Sample records for mama tras tratamiento

  1. Tratamiento con fulvestrant en mujeres posmenopáusicas con cáncer de mama avanzado tras tratamiento hormonal previo

    Microsoft Academic Search

    Virginia Martínez Marín; Andrés J. Muñoz Martín; M. Carmen Viñuela Benéitez; Pilar García Alfonso; Antonio Alonso Muñoz; Gumersindo Pérez Manga

    2009-01-01

    Background and objectiveFulvestrant (Flv) is a pure antiestrogen without agonist activity. Flv is effective as second line treatment in postmenopausal women with advanced breast cancer after tamoxifen.

  2. Cáncer de seno (mama)

    Cancer.gov

    Información del Instituto Nacional del Cáncer sobre el tratamiento, la prevención, la genética, las causas y los exámenes de detección del cáncer de seno (mama), así como referencias a estudios clínicos, investigación, estadísticas y temas relacionados.

  3. STIS-09 MAMA Darks

    Microsoft Academic Search

    Charles Proffitt

    2001-01-01

    Obtain twice-weekly dark frames, as in the corresponding calibration program {program 8843 in Cycle 9}. Construct standard calibration refrence files for use in pipeline reduction of SMOV3B data. Transition to analogous calibration program when normal science operation with the MAMA detectors begins.

  4. STIS-09 MAMA Darks

    NASA Astrophysics Data System (ADS)

    Proffitt, Charles

    2001-07-01

    Obtain twice-weekly dark frames, as in the corresponding calibration program {program 8843 in Cycle 9}. Construct standard calibration refrence files for use in pipeline reduction of SMOV3B data. Transition to analogous calibration program when normal science operation with the MAMA detectors begins.

  5. Conferencia de Consenso sobre la braquiterapia en cáncer de mama en estadios iniciales

    Microsoft Academic Search

    F. Guedea; L. Arribas; F. Casquero; C. Cinos; V. Crispin; A. Gracia; J. L. Guinot; I. Monteiro-Grillo; V. Munoz; J. Pera; A. Polo; L. Linares; H. Marsiglia; J. J. Mazeron

    2003-01-01

    Resumen  Existe una controversia desde hace décadas sobre el papel de la sobredosis después de la radioterapia externa en el tratamiento\\u000a conservador de cáncer de mama inicial. En el caso de comparar la supervivencia y el control local de un tratamiento conservador\\u000a frente a la mastectomía, existen en la literatura 5 estudios randomizados1–5 y un metaanálisis6 que demuestran que la radioterapia

  6. MAMA- User Feedback and Training Summary

    SciTech Connect

    Porter, Reid B. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Ruggiero, Christy E. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2014-05-21

    This document describes the current state of the MAMA (Morphological Analysis of Materials) software user identified bugs, issues, and requests for improvements. It also lists Current users and current training methods.

  7. MAMA Software Features: Quantification Verification Documentation-1

    SciTech Connect

    Ruggiero, Christy E. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Porter, Reid B. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2014-05-21

    This document reviews the verification of the basic shape quantification attributes in the MAMA software against hand calculations in order to show that the calculations are implemented mathematically correctly and give the expected quantification results.

  8. Instantánea del cáncer de seno (mama)

    Cancer.gov

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre el cáncer de seno (mama); así como ejemplos de actividades del NCI y adelantos en la investigación de este tipo de cáncer.

  9. MAMA detector systems - A status report

    NASA Technical Reports Server (NTRS)

    Timothy, J. Gethyn; Morgan, Jeffrey S.; Slater, David C.; Kasle, David B.; Bybee, Richard L.

    1989-01-01

    Third-generation, 224 x 960 and 360 x 1024-pixel multianode microchannel (MAMA) detectors are under development for satellite-borne FUV and EUV observations, using pixel dimensions of 25 x 25 microns. An account is presently given of the configurations, modes of operation, and recent performance data of these systems. At UV and visible wavelengths, these MAMAs employ a semitransparent, proximity-focused photocathode structure. At FUV and EUV wavelengths below about 1500 A, opaque alkali-halide photocathodes deposited directly on the front surface of the MCP furnish the best detective quantum efficiencies.

  10. "Mama's Boy; Preacher's Son": A Memoir

    ERIC Educational Resources Information Center

    Whitlock, Reta Ugena

    2010-01-01

    "Mama's Boy; Preacher's Son" is Kevin Jennings's autobiographical account of growing up gay in the Southern United States. In his memoir, Jennings shares formative experiences relating to his impoverished childhood and his career as teacher and social activist. His rich description of the influence of family relationships on his personal and…

  11. The STIS MAMA status: Current detector performance

    NASA Technical Reports Server (NTRS)

    Danks, A. C.; Joseph, C.; Bybee, R.; Argebright, V.; Abraham, J.; Kimble, R.; Woodgate, B.

    1992-01-01

    The STIS (Space Telescope Imaging Spectrograph) is a second generation Hubble instrument scheduled to fly in 1997. Through a variety of modes, the instrument will provide spectral resolutions from R approximately 50 in the objective spectroscopy mode to 100,000 in the high resolution echelle mode in the wavelength region from 115 to 1000 nm. In the UV the instrument employs two MAMA (Multimode Anode Microchannel plate Arrays) 1024 by 1024 pixel detectors, which provide high DQE (Detective Quantum Efficiency), and good dynamic range and resolution. The current progress and performance of these detectors are reported, illustrating that the technology is mature and that the performance is very close to flight requirements.

  12. Imaging MAMA detector systems. [Multi-Anode Microchannel Array

    NASA Technical Reports Server (NTRS)

    Slater, David C.; Timothy, J. G.; Morgan, Jeffrey S.; Kasle, David B.

    1990-01-01

    Imaging multianode microchannel array (MAMA) detector systems with 1024 x 1024 pixel formats have been produced for visible and UV wavelengths; the UV types employ 'solar blind' photocathodes whose detective quantum efficiencies are significantly higher than those of currently available CCDs operating at far-UV and EUV wavelengths. Attention is presently given to the configurations and performance capabilities of state-of-the-art MAMA detectors, with a view to the development requirements of the hybrid electronic circuits needed for forthcoming spacecraft-sensor applications. Gain, dark noise, uniformity, and dynamic range performance data are presented for the curved-channel 'chevron', 'Z-plate', and helical-channel high gain microchannel plate configurations that are currently under evaluation with MAMA detector systems.

  13. Teacher Reporting Attitudes Scale (TRAS): Confirmatory and Exploratory Factor Analyses with a Malaysian Sample

    ERIC Educational Resources Information Center

    Choo, Wan Yuen; Walsh, Kerryann; Chinna, Karuthan; Tey, Nai Peng

    2013-01-01

    The Teacher Reporting Attitude Scale (TRAS) is a newly developed tool to assess teachers' attitudes toward reporting child abuse and neglect. This article reports on an investigation of the factor structure and psychometric properties of the short form Malay version of the TRAS. A self-report cross-sectional survey was conducted with 667…

  14. Influence of formulation ratio of the plant components on the antimalarial properties of MAMA decoction.

    PubMed

    Odediran, Samuel Akintunde; Elujoba, Anthony Adebolu; Adebajo, Adeleke Clement

    2014-05-01

    Mangifera indica, Alstonia boonei, Morinda lucida and Azadirachta indica (MAMA) decoction, commonly prepared and used in Nigeria from 1:1:1:1 ratio of Mangifera indica L. (Anacardiaceae), Alstonia boonei De Wild (Apocynaceae), Morinda lucida Benth (Rubiaceae), and Azadirachta indica A. Juss (Meliaceae) leaves, plus four new variants of this combination were subjected to three in vivo antimalarial test models using chloroquine-sensitive Plasmodium berghei berghei to determine the most active under each of the test models. Using the original formulation, MAMA (1:1:1:1) which gave ED50 and ED90 of 101.54±2.95 and 227.18±2.95, respectively, as reference for comparison, MAMA-1 (1:2:2:2), with 79.58±1.30 and 170.98±1.30, gave significantly (p<0.05) higher survival at 85 and 340 mg/kg when 80 % of the mice survived for 15.6 and 17.8 days, respectively, while MAMA-2 (2:1:2:2), with 83.57±1.93 and 164.23±1.93, gave comparable survival except at 170 mg/kg with 60 % survivors for 12 days. MAMA-1 and MAMA-2 were the best curative formulations with MAMA-1 giving additional prophylactic activity. MAMA-3 (2:2:2:1) with 98.70±0.91 and 220.17±0.91, gave comparable (p>0.05) survival at 85 mg/kg with 60 % survival for 13.2 days and significantly higher survival at 42.5 mg/kg for 17 days with 40 % survival. Both MAMA and MAMA-3 were the best chemosuppressive formulations plus additional curative activities. MAMA-4 (1:1:2:2), the best prophylactic formulation with 94.87±2.43 and 201.20±2.43 gave significantly higher (p<0.05) survival at all doses except at 21.25 mg/kg which gave 60 % survival up to 10 days. Thus, the antimalarial therapy desired, following appropriate diagnosis, whether prophylactic, chemosuppressive or curative would determine which of the MAMA decoction formulations to be prescribed. This phenomenon of formulary optimization may also be applied to other pharmacological activities. PMID:24658658

  15. Características y tratamiento del trastorno obsesivo resistente al tratamiento

    Microsoft Academic Search

    Daniel Navarro Bayón

    Este artículo presenta el perfil clínico del trastorno obsesivo resistente a las intervenciones terapéuti- cas de primera elección (cognitivo-conductuales y farmacológicas). No existen criterios claros en la definición del concepto de resistencia al tratamiento para los pacientes obsesivos. Para considerar a un paciente como resistente se pueden considerar los siguientes criterios: el paciente ha recibido un mí- nimo de dos

  16. Full-field sensitivity and its time-dependence for the STIS CCD and MAMAs

    NASA Astrophysics Data System (ADS)

    Roman-Duval, Julia; Proffitt, Charles

    2013-07-01

    The three STIS detectors - CCD, NUV-MAMA, FUV-MAMA - are subject to temperature- and time-dependent sensitivity changes. These temporal sensitivity variations are cal- ibrated as part of routine calibration monitoring programs, and corrected for in the standard CALSTIS pipeline. In order to determine whether the correction algorithms, developed based on spectroscopic observations prior to the 2004 failure of STIS, are adequate for pre- and post-SM4 STIS imaging data, we examine the photometry of stan- dard stellar fields (NGC5139 for the CCD, NGC6681 for the MAMAs) obtained between 1997 and 2012 as part of the routine full-field sensitivity calibration programs. For the CCD, we include a correction for CTE effects. We find statistically significant residual temporal variations in the full-field sensitivity of 0.5 mmag/year, 0.04 mmag/year, and 0.54 mmag/year for the CCD, NUV-MAMA, and FUV-MAMA respectively. However, these residual trends are small: they do not incur flux changes exceeding 1% over a 15 year time period.

  17. Self-recognition mechanism of MamA, a magnetosome-associated TPR-containing protein, promotes complex assembly.

    PubMed

    Zeytuni, Natalie; Ozyamak, Ertan; Ben-Harush, Kfir; Davidov, Geula; Levin, Maxim; Gat, Yair; Moyal, Tal; Brik, Ashraf; Komeili, Arash; Zarivach, Raz

    2011-08-16

    The magnetosome, a biomineralizing organelle within magnetotactic bacteria, allows their navigation along geomagnetic fields. Magnetosomes are membrane-bound compartments containing magnetic nanoparticles and organized into a chain within the cell, the assembly and biomineralization of magnetosomes are controlled by magnetosome-associated proteins. Here, we describe the crystal structures of the magnetosome-associated protein, MamA, from Magnetospirillum magneticum AMB-1 and Magnetospirillum gryphiswaldense MSR-1. MamA folds as a sequential tetra-trico-peptide repeat (TPR) protein with a unique hook-like shape. Analysis of the MamA structures indicates two distinct domains that can undergo conformational changes. Furthermore, structural analysis of seven crystal forms verified that the core of MamA is not affected by crystallization conditions and identified three protein-protein interaction sites, namely a concave site, a convex site, and a putative TPR repeat. Additionally, relying on transmission electron microscopy and size exclusion chromatography, we show that highly stable complexes form upon MamA homooligomerization. Disruption of the MamA putative TPR motif or N-terminal domain led to protein mislocalization in vivo and prevented MamA oligomerization in vitro. We, therefore, propose that MamA self-assembles through its putative TPR motif and its concave site to create a large homooligomeric scaffold which can interact with other magnetosome-associated proteins via the MamA convex site. We discuss the structural basis for TPR homooligomerization that allows the proper function of a prokaryotic organelle. PMID:21784982

  18. Preliminary results of primary screening for breast cancer with the Mama Program

    Microsoft Academic Search

    Gisela Gästrin

    1993-01-01

    Summary In 1972 a comprehensive BSE screening strategy for the early detection of breast cancer, the “Mama Program Screening” (MPS), was developed in Finland by the author on the initiative of women's organizations. The program consists of a) initial information about the facilities of the program and BSE-performance, b) prospective surveillance of the BSE-behaviour of complying women, who use a

  19. EFICACIA DE LA TERAPIA DE GRUPO EN CÁNCER DE MAMA: VARIACIONES EN LA CALIDAD DE VIDA

    Microsoft Academic Search

    Eva Rodríguez

    2004-01-01

    La terapia de grupo es una modalidad de intervención cada vez más utilizada con pacien- tes oncológicos. El presente estudio aporta evi- dencia de cómo una intervención psicológica en grupo mejora la calidad de vida de las pacien- tes con cáncer de mama. Se utilizó una muestra de 142 pacientes que solicitaban ayuda psico- lógica en grupo en la Asociación

  20. Neoplasias mielodisplásicas o mieloproliferativas: Tratamiento (PDQ®)

    Cancer.gov

    Resumen de información revisada por expertos acerca del tratamiento de las neoplasias mielodisplásicas o mieloproliferativas, incluso las leucemias mielomonocíticas crónicas o juveniles, y la LMC atípica.

  1. MamA as a Model Protein for Structure-Based Insight into the Evolutionary Origins of Magnetotactic Bacteria

    PubMed Central

    Lefèvre, Christopher T.; Arnoux, Pascal; Baran, Dror; Shtein, Zvi; Davidov, Geula; Zarivach, Raz

    2015-01-01

    MamA is a highly conserved protein found in magnetotactic bacteria (MTB), a diverse group of prokaryotes capable of navigating according to magnetic fields – an ability known as magnetotaxis. Questions surround the acquisition of this magnetic navigation ability; namely, whether it arose through horizontal or vertical gene transfer. Though its exact function is unknown, MamA surrounds the magnetosome, the magnetic organelle embedding a biomineralised nanoparticle and responsible for magnetotaxis. Several structures for MamA from a variety of species have been determined and show a high degree of structural similarity. By determining the structure of MamA from Desulfovibrio magneticus RS-1 using X-ray crystallography, we have opened up the structure-sequence landscape. As such, this allows us to perform structural- and phylogenetic-based analyses using a variety of previously determined MamA from a diverse range of MTB species across various phylogenetic groups. We found that MamA has remained remarkably constant throughout evolution with minimal change between different taxa despite sequence variations. These findings, coupled with the generation of phylogenetic trees using both amino acid sequences and 16S rRNA, indicate that magnetotaxis likely did not spread via horizontal gene transfer and instead has a significantly earlier, primordial origin. PMID:26114501

  2. Magnetosome vesicles are present before magnetite formation, and MamA is required for their activation

    PubMed Central

    Komeili, Arash; Vali, Hojatollah; Beveridge, Terrance J.; Newman, Dianne K.

    2004-01-01

    Bacterial magnetosomes are intracellular compartments that house highly ordered magnetite crystals. By using Magnetospirillum sp. AMB-1 as a model system, we show that magnetosome vesicles exist in the absence of magnetite, biomineralization of magnetite proceeds simultaneously in multiple vesicles, and biomineralization proceeds from the same location in each vesicle. The magnetosome-associated protein, MamA, is required for the formation of functional magnetosome vesicles and displays a dynamic subcellular localization throughout the growth cycle of magnetotactic bacteria. Together, these results suggest that the magnetosome precisely coordinates magnetite biomineralization and can serve as a model system for the study of organelle biogenesis in noneukaryotic cells. PMID:15004275

  3. Patología postquirúrgica del cáncer de mama. Propuesta de subproceso y desarrollo de una unidad de tratamiento rehabilitador en el contexto sanitario andaluz

    Microsoft Academic Search

    A. Galván; Y. Pons; C. Echevarría; T. Ibáñez

    2008-01-01

    In recent years, the Public Health Care Administration of Andalusia has developed health care programs to improve care programs aimed at structuring, improving and encouraging user care\\/patient care in specific diseases due to their social and economic incidence, repercussions and costs. The role of the specialist in Physical Medicine and Rehabilitation is not always well defined within the care algorithms

  4. Investigación sobre el tratamiento de cáncer

    Cancer.gov

    La Iniciativa de Respuestas Excepcionales (Exceptional Responders Initiative), un estudio que investiga los factores moleculares de los tumores en pacientes de cáncer que responden en forma excepcional al tratamiento con medicamentos, se inició hoy bajo la guía del Instituto Nacional del Cáncer (NCI). Los científicos tratarán de identificar en los tumores las características moleculares que predicen si un medicamento o una clase de medicamento en particular será beneficioso o no.

  5. El uso de la neuromodulación para el tratamiento del temblor

    PubMed Central

    Bendersky, Damián; Ajler, Pablo; Yampolsky, Claudio

    2014-01-01

    Introducción: El temblor puede ser un desorden incapacitante y el tratamiento de primera línea para estos pacientes es farmacológico. Sin embargo, este tratamiento puede llevar a una reducción satisfactoria del temblor en sólo el 50% de los pacientes con temblor esencial. La talamotomía era el tratamiento de elección para el temblor refractario al tratamiento médico hasta que comenzó a utilizarse la estimulación cerebral profunda (ECP) del núcleo ventral intermedio (Vim) del tálamo. En la actualidad, raramente se realiza la talamotomía. Métodos: Este artículo es una revisión no sistemática de las indicaciones, resultados, parámetros de programación y técnica quirúrgica de la ECP del Vim para el tratamiento del temblor. Resultados: Aunque los resultados clínicos son similares usando la talamotomía o la ECP del Vim, la primera causa más efectos adversos que la última. Además, la ECP puede ser usada bilateralmente, mientras que la talamotomía tiene un alto riesgo de causar disartria cuando se realiza de ambos lados. La ECP del Vim logró una adecuada mejoría del temblor en varias series de pacientes con temblor causado por temblor esencial, enfermedad de Parkinson o esclerosis múltiple. Además del Vim, hay otros blancos que están siendo usados por varios autores, tales como la zona incerta y las radiaciones prelemniscales. Conclusión: La ECP del Vim es un tratamiento útil para el temblor incapacitante refractario al tratamiento médico. Es esencial realizar una precisa selección de pacientes, así como utilizar una técnica quirúrgica correcta. Aún se desconoce el mejor blanco estereotáctico para el temblor, aunque el Vim es el más usado. PMID:25165613

  6. A common structure for concepts of individuals, stuffs, and real kinds: more Mama, more milk, and more mouse.

    PubMed

    Millikan, R G

    1998-02-01

    Concepts are highly theoretical entities. One cannot study them empirically without committing oneself to substantial preliminary assumptions. Among the competing theories of concepts and categorization developed by psychologists in the last thirty years, the implicit theoretical assumption that what falls under a concept is determined by description ("descriptionism") has never been seriously challenged. I present a nondescriptionist theory of our most basic concepts, "substances," which include (1) stuffs (gold, milk), (2) real kinds (cat, chair), and (3) individuals (Mama, Bill Clinton, the Empire State Building). On the basis of something important that all three have in common, our earliest and most basic concepts of substances are identical in structure. The membership of the category "cat," like that of "Mama," is a natural unit in nature, to which the concept "cat" does something like pointing, and continues to point despite large changes in the properties the thinker represents the unit as having. For example, large changes can occur in the way a child identifies cats and the things it is willing to call "cat" without affecting the extension of its word "cat." The difficulty is to cash in the metaphor of "pointing" in this context. Having substance concepts need not depend on knowing words, but language interacts with substance concepts, completely transforming the conceptual repertoire. I will discuss how public language plays a crucial role in both the acquisition of substance concepts and their completed structure. PMID:10097011

  7. Anticipated uncertainty budgets of PRARETIME and T2L2 techniques as applied to ExTRAS

    NASA Technical Reports Server (NTRS)

    Thomas, Claudine; Wolf, Peter; Uhrich, Pierre J. M.; Schaefer, W.; Nau, H.; Veillet, Christian

    1995-01-01

    The Experiment on Timing Ranging and Atmospheric Soundings, ExTRAS, was conceived jointly by the European Space Agency, ESA, and the Russian Space Agency, RSA. It is also designated the 'Hydrogen-maser in Space/Meteor-3M project'. The launch of the satellite is scheduled for early 1997. The package, to be flown on board a Russian meteorological satellite includes ultra-stable frequency and time sources, namely two active and auto-tuned hydrogen masers. Communication between the on-board hydrogen masers and the ground station clocks is effected by means of a microwave link using the modified version for time transfer of the Precise Range And Range-rate Equipment, PRARETIME, technique, and an optical link which uses the Time Transfer by Laser Link, T2L2, method. Both the PRARETIME and T2L2 techniques operate in a two-directional mode, which makes it possible to carry out accurate transmissions without precise knowledge of the satellite and station positions. Due to the exceptional quality of the on-board clocks and to the high performance of the communication techniques with the satellite, satellite clock monitoring and ground clocks synchronization are anticipated to be performed with uncertainties below 0.5 ns (1 sigma). Uncertainty budgets and related comments are presented.

  8. Satellite test of the isotropy of the one-way spe ed of light using ExTRAS

    NASA Technical Reports Server (NTRS)

    Wolf, Peter

    1995-01-01

    A test of the second postulate of special relativity, the universality of the speed of light, using the ExTRAS (Experiment on Timing Ranging and Atmospheric Sounding) payload to be flown on board a Russian Meteor-3M satellite (launch date January 1997) is proposed. The propagation time of a light signal transmitted from one point to another without reflection would be measured directly by comparing the phases of two hydrogen maser clocks, one on board and one on the ground, using laser or microwave time transfer systems. An estimated uncertainty budget of the proposed measurements is given, resulting in an expected sensitivity of the experiment of delta c/c is less than 8xl0(exp -10) which would be an improvement by a factor of approximately 430 over previous direct measurements and by a factor of approximately 4 over the best indirect measurement. The proposed test would require no equipment additional to what is already planned and so is of inherently low-cost. It could be carried out by anyone having access to a laser or microwave ground station and a hydrogen maser.

  9. PAQUETES TECNOLÓGICOS PARA EL TRATAMIENTO DE DATOS EN INVESTIGACIÓN EN

    Microsoft Academic Search

    EDUCACIÓN MATEMÁTICA

    En este artículo se presentan algunas aplicaciones de paquetes tecnológicos para el tratamiento y análisis de datos en educación matemática. Para tal fin se efectúa un estudio documental, a partir del cual se clasifican los paquetes tecnológicos de acuerdo a diversos criterios de autores como Algarabel y Sanmartín, Valles, Buendía, Colás y Hernández. Se toma en cuenta los tipos de

  10. Base molecular de la fenilcetonuria: Del genotipo al tratamiento clínico

    Microsoft Academic Search

    Johannes Zschocke

    2010-01-01

    ResumenEn la era de la detección sistemática neonatal y el tratamiento presintomático de individuos con fenilcetonuria, la definición de la enfermedad ha variado desde una serie de síntomas clínicos observados en pacientes no tratados, hasta una predisposición hereditaria necesitada de una intervención alimentaria para evitar el daño cerebral y el deterioro intelectual. En consecuencia, el análisis de correlaciones entre genotipo

  11. PRUEBA CLÍNICA INTELIGENTE PDNR-CA1: HACIA LA PREVENCIÓN Y DETECCIÓN PRECOZ DEL CÁNCER DE MAMA, COMO SOPORTE CLÍNICO PARA LA TOMA DE DECISIONES PRUEBA CLÍNICA INTELIGENTE PDNR-CA1: HACIA LA PREVENCIÓN Y DETECCIÓN PRECOZ DEL CÁNCER DE MAMA, COMO SOPORTE CLÍNICO PARA LA TOMA DE DECISIONES

    Microsoft Academic Search

    Héctor Julio; Díaz Vargas

    La relatividad del comportamiento celular y su expresión molecular, obedecen a la obligada interacción con leyes químicas y físicas, en un modelo biológico multifactorial- multivariable. Por esta razón para poder rastrear in vivo el desarrollo pre-neoplasico y la aparición de las primeras células neoplasicas en mama, se ha diseñado la prueba inteligente PDNR-CA1 capaz de cuantificar el nivel de riesgo

  12. Programa de análisis molecular para la elección de tratamientos del NCI (NCI-MATCH)

    Cancer.gov

    Información sobre el Programa de análisis molecular para la elección de tratamientos del NCI (NCI-MATCH), en el cual los investigadores examinarán tejidos de tumor de pacientes con tumores sólidos y linfomas avanzados que han dejado de responder al tratamiento.

  13. Fumar durante el tratamiento de cáncer–para profesionales de salud (PDQ®)

    Cancer.gov

    Resumen de información revisada por expertos acerca de la influencia de seguir fumando sobre el tratamiento del cáncer y el riesgo de segundos cánceres. Se mencionan las intervenciones que estimulan dejar el hábito de fumar.

  14. Cánceres poco comunes en la niñez: Tratamiento–para profesionales de salud (PDQ®)

    Cancer.gov

    Resumen de información revisada por expertos acerca del tratamiento de los cánceres poco comunes en la niñez como los cánceres de la cabeza y el cuello, el tórax, el abdomen, el aparato reproductor, la piel y otros.

  15. Crystal Packin' Mama

    NSDL National Science Digital Library

    2012-04-10

    In this activity, learners investigate the basic crystal structures that metal atoms form. Learners construct models of crystals using Styrofoam balls and learn about hexagonal close packing (HCP) and face centered cubic (FCC) packing.

  16. Tratamiento psicológico de la cefalea. Predicción de la mejoría en un acercamiento activo-pasivo

    Microsoft Academic Search

    María I. Comeche; Miguel A. Vallejo; Marta I. Díaz

    Este trabajo pretende estudiar las va ri ables que pudieran predecir la eficacia de dos acercamientos dis- tintos al tratamiento psicológico de las cefaleas pr i m a ri a s : en uno se potencia la implicación activa del paciente y su implicación pasiva en el otro. 21 pacientes de cefalea fueron asignados a 2 grupos. El pri- mer

  17. Variaciones en el tratamiento de las sibilantes Inconsistencia en el seseo sevillano: Un enfoque sociolingüístico

    E-print Network

    Gonzalez-Bueno, Manuela

    1993-04-01

    linguisticos. Una de estas causas, muy importante, a mi en- tender, es el tratamiento que los rasgos dialectales andaluces reciben en los libros de texto de EGB (Ensenanza General Basica, equivalents a la ensenanza primaria) y BUP (Bachiller Unificado... Polivalente, equivalente a la ensenanza secundaria). A causa de [esta] valorati6n [...],la contiencialinguisticade los hablantes andaluces se debate en la actualidad entre el complejo de inferioridad y la acepta- ti6n, con tierto orgullo, de la propia...

  18. -ESTUDIO Y TRATAMIENTO DEL DOLOR Los alumnos que hayan cursado los crditos obligatorios en el Mster Oficial que se

    E-print Network

    Rey Juan Carlos, Universidad

    procedentes de otros estudios oficiales de posgrado. En esos casos, la transferencia y reconocimiento de- ESTUDIO Y TRATAMIENTO DEL DOLOR Los alumnos que hayan cursado los créditos obligatorios en el Máster Oficial que se imparte en la actualidad, podrán solicitar su adaptación al nuevo plan de estudios

  19. Tratamiento Quirúrgico de los Meningiomas del Foramen Óptico, Técnicay Resultados de una Serie de 18 Pacientes

    PubMed Central

    Goldschmidt, Ezequiel; Ajler, Pablo; Campero, Álvaro; Landriel, Federico; Sposito, Maximiliano; Carrizo, Antonio

    2014-01-01

    Introducción: los meningiomas del foramen óptico producen un rápido deterioro de la función visual aún cuando su tamaño es pequeño, por eso su diagnóstico y manejo difiere del resto de los meningiomas clinoideos. El propósito de este estudio es presentar la técnica y los resultados de nuestro manejo quirúrgico de meningiomas foraminales (MF). Pacientes y Métodos: se llevó a cabo una revisión de las historias clínicas de 47 pacientes con meningiomas primarios intraorbitarios. Se realizaron 52 cirugías en los pacientes con MF. Se empleó una craneotomía fronto-orbitaria, seguida de una descompresión extradural del canal óptico, resección del componente intraorbitario y exploración intradural del nervio óptico. Resultados: de los 12 pacientes con MF que presentaban la visión conservada, la agudeza visual fue preservada en 7 casos, mejoró en 2, y empeoró en 3. En 18 pacientes, el principal síntoma fue exoftalmos y en 35 pacientes ceguera unilateral. Ocurrieron 6 recurrencias, 2 a 10 años después de la resección quirúrgica. Cinco de ellos fueron reoperados. Se indicó radioterapia después de la recurrencia en 3 pacientes. Conclusión: el manejo de los MF continúa siendo controvertido y frecuentemente se propone un tratamiento conservador. Basados en nuestros hallazgos de frecuente extensión intracraneal, proponemos realizar una resección total o subtotal del tumor, preservando el nervio óptico en pacientes con visión prequirúrgica conservada. PMID:25165616

  20. MAMA Software Features: Visual Examples of Quantification

    SciTech Connect

    Ruggiero, Christy E. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Porter, Reid B. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2014-05-20

    This document shows examples of the results from quantifying objects of certain sizes and types in the software. It is intended to give users a better feel for some of the quantification calculations, and, more importantly, to help users understand the challenges with using a small set of ‘shape’ quantification calculations for objects that can vary widely in shapes and features. We will add more examples to this in the coming year.

  1. Descriptive Morphology Terms For MAMA software

    SciTech Connect

    Ruggiero, Christy E. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Porter, Reid B. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2014-05-21

    The table on the following pages lists a set of morphology terms for describing materials. We have organized these terms by categories. Software uses are welcome to suggest other terms that are needed to accurately describe materials. This list is intended as a initial starting point to generating a consensus terminology list.

  2. Autoconcepto de mujeres con cáncer en mama

    Microsoft Academic Search

    Bañuelos-Barrera Patricia; Bañuelos-Barrera Yolanda; Esquivel-Rodríguez Martha; Moreno-Ávila Vanessa

    2007-01-01

    Abstract Abstract Abstract Abstract Introduction: Breast cancer is characterized for uncontrolled growing of cells; it is able to cause metastasis; it constitutes one of the first causes of mortality in the world for women. This disease affects the body image and self-concept which is defined by Roy as the notion of the individual by himself with emphasis on internal and

  3. Tratamiento del dolor agudo

    Microsoft Academic Search

    E. Blanco-Tarrío

    2010-01-01

    Acute pain is a physiological short-term response to an adverse stimulus associated with surgery, trauma or acute disease. A correct evaluation should be made, using simple, quick and useful pain intensity scales.The best interventional strategy should be to achieve a greater well-being with the least adverse effects. This should take into account the patient risk profile and the comorbidities.Acetaminophen (paracetamol)

  4. Tratamiento de Fibromialgia mediante Hipnosis

    Microsoft Academic Search

    F. Martínez Pintor; I. Pérez Hidalgo; J. Chamorro Álvarez; N. Martí Gasulla; A. Reig Gourlot

    2006-01-01

    Summary Nowadays the treatment of chronic pain syndrome such asfibromyalgia, only with the use of medication results obviously insufficient as we check in our every doy attendance. Considering the relevance ofthe emotional stress in the causes ofmany ofthese syndromes and also the con- cept of neuron plasticity, we decided to initiate a study inside a more general treatment which included

  5. Human milk oligosaccharides: every baby needs a sugar mama.

    PubMed

    Bode, Lars

    2012-09-01

    Human milk oligosaccharides (HMOs) are a family of structurally diverse unconjugated glycans that are highly abundant in and unique to human milk. Originally, HMOs were discovered as a prebiotic "bifidus factor" that serves as a metabolic substrate for desired bacteria and shapes an intestinal microbiota composition with health benefits for the breast-fed neonate. Today, HMOs are known to be more than just "food for bugs". An accumulating body of evidence suggests that HMOs are antiadhesive antimicrobials that serve as soluble decoy receptors, prevent pathogen attachment to infant mucosal surfaces and lower the risk for viral, bacterial and protozoan parasite infections. In addition, HMOs may modulate epithelial and immune cell responses, reduce excessive mucosal leukocyte infiltration and activation, lower the risk for necrotizing enterocolitis and provide the infant with sialic acid as a potentially essential nutrient for brain development and cognition. Most data, however, stem from in vitro, ex vivo or animal studies and occasionally from association studies in mother-infant cohorts. Powered, randomized and controlled intervention studies will be needed to confirm relevance for human neonates. The first part of this review introduces the pioneers in HMO research, outlines HMO structural diversity and describes what is known about HMO biosynthesis in the mother's mammary gland and their metabolism in the breast-fed infant. The second part highlights the postulated beneficial effects of HMO for the breast-fed neonate, compares HMOs with oligosaccharides in the milk of other mammals and in infant formula and summarizes the current roadblocks and future opportunities for HMO research. PMID:22513036

  6. Fibromatosis de mama: una lesión simuladora de cáncer

    Microsoft Academic Search

    Baltazar Alberto Soto-Dávalos; Juan Enrique Bargalló-Rocha; Artfy Bandera-Delgado; Oscar Zumaran-Cuéllar; Carlos Daniel Robles-Vidal

    2008-01-01

    Summary Background: Breast fibromatosis (BF) is a rare benign pathological entity. Its etiology is unknown, but it has been associated with surgical trauma and certain genetic disorders. Clinical cases: Case 1. The patient was a 17-year-old female with a 20 × 15 cm firm and fixed mass in the right breast. A core- needle biopsy was taken with a pathology

  7. Considerações sobre a prevenção do câncer de mama feminino

    Microsoft Academic Search

    Luiz Claudio Thuler

    Abstract Breast cancer control should place emphasis on preventing cancers or detecting cases in early stages. Prevention not only focuses on the risks associated with breast cancer but also on protective factors. Some factors that increase breast cancer risk, such as postmenopausal obesity, high-dose exposure to ionizing radiation, exposure to pesti- cides\\/organochlorines and tobacco use, are modifiable; other risk factors,

  8. Câncer de mama e sofrimento psicológico: aspectos relacionados ao feminino

    Microsoft Academic Search

    Lucia Cecilia da Silva

    2008-01-01

    The incidence of breast cancer in Brazil and all over the world has been rising and affected women at an earlier age. Treatment involves mastectomy, chemotherapy and radiotherapy whose side effects might compromise self-esteem, body image and feminine identity of the sick to various degrees. Moreover, in current society, cancer has acquired meanings associated with guilt, punishment, deterioration, pain and

  9. Factores pronósticos relacionados con la supervivencia del cáncer de mama

    Microsoft Academic Search

    Lourdes Flores-Luna; Eduardo Salazar-Martínez; Reyna Margarita Duarte-Torres; Gabriela Torres-Mejía; Patricia Alonso-Ruiz; Eduardo Lazcano-Ponce; Duarte-Torres RM

    2008-01-01

    Objective. To evaluate prognostic factors for breast cancer in Mexican women. Material and Methods. Four hundred and thirty two women with breast cancer, admitted from 1990 to 1999 to the General Hospital of Mexico, were included to evaluate their survival using the Kaplan-Meier technique and Cox proportional hazard method. Results. Overall 5-year survival was 58.9%. The shortest survival rate corresponds

  10. El Teatro Experimental La Mama en la dramaturgia nacional

    E-print Network

    Armando, Eddy

    1988-10-01

    ofrecemos a los participantes de este I Festival Iberoamerico de Teatro de Bogotá, un balance de nuestras actividades, gustoso fruto de nuestros trabajos: I-Más de 50 montajes, muchos de ellos de dramaturgia nacional, de autor o colectivos. 2-Múltiples..., plazas, colegios, universidades, sindicatos, barrios, empresas, poblaciones, resguardos indígenas, zonas campesinas, pero que también nos ha educado, transformado, señalándonos el camino de su historia y su problemática, reclamándonos una mejor...

  11. Pronóstico tras una agudización grave de la EPOC tratada con ventilación mecánica no invasiva

    Microsoft Academic Search

    Jose Echave-Sustaeta; Lorena Comeche Casanova; Ricardo García Luján; Javier Sayas Catalan; Agustin Gómez de la Cámara; Angel López Encuentra

    2010-01-01

    IntroductionPatients with chronic obstructive pulmonary disease (COPD) who survived an acute exacerbation with acute respiratory failure that required non-invasive mechanical ventilation (NIMV) are a group with a poor medium-term prognosis.

  12. Fisioterapia tras primera intervención de osteoplastia miniinvasiva en atrapamiento femoroacetabular en un hospital universitario

    Microsoft Academic Search

    C. L. Díaz Sánchez; M. C. Revert Gironés; F. J. Cabrera Santamaría; M. C. González Hernández; H. Álvarez Alcover

    2010-01-01

    The evolution of the surgical techniques in orthopaedics reverberates in the physical therapy treatments that must complete the good functional recovery of the patients. The femoroacetabular impingement (FAI) or impingement syndrome of the hip joint is treated by relatively conservative surgery and later rehabilitation. Herein, we present the first patient treated in our service. Furthermore, speaking of this case, we

  13. DISCAPACIDAD Y DESPLAZAMIENTO 41RMF35 En 2009, tras la violencia que se produjo

    E-print Network

    Escolano, Francisco

    acostumbrado a estos cambios. El año pasado sólo se aventuró una vez a salir de su manzana con su familia para reunirse con unos parientes. Pasa casi todo el tiempo en la tienda o en la manzana de diez tiendas. Para

  14. Congreso Internacional 1810-2010: 200 aos de Iberoamrica -1349 TICA Y ESTTICA TRAS EL DESAFO

    E-print Network

    Paris-Sud XI, Université de

    artístico y social, por la explosión que hizo volar el conjunto de viviendas protegidas Pritt-Igoe en 1972,seapoyabaenlosgrandesparadigmasosistemasdepensamiento políticos, sociales, científicos y religiosos. Desde ese momento de crisis deja de ser posible hablar de

  15. Utilidad de la escala INTERMACS para estratificar el pronóstico tras el trasplante cardiaco urgente

    Microsoft Academic Search

    Eduardo Barge-Caballero; María J. Paniagua-Martín; Raquel Marzoa-Rivas; Rosa Campo-Pérez; José Ángel Rodríguez-Fernández; Alberto Pérez-Pérez; Lourdes García-Bueno; Paula Blanco-Canosa; Zulaika Grille Cancela; Miguel Solla Buceta; Alberto Juffé-Stein; José M. Herrera-Noreña; José J. Cuenca-Castillo; Javier Muñiz; Alfonso Castro-Beiras; María G. Crespo-Leiro

    2011-01-01

    Introduction and objectivesOur aim was to assess the prognostic value of the INTERMACS (Interagency Registry for Mechanically Assisted Circulatory Support) scale in patients undergoing urgent heart transplantation (HT).

  16. Efectos adversos del tratamiento del cáncer oral

    Microsoft Academic Search

    F. J. Silvestre-Donat; A. Puente Sandoval

    2008-01-01

    SUMMARY In this article a revision of most frequent adverse effects of head and neck surgery, radiotherapy and chemotherapy is maid, because frequently general dentists deal with complications at their practises like mucositis, xerostomia, osteonecrosis, taste alterations and other pathologies which will cause disturbances to the patients, affecting their quality of live. The role of the dentist in the multidisciplinary

  17. Tratamientos psicológ icos eficaces para la agorafobia

    Microsoft Academic Search

    Arturo Bados López

    2001-01-01

    Efficacious psychological treatments for agoraphobia. In vivo exposure and cognitive-behavioral the - rapy have demonstrated their efficacy f or ag oraphobic anxiety and avoidance; however, the ef fects of cognitive-behavioral ther apy might be smaller if time g iven to in vivo exposure is r educed. Cogniti- ve-behavioral ther ap y is also a probably ef ficacious treatment f or

  18. Avances en el tratamiento de la amiloidosis

    Microsoft Academic Search

    Fernando Martinez-Valle; Mercedes Gironella Mesa; Roser Solans-Laqué

    Amyloidosis is a clinical disorder caused by extracellular deposition of proteins that are normally soluble as insoluble fibrils that damage different organs. More than 20 proteins can form amyloid deposits. All types of amyloid fibrils have a secondary structure with a ? folded shape that is characteristic and makes them to adopt a green birefringence after stained with Congo red

  19. "It’s like Big Mama’s house": Examining Extended Family Influences on the Dietary Behaviors of African American Children

    PubMed Central

    Brown, Natasha A.; Thornton, Rachel L. J.; Smith, Katherine Clegg; Surkan, Pamela J.; Levine, David M.

    2014-01-01

    The family environment plays an important role in influencing children’s dietary behaviors. Traditionally, African American extended family members play a key role in child socialization. We examine the role of extended families in how children are socialized to adopt dietary norms. We conducted in-depth, semi-structured interviews with 24 individuals across eight family units to elicit information regarding the influences of culture and families on children’s dietary behaviors. Findings suggest that families teach children to value activities that combine quality time and enjoying food together; adults are inconsistent in how they teach children to adopt desired dietary behaviors. This work has implications for improving family-based interventions for African American children through promoting healthful behaviors that are also respectful of family dietary traditions, improving communication between adults and children, and leveraging family members as attitudinal and behavioral referents. PMID:24564191

  20. GC-MS analysis of aroma of Medemia argun (mama-n-khanen or mama-n-xanin), an ancient Egyptian fruit palm.

    PubMed

    Hamed, Arafa I; Leonardi, Michele; Stochmal, Anna; Oleszek, Wieslaw; Pistelli, Luisa

    2012-05-01

    The fruits of the edible and medicinal Egyptian palm, Medemia argun, were collected from Aswan in Egypt and the essential oil (EO) from fruits and headspace (HS) of the seeds and fleshy mesocarps were analyzed by GC and GC-MS. Results obtained by GC-MS analysis indicated a high variability in the oil and in the headspace from seeds and mesocarps. Sesquiterpene derivatives were the main group of volatiles in the EO from fruits and in the HS from seeds (45.0 and 64.0%, respectively), while oxygenated hydrocarbon derivatives were the main constituents in the HS obtained from fleshy mesocarps (96.5%). The different chemical composition of the headspace obtained from the seeds and mesocarps of M. argun can be correlated with the different roles that the different constituents play in the prevention of dehydration of the fruits in the desert region from where the plant was collected. PMID:22799095

  1. Alzheimer Disease: "It's okay, Mama, if you want to go, it's okay".

    PubMed

    Hurley, Ann C; Volicer, Ladislav

    2002-11-13

    About 4 million people in the United States have Alzheimer disease (AD) and the number of incident cases is expected to more than double from 377,000 in 1995 to 959,000 in 2050. Patients, their families, and health care professionals struggle with a relentless and irreversible neurological syndrome that can last from 2 to 20 years. Alzheimer disease causes both cognitive and functional impairments that predispose the patient to behavioral symptoms, destroy intellectual capacity and personality, erase the ability to communicate one's wishes for care, and lead to life-threatening consequences. At the close of life, family members and clinicians face decisions regarding degrees of intensive medical care to be provided for treatment of the late-stage consequences of AD, including withdrawal of invasive interventions, initiation of hospice, and treatment of a range of progressive medical conditions. Physicians can assist patients with AD and their loved ones through the terminal phases of the illness by preparing them for the relentless progression of the disease and by supporting them through the intellectual and emotional conflicts accompanying the end of life. PMID:12425711

  2. MEASUREMENT OF PHTHALATE LEVELS IN HUMAN MILK IN THE US EPA MAMA STUDY

    EPA Science Inventory

    Phthalates are plasticizers used to impart flexibility in products including PVC, plastic toys, and medical devices. These products are widely used by the general population. Phthalates act as anti-androgens and in utero or perinatal exposure in laboratory animal models leads to ...

