, as an associated surface pressure jump, as strong backing of the wind and, when an offshore low-level wind is present, as a collapse in the inland nocturnal jet. Both observational analysis and model results illustrate the rotational aspects of the deeply penetrating sea breeze; in our analysis this is represented in terms of a surge vector — the vector difference between the post- and pre-frontal low-level winds. There is further evidence to support earlier work that the sea breeze during the afternoon and well into the night — at least for these low-latitude experiments — behaves in many ways as an atmospheric gravity current, and that inland penetrations up to 500 km occur.

An innovative clinical practicum to teach evidence-based practice.

PubMed

Brancato, Vera C

2006-01-01

A clinical practicum was successfully implemented for RN to BSN students to apply evidence-based practice to actual clinical problems affecting nursing practice. The author describes how this practicum was implemented and the requisite resources and support systems. This senior-level capstone course enabled students to understand and value a lifelong learning approach to evidence-based practice.

Idealized WRF model sensitivity simulations of sea breeze types and their effects on offshore windfields

NASA Astrophysics Data System (ADS)

Steele, C. J.; Dorling, S. R.; von Glasow, R.; Bacon, J.

2013-01-01

The behaviour and characteristics of the marine component of sea breeze cells have received little attention relative to their onshore counterparts. Yet there is a growing interest and dependence on the offshore wind climate from, for example, a wind energy perspective. Using idealized model experiments, we investigate the sea breeze circulation at scales which approximate to those of the southern North Sea, a region of major ongoing offshore wind farm development. We also contrast the scales and characteristics of the pure and the little known corkscrew and backdoor sea breeze types, where the type is pre-defined by the orientation of the synoptic scale flow relative to the shoreline. We find, crucially, that pure sea breezes, in contrast to corkscrew and backdoor types, can lead to substantial wind speed reductions offshore and that the addition of a second eastern coastline emphasises this effect through generation of offshore "calm zones". The offshore extent of all sea breeze types is found to be sensitive to both the influence of Coriolis acceleration and to the boundary layer scheme selected. These extents range, for example for a pure sea breeze produced in a 2 m s-1 offshore gradient wind, from 0 km to 21 km between the Mellor-Yamada-Nakanishi-Niino and the Yonsei State University schemes respectively. The corkscrew type restricts the development of a backdoor sea breeze on the opposite coast and is also capable of traversing a 100 km offshore domain even under high along-shore gradient wind speed (>15 m s-1) conditions. Realistic variations in sea surface skin temperature and initializing vertical thermodynamic profile do not significantly alter the resulting circulation, though the strengths of the simulated sea breezes are modulated if the effective land-sea thermal contrast is altered. We highlight how sea breeze impacts on circulation need to be considered in order to improve the accuracy of both assessments of the offshore wind energy climate and

Impact of the Rhône and Durance valleys on sea-breeze circulation in the Marseille area

NASA Astrophysics Data System (ADS)

Bastin, Sophie; Drobinski, Philippe; Dabas, Alain; Delville, Patricia; Reitebuch, Oliver; Werner, Christian

2005-03-01

Sea-breeze dynamics in the Marseille area, in the south of France, is investigated in the framework of the ESCOMPTE experiment conducted during summer 2001 in order to evaluate the role of thermal circulations on pollutant transport and ventilation. Under particular attention in this paper is the sea-breeze channelling by the broad Rhône valley and the narrow Durance valley, both oriented nearly-north-south, i.e., perpendicular to the coastline, and its possible impact on the sea-breeze penetration, intensity and depth, which are key information for air pollution issues. One situation of slight synoptic pressure gradient leading to a northerly flow in the Rhône valley (25 June 2001) and one situation of a weak onshore prevailing synoptic wind (26 June 2001) are compared. The impact of the Rhône and Durance valleys on the sea-breeze dynamics on these two typical days is generalized to the whole ESCOMPTE observing period. The present study shows by combining simple scaling analysis with wind data from meteorological surface stations and Doppler lidars that (i) the Durance valley always affects the sea breeze by accelerating the flow. A consequence is that the Durance valley contributes to weaken the temperature gradient along the valley and thus the sea-breeze circulation. In some cases, the acceleration of the channelled flow in the Durance valley suppresses the sea-breeze flow by temperature gradient inhibition; (ii) the Rhône valley does not generally affect the sea breeze significantly. However, if the sea breeze is combined with an onshore flow, it leads to further penetration inland and intensification of the low-level southerly flow. In this situation, lateral constriction may accelerate the sea breeze. Simple scaling analysis suggests that Saint Paul (44.35°N, about 100 km from the coastline) is the lower limit where sea breeze can be affected by the Rhône valley. These conclusions have implications in air quality topics as channelled sea breeze may

Burning out during the Practicum: The Case of Teacher Trainees

ERIC Educational Resources Information Center

Kokkinos, Constantinos M.; Stavropoulos, George

2016-01-01

The purpose of the present study was to empirically examine the link between practicum-related stressors, perceived general practicum stress, personal variables (i.e. general and teaching self-efficacy, epistemological beliefs, conceptions about teaching and learning, and trait anxiety) and burnout dimensions in a sample of 174 Greek student…

Examining the Practicum Experience to Increase Counseling Students' Self-Efficacy

ERIC Educational Resources Information Center

Ikonomopoulos, James; Vela, Javier Cavazos; Smith, Wayne D.; Dell'Aquila, Julia

2016-01-01

Counseling graduate students may begin practicum with low self-efficacy regarding their counseling abilities and skills. In the current study, we implemented a small-series (N = 11) single-case research design to assess the effectiveness of the practicum experience to increase counseling students' self-efficacy. Analysis of participants' scores on…

Conducting Action Research in a Practicum: A Student Teacher's Perspective

ERIC Educational Resources Information Center

Kasula, Alex

2015-01-01

This article looks at my reflection as a teacher during a master's degree practicum for a Second Language Studies Program. This particular practicum differs from the other common student teacher-training courses found in master's programs as it incorporated a teacher-training session on conducting action research (AR) in the classroom, a practice…

Undergraduate student nurses' lived experiences of anxiety during their first clinical practicum: A phenomenological study.

PubMed

Sun, Fan-Ko; Long, Ann; Tseng, Yun Shan; Huang, Hui-Man; You, Jia-Hui; Chiang, Chun-Ying

2016-02-01

The Fundamental Nursing clinical practicum is an essential module for nursing students. Some feel stress or anxiety about attending this first placement; however, evidence demonstrates that it is rare to explore the feelings of anxiety felt by the nursing students concerning their first clinical practicum. This study was designed to explore student nurses' experiences of anxiety felt regarding their initial clinical practicum while studying for their University degree. A phenomenological approach was used. A university in Southern Taiwan. A purposive sampling of fifteen student nurses with anxiety reactions who had completed their first clinical practicum. Data were collected using a semi-structured guide and deep interview. Data were analyzed using Colaizzi's seven-step phenomenological method. Three themes surfaced in the findings. The first theme was anxiety around their first clinical practicum, which stirred up anxiety about: self-doubt, worry and fear; difficulty coping with the learning process; worry hampered establishing therapeutic relationships with patients; the progress of the patients' illness could not be predicted; and anxiety felt about lecturer-student interactions. The second theme was three phases of anxiety reactions, which included increasing anxiety before clinical practicum; exacerbated anxiety during clinical practicum, and relief of anxiety after clinical practicum. The third theme was coping behaviors. This comprised: self-reflection in preparation for clinical practicum; finding ways to release emotions; distractions from the anxiety; and, also facing their difficulties head-on. The findings could help raise the awareness of lecturers and students by understanding student nurses' anxiety experiences and facilitating a healthy preparation for their initial clinical practicum, consequently proactively helping reduce potential anxiety experiences. Copyright © 2015 Elsevier Ltd. All rights reserved.

Bay breeze climatology at two sites along the Chesapeake bay from 1986-2010: Implications for surface ozone.

PubMed

Stauffer, Ryan M; Thompson, Anne M

Hourly surface meteorological measurements were coupled with surface ozone (O 3 ) mixing ratio measurements at Hampton, Virginia and Baltimore, Maryland, two sites along the Chesapeake Bay in the Mid-Atlantic United States, to examine the behavior of surface O 3 during bay breeze events and quantify the impact of the bay breeze on local O 3 pollution. Analyses were performed for the months of May through September for the years 1986 to 2010. The years were split into three groups to account for increasingly stringent environmental regulations that reduced regional emissions of nitrogen oxides (NO x ): 1986-1994, 1995-2002, and 2003-2010. Each day in the 25-year record was marked either as a bay breeze day, a non-bay breeze day, or a rainy/cloudy day based on the meteorological data. Mean eight hour (8-h) averaged surface O 3 values during bay breeze events were 3 to 5 parts per billion by volume (ppbv) higher at Hampton and Baltimore than on non-bay breeze days in all year periods. Anomalies from mean surface O 3 were highest in the afternoon at both sites during bay breeze days in the 2003-2010 study period. In conjunction with an overall lowering of baseline O 3 after the 1995-2002 period, the percentage of total exceedances of the Environmental Protection Agency (EPA) 75 ppbv 8-h O 3 standard that occurred on bay breeze days increased at Hampton for 2003-2010, while remaining steady at Baltimore. These results suggest that bay breeze circulations are becoming more important to causing exceedance events at particular sites in the region, and support the hypothesis of Martins et al. (2012) that highly localized meteorology increasingly drives air quality events at Hampton.

Great Expectations: The TESOL Practicum as a Professional Learning Experience

ERIC Educational Resources Information Center

Canh, Le Van

2014-01-01

The practicum as a learning opportunity for prospective teachers of ESL or EFL remains underexplored. Most of the studies that have been documented in the TESOL practicum literature were conducted in either North America or a few Asian contexts with novice teachers. In this study the author used diaries by five Vietnamese EFL student teachers as…

Piloting Teacher Education Practicum Partnerships: Teaching Alliances for Professional Practice (TAPP)

ERIC Educational Resources Information Center

Kertesz, John Leslie; Downing, Jill

2016-01-01

This paper reports on a practicum partnerships pilot project between local schools and a teacher preparation program in a medium sized regional university. Whilst addressing recent governmental recommendations for improvements in the teacher education practicum, the project also sought greater suitability by connecting the professional skills of…

Modelling Local Sea-Breeze Flow and Associated Dispersion Patterns Over a Coastal Area in North-East Spain: A Case Study

NASA Astrophysics Data System (ADS)

Soler, M. R.; Arasa, R.; Merino, M.; Olid, M.; Ortega, S.

2011-07-01

The structure and evolution of the sea breeze in the north-west part of the Mediterranean (Catalonia, north-east Spain) is studied both experimentally and, predominantly, using numerical models to increase understanding of sea-breeze structure and three-dimensional (3D) pollution distributions in coastal environments. Sea-breeze components are modelled and analyzed using the fifth-generation Pennsylvania State University-National Centre for Atmospheric Research Mesoscale Model (MM5). The results show that the growth and structure of the sea-breeze circulation is modulated by the synoptic flow and especially by the complex topography of the area. 3D pollution transport in a sea breeze is modelled by coupling the MM5 to the Community Multiscale Air Quality (CMAQ) model, with results indicating that topography and synoptic flow are the main factors modulating horizontal and vertical pollutant transport in sea-breeze episodes. In this way, horizontal dispersion is limited by the complex topography of the area, whilst the sea-breeze flow is intensified by anabatic upslope winds that contribute to vertical pollutant transport. The numerical model results also indicate that the sea-breeze circulation with a weak return flow at upper levels grows due to a synoptic onshore wind component. However, such a sea-breeze circulation is capable of transporting pollutants towards the coast.

The effectiveness of separating theory and practicum as a conduit to learning physiology.

PubMed

Schuijers, Johannes A; McDonald, Stuart J; Julien, Brianna L; Lexis, Louise A; Thomas, Colleen J; Chan, Siew; Samiric, T

2013-06-01

Many conventional science courses contain subjects embedded with laboratory-based activities. However, research on the benefits of positioning the practicals within the theory subject or developing them distinctly from the theory is largely absent. This report compared results in a physiology theory subject among three different cohorts of students: those taking the theory subject alone, those taking it concurrent with a physiology practicum subject, and those who previously took the subject when it had practicums embedded within the one subject. The path model shows that students taking both physiology theory and physiology practicum attained a significantly higher result in online tests compared with those who took the theory subject alone (P < 0.05) and that this translated to a significantly higher result in the end-of-semester examination. Similarly, students taking both physiology theory and the physiology practicum attained a significantly higher end-examination result compared with those who took the physiology subject in previous years when the practicums were embedded within the theory subject (P < 0.05). In both cases, this increase was largely attained in components that tested critical thinking and deep learning (short theory application questions and extended written questions). We conclude that students undertaking both physiology theory and the physiology practicum likely performed better in the theory subject due to better problem-solving skills and a more developed understanding of theoretical content. We suggest that consideration be given in all science curricula to the separation of theory and practicum by developing two subjects with clearly defined different learning outcomes.

Integrating Theory and Practice in the Pre-Service Teacher Education Practicum

ERIC Educational Resources Information Center

Allen, Jeanne Maree; Wright, Suzie Elizabeth

2014-01-01

This article reports on a study into student teachers' perceptions about their professional development during practicum. Framed within a symbolic interactionist perspective, the study examined to what extent, and how effectively, one group of student teachers was able to integrate theory and practice during a three-week practicum in the first…

Applying Kolb's Model to a Nontraditional Preservice Teaching Practicum

ERIC Educational Resources Information Center

Burns, Amy; Danyluk, Patricia

2017-01-01

This article reports on the initial findings of an ongoing study that will see six preservice teachers placed in a nontraditional practicum placement as part of their bachelor of education program. Reported here is the examination of emergent professionalism of the initial two preservice teachers during their nontraditional practicum placement on…

Quality improvement on chemistry practicum courses through implementation of 5E learning cycle

NASA Astrophysics Data System (ADS)

Merdekawati, Krisna

2017-03-01

Two of bachelor of chemical education's competences are having practical skills and mastering chemistry material. Practicum courses are organized to support the competency achievement. Based on observation and evaluation, many problems were found in the implementation of practicum courses. Preliminary study indicated that 5E Learning Cycle can be used as an alternative solution in order to improve the quality of chemistry practicum course. The 5E Learning Cycle can provide positive influence on the achievement of the competence, laboratory skills, and students' understanding. The aim of the research was to describe the feasibility of implementation of 5E Learning Cycle on chemistry practicum courses. The research was based on phenomenology method in qualitative approach. The participants of the research were 5 person of chemistry laboratory manager (lecturers at chemistry and chemistry education department). They concluded that the 5E Learning Cycle could be implemented to improve the quality of the chemistry practicum courses. Practicum guides and assistant competences were organized to support the implementation of 5E Learning Cycle. It needed training for assistants to understand and implement in the stages of 5E Learning Cycle. Preparation of practical guidelines referred to the stages of 5E Learning Cycle, started with the introduction of contextual and applicable materials, then followed with work procedures that accommodate the stage of engagement, exploration, explanation, extension, and evaluation

A characterisation of sea-breeze events in the eastern Cantabrian coast (Spain) from observational data and WRF simulations

NASA Astrophysics Data System (ADS)

Arrillaga, Jon A.; Yagüe, Carlos; Sastre, Mariano; Román-Cascón, Carlos

2016-11-01

The behaviour of the sea breeze along the north coast of Spain is investigated using observations of two topographically contrasting sites together with simulations from the Weather Research and Forecasting (WRF) model. An objective and systematic selection method is used to detect sea-breeze days from a database of two summer months. The direction and intensity of the sea breeze are significantly affected by the topography of the area; indeed, the estimated sea-breeze intensity shows an opposite relationship with the cross-shore temperature gradient for both sites. WRF simulations reproduce the onset of the sea breeze, but some characteristics are not adequately simulated: they generally overestimate the wind speed, smooth the temperature evolution and they do not represent the correct interaction with the terrain-induced flows. Additionally, four sensitivity experiments are performed with the WRF model varying the Planetary Boundary Layer (PBL) scheme, as well as the grid analysis nudging for an anomalous case study which is incorrectly filtered. As the two simulations considering nudging reproduce an unreal (not observed) sea breeze, this day turns out to be of great interest: it allows to evaluate the influence of the passage of the sea-breeze front (SBF) in other variables mainly related to turbulence. Furthermore, the best model scores are obtained for the PBL scheme that does not use a TKE closure.

The Sea Breeze in South-Iceland: Observations with an unmanned aircraft and numerical simulations

NASA Astrophysics Data System (ADS)

Opsanger Jonassen, Marius; Ólafsson, Haraldur; Rasol, Dubravka; Reuder, Joachim

2010-05-01

Sea breeze events, 19-20 July 2009, observed during the international field campaign MOSO, at the southcoast of Iceland, have been investigated using high resolution numerical simulations. Thanks to the use of a small unmanned aircraft system (UAS), SUMO, the wind and temperature aloft could be observed at a high resolution in both space and time. Simultaneously with the UAS operations, conventional platforms were used to obtain surface measurements. The observations show a distinct sea breeze circulation with an onset at around noon and a final decay around 19:00 UTC. At the maximum, the sea breeze layer reached a height of appr. 400 m, marked by a capping wind minimum. When compared to the flow aloft, the sea breeze layer was found to exhibit relatively low temperatures and an expected turn from an off-shore to an on-shore flow. Overall, the agreement between the observations and simulations are relatively good. The simulations suggest a horizontal extent of the circulation some 20-30 km off-shore, but only around 5 km on-shore.

A breeze-driven current on sloped littoral waters

NASA Astrophysics Data System (ADS)

Tohidi, A.; Jamali, M.

2017-12-01

Various natural phenomena, e. g. uniform/non-uniform solar radiation and diurnal cycles, affect water circulation patterns through aquatic canopies, that is (usually shallow) shorelines of the rivers, lakes, and lagoons. Amongst these factors is vegetation that, plays a crucial role in conserving and dispersing the nutrients, oxygen, temperature, and generally regulating the life and interactions of organisms with each other (ecology) in aquatic canopies. So far, however, very little attention has been paid to the effects of very low, breeze-like, winds over the water surface in these vegetated regions. In this exploratory study, the evolution of a breeze-driven gravity current traveling up the slope towards the shorelines is shown, experimentally. The flow is characterized using Particle Image Velocimetry (PIV) technique. In addition, a detailed dimensional analysis of the parameter space of the phenomenon is conducted. The results strongly corroborate the experimental observations.

Psychiatric Psychopathology: A Practicum Approach.

ERIC Educational Resources Information Center

Keller, John W.; Piotrowski, Chris

This paper describes the University of West Florida graduate level, didactic/experiential course in psychopathology which has been offered since 1975 to introduce clinical psychology students to the applied and practical aspects of psychiatry. Elements of the basic practicum course are described: (1) each student is assigned to a psychiatrist on a…

Fog water collection under sea breeze conditions in the Western Mediterranean basin (Valencia region, Spain)

NASA Astrophysics Data System (ADS)

Azorin-Molina, C.; Corell, D.; Estrela, M. J.; Valiente, J. A.

2010-07-01

Orographic fog occurrences associated with sea breezes determine water collection potential over the mountain ranges near the Mediterranean coast of the Iberian Peninsula. Previous works have confirmed that the effect of sea breezes on cloud genera is to increase the frequency of low (Stratus) and convective (Cumulus) clouds. The primary impact of sea breeze flows corresponds to low stratiform clouds (Stratus, St, and Stratocumulus, Sc) formed in the convective internal boundary layer due to the inflow of moist sea air at lower levels. The formation of Sc clouds is caused by the rising and cooling of turbulent moist sea air over the highest slopes of the mountains at the end of the day. In the most Sc formation, we also observed dense fog banks of Stratus nebulosus (St neb) and dew during the early next morning, covering the inland topographical depressions. The aim of this study is to statistically analyze the impact of sea breezes on fog water collection in the convective internal boundary layer. The study area is located in the eastern of the Iberian Peninsula (Valencia region, Spain) and the survey corresponds to a 7-yr study period (2003-2009). This research is based upon a small network of eight passive fog water collectors distributed over 6 coastal- and 2 inland-mountain areas. A cylindrical fog water instrument (i.e. omnidirectional collection efficiency) based on the ASRC (Atmospheric Science Research Centre, State University of New York) string collector is used to sample fog water volumes on a daily basis. These stations also sampled temperature, humidity, wind speed and direction and precipitation measurements. The current study used these meteorological measurements to apply an automated and manual selection methodologies for identifying past sea breeze episodes. The dataset created by means of these selection techniques allows for the study of fog water volumes associated with sea breeze situations. A detailed statistical characterization of the

Raising the Curtain: Investigating the Practicum Experiences of Pre-Service Drama Teachers

ERIC Educational Resources Information Center

Gray, Christina C.; Wright, Peter R.; Pascoe, Robin

2017-01-01

The practicum is internationally recognised as a valuable component of teacher education. It is an opportunity for pre-service teachers to develop teaching skills in authentic ways and pursue professional inquiry into practice. While extensive research has been conducted into the practicum generally, little research focuses on the practicum…

Negotiating Contradictions in Developing Teacher Identity during the EAL Practicum in Australia

ERIC Educational Resources Information Center

Nguyen, Minh Hue

2017-01-01

This paper reports on how Maria (pseudonym), a non-native English speaker (NNES) and preservice teacher (PST) of English as an additional language (EAL), developed her professional identity during the practicum in an Australian secondary school. Drawing on activity theory, the study identified contradictions in Maria's practicum activity and…

Practicum in adapted physical activity: a Dewey-inspired action research project.

PubMed

Standal, Øyvind; Rugseth, Gro

2014-07-01

The purpose of this study was to investigate what adapted physical activity (APA) students learn from their practicum experiences. One cohort of APA students participated, and data were generated from an action research project that included observations, reflective journals, and a focus group interview. The theoretical framework for the study was Dewey's and Wackerhausen's theories of reflections. The findings show the objects of students' reflections, the kind of conceptual resources they draw on while reflecting, and their knowledge interests. In addition, two paradoxes are identified: the tension between reflecting from and on own values, and how practicum as a valued experience of reality can become too difficult to handle. In conclusion, we reflect on how practicum learning can be facilitated.

Research Practicum in Rehabilitation Counselor Education: Learning Research through Hands-on Experience

ERIC Educational Resources Information Center

Miller, Susan M.; Rintelmann, Kristen

2007-01-01

The purpose of this paper is to discuss the research thesis as an educational tool and to propose the research practicum as an alternative to the thesis in rehabilitation counselor education programs. The research practicum has the potential to become an important learning opportunity which will provide rehabilitation counseling students with…

Development of an Instrument Measuring Student Teachers' Perceived Stressors about the Practicum

ERIC Educational Resources Information Center

Kokkinos, Constantinos M.; Stavropoulos, George; Davazoglou, Aggeliki

2016-01-01

The Stressors about Practicum Inventory, a self-report measure of perceived stressors about the practicum, was designed to provide those responsible for the training of primary school teachers with an informative, inexpensive and psychometrically sound tool. The present study describes the development and validation of the 94-item inventory in a…

Developing Teaching Skills through the School Practicum in Turkey: A Metasynthesis Study

ERIC Educational Resources Information Center

Tas, Mükerrem Akbulut; Karabay, Aysegül

2016-01-01

Using a metasynthesis approach, this study examined general teaching skills in previous studies on school practicum. The results and suggestions from 53 qualitative primary research studies that focused on school practicum in Turkey were reviewed. Data were collected using document analysis and content analysis using the NVivo10 programme. The…

The Teaching Practicum as a Locus of Multi-Leveled, School-Based Transformation

ERIC Educational Resources Information Center

El Kadri, Michele Salles; Roth, Wolff-Michael

2015-01-01

The teaching practicum is often considered as a compulsory activity for enculturating new members into the teacher community by providing opportunities to experience teaching in action. However, the practicum is rarely conceptualized in terms of its transformative potential. In this study, we report the results of a two-year ethnography study of a…

A case study of sea breeze blocking regulated by sea surface temperature along the English south coast

NASA Astrophysics Data System (ADS)

Sweeney, J. K.; Chagnon, J. M.; Gray, S. L.

2013-09-01

The sensitivity of sea breeze structure to sea surface temperature (SST) and coastal orography is investigated in convection-permitting Met Office Unified Model simulations of a case study along the south coast of England. Changes in SST of 1 K are shown to significantly modify the structure of the sea breeze. On the day of the case study the sea breeze was partially blocked by coastal orography, particularly within Lyme Bay. The extent to which the flow is blocked depends strongly on the static stability of the marine boundary layer. In experiments with colder SST, the marine boundary layer is more stable, and the degree of blocking is more pronounced. The implications of prescribing fixed SST from climatology in numerical weather prediction model forecasts of the sea breeze are discussed.

A morning transition case between the land and the sea breeze regimes

NASA Astrophysics Data System (ADS)

Jiménez, Maria A.; Simó, Gemma; Wrenger, Burkhard; Telisman-Prtenjak, Maja; Guijarro, Jose A.; Cuxart, Joan

2015-04-01

To better understand the diurnal cycle of the Sea-Breeze (SB) in the island of Mallorca, during September 2013 the Mallorca Sea Breeze experimental field campaign (MSB13) took place in the Campos basin (located in the south side of the island). Measurements in the lower boundary layer (captive balloon and multicopter) and close to the surface were taken in a site close to the coast (500m inland). In this work an observed morning transition of the SB is further analysed through the observations and a high-resolution mesoscale simulation of this selected case. With the combined inspection of model results and observations, it is found that during the night-time the air flows out of the island: a land-breeze is found near the coast and downslope winds at the mountain slopes. After sunrise and during the previous phase (0600-0800 UTC) the temperature difference between land and sea is reduced meanwhile the wind has the land-breeze direction. During the preparatory phase (0800-1000 UTC) the land surface temperature is warmer than the sea and the wind weakens and veers towards the SB direction. Finally, during the development phase (1000-1200 UTC) the SB front propagates through the center of the Campos basin to the end of the basin, enhanced by the mountain upslope winds. Therefore, the radiative warming stops. The temperature, momentum and TKE budgets are used to understand the most relevant physical processes involved in each of the phases.

Genetic algorithm to solve the problems of lectures and practicums scheduling

NASA Astrophysics Data System (ADS)

Syahputra, M. F.; Apriani, R.; Sawaluddin; Abdullah, D.; Albra, W.; Heikal, M.; Abdurrahman, A.; Khaddafi, M.

2018-02-01

Generally, the scheduling process is done manually. However, this method has a low accuracy level, along with possibilities that a scheduled process collides with another scheduled process. When doing theory class and practicum timetable scheduling process, there are numerous problems, such as lecturer teaching schedule collision, schedule collision with another schedule, practicum lesson schedules that collides with theory class, and the number of classrooms available. In this research, genetic algorithm is implemented to perform theory class and practicum timetable scheduling process. The algorithm will be used to process the data containing lists of lecturers, courses, and class rooms, obtained from information technology department at University of Sumatera Utara. The result of scheduling process using genetic algorithm is the most optimal timetable that conforms to available time slots, class rooms, courses, and lecturer schedules.

78 FR 62300 - Prairie Breeze Wind Energy LLC; Supplemental Notice That Initial Market-Based Rate Filing...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-15

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. ER14-25-000] Prairie Breeze Wind Energy LLC; Supplemental Notice That Initial Market-Based Rate Filing Includes Request for Blanket... Breeze Wind Energy LLC's application for market-based rate authority, with an accompanying rate schedule...

Soil Moisture, Coastline Curvature, and Sea Breeze Initiated Precipitation Over Florida

NASA Technical Reports Server (NTRS)

Baker, R. David; Lynn, Barry H.; Boone, Aaron; Tao, Wei-Kuo

1999-01-01

Land surface-atmosphere interaction plays a key role in the development of summertime convection and precipitation over the Florida peninsula. Land-ocean temperature contrasts induce sea-breeze circulations along both coasts. Clouds develop along sea-breeze fronts, and significant precipitation can occur during the summer months. However, other factors such as soil moisture distribution and coastline curvature may modulate the timing, location, and intensity of sea breeze initiated precipitation. Here, we investigate the role of soil moisture and coastline curvature on Florida precipitation using the 3-D Goddard Cumulus Ensemble (GCE) cloud model coupled with the Parameterization for Land-Atmosphere-Cloud Exchange (PLACE) land surface model. This study utilizes data from the Convection and Precipitation Electrification Experiment (CaPE) collected on 27 July 1991. Our numerical simulations suggest that a realistic distribution of soil moisture influences the location and intensity of precipitation but not the timing of precipitation. In contrast, coastline curvature affects the timing and location of precipitation but has little influence on peak rainfall rates. However, both factors (soil moisture and coastline curvature) are required to fully account for observed rainfall amounts.

Unveiling Pre-Service Teachers' Attitudes toward Teaching: The Role of Pedagogical Practicums

ERIC Educational Resources Information Center

Morales Cortés, Yimer Andrés

2016-01-01

This article reports a research developed at Universidad Pedagógica y Tecnológica de Colombia with a group of pre-service teachers that was immersed in an English teaching practicum. The main purpose of this inquiry was to find out the role that practicum exerted on novice teachers' attitudes towards teaching. Data were collected through…

Nearshore Coastal Dynamics on a Sea-Breeze Dominated Micro-Tidal Beach (NCSAL)

NASA Astrophysics Data System (ADS)

Torres-Freyermuth, A.; Puleo, J. A.; Ruiz de Alegría-Arzaburu, A.; Figlus, J.; Mendoza, T.; Pintado-Patino, J. C.; Pieterse, A.; Chardon-Maldonado, P.; DiCosmo, N. R.; Wellman, N.; Garcia-Nava, H.; Palemón-Arcos, L.; Roberts, T.; López-González, J.; Bravo, M.; Ojeda, E.; Medellín, G.; Appendini, C. M.; Figueroa, B.; González-Leija, M.; Enriquez, C.; Pedrozo-Acuña, A.; Salles, P.

2014-12-01

A comprehensive field experiment devoted to the study of coastal processes on a micro-tidal beach was conducted from March 30th to April 12th 2014 in Sisal, Yucatán México. Wave conditions in the study area are controlled by local (i.e., sea-breezes) and meso-scale (i.e., Nortes) meteorological events. Simultaneous measurements of waves, tides, winds, currents, sediment transport, runup, and beach morphology were obtained in this experiment. Very dense nearshore instrumentation arrays allow us the study of the cross-/along- shore variability of surf/swash zone dynamics during different forcing conditions. Strong sea-breeze wind events produced a diurnal cycle with a maximum wind speed of 14 m/s. The persistent sea-breeze system forces small-amplitude (Hs<1 m) short-period (Tp<4 s) NE waves approaching with a high incidence wave angle. These wave conditions drive westward alongshore currents of up to 0.6 m/s in the inner surf zone and hence produce an active sediment transport in the swash zone. On the other hand, the more energetic (Hs>1 m) Norte event, lasting 48 hours, reached the coast on April 8th generating a long-period swell (Tp>10 s) arriving from the NNW. This event induced an eastward net sediment transport across a wide surf zone. However, long-term observations of sand impoundment at a groin located near the study area suggests that the net sediment transport in the northern Yucatan peninsula is controlled by sea-breeze events and hence swash zone dynamics play an important role in the net sediment budget of this region. A comparative study of surf and swash zone dynamics during both sea-breeze and Norte events will be presented. The Institute of Engineering of UNAM, throughout an International Collaborative Project with the University of Delaware, and CONACYT (CB-167692) provided financial support. The first author acknowledges ONR Global for providing financial support throughout the Visiting Scientist Program.

A Database Practicum for Teaching Database Administration and Software Development at Regis University

ERIC Educational Resources Information Center

Mason, Robert T.

2013-01-01

This research paper compares a database practicum at the Regis University College for Professional Studies (CPS) with technology oriented practicums at other universities. Successful andragogy for technology courses can motivate students to develop a genuine interest in the subject, share their knowledge with peers and can inspire students to…

Solar breeze power package and saucer ship

DOE Office of Scientific and Technical Information (OSTI.GOV)

Veazey, S. E.

1985-11-12

A solar breeze power package having versatile sail and windmast options useful both on land and sea and especially useful in the saucer ship type design. The Vertical Axis Wind Turbine (VAWT) of the several Darrieus designs in conjunction with roll-up or permanently mounted solar cells combine in a hybrid or are used separately to provide power to a battery bank or other storage device.

Bridging the Hemispheres through the Use of Technology: International Collaboration in Social Work Training

ERIC Educational Resources Information Center

Rautenbach, John Victor; Black-Hughes, Christine

2012-01-01

The social work programs of the University of Fort Hare, East London, South Africa, and Minnesota State University, Mankato, United States, began using various technologies in 2007 to facilitate interaction. This project included conducting practicum supervision and seminars via videoconferencing (using Breeze, Adobe Connect, and Skype) and…

Mathematics Practicum at St. Olaf College: Project-Based Learning through Academic Civic Engagement

ERIC Educational Resources Information Center

Sanft, Rebecca; Ziegler-Graham, Kathryn

2018-01-01

The Mathematics Practicum has been offered at St. Olaf College for over 30 years. The Practicum is a 4-week, January Interim course where three teams of five students work on consulting problems solicited from area businesses, government agencies, and non-profit organizations. These problems have significant mathematical, statistical, and…

Issues and Concerns Faced by Undergraduate Language Student Teachers during Teaching Practicum Experiences

ERIC Educational Resources Information Center

Ali, Mohd Sofi; Othman, Abdul Jalil; Karim, Abdul Faruk Abdul

2014-01-01

This study examined specific issues and concerns faced by Bachelor of Education student teachers majoring in Language and Literature during their 12-week teaching practicum experience. Specifically, three main areas of concerns were examined. They were: (1) specific issues and concerns related to the implementation of teaching practicum faced by…

Practicum-Based Approach to Bridge between Information-Systems Industry Expectations and Graduates Qualifications

ERIC Educational Resources Information Center

Lavy, Ilana

2017-01-01

In this study, a practicum-based approach to bridge the gap between industry expectations and Information Systems graduates skills is presented and discussed. Students participate in the practicum project during their last study year, and take part in various professional activities in the industry in accordance with their professional aspirations…

Gulf Breeze, FL Lab--Office of Research and Development

EPA Pesticide Factsheets

The Gulf Breeze lab is recognized as a leader in advancing scientific knowledge concerning the effects of human-made stressors on the ecosystems of the Gulf Coast, and the impacts of those effects on the health and well-being of people and communities.

Evaluating Trainees in the Counseling Practicum.

ERIC Educational Resources Information Center

Meyerson, Roberta C.

A study was made to determine the procedures which supervisors and instructors of counseling practica currently use to evaluate the counseling effectiveness of masters and doctoral level practicum students. Inquiry was also made about the solutions adopted when a student is considered ineffective. The survey elicited responses from 89 individuals,…

The impact of land and sea surface variations on the Delaware sea breeze at local scales

NASA Astrophysics Data System (ADS)

Hughes, Christopher P.

The summertime climate of coastal Delaware is greatly influenced by the intensity, frequency, and location of the local sea breeze circulation. Sea breeze induced changes in temperature, humidity, wind speed, and precipitation influence many aspects of Delaware's economy by affecting tourism, farming, air pollution density, energy usage, and the strength, and persistence of Delaware's wind resource. The sea breeze front can develop offshore or along the coastline and often creates a near surface thermal gradient in excess of 5°C. The purpose of this dissertation is to investigate the dynamics of the Delaware sea breeze with a focus on the immediate coastline using observed and modeled components, both at high resolutions (~200m). The Weather Research and Forecasting model (version 3.5) was employed over southern Delaware with 5 domains (4 levels of nesting), with resolutions ranging from 18km to 222m, for June 2013 to investigate the sensitivity of the sea breeze to land and sea surface variations. The land surface was modified in the model to improve the resolution, which led to the addition of land surface along the coastline and accounted for recent urban development. Nine-day composites of satellite sea surface temperatures were ingested into the model and an in-house SST forcing dataset was developed to account for spatial SST variation within the inland bays. Simulations, which include the modified land surface, introduce a distinct secondary atmospheric circulation across the coastline of Rehoboth Bay when synoptic offshore wind flow is weak. Model runs using high spatial- and temporal-resolution satellite sea surface temperatures over the ocean indicate that the sea breeze landfall time is sensitive to the SST when the circulation develops offshore. During the summer of 2013 a field campaign was conducted in the coastal locations of Rehoboth Beach, DE and Cape Henlopen, DE. At each location, a series of eleven small, autonomous thermo-sensors (i

The Role of the Prepracticum in Lessening Student Teacher Stress: Student Teachers' Perceptions of Stress during Practicum

ERIC Educational Resources Information Center

Danyluk, Patricia

2013-01-01

Research on the student teaching practicum indicates that it is a time of enormous stress. The purpose of this study was to gather information from student teachers regarding their perceptions of stress while in the midst of their practicum. The questions were designed to gather information that could be used to create a less stressful practicum.…

Diagnosis of sea breeze cases over the Metropolitan Area of São Paulo with the WRF model

NASA Astrophysics Data System (ADS)

Homann, C.; Freitas, E. D.

2013-05-01

The sea breeze is a great responsible for the organization of severe weather events, climate patterns and air pollution dispersion over the Metropolitan Area of São Paulo (MASP), being the knowledge about its correct predictability very important in the region. The Weather Research and Forecasting (WRF) mesoscale model was used to simulate some events of sea breeze propagation over the MASP during the winter season of 2009 (18th and 20th june, 29th august, 02nd September) with the objective to analyze the skill of the model on the predictability of this events using the default parameterizations available in the model and identify some flaws and possible adjustments to be made in the model. For this purpose, the simulation results were compared with the observed velocity and wind direction collected in the "Campo de Marte" Airport - SP. The model had a good response for all simulated days, where the horizontal wind and the vapor mixing ratio indicating correctly the sea breeze arrival over the region. Another important feature observed in the wind moisture fields was the moments that the sea breeze reaches different parts of MASP in response to the Urban Heat Island effect, which can accelerate or prevent the sea breeze propagation depending on location, as observed in other studies, and the relative position of the metropolitan area with respect to the sea-shore and the topography of the region. It was observed that the sea-breeze front reaches the southwest portion of MASP approximately two hours before it reaches the northwest portion.

Student Teachers' Computer Use during Practicum.

ERIC Educational Resources Information Center

Wang, Yu-mei; Holthaus, Patricia

This study was designed to investigate the use of computers by student teachers in their practicums. Student teachers (n=120) in two public universities in the United States answered a questionnaire that covered: the manner and frequency of computer use, student teachers' perception of their training, their attitudes toward the role of the…

Supporting Inclusive Practicum Experiences for International Students across the Social Sciences: Building Industry Capacity

ERIC Educational Resources Information Center

Felton, Kathleen; Harrison, Gai

2017-01-01

Practicum experiences are critical learning environments for developing requisite skills, knowledge, behaviours and attitudes across the professions. Evidence suggests that international students in professional social and behavioural science programs struggle across a number of dimensions while on practicum. Key issues for these students coalesce…

Impact of Bay-Breeze Circulations on Surface Air Quality and Boundary Layer Export

NASA Technical Reports Server (NTRS)

Loughner, Christopher P.; Tzortziou, Maria; Follette-Cook, Melanie; Pickering, Kenneth E.; Goldberg, Daniel; Satam, Chinmay; Weinheimer, Andrew; Crawford, James H.; Knapp, David J.; Montzka, Denise D.;

A Coastal Bay Summer Breeze Study, Part 1: Results of the Quiberon 2006 Experimental Campaign

NASA Astrophysics Data System (ADS)

Mestayer, Patrice G.; Calmet, Isabelle; Herlédant, Olivier; Barré, Sophie; Piquet, Thibaud; Rosant, Jean-Michel

2018-04-01

The Quiberon 2006 experiment was launched to document the onset and development of land and sea breezes over a semi-circular coastal bay propitious to inshore sailing competitions. The measurements were taken during the 2 weeks of 16-28 June 2006. Micrometeorological variables were recorded at three shore sites around the bay using turbulence sensors on 10-30-m high masts, on four instrumented catamarans at selected sites within the bay, and at a fourth shore site with a Sodar. Synoptic data and local measurements are analyzed here from the point of view of both micrometeorologists and competition skippers, testing in particular the empirical rules of breeze veering and backing according to the wind direction with respect to the coastline orientation at the mesoscale (the quadrant theory). Our analysis focuses on the patterns of lower-altitude wind direction and speed around the bay and over the water basin, and the temporal variations during the periods of the breeze onset, establishment and thermal reinforcement. In offshore synoptic-flow conditions (quadrants 1 and 2), the clockwise rotation of the surface flow had a very large amplitude, reaching up to 360°. The breeze strength was negatively correlated to that of the synoptic wind speed. In conditions of onshore synoptic flow from the west (quadrant 3) at an angle to the mainland coast but perpendicular to the Quiberon peninsula, the rotation of the flow was backwards in the early morning and clockwise during the day with a moderate amplitude (40°-50°) around the synoptic wind direction. As the surface wind speed was much larger than the synoptic wind speed, such a case we have designated as a "synoptic breeze". The breeze onset was shown to fail several times under the influence of weak non-thermal events, e.g., the passage of an occluded front or clouds or an excess of convection. Finally, several local-scale influences of the complex coastal shape appeared in our measurements, e.g., wind fanning in the

[Formula: see text]Official Position of the American Academy of Clinical Neuropsychology (AACN): Guidelines for Practicum Training in Clinical Neuropsychology.

PubMed

Nelson, Aaron P; Roper, Brad L; Slomine, Beth S; Morrison, Chris; Greher, Michael R; Janusz, Jennifer; Larson, Jennifer C; Meadows, Mary-Ellen; Ready, Rebecca E; Rivera Mindt, Monica; Whiteside, Doug M; Willment, Kim; Wodushek, Thomas R

2015-01-01

Practical experience is central to the education and training of neuropsychologists, beginning in graduate school and extending through postdoctoral fellowship. However, historically, little attention has been given to the structure and requirements of practicum training in clinical neuropsychology. A working group of senior-level neuropsychologists, as well as a current postdoctoral fellow, all from a diverse range of settings (The AACN Practicum Guidelines Workgroup), was formed to propose guidelines for practicum training in clinical neuropsychology. The Workgroup reviewed relevant literature and sought input from professional organizations involved in education and training in neuropsychology. The proposed guidelines provide a definition of practicum training in clinical neuropsychology, detail entry and exit criteria across competencies relevant to practicum training in clinical neuropsychology, and discuss the relationship between doctoral training programs and practicum training sites. The proposed guidelines also provide a methodology for competency-based evaluation of clinical neuropsychology practicum trainees and outline characteristics and features that are integral to an effective training environment. Although the guidelines discussed below may not be implemented in their entirety across all clinical neuropsychology practicum training sites, they are consistent with the latest developments in competency-based education.

Local and Global--Conflicting Perspectives? The Place of Overseas Practicum in Preservice Teacher Education

ERIC Educational Resources Information Center

Cruickshank, Kenneth; Westbrook, Ros

2013-01-01

International practicum is disappearing from teacher education programs with the increasing pressures for "local experience". International practicum is seen as too different from local contexts to develop preservice teachers to meet professional standards. This study explores the teaching development of a group of 24 preservice teachers…

Profile of Students Uninterested in Practicum Class at Faculty of Engineering Universitas Negeri Surabaya

NASA Astrophysics Data System (ADS)

Munoto; Sondang, Meini; Satriana, FMS

2018-04-01

This study aims to determine the characteristics of students who were uninterested in attending practicum classes. This study applied naturalistic qualitative research methods using participatory observation and interviews. The data validity was ensured by triangulation, detailed description, length of observation time, as well as details and thorough observation. The data were analyzed using domain analysis and followed by conducting taxonomic, component, and thematic analyses. The results of the study indicate that faineant students show a negative behavior while attending laboratory practicums. They have a lack of motivation, effective interaction, and attention. The cognitive abilities vary from low to high. Other causes on how the aspects of the study were low were found as well, therefore improving those aspects allows students to raise their interest in practicum classes. The impact is to create well-skilled vocational teachers in conducting practicum classes in vocational schools and to make graduates better-prepared for the workforce.

Examining the eastern Amazon Basin breeze circulations, channeling and boundary layer properties using altitude controlled meteorological balloons

NASA Astrophysics Data System (ADS)

Fitzjarrald, D. R.; Voss, P. B.; Silva, R. D.; Callahan, S.; Dewald, A.; do Vale, R. S.

2017-12-01

During the period August 24-28, 2016, in a delayed component the GO-Amazon Project, we launched nine altitude-controlled free balloons (CMET). Smaller than typical rawinsondes, CMET are equipped with altitude control, global communication via Iridium satellite, and aspirated sensors. The aims of our effort were to examine the interactions among convective boundary layer and dual river breeze circulations near the confluence of the Tapajos and Amazon Rivers in the eastern Basin. The week-long field campaign was timed to examine the reestablishment of the breeze circulations shortly after the passage of a strong instability line on August 22. Nine CMET were launched at the Curua-Una hydroelectric dam (2.8S; 54.3W), timed to encounter the Tapajos river breeze front by late afternoon. Soundings were made to establish the thickness of interface between the easterly trade and westerly Tapajos breeze circulation. Careful use of sounding strategies allowed these free balloons to track along the northerly channeled flow in the lowest 300 m above the River. Following the river encounter, balloons tracked to the west, sounding to describe the diurnal course of boundary layer in the forest west of the Tapajos River. The longest flight traveled more than 770 km over three days and twice rested overnight in the rain forest canopy. Ancillary data from surface climate and flux stations as well as the Santarem radiosonde, satellite images will be used to illustrate how the breeze circulations are seen near the surface and how they were disrupted by larger-scale events. Comparisons with HYSPLIT trajectories will illustrate how sensitive real trajectories are to the refraction that the encounter with the breeze effects.

An analysis of music therapy student practicum behaviors and their relationship to clinical effectiveness: an exploratory investigation.

PubMed

Darrow, A A; Johnson, C M; Ghetti, C M; Achey, C A

2001-01-01

The purpose of the present study was to investigate specific clinical behaviors exhibited by music therapy students in their 1st through 4th semesters of practicum. A secondary purpose of the study was to determine if a relationship exists between therapy students' behaviors and their assessed clinical success. Participants were instructed to submit 20-minutes of videotape from one practicum session, chosen at random from the current practicum semester. Two trained observers then viewed the videotapes and simultaneously recorded the occurrence and duration of practicum student behaviors using SCRIBE, a data collection computer program. The SCRIBE program was configured to include 5 broad categories of therapist behaviors: musical behaviors (singing, playing, listening), physical behaviors (such as hand-over-hand assistance, cueing, or clapping), verbal behaviors (therapy-related verbal interactions or other), a combination of two of the above, and other nonspecified behaviors. The percentage of time practicum students exhibited behaviors within in each category was calculated for all session segments. These same videotapes were also evaluated by 2 professional board certified music therapists who were unfamiliar with the practicum students. Students were assigned an overall rating for clinical effectiveness. Evaluators were also asked to provide comments related to their ratings. A descriptive analysis of clinical behaviors indicate that students spend nearly 40% of their practicum time engaged in musical behaviors and over 50% of their time engaged in verbal behaviors. No significant differences were found in the behaviors exhibited by students in the various practicum levels; however, behavioral differences were found for individual student therapists. Additionally, no relationship was found between students' behaviors and their clinical effectiveness. An analysis of comments by the evaluators indicates that the quantity of musical behaviors does not affect

Building professional competence in dental hygiene students through a community-based practicum.

PubMed

Yoon, M N; Compton, S M

2017-11-01

As Canadians age, there is an increased need for oral health professionals specializing in services for this unique population. Dental hygiene students require exposure to this population to develop professional competencies. This study investigated the dimensions of professional competence that were developed through a practicum for dental hygiene students in long-term care settings while working with older adults. Nine dental hygiene students were recruited across two cohorts. All students completed reflective journals describing their practicum experiences. Five students also participated in an audio-recorded focus group and completed a pre-focus group questionnaire. Additionally, the practicum course coordinator completed an audio-recorded interview. Transcripts and journals were coded using a constant comparative approach and themes were identified. Students described developing client-focused skills, such as effective verbal and non-verbal communication with older adults with dementia. Context-based learning was also a large part of the competency development for the practicum students. Understanding the care environment within which these residents lived helped students to understand and empathize why oral health may not be prioritized. Students also developed an understanding of the work of other health professionals in the settings and improved their abilities to communicate with other healthcare providers. However, students recognized that the utility of those interprofessional skills in private practice may be limited. Dental hygiene students developed personal and ethical competencies during practicum that are highly transferrable across professional settings. Exposure of students to older adult populations in long-term care may increase the likelihood of dental hygienists working in this area. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Wireless Handhelds to Support Clinical Nursing Practicum

ERIC Educational Resources Information Center

Wu, Cheng-Chih; Lai, Chin-Yuan

2009-01-01

This paper reports our implementation and evaluation of a wireless handheld learning environment used to support a clinical nursing practicum course. The learning environment was designed so that nursing students could use handhelds for recording information, organizing ideas, assessing patients, and also for interaction and collaboration with…

A Guide to Laboratory Practicum on Mechanics

NASA Astrophysics Data System (ADS)

Rusu, A. S.; Rusu, S. S.; Pirtac, C.

2012-12-01

The Guide represent a Laboratory practicum in mechanics for students from the Technical University of Moldova. The works are modernized as compared with older ones put in 1964 by Computer assistance. Each work contains theoretical framework, a work instruction and control questions. The Guide contains 27 figures.

Nursing student and professor perceptions and assessments of the achievement of practicum competencies: A mixed method approach.

PubMed

Fuentes-Pumarola, Concepció; Ballester-Ferrando, David; Gelabert-Vilella, Sandra; Bosch-Farré, Cristina; Malagón-Aguilera, M Carme; Rascón-Hernán, Carolina; Bonmatí-Tomàs, Anna; Fernandez-Peña, Rosario

2016-10-01

Within the context of the European Higher Education Area's requirement of competency-based assessments, the objective of the present study was to evaluate the Nursing Degree Practicum experience at the University of Girona (Spain) and ascertain student and faculty perceptions of the degree of competency achieved as a result of the practicum. This cross-sectional, descriptive, study combined quantitative analysis of a questionnaire and qualitative analysis of focus group comments. In the quantitative part of the study, 163 fourth-year nursing students completed the questionnaire; the qualitative analysis was derived from a focus group of 5 students and 5 professors. On the questionnaire, overall practicum evaluation was 8.39 on a 10-point Likert scale; scores evaluating the nurse mentor/instructor and nursing professor were 8.43 and 7.98, respectively. The geriatrics practicum experience received the lowest overall score (7.81), while the surgical practicum received the lowest score on the adequacy of knowledge acquired in the classroom in previous courses (5.54). The best scores were earned by the mental health and intensive/emergency care practicum experiences (a mean of 9.05 and 8.70, respectively). Students and professors in the focus group agreed that the practicum met the Nursing degree program's competency goals, highlighting practical activity as the best methodology to evaluate competencies. Participants highlighted the importance of reflective practice and the role of the nurse mentor/instructor in student learning, and indicated that it is essential for the university and the health care centers where students take practicum courses to maintain a strong relationship and good communication. Finally, feedback from the nurse mentor/instructor and Nursing professor was very important to students, both to motivate them and to help them learn. Copyright © 2016 Elsevier Ltd. All rights reserved.

Student Perceptions of a Hands-on Practicum to Supplement an Online eHealth Course

PubMed Central

2012-01-01

Background Since 2000, the Centre for Online Health (COH) at The University of Queensland has offered a range of online eHealth courses at the undergraduate and postgraduate level. While online learning has a number of advantages, in some domains, it can present some challenges to the development of practical skills and experience. Objective To assess students’ perceptions of the value of an eHealth practicum. Methods To supplement our online learning program, we introduced an eHealth practicum component that aimed to expose students to a range of clinically relevant learning experiences. Subsequently, by means of a questionnaire, student perceptions of the practicum were assessed. Results Over two semesters, a total of 66 students participated in the eHealth practicum, and questionnaire responses were very positive. The majority of students agreed that the practicum allowed them to gain necessary skills in eHealth applications (59%) and provided them with an opportunity to explore ways of using different eHealth tools for the delivery of health care at a distance (62%). Conclusions The study shows that a practical component in eHealth teaching was well received by students. While online teaching is appropriate for providing knowledge, the opportunity to develop practical skills may encourage students to use eHealth techniques in their future practices. PMID:23246840

The Use of Per Session Clinical Assessment with Clients in a Mental Health Delivery System: An Investigation into How Clinical Mental Health Counseling Practicum Students and Practicum Instructors Use Routine Client Progress Feedback

ERIC Educational Resources Information Center

Yates, Chad Michael

2012-01-01

The purpose of this study was to investigate how clinical mental health counseling practicum students and practicum instructors use per session assessment feedback with clients they served at a university counseling center. Per session assessment and feedback has been shown to increase the treatment outcomes that counselors achieve while treating…

Between Signification and Illumination: Unfolding Understandings of an A/r/tographical Turn on Practicum

ERIC Educational Resources Information Center

Carter, Mindy R.; Irwin, Rita L.

2014-01-01

School associates (SA's), or cooperating teachers (CT's), have arguably been one of the most powerful influences on the teacher candidate's (TC) pre-service experience. For this reason, most studies about the practicum have focused on this relationship. However, while observing one visual art student's practicum as her Faculty Advisor (FA) for the…

Enhancing the Capabilities of Associate Teachers in the Practicum: A New Zealand Case Study

ERIC Educational Resources Information Center

Sewell, Alison; Hansen, Sally; Weir, Kama

2017-01-01

The practicum is critically important in initial teacher education. Yet too often, student-teachers are placed in schools where the associate teacher does not understand the mentoring component of their supervisory role. This study explores the impact of a school-university project on the associate teachers' mentoring in the practicum and in their…

Field Observations of Swash-Zone Dynamics on a Sea-Breeze Dominated Beach at the Yucatán Peninsula, México

NASA Astrophysics Data System (ADS)

Chardon-Maldonado, P.; Puleo, J. A.; Torres-Freyermuth, A.

