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1

Aircraft as Research Tools  

NASA Technical Reports Server (NTRS)

Aeronautical research usually begins with computers, wind tunnels, and flight simulators, but eventually the theories must fly. This is when flight research begins, and aircraft are the primary tools of the trade. Flight research involves doing precision maneuvers in either a specially built experimental aircraft or an existing production airplane that has been modified. For example, the AD-1 was a unique airplane made only for flight research, while the NASA F-18 High Alpha Research Vehicle (HARV) was a standard fighter aircraft that was transformed into a one-of-a-kind aircraft as it was fitted with new propulsion systems, flight controls, and scientific equipment. All research aircraft are able to perform scientific experiments because of the onboard instruments that record data about its systems, aerodynamics, and the outside environment. Since the 1970's, NASA flight research has become more comprehensive, with flights involving everything form Space Shuttles to ultralights. NASA now flies not only the fastest airplanes, but some of the slowest. Flying machines continue to evolve with new wing designs, propulsion systems, and flight controls. As always, a look at today's experimental research aircraft is a preview of the future.

1999-01-01

2

Semantic Web Research anno 2006: main streams,  

E-print Network

Semantic Web Research anno 2006: main streams, popular fallacies, current status and future. In this topical1 paper we try to give an analysis and overview of the current state of Semantic Web research. We point to different in- terpretations of the Semantic Web as the reason underlying many contro- versies

van Harmelen, Frank

3

Gulf of Maine Research Institute: Atlantic Herring  

NSDL National Science Digital Library

Created by the Gulf of Maine Research Institute, this website offers several interesting perspectives on a very important fish in the food chain -- the Atlantic Herring (_Clupea harengus_). The website organizes information about the Atlantic Herring into three main categories: Biology; Harvest and Processing; and Research. The site utilizes beautiful photos, illustrations, and maps as it briefly describes herring life cycle, distribution, spawning research, mid-water trawling, processing, and much more. The website also provides a solid collection of herring resources and references.

4

Semantic Web research main streams, popular falacies,  

E-print Network

;10 Which Semantic Web? Version 2: "Enrichment of the current Web" recipe: Annotate, classify, index metaSemantic Web research anno 2006: main streams, popular falacies, current status, future challenges Frank van Harmelen Vrije Universiteit Amsterdam #12;2 This is NOT a Semantic Web evangelization talk (I

van Harmelen, Frank

5

HEI Tools for Researchers  

Cancer.gov

This page provides information about the basic steps for calculating HEI component and total scores and further details for calculating scores at different levels of analysis (i.e., national food supply, food processing, community food environment, and individual food intake). Refer to the Research Uses page for more details about these levels and the types of studies that can be conducted at each.

6

Bioinformatic tools in Arabidopsis research.  

PubMed

Bioinformatic tools are an increasingly important resource for Arabidopsis researchers. With them, it is possible to rapidly query the large data sets covering genomes, transcriptomes, proteomes, epigenomes, and other "omes" that have been generated in the past decade. Often these tools can be used to generate quality hypotheses at the click of a mouse. In this chapter, we cover the use of bioinformatic tools for examining gene expression and coexpression patterns, performing promoter analyses, looking for functional classification enrichment for sets of genes, and investigating protein-protein interactions. We also introduce bioinformatic tools that allow integration of data from several sources for improved hypothesis generation. PMID:24057362

de Lucas, Miguel; Provart, Nicholas J; Brady, Siobhan M

2014-01-01

7

Diigo: An Online Research Tool  

NSDL National Science Digital Library

This Wiki page provides a link to the recording of a webinar by David Hayward. Learn how to use Diigo to keep track of, share, publish, and annotate resources. Diigo is a personal research tool, collaborative research platform, and social information network. Other links to the resources discussed in this webinar are also provided.

2009-10-07

8

Main transformation tools in ANALITIK-93 programming system  

SciTech Connect

This article reviews the main functions incorporated in the latest version of the source language for the ANALITIK programming system. These functions are intended as transformation tools for nonnumerical models and problems, which are usually represented by systems of symbolic expressions of arbitrary length with a hierarchical structure. Such problems are often connected with nonlinear dependences and oscillating functions, which require multiple integration and differentiation, opening of parentheses, reduction of simmilar terms, various simplifications, etc. Such transformations are available in the languages of the ANALITIK family, REDUCE, Formac, Lisp, MACSYMA, Mathematica, and others. Languages of the ANALITIK family, and especially ANALITIK-93, are distinguished by greater generality and a higher level of intelligence, which is determined by an advanced automatic recognition system of functional properties of the objects being transformed and by a developed interactive system.

Gorovoi, V.D.; Klimenko, V.P.; Fishman, Yu.S.

1995-09-01

9

A Tool for Medical Research  

NASA Technical Reports Server (NTRS)

California Measurements, Inc.'s PC-2 Aerosol Particle Analyzer, developed by William Chiang, a former Jet Propulsion Laboratory (JPL) engineer, was used in a study to measure the size of particles in the medical environment. Chiang has a NASA license for the JPL crystal oscillator technology and originally built the instrument for atmospheric research. In the operating room, it enabled researchers from the University of California to obtain multiple sets of data repeatedly and accurately. The study concluded that significant amounts of aerosols are generated during surgery when power tools are employed, and most of these are in the respirable size. Almost all contain blood and are small enough to pass through surgical masks. Research on the presence of blood aerosols during oral surgery had similar results. Further studies are planned to determine the possibility of HIV transmission during surgery, and the PC-2H will be used to quantify blood aerosols.

1992-01-01

10

Tool for Ranking Research Options  

NASA Technical Reports Server (NTRS)

Tool for Research Enhancement Decision Support (TREDS) is a computer program developed to assist managers in ranking options for research aboard the International Space Station (ISS). It could likely also be adapted to perform similar decision-support functions in industrial and academic settings. TREDS provides a ranking of the options, based on a quantifiable assessment of all the relevant programmatic decision factors of benefit, cost, and risk. The computation of the benefit for each option is based on a figure of merit (FOM) for ISS research capacity that incorporates both quantitative and qualitative inputs. Qualitative inputs are gathered and partly quantified by use of the time-tested analytical hierarchical process and used to set weighting factors in the FOM corresponding to priorities determined by the cognizant decision maker(s). Then by use of algorithms developed specifically for this application, TREDS adjusts the projected benefit for each option on the basis of levels of technical implementation, cost, and schedule risk. Based partly on Excel spreadsheets, TREDS provides screens for entering cost, benefit, and risk information. Drop-down boxes are provided for entry of qualitative information. TREDS produces graphical output in multiple formats that can be tailored by users.

Ortiz, James N.; Scott, Kelly; Smith, Harold

2005-01-01

11

Ecosystem Indicators and Tools in the Gulf of Maine  

EPA Science Inventory

The Gulf of Maine Council on the Marine Environment is a U.S.-Canadian partnership of government and non-government organizations focused on the health, environmental quality and productivity of the Gulf of Maine. In 2006, the Ecosystem Indicator Partnership (ESIP) commenced acti...

12

The Value of Open Source Software Tools in Qualitative Research  

ERIC Educational Resources Information Center

In an era of global networks, researchers using qualitative methods must consider the impact of any software they use on the sharing of data and findings. In this essay, I identify researchers' main areas of concern regarding the use of qualitative software packages for research. I then examine how open source software tools, wherein the publisher…

Greenberg, Gary

2011-01-01

13

University Knowledge Management Tool for Academic Research Activity Evaluation  

Microsoft Academic Search

The implementation of an efficient university knowledge management system involves the de-velopment of several software tools that assist the decision making process for the three main activities of a university: teaching, research, and management. Artificial intelligence provides a variety of techniques that can be used by such tools: machine learning, data mining, text mining, knowledge based systems, expert systems, case-based

Mihaela OPREA

2011-01-01

14

Redesigning Informed Consent Tools for Specific Research  

Microsoft Academic Search

Consent tools for health research generally are designed without contextual or linguistic factors in mind. This is especially true of university-based research. This case history details our design team's efforts to transform one generic consent form into a set of multimodal tools that will increase patients' understanding of and participation in a medical study.

David Wright

2012-01-01

15

Maine Cooperative Fish and Wildlife Research Unit and Department of Wildlife Ecology, University of Maine  

E-print Network

Maine Cooperative Fish and Wildlife Research Unit and Department of Wildlife Ecology, University Fisheries and Wildlife United States Geological Survey United States Fish and Wildlife Service Wildlife of this report in any way is withheld pending specific authorization from the Leader, Maine Cooperative Fish

Thomas, Andrew

16

Scalable Combinatorial Tools for Health Disparities Research  

PubMed Central

Despite staggering investments made in unraveling the human genome, current estimates suggest that as much as 90% of the variance in cancer and chronic diseases can be attributed to factors outside an individual’s genetic endowment, particularly to environmental exposures experienced across his or her life course. New analytical approaches are clearly required as investigators turn to complicated systems theory and ecological, place-based and life-history perspectives in order to understand more clearly the relationships between social determinants, environmental exposures and health disparities. While traditional data analysis techniques remain foundational to health disparities research, they are easily overwhelmed by the ever-increasing size and heterogeneity of available data needed to illuminate latent gene x environment interactions. This has prompted the adaptation and application of scalable combinatorial methods, many from genome science research, to the study of population health. Most of these powerful tools are algorithmically sophisticated, highly automated and mathematically abstract. Their utility motivates the main theme of this paper, which is to describe real applications of innovative transdisciplinary models and analyses in an effort to help move the research community closer toward identifying the causal mechanisms and associated environmental contexts underlying health disparities. The public health exposome is used as a contemporary focus for addressing the complex nature of this subject. PMID:25310540

Langston, Michael A.; Levine, Robert S.; Kilbourne, Barbara J.; Rogers, Gary L.; Kershenbaum, Anne D.; Baktash, Suzanne H.; Coughlin, Steven S.; Saxton, Arnold M.; Agboto, Vincent K.; Hood, Darryl B.; Litchveld, Maureen Y.; Oyana, Tonny J.; Matthews-Juarez, Patricia; Juarez, Paul D.

2014-01-01

17

Scalable combinatorial tools for health disparities research.  

PubMed

Despite staggering investments made in unraveling the human genome, current estimates suggest that as much as 90% of the variance in cancer and chronic diseases can be attributed to factors outside an individual's genetic endowment, particularly to environmental exposures experienced across his or her life course. New analytical approaches are clearly required as investigators turn to complicated systems theory and ecological, place-based and life-history perspectives in order to understand more clearly the relationships between social determinants, environmental exposures and health disparities. While traditional data analysis techniques remain foundational to health disparities research, they are easily overwhelmed by the ever-increasing size and heterogeneity of available data needed to illuminate latent gene x environment interactions. This has prompted the adaptation and application of scalable combinatorial methods, many from genome science research, to the study of population health. Most of these powerful tools are algorithmically sophisticated, highly automated and mathematically abstract. Their utility motivates the main theme of this paper, which is to describe real applications of innovative transdisciplinary models and analyses in an effort to help move the research community closer toward identifying the causal mechanisms and associated environmental contexts underlying health disparities. The public health exposome is used as a contemporary focus for addressing the complex nature of this subject. PMID:25310540

Langston, Michael A; Levine, Robert S; Kilbourne, Barbara J; Rogers, Gary L; Kershenbaum, Anne D; Baktash, Suzanne H; Coughlin, Steven S; Saxton, Arnold M; Agboto, Vincent K; Hood, Darryl B; Litchveld, Maureen Y; Oyana, Tonny J; Matthews-Juarez, Patricia; Juarez, Paul D

2014-01-01

18

Research as an educational tool  

SciTech Connect

Our students have participated in original group research projects focused on the natural environment which culminate in a written manuscript published in-house, and an oral presentation to peers, faculty, and the university community. Our goal has been to develop their critical thinking skills so that they will be more successful in high school and college. We have served ninety-three students (47.1% white, 44.1% black, 5.4% hispanic, 2.2% American Indian, 1.2% asian) from an eight state region in the southeast over the past three years. Thirty-one students have graduated from high school with over 70% enrolled in college and another thirty-four are seniors this year. We are tracking students` progress in college and are developing our own critical thinking test to measure the impact of our program. Although preliminary, the results from the critical thinking test indicated that students are often prone to logical errors; however, higher levels of critical thinking were observed on items which raised issues that conflicted with students` pre-existing beliefs.

Neff, R.; Perlmutter, D.; Klaczynski, P. [Western Carolina Univ., Cullowhee, NC (United States)] [and others

1994-12-31

19

The Maine Garlic Project: A Participatory Research and Education Program  

ERIC Educational Resources Information Center

Participatory research is a useful technique for collecting basic data over a large geographic area. Garlic production was chosen as a participatory research study focus in Maine. Project participants (285) received bulbs to plant, monitored their crop, and reported data online. Participants received a monthly educational newsletter to improve…

Fuller, David; Johnson, Steven B.

2013-01-01

20

Bringing Research Tools into the Classroom  

ERIC Educational Resources Information Center

The advancement of computer technology used for research is creating the need to change the way classes are taught in higher education. "Bringing Research Tools into the Classroom" has become a major focus of the work of the Office of Educational Innovation and Technology (OEIT) for the Dean of Undergraduate Education (DUE) at the Massachusetts…

Shubert, Charles; Ceraj, Ivica; Riley, Justin

2009-01-01

21

Augmenting Computational Research Tools in Observational Cosmology  

NASA Astrophysics Data System (ADS)

We present progress toward creating functional programs for data analysis to be used by cosmology researchers. Using Easy Java Simulations (EJS) to rewrite older code used in cosmology research, such as studying light intensity plots of supernovae (J. Moldenhauer & L. Engelhardt (2011)), should prove most beneficial since many computational research tools pertinent to the field are written in FORTRAN, which while useful in terms of computational speed can be limiting in terms of functionality and simplicity to the user.

Stone, Keenan; Moldenhauer, Jacob; Engelhardt, Larry

2012-03-01

22

Evaluating the Performance of Calculus Classes Using Operational Research Tools.  

ERIC Educational Resources Information Center

Compares the efficiency of calculus classes and evaluates two kinds of classes: traditional and others that use computational methods in teaching. Applies quantitative evaluation methods using two operational research tools, multicriteria decision aid methods (mainly using the MACBETH approach) and data development analysis. (Author/YDS)

Soares de Mello, Joao Carlos C. B.; Lins, Marcos P. E.; Soares de Mello, Maria Helena C.; Gomes, Eliane G.

2002-01-01

23

Guoliang Jin -Research Statement My main research interests are software systems, dynamic/static program analysis, and software engineering.  

E-print Network

shifted to multi- core design as its main strategy for continuing performance growth. Nowadays, multi testing [8]; my work on performance bugs includes one of the first comprehensive characteristics studies], and a performance bug patch validation tool [3]. My future research will focus on providing continuous programming

Sheridan, Jennifer

24

Tools for Finding Indexed Accounting Research  

NSDL National Science Digital Library

The American Accounting Association (AAA) lists the print resources and electronic databases where AAA journals are indexed and abstracted at this Tools for Finding Indexed Accounting Research page. The detailed list includes indexing and abstracting devices for a number of journals -- Accounting Horizons, The Accounting Review, Auditing: A Journal of Practice & Theory, Behavioral Research in Accounting, Issues in Accounting Education, Journal of the American Taxation Association, Journal of Information Systems, and the Journal of Management Accounting Research -- with date coverage and full-text information included for each.

25

Tools and collaborative environments for bioinformatics research  

PubMed Central

Advanced research requires intensive interaction among a multitude of actors, often possessing different expertise and usually working at a distance from each other. The field of collaborative research aims to establish suitable models and technologies to properly support these interactions. In this article, we first present the reasons for an interest of Bioinformatics in this context by also suggesting some research domains that could benefit from collaborative research. We then review the principles and some of the most relevant applications of social networking, with a special attention to networks supporting scientific collaboration, by also highlighting some critical issues, such as identification of users and standardization of formats. We then introduce some systems for collaborative document creation, including wiki systems and tools for ontology development, and review some of the most interesting biological wikis. We also review the principles of Collaborative Development Environments for software and show some examples in Bioinformatics. Finally, we present the principles and some examples of Learning Management Systems. In conclusion, we try to devise some of the goals to be achieved in the short term for the exploitation of these technologies. PMID:21984743

Giugno, Rosalba; Pulvirenti, Alfredo

2011-01-01

26

Inductive knowledge acquisition experience with commercial tools for space shuttle main engine testing  

NASA Technical Reports Server (NTRS)

Since 1984, an effort has been underway at Rocketdyne, manufacturer of the Space Shuttle Main Engine (SSME), to automate much of the analysis procedure conducted after engine test firings. Previously published articles at national and international conferences have contained the context of and justification for this effort. Here, progress is reported in building the full system, including the extensions of integrating large databases with the system, known as Scotty. Inductive knowledge acquisition has proven itself to be a key factor in the success of Scotty. The combination of a powerful inductive expert system building tool (ExTran), a relational data base management system (Reliance), and software engineering principles and Computer-Assisted Software Engineering (CASE) tools makes for a practical, useful and state-of-the-art application of an expert system.

Modesitt, Kenneth L.

1990-01-01

27

Market research companies and new product development tools  

Microsoft Academic Search

This research investigates (1) the share of new product development (NPD) research services in market research (MR) companies’ turnover, (2) MR companies’ awareness and use of NPD tools and the modifications made to these NPD tools, and (3) MR company managers’ perceptions of the influence of client use of commissioned NPD research on client NPD performance. The results from a

Edwin J. Nijssen; Ruud T. Frambach

1998-01-01

28

What would you say your main research interests are?  

E-print Network

for the sake of plugging into and altering metabolic pathways. However, genetic tools and overall understanding of how to manipulate biological systems have now advanced to a point where engineering proteins is just in this field and how data from those studies can be extrapolated for microorganisms other than E.coli? We

Nikolaou, Michael

29

VAO Tools Enhance CANDELS Research Productivity  

NASA Astrophysics Data System (ADS)

The formation of galaxies and their co-evolution with black holes through cosmic time are prominent areas in current extragalactic astronomy. New methods in science research are building upon collaborations between scientists and archive data centers which span large volumes of multi-wavelength and heterogeneous data. A successful example of this form of teamwork is demonstrated by the CANDELS (Cosmic Assembly Near-infrared Deep Extragalactic Legacy Survey) and the Virtual Astronomical Observatory (VAO) collaboration. The CANDELS project archive data provider services are registered and discoverable in the VAO through an innovative web based Data Discovery Tool, providing a drill down capability and cross-referencing with other co-spatially located astronomical catalogs, images and spectra. The CANDELS team is working together with the VAO to define new methods for analyzing Spectral Energy Distributions of galaxies containing active galactic nuclei, and helping to evolve advanced catalog matching methods for exploring images of variable depths, wavelengths and resolution. Through the publication of VOEvents, the CANDELS project is publishing data streams for newly discovered supernovae that are bright enough to be followed from the ground.

Greene, Gretchen; Donley, J.; Rodney, S.; LAZIO, J.; Koekemoer, A. M.; Busko, I.; Hanisch, R. J.; VAO Team; CANDELS Team

2013-01-01

30

University of Maine Integrated Forest Product Refinery (IFPR) Technology Research  

SciTech Connect

This project supported research on science and technology that forms a basis for integrated forest product refinery for co-production of chemicals, fuels and materials using existing forest products industry infrastructure. Clear systems view of an Integrated Forest Product Refinery (IFPR) allowed development of a compelling business case for a small scale technology demonstration in Old Town ME for co-production of biofuels using cellulosic sugars along with pulp for the new owners of the facility resulting in an active project on Integrated Bio-Refinery (IBR) at the Old Town Fuel & Fiber. Work on production of advanced materials from woody biomass has led to active projects in bioplastics and carbon nanofibers. A lease for 40,000 sq. ft. high-bay space has been obtained to establish a Technology Research Center for IFPR technology validation on industrially relevant scale. UMaine forest bioproducts research initiative that began in April 2006 has led to establishment of a formal research institute beginning in March 2010.

Pendse, Hemant P.

2010-11-23

31

Sociometry: Tools for Research and Practice.  

ERIC Educational Resources Information Center

Reviews basic sociometric tools and their analysis, provides information on computer programs to analyze sociometric data, and briefly examines considerations in conducting sociometric investigations. Looks at the social atom (significant others), constructing sociometry questions, and offers an analysis of individual status and interactional…

Treadwell, Thomas W.; Kumar, V. K.; Stein, Steven A.; Prosnick, Kevin

1997-01-01

32

Microfluidic tools for cell biological research  

PubMed Central

Summary Microfluidic technology is creating powerful tools for cell biologists to control the complete cellular microenvironment, leading to new questions and new discoveries. We review here the basic concepts and methodologies in designing microfluidic devices, and their diverse cell biological applications. PMID:21152269

Velve-Casquillas, Guilhem; Le Berre, Mael; Piel, Matthieu; Tran, Phong T.

2010-01-01

33

TECHNOLOGY & TEACHING Using Google Books as a Research Tool  

E-print Network

TECHNOLOGY & TEACHING · Using Google Books as a Research Tool Using Google Books as a Research Tool Google Books -- http://books.google.com -- is the world's largest digital library. As of this past June, Google has scanned approximately 12 million books, making its collection about half the size

Champagne, Frances A.

34

The Child Diary as a Research Tool  

ERIC Educational Resources Information Center

The aim of this article is to introduce the use of the child diary as a method in daily diary research. By describing the research process and detailing its structure, a child diary, a structured booklet in which children's parents and day-care personnel (N = 54 children) reported their observations, was evaluated. The participants reported the…

Lamsa, Tiina; Ronka, Anna; Poikonen, Pirjo-Liisa; Malinen, Kaisa

2012-01-01

35

Action research as culture change tool  

Microsoft Academic Search

Purpose – To report experiences of changing cultures in three Lithuanian schools by means of action research. Design\\/methodology\\/approach – This took the form of action research in the schools. Culture change measured by a culture survey (developed by Harrison and Stokes) in the beginning and towards the end of the three-year change project. Findings – The cultures of the primary

Romualda Marcinkoniene; Tauno Kekäle

2007-01-01

36

Using Wordle as a Supplementary Research Tool  

ERIC Educational Resources Information Center

A word cloud is a special visualization of text in which the more frequently used words are effectively highlighted by occupying more prominence in the representation. We have used Wordle to produce word-cloud analyses of the spoken and written responses of informants in two research projects. The product demonstrates a fast and visually rich way…

McNaught, Carmel; Lam, Paul

2010-01-01

37

Process benchmarking as a market research tool for strategic planning  

Microsoft Academic Search

Process benchmarking partnerships are emerging as a research tool to help small firms to build a competitive advantage against larger rivals. Managers are now beginning to appreciate the need to benchmark the strategically relevant processes in their value chain. Process benchmarking begins with exploratory qualitative research to determine the core processes to be benchmarked. Quantitative research then follows, using an

Deborah Ralston; April Wright; Jaynendra Kumar

2001-01-01

38

Improving Teaching with Collaborative Action Research: An ASCD Action Tool  

ERIC Educational Resources Information Center

Once you've established a professional learning community (PLC), you need to get this ASCD (Association for Supervision and Curriculum Development) action tool to ensure that your PLC stays focused on addressing teaching methods and student learning problems. This ASCD action tool explains how your PLC can use collaborative action research to…

Cunningham, Diane

2011-01-01

39

Research on NC Machine Tool Dynamic Characteristic Considering Processing Dynamics  

Microsoft Academic Search

A method for the machine tool dynamic characteristic modeling and simulation is further presented. This method takes structure and processing dynamics into account, after the structural dynamic characteristic of the machine tool has been studied. A certain gantry-type machining center is used as a research object. First, the structural dynamic model based on finite element analysis (FEA) is built. Through

Xu Dan; Kang Rui; Liu Qiang

2010-01-01

40

Aligning Web-Based Tools to the Research Process Cycle: A Resource for Collaborative Research Projects  

ERIC Educational Resources Information Center

Using John Creswell's Research Process Cycle as a framework, this article describes various web-based collaborative technologies useful for enhancing the organization and efficiency of educational research. Visualization tools (Cacoo) assist researchers in identifying a research problem. Resource storage tools (Delicious, Mendeley, EasyBib)…

Price, Geoffrey P.; Wright, Vivian H.

2012-01-01

41

RESEARCH ARTICLE Participatory design of agricultural decision support tools  

E-print Network

RESEARCH ARTICLE Participatory design of agricultural decision support tools: taking account decision support systems, we propose methodological elements for conducting the participatory design all the participants and allows them to develop cross-learning processes. We discuss how these two

Paris-Sud XI, Université de

42

Making Wavesat the University of Maine Darling Marine Center More cutting-edge research inside  

E-print Network

2008 Making Wavesat the University of Maine Darling Marine Center More cutting-edge research inside newsletter of the University of Maine Darling Marine Center. Dr. Kevin J. Eckelbarger Director Tim Miller

Boss, Emmanuel S.

43

Cognitive Environment Simulation as a Tool for Modeling Human Performance and Reliability. Main Report.  

National Technical Information Service (NTIS)

The U.S. Nuclear Regulatory Commission is sponsoring a program to develop improved methods to model cognitive behavior of nuclear power plant (NPP) personnel. A tool called Cognitive Environment Simulation (CES) was developed for simulating how people for...

D. D. Woods, H. E. Pople, E. M. Roth

1990-01-01

44

Focus Group Research: A Tool for the Student Affairs Professional.  

ERIC Educational Resources Information Center

Explores limits of quantitative research methods and introduces qualitative approach, focus groups, as alternative information-collection tool for student personnel administrators. Presents two research projects where focus groups were used. Maintains that focus group approach has several advantages, including cost effectiveness, emphasis on…

Jacobi, Maryann

1991-01-01

45

Profiling Academic Research on Digital Games Using Text Mining Tools  

Microsoft Academic Search

Academic research on digital games has been conducted for over 30 years. However, the abundance of disciplines conducting research on the topic makes it challenging for the interested to get a holistic and comprehensive account of past digital game studies. Yet, sophisticated text mining tools designed for structured science information resources, such as the ISI Web of Science or INSPEC,

Johanna Bragge; Jan Storgårds

2007-01-01

46

Computational fluid dynamics as a design tool for the hot gas manifold of the Space Shuttle Main Engine  

NASA Technical Reports Server (NTRS)

The paper discusses the application of computational fluid dynamics as a design tool for the Hot Gas Manifold of the Space Shuttle Main Engine. An improved Hot Gas Manifold configuration was arrived at computationally. This configuration was then built and air flow tested. Testing verified this configuration to be a substantial improvement over existing flight designs.

Ziebarth, J. P.; Barson, S.; Rosen, R.

1986-01-01

47

STUDY PROTOCOL Open Access "Card sorting": a tool for research in ethics on  

E-print Network

STUDY PROTOCOL Open Access "Card sorting": a tool for research in ethics on treatment decision be decided: to treat or not to treat? Which arguments are used for decision-making? These are mainly ethical with the dilemma of which is the least bad decision in relation to the person's interests. Should an assessment

Paris-Sud XI, Université de

48

Databases and registers: useful tools for research, no studies.  

PubMed

There are many misunderstandings about databases. Database is a commonly misused term in reference to any set of data entered into a computer. However, true databases serve a main purpose, organising data. They do so by establishing several layers of relationships; databases are hierarchical. Databases commonly organise data over different levels and over time, where time can be measured as the time between visits, or between treatments, or adverse events, etc. In this sense, medical databases are closely related to longitudinal observational studies, as databases allow the introduction of data on the same patient over time. Basically, we could establish four types of databases in medicine, depending on their purpose: (1) administrative databases, (2) clinical databases, (3) registers, and (4) study-oriented databases. But a database is a useful tool for a large variety of studies, not a type of study itself. Different types of databases serve very different purposes, and a clear understanding of the different research designs mentioned in this paper would prevent many of the databases we launch from being just a lot of work and very little science. PMID:24509895

Curbelo, Rafael J; Loza, Estíbaliz; de Yébenes, Maria Jesús García; Carmona, Loreto

2014-04-01

49

Overview of EPA Research On Condition Assessment of Drinking Water Mains  

EPA Science Inventory

This slide presentation provides an overview of condition assessment research that is part of EPA Office of Research and Development?s Aging Water Infrastructure Research Plan (AWIRP). The primary focus is on a water main condition assessment technology forum and associated whit...

50

RESEARCH TOOLS KNMI CLIMATE EXPLORER: A WEB-BASED RESEARCH TOOL FOR  

E-print Network

data and derived time series, to examine the climatic signal in uploaded high- resolution paleoclimate further demonstrate the value of Climate Explorer for high-resolution paleoclimate research using such as climate change research (van Oldenborgh et al. 2009) and the paleoclimate research community current- ly

Haak, Hein

51

A web service based tool to plan atmospheric research flights  

NASA Astrophysics Data System (ADS)

We present a web service based tool for the planning of atmospheric research flights. The tool provides online access to horizontal maps and vertical cross-sections of numerical weather prediction data and in particular allows the interactive design of a flight route in direct relation to the predictions. It thereby fills a crucial gap in the set of currently available tools for using data from numerical atmospheric models for research flight planning. A distinct feature of the tool is its lightweight, web service based architecture, requiring only commodity hardware and a basic Internet connection for deployment. Access to visualisations of prediction data is achieved by using an extended version of the Open Geospatial Consortium Web Map Service (WMS) standard, a technology that has gained increased attention in meteorology in recent years. With the WMS approach, we avoid the transfer of large forecast model output datasets while enabling on-demand generated visualisations of the predictions at campaign sites with limited Internet bandwidth. Usage of the Web Map Service standard also enables access to third-party sources of georeferenced data. We have implemented the software using the open-source programming language Python. In the present article, we describe the architecture of the tool. As an example application, we discuss a case study research flight planned for the scenario of the 2010 Eyjafjalla volcano eruption. Usage and implementation details are provided as Supplement.

Rautenhaus, M.; Bauer, G.; Dörnbrack, A.

2012-01-01

52

A web service based tool to plan atmospheric research flights  

NASA Astrophysics Data System (ADS)

We present a web service based tool for the planning of atmospheric research flights. The tool provides online access to horizontal maps and vertical cross-sections of numerical weather prediction data and in particular allows the interactive design of a flight route in direct relation to the predictions. It thereby fills a crucial gap in the set of currently available tools for using data from numerical atmospheric models for research flight planning. A distinct feature of the tool is its lightweight, web service based architecture, requiring only commodity hardware and a basic Internet connection for deployment. Access to visualisations of prediction data is achieved by using an extended version of the Open Geospatial Consortium Web Map Service (WMS) standard, a technology that has gained increased attention in meteorology in recent years. With the WMS approach, we avoid the transfer of large forecast model output datasets while enabling on-demand generated visualisations of the predictions at campaign sites with limited Internet bandwidth. Usage of the Web Map Service standard also enables access to third-party sources of georeferenced data. We have implemented the software using the open-source programming language Python. In the present article, we describe the architecture of the tool. As an example application, we discuss a case study research flight planned for the scenario of the 2010 Eyjafjalla volcano eruption. Usage and implementation details are provided as Supplement.

Rautenhaus, M.; Bauer, G.; Dörnbrack, A.

2011-09-01

53

Measurement and Research Tools. Symposium 37. [AHRD Conference, 2001].  

ERIC Educational Resources Information Center

This symposium on measurement and research tools consists of three presentations. "An Examination of the Multiple Intelligences Developmental Assessment Scales (MIDAS)" (Albert Wiswell et al.) explores MIDAS's psychometric saliency. Findings indicates this instrument represents an incomplete attempt to develop a valid assessment of multiple…

2001

54

Neutron interferometry as a new tool in condensed matter research  

Microsoft Academic Search

Since perfect crystal interferometry has become operational it has been used as a new tool in fundamental-, nuclear- and solid state physics. Although most work has been spent up till now for fundamental- and nuclear physics applications, several test measurements exist also in the field of condensed matter research. These investigations deal with metal-hydrogen systems, precipitates in alloys, the domain

H. Rauch; E. Seidl

1987-01-01

55

Analyzing Online Teacher Networks: Cyber Networks Require Cyber Research Tools  

ERIC Educational Resources Information Center

The authors argue that conceptual and methodological limitations in existing research approaches severely hamper theory building and empirical exploration of teacher learning and collaboration through cyber-enabled networks. They conclude that new frameworks, tools, and techniques are needed to understand and maximize the benefits of teacher…

Schlager, Mark S.; Farooq, Umer; Fusco, Judith; Schank, Patricia; Dwyer, Nathan

2009-01-01

56

Database Advisor: A New Tool for K-12 Research Projects.  

ERIC Educational Resources Information Center

The Database Advisor (DBA) is a tool designed to guide users to the most appropriate World Wide Web-based databases for their research. Developed in 1997 by the Science Libraries at the University of California, San Diego (UCSD), DBA is a Web-based front-end to bibliographic and full-text databases to which UCSD has remote access. DBA allows the…

Berteaux, Susan S.; Strong, Sandra S.

57

NoteStar: A Project Based Learning Research Tool  

NSDL National Science Digital Library

This resource is a free tool that helps students organize data, notes, and citations obtained from project-based investigations and research. By dragging the NoteStar icon to the toolbar, users can save citations and other digital data with one click. The tool also allows them to create personal notations for future reference or sharing with partners. The tool is available only to registered teacher-users, who will do the initial set-up. Students use a password to access their accounts, but are not required to disclose personal information. The teacher can monitor any student's progress at any time. This resource was intended for use with ThinkTank, a related cost-free tool that helps students develop and narrow research questions. Outlines created in ThinkTank can be exported to NoteStar. NoteStar is part of the collection of online tools available through 4Teachers.org. ***PLEASE NOTE: Some of the pages within this resource are sponsored by commercial vendors. The Physics Front neither endorses nor recommends products for commercial sale.

2009-11-19

58

Technical phosphoproteomic and bioinformatic tools useful in cancer research  

PubMed Central

Reversible protein phosphorylation is one of the most important forms of cellular regulation. Thus, phosphoproteomic analysis of protein phosphorylation in cells is a powerful tool to evaluate cell functional status. The importance of protein kinase-regulated signal transduction pathways in human cancer has led to the development of drugs that inhibit protein kinases at the apex or intermediary levels of these pathways. Phosphoproteomic analysis of these signalling pathways will provide important insights for operation and connectivity of these pathways to facilitate identification of the best targets for cancer therapies. Enrichment of phosphorylated proteins or peptides from tissue or bodily fluid samples is required. The application of technologies such as phosphoenrichments, mass spectrometry (MS) coupled to bioinformatics tools is crucial for the identification and quantification of protein phosphorylation sites for advancing in such relevant clinical research. A combination of different phosphopeptide enrichments, quantitative techniques and bioinformatic tools is necessary to achieve good phospho-regulation data and good structural analysis of protein studies. The current and most useful proteomics and bioinformatics techniques will be explained with research examples. Our aim in this article is to be helpful for cancer research via detailing proteomics and bioinformatic tools. PMID:21967744

2011-01-01

59

SEACOIN – An Investigative Tool for Biomedical Informatics Researchers  

PubMed Central

Peer-reviewed scientific literature is a prime source for accessing knowledge in the biomedical field. Its rapid growth and diverse domain coverage require systematic efforts in developing interactive tools for efficiently searching and summarizing current advances for acquiring knowledge and referencing, and for furthering scientific discovery. Although information retrieval systems exist, the conventional tools and systems remain difficult for biomedical investigators to use. There remain gaps even in the state-of-the-art systems as little attention has been devoted to understanding the needs of biomedical researchers. Our work attempts to bridge the gap between the needs of biomedical users and systems design efforts. We first study the needs of users and then design a simple visual analytic application tool, SEACOIN. A key motivation stems from biomedical researchers’ request for a “simple interface” that is suitable for novice users in information technology. The system minimizes information overload, and allows users to search easily even in time-constrained situations. Users can manipulate the depth of information according to the purpose of usage. SEACOIN enables interactive exploration and filtering of search results via “metamorphose topological visualization” and “tag cloud,” visualization tools that are commonly used in social network sites. We illustrate SEACOIN’s usage through applications on PubMed publications on heart disease, cancer, Alzheimer’s disease, diabetes, and asthma. PMID:22195132

Lee, Eva K.; Lee, Hee-Rin; Quarshie, Alexander

2011-01-01

60

CaMKII inhibitors: from research tools to therapeutic agents  

PubMed Central

The cardiac field has benefited from the availability of several CaMKII inhibitors serving as research tools to test putative CaMKII pathways associated with cardiovascular physiology and pathophysiology. Successful demonstrations of its critical pathophysiological roles have elevated CaMKII as a key target in heart failure, arrhythmia, and other forms of heart disease. This has caught the attention of the pharmaceutical industry, which is now racing to develop CaMKII inhibitors as safe and effective therapeutic agents. While the first generation of CaMKII inhibitor development is focused on blocking its activity based on ATP binding to its catalytic site, future inhibitors can also target sites affecting its regulation by Ca2+/CaM or translocation to some of its protein substrates. The recent availability of crystal structures of the kinase in the autoinhibited and activated state, and of the dodecameric holoenzyme, provides insights into the mechanism of action of existing inhibitors. It is also accelerating the design and development of better pharmacological inhibitors. This review examines the structure of the kinase and suggests possible sites for its inhibition. It also analyzes the uses and limitations of current research tools. Development of new inhibitors will enable preclinical proof of concept tests and clinical development of successful lead compounds, as well as improved research tools to more accurately examine and extend knowledge of the role of CaMKII in cardiac health and disease. PMID:24600394

Pellicena, Patricia; Schulman, Howard

2014-01-01

61

A web service based tool to plan atmospheric research flights  

NASA Astrophysics Data System (ADS)

We present a web service based tool for the planning of atmospheric research flights. The tool, which we call the "Mission Support System" (MSS), provides online access to horizontal maps and vertical cross-sections of numerical weather prediction data and in particular allows the interactive design of a flight route in direct relation to the predictions. It thereby fills a crucial gap in the set of currently available tools for using data from numerical atmospheric models for research flight planning. A distinct feature of the tool is its lightweight, web service based architecture, requiring only commodity hardware and a basic Internet connection for deployment. Access to visualisations of prediction data is achieved by using an extended version of the Open Geospatial Consortium Web Map Service (WMS) standard. With the WMS approach, we avoid the transfer of large forecast model output datasets while enabling on-demand generated visualisations of the predictions at campaign sites with limited Internet bandwidth. Usage of the Web Map Service standard also enables access to third-party sources of georeferenced data. The MSS is focused on the primary needs of mission scientists responsible for planning a research flight, addressing in particular the following requirements: (1) interactive exploration of available atmospheric forecasts, (2) interactive flight planning in relation to these forecasts, (3) computation of expected flight performance to assess the technical feasibility (in terms of total distance and vertical profile) of a flight, (4) no transfer of large forecast data files to the campaign site to allow deployment at remote locations and (5) low demand on hardware resources. We have implemented the software using the open-source programming language Python.

Rautenhaus, M.; Dörnbrack, A.

2012-04-01

62

Research gaps for three main tropical diseases in the People's Republic of China  

PubMed Central

This scoping review analyzes the research gaps of three diseases: schistosomiasis japonica, malaria and echinococcosis. Based on available data in the P.R. China, we highlight the gaps between control capacity and prevalence levels, and between diagnostic/drug development and population need for treatment at different stages of the national control programme. After reviewing the literature from 848 original studies and consultations with experts in the field, the gaps were identified as follows. Firstly, the malaria research gaps include (i) deficiency of active testing in the public community and no appropriate technique to evaluate elimination, (ii) lack of sensitive diagnostic tools for asymptomatic patients, (iii) lack of safe drugs for mass administration. Secondly, gaps in research of schistosomiasis include (i) incongruent policy in the implementation of integrated control strategy for schistosomiasis, (ii) lack of effective tools for Oncomelania sp. snail control, (iii) lack of a more sensitive and cheaper diagnostic test for large population samples, (iv) lack of new drugs in addition to praziquantel. Thirdly, gaps in research of echinococcosis include (i) low capacity in field epidemiology studies, (ii) lack of sanitation improvement studies in epidemic areas, (iii) lack of a sensitivity test for early diagnosis, (iv) lack of more effective drugs for short-term treatment. We believe these three diseases can eventually be eliminated in mainland China if all the research gaps are abridged in a short period of time. PMID:23895635

2013-01-01

63

Scientific research tools as an aid to Antarctic logistics  

NASA Astrophysics Data System (ADS)

Logistics have always been a vital part of polar exploration and research. The more efficient those logistics can be made, the greater the likelihood that research programmes will be delivered on time, safely and to maximum scientific effectiveness. Over the last decade, the potential for symbiosis between logistics and some of the scientific research methods themselves, has increased remarkably; suites of scientific tools can help to optimise logistic efforts, thereby enhancing the effectiveness of further scientific activity. We present one recent example of input to logistics from scientific activities, in support of the NERC iSTAR Programme, a major ice sheet research effort in West Antarctica. We used data output from a number of research tools, spanning a range of techniques and international agencies, to support the deployment of a tractor-traverse system into a remote area of mainland Antarctica. The tractor system was deployed from RRS Ernest Shackleton onto the Abbot Ice Shelf then driven inland to the research area in Pine Island Glacier Data from NASA ICEBRIDGE were used to determine the ice-front freeboard and surface gradients for the traverse route off the ice shelf and onwards into the continent. Quickbird high resolution satellite imagery provided clear images of route track and some insight into snow surface roughness. Polarview satellite data gave sea ice information in the Amundsen Sea, both the previous multi-annual historical characteristics and for real-time information during deployment. Likewise meteorological data contributed historical and information and was used during deployment. Finally, during the tractors' inland journey, ground-based high frequency radar was used to determine a safe, crevasse-free route.

Dinn, Michael; Rose, Mike; Smith, Andrew; Fleming, Andrew; Garrod, Simon

2013-04-01

64

Main Trends of Research in the Social and Human Sciences, Part 1: Social Sciences.  

ERIC Educational Resources Information Center

This volume is the result of a study, initiated by United Nations Educational, Scientific and Cultural Organization (UNESCO), to report on the main trends of social sciences research, not on the results achieved. Part I contains an examination of the present state and perspectives for development of the disciplines of sociology (Lazarsfeld),…

United Nations Educational, Scientific, and Cultural Organization, Paris (France).

65

STEAM ENHANCED REMEDIATION RESEARCH FOR DNAPL IN FRACTURED ROCK, LORING AIR FORCE BASE, LIMESTONE, MAINE  

EPA Science Inventory

This report details a research project on Steam Enhanced Remediation (SER) for the recovery of volatile organic compounds from fractured limestone that was carried out at the Quarry at the former Loring Air Force Base in Limestone, Maine. This project was carried out by USEPA, Ma...

66

Monte Carlo Simulation as a Research Management Tool  

SciTech Connect

Monte Carlo simulation provides a research manager with a performance monitoring tool to supplement the standard schedule- and resource-based tools such as the Program Evaluation and Review Technique (PERT) and Critical Path Method (CPM). The value of the Monte Carlo simulation in a research environment is that it 1) provides a method for ranking competing processes, 2) couples technical improvements to the process economics, and 3) provides a mechanism to determine the value of research dollars. In this paper the Monte Carlo simulation approach is developed and applied to the evaluation of three competing processes for converting lignocellulosic biomass to ethanol. The technique is shown to be useful for ranking the processes and illustrating the importance of the timeframe of the analysis on the decision process. The results show that acid hydrolysis processes have higher potential for near-term application (2-5 years), while the enzymatic hydrolysis approach has an equal chance to be competitive in the long term (beyond 10 years).

Douglas, L. J.

1986-06-01

67

Vaccinia Virus: A Tool for Research and Vaccine Development  

NASA Astrophysics Data System (ADS)

Vaccinia virus is no longer needed for smallpox immunization, but now serves as a useful vector for expressing genes within the cytoplasm of eukaryotic cells. As a research tool, recombinant vaccinia viruses are used to synthesize biologically active proteins and analyze structure-function relations, determine the targets of humoral- and cell-mediated immunity, and investigate the immune responses needed for protection against specific infectious diseases. When more data on safety and efficacy are available, recombinant vaccinia and related poxviruses may be candidates for live vaccines and for cancer immunotherapy.

Moss, Bernard

1991-06-01

68

MRC: Research Tools and Skills Grade 3-5  

NSDL National Science Digital Library

This is a lesson about research tools and skills. Learners will explore the features of Mars through a demonstration of Google Earth Mars, gather, and analyze data from multiple sources on the internet as well as print sources, develop and use strategies for reading informational text to systematically find information, understand that Earth and Mars have similar geological features. The lesson uses the 5E instructional model and includes: TEKS Details (Texas Standards alignment), Essential Question, Science Notebook, Vocabulary Definitions for Students, Vocabulary Definitions for Teachers, two Vocabulary Cards, and a reading strategy supplement. This is lesson 3 as part of the Mars Rover Celebration Unit, a six week long curriculum.

69

Fish in behavior research: unique tools with a great promise!  

PubMed

Fish represent the most diverse class of vertebrates on Earth and also an unprecedented, but as of yet still largely untapped, resource for comparative analyses that can illuminate answers to questions about both how organisms work and how they evolved. The current review is a general discussion of some of the basic principles of why adding new species such as fish to the short list of biomedical model organisms (mainly the house mouse and the rat) has merit. In addition to the general points, it also reviews some questions about a newcomer, the zebrafish, which is rapidly gaining popularity in brain and behavior research. It discusses some examples demonstrating the advantages and disadvantages of the zebrafish mainly in the context of biomedical research. It is followed by other articles that further elaborate on these questions. PMID:24768578

Gerlai, Robert

2014-08-30

70

Data Ferret: Federal Electronic Research and Review Extraction Tool  

NSDL National Science Digital Library

This new service of the US Census Bureau allows researchers to extract information from the Current Population Surveys March 1995 and 1996 supplements and CPS Displaced Workers 1996 data. For CPS March supplements, pre-formatted macrodata tables are available in nine categories at present, including health insurance, family income, and poverty. But the real power of the site, especially for researchers, is the ability to query and extract microdata records from both datasets, and either view this microdata or download it as ASCII text (user's choice as to delimiter format), with crosstabs or frequencies, or as SAS datasets. Presently available datasets are just the beginning of what will be a much larger searchable statistics database, and "FERRET will be one of the tools in the Census Bureau's Data Access and Dissemination System (DADS)," a data retrieval system "being developed to provide better access to all census data." Note that users must supply an email address before using the system.

71

Nanobody-based products as research and diagnostic tools.  

