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Sample records for marco institucional venezolano

  1. 33 CFR 110.74 - Marco Island, Marco River, Fla.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Marco Island, Marco River, Fla. 110.74 Section 110.74 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.74 Marco Island, Marco River, Fla....

  2. History of San Marco

    NASA Technical Reports Server (NTRS)

    Caporale, A. J.

    1968-01-01

    A brief history is reported of the first San Marco project, a joint program of the United States and Italy. The Project was a three phase effort to investigate upper air density and associated ionosphere phenomena. The initial phase included the design and development of the spacecraft, the experiments, the launch complex, and a series of suborbital flights, from Wallops Island. The second phase, consisting of designing, fabricating, and testing a spacecraft for the first orbital mission, culminated in an orbital launch also from Wallops Island. The third phase consisted of further refining the experiments and spacecraft instrumentation and of establishing a full-bore scout complex in Kenya. The launch of San Marco B, in April 1967, from this complex into an equatorial orbit, concluded the initial San Marco effort.

  3. Marcos Moshinsky - teacher, colleague, scientist

    NASA Astrophysics Data System (ADS)

    Wolf, Kurt Bernardo

    2010-06-01

    It is said that a man lives every time his name is pronounced, when his ideas are discussed, and when the result of his actions continues to benefit the community. In this regard, Marcos Moshinsky will be in the midst of our generation of students and colleagues as we often refer to his careful instruction and generous collaboration. And beyond, his name will be remembered for as long as his seminal works on quantum and nuclear physics, group theoretical methods, and mathematics, remain in the foundations of the edifice of science.

  4. The Mark 15 Marco Library and Recent Updating of the Marco Code

    SciTech Connect

    Parks, P.B.

    2001-08-09

    This report discusses two tasks: (1) introduction of the Mark 15-MARCO library within the context of an overview of the methodology of MARCO and (2) assessment of the accuracy of MARCO calculations of the Mark 15 MOC at beginning of cycle.

  5. San Marcos Astronomical Project and Doctoral Prospectus

    NASA Astrophysics Data System (ADS)

    Aguilar, M. L.

    2009-05-01

    The Universidad Nacional Mayor de San Marcos, UNMSM, in Lima, Perú, is the only Peruvian institution working for the peruvian astronomical development as a career since 1970. We are conforming a network with international friend astronomers to invite them as Visiting Lectures to assure the academic level for the future doctoral studies in the UNMSM. The Chancellor of UNMSM has decided that the Astronomical Project is a UNMSM Project, to encourage and advance in this scientific and strategical area, to impulse the modernity of Peru, the major effort will be the building of the San Marcos Astronomical Observatory, with a telescope of 1 meter aperture.

  6. In memory of Marcos Vidal (1974-2016).

    PubMed

    Cagan, Ross; Gottlieb, Eyal

    2016-03-01

    With the untimely death of Marcos Vidal, we have lost a good friend and a creative, brilliant colleague who made important contributions to the field of cancer biology through fruit fly research. Marcos began his research into Drosophila at Ross Cagan's laboratory in 2003, first at Washington University in St Louis and later at Mount Sinai Hospital in New York. In 2009 Marcos was appointed as Research Group Leader at the Beatson Institute for Cancer Research in Glasgow. PMID:26758990

  7. Discovering Marco Polo: A Resource Guide for Teachers.

    ERIC Educational Resources Information Center

    Stanford Univ., CA. Stanford Program on International and Cross Cultural Education.

    This guide is designed for teachers who wish to teach about Marco Polo and his travels to China during the 13th century. The guide was originally developed for use with a television series about Marco Polo; it can successfully be used independent of the series, however. A prologue gives the reader a basic introduction to what is known of the life

  8. History of the Italian San Marco equatorial mobile range

    NASA Technical Reports Server (NTRS)

    Nesbitt, H. N.

    1971-01-01

    Events leading to the development of the San Marco Equatorial Range are presented. Included are background information leading to the cooperative space program between the United States and Italy, conceptual planning, training activities, equipment design and fabrication, and range utilization. The technical support provided the San Marco Program by Scout Project Office, and other NASA installations is described.

  9. 75 FR 22712 - Proposed Establishment of Class D Airspace; San Marcos, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-30

    ... Federal Aviation Administration 14 CFR Part 71 Proposed Establishment of Class D Airspace; San Marcos, TX...: This action proposes to establish Class D airspace at San Marcos, TX. Establishment of an air traffic... establishing Class D airspace at San Marcos Municipal Airport, San Marcos, TX. An air traffic control...

  10. Marco (Medical Record Communications) - System Concept, Design and Evaluation

    PubMed Central

    Moffatt, P. H.; Heisler, B. D.; Mela, W. D.; Alpert, J. J.; Goldstein, H.M.

    1978-01-01

    MARCO, an interfacility communication system, has been designed to promote safe relevant health care delivery to the inner city pediatric patient receiving care in a network consisting of Boston City Hospital and its affiliated Neighborhood Health Centers. This application of computer technology to communication of medical information compiled on an individual patient in multiple locations has implications for private group practice as well as other urban networks similar to our own. This paper provides the MARCO system concept, the system design and evaluation of its success after two years of operation.

  11. Reform in Spanish Education: The Institucion Libre de Ensenanza.

    ERIC Educational Resources Information Center

    Valis, Noel M.

    This document examines the development and influence of the Free Institute of Education (Institucion Libre de Ensenanza) and of its founder, Don Francisco Giner de los Rios, in late nineteenth century Spain. Founded in 1876 against a background of repression and reimposition of state-controlled education during the Bourbon Restoration the…

  12. The Philippine Press after Marcos: Restored Freedoms and New Problems.

    ERIC Educational Resources Information Center

    Guimary, Donald L.

    With the overthrow of Ferdinand Marcos from his 20-year rule of the Philippines, the news media regained its freedom and its voice, and now faces a new set of problems: low circulation, questionable ethical standards of reporters and their lack of experience, and ominous indications from the Corazon Aquino government that the administration might…

  13. 33 CFR 147.837 - Marco Polo Tension Leg Platform safety zone.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Marco Polo Tension Leg Platform... SECURITY (CONTINUED) OUTER CONTINENTAL SHELF ACTIVITIES SAFETY ZONES § 147.837 Marco Polo Tension Leg Platform safety zone. (a) Description. Marco Polo Tension Leg Platform, Green Canyon 608 (GC 608),...

  14. 33 CFR 147.837 - Marco Polo Tension Leg Platform safety zone.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Marco Polo Tension Leg Platform... SECURITY (CONTINUED) OUTER CONTINENTAL SHELF ACTIVITIES SAFETY ZONES § 147.837 Marco Polo Tension Leg Platform safety zone. (a) Description. Marco Polo Tension Leg Platform, Green Canyon 608 (GC 608),...

  15. 33 CFR 147.837 - Marco Polo Tension Leg Platform safety zone.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Marco Polo Tension Leg Platform... SECURITY (CONTINUED) OUTER CONTINENTAL SHELF ACTIVITIES SAFETY ZONES § 147.837 Marco Polo Tension Leg Platform safety zone. (a) Description. Marco Polo Tension Leg Platform, Green Canyon 608 (GC 608),...

  16. 33 CFR 147.837 - Marco Polo Tension Leg Platform safety zone.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Marco Polo Tension Leg Platform... SECURITY (CONTINUED) OUTER CONTINENTAL SHELF ACTIVITIES SAFETY ZONES § 147.837 Marco Polo Tension Leg Platform safety zone. (a) Description. Marco Polo Tension Leg Platform, Green Canyon 608 (GC 608),...

  17. 33 CFR 147.837 - Marco Polo Tension Leg Platform safety zone.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Marco Polo Tension Leg Platform... SECURITY (CONTINUED) OUTER CONTINENTAL SHELF ACTIVITIES SAFETY ZONES § 147.837 Marco Polo Tension Leg Platform safety zone. (a) Description. Marco Polo Tension Leg Platform, Green Canyon 608 (GC 608),...

  18. MarcoPolo-R near earth asteroid sample return mission

    NASA Astrophysics Data System (ADS)

    Barucci, Maria Antonietta; Cheng, A. F.; Michel, P.; Benner, L. A. M.; Binzel, R. P.; Bland, P. A.; Bhnhardt, H.; Brucato, J. R.; Campo Bagatin, A.; Cerroni, P.; Dotto, E.; Fitzsimmons, A.; Franchi, I. A.; Green, S. F.; Lara, L.-M.; Licandro, J.; Marty, B.; Muinonen, K.; Nathues, A.; Oberst, J.; Rivkin, A. S.; Robert, F.; Saladino, R.; Trigo-Rodriguez, J. M.; Ulamec, S.; Zolensky, M.

    2012-04-01

    MarcoPolo-R is a sample return mission to a primitive Near-Earth Asteroid (NEA) proposed in collaboration with NASA. It will rendezvous with a primitive NEA, scientifically characterize it at multiple scales, and return a unique sample to Earth unaltered by the atmospheric entry process or terrestrial weathering. MarcoPolo-R will return bulk samples (up to 2 kg) from an organic-rich binary asteroid to Earth for laboratory analyses, allowing us to: explore the origin of planetary materials and initial stages of habitable planet formation; identify and characterize the organics and volatiles in a primitive asteroid; understand the unique geomorphology, dynamics and evolution of a binary NEA. This project is based on the previous Marco Polo mission study, which was selected for the Assessment Phase of the first round of Cosmic Vision. Its scientific rationale was highly ranked by ESA committees and it was not selected only because the estimated cost was higher than the allotted amount for an M class mission. The cost of MarcoPolo-R will be reduced to within the ESA medium mission budget by collaboration with APL (John Hopkins University) and JPL in the NASA program for coordination with ESA's Cosmic Vision Call. The baseline target is a binary asteroid (175706) 1996 FG3, which offers a very efficient operational and technical mission profile. A binary target also provides enhanced science return. The choice of this target will allow new investigations to be performed more easily than at a single object, and also enables investigations of the fascinating geology and geophysics of asteroids that are impossible at a single object. Several launch windows have been identified in the time-span 2020-2024. A number of other possible primitive single targets of high scientific interest have been identified covering a wide range of possible launch dates. The baseline mission scenario of MarcoPolo-R to 1996 FG3 is as follows: a single primary spacecraft provided by ESA, carrying the Earth Re-entry Capsule, sample acquisition and transfer system provided by NASA, will be launched by a Soyuz-Fregat rocket from Kourou into GTO and using two space segment stages. Two similar missions with two launch windows, in 2021 and 2022 and for both sample return in 2029 (with mission duration of 7 and 8 years), have been defined. Earlier or later launches, in 2020 or 2024, also offer good opportunities. All manoeuvres are carried out by a chemical propulsion system. MarcoPolo-R takes advantage of three industrial studies completed as part of the previous Marco Polo mission (see ESA/SRE (2009)3, Marco Polo Yellow Book) and of the expertise of the consortium led by Dr. A.F. Cheng (PI of the NASA NEAR Shoemaker mission) of the JHU-APL, including JPL, NASA ARC, NASA LaRC, and MIT.

  19. MarcoPolo-R: Asteroid Sample Return Mission

    NASA Astrophysics Data System (ADS)

    Brucato, John Robert

    2012-07-01

    MarcoPolo-R is a sample return mission to a primitive Near-Earth Asteroid (NEA) selected for the assessment study in the framework of ESA Cosmic Vision 2015-25 program. MarcoPolo-R is an European-led mission with a proposed NASA contribution. MarcoPolo-R will rendezvous with a primitive carbon-rich NEA, scientifically characterize it at multiple scales, and return a unique sample to Earth unaltered by the atmospheric entry process or terrestrial weathering. The baseline target is a binary asteroid (175706) 1996 FG3, which offers a very efficient operational and technical mission profile. A binary target also provides enhanced science return. The choice of this target will allow new investigations to be performed more easily than at a single object, and also enables investigations of the fascinating geology and geophysics of asteroids that are impossible at a single object. Several launch windows have been identified in the time-span 2020-2024. The baseline mission scenario of MarcoPolo-R to 1996 FG3 foresees a single primary spacecraft, carrying the Earth re-entry capsule and sample acquisition and transfer system, launched by a Soyuz-Fregat rocket from Kourou. The scientific payload includes state-of-the-art instruments, e.g. a camera system for high resolution imaging from orbit and on the surface, spectrometers covering visible, near-infrared and mid-infrared wavelengths, a neutral-particle analyser, a radio science experiment and optional laser altimeter. If resources are available, an optional Lander will be added to perform in-situ characterization close to the sampling site, and internal structure investigations. MarcoPolo-R will allow us to study the most primitive materials available to investigate early solar system formation processes. The main goal of the MarcoPolo-R mission is to return unaltered NEA material for detailed analysis in ground-based laboratories. Only in the laboratory can instruments with the necessary precision and sensitivity be applied to individual components of the complex mixture of materials that forms an asteroid regolith, in orer to determine their precise chemical, mineralogical and isotopic composition. Such measurements are vital for revealing the evidence of stellar, interstellar medium, pre-solar nebula and parent body processes that are retained in primitive asteroidal material. In addition to addressing the exciting science goals, the MarcoPolo-R mission also involves technologies for which technical development programmes are well under way. It is the ideal platform to (i) demonstrate innovative capabilities such as: accurate planetary navigation and landing, sample return operational chain; (ii) prepare the next generation of curation facilities for extra-terrestrial sample storage and analysis; (iii) develop high speed re-entry capsule; (iv) pave the way as a pathfinder mission for future sample returns from bodies with high surface gravity.

  20. A geophysical study of the S. Marcos Quarteira fault, Portugal

    NASA Astrophysics Data System (ADS)

    Carvalho, J.; Torres, L.; Rocha, R.; Dias, R.; Mendes-Victor, L.

    2006-10-01

    The Algarve province is located in the southern part of Portugal, a few hundred kilometres North of the crossing E-W Eurasia-Africa plate boundary. It is characterized by moderate seismicity, with some important historical and instrumental earthquakes causing loss of lives and important material damages. It has therefore been the target of several seismic risk assessment projects financed by the Portuguese government and the European community. The CAPSA is one of these projects, in which extensive geological and geophysical studies were carried out. This paper discusses the application of the seismic reflection method as part of the project to confirm a fault location and to determine if it is (or not) an active fault. Seismic reflection profiles were collected to study and confirm the location of the S. Marcos-Quarteira fault in the Quarteira area. This is a regional fault that affects Paleozoic and Mesozoic rocks. A fault is observed in an outcrop near the Boliqueime village, located a few kilometres away from the study area and affects the Pleistocene cover sediments. The aim of this work was to verify if this active fault and the suspected location of the S. Marcos-Quarteira fault in Tertiary and Quaternary terrains was the same structure. Refraction interpretation of the reflection data and vertical electrical soundings were also used to complement the information. An important deformation was found in several seismic profiles that also affects Quaternary formations, in accordance with the observed seismicity. The probable location of the S. Marcos-Quarteira fault in the Quarteira area was confirmed, as well as its Quaternary activity, confirming an increased seismic risk scenario envisioned for the Algarve region of Portugal.

  1. Análisis del futuro marco de referencia internacional

    NASA Astrophysics Data System (ADS)

    Cionco, G. R.; Arias, E. F.

    La técnica de interferometría de muy larga línea de base (VLBI) se aplica hoy a la astrometría para el cálculo de posiciones precisas de radiofuentes extragalácticas. Por tratarse de objetos lejanos, sus movimientos propios aparentes pueden considerarse nulos; esta propiedad hace que los catálogos de radiofuentes extragalácticas VLBI constituyan la mejor materialización de un sistema de referencia celeste inercial definido cinemáticamente. La Unión Astronómica Internacional (IAU) recomendó la adopción de un nuevo sistema de referencia celeste internacional materializado por las coordenadas ecuatoriales de objetos extragalácticos observados con le técnica VLBI. Para superar la precisión astrométrica actual es necesaria una mejora en la modelización de aquellos fenómenos que pueden introducir desviaciones sistemáticas en el marco de referencia celeste. El objetivo de este trabajo es poner de manifiesto las sistematicidades presentes en los distintos marcos de referencia elaborados con el próposito de materializar el nuevo sistema de referencia celeste de la IAU. Para la comparación de los distintos marcos de referencia se propone un modelo de tres rotaciones diferenciales más un término lineal que procura absorber los efectos sistemáticos presentes en las coordenadas. Se analiza igualmente la estabilidad de la solución cuando se utilizan distintos conjuntos de objetos de definición.

  2. The San Marco 3 neutral atmosphere composition experiment

    NASA Technical Reports Server (NTRS)

    Pelz, D. T.; Newton, G. P.; Kasprzak, W. T.; Clem, T. D.

    1973-01-01

    The experimental instrumentation of the San Marco 3 satellite is described along with the calibration and operation. The instrumentation for the following experiments was included: an air density experiment for measuring the instantaneous drag force, and thus the neutral particle total mass density; a neutral atmosphere composition experiment for measuring the densities of helium, atomic and molecular oxygen, molecular nitrogen and argon; and a neutral atmosphere temperature experiment to determine the gas kinetic temperature by measuring molecular nitrogen density variations in an orificed spherical chamber as a function of angle of attack.

  3. Marco Todeschini - Space Dynamics and Psycho-Biophysics

    NASA Astrophysics Data System (ADS)

    Teodorani, M.

    2006-03-01

    This book is dedicated to the theoretical and experimental research carried out in the 20-th century, by Italian engineer and technical physicist Marco Todeschini. It describes the subjects of "space dynamics" and "psycho-biophysics" - two related physical sciences - whose foundations lay in the existence of the ether and of the vortexes that all bodies with mass produce in it. An entirely new cosmology is derived in which all the bodies in the universe - elementary particles, astronomical bodies, and the human being - are strictly related together.

  4. Vaccinia virus binds to the scavenger receptor MARCO on the surface of keratinocytes.

    PubMed

    MacLeod, Daniel T; Nakatsuji, Teruaki; Wang, Zhenping; di Nardo, Anna; Gallo, Richard L

    2015-01-01

    Patients with altered skin immunity, such as individuals with atopic dermatitis (AD), can have a life-threatening disruption of the epidermis known as eczema vaccinatum after vaccinia virus (VV) infection of the skin. Here, we sought to better understand the mechanism(s) by which VV associates with keratinocytes. The class A scavenger receptor known as MARCO (macrophage receptor with collagenous structure) is expressed on human and mouse keratinocytes and found to be abundantly expressed in the skin of patients with AD. VV bound directly to MARCO, and overexpression of MARCO increased susceptibility to VV infection. Furthermore, ligands with affinity for MARCO, or excess soluble MARCO, competitively inhibited VV infection. These findings indicate that MARCO promotes VV infection and highlights potential new therapeutic strategies for prevention of VV infection in the skin. PMID:25089661

  5. 75 FR 41983 - Establishment of Class D Airspace; San Marcos, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-20

    ... Federal Aviation Administration 14 CFR Part 71 Establishment of Class D Airspace; San Marcos, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action establishes Class D... Federal Register a notice of proposed rulemaking to establish Class D airspace for San Marcos...

  6. Role of Lysosomes in Silica-Induced Inflammasome Activation and Inflammation in Absence of MARCO

    PubMed Central

    Biswas, Rupa; Hamilton, Raymond F.

    2014-01-01

    MARCO is the predominant scavenger receptor for recognition and binding of silica particles by alveolar macrophages (AM). Previously, it was shown that mice null for MARCO have a greater inflammatory response to silica, but the mechanism was not described. The aim of this study was to determine the relationship between MARCO and NLRP3 inflammasome activity. Silica increased NLRP3 inflammasome activation and release of the proinflammatory cytokine, IL-1?, to a greater extent in MARCO?/? AM compared to wild type (WT) AM. Furthermore, in MARCO?/? AM there was greater cathepsin B release from phagolysosomes, Caspase-1 activation, and acid sphingomyelinase activity compared to WT AM, supporting the critical role played by lysosomal membrane permeabilization (LMP) in triggering silica-induced inflammation. The difference in sensitivity to LMP appears to be in cholesterol recycling since increasing cholesterol in AM by treatment with U18666A decreased silica-induced NLRP3 inflammasome activation, and cells lacking MARCO were less able to sequester cholesterol following silica treatment. Taken together, these results demonstrate that MARCO contributes to normal cholesterol uptake in macrophages; therefore, in the absence of MARCO, macrophages are more susceptible to a greater inflammatory response by particulates known to cause NLRP3 inflammasome activation and the effect is due to increased LMP. PMID:25054161

  7. Geochemical and hydrologic data for San Marcos Springs recharge characterization near San Marcos, Texas, November 2008--December 2010

    USGS Publications Warehouse

    Crow, Cassi L.

    2012-01-01

    During 2008–10, the U.S. Geological Survey, in cooperation with the San Antonio Water System, collected geochemical and hydrologic data in Bexar, Comal, and Hays Counties, Texas, to define and characterize the sources of recharge to San Marcos Springs. Precipitation samples were collected for stable isotope analysis at 1 site and water-quality samples were collected at 7 springs, 21 wells, and 9 stream sites in the study area between November 2008 and December 2010. Continuous water-quality monitors were installed in three springs, two wells, and at one stream site. Three continuous stream-gaging stations were installed to measure gage height and a stagedischarge rating was developed at two of the three sites. Depth to water below land surface was continuously measured in two wells.

  8. MarcoPolo-R: Mission and Spacecraft Design

    NASA Astrophysics Data System (ADS)

    Peacocke, L.; Kemble, S.; Chapuy, M.; Scheer, H.

    2013-09-01

    The MarcoPolo-R mission is a candidate for the European Space Agency's medium-class Cosmic Vision programme, with the aim to obtain a 100 g sample of asteroid surface material and return it safely to the Earth. Astrium is one of two industrial contractors currently studying the mission to Phase A level, and the team has been working on the mission and spacecraft design since January 2012. Asteroids are some of the most primitive bodies in our solar system and are key to understanding the formation of the Earth, Sun and other planetary bodies. A returned sample would allow extensive analyses in the large laboratory-sized instruments here on Earth that are not possible with in-situ instruments. This analysis would also increase our understanding of the composition and structure of asteroids, and aid in plans for asteroid deflection techniques. In addition, the mission would be a valuable precursor for missions such as Mars Sample Return, demonstrating a high speed Earth re-entry and hard landing of an entry capsule. Following extensive mission analysis of both the baseline asteroid target 1996 FG3 and alternatives, a particularly favourable trajectory was found to the asteroid 2008 EV5 resulting in a mission duration of 4.5 to 6 years. In October 2012, the MarcoPolo-R baseline target was changed to 2008 EV5 due to its extremely primitive nature, which may pre-date the Sun. This change has a number of advantages: reduced DeltaV requirements, an orbit with a more benign thermal environment, reduced communications distances, and a reduced complexity propulsion system - all of which simplify the spacecraft design significantly. The single spacecraft would launch between 2022 and 2024 on a Soyuz-Fregat launch vehicle from Kourou. Solar electric propulsion is necessary for the outward and return transfers due to the DeltaV requirements, to minimise propellant mass. Once rendezvous with the asteroid is achieved, an observation campaign will begin to characterise the asteroid properties and map the surface in detail. Five potential sampling sites will be selected and closely observed in a local characterisation phase, leading to a single preferred sampling site being identified. The baseline instruments are a Narrow Angle Camera, a Mid-Infrared Spectrometer, a Visible Near-Infrared Spectrometer, a Radio Science Experiment, and a Close-up Camera. For the sampling phase, the spacecraft will perform a touch-and-go manoeuvre. A boom with a sampling mechanism at the end will be deployed, and the spacecraft will descend using visual navigation to touch the asteroid for some seconds. The rotary brush sampling mechanism will be activated on touchdown to obtain a good quality sample comprising regolith dust and pebbles. Low touchdown velocities and collision avoidance are critical at this point to prevent damage to the spacecraft and solar arrays. The spacecraft will then move away, returning to a safe orbit, and the sample will be transferred to an Earth Re-entry Capsule. After a final post-sampling characterisation campaign, the spacecraft will perform the return transfer to Earth. The Earth Re-entry Capsule will be released to directly enter the Earth's atmosphere, and is designed to survive a hard landing with no parachute deceleration. Once recovered, the asteroid sample would be extracted in a sample curation facility in preparation for the full analysis campaign. This presentation will describe Astrium's MarcoPolo-R mission and spacecraft design, with a focus on the innovative aspects of the design.

  9. Marco Polo : an Italian Mission Scoring a lot of Records

    NASA Astrophysics Data System (ADS)

    di Pippo, Simonetta; Bracciaferri, Fabio M.

    2002-01-01

    The first astronaut of the European Astronaut Corps of Italian nationality, Roberto Vittori, will fly on a Soyuz capsule at the end of April 2002, opening a new era of space flight. The mission, sponsored by the Italian Space Agency, has been developed in the framework of an ESA- ROSAVIAKOSMOS agreement, reached in order to give European astronauts additional possibilities to fly. It's the first mission of this kind. In addition to that, this is the real first time in which a Soyuz mission is in the hands of two cosmonauts, and one of them is non Russian. On the same flight, in fact, Mark Shuttleworth, the second tourist in the history of space activities, is going to fly, performing also a set of scientific experiments. Marco Polo is also the first mission in which the two Agencies, ASI and ESA, are developing a joint commercialisation program, devoted to attire sponsors for improving research and development activities in the Human Spaceflight area. This will allow the two agencies to improve also the quality of life on Earth. A comprehensive scientific program is also foreseen accompanying Vittori on board, mainly in the field of life science. Experiments devoted to neurophysiology, arms rehabilitation, test of new materials for dressing in space, evaluation of the behaviour of the Nobel Prize Montalcini discovery named NGF (Nerve Growth Factor) will be performed on board. A R&D payload for Blood Pressure Measurements could have in the future commercial spin-off. In addition, a possible institutional sponsorship of the World Health Organization is under discussion. It will be the real first time in which a space mission gets this kind of sponsorship, and this strictly related to the World Health Day this year, devoted in promoting health throughout movement, i.e. "Move for Health". The Italian Space Agency proposed a joint combination of the two slogans, coupling the "Move for Health" message with the Italian "Space for Health" one. This is because of the Marco Polo scientific program, and because of an advanced training and rehabilitation protocol we have studied, to be applied to old population in order to improve their quality of life, through the parallelism between astronauts (in microgravity conditions) and aging population. The mission, at the time of the World Space Congress, will be already performed and the results can be presented.

  10. Near-Earth Object Exploration and Marco Polo-R

    NASA Technical Reports Server (NTRS)

    Abell, Paul

    2013-01-01

    A major goal for NASA's human spaceflight program is to send astronauts to near-Earth asteroids (NEAs) in the coming decades. Missions to NEAs would undoubtedly provide a great deal of technical and engineering data on spacecraft operations for future human space exploration while conducting in-depth scientific examinations of these primitive objects. However, prior to sending human explorers to NEAs, robotic investigations of these bodies would be required in order to maximize operational efficiency and reduce mission risk. These precursor missions to NEAs would fill crucial strategic knowledge gaps concerning their physical characteristics that are relevant for human exploration of these relatively unknown destinations. Therefore robotic investigations of NEAs, such as ESA's Marco Polo-R sample return mission to 2008 EV5, would allow NASA and its international partners to gain critical operational experience in performing complex tasks (e.g., close proximity operations, surface sample collection, etc.) under microgravity conditions at or near the surface of a potential human destination. This would provide an important synergy between the worldwide Science and Exploration communities, which will be crucial for development of future international deep space exploration architectures and has potential benefits for future exploration of other destinations beyond low-Earth orbit.

  11. Radar Tomography of Asteroids ASSERT / Marco Polo-R

    NASA Astrophysics Data System (ADS)

    Herique, A.; Zine, S.; Barucci, A.; Biele, J.; Ho, T.; Kofman, W. W.; Krause, C.; Michel, P.; Plettemeier, D.; Prado, J.; Souyris, J.; Ulamec, S.; Assert Team

    2011-12-01

    The internal structure of NEAs remains largely unknown. It is a key point for the understanding of asteroid accretion and dynamical evolution. From a science point of view, the internal structure is also a key point for the understanding of asteroid accretion and dynamical evolution. For risk management and mitigation, it is required to characterize whether a small asteroid will survive the transit through the atmosphere and also to define a deflection policy. There are some indirect evidences that a rubble pile structure is really common at least for objects larger than a few hundreds of meters in diameter. But a more precise characterisation of the internal structure is required, such as the size and the structure of the main blobs and their distribution within the NEAs main body as well as a statistical characterisation of the surface regolith in term of density and size distribution. Radar tomography is the only way to image the internal structure from decimetric to global scale in order to better understand the nature of the primary object and its posterior alterations. It is also a way to estimate the ratio between micro- and macro-porosity. Bistatic radar tomography is an original technique, developed with the CONSERT Experiment (Rosetta / ESA) to image ant characterize the internal structures of 67P/Churyumov-Gerasimeko with a signal transmitted from the Orbiter to the Lander. By regards to a more classical monostatic radar like Marsis (MarsExpress/ESA), this bistatic configuration requires limited resources (mass, power and dataflow) and increases the capacity of deep sounding. So ASSERT (ASteroid Sounding Experiment by Radiowave Transmission) is proposed to instrument a MASCOT-type lander e.g. as payload of the ESA Marco Polo R mission (ESA). The first addressed question is a rubble pile or a monolithic body: For a rubble pile, the tomography will allow to estimate the size distribution of the boulders by direct imaging or statistical analysis of the scattered signal. The estimation of the mean permittivity of the blobs is a way to estimate the macro- versus micro-porosity. Its spatial variations highlight the heterogeneity of the parent bodies and segregation mechanism during reaccretion. - And for a monolithic object, we can expect only micro-porosity. Then images of the body interior and spatial distributions of the permittivity give the heterogeneity. In a further analysis, the characterization of the heterogeneity by statistical or imagery approach is a key point to understand asteroid accretion and evolution: - is this body accreted or re-accreted from the same material or not, from similar parent bodies or not? - is there some evidence of collisional metamorphism with change in the porosity and or mineralogy? - is there some evidence of metamorphism per hydration? This advanced interpretation will be based on the sample return analysis and constitutes a complete recontextualization of the analyzed samples at the global body scale

  12. Gravity Investigations with the MarcoPolo-R Radio Science Experiment RSE

    NASA Astrophysics Data System (ADS)

    Andert, T. P.; Pätzold, M.; Bellerose, J.; Barriot, J. P.; Oberst, J.; Hahn, M.; Tellmann, S.; Remus, S.; Förstner, R.; Häusler, B.

    2013-09-01

    The ESA sample return mission MarcoPolo-R is one of the current candidate M3 missions. It will rendezvous with a primitive Near Earth Asteroid (NEA), scientifically characterize it at multiple scales, and return a unique sample to Earth [3] The determination of the global physical properties of the mission target, the Near Earth Asteroid 2008 EV5, is among others one science objective of the MarcoPolo-R mission. In this context one key parameter is the gravity field, especially GM (gravitational constant times the mass) and the low order gravity coefficients C20 and C22 of the asteroid.

  13. Protection against inhaled oxidants through scavenging of oxidized lipids by macrophage receptors MARCO and SR-AI/II.

    PubMed

    Dahl, Morten; Bauer, Alison K; Arredouani, Mohamed; Soininen, Raija; Tryggvason, Karl; Kleeberger, Steven R; Kobzik, Lester

    2007-03-01

    Alveolar macrophages (AMs) express the class A scavenger receptors (SRAs) macrophage receptor with collagenous structure (MARCO) and scavenger receptor AI/II (SRA-I/II), which recognize oxidized lipids and provide innate defense against inhaled pathogens and particles. Increased MARCO expression in lungs of ozone-resistant mice suggested an additional role protecting against inhaled oxidants. After ozone exposure, MARCO-/- mice showed greater lung injury than did MARCO+/+ mice. Ozone is known to generate oxidized, proinflammatory lipids in lung lining fluid, such as 5beta,6beta-epoxycholesterol (beta-epoxide) and 1-palmitoyl-2-(9'-oxo-nonanoyl)-glycerophosphocholine (PON-GPC). Intratracheal instillation of either lipid caused substantial neutrophil influx in MARCO-/- mice, but had no effect in MARCO+/+ mice. Normal AMs showed greater uptake in vitro of beta-epoxide compared with MARCO-/- AMs, consistent with SRA function in binding oxidized lipids. SR-AI/II-/- mice showed similar enhanced acute lung inflammation after beta-epoxide or another inhaled oxidant (aerosolized leachate of residual oil fly ash). In contrast, subacute ozone exposure did not enhance inflammation in SR-AI/II-/- versus SR-AI/II+/+ mice, reflecting increased AM expression of MARCO. These data identify what we believe to be a novel function for AM SRAs in decreasing pulmonary inflammation after oxidant inhalation by scavenging proinflammatory oxidized lipids from lung lining fluids. PMID:17332894

  14. Monitoring and Assessment of Regional Air Quality in China Using Space Observations (MarcoPolo)

    NASA Astrophysics Data System (ADS)

    van der A, Ronald; Ding, Jieying; Mijling, Bas; Bai, Jianhui

    2014-11-01

    In this paper we will present the FP7-project ’MarcoPolo’. The main objective of Marco Polo is to improve air quality monitoring, modelling and forecasting over China using satellite data. Within the preceeding DRAGON project AMFIC it was concluded that modelling of air quality are hampered by the rapidly changing emission data due to economic growth in China. In addition, air quality policies could not directly be related to changes in emissions. Therefore, within the MarcoPolo project, the focus will be placed on emission estimates from space and the refinement of these emission estimates by spatial downscaling and by source sector apportionment. A wide range of satellite data will be used from various satellite instruments to derive emission estimates for NOx, SO2, PM and biogenic sources. By combining these emission data with known information from the ground, a new emission database for MarcoPolo will be constructed. The improved emission inventory will be input to the regional and local air quality models.

  15. Final Educational Accomplishment Audit of the San Marcos Independent School District's Bilingual Education Program.

    ERIC Educational Resources Information Center

    Prochnow, Harold G.

    The final audit report (1972)73) on the Bilingual Education Program of the San Marcos Independent School District critiques the quality of the project and the audit. The 5 sections of the audit are: (1) introductory and general comments on the quality of the project evaluation and the comparative findings of the project evaluation and the audit;…

  16. Macrophage Receptor with Collagenous Structure (MARCO) Is Processed by either Macropinocytosis or Endocytosis-Autophagy Pathway

    PubMed Central

    Hirano, Seishiro; Kanno, Sanae

    2015-01-01

    The Macrophage Receptor with COllagenous structure (MARCO) protein is a plasma membrane receptor for un-opsonized or environmental particles on phagocytic cells. Here, we show that MARCO was internalized either by ruffling of plasma membrane followed by macropinocytosis or by endocytosis followed by fusion with autophagosome in CHO-K1 cells stably transfected with GFP-MARCO. The macropinocytic process generated large vesicles when the plasma membrane subsided. The endocytosis/autophagosome (amphisome) generated small fluorescent puncta which were visible in the presence of glutamine, chloroquine, bafilomycin, ammonia, and other amines. The small puncta, but not the large vesicles, co-localized with LC3B and lysosomes. The LC3-II/LC3-I ratio increased in the presence of glutamine, ammonia, and chloroquine in various cells. The small puncta trafficked between the peri-nuclear region and the distal ends of cells back and forth at rates of up to 2–3 μm/sec; tubulin, but not actin, regulated the trafficking of the small puncta. Besides phagocytosis MARCO, an adhesive plasma membrane receptor, may play a role in incorporation of various extracellular materials into the cell via both macropinocytic and endocytic pathways. PMID:26545255

  17. Evaluation Report of the San Marcos Independent School District's Bilingual Education Program.

    ERIC Educational Resources Information Center

    Harrison, Helene W.

    The San Marcos Independent School District's Bilingual Education Program for 1972-73 was evaluated in this report. The program consisted of 684 students in grades K-5 in 4 elementary schools. The majority of these students were Mexican American with only 18% monolingual English speakers. The program's objectives were, first, to provide bilingual…

  18. The San Marcos River Habitat Conservation Plan: Using HCP's as a Tool for Ecological Restoration

    NASA Astrophysics Data System (ADS)

    Winters, J. M.; Howard, M. S.; Arsuffi, T. L.

    2005-05-01

    The San Marcos River in San Marcos, Hays County, Texas is a biologically unique system with several listed species found in the headwaters. Flowing from the Edwards Aquifer and the second largest spring system in Texas, the water is clear and thermally constant. The physical and biological character of the habitat within and surrounding the river has been severely degraded by human activity. As a means of dealing with the continued disturbance and finding a balance between human needs and conservation, the San Marcos River Habitat Conservation Plan was written as provided by Section 10(a) of the Endangered Species Act. The plan provides habitat mitigation for the fountain darter (Etheostoma fonticola), Comal Springs riffle beetle, (Heterelmis comalensis), and San Marcos salamander (Eurycea nana), while allowing for incidental take resulting from specific restoration and management projects. We used a science-based ecological/experimental approach to address some of the problems and optimize solutions, including restoration of stream banks damaged from overuse, planning for permanent access points and trails, removal of silt deposits caused by extensive flood control structures, wet-pond construction, managing flow, and the control of submerged and emergent non-native vegetation to improve habitat and enhance recreation.

  19. MarcoPolo-R: Near Earth Asteroid Sample Return Mission in ESA assessment study phase

    NASA Astrophysics Data System (ADS)

    Barucci, M. A.; Michel, P.; Cheng, A.; Böhnhardt, H.; Brucato, J. R.; Dotto, E.; Ehrenfreund, P.; Franchi, I. A.; Green, S. F.; Lara, L. M.; Marty, B.; Koschny, D.

    2012-04-01

    MarcoPolo-R is a sample return mission to a primitive Near-Earth Asteroid (NEA) selected in February 2011 for the Assessment Study Phase in the framework of ESA's Cosmic Vision 2 program. MarcoPolo-R is a European-led mission with a proposed NASA contribution. MarcoPolo-R takes advantage of three industrial studies completed as part of the previous Marco Polo mission (see ESA/SRE (2009)3). The aim of the new Assessment Study is to reduce the cost of the mission while maintaining its high science level, on the basis of advanced studies and technologies, optimization of the mission, and consolidation of the collaboration with other partners (NASA, AEB…). The main goal of the MarcoPolo-R mission is to return unaltered NEA material for detailed analysis in ground-based laboratories. The limited sampling provided by meteorites does not offer the most primitive material available in near-Earth space. More primitive material, having experienced less alteration on the asteroid, will be more friable and would not survive atmospheric entry in any discernible amount. Only in Earth laboratories can instruments measure the individual components of the complex mixture of materials that forms an asteroid regolith with the necessary precision and sensitivity to determine their precise chemical and isotopic composition. Such measurements are vital for revealing the evidence of stellar, interstellar medium, pre-solar nebula and parent body processes that are retained in primitive asteroidal material, unaltered by atmospheric entry or terrestrial contamination. It is no surprise therefore that sample return missions are considered a priority by a number of the leading space agencies. MarcoPolo-R will rendezvous with a unique kind of target, a primitive binary NEA, scientifically characterize it at multiple scales, and return a unique pristine sample to Earth unaltered by the atmospheric entry process or terrestrial weathering. The baseline target of MarcoPolo-R is the primitive binary NEA (175706) 1996 FG3, which offers a very efficient operational and technical mission profile. A binary target also provides enhanced science return: the choice of this target will allow new investigations to be performed including those of the fascinating geology and geophysics of asteroids that are impossible to obtain from a single object. Precise measurements of the mutual orbit and rotation state of both components can be used to probe higher-level harmonics of the gravitational potential, and therefore the internal structure. A unique opportunity is offered to study the dynamical evolution driven by the YORP/ Yarkovsky thermal effects. Possible migration of regolith on the primary from poles to equator allows the increasing maturity of asteroidal regolith with time to be expressed as a latitude-dependent trend, with the most-weathered material at the equator matching what is seen in the secondary. MarcoPolo-R will allow us to study the most primitive materials available to investigate early solar system formation processes. Moreover, MarcoPolo-R will provide a sample from a known target with known geological context. Direct investigation of both the regolith and fresh interior fragments is also impossible by any means other than sample return.

  20. Marginal Zone Macrophage Receptor MARCO Is Trapped in Conduits Formed by Follicular Dendritic Cells in the Spleen

    PubMed Central

    Kellermayer, Zoltán; Fisi, Viktória; Mihalj, Martina; Berta, Gergely; Kóbor, József

    2014-01-01

    The marginal zone (MZ) region of the spleen plays an important role in leukocyte traffic and the removal of blood-borne pathogens by resident macrophages. Macrophage receptor with a collagenous structure (MARCO), expressed by MZ macrophages, recognizes several microbial ligands and is also involved in the retention of MZ B cells. Here, we report that MARCO is also associated with follicular dendritic cells (FDCs) in the spleen. In its FDC-associated form MARCO is arranged in 0.3–0.5-μm diameter granular-fibrillar structures with an appearance similar to the white pulp conduit system formed by fibroblastic reticular cells (FRCs), but with different compartment preference. The follicular display of MARCO resists irradiation and requires the presence of both MZ macrophages and differentiated FDCs. The follicular delivery of MARCO is independent from the shuffling of marginal zone B cells, and it persists after clodronate liposome-mediated depletion of MZ macrophages. Our findings thus indicate that MARCO is distributed to both MZ and follicles within the spleen into conduit-like structures, where FDC-bound MARCO may mediate communication between the stromal microenvironments of MZ and follicles. PMID:24670793

  1. The DeMarco factor: interview with a health policy advocate.

    PubMed

    Jernigan, David H

    2010-05-01

    An interview with Vincent DeMarco, President of the Maryland Citizen's Health Initiative, reviews the history and strategies used to win victories for public health on gun policy and tobacco taxes and to seek passage of higher alcohol taxes in the state of Maryland. DeMarco emphasizes the need to build broad coalitions, to engage policy makers at election time and not just or primarily during legislative sessions, and to take advantage of the power of the news media as a microphone for reaching millions of possible supporters. The interview concludes with recommendations for public health training and practitioners in order to become successful policy advocates in a rapidly changing media and political landscape. PMID:20495097

  2. Dr. Marco Marra: Pioneer and Visionary in Cancer Genomics Research | Office of Cancer Genomics

    Cancer.gov

    Dr. Marco Marra is a highly distinguished genomics and bioinformatics researcher. He is the Director of Canada’s Michael Smith Genome Sciences Centre at the BC Cancer Agency and holds a faculty position at the University of British Columbia. The Centre is a state-of-the-art sequencing facility in Vancouver, Canada, with a major focus on the study of cancers.  Many of their research projects are undertaken in collaborations with other Canadian and international institutions.

  3. Uranium series isotopes concentration in sediments at San Marcos and Luis L. Leon reservoirs, Chihuahua, Mexico

    SciTech Connect

    Méndez-García, C.; Montero-Cabrera, M. E.; Renteria-Villalobos, M.; García-Tenorio, R.

    2008-01-01

    Spatial and temporal distribution of the radioisotopes concentrations were determined in sediments near the surface and core samples extracted from two reservoirs located in an arid region close to Chihuahua City, Mexico. At San Marcos reservoir one core was studied, while from Luis L. Leon reservoir one core from the entrance and another one close to the wall were investigated. ²³²Th-series, ²³⁸U-series, ⁴⁰K and ¹³⁷Cs activity concentrations (AC, Bq kg⁻¹) were determined by gamma spectrometry with a high purity Ge detector. ²³⁸U and ²³⁴U ACs were obtained by liquid scintillation and alpha spectrometry with a surface barrier detector. Dating of core sediments was performed applying CRS method to ²¹⁰Pb activities. Results were verified by ¹³⁷Cs AC. Resulting activity concentrations were compared among corresponding surface and core sediments. High ²³⁸U-series AC values were found in sediments from San Marcos reservoir, because this site is located close to the Victorino uranium deposit. Low AC values found in Luis L. Leon reservoir suggest that the uranium present in the source of the Sacramento – Chuviscar Rivers is not transported up to the Conchos River. Activity ratios (AR) ²³⁴U/²³⁸U and ²³⁸U/²²⁶Ra in sediments have values between 0.9–1.2, showing a behavior close to radioactive equilibrium in the entire basin. ²³²Th/²³⁸U, ²²⁸Ra/²²⁶Ra ARs are witnesses of the different geological origin of sediments from San Marcos and Luis L. Leon reservoirs.

  4. MARCO, TLR2, and CD14 are required for macrophage cytokine responses to mycobacterial trehalose dimycolate and Mycobacterium tuberculosis.

    PubMed

    Bowdish, Dawn M E; Sakamoto, Kaori; Kim, Mi-Jeong; Kroos, Mariliis; Mukhopadhyay, Subhankar; Leifer, Cynthia A; Tryggvason, Karl; Gordon, Siamon; Russell, David G

    2009-06-01

    Virtually all of the elements of Mycobacterium tuberculosis (Mtb) pathogenesis, including pro-inflammatory cytokine production, granuloma formation, cachexia, and mortality, can be induced by its predominant cell wall glycolipid, trehalose 6,6'-dimycolate (TDM/cord factor). TDM mediates these potent inflammatory responses via interactions with macrophages both in vitro and in vivo in a myeloid differentiation factor 88 (MyD88)-dependent manner via phosphorylation of the mitogen activated protein kinases (MAPKs), implying involvement of toll-like receptors (TLRs). However, specific TLRs or binding receptors for TDM have yet to be identified. Herein, we demonstrate that the macrophage receptor with collagenous structure (MARCO), a class A scavenger receptor, is utilized preferentially to "tether" TDM to the macrophage and to activate the TLR2 signaling pathway. TDM-induced signaling, as measured by a nuclear factor-kappa B (NF-kappaB)-luciferase reporter assay, required MARCO in addition to TLR2 and CD14. MARCO was used preferentially over the highly homologous scavenger receptor class A (SRA), which required TLR2 and TLR4, as well as their respective accessory molecules, in order for a slight increase in NF-kappaB signaling to occur. Consistent with these observations, macrophages from MARCO(-/-) or MARCO(-/-)SRA(-/-) mice are defective in activation of extracellular signal-related kinase 1/2 (ERK1/2) and subsequent pro-inflammatory cytokine production in response to TDM. These results show that MARCO-expressing macrophages secrete pro-inflammatory cytokines in response to TDM by cooperation between MARCO and TLR2/CD14, whereas other macrophage subtypes (e.g. bone marrow-derived) may rely somewhat less effectively on SRA, TLR2/CD14, and TLR4/MD2. Macrophages from MARCO(-/-) mice also produce markedly lower levels of pro-inflammatory cytokines in response to infection with virulent Mtb. These observations identify the scavenger receptors as essential binding receptors for TDM, explain the differential response to TDM of various macrophage populations, which differ in their expression of the scavenger receptors, and identify MARCO as a novel component required for TLR signaling. PMID:19521507

  5. Protection against inhaled oxidants through scavenging of oxidized lipids by macrophage receptors MARCO and SR-AI/II

    PubMed Central

    Dahl, Morten; Bauer, Alison K.; Arredouani, Mohamed; Soininen, Raija; Tryggvason, Karl; Kleeberger, Steven R.; Kobzik, Lester

    2007-01-01

    Alveolar macrophages (AMs) express the class A scavenger receptors (SRAs) macrophage receptor with collagenous structure (MARCO) and scavenger receptor AI/II (SRA-I/II), which recognize oxidized lipids and provide innate defense against inhaled pathogens and particles. Increased MARCO expression in lungs of ozone-resistant mice suggested an additional role protecting against inhaled oxidants. After ozone exposure, MARCO–/– mice showed greater lung injury than did MARCO+/+ mice. Ozone is known to generate oxidized, proinflammatory lipids in lung lining fluid, such as 5β,6β-epoxycholesterol (β-epoxide) and 1-palmitoyl-2-(9′-oxo-nonanoyl)-glycerophosphocholine (PON-GPC). Intratracheal instillation of either lipid caused substantial neutrophil influx in MARCO–/– mice, but had no effect in MARCO+/+ mice. Normal AMs showed greater uptake in vitro of β-epoxide compared with MARCO–/– AMs, consistent with SRA function in binding oxidized lipids. SR-AI/II–/– mice showed similar enhanced acute lung inflammation after β-epoxide or another inhaled oxidant (aerosolized leachate of residual oil fly ash). In contrast, subacute ozone exposure did not enhance inflammation in SR-AI/II–/– versus SR-AI/II+/+ mice, reflecting increased AM expression of MARCO. These data identify what we believe to be a novel function for AM SRAs in decreasing pulmonary inflammation after oxidant inhalation by scavenging proinflammatory oxidized lipids from lung lining fluids. PMID:17332894

  6. Solar measurements from the Airglow-Solar Spectrometer Instrument (ASSI) on the San Marco 5 satellite

    NASA Technical Reports Server (NTRS)

    Woods, Thomas N.

    1994-01-01

    The analysis of the solar spectral irradiance from the Airglow-Solar Spectrometer Instrument (ASSI) on the San Marco 5 satellite is the focus for this research grant. A pre-print copy of the paper describing the calibrations of and results from the San Marco ASSI is attached to this report. The calibration of the ASSI included (1) transfer of photometric calibration from a rocket experiment and the Solar Mesosphere Explorer (SME), (2) use of the on-board radioactive calibration sources, (3) validation of the ASSI sensitivity over its field of view, and (4) determining the degradation of the spectrometers. We have determined that the absolute values for the solar irradiance needs adjustment in the current proxy models of the solar UV irradiance, and the amount of solar variability from the proxy models are in reasonable agreement with the ASSI measurements. This research grant also has supported the development of a new solar EUV irradiance proxy model. We expected that the magnetic flux is responsible for most of the heating, via Alfen waves, in the chromosphere, transition region, and corona. From examining time series of solar irradiance data and magnetic fields at different levels, we did indeed find that the chromospheric emissions correlate best with the large magnetic field levels.

  7. Uranium in the Surrounding of San Marcos-Sacramento River Environment (Chihuahua, Mexico)

    PubMed Central

    Rentería-Villalobos, Marusia; Cortés, Manuel Reyes; Mantero, Juan; Manjón, Guillermo; García-Tenorio, Rafael; Herrera, Eduardo; Montero-Cabrera, Maria Elena

    2012-01-01

    The main interest of this study is to assess whether uranium deposits located in the San Marcos outcrops (NW of Chihuahua City, Mexico) could be considered as a source of U-isotopes in its surrounding environment. Uranium activity concentrations were determined in biota, ground, and surface water by either alpha or liquid scintillation spectrometries. Major ions were analyzed by ICP-OES in surface water and its suspended matter. For determining uranium activity in biota, samples were divided in parts. The results have shown a possible lixiviation and infiltration of uranium from geological substrate into the ground and surface water, and consequently, a transfer to biota. Calculated annual effective doses by ingestion suggest that U-isotopes in biota could not negligibly contribute to the neighboring population dose. By all these considerations, it is concluded that in this zone there is natural enhancement of uranium in all environmental samples analyzed in the present work. PMID:22536148

  8. Geochemical evaluation of the geothermal resources in the San Marcos region, Guatemala

    USGS Publications Warehouse

    Fournier, R.O.; Hanshaw, B.B.

    1986-01-01

    The chemical and isotopic compositions of hot springs in the San Marcos region of Guatemala are internally consistent with a hydrologic model in which a deep 240??C reservoir and one or more shallow 195-200??C reservoirs are present. Variations in hot-spring water compositions results from a combination of boiling, mixing with cold, dilute water, and chemical re-equilibration with decreasing temperature. The recharge water for the deep 240??C reservoir is isotopically heavier than the local meteoric water and probably comes from many kilometers to the west or southwest. The water in the shallow reservoir is a mixture of the 240??C water with about 20 ?? 5% of cold, locally derived meteoric water. After mixing, the water in the shallow reservoir re-equilibrates with reservoir rock at 195-200??C. In some places additional mixing with cold water occurs after water leaves the shallow reservoir. ?? 1986.

  9. Automation of the Telescope in the Observatory at Texas State University-San Marcos

    NASA Astrophysics Data System (ADS)

    Smith, Cary

    2012-03-01

    The telescope in the Observatory at Texas State University - San Marcos is automated by means of off the shelf parts with a budget of 300.00. This telescope retrofit is to replace obsolete and malfunctioning hardware and update software. The telescope upgrade entailed the removal of all of the timeworn hardware and thorough testing of the motors and encoders to insure proper functionality. From a less expensive telescope a new motor control board is acquired that is capable of performing tasks beyond the capabilities of the old board. A Schmitt Trigger and a set of four capacitors in series are used to lessen the noise produced by the older model motors and encoders. All of the retrofitted hardware is tested to insure proper functionality for the final product before installation into the telescope. After final installation a problem with the communication between software and hardware was found and remedied.

  10. Lifetime predictions for the Solar Maximum Mission (SMM) and San Marco spacecraft

    NASA Technical Reports Server (NTRS)

    Smith, E. A.; Ward, D. T.; Schmitt, M. W.; Phenneger, M. C.; Vaughn, F. J.; Lupisella, M. L.

    1989-01-01

    Lifetime prediction techniques developed by the Goddard Space Flight Center (GSFC) Flight Dynamics Division (FDD) are described. These techniques were developed to predict the Solar Maximum Mission (SMM) spacecraft orbit, which is decaying due to atmospheric drag, with reentry predicted to occur before the end of 1989. Lifetime predictions were also performed for the Long Duration Exposure Facility (LDEF), which was deployed on the 1984 SMM repair mission and is scheduled for retrieval on another Space Transportation System (STS) mission later this year. Concepts used in the lifetime predictions were tested on the San Marco spacecraft, which reentered the Earth's atmosphere on December 6, 1988. Ephemerides predicting the orbit evolution of the San Marco spacecraft until reentry were generated over the final 90 days of the mission when the altitude was less than 380 kilometers. The errors in the predicted ephemerides are due to errors in the prediction of atmospheric density variations over the lifetime of the satellite. To model the time dependence of the atmospheric densities, predictions of the solar flux at the 10.7-centimeter wavelength were used in conjunction with Harris-Priester (HP) atmospheric density tables. Orbital state vectors, together with the spacecraft mass and area, are used as input to the Goddard Trajectory Determination System (GTDS). Propagations proceed in monthly segments, with the nominal atmospheric drag model scaled for each month according to the predicted monthly average value of F10.7. Calibration propagations are performed over a period of known orbital decay to obtain the effective ballistic coefficient. Progagations using plus or minus 2 sigma solar flux predictions are also generated to estimate the despersion in expected reentry dates. Definitive orbits are compared with these predictions as time expases. As updated vectors are received, these are also propagated to reentryto continually update the lifetime predictions.

  11. Planetary protection issues for the MarcoPolo NEO sample return mission

    NASA Astrophysics Data System (ADS)

    Romstedt, Jens; Barucci, M. A.; Yoshikawa, Makoto; Koschny, Detlef; Boehnhardt, Hermann; Brucato, J. R.; Coradini, Marcello; Dotto, Elisabetta; Franchi, Ian A.; Green, Simon F.; Josset, Jean-Luc; Kawagushi, Jun; Michel, Patrick; Muinonen, Karri; Oberst, Juergen; Pillinger, Judith; Prieur, Daniel; Yano, Hajime; Agnolon, David; Binzel, Richard P.

    The MarcoPolo mission has been selected as an M-class candidate for assessment study within the Cosmic Vision 2015-2025 programme of the European Space Agency (ESA). Through a competitive process the final candidate will be selected at the end of the year 2011. The primary goal of this mission is to return samples of material from a Near Earth Object (NEO) to Earth. An automated system will collect material from the top surface layer with a mass of around 100g. The actual sampling sequence is preceded by an intensive mapping and characterisation campaign of the target body by remote sensing instruments on an orbiting spacecraft. The collected material will be transferred to a return capsule that enters Earth's atmosphere and lands. The proposed candidate targets are primitive objects of various spectral classes. In a current process based on scientific evaluation, engineering and programmatic requirements the list of objects will be narrowed down to a short list of prime target bodies. The delivery of alien material to Earth using a spacecraft places this mission in Category V according to COSPAR planetary protection rules. Depending on the target or region of a target the mission is subclassified as "none-restricted" or" restricted" return. The latter implies a severe impact on the complexity of the mission architecture due to much higher technological constraints and sample handling procedures on Earth. Among the NEO population there is a large variety of very different objects. Only a few are assessed on the basis of planetary protection rules. Future small body exploration missions like MarcoPolo require the assessment and categorisation according to the biologic potential of the respective target body. This presentation will assess the proposed mission according to the COSPAR planetary protection rules as adopted by ESA.

  12. Phagocytosis of mycobacteria by zebrafish macrophages is dependent on the scavenger receptor Marco, a key control factor of pro-inflammatory signalling.

    PubMed

    Benard, Erica L; Roobol, Stefan J; Spaink, Herman P; Meijer, Annemarie H

    2014-12-01

    Scavenger receptors on the cell surface of macrophages play an important role in host defence through their ability to bind microbial ligands and induce phagocytosis. Concurrently, signal transduction pathways are initiated that aid in defence mechanisms against the invading microbe. Here we report on the function of scavenger receptor Marco (Macrophage receptor with collagenous structure) during infection of zebrafish embryos with Mycobacterium marinum, a close relative of M. tuberculosis. Morpholino knockdown demonstrates that Marco is required for the rapid phagocytosis of M. marinum following intravenous infection. Furthermore, gene expression analysis shows that Marco controls the initial transient pro-inflammatory response to M. marinum and remains a determining factor for the immune response signature at later stages of infection. Increased bacterial burden following marco knockdown indicates that this scavenger receptor is important for control of M. marinum growth, likely due to delayed phagocytosis and reduced pro-inflammatory signalling observed under conditions of Marco deficiency. PMID:25086293

  13. European asteroid sample return mission: MarcoPolo-R and its future

    NASA Astrophysics Data System (ADS)

    Barucci, M.

    2014-07-01

    MarcoPolo-R is a sample return mission study to a primitive Near-Earth Asteroid (NEA) carried out at ESA from 2008 in the framework of ESA's Cosmic Vision (CV) programme, with the objective to answer to the fundamental CV questions ''How does the Solar System work?'' and ''What are the conditions for life and planetary formation?''. The returned material will allow us to study in terrestrial laboratories some of the most primitive materials available to investigate early solar system formation processes, to explore initial stages of habitable planet formation, to identify and characterize the organics and volatiles in a primitive asteroid. In fact, only in the laboratory can instruments with the necessary precision and sensitivity be applied to individual components of the complex mixture of materials that forms an asteroid regolith, to determine their precise chemical and isotopic composition. Such measurements are vital for revealing the evidence of interstellar medium, pre-solar nebula and parent body processes that are retained in primitive asteroidal material, unaltered by atmospheric entry or terrestrial contamination. In addition to addressing these major science goals, the MarcoPolo-R mission study (ESA/SRE (2013)4) also involved innovative European technologies for which ESA technical development programs are still under way. As a result of the several industrial studies, ESA designed a remarkably cost-effective and robust asteroid sample return mission scenario. The spacecraft has been defined making use of low-cost units for most of the sub-systems. The key sample return capabilities, i.e. asteroid navigation, touch and go, sampling mechanism and the re-entry capsule have reached at ESA a validation status to enter implementation phase. In this new era of international effort and interest of sample return with the selected missions of Hayabusa-2 (JAXA) and OSIRIS-Rex (NASA), the development of sample return technology represents in Europe a crucial element for planetary science and for the space technology development. The status of the mission study at ESA will be presented and the future for European asteroid sample return will be discussed.