2016-02-01

Sea breezes can modify the nearshore processes and alter beach morphology depending on the geographical location. Prior studies have shown that surf zone wave energy intensifies during strong sea-breeze conditions (wind speeds > 10 ms-1) and the impact on the coast can be similar to a small storm. However, few research efforts have investigated the coastal dynamics on sea-breeze dominated beaches (e.g., Masselink and Pattiaratchi, 1998, Mar. Geol.; Pattiaratchi et al., 1997, Cont. Shelf Res.) and, to the authors' knowledge, only one study has focused on swash-zone processes (Sonu et al., 1973, EOS). A field study was performed on a microtidal, low wave energy, sea-breeze dominated sandy beach in order to investigate the effects of local (sea breeze) and synoptic (storm) scale meteorological events on swash-zone dynamics. In-situ measurements of swash-zone hydrodynamics and sediment transport processes were collected from March 31st to April 12th, 2014 in Sisal, Yucatán located on the northern coast of the Yucatán Peninsula. Flow velocities and suspended sediment concentrations were measured concurrently, at multiple cross-shore and alongshore locations, using Vectrino-II profiling velocimeters and optical backscatter sensors, respectively. The high resolution data allowed the quantification of bed shear stress, turbulent dissipation rate, sediment loads and sediment flux during a mesoscale frontal system (cold-front passage referred to as an El Norte) and local sea-breeze cycles. Field observations showed that strong swash-zone bed shear stresses, turbulence intensity and sediment suspension occur during energetic conditions (i.e., El Norte event). On the other hand, despite milder energy conditions during the sea-breeze events, the alongshore component of bed-shear stresses and velocities can be significant owing to the high incidence wave angle associated with the sea-breeze system in the study area. The increased forcing in the swash zone induced sediment

A case study of sea breeze blocking regulated by sea surface temperature along the English south coast

NASA Astrophysics Data System (ADS)

Sweeney, J. K.; Chagnon, J. M.; Gray, S. L.

2014-05-01

The sensitivity of sea breeze structure to sea surface temperature (SST) and coastal orography is investigated in convection-permitting Met Office Unified Model simulations of a case study along the south coast of England. Changes in SST of 1 K are shown to significantly modify the structure of the sea breeze immediately offshore. On the day of the case study, the sea breeze was partially blocked by coastal orography, particularly within Lyme Bay. The extent to which the flow is blocked depends strongly on the static stability of the marine boundary layer. In experiments with colder SST, the marine boundary layer is more stable, and the degree of blocking is more pronounced. Although a colder SST would also imply a larger land-sea temperature contrast and hence a stronger onshore wind - an effect which alone would discourage blocking - the increased static stability exerts a dominant control over whether blocking takes place. The implications of prescribing fixed SST from climatology in numerical weather prediction model forecasts of the sea breeze are discussed.

Possible impacts of the pre-monsoon dry line and sea breeze front on nocturnal rainfall over northeast Bangladesh

NASA Astrophysics Data System (ADS)

Stiller-Reeve, Mathew; Toniazzo, Thomas; Kolstad, Erik; Spengler, Thomas

2017-04-01

The northeast region of Bangladesh receives a large amount of rainfall before the large-scale monsoon circulation begins. For example, in April (a "pre-monsoon" month) 2010, 804 mm of rain fell in the regional capital Sylhet. It was the second wettest month of the entire year. From our conversations with the local people, we know that this pre-monsoon rainfall is extremely important to their livelihoods. We therefore need to understand it's triggering mechanisms. Several theories have been published, all of which are likely to be at play. However, in this work we look more closely at how the sea breeze front and prominent pre-monsoonal dry line in this region may play a role. If these mechanisms play a role in the convection, then it is likely that they trigger convection further afield, and then the resulting systems then propagate towards northeast Bangladesh. We believe this because rainfall associated with dry line/sea-breeze front convection often occurs during the late afternoon, but the rainfall over northeast Bangladesh shows a clear late-night/early-morning maxima. At present, the temporal and spatial resolution of the regional observations is inappropriate for examining these possible mechanisms. We therefore use a numerical model (WRF) to investigate the possible links between the convection and the sea breeze front and dry line. We use April 2010 as a case study since it was such a wet pre-monsoon month. The simulation shows that a sea breeze circulation often develops during the day in the coastal zone of Bangladesh and northeast India. After sunset the sea breeze front propagates inland pushing back the hot, dry air over India. On several days during the simulation, convection is triggered along the sea breeze front, which then propagates towards northeast Bangladesh and intensifies across the topography surrounding the Sylhet region. From our simulations, it appears that nocturnal convection over northeast Bangladesh is triggered by several

33 CFR 334.775 - Naval Air Station Pensacola, Pensacola Bay, Pensacola and Gulf Breeze, Fla.; naval restricted area.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 33 Navigation and Navigable Waters 3 2011-07-01 2011-07-01 false Naval Air Station Pensacola, Pensacola Bay, Pensacola and Gulf Breeze, Fla.; naval restricted area. 334.775 Section 334.775 Navigation... RESTRICTED AREA REGULATIONS § 334.775 Naval Air Station Pensacola, Pensacola Bay, Pensacola and Gulf Breeze...

33 CFR 334.775 - Naval Air Station Pensacola, Pensacola Bay, Pensacola and Gulf Breeze, Fla.; naval restricted area.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Naval Air Station Pensacola, Pensacola Bay, Pensacola and Gulf Breeze, Fla.; naval restricted area. 334.775 Section 334.775 Navigation... RESTRICTED AREA REGULATIONS § 334.775 Naval Air Station Pensacola, Pensacola Bay, Pensacola and Gulf Breeze...

A numerical study of the effects of a large sandbar upon sea breeze development

NASA Technical Reports Server (NTRS)

Kessler, R. C.; Pielke, R. A.; Mcqueen, J.; Eppel, D.

1985-01-01

Two-dimensional numerical simulations of sea breeze development over a large sandbar on the North Sea coast of Germany are reported. The numerical model used in these experiments contains a detailed treatment of soil moisture, which allows evaluation of the effects of differential surface characteristics on the airflow pattern. Results of the simulations indicate that the contrast between the moist sandbar and adjacent dry land, the tidal inundation of the sandbar, and the westward penetration of the Baltic sea breeze play important roles in the development of mesoscale airflow patterns in the sandbar region.

Effects of Flipped Learning Using Online Materials in a Surgical Nursing Practicum: A Pilot Stratified Group-Randomized Trial.

PubMed

Lee, Myung Kyung; Park, Bu Kyung

2018-01-01

This study examined the effect of flipped learning in comparison to traditional learning in a surgical nursing practicum. The subjects of this study were 102 nursing students in their third year of university who were scheduled to complete a clinical nursing practicum in an operating room or surgical unit. Participants were randomly assigned to either a flipped learning group (n = 51) or a traditional learning group (n = 51) for the 1-week, 45-hour clinical nursing practicum. The flipped-learning group completed independent e-learning lessons on surgical nursing and received a brief orientation prior to the commencement of the practicum, while the traditional-learning group received a face-to-face orientation and on-site instruction. After the completion of the practicum, both groups completed a case study and a conference. The student's self-efficacy, self-leadership, and problem-solving skills in clinical practice were measured both before and after the one-week surgical nursing practicum. Participants' independent goal setting and evaluation of beliefs and assumptions for the subscales of self-leadership and problem-solving skills were compared for the flipped learning group and the traditional learning group. The results showed greater improvement on these indicators for the flipped learning group in comparison to the traditional learning group. The flipped learning method might offer more effective e-learning opportunities in terms of self-leadership and problem-solving than the traditional learning method in surgical nursing practicums.

Effects of Flipped Learning Using Online Materials in a Surgical Nursing Practicum: A Pilot Stratified Group-Randomized Trial

PubMed Central

Lee, Myung Kyung

2018-01-01

Objectives This study examined the effect of flipped learning in comparison to traditional learning in a surgical nursing practicum. Methods The subjects of this study were 102 nursing students in their third year of university who were scheduled to complete a clinical nursing practicum in an operating room or surgical unit. Participants were randomly assigned to either a flipped learning group (n = 51) or a traditional learning group (n = 51) for the 1-week, 45-hour clinical nursing practicum. The flipped-learning group completed independent e-learning lessons on surgical nursing and received a brief orientation prior to the commencement of the practicum, while the traditional-learning group received a face-to-face orientation and on-site instruction. After the completion of the practicum, both groups completed a case study and a conference. The student's self-efficacy, self-leadership, and problem-solving skills in clinical practice were measured both before and after the one-week surgical nursing practicum. Results Participants' independent goal setting and evaluation of beliefs and assumptions for the subscales of self-leadership and problem-solving skills were compared for the flipped learning group and the traditional learning group. The results showed greater improvement on these indicators for the flipped learning group in comparison to the traditional learning group. Conclusions The flipped learning method might offer more effective e-learning opportunities in terms of self-leadership and problem-solving than the traditional learning method in surgical nursing practicums. PMID:29503755

International Students' Experience of Practicum in Teacher Education: An Exploration through Internationalisation and Professional Socialisation

ERIC Educational Resources Information Center

Barton, Georgina M.; Hartwig, Kay A.; Cain, Melissa

2015-01-01

This paper explores the practicum experience of international students studying in a teacher education course. Much research has investigated the experience of international students during their degree experience but there is limited research that has addressed the practicum; a key component of teacher education. The research that does exist…

Teaching ESL in an Unfamiliar Context: International Students in a North American MA TESOL Practicum.

ERIC Educational Resources Information Center

Polio, Charlene; Wilson-Duffy, Carol

1998-01-01

Investigates the concerns and difficulties of international students from non-English speaking countries during the Teaching English as a Second Language (TESOL) practicum component of a master's TESOL program. Interviews with students before, during, and after the practicum and examination of their journals and assignments indicated that they had…

Clients becoming teachers: Speech-language pathology students' understanding of rehabilitation following clinical practicum in a rehabilitation setting.

PubMed

Attrill, Stacie; Gunn, Simon

2010-04-01

There has been limited research investigating the conceptual development of rehabilitation in speech-language pathology (SLP) students. The aim of this study was to describe SLP students' understanding of rehabilitation following completion of a clinical practicum in a rehabilitation setting. This study was conducted using a qualitative approach according to grounded theory methodology. Semi-structured interviews were conducted with 10 SLP students who had completed a practicum in a rehabilitation setting. Interview data analysis revealed the emergence of five axial categories. Clients becoming teachers was identified as the core category, as the notion that clients were fundamental to students' understanding of rehabilitation occurred reliably throughout the data and related to all other categories. A theoretical model was proposed that demonstrated successive levels of support to students in the acquisition of their understanding of rehabilitation on practicum. Students' understanding of rehabilitation was derived from client-related interactions and factors experienced on practicum in rehabilitation settings. Rehabilitation practicum provided students with a rich and complex learning environment that may facilitate the development of the "core skills" identified for rehabilitation practice.

Practicum Training for Teachers of Struggling Readers

ERIC Educational Resources Information Center

Morris, Darrell

2011-01-01

Teachers who work with struggling beginning readers need a supervised training experience that leads them to understand both how reading ability develops and how to adapt instruction to meet the needs of individual children. The practicum, in which a teacher works with one struggling reader under the supervision of an experienced and expert…

The Effectiveness of an Embedded Approach to Practicum Experiences in Educational Leadership: Program Candidates' Perspectives

ERIC Educational Resources Information Center

Chandler, Mary; Chan, Tak Cheung; Jiang, Binbin

2013-01-01

This study examined how effective an embedded practicum experience in an educational leadership program in a Southeastern University is in serving the purpose of preparing educational leaders to meet future challenges. Findings of this study confirm practicum areas that met the educational demands and highlight areas that need improvement to…

Taking risks with a growth mindset: long-term influence of an elementary pre-service after school science practicum

NASA Astrophysics Data System (ADS)

Cartwright, T. J.; Hallar, B.

2018-02-01

In this study, we present the long-term influence of an after school science practicum associated with an elementary science methods course. The practicum or field experience could be considered a community-based service learning programme as it is situated both within and for the community. Study participants included eight third- and fifth-grade teachers who had participated in elementary science methods courses; four of these teachers participated in the after school teaching practicum while four participants experienced a more traditional observation-based elementary science practicum. All of these teachers were in their second or third year teaching which was 3-4 years after taking the methods course. Investigation methods included questionnaires, field observations and semi-structured, individual interviews. Teachers more regularly utilised reform-based teaching strategies and cited the after school teaching practicum as preparing them to use these strategies in their own classrooms. All teachers exhibited a growth mindset to some degree, but the after school practicum participants did demonstrate a wider use of reformed-based teaching strategies and a higher growth mindset. Elementary teachers perceive risk associated with these key aspects of instruction: (1) managing instruction and classroom management, (2) teaching science through guided inquiry, and (3) overcoming adoptions in other 'mandated' curriculum like math and reading.

Creative practicum leadership experiences in rural settings.

PubMed

Schoenfelder, Deborah Perry; Valde, Jill Gaffney

2009-01-01

Rural healthcare systems provide rich learning environments for nursing students, where strong nursing leaders manage care for people with diverse health problems across the lifespan. The authors describe the development, implementation, and evaluation of rural clinical leadership practicum, a prelicensure course that specifically focuses on the application of leadership concepts in small rural healthcare systems.

Effect of sea breeze circulation on aerosol mixing state and radiative properties in a desert setting

NASA Astrophysics Data System (ADS)

Derimian, Yevgeny; Choël, Marie; Rudich, Yinon; Deboudt, Karine; Dubovik, Oleg; Laskin, Alexander; Legrand, Michel; Damiri, Bahaiddin; Koren, Ilan; Unga, Florin; Moreau, Myriam; Andreae, Meinrat O.; Karnieli, Arnon

2017-09-01

Chemical composition, microphysical, and optical properties of atmospheric aerosol deep inland in the Negev Desert of Israel are found to be influenced by daily occurrences of sea breeze flow from the Mediterranean Sea. Abrupt increases in aerosol volume concentration and shifts of size distributions towards larger sizes, which are associated with increase in wind speed and atmospheric water content, were systematically recorded during the summertime at a distance of at least 80 km from the coast. Chemical imaging of aerosol samples showed an increased contribution of highly hygroscopic particles during the intrusion of the sea breeze. Besides a significant fraction of marine aerosols, the amount of internally mixed marine and mineral dust particles was also increased during the sea breeze period. The number fraction of marine and internally mixed particles during the sea breeze reached up to 88 % in the PM1-2. 5 and up to 62 % in the PM2. 5-10 size range. Additionally, numerous particles with residuals of liquid coating were observed by SEM/EDX analysis. Ca-rich dust particles that had reacted with anthropogenic nitrates were evidenced by Raman microspectroscopy. The resulting hygroscopic particles can deliquesce at very low relative humidity. Our observations suggest that aerosol hygroscopic growth in the Negev Desert is induced by the daily sea breeze arrival. The varying aerosol microphysical and optical characteristics perturb the solar and thermal infrared radiations. The changes in aerosol properties induced by the sea breeze, relative to the background situation, doubled the shortwave radiative cooling at the surface (from -10 to -20.5 W m-2) and increased by almost 3 times the warming of the atmosphere (from 5 to 14 W m-2), as evaluated for a case study. Given the important value of observed liquid coating of particles, we also examined the possible influence of the particle homogeneity assumption on the retrieval of aerosol microphysical characteristics

Enhancing Practicum Supervision with Asynchronous and Synchronous Technologies

ERIC Educational Resources Information Center

Teo, Yiong Hwee; McNamara, Sue; Romeo, Geoff; Gronn, Donna

2015-01-01

Three video/web conferencing technologies (Pocket Camcorder, Skype, Adobe Connect) were used in regional schools in Australia to determine whether the technologies are appropriate for the needs of the university supervisor, trainee teachers and supervising teachers with regard to practicum teaching placements. Findings revealed that Pocket…

Effects of using mobile device-based academic electronic medical records for clinical practicum by undergraduate nursing students: A quasi-experimental study.

PubMed

Choi, Mona; Lee, HyeongSuk; Park, Joon Ho

2018-02-01

The academic electronic medical record (AEMR) system is applied with the expectation that nursing students will be able to attain competence in healthcare decision-making and nursing informatics competencies. However, there is insufficient evidence regarding the advantage of applying mobile devices to clinical practicum. This study aimed to examine the effect of an experiment that introduced a mobile AEMR application for undergraduate nursing students in their practicum. A quasi-experimental design was used. The subjects were 75 third-year nursing students enrolled in clinical practicum and were divided into an experimental (practicum with AEMR) and a control (conventional practicum) group. Nursing informatics competencies, critical thinking disposition, and satisfaction with clinical practicum were measured before and after the clinical practicum for each group. The usability of the AEMR application was also examined for the experimental group after the experiment. After the experiment, the experimental group showed a significant increase in the informatics knowledge domain of nursing informatics competencies in the post-test. The difference in critical thinking between the experimental and control groups was not statistically significant. Regarding satisfaction with the clinical practicum, the experimental group exhibited a significantly higher level of satisfaction in "preparation of a diagnostic test or laboratory test and understanding of the results" and "nursing intervention and documentation" than the control group. Students who participated in the practicum using the AEMR application considered it useful. The AEMR application was an effective educational method for practicing the immediate documentation of students' observations and interventions and was available at the patients' bedsides. To improve critical thinking, it is necessary to apply a variety of approaches when solving clinical problems. Copyright © 2017 Elsevier Ltd. All rights reserved.

Effectiveness of applying flipped learning to clinical nursing practicums for nursing students in Korea: A randomized controlled trial.

PubMed

Kim, Hyun Sook; Kim, Mi Young; Cho, Mi-Kyoung; Jang, Sun Joo

2017-10-01

The purpose of this study was to develop flipped learning models for clinical practicums and compare their effectiveness regarding learner motivation toward learning, satisfaction, and confidence in performing core nursing skills among undergraduate nursing students in Korea. This study was a randomized clinical trial designed to compare the effectiveness of 2 flipped learning models. Data were collected for 3 days from October 21 to 23, 2015 before the clinical practicum was implemented and for 2 weeks from October 26 to December 18, 2015 during the practicum period. The confidence of the students in performing core nursing skills was likely to increase after they engaged in the clinical practicum in both study groups. However, while learner confidence and motivation were not affected by the type of flipped learning, learner satisfaction did differ between the 2 groups. The findings indicate that applying flipped learning allows students to conduct individualized learning with a diversity of clinical cases at their own level of understanding and at their own pace before they participate in real-world practicums. © 2017 John Wiley & Sons Australia, Ltd.

Land Surface Data Assimilation and the Northern Gulf Coast Land/Sea Breeze

NASA Technical Reports Server (NTRS)

Lapenta, William M.; Blackwell, Keith; Suggs, Ron; McNider, Richard T.; Jedlovec, Gary; Kimball, Sytske; Arnold, James E. (Technical Monitor)

2002-01-01

A technique has been developed for assimilating GOES-derived skin temperature tendencies and insolation into the surface energy budget equation of a mesoscale model so that the simulated rate of temperature change closely agrees with the satellite observations. A critical assumption of the technique is that the availability of moisture (either from the soil or vegetation) is the least known term in the model's surface energy budget. Therefore, the simulated latent heat flux, which is a function of surface moisture availability, is adjusted based upon differences between the modeled and satellite observed skin temperature tendencies. An advantage of this technique is that satellite temperature tendencies are assimilated in an energetically consistent manner that avoids energy imbalances and surface stability problems that arise from direct assimilation of surface shelter temperatures. The fact that the rate of change of the satellite skin temperature is used rather than the absolute temperature means that sensor calibration is not as critical. The sea/land breeze is a well-documented mesoscale circulation that affects many coastal areas of the world including the northern Gulf Coast of the United States. The focus of this paper is to examine how the satellite assimilation technique impacts the simulation of a sea breeze circulation observed along the Mississippi/Alabama coast in the spring of 2001. The technique is implemented within the PSU/NCAR MM5 V3-4 and applied on a 4-km domain for this particular application. It is recognized that a 4-km grid spacing is too coarse to explicitly resolve the detailed, mesoscale structure of sea breezes. Nevertheless, the model can forecast certain characteristics of the observed sea breeze including a thermally direct circulation that results from differential low-level heating across the land-sea interface. Our intent is to determine the sensitivity of the circulation to the differential land surface forcing produced via the

Application of Land Surface Data Assimilation to Simulations of Sea Breeze Circulations

NASA Technical Reports Server (NTRS)

Mackaro, Scott; Lapenta, William M.; Blackwell, Keith; Suggs, Ron; McNider, Richard T.; Jedlovec, Gary; Kimball, Sytske

2003-01-01

A technique has been developed for assimilating GOES-derived skin temperature tendencies and insolation into the surface energy budget equation of a mesoscale model so that the simulated rate of temperature change closely agrees with the satellite observations. A critical assumption of the technique is that the availability of moisture (either from the soil or vegetation) is the least known term in the model's surface energy budget. Therefore, the simulated latent heat flux, which is a function of surface moisture availability, is adjusted based upon differences between the modeled and satellite- observed skin temperature tendencies. An advantage of this technique is that satellite temperature tendencies are assimilated in an energetically consistent manner that avoids energy imbalances and surface stability problems that arise from direct assimilation of surface shelter temperatures. The fact that the rate of change of the satellite skin temperature is used rather than the absolute temperature means that sensor calibration is not as critical. The sea/land breeze is a well-documented mesoscale circulation that affects many coastal areas of the world including the northern Gulf Coast of the United States. The focus of this paper is to examine how the satellite assimilation technique impacts the simulation of a sea breeze circulation observed along the Mississippi/Alabama coast in the spring of 2001. The technique is implemented within the PSUNCAR MM5 V3-5 and applied at spatial resolutions of 12- and 4-km. It is recognized that even 4-km grid spacing is too coarse to explicitly resolve the detailed, mesoscale structure of sea breezes. Nevertheless, the model can forecast certain characteristics of the observed sea breeze including a thermally direct circulation that results from differential low-level heating across the land-sea interface. Our intent is to determine the sensitivity of the circulation to the differential land surface forcing produced via the

Nearshore circulation on a sea breeze dominated beach during intense wind events

NASA Astrophysics Data System (ADS)

Torres-Freyermuth, Alec; Puleo, Jack A.; DiCosmo, Nick; Allende-Arandía, Ma. Eugenia; Chardón-Maldonado, Patricia; López, José; Figueroa-Espinoza, Bernardo; de Alegria-Arzaburu, Amaia Ruiz; Figlus, Jens; Roberts Briggs, Tiffany M.; de la Roza, Jacobo; Candela, Julio

2017-12-01

A field experiment was conducted on the northern Yucatan coast from April 1 to April 12, 2014 to investigate the role of intense wind events on coastal circulation from the inner shelf to the swash zone. The study area is characterized by a micro-tidal environment, low-energy wave conditions, and a wide and shallow continental shelf. Furthermore, easterly trade winds, local breezes, and synoptic-scale events, associated with the passage of cold-fronts known as Nortes, are ubiquitous in this region. Currents were measured concurrently at different cross-shore locations during both local and synoptic-scale intense wind events to investigate the influence of different forcing mechanisms (i.e., large-scale currents, winds, tides, and waves) on the nearshore circulation. Field observations revealed that nearshore circulation across the shelf is predominantly alongshore-directed (westward) during intense winds. However, the mechanisms responsible for driving instantaneous spatial and temporal current variability depend on the weather conditions and the across-shelf location. During local strong sea breeze events (W > 10 m s-1 from the NE) occurring during spring tide, westward circulation is controlled by the tides, wind, and waves at the inner-shelf, shallow waters, and inside the surf/swash zone, respectively. The nearshore circulation is relaxed during intense land breeze events (W ≈ 9 m s-1 from the SE) associated with the low atmospheric pressure system that preceded a Norte event. During the Norte event (Wmax≈ 15 m s-1 from the NNW), westward circulation dominated outside the surf zone and was correlated to the Yucatan Current, whereas wave breaking forces eastward currents inside the surf/swash zone. The latter finding implies the existence of large alongshore velocity shear at the offshore edge of the surf zone during the Norte event, which enhances mixing between the surf zone and the inner shelf. These findings suggest that both sea breezes and Nortes play

Mesoscale model response to random, surface-based perturbations — A sea-breeze experiment

NASA Astrophysics Data System (ADS)

Garratt, J. R.; Pielke, R. A.; Miller, W. F.; Lee, T. J.

1990-09-01

The introduction into a mesoscale model of random (in space) variations in roughness length, or random (in space and time) surface perturbations of temperature and friction velocity, produces a measurable, but barely significant, response in the simulated flow dynamics of the lower atmosphere. The perturbations are an attempt to include the effects of sub-grid variability into the ensemble-mean parameterization schemes used in many numerical models. Their magnitude is set in our experiments by appeal to real-world observations of the spatial variations in roughness length and daytime surface temperature over the land on horizontal scales of one to several tens of kilometers. With sea-breeze simulations, comparisons of a number of realizations forced by roughness-length and surface-temperature perturbations with the standard simulation reveal no significant change in ensemble mean statistics, and only small changes in the sea-breeze vertical velocity. Changes in the updraft velocity for individual runs, of up to several cms-1 (compared to a mean of 14 cms-1), are directly the result of prefrontal temperature changes of 0.1 to 0.2K, produced by the random surface forcing. The correlation and magnitude of the changes are entirely consistent with a gravity-current interpretation of the sea breeze.

The influence of the Atlantic Warm Pool on the Florida panhandle sea breeze

USGS Publications Warehouse

Misra, Vasubandhu; Moeller, Lauren; Stefanova, Lydia; Chan, Steven; O'Brien, James J.; Smith, Thomas J.; Plant, Nathaniel

2011-01-01

In this paper we examine the variations of the boreal summer season sea breeze circulation along the Florida panhandle coast from relatively high resolution (10 km) regional climate model integrations. The 23 year climatology (1979–2001) of the multidecadal dynamically downscaled simulations forced by the National Centers for Environmental Prediction–Department of Energy (NCEP-DOE) Reanalysis II at the lateral boundaries verify quite well with the observed climatology. The variations at diurnal and interannual time scales are also well simulated with respect to the observations. We show from composite analyses made from these downscaled simulations that sea breezes in northwestern Florida are associated with changes in the size of the Atlantic Warm Pool (AWP) on interannual time scales. In large AWP years when the North Atlantic Subtropical High becomes weaker and moves further eastward relative to the small AWP years, a large part of the southeast U.S. including Florida comes under the influence of relatively strong anomalous low-level northerly flow and large-scale subsidence consistent with the theory of the Sverdrup balance. This tends to suppress the diurnal convection over the Florida panhandle coast in large AWP years. This study is also an illustration of the benefit of dynamic downscaling in understanding the low-frequency variations of the sea breeze.

Carrying Out Collaborative Action Research in a Practicum

ERIC Educational Resources Information Center

Ho, Belinda

2013-01-01

To help in-service English teachers improve their teaching practices and pupils' learning opportunities through an enquiry-oriented and cooperative approach, the author carried out collaborative action research during a practicum in a teacher education course at a university in Hong Kong. This article describes how the collaborative research…

"It's a Difficult Matter": Historical Perspectives on the Enduring Problem of the Practicum in Teacher Preparation

ERIC Educational Resources Information Center

Vick, Malcolm

2006-01-01

Current reviews of teacher education pay considerable attention to problems associated with the practicum, and often claim to propose major changes in order to improve the quality of new graduates. Many of the problems they address concerning the practicum and its relation to the "theoretical" component of programs are longstanding, and…

Student Responses to an ICT-Based E-Assessment Application for the Teaching Practicum/Teaching Practice MODULE

ERIC Educational Resources Information Center

Davids, M. Noor

2017-01-01

Situated within the context of Initial Teacher Education (ITE) in South Africa, this study introduces the notion of an interactive Teaching Practicum E- Assessment application: e-assessment application for the teaching practicum/Teaching Practice module to replace the current model of assessment. At present students enrolled for an Initial Teacher…

The Complexity of Practicum Assessment in Teacher Education: An Examination of Four New Zealand Case Studies

ERIC Educational Resources Information Center

Aspden, Karyn M.

2017-01-01

Practicum is a key element of initial teacher education (ITE) programmes, designed to support the professional growth of student teachers. Practicum is also a key point of assessment, leading to a determination of the student's professional growth and their readiness to teach and enter the teaching profession. This study sought to understand the…

Student Teachers' Views of Practicums (Teacher Training Placements) in Turkish and English Contexts: A Comparative Study

ERIC Educational Resources Information Center

Busher, Hugh; Gündüz, Müge; Cakmak, Melek; Lawson, Tony

2015-01-01

How student teachers experience their transformation into serving teachers in the liminal social spaces of the school-based practicum (teaching practice) is of key importance to them, their future students and their educators. The practicum is a challenging experience for student teachers, even with help from university and school-based mentors,…

310 Individualized Teacher Practicum. Final Report, 1979-80.

ERIC Educational Resources Information Center

Barabe, Rosemeri, Comp.; And Others

Objectives and program descriptions are presented for the Scottsdale Adult Learning Center (Arizona) which in 1979-80 conducted a number of practicums for adult educators on individualized techniques, Adult Basic Education (ABE), High School Equivalency (GED), and English as a Second Language (ESL). First described is a paid internship program for…

Investigation of the Mesoscale Interaction between the Sea Breeze Circulation and the Sandhills Convection

NASA Astrophysics Data System (ADS)

Sims, Aaron P.

In the Carolinas of the United States, there are two key land-surface features over which convective precipitation often forms during the summer months. These geomorphic features are the Sandhills and coastline. Along the coastline, sea-breeze circulations regularly form and are known to initiate convection. The Sandhills is a transitional zone of sandy soil surrounded by mixture of soils that include clay and loam. It extends through the central part of the Carolinas and into Georgia and is also the origin of convective storms. The two geographical features, the coastline and the Sandhills, are in regional proximity of each other and the resultant sea-breeze front and the Sandhills convection interact during summer. During this research, the investigation of the mechanism of interaction between these two features has led to the discovery of the Sandhills front, a shallow outflow density current that develops from deep convection over the Sandhills and propagates eastward toward the coast. The convergence of the Sandhills front and the sea-breeze front initiates and enhances convection between the Sandhills and the coastline. Observations during the month of June for the period 2004 to 2015 are used to evaluate the interaction between these two phenomena. On average, these interactions occur on approximately 24% of all days in June and on 36% of all days in June when synoptic scale systems are absent. Thus, the interactions between the sea-breeze and the Sandhills circulations do contribute to the precipitation in this region. Background wind speeds and directions influence the location and the strength of convection associated with this interaction. Onshore, offshore, and southwesterly flow classifications each present different strengths and locations of the interactions. Light winds ( 3 m s-1 to 6 m s-1 ) also influence the interactions differently. Observations indicate that moderate southwesterly flow has the highest total average and total maximum

Evaluating Creative Thinking of Rn-Bsn Students in the Course of Clinical Case Study and Practicum

ERIC Educational Resources Information Center

Ku, Ya-Lie

2015-01-01

This case study evaluated creative thinking of RN-BSN students in the course of clinical case study and practicum. Study design used quantitative and qualitative evaluations of creative thinking of RN-BSN students by triangulation method in the course of clinical case study and practicum. Sixty RN-BSN students self-perceived the changing levels of…

Impacts of the land-lake breeze of the Volta reservoir on the diurnal cycle of cloudiness and precipitation

NASA Astrophysics Data System (ADS)

Buchholz, Marcel; Fink, Andreas H.; Knippertz, Peter; Yorke, Charles

2017-04-01

Lake Volta in Ghana is the artificial lake on Earth with the largest surface area (8502 km2). It has been constructed in the early 1960s, with the lake being filled around 1966. Land-lake breezes and their effects on the diurnal cycle of local wind systems, cloudiness, and precipitation have been studied for several tropical lakes, among which studies on the effects of Lake Victoria in East Africa are one of the most perceived ones. To date, no studies on the strengths and effects of the land-lake breeze of the Volta reservoir are known to the authors. Using surface station data, a variety of satellite data on clouds and precipitation, and a convection-resolving regional model, the land-lake breeze and its impacts were studied for Lake Volta between 1998 and 2015. The observational data sets confirm a significant land-lake circulation. The only manned weather station operated by the Ghana Meteorological Service that is situated at the lake is Kete Krachi. Hourly observations for 2006 and 2014 show on several days a clearing of skies in the afternoon associated with a shift in the surface winds from southwest to southeast, the latter potentially indicating a lake breeze effect. Cloud occurrence frequency derived from the CLARA-A2, MODIS, and CLAAS2 cloud masks and the cloud physical properties from CLAAS2 clearly show the development of clouds at the lake breeze front in the course of the morning and around mid-day. This effect is most pronounced in March when also the difference between the surface temperatures of the lake and the desiccated land surface is strongest. During the peak of the wet season in July, the lake breeze cloudiness is masked by a high background cloudiness and likely also weaker due to the strong southwesterly monsoon flow that tends to weaken the land-lake circulation. However, the precipitation signal was found to be strongest in July, most probably due to the fact that in boreal fall, winter and spring, the lake breeze cloudiness often

Missing Voices in the Study of the Practicum

ERIC Educational Resources Information Center

Clift, Renée T.

2017-01-01

Author Renee T. Clift provides this commentary on the articles presented in this issue of "Studying Teacher Education." Clift begins by writing that while this issue of the journal gives voice to teacher educators who are seeking to better understand and improve their work with teacher candidates during the practicum experience, she…

Content Analysis of the Practicum Course in the Master of Science in Educational Leadership/Administration Program

ERIC Educational Resources Information Center

Norman, Scott W.

2013-01-01

In this study, I explored the overall efficacy of the Master of Science in Educational Leadership/ Administration (MSEL/A) program at Florida State University (FSU), by taking a closer look at the introductory course, Practicum in Educational Leadership (the Practicum), as well as the final assessment, the student e-portfolio. The MSEL/A at FSU is…

A study of the Merritt Island, Florida sea breeze flow regimes and their effect on surface heat and moisture fluxes

NASA Technical Reports Server (NTRS)

Rubes, M. T.; Cooper, H. J.; Smith, E. A.

1993-01-01

Data collected during the Convective and Precipitation/Electrification Experiment were analyzed as part of an investigation of the sea breeze in the vicinity of Merritt Island, Florida. Analysis of near-surface divergence fields shows that the classical 24-hour oscillation in divergence over the island due to the direct sea breeze circulation is frequently disrupted and exhibits two distinct modes: the classical sea breeze pattern and deviations from that pattern. A comparison of clear day surface energy fluxes with fluxes on other days indicates that changes in magnitudes were dominated by the presence or absence of clouds. Non-classical sea breeze days tended to lose more available energy in the morning than classical sea breeze days due to earlier development of small cumulus over the island. A composite storm of surface winds, surface energy fluxes, rainfall, and satellite visible data was constructed. A spectral transmittance over the visible wavelengths for the cloud cover resulting from the composite storm was calculated. It is shown that pre-storm transmittances of 0.8 fall to values near 0.1 as the downdraft moves directly over the site. It is also found that under post-composite storm conditions of continuous clear sky days, 3.5 days are required to evaporate back into the atmosphere the latent heat energy lost to the surface by rainfall.

The influence of the Atlantic Warm Pool on the Florida panhandle sea breeze

USGS Publications Warehouse

Misra, V.; Moeller, L.; Stefanova, L.; Chan, S.; O'Brien, J. J.; Smith, T.J.; Plant, N.

2011-01-01

In this paper we examine the variations of the boreal summer season sea breeze circulation along the Florida panhandle coast from relatively high resolution (10 km) regional climate model integrations. The 23 year climatology (1979-2001) of the multidecadal dynamically downscaled simulations forced by the National Centers for Environmental Prediction-Department of Energy (NCEP-DOE) Reanalysis II at the lateral boundaries verify quite well with the observed climatology. The variations at diurnal and interannual time scales are also well simulated with respect to the observations. We show from composite analyses made from these downscaled simulations that sea breezes in northwestern Florida are associated with changes in the size of the Atlantic Warm Pool (AWP) on interannual time scales. In large AWP years when the North Atlantic Subtropical High becomes weaker and moves further eastward relative to the small AWP years, a large part of the southeast U.S. including Florida comes under the influence of relatively strong anomalous low-level northerly flow and large-scale subsidence consistent with the theory of the Sverdrup balance. This tends to suppress the diurnal convection over the Florida panhandle coast in large AWP years. This study is also an illustration of the benefit of dynamic downscaling in understanding the low-frequency variations of the sea breeze. Copyright 2011 by the American Geophysical Union.

The Global Education Practicum: Perspectives from Accompanying Academics

ERIC Educational Resources Information Center

Lang, Catherine; Cacciattolo, Marcelle; Kidman, Gillian

2017-01-01

The benefits of international education experiences for students are well documented. The effect on the individual of international experiences has been researched and theorised by authors for at least the last 20 years. In this paper the experiences of three academics who accompanied pre-service teachers on a 3 week international practicum are…

Evaluating a Practicum for Gifted Education Graduate Students

ERIC Educational Resources Information Center

Wood, Betty K.; Kittler-Hunter, Karen; Robinson, Ann E.; Wood, Sarah C.

2005-01-01

Each year for the past 25 years, the Center for Gifted Education at the University of Arkansas at Little Rock conducts a three-week summer enrichment program for gifted and talented students entitled Summer Laureate/University for Youth. The program was developed to provide a practicum experience for teachers seeking either licensure or a master's…

Essential Characteristics of EFL Practicum Supervisors from Their Perspective

ERIC Educational Resources Information Center

Dakhiel, Maysoon A.

2017-01-01

The present study aims to identify the essential characteristics required for the EFL practicum supervisors from their perspective. The questionnaire validity and reliability was tested through application to a sample of (7) supervisors. Then the questionnaire was distributed to the participants, which consisted of (20) EFL supervisors for the…

Using the Project Approach in a Teacher Education Practicum

ERIC Educational Resources Information Center

Vasconcelos, Teresa

2007-01-01

This paper describes the early childhood teacher training program and the role of the Project Approach in the final practicum for student teachers in the Lisbon School of Education, Portugal. Student teachers, cooperating teachers, university supervisors, and instructors of teaching methods worked together to involve young children in interesting…

Problematizing the Practicum to Integrate Practical Knowledge

NASA Astrophysics Data System (ADS)

Melville, Wayne; Campbell, Todd; Fazio, Xavier; Stefanile, Antonio; Tkaczyk, Nicholas

2014-10-01

This article examines the influence of a practicum teaching experience on two pre-service science teachers. The research is focused on examining a practicum in a secondary science department that actively promotes the teaching and learning of science as inquiry. We investigated the process through which the pre-service science teachers integrated their practical knowledge, and examined this in the context of the quantified reformed instruction they enacted. Using a mixed methods design, we have quantified these pre-service science teachers' practice using the Reformed Teaching Observation Protocol (Piburn et al. 2000), in concert with a narrative methodology drawn from in-depth interviews. Our analysis of the data indicates two important conclusions. The first is the importance of a consistently reformed image of science education being presented and practiced by both science teacher educators and cooperating teachers. The second is the recognition that a consistently reformed image may not be sufficient, of itself, to challenge pre-service teachers' views of science education. Pre-service teachers appear to be heavily influenced by their biographies and own science education. Consequently, it appears the extent to which a pre-service teacher identifies problems of teaching and learning, and then works toward possible resolution, influences their progress in shaping reformed views of science education.

Land Breeze and Thermals: A Scale Threshold to Distinguish Their Effects

Treesearch

Yongqiang Liu

2005-01-01

Land breeze is a type of mesoscale circulation developed due to thermal forcing over a heterogeneous landscape. It can contribute to atmospheric dynamic and hydrologic processes through affecting heat and water fluxes on the land-atmosphere interface and generating shallow convective precipitation. If the scale of the landscape heterogeneity is smaller than a certain...

Aboriginal Post-Interns' Views of Their Rural Teaching-Practicum

ERIC Educational Resources Information Center

Gerard, Jessi; Lapointe, Joshua; Ralph, Edwin; Walker, Keith

2013-01-01

In this article, two indigenous post-interns, who completed their 16-week extended-teaching practicum sessions in rural schools in one Western Canadian province, assess their school-based internship experiences. They summarize their perspectives in three areas: 1) the elements they perceived as positive during the internship, 2) the challenging…

In Search of Ways to Improve Practicum Learning: Self-Study of the Teacher Educator/Researcher as Responsive Listener

ERIC Educational Resources Information Center

Martin, Andrea K.

2017-01-01

Teacher education programs that appear to be more successful work to thread practicum experiences and on-campus courses with an eye to achieving overall program coherence. As part of a funded research project centred on understanding how teacher candidates perceive quality in their practicum experiences and, by extension, in their professional…

Supervising the Extended Practicum: A Contextual Approach. Monograph No. 4.

ERIC Educational Resources Information Center

Ralph, Edwin G.

Conflicts or disagreements between student teachers and university supervisors in the Extended Practicum program, College of Education, University of Saskatchewan, are often attributed to factors such as "personality clash," laziness, stubbornness, authoritarianism, prejudice, stereotyping, dogmatism, or malice. In reality, many of these…

Learning to Learn about the Practicum: A Self-Study of Learning to Support Student Learning in the Field

ERIC Educational Resources Information Center

Thomas, Lynn

2017-01-01

This study explores student teacher learning on the practicum from the perspective of supervisors, associate teachers, professors in pre-service teacher education programs and the students themselves. Self-study became a means by which I came to better understand the phenomenon of practicum as a whole, the constraints and opportunities, the where…

Chinese Student Teachers' Perspectives on Becoming a Teacher in the Practicum: Emotional and Ethical Dimensions of Identity Shaping

ERIC Educational Resources Information Center

Zhu, Gang

2017-01-01

This research examines the emotional and ethical dimensions of identity shaping in student teachers' teaching practicum. By interviewing seven Chinese student teachers who had just finished their student teaching practice, the research examines the participants' emotional experiences and the ethical dilemmas they encountered in their practicum.…

Evaluation of the atmospheric model WRF on the Qatar peninsula for a converging sea-breeze event

NASA Astrophysics Data System (ADS)

Balan Sobhana, Sandeepan; Nayak, Sashikant; Panchang, Vijay

2016-04-01

Qatar, a narrow peninsula covering an area of 11437 sq km, extends northwards into the Arabian Gulf for about 160km and has a maximum width of 88km. The convex shape of the coast-line and narrowness of the peninsula results in the Qatar region experiencing complex wind patterns. The geometry is favorable for formation of the land-sea breeze from both coastal sides of the peninsula. This can lead to the development of sea breeze convergence zones in the middle of the country. Although circulations arising from diurnal thermal contrast of land and water are amongst most intensively studied meteorological phenomena, there is no reported study for the Qatar peninsula and very few studies are reported for the Arabian Gulf region as whole. It is necessary to characterize the wind field for applications such as assessing air pollution, renewable energy etc. A non-hydrostatic mesoscale model, Weather Research and Forecast (WRF) with a nested high resolution grid permits the investigation of such fine scale phenomena. Data from eighteen land based Automated Weather Stations (AWS) and two offshore buoys deployed and maintained by the Qatar Meteorological Department were analyzed. Based on the analysis a clear case of sea breeze convergence were seen on 18 September 2015. Model simulations were used to investigate the synoptic conditions associated with the formation of this event. The season is characterized by week ambient north westerly wind over the Arabian Gulf. The WRF model performance is validated using observed in-situ data. Model simulations show that vertical extent of sea breeze cell was up to 1 km and the converging sea breeze regions were characterized with high vertical velocities. The WRF simulation also revealed that with high resolution, the model is capable of reproducing the fine scale patterns accurately. The error of predictions in the inner domain (highest resolution) are found to be relatively lower than coarse resolution domain. The maximum wind speed

The daily events and emotions of master's-level family therapy trainees in off-campus practicum settings.

PubMed

Edwards, Todd M; Patterson, Jo Ellen

2012-10-01

The Day Reconstruction Method (DRM) was used to assess the daily events and emotions of one program's master's-level family therapy trainees in off-campus practicum settings. This study examines the DRM reports of 35 family therapy trainees in the second year of their master's program in marriage and family therapy. Four themes emerged from the results: (i) Personal contact with peers-in-training engenders the most positive emotions during practicum; (ii) Trainees experience more positive emotions during therapy with families and couples in comparison with therapy with individuals; (iii) Positive affect increases over the course of a student's practicum year; and (iv) Trainees experience less positive affect in individual supervision in comparison with most other training activities. Flow theory offers guidance for supervisors helping trainees face developmental challenges of clinical training. © 2012 American Association for Marriage and Family Therapy.

The properties of coke breeze briquettes produced by ram briquetting

NASA Astrophysics Data System (ADS)

Loginov, Yu. N.; Babailov, N. A.; Polyansky, L. I.

2017-12-01

The paper reports on the results of briquetting coke breeze with a binder in a closed cylindrical press-die. Liquid glass is used as a binder. Approximating curves for the "compaction ratio vs. compaction pressure" dependences are plotted from experimental data. The mechanical properties of the briquettes are determined, namely, drop damage resistance and breaking stress. The results are presented as approximating dependences in the form of a power function.

Taking Risks with a Growth Mindset: Long-Term Influence of an Elementary Pre-Service after School Science Practicum

ERIC Educational Resources Information Center

Cartwright, T. J.; Hallar, B.

2018-01-01

In this study, we present the long-term influence of an after school science practicum associated with an elementary science methods course. The practicum or field experience could be considered a community-based service learning programme as it is situated both within and for the community. Study participants included eight third- and fifth-grade…

Understanding Student-Teachers' Performances within an Inquiry-Based Practicum

ERIC Educational Resources Information Center

Méndez Rivera, Pilar; Pérez Gómez, Francisco

2017-01-01

The role of an inquiry-based practicum in the education of future teachers has been identified as a key component to foster student-teachers' abilities to face problems, try to solve them, work on doubts and produce situated and valuable learning from their own practices (Cochran-Smith & Little, 2001; Beck, 2001). The interaction between…

Supervising an International Teaching Practicum: Building Partnerships in Postcolonial Contexts

ERIC Educational Resources Information Center

Major, Jae; Santoro, Ninetta

2016-01-01

Teaching practicum experiences, including those in international contexts, are based on partnerships between institutions and host schools, and the partnership between the pre-service teacher, the cooperating teacher and the university supervisor. This article explores the relationship between pre-service teachers and cooperating teachers in an…

Identification of the Sea-Land Breeze Event and Influence to the Convective Activities on the Coast of Deli Serdang

NASA Astrophysics Data System (ADS)

Saragih, I. J. A.; Putra, A. W.; Nugraheni, I. R.; Rinaldy, N.; Yonas, B. W.

2017-12-01

Located close to the sea indicates that there are influences of the sea-land breeze circulation on the weather condition in Deli Serdang. The purpose of this study is to simulate sea-land breeze occurrence and its influence on the convective activities in Deli Serdang. The research area covers the area of Deli Serdang Regency and the surrounding ocean region in the coordinates 02°57‧-03°16‧N & 98°33‧-99°27‧E where Kualanamu Meteorological Station is the centre of the research area at coordinate 03°34‧N & 98°44‧E and the elevation about 27MAMSL. The research time is a day with the highest rainfall in the highest peak rainy month. The raw data consist of the Himawari-8 satellite image from BMKG, FNL (Final Analysis) data from http://rda.ucar.edu, and meteorological observation data from Kualanamu Meteorology Station. This study indicates that WRF-ARW can simulate the sea-land breeze occurrence on the coast of Deli Serdang well. The existence of the convective index cover in the convergence area proves the sea-land breeze occurred in the coast of Deli Serdang can form the convergence area as the interacted result with the wind from other directions that support convective activities.

Finding the Shoe that Fits: Experiential Approaches for First Practicum

ERIC Educational Resources Information Center

O'Connell, William P.; Smith, Jacqueline

2005-01-01

Graduate counselling students in the first semester of practicum are challenged to learn the basic active listening sequence while simultaneously learning to engage in the supervision process. Students struggle with confusion and self-doubt as they attempt to develop self-efficacy as a professional counsellor. Adult learning theory and…

Counselor Effectiveness As A Function of Varied Practicum Training Techniques.

ERIC Educational Resources Information Center

Snyder, John F.; And Others

This study investigated the differential effects of various training techniques on the counselor effectiveness of beginning practicum students. It was hypothesized that there would be significant differences between the subjects pre- and post-test scores on both the Affective Sensitivity Scale (ASS) and on the Counselor Verbal Response Scale…

Use of mobile devices in nursing student-nurse teacher cooperation during the clinical practicum: an integrative review.

PubMed

Strandell-Laine, Camilla; Stolt, Minna; Leino-Kilpi, Helena; Saarikoski, Mikko

2015-03-01

To identify and appraise study findings on the use of mobile devices, in particular for what purposes and how, in nursing student-nurse teacher cooperation during the clinical practicum. A systematic literature search was conducted using the PubMed/Medline, CINAHL, PsycINFO and ERIC for primary empirical studies published in English. An integrative literature review was undertaken. Quality appraisal of the included studies was conducted using design-specific standardized checklists. Studies were thematically analyzed. Based on the inclusion and exclusion criteria, eleven studies were included in the review. Weaknesses in designs, samples, questionnaires and results, compromised comparison and/or generalization of the findings of the studies. Three main themes were identified: (1) features of mobile devices (2) utility of mobile devices and (3) barriers to the use of mobile devices. Problems of connectivity were the main challenges reported in the use of mobile devices. Participants used mobile devices primarily as reference tools, but less frequently as tools for reflection, assessment or cooperation during the clinical practicum. Interest in mobile device use during the clinical practicum was reported, but training and ongoing support are needed. As only a small number of eligible primary empirical studies were found, it is not possible to draw firm conclusions on the results. In the future, rigorous primary empirical studies are needed to explore the potential of mobile devices in providing a supplementary pedagogical method in nursing student-nurse teacher cooperation during the clinical practicum. Robust study designs, including experimental ones, are clearly needed to assess the effectiveness of mobile devices in nursing student-nurse teacher cooperation during the clinical practicum. Copyright © 2014 Elsevier Ltd. All rights reserved.

Practicum Experiences as Sources of Pre-Service Teachers' Self-Efficacy

ERIC Educational Resources Information Center

Martins, Maria; Costa, João; Onofre, Marcos

2015-01-01

This study examines physical education pre-service teachers' (PTs) self-efficacy and practicum experiences as self-efficacy sources through a mixed-method approach. For the quantitative phase, a self-efficacy questionnaire was applied to 141 PTs. Results showed a stronger self-efficacy in the relationship with students and discipline promotion.…

Practicum for Simulated Methods in Office Occupation Education. Final Report.

ERIC Educational Resources Information Center

Hanson, Garth A.

Thirty-six participants and four observers representing 34 states attended the practicum at the Utah State University campus in Logan, July 8-19, 1968. The purpose was to provide high school business teachers with practical knowledge, experience, and materials for designing and operating simulated business offices in their classrooms. The…

Web Conferencing of Pre-Service Teachers' Practicum in Remote Schools

ERIC Educational Resources Information Center

Gronn, Donna; Romeo, Geoff; McNamara, Sue; Teo, Yiong Hwee

2013-01-01

The purpose of this study was to field-test several conferencing technologies in regional schools to determine whether the technologies are appropriate for the needs of the university supervisor, trainee teachers and supervising teachers in practicum placements. The study also explored the potential of technology for other related purposes. Four…

Explicating Practicum Program Theory: A Case Example in Human Ecology

ERIC Educational Resources Information Center

Chandler, Kathryn M. M.; Williamson, Deanna L.

2013-01-01

This study explicated the theory underpinning the Human Ecology Practicum Program offered in the Department of Human Ecology at the University of Alberta. The program has operated for 40 years but never been formally evaluated. Using a document analysis, focus group and individual interviews, and a stakeholder working group, we explored…

The Practicum Course Model: Embracing the Museum-University Culture Clash

ERIC Educational Resources Information Center

Kingsley, Jennifer P.

2016-01-01

Museums and universities have natural connections. Yet with few exceptions, collaborations between them segregate each partner to its traditional sphere of activity. This article presents a practicum course model that blurs and overlaps the distinctive roles of the museum and university in productive and mutually beneficial ways. In particular,…

The Impact of Facebook in Teaching Practicum: Teacher Trainees' Perspectives

ERIC Educational Resources Information Center

Goktalay, Sehnaz Baltaci

2015-01-01

Prompt feedback is one of the critical components of teacher education programs. To reap the greatest benefit from the teaching practicum process, the quality of feedback as well as its implementation by stakeholders, supervisors, cooperating teachers, and teacher trainees, takes on great importance. The purpose of this study is to examine how Web…

Measuring Practicum Student Teachers' Reflectivity: The Reflective Pedagogical Thinking Scale

ERIC Educational Resources Information Center

Seng, Toh Wah

2004-01-01

The purpose of the original study was to investigate practicum student teachers' reflectivity. This paper describes the use of a revised version of the Reflective Pedagogical Thinking Scale (Sparks-Langer, et al., 1990) to measure reflectivity. The original scale was used by the developers to assess reflectivity through a structured interview. The…

Pre-Service English Teachers' Voices about the Teaching Practicum

ERIC Educational Resources Information Center

Castañeda-Trujillo, Jairo Enrique; Aguirre-Hernández, Ana Jackelin

2018-01-01

This paper shows the results of a pedagogical experience with a group of pre-service English teachers during their first semester of teaching practicum. The data were collected by means of reflection papers written by them, and then the resulting papers were analyzed under the principles of codification of grounded theory. The results show that…

Using iPad2 for a Graduate Practicum Course

ERIC Educational Resources Information Center

Sachs, Lindsey; Bull, Prince Hycy

2012-01-01

iPads and iPhones continue to impact academia, but the iPad2 provides features that could enhance teacher education programs. This paper addresses how eight graduate students and a faculty used iPad2 to support a graduate practicum course. Participants were asked to report how they used their iPad2 each week in the form of a written log and…

An evidence based approach to undergraduate physical assessment practicum course development.