PubMed

Since the serendipitous discovery 20 years ago of bona fide camelid heavy-chain antibodies, their single-domain antigen-binding fragments, known as VHHs or nanobodies, have received a progressively growing interest. As a result of the beneficial properties of these stable recombinant entities, they are currently highly valued proteins for multiple applications, including fundamental research, diagnostics, and therapeutics. Today, with the original patents expiring, even more academic and industrial groups are expected to explore innovative VHH applications. Here, we provide a thorough overview of novel implementations of VHHs as research and diagnostic tools, and of the recently evaluated production platforms for several VHHs and VHH-derived antibody formats. PMID:24698358

De Meyer, Thomas; Muyldermans, Serge; Depicker, Ann

2014-05-01

72

YouTube as a research tool: three approaches.  

PubMed

The present paper provides empirical data to support the use of social media as research environment. YouTube was chosen as a most appropriate format to target adolescents in experimental and cross-sectional designs given its popularity as well as its plasticity. We uniquely applied the YouTube format as (a) an environment to present manipulated media materials in controlled experimental designs; (b) an environment to study effects of peer feedback on various media contents; (c) a format to design a media-based questionnaire, specifically, the Media, Morals and Youth Questionnaire (MMaYQue). Various studies have been conducted that demonstrate the appropriateness of our YouTube transformations for each of these three purposes. The focus in the present paper is on the methodology of these studies to illustrate how we effectively transformed YouTube as a research tool. PMID:23659721

Konijn, Elly A; Veldhuis, Jolanda; Plaisier, Xanthe S

2013-09-01

73

Operations other than war: Requirements for analysis tools research report  

SciTech Connect

This report documents the research effort to determine the requirements for new or improved analysis tools to support decisions at the strategic and operational levels for military Operations Other than War (OOTW). The work was performed for the Commander in Chief, U.S. Pacific Command (USCINCPAC). The data collection was based on workshops attended by experts in OOTWs: analysis personnel from each of the Combatant Commands, the Services, the Office of the Secretary of Defense (OSD), the Joint Staff, and other knowledgeable personnel. Further data were gathered from other workshops and conferences and from the literature. The results of this research begin with the creation of a taxonomy of OOTWs: categories of operations, attributes of operations, and tasks requiring analytical support. The tasks are connected to the Joint Staff`s Universal Joint Task List (UJTL). Historical OOTWs are analyzed to produce frequency distributions by category and responsible CINC. The analysis products are synthesized into a list of requirements for analytical tools and definitions of the requirements. The report concludes with a timeline or roadmap for satisfying the requirements.

Hartley, D.S. III

1996-12-01

74

Research on the Collaborative Design Technology for Airplane Tooling  

Microsoft Academic Search

Considering the characteristic and difficulty of airplane tooling design that the correlation is complicated and cooperation is difficult, the collaborative design framework for airplane tooling is constructed, and the key technologies, including the technology of collaboration between tooling design and airplane product design, the collaborative design technology of airplane tooling application model, the correlative design technology of airplane tooling structure,

Yingguang Li; Zhiyi Pan; Ruijie Yan; Wenhe Liao

2007-01-01

75

Intellectual Property: a powerful tool to develop biotech research  

PubMed Central

Summary Today biotechnology is perhaps the most important technology field because of the strong health and food implications. However, due to the nature of said technology, there is the need of a huge amount of investments to sustain the experimentation costs. Consequently, investors aim to safeguard as much as possible their investments. Intellectual Property, and in particular patents, has been demonstrated to actually constitute a powerful tool to help them. Moreover, patents represent an extremely important means to disclose biotechnology inventions. Patentable biotechnology inventions involve products as nucleotide and amino acid sequences, microorganisms, processes or methods for modifying said products, uses for the manufacture of medicaments, etc. There are several ways to protect inventions, but all follow the three main patentability requirements: novelty, inventive step and industrial application. PMID:21255349

Giugni, Diego; Giugni, Valter

2010-01-01

76

Technology, safety, and costs of decommissioning reference nuclear research and test reactors. Main report  

SciTech Connect

Safety and Cost Information is developed for the conceptual decommissioning of two representative licensed nuclear research and test reactors. Three decommissioning alternatives are studied to obtain comparisons between costs (in 1981 dollars), occupational radiation doses, potential radiation dose to the public, and other safety impacts. The alternatives considered are: DECON (immediate decontamination), SAFSTOR (safe storage followed by deferred decontamination), and ENTOMB (entombment). The study results are presented in two volumes. Volume 1 (Main Report) contains the results in summary form.

Konzek, G.J.; Ludwick, J.D.; Kennedy, W.E. Jr.; Smith, R.I.

1982-03-01

77

NASA Human Research Wiki - An Online Collaboration Tool  

NASA Technical Reports Server (NTRS)

In preparation for exploration-class missions, the Exploration Medical Capability (ExMC) element of NASA's Human Research Program (HRP) has compiled a large evidence base, which previously was available only to persons within the NASA community. The evidence base is comprised of several types of data, for example: information on more than 80 medical conditions which could occur during space flight, derived from several sources (including data on incidence and potential outcomes of these medical conditions, as captured in the Integrated Medical Model's Clinical Finding Forms). In addition, approximately 35 gap reports are included in the evidence base, identifying current understanding of the medical challenges for exploration, as well as any gaps in knowledge and/or technology that would need to be addressed in order to provide adequate medical support for these novel missions. In an effort to make the ExMC information available to the general public and increase collaboration with subject matter experts within and outside of NASA, ExMC has developed an online collaboration tool, very similar to a wiki, titled the NASA Human Research Wiki. The platform chosen for this data sharing, and the potential collaboration it could generate, is a MediaWiki-based application that would house the evidence, allow "read only" access to all visitors to the website, and editorial access to credentialed subject matter experts who have been approved by the Wiki's editorial board. Although traditional wikis allow users to edit information in real time, the NASA Human Research Wiki includes a peer review process to ensure quality and validity of information. The wiki is also intended to be a pathfinder project for other HRP elements that may want to use this type of web-based tool. The wiki website will be released with a subset of the data described and will continue to be populated throughout the year.

Barr, Y. R.; Rasbury, J.; Johnson, J.; Barsten, K.; Saile, L.; Watkins, S. D.

2011-01-01

78

Researchers develop new search tool to help fight child porn, catch cyber  

E-print Network

Researchers develop new search tool to help fight child porn, catch cyber thieves Canada Standard a comment... Post to Facebook 0 0 New #12;Researchers develop new search tool to help fight child porn

Fung, Benjamin C. M.

79

Rethinking the Role of Information Technology-Based Research Tools in Students' Development of Scientific Literacy  

ERIC Educational Resources Information Center

Given the central place IT-based research tools take in scientific research, the marginal role such tools currently play in science curricula is dissatisfying from the perspective of making students scientifically literate. To appropriately frame the role of IT-based research tools in science curricula, we propose a framework that is developed to…

van Eijck, Michiel; Roth, Wolff-Michael

2007-01-01

80

Article A10.4 Introduction to the Research Tools Mind Map  

E-print Network

) Compare resources: Top 30 Web Tools to Search, 100 Useful Tips and Tools to Research the Deep Web (g do their work efficiently. It is assembled as an interactive Web-based mind map, titled Research Adcenter Lab, keyword density analyser, Free Keyword Tool (c) Find research materials: Web of Science

Paris-Sud XI, Université de

81

The Canadian Light Source A new tool for industrial research  

NASA Astrophysics Data System (ADS)

As applied research moves into the 21st century, industry is discovering that traditional analytical techniques are not answering all of their questions. For example, new materials are being developed daily that may have significantly different properties but are chemical indistinguishable using current analysis techniques. It is important for industry to understand these differences and develop those unique properties into a new product. Therefore, today, industry is turning to new tools to shed light on old and new questions. The Canadian Light Source Inc. has assembled an industrial science team and business development office to make synchrotron-based techniques available to pay-for-service clients which range from academia to industry. Since 2000, the industrial science group has conducted approximately 60 projects with a majority coming from the environmental sector with marked increases in the life science sector. In the future, the demand for full client services at synchrotron sources will increase as facilities develop client-friendly access mechanisms.

Cutler, J. N.; Christensen, C.; Kotzer, T. G.; Ogunremi, T.; Pushparajah, T.; Warner, J.

2007-08-01

82

Voice recognition technology as a tool for behavioral research.  

PubMed

Behavioral research often requires the acquisition and processing of large volumes of data. Most current techniques for recording behavior constrain the amount and type of data that can be measured. We developed and tested a system that uses voice recognition technology to collect data on the social interactions and singing patterns of cowbirds (Molothrus ater) living outdoors in a semi-natural environment. We spoke observation data into a wireless microphone that transmitted the data to a computer in the laboratory. After collection, the data were automatically checked for errors and then were entered into a database. Overall, the system performed at extremely high levels of accuracy. Furthermore, owing to the removal of constraints on observers such as breaking visual contact with subjects and manual data entry into a database, we were able to increase the amount of data collected and to collect new measures of social interactions that have not been available to us in the past. We tested the system under the challenging circumstances of field observation, and it performed above our expectations. In a laboratory setting, if transmission difficulties are removed, voice recognition could be even more accurate. We recommend voice recognition as a powerful new tool for the variety of research fields in which measuring behavior is involved. PMID:12060983

White, David J; King, Andrew P; Duncan, Shan D

2002-02-01

83

Direct rapid tooling: a review of current research  

Microsoft Academic Search

Rapid prototyping technologies are now evolving toward rapid tooling. The reasons for this extension are found in the need to further reduce the time-to-market by shortening not only the development phase, but also the industrialization phase of the manufacturing process. The present state of rapid tooling is reviewed and the direct rapid tooling concept, aimed at developing direct and rapid

N. P. Karapatis; J. P. S. van Griethuysen; R. Glardon

1998-01-01

84

RESEARCH ON POLISHING PROCESS OF A SPECIAL POLISHING MACHINE TOOL  

Microsoft Academic Search

In this paper, a serial-parallel hybrid special polishing machine tool based on the elastic polishing theory is developed, which is used for polishing mould surface by using bound abrasives. This machine tool mostly consists of parallel mechanism of three-dimensional moving platform, series rotational mechanism of two degrees of freedom and elastic polishing tool device. The parallel mechanism controls the spatial

Guilian Wang; Yiqiang Wang

2009-01-01

85

IT Tools for Teachers and Scientists, Created by Undergraduate Researchers  

NASA Astrophysics Data System (ADS)

Interns in the Southern California Earthquake Center/Undergraduate Studies in Earthquake Information Technology (SCEC/UseIT) program conduct computer science research for the benefit of earthquake scientists and have created products in growing use within the SCEC education and research communities. SCEC/UseIT comprises some twenty undergraduates who combine their varied talents and academic backgrounds to achieve a Grand Challenge that is formulated around needs of SCEC scientists and educators and that reflects the value SCEC places on the integration of computer science and the geosciences. In meeting the challenge, students learn to work on multidisciplinary teams and to tackle complex problems with no guaranteed solutions. Meantime, their efforts bring fresh perspectives and insight to the professionals with whom they collaborate, and consistently produces innovative, useful tools for research and education. The 2007 Grand Challenge was to design and prototype serious games to communicate important earthquake science concepts. Interns broke themselves into four game teams, the Educational Game, the Training Game, the Mitigation Game and the Decision-Making Game, and created four diverse games with topics from elementary plate tectonics to earthquake risk mitigation, with intended players ranging from elementary students to city planners. The games were designed to be versatile, to accommodate variation in the knowledge base of the player; and extensible, to accommodate future additions. The games are played on a web browser or from within SCEC-VDO (Virtual Display of Objects). SCEC-VDO, also engineered by UseIT interns, is a 4D, interactive, visualization software that enables integration and exploration of datasets and models such as faults, earthquake hypocenters and ruptures, digital elevation models, satellite imagery, global isochrons, and earthquake prediction schemes. SCEC-VDO enables the user to create animated movies during a session, and is now part of a multi-media, general education curriculum at University of Southern California. Throughout this meeting, at the SCEC booth, UseIT interns will be demonstrating both the serious games and SCEC-VDO. SCEC/UseIT is a National Science Foundation Research Experience for Undergraduates site.

Millar, A. Z.; Perry, S.

2007-12-01

86

Science in the Eyes of Preschool Children: Findings from an Innovative Research Tool  

NASA Astrophysics Data System (ADS)

How do young children view science? Do these views reflect cultural stereotypes? When do these views develop? These fundamental questions in the field of science education have rarely been studied with the population of preschool children. One main reason is the lack of an appropriate research instrument that addresses preschool children's developmental competencies. Extensive body of research has pointed at the significance of early childhood experiences in developing positive attitudes and interests toward learning in general and the learning of science in particular. Theoretical and empirical research suggests that stereotypical views of science may be replaced by authentic views following inquiry science experience. However, no preschool science intervention program could be designed without a reliable instrument that provides baseline information about preschool children's current views of science. The current study presents preschool children's views of science as gathered from a pioneering research tool. This tool, in the form of a computer "game," does not require reading, writing, or expressive language skills and is operated by the children. The program engages children in several simple tasks involving picture recognition and yes/no answers in order to reveal their views about science. The study was conducted with 120 preschool children in two phases and found that by the age of 4 years, participants possess an emergent concept of science. Gender and school differences were detected. Findings from this interdisciplinary study will contribute to the fields of early childhood, science education, learning technologies, program evaluation, and early childhood curriculum development.

Dubosarsky, Mia D.

87

Immersive Virtual Environment Technology: A Promising Tool for Future Social and Behavioral Genomics Research and Practice  

Microsoft Academic Search

Social and behavioral research needs to get started now if scientists are to direct genomic discoveries to address pressing public health problems. Advancing social and behavioral science will require innovative and rigorous communication methodologies that move researchers beyond reliance on traditional tools and their inherent limitations. One such emerging research tool is immersive virtual environment technology (virtual reality), a methodology

Susan Persky; Colleen M. McBride

2009-01-01

88

Main topics in transcultural psychiatric research in the Netherlands during the past decade.  

PubMed

The population of the Netherlands has become increasingly diverse in terms of ethnicity and religion, and anti-immigrant attitudes have become more apparent. At the same time, interest in issues linked to transcultural psychiatry has grown steadily. The purpose of this article is to describe the most important results in Dutch transcultural psychiatric research in the last decade and to discuss their relationship with relevant social and political developments in the Netherlands. All relevant PhD theses (N?=?27) between 2000 and 2011 were selected. Screening of Dutch journals in the field of transcultural psychiatry and medical anthropology and a PubMed query yielded additional publications. Forensic and addiction psychiatry were excluded from this review. The results of the review indicate three main topics: (a) the prevalence of psychiatric disorders and their relation to migration issues as social defeat and ethnic density, showing considerable intra- and interethnic differences in predictors and prevalence rates, (b) the social position of refugees and asylum seekers, and its effect on mental health, showing especially high risk among asylum seekers, and (c) the patterns of health-seeking behaviour and use of mental health services, showing a differentiated picture among various migrant groups. Anthropological research brought additional knowledge on all the above topics. The overall conclusion is that transcultural psychiatric research in the Netherlands has made a giant leap since the turn of the century. The results are of international importance and invite redefinition of the relationship between migration and mental health, and reconsideration of its underlying mechanisms in multiethnic societies. PMID:24071745

Laban, Cornelis J; van Dijk, Rob

2013-12-01

89

Towards a Tool for Characterizing the Progression of Academic Research  

E-print Network

The importance of process in successful and effective technology and product development is widely recognized in industry. Tools, such as Technology Readiness Levels (TRLs) and various metrics, have been developed and ...

Leong, Ming

2011-01-01

90

Improving Students' Understanding of Quantum Measurement. II. Development of Research-Based Learning Tools  

ERIC Educational Resources Information Center

We describe the development and implementation of research-based learning tools such as the Quantum Interactive Learning Tutorials and peer-instruction tools to reduce students' common difficulties with issues related to measurement in quantum mechanics. A preliminary evaluation shows that these learning tools are effective in improving students'…

Zhu, Guangtian; Singh, Chandralekha

2012-01-01

91

[Research progress of whole embryo culture tool and its application].  

PubMed

Whole embryo culture (WEC) is an experimental tool, which is made use of embryos in vitro to replace whole animals to investigate the growth and development of early organs, the embryo toxicity of chemical materials and the mechanism of the occurrence of embryo toxicity. Compared with experiment with whole animals, WEC could reduce the number of experimental animals, shorten experimental time, decrease experimental expenses, eliminate disturbing factors and control dosage more exactly. So it is generally received that WEC tool is a good experimental method to match the principles of replacement, reduction, refinement and responsibility. This article is a review of the WEC tool of rat and mouse, including the development of this tool, announcements, and the application in the development of organs, the embryo toxicity of environmental pollution and heavy metal, safety evaluation of medicine and the embryo toxicity of traditional Chinese medicine and its mechanism. There is also a discussion of the application of this tool in the investigation of the embryo toxicity of traditional Chinese medicine. PMID:20506808

Han, Jiayin; Liang, Aihua

2010-03-01

92

Researchers: new resources, tools needed to reduce variation in the admissions decisions.  

PubMed

New research suggests there is considerable variation in the decisions emergency providers make regarding whether to admit patients with certain common, low-mortality conditions. ln some cases, the researchers found that patients were as much as six times more likely to be admitted at some hospitals than others. While available resources and cultural differences likely play a role in this variation, the researchers estimate that reducing this variation in decision making could potentially save as much as $5 billion per year. Data show that EDs are the main source of hospitalizations in this country, and emergency providers make a decision about admission approximately 350,000 times each day, resulting in close to 20 million admissions per year. Researchers found that variation in the admission decision was most prominent for patients presenting with chest pain but no heart attaclk, soft-tissue infections, urinary tract infections, asthma-related difficulties, and COPD. There was little variation in the admission decisions regarding patients with high-risk conditions such as heart attacks, sepsis, or kidney failure. Researchers suggest that reducing this variation in admission decisions will require better tools for determining which patients with lower-mortality conditions likely require hospitalization, and more resources so that physician have good alternatives to hospitalization at their disposal. PMID:25362751

2014-11-01

93

Purdue study finds "label-free" imaging tool tracks nanotubes in cells, blood for biomedical research:  

Cancer.gov

Purdue University researchers have demonstrated a new imaging tool for tracking structures called carbon nanotubes in living cells and the bloodstream, which could aid efforts to perfect their use in biomedical research and clinical medicine.

94

Nearly arc-length tool path generation and tool radius compensation algorithm research in FTS turning  

NASA Astrophysics Data System (ADS)

In the non-rotational symmetrical microstrcture surfaces generation using turning method with Fast Tool Servo(FTS), non-uniform distribution of the interpolation data points will lead to long processing cycle and poor surface quality. To improve this situation, nearly arc-length tool path generation algorithm is proposed, which generates tool tip trajectory points in nearly arc-length instead of the traditional interpolation rule of equal angle and adds tool radius compensation. All the interpolation points are equidistant in radial distribution because of the constant feeding speed in X slider, the high frequency tool radius compensation components are in both X direction and Z direction, which makes X slider difficult to follow the input orders due to its large mass. Newton iterative method is used to calculate the neighboring contour tangent point coordinate value with the interpolation point X position as initial value, in this way, the new Z coordinate value is gotten, and the high frequency motion components in X direction is decomposed into Z direction. Taking a typical microstructure with 4?m PV value for test, which is mixed with two 70?m wave length sine-waves, the max profile error at the angle of fifteen is less than 0.01?m turning by a diamond tool with big radius of 80?m. The sinusoidal grid is machined on a ultra-precision lathe succesfully, the wavelength is 70.2278?m the Ra value is 22.81nm evaluated by data points generated by filtering out the first five harmonics.

Zhao, Minghui; Zhao, Xuesen; Li, Zengqiang; Sun, Tao

2014-08-01

95

N^2 Women is a discipline-specific community for researchers in the communications and networking research fields. The main goal of N^2 Women is to  

E-print Network

N^2 Women is a discipline-specific community for researchers in the communications and networking research fields. The main goal of N^2 Women is to foster connections among women in computer networking and related research fields. N^2 Women allows women to connect with other women who share the same research

Nørvåg, Kjetil

96

"Mythbusters": A Tool for Teaching Research Methods in Psychology  

ERIC Educational Resources Information Center

"Mythbusters" uses multiple research methods to test interesting topics, offering research methods students an entertaining review of course material. To test the effectiveness of "Mythbusters" clips in a psychology research methods course, we systematically selected and showed 4 clips. Students answered questions about the clips, offered their…

Burkley, Edward; Burkley, Melissa

2009-01-01

97

Tools for Monitoring Social Media: A Marketing Research Project  

ERIC Educational Resources Information Center

Knowledge of how to effectively monitor social media is an increasingly valued marketing research skill. This study tests an approach for adding social media content to an undergraduate marketing research class team project. The revised project maintains the expected objectives and parameters of a traditional research project, while integrating…

Veeck, Ann; Hoger, Beth

2014-01-01

98

Specially Made for Science: Researchers Develop Online Tools For Collaborations  

ERIC Educational Resources Information Center

Blogs, wikis, and social-networking sites such as Facebook may get media buzz these days, but for scientists, engineers, and doctors, they are not even on the radar. The most effective tools of the Internet for such people tend to be efforts more narrowly aimed at their needs, such as software that helps geneticists replicate one another's…

Guterman, Lila

2008-01-01

99

Chaos Modeling: Increasing Educational Researchers' Awareness of a New Tool.  

ERIC Educational Resources Information Center

Chaos theory is being used as a tool to study a wide variety of phenomena. It is a philosophical and empirical approach that attempts to explain relationships previously thought to be totally random. Although some relationships are truly random, many data appear to be random but reveal repeatable patterns of behavior under further investigation.…

Bobner, Ronald F.; And Others

100

Sandmark--A Tool for Software Protection Research  

Microsoft Academic Search

Sandmark is a tool that measures the effectiveness of software-based methods for protecting software from piracy, tampering, and reverse engineering. The Sandmark team's goal is to develop techniques that will let users determine empirically which algorithms have the least performance overhead and the highest resilience to attacks.

Christian S. Collberg; Ginger Myles; Andrew Huntwork

2003-01-01

101

A lexical database tool for quantitative phonological research  

Microsoft Academic Search

A lexical database tool tailored for phonological res- earch is described. Database fields include transcrip- tions, glosses and hyperlinks to speech files. Database queries are expressed using HTML forms, and these permit regular expression search on any combination of fields. Regular expressions are passed directly to a Perl CGI program, enabling the full flexibility of Perl extended regular expressions. The

Steven Bird

1997-01-01

102

A critical appraisal tool for library and information research  

Microsoft Academic Search

Purpose – As the interest in evidence-based librarianship increases, so does the need for a standardized practice methodology. One of the most essential components of EBL, critical appraisal, has not been fully established within the library literature. The purpose of this paper is to outline and describe a thorough critical appraisal tool and process that can be applied to library

Lindsay Glynn

2006-01-01

103

Tools  

NSDL National Science Digital Library

The goal of the lesson is not for students to learn what the simple machines are, even though this is an underlying theme. Students will approach the lesson in a much more open-minded fashion. They will discuss tools and how they function. This will naturally lead to acknowledgment of how tools make our lives easier. By categorizing everyday items, students will come to understand the natural functions of tools. This base of knowledge will lead into exercises and discussions about how complex machines are a conglomerate of simpler tools and motions, as well as how tools have changed and become more sophisticated throughout history. At the end of the lesson to reemphasize the importance of tools in human society, students will write a paper in which they imagine a world without a particular tool.

Science Netlinks;

2005-06-13

104

Research investigation of helicopter main rotor/tail rotor interaction noise  

NASA Technical Reports Server (NTRS)

Acoustic measurements were obtained in a Langley 14 x 22 foot Subsonic Wind Tunnel to study the aeroacoustic interaction of 1/5th scale main rotor, tail rotor, and fuselage models. An extensive aeroacoustic data base was acquired for main rotor, tail rotor, fuselage aerodynamic interaction for moderate forward speed flight conditions. The details of the rotor models, experimental design and procedure, aerodynamic and acoustic data acquisition and reduction are presented. The model was initially operated in trim for selected fuselage angle of attack, main rotor tip-path-plane angle, and main rotor thrust combinations. The effects of repositioning the tail rotor in the main rotor wake and the corresponding tail rotor countertorque requirements were determined. Each rotor was subsequently tested in isolation at the thrust and angle of attack combinations for trim. The acoustic data indicated that the noise was primarily dominated by the main rotor, especially for moderate speed main rotor blade-vortex interaction conditions. The tail rotor noise increased when the main rotor was removed indicating that tail rotor inflow was improved with the main rotor present.

Fitzgerald, J.; Kohlhepp, F.

1988-01-01

105

Research investigation of helicopter main rotor\\/tail rotor interaction noise  

Microsoft Academic Search

Acoustic measurements were obtained in a Langley 14 x 22 foot Subsonic Wind Tunnel to study the aeroacoustic interaction of 1\\/5th scale main rotor, tail rotor, and fuselage models. An extensive aeroacoustic data base was acquired for main rotor, tail rotor, fuselage aerodynamic interaction for moderate forward speed flight conditions. The details of the rotor models, experimental design and procedure,

J. Fitzgerald; F. Kohlhepp

1988-01-01

106

Object-oriented simulation research on components of inner fuel main pipe in aero-engine  

Microsoft Academic Search

In order to find the control characteristics of fuel flow rate of inner fuel main pipe in aero-engines, the influences of parameters on the flow rate need to be studied systematically. This paper uses object-oriented AMESim to investigate modelling and simulation of the main control components. Modeling methods of components such as electrohydraulic servo valve, pressure difference valve and flow

Wang Bin; Zhou Lifeng; Yang Jinli; Ye Zhifeng

2010-01-01

107

The Stuttering Treatment Research Evaluation and Assessment Tool (STREAT): Evaluating Treatment Research as Part of Evidence-Based Practice  

ERIC Educational Resources Information Center

Purpose: This article presents, and explains the issues behind, the Stuttering Treatment Research Evaluation and Assessment Tool (STREAT), an instrument created to assist clinicians, researchers, students, and other readers in the process of critically appraising reports of stuttering treatment research. Method: The STREAT was developed by…

Davidow, Jason H.; Bothe, Anne K.; Bramlett, Robin E.

2006-01-01

108

Research SummaryForest Research Engaging with rivers: using imaginative and creative approaches as a learning tool  

E-print Network

Research SummaryForest Research Engaging with rivers: using imaginative and creative approaches communities. In the RIVERS project we tested the use of creative writing as a tool to engage with river but systematic review of research evidence on innovative approaches to participatory river basin planning m

109

The nanosatellite Munin, a simple tool for auroral research  

NASA Astrophysics Data System (ADS)

The scientific objective of the nanosatellite Munin is to collect data of the auroral activity over both the northern and southern poles. The satellite has been developed by Swedish Institute of Space Physics under international cooperation. The purpose of the Munin project is both to achieve the scientific objectives and to show that it is possible to achieve such objectives by a very small satellite. A passive magnetic attitude control system is used to stabilize Munin along the direction of an intensity vector of the local geomagnetic field. The paper presents the development of the attitude control system and gives a brief discription of the tools and algorithms used for the attitude determination.

Barabash, S.; Kiryushkin, I.; Norberg, O.; Ovchinnikov, M.; Penkov, V.

110

Main trends in experimental morphological research in angiology and outlook for its development  

NASA Technical Reports Server (NTRS)

The main prospective trends in the problem of collateral circulation and new trends in experimental angiology with respect to the effect of gravitational forces, hypodynamia and hypokinesia on the vascular bed are discussed.

Dzhavakhishvili, N. A.; Melman, Y. P.

1980-01-01

111

Nonlinear active disturbance rejection controller research of main engine for ship  

Microsoft Academic Search

Applying mathematics model of nonlinear ship main engine control and the wave disturbances to the design of electronic governor, and considering the uncertainty of model parameters and the characteristics of servo-system makes the model have the unmatched uncertainty correspondingly. In order to solve the difficulty,an active disturbance rejection nonlinear control strategy is proposed,and a ship main engine ADRC controller is

Weigang Pan; Hairong Xiao; Yaozhen Han; Changshun Wang; Guiyong Yang

2010-01-01

112

Research on a new type of ship main engine remote control simulation system  

Microsoft Academic Search

Taking the main engine and propulsion system of the large-scale container ships as the controlled object, a type of main engine remote control simulation system is designed, using the CAN-bus and database administration technology as well as touch-screen equipments. The system is composed of ECR controls system, BCR control system, and local control system with high density of integration. It

Yang Yang; Chen Guo; Zhi-peng Shen; Jian-bo Sun

2010-01-01

113

Education of research ethics for clinical investigators with Moodle tool  

PubMed Central

Background In clinical research scientific, legal as well as ethical aspects are important. It is well known that clinical investigators at university hospitals have to undertake their PhD-studies alongside their daily work and reconciling work and study can be challenging. The aim of this project was to create a web based course in clinical research bioethics (5 credits) and to examine whether the method is suitable for teaching bioethics. The course comprised of six modules: an initial examination (to assess knowledge in bioethics), information on research legislation, obtaining permissions from authorities, writing an essay on research ethics, preparing one’s own study protocol, and a final exam. All assignments were designed with an idea of supporting students to reflect on their learning with their own research. Methods 57 PhD-students (medical, nursing and dental sciences) enrolled and 46 completed the course. Course evaluation was done using a questionnaire. The response rate was 78%. Data were analyzed using quantitative methods and qualitative content analysis. Results The course was viewed as useful and technically easy to perform. Students were pleased with the guidance offered. Personal feedback from teachers about students’ own performance was seen advantageous and helped them to appreciate how these aspects could be applied their own studies. The course was also considered valuable for future research projects. Conclusions Ethical issues and legislation of clinical research can be understood more easily when students can reflect the principles upon their own research project. Web based teaching environment is a feasible learning method for clinical investigators. PMID:24330709

2013-01-01

114

IT Tools for Teachers and Scientists, Created by Undergraduate Researchers  

Microsoft Academic Search

Interns in the Southern California Earthquake Center\\/Undergraduate Studies in Earthquake Information Technology (SCEC\\/UseIT) program conduct computer science research for the benefit of earthquake scientists and have created products in growing use within the SCEC education and research communities. SCEC\\/UseIT comprises some twenty undergraduates who combine their varied talents and academic backgrounds to achieve a Grand Challenge that is formulated around

A. Z. Millar; S. Perry

2007-01-01

115

The airborne infrared scanner as a geophysical research tool  

USGS Publications Warehouse

The infrared scanner is proving to be an effective anomaly-mapping tool, albeit one which depicts surface emission directly and heat mass transfer from depths only indirectly and at a threshold level 50 to 100 times the normal conductive heat flow of the earth. Moreover, successive terrain observations are affected by time-dependent variables such as the diurnal and seasonal warming and cooling cycle of a point on the earth's surface. In planning precise air borne surveys of radiant flux from the earth's surface, account must be taken of background noise created by variations in micrometeorological factors and emissivity of surface materials, as well as the diurnal temperature cycle. The effect of the diurnal cycle may be minimized by planning predawn aerial surveys. In fact, the diurnal change is very small for most water bodies and the emissivity factor for water (e) =~ 1 so a minimum background noise is characteristic of scanner records of calm water surfaces.

Friedman, Jules D.

1970-01-01

116

The NASA Exoplanet Archive: Data and Tools for Exoplanet Research  

NASA Astrophysics Data System (ADS)

We describe the contents and functionality of the NASA Exoplanet Archive, a database and toolset funded by NASA to support astronomers in the exoplanet community. The current content of the database includes interactive tables containing properties of all published exoplanets, Kepler planet candidates, threshold-crossing events, data validation reports and target stellar parameters, light curves from the Kepler and CoRoT missions and from several ground-based surveys, and spectra and radial velocity measurements from the literature. Tools provided to work with these data include a transit ephemeris predictor, both for single planets and for observing locations, light curve viewing and normalization utilities, and a periodogram and phased light curve service. The archive can be accessed at http://exoplanetarchive.ipac.caltech.edu.

Akeson, R. L.; Chen, X.; Ciardi, D.; Crane, M.; Good, J.; Harbut, M.; Jackson, E.; Kane, S. R.; Laity, A. C.; Leifer, S.; Lynn, M.; McElroy, D. L.; Papin, M.; Plavchan, P.; Ramírez, S. V.; Rey, R.; von Braun, K.; Wittman, M.; Abajian, M.; Ali, B.; Beichman, C.; Beekley, A.; Berriman, G. B.; Berukoff, S.; Bryden, G.; Chan, B.; Groom, S.; Lau, C.; Payne, A. N.; Regelson, M.; Saucedo, M.; Schmitz, M.; Stauffer, J.; Wyatt, P.; Zhang, A.

2013-08-01

117

A validated set of tool pictures with matched objects and non-objects for laterality research.  

PubMed

Neuropsychological and neuroimaging research has established that knowledge related to tool use and tool recognition is lateralized to the left cerebral hemisphere. Recently, behavioural studies with the visual half-field technique have confirmed the lateralization. A limitation of this research was that different sets of stimuli had to be used for the comparison of tools to other objects and objects to non-objects. Therefore, we developed a new set of stimuli containing matched triplets of tools, other objects and non-objects. With the new stimulus set, we successfully replicated the findings of no visual field advantage for objects in an object recognition task combined with a significant right visual field advantage for tools in a tool recognition task. The set of stimuli is available as supplemental data to this article. PMID:24821308

Verma, Ark; Brysbaert, Marc

2015-01-01

118

Neuropsychiatric Genetics Research Group The main aim of the Neuropsychiatric Genetics Research Group (NGRG) is to study the  

E-print Network

available a sample of 2000 parent-child trios collected throughout the sites involved in the AGP. The main of interaction between risk genes, demonstration of the involvement of synaptic trafficking mechanisms and cell

O'Mahony, Donal E.

119

Reimagining Science Education and Pedagogical Tools: Blending Research with Teaching  

ERIC Educational Resources Information Center

The future of higher education in the sciences will be marked by programs that link skilled educators and research scientists from around the world with teachers for professional development and with students for high-impact learning--either virtually or physically in the field. These programs will use technology where possible to build new and…

McLaughlin, Jacqueline S.

2010-01-01

120

RESEARCH Open Access Do simple screening statistical tools help to  

E-print Network

: As a result of reporting bias, or frauds, false or misunderstood findings may represent the majority of published research claims. This article provides simple methods that might help to appraise the quality- dence, the question of how evidence-based the published results should be appraised and translated

Paris-Sud XI, Université de

121

TPACK: An Emerging Research and Development Tool for Teacher Educators  

ERIC Educational Resources Information Center

TPACK (technological pedagogical content knowledge) has emerged as a clear and useful construct for researchers working to understand technology integration in learning and teaching. Whereas first generation TPACK work focused upon explaining and interpreting the construct, TPACK has now entered a second generation where the focus is upon using…

Baran, Evrim; Chuang, Hsueh-Hua; Thompson, Ann

2011-01-01

122

The Portable Usability Testing Lab: A Flexible Research Tool.  

ERIC Educational Resources Information Center

A group of faculty at the University of Georgia obtained funding for a research and development facility called the Learning and Performance Support Laboratory (LPSL). One of the LPSL's primary needs was obtaining a portable usability lab for software testing, so the facility obtained the "Luggage Lab 2000." The lab is transportable to any site…

Hale, Michael E.; And Others

123

Online Tools Allow Distant Students to Collaborate on Research Projects  

ERIC Educational Resources Information Center

The Wesleyan Academy and Moravian School in St. Thomas, Virgin Islands, recently joined forces with Evergreen Elementary in Fort Lewis, Wash., to collaborate on a research project using My eCoach Online (http://myecoach.com) as the primary medium to share information, post ideas and findings, and develop inquiry projects on 10 topics about water.…

T.H.E. Journal, 2005

2005-01-01

124

Main differences in Body Image (BI) perception between American and Chinese consumers: selected research results  

Microsoft Academic Search

In recent years, there has been an observably increasing interest in one's own body appearance. By attempting to identify the main differences in body image perception within two culturally different backgrounds (the US and China), this paper examines the relationship between the way consumers perceive (ideal) body image in a particular culture, and the product categories advertised in media helping

Dagmar Skokanová

2010-01-01

125

Conceptualising the Use of Facebook in Ethnographic Research: As Tool, as Data and as Context  

ERIC Educational Resources Information Center

This article proposes a three-part conceptualisation of the use of Facebook in ethnographic research: as a tool, as data and as context. Longitudinal research with young adults at a time of significant change provides many challenges for the ethnographic researcher, such as maintaining channels of communication and high rates of participant…

Baker, Sally

2013-01-01

126

Antarctic Committee Reports, No. 17, Main Results of Twenty Years' Research in the Antarctic.  

National Technical Information Service (NTIS)

This collection contains reports presented at the Second All-Union Conference on the Study of the Antarctic, on the occasion of the twentieth anniversary of Soviet research on the sixth continent and fruitful international scientific cooperation in this r...

G. A. Avsyuk

1984-01-01

127

’No Problem Here’: action research against racism in a mainly white area  

Microsoft Academic Search

The paper outlines the result of a one?year project of action research into the prevalence and nature of racism in two primary schools and the implementation of multi?cultural and anti?racist guidelines in Scotland. Two schools are examined with respect to these factors by teachers. The conclusion is that the action research, although not officially supported by funding, except for a

Patricia Donald; Susan Gosling; Jean Hamilton; Nicolas Hawkes; David McKenzie; Ian Stronach

1995-01-01

128

2011 Raditation & Climate Gordon Research Conference (July 10-15 2011- Colby College, Waterville, Maine)  

Microsoft Academic Search

The 2011 Gordon Research Conference on Radiation and Climate will present cutting-edge research on outstanding issues in climate change, particularly those in which the interactions between clouds, aerosols, and precipitation play a major role. The Conference will feature a broad range of topics, including grand challenges in atmospheric radiation and climate, cloud and water vapor feedbacks, aerosol-cloud-precipitation-climate interactions across scales,

Max Hoggblom

2012-01-01

129

Research and Evaluation Trends in the Uses of Computer-Based Tools for Learning and Teaching.  

ERIC Educational Resources Information Center

Current research and evaluation studies describe changing knowledge about the effects and conditions of computer-based tools in learning and teaching in elementary and secondary school classrooms. Current studies of computer-based tool use are characterized by: (1) a focus on many dimensions of learning, learners, and learning environments; (2) an…

Hunter, Beverly

130

Pre-service primary teachers' understanding of electricity - Using concept mapping as a research tool  

Microsoft Academic Search

Concept mapping has been used variously as a tool for learning and teaching science, for encouraging reflective learning, for assessing students' con- ceptual development and as a research tool, probing understanding and searching for alternative frameworks and misconceptions. In the study described in this paper, concept mapping was one of a number of probes used to explore the conceptual understanding

Bruce Murray; Rae Stark

131

Research Summary Sustainability impact assessment: tools for environmental, social and economic  

E-print Network

Research Summary Sustainability impact assessment: tools for environmental, social and economic to produce Sustainability Impact Assessment Tools (SIATs) that will be used to predict the impacts of sustainability issues in European regions, and has developed a `Framework for Participatory Impact Assessment

132

An Evaluation Tool for Machine Translation: Fast Evaluation for MT Research  

Microsoft Academic Search

In this paper we present a tool for the evaluation of translat ion quality. First, the typical requirements of such a tool i n the framework of machine translation (MT) research are discussed. We define e valuation criteria which are more adequate than pure edit distance and we describe how the measurement along these quality criteria is performed semi-automaticallyin a

Gregor Leusch; Hermann Ney; RWTH Aachen

2000-01-01

133

CAMS as a tool for human factors research in spaceflight  

NASA Astrophysics Data System (ADS)

The paper reviews a number of research studies that were carried out with a PC-based task environment called Cabin Air Management System (CAMS) simulating the operation of a spacecraft's life support system. As CAMS was a multiple task environment, it allowed the measurement of performance at different levels. Four task components of different priority were embedded in the task environment: diagnosis and repair of system faults, maintaining atmospheric parameters in a safe state, acknowledgement of system alarms (reaction time), and keeping a record of critical system resources (prospective memory). Furthermore, the task environment permitted the examination of different task management strategies and changes in crew member state (fatigue, anxiety, mental effort). A major goal of the research programme was to examine how crew members adapted to various forms of sub-optimal working conditions, such as isolation and confinement, sleep deprivation and noise. None of the studies provided evidence for decrements in primary task performance. However, the results showed a number of adaptive responses of crew members to adjust to the different sub-optimal working conditions. There was evidence for adjustments in information sampling strategies (usually reductions in sampling frequency) as a result of unfavourable working conditions. The results also showed selected decrements in secondary task performance. Prospective memory seemed to be somewhat more vulnerable to sub-optimal working conditions than performance on the reaction time task. Finally, suggestions are made for future research with the CAMS environment.

Sauer, Juergen

2004-01-01

134

Neuroproteomics as a promising tool in Parkinson's disease research  

PubMed Central

Despite the vast number of studies on Parkinson’s disease (PD), its effective diagnosis and treatment remains unsatisfactory. Hence, the relentless search for an optimal cure continues. The emergence of neuroproteomics, with its sophisticated techniques and non-biased ability to quantify proteins, provides a methodology with which to study the changes in neurons that are associated with neurodegeneration. Neuroproteomics is an emerging tool to establish disease-associated protein profiles, while also generating a greater understanding as to how these proteins interact and undergo post-translational modifications. Furthermore, due to the advances made in bioinformatics, insight is created concerning their functional characteristics. In this review, we first summarize the most prominent proteomics techniques and then discuss the major advances in the fast-growing field of neuroproteomics in PD. Ultimately, it is hoped that the application of this technology will lead towards a presymptomatic diagnosis of PD, and the identification of risk factors and new therapeutic targets at which pharmacological intervention can be aimed. PMID:18523721

Daniels, William M. U.; Gotz, Jurgen

2010-01-01

135

NASA Global Hawk: A New Tool for Earth Science Research  

NASA Technical Reports Server (NTRS)

This slide presentation reviews the Global Hawk, a unmanned aerial vehicle (UAV) that NASA plans to use for Earth Sciences research. The Global Hawk is the world's first fully autonomous high-altitude, long-endurance aircraft, and is capable of conducting long duration missions. Plans are being made for the use of the aircraft on missions in the Arctic, Pacific and Western Atlantic Oceans. There are slides showing the Global Hawk Operations Center (GHOC), Flight Control and Air Traffic Control Communications Architecture, and Payload Integration and Accommodations on the Global Hawk. The first science campaign, planned for a study of the Pacific Ocean, is reviewed.

Hall, Phill

2009-01-01

136

Examinations of redundancy in audio messages and programmed texts as research tools  

E-print Network

EXAMINATIONS OF REDUNDANCY IN AUDIO MESSAGES AND PROGRAMMED TEXTS AS RESEARCH TOOLS A Thesis by CAROL ANN CONWAY ADAMS Submitted to the Graduate College of Texas A&M University in partial fulfillment of the requirement for the degree... of MASTER OF SCIENCE December 197B Major Subject: Industrial Engineering EXAMINATIONS OF REDUNDANCY IN AUDIO MESSAGES AND PROGRAMMED TEXTS AS RESEARCH TOOLS A Thesis by CAROL ANN CONWAY ADAMS Approved as to style and content by: (Chairman of C ittee...

Adams, Carol Ann Conway

2012-06-07

137

HILAS Flight Operations Research: Development of Risk\\/Safety Management, Process Improvement and Task Support Tools  

Microsoft Academic Search

This paper reports on flight operations research, conducted as part of the work requirements for the Flight Operations Strand\\u000a of the Human Integration into the Lifecycle of Aviation Systems (HILAS) project. Specifically, it presents a provisional framework\\u000a for a suite of integrated Flight Operations tools developed in this research. It is anticipated that these tools will be used\\u000a by different

Joan Cahill; Nick Mc Donald; Pernilla Ulfvengren; Franklyn Young; Yeray Ramos; Gabriel Losa

2007-01-01

138

The NASA Human Research Wiki - An Online Collaboration Tool  

NASA Technical Reports Server (NTRS)

The Exploration Medical Capability (ExMC) element is one of six elements of the Human Research Program (HRP). ExMC is charged with decreasing the risk of: "Inability to adequately recognize or treat an ill or injured crew member" for exploration-class missions In preparation for exploration-class missions, ExMC has compiled a large evidence base, previously available only to persons within the NASA community. ExMC has developed the "NASA Human Research Wiki" in an effort to make the ExMC information available to the general public and increase collaboration within and outside of NASA. The ExMC evidence base is comprised of several types of data, including: (1)Information on more than 80 medical conditions which could occur during space flight (a)Derived from several sources (b)Including data on incidence and potential outcomes, as captured in the Integrated Medical Model s (IMM) Clinical Finding Forms (CliFFs). (2)Approximately 25 gap reports (a)Identify any "gaps" in knowledge and/or technology that would need to be addressed in order to provide adequate medical support for these novel missions.

Barr, Yael; Rasbury, Jack; Johnson, Jordan; Barstend, Kristina; Saile, Lynn; Watkins, Sharmi

2012-01-01

139

CDPP tools : Promoting research and education with AMDA, 3DView and the propagation tool in space physics  

NASA Astrophysics Data System (ADS)

The CDPP (Centre de Données de la Physique des Plasmas, http://cdpp.eu/), the French data center for plasma physics, is engaged for more than a decade in the archiving and dissemination of plasma data products from space missions and ground observatories. Besides these activities, the CDPP developed an online analysis tool, AMDA (http://amda.cdpp.eu/). It enables in depth analysis of large amount of space physics, planetary and model data through dedicated functionalities such as: visualization, data mining, cataloguing ... It is used (about 250 connections per month) by scientists for their own research, but also by graduate students in the classroom and for dedicated projects. AMDA is ideally complemented by two companion tools also developed at CDPP : 3DView (http://3dview.cdpp.eu/) which provides immersive data visualisations in planetary environments and the Propagation Tool (http://propagationtool.cdpp.eu/) which enables tracking of solar perturbations in the heliosphere with different analytical models and white light imaging techniques. This presentation will focus on some scientific cases combining the use of the three tools. (2.1) Data Mining and Intelligent Systems for Massive Data Sets

Genot, Vincent; Cecconi, Baptiste

140

Main Findings and Policy Implications from the Research Project Public Perceptions of Mountain Forests in Switzerland  

Microsoft Academic Search

The research project was carried out in order to obtain more knowledge of the attitudes of people living in the mountain areas of Switzerland towards forests, forestry and forest politics. A questionnaire was sent to 2160 private individuals and 72 communal councillors responsible for the forest in their own communes. It contained both questions which the respondents were asked to

Zimmermann Willi; Wild-Eck Stephan

141

Component biomass equations for black spruce in Maine. Forest Service research paper (Final)  

SciTech Connect

Component biomass prediction equations are presented for young black spruce (Picea mariana B.S.P. (Mill.)) in northern Maine. A weighted least-squares model was used to construct the equations for small trees from 1 to 15 cm d.b.h., and an ordinary least-squares model for trees less than 2 m in height. A linearized allometric model was also tested but was not used. Equations were developed for over-dry needle, branch, bolewood, bolebark, above-ground, root, and complete tree biomass components.