  14. Herschel observations of the Marco Polo-R asteroid 175706 (1996 FG3).

    NASA Astrophysics Data System (ADS)

    O'Rourke, L.; Barucci, A.; Gònzalez-Garcìa, B.; Dotto, E.; Küppers, M.

    2012-09-01

    Background: The Marco Polo-R mission has been selected for the assessment study phase of the ESA M3 missions. This ESA-led sample return mission to the binary asteroid 1996 FG3 (launch window between 2020 and 2024) is proposed with a design that allows it to fit within the pre-defined cost cap of a M-class mission. The binary nature of the target will allow more precise measurements of mass, gravity, and density than for a single object, as well as additional insights into the geology and geophysics of the system. The asteroid has been classified by Binzel et al. [1] as a C-type. It is considered to be a typical example of a primitive object [2]. Dynamically, this is an Apollo asteroid with semimajor axis a of 1.054 AU, eccentricity e of 0.35, and and inclination i of 1.98 degrees. Measurements of the albedo derived from thermal infrared observations give a value of pV = 0.042 (+0.035 -0.017), and a combined diameter of D = 1.84 (+0.56 -0.47) km [3]. The Herschel observations : The MACH-11 (Measurements of 11 Asteroids & Comets) Programme observed this binary asteroid in two occasions in November of 2012. The observations performed had a duration of 0.6 hours with the asteroid pair moving rapidly at 6'/hr thus making removal of the background quite straightforward. The observations were performed in two observing blocks; the first block consisted of a 2 repetition blue/red map, the second block consisted of a 2 repetition green/red map, with the intention to observe the target at different phase angles. Our Results : Our measurements will serve to update the known radiometric properties for this binary asteroid through their inclusion into a thermophysical model (TPM) [4] which has been validated against a large database of asteroids including targets of other spacecraft mission e.g. Lutetia [5], Itokawa [6]. Using existing sets of published thermal observations (Spitzer, TNG NICS), combined with our Herschel observations, applied within this thermophysical model, we will derive the radiometric properties of this target pair. The calculations are to be performed for the full range of possible shape and spin-vector solutions derived from the available sample of visual lightcurve observations, taking into account the implications of the asteroid satellites impact on the derived flux. The output of our model will aid in deriving the asteroids thermal inertia, as well as provide important information on the surface properties of this binary asteroid; important due to their relevance in the preparation of the future Marco Polo-R spacecraft.

  15. MarcoPolo-R: Near Earth Asteroid Sample Return Mission candidate as ESA-M3 class mission

    NASA Astrophysics Data System (ADS)

    Michel, Patrick; Lara, Luisa-M.; Marty, Bernard; Koschny, Detlef; Barucci, Maria Antonietta; Cheng, Andy; Bohnhardt, Hermann; Brucato, John R.; Dotto, Elisabetta; Ehrenfreund, Pascale; Franchi, Ian A.; Green, Simon F.

    2015-03-01

    MarcoPolo-R is a sample return mission to a primitive Near-Earth Asteroid (NEA) selected in February 2011 for the Assessment Study Phase at ESA in the framework of ESAfs Cosmic Vision 2 program. MarcoPolo-R is a European-led mission with a proposed NASA contribution. MarcoPolo-R takes advantage of three industrial studies completed as part of the previous Marco Polo mission (see ESA/SRE (2009)3). The aim of the new Assessment Study is to reduce the cost of the mission while maintaining its high science level, on the basis of advanced studies and technologies, as well as optimization of the mission. MarcoPolo-R will rendezvous with a unique kind of target, a primitive binary NEA, scientifically characterize it at multiple scales, and return a unique pristine sample to Earth unaltered by the atmospheric entry process or terrestrial weathering. The baseline target of MarcoPolo-R is the primitive binary NEA (175706) 1996 FG3, which offers a very efficient operational and technical mission profile. A binary target also provides enhanced science return: the choice of this target will allow new investigations to be performed more easily compared to a single object, and also enables investigations of the fascinating geology and geophysics of asteroids that are impossible to obtain from a single object. Precise measurements of the mutual orbit and rotation state of both components can be used to probe higher-level harmonics of the gravitational potential, and therefore the internal structure. A unique opportunity is offered to study the dynamical evolution driven by the YORP/Yarkovsky thermal effects. Possible migration of regolith on the primary from poles to equator allows the increasing maturity of asteroidal regolith with time to be expressed as a latitude-dependent trend, with the most-weathered material at the equator matching what is seen in the secondary. MarcoPolo-R will allow us to study the most primitive materials available to investigate early solar system formation processes. Moreover, MarcoPolo-R will provide a sample from a known target with known geological context. Direct investigation of both the regolith and fresh interior fragments is also impossible by any means other than sample return. The main goal of the MarcoPolo-R mission is to return unaltered NEA material for detailed analysis in ground-based laboratories. The limited sampling provided by meteorites does not offer the most primitive material available in near-Earth space. More primitive material, having experienced less alteration on the asteroid, will be more friable and would not survive atmospheric entry in any discernible amount. Only in the laboratory can instruments with the necessary precision and sensitivity be applied to individual components of the complex mixture of materials that forms an asteroid regolith, to determine their precise chemical and isotopic composition. Such measurements are vital for revealing the evidence of stellar, interstellar medium, pre-solar nebula and parent body processes that are retained in primitive asteroidal material, unaltered by atmospheric entry or terrestrial contamination. It is no surprise therefore that sample return missions are considered a priority by a number of the leading space agencies.

  16. Marcos Zapata's "Last Supper": a feast of European religion and Andean culture.

    PubMed

    Zendt, Christina

    2010-01-01

    In Marcos Zapata's 1753 painting of the Last Supper in Cuzco, Peru, Christian symbolism is filtered through Andean cultural tradition. Zapata was a late member of the Cuzco School of Painting, a group comprised of few European immigrants and handfuls of mestizo and Indian artists. The painters in Cuzco learned mostly from prints of European paintings, and their style tends to blend local culture into the traditional painting of their conquistadors. Imagery was the most successful tool used by the Spaniards in their quest to Christianize the Andean population. By teaching locals to paint Christian subjects, they were able to infuse Christianity into Andean traditions. Zapata's rendering of the Last Supper utilizes this cultural blending while staying true to the Christian symbolism within the subject. Instead of the traditional lamb, Zapata's Last Supper features a platter of cuy, or guinea pig, an Andean delicacy stocked with protein as well as cultural significance. Cuy was traditionally a sacrificial animal at Inca agricultural festivals and in this way it offers poignant parallel to the lamb, as a traditional Christian sacrificial animal. PMID:21568039

  17. Surface Lipoprotein PpiA of Streptococcus mutans Suppresses Scavenger Receptor MARCO-Dependent Phagocytosis by Macrophages ▿

    PubMed Central

    Mukouhara, Tadashi; Arimoto, Takafumi; Cho, Kasei; Yamamoto, Matsuo; Igarashi, Takeshi

    2011-01-01

    Streptococcus mutans is associated with the initiation and progression of human dental caries and is occasionally isolated from the blood of patients with bacteremia and infective endocarditis. For the pathogen to survive in the infected host, surface lipoproteins of S. mutans are likely to play important roles in interactions with the innate immune system. To clarify the role that a putative lipoprotein, peptidyl-prolyl cis/trans-isomerase (PpiA), of S. mutans plays in the macrophage response, we investigated the response of THP-1-derived macrophages to S. mutans challenge. The deletion of the gene encoding Lgt eliminated PpiA on the cell surface of S. mutans, which implies that PpiA is a lipoprotein that is lipid anchored in the cell membrane by Lgt. Human and murine peritoneal macrophages both showed higher phagocytic activities for the ppiA and lgt mutants than the wild type, which indicates that the presence of PpiA reduces S. mutans phagocytosis. In addition, infection with S. mutans markedly induced mRNAs of macrophage receptor with collagenous structure (MARCO) and scavenger receptor A (SR-A) in human macrophages. In particular, transcriptional and translational levels of MARCO in human macrophages infected with the ppiA mutant were higher than those in macrophages infected with the wild type. Phagocytosis of S. mutans by human macrophages markedly decreased after treatment with anti-MARCO IgG. These results demonstrate that the S. mutans lipoprotein PpiA contributes to suppression of MARCO-mediated phagocytosis of this bacterium by macrophages. PMID:21986627

  18. FANTINA: Fathom Asteroids Now: Tomography and Imagery of a NEA- Payload For Marco Polo R CV3 / ESA mission

    NASA Astrophysics Data System (ADS)

    Herique, A.; Biele, J.; Bousquet, P.; Ciarletti, V.; Ho, T. M.; Issler, J. L.; Kofman, W.; Michel, P.; Plettemeier, D.; Puget, P.; Souyris, J. C.; Ulamec, S.; van Zoest, T.; Zine, S.

    2012-04-01

    The internal structure of small bodies is still poorly known and has never been measured directly. There is no way to determine from ground based observation whether the body is a monolithic piece of rock or a rubble-pile, an aggregate of boulders held together by gravity and how much porosity it contains, both in the form of micro-scale or macro-scale porosity. Knowing this structure is a key point for a better understanding of the asteroid accretion and dynamical evolution. It is the main objective of the FANTINA experience proposed Payload for Marco Polo R CV3 / ESA mission: FANTINA (Marco Polo's Daughter) for Fathom Asteroids Now: Tomography and Imagery of a NEA is to provide measurement capabilities and science data which are not accessible by remote sensing of the asteroid from the Marco-Polo R spacecraft alone and which complement the analysis of the returned samples. The FANTINA payload is a Lander carrying the ASSERT experiment and a complementary payload to be defined: ASSERT is a bistatic CONSERT/Rosetta-like radar to achieve the tomography both in transmission and in reflexion of the asteroid in order to characterise its composition and its heterogeneity from decimetric to global scale. The lander is a long-lived bus in the 10-kg class derived from MASCOT/Hayabusa 2. This paper reviews the science rationale of FANTINA in the context of the Marco Polo R mission to 1996FG3. The surface package concept will be reviewed including the radar tomography principles. So a preliminary design and budget will be done.

  19. Telescience with MARCO/HOLOP on board the spacelab D2-mission as a preparation for Columbus

    NASA Astrophysics Data System (ADS)

    Bennett, E.; Geist, W.; Heimann, K.; Heyland, D.; Hibsch, G.; Schmidt, K. D.

    The implementation of the telescience concept and its test in precursor missions is mandatory for experiment operations in the Columbus era with respect to enhancements in science quality and quantity. During the German D2 Spacelab mission, scheduled for spring 1993, a fluid physics experiment (MARCO, MARangoni COnvection in an open boat) will be performed in the telescience mode, using the HOLOP-D2 (HOLographic OPtics laboratory) experiment facility. MARCO will be remotely operated by the experimenter from a USOC (User Support and Operations Center). DLR/MUSC (Microgravity User Support Center, located at Cologne, Germany) will play the role of this USOC, being connected to DLR/GSOC (German Space Operations Center, located in Oberpfaffenhofen, Germany) via remote data, voice and video lines. Telescience with MARCO/HOLOP is a joint effort between DARA GmbH (Deutsche Agentur für Raumfahrt-Angelegenheiten), DLR (Deutsche Forschungsanstalt für Luft- und Raumfahrt e.V.) and ESA (European Space Agency).

  20. Behavioral and physiological antipredator responses of the San Marcos salamander, Eurycea nana.

    PubMed

    Davis, Drew R; Gabor, Caitlin R

    2015-02-01

    Exposure to predatory stimuli typically results in the elevation of circulating glucocorticoid levels and a behavioral response of freezing or escape behavior in many prey species. Corticosterone (CORT) is the main glucocorticoid in amphibians and is known to be important in modulating many behaviors and developmental functions. The federally threatened San Marcos salamander, Eurycea nana, decreases activity in response to both native and introduced predatory fish, however, experience may further influence these interactions. To better understand the indirect effects of fish predators on this salamander, we examined both the antipredator behavior and water-borne CORT release rates in response to chemical cues (kairomones) from two fish species that varied in temporal risk of predation: (1) a low encounter frequency predator (largemouth bass, Micropterus salmoides), (2) a high encounter frequency predator (redbreast sunfish, Lepomis auritus), and (3) a blank water control. Salamanders reduced activity (antipredator response) after exposure to both predator treatments, but not to the blank water control, and the response to M. salmoides was significantly stronger than that to L. auritus. The CORT response (post-stimulus/pre-stimulus release rates) did not differ between the blank water control and L. auritus treatments, and both were significantly less than the CORT response to M. salmoides. Overall, E. nana showed a decreased antipredator response and no CORT response towards the high encounter frequency L. auritus as compared to the low encounter frequency M. salmoides. Eurycea nana may mute antipredator and CORT responses to high temporal frequency predators. There was, however, no correlation between CORT release rates and antipredator behavior, which suggests that the presence of predators may be affecting CORT response and behavior independently. PMID:25446225

  1. CAMAM instrument suite for MarcoPolo-R mission to an asteroid

    NASA Astrophysics Data System (ADS)

    Tulej, Marek; Riedo, Andreas; Neuland, Maike; Meyer, Stefan; Wurz, Peter; Thomas, Nicolas

    2013-04-01

    CAMAM (Composition And Morphology of Asteroid's Material) is an analytical instrument suite developed for investigation of composition and morphology of asteroidal matter for the MarcoPolo-R sample return mission from a primitive near-Earth asteroid. The instrument combines a microscope-camera system (MCS), a laser ablation time-of-flight mass spectrometer (LMS), and a regolith particle trap (PT). PT uses a charged metallic foil to attract mm-sized or smaller regolith particles from a dust cloud that will be lifted up during the sampling phase. A translational mechanism will deliver the samples to the measurement location inside the CAMAM instrument. CAMAM will conduct measurements by complementary methodologies in a symbiotic way and will allow characterisation of regolith samples by optical investigation and mass spectrometry. MCS will identify and characterise sample components, such as chondrules, matrix, refractory inclusions, down to individual micro-metre-sized grains and particles. Surface features larger than a few µm will be characterised by multicolour imagery, imagery of fluorescence induced by UV sample irradiation, and polarisation analysis of light reflected from the surface. The microscope will yield structural details and morphology of a sample including sample shape, size and texture. Investigation of optical spectral properties of the sample surface will also provide an insight to surface mineralogy and help in identification of organic compound deposits. LMS will conduct measurements of the elemental composition of a sample down to a level of ppm, the isotopic distribution of elements, and also will investigate the molecular compounds that are located on the sample surface. CAMAM studies will allow a comprehensive investigation of the interrelationship between grains, their structure, chemical composition, mineralogy, and adsorbed molecules. We will discuss concepts underlying CAMAM instrument operation and demonstrate instrumental performance. References 1) N. Thomas et al., "The microscope for Beagle 2", Planet. Sp. Sci., 52, pp. 853—866, 2004. 2) U. Rohner, J. Whitby, and P. Wurz, "A miniature laser ablation time-of-flight mass spectrometer for in situ planetary exploration", Meas. Sci. Technol., 14, pp. 2159—2164, 2003. 3) M. Tulej, M. Iakovleva, I. Leya, and P. Wurz, "A miniature mass analyser for in situ elemental analysis of planetary material - performance studies", Anal. and Bioanal. Chem. 399, pp. 2185—2200, 2011. 4) A. Riedo, A. Bieler, M. Neuland, M. Tulej, and P. Wurz, "Performance evaluation of a miniature laser ablation time-of-flight mass spectrometer designed for in situ investigations in planetary space research", J. Mass. Spectrom., 2013, DOI 10.1002/jms.3104.

  2. Macrophage receptor with collagenous structure (MARCO) is a dynamic adhesive molecule that enhances uptake of carbon nanotubes by CHO-K1 Cells

    SciTech Connect

    Hirano, Seishiro; Fujitani, Yuji; Furuyama, Akiko; Kanno, Sanae

    2012-02-15

    The toxicity of carbon nanotubes (CNTs), a highly promising nanomaterial, is similar to that of asbestos because both types of particles have a fibrous shape and are biopersistent. Here, we investigated the characteristics of macrophage receptor with collagenous structure (MARCO), a membrane receptor expressed on macrophages that recognizes environmental or unopsonized particles, and we assessed whether and how MARCO was involved in cellular uptake of multi-walled CNTs (MWCNTs). MARCO-transfected Chinese hamster ovary (CHO-K1) cells took up polystyrene beads irrespective of the particle size (20 nm–1 μm). In the culture of MARCO-transfected CHO-K1 cells dendritic structures were observed on the bottom of culture dishes, and the edges of these dendritic structures were continually renewed as the cell body migrated along the dendritic structures. MWCNTs were first tethered to the dendritic structures and then taken up by the cell body. MWCNTs appeared to be taken up via membrane ruffling like macropinocytosis, rather than phagocytosis. The cytotoxic EC{sub 50} value of MWCNTs in MARCO-transfected CHO-K1 cells was calculated to be 6.1 μg/mL and transmission electron microscopic observation indicated that the toxicity of MWCNTs may be due to the incomplete inclusion of MWCNTs by the membrane structure. -- Highlights: ►Carbon nanotubes (CNTs) were tethered to MARCO in vitro. ►CNTs were taken up rapidly into the cell body via MARCO by membrane ruffling. ►The incomplete inclusion of CNTs by membranes caused cytotoxicity.

  3. Origin and characteristics of discharge at San Marcos Springs based on hydrologic and geochemical data (2008–10), Bexar, Comal, and Hays Counties, Texas

    USGS Publications Warehouse

    Musgrove, MaryLynn; Crow, Cassi L.

    2012-01-01

    The Edwards aquifer in south-central Texas is a productive and important water resource. Several large springs issuing from the aquifer are major discharge points, popular locations for recreational activities, and habitat for threatened and endangered species. Discharges from Comal and San Marcos Springs, the first and second largest spring complexes in Texas, are used as thresholds in groundwater management strategies for the Edwards aquifer. Comal Springs is generally understood to be supplied by predominantly regional groundwater flow paths; the hydrologic connection of San Marcos Springs with the regional flow system, however, is less understood. During November 2008–December 2010, a hydrologic and geochemical investigation of San Marcos Springs was conducted by the U.S. Geological Survey (USGS) in cooperation with the San Antonio Water System. The primary objective of this study was to define and characterize sources of discharge from San Marcos Springs. During this study, hydrologic conditions transitioned from exceptional drought (the dry period, November 1, 2008 to September 8, 2009) to wetter than normal (the wet period, September 9, 2009 to December 31, 2010), which provided the opportunity to investigate the hydrogeology of San Marcos Springs under a wide range of hydrologic conditions. Water samples were collected from streams, groundwater wells, and springs at and in the vicinity of San Marcos Springs, including periodic (routine) sampling (every 3–7 weeks) and sampling in response to storms. Samples were analyzed for major ions, trace elements, nutrients, and selected stable and radiogenic isotopes (deuterium, oxygen, carbon, strontium). Additionally, selected physicochemical properties were measured continuously at several sites, and hydrologic data were compiled from other USGS efforts (stream and spring discharge). Potential aquifer recharge was evaluated from local streams, and daily recharge or gain/loss estimates were computed for several local streams. Local rainfall and recharge events were compared with physicochemical properties and geochemical variability at San Marcos Springs, with little evidence for dilution by local recharge.

  4. The Cretaceous sediment-hosted copper deposits of San Marcos (Coahuila, Northeastern Mexico): An approach to ore-forming processes

    NASA Astrophysics Data System (ADS)

    García-Alonso, Donají; Canet, Carles; González-Partida, Eduardo; Villanueva-Estrada, Ruth Esther; Prol-Ledesma, Rosa María; Alfonso, Pura; Caballero-Martínez, Juan Antonio; Lozano-Santa Cruz, Rufino

    2011-04-01

    In the San Marcos ranges of Cuatrociénegas, NE Mexico, several sediment-hosted copper deposits occur within the boundary between the Coahuila Block, a basement high mostly granitic in composition and Late Paleozoic to Triassic in age, and the Mesozoic Sabinas rift basin. This boundary is outlined by the regional-scale synsedimentary San Marcos Fault. At the basin scale, the copper mineralization occurs at the top of a ˜1000 m thick red-bed succession (San Marcos Formation, Berrisian), a few meters below a conformable, transitional contact with micritic limestones (Cupido Formation, Hauterivian to Aptian). It consists of successive decimeter-thick roughly stratiform copper-rich horizons placed just above the red-beds, in a transitional unit of carbonaceous grey-beds grading to micritic limestones. The host rocks are fine- to medium-grained arkoses, with poorly sorted and subangular to subrounded grains. The detrital grains are cemented by quartz and minor calcite; besides, late iron oxide grain-coating cement occurs at the footwall unmineralized red-beds. The source area of the sediments, indicated by their modal composition, is an uplifted basement. The contents of SiO 2 (40.70-87.50 wt.%), Al 2O 3 (5.91-22.00 wt.%), K 2O (3.68-12.50 wt.%), Na 2O (0.03-2.03 wt.%) and CaO (0.09-3.78 wt.%) are within the ranges expected for arkoses. Major oxide ratios indicate that the sedimentary-tectonic setting was a passive margin. The outcropping copper mineralization essentially consists in a supergene assemblage of chrysocolla, malachite and azurite. All that remains of the primary mineralization are micron-sized chalcocite grains shielded by quartz cement. In addition, pyrite subhedral grains occur scattered throughout the copper-mineralized horizons. In these weathered orebodies copper contents range between 4.24 and 7.72 wt.%, silver between 5 and 92 ppm, and cobalt from 8 to 91 ppm. Microthermometric measurements of fluid inclusions in quartz and calcite crystals from footwall barren veinlets gave temperatures of homogenization between 98 °C and 165 °C, and ice-melting temperatures between -42.5 °C and -26.1 °C. The primary copper mineralization formed during the early diagenesis, contemporary with the active life of the Sabinas Basin. The mineralizing fluids were dense, near neutral, moderately oxidized brines that originally formed from seawater that, driven by gravity, infiltrated to the deepest parts of the basin and dissolved evaporites. As a result, they became hydrothermal fluids of moderate temperature capable of leaching high amounts of copper. The source of this metal could be mafic detrital grains and iron oxides of the underlying Jurassic and Lower Cretaceous red-beds. Copper precipitation took place when the brines passed through the redox boundary marked by the transition from red- to grey-beds. The upward movement of the brines was promoted by a high heat flow that allowed their convective circulation and their ascent along the synsedimentary San Marcos Fault.

  5. Arecibo and Goldstone Radar Observations of Binary Near-Earth Asteroid and Marco Polo-R Mission Target (175706) 1996 FG3

    NASA Astrophysics Data System (ADS)

    Benner, L. A. M.; Brozovic, M.; Giorgini, J. D.; Lawrence, K. J.; Taylor, P. A.; Nolan, M. C.; Howell, E. S.; Busch, M. W.; Margot, J. L.; Naidu, S. P.; Magri, C.; Shepard, M. K.

    2012-05-01

    We report Arecibo (2380 MHz), 13-cm) and Goldstone (8560 MHz, 3.5-cm) delay-Doppler radar observations of binary near-Earth asteroid and Marco Polo-R mission target (175706) 1996 FG3 that were obtained on nine dates November-December, 2011.

  6. Malaria eradication in Mexico: Some historico-parasitological views oncold war, deadly fevers by Marcos Cueto, Ph.D

    PubMed Central

    Malagón, Filiberto

    2008-01-01

    This review of Professor Marcos Cueto's Cold War Deadly Fevers: Malaria Eradication in Mexico, 1955–1975 discusses some of the historical, sociological, political and parasitological topics included in Dr. Cueto's superbly well-informed volume. The reviewer, a parasitologist, follows the trail illuminated by Dr. Cueto through the foundations of the malaria eradication campaign; the release in Mexico of the first postage stamp in the world dedicated to malaria control; epidemiological facts on malarial morbidity and mortality in Mexico when the campaign began; the emergence of problem areas that impeded eradication; considerations on mosquitoes and malaria transmission in Mexico; the role of business and society in malaria eradication; the results of the campaign; the relationship between malaria and poverty; and the parasitological lessons to be learned from the history of malaria eradication campaigns. Dr. Cueto's excellent and well-informed exploration of malaria – not merely as a disease but as a social, economic and human problem – makes this book required reading.

  7. Surface processes in microgravity for landing and sampling site selection of asteroid missions-Suggestions for MarcoPolo-R

    NASA Astrophysics Data System (ADS)

    Kereszturi, Akos

    2014-10-01

    Surface properties of small asteroids are reviewed in this work focusing on microgravity related processes in order to give constrains for targeting sample acquisition by next missions, especially for MarcoPolo-R proposed by ESA. Based on our current knowledge and the planned capabilities of this mission, good chance exists to get answers for the following basic questions. Formation method of nanophase iron and amorphous ingredients in the regolith could be determined, surface particle size and regolith density estimation would also be gained, and with extrapolation to the rest of the surface, knowledge on transport processes, ages and results of cratering under special gravity-strength regime will be improved. Searching for fresh material on asteroid surface in general requires sophisticated effort, as small craters often do not produce much ejecta in microgravity, but the bright annuli around them could be the result of local surface disturbance, while slopes often exhibit fresh material. To identify these locations high albedo, bluer colour and occasionally the depth of 1 μm absorption band could be useful as they often change parallel to each other. To identify the best area for sample acquisition addresses a strategic question: while smooth terrains with easy navigation and sample acquisition provide strongly weathered fine grains; steeper terrains give access to less weathered, material more representative for the whole asteroid, but navigation and mechanical sampling rise difficulties there.

  8. DNA Microarray Analysis of Submandibular Glands in IgG4-Related Disease Indicates a Role for MARCO and Other Innate Immune-Related Proteins.

    PubMed

    Ohta, Miho; Moriyama, Masafumi; Maehara, Takashi; Gion, Yuka; Furukawa, Sachiko; Tanaka, Akihiko; Hayashida, Jun-Nosuke; Yamauchi, Masaki; Ishiguro, Noriko; Mikami, Yurie; Tsuboi, Hiroto; Iizuka-Koga, Mana; Kawano, Shintaro; Sato, Yasuharu; Kiyoshima, Tamotsu; Sumida, Takayuki; Nakamura, Seiji

    2016-02-01

    IgG4-related disease (IgG4-RD) is a novel systemic disease entity characterized by elevated serum IgG4 and tissue infiltration of IgG4-positive plasma cells accompanied by severe fibrosis. Although recent studies demonstrated that innate immune cells including monocytes and macrophages might promote local fibrosis and IgG4 production, the pathological mechanism remains unclear. In this study, we sought to identify the disease-associated genes, especially innate immune molecules.Gene expression was analyzed by DNA microarray in submandibular glands (SMGs) from patients with IgG4-RD (n = 5), chronic sialoadenitis (CS) (n = 3), and controls (n = 3). Differentially expressed genes (DEGs) were validated by real-time polymerase chain reaction (PCR) and immunohistochemical staining in IgG4-RD (n = 18), CS (n = 4), Sjögren syndrome (n = 11), and controls (n = 10).Gene expression patterns in the 3 groups were quite different from each other by the pvclust method and principal components analysis. In IgG4-RD, 1028 upregulated genes and 692 downregulated genes were identified as DEGs (P < 0.05). Gene Ontology (GO) term analysis indicated that the upregulated DEGs in IgG4-RD encoded proteins involved in T/B cell activation and chemotaxis. PCR validated significantly higher expression of macrophage receptor with collagenous structure (MARCO), a pattern-recognition receptor, in IgG4-RD compared with the other groups (P < 0.01). Immunohistochemical analysis confirmed that the expression pattern of MARCO was similar to that of the M2 macrophage marker CD163.MARCO was identified as a disease-associated molecule in IgG4-RD by DNA microarray. Moreover, M2 macrophages might contribute to the initiation of IgG4-RD via MARCO. PMID:26886650

  9. The San Marcos Pueblo Archaeological Site: A Review and Update of Ongoing Work by the Summer of Applied Geophysical Experience (SAGE)

    NASA Astrophysics Data System (ADS)

    Poje, M. S. L.; Berry, K.; Brandt, T. W.; Irwin, T. C.; Creighton, A.; MacLennan, K. J.; Ferguson, J. F.; Pellerin, L.

    2014-12-01

    The San Marcos Pueblo, one of the largest and most important cities of the pre-European Southwest, has long been a place of curiosity for archaeologists and geophysicists alike. Despite numerous archaeological investigations, primarily test excavations and surface surveys carried out at San Marcos from the early 1900s to the present, the site retains pottery sherds scattered along the surface from when it was first occupied in the thirteenth century to its abandonment during the Pueblo Revolt of 1680. Geophysical investigations have identified locations of kivas (ceremonial pits), middens (trash heaps), room blocks and possible metallurgy activity in the area. The site is located south of Santa Fe, NM and to the east of the Cerrillos Hills, a source for lead ore and turquoise. The students of SAGE have studied the San Marcos Pueblo for the past 11 years, and produced a map of the northeastern portion of the Pueblo colloquially called 'El Mapa Grande.' Ground penetrating radar (GPR), magnetics, and electromagnetic (EM) data were acquired on 30mx30m grids and seismic refraction data on various profiles throughout El Mapa Grande. During the 2014 field season new GPR data were acquired on two grids, magnetics data on one, and multiple grids were resurveyed with magnetics and EM to enhance resolution. The most recent GPR data extend coverage of two large anomalies that are part of linear EW-trending structures previously identified and consistent with a possible block wall or midden. Low GPR scatter and circular magnetic lows define several kivas. A target area in the NE of El Mapa Grande was thought to be related to metallurgic activity. Analysis of previous seismic data did not resolve any subsurface features corresponding to a metallurgy operation, but detected the magnetically-chaotic Ancha formation. Comparison with magnetic profile data support the interpretation that this anomaly is caused by a sub-crop of the Ancha Formation.

  10. A new Eimeria sP. from the plumbeous Central American caecilian, Dermophis mexicanus (amphibia: gymnophiona) from Volcán Tajumulco, Department of San Marcos, Guatemala.

    PubMed

    Asmundsson, I M; Campbell, J A; Duszynski, D W

    2000-04-01

    Fresh fecal samples from 5 caecilians (Dermophis mexicanus) were collected and examined for coccidia in the summer of 1998. The caecilians were collected in the Department of San Marcos, Guatemala. Two of the 5 (40%) specimens of caecilians contained an Eimeria species that is described here as new. This represents the first coccidia described from a gymnophionian host. Sporulated oocysts are spheroidal to subspheroidal, 19.5 X 17.7 (16-23 x 15-21) microm, micropyle and oocyst residuum are absent, and 3 (or more) polar granules are always present. Sporocysts are ovoidal, 11.0 X 7.2 (10-12 x 6-9); a Stieda body and sporocyst residuum are present. PMID:10780555

  11. The Marianas-San Marcos vein system: characteristics of a shallow low sulfidation epithermal Au-Ag deposit in the Cerro Negro district, Deseado Massif, Patagonia, Argentina

    NASA Astrophysics Data System (ADS)

    Vidal, Conrado Permuy; Guido, Diego M.; Jovic, Sebastián M.; Bodnar, Robert J.; Moncada, Daniel; Melgarejo, Joan Carles; Hames, Willis

    2016-01-01

    The Cerro Negro district, within the Argentinian Deseado Massif province, has become one of the most significant recent epithermal discoveries, with estimated reserves plus resources of ˜6.7 Moz Au equivalent. The Marianas-San Marcos vein system contains about 70 % of the Au-Ag resources in the district. Mineralization consists of Upper Jurassic (155 Ma) epithermal Au- and Ag-rich veins of low to intermediate sulfidation style, hosted in and genetically related to Jurassic intermediate composition volcanic rocks (159-156 Ma). Veins have a complex infill history, represented by ten stages with clear crosscutting relationships that can be summarized in four main episodes: a low volume, metal-rich initial episode (E1), an extended banded quartz episode with minor mineralization (E2), a barren waning stage episode (E3), and a silver-rich late tectonic-hydrothermal episode (E4). The first three episodes are interpreted to have formed at the same time and probably from fluids of similar composition: a 290-230 °C fluid dominated by meteoric and volcanic waters (-3‰ to -0‰ δ18Owater), with <3 % NaCl equivalent salinity and with a magmatic source of sulfur (-1 to -2 ‰ δ34Swater). Metal was mainly precipitated at the beginning of vein formation (episode 1) due to a combination of boiling at ˜600 to 800 m below the paleowater table, and associated mixing/cooling processes, as evidenced by sulfide-rich bands showing crustiform-colloform quartz, adularia, and chlorite-smectite banding. During episodes 2 and 3, metal contents progressively decrease during continuing boiling conditions, and veins were filled by quartz and calcite during waning stages of the hydrothermal system, and the influx of bicarbonate waters (-6 to -8.5 ‰ δ18Owater). Hydrothermal alteration is characterized by proximal illite, adularia, and silica zone with chlorite and minor epidote, intermediate interlayered illite-smectite and a distal chlorite halo. This assemblage is in agreement with measured fluid inclusion temperatures. A striking aspect of the Marianas-San Marcos vein system is that the high-grade/high-temperature veins are partially covered by breccia and volcaniclastic deposits of acidic composition, and are spatially associated with hot spring-related deposits and an advanced argillic alteration blanket. A telescoped model is therefore proposed for the Marianas-San Marcos area, where deeper veins were uplifted and eroded, and then partially covered by non-explosive, post-mineral rhyolitic domes and reworked volcaniclastic deposits, together with shallow geothermal features. The last tectonic-hydrothermal mineralization episode (E4), interpreted to have formed at lower temperatures, could be related to this late tectonic and hydrothermal activity.

  12. Deployment of a lander on the binary asteroid (175706) 1996 FG3, potential target of the european MarcoPolo-R sample return mission

    NASA Astrophysics Data System (ADS)

    Tardivel, Simon; Michel, Patrick; Scheeres, Daniel J.

    2013-08-01

    The idea of deploying a lander on the secondary body of the binary primitive asteroid (175706) 1996 FG3 is investigated. 1996 FG3 is the backup target of the European sample return space mission MarcoPolo-R under assessment study at the European Space Agency in the framework of the M3 Medium-Class mission competition. The launch will take place in 2022-2024, depending on its selection at the end of 2013. A lander is indicated as an optional payload, depending on mass availability on the spacecraft. Obviously, the possible complexity of a lander deployment is also an important parameter to take into account. Here we demonstrate that, considering worst case scenarios and low requirements on the spacecraft GNC and deployment mechanism, the operations are easy to implement and safe for the main spacecraft. The concept of operations is to deploy a light lander from the L2 Lagrange point of the binary system, on a ballistic trajectory that will impact the secondary asteroid. The fundamental principles of this strategy are briefly presented and a detailed model of 1996 FG3 is considered, to which the strategy is applied. We show that the deployment is successful in 99.94% of cases.

  13. The supplemental instruction program: Student perceptions of the learning environment and impact on student academic achievement in college science at California State University, San Marcos

    NASA Astrophysics Data System (ADS)

    Hizer, Suzanne Elizabeth

    Higher education in science has been criticized and calls to increase student learning and persistence to degree has been recognized as a national problem by the Department of Education, the National Science Foundation, the National Research Council, and the National Academy of Sciences. One mode of academic assistance that may directly address this issue is the implementation of Supplemental Instruction (SI) in science courses. SI is a specific model of academic assistance designed to help students in historically difficult science classes master course content, thus increasing their academic achievement and retention. This study assessed the SI program at California State University, San Marcos, in supported science courses. Specifically, academic achievement based on final course grades were compared between SI participating and nonparticipating students, multiple affective factors were measured at the beginning and end of the semester, and students' perceptions of the classroom and SI session learning environments recorded. Overall, students who attended five or more SI sessions achieved higher final course grades. Students who chose to participate in SI had higher initial levels of responsibility and anxiety. Additionally, SI participants experienced a reduction in anxiety over the semester whereas nonparticipants experienced an increase in anxiety from beginning to the end of the semester. The learning environment of SI embodies higher levels of constructivist principles of active learning such as cooperation, cohesiveness, innovation, and personalization---with one exception for the physics course, which is a based on problem-based learning. Structural equation modeling of variables indicates that high self-efficacy at the end of the semester is directly related to high final course grades; this is mediated by cohesion in the classroom and the cooperation evidenced in SI sessions. These findings are elaborated by student descriptions of what happened in SI sessions and discussed given the theoretical frameworks of Bandura's concept of self-efficacy and learning environment activities that embody constructivist principles.

  14. Arecibo and Goldstone Radar Observations of Binary Near-Earth Asteroid and Marco Polo-R Mission Target (175706) 1996 FG3

    NASA Astrophysics Data System (ADS)

    Benner, Lance A. M.; Brozovic, M.; Giorgini, J. D.; Lawrence, K. J.; Taylor, P. A.; Nolan, M. C.; Howell, E. S.; Busch, M. W.; Margot, J.; Naidu, S. P.; Magri, C.; Shepard, M. K.

    2012-10-01

    We report Arecibo (2380 MHz), 13-cm) and Goldstone (8560 MHz, 3.5-cm) delay-Doppler radar observations of binary near-Earth asteroid and Marco Polo-R mission target (175706) 1996 FG3 that were obtained on nine dates between November 6-December 17, 2011. The images achieve resolutions as fine as 75 m in range and place hundreds of pixels on the primary. The images provide thorough rotational coverage by the primary and reveal a rounded, slightly elongated object with a visible extent of 0.9 km. If the visible extent is about ½ of the actual extent, which would be true for a sphere, then the equatorial diameter is about 1.8 km. The primary has features along its leading edge that resemble the signature of the pronounced ridge on the equator of binary asteroid (66391) 1999 KW4. The images sample a wide range of orbital positions by the secondary, resolve it in range and Doppler frequency, show that it is elongated and roughly 500 m in diameter, and suggest that its rotation is synchronous (or nearly so) with the orbital period of 16.1 h estimated by Scheirich and Pravec (2009, Icarus 200, 531-547). We observe a maximum range separation of 2.5 km that, combined with the nearly circular eccentricity found by Scheirich and Pravec from inversion of lightcurves, establishes a lower bound on the semimajor axis. 1996 FG3 has a circular polarization ratio SC/OC = 0.34±0.02 that is comparable to that of 25143 Itokawa (0.28±0.04), suggesting similar degrees of near-surface roughness. The radar data will yield a 3D model of the primary, possibly a coarse-resolution model of the secondary, more precise orbit fitting, and estimates of the system’s mass and bulk density.

  15. Las propiedades de las estrellas extrañas en el marco de una nueva ecuación de estado para la materia extraña

    NASA Astrophysics Data System (ADS)

    Lugones, G.; Benvenuto, O. G.

    Se estudian las propiedades generales de las estrellas constituídas por materia extraña (ME) en el marco de una nueva ecuación de estado (EOS) en la que consideramos la masa de los quarks como dependiente del número medio de bariones por unidad de volumen. Se asume esta dependencia de forma que los quarks sean livianos (pesados) a densidades altas (bajas). En esta aproximación, la EOS de la ME es similar a la predicha por el modelo de la Bolsa del MIT, pero es significativamente mas dura a bajas densidades. Esta propiedad modifica las propiedades de las estrellas extrañas en forma notable. Encontramos que, con esta nueva EOS, los objetos pueden ser más masivos que en el caso de la EOS de la bolsa del MIT y que, además, pueden presentar mayores redshifts gravitatorios en hasta un 10%. En el caso de las oscilaciones radiales de estos objetos, calculamos la relación período vs. redshift gravitacional y encontramos una expresión analítica simple para el caso de las oscilaciones de objetos de baja masa. Encontramos que, aún con hipótesis muy diferentes en cuanto a la ecuación de estado de la materia extraña, las propiedades generales de estos objetos no se ve afectada en forma fundamental, y, por lo tanto, no deberían ser muy diferentes de las aquí expuestas.

  16. Concentrations of urinary 8-hydroxy-2'-deoxyguanosine and 8-isoprostane in women exposed to woodsmoke in a cookstove intervention study in San Marcos, Peru.

    PubMed

    Commodore, Adwoa A; Zhang, Junfeng Jim; Chang, Yan; Hartinger, Stella M; Lanata, Claudio F; Mäusezahl, Daniel; Gil, Ana I; Hall, Daniel B; Aguilar-Villalobos, Manuel; Vena, John E; Wang, Jia-Sheng; Naeher, Luke P

    2013-10-01

    Nearly half of the world's population is exposed to household air pollution (HAP) due to long hours spent in close proximity to unvented cooking fires. The effect of woodsmoke exposure on oxidative stress was examined by investigating the association between woodsmoke exposure and biomarkers of DNA oxidation (8-hydroxy-2'-deoxyguanosine [8-OHdG]) and lipid peroxidation (8-isoprostane) among control and intervention stove users. HAP exposure assessment was conducted within the framework of a community-randomized controlled trial of 51 communities in San Marcos Province, Cajamarca Region, Peru. The first morning urine voids after 48h HAP exposure assessment from a subset of 45 control and 39 intervention stove users were analyzed for 8-OHdG and 8-isoprostane. General linear models and correlation analyses were performed. Urinary oxidative stress biomarkers ranged from 11.2 to 2270.0μg/g creatinine (median: 132.6μg/g creatinine) for 8-OHdG and from 0.1 to 4.5μg/g creatinine (median: 0.8μg/g creatinine) for 8-isoprostane among all study subjects (n=84). After controlling for the effects of traffic in the community and eating food exposed to fire among all subjects, cooking time was weakly, but positively associated with urinary 8-OHdG (r=0.29, p=0.01, n=80). Subjects' real-time personal CO exposures were negatively associated with 8-OHdG, particularly the maximum 30-second CO exposure during the sampling period (r=-0.32, p=0.001, n=73). 48h time integrated personal PM2.5 was negatively, but marginally associated with urinary 8-isoprostane (r=-0.21, p=0.09, n=69) after controlling for the effect of distance of homes to the road. Urinary 8-isoprostane levels reported in the available literature are comparable to results found in the current study. However there were relatively high levels of urinary 8-OHdG compared to data in the available literature for 8-OHdG excretion. Results suggest a sustained systemic oxidative stress among these Peruvian women chronically exposed to wood smoke. PMID:24041735

  17. Concentrations of Urinary 8-Hydroxy-2′-deoxyguanosine and 8-isoprostane in Women Exposed to Woodsmoke in a Cookstove Intervention Study in San Marcos, Peru

    PubMed Central

    Commodore, Adwoa A.; Zhang, Junfeng (Jim); Chang, Yan; Hartinger, Stella M.; Lanata, Claudio F.; Mäusezahl, Daniel; Gil, Ana I.; Hall, Daniel B.; Aguilar-Villalobos, Manuel; Vena, John E.; Wang, Jia-Sheng; Naeher, Luke P.

    2013-01-01

    Nearly half of the world’s population is exposed to household air pollution (HAP) due to long hours spent in close proximity to unvented cooking fires. The effect of woodsmoke exposure on oxidative stress was examined by investigating the association between woodsmoke exposure and biomarkers of DNA oxidation (8-hydroxy-2′-deoxyguanosine [8-OHdG]) and lipid peroxidation (8-isoprostane) among control and intervention stove users. HAP exposure assessment was conducted within the framework of a community-randomized controlled trial of 51 communities in San Marcos Province, Cajamarca Region, Peru. The first morning urine voids after 48hr HAP exposure assessment from a subset of 45 control and 39 intervention stove users were analyzed for 8-OHdG and 8-isoprostane. General linear models and correlation analyses were performed. Urinary oxidative stress biomarkers ranged from 11.2 to 2270.0 μg/g creatinine (median: 132.6 μg/g creatinine) for 8-OHdG and from 0.1 to 4.5 μg/g creatinine (median: 0.8 μg/g creatinine) for 8-isoprostane among all study subjects (n=84). After controlling for the effects of traffic in the community and eating food exposed to fire among all subjects, cooking time was weakly, but positively associated with urinary 8-OHdG (r=0.29, p=0.01, n=80). Subjects’ real-time personal CO exposures were negatively associated with 8-OHdG, particularly the maximum 30-second CO exposure during the sampling period (r=−0.32, p=0.001, n=73). 48hr time integrated personal PM2.5 was negatively, but marginally associated with urinary 8-isoprostane (r=−0.21, p=0.09, n=69) after controlling for the effect of distance of homes to the road. Urinary 8-isoprostane levels reported in the available literature are comparable to results found in the current study. However there were relatively high levels of urinary 8-OHdG compared to data in the available literature for 8-OHdG excretion. Results suggest a sustained systemic oxidative stress among these Peruvian women chronically exposed to wood smoke. PMID:24041735

  18. [The role of the class A scavenger receptors, SR-A and MARCO, in the immune system. Part 1. The structure of receptors, their ligand binding repertoires and ability to initiate intracellular signaling].

    PubMed

    Józefowski, Szczepan

    2012-01-01

    Recognition of pathogens by innate immune cells is mediated by pattern recognition receptors (PRR), which include scavenger receptors (SR). The class A SR, SR-A/CD204 and MARCO, are characterized by the presence of collagenous and SR cysteine-rich domains in their extracellular portions. Both receptors are expressed mainly on macrophages and dendritic cells. Thanks to their ability to bind to a wide range of polyanionic ligands, the class A SR may participate in numerous functions of these cells, such as endocytosis, and adhesion to extracellular matrix and to other cells. Among SR-A ligands are oxidized lipoproteins and β-amyloid fibrils, which link SR-A to the pathogenesis of arteriosclerosis and Alzheimer's disease. Despite the demonstration of class A SR involvement in so many processes, the lack of selective ligands precluded reaching definite conclusions concerning their signaling abilities. Using specific receptor ligation with antibodies, we showed that SR-A and MARCO trigger intracellular signaling, modulating pro-inflammatory and microbicidal activities of macrophages. Surprisingly, despite similarities in structure and ligand binding repertoires, SR-A and MARCO exert opposite effects on interleukin-12 (IL-12) production in macrophages. SR-A ligation also stimulated H₂O₂ and IL-10 production, but had no effect on the release of several other cytokines. These limited effects of specific SR-A ligation contrast with generalized enhancement of immune responses observed in SR-A-deficient mice. Recent studies have revealed that many of these effects of SR-A deficiency may be caused by compensatory changes in the expression of other receptors and/or disinhibition of signal transduction from receptors belonging to the Toll/IL-1R family, rather than by the loss of the receptor function of SR-A. PMID:22470185

  19. Los plaguicidas y la contaminacion del medio ambiente Venezolano

    USGS Publications Warehouse

    Stickel, L.F.; Stickel, W.H.

    1972-01-01

    RESUMEN DE RECOMENDACIONES Recomendaciones para el Programa de Investigacion: 1. Establecer un sistema de muestreo biologico para detectar los niveles tendencias de los productos quimicos toxicos en un peque?o numero de si tios representativos. 2. Mantener continua vigilancia de la contaminacion ambiental, mediante la seleccion acertadamente dirigida de las zonas afectadas y de las fuentes de contaminacion. 3. Realizar estudios acerca de las poblaciones de animales silvestres, y del exito de los procesos reproductivos de las especies o grupos clayes de animales que se consideran mas gravemente afectados. 4. Preparar recomendaciones para una accion gubernamental de proteccion al hombre, a la fauna silvestre y al medio ambiente. Recomendaciones para la Accion Administrativa: 1. Establecer limites a la tolerancia de los residuos de plaguicidas en los alimentos. Constituye una medida clave para disminuir la contaminacion ambiental. 2. Establecer normas de calidad del agua para las corrientes, represas, la gos y otros cuerpos. Es la segunda medida clave para reducir la contaminacion del ambiente 3. Exigir un tratamiento adecuado de los efluentes industriales, especialmente antes de que se construyan las nuevas plantas. 4. Exigir a los agricultores que en el uso de plaguicidas sigan los consejos tecnicos autorizados y negar a los vendedores el derecho a recomendar productos por su cuenta. 5. Tomar medidas para recoger y eliminar los recipientes y sobrantes de los plaguicidas.

  20. Seminario Tecnico Regional Sobre Alternativas de Educacion Basica de Adultos en el Marco de la REDALF del Proyecto Principal de Educacion en America Latina y el Caribe (Colonia Tovar, Venezuela, 29 de Septiembre al 3 de Octubre, 1986). Documento Final. (Regional Seminar on Alternatives for Basic Adult Education in the REDALF Project for Education in Latin America and the Caribbean (Colonia Tovar, Venezuela, September 29-October 3, 1986). Final Document.)

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific, and Cultural Organization, Santiago (Chile). Regional Office for Education in Latin America and the Caribbean.

    The final report of a conference concerning adult basic education de Adultos en el Marco de la REDALF del related to innovative projects in adult education in nine countries. A wide spectrum of issues related to adult basic education, curriculum, methodology, evaluation, and research are analyzed in the context of educational planning. Among the…

  1. 76 FR 72369 - Safety Zone; Marco Island Marriott Charity Fireworks Display, Gulf of Mexico, Marco Island, FL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-23

    ...: (202) 493-2251. (3) Mail: Docket Management Facility (M-30), U.S. Department of Transportation, West.... Wright, Program Manager, Docket Operations, telephone (202) 366- 9826. SUPPLEMENTARY INFORMATION: Public... received by the Coast Guard when it is received at the Docket Management Facility. We recommend that...

  2. VizieR Online Data Catalog: Binarity in planetary nebula central stars (De Marco+ 2013)

    NASA Astrophysics Data System (ADS)

    De Marco O.; Passy, J.-C.; Frew, D. J.; Moe, M.; Jacoby, G. H.

    2014-01-01

    The sample presented here consists of 30 central stars of PN which were selected solely based on their low PN surface brightness (radius of the PN is larger than ~25arcsec in most cases) as well as on the faint V magnitudes of their central stars. The observations were acquired during eight nights between 2007 October 30 and November 6 at the 2.1-m telescope at the Kitt Peak National Observatory. However, the data from nights 2 and 8 were not photometric. (5 data files).

  3. Marco Said I Look like Charcoal: A Puerto Rican's Exploration of Her Ethnic Identity

    ERIC Educational Resources Information Center

    Vargas, Yarma Velazquez

    2008-01-01

    When race is so self-evident that it becomes "unspoken," it becomes a text that can be arbitrarily read or not read at all. When race is thought of as shades or textures of color that paint the already loaded canvas of our ethnicities, it is the reader who has the power of interpretation, opening the possibility for multiple readings that will

  4. A passively controlled appendage deployment system for the San Marco D/L spacecraft

    NASA Technical Reports Server (NTRS)

    Lang, W. E.; Frisch, H. P.; Schwartz, D. A.

    1984-01-01

    The analytical simulation of deployment dynamics of these two axis concepts as well as the evolution of practical designs for the add on deployable inertia boom units is described. With the boom free to swing back in response to Coriolis forces as well as outwards in response to centrifugal forces, the kinematics of motion are complex but admit the possibility of absorbing deployment energy in frictional or other damping devices about the radial axis, where large amplitude motions can occur and where the design envelope allows more available volume. An acceptable range is defined for frictional damping for any given spin rate. Inadequate damping allows boom motions which strike the spacecraft; excessive damping causes the boom to swing out and latch with damaging violence. The acceptable range is a design parameter and must accommodate spin rate tolerance and also the tolerance and repeatability of the damping mechanisms.

  5. DOE Zero Energy Ready Home Case Study: KB Homes, San Marcos, California

    SciTech Connect

    none,

    2013-09-01

    Designed to produce as much energy as it uses, the ZeroHouse incorporates a PV system, R-15 fiberglass batts in walls, and slab-on-grade foundation. The builder ranked fifth in the nation on Builder Magazine’s 2012 Top 100 ranking of U.S. home builders based on number of housing starts, and won a 2013 Housing Innovation Award in the production builder category.

  6. Marco Said I Look like Charcoal: A Puerto Rican's Exploration of Her Ethnic Identity

    ERIC Educational Resources Information Center

    Vargas, Yarma Velazquez

    2008-01-01

    When race is so self-evident that it becomes "unspoken," it becomes a text that can be arbitrarily read or not read at all. When race is thought of as shades or textures of color that paint the already loaded canvas of our ethnicities, it is the reader who has the power of interpretation, opening the possibility for multiple readings that will…

  7. VizieR Online Data Catalog: uvby photometry in NGC 7419 (Marco+, 2013)

    NASA Astrophysics Data System (ADS)

    Marco, A.; Negueruela, I.

    2013-02-01

    The open cluster NGC 7419 is known to contain five red supergiants and a very high number of Be stars. However, there are conflicting reports about its age and distance that prevent a useful comparison with other clusters. We intend to obtain more accurate parameters for NGC 7419, using techniques different from those of previous authors, so that it may be used as a calibrator for more obscured clusters. We obtained Stroemgren photometry of the open cluster NGC 7419, as well as classification spectroscopy of ~20 stars in the area. We then applied standard analysis and classification techniques. (3 data files).

  8. VizieR Online Data Catalog: Photometry of VdBH 222 stars and field stars (Marco+, 2014)

    NASA Astrophysics Data System (ADS)

    Marco, A.; Negueruela, I.; Gonzalez-Fernandez, C.; Maiz Apellaniz, J.; Dorda, R.; Clark, J. S.

    2014-05-01

    We obtained UBVR photometry of VdBH 222 using the ESO Faint Object Spectrograph and Camera (EFOSC2) on the NTT on the night of 24 June 2012. The instrument was equipped with CCD#40, which is a Loral/Lesser, thinned, AR-coated, UV-flooded, and MPP chip that is controlled by ESO-FIERA. It covers a field of view of and 4.1'x4.1' and has a pixel scale of 0.12". The JHK images were obtained using the Son OF Isaac (SOFI) near-IR spectrograph and camera on the NTT on 13 July 2008, equipped with a CCD providing a pixel scale of 0.288arcsec and an field of view of 4.92x4.95' (4 data files).

  9. Pathfinder Lander Rover Recharge System, and MARCO POLO Controls and ACME Regolith Feed System Controls and Integration

    NASA Technical Reports Server (NTRS)

    Tran, Sarah Diem

    2015-01-01

    This project stems from the Exploration, Research, and Technology Directorate (UB) Projects Division, and one of their main initiatives is the "Journey to Mars". Landing on the surface of Mars which is millions of miles away is an incredibly large challenge. The terrain is covered in boulders, deep canyons, volcanic mountains, and spotted with sand dunes. The robotic lander is a kind of spacecraft with multiple purposes. One purpose is to be the protective shell for the Martian rover and absorb the impact from the landing forces; another purpose is to be a place where the rovers can come back to, actively communicate with, and recharge their batteries from. Rovers have been instrumental to the Journey to Mars initiative. They have been performing key research on the terrain of the red planet, trying to unlock the mysteries of the land for over a decade. The rovers that will need charging will not all have the same kind of internal battery either. RASSOR batteries may differ from the PbAC batteries inside Red Rover's chassis. NASA has invested heavily in the exploration of the surface of Mars. A driving force behind further exploration is the need for a more efficient operation of Martian rovers. One way is to reduce the weight as much as possible to reduce power consumption given the same mission parameters. In order to reduce the mass of the rovers, power generation, communication, and sample analysis systems currently onboard Martian rovers can be moved to a stationary lander deck. Positioning these systems from the rover to the Lander deck allows a taskforce of smaller, lighter rovers to perform the same tasks currently performed by or planned for larger rovers. A major task in transferring these systems to a stationary lander deck is ensuring that power can be transferred to the rovers.

  10. APPLICATION OF COMPUTER-AIDED TOMOGRAPHY (CAT) AS A POTENTIAL INDICATOR OF MARINE MARCO BENTHIC ACTIVITY ALONG POLLUTION GRADIENTS

    EPA Science Inventory

    Sediment cores were imaged using a local hospital CAT scanner. These image data were transferred to a personal computer at our laboratory using specially developed software. Previously, we reported an inverse correlation (r2 = 0.98, P<0.01) between the average sediment x-ray atte...

  11. La Capacitacion de Docentes en el Marco de la Regionalizacion Educativa (In-Service Teacher Training within Educational Regional Planning).

    ERIC Educational Resources Information Center

    Valle, Victor M.

    A paper discusses inservice teacher training in the context of regionalized education, with reference to recent Latin American efforts to regionalize, decentralize, and de-concentrate educational systems in order to provide relavant and adequate regional educational systems and so make equal education possible. Basic concepts in regionalized…

  12. Recently discovered overthrusting northeast of Llano uplift along extension of San Marcos platform: new exploration frontier in central Texas

    SciTech Connect

    McMurdie, D.S.; Bryan, J.G.; Gibson, M.; King, T.; Sill, W.

    1986-05-01

    TJB Resources recently completed gravity, magnetotelluric, and seismic geophysical surveys in San Saba and Mills Counties north of the Llano uplift, west of the Ouachita Disturbed belt. Significant results show overthrusting has occurred 60-70 mi west of the Ouachita Disturbed belt. Earliest thrusting could have occurred in the Silurian-Devonian from south or southeast. Faulting reoccurs during Pennsylvanian Ouachita thrusting and again in the Late Cretaceous. The primitive Llano uplift buttressed the allochthonous rocks moving north and west. Magnetotelluric and gravity data indicate the Llano uplift is a separate and distinct isolated remnant or terrain, with numerous igneous intrusions reaching to great depths. Associated with this thrusting is a major tectonic northwest-southeast lineament located parallel to the termination of the Cretaceous rocks, outcropping on the western edge of Mills and Lampasas Counties. This lineament is documented by east-west seismic lines displaying a 0.3-sec displacement and farther southwest a 1.1-sec displacement. Paleozoic fossils were found near the surface trace of the northwest-southwest lineament as observed on the east-west seismic line. This area was previously mapped as Cretaceous. Surface inspection found Paleozoic rocks containing crinoids, spirifers, and rugose corals, with beds dipping to 45/sup 0/, contrasted with the N2/sup 0/ regional dip surrounding the lineament area. Well-log correlations from Marble Falls to Ellenberger range from 350 to 600 ft from east to west near the Llano uplift. The 60 to 70-mi frontal edge of the thrusting provides potential hydrocarbon traps along a north to northeast trend from central Texas to Oklahoma.

  13. Final Evaluation Report of the San Marcos Consolidated Independent School District's Bilingual Education Program, 1975-1976.