PubMed

Anderson, Brenda; Nix, Elizabeth; Norman, Bilinda; McPike, H Dawn

2014-05-01

Physical assessment is an important component of professional nursing practice. New nurse graduates experience difficulty transitioning the traditional head to toe physical assessment into real world nursing practice. This study was conducted to provide current data concerning physical assessment competencies utilized consistently by registered nurses. This quantitative study used a 126 item survey mailed to 900 Registered Nurses. Participants used a Likert-type scale to report frequency of use for physical assessment competencies. Thirty seven competencies were determined to be essential components of the physical assessment, 18 were determined supplemental, and 71 were determined to be non-essential. Transition of the new graduate nurse into professional practice can be enhanced by focusing content in physical assessment practicum courses on the essential competencies of physical assessment. Faculty for the university has analyzed data from this study to support evidence based changes to the undergraduate nursing program physical assessment practicum course. Copyright © 2013 Elsevier Ltd. All rights reserved.

Stretch and Studio Composition Practicum: Creating a Culture of Support and Success for Developing Writers at a Hispanic-Serving Institution

ERIC Educational Resources Information Center

Elder, Cristyn L.; Davila, Bethany

2017-01-01

This course design describes a 3-credit, two-week intensive Stretch and Studio Practicum course at the University of New Mexico (UNM). Because the Stretch and Studio composition curriculum is designed to help students who may be at greater risk of not succeeding, instructors are required to complete the practicum before teaching in the program.…

Results of a Practicum Offering Teaching-Focused Graduate Student Professional Development

ERIC Educational Resources Information Center

Richards-Babb, Michelle; Penn, John H.; Withers, Michelle

2014-01-01

Providing chemistry graduate students with opportunities to learn about evidence-based teaching and to practice teaching skills in a mentored environment is crucial to their professional development. Herein is described the model for a graduate-level teaching practicum course specifically focused on the chemistry discipline. This course addressed…

Unfolding Case-Based Practicum Curriculum Infusing Crisis, Trauma, and Disaster Preparation

ERIC Educational Resources Information Center

Greene, Catie A.; Williams, Amy E.; Harris, Pamela N.; Travis, Sterling P.; Kim, Sharon Y.

2016-01-01

The authors evaluated an unfolding case-based approach to a practicum in counseling course infusing crisis, trauma, and disaster preparation for changes in students' crisis self-efficacy across a semester. The course, informed by constructivist-developmental pedagogy and centered on the unfolding case, resulted in significant increases in…

Effectiveness of a mobile cooperation intervention during the clinical practicum of nursing students: a parallel group randomized controlled trial protocol.

PubMed

Strandell-Laine, Camilla; Saarikoski, Mikko; Löyttyniemi, Eliisa; Salminen, Leena; Suomi, Reima; Leino-Kilpi, Helena

2017-06-01

The aim of this study was to describe a study protocol for a study evaluating the effectiveness of a mobile cooperation intervention to improve students' competence level, self-efficacy in clinical performance and satisfaction with the clinical learning environment. Nursing student-nurse teacher cooperation during the clinical practicum has a vital role in promoting the learning of students. Despite an increasing interest in using mobile technologies to improve the clinical practicum of students, there is limited robust evidence regarding their effectiveness. A multicentre, parallel group, randomized, controlled, pragmatic, superiority trial. Second-year pre-registration nursing students who are beginning a clinical practicum will be recruited from one university of applied sciences. Eligible students will be randomly allocated to either a control group (engaging in standard cooperation) or an intervention group (engaging in mobile cooperation) for the 5-week the clinical practicum. The complex mobile cooperation intervention comprises of a mobile application-assisted, nursing student-nurse teacher cooperation and a training in the functions of the mobile application. The primary outcome is competence. The secondary outcomes include self-efficacy in clinical performance and satisfaction with the clinical learning environment. Moreover, a process evaluation will be undertaken. The ethical approval for this study was obtained in December 2014 and the study received funding in 2015. The results of this study will provide robust evidence on mobile cooperation during the clinical practicum, a research topic that has not been consistently studied to date. © 2016 John Wiley & Sons Ltd.

The Art of Teaching and Learning in the Practicum: The Pedagogical Perceptions of Bilingual Cooperating Teachers in an On-Site Block Program

ERIC Educational Resources Information Center

Valverde-Wheaton, Alicia

2011-01-01

This study will be presented to university education programs, Professional Development Schools, cooperating teachers, preservice teachers, and administrators who are part of the practicum experience. This study concentrated on looking at the perceptions of cooperating teachers about the practicum in preparing preservice teachers to meet the needs…

Pre-Service Primary Teachers Negotiating Physical Education Identities during the Practicum

ERIC Educational Resources Information Center

Fletcher, Tim; Kosnik, Clare

2016-01-01

This research examined the ways in which pre-service primary teachers' experiences of physical education during the practicum influenced the development of their identities as teachers of physical education. Guided by a social constructivist view of identity, semi-structured interviews were conducted with 10 pre-service teachers over one academic…

On the use of GPS tomography to investigate water vapor variability during a Mistral/sea breeze event in southeastern France

NASA Astrophysics Data System (ADS)

Bastin, Sophie; Champollion, Cédric; Bock, Olivier; Drobinski, Philippe; Masson, Frédéric

2005-03-01

Global Positioning System (GPS) tomography analyses of water vapor, complemented by high-resolution numerical simulations are used to investigate a Mistral/sea breeze event in the region of Marseille, France, during the ESCOMPTE experiment. This is the first time GPS tomography has been used to validate the three-dimensional water vapor concentration from numerical simulation, and to analyze a small-scale meteorological event. The high spatial and temporal resolution of GPS analyses provides a unique insight into the evolution of the vertical and horizontal distribution of water vapor during the Mistral/sea-breeze transition.

A Proposal for Methodology for Negotiation Practicum with Effective Use of ICT: A Technology Enhanced Course for Communication for Trust Building

ERIC Educational Resources Information Center

Yamamoto, Tosh; Tagami, Masanori; Nakazawa, Minoru

2012-01-01

This paper purports to demonstrate a problem solving case in the course of the development of methodology, in which the quality of the negotiation practicum is maintained or raised without sacrificing the class contact hours for the lessons for reading comprehension skills, on which the essence of negotiation practicum is solely based. In this…

Learning and Teaching Positive Guidance Skills: Lessons from Early Childhood Practicum Students

ERIC Educational Resources Information Center

McFarland, Laura; Saunders, Rachel; Allen, Sydnye

2008-01-01

Empirical studies of early childhood educators' experiences with learning and implementing positive guidance skills are absent from the extant literature. This study explored this topic with 63 junior and senior level university students who were involved in concurrent instructional lecture and practicum experiences. Participants defined…

The John Milner Nutrition and Cancer Prevention Research Practicum | Division of Cancer Prevention

Cancer.gov

Attendee Testimonial Plenty of Food for Thought Served Up at the John Milner Nutrition and Cancer Prevention Research Practicum by Julia Tobacyk Media Folder: research_groupView the Testimonial (PDF, 790 KB) Date: March 12-16, 2018 |

Evaluation of weather research and forecasting model parameterizations under sea-breeze conditions in a North Sea coastal environment

NASA Astrophysics Data System (ADS)

Salvador, Nadir; Reis, Neyval Costa; Santos, Jane Meri; Albuquerque, Taciana Toledo de Almeida; Loriato, Ayres Geraldo; Delbarre, Hervé; Augustin, Patrick; Sokolov, Anton; Moreira, Davidson Martins

2016-12-01

Three atmospheric boundary layer (ABL) schemes and two land surface models that are used in the Weather Research and Forecasting (WRF) model, version 3.4.1, were evaluated with numerical simulations by using data from the north coast of France (Dunkerque). The ABL schemes YSU (Yonsei University), ACM2 (Asymmetric Convective Model version 2), and MYJ (Mellor-Yamada-Janjic) were combined with two land surface models, Noah and RUC (Rapid Update Cycle), in order to determine the performances under sea-breeze conditions. Particular attention is given in the determination of the thermal internal boundary layer (TIBL), which is very important in air pollution scenarios. The other physics parameterizations used in the model were consistent for all simulations. The predictions of the sea-breeze dynamics output from the WRF model were compared with observations taken from sonic detection and ranging, light detection and ranging systems and a meteorological surface station to verify that the model had reasonable accuracy in predicting the behavior of local circulations. The temporal comparisons of the vertical and horizontal wind speeds and wind directions predicted by the WRF model showed that all runs detected the passage of the sea-breeze front. However, except for the combination of MYJ and Noah, all runs had a time delay compared with the frontal passage measured by the instruments. The proposed study shows that the synoptic wind attenuated the intensity and penetration of the sea breeze. This provided changes in the vertical mixing in a short period of time and on soil temperature that could not be detected by the WRF model simulations with the computational grid used. Additionally, among the tested schemes, the combination of the localclosure MYJ scheme with the land surface Noah scheme was able to produce the most accurate ABL height compared with observations, and it was also able to capture the TIBL.

Analysis of Delayed Sea Breeze Onset for Fort Ord Prescribed Burning Operations

DTIC Science & Technology

2015-12-01

Gahmberg et al. (2009) provided additional detail to the synoptic flow through the Coriolis effect . All directions are as seen from the sea with...ambient flows left of the offshore direction providing the strongest opposing winds as Coriolis effects provide additional support in the offshore...support the development of the sea breeze due to Coriolis effects , the mesoscale flow at the surface is quite different. The 1600 UTC through 1900

Making the Grade: Describing Inherent Requirements for the Initial Teacher Education Practicum

ERIC Educational Resources Information Center

Sharplin, Elaine; Peden, Sanna; Marais, Ida

2016-01-01

This study explores the development, description, and illustration of inherent requirement (IR) statements to make explicit the requirements for performance on an initial teacher education (ITE) practicum. Through consultative group processes with stakeholders involved in ITE, seven IR domains were identified. From interviews with academics,…

The Epistemography of an Urban and Regional Planning Practicum: Appropriation in the Face of Resistance. WCER Working Paper No. 2010-8

ERIC Educational Resources Information Center

Bagley, Elizabeth

2010-01-01

In this paper, the author describes an ethnographic study of a graduate-level practicum at a large Midwestern university in order to examine one of the ways urban planners develop expertise. The graduate students in the practicum were guided in the production of a site plan for a developing area by a planner with 34 years of planning experience.…

Dogmatism, Locus of Control, Perceived Counselor Self-Efficacy, and the Theoretical Orientation of Students in a Master's Level Counseling Practicum

ERIC Educational Resources Information Center

Benesh, Andrew Christopher

2017-01-01

Purpose: The purpose of this study was to fill a gap in the literature by examining the relationship between dogmatism, locus of control, counselor self-efficacy, and counselor theoretical orientation in a sample of master's level practicum students. Method: A total of 45 master's practicum students completed a series of four instruments, the DOG…

Assessing the Impact of Sequencing Practicums for Welding in Agricultural Mechanics

ERIC Educational Resources Information Center

Rose, Malcolm; Pate, Michael L.; Lawver, Rebecca G.; Warnick, Brian K.; Dai, Xin

2015-01-01

This study examined the impact of sequencing practicums for welding on students' ability to perform a 1F (flat position-fillet lap joint) weld on low-carbon steel. Participants were randomly assigned a specific practice sequence of welding for using gas metal arc welding (GMAW) and shielded metal arc welding (SMAW). A total of 71 participants…

Positioning Theory: Kinesiology Students' Experiences Teaching in an Adapted Aquatics Practicum

ERIC Educational Resources Information Center

Sato, Takahiro; Haegele, Justin

2017-01-01

The purpose of this study was to describe and explain undergraduate students' positions of teaching and assisting students with disabilities during adapted aquatics practicum experiences. The participants were eight kinesiology students who enrolled in an introductory adapted physical education (APE) course at a public university in the Midwest…

Applied Research Consultants (ARC): A Vertical Practicum Model of Training Applied Research

ERIC Educational Resources Information Center

Nadler, Joel T.; Cundiff, Nicole L.

2009-01-01

The demand for highly trained evaluation consultants is increasing. Furthermore, the gap between job seekers' evaluation competencies and job recruiters' expectations suggests a need for providing practical training experiences. A model using a vertical practicum (advanced students assisting in the training of newer students) is suggested as an…

The use of physics practicum to train science process skills and its effect on scientific attitude of vocational high school students

NASA Astrophysics Data System (ADS)

Wiwin, E.; Kustijono, R.

2018-03-01

The purpose of the study is to describe the use of Physics practicum to train the science process skills and its effect on the scientific attitudes of the vocational high school students. The components of science process skills are: observing, classifying, inferring, predicting, and communicating. The established scientific attitudes are: curiosity, honesty, collaboration, responsibility, and open-mindedness. This is an experimental research with the one-shot case study design. The subjects are 30 Multimedia Program students of SMK Negeri 12 Surabaya. The data collection techniques used are observation and performance tests. The score of science process skills and scientific attitudes are taken from observational and performance instruments. Data analysis used are descriptive statistics and correlation. The results show that: 1) the physics practicum can train the science process skills and scientific attitudes in good category, 2) the relationship between the science process skills and the students' scientific attitude is good category 3) Student responses to the learning process using the practicum in the good category, The results of the research conclude that the physics practicum can train the science process skill and have a significant effect on the scientific attitude of the vocational highschool students.

Creating a Sustainable and Supportive Teaching Practicum in Rural and Regional Locations

ERIC Educational Resources Information Center

Ryan, Josephine; Jones, Melitta; Walta, Caroline

2012-01-01

The study described in this paper Creating an effective practicum model for rural and regional preservice teachers is designed to address the ongoing difficulties experienced by schools and universities as they seek to provide high quality preservice teacher education for individuals in rural areas. Lecturers from the regional campuses of two…

Vertical Structure of the Urban Boundary Layer over Marseille Under Sea-Breeze Conditions

NASA Astrophysics Data System (ADS)

Lemonsu, Aude; Bastin, Sophie; Masson, Valéry; Drobinski, Philippe

2006-03-01

During the UBL-ESCOMPTE program (June July 2001), intensive observations were performed in Marseille (France). In particular, a Doppler lidar, located in the north of the city, provided radial velocity measurements on a 6-km radius area in the lowest 3 km of the troposphere. Thus, it is well adapted to document the vertical structure of the atmosphere above complex terrain, notably in Marseille, which is bordered by the Mediterranean sea and framed by numerous massifs. The present study focuses on the last day of the intensive observation period 2 (26 June 2001), which is characterized by a weak synoptic pressure gradient favouring the development of thermal circulations. Under such conditions, a complex stratification of the atmosphere is observed. Three-dimensional numerical simulations, with the Méso-NH atmospheric model including the town energy balance (TEB) urban parameterization, are conducted over south-eastern France. A complete evaluation of the model outputs was already performed at both regional and city scales. Here, the 250-m resolution outputs describing the vertical structure of the atmosphere above the Marseille area are compared to the Doppler lidar data, for which the spatial resolution is comparable. This joint analysis underscores the consistency between the atmospheric boundary layer (ABL) observed by the Doppler lidar and that modelled by Méso-NH. The observations and simulations reveal the presence of a shallow sea breeze (SSB) superimposed on a deep sea breeze (DSB) above Marseille during daytime. Because of the step-like shape of the Marseille coastline, the SSB is organized in two branches of different directions, which converge above the city centre. The analysis of the 250-m wind fields shows evidence of the role of the local topography on the local dynamics. Indeed, the topography tends to reinforce the SSB while it weakens the DSB. The ABL is directly affected by the different sea-breeze circulations, while the urban effects appear

Students' approaches to learning in a clinical practicum: A psychometric evaluation based on item response theory.

PubMed

Zhao, Yue; Kuan, Hoi Kei; Chung, Joyce O K; Chan, Cecilia K Y; Li, William H C

2018-07-01

The investigation of learning approaches in the clinical workplace context has remained an under-researched area. Despite the validation of learning approach instruments and their applications in various clinical contexts, little is known about the extent to which an individual item, that reflects a specific learning strategy and motive, effectively contributes to characterizing students' learning approaches. This study aimed to measure nursing students' approaches to learning in a clinical practicum using the Approaches to Learning at Work Questionnaire (ALWQ). Survey research design was used in the study. A sample of year 3 nursing students (n = 208) who undertook a 6-week clinical practicum course participated in the study. Factor analyses were conducted, followed by an item response theory analysis, including model assumption evaluation (unidimensionality and local independence), item calibration and goodness-of-fit assessment. Two subscales, deep and surface, were derived. Findings suggested that: (a) items measuring the deep motive from intrinsic interest and deep strategies of relating new ideas to similar situations, and that of concept mapping served as the strongest discriminating indicators; (b) the surface strategy of memorizing facts and details without an overall picture exhibited the highest discriminating power among all surface items; and, (c) both subscales appeared to be informative in assessing a broad range of the corresponding latent trait. The 21-item ALWQ derived from this study presented an efficient, internally consistent and precise measure. Findings provided a useful psychometric evaluation of the ALWQ in the clinical practicum context, added evidence to the utility of the ALWQ for nursing education practice and research, and echoed the discussions from previous studies on the role of the contextual factors in influencing student choices of different learning strategies. They provided insights for clinical educators to measure

Mental Health Nursing Practicum: Student and Mentor Perspectives on Stress and Satisfaction

ERIC Educational Resources Information Center

Gelabert-Vilella, Sandra; Bonmati-Tomàs, Anna; Bosch-Farré, Cristina; Malagón-Aguilera, M. Carmen; Fuentes-Pumarola, Concepció; Ballester-Ferrando, David

2014-01-01

Nursing students begin to complete practicum experiences during their first year, increasing the number of applied credits as they progress toward degree completion. This contributes to integrating knowledge and skills from all of their courses and to obtaining the basic competencies of the nursing profession. It is also essential to identify the…

Development of a Model for Planning an Educational Facility. [A] Practicum Report.

ERIC Educational Resources Information Center

Boughner, Wesley; And Others

This publication is composed of two separate entities: a relatively brief manuscript entitled "Development of a Model for Planning an Educational Facility" and a much more lengthy Midi-Practicum Report that describes the implementation of the plans outlined in the first manuscript. Each of the three authors wrote one section of the first…

Effects of a senior practicum course on nursing students' confidence in speaking up for patient safety.

PubMed

Kent, Lauren; Anderson, Gabrielle; Ciocca, Rebecca; Shanks, Linda; Enlow, Michele

2015-03-01

As patient advocates, nurses are responsible for speaking up against unsafe practices. Nursing students must develop the confidence to speak up for patient safety so that they can hold themselves, as well as their peers and coworkers, accountable for patients' well-being. The purpose of this study was to examine the effects of a senior practicum course on confidence for speaking up for patient safety in nursing students. Confidence in speaking up for patient safety was measured with the Health Professional Education in Patient Safety Survey. The study showed a significant increase in nursing students' confidence after the senior practicum course, but there was no significant change in students' confidence in questioning someone of authority. Copyright 2015, SLACK Incorporated.

"L'arte D'arrangiarsi": Evaluation of an Innovative Practice in a Preservice Practicum

ERIC Educational Resources Information Center

Macy, Marisa; Squires, Jane

2009-01-01

Building on Opportunities for Student Teaching and Learning (BOOST) is a community-based summer preschool program developed, implemented, and coordinated by student teachers, university supervisors, and faculty. Ten preservice graduate students participated in BOOST practicum activities during the spring and summer terms of their 1-year Early…

Practicum Learnings for Counseling and Art Therapy Students: The Shared and the Particular

ERIC Educational Resources Information Center

Van Lith, Theresa; Voronin, Lorelei

2016-01-01

Practicum experience in counseling and therapy training can be an anxiety-inducing time as students begin to apply their acquired theoretical knowledge. On-site supervisors closely monitor students' development by making use of example-based involvements to provide valuable insights and learning opportunities. This paper examines the findings from…

78 FR 39062 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel SEA BREEZE 27; Invitation for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-28

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013 0079] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel SEA BREEZE 27; Invitation for Public Comments AGENCY....gov . SUPPLEMENTARY INFORMATION: As described by the applicant the intended service of the vessel SEA...

Diurnal Course of Evaporation From the Dead Sea in Summer: A Distinct Double Peak Induced by Solar Radiation and Night Sea Breeze

NASA Astrophysics Data System (ADS)

Lensky, N. G.; Lensky, I. M.; Peretz, A.; Gertman, I.; Tanny, J.; Assouline, S.

2018-01-01

Partitioning between the relative effects of the radiative and aerodynamic components of the atmospheric forcing on evaporation is challenging since diurnal distributions of wind speed and solar radiation typically overlap. The Dead Sea is located about a 100 km off the Eastern Mediterranean coast, where and the Mediterranean Sea breeze front reaches it after sunset. Therefore, in the Dead Sea the peaks of solar radiation and wind speed diurnal cycles in the Dead Sea are distinctly separated in time, offering a unique opportunity to distinguish between their relative impacts on evaporation. We present mid-summer eddy covariance and meteorological measurements of evaporation rate and surface energy fluxes over the Dead Sea. The evaporation rate is characterized by a clear diurnal cycle with a daytime peak, few hours after solar radiation peak, and a nighttime peak coincident with wind speed peak. Evaporation rate is minimum during sunrise and sunset. Measurements of evaporation rate from two other water bodies that are closer to the Mediterranean coast, Eshkol Reservoir, and Lake Kinneret, present a single afternoon peak, synchronous with the sea breeze. The inland diurnal evaporation rate cycle varies with the distance from the Mediterranean coast, following the propagation of sea breeze front: near the coast, wind speed, and radiation peaks are close and consequently a single daily evaporation peak appears in the afternoon; at the Dead Sea, about a 100 km inland, the sea breeze front arrives at sunset, resulting in a diurnal evaporation cycle characterized by a distinct double peak.

Alberta's Student Teacher Practicum: A Legal Analysis of the Statutory and Regulatory Framework

ERIC Educational Resources Information Center

Donlevy, J. Kent

2009-01-01

In 2005, a total of approximately 2, 915 student teachers were placed for practicum purposes in Alberta's schools by the five Alberta universities which offer teacher preparation programs leading to the Bachelor of Education degree: the University of Alberta, the University of Calgary, the University of Lethbridge, King's University College, and…

Student-Teachers' Strategies in Classroom Interaction in the Context of the Teaching Practicum

ERIC Educational Resources Information Center

Heikonen, Lauri; Toom, Auli; Pyhältö, Kirsi; Pietarinen, Janne; Soini, Tiina

2017-01-01

Strategies student-teachers employ in classroom interaction with pupils during teaching practice periods are surprisingly understudied, considering that the teaching practicum provides a central arena for student-teachers learning to become teachers. This study investigates the primary strategies student-teachers utilised in classroom interaction…

The Perception-Practicum Interface Revisited: Life-Wise Language Teaching Perceptions and Teacher Burnout

ERIC Educational Resources Information Center

Pishghadam, Reza; Zabihi, Reza; Shayesteh, Shaghayegh

2014-01-01

Although a great deal of research in education has been devoted to examining several causes of teacher burnout, relatively little of that work has considered the role of teachers' perceptions of their profession in the formation or alleviation of this syndrome. Thus, given the importance of the perception-practicum interface in English language…

Footy, Gangs and Love: Using Auto-Ethnography to Problematise Practice on a Practicum

ERIC Educational Resources Information Center

Bellamy, Roz

2017-01-01

This article was written as an auto ethnography, which allowed for a complex and personal exploration of professional standards, teachers' professional identities, neoliberal reforms, and approaches to literacy and creativity. This article reflects on a practicum which involved teaching Romeo and Juliet to two year nine classes at an all boys'…

Cultivating Pre-Service Teachers' Classroom Management Skills through Teaching Practicum: A Reflective Practice

ERIC Educational Resources Information Center

Ragawanti, Debora Tri

2015-01-01

Classroom management is commonly believed to be the key to the success of an instruction. Many student teachers, however, might find it very challenging to handle their classrooms. It is, therefore, necessary to advance their professional practice in the context of a real classroom such as through teaching practicum and reflective practice. This…

Improving Child Management Practices of Parents and Teachers. Maxi I Practicum. Final Report.

ERIC Educational Resources Information Center

Adreani, Arnold J.; McCaffrey, Robert

The practicum design reported in this document was based on one basic assumption, that the adult perceptions of children influence adult behavior toward children which in turn influences the child's behavior. Therefore, behavior changes by children could best be effected by changing the adult perception of, and behavior toward, the child.…

Enhancing the Practicum Experience for Pre-service Chemistry Teachers Through Collaborative CoRe Design with Mentor Teachers

NASA Astrophysics Data System (ADS)

Hume, Anne; Berry, Amanda

2013-10-01

This paper reports findings from an ongoing study exploring how the Content Representation (CoRe) design can be used as a tool to help chemistry student teachers begin acquiring the professional knowledge required to become expert chemistry teachers. Phase 2 of the study, reported in this paper, investigated how collaboration with school-based mentors (associate teachers) on teaching practice (practicum) might impact on this process and student teachers' development of their pedagogical content knowledge (PCK). The collaboration involved identifying and discussing pedagogical issues related to a practicum-teaching topic using a student teacher's draft CoRe as a starting point and ongoing focus for the professional dialogue. Practicum offered an opportunity for aspects of student teachers' PCK, as embodied in their draft CoRes, to be explored and expanded upon in classroom programmes with the support and input of associate teachers. The findings were influenced by different contextual factors; however, the student teachers found their CoRes to be very useful frameworks for engaging in focussed professional dialogue with their teaching mentors. They valued the expertise, currency of knowledge and mentoring of their associates and reported positively about the contribution this support made to their PCK development via the CoRe design process and the transformation of the CoRe into classroom teaching.

Assessing Self-Efficacy Beliefs of Students Enrolled in Early Childhood Education Practicum Movement Courses

ERIC Educational Resources Information Center

Johnson, Lisa B.

2016-01-01

The purpose of this study was to assess self- efficacy beliefs of students in early childhood education movement practicum courses offered in Northeastern Ohio higher educational institutions. The sample population consisted of early childhood education students from four higher educational institutions (two community colleges and two…

Marketing. Retailing 102, Promotions 202, Relations in Business 202, Management 302, Marketing Practicum 302.

ERIC Educational Resources Information Center

Manitoba Dept. of Education, Winnipeg.

This teaching guide contains guidelines for conducting five secondary-level marketing cluster courses--Retailing 102, Promotions 202, Relations in Business 202, Management 302, and Marketing Practicum 302. Covered first are goals and objectives, teachers' notes and suggested activities, lists of suggested materials, and guidelines for correlating…

Counseling Skills Pre-Practicum Training at Guidance and Counseling Undergraduate Programs: A Qualitative Investigation

ERIC Educational Resources Information Center

Aladag, Mine

2013-01-01

This study was aimed to describe counseling skills pre-practicum training at guidance and counseling undergraduate programs in Turkey. A descriptive study was conducted based upon qualitative data. The research group of this study consisted of 11 guidance and counseling undergraduate programs voluntarily participate into study. The Survey Form…

Peer Mentoring: A Way forward for Supporting Preservice EFL Teachers Psychosocially during the Practicum

ERIC Educational Resources Information Center

Nguyen, Hoa Thi Mai

2013-01-01

During the past several years, the importance of practicum as a vital proportion of the preservice teacher education program has been increasingly emphasized. There have been a number of initiatives for supporting preservice teachers. Among these, peer based relationship is increasingly emerged as an innovative strategy to provide additional…

The Pygmalion Principle: The Practicum Expectations and Experiences of Mature Aged Student Teachers

ERIC Educational Resources Information Center

Etherington, Matthew

2011-01-01

This study was part of a larger on-going study that is examining the Pygmalion Principle for the practicum experiences of six mature-age student-teachers. The participants are former graduates with university degrees and aged from 36 to 49. They have extensive career backgrounds unrelated to classroom teaching. For this part of the larger study,…

Assessment of the Practicum by Students from the Perspective of the Induction Process

ERIC Educational Resources Information Center

Pacios, Ana R.

2013-01-01

This article shows the assessments made by students from the Carlos III University of Madrid of the induction period in the practicum they performed during their courses of study, and their perceptions of and attitudes towards it. The method used was a survey comprising 6 questions about the induction process, which was carried out among 359…

Nurturing nursing students during intensive care unit clinical practicum.

PubMed

Goldin, Marlienne; Kautz, Donald D

2010-01-01

Approximately one-third of new graduates will quit their jobs in the first year. When nurses leave, vacant positions result in increased overtime for the remaining staff, which eventually results in burnout. Burnout leads to even more turnover. This article describes how the staff transformed a neurosurgical intensive care unit and nurture students through the application of Jean Watson's 10 Caritas processes. When nursing students complete their clinical practicum in the unit, learning is enhanced, the students seek to continue to work in the intensive care unit, recruitment and retention are encouraged, and burnout may be prevented.

Assessing Teaching Practicum Reflections: Distinguishing Discourse Features of the "High" and "Low" Grade Reports

ERIC Educational Resources Information Center

Luk, Jasmine

2008-01-01

Using reflective journals to promote learning has been a common practice in the teaching profession. How learners present reflections in what are judged to be high-quality reflective writing remains under-researched. This paper explores the discourse features of teaching practicum reflective reports written by six pre-service student teachers of…

A Social Media Practicum: An Action-Learning Approach to Social Media Marketing and Analytics

ERIC Educational Resources Information Center

Atwong, Catherine T.

2015-01-01

To prepare students for the rapidly evolving field of digital marketing, which requires more and more technical skills every year, a social media practicum creates a learning environment in which students can apply marketing principles and become ready for collaborative work in social media marketing and analytics. Using student newspapers as…

Dangerous Practices: The Practicum Experiences of Non-Indigenous Pre-Service Teachers in Remote Communities

ERIC Educational Resources Information Center

Auld, Glenn; Dyer, Julie; Charles, Claire

2016-01-01

This paper seeks to explore the risks of providing preservice teachers with professional experiences in remote communities. In particular this paper focuses on the risks associated with this kind of professional experience. Twelve pre-service teachers were interviewed whilst on a three-week practicum around Katherine and in Maningrida in the…

Influence of sea-land breezes on the tempospatial distribution of atmospheric aerosols over coastal region.

PubMed

Tsai, Hsieh-Hung; Yuan, Chung-Shin; Hung, Chung-Hsuang; Lin, Chitsan; Lin, Yuan-Chung

2011-04-01

The influence of sea-land breezes (SLBs) on the spatial distribution and temporal variation of particulate matter (PM) in the atmosphere was investigated over coastal Taiwan. PM was simultaneously sampled at inland and offshore locations during three intensive sampling periods. The intensive PM sampling protocol was continuously conducted over a 48-hr period. During this time, PM2.5 and PM(2.5-10) (PM with aerodynamic diameters < 2.5 microm and between 2.5 and 10 microm, respectively) were simultaneously measured with dichotomous samplers at four sites (two inland and two offshore sites) and PM10 (PM with aerodynamic diameters < or =10 microm) was measured with beta-ray monitors at these same 4 sites and at 10 sites of the Taiwan Air Quality Monitoring Network. PM sampling on a mobile air quality monitoring boat was further conducted along the coastline to collect offshore PM using a beta-ray monitor and a dichotomous sampler. Data obtained from the inland sites (n=12) and offshore sites (n=2) were applied to plot the PM10 concentration contour using Surfer software. This study also used a three-dimensional meteorological model (Pennsylvania State University/National Center for Atmospheric Research Meteorological Model 5) and the Comprehensive Air Quality Model with Extensions to simulate surface wind fields and spatial distribution of PM10 over the coastal region during the intensive sampling periods. Spatial distribution of PM10 concentration was further used in investigating the influence of SLBs on the transport of PM10 over the coastal region. Field measurement and model simulation results showed that PM10 was transported back and forth across the coastline. In particular, a high PM10 concentration was observed at the inland sites during the day because of sea breezes, whereas a high PM10 concentration was detected offshore at night because of land breezes. This study revealed that the accumulation of PM in the near-ocean region because of SLBs influenced the

A Phenomenological Study: The Experience of Live Supervision during a Pre-Practicum Counseling Techniques Course

ERIC Educational Resources Information Center

Koltz, Rebecca L.; Feit, Stephen S.

2012-01-01

The experiences of live supervision for three, master's level, pre-practicum counseling students were explored using a phenomenological methodology. Using semi-structured interviews, this study resulted in a thick description of the experience of live supervision capturing participants' thoughts, emotions, and behaviors. Data revealed that live…

Reflective Practice and Self-Evaluation in Learning Positive Guidance: Experiences of Early Childhood Practicum Students

ERIC Educational Resources Information Center

McFarland, Laura; Saunders, Rachel; Allen, Sydnye

2009-01-01

This paper examines the role of self-reflection and self-evaluation in early childhood practicum students' development of positive guidance skills with children. We examine how helpful students find self-reflection and self-evaluation exercises and how their thoroughness of reflection relates to their progress in acquiring positive guidance…

Student Triads: A Collaborative Approach to Practicum Experiences for Master's Nursing Students.

PubMed

Goodwin, Miki; Jenkins-Weinrub, Edith

2015-01-01

This article presents an approach for a collaborative practicum experience for master's degree nursing students. The students were placed into triads and then assigned as a group to work in a large health care organization. A triad consisted of 1 student from each concentration of study: nursing administration, nursing education, or nursing informatics, and the group was immersed in real-time problem-solving and decision-making processes over the course of the year.

[An experience applying the teaching strategies of cooperative learning and creative thinking in a mental-health nursing practicum for undergraduates at a technical college].

PubMed

Huang, Yu-Hsien; Lin, Mei-Feng; Ho, Hsueh-Jen; Chang, Lu-Na; Chen, Shiue

2015-04-01

Lack of knowledge and experience is prevalent in undergraduate students who are taking their clinical practicum for mental-health nursing. This issue negatively affects the learning process. This article shares an experience of implementing a practicum-teaching program. This program was developed by the authors to facilitate the cooperative learning and clinical care competence of students. A series of multidimensional teaching activities was designed by integrating the strategies of peer cooperation and creative thinking to promote group and individual learning. Results indicate that the program successfully encouraged the students to participate more actively in the learning process. Additionally, the students demonstrated increased competence in empathetic caring toward patients, stronger friendship relationships with peers, and improved self-growth. The authors hope this teaching program provides a framework to increase the benefits for students of participating in clinical practicums and provides a teaching reference for clinical instructors.

A Systems Perspective on Practicum Experiences in Early Childhood Teacher Education: Focus on Interprofessional Relationships

ERIC Educational Resources Information Center

La Paro, Karen M.; Van Schagen, Amy; King, Elizabeth; Lippard, Christine

2018-01-01

High quality early childhood teachers have a wealth of knowledge and use a range of skills in their daily classroom practices, and research has consistently demonstrated the positive influence effective early childhood teachers have on children's development and long-term outcomes. Given the importance of practicum experiences in the development…

Experiences of Student Speech-Language Pathology Clinicians in the Initial Clinical Practicum: A Phenomenological Study

ERIC Educational Resources Information Center

Nelson, Lori A.

2011-01-01

Speech-language pathology literature is limited in describing the clinical practicum process from the student perspective. Much of the supervision literature in this field focuses on quantitative research and/or the point of view of the supervisor. Understanding the student experience serves to enhance the quality of clinical supervision. Of…

The monsoon system: Land-sea breeze or the ITCZ?

NASA Astrophysics Data System (ADS)

Gadgil, Sulochana

2018-02-01

For well over 300 years, the monsoon has been considered to be a gigantic land-sea breeze driven by the land-ocean contrast in surface temperature. In this paper, this hypothesis and its implications for the variability of the monsoon are discussed and it is shown that the observations of monsoon variability do not support this popular theory of the monsoon. An alternative hypothesis (whose origins can be traced to Blanford's (1886) remarkably perceptive analysis) in which the basic system responsible for the Indian summer monsoon is considered to be the Intertropical Convergence Zone (ITCZ) or the equatorial trough, is then examined and shown to be consistent with the observations. The implications of considering the monsoon as a manifestation of the seasonal migration of the ITCZ for the variability of the Indian summer monsoon and for identification of the monsoonal regions of the world are briefly discussed.

Cross-Cultural "Distance", "Friction" and "Flow": Exploring the Experiences of Pre-Service Teachers on International Practicum

ERIC Educational Resources Information Center

Uusimaki, Liisa; Swirski, Teresa

2016-01-01

The focus of this paper is to illustrate Australian regional pre-service teachers' perceptions of an international practicum: their cross-cultural understanding, notions of privilege and teacher/professional identity development. Findings indicate that there were three overlapping dimensions of cross-cultural understanding for pre-service…

The role of refinery flaring events and bay breezes on a high surface ozone episode during the Houston, Texas DISCOVER-AQ field campaign

NASA Astrophysics Data System (ADS)

Loughner, C.; Follette-Cook, M. B.; Fried, A.; Pickering, K. E.

2015-12-01

The highest observed surface ozone concentrations in the Houston metropolitan area in 2013 occurred on September 25, which coincided with the Texas DISCOVER-AQ (Deriving Information on Surface Conditions from Column and Vertically Resolved Observations Relevant to Air Quality) field campaign. Surface ozone was elevated throughout the Houston metropolitan area with maximum 8-hour average ozone peaking along the western shore of Galveston Bay, reaching 124 ppbv, almost 50 ppbv above the current EPA standard of 75 ppbv. The NASA P-3B aircraft observed plumes from refinery flares west and northwest of Galveston Bay that were transported over the water. Continental air pollution from the north was transported into the Houston metropolitan area where it mixed with locally generated emissions. A bay breeze circulation formed causing pollutants that were transported out over the water in the morning to recirculate back inland where they mixed with freshly emitted pollution near the bay breeze convergence zone. The highest surface ozone concentrations were reported near the bay breeze front. This ozone episode will be presented using measurements made during the DISCOVER-AQ field campaign and a CMAQ model simulation with integrated source apportionment, which tracks the contribution of emissions source groups and regions on ozone concentrations.

Scrutinizing Practicum for a More Powerful Teacher Education: A Longitudinal Study with Pre-Service Teachers

ERIC Educational Resources Information Center

Serdar Tülüce, Hande; Çeçen, Sevdeger

2016-01-01

This study aims to explore the role of school-based practicum in promoting pre-service English language teachers' professional development through the use of a longitudinal design in combination with qualitative methods. To achieve this aim, pre-service teachers were asked to successively reflect on video-recordings of their micro-lessons in their…

Utilizing TRMM to Analyze Sea Breeze Thunderstorm Patterns During El Nino Southern Oscillations and Their Effects upon Available Fresh Water for South Florida Agricultural Planning and Management

NASA Technical Reports Server (NTRS)

Cooley, Clayton; Billiot, Amanda; Lee, Lucas; McKee, Jake

2010-01-01

Water is in high demand for farmers regardless of where you go. Unfortunately, farmers in southern Florida have fewer options for water supplies than public users and are often limited to using available supplies from surface and ground water sources which depend in part upon variable weather patterns. There is an interest by the agricultural community about the effect weather has on usable surface water, however, research into viable weather patterns during La Nina and El Nino has yet to be researched. Using rainfall accumulation data from NASA Tropical Rainfall Measurement Mission (TRMM) satellite, this project s purpose was to assess the influence of El Nino and La Nina Oscillations on sea breeze thunderstorm patterns, as well as general rainfall patterns during the summer season in South Florida. Through this research we were able to illustrate the spatial and temporal variations in rainfall accumulation for each oscillation in relation to major agricultural areas. The study period for this project is from 1998, when TRMM was first launched, to 2009. Since sea breezes in Florida typically occur in the months of May through October, these months were chosen to be the months of the study. During this time, there were five periods of El Nino and two periods of La Nina, with a neutral period separating each oscillation. In order to eliminate rainfall from systems other than sea breeze thunderstorms, only days that were conducive to the development of a sea breeze front were selected.

Preventive practicum training in healthcare organizations. The Meharry model.

PubMed

Levine, R S; St Onge, J; Moriarty, C J; Bailey, S; Logan, T; Zhu, K; Nelson, B K; Hodder, R A; Marino, W

1999-07-01

Practicum training for preventive medicine residents often occurs in agencies whose community is geographically defined and whose governance is closely linked to public election. We were unsure about the financial ability of such departments to support training and are concerned that over-reliance on traditional health departments might not be best for either medically indigent populations or preventive medicine. We, therefore, sought to apply a public health model--based on a strategic partnership between nursing and preventive medicine--to a large health care organization. The result was formation of a mini-health department, suitable for fully accredited preventive medicine practicum training, within the Alvin C. York Veterans Affairs Medical Center, Murfreesboro, TN. This Center serves a defined population of 21,594 patients and about 1600 employees. The theoretical framework for the new department was based on demonstration of a close fit between the competencies expected of preventive medicine physicians by the American College of Preventive Medicine (ACPM) and activities required by the Joint Commission on Accreditation of Healthcare Organizations (JCAHO). Because of JCAHO requirements, many healthcare organizations already pay for preventive medicine services. By placing preventive medicine training faculty into existing budget slots at our institution, systemwide personnel costs for prevention decreased by about $36,000 per year, even as personnel funding for preventive medicine physicians increased from about $24,000 to $376,000 per year. Moreover, there was dramatic, sustained improvement in 17 indicators of preventive care quality as determined by an external peer review organization. In addition to providing a new venue for training, this model may also improve the quality and reach of preventive services, decreased fixed costs for service delivery, and yield new employment opportunities for preventive medicine physicians.

Facebook and the Final Practicum: The Impact of Online Peer Support in the Assistant Teacher Program

ERIC Educational Resources Information Center

Paris, Lisa F.; Boston, Julie; Morris, Julia

2015-01-01

Australian pre-service teachers (PST) frequently report feeling isolated and vulnerable during the high stakes Assistant Teacher Program (ATP) final practicum. Mentoring and online learning communities have been shown to offer effective support during periods in which pre-service and beginning teachers feel challenged. As social media…

Crying in the Halls: Supervising Students with Symptoms of Emotional Problems in the Clinical Practicum

ERIC Educational Resources Information Center

Storrie, Kim; Ahern, Kathy; Tuckett, Anthony

2012-01-01

There is evidence that the number of university students with mental health problems has increased over the past few years. The literature also suggests that the number and effect of troubled health science students create significant problems in the clinical practicum. However, there are gaps in the literature as to how clinical teachers actually…

Bridging Community Generational Gaps through Experiential Learning: A College Nursing Student Practicum for Elderly Patients

ERIC Educational Resources Information Center

Pate, Jane D.

2013-01-01

At the study site, an elder care practicum was adopted after nursing students demonstrated a lack of interest in the well-being of elderly patients. The purpose of the study was to determine if there was a change in college nursing students' attitudes toward nursing home residents as a result of increased intergenerational exposure following an…

Windows into Classrooms: Using ICT to Facilitate Regional, Rural and Remote Practicum and Teacher Professional Learning

ERIC Educational Resources Information Center

Romeo, Geoff; Gronn, Donna; McNamara, Sue; Teo, Yiong Hwee

2012-01-01

The purpose of this study was to field-test several conferencing technologies in regional schools in Victoria to determine whether the technologies are appropriate for the needs of the university supervisor, trainee teachers and supervising teachers with regard to practicum placements. The study also explored the potential of technology for other…

German Literature and Culture under "Revue": Learner Autonomy and Creativity through the Theme-Based Theater Practicum

ERIC Educational Resources Information Center

Koerner, Morgan

2012-01-01

This article proposes a theatrically oriented, thematically structured course model for the upper level undergraduate German curriculum. The traditional focus on staging a single play in the German foreign language theater practicum neglects theater's potential to explore other literary genres and cultural texts and runs the danger of…

When Communities Collide: The Shared Construction and Defence of Community and Identity during a Teaching Practicum

ERIC Educational Resources Information Center

Trent, John

2014-01-01

This article describes the results of a qualitative multiple case study investigation of the experiences of preservice teachers during a teaching practicum in Hong Kong. The study uses in-depth interviews with pairs of student teachers and their school-based supporting teachers to understand how the former positioned themselves as particular types…

Investigating the Stress Levels of Early Childhood, Primary and Secondary Pre-Service Teachers during Teaching Practicum

ERIC Educational Resources Information Center

Geng, Gretchen; Midford, Richard; Buckworth, Jenny

2015-01-01

This study investigated stress levels of pre-service teachers (PSTs) across three categories of teaching context: early childhood, primary and secondary. This paper focused on exploring the stressors in the completion of tasks in teaching practicum in the three categories of teaching context and an awareness of and access to support systems. The…

The Usage of Recycle Materials for Science Practicum: Is There Any Effect on Science Process Skills?

ERIC Educational Resources Information Center

Prajoko, Setiyo; Amin, Mohamad; Rohman, Fatchur; Gipayana, Muhana

2017-01-01

This study aimed at determining the effect of recycle materials usage for science practicum on students' basic science process skills of the Open University, Surakarta. Recycle materials are the term used for the obtained materials and equipment from the students' environment by taking back the garbage or secondhand objects into goods or new…

Reflective Practicum in Higher Education: The Influence of the Learning Environment on the Quality of Learning

ERIC Educational Resources Information Center

Bruno, Andreina; Dell'Aversana, Giuseppina

2018-01-01

Sustaining students in becoming reflective practitioners is considered as a valued outcome of higher education. The paper aims to evaluate the impact of the learning environment conditions inspired by Schön's theory of reflective practicum, by discussing a case study of a master's degree class. The learning environment was designed to sustain…

A study of atmospheric dispersion of radionuclides at a coastal site using a modified Gaussian model and a mesoscale sea breeze model

NASA Astrophysics Data System (ADS)

Venkatesan, R.; Mathiyarasu, R.; Somayaji, K. M.

Ground level concentration and sky-shine dose due to radioactive emissions from a nuclear power plant at a coastal site have been estimated using the standard Gaussian Plume Model (GPM) and the modified GPM suggested by Misra (Atmospheric Environment 14 (1980) 397), which incorporates fumigation effect under sea breeze condition. The difference in results between these two models is analysed in order to understand their significance and errors that would occur if proper choice were not made. Radioactive sky-shine dose from 41Ar, emitted from a 100 m stack of the nuclear plant is continuously recorded by environmental gamma dose monitors and the data is used to validate the modified GPM. It is observed that the dose values increase by a factor of about 2 times than those of the standard GPM estimates, up to a downwind distance of 6 km during sea breeze hours. In order to examine the dispersion of radioactive effluents in the mesoscale range, a sea breeze model coupled with a particle dispersion model is used. The deposited activity, thyroid dose and sky-shine radioactive dose are simulated for a range of 30 km. In this range, the plume is found to deviate from its straight-line trajectory, as otherwise assumed in GPM. A secondary maximum in the concentration and the sky-shine dose is also observed in the model results. These results are quite significant in realistically estimating the area affected under any unlikely event of an accidental release of radioactivity.

Observed and simulated sea breeze characteristics over Rayong coastal area, Thailand

NASA Astrophysics Data System (ADS)

Phan, Tung Thanh; Manomaiphiboon, Kasemsan

2012-05-01

This work presents the detailed characterization of sea breeze (SB) over the Rayong coastal area, one of the most rapidly developed and highly industrialized areas during the last decade in Thailand, using observation data analysis and fine-resolution (2 km) mesoscale meteorological modeling with incorporation of new land cover and satellite-derived vegetation fraction data sets. The key characteristics considered include frequency of SB occurrence, sea-breeze day (SBD) identification, degree of inland penetration, and boundary layer development. It was found that SBs occur frequently in the winter due mainly to relatively large land-sea temperature contrasts and minimally in the wet season. Monthly mean SB onset and cessation times are at around 12-15 local time (LT) and 18-21 LT, respectively, and its strength peaks during the early- to mid-afternoon. Monthly SB hodographs generally exhibit clockwise rotations, and SB inland penetration (at PCD-T tower) ranges widely with the monthly means of 25-55 km from the coast. Mesoscale MM5 modeling was performed on two selected SBDs (13 January and 16 March 2006), on which the SBs are under weak and onshore strong influences from background winds, respectively. Simulated near-surface winds and temperature were found to be in fair-to-acceptable agreement with the observations. The SB circulation along the Rayong coast is clearly defined with a return flow aloft and a front on 13 January, while it is enhanced by the onshore background winds on 16 March. Another SB along the Chonburi coast also develops separately, but their fronts merge into one in the mid-afternoon, resulting in large area coverage by the SB. Simulated planetary boundary layer height over the land area is significantly affected by a thermal internal boundary layer (TIBL) induced by an SB, which is found to be low near the coast and increases toward the front (up to 800-1,000 m along the Rayong coast).

"I Couldn't Have Learned This Any Other Way": Learning to Teach Literacy across Concurrent Practicum Experiences

ERIC Educational Resources Information Center

Mosley Wetzel, Melissa; L. Roser, Nancy; Hoffman, James V.; Antonio Martínez, Ramón; Price-Dennis, Detra

2016-01-01

The authors, a team of literacy teacher educators who are focused on extending our own understandings of preservice teacher (PST) learning, conducted a cross-case analysis of how PSTs learned to teach literacy in three concurrent practicum experiences. We draw on Grossman's framework of representations, decompositions, and approximations to…

An Israeli haboob: Sea breeze activating local anthropogenic dust sources in the Negev loess

NASA Astrophysics Data System (ADS)

Crouvi, Onn; Dayan, Uri; Amit, Rivka; Enzel, Yehouda

2017-02-01

Meso-scale weather systems, such as convective haboobs, are considered to be an important dust generation mechanism. In Israel, however, rather than of meso-scale weather systems, most dust storms are generated by synoptic-scale systems, originating from Sahara and Arabia. Consequently, only distal sources of suspended and deposited dust in Israel are currently reported. Here we report the first detailed study on the merging of synoptic- and meso-scale weather systems leading to a prominent dust outbreak over the Negev, Israel. During the afternoon of May 2nd, 2007, a massive dust storm covered the northern Negev, forming a one kilometer high wall of dust. The haboob was associated with PM10 concentrations of 1000-1500 μg m-3 that advanced at a speed of 10-15 m s-1 and caused temporary closure of local airports. In contrast to most reported haboobs, this one was generated by a sea breeze front acting as a weak cold front enhanced by a cold core cyclone positioned over Libya and Egypt. The sea breeze that brought cold and moist marine air acted as a gravity current with strong surface winds. The sources for the haboob were the loessial soils of the northwestern Negev, especially agricultural fields that were highly disturbed in late spring to early summer. Such surface disturbance is caused by agricultural and/or intensive grazing practices. Our study emphasizes the importance of local dust sources in the Negev and stresses loess recycling as an important process in contemporary dust storms over Israel.

Learning "Rules" of Practice within the Context of the Practicum Triad: A Case Study of Learning to Teach

ERIC Educational Resources Information Center

Chalies, Sebastien; Escalie, Guillaume; Stefano, Bertone; Clarke, Anthony

2012-01-01

This case study sought to determine the professional development circumstances in which a preservice teacher learned rules of practice (Wittgenstein, 1996) on practicum while interacting with a cooperating teacher and university supervisor. Borrowing from a theoretical conceptualization of teacher professional development based on the postulates…

In Search of Teaching Quality of EFL Student Teachers through Teaching Practicum: Lessons from a Teacher Education Program

ERIC Educational Resources Information Center

Azkiyah, Siti Nurul; Mukminin, Amirul

2017-01-01

This study was intended to investigate the teaching quality of student teachers when they conducted their teaching practicum. Teaching quality is conceptualised based on eight classroom factors (orientation, structuring, modelling, application, questioning, building classroom as a learning environment, assessment, and time management) of the…

The Daily Events and Emotions of Master's-Level Family Therapy Trainees in Off-Campus Practicum Settings

ERIC Educational Resources Information Center

Edwards, Todd M.; Patterson, Jo Ellen

2012-01-01

The Day Reconstruction Method (DRM) was used to assess the daily events and emotions of one program's master's-level family therapy trainees in off-campus practicum settings. This study examines the DRM reports of 35 family therapy trainees in the second year of their master's program in marriage and family therapy. Four themes emerged from the…

Practicum as a Space and Time of Transformation: Self-Narrative of a Physical Education Pre-Service Teacher

ERIC Educational Resources Information Center

Margarida, Alves; Ana, Pereira; Amandio, Graca; Paula, Batista

2012-01-01

Understanding the role of the practicum in the PI (professional identity) construction and reconstruction within a pre-service teacher is crucial, since this is a remarkable moment in their initial training. This moment provides new feelings and challenges, and it represents the transition from students (pre-service teacher) to teachers…

Learning to Teach English Language in the Practicum: What Challenges do Non-Native ESL Student Teachers Face?