  3. Moratorium-achievement (MAMA) cycles in lifespan identity development: value orientations and reasoning system correlates.

    PubMed

    Stephen, J; Fraser, E; Marcia, J E

    1992-09-01

    Three important questions emerging in identity research are: Why do only some persons with Foreclosed identities move on to Identity Achievement? Why do some Identity Achievement persons move "back" to Foreclosure? How can life-span identity re-formulation be accounted for? This study proposes that individual's positions on two variables, "instrumental vs. experiential orientation" and formistic vs. dialectrical thinking, may be important in answering these questions. Among 60 university students, 23 males and 37 females, those in an identity status characterized by formation and maintenance of structure (Foreclosure) were instrumentally-oriented while those characterized by openness to change and revision (Moratorium) were experientially-oriented. Similarly, more Moratoriums than other statuses were high in dialectic thinking. These results are discussed in terms of their theoretical implications for life-span identity development. PMID:1447414

  4. A Method for Improving Intergenerational Encounters: The Case of Mama Bettie

    Microsoft Academic Search

    James R. Peacock; Jo Ann OQuin; Laura Pannell

    2009-01-01

    The purpose of this article is to describe a method for developing and improving intergenerational interactions or encounters. Older peoples' life experiences do not mirror the life experiences of younger cohorts today. As such, we propose a method for fostering intergenerational interactions and increasing bases for communication through exploring the life experiences of elders within the context of a larger

  5. Sexy Mamas? women, sexuality and reproduction in Australia in the 1940s

    Microsoft Academic Search

    Lisa Featherstone

    2005-01-01

    World War II is frequently read as a turning point in the construction of femininity. According to Marilyn Lake and others, during this period women were increasingly defined in terms of glamour and allure, and there was a new emphasis on youth, beauty and heterosexual attractiveness. The present article will complicate this view with an examination of sexuality after marriage.

  6. LA RELEVANCIA DE LA INTERVENCIÓN PSICOSOCIAL EN PACIENTES CON CÁNCER DE MAMA

    Microsoft Academic Search

    Marisol Pocino; Gissell Luna; Pablo Canelones; Andreína Mendoza; Gabriel Romero; Luis E. Palacios; Liliana Rivas; Marianela Castés

    2007-01-01

    Cancer diagnosis and disease progression induce high levels of stress that in some people go along with depression and anxiety. Objectives: To analyze the incidence of psychological alterations in breast cancer patients and possible modifications by a cognitive-behavioral treatment, that included relaxation and guided-imagery as well as stress management. Methods: Depression, anxiety and alexithymia were diagnosed by the use of

  7. Atención de enfermería a pacientes con cáncer de mama en cirugía mayor ambulatoria

    Microsoft Academic Search

    Carmen Cereijo; Ana Bazarra; Benigno Acea; Carmen González; Servando López; Berta Candía

    2005-01-01

    Currently, one of the aims of health planning is to improve the efficiency of the health system. As part of this aim, the implantation of ambulatory surgery programs is being consolidated, and new specialties and increasingly complex surgical techniques are being introduced.The implementation of an ambulatory surgery program for women with breast cancer required the nursing staff to adapt to

  8. Micrometástasis en el ganglio centinela y macrometástasis ganglionares axilares en el cáncer de mama

    Microsoft Academic Search

    J. M. Cordero García; M. Delgado Portela; A. M. García Vicente; J. P. Pilkington Woll; M. A. Palomar Muñoz; V. M. Poblete García; M. E. Bellón Guardia; R. Pardo García; L. Rabadán Ruiz; A. M. Soriano Castrejón

    2010-01-01

    AimThe study of the sentinel node has made it possible to obtain more comprehensive knowledge about the extent of axillary involvement in breast cancer. It has also decreased the surgical morbidity associated to the surgical examination of the axilla. The systematic use of immunohistochemical staining and molecular biology techniques improves the ability to detect the presence of micrometastasis or isolated

  9. La epidemia de cáncer de mama en México: ¿Consecuencia de la transición demográfica?

    Microsoft Academic Search

    OLGA LÓPEZ-RÍOS; EDUARDO CÉSAR LAZCANO-PONCE; VÍCTOR TOVAR-GUZMÁN; MAURICIO HERNÁNDEZ-AVILA

    1997-01-01

    Objective. Analyze the relation between reductions in fertility and the inverse en breast cancer mortality in the differents states of Mexico for the period 1979-1994. Materials and methods. Fertility rates and beast cancer mortality rates were utilized to analyze the proposed relationship in the states of the country. Principal component analysis and classification analysis were then used in the confirmatory

  10. Variáveis associadas ao câncer de mama em usuárias de unidades básicas de saúde

    Microsoft Academic Search

    Valéria Fernandes de Souza; Evandro Silva; Freire Coutinho

    An epidemiological survey in ten family health units in the municipality of Teresópolis, Rio de Janeiro State, Brazil, in 2003, investigated the distribution pattern of breast cancer risk fac- tors. 698 women 25 to 88 years of age were in- terviewed (112 rural and 586 urban). As for fac- tors associated with breast cancer, 36.1% were 50 years or older,

  11. Sistema Hipermídia com Interface Adaptativa em Câncer de Mama usando Redes Neurais Artificiais MLP e IAC

    Microsoft Academic Search

    Rosele Luchesi Paim; Fernando Mendes de Azevedo; Grácia Maria Koerich; Márcia dos Santos Malinverni; Rozany M. Dufloth; Daniella S. C. Vieira; Felipe Chaves Santos

    This article presents an interface adaptation methodology to hipermedia systems based on the methodology developed by Barbosa (1), where the site development with breast cancer contents is used to refine the students' knowledge of the healthy area of UFSC who receive in their classroom. While this system was been developed it was defined the adaptation will only occur in the

  12. Ansiedad anticipatoria asociada a las pruebas complementarias de screening de cáncer de mama

    Microsoft Academic Search

    Bonifacio Sandín; Paloma Chorot; Rosa M. Valiente; Lourdes Lostao; Miguel A. Santed

    2001-01-01

    Anticipatory anxiety in women r ecalled for further mammogram breast cancer screening. This inves- tigation examined anxiety, depressive mood, depression and somatic symptoms associated with a se - cond stage screening for breast cancer. Interviews were conducted with 1195 women 45-65 years old in two temporal conditions (pre- and post-mammogram). Participants included women attending for regular breast cancer screening who

  13. IMPACTO DEL LINFEDEMA EN LA CALIDAD DE VIDA DE LAS MUJERES CON CÁNCER DE MAMA

    Microsoft Academic Search

    Carmen Yélamos; Francisco Montesinos; Ana Eguino; Belén Fernández; Ana González; Marisa García; Ana Isabel Fernández

    2007-01-01

    This paper revises lymphoedema impact in a sample of women's quality of life, after breast cancer surgery, with or without lymphoedema diagnosis. 515 breast cancer patients cancer took part in this research, 253 of whom with lymphoedema diagnosis, 262 without. In a first stage, all women answered a structured ad hoc interview. In a second stage, 52 women with lymphoedema

  14. FUNDAMENTOS DE LA BIOPSIA DEL GANGLIO CENTINELA EN EL CÁNCER DE MAMA

    Microsoft Academic Search

    José María Román; Arancha Moreno; José Antonio Vidart

    Axillary lymph node dissection is the gold standard for detecting axillary disease in bre- ast cancer. Node status remains the most important prognostic factor, and is an impor- tant information to make decisions over fur- ther treatment. However, both the morbidity associated to this technique, and the fact that, due to mam- mografic screening, most of the cancer cases nowadays

  15. Detecção de Microcalcificações de Formas Especulares para Auxilio no Diagnóstico de Câncer de Mama

    Microsoft Academic Search

    Aledir Silveira Pereira; Kaori Yamaguchi

    The tumors in breasts, mainly in women they can represent to presence or not of malignidade (cancer). We develop and we implement in this phase from the research algorithms that analyze images mamographic and they detect microcalcifications that they possess borders you will speculate or rugous, as well as they detect group of nanocalcifications. According to research of Le Gall

  16. Supervivencia relativa en cáncer de mama después de la primera recidiva y factores pronóstico asociados

    Microsoft Academic Search

    Cristina Sarasqueta; Pablo Martínez-Camblor; Arantza Mendiola; Iñaki Martínez-Pueyo; Maria Jesús Michelena; Mikel Basterretxea; Javier Recio; Isabel Alvarez; Nerea Larrañaga

    2009-01-01

    Background and objectivesInformation regarding the incidence and prognosis of women who have suffered a recurrence of breast cancer is very variable. The aim of the present study was to determine the incidence of locoregional (LR) and distant recurrence and the survival and its determining factors after first recurrence.

  17. Jesus, Mama, and the constraints on salvific love in contemporary country music .

    PubMed

    Grossman, M L

    2002-01-01

    The discourse of contemporary country music creates a world permeated with religion and centered on the notion of salvific love. This form of salvation arises in the connection between people (or between people and God) and includes elements of sacrifice and transformation. Although highly conventional, country music must meet standards of 'authenticity' and 'relevance', which require the incorporation of contemporary American religious values (including self-love and self-actualization). An analysis of recent country music lyrics reveals the remarkable openness to new religious messages. However, the only acceptable messages are those that can be harmonized with the implicit Protestant Christian sensibility of the music. Salvific love, for this reason, is always heterosexual and at least compatible with a Christian message. While the music industry does its best to erase minority sexualities, the music itself is often surprisingly open to a queer interpretation. PMID:20681105

  18. El paradigma de la autogestión: producción social del hábitat en Argentina tras la crisis cívico-institucional de 2001

    Microsoft Academic Search

    Gustavo Diéguez; Guillermo Tella

    2008-01-01

    La reciente crisis argentina iniciada a fines de 2001 indujo a un estado particular de activación de novedosos modos de expresión de la sociedad. Si bien con el paso del tiempo ese clima de renovación de las prácticas sociales fue reabsorbido por la estructura institucional y la clase política que desató la crisis, se han registrado algunos avances en lo

  19. Tratamiento individualizado de la EPOC: una propuesta de cambio

    Microsoft Academic Search

    Marc Miravitlles

    2009-01-01

    Chronic obstructive pulmonary disease (COPD) is a highly prevalent but poorly defined disease and there is wide confusion regarding its treatment. The available knowledge should allow guidelines for specific treatment to be established according to each patient's clinical features. The present article describes a proposal for individually-tailored treatment. Long-acting bronchodilators, alone or in various combinations, would be the basis of

  20. La espiritualidad en el tratamiento del cáncer (PDQ®)

    Cancer.gov

    Resumen de información revisada por expertos acerca de la influencia que tiene la espiritualidad y la religión en las personas que tienen cáncer. Se discuten varios métodos sobre manejo e intervención.

  1. Tratamiento y prevención del síndrome de neurotoxicidad inducido por opioides

    Microsoft Academic Search

    C. CENTENO; E. BRUERA; Grey Nuns

    1999-01-01

    Close attention to patients treated with morphine or drugs derived from it can accelerate the diagnosis of the Opioid Induced Neurotoxicity Syndrome (OIN). It may allow the application of some therapeutic measu- res that provide hopeful results. Rotation of the type of opioid that had been used in combination with suitable hydration have been proved to be an efficient treatment

  2. Tratamiento quirúrgico en pacientes con hipertensión pulmonar tromboembólica crónica

    Microsoft Academic Search

    David Sánchez Lorente; Paolo Macchiarini

    2009-01-01

    Chronic thromboembolic pulmonary hypertension (CTEPH), which has a natural history with low long-term survival, is increasingly being diagnosed. Pulmonary endarterectomy (PE) is the treatment of choice, which can be curative. This technique consists of a true endarterectomy through a midline sternotomy with extracorporeal circulation and periods of hypothermic circulatory arrest. The following procedures should be performed before surgery: transesophageal echocardiogram,

  3. Tratamiento médico en pacientes con hipertensión pulmonar tromboembólica crónica

    Microsoft Academic Search

    Pilar Escribano Subias; María José Ruiz Cano; Ángela Flox

    2009-01-01

    Pulmonary thromboendarterectomy is the treatment of choice in patients with chronic thromboembolic pulmonary hypertension (CTEPH). However, specific medical treatment of pulmonary hypertension (PH) can be an alternative or play a complementary role to surgery. Thus, in patients unsuitable for surgery due to distal thrombotic obstruction, residual or persistent PH after surgery or very severe PH and a high-risk hemodynamic profile,

  4. Tratamiento de los síndromes periódicos asociados a la criopirina (CAPS)

    Microsoft Academic Search

    Santiago Jiménez Treviño; Eduardo Ramos Polo

    2011-01-01

    Non-steroidal anti-inflammatories, corticoids and antihistamines, as well as a great many other molecules, have classically been used to control the symptoms of cryopyrin-associated periodic syndromes (CAPS), with very few encouraging results. Knowledge of its genetic character, and its aetiopathogenesis associated with inflammasome and the production of interlekin-1 (IL-1) has led to the development of new therapeutic weapons that have not

  5. HEMORRAGIA DIGESTIVA ALTA AGUDA NO VARICOSA: TRATAMIENTO DE LA RECIDIVA

    Microsoft Academic Search

    Magna Adolfina Maidana; Sandra Elizabet Sesin; Marcos Ormella; Fernando David Boudot

    The upper gastrointestinal bleeding is the loss of blood into the light of digestive tract, caused by lesions, localized between the upper esophageal sphincter and the treiz angle. The recurrence, is defined as the presence of haematemesis or haemorrhagic signs of activity (hematico gastric aspirates and \\/ or melena) associated of hypovolaemia (PAS<100mmHg and \\/ or FC> 100 lat. \\/

  6. Tratamiento fisioterápico de la epicondilitis en un tenista joven

    Microsoft Academic Search

    M. Menayo Antúnez; R. Menayo Antúnez; J. P. Fuentes García; D. Sanz Rivas

    2005-01-01

    This case-study analyzed the physical therapy applied to a young tennis player with tennis elbow. It was placed in an interdisciplinary health team system for recovery based on the collaboration of physical therapist and trainer, permitting a rigorous and objective analysis of the different aspects considered as determinants for the injury, as well as the seriousness, the causes that provoked

  7. Tratamientos psicológ icos eficaces para el trastorno bipolar

    Microsoft Academic Search

    Carmen Lorenzo

    Efficacious psychological treatments for bipolar disorder. The bipolar disorder is a chronic dysfunc- tion and a illness condition f or many people. Their treatment has been classically pharmacological (lit - hium), although in the last y ears it has been demonstrated that its combina tion with different psycho- logical treatments allows a bigg er impr ovement in these patients. The

  8. Citología con atipias en células glandulares. Evaluación, tratamiento y resultados

    Microsoft Academic Search

    Daniel Andía Ortiz; Enrique Izaguirre Gondra; Borja Rivero Torrejón; Mikel Goitia Ibarra

    2006-01-01

    ObjectiveTo study the frequency of a cytological result of atypical glandular cells of unknown significance\\/atypical glandular cells, not otherwise specified (AGUS\\/GAC-NOS) in the pap smear and the final diagnosis in patients with this result.

  9. El grano y la criba de los tratamientos psicológ icos

    Microsoft Academic Search

    Marino Pérez

    Se presentan las conclusiones de revisar la eficacia (así como la efectividad) terapéutica par a los ca- torce tr astornos psicológ icos siguientes: Esquizofrenia, Drogadicción, Anor exia y Bulimia, Trastornos de Personalidad, Hipocondría, Trastorno Obsesivo Compulsivo, Disfunciones Se xuales, Ansiedad Ge- neralizada, Fobias Específicas, Agorafobia, Trastorno de Pánico, Trastorno por Estrés P ost-traumáti- co, Depresión unipolar y De presión bipolar

  10. Como Lo Hago Yo: Tratamiento Quirurgico Del Mielomeningocele

    PubMed Central

    Portillo, Santiago

    2014-01-01

    En Argentina hay plan de fortificación con ácido fólico. Diagnostico prenatal no siempre es correcto. Cierre según técnica. Cerramos músculo. No favorecemos corpectomía temprana en casos de cifosis. Suturamos la plaqueta. Cerramos el plano muscular. Hidrocefalia: Válvula de derivación, generalmente dentro de los dos primeros meses. Ventriculostomía no está indicada. Chiari II. Laminectomia cervical alta. Siringomielia: Derivación desde la cavidad al peritoneo. PMID:24791219

  11. Eight new genomes and synthetic controls increase the accessibility of rapid melt-MAMA SNP typing of Coxiella burnetii.

    PubMed

    Karlsson, Edvin; Macellaro, Anna; Byström, Mona; Forsman, Mats; Frangoulidis, Dimitrios; Janse, Ingmar; Larsson, Pär; Lindgren, Petter; Ohrman, Caroline; van Rotterdam, Bart; Sjödin, Andreas; Myrtennäs, Kerstin

    2014-01-01

    The case rate of Q fever in Europe has increased dramatically in recent years, mainly because of an epidemic in the Netherlands in 2009. Consequently, there is a need for more extensive genetic characterization of the disease agent Coxiella burnetii in order to better understand the epidemiology and spread of this disease. Genome reference data are essential for this purpose, but only thirteen genome sequences are currently available. Current methods for typing C. burnetii are criticized for having problems in comparing results across laboratories, require the use of genomic control DNA, and/or rely on markers in highly variable regions. We developed in this work a method for single nucleotide polymorphism (SNP) typing of C. burnetii isolates and tissue samples based on new assays targeting ten phylogenetically stable synonymous canonical SNPs (canSNPs). These canSNPs represent previously known phylogenetic branches and were here identified from sequence comparisons of twenty-one C. burnetii genomes, eight of which were sequenced in this work. Importantly, synthetic control templates were developed, to make the method useful to laboratories lacking genomic control DNA. An analysis of twenty-one C. burnetii genomes confirmed that the species exhibits high sequence identity. Most of its SNPs (7,493/7,559 shared by >1 genome) follow a clonal inheritance pattern and are therefore stable phylogenetic typing markers. The assays were validated using twenty-six genetically diverse C. burnetii isolates and three tissue samples from small ruminants infected during the epidemic in the Netherlands. Each sample was assigned to a clade. Synthetic controls (vector and PCR amplified) gave identical results compared to the corresponding genomic controls and are viable alternatives to genomic DNA. The results from the described method indicate that it could be useful for cheap and rapid disease source tracking at non-specialized laboratories, which requires accurate genotyping, assay accessibility and inter-laboratory comparisons. PMID:24465554

  12. A common structure for concepts of individuals, stuffs, and real kinds: More Mama, more milk, and more mouse

    Microsoft Academic Search

    Ruth Garrett Millikan

    1998-01-01

    Concepts are highly theoretical entities. One cannot study them empirically without committing oneself to substantial preliminary assumptions. Among the competing theories of concepts and categorization developed by psychologists in the last thirty years, the implicit theoretical assumption that what falls under a concept is determined by description (\\

  13. Recovering from "Yo Mama Is so Stupid": (En)gendering a Critical Paradigm on Black Feminist Theory and Pedagogy

    ERIC Educational Resources Information Center

    Brock, Rochelle

    2011-01-01

    This article offers an analysis of the dozens using Black feminist theory. The dozens are a ritualized verbal game of insults that historically have used sexual offenses against Black women as the vehicle for insults. Rather than simply viewing the dozens as a cultural phenomenon, the article draws a connection between its occurrence in West…

  14. AVALIAÇÃO DA QUALIDADE DE VIDA EM MULHERES COM CANCRO DA MAMA: UM ESTUDO EXPLORATÓRIO COM 60 MULHERES PORTUGUESAS

    Microsoft Academic Search

    Virgínia Rebelo; Luísa Rolim; Eduardo Carqueja; Silva Ferreira; Unidade da Dor

    2007-01-01

    Abstract: The aim of this study was to evaluate the quality of life in 60 Portuguese women diagnosed with breast cancer, who were already submitted to surgery (mastectomy or tumorectomy), and are presently undergoing chemotherapy treatment at Hospital de São João (Porto, Portugal). The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30) and Supplementary

  15. The Mamas and the Papas: The Invisible Diversity of Families with Same-Sex Parents in the United States

    ERIC Educational Resources Information Center

    Rimalower, Lucy; Caty, Caren

    2009-01-01

    This literature review is intended for administrators, educators, and counselors to generate discussion and awareness of the issues facing families with same-sex parents in the United States, a demographic that is rapidly growing and needing service and attention from its communities. To provide educators with background into how these families…

  16. A participação das mulheres com câncer de mama na escolha do tratamento: um direito a ser conquistado

    Microsoft Academic Search

    Sandra Lucia Arantes; Marli Villela Mamede

    2003-01-01

    The purpose of this study was to identify how women with breast cancer perceive themselves as subjects in the process of making decisions on their own treatment. Two objectives were pursued: (a) to identify social and political determinants that, by affecting the socialization process of these women, might have influenced them in adopting a style of participation, and (b) to

  17. Recruitment and Retention of Pregnant Women for a Behavioral Intervention: Lessons from the Maternal Adiposity, Metabolism, and Stress (MAMAS) Study

    PubMed Central

    Laraia, Barbara A.; Adler, Nancy; Vieten, Cassandra; Thomas, Melanie; Epel, Elissa

    2013-01-01

    Introduction Recruiting participants for research studies can be challenging. Many studies fall short of their target or must prolong recruitment to reach it. We examined recruitment and retention strategies and report lessons learned in a behavioral intervention developmental trial to encourage healthy pregnancy weight gain and stress reduction in low-income overweight pregnant women. Methods In the San Francisco Bay area from February 2010 through March 2011, we used direct and indirect strategies to recruit English-speaking overweight and obese pregnant women who were aged 18 to 45, were in the early stages of pregnancy, and who had an annual household income less than 500% of the federal poverty guidelines. Eligible women who consented participated in focus groups or an 8-week behavioral intervention. We identified successful recruiting strategies and sites and calculated the percentage of women who were enrolled and retained. Results Of 127 women screened for focus group participation, 69 were eligible and enrolled. A total of 57 women participated in 9 focus groups and 3 women completed individual interviews for a completion rate of 87%. During recruitment for the intervention, we made contact with 204 women; 135 were screened, 33% were eligible, and 69.1% of eligible women enrolled. At 1 month postpartum, 82.6% of eligible women completed an assessment. Recruiting at hospital-based prenatal clinics was the highest-yielding strategy. Conclusion The narrow window of eligibility for enrolling early stage pregnant women in a group intervention presents obstacles. In-person recruitment was the most successful strategy; establishing close relationships with providers, clinic staff, social service providers, and study participants was essential to successful recruitment and retention. PMID:23469765

  18. And My Mama Said...: The (Relative) Parental Influence on Fear of Crime among Adolescent Girls and Boys

    ERIC Educational Resources Information Center

    De Groof, Saskia

    2008-01-01

    Many studies have been conducted to examine the predictors of fear of crime among adults, but feelings of insecurity among children and adolescents have been practically ignored. The aim of this study is to search for relevant determinants of fear of crime in a representative sample of 1,212 Flemish (Belgian) adolescents, age 14 to 18, and one of…

  19. Evaluación de la calidad del procedimiento de biopsia selectiva de ganglio centinela en pacientes con cáncer de mama

    Microsoft Academic Search

    M. Pajares; J. M. Freire; P. Moreno; A. Utor; A. Tocino; E. Alonso

    2010-01-01

    The Sentinel Lymph Node Biopsy (SLNB) has been demonstrated to be a safe alternative to axillary lymph node dissection in breast cancer staging. The multidisciplinary team must do it with rigor and demonstrate that they have fulfilled some essential criteria.

  20. Optimización de la biopsia selectiva de ganglio centinela en el cáncer de mama mediante palpación axilar intraoperatoria

    Microsoft Academic Search

    J. Serrano Vicente; J. R. Infante de la Torre; M. L. Domínguez Grande; L. García Bernardo; C. Durán Barquero; J. I. Rayo Madrid; R. Sánchez Sánchez; M. I. Correa Antúnez; J. L. Amaya Lozano; A. F. Conde Martín

    2010-01-01

    IntroductionSentinel node biopsy (SNB) by radioisotopes is a widely accepted and reliable surgical method for staging breast cancer in patients with unknown positive axillary lymph nodes involvement. The main limitation of this method is due to the appearance of false negatives that may be caused by tumor lymph node blockage of the sentinel lymph node and uptake in the neighboring

  1. Análisis de las tendencias de mortalidad por cáncer de mama en Colombia y Bogotá 1981-2000

    Microsoft Academic Search

    Gustavo Hernández; Santiago Herrán; Luis Fernando Cantor

    Abstract Introduction: In Colombia, breast cancer mortality has increased. Paradoxically, Bogota with the highest rates showed a decreasing trend. In this study we examined age, cohort and period effects over breast cancer mortality trends in Bogotá and Colombia as a whole (excluding Bogota) between,1981 and 2000.

  2. Mama just won’t accept this”: Adult Perspectives on Engaging Depressed African American Teens in Clinical Research and Treatment

    Microsoft Academic Search

    Alfiee M. Breland-Noble; Carl C. Bell; Antoinette Burriss

    This manuscript focuses on qualitative data collected for AAKOMA Project, a 2-phase treatment engagement intervention trial\\u000a for depressed African American adolescents and families. Data are presented from our phase I study of adult perspectives on\\u000a African American adolescent depression, depression treatment, and research engagement. The research team conducted four focus\\u000a groups (N = 24) and generated major themes from the data including

  3. Independencia para actividades de la vida diaria en ancianos previamente autónomos intervenidos por fractura de cadera secundaria a una caída tras 6 meses de evolución

    Microsoft Academic Search

    Eduardo Candel-Parra; María Pilar Córcoles-Jiménez; María Ángeles del Egidofernández; Ascensión Villada-Munera; María Delirio Jiménez-Sánchez; Mónica Moreno-Moreno; Miriam Carrión-González; Ángeles Denia-Cortés

    2008-01-01

    ObjectiveTo measure recovery of independence in activities of daily living (ADL) 6 months after surgery in elderly patients (previously independent and without cognitive impairment) with hip fracture caused by a fall.

  4. En un solemne acto que se celebr el pasado 15 de marzo, Eu-genio Tras Sagnier y Jos Saramago fueron investidos como doc-

    E-print Network

    Autonoma de Madrid, Universidad

    como "una de las figuras más destacadas de la filosofía de nuestro tiempo. La aparición de sus primeros Albaladejo realizó un extenso viaje por la vida y la obra del escritor, destacando su vinculación con la

  5. Uruguay: La ANEP tras un proceso de reforma y dos administraciones (1995-2004): Estado de situación, perspectivas y recomendaciones de política

    Microsoft Academic Search

    Darwin Caraballo; Gustavo de Armas; David Glejberman

    2005-01-01

    A partir de 1995 Uruguay inició un proceso de reforma del sistema educativo con el propósito de mejorar la calidad de la educación, procurar la equidad social, reivindicar y profesionalizar la función docente y modernizar el sistema de gestión institucional. En el presente documento se pretende identificar y precisar los problemas que aún persisten luego de nueve años de iniciada

  6. Nutr Hosp. 2012;27(6):1973-1980 ISSN 0212-1611 CODEN NUHOEQ

    E-print Network

    Floeter, Sergio Ricardo

    DIAGNÓSTICO RECIENTE DE CÁNCER DE MAMA: UNA COMPARACIÓN CON LAS RECOMENDACIONES DEL SEGUNDO INFORME DE LA WCRF de vida de las mujeres con diagnóstico reciente de cáncer de mama según el recomendaciones del.3305/nh.2012.27.6.6006 Palabras clave: Cáncer de mama. Prevención y control. Estilo de vida. Alimentación

  7. EVALUACIÓN E INTERVENCIÓN PSICOLÓGICA EN UN CASO DE TRASTORNO ADAPTATIVO MIXTO CON ANSIEDAD Y ESTADO DE ÁNIMO DEPRESIVO EN UNA MUJER CON RECIDIVA POR CÁNCER DE MAMA

    Microsoft Academic Search

    Paula Andrea Barraza; Facultad de Psicología

    2004-01-01

    Adjustment Disorder is at present the most frequently diagnosed psychopathology among cancer patients. In this article a case report of an adjustment disorder with mixed mood, anxiety and depressed mood, in a woman with breast cancer recurrence, is presented. A brief psychological intervention, in the crisis intervention model, cognitive - behavioural oriented is proposed. Problems expressed at physiological, motor and

  8. Reunión de Consenso sobre la biopsia selectiva del ganglio centinela en el cáncer de mama. Sociedad Española de Senología y Patología Mamaria

    Microsoft Academic Search

    A. Piñero; J. Giménez; B. Merck; C. Vázquez

    2007-01-01

    Selective biopsy of the sentinel node is a useful diagnostic technique in the management of breast cancer that has been introduced into the clinical practice and is widely used and accepted. Based on its results, adequate staging can be made with less associated morbidity. However, at present, there are many methodological variations in how it is done that are pending

  9. «Esa corporeidad mortal y rosa»: análisis del tiempo libre de enfermedad del cáncer de mama en Gipuzkoa en presencia de riesgos competitivos

    Microsoft Academic Search

    Pablo Martínez-Camblor; Nerea Larrañaga; Cristina Sarasqueta; María José Mitxelena; Mikel Basterretxea

    2009-01-01

    ObjectiveTo analyze time of disease-free survival and relative survival in women diagnosed with breast cancer in the province of Gipuzkoa within the context of competing risks by assessing differences between the direct use of the Kaplan-Meier estimator and the multiple decrement method on the one hand, and relative survival on the other.

  10. ESTUDIO CINETICO DE LA DEGRADACION DE LA ACTIVIDAD ANTIOXIDANTE HIDROSOLUBLE DE JUGOS CITRICOS POR TRATAMIENTO TERMICO

    Microsoft Academic Search

    Belén ACEVEDO; Mabel MONTIEL; Jorge AVANZA

    In this work we have studied the degradation of Antioxidant Activities by thermic treat- ment at 70, 80 y 90ºC in juices of varios citrus: orange (Citrus sinensis), mandarins (Citrus reticu- lata), lemon (Citrus limon), pomelo (Citrus paradisi) y lime Rangpur (Citrus limonia Osbeck). Antioxidant Activities were measured using the DPPH method. Antioxidant Activities degradation follows a zero-order reaction.

  11. Várices por insuficiencia de la vena perforante poplítea. Nuestra experiencia en el diagnóstico y tratamiento quirúrgico

    Microsoft Academic Search

    Jorge A. Pozzi

    Introduction: Until recently, popliteal perforator vein insufficiency was not considered as a source of varicose veins. The study of its diagnosis and treatment must be considered by the vascular surgeon to avoid varicose recurrences at the popliteal region. Objectives: To show the results of the diagnostic and therapeutic measures in limbs with popliteal perforator vein insufficiency and its complications. Patients

  12. Sigla: MAT-224. Cronograma de tratamiento de los contenidos Profesora: I Markina.

    E-print Network

    Markina, Irina

    .00. SEMANA CONTENIDOS Julio 21 ­ Julio25 Espacios topológicos y espacios medibles. Funciones medibles, composición funciones continuas y medibles. Álgebra de Borel. Limites superiores y inferiores. Funciones simples, aproximación de funciones medibles por funciones simples. Julio 28 ­ Agosto 1 Medidas positivas

  13. Radioterapia preoperatoria frente a cirugía como tratamiento en el carcinoma de recto

    Microsoft Academic Search

    María del Carmen Fernández Fernández; Luis Errázquin de Sáenz Tejada; María Dolores Jiménez Gamero; Carmen Cordero Fernández

    2001-01-01

    Resumen  El propósito fue realizar un estudio retrospectivo de 133 pacientes afectados por un carcinoma rectal en el cual se ha comparado\\u000a la supervivencia, la supervivencia libre de recurrencia local y las complicaciones de 61 pacientes tratados con radioterapia\\u000a preoperatorio con 72 pacientes tratados solamente con cirugía.\\u000a \\u000a En cuanto al material y los métodos, se realizó un estudio retrospectivo de 61

  14. Evaluación de un componente de inducción al tratamiento con adolescentes usuarios de alcohol del Distrito Federal

    Microsoft Academic Search

    Martha Leticia; Salazar Garza; Kalina Isela Martínez Martínez; Vania Barrientos Casarrubias

    2009-01-01

    SUMMARY There are two main problems reported in the intervention programs addressing teenage substance users: 1) limited admission to treatment, 2) high drop out rates. Institutions in other countries working with teenage substance users report a dropout rate between 50 and 70% after the first session at early treatment stages. In Mexico, a study on dropout rates in a brief

  15. Láser infrarrojo frente a acupuntura en el tratamiento del espolón calcáneo

    Microsoft Academic Search

    A. Orellana Molina; A. Hernández Díaz; P. J. Larrea Cox; S. Fernández Yanes; B. M. González Méndez

    2010-01-01

    IntroductionPhysical Medicine and Rehabilitation and Traditional and Natural Medicine are medical specialties that develop measures for the promotion of health, prevention, diagnosis and treatment, using physiotherapy and natural agents, along with acupuncture and therapeutic laser. The heel spur is an osteophyte that grows in the front part of the plantar tuberosity of the heel bone secondary to inflammatory processes of

  16. Tratamiento hormonal de reasignación de sexo en España: nuestra experiencia en 236 casos

    Microsoft Academic Search

    Antonio Becerra Fernández; María Jesús Lucio Pérez; José Luis Llopis Agelan

    2007-01-01

    IntroductionIn recent decades, demand for gender reassignment therapy (psychological, hormonal and surgical) has significantly increased. In Spain, this type of therapy has not generally been provided in public hospitals. Consequently, endocrinologists and other health professionals have insufficient experience of this treatment and transsexuals have to resort to self therapy or to private hospitals.

  17. Tratamiento de Afecciones Músculo-Esqueléticas con Ondas de Choque Extracorpóreas

    Microsoft Academic Search

    Juan Luis

    Summary Extracorporeal shock waves are pressure waves used to treat certain musculoskeletal conditions. Focused wave therapy, the same that is used in lithotripsy, but acting through a different mechanism, is used to treat pseudoar- thritis and delayed consolidation, avascular necrosis of large joints, osteochondritis dissecans, calcific tendoni - tis and enthesopathies. We study its use in myocardial infarction. Results are

  18. RESULTADOS DEL TRATAMIENTO QUIRÚRGICO DE LOS NEU ROMAS INTERDIGITALES MEDIANTE TÉCNICAS MÍNIMAMENTE INVASIVAS

    Microsoft Academic Search

    Señarís J; Baamonde C; Aizpurúa J; Prego A; Arriaza R

    SUMMARY In the last years diverse minimally invasive techni- ques have been developed for the treatment of foot pathologies. In case of the interdigital neuromas, it has proposed to realize percutaneal osteotomies of t the adjacent metatarsal neck to the injury, as well as the percutaneal liberation of the intermetatarsal ligament of the sympathetic space, with the aim of decompress

  19. Gliomas del adulto: acercamiento al diagnóstico y tratamiento Gliomas in adults: diagnostic and therapeutical approach

    Microsoft Academic Search

    Germán Alonso; Reyes Botero

    SUMMARY Gliomas are the most common primary malignancies of central nervous system. Progress in neuroradiology with use of magnetic resonance imaging allows establishing diagnosis in earlier when an opportune treatment can be perfformed. Even though prognosis is poor for this group of patients, evidence has showed that treatments with surgery, radiotherapy and chemotherapy have a significant impact in quality of

  20. Tratamiento farmacológico de la mujer embarazada: fármacos contraindicados durante la gestación

    Microsoft Academic Search

    E. Rodríguez-Pinilla; M. L. Martínez-Frías

    As primary care doctors treat pregnant women and those of fertile age, they must decide which treatments they should follow. Therefore, they have to confront the difficult situation of assessing the risks that different alternative treatments may have on embryo\\/foetal development. An assessment that is not straightforward as established general guidelines may not be applicable. For example, one drug may

  1. Cmo expresar sus deseos sobre su cuidado y tratamiento 450 Brookline Ave.

    E-print Network

    Liu, Xiaole Shirley

    podría obtener. Se necesita la toma seria de decisiones médicas al considerar las numerosas opciones.dana-farber.org Decisiones para cuidados de salud: planificación por adelantado Usted tiene derecho a tomar las decisiones decisiones médicas por sí mismo. En Massachusetts, la persona que usted elige se denomina apoderado de

  2. EL USO DE LA VISUALIZACIÓN EN EL TRATAMIENTO PSICOLÓGICO DE ENFERMOS DE CÁNCER

    Microsoft Academic Search

    María Valiente

    2006-01-01

    The article is attempting to offer a histo- rical vision on the evolution and beginning of technology of visualization. He gave a brief review on his different uses and his clinical application up to the present about patients with cancer. Finally, included in the article is the called visualization of the Simonton Therapy, refe- rring to the controversy provoke on

  3. La hipnosis como adjunto en el tratamiento del hábito de fumar. Estudio de caso

    Microsoft Academic Search

    María Elena; Mendoza Figueroa

    2000-01-01

    Se presenta el caso de una paciente de 33 años con dependencia a la nicotina que lle vaba 9 años fu- mando una media de 35 cigarrillos diarios. Intentó dejarlo hace 3 años pero tuvo una recaída a los seis meses por problemas de ansiedad y continuó con su adicción. El tr atamiento tuvo como objetivo que la paciente dejara

  4. SIMULACIÓN MATEMÁTICA DE UN DIGESTOR ANAEROBIO TIPO TANQUE AGITADO PARA EL TRATAMIENTO DE VERTIDOS RESIDUALES

    Microsoft Academic Search

    Jorge DEL REAL OLVERA; Francisco PRIETO GARCÍA; Eva María; SANTOS LÓPEZ

    2009-01-01

    In the last years, mathematical modeling has been used to try to represent the chemi- cal changes that occur in the environment. Traditionally the models are based on the mass balance and the kinetic chemistry of the bioprocesses. In this study the equations obtained for a biological isothermal reactor type shaken tank are applied and simulated by using adimensional linear

  5. La depresión con inicio temprano: prevalencia, curso natural y latencia para buscar tratamiento

    Microsoft Academic Search

    Corina Benjet; Guilherme Borges; Ma Elena Medina-Mora; Clara Fleiz-Bautista; Joaquín Zambrano-Ruiz

    2004-01-01

    Objective. To estimate the prevalence of early onset de- pression in the Mexican population and compare its natural history, comorbidity and treatment latency between early onset and adult onset depression. Material and Meth- ods. The National Survey of Psychiatric Epidemiology (ENEP) is representative of the Mexican urban population aged 18 to 65. The diagnostic instrument is the Composite Interna- tional

  6. AVANCES EN EL TRATAMIENTO COGNITIVO-CONDUCTUAL DEL TRASTORNO DE ESTRÉS POSTRAUMÁTICO

    Microsoft Academic Search

    Enrique Echeburúa; Paz de Corral

    This paper deals with a review of the literature on cognitive-behavioral treatment for post-traumatic stress disorder. Addresses 2 issues: different types of victims (rape victims as well as victims of natural disasters and motor vehicle ac- cidents) and different sets of treatments (exposure based procedures, eye movement desensitization and reprocessing, and anxiety management tech- niques). The relevance of this review

  7. Situación de la braquiterapia en España. Análisis de complejidad y tiempos de preparación y tratamiento

    Microsoft Academic Search

    José López Torrecilla; Ernesto Bataller Alonso

    2001-01-01

    Resumen  Se ha analizado la situación de la braquiterapia en los hospitales españoles y valorado la complejidad y el tiempo que se\\u000a emplea en la realización de las aplicaciones.\\u000a \\u000a En mayo de 1999 se envió una encuesta, dividida en 2 partes a 71 servicios de Oncología Radioterápica. La primera tenía por\\u000a objeto conocer la carga asistencial del servicio y la segunda

  8. Paralelizacion y Optimizacion a bajo nivel de algoritmos de tratamiento de imagenes

    E-print Network

    Granada, Universidad de

    im´agenes tienen una alta demanda de CPU, lo cual se traduce en un elevado consumo de tiempo de tiempo de ejecuci´on del soft- ware mediante una gran cantidad de t´ecnicas difer- entes: aumento de la procesamiento de datos en tiempo real. Centr´andonos en las t´ecnicas utilizadas en este art´iculo, cabe

  9. TRATAMIENTO DE EFLUENTES DE DESTILERÍA EN UN FILTRO ANAEROBIO DE FLUJO ASCENDENTE

    Microsoft Academic Search

    Alejandro RIVERA; Jorge S. GONZÁLEZ; Reinaldo CASTRO; Barbarita GUERRERO; Gertrudis NIEVES

    The possibility of using an upflow anaerobic filter, packed with Raschig rings, for the treatment of distillery effluents was demonstrated. Mantaining a hydraulic retention time of 48 hours, organic loads varying from 0.20 to 10.52 kg COD\\/m 3 day were applied. COD removal efficiencies over 65 % were achieved with only one pass through the reactor, for organic loads below

  10. TÉCNICAS FISIOTERÁPICAS Y OSTEOPÁTICAS EN EL TRATAMIENTO DE LA CEFALEA TENSIONAL

    Microsoft Academic Search

    ELISA ROMERO OLUCHA; ROBERT ROIG REQUENA

    The tension-type headache is a problem that affects a lot of people, but nowadays it hasn't yet been determined with certainty the etiology of the problem, and therefore the various proposed treatments are more or less effective, although neither the totally eradicated.

  11. Ensayo no aleatorizado del tratamiento con acupuntura de la cefalea resistente a terapias convencionales

    Microsoft Academic Search

    E. Collazo

    2010-01-01

    ObjectivesTo evaluate the overall effectiveness of acupuncture as a complementary therapy in relieving chronic pain in paired groups (before-after) of patients with headache refractory to conventional therapies in a real life clinical setting. To determine the extent to which analgesic consumption is reduced in these patients after an acupuncture cycle. To determine the adverse reactions due to acupuncture.

  12. Un caso de cefalea post traumática: consideraciones sobre clasificación, fisiopatología y tratamiento

    Microsoft Academic Search

    M. G. Meli

    2010-01-01

    Case report of a 35 year old woman with a post traumatic headache (PTH). Onset of the pain three years earlier, after falling on the ground, which required resuscitation. She had to be on mechanical ventilation for 11 days and suffered several contusions on the right frontal-temporal area of the skull. On discharge, she complained of a continuous bilateral tension

  13. La espiritualidad en el tratamiento del cáncer–para profesionales de salud (PDQ®)

    Cancer.gov

    Resumen de información revisada por expertos acerca de la influencia que tiene la espiritualidad y la religión en las personas que tienen cáncer. Se discuten varios métodos sobre manejo e intervención.