    ERIC Educational Resources Information Center

    Harrison, Helene W.

    Comprised of 27 classrooms from grade levels 1-6, the program was primarily designed to provide bilingual education for pupils with limited English speaking ability. However, due to parental requests, almost 16% monolingual English-speakers were accepted into the program. Of the 717 pupils participating in the program 84.6% were Mexican American.…

  14. Final Evaluation Report of the San Marcos Consolidated Independent School District's Bilingual Education Program, 1974-1975.

    ERIC Educational Resources Information Center

    Harrison, Helene W.

    The program is primarily designed to provide bilingual education for pupils, in grades K-6, with limited English-speaking ability. Due to parental requests, approximately 16 percent monolingual English-speakers have been accepted into the program. Of the 529 children enrolled in the program, 89 percent have Spanish surnames. Objectives for the…

  15. 1989 IEEE Annual Conference on Nuclear and Space Radiation Effects, 26th, Marco Island, FL, July 25-29, 1989, Proceedings. Part 1

    NASA Technical Reports Server (NTRS)

    Ochoa, Agustin, Jr. (editor)

    1989-01-01

    Various papers on nuclear science are presented. The general topics addressed include: basic mechanics of radiation effects, dosimetry and energy-dependent effects, hardness assurance and testing techniques, spacecraft charging and space radiation effects, EMP/SGEMP/IEMP phenomena, device radiation effects and hardening, radiation effects on isolation technologies, IC radiation effects and hardening, and single-event phenomena.

  16. Beyond the Reference Desk: A Study on the Effectiveness of Low-Cost Distance Library Services at California State University San Marcos

    ERIC Educational Resources Information Center

    Olivas, Antonia P.; Chan, Ian

    2013-01-01

    Many of our reference interactions are face-to-face at a desk or in our offices. Unfortunately, not all of our students are on campus. Whether a non-traditional student or a traditional undergraduate, more of our patrons are attending online classes or attending satellite campuses with no librarians on site. It's difficult to reach these…

  17. LOS COLEGIOS REGIONALES, OPORTUNIDADES DE ESTUDIO EN INSTITUCIONES DE NIVEL UNIVERSITARIO. (THE REGIONAL COLLEGES, OPPORTUNITIES FOR STUDY IN UNIVERSITY LEVEL INSTITUTIONS).

    ERIC Educational Resources Information Center

    BETANCOURT, ETHEL RIOS DE; AND OTHERS

    RECENT LEGISLATION IN PUERTO RICO HAS VALIDATED THE 2-YEAR REGIONAL COLLEGE CONCEPT, AND THE CHARACTER OF THE PROGRAM COMBINING LIBERAL ARTS TRANSFER CURRICULUMS AND VOCATIONAL EDUCATION HAS BEEN SET. TO IMPLEMENT THE PLANNING PHASES, THIS STUDY PREDICTS STUDENT ENROLLMENT BY REGION. TWO INDEXES ARE USED TO ESTIMATE STUDENT DEMAND--COLLEGE…

  18. La region en los procesos de planificacion Latinos Americanos. Estructura institucional y bases juridicas. (The Region in the Planning Processes in Latin America: Institutional Structures and Juridical Basis)

    ERIC Educational Resources Information Center

    Basaldua, Raul Oscar; Moreno, Oscar Alberto

    1971-01-01

    This paper is part of a larger research project on the decisional structure of regionalized countries, which the authors are conducting at the Instituto Torcuato Di Tella with the Arq. Jorge Hardoy. (Editor)

  19. 78 FR 14567 - Changes in Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-06

    ..., Marco Bald Eagle Drive, index.php/florida/ Island City Marco Island, FL collier/. Council, 50 Bald 34145. Eagle Drive, Marco Island, FL 34145. Collier City of Naples (12- The Honorable John Building...

  20. Archive of post-Hurricane Charley coastal oblique aerial photographs collected during U.S. Geological Survey field activity 04CCH01 from Marco Island to Fort DeSoto, Florida, August 15, 2004

    USGS Publications Warehouse

    Subino, Janice A.; Morgan, Karen L.M.; Krohn, M. Dennis; Miller, Gregory K.; Dadisman, Shawn V.; Forde, Arnell S.

    2012-01-01

    To view the survey maps and navigation files, and for more information about these items, see the Navigation page. Figure 1 displays the acquisition geometry. The tables provide detailed information about the assigned location, name, data, and time the photograph was taken along with links to the photo and corresponding 5-min contact sheet. Refer to table 1 and table 2 for details of the northern and southern county photographs, respectively.

  1. World bank's role in the electric power sector: Policies for effective institutional, regulatory, and financial reform. World Bank policy paper. Funcion del banco mundial en el sector de la electricidad: politicas para efectuar una reforma institucional, regulatoria y financiera eficaz

    SciTech Connect

    Not Available

    1993-01-01

    The paper outlines the World Bank's new policies for the energy sector. It recommends several new policies to improve the performance of the electric power sector in developing countries. Bank loans for electric power will go first to countries clearly committed to improving the performance of their power sectors. The Bank will also discourage subsidies on energy prices and will encourage private investment in utilities. And it will provide financing to help the least developed countries import power where local generation is not practical.

  2. Opportunities at Independent Colleges and Universities in New York State through the Higher Education Opportunity Program = Las Oportunidades en las Instituciones Independendientes de Nivel Universitario en el Estado de Nueva York a traves de los Programas de Oportunidades Educativas Universitarias.

    ERIC Educational Resources Information Center

    New York State Education Dept., Albany. Bureau of Higher Education Opportunity Programs.

    A guide to the opportunities at private colleges and universities in New York State through the Higher Education Opportunity Program (HEOP) is presented. The HEOP is designed to meet the special needs of students from disadvantaged backgrounds through screening, testing, counseling, tutoring, teaching, and financial assistance. Generally, students…

  3. Un Marco Abierto: Un Manual de Matematicas y Ciencas Utilizando Inteligencias Multiples Disenado para Estudiantes Bilingues de Educacion General y Especial (An Open Framework: A Math and Science Manual Utilizing Multiple Intelligences Designed for Bilingual Students in General and Special Education).

    ERIC Educational Resources Information Center

    New York City Board of Education, Brooklyn, NY. Office of Bilingual Education.

    This manual incorporates a Multiple Intelligences perspective into its presentation of themes and lesson ideas for Spanish-English bilingual elementary school students in grades 4-8 and is designed for both gifted and special education uses. Each unit includes practice activities, semantic maps to illustrate and help organize ideas as well as…

  4. Lo que Piensan los Estudiantes y Profesores Sobre la Calidad de la Educacion Superior. Estudio Comparativo en 5 Instituciones de Educacion Superior--dos publicas y tres privadas--en Guadalajara, Jalisco, Mexico (What Students and Faculties Think about the Quality of Higher Education. Comparative Study of 5 Higher Education Institutions--Two Public and Three Private--in Guadalajara, Jalisco, Mexico).

    ERIC Educational Resources Information Center

    Yanez, Maria Lorena Hernandez

    This study, written in Spanish, compared attitudes of students (N=302) and faculty (N=28) at five institutions of higher education (two public and three private) in Guadalajara, Jalisco, Mexico. The study explored first, whether respondents believed there are significant quality differences between private and public universities and, second, what…

  5. Manual for ERLE (Energy-Related Laboratory Equipment). Instructions and information for institutions of higher learning concerning used energy-related laboratory equipment grants; Manual para ERLE [Equipo de Laboratorio Relacionado con la Energia]. Instrucciones e informacion para instituciones de educacion superior sobre subvenciones de equipo de laboratorio usado relacionado con la energia

    SciTech Connect

    Not Available

    1994-10-01

    This is a listing of energy related equipment available through the Energy-Related Laboratory Equipment Grant Program which grants used equipment to institutions of higher education for energy-related research. Information included is an overview of the program, how to apply for a grant of equipment, eligibility requirements, types of equipment available, and the costs for the institution.

  6. List of Participating Institutions: Associated Schools Project in Education for International Co-operation and Peace = Liste des establissements participants: Systeme des ecoles associees appliquant un programme d'education pour la cooperation internationale et la paix = Lista de Instituciones Participantes: Plan de Escuelas Asociadas en la Educacion para la Cooperacion Internacional y la Paz.

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific, and Cultural Organization, Paris (France).

    A list of participating institutions at the Associated Schools Project in Education for International Co-Operation and Peace, December 31, 1985 is presented. A total of 1,970 institutions in 94 countries participated, including 47 nursery schools, 556 primary schools, 1,123 secondary schools, and 248 teacher training institutions. Addresses of…

  7. Comment on «Tidal notches in the Mediterranean Sea: A comprehensive analysis» by Fabrizio Antonioli, Valeria Lo Presti, Alessio Rovere, Luigi Ferranti, Marco Anzidei, Stefano Furlani, Giuseppe Mastronuzzi, Paolo E. Orru, Giovanni Scicchitano, Gianmaria Sannino, Cecilia R. Spampinato, Rossella Pagliarulo, Giacomo Deiana, Eleonora de Sabata, Paolo Sansò, Matteo Vacchi and Antonio Vecchio. Quaternary Science Reviews 119 (2015) 66-84

    NASA Astrophysics Data System (ADS)

    Evelpidou, Niki; Pirazzoli, Paolo

    2016-01-01

    The paper of Antonioli et al. (2015) presents observations of 73 sites with erosion notches, which are called tidal notches, which in fact appear to be of various genetic origins, because a combination of several physical chemical and biological processes of formation is considered including, in addition to intertidal bioerosion, also carbonate rock solution, wetting and drying and wave abrasion that would produce different types of notches. Among the erosion notches, some «roof notches», in which the notch lacks a floor, are distinguished. For these isolated roofs, we would tend to ascribe erosion to dissolution by a freshwater spring undercutting a limestone cliff at sea level. Accompanying a rise in sea level, dissolution by freshwater will tend to continuously displace the roof of the notch upwards, while the base of the notch, dissolved, will tend to be missing. For such isolated roof of a solution notch, protruding above the waterline, the term «visor» has been proposed by Evelpidou et al. (2011).

  8. NCI Relapse/Transplant Meeting 2012

    Cancer.gov

    Co-Chairs include:  Name Institute email Avigan, David Beth Israel Deaconess Medical Center davigan@bidmc.harvard.edu Cairo, Mitchell New York Medical College Mitchell_Cairo@NYMC.EDU De Lima, Marcos Case Western Reserve University Marcos.delima@uhhospital

  9. Two Sides of the Same Coin: Reaching Nontraditional Students

    ERIC Educational Resources Information Center

    Berg, Steven L.

    2005-01-01

    This paper presents interviews with Barbara Bonham, a Senior Researcher at the National Center for Developmental Education and a member of the faculty at the Kellogg Institute, Appalachian State University in Boone, North Carolina and Melanie Chu, the Outreach Librarian at Cal State San Marcos in San Marcos, California. In these interviews they…

  10. NCI Relapse/Transplant Meeting 2012

    Cancer.gov

    Biology Protocol Development Team Co-Chairs: John Dipersio, Mitchell Cairo Prevention Protocol Development Team Co-Chairs: Marcos De Lima, David Avigan Treatment Protocol Development Team Co-Chairs: Jeffrey Miller, David Porter

  11. NCI Relapse/Transplant Meeting 2012

    Cancer.gov

    Co-Chairs: David Avigan, Beth Israel Deaconess Medical Center Marcos De Lima, Case Western Reserve Members Michael Bishop, University of Chicago Nancy Hardy, National Cancer Institute Nicolaus Kröger, University of Hamburg Jeffrey Molldrem, MD Anderson Ca

  12. Stress Studies at Kennedy Space Center: a Backward and Forward Look

    NASA Technical Reports Server (NTRS)

    Decker, A. I.

    1971-01-01

    Possible relationships between occupational and other stresses on ischemic heart disease are explored. Three procedures were used: (1) double master 2-step test, (2) dynamic ECG technique using avionics equipment, and (3) submaximal stress testing with Marco bicycle ergometer.

  13. AAHM 2012: Systems Engineer Leading the Way - Duration: 2 minutes, 19 seconds.

    NASA Video Gallery

    Marco Midon, who is visually impaired, is highlighted for NASA's Black History Month. He is the Lead Systems Engineer who oversees the design and implementation of NASA ground stations in the area ...

  14. Capacitación de la fuerza laboral

    Cancer.gov

    El NCI es una organización gubernamental que capacita a la próxima generación de investigadores del cáncer en universidades e instituciones de todo el país y proporciona financiación para investigación científica.

  15. Promoting Tenth Graders' Reading Comprehension of Academic Texts in the English Class (Promoción de la comprensión de lectura de textos académicos de estudiantes de grado décimo en la clase de inglés)

    ERIC Educational Resources Information Center

    Quiroga Carrillo, Claudia

    2010-01-01

    This article reports on an action research project conducted in a public school in Bogotá, Colombia, with tenth grade students. We decided to develop it because of the students' needs as well as the em phasis of the PEI (Proyecto Educativo Institucional = School Institutional Project), which is based on the requisite of improving reading…

  16. Discovering New Dimensions in an Old Task: Higher-Ed Bilingual Professors Learn to Use Lesson Planning for Students' Educational Success

    ERIC Educational Resources Information Center

    Morales Henao, Enith Viviana; Peña Piragua, Angélica Paola

    2008-01-01

    Professors at the "Institucion Universitaria Colombo Americana" (UNICA) have aimed to deliver lessons for second language learners which integrate content and language, resulting in an "integrated lesson" design. The Center for Applied Linguistics (Washington, DC) recommends the Sheltered Instruction Observation Protocol (SIOP)…

  17. Achieving Conservation Science that Bridges the Knowledge–Action Boundary

    PubMed Central

    Cook, Carly N; Mascia, Michael B; Schwartz, Mark W; Possingham, Hugh P; Fuller, Richard A

    2013-01-01

    There are many barriers to using science to inform conservation policy and practice. Conservation scientists wishing to produce management-relevant science must balance this goal with the imperative of demonstrating novelty and rigor in their science. Decision makers seeking to make evidence-based decisions must balance a desire for knowledge with the need to act despite uncertainty. Generating science that will effectively inform management decisions requires that the production of information (the components of knowledge) be salient (relevant and timely), credible (authoritative, believable, and trusted), and legitimate (developed via a process that considers the values and perspectives of all relevant actors) in the eyes of both researchers and decision makers. We perceive 3 key challenges for those hoping to generate conservation science that achieves all 3 of these information characteristics. First, scientific and management audiences can have contrasting perceptions about the salience of research. Second, the pursuit of scientific credibility can come at the cost of salience and legitimacy in the eyes of decision makers, and, third, different actors can have conflicting views about what constitutes legitimate information. We highlight 4 institutional frameworks that can facilitate science that will inform management: boundary organizations (environmental organizations that span the boundary between science and management), research scientists embedded in resource management agencies, formal links between decision makers and scientists at research-focused institutions, and training programs for conservation professionals. Although these are not the only approaches to generating boundary-spanning science, nor are they mutually exclusive, they provide mechanisms for promoting communication, translation, and mediation across the knowledge–action boundary. We believe that despite the challenges, conservation science should strive to be a boundary science, which both advances scientific understanding and contributes to decision making. Logrando que la Ciencia de la Conservación Trasponga la Frontera Conocimiento-Acción Resumen Hay muchas barreras para utilizar ciencia para informar a la política y práctica de la conservación. Los científicos de la conservación que desean producir ciencia relevante para el manejo deben equilibrar esta meta con el imperativo de demostrar novedad y rigor en su ciencia. Los tomadores de decisiones que buscan que sus decisiones se basen en evidencias deben equilibrar el deseo de conocimientos con la necesidad de actuar a pesar de la incertidumbre. La generación de ciencia que informe efectivamente a las decisiones de manejo requiere que la producción de información (los componentes del conocimiento) sea sobresaliente (relevante y oportuna), creíble (autoritativa, verosímil y confiable) y legítima (desarrollada mediante un proceso que considera los valores y perspectivas de todos los actores relevantes) a la vista tanto de investigadores como de tomadores de decisiones. Percibimos tres retos clave para quienes desean generar ciencia de la conservación que logre estas tres características de la información. Primero, las audiencias científicas y de manejo pueden tener percepciones contrastantes sobre la relevancia de la investigación. Segundo, la credibilidad se puede lograr a costa de la relevancia y legitimidad a la vista de los tomadores de decisiones y tercero, los diferentes actores pueden tener percepciones conflictivas sobre los que constituye información legítima. Resaltamos cuatro marcos institucionales que pueden facilitar que la ciencia informe al manejo: organizaciones de frontera (organizaciones ambientales que trasponen la frontera entre la ciencia y el manejo), investigadores científicos insertados en agencias de manejo de recursos, vínculos formales entre tomadores de decisiones y científicos en instituciones enfocadas a la investigación, y programas de capacitación para profesionales de la conservación. Aunque estos no son los únicos métodos para generar ciencia que traspone fronteras, ni son mutuamente excluyentes, proporcionan mecanismos que promueven la comunicación, traslación y mediación para trasponer la frontera conocimiento-acción. Consideramos que no obstante los retos, la ciencia de la conservación debería pugnar por ser una ciencia de frontera, que incrementa el entendimiento científico y contribuye a la toma de decisiones. PMID:23574343

  18. The Oral Histories of Six African American Males in Their Ecology of Advanced Placement Biology

    ERIC Educational Resources Information Center

    Halasa, Katrina Bassam

    2012-01-01

    The major purpose of this qualitative study was to examine the past in order to understand the complex phenomenon of students engaging in science (Newman, Ridenour, Newman, & DeMarco, 2003) specifically through the oral histories of six self-identified African American males enrolled in a high school Advanced Placement Biology class and the

  19. Access to Vocational Guidance for People at Risk of Social Exclusion.

    ERIC Educational Resources Information Center

    Clayton, Pamela M., Ed.; Fojcik, Vavrinec; Greco, Silvana; Hulkko, Johanna; Kelly, Eimer; Kostka, Miroslav; McGill, Paul; Machackova, D.; Maiello, Marco; Makela, Eija; Sinorova, Lenka; Troska, Robert; Ward, Mary

    This document contains 7 papers that evolved from 44 case studies of access to vocational guidance for people at risk of social exclusion in 5 European countries. The following papers are included: "Introduction" (Pamela Clayton); "Access to Vocational Guidance in Italy" (Silvana Greco, Marco Maiello); "Access to Vocational Guidance in Ireland"…

  20. NCI Relapse Workshop November 2009

    Cancer.gov

    Committee members Name Institue email Pavletic, Steve (Co-Chair) NCI pavletis@mail.nih.gov Weisdorf, Daniel (Co-Chair) University of Minnesota weisd001@umn.edu De Lima, Marcos MD Anderson Cancer Center mdelima@mdanderson.org Foran, James University of Ala

  1. Interactive Technology Brings Algebra to All.

    ERIC Educational Resources Information Center

    Kennedy, Paul A.; Chavkin, Nancy Feyl

    1993-01-01

    Partnership for Access to Higher Mathematics uses fiber-optic technology in a partnership program among Southwest Texas State University, the San Marcos School District, the telephone company, and the community to significantly improve the mathematical skills of at-risk students. (MLF)

  2. Gas Hydrates Research Project in Japan

    Scientists from AIST, JOGMEC, Georgia Tech, and the USGS prepare to analyze pressure cores as part of a multi-year gas hydrates research project in Japan. In this photo is Marco Terzariol (Georgia Tech) is preparing a Direct Shear Cell for testing a core section from the manipulator (background), st...

  3. Another Way of Knowing: Visualizing the Ancient Silk Routes

    ERIC Educational Resources Information Center

    Bisland, Beverly Milner

    2010-01-01

    One way that people learn, remember and communicate is visually. We combine past experiences with new visual information to construct meaning. In this study, elementary teachers introduced their students to the peoples and places of the ancient silk routes using illustrations from two children's picture books, "Marco Polo," written by Gian Paolo…

  4. Constructing Knowledge with Silk Road Visuals

    ERIC Educational Resources Information Center

    Bisland, Beverly Milner

    2008-01-01

    In this study a group of elementary teachers use illustrations, rather than written text, to introduce their students to the peoples and places of the ancient silk routes. The illustrations are from two picture books; "Marco Polo," written by Gian Paolo Cesaerani and illustrated by Piero Ventura (1977), and "We're Riding on a Caravan: An Adventure…

  5. An Innovative Interdisciplinary Approach to Providing Internships for College Seniors

    ERIC Educational Resources Information Center

    Fuller, Kathy

    2015-01-01

    The undergraduate Business and Human Development (HD) Departments at California State University San Marcos (CSUSM), are collaborating in an innovative interdisciplinary approach to supporting internships with local businesses in order to provide college seniors with experiences in the area of career development known as the "Senior…

  6. Crisis in the Philippines: A Threat to U.S. Interests.

    ERIC Educational Resources Information Center

    Gregor, A. James

    The special relationship between the United States and the Philippines is chronicled, and the potential threats to that relationship are exposed and evaluated. Special attention is paid to imposition of martial law by Marcos from 1972-1981. The human rights of the Filipino people during martial law, development programs implemented by Marcos…

  7. 33 CFR 80.748 - Cape Romano, FL to Sanibel Island, FL.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Cape Romano, FL to Sanibel Island... Sanibel Island, FL. (a) A line drawn across Big Marco Pass parallel to the general trend of the seaward, highwater shoreline. (b) A line drawn from the northwesternmost extremity of Coconut Island 000°T...

  8. 33 CFR 80.748 - Cape Romano, FL to Sanibel Island, FL.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Sanibel Island, FL. (a) A line drawn across Big Marco Pass parallel to the general trend of the seaward... drawn across the seaward extremity of Doctors Pass Jetties. (f) Lines drawn across Wiggins, Big Hickory, New, and Big Carlos Passes parallel to the general trend of the seaward highwater shoreland. (g)...

  9. 33 CFR 80.748 - Cape Romano, FL to Sanibel Island, FL.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Sanibel Island, FL. (a) A line drawn across Big Marco Pass parallel to the general trend of the seaward... drawn across the seaward extremity of Doctors Pass Jetties. (f) Lines drawn across Wiggins, Big Hickory, New, and Big Carlos Passes parallel to the general trend of the seaward highwater shoreland. (g)...

  10. Bilingualism and Bilingual Education in a Complex Context

    ERIC Educational Resources Information Center

    Herrera, Lazaro Moreno; Wedin, Asa

    2010-01-01

    This article is based on results from a baseline study for an intended intervention project in bilingual-intercultural education in the Municipality of San Miguel Ixtahuacan, in the Department of San Marcos, Guatemala. To a great extent the article deals with issues of bilingual education from the perspective of social justice. It analyses the…

  11. Filipinos in America: Target Constituency for the "New Society".

    ERIC Educational Resources Information Center

    Richter, Linda

    The increasing number of Filipino immigrants to America has coincided with the martial law era in the Philippines. Consequently, this exodus has become a significant political issue for the government of Ferdinand Marcos. Since the Filipino government wishes to retain positive influence and goodwill with those who choose to settle elsewhere, it…

  12. Coping with Classroom Homophobia

    ERIC Educational Resources Information Center

    Brito, Marcos "Qboy"

    2007-01-01

    In this article, a version of which first appeared in the February 2007 number of Gay Times, gay rapper Marcos Brito describes his experiences of dealing with a general climate of homophobia at his secondary school in Essex. He argues that positive affirmations of lesbian, gay and bisexual people should be promoted as part of the school curriculum.

  13. Criterion-Referenced Exit Examinations: An Institution's Internal Process for Psychometric Analysis

    ERIC Educational Resources Information Center

    Lieneck, Cristian; Morrison, Eileen; Price, Larry

    2013-01-01

    The Texas State University-San Marcos undergraduate healthcare administration program requires all bachelors of health administration (BHA) students to pass a comprehensive examination to demonstrate their knowledge of specific core competencies. This also demonstrates completion of their didactic coursework in order to enter a practical…

  14. Panel fabrication utilizing GaAs solar cells

    NASA Technical Reports Server (NTRS)

    Mardesich, N.

    1984-01-01

    The development of the GaAs solar cells for space applications is described. The activities in the fabrication of GaAs solar panels are outlined. Panels were fabricated while introducing improved quality control, soldering laydown and testing procedures. These panels include LIPS II, San Marco Satellite, and a low concentration panel for Rockwells' evaluation. The panels and their present status are discussed.

  15. Doctoral Programs in Developmental Education: Interview with Three Leaders

    ERIC Educational Resources Information Center

    Kincaid, Marla

    2013-01-01

    Marla Kincaid (Adjunct Instructor, Austin Community College M.A., Developmental Education Department of Curriculum and Instruction Texas State University-San Marcos) interviewed the following leaders in the field of Developmental Education: (1) Dr. Olatunde Ogunyemi, Professor in the Department of Educational Leadership at Grambling State…

  16. 77 FR 31376 - Buy American Exceptions Under the American Recovery and Reinvestment Act of 2009

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-25

    ... published on April 23, 2009 (74 FR 18449), this notice advises the public that, on May 3, 2012, upon request... determined applicable for work using Capital Fund Recovery Formula and Competition (CFRFC) grant funds... installation of microwave ovens for the Marcos de Niza project. FOR FURTHER INFORMATION CONTACT: Donald J....

  17. Aula Verde: Art as Experience in Community-Based Environmental Education

    ERIC Educational Resources Information Center

    Abarca, Marco A.

    2010-01-01

    After winning a class-action lawsuit against unconstitutional prison conditions in Puerto Rico, Marco Abarca managed to direct part of the fine monies accumulated throughout years of litigation toward an investment that would improve the living conditions in one of the largest and poorest housing projects in Puerto Rico. With the participation of

  18. Molecular Targets Laboratory

    Cancer.gov

              Edmund Price Ju Hee Lim Oyebola Oladeinde Marcos da Cunha     Johns Hopkins Korea   Universidade Estadual de Campinas (UNCAMP) Brazil             Ana Sofia De Castro Valdeira Alejandro Rodriguez         Portugal Spain                            

  19. Academic Travel: Modes and Directions

    ERIC Educational Resources Information Center

    Barnett, Ronald; Phipps, Alison

    2005-01-01

    The Great Khan's atlas contains also the maps of the promised lands visited in thought but not yet discovered or founded: New Atlantis, Utopia, the City of the Sun, Oceana, Tamoe, New Harmony, New Lanark, Icaria. Kublai asked Marco: "You, who go about exploring and who see signs, can you tell me towards which of these futures the favouring winds…

  20. Great Explorers to the East.

    ERIC Educational Resources Information Center

    Baker, Rosalie F., Ed.; Baker, Charles F. III, Ed.

    1990-01-01

    This issue of "Calliope," a world history magazine for young people is devoted to "Great Explorers of the East" and features articles on famous explorers of the eastern hemisphere. The following articles are included: "Ancient Egyptian Mariners"; "Alexander: The Great Reconciler"; "Marco Polo: Describing the World"; "By Water to India";…

  1. Computer Literacy.

    ERIC Educational Resources Information Center

    San Marcos Unified School District, CA.

    THE FOLLOWING IS THE FULL TEXT OF THIS DOCUMENT: After viewing many computer-literacy programs, we believe San Marcos Junior High School has developed a unique program which will truly develop computer literacy. Our hope is to give all students a comprehensive look at computers as they go through their two years here. They will not only learn the…

  2. Academic Travel: Modes and Directions

    ERIC Educational Resources Information Center

    Barnett, Ronald; Phipps, Alison

    2005-01-01

    The Great Khan's atlas contains also the maps of the promised lands visited in thought but not yet discovered or founded: New Atlantis, Utopia, the City of the Sun, Oceana, Tamoe, New Harmony, New Lanark, Icaria. Kublai asked Marco: "You, who go about exploring and who see signs, can you tell me towards which of these futures the favouring winds

  3. Theory to Practice: Developmental Mathematics Program--A Model for Change

    ERIC Educational Resources Information Center

    Vasquez Mireles, Selina

    2010-01-01

    The Developmental Mathematics Program (DMP) at Texas State University-San Marcos in central Texas has undergone systemic, significant changes over the past ten years. These changes primarily resulted from the alignment to the American Mathematical Association of Two-Year Colleges' (AMATYC) Crossroads in Mathematics: Standards for Introductory…

  4. David Hurst Thomas and the Historical Archaeology of the Spanish Borderlands.

    ERIC Educational Resources Information Center

    Snead, James E.

    2000-01-01

    Discusses David Hurst Thomas' archaeological work on the Spanish borderlands, which integrates field archaeology and documentary history. Focuses on locating and studying the Santa Catalina de Guale. Addresses his project on the Pueblo San Marcos that will further test his ideas about the Spanish mission period. (CMK)

  5. The College & Financial Aid Guide for: AB540 Undocumented Immigrant Students

    ERIC Educational Resources Information Center

    Oliverez, Paz M., Ed.; Chavez, Maria Lucia, Ed.; Soriano, Mayra, Ed.; Tierney, William G., Ed.

    2006-01-01

    Since the passage of California Assembly Bill 540 in 2001, authored by the late Assemblyman, Marco Antonio Firebaugh, more than 5,000 undocumented students in California have had improved financial access to higher education. AB 540 has become a pinnacle in the lives of students, who because of their immigration status, have historically been…

  6. Computer Literacy.

    ERIC Educational Resources Information Center

    San Marcos Unified School District, CA.

    THE FOLLOWING IS THE FULL TEXT OF THIS DOCUMENT: After viewing many computer-literacy programs, we believe San Marcos Junior High School has developed a unique program which will truly develop computer literacy. Our hope is to give all students a comprehensive look at computers as they go through their two years here. They will not only learn the

  7. Motivate!

    ERIC Educational Resources Information Center

    Villano, Matt

    2008-01-01

    Mary Jo Garcia Biggs never really considered herself much of a technophile. Sure, the assistant professor at Texas State University-San Marcos knew her way around a web page, but for years, she was painfully aware of all of the technologies she didn't know much about. More times than not, the limitations of her knowledge frustrated the heck out of…

  8. Middle and upper atmosphere results; Proceedings of the Topical Meeting of the Interdisciplinary Scientific Commission C (Meetings C2 and C3) of the COSPAR 28th Plenary Meeting, The Hague, Netherlands, June 25-July 6, 1990

    NASA Technical Reports Server (NTRS)

    Keating, G. M. (Editor); Herrero, F. A. (Editor); Chakrabarti, S. (Editor); Gray, L. J. (Editor)

    1993-01-01

    Papers are first presented on atmospheric trace species, with particular attention given to stratospheric trace species and possible improvements to reference atmospheres. The equatorial thermosphere and aeronomy are considered with reference to models and San Marco satellite/ground-based observations. Papers on the coupling of dynamic, radiative, and chemical processes in the middle atmosphere are also presented.

  9. 76 FR 49541 - Endangered and Threatened Wildlife and Plants; Emergency Listing of the Miami Blue Butterfly as...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-10

    ... islands that previously supported the Miami blue, including Marco and Chokoloskee Islands, have... Listing as Endangered or Threatened Species (49 FR 21664), which included the Miami blue butterfly... proposal. In a January 6, 1989, Animal Notice of Review (54 FR 572), the Miami blue butterfly continued...

  10. International ties. [international cooperation in the space sciences

    NASA Technical Reports Server (NTRS)

    1980-01-01

    A historical overview of NASA's participation in international activities in space science is given. The Ariel, Alouette, Isis, and San Marco satellite programs are addressed along with sounding rocket and ground based projects. Relations and cooperation with the Soviet Union are also discussed.

  11. Bilingualism and Bilingual Education in a Complex Context

    ERIC Educational Resources Information Center

    Herrera, Lazaro Moreno; Wedin, Asa

    2010-01-01

    This article is based on results from a baseline study for an intended intervention project in bilingual-intercultural education in the Municipality of San Miguel Ixtahuacan, in the Department of San Marcos, Guatemala. To a great extent the article deals with issues of bilingual education from the perspective of social justice. It analyses the

  12. From Social Identity to Professional Identity: Issues of Language and Gender

    ERIC Educational Resources Information Center

    Velez-Rendon, Gloria

    2010-01-01

    This study draws from sociocultural theory to examine how biographical factors interplay with contextual factors to shape the professional identity of a Spanish language teacher candidate. Specifically, it explores the student teaching experience of Marcos, a 30-year-old language teacher candidate from South America. Analysis of the data reveals…

  13. Practical Ideas and Resources for Offering a Quality Group Program to Spanish-Speaking Families and Their Infants and Toddlers.

    ERIC Educational Resources Information Center

    Valdivia, Rebeca

    This conference presentation describes services to Spanish speaking families developed by the Hope Infant Family Support Program in San Marcos, California. It discusses the program's evolution from one-on-one translation, to a more bilingual program, to monolingual Spanish, and shares the pitfalls and the successful strategies encountered in…

  14. In Search of the Middle School Teacher: Navigating Research, Reality, and Mission

    ERIC Educational Resources Information Center

    Chen, Rong-Ji; Daniels, Erika; Chaplin, Mae S.; Ochanji, Moses; Stowell, Laurie P.; McDaniel, Janet E.

    2012-01-01

    The Middle Level Program at California State University San Marcos is the only middle level teacher credential program in the state of California. The program is based on a set of goals and philosophy of middle grades education, recognizing the developmental needs of young adolescents in Grades 5 through 9, and the socially equitable experience of…

  15. Ancient Media in Literature: Golden Printers and Golden Authors.

    ERIC Educational Resources Information Center

    Mooradian, Karlen

    Seal printing is explored as a literary topic in 28 works dating from the third millennium B.C. to A.D. 1613 (from Sumerian times through Shakespeare's). This ancient printing method is mentioned in the literature of the Egyptians, Greeks, Hebrews, and Arabians. It occurs in the works of Herodotus, Plutarch, and Marco Polo, as well as Chaucer and…

  16. The Oral Histories of Six African American Males in Their Ecology of Advanced Placement Biology

    ERIC Educational Resources Information Center

    Halasa, Katrina Bassam

    2012-01-01

    The major purpose of this qualitative study was to examine the past in order to understand the complex phenomenon of students engaging in science (Newman, Ridenour, Newman, & DeMarco, 2003) specifically through the oral histories of six self-identified African American males enrolled in a high school Advanced Placement Biology class and the…

  17. Commensal Bacteria Control Cancer Response to Therapy by Modulating the Tumor Microenvironment | Poster

    Cancer.gov

    Noriho Iida, Amiran Dzutsev, C. Andrew Stewart, Loretta Smith, Nicolas Bouladoux, Rebecca A. Weingarten, Daniel A. Molina, Rosalba Salcedo, Timothy Back, Sarah Cramer, Ren-Ming Dai, Hiu Kiu, Marco Cardone, Shruti Naik, Anil K. Patri, Ena Wang, Francesco M. Marincola, Karen M. Frank, Yasmine Belkaid, Giorgio Trinchieri, Romina S. Goldszmid Science 342(6161):967-970, 2013

  18. Early Childhood in the New China: Suzhou

    ERIC Educational Resources Information Center

    Kalinowski, Michael

    2010-01-01

    Suzhou is one hour to the West of Shanghai, and one of China's most interesting cities, famous for its silks, canals, and scholar gardens. According to a popular legend, Marco Polo is reputed to have said, "In heaven there is paradise, and on earth, Hangzhou and Suzhou." As the city rapidly expands, the issue of early childhood education is a…

  19. Small Steps, Big Changes: Eight Essential Practices for Transforming Schools through Mathematics

    ERIC Educational Resources Information Center

    Confer, Chris; Ramirez, Marco

    2012-01-01

    During the past two decades, Chris Confer and Marco Ramirez have worked to deepen and improve mathematics instruction at schools around the country. Wherever they go, they find the raw ingredients for success already present: "The potential for positive change lies within each school. Abundance is present in the form of capable children, teachers,…

  20. The Role of Macrophage Class A Scavenger Receptors in a Laser-Induced Murine Choroidal Neovascularization Model

    PubMed Central

    Jawad, Shayma; Liu, Baoying; Li, Zhiyu; Katamay, Robert; Campos, Mercedes; Wei, Lai; Sen, H. Nida; Ling, Diamond; Martinez Estrada, Fernando; Amaral, Juan; Chan, Chi-Chao; Fariss, Robert; Gordon, Siamon; Nussenblatt, Robert B.

    2013-01-01

    Purpose. Laser-induced choroidal neovascularization (CNV) is a widely used model to mimic many features of CNV resulting from wet AMD. Macrophages have been implicated in the pathogenesis of AMD. Class A scavenger receptors, scavenger receptor-A (SR-A) and macrophage receptor with collagenous domain (MARCO), are expressed on macrophages and are associated with macrophage function. The goal of this study is to examine the role of macrophage scavenger receptors in immune cell recruitment and the formation of CNV. Methods. Laser photocoagulation was performed in wild-type and knockout mice with deletion of SR-A (SR-A?/?), MARCO (MARCO?/?), or both SR-A and MARCO double knockout (DKO). Immune cell recruitment at different time points and CNV lesions at 14 days after laser treatment were evaluated through immunostaining and confocal microscopy. Microarray analysis was performed in eyes 1 day after laser injury. Results. Wild-type eyes showed higher chemokine/receptor expression compared with knockout eyes after laser injury. Scavenger receptor deficiency markedly impaired the recruitment of neutrophils and macrophages to CNV lesions at 1- and 3-days post laser injury, respectively. Significantly reduced CNV volumes were found in the eyes from scavenger receptor knockout mice compared with wild-type mice. Conclusions. The deficiency of scavenger receptors impairs the formation of CNV and immune cell recruitment. Our findings suggest a potential role for scavenger receptors in contributing to CNV formation and inflammation in AMD. PMID:23927892

  1. Corrigendum

    PubMed Central

    2016-01-01

    The TNF-?/NF-?B signaling pathway has a key role in methamphetamineinduced bloodbrain barrier dysfunction Vanessa Coelho-Santos, Ricardo A Leito, Filipa L Cardoso, Ins Palmela, Manuel Rito, Marcos Barbosa, Maria A Brito, Carlos A Fontes-Ribeiro and Ana P Silva Journal of Cerebral Blood Flow & Metabolism 2015; 35: 12601271. PMID:26814200

  2. School Subtracts Math Texts to Add E-Lessons, Tests

    ERIC Educational Resources Information Center

    Trotter, Andrew

    2007-01-01

    This article discusses how math teachers at San Marcos High School turned to an online curriculum and in-class assessments to increase student achievement. Setting aside their 7-year-old textbooks, teachers filled the void largely with an online math curriculum, called Agile Mind, that comes equipped with an array of assessment tools. The idea was…

  3. Criterion-Referenced Exit Examinations: An Institution's Internal Process for Psychometric Analysis

    ERIC Educational Resources Information Center

    Lieneck, Cristian; Morrison, Eileen; Price, Larry

    2013-01-01

    The Texas State University-San Marcos undergraduate healthcare administration program requires all bachelors of health administration (BHA) students to pass a comprehensive examination to demonstrate their knowledge of specific core competencies. This also demonstrates completion of their didactic coursework in order to enter a practical

  4. Gas Hydrates Research Project in Japan

    Photograph of the international team studying gas hydrates in Japan. Front row, kneeling: Jun Yoneda (AIST). Front row, standing, left to right: Yoshihiro Konno (AIST), Jiro Nagao (AIST), Marco Terzariol (Georgia Tech), William Winters (USGS), Junbong Jang (Georgia Tech), Kiyofumi Suzuki (JOGMEC), S...

  5. Gas Hydrates Research Project in Japan

    Scientists from AIST, JOGMEC, Georgia Tech, and the USGS prepare to analyze pressure cores as part of a multi-year gas hydrates research project in Japan. Standing, left to right: Jun Yoneda (AIST), Masato Kida (AIST), Marco Terzariol (Georgia Tech), Sheng Dai (Georgia Tech), Efthymios Papadopoulos ...

  6. Gas Hydrates Research Project in Japan

    Scientists from AIST, JOGMEC, Georgia Tech, and the USGS prepare to analyze pressure cores as part of a multi-year gas hydrates research project in Japan. Left to right: Emile Bergeron (USGS), Kiyofumi Suzuki (JOGMEC), Marco Terzariol (Georgia Tech), William Waite (USGS), and Carlos Santamarina (Geo...

  7. An REU Experience with Micro Assembly Workcell Research

    ERIC Educational Resources Information Center

    Stapleton, William; Asiabanpour, Bahram; Jimenez, Jesus; Um, Dugan

    2010-01-01

    Under an NSF REU center grant REU-0755355 entitled "Micro/Nano Assembly Workcell Via Micro Visual Sensing and Haptic Feedback", Texas A&M University-Corpus Christi and Texas State University-San Marcos collaboratively hosted two groups of 10 students from different backgrounds for 10 weeks each in Summer 2008 and 2009 respectively.…

  8. Anchor Test Type and Population Invariance: An Exploration across Subpopulations and Test Administrations

    ERIC Educational Resources Information Center

    Dorans, Neil J.; Liu, Jinghua; Hammond, Shelby

    2008-01-01

    This exploratory study was built on research spanning three decades. Petersen, Marco, and Stewart (1982) conducted a major empirical investigation of the efficacy of different equating methods. The studies reported in Dorans (1990) examined how different equating methods performed across samples selected in different ways. Recent population…

  9. Aula Verde: Art as Experience in Community-Based Environmental Education

    ERIC Educational Resources Information Center

    Abarca, Marco A.

    2010-01-01

    After winning a class-action lawsuit against unconstitutional prison conditions in Puerto Rico, Marco Abarca managed to direct part of the fine monies accumulated throughout years of litigation toward an investment that would improve the living conditions in one of the largest and poorest housing projects in Puerto Rico. With the participation of…

  10. Learning Languages: The Journal of the National Network for Early Language Learning, 2001-2002.

    ERIC Educational Resources Information Center

    Rosenbusch, Marcia H., Ed.

    2002-01-01

    These three journal issues contain the following articles: "Japanese at Mimosa Elementary School" (Azusa Uchihara); "A Successful Keypal Project Using Varied Technologies" (Jean L. Pacheco); "Promoting a Language-Proficient Society: What You Can Do" (Kathleen M. Marcos and Joy Kreeft Peyton); "Journal Reflections of a First-Year Teacher" (Sarah…

  11. FORMATION OF INTRACYTOPLASMIC MEMBRANE SYSTEM OF MYCOBACTERIA RELATED TO CELL DIVISION

    PubMed Central

    Imaeda, Tamotsu; Ogura, Mituo

    1963-01-01

    Imaeda, Tamotsu (Instituto Venezolano de Investigaciones Científicas, Caracas, Venezuela) and Mitua Ogura. Formation of intracytoplasmic membrane system of mycobacteria related to cell division. J. Bacteriol. 85:150–163. 1963.—Mycobacterium leprae, M. lepraemurium, and a Mycobacterium sp. were observed with an electron microscope. In these bacilli, the three-dimensional structure of the intracytoplasmic membrane system consists of tubular infoldings of the invaginated plasma membrane. The moderately dense substance, presumably representing the cell-wall precursor, is found in the membranous system, especially in the rapid growth phase of mycobacteria. This system always shows an intimate relationship with cell division. A low-density zone, probably corresponding to the low-density substance which coats the cell wall, appears in the connecting regions of the system and in the longitudinal portion of the cell wall. These zones extend centripetally, and the separation of the cell wall occurs after the two zones meet. Based on these results, we hypothesize that the intracytoplasmic membrane system may produce cell-wall material during cell division of mycobacteria. Images PMID:13956365

  12. [Promising networks, fruitful inquiry].

    PubMed

    Frenk, Silvestre

    2014-01-01

    This supplement of the Revista Médica del Instituto Mexicano del Seguro Social includes 10 original contributions, and also six current themes, all of them related to childhood obesity. It is the result of an institutional program that it has been identified as Redes de Investigación Institucional, and it has been promoted and developed by the Coordinación de Investigación of the Instituto Mexicano del Seguro Social. PMID:24866301

  13. Women in Physics in Perú

    NASA Astrophysics Data System (ADS)

    Loayza, María Luisa Cerón; Vásquez, Yezeña Huaypar; Cabrejos, Jorge Aurelio Bravo

    2009-04-01

    The numbers of women receiving undergraduate and master's degrees in physics from San Marcos National University and undergraduate physics degrees from San Luis Gonzaga National University in Perú are reported. The number of undergraduate degrees in physics has increased for women in San Marcos University, but not for women earning master's degrees. Why don't women complete their post-degree studies? Economics and gender stereotypes are factors that women in Perú have to fight each day. Perú does not have a good scholar program in science, so few students are interested in beginning their university careers in science. Improvements in science education are needed for our country to reach its potential.

  14. Investigation of the role of gravity waves in the generation of equatorial bubbles. Technical progress report, 1 May 1994-28 February 1995

    SciTech Connect

    Johnson, F.S.; Coley, W.R.

    1995-02-01

    The following areas of interest in this progress report are: (1) the continuation of software development in the examination of F-region gravity-wave power using in-situ data from the Atmosphere Explorer (AE-E); (2) the inquiry into the use of the San Marco data for the study of the initiation and growth of bubbles, particularly when the satellite passes through the early evening hours at relatively high altitudes, and the development of bubbles using not only the San Marco data but includes the use of airglow observations made in Hawaii; and (3) the promising development in the observation of distinct well formed waves at about 400 km altitude in the equatorial region. These waves look very much like waves seen over the polar cap that are attributed to internal gravity waves in the neutral atmosphere driving ionization up and down the magnetic field lines. These equatorial waves show no modulation of the total ion concentration.

  15. Investigation of the role of gravity waves in the generation of equatorial bubbles

    NASA Technical Reports Server (NTRS)

    Johnson, Francis S.; Coley, William R.

    1995-01-01

    The following areas of interest in this progress report are: (1) the continuation of software development in the examination of F-region gravity-wave power using in-situ data from the Atmosphere Explorer (AE-E); (2) the inquiry into the use of the San Marco data for the study of the initiation and growth of bubbles, particularly when the satellite passes through the early evening hours at relatively high altitudes, and the development of bubbles using not only the San Marco data but includes the use of airglow observations made in Hawaii; and (3) the promising development in the observation of distinct well formed waves at about 400 km altitude in the equatorial region. These waves look very much like waves seen over the polar cap that are attributed to internal gravity waves in the neutral atmosphere driving ionization up and down the magnetic field lines. These equatorial waves show no modulation of the total ion concentration.

  16. Aggradation in response to extreme flooding and watershed management

    NASA Astrophysics Data System (ADS)

    Engel, F. L.; Curran, J. C.

    2006-12-01

    In 1998, the San Marcos River, located along the Balcones Escarpment in Central Texas, experienced the largest flood in its recorded history. The San Marcos is a heavily managed watershed containing flood control dams, reaches of channelized flow, and a man made lake. This study examines changes to the fluvial system as a result of the combination of an extreme flow event and watershed management practices. The flood caused mass wasting and channel bed aggradation. Since the flood, watershed management practices and flood retention structures have reduced the ability of the flows to transport sediment through the channel. Results indicate that since flood control measures were implemented, only two flood events could have produced any significant transport of material in the study reach. The lasting effect has been an increase in the width to depth ratio in the downstream portion of the river and the creation of a large sediment bar in the upstream channel reach.

  17. The harmonic oscillator behind all aberrations

    SciTech Connect

    Wolf, Kurt Bernardo

    2010-12-23

    The group-theoretical structure of the harmonic oscillator appears in many guises. Originally developed by Marcos Moshinsky among several others for applications in nuclear physics, we point out here that the harmonic oscillator structure appears in aberrations of geometric optics, particularly in their classification by rank, symplectic spin and weight. And further, the finite harmonic oscillator appears again in the nonlinear transformations of finite Hamiltonian systems, when applied to the parallel processing of signals.

  18. Philippines.

    PubMed

    1986-08-01

    The Philippines is an archipelago of 7100 islands and islets, 11 of which compose about 95% of the total area and population. The majority of the Filipinos are descendants of Indonesians and Malays. Approximately 90% of the population are Christian with the majority of the remaining 10% being Moslems. In the 1960s, the annual population growth rate was roughly 3%, but it fell to 2.4% in the late 1970s and was still 2.4% in 1985. In 1970, President Marcos implemented an official family planning policy to reduce the high growth rate and thereby stimulate economic development. A population commission coordinates family planning efforts. Both the Spanish (1521-1898) and the United States (1898-1946) have ruled the Philippines with a brief occupation by the Japanese (1942-1945). The US assisted in the reconstruction of the economy following World War II and continues to maintain and operate military bases. Further, from 1946-1986, the Philippines has received $3.7 billion in economic and military assistance from the US. The government operated under a constitutional democracy from 1946-1972, but in 1972 President Marcos declared martial law. In 1981, martial law ended and Marcos called for a presidential election. After winning the election, he called for an amendment of the 1972 constitution making him, rather than the prime minister, the head of government. Even though martial law ended in 1981, the Marcos government retained its wide powers to arrest and detain anyone. In February 1986, popular support backed by a peaceful civilian-military uprising brought Corazon Aquino to the Presidency. In the mid 1980s a severe economic recession hit the Philippines with the real GNP growth rate ranging from -5.3%-0%. The Philippines have diplomatic relations with the south east Asian nations, many East Bloc nations, the US, China, Cuba, and the Soviet Union. PMID:12178014

  19. Cover Caption.

    PubMed

    2015-12-01

    December Online Cover: Geometric and temperature distribution models of broccoli florets, from "Heat Transfer during Blanching and Hydrocooling of Broccoli Florets" by Rosalina Iribe-Salazar, José Caro-Corrales, Óscar Hernández-Calderón, Jorge Zazueta-Niebla, Roberto Gutiérrez-Dorado, Marco Carrazco-Escalante, and Yessica Vázquez-López; p. E2774. PMID:26769103

  20. Corrigendum.

    PubMed

    2016-02-01

    The TNF-α/NF-κB signaling pathway has a key role in methamphetamine-induced blood-brain barrier dysfunctionVanessa Coelho-Santos, Ricardo A Leitão, Filipa L Cardoso, Inês Palmela, Manuel Rito, Marcos Barbosa, Maria A Brito, Carlos A Fontes-Ribeiro and Ana P SilvaJournal of Cerebral Blood Flow & Metabolism 2015; 35: 1260-1271. PMID:26814200

  1. Rocket borne solar eclipse experiment to measure the temperature structure of the solar corona via lyman-. cap alpha. line profile observations

    SciTech Connect

    Argo, H.V.

    1981-01-01

    A rocket borne experiment to measure the temperature structure of the inner solar corona via the doppler broadening of the resonance hydrogen Lyman-..cap alpha.. (lambda1216A) radiation scattered by ambient neutral hydrogen atoms was attempted during the 16 Feb 1980 solar eclipse. Two Nike-Black Brant V sounding rockets carrying instrumented payloads were launched into the path of the advancing eclipse umbra from the San Marco satellite launch platform 3 miles off the east coast of Kenya.

  2. Uhuru (SAS-1/Explorer 42)

    NASA Astrophysics Data System (ADS)

    Murdin, P.

    2000-11-01

    NASA satellite, launched from the San Marco platform off the Kenyan coast in 1970. The first satellite dedicated to x-ray astronomy. Completed an all-sky x-ray survey and studied individual sources. Discovered x-ray binaries, including Hercules X-1 and Centaurus X-1, and confirmed the variability of Cygnus X-1. Uhuru means `freedom' in Swahili. (See also SMALL ASTRONOMY SATELLITE, EXPLORER.)...

  3. Erratum: Weiss et al. 2015.

    PubMed

    Weiss, Maureen R; Phillips, Alison C; Kipp, Lindsay E

    2016-02-01

    Physical and Psychosocial Health Outcomes," in Ped Exerc Sci, 27(4), pp. 546-558, http://dx.doi.org/10.1123/pes.2015-0011, Kipp's affiliation was incorrectly listed as the Dept. of Kinesiology and Health Promotion, Lexington, KY. Kipp's correct affiliation is with the Dept. of Health and Human Performance, Texas State University, San Marcos, TX. We apologize for this error. PMID:26887610

  4. CGCI Investigators Reveal Comprehensive Landscape of Diffuse Large B-Cell Lymphoma (DLBCL) Genomes | Office of Cancer Genomics

    Cancer.gov

    Researchers from British Columbia Cancer Agency used whole genome sequencing to analyze 40 DLBCL cases and 13 cell lines in order to fill in the gaps of the complex landscape of DLBCL genomes. Their analysis, “Mutational and structural analysis of diffuse large B-cell lymphoma using whole genome sequencing,” was published online in Blood on May 22. The authors are Ryan Morin, Marco Marra, and colleagues.  

  5. Transvestites and transgressions: Panggagaya in Philippine gay cinema.

    PubMed

    Tolentino, R B

    2000-01-01

    Philippine cinema has long afforded spectators constructions of queerness not only deviating from Western queer theory but also from other continentally Asian homosexual traditions. Using as my primary text Lino Brocka's 1978 film My Father, My Mother, I examine how indigenous ideas of transsexuality and transgender are not only constructed by alternatively sexual images manufactured and appropriated by the Marcos regime, but how those sexual images construct and perpetuate class divisions as criteria of an ongoing Philippine sexual economy. PMID:11133142

  6. Determinación de la orientación global SAO-Hipparcos mediante una expansión en armónicos vectoriales

    NASA Astrophysics Data System (ADS)

    Cionco, R. G.; Vucetich, H.; Orellana, R.; Arias, E. F.

    En base a las diferencias de posición y movimientos propios de 101352 estrellas con posición SAO observadas por HIPPARCOS y utilizando la naturaleza vectorial de esas diferencias, determinamos 6 parámetros de orientación global (3 de rotación y 3 de desplazamiento axial), para los sistemas de referencia asociados a los marcos mencionados, mediante una descomposición en serie de armónicos vectoriales ortogonales.

  7. Agriculture near Uberlandia, State of Minas Gerais, Brazil, South America

    NASA Technical Reports Server (NTRS)

    1991-01-01

    Very large fields, typical of commercial and irrigated farmland, contrast with patchy upland agriculture in this view of southeastern Brazil (18.5S, 47.5W). A reservoir, just to the northeast of the city of Uberlandia, State of Minas Gerais, serves as the water source and is fed by the Rios Sao Marcos and the Rio Paranaiba. Near the bottom of the photo is circular feature with a plume of smoke thought to be a mining operation and smelter.

  8. Scientist to Expose Students to Wetlands Research

    NASA Technical Reports Server (NTRS)

    2002-01-01

    Dr. Marco Giardino, chief of the Applications Integration Division for NASA Stennis Space Center's Earth Science Applications Directorate, has been chosen by the JASON Project to be one of six host researchers for Disappearing Wetlands, which will run through the 2004-05 school year. In the photo, Giardino (left) interprets satellite imagery on the way to an archeological site near Lake Salvador, La., in November 2002. With him is his local guide, Michael Comardelle.

  9. Gamma ray satellite to be launched from Africa

    NASA Technical Reports Server (NTRS)

    Allaway, H. G.; Senstad, K.

    1972-01-01

    The announcement is presented of the launch of NASA's Small Astronomy Satellite B (SAS-B) on 2 Nov. 1972, to study gamma rays. The launch is to be from the Italian-operated San Marco Equatorial Range in the Indian Ocean for ease in acquiring an equatorial orbit. The spacecraft systems described include: stabilization and control, communication, and spark chamber gamma ray telescope. The results of Uhuru (Explorer 42) are also presented.

  10. Formation of the Resonant Populations in the Kuiper Belt

    NASA Astrophysics Data System (ADS)

    Griv, E.; Jiang, I.-G.

    2009-04-01

    Kuiper belt objects (KBOs) have most of their orbits within a thick disk outside that of Neptune as they are located around heliocentric distances in the range 35-50 AU. On the basis of their orbital elements KBOs can be grouped into distinct dynamical classes, namely the classical, the resonant, and the scattered ones. Resonant KBOs are trapped in mean-motion resonances with Neptune, mainly 3:2 orbital period resonance at 39.4 AU. The same resonance is also occupied by Pluto. In contrast, only a few KBOs are claimed to be associated with the inner 5:4 and 4:3 resonances (34.9 and 36.4 AU, respectively) and the outer 2:1 resonance (47.7 AU). Some other weak resonances are also clearly observed, for instance, 5:3 and 7:3 resonances (42 and 44 AU). Jiang & Yeh (2004, 2007) have proposed gas-drag-induced resonant capture in a protostellar disk analogous to the primordial solar nebula as a mechanism able to explain the dominant 3:2 resonant population observed in Kuiper belt objects. de La Fuente Marcos & de La Fuente Marcos (2008) further investigated the drag-induced mechanism numerically. Our significant contribution is just a hydrodynamic theory derivation of results obtained in Jiang & Yeh (2004, 2007) and de La Fuente Marcos & de La Fuente Marcos (2008) numerical simulations. The possibility of angular momentum and mass transport arising in the solar nebula at outer Lindblad orbital resonances is discussed. We show that the gas-drag-induced resonant process may lead to the formation of relatively narrow, ~ 0.2 AU, KBO rings. The number of KBOs captured into the 3:2 resonance may become a very large fraction of all objects, consistent with the observational results. The work was funded through the Israel Science Foundation, the Israeli Ministry of Immigrant Absorption, and by the Theoretical Institute for Advanced Research in Taiwan.

  11. Ectopic banking of amputated parts: a clinical review.

    PubMed

    Higgins, James P

    2011-11-01

    Since its first clinical description by Marco Godina in 1986, the technique of temporary ectopic banking of amputated parts has been employed in a growing body of reported cases. This installment provides a review of the reported cases in the international literature to date, focusing on our evolving understanding of clinical indications, operative timing, and surgical technical consideration. Two illustrative cases are provided to highlight these concepts. PMID:22036286

  12. SLICE/MARC-O: Description of Services. Second Revised Edition.

    ERIC Educational Resources Information Center

    Oklahoma State Dept. of Libraries, Oklahoma City.