ERIC Educational Resources Information Center

Gan, Zhengdong

2013-01-01

This study investigates the challenges sixteen non-native preservice ESL teachers in a Bachelor of Education (English Language) (BEdEL) programme from Hong Kong experienced in an eight-week teaching practicum. Qualitative data from semi-structured interviews and reflective journals were collected from all 16 participants to obtain a detailed…

Interaction between turbulent flow and sea breeze front over urban-like coast in large-eddy simulation

NASA Astrophysics Data System (ADS)

Jiang, Ping; Wen, Zhiping; Sha, Weiming; Chen, Guixing

2017-05-01

Turbulent flow and its interaction with a sea breeze front (SBF) over an urban-like coast with a regular block array were investigated using a building-resolving computational fluid dynamics model. It was found that during daytime with an offshore ambient flow, streaky turbulent structures tended to grow within the convective boundary layer (CBL) over a warm urban surface ahead of the SBF. The structures were organized as streamwise streaks at an interval of a few hundred meters, which initiated at the rooftop level with strong wind shear and strengthens in the CBL with moderate buoyancy. The streaks then interacted with the onshore-propagating SBF as it made landfall. The SBF, which was initially characterized as a shallow and quasi-linear feature over the sea, developed three-dimensional structures with intensified updrafts at an elevated frontal head after landfall. Frontal updrafts were locally enhanced at intersections where the streaks merged with the SBF, which greatly increased turbulent fluxes at the front. The frontal line was irregular because of merging, tilting, and transformation effects of vorticity associated with streaky structures. Inland penetration of the SBF was slowed by the frictional effect of urban-like surfaces and turbulent flow on land. The overall SBF intensity weakened after the interaction with turbulent flow. These findings aid understanding of local weather over coastal cities during typical sea breeze conditions.

"We Were the Real Teacher": Outcomes of an International Practicum in the Solomon Islands for Australian Preservice Teachers

ERIC Educational Resources Information Center

Cinelli, Renata; Jones, Mellita

2017-01-01

International teaching experiences are touted as an opportunity for preservice teachers (PSTs) to grow both personally and professionally, including increased cultural awareness, self-efficacy, independence, and enhanced key teaching attributes. The study reported in this paper explores the outcomes of a four-week international practicum in the…

Mesoscale Simulations of a Florida Sea Breeze Using the PLACE Land Surface Model Coupled to a 1.5-Order Turbulence Parameterization

NASA Technical Reports Server (NTRS)

Lynn, Barry H.; Stauffer, David R.; Wetzel, Peter J.; Tao, Wei-Kuo; Perlin, Natal; Baker, R. David; Munoz, Ricardo; Boone, Aaron; Jia, Yiqin

1999-01-01

A sophisticated land-surface model, PLACE, the Parameterization for Land Atmospheric Convective Exchange, has been coupled to a 1.5-order turbulent kinetic energy (TKE) turbulence sub-model. Both have been incorporated into the Penn State/National Center for Atmospheric Research (PSU/NCAR) mesoscale model MM5. Such model improvements should have their greatest effect in conditions where surface contrasts dominate over dynamic processes, such as the simulation of warm-season, convective events. A validation study used the newly coupled model, MM5 TKE-PLACE, to simulate the evolution of Florida sea-breeze moist convection during the Convection and Precipitation Electrification Experiment (CaPE). Overall, eight simulations tested the sensitivity of the MM5 model to combinations of the new and default model physics, and initialization of soil moisture and temperature. The TKE-PLACE model produced more realistic surface sensible heat flux, lower biases for surface variables, more realistic rainfall, and cloud cover than the default model. Of the 8 simulations with different factors (i.e., model physics or initialization), TKE-PLACE compared very well when each simulation was ranked in terms of biases of the surface variables and rainfall, and percent and root mean square of cloud cover. A factor separation analysis showed that a successful simulation required the inclusion of a multi-layered, land surface soil vegetation model, realistic initial soil moisture, and higher order closure of the planetary boundary layer (PBL). These were needed to realistically model the effect of individual, joint, and synergistic contributions from the land surface and PBL on the CAPE sea-breeze, Lake Okeechobee lake breeze, and moist convection.

Design of a Competency Evaluation Model for Clinical Nursing Practicum, Based on Standardized Language Systems: Psychometric Validation Study.

PubMed

Iglesias-Parra, Maria Rosa; García-Guerrero, Alfonso; García-Mayor, Silvia; Kaknani-Uttumchandani, Shakira; León-Campos, Álvaro; Morales-Asencio, José Miguel

2015-07-01

To develop an evaluation system of clinical competencies for the practicum of nursing students based on the Nursing Interventions Classification (NIC). Psychometric validation study: the first two phases addressed definition and content validation, and the third phase consisted of a cross-sectional study for analyzing reliability. The study population was undergraduate nursing students and clinical tutors. Through the Delphi technique, 26 competencies and 91 interventions were isolated. Cronbach's α was 0.96. Factor analysis yielded 18 factors that explained 68.82% of the variance. Overall inter-item correlation was 0.26, and total-item correlation ranged between 0.66 and 0.19. A competency system for the nursing practicum, structured on the NIC, is a reliable method for assessing and evaluating clinical competencies. Further evaluations in other contexts are needed. The availability of standardized language systems in the nursing discipline supposes an ideal framework to develop the nursing curricula. © 2015 Sigma Theta Tau International.

Temperature And Wind Velocity Oscillations Along a Gentle Slope During Sea-Breeze Events

NASA Astrophysics Data System (ADS)

Bastin, Sophie; Drobinski, Philippe

2005-03-01

The flow structure on a gentle slope at Vallon d’Ol in the northern suburbs of Marseille in southern France has been documented by means of surface wind and temperature measurements collected from 7 June to 14 July 2001 during the ESCOMPTE experiment. The analysis of the time series reveals temperature and wind speed oscillations during several nights (about 60--90 min oscillation period) and several days (about 120-180 min oscillation period) during the whole observing period. Oscillating katabatic winds have been reported in the literature from theoretical, experimental and numerical studies. In the present study, the dynamics of the observed oscillating katabatic winds are in good agreement with the theory.In contrast to katabatic winds, no daytime observations of oscillating anabatic upslope flows have ever been published to our knowledge, probably because of temperature inversion break-up that inhibits upslope winds. The present paper shows that cold air advection by a sea breeze generates a mesoscale horizontal temperature gradient, and hence baroclinicity in the atmosphere, which then allows low-frequency oscillations, similar to a katabatic flow. An expression for the oscillation period is derived that accounts for the contribution of the sea-breeze induced mesoscale horizontal temperature gradient. The theoretical prediction of the oscillation period is compared to the measurements, and good agreement is found. The statistical analysis of the wind flow at Vallon d’Ol shows a dominant north-easterly to easterly flow pattern for nighttime oscillations and a dominant south-westerly flow pattern for daytime oscillations. These results are consistent with published numerical simulation results that show that the air drains off the mountain along the maximum slope direction, which in the studied case is oriented south-west to north-east.

Investigating Pre-Service EFL Teachers' Self-Concepts within the Framework of Teaching Practicum in Turkish Context

ERIC Educational Resources Information Center

Yilmaz, Cevdet

2018-01-01

The present study aimed at understanding the nature and potential dynamism of five pre-service EFL teachers' self-concepts in the domain of English as a foreign language (EFL). To this end, the effects of pre-service teachers' experiences gained alongside the practicum on their EFL self-concept development were also discussed. Data were generated…

Application of pedagogy reflective in statistical methods course and practicum statistical methods

NASA Astrophysics Data System (ADS)

Julie, Hongki

2017-08-01

Subject Elementary Statistics, Statistical Methods and Statistical Methods Practicum aimed to equip students of Mathematics Education about descriptive statistics and inferential statistics. The students' understanding about descriptive and inferential statistics were important for students on Mathematics Education Department, especially for those who took the final task associated with quantitative research. In quantitative research, students were required to be able to present and describe the quantitative data in an appropriate manner, to make conclusions from their quantitative data, and to create relationships between independent and dependent variables were defined in their research. In fact, when students made their final project associated with quantitative research, it was not been rare still met the students making mistakes in the steps of making conclusions and error in choosing the hypothetical testing process. As a result, they got incorrect conclusions. This is a very fatal mistake for those who did the quantitative research. There were some things gained from the implementation of reflective pedagogy on teaching learning process in Statistical Methods and Statistical Methods Practicum courses, namely: 1. Twenty two students passed in this course and and one student did not pass in this course. 2. The value of the most accomplished student was A that was achieved by 18 students. 3. According all students, their critical stance could be developed by them, and they could build a caring for each other through a learning process in this course. 4. All students agreed that through a learning process that they undergo in the course, they can build a caring for each other.

Experience preferred: insights from our newest public health professionals on how internships/practicums promote career development.

PubMed

Hernandez, Kristen E; Bejarano, Sandra; Reyes, Francis J; Chavez, Margarita; Mata, Holly

2014-01-01

Universities offering undergraduate degrees in health promotion or health education and/or graduate degrees in public health typically require an internship, practicum, or fieldwork experience. This type of mentored experience is an important aspect of career development for the next generation of public health professionals and benefits not only the students but also the profession and the communities in which they work. This article provides perspectives from four public health professionals who have recently graduated from designated minority-serving institutions and highlights the ways in which internship, practicum, or fieldwork experiences have contributed to their career development. From a career development perspective, internships provide unique opportunities to develop professional networks, practice competencies learned in the classroom, gain experience in different environments, and share lessons learned with others in our field. The diversification of the public health research and practice workforce is increasingly recognized as crucial in building health equity. Internship programs that focus specifically on the academic and professional development of students underrepresented in public health provide experiences that meet or supplement academic requirements, and provide students with real-world experience and an expanded network of mentors and role models.

[Selecting methods and awaiting growth: the teaching experience of fundamental nursing practicum instructors].

PubMed

Lin, Hui-Chen; Lin, Chi-Yi; Chien, Tsui-Wei; Liu, Kuei-Fen; Chen, Miao-Yen; Lin, Wen-Chuan

2013-02-01

A constellation of factors accounts for teaching efficacy in the fundamental nursing practicum. Teachers play a critical role in terms of designing and executing an appropriate teaching plan, choosing effective methods, and holding appropriate teaching attitudes. It is thus extremely important that clinical teachers master the core characteristics of basic nursing practice. This study aimed to illuminate the core characteristics of basic nursing practice for students for reference by clinical practicum teachers. Qualitative research was used to identify the fundamentals of nursing practice by clinical teacher. Five focus group meetings were convened during the practice period. The researchers presided over group discussions held during the normal weekly teaching schedule and lasting approximately 2-4 hours each. The content analysis was adopted to analyze the data. Three major themes were proposed, including (1) student status: "novices were stymied by problems and thus improved slowly"; (2) teacher awareness: "teachers need to be aware of student capabilities, mood, and discomfort"; and (3) teaching style: "a good choice of methods should support and encourage students. To cultivate professional nursing knowledge and self-confidence for future professional commitment, clinical teachers must first understand the characteristics and motivations of learning of their students and then select the, skills, and attitudes appropriate to provide step-by-step guidance. Communication with staffs and the preparation of atmosphere prior to nursing practice are also essential for students. Results provide insights into the technical college environment with regard to basic-level clinical nursing practice.

Regulating the Writing Process in the Teacher Training Practicum Guided by Feedback at the University of Barcelona

ERIC Educational Resources Information Center

Vidiella, Maria-Cinta Portillo; Garcia, Elena Cano

2016-01-01

This is a longitudinal study that focuses on blog-writing for the purpose of self-assessing competencies, and which was carried out within the practicum of a degree course in Primary Education Teaching at the University of Barcelona. Over the course of three academic years, students and a teacher have used a Platform 2.0 program, specially created…

Opportunities and Challenges for Practical Training in Public Health: Insights from Practicum Coordinators in Ontario.

PubMed

Wegener, Jessica; Petitclerc, Marilyne

2018-06-12

Dietetic educators and practicum coordinators (PC) play critical roles in preparing students for practice. Dietitians have made significant progress in the development of educational curricula, competencies, and other resources to support knowledge and skill attainment in public health. There are identified gaps in the literature concerning practical training in sustainable food systems and public health, creating barriers in knowledge exchange and improvements in practicum programs in Canada. This paper discusses the potential opportunities and challenges associated with the number of placements for practical training in public health based on interviews with PCs in Ontario. The findings are limited to the perspectives of 7 PCs with experience in practical training and are a starting point for ongoing evaluation. Identified opportunities within traditional and "emerging settings" for practical training in public health included: the uniqueness of the experience, the potential for students to learn outside their comfort zones, and greater possibilities for dietitians in new roles and settings. Challenges included the need for significant PC engagement with nondietetic preceptors and a narrow view of dietetic practice among some dietitians. Interprofessional teams, emerging settings, and flexible learning approaches may create and support practical training opportunities in food systems and public health going forward.

Grappling with Culturally Responsive Pedagogy: A Study of Elementary-Level Teacher Candidates' Learning across Practicum and Diversity Coursework Experiences

ERIC Educational Resources Information Center

Daniel, Shannon M.

2016-01-01

This investigation of teacher candidates' (TCs) learning in their pre-service elementary education program demonstrates how TCs grappled with enacting culturally responsive pedagogy (CRP) in their practicum sites. Interviews with TCs, analyzed with Lucas and Villegas's (2002) tenets of CRP, reveal how TCs thought about equitable instruction in…

What about Me?: A Practicum Addressing the Needs of Children Who Have a Preschool Sibling with Impaired Hearing.

ERIC Educational Resources Information Center

Weston, Marsha C.

This practicum developed a special program to serve the elementary school child who has a preschool sibling with a hearing impairment. A special book addressing the cognitive and emotional needs of the siblings was written and distributed to 35 children whose families were enrolled in a clinic-sponsored correspondence program and to 15 children…

Florida Agriculture - Utilizing TRMM to Analyze Sea Breeze Thunderstorm Patterns During El Nino Southern Oscillations and Their Effects Upon Available Fresh Water for South Florida Agricultural Planning and Management

NASA Technical Reports Server (NTRS)

Billiot, Amanda; Lee, Lucas; McKee, Jake; Cooley, Zachary Clayton; Mitchell, Brandie

2010-01-01

This project utilizes Tropical Rainfall Measuring Mission (TRMM) and Landsat satellite data to assess the impact of sea breeze precipitation upon areas of agricultural land use in southern Florida. Water is a critical resource to agriculture, and the availability of water for agricultural use in Florida continues to remain a key issue. Recent projections of statewide water use by 2020 estimate that 9.3 billion gallons of water per day will be demanded, and agriculture represents 47% of this demand (Bronson 2003). Farmers have fewer options for water supplies than public users and are often limited to using available supplies from surface and ground water sources which depend in part upon variable weather patterns. Sea breeze thunderstorms are responsible for much of the rainfall delivered to Florida during the wet season (May-October) and have been recognized as an important overall contributor of rainfall in southern Florida (Almeida 2003). TRMM satellite data was used to analyze how sea breeze-induced thunderstorms during El Nino and La Nina affected interannual patterns of precipitation in southern Florida from 1998-2009. TRMM's Precipitation Radar and Microwave Imager provide data to quantify water vapor in the atmosphere, precipitation rates and intensity, and the distribution of precipitation. Rainfall accumulation data derived from TRMM and other microwave sensors were used to analyze the temporal and spatial variations of rainfall during each phase of the El Nino Southern Oscillation (ENSO). Through the use of TRMM and Landsat, slight variations were observed, but it was determined that neither sea breeze nor total rainfall patterns in South Florida were strongly affected by ENSO during the study period. However, more research is needed to characterize the influence of ENSO on summer weather patterns in South Florida. This research will provide the basis for continued observations and study with the Global Precipitation Measurement Mission.

The Efficacy of Consulting Practicum in Enhancing Students' Readiness for Professional Career in Management Information Systems: An Empirical Analysis

ERIC Educational Resources Information Center

Akpan, Ikpe Justice

2016-01-01

Consulting practicum (CP) is a form of experiential learning technique to prepare students for professional careers. While CP has become a popular way to help students acquire the essential practical skills and experience to enhance career readiness and ensure a smooth transition from college to employment, there is a lack of empirical studies…

An Investigation of Preservice Early Childhood Teachers' Adoption of ICT in a Teaching Practicum Context in Hong Kong

ERIC Educational Resources Information Center

Hu, Xinyun; Yelland, Nicola

2017-01-01

The research reported here investigated the use of information and communication technologies (ICT) by 15 Hong Kong preservice early childhood teachers (PSTs) who had completed a course regarding the use of ICT in early childhood settings as they participated in their first-year teaching practicum. The study examined the preservice teachers use of…

First-Year Practicum Experiences for Preservice Early Childhood Education Teachers Working with Birth-to-3-Year-Olds: An Australasian Experience

ERIC Educational Resources Information Center

White, E. Jayne; Peter, Mira; Sims, Margaret; Rockel, Jean; Kumeroa, Maureen

2016-01-01

This article reports on a project, "Collaboration of Universities Pedagogies of Infants' and Toddlers' Development-'down under' (CUPID)," in which the practicum experiences of 1st-year preservice initial teacher education (ITE) students at five universities across Australia and New Zealand (NZ) engaging in early childhood education (ECE)…

An Examination of the Relationship between Supervision and Self-Efficacy in Early Career School Psychologists, School Psychology Interns, and Practicum Students

ERIC Educational Resources Information Center

Kaas, Felicia M.

2017-01-01

The purpose of this study is to explore the relationship between self-efficacy and supervision in early career school psychologists and school psychology graduate students who are currently completing either their practicum or internship experiences. The sample consisted of practicing early career school psychologists (ECPs) and school psychology…

Broadening of Graduate Practicums (An overview of how Jacksonville State University increased the practical experiences available to employed Master's level students).

ERIC Educational Resources Information Center

Frith, Greg

Educators agree that the interaction of teachers in training with exceptional children through the medium of practicums or internships is an essential component of every teacher education program. At the undergraduate level, where the student is usually pursuing a degree on a full time basis, ample opportunities exist for interaction with…

What Type of Feedback Do Student Teachers Expect from Their School Mentors during Practicum Experience? The Case of Spanish EFL Student Teachers

ERIC Educational Resources Information Center

Martínez Agudo, Juan de Dios

2016-01-01

Mentorship represents a vital component in all teacher education programmes since mentors' feedback plays an essential role in shaping candidate teachers' professional identity. The quality of feedback provided by school mentors during the practicum experience constitutes the main focus of this study. This research paper aimed at investigating…

Perceptions of Pre-Service Teachers on Mentor Teachers' Roles in Promoting Inclusive Practicum: Case Studies in U.S. Elementary School Contexts

ERIC Educational Resources Information Center

Maddamsetti, Jihea

2018-01-01

This case study examines a Chinese and Korean-Chinese pre-service teachers' perceptions of their mentor teachers' role in supporting inclusive practicum experiences in USA elementary school contexts. The findings demonstrate that a mentor teacher's open conversations and willingness to host those students bring positive influence on their learning…

Pre-Service Science Teachers' Views on Their Online Argumentation about What Is Happening in Middle School Science Classrooms during Their Practicum Period

ERIC Educational Resources Information Center

Kaya, Osman Nafiz; Dogan, Alev; Kilic, Ziya; Ebenezer, Jazlin

2004-01-01

In this study, Pre-service Science Teachers' (PSTs) views about the potential benefits and existing barriers of their argumentation on the World Wide Web about what is happening in middle school science classrooms during two semesters of their practicum experiences were investigated. "Special Web Group" called the "Collaborative…

Towards Collaborative Professional Learning in the First Year Early Childhood Teacher Education Practicum: Issues in Negotiating the Multiple Interests of Stakeholder Feedback

ERIC Educational Resources Information Center

Brown, Alice; Danaher, Patrick

2008-01-01

This paper analyses data from two sources of stakeholder feedback--first year pre-service teachers and supervising teachers/centre directors--about the issues involved in creating more collaborative approaches to the first year early childhood teacher education practicum at an Australian regional university. The collection of this feedback was…

The Virtual Clinical Practicum: an innovative telehealth model for clinical nursing education.

PubMed

Grady, Janet L

2011-01-01

The Virtual Clinical Practicum (VCP) involves a clinical nursing education delivery strategy that uses video teleconferencing technology to address time, distance, and resource barriers. Technology-delivered education can augment the existing curriculum by increasing student access to clinical experts in specialty areas, thus supporting efficient use of faculty resources. This article describes the implementation of the VCP process and student perceptions of its effectiveness and usefulness. The VCP was shown to be a successful method of clinical nursing education, offering students exposure to clinical situations not available by other means. Opportunities for dialogue, critical reflection, and synthesis allowed students to experience the benefits of a traditional experience, enhanced through technology and tailored to the specific needs of the students. Respondents overwhelmingly recommended further use of the VCP to augment existing clinical nursing education methods.

The nursing students' attitude toward using blogs in a nursing clinical practicum in Taiwan: a 3-R framework.

PubMed

Lin, Kai-Yin; Shen, Yen-Fen

2013-09-01

Some nursing educators have been using blogs as a channel to reflect on, share, and discuss questions and ideas for educational purpose. There were not many studies focused on the application of blog technology to the professional development of nursing education in Taiwan. The major goal of this study was to use a blog platform for students, writing their reflection notes, and observing the feedbacks from peers during their clinical practicum. Then we tried to probe the nursing students' attitude toward adopting 3-R categories based blog, which included wRiting reflection notes, Reading peers' notes, and Receiving peers' feedback. Of the 179 fourth grade from one five-year technical college students enrolled in a clinical practice course in Taiwan were used as a pool of sampling. Four-eight students were invited by the researcher to take part in this project. 90% of the participants agreed that blogs provided them with opportunities to share personal experiences with others. 81% of them valued that blogs provided opportunities to offering encouragement and emotional support to their peers. A majority of the participants believed that reading peers' journals was helpful in enhancing their professional development. In addition, all of them agreed that reading peers' journals can help them understand their peer's viewpoints. Most of the participants agreed that they were benefited through receiving feedbacks on the blogs. About 98% of them agreed that feedbacks can promote interaction with peers. The findings of this study generally indicated the participants' positive attitude toward using blogs in their clinical practicum. A majority of the participants also claimed that blogs provided them the opportunities to share personal experiences with their peers as well as to see things from their peers' viewpoints. They believed that reading peers' notes was helpful in enhancing their professional development. In addition, most of them agreed that receiving feedbacks

Could Practicum Placements in Contrasting Contexts Support the Preparation of Pre-Service Teachers for an Envisaged Inclusive Education System? A South African Study

ERIC Educational Resources Information Center

Rusznyak, Lee; Walton, Elizabeth

2017-01-01

In contexts where inclusive education is nascent, teacher educators face the challenge of preparing pre-service teachers for a system that does not yet exist. While this might be possible through university-based coursework, difficulties arise when so few sites that model inclusive pedagogies are available for practicum placements. This article…

Utilization of Innovations and Techniques of Educational Technology in Delivering of Educational Practicum and Its Impact on Increasing Academic Achievement among Pre-Service Teachers

ERIC Educational Resources Information Center

Ibrahim, Hatim G.

2017-01-01

The current study aims to identify the utilization of innovations and techniques of educational technology in teaching of educational practicum and its impact on increasing academic achievement among pre-service teachers. The study sample consisted of (60) pre-service teachers (student teachers) randomly selected from public middle and secondary…

Understanding Legitimate Teacher Authority in a Cross-Cultural Teaching Context: Pre-Service Chinese Language Teachers Undertaking Teaching Practicum in International Schools in Hong Kong

ERIC Educational Resources Information Center

Lai, Chun; Gu, Mingyue; Hu, Jingjing

2015-01-01

Legitimate teacher authority is fundamental to effective teaching, but is often a thorny issue that teachers need to grapple with when teaching in cross-cultural teaching contexts. By interviewing 18 pre-service Chinese language teachers on their understanding of legitimate teacher authority throughout teaching practicum at international schools…

Comparison of the safety-related physical and combustion properties of liquid hydrogen and liquid natural gas in the context of the SF-BREEZE high-speed fuel-cell ferry

DOE PAGES

Klebanoff, L. E.; Pratt, J. W.; LaFleur, C. B.

2016-11-25

Here, we review liquid hydrogen (LH 2) as a maritime vessel fuel, from descriptions of its fundamental properties to its practical application and safety aspects, in the context of the San Francisco Bay Renewable Energy Electric Vessel with Zero Emissions (SF-BREEZE) high-speed fuel-cell ferry. Since marine regulations have been formulated to cover liquid natural gas (LNG) as a primary propulsion fuel, we frame our examination of LH 2 as a comparison to LNG, for both maritime use in general, and the SF-BREEZE in particular. Due to weaker attractions between molecules, LH 2 is colder than LNG, and evaporates more easily.more » We describe the consequences of these physical differences for the size and duration of spills of the two cryogenic fuels. The classical flammability ranges are reviewed, with a focus on how fuel buoyancy modifies these combustion limits. We examine the conditions for direct fuel explosion (detonation) and contrast them with initiation of normal (laminar) combustion. Direct fuel detonation is not a credible accident scenario for the SF-BREEZE. For both fuels, we review experiments and theory elucidating the deflagration to detonation transition (DDT). LH 2 fires have a shorter duration than energy-equivalent LNG fires, and produce significantly less thermal radiation. The thermal (infrared) radiation from hydrogen fires is also strongly absorbed by humidity in the air. Hydrogen permeability is not a leak issue for practical hydrogen plumbing. We describe the chemistry of hydrogen and methane at iron surfaces, clarifying their impact on steel-based hydrogen storage and transport materials. These physical, chemical and combustion properties are pulled together in a comparison of how a LH 2 or LNG pool fire on the Top Deck of the SF-BREEZE might influence the structural integrity of the aluminum deck. Neither pool fire scenario leads to net heating of the aluminum decking. Overall, LH 2 and LNG are very similar in their physical and combustion

Comparison of the safety-related physical and combustion properties of liquid hydrogen and liquid natural gas in the context of the SF-BREEZE high-speed fuel-cell ferry

DOE Office of Scientific and Technical Information (OSTI.GOV)

Klebanoff, L. E.; Pratt, J. W.; LaFleur, C. B.

Here, we review liquid hydrogen (LH 2) as a maritime vessel fuel, from descriptions of its fundamental properties to its practical application and safety aspects, in the context of the San Francisco Bay Renewable Energy Electric Vessel with Zero Emissions (SF-BREEZE) high-speed fuel-cell ferry. Since marine regulations have been formulated to cover liquid natural gas (LNG) as a primary propulsion fuel, we frame our examination of LH 2 as a comparison to LNG, for both maritime use in general, and the SF-BREEZE in particular. Due to weaker attractions between molecules, LH 2 is colder than LNG, and evaporates more easily.more » We describe the consequences of these physical differences for the size and duration of spills of the two cryogenic fuels. The classical flammability ranges are reviewed, with a focus on how fuel buoyancy modifies these combustion limits. We examine the conditions for direct fuel explosion (detonation) and contrast them with initiation of normal (laminar) combustion. Direct fuel detonation is not a credible accident scenario for the SF-BREEZE. For both fuels, we review experiments and theory elucidating the deflagration to detonation transition (DDT). LH 2 fires have a shorter duration than energy-equivalent LNG fires, and produce significantly less thermal radiation. The thermal (infrared) radiation from hydrogen fires is also strongly absorbed by humidity in the air. Hydrogen permeability is not a leak issue for practical hydrogen plumbing. We describe the chemistry of hydrogen and methane at iron surfaces, clarifying their impact on steel-based hydrogen storage and transport materials. These physical, chemical and combustion properties are pulled together in a comparison of how a LH 2 or LNG pool fire on the Top Deck of the SF-BREEZE might influence the structural integrity of the aluminum deck. Neither pool fire scenario leads to net heating of the aluminum decking. Overall, LH 2 and LNG are very similar in their physical and combustion

Development of a Mobility Training Program for Young Adult Trainable Mentally Handicapped Clients at the Ray Graham Training Center. Maxi II Practicum Report.

ERIC Educational Resources Information Center

Jordan, Ellen M.

Provided is a practicum report on a travel training program initiated at the Ray Graham Training Center (Chicago, Illinois) for 40 trainable mentally handicapped young adults. The center is described in terms of the geographic area and clients served, staff roles, parent role, and curriculum. It is noted that a prime impetus for the development of…

Pre-Practicum Training in Professional Psychology to Close the Research-Practice Gap: Changing Attitudes Towards Evidence-Based Practice.

PubMed

Bearman, Sarah Kate; Wadkins, Melanie; Bailin, Abby; Doctoroff, Greta

2015-02-01

Despite the rapid proliferation of mental health interventions with proven benefit for youth, empirically supported interventions (ESIs) are underutilized in most service settings. Treatment outcome studies in these community-based settings suggest that the majority of youth do not show improvement, underscoring the importance of addressing the gap between research and practice. Clinician attitudes toward evidence-based practice (EBP) may limit the use of ESIs, and efforts to address these attitudes with post-graduate training pose significant challenges. Pre-practicum training in EBP may address these challenges by familiarizing students with the framework of EBP as well as with the current youth treatment evidence base and the theories and strategies of well-supported interventions. We describe a required EBP course within a professional psychology doctoral program. Forty-two students in two class cohorts completed a measure of attitudes toward EBP prior to the first class and after the final class lecture. Students were predominantly Caucasian women with bachelor's degrees. As expected, over the course of the class, student attitudes became significantly more favorable toward EBP. Students who had previously received a master's degree had more favorable attitudes prior to the class, and students with a prior bachelor's degree showed the greatest change in attitude. The results support the use of pre-practicum training in EBP to improve attitudes toward EBP, which may lead to use of effective practices with clients following training.

Pre-Practicum Training in Professional Psychology to Close the Research-Practice Gap: Changing Attitudes Towards Evidence-Based Practice

PubMed Central

Bearman, Sarah Kate; Wadkins, Melanie; Bailin, Abby; Doctoroff, Greta

2014-01-01

Despite the rapid proliferation of mental health interventions with proven benefit for youth, empirically supported interventions (ESIs) are underutilized in most service settings. Treatment outcome studies in these community-based settings suggest that the majority of youth do not show improvement, underscoring the importance of addressing the gap between research and practice. Clinician attitudes toward evidence-based practice (EBP) may limit the use of ESIs, and efforts to address these attitudes with post-graduate training pose significant challenges. Pre-practicum training in EBP may address these challenges by familiarizing students with the framework of EBP as well as with the current youth treatment evidence base and the theories and strategies of well-supported interventions. We describe a required EBP course within a professional psychology doctoral program. Forty-two students in two class cohorts completed a measure of attitudes toward EBP prior to the first class and after the final class lecture. Students were predominantly Caucasian women with bachelor's degrees. As expected, over the course of the class, student attitudes became significantly more favorable toward EBP. Students who had previously received a master's degree had more favorable attitudes prior to the class, and students with a prior bachelor's degree showed the greatest change in attitude. The results support the use of pre-practicum training in EBP to improve attitudes toward EBP, which may lead to use of effective practices with clients following training. PMID:25745525

Modelling study of sea breezes in a complex coastal environment

NASA Astrophysics Data System (ADS)

Cai, X.-M.; Steyn, D. G.

This study investigates a mesoscale modelling of sea breezes blowing from a narrow strait into the lower Fraser valley (LFV), British Columbia, Canada, during the period of 17-20 July, 1985. Without a nudging scheme in the inner grid, the CSU-RAMS model produces satisfactory wind and temperature fields during the daytime. In comparison with observation, the agreement indices for surface wind and temperature during daytime reach about 0.6 and 0.95, respectively, while the agreement indices drop to 0.4 at night. In the vertical, profiles of modelled wind and temperature generally agree with tethersonde data collected on 17 and 19 July. The study demonstrates that in late afternoon, the model does not capture the advection of an elevated warm layer which originated from land surfaces outside of the inner grid. Mixed layer depth (MLD) is calculated from model output of turbulent kinetic energy field. Comparison of MLD results with observation shows that the method generates a reliable MLD during the daytime, and that accurate estimates of MLD near the coast require the correct simulation of wind conditions over the sea. The study has shown that for a complex coast environment like the LFV, a reliable modelling study depends not only on local surface fluxes but also on elevated layers transported from remote land surfaces. This dependence is especially important when local forcings are weak, for example, during late afternoon and at night.

Creating innovative clinical nurse leader practicum experiences through academic and practice partnerships.

PubMed

Jukkala, Angela; Greenwood, Rebecca; Motes, Terry; Block, Velinda

2013-01-01

The new Clinical Nurse Leader (CNL) nursing role was developed to meet the complex health care needs of patients, families, and health care systems. This article describes the process used by nurse leaders at the University of Alabama at Birmingham School of Nursing and Hospital to develop Model C CNL practicum courses, recruit and prepare clinical preceptors, prepare clinical microsystems for CNL students, and develop additional practice partnerships throughout the region. MANAGEMENT AND OUTCOME: Critical to the success of the CNL role is a dynamic partnership between academic and practice leaders.The partnership allows faculty to develop curricula that are relevant and responsive to the rapidly changing health care system. Clinical leaders become more aware of trends and issues in nursing education. Continued growth and success of the CNL role is largely dependent on the ability of faculty and practice partners to collaborate on innovative educational programs and models of care delivery.

Observed and simulated features of the phases of the sea-breeze in the island of Mallorca

NASA Astrophysics Data System (ADS)

Jimenez, Maria A.; Cuxart, Joan; Simó, Gemma; Wrenger, Burkhard; Martinez-Villagrasa, Daniel; Guijarro, Jose A.; Telisman-Prtenjak, Maja; Lopez, Alvaro; Picos, Rodrigo

2016-04-01

In order to better understand the diurnal cycle of the Sea-Breeze (SB) in the island of Mallorca, during September 2013 and June 2014 two experimental field campaigns have been conducted in the Campos basin (at the south side). A total of 6 IOPs (clear skies and weak pressure gradient conditions) are analysed using observations taken close to the coastline (about 900 m inland) that consist on a surface portable station (equipped with a temperature and humidity probe, and one 2-D and 3-D sonic anemometers), a captive balloon (temperature and humidity) and a multicopter (temperature and humidity). Besides, observations from automatic weather stations of the AEMET network are taken as well as satellite-derived surface temperatures that together with the model outputs from high-resolution mesoscale simulations are used to better understand the organization of the flow at lower levels. With the combined inspection of observations and model results it is found that during the previous phase (after sunrise) land-breeze conditions were present and the sensible heat flux turned to positive meanwhile the turbulence started. In the preparatory phase (about 3 hours after sunrise) the wind close to the coast started to veer progressively towards the SB direction. As soon as the SB was initiated (about 5 hours after sunrise), the SB front progressed to the inland direction reaching a mature phase starting at noon. Afterwards, the SB decaying starts and close to sunset the wind speed was close to zero and veered towards the land to sea direction. During the campaign all phases were measured with special emphasis to the morning transition (from LB to SB) and the evening transition (from SB to LB) because of the strong wind shear (turbulence) reported during the mature phase. It is found that for all the different phases the model is able to capture the organization of the flow at lower levels although it experiences some difficulties in reproducing the thermal profile during the

Warm Breeze due to Charge Exchange Collisions Between Neutral He Atoms and He+ Ions in the Outer Heliosheath.

NASA Astrophysics Data System (ADS)

Kubiak, M. A.; Bzowski, M.; Czechowski, A.; Grygorczuk, J.

2017-12-01

We simulated the signal due to neutral He atoms, observed by Interstellar Boundary Explorer (IBEX), assuming that charge exchange collisions between neutral He atoms and He+ ions operate everywhere between the heliopause and a distant source region in the local interstellar cloud (LIC). We chose the limiting distance of calculations at 5000 AU, where the neutral and charged components are in thermal equilibrium. From that distance we integrated the signal for test particles that we know they reach the IBEX detector, calculating for each particle the balance of losses and gains in the LIC, the ionization losses inside the HP, and the distribution function at 5000 AU. The resulting statistical weights were integrated over speed, inflow direction, collimator transmission, observation times, and IBEX spin angle bins to simulate the count rate actually observed by IBEX. We simulated several test cases of the plasma flow within the outer heliosheath and investigated the signal generation for plasma flows both in the presence and in the absence of the interstellar magnetic field. We found that a signal in the portion of IBEX data identified as due to the Warm Breeze does not arise when a homogeneous plasma flow in front of the heliopause is assumed. However, it appears immediately when any reasonable disturbance in the plasma flow due to the presence of the heliosphere is assumed. We obtained a good qualitative agreement between the data and the simulations for a model flow with the velocity vector of the unperturbed gas and the direction and intensity of magnetic field adopted from recent determinations. We conclude that direct-sampling observations of neutral He atoms at 1 AU from the Sun are a sensitive tool for investigating the flow of interstellar matter in the outer heliosheath; the Warm Breeze is indeed the secondary population of interstellar helium, as it was hypothesized earlier; the WB signal is consistent with that predicted by comet-like models of the

Guiding Development Based Approach Practicum Vertebrates Taxonomy Scientific Study Program for Students of Biology Education

NASA Astrophysics Data System (ADS)

Arieska, M.; Syamsurizal, S.; Sumarmin, R.

2018-04-01

Students having difficulty in identifying and describing the vertebrate animals as well as less skilled in science process as practical. Increased expertise in scientific skills, one of which is through practical activities using practical guidance based on scientific approach. This study aims to produce practical guidance vertebrate taxonomy for biology education students PGRI STKIP West Sumatra valid. This study uses a model of Plomp development consisting of three phases: the initial investigation, floating or prototype stage, and the stage of assessment. Data collection instruments used in this study is a validation sheet guiding practicum. Data were analyzed descriptively based on data obtained from the field. The result of the development of practical guidance vertebrate taxonomic validity value of 3.22 is obtained with very valid category. Research and development has produced a practical guide based vertebrate taxonomic scientific approach very valid.

Surf Zone Sediment Size Variation, Morphodynamics, and Hydrodynamics During Sea/Land Breeze and El-Norte Storm in Sisal, Yucatan, Mexico

NASA Astrophysics Data System (ADS)

Alrushaid, T.; Figlus, J.; Torres-Freyermuth, A.; Puleo, J. A.; Dellapenna, T. M.

2016-02-01

Coastlines around the world are under ever-increasing pressure due to population trends, commerce, and geophysical processes like tropical storms and erosion. This multi-institutional field campaign was conducted to improve our understanding of complex nearshore processes under varying forcing conditions on a microtidal, sandy beach located in Sisal, Yucatan from 3/27 to 4/12/2014. Hydrodynamics, morphodynamics, and textural variability were investigated during: (1) a cold front event (referred to as El-Norte); (2) land breeze (LB); and (3) sea breeze (SB). The instrumentation layout included three surf/swash zone cross-shore transects where water elevation, suspended sediment concentration, bed load, and current velocities were measured, as well as several offshore ADCP for hydrodynamic measurements. TKE, τb, ɛ and were estimated using the data obtained from surf zone ADV. In addition, Hs and Tsin the surf zone were computed using measurements from ADV pressure sensors, while a separate pressure transducer was used to obtain water free-surface elevation within the swash zone. During SB cycles the study area experienced wind velocities reaching up to 12ms-1, and 15ms-1 during El-Norte. Elevated wind stress during El-Norte resulted in Hs of 1.5m and 0.6m in water depths of 10m and 0.4m, respectively. Surface sediment grab samples during SB/LB cycles showed that the swash zone had a moderately well sorted distribution with a mean grain size of 0.5mm, while poor sorting and a mean grain size of 0.7mm were found during El-Norte. Additionally, measured bathymetry data showed evidence for offshore sandbar migration during strong offshore currents (0.4ms-1) during El-Norte, while onshore sandbar migration was evident during SB/LB periods (0.3ms-1 and 0.1ms-1, respectively). This study highlights how different weather forcing conditions affect hydrodynamics, morphodynamics, and textural variability on a sandy beach. Aside from furthering our knowledge on these complex

A scale model wind tunnel study of dispersion in the Cleveland area. Laboratory simulation of lake breeze effects on diffusion from ground level emissions

NASA Technical Reports Server (NTRS)

Hoydysh, W. G.

1974-01-01

A wind tunnel simulation of the diffusion patterns in a sea breeze was attempted. The results indicate that the low level onshore flow was well simulated for neutral, stable, unstable, and elevated inversion conditions. Velocity, turbulence, shear stress, and temperature data were taken, and the spread of emissions from ground level sources was investigated. Comparison is made with theoretical predictions by E. Inoue and with the open, homogeneous plane field results of Pasquill. Agreement with the predictions by Inoue is good, and the comparison with Pasquill's results shows that the wind tunnel flows are shifted two categories towards more stable. The discrepancy may be explained as a matter of averaging time.

Conceptual design of modular fixture for frame welding and drilling process integration case study: Student chair in UNS industrial engineering integrated practicum

NASA Astrophysics Data System (ADS)

Darmawan, Tofiq Dwiki; Priadythama, Ilham; Herdiman, Lobes

2018-02-01

Welding and drilling are main processes of making chair frame from metal material. Commonly, chair frame construction includes many arcs which bring difficulties for its welding and drilling process. In UNS industrial engineering integrated practicum there are welding fixtures which use to fixing frame component position for welding purpose. In order to achieve exact holes position for assembling purpose, manual drilling processes were conducted after the frame was joined. Unfortunately, after it was welded the frame material become hard and increase drilling tools wear rate as well as reduce holes position accuracy. The previous welding fixture was not equipped with clamping system and cannot accommodate drilling process. To solve this problem, our idea is to reorder the drilling process so that it can be execute before welding. Thus, this research aims to propose conceptual design of modular fixture which can integrate welding and drilling process. We used Generic Product Development Process to address the design concept. We collected design requirements from 3 source, jig and fixture theoretical concepts, user requirements, and clamping part standards. From 2 alternatives fixture tables, we propose the first which equipped with mounting slots instead of holes. We test the concept by building a full sized prototype and test its works by conducting welding and drilling of a student chair frame. Result from the welding and drilling trials showed that the holes are on precise position after welding. Based on this result, we conclude that the concept can be a consideration for application in UNS Industrial Engineering Integrated Practicum.

The use of fractionated fly ash of thermal power plants as binder for production of briquettes of coke breeze and dust

NASA Astrophysics Data System (ADS)

Temnikova, E. Yu; Bogomolov, A. R.; Lapin, A. A.

2017-11-01

In this paper, we propose to use the slag and ash material of thermal power plants (TPP) operating on pulverized coal fuel. The elemental and chemical composition of fly ash of five Kuzbass thermal power plants differs insignificantly from the composition of the mineral part of coking coal because coke production uses a charge, whose composition defines the main task: obtaining coke with the required parameters for production of iron and steel. These indicators are as follows: CRI reactivity and strength of the coke residue after reaction with CO2 - CSR. The chemical composition of fly ash of thermal power plants and microsilica with bulk density of 0.3-0.6 t/m3 generated at production of ferroalloys was compared. Fly ash and microsilica are the valuable raw material for production of mineral binder in manufacturing coke breeze briquettes (fraction of 2-10 mm) and dust (0-200 μm), generated in large quantities during coking (up to 40wt%). It is shown that this binder is necessary for production of smokeless briquettes with low reactivity, high strength and cost, demanded for production of cupola iron and melting the silicate materials, basaltic rocks in low-shaft furnaces. It is determined that microsilica contains up to 90% of silicon oxide, and fly ash contains up to 60% of silicon oxide and aluminum oxide of up to 20%. On average, the rest of fly ash composition consists of basic oxides. According to calculation by the VUKHIN formula, the basicity index of briquette changes significantly, when fly ash is introduced into briquette raw material component as a binder. The technology of coke briquette production on the basis of the non-magnetic fraction of TPP fly ash in the ratio from 3.5:1 to 4.5:1 (coke breeze : coke dust) with the addition of the binder component to 10% is proposed. The produced briquettes meet the requirements by CRI and require further study on CSR requirements.

3D Structures of the Sea-Breeze Front in Dual-Doppler Lidar Analysis and a State-of-the-Art Modeling System

NASA Astrophysics Data System (ADS)

Chen, G.; Iwai, H.; Seko, H.; Saito, K. K.; Sha, W.; Iwasaki, T.

2017-12-01

Sea breeze occurs at coastal regions around the world, with great impacts on the weather and air quality. Observations and forecasts of the fine-scale structures and local impacts of sea-breeze front (SBF) are a challenge. Three-dimensional structures of a quasi-stationary SBF were observed by dual-Doppler lidar over Sendai Airport in June 2007. Using a state-of-the-art local prediction system in which a computational fluid dynamics model is nested to a mesoscale model with data assimilation, we perform a realistic simulation of the observed SBF structures at 10-m resolution. Numerical simulations reproduce the detailed features of the SBF, such as frontal lobes/clefts, intense updrafts, rear downdrafts, and Kelvin-Helmholtz billows, consistent with lidar observations. Several localized maxima of updrafts occur at the active SBF lobes with ascending marine air mass and adjacent windward sides, where the ambient warm flows encounter a steep front face and penetrate SBF aloft. Strong downdrafts of marine cool air dominate at the SBF rear where they trap a high concentration of air pollutants. These features are regularly activated by the arc-shaped gravity currents at a horizontal scale of several kilometers and a period of 30 minutes. They are also influenced by the coastal buildings and strongly regulate the spatio-temporal variations of local winds near surface. The findings suggest that a novel full-scale nested prediction system has potential for forecasting coastal weather and environment at high precision, which are valuable for aviation safety, marine activities, and air quality monitoring. AcknowledgmentsThis study was supported by the Strategic Programs for Innovative Research (SPIRE) funded by the Japan Ministry of Education, Culture, Sports, Science and Technology (MEXT). The numerical calculations were performed using the K computer at RIKEN Advanced Institute for Computational Science (Proposal numbers hp130012 and hp140220). The observational data were

Student Needs to Practicum Guidance in Physiology of Animals Based on Guided Inquiry

NASA Astrophysics Data System (ADS)

Widiana, R.; Susanti, S.; Susanti, D.

2017-09-01

The achievement of the subject of animal physiology requires that the students actively and creatively find their knowledge independently in understanding the concepts, theories, physiological processes, decompose, assemble, compare and modify physiological processes in relation to the fluctuation of environmental factors through practicum activities. The achievement of this lesson has not been fully realized because the learning resources used can’t guide, direct and make the independent students achieve their learning achievement and the practical handbook used has not been able to lead the students active and creative in finding their own knowledge. The practical handbook used so far consists only of the introduction of materials, work steps and questions. For that, we need to develop guided inquiry guide based on the needs of students. Objectives this study produces a practical handbook that fits the needs of the students. The research was done by using 4-D models and limited to define stage that is student requirement analysis. Data obtained from the questionnaire and analysed descriptively. The questionnaire obtained an average of 88.16%. So the needs of students will guide guided inquiry based inquiry both to be developed.

Students' Satisfaction with an Undergraduate Primary Education Teaching Practicum Design on Developing Technological, Pedagogical and Mathematical Knowledge

NASA Astrophysics Data System (ADS)

Doukakis, Spyros; Koilias, Christos; Chionidou-Moskofoglou, Maria

During the 2008-2009 spring semester, 25 fourth-year undergraduate primary teachers attended the compulsory course "Teaching Mathematics-Practicum Phase". The course was organised so as to incorporate ICT and special mathematical scenarios in the teaching approaches of undergraduate primary teachers. This article presents course satisfaction of participants as found in the research study. A set of powerful ordinal regression methods has been applied on a survey database. The most important results focus on the determination of the course's weak and strong points, according to the MUSA methodology. The results show a high satisfaction level from the course. The global satisfaction level reaches 98% whereas partial (per criterion) satisfaction levels range from 90% to 97%, the lowest rate corresponding to the theoretical component of the course. The findings raise a number of research questions regarding ICT integration in undergraduate primary teachers' teaching practice.

Assisting undergraduate nursing students to learn evidence-based practice through self-directed learning and workshop strategies during clinical practicum.

PubMed

Zhang, Qi; Zeng, Tieying; Chen, Ying; Li, Xiaopan

2012-07-01

To equip undergraduate nursing students with basic knowledge and skills and foster positive attitudes toward evidence-based practice (EBP), a pilot learning program during their clinical practicum was developed in a teaching hospital in China. This article describes the specific learning process through which self-directed learning and workshop strategies were used, and a pre- and post-intervention survey were conducted to evaluate the effectiveness of the learning strategies. The findings show a significant improvement in their perceptions of EBP knowledge, attitudes and beliefs, and behavior levels. Beginning competencies in EBP were achieved. Participants reported great satisfaction and have found this program helpful in promoting their analytical and problem-solving abilities, independent learning ability, and cooperative and communication abilities as well. Copyright © 2011 Elsevier Ltd. All rights reserved.

The West Virginia Occupational Safety and Health Initiative: practicum training for a new marketplace.

PubMed

Meyer, J D; Becker, P E; Stockdale, T; Ducatman, A M

1999-05-01

Occupational medicine practice has experienced a shift from larger corporate medical departments to organizations providing services for a variety of industries. Specific training needs will accompany this shift in practice patterns; these may differ from those developed in the traditional industrial or corporate medical department setting. The West Virginia Occupational Health and Safety Initiative involves occupational medicine residents in consultation to a variety of small industries and businesses. It uses the expertise of occupational physicians, health and safety extension faculty, and faculty in engineering and industrial hygiene. Residents participate in multidisciplinary evaluations of worksites, and develop competencies in team-building, workplace health and safety evaluation, and occupational medical consulting. Specific competencies that address requirements for practicum training are used to measure the trainee's acquisition of knowledge and skills. Particular attention is paid to the acquisition of group problem-solving expertise, skills relevant to the current market in practice opportunities, and the specific career interests of the resident physician. Preliminary evaluation indicates the usefulness of training in evaluation of diverse industries and worksites. We offer this program as a training model that can prepare residents for the challenges of a changing marketplace for occupational health and safety services.

Implementation of interprofessional learning activities in a professional practicum: The emerging role of technology.

PubMed

Brault, Isabelle; Therriault, Pierre-Yves; St-Denis, Louise; Lebel, Paule

2015-01-01

To prepare future healthcare professionals to collaborate effectively, many universities have developed interprofessional education programs (IPE). Till date, these programs have been mostly courses or clinical simulation experiences. Few attempts have been made to pursue IPE in healthcare clinical settings. This article presents the results of a pilot project in which interprofessional learning activities (ILAs) were implemented during students' professional practicum and discusses the actual and potential use of informatics in the ILA implementation. We conducted a pilot study in four healthcare settings. Our analysis is based on focus group interviews with trainees, clinical supervisors, ILA coordinators, and education managers. Overall, ILAs led to better clarification of roles and understanding of each professional's specific expertise. Informatics was helpful for developing a common language about IPE between trainees and healthcare professionals; opportunities for future application of informatics were noted. Our results support the relevance of ILAs and the value of promoting professional exchanges between students of different professions, both in academia and in the clinical setting. Informatics appears to offer opportunities for networking among students from different professions and for team members' professional development. The use of technology facilitated communication among the participants.

An Internship May Not Be Enough: Enhancing Bioscience Industry Job Readiness through Practicum Experiences.

PubMed

Cramer, Jason M; Hamilton, Paul T

2017-04-01

In contrast to the narrowing of options in academic careers, the bioscience industry offers robust employment opportunities for STEM-trained workers, especially those who display both scientific and business talent. Unfortunately, traditional science programs typically lack curricular features that develop this type of worker. The North Carolina State University Master of Microbial Biotechnology (MMB) program facilitates industry-specific experiential learning to fill this training gap. Similar programs often rely on a single industry internship to provide students relevant work experience, but completion of one internship might not suffice to position students for employment in a highly competitive job market. The MMB program requires students to complete an internship and three practicum projects in an industry setting, to promote development of key skills in a variety of areas, to build confidence in the ability to perform initial job duties, and to establish a more extensive work history in industry. In this Perspective we discuss an unmet need in undergraduate and graduate STEM education that can be filled by incorporating a similar set of industry-specific work experiences for students who desire to transition from academe into the life science industry.

Intersections of lung progenitor cells, lung disease and lung cancer.

PubMed

Kim, Carla F

2017-06-30

The use of stem cell biology approaches to study adult lung progenitor cells and lung cancer has brought a variety of new techniques to the field of lung biology and has elucidated new pathways that may be therapeutic targets in lung cancer. Recent results have begun to identify the ways in which different cell populations interact to regulate progenitor activity, and this has implications for the interventions that are possible in cancer and in a variety of lung diseases. Today's better understanding of the mechanisms that regulate lung progenitor cell self-renewal and differentiation, including understanding how multiple epigenetic factors affect lung injury repair, holds the promise for future better treatments for lung cancer and for optimising the response to therapy in lung cancer. Working between platforms in sophisticated organoid culture techniques, genetically engineered mouse models of injury and cancer, and human cell lines and specimens, lung progenitor cell studies can begin with basic biology, progress to translational research and finally lead to the beginnings of clinical trials. Copyright ©ERS 2017.

Lung transplantation and interstitial lung disease.

PubMed

Alalawi, Raed; Whelan, Timothy; Bajwa, Ravinder S; Hodges, Tony N

2005-09-01

Interstitial lung disease includes a heterogeneous group of disorders that leads to respiratory insufficiency and death in a significant number of patients. Lung transplantation is a therapeutic option in select candidates. The indications, transplant procedure options, and outcomes continue to evolve. Various recipient comorbidities influence the choice of procedure in patients with interstitial lung disease. Single lung transplants are used as the procedure of choice and bilateral transplants are reserved for patients with suppurative lung disease and patients with pulmonary hypertension. Issues unique to patients with interstitial lung disease affect the morbidity, mortality and recurrence of the disease. Lung transplantation is an effective therapy for respiratory failure in interstitial lung disease with survival following transplant being similar to that achieved in transplant recipients with other diseases.

Lung Cancer and Lung Transplantation.

PubMed

Brand, Timothy; Haithcock, Benjamin

2018-02-01

Lung transplantation remains a viable option for patients with endstage pulmonary disease. Despite removing the affected organ and replacing both lungs, the risk of lung malignancies still exists. Regardless of the mode of entry, lung cancer affects the prognosis in these patients and diligence is required. Copyright © 2017 Elsevier Inc. All rights reserved.