Czapowskyj, M.M.; Robison, D.J.; Briggs, R.D.; White, E.H.

1985-01-01

142

Community Coordinated Modeling Center (CCMC): Providing Access to Space Weather Models and Research Support Tools  

NASA Astrophysics Data System (ADS)

The Community Coordinated Modeling Center at NASA, Goddard Space flight Center, provides access to state-of-the-art space weather models to the research community. The majority of the models residing at the CCMC are comprehensive computationally intensive physics-based models. The CCMC also provides free services and tools to assist the research community in analyzing the results from the space weather model simulations. We present an overview of the available tools and services at the CCMC: the Runs-On-Request system, the online visualization, the Kameleon access and interpolation library and the Metrics Challenge tools suite.

Chulaki, A.; Bakshi, S. S.; Berrios, D.; Hesse, M.; Kuznetsova, M. M.; Lee, H.; MacNeice, P. J.; Mendoza, A. M.; Mullinix, R.; Patel, K. D.; Pulkkinen, A.; Rastaetter, L.; Shim, J.; Taktakishvili, A.; Zheng, Y.

2011-12-01

143

Research policy and review 11. New tools for a planner's toolkit  

Microsoft Academic Search

After a flirtation with pure science and the liberal arts, professional education in all fields is once again tool-and-craft oriented. Still, the main tools come from high-status science and humanities. But the sciences now advocate design, holism, purpose, choice, emergentism, anima, history, and discontinuity; whereas the humanities stress ambiguity, incommensurability, impurity, and perversion. What is in prospect is a richer,

M H Krieger

1986-01-01

144

Research Report 2010 The main research of the Department of Training and Movement Sciences of the Humboldt-  

E-print Network

international sports science research. In addition to the skills in training science, biomechanics and motor and movement sciences as well as in sports medicine in 1995 and got his habiliation in biomechanics in 2002 control and safety of locomotion. Through an integrative approach of biomechanics, physiology

Röder, Beate

145

Composition and emissions of VOCs in main- and side-stream smoke of research cigarettes  

NASA Astrophysics Data System (ADS)

It is well known that mainstream (MS) and sidestream (SS) cigarette smoke contains a vast number of chemical substances. Previous studies have emphasized SS smoke rather than MS smoke to which smokers are exposed, and most have used chamber tests that have several disadvantages such as wall losses. Emissions from standard research cigarettes have been measured, but relatively few constituents have been reported, and only the 1R4F (low nicotine) cigarette type has been tested. This study provides a comprehensive characterization of total, MS and SS smoke emissions for the 1R5F (ultra low nicotine), 2R4F (low nicotine), and 1R3F (standard nicotine) research cigarettes research cigarettes, including emission factors for a number of toxic compounds (e.g., benzene) and tobacco smoke tracers (e.g., 2,5-dimethyl furan). Emissions of volatile organic compounds (VOCs) and particulate matter (PM) are quantified using a dynamic dilution emission measurement system that is shown to produce accurate, rapid and reproducible results for over 30 VOCs and PM. SS and MS emissions were accurately apportioned based on a mass balance of total emissions. As expected, SS emissions greatly exceeded MS emissions. The ultra low nicotine cigarette had lower emissions of most VOCs compared to low and standard nicotine cigarettes, which had similar emissions. Across the three types of cigarettes, emissions of benzene (296-535 ?g cig -1), toluene (541-1003 ?g cig -1), styrene (90-162 ?g cig -1), 2-dimethyl furan (71-244 ?g cig -1), naphthalene (15-18 ?g cig -1) and other VOCs were generally comparable to or somewhat higher than literature estimates using chamber tests.

Charles, Simone M.; Batterman, S. A.; Jia, Chunrong

146

Main differences between volatiles of sparkling and base wines accessed through comprehensive two dimensional gas chromatography with time-of-flight mass spectrometric detection and chemometric tools.  

PubMed

The main changes in the volatile profile of base wines and their corresponding sparkling wines produced by traditional method were evaluated and investigated for the first time using headspace solid-phase microextraction combined with comprehensive two-dimensional gas chromatography with time-of-flight mass spectrometry detection (GC×GC/TOFMS) and chemometric tools. Fisher ratios helped to find the 119 analytes that were responsible for the main differences between base and sparkling wines and principal component analysis explained 93.1% of the total variance related to the selected 78 compounds. It was also possible to observe five subclusters in base wines and four subclusters in sparkling wines samples through hierarchical cluster analysis, which seemed to have an organised distribution according to the regions where the wines came from. Twenty of the most important volatile compounds co-eluted with other components and separation of some of them was possible due to GC×GC/TOFMS performance. PMID:24996354

Welke, Juliane Elisa; Zanus, Mauro; Lazzarotto, Marcelo; Pulgati, Fernando Hepp; Zini, Cláudia Alcaraz

2014-12-01

147

New Tools for New Literacies Research: An Exploration of Usability Testing Software  

ERIC Educational Resources Information Center

Competency in the new literacies of the Internet is essential for participating in contemporary society. Researchers studying these new literacies are recognizing the limitations of traditional methodological tools and adapting new technologies and new media for use in research. This paper reports our exploration of usability testing software to…

Asselin, Marlene; Moayeri, Maryam

2010-01-01

148

Random Table and Its Ground Truth Automatic Generation: A Tool for Table Understanding Research  

E-print Network

Random Table and Its Ground Truth Automatic Generation: A Tool for Table Understanding Research- ing research. It can analyze any given table ground truth and generate documents that include similar matching ground truthing idea, the table ground truth data for the generated table elements become

Wang, Yalin

149

Cephalopod culture: current status of main biological models and research priorities.  

PubMed

A recent revival in using cephalopods as experimental animals has rekindled interest in their biology and life cycles, information with direct applications also in the rapidly growing ornamental aquarium species trade and in commercial aquaculture production for human consumption. Cephalopods have high rates of growth and food conversion, which for aquaculture translates into short culture cycles, high ratios of production to biomass and high cost-effectiveness. However, at present, only small-scale culture is possible and only for a few species: the cuttlefish Sepia officinalis, the loliginid squid Sepioteuthis lessoniana and the octopuses Octopus maya and O. vulgaris. These four species are the focus of this chapter, the aims of which are as follows: (1) to provide an overview of the culture requirements of cephalopods, (2) to highlight the physical and nutritional requirements at each phase of the life cycle regarded as essential for successful full-scale culture and (3) to identify current limitations and the topics on which further research is required. Knowledge of cephalopod culture methods is advanced, but commercialization is still constrained by the highly selective feeding habits of cephalopods and their requirement for large quantities of high-quality (preferably live) feed, particularly in the early stages of development. Future research should focus on problems related to the consistent production of viable numbers of juveniles, the resolution of which requires a better understanding of nutrition at all phases of the life cycle and better broodstock management, particularly regarding developments in genetic selection, control of reproduction and quality of eggs and offspring. PMID:24880794

Vidal, Erica A G; Villanueva, Roger; Andrade, José P; Gleadall, Ian G; Iglesias, José; Koueta, Noussithé; Rosas, Carlos; Segawa, Susumu; Grasse, Bret; Franco-Santos, Rita M; Albertin, Caroline B; Caamal-Monsreal, Claudia; Chimal, Maria E; Edsinger-Gonzales, Eric; Gallardo, Pedro; Le Pabic, Charles; Pascual, Cristina; Roumbedakis, Katina; Wood, James

2014-01-01

150

[The main directions of research on the causes conditioning the occurrence of the borderline personality disorders].  

PubMed

Currently, there are two main directions of explaining the occurrence of the borderline personality disorders (BPD). The first of them attempts to explain them upon the constitutional basis, finding the causes in the genetic conditioning, biological and organic factors. The other one underline a role of the psychological developmental categories. A significant role is ascribed to traumatic childhood mental experiences such as: harassment and sexual abuse, as well as neglect of emotional and developmental needs of a child. About 40-71% of the infirm with the borderline personality admits to have been sexually abused. It was observed that there is a connection between the extent of sexual abuse of an individual in childhood and the intensification of the disorders proper for the borderline personality. One should, however, point out that sexual abuse, although they are regarded as a risk factor, are not seen as specific to the infirm with the borderline personality disorders. Moreover, there is a third direction referred to in the literature, seeking the causes of the occurrence of the borderline personality in a significant influence of social-cultural and environment factors. It was noticed that there is a significant correlation between the social situation and the degree of dissemination of those disorders. The borderline personality disorders are more frequent among the people of the low social status background and with relatively low level of education. More and more frequently, theorists and clinical personnel adhere to the view that the development of that disorder is caused by a combination of neurobiological and social factors, together with the pathological qualities of early-childhood development. PMID:22097186

Og?odek, Ewa; Araszkiewicz, Aleksander

2011-10-01

151

Development of Advanced Computational Aeroelasticity Tools at NASA Langley Research Center  

NASA Technical Reports Server (NTRS)

NASA Langley Research Center has continued to develop its long standing computational tools to address new challenges in aircraft and launch vehicle design. This paper discusses the application and development of those computational aeroelastic tools. Four topic areas will be discussed: 1) Modeling structural and flow field nonlinearities; 2) Integrated and modular approaches to nonlinear multidisciplinary analysis; 3) Simulating flight dynamics of flexible vehicles; and 4) Applications that support both aeronautics and space exploration.

Bartels, R. E.

2008-01-01

152

An agenda for research in the managerial evaluation of computer-aided software engineering (CASE) tool impacts  

Microsoft Academic Search

It is suggested that the complete lack of validated research demonstrating productivity benefits of computer-aided software engineering (CASE) tools is due to a number of inherent difficulties in the CASE evaluation process. A research agenda is set forth to address the shortfalls in managers' current ability to evaluate these tools. Managerial impacts that are commonly associated with CASE tools are

Chris F. Kemerer

1989-01-01

153

Isotope pattern deconvolution as rising tool for isotope tracer studies in environmental research  

NASA Astrophysics Data System (ADS)

During the last decade stable isotope tracers have emerged as versatile tool in ecological research. Besides 'intrinsic' isotope tracers caused by the natural variation of isotopes, the intentional introduction of 'extrinsic' enriched stable isotope tracers into biological systems has gained significant interest. Hereby the induced change in the natural isotopic composition of an element allows amongst others for studying the fate and fluxes of metals, trace elements and species in organisms or provides an intrinsic marker or tag of particular biological samples. Due to the shoreless potential of this methodology, the number of publications dealing with applications of isotope (double) spikes as tracers to address research questions in 'real world systems' is constantly increasing. However, some isotope systems like the natural Sr isotopic system, although potentially very powerful for this type of application, are still rarely used, mainly because their adequate measurement/determination poses major analytical challenges; as e.g. Sr is available in significant amounts in natural samples. In addition, biological systems underlie complex processes such as metabolism, adsorption/desorption or oxidation/reduction. As a consequence, classic evaluation approaches such as the isotope dilution mass spectrometry equation are often not applicable because of the unknown amount of tracer finally present in the sample. Isotope pattern deconvolution (IPD), based on multiple linear regression, serves as simplified alternative data processing strategy to double spike isotope dilution calculations. The outstanding advantage of this mathematical tool lies in the possibility of deconvolving the isotope pattern in a spiked sample without knowing the quantities of enriched isotope tracer being incorporated into the natural sample matrix as well as the degree of impurities and species-interconversion (e.g. from sample preparation). Here, the potential of IPD for environmental tracer studies is critically discussed, where special emphasis is set on evaluating different data processing strategies on the example of enriched stable Sr isotopes.1 The analytical key parameters such as blank (Kr, Sr and Rb), variation of the natural Sr isotopic composition in the sample, mass bias, interferences (Rb) and total combined uncertainty are considered. A full metrological protocol for data processing using IPD is presented based on data gained during two transgenerational marking studies of fish, where the transfer of a Sr isotope double spike (84Sr and 86Sr) from female spawners of common carp (Cyprinus carpio L.) and brown trout (Salmo trutta f.f.)2 to the centre of the otoliths of their offspring was studied by (LA)-MC-ICP-MS. 1J. Irrgeher, A. Zitek, M. Cervicek and T. Prohaska, J. Anal. At. Spectrom., 2014, 29, 193-200. 2A. Zitek, J. Irrgeher, M. Kletzl, T. Weismann and T. Prohaska, Fish. Manage. Ecol., 2013, 20, 654-361.

Irrgeher, Johanna; Zitek, Andreas; Prohaska, Thomas

2014-05-01

154

The American Counseling Association Practice Research Network (ACA-PRN): A New Research Tool  

ERIC Educational Resources Information Center

This article features the American Counseling Association Practice Research Network (ACA-PRN). Without additional current and ongoing research data, ACA and the counseling profession are seriously hampered when they discuss counseling outcomes. Without a sound, dynamic research base that better articulates the characteristics of practicing…

Bradley, Loretta J.; Sexton, Thomas L.; Smith, Howard B.

2005-01-01

155

Research-tool patents: issues for health in the developing world.  

PubMed

The patent system is now reaching into the tools of medical research, including gene sequences themselves. Many of the new patents can potentially preempt large areas of medical research and lay down legal barriers to the development of a broad category of products. Researchers must therefore consider redesigning their research to avoid use of patented techniques, or expending the effort to obtain licences from those who hold the patents. Even if total licence fees can be kept low, there are enormous negotiation costs, and one "hold-out" may be enough to lead to project cancellation. This is making it more difficult to conduct research within the developed world, and poses important questions for the future of medical research for the benefit of the developing world. Probably the most important implication for health in the developing world is the possible general slowing down and complication of medical research. To the extent that these patents do slow down research, they weaken the contribution of the global research community to the creation and application of medical technology for the benefit of developing nations. The patents may also complicate the granting of concessional prices to developing nations - for pharmaceutical firms that seek to offer a concessional price may have to negotiate arrangements with research-tool firms, which may lose royalties as a result. Three kinds of response are plausible. One is to develop a broad or global licence to permit the patented technologies to be used for important applications in the developing world. The second is to change technical patent law doctrines. Such changes could be implemented in developed and developing nations and could be quite helpful while remaining consistent with TRIPS. The third is to negotiate specific licence arrangements, under which specific research tools are used on an agreed basis for specific applications. These negotiations are difficult and expensive, requiring both scientific and legal skills. But they will be an unavoidable part of international medical research. PMID:11953790

Barton, John H

2002-01-01

156

SSB Training: SSB Basic Querying Tools Self Service Banner Finance Queries for Grants/Sponsored Research  

E-print Network

SSB Training: SSB Basic Querying Tools Self Service Banner Finance Queries for Grants/Sponsored Research Projects This tutorial is focused on using Self Service Banner Finance to run available balance for the Fund, Org and Program code components of the accounting string used in Banner. Logging in to Self

157

Frontiers Reactive transport modeling: An essential tool and a new research approach for the Earth sciences  

Microsoft Academic Search

Reactive transport modeling is an essential tool for the analysis of coupled physical, chemical, and biological processes in Earth systems, and has additional potential to better integrate the results from focused fundamental research on Earth materials. Appropriately designed models can describe the interactions of competing processes at a range of spatial and time scales, and hence are critical for connecting

Carl I. Steefel; Donald J. DePaolo; Peter C. Lichtner

2005-01-01

158

Managing complex research datasets using electronic tools: a meta-analysis exemplar.  

PubMed

Meta-analyses of broad scope and complexity require investigators to organize many study documents and manage communication among several research staff. Commercially available electronic tools, for example, EndNote, Adobe Acrobat Pro, Blackboard, Excel, and IBM SPSS Statistics (SPSS), are useful for organizing and tracking the meta-analytic process as well as enhancing communication among research team members. The purpose of this article is to describe the electronic processes designed, using commercially available software, for an extensive, quantitative model-testing meta-analysis. Specific electronic tools improved the efficiency of (a) locating and screening studies, (b) screening and organizing studies and other project documents, (c) extracting data from primary studies, (d) checking data accuracy and analyses, and (e) communication among team members. The major limitation in designing and implementing a fully electronic system for meta-analysis was the requisite upfront time to decide on which electronic tools to use, determine how these tools would be used, develop clear guidelines for their use, and train members of the research team. The electronic process described here has been useful in streamlining the process of conducting this complex meta-analysis and enhancing communication and sharing documents among research team members. PMID:23681256

Brown, Sharon A; Martin, Ellen E; Garcia, Theresa J; Winter, Mary A; García, Alexandra A; Brown, Adama; Cuevas, Heather E; Sumlin, Lisa L

2013-06-01

159

Virtual Routers: A Tool for Networking Research and Florian Baumgartner, Torsten Braun, Eveline Kurt, Attila Weyland  

E-print Network

Virtual Routers: A Tool for Networking Research and Education Florian Baumgartner, Torsten Braun/3261 [baumgart|braun|kurt|weyland]@iam.unibe.ch] ABSTRACT Virtual routers are software entities, i.e. user space processes, emulating IP routers on one or several (Linux) computers. Virtual routers can be used for both

Braun, Torsten

160

The Ned Davis Research Evolutionary Optimizer (NEO) is a tool that performs  

E-print Network

ABSTRACT The Ned Davis Research Evolutionary Optimizer (NEO) is a tool that performs that form nearly optimal pro- grams for investment timing or asset allo- cation. The primary inputs to NEO- ing signals or asset allocation recommen- dations. 1. Introduction NEO is an efficient generator

Fernandez, Thomas

161

Operations Research Tools for Addressing Current Challenges in Emergency Medical Services  

E-print Network

, the Journal of Emergency Medical Services, or Academic Emergency Medicine. These journals also publishOperations Research Tools for Addressing Current Challenges in Emergency Medical Services Shane G. Henderson March 26, 2009 Abstract Emergency Medical Service (EMS) providers face a host of significant

Henderson, Shane

162

bioinformatics: The research, development, or application of computational tools and approaches for  

E-print Network

bio·in·for·mat·ics: The research, development, or application of computational tools and approaches to establish the university as a national leader in Bioinformatics. Two Board of Regents Enhancement Grants have been obtained by the department for purposes of enhancing the curriculum in bioinformatics and its

Li, X. Rong

163

Basic Reference Tools for Nursing Research. A Workbook with Explanations and Examples.  

ERIC Educational Resources Information Center

This workbook is designed to introduce nursing students to basic concepts and skills needed for searching the literatures of medicine, nursing, and allied health areas for materials relevant to specific information needs. The workbook introduces the following research tools: (1) the National Library of Medicine's MEDLINE searches, including a…

Smalley, Topsy N.

164

FULLANALYZE: A RESEARCH TOOL FOR HANDLING, PROCESSING AND ANALYZING FULL-WAVEFORM LIDAR DATA  

E-print Network

FULLANALYZE: A RESEARCH TOOL FOR HANDLING, PROCESSING AND ANALYZING FULL-WAVEFORM LIDAR DATA A ON FULL-WAVEFORM LIDAR DATA Airborne lidar systems (ALS) provide 3D point clouds of the topography prevention and natural ressource management. Moreover, such active systems, also called "multiple echo lidar

Paris-Sud XI, Université de

165

FULLANALYZE: A RESEARCH TOOL FOR HANDLING, PROCESSING AND ANALYZING FULL-WAVEFORM LIDAR DATA  

E-print Network

FULLANALYZE: A RESEARCH TOOL FOR HANDLING, PROCESSING AND ANALYZING FULL-WAVEFORM LIDAR DATA A) lidar systems provide range profiles of the Earth topography. They are acquired from airborne plat on the 2D/3D interface that gives the possibility to visualize the interaction between the lidar

Paris-Sud XI, Université de

166

Pancreatic Cancer Center: Providing the Research Tools Necessary to Advance Pancreatic Cancer Patient Care  

E-print Network

Pancreatic Cancer Center: Providing the Research Tools Necessary to Advance Pancreatic Cancer the fourth leading cause of cancer deaths, and PDAC patients have a dismal 5-year survival rate of 6 number of NCI-designated cancer centers have a specialized pancreatic cancer program. The creation

Zhou, Yaoqi

167

Community College Fundraising: The Voluntary Support of Education Survey as a Sampling Tool for Research  

ERIC Educational Resources Information Center

This article describes the Voluntary Support for Education (VSE) Survey, an instrument created by the Council for Aid to Education. Our objective is to explain VSE's potential value as a tool to inform both institutional and academic research regarding fund-raising activities at community colleges. Of particular interest is how the data available…

Wagoner, Richard L.; Besikof, Rudolph J.

2011-01-01

168

Fault Tree Analysis: A Research Tool for Educational Planning. Technical Report No. 1.  

ERIC Educational Resources Information Center

This ESEA Title III report describes fault tree analysis and assesses its applicability to education. Fault tree analysis is an operations research tool which is designed to increase the probability of success in any system by analyzing the most likely modes of failure that could occur. A graphic portrayal, which has the form of a tree, is…

Alameda County School Dept., Hayward, CA. PACE Center.

169

Theories, tools and research methods in program comprehension: past, present and future  

Microsoft Academic Search

Program comprehension research can be characterized by both the theories that provide rich explanations about how programmers understand software, as well as the tools that are used to assist in comprehension tasks. In this paper, I review some of the key cognitive theories of program comprehension that have emerged over the past thirty years. Using these theories as a canvas,

Margaret-anne D. Storey

2006-01-01

170

Advancing institutional efforts to support research mentorship: a conceptual framework and self-assessment tool.  

PubMed

The purpose of this article is to assist institutions in advancing their efforts to support research mentorship. The authors begin by describing how institutions can shape the key domains of research mentorship: (1) the criteria for selecting mentors, (2) incentives for motivating faculty to serve effectively as mentors, (3) factors that facilitate the mentor-mentee relationship, (4) factors that strengthen a mentee's ability to conduct research responsibly, and (5) factors that contribute to the professional development of both mentees and mentors. On the basis of a conceptual analysis of these domains as currently documented in the literature, as well as their collective experience examining mentoring programs at a range of academic medicine institutions and departments, the authors provide a framework that leaders of institutions and/or departments can adapt for use as a tool to document and monitor policies for guiding the mentorship process, the programs/activities through which these policies are implemented, and the structures that are responsible for maintaining policies and implementing programs. The authors provide an example of how one hypothetical institution might use the self-assessment tool to track its policies, programs, and structures across the key domains of research mentorship and, on the basis of this information, identify a range of potential actions to strengthen its research mentoring efforts. The authors conclude with a brief discussion of the limitations of the self-assessment tool, the potential drawbacks and benefits of the overall approach, and proposed next steps for research in this area. PMID:18316865

Keyser, Donna J; Lakoski, Joan M; Lara-Cinisomo, Sandraluz; Schultz, Dana J; Williams, Valerie L; Zellers, Darlene F; Pincus, Harold Alan

2008-03-01

171

Online Survey Tools 37 Journal of Empirical Research on Human Research Ethics, PP. 3748. PRINT ISSN 1556-2646, ONLINE ISSN 1556-2654. 2009 BY JOAN SIEBER.  

E-print Network

Online Survey Tools 37 Journal of Empirical Research on Human Research Ethics, PP. 37­48. PRINT and ontological model. Within this new model, a research ethics 2.0 (Buchanan, 2009) emerges, one that is forcing researchers and research regulators to rethink and reevaluate such fundamental research ethics issues

Brusilovsky, Peter

172

New method development in prehistoric stone tool research: evaluating use duration and data analysis protocols.  

PubMed

Lithic microwear is a research field of prehistoric stone tool (lithic) analysis that has been developed with the aim to identify how stone tools were used. It has been shown that laser scanning confocal microscopy has the potential to be a useful quantitative tool in the study of prehistoric stone tool function. In this paper, two important lines of inquiry are investigated: (1) whether the texture of worn surfaces is constant under varying durations of tool use, and (2) the development of rapid objective data analysis protocols. This study reports on the attempt to further develop these areas of study and results in a better understanding of the complexities underlying the development of flexible analytical algorithms for surface analysis. The results show that when sampling is optimised, surface texture may be linked to contact material type, independent of use duration. Further research is needed to validate this finding and test an expanded range of contact materials. The use of automated analytical protocols has shown promise but is only reliable if sampling location and scale are defined. Results suggest that the sampling protocol reports on the degree of worn surface invasiveness, complicating the ability to investigate duration related textural characterisation. PMID:25041833

Evans, Adrian A; Macdonald, Danielle A; Giusca, Claudiu L; Leach, Richard K

2014-10-01

173

Standardized nursing care plan: a case study on developing a tool for clinical research.  

PubMed

The National Institutes of Health have developed a new organizational consortium through a funding mechanism called the Clinical and Translational Science Award. This program funds academic institutions to create a platform for research that expedites the development and delivery of new treatments through open interdisciplinary collaboration. As a result, the adult clinical research center at San Francisco General Hospital is now part of the Clinical and Translational Science Institute at the University of California San Francisco. Nurses on this research unit have begun to employ a standardized nursing care plan that focuses on the particular needs of the research participant, an advancement that if implemented nationwide among all adult clinical research centers will be of paramount importance in fostering a collaborative relationship within the new organizational structure. This standardized nursing care plan will provide research nurses with a tool that will enable them to provide safe and quality patient care. PMID:18263843

Vizoso, Hector; Lyskawa, Meg; Couey, Paul

2008-08-01

174

Information Technology Research Services: Powerful Tools to Keep Up with a Rapidly Moving Field  

NASA Technical Reports Server (NTRS)

Marty firms offer Information Technology Research reports, analyst calls, conferences, seminars, tools, leadership development, etc. These entities include Gartner, Forrester Research, IDC, The Burton Group, Society for Information Management, 1nfoTech Research, The Corporate Executive Board, and so on. This talk will cover how a number of such services are being used at the Goddard Space Flight Center to improve our IT management practices, workforce skills, approach to innovation, and service delivery. These tools and services are used across the workforce, from the executive leadership to the IT worker. The presentation will cover the types of services each vendor provides and their primary engagement model. The use of these services at other NASA Centers and Headquarters will be included. In addition, I will explain how two of these services are available now to the entire NASA IT workforce through enterprise-wide subscriptions.

Hunter, Paul

2010-01-01

175

Development of "-omics" research in Schistosoma spp. and -omics-based new diagnostic tools for schistosomiasis  

PubMed Central

Schistosomiasis, caused by dioecious flatworms in the genus Schistosoma, is torturing people from many developing countries nowadays and frequently leads to severe morbidity and mortality of the patients. Praziquantel based chemotherapy and morbidity control for this disease adopted currently necessitate viable and efficient diagnostic technologies. Fortunately, those “-omics” researches, which rely on high-throughput experimental technologies to produce massive amounts of informative data, have substantially contributed to the exploitation and innovation of diagnostic tools of schistosomiasis. In its first section, this review provides a concise conclusion on the progresses pertaining to schistosomal “-omics” researches to date, followed by a comprehensive section on the diagnostic methods of schistosomiasis, especially those innovative ones based on the detection of antibodies, antigens, nucleic acids, and metabolites with a focus on those achievements inspired by “-omics” researches. Finally, suggestions about the design of future diagnostic tools of schistosomiasis are proposed, in order to better harness those data produced by “-omics” studies. PMID:25018752

Wang, Shuqi; Hu, Wei

2014-01-01

176

Researchers develop tool to determine individual risk of prostate cancer overdiagnosis  

Cancer.gov

Researchers at Fred Hutchinson Cancer Research Center and the University of Washington have developed a personalized tool that can predict the likelihood of prostate cancer overdiagnosis. They announced their findings this week in the online issue of the Journal of the National Cancer Institute. The researchers created a nomogram, a graphical calculating device, that incorporates a patient’s age, prostate-specific antigen (PSA) level and Gleason score – which grades prostate cancer tissue based on how it looks under a microscope – to determine the likelihood that screening-detected prostate cancer has been overdiagnosed.

177

Open Support Platform for Environmental Research (OSPER) - tools for the discovery and exploitation of environmental data  

NASA Astrophysics Data System (ADS)

The Open Support Platform for Environmental Research (OSPER) has been launched to take forward key data management components developed under the Swiss Experiment platform project to achieve improved usability and a wider scope. With this project, we aim to connect users to data and their context, an area identified during SwissEx as having the greatest potential impact on the research community. OSPER has a clear focus on providing the technology for data storage, management and exploitation with a special focus on data interoperability and documentation. In this presentation, we will demonstrate the key aims of OSPER for the period 2012 - 2015. Inheriting the basic SwissEx functionality, OSPER provides an excellent method of making data accessible via their metadata. One of the biggest differences between the OSPER infrastructure and other data platforms is the level of interaction that one can have with the data and the level of integration with the analysis tools used in science. We wish to capitalise on this advantage by increasing this integration and working with environmental research projects to develop the tools that make a difference to their daily research. The new data infrastructure will serve the following purposes: ? Open documentation, archiving and discovery of datasets. ? Facilitation of data sharing and collaboration (especially inter-disciplinary) with data owner controlled access rights, particularly concentrating on providing as much contextual information as possible. ? Improvements in ease of data access and combination of data sources. ? Tools for data visualisation and statistical and numerical data analysis with a focus on spatial data and trends. Key areas identified for development during OSPER are: ? New infrastructure and content for current WebGIS-based data visualisation system to create a publicly available platform. ? Provision of data in standard formats using standard methods as well as the consumption of such data by the processing/visualisation tools. ? Provision of connected tools to provide commonly used functionality. ? Cloud compatibility. ? Greater integration of metadata and data. ? Integration of publications using advances made in the ScienceWise project. ? Advanced queries of 3- and 4-Dimensional data sources. ? Documented examples of spatio-temporal statistical tools. Each of the components of the infrastructure (database middleware, WebGIS, model interfaces and processing/visualization tools) will be designed for usage both within the OSPER system and standalone. They will provide standardized interfaces, such that they can be adapted for use with data from any compatible infrastructure, and such that the data held within OSPER can be visualized or processed using any compatible tools.

Dawes, N. M.; Lehning, M.; Bavay, M.; Sarni, S.; Iosifescu, I.; Gwadera, R.; Scipion, D. E.; Blanchet, J.; Davison, A.; Berne, A.; Hurni, L.; Parlange, M. B.; Aberer, K.

2012-12-01

178

Community-based participatory research as a tool to advance environmental health sciences.  

PubMed Central

The past two decades have witnessed a rapid proliferation of community-based participatory research (CBPR) projects. CBPR methodology presents an alternative to traditional population-based biomedical research practices by encouraging active and equal partnerships between community members and academic investigators. The National Institute of Environmental Health Sciences (NIEHS), the premier biomedical research facility for environmental health, is a leader in promoting the use of CBPR in instances where community-university partnerships serve to advance our understanding of environmentally related disease. In this article, the authors highlight six key principles of CBPR and describe how these principles are met within specific NIEHS-supported research investigations. These projects demonstrate that community-based participatory research can be an effective tool to enhance our knowledge of the causes and mechanisms of disorders having an environmental etiology, reduce adverse health outcomes through innovative intervention strategies and policy change, and address the environmental health concerns of community residents. PMID:11929724

O'Fallon, Liam R; Dearry, Allen

2002-01-01

179

Accumulating Evidence and Research Organization (AERO) model: a new tool for representing, analyzing, and planning a translational research program  

PubMed Central

Background Maximizing efficiency in drug development is important for drug developers, policymakers, and human subjects. Limited funds and the ethical imperative of risk minimization demand that researchers maximize the knowledge gained per patient-subject enrolled. Yet, despite a common perception that the current system of drug development is beset by inefficiencies, there remain few approaches for systematically representing, analyzing, and communicating the efficiency and coordination of the research enterprise. In this paper, we present the first steps toward developing such an approach: a graph-theoretic tool for representing the Accumulating Evidence and Research Organization (AERO) across a translational trajectory. Methods This initial version of the AERO model focuses on elucidating two dimensions of robustness: (1) the consistency of results among studies with an identical or similar outcome metric; and (2) the concordance of results among studies with qualitatively different outcome metrics. The visual structure of the model is a directed acyclic graph, designed to capture these two dimensions of robustness and their relationship to three basic questions that underlie the planning of a translational research program: What is the accumulating state of total evidence? What has been the translational trajectory? What studies should be done next? Results We demonstrate the utility of the AERO model with an application to a case study involving the antibacterial agent, moxifloxacin, for the treatment of drug-susceptible tuberculosis. We then consider some possible elaborations for the AERO model and propose a number of ways in which the tool could be used to enhance the planning, reporting, and analysis of clinical trials. Conclusion The AERO model provides an immediate visual representation of the number of studies done at any stage of research, depicting both the robustness of evidence and the relationship of each study to the larger translational trajectory. In so doing, it makes some of the invisible or inchoate properties of the research system explicit – helping to elucidate judgments about the accumulating state of evidence and supporting decision-making for future research. PMID:23721523

2013-01-01

180

A Consortium for Enhanced Access to Patented Research Tools: Japanese Policy and Proposal of a Novel Scheme  

Microsoft Academic Search

Currently, in Japan and other developed countries, massive amounts of research funds, including government funds, are being poured into basic research conducted by universities and public research institutions in the area of life science. From such academic research, a number of innovations ultimately leading to the development of new medicines are attained. However, the existence of patents for research tools

Koichi Sumikura

2007-01-01

181

Toole 8/28/2007 page 1 A Primer on Social Science Research Methods in Construction1  

E-print Network

Toole 8/28/2007 page 1 A Primer on Social Science Research Methods in Construction1 T. Michael that effective construction research requires proper application of social science research methods on construction research methods, six principles of social science research methods are presented and illustrated

Toole, T. Michael

182

A new research tool for hybrid Bayesian networks using script language  

NASA Astrophysics Data System (ADS)

While continuous variables become more and more inevitable in Bayesian networks for modeling real-life applications in complex systems, there are not much software tools to support it. Popular commercial Bayesian network tools such as Hugin, and Netica etc., are either expensive or have to discretize continuous variables. In addition, some free programs existing in the literature, commonly known as BNT, GeNie/SMILE, etc, have their own advantages and disadvantages respectively. In this paper, we introduce a newly developed Java tool for model construction and inference for hybrid Bayesian networks. Via the representation power of the script language, this tool can build the hybrid model automatically based on a well defined string that follows the specific grammars. Furthermore, it implements several inference algorithms capable to accommodate hybrid Bayesian networks, including Junction Tree algorithm (JT) for conditional linear Gaussian model (CLG), and Direct Message Passing (DMP) for general hybrid Bayesian networks with CLG structure. We believe this tool will be useful for researchers in the field.

Sun, Wei; Park, Cheol Young; Carvalho, Rommel

2011-06-01

183

Exploring Assessment Tools for Research and Evaluation in Astronomy Education and Outreach  

NASA Astrophysics Data System (ADS)

The ability to effectively measure knowledge, attitudes, and skills in formal and informal educational settings is an important aspect of astronomy education research and evaluation. Assessments may take the form of interviews, observations, surveys, exams, or other probes to help unpack people's understandings or beliefs. In this workshop, we discussed characteristics of a variety of tools that exist to assess understandings of different concepts in astronomy as well as attitudes towards science and science teaching; these include concept inventories, surveys, interview protocols, observation protocols, card sorting, reflection videos, and other methods currently being used in astronomy education research and EPO program evaluations. In addition, we discussed common questions in the selection of assessment tools including issues of reliability and validity, time to administer, format of implementation, analysis, and human subject concerns.

Buxner, S. R.; Wenger, M. C.; Dokter, E. F. C.

2011-09-01

184

PublicationHarvester: An open-source software tool for science policy research  

Microsoft Academic Search

We present PublicationHarvester, an open-source software tool for gathering publication information on individual life scientists. The software interfaces with MEDLINE, and allows the end-user to specify up to four MEDLINE-formatted names for each researcher. Using these names along with a user-specified search query, PublicationHarvester generates yearly publication counts, optionally weighted by Journal Impact Factors. These counts are further broken-down by

Pierre Azoulay; Andrew Stellman; Joshua Graff Zivin

2006-01-01

185

Informatics tools to improve clinical research study implementation. | accrualnet.cancer.gov  

Cancer.gov

In complex multisite clinical research trials, potential problems are compounded when multiple personnel at different sites are responsible for primary data collection, data entry, report form design, etc. This article describes how informatics tools can help identify and correct flawed procedures and data problems early, contributing to overall study success. For example, a value that is flagged as “bad” soon after data entry is more likely to be correctable because source documents and data originators are more readily available.

186

Transcript-based computer animation of movement: Evaluating a new tool for nonverbal behavior research  

Microsoft Academic Search

A new approach for the use of computer animation in experimental nonverbal research is introduced. The method was evaluated\\u000a in a pilot study comparing video recordings of movement in dyadic interactions with computer animations based on transcripts\\u000a of the behavior, to determine whether similar impression effects could be obtained. At the core of our development is a software\\u000a tool allowing

Gary Bente; Anita Petersen; Nicole C. Krämer; Jan Peter de Ruiter

2001-01-01

187

The virtual supermarket: An innovative research tool to study consumer food purchasing behaviour  

PubMed Central

Background Economic interventions in the food environment are expected to effectively promote healthier food choices. However, before introducing them on a large scale, it is important to gain insight into the effectiveness of economic interventions and peoples' genuine reactions to price changes. Nonetheless, because of complex implementation issues, studies on price interventions are virtually non-existent. This is especially true for experiments undertaken in a retail setting. We have developed a research tool to study the effects of retail price interventions in a virtual-reality setting: the Virtual Supermarket. This paper aims to inform researchers about the features and utilization of this new software application. Results The Virtual Supermarket is a Dutch-developed three-dimensional software application in which study participants can shop in a manner comparable to a real supermarket. The tool can be used to study several food pricing and labelling strategies. The application base can be used to build future extensions and could be translated into, for example, an English-language version. The Virtual Supermarket contains a front-end which is seen by the participants, and a back-end that enables researchers to easily manipulate research conditions. The application keeps track of time spent shopping, number of products purchased, shopping budget, total expenditures and answers on configurable questionnaires. All data is digitally stored and automatically sent to a web server. A pilot study among Dutch consumers (n = 66) revealed that the application accurately collected and stored all data. Results from participant feedback revealed that 83% of the respondents considered the Virtual Supermarket easy to understand and 79% found that their virtual grocery purchases resembled their regular groceries. Conclusions The Virtual Supermarket is an innovative research tool with a great potential to assist in gaining insight into food purchasing behaviour. The application can be obtained via an URL and is freely available for academic use. The unique features of the tool include the fact that it enables researchers to easily modify research conditions and in this way study different types of interventions in a retail environment without a complex implementation process. Finally, it also maintains researcher independence and avoids conflicts of interest that may arise from industry collaboration. PMID:21787391

2011-01-01

188

Low Cost Electroencephalographic Acquisition Amplifier to serve as Teaching and Research Tool  

PubMed Central

We describe the development and testing of a low cost, easily constructed electroencephalographic acquisition amplifier for noninvasive Brain Computer Interface (BCI) education and research. The acquisition amplifier is constructed from newly available off-the-shelf integrated circuit components, and readily sends a 24-bit data stream via USB bus to a computer platform. We demonstrate here the hardware’s use in the analysis of a visually evoked P300 paradigm for a choose one-of-eight task. This clearly shows the applicability of this system as a low cost teaching and research tool. PMID:22254699

Jain, Ankit; Kim, Insoo; Gluckman, Bruce J.

2012-01-01

189

Utilizing Geographic Information Systems (GIS) to Influence State Policy: A new descriptive, diagnostic, and analytical tool for higher education research  

Microsoft Academic Search

Abstract The purpose of this paper is to examine the utility of Geographic Information Systems (GIS) as a descriptive, diagnostic and analytical tool in higher education research and public policy development. In this paper GIS and how it has been used as a research tool in higher education and other disciplines is described, and a state level example of how

Nathan Daun-Barnett; Britany Affolter-Caine

2005-01-01

190

Metaphors and Drawings as Research Tools of Head Teachers' Perceptions on Their Management and Leadership Roles and Responsibilities  

ERIC Educational Resources Information Center

This article introduces an alternative qualitative research tool: metaphor and drawing, as projections of personality features, to explore underlying concepts and values, thoughts and beliefs, fears and hesitations, aspirations and ambitions of the research subjects. These two projective tools are used to explore Greek state kindergarten head…

Argyropoulou, Eleftheria; Hatira, Kalliopi

2014-01-01

191

NASA System-Level Design, Analysis and Simulation Tools Research on NextGen  

NASA Technical Reports Server (NTRS)

A review of the research accomplished in 2009 in the System-Level Design, Analysis and Simulation Tools (SLDAST) of the NASA's Airspace Systems Program is presented. This research thrust focuses on the integrated system-level assessment of component level innovations, concepts and technologies of the Next Generation Air Traffic System (NextGen) under research in the ASP program to enable the development of revolutionary improvements and modernization of the National Airspace System. The review includes the accomplishments on baseline research and the advancements on design studies and system-level assessment, including the cluster analysis as an annualization standard of the air traffic in the U.S. National Airspace, and the ACES-Air MIDAS integration for human-in-the-loop analyzes within the NAS air traffic simulation.

Bardina, Jorge

2011-01-01

192

Extending the XNAT archive tool for image and analysis management in ophthalmology research  

NASA Astrophysics Data System (ADS)

In ophthalmology, various modalities and tests are utilized to obtain vital information on the eye's structure and function. For example, optical coherence tomography (OCT) is utilized to diagnose, screen, and aid treatment of eye diseases like macular degeneration or glaucoma. Such data are complemented by photographic retinal fundus images and functional tests on the visual field. DICOM isn't widely used yet, though, and frequently images are encoded in proprietary formats. The eXtensible Neuroimaging Archive Tool (XNAT) is an open-source NIH-funded framework for research PACS and is in use at the University of Iowa for neurological research applications. Its use for ophthalmology was hence desirable but posed new challenges due to data types thus far not considered and the lack of standardized formats. We developed custom tools for data types not natively recognized by XNAT itself using XNAT's low-level REST API. Vendor-provided tools can be included as necessary to convert proprietary data sets into valid DICOM. Clients can access the data in a standardized format while still retaining the original format if needed by specific analysis tools. With respective project-specific permissions, results like segmentations or quantitative evaluations can be stored as additional resources to previously uploaded datasets. Applications can use our abstract-level Python or C/C++ API to communicate with the XNAT instance. This paper describes concepts and details of the designed upload script templates, which can be customized to the needs of specific projects, and the novel client-side communication API which allows integration into new or existing research applications.

Wahle, Andreas; Lee, Kyungmoo; Harding, Adam T.; Garvin, Mona K.; Niemeijer, Meindert; Sonka, Milan; Abràmoff, Michael D.

2013-03-01

193

VoiceThread as a Peer Review and Dissemination Tool for Undergraduate Research  

NASA Astrophysics Data System (ADS)

VoiceThread has been utilized in an undergraduate research methods course for peer review and final research project dissemination. VoiceThread (http://www.voicethread.com) can be considered a social media tool, as it is a web-based technology with the capacity to enable interactive dialogue. VoiceThread is an application that allows a user to place a media collection online containing images, audio, videos, documents, and/or presentations in an interface that facilitates asynchronous communication. Participants in a VoiceThread can be passive viewers of the online content or engaged commenters via text, audio, video, with slide annotations via a doodle tool. The VoiceThread, which runs across browsers and operating systems, can be public or private for viewing and commenting and can be embedded into any website. Although few university students are aware of the VoiceThread platform (only 10% of the students surveyed by Ng (2012)), the 2009 K-12 edition of The Horizon Report (Johnson et al., 2009) lists VoiceThread as a tool to watch because of the opportunities it provides as a collaborative learning environment. In Fall 2011, eleven students enrolled in an undergraduate research methods course at Penn State Brandywine each conducted their own small-scale research project. Upon conclusion of the projects, students were required to create a poster summarizing their work for peer review. To facilitate the peer review process outside of class, each student-created PowerPoint file was placed in a VoiceThread with private access to only the class members and instructor. Each student was assigned to peer review five different student posters (i.e., VoiceThread images) with the audio and doodle tools to comment on formatting, clarity of content, etc. After the peer reviews were complete, the students were allowed to edit their PowerPoint poster files for a new VoiceThread. In the new VoiceThread, students were required to video record themselves describing their research and taking the viewer through their poster in the VoiceThread. This new VoiceThread with their final presentations was open for public viewing but not public commenting. A formal assessment was not conducted on the student impact of using VoiceThread for peer review and final research presentations. From an instructional standpoint, requiring students to use audio for the peer review commenting seemed to result in lengthier and more detailed reviews, connected with specific poster features when the doodle tool was utilized. By recording themselves as a "talking head" for the final product, students were required to be comfortable and confident with presenting their research, similar to what would be expected at a conference presentation. VoiceThread is currently being tested in general education Earth science courses at Penn State Brandywine as a dissemination tool for classroom-based inquiry projects and recruitment tool for Earth & Mineral Science majors.

Guertin, L. A.

2012-12-01

194

The development of a two-component force dynamometer and tool control system for dynamic machine tool research  

NASA Technical Reports Server (NTRS)

The development is presented of a tooling system that makes a controlled sinusoidal oscillation simulating a dynamic chip removal condition. It also measures the machining forces in two mutually perpendicular directions without any cross sensitivity.

Sutherland, I. A.