    Following the discussions of: what is SLICE, what is MARC, what is MARC-O, and what is SLICE/MARC-O are descriptions of the five services offered by SLICE/MARC-O. These services are: (1) cataloging data search and print, (2) MARC record and search and copy, (3) standard S.D.I. current awareness, (4) custom S.D.I. current awareness and (5) SLICE…

  13. Life Sciences in the Ticino: Two Scientists - Two Stories.

    PubMed

    Fürst, Susanne Lauber

    2014-12-01

    Luca Varani, PhD, a group leader in Structural Biology at the Institute for Research in Biomedicine, Bellinzona, and Marco Brini, founder and CEO of EnvEve SA, in the Tecnopolo in Manno, describe their life sciences background, their careers and why they percieve their ideal situation being a basic scientist who wants to remain in science, or being an entrepreneur respectively. PMID:26508605

  14. The exaptive excellence of spandrels as a term and prototype

    PubMed Central

    Gould, Stephen Jay

    1997-01-01

    In 1979, Lewontin and I borrowed the architectural term “spandrel” (using the pendentives of San Marco in Venice as an example) to designate the class of forms and spaces that arise as necessary byproducts of another decision in design, and not as adaptations for direct utility in themselves. This proposal has generated a large literature featuring two critiques: (i) the terminological claim that the spandrels of San Marco are not true spandrels at all and (ii) the conceptual claim that they are adaptations and not byproducts. The features of the San Marco pendentives that we explicitly defined as spandrel-properties—their necessary number (four) and shape (roughly triangular)—are inevitable architectural byproducts, whatever the structural attributes of the pendentives themselves. The term spandrel may be extended from its particular architectural use for two-dimensional byproducts to the generality of “spaces left over,” a definition that properly includes the San Marco pendentives. Evolutionary biology needs such an explicit term for features arising as byproducts, rather than adaptations, whatever their subsequent exaptive utility. The concept of biological spandrels—including the examples here given of masculinized genitalia in female hyenas, exaptive use of an umbilicus as a brooding chamber by snails, the shoulder hump of the giant Irish deer, and several key features of human mentality—anchors the critique of overreliance upon adaptive scenarios in evolutionary explanation. Causes of historical origin must always be separated from current utilities; their conflation has seriously hampered the evolutionary analysis of form in the history of life. PMID:11038582

  15. ?Cuales son las amenazas o peligros volcanicos?

    USGS Publications Warehouse

    Myers, Bobbie; Brantley, Steven R.; Stauffer, Peter; Hendley, James W., II

    2000-01-01

    Los volcanes son capaces de producir numerosos peligros geologicos e hidrologicos. Los cientificos del Servicio Geologico de los EE. UU. (USGS, por sus siglas en ingles) y de otras instituciones alrededor del mundo estan estudiando los peligros de muchos de los centenares de volcanes activos y potencialmente activos del mundo. Estos cientificos vigilan muy de cerca la actividad de algunos de los volcanes mas peligrosos, por lo que estan preparados para alertar a las autoridades y/o a la poblacion en caso de que aumente sustancialmente la probabilidad de que ocurra una erupcion u otro evento peligroso.

  16. Concept of Operations for Deploying a Lander on the Secondary Body of Binary Asteroid 1996 FG3

    NASA Astrophysics Data System (ADS)

    Tardivel, Simon; Michel, P.; Scheeres, D.

    2012-10-01

    The European Space Agency is currently performing an assessment study of the MarcoPolo-R space mission, in the framework of the M3 class competition of its Cosmic Vision Program. MarcoPolo-R is a sample return mission to a primitive asteroid, whose baseline target is the binary asteroid 1996FG3. The baseline mission, including the sample, is focused on the primary of the binary system. To date, little has yet been considered for the investigation of the secondary, apart from remote observations from the spacecraft. However, MarcoPolo-R may carry an optional lander, and if such a lander could be accommodated it may be relevant to use it for a more detailed investigation of the secondary. This poster presents a strategy for deploying a lander using an unpowered trajectory towards the secondary. This ballistic deployment allows for the design of a light lander with minimum platform overhead and maximum payload. The deployment operations are shown to be very simple and require minimum preparation. The main spacecraft is set on an orbit that reaches a specific point near the binary system L2 Lagrange Point facing the far side of the secondary, about 220 meters from the secondary surface, with a relative speed of about 10cm/s. The lander is then jettisoned using a spring-release mechanism that sets it on an impact trajectory that robustly intersects with the secondary surface. On impact, the lander only needs to dissipate a small amount of kinetic energy in order to ensure that it is energetically and dynamically trapped on the surface. Considering errors on spacecraft GNC and on the spring-release mechanism, and very large uncertainties on the gravity field of the asteroids, the strategy presented here yields a successful landing in more than 99.9% of cases, while ensuring the absolute safety of the spacecraft before, during and after deployment operations.

  17. The case of the machinists' mutiny.

    PubMed

    Chew, W B

    1990-01-01

    "You can't be serious!" Mike Trail, the president and fourth-generation owner of Trail Manufacturing, stared at five older men standing in his office. "I'm afraid we are, Mike." Sandy, the most senior of the five, was polite but firm. "We won't switch over to the new equipment." Trail Manufacturing was a small Midwestern company trying to define itself in a new world of competition. Working with engineering chief Marco Duncan, Mike Trail, its young CEO, developed a program to revolutionize the company's manufacturing capability by installing six computerized machining centers. The $4 million automation program was proceeding smoothly, or at least it seemed to be, until the sixth of eight production teams, whose members included the company's most respected machinist, refused to continue participating. Mike canvased his colleagues for suggestions. "We can't let any screw machines remain in operation," Marco insisted. "The problem wasn't just old machines. The problem was--and is--the whole company. We need a clean break with the past." Shop manager Darrell Montgomery didn't necessarily disagree, but he worried about alienating Sandy. "You know what Sandy means to this place," he said. "If it wasn't for him, we never would have survived the startup." Bob Block, the company's CFO, went a step further. He questioned Marco's all-or-nothing vision and counseled compromise. "With half the new cells up, the screw machines are running a lot fewer jobs," he noted. "But they still account for over half our sales and even more of our profits. Maybe these guys are right." Four experts on change examine the crisis at Trail Manufacturing and debate Mike Trail's next step. PMID:10107958

  18. Calcium restores the macrophage response to nontypeable haemophilus influenzae in chronic obstructive pulmonary disease.

    PubMed

    Provost, Karin A; Smith, Miyuki; Arold, Stephen P; Hava, David L; Sethi, Sanjay

    2015-06-01

    Alveolar macrophages in chronic obstructive pulmonary disease (COPD) have demonstrated impaired bacterial phagocytosis and disordered cytokine secretion, which are calcium-dependent processes. We determined how calcium moderates the macrophage response to nontypeable Haemophilus influenzae (NTHI). We hypothesized that augmenting extracellular calcium during bacterial challenge would restore bacterial phagocytosis and cytokine secretion in monocyte-derived macrophages (MDMs) from subjects with COPD. We further determined whether restoration of pattern recognition and scavenger receptors correlated with the calcium-induced improvements in macrophage function. Monocytes were purified from whole blood from healthy control subjects (n = 20) and patients with moderate to severe COPD (n = 35), and cultured in suspension with granulocyte macrophage colony-stimulating factor to generate MDMs. The MDMs were incubated with fluorescently labeled NTHI with and without calcium lactate and calcium channel inhibitors. Phagocytosis efficiency was evaluated by flow cytometry. Supernatants were assayed for cytokines using bead array technology. Cell surface receptor expression was assayed by multicolor flow cytometry. Extracellular calcium significantly improved phagocytosis and cytokine secretion (IL-8, TNF-α, and macrophage inflammatory protein [MIP]-1α, and -1β) in COPD MDMs. NTHI challenge led to statistically significant reductions in CD16 (FcγRIII), and extracellular calcium up-regulated both CD16 and macrophage receptor with collagenous structure (MARCO). Specific calcium channel inhibitors abrogated calcium-mediated MARCO up-regulation and cytokine secretion. Extracellular calcium improved phagocytosis, restored innate cytokine secretion, and increased cell surface expression of bacterial recognition receptors, CD16 and MARCO. These observations support the therapeutic use of calcium to improve macrophage function in COPD to decrease exacerbations and chronic bacterial infection. PMID:25338285

  19. Cell proliferation and modulation of interaction of estrogen receptors with coregulators induced by ER? and ER? agonists.

    PubMed

    Evers, Nynke M; van den Berg, Johannes H J; Wang, Si; Melchers, Diana; Houtman, Ren; de Haan, Laura H J; Ederveen, Antwan G H; Groten, John P; Rietjens, Ivonne M C M

    2014-09-01

    The aim of the present study was to investigate modulation of the interaction of the ER? and ER? with coregulators in the ligand responses induced by estrogenic compounds. To this end, selective ER? and ER? agonists were characterized for intrinsic relative potency reflected by EC50 and maximal efficacy towards ER? and ER? mediated response in ER selective reporter gene assays, and subsequently tested for induction of cell proliferation in T47D-ER? cells with variable ER?/ER? ratio, and finally for ligand dependent modulation of the interaction of ER? and ER? with coregulators using the MARCoNI assay, with 154 unique nuclear receptor coregulator peptides derived from 66 different coregulators. Results obtained reveal an important influence of the ER?/ER? ratio and receptor selectivity of the compounds tested on induction of cell proliferation. ER? agonists activate cell proliferation whereas ER? suppresses ER? mediated cell proliferation. The responses in the MARCoNI assay reveal that upon ER? or ER? activation by a specific agonist, the modulation of the interaction of the ERs with coregulators is very similar indicating only a limited number of differences upon ER? or ER? activation by a specific ligand. Differences in the modulation of the interaction of the ERs with coregulators between the different agonists were more pronounced. Based on ligand dependent differences in the modulation of the interaction of the ERs with coregulators, the MARCoNI assay was shown to be able to classify the ER agonists discriminating between different agonists for the same receptor, a characteristic not defined by the ER selective reporter gene or proliferation assays. It is concluded that the ultimate effect of the model compounds on proliferation of estrogen responsive cells depends on the intrinsic relative potency of the agonist towards ER? and ER? and the cellular ER?/ER? ratio whereas differences in the modulation of the interaction of the ER? and ER? with coregulators contribute to the ligand dependent responses induced by estrogenic compounds. PMID:24923734

  20. Multi-walled carbon nanotubes injure the plasma membrane of macrophages

    SciTech Connect

    Hirano, Seishiro Kanno, Sanae; Furuyama, Akiko

    2008-10-15

    Carbon nanotubes (CNTs) are emerging nanotechnology materials which are likely to be mass-produced in the near future. However, prior to mass-production, certain health-related concerns should first be addressed. For example, when inhaled, the thin-fibrous shape and the biopersistent characteristics of CNTs may cause pulmonary diseases, in a manner similar to asbestos. In the present study, mouse macrophages (J774.1) were exposed to highly-purified multi-walled CNTs (MWCNTs, 67 nm) or to UICC crocidolite in order to evaluate the toxicity of these nano-size fibers. The cytotoxicity of MWCNTs was found to be higher than that of crocidolite. The toxic effect of MWCNTs was not affected by N-acetylcysteine, an antioxidant, or buthionine sulfoximine, a glutathione synthesis inhibitor. cDNA microarray analyses suggested that the cytotoxicity of MWCNTs could not be explained satisfactorily by either an increase or decrease of gene expression, although mRNA levels of some cytokines were slightly increased by MWCNTs. Moreover, MWCNTs did not significantly activate either MAP kinases such as ERK, JNK and p38, nor common apoptosis pathways such as caspase 3 and PARP. Electron microscopic studies indicated that MWCNTs associate with the plasma membrane of macrophages and disrupt the integrity of the membrane. Several proteins were found to adsorb onto MWCNTs when MWCNT-exposed macrophages were gently lysed. One of these proteins was macrophage receptor with collagenous structure (MARCO). MARCO-transfected CHO-K1 cells associated with MWCNTs more rapidly than mock-transfected cells. These results indicate that MWCNTs probably trigger cytotoxic effects in phagocytotic cells by reacting with MARCO on the plasma membrane and rupturing the plasma membrane.

  1. Multi-walled carbon nanotubes injure the plasma membrane of macrophages.

    PubMed

    Hirano, Seishiro; Kanno, Sanae; Furuyama, Akiko

    2008-10-15

    Carbon nanotubes (CNTs) are emerging nanotechnology materials which are likely to be mass-produced in the near future. However, prior to mass-production, certain health-related concerns should first be addressed. For example, when inhaled, the thin-fibrous shape and the biopersistent characteristics of CNTs may cause pulmonary diseases, in a manner similar to asbestos. In the present study, mouse macrophages (J774.1) were exposed to highly-purified multi-walled CNTs (MWCNTs, 67 nm) or to UICC crocidolite in order to evaluate the toxicity of these nano-size fibers. The cytotoxicity of MWCNTs was found to be higher than that of crocidolite. The toxic effect of MWCNTs was not affected by N-acetylcysteine, an antioxidant, or buthionine sulfoximine, a glutathione synthesis inhibitor. cDNA microarray analyses suggested that the cytotoxicity of MWCNTs could not be explained satisfactorily by either an increase or decrease of gene expression, although mRNA levels of some cytokines were slightly increased by MWCNTs. Moreover, MWCNTs did not significantly activate either MAP kinases such as ERK, JNK and p38, nor common apoptosis pathways such as caspase 3 and PARP. Electron microscopic studies indicated that MWCNTs associate with the plasma membrane of macrophages and disrupt the integrity of the membrane. Several proteins were found to adsorb onto MWCNTs when MWCNT-exposed macrophages were gently lysed. One of these proteins was macrophage receptor with collagenous structure (MARCO). MARCO-transfected CHO-K1 cells associated with MWCNTs more rapidly than mock-transfected cells. These results indicate that MWCNTs probably trigger cytotoxic effects in phagocytotic cells by reacting with MARCO on the plasma membrane and rupturing the plasma membrane. PMID:18655803

  2. El Sistema de Referencia Celeste convencional de la IAU

    NASA Astrophysics Data System (ADS)

    Arias, E. F.

    La Unión Astronómica Internacional (IAU) recomendó la adopción de un nuevo sistema de referencia celeste baricéntrico cuyo plano fundamental y origen de ascensiones rectas estén próximos, respectivamente, al ecuador y equinoccio dinámicos J2000.0. El nuevo sistema de referencia estará materializado por las posiciones J2000.0 de radiofuentes extragalácticas determinadas con la técnica de interferometría de larga línea de base (VLBI). El Working Group on Reference Frames de la IAU (WGRF) decidió adoptar (Grasse, 1995) al sistema de referencia celeste extragaláctico del Servicio Internacional de la Rotación Terrestre (IERS) como futuro sistema de referencia celeste convencional bajo el nombre International Celestial Reference System (ICRS) y encomendó su mantenimiento futuro al IERS. El marco de referencia que materializará al ICRS contiene posiciones precisas J2000.0 de más de 600 radiofuentes extragalácticas. Las coordenadas fueron ajustadas en una única solución VLBI en la cual se incluyeron todas las observaciones realizadas hasta octubre de 1995 con la técnica de adquisición de datos VLBI Mark III. Para minimizar los errores sistemáticos que pueden afectar la calidad del marco de referencia se introdujeron mejoras sustanciales en la modelización y en la selección de datos. Un subconjunto de objetos del marco de referencia se utilizó para referir las posiciones estelares determinadas con el satélite astrométrico Hipparcos al ICRS.

  3. Shock wave properties of anorthosite and gabbro. [to model hypervelocity impact cratering on planetary surfaces

    NASA Technical Reports Server (NTRS)

    Boslough, M. B.; Ahrens, T. J.

    1985-01-01

    Huyoniot data on San Gabriel anorthosite and San Marcos gabbro to 11 GPA are presented. Release paths in the stress-density plane and sound velocities are reported as determined from partial velocity data. Electrical interference effects precluded the determination of accurate release paths for the gabbro. Because of the loss of shear strength in the shocked state, the plastic behavior exhibited by anorthosite indicates that calculations of energy partitioning due to impact onto planetary surfaces based on elastic-plastic models may underestimate the amount of internal energy deposited in the impacted surface material.

  4. Shock wave properties of anorthosite and gabbro

    NASA Technical Reports Server (NTRS)

    Boslough, M. B.; Ahrens, T. J.

    1984-01-01

    Hugoniot data on San Gabriel anorthosite and San Marcos gabbro to 11 GPA are presented. Release paths in the stress-density plane and sound velocities are reported as determined from particl velocity data. Electrical interference effects precluded the determination of accurate release paths for the gabbro. Because of the loss of shear strength in the shocked state, the plastic behavior exhibited by anorthosite indicates that calculations of energy partitioning due to impact onto planetary surfaces based on elastic-plastic models may underestimate the amount of internal energy deposited in the impacted surface material.

  5. Austin Chalk boundaries bigger than Texas

    SciTech Connect

    Calhoun, J.

    1980-11-01

    The Austin Chalk is a carbonate limestone which has major outcropping near Austin, Texas. Around Austin, San Antonio, and San Marcos it finds its major expression in the so-called Balcones Escarpment, a jutting limestone promontory that divides the Texas hill country from the Black Gumbo Farmland to the east, and forms one of the longest, most noticeable geologic features in the state. The Chalk is known to run through the entire Gulf Coast Littoral - Louisiana, Mississippi, and Alabama. A map shows the locations of the major uplifts, downwarps, fault zones, and tectonic belts in the Austin Chalk play.

  6. Visual Photometry from CCD Observations of the Nova V1178 SCO

    NASA Astrophysics Data System (ADS)

    Carlos, R.

    In this poster we present some observations of the Nova V1178 Sco made with camera CCD coupled to a telescope MEADE of 8 inches, the obtained results are in agreement with other observations carried out by stars' variables observers' groups. We also show mainly the work that we come carrying out for the construction and implementation of a small astronomical observatory for the university of San Marcos in Lima, Peru. The place of the future observatory this located at 4 hours of the city of the Cuzco and a height of approximately 4.000 about of sea level.

  7. Economic impact of stimulated technological activity. Part 1: Overall economic impact of technological progress: Its measurement

    NASA Technical Reports Server (NTRS)

    1971-01-01

    Investigations were performed at the national economic level to explore the aggregate effects of technological progress on economic growth. Inadequacies in existing marco-economic yardsticks forced the study to focus on the cost savings effects achieved through technological progress. The central questions discussed in this report cover: (1) role of technological progress in economic growth, (2) factors determining the rate of economic growth due to technological progress; (3) quantitative measurements of relationships between technological progress, its determinants, and subsequent economic growth; and (4) effects of research and development activities of the space program. For Part 2, see N72-32174.

  8. Spent filter packaging for long term storage and disposal

    SciTech Connect

    Duberville, T.M.; Miller, C.

    2007-07-01

    This paper will discuss filter packaging experience using spent filter transfer casks, a filter shear and the NUKEM macro-encapsulation process. Marco-encapsulation of spent filters in cement has provided sufficient shielding to enable filter containers to be shipped in less expensive IP-2 casks. The lower dose rate and higher density also off-sets disposal rates at Barnwell based on mass. No re-dewatering of encapsulated filter containers is required after a period of long term storage and encapsulation eliminates the possibility of gas generation from filters during storage. Encapsulation can be performed on filters loaded into poly HICs or carbon steel liners. (authors)

  9. Seamounts and ferromanganese crusts within and near the U.S. EEZ off California - Data for RV Farnella cruise F7-87-SC

    USGS Publications Warehouse

    Hein, James R.; Reid, Jane A.; Conrad, Tracey A.; Dunham, Rachel E.; Clague, David A.; Schulz, Marjorie S.; Davis, Alice S.

    2010-01-01

    The purpose of this report is to present and briefly describe ship-board and laboratory data for a U.S. Geological Survey (USGS) research cruise aboard the RV Farnella that took place December 3-21, 1987 (cruise F7-87-SC). The purpose of the cruise was to survey seamounts and ferromanganese crusts within and near the U.S. Exclusive Economic Zone (EEZ) off California. Eight seamounts were studied - Rodriguez, San Marcos, Adam, Hoss, Little Joe, Ben, Flint, and Jasper. A geophysical survey of Jasper Seamount took place, but that seamount was not sampled; whereas Adam and Hoss Seamounts were sampled, but not surveyed with geophysics lines.

  10. Aula Verde: art as experience in community-based environmental education.

    PubMed

    Abarca, Marco A

    2010-01-01

    After winning a class-action lawsuit against unconstitutional prison conditions in Puerto Rico, Marco Abarca managed to direct part of the fine monies accumulated throughout years of litigation toward an investment that would improve the living conditions in one of the largest and poorest housing projects in Puerto Rico. With the participation of parolees and probationers, he began to transform a mosquito-infested badland into a natural haven. Then, with the help of science educators, the group designed a workshop for elementary school children on urban ecology. As the participants organized, what developed was a community-based, self-employed enterprise known as Aula Verde. PMID:20391620

  11. Conocimiento de Energía: Principios Esenciales y Conceptos Fundamentales para la Educación de Energía

    SciTech Connect

    2014-06-01

    This is the Spanish version of our Energy Literacy guidebook. Esta guía presenta conceptos de energía que, cuando se entienden y se aplican, ayudan a individuos y a comunidades a tomar decisiones sobre la energía con conocimiento de causa. No es un currículo sino que ofrece un marco sobre el cual puede basarse un plan de estudios. La guía se dirige a cualquier persona que participe en la educación de energía.

  12. Impact spallation experiments - Fracture patterns and spall velocities

    NASA Technical Reports Server (NTRS)

    Polanskey, Carol A.; Ahrens, Thomas J.

    1990-01-01

    The spall velocities produced by nine experimental impacts of 1 to 6.5 km/sec into San Marcos gabbro targets, using projectiles of Fe, Al, Pb, and basalt of various sizes, have been measured in conjunction with fragment-velocity high-speed filmings of the events. A detailed comparison is made between measured spall velocities and those predicted by the model of Melosh (1984), with a view to the compatibility of small-scale results and large planetary impacts. Attention is also given to the patterns of internal fracture generated by impact within the targets.

  13. Impact spallation experiments - Fracture patterns and spall velocities

    SciTech Connect

    Polanskey, C.A.; Ahrens, T.J. California Institute of Technology, Pasadena )

    1990-09-01

    The spall velocities produced by nine experimental impacts of 1 to 6.5 km/sec into San Marcos gabbro targets, using projectiles of Fe, Al, Pb, and basalt of various sizes, have been measured in conjunction with fragment-velocity high-speed filmings of the events. A detailed comparison is made between measured spall velocities and those predicted by the model of Melosh (1984), with a view to the compatibility of small-scale results and large planetary impacts. Attention is also given to the patterns of internal fracture generated by impact within the targets. 29 refs.

  14. Environmental statement for National Aeronautics and Space Administration, Office of Space Science, launch vehicle and propulsion programs

    NASA Technical Reports Server (NTRS)

    1972-01-01

    NASA OSS Launch Vehicle and Propulsion Programs are responsible for the launch of approximately 20 automated science and applications spacecraft per year. These launches are for NASA programs and those of other U. S. government agencies, private organizations, such as the Comsat Corporation, foreign countries, and international organizations. Launches occur from Cape Kennedy, Florida; Vandenberg Air Force Base, California; Wallops Island, Virginia; and the San Marco Platform in the Indian Ocean off Kenya. Spacecraft launched by this program contribute in a variety of ways to the control of and betterment of the environment. Environmental effects caused by the launch vehicles are limited in extent, duration, and intensity and are considered insignificant.

  15. APL workers install CRIS on the Advanced Composition Explorer (ACE) in SAEF-2

    NASA Technical Reports Server (NTRS)

    1997-01-01

    Workers from the Johns Hopkins University's Applied Physics Laboratory (APL) install the Cosmic Ray Isotope Spectrometer (CRIS) on the Advanced Composition Explorer (ACE) spacecraft in KSC's Spacecraft Assembly and Encapsulation Facility-2 (SAEF-2). From left, are Al Sadilek, Marcos Gonzalez and Cliff Willey. CRIS is one of nine instruments on ACE, which will investigate the origin and evolution of solar phenomenon, the formation of the solar corona, solar flares and the acceleration of the solar wind. ACE was developed for NASA by the APL. The spacecraft is scheduled to be launched Aug. 21 aboard a two-stage Delta II 7920-8 rocket from Space Launch Complex 17, Pad A.

  16. Commission 20: Position and Motion of Minor Planets, Comets and Satellites

    NASA Astrophysics Data System (ADS)

    Valsecchi, Giovanni B.; Fernandez, Julio; Bowell, Edward L. G.; Arlot, Jean-Eudes; Bowell, Edward L. G.; Chernetenko, Yulia A.; Chesley, Steven R.; Lazzaro, Daniela; Lemaitre, Anne; Marsden, Brian G.; Muinonen, Karri; Rickman, Hans; Tholen, David J.; Yoshikawa, Makoto

    2007-12-01

    A total of 16 among the new IAU members have asked to join Commission 20; they are: Jerome Berthier, Nicholas J. Cooper, Marco Delb, Romina P. Di Sisto, Michael W. Evans, Tetsuharu Fuse, Ludmila Hudkova, Yurij N. Krugly, Elena N. Polyakhova, Zhanna Pozhalova, Alessandro Rossi, Qi Rui, Jonathan D. Shanklin, Slawomira E. Szutowicz, Gino Tuccari and Hong-Suh Yim. Moreover, two requests to join the Commission have been received by astronomers that are already IAU members: Peter De Cat and Ricardo A. Gil-Hutton.

  17. Representing object oriented specifications and designs with extended data flow notations

    NASA Technical Reports Server (NTRS)

    Buser, Jon Franklin; Ward, Paul T.

    1988-01-01

    The issue of using extended data flow notations to document object oriented designs and specifications is discussed. Extended data flow notations, for the purposes here, refer to notations that are based on the rules of Yourdon/DeMarco data flow analysis. The extensions include additional notation for representing real-time systems as well as some proposed extensions specific to object oriented development. Some advantages of data flow notations are stated. How data flow diagrams are used to represent software objects are investigated. Some problem areas with regard to using data flow notations for object oriented development are noted. Some initial solutions to these problems are proposed.

  18. Chili Cookoff 2016: The Largest Ever | Poster

    Cancer.gov

    Marco Johnson decided to bring “the big guns” to the 13th annual Protective Services Chili Cookoff—his wife, Jill. The strategy paid off because Johnson’s chili recipe won first place, standing out against some stiff competition. Johnson, a shuttle bus driver for Protective Services, added his own special touches to the recipe developed by his wife; he used Kielbasa as the main ingredient and increased the smoky flavor, hence the name Jill’s Smoky Kielbasa Chili. The recipe also included crispy bacon, hot pepper seasonings, and a variety of diced tomatoes, from roasted to hot.

  19. Impact induced damage beneath craters

    NASA Astrophysics Data System (ADS)

    Xia, Kaiwen; Ahrens, Thomas J.

    Ackermann et al. (1975) described the subsurface structure of Meteor Crater and identified a fractured rock zone extending to about 1 km deep. The depth of the fractured/damage zone can be used to extract information about the impact cratering process. We impacted rock samples (San Marcos gabbro) in the laboratory and imaged the damage structure using both dicing and tomography methods. We propose a simple model to describe the damage zone depth based on the laboratory measurements. The model agrees well with other methods for the estimation of the projectile size of Meteor Crater and it may be used for estimates of damage around craters of other planets and moons.

  20. The Scout Launch Vehicle program

    NASA Technical Reports Server (NTRS)

    Foster, L. R., Jr.; Urash, R. G.

    1981-01-01

    The Scout Launch Vehicle Program to utilize solid propellant rockets by the DOD and to provide a reliable, low cost vehicle for scientific and applications aircraft is discussed. The program's history is reviewed and a vehicle description is given. The Vandenberg Air Force Base and the San Marco launch sites are described, and capabilities such as payload weight, orbital inclinations, payload volume and mission integration time spans are discussed. Current and future plans for improvement, including larger heat shields and individual rocket motors are also reviewed.

  1. Mapa Geologico de Venezuela a Escala 1:750,000

    USGS Publications Warehouse

    Hackley, Paul C.; Urbani, Franco; Karlsen, Alex W.; Garrity, Christopher P.

    2006-01-01

    Se presenta un mapa geologico digital de Venezuela sobre un fondo de relieve sombreado. Los datos geologicos e hidrologicos del norte del rio Orinoco proceden de la digitalizacion de mapas geologicos en papel a escala 1:500.000. Estos datos fueron integrados con el mapa geologico digital del Escudo de Guayana Venezolano, a su vez derivado de hojas en papel a escala 1:500.000. La informacion sobre los tipos de fallas mostrados en el mapa es igual que en las fuentes originales. Los poligonos geologicos fueron atribuidos por edad, litologia y nombre de la unidad siguiendo el Codigo geologico de Venezuela. Se incorporaron revisiones significativas de la geologia de la Cordillera de la Costa a partir de las nuevas hojas integradas a escala 1:25.000. Toda esta informacion geologico-estructural se sobrepuso a una imagen de relieve sombreado, producida por el procesamiento de los datos de radar interferometrico con 90 m (3 arcosegundos) de resolucion espacial obtenidos por la mision topografica de radar del transbordador espacial (SRTM). Las areas de la base de datos del SRTM carentes de informacion fueron llenadas por medio de la interpolacion de los datos de las celdas adyacentes. Para producir la imagen de relieve sombreado se uso una direccion de iluminacion de 315 deg con un angulo de 65 deg sobre el horizonte. La proyeccion usada en el mapa es conica equidistante, con latitudes de 4 y 9 deg norte como paralelos estandar y una longitud de 66 deg al oeste como meridiano central. Los datos en el mapa proceden primordialment de hojas a escala 1:500.000 y el producto esta preparado para una impresion optima en escala 1:750.000. Los usuarios pueden obtener ampliaciones mayores, sin embargo no se garantiza la precision del mapa a escalas mas detalladas. Especialmente en la region de Guayana, al sobreponer los mapas geologicos sobre la reciente imagen SRTM, se notan grandes discrepancias no sistematicas tanto en contactos como en fallas. Esto es debido a que los mapas geologicos de Guayana tienen como base topografica las imagenes de radar de vision lateral (SLAR), con muy control de campo de los a?os 1970's. La correccion de estos desfases esta planificada para el futuro.

  2. Dynamics and History of Mars Trojans

    NASA Astrophysics Data System (ADS)

    Cuk, Matija; Hamilton, D. P.

    2013-10-01

    Mars is the only terrestrial planet known to have long-term stable Trojan coorbitals. Recently, Christou (2013) and De la Fuente Marcos & De la Fuente Marcos (2013) have shown that several smaller Mars Trojans belong to a dynamical cluster centered on (5261) Eureka. While some of non-cluster Mars Trojans have colors distinct from Eureka (Rivkin et al. 2007), it is not clear if the cluster itself is compositionally homogeneous. Given that cluster member orbits should diverge over the age of the Solar System (Scholl et al. 2005), a recent origin of the cluster is likely. Our preliminary work indicates that the cluster could not have been formed through the slow dissipation of the Yarkovsky effect, in agreement with past results of Fleming & Hamilton (2000). Hence, our current expectation is that the cluster is collisional, and we expect to present an estimate of the age of the cluster at the meeting, based on long-term integrations of the cluster's dynamical diffusion. We will also discuss possible origin scenarios for Mars Trojans. It is now known that the Mars-crosser population was significantly larger in the past (Cuk 2012), and some Mars-crossers can spend time as temporary Trojans. Mechanisms of temporary Trojan stabilization include dynamical chaos and collisions (with some fragments of temporary Trojans becoming long-term stable). These and other routes will be tested using analytical arguments and numerical simulations. This work is supported by NASA PGG award NNX12AO41G.

  3. Brain activation associated with active and passive lower limb stepping

    PubMed Central

    Jaeger, Lukas; Marchal-Crespo, Laura; Wolf, Peter; Riener, Robert; Michels, Lars; Kollias, Spyros

    2014-01-01

    Reports about standardized and repeatable experimental procedures investigating supraspinal activation in patients with gait disorders are scarce in current neuro-imaging literature. Well-designed and executed tasks are important to gain insight into the effects of gait-rehabilitation on sensorimotor centers of the brain. The present study aims to demonstrate the feasibility of a novel imaging paradigm, combining the magnetic resonance (MR)-compatible stepping robot (MARCOS) with sparse sampling functional magnetic resonance imaging (fMRI) to measure task-related BOLD signal changes and to delineate the supraspinal contribution specific to active and passive stepping. Twenty-four healthy participants underwent fMRI during active and passive, periodic, bilateral, multi-joint, lower limb flexion and extension akin to human gait. Active and passive stepping engaged several cortical and subcortical areas of the sensorimotor network, with higher relative activation of those areas during active movement. Our results indicate that the combination of MARCOS and sparse sampling fMRI is feasible for the detection of lower limb motor related supraspinal activation. Activation of the anterior cingulate and medial frontal areas suggests motor response inhibition during passive movement in healthy participants. Our results are of relevance for understanding the neural mechanisms underlying gait in the healthy. PMID:25389396

  4. The Effect of Size on Ag Nanosphere Toxicity in Macrophage Cell Models and Lung Epithelial Cell Lines Is Dependent on Particle Dissolution

    PubMed Central

    Hamilton, Raymond F.; Buckingham, Sarah; Holian, Andrij

    2014-01-01

    Silver (Ag) nanomaterials are increasingly used in a variety of commercial applications. This study examined the effect of size (20 and 110 nm) and surface stabilization (citrate and PVP coatings) on toxicity, particle uptake and NLRP3 inflammasome activation in a variety of macrophage and epithelial cell lines. The results indicated that smaller Ag (20 nm), regardless of coating, were more toxic in both cell types and most active in the THP-1 macrophages. TEM imaging demonstrated that 20 nm Ag nanospheres dissolved more rapidly than 110 nm Ag nanospheres in acidic phagolysosomes consistent with Ag ion mediated toxicity. In addition, there were some significant differences in epithelial cell line in vitro exposure models. The order of the epithelial cell lines sensitivity to Ag was LA4 > MLE12 > C10. The macrophage sensitivity to Ag toxicity was C57BL/6 AM > MARCO null AM, which indicated that the MARCO receptor was involved in uptake of the negatively charged Ag particles. These results support the idea that Ag nanosphere toxicity and NLRP3 inflammasome activation are determined by the rate of surface dissolution, which is based on relative surface area. This study highlights the importance of utilizing multiple models for in vitro studies to evaluate nanomaterials. PMID:24758926

  5. Paleomagnetism of the Central Atlantic Magmatic Province in the Algarve basin, Portugal: First insights

    NASA Astrophysics Data System (ADS)

    Font, Eric; Fernandes, Susana; Neres, Marta; Carvallo, Claire; Martins, Línia; Madeira, José; Youbi, Nasrrddine

    2015-11-01

    We present new rock magnetic and paleomagnetic data of the Central Atlantic Magmatic Province (CAMP) lavas cropping out in the Algarve basin (southern Portugal). Our results show that the magnetic mineralogy of the selected samples is primary and dominated by an assemblage of single-domain (SD) to multi-domain (MD) Ti-poor titanomagnetites. All samples carry a characteristic remanent magnetization of normal (positive) magnetic polarity, similarly to other circum-Atlantic CAMP lava sequences. Except for the sites located in the central part of the Algarve basin, site-based mean directions (5 sites, Group A) are comparable to the giant Messejana dyke's directions, suggesting that both lava flows and dyke were emplaced during the same geological interval (~ 200 Ma). However, sites located in the central part of the basin (4 sites; Group B), just east of the São Marcos-Quarteira fault zone, show a systematic discrepancy in the declination values, which is indicative of a significant vertical-axis rotation that we estimated to be ~ 30° clockwise. We suggest that the observed clockwise vertical-axis rotation was produced by a Riedel dextral shear zone of the São Marcos-Quarteira faults acting during the N-S compression that affected the Southern Portuguese margin in the Cenozoic. Our results provide important insights to unravel the complex history of the Algarve basin since the Mesozoic.

  6. Horizontal drilling in the Austin Chalk: Stratigraphic factors

    SciTech Connect

    Durham, C.O. Jr. ); Bobigian, R.A. )

    1990-05-01

    Horizontal drilling has renewed interest in the Austin chalk in south-central Texas. Large fields on opposite sides of the San Marcos arch Giddings to the northeast and Pearsall to the southwest were active with vertical drilling 10 years ago. Giddings' 4,500 Austin wells produced 209 million BO and 934 bcfg of gas through 1988; Pearsall's 1,440 wells produced 57 million BO and 35 bcfg of gas. Most vertical wells were completed, 20% were economic successes, 40% were marginal, 40% were uneconomic due to uneven areal distribution of near-vertical fractures and small faults, which provide reservoirs in otherwise tight chalk. Horizontal drilling, led by Amoco in Giddings and Oryx in Pearsall, enhances the chances of encountering the fractures by drilling perpendicular to the fracture trend. Horizontal drilling requires preselection of the stratigraphic horizon to be penetrated. One must understand the variable Austin stratigraphy to choose the zone with the most brittle character and best matrix porosity, both reduced by increased clay content. Chalk 130 ft thick on the San Marcos arch thickens to 600 to 800 ft in central Giddings field where middle marl separates lower and upper chalk Northeastward only lower chalk is preserved beneath a post-Austin submarine channel. The Austin thickens to 300-500 ft in Pearsall field where middle member ash beds separate lower and upper chalk inhibiting vertical reservoir communication. Locally, on the Pearsall arch, ash is missing, lower chalk thickens, and upper chalk thins.

  7. MicroRNA-155 is required for clearance of Streptococcus pneumoniae from the nasopharynx.

    PubMed

    Verschoor, Chris P; Dorrington, Michael G; Novakowski, Kyle E; Kaiser, Julie; Radford, Katherine; Nair, Parameswaran; Anipindi, Varun; Kaushic, Charu; Surette, Michael G; Bowdish, Dawn M E

    2014-11-01

    Pneumonia caused by Streptococcus pneumoniae is a major cause of death and an economic burden worldwide. S. pneumoniae is an intermittent colonizer of the human upper respiratory tract, and the ability to control asymptomatic colonization determines the likelihood of developing invasive disease. Recognition of S. pneumoniae by resident macrophages via Toll-like receptor 2 (TLR-2) and the macrophage receptor with collagenous structure (MARCO) and the presence of interleukin-17 (IL-17)-secreting CD4(+) T cells are required for macrophage recruitment and bacterial clearance. Despite the fact that the primary cellular effectors needed for bacterial clearance have been identified, much of the underlying regulatory mechanisms are unknown. Herein, we demonstrate that the small, noncoding RNA microRNA-155 (mir-155) is critical for the effective clearance of S. pneumoniae. Our studies show that mir-155-deficient mice maintain the ability to prevent acute invasive pneumococcal infection but have significantly higher bacterial burdens following colonization, independently of macrophage recognition by TLR-2, MARCO expression, or bactericidal capacity. The observed defects in bacterial clearance parallel reduced IL-17A and gamma interferon CD4(+) T-cell responses in vivo, lower IL-17A mRNA levels in the nasopharynx, and a reduced capacity to induce Th17 cell polarization. Given that knockout mice are also limited in the capacity to generate high-titer S. pneumoniae-specific antibodies, we conclude that mir-155 is a critical mediator of the cellular effectors needed to clear primary and secondary S. pneumoniae colonizations. PMID:25156727

  8. [Health and primary education in the regenerationist ideology at the open educational institution].

    PubMed

    Ballester, R; Perdiguero, E

    1998-01-01

    The objective of this work is to reconstruct the discourse of the authors who published about issues establishing links between health and primary education in the Boletin de la Institucion Libre de Ensenanza at the time of the Spanish colonial crisis in 1898. This source has been chosen due to its relevance to Spanish pedagogical renovation. Physical education was taken as a model for analysis for two reasons: firstly, it is the aspect that received the most attention; secondly, it became the engine for change in the renovation programme. In addition, its holistic nature was intended to lead to the new citizen that was needed by the country after the loss of the colonies. PMID:11620570

  9. [From the old headquarters of the Diretoria Geral de Saúde Pública (DGSP) to the Instituto Nacional do Câncer (Inca)].

    PubMed

    de Oliveira, Tadeu Benedito

    2007-01-01

    The old headquarters of the Diretoria Geral de Saúde Pública (DGSP), located on Rua do Resende #128, and the Conjunto Arquitetônico Histórico de Manguinhos da Fiocruz (Manguinhos-Fiocruz Historical Architectural Complex) are contemporary buildings built by the initiative of Oswaldo Cruz and projects by Luiz Moraes Júnior. The old DGSP is as important as the so-called Instituto Oswaldo Cruz (IOC) then, now Fundação Oswaldo Cruz (Fiocruz) for the introduction and institucionalization of public health policies in Brasil. We describe the building project of the DGSP facilities, its evolution, transformations, and the process of becoming part of the Historic Heritage. PMID:17645147

  10. El Planetario Móvil de la Municipalidad de la ciudad de Córdoba

    NASA Astrophysics Data System (ADS)

    Suárez, F. E.; Campos, M.; Goldes, G. V.; Carranza, G. J.; Romero, R.; Juri, H. O.

    Se describen las características y operatoria del nuevo Planetario Móvil. Se trata de un equipamiento de propiedad de la Municipalidad de la Ciudad de Córdoba que es operado por personal y en el predio de la Universidad, en virtud de un convenio suscripto entre ambas instituciones. El planetario consta de una cúpula inflable y de un proyector con programas alternativos que incluyen temas de astronomía, geografía, biología y medio ambiente, entre otros. En la actualidad opera en las instalaciones del Pabellón Argentina de la Ciudad Universitaria y recibe delegaciones escolares de todo el territorio provincial. El Planetario Móvil es parte de un proyecto más amplio de divulgación científica en el cual interactúan la Universidad y el Municipio.

  11. Predicting visual search for abnormal color vision with perceptual models of color deficient vision.

    PubMed

    de Almeida, Vasco; Santos, Jorge; Linhares, João; João, Catarina; Nascimento, Sérgio

    2015-01-01

    Performance on a visual search task depends on the conspicuity of the target in relation to the distracters. If these have different colors, performance can reveal the perceptual structure of the color space. The aim of this work was to test how perceptual models of color deficiencies predict the performance of dichromats and anomalous trichromats on a search paradigm. Brettel's transformation and a transformation of the stimuli based on the anomalous photopigments proposed by DeMarco et al. were the models used. Stimuli were presented on a calibrated CRT monitor driven by a VSG2/3 graphics card. The stimuli consisted of one target (diamond shaped) among 150 distracters (squares, circles and triangles). The target was always displayed at 1-deg from the center of the screen and the distracters were randomly spread across 8x7 deg. In the normal condition, the colors of the target and distracters were selected in 48 directions around standard illuminant C in CIE L*a*b* color space and the hue angle between target and distracter was always 60-deg. All distracters had the same color but randomized luminance in the range 9.5-17 cd/m2. Observers were instructed to find a diamond-shaped target among the distracters and signal its presence as quickly as possible using a response box. The experiment was carried out by three deuteranopes, five protanopes, four deuteranomalous and three protanomalous. In the simulation condition, corresponding to Brettel's and DeMarco's transformation of the stimuli of the normal condition, seven normal color observers participated in the experiment. Results show high correlation for deuteranopes (r=0.82) and protanopes (r=0.83) and low correlation for deuteranomalous (r=0.45) and protanomalous (r=0.15). Additionally, both dichromats and anomalous trichromats took longer than normal observers tested with the simulated stimuli. These results suggest that Brettel's model predicts well dichromats perception and DeMarco transformation failed to predict anomalous trichromats perception. Meeting abstract presented at VSS 2015. PMID:26326999

  12. Particle velocity experiments in anorthosite and gabbro

    NASA Technical Reports Server (NTRS)

    Boslough, M. B.; Ahrens, T. J.

    1984-01-01

    Shock wave experiments were conducted in San Gabriel anorthosite and San Marcos gabbra 10 11 GPa using a 40 mm-borne propellant gun. Particle velocities were measured directly at several points in each target by means of electromagnetic gauges. Hugoniot states were calculated by determining shock-transit time from the gauge records. Sound speeds indicate a loss of shear strength upon sock compression for both rocks, with the strength loss persisting upon release to zero stress om the anorthosite. Stress-density release paths in the anorthosite indicate possible transformation of albite to jadeite + (quartz or coesite), with the amount of material transformed increasing as a function of shock stress. Electrical interferene effects in the gabbro precluded the determination of accurate release paths for the rock.

  13. (Hydroelectric project in Costa Rican rural electric generation and transmission)

    SciTech Connect

    Waddle, D.B.

    1989-11-28

    On November 6, 1989, I left for San Jose, Costa Rica. My visit was set to accomplish two activities. The first activity was a follow-on mission to gather additional information on a newly identified small hydroelectric project, in support of a rural electric generation and transmission cooperative performed for the Renewable Energy Applications and Training project. Data on stream flows, soils, geologic, and topographic information was gathered for Rio San Lorenzo, near Quesada. A reconnaissance level survey was performed for Rio Naranjillo, a river near San Marcos. The second part of the visit was dedicated to interaction with ICE, the electric utility, discussing plans to establish a comprehensive efficiency program in Costa Rica. I returned to Oak Ridge on November 16, 1989.

  14. An integrated model supporting histological and biometric responses as predictive biomarkers of fish health status

    SciTech Connect

    Torres Junior, Audalio Rebelo; Sousa, Débora Batista Pinheiro; Neta, Raimunda Nonata Fortes Carvalho

    2014-10-06

    In this work, an experimental system of histological (branchial lesions) biomarkers and biometric data in catfish (Sciades herzbergii) was modeled. The fish were sampled along known pollution areas (S1) and from environmental protect areas (S2) in São Marcos' Bay, Brazil. Gills were fixed in 10% formalin and usual histological techniques were used in the first gill arch right. The lesions were observed by light microscopy. There were no histopathological changes in animals captured at reference site (S1). However, in the catfish collected in the potentially contaminated area (S2) was observed several branchial lesions, such as lifting of the lamellar epithelium, fusion of some secondary lamellae, hypertrophy of epithelial cells and lamellar aneurysm. The analysis using the biometric data showed significant differences, being highest in fish analyzed in the reference area. This approach revealed spatial differences related with biometric patterns and morphological modifications of catfish.

  15. Final Scientific EFNUDAT Workshop

    ScienceCinema

    None

    2011-10-06

    The Final Scientific EFNUDAT Workshop - organized by the CERN/EN-STI group on behalf of n_TOF Collaboration - will be held at CERN, Geneva (Switzerland) from 30 August to 2 September 2010 inclusive.EFNUDAT website: http://www.efnudat.euTopics of interest include: Data evaluationCross section measurementsExperimental techniquesUncertainties and covariancesFission propertiesCurrent and future facilitiesInternational Advisory Committee: C. Barreau (CENBG, France)T. Belgya (IKI KFKI, Hungary)E. Gonzalez (CIEMAT, Spain)F. Gunsing (CEA, France)F.-J. Hambsch (IRMM, Belgium)A. Junghans (FZD, Germany)R. Nolte (PTB, Germany)S. Pomp (TSL UU, Sweden)Workshop Organizing Committee: Enrico Chiaveri (Chairman)Marco CalvianiSamuel AndriamonjeEric BerthoumieuxCarlos GuerreroRoberto LositoVasilis VlachoudisWorkshop Assistant: Graldine Jean

  16. A global thermospheric model based on mass spectrometer and incoherent scatter data MSIS. I - N2 density and temperature

    NASA Technical Reports Server (NTRS)

    Hedin, A. E.; Reber, C. A.; Newton, G. P.; Spencer, N. W.; Salah, J. E.; Evans, J. V.; Kayser, D. C.; Alcayde, D.; Bauer, P.; Cogger, L.

    1977-01-01

    Measurements of neutral nitrogen density from mass spectrometers on five satellites (AE-B, Ogo 6, San Marco 3, Aeros A, and AE-C) and neutral temperatures inferred from incoherent scatter measurements at four ground stations are combined to produce a model of thermospheric neutral temperatures and nitrogen densities similar to the Ogo 6 empirical model (Hedin et al., 1974). This global model is designated MSIS (mass spectrometer and incoherent scatter). The global average temperature, the annual temperature variation, lower bound density, and lower bound temperature are discussed. The data set covers the time period from the end of 1965 to mid-1975 and also a wide range of solar activities. Diurnal and semidiurnal variations in lower bound density and temperature are considered, as is magnetic activity.

  17. A global thermospheric model based on mass spectrometer and incoherent scatter data MSIS. II - Composition

    NASA Technical Reports Server (NTRS)

    Hedin, A. E.; Reber, C. A.; Newton, G. P.; Spencer, N. W.; Brinton, H. C.; Mayr, H. G.; Potter, W. E.

    1977-01-01

    Measurements of O, He, and Ar from neutral gas mass spectrometers on four satellites (Ogo 6, San Marco 3, Aeros A, and AEC-C) and inferred oxygen and hydrogen densities from an ion mass spectrometer on AE-C have been combined with a neutral temperature and nitrogen density model to produce a global model of thermospheric composition in terms of inferred variations at 120 km. The data set covers the time period from mid-1969 to mid-1975. The MSIS (mass spectrometer and incoherent scatter data) model is compared with the Ogo 6 model (Hedin et al., 1974). Ar variations at 120 km tend to be in phase with temperature variations and inverse to the He, O, and H variations.

  18. Poetry and the brain: Cajal's conjectures on the psychology of writers.

    PubMed

    Triarhou, Lazaros Constantinos; Vivas, Ana B

    2009-01-01

    In 1902, Santiago Ramón y Cajal (1852-1934), the father of modern neuroscience and a 1906 Nobel laureate, contributed a preface to a book of poems by his fellow countryman, Spanish poet and dramatist Marcos Zapata (1844-1914). In that uncustomary-for his neuroscience followers-essay, Cajal unfolds his ideas on the literary genres of drama and comedy in relation to the workings of the human mind and sentiments. The same text was reissued almost half a century later in Spain and in Argentina under the title The Psychology of Artists. We present an English version of Cajal's essay, which may be of interest to both humanists and biologists, and which further denotes the celebrated neuroanatomist's attempt at understanding the mystery of the human mind. PMID:19168946

  19. Temporal analyses of Salmonellae in a headwater spring ecosystem reveals the effects of precipitation and runoff events.

    PubMed

    Gaertner, James P; Garres, Tiffany; Becker, Jesse C; Jimenez, Maria L; Forstner, Michael R J; Hahn, Dittmar

    2009-03-01

    Sediments and water from the spring and slough arm of Spring Lake, the pristine headwaters of the San Marcos River, Texas, were analyzed for Salmonellae by culture and molecular techniques before and after three major precipitation events, each with intermediate dry periods. Polymerase chain reaction (PCR)-assisted analyses of enrichment cultures detected Salmonellae in samples after all three precipitation events, but failed to detect them immediately prior to the rainfall events. Detection among individual locations differed with respect to the precipitation event analyzed, and strains isolated were highly variable with respect to serovars. These results demonstrate that rainwater associated effects, most likely surface runoff, provide an avenue for short-term pollution of aquatic systems with Salmonellae that do not, however, appear to establish for the long-term in water nor sediments. PMID:18957780

  20. [Regulating the internet: a comparative analysis of Brazil, Chile, Spain, the US, and France].

    PubMed

    Segurado, Rosemary; Lima, Carolina Silva Mandú de; Ameni, Cauê S

    2015-12-01

    Global governance is of key concern in the current debate over the workings of the world's computer network, and Brazil has played a notable role in this process, especially after approval of the Marco Civil da Internet (law 12.965, april 23, 2014), which defines Brazil's regulatory framework for the internet. Dubbed the internet bill of rights, this law sets out the principles, guarantees, rights, and duties of internet users and providers in Brazil. Based on the fundamental categories of net neutrality, internet users' right to privacy, and copyright discussions from the perspective of intellectual property, the article offers a comparative analysis of regulations in five countries: Brazil, Chile, Spain, the US, and France. PMID:25119248

  1. [Industrial nursing. Functions within the basic health unit].

    PubMed

    Aguilera, Antonio Javier Cortés

    2005-02-01

    The Law of Prevention of Risks at Work marked an important point of flexion in the tie sanitary professions the field of the labor health. This work will mark the objective to locate to the Industrial Nursing (a company nursing assistant) in a context near the reality. For it, it will be equipped with legal content, and those articles of the Law of Prevention of Risks at Work will be mentioned and of the Regulations for Prevention Services, that establishes the guidelines of performance of the professionals of the Basic Unit of Health (Industrial Medicina and the company nursing assistant) Also will mention the objectives of the First draft of Law of the Reformation of Normative Marco of the Law of Prevention of Risks at Work, consequence of the alarming data of sinisterness and labor accidental. PMID:15816220

  2. Entropy of Isolated Quantum Systems after a Quench

    NASA Astrophysics Data System (ADS)

    Rigol, Marcos; Santos, Lea; Polkovnikov, Anatoli

    2012-02-01

    A diagonal entropy, which depends only on the diagonal elements of the system's density matrix in the energy representation, has been argued to be the proper definition of thermodynamic entropy in out-of-equilibrium quantum systems. We study this quantity after an interaction quench in lattice hardcore bosons and spinless fermions, and after a local chemical potential quench in a system of hard-core bosons in a superlattice potential. The former systems have a chaotic regime, where the diagonal entropy approaches the equilibrium microcanonical entropy, coinciding with the onset of thermalization. The latter system is integrable. We show that its diagonal entropy is additive and different from the entropy of a generalized Gibbs ensemble, which has been introduced to account for the effects of conserved quantities at integrability [1]. [4pt] [1] Lea F. Santos, Anatoli Polkovnikov, and Marcos Rigol, Phys. Rev. Lett. 107, 040601 (2011).

  3. Origin of arches in the northwestern Gulf of Mexico basin

    SciTech Connect

    Laubach, S.E.; Jackson, M.L.W. )

    1990-07-01

    The San Marcos and Sabine arches are prominent north- to northwest-trending basement uplifts in the northwestern Gulf of Mexico basin that may be late Mesozoic to Cenozoic foreland or intraplate folds rather than domes over plutons or buoyant basement blocks. These arches are subparallel to and contemporaneous with orogenic episodes in the northwest-trending fold-thrust belt of Mexico. Arch movement was also contemporaneous with rapid convergence between the North American and Pacific plates. Arch development in the gulf as a result of tectonic compression is plausible in view of increasing recognition of wide zones of foreland and intraplate deformation in continents. Current tectonic models of the development of the gulf inaccurately predict gradual, decelerating subsidence when these arches were most active.

  4. Interplay between the spin transfer and spin orbit torques on domain walls at the 5d/3d-alloy interfaces

    NASA Astrophysics Data System (ADS)

    Kalitsov, Alan; Okatov, Sergey; Zarzhitsky, Pavel; Chshiev, Mairbek; Velev, Julian; Butler, William; Mryasov, Oleg

    2014-03-01

    The manipulations of domain wall (DW) in thin ferromagnetic layers by current and the spin-orbit coupling (SOC) have attracted significant interest. We report two band model calculations of the spin torque (ST) and the spin current (SC) at 5d/3d interfaces with head-to-head, Bloch and Neel DWs. These calculations are based on the non-equilibrium Green Function formalism and the tight binding Hamiltonian including the s-d exchange interactions and the Rashba SOC parameterized on the basis of ab-initio calculations for Fe/W, FeCo/Ta and Co/Pt interfaces. We find that SOC significantly modifies the ST and violates relations between the spin transfer torque and the divergence of the spin current. This work was supported in part by a Semiconductor Research Corporation program, sponsored by MARCO and DARPA.

  5. Sources of disorder in double-gated graphene-insulator-graphene tunneling devices

    NASA Astrophysics Data System (ADS)

    de La Barrera, Sergio; Roy, Tania; Feenstra, Randall; Vogel, Eric

    2014-03-01

    We demonstrate vertical tunneling through layered graphene / hexagonal boron nitride / graphene heterostructures and investigate the resulting non-linear current-voltage characteristics and gated operation of this device. Some devices show negative differential resistance and steep switching due to a novel resonant tunneling mechanism caused by the graphene density of states, while other devices lack this intriguing feature. We explain the differences in experimental findings by modeling the dominant forms of disorder that can occur in these devices. While certain aspects of current experimental results can be explained in terms of finite-size effects and charge impurities in the surrounding materials and substrate, it is evident that additional forms of disorder remain to be understood. This work was supported by STARnet, a Semiconductor Research Corporation program, sponsored by MARCO and DARPA.

  6. Song of the Dunes as a Self-Synchronized Instrument

    NASA Astrophysics Data System (ADS)

    Douady, S.; Manning, A.; Hersen, P.; Elbelrhiti, H.; Protière, S.; Daerr, A.; Kabbachi, B.

    2006-07-01

    Since Marco Polo it has been known that some sand dunes have the peculiar ability to emit a loud sound with a well-defined frequency, sometimes for several minutes. The origin of this sustained sound has remained mysterious, partly because of its rarity in nature. It has been recognized that the sound is not due to the air flow around the dunes but to the motion of an avalanche, and not to an acoustic excitation of the grains but to their relative motion. By comparing singing dunes around the world and two controlled experiments, in the laboratory and the field, we prove that the frequency of the sound is the frequency of the relative motion of the sand grains. Sound is produced because moving grains synchronize their motions. The laboratory experiment shows that the dune is not needed for sound emission. A velocity threshold for sound emission is found in both experiments, and an interpretation is proposed.

  7. One- and three-dimensional impact-induced tensional failure in rock

    NASA Technical Reports Server (NTRS)

    Ahrens, Thomas J.; Rubin, Allan M.

    1991-01-01

    Planar impact (10 to 25 m/sec) experiments were employed to induce dynamic tensile failure in Bedford limestone for stress durations of 0.5 and 1.3 microsec. Ultrasonic P- and S-wave velocities of recovered targets demonstrate deficits caused by microcracks at tensile stresses greater than 35 and 60 MPa in 1.3 and 0.5 microsec experiments. Three-dimensional impact experiments on 20 cm-sized blocks of Bedford limestone and San Marcos gabbro demonstrate compressional wave velocity deficits up to 30 percent in the vicinity of the crater. The damage microcrack decreases as r exp -1.56 from the crater, indicating a dependence on the magnitude and duration of the tensile hoop stresses associated with the impact-induced shock wave.

  8. Landing Strategies for Small Bodies Missions. - Philae and beyond

    NASA Astrophysics Data System (ADS)

    Ulamec, Stephan

    The investigation of small bodies, comets and asteroids, can contribute substantially to our understanding of the formation and history of the Solar System. In situ observations by Landers play a prominent role in this field. The Rosetta Lander - Philae - is currently on its way to comet Churyumov Gerasimenko. It will land in November 2014 and perform numerous experiments with a set of ten scientific instruments. Philae has been designed, to cope with a wide range of possible comet properties. The considerations taken during its development are relevant for future lander missions to small bodies in the Solar System. Various such missions are currently studied (e.g. Marco Polo or Don Quixote) We will address the mission options and compare applicable technologies with the solutions, chosen for Philae.

  9. [The unicorn and the unicorn horn among apothecaries and physicians].

    PubMed

    Fischer, Louis-Paul; Cossu Ferra Fischer, Véronique

    2011-01-01

    In the 4th century A.D. the first unicorn was shown as a little horse with a twisted horn and was completely different from the Oriental one described by Marco Polo. The new unicorn appeared during the 4th century A.D. in Alexandria. This animal enamoured of purity was used as a Christian symbol of purity and sacrifice and adornment of churches like in Lyons in the 13th century. In the 15th & 17th centuries the unicorn was found again in famous tapestries like La Dame B la Licorne as it meant courage, speed and purity. Since the 6th century the powder of unicorn horn was used as a medicine or a drug against poisoning. Depictions of unicorn can be found in chemist's signs, engravings or paintings until the 19th century. PMID:22073757

  10. Fossil Meteorite Unearthed From Crater

    NASA Astrophysics Data System (ADS)

    Martel, L. M. V.