The Lung Microbiome After Lung Transplantation

PubMed Central

Becker, Julia B.; Poroyko, Valeriy

2014-01-01

Summary Lung transplantation survival remains significantly impacted by infections and the development of chronic rejection manifesting as bronchiolitis obliterans syndrome (BOS). Traditional microbiologic data has provided insight into the role of infections in BOS. Now, new non-culture-based techniques have been developed to characterize the entire population of microbes resident on the surfaces of the body, also known as the human microbiome. Early studies have identified that lung transplant patients have a different lung microbiome and have demonstrated the important finding that the transplant lung microbiome changes over time. Furthermore, both unique bacterial populations and longitudinal changes in the lung microbiome have now been suggested to play a role in the development of BOS. In the future, this technology will need to be combined with functional assays and assessment of the immune responses in the lung to help further explain the microbiome’s role in the failing lung allograft. PMID:24601662

Study of the thermal internal boundary layer during sea-breeze events in the complex coastal area of Marseille

NASA Astrophysics Data System (ADS)

Calmet, Isabelle; Mestayer, Patrice

2016-02-01

A revisit of two sea-breeze episodes is presented, based on higher spatial resolution large eddy simulations (LES) of the lower atmosphere over the coastal area of Marseille and measurements obtained during the June 2001 experimental campaign UBL-ESCOMPTE. The focus is on the development of thermal internal boundary layers (TIBL) over a complex topography: the dynamic and thermal mechanisms that contribute to the TIBL growth and its further degeneration into a convective mixed layer, the respective influences of the coast shape, the large-scale flow above and the local low-level slope flows. The high-resolution LES permits exploring the potential temperature and turbulent kinetic energy fields in relation with the evolution of TIBL depth and heat fluxes along representative streamlines. Several theoretical TIBL depth models are further compared to the LES-deduced inversion height and other parameters, leading to a discussion of the relationships between the values of these parameters, the respective influences of the governing physical phenomena, and the TIBL behaviour. A threshold value of 0.35 is proposed for the friction velocity to convective velocity scale ratio u */ w * between the two regimes where the TIBL is either dominated by dynamical kinetic energy production or controlled by buoyancy.

Technetium-fibrinogen lung scanning in canine lung contusion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Geller, E.; Khaw, B.A.; Strauss, H.W.

1984-07-01

To detect experimentally induced acute lung contusion in anesthetized dogs, serial radionuclide images of the lung were recorded following intravenous infusion of 99mTc-labelled human fibrinogen (Tc-HF). The accumulation of Tc-HF in canine lungs was serially quantitated for up to 20 hours after lung contusion. A contusion (number1) was produced in one lung, Tc-HF was injected IV after 15 minutes, and 75 minutes later a contralateral lung contusion (number2) was produced in a series of 14 dogs. At autopsy the excised lungs were scanned, sectioned, and counted for radioactivity. Radiolabelled fibrinogen accumulated within 2-4 minutes of contusion number2 and remained stablemore » over the next 20 hours in 14 dogs; contusion number1 was barely visible in four dogs. Lung Tc-HF activity in the central region of contusion number2 remained sixfold higher than in normal lung tissue. These data suggest that following lung contusion, fibrinogen deposition occurs rapidly and remains stable over a 20-hour interval of observation.« less

Lung Transplantation

MedlinePlus

A lung transplant removes a person's diseased lung and replaces it with a healthy one. The healthy lung comes from ... lung during a transplant. Other people get two. Lung transplants are used for people who are likely to ...

Lung cancer

MedlinePlus

Cancer - lung ... lung cancer than of breast, colon, and prostate cancers combined. Lung cancer is more common in older adults. It ... Horn L, Eisenberg R, Gius D, et al. Cancer of the lung: non-small cell lung cancer and small cell ...

Lung metastases

MedlinePlus

Metastases to the lung; Metastatic cancer to the lung; Lung cancer - metastases ... Metastatic tumors in the lungs are cancers that developed at other places in the body (or other parts of the lungs). They then spread through the bloodstream or lymphatic ...

Regeneration of the lung: Lung stem cells and the development of lung mimicking devices.

PubMed

Schilders, Kim A A; Eenjes, Evelien; van Riet, Sander; Poot, André A; Stamatialis, Dimitrios; Truckenmüller, Roman; Hiemstra, Pieter S; Rottier, Robbert J

2016-04-23

Inspired by the increasing burden of lung associated diseases in society and an growing demand to accommodate patients, great efforts by the scientific community produce an increasing stream of data that are focused on delineating the basic principles of lung development and growth, as well as understanding the biomechanical properties to build artificial lung devices. In addition, the continuing efforts to better define the disease origin, progression and pathology by basic scientists and clinicians contributes to insights in the basic principles of lung biology. However, the use of different model systems, experimental approaches and readout systems may generate somewhat conflicting or contradictory results. In an effort to summarize the latest developments in the lung epithelial stem cell biology, we provide an overview of the current status of the field. We first describe the different stem cells, or progenitor cells, residing in the homeostatic lung. Next, we focus on the plasticity of the different cell types upon several injury-induced activation or repair models, and highlight the regenerative capacity of lung cells. Lastly, we summarize the generation of lung mimics, such as air-liquid interface cultures, organoids and lung on a chip, that are required to test emerging hypotheses. Moreover, the increasing collaboration between distinct specializations will contribute to the eventual development of an artificial lung device capable of assisting reduced lung function and capacity in human patients.

Lung dendritic cells imprint T cell lung homing and promote lung immunity through the chemokine receptor CCR4

PubMed Central

Strassner, James P.

2013-01-01

T cell trafficking into the lung is critical for lung immunity, but the mechanisms that mediate T cell lung homing are not well understood. Here, we show that lung dendritic cells (DCs) imprint T cell lung homing, as lung DC–activated T cells traffic more efficiently into the lung in response to inhaled antigen and at homeostasis compared with T cells activated by DCs from other tissues. Consequently, lung DC–imprinted T cells protect against influenza more effectively than do gut and skin DC–imprinted T cells. Lung DCs imprint the expression of CCR4 on T cells, and CCR4 contributes to T cell lung imprinting. Lung DC–activated, CCR4-deficient T cells fail to traffic into the lung as efficiently and to protect against influenza as effectively as lung DC–activated, CCR4-sufficient T cells. Thus, lung DCs imprint T cell lung homing and promote lung immunity in part through CCR4. PMID:23960189

Interplay between the lung microbiome and lung cancer.

PubMed

Mao, Qixing; Jiang, Feng; Yin, Rong; Wang, Jie; Xia, Wenjie; Dong, Gaochao; Ma, Weidong; Yang, Yao; Xu, Lin; Hu, Jianzhong

2018-02-28

The human microbiome confers benefits or disease susceptibility to the human body through multiple pathways. Disruption of the symbiotic balance of the human microbiome is commonly found in systematic diseases such as diabetes, obesity, and chronic gastric diseases. Emerging evidence has suggested that dysbiosis of the microbiota may also play vital roles in carcinogenesis at multiple levels, e.g., by affecting metabolic, inflammatory, or immune pathways. Although the impact of the gut microbiome on the digestive cancer has been widely explored, few studies have investigated the interplay between the microbiome and lung cancer. Some recent studies have shown that certain microbes and microbiota dysbiosis are correlated with development of lung cancer. In this mini-review, we briefly summarize current research findings describing the relationship between the lung microbiome and lung cancer. We further discuss the potential mechanisms through which the lung microbiome may play a role in lung carcinogenesis and impact lung cancer treatment. A better knowledge of the interplay between the lung microbiome and lung cancer may promote the development of innovative strategies for early prevention and personalized treatment in lung cancer. Copyright © 2017 Elsevier B.V. All rights reserved.

Bringing a novel to practice: An interpretive study of reading a novel in an undergraduate nursing practicum course.

PubMed

McCaffrey, Graham; Venturato, Lorraine; Patterson, J David; Langille, Jennifer; Jackson, Roberta; Rosenal, Tom

2017-05-01

Novels are one humanities resource available to educators in health disciplines to support student reflection on their own professional practice and therapeutic relationships with patients. An interdisciplinary team, including nurses, a physician, and an English instructor, carried out an interpretive study of the use of a novel by clinical nursing instructors in an undergraduate practicum course. Students placed in assisted living or long term care facilities for the elderly were expected to read a contemporary work, Exit Lines, by Joan Barfoot, which is set in a comparable facility. The objective was to increase understanding of the meanings that participants ascribed to the novel reading exercise in relation to their development as student nurses. By using a hermeneutic approach, we used dialogue throughout the study to elicit perspectives among participants and the interdisciplinary research team. Major themes that emerged included the students' tacit awareness of epistemological plurality in nursing, and the consequent importance of cultivating a capacity to move thoughtfully between different points of view and ways of knowing. Copyright © 2017 Elsevier Ltd. All rights reserved.

[Lung transplantation.].

PubMed

Guðmundsson, G

2000-09-01

Lung transplantation is an option in the treatment of end stage lung diseases, excluding lung cancer, that lead to short life expectancy and poor quality of life. Now they are mostly limited by shortage of donor organs and longterm complications. They are used for various lung diseases such as pulmonary vascular diseases, fibrosing diseases, chronic obstructive pulmonary diseases and diseases that cause chronic infections. Depending on the indication it is possible to perform heart and lung transplantation, single lung or double lung transplantation.Indications, contraindications, surgical methods, immunosuppression, complications and outcomes will be discussed. Survival is not as good as for other solid organ transplantation. Measurement of pulmonary function and quality of life improve with lung transplantation. Bronchiolitis obliterans is the most common complication and is the most limiting factor. A few Icelanders have undergone lung transplantation, most of them in Gothenburg, Sweden. The future of lung transplantation depends on limiting the incidence of bronchiolitis obliterans and finding more organ donors.

Comprehensive evaluation of lung allograft function in infants after lung and heart-lung transplantation.

PubMed

Hayes, Don; Naguib, Aymen; Kirkby, Stephen; Galantowicz, Mark; McConnell, Patrick I; Baker, Peter B; Kopp, Benjamin T; Lloyd, Eric A; Astor, Todd L

2014-05-01

Limited data exist on methods to evaluate allograft function in infant recipients of lung and heart-lung transplants. At our institution, we developed a procedural protocol in coordination with pediatric anesthesia where infants were sedated to perform infant pulmonary function testing, computed tomography imaging of the chest, and flexible fiberoptic bronchoscopy with transbronchial biopsies. A retrospective review was performed of children aged younger than 1 year who underwent lung or heart-lung transplantation at our institution to assess the effect of this procedural protocol in the evaluation of infant lung allografts. Since 2005, 5 infants have undergone thoracic transplantation (3 heart-lung, 2 lung). At time of transplant, the mean ± standard deviation age was 7.2 ± 2.8 months (range, 3-11 months). Of 24 procedural sessions performed to evaluate lung allografts, 83% (20 of 24) were considered surveillance where the patients were completely asymptomatic. Of the surveillance procedures, 80% were performed as an outpatient, whereas 20% were done as inpatients during the lung or heart-lung transplant post-operative period before discharge home. Sedation was performed with propofol alone (23 of 24) or in addition to ketamine (1 of 24) infusion; mean sedation time was 141 ± 39 minutes (range, 70-214) minutes. Of the 16 outpatient procedures, patients were discharged after 14 (88%) on the same day, and after 2 (12%) were admitted for observation, with 1 being due to transportation issues and the other due to fever during the observation period. A comprehensive procedural protocol to evaluate allograft function in infant lung and heart-lung transplant recipients was performed safely as an outpatient. Copyright © 2014 International Society for Heart and Lung Transplantation. Published by Elsevier Inc. All rights reserved.

Lung cancer in patients with lung transplants.

PubMed

Espinosa, D; Baamonde, C; Illana, J; Arango, E; Carrasco, G; Moreno, P; Algar, F J; Alvarez, A; Cerezo, F; Santos, F; Vaquero, J M; Redel, J; Salvatierra, A

2012-09-01

The aim of our study was to describe the incidence of lung cancer in patients after lung transplantation (LT). We performed an observational, retrospective, descriptive study based on data from 340 patients undergoing lung transplantation between October 1993 and December 2010. We collected data about the donors, recipients, intra- and postoperative periods, and survivals. We identified 9 (2.6%) patients who developed lung cancer after LT. Their average age was 56 ± 9.3 years (range, 18-63). All cases were men with 8/9 (88.8%) having received a single lung transplant. All cancers developed in the native lung. The indications for transplantation were: emphysema type chronic obstructive pulmonary disease (COPD; n = 5), idiopathic pulmonary fibrosis (n = 3), or cystic fibrosis (n = 1); 77% of them were former smokers. All of the COPD patient were affected. The interval from transplantation to diagnosis was 53.3 ± 12 months (range 24-86). Survival after cancer diagnosis was 49.3 ± 6.3 (range = 0-180) months. LT was associated with a relatively high incidence of lung cancer, particularly in the native lung. In our series, lung cancer was related more to patients with emphysema-type COPD and a history of smoking. We believe that these patients should be closely followed to establish the diagnosis and apply early treatment. Copyright © 2012 Elsevier Inc. All rights reserved.

LungMAP: The Molecular Atlas of Lung Development Program

PubMed Central

Ardini-Poleske, Maryanne E.; Ansong, Charles; Carson, James P.; Corley, Richard A.; Deutsch, Gail H.; Hagood, James S.; Kaminski, Naftali; Mariani, Thomas J.; Potter, Steven S.; Pryhuber, Gloria S.; Warburton, David; Whitsett, Jeffrey A.; Palmer, Scott M.; Ambalavanan, Namasivayam

2017-01-01

The National Heart, Lung, and Blood Institute is funding an effort to create a molecular atlas of the developing lung (LungMAP) to serve as a research resource and public education tool. The lung is a complex organ with lengthy development time driven by interactive gene networks and dynamic cross talk among multiple cell types to control and coordinate lineage specification, cell proliferation, differentiation, migration, morphogenesis, and injury repair. A better understanding of the processes that regulate lung development, particularly alveologenesis, will have a significant impact on survival rates for premature infants born with incomplete lung development and will facilitate lung injury repair and regeneration in adults. A consortium of four research centers, a data coordinating center, and a human tissue repository provides high-quality molecular data of developing human and mouse lungs. LungMAP includes mouse and human data for cross correlation of developmental processes across species. LungMAP is generating foundational data and analysis, creating a web portal for presentation of results and public sharing of data sets, establishing a repository of young human lung tissues obtained through organ donor organizations, and developing a comprehensive lung ontology that incorporates the latest findings of the consortium. The LungMAP website (www.lungmap.net) currently contains more than 6,000 high-resolution lung images and transcriptomic, proteomic, and lipidomic human and mouse data and provides scientific information to stimulate interest in research careers for young audiences. This paper presents a brief description of research conducted by the consortium, database, and portal development and upcoming features that will enhance the LungMAP experience for a community of users. PMID:28798251

LungMAP: The Molecular Atlas of Lung Development Program.

PubMed

Ardini-Poleske, Maryanne E; Clark, Robert F; Ansong, Charles; Carson, James P; Corley, Richard A; Deutsch, Gail H; Hagood, James S; Kaminski, Naftali; Mariani, Thomas J; Potter, Steven S; Pryhuber, Gloria S; Warburton, David; Whitsett, Jeffrey A; Palmer, Scott M; Ambalavanan, Namasivayam

2017-11-01

The National Heart, Lung, and Blood Institute is funding an effort to create a molecular atlas of the developing lung (LungMAP) to serve as a research resource and public education tool. The lung is a complex organ with lengthy development time driven by interactive gene networks and dynamic cross talk among multiple cell types to control and coordinate lineage specification, cell proliferation, differentiation, migration, morphogenesis, and injury repair. A better understanding of the processes that regulate lung development, particularly alveologenesis, will have a significant impact on survival rates for premature infants born with incomplete lung development and will facilitate lung injury repair and regeneration in adults. A consortium of four research centers, a data coordinating center, and a human tissue repository provides high-quality molecular data of developing human and mouse lungs. LungMAP includes mouse and human data for cross correlation of developmental processes across species. LungMAP is generating foundational data and analysis, creating a web portal for presentation of results and public sharing of data sets, establishing a repository of young human lung tissues obtained through organ donor organizations, and developing a comprehensive lung ontology that incorporates the latest findings of the consortium. The LungMAP website (www.lungmap.net) currently contains more than 6,000 high-resolution lung images and transcriptomic, proteomic, and lipidomic human and mouse data and provides scientific information to stimulate interest in research careers for young audiences. This paper presents a brief description of research conducted by the consortium, database, and portal development and upcoming features that will enhance the LungMAP experience for a community of users. Copyright © 2017 the American Physiological Society.

Lung Diseases

MedlinePlus

... 000 times. People with lung disease have difficulty breathing. Millions of people in the U.S. have lung ... pneumonia and tuberculosis, lung cancer, and many other breathing problems. Some lung diseases can lead to respiratory ...

Lung volumes and emphysema in smokers with interstitial lung abnormalities.

PubMed

Washko, George R; Hunninghake, Gary M; Fernandez, Isis E; Nishino, Mizuki; Okajima, Yuka; Yamashiro, Tsuneo; Ross, James C; Estépar, Raúl San José; Lynch, David A; Brehm, John M; Andriole, Katherine P; Diaz, Alejandro A; Khorasani, Ramin; D'Aco, Katherine; Sciurba, Frank C; Silverman, Edwin K; Hatabu, Hiroto; Rosas, Ivan O

2011-03-10

Cigarette smoking is associated with emphysema and radiographic interstitial lung abnormalities. The degree to which interstitial lung abnormalities are associated with reduced total lung capacity and the extent of emphysema is not known. We looked for interstitial lung abnormalities in 2416 (96%) of 2508 high-resolution computed tomographic (HRCT) scans of the lung obtained from a cohort of smokers. We used linear and logistic regression to evaluate the associations between interstitial lung abnormalities and HRCT measurements of total lung capacity and emphysema. Interstitial lung abnormalities were present in 194 (8%) of the 2416 HRCT scans evaluated. In statistical models adjusting for relevant covariates, interstitial lung abnormalities were associated with reduced total lung capacity (-0.444 liters; 95% confidence interval [CI], -0.596 to -0.292; P<0.001) and a lower percentage of emphysema defined by lung-attenuation thresholds of -950 Hounsfield units (-3%; 95% CI, -4 to -2; P<0.001) and -910 Hounsfield units (-10%; 95% CI, -12 to -8; P<0.001). As compared with participants without interstitial lung abnormalities, those with abnormalities were more likely to have a restrictive lung deficit (total lung capacity <80% of the predicted value; odds ratio, 2.3; 95% CI, 1.4 to 3.7; P<0.001) and were less likely to meet the diagnostic criteria for chronic obstructive pulmonary disease (COPD) (odds ratio, 0.53; 95% CI, 0.37 to 0.76; P<0.001). The effect of interstitial lung abnormalities on total lung capacity and emphysema was dependent on COPD status (P<0.02 for the interactions). Interstitial lung abnormalities were positively associated with both greater exposure to tobacco smoke and current smoking. In smokers, interstitial lung abnormalities--which were present on about 1 of every 12 HRCT scans--were associated with reduced total lung capacity and a lesser amount of emphysema. (Funded by the National Institutes of Health and the Parker B. Francis Foundation

Lung cancer mimicking lung abscess formation on CT images.

PubMed

Taira, Naohiro; Kawabata, Tsutomu; Gabe, Atsushi; Ichi, Takaharu; Kushi, Kazuaki; Yohena, Tomofumi; Kawasaki, Hidenori; Yamashiro, Toshimitsu; Ishikawa, Kiyoshi

2014-01-01

Male, 64 FINAL DIAGNOSIS: Lung pleomorphic carcinoma Symptoms: Cough • fever - Clinical Procedure: - Specialty: Oncology. Unusual clinical course. The diagnosis of lung cancer is often made based on computed tomography (CT) image findings if it cannot be confirmed on pathological examinations, such as bronchoscopy. However, the CT image findings of cancerous lesions are similar to those of abscesses.We herein report a case of lung cancer that resembled a lung abscess on CT. We herein describe the case of 64-year-old male who was diagnosed with lung cancer using surgery. In this case, it was quite difficult to distinguish between the lung cancer and a lung abscess on CT images, and a lung abscess was initially suspected due to symptoms, such as fever and coughing, contrast-enhanced CT image findings showing a ring-enhancing mass in the right upper lobe and the patient's laboratory test results. However, a pathological diagnosis of lung cancer was confirmed according to the results of a rapid frozen section biopsy of the lesion. This case suggests that physicians should not suspect both a lung abscesses and malignancy in cases involving masses presenting as ring-enhancing lesions on contrast-enhanced CT.

An analysis of clinical teacher behaviour in a nursing practicum in Taiwan.

PubMed

Hsu, Li-Ling

2006-05-01

The aim of this study was to identify and assess the teaching behaviours (knowledge, attitudes and skills) observed in nurse educators as they taught in the clinical setting. Many quantitative studies have defined and evaluated teaching effectiveness in the clinical area. Some of these studies established instruments to evaluate faculty effectiveness in the clinical setting; however, they tended to be so broad that they were of limited use in understanding clinical teaching behaviours in nursing education. This study explored clinical teaching behaviours in a nursing practicum. Ten nurse educators taught 10 students in the medical-surgical unit at a hospital in Taiwan for about four weeks. Each teacher was observed by the researcher and one other observer for two days during regularly scheduled clinical teaching time. Data collection and analysis were done by a qualitative approach. Content analysis is a process of identifying, coding and categorizing the themes in the data. The themes of clinical teaching that emerged from data analysis included teaching aims (task-oriented and learner-centred), teacher competence (teacher knowledge, instructional strategies, planning learning experience, teaching priorities, feedback and caring) and teaching commitment (professional identity and giving of self). These findings offer a holistic blueprint of clinical teaching for nursing faculty members, which will enhance the quality of nursing education. Complexity in nursing education has increased as it is challenged to meet the needs of diverse populations in rapidly evolving and highly technical health-care settings. Clinical teachers must be enabled and empowered to provide students with appropriate knowledge and skills to meet the needs of patients. To develop students' professional nursing identity now and in the future, nurse educators have to commit themselves to both nursing and teaching in clinical settings. More nurses need to be prepared for careers in education at

Lung disease - resources

MedlinePlus

Resources - lung disease ... The following organizations are good resources for information on lung disease : American Lung Association -- www.lung.org National Heart, Lung, and Blood Institute -- www.nhlbi.nih.gov ...

Lung surgery - discharge

MedlinePlus

... Read More Bronchiectasis Chronic obstructive pulmonary disease Lung cancer Lung cancer - non-small cell Lung cancer - small cell ... team. Related MedlinePlus Health Topics COPD Emphysema Lung Cancer Lung Diseases Pleural Disorders Browse the Encyclopedia A.D. ...

Noninvasive assessment of peroxidative lung damage by HIPDM lung scanning

DOE Office of Scientific and Technical Information (OSTI.GOV)

Miniati, M.; Borrelli, E.; Monti, S.

1991-03-15

The basic compound iodobenzyl-propanediamine (HIPDM), when given intravenously, is extracted by the lungs whence it is effluxed at a slow exponential rate. In humans (normal non smokers), the mean residence time ({bar t}) of 123I-HIPDM, assessed by external detection, averages 7.2 {plus minus} 1.1 hrs. Persistence of HIPDM in lungs is significantly increased in asymptomatic smokers and, to a greater extent, in patients with ARDS. Since production of free oxygen radicals reportedly occurs as a consequence of smoke exposure and in the course of acute lung injury, the authors hypothesized that the prolonged persistence of HIPDM in the lungs ofmore » smokers and of patients with ARDS might reflect a peroxidative damage of lung tissue. They tested this hypothesis in rabbits since their baseline HIPDM lung clearance is similar to that of nonsmoking humans. In rabbits, acute lung injury was induced by phorbol myristate acetate. Three hrs after PMA administration, the animals received an i.v. bolus of {sup 131}I-HIPDM. Radioactivity over the chest was recorded for 2 hrs by gamma camera and HIPDM mean residence time in the lungs was computed. Thereafter, the animals were sacrificed and their lungs were removed to measure wet/dry weight ratio as index of lung edema and malondialdehyde (MDA) content as index of lipid peroxidation. HIPDM mean residence time was positively correlated with MDA level in lung tissue, but not with wet/dry weight ratio. Noninvasive assessment of HIPDM lung kinetics may then serve as specific in vivo marker of peroxidative lung injury.« less

Lung surgery

MedlinePlus

... Lung tissue removal; Pneumonectomy; Lobectomy; Lung biopsy; Thoracoscopy; Video-assisted thoracoscopic surgery; VATS ... do surgery on your lungs are thoracotomy and video-assisted thoracoscopic surgery (VATS). Robotic surgery may also ...

Lung Emergencies

MedlinePlus

... The Marfan Foundation Marfan & Related Disorders What is Marfan Syndrome? What are Related Disorders? What are the Signs? ... Emergencies Lung Emergencies Surgeries Lung Emergencies People with Marfan syndrome can be at increased risk of sudden lung ...

Lung Cancer—Patient Version

Cancer.gov

The two main types of lung cancer are non-small cell lung cancer and small cell lung cancer. Smoking causes most lung cancers, but nonsmokers can also develop lung cancer. Start here to find information on lung cancer treatment, causes and prevention, screening, research, and statistics on lung cancer.

Lung flooding enables efficient lung sonography and tumour imaging in human ex vivo and porcine in vivo lung cancer model

PubMed Central

2013-01-01

Background Sonography has become the imaging technique of choice for guiding intraoperative interventions in abdominal surgery. Due to artefacts from residual air content, however, videothoracoscopic and open intraoperative ultrasound-guided thermoablation of lung malignancies are impossible. Lung flooding is a new method that allows complete ultrasound imaging of lungs and their tumours. Methods Fourteen resected tumourous human lung lobes were examined transpleurally with B-mode ultrasound before (in atelectasis) and after lung flooding with isotonic saline solution. In two swine, the left lung was filled with 15 ml/kg isotonic saline solution through the left side of a double-lumen tube. Lung tumours were simulated by transthoracic ultrasound-guided injection of 5 ml of purified bovine serum albumin in glutaraldehyde, centrally into the left lower lung lobe. The rate of tumour detection, the severity of disability caused by residual gas, and sonomorphology of the lungs and tumours were assessed. Results The ex vivo tumour detection rate was 100% in flooded human lung lobes and 43% (6/14) in atelectatic lungs. In all cases of atelectasis, sonographic tumour imaging was impaired by residual gas. Tumours and atelectatic tissue were isoechoic. In 28% of flooded lungs, a little residual gas was observed that did not impair sonographic tumour imaging. In contrast to tumours, flooded lung tissue was hyperechoic, homogeneous, and of fine-grained structure. Because of the bronchial wall three-laminar structure, sonographic differentiation of vessels and bronchi was possible. In all cases, malignant tumours in the flooded lung appeared well-demarcated from the lung parenchyma. Adenocarcinoma, squamous, and large cell carcinomas were hypoechoic. Bronchioloalveolar cell carcinoma was slightly hyperechoic. Transpleural sonography identifies endobronchial tumour growth and bronchial wall destruction. With transthoracic sonography, the flooded animal lung can be completely

Observations of Urban Heat Island Mitigation in California Coastal Cities due to a Sea Breeze Induced Coastal-Cooling ``REVERSE-REACTION'' to Global Warming

NASA Astrophysics Data System (ADS)

Bornstein, R. D.; Lebassi, B.; Gonzalez, J.

2010-12-01

The study evaluated long-term (1948-2005) air temperatures at over 300 urban and rural sites in California (CA) during summer (June-August, JJA). The aggregate CA results showed asymmetric warming, as daily min temperatures increased faster than daily max temperatures. The spatial distributions of daily max temperatures in the heavily urbanized South Coast and San Francisco Bay Area air basins, however, exhibited a complex pattern, with cooling at low-elevation (mainly urban) coastal-areas and warming at (mainly rural) inland areas. Previous studies have suggested that cooling summer max temperatures in CA were due to increased irrigation, coastal upwelling, or cloud cover. The current hypothesis, however, is that this temperature pattern arises from a “reverse-reaction” to greenhouse gas (GHG) induced global-warming. In this hypothesis, the global warming of inland areas resulted in an increased (cooling) sea breeze activity in coastal areas. That daytime summer coastal cooling was seen in coastal urban areas implies that urban heat island (UHI) warming was weaker than the reverse-reaction sea breeze cooling; if there was no UHI effect, then the cooling would have been even stronger. Analysis of daytime summer max temperatures at four adjacent pairs of urban and rural sites near the inland cooling-warming boundary, however, showed that the rural sites experienced cooling, while the urban sites showed warming due to UHI development. The rate of heat island growth was estimated as the sum of each urban warming rate and the absolute magnitude of the concurrent adjacent rural cooling rate. Values ranged from 0.12 to 0.55 K decade-1, and were proportional to changes in urban population and urban extent. As Sacramento, Modesto, Stockton, and San José have grown in aerial extent (21 to 59%) and population (40 to 118%), part of the observed increased JJA max values could be due to increased daytime UHI-intensity. Without UHI effects, the currently observed JJA SFBA

Lung Cancer Screening

MedlinePlus

... healthy people with a high risk of lung cancer. Lung cancer screening is recommended for older adults who ... last 15 years. What you can expect During lung cancer screening During an LDCT scan of the lungs, ...

Rheumatoid lung disease

MedlinePlus

Lung disease - rheumatoid arthritis; Rheumatoid nodules; Rheumatoid lung ... Lung problems are common in rheumatoid arthritis. They often cause no symptoms. The cause of lung disease associated with rheumatoid arthritis is unknown. Sometimes, the medicines used to ...

What Is Lung Cancer?

MedlinePlus

... Shareable Graphics Infographics “African-American Men and Lung Cancer” “Lung Cancer Is the Biggest Cancer Killer in Both ... starts in the lungs, it is called lung cancer. Lung cancer begins in the lungs and may spread ...

Interstitial Lung Diseases

MedlinePlus

Interstitial lung disease is the name for a large group of diseases that inflame or scar the lungs. The inflammation and ... is responsible for some types of interstitial lung diseases. Specific types include Black lung disease among coal ...

Survival Benefit of Lung Transplantation in the Modern Era of Lung Allocation.

PubMed

Vock, David M; Durheim, Michael T; Tsuang, Wayne M; Finlen Copeland, C Ashley; Tsiatis, Anastasios A; Davidian, Marie; Neely, Megan L; Lederer, David J; Palmer, Scott M

2017-02-01

Lung transplantation is an accepted and increasingly employed treatment for advanced lung diseases, but the anticipated survival benefit of lung transplantation is poorly understood. To determine whether and for which patients lung transplantation confers a survival benefit in the modern era of U.S. lung allocation. Data on 13,040 adults listed for lung transplantation between May 2005 and September 2011 were obtained from the United Network for Organ Sharing. A structural nested accelerated failure time model was used to model the survival benefit of lung transplantation over time. The effects of patient, donor, and transplant center characteristics on the relative survival benefit of transplantation were examined. Overall, 73.8% of transplant recipients were predicted to achieve a 2-year survival benefit with lung transplantation. The survival benefit of transplantation varied by native disease group (P = 0.062), with 2-year expected benefit in 39.2 and 98.9% of transplants occurring in those with obstructive lung disease and cystic fibrosis, respectively, and by lung allocation score at the time of transplantation (P < 0.001), with net 2-year benefit in only 6.8% of transplants occurring for lung allocation score less than 32.5 and in 99.9% of transplants for lung allocation score exceeding 40. A majority of adults undergoing transplantation experience a survival benefit, with the greatest potential benefit in those with higher lung allocation scores or restrictive native lung disease or cystic fibrosis. These results provide novel information to assess the expected benefit of lung transplantation at an individual level and to enhance lung allocation policy.

Open lung biopsy

MedlinePlus

Biopsy - open lung ... An open lung biopsy is done in the hospital using general anesthesia . This means you will be asleep and ... The open lung biopsy is done to evaluate lung problems seen on x-ray or CT scan .

Lung transplantation

PubMed Central

Afonso, José Eduardo; Werebe, Eduardo de Campos; Carraro, Rafael Medeiros; Teixeira, Ricardo Henrique de Oliveira Braga; Fernandes, Lucas Matos; Abdalla, Luis Gustavo; Samano, Marcos Naoyuki; Pêgo-Fernandes, Paulo Manuel

2015-01-01

ABSTRACT Lung transplantation is a globally accepted treatment for some advanced lung diseases, giving the recipients longer survival and better quality of life. Since the first transplant successfully performed in 1983, more than 40 thousand transplants have been performed worldwide. Of these, about seven hundred were in Brazil. However, survival of the transplant is less than desired, with a high mortality rate related to primary graft dysfunction, infection, and chronic graft dysfunction, particularly in the form of bronchiolitis obliterans syndrome. New technologies have been developed to improve the various stages of lung transplant. To increase the supply of lungs, ex vivo lung reconditioning has been used in some countries, including Brazil. For advanced life support in the perioperative period, extracorporeal membrane oxygenation and hemodynamic support equipment have been used as a bridge to transplant in critically ill patients on the waiting list, and to keep patients alive until resolution of the primary dysfunction after graft transplant. There are patients requiring lung transplant in Brazil who do not even come to the point of being referred to a transplant center because there are only seven such centers active in the country. It is urgent to create new centers capable of performing lung transplantation to provide patients with some advanced forms of lung disease a chance to live longer and with better quality of life. PMID:26154550

Registry of the Japanese Society of Lung and Heart-Lung Transplantation: the official Japanese lung transplantation report 2008.

PubMed

Shiraishi, Takeshi; Okada, Yoshinori; Sekine, Yasuo; Chida, Masayuki; Bando, Toru; Minami, Masato; Oto, Takahiro; Nagayasu, Takeshi; Date, Hiroshi; Kondo, Takashi

2009-08-01

The year 2008 marked the 10th anniversary of the Japanese lung transplantation program started in accordance with the Japanese Organ Transplant Law, which took effect in 1997. A total of 105 lung transplantations, including 39 deceased-donor transplants and 66 living-related transplants, had been performed as of the end of 2007. This article is the 2008 official report of the Japanese Society of Lung and Heart-Lung Transplantation. It summarizes the data for clinical lung transplantation during the period 1998-2007 and discusses the current status of Japanese lung transplantation. The overall 5-year survival rate was 67.0%: including 53.4% and 74.6% for deceased-donor lung transplantation and living-donor lobar lung transplantation groups, respectively. The total operation-related and 1-month mortality rates after surgery were 3.8% and 10.4%, respectively. These data are better, or at least acceptable, in comparison with the international registry data.

Pediatric Lung Transplantation.

PubMed

Sweet, Stuart C

2017-06-01

Pediatric lung transplant is a viable option for treatment of end-stage lung disease in children, with > 100 pediatric lung transplants reported to the Registry of the International Society of Heart and Lung Transplantation each year. Long-term success is limited by availability of donor organs, debilitation as a result of chronic disease, impaired mucus clearance resulting from both surgical and pharmacologic interventions, increased risk for infection resulting from immunosuppression, and most importantly late complications, such as chronic lung allograft dysfunction. Opportunities for investigation and innovation remain in all of these domains: (1) Ex vivo lung perfusion is a promising technology with the potential for increasing the lung donor pool, (2) evolving extracorporeal support strategies coupled with effective rehabilitation will effectively bridge critically ill patients to transplant, and most importantly, (3) research efforts intended to increase our understanding of the underlying mechanisms of chronic lung allograft dysfunction will ultimately lead to the development of effective therapies to prevent or treat the variety of chronic lung allograft dysfunction presentations. Copyright © 2017 by Daedalus Enterprises.

Survival Benefit of Lung Transplantation in the Modern Era of Lung Allocation

PubMed Central

Tsuang, Wayne M.; Copeland, C. Ashley Finlen; Tsiatis, Anastasios A.; Davidian, Marie; Neely, Megan L.; Lederer, David J.; Palmer, Scott M.

2017-01-01

Rationale: Lung transplantation is an accepted and increasingly employed treatment for advanced lung diseases, but the anticipated survival benefit of lung transplantation is poorly understood. Objectives: To determine whether and for which patients lung transplantation confers a survival benefit in the modern era of U.S. lung allocation. Methods: Data on 13,040 adults listed for lung transplantation between May 2005 and September 2011 were obtained from the United Network for Organ Sharing. A structural nested accelerated failure time model was used to model the survival benefit of lung transplantation over time. The effects of patient, donor, and transplant center characteristics on the relative survival benefit of transplantation were examined. Measurements and Main Results: Overall, 73.8% of transplant recipients were predicted to achieve a 2-year survival benefit with lung transplantation. The survival benefit of transplantation varied by native disease group (P = 0.062), with 2-year expected benefit in 39.2 and 98.9% of transplants occurring in those with obstructive lung disease and cystic fibrosis, respectively, and by lung allocation score at the time of transplantation (P < 0.001), with net 2-year benefit in only 6.8% of transplants occurring for lung allocation score less than 32.5 and in 99.9% of transplants for lung allocation score exceeding 40. Conclusions: A majority of adults undergoing transplantation experience a survival benefit, with the greatest potential benefit in those with higher lung allocation scores or restrictive native lung disease or cystic fibrosis. These results provide novel information to assess the expected benefit of lung transplantation at an individual level and to enhance lung allocation policy. PMID:27779905

The Murine Lung Microbiome Changes During Lung Inflammation and Intranasal Vancomycin Treatment

PubMed Central

Barfod, Kenneth Klingenberg; Vrankx, Katleen; Mirsepasi-Lauridsen, Hengameh Chloé; Hansen, Jitka Stilund; Hougaard, Karin Sørig; Larsen, Søren Thor; Ouwenhand, Arthur C.; Krogfelt, Karen Angeliki

2015-01-01

Most microbiome research related to airway diseases has focused on the gut microbiome. This is despite advances in culture independent microbial identification techniques revealing that even healthy lungs possess a unique dynamic microbiome. This conceptual change raises the question; if lung diseases could be causally linked to local dysbiosis of the local lung microbiota. Here, we manipulate the murine lung and gut microbiome, in order to show that the lung microbiota can be changed experimentally. We have used four different approaches: lung inflammation by exposure to carbon nano-tube particles, oral probiotics and oral or intranasal exposure to the antibiotic vancomycin. Bacterial DNA was extracted from broncho-alveolar and nasal lavage fluids, caecum samples and compared by DGGE. Our results show that: the lung microbiota is sex dependent and not just a reflection of the gut microbiota, and that induced inflammation can change lung microbiota. This change is not transferred to offspring. Oral probiotics in adult mice do not change lung microbiome detectible by DGGE. Nasal vancomycin can change the lung microbiome preferentially, while oral exposure does not. These observations should be considered in future studies of the causal relationship between lung microbiota and lung diseases. PMID:26668669

Double lung transplants have significantly improved survival compared with single lung transplants in high lung allocation score patients.

PubMed

Black, Matthew C; Trivedi, Jaimin; Schumer, Erin M; Bousamra, Michael; van Berkel, Victor

2014-11-01

Historically, double lung transplantation survival rates are higher than those of single lung transplantation, but in critically ill patients a single lung transplant, with less associated operative morbidity, could afford a better outcome. This article evaluates how survival is affected in patients who have a high lung allocation score (LAS) and receive a single versus a double lung transplant. The UNOS Thoracic Transplant Database for lung transplants from January 2005 to June 2012 was used for analysis. Propensity matching was used to minimize differences between the high and low LAS groups and between single and double lung transplants in the high LAS group. Within this database, there were 8,778 patients, of whom 8,050 had an LAS less than 75 and 728 had an LAS greater than or equal to 75. Kaplan-Meier survival curves stratified by high and low LAS, and by single versus double lung transplants, showed a marked decrease in survival (p<0.001) in those with a high LAS who received a single lung transplant when compared with those with a high LAS who received a double lung transplant. This was a much greater difference in survival than was present in the low LAS patient population. Despite a higher operative morbidity, patients who had a high LAS did substantially better in terms of survival if two lungs were transplanted rather than only one, with a larger difference in survival than for patients with a lower LAS. Copyright © 2014 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

Registry of the Japanese society of lung and heart-lung transplantation: the official Japanese lung transplantation report 2012.

PubMed

Oto, Takahiro; Okada, Yoshinori; Bando, Toru; Minami, Masato; Shiraishi, Takeshi; Nagayasu, Takeshi; Chida, Masayuki; Okumura, Meinoshin; Date, Hiroshi; Miyoshi, Shinichiro; Kondo, Takashi

2013-04-01

The Japanese Organ Transplant Law was amended, and the revised law took effect in July 2010 to overcome extreme donor shortage and to increase the availability of donor organs from brain-dead donors. It is now possible to procure organs from children. The year 2011 was the first year that it was possible to examine the results of this first extensive revision of the Japanese Organ Transplant Law, which took effect in 1997. Currently, seven transplant centers, including Tohoku, Dokkyo, Kyoto, Osaka, Okayama, Fukuoka and Nagasaki Universities, are authorized to perform lung transplantation in Japan, and by the end of 2011, a total of 239 lung transplants had been performed. The number of transplants per year and the ratio of brain-dead donor transplants increased dramatically after the revision of the Japanese Organ Transplant Law. The survival rates for lung transplant recipients registered with the Japanese Society for Lung and Heart-lung Transplantation were 93.3 % at 1 month, 91.5 % at 3 months, 86.3 % at 1 year, 79.0 % at 3 years, and 73.1 % at 5 years. The survival curves for brain-dead donor and living-donor lung transplantation were similar. The survival outcomes for both brain-dead and living-donor lung transplants were better than those reported by the International Society for Heart and Lung Transplantation. However, donor shortage remains a limitation of lung transplantation in Japan. The lung transplant centers in Japan should continue to make a special effort to save critically ill patients waiting for lung transplantation.

Neonatal lungs--can absolute lung resistivity be determined non-invasively?

PubMed

Brown, B H; Primhak, R A; Smallwood, R H; Milnes, P; Narracott, A J; Jackson, M J

2002-07-01

The electrical resistivity of lung tissue can be related to the structure and composition of the tissue and also to the air content. Conditions such as pulmonary oedema and emphysema have been shown to change lung resistivity. However, direct access to the lungs to enable resistivity to be measured is very difficult. We have developed a new method of using electrical impedance tomographic (EIT) measurements on a group of 142 normal neonates to determine the absolute resistivity of lung tissue. The methodology involves comparing the measured EIT data with that from a finite difference model of the thorax in which lung tissue resistivity can be changed. A mean value of 5.7 +/- 1.7 omega(m) was found over the frequency range 4 kHz to 813 kHz. This value is lower than that usually given for adult lung tissue but consistent with the literature on the composition of the neonatal lung and with structural modelling.

Ex vivo lung perfusion.

PubMed

Reeb, Jeremie; Cypel, Marcelo

2016-03-01

Lung transplantation is an established life-saving therapy for patients with end-stage lung disease. Unfortunately, greater success in lung transplantation is hindered by a shortage of lung donors and the relatively poor early-, mid-, and long-term outcomes associated with severe primary graft dysfunction. Ex vivo lung perfusion has emerged as a modern preservation technique that allows for a more accurate lung assessment and improvement in lung quality. This review outlines the: (i) rationale behind the method; (ii) techniques and protocols; (iii) Toronto ex vivo lung perfusion method; (iv) devices available; and (v) clinical experience worldwide. We also highlight the potential of ex vivo lung perfusion in leading a new era of lung preservation. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Surface current dynamics under sea breeze conditions observed by simultaneous HF radar, ADCP and drifter measurements

NASA Astrophysics Data System (ADS)

Sentchev, Alexei; Forget, Philippe; Fraunié, Philippe

2017-04-01

Ocean surface boundary layer dynamics off the southern coast of France in the NW Mediterranean is investigated by using velocity observations by high-frequency (HF) radars, surface drifting buoys and a downward-looking drifting acoustic Doppler current profiler (ADCP). The analysis confirms that velocities measured by HF radars correspond to those observed by an ADCP at the effective depth z f = k -1, where k is wavenumber of the radio wave emitted by the radar. The radials provided by the radars were in a very good agreement with in situ measurements, with the relative errors of 1 and 9 % and root mean square (RMS) differences of 0.02 and 0.04 m/s for monostatic and bistatic radar, respectively. The total radar-based velocities appeared to be slightly underestimated in magnitude and somewhat biased in direction. At the end of the survey period, the difference in the surface current direction, based on HF radar and ADCP data, attained 10°. It was demonstrated that the surface boundary layer dynamics cannot be reconstructed successfully without taking into the account velocity variation with depth. A significant misalignment of ˜30° caused by the sea breeze was documented between the HF radar (HFR-derived) surface current and the background current. It was also found that the ocean response to a moderate wind forcing was confined to the 4-m-thick upper layer. The respective Ekman current attained the maximum value of 0.15 m/s, and the current rotation was found to be lagging the wind by approximately 40 min, with the current vector direction being 15-20° to the left of the wind. The range of velocity variability due to wind forcing was found comparable with the magnitude of the background current variability.

Immersing lungs in hydrogen-rich saline attenuates lung ischaemia-reperfusion injury.

PubMed

Takahashi, Mamoru; Chen-Yoshikawa, Toyofumi F; Saito, Masao; Tanaka, Satona; Miyamoto, Ei; Ohata, Keiji; Kondo, Takeshi; Motoyama, Hideki; Hijiya, Kyoko; Aoyama, Akihiro; Date, Hiroshi

2017-03-01

Anti-oxidant effects of hydrogen have been reported in studies examining ischaemia-reperfusion injury (IRI). In this study, we evaluated the therapeutic efficacy of immersing lungs in hydrogen-rich saline on lung IRI. Lewis rats were divided into three groups: (i) sham, (ii) normal saline and (iii) hydrogen-rich saline. In the first experiment, the left thoracic cavity was filled with either normal saline or hydrogen-rich saline for 1 h. Then, we measured the hydrogen concentration in the left lung using a sensor gas chromatograph ( N = 3 per group). In the second experiment, lung IRI was induced by occlusion of the left pulmonary hilum for 1 h, followed by reperfusion for 3 h. During the ischaemic period, the left thoracic cavity was filled with either normal saline or hydrogen-rich saline. After reperfusion, we assessed lung function, histological changes and cytokine production ( N = 5-7 per group). Immersing lungs in hydrogen-rich saline resulted in an elevated hydrogen concentration in the lung (6.9 ± 2.9 μmol/1 g lung). After IRI, pulmonary function (pulmonary compliance and oxygenation levels) was significantly higher in the hydrogen-rich saline group than in the normal saline group ( P  < 0.05). Similarly, pro-inflammatory cytokine levels (interleukin-1β and interleukin-6) in the left lung were significantly lower in the hydrogen-rich saline group than in the normal saline group ( P  < 0.05). Immersing lungs in hydrogen-rich saline delivered hydrogen into the lung and consequently attenuated lung IRI. Hydrogen-rich solution appears to be a promising approach to managing lung IRI. © The Author 2016. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.

Lung lavage with oxygenated perfluorochemical liquid in acute lung injury.

PubMed

Richman, P S; Wolfson, M R; Shaffer, T H

1993-05-01

To investigate the effects of lung lavage with oxygenated liquid perfluorochemical on gas exchange, lung mechanics, and cardiac function in animals with acute lung injury. Prospective, randomized, controlled trial. Animal laboratory. Eight adult cats (2 to 4 kg, random sex). Two insults were combined to cause lung injury: oleic acid infusion and saline whole-lung wash. Animals were assigned to either the control or treatment group which consisted of a perfluorochemical liquid (Rimar 101) lavage. Perfluorochemical liquid lavage was performed three times at hourly intervals after lung injury. Three other cats with identical injury but no perfluorochemical liquid lavage served as control animals. All cats were ventilated with an FIO2 of 0.95 and positive end-expiratory pressure of 2 cm H2O continuously. Arterial blood gas tensions and pH, dynamic pulmonary compliance were measured at 15-min intervals. Cardiac index was assessed hourly, and lung fluid was collected after each of the three perfluorochemical liquid lavages. Arterial oxygen tension and pulmonary compliance deteriorated abruptly after lung injury in all cats, and improved significantly (p < .001, two-way analysis of variance) 15 mins after perfluorochemical liquid lavage. These parameters gradually returned to their baseline over 60 mins. Arterial blood pressure and cardiac index decreased after injury in all cats, and were not significantly changed after perfluorochemical liquid lavage. Hemorrhagic fluid was recovered from distal airways by perfluorochemical liquid lavage, despite prior suctioning of the airway. Perfluorochemical liquid lavage removes pulmonary edema fluid and improves gas exchange and the mechanical properties of the lung, after acute severe lung injury.

[Lung transplantation].

PubMed

Santillán-Doherty, Patricio; Jasso-Victoria, Rogelio; Olmos-Zúñiga, Raúl; Sotres-Vega, Avelina; Argote-Greene, Luis Marcelo; Escalante-Tattersfield, Tomás; Villalba-Caloca, Jaime

2005-01-01

Lung transplantation (LT) has evolved to become an important alternative in the management of patients with end-stage pulmonary disease and chronic respiratory failure. The beginnings of this technique can be traced back to the experiments of Carrel and Guthrie over a hundred years ago. However, it was not until 1963 when the first clinical experience was performed by Hardy. Clinical success did not arrive until the 1980's thanks to the works of the Toronto Lung Transplant Group. Well established criteria have been described in order to consider a patient as a potential candidate to receive a lung. Several diseases are capable of causing terminal lung damage and in general they can be classified according to their origin as obstructive (COPD, emphysema), restrictive (fibrosis), chronic infectious (cystic fibrosis, bronquiectasis), and vascular (primary pulmonary hypertension). The most frequent diagnosis is COPD. Clinically relevant modes of LT include the implant of one lung (single LT), or both lungs (bilateral sequential LT). Transplantation of the cardiopulmonary block is reserved for special situations and lobar transplantation is still considered experimental. Donor condition is essential to the success of LT. The potential donor patient frequently suffers deterioration in lung function due to edema formation or infection and both complications restrict lung's using for transplantation. Lung preservation is also limited to a short period of time which rarely exceeds 6 hours in spite of specially-designed preservative solutions such as the low potassium dextran. Outcome after LT shows current one-year survival between 65-70% with reduction to 40-45% after five years. Mortality within the first year is usually related to primary graft failure and infection. Long-term survival depends on controlling infectious problems due to immunosuppression as well as the development of bronchilitis obliterans as a manifestation of chronic rejection. LT is a therapeutic

The Helium Warm Breeze in IBEX Observations As a Result of Charge-exchange Collisions in the Outer Heliosheath

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bzowski, Maciej; Kubiak, Marzena A.; Czechowski, Andrzej

2017-08-10

We simulated the signal due to neutral He atoms, observed by the Interstellar Boundary Explorer ( IBEX ), assuming that charge-exchange collisions between neutral He atoms and He{sup +} ions operate everywhere between the heliopause and a distant source region in the local interstellar cloud, where the neutral and charged components are in thermal equilibrium. We simulated several test cases of the plasma flow within the outer heliosheath (OHS) and investigated the signal generation for plasma flows both in the absence and in the presence of the interstellar magnetic field (ISMF). We found that a signal in the portion ofmore » IBEX data identified as being due to the Warm Breeze (WB) does not arise when a homogeneous plasma flow in front of the heliopause is assumed, but it appears immediately when any reasonable disturbance in its flow due to the presence of the heliosphere is assumed. We obtained a good qualitative agreement between the data selected for comparison and the simulations for a model flow with the velocity vector of the unperturbed gas and the direction and intensity of magnetic field adopted from recent determinations. We conclude that direct-sampling observations of neutral He atoms at 1 au from the Sun are a sensitive tool for investigating the flow of interstellar matter in the OHS, that the WB is indeed the secondary population of interstellar helium, which was hypothesized earlier, and that the WB signal is consistent with the heliosphere distorted from axial symmetry by the ISMF.« less

Lung needle biopsy

MedlinePlus

... may be due to any of the following: Bacterial, viral, or fungal lung infection Cancerous cells ( lung cancer , mesothelioma) Pneumonia Risks Sometimes, a collapsed lung ( pneumothorax ) occurs after ...

Lung transplantation in adults and children: putting lung function into perspective.

PubMed

Thompson, Bruce Robert; Westall, Glen Philip; Paraskeva, Miranda; Snell, Gregory Ian

2014-11-01

The number of lung transplants performed globally continues to increase year after year. Despite this growing experience, long-term outcomes following lung transplantation continue to fall far short of that described in other solid-organ transplant settings. Chronic lung allograft dysfunction (CLAD) remains common and is the end result of exposure to a multitude of potentially injurious insults that include alloreactivity and infection among others. Central to any description of the clinical performance of the transplanted lung is an assessment of its physiology by pulmonary function testing. Spirometry and the evaluation of forced expiratory volume in 1 s and forced vital capacity, remain core indices that are measured as part of routine clinical follow-up. Spirometry, while reproducible in detecting lung allograft dysfunction, lacks specificity in differentiating the different complications of lung transplantation such as rejection, infection and bronchiolitis obliterans. However, interpretation of spirometry is central to defining the different 'chronic rejection' phenotypes. It is becoming apparent that the maximal lung function achieved following transplantation, as measured by spirometry, is influenced by a number of donor and recipient factors as well as the type of surgery performed (single vs double vs lobar lung transplant). In this review, we discuss the wide range of variables that need to be considered when interpreting lung function testing in lung transplant recipients. Finally, we review a number of novel measurements of pulmonary function that may in the future serve as better biomarkers to detect and diagnose the cause of the failing lung allograft. © 2014 Asian Pacific Society of Respirology.

Unilateral donor lung dysfunction does not preclude successful contralateral single lung transplantation.