  14. UUUNNNIIIVVVEEERRRSSSIIIDDDAAADDD CCCOOOMMMPPPLLLUUUTTTEEENNNSSSEEE DDDEEE MMMAAADDDRRRIIIDDD 222333,,, 222444 YYY 222555 dddeee MMMAAARRRZZZOOO dddeee 222000111555

    E-print Network

    Escolano, Francisco

    222333,,, 222444 YYY 222555 dddeee MMMAAARRRZZZOOO dddeee 222000111555 Tras comprobar el éxito cosechado deberán JJJOOORRRNNNAAADDDAAASSS DDDEEE DDDOOOCCCTTTOOORRRAAANNNDDDOOOSSS EEENNN LLLEEENNNGGGUUUAAA YYY

  15. Dietary flaxseed-trastuzumab interactive effects on the growth of HER2-overexpressing human breast tumors (BT-474).

    PubMed

    Mason, Julie K; Fu, Ming-Hua; Chen, Jianmin; Yu, Zhe; Thompson, Lilian U

    2013-01-01

    Flaxseed (FS) reduces breast tumorigenesis and human epidermal growth factor receptor 2 (HER2) expression in postmenopausal patients and animal models. The primary treatment for HER2-overexpressing tumors is trastuzumab (TRAS). FS oil enhances TRAS effectiveness in athymic mice but the FS effect is unknown and was therefore determined. Athymic mice with established BT-474 tumors were fed the basal diet (control), or 10% FS diet, with or without TRAS (2.5mg/kg) treatment for 5 wk. After 2 wk, TRAS and FS reduced tumor size with a trend for an FS × TRAS interaction; however, after 5 wk, only TRAS reduced tumor size and increased tumor apoptosis. FS did not further improve TRAS effect but increased overall survival. TRAS reduced signaling biomarkers [phosphorylated HER2 and mitogen-activated protein kinase (MAPK) proteins; Akt1, Akt2, MAPK, and estrogen receptor-? mRNA], FS reduced phosphorylated-Akt1 protein, and FS × TRAS interactions were seen for HER2 mRNA and phosphorylated-Akt1 protein. FS, with and without TRAS, increased tumor n-3 PUFA levels and serum lignans indicating potential roles in the observed effect. In conclusion, TRAS reduces tumor growth by influencing HER2 signaling. Dietary FS has minimal tumor-reducing effect, does not interfere with TRAS action, but improves overall survival in athymic mice. PMID:23530645

  16. Aerotransportables viables en el área de tratamiento y disposición final de residuos sólidos municipales de Mérida, Yucatán

    Microsoft Academic Search

    Julia Pacheco A

    Solid waste managing and disposal systems can contribute to the dispersion of the microorganisms. The presence and dispersion of bioaerosols from these sites is considered as a potential human health risk for site-workers and surrounding communities. The aim of this work was to quantify and determine the dispersion of bioaerosols, in the area of recycling, composting and disposal of municipal

  17. Prcticas jurdicas entre la asistencia/tratamiento y el castigo/punicin: ideas penales en el Brasil republicano1

    E-print Network

    Boyer, Edmond

    Brasil republicano1 Rivail Carvalho Rolim ­ UEM-CAPES-Brasil2 Resumen A principios de la década de 1940, Brasil cambió su ordenamiento jurídico- penal, introduciendo nuevos principios y postulados para la. ______________________________________________________________________ Palabras claves: cultura jurídico-penal; Brasil Republicano; derechos de los presos

  18. Variabilidad en la realización de la espirometría y sus consecuencias en el tratamiento de la EPOC en Atención Primaria

    Microsoft Academic Search

    Mònica Monteagudo; Teresa Rodriguez-Blanco; Judith Parcet; Núria Peñalver; Carles Rubio; Montserrat Ferrer; Marc Miravitlles

    2011-01-01

    BackgroundSeveral studies have approached the use of spirometry in the treatment of chronic obstructive pulmonary disease (COPD) in Primary Care (PC), but few have analysed its impact on the treatment of the patient with COPD.

  19. Efecto de la terapia de locomoción refleja combinada con el tratamiento de fisioterapia en lesión medular. Presentación de un caso

    Microsoft Academic Search

    L. Perales López; A. García Heras; I. Delgado; M. Lara Romero

    2011-01-01

    To analyze the effects of inclusion within a Vojta Therapy protocol in the physiotherapy program of a case with a spinal cord injury. A Patient with 6-month old C3-C6 incomplete spinal cord injury, ASIA Scale C. The ASIA Scale sensory-motor assessment, the Walking Index for Spinal Cord Injury, version 2 (Wisci II) Scale for gait analysis and Barthel Scale for

  20. Disminución del dolor y el peso durante el tratamiento de fisioterapia en pacientes intervenidos de prótesis de rodilla

    Microsoft Academic Search

    J. Fortuño Godes; M. Martín Baranera; E. Kadar García; I. Redondo Parra; B. Gallardo Perez

    2010-01-01

    Pain of recently operated patients for total knee prosthesis is the main problem during the first phase of physiotherapy, which is faster and more efficient in non-overweight patients. We performed a randomized clinical trial to demonstrate pain and body weight reduction in obese patients undergoing knee prosthesis through daily biorhythms and physiological protocolized nutrition, exercise, hydration and rest during the

  1. Papel del farmacéutico de hospital en la prevención, identificación y manejo de los efectos adversos asociados al tratamiento antirretroviral

    Microsoft Academic Search

    R. Morillo Verdugo; L. C. Fernández Lisón; M. J. Huertas Fernández; M. T. Martín Conde; J. C. Roldan Morales; R. Ruano Camps; J. I. Serrano López De Las Hazas; O. Ibarra Barrueta; A. Illaro Uranga

    2010-01-01

    At present, the side effects associated with antiretroviral treatment are the main reasons for discontinuation of this kind of therapy, both in clinical trials and in regular clinical practise.On the other hand, due to the change of direction that our profession has suffered in recent years, we face the need to establish a different relationship with the patient, achieving direct

  2. Consenso SER sobre la gestión de riesgo del tratamiento con terapias biológicas en pacientes con enfermedades reumáticas

    Microsoft Academic Search

    Juan Gómez Reino; Estíbaliz Loza; José Luis Andreu; Alejandro Balsa; Enrique Batlle; Juan D. Cañete; Eduardo Collantes Estévez; Cristina Fernández Carballido; José Luis Fernández Sueiro; Rosario García de Vicuña; Isidoro González-Álvaro; Carlos González Fernández; Xavier Juanola; Luis Francisco Linares; José Luis Marenco; Emilio Martín Mola; Manuel Moreno Ramos; Juan Mulero Mendoza; Santiago Muñoz Fernández; Rubén Queiro; Patricia Richi Alberti; Jesús Sanz; Jesús Tornero Molina; Pedro Zarco Montejo; Loreto Carmona

    2011-01-01

    ObjectiveDue to the increasing use of biologic therapy in rheumatic diseases and the importance of its risk management, the Spanish Society of Rheumatology (SER) has promoted the development of recommendations based on the best evidence available. These recommendations should be a reference to rheumatologists and those involved in the treatment of patients who are using, or about to use biologic

  3. Characterization of the role of CD8 + T cells in breast cancer immunity following mammaglobin-A DNA vaccination using HLA-class-I tetramers

    Microsoft Academic Search

    Ankit Bharat; Nicholas Benshoff; Timothy P. Fleming; Jill R. Dietz; William E. Gillanders; T. Mohanakumar

    2008-01-01

    Introduction  Mammaglobin-A(mam-A) is expressed in over 80% of human breast tumors. We recently reported that mam-A DNA vaccination resulted\\u000a in breast cancer immunity in a preclinical model. Here we investigated whether mam-A HLA-class-I tetramers could be used to\\u000a monitor and define the role of CD8+cytotoxic T-lymphocytes(CTL) in mediating breast cancer immunity following mam-A DNA vaccination.\\u000a \\u000a \\u000a \\u000a Study Design  Mam-A DNA vaccination was performed

  4. American College of Nurse-Midwives

    MedlinePLUS

    ... Tue, 09 Jun 2015 The American College of Nurse-Midwives Wins 2015 Gold Circle Video Award for ... Fri, 01 May 2015 The American College of Nurse-Midwives Consults on New Birth Documentary: The Mama ...

  5. de los expertos y controversias en

    E-print Network

    St Andrews, University of

    hormonal en 2006 9 Misericordia Guinot Gasull Epidemiología y expectativas actuales en el cáncer de mama 13 Martínez Torena La publicación del Childhood Cancer Survivor Study1 confirmó la presunción de que las

  6. Anatoma de los pulmones Pulmn Pleura

    E-print Network

    Kaski, Samuel

    de cáncer pulmonar que de cáncer de colon, de mama y de próstata, combinando estos tres. En 2007 seAmericanadelCáncer www.cancer.gov/cancerinfo /wyntk/lung ·AsociaciónAmericanadeNeumología www.lungusa.org ·Sociedadde

  7. Study of urinary 2-{[2-(acetylamino-2-carboxyethyl]sulfanyl}butanedioic acid, a mercapturic acid of rats treated with maleic acid.

    PubMed

    Luo, Yu-Syuan; Tsai, Hsin-Yun; Chen, Hsin-Chang; Wu, Charlene; Shen, Li-Ching; Chung, Wen-Sheng; Chiang, Su-Yin; Wu, Kuen-Yuh

    2015-08-01

    Maleic anhydride was reported illegally adulterated into starch to prepare traditional foods for decades in Taiwan. Maleic acid (MA), hydrolyzed from maleic anhydride, could cause kidney damages to animals. The potential health effects due to long-term MA exposures through food consumption have been of great concerns. Assessment of the dietary MA exposures could be very difficult and complicated. One of the alternatives is to analyze an MA-specific biomarker to assess the daily total MA intake. Therefore, this paper aimed to study the mercapturic acid of MA, 2-{[2-(acetylamino)-2-carboxyethyl]sulfanyl}butanedioic acid (MAMA), with our newly-developed isotope-dilution online solid-phase extraction liquid chromatography tandem mass spectrometry (ID-SPE-LC-MS/MS) method. MAMA was first synthesized, purified, and characterized with NMR to reveal two diastereomers and used for developing the analytical method. The method was validated to reveal excellent sensitivity with a LOD at 16.3ng/mL and a LOQ at 20.6ng/mL and used to analyze MAMA in urine samples collected from Sprague-Dawley rats treated with a single dose of 0mg/kg, 6mg/kg, and 60mg/kg (n=5) of MA through gavage. Our results show dose-dependent increases in urinary MAMA contents, and 70% MAMA was excreted within 12h with no gender differences (p>0.05). A half life of urinary MAMA was estimated at 6.8h for rat. The formation of urinary MAMA validates it as a chemically-specific biomarker for current MA exposure. Future study of MA metabolism in vivo will elucidate mechanisms of MAMA formation, and analysis of this marker in epidemiology studies could help to shed light on the causal effects of MA on human. PMID:25997398

  8. Suspensión oftálmica de propóleos-R: una alternativa en el tratamiento de las oftalmopatias en animales afectivos (Ophthalmic suspension of red propolis: an alternative in affective animals)

    Microsoft Academic Search

    B. Hugues; C. J. Soto

    The propólis is a substance resinousbees of having proven properties medicinal antiinfeccion, analgesic and regenerated, having been an employee in the man and the animals. To consider that it can be an useful alternative in the treatment of the phftalmopatics in affective animals, was carried out a study in 25 dogs and 5 cats that suffered of blefaritis, conjunctivitis of

  9. TRATAMIENTO DE LOS CARCINOMAS DE GLOTIS T1N0 CON RADIOTERAPIA. RESULTADOS DE NUESTRO CENTRO Y UNA REVISIÓN DE LA LITERATURA

    Microsoft Academic Search

    X. LEÓN; M. QUER; C. ORÚS; M. DE VEGA; J. VERGÉS; L. GAÑÁN

    ment of patients with T1N0 glottic squamous cell carcino- ma. Material and methods: Retrospective study of a cohort of 338 patients with T1N0 glottic carcinoma treated with radio- therapy at our institution between 1985-1997. A review of the litera- ture published during the last ten years was carried out. Results: Lo- cal control with radiotherapy in our patients was 82%,

  10. INVESTIGACIÓN DE COCAÍNA EN ORINA Y PELO PÚBICO DE PACIENTES FÁRMACODEPENDIENTES BAJO TRATAMIENTO AMBULATORIO *Asdrúbal Lárez. Toxicólogo-Asesor Coordinadora Estadal-Aragua Contra Uso Ilícito de

    Microsoft Academic Search

    Simón Pineda; Elizabeth Henríquez; José Carrasquel; Fac. Ciencias

    The present study is based in a quanti qualitative investigation of cocaine in urine and pubic hair from six masculine patients treated in the rehabilitation center (Foundation José Félix Ribas. Maracay. Venezuela). The technique used for in urine was Inmuno Polarized Fluorescence (TDX); in pubic hair the technique applied was Ultraviolet Spectrophotometry (U.V) and gas chromatography-mass spectrometry (CG-MS). The results

  11. EFECTO DE TRATAMIENTOS CUARENTENARIOS, COMBINANDO FRÍO Y ATMÓSFERAS INSECTICIDAS, SOBRE LA FISIOLOGÍA Y LA CALIDAD NUTRICIONAL Y SENSORIAL DE MANDARINAS 'CLEMENULES

    Microsoft Academic Search

    Cristina Rojas-Argudo; Lluis Palou; Adriana Contreras; M. Bernardita Pérez-Gago; Alicia Marcilla

    2007-01-01

    There is a need to develop new postharvest technologies that contribute to maintain the nutritional and sensory quality of fresh fruits and vegetables. The presence of vitamin C and other bioactive components, most of them with antioxidant activity, in citrus fruits gives them an important nutritional value. The application of quarantine treatments, such as low temperature exposure, might affect their

  12. Cistoprostatectomía radical con preservación neurovascular para el tratamiento del cáncer vesical. Relación con la disfunción eréctil: revisión de la literatura científica

    Microsoft Academic Search

    F. Javier González García; Javier Angulo Cuesta

    2009-01-01

    Radical cystectomy (RC) with bilateral pelvic lymph node dissection and urinary diversion remains the gold standard extirpative treatment for high risk non-invasive bladder cancer and muscleinvasive carcinoma. The endpoints after this operation have been historically focused on cure, urethral recurrence and continence. Functional outcomes in radical cystectomy patients were not considered until the middle eighties, thus the evaluation of these

  13. AFRONTAMIENTO PSICOLÓGICO DE LOS PROCEDIMIENTOS MÉDICOS INVASIVOS Y DOLOROSOS APLICADOS PARA EL TRATAMIENTO DEL CÁNCER INFANTIL Y ADOLESCENTE: LA PERSPECTIVA COGNITIVO- CONDUCTUAL

    Microsoft Academic Search

    Juan Manuel Ortigosa; Francisco Xavier Méndez; Antonio Riquelme

    2009-01-01

    Psychological coping with childhood cancer involves the use of strategies and re- sources that help children and their families undergo the disease with the fewest possible emotional and behavioural problems. In the fi eld of Psychology, techniques and programs have been developed and adapted with the aim of minimising the psychological impact of the diagnosis and treatment of childhood and

  14. Tratamiento de la psoriasis del cuero cabelludo. Revisión de la evidencia y Consenso Delphi del Grupo de Psoriasis de la Academia Española de Dermatología y Venereología

    Microsoft Academic Search

    L. Puig; M. Ribera; J. M. Hernanz; I. Belinchón; J. Santos-Juanes; M. Linares; I. Querol; E. Colomé; G. Caballé

    2010-01-01

    Scalp lesions are common in psoriasis and difficult to treat. Scientific evidence on the topic is scant and fragmentary, especially with respect to long-term treatment. This consensus statement is based on a critical assessment of the results of a MEDLINE search for clinical trials of the efficacy and safety of therapies used to treat scalp psoriasis. The recommendations were developed

  15. Testing road surface treatments to reduce erosion in forest roads in Honduras [Tratamientos de la superficie de rodadura para reducir la erosion en caminos forestales en Honduras

    USGS Publications Warehouse

    Rivera, Samuel; Kershner, Jeffrey L.; Keller, Gordon R.

    2009-01-01

    Testing road surface treatments to reduce erosion in forest roads in Honduras. Cien. Inv. Agr. 36(3):425-432. Using forest roads produces more erosion and sedimentation than any other forest or agricultural activity. This study evaluated soil losses from a forest road in central Honduras over two consecutive years. We divided a 400-m segment of road into 8 experimental units, each 50 m in length. Four units were treated with Best Management Practices (BMPs) and four were left untreated. The BMP treatments included reshaping the road prism, installing culverts and reshaping of road ditches, compacting 20-cm layers of the road tread, crowning the road surface (3% slope, double drainage), longitudinal sloping (less than 12%), and adding a 10-cm layer of gravel (crush size = 0.63 cm). Soil movement was measured daily during the rainy seasons. The highest soil loss occurred in the control road, around 500 m3 km-1 per year, while the road treated with BMP lost approximately 225 m3km-1 per year. These results show that road surface erosion can be reduced up to 50% with the implementation of surface treatments.

  16. Evaluación económica de rituximab en combinación con fludarabina y ciclofosfamida en comparación con fludarabina y ciclofosfamida en el tratamiento de la leucemia linfática crónica

    Microsoft Academic Search

    Luis Felipe Casado; José Antonio García Marco; Florinda Gilsanz; Marcos González; Eduardo Ríos; Javier de la Serna; Álvaro Urbano; Vicente Vicente; Carlos Rubio-Terrés; Antonio J. Castro

    2011-01-01

    ObjectivesWe evaluated the cost-effectiveness of rituximab added to the chemotherapy regimen of fludarabine plus cyclophosphamide (R-FC) versus fludarabine plus cyclophosphamide (FC) for the treatment of patients with previously untreated or relapsed\\/refractory chronic lymphocytic leukemia (CLL).

  17. Sistema de aspiración-tracción en el tratamiento de la Fasciitis necrotizante del periné * Negative Pressure wound therapy for the treatment of perineal necrotizing fasciitis

    Microsoft Academic Search

    BLAZENKO PUJADO; E. U. MARILDE; E. U. KARINA; PAULA VIDAL

    Introduction: We discuss five patients treated at our institution. Besides the initial surgical debridement and antibiotic therapy, we used the negative-pressure wound therapy (NPWT) as part of their treatment. Patients and methods: The NPWT device was constructed with off-the-shelf components. After the diagnosis of perineal necrotizing fasciitis was established, all patients underwent surgical debridement of necrotic tissue. The wound was

  18. XII SIMPOSIO DE TRATAMIENTO DE SE ~NALES, IM AGENES Y VISI ON ARTIFICIAL. STSIVA 2007 1 On Selecting Middle-Length Feature Lines for

    E-print Network

    Duin, Robert P.W.

    of Engineering and Archi- tecture, National University of Colombia at Manizales, Kil´ometro 7 V´ia al Aeropuerto, Campus La Nubia - Bloque Q, piso 2, Manizales (Caldas), Colombia. See http://www.docentes.unal.edu.co/morozcoa/ or http://orozco.co.nr/ for contact details. Robert P. W. Duin is with the Information and Communication

  19. Fundamentos del rechazo a la transfusión sanguínea por los Testigos de Jehová. Aspectos ético-legales y consideraciones anestésicas en su tratamiento

    Microsoft Academic Search

    A. Pérez Ferrer; E. Gredilla; J. de Vicente; J. García Fernández; F. Reinoso Barbero

    Summary The refusal of Jehovah's Witnesses to agree to blood or blood product transfusion based on religious beliefs is one of the most challenging conflictive issues health care givers have to face today. Such conflict is a by product of the ideological and religious diversity in society today. The perioperative care of such patients constitutes a genuine challenge for anesthesiologists

  20. 12. Laboratoris de recerca 12.1. Laboratori de Conducta i Sistemes Dinmics (LabCSD)

    E-print Network

    Oro, Daniel

    tratamiento del trastorno por déficit de atención e hiperactividad frente a los tratamientos estándar-12711) -- Desarrollo y validación de un programa de e-terapia inteligente para el tratamiento del trastorno de ansiedad

  1. Flaxseed oil enhances the effectiveness of trastuzumab in reducing the growth of HER2-overexpressing human breast tumors (BT-474).

    PubMed

    Mason, Julie K; Fu, Minghua; Chen, Jianmin; Thompson, Lilian U

    2015-01-01

    Flaxseed oil (FSO) reduces breast tumorigenesis and HER2 expression in animal models of luminal breast cancer. The primary treatment for HER2-overexpressing tumors is trastuzumab (TRAS). We aimed to determine the effect of 4% FSO alone and combined with TRAS on HER2-overexpressing tumor (BT-474) growth and to explore potential mechanisms with a specific focus on HER2, mitogen-activated protein kinase (MAPK) and Akt signaling and fatty acid profile. Athymic mice with established tumors were fed the basal diet (control) or 4% FSO diet, with or without TRAS (1 or 2.5 mg/kg) treatment for 4 weeks. Tumor growth, HER2 signaling biomarkers (mRNA and protein) and fatty acid profile were measured. Tumors treated with FSO alone showed no difference in tumor growth compared to control; however, compared to TRAS2.5 and other groups, FSO+TRAS2.5 caused significantly lower tumor growth and cell proliferation and higher apoptosis and the greatest lowering of signaling biomarker expressions (MAPK2, HER2 mRNA; pHER2 protein). Both TRAS and FSO had main effects of reducing the phosphorylated/total expression of Akt and MAPK protein expression. Dietary FSO altered the tumor fatty acid profile. In conclusion, 4% dietary FSO alone does not affect BT-474 tumor growth but enhances the tumor-reducing effect of TRAS (2.5 mg/kg). FSO×TRAS interactive effect may be modulated by their combined reductions of HER2 signaling through the Akt and MAPK pathways leading to reduced cell proliferation and increased apoptosis. FSO alters tumor fatty acid profile that likely contributes to effects on signaling pathways. This supports FSO as a complementary treatment for HER2+ breast cancer treated with TRAS. PMID:25441844

  2. Preparation and structural characterization of a novel monoamine monoamide bisthiol metal oxo complex with technetium(V) and rhenium(V)

    SciTech Connect

    O`Neil, J.P.; Wilson, S.R.; Katzenellenbogen, J.A. [Univ. of Illinois, Urbana, IL (United States)

    1993-12-31

    In connection with the interest in the preparation of technetium and rhenium labeled steroids as agents for the diagnosis and therapy of breast cancer, the authors have developed a novel monoamine monoamide bisthiol (MAMA) chelate system. Stepwise N-alkylation of S-trityl protected 2-aminoethanethiol with bromacetyl bromide gave protected MAMA ligand 1 which then underwent N-benzylation to form S,S`-bistrityl protected chelate 2. Deprotection followed by metal incorporation provided metal(V) oxo complexes 3-6 (M = Re, {sup 99}Tc). The diastereoisomers of these compounds have been separated and characterized by X-ray crystallography as well as 2D-NMR.

  3. Problemas sexuales y de fecundidad (hombres)

    Cancer.gov

    Muchos tratamientos del cáncer y algunos tipos de cáncer pueden causar efectos secundarios relacionados con la sexualidad y con la fecundidad. Ya sea que usted tenga o no estos problemas depende del tipo de tratamiento que recibe, de su edad al tiempo del tratamiento y del tiempo que ha pasado desde el tratamiento.

  4. Influence of postharvest hot-dip fungicide treatments on Redblush grapefruit quality during long-term storage\\/Efecto de los tratamientos fungicidas postcosecha por inmersión en agua caliente sobre la calidad del pomelo Redblush durante el almacenamiento en frío

    Microsoft Academic Search

    M. Schirra; M. Mulas; L. Baghino

    1995-01-01

    The efficacy of postharvest hot-dip treatment on Redblush grapefruit was investigated by 3-min dips in water at 50°C and 20°C, with and without 1500 ppm imazalil (IMZ) or thiabendazole (TBZ). Fruits were stored for 16 weeks in cold rooms at 8°C and then held at 20°C for 1 week to simulate shelf life. IMZ and TBZ treatment at 20°C considerably

  5. Realidad Virtual: Un Aporte Real para la Evaluación y el Tratamiento de Personas con Discapacidad Intelectual1 Virtual Reality: A Real Contribution for the Evaluation and Treatment of People with Intelectual Disability

    Microsoft Academic Search

    Claudia P. Pérez-Salas

    Virtual Reality is a particular computational simulation which allows recreating real environments where the subject is able to interact and live the experience as it were in a real setting. This article presents the principal applications of this technology in the design of environments for assessment and intervention of intellectually disabled persons, focusing in the advantages of Virtual Reality for

  6. Resistencia al tratamiento de primera línea de quimioterapia en un paciente diagnosticado de linfoma de Hodgkin de predominio linfocítico nodular identificada mediante 18F-FDG PET\\/TAC: implicaciones diagnósticas y terapéuticas

    Microsoft Academic Search

    J. Banzo; M. A. Ubieto; P. Giraldo; P. Razola; E. Prats; L. Tardin; A. Santapau; A. Parra; E. F. Rambalde; J. Velilla

    Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) is a rare entity that accounts for less than 5% of the cases of Hodgkin lymphoma (HL) with morphological, immunophenotypical, genetic and clinical behavior traits different from the classic HL. In a minority of patients, the NLPHL course is complicated by a transformation to a non-Hodgkin diffuse large B-cell lymphoma (NHDLBCL) with prognostic and therapeutic

  7. NORMATIVA CONTABLE ADOPTADA EN EL TRATAMIENTO DE OPERACIONES CON INSTRUMENTOS DERIVADOS: EVIDENCIA EMPÍRICA EN EL MERCADO DE CAPITALES PORTUGUÉS ACCOUNTING STANDARDS FOR TRANSACTIONS WITH DERIVATIVE INSTRUMENTS: EMPIRICAL EVIDENCE IN THE

    Microsoft Academic Search

    KÁTIA MATOS LEMOS; LÚCIA LIMA RODRIGUES

    In a context characterized by some uncertainty about the standards that should be adopted to account for derivative instruments, it is understandable that Portuguese companies do not follow the same rules in the initial recognition and later evaluation of these instruments and that the information they provide is so heterogeneous. Thus, this study investigates how Portuguese companies report their derivative

  8. The Next UV Spectrograph for the Hubble Space Telescope

    E-print Network

    Colorado at Boulder, University of

    atmospheres and comets in our Solar System (and beyond)? COS will help answer some fundamental questions: #12 light onto three separate regions on a 25x25 mm Multi Anode Microchannel Array (MAMA) detector to fringes created by the interference of two coherent laser beams chemical treatment of the photosensitive

  9. Paul Cristofano Cusco, Peru-Summer 2010

    E-print Network

    Paul Cristofano Cusco, Peru-Summer 2010 #12;Over the summer, I spent 6 weeks volunteering in Cusco, Peru. Cusco is one of the biggest cities in Peru. It is known for its deep culture as well as tourism of Peru, Pacha Mama. #12;We lived with a host family in a nice section of town. Our host parents Sonia

  10. Homeschoolers on to College: What Research Shows Us

    ERIC Educational Resources Information Center

    Ray, Brian D.

    2004-01-01

    Experience and anecdotes have led many people to believe that homeschool parents were either move-to-the-country anarchist goat-herders, or right-wing Bible-thumpers, and their children were either mathematically-limited, due to Mama's fear of math, or child prodigies in rocket-science who were unthinkably socially hindered. Although one can find…

  11. Visión de un científico oncólogo que aplica la investigación a la salud humana a través de las fronteras

    Cancer.gov

    El doctor Jorge Gómez es el asesor principal del Centro para la Salud Mundial del Instituto Nacional del Cáncer. Dirige la Red de Investigación del Cáncer de los Estados Unidos y América Latina, la cual está realizando un estudio internacional de los factores de riesgo del cáncer de mama y características en las mujeres de América Latina.

  12. Aplicação da microcirurgia no serviço de cirurgia plástica da universidade federal da bahia: análise dos resultados e complicações

    Microsoft Academic Search

    Marcelo Sacramento Cunha; Rogério dos Santos Ramos; André Leal Gonçalves Torres; Deise de Azevedo Monteiro e Souza; Ivan Marcelo Gonçalves Agra; José Neiva Eulálio

    2005-01-01

    RESUMO: Objetivo: O estudo pretende relatar a experiência inicial de um serviço de cirurgia plástica ao implantar um grupo de microcirurgia, analisando as complicações e resultados da casuística. Método: No período de fevereiro de 2003 a junho de 2004, foram realizados 20 procedimentos de microcirurgia reconstrutiva variando em reconstruções de cabeça e pescoço, mama e membros inferi ores. As complicações

  13. A new analytical approach to estimate the hydraulic parameters of a coastal phreatic aquifer from tidally induced water table fluctuations and its application at the Niijima Island, Japan

    Microsoft Academic Search

    M. Aichi; M. Shiokari; T. Tokunaga

    2010-01-01

    A new perturbation solution of the Boussinesq equation for tidally induced water table fluctuations in a coastal phreatic aquifer was derived under the condition of multiple tidal constituents. Then, the obtained solution was applied to estimate hydraulic parameters of the Shiro-mama formation at the Niijima Island, Japan, by fitting the solution to the results of continuous measurements of water table

  14. A Mobile App to Automatically Detect and Report Children's Location

    E-print Network

    Runapongsa, Kanda

    of Engineering Khon Kaen University, Khon Kaen, Thailand chaluemwut@hotmail.com, polpinit@kku.ac.th, somkaw@gmail, the web application allows parents to add and remove tracking devices, as well as, to check the history. Children can check-in to let their parents know their location in Sygic Family and MamaBear. Finally, Sygic

  15. The Author 2012. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com

    E-print Network

    Gleeson, Joseph G.

    , please e-mail: journals.permissions@oup.com Human Milk Oligosaccharides: Every Baby needs a Sugar Mama Oligosaccharides (HMO) are a family of structurally diverse unconjugated glycans that are highly abundant the postulated beneficial effects of HMO for the breast-fed neonate, compares HMO to oligosaccharides in the milk

  16. Temporal Regularization Use in Dynamic Contrast-Enhanced MRI

    E-print Network

    Fessler, Jeffrey A.

    . Khalsa 2011 All Rights Reserved #12;To my mama. You are the strongest woman I know. ii #12 Research Fellowship Program, the Department of Defense Breast Cancer Research Predoctoral Traineeship.1 Motivation: Application to Breast Cancer . . . . . . . . . . . 1 1.2 Tradeoff betwe

  17. Romans: A Simulation of the History and Culture of Ancient Rome.

    ERIC Educational Resources Information Center

    Staneart, Chuck; Baral, Wanda

    This simulation allows students to learn about and participate in many of the aspects of ancient Roman life that have influenced present institutions and way of life. The phases of the unit include: (1) "Daily Life"; (2) "Forum of Roma"; (3) "Temple of Apollo"; (4) "Pax Romana"; (5) "History/Mystery: 'Who Killed Mama Roma?'"; (6) "Circus Maximus"…

  18. Minimum audible movement angles as a function of sound source trajectory.

    PubMed

    Saberi, K; Perrott, D R

    1990-12-01

    Auditory resolution of moving sound sources was determined in a simulated motion paradigm for sources traveling along horizontal, vertical, or oblique orientations in the subjects's frontal plane. With motion restricted to the horizontal orientation, minimum audible movement angles (MAMA) ranged from about 1.7 degrees at the lowest velocity (1.8 degrees/s) to roughly 10 degrees at the highest velocity (320 degrees/s). With the sound moving along an oblique orientation (rotated 45 degrees relative to the horizontal) MAMAs generally matched those of the horizontal condition. When motion was restricted to the vertical, MAMAs were substantially larger at all velocities (often exceeding 8 degrees). Subsequent tests indicated that MAMAs are a U-shaped function of velocity, with optimum resolution obtained at about 2 degrees/s for the horizontal (and oblique) and 7-11 degrees/s for the vertical orientation. Additional tests conducted at a fixed velocity of 1.8 degrees/s along oblique orientations of 80 degrees and 87 degrees indicated that even a small deviation from the vertical had a significant impact on MAMAs. A displacement of 10 degrees from the vertical orientation (a slope of 80 degrees) was sufficient to reduce thresholds (obtained at a velocity of 1.8 degrees/s) from about 11 degrees to approximately 2 degrees (a fivefold increase in acuity). These results are in good agreement with our previous study of minimum audible angles long oblique planes [Perrott and Saberi, J. Acoust. Soc. Am. 87, 1728-1731 (1990)].(ABSTRACT TRUNCATED AT 250 WORDS) PMID:2283437

  19. Minimum audible movement angle in the horizontal plane as a function of stimulus frequency and bandwidth, source azimuth, and velocity.

    PubMed

    Chandler, D W; Grantham, D W

    1992-03-01

    Minimum audible movement angles (MAMAs) were measured in the horizontal plane for four normal-hearing adult subjects in a darkened anechoic chamber. On each trial, a single stimulus was presented, and the subject had to say whether it came from a stationary loudspeaker or from a loudspeaker that was moving at a constant angular velocity around him. Thresholds were established by adaptively varying stimulus duration. In experiment 1, MAMAs were measured as a function of center frequency (500-5000 Hz), velocity (10 degrees-180 degrees/s), and direction of motion (left versus right). There was no effect of direction of motion. MAMAs increased with velocity, from an average of 8.8 degrees of arc for a target moving at 10 degrees/s to an average of 20.2 degrees of arc for a target moving at 180 degrees/s. MAMAs were higher for a 3000-Hz tone than for tones of lower or higher frequencies, as has been previously reported [D. R. Perrott and J. Tucker, J. Acoust. Soc. Am. 83, 1522-1527 (1988)]. In experiment 2, minimum audible angles (MAAs) were measured with sequentially presented stationary tone pulses (500-5000 Hz), and were shown to exhibit the same dependence on signal frequency that the MAMAs showed (average MAA at 3000 Hz: 8.4 degrees; average MAA at the other frequencies: 3.4 degrees). In experiment 3, MAMAs and MAAs were measured as a function of stimulus bandwidth (centered at 3000 Hz) and listening azimuth (0 degrees vs 60 degrees). Average MAAs decreased monotonically as stimulus bandwidth increased from 0 Hz to wideband (from 8.4 degrees to 1.2 degrees at 0 degrees azimuth; from 11.3 degrees to 1.5 degrees at 60 degrees azimuth). As in experiment 1, MAMAs increased with stimulus velocity, from values comparable to the MAAs for the slowest-velocity (10 degrees/s) targets to 70 degrees of arc or more in the poorest condition (third-octave band of noise presented at a velocity of 180 degrees/s and an azimuth of 60 degrees). MAMAs obtained in the slower-velocity conditions depended in the same way on stimulus bandwidth and listening azimuth that MAAs depended on these variables. In no case was the MAMA ever smaller than the MAA. It is hypothesized that a minimum integration time is required to achieve optimal performance in a dynamic spatial resolution task. Average estimates of this minimum time based on the current data vary from 336 ms (for targets presented at midline) to 1116 ms (for narrow-band targets presented at 60 degrees azimuth).(ABSTRACT TRUNCATED AT 400 WORDS) PMID:1564199

  20. Radioterapia

    Cancer.gov

    La radioterapia es un tratamiento del cáncer que usa altas dosis de radiación para destruir células cancerosas y reducir tumores. Aprenda los diferentes tipos de radiación y lo que usted puede esperar del tratamiento.

  1. Prurito –para profesionales de salud (PDQ®)

    Cancer.gov

    Resumen de información revisada por expertos acerca del prurito (picazón de la piel) como complicación a causa del cáncer y su tratamiento. Se discuten los enfoques del manejo y tratamiento del prurito.

  2. Dolor–para profesionales de salud (PDQ®)

    Cancer.gov

    Resumen de información revisada por expertos acerca del dolor como una complicación a causa del cáncer o su tratamiento. Se discuten enfoques sobre el manejo y tratamiento del dolor relacionado con el cáncer.

  3. New Developments in the Technology Readiness Assessment Process in US DOE-EM - 13247

    SciTech Connect

    Krahn, Steven [Department of Civil and Environmental Engineering, Vanderbilt University, Nashville, TN, 37235 (United States)] [Department of Civil and Environmental Engineering, Vanderbilt University, Nashville, TN, 37235 (United States); Sutter, Herbert [Consultant, 910 Laurel Green Dr., North Canton, OH, 44720 (United States)] [Consultant, 910 Laurel Green Dr., North Canton, OH, 44720 (United States); Johnson, Hoyt [DOE-EM, 1000 Independence Ave., Washington, DC, 20585 (United States)] [DOE-EM, 1000 Independence Ave., Washington, DC, 20585 (United States)

    2013-07-01

    A Technology Readiness Assessment (TRA) is a systematic, metric-based process and accompanying report that evaluates the maturity of the technologies used in systems; it is designed to measure technology maturity using the Technology Readiness Level (TRL) scale pioneered by the National Aeronautics and Space Administration (NASA) in the 1980's. More recently, DoD has adopted and provided systematic guidance for performing TRAs and determining TRLs. In 2007 the GAO recommended that the DOE adopt the NASA/DoD methodology for evaluating technology maturity. Earlier, in 2006-2007, DOE-EM had conducted pilot TRAs on a number of projects at Hanford and Savannah River. In March 2008, DOE-EM issued a process guide, which established TRAs as an integral part of DOE-EM's Project Management Critical Decision Process. Since the development of its detailed TRA guidance in 2008, DOE-EM has continued to accumulate experience in the conduct of TRAs and the process for evaluating technology maturity. DOE has developed guidance on TRAs applicable department-wide. DOE-EM's experience with the TRA process, the evaluations that led to recently developed proposed revisions to the DOE-EM TRA/TMP Guide; the content of the proposed changes that incorporate the above lessons learned and insights are described. (authors)

  4. Loss-of-function and gain-of-function phenotypes of stomatocytosis mutant RhAG F65S

    PubMed Central

    Stewart, Andrew K.; Shmukler, Boris E.; Vandorpe, David H.; Rivera, Alicia; Heneghan, John F.; Li, Xiaojin; Hsu, Ann; Karpatkin, Margaret; O'Neill, Allison F.; Bauer, Daniel E.; Heeney, Matthew M.; John, Kathryn; Kuypers, Frans A.; Gallagher, Patrick G.; Lux, Samuel E.; Brugnara, Carlo; Westhoff, Connie M.

    2011-01-01

    Four patients with overhydrated cation leak stomatocytosis (OHSt) exhibited the heterozygous RhAG missense mutation F65S. OHSt erythrocytes were osmotically fragile, with elevated Na and decreased K contents and increased cation channel-like activity. Xenopus oocytes expressing wild-type RhAG and RhAG F65S exhibited increased ouabain and bumetanide-resistant uptake of Li+ and 86Rb+, with secondarily increased 86Rb+ influx sensitive to ouabain and to bumetanide. Increased RhAG-associated 14C-methylammonium (MA) influx was severely reduced in RhAG F65S-expressing oocytes. RhAG-associated influxes of Li+, 86Rb+, and 14C-MA were pharmacologically distinct, and Li+ uptakes associated with RhAG and RhAG F65S were differentially inhibited by NH4+ and Gd3+. RhAG-expressing oocytes were acidified and depolarized by 5 mM bath NH3/NH4+, but alkalinized and depolarized by subsequent bath exposure to 5 mM methylammonium chloride (MA/MA+). RhAG F65S-expressing oocytes exhibited near-wild-type responses to NH4Cl, but MA/MA+ elicited attenuated alkalinization and strong hyperpolarization. Expression of RhAG or RhAG F65S increased steady-state cation currents unaltered by bath Li+ substitution or bath addition of 5 mM NH4Cl or MA/MA+. These oocyte studies suggest that 1) RhAG expression increases oocyte transport of NH3/NH4+ and MA/MA+; 2) RhAG F65S exhibits gain-of-function phenotypes of increased cation conductance/permeability, and loss-of-function phenotypes of decreased and modified MA/MA+ transport, and decreased NH3/NH4+-associated depolarization; and 3) RhAG transports NH3/NH4+ and MA/MA+ by distinct mechanisms, and/or the substrates elicit distinct cellular responses. Thus, RhAG F65S is a loss-of-function mutation for amine transport. The altered oocyte intracellular pH, membrane potential, and currents associated with RhAG or RhAG F65S expression may reflect distinct transport mechanisms. PMID:21849667

  5. Platiquemos un rato...

    Cancer.gov

    1 La historia de Ana Y cómo ella recibió tratamiento para el cáncer 2 Ana tiene cáncer. 3 “Existen muchos tratamientos para el cáncer”, dijo su médico. 4 Le dio un folleto acerca de un estudio clínico, una opción para el tratamiento del cáncer. 5 Un estudio

  6. Successful endovascular treatment of transplant intrarenal artery stenosis in renal transplant recipients: Two case reports.

    PubMed

    Koukoulaki, Maria; Brountzos, Elias; Loukopoulos, Ioannis; Pomoni, Maria; Antypa, Eleni; Vougas, Vasileios; Drakopoulos, Spiros

    2015-06-24

    Transplant renal artery stenosis (TRAS) is a relatively rare complication after renal transplantation. The site of the surgical anastomosis is most commonly involved, but sites both proximal and distal to the anastomosis may occur, as well. Angioplasty is the gold standard for the treatment of the stenosis, especially for intrarenal lesions. We report two cases of intrarenal TRAS and successful management with angioplasty without stent placement. Both patients were male, 44 and 55 years old respectively, and they presented with elevated blood pressure or serum creatinine within three months after transplantation. Subsequently, they have undergone angioplasty balloon dilatation with normalization of blood pressure and serum creatinine returning to baseline level. Percutaneous transluminal balloon renal angioplasty is a safe and effective method for the treatment of the intrarenal TRAS. PMID:26131408

  7. Successful endovascular treatment of transplant intrarenal artery stenosis in renal transplant recipients: Two case reports

    PubMed Central

    Koukoulaki, Maria; Brountzos, Elias; Loukopoulos, Ioannis; Pomoni, Maria; Antypa, Eleni; Vougas, Vasileios; Drakopoulos, Spiros

    2015-01-01

    Transplant renal artery stenosis (TRAS) is a relatively rare complication after renal transplantation. The site of the surgical anastomosis is most commonly involved, but sites both proximal and distal to the anastomosis may occur, as well. Angioplasty is the gold standard for the treatment of the stenosis, especially for intrarenal lesions. We report two cases of intrarenal TRAS and successful management with angioplasty without stent placement. Both patients were male, 44 and 55 years old respectively, and they presented with elevated blood pressure or serum creatinine within three months after transplantation. Subsequently, they have undergone angioplasty balloon dilatation with normalization of blood pressure and serum creatinine returning to baseline level. Percutaneous transluminal balloon renal angioplasty is a safe and effective method for the treatment of the intrarenal TRAS. PMID:26131408

  8. Relationships between plasma and erythrocyte Zn and maturation in adolescent males

    SciTech Connect

    Arquitt, A.B.; Hermann, J.R.; Stoecker, B.J. (Oklahoma State Univ., Stillwater (United States))

    1991-03-15

    Sixty-three male volunteers between the ages of 10.6 and 14.3 yr were assessed for maturation and zinc status. The adrenal androgen dehydroepiandrosterone sulfate (DHEAS), used as a maturation indicator, was significantly correlated with height, weight, hemoglobin, and mid-arm muscle area (MAMA) as previously reported. Erythrocyte Zn (RBC-Zn) and plasma Zn were significantly correlated. When grouped by plasma Zn tertiles, significant differences were found for RBC-Zn and cholesterol between the highest and lowest groups. When subjects were grouped by RBC-Zn concentration, the lowest 10% of subjects had higher concentrations of DHEAS, lower plasma Zn , and were taller, heavier and had larger MAMA than the other group. In these subjects plasma and RBC-Zn concentrations were within normal limits. In this study RBC-Zn and plasma Zn were related to indicators of maturation.

  9. CALACS Reference Files Warren J. Hack

    E-print Network

    Sirianni, Marco

    Ray Rejection ACS2D DQI,Flat,Dark,... CRCORR RPT CORR ACSSUM CCD MAMA Yes Yes ACSCCD (AtoD, DQI, BLEV: Flow diagram for CCD data in CALACS. summed, calibrated image doStat ACSSUM ACS2D doNoise doDQI doNonLin doDark doFlat ACSREJCRREJ? YES NO doShad doPhot raw file ACSCCD doNoise doDQI doAtoD doBlev do

  10. Comments on Spielman's article on Evolutionary Relationships: Guaymi and Yanomama

    E-print Network

    Crawford, Michael H.