    2006-06-01

    A team of scientists lead by Wolf Maier (University of Quebec, Canada and University of Pretoria, South Africa and soon at University of Western Australia, Perth) and Marco Andreoli (University of the Witwatersrand and South African Nuclear Energy Corp.) and colleagues who also hail from Canada, South Africa, the United Kingdom, and the United States, have announced the discovery of a 25-centimeter-wide chondritic meteorite unearthed from the 145-million-year-old Morokweng impact crater in South Africa. Found within the crater's impact melt sheet about 770 meters (half a mile) down a drilling borehole, the hefty meteorite's existence would seem improbable given its low chance of surviving the high shock pressures and temperatures normally associated with large impact events. Its unusual composition could mean it is a sample from a previously unknown part of the LL chondrite parent body or maybe it is from an entirely different asteroid population than other known meteorites.

  11. Swimming of bacteria under dielectrophoresis

    NASA Astrophysics Data System (ADS)

    Tran, Ngoc Phu; Marcos, Marcos

    In this work, we present a model to predict the response of a swimming helically flagellated bacterium to a unidirectional dielectrophoretic (DEP) force with its strength varying linearly in space. We employ resistive force theory to compute the hydrodynamic force on the flagellar bundle, and the effects of DEP force and rotational diffusion are examined using the Fokker-Planck equation. The DEP force greatly contributes to the reorientation of the bacterium such that the bacterium's primary axis is aligned with the direction of the force. Interestingly, when the DEP strength varies perpendicularly to the direction of the force, the bacterium's primary axis is no longer aligned with the DEP force, which results in a translation of the bacterium perpendicular to its primary axis. Finally, we show the feasibility to utilize this phenomenon to achieve bacterial focusing. The full name of the second author is MARCOS.

  12. Analisis del contenido curricular de los Documentos Normativos del Programa de Ciencias en el area de biologia para la escuela superior del sistema de educacion publica de Puerto Rico: 1993-2012

    NASA Astrophysics Data System (ADS)

    Davila Montanez, Melissa

    Esta investigacion de naturaleza cualitativa se ocupo de realizar un analisis de contenido documental de los Documentos Normativos del Programa de Ciencias en el area de biologia de la escuela superior del sistema de educacion publica de Puerto Rico del periodo 1993-2012. Los documentos analizados fueron: Guia Curricular, 1995; Marco Curricular, 2003; Estandares de Excelencia, 1996, 2000 y Estandares de Contenido y Expectativas de Grado, 2007. Se indago si hubo cambios en significados en los Componentes Estructurales: Naturaleza de la ciencia, Paradigmas para la ensenanza de la ciencia, Funcion del curriculo formal, Mision de la ensenanza de la ciencia; Contenidos, destrezas y competencias, Estrategias de ensenanza y Evaluacion/Assessment del aprendizaje. El analisis sugiere que no hubo cambios sustanciales en los significados de los Componentes Estructurales. Los documentos estudiados muestran mayormente caracteristicas similares, aunque los documentos mas recientes eran mas descriptivos, explicativos y especificos.

  13. Regiones de formación de la línea de He II λ 1640 en una atmósfera en expansión

    NASA Astrophysics Data System (ADS)

    Venero, R.; Cidale, L.; Ringuelet, A.

    Se calculan perfiles de la línea del He II λ1640 empleando un modelo de atmósfera en expansión con una estructura cromosférica para determinar la región de formación de la línea. El problema se trata en geometría esférica, fuera de equilibrio termodinámico. La ecuación de transporte radiativo se resuelve rigurosamente en el marco de referencia del fluído para distintas leyes de velocidad, monótonamente crecientes, y diferentes leyes de temperatura. Se buscan relaciones globales entre las características del perfil y los parámetros físicos atribuídos a la atmósfera estelar, con la finalidad de definir una herramienta de diagnóstico de las propiedades del medio.

  14. IBA-Europhysics Prize in Applied Nuclear Science and Nuclear Methods in Medicine

    NASA Astrophysics Data System (ADS)

    MacGregor, I. J. Douglas

    2014-03-01

    The Nuclear Physics Board of the European Physical Society is pleased to announce that the 2013 IBA-Europhysics Prize in Applied Nuclear Science and Nuclear Methods in Medicine is awarded to Prof. Marco Durante, Director of the Biophysics Department at GSI Helmholtz Center (Darmstadt, Germany); Professor at the Technical University of Darmstadt (Germany) and Adjunct Professor at the Temple University, Philadelphia, USA. The prize was presented in the closing Session of the INPC 2013 conference by Mr. Thomas Servais, R&D Manager for Accelerator Development at the IBA group, who sponsor the IBA Europhysics Prize. The Prize Diploma was presented by Dr. I J Douglas MacGregor, Chair-elect of the EPS Nuclear Physics Division and Chair of the IBA Prize committee.

  15. Characterization of hourly NOx atmospheric concentrations near the Venice International Airport with additive semi-parametric statistical models

    NASA Astrophysics Data System (ADS)

    Valotto, Gabrio; Varin, Cristiano

    2016-01-01

    An additive modeling approach is employed to provide a statistical description of hourly variation in concentrations of NOx measured in proximity of the Venice "Marco Polo" International Airport, Italy. Differently from several previous studies on airport emissions based on daily time series, the paper analyzes hourly data because variations of NOx concentrations during the day are informative about the prevailing emission source. The statistical analysis is carried out using a one-year time series. Confounder effects due to seasonality, meteorology and airport traffic volume are accounted for by suitable covariates. Four different model specifications of increasing complexity are considered. The model with the aircraft source expressed as the NOx emitted near the airport is found to have the best predictive quality. Although the aircraft source is statistically significant, the comparison of model-based predictions suggests that the relative impact of aircraft emissions to ambient NOx concentrations is limited and the road traffic is the likely dominant source near the sampling point.

  16. Impact of point defects on III-nitride tunnel devices

    NASA Astrophysics Data System (ADS)

    Wickramaratne, Darshana; Lyons, John; van de Walle, Chris G.

    Heterostructures using GaN and InGaN are being pursued in designs of tunnel field-effect-transistors (TFETs) to enable low-power switching devices. Point defects and impurities in these heterostructures can adversely affect the performance of these devices through Shockley-Read-Hall (SRH) and Trap-Assisted-Tunneling (TAT) processes. Using first-principles calculations based on a hybrid functional, we calculate the thermodynamic and charge-state switching levels as well as nonradiative recombination rates of point defects and impurities in GaN and InGaN. Gallium vacancies and their complexes, in particular, are found to be potentially detrimental centers. We then investigate how these defects can contribute to SRH and TAT processes in a nitride TFET device. This work was supported by the Center for Low Energy Systems Technology (LEAST), one of the six SRC STARnet Centers, sponsored by MARCO and DARPA.

  17. Identifying Close Binary Central Stars of PN From the Kepler K2 Mission

    NASA Astrophysics Data System (ADS)

    Jacoby, George H.; Long, Joseph; Kronberger, Matthias; De Marco, Orsola; Hillwig, Todd C.

    2016-01-01

    During the Kepler mission, De Marco et al (2015) reported observing 5 PN central stars. Of these, the light curves for 4 central stars exhibited signatures of close binary interactions during their evolution. While suggestive that a large fraction of PN evolve as a binary phenomenon, the sample is far too small to be compelling. We have acquired Kepler K2 data for campaigns 0 and 2 to monitor an additional 6 central stars, and we expect data for another 8-10 targets in campaign 7. We present preliminary results from Kepler K2 campaigns 0 and 2, describe our expectations for campaign 7, and discuss the challenges of using Kepler for these observations.

  18. PREFACE: DISCRETE 2012 - Third Symposium on Prospects in the Physics of Discrete Symmetries

    NASA Astrophysics Data System (ADS)

    Branco, G. C.; Emmanuel-Costa, D.; González Felipe, R.; Joaquim, F. R.; Lavoura, L.; Palomares-Ruiz, S.; Rebelo, M. N.; Romão, J. C.; Silva, J. P.

    2013-07-01

    The Third Symposium on Prospects in the Physics of Discrete Symmetries (DISCRETE 2012) was held at Instituto Superior Técnico, Portugal, from 3-7 December 2012 and was organised by Centro de Física Teórica de Partículas (CFTP) of Instituto Superior Técnico, Universidade Técnica de Lisboa. This is the sequel to the Symposia that was successfully organised in Valéncia in 2008 and in Rome in 2010. The topics covered included: T, C, P, CP symmetries CPT symmetry, decoherence, Lorentz symmetry breaking Discrete symmetries and models of flavour mixing Baryogenesis, leptogenesis Neutrino physics Electroweak symmetry breaking and physics beyond the Standard Model Accidental symmetries (B, L conservation) Experimental prospects at LHC Dark matter searches Super flavour factories, and other new experimental facilities The Symposium was organised in plenary sessions with a total of 24 invited talks, and parallel sessions with a total of 70 talks, including both invited and selected contributions from the submitted abstracts. The speakers of the plenary sessions were: Ignatios Antoniadis, Abdelhak Djouadi, Rabindra Mohapatra, André Rubbia, Alexei Yu Smirnov, José Bernabéu, Marco Cirelli, Apostolos Pilaftsis, Antonio Di Domenico, Robertus Potting, João Varela, Frank Rathmann, Michele Gallinaro, Dumitru Ghilencea, Neville Harnew, John Walsh, Patrícia Conde Muíño, Juan Aguilar-Saavedra, Nick Mavromatos, Ulrich Nierste, Ferruccio Feruglio, Vasiliki Mitsou, Masanori Yamauchi, and Marcello Giorgi. The Symposium was attended by about 140 participants. Among the social events, there was a social dinner in the historical Associação Comercial de Lisboa, which included a musical performance of 'Fado', the traditional music from Lisbon. The next symposium of the series will be organised by King's College, London University, UK, from 1-5 December 2014. Guest Editors G C Branco, D Emmanuel-Costa, R González Felipe, F R Joaquim, L Lavoura, S Palomares-Ruiz, M N Rebelo, J C Romão, J P Silva and J I Silva-Marcos International Advisory CommitteeLocal Organising Committee Francisco del Águila (Granada)From CFTP Jose Bernabéu (Valencia) Francisco Botella (Valencia)G C Branco Andrzej Buras (Munich)D Emmanuel-Costa Marcos Cerrada (Madrid)R González Felipe Pierluigi Campana (CERN)F R Joaquim Antonio Di Domenico (Rome)L Lavoura John Ellis (CERN)S Palomares-Ruiz Fernando Ferroni (Rome)M N Rebelo Luis Garrido (Barcelona)J C Romão Marcello Giorgi (Pisa)J P Silva Neville Harnew (Oxford)J I Silva-Marcos Maria José Herrero (Madrid) David Hitlin (Caltech)From LIP Gino Isidori (Frascati) Guido Martinelli (Rome)G Barreira Antonio Masiero (Padua)J Varela Nickolaos Mavromatos (London) Vasiliki Mitsou (Valencia) Hitoshi Murayama (Berkeley) Tatsuya Nakada (Lausanne) Antonio Pich (Valencia) Apostolos Pilaftsis (Manchester) Stefan Pokorski (Warsaw) Fabio Zwirner (Padua) Secretariat Dulce Conceição Sandra Oliveira Cláudia Romão discrete2012@cftp.ist.utl.pt http://indico.cern.ch/event/discrete2012 Sponsors CFTP - Centro de Física Teórica de Partículas LIP - Laboratório de Instrumentação e Física Experimental de Partículas IST - Instituto Superior Técnico FCT - Fundação para a Ciência e a Tecnologia Group picture The PDF also contains the conference poster and a list of participants.

  19. Some properties of an infinite family of deformations of the harmonic oscillator

    SciTech Connect

    Quesne, Christiane

    2010-12-23

    In memory of Marcos Moshinsky, who promoted the algebraic study of the harmonic oscillator, some results recently obtained on an infinite family of deformations of such a system are reviewed. This set, which was introduced by Tremblay, Turbiner, and Winternitz, consists in some Hamiltonians H{sub k} on the plane, depending on a positive real parameter k. Two algebraic extensions of H{sub k} are described. The first one, based on the elements of the dihedral group D{sub 2k} and a Dunkl operator formalism, provides a convenient tool to prove the superintegrability of H{sub k} for odd integer k. The second one, employing two pairs of fermionic operators, leads to a supersymmetric extension of H{sub k} of the same kind as the familiar Freedman and Mende super-Calogero model. Some connection between both extensions is also outlined.

  20. [Prominent personalities from the tropical dermatology field in Peru].

    PubMed

    Burstein Alva, Zuño

    2014-01-01

    This article pays tribute to three Peruvian medical personalities: José Neyra Ramirez (1929-2012), Abelardo Tejada (1931-2013) and Oscar Romero Rivas (1929-2011), highlighting their valuable contributions to the field of Tropical Dermatology and Health Medicine that benefited public health and Peruvian medical education. The article mentions the formation of a group of young researchers called “The Anacoretas”, including professors Hugo Pesce, Enrique Encinas, Juan Francisco Valegas in Lima; and Enerst Nausk and Victor Manchego in Germany, who, with the support of the Peruvian and German governments promoted and created the first university research center of Tropical Medicine on the Pacific Coast of Latin America called Daniel A. Carrion Tropical Medicine Institute at Universidad Nacional Mayor de San Marcos in Lima (TMI/UNMSM). PMID:25597737

  1. International Program and Local Organizing Committees

    NASA Astrophysics Data System (ADS)

    2012-12-01

    International Program Committee Dionisio Bermejo (Spain) Roman Ciurylo (Poland) Elisabeth Dalimier (France) Alexander Devdariani (Russia) Milan S Dimitrijevic (Serbia) Robert Gamache (USA) Marco A Gigosos (Spain) Motoshi Goto (Japan) Magnus Gustafsson (Sweden) Jean-Michel Hartmann (France) Carlos Iglesias (USA) John Kielkopf (USA) John C Lewis (Canada) Valery Lisitsa (Russia) Eugene Oks (USA) Christian G Parigger (USA) Gillian Peach (UK) Adriana Predoi-Cross (Canada) Roland Stamm (Germany) Local Organizing Committee Nikolay G Skvortsov (Chair, St Petersburg State University) Evgenii B Aleksandrov (Ioffe Physico-Technical Institute, St Petersburg) Vadim A Alekseev (Scientific Secretary, St Petersburg State University) Sergey F Boureiko (St.Petersburg State University) Yury N Gnedin (Pulkovo Observatory, St Petersburg) Alexander Z Devdariani (Deputy Chair, St Petersburg State University) Alexander P Kouzov (Deputy Chair, St Petersburg State University) Nikolay A Timofeev (St Petersburg State University)

  2. Coupling constant metamorphosis, the Staeckel transform and superintegrability

    SciTech Connect

    Post, Sarah

    2010-12-23

    This paper is dedicated to the memory of Marcos Moshinsky. In this paper, we discuss the important role that coupling constant metamorphosis (CCM) and the Staeckel transform have played in the analysis of superintegrable systems. We explain the relation between the two and in particular show that they coincide when transforming between second-order superintegrable systems. Unlike in the case of second-order superintegrability, the quantum analog of CCM has only been proven for a subclass of systems with integrals of a specific form. We give the proof and as an application show the mapping of a family of superintegrable deformations of the simple harmonic oscillator to an associated family of superintegrable deformations of the Kepler-Coulomb potential.

  3. Statistical panorama of female physics graduate students for 2000-2010 in Peru

    NASA Astrophysics Data System (ADS)

    Cerón Loayza, María Luisa; Bravo Cabrejos, Jorge Aurelio

    2013-03-01

    We report the results of a statistical study on the number of women entering the undergraduate and master's programs of physics at Universidad Nacional Mayor de San Marcos in Peru. From 2006 through 2010, 13 female students entered the master's degree program but no females graduated with the degree. Considering that Peru is a developing country, a career in physics is not considered an attractive professional choice even for male students because it is thought that there are no work centers to practice this profession. We recommend that the causes preventing female physics students from completing their studies and research work be analyzed, and that strategies be planned to help women complete their academic work. We are considering getting help from the Peruvian Physics Society (SOPERFI) in order to draw more attention for our plan.

  4. Space robotics--DLR's telerobotic concepts, lightweight arms and articulated hands.

    PubMed

    Hirzinger, G; Brunner, B; Landzettel, K; Sporer, N; Butterfass, J; Schedl, M

    2003-01-01

    The paper briefly outlines DLR's experience with real space robot missions (ROTEX and ETS VII). It then discusses forthcoming projects, e.g., free-flying systems in low or geostationary orbit and robot systems around the space station ISS, where the telerobotic system MARCO might represent a common baseline. Finally it describes our efforts in developing a new generation of "mechatronic" ultra-light weight arms with multifingered hands. The third arm generation is operable now (approaching present-day technical limits). In a similar way DLR's four-fingered hand II was a big step towards higher reliability and yet better performance. Artificial robonauts for space are a central goal now for the Europeans as well as for NASA, and the first verification tests of DLR's joint components are supposed to fly already end of 93 on the space station. PMID:12703511

  5. [The unicorn and the unicorn horn among apothecaries and physicians].

    TOXLINE Toxicology Bibliographic Information

    Fischer LP; Cossu Ferra Fischer V

    2011-07-01

    In the 4th century A.D. the first unicorn was shown as a little horse with a twisted horn and was completely different from the Oriental one described by Marco Polo. The new unicorn appeared during the 4th century A.D. in Alexandria. This animal enamoured of purity was used as a Christian symbol of purity and sacrifice and adornment of churches like in Lyons in the 13th century. In the 15th & 17th centuries the unicorn was found again in famous tapestries like La Dame B la Licorne as it meant courage, speed and purity. Since the 6th century the powder of unicorn horn was used as a medicine or a drug against poisoning. Depictions of unicorn can be found in chemist's signs, engravings or paintings until the 19th century.

  6. Impregnation transition in a powder

    NASA Astrophysics Data System (ADS)

    Raux, Pascal; Cockenpot, Heloise; Quere, David; Clanet, Christophe

    2011-11-01

    When an initially dry pile of micrometrical grains comes into contact with a liquid, one can observe different behaviors, function of the wetting properties. If the contact angle with the solid is low, the liquid will invade the pile (impregnation), while for higher contact angles, the grains will stay dry. We present an experimental study of this phenomenon: a dry pile of glass beads is deposed on the liquid surface, and we vary the contact angle of the liquid on the grains. We report a critical contact angle below which impregnation always occurs, and develop a model to explain its value. Different parameters modifying this critical contact angle are also investigated. Collaboration with Marco Ramaioli, Nestle Research Center, Lausanne, Switzerland.

  7. An integrated model supporting histological and biometric responses as predictive biomarkers of fish health status

    NASA Astrophysics Data System (ADS)

    Torres Junior, Audalio Rebelo; Sousa, Débora Batista Pinheiro; Neta, Raimunda Nonata Fortes Carvalho

    2014-10-01

    In this work, an experimental system of histological (branchial lesions) biomarkers and biometric data in catfish (Sciades herzbergii) was modeled. The fish were sampled along known pollution areas (S1) and from environmental protect areas (S2) in São Marcos' Bay, Brazil. Gills were fixed in 10% formalin and usual histological techniques were used in the first gill arch right. The lesions were observed by light microscopy. There were no histopathological changes in animals captured at reference site (S1). However, in the catfish collected in the potentially contaminated area (S2) was observed several branchial lesions, such as lifting of the lamellar epithelium, fusion of some secondary lamellae, hypertrophy of epithelial cells and lamellar aneurysm. The analysis using the biometric data showed significant differences, being highest in fish analyzed in the reference area. This approach revealed spatial differences related with biometric patterns and morphological modifications of catfish.

  8. Space systems technology; Proceedings of the Aerospace Congress and Exposition, Long Beach, CA, October 15-18, 1984

    SciTech Connect

    Not Available

    1984-01-01

    Various papers on space system technology are presented. The topics discussed include: gallium arsenide solar cell vapor phase technology, liquid phase epitaxial GaAs solar cells, the San Marco Mission solar array, autonomous solar arrays for the future, application of viscous and inviscid computation methods for rocket turbopump systems, solar dynamic power for a space station, a two-phase thermal management system for the space station, and the effect of bipropellant thruster contaminant on solar array performance. Also considered are: uprated orbital maneuvering engine, pump-fed satellite delivery stage engine technology, lox/hydrocarbon propellants for space propulsion systems, refurbishment of the Space Shuttle solid rocket motor, NASA's approach to flight confidence, diagnostic needs of the Space Shuttle main engine, reusable rocket engine turbopump condition monitoring, Space Shuttle mission extension capability, advanced launch vehicles, and the Space Shuttle main engine overhaul program.

  9. Inelastic vertical tunneling in graphene-based heterostructures

    NASA Astrophysics Data System (ADS)

    de La Barrera, Sergio; Feenstra, Randall

    2015-03-01

    Lateral momentum conservation of tunneling states in graphene / hexagonal boron nitride / graphene heterostructures causes intriguing resonant behavior and negative differential resistance. We explain this phenomenon in terms of a simple model which includes electrostatic gating, rotational alignment between graphene layers, elastic scattering, and inelastic tunneling effects for both monolayer and bilayer graphene. We highlight recent experimental efforts to observe these effects in fabricated devices and compare with theory to validate our theoretical model. In order to improve future fabrication, we discuss disorder mechanisms, the differences between monolayer and bilayer graphene configurations, and the critical parameters which govern the characteristics of these devices. This work was supported in part by the Center for Low Energy Systems Technology (LEAST), one of the six SRC STARnet Centers, sponsored by MARCO and DARPA.

  10. Control of Spin Wave Band Structure and Propagation in Two-Dimensional Magnonic Crystals

    NASA Astrophysics Data System (ADS)

    Sietsema, Glade; Flatté, Michael E.

    2015-03-01

    We have studied the properties of spin waves in two-dimensional magnonic crystals consisting of a magnetic material arranged in a lattice of cylinders and embedded in a second magnetic material. Dispersion curves, linewidths, and spin wave propagation patterns were obtained from the Landau-Lifshitz-Gilbert equation using the plane wave expansion method. We have examined how these results are affected by various parameters including the shape of the cylinders, the lattice structure, the material properties, and the spin-orbit interaction. Adjusting these values can open or close band gaps and drastically shift the frequency range of the band structure. The spin wave propagation patterns were found to exhibit high directionality dependent on the excitation frequency and can also be modified with the aforementioned parameters. This work was supported in part by DARPA/MESO and by C-SPIN, one of six centers of STARnet, a Semiconductor Research Corporation program, sponsored by MARCO and DARPA.

  11. Reversible Mechanical Switching of Magnetic Interactions in a Molecular Shuttle

    PubMed Central

    Bleve, Valentina; Schäfer, Christian; Franchi, Paola; Silvi, Serena; Mezzina, Elisabetta; Credi, Alberto; Lucarini, Marco

    2015-01-01

    Invited for this months cover are the groups of Professors Marco Lucarini and Alberto Credi at the University of Bologna. The cover picture shows coupled and uncoupled states of a [2]rotaxane incorporating stable nitroxide radical units in both the ring and dumbbell components. Interaction between nitroxide radicals could be switched between noncoupled (three-line electron paramagnetic resonance (EPR) spectrum) and coupled (five-line EPR spectrum) upon deprotonation of the rotaxane NH2+ centers that effects a quantitative displacement of a dibenzocrown macroring to a 4,4’-bipyridinium recognition site. The complete base- and acid-induced switching cycle of the EPR pattern was repeated several times without an appreciable loss of signal, highlighting the reversibility of the process. Hence, this molecular machine is capable of switching on/off magnetic interactions by chemically driven reversible mechanical effects. For more details, see the Communication on p. 18 ff. PMID:25870780

  12. A simulation model of water depth in mangrove basin forests.

    PubMed

    Ritchie, S A

    1990-06-01

    The construction and validation of a model simulating the water depth within mangrove basin forests is described. Rainfall, water table, water depth and tide data collected from a red mangrove basin forest on Marco Island, FL, was used to estimate model parameters. These included the basin spillover height, evapotranspiration-infiltration rate and the functional relationship of water depth change to rainfall, tide and basin spillover. The model was constructed with LOTUS 123 and calibrated from staff gauge water depth records. The model proved accurate and adaptable. Water depths from the model and staff gauge were correlated highly (r = 0.98). Data from an adjacent black mangrove forest featuring complex wet-dry cycling were used to modify the model. After calibration, the model provided an accurate record of water depths at the site (r = 0.89). This model will provide water depths used in a model of Aedes taeniorhynchus population dynamics. PMID:2370528

  13. Fabrication of Nanowire Arrays for Molecular Electronics and Chemical Sensing

    NASA Astrophysics Data System (ADS)

    Johnston-Halperin, Ezekiel; Beckman, R.; Melosh, N.; Luo, Y.; Green, J. E.; Boukai, A.; Heath, J. R.

    2004-03-01

    The recently developed technique of superlattice nanowire pattern transfer (SNAP) allows for the fabrication of arrays of nanowires at wire diameter, regularity, aspect ratio, and pitch that exceeds that of currently available techniques [1]. These arrays have potential applications in the fabrication of ultra-dense nanoscale circuits including FET based logic, molecular memory, and chemical sensing with commensurate constraints on nanowire geometry, conductivity, and chemical reactivity. For example, room temperature transport measurements of semiconducting wires show both Ohmic conductivity as well as a pronounced gating response. This enables the construction of a multiplexer with geometric scaling, effectively bridging the macroscopic and mesoscopic size regimes with a scalable architecture. Similar applications for molecular memory and chemical sensing will also be discussed. This work supported by the DARPA Moletronics Program, the Semiconductor Research Corporation, and MARCO Center funding. [1] N. Melosh, et al., Science 300, 112 (2003).

  14. A noteworthy record of Ornithodoros (Alectorobius) coniceps (Ixodida: Argasidae) from Central Italy.

    PubMed

    Khoury, Cristina; Bianchi, Riccardo; Massa, Antonio Andrea; Severini, Francesco; Di Luca, Marco; Toma, Luciano

    2011-06-01

    The first record of Ornithodoros (Alectorobius) coniceps (Canestrini) was reported for Italy in 1877, inside the interstices of the ancient mosaics at S. Marco Basilica in Venice. Afterwards only few discoveries of the species are reported for Italy; the last record is dated back to 1984, in L'Aquila town (Abruzzo Region). The present study shows the data of a survey carried out as a result of a massive infestation by O. coniceps in an ancient villa in Anzio town (Latium region) recently restored. In the past decades the villa has been fallen into disrepair, becoming an occasional shelter for wild animals mainly pigeons, that colonized the whole building for generations. This case appears worthy of note because it is the first record of this species after more than 25 years in Italy. A total of 136 specimens were collected by three methods: manual, mechanical aspirators and Wilson traps. Wilson trapping indicates positive O. coniceps tropism for CO(2). PMID:21298470

  15. Design and testing of a mesoscale actuator device (MAD)

    NASA Astrophysics Data System (ADS)

    Park, Joon; Mitrovic, Milan; Carman, Gregory P.; Hahn, H. Thomas

    2000-06-01

    Three different piezoelectric stacks (PI, NEC, and Marco stack) were characterized in this paper. Their mechanical and electrical properties were first evaluated including Young' modulus, piezoelectric constants, and effective permittivity under mechanical preloads up to 69 MPa (10 ksi) at 2 MV/m. Test result shows that the PI stack generated the highest strain output (2087 μɛ) under a mechanical preload of 55 MPa (8 ksi) at 2 MV/m. As electric field and frequency increased, piezoelectric stack was heated. Heating is mainly caused by power dissipated due to dielectric loss. The power density of the piezoelectric stack was measured under different frequencies, electric fields, and mechanical loads based on a factorial experimental design. Test results indicate that operational frequency influenced the power density more significantly than other parameters.

  16. Science Signaling Podcast for 12 April 2016: G proteins in auriculo-condylar syndrome.

    PubMed

    Garcia-Marcos, Mikel; VanHook, Annalisa M

    2016-01-01

    This Podcast features an interview with Mikel Garcia-Marcos, author of a Research Article that appears in the 12 April 2016 issue ofScience Signaling, about how mutations in a G protein cause auriculo-condylar syndrome (ACS). ACS is caused by mutations that affect signaling through the endothelin type A receptor (ETAR) and is characterized by craniofacial abnormalities resulting from defects in neural crest development. ETAR is a G protein-coupled receptor (GPCR) that signals primarily through heterotrimeric G proteins containing Gαq/11, but mutations in Gαi3are also associated with ACS. Marivinet al found that ETAR coupled to ACS-associated mutant forms of Gαi3instead of coupling to Gαq/11 These mutant forms of Gαi3lacked enzymatic activity and thus blocked ETAR signaling.Listen to Podcast. PMID:27072654

  17. Acknowledgements

    NASA Astrophysics Data System (ADS)

    2011-02-01

    Ackowledgement logos The organizers of the Young Researchers' Meeting in Rome would like to thank all the scientists who participated in the meetings. We thank the Universities of Roma "Tor Vergata" and "La Sapienza" for hosting the first two editions of the conference, and the Physics and Astronomy Doctoral Schools of "La Sapienza" for sponsoring the 2nd meeting. We are grateful to Prof. Roberto Capuzzo-Dolcetta (Univ. "La Sapienza"), Prof. Enzo Marinari (Univ. "La Sapienza"), Prof. Pasquale Mazzotta (Univ. "Tor Vergata"), Prof. Giancarlo Ruocco (Univ. "La Sapienza"), Sig.ra Fernanda Lupinacci (Univ. "La Sapienza"), Dott. Marco Veneziani (Lessico Intellettuale Europeo-CNR), Dott.sa Rossella Cossu (Istituto per le Applicazioni del Calcolo-CNR) and Dott. Paolo Cabella (University of Rome "Tor Vergata") for logistical and technical support, and useful discussions. Conference photographs

  18. New insights into the Edwards Aquifer—Brackish-water simulation, drought, and the role of uncertainty analysis

    USGS Publications Warehouse

    Foster, Linzy K.; White, Jeremy T.

    2016-01-01

    The Edwards aquifer consists of three water-quality zones. The freshwater zone of the Edwards aquifer is bounded to the south by a zone of brackish water (transition zone) where the aquifer transitions from fresh to saline water. The saline zone is downdip from the transition zone. There is concern that a recurrence of extreme drought, such as the 7-year drought from 1950 through 1956, could cause the transition zone to move toward (encroach upon) the freshwater zone, causing production wells near the transition zone to pump saltier water. There is also concern of drought effects on spring flows from Comal and San Marcos Springs. These concerns were evaluated through the development of a new numerical model of the Edwards aquifer.

  19. Final Scientific EFNUDAT Workshop

    ScienceCinema

    None

    2011-10-06

    The Final Scientific EFNUDAT Workshop - organized by the CERN/EN-STI group on behalf of n_TOF Collaboration - will be held at CERN, Geneva (Switzerland) from 30 August to 2 September 2010 inclusive.EFNUDAT website: http://www.efnudat.euTopics of interest include: Data evaluationCross section measurementsExperimental techniquesUncertainties and covariancesFission propertiesCurrent and future facilities  International Advisory Committee: C. Barreau (CENBG, France)T. Belgya (IKI KFKI, Hungary)E. Gonzalez (CIEMAT, Spain)F. Gunsing (CEA, France)F.-J. Hambsch (IRMM, Belgium)A. Junghans (FZD, Germany)R. Nolte (PTB, Germany)S. Pomp (TSL UU, Sweden) Workshop Organizing Committee: Enrico Chiaveri (Chairman)Marco CalvianiSamuel AndriamonjeEric BerthoumieuxCarlos GuerreroRoberto LositoVasilis Vlachoudis Workshop Assistant: Géraldine Jean

  20. The measurement of mangrove characteristics in southwest Florida using SPOT multispectral data

    NASA Technical Reports Server (NTRS)

    Jensen, John R.; Lin, Hongyue; Yang, Xinghe; Ramsey, Elijah, III; Davis, Bruce A.; Thoemke, Chris W.

    1991-01-01

    An intensive in situ sampling program near Marco Island, Florida during 19-23 October 1988 collected information on mangrove type, maximum canopy height, and percent canopy closure. These data were correlated with selected vegetation index information derived from analysis of SPOT multispectral (XS) data obtained on 21 October 1988. The Normalized Difference (ND) vegetation index information was the most highly correlated index with percent canopy closure (r = 0.91). Percent canopy closure information can be used as a surrogate for mangrove density which is of great value when predicting which parts of the mangrove ecosystem are at greatest risk after an oil spill occurs. Such information is very valuable when constructing oil spill Environmental Sensitivity Index (ESI) Maps for tropical regions of the world.

  1. Abundant members of Scavenger receptors family and their identification, characterization and expression against Vibrio alginolyticus infection in juvenile Larimichthys crocea.

    PubMed

    He, Jianyu; Liu, Huihui; Yang, Jingwen; Dong, Xiangli; Wu, Changwen

    2016-03-01

    Scavenger receptors (SRs) are crucial pattern recognition receptors (PRRs) to defense pathogen infection in fish innate immunity. In this paper, some members in SRs family of Larimichthys crocea were identified, including eight genes in the class A, B, D and F families. (G+C) % of all SRs members held 51%?59%, and these genes were no obvious codon bias by analyzing the distribution of A-, T-, G- and C-ended codons. The order of Enc for all SRs members by sequencing was LycCD68>LycSCARA5>LycSCARB1>LycCD163>LycMARCO>LycSREC1>LycSCARA3>LycSREC2. Moreover, different lengths and numbers of exons and introns led to the diverse mRNAs and respective functional domains or motifs, for example, an optional cysteine-rich (SRCR) domain in LycMARCO and LycSCARA5, an epidermal growth factor (EGF) and EGF-like domain in LycSREC1 and LycSREC2. The sub-cellular localization demonstrated SRs members mainly located in plasma membrane or extracellular matrix. Further, all of the SRs members in L.crocea were almost low expressed in heart, gill and intestine, whereas high in spleen and liver. After stimulation by Vibrio alginolyticus, the class A and F families were induced significantly, but the class B and D families expressed less even none after pathogenic infection. All the findings would pave the way to understand not only the evolution of the SR-mediated immune response, but also the complexity of fish immunity. PMID:26876357

  2. Observations of the Generation of Eastward Equatorial Electric Fields Near Dawn

    NASA Technical Reports Server (NTRS)

    Kelley, M. C.; Rodrigues, F. S.; Pfaff, R. F.; Klenzing, J.

    2014-01-01

    We report and discuss interesting observations of the variability of electric fields and ionospheric densities near sunrise in the equatorial ionosphere made by instruments onboard the Communications/Navigation Outage Forecasting System (C/NOFS) satellite over six consecutive orbits. Electric field measurements were made by the Vector Electric Field Instrument (VEFI), and ionospheric plasma densities were measured by Planar Langmuir Probe (PLP). The data were obtained on 17 June 2008, a period of solar minimum conditions. Deep depletions in the equatorial plasma density were observed just before sunrise on three orbits, for which one of these depletions was accompanied by a very large eastward electric field associated with the density depletion, as previously described by de La Beaujardière et al. (2009), Su et al. (2009) and Burke et al. (2009). The origin of this large eastward field (positive upward/meridional drift), which occurred when that component of the field is usually small and westward, is thought to be due to a large-scale Rayleigh-Taylor process. On three subsequent orbits, however, a distinctly different, second type of relationship between the electric field and plasma density near dawn was observed. Enhancements of the eastward electric field were also detected, one of them peaking around 3 mV per meter, but they were found to the east (later local time) of pre-dawn density perturbations. These observations represent sunrise enhancements of vertical drifts accompanied by eastward drifts such as those observed by the San Marco satellite (Aggson et al., 1995). Like the San Marco measurements, the enhancements occurred during winter solstice and low solar flux conditions in the Pacific longitude sector. While the evening equatorial ionosphere is believed to present the most dramatic examples of variability, our observations exemplify that the dawn sector can be highly variable as well.

  3. Geologic Map of the Edwards Aquifer In Northern Medina and Northeastern Uvalde Counties, South-central Texas

    USGS Publications Warehouse

    Clark, Allan K.; Faith, Jason R.; Blome, Charles D.; Pedraza, Diana E.

    2006-01-01

    The southern segment of the Edwards aquifer in south-central Texas is one of the most productive subsurface reservoirs of potable water in the world, providing water of excellent quality to more than a million people in the San Antonio region, where the Environmental Protection Agency (EPA) has declared it to be a sole-source aquifer (van der Leeden and others, 1990). Depending on the depositional province within which the associated carbonate rocks originated (Maclay and Small, 1984), the Edwards aquifer is composed of several geologic formations (primarily limestone and dolostone) of Early Cretaceous age. Most water pumped from the Edwards aquifer comes form the Person and Kainer Formations, which were deposited over the San Marcos Platform. The principal source of ground water in study area is the Devils River Formation, which was deposited in the Devils River trend. The Devils River Formation provides large quantities of irrigation water to fertile bottomland areas of Medina and Uvalde Counties, where the success of farming and ranching activities has long depended upon water from the Edwards aquifer. The study area includes all of the Edwards aquifer recharge zone between the Sabinal River (on the west) and the Medina River (on the east) plus an updip fringe of the confined zone in east-central Uvalde and central Medina Counties. Over about ninety percent of the study area--within the Devils River trend--the Edwards aquifer is composed of the Georgetown Formation plus the underlying Devils River Formation. Over the remaining area--over the southwestern margin of the San Marcos platform--the Edwards aquifer consists of the Georgetown Formation plus the underlying Edwards Group (Rose, 1972), which comprises the Kainer and Person Formations.

  4. Combination of gene expression patterns in whole blood discriminate between tuberculosis infection states

    PubMed Central

    2014-01-01

    Background Genetic factors are involved in susceptibility or protection to tuberculosis (TB). Apart from gene polymorphisms and mutations, changes in levels of gene expression, induced by non-genetic factors, may also determine whether individuals progress to active TB. Methods We analysed the expression level of 45 genes in a total of 47 individuals (23 healthy household contacts and 24 new smear-positive pulmonary TB patients) in Addis Ababa using a dual colour multiplex ligation-dependent probe amplification (dcRT-MLPA) technique to assess gene expression profiles that may be used to distinguish TB cases and their contacts and also latently infected (LTBI) and uninfected household contacts. Results The gene expression level of BLR1, Bcl2, IL4d2, IL7R, FCGR1A, MARCO, MMP9, CCL19, and LTF had significant discriminatory power between sputum smear-positive TB cases and household contacts, with AUCs of 0.84, 0.81, 0.79, 0.79, 0.78, 0.76, 0.75, 0.75 and 0.68 respectively. The combination of Bcl2, BLR1, FCGR1A, IL4d2 and MARCO identified 91.66% of active TB cases and 95.65% of household contacts without active TB. The expression of CCL19, TGFB1, and Foxp3 showed significant difference between LTBI and uninfected contacts, with AUCs of 0.85, 0.82, and 0.75, respectively, whereas the combination of BPI, CCL19, FoxP3, FPR1 and TGFB1 identified 90.9% of QFT- and 91.6% of QFT+ household contacts. Conclusions Expression of single and especially combinations of host genes can accurately differentiate between active TB cases and healthy individuals as well as between LTBI and uninfected contacts. PMID:24885723

  5. Philippine president announces population policy.

    PubMed

    1970-02-01

    President Ferdinand Marcos of the Philippines has announced a national policy for family planning, following his recent reelection for a second term of office. Under the policy adopted by the President, the Philippine Government is committed to undertake and encourage programs to provide information and advice for couples wishing to space or limit their child-bearing activities. The Presidential Commission on Population, in a report based on recommendations drawn up after more than 20 meetings by the 22 members, and states that the unfettered population growth will gravely hamper efforts to improve living standards for Filipinos and will block the attainment of national development goals. However, the Commission emphasized that the program will be educational and persuasive, not coercive. Family planning services have been growing rapidly in the Philippines over the past few years as a result of the initiative of several pioneer organizations assisted by the IPPF. President Marcos' government signed the United Nations Declaration on Population in 1967 and in January 1969 he established The Commission on Population. The Philippine press has consistently backed the campaign for widespread availability of family planning services. The Western Pacific Region of the World Health Organization, under it's Director, Dr. Francisco Dy, which has its headquarters in Manila, has its headquarters in Manila, has fostered a regional interest through its technical discussions and the training of field personnel. Depthnews recently reported that the latest Philippine demographic survey asserts that Filipina women are bearing children so fast that the country will hold on to the undisputed title of possessing the highest birth rate in Asia. The growth rate is 3.5%, and the average completed size of a Filipino family is 6.8 children. This swift rate of growth will boost the 1969 population of 37.1 million to 38.4 at the end of this decade. It is noted that unless curbed, it will double again within 20 years. PMID:12332148

  6. Developmental variation among Cochliomyia macellaria Fabricius (Diptera: Calliphoridae) populations from three ecoregions of Texas, USA.

    PubMed

    Owings, Charity G; Spiegelman, Cliff; Tarone, Aaron M; Tomberlin, Jeffery K

    2014-07-01

    Forensic entomologists rely on published developmental datasets to estimate the age of insects developing on human remains. Currently, these datasets only represent populations of targeted insects from specific locations. However, recent data indicate that populations can exhibit genetic variation in their development, including signatures of local adaptation demonstrated by regionally distinct plastic responses to their environments. In this study, three geographically distinct populations of the secondary screwworm, Cochliomyia macellaria Fabricius (Diptera: Calliphoridae; College Station, Longview, and San Marcos, TX, USA), a common blow fly collected from human remains in the southern USA, were reared in two distinct environments (cool 21 °C, 65 % relative humidity (RH); and warm 31 °C, 70 % RH) over 2 years (2011 and 2012) in order to determine differences in development time and mass. Significant differences in immature and pupal development time, as well as pupal mass, were shown to exist among strains derived from different populations and years. For immature development times, there was evidence of only an environmental effect on phenotype, while genotype by environment interactions was observed in pupal development times and pupal mass. College Station and San Marcos populations exhibited faster pupal development and smaller pupal sizes in the cooler environment relative to the Longview population, but showed an opposite trend in the warm environment. Rank order for College Station and Longview populations was reversed across years. Failure to take genetic variation into consideration when making such estimates can lead to unanticipated error and bias. These results indicate that genetics will have little impact on error when working with Texas genotypes of C. macellaria at ~30 °C and 70 % RH, but will have a more meaningful impact on error in postmortem interval estimates with this species in cooler, drier environments. PMID:24811885

  7. Relational Human Ecology: Reconciling the Boundaries of Humans and Nature

    NASA Astrophysics Data System (ADS)

    McNiel, J.; Lopes, V. L.

    2010-12-01

    Global change is transforming the planet at unprecedented rates. Global warming, massive species extinction, increasing land degradation, overpopulation, poverty and injustice, are all the result of human choices and non-sustainable ways of life. What do we have to do and how much do we have to change to allow a transition to a more ecologically-conscious and just society? While these questions are of central concern, they cannot be fully addressed under the current paradigm, which hinders both our collection of knowledge and derivation of solutions. This paper attempts to develop a new variant of ecological thinking based on a relational ontological/epistemological approach. This is offered as a foundation for the political initiative to strive for a more fulfilling, sustainable and just society. This new approach, theoretically conceptualized as ‘relational human ecology,’ offers a relational (holistic) framework for overcoming mechanistic thinking and exploring questions regarding the long-term attainment of sustainability. Once established, we illustrate how the relational framework offers a new holistic approach centered on participatory inquiry within the context of a community workshop. We conclude with discussing possible directions for future relational human ecological participatory research, conducted from the intersection of myriad participants (i.e. agencies, academics, and community residents), and the ways in which this will allow for the derivation of accurate and sustainable solutions for global change. Key words: relational thinking, human ecology, complex adaptive systems, participatory inquiry, sustainability Vicente L. Lopes (corresponding author) Department of Biology Texas State University San Marcos, TX, USA e-mail: vlopes@txstate.edu Jamie N. McNiel Department of Sociology Texas State University San Marcos, TX, USATable 2 - Comparing Orthodox versus Relational Approaches to Ecological Inquiry * Retroduction, logical reasoning that something must be true because it was known to be true in the past Table 1 - Common Dualisms Prevalent in Western Thinking

  8. International Celestial Reference Frame (ICRF): mantenimiento y extensión

    NASA Astrophysics Data System (ADS)

    Ma, C.; Arias, E. F.; Eubanks, T.; Fey, A. L.; Gontier, A.-M.; Jacobs, C. S.; Sovers, O. J.; Archinal, B. A.; Charlot, P.

    A partir de enero de 1998 el sistema de referencia celeste convencional está representado por el International Celestial Reference System (ICRS) y materializado a través de las coordenadas VLBI del conjunto de radiofuentes extragalácticas que conforman el International Celestial Reference Frame (ICRF). La primera realización del ICRF, fue elaborada en 1995 por un grupo de expertos designado por la IAU, la que encomendó al International Earth Rotation Service el mantenimiento del ICRS, del ICRF y del vínculo con marcos de referencia en otras frecuencias. Una primera extensión del ICRF se realizó entre abril y junio de 1999, con el objetivo primario de proveer posiciones de radiofuentes extragalácticas observadas a partir de julio de 1995 y de mejorar las posiciones de las fuentes ``candidatas" con la inclusión de observaciones adicionales. Objetivos secundarios fueron monitorear a las radiofuentes para verificar que siguen siendo adecuadas para realizar al ICRF y mejorar las técnicas de análisis de datos. Como resultado del nuevo análisis se obtuvo una solución a partir de la cual se construyó la primera extensión del ICRF, denominada ICRF - Ext.1. Ella representa al ICRS, sus fuentes de definición se mantienen con las mismas posiciones y errores que en la primera realización del ICRF; las demás radiofuentes tienen coordenadas mejor determinadas que en ICRF; el marco de referencia se densificó con el agregado de 59 nuevas radiofuentes.

  9. List of Participants

    NASA Astrophysics Data System (ADS)

    2014-07-01

    Alba Paolo (Università di Torino) Becattini Francesco (Università di Firenze) Bombaci Ignazio (Università di Pisa) Bonaccorso Angela (INFN Pisa) Colonna Maria (INFN-LNS Catania) Coraggio Luigi (INFN Napoli) Covello Aldo (Università di Napoli) Di Toro Massimo (Università di Catania) De Angelis Giacomo (INFN-LNL Legnaro) Gargano Angela (INFN Napoli) Gattobigio Mario (INLN, Université de Nice-Sophia Antipolis, CNRS, France) Gensini Paolo (INFN Lecce) Giannini Mauro (Università di Genova) Girlanda Luca (Università del Salento) Giusti Carlotta (Università di Pavia) Greco Vincenzo (Università di Catania) Grossi Eduardo (Università di Firenze) Itaco Nunzio (Università di Napoli) Kievsky Alejandro (INFN Pisa) Lanza Edoardo (INFN Catania) Lavagno Andrea (Politecnico di Torino) Logoteta Domenico (Universidade de Coimbra, Coimbra, Portugal) Lo Iudice Nicola (Università di Napoli) Lombardo Maria Paola (INFN-LNF Frascati) Lo Meo Sergio (ENEA Bologna) Mannarelli Massimo (INFN-LNGS Assergi) Marcucci Laura Elisa (Università di Pisa) Matera Francesco (Università di Firenze) Orlandini Giuseppina (Università di Trento) Pacati Franco (Università di Pavia) Pederiva Francesco (Università di Trento) Pirrone Sara (INFN Catania) Puglisi Armando (Università di Catania) Radici Marco (INFN Pavia) Rinaldi Matteo (Università di Perugia) Roggero Alessandro (Università di Trento) Rolando Valentina (Università di Ferrara) Rosati Sergio (Università di Pisa) Ruggieri Marco (Università di Catania) Salmè Gianni (INFN Roma) Santopinto Elena (INFN Genova) Scopetta Sergio (Università di Perugia) Taiuti Mauro (Università di Genova) Vigezzi Enrico (INFN Milano) Viviani Michele (INFN Pisa) Vorabbi Matteo (Università di Pavia)

  10. Wireless data communication alternatives for small public safety agencies: how one community cost-effectively solved its expanding field data requirements

    NASA Astrophysics Data System (ADS)

    Canning, Ryan M.; Lefebvre, Eric

    2005-06-01

    A growing number of Public Safety agencies have begun leveraging wireless data communication technology to improve tactical response capabilities as well as overall productivity. For years police departments subscribed to CDPD (Cellular Digital Packet Data) services to provide officers with basic dispatch data and criminal database access. Now as cellular carriers have deactivated CDPD and shifted to 2.5G and 3G data services such as 1xRTT, GPRS and EDGE, police departments are scrambling to fill the void. Not surprisingly, the extraordinary investments cellular carriers made to upgrade their infrastructures have been transferred to the customer, with monthly fees running as high as $80 a month per user. It's no wonder public safety agencies have been reluctant to adopt these services. Lost in the fray are those smaller police departments which account for nearly 90% of the nation's total. This group has increasingly sought out alternative data communication solutions that are not predicated on budget-busting monthly access fees. One such example is the Marco Island Police Department (MIPD) in Southwestern Florida that received a Federal grant to augment its existing voice communications with data. After evaluating several different technologies and vendors, MIPD chose a 900 MHz ad hoc mesh network solution based on its ability to provide reliable, high-speed and secure IP-based data communications over extensive distances. This paper will discuss technical details of Marco Island's mobile mesh network implementation; including: coverage area with 900 MHz spread spectrum radios, strategic repeater tower placement, interference, throughput performance, and the necessity for application-persistence software.

  11. In the Footsteps of Roger Revelle: Seagoing Oceanography for Middle School Science

    NASA Astrophysics Data System (ADS)

    Brice, D.; Foley, S.; Knox, R. A.; Mauricio, P.

    2007-12-01

    Now in its fourth year, "In the Footsteps of Roger Revelle" (IFRR) is a middle school science education program that draws student interest, scientific content and coherence with National Science Standards from real-time research at sea in fields of physical science. As a successful collaboration involving Scripps Institution of Oceanography (SIO), Woods Hole Oceanographic Institution (WHOI), National Oceanic and Atmospheric Administration (NOAA), Office of Naval Research (ONR), National Science Foundation (NSF), San Diego County Office of Education (SDCOE), and San Marcos Middle School (SMMS), IFRR brings physical oceanography and related sciences to students at the San Marcos Middle School in real-time from research vessels at sea using SIO's HiSeasNet satellite communication system. With their science teacher on the ship as an education outreach specialist or ashore guiding students in their interactions with selected scientists at sea, students observe shipboard research being carried out live via videoconference, daily e-mails, interviews, digital whiteboard sessions, and web interaction. Students then research, design, develop, deploy, and field-test their own data-collecting physical oceanography instruments in their classroom. The online interactive curriculum encourages active inquiry with intellectually stimulating problem-solving, enabling students to gain critical insight and skill while investigating some of the most provocative questions of our time, and seeing scientists as role- models. Recent science test scores with IFRR students have shown significant increases in classes where this curriculum has been implemented as compared to other classes where the traditional curriculum has been used. IFRR has provided students in the San Diego area with a unique opportunity for learning about oceanographic research, which could inspire students to become oceanographers or at least scientifically literate citizens - a benefit for a country that depends increasingly on technically proficient personnel, and a benefit for society at large.

  12. Orbitrap-based mass analyser for in-situ characterization of asteroids: ILMA, Ion Laser Mass Analyser

    NASA Astrophysics Data System (ADS)

    Briois, C.; Cotti, H.; Thirkell, L.; Space Orbitrap Consortium[K. Aradj, French; Bouabdellah, A.; Boukrara, A.; Carrasco, N.; Chalumeau, G.; Chapelon, O.; Colin, F.; Coll, P.; Engrand, C.; Grand, N.; Kukui, A.; Lebreton, J.-P.; Pennanech, C.; Szopa, C.; Thissen, R.; Vuitton, V.; Zapf], P.; Makarov, A.

    2014-07-01

    Since about a decade the boundaries between comets and carbonaceous asteroids are fading [1,2]. No doubt that the Rosetta mission should bring a new wealth of data on the composition of comets. But as promising as it may look, the mass resolving power of the mass spectrometers onboard (so far the best on a space mission) will only be able to partially account for the diversity of chemical structures present. ILMA (Ion-Laser Mass Analyser) is a new generation high mass resolution LDI-MS (Laser Desorption-Ionization Mass Spectrometer) instrument concept using the Orbitrap technique, which has been developed in the frame of the two Marco Polo & Marco Polo-R proposals to the ESA Cosmic Vision program. Flagged by ESA as an instrument concept of interest for the mission in 2012, it has been under study for a few years in the frame of a Research and Technology (R&T) development programme between 5 French laboratories (LPC2E, IPAG, LATMOS, LISA, CSNSM) [3,4], partly funded by the French Space Agency (CNES). The work is undertaken in close collaboration with the Thermo Fisher Scientific Company, which commercialises Orbitrap-based laboratory instruments. The R&T activities are currently concentrating on the core elements of the Orbitrap analyser that are required to reach a sufficient maturity level for allowing design studies of future space instruments. A prototype is under development at LPC2E and a mass resolution (m/Δm FWHM) of 100,000 as been obtained at m/z = 150 for a background pressure of 10^{-8} mbar. ILMA would be a key instrument to measure the molecular, elemental and isotopic composition of objects such as carbonaceous asteroids, comets, or other bodies devoid of atmosphere such as the surface of an icy satellite, the Moon, or Mercury.

  13. Improving Children’s Menus in Community Restaurants: Best Food for Families, Infants, and Toddlers (Best Food FITS) Intervention, South Central Texas, 2010–2014

    PubMed Central

    Friedman, BJ; Fisher, Deborah Torrey; Biediger-Friedman, Lesli

    2014-01-01

    Background Approximately 32% of US children are overweight or obese. Restaurant and fast food meals contribute 18% of daily calories for children and adolescents aged 2 to 18 years. Changing children’s menus may improve their diets. This case study describes Best Food for Families, Infants, and Toddlers (Best Food FITS), a community-based intervention designed to address childhood obesity. The objective of this study was to improve San Marcos children’s access to healthy diets through partnerships with local restaurants, removing sugar-sweetened beverages, decreasing the number of energy-dense entrées, and increasing fruit and vegetable offerings on restaurant menus. Community Context San Marcos, Texas, the fastest growing US city, has more restaurants and fewer grocery stores than other Texas cities. San Marcos’s population is diverse; 37.8% of residents and 70.3% of children are Hispanic. Overweight and obesity rates among school children exceed 50%; 40.3% of children live below the poverty level. Methods This project received funding from the Texas Department of State Health Services Nutrition, Physical Activity, and Obesity Prevention Program to develop Best Food FITS. The case study consisted of developing a brand, engaging community stakeholders, reviewing existing children’s menus in local restaurants, administering owner–manager surveys, collaborating with restaurants to improve menus, and assessing the process and outcomes of the intervention. Outcome Best Food FITS regularly participated in citywide health events and funded the construction of a teaching kitchen in a new community building where regular nutrition classes are held. Sixteen independent restaurants and 1 chain restaurant implemented new menus. Interpretation Improving menus in restaurants can be a simple step toward changing children’s food habits. The approach taken in this case study can be adapted to other communities. Minimal funding would be needed to facilitate development of promotional items to support brand recognition. PMID:25539127

  14. Temporal analyses of the distribution and diversity of Salmonella in natural biofilms.

    PubMed

    Sha, Qiong; Gunathilake, Anuradha; Forstner, Michael R J; Hahn, Dittmar

    2011-07-01

    The diversity and distribution of salmonellae in freshwater biofilms were analyzed at a fine scale (i.e. in 20 locations from a 324 cm(2) area) for two sites in San Marcos, TX. A concrete storm water overflow channel (City Park) was sampled 4 times and a concrete surface in the spring-fed headwaters of the San Marcos River (Spring Lake) 5 times between April and September 2009, and each biofilm sample analyzed by a combination of traditional enrichment methods and molecular techniques. PCR detection of the invA gene, that encodes a protein of a type III secretion system present in salmonellae, after semi-selective enrichment of salmonellae was achieved in biofilms from all 20 locations at the City Park site, with locations generally being positive 2-3 times out of 4 sampling times for a total of 59% positive samples. InvA gene fragment detection in biofilms was less frequent for the 5 sampling times and 20 locations from the Spring Lake site (18% of all samples), with 1 sampling time being entirely negative and 8 locations remaining negative throughout the study. Rep-PCR fingerprinting of 491 Salmonella isolates obtained from both sites resulted in 30 distinct profiles, with 26 and 7 profiles retrieved from City Park and Spring Lake samples, respectively, and thus with 3 profiles present at both sites, and multiple strains frequently obtained from single locations at both sites. The composition of Salmonella strains in the area analyzed changed in time with large differences between early (April, June) and late sampling times (September) within and among sites, except for one strain (S12) that was present at almost all sampling times at both sites, though often at different locations within the area analyzed. These results demonstrate the presence of salmonellae in natural biofilms and a significant micro-heterogeneity with differences in diversity and persistence of salmonellae. PMID:21536398

  15. BOOK REVIEW: Discrete Symmetries and CP Violation: From Experiment to Theory (Oxford Graduate Texts)

    NASA Astrophysics Data System (ADS)

    Fösel, A.

    2009-03-01

    Discrete Symmetries and CP Violation: From Experiment to Theory by Marco Sozzi discusses C(harge conjugation), P(arity) and T(ime reversal) discrete symmetries and of course CP symmetry in microscopic (atomic, nuclear and particle) physics. It includes a detailed description of key or representative experiments, and major achievements and recent developments are also mentioned. Though lots of excellent textbooks already exist which cover the basics of discrete symmetries and CP violation in theory and experiment, Sozzi has fully achieved the goal of presenting a book that describes the basics of this subject in detail, from an experimental point of view as well as from theory. He also succeeds in finding links between experiments and theory, leading to a better understanding of the subject. Besides, as an experimentalist, discrete symmetries and CP violation appear to the author as ideal subjects to convey the depth and excitement of experimental `beautiful' physics, which Marco S Sozzi - in my opinion - has managed to do brilliantly. Though mainly addressed to graduate students, the book may also be useful to undergraduates (by skipping some of the more advanced sections and utilizing the brief introduction to some topics in the appendices) and to young researchers looking for a wider modern overview of the issues related to CP symmetry. At the end of each chapter, further reading sections are conveniently provided for the reader to find relevant literature for further studies. Problems to solve at the end of each chapter act as 'little tests'. Unfortunately, their solutions are currently absent: perhaps a publication that includes them is planned in the near future. To conclude, the book succeeds in being a complete and self-consistent text describing in up-to-date detail the investigation of discrete symmetries in sub-atomic physics. It also emphasizes the concepts and ingenuity behind many delicate, careful, and by all means 'beautiful' experiments.