PubMed

Puskas, J D; Winton, T L; Miller, J D; Scavuzzo, M; Patterson, G A

1992-05-01

Single lung transplantation remains limited by a severe shortage of suitable donor lungs. Potential lung donors are often deemed unsuitable because accepted criteria (both lungs clear on the chest roentgenogram, arterial oxygen tension greater than 300 mm Hg with an inspired oxygen fraction of 1.0, a positive end-expiratory pressure of 5 cm H2O, and no purulent secretions) do not distinguish between unilateral and bilateral pulmonary disease. Many adequate single lung grafts may be discarded as a result of contralateral aspiration or pulmonary trauma. We have recently used intraoperative unilateral ventilation and perfusion to assess single lung function in potential donors with contralateral lung disease. In the 11-month period ending October 1, 1990, we performed 18 single lung transplants. In four of these cases (22%), the donor chest roentgenogram or bronchoscopic examination demonstrated significant unilateral lung injury. Donor arterial oxygen tension, (inspired oxygen fraction 1.0; positive end-expiratory pressure 5 cm H2O) was below the accepted level in each case (246 +/- 47 mm Hg, mean +/- standard deviation). Through the sternotomy used for multiple organ harvest, the pulmonary artery to the injured lung was clamped. A double-lumen endotracheal tube or endobronchial balloon occlusion catheter was used to permit ventilation of the uninjured lung alone. A second measurement of arterial oxygen tension (inspired oxygen fraction 1.0; positive end-expiratory pressure 5 cm H2O) revealed excellent unilateral lung function in all four cases (499.5 +/- 43 mm Hg; p less than 0.0004). These single lung grafts (three right, one left) were transplanted uneventfully into four recipients (three with pulmonary fibrosis and one with primary pulmonary hypertension). Lung function early after transplantation was adequate in all patients. Two patients were extubated within 24 hours. There were two late deaths, one caused by rejection and Aspergillus infection and the other

Can Stem Cells be Used to Generate New Lungs? Ex Vivo Lung Bioengineering with Decellularized Whole Lung Scaffolds

PubMed Central

Wagner, Darcy E.; Bonvillain, Ryan W.; Jensen, Todd J.; Girard, Eric D.; Bunnell, Bruce A.; Finck, Christine M.; Hoffman, Andrew M.; Weiss, Daniel J.

2013-01-01

For patients with end-stage lung diseases, lung transplantation is the only available therapeutic option. However, the number of suitable donor lungs is insufficient and lung transplants are complicated by significant graft failure and complications of immunosuppressive regimens. An alternative to classic organ replacement is desperately needed. Engineering of bioartificial organs using either natural or synthetic scaffolds is an exciting new potential option for generation of functional pulmonary tissue for human clinical application. Natural organ scaffolds can be generated by decellularization of native tissues; these acellular scaffolds retain the native organ ultrastructure and can be seeded with autologous cells toward the goal of regenerating functional tissues. Several decellularization strategies have been employed for lung, however, there is no consensus on the optimal approach. A variety of cell types have been investigated as potential candidates for effective recellularization of acellular lung scaffolds. Candidate cells that might be best utilized are those which can be easily and reproducibly isolated, expanded in vitro, seeded onto decellularized matrices, induced to differentiate into pulmonary lineage cells, and which survive to functional maturity. Whole lung cell suspensions, endogenous progenitor cells, embryonic and adult stem cells, and induced pluripotent stem (iPS) cells have been investigated for their applicability to repopulate acellular lung matrices. Ideally, patient-derived autologous cells would be used for lung recellularization as they have the potential to reduce the need for post-transplant immunosuppression. Several studies have performed transplantation of rudimentary bioengineered lung scaffolds in animal models with limited, short-term functionality but much further study is needed. PMID:23614471

RANK rewires energy homeostasis in lung cancer cells and drives primary lung cancer

PubMed Central

Rao, Shuan; Sigl, Verena; Wimmer, Reiner Alois; Novatchkova, Maria; Jais, Alexander; Wagner, Gabriel; Handschuh, Stephan; Uribesalgo, Iris; Hagelkruys, Astrid; Kozieradzki, Ivona; Tortola, Luigi; Nitsch, Roberto; Cronin, Shane J.; Orthofer, Michael; Branstetter, Daniel; Canon, Jude; Rossi, John; D'Arcangelo, Manolo; Botling, Johan; Micke, Patrick; Fleur, Linnea La; Edlund, Karolina; Bergqvist, Michael; Ekman, Simon; Lendl, Thomas; Popper, Helmut; Takayanagi, Hiroshi; Kenner, Lukas; Hirsch, Fred R.; Dougall, William

2017-01-01

Lung cancer is the leading cause of cancer deaths. Besides smoking, epidemiological studies have linked female sex hormones to lung cancer in women; however, the underlying mechanisms remain unclear. Here we report that the receptor activator of nuclear factor-kB (RANK), the key regulator of osteoclastogenesis, is frequently expressed in primary lung tumors, an active RANK pathway correlates with decreased survival, and pharmacologic RANK inhibition reduces tumor growth in patient-derived lung cancer xenografts. Clonal genetic inactivation of KRasG12D in mouse lung epithelial cells markedly impairs the progression of KRasG12D-driven lung cancer, resulting in a significant survival advantage. Mechanistically, RANK rewires energy homeostasis in human and murine lung cancer cells and promotes expansion of lung cancer stem-like cells, which is blocked by inhibiting mitochondrial respiration. Our data also indicate survival differences in KRasG12D-driven lung cancer between male and female mice, and we show that female sex hormones can promote lung cancer progression via the RANK pathway. These data uncover a direct role for RANK in lung cancer and may explain why female sex hormones accelerate lung cancer development. Inhibition of RANK using the approved drug denosumab may be a therapeutic drug candidate for primary lung cancer. PMID:29118048

Frequency and number of ultrasound lung rockets (B-lines) using a regionally based lung ultrasound examination named vet BLUE (veterinary bedside lung ultrasound exam) in dogs with radiographically normal lung findings.

PubMed

Lisciandro, Gregory R; Fosgate, Geoffrey T; Fulton, Robert M

2014-01-01

Lung ultrasound is superior to lung auscultation and supine chest radiography for many respiratory conditions in human patients. Ultrasound diagnoses are based on easily learned patterns of sonographic findings and artifacts in standardized images. By applying the wet lung (ultrasound lung rockets or B-lines, representing interstitial edema) versus dry lung (A-lines with a glide sign) concept many respiratory conditions can be diagnosed or excluded. The ultrasound probe can be used as a visual stethoscope for the evaluation of human lungs because dry artifacts (A-lines with a glide sign) predominate over wet artifacts (ultrasound lung rockets or B-lines). However, the frequency and number of wet lung ultrasound artifacts in dogs with radiographically normal lungs is unknown. Thus, the primary objective was to determine the baseline frequency and number of ultrasound lung rockets in dogs without clinical signs of respiratory disease and with radiographically normal lung findings using an 8-view novel regionally based lung ultrasound examination called Vet BLUE. Frequency of ultrasound lung rockets were statistically compared based on signalment, body condition score, investigator, and reasons for radiography. Ten left-sided heart failure dogs were similarly enrolled. Overall frequency of ultrasound lung rockets was 11% (95% confidence interval, 6-19%) in dogs without respiratory disease versus 100% (95% confidence interval, 74-100%) in those with left-sided heart failure. The low frequency and number of ultrasound lung rockets observed in dogs without respiratory disease and with radiographically normal lungs suggests that Vet BLUE will be clinically useful for the identification of canine respiratory conditions. © 2014 American College of Veterinary Radiology.

Classification algorithm of lung lobe for lung disease cases based on multislice CT images

NASA Astrophysics Data System (ADS)

Matsuhiro, M.; Kawata, Y.; Niki, N.; Nakano, Y.; Mishima, M.; Ohmatsu, H.; Tsuchida, T.; Eguchi, K.; Kaneko, M.; Moriyama, N.

2011-03-01

With the development of multi-slice CT technology, to obtain an accurate 3D image of lung field in a short time is possible. To support that, a lot of image processing methods need to be developed. In clinical setting for diagnosis of lung cancer, it is important to study and analyse lung structure. Therefore, classification of lung lobe provides useful information for lung cancer analysis. In this report, we describe algorithm which classify lungs into lung lobes for lung disease cases from multi-slice CT images. The classification algorithm of lung lobes is efficiently carried out using information of lung blood vessel, bronchus, and interlobar fissure. Applying the classification algorithms to multi-slice CT images of 20 normal cases and 5 lung disease cases, we demonstrate the usefulness of the proposed algorithms.

[A new medical education using a lung sound auscultation simulator called "Mr. Lung"].

PubMed

Yoshii, Chiharu; Anzai, Takashi; Yatera, Kazuhiro; Kawajiri, Tatsunori; Nakashima, Yasuhide; Kido, Masamitsu

2002-09-01

We developed a lung sound auscultation simulator "Mr. Lung" in 2001. To improve the auscultation skills of lung sounds, we utilized this new device in our educational training facility. From June 2001 to March 2002, we used "Mr. Lung" for our small group training in which one hundred of the fifth year medical students were divided into small groups from which one group was taught every other week. The class consisted of ninety-minute training periods for auscultation of lung sounds. At first, we explained the classification of lung sounds, and then auscultation tests were performed. Namely, students listened to three cases of abnormal or adventitious lung sounds on "Mr. Lung" through their stethoscopes. Next they answered questions corresponding to the portion and quality of the sounds. Then, we explained the correct answers and how to differentiate lung sounds on "Mr. Lung". Additionally, at the beginning and the end of the lecture, five degrees of self-assessment for the auscultation of the lung sounds were performed. The ratio of correct answers for lung sounds were 36.9% for differences between bilateral lung sounds, 52.5% for coarse crackles, 34.1% for fine crackles, 69.2% for wheezes, 62.1% for rhonchi and 22.2% for stridor. Self-assessment scores were significantly higher after the class than before. The ratio of correct lung sound answers was surprisingly low among medical students. We believe repetitive auscultation of the simulator to be extremely helpful for medical education.

Lung diffusion testing

MedlinePlus

... page: //medlineplus.gov/ency/article/003854.htm Lung diffusion testing To use the sharing features on this page, please enable JavaScript. Lung diffusion testing measures how well the lungs exchange gases. ...

Epidemiology of Lung Cancer

PubMed Central

Brock, Malcolm V.; Ford, Jean G.; Samet, Jonathan M.; Spivack, Simon D.

2013-01-01

Background: Ever since a lung cancer epidemic emerged in the mid-1900s, the epidemiology of lung cancer has been intensively investigated to characterize its causes and patterns of occurrence. This report summarizes the key findings of this research. Methods: A detailed literature search provided the basis for a narrative review, identifying and summarizing key reports on population patterns and factors that affect lung cancer risk. Results: Established environmental risk factors for lung cancer include smoking cigarettes and other tobacco products and exposure to secondhand tobacco smoke, occupational lung carcinogens, radiation, and indoor and outdoor air pollution. Cigarette smoking is the predominant cause of lung cancer and the leading worldwide cause of cancer death. Smoking prevalence in developing nations has increased, starting new lung cancer epidemics in these nations. A positive family history and acquired lung disease are examples of host factors that are clinically useful risk indicators. Risk prediction models based on lung cancer risk factors have been developed, but further refinement is needed to provide clinically useful risk stratification. Promising biomarkers of lung cancer risk and early detection have been identified, but none are ready for broad clinical application. Conclusions: Almost all lung cancer deaths are caused by cigarette smoking, underscoring the need for ongoing efforts at tobacco control throughout the world. Further research is needed into the reasons underlying lung cancer disparities, the causes of lung cancer in never smokers, the potential role of HIV in lung carcinogenesis, and the development of biomarkers. PMID:23649439

RANK rewires energy homeostasis in lung cancer cells and drives primary lung cancer.

PubMed

Rao, Shuan; Sigl, Verena; Wimmer, Reiner Alois; Novatchkova, Maria; Jais, Alexander; Wagner, Gabriel; Handschuh, Stephan; Uribesalgo, Iris; Hagelkruys, Astrid; Kozieradzki, Ivona; Tortola, Luigi; Nitsch, Roberto; Cronin, Shane J; Orthofer, Michael; Branstetter, Daniel; Canon, Jude; Rossi, John; D'Arcangelo, Manolo; Botling, Johan; Micke, Patrick; Fleur, Linnea La; Edlund, Karolina; Bergqvist, Michael; Ekman, Simon; Lendl, Thomas; Popper, Helmut; Takayanagi, Hiroshi; Kenner, Lukas; Hirsch, Fred R; Dougall, William; Penninger, Josef M

2017-10-15

Lung cancer is the leading cause of cancer deaths. Besides smoking, epidemiological studies have linked female sex hormones to lung cancer in women; however, the underlying mechanisms remain unclear. Here we report that the receptor activator of nuclear factor-kB (RANK), the key regulator of osteoclastogenesis, is frequently expressed in primary lung tumors, an active RANK pathway correlates with decreased survival, and pharmacologic RANK inhibition reduces tumor growth in patient-derived lung cancer xenografts. Clonal genetic inactivation of KRas G12D in mouse lung epithelial cells markedly impairs the progression of KRas G12D -driven lung cancer, resulting in a significant survival advantage. Mechanistically, RANK rewires energy homeostasis in human and murine lung cancer cells and promotes expansion of lung cancer stem-like cells, which is blocked by inhibiting mitochondrial respiration. Our data also indicate survival differences in KRas G12D -driven lung cancer between male and female mice, and we show that female sex hormones can promote lung cancer progression via the RANK pathway. These data uncover a direct role for RANK in lung cancer and may explain why female sex hormones accelerate lung cancer development. Inhibition of RANK using the approved drug denosumab may be a therapeutic drug candidate for primary lung cancer. © 2017 Rao et al.; Published by Cold Spring Harbor Laboratory Press.

Amiodarone causes acute oxidant lung injury in ventilated and perfused rabbit lungs.

PubMed

Kennedy, T P; Gordon, G B; Paky, A; McShane, A; Adkinson, N F; Peters, S P; Friday, K; Jackman, W; Sciuto, A M; Gurtner, G H

1988-07-01

Amiodarone (ADR), a new antiarrhythmic drug for life-threatening cardiac arrhythmias, causes pneumonitis or lung fibrosis in a sizeable minority of patients. The cause of lung damage is not known. We have shown that infusion of 10 mg amiodarone into the inflow circuit of ventilated and perfused rabbit lungs causes immediate increase in pulmonary artery pressure (mean +/- SEM) (from 13.6 +/- 1.2 to 40.6 +/- 9.5 mm Hg, p less than 0.01) and pulmonary edema with marked increase in the pulmonary generation of thromboxane and leukotrienes C4 and/or D4. Albumin (2 g%) in the perfusate prevents any increase in lung perfusion pressure or edema formation. When lung perfusion pressure increase is blocked with the combined cyclooxygenase and lipoxygenase inhibitor enolicam sodium (CG5391B, 35 microM in perfusate), significant lung edema still occurs after amiodarone, indicating that amiodarone causes increased alveolar-capillary membrane permeability. Addition of catalase (100 U/ml) or superoxide dismutase and catalase (100 U/ml each) to perfusate fails to protect from amiodarone lung injury. Immediate infusion of amiodarone (10 mg) into lungs ventilated with room air (ADR + RA) causes an increase in lung weight gain from baseline (delta W) of 5.7 +/- 1.5 g/min. Compared with ADR + RA, ventilation of lungs with 4% O2 (delta W = 0.7 +/- 0.3 g/min, p less than 0.05), pretreatment of rabbits for 3 days with butylated hydroxyanisole (BHA, 100 mg/kg/day i.p., delta W = 0.05 +/- 0.02 g/min, p less than 0.01), pretreatment of rabbits for 3 days with vitamin E (Vit E, 300 U/day orally, delta W = 0.6 +/- 0.2 g/min, p less than 0.05), or addition of N-acetylcysteine to the lung perfusate (NAC, 5 mM, delta W = 0.1 +/- 0.08 g/min, p less than 0.01) all protect from lung edema formation after amiodarone. Amiodarone (100 mg) also caused a marked increase in luminol-enhanced lung chemiluminescence, lung production of superoxide anion (O2-), and tissue levels of lung glutathione disulfide

Photovoltaic at Hollywood and Desert Breeze Recreational Centers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ammerman, Shane

Executive Summary Renewable Energy Initiatives for Clark County Parks and Recreation Solar Project DOE grant # DE-EE0003180 In accordance with the goals of the Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy for promoting solar energy as clean, carbon-free and cost-effective, the County believed that a recreational center was an ideal place to promote solar energy technologies to the public. This project included the construction of solar electricity generation facilities (40kW) at two Clark County facility sites, Desert Breeze Recreational Center and Hollywood Recreational Center, with educational kiosks and Green Boxes for classroom instruction. The major objectivesmore » and goals of this Solar Project include demonstration of state of the art technologies for the generation of electricity from solar technology and the creation of an informative and educational tool in regards to the benefits and process of generating alternative energy. Clark County partnered with Anne Johnson (design architect/consultant), Affiliated Engineers Inc. (AEI), Desert Research Institute (DRI), and Morse Electric. The latest photovoltaic technologies were used in the project to help create the greatest expected energy savings for60443 each recreational center. This coupled with the data created from the monitoring system will help Clark County and NREL further understand the real time outputs from the system. The educational portion created with AEI and DRI incorporates material for all ages with a focus on K - 12. The AEI component is an animated story telling the fundamentals of how sunlight is turned into electricity and DRI‘s creation of Solar Green Boxes brings environmental education into the classroom. In addition to the educational component for the public, the energy that is created through the photovoltaic system also translates into saved money and health benefits for the general public. This project has helped Clark County to further add to

Meta-markers for the differential diagnosis of lung cancer and lung disease.

PubMed

Kim, Yong-In; Ahn, Jung-Mo; Sung, Hye-Jin; Na, Sang-Su; Hwang, Jaesung; Kim, Yongdai; Cho, Je-Yoel

2016-10-04

Misdiagnosis of lung cancer remains a serious problem due to the difficulty of distinguishing lung cancer from other respiratory lung diseases. As a result, the development of serum-based differential diagnostic biomarkers is in high demand. In this study, 198 clinical serum samples from non-cancer lung disease and lung cancer patients were analyzed using nLC-MRM-MS for the levels of seven lung cancer biomarker candidates. When the candidates were assessed individually, only SERPINEA4 showed statistically significant changes in the serum levels. The MRM results and clinical information were analyzed using a logistic regression analysis to select model for the best 'meta-marker', or combination of biomarkers for differential diagnosis. Also, under consideration of statistical interaction, variables having low significance as a single factor but statistically influencing on meta-marker model were selected. Using this probabilistic classification, the best meta-marker was determined to be made up of two proteins SERPINA4 and PON1 with age factor. This meta-marker showed an enhanced differential diagnostic capability (AUC=0.915) for distinguishing the two patient groups. Our results suggest that a statistical model can determine optimal meta-markers, which may have better specificity and sensitivity than a single biomarker and thus improve the differential diagnosis of lung cancer and lung disease patients. Diagnosing lung cancer commonly involves the use of radiographic methods. However, an imaging-based diagnosis may fail to differentiate lung cancer from non-cancerous lung disease. In this study, we examined several serum proteins in the sera of 198 lung cancer and non-cancerous lung disease patients by multiple-reaction monitoring. We then used a combination of variables to generate a meta-marker model that is useful as a differential diagnostic biomarker. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.

Lung tumor motion prediction during lung brachytherapy using finite element model

NASA Astrophysics Data System (ADS)

Shirzadi, Zahra; Sadeghi Naini, Ali; Samani, Abbas

2012-02-01

A biomechanical model is proposed to predict deflated lung tumor motion caused by diaphragm respiratory motion. This model can be very useful for targeting the tumor in tumor ablative procedures such as lung brachytherapy. To minimize motion within the target lung, these procedures are performed while the lung is deflated. However, significant amount of tissue deformation still occurs during respiration due to the diaphragm contact forces. In the absence of effective realtime image guidance, biomechanical models can be used to estimate tumor motion as a function of diaphragm's position. To develop this model, Finite Element Method (FEM) was employed. To demonstrate the concept, we conducted an animal study of an ex-vivo porcine deflated lung with a tumor phantom. The lung was deformed by compressing a diaphragm mimicking cylinder against it. Before compression, 3D-CT image of this lung was acquired, which was segmented and turned into FE mesh. The lung tissue was modeled as hyperelastic material with a contact loading to calculate the lung deformation and tumor motion during respiration. To validate the results from FE model, the motion of a small area on the surface close to the tumor was tracked while the lung was being loaded by the cylinder. Good agreement was demonstrated between the experiment results and simulation results. Furthermore, the impact of tissue hyperelastic parameters uncertainties in the FE model was investigated. For this purpose, we performed in-silico simulations with different hyperelastic parameters. This study demonstrated that the FEM was accurate and robust for tumor motion prediction.

Attenuation of Lipopolysaccharide-Induced Lung Vascular Stiffening by Lipoxin Reduces Lung Inflammation

PubMed Central

Meng, Fanyong; Mambetsariev, Isa; Tian, Yufeng; Beckham, Yvonne; Meliton, Angelo; Leff, Alan; Gardel, Margaret L.; Allen, Michael J.; Birukov, Konstantin G.

2015-01-01

Reversible changes in lung microstructure accompany lung inflammation, although alterations in tissue micromechanics and their impact on inflammation remain unknown. This study investigated changes in extracellular matrix (ECM) remodeling and tissue stiffness in a model of LPS-induced inflammation and examined the role of lipoxin analog 15-epi-lipoxin A4 (eLXA4) in the reduction of stiffness-dependent exacerbation of the inflammatory process. Atomic force microscopy measurements of live lung slices were used to directly measure local tissue stiffness changes induced by intratracheal injection of LPS. Effects of LPS on ECM properties and inflammatory response were evaluated in an animal model of LPS-induced lung injury, live lung tissue slices, and pulmonary endothelial cell (EC) culture. In vivo, LPS increased perivascular stiffness in lung slices monitored by atomic force microscopy and stimulated expression of ECM proteins fibronectin, collagen I, and ECM crosslinker enzyme, lysyl oxidase. Increased stiffness and ECM remodeling escalated LPS-induced VCAM1 and ICAM1 expression and IL-8 production by lung ECs. Stiffness-dependent exacerbation of inflammatory signaling was confirmed in pulmonary ECs grown on substrates with high and low stiffness. eLXA4 inhibited LPS-increased stiffness in lung cross sections, attenuated stiffness-dependent enhancement of EC inflammatory activation, and restored lung compliance in vivo. This study shows that increased local vascular stiffness exacerbates lung inflammation. Attenuation of local stiffening of lung vasculature represents a novel mechanism of lipoxin antiinflammatory action. PMID:24992633

Lung scintigraphy in differential diagnosis of peripheral lung cancer and community-acquired pneumonia

NASA Astrophysics Data System (ADS)

Krivonogov, Nikolay G.; Efimova, Nataliya Y.; Zavadovsky, Konstantin W.; Lishmanov, Yuri B.

2016-08-01

Ventilation/perfusion lung scintigraphy was performed in 39 patients with verified diagnosis of community-acquired pneumonia (CAP) and in 14 patients with peripheral lung cancer. Ventilation/perfusion ratio, apical-basal gradients of ventilation (U/L(V)) and lung perfusion (U/L(P)), and alveolar capillary permeability of radionuclide aerosol were determined based on scintigraphy data. The study demonstrated that main signs of CAP were increases in ventilation/perfusion ratio, perfusion and ventilation gradient on a side of the diseased lung, and two-side increase in alveolar capillary permeability rate for radionuclide aerosol. Unlike this, scintigraphic signs of peripheral lung cancer comprise an increase in ventilation/perfusion ratio over 1.0 on a side of the diseased lung with its simultaneous decrease on a contralateral side, normal values of perfusion and ventilation gradients of both lungs, and delayed alveolar capillary clearance in the diseased lung compared with the intact lung.

Lung cancer - small cell

MedlinePlus

Cancer - lung - small cell; Small cell lung cancer; SCLC ... About 15% of all lung cancer cases are SCLC. Small cell lung cancer is slightly more common in men than women. Almost all cases of SCLC are ...

Ex Vivo Lung Perfusion Rehabilitates Sepsis-Induced Lung Injury

PubMed Central

Mehaffey, J. Hunter; Charles, Eric J.; Sharma, Ashish K.; Salmon, Morgan; Money, Dustin; Schubert, Sarah; Stoler, Mark H; Tribble, Curtis G.; Laubach, Victor E.; Roeser, Mark E.; Kron, Irving L.

2017-01-01

Objective Sepsis is the number one cause of lung injury in adults. Ex vivo lung perfusion (EVLP) is gaining clinical acceptance for donor lung evaluation and rehabilitation, and may expand the use of marginal organs for transplantation. We hypothesized that four hours of normothermic EVLP would improve compliance and oxygenation in a porcine model of sepsis-induced lung injury. Methods We utilized a porcine lung injury model using intravenous lipopolysaccharide (LPS) to induce a systemic inflammatory response. Two groups (n=4 animals/group) received a 2-hour infusion of LPS via the external jugular vein. Serial blood gases were performed every 30 min until the PO2/FiO2 ratio dropped below 150 on two consecutive readings. Lungs were then randomized to treatment with 4 hours of normothermic EVLP with Steen solution or 4 additional hours of in vivo perfusion (Control). Airway pressures and blood gases were recorded for calculation of dynamic lung compliance and PO2/FiO2 ratios. EVLP was performed according to the NOVEL trial protocol with hourly recruitment maneuvers and oxygen challenge. Results All animals reached a PO2/FiO2 ratio < 150 mmHg within 3 hours after start of LPS infusion. Animals in the Control group had continued decline of oxygenation and compliance during the 4-hour in vivo perfusion period with three of the four animals dying within 4 hours due to severe hypoxia. The EVLP group demonstrated significant improvements in oxygenation and dynamic compliance from hour 1 to hour 4 (365.8±53.0 vs 584.4±21.0 mmHg, p=0.02; 9.0±2.8 vs 15.0±3.6, p=0.02 mL/cmH2O). Conclusions EVLP can successfully rehabilitate LPS-induced lung injury in this preclinical porcine model. Thus EVLP may provide a means to rehabilitate many types of acute lung injury. PMID:28434548

Impacts of lung and tumor volumes on lung dosimetry for nonsmall cell lung cancer.

PubMed

Lei, Weijie; Jia, Jing; Cao, Ruifen; Song, Jing; Hu, Liqin

2017-09-01

The purpose of this study was to determine the impacts of lung and tumor volumes on normal lung dosimetry in three-dimensional conformal radiotherapy (3DCRT), step-and-shoot intensity-modulated radiotherapy (ssIMRT), and single full-arc volumetric-modulated arc therapy (VMAT) in treatment of nonsmall cell lung cancers (NSCLC). All plans were designed to deliver a total dose of 66 Gy in 33 fractions to PTV for the 32 NSCLC patients with various total (bilateral) lung volumes, planning target volumes (PTVs), and PTV locations. The ratio of the lung volume (total lung volume excluding the PTV volume) to the PTV volume (LTR) was evaluated to represent the impacts in three steps. (a) The least squares method was used to fit mean lung doses (MLDs) to PTVs or LTRs with power-law function in the population cohort (N = 32). (b) The population cohort was divided into three groups by LTRs based on first step and then by PTVs, respectively. The MLDs were compared among the three techniques in each LTR group (LG) and each PTV group (PG). (c) The power-law correlation was tested by using the adaptive radiation therapy (ART) planning data of individual patients in the individual cohort (N = 4). Different curves of power-law function with high R 2 values were observed between averaged LTRs and averaged MLDs for 3DCRT, ssIMRT, and VMAT, respectively. In the individual cohort, high R 2 values of fitting curves were also observed in individual patients in ART, although the trend was highly patient-specific. There was a more obvious correlation between LTR and MLD than that between PTV and MLD. © 2017 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine.

Surgical and survival outcomes of lung cancer patients with intratumoral lung abscesses.

PubMed

Yamanashi, Keiji; Okumura, Norihito; Takahashi, Ayuko; Nakashima, Takashi; Matsuoka, Tomoaki

2017-05-26

Intratumoral lung abscess is a secondary lung abscess that is considered to be fatal. Therefore, surgical procedures, although high-risk, have sometimes been performed for intratumoral lung abscesses. However, no studies have examined the surgical outcomes of non-small cell lung cancer patients with intratumoral lung abscesses. The aim of this study was to investigate the surgical and survival outcomes of non-small cell lung cancer patients with intratumoral lung abscesses. Eleven consecutive non-small cell lung cancer patients with intratumoral lung abscesses, who had undergone pulmonary resection at our institution between January 2007 and December 2015, were retrospectively analysed. The post-operative prognoses were investigated and prognostic factors were evaluated. Ten of 11 patients were male and one patient was female. The median age was 64 (range, 52-80) years. Histopathologically, 4 patients had Stage IIA, 2 patients had Stage IIB, 2 patients had Stage IIIA, and 3 patients had Stage IV tumors. The median operative time was 346 min and the median amount of bleeding was 1327 mL. The post-operative morbidity and mortality rates were 63.6% and 0.0%, respectively. Recurrence of respiratory infections, including lung abscesses, was not observed in all patients. The median post-operative observation period was 16.1 (range, 1.3-114.5) months. The 5-year overall survival rate was 43.3%. No pre-operative, intra-operative, or post-operative prognostic factors were identified in the univariate analyses. Surgical procedures for advanced-stage non-small cell lung cancer patients with intratumoral lung abscesses, although high-risk, led to satisfactory post-operative mortality rates and acceptable prognoses.

Lung scintigraphy in differential diagnosis of peripheral lung cancer and community-acquired pneumonia

DOE Office of Scientific and Technical Information (OSTI.GOV)

Krivonogov, Nikolay G., E-mail: kng@cardio-tomsk.ru; Efimova, Nataliya Y., E-mail: efimova@cardio-tomsk.ru; Zavadovsky, Konstantin W.

Ventilation/perfusion lung scintigraphy was performed in 39 patients with verified diagnosis of community-acquired pneumonia (CAP) and in 14 patients with peripheral lung cancer. Ventilation/perfusion ratio, apical-basal gradients of ventilation (U/L(V)) and lung perfusion (U/L(P)), and alveolar capillary permeability of radionuclide aerosol were determined based on scintigraphy data. The study demonstrated that main signs of CAP were increases in ventilation/perfusion ratio, perfusion and ventilation gradient on a side of the diseased lung, and two-side increase in alveolar capillary permeability rate for radionuclide aerosol. Unlike this, scintigraphic signs of peripheral lung cancer comprise an increase in ventilation/perfusion ratio over 1.0 on amore » side of the diseased lung with its simultaneous decrease on a contralateral side, normal values of perfusion and ventilation gradients of both lungs, and delayed alveolar capillary clearance in the diseased lung compared with the intact lung.« less

Lung regeneration by fetal lung tissue implantation in a mouse pulmonary emphysema model.

PubMed

Uyama, Koh; Sakiyama, Shoji; Yoshida, Mitsuteru; Kenzaki, Koichiro; Toba, Hiroaki; Kawakami, Yukikiyo; Okumura, Kazumasa; Takizawa, Hiromitsu; Kondo, Kazuya; Tangoku, Akira

2016-01-01

The mortality and morbidity of chronic obstructive pulmonary disease are high. However, no radical therapy has been developed to date. The purpose of this study was to evaluate whether fetal mouse lung tissue can grow and differentiate in the emphysematous lung. Fetal lung tissue from green fluorescent protein C57BL/6 mice at 16 days' gestation was used as donor material. Twelve-month-old pallid mice were used as recipients. Donor lungs were cut into small pieces and implanted into the recipient left lung by performing thoracotomy under anesthesia. The recipient mice were sacrificed at day 7, 14, and 28 after implantation and used for histological examination. Well-developed spontaneous pulmonary emphysema was seen in 12-month-old pallid mice. Smooth and continuous connection between implanted fetal lung tissue and recipient lung was recognized. Air space expansion and donor tissue differentiation were observed over time. We could clearly distinguish the border zones between injected tissue and native tissue by the green fluorescence of grafts. Fetal mouse lung fragments survived and differentiated in the emphysematous lung of pallid mice. Implantation of fetal lung tissue in pallid mice might lead to further lung regeneration research from the perspective of respiratory and exercise function. J. Med. Invest. 63: 182-186, August, 2016.

Lung transplantation with lungs from older donors: recipient and surgical factors affect outcomes.

PubMed

Shigemura, Norihisa; Horai, Tetsuya; Bhama, Jay K; D'Cunha, Jonathan; Zaldonis, Diana; Toyoda, Yoshiya; Pilewski, Joseph M; Luketich, James D; Bermudez, Christian A

2014-10-27

A shortage of donors has compelled the use of extended-criteria donor organs in lung transplantation. The purpose of this study was to evaluate the impact of using older donors on outcomes after lung transplantation using current protocols. From January 2003 to August 2009, 593 lung transplants were performed at our institution. We compared 87 patients (14.7%) who received lungs from donors aged 55 years or older with 506 patients who received lungs from donors less than 55 years old. We also examined risk factors for mortality in recipients of lungs from older donors. The incidence of major complications including severe primary graft dysfunction and early mortality rates were similar between the groups. However, posttransplant peak FEV1 was lower in the patients who received lungs from older donors (71.7% vs. 80.7%, P<0.05). In multivariate analysis, recipient pulmonary hypertension (transpulmonary pressure gradient >20 mm Hg) and prolonged intraoperative cardiopulmonary bypass were significant risk factors for mortality in the recipients of lungs from older donors. This large, single-center experience demonstrated that transplanting lungs from donors older than 55 years did not yield worse short- or long-term outcomes as compared with transplanting lungs from younger donors. However, transplanting lungs from older donors into recipients with pulmonary hypertension or recipients who required prolonged cardiopulmonary bypass increased the risk for mortality. Although lungs from older donors should not be excluded because of donor age alone, surgeons should carefully consider their patient selection criteria and surgical plans when transplanting lungs from older donors.

Serial perfusion in native lungs in patients with idiopathic pulmonary fibrosis and other interstitial lung diseases after single lung transplantation.

PubMed

Sokai, Akihiko; Handa, Tomohiro; Chen, Fengshi; Tanizawa, Kiminobu; Aoyama, Akihiro; Kubo, Takeshi; Ikezoe, Kohei; Nakatsuka, Yoshinari; Oguma, Tsuyoshi; Hirai, Toyohiro; Nagai, Sonoko; Chin, Kazuo; Date, Hiroshi; Mishima, Michiaki

2016-04-01

Lung perfusions after single lung transplantation (SLT) have not been fully clarified in patients with interstitial lung disease (ILD). The present study aimed to investigate temporal changes in native lung perfusion and their associated clinical factors in patients with ILD who have undergone SLT. Eleven patients were enrolled. Perfusion scintigraphy was serially performed up to 12 months after SLT. Correlations between the post-operative perfusion ratio in the native lung and clinical parameters, including pre-operative perfusion ratio and computed tomography (CT) volumetric parameters, were evaluated. On average, the perfusion ratio of the native lung was maintained at approximately 30% until 12 months after SLT. However, the ratio declined more significantly in idiopathic pulmonary fibrosis (IPF) than in other ILDs (p = 0.014). The perfusion ratio before SLT was significantly correlated with that at three months after SLT (ρ = 0.64, p = 0.048). The temporal change of the perfusion ratio in the native lung did not correlate with those of the CT parameters. The pre-operative perfusion ratio may predict the post-operative perfusion ratio of the native lung shortly after SLT in ILD. Perfusion of the native lung may decline faster in IPF compared with other ILDs. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Lung volumes predict survival in patients with chronic lung allograft dysfunction.

PubMed

Kneidinger, Nikolaus; Milger, Katrin; Janitza, Silke; Ceelen, Felix; Leuschner, Gabriela; Dinkel, Julien; Königshoff, Melanie; Weig, Thomas; Schramm, René; Winter, Hauke; Behr, Jürgen; Neurohr, Claus

2017-04-01

Identification of disease phenotypes might improve the understanding of patients with chronic lung allograft dysfunction (CLAD). The aim of the study was to assess the impact of pulmonary restriction and air trapping by lung volume measurements at the onset of CLAD.A total of 396 bilateral lung transplant recipients were analysed. At onset, CLAD was further categorised based on plethysmography. A restrictive CLAD (R-CLAD) was defined as a loss of total lung capacity from baseline. CLAD with air trapping (AT-CLAD) was defined as an increased ratio of residual volume to total lung capacity. Outcome was survival after CLAD onset. Patients with insufficient clinical information were excluded (n=95).Of 301 lung transplant recipients, 94 (31.2%) developed CLAD. Patients with R-CLAD (n=20) and AT-CLAD (n=21), respectively, had a significantly worse survival (p<0.001) than patients with non-R/AT-CLAD. Both R-CLAD and AT-CLAD were associated with increased mortality when controlling for multiple confounding variables (hazard ratio (HR) 3.57, 95% CI 1.39-9.18; p=0.008; and HR 2.65, 95% CI 1.05-6.68; p=0.039). Furthermore, measurement of lung volumes was useful to identify patients with combined phenotypes.Measurement of lung volumes in the long-term follow-up of lung transplant recipients allows the identification of patients who are at risk for worse outcome and warrant special consideration. Copyright ©ERS 2017.

Importance of the lung perfusion scintigraphy in single lung transplantation.

PubMed

Rodríguez Mesa, N V; Guerrero Cancio, M C; Cordero Jiménez, M D; Alvarez Velázquez, I K

2012-01-01

Lung perfusion scintigraphy (LPS) with (99m)Tc-MAA gives valuable information about patients who will undergo a single lung transplantation. This technique makes it possible to evaluate and quantify the relative function of both lungs to select the organ to be transplanted. Once the surgery has been performed, the LPS represents a diagnostic method to study the status of the transplanted organ. Two patients who underwent single lung transplantation were studied in our hospital. In both cases, a pre-operative LPS was performed before surgery for selection of the organ to be transplanted and the scintigraphy study was performed a few months after transplantation to establish the perfusion function of the transplanted lung. Copyright © 2011 Elsevier España, S.L. y SEMNIM. All rights reserved.

Stochastic rat lung dosimetry for inhaled radon progeny: a surrogate for the human lung for lung cancer risk assessment.

PubMed

Winkler-Heil, R; Hussain, M; Hofmann, W

2015-05-01

Laboratory rats are frequently used in inhalation studies as a surrogate for human exposures. The objective of the present study was therefore to develop a stochastic dosimetry model for inhaled radon progeny in the rat lung, to predict bronchial dose distributions and to compare them with corresponding dose distributions in the human lung. The most significant difference between human and rat lungs is the branching structure of the bronchial tree, which is relatively symmetric in the human lung, but monopodial in the rat lung. Radon progeny aerosol characteristics used in the present study encompass conditions typical for PNNL and COGEMA rat inhalation studies, as well as uranium miners and human indoor exposure conditions. It is shown here that depending on exposure conditions and modeling assumptions, average bronchial doses in the rat lung ranged from 5.4 to 7.3 mGy WLM(-1). If plotted as a function of airway generation, bronchial dose distributions exhibit a significant maximum in large bronchial airways. If, however, plotted as a function of airway diameter, then bronchial doses are much more uniformly distributed throughout the bronchial tree. Comparisons between human and rat exposures indicate that rat bronchial doses are slightly higher than human bronchial doses by about a factor of 1.3, while lung doses, averaged over the bronchial (BB), bronchiolar (bb) and alveolar-interstitial (AI) regions, are higher by about a factor of about 1.6. This supports the current view that the rat lung is indeed an appropriate surrogate for the human lung in case of radon-induced lung cancers. Furthermore, airway diameter seems to be a more appropriate morphometric parameter than airway generations to relate bronchial doses to bronchial carcinomas.

Staging of Lung Cancer

MedlinePlus

... LUNG CANCER MINI-SERIES #2 Staging of Lung Cancer Once your lung cancer is diagnosed, staging tells you and your health care provider about ... at it under a microscope. The stages of lung cancer are listed as I, II, III, and IV ...

Overview of Clinical Lung Transplantation

PubMed Central

Yeung, Jonathan C.; Keshavjee, Shaf

2014-01-01

Since the first successful lung transplant 30 years ago, lung transplantation has rapidly become an established standard of care to treat end-stage lung disease in selected patients. Advances in lung preservation, surgical technique, and immunosuppression regimens have resulted in the routine performance of lung transplantation around the world for an increasing number of patients, with wider indications. Despite this, donor shortages and chronic lung allograft dysfunction continue to prevent lung transplantation from reaching its full potential. With research into the underlying mechanisms of acute and chronic lung graft dysfunction and advances in personalized diagnostic and therapeutic approaches to both the donor lung and the lung transplant recipient, there is increasing confidence that we will improve short- and long-term outcomes in the near future. PMID:24384816

MRI and CT lung biomarkers: Towards an in vivo understanding of lung biomechanics.

PubMed

Young, Heather M; Eddy, Rachel L; Parraga, Grace

2017-09-29

The biomechanical properties of the lung are necessarily dependent on its structure and function, both of which are complex and change over time and space. This makes in vivo evaluation of lung biomechanics and a deep understanding of lung biomarkers, very challenging. In patients and animal models of lung disease, in vivo evaluations of lung structure and function are typically made at the mouth and include spirometry, multiple-breath gas washout tests and the forced oscillation technique. These techniques, and the biomarkers they provide, incorporate the properties of the whole organ system including the parenchyma, large and small airways, mouth, diaphragm and intercostal muscles. Unfortunately, these well-established measurements mask regional differences, limiting their ability to probe the lung's gross and micro-biomechanical properties which vary widely throughout the organ and its subcompartments. Pulmonary imaging has the advantage in providing regional, non-invasive measurements of healthy and diseased lung, in vivo. Here we summarize well-established and emerging lung imaging tools and biomarkers and how they may be used to generate lung biomechanical measurements. We review well-established and emerging lung anatomical, microstructural and functional imaging biomarkers generated using synchrotron x-ray tomographic-microscopy (SRXTM), micro-x-ray computed-tomography (micro-CT), clinical CT as well as magnetic resonance imaging (MRI). Pulmonary imaging provides measurements of lung structure, function and biomechanics with high spatial and temporal resolution. Imaging biomarkers that reflect the biomechanical properties of the lung are now being validated to provide a deeper understanding of the lung that cannot be achieved using measurements made at the mouth. Copyright © 2017 Elsevier Ltd. All rights reserved.

miR-34a Inhibits Lung Fibrosis by Inducing Lung Fibroblast Senescence.

PubMed

Cui, Huachun; Ge, Jing; Xie, Na; Banerjee, Sami; Zhou, Yong; Antony, Veena B; Thannickal, Victor J; Liu, Gang

2017-02-01

Cellular senescence has been implicated in diverse pathologies. However, there is conflicting evidence regarding the role of this process in tissue fibrosis. Although dysregulation of microRNAs is a key mechanism in the pathogenesis of lung fibrosis, it is unclear whether microRNAs function by regulating cellular senescence in the disease. In this study, we found that miR-34a demonstrated greater expression in the lungs of patients with idiopathic pulmonary fibrosis and in mice with experimental pulmonary fibrosis, with its primary localization in lung fibroblasts. More importantly, miR-34a was up-regulated significantly in both human and mouse lung myofibroblasts. We found that mice with miR-34a ablation developed more severe pulmonary fibrosis than did wild-type animals after fibrotic lung injury. Mechanistically, we found that miR-34a induced a senescent phenotype in lung fibroblasts because this microRNA increased senescence-associated β-galactosidase activity, enhanced expression of senescence markers, and decreased cell proliferative capacities. Consistently, we found that primary lung fibroblasts from fibrotic lungs of miR-34a-deficient mice had a diminished senescent phenotype and enhanced resistance to apoptosis as compared with those from wild-type animals. We also identified multiple miR-34a targets that likely mediated its activities in inducing senescence in lung fibroblasts. In conclusion, our data suggest that miR-34a functions through a negative feedback mechanism to restrain fibrotic response in the lungs by promoting senescence of pulmonary fibroblasts.

The concept of "baby lung".

PubMed

Gattinoni, Luciano; Pesenti, Antonio

2005-06-01

The "baby lung" concept originated as an offspring of computed tomography examinations which showed in most patients with acute lung injury/acute respiratory distress syndrome that the normally aerated tissue has the dimensions of the lung of a 5- to 6-year-old child (300-500 g aerated tissue). The respiratory system compliance is linearly related to the "baby lung" dimensions, suggesting that the acute respiratory distress syndrome lung is not "stiff" but instead small, with nearly normal intrinsic elasticity. Initially we taught that the "baby lung" is a distinct anatomical structure, in the nondependent lung regions. However, the density redistribution in prone position shows that the "baby lung" is a functional and not an anatomical concept. This provides a rational for "gentle lung treatment" and a background to explain concepts such as baro- and volutrauma. From a physiological perspective the "baby lung" helps to understand ventilator-induced lung injury. In this context, what appears dangerous is not the V(T)/kg ratio but instead the V(T)/"baby lung" ratio. The practical message is straightforward: the smaller the "baby lung," the greater is the potential for unsafe mechanical ventilation.

Non-Small-Cell Lung Cancer Molecular Signatures Recapitulate Lung Developmental Pathways

PubMed Central

Borczuk, Alain C.; Gorenstein, Lyall; Walter, Kristin L.; Assaad, Adel A.; Wang, Liqun; Powell, Charles A.

2003-01-01

Current paradigms hold that lung carcinomas arise from pleuripotent stem cells capable of differentiation into one or several histological types. These paradigms suggest lung tumor cell ontogeny is determined by consequences of gene expression that recapitulate events important in embryonic lung development. Using oligonucleotide microarrays, we acquired gene profiles from 32 microdissected non-small-cell lung tumors. We determined the 100 top-ranked marker genes for adenocarcinoma, squamous cell, large cell, and carcinoid using nearest neighbor analysis. Results were validated by immunostaining for 11 selected proteins using a tissue microarray representing 80 tumors. Gene expression data of lung development were accessed from a publicly available dataset generated with the murine Mu11k genome microarray. Self-organized mapping identified two temporally distinct clusters of murine orthologues. Supervised clustering of lung development data showed large-cell carcinoma gene orthologues were in a cluster expressed in pseudoglandular and canalicular stages whereas adenocarcinoma homologues were predominantly in a cluster expressed later in the terminal sac and alveolar stages of murine lung development. Representative large-cell genes (E2F3, MYBL2, HDAC2, CDK4, PCNA) are expressed in the nucleus and are associated with cell cycle and proliferation. In contrast, adenocarcinoma genes are associated with lung-specific transcription pathways (SFTPB, TTF-1), cell adhesion, and signal transduction. In sum, non-small-cell lung tumors histology gene profiles suggest mechanisms relevant to ontogeny and clinical course. Adenocarcinoma genes are associated with differentiation and glandular formation whereas large-cell genes are associated with proliferation and differentiation arrest. The identification of developmentally regulated pathways active in tumorigenesis provides insights into lung carcinogenesis and suggests early steps may differ according to the eventual tumor

Lung mass density analysis using deep neural network and lung ultrasound surface wave elastography.

PubMed

Zhou, Boran; Zhang, Xiaoming

2018-05-23

Lung mass density is directly associated with lung pathology. Computed Tomography (CT) evaluates lung pathology using the Hounsfield unit (HU) but not lung density directly. We have developed a lung ultrasound surface wave elastography (LUSWE) technique to measure the surface wave speed of superficial lung tissue. The objective of this study was to develop a method for analyzing lung mass density of superficial lung tissue using a deep neural network (DNN) and synthetic data of wave speed measurements with LUSWE. The synthetic training dataset of surface wave speed, excitation frequency, lung mass density, and viscoelasticity from LUSWE (788,000 in total) was used to train the DNN model. The DNN was composed of 3 hidden layers of 1024 neurons for each layer and trained for 10 epochs with a batch size of 4096 and a learning rate of 0.001 with three types of optimizers. The test dataset (4000) of wave speeds at three excitation frequencies (100, 150, and 200 Hz) and shear elasticity of superficial lung tissue was used to predict the lung density and evaluate its accuracy compared with predefined lung mass densities. This technique was then validated on a sponge phantom experiment. The obtained results showed that predictions matched well with test dataset (validation accuracy is 0.992) and experimental data in the sponge phantom experiment. This method may be useful to analyze lung mass density by using the DNN model together with the surface wave speed and lung stiffness measurements. Copyright © 2018 Elsevier B.V. All rights reserved.

Amebic lung abscess with coexisting lung adenocarcinoma: a unusual case of amebiasis.

PubMed

Zhu, Hailong; Min, Xiangyang; Li, Shuai; Feng, Meng; Zhang, Guofeng; Yi, Xianghua

2014-01-01

Amebic lung abscess with concurrent lung cancer, but without either a liver abscess or amebic colitis, is extremely uncommon. Here, we report a 70-year-old man presenting with pulmonary amebiasis and coexisting lung adenocarcinoma. During his first-time hospitalization, the diagnosis of lung amebiasis was confirmed by morphological observation and PCR in formalin-fixed and paraffin-embedded sediments of pleural effusion. Almost four months later, the patient was readmitted to hospital for similar complaints. On readmission, lung adenocarcinoma was diagnosed by liquid-based sputum cytology and thought to be delayed because coexisting amebic lung abscess. This case demonstrated that sediments of pleural effusion may be used for further pathological examination after routine cytology has shown negative results. At the same time, we concluded that lung cancer may easily go undetected in the patients with pulmonary amebiasis and repetitive evaluation by cytology and imaging follow-up are useful to find potential cancer.

Amebic lung abscess with coexisting lung adenocarcinoma: a unusual case of amebiasis

PubMed Central

Zhu, Hailong; Min, Xiangyang; Li, Shuai; Feng, Meng; Zhang, Guofeng; Yi, Xianghua

2014-01-01

Amebic lung abscess with concurrent lung cancer, but without either a liver abscess or amebic colitis, is extremely uncommon. Here, we report a 70-year-old man presenting with pulmonary amebiasis and coexisting lung adenocarcinoma. During his first-time hospitalization, the diagnosis of lung amebiasis was confirmed by morphological observation and PCR in formalin-fixed and paraffin-embedded sediments of pleural effusion. Almost four months later, the patient was readmitted to hospital for similar complaints. On readmission, lung adenocarcinoma was diagnosed by liquid-based sputum cytology and thought to be delayed because coexisting amebic lung abscess. This case demonstrated that sediments of pleural effusion may be used for further pathological examination after routine cytology has shown negative results. At the same time, we concluded that lung cancer may easily go undetected in the patients with pulmonary amebiasis and repetitive evaluation by cytology and imaging follow-up are useful to find potential cancer. PMID:25550881

Pulmonary atelectasis during low stretch ventilation: "open lung" versus "lung rest" strategy.

PubMed

Fanelli, Vito; Mascia, Luciana; Puntorieri, Valeria; Assenzio, Barbara; Elia, Vincenzo; Fornaro, Giancarlo; Martin, Erica L; Bosco, Martino; Delsedime, Luisa; Fiore, Tommaso; Grasso, Salvatore; Ranieri, V Marco

2009-03-01

Limiting tidal volume (VT) may minimize ventilator-induced lung injury (VILI). However, atelectasis induced by low VT ventilation may cause ultrastructural evidence of cell disruption. Apoptosis seems to be involved as protective mechanisms from VILI through the involvement of mitogen-activated protein kinases (MAPKs). We examined the hypothesis that atelectasis may influence the response to protective ventilation through MAPKs. Prospective randomized study. University animal laboratory. Adult male 129/Sv mice. Isolated, nonperfused lungs were randomized to VILI: VT of 20 mL/kg and positive end-expiratory pressure (PEEP) zero; low stretch/lung rest: VT of 6 mL/kg and 8-10 cm H2O of PEEP; low stretch/open lung: VT of 6 mL/kg, two recruitment maneuvers and 14-16 cm H2O of PEEP. Ventilator settings were adjusted using the stress index. Both low stretch strategies equally blunted the VILI-induced derangement of respiratory mechanics (static volume-pressure curve), lung histology (hematoxylin and eosin), and inflammatory mediators (interleukin-6, macrophage inflammatory protein-2 [enzyme-linked immunosorbent assay], and inhibitor of nuclear factor-kB[Western blot]). VILI caused nuclear swelling and membrane disruption of pulmonary cells (electron microscopy). Few pulmonary cells with chromatin condensation and fragmentation were seen during both low stretch strategies. However, although cell thickness during low stretch/open lung was uniform, low stretch/lung rest demonstrated thickening of epithelial cells and plasma membrane bleb formation. Compared with the low stretch/open lung, low stretch/lung rest caused a significant decrease in apoptotic cells (terminal deoxynucleotidyl transferase mediated deoxyuridine-triphosphatase nick end-labeling) and tissue expression of caspase-3 (Western blot). Both low stretch strategies attenuated the activation of MAPKs. Such reduction was larger during low stretch/open lung than during low stretch/lung rest (p < 0.001). Low stretch

Integrated Design of Basic Training, Practicum and End-of-Course Assignment Modules in the Teacher Training Degree: Perception of University Teachers, Students, and School Teachers

NASA Astrophysics Data System (ADS)

Torremorell, Maria Carme Boqué; de Nicolás, Montserrat Alguacil; Valls, Mercè Pañellas

Teacher training at the Blanquerna Faculty of Psychology and Educational and Sports Sciences (FPCEE), in Barcelona, has a long pedagogical tradition based on teaching innovation. Its educational style is characterised by methods focused on the students' involvement and on close collaboration with teaching practice centres. Within a core subject in the Teacher Training diploma course, students were asked to assess different methodological proposals aimed at promoting the development of their personal, social, and professional competences. In the assessment surveys, from a sample of 145 students, scores for variables very satisfactory or satisfactory ranged from 95.8 % to 83.4 % for the entire set of methodological actions under analysis. Data obtained in this first research phase were very useful to design basic training modules for the new Teacher Training Degree. In the second phase (in process), active teachers are asked for their perception on the orientation of the practicum, its connection with the end-of-course assignment, and the in-service student's incidence on innovation processes at school.