1973-01-01

195

Main influencing factors and health-related quality of life issues in patients with oesophago-gastric cancer - as measured by EORTC tools  

PubMed Central

Aim of the study To assess influencing factors and main health-related quality of life (HRQoL) issues in patients with cancers of the oesophago-gastric region using the European Organization for Research and Treatment of Cancer (EORTC) quality of life questionnaire Core 30 (QLQ-C30) and its oesophago-gastric module (QLQ-OG25). Material and methods Patients were qualified for this study based on the histological confirmation of oesophageal, oesophago-gastric or gastric cancers. Each patient filled out the Polish version of the EORTC QLQ-C30, the QLQ-OG25 module and a personal questionnaire. Patients were divided into groups based on gender, age, treatment intention, tumour localization, working status and level of education. Results Our study included 112 patients – 39 women (35%) and 73 men (mean age ± SD; 60.2 ±10.9). Thirty-five patients (31.3%) completed the questionnaires twice. Eighty-four (75%) patients had gastric cancer (GC), twenty-six (23.2%) oesophageal cancer (OC) and two (1.8%) cancer of the oesophago-gastric junction (OGJC). Eighty (71.4%) patients underwent surgical treatment prior to either chemo-, radio- or chemoradiotherapy. The Global Health Status scale of the QLQ-C30 inversely correlated with all the other QLQ-C30 and QLQ-OG25 symptom scales (r = –0.26 to –0.61; p < 0.05). Conclusions The main HRQoL problems of Polish OC, OGJC and GC patients are fatigue, insomnia, anxiety, and appetite and weight loss. Older age, receiving palliative treatment, having gastric cancer, being on retirement and having lower education are factors associated with higher symptom scores (worse symptoms) and thus poorer HRQoL. PMID:24596521

Puskulluoglu, Miroslawa; Biesiada, Katarzyna; Bochenek, Justyna; Ochenduszko, Sebastian; Tomaszewska, Iwona M.; Krzemieniecki, Krzysztof

2013-01-01

196

The concept map as a research and evaluation tool: Further evidence of validity  

NASA Astrophysics Data System (ADS)

This study sought further evidence of the concurrent validity of concept mapping as a research and evaluation tool in science education. Specifically, the study examined the extent to which differences exist in the concept maps of advanced college biology majors (N = 25) and beginning nonmajors (N = 25) in the domain of mammals. Furthermore, it explored whether these differences are reflected in the way subjects assign class membership as revealed in a card sorting task. The results indicate that concept maps of biology majors are structurally more complex than those of nonmajors and that differences in the structural complexity and organizational patterns depicted in concept maps are reflected in the underlying dimensions used to assign class membership. Together, these findings suggest that the concept map provides a theoretically powerful and psychometrically sound tool for assessing conceptual change in experimental and classroom settings.

Markham, Kimberly M.; Mintzes, Joel J.; Jones, M. Gail

197

Research on test techniques of fault forewarning and diagnosis for high-end CNC machine tool  

NASA Astrophysics Data System (ADS)

With the progress of modern science and technique, the manufacturing industry becomes more and more complex and intelligent. It is the challenge for stable, safe running and economical efficiency of machining equipment such as high-quality numerical control because of its complex structure and integrated functions, and the potential faults are easy to happen. How to ensure the equipment runs stably and reliably becomes the key problem to improve the machining precision and efficiency. In order to prolong the average no-fault time, stable running and machining precision of numerical control, it is very important to make relative test and research on acquisition of data of numerical control sample and establishment of sample database. Take high-end CNC Machine Tool for example, the research on test techniques for data acquisition of sample of typical functional parts in CNC Machine Tool will be made and test condition will be set up; the test methods for sample acquisition on running state monitoring and fault forewarning and diagnosis of numerical control is determined; the test platform for typical functional parts of numerical control is established; the sample database is designed and the sample base and knowledge mode is made. The test and research provide key test techniques to disclosure dynamic performance of fault and precision degeneration, and analyze the impact factors to fault.

Ren, Bin; Xu, Xiaoli

2010-12-01

198

[The use of interviews in participative intervention and research: the GAM tool as a collective interview].  

PubMed

This paper seeks to assess a way of conducting interviews in line with the ideology of Brazilian Psychiatric Reform. In the methodology of participative intervention and research in mental health, the interview is less a data collection than a data harvesting procedure. It is designed to apply the principles of psychosocial care, autonomy as the basis for treatment, the predominance of the users and of their social networks and civic participation. Inspired by the Explicitation Interview technique, the contention is that the handling of the interview presupposes an open attitude able to promote and embrace different viewpoints. This attitude makes the interview a collective experience of sharing and belonging, allowing participants to reposition themselves subjectively in treatment with the emergence of groupality. As an example of using the interview as a methodological tool in mental health research, we examine research into adaptation of the tool of Autonomous Medication Management (GAM). It is an interventionist approach guided by principles that foster autonomy and the protagonist status of users of psychotropic medication, their quality of life, their rights and recognition of the multiple significances of medication, understood here as a collective interview technique. PMID:24061008

Sade, Christian; de Barros, Leticia Maria Renault; Melo, Jorge José Maciel; Passos, Eduardo

2013-10-01

199

Oxytocin and Vasopressin Agonists and Antagonists as Research Tools and Potential Therapeutics  

PubMed Central

We recently reviewed the status of peptide and nonpeptide agonists and antagonists for the V1a, V1b and V2 receptors for arginine vasopressin (AVP) and the oxytocin receptor for oxytocin (OT). In the present review, we update the status of peptides and nonpeptides as: (i) research tools and (ii) therapeutic agents. We also present our recent findings on the design of fluorescent ligands for V1b receptor localisation and for OT receptor dimerisation. We note the exciting discoveries regarding two novel naturally occurring analogues of OT. Recent reports of a selective VP V1a agonist and a selective OT agonist point to the continued therapeutic potential of peptides in this field. To date, only two nonpeptides, the V2/V1a antagonist, conivaptan and the V2 antagonist tolvaptan have received Food and Drug Administration approval for clinical use. The development of nonpeptide AVP V1a, V1b and V2 antagonists and OT agonists and antagonists has recently been abandoned by Merck, Sanofi and Pfizer. A promising OT antagonist, Retosiban, developed at Glaxo SmithKline is currently in a Phase II clinical trial for the prevention of premature labour. A number of the nonpeptide ligands that were not successful in clinical trials are proving to be valuable as research tools. Peptide agonists and antagonists continue to be very widely used as research tools in this field. In this regard, we present receptor data on some of the most widely used peptide and nonpeptide ligands, as a guide for their use, especially with regard to receptor selectivity and species differences. PMID:22375852

Manning, M; Misicka, A; Olma, A; Bankowski, K; Stoev, S; Chini, B; Durroux, T; Mouillac, B; Corbani, M; Guillon, G

2012-01-01

200

10/6/13 Researchers develop new search tool to help fight child porn, catch cyber thieves -Yahoo India Finance in.finance.yahoo.com/news/researchers-develop-search-tool-help-091916114.html 1/1  

E-print Network

10/6/13 Researchers develop new search tool to help fight child porn, catch cyber thieves - Yahoo porn, catch cyber thieves ANI ­ Thu 6 Jun, 2013 2:49 PM IST Montreal, June 6 (ANI): A new search tool

Fung, Benjamin C. M.

201

Solid Modeling Aerospace Research Tool (SMART) user's guide, version 2.0  

NASA Technical Reports Server (NTRS)

The Solid Modeling Aerospace Research Tool (SMART) software package is used in the conceptual design of aerospace vehicles. It provides a highly interactive and dynamic capability for generating geometries with Bezier cubic patches. Features include automatic generation of commonly used aerospace constructs (e.g., wings and multilobed tanks); cross-section skinning; wireframe and shaded presentation; area, volume, inertia, and center-of-gravity calculations; and interfaces to various aerodynamic and structural analysis programs. A comprehensive description of SMART and how to use it is provided.

Mcmillin, Mark L.; Spangler, Jan L.; Dahmen, Stephen M.; Rehder, John J.

1993-01-01

202

Synthetic biology in mammalian cells: Next generation research tools and therapeutics  

PubMed Central

Recent progress in DNA manipulation and gene circuit engineering has greatly improved our ability to programme and probe mammalian cell behaviour. These advances have led to a new generation of synthetic biology research tools and potential therapeutic applications. Programmable DNA-binding domains and RNA regulators are leading to unprecedented control of gene expression and elucidation of gene function. Rebuilding complex biological circuits such as T cell receptor signalling in isolation from their natural context has deepened our understanding of network motifs and signalling pathways. Synthetic biology is also leading to innovative therapeutic interventions based on cell-based therapies, protein drugs, vaccines and gene therapies. PMID:24434884

Lienert, Florian; Lohmueller, Jason J; Garg, Abhishek; Silver, Pamela A

2014-01-01

203

Ocular static and dynamic light scattering: a noninvasive diagnostic tool for eye research and clinical practice  

NASA Technical Reports Server (NTRS)

The noninvasive techniques of static and dynamic light scattering are emerging as valuable diagnostic tools for the early detection of ocular and systemic diseases. These include corneal abnormalities, pigmentary dispersion syndrome, glaucoma, cataract, diabetic vitreopathy, and possibly macular degeneration. Systemic conditions such as diabetes and possibly Alzheimer's disease can potentially be detected early via ocular tissues. The current state of development of these techniques for application to ophthalmic research and ultimately clinical practice is reviewed. (c) 2004 Society of Photo-Optical Instrumentation Engineers.

Ansari, Rafat R.

2004-01-01

204

High Resolution X-ray Computed Tomography: An Emerging Tool for Small Animal Cancer Research1  

PubMed Central

Abstract Dedicated high-resolution small animal imaging systems have recently emerged as important new tools for cancer research. These new imaging systems permit researchers to noninvasively screen animals for mutations or pathologies and to monitor disease progression and response to therapy. One imaging modality, X-ray microcomputed tomography (microCT) shows promise as a cost-effective means for detecting and characterizing soft-tissue structures, skeletal abnormalities, and tumors in live animals. MicroCT systems provide high-resolution images (typically 50 microns or less), rapid data acquisition (typically 5 to 30 minutes), excellent sensitivity to skeletal tissue and good sensitivity to soft tissue, particularly when contrast-enhancing media are employed. The development of microCT technology for small animal imaging is reviewed, and key considerations for designing small animal microCT imaging protocols are summarized. Recent studies on mouse prostate, lung and bone tumor models are overviewed. PMID:10933069

Paulus, Michael J; Gleason, Shaun S; Kennel, Stephen J; Hunsicker, Patricia R; Johnson, Dabney K

2000-01-01

205

Software Tools for Academics and Researchers Biochem: Protein 3-D Viewer  

NSDL National Science Digital Library

Created by researchers at MIT's Software Tools for Academics and Researchers (STAR) initiative, this website offers interested parties a 3-D protein viewer that "allows students to learn key concepts about the biology of proteins in an interactive manner." First-time users may want to start by clicking on the "Video Tutorial" on the homepage to get a basic sense of how the viewer works. The site also includes a "Screenshots" section and several sample exercises. Perhaps the most detailed instructions can be found in the online user manual, which includes eight areas, including "Loading a protein structure" and "Visualizing atoms and bonds." A section where users can send in feedback rounds out the site.

2012-01-06

206

Near-infrared spectroscopy (NIRS) as a new tool for neuroeconomic research  

PubMed Central

Over the last decade, the application of neuroscience to economic research has gained in importance and the number of neuroeconomic studies has grown extensively. The most common method for these investigations is fMRI. However, fMRI has limitations (particularly concerning situational factors) that should be countered with other methods. This review elaborates on the use of functional Near-Infrared Spectroscopy (fNIRS) as a new and promising tool for investigating economic decision making both in field experiments and outside the laboratory. We describe results of studies investigating the reliability of prototype NIRS studies, as well as detailing experiments using conventional and stationary fNIRS devices to analyze this potential. This review article shows that further research using mobile fNIRS for studies on economic decision making outside the laboratory could be a fruitful avenue helping to develop the potential of a new method for field experiments outside the laboratory. PMID:25147517

Kopton, Isabella M.; Kenning, Peter

2014-01-01

207

Lower body negative pressure as a tool for research in aerospace physiology and military medicine  

NASA Technical Reports Server (NTRS)

Lower body negative pressure (LBNP) has been extensively used for decades in aerospace physiological research as a tool to investigate cardiovascular mechanisms that are associated with or underlie performance in aerospace and military environments. In comparison with clinical stand and tilt tests, LBNP represents a relatively safe methodology for inducing highly reproducible hemodynamic responses during exposure to footward fluid shifts similar to those experienced under orthostatic challenge. By maintaining an orthostatic challenge in a supine posture, removal of leg support (muscle pump) and head motion (vestibular stimuli) during LBNP provides the capability to isolate cardiovascular mechanisms that regulate blood pressure. LBNP can be used for physiological measurements, clinical diagnoses and investigational research comparisons of subject populations and alterations in physiological status. The applications of LBNP to the study of blood pressure regulation in spaceflight, groundbased simulations of low gravity, and hemorrhage have provided unique insights and understanding for development of countermeasures based on physiological mechanisms underlying the operational problems.

Convertino, V. A.

2001-01-01

208

The Frequency and Placement of Main Ideas in Children's Social Studies Textbooks: A Modified Replication of Braddock's Research on Topic Sentences  

Microsoft Academic Search

Braddock (1974) evaluated adult, expository reading materials for the frequency and placement of topic sentences (main ideas). Results indicated that relatively infrequently were main ideas directly stated in expository prose, and that paragraphs opened with a simple topic sentence only 13% of the time. This study was a modified replication of Braddock's research in which second-, fourth-, sixth-, and eighth-grade

James F. Baumann; Judith K. Serra

1984-01-01

209

Laboratory directed research and development final report: Intelligent tools for on-machine acceptance of precision machined components  

SciTech Connect

On-Machine Acceptance (OMA) is an agile manufacturing concept being developed for machine tools at SNL. The concept behind OMA is the integration of product design, fabrication, and qualification processes by using the machining center as a fabrication and inspection tool. This report documents the final results of a Laboratory Directed Research and Development effort to qualify OMA.

Christensen, N.G.; Harwell, L.D.; Hazelton, A.

1997-02-01

210

miRspring: a compact standalone research tool for analyzing miRNA-seq data  

PubMed Central

High-throughput sequencing for microRNA (miRNA) profiling has revealed a vast complexity of miRNA processing variants, but these are difficult to discern for those without bioinformatics expertise and large computing capability. In this article, we present miRNA Sequence Profiling (miRspring) (http://mirspring.victorchang.edu.au), a software solution that creates a small portable research document that visualizes, calculates and reports on the complexities of miRNA processing. We designed an index-compression algorithm that allows the miRspring document to reproduce a complete miRNA sequence data set while retaining a small file size (typically <3 MB). Through analysis of 73 public data sets, we demonstrate miRspring’s features in assessing quality parameters, miRNA cluster expression levels and miRNA processing. Additionally, we report on a new class of miRNA variants, which we term seed-isomiRs, identified through the novel visualization tools of the miRspring document. Further investigation identified that ?30% of human miRBase entries are likely to have a seed-isomiR. We believe that miRspring will be a highly useful research tool that will enhance the analysis of miRNA data sets and thus increase our understanding of miRNA biology. PMID:23775795

Humphreys, David T.; Suter, Catherine M.

2013-01-01

211

The Virtual Museum for Meteorites: an Online Tool for Researchers Educators and Students  

NASA Astrophysics Data System (ADS)

The Virtual Museum for Meteorites (Figure 1) was created as a tool for students, educators and researchers [1, 2]. One of the aims of this online resource is to promote the interest in meteorites. Thus, the role of meteorites in education and outreach is fundamental, as these are very valuable tools to promote the public's interest in Astronomy and Planetary Sciences. Meteorite exhibitions reveal the fascination of students, educators and even researchers for these extraterrestrial rocks and how these can explain many key questions origin and evolution of our Solar System. However, despite the efforts related to the origin and evolution of our Solar System. However, despite the efforts of private collectors, museums and other institutions to organize meteorite exhibitions, the reach of these is usually limited. The Virtual Museum for Meteorites takes advantage of HTML and related technologies to overcome local boundaries and offer its contents for a global audience. A description of the recent developments performed in the framework of this virtual museum is given in this work.

Madiedo, J. M.

2013-09-01

212

Implementing an International Consultation on Earth System Research Priorities Using Web 2.0 Tools  

NASA Astrophysics Data System (ADS)

Leah Goldfarb, Paul Cutler, Andrew Yang*, Mustapha Mokrane, Jacinta Legg and Deliang Chen The scientific community has been engaged in developing an international strategy on Earth system research. The initial consultation in this “visioning” process focused on gathering suggestions for Earth system research priorities that are interdisciplinary and address the most pressing societal issues. It was implemented this through a website that utilized Web 2.0 capabilities. The website (http://www.icsu-visioning.org/) collected input from 15 July to 1 September 2009. This consultation was the first in which the international scientific community was asked to help shape the future of a research theme. The site attracted over 7000 visitors from 133 countries, more than 1000 of whom registered and took advantage of the site’s functionality to contribute research questions (~300 questions), comment on posts, and/or vote on questions. To facilitate analysis of results, the site captured a small set of voluntary information about each contributor and their contribution. A group of ~50 international experts were invited to analyze the inputs at a “Visioning Earth System Research” meeting held in September 2009. The outcome of this meeting—a prioritized list of research questions to be investigated over the next decade—was then posted on the visioning website for additional comment from the community through an online survey tool. In general, many lessons were learned in the development and implementation of this website, both in terms of the opportunities offered by Web 2.0 capabilities and the application of these capabilities. It is hoped that this process may serve as a model for other scientific communities. The International Council for Science (ICSU) in cooperation with the International Social Science Council (ISSC) is responsible for organizing this Earth system visioning process.

Goldfarb, L.; Yang, A.

2009-12-01

213

DataUp 2.0: Improving On a Tool For Helping Researchers Archive, Manage, and Share Their Tabular Data  

NASA Astrophysics Data System (ADS)

There are many barriers to data management and sharing among earth and environmental scientists; among the most significant are a lack of knowledge about best practices for data management, metadata standards, or appropriate data repositories for archiving and sharing data. Last year we developed an open source web application, DataUp, to help researchers overcome these barriers. DataUp helps scientists to (1) determine whether their file is CSV compatible, (2) generate metadata in a standard format, (3) retrieve an identifier to facilitate data citation, and (4) deposit their data into a repository. With funding from the NSF via a supplemental grant to the DataONE project, we are working to improve upon DataUp. Our main goal for DataUp 2.0 is to ensure organizations and repositories are able to adopt and adapt DataUp to meet their unique needs, including connecting to analytical tools, adding new metadata schema, and expanding the list of connected data repositories. DataUp is a collaborative project between the California Digital Library, DataONE, the San Diego Supercomputing Center, and Microsoft Research Connections.

Strasser, C.; Borda, S.; Cruse, P.; Kunze, J.

2013-12-01

214

Ambient Particulate Matter during MILAGRO in Mexico City: Main Findings, Impacts (on AQ and Climate), and Future Research Needs  

NASA Astrophysics Data System (ADS)

The MILAGRO campaign was a large international field experiments conduced in Mexico City and Central Mexico during March 2006. We present an overview of the main findings related to particulate matter and aerosol radiative properties. PM levels inside Mexico City were similar or higher than those in the most polluted North American cities, but ~5 times lower than levels in the most polluted Asian megacities During the study, PM10 and PM2.5 concentrations in the urban area of were about double the concentrations in the rural areas surrounding Mexico City. PM2.5 made up about half of the PM10 concentrations, with small amounts of mass in the PM2.5-PM1.0 range. Mineral matter made up approximately 25% of the PM10 and on average 15% and 28% of the PM2.5 in the urban and rural areas, respectively. Approximately 25% of the PM2.5 was secondary inorganic ions with the remaining PM2.5 mass being comprised of largely carbonaceous aerosol. Except for surface measurements at the central sampling sites in Mexico city, the elemental carbon mass absorption efficiency was relatively constant for aircraft and surface measurements throughout the study, contrary to expectations. Although different organic aerosol (OA) source apportionment methods had some differences, there was agreement that the dominant sources of carbonaceous aerosol were secondary OA (SOA), biomass burning, and mobile sources. The impact of biomass burning to the aerosol outflow from the region was much larger than to the surface concentrations inside the city. SOA formation from primary semivolatile and intermediate volatility precursors has the potential to close the gap in predicted vs. measured SOA, while formation from glyoxal also makes an important contribution, especially to organic oxygen. Biogenic SOA advected from the coastal mountain ranges contributes about 1 ?g m-3 to concentrations in the MCMA. Primary OA from anthropogenic and biomass burning sources was found to be semivolatile, while secondary OA was less volatile than POA and aged SOA was essentially non-volatile, in contradiction with current models. Growth rates of new particle formation in Mexico City was very large and found to be impacted by nitrogen containing organic compounds, organic acids, and hydroxyl organic acids, with only a smaller fraction of sulfate aerosol. Some open research questions include the following: additional work is needed to fully quantify the sources of substantial (30-45%) modern carbon in organic aerosols during low biomass burning periods. Discrepancies between the two modern carbon datasets deserve further study. The impact of regional dust vs. road resuspension, as well as heterogeneous reactions of HNO3 with dust need to be quantified. The impact of some POA sources such as food cooking, biofuel use, and open trash burning may be important, but remains poorly characterized. Some differences in the apportionment of biomass burning PM between different approaches were observed and need further research, as these techniques together represent the state of the art for source apportionment. Anthropogenic SOA predictions are improving in terms of magnitude but are poorly constrained by the data. More specific precursor, intermediate, and tracer measurements are needed in future campaigns. SOA from biomass burning sources, although not dominant in the city, remains poorly characterized and appears to be underpredicted by traditional models.

Jimenez, Jose-Luis; Schauer, James J.; Molina, Luisa T.; MILAGRO Pm Team

2010-05-01

215

URSSA, the Undergraduate Research Student Self-Assessment: A Tool for Assessing Student Outcomes of Undergraduate Research  

NASA Astrophysics Data System (ADS)

Evidence-based thinking is essential both to science and to the development of effective educational programs. Thus assessment of student learning—gathering evidence about the nature and depth of students’ learning gains, and about how they arise—is a centerpiece of any effective undergraduate research (UR) program. Assessment data can be used to monitor progress, to diagnose problems, to strengthen program designs, and to report both good outcomes and strategies to improve them to institutional and financial stakeholders in UR programs. While the positive impact of UR on students’ educational, personal and professional development has long been a matter of faith, only recently have researchers and evaluators developed an empirical basis by which to identify and explain these outcomes. Based on this growing body of evidence, URSSA, the Undergraduate Research Student Self-Assessment, is a survey tool that departments and programs can use to assess student outcomes of UR. URSSA focuses on what students learn from their UR experience, rather than whether they liked it. Both multiple-choice and open-ended items focus on students’ gains from UR, including: (1) skills such as lab work and communication; (2) conceptual knowledge and linkages among ideas in their field and with other fields; (3) deepened understanding of the intellectual and practical work of science; (4) growth in confidence and adoption of the identity of scientist; (5) preparation for a career or graduate school in science; and (6) greater clarity in understanding what career or educational path they might wish to pursue. Other items probe students’ participation in important activities that have been shown to lead to these gains; and a set of optional items can be included to probe specific program features that may supplement UR (e.g. field trips, career seminars, housing arrangements). The poster will describe URSSA's content, development, validation, and use. For more information about URSSA and how to use it, visit our web site.

Laursen, S. L.; Hunter, A.; Weston, T.; Thiry, H.

2009-12-01

216

On the use of EEG or MEG brain imaging tools in neuromarketing research.  

PubMed

Here we present an overview of some published papers of interest for the marketing research employing electroencephalogram (EEG) and magnetoencephalogram (MEG) methods. The interest for these methodologies relies in their high-temporal resolution as opposed to the investigation of such problem with the functional Magnetic Resonance Imaging (fMRI) methodology, also largely used in the marketing research. In addition, EEG and MEG technologies have greatly improved their spatial resolution in the last decades with the introduction of advanced signal processing methodologies. By presenting data gathered through MEG and high resolution EEG we will show which kind of information it is possible to gather with these methodologies while the persons are watching marketing relevant stimuli. Such information will be related to the memorization and pleasantness related to such stimuli. We noted that temporal and frequency patterns of brain signals are able to provide possible descriptors conveying information about the cognitive and emotional processes in subjects observing commercial advertisements. These information could be unobtainable through common tools used in standard marketing research. We also show an example of how an EEG methodology could be used to analyze cultural differences between fruition of video commercials of carbonated beverages in Western and Eastern countries. PMID:21960996

Vecchiato, Giovanni; Astolfi, Laura; De Vico Fallani, Fabrizio; Toppi, Jlenia; Aloise, Fabio; Bez, Francesco; Wei, Daming; Kong, Wanzeng; Dai, Jounging; Cincotti, Febo; Mattia, Donatella; Babiloni, Fabio

2011-01-01

217

On the Use of EEG or MEG Brain Imaging Tools in Neuromarketing Research  

PubMed Central

Here we present an overview of some published papers of interest for the marketing research employing electroencephalogram (EEG) and magnetoencephalogram (MEG) methods. The interest for these methodologies relies in their high-temporal resolution as opposed to the investigation of such problem with the functional Magnetic Resonance Imaging (fMRI) methodology, also largely used in the marketing research. In addition, EEG and MEG technologies have greatly improved their spatial resolution in the last decades with the introduction of advanced signal processing methodologies. By presenting data gathered through MEG and high resolution EEG we will show which kind of information it is possible to gather with these methodologies while the persons are watching marketing relevant stimuli. Such information will be related to the memorization and pleasantness related to such stimuli. We noted that temporal and frequency patterns of brain signals are able to provide possible descriptors conveying information about the cognitive and emotional processes in subjects observing commercial advertisements. These information could be unobtainable through common tools used in standard marketing research. We also show an example of how an EEG methodology could be used to analyze cultural differences between fruition of video commercials of carbonated beverages in Western and Eastern countries. PMID:21960996

Vecchiato, Giovanni; Astolfi, Laura; De Vico Fallani, Fabrizio; Toppi, Jlenia; Aloise, Fabio; Bez, Francesco; Wei, Daming; Kong, Wanzeng; Dai, Jounging; Cincotti, Febo; Mattia, Donatella; Babiloni, Fabio

2011-01-01

218

A kind of new ToolBus model research and implementation  

Microsoft Academic Search

Nowadays, software architecture of CASE (Computer Aided Software Engineering) environments is evolving from layered structure to bus structure. This bus structure can greatly simplify the interconnection structure among tools and facilitate the construction of distributed CASE environments. In this paper, from the viewpoint that tool integration facilities are separated from tool logic processing function, a pure model of ToolBus first

Bing Guo; Yan Shen; Jun Xie; Yong Wang; Guang-Ze Xiong

2004-01-01

219

A Research on Intelligent Modular Machine Tool Design System Based on KBE  

Microsoft Academic Search

As an effort to solve problems occurring in the current modular machine tool design, KBE technology is introduced into the field. The combination of modular machine tool design and KBE strengthens the inheritance and reuse of design knowledge, achieves an intelligent design for general machine tools and provides a reliable technical support for modular machine tool design. The components of

Linzhen Zhou; Defang Liu

2012-01-01

220

Single Molecule Analysis Research Tool (SMART): An Integrated Approach for Analyzing Single Molecule Data  

PubMed Central

Single molecule studies have expanded rapidly over the past decade and have the ability to provide an unprecedented level of understanding of biological systems. A common challenge upon introduction of novel, data-rich approaches is the management, processing, and analysis of the complex data sets that are generated. We provide a standardized approach for analyzing these data in the freely available software package SMART: Single Molecule Analysis Research Tool. SMART provides a format for organizing and easily accessing single molecule data, a general hidden Markov modeling algorithm for fitting an array of possible models specified by the user, a standardized data structure and graphical user interfaces to streamline the analysis and visualization of data. This approach guides experimental design, facilitating acquisition of the maximal information from single molecule experiments. SMART also provides a standardized format to allow dissemination of single molecule data and transparency in the analysis of reported data. PMID:22363412

Mabuchi, Hideo; Herschlag, Daniel

2012-01-01

221

Human Pluripotent Stem Cell-Derived Cardiomyocytes as Research and Therapeutic Tools  

PubMed Central

Human pluripotent stem cells (hPSCs), namely, embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), with their ability of indefinite self-renewal and capability to differentiate into cell types derivatives of all three germ layers, represent a powerful research tool in developmental biology, for drug screening, disease modelling, and potentially cell replacement therapy. Efficient differentiation protocols that would result in the cell type of our interest are needed for maximal exploitation of these cells. In the present work, we aim at focusing on the protocols for differentiation of hPSCs into functional cardiomyocytes in vitro as well as achievements in the heart disease modelling and drug testing on the patient-specific iPSC-derived cardiomyocytes (iPSC-CMs). PMID:24800237

Pesl, Martin; Lacampagne, Alain; Dvorak, Petr; Rotrekl, Vladimir; Meli, Albano C.

2014-01-01

222

The Right Tools for the Job: The Challenges of Theory and Method in Geoscience Education Research  

NASA Astrophysics Data System (ADS)

As geoscience education has matured as a research field over the last decade, workers in this area have been challenged to adapt methodologies and theoretical approaches to study design and data collection. These techniques are as diverse as the earth sciences themselves, and researchers have drawn on established methods and traditions from science education research, social science research, and the cognitive and learning sciences. While the diversity of methodological and theoretical approaches is powerful, the challenge is to ground geoscience education research in rigorous methodologies that are appropriate for the epistemological and functional realities of the content area and the environment in which the research is conducted. The issue of theory is the first hurdle. After techniques are proven, earth scientists typically need not worry much about the theoretical value or theory-laden nature of measurements they make in the field or laboratory. As an example, a field geologist does not question the validity of the gravitational field that levels the spirit level within a Brunton compass. However, in earth science education research, these issues are magnified because a theoretical approach to a study affects what is admitted as data and the weight that can be given to conclusions. Not only must one be concerned about the validity of measurements and observations, but also the value of this information from an epistemological standpoint. The assigning of meaning to student gestures, utterances, writing and actions all carries theoretical implications. For example, working with geologists learning or working in the field, purely experimental research designs are very difficult, and the majority of the work must be conducted in a naturalistic environment. In fact dealing with time pressure, distractions, and complexity of a field environment is part of intellectual backdrop for field geology that separates experts from novices and advanced students from beginners. Thus researchers must embrace the uncontrolled nature of the setting, the qualitative nature of the data collected, and the researcher's role in interpreting geologically appropriate actions as evidence of successful problem solving and investigation. Working to understand the role of diversity and culture in the geosciences also involves a wide array of theory, from affective issues through culturally and linguistically-influenced cognition, through gender, self-efficacy, and many other areas of inquiry. Research in understanding spatial skills draws heavily on techniques from cognition research but also must involve the field-specific knowledge of geoscientists to infuse these techniques with exemplars, a catalog of meaningful actions by students, and an understanding of how to recognize success. These examples illustrate briefly the wide array of tools from other fields that is being brought to bear to advance rigorous geoscience education research. We will illustrate a few of these and the insights we have gained, and the power of theory and method from other fields to enlighten us as we attempt to educate a broader array of earth scientists.

Riggs, E. M.

2011-12-01

223

An informatics supported web-based data annotation and query tool to expedite translational research for head and neck malignancies  

PubMed Central

Background The Specialized Program of Research Excellence (SPORE) in Head and Neck Cancer neoplasm virtual biorepository is a bioinformatics-supported system to incorporate data from various clinical, pathological, and molecular systems into a single architecture based on a set of common data elements (CDEs) that provides semantic and syntactic interoperability of data sets. Results The various components of this annotation tool include the Development of Common Data Elements (CDEs) that are derived from College of American Pathologists (CAP) Checklist and North American Association of Central Cancer Registries (NAACR) standards. The Data Entry Tool is a portable and flexible Oracle-based data entry device, which is an easily mastered web-based tool. The Data Query Tool helps investigators and researchers to search de-identified information within the warehouse/resource through a "point and click" interface, thus enabling only the selected data elements to be essentially copied into a data mart using a multi dimensional model from the warehouse's relational structure. The SPORE Head and Neck Neoplasm Database contains multimodal datasets that are accessible to investigators via an easy to use query tool. The database currently holds 6553 cases and 10607 tumor accessions. Among these, there are 965 metastatic, 4227 primary, 1369 recurrent, and 483 new primary cases. The data disclosure is strictly regulated by user's authorization. Conclusion The SPORE Head and Neck Neoplasm Virtual Biorepository is a robust translational biomedical informatics tool that can facilitate basic science, clinical, and translational research. The Data Query Tool acts as a central source providing a mechanism for researchers to efficiently find clinically annotated datasets and biospecimens that are relevant to their research areas. The tool protects patient privacy by revealing only de-identified data in accordance with regulations and approvals of the IRB and scientific review committee. PMID:19912644

2009-01-01

224

Journal of Coastal Research 22 5 13001304 West Palm Beach, Florida September 2006 Fractal Analysis of Maine's Glaciated Shoreline Tests  

E-print Network

Journal of Coastal Research 22 5 1300­1304 West Palm Beach, Florida September 2006 Fractal Analysis(5), 1300­1304. West Palm Beach (Florida), ISSN 0749-0208. Average fractal dimensions (D) are calculated

Perfect, Ed

225

Development of Complexity Science and Technology Tools for NextGen Airspace Research and Applications  

NASA Technical Reports Server (NTRS)

The objective of this research by NextGen AeroSciences, LLC is twofold: 1) to deliver an initial "toolbox" of algorithms, agent-based structures, and method descriptions for introducing trajectory agency as a methodology for simulating and analyzing airspace states, including bulk properties of large numbers of heterogeneous 4D aircraft trajectories in a test airspace -- while maintaining or increasing system safety; and 2) to use these tools in a test airspace to identify possible phase transition structure to predict when an airspace will approach the limits of its capacity. These 4D trajectories continuously replan their paths in the presence of noise and uncertainty while optimizing performance measures and performing conflict detection and resolution. In this approach, trajectories are represented as extended objects endowed with pseudopotential, maintaining time and fuel-efficient paths by bending just enough to accommodate separation while remaining inside of performance envelopes. This trajectory-centric approach differs from previous aircraft-centric distributed approaches to deconfliction. The results of this project are the following: 1) we delivered a toolbox of algorithms, agent-based structures and method descriptions as pseudocode; and 2) we corroborated the existence of phase transition structure in simulation with the addition of "early warning" detected prior to "full" airspace. This research suggests that airspace "fullness" can be anticipated and remedied before the airspace becomes unsafe.

Holmes, Bruce J.; Sawhill, Bruce K.; Herriot, James; Seehart, Ken; Zellweger, Dres; Shay, Rick

2012-01-01

226

A Tropical Marine Microbial Natural Products Geobibliography as an Example of Desktop Exploration of Current Research Using Web Visualisation Tools  

PubMed Central

Microbial marine biodiscovery is a recent scientific endeavour developing at a time when information and other technologies are also undergoing great technical strides. Global visualisation of datasets is now becoming available to the world through powerful and readily available software such as Worldwind™, ArcGIS Explorer™ and Google Earth™. Overlaying custom information upon these tools is within the hands of every scientist and more and more scientific organisations are making data available that can also be integrated into these global visualisation tools. The integrated global view that these tools enable provides a powerful desktop exploration tool. Here we demonstrate the value of this approach to marine microbial biodiscovery by developing a geobibliography that incorporates citations on tropical and near-tropical marine microbial natural products research with Google Earth™ and additional ancillary global data sets. The tools and software used are all readily available and the reader is able to use and install the material described in this article. PMID:19172194

Mukherjee, Joydeep; Llewellyn, Lyndon E; Evans-Illidge, Elizabeth A

2008-01-01

227

X-15s, HL-10, M2-F1, and M2-F2 Lifting Body research aircraft in main NASA hangar  

NASA Technical Reports Server (NTRS)

Hangar 4802 at the NASA Flight Research Center in 1966. Aircraft on left include (left to right): HL-10, M2-F2, M2-F1, F-4A, F5D-1, F-104 (barely visible) and C-47. Aircraft on the right side (left to right) include: X-15-1 (56-6670), X-15-3 (56-6672), and X-15-2 (56-6671). Hangar 4802 had been the main hangar at the Flight Research Center (FRC--now the Dryden Flight Research Center, Edwards, CA) and before that, the High-Speed Flight Station, since 1954. During 1966, the two main flight research projects at the FRC were the lifting bodies (including the M2-F1, M2-F2, and HL-10) and the X-15.

1966-01-01

228

Adventures in the microlensing cloud: Large datasets, eResearch tools, and GPUs  

NASA Astrophysics Data System (ADS)

As astronomy enters the petascale data era, astronomers are faced with new challenges relating to storage, access and management of data. A shift from the traditional approach of combining data and analysis at the desktop to the use of remote services, pushing the computation to the data, is now underway. In the field of cosmological gravitational microlensing, future synoptic all-sky surveys are expected to bring the number of multiply imaged quasars from the few tens that are currently known to a few thousands. This inflow of observational data, together with computationally demanding theoretical modeling via the production of microlensing magnification maps, requires a new approach. We present our technical solutions to supporting the GPU-Enabled, High Resolution cosmological MicroLensing parameter survey (GERLUMPH). This extensive dataset for cosmological microlensing modeling comprises over 70 000 individual magnification maps and ˜106 related results. We describe our approaches to hosting, organizing, and serving ˜30 TB of data and metadata products. We present a set of online analysis tools developed with PHP, JavaScript and WebGL to support access and analysis of GELRUMPH data in a Web browser. We discuss our use of graphics processing units (GPUs) to accelerate data production, and we release the core of the GPU-D direct inverse ray-shooting code (Thompson et al., 2010, 2014) used to generate the magnification maps. All of the GERLUMPH data and tools are available online from http://gerlumph.swin.edu.au. This project made use of gSTAR, the GPU Supercomputer for Theoretical Astrophysical Research.

Vernardos, G.; Fluke, C. J.

2014-10-01

229

A Microsoft Excel interface for rhyolite-MELTS: a tool for research and teaching of magma properties and evolution  

NASA Astrophysics Data System (ADS)

The thermodynamic modeling software MELTS (and its derivatives) is a powerful and much utilized tool for investigating crystallization and melting in natural magmatic systems. Rhyolite-MELTS (Gualda et al. 2012, J. Petrol. 53:875-890) is a recent recalibration of MELTS aimed at better capturing the evolution of magmas present in the upper crust (up to ~400 MPa pressure). Currently, most users of rhyolite-MELTS rely on a graphical user interface (GUI), which can be run on UNIX/LINUX and Mac OS X computers. While the interface is powerful and flexible, it can be somewhat cumbersome for the novice and the output is in the form of text files that need to be processed offline. This situation is probably the main reason why MELTS - despite great potential - has not been used more frequently for teaching purposes. We are currently developing an alternative GUI for rhyolite-MELTS using web services consumed by a VBA backend in Microsoft Excel©. The goal is to create a much more interactive tool, that is easy to use that can be made available to a widespread audience, and that will be useful for both research and teaching. The interface is contained within a macro-enabled workbook, which includes editable cells where the user can insert the model input information. Interface buttons initiate computations that are executed on a central server at OFM Research in Seattle (WA). Results of simple calculations are shown immediately within the interface itself. For instance, a user can very rapidly determine the temperature at which a magma of a given composition is completely molten (i.e. find the liquidus); or determine which phases are present, in what abundances, their compositions, and their physical properties (e.g. density, viscosity) at any given combination of temperature, pressure and oxygen fugacity. We expect that using the interface in this mode will greatly facilitate building intuition about magmas and their properties. It is also possible to combine a sequence of calculations into an evolutionary path. The user can input starting and ending temperatures and pressures, temperature and pressure steps, and the prevailing oxidation conditions, and the program will perform the calculations showing the magma properties at every step; at the conclusion of the calculations, a series of data sheets and diagrams are created in a separate workbook, which can be saved independently of the interface. Additionally, the user can specify a grid of temperatures and pressures and calculate a phase diagram showing the conditions at which different phases are present. We envision a host of exercises that can be tackled by students of all levels exploring the varied evolution of natural magma compositions. The main advantages of this new platform are that it is simple to use and flexible. Workbooks can be created for specific exercises, facilitating their use in classroom assignments. The Excel GUI interface is built on a popular platform, which is widely available, requires no installation, and is distributed for free from melts.ofm-research.org. The main drawback is that operation of the workbook requires an internet connection. The web services used are currently only accessible by Excel 2010 and 2013 for Windows.

Gualda, G. A.; Ghiorso, M. S.

2013-12-01

230

Research on the information extraction technology of cutting tool based on open CASCADE  

Microsoft Academic Search

In order to generate the tool geometry data model of STEP data structure in keeping with the ISO14649 protocol, achieve the tool geometry simulation of NC machining simulation process, the paper analyzes STEP standard and its file structure, develop the display software which can read and display the STEP format file of tool cutter based on open source Open CASCADE

Xuebin Liu; Wei Zhao; Chongning Li; Suchang Ma

2012-01-01

231

Fishery management as a governance network: Examples from the Gulf of Maine and the potential for communication network analysis research  

E-print Network

for communication network analysis research in fisheries Troy W. Hartley Ã? Virginia Institute of Marine Sciences management Governance network Communication network analysis a b s t r a c t It has been suggested that the fisheries management process with multiple, informed stakeholders and socio-economic, political

Newman, Michael C.

232

A Comparison of Student Knowledge and Attitude toward Research: Are Main Campus Students Different from Those in a Hybrid Environment?  

ERIC Educational Resources Information Center

The trend toward the use of distance education in teaching social work students has been rapidly growing over the past two decades. A constant issue of concern is related to student outcomes. This paper reports on a longitudinal quasi-experimental study assessing the differential knowledge and attitude toward research between social work students…

Buchanan, Rachel L.; Mathews, Deborah A.

2013-01-01

233

MAINE AQUIFERS  

EPA Science Inventory

AQFRS24 contains polygons of significant aquifers in Maine (glacial deposits that are a significant ground water resource) mapped at a scale 1:24,000. This statewide coverage was derived from aquifer boundaries delineated and digitized by the Maine Geological Survey from data com...

234

Electric Field Encephalography as a Tool for Functional Brain Research: A Modeling Study  

PubMed Central

We introduce the notion of Electric Field Encephalography (EFEG) based on measuring electric fields of the brain and demonstrate, using computer modeling, that given the appropriate electric field sensors this technique may have significant advantages over the current EEG technique. Unlike EEG, EFEG can be used to measure brain activity in a contactless and reference-free manner at significant distances from the head surface. Principal component analysis using simulated cortical sources demonstrated that electric field sensors positioned 3 cm away from the scalp and characterized by the same signal-to-noise ratio as EEG sensors provided the same number of uncorrelated signals as scalp EEG. When positioned on the scalp, EFEG sensors provided 2–3 times more uncorrelated signals. This significant increase in the number of uncorrelated signals can be used for more accurate assessment of brain states for non-invasive brain-computer interfaces and neurofeedback applications. It also may lead to major improvements in source localization precision. Source localization simulations for the spherical and Boundary Element Method (BEM) head models demonstrated that the localization errors are reduced two-fold when using electric fields instead of electric potentials. We have identified several techniques that could be adapted for the measurement of the electric field vector required for EFEG and anticipate that this study will stimulate new experimental approaches to utilize this new tool for functional brain research. PMID:23844066

Petrov, Yury; Sridhar, Srinivas

2013-01-01

235

GERLUMPH Data Release 1: High-resolution Cosmological Microlensing Magnification Maps and eResearch Tools  

NASA Astrophysics Data System (ADS)

As synoptic all-sky surveys begin to discover new multiply lensed quasars, the flow of data will enable statistical cosmological microlensing studies of sufficient size to constrain quasar accretion disk and supermassive black hole properties. In preparation for this new era, we are undertaking the GPU-Enabled, High Resolution cosmological MicroLensing parameter survey (GERLUMPH). We present here the GERLUMPH Data Release 1, which consists of 12,342 high resolution cosmological microlensing magnification maps and provides the first uniform coverage of the convergence, shear, and smooth matter fraction parameter space. We use these maps to perform a comprehensive numerical investigation of the mass-sheet degeneracy, finding excellent agreement with its predictions. We study the effect of smooth matter on microlensing induced magnification fluctuations. In particular, in the minima and saddle-point regions, fluctuations are enhanced only along the critical line, while in the maxima region they are always enhanced for high smooth matter fractions (?0.9). We describe our approach to data management, including the use of an SQL database with a Web interface for data access and online analysis, obviating the need for individuals to download large volumes of data. In combination with existing observational databases and online applications, the GERLUMPH archive represents a fundamental component of a new microlensing eResearch cloud. Our maps and tools are publicly available at http://gerlumph.swin.edu.au/.

Vernardos, G.; Fluke, C. J.; Bate, N. F.; Croton, D.

2014-03-01

236

Spontaneous versus trained numerical abilities. A comparison between the two main tools to study numerical competence in non-human animals.  

PubMed

A large body of experimental evidence shows that animals as diverse as mammals, birds, and fish are capable of processing numerical information. Considerable differences have been reported in some cases among species and a wide debate currently surrounds the issue of whether all vertebrates share the same numerical systems or not. Part of the problem is due to the fact that these studies often use different methods, a circumstance that potentially introduces confounding factors in a comparative analysis. In most studies, two main methodological approaches have been used: spontaneous choice tests and training procedures. The former approach consists of presenting to the subjects two groups of biologically-relevant stimuli (e.g., food items or social companions) differing in numerosity with the assumption that if they are able to discriminate between the two quantities, they are expected to spontaneously select the larger/smaller quantity. In the latter approach, subjects undergo extensive training in which some neutral stimuli (e.g., a quantity of dots) are associated with a reward and the capacity to learn a numerical rule is taken as evidence of numerical abilities. We review the literature on this topic, highlighting the relevance, and potential weaknesses in controlling confounding factors obtained with either approach. PMID:24793399

Agrillo, Christian; Bisazza, Angelo

2014-08-30

237

MARSTHERM: A Web-based System Providing Thermophysical Analysis Tools for Mars Research  

NASA Astrophysics Data System (ADS)

We introduce MARSTHERM, a web-based system that will allow researchers access to a standard numerical thermal model of the Martian near-surface and atmosphere. In addition, the system will provide tools for the derivation, mapping, and analysis of apparent thermal inertia from temperature observations by the Mars Global Surveyor Thermal Emission Spectrometer (TES) and the Mars Odyssey Thermal Emission Imaging System (THEMIS). Adjustable parameters for the thermal model include thermal inertia, albedo, surface pressure, surface emissivity, atmospheric dust opacity, latitude, surface slope angle and azimuth, season (solar longitude), and time steps for calculations and output. The model computes diurnal surface and brightness temperatures for either a single day or a full Mars year. Output options include text files and plots of seasonal and diurnal surface, brightness, and atmospheric temperatures. The tools for the derivation and mapping of apparent thermal inertia from spacecraft data are project-based, wherein the user provides an area of interest (AOI) by specifying latitude and longitude ranges. The system will then extract results within the AOI from prior global mapping of elevation (from the Mars Orbiter Laser Altimeter, for calculating surface pressure), TES annual albedo, and TES seasonal and annual-mean 2AM and 2PM apparent thermal inertia (Putzig and Mellon, 2007, Icarus 191, 68-94). In addition, a history of TES dust opacity within the AOI is computed. For each project, users may then provide a list of THEMIS images to process for apparent thermal inertia, optionally overriding the TES-derived dust opacity with a fixed value. Output from the THEMIS derivation process includes thumbnail and context images, GeoTIFF raster data, and HDF5 files containing arrays of input and output data (radiance, brightness temperature, apparent thermal inertia, elevation, quality flag, latitude, and longitude) and ancillary information. As a demonstration of capabilities, we will present results from a thermophysical study of Gale Crater (Barratt and Putzig, 2013, EPSC abstract 613), for which TES and THEMIS mapping has been carried out during system development. Public access to the MARSTHERM system will be provided in conjunction with the 2013 AGU Fall Meeting and will feature the numerical thermal model and thermal-inertia derivation algorithm developed by Mellon et al. (2000, Icarus 148, 437-455) as modified by Putzig and Mellon (2007, Icarus 191, 68-94). Updates to the thermal model and derivation algorithm that include a more sophisticated representation of the atmosphere and a layered subsurface are presently in development, and these will be incorporated into the system when they are available. Other planned enhancements include tools for modeling temperatures from horizontal mixtures of materials and slope facets, for comparing heterogeneity modeling results to TES and THEMIS results, and for mosaicking THEMIS images.