    1979-01-01

    specificities of the HLA system in 22 Guaymi. A specificity (HLA Bwl5) absent from the Yano- mama is present in high frequency in the Guaymi. Elsewhere we have reported that a polymorphism of serum albumin in the Yanomama is not present in the Guaymi... to proteins could be responsible tially for dissimilarity between two groups. P3r The authors conclude that further research in conjunction with previously collected genetic and anthropometric data can likely resolve the question of phylogenetic...

  11. The Effects of Images of African American Women in Hip Hop on Early Adolescents’ Attitudes Toward Physical Attractiveness and Interpersonal Relationships

    Microsoft Academic Search

    Dionne P. Stephens; April L. Few

    2007-01-01

    This qualitative study was designed to identify African American early adolescents’ subjective meanings of African American\\u000a women’s sexuality through an examination of Stephens & Phillips (2003) sexual images—the Diva, Gold Digger, Freak, Dyke, Gangster Bitch, Sister Savior, Earth Mother, and Baby Mama. These eight\\u000a sexual images both inform and reflect beliefs about African American women’s physical attractiveness. Interpersonal relationship\\u000a decision

  12. Hip Hop Honey or Video Ho: African American Preadolescents’ Understanding of Female Sexual Scripts in Hip Hop Culture

    Microsoft Academic Search

    Dionne P. Stephens; April L. Few

    2007-01-01

    This qualitative study identifies African American preadolescents’ acceptance and usage of Stephens and Phillips (2003) sexual\\u000a scripts—the Diva, Gold Digger, Freak, Dyke, Gangster Bitch, Sister Savior, Earth Mother, and Baby Mama. These eight sexual\\u000a scripts were found to be recognized and have shared meanings about sexual behaviors for participants. In turn, these were\\u000a found to influence participants’ conceptualizations of their

  13. Transplant Renal Artery Stenosis

    Microsoft Academic Search

    EBERHARD RITZ; SIMONA BRUNO; GIUSEPPE REMUZZI; PIERO RUGGENENTI

    2004-01-01

    Transplant renal artery stenosis (TRAS) is a recog- nized, potentially curable cause of posttransplant arterial hy- pertension, allograft dysfunction, and graft loss. It usually occurs 3 mo to 2 yr after transplantation, but early or later presentations are not uncommon. The prevalence ranges widely from 1 to 23% in different series, reflecting the heter- ogeneous criteria used to establish the

  14. Renal artery stenosis in kidney transplants

    Microsoft Academic Search

    FC Fervenza; RA Lafayette; EJ Alfrey; J Petersen

    1998-01-01

    Transplant renal artery stenosis (TRAS) is an increasingly recognized complication of renal transplantation, with a reported incidence of between 1% and 23%. The clinical features include refractory hypertension, new-onset hypertension, allograft dysfunction, and the presence of a bruit over the graft. In this report, we describe the investigation and treatment of one such patient and review the current diagnostic approaches

  15. Cinvestav en su tinta Oscar Rosas-Ortiz*

    E-print Network

    Rosas-Ortiz, Jose Oscar

    Investigación y de Estudios Avanzados (Cinvestav). Editor de la presente columna. en el James Clerk Maxwell: Una proceso de pensamiento desarrollado por este niño, de nom- bre James Clerk Maxwell, a lo largo de su breve Newton"1 . 1839.John Clerk Maxwell siente un escalofrío mien- tras acaricia la mejilla de su hijo James

  16. El uso de Google Earth para el estudio de la arquitectura hospitalaria (II): los hospitales cruciformes, radiales y pabellonarios

    Microsoft Academic Search

    Quim Bonastra; Gerard Jori

    2009-01-01

    Tras casi quince años de funcionamiento, Google Earth se ha convertido en una herramienta de gran utilidad para la investigación y enseñanza de las ciencias sociales y naturales. La geografía, que tiene la superficie terrestre como principal objeto de estudio, no ha permanecido al margen de este fenómeno, y cada vez es mayor el número de geógrafos que utilizan esta

  17. El uso de Google Earth para el estudio de la arquitectura hospitalaria (I): de los asclepiones a los hospitales medievales

    Microsoft Academic Search

    Quim Bonastra; Gerard Jori

    2009-01-01

    Tras casi quince años de funcionamiento, Google Earth se ha convertido en una herramienta de gran utilidad para la investigación y enseñanza de las ciencias sociales y naturales. La geografía, que tiene la superficie terrestre como principal objeto de estudio, no ha permanecido al margen de este fenómeno, y cada vez es mayor el número de geógrafos que utilizan esta

  18. Malaria: a un paso del fin Para el investigador Quique Bassat hablar de "erradicacin" es posible a largo plazo

    E-print Network

    Geffner, Hector

    1 Malaria: a un paso del fin Para el investigador Quique Bassat hablar de "erradicación" es posible a largo plazo "Tras un fuerte ataque de malaria la persona se convierte en una piltrafa humana, yace. Según la OMS, la malaria, conocida también como paludismo, afecta cada año a unos 210 millones de

  19. UNIVERSIDAD AUTONOMA DE MADRID ESCUELA POLITECNICA SUPERIOR

    E-print Network

    Autonoma de Madrid, Universidad

    reales de iris. Tras una introducción a la biometría, estudio del iris, del estado del arte en attacks to biometric authentication systems using forgery images of real eyes. After a review of the state of the art of biometrics, and more specially of iris-liveness detection systems, we select and implement

  20. Restructurations et rentabilité économique dans l'industrie française de 1985 à 1992

    Microsoft Academic Search

    Elisabeth Kremp

    1995-01-01

    [spa] Reestructuración y rentabilidad econômica en la industria francesa de 1985 a 1992 . por Elisabeth Kremp . En este articulo se analiza el impacto de las operaciones de reestructuración industrial en la rentabilidad económica. Tras haber resumido la literatura existente para sacar los distintos factores que pueden explicar las discrepancias de conclusiones, se examina la vulnerabilidad de los resultados

  1. Estimado/a Isabel Abril Snchez: En primer lugar, queremos agradecerle la participacin en la decimoquinta edicin de Ciencia

    E-print Network

    Escolano, Francisco

    decimoquinta edición de Ciencia en Acción, en la modalidad "Física en la Sociedad". El jurado ha evaluado el trabajo presentado por usted titulado "El Patio de la Ciencia" y ha sido seleccionado como uno de los, verdaderos protagonistas del concurso, Ciencia en Acción se consolida y aumenta su prestigio año tras año. Si

  2. Patrimonio urbano y vivienda social en el centro de Buenos Aires: nuevas perspectivas y conflictos

    E-print Network

    Richner, Heinz

    actividades, entre las cuales una pieza clave fue la rehabilitación de una manzana localizada en el Centro Histórico de Buenos Aires. Pocos meses después se iniciaba la operación de la Manzana de San Francisco, tras la segunda y última etapa de la obra. La "manzana" en cuestión estaba conformada por una serie de

  3. La actuación pública para el fomento de nuevas empresas Hacia un enfoque de política económica

    Microsoft Academic Search

    José Antonio; Belso Martínez

    A lo largo de este trabajo abordaremos la tarea de analizar el perfil de las distintas actuaciones y la potencial existencia de una política econó- mica específica de creación de empresas, tras lo que trataremos de esta- blecer, en su caso, una posible estructura de la misma. Para alcanzar sen- dos propósitos intentaremos: revisar las líneas generales de los diferentes

  4. PLANIFICACIÓN ESTRATÉGICA Y DESARROLLO DEL PROCESO DE APRENDIZAJE-EVALUACIÓN PARA LA ADQUISICIÓN DE COMPETENCIAS EN EL GRADO DE DERECHO A TRAVÉS DE LA GUÍA DOCENTE Y LA PLATAFORMA MOODLE

    Microsoft Academic Search

    Juan Antonio Chinchilla Peinado; Lucía López De Castro García-Morato

    2012-01-01

    El presente artículo versa sobre el diseño y desarrollo del proceso de aprendizaje-evaluación para la adquisición de competencias por los estudiantes en la asignatura de Instituciones de la Unión Europea, del primer curso del Grado de Derecho de la Universidad Autónoma de Madrid, cuya docencia acaba de completarse en el curso académico 2010-2011. De esta forma, tras unas consideraciones generales

  5. Pueblos indígenas y desarrollo sostenible: El papel del Banco Interamericano de Desarrollo

    Microsoft Academic Search

    Anne Deruyttere

    1997-01-01

    Esta presentación se centra en el papel que desempeña el Banco Interamericano de Desarrollo en el desarrollo socioeconómico de los pueblos indígenas de América Latina. Tras una descripción de cómo están integrados los pueblos indígenas de la región y de los temas y preocupaciones que encaran, se exponen los lineamientos generales de un documento de breve estrategia más detallado que

  6. Prevalencia de trastornos psiquiátricos en Latinoamérica: revisión crítica

    Microsoft Academic Search

    Benjamín Vicente; Pedro Rioseco; Sandra Saldivia; Robert Kohn; Silverio Torres

    2005-01-01

    Introducción: La forma como se conducen las investigaciones en epidemiología psiquiátrica en América Latina ha impedido que los resultados sean ampliamente conocidos; además, se han realizado pocos estudios comparativos. Objetivo: Comparar y analizar la prevalencia de trastornos psiquiátricos en Latinoamérica. Metodología: Revisión y comparación de estudios latinoamericanos. Resultados: Estudios de tercera generación llevados a cabo sobre mues- tras de población

  7. LA TEORÍA DE LA EFICIENCIA DINÁMICA

    Microsoft Academic Search

    Jesús Huerta de Soto

    2011-01-01

    En este artículo se presenta un concepto alternativo de eficiencia económica de carácter dinámico para superar el concepto estático de origen paretiano hasta ahora dominante. Tras explicar el proceso de formación del concepto paretiano se propone reintroducir la dimensión dinámica de la eficiencia basada en la capacidad creativa y coordinadora de la función empresarial. Se estudian asimismo, las íntimas relaciones

  8. TECNOLOGÍAS ANAEROBIAS PARA LA DEPURACIÓN TERMOFÍLICA DE VERTIDOS DE DESTILERÍAS VÍNICAS

    Microsoft Academic Search

    Pérez García; Romero García

    RESUMEN: Se ha estudiado el período de reinicio, puesta en funcionamiento y operación de dos tecnologías anaerobias, Tanque Agitado (TA) y Filtro Anaerobio (FA), susceptibles de ser utilizadas para la degradación de vertidos de destilerías vínicas (vinazas de vino) en condiciones anaerobias termofílicas (55°C). Los resultados experimentales obtenidos indican que los reactores TA pueden operar tras dos años de inactividad

  9. \\

    Microsoft Academic Search

    Evguenia Fediakova

    RESUMEN Los procesos socioeconómicos y políticos de los últimos treinta años han transformado significativamente el movimiento evangélico chileno. Tras romper su marginalidad social y simbó- lico-espiritual, las iglesias evangélicas se consolidan como un nuevo protagonista de la socie- dad civil. Los imperativos de establecer una vinculación más estrecha con la sociedad y la creciente conciencia de ser una importante fuerza

  10. La dialéctica política en Andalucía. Partidos y autogobierno

    Microsoft Academic Search

    José Acosta Sánchez

    2002-01-01

    RESUMEN El objeto es investigar la relación entre el subsistema político implantado en la Comunidad Autónoma de Andalucía tras las primeras elecciones autonómicas de 1982 y el proceso de autogobierno de estos veinte años. ¿Hasta qué punto las fuerzas parlamentarias y las instituciones de la Junta han hecho efectiva la aplicación del Estatuto y se han obtenido resultados coherentes con

  11. LA GESTIÓN DEL CONOCIMIENTO PARA LA GESTIÓN DE LOS RIESGOS DE DESASTRE DESDE LA PERSPECTIVA DEL DESARROLLO LOCAL EN EL MUNICIPIO DE MOA: UN PROYECTO EN DESARROLLO

    Microsoft Academic Search

    Carmen Delia Almaguer Riverón; Allan Pierra Conde

    2009-01-01

    Las causas que subyacen tras los desastres, son muchas y variadas, ellas incluyen las condiciones meteorológicas cada vez más extremas, el aumento de la densidad de la población en los centros urbanos y la concentración de las actividades económicas en ciertas regiones. Todo esto, unido al proceso de globalización facilita la propagación de virus peligrosos, agentes contaminantes y fallas técnicas.

  12. Trash Pie: Is Your School Serving?

    NSDL National Science Digital Library

    Krista M. Hoover

    2010-03-01

    In observation of Earth Day, third-grade students were invited to examine what they contribute to the landfill and learn new ways they could help protect the environment. In this lesson, students collected, evaluated, and displayed data comparing the tras

  13. Superficies bioactivas en implantología: una nueva perspectiva

    Microsoft Academic Search

    A. Cutando; G. Gómez-Moreno; C. Arana

    2007-01-01

    RESUMEN Actualmente, tras años de investigación en implantología, en los cuales se han realizado mu- chos trabajos, en donde se han estudiado diferentes tipos de superficies de implantes, lisas y rugosas, en un intento de mejorar, tanto en el tiempo como en la calidad , la osteointegración, se ha concluido que los implantes de superficie rugosa con un intervalo de

  14. CONTROL DE LA APERTURA Y CIERRE DE LA FLOR DICÓGAMA DEL AGUACATE

    Microsoft Academic Search

    J. Cuevas; C. Cabezas

    El aguacate es dicógamo. Su flor abre primero como femenina y, tras un cierre, lo hace como masculina. Estas fases de apertura y cierre de la flor regulan la exposición ordenada de los órganos reproductivos a insectos vectores. Aunque se conocen diferentes alteraciones del ciclo, escaso es el conocimiento sobre los órganos reguladores del movimiento de los tépalos y las

  15. LA PRÁCTICA EDUCATIVA CON DISCAPACITADOS

    Microsoft Academic Search

    Eduardo Ullate Rada

    2010-01-01

    La práctica educativa con discapacitados suponía un reto para mí. Con la realización del curso de monitor de tiempo libre me vi obligado a realizar unas prácticas educativas que no sabía en qué lugar y ciudad iba a realizarlas. Tras una larga meditación decidí explorar un “nuevo mundo”, el de la educación de personas discapacitadas.

  16. TRATAMIENTOS CON ACIDO ACÉTICO DE CULTIVOS DE E. COLI Y SALMONELLA IN-VITRO Y EN LÍQUIDOS ESCURRIDOS DEL LAVADO DE CANALES DE POLLO TREATMENTS OF ACETIC ACID FOR E. COLI AND SALMONELLA IN-VITRO AND IN RUN-OFF FLUIDS FROM POULTRY WASHES

    Microsoft Academic Search

    S. M. Jiménez; M. C. Tiburzi; M. S. Salsi; M. A. Moguilevsky; M. E. Pirovani

    2008-01-01

    Studies to evaluate the in-vitro effectiveness of acetic acid against Escherichia coli and Salmonella Hadar affected by acid concentration and temperature were carried out. In a processing model system, the run-off fluids from washes of chicken carcasses experimentally contaminated with Salmonella, was also assessed. In-vitro reductions were compared with reductions predicted by models on inoculated chicken skin, as well. In-vitro

  17. Tratamento conservador da fratura toracolombar do tipo explosão: análise radiográfica da cifose pós-traumática Conservative treatment of thoracolumbar burst fractures: radiographic analysis of post-traumatic kyphosis Tratamiento conservador de la fractura toracolumbar del tipo explosión: análisis radiográfico de la cifosis postraumática

    Microsoft Academic Search

    Osmar Avanzi; Elcio Landim; Robert Meves; Maria Fernanda Silber Caffaro; Ricardo Shigueaki Umeta; Cristovam Miguel Neto

    Introduction: the post-traumatic kyphosis is a complication reported after conservative treatment of thoracolumbar burst fracture. The majority of the series evaluates all subtypes of Magerl and discuss their findings based on the average loss of kyphosis during the follow-up. Objective: evaluation of radiographic outcomes regarding kyphosis in patients with fractures subtype A3 of Magerl according to the average variation between

  18. TELEMAC : AN INTEGRATED SYSTEM TO REMOTELY MONITOR AND CONTROL ANAEROBIC WASTEWATER TREATMENT PLANTS THROUGH THE INTERNET TELEMAC: UN SISTEMA INTEGRADO PARA LA MONITORIZACION Y CONTROL DE DIGESTORES ANAEROBIOS PARA EL TRATAMIENTO DE AGUAS RESIDUALES A TRAVEZ DE INTERNET TELEMAC : UN SYSTEME INTEGRE POUR SURVEILLER ET PILOTER VIA INTERNET DES PROCEDES DE DEPOLLUTION PAR FERMENTATION ANAEROBIE

    Microsoft Academic Search

    O. Bernard; B. Chahuat; A. Hélias; B. Le Dantec; J.-P. Steyer; L. Lardon; P. Neveu

    The TELEMAC project brings new methodologies issued from the Information and Science Technologies field to the world of water treatment. TELEMAC proposes an advanced remote management system which adapts to most anaerobic wastewater treatment plants that do not benefit from a local expert in wastewater treatment. The TELEMAC system takes advantage of new sensors to automatically stabilise the treatment plant,

  19. Meat supplementation increases arm muscle area in Kenyan schoolchildren.

    PubMed

    Neumann, Charlotte G; Jiang, Luohua; Weiss, Robert E; Grillenberger, Monika; Gewa, Constance A; Siekmann, Jonathan H; Murphy, Suzanne P; Bwibo, Nimrod O

    2013-04-14

    The present study examines the effect of animal-source-food (ASF) intake on arm muscle area growth as part of a larger study examining causal links between ASF intake, growth rate, physical activity, cognitive function and micronutrient status in Kenyan schoolchildren. This randomised, controlled feeding intervention study was designed with three isoenergetic feeding interventions of meat, milk, and plain traditional vegetable stew (githeri), and a control group receiving no snack. A total of twelve elementary schools were randomly assigned to interventions, with three schools per group, and two cohorts of 518 and 392 schoolchildren were enrolled 1 year apart. Children in each cohort were given feedings at school and studied for three school terms per year over 2 years, a total of 9 months per year: cohort I from 1998 to 2000 and cohort II from 1999 to 2001. Food intake was assessed by 24 h recall every 1-2 months and biochemical analysis for micronutrient status conducted annually (in cohort I only). Anthropometric measurements included height, weight, triceps skinfold (TSF) and mid-upper-arm circumference (MUAC). Mid-upper-arm muscle area (MAMA) and mid-upper-arm fat area (MAFA) were calculated. The two cohorts were combined for analyses. The meat group showed the steepest rates of gain in MUAC and MAMA over time, and the milk group showed the next largest significant MUAC and MAMA gain compared with the plain githeri and control groups (P< 0.05). The meat group showed the least increase in TSF and MAFA of all groups. These findings have implications for increasing micronutrient intake and lean body mass in primary schoolchildren consuming vegetarian diets. PMID:22856533

  20. Far-Ultraviolet Imaging of the Hubble Deep Field North: Star Formation in Normal Galaxies at z<1

    E-print Network

    Teplitz, H I; Brown, T M; Chary, R; Colbert, J W; Conselice, C J; De Mello, D F; Dickinson, M; Ferguson, H C; Gardner, J P; Menanteau, F; Gardner, Jonathan P.

    2006-01-01

    We present far-ultraviolet (FUV) imaging of the Hubble Deep Field North (HDF-N) taken with the Solar Blind Channel of the Advanced Camera for Surveys (ACS/SBC) and the FUV MAMA detector of the Space Telescope Imaging Spectrograph (STIS) onboard the Hubble Space Telescope. The full WFPC2 deep field has been observed at 1600 Angstroms. We detect 134 galaxies and one star down to a limit of FUV_{AB} ~ 29. All sources have counterparts in the WFPC2 image. Redshifts (spectroscopic or photometric) for the detected sources are in the range 0UV vs. Beta relationship. We...

  1. Air and biological monitoring of toluene diisocyanate in a flexible foam plant.

    PubMed

    Tinnerberg, H; Dalene, M; Skarping, G

    1997-03-01

    Comparative air measurements of toluene diisocyanate (TDI) were performed in a 5.6 m3 standard atmosphere and at a TDI flexible foam plant. Air samples were collected in midget impinger flasks containing 9-(N-methyl-amino-methyl)-anthracene (MAMA) in toluene and on 13-mm glass-fiber filters impregnated with MAMA and glycerol analyzed by LC-UV and with filter-tape instruments. In the laboratory study the average amounts of the TDI-MAMA derivatives determined were higher for filters compared to impingers when tested at concentrations between 16 and 150 micrograms/m3 (n = 29). At the TDI foaming plant the amount of TDI-MAMA collected on the filters compared with impingers showed higher TDI values at low concentrations and lower values at higher concentrations. The same was seen for the filter-tape measurements, but for two samples at very low concentrations the response was much lower. The average air concentration was 29.8 micrograms/m3 (12.5-79.9; n = 12). The highest exposure peak measured was approximately 3 mg TDI/m3. 2,4- and 2,6-toluene diamine (TDA) in urine (U-TDA) and in plasma (P-TDA) from four exposed workers and one volunteer were determined after strong acid hydrolysis as their pentafluoro-propionic anhydride derivatives using gas chromatography-mass spectrometry. The ions monitored were the M-20 ions (M = molecular weight) of the TDA and trideuterium labeled TDA as the internal standard. The P-TDA among the workers varied between 1-38 micrograms/L and between 7-24 micrograms/L for 2,4- and 2,6-TDA, respectively. The individual plasma levels among the workers over the 3-day periods varied between 7-73%. For the volunteer, P-TDA reached a maximum about 24 hours after the last exposure. The half-time of P-TDA for the volunteer was about 10 days. The urine levels (U-TDA) varied greatly with time and exposure. High peaks were found during or shortly after the exposure. No clear correlation between air levels of TDI measured with the filter-tape instruments and levels of TDA in hydrolyzed urine and plasma was seen, but the U-TDAMax followed the exposure in time as measured with the filter-tape instruments. PMID:9075314

  2. Tom Ames Prayer, by Steve Earle appears on Steve Earle, "Train a Comin"

    E-print Network

    Reiners, Peter W.

    )trouble son, your (G)mama wouldn't (D)under(G)stand. (G)So he took his dad's money and his brother's old bay)quietly I beg(G)an to (D)file and (G)plot. #12;(G)They sent that old preacher down to my cell he said, "the) (Em)So he cocked both his pistols, (C)spit in the dirt, and (G)walked in(D)to that (G)street. #12;

  3. Detection and differentiation of CVI988 (Rispens vaccine) from other serotype 1 Marek's disease viruses.

    PubMed

    Gimeno, Isabel M; Dunn, John R; Cortes, Aneg L; El-Gohary, Abd El-Galil; Silva, Robert F

    2014-06-01

    The serotype 1 Marek's disease virus (MDV) is the causative agent for Marek's disease (MD), a lymphoproliferative disease of chickens of great concern to the poultry industry. CVI988 (Rispens vaccine), an attenuated serotype 1 MDV, is currently the most efficacious commercially available vaccine for preventing MD. However, it is difficult to detect and differentiate CVI988 when other serotype 1 MDVs are present. To facilitate the detection of CVI988, we developed two sets of primers for a mismatch amplification mutation assay (MAMA) PCR that targeted the single nulceotide polymorphism associated with the H19 epitope of the phosphorylated protein 38 gene. The PCR was very specific. One primer set (oncogenic primers) amplified DNA from 15 different serotype 1 MDVs except CVI988. The other primer set (CVI988 primers) amplified DNA from CVI988 but not from any of the other 15 serotype 1 MDVs. A real-time PCR assay was developed using MAMA primers, and specificity and sensitivity was evaluated in vitro and in vivo. Mixtures of plasmids (CVI988 plasmid and oncogenic plasmid) at various concentrations were used to evaluate the sensitivity/specificity of MAMA primers in vitro. Both primer setswere able to amplify as little as one copy of their respective plasmid. Oncogenic primers were highly specific and only amplified CVI988 plasmid when the concentration of oncogenic plasmid was very low (1 X 10(1)) and CVI988 plasmid was very high (1 X 10(6)). Specificity of CVI988 primers was not as high because they could amplify oncogenic plasmids when the concentration of CVI988 plasmid was 1 x 10(3) and the concentration of oncogenic 1 x 10(2). Validation of MAMA primers in in vivo samples demonstrated that oncogenic primers can be used for both early diagnosis of MD in feather pulp (FP) samples collected at 3 wk of age and confirmation of MD diagnosis in tumors. CVI988 primers could be used to monitor CVI988 vaccination in samples with a low load of oncogenic MDV DNA (latently infected samples or negative) but not in samples with a high load of oncogenic MDV DNA (tumors). Our results suggest that monitoring CVI988 vaccination in FP samples collected at 1 wk of age ensures the specificity of the CVI988 primers. PMID:25055627

  4. From EROS to DUO, ALADIN, GATT and others: wide-field astronomy.

    NASA Astrophysics Data System (ADS)

    Guibert, J.

    1997-12-01

    This report illustrates the major role of large-field imaging in all the domains of astrophysics, and presents some recent results. Most of these are based on digitisation and analysis of Schmidt images taken in the course of either sky surveys or specific programmes. Special emphasis is put on the crucial importance of computer storage and processing capabilities, as well as efficient analysis and calibration software, for images up to 2 gigabytes. The resources of the Image Analysis Centre of the Observatoire de Paris, including the MAMA facility, used by a wide national and international community of astronomers, will be briefly presented.

  5. Función neuropsicológica en la fenilcetonuria tratada precozmente: Una revisión

    Microsoft Academic Search

    Louise H. Crossley; Peter J. Anderson

    2010-01-01

    ResumenLa fenilcetonuria (FCU) es un error metabólico congénito que implica una deficiencia de la enzima fenilalanina hidroxilasa. Este proceso da lugar a niveles elevados de fenilalanina y niveles bajos de tirosina. Si no se administra tratamiento aparecen graves secuelas neuropatológicas y neuroconductuales. La puesta en práctica de la detección sistemática de recién nacidos y el tratamiento dietético precoz ha reducido

  6. El estudio NCI-MATCH vinculará medicamentos dirigidos para el cáncer con anomalías genéticas

    Cancer.gov

    Los investigadores del estudio a nivel nacional NCI-MATCH: Análisis molecular para la elección de tratamientos, anunciaron que el estudio busca determinar la eficacia de los tratamientos dirigidos en personas con tumores que presentan mutaciones genéticas específicas independientemente de su tipo de cáncer.

  7. Changes in the structure and composition of two Pinus nigra subsp. salzmannii forests over a century of different

    E-print Network

    Herrera, Carlos M.

    Changes in the structure and composition of two Pinus nigra subsp. salzmannii forests over ordenados de Pinus nigra subsp. salzmannii durante un siglo de tratamientos selvícolas diferentes Los tratamientos sel- vícolas favorecieron a Pinus nigra y no beneficiaron a otras especies. La cantidad de árboles

  8. On-Site Wastewater Treatment Systems: Operation and Maintenance (Spanish) 

    E-print Network

    Lesikar, Bruce J.; Enciso, Juan

    2000-08-15

    aguas subterr?neas. Los sistemas individuales para el tratamiento de aguas negras se pueden conseguir de muchos tipos y en muchos tama?os. Los requisitos del mantenimiento y la operaci?n de cada uno dependen de: 3 El m?todo de tratamiento utilizado para...

  9. Laboratori de Conducta i Sistemes Dinmics (LabCSD) El Laboratori de Conducta i Sistemes Dinmics (LabCSD) sorgeix de la collaboraci

    E-print Network

    Oro, Daniel

    del neurofeedback en el tratamiento del trastorno por déficit de atención e hiperactividad frente tratamiento del trastorno de ansiedad social (PSI2010-17563) · El estudio del Sluggish Cognitive Tempo (SCT) en un diseño longitudinal para mejorar la conceptualización del trastorno por déficit de atención e

  10. Los estudios clnicos y la medicina complementaria y alternativa

    E-print Network

    Baker, Chris I.

    enfermedades y trastornos. La participación en los estudios clínicos tiene riesgos y beneficios. El gobierno atención sanitaria y contribuye a la comprensión de las enfermedades y los trastornos (por ejemplo, la: Estudios sobre tratamientos someten a prueba los tratamientos para una determinada enfermedad o trastorno

  11. Detection and treatment of transplant renal artery stenosis

    PubMed Central

    Krishnamoorthy, Sriram; Gopalakrishnan, Ganesan; Kekre, Nitin Sudhakar; Chacko, Ninan; Keshava, Shyam; John, George

    2009-01-01

    Purpose: To assess the effects of transplant renal artery stenosis (TRAS) on blood pressure, renal function, and graft survival. To assess the usefulness of Doppler in predicting the clinical significance of TRAS and also to identify the predictive factors in Doppler that correlated with clinical features of TRAS. Materials and Methods: A prospective study was done on consecutive renal allograft recipients at Christian Medical College, over a period of 66 months from January 2002. All recipients underwent Doppler ultrasound (DUS) evaluation on the fifth post-operative day. Subsequent evaluation was done if the patients had any clinical or biochemical suspicion of TRAS. Angiogram was done in case of a high index of suspicion of significant stenosis or before angioplasty and stenting. The clinical and radiological outcomes of the patients with symptomatic or asymptomatic TRAS were analyzed. Results: Five hundred and forty three consecutive renal allograft recipients were analyzed, of whom, 43 were found to have TRAS. Nine recipients (21%) were detected to have TRAS on first evaluation. All had a high peak systolic velocities (PSV) recorded while 25 of them had other associated features. Patients with only high PSV required no further intervention and were followed up. They had a pretransplant mean arterial pressure (MAP) of 107.83 mmHg (SD = 13.32), ranging from 90 to 133 mm Hg and a posttransplant MAP of 106.56 mmHg (SD =16.51), ranging from 83 to 150 mm Hg. Their mean nadir serum creatinine was 1.16 mg% (SD = 0.24), at detection was 1.6 mg% (SD = 1.84) and at 6 months follow-up was 1.26 mg% (SD=0.52). Of the remaining 25 patients with other associated Doppler abnormalities, 11 required further intervention in the form of re-exploration in 2, angioplasty in 3 and stenting in 6 patients. One patient in the group of patients intervened, expired in the immediate post-operative period due to overwhelming urosepsis and consumption coagulopathy. The mean creatinine clearance (Cockroft-Gault method) in this group of remaining 10 patients, before and after intervention was 44.75 ml/min (SD=17.85) and 68.96 ml/min (SD = 10.56), respectively, with a mean increase by 24.21 ml/min (P=0.000). The mean arterial pressure before and after intervention in this group were 132.80 mm Hg (SD = 13.22) and 102 mm Hg (SD = 10.55), with a decline in the MAP by 30.80 mmHg (P=0.017). The haemoglobin levels also increased from 11.72 (SD=2.13) to 12.48 gm% (SD = 1.75), with a mean increase by 0.76 gm% (P=0.05). Conclusions: Patients with isolated high PSV do not have a significant alteration of blood pressure or allograft function and required no intervention. Although high PSV with associated Doppler anomalies are more suggestive of significant TRAS, the decision regarding surgical intervention is largely based on clinical assessment. PMID:19468430

  12. [Cytogenetics and application in domesticated silkworm Bombyx mori].

    PubMed

    Li, Wei; Ge, Fang-Lan; Ye, De-Ping; Lei, Jia-Hong; Huang, Min

    2006-09-01

    Chromosome identification and karyotype analyses of Bombyx mori (Lepidoptera) have long been hampered by the high number and the absence of suitable markers, such as centromeric position and chromosome bands. Recently, the cytological map has been constructed using comparative genomic hybridization-genomic in situ hybridization and BAC-based fluorescence in situ hybridization. Dense cytogenetic maps are being constructed by integrating cytological map with molecular linkage maps. Molecular and cytogenetics will help us to reveal the structure and function of chromosome of Bombyx mori, the W chromosome is composed largely of dense nested retrotransposons, and telomeres are consist of the TTAGG motifs and two type of telomere-specific non-LTR retrotransposons (TRAS1 and SART1), the TRAS1 and SART1 with abundant transcription activity may be involved in the stabilization of chromosomal ends. PMID:16963430

  13. Cell--cell interactions in conjugating Escherichia coli: role of traT protein in surface exclusion.

    PubMed Central

    Achtman, M; Kennedy, N; Skurray, R

    1977-01-01

    Escherichia coli cells carrying the F sex factor are poor recipients in conjugation. This phenomenon is called surface exclusion. Two F cistrons, traS and traT, are independently responsible for part of the whole mechanism. The traS gene product reduces DNA transfer within stable mating aggregates. The traT gene product, pTraT, results in a greatly reduced ability to form stable mating aggregates, and thus also leads to reduced DNA transfer within the cell population. pTraT is a 25,000-dalton protein incorporated into the cell envelope outer membrane. It is found in 29,000-84,000 copies per cell, depending on the plasmid expressing it. There is a parallel variation in recipient ability. Models for surface exclusion are discussed. Images PMID:337311

  14. Asiddhatva Principle in Computational Model of A???dhy?y?

    NASA Astrophysics Data System (ADS)

    Subbanna, Sridhar; Varakhedi, Shrinivasa

    P??ini's A???dhy?y? can be thought of as an automaton to generate Sanskrit words and sentences. A???dhy?y? consists of s?tras that are organized in a systematic manner. The words are derived from the roots and affixes by the application of these s?tras that follow a well defined procedure. Therefore, A???dhy?y? is best suited for computational modeling. A computational model with conflict resolution techniques was discussed by us (Sridhar et al, 2009)[12]. In continuation with that, this paper presents, an improvised computational model of A???dhy?y?. This model is further developed based on the principle of asiddhatva. A new mathematical technique called 'filter' is introduced to comprehensively envisage all usages of asiddhatva in A???dhy?y?.

  15. Trastuzumab after Adjuvant Chemotherapy in HER2Positive Breast Cancer

    Microsoft Academic Search

    Martine J. Piccart-Gebhart; Marion Procter; Brian Leyland-Jones; Aron Goldhirsch; Michael Untch; Ian Smith; Luca Gianni; Jose Baselga; Richard Bell; Christian Jackisch; David Cameron; Mitch Dowsett; Carlos H. Barrios; Günther Steger; Chiun-Shen Huang; Michael Andersson; Moshe Inbar; Mikhail Lichinitser; István Láng; Ulrike Nitz; Hiroji Iwata; Christoph Thomssen; Caroline Lohrisch; Thomas M. Suter; Josef Rüschoff; Tamás Süto ý; Victoria Greatorex; Carol Ward; Eleanor McFadden; M. Stella Dolci; Richard D. Gelber

    2010-01-01

    background Trastuzumab, a recombinant monoclonal antibody against HER2, has clinical activity in advanced breast cancer that overexpresses HER2. We investigated its efficacy and safety after excision of early-stage breast cancer and completion of chemotherapy. methods This international, multicenter, randomized trial compared one or two years of tras- tuzumab given every three weeks with observation in patients with HER2-positive and either

  16. El teatro cubano de los 80: Creación versus oficialidad

    E-print Network

    Correa, Armando

    1992-04-01

    gesticula un discurso. Tras él cuelga la bandera soviética. Delante de la tribuna leninista Los Beatles interpretan, en una plataforma, su canción Revolution. Globos terráqueos flotan sobre ellos. Entres los globos terráqueos Marilyn Monroe desciende... por un tubo, para bailar en otra plataforma. . . . Delante de la plataforma de Marilyn, Charles Chaplin hace bailar dos panecillos sobre una mesa. Marilyn sonsaca a Chaplin. Chaplin baila en patines con John Lennon. Marilyn se come un panecillo y...

  17. Explorando el papel del intercambio virtual en el desarrollo de la competencia translingüística y transcultural

    E-print Network

    Rossomondo, Amy E.; Alonso, Maria

    2009-09-01

    viabilidad de implementar los intercambios virtuales en instituciones de recursos limitados y posibles alternativas para cursos y programas de nivel b&sico. Key Words: aprendizaje intercultural, competencia transcultural, competencia translingiiistica, espa... (UX) en colaboracion con profesorado de la Universidad de Costa Rica (UCR). Tras definir y esbozar los objetivos del proyecto en base a teorias actuales sobre el papel del aprendizaje de cultura dentro de la clase de lengua extranjera, este estudio...

  18. A 64Mb DRAM with meshed power line

    Microsoft Academic Search

    T. Yamada; Y. Nakata; J. Hasegawa; N. Amano; A. Shibayama; M. Sasago; N. Matsuo; T. Yabu; S. Matsumoto; S. Okada; M. Inoue

    1991-01-01

    A 64-Mb dynamic RAM (DRAM) has been developed with a meshed power line (MPL) and a quasi-distributed sense-amplifier driver (qDSAD) scheme. It realizes high speed, tRAS=50 ns (typical) at Vcc=3.3 V, and 16-b input\\/output (I\\/O). This MPL+qDSAD scheme can reduce sensing delay caused by the metal layer resistance. Furthermore, to suppress crosstalk noise, a VSS shield peripheral layout scheme has

  19. Functional heterogeneity of the red-cockaded woodpecker habitat in the Sam Houston National Forest: a geographic information system approach 

    E-print Network

    Azevedo, Joao Carlos Martins De

    1995-01-01

    Forest A Geographic Information System Approach. (December 1995) Joao Carlos Martins de Azevedo, B. S. , Universidade de Tras-os-Montes e Alto Douro, Portugal Chair of Advisory Committee: Dr. Steven B. Jack Red-cockaded woodpecker (RCW) populations... 3 Forest Type Distribution in the Raven District. 4 Distribution of Active and Inactive Colonies in the Raven District 35 5 Habitat Suitability Map for Approach 1, 6 Habitat Suitability Map for Approach 2. . . . 7 Habitat Suitability Map...

  20. Altered Expression of Autoimmune Regulator in Infant Down Syndrome Thymus, a Possible Contributor to an Autoimmune Phenotype

    PubMed Central

    Lundberg, Vanja; Lindgren, Susanne; Gudmundsdottir, Judith; Sandström, Kerstin; Kämpe, Olle; Annerén, Göran; Gustafsson, Jan; Sunnegårdh, Jan; van der Post, Sjoerd; Telemo, Esbjörn; Berglund, Martin; Ekwall, Olov

    2014-01-01

    Down syndrome (DS), caused by trisomy of chromosome 21, is associated with immunological dysfunctions such as increased frequency of infections and autoimmune diseases. Patients with DS share clinical features, such as autoimmune manifestations and specific autoantibodies, with patients affected by autoimmune polyendocrine syndrome type 1. Autoimmune polyendocrine syndrome type 1 is caused by mutations in the autoimmune regulator (AIRE) gene, located on chromosome 21, which regulates the expression of tissue-restricted Ags (TRAs) in thymic epithelial cells. We investigated the expression of AIRE and TRAs in DS and control thymic tissue using quantitative PCR. AIRE mRNA levels were elevated in thymic tissue from DS patients, and trends toward increased expression of the AIRE-controlled genes INSULIN and CHRNA1 were found. Immunohistochemical stainings showed altered cell composition and architecture of the thymic medulla in DS individuals with increased frequencies of AIRE-positive medullary epithelial cells and CD11c-positive dendritic cells as well as enlarged Hassall’s corpuscles. In addition, we evaluated the proteomic profile of thymic exosomes in DS individuals and controls. DS exosomes carried a broader protein pool and also a larger pool of unique TRAs compared with control exosomes. In conclusion, the increased AIRE gene dose in DS could contribute to an autoimmune phenotype through multiple AIRE-mediated effects on homeostasis and function of thymic epithelial cells that affect thymic selection processes. PMID:25038256

  1. Scattered light in the STIS echelle modes

    NASA Technical Reports Server (NTRS)

    Landsman, W.; Bowers, C.

    1997-01-01

    The Space Telescope Imaging Spectrograph (STIS) echelle spectra obtained during the Early Release Observations have non-zero residuals in the cores of saturated interstellar lines, indicating the need for a scattered light correction. A rough measure of the magnitude of the needed correction shows the ratio of the interorder to the in-order flux in different echelle modes in both pre-launch calibration images of a continuum lamp source and in post-launch images of stellar continuum sources. The interorder and in-order fluxes are computed by averaging the central 200 pixels in the dispersion direction. The amount of scattered light in the interorder region rises toward shorter wavelengths for two reasons: (1) the order separation decreases toward shorter wavelengths; and (2) the amount of echelle scattering is expected to have an inverse dependence on wavelength. At the shortest wavelengths the fraction of light scattered into the interorder region can be 10% for the Near-ultraviolet-Multi-Anode Microchannel Array (NUV-MAMA) and 15% for the Far-ultraviolet-Multi-Anode Microchannel Array (FUV-MAMA).

  2. Minimum audible movement angle: marking the end points of the path traveled by a moving sound source.

    PubMed

    Perrott, D R; Marlborough, K

    1989-04-01

    Four experienced subjects were tested on their ability to discriminate the direction of motion or the order of events in a single-interval, two-alternative, forced-choice adaptive paradigm. Two conditions, employing a broadband "pink" noise (500-8000 Hz), were examined: (1) A continuous noise was available from the moving sound source during the entire period of travel; and (2) 10-ms noise pulses were presented from the moving source at the beginning and end of the arc traveled (during the interpulse interval the source was inactive). Minimum audible movement angle (MAMA) thresholds were significantly lower when the moving source was active throughout the period of travel (0.914 degrees) than when only the end points of the arc of travel were "marked" (1.604 degrees). These results do not support the notion that the discrimination of motion can be reduced to a simple comparison of the location of the source at signal onset and the position of the source at signal offset. The MAMA thresholds obtained with broadband noise in the current experiment are considerably lower than the thresholds previously observed with tonal targets. PMID:2708691

  3. Analysis of masked mutations in familial adenomatous polyposis

    PubMed Central

    Laken, Steven J.; Papadopoulos, Nickolas; Petersen, Gloria M.; Gruber, Stephen B.; Hamilton, Stanley R.; Giardiello, Francis M.; Brensinger, Jill D.; Vogelstein, Bert; Kinzler, Kenneth W.

    1999-01-01

    Familial adenomatous polyposis (FAP) is an autosomal-dominant disease characterized by the development of hundreds of adenomatous polyps of the colorectum. Approximately 80% of FAP patients can be shown to have truncating mutations of the APC gene. To determine the cause of FAP in the other 20% of patients, MAMA (monoallelic mutation analysis) was used to independently examine the status of each of the two APC alleles. Seven of nine patients analyzed were found to have significantly reduced expression from one of their two alleles whereas two patients were found to have full-length expression from both alleles. We conclude that more than 95% of patients with FAP have inactivating mutations in APC and that a combination of MAMA and standard genetic tests will identify APC abnormalities in the vast majority of such patients. That no APC expression from the mutant allele is found in some FAP patients argues strongly against the requirement for dominant negative effects of APC mutations. The results also suggest that there may be at least one additional gene, besides APC, that can give rise to FAP. PMID:10051640

  4. Proper motions of pre-main sequence stars { } in southern star-forming regions

    NASA Astrophysics Data System (ADS)

    Teixeira, R.; Ducourant, C.; Sartori, M. J.; Camargo, J. I. B.; Périé, J. P.; Lépine, J. R. D.; Benevides-Soares, P.