Live Imaging of the Lung

PubMed Central

Looney, Mark R.; Bhattacharya, Jahar

2015-01-01

Live lung imaging has spanned the discovery of capillaries in the frog lung by Malpighi to the current use of single and multiphoton imaging of intravital and isolated perfused lung preparations incorporating fluorescent molecular probes and transgenic reporter mice. Along the way, much has been learned about the unique microcirculation of the lung, including immune cell migration and the mechanisms by which cells at the alveolar-capillary interface communicate with each other. In this review, we highlight live lung imaging techniques as applied to the role of mitochondria in lung immunity, mechanisms of signal transduction in lung compartments, studies on the composition of alveolar wall liquid, and neutrophil and platelet trafficking in the lung under homeostatic and inflammatory conditions. New applications of live lung imaging and the limitations of current techniques are discussed. PMID:24245941

Neonatal lungs: maturational changes in lung resistivity spectra.

PubMed

Brown, B H; Primhak, R A; Smallwood, R H; Milnes, P; Narracott, A J; Jackson, M J

2002-09-01

The electrical resistivity of lung tissue can be related to the structure and composition of the tissue and also to the air content. Electrical impedance tomographic measurements have been used on 155 normal children over the first three years of life and 25 pre-term infants, to determine the absolute resistivity of lung tissue as a function of frequency. The results show consistent changes with increasing age in both lung tissue resistivity (5.8 ohm m at birth to 20.9 ohm m at 3 years of age) and in the changes of resistivity with frequency (Cole parameter ratio R/S=0.41 at birth and 0.84 at 3 years of age). Comparison with a lung model showed that the measurements are consistent with maturational changes in the number and size of alveoli, the extracapillary blood volume and the size of the extracapillary vessels. However, the results show that the process of maturation is not complete at the age of three years.

Human Lung Fibroblasts Present Bacterial Antigens to Autologous Lung Th Cells.

PubMed

Hutton, Andrew J; Polak, Marta E; Spalluto, C Mirella; Wallington, Joshua C; Pickard, Chris; Staples, Karl J; Warner, Jane A; Wilkinson, Tom M A

2017-01-01

Lung fibroblasts are key structural cells that reside in the submucosa where they are in contact with large numbers of CD4 + Th cells. During severe viral infection and chronic inflammation, the submucosa is susceptible to bacterial invasion by lung microbiota such as nontypeable Haemophilus influenzae (NTHi). Given their proximity in tissue, we hypothesized that human lung fibroblasts play an important role in modulating Th cell responses to NTHi. We demonstrate that fibroblasts express the critical CD4 + T cell Ag-presentation molecule HLA-DR within the human lung, and that this expression can be recapitulated in vitro in response to IFN-γ. Furthermore, we observed that cultured lung fibroblasts could internalize live NTHi. Although unable to express CD80 and CD86 in response to stimulation, fibroblasts expressed the costimulatory molecules 4-1BBL, OX-40L, and CD70, all of which are related to memory T cell activation and maintenance. CD4 + T cells isolated from the lung were predominantly (mean 97.5%) CD45RO + memory cells. Finally, cultured fibroblasts activated IFN-γ and IL-17A cytokine production by autologous, NTHi-specific lung CD4 + T cells, and cytokine production was inhibited by a HLA-DR blocking Ab. These results indicate a novel role for human lung fibroblasts in contributing to responses against bacterial infection through activation of bacteria-specific CD4 + T cells. Copyright © 2016 by The American Association of Immunologists, Inc.

Pediatric lung transplantation

PubMed Central

2017-01-01

Pediatric lung transplantation has been undertaken since the 1980s, and it is today considered an accepted therapy option in carefully selected children with end-stage pulmonary diseases, providing carefully selected children a net survival benefit and improved health-related quality of life. Nowadays, >100 pediatric lung transplants are done worldwide every year. Here, specific pediatric aspects of lung transplantation are reviewed such as the surgical challenge, effects of immunosuppression on the developing pediatric immune system, and typical infections of childhood, as it is vital to comprehend that children undergoing lung transplants present a real challenge as children are not ‘just small adults’. Further, an update on the management of the pediatric lung transplant patient is provided in this review, and future challenges outlined. Indications for lung transplantation in children are different compared to adults, the most common being cystic fibrosis (CF). However, the primary diagnoses leading to pediatric lung transplantation vary considerably by age group. Furthermore, there are regional differences regarding the primary indication for lung transplantation in children. Overall, early referral, careful patient selection and appropriate timing of listing are crucial to achieve real survival benefit. Although allograft function is to be preserved, immunosuppressant-related side effects are common in children post-transplantation. Strategies need to be put into practice to reduce drug-related side effects through careful therapeutic drug monitoring and lowering of target levels of immunosuppression, to avoid acute-reversible and chronic-irreversible renal damage. Instead of a “one fits all approach”, tailored immunosuppression and a personalized therapy is to be advocated, particularly in children. Further, infectious complications are a common in children of all ages, accounting for almost 50% of death in the first year post

Unexpandable lung.

PubMed

Pereyra, Marco F; Ferreiro, Lucía; Valdés, Luis

2013-02-01

Unexpandable lung is a mechanical complication by which the lung does not expand to the chest wall, impeding a normal apposition between the two pleural layers. The main mechanism involved is the restriction of the visceral pleura due to the formation of a fibrous layer along this pleural membrane. This happens because of the presence of an active pleural disease (lung entrapment), which can be resolved if proper therapeutic measures are taken, or a remote disease (trapped lung), in which an irreversible fibrous pleural layer has been formed. The clinical suspicion arises with the presence of post-thoracocentesis hydropneumothorax or a pleural effusion that cannot be drained due to the appearance of thoracic pain. The diagnosis is based on the analysis of the pleural liquid, the determination of pleural pressures as we drain the effusion and on air-contrast chest CT. As both represent the continuity of one same process, the results will depend on the time at which these procedures are done. If, when given a lung that is becoming entrapped, the necessary therapeutic measures are not taken, the final result will be a trapped lung. In this instance, most patients are asymptomatic or have mild exertional dyspnea and therefore they do not require treatment. Nevertheless, in cases of incapacitating dyspnea, it may be necessary to use pleural decortication in order to resolve the symptoms. Copyright © 2012 SEPAR. Published by Elsevier Espana. All rights reserved.

Epidemiology of Lung Cancer.

PubMed

Schwartz, Ann G; Cote, Michele L

2016-01-01

Lung cancer continues to be one of the most common causes of cancer death despite understanding the major cause of the disease: cigarette smoking. Smoking increases lung cancer risk 5- to 10-fold with a clear dose-response relationship. Exposure to environmental tobacco smoke among nonsmokers increases lung cancer risk about 20%. Risks for marijuana and hookah use, and the new e-cigarettes, are yet to be consistently defined and will be important areas for continued research as use of these products increases. Other known environmental risk factors include exposures to radon, asbestos, diesel, and ionizing radiation. Host factors have also been associated with lung cancer risk, including family history of lung cancer, history of chronic obstructive pulmonary disease and infections. Studies to identify genes associated with lung cancer susceptibility have consistently identified chromosomal regions on 15q25, 6p21 and 5p15 associated with lung cancer risk. Risk prediction models for lung cancer typically include age, sex, cigarette smoking intensity and/or duration, medical history, and occupational exposures, however there is not yet a risk prediction model currently recommended for general use. As lung cancer screening becomes more widespread, a validated model will be needed to better define risk groups to inform screening guidelines.

Angiogenin and vascular endothelial growth factor expression in lungs of lung cancer patients.

PubMed

Rozman, Ales; Silar, Mira; Kosnik, Mitja

2012-12-01

BACKGROUND.: Lung cancer is the leading cause of cancer deaths. Angiogenesis is crucial process in cancer growth and progression. This prospective study evaluated expression of two central regulatory molecules: angiogenin and vascular endothelial growth factor (VEGF) in patients with lung cancer. PATIENTS AND METHODS.: Clinical data, blood samples and broncho-alveolar lavage (BAL) from 23 patients with primary lung carcinoma were collected. BAL fluid was taken from part of the lung with malignancy, and from corresponding healthy side of the lung. VEGF and angiogenin concentrations were analysed by an enzyme-linked immunosorbent assay. Dilution of bronchial secretions in the BAL fluid was calculated from urea concentration ratio between serum and BAL fluid. RESULTS.: We found no statistical correlation between angiogenin concentrations in serum and in bronchial secretions from both parts of the lung. VEGF concentrations were greater in bronchial secretions in the affected side of the lung than on healthy side. Both concentrations were greater than serum VEGF concentration. VEGF concentration in serum was in positive correlation with tumour size (p = 0,003) and with metastatic stage of disease (p = 0,041). There was correlation between VEGF and angiogenin concentrations in bronchial secretions from healthy side of the lung and between VEGF and angiogenin concentrations in bronchial secretions from part of the lung with malignancy. CONCLUSION.: Angiogenin and VEGF concentrations in systemic, background and local samples of patients with lung cancer are affected by different mechanisms. Pro-angiogenic activity of lung cancer has an important influence on the levels of angiogenin and VEGF.

Angiogenin and vascular endothelial growth factor expression in lungs of lung cancer patients

PubMed Central

Rozman, Ales; Silar, Mira; Kosnik, Mitja

2012-01-01

Background. Lung cancer is the leading cause of cancer deaths. Angiogenesis is crucial process in cancer growth and progression. This prospective study evaluated expression of two central regulatory molecules: angiogenin and vascular endothelial growth factor (VEGF) in patients with lung cancer. Patients and methods. Clinical data, blood samples and broncho-alveolar lavage (BAL) from 23 patients with primary lung carcinoma were collected. BAL fluid was taken from part of the lung with malignancy, and from corresponding healthy side of the lung. VEGF and angiogenin concentrations were analysed by an enzyme-linked immunosorbent assay. Dilution of bronchial secretions in the BAL fluid was calculated from urea concentration ratio between serum and BAL fluid. Results. We found no statistical correlation between angiogenin concentrations in serum and in bronchial secretions from both parts of the lung. VEGF concentrations were greater in bronchial secretions in the affected side of the lung than on healthy side. Both concentrations were greater than serum VEGF concentration. VEGF concentration in serum was in positive correlation with tumour size (p = 0,003) and with metastatic stage of disease (p = 0,041). There was correlation between VEGF and angiogenin concentrations in bronchial secretions from healthy side of the lung and between VEGF and angiogenin concentrations in bronchial secretions from part of the lung with malignancy. Conclusion. Angiogenin and VEGF concentrations in systemic, background and local samples of patients with lung cancer are affected by different mechanisms. Pro-angiogenic activity of lung cancer has an important influence on the levels of angiogenin and VEGF. PMID:23412843

Lung Focused Resuscitation at a Specialized Donor Care Facility Improves Lung Procurement Rates.

PubMed

Chang, Stephanie H; Kreisel, Daniel; Marklin, Gary F; Cook, Lindsey; Hachem, Ramsey; Kozower, Benjamin D; Balsara, Keki R; Bell, Jennifer M; Frederiksen, Christine; Meyers, Bryan F; Patterson, G Alexander; Puri, Varun

2018-05-01

Lung procurement for transplantation occurs in approximately 20% of brain dead donors and is a major impediment to wider application of lung transplantation. We investigated the effect of lung protective management at a specialized donor care facility on lung procurement rates from brain dead donors. Our local organ procurement organization instituted a protocol of lung protective management at a freestanding specialized donor care facility in 2008. Brain dead donors from 2001 to 2007 (early period) were compared with those from 2009 to 2016 (current period) for lung procurement rates and other solid-organ procurement rates using a prospectively maintained database. An overall increase occurred in the number of brain dead donors during the study period (early group, 791; late group, 1,333; p < 0.0001). The lung procurement rate (lung donors/all brain dead donors) improved markedly after the introduction of lung protective management (early group, 157 of 791 [19.8%]; current group, 452 of 1,333 [33.9%]; p < 0.0001). The overall organ procurement rate (total number of organs procured/donor) also increased during the study period (early group, 3.5 organs/donor; current group, 3.8 organs/donor; p = 0.006). Lung protective management in brain dead donors at a specialized donor care facility is associated with higher lung utilization rates compared with conventional management. This strategy does not adversely affect the utilization of other organs in a multiorgan donor. Copyright © 2018 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

Variable tidal volumes improve lung protective ventilation strategies in experimental lung injury.

PubMed

Spieth, Peter M; Carvalho, Alysson R; Pelosi, Paolo; Hoehn, Catharina; Meissner, Christoph; Kasper, Michael; Hübler, Matthias; von Neindorff, Matthias; Dassow, Constanze; Barrenschee, Martina; Uhlig, Stefan; Koch, Thea; de Abreu, Marcelo Gama

2009-04-15

Noisy ventilation with variable Vt may improve respiratory function in acute lung injury. To determine the impact of noisy ventilation on respiratory function and its biological effects on lung parenchyma compared with conventional protective mechanical ventilation strategies. In a porcine surfactant depletion model of lung injury, we randomly combined noisy ventilation with the ARDS Network protocol or the open lung approach (n = 9 per group). Respiratory mechanics, gas exchange, and distribution of pulmonary blood flow were measured at intervals over a 6-hour period. Postmortem, lung tissue was analyzed to determine histological damage, mechanical stress, and inflammation. We found that, at comparable minute ventilation, noisy ventilation (1) improved arterial oxygenation and reduced mean inspiratory peak airway pressure and elastance of the respiratory system compared with the ARDS Network protocol and the open lung approach, (2) redistributed pulmonary blood flow to caudal zones compared with the ARDS Network protocol and to peripheral ones compared with the open lung approach, (3) reduced histological damage in comparison to both protective ventilation strategies, and (4) did not increase lung inflammation or mechanical stress. Noisy ventilation with variable Vt and fixed respiratory frequency improves respiratory function and reduces histological damage compared with standard protective ventilation strategies.

Indium Lung Disease

PubMed Central

Nakano, Makiko; Omae, Kazuyuki; Takeuchi, Koichiro; Chonan, Tatsuya; Xiao, Yong-long; Harley, Russell A.; Roggli, Victor L.; Hebisawa, Akira; Tallaksen, Robert J.; Trapnell, Bruce C.; Day, Gregory A.; Saito, Rena; Stanton, Marcia L.; Suarthana, Eva; Kreiss, Kathleen

2012-01-01

Background: Reports of pulmonary fibrosis, emphysema, and, more recently, pulmonary alveolar proteinosis (PAP) in indium workers suggested that workplace exposure to indium compounds caused several different lung diseases. Methods: To better understand the pathogenesis and natural history of indium lung disease, a detailed, systematic, multidisciplinary analysis of clinical, histopathologic, radiologic, and epidemiologic data for all reported cases and workplaces was undertaken. Results: Ten men (median age, 35 years) who produced, used, or reclaimed indium compounds were diagnosed with interstitial lung disease 4-13 years after first exposure (n = 7) or PAP 1-2 years after first exposure (n = 3). Common pulmonary histopathologic features in these patients included intraalveolar exudate typical of alveolar proteinosis (n = 9), cholesterol clefts and granulomas (n = 10), and fibrosis (n = 9). Two patients with interstitial lung disease had pneumothoraces. Lung disease progressed following cessation of exposure in most patients and was fatal in two. Radiographic data revealed that two patients with PAP subsequently developed fibrosis and one also developed emphysematous changes. Epidemiologic investigations demonstrated the potential for exposure to respirable particles and an excess of lung abnormalities among coworkers. Conclusions: Occupational exposure to indium compounds was associated with PAP, cholesterol ester crystals and granulomas, pulmonary fibrosis, emphysema, and pneumothoraces. The available evidence suggests exposure to indium compounds causes a novel lung disease that may begin with PAP and progress to include fibrosis and emphysema, and, in some cases, premature death. Prospective studies are needed to better define the natural history and prognosis of this emerging lung disease and identify effective prevention strategies. PMID:22207675

Cervical lung hernia

PubMed Central

Lightwood, Robin G.; Cleland, W. P.

1974-01-01

Lightwood, R. G., and Cleland, W. P. (1974).Thorax, 29, 349-351. Cervical lung hernia. Lung hernias occur in the cervical position in about one third of cases. The remainder appear through the chest wall. Some lung hernias are congenital, but trauma is the most common cause. The indications for surgery depend upon the severity of symptoms. Repair by direct suture can be used for small tears in Sibson's (costovertebral) fascia while larger defects have been closed using prosthetic materials. Four patients with cervical lung hernia are described together with an account of their operations. PMID:4850946

Surgical lung biopsy in transplant patients with diffuse lung disease: how much worse when the lung is the graft?

PubMed

Bertolotti, Alejandro; Defranchi, Sebastián; Vigliano, Carlos; Haberman, Diego; Favaloro, Roberto

2013-07-01

There are no data that compare the clinical presentation and results of surgical lung biopsy (SLB) for diffuse lung disease (DLD) in lung transplant patients, in contrast to individuals with other type of solid organ grafts. Our objective was to compare the clinical picture, radiologic pattern, pathology results, and outcomes of SLB for DLD in these two subsets of patients. We retrospectively reviewed the clinical records of transplant patients undergoing SLB for DLD at our institution between 2004 and 2011. Patients with lung transplants and those with other transplants were compared. During the study period, 1,232 solid organ transplants were done at our institution. Of these, 49 patients (4%) had DLD that needed SLB for diagnosis, and 24 of these patients had a lung transplant. Dyspnea and a radiologic reticular pattern were more frequent in lung transplant patients, 21 of 24 vs 11 of 25 (p = 0.001) and 14 of 24 vs 7 of 25 (p = 0.03), respectively. Although postoperative complications and in-hospital deaths were more common in lung transplant patients, the differences were not statistically significant. Having the SLB performed for diagnosis, as opposed to being conducted for DLD that did not improve on medical treatment, had a protective effect on multivariate analysis (hazard ratio, 0.39; 95% confidence interval, 0.16 to 0.96; p = 0.042). A prior lung transplant was the only independent predictor of survival (hazard ratio, 4.62; 95% confidence interval, 1.53 to 13.92, p = 0.006). It is relatively uncommon for a solid organ transplant patient with DLD to require a SLB. Clinical and radiologic presentation differ in patients with lung transplants compared with other transplants. Postoperative outcomes are not significantly different between the groups. SLB performed early in the course of the disease might be beneficial. Having a lung transplant is a significant negative predictor of survival. Copyright © 2013 The Society of Thoracic Surgeons. Published by

Influence of Pulmonary Rehabilitation on Lung Function Changes After the Lung Resection for Primary Lung Cancer in Patients with Chronic Obstructive Pulmonary Disease.

PubMed

Mujovic, Natasa; Mujovic, Nebojsa; Subotic, Dragan; Ercegovac, Maja; Milovanovic, Andjela; Nikcevic, Ljubica; Zugic, Vladimir; Nikolic, Dejan

2015-11-01

Influence of physiotherapy on the outcome of the lung resection is still controversial. Study aim was to assess the influence of physiotherapy program on postoperative lung function and effort tolerance in lung cancer patients with chronic obstructive pulmonary disease (COPD) that are undergoing lobectomy or pneumonectomy. The prospective study included 56 COPD patients who underwent lung resection for primary non small-cell lung cancer after previous physiotherapy (Group A) and 47 COPD patients (Group B) without physiotherapy before lung cancer surgery. In Group A, lung function and effort tolerance on admission were compared with the same parameters after preoperative physiotherapy. Both groups were compared in relation to lung function, effort tolerance and symptoms change after resection. In patients with tumors requiring a lobectomy, after preoperative physiotherapy, a highly significant increase in FEV1, VC, FEF50 and FEF25 of 20%, 17%, 18% and 16% respectively was registered with respect to baseline values. After physiotherapy, a significant improvement in 6-minute walking distance was achieved. After lung resection, the significant loss of FEV1 and VC occurred, together with significant worsening of the small airways function, effort tolerance and symptomatic status. After the surgery, a clear tendency existed towards smaller FEV1 loss in patients with moderate to severe, when compared to patients with mild baseline lung function impairment. A better FEV1 improvement was associated with more significant loss in FEV1. Physiotherapy represents an important part of preoperative and postoperative treatment in COPD patients undergoing a lung resection for primary lung cancer.

"Open lung ventilation optimizes pulmonary function during lung surgery".

PubMed

Downs, John B; Robinson, Lary A; Steighner, Michael L; Thrush, David; Reich, Richard R; Räsänen, Jukka O

2014-12-01

We evaluated an "open lung" ventilation (OV) strategy using low tidal volumes, low respiratory rate, low FiO2, and high continuous positive airway pressure in patients undergoing major lung resections. In this phase I pilot study, twelve consecutive patients were anesthetized using conventional ventilator settings (CV) and then OV strategy during which oxygenation and lung compliance were noted. Subsequently, a lung resection was performed. Data were collected during both modes of ventilation in each patient, with each patient acting as his own control. The postoperative course was monitored for complications. Twelve patients underwent open thoracotomies for seven lobectomies and five segmentectomies. The OV strategy provided consistent one-lung anesthesia and improved static compliance (40 ± 7 versus 25 ± 4 mL/cm H2O, P = 0.002) with airway pressures similar to CV. Postresection oxygenation (SpO2/FiO2) was better during OV (433 ± 11 versus 386 ± 15, P = 0.008). All postoperative chest x-rays were free of atelectasis or infiltrates. No patient required supplemental oxygen at any time postoperatively or on discharge. The mean hospital stay was 4 ± 1 d. There were no complications or mortality. The OV strategy, previously shown to have benefits during mechanical ventilation of patients with respiratory failure, proved safe and effective in lung resection patients. Because postoperative pulmonary complications may be directly attributable to the anesthetic management, adopting an OV strategy that optimizes lung mechanics and gas exchange may help reduce postoperative problems and improve overall surgical results. A randomized trial is planned to ascertain whether this technique will reduce postoperative pulmonary complications. Copyright © 2014 Elsevier Inc. All rights reserved.

Rebuilding the Injured Lung

PubMed Central

2015-01-01

The 57th annual Thomas L. Petty Aspen Lung Conference, entitled “Rebuilding the Injured Lung,” was held from June 4 to 7, 2014 at the Gant Conference Center in Aspen, Colorado. Investigators from a wide range of disciplines and perspectives convened to discuss the biology of lung injury, how the lung repairs itself, how and why repair fails, and how the repair process can be enhanced. Among the challenges identified in the course of the conference was how to develop more predictive experimental models that capture the multidimensional complexity of lung injury and repair in a tractable manner. From such approaches that successfully fuse the biological and physical sciences, the group envisioned that new therapies for acute and chronic lung injury would emerge. The discussion of experimental therapeutics ranged from pharmaceuticals and cells that interdict fibrosis and enhance repair to a de novo lung derived from stem cells repopulating a decellularized matrix. PMID:25830839

Lung Cancer

MedlinePlus

Lung cancer is one of the most common cancers in the world. It is a leading cause of cancer death in men and women in the United States. Cigarette smoking causes most lung cancers. The more cigarettes you smoke per day and ...

Acute Lung Injury: Making the Injured Lung Perform Better and Rebuilding Healthy Lungs

DTIC Science & Technology

2014-04-01

A. Derivation Lung Mesenchymal Lineages from the Fetal Mesothelium Requires Hedgehog Signaling for Mesothelial Cell Entry. Development 140:4398-4405...mesothelial cell entry into the developing lung are largely unknown. The importance of the hedgehog (Hh) signaling pathway in mesenchymal...et al., 1997; Weaver et al., 2003; Polizio et al., 2011; Yoo et al., 2011). Mammals express three Hh ligands: Indian hedgehog (IHH), desert hedgehog

Substance P receptor blockade decreases stretch-induced lung cytokines and lung injury in rats.

PubMed

Brégeon, Fabienne; Steinberg, Jean Guillaume; Andreotti, Nicolas; Sabatier, Jean-Marc; Delpierre, Stéphane; Ravailhe, Sylvie; Jammes, Yves

2010-04-15

Overdistension of lung tissue during mechanical ventilation causes cytokine release, which may be facilitated by the autonomic nervous system. We used mechanical ventilation to cause lung injury in rats, and studied how cervical section of the vagus nerve, or substance P (SP) antagonism, affected the injury. The effects of 40 or 25 cmH(2)O high airway pressure injurious ventilation (HV(40) and HV(25)) were studied and compared with low airway pressure ventilation (LV) and spontaneous breathing (controls). Lung mechanics, lung weight, gas exchange, lung myeloperoxidase activity, lung concentrations of interleukin (IL)-1 beta and IL-6, and amounts of lung SP were measured. Control rats were intact, others were bivagotomized, and in some animals we administered the neurokinin-1 (NK-1) receptor blocking agent SR140333. We first determined the durations of HV(40) and HV(25) that induced the same levels of lung injury and increased lung contents of IL-1 beta and IL-6. They were 90 min and 120 min, respectively. Both HV(40) and HV(25) increased lung SP, IL-1 beta and IL-6 levels, these effects being markedly reduced by NK-1 receptor blockade. Bivagotomy reduced to a lesser extent the HV(40)- and HV(25)-induced increases in SP but significantly reduced cytokine production. Neither vagotomy nor NK-1 receptor blockade prevented HV(40)-induced lung injury but, in the HV(25) group, they made it possible to maintain lung injury indices close to those measured in the LV group. This study suggests that both neuronal and extra-neuronal SP might be involved in ventilator-induced lung inflammation and injury. NK-1 receptor blockade could be a pharmacological tool to minimize some adverse effects of mechanical ventilation.

Comparison of lung protective ventilation strategies in a rabbit model of acute lung injury.

PubMed

Rotta, A T; Gunnarsson, B; Fuhrman, B P; Hernan, L J; Steinhorn, D M

2001-11-01

To determine the impact of different protective and nonprotective mechanical ventilation strategies on the degree of pulmonary inflammation, oxidative damage, and hemodynamic stability in a saline lavage model of acute lung injury. A prospective, randomized, controlled, in vivo animal laboratory study. Animal research facility of a health sciences university. Forty-six New Zealand White rabbits. Mature rabbits were instrumented with a tracheostomy and vascular catheters. Lavage-injured rabbits were randomized to receive conventional ventilation with either a) low peak end-expiratory pressure (PEEP; tidal volume of 10 mL/kg, PEEP of 2 cm H2O); b) high PEEP (tidal volume of 10 mL/kg, PEEP of 10 cm H2O); c) low tidal volume with PEEP above Pflex (open lung strategy, tidal volume of 6 mL/kg, PEEP set 2 cm H2O > Pflex); or d) high-frequency oscillatory ventilation. Animals were ventilated for 4 hrs. Lung lavage fluid and tissue samples were obtained immediately after animals were killed. Lung lavage fluid was assayed for measurements of total protein, elastase activity, tumor necrosis factor-alpha, and malondialdehyde. Lung tissue homogenates were assayed for measurements of myeloperoxidase activity and malondialdehyde. The need for inotropic support was recorded. Animals that received a lung protective strategy (open lung or high-frequency oscillatory ventilation) exhibited more favorable oxygenation and lung mechanics compared with the low PEEP and high PEEP groups. Animals ventilated by a lung protective strategy also showed attenuation of inflammation (reduced tracheal fluid protein, tracheal fluid elastase, tracheal fluid tumor necrosis factor-alpha, and pulmonary leukostasis). Animals treated with high-frequency oscillatory ventilation had attenuated oxidative injury to the lung and greater hemodynamic stability compared with the other experimental groups. Both lung protective strategies were associated with improved oxygenation, attenuated inflammation, and

A New Objective Technique for Verifying Mesoscale Numerical Weather Prediction Models

NASA Technical Reports Server (NTRS)

Case, Jonathan L.; Manobianco, John; Lane, John E.; Immer, Christopher D.

2003-01-01

This report presents a new objective technique to verify predictions of the sea-breeze phenomenon over east-central Florida by the Regional Atmospheric Modeling System (RAMS) mesoscale numerical weather prediction (NWP) model. The Contour Error Map (CEM) technique identifies sea-breeze transition times in objectively-analyzed grids of observed and forecast wind, verifies the forecast sea-breeze transition times against the observed times, and computes the mean post-sea breeze wind direction and speed to compare the observed and forecast winds behind the sea-breeze front. The CEM technique is superior to traditional objective verification techniques and previously-used subjective verification methodologies because: It is automated, requiring little manual intervention, It accounts for both spatial and temporal scales and variations, It accurately identifies and verifies the sea-breeze transition times, and It provides verification contour maps and simple statistical parameters for easy interpretation. The CEM uses a parallel lowpass boxcar filter and a high-order bandpass filter to identify the sea-breeze transition times in the observed and model grid points. Once the transition times are identified, CEM fits a Gaussian histogram function to the actual histogram of transition time differences between the model and observations. The fitted parameters of the Gaussian function subsequently explain the timing bias and variance of the timing differences across the valid comparison domain. Once the transition times are all identified at each grid point, the CEM computes the mean wind direction and speed during the remainder of the day for all times and grid points after the sea-breeze transition time. The CEM technique performed quite well when compared to independent meteorological assessments of the sea-breeze transition times and results from a previously published subjective evaluation. The algorithm correctly identified a forecast or observed sea-breeze occurrence

Lungs and Respiratory System

MedlinePlus

... Videos for Educators Search English Español Lungs and Respiratory System KidsHealth / For Teens / Lungs and Respiratory System ... didn't breathe, you couldn't live. Lungs & Respiratory System Basics Each day we breathe about 20, ...

Down-regulation of lung Kruppel-like factor in the nitrofen-induced hypoplastic lung.

PubMed

Lukošiūtė, A; Doi, T; Dingemann, J; Ruttenstock, E M; Puri, P

2011-01-01

Pulmonary hypoplasia is a primary cause of high morbidity and mortality in neonates with Congenital Diaphragmatic Hernia (CDH). However, the precise pathogenesis of PH associated with CDH is still not clearly understood. It has been recently reported that lung Kruppel-like factor (LKLF), a member of the Kruppel-like factor family of transcription factors, is predominantly expressed in lungs and plays an important role in lung morphogenesis and functional maturation. It has been reported that homozygous deletion of LKLF gene in mice results in reduced lung morphogenesis. It is further reported that chimeric mice derived from LKLF (-/-) embryonic stem cells exhibit delayed lung development especially in the later gestational stages. We therefore designed this study to test the hypothesis that the LKLF gene is down-regulated during later stages of lung development in nitrofen-induced hypoplastic lungs. Pregnant rats were exposed to either olive oil or nitrofen on day 9 of gestation (D9). Fetal lungs were harvested on D15, D18, and D21 and divided into 3 groups:control, nitrofen without CDH(CDH(-)) and nitrofen with CDH(CDH(+)) (n=24 for each group). Real-time RT-PCR analysis was performed to investigate pulmonary gene expression levels of LKLF. Differences between the 3 groups at each time point were tested statistically and significance was accepted at p<0.05. Immunohistochemistry was also performed to evaluate LKLF protein expression and distribution. The relative mRNA expression levels of LKLF on D18 and D21 were significantly decreased (p<0.01) in CDH(-) and CDH(+) groups compared to controls. The gene expression levels of LKLF on D15 did not differ significantly between the nitrofen group and controls. Immunohistochemical study showed strong LKLF immunoreactivity on D18 and D21 in nitrofen-induced hypoplastic lung compared to controls, whereas no difference was seen on D15. Our results provide evidence for the first time that LKLF is down-regulated in the later

Estimation of Lung Ventilation

NASA Astrophysics Data System (ADS)

Ding, Kai; Cao, Kunlin; Du, Kaifang; Amelon, Ryan; Christensen, Gary E.; Raghavan, Madhavan; Reinhardt, Joseph M.

Since the primary function of the lung is gas exchange, ventilation can be interpreted as an index of lung function in addition to perfusion. Injury and disease processes can alter lung function on a global and/or a local level. MDCT can be used to acquire multiple static breath-hold CT images of the lung taken at different lung volumes, or with proper respiratory control, 4DCT images of the lung reconstructed at different respiratory phases. Image registration can be applied to this data to estimate a deformation field that transforms the lung from one volume configuration to the other. This deformation field can be analyzed to estimate local lung tissue expansion, calculate voxel-by-voxel intensity change, and make biomechanical measurements. The physiologic significance of the registration-based measures of respiratory function can be established by comparing to more conventional measurements, such as nuclear medicine or contrast wash-in/wash-out studies with CT or MR. An important emerging application of these methods is the detection of pulmonary function change in subjects undergoing radiation therapy (RT) for lung cancer. During RT, treatment is commonly limited to sub-therapeutic doses due to unintended toxicity to normal lung tissue. Measurement of pulmonary function may be useful as a planning tool during RT planning, may be useful for tracking the progression of toxicity to nearby normal tissue during RT, and can be used to evaluate the effectiveness of a treatment post-therapy. This chapter reviews the basic measures to estimate regional ventilation from image registration of CT images, the comparison of them to the existing golden standard and the application in radiation therapy.

The impact of lungs from diabetic donors on lung transplant recipients†.

PubMed

Ambur, Vishnu; Taghavi, Sharven; Jayarajan, Senthil; Kadakia, Sagar; Zhao, Huaqing; Gomez-Abraham, Jesus; Toyoda, Yoshiya

2017-02-01

We attempted to determine if transplants of lungs from diabetic donors (DDs) is associated with increased mortality of recipients in the modern era of the lung allocation score (LAS). The United Network for Organ Sharing (UNOS) database was queried for all adult lung transplant recipients from 2006 to 2014. Patients receiving a lung from a DD were compared to those receiving a transplant from a non-DD. Multivariate Cox regression analysis using variables associated with mortality was used to examine survival. A total of 13 159 adult lung transplants were performed between January 2006 and June 2014: 4278 (32.5%) were single-lung transplants (SLT) and 8881 (67.5%) were double-lung transplants (DLT). The log-rank test demonstrated a lower median survival in the DD group (5.6 vs 5.0 years, P = 0.003). We performed additional analysis by dividing this initial cohort into two cohorts by transplant type. On multivariate analysis, receiving an SLT from a DD was associated with increased mortality (HR 1.28, 95% CI 1.07–1.54, P = 0.011). Interestingly, multivariate analysis demonstrated no difference in mortality rates for patients receiving a DLT from a DD (HR 1.12, 95% CI 0.97–1.30, P = 0.14). DLT with DDs can be performed safely without increased mortality, but SLT using DDs results in worse survival and post-transplant outcomes. Preference should be given to DLT when using lungs from donors with diabetes. © The Author 2016. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.

The lung in space.

PubMed

Prisk, G Kim

2005-09-01

The lung is exquisitely sensitive to gravity, which induces gradients in ventilation, blood flow, and gas exchange. Studies of lungs in microgravity provide a means of elucidating the effects of gravity. They suggest a mechanism by which gravity serves to match ventilation to perfusion, making for a more efficient lung than anticipated. Despite predictions, lungs do not become edematous, and there is no disruption to, gas exchange in microgravity. Sleep disturbances in microgravity are not a result of respiratory-related events; obstructive sleep apnea is caused principally by the gravitational effects on the upper airways. In microgravity, lungs may be at greater risk to the effects of inhaled aerosols.

The lung in space

NASA Technical Reports Server (NTRS)

Prisk, G. Kim

2005-01-01

The lung is exquisitely sensitive to gravity, which induces gradients in ventilation, blood flow, and gas exchange. Studies of lungs in microgravity provide a means of elucidating the effects of gravity. They suggest a mechanism by which gravity serves to match ventilation to perfusion, making for a more efficient lung than anticipated. Despite predictions, lungs do not become edematous, and there is no disruption to, gas exchange in microgravity. Sleep disturbances in microgravity are not a result of respiratory-related events; obstructive sleep apnea is caused principally by the gravitational effects on the upper airways. In microgravity, lungs may be at greater risk to the effects of inhaled aerosols.

CFTR and lung homeostasis

PubMed Central

Matalon, Sadis

2014-01-01

CFTR is a cAMP-activated chloride and bicarbonate channel that is critical for lung homeostasis. Decreases in CFTR expression have dire consequences in cystic fibrosis (CF) and have been suggested to be a component of the lung pathology in chronic obstructive pulmonary disease. Decreases or loss of channel function often lead to mucus stasis, chronic bacterial infections, and the accompanying chronic inflammatory responses that promote progressive lung destruction, and, eventually in CF, lung failure. Here we discuss CFTR's functional role airway surface liquid hydration and pH, in regulation of other channels such as the epithelial sodium channel, and in regulating inflammatory responses in the lung. PMID:25381027

WHAT MAKES A GOOD PEDIATRIC TRANSPLANT LUNG: INSIGHTS FROM IN VIVO LUNG MORPHOMETRY WITH HYPERPOLARIZED 3HE MRI (WHAT MAKES A GOOD PEDIATRIC TRANSPLANT LUNG)

PubMed Central

Fishman, Emily F.; Quirk, James D.; Sweet, Stuart C.; Woods, Jason C.; Gierada, David S.; Conradi, Mark S.; Siegel, Marilyn J.; Yablonskiy, Dmitriy A.

2016-01-01

Background Obtaining information on transplanted lung microstructure is an important part of the current care for monitoring transplant recipients. However, until now this information was only available from invasive lung biopsy. The objective of this study was to evaluate the use of an innovative non-invasive technique in vivo lung morphometry with hyperpolarized 3He MRI - to characterize lung microstructure in the pediatric lung transplant population. This technique yields quantitative measurements of acinar airways’ (alveolar ducts and sacs) parameters, such as acinar airways radii and alveolar depth. Methods Six pediatric lung transplant recipients with cystic fibrosis underwent in vivo lung morphometry MRI, pulmonary function testing, and quantitative CT. Results We found a strong correlation between lung lifespan and alveolar depth - patients with more shallow alveoli were likely to have a negative outcome sooner than those with larger alveolar depth. Combining morphometric results with CT we also determined mean alveolar wall thickness and found substantial increases in this parameter in some patients that negatively correlated with DLCO. Conclusion In vivo lung morphometry uniquely provides previously unavailable information on lung microstructure that may be predictive of a negative outcome and has a potential to aid in lung selection for transplantation. PMID:28120553

Genomic Medicine and Lung Diseases

PubMed Central

Center, David M.; Schwartz, David A.; Solway, Julian; Gail, Dorothy; Laposky, Aaron D.

2012-01-01

The recent explosion of genomic data and technology points to opportunities to redefine lung diseases at the molecular level; to apply integrated genomic approaches to elucidate mechanisms of lung pathophysiology; and to improve early detection, diagnosis, and treatment of lung diseases. Research is needed to translate genomic discoveries into clinical applications, such as detecting preclinical disease, predicting patient outcomes, guiding treatment choices, and most of all identifying potential therapeutic targets for lung diseases. The Division of Lung Diseases in the National Heart, Lung, and Blood Institute convened a workshop, “Genomic Medicine and Lung Diseases,” to discuss the potential for integrated genomics and systems approaches to advance 21st century pulmonary medicine and to evaluate the most promising opportunities for this next phase of genomics research to yield clinical benefit. Workshop sessions included (1) molecular phenotypes, molecular biomarkers, and therapeutics; (2) new technology and opportunity; (3) integrative genomics; (4) molecular anatomy of the lung; (5) novel data and information platforms; and (6) recommendations for exceptional research opportunities in lung genomics research. PMID:22652029

Investigation of local meteorological events and their relationship with ozone and aerosols during an ESCOMPTE photochemical episode

NASA Astrophysics Data System (ADS)

Augustin, P.; Delbarre, H.; Lohou, F.; Campistron, B.; Puygrenier, V.; Cachier, H.; Lombardo, T.

2006-11-01

The international ESCOMPTE campaign, which took place in summer 2001 in the most highly polluted French region, was devoted to validate air pollution prediction models. Surface and remote sensing instruments (Lidar, Radar and Sodar) were deployed over the Marseille area, along the Mediterranean coast, in order to investigate the fine structure of the sea-breeze circulation and its relationship with the pollutant concentrations. The geographical situation of the Marseille region combines a complex coastline and relief which both lead to a peculiar behaviour of the sea-breeze circulation. Several local sea breezes, perpendicular to the nearest coastline, settled in during the morning. In the afternoons, when the thermal gradient between the continental and marine surface grows up, a southerly or a westerly sea breeze may dominate. Their respective importance is then a function of time, space and altitude. Furthermore, an oscillation of the westerly sea breeze with a period of about 3 h is also highlighted. We show that these dynamical characteristics have profound influences on the atmospheric boundary-layer (ABL) development and on pollutant concentrations. In fact, the direction and intensity of the sea-breeze determine the route and the transit time of the stable marine air flow over the continental surface. Thus, the ABL depth may exhibit several collapses correlated with the westerly sea-breeze pulsation. The ozone and aerosol concentrations are also related to the dynamical features. In the suburbs and parts of the city under pulsed sea breezes, a higher ABL depth and higher ozone concentrations are observed. In the city centre, this relationship between pulsed sea-breeze intensity and ozone concentration is different, emphasising the importance of the transit time and also the build-up of pollutants in the marine air mass along the route. Finally, the variations of aerosol concentration are also described according to the breeze direction.

Composition of individual aerosol particles above the Israelian Mediterranean coast during the summer time

NASA Astrophysics Data System (ADS)

Ganor, E.; Levin, Z.; Van Grieken, R.

Aerosol particles were collected aboard a ship in Haifa Bay and Tel Aviv, Israel, during the summer time. The aerosol particles (6170) were analyzed as individual particles and classified according to their chemical composition, size, number concentration per cubic centimeter and morphology. Most of the aerosol particles could be classified into four groups. The first contains gypsum from the sea and from industrial sources brought in by land breezes. A second group is characterized by continental aluminosilicate and quartz. A third group consists of sea salt mixed with sulfate particles. The fourth group is characterized by an abundance of sulfate particles, some of which are ammonium sulfate brought by the land breezes. The particles were identified as marine and mineral aerosols which originated in Eastern Europe and the Mediterranean sea, while local aerosols brought by land breeze characterized by phosphate, fly ash and soil particles originated in the Haifa industrial zone. In addition, the aerosols were analyzed for sulfates and nitrates. Aerosols of sea and land breezes differed as follows: (1) Sulfate and nitrate concentrations in the aerosols were 5-10 times higher during land breeze than during sea breeze, and the total content of suspended particles was, respectively, 6-12 times higher. (2) Particle size spectra during land breeze were broader than during sea breeze and their concentrations were about 20 times greater. Analyses of individual particles by electron microscopy revealed that during the sea breeze the aerosols contained calcium sulfate, sodium sulfate and sulfuric acid. The sulfuric acid, of pH 2.5, is due to the long-range transport as previously reported ( Ganor et al., 1993) while the other sulfates are from the sea. This explains the high concentration of sulfates in the atmospheric sea breeze above the Israelian Mediterranean coast during the summertime.

Preconditioning allows engraftment of mouse and human embryonic lung cells, enabling lung repair in mice.

PubMed

Rosen, Chava; Shezen, Elias; Aronovich, Anna; Klionsky, Yael Zlotnikov; Yaakov, Yasmin; Assayag, Miri; Biton, Inbal Eti; Tal, Orna; Shakhar, Guy; Ben-Hur, Herzel; Shneider, David; Vaknin, Zvi; Sadan, Oscar; Evron, Shmuel; Freud, Enrique; Shoseyov, David; Wilschanski, Michael; Berkman, Neville; Fibbe, Willem E; Hagin, David; Hillel-Karniel, Carmit; Krentsis, Irit Milman; Bachar-Lustig, Esther; Reisner, Yair

2015-08-01

Repair of injured lungs represents a longstanding therapeutic challenge. We show that human and mouse embryonic lung tissue from the canalicular stage of development (20-22 weeks of gestation for humans, and embryonic day 15-16 (E15-E16) for mouse) are enriched with progenitors residing in distinct niches. On the basis of the marked analogy to progenitor niches in bone marrow (BM), we attempted strategies similar to BM transplantation, employing sublethal radiation to vacate lung progenitor niches and to reduce stem cell competition. Intravenous infusion of a single cell suspension of canalicular lung tissue from GFP-marked mice or human fetal donors into naphthalene-injured and irradiated syngeneic or SCID mice, respectively, induced marked long-term lung chimerism. Donor type structures or 'patches' contained epithelial, mesenchymal and endothelial cells. Transplantation of differentially labeled E16 mouse lung cells indicated that these patches were probably of clonal origin from the donor. Recipients of the single cell suspension transplant exhibited marked improvement in lung compliance and tissue damping reflecting the energy dissipation in the lung tissues. Our study provides proof of concept for lung reconstitution by canalicular-stage human lung cells after preconditioning of the pulmonary niche.

Precision cut lung slices as an efficient tool for in vitro lung physio-pharmacotoxicology studies.

PubMed

Morin, Jean-Paul; Baste, Jean-Marc; Gay, Arnaud; Crochemore, Clément; Corbière, Cécile; Monteil, Christelle

2013-01-01

1.We review the specific approaches for lung tissue slices preparation and incubation systems and the research application fields in which lung slices proved to be a very efficient alternative to animal experimentation for biomechanical, physiological, pharmacological and toxicological approaches. 2.Focus is made on air-liquid interface dynamic organ culture systems that allow direct tissue exposure to complex aerosol and that best mimic in vivo lung tissue physiology. 3.A compilation of research applications in the fields of vascular and airway reactivity, mucociliary transport, polyamine transport, xenobiotic biotransformation, chemicals toxicology and complex aerosols supports the concept that precision cut lung slices are a very efficient tool maintaining highly differentiated functions similar to in vivo lung organ when kept under dynamic organ culture. They also have been successfully used for lung gene transfer efficiency assessment, for lung viral infection efficiency assessment, for studies of tissue preservation media and tissue post-conditioning to optimize lung tissue viability before grafting. 4.Taken all together, the reviewed studies point to a great interest for precision cut lung slices as an efficient and valuable alternative to in vivo lung organ experimentation.

Abnormal lung sounds in patients with asthma during episodes with normal lung function.

PubMed

Schreur, H J; Vanderschoot, J; Zwinderman, A H; Dijkman, J H; Sterk, P J

1994-07-01

Even in patients with clinically stable asthma with normal lung function, the airways are characterized by inflammatory changes, including mucosal swelling. In order to investigate whether lung sounds can distinguish these subjects from normal subjects, we compared lung sound characteristics between eight normal and nine symptom-free subjects with mild asthma. All subjects underwent simultaneous recordings of airflow, lung volume changes, and lung sounds during standardized quiet breathing, and during forced maneuvers. Flow-dependent power spectra were computed using fast Fourier transform. For each spectrum we determined lung sound intensity (LSI), frequencies (Q25%, Q50%, Q75%) wheezing (W), and W%. The results were analyzed by ANOVA. During expiration, LSI was lower in patients with asthma than in healthy controls, in particular at relatively low airflow values. During quiet expiration, Q25% to Q75% were higher in asthmatics than in healthy controls, while the change of Q25% to Q75% with flow was greater in asthmatic than in normal subjects. The W and W% were not different between the subject groups. The results indicate that at given airflows, lung sounds are lower in intensity and higher in pitch in asthmatics as compared with controls. This suggests that the generation and/or transmission of lung sounds in symptom-free patients with stable asthma differ from that in normal subjects, even when lung function is within the normal range. Therefore, airflow standardized phonopneumography might reflect morphologic changes in airways of patients with asthma.

Negative pressure ventilation decreases inflammation and lung edema during normothermic ex-vivo lung perfusion.

PubMed

Aboelnazar, Nader S; Himmat, Sayed; Hatami, Sanaz; White, Christopher W; Burhani, Mohamad S; Dromparis, Peter; Matsumura, Nobutoshi; Tian, Ganghong; Dyck, Jason R B; Mengel, Michael; Freed, Darren H; Nagendran, Jayan

2018-04-01

Normothermic ex-vivo lung perfusion (EVLP) using positive pressure ventilation (PPV) and both acellular and red blood cell (RBC)-based perfusate solutions have increased the rate of donor organ utilization. We sought to determine whether a negative pressure ventilation (NPV) strategy would improve donor lung assessment during EVLP. Thirty-two pig lungs were perfused ex vivo for 12 hours in a normothermic state, and were allocated equally to 4 groups according to the mode of ventilation (positive pressure ventilation [PPV] vs NPV) and perfusate composition (acellular vs RBC). The impact of ventilation strategy on the preservation of 6 unutilized human donor lungs was also evaluated. Physiologic parameters, cytokine profiles, lung injury, bullae and edema formation were compared between treatment groups. Perfused lungs demonstrated acceptable oxygenation (partial pressure of arterial oxygen/fraction of inspired oxygen ratio >350 mm Hg) and physiologic parameters. However, there was less generation of pro-inflammatory cytokines (tumor necrosis factor-α, interleukin-6 and interleukin-8) in human and pig lungs perfused, irrespective of perfusate solution used, when comparing NPV with PPV (p < 0.05), and a reduction in bullae formation with an NPV modality (p = 0.02). Pig lungs developed less edema with NPV (p < 0.01), and EVLP using an acellular perfusate solution had greater edema formation, irrespective of ventilation strategy (p = 0.01). Interestingly, human lungs perfused with NPV developed negative edema, or "drying" (p < 0.01), and lower composite acute lung injury (p < 0.01). Utilization of an NPV strategy during extended EVLP is associated with significantly less inflammation, and lung injury, irrespective of perfusate solution composition. Copyright © 2018 International Society for the Heart and Lung Transplantation. Published by Elsevier Inc. All rights reserved.

Estimation of gas and tissue lung volumes by MRI: functional approach of lung imaging.

PubMed

Qanadli, S D; Orvoen-Frija, E; Lacombe, P; Di Paola, R; Bittoun, J; Frija, G

1999-01-01

The purpose of this work was to assess the accuracy of MRI for the determination of lung gas and tissue volumes. Fifteen healthy subjects underwent MRI of the thorax and pulmonary function tests [vital capacity (VC) and total lung capacity (TLC)] in the supine position. MR examinations were performed at inspiration and expiration. Lung volumes were measured by a previously validated technique on phantoms. Both individual and total lung volumes and capacities were calculated. MRI total vital capacity (VC(MRI)) was compared with spirometric vital capacity (VC(SP)). Capacities were correlated to lung volumes. Tissue volume (V(T)) was estimated as the difference between the total lung volume at full inspiration and the TLC. No significant difference was seen between VC(MRI) and VC(SP). Individual capacities were well correlated (r = 0.9) to static volume at full inspiration. The V(T) was estimated to be 836+/-393 ml. This preliminary study demonstrates that MRI can accurately estimate lung gas and tissue volumes. The proposed approach appears well suited for functional imaging of the lung.

Postoperative complications do not influence the pattern of early lung function recovery after lung resection for lung cancer in patients at risk.

PubMed

Ercegovac, Maja; Subotic, Dragan; Zugic, Vladimir; Jakovic, Radoslav; Moskovljevic, Dejan; Bascarevic, Slavisa; Mujovic, Natasa

2014-05-19

The pattern and factors influencing the lung function recovery in the first postoperative days are still not fully elucidated, especially in patients at increased risk. Prospective study on 60 patients at increased risk, who underwent a lung resection for primary lung cancer. complete resection and one or more known risk factors in form of COPD, cardiovascular disorders, advanced age or other comorbidities. Previous myocardial infarction, myocardial revascularization or stenting, cardiac rhythm disorders, arterial hypertension and myocardiopathy determined the increased cardiac risk. The severity of COPD was graded according to GOLD criteria. The trend of the postoperative lung function recovery was assessed by performing spirometry with a portable spirometer. Cardiac comorbidity existed in 55%, mild and moderate COPD in 20% and 35% of patients respectively. Measured values of FVC% and FEV1% on postoperative days one, three and seven, showed continuous improvement, with significant difference between the days of measurement, especially between days three and seven. There was no difference in the trend of the lung function recovery between patients with and without postoperative complications. Whilst pO2 was decreasing during the first three days in a roughly parallel fashion in patients with respiratory, surgical complications and in patients without complications, a slight hypercapnia registered on the first postoperative day was gradually abolished in all groups except in patients with cardiac complications. Extent of the lung resection and postoperative complications do not significantly influence the trend of the lung function recovery after lung resection for lung cancer.

Adverse Heart-Lung Interactions in Ventilator-induced Lung Injury.

PubMed

Katira, Bhushan H; Giesinger, Regan E; Engelberts, Doreen; Zabini, Diana; Kornecki, Alik; Otulakowski, Gail; Yoshida, Takeshi; Kuebler, Wolfgang M; McNamara, Patrick J; Connelly, Kim A; Kavanagh, Brian P

2017-12-01

In the original 1974 in vivo study of ventilator-induced lung injury, Webb and Tierney reported that high Vt with zero positive end-expiratory pressure caused overwhelming lung injury, subsequently shown by others to be due to lung shear stress. To reproduce the lung injury and edema examined in the Webb and Tierney study and to investigate the underlying mechanism thereof. Sprague-Dawley rats weighing approximately 400 g received mechanical ventilation for 60 minutes according to the protocol of Webb and Tierney (airway pressures of 14/0, 30/0, 45/10, 45/0 cm H 2 O). Additional series of experiments (20 min in duration to ensure all animals survived) were studied to assess permeability (n = 4 per group), echocardiography (n = 4 per group), and right and left ventricular pressure (n = 5 and n = 4 per group, respectively). The original Webb and Tierney results were replicated in terms of lung/body weight ratio (45/0 > 45/10 ≈ 30/0 ≈ 14/0; P < 0.05) and histology. In 45/0, pulmonary edema was overt and rapid, with survival less than 30 minutes. In 45/0 (but not 45/10), there was an increase in microvascular permeability, cyclical abolition of preload, and progressive dilation of the right ventricle. Although left ventricular end-diastolic pressure decreased in 45/10, it increased in 45/0. In a classic model of ventilator-induced lung injury, high peak pressure (and zero positive end-expiratory pressure) causes respiratory swings (obliteration during inspiration) in right ventricular filling and pulmonary perfusion, ultimately resulting in right ventricular failure and dilation. Pulmonary edema was due to increased permeability, which was augmented by a modest (approximately 40%) increase in hydrostatic pressure. The lung injury and acute cor pulmonale is likely due to pulmonary microvascular injury, the mechanism of which is uncertain, but which may be due to cyclic interruption and exaggeration of pulmonary blood flow.