Putzig, N. E.; Barratt, E. M.; Mellon, M. T.; Michaels, T. I.

2013-12-01

238

Students' Perceptions of the Effectiveness of the World Wide Web as a Research and Teaching Tool in Science Learning.  

ERIC Educational Resources Information Center

Investigates the use of the World Wide Web (WWW) as a research and teaching tool in promoting self-directed learning groups of 15-year-old students. Discusses the perceptions of students of the effectiveness of the WWW in assisting them with the construction of knowledge on photosynthesis and respiration. (Contains 33 references.) (Author/YDS)

Ng, Wan; Gunstone, Richard

2002-01-01

239

Collaborative Research: Carbon Flux Through the Twilight Zone -New Tools to Measure Change A-1 WHOI Proposal No. CH11471  

E-print Network

Collaborative Research: Carbon Flux Through the Twilight Zone - New Tools to Measure Change A-1 in the Twilight Zone (i.e. mesopelagic). It is within the poorly understood Twilight Zone where changes in C collection and swimmer free samples are needed, as envisioned for our new design- the Twilight Zone EXplorer

Buesseler, Ken

240

Taxonomy shifts up a gear: New publishing tools to accelerate biodiversity research i Taxonomy shifts up a gear  

E-print Network

Taxonomy shifts up a gear: New publishing tools to accelerate biodiversity research i Taxonomy the publishing impediment in order to move taxonomy "from a cottage industry into a production line" (Lane et al the landscape of semantic tagging and text enhancements in taxonomy. It describes how the content

Erwin, Terry

241

TOOLS FOR DETERMINING SUSTAINABLE WASTE MANAGEMENT THROUGH APPLICATION OF LIFE-CYCLE ASSESSMENT: UPDATE ON U.S. RESEARCH  

EPA Science Inventory

The paper is an update on U.S. research to develop tools and information for evaluating integrated solid waste management strategies. In the past, waste management systems consisted primarily of waste collection and disposal at a local landfill. Today's municipal solid waste ma...

242

Students' Perceptions of the Effectiveness of the World Wide Web as a Research and Teaching Tool in Science Learning  

Microsoft Academic Search

Students often make little linkage from lesson to lesson on what they learn in the regular classroom. Having them take responsibility for what they are learning is one way of having them think and connect these thoughts together. This qualitative study looks at the use of the World Wide Web (WWW) as a research and teaching tool in promoting self-directed

Wan Ng; Richard Gunstone

2002-01-01

243

Conceptual Tools for Research on Race and Social Problems: An Overview of Dynamic Theory and Model Development  

Microsoft Academic Search

Although interpersonal, group processes and inter-group relationships are dynamic phenomena, researchers have studied these phenomena in a static manner. This article provides an overview of system dynamic modeling to bring greater attention to the importance of dynamic theoretical formulations and presents important concepts and tools that can facilitate movement in this direction. Important concepts for theory development are delineated, and

Von E. Nebbitt; Sabrina W. Tyuse; Michael G. Vaughn; Brian E. Perron

2010-01-01

244

UVM Scientists Identify Eco-Friendly Tool for Fighting Wheat Blight AGRICULTURAL RESEARCH (01.10.07)  

E-print Network

an unpleasant taste. Moreover, seeds from an infected crop won't germinate the following year. Minimal Sunn pestUVM Scientists Identify Eco-Friendly Tool for Fighting Wheat Blight AGRICULTURAL RESEARCH (01 of threat in those war-torn countries: a destructive wheat blight found in many parts of the Middle East

Vermont, University of

245

E-LEARNING READINESS INDEX RESEARCH TOOLS BERBASIS WEB SEBAGAI ALAT BANTU UNTUK EVALUASI IMPLEMENTASI E-LEARNING  

E-print Network

E-LEARNING READINESS INDEX RESEARCH TOOLS BERBASIS WEB SEBAGAI ALAT BANTU UNTUK EVALUASI IMPLEMENTASI E-LEARNING Ridho Rahmadi, Yudi Prayudi Jurusan Teknik Informatika, Fakultas Teknologi Industri.rahmadi@staff.uii.ac.id ABSTRAKS In order to understand how far the implementation of e-learning in an institution, we need

Hammerton, James

246

Research and Teaching: Photovoice as a Pedagogical Tool--Student Engagement in Undergraduate Introductory Chemistry for Nonscience Majors  

ERIC Educational Resources Information Center

This study explores the use of Photovoice as a pedagogical tool in two introductory undergraduate chemistry courses for nonscience majors. Photovoice, historically linked to participatory action research, is a qualitative mode of inquiry in which the perspectives provided in narratives and pictures are generally personal, subjective, and unique.…

Stroud, Mary W.

2014-01-01

247

CORE SIM: A multi-purpose neutronic tool for research and education Christophe Demazire  

E-print Network

calculations Dynamic calculations Neutron noise Model development Benchmarking a b s t r a c t This paper deals with the development, validation, and demonstration of an innovative neutronic tool. The novelty of the tool resides neutron source can be studied, and static and dynamic cases in the frequency domain (i.e. for stationary

Demazière, Christophe

248

The virtual supermarket: an innovative research tool to study consumer food purchasing behaviour. — Measures of the Food Environment  

Cancer.gov

Skip to Main Content at the National Institutes of Health | www.cancer.gov Print Page E-mail Page Search: Please wait while this form is being loaded.... Home Browse by Resource Type Browse by Area of Research Research Networks Funding Information About

249

The Main Pillar: Assessment of Space Weather Observational Asset Performance Supporting Nowcasting, Forecasting and Research to Operations  

NASA Technical Reports Server (NTRS)

Space weather forecasting critically depends upon availability of timely and reliable observational data. It is therefore particularly important to understand how existing and newly planned observational assets perform during periods of severe space weather. Extreme space weather creates challenging conditions under which instrumentation and spacecraft may be impeded or in which parameters reach values that are outside the nominal observational range. This paper analyzes existing and upcoming observational capabilities for forecasting, and discusses how the findings may impact space weather research and its transition to operations. A single limitation to the assessment is lack of information provided to us on radiation monitor performance, which caused us not to fully assess (i.e., not assess short term) radiation storm forecasting. The assessment finds that at least two widely spaced coronagraphs including L4 would provide reliability for Earth-bound CMEs. Furthermore, all magnetic field measurements assessed fully meet requirements. However, with current or even with near term new assets in place, in the worst-case scenario there could be a near-complete lack of key near-real-time solar wind plasma data of severe disturbances heading toward and impacting Earth's magnetosphere. Models that attempt to simulate the effects of these disturbances in near real time or with archival data require solar wind plasma observations as input. Moreover, the study finds that near-future observational assets will be less capable of advancing the understanding of extreme geomagnetic disturbances at Earth, which might make the resulting space weather models unsuitable for transition to operations.

Posner, Arik; Hesse, Michael; SaintCyr, Chris

2014-01-01

250

MAINE WOODLOTS  

EPA Science Inventory

MEOWN250 describes industrial, non-industrial, and public woodlot ownership in Maine at 1:250,000 scale. Industrial owners are those having at least one primary wood processing facility. Non-industrial owners are those with no primary wood processing facility. Public ownership...

251

Unmanned Aerial Systems as Versatile Tools for Atmospheric and Environmental Research  

NASA Astrophysics Data System (ADS)

Unmanned Aerial Systems (UASs) are increasingly recognized as versatile tools for different earth-sciences applications providing chiefly a link between in-situ ground based measurements and satellite remote sensing observations. Based on the Autonomous Flying Platforms for Atmospheric and Earth Surface Observations project (APAESO) of the Energy, Environment and Water Research Center (EEWRC) at the Cyprus Institute (APAESO is co-financed by the European Development Fund and the Republic of Cyprus through the Cyprus Research Promotion Foundation: ??? ???????/?????/0308/09), we have acquired four CRUISERS (ET-Air, Slovakia) as UAS platforms and a substantial range of scientific instruments to be employed on these platforms. The APAESO platforms are aimed at the dual purpose of carrying out atmospheric and earth-surface observations in the (Eastern) Mediterranean They will enable 3D measurements for determining physical, chemical and radiative atmospheric properties, aerosol and dust concentrations and atmospheric dynamics as well as 2D investigations into land management practices, vegetation and agricultural mapping, contaminant detection and the monitoring and assessment of hydrological parameters and processes of a given region at high spatial resolution. Currently, we are building up an Unmanned Airplane Facility at CyI. In the process of reaching full operational capacity, we have initiated and carried out first test missions involving highly specialized and specifically adapted instrumentation for atmospheric investigations. The first scientific mission involves the employment of a DOAS-system (Differential Optical Absorption Spectroscopy) in cooperation with colleagues from Heidelberg and Mainz, Germany and has been successfully completed. More recently, we started work on a new collaborative project aimed at measuring vertical profiles of aerosols in the Eastern Mediterranean. The project involves colleagues from the University of Frankfurt, Germany as well as from the University of Tel Aviv and the Weizmann Institute, both in Israel. For this project, a specially designed multi-stage electrostatic aerosol collector is being placed on one of the APAESO UAS. Simultaneously, atmospheric aerosols size and concentrations will be measured with an optical aerosol spectrometer, mounted on the same platform. The collected samples will be divided into two parts for analysis in both the University of Frankfurt and the Weizmann Institute

Lange, Manfred; Argyrides, Marios; Ioannou, Stelios; Keleshis, Christos; Levin, Zev

2013-04-01

252

[Clinical psychopathological research on late-onset schizophrenia--mainly patients with schizophrenia from a hospital psychiatric ward].  

PubMed

In the field of clinical psychiatry, cases of late-onset schizophrenia are often observed in the population of 40 years or older. Female patients seem to significantly predominate those diagnosed with late-onset schizophrenia. Generally, paranoid delusions of reference with family members, neighbors, and friends are observed as clinical features of such late-onset schizophrenia conditions. Medical treatment for such a condition is often effective and considered to improve the prognosis. The authors conducted clinical research at Jichi Medical University Hospital psychiatric ward involving 38 late-onset schizophrenia patients (7 males; 31 females) diagnosed over the age of 40 using DSM-IV-TR diagnostic criteria. Subjects were selected from 316 schizophrenia patients (164 males; 152 females) admitted to the hospital for schizophrenia treatment at some time during the 13 years from April 1, 1993 to March 31, 2006. Also, another 14 late-onset schizophrenia patients diagnosed over the age of 40 (1 male; 13 females), with additional investigation, were selected from 130 cases (50 males; 80 females) treated in related facilities at some time during the 2 years from April 1, 2004 to March 31, 2006. The investigation revealed the following results: (1) Cases showing an onset after the age of 40 comprised 12% of the total population. Female cases comprised 20.4%, being significantly higher than that of male cases (4.3%). Within the psychiatric ward, cases showing an onset after 40 made up 10.8% of the total population. Female cases comprised 16.3%, being significantly higher than that of male cases (2.0%). (2) The paranoid type comprised 55.3% of the total population of late-onset cases, being significantly higher than in early-onset cases younger than 40 years old. A total of 55.3% of late-onset cases also showed depressive symptoms, being significantly higher than in early-onset cases. (3) For late-onset, 55.3% of patients showed an introverted premorbid character, while 15.8% of patients exhibited an extroverted premorbid character. Regarding late-onset cases, the number of introverted premorbid character cases significantly lower than in early-onset cases diagnosed at 40 years or younger; however, no significant difference was observed for the extroverted premorbid character. (4) A total of 65.8% of the population of late-onset cases were diagnosed as having psychosocial stresses as their cause. In addition, 36 % of subjects with psychosocial stress recognition had experienced a sense of loss. Of these, 66.6% of the loss experience involved separation from their family members. (5) Cases showing a successful recovery from schizophrenia comprised 55.3 % of the total population. On the other hand, cases with an unsuccessful outcome were observed in 34.2% of the total population, accounting for a relatively large portion. A total of 30.8% of subjects with an unsuccessful outcome were unmarried at the time of onset, and made up 57.1% of the late-onset population. According to the results of this investigation, late-onset schizophrenia represents about 10% of the total cases, and female cases are significantly more common than male cases. For late-onset patients, subjects' self-functions were more developed compared to those of early-onset patients, so they did not seem to clearly show early-onset symptoms during a younger period. The late-onset type has a tendency to show a better rate of successful recovery; however, there are situations where the condition reverts toward the "disorganized type", moving closer toward Kraepelin's early-onset disorganized schizophrenia. PMID:19425390

Yasuda, Manabu; Kato, Satoshi

2009-01-01

253

The Development of an Online Research Tool to Investigate Children's Social Bonds with Robots  

NASA Astrophysics Data System (ADS)

As children are increasingly exposed to robots, it is important to learn more about the social interaction and bond that may develop between robots and children. In this paper we report the development of an interactive tool to measure children's attitudes toward social robots for children ages 6-10. A first version of the KidSAR instrument was tested and a pilot study was carried out to evaluate and improve the design of the KidSAR (Children's Social Attitude toward Robots) tool. The pilot study involved a small scale field experiment assessing whether children feel more social connection with a robot in a caring role compared with a role where it needed to be taken care of. The final KidSAR tool was developed after evaluation of children's responses and observation of children using the tool.

Veenstra, Dana Nathalie; Evers, Vanessa

254

Promises and Challenges in Developing RNAi as a Research Tool and Therapy for Neurodegenerative Diseases  

Microsoft Academic Search

RNA interference (RNAi) is a recently discovered mechanism that is conserved in a wide range of eukaryotic species. Triggered by double-stranded RNA, RNAi identifies and destroys the mRNA that shares homology with the double-stranded RNA. Because of its specificity, RNAi has a high potential for being a powerful investigative and therapeutic tool. Indeed, its use as a reverse genetics tool

Xu Gang Xia; Hongxia Zhou; Zuoshang Xu

2005-01-01

255

Heavy ion microprobes: a unique tool for bystander research and other radiobiological applications  

NASA Astrophysics Data System (ADS)

The risk assessment for low doses of high linear energy transfer (LET) radiation has been challenged by a growing body of experimental evidence showing that non-irradiated bystander cells can receive signals from irradiated cells to elicit a variety of cellular responses. These may be significant for radiation protection but also for radiation therapy using heavy ions. Charged particle microbeams for radiobiological application provide a unique means to address these issues by allowing the precise irradiation of single cells with a counted numbers of ions. Here, we focus specifically on heavy ion microbeam facilities currently in use for biological purposes, describing their technical features and biological results. Typically, ion species up to argon are used for targeted biological irradiation at the vertically collimated microbeam at JAEA (Takasaki, Japan). At the SNAKE microprobe in Munich, mostly oxygen ions have been used in a horizontal focused beam line for cell targeting. At GSI (Darmstadt), a horizontal microprobe with a focused beam for defined targeting using ion species up to uranium is operational. The visualization of DNA damage response proteins relocalizing to defined sites of ion traversal has been accomplished at the three heavy ion microbeam facilities described above and is used to study mechanistic aspects of heavy ion effects. However, bystander studies have constituted the main focus of biological applications. While for cell inactivation and effects on cell cycle progression a response of non-targeted cells has been described at JAEA and GSI, respectively, in part controversial results have been obtained for the induction of DNA damage measured by double-strand formation or at the cytogenetic level. The results emphasize the influence of the cellular environment, and standardization of experimental conditions for cellular studies at different facilities as well as the investigation of bystander effects in tissue will be the aims of future research. At present, the most important conclusion of radiobiology studies at heavy ion microbeams is that bystander responses are not accentuated for increasing ionizing density radiation.

Voss, K. O.; Fournier, C.; Taucher-Scholz, G.

2008-07-01

256

Funding acknowledgement analysis: an enhanced tool to investigate research sponsorship impacts: the case of nanotechnology  

Microsoft Academic Search

There is increasing interest in assessing how sponsored research funding influences the development and trajectory of science\\u000a and technology. Traditionally, linkages between research funding and subsequent results are hard to track, often requiring\\u000a access to separate funding or performance reports released by researchers or sponsors. Tracing research sponsorship and output\\u000a linkages is even more challenging when researchers receive multiple funding

Jue Wang; Philip Shapira

2011-01-01

257

James Kidder Main Research Library  

E-print Network

. R. C., et al. (2009). Terrestrial Carbon Sequestration - Science for Enhancement and Implementation of carbon sequestration data and models. In B. J. McPherson & E. T. Sundquist (Eds.), Carbon Sequestration

258

James Kidder Main Research Library  

E-print Network

@ornl.gov Environmental Sciences Publications--Calendar Year 2007 Compiled January 11, 2008 by James Kidder Total in United States snowfall: 1948-2005. Paper presented at the 19th Conference on Climate Variability

259

Effective communication tools to engage Torres Strait Islanders in scientific research  

NASA Astrophysics Data System (ADS)

Often, research activities in Torres Strait have not delivered full benefit to Torres Strait Islanders due to a lack of consultation, ineffectual communication of research information and lack of empathy for the needs of Islander communities. As for other stakeholder groups, integration of Islanders into the research process through practical involvement in research may overcome these problems. Three case studies from research projects conducted in Torres Strait are discussed to highlight a variety of communication and engagement activities carried out by non-Indigenous researchers. How these communication and extension activities facilitate collaboration between Torres Strait Islander and non-Indigenous researchers provides insight in the importance of these activities to the relative success of research projects. The benefits for Islanders in collaborating with researchers may be: improved understanding of the research and how it contributes to natural resource management; a sense of control in future management decisions; a greater likelihood of successful self-regulatory management systems; enhanced skills; and increased employment opportunities. The potential benefits for researchers are enhanced support for research projects resulting in increased access to data and logistic support that may ultimately impact the successful completion of projects. Such an approach will require researchers to take time to develop relationships with Torres Strait Islanders, effectively involve Islanders in research on an equitable basis and be flexible. This will ultimately require funding organisations to recognise the importance of such activities in research proposals and provide support through sufficient funding to enable these activities to be carried out.

Jones, A.; Barnett, B.; Williams, A. J.; Grayson, J.; Busilacchi, S.; Duckworth, A.; Evans-Illidge, E.; Begg, G. A.; Murchie, C. D.

2008-09-01

260

Main University Entrance Main University Reception  

E-print Network

Economics Research Group School of Arts (taught programmes) Marie Jahoda School of Social Sciences (UG, PG Athletics Centre Eastern Gateway Main Reception Beldam Gallery Brunel Business School Lancaster Suite Conference Office Mary Seacole Health and Social Care (enquiries) Sports Centre St Johns Information Systems

Martin, Ralph R.

261

Linguistic validation of the Alberta Context Tool and two measures of research use, for German residential long term care  

PubMed Central

Background To study the association between organizational context and research utilization in German residential long term care (LTC), we translated three Canadian assessment instruments: the Alberta Context Tool (ACT), Estabrooks’ Kinds of Research Utilization (RU) items and the Conceptual Research Utilization Scale. Target groups for the tools were health care aides (HCAs), registered nurses (RNs), allied health professionals (AHPs), clinical specialists and care managers. Through a cognitive debriefing process, we assessed response processes validity–an initial stage of validity, necessary before more advanced validity assessment. Methods We included 39 participants (16 HCAs, 5 RNs, 7 AHPs, 5 specialists and 6 managers) from five residential LTC facilities. We created lists of questionnaire items containing problematic items plus items randomly selected from the pool of remaining items. After participants completed the questionnaires, we conducted individual semi-structured cognitive interviews using verbal probing. We asked participants to reflect on their answers for list items in detail. Participants’ answers were compared to concept maps defining the instrument concepts in detail. If at least two participants gave answers not matching concept map definitions, items were revised and re-tested with new target group participants. Results Cognitive debriefings started with HCAs. Based on the first round, we modified 4 of 58 ACT items, 1 ACT item stem and all 8 items of the RU tools. All items were understood by participants after another two rounds. We included revised HCA ACT items in the questionnaires for the other provider groups. In the RU tools for the other provider groups, we used different wording than the HCA version, as was done in the original English instruments. Only one cognitive debriefing round was needed with each of the other provider groups. Conclusion Cognitive debriefing is essential to detect and respond to problematic instrument items, particularly when translating instruments for heterogeneous, less well educated provider groups such as HCAs. Cognitive debriefing is an important step in research tool development and a vital component of establishing response process validity evidence. Publishing cognitive debriefing results helps researchers to determine potentially critical elements of the translated tools and assists with interpreting scores. PMID:24479645

2014-01-01

262

Evaluating Mastery of Biostatistics for Medical Researchers: Need for a new assessment tool  

PubMed Central

Research training has enabled academic clinicians to contribute significantly to the body of medical research literature. Biostatistics represents a critical methodological skill for such researchers, as statistical methods are increasingly a necessary part of medical research. However, there is no validated knowledge and skills assessment for graduate level biostatistics for academic medical researchers. In this paper I review graduate level statistical competencies and existing instruments intended to assess physicians’ ability to read the medical literature and for undergraduate statistics for their alignment with core competencies necessary for successful use of statistics. This analysis shows a need for a new instrument to assess biostatistical competencies for medical researchers. PMID:22212227

Enders, Felicity

2011-01-01

263

6/16/13 Researchers develop new tool to fight child porn -Times Of India articles.timesofindia.indiatimes.com/2013-06-06/computing/39787435_1_researchers-law-enforcement-personal-data 1/2  

E-print Network

6/16/13 Researchers develop new tool to fight child porn - Times Of India articles.timesofindia.indiatimes.com/2013-06-06/computing/39787435_1_researchers-law-enforcement-personal-data 1/2 Tags: Porn | Child pornography | child porn Researchers develop new tool to fight child porn ANI Jun 6, 2013, 05.31PM IST

Fung, Benjamin C. M.

264

PRE-QAPP AGREEMENT (PQA) AND ANALYTICAL METHOD CHECKLISTS (AMCS): TOOLS FOR PLANNING RESEARCH PROJECTS  

EPA Science Inventory

The Land Remediation and Pollution Control Division (LRPCD) QA Manager strives to assist LRPCD researchers in developing functional planning documents for their research projects. As part of the planning process, several pieces of information are needed, including information re...

265

SignStream: A tool for linguistic and computer vision research on visual-gestural language data  

Microsoft Academic Search

Research on recognition and generation of signed languages and the gestural component of spoken languages has been held back\\u000a by the unavailability of large-scale linguistically annotated corpora of the kind that led to significant advances in the\\u000a area of spoken language. A major obstacle has been the lack of computational tools to assist in efficient analysis and transcription\\u000a of visual

Carol Neidle; Stan Sclaroff; Vassilis Athitsos

2001-01-01

266

Of Patriots and Profits: New Tools for Keeping Academic Research in Line  

Microsoft Academic Search

How much is the federal government policing scientific research? How has this policing changed existing government-research relations within the academic research sector? The recent FBI investigation of Professor Steven Kurtz and the internationally acclaimed artists' collective Critical Art Ensemble (CAE) inspired us to take a closer look at the current administration's use and misuse of the expanded government and law

Beatriz da Costa; Claire Pentecost

2005-01-01

267

PIN: a binary instrumentation tool for computer architecture research and education  

Microsoft Academic Search

Computer architecture embraces a tremendous number of ever-changing inter-connected concepts and information, yet computer architecture education is very often static, seemingly motionless. Computer architecture is commonly taught using simple piecewise methods of explaining how the hardware performs a given task, rather than characterizing the interaction of software and hardware. Visualization tools allow students to interactively explore basic concepts in computer

Vijay Janapa Reddi; Alex Settle; Daniel A. Connors; Robert S. Cohn

2004-01-01

268

Concept to develop a software-based counter-terrorism campaign decision support tool: research note  

Microsoft Academic Search

In the public policy community, a need exists for a software program that applies leading concepts of counterterrorism (CT) analysis to systematically display, track, operationalize and update on one's computer all the decisions and processes involved in addressing all the measures required to respond to, and, if possible, resolve on-going terrorist-type insurgencies. Such a tool kit would be employed for

Joshua Sinai

2010-01-01

269

Research Notes. Archimedes: Analysis of a HyperCard Reference Tool.  

ERIC Educational Resources Information Center

Presents a study of Archimedes as a HyperCard reference tool at the University of Michigan, and compares uses to similar projects. Results from studied points (i.e., system design and use statistics) support Archimedes: the system sees more use during reference hours when a librarian is unavailable, and user time is comparable to time spent with a…

Ottaviani, J. S.

1995-01-01

270

Relating Science and Religion: An Ontology of Taxonomies and Development of a Research Tool for Identifying Individual Views  

NASA Astrophysics Data System (ADS)

Understanding how individuals view the relationship between science and religion shows promise for explaining a range of aspects of teaching and learning in science. Several taxonomies, consisting of different views by which people relate science and religion, can be found in the philosophical literature. However, most of the science education literature uses these taxonomies selectively and with limited justification, hindering comparison between existing and future studies. The first aim of this paper is therefore to provide a comprehensive review of the different taxonomies described in the literature and to organise the different views according to their similarities and differences. The second aim of the paper is to present a new research tool developed on the basis of the findings of the literature review. This tool consists of a short questionnaire allowing educational researchers to identify the different viewpoints held by pre-service teachers, undergraduates majoring in biology and school learners. We present the tool itself and demonstrate its usefulness and versatility for future science education research based on three empirical studies covering a range of geographical areas, religious backgrounds, educational levels, age groups and genders.

Yasri, Pratchayapong; Arthur, Shagufta; Smith, Mike U.; Mancy, Rebecca

2013-10-01

271

Using Animation as an Information Tool to Advance Health Research Literacy among Minority Participants  

PubMed Central

Lack of adequate consumer health information about clinical research contributes to health disparities among low health literate minority multicultural populations and requires appropriate methods for making information accessible. Enhancing understanding of health research can enable such minority multicultural consumers to make informed, active decisions about their own health and research participation. This qualitative study examines the effectiveness and acceptability of an animated video to enhance what we call health research literacy among minority multicultural populations. A team analyzed the transcripts of 58 focus groups of African Americans, Latinos, Native Hawaiians, and Filipinos in Los Angeles/Hawaii. Participants were accepting of animation and the video’s cultural appropriateness. Communicating information about health research via animation improved participants’ ability to identify personal information-gaps, engage in meaningful community-level dialogue, and ask questions about health research. PMID:24551351

George, Sheba; Moran, Erin; Duran, Nelida; Jenders, Robert A

2013-01-01

272

Using animation as an information tool to advance health research literacy among minority participants.  

PubMed

Lack of adequate consumer health information about clinical research contributes to health disparities among low health literate minority multicultural populations and requires appropriate methods for making information accessible. Enhancing understanding of health research can enable such minority multicultural consumers to make informed, active decisions about their own health and research participation. This qualitative study examines the effectiveness and acceptability of an animated video to enhance what we call health research literacy among minority multicultural populations. A team analyzed the transcripts of 58 focus groups of African Americans, Latinos, Native Hawaiians, and Filipinos in Los Angeles/Hawaii. Participants were accepting of animation and the video's cultural appropriateness. Communicating information about health research via animation improved participants' ability to identify personal information-gaps, engage in meaningful community-level dialogue, and ask questions about health research. PMID:24551351

George, Sheba; Moran, Erin; Duran, Nelida; Jenders, Robert A

2013-01-01

273

Qualitative and Quantitative Management Tools Used by Financial Officers in Public Research Universities  

E-print Network

education. Since 1993, Bain & Company has been conducting surveys (every year or two) of tools used by managers (Rigsby, 2011). 7 Higher education CFOs have to manage multifaceted systems with many interrelated, yet unpredictable, components... Universities face increasing indecision, volatility, deregulation, and a scarcity of financial and human capital (Perkin, 2007). Competing social issues, for example crime, gender and race inequality, public welfare, and healthcare and retirement costs create...

Trexler, Grant 1961-

2012-11-16

274

DIP, the Database of Interacting Proteins: a research tool for studying cellular networks of protein interactions  

Microsoft Academic Search

The Database of Interacting Proteins (DIP: http:\\/\\/ dip.doe-mbi.ucla.edu) is a database that documents experimentally determined protein-protein inter- actions. It provides the scientific community with an integrated set of tools for browsing and extracting information about protein interaction networks. As of September 2001, the DIP catalogs ?11 000 unique inter- actions among 5900 proteins from >80 organisms; the vast majority from

Ioannis Xenarios; Lukasz Salwínski; Xiaoqun Joyce Duan; Patrick Higney; Sul-min Kim; David Eisenberg

2002-01-01

275

Confocal laser scanning microscopy as an analytical tool in chromatographic research  

Microsoft Academic Search

In recent years, confocal laser scanning microscopy has been developed into a non-invasive tool to probe intra-particle profiles\\u000a of protein in chromatographic adsorbents. A necessary prerequisite when using this technique lies in the labeling of proteins\\u000a with fluorescent probes. The quality of the obtained results is thus strongly dependent on the probes used, its sensitivity\\u000a on experimental parameters and the

Jürgen Hubbuch; Maria Regina Kula

2008-01-01

276

A software tool for research in linguistics and lexicography: Application to Somali  

Microsoft Academic Search

General-purpose database management systems, whose structure is built in, are not an appropriate solution to situations where problems of translation or areas of research cannot be bounded in advance, for example, when lexicography and linguistic research are closely related. Consequently, an original system has been developed, and is being applied to linguistic and lexicographical data on the Somali language.

Jacqueline Lecarme; Carole Maury

1987-01-01

277

Community-based participatory research and user-centered design in a diabetes medication information and decision tool  

PubMed Central

Background Together, community-based participatory research (CBPR), usercentered design (UCD) and health information technology (HIT) offer promising approaches to improve health disparities in low-resource settings. Objectives This article describes the application of CBPR and UCD principles to the development of iDecide/Decido, an interactive, tailored, web-based diabetes medication education and decision support tool delivered by community health workers (CHWs) to African-American and Latino participants with diabetes in Southwest and Eastside Detroit. The decision aid is offered in English or Spanish and is delivered on an iPad in participants’ homes. Methods The overlapping principles of CBPR and UCD used to develop iDecide/Decido include: a user-focused or community approach; equitable academic and community partnership in all study phases; an iterative development process that relies on input from all stakeholders; and a program experience that is specified, adapted, and implemented with the target community. Results Collaboration between community members, researchers, and developers is especially evident in the program’s design concept, animations, pictographs, issue cards, goal setting, tailoring, and additional CHW tools. Conclusions Applying the principles of CBPR and UCD can be successfully employed in developing health information tools that are easy to use and understand, interactive, and target health disparities. PMID:23793248

Henderson, Vida A; Barr, Kathryn LC; An, Lawrence C; Guajardo, Claudia; Newhouse, William; Mase, Rebecca; Heisler, Michele

2014-01-01

278

NASA's use of McIDAS technology - A data systems tool for meteorological research and applications  

NASA Technical Reports Server (NTRS)

The Earth Science and Applications Division of the NASA Marshall Space Flight Center has been chartered to conduct research, and to develop and use space technology to gain a basic understanding of the earth processes with emphasis on atmospheric processes. An integral part of the research and development efforts has been the Man computer Interactive Data Access System (McIDAS). The McIDAS computer system has permitted integration of data from satellites, aircraft remote sensors, ground based meteorological data sources, and modeled atmospheric radiances. The result has been an increase in knowlege of mesoscale atmospheric processes and has enabled researchers to recommend improvements and suggestions for planned future remote sensing instruments.

Goodman, H. Michael; Meyer, Paul J.

1987-01-01

279

Research award winner: neurodevelopmental assessment of at-risk learners by school nurses and their tools of choice.  

PubMed

Deficits and delays in neurological maturation and development are closely related to academic difficulties. Early assessment and identification of children with such problems promote remediation and the prevention of secondary problems. The purpose of this study was to determine whether school nurses in a region of one Western state perform screenings for neurological deficits, and if so, which tools were used, how results were or could be used, and the school nurses' opinions of the Quick Neurological Screening Test (QNST). A descriptive study design was used and data were gathered using a questionnaire. It was found that school nurses do not routinely perform neurological screening on children at risk for learning disabilities. Reasons for non-use of neurological screening tools were: time constraints, role ambiguity regarding the appropriateness of neurological screening by nurses, and lack of knowledge of neurodevelopmental screening. Recommendations for addressing these issues and opportunities for further research are proposed. PMID:9987266

Bergner, C P; Young-Cureton, V

1998-10-01

280

Logistics Intra-Theater Support Tool: Combining artificial intelligence and operations research techniques  

SciTech Connect

The Logistics Intra-theater Support Tool (LIST) is a prototype system that analyzes courses of action to see if they are logistically feasible. A course of action (COA) specifies the movement of a specified combat force, its supporting forces, and its supplies to a location by a certain time. LIST answers the following questions. Is the intra-theater infrastructure capable of meeting the COA requirements given the assigned resources If the COA is not logistically feasible, what are the bottlenecks How could the COA be modified to improve its feasibility 8 refs., 10 figs.

Van Groningen, C.N.; Duffy, M.K.; Widing, M.A.; Macal, C.M.

1989-01-01

281

Collection of Practical Tips and Tools for Conducting Clinical Research | accrualnet.cancer.gov  

Cancer.gov

The link to the samples, forms, and worksheets is extremely helpful. I am a cancer program consultant assisting a hospital program in building their cancer-related clinical trials accrual. One barrier has been the hesitancy of IRB and other staff to utilize the cancer registry in a planned screening process to identify patients who may be eligible for some studies. The tools in the link yielded several explanations and samples that will be of great benefit in the education process to move forward.

282

Fallout radionuclide-based techniques for assessing the impact of soil conservation measures on erosion control and soil quality: an overview of the main lessons learnt under an FAO/IAEA Coordinated Research Project.  

PubMed

This paper summarizes key findings and identifies the main lessons learnt from a 5-year (2002-2008) coordinated research project (CRP) on "Assessing the effectiveness of soil conservation measures for sustainable watershed management and crop production using fallout radionuclides" (D1.50.08), organized and funded by the International Atomic Energy Agency through the Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture. The project brought together nineteen participants, from Australia, Austria, Brazil, Canada, Chile, China, Japan, Morocco, Pakistan, Poland, Romania, Russian Federation, Turkey, United Kingdom, United States of America and Vietnam, involved in the use of nuclear techniques and, more particularly, fallout radionuclides (FRN) to assess the relative impacts of different soil conservation measures on soil erosion and land productivity. The overall objective of the CRP was to develop improved land use and management strategies for sustainable watershed management through effective soil erosion control practices, by the use of ¹³?Cs (half-life of 30.2 years), ²¹?Pb(ex) (half-life of 22.3 years) and ?Be (half-life of 53.4 days) for measuring soil erosion over several spatial and temporal scales. The environmental conditions under which the different research teams applied the tools based on the use of fallout radionuclides varied considerably--a variety of climates, soils, topographies and land uses. Nevertheless, the achievements of the CRP, as reflected in this overview paper, demonstrate that fallout radionuclide-based techniques are powerful tools to assess soil erosion/deposition at several spatial and temporal scales in a wide range of environments, and offer potential to monitor soil quality. The success of the CRP has stimulated an interest in many IAEA Member States in the use of these methodologies to identify factors and practices that can enhance sustainable agriculture and minimize land degradation. PMID:22336567

Dercon, G; Mabit, L; Hancock, G; Nguyen, M L; Dornhofer, P; Bacchi, O O S; Benmansour, M; Bernard, C; Froehlich, W; Golosov, V N; Haciyakupoglu, S; Hai, P S; Klik, A; Li, Y; Lobb, D A; Onda, Y; Popa, N; Rafiq, M; Ritchie, J C; Schuller, P; Shakhashiro, A; Wallbrink, P; Walling, D E; Zapata, F; Zhang, X

2012-05-01

283

Microgravity: A New Tool for Basic and Applied Research in Space  

NASA Technical Reports Server (NTRS)

This brochure highlights selected aspects of the NASA Microgravity Science and Applications program. So that we can expand our understanding and control of physical processes, this program supports basic and applied research in electronic materials, metals, glasses and ceramics, biological materials, combustion and fluids and chemicals. NASA facilities that provide weightless environments on the ground, in the air, and in space are available to U.S. and foreign investigators representing the academic and industrial communities. After a brief history of microgravity research, the text explains the advantages and methods of performing microgravity research. Illustrations follow of equipment used and experiments preformed aboard the Shuttle and of prospects for future research. The brochure concludes be describing the program goals and the opportunities for participation.

1985-01-01

284

U of Chicago researchers develop new tool that predicts financial pain for cancer patients  

Cancer.gov

Researchers have found that cancer care has a new side effect. Along with the distress that comes with a cancer diagnosis and the discomforts of treatment, more patients now have to deal with "financial toxicity".

285

Biomedical research, a tool to address the health issues that affect African populations  

PubMed Central

Traditionally, biomedical research endeavors in low to middle resources countries have focused on communicable diseases. However, data collected over the past 20 years by the World Health Organization (WHO) show a significant increase in the number of people suffering from non-communicable diseases (e.g. heart disease, diabetes, cancer and pulmonary diseases). Within the coming years, WHO predicts significant decreases in communicable diseases while non-communicable diseases are expected to double in low and middle income countries in sub-Saharan Africa. The predicted increase in the non-communicable diseases population could be economically burdensome for the basic healthcare infrastructure of countries that lack resources to address this emerging disease burden. Biomedical research could stimulate development of healthcare and biomedical infrastructure. If this development is sustainable, it provides an opportunity to alleviate the burden of both communicable and non-communicable diseases through diagnosis, prevention and treatment. In this paper, we discuss how research using biomedical technology, especially genomics, has produced data that enhances the understanding and treatment of both communicable and non-communicable diseases in sub-Saharan Africa. We further discuss how scientific development can provide opportunities to pursue research areas responsive to the African populations. We limit our discussion to biomedical research in the areas of genomics due to its substantial impact on the scientific community in recent years however, we also recognize that targeted investments in other scientific disciplines could also foster further development in African countries. PMID:24143865

2013-01-01

286

Geothermal Electricity Technologies Evaluation Model DOE Tool for Assessing Impact of Research on Cost of Power  

SciTech Connect

The U.S. Department of Energy (DOE) has developed a spreadsheet model to provide insight as to how its research activities can impact of cost of producing power from geothermal energy. This model is referred to as GETEM, which stands for “Geothermal Electricity Technologies Evaluation Model”. Based on user input, the model develops estimates of costs associated with exploration, well field development, and power plant construction that are used along with estimated operating costs to provide a predicted power generation cost. The model allows the user to evaluate how reductions in cost, or increases in performance or productivity will impact the predicted power generation cost. This feature provides a means of determining how specific technology improvements can impact generation costs, and as such assists DOE in both prioritizing research areas and identifying where research is needed.

Greg Mines

2008-01-01

287

A pilot study: research poster presentations as an educational tool for undergraduate epidemiology students  

PubMed Central

Students in a fourth year epidemiology course were surveyed after participating in a formal Science Research Day in which they presented original research, in poster form, to be judged by scientists from the community. Of 276 participating students, 80 (29%) responded to the study survey. As a result, 19% of respondents were more likely to pursue a career in science, and 27.5% were more likely to pursue a career in epidemiology. Only one respondent reported being less likely to pursue a science career, while seven were less likely to pursue epidemiology. A majority of respondents felt that the poster experience was on par with, or superior to, a comparable research paper, in terms of both educational appeal and enjoyment. Mandatory, formal poster presentations are an innovative format for teaching advanced health sciences, and may more accurately reflect the realities of a science career than do more traditional educational formats. PMID:24101888

Deonandan, Raywat; Gomes, James; Lavigne, Eric; Dinh, Thy; Blanchard, Robert

2013-01-01

288

The narrated, nonnarrated, and the disnarrated: conceptual tools for analyzing narratives in health services research.  

PubMed

While analyzing the narratives of children receiving pediatric oncology treatment and their parents, we encountered three ways to look at their narratives: what was narrated, nonnarrated, and disnarrated. The narrated refers to the actors (characters) and events (scenes) individuals decided to include in the narration of their experiences, the nonnarrated are everything not included in narration, and the disnarrated are elements that are narrated in the story but did not actually take place. We use our reflection to illustrate how an integrative analysis of these different forms of narration can allow us to produce a holistic interpretation of people's experiences of illness. This approach is still in the early stages of development, but we hope this article can promote a debate in the field and lead to the refinement of an important tool for narrative analysis. PMID:25192757

Vindrola-Padros, Cecilia; Johnson, Ginger A

2014-11-01

289

Research and Teaching: Two-Dimensional, Implicit Confidence Tests as a Tool for Recognizing Student Misconceptions  

NSDL National Science Digital Library

The misconceptions that students bring with them, or that arise during instruction, are a critical barrier to learning. Implicit-confidence tests, a simple modification of the multiple-choice test, can be used as a strategy for recognizing student misconceptions. An important issue, however, is whether such tests are gender-neutral. We analyzed the results of exams administered to students (both majors and nonmajors) in Molecular, Cellular and Developmental Biology (MCDB) 1111: Biofundamentals at the University of Colorado at Boulder. At a statistically significant level ( 95%), there was no difference between women and men regardless of whether their answers were confidently correct or incorrect, suggesting that such two-dimensional tests are a gender-neutral tool.

Taylor, Linda B.; Klymkowsky, Michael W.; Garvin-Doxas, R. K.; Spindler, Shana R.

2006-11-01

290

Tools for 3D scientific visualization in computational aerodynamics at NASA Ames Research Center  

NASA Technical Reports Server (NTRS)

Hardware, software, and techniques used by the Fluid Dynamics Division (NASA) for performing visualization of computational aerodynamics, which can be applied to the visualization of flow fields from computer simulations of fluid dynamics about the Space Shuttle, are discussed. Three visualization techniques applied, post-processing, tracking, and steering, are described, as well as the post-processing software packages used, PLOT3D, SURF (Surface Modeller), GAS (Graphical Animation System), and FAST (Flow Analysis software Toolkit). Using post-processing methods a flow simulation was executed on a supercomputer and, after the simulation was complete, the results were processed for viewing. It is shown that the high-resolution, high-performance three-dimensional workstation combined with specially developed display and animation software provides a good tool for analyzing flow field solutions obtained from supercomputers.

Bancroft, Gordon; Plessel, Todd; Merritt, Fergus; Watson, Val

1989-01-01

291

DART: Tools and Support for Ensemble Data Assimilation Research, Operations, and Education  

NASA Astrophysics Data System (ADS)

The Data Assimilation Research Testbed (DART) is a community facility for ensemble data assimilation developed and supported by the National Center for Atmospheric Research. DART provides a comprehensive suite of software, documentation, examples and tutorials that can be used for ensemble data assimilation research, operations, and education. Scientists and software engineers from the Data Assimilation Research Section at NCAR are available to actively support DART users who want to use existing DART products or develop their own new applications. Current DART users range from university professors teaching data assimilation, to individual graduate students working with simple models, through national laboratories doing operational prediction with large state-of-the-art models. DART runs efficiently on many computational platforms ranging from laptops through thousands of cores on the newest supercomputers. This poster focuses on recent developments for coupled data assimilation with DART and NCAR's Community Earth System Model. DART interfaces to the Community Atmosphere Model (CAM), the Parallel Ocean Program (POP) and the Community Land Model (CLM) can now be used to do multiple component data assimilation with the fully-coupled CESM prediction model. The software innovations required to enable this are described. The latest results for ensemble assimilation experiments with each of the component models are presented along with initial comparisons to corresponding assimilations with the coupled model. A newly developed DART interface to the Whole Atmosphere Community Climate Model (WACCM) is now available. An overview of results of the relative value of assimilating tropospheric and middle atmosphere observations in WACCM is presented. DART is also used with many other types of geophysical models. Highlights of the latest results using DART with the Weather Research and Forecasting (WRF) model for springtime weather over the central United States are also presented. The poster includes instructions on how to get started using DART for research or educational applications.

Anderson, J. L.; Raeder, K.; Hoar, T. J.; Collins, N.; Kershaw, H.; Romine, G. S.; Liu, H.; Mizzi, A. P.; Lei, L.; Chatterjee, A.; Karspeck, A. R.; Pedatella, N. M.

2013-12-01

292

National Renewable Energy Laboratory (NREL) researchers enhanced this building energy optimization tool to analyze  

E-print Network

's Building America program to direct research, assess emerging technologies, evaluate innovative proto- type if and when the HVAC system is being replaced. To account for the fact that existing homes can include. The calculations include a new life- cycle cost metric, allowing energy savings or fuel costs, for example

293

NREL researchers discover ways to increase accuracy in building energy simulations tools to improve predictions of  

E-print Network

regimes within the uninsulated cavities. The effects of ambient outdoor temperature, the radia- tive properties of building materials, insulation levels, and the temperature dependence of conduction through framing members were considered. The research showed that the temperature dependence of conduction through

294

Unpacking the Potential of Educational Gaming: A New Tool for Gaming Research  

ERIC Educational Resources Information Center

The article begins by reviewing the theoretical bases for the contention that advanced computer-based educational gaming can provide powerful learning experiences, and overviews the limited research on the use of such games. Although studies to date have generally supported their value, most of the published investigations have methodological…

Wideman, Herbert H.; Owston, Ronald D.; Brown, Christine; Kushniruk, Andre; Ho, Francis; Pitts, Kevin C.

2007-01-01

295

Automated riverine landscape characterization: GIS-based tools for watershed-scale research, assessment, and management  

EPA Science Inventory

River systems consist of hydrogeomorphic patches (HPs) that emerge at multiple spatiotemporal scales. Functional process zones (FPZs) are HPs that exist at the river valley scae and are important strata for fraing whole-watershed research questions and management plans. Hierarchi...