    2000-09-01

    We present proper motion measurements of pre-main sequence (PMS) stars associated with major star-forming regions of the southern hemisphere (Chamaeleon, Lupus, Upper Scorpius - Ophiuchus, Corona Australis), situated in the galactic longitude range l = 290degr to l = 360degr . A list of PMS stars as complete as possible was established based on the Herbig and Bell catalogue and many new catalogues like the PDS survey, the catalogue of Herbig Ae/Be stars by Thé et al. (\\cite{the}), X-rays surveys, etc. The measurements made use of public material (mainly AC2000 and USNO-A2.0 catalogues) as well as scans of SERC-J Schmidt plates with the MAMA measuring machine (Paris) and Valinhos CCD meridian circle observations (Brazil). We derived proper motions for 213 stars, with an accuracy of 5 to 10 mas/yr depending mainly on the difference of epochs between the position sources. The main characteristics of the sample are discussed. We show that systematic motions of groups of stars exist, which are not explained by the reflex solar motion. Based on observations made at Valinhos CCD Meridian Circle. Based on measurements made with MAMA automatic measuring machine. Table 4 is only available in electronic form at the CDS via anonymous ftp to cdsarc.u-strasbg.fr (130.79.128.5) or via http://cdsweb.u-strasbg.fr/Abstract.html

  5. Surgical Repair of Transplant Renal Artery Stenosis With Preserved Cadaveric Iliac Artery Grafts

    PubMed Central

    Shames, Brian D.; Odorico, Jon S.; D’Alessandro, Anthony M.; Pirsch, John D.; Sollinger, Hans W.

    2003-01-01

    Objective To review the authors’ experience with ABO-matched, preserved, cadaveric, iliac artery grafts for treatment of transplant renal artery stenosis (TRAS). Summary Background Data TRAS is an important and treatable cause of hypertension and graft dysfunction in renal allograft recipients. Surgical treatment is reserved for lesions that are not amenable to percutaneous transluminal angioplasty (PTA) or for recurrence after PTA. Various surgical options for reconstruction of the transplant renal artery exist, although no single technique has been demonstrated to be superior. The authors have used preserved, blood type-matched, iliac artery grafts procured from cadaver organ donors to reconstruct transplant renal arteries in patients with specific lesions and following unsuccessful PTAs. Methods Between 1991 and 2001, 21 patients underwent reconstruction of allograft renal arteries using cadaveric iliac artery as conduit. Charts, operative notes, and imaging studies of all patients were reviewed. A successful intervention for TRAS was defined as technical success as well as a decrease in serum creatinine and/or blood pressure 6 weeks after the procedure. Development of a hemodynamically significant lesion following renal artery reconstruction was considered a recurrence. Results In patients treated with surgical reconstruction, hemodynamically significant TRAS occurred at or within 1 to 2 mm of the anastomosis in 13 patients, in the middle of the renal artery in 4, and secondary to a kink in 2 patients. Surgical treatment was undertaken in seven patients following unsuccessful PTA. Two patients had aneurysms of the iliac artery. Reconstruction using cadaveric iliac artery was successful in 19 of 21 (90%) patients, and only 1 these patients (4.8%) failed due to recurrence, with a median follow-up of 42 months. Graft loss secondary to TRAS occurred in two patients. The authors have not seen any long-term complications related to cadaveric iliac artery grafts, and the majority of the allografts continue to function well. Conclusions Surgical reconstruction of the transplant renal artery with blood type-matched iliac artery grafts should be considered a viable option for patients with specific anatomic lesions, those who have had an unsuccessful PTA, and those with recurrence following PTA. PMID:12496538

  6. [First mexican consensus on recommendations of the multidisciplinary care of patients with glioblastoma multiforme (GBM): Mexican Interdisciplinary Group on Neuro-Oncology Research (GIMINO)].

    PubMed

    Celis, Miguel Ángel; Alegría-Loyola, Marco Antonio; González-Aguilar, Alberto; Martínez-Tlahuel, Jorge; Green-Renner, Dan; Reyes-Soto, Gervith; Arellano-Reynoso, Alfonso; Flores-Castro, Jesús Manuel; Moreno-Jiménez, Sergio; Poitevin-Chacón, María Adela; Cacho-Díaz, Bernardo; Olvera-Manzanilla, Eduardo; Díaz-Victoria, Ana Ruth; Aguilar-Castañeda, Erika; Granados-García, Martín; Rodríguez-Orozco, Josana; Herrera-Goepfert, Roberto; Álvarez-Avitia, Miguel Ángel

    2015-01-01

    El GBM es uno de los tumores más agresivos y con peor pronóstico del sistema nervioso central. Los tratamientos aplicados hasta el momento han logrado aumentar sensiblemente la supervivencia de estos pacientes, dependiendo de la edad, el estado cognitivo y la autonomía de los propios individuos. En función de estos parámetros se realiza tanto el tratamiento inicial como en la recurrencia, así como el seguimiento de la enfermedad mediante estudios de imagen. Una vez que el paciente entra en fase terminal y se suspenden los tratamientos curativos, se ha de garantizar el respeto a la voluntad anticipada y el desarrollo y aplicación de las terapias paliativas. PMID:26089278

  7. Leucemia–para profesionales de salud

    Cancer.gov

    Información del Instituto Nacional del Cáncer para profesionales de salud sobre el tratamiento de la leucemia, así como referencias a estudios clínicos, investigación, estadísticas y otros temas relacionados con este tipo de cáncer.

  8. Neoplasias de células plasmáticas (incluso mieloma múltiple)–para profesionales de salud

    Cancer.gov

    Información del Instituto Nacional del Cáncer para profesionales de salud sobre el tratamiento del mieloma múltiple y otras neoplasias de células plasmáticas, así como referencias a estudios clínicos, investigación, estadísticas y otros temas relacionados.

  9. Tumores cerebrales–para profesionales de salud

    Cancer.gov

    Información del Instituto Nacional del Cáncer para profesionales de salud sobre el tratamiento de los tumores cerebrales, así como referencias a estudios clínicos, estadísticas y otros temas relacionados con estos tipos de cáncer.

  10. Neoplasias de células plasmáticas (incluso mieloma múltiple)

    Cancer.gov

    Información del Instituto Nacional del Cáncer sobre el tratamiento del mieloma múltiple y otras neoplasias de células plasmáticas, así como referencias a estudios clínicos, investigación, estadísticas y otros temas relacionados.

  11. Leucemia

    Cancer.gov

    Información del Instituto Nacional del Cáncer sobre el tratamiento de la leucemia, así como referencias a estudios clínicos, investigación, estadísticas y otros temas relacionados con este tipo de cáncer.

  12. Cáncer de ovario, de trompa de Falopio y primario de peritoneo–para profesionales de salud

    Cancer.gov

    Información del Instituto Nacional del Cáncer para profesionales de salud sobre el tratamiento, la prevención, la genética, las causas y los exámenes de detección del cáncer de ovario, así como referencias a estudios clínicos, investigación, estadísticas y otros temas relacionados.

  13. Cáncer de páncreas–para profesionales de salud

    Cancer.gov

    Información del Instituto Nacional del Cáncer para profesionales de salud sobre el tratamiento del cáncer de páncreas, así como referencias a estudios clínicos, investigación y otros temas relacionados con este tipo de cáncer.

  14. Lo que usted necesita saber sobre™ el cáncer de cérvix

    Cancer.gov

    Contiene información sobre las opciones de tratamiento, la obtención de una segunda opinión, los cuidados de seguimiento y las fuentes de apoyo para alguien que ha sido diagnosticado recientemente con cáncer de cérvix o cuello uterino.

  15. Cáncer de riñón –para profesionales de salud

    Cancer.gov

    Información del Instituto Nacional del Cáncer para profesionales de salud sobre el tratamiento del cáncer de riñón, así como referencias a estudios clínicos, investigación, estadísticas y otros temas relacionados con este tipo de cáncer.

  16. Tumores extracraneales de células germinativas–para profesionales de salud

    Cancer.gov

    Información del Instituto Nacional del Cáncer para profesionales de salud sobre el tratamiento del tumor extracraneal de células germinativas en los niños, así como referencias a estudios clínicos y otros temas relacionados.

  17. Cáncer de pulmón–para profesionales de salud

    Cancer.gov

    Información del Instituto Nacional del Cáncer para profesionales de salud sobre el tratamiento, la prevención, las causas y los exámenes de detección del cáncer de pulmón, así como referencias a estudios clínicos, investigación, estadísticas y otros temas relacionados.

  18. Tumores cerebrales

    Cancer.gov

    Información del Instituto Nacional del Cáncer sobre el tratamiento de los tumores cerebrales, así como referencias a estudios clínicos, estadísticas y otros temas relacionados con estos tipos de cáncer.

  19. Cáncer de cuello uterino–para profesionales de salud

    Cancer.gov

    Información del Instituto Nacional del Cáncer para profesionales de salud sobre el tratamiento, la prevención, las causas y los exámenes de detección del cáncer de cuello uterino, así como referencias a estudios clínicos, investigación, estadísticas y otros temas relacionados.

  20. Cáncer de cabeza y cuello–para profesionales de salud

    Cancer.gov

    Información del Instituto Nacional del Cáncer para profesionales de salud sobre el tratamiento, la prevención, las causas y los exámenes de detección de los cánceres de cabeza y cuello, así como referencias a estudios clínicos, investigaciones, estadísticas y temas relacionados.

  1. Tensión postraumática relacionada con el cáncer (PDQ®)

    Cancer.gov

    Resumen de información revisada por expertos acerca de la tensión postraumática y síntomas relacionados en los pacientes con cáncer, sobrevivientes del cáncer y miembros de la familia. Se discuten la evaluación y tratamiento de estos síntomas.

  2. Aspectos relacionados con la sexualidad y la reproducción –para profesionales de salud (PDQ®)

    Cancer.gov

    Resumen de información revisada por expertos acerca de los factores que pueden afectar el funcionamiento sexual de las personas con cáncer. Se discuten además temas sobre la fecundidad relacionados con el tratamiento del cáncer.

  3. Ttulos Propios de la UAM (curso acadmico 2007 / 2008) TTULOS PROPIOS DE LA UAM

    E-print Network

    Autonoma de Madrid, Universidad

    Fisioterapia Respiratoria Diploma de Formación Superior en Cuidados Paliativos y Tratamiento del Soporte del Paciente con Cáncer #12;TÍTULOS PROPIOS DE LA UAM D.F.S en Fisioterapia Osteoarticular D.F.S en

  4. Cáncer de la corteza suprarrenal

    Cancer.gov

    Información del Instituto Nacional del Cáncer sobre el tratamiento del carcinoma de corteza suprarrenal, así como referencias a estudios clínicos, investigación y otros temas relacionados con este tipo de cáncer.

  5. Cáncer de riñón

    Cancer.gov

    Información del Instituto Nacional del Cáncer sobre el tratamiento del cáncer de riñón, así como referencias a estudios clínicos, investigación, estadísticas y otros temas relacionados con este tipo de cáncer.

  6. Cáncer de útero

    Cancer.gov

    Información del Instituto Nacional del Cáncer sobre el tratamiento, la prevención, las causas y los exámenes de detección del cáncer uterino, así como referencias a estudios clínicos, investigación, estadísticas y otros temas relacionados.

  7. Cáncer de intestino delgado

    Cancer.gov

    Información del Instituto Nacional del Cáncer sobre el tratamiento del cáncer de intestino delgado, así como referencias a estudios clínicos, investigación y otros temas relacionados con este tipo de cáncer.

  8. Cáncer de hígado y de conducto biliar

    Cancer.gov

    Información del NCI sobre el tratamiento, la prevención y los exámenes de detección del cáncer de hígado y de conducto biliar, así como referencias a estudios clínicos, investigación y otros temas relacionados con este tipo de cancer.

  9. Cáncer de vejiga

    Cancer.gov

    Información del Instituto Nacional del Cáncer sobre el tratamiento, las causas y los exámenes de detección del cáncer de vejiga, así como referencias a estudios clínicos, investigación, estadísticas y otros temas relacionados con este tipo de cáncer.

  10. Cáncer de próstata

    Cancer.gov

    Información del Instituto Nacional del Cáncer sobre el tratamiento, la prevención, las causas y los exámenes de detección del cáncer de próstata, así como referencias a estudios clínicos, investigación, estadísticas y otros temas relacionados.

  11. Cáncer de vesícula biliar

    Cancer.gov

    Información del Instituto Nacional del Cáncer sobre el tratamiento del cáncer de vesícula biliar, así como referencias a estudios clínicos, investigación y otros temas relacionados con este tipo de cáncer.

  12. Cáncer de estómago

    Cancer.gov

    Información del Instituto Nacional del Cáncer sobre el tratamiento, la prevención, las causas y los exámenes de detección del cáncer de estómago (gástrico), así como referencias a estudios clínicos, investigación, estadísticas y otros temas relacionados.

  13. Cáncer de cuello uterino

    Cancer.gov

    Información del Instituto Nacional del Cáncer sobre el tratamiento, la prevención, las causas y los exámenes de detección del cáncer de cuello uterino, así como referencias a estudios clínicos, investigación, estadísticas y otros temas relacionados.

  14. Cáncer de testículo

    Cancer.gov

    Información del Instituto Nacional del Cáncer sobre el tratamiento, las causas y los exámenes de detección del cáncer de testículo, así como referencias a estudios clínicos, investigación y otros temas relacionados con este tipo de cáncer.

  15. Cáncer de ovario, de trompa de Falopio y primario de peritoneo

    Cancer.gov

    Información del Instituto Nacional del Cáncer sobre el tratamiento, la prevención, la genética, las causas y los exámenes de detección del cáncer de ovario, así como referencias a estudios clínicos, investigación, estadísticas y otros temas relacionados.

  16. Cáncer de esófago

    Cancer.gov

    Información del Instituto Nacional del Cáncer sobre el tratamiento, la prevención y los exámenes de detección del cáncer de esófago, así como referencias a estudios clínicos, investigación, estadísticas y otros temas relacionados con este tipo de cáncer.

  17. Cáncer colorrectal

    Cancer.gov

    Información del Instituto Nacional del Cáncer sobre el tratamiento, la prevención, las causas y los exámenes de detección del cáncer de colon y recto, así como referencias a estudios clínicos, estadísticas y otros temas relacionados.

  18. Cáncer de pulmón

    Cancer.gov

    Información del Instituto Nacional del Cáncer sobre el tratamiento, la prevención, las causas y los exámenes de detección del cáncer de pulmón, así como referencias a estudios clínicos, investigación, estadísticas y otros temas relacionados.

  19. Cáncer de cabeza y cuello

    Cancer.gov

    Información del Instituto Nacional del Cáncer sobre el tratamiento, la prevención, las causas y los exámenes de detección de los cánceres de cabeza y cuello, así como referencias a estudios clínicos, investigaciones, estadísticas y temas relacionados.

  20. Cáncer de paratiroides

    Cancer.gov

    Información del Instituto Nacional del Cáncer sobre el tratamiento del cáncer de paratiroides, así como referencias a estudios clínicos, investigación y otros temas relacionados con este tipo de cáncer.

  1. Linfedema–para profesionales de salud (PDQ®)

    Cancer.gov

    Resumen de información revisada por expertos sobre la anatomía, la patofisiología, las manifestaciones clínicas, el diagnóstico y el tratamiento del linfedema relacionado con el cáncer, una afección en la que se acumula líquido linfático en los tejidos y causa inflamación..

  2. Delirio (PDQ®)

    Cancer.gov

    Resumen de información revisada por expertos acerca del delirio como una complicación del cáncer o su tratamiento. Se tratan enfoques de los cuidados médicos de apoyo y los abordajes farmacológicos para el manejo del delirio.

  3. Fatiga–para profesionales de salud (PDQ®)

    Cancer.gov

    Resumen de información revisada por expertos acerca de la fatiga, una afección caracterizada por extremo cansancio e incapacidad para funcionar por la falta de energía, que a menudo se observa como una complicación del cáncer y su tratamiento.

  4. Delirio –para profesionales de salud (PDQ®)

    Cancer.gov

    Resumen de información revisada por expertos acerca del delirio como una complicación a causa del cáncer o su tratamiento. Se discuten los enfoques de los cuidados médicos de apoyo, asi como farmacológicos para el manejo del delirio.

  5. Complicaciones gastrointestinales–para profesionales de salud (PDQ®)

    Cancer.gov

    Resumen de información revisada por expertos acerca del estreñimiento, la retención fecal, la obstrucción intestinal y la diarrea como complicaciones del cáncer o su tratamiento. Se discute el manejo de estos problemas.

  6. Náuseas y vómitos –para profesionales de salud (PDQ®)

    Cancer.gov

    Resumen de información revisada por expertos acerca de las náuseas y los vómitos como complicaciones a causa del cáncer o su tratamiento. Se discuten enfoques sobre el manejo de las náuseas y los vómitos.

  7. Memorias del Cuarto Simposio Internacional Sobre Polticas, Planificacin y Economa de los Incendios Forestales: Cambio Climtico e Incendios Forestales

    E-print Network

    Standiford, Richard B.

    Palabras clave: toma de decisiones, FARSITE, simulación de propagación del fuego, tratamientos de a menudo difícil, si no imposible. Así, muchas decisiones costosas de planificación de incendios se basan

  8. Tensión postraumática relacionada con el cáncer–para profesionales de salud (PDQ®)

    Cancer.gov

    Resumen de información revisada por expertos acerca de la tensión postraumática y síntomas relacionados en los pacientes con cáncer, sobrevivientes del cáncer y miembros de la familia. Se discuten la evaluación y tratamiento de estos síntomas.

  9. Cáncer de próstata–para profesionales de salud

    Cancer.gov

    Información del Instituto Nacional del Cáncer para profesionales de salud sobre el tratamiento, la prevención, las causas y los exámenes de detección del cáncer de próstata, así como referencias a estudios clínicos, investigación, estadísticas y otros temas relacionados.

  10. Neuroblastoma–para profesionales de salud

    Cancer.gov

    Información del Instituto Nacional del Cáncer para profesionales de salud sobre el tratamiento y los exámenes de detección del neuroblastoma, así como referencias a estudios clínicos, investigación y otros temas relacionados con este tipo de cáncer.

  11. Neuroblastoma

    Cancer.gov

    Información del Instituto Nacional del Cáncer sobre el tratamiento y los exámenes de detección del neuroblastoma, así como referencias a estudios clínicos, investigación y otros temas relacionados con este tipo de cáncer.

  12. On-Site Wastewater Treatment Systems: Sand Filters (Spanish) 

    E-print Network

    Lesikar, Bruce J.; Enciso, Juan

    2000-10-13

    publicaciones, Sistemas individuales para el tratamiento de aguas negras, es resultado de la colaboraci?n de varias agencias, organizaciones y fuentes de financiamiento. Queremos reconocer a los siguientes colaboradores: Texas State Soil and Water Conservation...

  13. On-Site Wastewater Treatment Systems: Evapotranspiration Bed (Spanish) 

    E-print Network

    Lesikar, Bruce J.; Enciso, Juan

    2002-04-18

    individuales para el tratamiento de aguas negras, es resultado de la colaboraci?n de varias agencias, organizaciones y fuentes de financiamiento. Queremos reconocer a los siguientes colaboradores: Texas State Soil and Water Conservation Board USEPA 319(h...

  14. Mejor atención de niños con cáncer se asocia a esperanzas de vida más largas

    Cancer.gov

    Nuevos datos del Estudio sobre supervivientes de cánceres infantiles indican que las mejoras en el tratamiento de cánceres infantiles durante las últimas décadas han ayudado a extender la esperanza de vida de muchos supervivientes de cánceres infantiles.

  15. Carcinoma de tumor primario desconocido–para profesionales de salud

    Cancer.gov

    Información del Instituto Nacional del Cáncer para profesionales de salud sobre el tratamiento del carcinoma de tumor primario desconocido, así como referencias a estudios clínicos y otros temas relacionados.

  16. Conversion de las tablas del Lexico-Gramatica del frances en el lexico LGLex

    E-print Network

    Boyer, Edmond

    Introducci´on Los vol´umenes de informaci´on textual disponibles hoy en d´ia hacen imposible el tratamiento manual de la informaci´on, con lo cual el tratamiento autom´atico inteligente se convierte en una franc´es. El impacto est´a en aplicaciones muy diversas, desde extracci´on de informaci´on a apoyo al

  17. [Efficacy of racecadotril vs. smectite probiotics or zinc as an integral part of treatment of acute diarrhea in children under five years: A meta-analysis of multiple treatments].

    PubMed

    Gutiérrez-Castrellón, Pedro; Ortíz-Hernández, Anna Alejandra; Llamosas-Gallardo, Beatriz; Acosta-Bastidas, Mario A; Jiménez-Gutiérrez, Carlos; Diaz-García, Luisa; Anzo-Osorio, Anahí; Estevez-Jiménez, Juliana; Jiménez-Escobar, Irma; Vidal-Vázquez, Rosa Patricia

    2015-01-01

    Racional del estudio: A pesar de los grandes avances en su tratamiento, la diarrea aguda continúa representando un problema de salud pública en menores de cinco años. Existe poca sistematización en el tratamiento, y la mayor parte de publicaciones establecen comparaciones del coadyuvante con placebo. Objetivo: Analizar, mediante una revisión sistemática, la evidencia sobre la eficacia comparativa de los coadyuvantes para el tratamiento de la diarrea aguda y presentar las comparaciones a través de un meta-análisis de tratamientos múltiples. Métodos: Búsqueda sistematizada en múltiples bases de datos de todos los ensayos clínicos relacionados con la utilización de racecadotrilo, smectita, Lactobacillus GG, Lactobacillus reuteri, Sacharomyces boulardii y zinc como coadyuvantes en diarrea aguda, evaluando como desenlace primario la duración de la diarrea. Estadísticamente la información se analizó a través de la estrategia de meta-análisis de tratamientos múltiples, evaluando la superioridad de cada medicamento mediante un análisis SUCRA. Resultados: Se demuestra la eficacia del racecadotrilo al compararlo con placebo y con el resto de los coadyuvantes analizados. La evaluación de la superioridad terapéutica situó al racecadotrilo en primer lugar, seguido por smectita y, después, L. reuteri. Conclusión: Desde el punto de vista de toma estratégica de decisiones en salud, el meta-análisis de tratamientos múltiples nos permite establecer la superioridad terapéutica del racecadotrilo como coadyuvante en el manejo integral de la diarrea aguda en menores de cinco años. PMID:26089269

  18. Sampling Strategy

    NASA Technical Reports Server (NTRS)

    2008-01-01

    Three locations to the right of the test dig area are identified for the first samples to be delivered to the Thermal and Evolved Gas Analyzer (TEGA), the Wet Chemistry Lab (WCL), and the Optical Microscope (OM) on NASA's Phoenix Mars Lander. These sampling areas are informally labeled 'Baby Bear', 'Mama Bear', and 'Papa Bear' respectively. This image was taken on the seventh day of the Mars mission, or Sol 7 (June 1, 2008) by the Surface Stereo Imager aboard NASA's Phoenix Mars Lander.

    The Phoenix Mission is led by the University of Arizona, Tucson, on behalf of NASA. Project management of the mission is by NASA's Jet Propulsion Laboratory, Pasadena, Calif. Spacecraft development is by Lockheed Martin Space Systems, Denver.

  19. Update on the Status of the Space Telescope Imaging Spectrograph onboard the Hubble Space Telescope

    NASA Astrophysics Data System (ADS)

    Hernandez, Svea; Aloisi, A.; Bostroem, K. A.; Cox, C.; Debes, J. H.; DiFelice, A.; Roman-Duval, J.; Hodge, P.; Holland, S.; Lindsay, K.; Lockwood, S. A.; Mason, E.; Oliveira, C. M.; Penton, S. V.; Proffitt, C. R.; Sonnentrucker, P.; Taylor, J. M.; Wheeler, T.

    2013-06-01

    The Space Telescope Imaging Spectrograph (STIS) has been on orbit for approximately 16 years as one of the 2nd generation instruments on the Hubble Space Telescope (HST). Its operations were interrupted by an electronics failure in 2004, but STIS was successfully repaired in May 2009 during Service Mission 4 (SM4) allowing it to resume science observations. The Instrument team continues to monitor its performance and work towards improving the quality of its products. Here we present updated information on the status of the FUV and NUV MAMA and the CCD detectors onboard STIS and describe recent changes to the STIS calibration pipeline. We also discuss the status of efforts to apply a pixel-based correction for charge transfer inefficiency (CTI) effects to STIS CCD data. These techniques show promise for ameliorating the effects of ongoing radiation damage on the quality of STIS CCD data.

  20. A new analytical solution of water table response to tidal fluctuations and its application to estimate aquifer properties at the Niijima Island, Japan

    NASA Astrophysics Data System (ADS)

    Aichi, Masaatsu; Shiokari, Megumi; Tokunaga, Tomochika

    A perturbation solution of the Boussinesq equation under the boundary condition of multi-tide at the coast was derived for evaluating the hydraulic parameters of phreatic aquifer from tidally induced fluctuation of water table. Then, the solution was applied to estimate the hydraulic parameters of the Shiro-mama formation at the Niijima Island, Japan, by fitting the solution to the results of continuous measurements of water table fluctuations. The estimated hydraulic transmissivities from both the amplitude and the phase were comparable and consistent with the results of analyses based on Dupuit-Ghyben-Herzberg model, suggesting that the obtained values, i.e., 0.12-1.7 m2/s were reasonable.

  1. A new analytical approach to estimate the hydraulic parameters of a coastal phreatic aquifer from tidally induced water table fluctuations and its application at the Niijima Island, Japan

    NASA Astrophysics Data System (ADS)

    Aichi, M.; Shiokari, M.; Tokunaga, T.

    2010-12-01

    A new perturbation solution of the Boussinesq equation for tidally induced water table fluctuations in a coastal phreatic aquifer was derived under the condition of multiple tidal constituents. Then, the obtained solution was applied to estimate hydraulic parameters of the Shiro-mama formation at the Niijima Island, Japan, by fitting the solution to the results of continuous measurements of water table fluctuations in the frequency space. The estimated hydraulic transmissivities from both the amplitudes and the phase-shifts were comparable and consistent with the results of analyses based on the Dupuit-Ghyben-Herzberg model, suggesting that the proposed approach performed well and the obtained values, i.e., transmissivity to be 0.12-1.7 m2/s were reasonable.

  2. Concentrations of environmental phenols and parabens in milk, urine and serum of lactating North Carolina women.

    PubMed

    Hines, Erin P; Mendola, Pauline; von Ehrenstein, Ondine S; Ye, Xiaoyun; Calafat, Antonia M; Fenton, Suzanne E

    2015-07-01

    Phenols and parabens show some evidence for endocrine disruption in laboratory animals. The goal of the Methods Advancement for Milk Analysis (MAMA) Study was to develop or adapt methods to measure parabens (methyl, ethyl, butyl, propyl) and phenols (bisphenol A (BPA), 2,4- and 2,5-dichlorophenol, benzophenone-3, triclosan) in urine, milk and serum twice during lactation, to compare concentrations across matrices and with endogenous biomarkers among 34 North Carolina women. These non-persistent chemicals were detected in most urine samples (53-100%) and less frequently in milk or serum; concentrations differed by matrix. Although urinary parabens, triclosan and dichlorophenols concentrations correlated significantly at two time points, those of BPA and benzophenone-3 did not, suggesting considerable variability in those exposures. These pilot data suggest that nursing mothers are exposed to phenols and parabens; urine is the best measurement matrix; and correlations between chemical and endogenous immune-related biomarkers merit further investigation. PMID:25463527

  3. A Complex Two Dimensional Spectroscopic Database: The HST Treasury Archive for Eta Carinae

    NASA Technical Reports Server (NTRS)

    Humphreys, R. M.; Davidson, K.; Gray, M.; Koppelman, M. D.; Qian, A.; Martin, J. C.; Ishibashi, K.

    2004-01-01

    The HST Treasury Program on eta Carinae produced one of the most complex and ambitious spectroscopic datasets obtained with the Hubble Space Telescope. The archival database includes the STIS/CCD and MAMA data during its recent spectroscopic event in 2003, plus all of the STIS observations of the object and its ejecta obtained during its spectroscopic cycle beginning in 1998. The database permits users to query via instrument, target, date, wavelength range, position angle, and position and allows the user to display the spectrum and download it in fits format. We have also developed software for ease of extraction and display and analysis. The user can go from an initial query to doing science in only 20 minutes! A demonstration of the database and software will be available at the poster.

  4. Multidisciplinary collaborative development of a plain-language prenatal education book.

    PubMed

    Mottl-Santiago, Julie; Fox, Carolyn Shepard; Pecci, Christine Chang; Iverson, Ronald

    2013-01-01

    During pregnancy, women actively seek out health information that promotes the well-being of themselves and their fetuses. For those with health literacy challenges, access to understandable health information can be difficult. Written information, in particular, needs to be readable and usable by the women served. Plain language is an essential component of effective health education material. In an effort to create standardized prenatal education materials for a diverse population of childbearing women, Boston Medical Center's midwifery service led a multidisciplinary initiative to develop a comprehensive plain-language prenatal education book. Midwives, obstetricians, family physicians, nurses, and community doulas contributed to the content of the book; art students provided graphic design skills; and a literacy consultant assisted in the wording and layout. The Hey Mama! book provides women with woman-centered, readable, comprehensive information about pregnancy, labor, postpartum, and newborn care. PMID:23647968

  5. HIV seroprevalence among hospital workers in Kinshasa, Zaire: lack of association with occupational exposure

    SciTech Connect

    Mann, J.M.; Francis, H.; Quinn, T.C.; Bila, K.; Asila, P.K.; Bosenge, N.; Nzilambi, N.; Jansegers, L.; Piot, P.; Ruti, K.; Curran, J.W.

    1986-12-12

    A study of seroprevalence of the human immunodeficiency virus involving 2384 (96%) of Mama Yemo Hospital's (Kinshasa, Zaire) 2492 personnel found 152 (6.4%) to be seropositive. Prevalence was higher among women than among men (8.1% vs 5.2%); in women peak seroprevalence (13.9%) occurred in 20 to 29-year-olds. Workers most likely to be seropositive were those who were relatively young, those who were unmarried, those reporting a blood transfusion or hospitalization during the previous ten years, and those receiving medical injections during the previous three years. Medical, administrative, and manual workers had similar seroprevalence (6.5%, 6.4%, and 6.0%, respectively), and seropositivity was not associated with any measure of patient, blood, or needle contact. These findings are consistent with other hospital-based studies indicating low risks for occupational transmission of human immunodeficiency virus.

  6. Henry's Gallery

    NSDL National Science Digital Library

    Diltz, Henry.

    This site showcases the work of Henry Diltz, the official photographer of the Woodstock and Monterey Pop Festivals and over 100 album covers. Although the site is designed as a commercial enterprise (many of the photos can be ordered at the site), users are free to browse this collection of over 100 photos, some with brief notes, of many of the leading Rock and Roll musicians of the 1960s and 70s. Some of the photos were taken during posed sessions or album cover shoots, but many are candids to be found nowhere else. Highlights include shots of Joni Mitchell, David Crosby, and Eric Clapton in Mama Cass's backyard; Jerry Garcia jamming at Crosby's house; and the Who at the Monterey Pop Festival with a hapless engineer trying to save his microphones from Pete Townshend's flailing guitar. Additional resources include a brief special feature on Henry's recollections of Woodstock (with photos).

  7. Pre- and post-emergence weed control in bermudagrass turf 

    E-print Network

    Duble, Richard L

    1965-01-01

    -chlorobensene ar sonic acid 4-hydroxy-3-nitrobenzene arsonic acid Arsanilic acid AMA GAMA MAMA 5 12 15 7 15 7 15 7 2. 6 1. 0 0, 6 0. 4 1. 6 5. 0 4. 0 4. 0 2. 1 2. 2 1. 8 1. 6 1. 0 1. 1 100. 0 d 100. 0 d 100. 0 d 100. 0 d 100. 0.../19/63 1/ Ratin 8/21/63 8/23/63 8/25 /63 8/27/63 AMA GAMA MSMA MA MA DSMA DSMA + Dicryl Arsanilic acid 4-nit r obe n ze ne ar sonic acid. 4-hydroxy-3-nitro- benzene arsonic acid 4-chlorobenzene arsonic acid . Check 2. 6 l. 0 l. 0 0. 6 5...

  8. Keep Foodborne Illness from Spoiling Holiday Parties (Spanish) 

    E-print Network

    Nutrition, Food and

    2008-12-17

    , especialmente la carne cruda de res o de aves. ? Aseg?rese de que los utensilios y las ?reas donde prepara alimentos, incluso los mostradores y las tablas de cortar, est?n limpias. L?velos con jab?n y agua caliente tras cada uso. ? Despu?s de limpiarlos... la contaminaci?n cruzada. La contaminaci?n cruzada ocurre cuando alimentos son contaminados por bacterias de las manos, tablas para cortar, utensilios u otros alimentos tales como carne cruda de res o de aves. Adem?s de mantener limpias las manos y...

  9. Bestiario y metamorfosis en Santísima la nauyaca de Tomás Espinosa

    E-print Network

    Montes-Huidobro, Matí as

    1982-10-01

    FALL 1982 41 Bestiario y metamorfosis en Santísima la nauyaca de Tomás Espinosa Matías Montes Huidobro Cuando el estreno de la obra, Tomás Espinosa comenta en la nota al programa que la misma " nació como sueño de una noche de verano de..., un caimán, que tienen Isabelita y Josefa en la sala-comedor detrás de un cuadro de La Ultima Cena, y metido tras un vidrio. La función devoradora del yacaré se pone de manifiesto de inmediato, de una forma irreal, que va trasladando este bestiario...

  10. El teatro hispanoamericano de post mortem.

    E-print Network

    Schanzer, George O.

    1974-04-01

    realismo criollista facilitó el renacimiento de lo macabro. En efecto, la aparición de personajes muertos en las tablas es la mejor contra dicción de la ilusión dramática de un trozo de "vida." Entre las muchas maneras de abordar el tema de la muerte en... sucesos pasados, deseos, desengaños, exactamente como lo hubieran hecho vivos, hasta que suena a lo lejos una trompeta. Luego desaparecen uno tras otro los personajes y cae el telón. La trabazón de lo macabro con lo poético ya se manifiesta en los...

  11. The Tides Of Time Issue 29 

    E-print Network

    2010-01-01

    una amistad profunda y aunque Nieto se enamora de la esposa de Rosal?o, cuando entre Rosal?o y Lolita nace el peque?o Felipe, Nieto lo apadrina y entra en compadrazgo con Mendoza. Entre tanto, Rosal?o sigue haciendo tratos con ambas fuerzas y tras... zapatistas aun peleando. Felipe Nieto entra en una emboscada en la casa de Mendoza y es ahorcado desde el portal de la hacienda. El consternado Mendoza se fuga para la ciudad de M?xico con Lolita y el joven Felipe, esperando que all? prosperaran. Aun...

  12. Neuroimagen en la enfermedad de Alzheimer: nuevas perspectivas

    PubMed Central

    Becker, James T.

    2012-01-01

    Introducción y desarrollo En los próximos 50 años vamos a presenciar un incremento significativo de la población mayor de 65 años y por lo tanto va a aumentar, considerablemente, el número de individuos con riesgo de desarrollar demencias neurodegenerativas, especialmente la enfermedad de Alzheimer (EA). Las estrategias actuales de tratamiento farmacológico y no farmacológico se han centrado en las fases sintomáticas de esta enfermedad y, gradualmente, vamos teniendo una mayor comprensión de los posibles factores de riesgo del síndrome clínico. Conclusiones Los estudios de neuroimagen han sido muy útiles para mostrar los cambios estructurales del envejecimiento normal y patológico, así como también los factores de riesgo para la EA. Los tratamientos apropiados de los factores de riesgo y su posible combinación con tratamientos específicos para la EA podrían prolongar el período presintomático de la EA y, por tanto, mejorar la calidad de vida y disminuir la carga para el paciente, la familia y la sociedad. PMID:20517866

  13. Cáncer de piel–para profesionales de salud

    Cancer.gov

    Información del Instituto Nacional del Cáncer para profesionales de salud sobre el tratamiento, la prevención, las causas y los exámenes de detección del cáncer de piel, así como referencias a estudios clínicos, investigación y otros temas relacionados con este tipo de cáncer.

  14. CONTEXTO PRAGMÁTICO, GÉNEROS Y COMPRENSIÓN LECTORA DE RESÚMENES CIENTÍFICOS EN INGLÉS

    Microsoft Academic Search

    Piedad Fernández Toledo

    2000-01-01

    Resumen: El objetivo de este artículo es validar empíricamente la existencia de un componente en el conocimiento previo del lector, como son los esquemas de género o retóricos, a tener en cuenta tanto en la enseñanza de lenguas extranjeras, como en el análisis y tratamiento documental. Se defiende la inclusión de un componente pragmático que incluya el objetivo de comunicación

  15. Números: simplicidad conceptual, complejidad curricular

    Microsoft Academic Search

    Luis Rico Romero

    ¿De quién es el conocimiento sobre el número?, ¿quién determina su tratamiento curric- ular? Cuestiones similares han sido propuestas recientemente por Michael Apple ( ¿De quién es el conocimiento que más valor tiene?, ¿de quién es este curriculo? ), y se plantean en toda su crudeza cuando, como en la actualidad, se trabaja sobre modificaciones importantes del currícu- lo. En

  16. Los Derechos de los Pacientes del Centro Clnico

    E-print Network

    Los Derechos de los Pacientes del Centro Clínico Los Derechos de los Pacientes del Centro Clínico medir las respuestas de los pacientes al tratamiento. Existen procesos que protegen los derechos de paciente que se observen los derechos fundamentales de la dignidad humana. Esta Declaración de Derechos

  17. CRIA DE LARVAS DE RHAMDIA SAPO (VAL.) EIG. EN ESTANQUES PRIMEROS ENSAYOS

    Microsoft Academic Search

    Laura Luchini; Toribio Avendaño Salas

    1983-01-01

    RESUMEN El objetivo fue contribuir al desarrollo de metodologías de cultivo para larvas de bagre sapo, determinando el tipo adecuado de tratamiento previo en los estanques de cría, el alimento (natural o artificial) que mejor favorece su crecimiento, así como el tiempo de cultivo para esta etapa. Los primeros ensayos indicaron como más conveniente el procedimiento de fertilización previa con

  18. El equilibrio correcto: cómo ayudar a los supervivientes de cáncer a tener un peso saludable

    Cancer.gov

    La obesidad ha sido relacionada con un aumento en el riesgo de recidiva y muerte por varios tipos de cáncer. Existen intervenciones para ayudar a los supervivientes a mantener un peso saludable, reducir el riesgo de recidiva y muerte por cáncer y disminuir la probabilidad de padecer efectos tardíos y crónicos del tratamiento.

  19. Experto Universitario Java Enterprise 2012-2013 Depto. Ciencia de la Computacin e IA

    E-print Network

    Escolano, Francisco

    Experto Universitario Java Enterprise © 2012-2013 Depto. Ciencia de la Computación e IA Lenguaje Java Avanzado Sesión 3: Tratamiento de errores #12;Lenguaje Java Avanzado © 2012-2013 Depto. Ciencia de · Tipos genéricos #12;Lenguaje Java Avanzado © 2012-2013 Depto. Ciencia de la Computación e IA Errores - 3

  20. Haseltonia 14: 161169. 2008 161 1. Introduction

    E-print Network

    Zürich, Universität

    species occur in cen- Abstract: The most recent treatments of the family Cactaceae for Uruguay floccosa are new records for the flora of Uruguay. The occurrence of Epiphyllum phyllanthus in Uruguay could not be confirmed. Resumen: Los tratamientos mas recientes de la familia Cactaceae para Uruguay son

  1. COMPARACIÓN ENTRE LA TERAPIA CONVENCIONAL ODONTOLÓGICA Y SU USO COMBINADO CON LA FISIOTERAPIA Y LA OSTEOPATÍA, EN PACIENTES CON DISFUNCIÓN TEMPOROMANDÍBULAR. \\

    Microsoft Academic Search

    Graciela Carvallo; Maria Fasanella; Sofia Caricote

    RESUMEN Dado que la disfunción temporomandibular es una patología que cursa frecuentemente con, dolor y limitación en la apertura bucal los pacientes afectados reducen su calidad de vida desde el punto de vista social, laboral y familiar. La presente investigación tiene como propósito evaluar comparativamente los alcances terapéuticos entre el tratamiento odontológico convencional y el uso combinado de éste, con

  2. TOTAL MUJERES MSTER EN ESPACIOS NATURALES PROTEGIDOS. 32 17

    E-print Network

    Autonoma de Madrid, Universidad

    CUIDADOS PALIATIVOS Y TRATAMIENTO DE SOPORTE DEL ENFERMO NEOPLÁSICO 37 32 MÁSTER EN FISIOTERAPIA RESPIRATORIA Y CARDIACA (E.U. DE FISIOTERAPIA DE LA ONCE) 27 16 MÁSTER EN I + D DEL MEDICAMENTO 21 13 MÁSTER EN FISIOTERAPIA OSTEOARTICULAR (E.U. DE FISIOTERAPIA DE LA ONCE) 96 72 EXPERTO EN MEDICINA TROPICAL 50 41 TOTAL

  3. Ni genio ni farsante : Edgar Allan Poe y Eureka

    Microsoft Academic Search

    G. St. John Stott

    2009-01-01

    Eureka (1848) ha sido considerado superficialmente como una versión expandida de una conferencia sobre cosmología que Poe había dado ese mismo año. Sin embargo, la seriedad de este trabajo como un trabajo científico debería ser cuestionada. El tratamiento de algunos temas, que se encuentran en otros escritos de Poe, muestra que el autor no busca ser consistente. Entonces, el texto

  4. ESCUELA COMPLUTENSE LATINOAMERICANA Modelos de Simulacin Estocstica

    E-print Network

    Figueira, Santiago

    ;Modelos de Simulación- 3 I. Modelado de sistemas mediante simulación TRATAMIENTO DEL TIEMPO RELOJ DE cuenta instantes exactos (no error) 0 s1 s2 s3 #12;Modelos de Simulación- 5 I. Modelado de sistemas PROGRAMACIÓN Ejecutar y comparar con modelo 5. VALIDAR EL MODELO Ejecutar y comparar con sistema o solución

  5. Etapa final de la vida (PDQ®)

    Cancer.gov

    Sumario informativo revisado por expertos sobre el tratamiento y la atención del paciente de cáncer desde los últimos días hasta las últimas horas de vida; esto incluye los síntomas comunes, los dilemas éticos que pueden surgir y la función que desempeña el oncólogo en proveer cuidados al paciente y su familia durante este período.

  6. Cánceres infantiles

    Cancer.gov

    Los cánceres infantiles no siempre se tratan como los cánceres en adultos. La oncología pediátrica es una especialización médica que se concentra en la atención de niños con cáncer. Es importante saber que existen estos conocimientos especializados y que hay tratamientos eficaces para muchos cánceres infantiles.

  7. ¿Por Qué un Banco Público de Células Madre de Sangre de Cordon Umbilical en Colombia?