  16. STSHV a teleinformatic system for historic seismology in Venezuela

    NASA Astrophysics Data System (ADS)

    Choy, J. E.; Palme, C.; Altez, R.; Aranguren, R.; Guada, C.; Silva, J.

    2013-05-01

    From 1997 on, when the first "Jornadas Venezolanas de Sismicidad Historica" took place, a big interest awoke in Venezuela to organize the available information related to historic earthquakes. At that moment only existed one published historic earthquake catalogue, that from Centeno Grau published the first time in 1949. That catalogue had no references about the sources of information. Other catalogues existed but they were internal reports for the petroleum companies and therefore difficult to access. In 2000 Grases et al reedited the Centeno-Grau catalogue, it ended up in a new, very complete catalogue with all the sources well referenced and updated. The next step to organize historic seismicity data was, from 2004 to 2008, the creation of the STSHV (Sistema de teleinformacion de Sismologia Historica Venezolana, http://sismicidad.hacer.ula.ve ). The idea was to bring together all information about destructive historic earthquakes in Venezuela in one place in the internet so it could be accessed easily by a widespread public. There are two ways to access the system. The first one, selecting an earthquake or a list of earthquakes, and the second one, selecting an information source or a list of sources. For each earthquake there is a summary of general information and additional materials: a list with the source parameters published by different authors, a list with intensities assessed by different authors, a list of information sources, a short text summarizing the historic situation at the time of the earthquake and a list of pictures if available. There are searching facilities for the seismic events and dynamic maps can be created. The information sources are classified in: books, handwritten documents, transcription of handwritten documents, documents published in books, journals and congress memories, newspapers, seismologic catalogues and electronic sources. There are facilities to find specific documents or lists of documents with common characteristics. For each document general information is displayed together with an extract of the information relating to the earthquake. If the complete document was available and no problem with the publishers rights a pdf copy of the document was included. We found this system extremely useful for studying historic earthquakes, as one can access immediately previous research works about an earthquake and it allows to check easily the historic information and so to validate the intensity data. So far, the intensity data have not been completed for earthquakes after 2000. This information would be important for improving calibration of intensity - magnitude calibrations of historic events, and is a work in progress. On the other hand, it is important to mention that "El Catálogo Sismológico Venezolano del siglo XX" (The Seismological Venezuelan Catalog), published in 2012, updates seismic information up to 2007, and that the STSHV was one of its primary sources of information.

  17. Accounting for the Impact of Conservation on Human Well-Being

    PubMed Central

    Milner-Gulland, EJ; Mcgregor, JA; Agarwala, M; Atkinson, G; Bevan, P; Clements, T; Daw, T; Homewood, K; Kumpel, N; Lewis, J; Mourato, S; Palmer Fry, B; Redshaw, M; Rowcliffe, JM; Suon, S; Wallace, G; Washington, H; Wilkie, D

    2014-01-01

    Conservationists are increasingly engaging with the concept of human well-being to improve the design and evaluation of their interventions. Since the convening of the influential Sarkozy Commission in 2009, development researchers have been refining conceptualizations and frameworks to understand and measure human well-being and are starting to converge on a common understanding of how best to do this. In conservation, the term human well-being is in widespread use, but there is a need for guidance on operationalizing it to measure the impacts of conservation interventions on people. We present a framework for understanding human well-being, which could be particularly useful in conservation. The framework includes 3 conditions; meeting needs, pursuing goals, and experiencing a satisfactory quality of life. We outline some of the complexities involved in evaluating the well-being effects of conservation interventions, with the understanding that well-being varies between people and over time and with the priorities of the evaluator. Key challenges for research into the well-being impacts of conservation interventions include the need to build up a collection of case studies so as to draw out generalizable lessons; harness the potential of modern technology to support well-being research; and contextualize evaluations of conservation impacts on well-being spatially and temporally within the wider landscape of social change. Pathways through the smog of confusion around the term well-being exist, and existing frameworks such as the Well-being in Developing Countries approach can help conservationists negotiate the challenges of operationalizing the concept. Conservationists have the opportunity to benefit from the recent flurry of research in the development field so as to carry out more nuanced and locally relevant evaluations of the effects of their interventions on human well-being. Consideración del Impacto de la Conservación sobre el Bienestar Humano Resumen Los conservacionistas cada vez más se comprometen con el concepto del bienestar humano para mejorar el diseño y la evaluación de sus intervenciones. Desde la convención de la influyente Comisión Sarkozy en 2009, los investigadores del desarrollo han estado refinando las conceptualizaciones y los marcos de trabajo para entender y medir el bienestar humano y están comenzando a convergir con un entendimiento común de cuál es la mejor forma de hacer esto. En la conservación el término bienestar humano tiene un uso amplio, pero existe la necesidad de la orientación en su operación para medir los impactos de las intervenciones de la conservación sobre la gente. Presentamos un marco de trabajo para entender el bienestar humano que podría ser útil particularmente en la conservación. El marco de trabajo incluye tres condiciones: cumplir con las necesidades, perseguir objetivos y experimentar una calidad satisfactoria de vida. Resumimos algunas de las complejidades involucradas en la evaluación de los efectos del bienestar de las intervenciones de la conservación con el entendimiento de que el bienestar varía entre la gente, en el tiempo y con las prioridades del evaluador. Los retos clave para la investigación de los impactos del bienestar de las intervenciones de la conservación incluyen la necesidad de crear una colección de estudios de caso para trazar lecciones generalizables: hacer uso del potencial de la tecnología moderna para apoyar la investigación del bienestar; y contextualizar espacial y temporalmente las evaluaciones de los impactos de la conservación sobre el bienestar dentro del marco más amplio del cambio social. Existen caminos que atraviesan la confusión que rodea al término bienestar, y los marcos de trabajo existentes, como el del acercamiento de Bienestar en Países en Desarrollo, pueden ayudar a los conservacionistas a negociar los obstáculos de la operación del concepto. Los conservacionistas tienen la oportunidad de beneficiarse del frenesí reciente de investigación en el campo del desarrollo para así realizar evaluaciones más matizadas y relevantes localmente de los efectos de sus intervenciones sobre el bienestar humano. PMID:24641551

  18. Sky Observation with the Use of the Software Stellarium for Teaching Astronomy in Classes of Youth and Adult Education. (Spanish Title: Observación del Cielo con la Utilización del Software Stellarium en Las Clases de Educación de Jóvenes y Adultos.) Observação do Céu Aliada À Utilização do Software Stellarium no Ensino de Astronomia em Turmas de Educação de Jovens e Adultos (EJA)

    NASA Astrophysics Data System (ADS)

    Oliveira Bernardes, Adriana

    2010-12-01

    The aim of this paper is to present a project developed through a partnership between the Astronomy Club of Itaocara Marcos Pontes (CAIMP) and Jaime de Souza Queiroz College, both located in the town of Itaocara, in the Northwest Fluminense, to disseminate Astronomy in adult education (Education for Youth and Adult). Given the interdisciplinary nature of Astronomy, we have developed this work to motivate the learning of this science by students in adult education, who attend the subjects Chemistry, Physics and Biology. Initially, we conducted a research in the school to assess the prior knowledge of Astronomy class of adult education, noting that there is little knowledge of basic concepts of the discipline. With these data, we were able to elaborate several activities that would enable a greater involvement of students with this science, performing in the school a work of improvement of scientific literacy, whose activities will be presented in this article. El objetivo de este artículo es presentar los resultados de un proyecto realizado por el Club de Astronomía de Itaocara "Marcos Pontes" (CAIMP), conjuntamente con el Colegio Estatal" Jaime de Souza Queiroz", ambos de la ciudad de Itaocara (Noroeste Fluminense - RJ, Brasil), para la difusión de la Astronomía entre los estudiantes, tanto adultos como adolescentes. Teniendo en cuenta la naturaleza interdisciplinaria de la Astronomía, se determinó motivar el estudio de esta ciencia en los estudiantes adultos de nivel secundario matriculados en las asignaturas de Química, Física y Biología. Como primer paso, se investigó el grado de conocimiento sobre astronomía del estudiante. Este estudio inicial mostró niveles de conocimiento muy bajos de los conceptos básicos de esta ciencia, muchos de los cuales deberían haber sido asimilados dentro del plan curricular del curso de Física. Este estudio previo permitió determinar las actividades adecuadas para promover un mayor envolvimiento de los estudiantes en las ciencias, o sea, elaborar y desarrollar un plan de alfabetización científica. Se describe en detalle este plan, las actividades realizadas y los resultados obtenidos hasta el presente. O objetivo do presente artigo é apresentar um projeto desenvolvido através de parceria entre o Clube de Astronomia de Itaocara Marcos Pontes (CAIMP) e o Colégio Estadual Jaime Queiroz de Souza, ambos localizados na cidade de Itaocara, no Noroeste Fluminense, no sentido de divulgar junto às turmas de EJA (Ensino de Jovens e Adultos) a disciplina Astronomia. Conhecendo o caráter interdisciplinar da Astronomia, desenvolvemos este trabalho para motivar o aprendizado de Ciências junto a alunos de EJA do Ensino Médio que cursam as disciplinas Química, Física e Biologia. Inicialmente, realizamos na escola pesquisa sobre o conhecimento prévio de Astronomia da turma de EJA, observando que é escasso o conhecimento de conceitos básicos do tema, muitos dos quais deveriam ser assimilados através do conteúdo da disciplina Física. Com esses dados, foi possível elaborar várias atividades que possibilitassem um maior envolvimento dos estudantes com a Ciência, realizando dentro da escola um trabalho de alfabetização científica, cujas atividades serão apresentadas neste artigo.

  19. Using Geophysics to Define Hydrostratigraphic Units in the Edwards and Trinity Aquifers, Texas

    NASA Astrophysics Data System (ADS)

    Smith, B. D.; Blome, C. D.; Clark, A. K.; Kress, W.; Smith, D. V.

    2007-05-01

    Airborne and ground geophysical surveys conducted in Uvalde, Medina, and northern Bexar counties, Texas, can be used to define and characterize hydrostratigraphic units of the Edwards and Trinity aquifers. Airborne magnetic surveys have defined numerous Cretaceous intrusive stocks and laccoliths, mainly in Uvalde County, that influence local hydrology and perhaps regional ground-water flow paths. Depositional environments in the aquifers can be classified as shallow water platforms (San Marcos Platform, Edwards Group), shoal and reef facies (Devils River Trend, Devils River Formation), and deeper water basins (Maverick Basin, West Nueces, McKnight, and Salmon Peak Formations). Detailed airborne and ground electromagnetic surveys have been conducted over the Edwards aquifer catchment zone (exposed Trinity aquifer rocks), recharge zone (exposed Edwards aquifer rocks), and artesian zone (confined Edwards) in the Seco Creek area (northeast Uvalde and Medina Counties; Devils River Trend). These geophysical survey data have been used to divide the Edwards exposed within the Balcones fault zone into upper and lower hydrostratigraphic units. Although both units are high electrical resistivity, the upper unit has slightly lower resistivity than the lower unit. The Georgetown Formation, at the top of the Edwards Group has a moderate resistivity. The formations that comprise the upper confining units to the Edwards aquifer rocks have varying resistivities. The Eagleford and Del Rio Groups (mainly clays) have very low resistivities and are excellent electrical marker beds in the Seco Creek area. The Buda Limestone is characterized by high resistivities. Moderate resistivities characterize the Austin Group rocks (mainly chalk). The older Trinity aquifer, underlying the Edwards aquifer rocks, is characterized by less limestone (electrically resistive or low conductivity units) and greater quantities of mudstones (electrically conductive or low resistivity units). In the western area (Devils River Trend and Maverick Basin) of the Trinity aquifer system there are well-defined collapse units and features that are marked by moderate resistivities bracketed by resistive limestone and conductive mudstone of the Glen Rose Limestone. In the central part of the aquifer (San Marcos Platform) the Trinity's lithologies are divided into upper and lower units with further subdivisions into hydrostratigraphic units. These hydrostratigraphic units are well mapped by an airborne electromagnetic survey in Bexar County. Electrical properties of the Edwards aquifer also vary across the fresh-saline water interface where ground and borehole electrical surveys have been conducted. The saline- saturated Edwards is predictably more conductive than the fresh-water saturated rocks. Similar fresh-saline water interfaces exist within the upper confining units of the Edwards aquifer (Carrizo-Wilcox aquifer) and the Trinity aquifer rocks.

  20. Stratigraphic reconstruction of two debris avalanche deposits at Colima Volcano (Mexico): Insights into pre-failure conditions and climate influence

    NASA Astrophysics Data System (ADS)

    Roverato, M.; Capra, L.; Sulpizio, R.; Norini, G.

    2011-10-01

    Throughout its history, Colima Volcano has experienced numerous partial edifice collapses with associated emplacement of debris avalanche deposits of contrasting volume, morphology and texture. A detailed stratigraphic study in the south-eastern sector of the volcano allowed the recognition of two debris avalanche deposits, named San Marcos (> 28,000 cal yr BP, V = ~ 1.3 km 3) and Tonila (15,000-16,000 cal yr BP, V = ~ 1 km 3 ). This work sheds light on the pre-failure conditions of the volcano based primarily on a detailed textural study of debris avalanche deposits and their associated pyroclastic and volcaniclastic successions. Furthermore, we show how the climate at the time of the Tonila collapse influenced the failure mechanisms. The > 28,000 cal yr BP San Marcos collapse was promoted by edifice steep flanks and ongoing tectonic and volcanotectonic deformation, and was followed by a magmatic eruption that emplaced pyroclastic flow deposits. In contrast, the Tonila failure occurred just after the Last Glacial Maximum (22,000-18,000 cal BP) and, in addition to the typical debris avalanche textural characteristics (angular to sub-angular clasts, coarse matrix, jigsaw fit) it shows a hybrid facies characterized by debris avalanche blocks embedded in a finer, homogenous and partially cemented matrix, a texture more characteristic of debris flow deposits. The Tonila debris avalanche is directly overlain by a 7-m thick hydromagmatic pyroclastic succession. Massive debris flow deposits, often more than 10 m thick and containing large amounts of tree trunk logs, represent the top unit in the succession. Fluvial deposits also occur throughout all successions; these represent periods of highly localized stream reworking. All these lines of evidence point to the presence of water in the edifice prior to the Tonila failure, suggesting it may have been a weakening factor. The Tonila failure appears to represent an anomalous event related to the particular climatic conditions at the time of the collapse. The presence of extensive water at the onset of deglaciation modified the mobility of the debris avalanche, and led to the formation of a thick sequence of debris flows. The possibility that such a combination of events can occur, and that their probability is likely to increase during the rainy season, should be taken into consideration when evaluating hazards associated with future collapses at Colima volcano.

  1. Micro-facies analyses of late Holocene sediments from the Ein Gedi site (Dead Sea)

    NASA Astrophysics Data System (ADS)

    Neugebauer, I.; Brauer, A.; Schwab, M. J.; Frank, U.; Dulski, P.

    2012-04-01

    Late Holocene Dead Sea sediments of the Ein Gedi profile at the western Dead Sea shore provide high-resolution information about small-scale climatic variations in the Levant. Earlier investigations by Migowski et al. (2004, 2006) demonstrated the high potential of the Ein Gedi site for reconstructing the paleoenvironment of this climate-sensitive region, but also the need for high-resolution analyses. In the study presented here, a multi-proxy approach of micro-facies analyses from thin sections, µXRF element scanning and further magnetic susceptibility measurements allowed detailed analyses of a 2.75m long section from the DSEn composite profile spanning the time from approximately 2 to 4 ka BP. The analysed DSEn sequence of the Dead Sea margin is characterised by a continuous succession of evaporitic varves, composed of alternating detrital and aragonite and/or gypsum layers with intercalated earthquake-induced mixed layers (Marco et al., 1996). In the lower part of the investigated interval a sand deposit is associated to lake-level decline around 3.3 ka BP (Bookman (Ken-Tor) et al., 2004) in the Late Bronze Age. The aim of this study is to establish a detailed high-resolution time series of extreme events and decadal-scale variations in the eastern Mediterranean climate system. Using this data set will further enable determining the influence of the North Atlantic Oscillation and solar irradiation changes on that region. Another objective will be to synchronise the DSEn interval with the new ICDP Dead Sea Deep Drilling Project (DSDDP) cores from the northern deep basin in order to compare sedimentation processes at the Dead Sea shore with those from the deep basin. Bookman (Ken-Tor), R., Enzel, Y., Agnon, A., Stein, M., 2004. Late Holocene lake levels of the Dead Sea. Geological Society of America Bulletin, May/June, 555-571. Marco, S., Stein, M., Agnon, A., 1996. Long-term earthquake clustering: A 50,000-year paleoseismic record in the Dead Sea Graben. Journal of Geophysical Research 101, 6179-6191. Migowski, C., Agnon, A., Bookman, R., Negendank, J.F.W., Stein, M., 2004. Recurrence pattern of Holocene earthquakes along the Dead Sea transform revealed by varve-counting and radiocarbon dating of lacustrine sediments. Earth and Planetary Science Letters 222, 301-314. Migowski, C., Stein, M., Prasad, S., Negendank, J.F.W., 2006. Holocene climate variability and cultural evolution in the Near East. Quaternary Research 66(3), 421-431.

  2. Philippines. Church vs. state: Fidel Ramos and family planning face "Catholic Power".

    PubMed

    1994-08-24

    Catholic groups and individuals united in a public rally in Manila's Rizal Park to decry a "cultural dictatorship," which promotes abortion, homosexuality, lesbianism, sexual perversion, condoms, and artificial contraception. Government spokesmen responded that condoms and contraception were part of government policy to spread family planning knowledge and informed choices among the population. Cardinal Jaime Sin and former president Corazon Aquino joined forces to lead the movement against the national family planning program in the largest demonstration since the ouster of Ferdinand Marcos in 1986. Also criticized was the 85-page draft action plan for the International Conference on Population and Development (ICPD) scheduled for September 1994. Cardinal Sin accused President Clinton of using the action plan to promote worldwide abortion. Under the administration of President Fidel Ramos, family planning funding has quintupled and the number of family planning workers has increased from 200 to 8000. President Ramos has gone the farthest of any administration in opposing the Church's positions on contraception and abortion, although years ago Fidel Ramos and Cardinal Sin were allies in the effort to push out Ferdinand Marcos. The population of the Philippines is 85% Catholic, and laws reflect the Church's doctrine against divorce and abortion. The current growth rate is 2.3%, and the goal is to reduce growth to 2.0% by 1998, the end of Ramos's term in office. The population target is in accord with demographic goals proposed in the UN draft action plan. The Vatican has opposed the language in the plan and may have encouraged other religious leaders to join those opposed to the "war against our babies and children." Sin said that contraceptive distribution was "intrinsically evil" and should be stopped now. Ramos's administration stated that their policies and programs are not "in the hands of the devil" and there is support for the Church on family values and abortion. Health minister Flavier has indicated that illegal abortion has become very common, and control of abortion is through family planning. The Protestant president will oppose abortion at ICDP. PMID:12345705

  3. PREFACE: DISCRETE 2010: Symposium on Prospects in the Physics of Discrete Symmetries

    NASA Astrophysics Data System (ADS)

    Di Domenico, Antonio; Bini, Cesare; Bloise, Caterina; Bossi, Fabio; Faccini, Riccardo; Gauzzi, Paolo; Isidori, Gino; Lipari, Paolo; Ludovici, Lucio; Silvestrini, Luca

    2011-12-01

    The Symposium DISCRETE2010 on Prospects in the Physics of Discrete Symmetries was held at the Sapienza Universitàa di Roma, Italy from 6-11 December 2010. This second edition, after the successful one in Valencia in 2008, covered all theoretical and experimental progress in the field, and aimed at a thorough discussion on the latest developments. The topics covered included: T, C, P, CP symmetries; accidental symmetries (B, L conservation); CPT symmetry, decoherence, Lorentz symmetry breaking; neutrino mass and mixing; cosmology and astroparticles, dark matter searches; experimental prospects at LHC, Super flavor factories, and new facilities. The Symposium was organized in plenary sessions with a total of 23 invited talks, and parallel sessions with a total of 80 talks including both invited and selected contributions from the submitted abstracts. The speakers of the plenary sessions were: Achille Stocchi, Andreas Weiler, Kevin Pitts, Tim Gershon, Marco Sozzi, Neal Weiner, Vasiliki Mitsou, Bernard Sadoulet, Gianfranco Bertone, J. Eric Grove, Mauro Mezzetto, Alexei Yu Smirnov, Oliviero Cremonesi, Antonio Riotto, Reno Mandolesi, Brett Altschul, Jose Bernabeu, Lawrence Hall, Marco Grassi, Yannis K. Semertzidis, Riccardo Barbieri, Gigi Rolandi, Luciano Maiani. The Symposium venue was the CNR (Consiglio Nazionale delle Ricerche) headquarter building, close to the Sapienza University. At the end of the Symposium a special open session, devoted to a wider audience, was held at the Pontifical University of the Holy Cross, in the historical center of Rome. The symposium was attended by about 140 participants, about half coming from Italy, and the rest mainly from other European countries and United States. Among the social events was a concert at the Aula Magna of the Sapienza University, and a social dinner in the historical Palazzo Pallavicini-Rospigliosi on the Quirinale Hill. The next symposium of the series will be organised by IST, Universidade Tàecnica de Lisboa, Portugal, from 3 to 7 December 2012. Roma, November 2011 The Editors Antonio Di Domenico Cesare Bini Caterina Bloise Fabio Bossi Riccardo Faccini Paolo Gauzzi Gino Isidori Paolo Lipari Lucio Ludovici Luca Silvestrini The PDF file also contains committee, secretariat, sponsor and participant lists, plus the conference poster and photograph.

  4. Low-angle slumps in lacustrine environments: the Shoshone (Tecopa basin, California) example

    NASA Astrophysics Data System (ADS)

    Alfaro, Pedro; Gibert, Luis; García Tortosa, Francisco J.; Owen, Geraint; Moretti, Massimo; Scott, Gary

    2015-04-01

    In lacustrine environments, the presence of seismically-induced slump sheets on gentle slopes seems to be very widespread (Alsop and Marco, 2013; García-Tortosa et al., 2011; Gibert et al., 2005). A low-angle slump is extraordinarily well exposed in middle Pleistocene lacustrine deposits of the Tecopa Basin (California, United States), next to the village of Shoshone. Good lateral continuity of stratigraphical sections allowed a detailed description of the slump sheet and a reliable interpretation taking into account main morphological features, data coming from the facies analysis of the involved beds and on the regional tectonic activity. The slump sheet, ~ 2 m thick, is constituted by four units with different rheological characteristics. This heterogeneous composition is the key controlling factor which produces a large variety of soft-sediment deformational structures of different scale (folds, thrusts, breccias, fluidization structures). An earthquake related to regional faults might cause liquefaction and fluidization, and the initiation of the gravitational movement. When slump translation ceases, at the toe of the slump, then contractional strain propagates upslope and internal deformation occurs in the slump sheet. The top bed of the slump sheet, ~1 m of sands, developed decametric-scale folds while underlying sediments migrates laterally from the synform hinges to the core of the anticlines. Different velocity gradients in the downslope direction generate several superposed layer-parallel shear with two main detachments and many secondary internal ones. This new example in the Tecopa Basin, confirms that slumps are a good record of seismicity in low-angle sedimentary environments. Alsop, G.I. & Marco, S. (2013): Seismogenic slump folds formed by gravity-driven tectonics down a negligible subaqueous slope. Tectonophysics, 605: 48-69. García-Tortosa, F.J., Alfaro, P., Gibert, L. & Scott, G (2011): Seismically induced slump on an extremely gentle slope (<1°) of the Pleistocene Tecopa paleolake (California). Geology, 39: 1055-1058. doi:10.1130/G32218.1 Gibert, L., Sanz de Galdeano, C., Alfaro, P., Scott, G. & López Garrido, A.C. (2005): Seismic-induced slump in Early Pleistocene deltaic deposits of the Baza Basin (SE Spain). Sedimentary Geology, 179: 279-294. doi:10.1016/j.sedgeo.2005.06.003.

  5. Multi-Cell High Latitude Density Structure Induced by Ion Drag during Active Periods

    NASA Astrophysics Data System (ADS)

    Walterscheid, R. L.; Crowley, G.

    2012-12-01

    During active periods two-cell convection patterns can produce four-cell density structure in the high-latitude thermosphere. During these periods density perturbations approaching 50% are possible. The occurrence of density structures that are more complex than the forcing itself suggests that the structure is caused by a profound change in the balance of forces. Using a General Circulation Model of the thermosphere, we compare the balance of forces in the upper and lower thermosphere during active and quiet times. We also examine the thermal structure caused by the dynamical adjustment to ion-drag forcing in relation to the other terms as a balanced state is approached. Simulations reveal that where ion drag is unable to accelerate the atmosphere into rapid motion (during quiet times or at low thermospheric altitudes) the Coriolis force is the dominant inertial term, and for fixed pressure levels centers of cyclonic motion are (per the usual meteorology relations) colder and denser than the surrounding air, while centers of anticyclonic motion are warmer and less dense. At fixed heights, densities are high in the evening anticyclonic gyre, and low in the dawn cyclonic gyre. However, this situation is radically changed during active periods when the atmosphere is spun up to rapid motion and the centrifugal force resulting from curved trajectories is the dominant inertial force. When this occurs, the high latitude anticyclones and cyclones both become centers of relatively cold high density air at fixed height. Cold low-density centers are found on both the dawn and dusk sides with a trough of low density air over the pole connecting them. This intrusion of low density splits the evening high density region that exists under quiet conditions giving the four cell pattern found by Crowley et al. [1989; 1996a, b]. Crowley, G., J. Schoendorf, R. G. Roble, F. A. Marcos (1996a). Cellular structures in the high latitude lower thermosphere, J. Geophys. Res. 101, 211-223 Crowley, G., J. Schoendorf, R. G. Roble, F. A. Marcos (1996b). Neutral density cells in the lower thermosphere at high latitudes, Adv. Space Res., 18 (3). 69-74 Crowley, G., D. J. Knipp, K. A. Drake, J. Lei, E. Sutton, and H. Lühr (2010), Thermospheric density enhancements in the dayside cusp region during strong BY conditions, Geophys. Res. Lett., 37, L07110, doi:10.1029/2009GL042143.

  6. Streamflow Conditions in the Guadalupe River Basin, South-Central Texas, Water Years 1987-2006 - An Assessment of Streamflow Gains and Losses and Relative Contribution of Major Springs to Streamflow

    USGS Publications Warehouse

    Ockerman, Darwin J.; Slattery, Richard N.

    2008-01-01

    The U.S. Geological Survey, in cooperation with the Edwards Aquifer Authority, assessed available streamflow data in the Guadalupe River Basin to determine streamflow gains and losses and the relative contribution of flow from major springs - Comal Springs, San Marcos Springs, and Hueco Springs - to streamflow in reaches of the Guadalupe River and its tributaries. The assessment is based primarily on long-term (1987-2006) and short-term (January 1999, August 1999, August 2000, and August 2006) streamflow conditions. For each analysis period, the ratio of flow from the major springs (measured at the spring source) to the sum of inflows (measured at the source of inflow to the river system) is computed for reaches of the Comal River and San Marcos River that include springflows from major springs, and for Guadalupe River reaches downstream from Canyon Dam. The ratio of springflow to the sum of inflows to the reach is an estimate of the contribution of flows from major springs to streamflow. For 1987-2006, the ratio of springflow from the major springs to the sum of inflows for the most upstream reach that includes inflow from all three major springs, Guadalupe River - above Comal River to Gonzales, is 27 percent. At the lowermost downstream reach, Guadalupe River - Bloomington to the San Antonio River, the percentage of the sum of inflows attributed to springflow is 18 percent. At that lowermost reach, the ratio of Canyon Lake releases to the sum of inflows was 20 percent. For the short-term periods August 2000 and August 2006 (periods of relatively low flow), springflow in the reach Guadalupe River - above Comal River to Gonzales accounted for 77 and 78 percent, respectively, of the sum of inflows in that reach. At the lowermost reach Guadalupe River - Bloomington to San Antonio River, springflow was 52 and 53 percent of the sum of inflows, respectively, during August 2000 and August 2006 (compared with 18 percent during 1987-2006); and during August 2000 and August 2006, the ratios of Canyon Lake releases to the sum of inflows were less than 10 percent (compared with 20 percent during 1987-2006)

  7. In the Footsteps of Roger Revelle: A STEM Partnership Between Scripps Institution of Oceanography, Office of Naval Research and Middle School Science Students Bringing Next Generation Science Standards into the Classroom through Ocean Science

    NASA Astrophysics Data System (ADS)

    Brice, D.; Appelgate, B., Jr.; Mauricio, P.

    2014-12-01

    Now in its tenth year, "In the Footsteps of Roger Revelle" (IFRR) is a middle school science education program that draws student interest, scientific content and coherence with Next Generation Science Standards from real-time research at sea in fields of physical science. As a successful collaboration involving Scripps Institution of Oceanography (SIO),Office of Naval Research (ONR), and San Marcos Middle School (SMMS), IFRR brings physical oceanography and related sciences to students at the San Marcos Middle School in real-time from research vessels at sea using SIO's HiSeasNet satellite communication system. With a generous grant from ONR, students are able to tour the SIO Ships and spend a day at sea doing real oceanographic data collection and labs. Through real-time and near-realtime broadcasts and webcasts, students are able to share data with scientists and gain an appreciation for the value of Biogeochemical research in the field as it relates to their classroom studies. Interaction with scientists and researchers as well as crew members gives students insights into not only possible career paths, but the vital importance of cutting edge oceanographic research on our society. With their science teacher on the ship as an education outreach specialist or ashore guiding students in their interactions with selected scientists at sea, students observe shipboard research being carried out live via videoconference, Skype, daily e-mails, interviews, digital whiteboard sessions, and web interaction. Students then research, design, develop, deploy, and field-test their own data-collecting physical oceanography instruments in their classroom. The online interactive curriculum models the Next Generation Science Standards encouraging active inquiry and critical thinking with intellectually stimulating problem- solving, enabling students to gain critical insight and skill while investigating some of the most provocative questions of our time, and seeing scientists as role-models. IFRR has provided students in the San Diego area with a unique opportunity for learning about oceanographic research, which could inspire students to become oceanographers or at least scientifically literate citizens, a benefit for our society at large.

  8. In the Footsteps of Roger Revelle: a Partnership between SIO, ONR and Middle School Science Students

    NASA Astrophysics Data System (ADS)

    Brice, D.; Appelgate, T. B.; Foley, S.; Knox, R. A.; Mauricio, P.

    2010-12-01

    Now in its seventh year, “In the Footsteps of Roger Revelle” (IFRR) is a middle school science education program that draws student interest, scientific content and coherence with National Science Standards from real-time research at sea in fields of physical science. As a successful collaboration involving Scripps Institution of Oceanography (SIO), National Science Foundation (NSF),Office of Naval Research (ONR), and San Marcos Middle School (SMMS), IFRR brings physical oceanography and related sciences to students at the San Marcos Middle School in real-time from research vessels at sea using SIO's HiSeasNet satellite communication system. With a generous grant from ONR, students are able to tour the SIO ships and spend a day at sea doing real oceanographic data collection and labs. Through real-time and near-realtime broadcasts and webcasts, students are able to share data with scientists and gain an appreciation for the value of biogeochemical research in the field as it relates to their classroom studies. The primary impact on these students is an appreciation of ocean science as it relates to their lives. Interaction with scientists and researchers as well as crew members gives students insights into not only possible career paths, but the vital importance of cutting edge oceanographic research on our society. With their science teacher on the ship as an education outreach specialist or ashore guiding students in their interactions with selected scientists at sea, students observe shipboard research being carried out live via videoconference, Skype, daily e-mails, interviews, digital whiteboard sessions, and web interaction. Students then research, design, develop, deploy, and field-test their own data-collecting physical oceanography instruments in their classroom. The online interactive curriculum encourages active inquiry with intellectually stimulating problem- solving, enabling students to gain critical insight and skill while investigating some of the most provocative questions of our time, and seeing scientists as role-models. Over the last seven years science test scores with IFRR students have shown significant increases in classes where this curriculum has been implemented as compared to other classes where the traditional curriculum has been used. IFRR has provided students in the San Diego area with a unique opportunity for learning about oceanographic research, which could inspire students to become oceanographers or at least scientifically literate citizens, a benefit for a country that depends increasingly on technically proficient personnel, and a benefit for society at large.

  9. A Genetic Cluster of Martian Trojan Asteroids

    NASA Astrophysics Data System (ADS)

    Christou, Apostolos

    2013-10-01

    Trojan asteroids lead 60 degrees ahead (L4) or trail 60 degrees behind (L5) a planet's position along its orbit. The Trojans of Jupiter and Neptune are thought to be primordial remnants from the solar system's early evolution (Shoemaker et al., 1989; Sheppard et al., 2006). Mars is the only terrestrial planet known to host stable Trojans (Scholl et al., 2005) with ~50 km-sized objects expected to exist (Tabachnik and Evans, 1999). I identified 6 additional candidate Martian Trojans within the Minor Planet Center database, including three with multi-opposition orbits. 100 dynamical clones for each of the three asteroids were integrated for 100 Myr under a force model that included the Yarkovsky effect. All clones persisted as L5 Trojans of Mars, implying that their residence time is longer still. This is further supported by recent Gyr numerical integrations (de la Fuente Marcos and de la Fuente Marcos, 2013). The number of stable Martian Trojans is thus raised to 7, 6 of which are at L5. To investigate this asymmetry, I apply a clustering test to their orbits and compare them with the Trojan population of Jupiter. I find that, while Jupiter Trojans are spread throughout the domain where long-term stability is expected, L5 martian Trojans are far more concentrated. The implication is that these objects may be genetically related to each other and to the largest member of the group, 5261 Eureka. If so, it represents the closest such group to the Earth's orbit, still recognizable due to the absence of planetary close encounters which quickly scatter NEO families (Schunova et al., 2012). I explore the origin and nature of this `Eureka cluster', including the thesis that its members are products of the collisional fragmentation and/or rotational fission of Trojan progenitors. I constrain the cluster's age under these scenarios and argue that collisions may be responsible for the observed paucity of km-sized objects. Finally, I discuss how the hypothesis of a genetic association may be further scrutinized by new models and observations. Astronomical Research at Armagh Observatory is funded by the Northern Ireland Department of Culture, Arts and Leisure (DCAL).

  10. Apoyo a Estudios Geodinamicos con GPS en Guatemala

    NASA Astrophysics Data System (ADS)

    Robles, V. R.

    2013-05-01

    El Instituto Geografico Nacional de Guatemala implemento 17 estaciones GNSS en el año 2009, como un proyecto de credito mixto de donacion de equipamiento del Gobierno de Suiza, el cual, este equipamiento de estaciones CORS GNSS es un sistema de recepción y transmisión de datos crudos GPS RInex que utiliza la tecnologia Spider Web de Leica, asi mismo este sistema esta sirviendo para el espablecimiento de un marco geodesico nacional de coordenadas geodesicas oficiales, el cual se calculan u obtienen las velocidades en tiempos temporales programados de las 17 Estaciones CORS. La infraestructura del marco geodesico de Guatemala esta sirviendo de base para las aplicaciones de estudios geodinamicos como el monitoreo de del desplazamiento de las placas tectonicas por medio de un estudio que se inicio en el año de 1999, llamado medicion con GPS el sistema de Fallas de los rios Polochic Motagua de Guatemala, tambien para un estudio que se implemento para deformación de corteza terrestre local en un Volcan Activo de Guatemala llamado Pacaya. Para el estudio de medicion con GPS en el sistema de falla de los Rios del polochic Motagua se implementaron 16 puntos para medir con GPS de dos frecuencias en el año de 1999, el cual, tres puntos son estaciones geodesicas CORS IGS llamados GUAT, ELEN y HUEH, despues en el año de 2003 se hizo otra medicion en un total de 20 puntos, que permitió calcular las velocidades de desplazamieinto de los puntos en mención, usando como referencia el modelo NUVEL 1A de DeMets de la placa de Norteamerica. Este estudio fue en cooperación internacional por la universidad de Nice de Francia y el IGNde Francia. Para el estudio del monitoreo con GPS del volcan activo de Guatemala, se implementaron cuatro puntos al rededor del volcan, el cual, se realizan cuatro mediciones al año, que permiten determinar axialmente la distancias entre los puntos, y rebisar estadisticamente cual es el comportamiento de las distancias en funcion del tiempo, si existen diferencias graduales crecientes o decrecientes, que nos da un indicativo del desplazamiento de la corteza terrestre al rededor del volcan.

  11. The Generation of Active Oxygen Species Differs in Tobacco and Grapevine Mesophyll Protoplasts1

    PubMed Central

    Papadakis, Anastasia K.; Roubelakis-Angelakis, Kalliopi A.

    1999-01-01

    Our previous results have shown that oxidative stress may reduce the regeneration potential of protoplasts, but only protoplasts that are able to supply extracellularly H2O2 can actually divide (C.I. Siminis, A.K. Kanellis, K.A. Roubelakis-Angelakis [1993] Physiol Plant 87: 263270; C.I. Siminis, A.K. Kanellis, K.A. Roubelakis-Angelakis [1994] Plant Physiol 1105: 13751383; A. de Marco, K.A. Roubelakis-Angelakis [1996a] Plant Physiol 110: 137145; A. de Marco, K.A. Roubelakis-Angelakis [1996b] J Plant Physiol 149: 109114). In the present study we have attempted to break down the oxidative burst response into the individual active oxygen species (AOS) superoxide (O2?) and H2O2, and into individual AOS-generating systems during the isolation of regenerating tobacco (Nicotiana tabacum L.) and non-regenerating grape (Vitis vinifera L.) mesophyll protoplasts. Wounding leaf tissue or applying purified cellulase did not elicit AOS production. However, the application of non-purified cellulase during maceration induced a burst of O2? and H2O2 accumulation in tobacco leaf, while in grape significantly lower levels of both AOS accumulated. AOS were also generated when protoplasts isolated with purified cellulase were treated with non-purified cellulase. The response was rapid: after 5 min, AOS began to accumulate in the culture medium, with significant quantitative differences between the two species. In tobacco protoplasts and plasma membrane vesicles, two different AOS synthase activities were revealed, one that showed specificity to NADPH and sensitivity to diphenyleneiodonium (DPI) and was responsible for O2? production, and a second NAD(P)H activity that was sensitive to KCN and NaN3, contributing to the production of both AOS. The first activity probably corresponds to a mammalian-like NADPH oxidase and the second to a NAD(P)H oxidase-peroxidase. In grape, only one AOS-generating activity was detected, which corresponded to a NAD(P)H oxidase-peroxidase responsible for the generation of both AOS. PMID:10482675

  12. Alejarse como proceso social: niños y ancianos «abandonados» en Ayacucho1

    PubMed Central

    Leinaweaver, Jessaca

    2013-01-01

    En investigaciones previas sobre el acogimiento familiar y la adopción en Ayacucho, se ha podido descubrir cómo los ayacuchanos adquieren y producen relaciones sociales. Mientras negocian creativamente los discursos y espacios construidos simultáneamente por instituciones, comunidades, y estructuras sociales, van adquiriendo nuevas formas de relacionarse. Este artículo discute el proceso opuesto: el deshacerse de relaciones de parentesco, y el proceso social del abandono o alejamiento. Cuando se aleja a una persona de su familia o su comunidad, los que se quedan en ella llegan a entenderse como ciertos tipos de personas. En los estudios de caso discutidos aquí, recopilados a través de una detallada y cuidadosa observación participante y de entrevistas etnográficas grabadas entre 2001 y 2007, se puede ver cómo, después de un alejamiento social, los individuos que alejan se reinterpretan como sujetos que se encuentran superándose o volviéndose modernos, o bien sacrificándose. PMID:25177044

  13. PubMed

    Litewka, Sergio; Goodman, Kenneth; Braunschweiger, Y Paul

    2008-01-01

    El Programa CITI (Collaborative Institutional Training Initiative) es un curso basado en Internet y desarrollado por voluntarios, que brinda material educacional sobre protección de sujetos humanos en investigaciones biomédicas y de conducta, buenas prácticas clínicas, conducta responsable de la investigación y trato humanitario a animales de laboratorio. Es un esfuerzo conjunto del Fred Hutchinson Cancer Research Center y la Universidad de Miami.Con la colaboración de expertos locales, gran parte del contenido se ha adaptado para América Latina, se ha traducido al español y portugués y se han establecido acuerdos de colaboración con instituciones especializadas en bioética en Chile, Brasil, Costa Rica y Perú. Los autores presentan una metodología accesible para la capacitación en ética de la investigación y una justificación de su uso y difusión en América Latina. PMID:21687817

  14. BIOÉTICA EN NICARAGUA

    PubMed Central

    Gonzálezy, Armando Ulloa; Monge, Melba de la Cruz Barrantes

    2009-01-01

    Este trabajo describe la situación de la bioética en Nicaragua, caracterizando las circunstancias y el contexto de las actividades de educación médica y las unidades prestadoras de servicios de salud. El desarrollo de un nuevo modelo de atención integral en salud, la implementación de políticas de salud que garanticen a la población el mayor acceso y gratuidad a los servicios, y los cambios acontecidos en los cuidados médicos, debidos en parte al reconocimiento creciente de una mayor autonomía de los pacientes y al uso creciente de nuevas tecnologías médicas, hace que se presenten algunas limitantes y dilemas en las unidades asistenciales y entre el personal de salud. La bioética en Nicaragua tiene un desarrollo incipiente: no está institucionalizada ni se han previsto los mecanismos formales que permitan resolver los problemas éticamente complejos, por lo tanto, constituye un gran reto por parte de las instituciones educativas y rectoras de la salud. PMID:20352016

  15. BLAST Observations of Nearby Galaxies

    NASA Astrophysics Data System (ADS)

    Thomas, Nicholas Evan; Ade, P. A. R.; Bock, J. J.; Chapin, E. L.; Devlin, M. J.; Dicker, S.; Griffin, M.; Gundersen, J. O.; Halpern, M.; Hargrave, P. C.; Hughes, D. H.; Klein, J.; Marsden, G.; Martin, P. G.; Mauskopf, P.; Netterfield, C. B.; Olmi, L.; Pascale, E.; Patanchon, G.; Rex, M.; Scott, D.; Semisch, C.; Truch, M. D. P.; Tucker, C.; Tucker, G. S.; Viero, M. P.; Wiebe, D. V.

    2009-01-01

    The Balloon-born Large Aperture Submillimeter Telescope (BLAST) is a 1.8 m mirror that uses focal plane arrays of bolometer detectors at 250, 350 and 500 microns to study the evolutionary history and processes associated with star formation. The most recent long duration balloon flight from Antarctica collected 250 hours of data during a circumpolar flight in December 2006. A large number of observations were conducted including deep and wide surveys to characterize submillimeter galaxies, a galactic plane survey in the Vela region, and a number of pointed observations toward nearby galaxies NGC1097, NGC1291, NGC1365, NGC1512, NGC1566, and NGC1808. In this talk we will focus on these galaxies and combine the BLAST data with Spitzer-MIPS data to uniquely determine dust properties such as temperature and emissivity. The BLAST collaboration acknowledges the support of NASA through grants NAG5 12785, NAG5-13301, and NNGO-6GI11G, the Canadian Space Agency (CSA), the Science and Technology Facilities Council (STFC), Canada's Natural Sciences and Engineering Research Council (NSERC), the Canada Foundation for Innovation, the Ontario Innovation Trust, the Puerto Rico Space Grant Consortium, the Fondo Institucional para la Investigacion of the University of Puerto Rico, and the National Science Foundation Office of Polar Programs.

  16. Biblioteca Virtual de Salud Enfermería Regional: Trayectoria de Construcción, Fuentes de Información, Estrategias y Próximos Pasos.

    PubMed Central

    Lana, Francisco C. F.; Malvárez, Silvina

    2012-01-01

    Resumen La BVS Enfermeria constituye un nuevo paradigma en enfermería una vez que o modelo representa una expansión de la cooperación técnica y ha como objetivos centrales promover la ampliación del acceso la información sobre enfermería la través del acceso universal equitativo y construir un patrimonio informacional en enfermería, ayudando la mejorar la formación y práctica de enfermería a actuar con compromiso ético-social en el área de educación, investigación y atención a la salud. Como resultado del proceso de sensibilización, verifica-se la construcción de Bibliotecas Virtuales de Enfermería en varios países (Brasil, Argentina, Bolívia y Uruguay). La expectativa es que las BVS’s nacionais convergen a un gran portal que se está construyendo en una colaboración con BIREME/OPS/OMS, de la Asesoría Regional de Enfermería de la OPS-Washington y de Ministerio de Salud del Brasil, así como instituciones líderes en la producción del conocimiento en enfermería Iberoamérica. PMID:24199093

  17. EL PROGRAMA CITI: UNA ALTERNATIVA PARA LA CAPACITACIÓN EN ÉTICA DE LA INVESTIGACIÓN EN AMÉRICA LATINA

    PubMed Central

    Litewka, Sergio; Goodman, Kenneth; Braunschweiger, y Paul

    2011-01-01

    El Programa CITI (Collaborative Institutional Training Initiative) es un curso basado en Internet y desarrollado por voluntarios, que brinda material educacional sobre protección de sujetos humanos en investigaciones biomédicas y de conducta, buenas prácticas clínicas, conducta responsable de la investigación y trato humanitario a animales de laboratorio. Es un esfuerzo conjunto del Fred Hutchinson Cancer Research Center y la Universidad de Miami. Con la colaboración de expertos locales, gran parte del contenido se ha adaptado para América Latina, se ha traducido al español y portugués y se han establecido acuerdos de colaboración con instituciones especializadas en bioética en Chile, Brasil, Costa Rica y Perú. Los autores presentan una metodología accesible para la capacitación en ética de la investigación y una justificación de su uso y difusión en América Latina PMID:21687817

  18. Results on three predictions for July 2012 federal elections in Mexico based on past regularities.

    PubMed

    Hernández-Saldaña, H

    2013-01-01

    The Presidential Election in Mexico of July 2012 has been the third time that PREP, Previous Electoral Results Program works. PREP gives voting outcomes based in electoral certificates of each polling station that arrive to capture centers. In previous ones, some statistical regularities had been observed, three of them were selected to make predictions and were published in arXiv:1207.0078 [physics.soc-ph]. Using the database made public in July 2012, two of the predictions were completely fulfilled, while, the third one was measured and confirmed using the database obtained upon request to the electoral authorities. The first two predictions confirmed by actual measures are: (ii) The Partido Revolucionario Institucional, PRI, is a sprinter and has a better performance in polling stations arriving late to capture centers during the process. (iii) Distribution of vote of this party is well described by a smooth function named a Daisy model. A Gamma distribution, but compatible with a Daisy model, fits the distribution as well. The third prediction confirms that errare humanum est, since the error distributions of all the self-consistency variables appeared as a central power law with lateral lobes as in 2000 and 2006 electoral processes. The three measured regularities appeared no matter the political environment. PMID:24386103

  19. Brazilian actions to promote physiology learning and teaching in secondary and high schools.

    PubMed

    Mello-Carpes, Pâmela B; Granjeiro, Érica Maria; Montrezor, Luís Henrique; Rocha, Maria José Alves

    2016-06-01

    Members of the Education Committee of the Brazilian Society of Physiology have developed multiple outreach models to improve the appreciation of science and physiology at the precollege level. The members of this committee act in concert with important Brazilian governmental strategies to promote training of undergraduate students in the teaching environment of secondary and high schools. One of these governmental strategies, the Programa Institucional de Bolsas de Iniciação à Docência, a Brazilian public policy of teaching enhancement implemented by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) since 2007, represents a well-articulated public policy that can promote the partnership between University and Schools (7). Furthermore, the Program "Novos Talentos" (New Talents)/CAPES/Ministry of Education is another government initiative to bring together university and high-level technical training with the reality of Brazilian schools. Linked to the New Talents Program, in partnership with the British Council/Newton Fund, CAPES recently promoted the visit of some university professors that coordinate New Talents projects to formal and informal educational science spaces in the United Kingdom (Science, Technology, Engineering, and Mathematics, Brazil-United Kingdom International Cooperation Program) to qualify the actions developed in this area in Brazil, and one of us had the opportunity to participate with this. PMID:27231260

  20. Experiencias y repercusión de una formación en ética de investigación

    PubMed Central

    Rupaya, Carmen Rosa García

    2012-01-01

    El presente artículo tiene como propósito describir los logros y repercusiones de la capacitación en ética de la investigación que brinda el Centro Interdisciplinario de Estudios en Bioética de la Universidad de Chile, sirviendo de estímulo, motivación y orientación a profesionales que requieren conocer y aplicar las normas y el raciocinio conducente a la deliberación de los problemas en esta disciplina. Asimismo, describe cómo este conocimiento genera un efecto multiplicador en aspectos tales como la participación en un comité de ética de la investigación (CEI), organización de cursos y creación y desarrollo de líneas de investigación, que repercuten en publicaciones realizadas con estudiantes de posgrado. Relata además los contenidos y estrategias didácticas que pueden ser empleados en cursos de ética y bioética para estudiantes de estomatología y concluye mencionando la aplicación práctica de esta capacitación en los ámbitos docente, institucional y de investigación. PMID:24482556

  1. REFORZANDO LAS CAPACIDADES EN INVESTIGACIÓN EN INFORMÁTICA PARA LA SALUD GLOBAL EN LA REGIÓN ANDINA A TRAVÉS DE LA COLABORACIÓN INTERNACIONAL

    PubMed Central

    Curioso, Walter H.; García, Patricia J.; Castillo, Greta M.; Blas, Magaly M.; Perez-Brumer, Amaya; Zimic, Mirko

    2011-01-01

    RESUMEN Para mejorar la salud global y bienestar de una población se requiere de recursos humanos capacitados, no solo en el campo de la medicina y salud, sino también en el campo de la informática. Desafortunadamente, los programas de entrenamiento e investigación en informática biomédica en países en desarrollo son escasos y poco documentados. El objetivo del presente trabajo es reportar los resultados del primer Taller Internacional de Expertos en Informática para la región andina que se llevó a cabo en marzo de 2010 en Lima y que incluye la descripción de nueve casos de estudio procedentes de instituciones de América Latina. En el taller participaron 23 expertos latinoamericanos, quienes discutieron la necesidad de entrenamiento e investigación multidisciplinaria en informática biomédica en áreas prioritarias para América Latina. Además, se estableció la Red QUIPU debido a la necesidad de ampliar y consolidar una red de investigación y entrenamiento a nivel regional y global. PMID:21152740

  2. Shanghai Delta Complex

    SciTech Connect

    Hart, R.E.; Hoffman, P.F.; Parker, R.W.

    1988-01-01

    The upper Eocene Yegua Formation expands dramatically across a regional system of growth faults into an area generally 12-15 km wide, extending at least from the western edge of the Houston sale dome basin to the San Marcos arch. Within this area, the expanded Yegua trend has yielded, since 1982, at least seven noteworthy discoveries: Toro Grande and Lost Bridge fields in Jackson County, and Black Owl, Shanghai, Shanghai East, El Campo, and Phase Four fields in Wharton County. During each of several postulated Yegua sea level drops, this flexure became a focal point for deltaic deposition of excellent reservoir-quality sands. Shanghai, Shanghai East, and El Campo fields are located within what the writers have labeled the ''Shanghai delta complex.'' Integration of seismic and well data in this vicinity shows a marked increase in the expansion indices of growth faults, and moderately thick progradational sand sequences have accumulated immediately downthrow. This structural-stratigraphic pattern, as well as internal bedding characteristics and other lithologic data observed, is believed typical of deltas deposited along the Yegua shelf margin.

  3. Expanded Yegua

    SciTech Connect

    Hart, R.E.; Grayson, S.; Benes, J.

    1988-01-01

    The upper Eocene Yegua Formation expands dramatically across a regional flexure generally 12-15 km wide. During each of several postulated Yegua sea level drops, this flexure became a focal point for deltaic deposition of good to excellent reservoir-quality sands. From the western edge of the Houston salt dome basin to the San Marcos arch, this trend has yielded, since 1982, at least seven noteworthy discoveries: Toro Grande and Lost Bridge fields in Jackson County, and Black Owl, Shanghai, Shanghai East, El Campo, and Phase Four fields in Wharton County, Texas. El Campo field in Wharton County, Texas, was discovered in December 1985 by Ladd Petroleum Corporation with the drilling of the Ladd Petroleum 1 Popp well. Mud logs acquired while drilling indicated that a very sandy reservoir, with encouraging quantities of natural gas and condensate had been encountered. Subsequent open-hold logging generated more questions than answers about the prospective sand section. Additional open hole logs (EPT/ML,SHDT) were run to identify what turned out to be an extremely laminated sand-shale sequence over 400 ft thick. Subsequent development drilling and the acquisition of a 120 ft whole core provided valuable data in analyzing this prolific, geopressured natural gas and condensate Yegua reservoir. Whole-core data, open-hole logs, and computer logs were integrated to develop petro-physical evaluation procedures and to determine the environment of deposition. El Campo field is believed to represent an extremely thick, delta front slope to distal delta front facies.

  4. The ALTEA/ALTEINO projects: studying functional effects of microgravity and cosmic radiation

    NASA Technical Reports Server (NTRS)

    Narici, L.; Belli, F.; Bidoli, V.; Casolino, M.; De Pascale, M. P.; Di Fino, L.; Furano, G.; Modena, I.; Morselli, A.; Picozza, P.; Reali, E.; Rinaldi, A.; Ruggieri, D.; Sparvoli, R.; Zaconte, V.; Sannita, W. G.; Carozzo, S.; Licoccia, S.; Romagnoli, P.; Traversa, E.; Cotronei, V.; Vazquez, M.; Miller, J.; Salnitskii, V. P.; Lowenstein, D. (Principal Investigator)

    2004-01-01

    The ALTEA project investigates the risks of functional brain damage induced by particle radiation in space. A modular facility (the ALTEA facility) is being implemented and will be operated in the International Space Station (ISS) to record electrophysiological and behavioral descriptors of brain function and to monitor their time dynamics and correlation with particles and space environment. The focus of the program will be on abnormal visual perceptions (often reported as "light flashes" by astronauts) and the impact on retinal and brain visual structures of particle in microgravity conditions. The facility will be made available to the international scientific community for human neurophysiological, electrophysiological and psychophysics experiments, studies on particle fluxes, and dosimetry. A precursor of ALTEA (the 'Alteino' project) helps set the experimental baseline for the ALTEA experiments, while providing novel information on the radiation environment onboard the ISS and on the brain electrophysiology of the astronauts during orbital flights. Alteino was flown to the ISS on the Soyuz TM34 as part of mission Marco Polo. Controlled ground experiments using mice and accelerator beams complete the experimental strategy of ALTEA. We present here the status of progress of the ALTEA project and preliminary results of the Alteino study on brain dynamics, particle fluxes and abnormal visual perceptions. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.

  5. Theory of Intrinsic Spin Torque Due to Interface Spin-Orbit Coupling

    NASA Astrophysics Data System (ADS)

    Kalitsov, Alan; Chshiev, Mairbek; Butler, William; Mryasov, Oleg

    2014-03-01

    The effect of intrinsic spin torque due to spin-orbit coupling (SOC) at the interface between thin ferromagnetic film and non-magnetic metal has attracted significant fundamental and applied research interest. We report quantum theory of SOC driven spin torque (SOT) within the Rashba model of SOC and two-band tight binding (TB) Hamiltonian including s-d exchange interactions (J). We employ the non-equilibrium Green Function formalism and find that SOT to the first order in SOC has symmetry consistent with the earlier quasi-classical diffusive theory. An obvious benefit of the proposed approach is the expression for the SOT given in terms of TB parameters which enables a physically transparent analysis of the dependencies of SOT on material specific parameters such as Rashba SOC constant, hopping integral, Fermi level and J. On the basis of analytical and numerical results we discuss trends in strength of SOT and its correlation with the Spin Hall conductivity. This work was supported in part by C-SPIN, STARnet, a Semiconductor Research Corporation program, sponsored by MARCO and DARPA.

  6. Depositional framework, hydrostratigraphy, and uranium mineralization of the Oakville Sandstone (Miocene), Texas Coastal Plain

    SciTech Connect

    Galloway, W.E.; Henry, C.D.; Smith, G.E.

    1982-01-01

    The Oakville Sandstone (Miocene) of the Texas Coastal Plain comprises a major sand-rich fluvial system composed of deposits of several major and minor rivers that originated within Texas and surrounding states. Broad bed-load fluvial axes, including the Hebbronville, George West, and New Davy trends, lie south of the San Marcos Arch and host significant reserves of uranium. To the north, the Moulton streamplain consists of deposits of numerous small, flashy to ephemeral streams that drained the inland margin of the Coastal Plain. The Burton/Penn mixed-load fluvial axes traverse the Coastal Plain in the area of the modern Colorado and Brazos Rivers. Each fluvial axis consists of diagnostic facies deposited in channel, crevasse splay, and floodplain environments. Sand percentage, sand-body dimensions and lateral relationships, and composition vary systematically among the axes. Overall transmissivity of the Oakville Formation, which closely corresponds to the Jasper aquifer system in conventional hydrostratigraphic terminology, correlates directly with mapped facies composition and trend. Uranium deposit size relates directly to associated aquifer transmissivity. Commercial uranium deposits lie within channel and interbedded sheet-splay sands in or along the margin of major fluvial belts, typically near shallow faults. Mineralization occurs along narrow, elongate fronts separating altered, but commonly resulfidized, host sand from epigenetically sulfidized reduced sand. Deposits show pronounced spatial zoning of trace metals and iron sulfide, carbonate, and locally, clay mineral phases across the mineralization front. 62 references, 34 figures, 6 tables.

  7. Archaeometallurgy in Messina: Iron Slug From A Dig at Blog P, Laboratory Analyses and Interpretation.

    NASA Astrophysics Data System (ADS)

    Caterina, Ingoglia; Maurizio, Triscari; Giuseppe, Sabatino

    The archaeological site in Via La Farina, Block P, in Messina, is unique in many ways, due also to the high quantity of samples of iron slag. The slag was examined to identify the production centres of such materials, and, after characterization, was compared to similar material, exclusively for product typology, from different archaeological sites in the province of Messina, situated in the Peloritani Mountains (Messina city, S. Marco d'Alunzio, Milazzo, Francavilla di Sicilia, Novara di Sicilia as well as the archaeological site of Halaesa, near Tusa). Mineralogical characterization of the phases carried out by X-ray diffractometry (XRD) and Rietveld data elaboration, morphological study of slag findings and a semi-quantitative analysis by scanning electronic microscope (SEM+EDX) were performed. A chemical investigation was carried out by electron probe micro analysis (EPMA), to determine major element,. Minor and trace elements were determined by LA-ICP-MS. All the examined slag is related to iron metallurgy, and, in the case of Via La Farina, there is firm archaeological evidence pinpointing to smelting activity.