296

THE UK ENERGY RESEARCH ATLAS: A TOOL FOR PRIORITISING AND PLANNING Prof Jim Skea  

E-print Network

and climate change are stimulating a resurgence of interest in energy­related research and development after been put. INTRODUCTION AND RATIONALE In many countries, the twin concerns of energy security priority, individual countries, bodies such as the European Union and administrations at the sub-national

297

Driving 21st Century Research and Education with 21st Century Tools  

E-print Network

­ It is now possible to build a picture of the Milky Way galaxy star by star ­ discovered a dozen dwarfst Century Research · Key questions: ­ What does the Milky Way Galaxy look like? ­ How was it formed (and by example how did galaxies form in general)? ­ How is dark matter distributed in the Milky Way

Barr, Valerie

298

“Underground Safari” and other outreach tools for dissemination of root and soil science research  

NASA Astrophysics Data System (ADS)

The Kalahari Transect encompasses the sandy savanna biome of southern Africa and provides a compelling setting for studying the influence of climate change on soil and plant dynamics in a water stressed environment. NSF funding for the Research Experience for Teachers (RET) Program made it possible for a high school science teacher to visit field sites in Botswana, interact with Botswana high school teachers and students, and collaborate with scientists to develop web-based science teacher education modules on the topic of roots and belowground carbon storage. The “Underground Safari” website for K-12 teachers and students was constructed to infuse middle and high school level standards-based soil science curricula with outdoor activities, international field research videos, lab demos, printable handouts, and stimulating real-world applications. This presentation highlights the “Underground Safari” website design, the wiki page used by the RET teacher to communicate with her students on-line and take them on science adventures during the international field research, and other educational outreach activities resulting from this international research experience. Figure 1. Wiki page used by RET teacher to communicate with her students while in the field in Botswana, Africa.

Mladenov, N.; Riffel, H.; D'Odorico, P.

2009-12-01

299

Measurement of heart rate variability: a clinical tool or a research toy?  

Microsoft Academic Search

OBJECTIVESThe objectives of this review are to discuss the diversity of mechanisms that may explain the association between heart rate (HR) variability and mortality, to appraise the clinical applicability of traditional and new measures of HR variability and to propose future directions in this field of research. There is a large body of data demonstrating that abnormal HR variability measured

Heikki V Huikuri; Timo Mäkikallio; K. E. Juhani Airaksinen; Raul Mitrani; Agustin Castellanos; Robert J Myerburg

1999-01-01

300

Handbook of Research on Hybrid Learning Models: Advanced Tools, Technologies, and Applications  

ERIC Educational Resources Information Center

Hybrid learning is now the single-greatest trend in education today due to the numerous educational advantages when both traditional classroom learning and e-learning are implemented collectively. This handbook collects emerging research and pedagogies related to the convergence of teaching and learning methods. This significant "Handbook of…

Wang, Fu Lee, Ed.; Fong, Joseph, Ed.; Kwan, Reggie, Ed.

2010-01-01

301

Issues Related to Student Persistence toward Graduation in Public Schools: A Research Based Tool for Educators  

ERIC Educational Resources Information Center

This abstract focuses on a project report addressing persistence toward graduation. The product will provide a comprehensive resource for school district leaders to use in the identification of at-risk students and research based dropout prevention programs. With the passage of "No Child Left Behind" in 2002 legislation has put a greater…

Fritz, Ronald D.; Fisher, Deanne L.; Scott, Nancy L.

2012-01-01

302

Prospective, randomized evaluation of a personal digital assistant-based research tool in the emergency department  

Microsoft Academic Search

BACKGROUND: Personal digital assistants (PDA) offer putative advantages over paper for collecting research data. However, there are no data prospectively comparing PDA and paper in the emergency department. The aim of this study was to prospectively compare the performance of PDA and paper enrollment instruments with respect to time required and errors generated. METHODS: We randomized consecutive patients enrolled in

Morris L Rivera; Jason Donnelly; Blair A Parry; Anthony Dinizio; Charles L Johnson; Jeffrey A Kline; Christopher Kabrhel

2008-01-01

303

The Reference Desk Survey: A Management Tool in an Academic Research Library.  

ERIC Educational Resources Information Center

Findings of a survey of the level of reference service requested at service points conducted at Virginia Polytechnic Institute and State University indicate that, while 20.5 percent of 14,026 questions recorded fall in the reference category, only 0.7 percent required research by professional librarians. Models of reference desk service and…

Kok, Victoria T.; Pierce, Anton B.

1982-01-01

304

Swimming Simulation: A New Tool for Swimming Research and Practical Applications  

Microsoft Academic Search

This chapter covers topics in swimming simulation from a computational fluid dynamics perspective. This perspective means\\u000a emphasis on the fluid mechanics and CFD methodology applied in swimming research. We concentrated on numerical simulation\\u000a results, considering the scientific simulation point-of-view and especially the practical implications with swimmers.

Daniel A. Marinho; Tiago M. Barbosa; Per L. Kjendlie; João P. Vilas-Boas; Francisco B. Alves; Abel I. Rouboa; António J. Silva

305

Development of proteomic and metabolomic tools for application in aquatic invertebrate ecotoxicological research  

Microsoft Academic Search

As a result of intensive use, atrazine is one of the most commonly detected contaminants in surface waters in the Midwestern United States. Atrazine and two of its primary metabolites, desethylatrazine (DEA) and deisopropylatrazine (DIA), are routinely detected in aqueous systems throughout this area. Although research has been conducted on the toxicity of atrazine, limited information exists regarding the toxicity

Kimberly J Ralston-Hooper

2009-01-01

306

Fitts''law as a research and design tool in human-computer interaction  

Microsoft Academic Search

According to Fitts' law, human movement can be modeled by analogy to the transmission of information. Fitts' popular model has been widely adopted in numerous research areas, including kinematics, human factors, and (recently) human-computer interaction (HCI). The present study provides a historical and theoretical context for the model, including an analysis of problems that have emerged through the systematic deviation

I. Scott Mackenzie

1992-01-01

307

Using Research Based Assessment Tools in Professional Development in Current Electricity  

ERIC Educational Resources Information Center

We present a practical way of adapting and using four research-based assessments for different purposes in an electricity and magnetism course for K-8 science teachers. The course is designed to accomplish conceptual change toward accepted scientific conceptions as well as introducing teachers to materials and activities appropriate for their…

Shen, Ji; Gibbons, Patrick C.; Wiegers, John F.; McMahon, Ann P.

2007-01-01

308

ERTS-A data as a teaching and research tool in the Department of Geology  

NASA Technical Reports Server (NTRS)

The author has identified the following significant results. The project was an attempt to integrate ERTS-1 data into teaching introductory, specialized, and graduate courses in the Department of Geology, University of Alaska. This data was to be utilized principally through a specially selected, high quality collection of black and white, and color 9.5 mosaics of the State of Alaska. In completing these tasks, the data accumulated has proved highly useful in a variety of ways including: (1) discussions of the uses and availability of ERTS imagery; (2) as a medium for talking about and showing various areas of Alaska; (3) in discussing geology in general; and (4) as an aid in doing research and as possible research topics themselves. Use of ERTS-1 imagery in geology proved highly successful and its use is now an integral part of many courses.

Grybeck, D. (principal investigator)

1974-01-01

309

Intermediate energy heavy ions: An emerging multi-disciplinary research tool  

SciTech Connect

In the ten years that beams of intermediate energy ({approx}50 MeV/amu{le}E{le}{approx}2 GeV/amu) heavy ions (Z{le}92) have been available, an increasing number of new research areas have been opened up. Pioneering work at the Bevalac at the Lawrence Berkeley Laboratory, still the world's only source of the heaviest beams in this energy range, has led to the establishment of active programs in nuclear physics, atomic physics, cosmic ray physics, as well as biology and medicine, and industrial applications. The great promise for growth of these research areas has led to serious planning for new facilities capable of delivering such beams; several such facilities are now in construction around the world. 20 refs., 5 figs., 1 tab.

Alonso, J.R.

1988-10-01

310

FROM THE AERIAL PHOTO TO HIGH RESOLUTION SATELLITE IMAGE. TOOLS FOR THE ARCHAEOLOGICAL RESEARCH  

Microsoft Academic Search

ThS20 ABSTRACT: The aim of this project is to evaluate the possibilities that the high resolution satellite image offers in the field of archaeological research. More specific, the present study concerns the identification of buried archaeological remains with the aid of the Pan- sharpened (fused) image Quickbird-2. For this purpose, the fused image (spatial resolution 0.70m and spectral resolution 4

O. Georgoula; D. Kaimaris; M. Tsakiri; P. Patias

311

Wild-derived mouse stocks: an underappreciated tool for aging research  

Microsoft Academic Search

Virtually all biomedical research makes use of a relatively small pool of laboratory-adapted, inbred, isogenic stocks of mice.\\u000a Although the advantages of these models are many, there are a number of disadvantages as well. When studying a multifaceted\\u000a process such as aging, the problems associated with using laboratory stocks are greatly inflated. On the other hand, wild-derived\\u000a mouse stocks, loosely

James M. Harper

2008-01-01

312

NASA Global Hawk Project Update and Future Plans: A New Tool for Earth Science Research  

NASA Technical Reports Server (NTRS)

Science objectives include: First demonstration of the Global Hawk unmanned aircraft system (UAS) for NASA and NOAA Earth science research and applications; Validation of instruments on-board the Aura satellite; Exploration of trace gases, aerosols, and dynamics of remote upper Troposphere/lower Stratosphere regions; Sample polar vortex fragments and atmospheric rivers; Risk reduction for future missions that will study hurricanes and atmospheric rivers.

Naftel, Chris

2009-01-01

313

PET as an advanced tool for new drug research and development: pharmacokinetics study of FK960  

Microsoft Academic Search

Objectives: Recently, we have used animal and clinical PET for new drug research and development. In such clinical investigation, Good Manufacturing Practice (GMP) and Good Clinical Practice (GCP) regulations are required, and a series of the PET studies of FK960 [N-(4-acetyl-1-piperazinyl)-p-fluorobenzamide monohydrate], a novel antidementia drug, was examined for predicting accurate clinical dose. Methods: (1) Synthesis of [18F]FK960: We developed

Shintaro Nishimura; Ichiro Matsunari; Yoshihiro Murakami; Hiroyuki Takamatsu; Akihiro Noda; Kazuyoshi Yajima; Masamichi Matsudaira; Masatoshi Itoh; Norihisa Tonami; Kinichi Hisada

2004-01-01

314

IT Research Services: Powerful Tools to Track a Fast Moving Industry  

NASA Technical Reports Server (NTRS)

Research services change and evolve over time, sometimes suddenly, in their focus, topics, formats, service model, etc. You have to check in often. Some offer products that you can customize to your environment, others not so much. You will find a variation in customer management practices (e.g., when and how they share information) ...can sometimes be annoying. Assess your needs carefully. Each research service has a very different service model. Explore ways to share or lower the cost. Someone out there may share the expense when that is an option. Make sure you read the small print. It can work for you as well as against you. When in doubt, ask your Vendor's POC. Set up Research Service "gurus or SME's." Not to violate the copyright agreement of course, just have someone who knows what's there. After you subscribe, reassess.Get the most out of your investment. Some early enthusiasts will fade, and there will be others who don't know it's there and can use it.

Hunter, Paul

2010-01-01

315

Glycine and GABAA Ultra-Sensitive Ethanol Receptors as Novel Tools for Alcohol and Brain Research.  

PubMed

A critical obstacle to developing effective medications to prevent and/or treat alcohol use disorders is the lack of specific knowledge regarding the plethora of molecular targets and mechanisms underlying alcohol (ethanol) action in the brain. To identify the role of individual receptor subunits in ethanol-induced behaviors, we developed a novel class of ultra-sensitive ethanol receptors (USERs) that allow activation of a single receptor subunit population sensitized to extremely low ethanol concentrations. USERs were created by mutating as few as four residues in the extracellular loop 2 region of glycine receptors (GlyRs) or ?-aminobutyric acid type A receptors (GABAARs), which are implicated in causing many behavioral effects linked to ethanol abuse. USERs, expressed in Xenopus oocytes and tested using two-electrode voltage clamp, demonstrated an increase in ethanol sensitivity of 100-fold over wild-type receptors by significantly decreasing the threshold and increasing the magnitude of ethanol response, without altering general receptor properties including sensitivity to the neurosteroid, allopregnanolone. These profound changes in ethanol sensitivity were observed across multiple subunits of GlyRs and GABAARs. Collectively, our studies set the stage for using USER technology in genetically engineered animals as a unique tool to increase understanding of the neurobiological basis of the behavioral effects of ethanol. PMID:25245406

Naito, Anna; Muchhala, Karan H; Asatryan, Liana; Trudell, James R; Homanics, Gregg E; Perkins, Daya I; Davies, Daryl L; Alkana, Ronald L

2014-12-01

316

Validation of the 4D NCAT simulation tools for use in high-resolution x-ray CT research  

NASA Astrophysics Data System (ADS)

We validate the computer-based simulation tools developed in our laboratory for use in high-resolution CT research. The 4D NURBS-based cardiac-torso (NCAT) phantom was developed to provide a realistic and flexible model of the human anatomy and physiology. Unlike current phantoms in CT, the 4D NCAT has the advantage, due to its design, that its organ shapes can be changed to realistically model anatomical variations and patient motion. To efficiently simulate high-resolution CT images, we developed a unique analytic projection algorithm (including scatter and quantum noise) to accurately calculate projections directly from the surface definition of the phantom given parameters defining the CT scanner and geometry. The projection data are reconstructed into CT images using algorithms developed in our laboratory. The 4D NCAT phantom contains a level of detail that is close to impossible to produce in a physical test object. We, therefore, validate our CT simulation tools and methods through a series of direct comparisons with data obtained experimentally using existing, simple physical phantoms at different doses and using different x-ray energy spectra. In each case, the first-order simulations were found to produce comparable results (<12%). We reason that since the simulations produced equivalent results using simple test objects, they should be able to do the same in more anatomically realistic conditions. We conclude that, with the ability to provide realistic simulated CT image data close to that from actual patients, the simulation tools developed in this work will have applications in a broad range of CT imaging research.

Segars, W. P.; Mahesh, Mahadevappa; Beck, T.; Frey, E. C.; Tsui, B. M. W.

2005-04-01

317

Software Tools  

Cancer.gov

Software Tools What is caBIG®? NCI's Cancer Biomedical Informatics Grid (caBIG®) is a virtual network of interconnected data, individuals, and organizations that redefines how research is conducted, care is provided, and patients/participants interact

318

Millipore Corporation, a leader in life science technologies, tools, and services for bioscience research and biopharmaceutical manufacturing, has been working with UCSB scientists for less than  

E-print Network

kidney and prostate diseases. Millipore is now working with UCSB's Office of Technology & Industry and in exchange support them with royalties derived from sales of such tools and other research support." And

Akhmedov, Azer

319

V/STOL Systems Research Aircraft: A Tool for Cockpit Integration  

NASA Technical Reports Server (NTRS)

The next generation ASTOVL aircraft will have a complicated propulsion System. The configuration choices include Direct Lift, Lift-Fan and Lift+Lift /Cruise but the aircraft must also have supersonic performance and low-observable characteristics. The propulsion system may have features such as flow blockers, vectoring nozzles and flow transfer schemes. The flight control system will necessarily fully integrate the aerodynamic surfaces and the propulsive elements. With a fully integrated, fly-by-wire flight/propulsion control system, the options for cockpit integration are interesting and varied. It is possible to decouple longitudinal and vertical responses allowing the pilot to close the loop on flight path and flight path acceleration directly. In the hover, the pilot can control the translational rate directly without having to stabilize the inner rate and attitude loops. The benefit of this approach, reduced workload and increased precision. has previously been demonstrated through several motion-based simulations. In order to prove the results in flight, the V/STOL System Research Aircraft (VSRA) was developed at the NASA Ames Research Center. The VSRA is the YAV-8B Prototype modified with a research flight control system using a series-parallel servo configuration in all the longitudinal degrees of freedom (including thrust and thrust vector angle) to provide an integrated flight and propulsion control system in a limited envelope. Development of the system has been completed and flight evaluations of the response types have been performed. In this paper we will discuss the development of the VSRA, the evolution of the flight path command and translational rate command response types and the Guest Pilot evaluations of the system. Pilot evaluation results will be used to draw conclusions regarding the suitability of the system to satisfy V/STOL requirements.

Stortz, Michael W.; ODonoghue, Dennis P.; Tiffany, Geary (Technical Monitor)

1995-01-01

320

V/STOL systems research aircraft: A tool for cockpit integration  

NASA Technical Reports Server (NTRS)

The next generation ASTOVL aircraft will have a complicated propulsion system. The configuration choices include Direct Lift, Lift-Fan and Lift + Lift/Cruise but the aircraft must also have supersonic performance and low-observable characteristics. The propulsion system may have features such as flow blockers, vectoring nozzles and flow transfer schemes. The flight control system will necessarily fully integrate the aerodynamic surfaces and the propulsive elements. With a fully integrated, fly-by-wire flight/propulsion control system, the options for cockpit integration are interesting and varied. It is possible to de-couple longitudinal and vertical responses allowing the pilot to close the loop on flightpath and flightpath acceleration directly. In the hover, the pilot can control the translational rate directly without having to stabilize the inner rate and attitude loops. The benefit of this approach, reduced workload and increased precision, has previously been demonstrated through several motion-based simulations. In order to prove the results in flight, the V/STOL System Research Aircraft (VSRA) was developed at the NASA Ames Research Center. The VSRA is the YAV-8B Prototype modified with a research flight control system using a series-parallel servo configuration in all the longitudinal degrees of freedom (including thrust and thrust vector angle) to provide an integrated flight and propulsion control system in a limited envelope. Development of the system has been completed and flight evaluations of the response types have been performed. In this paper we will discuss the development of the VSRA, the evolution of the flightpath command and translational rate command response types and the Guest Pilot evaluations of the system. Pilot evaluation results are used to draw conclusions regarding the suitability of the system to satisfy V/STOL requirements.

Stortz, Michael W.; ODonoghue, Dennis P.

1995-01-01

321

The Use if GIS Tools in Tourism Research on the Example of Wodzislaw Poviat  

NASA Astrophysics Data System (ADS)

The activities in name of tourist development in Wodzislaw poviat are the reason to evaluate the tourist land development. The evaluation was prepared on the basis of selected indexes characterizing the level of tourist infrastructure development. It considered: the number of lodgings per km2, the number of restaurants per km2, the amount of additional attractions per km2 and the density of tourist tracks. This database was analyzed by the use of GIS tools. Using GIS software allowed working with large databases and provided the possibility to create a graphic representation of the results. The level of tourist land development is diversified and depends on it function. The cities with the best developed tourist infrastructure are Wodzislaw Slaski, Radlin, Pszow, Rydultowy and town in Odra Valley: Olza, Bukow and Nieboczowy. Pszow, Gorzyce and Godow commons have the biggest density of tourist tracks. Dzia?ania na rzecz rozwoju turystyki w powiecie wodzis?awskim s? powodem do oceny zagospodarowania turystycznego obszaru. Ocen? wykonano w oparciu o wybrane wska?niki, charakteryzuj?ce stopie? rozwoju infrastruktury turystycznej. Uwzgl?dniono: liczb? miejsc noclegowych/km2, liczb? lokali gastronomicznych/km2, liczb? atrakcji dodatkowych/km2 oraz g?sto?? szlaków turystycznych. Baz? danych o zapleczu noclegowym, gastronomicznym, atrakcjach towarzysz?cych i szlakach turystycznych poddano analizom przy u?yciu narz?dzi GIS. Wykorzystanie oprogramowania GIS umo?liwi?o prac? z du?ymi bazami danych i pozwoli?o na graficzn? prezentacj? wyników. Stopie? zagospodarowania turystycznego obszaru jest zró?nicowany i zale?y od pe?nionej przez niego funkcji. Najlepiej rozwini?t? baz? turystyczn? posiadaj? miasta Wodzis?aw ?l?ski, Radlin, Pszów i Rydu?towy oraz miejscowo?ci w Dolinie Odry: Olza, Buków i Nieboczowy. Najwi?ksza g?sto?? szlaków turystycznych wyst?puje w Pszowie oraz w gminach Gorzyce i Godów.

Pukowiec, Katarzyna

2012-01-01

322

Embedding Collada Models in Geobrowser Visualizations: a Powerful Tool for Geological Research and Teaching  

NASA Astrophysics Data System (ADS)

Virtual globes such as NASA World Wind and Google Earth have already revolutionized real time geophysical hazard monitoring and geologic map visualization with basic features such as Network Links, Ground Overlays, Placemarks hyperlinked to field data, and Timespans. However, addition of solid and shell models using Collada (www.collada.org) greatly enhances the potential of geobrowsing for both research and teaching. The Collada XML schema is supported by a range of modeling applications, both commercial and open-source. Collada models permit geological cross sections to be located along the associated map's line of section, core data to be embedded in the original drill holes, and seismic centroid moment tensors to be positioned at their associated epicenters. Structural geological applications include three-dimensional fold and fault shell models that intersect the terrain along topographic traces, as well as oriented stress and strain ellipsoids and surface bump-outs. Models may range in linear scale from 1 km or less to 10,000 km or more, and so may span large portions of the globe. Two years of assessing learning outcomes from class-projects involving geobrowsing suggest improved student visualization, increased geospatial awareness, and heightened enthusiasm for the curriculum. In some cases, significant research results have emerged from geobrowsing class assignments. Most importantly, virtual globes and modeling applications facilitate student generation of course content which is key to effective teaching and learning.

de Paor, D. G.

2007-12-01

323

Use of the i2b2 research query tool to conduct a matched case-control clinical research study: advantages, disadvantages and methodological considerations  

PubMed Central

Background A major aim of the i2b2 (informatics for integrating biology and the bedside) clinical data informatics framework aims to create an efficient structure within which patients can be identified for clinical and translational research projects. Our objective was to describe the respective roles of the i2b2 research query tool and the electronic medical record (EMR) in conducting a case-controlled clinical study at our institution. Methods We analyzed the process of using i2b2 and the EMR together to generate a complete research database for a case–control study that sought to examine risk factors for kidney stones among gastrostomy tube (G-tube) fed children. Results Our final case cohort consisted of 41/177 (23%) of potential cases initially identified by i2b2, who were matched with 80/486 (17%) of potential controls. Cases were 10 times more likely to be excluded for inaccurate coding regarding stones vs. inaccurate coding regarding G-tubes. A majority (67%) of cases were excluded due to not meeting clinical inclusion criteria, whereas a majority of control exclusions (72%) occurred due to inadequate clinical data necessary for study completion. Full dataset assembly required complementary information from i2b2 and the EMR. Conclusions i2b2 was critical as a query analysis tool for patient identification in our case–control study. Patient identification via procedural coding appeared more accurate compared with diagnosis coding. Completion of our investigation required iterative interplay of i2b2 and the EMR to assemble the study cohort. PMID:24479726

2014-01-01

324

Lung Cancer Cell Lines as Tools for Biomedical Discovery and Research  

PubMed Central

Lung cancer cell lines have made a substantial contribution to lung cancer translational research and biomedical discovery. A systematic approach to initiating and characterizing cell lines from small cell and non–small cell lung carcinomas has led to the current collection of more than 200 lung cancer cell lines, a number that exceeds those for other common epithelial cancers combined. The ready availability and widespread dissemination of the lines to investigators worldwide have resulted in more than 9000 citations, including multiple examples of important biomedical discoveries. The high (but not perfect) genomic similarities between lung cancer cell lines and the lung tumor type from which they were derived provide evidence of the relevance of their use. However, major problems including misidentification or cell line contamination remain. Ongoing studies and new approaches are expected to reveal the full potential of the lung cancer cell line panel. PMID:20679594

Girard, Luc; Lockwood, William W.; Lam, Wan L.; Minna, John D.

2010-01-01

325

RenderToolbox3: MATLAB tools that facilitate physically based stimulus rendering for vision research.  

PubMed

RenderToolbox3 provides MATLAB utilities and prescribes a workflow that should be useful to researchers who want to employ graphics in the study of vision and perhaps in other endeavors as well. In particular, RenderToolbox3 facilitates rendering scene families in which various scene attributes and renderer behaviors are manipulated parametrically, enables spectral specification of object reflectance and illuminant spectra, enables the use of physically based material specifications, helps validate renderer output, and converts renderer output to physical units of radiance. This paper describes the design and functionality of the toolbox and discusses several examples that demonstrate its use. We have designed RenderToolbox3 to be portable across computer hardware and operating systems and to be free and open source (except for MATLAB itself). RenderToolbox3 is available at https://github.com/DavidBrainard/RenderToolbox3. PMID:24511145

Heasly, Benjamin S; Cottaris, Nicolas P; Lichtman, Daniel P; Xiao, Bei; Brainard, David H

2014-01-01

326

Update on chloroplast research: new tools, new topics, and new trends.  

PubMed

Chloroplasts, the green differentiation form of plastids, are the sites of photosynthesis and other important plant functions. Genetic and genomic technologies have greatly boosted the rate of discovery and functional characterization of chloroplast proteins during the past decade. Indeed, data obtained using high-throughput methodologies, in particular proteomics and transcriptomics, are now routinely used to assign functions to chloroplast proteins. Our knowledge of many chloroplast processes, notably photosynthesis and photorespiration, has reached such an advanced state that biotechnological approaches to crop improvement now seem feasible. Meanwhile, efforts to identify the entire complement of chloroplast proteins and their interactions are progressing rapidly, making the organelle a prime target for systems biology research in plants. PMID:20924030

Armbruster, Ute; Pesaresi, Paolo; Pribil, Mathias; Hertle, Alexander; Leister, Dario

2011-01-01

327

Web 2.0 collaboration tool to support student research in hydrology - an opinion  

NASA Astrophysics Data System (ADS)

A growing body of evidence suggests that it is unwise to make the a-priori assumption that university students are ready and eager to embrace modern online technologies employed to enhance the educational experience. We present our opinion on employing Wiki, a popular Web 2.0 technology, in small student groups, based on a case-study of using it customized to work as a personal learning environment (PLE1) (Fiedler and Väljataga, 2011) for supporting thesis research in hydrology. Since inception in 2006, the system presented has proven to facilitate knowledge construction and peer-communication within and across groups of students of different academic years and to stimulate learning. Being an open ended and egalitarian system, it was a minimal burden to maintain, as all students became content authors and shared responsibility. A number of unintended uses of the system were also observed, like using it as a backup medium and mobile storage. We attribute the success and sustainability of the proposed Web 2.0-based approach to the fact that the efforts were not limited to the application of the technology, but comprised the creation of a supporting environment with educational activities organized around it. We propose that Wiki-based PLEs are much more suitable than traditional learning management systems for supporting non-classroom education activities like thesis research in hydrology. 1Here we use the term PLE to refer to the conceptual framework to make the process of knowledge construction a personalized experience - rather than to refer to the technology (in this case Wiki) used to attempt implementing such a system.

Pathirana, A.; Gersonius, B.; Radhakrishnan, M.

2012-08-01

328

The Soil Moisture Active and Passive (SMAP) Mission: Improving Science Application Tools and Research  

NASA Astrophysics Data System (ADS)

NASA depends on the science community to identify and prioritize leading-edge scientific questions and the observations required to answer them. The Soil Moisture Active and Passive (SMAP) Mission has been identified as a priority for NASA's Science Mission Directorate through the most recent decadal survey. Following launch in 2014, SMAP will deliver global maps of soil moisture content and surface freeze/thaw state. Global measurements of these variables are critical for terrestrial hydrologic and carbon cycle applications. The SMAP observatory consists of two multipolarization L-band sensors, a radar and radiometer that share a deployable mesh reflector antenna. The combined observations from the two sensors will allow accurate estimation of soil moisture at spatial scales. The wide-swath (1000 km) measurements will allow global mapping of soil moisture and freeze/thaw state with a 2-3 day revisit frequency and 1-2 day revisit in boreal latitudes. The synergy of active and passive observations enables measurements of soil moisture and freeze/thaw state with unprecedented resolution, sensitivity, area coverage and revisit frequency. SMAP data are valuable for both scientific research and practical applications. SMAP has the potential to drive a diverse range of novel research in drought and flood guidance, agricultural productivity estimation, weather forecasting, climate prediction, human health risk analysis and defense systems. The accuracy, resolution, and global coverage of SMAP soil moisture and freeze/thaw measurements will provide new information for many science and applications disciplines. A SMAP Applications Team will explore ways to measure interaction and integration of SMAP data with the Emergency Management User community of Maryland in order to produce quantitative metrics related to long-term projects, milestone completion, and movement of SMAP products into routine operations for emergency response.

Escobar, V. M.; Brown, M. E.; Moran, S. M.

2011-12-01

329

Genetically engineered bacteria: an emerging tool for environmental remediation and future research perspectives.  

PubMed

This minireview explores the environmental bioremediation mediated by genetically engineered (GE) bacteria and it also highlights the limitations and challenges associated with the release of engineered bacteria in field conditions. Application of GE bacteria based remediation of various heavy metal pollutants is in the forefront due to eco-friendly and lesser health hazards compared to physico-chemical based strategies, which are less eco-friendly and hazardous to human health. A combination of microbiological and ecological knowledge, biochemical mechanisms and field engineering designs would be an essential element for successful in situ bioremediation of heavy metal contaminated sites using engineered bacteria. Critical research questions pertaining to the development and implementation of GE bacteria for enhanced bioremediation have been identified and poised for possible future research. Genetic engineering of indigenous microflora, well adapted to local environmental conditions, may offer more efficient bioremediation of contaminated sites and making the bioremediation more viable and eco-friendly technology. However, many challenges are to be addressed concerning the release of genetically engineered bacteria in field conditions. There are possible risks associated with the use of GE bacteria in field condition, with particular emphasis on ways in which molecular genetics could contribute to the risk mitigation. Both environmental as well as public health concerns need to be addressed by the molecular biologists. Although bioremediation of heavy metals by using the genetically engineered bacteria has been extensively reviewed in the past also, but the bio-safety assessment and factors of genetic pollution have been never the less ignored. PMID:21402131

Singh, Jay Shankar; Abhilash, P C; Singh, H B; Singh, Rana P; Singh, D P

2011-07-01

330

The new Metals and Alloys Indexes -- Search Manual: A phase diagram research tool  

SciTech Connect

A new Metals and Alloys (M&A) Indexes to the Powder Diffraction File (PDF) has been developed. These indexes will be immediately useful to material scientists because the indexes share many features with references such as Hansen, Elliot, Shunk, Pearson, and Villars and Calvert. These indexes, as contained in the Search Manual, may be used independently or in conjunction with the Powder Diffraction File. The book contains four indexes: two contain data for all materials in the M&A PDF, and two contain supporting data. The permuted-sort Alphabetical Formula Index brings together all entries containing a given element in alphabetical formula order. It has n entries for an n-component material and a straight-line format for the element being sorted to simplify reading the index. Thus, chemical knowledge can make identifications easier. Further, within binary and ternary phase diagrams, phases are listed in compositional order to facilitate direct use in phase diagram research. The Pearson Symbol Code Index has entries arranged in order of the Pearson Symbol Code, hence one can find all the materials with a given structure, and if desired, compare their atomic contents and lattice parameters. The latter are in the standard Crystal Data setting to aid in structural comparisons. The Common Names Index cross-references common metallurgical names, such as austenite or cementite, to the appropriate PDF data. The Strukturbericht Symbol Index cross-references Strukturbericht Symbols and the equivalent Pearson Symbols and Structure Prototypes. Examples of the uses of this index in phase diagram research are given.

Mueller, M.H. [Argonne National Lab., IL (United States); Wallace, P.L. [Los Alamos National Lab., NM (United States); Huang, T.C. [IBM Research Division, San Jose, CA (United States); Dann, J.N. [OSRAM Sylvania, Towanda, PA (United States)

1993-12-31

331

Tools for Integrating Data Access from the IRIS DMC into Research Workflows  

NASA Astrophysics Data System (ADS)

Web service interfaces at the IRIS Data Management Center (DMC) provide access to a vast archive of seismological and related geophysical data. These interfaces are designed to easily incorporate data access into data processing workflows. Examples of data that may be accessed include: time series data, related metadata, and earthquake information. The DMC has developed command line scripts, MATLAB® interfaces and a Java library to support a wide variety of data access needs. Users of these interfaces do not need to concern themselves with web service details, networking, or even (in most cases) data conversion. Fetch scripts allow access to the DMC archive and are a comfortable fit for command line users. These scripts are written in Perl and are well suited for automation and integration into existing workflows on most operating systems. For metdata and event information, the Fetch scripts even parse the returned data into simple text summaries. The IRIS Java Web Services Library (IRIS-WS Library) allows Java developers the ability to create programs that access the DMC archives seamlessly. By returning the data and information as native Java objects the Library insulates the developer from data formats, network programming and web service details. The MATLAB interfaces leverage this library to allow users access to the DMC archive directly from within MATLAB (r2009b or newer), returning data into variables for immediate use. Data users and research groups are developing other toolkits that use the DMC's web services. Notably, the ObsPy framework developed at LMU Munich is a Python Toolbox that allows seamless access to data and information via the DMC services. Another example is the MATLAB-based GISMO and Waveform Suite developments that can now access data via web services. In summary, there now exist a host of ways that researchers can bring IRIS DMC data directly into their workflows. MATLAB users can use irisFetch.m, command line users can use the various Fetch scripts, Java users can use the IRIS-WS library, and Python users may request data through ObsPy. To learn more about any of these clients see http://www.iris.edu/ws/wsclients/.

Reyes, C. G.; Suleiman, Y. Y.; Trabant, C.; Karstens, R.; Weertman, B. R.

2012-12-01

332

Human engineered heart tissue as a versatile tool in basic research and preclinical toxicology.  

PubMed

Human embryonic stem cell (hESC) progenies hold great promise as surrogates for human primary cells, particularly if the latter are not available as in the case of cardiomyocytes. However, high content experimental platforms are lacking that allow the function of hESC-derived cardiomyocytes to be studied under relatively physiological and standardized conditions. Here we describe a simple and robust protocol for the generation of fibrin-based human engineered heart tissue (hEHT) in a 24-well format using an unselected population of differentiated human embryonic stem cells containing 30-40% ?-actinin-positive cardiac myocytes. Human EHTs started to show coherent contractions 5-10 days after casting, reached regular (mean 0.5 Hz) and strong (mean 100 µN) contractions for up to 8 weeks. They displayed a dense network of longitudinally oriented, interconnected and cross-striated cardiomyocytes. Spontaneous hEHT contractions were analyzed by automated video-optical recording and showed chronotropic responses to calcium and the ?-adrenergic agonist isoprenaline. The proarrhythmic compounds E-4031, quinidine, procainamide, cisapride, and sertindole exerted robust, concentration-dependent and reversible decreases in relaxation velocity and irregular beating at concentrations that recapitulate findings in hERG channel assays. In conclusion this study establishes hEHT as a simple in vitro model for heart research. PMID:22028871

Schaaf, Sebastian; Shibamiya, Aya; Mewe, Marco; Eder, Alexandra; Stöhr, Andrea; Hirt, Marc N; Rau, Thomas; Zimmermann, Wolfram-Hubertus; Conradi, Lenard; Eschenhagen, Thomas; Hansen, Arne

2011-01-01

333

Stereology as a valuable tool in the toolbox of testicular research.  

PubMed

The morphology of the testis may be altered in various developmental, physiological and pathological conditions and these changes are reflected by the alterations in the reproductive capacity. Studying testicular morphology under these conditions or following therapeutic interventions relies on quantitative data. Design-based stereology provides quantitative morphological data on the most important characteristics of the testis. The total volume of the testis, seminiferous tubules, interstitial tissues and germinal epithelium, length, diameter and cross sectional area of the tubules as well as the number of Sertoli, Leydig, myoid cells, spermatogonia, spermatocytes and spermatids can be estimated. The present paper explains and demonstrates accurate and efficient stereological methods of sampling and analysis of testicular specimens according to the basics made by the pioneer stereologists. Second-order stereology can provide additional information on the spatial arrangement of the content of the tissues, cells or organelles in testis. These methods are valuable enough to be included in the toolbox of testicular research and are essential whenever quantitative data on morphological characteristics of the testis are required including testicular biopsy of human or in experimental studies. PMID:23069191

Noorafshan, Ali

2014-01-01

334

Directional coronary atherectomy: from therapeutic device to research tool in coronary artery disease.  

PubMed

Directional coronary atherectomy (DCA) was introduced as a new percutaneous revascularization modality in 1990, and was initially applied to large vessels without tortuosity or calcification, with overall results including a 95% procedural success, 94% clinical success and 4.6% major complications (urgent bypass surgery in 3.8%, Q wave myocardial infarction in 1.7%, and hospital mortality in 0.3% of patients). In addition to its established efficacy for eccentric lesions, newer applications emerged such as treatment of saphenous vein grafts, thrombus-associated lesions, aorto-ostial lesions, failed or suboptional coronary angioplasty results, bifurcation lesions and use as a part of multi-vessel intervention. Comparative studies with coronary angioplasty such as CAVEAT I and II and CCAT showed better success rates with DCA vs coronary angioplasty, but failed to demonstrate benefit in restenosis rates. OARS and BOAT studies helped define optimal atherectomy techniques, which led to better acute angiographic results and to the "debulking plus stenting" concept. A spin-off of those clinical applications has been the opportunity to study the histology of tissue excised by DCA in vivo in different clinical settings. Such studies, investigating plaque ulceration, thrombosis and inflammation are reviewed, with special emphasis on new insights into unstable angina; the future of atherectomy research is also outlined with a categorization of various possible protocols to be applied utilizing coronary atherectomy specimens from live patients. PMID:10371784

Di Sciascio, G; Patti, G

1999-04-01

335

ERTS-A data as a teaching and research tool in the Department of Geology  

NASA Technical Reports Server (NTRS)

The author has identified the following significant results. ERTS-1 prints have been used extensively in a geology of Alaska class to give a basic framework of the geology of the state. In addition, they have been intermittantly used in such diverse classes as: (1) Economic Geology (e.g. the Sn-bearing granites of the Seward Peninsula are particularly noticeable due to their wide contact metamorphic aureoles.) (2) A canned geology of Alaska lecture which has been given to two different introductory geology courses. (3) Structural Geology (e.g. the Fairweather and Denali faults are striking obvious). It was found most convenient for larger classes to prepare 35mm slides of the ERTS-1 prints that are used in conjunction with slides of the topographic and geologic maps at about the same scale. Thus the emphasis has been in integration of the ERTS-1 material into existing courses. As such, the ERTS-1 data has provided a unique and striking viewpoint that never fails to initiate favorable comment. In addition, prints have been examined by numerous researchers to develop a regional, integrated overview of such varied topics as regional geology to a background for local geologic mapping to studies of ore deposits and to the definition of a formation to be studied in detail at its type locality.

Grybeck, D. (principal investigator)

1973-01-01

336

Toward routine use of 3D histopathology as a research tool.  

PubMed

Three-dimensional (3D) reconstruction and examination of tissue at microscopic resolution have significant potential to enhance the study of both normal and disease processes, particularly those involving structural changes or those in which the spatial relationship of disease features is important. Although other methods exist for studying tissue in 3D, using conventional histopathological features has significant advantages because it allows for conventional histopathological staining and interpretation techniques. Until now, its use has not been routine in research because of the technical difficulty in constructing 3D tissue models. We describe a novel system for 3D histological reconstruction, integrating whole-slide imaging (virtual slides), image serving, registration, and visualization into one user-friendly package. It produces high-resolution 3D reconstructions with minimal user interaction and can be used in a histopathological laboratory without input from computing specialists. It uses a novel method for slice-to-slice image registration using automatic registration algorithms custom designed for both virtual slides and histopathological images. This system has been applied to >300 separate 3D volumes from eight different tissue types, using a total of 5500 virtual slides comprising 1.45 TB of primary image data. Qualitative and quantitative metrics for the accuracy of 3D reconstruction are provided, with measured registration accuracy approaching 120 ?m for a 1-cm piece of tissue. Both 3D tissue volumes and generated 3D models are presented for four demonstrator cases. PMID:22490922

Roberts, Nicholas; Magee, Derek; Song, Yi; Brabazon, Keeran; Shires, Mike; Crellin, Doreen; Orsi, Nicolas M; Quirke, Richard; Quirke, Philip; Treanor, Darren

2012-05-01

337

The IVH Score: A novel tool for estimating intraventricular hemorrhage volume: Clinical and research implications*  

PubMed Central

Objective Intraventricular extension of intracerebral hemorrhage (IVH) is an independent predictor of poor outcome. IVH volume may be important in outcome prediction and management; however, it is difficult to measure routinely. Design and Patients We reviewed the charts and computed tomographies of a cohort of consecutive patients with IVH. The cohort was divided into two groups: index and validation by random sampling. IVH and intracerebral hemorrhage (ICH) volume were measured manually in all patients. IVH was also graded using a simple classification system termed IVH score (IVHS). Clinical outcome was determined by the modified Rankin Scale (mRS) at discharge and in-hospital death. Poor outcome was defined as mRS 4–6. Main Results One hundred seventy-five patients were analyzed, 92 in the index group and 83 in the validation group. Exponential regression yielded the following formula for estimating IVH volume (mL): eÎVHS/5 (R2 = .75, p < 0.001). The IVH estimation formula was then verified in the validation group (R2 = .8, p < 0.001). The following correlations with mRS were obtained: IVH volume R = .305; ICH volume R = .468; total volume [TV] R = .571 (p < 0.001 for all three correlations). Partial correlation of TV with mRS controlling for ICH volume yielded R = .3 for TV (p < 0.001). Logistic regression model comparing ICH and TV association with poor outcome yielded the following: ICH odds ratio = 5.2, 95% confidence interval 2.3–11.6, p < 0.001; TV odds ratio = 41.6, 95% confidence interval 9.6–180.6, p < 0.001. Substituting TV for ICH volume in the ICH score resulted in a significant increase in the specificity from 64% to 87% for predicting mortality. Conclusions IVHS enables clinicians to rapidly estimate IVH volume. The addition of IVH to ICH volume increases its predictive power for poor outcome and mortality significantly. IVHS and TV may be used in clinical practice and clinical trials of patients with ICH. PMID:19237905

Hallevi, Hen; Dar, Nabeel S.; Barreto, Andrew D.; Morales, Miriam M.; Martin-Schild, Sheryl; Abraham, Anitha T.; Walker, Kyle C.; Gonzales, Nicole R.; Illoh, Kachikwu; Grotta, James C.; Savitz, Sean I.

2009-01-01

338

MORPHIN: a web tool for human disease research by projecting model organism biology onto a human integrated gene network  

PubMed Central

Despite recent advances in human genetics, model organisms are indispensable for human disease research. Most human disease pathways are evolutionally conserved among other species, where they may phenocopy the human condition or be associated with seemingly unrelated phenotypes. Much of the known gene-to-phenotype association information is distributed across diverse databases, growing rapidly due to new experimental techniques. Accessible bioinformatics tools will therefore facilitate translation of discoveries from model organisms into human disease biology. Here, we present a web-based discovery tool for human disease studies, MORPHIN (model organisms projected on a human integrated gene network), which prioritizes the most relevant human diseases for a given set of model organism genes, potentially highlighting new model systems for human diseases and providing context to model organism studies. Conceptually, MORPHIN investigates human diseases by an orthology-based projection of a set of model organism genes onto a genome-scale human gene network. MORPHIN then prioritizes human diseases by relevance to the projected model organism genes using two distinct methods: a conventional overlap-based gene set enrichment analysis and a network-based measure of closeness between the query and disease gene sets capable of detecting associations undetectable by the conventional overlap-based methods. MORPHIN is freely accessible at http://www.inetbio.org/morphin. PMID:24861622

Hwang, Sohyun; Kim, Eiru; Yang, Sunmo; Marcotte, Edward M.; Lee, Insuk

2014-01-01

339

A multimedia comprehensive informatics system with decision support tools for a multi-site collaboration research of stroke rehabilitation  

NASA Astrophysics Data System (ADS)

Stroke is a major cause of adult disability. The Interdisciplinary Comprehensive Arm Rehabilitation Evaluation (I-CARE) clinical trial aims to evaluate a therapy for arm rehabilitation after stroke. A primary outcome measure is correlative analysis between stroke lesion characteristics and standard measures of rehabilitation progress, from data collected at seven research facilities across the country. Sharing and communication of brain imaging and behavioral data is thus a challenge for collaboration. A solution is proposed as a web-based system with tools supporting imaging and informatics related data. In this system, users may upload anonymized brain images through a secure internet connection and the system will sort the imaging data for storage in a centralized database. Users may utilize an annotation tool to mark up images. In addition to imaging informatics, electronic data forms, for example, clinical data forms, are also integrated. Clinical information is processed and stored in the database to enable future data mining related development. Tele-consultation is facilitated through the development of a thin-client image viewing application. For convenience, the system supports access through desktop PC, laptops, and iPAD. Thus, clinicians may enter data directly into the system via iPAD while working with participants in the study. Overall, this comprehensive imaging informatics system enables users to collect, organize and analyze stroke cases efficiently.

Wang, Ximing; Documet, Jorge; Garrison, Kathleen A.; Winstein, Carolee J.; Liu, Brent

2012-02-01

340

Murine Models of Acute Leukemia: Important Tools in Current Pediatric Leukemia Research  

PubMed Central

Leukemia remains the most common diagnosis in pediatric oncology and, despite dramatic progress in upfront therapy, is also the most common cause of cancer-related death in children. Much of the initial improvement in outcomes for acute lymphoblastic leukemia (ALL) was due to identification of cytotoxic agents that are active against leukemia followed by the recognition that combination of these cytotoxic agents and prolonged therapy are essential for cure. Recent data demonstrating lack of progress in patients for whom standard chemotherapy fails suggests that the ability to improve outcome for these children will not be dramatically impacted through more intensive or newer cytotoxic agents. Thus, much of the recent research focus has been in the area of improving our understanding of the genetics and the biology of leukemia. Although in vitro studies remain critical, given the complexity of a living system and the increasing recognition of the contribution of leukemia extrinsic factors such as the bone marrow microenvironment, in vivo models have provided important insights. The murine systems that are used can be broadly categorized into syngeneic models in which a murine leukemia can be studied in immunologically intact hosts and xenograft models where human leukemias are studied in highly immunocompromised murine hosts. Both of these systems have limitations such that neither can be used exclusively to study all aspects of leukemia biology and therapeutics for humans. This review will describe the various ALL model systems that have been developed as well as discuss the advantages and disadvantages inherent to these systems that make each particularly suitable for specific types of studies. PMID:24847444

Jacoby, Elad; Chien, Christopher D.; Fry, Terry J.