    Microsoft Academic Search

    JULIETA HENAO PÉREZ; EUGENIA CRISTINA; PACHECO PINEDO; GERMÁN DAVID; ARBOLEDA TORO; GÓMEZ ARISTIZABAL; LUZ MARINA; RESTREPO MÚNERA

    2005-01-01

    El trasplante de células madres hematopoyéticas (CMH) obtenidas de médula ósea (MO) se ha convertido en el tratamiento de elección para diferentes desórdenes hematológicos. Pero éste presenta dificultades, que pueden mejorarse con el uso de de sangre de cordón umbilical (SCU), fuente importante de CMH de rápida disponibilidad, fácil obtención, inofensivo para el donante, menor restricción de histocompatibilidad (HLA), menor

  8. SISTEMA DE INFORMACIÓN TURÍSTICO DESDE PRESUPUESTOS ECOLÓGICOS Y FOLKSONÓMICOS

    Microsoft Academic Search

    Iraimi Bermúdez García; Ramón Antonio Rodríguez Piña; Renier Castillo García; Ines Maria Marrero Ramírez

    2009-01-01

    El reto de diseñar e implementar un Sistema de Información, -y de ahora en lo adelante SI-, no resulta un ejercicio simple. El tratamiento a la información desde las perspectivas de Producto y Proceso de Gestión, conlleva a confusión e incertidumbre. Al certero decir de Alfons Cornella ... “Las organizaciones deben entender mejor en qué consiste la información, y deben

  9. Extraccion de lineas melodicas a partir de imagenes de partituras musicales

    E-print Network

    Pantrigo Fernández, Juan José

    encontrados en el estado del arte de los sistemas OMR (Optical Music Recognition) combinadas con aportaciones) [7]. La mayor parte de los sistemas que utilizan una representaci´on simb´olica de la imagen. Estas son las etapas t´ipicas de un sistema de tratamiento digital de im´agenes. La mayor´ia de los

  10. El análisis de las interacciones grupales: las aplicaciones SOCIOS

    Microsoft Academic Search

    José Manuel Cornejo Álvarez

    2006-01-01

    El concepto de ‘interacción’ representa uno de los núcleos fundamentales de la Psicología Social. En los grupos y las organizaciones, esto significa focalizar las explicaciones de los fenómenos en el sistema de relaciones de “influenciarecíproca” que se establece entre sus componentes. El análisis de las matrices de interacción requiere la utilización de algoritmos específicos de tratamiento de la información, no

  11. Nutrient Availability in Rangeland Soils: Influence of Prescribed Burning, Herbaceous Vegetation Removal, Overseeding with Bromus tectorum, Season, and Elevation

    E-print Network

    Removal, Overseeding with Bromus tectorum, Season, and Elevation R. R. Blank,1 J. Chambers,2 B. Roundy,3 prescribed burning, herbaceous vegetation removal, and controls. Cheatgrass (Bromus tectorum L´ Bromus tectorum L. en pequen~as subparcelas dentro de cada tratamiento. Posterior a la aplicacio´n de

  12. EL ABOGADO DEL NIÑO COMO GARANTE DEL PLENO EJERCICIO DE LOS DERECHOS DE LOS MENORES DE EDAD

    Microsoft Academic Search

    Lisbeth Rodríguez Martín; Yanelys Palmero Martín

    2012-01-01

    El tratamiento de la niñez y sus derechos resulta tema de interés universal para las ciencias jurídicas modernas, debido a las nuevas tendencias de protección surgidas a partir de la celebración de los Congresos Panamericanos del Niño y la Convención sobre los Derechos del Niño. De modo, que para las ciencias jurídicas cubanas se hace de suma importancia el estudio

  13. Bronchopulmonary dysplasia (pulmonologist's point of view)

    Microsoft Academic Search

    Carlos E. Sabogal Rosas; Isaac Talmaciu

    2008-01-01

    RESUMEN La displasia broncopulmonar describe los trastornos respiratorios crónicos asociados primariamente con el nacimiento prematuro y sus tratamientos. Su definición, factores de riesgo, características radiológicas y patológicas han evolucionado con el tiempo, debido a los cambios en los cuidados de los recién nacidos prematuros. Sus características clínicas involucran no sólo al sistema respiratorio sino también al cardiovascular, gastrointestinal y al

  14. IMPLICACIONES DEL MODELO DE ENSEÑANZA NATURAL DEL LENGUAJE EN LA INTERVENCION DE PERSONAS CON AUTISMO

    Microsoft Academic Search

    Pedro Gortázar

    Equipo CEPRI RESUMEN: El Modelo de Tratamiento Natural del Lenguaje constituye el para- digma de intervención actualmente más válido para hacer frente a los déficits sociales y comunicativos de las personas con autismo. En esta ponencia se discuten las implicaciones de este Modelo de cara a la formu- lación de objetivos curriculares, definición de criterios de respuesta, técnicas de entre-

  15. Trastorno por déficit de atención con hiperactividad: orientaciones psicoeducativas para los padres

    Microsoft Academic Search

    López Villalobos; S. Alberola López; José Antonio López Villalobos

    2008-01-01

    Resumen Se exponen orientaciones psicoeducativas para padres de niños con trastorno por déficit de atención con hiperactividad (TDAH), basadas en criterios empíricos, teóricos y clínicos, abor- dando las siguientes dimensiones: ambiente familiar, modelado, refuerzo de conducta, normas, autonomía y autoestima, aprender a pensar y saber esperar, atención, relación con compañeros, grupo familiar, adolescencia y una reflexión sobre el tratamiento. Palabras

  16. Histamine release and mast cell degranulation induced by 2-4 dinitrophenol in rat tissues

    Microsoft Academic Search

    Mercedes P. de Oliveira Antonio; A. M. Rothschild

    1969-01-01

    Resumen El 2–4-dinitrofenol es capaz de producir degranulación rápida aunque parcial de mastocitos y liberación de histamina de los tejidos de la rata in vitro. Estos efectos solamente pueden ser demostrados en tejidos mantenidos a baja temperatura antes del tratamiento; son inhibidos por glucosa. La estimulación del consumo de oxígeno no parece ser la causa de los efectos del dinitrofenol.

  17. Formacin Integral en Odontologa

    E-print Network

    Rey Juan Carlos, Universidad

    Formación Integral en Odontología para el Auxiliar y el Higienista Dental III Edición INFORMACIÓN PLAZAY MATRÍCULA Título: : Formación Integral en Odontología para el Auxiliar y el Higienista Dental. III caries y radiología · Diagnóstico precoz de la caries. · Tratamiento no operatorio de la caries

  18. 12. Laboratorios de investigacin 12.1. Laboratorio de Conducta y Sistemas Dinmicos (LabCSD)

    E-print Network

    Oro, Daniel

    educadores sobre problemas infantiles, evaluación del Trastorno por Déficit de Atención e Hiperactividad o de, evaluación de trastornos emocionales o tratamiento del miedo a volar en avión y de otras fobias específicas, entre otros trastornos ansiosodepresivos. Proyectos de investigación en curso: -- Estudio aleatorio

  19. La teoría económica y financiera del precio: dos enfoques complementarios

    Microsoft Academic Search

    Javier Bernardo Cadena Lozano

    2011-01-01

    resumen El análisis de los precios ha sido abordado desde varios enfoques y por ello su tratamiento difiere. No puede decirse que éstos son excluyentes; por el contrario, existe una fuerte relación entre ellos, la que, sin embargo, poco se reconoce en el ámbito académico y empresarial de los teóricos de las finanzas y el marketing, por desconocer la fundamentación

  20. 11.1.9. Servicio de Prevencin La doctora Francesca Garcias, profesora titular del Departamento de Fsica, se ha

    E-print Network

    Oro, Daniel

    personal investigador en formación. También se han realizado diversos estudios sobre riesgos específicos y 17 incidentes sin baja, y se ha realizado la investigación pertinente en cada caso. Planes de); 16 de evaluación, tratamiento y seguimiento de casos psicosociales individuales, y 10 consultas y

  1. SMALL MAMMALS AND GROUND-DWELLING INVERTEBRATES ASSOCIATED WITH ACTIVE AND CONTROLLED COLONIES OF

    E-print Network

    Wallace, Mark C.

    OF BLACK-TAILED PRAIRIE DOGS (CYNOMYS LUDOVICIANUS) RACHEL E. MCCAFFREY,* MARK C. WALLACE, AND JAMES D. RAY (Cynomys ludovicianus), PhostoxinH-treated colonies, and non- colonized short-grass prairie to assess de las praderas de cola negra (Cynomys ludovicianus), en colonias con tratamiento de PhostoxinH, y en

  2. B8. RESPUESTA DE GYPSOPHILA (Gypsophila paniculata var. Bambino) A LA INYECCIÓN DE CO 2 EN SUS DIFERENTES FASES FENOLÓGICAS. GUAYLLABAMBA, PICHINCHA*. RESPONSE OF GYPSOPHILA (Gypsophila paniculata var. Bambino) TO THE INJECTION OF CO 2 IN DIFFERENT PHENOLOGIC PHASES. GUAYLLABAMBA, PICHINCHA

    Microsoft Academic Search

    con cuatro repeticiones. La unidad experimental net a fue 20m 2 (20mx1m). Las variables evaluadas fueron: Incremento de altura y diámetro, número de brotes, producción de tallos, peso de tallos en verde, determinación de m ateria seca, peso de tallos en blanca, número de días de apertura de flor, número de días en florero y análisis económico. El tratamiento que

  3. Añadir quimioterapia después de la radioterapia mejora la supervivencia de adultos con un tipo de tumor cerebral de crecimiento lento

    Cancer.gov

    Adultos con gliomas de grado bajo, una forma de tumor cerebral, que recibieron tratamiento con quimioterapia después de la radioterapia vivieron más tiempo que pacientes que recibieron solo radioterapia, según los resultados de seguimiento a largo plazo de un estudio clínico aleatorizado y controlado, subvencionado por los NIH.

  4. "La escenificacin del espacio del santo en dos obras de Lope de Vega : Barln y Josaf y El santo negro Rosambuco"

    E-print Network

    Boyer, Edmond

    1 17/02/2010 "La escenificación del espacio del santo en dos obras de Lope de Vega : Barlán y piezas, la inventiva de Lope de Vega resuelve la puesta en teatro del espacio propuesto por la fuente según los episodios, se traduce por técnicas diversas de tratamiento del espacio dramático, y por otra

  5. On-Site Wastewater Treatment Systems: Leaching Chambers (Spanish) 

    E-print Network

    Lesikar, Bruce J.; Enciso, Juan

    2000-10-13

    cada 3 a?os. Si se lleva a cabo un mantenimiento m?s frecuente el costo aumentar?. La serie de publicaciones, Sistemas individuales para el tratamiento de aguas negras, es resultado de la colaboraci?n de varias agencias, organizaciones y fuentes de...

  6. Sepsis por Salmonella enteritidis en una paciente con lupus eritematoso sistémico

    Microsoft Academic Search

    Carlos Alberto Cañas; Gustavo Adolfo Ospina; María Elena Ochoa; Juan Diego Vélez

    Resumen Presentamos el caso clínico de una paciente de 28 años de edad con Lupus Eritematoso Sistémico (LES), con compromiso a nivel neurológico central, riñón y sistema hematológico, con tratamiento cró- nico de esteroides y desnutrición avanzada, quien desarrolla sepsis por Salmonella enteritidis, germen aislado en muestras tomadas en lavado bronco alveolar, sangre y materia fecal. Presentó un absce- so

  7. Collective modes of a one-dimensional trapped atomic Bose gas at finite temperatures

    NASA Astrophysics Data System (ADS)

    Hu, Hui; Xianlong, Gao; Liu, Xia-Ji

    2014-07-01

    We theoretically investigate collective modes of a one-dimensional (1D) interacting Bose gas in a harmonic tras at finite temperatures, by using a variational approach and the local density approximation. We find that the temperature dependence of collective mode frequencies is notably different in the weakly and strongly interacting regimes. Therefore, the experimental measurement of collective modes could provide a sensitive probe for different quantum phases of a 1D trapped Bose gas, realized by tuning the interatomic interaction strength and temperature. Our prediction on the temperature dependence of the breathing mode frequency is in good qualitative agreement with an earlier experimental measurement for a weakly interacting 1D Bose gas of rubidium-87 atoms in harmonic traps [Moritz et al., Phys. Rev. Lett. 91, 250402 (2003), 10.1103/PhysRevLett.91.250402].

  8. The deacetylase Sirt1 is an essential regulator of Aire-mediated induction of central immunological tolerance.

    PubMed

    Chuprin, Anna; Avin, Ayelet; Goldfarb, Yael; Herzig, Yonatan; Levi, Ben; Jacob, Adi; Sela, Asaf; Katz, Shir; Grossman, Moran; Guyon, Clotilde; Rathaus, Moran; Cohen, Haim Y; Sagi, Irit; Giraud, Matthieu; McBurney, Michael W; Husebye, Eystein S; Abramson, Jakub

    2015-07-01

    Aire is a transcriptional regulator that induces the promiscuous expression of thousands of tissue-restricted antigens (TRAs) in medullary thymic epithelial cells (mTECs), a step critical for the induction of immunological self-tolerance. Studies have offered molecular insights into how Aire operates, but more comprehensive understanding of this process still remains elusive. Here we found abundant expression of the protein deacetylase Sirtuin-1 (Sirt1) in mature Aire(+) mTECs, wherein it was required for the expression of Aire-dependent TRA-encoding genes and the subsequent induction of immunological self-tolerance. Our study elucidates a previously unknown molecular mechanism for Aire-mediated transcriptional regulation and identifies a unique function for Sirt1 in preventing organ-specific autoimmunity. PMID:26006015

  9. Broadband performance of a moving time reversing array.

    PubMed

    Sabra, Karim G; Dowling, David R

    2003-09-01

    Acoustic time reversal exploits reciprocity between sources and receivers to generate backward propagating waves that automatically focus at their point of origin. In underwater acoustics, an array of transducers that can both transmit and receive, referred to as a time reversing array (TRA) or time reversal mirror (TRM), generates the back-propagating waves. Such arrays have been shown to spatially and temporally focus sound in unknown complicated multipath environments, and are therefore of interest for active sonar and underwater communication applications. Although stationary vertical linear TRAs have been favored in prior studies, practical applications of acoustic time reversal in underwater environments are likely to involve towed, tilted, horizontal, or bottom-mounted arrays. In particular, array motion introduces Doppler effects and eliminates source-receiver reciprocity, two factors that potentially impact the automatic focusing capability of TRAs. This paper presents the results from a theoretical and computational investigation into how array motion and orientation influence TRA retrofocusing in the shallow ocean. Here, the TRA tow speed is assumed constant, and the array is assumed to be straight and linear (vertical, horizontal, or tilted). And, for simplicity, the TRA is assumed to respond to a stationary point source emitting a broadband pulse. When a TRA moves, the retrofocus is predicted to shift in the direction of array motion due to the translation of the array between its reception and broadcast times. In addition, the performance of a towed horizontal TRA is predicted to degrade more rapidly with towing speed than that of an equivalent (but clearly idealized) towed vertical array because of range-dependent Doppler phase differences that do not influence the vertical array. However, short tilted arrays may approach vertical array performance and appear to be a potentially versatile compromise for implementing TRA concepts in active sonar or underwater communication systems. PMID:14514192

  10. Broadband performance of a moving time reversing array

    NASA Astrophysics Data System (ADS)

    Sabra, Karim G.; Dowling, David R.

    2003-09-01

    Acoustic time reversal exploits reciprocity between sources and receivers to generate backward propagating waves that automatically focus at their point of origin. In underwater acoustics, an array of transducers that can both transmit and receive, referred to as a time reversing array (TRA) or time reversal mirror (TRM), generates the back-propagating waves. Such arrays have been shown to spatially and temporally focus sound in unknown complicated multipath environments, and are therefore of interest for active sonar and underwater communication applications. Although stationary vertical linear TRAs have been favored in prior studies, practical applications of acoustic time reversal in underwater environments are likely to involve towed, tilted, horizontal, or bottom-mounted arrays. In particular, array motion introduces Doppler effects and eliminates source-receiver reciprocity, two factors that potentially impact the automatic focusing capability of TRAs. This paper presents the results from a theoretical and computational investigation into how array motion and orientation influence TRA retrofocusing in the shallow ocean. Here, the TRA tow speed is assumed constant, and the array is assumed to be straight and linear (vertical, horizontal, or tilted). And, for simplicity, the TRA is assumed to respond to a stationary point source emitting a broadband pulse. When a TRA moves, the retrofocus is predicted to shift in the direction of array motion due to the translation of the array between its reception and broadcast times. In addition, the performance of a towed horizontal TRA is predicted to degrade more rapidly with towing speed than that of an equivalent (but clearly idealized) towed vertical array because of range-dependent Doppler phase differences that do not influence the vertical array. However, short tilted arrays may approach vertical array performance and appear to be a potentially versatile compromise for implementing TRA concepts in active sonar or underwater communication systems.

  11. Far-Ultraviolet Imaging of the Hubble Deep Field North: Star Formation in Normal Galaxies at z<1

    E-print Network

    H. I. Teplitz; B. Siana; T. M. Brown; R. Chary; J. W. Colbert; C. Conselice; D. F. de Mello; M. Dickinson; H. C. Ferguson; Jonathan P. Gardner; F. Menanteau; ;

    2006-06-10

    We present far-ultraviolet (FUV) imaging of the Hubble Deep Field North (HDF-N) taken with the Solar Blind Channel of the Advanced Camera for Surveys (ACS/SBC) and the FUV MAMA detector of the Space Telescope Imaging Spectrograph (STIS) onboard the Hubble Space Telescope. The full WFPC2 deep field has been observed at 1600 Angstroms. We detect 134 galaxies and one star down to a limit of FUV_{AB} ~ 29. All sources have counterparts in the WFPC2 image. Redshifts (spectroscopic or photometric) for the detected sources are in the range 0UV vs. Beta relationship. We infer star formation rates (SFRs), corrected for extinction using the UV slope, and find a median value of 0.3 Msun/yr for FUV-detected galaxies, with 75% of detected sources have SFR<1 Msun/yr. Examining the morphological distribution of sources, we find that about half of all FUV-detected sources are identied as spiral galaxies. Half of morphologically-selected spheroids at z<0.85 are detected in the FUV, suggesting that such sources have significant ongoing star-formation in the epoch since z=1.

  12. Proteomic analysis of irregular, bullet-shaped magnetosomes in the sulphate-reducing magnetotactic bacterium Desulfovibrio magneticus RS-1.

    PubMed

    Matsunaga, Tadashi; Nemoto, Michiko; Arakari, Atsushi; Tanaka, Masayoshi

    2009-06-01

    Recent molecular studies on magnetotactic bacteria have identified a number of proteins associated with bacterial magnetites (magnetosomes) and elucidated their importance in magnetite biomineralisation. However, these analyses were limited to magnetotactic bacterial strains belonging to the alpha-subclass of Proteobacteria. We performed a proteomic analysis of magnetosome membrane proteins in Desulfovibrio magneticus strain RS-1, which is phylogenetically classified as a member of the delta-Proteobacteria. In the analysis, the identified proteins were classified based on their putative functions and compared with the proteins from the other magnetotactic bacteria, Magnetospirillum magneticum AMB-1 and M. gryphiswaldense MSR-1. Three magnetosome-specific proteins, MamA (Mms24), MamK, and MamM, were identified in strains RS-1, AMB-1, and MSR-1. Furthermore, genes encoding ten magnetosome membrane proteins, including novel proteins, were assigned to a putative magnetosome island that contains subsets of genes essential for magnetosome formation. The collagen-like protein and putative iron-binding proteins, which are considered to play key roles in magnetite crystal formation, were identified as specific proteins in strain RS-1. Furthermore, genes encoding two homologous proteins of Magnetococcus MC-1 were assigned to a cryptic plasmid of strain RS-1. The newly identified magnetosome membrane proteins might contribute to the formation of the unique irregular, bullet-shaped crystals in this microorganism. PMID:19579222

  13. Digging Movie from Phoenix's Sol 18

    NASA Technical Reports Server (NTRS)

    2008-01-01

    The Surface Stereo Imager on NASA's Phoenix Mars Lander recorded the images combined into this movie of the lander's Robotic Arm enlarging and combining the two trenches informally named 'Dodo' (left) and 'Goldilocks.'

    The 21 images in this sequence were taken over a period of about 2 hours during Phoenix's Sol 18 (June 13, 2008), or the 18th Martian day since landing.

    The main purpose of the Sol 18 dig was to dig deeper for learning the depth of a hard underlying layer. A bright layer, possibly ice, was increasingly exposed as the digging progressed. Further digging and scraping in the combined Dodo-Goldilocks trench was planned for subsequent sols.

    The combined trench is about 20 centimeters (about 8 inches) wide. The depth at the end of the Sol 18 digging is 5 to 6 centimeters (about 2 inches).

    The Goldilocks trench was the source of soil samples 'Baby Bear' and 'Mama Bear,' which were collected on earlier sols and delivered to instruments on the lander deck. The Dodo trench was originally dug for practice in collecting and depositing soil samples.

    The Phoenix Mission is led by the University of Arizona, Tucson, on behalf of NASA. Project management of the mission is by NASA's Jet Propulsion Laboratory, Pasadena, Calif. Spacecraft development is by Lockheed Martin Space Systems, Denver.

  14. A multi-wavelength study of the merger candidate Abell S0721 and the activities of its member galaxies

    NASA Astrophysics Data System (ADS)

    Ho, P.-L.; Chen, L.-W.

    We present a multi-wavelength study of the merging history and its influence on galaxy activities of a newly detected merger candidate - Abell S0721 This cluster was only known as a poor cluster in the Shapley Supercluster but when several survey data of different wavelengths are combined evidence of strong merging is revealed We have analyzed the optical and X-ray structures of the cluster as well as galaxy dynamics and properties of the radio galaxies in the cluster The dynamics analysis shows the velocity distribution of this system is significantly deviated from one Gaussian model indicating existence of 2-3 dynamically different sub-systems in addition the optical and X-ray structures both show an elongated and multi-clumps structure two X-ray clumps imaged by ROSAT All Sky Survey are well related to two galaxy density peaks based on MAMA digitized catalogue from Paris Observatory Finally the radio galaxies identified in Abell S0721 are all optically luminous as compared with other merger candidates in the Shapley Supercluster the fraction of bright radio galaxies is only lower than one merger candidate this suggests Abell S0721 is also at the beginning of a merger event The cluster is possibly a merger of several groups the main two merging groups might be seen at near the projection plane and a few tenth Gyr around the core passage The merging process could also be an origin to boost the activities of its member galaxies

  15. The Solar Neighborhood. XXXI. Discovery of an Unusual Red+White Dwarf Binary at ~25 pc via Astrometry and UV Imaging

    NASA Astrophysics Data System (ADS)

    Jao, Wei-Chun; Henry, Todd J.; Subasavage, John P.; Winters, Jennifer G.; Gies, Douglas R.; Riedel, Adric R.; Ianna, Philip A.

    2014-01-01

    We report the discovery of a nearby M5.0V dwarf at 24.6 pc, SCR 1848-6855, that is orbited by an unusual companion causing an astrometric perturbation of more than 200 mas. This is by far the largest perturbation found to date among more than 700 targets observed during our long-term astrometry/photometry program at the CTIO 0.9 m telescope. We present here a suite of astrometric, photometric, and spectroscopic observations of this high proper motion (~1.''3 yr-1) system in an effort to reveal the nature of this unusual binary. The measured near-UV and optical U band fluxes exceed those expected for comparable M5.0V stars, and excess flux is also detected in the spectral range 4000-7000 Å. The elusive companion has been detected in HST-STIS+MAMA images at 1820 Å and 2700 Å, and our analysis shows that it is probably a rare, cool, white dwarf with T = 4600-5500 K. Given the long-term astrometric coverage, the prospects for an accurate mass determination are excellent, although as yet we can only provide limits on the unusual companion's mass.

  16. The solar neighborhood. XXXI. Discovery of an unusual red+white dwarf binary at ?25 pc via astrometry and UV imaging

    SciTech Connect

    Jao, Wei-Chun; Henry, Todd J.; Winters, Jennifer G.; Gies, Douglas R. [Department of Physics and Astronomy, Georgia State University, Atlanta, GA 30302 (United States); Subasavage, John P. [US Naval Observatory, Flagstaff Station, 10391 West Naval Observatory Road, Flagstaff, AZ 86001 (United States); Riedel, Adric R. [Department of Physics and Astronomy, Hunter College, 695 Park Avenue, New York, NY 10065 (United States); Ianna, Philip A., E-mail: jao@chara.gsu.edu, E-mail: thenry@chara.gsu.edu, E-mail: winters@chara.gsu.edu, E-mail: gies@chara.gsu.edu, E-mail: jsubasavage@nofs.navy.mil, E-mail: ar494@hunter.cuny.edu, E-mail: philianna3@gmail.com [Department of Astronomy, University of Virginia, Charlottesville, VA 22904-4325 (United States)

    2014-01-01

    We report the discovery of a nearby M5.0V dwarf at 24.6 pc, SCR 1848–6855, that is orbited by an unusual companion causing an astrometric perturbation of more than 200 mas. This is by far the largest perturbation found to date among more than 700 targets observed during our long-term astrometry/photometry program at the CTIO 0.9 m telescope. We present here a suite of astrometric, photometric, and spectroscopic observations of this high proper motion (?1.''3 yr{sup –1}) system in an effort to reveal the nature of this unusual binary. The measured near-UV and optical U band fluxes exceed those expected for comparable M5.0V stars, and excess flux is also detected in the spectral range 4000-7000 Å. The elusive companion has been detected in HST-STIS+MAMA images at 1820 Å and 2700 Å, and our analysis shows that it is probably a rare, cool, white dwarf with T = 4600-5500 K. Given the long-term astrometric coverage, the prospects for an accurate mass determination are excellent, although as yet we can only provide limits on the unusual companion's mass.

  17. Population prevalence of hereditary breast cancer phenotypes and implementation of a genetic cancer risk assessment program in southern Brazil.

    PubMed

    Palmero, Edenir I; Caleffi, Maira; Schüler-Faccini, Lavínia; Roth, Fernanda L; Kalakun, Luciane; Netto, Cristina Brinkmann Oliveira; Skonieski, Giovana; Giacomazzi, Juliana; Weber, Bernadete; Giugliani, Roberto; Camey, Suzi A; Ashton-Prolla, Patricia

    2009-07-01

    In 2004, a population-based cohort (the Núcleo Mama Porto Alegre - NMPOA Cohort) was started in Porto Alegre, southern Brazil and within that cohort, a hereditary breast cancer study was initiated, aiming to determine the prevalence of hereditary breast cancer phenotypes and evaluate acceptance of a genetic cancer risk assessment (GCRA) program. Women from that cohort who reported a positive family history of cancer were referred to GCRA. Of the 9218 women enrolled, 1286 (13.9%) reported a family history of cancer. Of the 902 women who attended GCRA, 55 (8%) had an estimated lifetime risk of breast cancer ? 20% and 214 (23.7%) had pedigrees suggestive of a breast cancer predisposition syndrome; an unexpectedly high number of these fulfilled criteria for Li-Fraumeni-like syndrome (122 families, 66.7%). The overall prevalence of a hereditary breast cancer phenotype was 6.2% (95%CI: 5.67-6.65). These findings identified a problem of significant magnitude in the region and indicate that genetic cancer risk evaluation should be undertaken in a considerable proportion of the women from this community. The large proportion of women who attended GCRA (72.3%) indicates that the program was well-accepted by the community, regardless of the potential cultural, economic and social barriers. PMID:21637504

  18. EUV, X-ray, and Gamma-ray instrumentation for astronomy; Proceedings of the Meeting, San Diego, CA, July 11-13, 1990

    SciTech Connect

    Siegmund, O.H.W.; Hudson, H.S. (California Univ., Berkeley (United States) California Univ., La Jolla (United States))

    1990-01-01

    Various papers on EUV, X-ray, and gamma-ray instrumentation for astronomy are presented. Individual topics addressed include: performance of lithium scatterers for X-ray polarimetry, shared X-ray concentration via crystal diffraction, optimum shields for spaceborne gamma-ray spectrometers, position-sensitive high-resolution spectrometer, IPCs for stellar X-ray polarimeter, soft X-ray windows for position-sensitive proportional counters, EUV imaging telescope array on the spectrum X-G satellite, European Photon Imaging Camera for X-ray astronomy, development of a UV auroral imager, background reduction in microchannel plates, 2D delay-line anode detector for astronomical imaging, dynamic range considerations for EUV MAMA detectors, Rosat WFD imaging detectors. Also discussed are: EUV band-pass filters for the Rosat wide-field camera, calibration of the Rosat High-Resolution Imager, superconducting tunneling junction detectors, test results of a prototype dielectric microcalorimeter, novel high-speed high-resolution position readout SPAN, after emission in microchannel plate detectors, highly curved microchannel plates, soft X-ray performance of back-illuminated EEV CCDs, proton damage effects in EEV CCDs, PN-CCDs for the XMM satellite mission, intensified CCD detectors using the phosphor TPB, silicon X-ray array detector concept, multilayer telescope for soft X-ray surveys, hard X-ray and soft gamma-ray astronomy mission EXOS.

  19. Proper Motions of Pre-Main Sequence Stars in Southern Star-Forming Regions

    E-print Network

    R. Teixeira; C. Ducourant; M. J. Sartori; J. I. B. Camargo; J. P. Perié; J. R. D. Lépine; P. Benevides-Soares

    2000-08-24

    We present proper motion measurements of pre-main sequence (PMS) stars associated with major star-forming regions of the southern hemisphere (Chamaeleon, Lupus, Upper Scorpius - Ophiuchus, Corona Australis), situated in the galactic longitude range l = 290\\degr to l = 360\\degr. A list of PMS stars as complete as possible was established based on the Herbig and Bell catalogue and many new catalogues like the PDS survey, the catalogue of Herbig Ae/Be stars by Th\\'e et al. (1994), X-rays surveys, etc. The measurements made use of public material (mainly AC2000 and USNO--A2.0 catalogues) as well as scans of SERC-J Schmidt plates with the MAMA measuring machine (Paris) and Valinhos CCD meridian circle observations (Brazil). We derived proper motions for 214 stars, with an accuracy of 5 to 10 mas/yr depending mainly on the difference of epochs between the position sources. The main characteristics of the sample are discussed. We show that systematic motions of groups of stars exist, which are not explained by the reflex solar motion.

  20. VizieR Online Data Catalog: Proper motions of PMS stars (Teixeira+ 2000)

    NASA Astrophysics Data System (ADS)

    Teixeira, R.; Ducourant, C.; Sartori, M. J.; Camargo, J. I. B.; Perie, J. P.; Lepine, J. R. D.; Benevides-Soares, P.

    2000-10-01

    We present proper motion measurements of pre-main sequence (PMS) stars associated with major star-forming regions of the southern hemisphere (Chamaeleon, Lupus, Upper Scorpius - Ophiuchus, Corona Australis), situated in the galactic longitude range l=290° to l=360°. A list of PMS stars as complete as possible was established based on the Herbig and Bell (1988LicOB1111....1H) catalogue and many new catalogues like the PDS survey, the catalogue of Herbig Ae/Be stars by The et al. (1994A&AS..104..315T), X-rays surveys, etc. The measurements made use of public material (mainly AC2000 and USNO-A2.0 catalogues) as well as scans of SERC-J Schmidt plates with the MAMA measuring machine (Paris) and Valinhos CCD meridian circle observations (Brazil). We derived proper motions for 213 stars, with an accuracy of 5 to 10mas/yr depending mainly on the difference of epochs between the position sources. The main characteristics of the sample are discussed. We show that systematic motions of groups of stars exist, which are not explained by the reflex solar motion. (3 data files).

  1. Proper Motions of Pre-Main Sequence Stars in Southern Star-Forming Regions

    E-print Network

    Teixeira, R G; Sartori, M J; Camargo, J I B; Perié, J P; Lépine, J R D; Benevides-Soares, P

    2000-01-01

    We present proper motion measurements of pre-main sequence (PMS) stars associated with major star-forming regions of the southern hemisphere (Chamaeleon, Lupus, Upper Scorpius - Ophiuchus, Corona Australis), situated in the galactic longitude range l = 290\\degr to l = 360\\degr. A list of PMS stars as complete as possible was established based on the Herbig and Bell catalogue and many new catalogues like the PDS survey, the catalogue of Herbig Ae/Be stars by Th\\'e et al. (1994), X-rays surveys, etc. The measurements made use of public material (mainly AC2000 and USNO--A2.0 catalogues) as well as scans of SERC-J Schmidt plates with the MAMA measuring machine (Paris) and Valinhos CCD meridian circle observations (Brazil). We derived proper motions for 214 stars, with an accuracy of 5 to 10 mas/yr depending mainly on the difference of epochs between the position sources. The main characteristics of the sample are discussed. We show that systematic motions of groups of stars exist, which are not explained by the r...

  2. Proper Motions of Pre-Main Sequence stars in Southern Star-forming Regions

    NASA Astrophysics Data System (ADS)

    Ducourant, C.; Teixeira, R.; Sartori, M. J.; Camargo, J. I. B.; Perié, J. R.; Lépine, J. R. D.; Benevides-Soares, P.

    The HIPPARCOS mission provided very important and accurate measurements of parallaxes, positions and proper motions for about 120,000 stars. Among them, many OB and pre-main sequence (PMS) stars associated with the major star-forming regions of the southern hemisphere (Chamaeleon, Lupus, Upper Scorpius-Ophiuchus) allow the study of the kinematics of these regions and a comparison of the space velocities of different groups of stars. However, since most PMS stars are fainter than the limiting magnitude of HIPPARCOS, the total number of measured PMS stars is still small. In this work, we present proper motion measurements for a list of PMS stars in these regions, compiled from the Herbig and Bell catalogue and many new catalogues like the PDS survey, the catalogue of Herbig Ae/Be stars by The et al. (1994), X-rays surveys, etc. The measurements made use of published material (mainly AC2000 and USNO-A2.0 catalogues) as well as scans of SERC-J Schmidt plates with the MAMA measuring machine (Paris Observatory) and Valinhos (Brazil) CCD meridian circle observations. We derived proper motions for 223 stars, with accuracies ranging from 5 to 10 mas/yr, and we discuss here some characteristics of the sample and show that systematic motions of groups of stars exist.

  3. Magnetic edge states and mixed-parity pairing in spin-triplet superconductors

    NASA Astrophysics Data System (ADS)

    Cuoco, Mario; Gentile, Paola; Noce, Canio; Vekhter, Ilya; Romano, Alfonso

    2014-03-01

    We show that a spontaneous magnetic moment may appear at the edge of a spin-triplet superconductor if the system allows for pairing in a subdominant channel and non-uniform spatial profile. To unveil the microscopic mechanism behind such effect we combine numerical solution of the Bogoliubov-De Gennes equations for a tight-binding model with nearest-neighbor attraction, and the symmetry based Ginzburg-Landau approach. We find that a modulation of the electronic density near the edge of the system leads to a non-unitary superconducting state where spin-singlet pairing coexists with the dominant triplet superconducting order. We demonstrate that the spin polarization at the edge appears due to the inhomogeneity of the non-unitary state and originates in the lifting of the spin-degeneracy of the Andreev bound-states. For chiral spin-triplet superconductors spin current flows along the interface and surface charge currents exhibit anomalous dependence on the magnetization. - A. Romano, P. Gentile, C. Noce, I. Vekhter, M. Cuoco, Phys. Rev. Lett. 110, 267002 (2013). This research has received funding from the EU -FP7/2007-2013 under grant agreement N. 264098 - MAMA, and was supported in part by US NSF via Grant No. DMR-1105339

  4. [Impact of taxanes in the adjuvant setting of node-negative breast cancers].

    PubMed

    Lagha, Aymen; Chraiet, Nesrine; Labidi, Soumaya; Krimi, Sarra; Ayadi, Mouna; Gligorov, Joseph; Boussen, Hamouda

    2013-05-01

    The use of regimens with adjuvant taxanes reduces the risk of recurrence and improves survival in patients with node-positive breast cancer, but the use of taxanes in node-negative breast cancer is still to be defined. The aim of this study is to evaluate the role of taxanes in high-risk node-negative breast cancer. Two categories of studies were reviewed: studies that evaluated both node-positive and node-negative breast cancers, and studies that included only high-risk node-negative breast cancers. Three phase-III studies that evaluated both negative and positive nodes did not show any benefit of the use of taxanes according to the node-negative subgroup analyses, versus two studies (European Cooperative Trial in Operable Breast Cancer [ECTO] et Grupo Español de Investigación del Cáncer de Mama [GEICAM]) that showed a significant difference in disease-free survival. In view of these studies, the role of taxanes in node-negative breast cancer is still controversial and the results of the ongoing trials may respond to this subject. PMID:23613145

  5. [Cost-effectiveness of an organized breast cancer screening program in Southern Brazil].

    PubMed

    Ribeiro, Rodrigo Antonini; Caleffi, Maira; Polanczyk, Carisi Anne

    2013-11-01

    The aim of this study was to evaluate the cost-effectiveness of an organized breast cancer mammographic screening program implemented in Porto Alegre (Núcleo Mama Porto Alegre - NMPOA), Rio Grande do Sul State, Brazil. A Markov model was constructed to estimate the incremental cost-effectiveness ratio of NMPOA compared to current BC diagnosis and care in the Brazilian public health system, in a hypothetical cohort of women aged 40-69 years at risk of developing breast cancer. Model parameters were collected from NMPOA and the national literature. In the NMPOA strategy, effectiveness was modeled taking into account the actual observed screening adherence. Effectiveness was measured in quality-adjusted life years (QALYs). Incremental cost-effectiveness ratio in the base case was R$ 13,426 per QALY. This result was not sensitive to variation in the main model parameters in sensitivity analyses. Considering the threshold usually suggested as highly attractive in Brazil, breast cancer screening as performed in NMPOA is cost-effective in cities with high incidence of breast cancer. PMID:25402242

  6. Modelos de Simulacin Estocstica: Simulando la Aleatoriedad

    E-print Network

    Figueira, Santiago

    ;Modelos de Simulación- 3 I. Modelado de sistemas mediante simulación TRATAMIENTO DEL TIEMPO RELOJ DE cuenta instantes exactos (no error) 0 s1 s2 s3 #12;Modelos de Simulación- 5 I. Modelado de sistemas PROGRAMACI�N Ejecutar y comparar con modelo 5. VALIDAR EL MODELO Ejecutar y comparar con sistema o solución

  7. Capacitación del personal y de los pacientes en torno a los cuidados terminales

    Cancer.gov

    Al no abordar el tema de la transición de un tratamiento activo para el cáncer a los cuidados en la etapa final de la vida, los médicos pueden desconocer lo que un paciente realmente desea y esto puede ser motivo de angustia para pacientes y familiares. Los investigadores han diseñado programas innovadores para ayudar a médicos y pacientes a mejorar sus habilidades de comunicación y a sentirse más cómodos al hablar de este tema.

  8. Revista "Computacion y Sistemas", Vol. 8, No. 4, June 2005 Segmentacion de imagenes en color utilizando

    E-print Network

    Angulo,Jesús

    Revista "Computaci´on y Sistemas", Vol. 8, No. 4, June 2005 Segmentaci´on de im´agenes en color) recientemente propuesta (mejorando al sistema HLS), y que tienen caracter´isticas apropiadas para el tratamiento informaci´on de intensidad o/y la informaci´on espacial. Para las im´agenes a nivel de gris, una de las t

  9. Part 13, Authors: R To Rzoska 

    E-print Network

    Humphrey, Judith M.; Ray, Doris H.; Hassall, Albert; Doss, Mildred A.

    1951-01-01

    ' ''''- ismit?i- :?. ?;.! ?.'' . . - ?? i?H>iii4 ???*??*?|8.?m] '..-i - ria ' ? ? ??! ?> !?> ???1 ?? IfcfcsS ^"t..., London (3290), v. 130, Nov. 19, pp. 784- 785. [W*.] R., L.1 1935 a.?Tratamiento de la amibiasis intestinal

  10. Programa de formación en Psico-Oncología para residentes de Psiquiatría y Psicología Clínica: modelo de interconsulta

    Microsoft Academic Search

    María Francisca Hollenstein Prat; Jorge Maté Méndez; Francisco Luis Gil Moncayo

    2003-01-01

    Resumen  La formación en Psico-Oncología tiene como objetivo principal dotar al residente de Psicología Clínica y Psiquiatría de los\\u000a conocimientos teórico-prácticos y de las habilidades clínicas necesarias para la evaluación, el diagnóstico y el tratamiento\\u000a psicológico de las reacciones emocionales y de los trastornos psicopatológicos presentes en el paciente con cáncer y sus familiares,\\u000a así como la adquisición de habilidades y

  11. El Centro para la Salud Mundial del NCI anuncia las primeras becas de investigación para apoyar las tecnologías portátiles

    Cancer.gov

    El Centro para la Salud Mundial del NCI (CGH) anunció el otorgamiento de subvenciones que apoyarán el desarrollo y la validación de tecnologías portátiles y de bajo costo. Estas tecnologías tienen el potencial de mejorar la detección temprana, el diagnóstico y los tratamientos no invasivos o mínimamente invasivos de varios tipos de cáncer con una prevalencia particularmente alta en ciertos países con economías de ingreso bajo y mediano.

  12. Gravitational tidal effects on galactic open clusters

    NASA Astrophysics Data System (ADS)

    Bergond, G.; Leon, S.; Guibert, J.

    2001-10-01

    We have investigated the 2-D stellar distribution in the outer parts of three nearby open clusters: NGC 2287 (equiv M 41), NGC 2516, and NGC 2548 (equiv M 48). Wide-field star counts have been performed in two colours on pairs of digitized ESO and SRC Schmidt plates, allowing us to select likely cluster members in the colour-magnitude diagrams. Cluster tidal extensions were emphasized using a wavelet transform. Taking into account observational biases, namely the galaxy clustering and differential extinction in the Galaxy, we have associated these stellar overdensities with real open cluster structures stretched by the galactic gravitational field. As predicted by theory and simulations, and despite observational limitations, we detected a general elongated (prolate) shape in a direction parallel to the galactic Plane, combined with tidal tails extended perpendicularly to it. This geometry is due both to the static galactic tidal field and the heating up of the stellar system when crossing the Disk. The time varying tidal field will deeply affect the cluster dynamical evolution, and we emphasize the importance of adiabatic heating during the Disk-shocking. In the case of NGC 2548, our dating of the last shocking with the Plane (based on a tidal clump) is consistent with its velocity. During the 10-20 Z-oscillations experienced by a cluster before its dissolution in the Galaxy, crossings through the galactic Disk contribute to at least 15% of the total mass loss. Using recent age estimations published for open clusters, we find a destruction time-scale of about 600 Myr for clusters in the solar neighbourhood. Plate scanning was done at the Centre d'Analyse des Images (CAI) with M.A.M.A. (Machine Automatique àMesurer pour l'Astronomie), a facility located at the Observatoire de Paris, developed and operated by INSU (Institut National des Sciences de l'Univers, CNRS). Web site http://dsmama.obspm.fr

  13. Histological mechanisms of the resistance conferred by the Ma gene against Meloidogyne incognita in Prunus spp.

    PubMed

    Khallouk, Samira; Voisin, Roger; Van Ghelder, Cyril; Engler, Gilbert; Amiri, Saïd; Esmenjaud, Daniel

    2011-08-01

    The Ma gene from Myrobalan plum is a TNL gene that confers a high-level resistance to all root-knot nematodes of major economic importance, including Meloidogyne incognita, M. javanica, M. arenaria, and M. enterolobii. The nematode behavior in the roots and the corresponding histological mechanisms of the Ma resistance to M. incognita in the resistant (R) accessions of the plum 'P.2175' and the interspecific hybrid P.2175×almond-peach '35', carrying the Ma1 allele (Ma1/ma), were characterized in comparison with the susceptible (S) accessions in the plum 'P.2032' and the interspecific hybrid P.2175×almond-peach '253' (ma/ma). Second-stage juveniles (J2s) were inoculated in micropropagated plantlets grown in soil substrate under controlled conditions at 25°C. Nematodes penetrated both R and S plants preferentially along the apical zone or close to the young lateral buds and moved via similar routes. Then they migrated into the cortex downward in the direction of the apex and turned up in the meristematic apical region to colonize the differentiating stele. In R accessions, motile J2s neither swelled nor developed into J3s, and initiation of feeding sites was never observed. This complete absence of gall symptoms is associated with cell necroses and corresponding hypersensitive-like reaction (HLR) phenotypes occurring either in the stele or in the meristematic apical region or in the cortex. Nematode attacks often disorganized the meristematic apical tissues of R accessions, which induced the development of subterminal lateral roots replacing primary terminal apices and, thus, provided an active resistance reaction to HLR damage. PMID:21446787

  14. Background and Scattered Light Subtraction in the High-Resolution Echelle Modes of the Space Telescope Imaging Spectrograph

    E-print Network

    J. Christopher Howk; Kenneth R. Sembach

    1999-12-17

    We present a simple, effective approach for estimating the on-order backgrounds of spectra taken with the highest-resolution modes of the Space Telescope Imaging Spectrograph (STIS) on-board the Hubble Space Telescope. Our scheme for determining the on-order background spectrum uses polynomial fits to the inter-order scattered light visible in the two-dimensional STIS MAMA images. We present a suite of high-resolution STIS spectra to demonstrate that our background subtraction routine produces the correct overall zero point, as judged by the small residual flux levels in the centers of strongly-saturated interstellar absorption lines. Although there are multiple sources of background light in STIS echelle mode data, this simple approach works very well for wavelengths longward of Lyman-alpha. At shorter wavelengths, the smaller order separation and generally lower signal-to-noise ratios of the data can reduce the effectiveness of our background estimation procedure. Slight artifacts in the background-subtracted spectrum can be seen in some cases, particularly at wavelengths <1300 Ang. Most of these are caused by echelle scattering of strong spectral features into the inter-order light. We discuss the limitations of high-resolution STIS data in light of the uncertainties associated with our background subtraction procedure. We compare our background-subtracted STIS spectra with GHRS Ech-A observations of the DA white dwarf G191-B2B and GHRS first-order G160M observations of the early-type star HD 218915. We find no significant differences between the GHRS data and the STIS data reduced with our method in either case.