The Lung Microbiome, Immunity, and the Pathogenesis of Chronic Lung Disease.

PubMed

O'Dwyer, David N; Dickson, Robert P; Moore, Bethany B

2016-06-15

The development of culture-independent techniques for microbiological analysis has uncovered the previously unappreciated complexity of the bacterial microbiome at various anatomic sites. The microbiome of the lung has relatively less bacterial biomass when compared with the lower gastrointestinal tract yet displays considerable diversity. The composition of the lung microbiome is determined by elimination, immigration, and relative growth within its communities. Chronic lung disease alters these factors. Many forms of chronic lung disease demonstrate exacerbations that drive disease progression and are poorly understood. Mounting evidence supports ways in which microbiota dysbiosis can influence host defense and immunity, and in turn may contribute to disease exacerbations. Thus, the key to understanding the pathogenesis of chronic lung disease may reside in deciphering the complex interactions between the host, pathogen, and resident microbiota during stable disease and exacerbations. In this brief review we discuss new insights into these labyrinthine relationships. Copyright © 2016 by The American Association of Immunologists, Inc.

A Comparative Study of Rat Lung Decellularization by Chemical Detergents for Lung Tissue Engineering

PubMed Central

Tebyanian, Hamid; Karami, Ali; Motavallian, Ebrahim; Aslani, Jafar; Samadikuchaksaraei, Ali; Arjmand, Babak; Nourani, Mohammad Reza

2017-01-01

BACKGROUND: Lung disease is the most common cause of death in the world. The last stage of pulmonary diseases is lung transplantation. Limitation and shortage of donor organs cause to appear tissue engineering field. Decellularization is a hope for producing intact ECM in the development of engineered organs. AIM: The goal of the decellularization process is to remove cellular and nuclear material while retaining lung three-dimensional and molecular proteins. Different concentration of detergents was used for finding the best approach in lung decellularization. MATERIAL AND METHODS: In this study, three-time approaches (24, 48 and 96 h) with four detergents (CHAPS, SDS, SDC and Triton X-100) were used for decellularizing rat lungs for maintaining of three-dimensional lung architecture and ECM protein composition which have significant roles in differentiation and migration of stem cells. This comparative study determined that variable decellularization approaches can cause significantly different effects on decellularized lungs. RESULTS: Results showed that destruction was increased with increasing the detergent concentration. Single detergent showed a significant reduction in maintaining of three-dimensional of lung and ECM proteins (Collagen and Elastin). But, the best methods were mixed detergents of SDC and CHAPS in low concentration in 48 and 96 h decellularization. CONCLUSION: Decellularized lung tissue can be used in the laboratory to study various aspects of pulmonary biology and physiology and also, these results can be used in the continued improvement of engineered lung tissue. PMID:29362610

Impact of a lung transplantation donor-management protocol on lung donation and recipient outcomes.

PubMed

Angel, Luis F; Levine, Deborah J; Restrepo, Marcos I; Johnson, Scott; Sako, Edward; Carpenter, Andrea; Calhoon, John; Cornell, John E; Adams, Sandra G; Chisholm, Gary B; Nespral, Joe; Roberson, Ann; Levine, Stephanie M

2006-09-15

One of the limitations associated with lung transplantation is the lack of available organs. To determine whether a lung donor-management protocol could increase the number of lungs for transplantation without affecting the survival rates of the recipients. We implemented the San Antonio Lung Transplant protocol for managing potential lung donors according to modifications of standard criteria for donor selection and strategies for donor management. We then compared information gathered during a 4-yr period, during which the protocol was used with information gathered during a 4-yr period before protocol implementation. Primary outcome measures were the procurement rate of lungs and the 30-d and 1-yr survival rates of recipients. We reviewed data from 711 potential lung donors. The mean rate of lung procurement was significantly higher (p < 0.0001) during the protocol period (25.5%) than during the pre-protocol period (11.5%), with an estimated risk ratio of 2.2 in favor of the protocol period. More patients received transplants during the protocol period (n = 121) than during the pre-protocol period (n = 53; p < 0.0001). Of 98 actual lung donors during the protocol period, 53 (54%) had initially been considered poor donors; these donors provided 64 (53%) of the 121 lung transplants. The type of donor was not associated with significant differences in recipients' 30-d and 1-yr survival rates or any clinical measures of adequate graft function. The protocol was associated with a significant increase in the number of lung donors and transplant procedures without compromising pulmonary function, length of stay, or survival of the recipients.

How to optimize the lung donor.

PubMed

Sales, Gabriele; Costamagna, Andrea; Fanelli, Vito; Boffini, Massimo; Pugliese, Francesco; Mascia, Luciana; Brazzi, Luca

2018-02-01

Over the last two decades, lung transplantation emerged as the standard of care for patients with advanced and terminal lung disease. Despite the increment in lung transplantation rates, in 2016 the overall mortality while on waiting list in Italy reached 10%, whereas only 39% of the wait-list patients were successfully transplanted. A number of approaches, including protective ventilatory strategy, accurate management of fluid balance, and administration of a hormonal resuscitation therapy, have been reported to improve lung donor performance before organ retrieval. These approaches, in conjunction with the use of ex-vivo lung perfusion technique contributed to expand the lung donor pool, without affecting the harvest of other organs and the outcomes of lung recipients. However, the efficacy of issues related to the ex-vivo lung perfusion technique, such as the optimal ventilation strategy, the ischemia-reperfusion induced lung injury management, the prophylaxis of germs transmission from donor to recipient and the application of targeted pharmacologic therapies to treat specific donor lung injuries are still to be explored. The main objective of the present review is to summarize the "state-of-art" strategies to optimize the donor lungs and to present the actual role of ex-vivo lung perfusion in the process of lung transplant. Moreover, different approaches about the technique reported in literature and several issues that are under investigation to treat specific donor lung injury will be discussed.

First Danish experience with ex vivo lung perfusion of donor lungs before transplantation.

PubMed

Henriksen, Ian Sune Iversen; Møller-Sørensen, Hasse; Møller, Christian Holdfold; Zemtsovski, Mikhail; Nilsson, Jens Christian; Seidelin, Casper Tobias; Perch, Michael; Iversen, Martin; Steinbrüchel, Daniel

2014-03-01

The number of lung transplantations is limited by a general lack of donor organs. Ex vivo lung perfusion (EVLP) is a novel method to optimise and evaluate marginal donor lungs prior to transplantation. We describe our experiences with EVLP in Denmark during the first year after its introduction. The study was conducted by prospective registration of donor offers and lung transplantations in Denmark from 1 May 2012 to 30 April 2013. Donor lungs without any contraindications were transplanted in the traditional manner. Taken for EVLP were donor lungs that were otherwise considered transplantable, but failed to meet the usual criteria due to possible contusions or because they were from donors with sepsis or unable to pass the oxygenation test. In the study period, seven of 33 Danish lung transplantations were made possible due to EVLP. One patient died of non-EVLP-related causes, but all other recipients were alive with normal graft function at the end of our registration period. All lungs showed an improved PaO2/FiO2 ratio from a median 23.1 kPa (8.8-38.9) within the donor to 58.8 kPa (34.9-76.5) (FiO2 = 1.0) after EVLP, which corresponds to a 155% improved oxygenation. The median time to extubation, time in intensive care unit and the admission period were 1, 7 and 39 days, respectively. In the first year after the introduction of EVLP in Denmark, seven pairs of donor lungs that previously would have been rejected have been transplanted as a result of their improved function. EVLP seems to be a safe way to increase the use of marginal donor lungs. no funding was granted for the present paper. not relevant.

Changes in Functional Lung Regions During the Course of Radiation Therapy and Their Potential Impact on Lung Dosimetry for Non-Small Cell Lung Cancer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Meng, Xue; Department of Radiation Oncology, Shandong Cancer Hospital, Shandong University, Jinan; Frey, Kirk

2014-05-01

Purpose: To study changes in functional activity on ventilation (V)/perfusion (Q) single-photon emission computed tomography (SPECT) during radiation therapy (RT) and explore the impact of such changes on lung dosimetry in patients with non-small cell lung cancer (NSCLC). Methods and Materials: Fifteen NSCLC patients with centrally located tumors were enrolled. All patients were treated with definitive RT dose of ≥60 Gy. V/Q SPECT-CT scans were performed prior to and after delivery of 45 Gy of fractionated RT. SPECT images were used to define temporarily dysfunctional regions of lung caused by tumor or other potentially reversible conditions as B3. The functional lung (FL)more » was defined on SPECT by 2 separate approaches: FL1, a threshold of 30% of the maximum uptake of the patient's lung; and FL2, FL1 plus B3 region. The impact of changes in FL between initiation of RT and delivery of 45 Gy on lung dosimetry were analyzed. Results: Fourteen patients (93%) had larger FL2 volumes than FL1 pre-RT (P<.001). Dysfunctional lung became functional in 11 patients (73%) on V SPECT and in 10 patients (67%) on Q SPECT. The dosimetric parameters generated from CT-based anatomical lung had significantly lower values in FL1 than FL2, with a median reduction in the volume of lung receiving a dose of at least 20 Gy (V{sub 20}) of 3%, 5.6%, and mean lung dose of 0.95 and 1.55 on V and Q SPECT respectively. Conclusions: Regional ventilation and perfusion function improve significantly during RT in centrally located NSCLC. Lung dosimetry values vary notably between different definitions of functional lung.« less

Lung cancer-A global perspective.

PubMed

McIntyre, Amanda; Ganti, Apar Kishor

2017-04-01

Lung cancer is the leading cause of cancer deaths worldwide. While tobacco exposure is responsible for the majority of lung cancers, the incidence of lung cancer in never smokers, especially Asian women, is increasing. There is a global variation in lung cancer biology with EGFR mutations being more common in Asian patients, while Kras mutation is more common in Caucasians. This review will focus on the global variations in lung cancer and its treatment. © 2017 Wiley Periodicals, Inc.

PREOPERATIVE PREDICTION OF LUNG FUNCTION IN PNEUMONECTOMY BY SPIROMETRY AND LUNG PERFUSION SCINTIGRAPHY

PubMed Central

Cukic, Vesna

2012-01-01

Introduction: Nowadays an increasing number of lung resections are being done because of the rising prevalence of lung cancer that occurs mainly in patients with limited lung function, what is caused by common etiologic factor - smoking cigarettes. Loss of lung tissue in such patients can worsen much the postoperative pulmonary function. So it is necessary to asses the postoperative pulmonary function especially after maximal resection, i.e. pneumonectomy. Objective: To check over the accuracy of preoperative prognosis of postoperative lung function after pneumonectomy using spirometry and lung perfusion scinigraphy. Material and methods: The study was done on 17 patients operated at the Clinic for thoracic surgery, who were treated previously at the Clinic for Pulmonary Diseases “Podhrastovi” in the period from 01. 12. 2008. to 01. 06. 2011. Postoperative pulmonary function expressed as ppoFEV1 (predicted postoperative forced expiratory volume in one second) was prognosticated preoperatively using spirometry, i.e.. simple calculation according to the number of the pulmonary segments to be removed and perfusion lung scintigraphy. Results: There is no significant deviation of postoperative achieved values of FEV1 from predicted ones obtained by both methods, and there is no significant differences between predicted values (ppoFEV1) obtained by spirometry and perfusion scintigraphy. Conclusion: It is necessary to asses the postoperative pulmonary function before lung resection to avoid postoperative respiratory failure and other cardiopulmonary complications. It is absolutely necessary for pneumonectomy, i.e.. maximal pulmonary resection. It can be done with great possibility using spirometry or perfusion lung scintigraphy. PMID:23378687

The metastatic microenvironment: lung-derived factors control the viability of neuroblastoma lung metastasis.

PubMed

Maman, Shelly; Edry-Botzer, Liat; Sagi-Assif, Orit; Meshel, Tsipi; Yuan, Weirong; Lu, Wuyuan; Witz, Isaac P

2013-11-15

Recent data suggest that the mechanisms determining whether a tumor cell reaching a secondary organ will enter a dormant state, progress toward metastasis, or go through apoptosis are regulated by the microenvironment of the distant organ. In neuroblastoma, 60-70% of children with high-risk disease will ultimately experience relapse due to the presence of micrometastases. The main goal of this study is to evaluate the role of the lung microenvironment in determining the fate of neuroblastoma lung metastases and micrometastases. Utilizing an orthotopic mouse model for human neuroblastoma metastasis, we were able to generate two neuroblastoma cell populations-lung micrometastatic (MicroNB) cells and lung macrometastatic (MacroNB) cells. These two types of cells share the same genetic background, invade the same distant organ, but differ in their ability to create metastasis in the lungs. We hypothesize that factors present in the lung microenvironment inhibit the propagation of MicroNB cells preventing them from forming overt lung metastasis. This study indeed shows that lung-derived factors significantly reduce the viability of MicroNB cells by up regulating the expression of pro-apoptotic genes, inducing cell cycle arrest and decreasing ERK and FAK phosphorylation. Lung-derived factors affected various additional progression-linked cellular characteristics of neuroblastoma cells, such as the expression of stem-cell markers, morphology, and migratory capacity. An insight into the microenvironmental effects governing neuroblastoma recurrence and progression would be of pivotal importance as they could have a therapeutic potential for the treatment of neuroblastoma residual disease. Copyright © 2013 UICC.

Dutch Lung Surgery Audit: A National Audit Comprising Lung and Thoracic Surgery Patients.

PubMed

Berge, Martijn Ten; Beck, Naomi; Heineman, David Jonathan; Damhuis, Ronald; Steup, Willem Hans; van Huijstee, Pieter Jan; Eerenberg, Jan Peter; Veen, Eelco; Maat, Alexander; Versteegh, Michel; van Brakel, Thomas; Schreurs, Wilhemina Hendrika; Wouters, Michel Wilhelmus

2018-04-21

The nationwide Dutch Lung Surgery Audit (DLSA) started in 2012 to monitor and evaluate the quality of lung surgery in the Netherlands as an improvement tool. This outline describes the establishment, structure and organization of the audit by the Dutch Society of Lung Surgeons (NVvL) and the Dutch Society of Cardiothoracic Surgeons (NVT), in collaboration with the Dutch Institute for Clinical Auditing (DICA). In addition, first four-year results are presented. The NVvL and NVT initiated a web-based registration including weekly updated online feedback for participating hospitals. Data verification by external data managers is performed on regular basis. The audit is incorporated in national quality improvement programs and participation in the DLSA is mandatory by health insurance organizations and the National Healthcare Inspectorate. Between 1 January 2012 and 31 December 2015, all hospitals performing lung surgery participated and a total of 19,557 patients were registered from which almost half comprised lung cancer patients. Nationwide the guideline adherence increased over the years and 96.5% of lung cancer patients were discussed in preoperative multidisciplinary teams. Overall postoperative complications and mortality after non-small cell lung cancer surgery were 15.5% and 2.0%, respectively. The audit provides reliable benchmarked information for caregivers and hospital management with potential to start local, regional or national improvement initiatives. Currently, the audit is further completed with data from non-surgical lung cancer patients including treatment data from pulmonary oncologists and radiation oncologists. This will ultimately provide a comprehensive overview of lung cancer treatment in The Netherlands. Copyright © 2018. Published by Elsevier Inc.

Effect of Normal Lung Definition on Lung Dosimetry and Lung Toxicity Prediction in Radiation Therapy Treatment Planning

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Weili; Department of Radiation Oncology, the Fourth Affiliated Hospital, China Medical University, Shenyang; Xu, Yaping

2013-08-01

Purpose: This study aimed to compare lung dose–volume histogram (DVH) parameters such as mean lung dose (MLD) and the lung volume receiving ≥20 Gy (V20) of commonly used definitions of normal lung in terms of tumor/target subtraction and to determine to what extent they differ in predicting radiation pneumonitis (RP). Methods and Materials: One hundred lung cancer patients treated with definitive radiation therapy were assessed. The gross tumor volume (GTV) and clinical planning target volume (PTV{sub c}) were defined by the treating physician and dosimetrist. For this study, the clinical target volume (CTV) was defined as GTV with 8-mm uniformmore » expansion, and the PTV was defined as CTV with an 8-mm uniform expansion. Lung DVHs were generated with exclusion of targets: (1) GTV (DVH{sub G}); (2) CTV (DVH{sub C}); (3) PTV (DVH{sub P}); and (4) PTV{sub c} (DVH{sub Pc}). The lung DVHs, V20s, and MLDs from each of the 4 methods were compared, as was their significance in predicting radiation pneumonitis of grade 2 or greater (RP2). Results: There are significant differences in dosimetric parameters among the various definition methods (all Ps<.05). The mean and maximum differences in V20 are 4.4% and 12.6% (95% confidence interval 3.6%-5.1%), respectively. The mean and maximum differences in MLD are 3.3 Gy and 7.5 Gy (95% confidence interval, 1.7-4.8 Gy), respectively. MLDs of all methods are highly correlated with each other and significantly correlated with clinical RP2, although V20s are not. For RP2 prediction, on the receiver operating characteristic curve, MLD from DVH{sub G} (MLD{sub G}) has a greater area under curve of than MLD from DVH{sub C} (MLD{sub C}) or DVH{sub P} (MLD{sub P}). Limiting RP2 to 30%, the threshold is 22.4, 20.6, and 18.8 Gy, for MLD{sub G}, MLD{sub C}, and MLD{sub P}, respectively. Conclusions: The differences in MLD and V20 from various lung definitions are significant. MLD from the GTV exclusion method may be more accurate in

[Lung abscess which needed to be distinguished from lung cancer; report of a case].

PubMed

Kamiya, Kazunori; Yoshizu, Akira; Misumi, Yuki; Hida, Naoya; Okamoto, Hiroaki; Yoshida, Sachiko

2011-12-01

Differential diagnosis of lung abscess from lung cancer is sometimes difficult. In February 2009, a 57-year-old man consulted our hospital complaining of bloody sputum. Chest computed tomography (CT) demonstrated a 2.5 cm nodule with pleural indentation, spicula and vascular involvement in the right S(3). Bronchofiberscope could not establish a definitive diagnosis. Blood test showed no abnormality. Three months later, progression of the nodule to the adjacent middle lobe was demonstrated by follow-up CT, and F-18 fluorodeoxyglucose positron emission tomography (FDG-PET) showed isotope accumulation in the nodule and hilar lymph node. A diagnosis of lung cancer was suspected and surgery was performed. The diagnosis of possible lung cancer was made by needle biopsy, and the patient underwent right upper lobectomy and partial resection of middle lobe with standard nodal dissection. The final pathological diagnosis was lung abscess. Lung abscess must be kept in mind as a possible differential diagnosis when abnormal shadow suspected of lung cancer is observed.

Lung PET scan

MedlinePlus

... PET - chest; PET - lung; PET - tumor imaging; PET/CT - lung; Solitary pulmonary nodule - PET ... minutes. PET scans are performed along with a CT scan. This is because the combined information from ...

Effect of shape and size of lung and chest wall on stresses in the lung

NASA Technical Reports Server (NTRS)

Vawter, D. L.; Matthews, F. L.; West, J. B.

1975-01-01

To understand better the effect of shape and size of lung and chest wall on the distribution of stresses, strains, and surface pressures, we analyzed a theoretical model using the technique of finite elements. First we investigated the effects of changing the chest wall shape during expansion, and second we studied lungs of a variety of inherent shapes and sizes. We found that, in general, the distributions of alveolar size, mechanical stresses, and surface pressures in the lungs were dominated by the weight of the lung and that changing the shape of the lung or chest wall had relatively little effect. Only at high states of expansion where the lung was very stiff did changing the shape of the chest wall cause substantial changes. Altering the inherent shape of the lung generally had little effect but the topographical differences in stresses and surface pressures were approximately proportional to lung height. The results are generally consistent with those found in the dog by Hoppin et al (1969).

Postoperative complications do not influence the pattern of early lung function recovery after lung resection for lung cancer in patients at risk

PubMed Central

2014-01-01

Background The pattern and factors influencing the lung function recovery in the first postoperative days are still not fully elucidated, especially in patients at increased risk. Methods Prospective study on 60 patients at increased risk, who underwent a lung resection for primary lung cancer. Inclusion criteria: complete resection and one or more known risk factors in form of COPD, cardiovascular disorders, advanced age or other comorbidities. Previous myocardial infarction, myocardial revascularization or stenting, cardiac rhythm disorders, arterial hypertension and myocardiopathy determined the increased cardiac risk. The severity of COPD was graded according to GOLD criteria. The trend of the postoperative lung function recovery was assessed by performing spirometry with a portable spirometer. Results Cardiac comorbidity existed in 55%, mild and moderate COPD in 20% and 35% of patients respectively. Measured values of FVC% and FEV1% on postoperative days one, three and seven, showed continuous improvement, with significant difference between the days of measurement, especially between days three and seven. There was no difference in the trend of the lung function recovery between patients with and without postoperative complications. Whilst pO2 was decreasing during the first three days in a roughly parallel fashion in patients with respiratory, surgical complications and in patients without complications, a slight hypercapnia registered on the first postoperative day was gradually abolished in all groups except in patients with cardiac complications. Conclusion Extent of the lung resection and postoperative complications do not significantly influence the trend of the lung function recovery after lung resection for lung cancer. PMID:24884793

History of Lung and Heart-Lung Transplantation, With Special Emphasis on German-Speaking Countries.

PubMed

Margreiter, R

2016-10-01

The first experimental lung transplants were performed in 1947 by the Russian surgeon V.P. Demikhov. Thereafter, various aspects associated with lung transplantation were studied by groups from Italy, France, and mainly the United States. The first clinical lung transplant took place in Jackson, Mississippi, in 1963 and was performed by D. Hardy. Until 1983, a total of 45 lung transplants were carried out at various centers, but only one patient transplanted in Ghent by F. Derom in 1968 survived for 10 months, whereas all other patients survived only hours to a few days. In 1983 at Toronto General Hospital, a single-lung transplant was performed that survived almost 7 years. From the same institution, the first long-term survivor after double-lung transplantation was reported in 1986. The first lobar transplant from a live donor was performed by V.A. Starnes at Stanford in 1990. The first heart-lung transplantation was performed in Houston by D.A. Cooley in 1968. Even though the girl who received this transplant survived only for 14 hours, this case showed that this kind of procedure can work. The first long-term survival was achieved by B. Reitz in 1981 in Stanford. In the German-speaking countries, successful lung and lung-heart transplants were reported between 1984 and 1993 and are described in detail. Copyright © 2016 Elsevier Inc. All rights reserved.

A neutrophil elastase inhibitor improves lung function during ex vivo lung perfusion.

PubMed

Harada, Masaaki; Oto, Takahiro; Otani, Shinji; Miyoshi, Kentaroh; Okada, Masanori; Iga, Norichika; Nishikawa, Hitoshi; Sugimoto, Seiichiro; Yamane, Masaomi; Miyoshi, Shinichiro

2015-12-01

Ex vivo lung perfusion (EVLP) has been used not only for graft evaluation but also for graft reconditioning prior to lung transplantation. Inflammatory cells such as neutrophils may cause additional graft injury during EVLP. Neutrophil elastase inhibitors protect lungs against neutrophil-induced lung injury, such as acute respiratory distress syndrome. This study aimed to investigate the effect of a neutrophil elastase inhibitor during EVLP. EVLP was performed for 4 h in bilateral pig lungs that had previously experienced warm ischemia for 2 h with or without a neutrophil elastase inhibitor (treated and control groups, respectively; n = 6). Following EVLP, the left lung was transplanted into a recipient pig, and this was followed by observation for 4 h. Pulmonary functions were observed both during EVLP and during the early post-transplant stage. During EVLP, decreases in neutrophil elastase levels (P < 0.001), the wet-dry weight ratio (P < 0.05), and pulmonary vascular resistance (P < 0.01) and increases in the PaO2/FiO2 ratio (P < 0.01) and pulmonary compliance (P < 0.05) were observed in the treated group. After transplantation, decreased pulmonary vascular resistance (P < 0.05) was observed in the treated group. A neutrophil elastase inhibitor attenuated the inflammatory response during EVLP and may decrease the incidence of lung reperfusion injury after transplantation.

Lung Dosimetry for Radioiodine Treatment Planning in the Case of Diffuse Lung Metastases

PubMed Central

Song, Hong; He, Bin; Prideaux, Andrew; Du, Yong; Frey, Eric; Kasecamp, Wayne; Ladenson, Paul W.; Wahl, Richard L.; Sgouros, George

2010-01-01

The lungs are the most frequent sites of distant metastasis in differentiated thyroid carcinoma. Radioiodine treatment planning for these patients is usually performed following the Benua– Leeper method, which constrains the administered activity to 2.96 GBq (80 mCi) whole-body retention at 48 h after administration to prevent lung toxicity in the presence of iodine-avid lung metastases. This limit was derived from clinical experience, and a dosimetric analysis of lung and tumor absorbed dose would be useful to understand the implications of this limit on toxicity and tumor control. Because of highly nonuniform lung density and composition as well as the nonuniform activity distribution when the lungs contain tumor nodules, Monte Carlo dosimetry is required to estimate tumor and normal lung absorbed dose. Reassessment of this toxicity limit is also appropriate in light of the contemporary use of recombinant thyrotropin (thyroid-stimulating hormone) (rTSH) to prepare patients for radioiodine therapy. In this work we demonstrated the use of MCNP, a Monte Carlo electron and photon transport code, in a 3-dimensional (3D) imaging–based absorbed dose calculation for tumor and normal lungs. Methods A pediatric thyroid cancer patient with diffuse lung metastases was administered 37MBq of 131I after preparation with rTSH. SPECT/CT scans were performed over the chest at 27, 74, and 147 h after tracer administration. The time–activity curve for 131I in the lungs was derived from the whole-body planar imaging and compared with that obtained from the quantitative SPECT methods. Reconstructed and coregistered SPECT/CT images were converted into 3D density and activity probability maps suitable for MCNP4b input. Absorbed dose maps were calculated using electron and photon transport in MCNP4b. Administered activity was estimated on the basis of the maximum tolerated dose (MTD) of 27.25 Gy to the normal lungs. Computational efficiency of the MCNP4b code was studied with a

Diesel exhaust particle promotes tumor lung metastasis via the induction of BLT1-mediated neutrophilic lung inflammation.

PubMed

Li, Wenjing; Liu, Ting; Xiong, Yingluo; Lv, Jiaoyan; Cui, Xinyi; He, Rui

2018-06-05

BLT1, the primary functional receptor of Leukotriene B4 (LTB4), is involved in tissue inflammation by mediating leukocyte recruitment, and recently LTB4-dependent inflammation was reported to promote lung tumor growth. Exposure to diesel exhaust particle (DEP), the major component of particulate matter 2.5 (PM 2.5 ), can elicit lung inflammation, which may increase the risk of lung cancer. However, it remains unknown about the critical factors mediating DEP-induced lung inflammation and the subsequent effect on tumor metastasis. In this study, we found that DEP exposure led to acute lung inflammation, characterized by abundant infiltration of neutrophils and elevated lung levels in LTB4, as well as several pro-inflammatory cytokines and chemokines, including IL-1β, IL-6, TNF-α, CXCL1/2. Furthermore, DEP exposure promoted lung metastasis of 3LL and 4T1 cells. BLT1 blockade by its specific antagonist U75302 significantly inhibited neutrophilic lung inflammation following DEP exposure. Importantly, BLT1 blockade before the onset of inflammation significantly reduced DEP-enhanced lung metastasis, which was associated with greatly decreased infiltrating neutrophils in lungs. Interestingly, BLT1 blockade after the occurrence of lung metastases had no effect on the magnitude of lung metastasis, suggesting that inhibition of BLT1-mediated lung inflammation was insufficient to suppress established metastatic tumor. Administration of BLT2 inhibitor LY255283 fails to inhibit DEP-induced lung inflammation and tumor metastasis. Collectively, our results demonstrate that DEP exposure causes BLT1-mediated lung neutrophilic inflammation, which is critical for tumor lung metastasis, and suggest that interruption of the LTB4-BLT1 axis could be useful for preventing PM 2.5 -induced inflammation and subsequent susceptible to lung metastasis. Copyright © 2018 Elsevier Ltd. All rights reserved.

Lung Parenchymal Mechanics

PubMed Central

Suki, Béla; Stamenovic, Dimitrije; Hubmayr, Rolf

2014-01-01

The lung parenchyma comprises a large number of thin-walled alveoli, forming an enormous surface area, which serves to maintain proper gas exchange. The alveoli are held open by the transpulmonary pressure, or prestress, which is balanced by tissues forces and alveolar surface film forces. Gas exchange efficiency is thus inextricably linked to three fundamental features of the lung: parenchymal architecture, prestress, and the mechanical properties of the parenchyma. The prestress is a key determinant of lung deformability that influences many phenomena including local ventilation, regional blood flow, tissue stiffness, smooth muscle contractility, and alveolar stability. The main pathway for stress transmission is through the extracellular matrix. Thus, the mechanical properties of the matrix play a key role both in lung function and biology. These mechanical properties in turn are determined by the constituents of the tissue, including elastin, collagen, and proteoglycans. In addition, the macroscopic mechanical properties are also influenced by the surface tension and, to some extent, the contractile state of the adherent cells. This article focuses on the biomechanical properties of the main constituents of the parenchyma in the presence of prestress and how these properties define normal function or change in disease. An integrated view of lung mechanics is presented and the utility of parenchymal mechanics at the bedside as well as its possible future role in lung physiology and medicine are discussed. PMID:23733644

Association between absolute volumes of lung spared from low-dose irradiation and radiation-induced lung injury after intensity-modulated radiotherapy in lung cancer: a retrospective analysis.

PubMed

Chen, Jinmei; Hong, Jinsheng; Zou, Xi; Lv, Wenlong; Guo, Feibao; Hong, Hualan; Zhang, Weijian

2015-11-01

The aim of this study was to investigate the association between absolute volumes of lung spared from low-dose irradiation and radiation-induced lung injury (RILI) after intensity-modulated radiotherapy (IMRT) for lung cancer. The normal lung relative volumes receiving greater than 5, 10, 20 and 30 Gy (V5-30) mean lung dose (MLD), and absolute volumes spared from greater than 5, 10, 20 and 30 Gy (AVS5-30) for the bilateral and ipsilateral lungs of 83 patients were recorded. Any association of clinical factors and dose-volume parameters with Grade ≥2 RILI was analyzed. The median follow-up was 12.3 months; 18 (21.7%) cases of Grade 2 RILI, seven (8.4%) of Grade 3 and two (2.4%) of Grade 4 were observed. Univariate analysis revealed the located lobe of the primary tumor. V5, V10, V20, MLD of the ipsilateral lung, V5, V10, V20, V30 and MLD of the bilateral lung, and AVS5 and AVS10 of the ipsilateral lung were associated with Grade ≥2 RILI (P < 0.05). Multivariate analysis indicated AVS5 of the ipsilateral lung was prognostic for Grade ≥2 RILI (P = 0.010, OR = 0.272, 95% CI: 0.102-0.729). Receiver operating characteristic curves indicated Grade ≥2 RILI could be predicted using AVS5 of the ipsilateral lung (area under curve, 0.668; cutoff value, 564.9 cm(3); sensitivity, 60.7%; specificity, 70.4%). The incidence of Grade ≥2 RILI was significantly lower with AVS5 of the ipsilateral lung ≥564.9 cm(3) than with AVS5 < 564.9 cm(3) (P = 0.008). Low-dose irradiation relative volumes and MLD of the bilateral or ipsilateral lung were associated with Grade ≥2 RILI, and AVS5 of the ipsilateral lung was prognostic for Grade ≥2 RILI for lung cancer after IMRT. © The Author 2015. Published by Oxford University Press on behalf of The Japan Radiation Research Society and Japanese Society for Radiation Oncology.

Lung gallium scan

MedlinePlus

... the lungs. This is most often due to sarcoidosis or a certain type of pneumonia. Normal Results ... it may mean any of the following problems: Sarcoidosis (disease in which inflammation occurs in the lungs ...

Lung Cancer: Glossary

MedlinePlus

... effects of radiation therapy Randomized Clinical Trial: Trial design in which participants are assigned by chance to ... effect caused by treatment. Small Cell Lung Cancer: One of the two main categories of lung cancer; ...

HOX Genes in Human Lung

PubMed Central

Golpon, Heiko A.; Geraci, Mark W.; Moore, Mark D.; Miller, Heidi L.; Miller, Gary J.; Tuder, Rubin M.; Voelkel, Norbert F.

2001-01-01

HOX genes belong to the large family of homeodomain genes that function as transcription factors. Animal studies indicate that they play an essential role in lung development. We investigated the expression pattern of HOX genes in human lung tissue by using microarray and degenerate reverse transcriptase-polymerase chain reaction survey techniques. HOX genes predominantly from the 3′ end of clusters A and B were expressed in normal human adult lung and among them HOXA5 was the most abundant, followed by HOXB2 and HOXB6. In fetal (12 weeks old) and diseased lung specimens (emphysema, primary pulmonary hypertension) additional HOX genes from clusters C and D were expressed. Using in situ hybridization, transcripts for HOXA5 were predominantly found in alveolar septal and epithelial cells, both in normal and diseased lungs. A 2.5-fold increase in HOXA5 mRNA expression was demonstrated by quantitative reverse transcriptase-polymerase chain reaction in primary pulmonary hypertension lung specimens when compared to normal lung tissue. In conclusion, we demonstrate that HOX genes are selectively expressed in the human lung. Differences in the pattern of HOX gene expression exist among fetal, adult, and diseased lung specimens. The altered pattern of HOX gene expression may contribute to the development of pulmonary diseases. PMID:11238043

[Epidemiology of lung tumors].

PubMed

Ott, S; Geiser, T

2012-07-01

Approximately one out of 500 chest radiographs shows the incidental finding of a solitary pulmonary nodule and almost one half of these pulmonary lesions are caused by a tumor. Unfortunately, only 2% to 5% of all lung tumors are of benign origin, e. g. lipoma, fibroma, hamartoma, and chondroma, and the majority are malignant neoplasms, most commonly primary lung cancer followed by metastases of extrapulmonary primary carcinomas. Thus, a careful diagnostic work up of solitary pulmonary nodules, including histological diagnosis, is mandatory for an adequate management and treatment of patients with pulmonary lesions. Despite all recent improvements of treatment modalities, lung cancer continues to be a major cause of morbidity and mortality among malignant diseases worldwide. The prognosis of affected patients is still very poor and a 5-years survival rate of only 14% makes lung cancer the number one cause of death due to cancer in Switzerland. Active and passive tobacco smoking are by far the best known risk factor for the development of lung cancer, but there are severe other probably less known factors that may increase the individual risk for malignant neoplasms of the lung. These risk factors include e. g. exposure to natural ionic radiation, consisting of terrestrial radiation and indoor radiation caused by radon gas, exposure to respirable dust and Diesel engine emissions, asbestos, and polycyclic aromatic hydrocarbons. In the majority of cases, the latency between exposure and development of cancer is years to decades and the person concerned was occupationally exposed. Therefore, a detailed evaluation of a patient's medical and occupational history is needed. Due to its poor prognosis, prevention and early diagnosis of lung cancer is crucial to improve our patients' outcome. Good knowledge of epidemiology and aetiology of pulmonary tumors is the key to preventive measures and identification of individuals at increased risk for lung cancer. An overview will

Prepracticum Counseling Students' Perceived Preparedness for Suicide Response

ERIC Educational Resources Information Center

Binkley, Erin E.; Leibert, Todd W.

2015-01-01

The researchers examined how suicide-response training received before practicum related to degrees of anxiety and confidence for practicum students regarding the treatment of suicidal clients. Results of 113 surveyed practicum students are discussed, along with implications and suggestions for future research.

Donor Lung Procurement by Surgical Fellow with an Expectation of High Rate of Lung Utilisation.

PubMed

Smail, Hassiba; Saxena, Pankaj; Wallinder, Andreas; Lin, Enjarn; Snell, Gregory I; Hobson, Jamie; Zimmet, Adam D; Marasco, Silvana F; McGiffin, David C

2017-12-22

There is an ever increasing demand for donor lungs in patients waiting for transplantation. Lungs of many potential donors will be rejected if the standard criteria for donor assessment are followed. We have expanded our donor lung pool by accepting marginal donors and establishing a donation after circulatory death program. We have achieved comparable results using marginal donors and accepting donor lungs following donation after circulatory death. We present our assessment and technical guidelines on lung procurement taking into consideration an increasingly complex cohort of lung donors. These guidelines form the basis of the lung procurement training program involving surgical Fellows at the Alfred Hospital in Melbourne, Australia. Copyright © 2017 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ). Published by Elsevier B.V. All rights reserved.

The Lung Microbiome, Immunity and the Pathogenesis of Chronic Lung Disease1

PubMed Central

O’Dwyer, David N.; Dickson, Robert P.; Moore, Bethany B.

2016-01-01

The development of culture-independent techniques for microbiological analysis has uncovered the previously unappreciated complexity of the bacterial microbiome at various anatomic sites. The microbiome of the lung has relatively less bacterial biomass when compared to the lower gastrointestinal tract yet displays considerable diversity. The composition of the lung microbiome is determined by elimination, immigration and relative growth within its communities. Chronic lung disease alters these factors. Many forms of chronic lung disease demonstrate exacerbations that drive disease progression and are poorly understood. Mounting evidence supports ways in which microbiota dysbiosis can influence host defense and immunity, and in turn may contribute to disease exacerbations. Thus, the key to understanding the pathogenesis of chronic lung disease may reside in deciphering the complex interactions between the host, pathogen and resident microbiota during stable disease and exacerbations. In this brief review we discuss new insights into these labyrinthine relationships. PMID:27260767

Mesenchymal Stem Cells Adopt Lung Cell Phenotype in Normal and Radiation-induced Lung Injury Conditions.

PubMed

Maria, Ola M; Maria, Ahmed M; Ybarra, Norma; Jeyaseelan, Krishinima; Lee, Sangkyu; Perez, Jessica; Shalaby, Mostafa Y; Lehnert, Shirley; Faria, Sergio; Serban, Monica; Seuntjens, Jan; El Naqa, Issam

2016-04-01

Lung tissue exposure to ionizing irradiation can invariably occur during the treatment of a variety of cancers leading to increased risk of radiation-induced lung disease (RILD). Mesenchymal stem cells (MSCs) possess the potential to differentiate into epithelial cells. However, cell culture methods of primary type II pneumocytes are slow and cannot provide a sufficient number of cells to regenerate damaged lungs. Moreover, effects of ablative radiation doses on the ability of MSCs to differentiate in vitro into lung cells have not been investigated yet. Therefore, an in vitro coculture system was used, where MSCs were physically separated from dissociated lung tissue obtained from either healthy or high ablative doses of 16 or 20 Gy whole thorax irradiated rats. Around 10±5% and 20±3% of cocultured MSCs demonstrated a change into lung-specific Clara and type II pneumocyte cells when MSCs were cocultured with healthy lung tissue. Interestingly, in cocultures with irradiated lung biopsies, the percentage of MSCs changed into Clara and type II pneumocytes cells increased to 40±7% and 50±6% at 16 Gy irradiation dose and 30±5% and 40±8% at 20 Gy irradiation dose, respectively. These data suggest that MSCs to lung cell differentiation is possible without cell fusion. In addition, 16 and 20 Gy whole thorax irradiation doses that can cause varying levels of RILD, induced different percentages of MSCs to adopt lung cell phenotype compared with healthy lung tissue, providing encouraging outlook for RILD therapeutic intervention for ablative radiotherapy prescriptions.

Effect of the lung allocation score on lung transplantation in the United States.

PubMed

Egan, Thomas M; Edwards, Leah B

2016-04-01

On May 4, 2005, the system for allocation of deceased donor lungs for transplant in the United States changed from allocation based on waiting time to allocation based on the lung allocation score (LAS). We sought to determine the effect of the LAS on lung transplantation in the United States. Organ Procurement and Transplantation Network data on listed and transplanted patients were analyzed for 5 calendar years before implementation of the LAS (2000-2004), and compared with data from 6 calendar years after implementation (2006-2011). Counts were compared between eras using the Wilcoxon rank sum test. The rates of transplant increase within each era were compared using an F-test. Survival rates computed using the Kaplan-Meier method were compared using the log-rank test. After introduction of the LAS, waitlist deaths decreased significantly, from 500/year to 300/year; the number of lung transplants increased, with double the annual increase in rate of lung transplants, despite no increase in donors; the distribution of recipient diagnoses changed dramatically, with significantly more patients with fibrotic lung disease receiving transplants; age of recipients increased significantly; and 1-year survival had a small but significant increase. Allocating lungs for transplant based on urgency and benefit instead of waiting time was associated with fewer waitlist deaths, more transplants performed, and a change in distribution of recipient diagnoses to patients more likely to die on the waiting list. Copyright © 2016 International Society for Heart and Lung Transplantation. All rights reserved.

Stages of Small Cell Lung Cancer

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... Lung Cancer Prevention Lung Cancer Screening Research Small Cell Lung Cancer Treatment (PDQ®)–Patient Version General Information About Small Cell Lung Cancer Go to Health Professional Version Key ...

Comparison between semantic features and lung-RADS in predicting malignancy of screening lung nodule

PubMed Central

Li, Qian; Balagurunathan, Yoganand; Liu, Ying; Qi, Jin; Schabath, Matthew B.; Ye, Zhaoxiang; Gillies, Robert

2017-01-01

Rationale Lung-RADS is proposed for the Low-dose computed tomography (LDCT) interpretation in lung cancer screening, but its performance needs to be further evaluated. Objectives To compare the value of radiological semantic features and lung-RADS in predicting nodule malignancy risk at different screening rounds, and to investigate whether the predictive power of lung-RADS could be improved by incorporating semantic features. Methods A training cohort of 199 patients (139 benign and 60 cancerous nodules diagnosed at the third screening round), and a testing cohort of 80 patients (40 benign and 40 malignant nodules) were obtained from the National Lung Screening Trial dataset. A multivariate linear predictor model was built based on the 24 systematically scored semantic features, and the performances were compared to lung-RADS (scale 3 or above called positive). Measurements and Main Results Among the semantic features, contour and border definition were the top individual predictors. The average area under the receiver-operating characteristic curve (AUC) of border definition at baseline (T0) was 0.724. The average AUC of contour at first (T1) and second follow-up (T2) were 0.843 and 0.878, respectively. Other significant features included size, location, vessel attachment, solidity, focal emphysema and focal fibrosis. In comparison, the average AUC of lung-RADS at T0, T1 and T2 were 0.600, 0.760 and 0.867, respectively, and could be improved to 0.743, 0.887 and 0.968 by adding semantic features. Conclusion The semantic features performed similar to lung-RADS at follow-ups, outperformed lung-RADS at baseline, and could improve the performance of lung-RADS for all screening rounds. PMID:29137847

Isolated lung transplantation for end-stage lung disease: a viable therapy.

PubMed

Egan, T M; Westerman, J H; Lambert, C J; Detterbeck, F C; Thompson, J T; Mill, M R; Keagy, B A; Paradowski, L J; Wilcox, B R

1992-04-01

Since January 1990, we have performed 29 isolated lung transplantations in 28 patients with end-stage lung disease (12 single, 16 bilateral). Recipient diagnoses were: cystic fibrosis (11), chronic obstructive pulmonary disease (6), pulmonary fibrosis (6), eosinophilic granulomatosis (1), postinfectious lung disease (1), adult respiratory distress syndrome (1), and primary pulmonary hypertension (2). There have been four deaths, two in patients with pulmonary fibrosis and two in patients with primary pulmonary hypertension. Four patients have undergone transplantation while on ventilatory support for respiratory failure (2 with cystic fibrosis, 1 having redo lung transplantation with cystic fibrosis, and 1 with adult respiratory distress syndrome); all of these have survived. Six patients required cardiopulmonary bypass, which was associated with increased transfusion requirement. All patients 2 months after discharge have returned to an active life-style, except for 2 patients who currently await retransplantation. Preoperative pulmonary rehabilitation has resulted in significant improvement in exercise performance in all patients. Immunosuppression consists of cyclosporine, azathioprine, and antilymphoblast globulin (University of Minnesota), withholding systemic steroids in the early postoperative period. We have employed bronchial omentopexy in all but four transplants; there has been one partial bronchial dehiscence, two instances of bronchomalacia requiring internal stenting, and one airway stenosis. Cytomegalovirus disease has been seen frequently (15 cases), but has responded well to treatment with ganciclovir. Other complication shave included one drug-related prolonged postoperative ventilation, thrombosis of a left lung after bilateral lung transplantation requiring retransplantation, five episodes of unilateral phrenic nerve palsy after bilateral lung transplantation (4 resolved), and the requirement of massive transfusion (greater than 10 units) in 5

Promotion of Lung Health: NHLBI Workshop on the Primary Prevention of Chronic Lung Diseases

PubMed Central

Budinger, G. R. Scott; Escobar, Gabriel J.; Hansel, Nadia N.; Hanson, Corrine K.; Huffnagle, Gary B.; Buist, A. Sonia

2014-01-01

Lung-related research primarily focuses on the etiology and management of diseases. In recent years, interest in primary prevention has grown. However, primary prevention also includes “health promotion” (actions in a population that keep an individual healthy). We encourage more research on population-based (public health) strategies that could not only maximize lung health but also mitigate “normal” age-related declines—not only for spirometry but across multiple measures of lung health. In developing a successful strategy, a “life course” approach is important. Unfortunately, we are unable to achieve the full benefit of this approach until we have better measures of lung health and an improved understanding of the normal trajectory, both over an individual’s life span and possibly across generations. We discuss key questions in lung health promotion, with an emphasis on the upper (healthier) end of the distribution of lung functioning and resiliency and briefly summarize the few interventions that have been studied to date. We conclude with suggestions regarding the most promising future research for this important, but largely neglected, area of lung research. PMID:24754821

Lung Cancer and Lung Injury: The Dual Role of Ceramide

PubMed Central

Goldkorn, Tzipora; Chung, Samuel; Filosto, Simone

2015-01-01

Sphingolipids play key roles in cancer, yet our current understanding of sphingolipid function in lung cancer is limited to a few key players. The best characterized of these are sphingosine-1-phoshate and ceramide which are described for their opposing roles in cell fate. However, because sphingolipids as a whole are readily interconverted by a complex enzymatic machinery, no single sphingolipid appears to have exactly one role. Instead, the roles of specific sphingolipids appear to be context specific as demonstrated by findings that ceramide-1-phosphate has both proliferative and apoptotic effects depending on its concentration. Therefore, we present herein several years of research on ceramide, a sphingolipid linked to apoptotic signaling, that is emerging in cancer research for its potential roles in proliferation and cell-to-cell communication via exosomes. Ceramide is a well-studied sphingolipid in both normal and pathological conditions ranging from skin development to lung cancer. Interestingly, several groups have previously reported its increased levels in emphysema patients who are smokers, a patient subpopulation greatly susceptible to lung cancer. However, the molecular mechanisms through which cigarette smoke (CS) and ceramide accumulation lead to lung cancer, non-small cell lung cancer (NSCLC) specifically, are unknown. Interestingly, recent studies clearly establish that two signaling pathways are activated during CS exposure in the lung airway. One centers on the activation of neutral sphingomyelinase2 (nSMase2), an enzyme that hydrolyzes sphingomyelin to ceramide. The other pathway focuses on the oncogenic EGF receptor (EGFR), which becomes aberrantly activated but not degraded, leading to prolonged proliferative signaling. Recent studies show that these two signaling pathways may actually converge and integrate. Specifically, Goldkorn et al. demonstrated that during CS exposure, EGFR is favorably co-localized in ceramide-enriched regions of the

Lung inflation with hydrogen during the cold ischemia phase decreases lung graft injury in rats

PubMed Central

Liu, Rongfang; Fang, Xianhai; Meng, Chao; Xing, Jingchun; Liu, Jinfeng; Yang, Wanchao

2015-01-01

Hydrogen has antioxidant and anti-inflammatory effects on lung ischemia–reperfusion injury when it is inhaled by donor or/and recipient. This study examined the effects of lung inflation with 3% hydrogen during the cold ischemia phase on lung graft function in rats. The donor lung was inflated with 3% hydrogen, 40% oxygen, and 57% nitrogen at 5 mL/kg, and the gas was replaced every 20 min during the cold ischemia phase for 2 h. In the control group, the donor lung was inflated with 40% oxygen and 60% nitrogen at 5 mL/kg. The recipient was euthanized 2 h after orthotropic lung transplantation. The hydrogen concentration in the donor lung during the cold ischemia phase was 1.99–3%. The oxygenation indices in the arterial blood and pulmonary vein blood were improved in the hydrogen group. The inflammation response indices, including lung W/D ratio, the myeloperoxidase activity in the grafts, and the levels of IL-8 and TNF-α in serum, were significantly lower in the hydrogen group (5.2 ± 0.8, 0.76 ± 0.32 U/g, 340 ± 84 pg/mL, and 405 ± 115 pg/mL, respectively) than those in the control group (6.5 ± 0.7, 1.1 ± 0.5 U/g, 443 ± 94 pg/mL, and 657 ± 96 pg/mL, respectively (P < 0.05), and the oxidative stress indices, including the superoxide dismutase activity and the level of malonaldehyde in lung grafts were improved after hydrogen application. Furthermore, the lung injury score determined by histopathology, the cell apoptotic index, and the caspase-3 protein expression in lung grafts were decreased after hydrogen treatment, and the static pressure–volume curve of lung graft was improved by hydrogen inflation. In conclusion, lung inflation with 3% hydrogen during the cold ischemia phase alleviated lung graft injury and improved graft function. PMID:25662956

Hypercapnic acidosis modulates inflammation, lung mechanics, and edema in the isolated perfused lung.

PubMed

De Smet, Hilde R; Bersten, Andrew D; Barr, Heather A; Doyle, Ian R

2007-12-01

Low tidal volume (V(T)) ventilation strategies may be associated with permissive hypercapnia, which has been shown by ex vivo and in vivo studies to have protective effects. We hypothesized that hypercapnic acidosis may be synergistic with low V(T) ventilation; therefore, we studied the effects of hypercapnia and V(T) on unstimulated and lipopolysaccharide-stimulated isolated perfused lungs. Isolated perfused rat lungs were ventilated for 2 hours with low (7 mL/kg) or moderately high (20 mL/kg) V(T) and 5% or 20% CO(2), with lipopolysaccharide or saline added to the perfusate. Hypercapnia resulted in reduced pulmonary edema, lung stiffness, tumor necrosis factor alpha (TNF-alpha) and interleukin 6 (IL-6) in the lavage and perfusate. The moderately high V(T) did not cause lung injury but increased lavage IL-6 and perfusate IL-6 as well as TNF-alpha. Pulmonary edema and respiratory mechanics improved, possibly as a result of a stretch-induced increase in surfactant turnover. Lipopolysaccharide did not induce significant lung injury. We conclude that hypercapnia exerts a protective effect by modulating inflammation, lung mechanics, and edema. The moderately high V(T) used in this study stimulated inflammation but paradoxically improved edema and lung mechanics with an associated increase in surfactant release.

Sirolimus and Auranofin in Treating Patients With Advanced or Recurrent Non-Small Cell Lung Cancer or Small Cell Lung Cancer

ClinicalTrials.gov

2017-08-28

Extensive Stage Small Cell Lung Carcinoma; Lung Adenocarcinoma; Recurrent Non-Small Cell Lung Carcinoma; Recurrent Small Cell Lung Carcinoma; Squamous Cell Lung Carcinoma; Stage IIIA Non-Small Cell Lung Cancer; Stage IIIB Non-Small Cell Lung Cancer; Stage IV Non-Small Cell Lung Cancer

Lung microenvironment promotes the metastasis of human hepatocellular carcinoma cells to the lungs.

PubMed

Jin, Yun; Ai, Junhua; Shi, Jun

2015-01-01

Cancer metastasis is a highly tissue-specific and organ-selective process. It has been shown that the affected tissues and/or organs play a major role in this complex process. The lung is the most common target organ of extrahepatic hepatocellular carcinoma (HCC) metastasis, but the precise molecular mechanism underlying this organ-specific metastasis remains unclear. We hypothesized that lung microenvironment was able to promote the metastasis of HCC cells to the lungs leading to distant metastases. In support of our hypothesis, we provided evidence from targeted metastasis in various types of cancer and contributing factors in the microenvironment of targeted tissues/organs. A better understanding of the steps involved in the interplay between HCC cells and lung microenvironment may offer new perspectives for the medical management of lung metastases of HCC.

Lung deformations and radiation-induced regional lung collapse in patients treated with stereotactic body radiation therapy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Diot, Quentin, E-mail: quentin.diot@ucdenver.edu; Kavanagh, Brian; Vinogradskiy, Yevgeniy

2015-11-15