2014-01-01

341

Use of social network analysis tools to validate a resources infrastructure for interinstitutional translational research: a case study*  

PubMed Central

Question: How can knowledge management and innovative technology, cornerstones of library practice, be leveraged to validate the progress of Clinical and Translational Science Awards? Setting: The Indiana Clinical and Translational Sciences Institute (Indiana CTSI) promotes interdisciplinary research across academic institutions. Methods: Using social networking tools and knowledge management skills enabled the department of knowledge informatics and translation to create a visualization of utilization of resources across different Indiana CTSI programs and coauthorship and citation patterns. Results: Contacts with different resources per investigator increased; every targeted program was shown to be linked to another. Analysis of publications established a baseline to further analyze the scientific contribution of Indiana CTSI projects. Conclusion: Knowledge management and social networking utilities validated the efficacy of the Indiana CTSI resources infrastructure and demonstrated visualization of collaboration. The bibliometric analysis of publications provides a basis for assessing longer-term contributions of support to scientific discovery and transdisciplinary science. PMID:22272159

Hunt, Joe D; Whipple, Elizabeth C; McGowan, Julie J

2012-01-01

342

An adapted version of Intervention Mapping (AIM) is a tool for conducting community-based participatory research.  

PubMed

The field of public health is increasingly using community-based participatory research (CBPR) to address complex health problems such as childhood obesity. Despite the growing momentum and funding base for doing CBPR, little is known about how to undertake intervention planning and implementation in a community-academic partnership. An adapted version of Intervention Mapping (AIM) was created as a tool for university and elementary school partners to create school-level environment and policy changes aimed at increasing student physical activity and healthy eating. After AIM was completed, interviews were conducted with school partners. Findings indicate AIM is closely aligned to 7 of 9 CBPR principles. Examples include equitable involvement of all partners, co-learning, and balancing knowledge generation and community improvement. Shortcomings, lessons learned, and suggestions for strengthening the AIM process are described. PMID:19515863

Belansky, Elaine S; Cutforth, Nick; Chavez, Robert A; Waters, Emily; Bartlett-Horch, Kandiss

2011-05-01

343

Event detection using population-based health care databases in randomized clinical trials: a novel research tool in interventional cardiology  

PubMed Central

Aim To describe a new research tool, designed to reflect routine clinical practice and relying on population-based health care databases to detect clinical events in randomized clinical trials. Background Randomized clinical trials often focus on short-term efficacy and safety in a controlled environment. Trial follow-up may be linked with study-related investigations and differ from routine clinical practice. Because treatment and control in randomized trials differ from daily practice, trial results may have reduced general applicability and may be of limited value in clinical decision-making. Further, it is economically very costly to conduct randomized clinical trials. Methods and results Population-based health care databases collect data continuously and prospectively, and make it possible to monitor lifelong outcomes of cardiac interventions in large numbers of patients. This strengthens external validity by eliminating the effects of study-related monitoring or diagnostic tests. Further, follow-up data can be obtained at low expense. Importantly, data sources encompassing a complete population are likely to reflect clinical practice. Because population-based health care databases collect data for quality-control and administrative purposes unrelated to scientific investigations, certain biases, such as nonresponse bias, recall bias, and bias from losses to follow-up, can be avoided. Conclusion Event detection using population-based health care databases is a new research tool in interventional cardiology that may allow large, low-cost, randomized clinical trials to reflect daily clinical practice, covering a broad range of patients and end points with complete lifelong follow-up. PMID:24068874

Thuesen, Leif; Jensen, Lisette Okkels; Tilsted, Hans Henrik; Maeng, Michael; Terkelsen, Christian; Thayssen, Per; Ravkilde, Jan; Christiansen, Evald H?j; B?tker, Hans Erik; Madsen, Morten; Lassen, Jens F

2013-01-01

344

Pain Measurement Tools and Methods in Clinical Research in Palliative Care: Recommendations of an Expert Working Group of the European Association of Palliative Care  

Microsoft Academic Search

An Expert Working Group was convened under the auspices of the Steering Committee of the Research Network of the European Association of Palliative Care to review the status of the use of pain measurement tools (PMTs) in palliative care research conducted in a multilingual- multicenter setting. Based on a literature review and on the experts' opinion, the present work recommends

Augusto Caraceni; Nathan Cherny; Robin Fainsinger

345

NREL researchers are the first to use a high-performance com-puting tool for a large-eddy simulation of an entire wind plant.  

E-print Network

the front row in this plant, and it accurately predicted the overall plant efficiency.The simulation, usingNREL researchers are the first to use a high-performance com- puting tool for a large-eddy simulation of an entire wind plant. Researchers at the National Renewable Energy Laboratory's (NREL) National

346

U.S.-GERMAN BILATERAL WORKING GROUP: International Research Cooperation to Develop and Evaluate Tools and Techniques for Revitalization of Potentially Contaminated Sites  

EPA Science Inventory

The U.S. German Bilateral Working Group originated in 1990 in order to share and transfer information, ideas, tools and techniques regarding environmental research. The U.S. Environmental Protection Agency (EPA)/Office of Research and Development (ORD) and the German Federal Mini...

347

Development of new exploration tools for seabed mineral resources - Result of R/V YOKOSUKA research cruise YK09-09 -  

NASA Astrophysics Data System (ADS)

Detailed information on subsurface structure under seafloor is necessary for the estimation of seabed resources such as the hydrothermal deposit and methane hydrate. Although advantages of geophysical exploration near seafloor are expected for the seabed resource survey, efficient method has not been well-established. The authors started a project to develop exploration tools for seabed resources under the financial support of MEXT-Japan. We carry out research and development mainly regarding measurement of the magnetic field with high-resolution and high-sampling rate electric exploration devices with accurately controlled active source signals. Developed tools will be mounted underwater platforms such as deep-tow system, ROV (remotely operated vehicle), and AUV (autonomous undersea vehicle). We carried out the research cruise (vessel: JAMSTEC R/V YOKOSUKA YK09-09, cruise period: 19-29 July 2009, area surveyed: Kumano-nada, off Kii Peninsula, Japan) to investigate the performance of developed equipments for magnetic exploration. We mounted an Overhauser and two flux-gate magnetometers on the deep-tow and the AUV URASHIMA. To inspect the efficiency of equipments, it is better to measure the magnetic anomaly which is caused by known magnetic source. Therefore, we made a magnetic target which is consisted of 50 neodymium magnets. Before the navigation, the magnetic target was put under water and its position was measured by the acoustic method. The depth of target is about 2,050 meters, and the measurement was performed in the circle of a radius of about 300 meters. The vehicles were navigated at heights of 25 meters for AUV, and about 15 meters for deep-tow. Each of underwater navigation was practiced for two times. Both performances were carried out successfully, which means that we detected the significant magnetic anomalies caused by the target. We will be able to estimate three-dimensional distribution of anomalous magnetic field, and the source property of magnetic target. However, we have to resolve a lot of problems; (1) elimination of noises caused by the vehicles themselves, and their attitude, and (2) precise estimation of the position of vehicles. We will introduce the results of the research cruise and data processing in the presentation. Acknowledgement: We are grateful to captain Mr. E. Ukekura, chief officer Mr. S. Kusaka, chief AUV/DT operator Mr. T. Sakurai, and operation team, who made our difficult trials in the navigation possible by their professional skill. We also thank to the YOKOSUKA marine crew for overall support, and the engineers who take part in the development of equipments. This study is financially supported by the Ministry of Education, Culture, Sports, Science and Technology, Japan.

Harada, M.; Sayanagi, K.; Kasaya, T.; Sawa, T.; Goto, T.; Tada, N.; Ichihara, H.; Asada, M.; Nakajima, T.; Isezaki, N.

2009-12-01

348

Comparison of the effects of using the Crowe Critical Appraisal Tool versus informal appraisal in assessing health research: a randomised trial.  

PubMed

In systematic reviews, evidence-based practice and journal clubs critical appraisal tools are used to rate research papers. However, little evidence exists on whether the critical appraisal tool, subject matter knowledge or research design knowledge affect the appraisal of research papers. A match paired randomised trial was conducted in August/September 2010 in the Faculty of Medicine, Health and Molecular Science, James Cook University, Australia. Ten participants in total were randomly assigned to two groups using either an informal appraisal of research (IA group) or the Crowe Critical Appraisal Tool (CCAT group), a general critical appraisal tool. Participant independently appraised five research papers, where each paper had a different research design. The scores allocated to the papers by each group were analysed. The intraclass correlation coefficient for absolute agreement was 0.76 for the informal appraisal group and 0.88 for the Crowe Critical Appraisal Tool group. The G study showed that in the informal appraisal group 24% of variance in scores was attributable to either the rater or paper × rater interactions, whereas this was 12% in the Crowe Critical Appraisal Tool group. Analysis of covariance showed that there were statistically significant results in the informal appraisal group for subject matter knowledge (F(1,18) = 7.03, P < 0.05 1 tailed, partial ?² = 0.28) and rater (F(4,18) = 4.57, P < 0.05 1 tailed, partial ?² = 0.50). Kendall's tau correlation coefficient also showed a significant weak positive relationship (? = 0.38, P = 0.03) between total score and subject matter knowledge for the informal appraisal group. The Crowe Critical Appraisal Tool was more reliable than an informal appraisal of the research papers. In the informal appraisal group, there were significant effects for rater and subject matter knowledge, whereas the Crowe Critical Appraisal Tool almost eliminated the rater effect, and no subject matter knowledge effect was apparent. There was no research design knowledge effect in either group. The Crowe Critical Appraisal Tool provided much better score reliability and should help readers with different levels and types of knowledge to reach similar conclusions about a research paper. PMID:22093394

Crowe, Michael; Sheppard, Lorraine; Campbell, Alistair

2011-12-01

349

Software Tool for Researching Annotations of Proteins (STRAP): Open-Source Protein Annotation Software with Data Visualization  

PubMed Central

In order that biological meaning may be derived and testable hypotheses may be built from proteomics experiments, assignments of proteins identified by mass spectrometry or other techniques must be supplemented with additional notation, such as information on known protein functions, protein-protein interactions, or biological pathway associations. Collecting, organizing, and interpreting this data often requires the input of experts in the biological field of study, in addition to the time-consuming search for and compilation of information from online protein databases. Furthermore, visualizing this bulk of information can be challenging due to the limited availability of easy-to-use and freely available tools for this process. In response to these constraints, we have undertaken the design of software to automate annotation and visualization of proteomics data in order to accelerate the pace of research. Here we present the Software Tool for Researching Annotations of Proteins (STRAP) – a user-friendly, open-source C# application. STRAP automatically obtains gene ontology (GO) terms associated with proteins in a proteomics results ID list using the freely accessible UniProtKB and EBI GOA databases. Summarized in an easy-to-navigate tabular format, STRAP includes meta-information on the protein in addition to complimentary GO terminology. Additionally, this information can be edited by the user so that in-house expertise on particular proteins may be integrated into the larger dataset. STRAP provides a sortable tabular view for all terms, as well as graphical representations of GO-term association data in pie (biological process, cellular component and molecular function) and bar charts (cross comparison of sample sets) to aid in the interpretation of large datasets and differential analyses experiments. Furthermore, proteins of interest may be exported as a unique FASTA-formatted file to allow for customizable re-searching of mass spectrometry data, and gene names corresponding to the proteins in the lists may be encoded in the Gaggle microformat for further characterization, including pathway analysis. STRAP, a tutorial, and the C# source code are freely available from http://cpctools.sourceforge.net. PMID:19839595

Bhatia, Vivek N.; Perlman, David H.; Costello, Catherine E.; McComb, Mark E.

2009-01-01

350

EXPLORATORY FISHING FOR MAINE HERRING  

E-print Network

of Maine waters were sounded and fished with a lampara seine, gill nets, midwater trawls, and otter trawls for Atlantic herring and to carry on research and developmental work on sardine fishing gear. Original efforts sought along the Maine coast and in the Gulf of Maine. Otter trawl surveys were made during the winters

351

The Marine VHR 2.5-D Seismic Brute Stack Cube as a Feasible Tool for Low Budget Investigation and Research  

NASA Astrophysics Data System (ADS)

Between 1997 and 1999 several marine seismic surveys were carried out in Kiel Bay aimed towards the development of a three-dimensional acquisition and interpretation technique for small scale subsurface structures using high-frequency sources and multichannel streamers. The data set was recently revisited by the author and reprocessed to obtain a multichannel stacked seismic data cube. Nominal hydrophone positions are deduced by determining offsets from first arrival times and estimating the hydrophone positions under consideration of the ships track. Processing towards a ‘seismic cube’ mainly comprised CMP sorting, constant velocity NMO correction and stacking. The resulting VHR 3-D seismic ‘brute stack cube’ reveals rich structural details. The fluvial Pleistocene channel system already documented in an earlier publication was tracked further to the north. It is situated below a flat cover of gas-bearing Holocene sediments, which locally constitute the seafloor. This till-horizon is superimposed on a second till layer showing strong topographic variations. Seismic signal phase and shielding effects indicate the possible presence of gas in these formations. This case history demonstrates that the VHR 3-D seismic method is a feasible tool for low budget investigation and research.

Müller, Christof

2005-06-01

352

Computational challenges and human factors influencing the design and use of clinical research participant eligibility pre-screening tools  

PubMed Central

Background Clinical trials are the primary mechanism for advancing clinical care and evidenced-based practice, yet challenges with the recruitment of participants for such trials are widely recognized as a major barrier to these types of studies. Data warehouses (DW) store large amounts of heterogenous clinical data that can be used to enhance recruitment practices, but multiple challenges exist when using a data warehouse for such activities, due to the manner of collection, management, integration, analysis, and dissemination of the data. A critical step in leveraging the DW for recruitment purposes is being able to match trial eligibility criteria to discrete and semi-structured data types in the data warehouse, though trial eligibility criteria tend to be written without concern for their computability. We present the multi-modal evaluation of a web-based tool that can be used for pre-screening patients for clinical trial eligibility and assess the ability of this tool to be practically used for clinical research pre-screening and recruitment. Methods The study used a validation study, usability testing, and a heuristic evaluation to evaluate and characterize the operational characteristics of the software as well as human factors affecting its use. Results Clinical trials from the Division of Cardiology and the Department of Family Medicine were used for this multi-modal evaluation, which included a validation study, usability study, and a heuristic evaluation. From the results of the validation study, the software demonstrated a positive predictive value (PPV) of 54.12% and 0.7%, respectively, and a negative predictive value (NPV) of 73.3% and 87.5%, respectively, for two types of clinical trials. Heuristic principles concerning error prevention and documentation were characterized as the major usability issues during the heuristic evaluation. Conclusions This software is intended to provide an initial list of eligible patients to a clinical study coordinators, which provides a starting point for further eligibility screening by the coordinator. Because this software has a high “rule in” ability, meaning that it is able to remove patients who are not eligible for the study, the use of an automated tool built to leverage an existing enterprise DW can be beneficial to determining eligibility and facilitating clinical trial recruitment through pre-screening. While the results of this study are promising, further refinement and study of this and related approaches to automated eligibility screening, including comparison to other approaches and stakeholder perceptions, are needed and future studies are planned to address these needs. PMID:22646313

2012-01-01

353

Internet-to-orbit gateway and virtual ground station: A tool for space research and scientific outreach  

NASA Astrophysics Data System (ADS)

Students in higher education, and scientific and technological researchers want to communicate with the International Space Station (ISS), download live satellite images, and receive telemetry, housekeeping and science/engineering data from nano-satellites and larger spacecrafts. To meet this need the Ecuadorian Civilian Space Agency (EXA) has recently provided the civilian world with an internet-to-orbit gateway (Hermes-A/Minotaur) Space Flight Control Center (SFCC) available for public use. The gateway has a maximum range of tracking and detection of 22,000 km and sensitivity such that it can receive and discriminate the signals from a satellite transmitter with power˜0.1 W. The capability is enough to receive the faintest low-earth-orbit (LEO) satellites. This gateway virtually connects participating internet clients around the world to a remote satellite ground station (GS), providing a broad community for multinational cooperation. The goal of the GS is to lower financial and engineering barriers that hinder access to science and engineering data from orbit. The basic design of the virtual GS on a user side is based on free software suites. Using these and other software tools the GS is able to provide access to orbit for a multitude of users without each having to go through the costly setups. We present the design and implementation of the virtual GS in a higher education and scientific outreach settings. We also discuss the basic architecture of the single existing system and the benefits of a proposed distributed system. Details of the software tools and their applicability to synchronous round-the-world tracking, monitoring and processing performed by students and teams at Graz University of Technology, Austria, EXA-Ecuador, University of Michigan, USA and JAXA who have participated in various mission operations and have investigated real-time satellite data download and image acquisition and processing. Students and other remote users at these institutions undergo training with in orbit satellites in preparation for their own use with future university-class nano-satellites' post launch space operations. The exclusive ability of Hermes-A/Minotaur to act as a gateway between remote users (internet) and satellites (in orbit) makes the virtual GS at user-end more feasible for the long-term real-time nano/cubesats space operations. The only requirement is to have a mutual agreement between EXA and participating university/research organization and broadband internet connection at user-end. With successful and remote satellite tracking and downloading of real-time data from many operational satellites, the Hermes has been found a reliable potential GS for current and future university missions and a training platform for individuals pursuing space operations.

Jaffer, Ghulam; Nader, Ronnie; Koudelka, Otto

2011-09-01

354

Pipe dream? Envisioning a grassroots Python ecosystem of open, common software tools and data access in support of river and coastal biogeochemical research (Invited)  

NASA Astrophysics Data System (ADS)

Practical, problem oriented software developed by scientists and graduate students in domains lacking a strong software development tradition is often balkanized into the scripting environments provided by dominant, typically proprietary tools. In environmental fields, these tools include ArcGIS, Matlab, SAS, Excel and others, and are often constrained to specific operating systems. While this situation is the outcome of rational choices, it limits the dissemination of useful tools and their integration into loosely coupled frameworks that can meet wider needs and be developed organically by groups addressing their own needs. Open-source dynamic languages offer the advantages of an accessible programming syntax, a wealth of pre-existing libraries, multi-platform access, linkage to community libraries developed in lower level languages such as C or FORTRAN, and access to web service infrastructure. Python in particular has seen a large and increasing uptake in scientific communities, as evidenced by the continued growth of the annual SciPy conference. Ecosystems with distinctive physical structures and organization, and mechanistic processes that are well characterized, are both factors that have often led to the grass-roots development of useful code meeting the needs of a range of communities. In aquatic applications, examples include river and watershed analysis tools (River Tools, Taudem, etc), and geochemical modules such as CO2SYS, PHREEQ and LOADEST. I will review the state of affairs and explore the potential offered by a Python tool ecosystem in supporting aquatic biogeochemistry and water quality research. This potential is multi-faceted and broadly involves accessibility to lone grad students, access to a wide community of programmers and problem solvers via online resources such as StackExchange, and opportunities to leverage broader cyberinfrastructure efforts and tools, including those from widely different domains. Collaborative development of such tools can provide the additional advantage of enhancing cohesion and communication across specific research areas, and reducing research obstacles in a range of disciplines.

Mayorga, E.

2013-12-01

355

Southern California Earthquake Center--Virtual Display of Objects (SCEC-VDO): An Earthquake Research and Education Tool  

NASA Astrophysics Data System (ADS)

Interns in the program Southern California Earthquake Center/Undergraduate Studies in Earthquake Information Technology (SCEC/UseIT, an NSF Research Experience for Undergraduates Site) have designed, engineered, and distributed SCEC-VDO (Virtual Display of Objects), an interactive software used by earthquake scientists and educators to integrate and visualize global and regional, georeferenced datasets. SCEC-VDO is written in Java/Java3D with an extensible, scalable architecture. An increasing number of SCEC-VDO datasets are obtained on the fly through web services and connections to remote databases; and user sessions may be saved in xml-encoded files. Currently users may display time-varying sequences of earthquake hypocenters and focal mechanisms, several 3-dimensional fault and rupture models, satellite imagery - optionally draped over digital elevation models - and cultural datasets including political boundaries. The ability to juxtapose and interactively explore these data and their temporal and spatial relationships has been particularly important to SCEC scientists who are evaluating fault and deformation models, or who must quickly evaluate the menace of evolving earthquake sequences. Additionally, SCEC-VDO users can annotate the display, plus script and render animated movies with adjustable compression levels. SCEC-VDO movies are excellent communication tools and have been featured in scientific presentations, classrooms, press conferences, and television reports.

Perry, S.; Maechling, P.; Jordan, T.

2006-12-01

356

Soluble MHC-peptide complexes: tools for the monitoring of T cell responses in clinical trials and basic research  

PubMed Central

Soluble MHC-peptide complexes, commonly known as tetramers, allow the detection and isolation of antigen-specific T cells. Although other types of soluble MHC-peptide complexes have been introduced, the most commonly used MHC class I staining reagents are those originally described by Altman and Davis. As these reagents have become an essential tool for T cell analysis, it is important to have a large repertoire of such reagents to cover a broad range of applications in cancer research and clinical trials. Our tetramer collection currently comprises 228 human and 60 mouse tetramers and new reagents are continuously being added. For the MHC II tetramers, the list currently contains 21 human (HLA-DR, DQ and DP) and 5 mouse (I-Ab) tetramers. Quantitative enumeration of antigen-specific T cells by tetramer staining, especially at low frequencies, critically depends on the quality of the tetramers and on the staining procedures. For conclusive longitudinal monitoring, standardized reagents and analysis protocols need to be used. This is especially true for the monitoring of antigen-specific CD4+ T cells, as there are large variations in the quality of MHC II tetramers and staining conditions. This commentary provides an overview of our tetramer collection and indications on how tetramers should be used to obtain optimal results. PMID:19777993

Guillaume, Philippe; Dojcinovic, Danijel

2009-01-01

357

Research Tools to Investigate Movements, Migrations, and Life History of Sturgeons (Acipenseridae), with an Emphasis on Marine-Oriented Populations  

PubMed Central

Worldwide, sturgeons (Acipenseridae) are among the most endangered fishes due to habitat degradation, overfishing, and inherent life history characteristics (long life span, late maturation, and infrequent spawning). As most sturgeons are anadromous, a considerable portion of their life history occurs in estuarine and marine environments where they may encounter unique threats (e.g., interception in non-target fisheries). Of the 16 marine-oriented species, 12 are designated as Critically Endangered by the IUCN, and these include species commercially harvested. We review important research tools and techniques (tagging, electronic tagging, genetics, microchemistry, observatory) and discuss the comparative utility of these techniques to investigate movements, migrations, and life-history characteristics of sturgeons. Examples are provided regarding what the applications have revealed regarding movement and migration and how this information can be used for conservation and management. Through studies that include Gulf (Acipenser oxyrinchus desotoi) and Green Sturgeon (A. medirostris), we illustrate what is known about well-studied species and then explore lesser-studied species. A more complete picture of migration is available for North American sturgeon species, while European and Asian species, which are among the most endangered sturgeons, are less understood. We put forth recommendations that encourage the support of stewardship initiatives to build awareness and provide key information for population assessment and monitoring. PMID:23990959

Nelson, Troy C.; Doukakis, Phaedra; Lindley, Steven T.; Schreier, Andrea D.; Hightower, Joseph E.; Hildebrand, Larry R.; Whitlock, Rebecca E.; Webb, Molly A. H.

2013-01-01

358

Students' Perceptions of the Effectiveness of the World Wide Web as a Research and Teaching Tool in Science Learning  

NASA Astrophysics Data System (ADS)

Students often make little linkage from lesson to lesson on what they learn in the regular classroom. Having them take responsibility for what they are learning is one way of having them think and connect these thoughts together. This qualitative study looks at the use of the World Wide Web (WWW) as a research and teaching tool in promoting self-directed learning in a group of 15 year old students. The perceptions of students on the effectiveness of the World Wide Web in assisting them with the construction of knowledge on Photosynthesis and Respiration are reported and discussed in this paper. The study showed that the students found that the WWW had a number of positive effects on their learning including motivation for independent learning. However, the unedited and unstructured nature of the WWW meant that many of the sites they visited had information that was too difficult to understand and that time was required to improve technical and critical thinking skills to search effectively. The teacher's role as facilitator and guide was crucial to the success of their learning.

Ng, Wan; Gunstone, Richard

2002-08-01

359

Strategic petroleum reserves in Maine  

Microsoft Academic Search

An evaluation was made to determine if the State of Maine should develop a State petroleum storage reserve to protect its economic and social vitality against future petroleum shortages. The requirements for residual oil are delineated and alternate storage options are described. The adequacy of the National Strategic Petroleum Reserve Program (S.P.R.) as a tool for alleviating shortfalls of residual

Tibbetts

1977-01-01

360

L. N. VIN AN -Direc ii de cercetare n domeniul sistemelor multicore / Main Challenges in Multicore Architecture Research, Revista Romana de Informatica si Automatica, ISSN: 1220-  

E-print Network

1 L. N. VIN AN - Direc ii de cercetare în domeniul sistemelor multicore / Main Challenges Bucuresti, vol. 19, nr. 3, 2009, http://www.ici.ro/RRIA/ria2009_3/index.html Direc ii de cercetare în programare paralel, paralelizarea aplica iilor, simularea ca instrument de cercetare, benchmarking

Vintan, Lucian N.

361

Princeton University -Princeton researchers to lead major Pentagon-funded initiatives http://www.princeton.edu/main/news/archive/S24/34/33C25/index.xml?section=topstories[5/27/2009 4:03:22 PM  

E-print Network

://www.princeton.edu/main/news/archive/S24/34/33C25/index.xml?section=topstories[5/27/2009 4:03:22 PM] Other News WebMail A to Z Contacts » Search Topics & PeopleOther News Search News #12;Princeton University - Princeton researchers to lead major Pentagon-funded initiatives http://www.princeton.edu/main/news/archive/S24/34/33C25/index.xml

Aksay, Ilhan A.

362

A research tool for long-term and continuous analysis of fish assemblage in coral-reefs using underwater camera footage  

E-print Network

A research tool for long-term and continuous analysis of fish assemblage in coral-reefs using a better understanding of a complex environment such as a coral reef, collecting data for long-term monitoring of these environments is essential. Long-term monitoring of a coral reef environment can however

Fisher, Bob

363

Single-cell transfection tool enables added control for biological studies May 21, 2013 Northwestern University researchers have developed a new method for delivering molecu  

E-print Network

Single-cell transfection tool enables added control for biological studies May 21, 2013 -- is an increasingly popular method of transfection. (Cell transfection is the introduction of molecules-cell transfection. The new method, called nanofountain probe electroporation (NFP-E), allows researchers to deliver

Espinosa, Horacio D.

364

Case Study: Test Results of a Tool and Method for In-Flight, Adaptive Control System Verification on a NASA F-15 Flight Research Aircraft  

Microsoft Academic Search

This paper presents the Confidence Tool developed at NASA Ames Research Center as a step towards providing a method to provide a metric to monitor adaptive learning algorithm performance in operating conditions for which the correct learning solution is unknown. These control systems primarily comprise learning systems utilizing neural network models, that use large over- parameterized models where the true

Stephen Jacklin; Johann Schumann; John Bosworth; Peggy Williams-Hayes; Richard Larson

365

Integrating Human Health and Environmental Health into the DPSIR Framework: A Tool to Identify Research Opportunities for Sustainable and Healthy Communities  

EPA Science Inventory

The U.S. Environmental Protection Agency has recently realigned its research enterprise around the concept of sustainability. Scientists from across multiple disciplines have a role to play in contributing the information, methods, and tools to more fully understand the long-term...

366

Design and Development of a Knowledge-based Framework for Trouser Procurement: Bid Evaluation Software Tool (BEST); Volume II: Research Methodology.  

National Technical Information Service (NTIS)

Research has been carried out to design and develop BEST (Bid Evaluation Software Tool) a knowledge-based decision support system for evaluating the capability of an apparel manufacturer to perform on a contract. BEST has been developed in cooperation wit...

S. Jayaraman, S. Narayanan, N. Krishna, S. Venkataraman

1996-01-01

367

Where are the gaps in the data lifecycle? Developing policies and workflow tools for digital preservation of research data in the geosciences  

NASA Astrophysics Data System (ADS)

Ongoing work on digital preservation of research data has produced a vast output of models, workflows and software tools, often tailored to specific research environments or software architectures. The presented project (EWIG) is designed to support the transfer of research data from various research environments into digital long-term archives without focusing only on a specific architecture or path in the digital preservation workflow. We aim to identify and to fill existing (policy) gaps throughout the data lifecycle and to develop currently missing workflow components. The emphasis will be on long-term preservation of research data from the geosciences. In cooperation between an infrastructure facility (Zuse-Institute) and two different data producers from the field of geosciences, policies and software tools will be developed to facilitate long-term preservation of research data. Furthermore, during the entire project duration re-use of archived research data is to be tested by scientists, graduates and students in an iterative process. Based on the experience from the test procedures and results we intend to design a university lecture/seminar series, which contributes to raise awareness for data curation issues among students and graduates. The generation of model policies, best-practice documentations and a lecture concept is intended to further the re-use of archived research data by the scientific community.

Peters-Kottig, W.; Klump, J.; Kirchner, I.; Bertelmann, R.; Rusch, B.; Wattenbach, M.; Ulbricht, D.

2011-12-01

368

Programme Specification for the MRes in Biochemical Research PLEASE NOTE. This specification provides a concise summary of the main features of the  

E-print Network

.g. Biochemistry with Management): Biochemical Research 6. Name of Department / Division: Life Sciences ­ Cell: Biosciences Biochemistry is the study of chemical processes which support life. It requires knowledge of key or in industry; · equip students to pursue careers in applied facets of biochemistry in industry, the public

369

Sunnybrook Research Institute (SRI) is a fully affiliated research and teaching hospital with the University of Toronto. The vision of SRI is to invent the future of healthcare and the main aims are to understand and prevent  

E-print Network

personnel (including research associates, engineers, physicists, laboratory technicians and research in each of immunology, medical biophysics and medical imaging. Structure There are three scientific research. Success stories include Colibri, Focused Ultrasound Instruments, Profound Medical, Sentinelle

Barthelat, Francois

370

Mobile Building Energy Audit and Modeling Tools: Cooperative Research and Development Final Report, CRADA Number CRD-11-00441  

SciTech Connect

Broadly accessible, low cost, accurate, and easy-to-use energy auditing tools remain out of reach for managers of the aging U.S. building population (over 80% of U.S. commercial buildings are more than 10 years old*). concept3D and NREL's commercial buildings group will work to translate and extend NREL's existing spreadsheet-based energy auditing tool for a browser-friendly and mobile-computing platform. NREL will also work with concept3D to further develop a prototype geometry capture and materials inference tool operable on a smart phone/pad platform. These tools will be developed to interoperate with NREL's Building Component Library and OpenStudio energy modeling platforms, and will be marketed by concept3D to commercial developers, academic institutions and governmental agencies. concept3D is NREL's lead developer and subcontractor of the Building Component Library.

Brackney, L.

2013-04-01

371

Developing and Using Degenerate Four-Wave Mixing Techniques as a Diagnostic Tool in Discharge and Combustion Research  

NASA Astrophysics Data System (ADS)

Degenerate four-wave mixing (DFWM) is a non-linear spectroscopy producing a coherent signal beam. It has advantages over other laser-based techniques such as Doppler -free and fewer collisional quenching effects than laser -induced fluorescence. In this work, DFWM techniques have been developed to measure OH radicals in a DC discharge with a free jet expansion and OH and CN radicals in atmospheric -pressure flames. These are the first measurements of this kind ever reported. The traditional phase conjugate DFWM (pc-DFWM) setup suffers from strong background noise. In order to reduce the background noise, tilted background pump beam degenerate four-wave mixing (t-DFWM) was developed. Developments are to derive the signal direction, investigate the effects of tilting angle on signal and background noise intensity, and analyze the background noise sources in DFWN measurements. It is found that the beam reflection and Rayleigh scattering are the major sources of background noise. Compared to pc-DFWM, t-DFWM increases the signal-to-noise ratio by 14 times under our experimental conditions. OH radicals produced from a DC discharge with a free jet expansion have been measured by t-DFWM. The rotational temperature is ~60 K within 1.5 mm of the noszle. Beyond 1.5 mm it slowly increases to ~105 K. The differences between the experimental results and calculated concentration and temperature profiles suggest that the discharge process takes place before and during the expansion. The last subject of this research was an investigation of CN reactions in fuel-rich propane/air/nitric oxide flames. The experimental results show that the concentration of CN radicals is increased when the flames are more fuel-rich and maximized at phi=1.65. CN production is due to the reactions of NO with C, CH, CH_2, and C_2H. However, CN is mainly consumed by reacting with OH radicals.

Tsay, Shangjih

372

Talk it up! Integrating traditional telephone research methodologies with e-Social Science tools, methods and practices  

Microsoft Academic Search

Opportunities for expanding the use of the telephone in social science research are now available through the integration of telephone research methods with new and emerging digital technology. This paper discusses some aspects of the use of the telephone in social science research and reports on the use of the telephone in research on the use of mobile communications technology

Collette Snowden

373

RSP Tooling Technology  

SciTech Connect

RSP Tooling{trademark} is a spray forming technology tailored for producing molds and dies. The approach combines rapid solidification processing and net-shape materials processing in a single step. The general concept involves converting a mold design described by a CAD file to a tooling master using a suitable rapid prototyping (RP) technology such as stereolithography. A pattern transfer is made to a castable ceramic, typically alumina or fused silica (Figure 1). This is followed by spray forming a thick deposit of a tooling alloy on the pattern to capture the desired shape, surface texture, and detail. The resultant metal block is cooled to room temperature and separated from the pattern. The deposit's exterior walls are machined square, allowing it to be used as an insert in a standard mold base. The overall turnaround time for tooling is about 3 to 5 days, starting with a master. Molds and dies produced in this way have been used in high volume production runs in plastic injection molding and die casting. A Cooperative Research and Development Agreement (CRADA) between the Idaho National Engineering and Environmental Laboratory (INEEL) and Grupo Vitro has been established to evaluate the feasibility of using RSP Tooling technology for producing molds and dies of interest to Vitro. This report summarizes results from Phase I of this agreement, and describes work scope and budget for Phase I1 activities. The main objective in Phase I was to demonstrate the feasibility of applying the Rapid Solidification Process (RSP) Tooling method to produce molds for the manufacture of glass and other components of interest to Vitro. This objective was successfully achieved.

None

2001-11-20

374

Authorship versus "Credit" for Participation in Research: A Case Study of Potential Ethical Dilemmas Created by Technical Tools Used by Researchers and Claims for Authorship by Their Creators  

PubMed Central

The distinction between authorship and other forms of credit for contribution to a publication has been a persisting controversy that has resulted in numerous guidelines outlining the expected contributions of those claiming authorship. While there have been flagrant, well-publicized deviations from widely accepted standards, they are largely outnumbered by cases that are not publicity-worthy, and therefore remain known to only those directly involved with the inappropriate conduct. We discuss the definition and ethical requirements of authorship, offer a case example of the authorship debate created by a technical tool at our institution, and review parallels that support and dispute the authorship claims of our software developers. Ultimately, we conclude that development of a technical tool that enables data collection does not adequately substitute for contributions to study design and manuscript preparation for authorship purposes. Unless the designers of such a technical tool prospectively participate as a part of the project, they would not have an adequate understanding of the publication’s genesis to defend it publicly and cannot be listed as authors. Therefore, it is incumbent upon project members to invite tool developers to participate at the beginning of such projects, and for tool developers to contribute to study design and manuscript preparation when they desire authorship listings. PMID:17068347

Welker, James A.; McCue, Jack D.

2007-01-01

375

Space Tools! Space Tools!  

E-print Network

of the Universe. Radio telescopes are also used to search for signs of intelligent life on other planets. 13 #12 and planets they saw. The only tools they had to study space were their eyes and their imaginations. They had no other tools to help them learn what these lights in the sky really were. As people studied the night sky

376

"Do We Hear What Children Want to Say?'" Ethical Praxis When Choosing Research Tools with Children under Five  

ERIC Educational Resources Information Center

Over the recent years there has been a shift in the field of early childhood research to involving young children in the research process. A vast body of literature [Evans, P., & Fuller, M. (1996). Hello. Who am I speaking to? Communicating with pre-school children in educational research settings. "Early Years," 17(1), 17-20; Clark,…

Palaiologou, Ioanna

2014-01-01

377

A plant resource and experiment management system based on the Golm Plant Database as a basic tool for omics research  

Microsoft Academic Search

BACKGROUND: For omics experiments, detailed characterisation of experimental material with respect to its genetic features, its cultivation history and its treatment history is a requirement for analyses by bioinformatics tools and for publication needs. Furthermore, meta-analysis of several experiments in systems biology based approaches make it necessary to store this information in a standardised manner, preferentially in relational databases. In

Karin I Köhl; Georg Basler; Alexander Lüdemann; Joachim Selbig; Dirk Walther

2008-01-01

378

Proceedings of Student-Faculty Research Day, CSIS, Pace University, May 6th Forensics Tools for Social Network Security  

E-print Network

designed to protect the users of a Social Networking Site from security threats with a particular focus requests were sent massively. As a result, two networks of friends were created and access was granted Tools for Social Network Security Vishal Almeida, Andrew Karnbad, Palak Shah, and Steve Kim Seidenberg

Tappert, Charles

379

The Colored, Eco-Genetic Relationship Map (CEGRM): A Conceptual Approach and Tool for Genetic Counseling Research  

Microsoft Academic Search

The Colored Ecological and Genetic Relational Map (CEGRM) [pronounced see-gram] is a conceptual approach and tool for presenting information about family and nonkin relationships and stories about inherited diseases in a simple, understandable form. It combines information that can be derived from pedigrees, genograms, ecomaps, and social network analysis in a single, or series of, pictorial maps based on colors

Regina Kenen; June Peters

2001-01-01

380

SBDART: A Research and Teaching Software Tool for Plane-Parallel Radiative Transfer in the Earth's Atmosphere  

Microsoft Academic Search

SBDART is a software tool that computes plane-parallel radiative transfer in clear and cloudy conditions within the earth's atmosphere and at the surface. All important processes that affect the ultraviolet, visible, and infrared radiation fields are included. The code is a marriage of a sophisticated discrete ordinate radiative transfer module, low-resolution atmospheric transmission models, and Mie scattering results for light

Paul Ricchiazzi; Shiren Yang; Catherine Gautier; David Sowle

1998-01-01

381

The In-Depth Interview as a Research Tool for Investigating the Online Intercultural Communication of Asian Internet Users in Relation to Ethics in Intercultural Research  

ERIC Educational Resources Information Center

Virtual intercultural communication is of great interest in intercultural research. How can a researcher gain access to this field of investigation if s/he does not or only partially speaks the languages used by the subjects? This study is an example of how categories relevant to research can be accessed through in-depth interviews. The interview…

Fetscher, Doris

2013-01-01

382

The Principal Component Analysis of X-Ray Fluorescence Spectrometry Data as a Tool for Paleoseismic Research  

NASA Astrophysics Data System (ADS)

To document the magnitude of displacement in past faulting events, observed in excavated paleoseismological trenches across faults, stratigraphic and structural relationships imprinted on the walls should be interpreted. Often, the interpretation is not straightforward. Stratigraphic units on the upthrown block may be subjected to subaerial erosion, while the downthrown block is sometimes poorly stratified with few stratigraphic horizons. Since it is difficult to correlate the lithologic units on the opposite sides of the fault, the reconstruction of past displacements is an equally arduous task. In this work, samples from a recently excavated paleoseismological trench were collected and analyzed with the method of X-ray Fluorescence (XRF) Spectrometry, in order to assess their elemental composition. The XRF data were submitted to Principal Component Analysis (PCA), which is a well-established dimension-reducing statistical technique, applied for pattern recognition in multivariate datasets. The statistical handling aimed to distinguish the base of scarp-derived colluvium(s) from the top of the prefaulting deposits of the downthrown block and infer from which part of the upthrown fault block scarp-derived colluvium and colluvial wedges, parts of the downthrown block were derived and thus estimate displacement. The paleoseismological trench was excavated in Gyrtoni, Larissa, Greece. The excavation yielded excellent results in relation to the recent activity of the Gyrtoni Fault. The south facing Gyrtoni Fault is ~12-13 km long and defines the north boundary of the Middle-Late Quaternary Tyrnavos Basin, at a distance of ca. 10 km from the city of Larissa. The walls of the trench were cleaned and mapped in detail. The footwall of the fault consists of well stratified lagustrine deposits, while the hanging wall consists of poorly stratified scarp-derived deposits. The initial preliminary interpretation of the trench wall structure provided indications of recent reactivations of the fault. Seven samples, one for each lithologic unit, were collected from the upthrown fault block and 10 samples were collected from the downthrown fault block. The samples were dried, pulverized and pressed into standard pellets before carrying out XRF spectrometry measurements. Radioisotope sources (109Cd and 241Am) were used for sample excitation, while X-ray spectra were acquired using a Si(Li) detector coupled with adequate electronics. The concentrations of 17 minor and trace elements (K, Ca, Ti, Cr, Mn, Fe, Cu, Ni, Zn, Rb, Sr, Y, Zr, Ba, La, Ce, Nd) were thus determined. To identify samples of similar composition, the elemental data were treated by PCA using the STATISTICA 8 Statistical Software. The PC score-plots revealed a widely scattered compositional pattern. However, three distinct chemical groups were identified, associated with differences in elemental concentrations. The PCA grouping, combined with geological criteria, allowed distinguishing the colluvial deposits on the downthrown fault block and inferring the provenance of the scarp-derived colluvium and colluvial wedges. An ongoing mineralogical analysis by X-ray diffraction is expected to provide further arguments in this direction. The results indicate that the XRF analysis combined with Principal Component Analysis can serve as a useful tool for paleoseismological research.

Tsodoulos, Ioannis; Papachristodoulou, Christina; Stamoulis, Konstantinos; Ioannides, Konstantinos; Pavlides, Spypos; Caputo, Riccardo; Chatzipetros, Alexandros; Koukouvelas, Ioannis; Kremastas, Evangelos

2013-04-01

383

Integrating human health and environmental health into the DPSIR framework: a tool to identify research opportunities for sustainable and healthy communities.  

PubMed

The U.S. Environmental Protection Agency has recently realigned its research enterprise around the concept of sustainability. Scientists from across multiple disciplines have a role to play in contributing the information, methods, and tools needed to more fully understand the long-term impacts of decisions on the social and economic sustainability of communities. Success will depend on a shift in thinking to integrate, organize, and prioritize research within a systems context. We used the Driving forces-Pressures-State-Impact-Response (DPSIR) framework as a basis for integrating social, cultural, and economic aspects of environmental and human health into a single framework. To make the framework broadly applicable to sustainability research planning, we provide a hierarchical system of DPSIR keywords and guidelines for use as a communication tool. The applicability of the integrated framework was first tested on a public health issue (asthma disparities) for purposes of discussion. We then applied the framework at a science planning meeting to identify opportunities for sustainable and healthy communities research. We conclude that an integrated systems framework has many potential roles in science planning, including identifying key issues, visualizing interactions within the system, identifying research gaps, organizing information, developing computational models, and identifying indicators. PMID:23238563

Yee, Susan H; Bradley, Patricia; Fisher, William S; Perreault, Sally D; Quackenboss, James; Johnson, Eric D; Bousquin, Justin; Murphy, Patricia A

2012-12-01

384

New tools and insights to assist with the molecular identification of Simulium guianense s.l., main Onchocerca volvulus vector within the highland areas of the Amazonia onchocerciasis focus.  

PubMed

Following the success of the Onchocerciasis Elimination Programme for the Americas (OEPA), there is now just one Latin American onchocerciasis focus where onchocerciasis transmission is described as 'on-going:' the Amazonia Onchocerciasis focus. In the hyperendemic highland areas of the Amazonia focus, Simulium guianense s.l. Wise are the most important vectors of the disease. Populations of S. guianense s.l. are, however, known to vary in their cytogenetics and in a range of behaviours, including in their biting habits. In the hypoendemic lowland areas of the Amazonia focus, for example, S. guianense s.l. are generally regarded as zoophilic and consequently unimportant to disease transmission. Robust tools, to discriminate among various populations of S. guianense s.l. have, however, not yet been developed. In the work reported here, we have assessed the utility of a ribosomal DNA sequence fragment spanning the nuclear ribosomal ITS-1, ITS-2 and 5.8S sequence regions and a ?850 nucleotide portion of the mitochondrial cytochrome oxidase gene (CO1) for species-level identification and for resolving the within species substructuring. We report here how we have generated 78 CO1 sequences from a rich set of both zoophilic and anthropophilic populations of S. guianense s.l. that were collected from eight sites that are broadly distributed across Brazil. Consistent with previous findings, our analysis supports the genetic isolation of Simulium litobranchium from S. guianense s.l. In contrast with previous findings, however, our results did not provide support for the divergence of the two species prior to the radiation of S. guianense s.l. In our analysis of the S. guianense s.l. ribosomal DNA sequence trace files we generated, we provide clear evidence of multiple within-specimen single nucleotide polymorphisms and indels suggesting that S. guianense s.l. ribosomal DNA is not a good target for conventional DNA barcoding. This is the first report of S. guianense s.l. within individual ribosomal DNA variation and thus the first evidence that the species is not subject to the normal effects of concerted evolution. Collectively, these data illustrate the need for diverse sampling in the development of robust molecular tools for vector identification and suggest that ribosomal DNA might be able to assist with resolving S. guianense s.l. species substructuring that C01 barcoding has hitherto failed to. PMID:24200838

Crainey, James L; Mattos-Glória, Aline; Hamada, Neusa; Luz, Sérgio L B

2014-03-01

385

Using Census Data to Classify Community College Students by Socioeconomic Status and Community Characteristics. CCRC Research Tools. Number 1  

ERIC Educational Resources Information Center

Colleges and state higher education agencies too often lack accurate information about the socioeconomic status (SES) of their students. This paper describes the methodology that Community College Research Center (CCRC) researchers used to estimate the SES of individual students in the Washington State community and technical college system using…

Crosta, Peter M.; Leinbach, Timothy; Jenkins, Davis

2006-01-01

386

Evaluating Multimedia-Learning Tools Based on Authentic Research Data That Teach Biology Concepts and Environmental Stewardship  

Microsoft Academic Search

High school science teachers and students need interactive, multimedia research- based learning objects that (a) support standards-based teaching, (b) enforce complex thinking and problem solving, (c) embrace research skills, (d) include appropriate assessments to measure student performance, and (e) show \\

Jacqueline McLaughlin; Daniel A. Arbeider; Penn State; Lehigh Valley

2008-01-01

387

Guest Expert: Lauren Wood, MD: Maximizing Our Investment in Clinical Research Through Improved Recruitment Tools | accrualnet.cancer.gov  

Cancer.gov

Please welcome this month’s AccrualNet Guest Expert, Lauren Wood, MD. Dr. Wood is a senior clinical investigator in NCI’s Center for Cancer Research and oversees the implementation and clinical translation of research studies investigating vaccines and immune-based therapies for both cancer and HIV infection.