  15. Detrimental Impact of Remote Methamphetamine Dependence on Neurocognitive and Everyday Functioning in Older but not Younger HIV+ Adults: Evidence for a Legacy Effect?

    PubMed Central

    Iudicello, Jennifer E.; Morgan, Erin E.; Gongvatana, Assawin; Letendre, Scott L.; Grant, Igor; Woods, Steven Paul

    2014-01-01

    Prior studies examining the combined adverse effects of HIV and methamphetamine (MA) on the central nervous system (CNS) have focused on younger to middle-aged adults with recent MA use diagnoses. Aging, HIV, and MA all converge on prefrontal and temporolimbic neural systems and confer independent risk for neurocognitive and functional decline. Thus, this study sought to determine the residual impact of a remote history of MA dependence on neurocognitive and real-world outcomes in older people living with HIV (PLWH). Participants included 116 older (?50 years) and 94 younger (<40 years) adults classified into one of six study groups based on HIV serostatus (HIV+/HIV-) and lifetime histories of MA dependence (MA+/MA-): Older HIV-MA- (n=36), Older HIV+MA- (n=49), Older HIV+MA+ (n=31), Younger HIV-MA- (n=27), Younger HIV+MA- (n=33), and Younger HIV+MA+ (n=34). No participant met criteria for current MA use disorders and histories of MA dependence were remote in both the Older (average of nearly 9 years prior to evaluation) and Younger (average of over 2 years prior to evaluation) HIV+MA+ groups. Findings revealed that a remote history of MA dependence exerts a significant detrimental impact on specific aspects of neurocognitive performance (e.g., memory) and a broad range of real-world functioning outcomes (e.g., employment) among Older, but not Younger PLWH. These results suggest that MA-associated neurotoxicity may have significant “legacy” effects on both neurocognitive and functional outcomes to which older PLWH are particularly vulnerable. PMID:24470237

  16. Spatially resolved UV spectra of Io's Prometheus Plume and anti-Jovian hemisphere

    NASA Astrophysics Data System (ADS)

    Jessup, K. L.; Spencer, J.; Ballester, G. E.; Yelle, R.; Roessler, F.; Howell, R.

    2002-09-01

    We present the highest spatial resolution UV spectroscopy of Io's atmosphere yet obtained. Observing Io's anti-jovian hemisphere with the 0.1" wide slit of the HST Space Telescope Imaging Spectrograph (STIS), the G230L grating and the NUV-MAMA centered on the Prometheus plume, we covered latitudes from 60 N to 60 S including the volcanos Zamama, Malik, Tupan, and Chaac, as well as SO2 frost plains. We will report the SO and SO2 column densities and SO2 gas temperatures observed in each region. Surprisingly, there is only a modest difference in SO2 column abundance between the Prometheus plume and nearby low-latitude SO2 frost plains. Additionally, continuum emission is observed over the Prometheus plume and neighboring low latitude regions near 2800 Å. Preliminary analysis indicates that the intensity of these emissions is consistent with that reported by Geissler et al. (1999) for the emissions,assumed to be continuum emission from SO2, observed over the Prometheus plume by Galileo at 4100 Å. Our model for SO2 gas absorption is based on the most recent SO2 absorption cross-section data. This includes the high resolution (5-7 mA FWHM) Rufus et al. (2001) data taken at 159 K which extends from 1980 to 2200 A, and the 295 K Stark et al. (1999) and Smith et al. (2001) data which has the same resolution as the former and extends from 1980 to 3200 A. The low resolution (0.5 A) 200 K Wu et al. (2000) data which extends from 1980 to 2970 A is also utilized. This model represents the most accurate model of the SO2 gas absorption cross-section possible within the limits of the available SO2 laboratory data.

  17. Chemical composition of basement fluids within an oceanic ridge flank: Implications for along-strike and across-strike hydrothermal circulation

    NASA Astrophysics Data System (ADS)

    Wheat, C. Geoffrey; Elderfield, Henry; Mottl, Michael J.; Monnin, Christophe

    2000-06-01

    Compositions of basement fluids are presented for four sites along a 3.5-m.y.- old, partly buried basement ridge on the eastern flank of the Juan de Fuca Ridge. This ridge is roughly parallel to the active ridge axis of the Endeavor Segment ˜100 km to the west. From south to north these sites are Baby Bare Outcrop, Ocean Drilling Program (ODP) Site 1026, and the southern and northern sides of Mama Bare Outcrop. The composition of basement fluids is determined or estimated from analyses of pore water samples that were extracted from sediments at each of these sites, spring waters from Baby Bare, and basement fluids that vented from the open ODP Hole 1026B. Chemical trends in basement fluids along this transect show increasing alteration from south to north. A similar trend was observed along an ODP transect perpendicular to the ridge axis with increasing fluid alteration from west to east. Much of the increase in fluid alteration along the ODP transect is explained by greater water-rock exchange with increasing basement temperature to the east. In contrast, the trend along the 3.5-m.y.-old ridge is best explained by diffusive exchange with the overlying sediment. The rate of this exchange is used to constrain hydrologie properties within basaltic basement. Flow within the 3.5-m.y.-old ridge is inferred to occur from south to north and lacks significant exchange with basement fluids from the active ridge crest to the west. Thus the two flow systems are hydrologically distinct, and flow paths are likely influenced by the complex distribution of permeability in basement, the pattern of seafloor morphology, and the type and rate of sedimentation.

  18. Sensitivity Monitor Report for the STIS First-Order Modes

    NASA Astrophysics Data System (ADS)

    Walborn, Nolan R.; Bohlin, Ralph C.

    1998-10-01

    The sensitivity of the STIS first-order CCD and MAMA modes has been monitored by observations of standard stars for over a year, from shortly after their initial turnon near mid-1997 until the present. The bulk of the data are from the L modes, although some observations in the M modes provide useful complementary information. Examples of the data in each mode are illustrated, providing an overview of the STIS first-order capabilities. Any changes in the average CCD sensitivities are less than 1%/yr. The formal slope of the fit to the monitoring data and 1 s uncertainties are G230LB: +0.56 %/yr ± 0.29, G430L: -0.07 %/yr ± 0.27, G750L: +0.19 %/yr ±0.43. A small but significant dependence of the G140L sensitivity on temperature, of -0.37%/deg C ± 0.06, has been found. After the observations are corrected for that effect, the G140L sensitivity changes are also less than 1%/yr (0.77 ± 0.33). The G230L sensitivity is observed to INCREASE at a rate of +1.6%/yr (8 s) over the entire wavelength range, and by 2.2%/yr (6 s) in the 2200-2400 Å range. Hence, no significant losses of sensitivity due to contamination or any other cause have been observed during this period. After correcting G140L and G230L for temperature and time correlations, respectively, the 1 s photometric repeatabilities in broad bands range from 0.3% for G230L to 0.7% for G750L.

  19. Hospital-based surveillance of malaria-related paediatric morbidity and mortality in Kinshasa, Zaire.

    PubMed Central

    Greenberg, A. E.; Ntumbanzondo, M.; Ntula, N.; Mawa, L.; Howell, J.; Davachi, F.

    1989-01-01

    Although Plasmodium falciparum malaria is a leading cause of paediatric morbidity and mortality in Africa, few quantitative estimates are available about the impact of malaria on childhood health. To quantify the impact of the disease in an urban African setting, we reviewed the paediatric ward and mortuary records at Mama Yemo Hospital in Kinshasa, Zaire. From June 1985 to May 1986, 6208 children were admitted to the hospital, 2374 (38.2%) of whom had malaria; 500 of those with malaria died (case fatality rate, 21.1%). During this same period, there were 10,036 paediatric deaths, 1323 (13.2%) of which were attributed to malaria; 823 (62.2%) of these occurred in the emergency ward prior to hospitalization. Minimum population-based malaria mortality rates were highest for children aged less than 1 year (4.0 per 1000 per year). Over 70% of children admitted with malaria and greater than 80% of children who died from the disease were less than 5 years old. The total number of paediatric admissions and deaths remained relatively constant between 1982 and 1986; however, the proportional malaria admission rate increased from 29.5% in 1983 to 56.4% in 1986, and the proportional malaria mortality rate, from 4.8% in 1982 to 15.3% in 1986. These increases were temporally related to the emergence of chloroquine-resistant Plasmodium falciparum malaria in Kinshasa. Malaria is therefore a major cause of paediatric morbidity and mortality in the city, and this study indicates that hospital-based surveillance may be useful in monitoring disease-specific morbidity and mortality elsewhere in Africa. PMID:2743538

  20. Fabrication of Thiol-Ene "Clickable" Copolymer-Brush Nanostructures on Polymeric Substrates via Extreme Ultraviolet Interference Lithography.

    PubMed

    Dübner, Matthias; Gevrek, Tugce N; Sanyal, Amitav; Spencer, Nicholas D; Padeste, Celestino

    2015-06-01

    We demonstrate a new approach to grafting thiol-reactive nanopatterned copolymer-brush structures on polymeric substrates by means of extreme ultraviolet (EUV) interference lithography. The copolymer brushes were designed to contain maleimide functional groups as thiol-reactive centers. Fluoropolymer films were exposed to EUV radiation at the X-ray interference lithography beamline (XIL-II) at the Swiss Light Source, in order to create radical patterns on their surfaces. The radicals served as initiators for the copolymerization of thiol-ene "clickable" brushes, composed of a furan-protected maleimide monomer (FuMaMA) and different methacrylates, namely, methyl methacrylate (MMA), ethylene glycol methyl ether methacrylate (EGMA), or poly(ethylene glycol) methyl ether methacrylate (PEGMA). Copolymerization with ethylene-glycol-containing monomers provides antibiofouling properties to these surfaces. The number of reactive centers on the grafted brush structures can be tailored by varying the monomer ratios in the feed. Grafted copolymers were characterized by using attenuated total reflection infrared (ATR-IR) spectroscopy. The reactive maleimide methacrylate (MaMA) units were utilized to conjugate thiol-containing moieties using the nucleophilic Michael-addition reaction, which proceeds at room temperature without the need for any metal-based catalyst. Using this approach, a variety of functionalities was introduced to yield polyelectrolytes, as well as fluorescent and light-responsive polymer-brush structures. Functionalization of the brush structures was demonstrated via ATR-IR and UV-vis spectroscopy and fluorescence microscopy, and was also indicated by a color switch. Furthermore, grafted surfaces were generated via plasma activation, showing a strongly increased wettability for polyelectrolytes and a reversible switch in static water contact angle (CA) of up to 18° for P(EGMA-co-MaMA-SP) brushes, upon exposure to alternating visible and UV-light irradiation. PMID:25978723

  1. Optimised Post-Exposure Image Sharpening Code for L3-CCD Detectors

    SciTech Connect

    Harding, Leon K.; Butler, Raymond F.; Redfern, R. Michael; Sheehan, Brendan J.; McDonald, James [Centre for Astronomy, National University of Ireland-Galway, University Road, Galway (Ireland)

    2008-02-22

    As light from celestial bodies traverses Earth's atmosphere, the wavefronts are distorted by atmospheric turbulence, thereby lowering the angular resolution of ground-based imaging. Rapid time-series imaging enables Post-Exposure Image Sharpening (PEIS) techniques, which employ shift-and-add frame registration to remove the tip-tilt component of the wavefront error--as well as telescope wobble, thus benefiting all observations. Further resolution gains are possible by selecting only frames with the best instantaneous seeing--a technique sometimes calling 'Lucky Imaging'. We implemented these techniques in the 1990s, with the TRIFFID imaging photon-counting camera, and its associated data reduction software. The software was originally written for time-tagged photon-list data formats, recorded by detectors such as the MAMA. This paper describes our deep re-structuring of the software to handle the 2-d FITS images produced by Low Light Level CCD (L3-CCD) cameras, which have sufficient time-series resolution (>30 Hz) for PEIS. As before, our code can perform straight frame co-addition, use composite reference stars, perform PEIS under several different algorithms to determine the tip/tilt shifts, store 'quality' and shift information for each frame, perform frame selection, and generate exposure-maps for photometric correction. In addition, new code modules apply all 'static' calibrations (bias subtraction, dark subtraction and flat-fielding) to the frames immediately prior to the other algorithms. A unique feature of our PEIS/Lucky Imaging code is the use of bidirectional wiener-filtering. Coupled with the far higher sensitivity of the L3-CCD over the previous TRIFFID detectors, much fainter reference stars and much narrower time windows can be used.

  2. Detection of specific UL49 sequences of Marek's disease virus CVI988/Rispens strain using loop-mediated isothermal amplification.

    PubMed

    Wo?niakowski, Grzegorz; Niczyporuk, Jowita Samanta

    2015-09-01

    Marek's disease (MD) is a tumoral disease of chickens that can be controlled by vaccines based on non-pathogenic strains of turkey herpesvirus (HVT), SB-1 strain belonging to serotype 2, or the attenuated CVI988/Rispens strain belonging to serotype 1 of Marek's disease virus (MDV). Currently, the 'gold standard' in MD prophylaxis is the Rispens strain-based vaccine which protects against very virulent MDV and disease onset. Previous studies have shown that loop-mediated isothermal amplification (LAMP) is a rapid alternative to polymerase chain reaction (PCR) for detection and differentiation of HVT, SB-1 and virulent MDV strains. The aim of this study was to develop and evaluate a novel LAMP assay for the detection of the UL49 Rispens-specific region. This assay was validated using material from infected chicken embryo fibroblasts (CEFs) and tissue samples from vaccinated chickens. The analytical sensitivity of the assay was 10-times higher than PCR and reliably amplified 0.1 log10 TCID50/ml. The MDV Rispens was also detected at 18h after infection of CEFs. The results showed LAMP to be selective and a sensitive method to detect Rispens as early as 3 d.p.v. in all internal organs of chickens. Furthermore, the method was also capable to detect Rispens in 5 out of 26 chickens originating from different flocks. A mismatch amplification mutation assay (MAMA-PCR) confirmed the presence of Rispens strain in all LAMP-positive chickens. This is the first report of the specific visual detection of Rispens in vitro and in vivo using LAMP. The method may be useful for monitoring of successful chicken vaccination as well as in vitro studies in infected cell cultures. PMID:25920566

  3. Overlapping gene coexpression patterns in human medullary thymic epithelial cells generate self-antigen diversity

    PubMed Central

    Pinto, Sheena; Michel, Chloé; Schmidt-Glenewinkel, Hannah; Harder, Nathalie; Rohr, Karl; Wild, Stefan; Brors, Benedikt; Kyewski, Bruno

    2013-01-01

    Promiscuous expression of numerous tissue-restricted self-antigens (TRAs) in medullary thymic epithelial cells (mTECs) is essential to safeguard self-tolerance. A distinct feature of promiscuous gene expression is its mosaic pattern (i.e., at a given time, each self-antigen is expressed only in 1–3% of mTECs). How this mosaic pattern is generated at the single-cell level is currently not understood. Here, we show that subsets of human mTECs expressing a particular TRA coexpress distinct sets of genes. We identified three coexpression groups comprising overlapping and complementary gene sets, which preferentially mapped to certain chromosomes and intrachromosomal gene clusters. Coexpressed gene loci tended to colocalize to the same nuclear subdomain. The TRA subsets aligned along progressive differentiation stages within the mature mTEC subset and, in vitro, interconverted along this sequence. Our data suggest that single mTECs shift through distinct gene pools, thus scanning a sizeable fraction of the overall repertoire of promiscuously expressed self-antigens. These findings have implications for the temporal and spatial (re)presentation of self-antigens in the medulla in the context of tolerance induction. PMID:23980163

  4. Identification of a membrane protein associated with expression of the surface exclusion region of the F transfer operon.

    PubMed Central

    Minkley, E G; Ippen-Ihler, K

    1977-01-01

    Membrane preparations from radioactively labeled male and female strains of Escherichia coli K-12 were analyzed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and autoradiography. An intensely labeled band corresponding to a protein of molecular weight of 24,000 was readily apparent in preparations from Hfr and F-prime strains but not in those from female strains. When preparations from a series of Hfr strains containing transfer operon deletions were examined, presence of the band was found to be associated with retention of the region of the F transfer operon between ilzA and traD. Thus, the band ("protein S") appears to be the product of an F tra operon activity corresponding to traS (the gene for surface or entry exclusion), or an unknown gene in its vicinity. As predicted, protein S was subject to Fin+ control; only a faint band was detectable if the repressed plasmid R100 was also present in the F lac strain. A 24,000-dalton protein was also found in membrane preparations from strains carrying the derepressed plasmids R100-1 and R1-19 but not in those from strains carrying the repressed plasmids R100 or R1. Thus, the appearance of protein S in the membrane may be a general phenomenon resulting from transfer operon expression of F-like plasmids. Images PMID:321436

  5. Central T cell tolerance: Identification of tissue-restricted autoantigens in the thymus HLA-DR peptidome.

    PubMed

    Alvarez, Iñaki; Collado, Javier A; Colobran, Roger; Carrascal, Montserrat; Ciudad, M Teresa; Canals, Françesc; James, Eddie A; Kwok, William W; Gärtner, Martina; Kyewski, Bruno; Pujol-Borrell, Ricardo; Jaraquemada, Dolores

    2015-06-01

    Promiscuous gene expression (pGE) of tissue-restricted self-antigens (TRA) in medullary thymic epithelial cells (mTECs) is in part driven by the Autoimmune Regulator gene (AIRE) and essential for self-tolerance. The link between AIRE functional mutations and multi-organ autoimmunity in human and mouse supports the role of pGE. Deep sequencing of the transcriptome revealed that mouse mTECs potentially transcribe an unprecedented range of >90% of all genes. Yet, it remains unclear to which extent these low-level transcripts are actually translated into proteins, processed and presented by thymic APCs to induce tolerance. To address this, we analyzed the HLA-DR-associated thymus peptidome. Within a large panel of peptides from abundant proteins, two TRA peptides were identified: prostate-specific semenogelin-1 (an autoantigen in autoimmune chronic prostatitis/chronic pelvic pain syndrome) and central nervous system-specific contactin-2 (an autoantigen in multiple sclerosis). Thymus expression of both genes was restricted to mTECs. SEMG1 expression was confined to mature HLA-DR(hi) mTECs of male and female donors and was AIRE-dependent, whereas CNTN2 was apparently AIRE-independent and was expressed by both populations of mTECs. Our findings establish a link between pGE, MHC-II peptide presentation and autoimmunity for bona fide human TRAs. PMID:25911201

  6. Established Thymic Epithelial Progenitor/Stem Cell-Like Cell Lines Differentiate into Mature Thymic Epithelial Cells and Support T Cell Development

    PubMed Central

    Zhan, Yu; Su, Juanjuan; Du, Yarui; Xu, Guoliang; Shi, Yufang; Siebenlist, Ulrich; Zhang, Xiaoren

    2013-01-01

    Common thymic epithelial progenitor/stem cells (TEPCs) differentiate into cortical and medullary thymic epithelial cells (TECs), which are required for the development and selection of thymocytes. Mature TEC lines have been widely established. However, the establishment of TEPC lines is rarely reported. Here we describe the establishment of thymic epithelial stomal cell lines, named TSCs, from fetal thymus. TSCs express some of the markers present on tissue progenitor/stem cells such as Sca-1. Gene expression profiling verifies the thymic identity of TSCs. RANK stimulation of these cells induces expression of autoimmune regulator (Aire) and Aire-dependent tissue-restricted antigens (TRAs) in TSCs in vitro. TSCs could be differentiated into medullary thymic epithelial cell-like cells with exogenously expressed NF-?B subunits RelB and p52. Importantly, upon transplantation under the kidney capsules of nude mice, TSCs are able to differentiate into mature TEC-like cells that can support some limited development of T cells in vivo. These findings suggest that the TSC lines we established bear some characteristics of TEPC cells and are able to differentiate into functional TEC-like cells in vitro and in vivo. The cloned TEPC-like cell lines may provide useful tools to study the differentiation of mature TEC cells from precursors. PMID:24086471

  7. Controlling the Pecan Nut Casebearer (Spanish)

    E-print Network

    Knutson, Allen E.; Ree, Bill

    2001-04-11

    ?n tendr?a por lo menos una semana de adelanto con respecto a un tratamiento m?s oportuno, o podr?a resultar totalmente innece- saria. Los estudios realizados indican que el n?mero de palomillas capturadas refleja con precisi?n la activi- dad de las...?as y lluviosas, ya que esto puede retrasar la oviposici?n. Si durante este muestreo encuentra menos de tres racimos infestados no se justi- fica la aspersi?n. Cuando en este momento se tienen infestaciones de tres o m?s racimos esto indica que podr...

  8. Drinking Water Problems: Perchlorate (Spanish) 

    E-print Network

    Dozier, Monty; Melton, Rebecca; Hare, Michael; Porter, Dana; Lesikar, Bruce J.

    2006-02-21

    calificado para determinar la calidad del agua. Una lista de laboratorios certificados por la Comisi?n Tejana para la Calidad Ambiental (TCEQ por sus siglas en ingl?s) para realizar pruebas al agua potable puede encontrarse en: http://www.tnrcc.state. tx.us... y perju- dicar la calidad del agua tratada. El agua que sale de las unidades de tratamiento debe de ser examinada regularmente para verificar el funcionamiento apropiado del sistema. 4 Fuentes Burge, S., and Halde, R. 1999. Nitrate and Perchlorate...

  9. On-Site Wastewater Treatment Systems: Constructed Wetlands (Spanish)

    E-print Network

    Lesikar, Bruce J.; Enciso, Juan

    2002-04-18

    ?n, cloruro de polivinilo, ?Hypalon? o hule ?PondGard? de terpol?mero de etileno-propileno y dieno (EPDM). El lecho en s? es normalmente de grava pero puede ser de cualquier material poroso que no se corroe o disuelva con las aguas negras. El lecho de medio... acu?ticas. Quita nutrientes, materia org?nica, s?lidos en suspensi?n y pat?genos. a19 Un sistema de aplicaci?n en suelo. Dispersa las aguas negras en la tierra para el tratamiento y disposici?n final o reutilizaci?n. Los sistemas de humedal artifi...

  10. La mujer y el amor en El mismo mar de todos los veranos, de Esther Tusquets 

    E-print Network

    Reed, Linnette Fourquet

    1985-01-01

    . Al fin y al cabo es esta la base del fsnunismo en cualquier sociedad. Es claro que en los textos de estas escritoras no se nos presentan criticas abiertas a la sociedad sexista es- panola, imposible hacerlo en una sociedad de tipo represivo, pero... no publicaba en Espana desde los ahos sesenta y por lo tanto no teru. a que pasar por los avatares de la censura. De todas maneras, lo que es claro en ambos, con el tratamiento de estos temas tabues, es el deseo de rrastrar un rechazo de las que eran...

  11. Mosquito Control Around the Home (Spanish) 

    E-print Network

    Jackman, John A.; Olson, Jimmy K.

    2003-03-17

    a73 Usar repelentes cuando se visite cualquierlocalidad infestada por mosquitos . Productos que contienen DEET han mostra-do ser los repelentes m?s confiables . a73 P ara alivio temporal en patios o ?reas de descanso o picnic , usar candelas o...?ticospueden ser afectados por tratamientos conaceites .Contr ol a largo plazo P ara un control efectiv o y a largo plazo se requiere el uso de v arias t?cnicas de manejo. El control de mosquitos es usualmente com-plejo y costoso, y requiere de la cooperaci...

  12. Identificación de los miembros del cúmulo NGC 2516

    NASA Astrophysics Data System (ADS)

    de Elía, G. C.; Orellana, R. B.

    El cúmulo abierto NGC 2516 (? = 7h 58m y ? = -60o 45') tiene una edad de, aproximadamente, 150 Myr. El análisis de este sistema es particularmente importante en el Hemisferio Sur debido a su abundancia de estrellas peculiares y muy estudiado aplicando técnicas fotométricas, pero muy poco analizado desde el punto de vista astrométrico. A partir de una placa obtenida en el Observatorio Astronómico de La Plata y observaciones más actuales, nos hemos abocado al estudio de los movimientos propios de este cúmulo con el fin de determinar la pertenencia al mismo de las estrellas del campo de dicho cúmulo. Luego de llevar a cabo la determinación de los movimientos propios de todas las estrellas a partir de las posiciones obtenidas de la placa existente en el Observatorio de La Plata de 1914 y leídas con la MAMA en París, las observaciones realizadas con el círculo meridiano de San Fernando que se encuentra en el Observatorio Félix Aguilar de San Juan y las posiciones existentes en los catálogos AC 2000, Tycho, USNO y UCAC, programamos el método de Vasilevsky y Sanders para determinar la pertenencia de las estrellas de la región al cúmulo en cuestión. En un paso posterior, se realizó una modificación al método anterior para la determinación de los miembros. En esta modificación se consideró la densidad de las estrellas del cúmulo y la densidad de estrellas de campo. Esto permitió evaluar la pertenencia, no sólo a partir del movimiento propio de las estrellas, sino también a partir de la posición de las mismas con respecto al centro del cúmulo. También se consideró la dependencia de los parámetros con la magnitud. Los resultados así obtenidos fueron comparados con otras investigaciones de movimientos propios de la región del cúmulo. El movimiento propio absoluto del cúmulo fue comparado con el obtenido a partir de los catálogos estelares. Se encontró que los resultados coincidían para estrellas brillantes (magnitud más brillante que 12.0 aproximadamente) y que no coincidían para estrellas más débiles. La tarea que llevamos a cabo en estos momentos está referida a encontrar la causa de tales discrepancias con el fin de obtener los mejores resultados.

  13. Ancestral irrigation method by kanis in Bolivia

    NASA Astrophysics Data System (ADS)

    Roldán-Cañas, José; Chipana, René; Fátima Moreno-Pérez, María

    2015-04-01

    Irrigation in the Andean region is an ancient practice. For centuries, farmers were able to use the waters of rivers, lakes and springs to complement or supplement the scarce rainfall regime. The inter-Andean valleys of the Department of La Paz are the best areas for the study of traditional irrigation systems. This work has been carried out in the community of Jatichulaya located in te town of Charazani, 300 km from the city of La Paz, which lies 3250 meters above sea level. The annual rainfall ranges around 450 mm distributed mainly between the months of December to March. Therefore, water is needed to achieve adequate crop yields. The traditional irrigation system is done by the method of Kanis, consisting of a surface irrigation already developed by traditional Andean cultures of the country, in harmony with the ecological and productive characteristics of the area. Water enters the irrigation plot through a main channel (mama kani) from which the secondary channels (juchuy kanis) are derived. The fundamental characteristic of this irrigation is that these channels are open at the same time the water enters into the plot. The system works properly, adapting to the topography of the area. The irrigation method practiced in this community does not cause water erosion of soils because water management within the plot is based on the ancient knowledge of farmers following the contour lines. This practice allows good irrigation development and soil protection without causing any problems. However, it was evident a high use of labor in irrigation practice. Irrigation scheduling is done according to requests made by the irrigators in a given period. Delivering of water to the farmers is made by the so-called Water Agent (Agente de Aguas) or person in charge of the distribution of water. The Water Agent is elected annually and its functions include the maintenance and care of all system waterworks. The period between August and January is the highest water demand and, therefore, the water is distributed by turns among irrigators. Turns usually depend on water availability. Water Agent distributes water equitably without giving preference to anyone.

  14. Trends in antenatal care attendance and health facility delivery following community and health facility systems strengthening interventions in Northern Uganda

    PubMed Central

    2013-01-01

    Background Maternal morbidity and mortality remains high in Uganda; largely due to inadequate antenatal care (ANC), low skilled deliveries and poor quality of other maternal health services. In order to address both the demand and quality of ANC and skilled deliveries, we introduced community mobilization and health facility capacity strengthening interventions. Methods Interventions were introduced between January 2010 and September 2011. These included: training health workers, provision of medical supplies, community mobilization using village health teams, music dance and drama groups and male partner access clubs. These activities were implemented at Kitgum Matidi health center III and its catchment area. Routinely collected health facility data on selected outcomes in the year preceding the interventions and after 21 months of implementation of the interventions was reviewed. Trend analysis was performed using excel and statistical significance testing was performed using EPINFO StatCal option. Results The number of pregnant women attending the first ANC visit significantly increased from 114 to 150 in the first and fourth quarter of 2010 (OR 1.72; 95% CI 1.39–2.12) and to 202 in the third quarter of 2011(OR 11.41; 95% CI 7.97–16.34). The number of pregnant women counselled, tested and given results for HIV during the first ANC attendance significantly rose from 92 (80.7%) to 146 (97.3%) in the first and fourth quarter of 2010 and then to 201 (99.5%) in the third quarter of 2011. The number of male partners counseled, tested and given results together with their wives at first ANC visit rose from 13 (16.7%) in the fourth quarter of 2009 to 130 (89%) in the fourth quarter of 2010 and to 180 (89.6%) in the third quarter of 2011. There was a significant rise in the number of pregnant women delivering in the health facility with provision of mama-kits (delivery kits), from 74 (55.2%) to 149 (99.3%) in the second and fourth quarter of 2010. Conclusions Combined community and facility systems strengthening interventions led to increased first ANC visits by women and their partners, and health facility deliveries. Interventions aimed at increasing uptake of maternal health services should address both the demand and availability of quality services. PMID:24134717

  15. Polystyrene grafting from silica nanoparticles via Nitroxide-Mediated-Polymerization (NMP): synthesis and SANS analysis with contrast variation method

    E-print Network

    Chloé Chevigny; Didier Gigmes; Denis Bertin; Jacques Jestin; François Boué

    2010-05-10

    We present a new convenient and efficient "grafting from" method to obtain well defined polystyrene (PS) silica nanoparticles. The method, based on Nitroxide-Mediated Polymerization (NMP), consists to bind covalently the alkoxyamine, which acts as initiator controller agent, at the silica nanoparticles surface in two steps. The first step is a reaction between the aminopropylsilane and the silica particles in order to functionalize the particles surface with amino group. In a second step, the initiating-controlling alkoxyamine moiety is introduced via an over grafting reaction between the amino group and the N-hydroxysuccinimide based MAMA-SG1 activated ester. To simplify both their chemical transformation and the polymerization step, the native silica particles, initially dispersed in water, have been transferred in an organic solvent, the dimethylacetamide, which is also a good solvent for the polystyrene. The synthesis parameters have been optimized for grafting density, conversion rates, and synthesis reproducibility while keeping the colloidal stability and to avoid any aggregation of silica particles induced by the inter-particles interaction evolution during the synthesis. After synthesis, the final grafted objects have been purified and the non-grafted polymer chains formed in the solvent have been washed out by ultra filtration. Then the particles have been studied using Small angle Neutron Scattering (SANS) coupled to neutron contrast variation method. To optimize the contrast conditions, both hydrogenated and deuterated monomers have been used for the synthesis. A refined fitting analysis based on the comparison on two models, a basic core-shell and the Gaussian Pedersen model, enables us to fit nicely the experimental data for both the hydrogenated and deuterated grafted case. Differences are seen between grafting of normal or deuterated chains which can be due to monomer reactivity or to neutron contrast effect variations. The synthesis and the characterization method established in this work constitute a robust and reproducible way to design well defined grafted polymer nanoparticles. These objects will be incorporated in polymer matrices in a further step to create Nanocomposites for polymer reinforcement.

  16. The Role of HIV-Related Stigma in Utilization of Skilled Childbirth Services in Rural Kenya: A Prospective Mixed-Methods Study

    PubMed Central

    Turan, Janet M.; Hatcher, Abigail H.; Medema-Wijnveen, José; Onono, Maricianah; Miller, Suellen; Bukusi, Elizabeth A.; Turan, Bulent; Cohen, Craig R.

    2012-01-01

    Background Childbirth with a skilled attendant is crucial for preventing maternal mortality and is an important opportunity for prevention of mother-to-child transmission of HIV. The Maternity in Migori and AIDS Stigma Study (MAMAS Study) is a prospective mixed-methods investigation conducted in a high HIV prevalence area in rural Kenya, in which we examined the role of women's perceptions of HIV-related stigma during pregnancy in their subsequent utilization of maternity services. Methods and Findings From 2007–2009, 1,777 pregnant women with unknown HIV status completed an interviewer-administered questionnaire assessing their perceptions of HIV-related stigma before being offered HIV testing during their first antenatal care visit. After the visit, a sub-sample of women was selected for follow-up (all women who tested HIV-positive or were not tested for HIV, and a random sample of HIV-negative women, n?=?598); 411 (69%) were located and completed another questionnaire postpartum. Additional qualitative in-depth interviews with community health workers, childbearing women, and family members (n?=?48) aided our interpretation of the quantitative findings and highlighted ways in which HIV-related stigma may influence birth decisions. Qualitative data revealed that health facility birth is commonly viewed as most appropriate for women with pregnancy complications, such as HIV. Thus, women delivering at health facilities face the risk of being labeled as HIV-positive in the community. Our quantitative data revealed that women with higher perceptions of HIV-related stigma (specifically those who held negative attitudes about persons living with HIV) at baseline were subsequently less likely to deliver in a health facility with a skilled attendant, even after adjusting for other known predictors of health facility delivery (adjusted odds ratio?=?0.44, 95% CI 0.22–0.88). Conclusions Our findings point to the urgent need for interventions to reduce HIV-related stigma, not only for improving quality of life among persons living with HIV, but also for better health outcomes among all childbearing women and their families. Please see later in the article for the Editors' Summary. PMID:22927800

  17. Effect of ocean currents on the performance of a time-reversing array in shallow water

    NASA Astrophysics Data System (ADS)

    Sabra, Karim G.; Dowling, David R.

    2003-12-01

    Active acoustic time reversal may be accomplished by recording sounds with an array of transducers-a time-reversing array (TRA) or time-reversal mirror (TRM)-and then replaying the recorded and time-reversed sounds from the same array to produce back-propagating waves that converge at the location(s) of the remote sound source(s). Future active sonar and underwater communication systems suitable for use in unknown shallow ocean waters may be developed from the automatic spatial and temporal focusing properties of TRAs. However, ocean currents affect time reversal because they alter acoustic reciprocity in the environment. This paper presents a theoretical and computational investigation into how ocean currents influence TRA retrofocusing in shallow ocean environments for various array orientations. The case of TRA retrofocusing in a three-dimensional range-independent sound channel with a steady horizontal ocean current is covered here, based on a normal-mode propagation model valid for low Mach number currents. The main finding is that in the presence of ocean currents (typically <1 m/s), a TRA performs well (the associated retrofocus amplitude decay is less than 1 dB) except that a retrofocus shift (up to a few wavelengths at 500 Hz at a range of 2.5 km) may occur due to the differing interaction between the ocean current profile and each acoustic normal mode. In addition, TRA performance is predicted to depend on the array orientation relative to the ocean current direction, especially for horizontal arrays.

  18. Effect of ocean currents on the performance of a time-reversing array in shallow water.

    PubMed

    Sabra, Karim G; Dowling, David R

    2003-12-01

    Active acoustic time reversal may be accomplished by recording sounds with an array of transducers--a time-reversing array (TRA) or time-reversal mirror (TRM)--and then replaying the recorded and time-reversed sounds from the same array to produce back-propagating waves that converge at the location(s) of the remote sound source(s). Future active sonar and underwater communication systems suitable for use in unknown shallow ocean waters may be developed from the automatic spatial and temporal focusing properties of TRAs. However, ocean currents affect time reversal because they alter acoustic reciprocity in the environment. This paper presents a theoretical and computational investigation into how ocean currents influence TRA retrofocusing in shallow ocean environments for various array orientations. The case of TRA retrofocusing in a three-dimensional range-independent sound channel with a steady horizontal ocean current is covered here, based on a normal-mode propagation model valid for low Mach number currents. The main finding is that in the presence of ocean currents (typically <1 m/s), a TRA performs well (the associated retrofocus amplitude decay is less than 1 dB) except that a retrofocus shift (up to a few wavelengths at 500 Hz at a range of 2.5 km) may occur due to the differing interaction between the ocean current profile and each acoustic normal mode. In addition, TRA performance is predicted to depend on the array orientation relative to the ocean current direction, especially for horizontal arrays. PMID:14714795

  19. Drinking Water Problems: Radionuclides (Spanish) 

    E-print Network

    Lesikar, Bruce J.; Melton, Rebecca; Hare, Michael; Hopkins, Janie; Dozier, Monty

    2006-12-21

    sistema que se va a comprar debe estar basado en el n?mero de galones que ser?n utilizados para estos prop?sitos cada d?a. Las unidades t?picas de tratamiento producen de 5 a 15 galones de agua por d?a. En caso de que se nece- siten grandes cantidades de.../gal?n = 0.024 x ???????????? x Costo de electricidad ($/k Wh) Producci?n (galones/d?a) Costos Las unidades de destilaci?n se pueden comprar a un costo de entre $300 y $1,200. Los costos de operaci?n para los sistemas de destilaci?n pueden ser m?s altos que...

  20. Drinking Water Standards (Spanish)

    E-print Network

    Dozier, Monty; McFarland, Mark L.

    2006-04-26

    tratamiento 1 (mg/l) 2 por exposici?n que supere el NMC en el agua potable Salud P?blica QIO Fl?or 4.0 Enfermedades ?seas (dolor y Aditivo para agua para promover 4.0 fragilidad ?sea) Los ni?os podr?an dientes fuertes; erosi?n de dep?sitos sufrir de dientes...- 0.05 Trastornos renales o estomacales Efluentes de f?bricas de qu?micos 0.05 ciclopentadieno QIO Plomo TT 7 ; Beb?s y ni?os: retardo en desarrollo Corrosi?n de ca?er?as en el hogar; cero Nivel de Acci?n = 0.015 f?sico o mental; los ni?os podr...

  1. Grupos españoles de cálculos ab initio de moléculas de interés astrofísico

    NASA Astrophysics Data System (ADS)

    Yáñez, M.

    Pocos campos de la química están tan bien adaptados a la modelización por medio de los métodos teóricos de la Química Cuántica como la Astroquímica y la Química de la Atmósfera, donde las interacciones moleculares son, generalmente, lo suficientemente pequeñas para que el modelo de molécula aislada funcione muy bien. En España son varios los grupos teóricos que dedican su esfuerzo de investigación, o parte de él, al estudio de moléculas o procesos de interés en Astrofísica o en atmósferas planetarias. Presentaremos diferentes ejemplos paradigmáticos de esta actividad en la que se exploran desde aspectos estructurales, hasta aspectos espectroscópicos y dinámicos. Entre los últimos, cabe destacar estudios en los que se demuestra la importancia de procesos a dos estados, prohibidos por espín, en la formación astrofísica de diversos derivados de interés. En el tratamiento espectroscópico se han hecho esfuerzos interesantes, que han aunado teoría y experimento, en el estudio de sistemas relevantes desde el punto de vista atmosférico, como los hidratos de ácido nítrico, o el tratamiento espectroscópico de moléculas no rígidas. No menos interesantes son los estudios de fotoabsorción de radicales o de procesos multifotónicos. Son particularmente abundantes los estudios dedicados a la reactividad específica de sistemas de interés astrofísico o atmosférico, con el objetivo de esclarecer vías de formación de determinados compuestos o de proporcionar mecanismos que permitan identificar las etapas reactivas limitantes de reacciones de interés en esos medios y sobre los que no existía información previa. Así, por ejemplo, se han publicado interesantes estudios sobre la formación o propiedades de compuestos de fósforo, de silico o de azufre o sobre mecanismos de reacción en los que intervienen el ozono, el radical nitrato, el radical OH u otras especies. Finalmente, son también particularmente relevantes los estudios que varios grupos españoles han llevado, y siguen llevando a cabo, sobre sistemas débilmente enlazados, como complejos de Van der Waals o complejos por enlace de hidrógeno, que sin duda juegan un papel importante tanto en medios atmosféricos como interestelares.

  2. LOOKING ALONG A FUNNEL OF LIGHT FROM A HIDDEN BLACK HOLE

    NASA Technical Reports Server (NTRS)

    2002-01-01

    In a single Hubble Space Telescope Imaging Spectrograph (STIS) CCD observation, astronomers have measured the velocities of hundreds of gas blobs caught up in a twin-cone beam of radiation emanating from a supermassive black hole at the core of galaxy NGC 4151. Further observations using STIS's Multi-Anode Microchannel Plate Array (MAMA) detectors reveal hot gas from deep within the throat of the beam, near the vicinity of the black hole, as well as unique details of absorbing clouds along our line of sight to it. Besides revealing fast-moving knots of gas in unprecedented detail, down to a resolution of four light-years (0.05 arc seconds), STIS also simultaneously measured the motions of all of blobs through the shift in the color of their light (Doppler effect) due to their motion toward or away from us. In the standard model for such an active galactic nucleus, a black hole devours gas and dust, and some of the material is converted into energy and radiated into space. The rotation of the 'central engine' also focuses radiation along two powerful and oppositely directed beams. The velocities measured by STIS show for the first time the details of its geometry and motions in the twin beam of particles and radiation coming from an active galactic nucleus: they also reveal some unexpected new puzzles at odds with the model. The inner region of compact bright knots fits the twin-cone model for the behavior of material around supermassive black holes. STIS shows that the material in the knots is moving away from the nucleus. The material lies on the inner surface of the cones rather than filling them. This means the beams illuminate the inside of the cone which has been cleared of material, perhaps by the high speed jets seen in ground-based radio pictures. Using STIS, astronomers can trace the shape and orientation of the cones, and find that the illuminated material is moving at several hundred thousand miles per hour. However, the velocities are reversed for more distant faint knots (beyond 1,000 light-years from the nucleus). This means they may have a different history, representing orbital motions of the undisturbed galaxy population, a previous epoch of different nuclear beam orientation, or some kind of backflow into the central cone regions. NGC 4151 is the brightest member of a class of galaxies called Seyferts, characterized by extraordinary energy sources in their centers. They are generally agreed to be similar to quasars, though not as bright. Because quasars are much more rare, there are none as close and as easy to study as NGC 4151. The generally accepted model for this nuclear activity is accretion by a massive black hole, hundreds of millions of times the mass of the Sun. Models predict a disk of trapped material spiraling into the hole, and jets are created along the axis of the disk, where some of the material is blasted out at high velocity rather than being captured by the black hole. The appearance of active nuclei depends how they lie with respect to our line of sight to them. If the beam is aimed at Earth astronomers can see the central 'black hole engine' directly. If the beam is sideways to the line of sight astronomers only see material illuminated by the beam. In the case of NGC 4151, Hubble is viewing along the edge of the beam.