  8. Artesunate reduces serum lipopolysaccharide in cecal ligation/puncture mice via enhanced LPS internalization by macrophages through increased mRNA expression of scavenger receptors.

    PubMed

    Li, Bin; Yu, Mengchen; Pan, Xichun; Ren, Chuanliang; Peng, Wei; Li, Xiaoli; Jiang, Weiwei; Zheng, Jiang; Zhou, Hong

    2014-01-01

    Innate immunity is the first line of defense in human beings against pathogen infection; monocytes/macrophages are the primary cells of the innate immune system. Recently, macrophages/monocytes have been discovered to participate in LPS clearance, and the clearance efficiency determines the magnitude of the inflammatory response and subsequent organ injury. Previously, we reported that artesunate (AS) protected sepsis mice against heat-killed E. coli challenge. Herein, we further confirmed that AS protected cecal ligation/puncture (CLP) sepsis mice. Its protection on sepsis mice was related to not only reduction of pro-inflammatory cytokines and serum LPS levels but also improvement of liver function. Based on the fact that AS did not directly bind and neutralize LPS, we hypothesized that the reduction of serum LPS level might be related to enhancement of LPS internalization and subsequent detoxification. Our results showed that AS increased FITC-LPS internalization by peritoneal macrophage and liver Kupffer cell, but enhancement of LPS internalization by AS was not related to the clathrin-dependent pathway. However, AS induced mRNA expression of important scavenger receptors (SRs); SR-A and MARCO mRNA expression was upregulated, suggesting that AS enhancement of LPS internalization and inhibition of pro-inflammatory cytokines was related to changes in mRNA expression of SRs. PMID:24441569

  9. Astronomía en la cultura

    NASA Astrophysics Data System (ADS)

    López, A.; Giménez Benitez, S.; Fernández, L.

    La Astronomía en la Cultura es el estudio interdisciplinario a nivel global de la astronomía prehistórica, antigua y tradicional, en el marco de su contexto cultural. Esta disciplina abarca cualquier tipo de estudios o líneas de investigación en que se relacione a la astronomía con las ciencias humanas o sociales. En ella se incluyen tanto fuentes escritas, relatos orales como fuentes arqueológicas, abarcando entre otros, los siguientes temas: calendarios, observación práctica, cultos y mitos, representación simbólica de eventos, conceptos y objetos astronómicos, orientación astronómica de tumbas, templos, santuarios y centros urbanos, cosmología tradicional y la aplicación ceremonial de tradiciones astronómicas, la propia historia de la astronomía y la etnoastronomía (Krupp, 1989) (Iwaniszewski, 1994). En nuestro trabajo abordamos la historia y situación actual de esta disciplina, sus métodos y sus relaciones con otras áreas de investigación.

  10. Role of contact resistance in the effective spin relaxation rate in graphene spin valves

    NASA Astrophysics Data System (ADS)

    Stecklein, Gordon; Anugrah, Yoska; Li, Jing; Koester, Steven J.; Crowell, Paul

    Recent experiments (Maassen et al., PRB 86 235408 (2012), Idzuchi et al., PRB 91 241407(R) (2015)) have identified the role of finite contact resistances in determining the spin lifetime in graphene based on Hanle measurements of lateral spin valves. We have investigated this effect in spin valves fabricated using Co/AlOx tunnel barriers and graphene grown by chemical vapor deposition. By carrying out non-local spin valve and Hanle measurements over a wide range of gate voltages, we observe a variation in the spin signal that can be explained by the role of the contacts. Using the measured interface resistance, we quantify the degree of contact-induced spin sinking as the ratio of the contact resistance to the channel spin resistance and show that the variation in spin signal is explained by variation in this spin sinking parameter. By properly accounting for the effect of the contact resistance, we measure a spin lifetime that varies between 150-500 picoseconds. This work was supported by NSF ECCS-1124831, the NRI NEB program, and C-SPIN, a SRC STARNET center sponsored by MARCO and DARPA.

  11. Asbestos between science and myth. A 6,000-year story.

    PubMed

    Bianchi, Claudio; Bianchi, Tommaso

    2015-01-01

    Asbestos was used in making pottery in Eastern Finland from around 4000 B.C. In the ancient era and in the Middle Ages, magic properties were frequently attributed to this mineral. In the first century A.D., the Latin encyclopaedist Pliny the Elder reported in his Historia Naturalis that asbestos protects against all poisonings, particularly that of magicians. Moreover, asbestos was often found in places of worship, in Rome as well as in Athens and in Jerusalem. In the Middle Ages asbestos was identified with some animals, such as the salamander and certain white rodents. With such appearance, the mineral  had a huge success in Western as well as in Eastern literature and the fine arts. Marco Polo (1254-1324) in the Milione tried to deny that asbestos was a salamander. Despite its noxious effects, asbestos continues to be used in much of the world. In the 21st century it seems to be maintaining its quality as a magic stone. PMID:25744309

  12. Embedding Quantum Simulator

    NASA Astrophysics Data System (ADS)

    di Candia, Roberto; Mejia, Bernabé; Castillo, Hernan; Simon Pedernales, Julen; Casanova, Jorge; Solano, Enrique

    2014-03-01

    We introduce the concept of embedding quantum simulator, a paradigm allowing efficient computation of dynamical quantities requiring full quantum tomography in a standard quantum simulator (one-to-one quantum simulator). The concept consists in the suitable encoding of a simulated quantum dynamics in the enlarged Hilbert space of an embedding quantum simulator. In this manner, non-trivial quantities are mapped onto physical observables, overcoming the necessity of full tomography, and reducing drastically the experimental requirements. As examples, we discuss how to evaluate entanglement monotones and time correlation functions, each in a suitable embedding quantum simulator. Finally, we expect that the proposed embedding framework paves the way for a general theory of enhanced one-to-one quantum simulators. This work is supported by Spanish MINECO FIS2012-36673-C03-02; UPV/EHU UFI 11/55; UPV/EHU PhD fellowship; Basque Government IT472-10; SOLID, CCQED, PROMISCE, SCALEQIT EU projects; and Marco Polo PUCP grant.

  13. A civic engagement paradigm for reforming health administration education and recreating the community.

    PubMed

    Renick, Oren; Metzler, Leanne; Murray, Jennifer; Renick, Judy

    2005-01-01

    The education of students of health administration has traditionally combined both the theoretical and practical to enhance and balance the learning experience. Classroom exposure to the principles of management, law, organizations, and finance is coupled with problem solving, practicum, internship, and administrative residency experiences. However, just as recent years have seen the developmentof courses from managed care and alternative delivery systems to total quality management and continuous quality improvement, there is also emerging an awareness of the need to enhance the practical side of the learning equation. Perhaps this need is finding expression in curricular opportunities for students to learn from a participatory model known as civic engagement (CE). CE is a way of integrating academic study and community service to strengthen learning while promoting civic and personal responsibility to strengthen communities. Based on experiences with graduate and undergraduate students spanning the last ten years at Texas State University--San Marcos (Texas State), it is suggested that a CE paradigm has been developed within the Department of Health Administration that merits consideration by other programs of health administration. As a model for change, it has the potential for reforming both health administration education and most other higher education disciplines as well. PMID:15887851

  14. Quark Matter 2011 (QM11) Quark Matter 2011 (QM11)

    NASA Astrophysics Data System (ADS)

    2011-12-01

    International Advisory Committee Antinori, FedericoPaic, Guy Braun-Munzinger, PeterPajares, Carlos Cifarelli, LuisaPeitzmann, Thomas Erazmus, BarbaraRedlich, Krzysztof Eskola, KariRiccati, Lodovico Gaardhøje, Jens JørgenRoland, Gunther Gale, CharlesRoy, Christelle Gelis, FrancoisSchukraft, Jürgen Giubellino, PaoloSinha, Bikash Greiner, CarstenSrivastava, Dinesh Gyulassy, MiklosStachel, Johanna Harris, JohnSteinberg, Peter Hatsuda, TetsuoStroth, Joachim Heinz, UlrichSugitate, Toru Jacak, BarbaraTserruya, Itzhak Karsch, FrithjofVelkovska, Julia Kharzeev, DimaWang, Enke Kodama, TakeshiWang, Xin, Nian Lévai, PéterWessels, Johannes Manko, VladislavXu, Nu Müller, BerndtZajc, William Ollitrault, Jean-Yves Organizing Committee Arleo, FrancoisDupieux, Pascal Bastid, NicoleFurget, Christophe Bourgeois, Marie-LaureGranier de Cassagnac, Raphael Bregant, MarcoGuernane, Rachid Carminati, FedericoHervet, Carnita Castillo, JavierKuhn, Christian Cheynis, BrigitteOlivier, Nathalie Conesa, DelValle, Zaida Connor, MichelleRenshall, Lucy Crochet, PhilippeSuire, Christophe Delagrange, HuguesTihinen, Ulla Program Committee Schutz, Yves (Chair)Baldisseri, Alberto Wiedemann, Urs (co-Chair)Safarik, Karel Aurenche, Patrick

  15. Elemental characterization, sources and wind dependence of PM1 near Venice, Italy

    NASA Astrophysics Data System (ADS)

    Valotto, Gabrio; Squizzato, Stefania; Masiol, Mauro; Zannoni, Daniele; Visin, Flavia; Rampazzo, Giancarlo

    2014-06-01

    In this paper, PM1 elemental composition and relative sources have been investigated near Venice (Eastern Po Valley, Italy). Considering the lack of information on PM1 composition in this area and the general poor knowledge of emission profiles, this study can give useful information to better understand the source profile and the dispersion of finer particles. A sampling campaign was carried out in two sampling sites located inside the "Marco Polo" international airport of Venice. Elemental composition on PM1 samples was characterized by inductively coupled plasma optical emission spectroscopy. Five sources were identified and quantified by using the positive matrix factorization receptor model: heavy oil combustion, road traffic, airplane tire-wear, glassmaking and mixed combustions. The role of local atmospheric circulation was investigated by studying the source contributions as a function of wind velocity. Days characterized by low dispersion (lower wind speed and higher wind calm with respect to full period rose) showed a higher contribution for all sources, and a glassmaking contribution increase linked to wind blowing from South, where the artistic glass district of Venice is located.

  16. Measuring enthalpy of sublimation of volatiles by means of micro-thermogravimetry for the study of water and organic in planetary environments

    NASA Astrophysics Data System (ADS)

    Dirri, F.; Palomba, E.; Longobardo, A.; Zampetti, E.; Biondi, D.; Boccaccini, A.; Pantalei, S.; Zinzi, A.

    In this work, we present a new experimental set up to infer the enthalpy of sublimation for a known specie of dicarboxylic acid, i.e. adipic acid. This type of acids, with various concentrations are present in different environments (e.g. marine, rural, urban). The experiment is performed in the framework of the VISTA (Volatile In Situ Thermogravimetry Analyser) project, an instrument currently under study for the ESA Cosmic Vision proposed mission MarcoPolo-R. The enthalpy of sublimation of adipic acid was measured by means of micro-thermogravimetric analysis (mu -TGA), a widely used technique to investigate condensation/sublimation and absorption/desorption processes of volatile compounds. The measurements were performed with a 10 MHz temperature controlled piezoelectric crystal microbalance (PCM), placed in a vacuum chamber (10-6 mbar). The obtained enthalpy of sublimation is (123±16) kJ× mol-1, a value in good agreement with literature within 10%. This result (connected to the deposition rate curve, from 30 o to 75 oC), demonstrates the capability of our device to perform this kind of measurements.

  17. Women in media in the Philippines: from stereotype to liberation.

    PubMed

    Fernandez, D G

    1987-01-01

    The success of women in the Philippine print and electronic media is contrasted with the negative image in which they are presented in mass media such as television, radio, comics, tabloids and magazines. Philippine women began entering journalism early in the century, becoming established in the female oriented press by the 1960s. As the repression of the Marcos regime intensified, women journalists excelled in writing vanguard pieces, using allusion, allegory, indirection or metaphor, interviewing prisoners, founding alternative newspapers and even initiating the successful boycott of the 3 major crony papers when Aquino was killed. The participation of women in television journalism is parallel, but more limited due to the nature of the medium. Women's cultural role as multi-track organizers of family, finance and work is credited for this success. Dozens of names with titles and paper names are cited, as well as tabulated in an appendix. In contrast, women's image in the popular publications and electronic media is that of sex object, victim, ideal submissive wife-mother, or gracious lady shows little evidence of improving. This deleterious, backward and inaccurate image is likely due to all-male ownership, management and profit motive of these popular, vernacular mass media. PMID:12281075

  18. Mathematical modeling of postcombustion in a KOBM converter

    SciTech Connect

    Gou, H.; Irons, G.A.; Lu, W.-K. )

    1993-02-01

    A mathematical model has been developed to describe gas flow, combustion reactions, and heat transfer in converter-type steelmaking processes. The k-[epsilon] two-equation turbulent model, a finite reaction model, and the DeMarco-Lockwood flux model have been incorporated in this model to deal with the turbulent flow, postcombustion reactions, and radiation heat transfer. Local gaseous flow patterns, temperature, and heat flux distributions were calculated for a 300 tonne Kloeckner Oxygen Blowing Maximillanshuette (KOBM) converter. Comparison between the heat-transfer fluxes calculated based on the model and those measured industrially indicates the validity of the model in this application. The postcombustion has been found to be determined by the decarburization rate (DCR) which is directly related to the hardness of blowing not by the entrainment of surrounding gas to the oxygen jet as previously reported. The model revealed that about 20 pct of what is normally considered to be recovered heat has actually been lost through the vessel wall and to the lance. It is shown that this model is useful in studying the detailed mechanisms of postcombustion to optimize operations in converter-type steelmaking processes.

  19. Larval descriptions of the family Porcellanidae: A worldwide annotated compilation of the literature (Crustacea, Decapoda)

    PubMed Central

    Vela, María José; González-Gordillo, Juan Ignacio

    2016-01-01

    Abstract For most of the family Porcellanidae, which comprises 283 species, larval development remains to be described. Full development has been only described for 52 species, while part of the larval cycle has been described for 45 species. The importance of knowing the complete larval development of a species goes beyond allowing the identification of larval specimens collected in the plankton. Morphological larval data also constitute a support to cladistic techniques used in the establishment of the phylogenetic status (see Hiller et al. 2006, Marco-Herrero et al. 2013). Nevertheless, the literature on the larval development of this family is old and widely dispersed and in many cases it is difficult to collect the available information on a particular taxon. Towards the aim of facilitating future research, all information available on the larval development of porcellanids has been compiled. Following the taxonomic checklist of Porcellanidae proposed by Osawa and McLaughlin (2010), a checklist has been prepared that reflects the current knowledge about larval development of the group including larval stages and the method used to obtain the larvae, together with references. Those species for which the recognised names have been changed according to Osawa and McLaughlin (2010) are indicated. PMID:27081332

  20. CD163 Binding to Haptoglobin-Hemoglobin Complexes Involves a Dual-point Electrostatic Receptor-Ligand Pairing*

    PubMed Central

    Nielsen, Marianne Jensby; Andersen, Christian Brix Folsted; Moestrup, Søren Kragh

    2013-01-01

    Formation of the haptoglobin (Hp)-hemoglobin (Hb) complex in human plasma leads to a high affinity recognition by the endocytic macrophage receptor CD163. A fast segregation of Hp-Hb from CD163 occurs at endosomal conditions (pH <6.5). The ligand binding site of CD163 has previously been shown to involve the scavenger receptor cysteine-rich (SRCR) domain 3. This domain and the adjacent SRCR domain 2 of CD163 contain a consensus motif for a calcium-coordinated acidic amino acid triad cluster as originally identified in the SRCR domain of the scavenger receptor MARCO. Here we show that site-directed mutagenesis in each of these acidic triads of SRCR domains 2 and 3 abrogates the high affinity binding of recombinant CD163 to Hp-Hb. In the ligand, Hp Arg-252 and Lys-262, both present in a previously identified CD163 binding loop of Hp, were revealed as essential residues for the high affinity receptor binding. These findings are in accordance with pairing of the calcium-coordinated acidic clusters in SRCR domains 2 and 3 with the two basic Arg/Lys residues in the Hp loop. Such a two-point electrostatic pairing is mechanistically similar to the pH-sensitive pairings disclosed in crystal structures of ligands in complex with tandem LDL receptor repeats or tandem CUB domains in other endocytic receptors. PMID:23671278

  1. Tissue-resident macrophages protect the liver from ischemia reperfusion injury via a heme oxygenase-1-dependent mechanism.

    PubMed

    Devey, Luke; Ferenbach, David; Mohr, Elodie; Sangster, Kathryn; Bellamy, Christopher O; Hughes, Jeremy; Wigmore, Stephen J

    2009-01-01

    Kupffer cells are the resident macrophage population of the liver and have previously been implicated in the pathogenesis of hepatic ischemia-reperfusion injury (IRI). Kupffer cells are the major site of expression of hepatic heme oxygenase-1 (HO-1), which has been shown to have anti-inflammatory actions and to protect animals and cells from oxidative injury. Kupffer cells and circulating monocytes were selectively ablated using liposomal clodronate (LC) in the CD11b DTR mouse before induction of hepatic ischemia. Kupffer cell depletion resulted in loss of HO-1 expression and increased susceptibility to hepatic IRI, whereas ablation of circulating monocytes did not affect IRI phenotype. Targeted deletion of HO-1 rendered mice highly susceptible to hepatic IRI. In vivo, HO-1 deletion resulted in pro-inflammatory Kupffer cell differentiation characterized by enhanced Ly6c and MARCO (macrophage receptor with collagenous structure) expression as well as decreased F4/80 expression, mirrored by an expansion in immature circulating monocytes. In vitro, HO-1 inhibition throughout macrophage differentiation led to increased cell numbers, and pro-inflammatory Ly6c+ CD11c- F4/80- phenotype. These data support a critical role for tissue-resident macrophages in homeostasis following ischemic injury, and a co-dependence of HO-1 expression and tissue-resident macrophage differentiation. PMID:19002167

  2. Structural and electrical characterization of NbO2 vertical devices grown on TiN coated SiO2/Si substrate

    NASA Astrophysics Data System (ADS)

    Joshi, Toyanath; Borisov, Pavel; Lederman, David

    Due to its relatively high MIT temperature (1081 K) and current-controlled negative differential resistance, NbO2 is a robust candidate for memory devices and electrical switching applications. In this work, we present in-depth analysis of NbO2 thin film vertical devices grown on TiN coated SiO2/Si substrates using pulsed laser deposition (PLD). Two of the films grown in 1 mTorr and 10 mTorr O2/Ar (~7% O2) mixed growth pressures were studied. The formation of NbO2 phase was confirmed by Grazing Incidence X-ray Diffractometry (GIXRD), X-ray Photoelectron Spectroscopy (XPS) and current vs. voltage measurements. A probe station tip (tip size ~2 μm) or conductive AFM tip was used as a top and TiN bottom layer was used as a bottom contact. Device conductivity showed film thickness and contact size dependence. Current pulse measurements, performed in response to applied triangular voltage pulses, showed a non-linear threshold switching behavior for voltage pulse durations of ~100 ns and above. Self-sustained current oscillations were analyzed in terms of defect density presented in the film. Supported by FAME (sponsored by MARCO and DARPA, Contract 2013-MA-2382), WV Higher Education Policy Commission Grant (HEPC.dsr.12.29), and WVU SRF. We also thank S. Kramer from Micron for providing the TiN-coated Si substrates.

  3. Conference Committees: Conference Committees

    NASA Astrophysics Data System (ADS)

    2009-09-01

    International Programm Committee (IPC) Harald Ade NCSU Sadao Aoki University Tsukuba David Attwood Lawrence Berkeley National Laboratory/CXRO Christian David Paul Scherrer Institut Peter Fischer Lawrence Berkeley National Laboratory Adam Hitchcock McMaster University Chris Jacobsen SUNY, Stony Brook Denis Joyeux Lab Charles Fabry de l'Institut d'Optique Yasushi Kagoshima University of Hyogo Hiroshi Kihara Kansai Medical University Janos Kirz SUNY Stony Brook Maya Kiskinova ELETTRA Ian McNulty Argonne National Lab/APS Alan Michette Kings College London Graeme Morrison Kings College London Keith Nugent University of Melbourne Zhu Peiping BSRF Institute of High Energy Physics Francois Polack Soleil Christoph Quitmann Paul Scherrer Institut Gnther Schmahl University Gttingen Gerd Schneider Bessy Hyun-Joon Shin Pohang Accelerator Lab Jean Susini ESRF Mau-Tsu Tang NSRRC Tony Warwick Lawrence Berkeley Lab/ALS Local Organizing Committee Christoph Quitmann Chair, Scientific Program Charlotte Heer Secretary Christian David Scientific Program Frithjof Nolting Scientific Program Franz Pfeiffer Scientific Program Marco Stampanoni Scientific Program Robert Rudolph Sponsoring, Financials Alfred Waser Industry Exhibition Robert Keller Public Relation Markus Knecht Computing and WWW Annick Cavedon Proceedings and Excursions and Accompanying Persons Program Margrit Eichler Excursions and Accompanying Persons Program Kathy Eikenberry Excursions and Accompanying Persons Program Marlies Locher Excursions and Accompanying Persons Program

  4. Influence of quantum confinement and strain on orbital polarization of strained four-layer LaNiO3 superlattices: a DFT+DMFT study

    NASA Astrophysics Data System (ADS)

    Park, Hyowon; Millis, Andrew; Marianetti, Chris

    Here we use the combination of density functional theory and dynamical mean field theory to study Ni d orbital polarization in strained LaNiO3/LaAlO3 superlattices consisting of four layers of nominally metallic NiO2 and four layers of insulating AlO2 separated by LaO layers. The layer-resolved orbital polarization is calculated as a function of strain and analysed in terms of structural, quantum confinement, and correlation effects. The overall dependence of orbital polarization on strain in superlattices is qualitatively consistent with recent X-ray absorption spectroscopy and resonant reflectometry data. However, interesting differences of detail are found depending on the sign of strain. Under tensile strain, the two inequivalent Ni ions display orbital polarization similar to that calculated for strained bulk LaNiO3 and observed in experiment. Compressive strain produces a larger dependence of orbital polarization on Ni position and even the inner Ni layer exhibits orbital polarization different from that calculated for strained bulk LaNiO3. The quantum confinement effect is as important as the strain effect and more stronger for tensile strain. This work is supported by DOE ER-046169 and FAME, one of six centers of STARnet, a Semiconductor Research Corporation program sponsored by MARCO and DARPA.

  5. [Uriel García Cáceres, prominent leader and teacher of public health in Peru].

    PubMed

    Ugarte Ubilluz, Oscar

    2014-01-01

    Dr. Uriel García Cáceres, prominent physician, researcher and Peruvian historian, was born in the city of Cusco in 1922. He studied medicine at Universidad Nacional Mayor de San Marcos (1942-1950). He was influenced by Dr. Pedro Weiss and as a result he worked in the field of Pathological Anatomy, where he made substantial discoveries such as the description of kidney nodules associated with the verrucous stage of bartonellosis or Carrion’s disease. His most important contributions are in the paleopathology field, in which he helped create a better understanding of Peruvian ancient pathology. Dr. García Cáceres also participated in the political arena; he was Peru's Minister of Health, a position in which he served selflessly and always working for the good of the health of all Peruvians. At 91 years old, he is always tenacious and cheerful, and above all, he is a teacher with a readiness to learn. PMID:24718543

  6. Host Transcriptional Profiles and Immunopathologic Response following Mycobacterium avium subsp. paratuberculosis Infection in Mice

    PubMed Central

    Shin, Min-Kyoung; Park, Hongtae; Shin, Seung Won; Jung, Myunghwan; Lee, Su-Hyung; Kim, Dae-Yong; Yoo, Han Sang

    2015-01-01

    Paratuberculosis or Johne’s disease is a chronic granulomatous enteropathy in ruminants caused by Mycobacterium avium subsp. paratuberculosis (MAP) infection. In the present study, we examined the host response to MAP infection in spleens of mice in order to investigate the host immunopathology accompanying host-pathogen interaction. Transcriptional profiles of the MAP-infected mice at 3 and 6 weeks p.i. showed severe histopathological changes, whereas those at 12 weeks p.i. displayed reduced lesion severity in the spleen and liver. MAP-infected mice at 3 and 6 weeks p.i. showed up-regulation of interferon-related genes, scavenger receptor, and complement components, suggesting an initial innate immune reaction, such as macrophage activation, bactericidal activity, and macrophage invasion of MAP. Concurrently, MAP-infected mice at 3 and 6 weeks p.i. were also suggested to express M2 macrophage phenotype with up-regulation of Mrc1, and Marco and down-regulation of MHC class II, Ccr7, and Irf5, and canonical pathways related to the T cell response including ICOS-ICOSL signaling in T helper cells, calcium-induced T lymphocyte apoptosis, and CD28 signaling in T helper cell. These results provide information which furthers the understanding of the immunopathologic response to MAP infection in mice, thereby providing insights valuable for research into the pathogenesis for MAP infection. PMID:26439498

  7. Epidemiological and histopathological profile of cutaneous melanoma at a center in northeastern Brazil from 2000 to 2010*

    PubMed Central

    Vilanova, Camila Maria Arruda; Lages, Rafael Bandeira; Ribeiro, Sahâmia Martins; Almeida, Isabella Parente; dos Santos, Lina Gomes; Vieira, Sabas Carlos

    2013-01-01

    BACKGROUND While representing only 3-4% of malignant skin tumors, cutaneous melanoma is the most aggressive and lethal. Statistical knowledge about the biological behavior of this tumor is essential for guiding daily outpatient practice and aiding public health policies. OBJECTIVES To analyze the profile of patients with cutaneous melanoma attending a pathology department in Teresina (state of Piauí) between 2000 and 2010. METHODS Retrospective study of melanoma patients diagnosed between 2000 and 2010 in the São Marcos Hospital in the city of Teresina. The pathology laboratory reports were studied and all the statistical analyses performed using SPSS 19.0. RESULTS A total of 25 in situ, 199 invasive and 89 metastatic melanomas of unknown primary site were observed. Histological types found were nodular (52.8%), superficial spreading melanoma (18.6%), acral (10.6%) and lentigo maligna (9.5%). In 144 (73.4%) cases the Breslow thickness was >1 mm. Metastasis was found in 28.6% of invasive melanomas and nodular melanoma, Clark IV/ V, Breslow > 1 mm, mitotic index ≥ 6 and ulcerated lesions were more likely to metastasize. CONCLUSION Most melanomas presented Breslow> 1mm. The main factors associated with metastasis were nodular type, Clark IV / V, Breslow> 1mm, mitotic index ≥ 6 and ulcerated lesions. PMID:24068125

  8. The effect of sea level changes on fault reactivation potential in Portugal

    NASA Astrophysics Data System (ADS)

    Neves, M. C.; Cabral, J.; Luttrell, K.; Figueiredo, P.; Rockwell, T.; Sandwell, D.

    2015-09-01

    The aim of this study is to assess the impact of sea level changes on both the stress field and the potential of fault reactivation in west Iberia. The analysis is applied to a set of five active faults distributed across Portugal, selected for representing predominant fault directions and for being seismically active. The results show that the rise of sea level since the Last Glacial Maximum has produced flexural effects with distinct impacts on different faults. The Coulomb stress changes induced by the sea level rise along the S. Marcos-Quarteira (south Portugal) and the Horseshoe (offshore SW Iberia) faults are found to be extremely small, independently of the elastic plate thickness. These faults are thus unaffected by flexural effects related to ocean loading, and are unlikely to possess any paleoseismic record of this phenomenon. In contrast, the eustatic sea level rise during the late Pleistocene could have raised the Coulomb stress by 0.5-1 MPa along the Manteigas-Vilariça-Bragança (north Portugal) and Lower Tagus Valley (Lisbon area) fault systems. Such stress perturbations are probably sufficient to impact the seismic cycle of the Manteigas-Vilariça-Bragança fault, bringing it closer to failure and possibly triggering the earthquake clusters that have been observed in previous paleoseismologic studies.

  9. Avalanches of Singing Sand in the Laboratory

    NASA Astrophysics Data System (ADS)

    Dagois-Bohy, Simon; Courrech Du Pont, Sylvain; Douady, Stéphane

    2011-03-01

    The song of dunes is a natural phenomenon that has arisen travellers' curiosity for a long time, from Marco Polo to R.A. Bagnold. Scientific observations in the XXth century have shown that the sound is emitted during a shear flow of these particular grains, the free surface of the flow having coherent vibrations like a loud speaker. The sound emission is also submitted to a threshold effect with many parameters like humidity, flow speed, surface of the grains. The sound has been reproduced in laboratory avalanche experiments close to the natural phenomenon on field, but set in a channel with a hard bottom and a few centimeters of sand flowing, which contradicts explanations of the sound that involve a sand dune under the avalanche flow. Flow rates measurements also show the presence of a plug region in the flow above the sheared band, with the same characteristic length as the coherence zones of the sound. Finally we show experimentally that the Froude number, once modified to take into account the height of this plug band, is the parameter that sets the amplitude of the sound, and produces a threshold that depends on the grain type.

  10. Herschel observations of near-Earth objects: Encounters with the spacecraft and with the Earth

    NASA Astrophysics Data System (ADS)

    O'Rourke, L.; Müller, T.; Altieri, B.; Kiss, C.; Kùppers, M.; Barucci, M.; Bockelée-Morvan, D.; Gonzalez-Garcia, B.; Dotto, E.; Yoshikawa, M.; Carry, B.; Kidger, M.; Sanchez-Portal, M.; Vavrek, R.; Teyssier, D.; Marston, A.

    2014-07-01

    The Herschel MACH-11 (Measurements of 11 Asteroids & Comets with Herschel) Programme has as its prime goal to observe those asteroids & comets which have been or will be visited by spacecraft or those which are being studied with a similar goal in mind. The following near-Earth asteroids (NEAs) form part of the list of targets making up this program and will be addressed in this analysis: - 1999 JU_3 (Hayabusa 2 mission target) - 1999 RQ_{36} (OSIRIS-REx mission target) - 1996 FG_3 (Marco-Polo R backup mission target) - (99942) Apophis (Study target) An additional NEA (not part of the MACH-11 program) will also be reviewed, namely 2005 YU_{55}. Each target was observed using the PACS Photometer of the Herschel Space Observatory (Pilbratt et al 2010). The extracted fluxes from each observation campaign were fed into a thermophysical model which has been validated against a large database of asteroids including targets of other spacecraft missions. In all cases, radiometric properties of each target have been derived and will be presented, with their impact on already published data being analysed & discussed.

  11. AIDS as a political issue: working with the sexually prostituted in the Philippines.

    PubMed

    Tan, M; De Leon, A; Stoltzfus, B; O'donnell, C

    1989-07-01

    An estimated 200,000-500,000 men, women, and children work in prostitution in the Philippines in a variety of venues, including brothels, nightclubs, pubs, massage parlors, and other legitimate entertainment establishments. Few, however, are voluntary prostitutes. Many people who work as prostitutes have been recruited from the provinces, kept in conditions similar to slavery, and forced to earn money from prostitution to pay for their transportation, board, and lodging. Many prostitutes work in urban centers and tourist resorts in the countryside. During the 1970s, then President Ferdinand Marcos promoted tourism as a major industry, effectively marketing attractive Filipinas to tourists. Sex tourism has flourished in the country ever since. Thousands of prostitutes are also located in Olongapo and Angeles, 2 cities north of Manila, from where they serve the sexual desires of US military personnel. The presence of US military personnel in the Philippines has always been associated with prostitution. The country's social hygiene centers, prostitutes in Manila and Davao, and AIDS education are briefly discussed. PMID:12293749

  12. Direct growth of hexagonal boron nitride on epitaxial graphene

    NASA Astrophysics Data System (ADS)

    Mende, Patrick; Li, Jun; Feenstra, Randall

    2015-03-01

    In this work, we demonstrate recent attempts at achieving the direct growth of hexagonal boron nitride (h-BN) on epitaxial graphene. By exposing our graphene samples (grown on Si-face SiC) to a low-pressure (~ 1 ×10-4 Torr) background of borazine at temperatures exceeding 1000°C, we obtain in-situ low-energy electron diffraction patterns consistent with the presence of many randomly oriented grains of h-BN. We find that increasing the growth temperature leads to the development of a preferential orientation, with the h-BN aligning with the underlying SiC substrate. Atomic-force microscopy and low-energy electron microscopy (LEEM) show triangular crystals exceeding 1 μm in extent. Additionally, using a first-principles method for examining low-energy electron reflectivity spectra, we are capable of determining the coverage of h-BN on our samples. We show that our method is sufficiently robust to discriminate between various combinations of numbers of h-BN monolayers (MLs) and graphene MLs based on unique features in their spectra. Prospects for improvement of the h-BN crystallinity, as well as the controlled growth of a specific number of MLs are discussed. This work was supported in part by the Center for Low Energy Systems Technology (LEAST), one of the six SRC STARnet Centers, sponsored by MARCO and DARPA.

  13. Spall velocity measurements from laboratory impact craters

    NASA Technical Reports Server (NTRS)

    Polanskey, Carol A.; Ahrens, Thomas J.

    1986-01-01

    Spall velocities were measured for a series of impacts into San Marcos gabbro. Impact velocities ranged from 1 to 6.5 km/sec. Projectiles varied in material and size with a maximum mass of 4g for a lead bullet to a minimum of 0.04 g for an aluminum sphere. The spall velocities were calculated both from measurements taken from films of the events and from estimates based on range measurements of the spall fragments. The maximum spall velocity observed was 27 m/sec, or 0.5 percent of the impact velocity. The measured spall velocities were within the range predicted by the Melosh (1984) spallation model for the given experimental parameters. The compatability between the Melosh model for large planetary impacts and the results of these small scale experiments is considered in detail. The targets were also bisected to observe the internal fractures. A series of fractures were observed whose location coincided with the boundary of the theoretical near surface zone predicted by Melosh. Above this boundary the target material should receive reduced levels of compressive stress as compared to the more highly shocked region below.

  14. Impact-induced tensional failure in rock

    NASA Technical Reports Server (NTRS)

    Ahrens, Thomas J.; Rubin, Allan M.

    1993-01-01

    Planar impact experiments were employed to induce dynamic tensile failure in Bedford limestone. Rock disks were impacted with aluminum and polymethyl methacralate flyer plates at velocities of 10 to 25 m/s. This resulted in tensile stresses in the range of 11 to 160 MPa. Tensile stress durations of 0.5 and 1.3 microsec induced microcrack growth which in many experiments were insufficient to cause complete spalling of the samples. Velocity reduction, and by inference microcrack production, occurred in samples subjected to stresses above 35 MPa in the 1.3-microsec PMMA experiments and 60 MPa in the 0.5-microsec aluminum experiments. Apparent fracture toughnesses of 2.4 and 2.5 MPa m exp 1/2 are computed for the 1.3- and 0.5-microsec experiments. Three-dimensional impact experiments were conducted on 20 cm-sized blocks of Bedford limestone and San Marcos gabbro. Compressional wave velocity deficits up to 50-60 percent were observed in the vicinity of the crater. The damage decreases as about r exp -1.5 from the crater, indicating a dependence on the magnitude and duration of the tensile pulse.

  15. Transport of arginine and ornithine into isolated mitochondria of Saccharomyces cerevisiae.

    PubMed

    Soetens, O; Crabeel, M; El Moualij, B; Duyckaerts, C; Sluse, F

    1998-12-01

    In this work we have characterised the transport of L-arginine and L-ornithine into mitochondria isolated from a wild-type Saccharomyces cerevisiae strain and an isogenic arg11 knock-out mutant. The Arg11 protein (Arg11p) is a mitochondrial carrier required for arginine biosynthesis [Crabeel, M., Soetens, O., De Rijcke, M., Pratiwi, R. & Pankiewicz, R. (1996) J. Biol. Chem. 271, 25011-25019]. Reconstitution experiments have confirmed that it is an L-ornithine carrier also transporting L-arginine and L-lysine by order of decreasing affinity, but not L-histidine [Palmieri, L., De Marco, V., Iacobazzi, V., Palmieri, F., Runswick, M. & Walker, J. (1997) FEBS Lett. 410, 447-451]. Evidence is presented here that the mitochondrial inner membrane contains an L-arginine and L-ornithine transporting system distinct from Arg11p, in keeping with the arginine leaky phenotype of arg11 knock-out mutants. The newly characterised carrier, which we propose to name Bac1p (basic amino acid carrier), behaves as an antiporter catalysing the electroneutral exchange of the basic amino acids L-arginine, L-lysine, L-ornithine and L-histidine and displays the highest affinity for L-arginine (Km of 30 microM). L-Arginine uptake has a pH optimum in the range of 7.5-9 and is inhibited by several sulphydryl reagents, by pyridoxal 5'-phosphate and by cations. PMID:9874237

  16. Ultra-low-energy analog straintronics using multiferroic composites

    NASA Astrophysics Data System (ADS)

    Roy, Kuntal

    2014-03-01

    Multiferroic devices, i.e., a magnetostrictive nanomagnet strain-coupled with a piezoelectric layer, are promising as binary switches for ultra-low-energy digital computing in beyond Moore's law era [Roy, K. Appl. Phys. Lett. 103, 173110 (2013), Roy, K. et al. Appl. Phys. Lett. 99, 063108 (2011), Phys. Rev. B 83, 224412 (2011), Scientific Reports (Nature Publishing Group) 3, 3038 (2013), J. Appl. Phys. 112, 023914 (2012)]. We show here that such multiferroic devices, apart from performing digital computation, can be also utilized for analog computing purposes, e.g., voltage amplification, filter etc. The analog computing capability is conceived by considering that magnetization's mean orientation shifts gradually although nanomagnet's potential minima changes abruptly. Using tunneling magnetoresistance (TMR) measurement, a continuous output voltage while varying the input voltage can be produced. Stochastic Landau-Lifshitz-Gilbert (LLG) equation in the presence of room-temperature (300 K) thermal fluctuations is solved to demonstrate the analog computing capability of such multiferroic devices. This work was supported in part by FAME, one of six centers of STARnet, a Semiconductor Research Corporation program sponsored by MARCO and DARPA.

  17. Mass property control of a spin stabilized spacecraft with restrictive mission and weight constraints

    NASA Technical Reports Server (NTRS)

    Lang, W. E.; Ardvini, C.

    1985-01-01

    In the primary experiment of the spin stabilized San Marco D/L spacecraft, the drag effects on a light spherical shell coupled to a relatively massive center body will be measured. To achieve the precise mass property control, the centroids of both the shell and the center body must coincide with each other and with the center of pressure of the shell. Precise spin balancing is needed for launch and orbital stability, and the deployable antennas need accurate alignment. Corrective measures, developed after the preliminary mass measurements showed flaws in the mass property control, are described in detail. Inertia booms and a yo-yo despin system were developed as add-on units, spin balance measurements about all three geometric axes were used to define weight minimized correction within the outer shell envelope, and boom tip mass differentials were optimized for the most favorable inertia ratio margin achievable within the mission weight constraints. The weight versus orbital lifetime trade-offs were also considered.

  18. Transcriptome analysis highlights the conserved difference between embryonic and postnatal-derived alveolar macrophages.

    PubMed

    Gibbings, Sophie L; Goyal, Rajni; Desch, A Nicole; Leach, Sonia M; Prabagar, Miglena; Atif, Shaikh M; Bratton, Donna L; Janssen, William; Jakubzick, Claudia V

    2015-09-10

    Alveolar macrophages (AMs) reside on the luminal surfaces of the airways and alveoli where they maintain host defense and promote alveolar homeostasis by ingesting inhaled particulates and regulating inflammatory responses. Recent studies have demonstrated that AMs populate the lungs during embryogenesis and self-renew throughout life with minimal replacement by circulating monocytes, except under extreme conditions of depletion or radiation injury. Here we demonstrate that on a global scale, environment appears to dictate AM development and function. Indeed, transcriptome analysis of embryonic host-derived and postnatal donor-derived AMs coexisting within the same mouse demonstrated >98% correlation and overall functional analyses were similar. However, we also identified several genes whose expression was dictated by origin rather than environment. The most differentially expressed gene not altered by environment was Marco, a gene recently demonstrated to have enhancer activity in embryonic-derived but not postnatal-derived tissue macrophages. Overall, we show that under homeostatic conditions, the environment largely dictates the programming and function of AMs, whereas the expression of a small number of genes remains linked to the origin of the cell. PMID:26232173

  19. Therapeutic inflammatory monocyte modulation using immune-modifying microparticles.

    PubMed

    Getts, Daniel R; Terry, Rachael L; Getts, Meghann Teague; Deffrasnes, Celine; Müller, Marcus; van Vreden, Caryn; Ashhurst, Thomas M; Chami, Belal; McCarthy, Derrick; Wu, Huiling; Ma, Jin; Martin, Aaron; Shae, Lonnie D; Witting, Paul; Kansas, Geoffrey S; Kühn, Joachim; Hafezi, Wali; Campbell, Iain L; Reilly, David; Say, Jana; Brown, Louise; White, Melanie Y; Cordwell, Stuart J; Chadban, Steven J; Thorp, Edward B; Bao, Shisan; Miller, Stephen D; King, Nicholas J C

    2014-01-15

    Inflammatory monocyte-derived effector cells play an important role in the pathogenesis of numerous inflammatory diseases. However, no treatment option exists that is capable of modulating these cells specifically. We show that infused negatively charged, immune-modifying microparticles (IMPs), derived from polystyrene, microdiamonds, or biodegradable poly(lactic-co-glycolic) acid, were taken up by inflammatory monocytes, in an opsonin-independent fashion, via the macrophage receptor with collagenous structure (MARCO). Subsequently, these monocytes no longer trafficked to sites of inflammation; rather, IMP infusion caused their sequestration in the spleen through apoptotic cell clearance mechanisms and, ultimately, caspase-3-mediated apoptosis. Administration of IMPs in mouse models of myocardial infarction, experimental autoimmune encephalomyelitis, dextran sodium sulfate-induced colitis, thioglycollate-induced peritonitis, and lethal flavivirus encephalitis markedly reduced monocyte accumulation at inflammatory foci, reduced disease symptoms, and promoted tissue repair. Together, these data highlight the intricate interplay between scavenger receptors, the spleen, and inflammatory monocyte function and support the translation of IMPs for therapeutic use in diseases caused or potentiated by inflammatory monocytes. PMID:24431111

  20. Direct measurement of voltage-controlled reversal of the antiferromagnetic spin structure in magnetoelectric Cr2O3

    NASA Astrophysics Data System (ADS)

    Wang, Junlei; Binek, Christian

    The frequency dependence of the electric field induced magneto-optical Faraday effect is investigated in the magnetoelectric antiferromagnet chromia. Two electrically induced Faraday signals superimpose in proportion to the linear magnetoelectric susceptibility and the antiferromagnetic order parameter. The relative strength of these contributions is determined by the frequency of the probing light beam. It allows tuning the Faraday signal between extreme characteristics which follow the temperature dependence of the magnetoelectric susceptibility or solely that of the antiferromagnetic order parameter. The frequency dependence is analyzed in terms of electric dipole transitions of perturbed Cr3 + crystal-field states. The results lead to a table-top set-up allowing to measure voltage-controlled selection and temperature dependence of the antiferromagnetic order parameter. The Faraday rotation per applied voltage is independent of the sample thickness making the method scalable and versatile for thin film investigations. Scalability, compactness, and simplicity of the data analysis combined with low photon flux requirements make the Faraday approach advantageous for the investigation of the otherwise difficult to access voltage-controlled switching of antiferromagnetic domain states in magnetoelectric thin films. This project is supported by NRI via CNFD through tasks SRC 2398.001 and 2587.001, by C-SPIN, a SRC program, sponsored by MARCO and DARPA, and by NSF through Nebraska MRSEC DMR-1420645.

  1. Increased operational temperature of Cr2O3-based spintronic devices

    NASA Astrophysics Data System (ADS)

    Street, Michael; Echtenkamp, Will; Komesu, Takashi; Cao, Shi; Wang, Jian; Dowben, Peter; Binek, Christian

    Spintronic devices have been considered a promising path to revolutionizing the current data storage and memory technologies. This work is an effort to utilize voltage-controlled boundary magnetization of the magnetoelectric chromia (Cr2O3) to be implemented into a spintronic device. The electric switchable boundary magnetization of chromia can be used to voltage-control the magnetic states of an adjacent ferromagnetic layer. For this technique to be utilized in a spintronic device, the antiferromagnetic ordering temperature of chromia must be enhanced above the bulk value of TN = 307K. Previously, based on first principle calculations, boron doped chromia thin films were fabricated via pulsed laser deposition showing boundary magnetization at elevated temperatures. Measurements of the boundary magnetization were also corroborated by spin polarized inverse photoemission spectroscopy. Exchange bias of B-doped chromia was also investigated using magneto-optical Kerr effect, showing an increased blocking temperature from 307K. Further boundary magnetization measurements and spin polarized inverse photoemission measurements indicate the surface magnetization to an in-plane orientation from the standard perpendicular orientation. This project was supported by the SRC through CNFD, an SRC-NRI Center under Task ID (2398.001) and by C-SPIN, part of STARnet, sponsored by MARCO and DARPA (No. SRC 2381.001).

  2. Phylogeography and conservation genetics of a distinct lineage of sunfish in the Cuatro Ciénegas valley of Mexico.

    PubMed

    Coghill, Lyndon M; Hulsey, C Darrin; Chaves-Campos, Johel; García de Leon, Francisco J; Johnson, Steven G

    2013-01-01

    The valley of Cuatro Ciénegas, an aquatic oasis located in the Mexican Chihuahuan Desert, exhibits the highest level of endemism in North America and is a Mexican National Protected Area. However, little is known about the evolutionary distinctiveness of several vertebrate species present in the Cuatro Ciénegas valley. We conducted a phylogeographic study using mitochondrial haplotypes from the centrarchid fish Lepomis megalotis to determine if the populations found within the valley were evolutionarily distinct from populations outside the valley. We also examined if there was evidence of unique haplotypes of this sunfish within the valley. Genetic divergence of L. megalotis suggests populations within the valley are evolutionarily unique when compared to L. megalotis outside the valley. Significant mitochondrial sequence divergence was also discovered between L. megalotis populations on either side of the Sierra de San Marcos that bisects the valley. Our results reinforce previous studies that suggest the organisms occupying aquatic habitats not only within Cuatro Ciénegas but also in each of the two lobes of the valley generally deserve independent consideration during management decisions. PMID:24130826

  3. Satellite observations of zonal electric fields near sunrise in the equatorial ionosphere

    NASA Technical Reports Server (NTRS)

    Aggson, T. L.; Herrero, F. A.; Johnson, J. A.; Pfaff, R. F.; Laakso, H.; Maynard, N. C.; Moses, J. J.

    1995-01-01

    We report here on a number of examples of anomalous enhancements of eastward electric fields near sunrise in the equatorial ionospheric F-region. These examples were selected from the data base of the equatorial satellite, San Marco D (1988), which measured ionospheric electric fields during a period of solar minimum. The eastward electric fields reported correspond to vertical plasma drifts. The examples studied here are similar in signature and polarity to the pre-reversal electric field enhancements seen near sunset from ground-based radar systems. The morphology of these sunrise events, which are observed on about 14% of the morning-side satellite passes, are studied as a function of local zonal velocity, magnetic activity, geographic longitude and altitude. The nine events studied occur at locations where the zonal plasma flow is generally measured to be eastward, but reducing as a function of local time and at satellite longitudes where the magnetic declination has the opposite polarity as the declination of the sunrise terminator.

  4. Therapeutic Inflammatory Monocyte Modulation Using Immune-Modifying Microparticles

    PubMed Central

    Getts, Daniel R.; Terry, Rachael L.; Getts, Meghann Teague; Deffrasnes, Celine; Mller, Marcus; van Vreden, Caryn; Ashhurst, Thomas M.; Chami, Belal; McCarthy, Derrick; Wu, Huiling; Ma, Jin; Martin, Aaron; Shae, Lonnie D.; Witting, Paul; Kansas, Geoffrey S.; Khn, Joachim; Hafezi, Wali; Campbell, Iain L.; Reilly, David; Say, Jana; Brown, Louise; White, Melanie Y.; Cordwell, Stuart J.; Chadban, Steven J.; Thorp, Edward B.; Bao, Shisan; Miller, Stephen D.; King, Nicholas J. C.

    2014-01-01

    Inflammatory monocyte-derived effector cells play an important role in the pathogenesis of numerous inflammatory diseases. However, no treatment option exists that is capable of modulating these cells specifically. We show that infused negatively charged, immune-modifying microparticles (IMPs), derived from polystyrene, microdiamonds, or biodegradable poly(lactic-co-glycolic) acid, were taken up by inflammatory monocytes, in an opsonin-independent fashion, via the macrophage receptor with collagenous structure (MARCO). Subsequently, these monocytes no longer trafficked to sites of inflammation; rather, IMP infusion caused their sequestration in the spleen through apoptotic cell clearance mechanisms and, ultimately, caspase-3mediated apoptosis. Administration of IMPs in mouse models of myocardial infarction, experimental autoimmune encephalomyelitis, dextran sodium sulfateinduced colitis, thioglycollate-induced peritonitis, and lethal flavivirus encephalitis markedly reduced monocyte accumulation at inflammatory foci, reduced disease symptoms, and promoted tissue repair. Together, these data highlight the intricate interplay between scavenger receptors, the spleen, and inflammatory monocyte function and support the translation of IMPs for therapeutic use in diseases caused or potentiated by inflammatory monocytes. PMID:24431111

  5. Practices related to postpartum uterine involution in the Western Highlands of Guatemala

    PubMed Central

    Radoff, K.A.; Thompson, Lisa M.; Bly, KC; Romero, Carolina

    2013-01-01

    Background Guatemala has the third highest level of maternal mortality in Latin America. Postpartum haemorrhage is the main cause of maternal mortality. In rural Guatemala, most women rely on Traditional Birth Attendants (TBAs) during labour, delivery, and the postpartum period. Little is known about current postpartum practices that may contribute to uterine involution provided by Mam- and Spanish-speaking TBAs in the Western Highlands of Guatemala. Methods a qualitative study was conducted with 39 women who participated in five focus groups in the San Marcos Department of Guatemala. Questions regarding postpartum practices were discussed during four focus groups of TBAs and one group of auxiliary nurses. Results three postpartum practices believed to aid postpartum uterine involution were identified: use of the chuj (Mam) (Spanish, temazcal), a traditional wood-fired sauna-bath used by Mam-speaking women; herbal baths and teas; and administration of biomedicines. Conclusions TBAs provide the majority of care to women during childbirth and the postpartum period and have developed a set of practices to prevent and treat postpartum haemorrhage. Integration of these practices may prove an effective method to reduce maternal morbidity and mortality in the Western Highlands of Guatemala. PMID:22762787

  6. Three-body recombination of fermionic atoms in the ultracold limit

    NASA Astrophysics Data System (ADS)

    Suno, H.; Esry, B. D.; Greene, Chris H.

    2002-05-01

    While ultracold three-body recombination of bosons has been theoretically studied(B.D. Esry, C.H. Greene, and J.P. Burke, Jr., Phys. Rev. Lett. 83), 1751 (1999); E. Nielsen and J.H. Macek, ibid. 83, 1566 (1999); P.F. Bedaque, E. Braaten, and H.-W. Hammer, ibid. 85,908 (2000). because of its importance for Bose-Einstein condensates, similar studies have not been carried out for ultracold recombination of fermions. We will present the first such studies, examining the behavior of the recombination rate as a function of the p-wave scattering length(J.L. Bohn, Phys. Rev. A, 61) 053409 (2000). and comparing it with what is known about boson recombination. Implications for the many ongoing degenerate Fermi gas experiments(B. DeMarco and D.S. Jin, Science 285), 1703 (1999); K.M. O'Hara et al., Phys. Rev. Lett. 85, 2092 (2000); A.G. Truscott et al., Science 291, 2750 (2001). will also be discussed.

  7. In Search of New Spintronic Devices Using the Modular Approach

    NASA Astrophysics Data System (ADS)

    Camsari, Kerem Yunus

    There has been enormous progress in the last two decades, effectively combining spintronics and magnetics into a powerful force that is shaping the field of memory devices. At the same time, new materials and phenomena continue to be discovered at a very fast pace, providing an ever-increasing set of building blocks that could be exploited in designing functional devices of the future. Through careful benchmarking against available theory and experiment we recently established a set of ``elemental'' circuit modules representing a diverse range of materials and phenomena, which are continually updated. We will first show how these elemental modules can be integrated seamlessly to model both spintronic transport and nanomagnetic dynamics, starting from basic spin-valves and extending to complex experimental structures. We will then show how this framework can be used to design transistor-like spintronic devices to provide novel functionality compared to a standard complementary metal oxide semiconductor (CMOS) device. This approach allows us to incorporate the detailed physics of diverse sophisticated phenomena accurately into detailed circuit-level simulations to provide reliable estimates for the switching energy and delay of carefully designed devices. This work was supported in part by C-SPIN, one of six centers of STARnet, a Semiconductor Research Corporation program, sponsored by MARCO and DARPA and in part by the National Science Foundation through the NCN-NEEDS program, Contract 1227020-EEC.

  8. Climatic and geologic controls on the piezometry of the Querença-Silves karst aquifer, Algarve (Portugal)

    NASA Astrophysics Data System (ADS)

    Neves, Maria C.; Costa, Luis; Monteiro, José P.

    2016-01-01

    Karst aquifers in semi-arid regions, like Querença-Silves (Portugal), are particularly vulnerable to climate variability. For the first time in this region, the temporal structure of a groundwater-level time series (1985-2010) was explored using the continuous wavelet transform. The investigation focused on a set of four piezometers, two at each side of the S. Marcos-Quarteira fault, to demonstrate how each of the two sectors of the aquifer respond to climate-induced patterns. Singular spectral analysis applied to an extended set of piezometers enabled identification of several quasi-periodic modes of variability, with periods of 6.5, 4.3, 3.2 and 2.6 years, which can be explained by low-frequency climate patterns. The geologic forcing accounts for ~15 % of the differential variability between the eastern and western sectors of the aquifer. The western sector displays spatially homogenous piezometric variations, large memory effects and low-pass filtering characteristics, which are consistent with relatively large and uniform values of water storage capacity and transmissivity properties. In this sector, the 6.5-year mode of variability accounts for ~70 % of the total variance of the groundwater levels. The eastern sector shows larger spatial and temporal heterogeneity, is more reactive to short-term variations, and is less influenced by the low-frequency components related to climate patterns.

  9. Thermoelectric performance in ultra-thin transition metal dichalcogenides

    NASA Astrophysics Data System (ADS)

    Wickramaratne, Darshana; Zahid, Ferdows; Lake, Roger

    2014-03-01

    The thermoelectric figure of merit, ZT, is calculated for one to four monolayers of MoS2, MoSe2, WS2 and WSe2. The maximum ZT in this family of materials occurs in bilayer MoSe2. Its ZT value of 2.39 is a factor of 8 increase compared to that of the bulk at room temperature. The values for the power factors and ZT change non-monotonically as the film thicknesses are increased from a single monolayer up to four layers. In contrast to Bi2Te3, the peak value of ZT occurs at a thickness greater than a single monolayer for all 4 materials. The shape of the distribution of the valence band and the conduction band density of modes explains the enhanced thermoelectric performance that occurs for film thicknesses above a single monolayer. Ab-initio electronic structure calculations are used in a Landauer approach to calculate the thermoelectric transport coefficients. NSF and SRC-NRI project 2204.001 (NSF-1124733), FAME, one of six centers of STARnet, a SRC program sponsored by MARCO and DARPA. This work used the XSEDE which is supported by the NSF grant number OCI-1053575.

  10. Fermi velocity renormalization in misoriented graphene on hexagonal boron nitride

    NASA Astrophysics Data System (ADS)

    Neupane, Mahesh; Wickramaratne, Darshana; Ge, Supeng; Yin, Gen; Lake, Roger

    2014-03-01

    The electronic structure, Fermi velocity, and bandgap are calculated for graphene on BN as a function of misorientation angle. The Fermi velocity of Bernal stacked graphene on BN increases to 1.6 v0 where v0 is the velocity of single-layer graphene. For misorientation angles ranging from 5 to 27 degrees, the Fermi velocities of the Dirac electrons in graphene are relatively insensitive to the angle with values ranging between 0.85 and 0.9 v0. In addition, the bandgap at the Dirac point for rotated graphene on BN decreases by an order of magnitude compared to that of perfectly registered graphene on h-BN. This suggests a reduction in the interlayer coupling between the graphene and BN layers due to the rotation. Calculations are performed using density functional theory. This work is supported by FAME, one of six centers of STARnet, a SRC program sponsored by MARCO and DARPA, and a U.S. Dept. of Education GAANN Fellowship.This work used the resources at XSEDE (NSF Grant no: OCI-1053575) and Purdue University.

  11. THERMAP: a mid-infrared spectro-imager for space missions to small bodies in the inner solar system

    NASA Astrophysics Data System (ADS)

    Groussin, O.; Licandro, J.; Helbert, J.; Reynaud, J. L.; Levacher, P.; Reyes García-Talavera, M.; Alí-Lagoa, V.; Blanc, P. E.; Brageot, E.; Davidsson, B.; Delbó, M.; Deleuze, M.; Delsanti, A.; Diaz Garcia, J. J.; Dohlen, K.; Ferrand, D.; Green, S. F.; Jorda, L.; Joven Álvarez, E.; Knollenberg, J.; Kührt, E.; Lamy, P.; Lellouch, E.; Le Merrer, J.; Marty, B.; Mas, G.; Rossin, C.; Rozitis, B.; Sunshine, J.; Vernazza, P.; Vives, S.

    2016-02-01

    We present THERMAP, a mid-infrared spectro-imager for space missions to small bodies in the inner solar system, developed in the framework of the MarcoPolo-R asteroid sample return mission. THERMAP is very well suited to characterize the surface thermal environment of a NEO and to map its surface composition. The instrument has two channels, one for imaging and one for spectroscopy: it is both a thermal camera with full 2D imaging capabilities and a slit spectrometer. THERMAP takes advantage of the recent technological developments of uncooled microbolometer arrays, sensitive in the mid-infrared spectral range. THERMAP can acquire thermal images (8-18 μm) of the surface and perform absolute temperature measurements with a precision better than 3.5 K above 200 K. THERMAP can acquire mid-infrared spectra (8-16 μm) of the surface with a spectral resolution Δλ of 0.3 μm. For surface temperatures above 350 K, spectra have a signal-to-noise ratio >60 in the spectral range 9-13 μm where most emission features occur.