388

Green tools  

NASA Astrophysics Data System (ADS)

With an eye toward forging tools that the nonscientist can use to make environmentally prudent policy, the National Science Foundation has provided the seed funding to establish a new National Center for Environmental Decision-Making Research. NSF has awarded $5 million over the next five years to the Joint Institute for Energy and the Environment at the University of Tennessee for creation of the center. The organizing principle of the effort, according to NSF, is to "make scientific environmental research more relevant and useful to decision makers." Interdisciplinary teams of sociologists, economists, geologists, ecologists, computer scientists, psychologists, urban planners, and others will be asked to interpret existing research and to conduct new studies of environmental problems and how they were resolved.

389

Wildlife Habitat of Maine  

Microsoft Academic Search

The Wildlife Habitat of Maine map was created using data from the Maine Office of GIS and the United States National Atlas. The map shows the land cover characteristics of Maine, including human development and major roads. The most suitable wildlife habitat can be attributed to the areas with the most suitable land cover and the least human development. An

Wendy Sicard

2005-01-01

390

Trying on and trying out: participatory action research as a tool for literacy and identity work in middle grades classrooms.  

PubMed

This article explores the role of collaborative, ethnographic, participatory action research (PAR) with eighth grade students as a set of possible literacy practices for involving students with issues connected to their lives, resources, language(s), and communities. Findings are based on a year of fieldwork conducted as part of shared inquiry into one public school community's experiences with gentrification and meeting the complex needs of diverse learners. Findings bring to life the ways in which PAR facilitates the redefining of reading, writing, and research; the reconsideration of languages; the rethinking of literacy practices; and the repositioning of participants within and beyond given research endeavors. PMID:20526667

Van Sluys, Katie

2010-09-01

391

A Meta-analysis Method to Advance Design of Technology-Based Learning Tool: Combining Qualitative and Quantitative Research to Understand Learning in Relation to Different Technology Features  

NASA Astrophysics Data System (ADS)

Educators design and create various technology tools to scaffold students' learning. As more and more technology designs are incorporated into learning, growing attention has been paid to the study of technology-based learning tool. This paper discusses the emerging issues, such as how can learning effectiveness be understood in relation to different technology features? And how can pieces of qualitative and quantitative results be integrated to achieve a broader understanding of technology designs? To address these issues, this paper proposes a meta-analysis method. Detailed explanations about the structure of the methodology and its scientific mechanism are provided for discussions and suggestions. This paper ends with an in-depth discussion on the concerns and questions that educational researchers might raise, such as how this methodology takes care of learning contexts.

Zhang, Lin

2013-07-01

392

Web-Enabled and Improved Software Tools and Data Are Needed to Measure Nutrient Intakes and Physical Activity for Personalized Health Research123  

PubMed Central

Food intake, physical activity (PA), and genetic makeup each affect health and each factor influences the impact of the other 2 factors. Nutrigenomics describes interactions between genes and environment. Knowledge about the interplay between environment and genetics would be improved if experimental designs included measures of nutrient intake and PA. Lack of familiarity about how to analyze environmental variables and ease of access to tools and measurement instruments are 2 deterrents to these combined studies. This article describes the state of the art for measuring food intake and PA to encourage researchers to make their tools better known and more available to workers in other fields. Information presented was discussed during a workshop on this topic sponsored by the USDA, NIH, and FDA in the spring of 2009. PMID:20980656

Stumbo, Phyllis J.; Weiss, Rick; Newman, John W.; Pennington, Jean A.; Tucker, Katherine L.; Wiesenfeld, Paddy L.; Illner, Anne-Kathrin; Klurfeld, David M.; Kaput, Jim

2010-01-01

393

ORWARE—a simulation tool for waste management  

Microsoft Academic Search

A simulation model, ORWARE (ORganic WAste REsearch) is described. The model is mainly used as a tool for researchers in environmental systems analysis of waste management. It is a computer-based model for calculation of substance flows, environmental impacts, and costs of waste management. The model covers, despite the name, both organic and inorganic fractions in municipal waste. The model consists

O Eriksson; B Frostell; A Björklund; G Assefa; J.-O Sundqvist; J Granath; M Carlsson; A Baky; L Thyselius

2002-01-01

394

The Queensland high risk foot form (QHRFF) - is it a reliable and valid clinical research tool for foot disease?  

PubMed Central

Background Foot disease complications, such as foot ulcers and infection, contribute to considerable morbidity and mortality. These complications are typically precipitated by “high-risk factors”, such as peripheral neuropathy and peripheral arterial disease. High-risk factors are more prevalent in specific “at risk” populations such as diabetes, kidney disease and cardiovascular disease. To the best of the authors’ knowledge a tool capturing multiple high-risk factors and foot disease complications in multiple at risk populations has yet to be tested. This study aimed to develop and test the validity and reliability of a Queensland High Risk Foot Form (QHRFF) tool. Methods The study was conducted in two phases. Phase one developed a QHRFF using an existing diabetes foot disease tool, literature searches, stakeholder groups and expert panel. Phase two tested the QHRFF for validity and reliability. Four clinicians, representing different levels of expertise, were recruited to test validity and reliability. Three cohorts of patients were recruited; one tested criterion measure reliability (n?=?32), another tested criterion validity and inter-rater reliability (n?=?43), and another tested intra-rater reliability (n?=?19). Validity was determined using sensitivity, specificity and positive predictive values (PPV). Reliability was determined using Kappa, weighted Kappa and intra-class correlation (ICC) statistics. Results A QHRFF tool containing 46 items across seven domains was developed. Criterion measure reliability of at least moderate categories of agreement (Kappa?>?0.4; ICC?>?0.75) was seen in 91% (29 of 32) tested items. Criterion validity of at least moderate categories (PPV?>?0.7) was seen in 83% (60 of 72) tested items. Inter- and intra-rater reliability of at least moderate categories (Kappa?>?0.4; ICC?>?0.75) was seen in 88% (84 of 96) and 87% (20 of 23) tested items respectively. Conclusions The QHRFF had acceptable validity and reliability across the majority of items; particularly items identifying relevant co-morbidities, high-risk factors and foot disease complications. Recommendations have been made to improve or remove identified weaker items for future QHRFF versions. Overall, the QHRFF possesses suitable practicality, validity and reliability to assess and capture relevant foot disease items across multiple at risk populations. PMID:24468080

2014-01-01

395

The Educator in the Law Library: Problems, Bibliography, Research Tools, Analysis of a Case, Glossary of Legal Terms. Third Edition.  

ERIC Educational Resources Information Center

Law books and their use by educators, primarily graduate students of education, are described. Exercises are also presented to introduce the student in education, and in particular in school administration, to some of the main classes of legal materials that will be addressed in a course in school law. The exercises are designed to familiarize the…

Rezny, Arthur A.; Sales, M. Vance

396

The Role of Grid Computing in the Geosciences: Developing a 3D Seismic Waveform Propagation Tool for Seismologists and EarthScope Research  

NASA Astrophysics Data System (ADS)

Advances in the area of information technology (IT) have started to have a significant impact on how geoscientists conduct their daily research activities. Integrated and coordinated resource sharing in the areas of Grid computing, web/grid services, semantic data integration, information management and ontologies along with national computational grids such as TeraGrid now provide tremendous opportunities for geoscientists to conduct novel and efficient research in many areas of the geosciences. One of the national scale projects in this area is the GEON Cyberinfrastructure for the Geosciences Project funded by the NSF. As part of GEON's grid computing environment we have started developing a grid-enabled application (SYNSEIS - SYNthetic SEISmogram generation tool) to help seismologists as well as any other researchers calculate synthetic 3D regional seismic waveforms using a well-tested, finite difference code, E3D, developed by the Lawrence Livermore National Laboratory. SYNSEIS is built as a grid application and accesses distributed data centers and large computational clusters minimizing the requirements needed to conduct such advance calculations. With SYNSEIS users only need to have access to the Internet and a browser. The entire system is web-based and is accessible from the GEONgrid portal web page (www.geongrid.org). It is built using a service-based architecture and each sub-component in the system is also exposed as a web service, allowing multiple use scenarios for each component if other researchers choose to re-use some of the resources. It provides an interactive user interface with mapping tools and event/station/waveform extraction tools that allow users to seamlessly access IRIS Data Management Center's archives. Though the system currently accesses one 3D crustal model across the US, when more models become available they will be incorporated into the system. Users are able to interactively set their study region, retrieve seismic event and station locations, extract waveforms on the fly for any selected event-station pair, and compute a synthetic seismogram using built in tools. As high performence compute engines, SYNSEIS uses national-scale TeraGrid supercomputer centers, hiding all complexities and difficulties related to account management, cpu allocation, and software installation. The system is designed to be used in day-to-day activities of researchers, especially those of EarthScope scientists who will be accessing data from hundreds of stations everyday and need to process the data in a timely fashion.

Seber, D.; Kaiser, T.; Youn, C.; Santini, C.; Greer, D.; Larsen, S.; Glassley, B.

2004-12-01

397

Hand tools: A compilation  

NASA Technical Reports Server (NTRS)

A selection of new hand tools, modifications of existing tools, and techniques developed in the course of NASA research and development projects are presented. The items are presented in two sections: tools for cable and connector applications, and tools for welding applications. Safety is emphasized, together with ease of operation and use in restricted areas or hazardous environments. The discussions are directed primarily toward the technician engaged in assembly or maintenance of mechanical or electrical equipment.

1972-01-01

398

South Columbia Street (Main Hospital)  

E-print Network

W est New Mason Farm Road M anning Drive Drive Deck Cardinal Hospital NC Neuro- Infirmary NC 2nd Wing Patient Support Wing Parking Dogwood Deck UNC HOSPITALS Children's NC Memorial NC Women's cal South Columbia Street wood Dri P Drive Drive West ve (Main Hospital) Old Tarrson Brauer Dental Research

Whitton, Mary C.

399

K6 Mathematics Tools List  

NSDL National Science Digital Library

This web page from Education Development Center in Maine provides an alphabetical list by tool name with links to the 27 learning tools (Java applets). An image, title and description with content tags are provided for each tool. The tools were constructed using the cross-platform open educational resource GeoGebra.

2012-01-01

400

Assessing the proximity of healthy food options and food deserts in a rural area in Maine  

Microsoft Academic Search

The purpose of the project described in this paper was to assess and describe the food environment facing public assistance clients in a rural county in Maine. Using the concept of a “food desert” and an objective tool for rating participating food outlets, the research team developed a spatial model of client access to healthy foods. The final map shows

Teresa A. Hubley

2011-01-01

401

VALIDATION AND EVALUATION OF QUIKSCAT ULTRA-HIGH RESOLUTION WIND RETRIEVAL IN THE GULF OF MAINE  

E-print Network

to the UNH/NASA Research and Discover Program for funding. Fig. 1. Buoy network in the gulf of Maine In many and a geophysical model function. A more recently developed enhanced product now provides wind vectors near-shore processes. Coastal wind users need better tools to understand, model, and predict particu

Long, David G.

402

A dynamic systems engineering methodology research study. Phase 2: Evaluating methodologies, tools, and techniques for applicability to NASA's systems projects  

NASA Technical Reports Server (NTRS)

A study of NASA's Systems Management Policy (SMP) concluded that the primary methodology being used by the Mission Operations and Data Systems Directorate and its subordinate, the Networks Division, is very effective. Still some unmet needs were identified. This study involved evaluating methodologies, tools, and techniques with the potential for resolving the previously identified deficiencies. Six preselected methodologies being used by other organizations with similar development problems were studied. The study revealed a wide range of significant differences in structure. Each system had some strengths but none will satisfy all of the needs of the Networks Division. Areas for improvement of the methodology being used by the Networks Division are listed with recommendations for specific action.

Paul, Arthur S.; Gill, Tepper L.; Maclin, Arlene P.

1989-01-01

403

SBDART: A Research and Teaching Software Tool for Plane-Parallel Radiative Transfer in the Earth's Atmosphere.  

NASA Astrophysics Data System (ADS)

SBDART is a software tool that computes plane-parallel radiative transfer in clear and cloudy conditions within the earth's atmosphere and at the surface. All important processes that affect the ultraviolet, visible, and infrared radiation fields are included. The code is a marriage of a sophisticated discrete ordinate radiative transfer module, low-resolution atmospheric transmission models, and Mie scattering results for light scattering by water droplets and ice crystals. The code is well suited for a wide variety of atmospheric radiative energy balance and remote sensing studies. It is designed so that it can be used for case studies as well as sensitivity analysis. For small sets of computations or teaching applications it is available on the World Wide Web with a user-friendly interface. For sensitivity studies requiring many computations it is available by anonymous FTP as a well organized and documented FORTRAN 77 source code.

Ricchiazzi, Paul; Yang, Shiren; Gautier, Catherine; Sowle, David

1998-10-01

404

Using Social Networking Tools to Promote Genealogy and Local History Collections and to Instruct Researchers in Their Use  

Microsoft Academic Search

Libraries with genealogy and local history collections spend a great deal of time and effort in collecting, preserving, cataloging, indexing, digitizing, and providing access to their materials. However, these activities may be wasted if potential researchers are unaware of the existence of these materials, or are lacking the knowledge and skills to navigate the materials. Many libraries have long used

Andrew M Smith

2010-01-01

405

To Appear: Electronic Networking: Research, Applications, and Policy, 2(1), Spring 1992. Prospero: A Tool for Organizing Internet Resources  

E-print Network

they need. Existing techniques for organizing systems have evolved from those used on centralized systems le systems of di erent types, meaning that di erent mechanisms are needed to access it. Existing Advance Research Projects Agency under NASA Cooperative Agreement NCC-2-539. The views and conclusions

Neuman, Clifford

406

Interpretive Single-Subject Design: A Research Tool for Practitioner-Guided Applied Inquiry in Rural Settings.  

ERIC Educational Resources Information Center

This paper discusses the integration of positivist single-subject design with interpretive, or naturalist, qualitative methods in the development of effective interventions for rural special education students. The resulting research/intervention design includes: (1) extending the normal baseline period from 3 to 10 days thus allowing the…

Hepburn, Eric; And Others

407

A Qualitative Research on the University Administrators' Capacity to Use Management Knowledge Tools (The Case of TRNC Universities)  

ERIC Educational Resources Information Center

In order to reach goals and continue the ongoing learning process, like other organizations, universities also need the effective use of knowledge management. Knowledge management is an ongoing process and it has to be organized in a manner that is always open to new ideas. In universities where research and development studies play an important…

Dagli, Gokmen; Silman, Fatos; Birol, Cem

2009-01-01

408

Issues Related to Student Persistence toward Graduation in Public Schools: A Research-Based Tool for Educators  

ERIC Educational Resources Information Center

This abstract focuses on a project report addressing persistence toward graduation. The product will provide a comprehensive resource for school district leaders to use in the identification of at-risk students and research based dropout prevention programs. With the passage of "No Child Left Behind in 2002" legislation has put a greater…

Scott, Nancy L.; Fisher, Deanne L.; Fritz, Ronald D.

2012-01-01

409

Using the Conceptual Change Model of Learning as An Analytic Tool in Researching Teacher Preparation for Student Diversity  

ERIC Educational Resources Information Center

Background/Context: In regard to preparing prospective teachers for diverse classrooms, the agenda for teacher education research has been primarily concerned with identifying desired outcomes and promising strategies. Scholarship in multicultural education has been crucial for identifying the knowledge, skills, and attitudes needed by teachers to…

Larkin, Douglas

2012-01-01

410

Environmental Inquiry by College Students: Original Research and Peer Review Using Web-Based Collaborative Tools. Preliminary Quantitative Data Analysis.  

ERIC Educational Resources Information Center

The Environmental Inquiry (EI) program (Cornell University and Pennsylvania State University) supports inquiry based, student-centered science teaching on selected topics in the environmental sciences. Texts to support high school student research are published by the National Science Teachers Association (NSTA) in the domains of environmental…

Cakir, Mustafa; Carlsen, William S.

411

Proceedings of Student-Faculty Research Day, CSIS, Pace University, May 4th Social Network Forensic Tools  

E-print Network

and the public will realize a new level of safety on the Internet. However, the proposed use of this technology to the Internet through networks for the purpose of engaging in e-commerce, research and technology are now part sign on to the Internet to join social media portals such as Facebook interact with the best intentions

Tappert, Charles

412

New Tools for Research on Instruction and Instructional Policy: A Web-Based Teacher Log. A CTP Working Paper.  

ERIC Educational Resources Information Center

This paper discusses the initial development and testing of a Web-based instrument for collecting daily data on instruction. This teacher log was developed for use in the Study of Instructional Improvement, a longitudinal study on school improvement in high poverty areas. The researchers wanted to further develop the potential of teacher logs by…

Ball, Deborah Loewenberg; Camburn, Eric; Correnti, Richard; Phelps, Geoffrey; Wallace, Raven

413

Institutional capacity for health systems research in East and Central African schools of public health: experiences with a capacity assessment tool  

PubMed Central

Background Despite significant investments in health systems research (HSR) capacity development, there is a dearth of information regarding how to assess HSR capacity. An alliance of schools of public health (SPHs) in East and Central Africa developed a tool for the self-assessment of HSR capacity with the aim of producing institutional capacity development plans. Methods Between June and November 2011, seven SPHs across the Democratic Republic of Congo, Ethiopia, Kenya, Rwanda, Tanzania, and Uganda implemented this co-created tool. The objectives of the institutional assessments were to assess existing capacities for HSR and to develop capacity development plans to address prioritized gaps. A mixed-method approach was employed consisting of document analysis, self-assessment questionnaires, in-depth interviews, and institutional dialogues aimed at capturing individual perceptions of institutional leadership, collective HSR skills, knowledge translation, and faculty incentives to engage in HSR. Implementation strategies for the capacity assessment varied across the SPHs. This paper reports findings from semi-structured interviews with focal persons from each SPH, to reflect on the process used at each SPH to execute the institutional assessments as well as the perceived strengths and weaknesses of the assessment process. Results The assessment tool was robust enough to be utilized in its entirety across all seven SPHs resulting in a thorough HSR capacity assessment and a capacity development plan for each SPH. Successful implementation of the capacity assessment exercises depended on four factors: (i) support from senior leadership and collaborators, (ii) a common understanding of HSR, (iii) adequate human and financial resources for the exercise, and (iv) availability of data. Methods of extracting information from the results of the assessments, however, were tailored to the unique objectives of each SPH. Conclusions This institutional HSR capacity assessment tool and the process for its utilization may be valuable for any SPH. The self-assessments, as well as interviews with external stakeholders, provided diverse sources of input and galvanized interest around HSR at multiple levels. PMID:24888213

2014-01-01

414

MAINE MARINE WORM HABITAT  

EPA Science Inventory

WORM provides a generalized representation at 1:24,000 scale of commercially harvested marine worm habitat in Maine, based on Maine Department of Marine Resources data from 1970's. Original maps were created by MDMR and published by USF&WS as part of the ""&quo...

415

Exploring Main Belt Asteroids  

Microsoft Academic Search

Terrestrial planet formation in the main asteroid belt was interrupted when growing protoplanets became sufficiently massive to gravitationally perturb the local population, causing bodies to collide with increased energy, thus ending accretion and commencing fragmentation and disruption. Few of these protoplanets are thought to have survived unshattered (e.g., Ceres, Vesta, Pallas), leaving a main belt population dominated by fragments of

M. V. Sykes; S. M. Larson; R. Whiteley; U. Fink; R. Jedicke; J. Emery; R. Fevig; M. Kelley; A. W. Harris; S. Ostro; K. Reed; R. P. Binzel; A. Rivkin; C. Magri; W. Bottke; D. Durda; R. Walker; D. Davis; W. K. Hartmann; D. Sears; H. Yano; J. Granahan; A. Storrs; S. J. Bus; J. F. Bell; D. Tholen; A. Cellino

2001-01-01

416

Southern California Earthquake Center--Virtual Display of Objects (SCEC-VDO): An Earthquake Research and Education Tool  

Microsoft Academic Search

Interns in the program Southern California Earthquake Center\\/Undergraduate Studies in Earthquake Information Technology (SCEC\\/UseIT, an NSF Research Experience for Undergraduates Site) have designed, engineered, and distributed SCEC-VDO (Virtual Display of Objects), an interactive software used by earthquake scientists and educators to integrate and visualize global and regional, georeferenced datasets. SCEC-VDO is written in Java\\/Java3D with an extensible, scalable architecture. An

S. Perry; P. Maechling; T. Jordan

2006-01-01

417

Building a Bridge into the Future: Dynamic Connectionist Modeling as an Integrative Tool for Research on Intertemporal Choice  

PubMed Central

Temporal discounting denotes the fact that individuals prefer smaller rewards delivered sooner over larger rewards delivered later, often to a higher extent than suggested by normative economical theories. In this article, we identify three lines of research studying this phenomenon which aim (i) to describe temporal discounting mathematically, (ii) to explain observed choice behavior psychologically, and (iii) to predict the influence of specific factors on intertemporal decisions. We then opt for an approach integrating postulated mechanisms and empirical findings from these three lines of research. Our approach focuses on the dynamical properties of decision processes and is based on computational modeling. We present a dynamic connectionist model of intertemporal choice focusing on the role of self-control and time framing as two central factors determining choice behavior. Results of our simulations indicate that the two influences interact with each other, and we present experimental data supporting this prediction. We conclude that computational modeling of the decision process dynamics can advance the integration of different strands of research in intertemporal choice. PMID:23181048

Scherbaum, Stefan; Dshemuchadse, Maja; Goschke, Thomas

2012-01-01

418

NEST: NEtwork Server Tool  

Microsoft Academic Search

NEST (network server tool) can be used to automatically generate code infrastructure for TCP-based network servers. It uses a specification language to describe client-server interaction and state transitions within the server. This specification language has some similarities to the compiler tools Lex and Yacc, and its design makes network server specification straightforward. One of the main features of NEST is

Kelly Wilson; John Aycock

2005-01-01

419

Advantages of the CCD camera measurements for profile and wear of cutting tools  

NASA Astrophysics Data System (ADS)

In our paper we prepared an evaluating study of which conclusions draw mainly two directions for our fields of research. On the one hand, this means the measuring of fix, standing workpieces, on the other hand this means geometrical measurement of moving tools. The first case seems to be solved in many respects (in general cases), but the second one is not completely worked out according to the relevant literature. The monitoring of tool wear, the determination of geometrical parameters (this is mainly in case of gear-generating tools) is not really widespread yet, mainly, if optical parameters have influence on the evaluating procedure (e.g. examination of profiles of grinding wheels). We show the elaboration of a process for the practical application of measuring techniques performed by image processing CCD cameras on the basis of wearing criteria of different cutting tools (drilling tool, turning tool). We have made a profile and cutting tool wear measuring program.

Varga, G.; Balajti, Z.; Dudás, I.

2005-01-01

420

The production of intrinsically labeled milk and meat protein is feasible and provides functional tools for human nutrition research.  

PubMed

Administration of labeled, free amino acids does not allow direct assessment of in vivo dietary protein digestion and absorption kinetics. Consequently, dietary protein sources with labeled amino acids incorporated within their protein matrix are required. The aim of the present study was to produce intrinsically L-[1-(13)C]phenylalanine-labeled milk and meat protein that would permit in vivo assessment of postprandial protein digestion and absorption kinetics in humans. One lactating dairy cow was continuously infused with 420 ?mol of L-[1-(13)C]phenylalanine/min for 96 h, with plasma and milk being collected before, during, and after isotope infusion. Twenty-four hours after infusion, the cow was slaughtered to produce intrinsically labeled meat. Levels of L-[1-(13)C]phenylalanine enrichment as high as 40 mole percent excess (MPE) in milk and 1.5 MPE in meat protein were achieved. In a subsequent human proof-of-principle experiment, 2 healthy young males (25±1 yr; 66.2±5.2 kg) each ingested 135 g of L-[1-(13)C]phenylalanine intrinsically labeled minced beef, after which plasma samples were collected at regular time intervals. Plasma L-[1-(13)C]phenylalanine enrichments increased during the first 90 min following beef ingestion, reaching peak plasma enrichment levels of 0.61±0.04 MPE. Whole-body net protein balance, assessed by continuous infusion of L-[ring-(2)H(5)]phenylalanine and L-[ring-(2)H(2)]tyrosine, was higher in the postprandial period compared with basal values (6.4±0.1 vs. -4.5±0.1 ?mol/kg per h). In conclusion, the production of intrinsically L-[1-(13)C]phenylalanine-labeled milk and meat protein is feasible and provides functional tools to investigate in vivo protein digestion and absorption kinetics in humans. PMID:21854909

Pennings, B; Pellikaan, W F; Senden, J M G; van Vuuren, A M; Sikkema, J; van Loon, L J C

2011-09-01

421

Platform Li-Ion Battery Risk Assessment Tool: Cooperative Research and Development Final Report, CRADA Number CRD-10-407  

SciTech Connect

Creare was awarded a Phase 1 STTR contract from the US Office of Naval Research, with a seven month period of performance from 6/28/2010 to 1/28/2011. The objectives of the STTR were to determine the feasibility of developing a software package for estimating reliability of battery packs, and develop a user interface to allow the designer to assess the overall impact on battery packs and host platforms for cell-level faults. NREL served as sub-tier partner to Creare, providing battery modeling and battery thermal safety expertise.

Smith, K.

2012-01-01

422

Integrated piezoelectric actuators in deep drawing tools  

NASA Astrophysics Data System (ADS)

The production of car body panels are defective in succession of process fluctuations. Thus the produced car body panel can be precise or damaged. To reduce the error rate, an intelligent deep drawing tool was developed at the Fraunhofer Institute for Machine Tools and Forming Technology IWU in cooperation with Audi and Volkswagen. Mechatronic components in a closed-loop control is the main differentiating factor between an intelligent and a conventional deep drawing tool. In correlation with sensors for process monitoring, the intelligent tool consists of piezoelectric actuators to actuate the deep drawing process. By enabling the usage of sensors and actuators at the die, the forming tool transform to a smart structure. The interface between sensors and actuators will be realized with a closed-loop control. The content of this research will present the experimental results with the piezoelectric actuator. For the analysis a production-oriented forming tool with all automotive requirements were used. The disposed actuators are monolithic multilayer actuators of the piezo injector system. In order to achieve required force, the actuators are combined in a cluster. The cluster is redundant and economical. In addition to the detailed assembly structures, this research will highlight intensive analysis with the intelligent deep drawing tool.

Neugebauer, R.; Mainda, P.; Drossel, W.-G.; Kerschner, M.; Wolf, K.

2011-04-01

423

The Maine Music Box  

NSDL National Science Digital Library

Created through a collaboration between the University of Maine's Fogler Library and other Maine libraries, The Maine Music Box contains hundreds of digitized sheet music scores from five major collections. First-time visitors to the site will want to click on the "About Maine Music Box" project as a way of getting started. Here they can check out the "User Information" area, which contains helpful tips on viewing the music and how to best browse the entire database. Additionally, those with a penchant for technical details and information science in general can also learn in copious detail how the database was created for this project. From there, visitors can move straight away into the main collection. Visitors can browse the collection by music subject, sheet music cover art, or just type in their own keywords. One of the best ways to look over the collection is to browse around in such areas as "Instructional Violin", "Maine Collection" and "Parlor Salon Collection". It's also worth remarking that this site may inspire a sing-a-long, a campfire get-together, or a miniature Chautauqua.

424

Optical techniques as validation tools for finite element modeling of biomechanical structures, demonstrated in bird ear research  

NASA Astrophysics Data System (ADS)

In this paper we demonstrate the potential of stroboscopic digital holography and laser vibrometry as tools to gather vibration data and validate modelling results in complex biomechanical systems, in this case the avian middle ear. Whereas the middle ear of all mammal species contains three ossicles, birds only feature one ossicle, the columella. Despite this far simpler design, the hearing range of most birds is comparable to mammals, and is adapted to operate under very diverse atmospheric circumstances. This makes the investigation of the avian middle ear potentially very meaningful, since it could provide knowledge that can improve the design of prosthetic ossicle replacements in humans such as a TORP (Total Ossicle Replacement Prosthesis). In order to better understand the mechanics of the bird's hearing, we developed a finite element model that simulates the transmission of an incident acoustic wave on the eardrum via the middle ear structures to the fluid of the inner ear. The model is based on geometry extracted from stained ?CT data and is validated using results from stroboscopic digital holography measurements on the eardrum and LDV measurements on the columella footplate. This technique uses very short high-power laser pulses that are synchronized to the membrane's vibration phase to measure the dynamic response of the bird's eardrum to an incident acoustic stimulus. Vibration magnitude as well as phase relative to the sound wave can be deduced from the results, the latter being of great importance in the elastic characterization of the tympanic membrane. In this work, the setup and results from the optical measurements, as well as the properties and optimization of the finite element model are presented. Observed phase variations across the eardrum's surface on the holography results strongly suggest the presence of internal energy losses in the membrane due to damping. Therefore, a viscoelastic characterisation of the model based on a complex modulus with a loss factor is chosen. Optimal values for a number of essential material parameters are determined by applying inverse analysis techniques using the experimental results. The result is a realistic dynamic model of the avian middle ear that will be used in the future to enhance treatment of middle ear pathologies in humans.

Muyshondt, Pieter; De Greef, Daniël; Soons, Joris; Dirckx, Joris J. J.

2014-05-01

425

Giving High School Students a Research Grade Radio Telescope to Control; Motivational Results from Access to Real Scientific Tools  

NASA Astrophysics Data System (ADS)

Have you ever wondered what it might be like to place control of a six-story building in the hands of eager high school students? This past summer, the USNO 20m telescope at the National Radio Astronomy Observatory, Green Bank, WV was brought back online for just such a purpose. This telescope is equipped with an X-band receiver, capable of observing center frequencies from 8-10 GHz and is the first radio telescope accessible by students and observers through the SKYNET telescope network. Operated remotely with a queue-based system, students can now collect real radio data for any range of projects. This past summer, five lessons were written that were tailor-made for student exploration of radio astronomy. Each lesson explores various radio objects in the context of an action-packed sci-fi adventure. Some of the work required to bring the 20m online for student use will be discussed here, but the main focus of this presentation will be how this work has been received by the author’s own students in its first classroom application. Topics that are normally difficult to discuss with students in an inquiry-based classroom setting, such as HII regions, synchrotron radiation, lunar temperature profiles, and galactic supermassive black holes were addressed in the classroom using the lessons developed by the author for the 20m as well as data collected by students using the telescope via SKYNET.

Kohrs, Russell; Langston, G.; Heatherly, S.

2013-01-01

426

The Protein Information Management System (PiMS): a generic tool for any structural biology research laboratory  

PubMed Central

The techniques used in protein production and structural biology have been developing rapidly, but techniques for recording the laboratory information produced have not kept pace. One approach is the development of laboratory information-management systems (LIMS), which typically use a relational database schema to model and store results from a laboratory workflow. The underlying philosophy and implementation of the Protein Information Management System (PiMS), a LIMS development specifically targeted at the flexible and unpredictable workflows of protein-production research laboratories of all scales, is described. PiMS is a web-based Java application that uses either Postgres or Oracle as the underlying relational database-management system. PiMS is available under a free licence to all academic laboratories either for local installation or for use as a managed service. PMID:21460443

Morris, Chris; Pajon, Anne; Griffiths, Susanne L.; Daniel, Ed; Savitsky, Marc; Lin, Bill; Diprose, Jonathan M.; Wilter da Silva, Alan; Pilicheva, Katya; Troshin, Peter; van Niekerk, Johannes; Isaacs, Neil; Naismith, James; Nave, Colin; Blake, Richard; Wilson, Keith S.; Stuart, David I.; Henrick, Kim; Esnouf, Robert M.

2011-01-01

427

The Protein Information Management System (PiMS): a generic tool for any structural biology research laboratory.  

PubMed

The techniques used in protein production and structural biology have been developing rapidly, but techniques for recording the laboratory information produced have not kept pace. One approach is the development of laboratory information-management systems (LIMS), which typically use a relational database schema to model and store results from a laboratory workflow. The underlying philosophy and implementation of the Protein Information Management System (PiMS), a LIMS development specifically targeted at the flexible and unpredictable workflows of protein-production research laboratories of all scales, is described. PiMS is a web-based Java application that uses either Postgres or Oracle as the underlying relational database-management system. PiMS is available under a free licence to all academic laboratories either for local installation or for use as a managed service. PMID:21460443

Morris, Chris; Pajon, Anne; Griffiths, Susanne L; Daniel, Ed; Savitsky, Marc; Lin, Bill; Diprose, Jonathan M; da Silva, Alan Wilter; Pilicheva, Katya; Troshin, Peter; van Niekerk, Johannes; Isaacs, Neil; Naismith, James; Nave, Colin; Blake, Richard; Wilson, Keith S; Stuart, David I; Henrick, Kim; Esnouf, Robert M

2011-04-01

428

Discoveries and Breakthroughs Inside Science: A Tool To Help You Communicate Your Research Accurately, Effectively, and Extensively  

NASA Astrophysics Data System (ADS)

As a primary source of news, more people rely on local TV news than any other medium for their news and information. As a result, The American Geophysical Union has partnered with the American Institute of Physics in their production of Discoveries and Breakthroughs Inside Science (DBIS). DBIS is syndicated science news service that distributes 12, 90-second science news segments to over 80 local TV stations throughout the USA each month. Approximately 4 of these segments each month focus on research topics of interest to AGU members. Meet DBIS's senior science editor and learn about DBIS. Find out how you can improve your communication skills by participating in a DBIS segment or helping with DBIS production. Learn how the segment topics are chosen. Hear why the AGU got involved and how they work with the program.

Lorditch, E.

2006-12-01

429

Integration of Tsunami Analysis Tools into a GIS Workspace – Research, Modeling, and Hazard Mitigation efforts Within NOAA’s Center for Tsunami Research  

Microsoft Academic Search

\\u000a The National Oceanic and Atmospheric Administration’s \\u000a \\u000a (NOAA) Center for Tsunami Research \\u000a \\u000a \\u000a \\u000a \\u000a \\u000a \\u000a \\u000a (NCTR) uses geospatial data and GIS analysis techniques in support of building an accurate \\u000a \\u000a \\u000a tsunami forecasting system for the US Tsunami Warning Centers. \\u000a \\u000a \\u000a \\u000a The resulting forecast products can be integrated into applications and visualizations to assess hazard risk and provide mitigation\\u000a for US coastal communities ranging from small towns

Nazila Merati; Christopher Chamberlin; Christopher Moore; Vasily Titov; Tiffany C. Vance

430

Biogeography Recap Spatial models are one of our main tools  

E-print Network

differ from physiological limits. Understanding why can help us improve predictions ­ Distribution data · Altered precipitation · Rising CO2 Disturbance & habitat loss · Deforestation & degradation · Physical

Schweik, Charles M.

431

Supporting collaborative use of the diabetes population risk tool (DPoRT) in health-related practice: a multiple case study research protocol  

PubMed Central

Background Health policy makers have stated that diabetes prevention is a priority; however, the type, intensity, and target of interventions or policy changes that will achieve the greatest impact remains uncertain. In response to this uncertainty, the Diabetes Population Risk Tool (DPoRT) was developed and validated to estimate future diabetes risk based on routinely collected population data. To facilitate use of DPoRT, we partnered with regional and provincial health-related decision makers in Ontario and Manitoba, Canada. Primary objectives include: i) evaluate the effectiveness of partnerships between the research team and DPoRT users; ii) explore strategies that facilitate uptake and overcome barriers to DPoRT use; and iii) implement and evaluate the knowledge translation approach. Methods This protocol reflects an integrated knowledge translation (IKT) approach and corresponds to the action phase of the Knowledge-to-Action (KtoA) framework. Our IKT approach includes: employing a knowledge brokering team to facilitate relationships with DPoRT users (objective 1); tailored training for DPoRT users; assessment of barriers and facilitators to DPoRT use; and customized dissemination strategies to present DPoRT outputs to decision maker audiences (objective 2). Finally, a utilization-focused evaluation will assess the effectiveness and impact of the proposed KtoA process for DPoRT application (objective 3). This research design utilizes a multiple case study approach. Units of analyses consist of two public health units, one provincial health organization, and one provincial knowledge dissemination team whereby we will connect with multiple regional health authorities. Evaluation will be based on analysis of both quantitative and qualitative data collected from passive (e.g., observer notes) and active (e.g., surveys and interviews) methods. Discussion DPoRT offers an innovative way to make routinely collected population health data practical and meaningful for diabetes prevention planning and decision making. Importantly, we will evaluate the utility of the KtoA cycle for a novel purpose – the application of a tool. Additionally, we will evaluate this approach in multiple diverse settings, thus considering contextual factors. This research will offer insights into how knowledge translation strategies can support the use of population-based risk assessment tools to promote informed decision making in health-related settings. PMID:24655716

2014-01-01

432

Programmer-Friendly Refactoring Tools  

Microsoft Academic Search

Tools that perform semi-automated refactoring are currently under-utilized by programmers. If more programmers adopted refactoring tools, software projects could make enormous productivity gains. However, as more advanced refactoring tools are designed, a great chasm widens between how the tools must be used and how programmers want to use them. The proposed research will bridge this chasm by exposing usability guidelines

Emerson Murphy-Hill

433

Forest management under changing climate conditions: Is timing a tool for Sustainable Forest Management? Relevant questions for research development  

NASA Astrophysics Data System (ADS)

Change of climate conditions influence energy fluxes applicable to forest ecosystems. These affect cycles of nutrients and materials, primary productivity of the ecosystem, biodiversity, ecological functionality and, consequently, carbon equilibria of the forest ecosystem. Temporal factors influence physical, biological, ecological, and climatic processes and functions. For example, seasonality, cycles, periodicity, and trends in climate variables; tree growth, forest growth, and forest metabolic activities (i.e., photosynthesis and respiration) are commonly known to be time-related. In tropical forests, the impacts of changing climate conditions may exceed temperature and/or precipitation thresholds critical to forest tree growth or health. Historically, forest management emphasises growth rates and financial returns as affected by species and site. Until recently, the influence of climate variability on growth dynamics has not been influential in forest planning and management. Under this system, especially in climatic and forest regions where most of species are stenoecious, periodical wood harvesting may occur in any phase of growth (increasing, decreasing, peak, and trough). This scenario presents four main situations: a) harvesting occurs when the rate of growth is decreasing: future productivity is damaged; the minimum biomass capital may be altered, and CO2 storage is negatively affected; b) harvesting occurs during a trough of the rate of growth: the minimum biomass capital necessary to preserve the resilience of the forest is damaged; the damage can be temporary (decades) or permanent; CO2 storage capacity is deficient - which may be read as an indirect emission of CO2 since the balance appears negative; c) harvesting occurs when the rate of growth is increasing: the planned wood mass can be used without compromising the resilience and recovery of the forest; CO2 storage remains increasing; d) harvesting occurs during a peak period of growth: the wood mass harvested can be even higher than planned, and the rate of CO2 storage can be above the average. A real risk for SFM under changing climatic conditions is that negative effects may be amplified; critical thresholds of temperature and/or rainfall for tree growth and stress may be exceeded with impacts on growth response, resilience, and CO2 balance that are not completely known. Furthermore, temporal changes in silvicultural and harvesting operations may lead to increased carbon emissions. Under this scenario and the consequent risks to SFM forestry operations should be planned or scheduled in periods when climate variables influencing tree growth and stress are within the relative thresholds. In this way, silvicultural operations and harvesting are going to be optimised to climate variability and forest growth responses, rather than just forest timber production.

D'Aprile, Fabrizio; McShane, Paul; Tapper, Nigel

2013-04-01

434

Google Tools in the Classroom  

NASA Astrophysics Data System (ADS)

The Maine Learning Technology Initiative provides every seventh and eighth grade student in the state with MacBook laptop computers. Limitless education possibilities exist with the inclusion of Google Tools and laptops as learning tools in our modern classrooms. Google Applications allow students to create documents, spreadsheets, charts, graphs, forms, and presentations and easily allows the sharing of information with their fellow classmates and teachers. These applications invite the use of inquiry and critical thinking skills, collaboration among peers, and subject integration to teach students crucial concepts. The benefits for teachers extend into the realm of using Google sites to easily create a teacher website and blog to upload classroom information and create a communication connection for parents and students as well as collaborations between the teachers and University researchers and educators. Google Applications further enhances the possibilities for learning, sharing a wealth of information, and enhancing communication inside and outside of the classroom.

Albee, E. M.; Koons, P. O.; Schauffler, M.; Zhu, Y.; Segee, B. E.

2009-12-01

435

Country clustering applied to the water and sanitation sector: a new tool with potential applications in research and policy.  

PubMed

The fields of global health and international development commonly cluster countries by geography and income to target resources and describe progress. For any given sector of interest, a range of relevant indicators can serve as a more appropriate basis for classification. We create a new typology of country clusters specific to the water and sanitation (WatSan) sector based on similarities across multiple WatSan-related indicators. After a literature review and consultation with experts in the WatSan sector, nine indicators were selected. Indicator selection was based on relevance to and suggested influence on national water and sanitation service delivery, and to maximize data availability across as many countries as possible. A hierarchical clustering method and a gap statistic analysis were used to group countries into a natural number of relevant clusters. Two stages of clustering resulted in five clusters, representing 156 countries or 6.75 billion people. The five clusters were not well explained by income or geography, and were distinct from existing country clusters used in international development. Analysis of these five clusters revealed that they were more compact and well separated than United Nations and World Bank country clusters. This analysis and resulting country typology suggest that previous geography- or income-based country groupings can be improved upon for applications in the WatSan sector by utilizing globally available WatSan-related indicators. Potential applications include guiding and discussing research, informing policy, improving resource targeting, describing sector progress, and identifying critical knowledge gaps in the WatSan sector. PMID:24054545

Onda, Kyle; Crocker, Jonny; Kayser, Georgia Lyn; Bartram, Jamie

2014-03-01

436

The main cubioid  

NASA Astrophysics Data System (ADS)

The connectedness locus in the parameter space of quadratic polynomials is called the Mandelbrot set. A good combinatorial model of this set is due to Thurston. By definition, the principal hyperbolic domain of the Mandelbrot set consists of parameter values, for which the corresponding quadratic polynomials have an attracting fixed point. The closure of the principal hyperbolic domain of the Mandelbrot set is called the main cardioid. Its topology is completely described by Thurston's model. Less is known about the connectedness locus in the parameter space of cubic polynomials. In this paper, we discuss cubic analogues of the main cardioid and establish relationships between them.

Blokh, Alexander; Oversteegen, Lex; Ptacek, Ross; Timorin, Vladlen

2014-08-01

437

Possible biomedical applications and limitations of a variable-force centrifuge on the lunar surface: A research tool and an enabling resource  

NASA Technical Reports Server (NTRS)

Centrifuges will continue to serve as a valuable research tool in gaining an understanding of the biological significance of the inertial acceleration due to gravity. Space- and possibly lunar-based centrifuges will play a significant and enabling role with regard to the human component of future lunar and martian exploration, both as a means of accessing potential health and performance risks and as a means of alleviating these risks. Lunar-based centrifuges could be particularly useful as part of a program of physiologic countermeasures designed to alleviate the physical deconditioning that may result from prolonged exposure to a 1/6-g environment. Centrifuges on the lunar surface could also be used as part of a high-fidelity simulation of a trip to Mars. Other uses could include crew readaptation to 1 g, waste separation, materials processing, optical mirror production in situ on the Moon, and laboratory specimen separation.

Cowing, Keith L.

1992-01-01

438

Validation of electrical discharge machining electrodes made with rapid tooling technologies  

Microsoft Academic Search

Rapid tooling technologies allow tools and moulds to be manufactured in a short time and with complex geometry. The main aim of this research is to develop new electrical discharge machining (EDM) electrode testing and manufacturing by applying rapid prototyping (RP) and electroforming technologies. Copper electroformed shells allow complex electrodes to be obtained with a high dimensional precision and with

M. Monzón; A. N. Benítez; M. D. Marrero; N. Hernández; P. Hernández; J. Aisa

2008-01-01

439

MAINE SCHOOLS AND LIBRARIES  

EPA Science Inventory

SCHLIB shows point locations of libraries and educational institutions in Maine at 1:24,000 scale. Colleges, universities, technical colleges, high schools, middle schools, elementary schools, kindergarten/sub-primary and other special schools are included. The data was developed...

440

Maine Dance Curriculum Guide.  

ERIC Educational Resources Information Center

This curriculum guide is designed to support those in Maine who wish to establish or enhance dance education in any educational areas and at elementary or secondary levels. A preface describes the state's dance heritage. An introduction argues for the importance of dance education. The next section addresses pedagogy and explains how to create and…

Grindel, Susan; And Others

441

COLDSPRINGCREEK MAIN STREET WEST  

E-print Network

.................................... 43 David Braley Athletic Centre.... 54 Divinity College............................ 17 Dramatic Arts MAIN STREET WEST COLLEGE CRESCENT COOTESDRIVE WESTAWAY ROAD SCHOLAR'S ROAD STEARN DRIVE Entrance Pay Stations Short Term Parking - Pay and Display Campus Shuttle Bus Service Go Bus Stop A-Q CAMPUS

Thompson, Michael

442

COLDSPRINGCREEK MAIN STREET WEST  

E-print Network

....................................43 David Braley Athletic Centre ....54 Divinity College............................17 Dramatic Arts 37 MAIN STREET WEST COLLEGE CRESCENT COOTESDRIVE WESTAWAY ROAD SCHOLAR'S ROAD STEARN DRIVE EntranceCampus LEGEND McMaster University Entrance Security and Parking Services Parking Lot Location Pay Stations Short

Haykin, Simon

443

Main Course Beef Lasagne  

E-print Network

with lemon and free range egg mayonnaise Mediterranean Quorn and Garlic Pie A ragu of roasted Mediterranean vegetables and Quorn topped with garlic bread slices Served with Sautéed New Potatoes or Penne Pasta Sweet Corn & Garlic Bread Salad Bar Should you wish to have salad as your main meal please see the choice

Bristol, University of

444

Tool steels. 5. edition  

SciTech Connect

The revision of this authoritative work contains a significant amount of new informati