  3. Habitus furibundo en el gueto estadounidense1

    PubMed Central

    Bourgois, Philippe; Castrillo, Fernando Montero; Hart, Laurie; Karandinos, George

    2014-01-01

    Resumen Durante cinco años, un torbellino cotidiano de tiroteos, apuñalamientos y asaltos afectó a la venta de drogas al aire libre en el vecindario puertorriqueño de Filadelfia, donde residíamos y conducíamos nuestro trabajo de campo. La industria de los narcóticos ha venido a llenar el vacío que dejó la desindustrialización, convirtiendo al antiguo distrito fabril de la ciudad en un mercado de narcóticos a cielo abierto que emplea en sus niveles más bajos a jóvenes puertorriqueños y cuyos clientes son principalmente heroinómanos blancos de bajos recursos. La capacidad para movilizar la furia asegura el éxito en la economía de las drogas, garantiza protección en las cárceles y le provee un ingreso mínimo a una población de bajos recursos estigmatizada cuyos miembros frecuentemente reciben diagnósticos médicos de discapacidad cognitiva. Muchos residentes buscan alianzas en redes sociales que los comprometen a participar en intercambios solidarios de violencia auxiliar. Una dinámica de acumulación primitiva corporizada mata, hiere, discapacita o encarcela a la mayoría de estos empleados de bajo nivel y a sus clientes. Los inflados márgenes de ganancia alrededor de esta dinámica dependen de la violencia y la coerción. Un habitus furibundo impulsa a los vendedores callejeros a defender violentamente el micro monopolio de poder de sus jefes en la economía subterránea como si fuese un asunto de diversión. Estos miembros de los niveles más bajos de la industria del narcotráfico se apresuran a fraguar transacciones comerciales en ausencia de un marco legal en un ambiente de escasez que sin embargo se ve inundado por enormes flujos de dinero, drogas adictivas y armas automáticas. Tras las drásticas reformas a los programas de seguridad social, la mano izquierda del Estado, en la forma de los servicios sociales, intenta prolongar los subsidios para individuos vulnerables diagnosticándolos como discapacitados cognitivos permanentes necesitados de fuerte medicación farmacéutica. La mejor manera de asegurar la continuidad de este frágil subsidio resulta ser los estallidos periódicos de violencia autoinfligida. Simultáneamente, con la anuencia de la mano derecha del Estado, en las cárceles violentas y hacinadas marcadas por formas hostiles de supervisión, la furia se convierte en una valiosa estrategia de protección física para los internos. En resumen, la violencia expresiva se convierte en una base práctica para el sostenimiento económico y para forjar el sentido de dignidad entre hombres y mujeres. PMID:24532976

  4. The residual and direct effects of reduced-risk and conventional miticides on twospotted spider mites, Tetranychus urticae (Acari: Tetranychidae) and predatory mites (Acari: Phytoseiidae)

    SciTech Connect

    Liburd, O.E.; White, J.C.; Rhodes, E.M. [Department of Entomology and Nematology, University of Florida, Gainesville, FL 32611 (United States); Browdy, A.A. [Department of Food Science and Human Nutrition, University of Florida, Gainesville, FL 32611 (United States)

    2007-03-15

    The residual effects of several reduced-risk and conventional miticides were evaluated in strawberries (Fragaria z ananassa Duchesne) on the twospotted spider mite (TSSM), Tetranychus urticae Koch (Acari: Tetranychidae) and on 2 predatory mites, Neoseiulus californicus McGregor and Phytoseiulus persimilis Athias-Henriot (Acari: Phytoseiidae). Experiments were conducted in the laboratory and greenhouse. The greenhouse experiments also tested the direct effects of the miticides on TSSM. The efficacy of conventional and reduced-risk miticides was evaluated on strawberry leaf discs and on whole plants for control of TSSM. Furthermore, the residual effects of these miticides were evaluated on whole strawberry plants against selective predatory mites. For TSSM, 5 treatments were evaluated: a conventional miticide; fenbutatin-oxide (Vendex[reg]) and 3 reduced-risk miticides; binfenazate (Acramite 50WP[reg]), activated garlic extract (Repel[reg]), sesame seed and castor oil (Wipeout[reg]), and a water-treated control. For predatory mites, the residual effects of only Acramite[reg] and Vendex[reg] were evaluated. Acramite[reg] was the most effective acaricide in reducing TSSM populations in both the laboratory and greenhouse experiments. Vendex[reg] and Wipeout[reg] were also effective in the laboratory, but did not cause significant reduction of TSSM in the greenhouse. Repel[reg] was the least effective of the 4 pesticides evaluated. Neither Acramite[reg] nor Vendex[reg] had a significant effect on either predatory mite species. However, there appeared to be more predatory mites on the Vendex[reg]-treated plants than on the Acramite[reg]-treated plants. There were significantly more predatory mites of both species on the cue plants, which were inoculated with TSSM versus the non-cue plants, which were not inoculated. (author) [Spanish] Los efectos residuales en poblaciones de la 'arana roja', Tetranychus urticae Koch (Acari: Tetranichidae) y de los acaros predadores Neoseiulus californicus McGregor y Phytoseilus persimilis Athias-Henriot (Acari: Phytoseiidae) causados por varios acaricidas convencionales y de riesgo-reducido fueron evaluados en fresas (Fragaria x ananassa Duchense). Los experimentos fueron realizados en laboratorio e invernadero. Los experimentos en el invernadero evaluaron tambien el efecto directo de los acaricidas en la 'arana roja'. La eficacia para controlar la 'arana roja' de los acaricidas convencionales y de riesgo-reducido fue evaluada en discos de las hojas y en plantas de fresa, y los efectos residuales de los acaricidas en los acaros predadores fueron evaluados en plantas completas. Para la 'arana roja' se evaluaron cinco tratamientos: el acaricida convencional fenbutatin-oxido (Vendex[reg]), 3 acaricidas de riesgo-reducido binfenazate (Acaramite 50WP[reg]), extracto de ajo activado (Repel[reg]), aceite de semillas de ajonjoli y ricino (Wipeout[reg]) y un control tratado con agua. Para los acaros predadores solamente los efectos de Acaramite[reg] y Vendex[reg] fueron evaluados. Acaramite[reg] fue el tratamiento mas efectivo para la 'arana roja' en el laboratorio y el invernadero. Vendex[reg] y Wipeout[reg] fueron tambien efectivos en el laboratorio, pero no causaron una reduccion significativa de 'aranas rojas' en el invernadero. Repel[reg] fue el tratamiento evaluado menos eficaz. Ni Acaramite[reg] ni Vendex[reg] redujeron significativamente las poblaciones de acaros predadores. Sin embargo, aparentemente hay mas acaros predadores en Vendex[reg] que en Acaramite[reg]. Tambien se encontraron significativamente mas acaros predadores en plantas inoculadas que en plantas no inoculadas. (author)

  5. Lessons from scaling up a depression treatment program in primary care in Chile.

    PubMed

    Araya, Ricardo; Alvarado, Rubén; Sepúlveda, Rodrigo; Rojas, Graciela

    2012-09-01

    In Chile, the National Depression Detection and Treatment Program (Programa Nacional de Diagnóstico y Tratamiento de la Depresión, PNDTD) in primary care is a rare example of an evidence-based mental health program that was scaled up to the national level in a low- or middle-income country. This retrospective qualitative study aimed to better understand how policymakers made the decision to scale up mental health services to the national level, and to explore the elements, contexts, and processes that facilitated the decision to implement and sustain PNDTD. In-depth semistructured interviews with six key informants selected through intentional sampling were conducted in August-December 2008. Interviewees were senior officers at the Ministry of Health who were directly involved in the decision to scale up the program. Results yielded four elements pivotal to the decisionmaking process: scientific evidence, teamwork and leadership, strategic alliances, and program institutionalization. Each element contributed to building consensus, securing funding, attracting resources, and gaining lasting support from policymakers. Additionally, a review of available documentation led the authors to consider sociopolitical context and use of the media to be important factors. While research evidence for the effectiveness of mental health services in the primary care setting continues to accumulate, low- and middle-income countries should get started on the lengthy process of scaling up by incorporating the elements that led to decisionmaking and implementation of the PNDTD in Chile. PMID:23183564

  6. FACTORES SOCIO-ESTRUCTURALES Y EL ESTIGMA HACIA EL VIH/SIDA: EXPERIENCIAS DE PUERTORRIQUEÑOS/AS CON VIH/SIDA AL ACCEDER SERVICIOS DE SALUD

    PubMed Central

    RIVERA-DIAZ, MARINILDA; VARAS-DIAZ, NELSON; REYES-ESTRADA, MARCOS; SURO, BEATRIZ; CORIANO, DORALIS

    2013-01-01

    RESUMEN El estigma relacionado al VIH/SIDA continúa afectando la prestación de servicios de salud y el bienestar físico y mental de las personas con VIH/SIDA (PVS). Recientemente la literatura científica ha señalado la importancia de comprender las manifestaciones de estigma más allá de las interacciones individuales. Por tal razón, investigaciones recientes en y fuera de Puerto Rico enfatizan la importancia de entender cómo factores socio-estructurales (FSE) influyen en los procesos de estigmatización social. Con el propósito de examinar los FSE que influyen en las manifestaciones de estigma relacionado al VIH/SIDA, realizamos y analizamos nueve grupos focales compuestos por hombres y mujeres en tratamiento para el VIH/SIDA que habían tenido experiencias estigmatizantes. Los participantes identificaron FSE relacionados a las manifestaciones de estigma, tales como el uso de viviendas especializadas, descentralización de los servicios de salud y el desarrollo de protocolos administrativos excluyentes en los servicios de salud. Los resultados demuestran la importancia de considerar los FSE en el desarrollo e implementación de intervenciones dirigidas a la población. PMID:24639599

  7. Sobre el estado evolutivo de ? Pictoris

    NASA Astrophysics Data System (ADS)

    Brunini, A.; Benvenuto, O. G.

    Desde el descubrimiento de fuertes excesos infrarrojos en ? Pictoris, esta estrella ha sido muy estudiada y es considerada candidata a poseer un sistema planetario propio. ? Pic está rodeada de un disco asimétrico de polvo que se observa de canto y que esta vacío a distancias <= 40 AU. Esto se considera una fuerte evidencia en favor de la presencia de (al menos) un planeta gigante. Recientemente se han observado líneas de material circunestelar que se han interpretado como consecuencia de la caída de objetos cometarios sobre esta estrella. Recientemente se ha utilizado la existencia del disco de polvo para atribuir una edad corta (pre - secuencia principal) a ?Pic. Sin embargo, la evaporación de estos cometas provee suficiente polvo como para explicar la presencia del disco observado sin necesidad de edades cortas. En este trabajo mostramos que la comparación entre la tasa de impactos cometarios estimada en el Sistema Solar para diferentes etapas de su evolución y los datos observados en ? Pic indica edades avanzadas para ? Pic. Esta estimación debe tomarse con cautela ya que depende de la estructura de los sistemas planetarios. Además mostramos que, desde el punto de vista de la evolución estelar y con las incertezas presentes en la luminosidad y la temperatura efectiva, existe un continuo de edades posible para ? Pic. Sin embargo, empleando los datos provenientes de los flujos cometarios encontramos que una edad prolongada es consistente con ambos tratamientos.

  8. Esquizofrenia y trastorno en el consumo de sustancias: prevalencia y characterísticas sociodemográficas en la población Latina

    PubMed Central

    Jiménez-Castro, Lorena; Raventós-Vorst, Henriette; Escamilla, Michael

    2012-01-01

    El interés por comprender la co-morbilidad de la esquizofrenia y el trastorno en el uso de sustancias, ha aumentado debido al incremento de este diagnóstico, a los efectos negativos observados en el sujeto y a los costos en los servicios de salud. Este trastorno dual puede tener efectos dramáticos en el curso clínico del trastorno psicótico tales como: mayores recaídas, re-hospitalizaciones, síntomas más severos, no adherencia al tratamiento antipsicótico, cambios marcados del humor, aumento en el grado de hostilidad e ideación suicida, así como alteraciones en otras áreas del funcionamiento incluyendo violencia, victimización, indigencia y problemas legales. La literatura proveniente en particular de Estados Unidos y Europa sugiere que el rango de prevalencia para este diagnóstico puede oscilar entre el 10% hasta el 70%. En este estudio, revisamos la prevalencia del diagnóstico dual de esquizofrenia y trastorno en el uso sustancias, así como sus características sociodemográficas, con base en la literatura disponible alrededor del mundo dando énfasis en la poblacion latina. A pesar de que este diagnóstico es ampliamente aceptado, se conoce poco sobre su prevalencia en la población latina, sobre los factores ambientales, demográficos, clínicos y otras características de estos individuos. Un mejor conocimiento sobre este diagnóstico permitiría mejorar los métodos para la detección y adecuada valoración del trastorno en el uso de sustancias en personas con trastornos metales severos como la esquizofrenia. PMID:21404151

  9. DISYUNTIVAS EN LAS CONCEPCIONES SOBRE AUTONOMÍA Y BENEFICENCIA QUE AFECTAN LA TERAPÉUTICA DEL INTENTO SUICIDA1

    PubMed Central

    Mondragón, Liliana; Monroy, Zuraya; Ito, Ma. Emily; Medina-Mora, Dra. Ma. Elena

    2010-01-01

    El objetivo del trabajo es conocer las disyuntivas entre los principios de beneficencia y autonomía, que se presentan en la relación médico-paciente, durante la terapéutica del intento de suicidio. La investigación se realizó en dos hospitales psiquiátricos de la Ciudad de México. La muestra incluyó a tres sujetos con intento de suicidio, mayores de 18 años, que eran atendidos en consulta externa a causa de una lesión autoinfligida en el último año, y a tres psiquiatras que trataban a estos pacientes. La información se obtuvo previo consentimiento informado en entrevistas individuales. Se llevó a cabo un análisis de discurso argumentado para encontrar los significados que los participantes otorgaron a los principios bioéticos y las posibles disyuntivas entre éstos. Las discordancias entre la beneficencia y la autonomía estuvieron relacionadas con el beneficio del tratamiento, el respeto por los valores y las creencias de los pacientes, entre otros. Este trabajo presenta consideraciones éticas relevantes en el escenario clínico, al ofrecer al psiquiatra un análisis bioético que le permita actuar de acuerdo con la beneficencia y respetando la autonomía del paciente frente a casos de intento de suicidio y, de esta forma procurar una mejor atención para ellos. PMID:20830214

  10. Life Course Experiences, Pain and Suffering: A Case Study of an Older Mexican American Woman with Mobility Impairment

    PubMed Central

    Walker, Janiece L.; Harrison, Tracie C.; Hendrickson, Sherry G.

    2012-01-01

    There is a dearth of literature examining how adversity shapes the experiences of pain and/or suffering in a middle aged Mexican American women. The purpose of this qualitative descriptive study was to understand pain and suffering from a life course perspective as described by a Mexican American woman aging with early onset mobility impairment. This Hispanic woman experienced episodes of abuse and rejection over the life course, which may have significantly influenced her pain and suffering experience in adulthood. This adds to the literature on how adversity influences later life pain experience and provides insight on why pharmacological treatment alone may not be as successful as a holistic intervention. Hay escasez de literatura que examine cómo la adversidad da forma a las experiencias de dolor y / o sufrimiento en mujeres mexicana-americana mayores de edad. El propósito de este estudio descriptivo cualitativo fue comprender el dolor y el sufrimiento desde una perspectiva de ciclo de vida como descrito por una mujer mexicana-americana envejeciendo con inicio temprano de deterioro de movilidad. Esta Latina experimentó episodios de maltrato y rechazo, que se percibió haber afectado su experiencia de dolor y sufrimiento luego como adulta. Este estudio aumenta la literatura sobre cómo la adversidad influya la experiencia de dolor más tarde en la vida, y nos permite comprender mejor como el tratamiento farmacológico por sí solo no es tan exitoso como pueda ser una intervención integral. PMID:24830728

  11. Hydrodynamic model of cells for designing systems of urban groundwater drainage

    NASA Astrophysics Data System (ADS)

    Zimmermann, Eric; Riccardi, Gerardo

    2000-08-01

    An improved mathematical hydrodynamic quasi-two-dimensional model of cells, CELSUB3, is presented for simulating drainage systems that consist of pumping well fields or subsurface drains. The CELSUB3 model is composed of an assemblage of algorithms that have been developed and tested previously and that simulate saturated flow in porous media, closed conduit flow, and flow through pumping stations. A new type of link between aquifer cells and drainage conduits is proposed. This link is verified in simple problems with well known analytical solutions. The correlation between results from analytical and mathematical solutions was considered satisfactory in all cases. To simulate more complex situations, the new proposed version, CELSUB3, was applied in a project designed to control the water-table level within a sewer system in Chañar Ladeado Town, Santa Fe Province, Argentina. Alternative drainage designs, which were evaluated under conditions of dynamic recharge caused by rainfall in a critical year (wettest year for the period of record) and a typical year, are briefly described. After analyzing ten alternative designs, the best technical-economic solution is a subsurface drainage system of closed conduits with pumping stations and evacuation channels. Résumé. Un modèle hydrodynamique perfectionné de cellules en quasi 2D, CELSUB3, est présenté dans le but de simuler des systèmes de drainage qui consistent en des champs de puits de pompage ou de drains souterrains. Le modèle CELSUB3 est composé d'un assemblage d'algorithmes développés et testés précédemment et qui simulent des écoulements en milieu poreux saturé, en conduites et dans des stations de pompage. Un nouveau type de lien entre des cellules d'aquifères et des drains est proposé. Ce lien est vérifié dans des problèmes simples dont les solutions analytiques sont bien connues. La corrélation entre les résultats des solutions analytiques et des solutions mathématiques a été considérée comme satisfaisante dans tous les cas. Afin de simuler des situations plus complexes, la nouvelle version proposée, CELSUB3, a été mise en œuvre dans un projet destiné à contrôler le niveau de la nappe à l'intérieur d'un système d'égouts, dans la ville de Chaar Ladeado (province de Santa Fe, Argentine). Différentes organisations du projet de drainage, qui ont été testées pour des conditions de recharge dynamique causées par la pluie au cours d'une année critique (la plus humide de la chronique disponible) et une année typique, sont brièvement décrites. Après analyse de dix organisations différentes, la meilleure solution technico-économique retenue est un système de drainage souterrain de conduites avec des stations de pompage et des canaux d'évacuation. Resumen. Se presenta un modelo matemático hidrodinámico cuasi-bidimensional de celdas, CELSUB3, apto para la simulación integral de sistemas de drenaje subterráneo basados en campos de bombeo o drenes subsuperficiales. El modelo de simulación presenta un ensamble de algoritmos, previamente desarrollados y testeados, que representan al escurrimiento a través del medio poroso saturado, escurrimiento en conducciones cerradas, estaciones de bombeo, etc. En la estructura del modelo se propone un nuevo tipo de vinculación entre celdas acuíferas y conductos de drenaje, la cual es verificada en problemas simples con solución analítica conocida arrojando, en todos los casos, resultados satisfactorios. Abordando situaciones más complejas, la nueva versión propuesta fue aplicada en un proyecto de control de niveles freáticos que acompaña un sistema de conductos cloacales, en la localidad de Chañar Ladeado, Santa Fe, Argentina. Se describen las alternativas de drenaje consideradas las cuales fueron evaluadas bajo recargas dinámicas provocadas por años críticamente lluviosos y en situaciones típicas. Los resultados derivados permitieron definir, tras analizar una decena de proyectos alternativos, la mejor solución técnico-económica consistente en un sistema de drenes subte

  12. Scheme for development of monitoring networks for springs in Bavaria, Germany

    NASA Astrophysics Data System (ADS)

    Bender, Steffen; Einsiedl, Florian; Wohnlich, Stefan

    2001-03-01

    The present groundwater monitoring network in Bavaria consists mostly of wells and only a small number of natural groundwater springs, all of which are analyzed for mainly the common physical and chemical constituents in groundwater. In order to develop a long-term groundwater management plan for all the groundwater resources of Bavaria, the Bavarian State Office for Water Management intends to establish a separate spring-monitoring network throughout the 11 groundwater provinces of the state. As a first step, significant physicochemical parameters that show considerable annual fluctuation (after monitoring 1-3 years) were determined at 21 springs or spring systems to create a basic data set to guide future monitoring. A selection procedure was developed around four parameters: (1) geological units, which includes the principal aquifers; (2) rate of spring discharge; (3) land utilization within a catchment; and (4) approximate size of the subterranean catchment. However, in the initial phase of the study, only the first three parameters were investigated. These parameters established a matrix for evaluating each groundwater region of Bavaria to aid in the selection of additional springs for the proposed monitoring network. Résumé. Le réseau actuel de surveillance des eaux souterraines en Bavière consiste surtout en des puits avec seulement un petit nombre de sources, tous analysés pour l'essentiel pour les composants courants physiques et chimiques des eaux souterraines. Afin de développer un plan de gestion à long terme des eaux souterraines de la Bavière, l'Office bavarois pour la gestion de l'eau cherche à mettre en place un réseau séparé de surveillance des sources dans les onze provinces hydrogéologiques du lander. Dans un premier temps, les paramètres physico-chimiques significatifs qui présentent des variations annuelles considérables, après 1 à 3 ans de surveillance, ont été déterminés à 21 sources ou groupes de sources pour constituer un jeu de données de base pour guider la future surveillance. Une procédure de sélection a été développée autour de quatre paramètres: (1) les unités géologiques, comprenant les principaux aquifères, (2) le débit des sources, (3) l'occupation du sol dans le bassin, et (4) la dimension approximative du bassin d'alimentation souterrain. Toutefois, dans la phase initiale de l'étude, seuls les trois premiers paramètres ont été étudiés. Ces paramètres constituent une matrice d'évaluation de chaque région hydrogéologique de Bavière pour aider à la sélection de sources supplémentaires destinées au réseau de surveillance proposé. Resumen. La red de muestreo actual de aguas subterráneas en Bavaria (Alemania) está formada sobre todo por pozos, mientras que apenas hay unos pocos manantiales naturales. Los análisis incluyen, principalmente, los parámetros físico-químicos habituales. Con el objeto de desarrollar un plan de gestión de las aguas subterráneas en Bavaria a largo plazo, el Consejo del Estado para la Gestión del Agua pretende establecer una red de muestreo de manantiales diferenciada en las once regiones en que se divide el estado desde el punto de vista de las aguas subterráneas. Como primer paso, se determinaron los parámetros físico-químicos significativos que mostraban una fluctuación anual considerable (tras un muestreo de 1 a 3 años), con la finalidad de crear una base de datos elemental que canalizara los muestreos futuros. Se desarrolló un procedimiento de selección con base en cuatro parámetros: (1) unidades geológicas y acuíferos principales; (2) caudal del manantial; (3) uso del suelo dentro de la cuenca; y (4) tamaño aproximado de la zona de captación subterránea. Sin embargo, sólo se investigaron los tres primeros parámetros durante la fase inicial del estudio. Con ellos, se estableció una matriz para evaluar cada zona acuífera dentro de Bavaria y ayudar en la inclusión de otros manantiales en la red de muestro propuesta.

  13. Distribution of stable isotopes in arid storms . II. A double-component model of kinematic wave flow and transport

    NASA Astrophysics Data System (ADS)

    Yakirevich, Alexander; Dody, Avraham; Adar, Eilon M.; Borisov, Viacheslav; Geyh, Mebus

    A new mathematical method based on a double-component model of kinematic wave flow and approach assesses the dynamic isotopic distribution in arid rain storms and runoff. This model describes the transport and ?18O evolution of rainfall to overland flow and runoff in an arid rocky watershed with uniformly distributed shallow depression storage. The problem was solved numerically. The model was calibrated using a set of temporal discharge and ?18O distribution data for rainfall and runoff collected on a small rocky watershed at the Sede Boker Experimental Site, Israel. Simulation of a reliable result with respect to observation was obtained after parameter adjustment by trial and error. Sensitivity analysis and model application were performed. The model is sensitive to changes in parameters characterizing the depression storage zones. The model reflects the effect of the isotopic memory in the water within the depression storage between sequential rain spells. The use of the double-component model of kinematic wave flow and transport provides an appropriate qualitative and quantitative fitting between computed and observed ?18O distribution in runoff. RésuméUne nouvelle méthode mathématique basée sur un modèle à double composante d'écoulement et de transport par une onde cinématique a été développée pour évaluer la distribution dynamique en isotopes dans les précipitations et dans l'écoulement en région aride. Ce modèle décrit le transport et les variations des ?18O de la pluie vers le ruissellement et l'écoulement de surface dans un bassin aride rocheux où le stockage se fait dans des dépressions peu profondes uniformément réparties. Le problème a été résolu numériquement. Le modèle a été calibré au moyen d'une chronique de débits et d'une distribution des ?18O dans la pluie et dans l'écoulement de surface sur un petit bassin versant rocheux du site expérimental de Sede Boker (Israël). La simulation d'un résultat crédible par rapport aux observations a été obtenu après un ajustement des paramètres par une méthode d'essais et d'erreurs. L'analyse de sensibilité et l'application du modèle ont ensuite été réalisés. Le modèle est plutôt sensible aux changements des paramètres caractérisant les zones de stockage dans les dépressions. Le modèle rend compte de l'effet de mémoire isotopique dans l'eau dans le stockage des dépressions entre les événements séquentiels de pluie. L'utilisation d'un modèle à double composante d'écoulement et de transport par onde cinématique permet un ajustement qualitatif et quantitatif adapté entre les distributions des ?18O calculées et observées dans l'écoulement de surface. Resumen Un nuevo método matemático basado en un modelo de doble componente de onda cinemática de flujo y transporte permite caracterizar la distribución isotópica dinámica de las tormentas en zonas áridas y la escorrentía. Este modelo describe el transporte y la evolución del ?18O en la lluvia, flujo superficial y escorrentía en una cuenca rocosa de clima árido con detención superficial distribuida uniformemente. El modelo se calibró numéricamente utilizando un conjunto de datos de descarga temporal y de distribución de ?18O para lluvia y escorrentía recogida en una pequeña cuenca rocosa en el Centro de Experimentación de Sede Boker, Israel. Se obtuvo un buen ajuste a los datos tras un ajuste de parámetros mediante prueba y error. Se realizó un análisis de sensibilidad que indicó que el modelo resulta ser bastante sensible a cambios en los parámetros que caracterizan las zonas de baja detención superficial. El modelo también refleja el efecto de la memoria isotópica en el agua de estas zonas de detención entre los distintos periodos de lluvias. El uso de un modelo de doble componente de onda cinemática de flujo y transporte proporciona un buen ajuste cualitativo y cuantitativo entre los datos medidos y calculados de ?18O en la escorrentía.

  14. Reacciones de intercambio de carga

    NASA Astrophysics Data System (ADS)

    Errea, L. F.

    Se discute la validez de diversas metodologías y su aplicación al estudio de procesos de intercambio de carga electrónico entre iones y blancos atómicos y moleculares. Para energías de impacto entre 0.05 y 5 eV / amu se emplea el método cuántico de la Coordenada de Reacción Común (CRC). A mayores energías, se utiliza el método semiclásico iconal con un desarrollo de la función de onda dinámica en estados moleculares adiabáticos, modificados con un factor de traslación común (FTC). Estos estados pueden obtenerse con cálculos ab initio o empleando potenciales modelo. Cuando la ionización compite con la transferencia de carga, la inclusión de pseudoestados en estos desarrollos permite calcular simultáneamente las secciones eficaces de ambos procesos. Otra técnica utilizada es el método estadístico CTMC. En el tratamiento de colisiones ión-molécula (diatómica) contrastamos la aplicabilidad de distintos métodos, desde la llamada aproximación Franck-Condon hasta un desarrollo en estados vibrónicos, pasando por la aproximación súbita vibro-rotacional, obteniéndose secciones eficaces de captura electrónica total y a estados individuales, así como secciones de excitación vibracional a estados ligados y del continuo (disociación). En todos los casos es necesario calcular superficies de energía y los correspondientes acoplamientos dinámicos entre los estados. La aplicación de estos métodos permite determinar el grado de contaminación de los haces por estados metaestables en un experimento dado, el cambio en los resultados con diferentes isótopos, la importancia de procesos de doble captura, seguida de explosión culombiana, todo ello con precisión comparable a la de medidas experimentales, para sistemas de interés en distintos tipos de plasmas.

  15. Regulando la Enfermedad a través de la Definición y la Restricción: Profesionales de la Salud Hablan sobre el VIH/SIDA1

    PubMed Central

    Rivera, Souhail Malavé; Díaz, Nelson Varas

    2009-01-01

    Resumen Las profesiones de la salud tienen un papel social dual. Por un lado, velan por el mantenimiento de la salud de la población protegiendo el bien común. Por el otro, dictaminan las formas saludables, y por lo tanto socialmente apropiadas, de ser, actuar y pensar. Este último papel, está más ligado al control social de la población que a una preocupación altruista hacia la misma. A través de esta supervisión y control, se construyen los sujetos a los cuales todos/as debemos aspirar a ser para gozar de aceptación social. Los/as profesionales de la salud han jugado un rol protagónico en dicho proceso, siendo los agentes que delimitan y definen lo que es enfermo vs. saludable, útil vs. inútil, apropiado vs. inapropiado. En el caso de la epidemia del VIH, este esfuerzo se ha hecho cada vez más vigente ya que estos/as profesionales juegan un papel importante en el tratamiento de las personas que viven con VIH/SIDA (PVVS). Sin embargo, su función está plasmada de definiciones que sirven para criminalizar a las PVVS. El objetivo de este estudio fue explorar la manera en que una muestra de profesionales de la salud en Puerto Rico construyen a las PVVS. Con este propósito, entrevistamos 80 profesionales de la salud y estudiantes de estas profesiones. Estas entrevistas fueron grabadas, transcritas y sometidas a un análisis de discurso. Los resultados reflejaron que según las personas participantes: 1) la PVVS no es una persona “normal” o funcional bajo los estándares sociales debido a que su salud no se los permite, 2) representa una carga para la sociedad incluyendo familiares, amigos/as, el mundo del trabajo, e incluso para el gobierno, 3) debe ser vigilada porque representa un riesgo para la persona seronegativa que es descrita como saludable y productiva, y 4) necesita que su salud y conducta sexual sean controladas por vía legal y/o por las personas que representan las instituciones sociales, como lo son los/as profesionales de la salud. En este artículo abordamos el potencial rol de la psicología para servir como vehículo de reconstrucción de dichas nociones, tomando en consideración su propio rol en la formación y mantenimiento de dicho sujeto socialmente deseable. PMID:22025907

  16. Progress in the prognosis of adult Hodgkin's lymphoma in the past 35 years through clinical trials in Argentina: a GATLA experience.

    PubMed

    Pavlovsky, Santiago; Lastiri, Francisco

    2004-09-01

    The purpose of this study was to evaluate the trends in complete remission (CR) rate, disease-free survival (DFS), and overall survival (OS) through 35 years of Grupo Argentino de Tratamiento de la Leucemia Aguda (GATLA) clinical trials. A total of 1,254 adult patients with Hodgkin's Lymphoma were evaluated according to seven consecutive protocols. This 35-year study was divided into three phases. The patients in the first phase (1968-1985) were treated with CVPP (cyclophosphamide/vinblastine/procarbazine/prednisone) plus involved-field radiotherapy (IFRT). In the CVPP regimen, cyclophosphamide and vinblastine were administered intravenously on day 1 and prednisone and procarbazine were administered orally on days 1-14 every 28 days. The second phase (1986-1996) used mainly reinforced CVPP with cyclophosphamide and vinblastine on days 1-8 plus IFRT. The third phase (1997-2003) used ABVD(doxorubicin/bleomycin/vinblastine/dacarbazine) plus IFRT. In clinical stage I/II, the CR rate was 86% in 252 patients treated in the first phase and DFS and OS were 57% and 78% at 5 years and 50% and 71% at 10 years. The second phase had 148 patients with clinical stage I/II disease, and the CR rate was 91%, 5-year DFS and OS were 78% and 90%, and 10-year DFS and OS were 70% and 83%. The third phase had 182 patients with clinical stage I/II disease, and the CR rate was 95%, 5-year DFS and OS were 87% and 96%, and 10-year DFS and OS were not reached. The statistical difference was P = 0.016 in terms of CR and P < 0.001 in terms of DFS and OS. In the first phase of 394 patients with clinical stage III/IV disease, the CR rate was 71%, DFS and OS at 5 years were 37% and 62%, and DFS and OS at 10 years were 32% and 53%. In the second phase of 164 patients with clinical stage III/IV disease, the CR rate was 84%, DFS and OS at 5 years were 66% and 80%, and DFS and OS at 10 years were 60% and 75%. In the third phase of 114 patients with clinical stage III/IV disease, the CR rate was 88% and DFS and OS at 5 years were 60% and 90%. The DFS and OS were not reached at 10 years. The differences among the 3 phases in CR, DFS and OS were highly significant (P < 0.001). PMID:15453925

  17. Capture-zone design in an aquifer influenced by cyclic fluctuations in hydraulic gradients

    NASA Astrophysics Data System (ADS)

    Zawadzki, Willy; Chorley, Don; Patrick, Guy

    2002-10-01

    Design of a groundwater pumping and treatment system for a wood-treatment facility adjacent to the tidally influenced Fraser River estuary required the development of methodologies to account for cyclic variations in hydraulic gradients. Design of such systems must consider the effects of these cyclic fluctuations on the capture of dissolved-phase contaminants. When the period of the cyclic fluctuation is much less than the travel time of the dissolved contaminant from the source to the discharge point, the hydraulic-gradient variations resulting from these cycles can be ignored. Capture zones are then designed based on the average hydraulic gradient determined using filter techniques on continuous groundwater-level measurements. When the period of cyclic fluctuation in hydraulic gradient is near to or greater than the contaminant travel time, the resulting hydraulic-gradient variations cannot be ignored. In these instances, procedures are developed to account for these fluctuations in the capture-zone design. These include proper characterization of the groundwater regime, assessment of the average travel time and period of the cyclic fluctuations, and numerical techniques which allow accounting for the cyclic fluctuations in the design of the capture zone. Résumé. L'étude d'un système de pompage et de traitement de l'eau souterraine d'une usine de traitement du bois proche de l'estuaire de la rivière Fraser, influencé par les marées, a nécessité la mise au point de méthodologies pour prendre en compte les variations cycliques de gradients hydrauliques. L'étude de tels systèmes doit considérer les effets de ces variations cycliques sur l'extraction des contaminants en phase dissoute. Lorsque la période des variations cycliques est très inférieure au temps de parcours du contaminant dissous entre la source et le point d'émergence, les variations du gradient hydraulique résultant de ces cycles peuvent être ignorées. Les zones d'extraction sont alors réalisées sur la base du gradient hydraulique moyen déterminé au moyen de techniques de filtrage sur des mesures continues de la piézométrie. Lorsque la période de la fluctuation cyclique dans le gradient hydraulique est proche de ou supérieure au temps de parcours du contaminant, les variations résultantes de gradient hydraulique ne peuvent plus être ignorées. Dans ces cas-là, des procédures ont été mises au point pour prendre en compte ces fluctuations dans la conception de la zone d'extraction. Celles-ci prennent en considération la caractérisation propre du régime de la nappe, l'évaluation du temps de parcours moyen et de la période des fluctuations cycliques, et des techniques numériques qui permettent de considérer les fluctuations cycliques dans la conception de la zone d'extraction. Resumen. El diseño de un sistema de bombeo y tratamiento de aguas subterráneas para una instalación de manufactura de madera que está próxima al estuario del río Fraser, sometido a la influencia de las mareas, ha requerido el desarrollo de metodologías para tener en cuenta las variaciones cíclicas de los gradientes hidráulicos. El diseño de tales sistemas debe considerar los efectos de las fluctuaciones cíclicas en la captura de contaminantes en fase disuelta. Cuando el período de la fluctuación cíclica es mucho menor que el tiempo de tránsito del contaminante disuelto entre el punto de entrada y el de descarga, se puede ignorar las variaciones del gradiente hidráulico provocadas por dichos ciclos. Las zonas de captura se diseñan entonces en función del gradiente hidráulico promedio, que se determina mediante técnicas de filtrado de medidas continuas del nivel piezométrico. Cuando el período de la fluctuación cíclica del gradiente hidráulico es comparable o mayor que el tiempo de tránsito del contaminante, no puede ignorarse las variaciones resultantes en el gradiente hidráulico. En ese caso, se tiene que desarrollar procedimientos para contar con las fluctuaciones en el diseño de las zonas de captura. Ello implica una ad

  18. Breakfast of champions or kiss of death? Survival and sexual performance of protein-fed, sterile Mediterranean fruit flies (Diptera: Tephritidae)

    SciTech Connect

    Yuval, B.; Maor, M.; Levy, K. [Dept. of Entomology, Hebrew University, PO 12, Rehovot, 76100 (Israel); Kaspi, R. [Dept. of Entomology, University of California, Davis CA 95616 (United States); Taylor, P. [Dept. of Psychology, Macquarie University, NSW 2109 (Australia); Shelly, T. [USDA-APHIS, 41-650 Ahiki Street, Waimanalo, HI 96795 (United States)

    2007-03-15

    The sterile insect technique (SIT) is increasingly being used around the world to control Ceratitis capitata (Wiedemann) (Diptera: Tephritidae), the Mediterranean fruit fly as part of an area-wide integrated approach. One option that may improve the effectiveness of the SIT, by increasing the sexual competitiveness of released sterile males, consists of feeding males protein during the post-teneral stage, a diet that increases sexual performance of wild males. We examine the effects of diet on the successive hurdles males must overcome in order to inseminate females, i.e., joining leks, copulating females, having their sperm stored and inhibition of female remating. In addition, we address the effects of diet on post-release foraging success, longevity, and the ability to withstand starvation. While protein feeding universally increases the sexual success of wild males, its effect on sterile males varies with strain, experimental settings, and environmental conditions. In some cases, treatments that resulted in the best sexual performance were significantly associated with increased vulnerability to starvation. However, no particular diet affected the ability of sterile males to find nutrients in the field when these where available. We suggest it may be better to release relatively short-lived flies that are highly competitive, rather than long-lived, sexually ineffective ones. (author) [Spanish] El uso de la tecnica de insecto esteril (TIE) esta aumentando alrededor del mundo para el control de Ceratitis capitata (Wiedemann) (Diptera: Tephritidae), la mosca mediterranea de la fruta como parte de un enfoque integrado por toda el area. Una opcion que puede mejorar la eficiencia de TIE, por medio del aumento de la capacidad de los machos esteriles liberados para competir, consiste en la alimentacion de los machos con proteina durante la etapa de pos-teneral, una dieta que aumenta el desempeno sexual de los machos naturales. Nosotros examinamos los efectos de la dieta sobre los obstaculos sucesivos que los machos tienen que superar para inseminar las hembras, i.e., unir con otros machos en areas para el apareamiento, copula de las hembras, almacenar esperma e inhibir el re-apareamiento de hembras. Ademas discutimos los efectos de la dieta sobre el exito de su actividad forrajera despues de ser liberados, la longevidad y la habilidad para aguantar la inanicion. Mientras que la alimentacion con proteina universalmente aumentan el exito sexual de los machos naturales, su efecto sobre los machos esteriles varia segun la raza, el lugar de los experimentos y las condiciones ambientales. En algunos casos, los tratamientos que resultaron con mejor desempeno sexual fueron asociados significativamente con el aumento de la vulnerabilidad a la inanicion. Sin embargo, ninguna dieta en particular afecto la habilidad de los machos esteriles para encontrar nutrientes en el campo cuando fueron disponibles. Nosotros sugerimos que puede ser mejor el liberar moscas que tienen una vida relativamente corta y que son mas competidoras, en vez de moscas que tienen una vida larga y sexualmente inefectiva. (author)

  19. Impact of Chloroquine on Viral Load in Breast Milk

    PubMed Central

    Semrau, Katherine; Kuhn, Louise; Kasonde, Prisca; Sinkala, Moses; Kankasa, Chipepo; Shutes, Erin; Vwalika, Cheswa; Ghosh, Mrinal; Aldrovandi, Grace; Thea, Donald M.

    2006-01-01

    Summary The anti-malarial agent chloroquine has activity against HIV. We compared the effect of chloroquine (n = 18) to an anti-malarial agent without known anti-HIV-activity, sulfadoxine-pyrimethamine (n = 12), on breast milk HIV RNA levels among HIV-infected breastfeeding women in Zambia. After adjusting for CD4 count and plasma viral load, chloroquine was associated with a trend towards lower levels of HIV RNA in breast milk compared with sulfadoxine-pyrimethamine (P 0.05). Higher breastmilk viral load was also observed among women receiving presumptive treatment = for symptomatic malaria compared with asymptomatic controls and among controls reporting fever in the prior week. Further research is needed to determine the potential role of chloroquine in prevention of HIV transmission through breastfeeding. Impacte de la chloroquine sur la charge virale dans le lait maternelle La chloroquine, agent antimalarique, a une activité contre le VIH. Nous avons comparé l’effet de la chloroquine à celui d’un autre agent antimalarique, la sulfadoxine-pyrimethamine, dont l’activité sur le VIH n’est pas connue, en mesurant les taux d’ARN de VIH dans le lait maternel de femmes allaitantes infectées par le VIH en Zambie. Après ajustement pour les taux de CD4 et la charge virale dans le plasma, la chloroquine comparée à la sulfadoxine pyrimethamine était associée à une tendance vers des teneurs plus bas en ARN de VIH dans le lait maternel (P = 0,05). Des charges virales plus élevées dans le lait maternel étaient aussi observées chez des femmes recevant un traitement présomptif pour des symptômes de malaria par rapport aux contrôles asymptomatiques et par rapport à des contrôles rapportant de la fièvre durant la première semaine. Des études supplémentaires sont nécessaires pour déterminer le rôle potentiel de la chloroquine dans la prévention de la transmission du VIH par l’allaitement maternel. mots clésVIH, malaria, allaitement maternel, chloroquine, sulfadoxine-pyrimethamine, charge virale du lait maternel, fièvre Impacto de la cloroquina en la carga viral de la leche materna El antimalárico cloroquina tiene actividad frente al VIH. Comparamos el efecto de la cloroquina (n = 18) frente a un antimalárico sin actividad anti-VIH conocida, la sulfadoxina-pirimetamina (n = 12), en los niveles de ARN en la leche materna de mujeres infectadas con VIH, en Zambia. Después de ajustar para recuento de CD4 y la carga viral en plasma, se asoció a la cloroquina con una tendencia hacia menores niveles de ARN del VIH en leche materna, comparado con la sulfadoxina pirimetamina (P = 0.05). También se observó una mayor carga viral en la leche materna de mujeres recibiendo tratamiento presuntivo para malaria sintomática, que en los controles asintomáticos y controles que habáan reportado fiebre la semana anterior. Es necesario realizar más estudios para determinar el papel potencial de la cloroquina en la prevención de la trasmisión de VIH a través de la lactancia materna. palabras claveVIH, malaria, lactancia materna, cloroquina, sulfadoxina pirimetamina, transmisión vertical, leche materna, carga viral, fiebre PMID:16772000