  12. Magneto-electric control of magnetization in a chain of circular nanomagnets as new paradigm for ultra low power binary information propagation

    NASA Astrophysics Data System (ADS)

    Salehi-Fashami, Mohammad; Al-Rashid, Mamun; Sun, Wei-Yang; Nordeen, Paul; Bandyopadhyay, Supriyo; Carman, Gregory; Atulasimha, Jayasimha

    Elliptical nanomagnets with bi stable magnetization states are traditionally employed for dipole coupled Bennett clocked nanomagnetic logic.Logic bits are propagated down a chain of nanomagnets by sequentially rotating their magnetizations with an electric field.In this talk,we present for the first time,the notion of replacing elliptical nanomagnets with circular nanomagnets that have no inherent shape anisotropy.The circular nanomagnets would develop bi stable magnetization orientations with the application of an electrical field to induce in-plane strain anisotropy.This new strategy provides two significant advantages for nanomagnetic logic applications:(i)re-orienting the magnetizations does not require overcoming a shape-anisotropy energy barrier and hence the electric field needed to reorient is reduced,leading to lower energy dissipation in the clocking process,and(ii)scalability to dimensions substantially smaller than what presently exists becomes possible. This work was supported by NSF CAREER grant CCF-1253370 and by FAME,one of six centers of STARnet,Semiconductor Research Corporation program sponsored by MARCO and DARPA.

  13. Heme oxygenase-1 in macrophages controls prostate cancer progression

    PubMed Central

    Nemeth, Zsuzsanna; Li, Mailin; Csizmadia, Eva; Döme, Balazs; Johansson, Martin; Persson, Jenny Liao; Seth, Pankaj; Otterbein, Leo; Wegiel, Barbara

    2015-01-01

    Innate immune cells strongly influence cancer growth and progression via multiple mechanisms including regulation of epithelial to mesenchymal transition (EMT). In this study, we investigated whether expression of the metabolic gene, heme oxygenase-1 (HO-1) in tumor microenvironment imparts significant effects on prostate cancer progression. We showed that HO-1 is expressed in MARCO-positive macrophages in prostate cancer (PCa) xenografts and human prostate cancers. We demonstrated that macrophage specific (LyzM-Cre) conditional deletion of HO-1 suppressed growth of PC3 xenografts in vivo and delayed progression of prostate intraepithelial neoplasia (PIN) in TRAMP mice. However, initiation and progression of cancer xenografts in the presence of macrophages lacking HO-1 resulted in loss of E-cadherin, a known marker of poor prognosis as well as EMT. Application of CO, a product of HO-1 catalysis, increased levels of E-cadherin in the adherens junctions between cancer cells. We further showed that HO-1-driven expression of E-cadherin in cancer cells cultured in the presence of macrophages is dependent on mitochondrial activity of cancer cells. In summary, these data suggest that HO-1-derived CO from tumor-associated macrophages influences, in part, E-cadherin expression and thus tumor initiation and progression. PMID:26418896

  14. OMI/Aura, SCIAMACHY/Envisat and GOME2/MetopA Sulphur Dioxide Estimate; The Case of Eastern Asia

    NASA Astrophysics Data System (ADS)

    Koukouli, M. E.; Balis, D. S.; Theys, N.; Brenot, H.; van Gent, J.; Hendrick, F.; Wang, T.; Valks, P.; Hedelt, P.; Lichtenberg, G.; Richter, A.; Krotkov, N.; Li, C.; van der A, R.

    2015-06-01

    The EU FP7 Monitoring and Assessment of Regional air quality in China using space Observations, Project Of Long-term sino-european co-Operation, MarcoPolo, project focuses on deriving emission estimates from space, http://www.marcopolo-panda.eu. Long term satellite observations of Sulphur Dioxide, SO2, over the greater China area from the SCIAMACHY/Envisat, GOME2/MetopA and OMI/Aura missions are compared and their relative strong points and limitations are discussed. For each satellite instrument, two different datasets are being analyzed in the same manner. Rigorous spatiotemporal statistical analysis based on novel analysis techniques is performed for each data set in order to reduce noise and biases and enhance pollution signals in satellite datasets. Furthermore, identification of point sources such as power plants, smelters and urban agglomerations, as well as definition of their relative contribution to the regional SO2 levels, form the main findings of this investigation. Trend analyses and their statistical representation help locate regions of interesting SO2 loading in China.

  15. Evaluation of satellite sulphur dioxide estimates from OMI/Aura, SCIAMACHY/Envisat and GOME2/MetopA

    NASA Astrophysics Data System (ADS)

    Koukouli, MariLiza; Balis, Dimitris; Theys, Nicolas; Brenot, Hugues; van Gent, Jeroen; Valks, Pieter; Hedelt, Pascal; Lichtenberg, Günter; Richter, Andreas; Krotkov, Nickolay; van der A, Ronald

    2015-04-01

    The EU FP7 Monitoring and Assessment of Regional air quality in China using space Observations, Project Of Long-term sino-european co-Operation, MarcoPolo, project focuses on deriving emission estimates from space and their refinement by spatial downscaling and by source sector apportionment. Satellite observations of suphur dioxide, SO2, over the greater China area are analyzed using novel techniques [Fioletov et al., 2011; 2013] in order to enhance the observational signal and provide a robust SO2 dataset for the region. Observations from the SCIAMACHY/Envisat, GOME2/MetopA and OMI/Aura missions are assessed in this work and their relative strengths and shortcomings discussed at length. Rigorous screening is applied to and presented for each data source, including a full length spatiotemporal statistical analysis. Furthermore, identification of point sources such as power plants and urban agglomerations, as well as the definition of their relative contribution to the general SO2 levels, form the basis of this investigation.

  16. [Experiences in the training of health human resources for the integral care of the victims of violence in a suburban area of Lima, Peru].

    PubMed

    Garmendia, Fausto; Perales, Alberto; Miranda, Eva; Mendoza, Pedro; Calderón, Walter; Miano, Jorge

    2010-01-01

    In the year 2003, in the Faculty of Medicine of the Universidad Nacional Mayor de San Marcos, the Permanent Program of Training for the Integral Attention of the Victims of Violence was created, has been training human resources for the comprehensive health care to victims of violence. In this sense, we was considered necessary to develop a methodology for health professionals, identifying their training needs and the conditions under how they work. It is in this context, that the year 2004, a base line study was delineated in the Microrred de Salud Huaycán, in the east of Lima city; that included diverse stages with a multisectorial approach with the aim to identify the training needs of the health professionals, as well as the evaluation of the logistic and administrative support for the development of training activities to diverse levels. In this paper, the procedures and principal results are exposed, in a succinct way. There was demonstrated that the population of Huaycán were affected by the sequels of the political violence; nevertheless, the health services have severe limited resources to give appropriate health care to victims of violence. The health professionals require an intensive training on this issue. An adequate logistic and administrative conditions allowed to carry out an appropriate training program. We suggest that this methodology will facilitate to construct products and instruments for a suitable and specific training for the integral health care to the victims of the violence. PMID:21308206

  17. Dispersión de velocidades en cúmulos de galaxias

    NASA Astrophysics Data System (ADS)

    Muriel, H.; García Lambas, D.; Quintana, H.; Infante, L.

    Se ha estudiado la dinámica de galaxias en cúmulos en base a una muestra de aproximadamente 4000 galaxias con estimas de velocidad radial pertenecientes a 40 cúmulos. Se desarrolló un algoritmo para identificar sub-estructuras del tipo ``grupos de galaxias". Una vez eliminada este tipo de sub-estructura se computaron los perfiles radiales de dispersión de velocidades (VDP) para los 40 cúmulos de galaxias. Dada las características de la muestra, fue posible estimar el VDP hasta grandes distancias del centro del cúmulo llegando en algunos casos hasta 7 Mpc-1. Los resultados indican que el 65% de los cúmulos presentan un VDP plano a grandes radios consistente con el modelo isotermo. Estos resultados son discutidos en el marco de las recientes controversias suscitadas respecto de la dinámica de los cúmulos vía los perfiles de temperaturas de cúmulos derivados de la emisión en rayos-X.

  18. Diffuse-Flow Conceptualization and Simulation of the Edwards Aquifer, San Antonio Region, Texas

    USGS Publications Warehouse

    Lindgren, R.J.

    2006-01-01

    A numerical ground-water-flow model (hereinafter, the conduit-flow Edwards aquifer model) of the karstic Edwards aquifer in south-central Texas was developed for a previous study on the basis of a conceptualization emphasizing conduit development and conduit flow, and included simulating conduits as one-cell-wide, continuously connected features. Uncertainties regarding the degree to which conduits pervade the Edwards aquifer and influence ground-water flow, as well as other uncertainties inherent in simulating conduits, raised the question of whether a model based on the conduit-flow conceptualization was the optimum model for the Edwards aquifer. Accordingly, a model with an alternative hydraulic conductivity distribution without conduits was developed in a study conducted during 2004-05 by the U.S. Geological Survey, in cooperation with the San Antonio Water System. The hydraulic conductivity distribution for the modified Edwards aquifer model (hereinafter, the diffuse-flow Edwards aquifer model), based primarily on a conceptualization in which flow in the aquifer predominantly is through a network of numerous small fractures and openings, includes 38 zones, with hydraulic conductivities ranging from 3 to 50,000 feet per day. Revision of model input data for the diffuse-flow Edwards aquifer model was limited to changes in the simulated hydraulic conductivity distribution. The root-mean-square error for 144 target wells for the calibrated steady-state simulation for the diffuse-flow Edwards aquifer model is 20.9 feet. This error represents about 3 percent of the total head difference across the model area. The simulated springflows for Comal and San Marcos Springs for the calibrated steady-state simulation were within 2.4 and 15 percent of the median springflows for the two springs, respectively. The transient calibration period for the diffuse-flow Edwards aquifer model was 1947-2000, with 648 monthly stress periods, the same as for the conduit-flow Edwards aquifer model. The root-mean-square error for a period of drought (May-November 1956) for the calibrated transient simulation for 171 target wells is 33.4 feet, which represents about 5 percent of the total head difference across the model area. The root-mean-square error for a period of above-normal rainfall (November 1974-July 1975) for the calibrated transient simulation for 169 target wells is 25.8 feet, which represents about 4 percent of the total head difference across the model area. The root-mean-square error ranged from 6.3 to 30.4 feet in 12 target wells with long-term water-level measurements for varying periods during 1947-2000 for the calibrated transient simulation for the diffuse-flow Edwards aquifer model, and these errors represent 5.0 to 31.3 percent of the range in water-level fluctuations of each of those wells. The root-mean-square errors for the five major springs in the San Antonio segment of the aquifer for the calibrated transient simulation, as a percentage of the range of discharge fluctuations measured at the springs, varied from 7.2 percent for San Marcos Springs and 8.1 percent for Comal Springs to 28.8 percent for Leona Springs. The root-mean-square errors for hydraulic heads for the conduit-flow Edwards aquifer model are 27, 76, and 30 percent greater than those for the diffuse-flow Edwards aquifer model for the steady-state, drought, and above-normal rainfall synoptic time periods, respectively. The goodness-of-fit between measured and simulated springflows is similar for Comal, San Marcos, and Leona Springs for the diffuse-flow Edwards aquifer model and the conduit-flow Edwards aquifer model. The root-mean-square errors for Comal and Leona Springs were 15.6 and 21.3 percent less, respectively, whereas the root-mean-square error for San Marcos Springs was 3.3 percent greater for the diffuse-flow Edwards aquifer model compared to the conduit-flow Edwards aquifer model. The root-mean-square errors for San Antonio and San Pedro Springs were

  19. Detection of salmonellae in different turtle species within a headwater spring ecosystem.

    PubMed

    Gaertner, James P; Hahn, Dittmar; Rose, Francis L; Forstner, Michael R J

    2008-04-01

    Sediments and water from the slough arm of Spring Lake, the headwaters of the San Marcos River, Texas, USA, as well as swabs from biofilms on carapaces and from the cloacae of 18 common musk turtles (Sternotherus odoratus), 21 red-eared sliders (Trachemys scripta elegans), nine Texas river cooters (Pseudemys texana), one snapping turtle (Chelydra serpentina serpentina), and three Guadalupe spiny soft-shell turtles (Apalone spinifera guadalupensis), caught at the same site, were analyzed for salmonellae by culture and molecular techniques. Although enrichment cultures from sediment and water samples were negative for salmonellae in polymerase chain reaction (PCR)-based analyses, this technique detected salmonellae in the enrichments from both carapaces and cloacae of 11 musk turtles (61%), eight red-eared sliders (38%), and the snapping turtle. Salmonellae could also be detected in the enrichments from the carapaces of two additional red-eared sliders and two Texas river cooters; the remaining samples were negative. Further characterization of isolates obtained from the enrichment cultures of seven selected individuals that represented all turtle species with salmonellae confirmed the presence of Salmonella enterica subspecies enterica, with serovars Rubislaw, Newport, Gaminara, and Thompson identified. These results demonstrate the presence of different strains of potentially human pathogenic salmonellae naturally occurring on several turtle species with different life histories even within supposedly pristine environments. PMID:18436690

  20. Larval descriptions of the family Porcellanidae: A worldwide annotated compilation of the literature (Crustacea, Decapoda).

    PubMed

    Vela, María José; González-Gordillo, Juan Ignacio

    2016-01-01

    For most of the family Porcellanidae, which comprises 283 species, larval development remains to be described. Full development has been only described for 52 species, while part of the larval cycle has been described for 45 species. The importance of knowing the complete larval development of a species goes beyond allowing the identification of larval specimens collected in the plankton. Morphological larval data also constitute a support to cladistic techniques used in the establishment of the phylogenetic status (see Hiller et al. 2006, Marco-Herrero et al. 2013). Nevertheless, the literature on the larval development of this family is old and widely dispersed and in many cases it is difficult to collect the available information on a particular taxon. Towards the aim of facilitating future research, all information available on the larval development of porcellanids has been compiled. Following the taxonomic checklist of Porcellanidae proposed by Osawa and McLaughlin (2010), a checklist has been prepared that reflects the current knowledge about larval development of the group including larval stages and the method used to obtain the larvae, together with references. Those species for which the recognised names have been changed according to Osawa and McLaughlin (2010) are indicated. PMID:27081332

  1. ALTEA/Alteino: studying functional effects of microgravity and cosmic radiation

    NASA Astrophysics Data System (ADS)

    Narici, L.; For

    ALTEA project is based on the development of a facility to be used in the experimental studies in the International Space Station (ISS), on particle flux, human electrophysiology and psychophysics, dosimetry. Aim of the project is to define and measure descriptors for the elctrophysiological brain functioning and to follow their dynamics and the correlations with space environments. A specific focus will be posed on the abnormal visual perceptions (such as the reported perception of phosphenes ("light flashes") in orbit) and the impact of particle in microgravity conditions. Other experiments could proficiently use the features of this facility. A precursor of ALTEA, project `Alteino' is helping in preparing the experimental baseline for the ALTEA experiments, while providing novel information on the radiation environment in the ISS and on the dynamics of the astronauts' electrophysiology during orbital flights. Alteino have flown in the ISS with mission Marco Polo, on the Soyuz TM34. We present here the results from the Alteino investigation on brain dynamics correlated with particle fluxes and anomalous phosphene perceptions. Preliminary electrophysiological works on the effects of transient heavy ion radiation of the eye/cortex, as obtained in in vivo on mice (ALTEA -MICE) are being conducted. Detailed accounts of particle fluences as measured by Alteino's telescope "SilEye3" and of ALTEA -MICE are given elsewhere in this conference.

  2. The ALTEA/ALTEINO projects: studying functional effects of microgravity and cosmic radiation.

    PubMed

    Narici, L; Belli, F; Bidoli, V; Casolino, M; De Pascale, M P; Di Fino, L; Furano, G; Modena, I; Morselli, A; Picozza, P; Reali, E; Rinaldi, A; Ruggieri, D; Sparvoli, R; Zaconte, V; Sannita, W G; Carozzo, S; Licoccia, S; Romagnoli, P; Traversa, E; Cotronei, V; Vazquez, M; Miller, J; Salnitskii, V P; Shevchenko, O I; Petrov, V P; Trukhanov, K A; Galper, A; Khodarovich, A; Korotkov, M G; Popov, A; Vavilov, N; Avdeev, S; Boezio, M; Bonvicini, W; Vacchi, A; Zampa, N; Mazzenga, G; Ricci, M; Spillantini, P; Castellini, G; Vittori, R; Carlson, P; Fuglesang, C; Schardt, D

    2004-01-01

    The ALTEA project investigates the risks of functional brain damage induced by particle radiation in space. A modular facility (the ALTEA facility) is being implemented and will be operated in the International Space Station (ISS) to record electrophysiological and behavioral descriptors of brain function and to monitor their time dynamics and correlation with particles and space environment. The focus of the program will be on abnormal visual perceptions (often reported as "light flashes" by astronauts) and the impact on retinal and brain visual structures of particle in microgravity conditions. The facility will be made available to the international scientific community for human neurophysiological, electrophysiological and psychophysics experiments, studies on particle fluxes, and dosimetry. A precursor of ALTEA (the 'Alteino' project) helps set the experimental baseline for the ALTEA experiments, while providing novel information on the radiation environment onboard the ISS and on the brain electrophysiology of the astronauts during orbital flights. Alteino was flown to the ISS on the Soyuz TM34 as part of mission Marco Polo. Controlled ground experiments using mice and accelerator beams complete the experimental strategy of ALTEA. We present here the status of progress of the ALTEA project and preliminary results of the Alteino study on brain dynamics, particle fluxes and abnormal visual perceptions. PMID:15803627

  3. Structure and transport of topological insulators on epitaxial graphene

    NASA Astrophysics Data System (ADS)

    Kally, James; Reifsnyder Hickey, Danielle; Lin, Yu-Chuan; Richardella, Anthony; Lee, Joon Sue; Robinson, Joshua; Mkhoyan, K. Andre; Samarth, Nitin

    Recent advancements in spintronics have shown that a class of materials, topological insulators (TI), can be used as a spin-current generator or detector. Topological insulators have protected surface states with the electron's spin locked to its momentum. To access these surface states, (Bi, Sb)2Te3 can be grown by molecular beam epitaxy to have the Fermi energy near the Dirac point so that transport occurs only through the spin-dependent surface states. Graphene is another 2D material of great interest for spintronics because of its very long spin diffusion length. This is an ideal material to act as a spin channel in devices. The van der Waals nature of the growth exhibited by 2D materials such as (Bi, Sb)2Te3 and graphene allows heterostructures to be formed despite the large lattice mismatch. We explore the structure and transport of (Bi, Sb)2Te3 grown on epitaxial graphene on 6H-SiC substrates for spintronic applications. This work was supported in part by C-SPIN and LEAST, two of the six centers of STARnet, a Semiconductor Research Corporation program, sponsored by MARCO and DARPA.

  4. Phonon engineering of electronic transport in hybrid nanotubes

    NASA Astrophysics Data System (ADS)

    Balandin, Alexander A.; Fonoberov, Vladimir A.

    2006-03-01

    Recently, a number of biological nanoscale objects, including tobacco mosaic viruses (TMV), have been employed as templates for assembly of inorganic nanostructures. This approach can potentially lead to a new method of fabrication of nanoelectronic circuits beyond conventional CMOS. Here we theoretically demonstrate that in addition to their role as nano-templates [1], the elastically soft TMVs can improve electron transport in the nanotubes grown on them [2]. In the simulated hybrid nanostructures, which consist of silicon or silica nanotubes on TMVs, the confined acoustic phonons are found to be redistributed between the nanotube shell and the acoustically soft virus enclosure. As a result, the low-temperature electron mobility in the hybrid TMV-silicon nanotube can increase up to a factor of four compared to that of an empty silicon nanotube [2]. Our estimates also indicate an enhancement of the low-temperature thermal conductivity in the TMV-silicon nanotube, which can lead to improvements in heat removal from the hybrid nanostructure-based circuits. The authors acknowledge the support of MARCO and its Functional Engineered Nano Architectonics (FENA) Focus Center. [1] W.L. Liu, K. Alim, A.A. Balandin et al., Appl. Phys. Lett. 86, 253108 (2005); [2] V.A. Fonoberov and A.A. Balandin, Nano Lett. 5, 1920 (2005).

  5. A minimal model for the structural energetics of VO2

    NASA Astrophysics Data System (ADS)

    Kim, Chanul; Marianetti, Chris; The Marianetti Group Team

    Resolving the structural, magnetic, and electronic structure of VO2 from the first-principles of quantum mechanics is still a forefront problem despite decades of attention. Hybrid functionals have been shown to qualitatively ruin the structural energetics. While density functional theory (DFT) combined with cluster extensions of dynamical mean-field theory (DMFT) have demonstrated promising results in terms of the electronic properties, structural phase stability has not yet been addressed. In order to capture the basic physics of the structural transition, we propose a minimal model of VO2 based on the one dimensional Peierls-Hubbard model and parameterize this based on DFT calculations of VO2. The total energy versus dimerization in the minimal mode is then solved numerically exactly using density matrix renormalization group (DMRG) and compared to the Hartree-Fock solution. We demonstrate that the Hartree-Fock solution exhibits the same pathologies as DFT+U, and spin density functional theory for that matter, while the DMRG solution is consistent with experimental observation. Our results demonstrate the critical role of non-locality in the total energy, and this will need to be accounted for to obtain a complete description of VO2 from first-principles. The authors acknowledge support from FAME, one of six centers of STARnet, a Semiconductor Research Corporation program sponsored by MARCO and DARPA.

  6. Interconnections between magnetic state and transport currents in antiferromagnetic Sr2IrO4

    NASA Astrophysics Data System (ADS)

    Tsoi, Maxim

    Interconnections between magnetic state and transport currents in ferromagnetic (F) heterostructures are the basis for spintronic applications, e.g. tunneling magnetoresistance and spin-transfer torque phenomena provide a means to read and write information in magnetic memory devices like STTRAM. Similar interconnections were proposed to occur in systems where F-components are replaced with antiferromagnets (AFM). We demonstrated experimentally the existence of such interconnections in antiferromagnetic Mott insulator Sr2IrO4: first, we found a very large anisotropic magnetoresistance (AMR) which can be used to monitor (read) the magnetic state of AFM; second, we demonstrated the feasibility of reversible resistive switching driven by high-density currents/high electric fields which can be used for writing in AFM memory applications. These results support the feasibility of AFM spintronics where antiferromagnets are used in place of ferromagnets. This work was supported in part by C-SPIN, one of six centers of STARnet, a Semiconductor Research Corporation program, sponsored by MARCO and DARPA, and by NSF grants DMR-1207577, DMR-1265162 and DMR-1122603.

  7. The Bizarre Spectral Variability of Central Stars of Planetary Nebulae

    NASA Astrophysics Data System (ADS)

    De Marco, Orsola; Wortel, S.; Bond, Howard E.; Harmer, Dianne

    2007-06-01

    A radial velocity (RV) survey to detect central stars in binary systems was carried out between 2002 and 2004. De Marco et al. (2004) reported that 10 out of 11 monitored stars exhibited strong RV variability, but periods were not detected. Since other mechanisms, such as wind variability, can cause apparent RV variations, we monitored 4 of the 10 RV-variable stars at echelle resolutions to determine the origin of the variability. Although RV changes are confirmed for all four stars, none of them can be ascribed to binarity at this time. However, only for IC4593 is wind variability able to explain most (though not all) spectral variability. For BD+332642, no wind and no pulsations appear to be the origin of the RV changes. Finally, M1-77 and M2-54, both known to be irregular photometric variables, exhibit dramatic RV and line shape variability of the hydrogen and HeI absorption lines, as well as large RV variability of weaker lines, which do not change in shape. There is no satisfactory explanation of this variability, though a combination of wind variability and pulsations is still the best guess at what makes these stars so variable. We suggest that luminous central stars are ill suited to detect spectroscopic binaries, because winds (and possibly pulsations) are pervasive and would mask even strong periodicities. It it likely that a sample of intrinsically faint central stars would more readily yield binary information.

  8. Importance of Large-Scale Wave Structure to Equatorial Spread F

    NASA Astrophysics Data System (ADS)

    Tsunoda, R. T.

    2008-12-01

    There is mounting evidence that large-scale wave structure (LSWS) is a more direct precursor of equatorial spread F (ESF) than the post-sunset rise (PSSR) of the equatorial F layer. Unambiguous experimental evidence, though limited, come from measurements by ALTAIR, a fully steerable incoherent-scatter radar, in situ measurements by low-altitude satellites in low-inclination orbits (AE-E, San Marco D), and total electron content measurements using satellites in low-inclination orbits. Less direct evidence is contained in seemingly extraneous traces in equatorial ionograms, which appear to be associated with LSWS and ESF. Clearly, a demonstration that these traces are indeed a direct consequence of LSWS is pivotal because such a demonstration would allow use of the extensive database of equatorial ionograms that exists to argue conclusively that LSWS is a central player in ESF generation. A demonstration of this kind will be presented, together with a description of experiments proposed for the Pacific sector, which involve the C/NOFS satellite, and how they will increase substantially our understanding of LSWS and ESF.

  9. Dynamic depositional and early diagenetic processes in a deep-water shelf setting, upper cretaceous Austin Chalk, North Texas

    SciTech Connect

    Hovorka, S.D.; Nance, H.S.

    1994-12-31

    The Austin Chalk of north Texas was deposited on a deep-water shelf north of the Sea Marcos Platform during a worldwide Coniacian and Santonian sea-level highstand. Transgressive (lowermost lower Austin Chalk), highstand (uppermost lower Austin Chalk), and regressive (middle and upper Austin Chalk) phases of cyclic chalk and marl sedimentation are recognized in excavations and tunnels created in Ellis County for the Superconducting Super Collider provide new evidence of sediment transport during Austin Chalk deposition. During transgression, bottom currents syndepositionally reworked nannoplankton oozes, incising channels as much as 120 ft across and 8 ft deep. Weakly burrowed channel fills having preservation of fine lamination document rapid infilling. Channel fills are composed of pyritized and carbonized wood and Inoceramus lag deposits, pellets, echinoderm fragments, and globigerinid grainstones, and coccolith ooze. During maximum highstand, bottom reworking was suppressed. Detrital content of highstand marls is low (>20 percent); organic content is high (1.4 to 3.5 percent). Coccolith preservation is excellent because of minimal diagenetic alteration. Regression is marked by resumed channel cutting and storm-bed winnowing in the middle and upper Austin Chalk. Suppressed resistivity log response and recessive weathering characteristics of the middle Austin Chalk are not primarily related to depositional environment but rather to increased input of volcanic ash during the accumulation of this interval. Early stabilization of ash produced clay-coated microfabrics in sediments that are otherwise similar to the transgressive deposits.

  10. An autopsy case of pneumococcal Waterhouse-Friderichsen syndrome with possible functional asplenia/hyposplenia

    PubMed Central

    Hata, Yukiko; Chiba, Takashi; Ohtani, Maki; Ishizawa, Shin; Nishida, Naoki

    2015-01-01

    We report an autopsy case of rapid progressive Waterhouse-Friderichsen syndrome (WFS) associated with Streptococcus pneumonia infection in a previously healthy man. Although he once visited a hospital about 6 hours before death, the both physical and serological examination did not show any sign of overwhelming infection. Autopsy showed massive adrenal hemorrhage without inflammation, and showed proliferation of gram positive cocci and microthrombosis in the vessels of many organs. The pathological change of respiratory tract was extremely minimal. Size and weight of the spleen possible decreased than normal. However, histological examination showed that obscuration of germinal center and decreasing the immunological cells of mantle and marginal zone. Immunohisitochemically, marked decreasing the marginal zone macrophages, which are positive for specific intercellular adhesion molecule grabbing nonintegrin receptor-1 (SIGN-R1) and macrophage receptor with collagenous structure (MARCO), were decreased comparing with age-matched control case. Polymerase chain reaction (PCR) assay using each DNA, extraction from formalin-fixed paraffin-embedded specimen (FFPE) samples of lung, adrenal gland, heart, spleen, and kidney showed positive the ply gene and the lytA gene specific for Streptococcus pneumonia. Present case showed possible acquired atrophy of spleen, especially decreasing marginal zone macrophage may correlate with rapid progression of sepsis of Streptococcus pneumonia with massive adrenal hemorrhage. In addition, present case showed the usefulness of PCR using FFPE for the postmortem diagnosis of WFS. PMID:26261663

  11. Zero field conductance singularity in two terminal ferromagnet-topological insulator device

    NASA Astrophysics Data System (ADS)

    Duan, Xiaopeng; Semenov, Yuriy G.; Kim, Ki Wook

    2014-03-01

    Spin-momentum interlocking of surface electronic states on 3D topological insulator (TI) grants the unique opportunity to generate electric current directed according to the spin polarization of injected electrons instead of the applied electric field. Such asymmetry in momentum distribution of injected electrons takes place in the vicinity of ferromagnetic contact but vanishes on the length of few mean free passes. We propose to use this property in two terminal devices consisting of two parallel ferromagnetic contacts deposited on the surface of 3D TI. When the injected spin polarization leads to electron momentum pointing towards the other electrode, it facilitate the direct transmission, resulting in a lower resistance; in contrast with a reversed bias, the spin-determined momentum points away from the other electrode, because of which the electrons could gain the right momentum only after multiple scatterings to approach the second electrode, thus resulting in a higher resistance. We stress that this asymmetry in the resistance keeps up to arbitrarily small applied voltage since it does not need the formation of space charge region that is essential in conventional diodes. The rectification ratio near zero voltage are estimated and potential application are discussed. This work was supported, in part, by the US Army Research Office and FAME (one of six centers of STARnet, a SRC program sponsored by MARCO and DARPA).

  12. Artesunate Reduces Serum Lipopolysaccharide in Cecal Ligation/Puncture Mice via Enhanced LPS Internalization by Macrophages through Increased mRNA Expression of Scavenger Receptors

    PubMed Central

    Li, Bin; Yu, Mengchen; Pan, Xichun; Ren, Chuanliang; Peng, Wei; Li, Xiaoli; Jiang, Weiwei; Zheng, Jiang; Zhou, Hong

    2014-01-01

    Innate immunity is the first line of defense in human beings against pathogen infection; monocytes/macrophages are the primary cells of the innate immune system. Recently, macrophages/monocytes have been discovered to participate in LPS clearance, and the clearance efficiency determines the magnitude of the inflammatory response and subsequent organ injury. Previously, we reported that artesunate (AS) protected sepsis mice against heat-killed E. coli challenge. Herein, we further confirmed that AS protected cecal ligation/puncture (CLP) sepsis mice. Its protection on sepsis mice was related to not only reduction of pro-inflammatory cytokines and serum LPS levels but also improvement of liver function. Based on the fact that AS did not directly bind and neutralize LPS, we hypothesized that the reduction of serum LPS level might be related to enhancement of LPS internalization and subsequent detoxification. Our results showed that AS increased FITC-LPS internalization by peritoneal macrophage and liver Kupffer cell, but enhancement of LPS internalization by AS was not related to the clathrin-dependent pathway. However, AS induced mRNA expression of important scavenger receptors (SRs); SR-A and MARCO mRNA expression was upregulated, suggesting that AS enhancement of LPS internalization and inhibition of pro-inflammatory cytokines was related to changes in mRNA expression of SRs. PMID:24441569

  13. Enhancing the capabilities of emigration countries to protect men and women destined for low-skilled employment: the case of the Philippines.

    PubMed

    Santo Tomas, P

    1999-01-01

    This study examined policies in receiving countries, evaluated their effectiveness in protecting low skilled Filipino migrant workers, and discusses the potential for quantifying and objectifying labor migrant gains or losses. Data were obtained from focus groups among 10 technical managers of the Philippine Overseas Employment Administration and interviews with 10 policy-makers in order to establish a hierarchy of aims in labor migration and policy indicators. The aims are identified as good jobs abroad, an orderly process, efficient and fair recruitment, and easy transfers of remittances. Findings are that Philippine policies facilitate remittance transfers. Government was least effective in ensuring orderliness. Government was fairly effective in ensuring fairness and efficiency and ensuring good jobs overseas. It succeeded the most in ensuring that nationals can easily transfer their earnings. Allocation data reveal that more resources were expended on searching for good jobs and least on fairness and efficiency. Remittances increased after mandatory remittances were ended as imposed by the Marcos regime. De-skilling often resulted from overseas employment, but rehired workers received better pay on their second and third assignments. This research was exploratory and more research is needed for developing sensitive indicators and refining the process of evaluating key government policies. The Philippine Development Policy that encourages labor migration and protection of overseas workers is a necessity during the ongoing Asian economic crisis. PMID:12322075

  14. 1998 astronaut candidates tour CCAS facilities

    NASA Technical Reports Server (NTRS)

    1999-01-01

    At Cape Canaveral Air Station, members of the 1998 astronaut candidate class (Group 17) pose in front of the Project Mercury monument at Launch Complex 14 during a tour of the station's facilities. This 13-foot-high astronomical symbol for the planet Mercury was constructed by General Dynamics, the Atlas airframe contractor, and dedicated in 1964 in honor of those who flew in the Mercury 7 capsule. The class is at Kennedy Space Center taking part in training activities, including a flight awareness program, as well as touring the OPF, VAB, SSPF, SSME Processing Facility, launch pads, SLF, Apollo/Saturn V Center, and the crew quarters. The U.S. candidates in the '98 class are Clayton C. Anderson, Lee J. Archambault, Tracy E. Caldwell (Ph.D.), Gregory E. Chamitoff (Ph.D.), Timothy J. Creamer, Christopher J. Ferguson, Michael J. Foreman, Michael E. Fossum, Kenneth T. Ham, Patricia C. Hilliard (M.D.), Gregory C. Johnson, Gregory H. Johnson, Stanley G. Love (Ph.D.), Leland D. Melvin, Barbara R. Morgan, William A. Oefelein, John D. Olivas (Ph.D.), Nicholas J.M. Patrick (Ph.D.), Alan G. Poindexter, Garrett E. Reisman (Ph.D.), Steven R. Swanson, Douglas H. Wheelock, Sunita L. Williams, Neil W. Woodward III, George D. Zamka; and the international candidates are Leopold Eyharts, Paolo Nespoli, Hans Schlegel, Roberto Vittori, Bjarni V. Tryggvason, and Marcos Pontes.

  15. 1998 astronaut candidates tour KSC facilities

    NASA Technical Reports Server (NTRS)

    1999-01-01

    On their tour of KSC, members of the 1998 astronaut candidate class (group 17) stop at the Space Shuttle Main Engine (SSME) Processing Facility for a close up look at a main shuttle engine. The class is taking part in training activities, including fire training and a flight awareness program, plus touring the OPF, VAB, SSPF, launch pads, SLF, Apollo/Saturn V Center, the crew headquarters, as well as the SSME Processing Facility. The U.S. candidates in the '98 class are Clayton C. Anderson, Lee J. Archambault, Tracy E. Caldwell (Ph.D.), Gregory E. Chamitoff (Ph.D.), Timothy J. Creamer, Christopher J. Ferguson, Michael J. Foreman, Michael E. Fossum, Kenneth T. Ham, Patricia C. Hilliard (M.D.), Gregory C. Johnson, Gregory H. Johnson, Stanley G. Love (Ph.D.), Leland D. Melvin, Barbara R. Morgan, William A. Oefelein, John D. Olivas (Ph.D.), Nicholas J.M. Patrick (Ph.D.), Alan G. Poindexter, Garrett E. Reisman (Ph.D.), Steven R. Swanson, Douglas H. Wheelock, Sunita L. Williams, Neil W. Woodward III, George D. Zamka; and the international candidates are Leopold Eyharts, Paolo Nespoli, Hans Schlegel, Roberto Vittori, Bjarni V. Tryggvason, and Marcos Pontes.

  16. 1998 astronaut candidates tour CCAS facilities copy form; photos beginning with 99PD are only availa

    NASA Technical Reports Server (NTRS)

    1999-01-01

    At Cape Canaveral Air Station, members of the 1998 astronaut candidate class (Group 17) pose in front of what remains of the launch tower at Launch Complex 34 during a tour of the station's facilities. During the Apollo Program, Launch Complex 34 was the site of the first Saturn I and Saturn IB launches, as well as the tragic fire in which the Apollo I astronauts lost their lives. The class is at Kennedy Space Center taking part in training activities, including a flight awareness program, as well as touring the OPF, VAB, SSPF, SSME Processing Facility, launch pads, SLF, Apollo/Saturn V Center, and the crew quarters. The U.S. candidates in the '98 class are Clayton C. Anderson, Lee J. Archambault, Tracy E. Caldwell (Ph.D.), Gregory E. Chamitoff (Ph.D.), Timothy J. Creamer, Christopher J. Ferguson, Michael J. Foreman, Michael E. Fossum, Kenneth T. Ham, Patricia C. Hilliard (M.D.), Gregory C. Johnson, Gregory H. Johnson, Stanley G. Love (Ph.D.), Leland D. Melvin, Barbara R. Morgan, William A. Oefelein, John D. Olivas (Ph.D.), Nicholas J.M. Patrick (Ph.D.), Alan G. Poindexter, Garrett E. Reisman (Ph.D.), Steven R. Swanson, Douglas H. Wheelock, Sunita L. Williams, Neil W. Woodward III, George D. Zamka; and the international candidates are Leopold Eyharts, Paolo Nespoli, Hans Schlegel, Roberto Vittori, Bjarni V. Tryggvason, and Marcos Pontes.

  17. 1998 astronaut candidates tour KSC facilities

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Members of the 1998 astronaut candidate class (group 17) learn about the use of the Space Shuttle Main Engine (SSME) Processing Facility. At left is one of the main shuttle engines. The class is at KSC for training activities, including fire training and a flight awareness program, plus touring the OPF, VAB, SSPF, launch pads, SLF, Apollo/Saturn V Center, the crew headquarters, as well as the SSME Processing Facility. The U.S. candidates in the '98 class are Clayton C. Anderson, Lee J. Archambault, Tracy E. Caldwell (Ph.D.), Gregory E. Chamitoff (Ph.D.), Timothy J. Creamer, Christopher J. Ferguson, Michael J. Foreman, Michael E. Fossum, Kenneth T. Ham, Patricia C. Hilliard (M.D.), Gregory C. Johnson, Gregory H. Johnson, Stanley G. Love (Ph.D.), Leland D. Melvin, Barbara R. Morgan, William A. Oefelein, John D. Olivas (Ph.D.), Nicholas J.M. Patrick (Ph.D.), Alan G. Poindexter, Garrett E. Reisman (Ph.D.), Steven R. Swanson, Douglas H. Wheelock, Sunita L. Williams, Neil W. Woodward III, George D. Zamka; and the international candidates are Leopold Eyharts, Paolo Nespoli, Hans Schlegel, Roberto Vittori, Bjarni V. Tryggvason, and Marcos Pontes.

  18. 1998 astronaut candidates tour KSC facilities

    NASA Technical Reports Server (NTRS)

    1999-01-01

    The 1998 astronaut candidate class (group 17) gather in the Space Shuttle Main Engine Processing (SSMEP) Facility. In the foreground is one of the main shuttle engines. The class is at KSC for training activities, including fire training and a flight awareness program, plus touring the OPF, SSME Processing Facility, VAB, SSPF, launch pads, SLF, Apollo/Saturn V Center and the crew headquarters. The U.S. candidates in the '98 class are Clayton C. Anderson, Lee J. Archambault, Tracy E. Caldwell (Ph.D.), Gregory E. Chamitoff (Ph.D.), Timothy J. Creamer, Christopher J. Ferguson, Michael J. Foreman, Michael E. Fossum, Kenneth T. Ham, Patricia C. Hilliard (M.D.), Gregory C. Johnson, Gregory H. Johnson, Stanley G. Love (Ph.D.), Leland D. Melvin, Barbara R. Morgan, William A. Oefelein, John D. Olivas (Ph.D.), Nicholas J.M. Patrick (Ph.D.), Alan G. Poindexter, Garrett E. Reisman (Ph.D.), Steven R. Swanson, Douglas H. Wheelock, Sunita L. Williams, Neil W. Woodward III, George D. Zamka; and the international candidates are Leopold Eyharts, Paolo Nespoli, Hans Schlegel, Roberto Vittori, Bjarni V. Tryggvason, and Marcos Pontes.

  19. 1998 astronaut candidates tour KSC

    NASA Technical Reports Server (NTRS)

    1999-01-01

    At the Apollo/Saturn V Center, some of the 1998 astronaut candidate class (group 17) line up for a photo while standing under the engines of the Saturn V rocket on display. The U.S. candidates include Clayton C. Anderson, Lee J. Archambault, Tracy E. Caldwell (Ph.D.), Gregory E. Chamitoff (Ph.D.), Timothy J. Creamer, Christopher J. Ferguson, Michael J. Foreman, Michael E. Fossum, Kenneth T. Ham, Patricia C. Hilliard (M.D.), Gregory C. Johnson, Gregory H. Johnson, Stanley G. Love (Ph.D.), Leland D. Melvin, Barbara R. Morgan, William A. Oefelein, John D. Olivas (Ph.D.), Nicholas J.M. Patrick (Ph.D.), Alan G. Poindexter, Garrett E. Reisman (Ph.D.), Steven R. Swanson, Douglas H. Wheelock, Sunita L. Williams, Neil W. Woodward III, George D. Zamka; and international candidates Leopold Eyharts, Paolo Nespoli, Hans Schlegel, Roberto Vittori, Bjarni V. Tryggvason, and Marcos Pontes. The class is at KSC for training activities, including fire training and a flight awareness program, plus touring the OPF, SSME Processing Facility, VAB, SSPF, launch pads, SLF, Apollo/Saturn V Center and the crew headquarters.

  20. 1998 astronaut candidates tour KSC facilities

    NASA Technical Reports Server (NTRS)

    1999-01-01

    On a raised platform in the Orbiter Processing Facility bay 3, members of the 1998 astronaut candidate class (group 17) look at the aft fuselage of the orbiter Atlantis. The class is at KSC for training activities, including fire training and a flight awareness program, plus touring the OPF, SSME Processing Facility, VAB, SSPF, launch pads, SLF, Apollo/Saturn V Center and the crew headquarters. The U.S. candidates in the '98 class are Clayton C. Anderson, Lee J. Archambault, Tracy E. Caldwell (Ph.D.), Gregory E. Chamitoff (Ph.D.), Timothy J. Creamer, Christopher J. Ferguson, Michael J. Foreman, Michael E. Fossum, Kenneth T. Ham, Patricia C. Hilliard (M.D.), Gregory C. Johnson, Gregory H. Johnson, Stanley G. Love (Ph.D.), Leland D. Melvin, Barbara R. Morgan, William A. Oefelein, John D. Olivas (Ph.D.), Nicholas J.M. Patrick (Ph.D.), Alan G. Poindexter, Garrett E. Reisman (Ph.D.), Steven R. Swanson, Douglas H. Wheelock, Sunita L. Williams, Neil W. Woodward III, George D. Zamka; and the international candidates are Leopold Eyharts, Paolo Nespoli, Hans Schlegel, Roberto Vittori, Bjarni V. Tryggvason, and Marcos Pontes.

  1. 1998 astronaut candidates tour KSC

    NASA Technical Reports Server (NTRS)

    1999-01-01

    At the Apollo/Saturn V Center, some of the 1998 astronaut candidate class (group 17) line up for a photo during a tour of facilities at KSC. The U.S. candidates include Clayton C. Anderson, Lee J. Archambault, Tracy E. Caldwell (Ph.D.), Gregory E. Chamitoff (Ph.D.), Timothy J. Creamer, Christopher J. Ferguson, Michael J. Foreman, Michael E. Fossum, Kenneth T. Ham, Patricia C. Hilliard (M.D.), Gregory C. Johnson, Gregory H. Johnson, Stanley G. Love (Ph.D.), Leland D. Melvin, Barbara R. Morgan, William A. Oefelein, John D. Olivas (Ph.D.), Nicholas J.M. Patrick (Ph.D.), Alan G. Poindexter, Garrett E. Reisman (Ph.D.), Steven R. Swanson, Douglas H. Wheelock, Sunita L. Williams, Neil W. Woodward III, George D. Zamka; and international candidates Leopold Eyharts, Paolo Nespoli, Hans Schlegel, Roberto Vittori, Bjarni V. Tryggvason, and Marcos Pontes. The class is at KSC for training activities, including fire training and a flight awareness program, plus touring the OPF, SSME Processing Facility, VAB, SSPF, launch pads, SLF and the crew headquarters.

  2. 1998 astronaut candidates tour KSC facilities

    NASA Technical Reports Server (NTRS)

    1999-01-01

    On the grounds of the Kennedy Space Center, members of the 1998 astronaut candidate class (Group 17) watch as candidate Sunita L. Williams practices using firefighting equipment during fire training. The class is at KSC for training activities, including a flight awareness program, plus touring the OPF, VAB, SSPF, SSME Processing Facility, launch pads, SLF, Apollo/Saturn V Center, and the crew quarters. The other U.S. candidates in the '98 class are Clayton C. Anderson, Lee J. Archambault, Tracy E. Caldwell (Ph.D.), Gregory E. Chamitoff (Ph.D.), Timothy J. Creamer, Christopher J. Ferguson, Michael J. Foreman, Michael E. Fossum, Kenneth T. Ham, Patricia C. Hilliard (M.D.), Gregory C. Johnson, Gregory H. Johnson, Stanley G. Love (Ph.D.), Leland D. Melvin, Barbara R. Morgan, William A. Oefelein, John D. Olivas (Ph.D.), Nicholas J.M. Patrick (Ph.D.), Alan G. Poindexter, Garrett E. Reisman (Ph.D.), Steven R. Swanson, Douglas H. Wheelock, Neil W. Woodward III, George D. Zamka; and the international candidates are Leopold Eyharts, Paolo Nespoli, Hans Schlegel, Roberto Vittori, Bjarni V. Tryggvason, and Marcos Pontes.

  3. 1998 astronaut candidates tour KSC facilities

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Members of the 1998 astronaut candidate class (group 17) look at the aft of a Space Shuttle Main Engine (SSME) (right). The class is at KSC for training activities, including fire training and a flight awareness program, plus touring the OPF, VAB, SSPF, launch pads, SLF, Apollo/Saturn V Center, the crew headquarters, as well as the SSME Processing Facility. The U.S. candidates in the '98 class are Clayton C. Anderson, Lee J. Archambault, Tracy E. Caldwell (Ph.D.), Gregory E. Chamitoff (Ph.D.), Timothy J. Creamer, Christopher J. Ferguson, Michael J. Foreman, Michael E. Fossum, Kenneth T. Ham, Patricia C. Hilliard (M.D.), Gregory C. Johnson, Gregory H. Johnson, Stanley G. Love (Ph.D.), Leland D. Melvin, Barbara R. Morgan, William A. Oefelein, John D. Olivas (Ph.D.), Nicholas J.M. Patrick (Ph.D.), Alan G. Poindexter, Garrett E. Reisman (Ph.D.), Steven R. Swanson, Douglas H. Wheelock, Sunita L. Williams, Neil W. Woodward III, George D. Zamka; and the international candidates are Leopold Eyharts, Paolo Nespoli, Hans Schlegel, Roberto Vittori, Bjarni V. Tryggvason, and Marcos Pontes.

  4. 1998 astronaut candidates tour KSC facilities

    NASA Technical Reports Server (NTRS)

    1999-01-01

    On the grounds of the Kennedy Space Center, members of the 1998 astronaut candidate class (Group 17) watch as candidate Tracy E. Caldwell (Ph.D.) practices using firefighting equipment during fire training. The class is at KSC for training activities, including a flight awareness program, plus touring the OPF, VAB, SSPF, SSME Processing Facility, launch pads, SLF, Apollo/Saturn V Center, and the crew quarters. The other U.S. candidates in the '98 class are Clayton C. Anderson, Lee J. Archambault, Gregory E. Chamitoff (Ph.D.), Timothy J. Creamer, Christopher J. Ferguson, Michael J. Foreman, Michael E. Fossum, Kenneth T. Ham, Patricia C. Hilliard (M.D.), Gregory C. Johnson, Gregory H. Johnson, Stanley G. Love (Ph.D.), Leland D. Melvin, Barbara R. Morgan, William A. Oefelein, John D. Olivas (Ph.D.), Nicholas J.M. Patrick (Ph.D.), Alan G. Poindexter, Garrett E. Reisman (Ph.D.), Steven R. Swanson, Douglas H. Wheelock, Sunita L. Williams, Neil W. Woodward III, George D. Zamka; and the international candidates are Leopold Eyharts, Paolo Nespoli, Hans Schlegel, Roberto Vittori, Bjarni V. Tryggvason, and Marcos Pontes.

  5. 1998 astronaut candidates tour KSC facilities

    NASA Technical Reports Server (NTRS)

    1999-01-01

    On the grounds of the Kennedy Space Center, members of the 1998 astronaut candidate class (Group 17) watch as candidate Clayton C. Anderson practices using firefighting equipment during fire training. The class is at KSC for training activities, including a flight awareness program, plus touring the OPF, VAB, SSPF, SSME Processing Facility, launch pads, SLF, Apollo/Saturn V Center, and the crew quarters. The other U.S. candidates in the '98 class are Lee J. Archambault, Tracy E. Caldwell (Ph.D.), Gregory E. Chamitoff (Ph.D.), Timothy J. Creamer, Christopher J. Ferguson, Michael J. Foreman, Michael E. Fossum, Kenneth T. Ham, Patricia C. Hilliard (M.D.), Gregory C. Johnson, Gregory H. Johnson, Stanley G. Love (Ph.D.), Leland D. Melvin, Barbara R. Morgan, William A. Oefelein, John D. Olivas (Ph.D.), Nicholas J.M. Patrick (Ph.D.), Alan G. Poindexter, Garrett E. Reisman (Ph.D.), Steven R. Swanson, Douglas H. Wheelock, Sunita L. Williams, Neil W. Woodward III, George D. Zamka; and the international candidates are Leopold Eyharts, Paolo Nespoli, Hans Schlegel, Roberto Vittori, Bjarni V. Tryggvason, and Marcos Pontes.

  6. 1998 astronaut candidates tour KSC facilities

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Orbiter Processing Facility bay 3, members of the 1998 astronaut candidate class (group 17) get a close-up view of the tiles, part of the thermal protection system, on the underside of the orbiter Atlantis overhead. The class is at KSC for training activities, including fire training and a flight awareness program, plus touring the OPF, SSME Processing Facility, VAB, SSPF, launch pads, SLF, Apollo/Saturn V Center and the crew headquarters. The U.S. candidates in the '98 class are Clayton C. Anderson, Lee J. Archambault, Tracy E. Caldwell (Ph.D.), Gregory E. Chamitoff (Ph.D.), Timothy J. Creamer, Christopher J. Ferguson, Michael J. Foreman, Michael E. Fossum, Kenneth T. Ham, Patricia C. Hilliard (M.D.), Gregory C. Johnson, Gregory H. Johnson, Stanley G. Love (Ph.D.), Leland D. Melvin, Barbara R. Morgan, William A. Oefelein, John D. Olivas (Ph.D.), Nicholas J.M. Patrick (Ph.D.), Alan G. Poindexter, Garrett E. Reisman (Ph.D.), Steven R. Swanson, Douglas H. Wheelock, Sunita L. Williams, Neil W. Woodward III, George D. Zamka; and the international candidates are Leopold Eyharts, Paolo Nespoli, Hans Schlegel, Roberto Vittori, Bjarni V. Tryggvason, and Marcos Pontes.

  7. 1998 astronaut candidates tour KSC facilities

    NASA Technical Reports Server (NTRS)

    1999-01-01

    On the grounds of the Kennedy Space Center, members of the 1998 astronaut candidate class (Group 17) watch as candidate Patricia C. Hilliard (M.D.) practices using firefighting equipment during fire training. The class is at KSC for training activities, including a flight awareness program, plus touring the OPF, VAB, SSPF, SSME Processing Facility, launch pads, SLF, Apollo/Saturn V Center, and the crew quarters. The other U.S. candidates in the '98 class are Clayton C. Anderson, Lee J. Archambault, Tracy E. Caldwell (Ph.D.), Gregory E. Chamitoff (Ph.D.), Timothy J. Creamer, Christopher J. Ferguson, Michael J. Foreman, Michael E. Fossum, Kenneth T. Ham, Gregory C. Johnson, Gregory H. Johnson, Stanley G. Love (Ph.D.), Leland D. Melvin, Barbara R. Morgan, William A. Oefelein, John D. Olivas (Ph.D.), Nicholas J.M. Patrick (Ph.D.), Alan G. Poindexter, Garrett E. Reisman (Ph.D.), Steven R. Swanson, Douglas H. Wheelock, Sunita L. Williams, Neil W. Woodward III, George D. Zamka; and the international candidates are Leopold Eyharts, Paolo Nespoli, Hans Schlegel, Roberto Vittori, Bjarni V. Tryggvason, and Marcos Pontes.

  8. 1998 astronaut candidates tour KSC facilities

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Orbiter Processing Facility, members of the 1998 astronaut candidate class (group 17) learn about the thermal protection system on the orbiters, such as Atlantis overhead. The class is at KSC for training activities, including fire training and a flight awareness program, plus touring the OPF, SSME Processing Facility, VAB, SSPF, launch pads, SLF, Apollo/Saturn V Center and the crew headquarters. The U.S. candidates in the '98 class are Clayton C. Anderson, Lee J. Archambault, Tracy E. Caldwell (Ph.D.), Gregory E. Chamitoff (Ph.D.), Timothy J. Creamer, Christopher J. Ferguson, Michael J. Foreman, Michael E. Fossum, Kenneth T. Ham, Patricia C. Hilliard (M.D.), Gregory C. Johnson, Gregory H. Johnson, Stanley G. Love (Ph.D.), Leland D. Melvin, Barbara R. Morgan, William A. Oefelein, John D. Olivas (Ph.D.), Nicholas J.M. Patrick (Ph.D.), Alan G. Poindexter, Garrett E. Reisman (Ph.D.), Steven R. Swanson, Douglas H. Wheelock, Sunita L. Williams, Neil W. Woodward III, George D. Zamka; and the international candidates are Leopold Eyharts, Paolo Nespoli, Hans Schlegel, Roberto Vittori, Bjarni V. Tryggvason, and Marcos Pontes.

  9. 1998 astronaut candidates tour KSC facilities

    NASA Technical Reports Server (NTRS)

    1999-01-01

    On the grounds of the Kennedy Space Center, members of the 1998 astronaut candidate class (Group 17) watch as candidate Alan G. Poindexter practices using firefighting equipment during fire training. The class is at KSC for training activities, including a flight awareness program, plus touring the OPF, VAB, SSPF, SSME Processing Facility, launch pads, SLF, Apollo/Saturn V Center, and the crew quarters. The other U.S. candidates in the '98 class are Clayton C. Anderson, Lee J. Archambault, Tracy E. Caldwell (Ph.D.), Gregory E. Chamitoff (Ph.D.), Timothy J. Creamer, Christopher J. Ferguson, Michael J. Foreman, Michael E. Fossum, Kenneth T. Ham, Patricia C. Hilliard (M.D.), Gregory C. Johnson, Gregory H. Johnson, Stanley G. Love (Ph.D.), Leland D. Melvin, Barbara R. Morgan, William A. Oefelein, John D. Olivas (Ph.D.), Nicholas J.M. Patrick (Ph.D.), Garrett E. Reisman (Ph.D.), Steven R. Swanson, Douglas H. Wheelock, Sunita L. Williams, Neil W. Woodward III, George D. Zamka; and the international candidates are Leopold Eyharts, Paolo Nespoli, Hans Schlegel, Roberto Vittori, Bjarni V. Tryggvason, and Marcos Pontes.

  10. 1998 astronaut candidates tour KSC facilities

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Space Station Processing Facility (SSPF), members of the 1998 astronaut candidate class (group 17) are shown future components of the International Space Station, such as the Multi- Purpose Logistics Module at right. The class is taking part in training activities, including fire training and a flight awareness program, plus touring the OPF, VAB, SSME Processing Facility, launch pads, SLF, Apollo/Saturn V Center, the crew headquarters, as well as the SSPF. The U.S. candidates in the '98 class are Clayton C. Anderson, Lee J. Archambault, Tracy E. Caldwell (Ph.D.), Gregory E. Chamitoff (Ph.D.), Timothy J. Creamer, Christopher J. Ferguson, Michael J. Foreman, Michael E. Fossum, Kenneth T. Ham, Patricia C. Hilliard (M.D.), Gregory C. Johnson, Gregory H. Johnson, Stanley G. Love (Ph.D.), Leland D. Melvin, Barbara R. Morgan, William A. Oefelein, John D. Olivas (Ph.D.), Nicholas J.M. Patrick (Ph.D.), Alan G. Poindexter, Garrett E. Reisman (Ph.D.), Steven R. Swanson, Douglas H. Wheelock, Sunita L. Williams, Neil W. Woodward III, George D. Zamka; and the international candidates are Leopold Eyharts, Paolo Nespoli, Hans Schlegel, Roberto Vittori, Bjarni V. Tryggvason, and Marcos Pontes.

  11. 1998 astronaut candidates tour KSC facilities

    NASA Technical Reports Server (NTRS)

    1999-01-01

    On the grounds of the Kennedy Space Center, members of the 1998 astronaut candidate class (Group 17) take part in fire training. The class is taking part in training activities, including a flight awareness program, plus touring the OPF, VAB, SSPF, SSME Processing Facility, launch pads, SLF, Apollo/Saturn V Center, and the crew quarters. The U.S. candidates in the '98 class are Clayton C. Anderson, Lee J. Archambault, Tracy E. Caldwell (Ph.D.), Gregory E. Chamitoff (Ph.D.), Timothy J. Creamer, Christopher J. Ferguson, Michael J. Foreman, Michael E. Fossum, Kenneth T. Ham, Patricia C. Hilliard (M.D.), Gregory C. Johnson, Gregory H. Johnson, Stanley G. Love (Ph.D.), Leland D. Melvin, Barbara R. Morgan, William A. Oefelein, John D. Olivas (Ph.D.), Nicholas J.M. Patrick (Ph.D.), Alan G. Poindexter, Garrett E. Reisman (Ph.D.), Steven R. Swanson, Douglas H. Wheelock, Sunita L. Williams, Neil W. Woodward III, George D. Zamka; and the international candidates are Leopold Eyharts, Paolo Nespoli, Hans Schlegel, Roberto Vittori, Bjarni V. Tryggvason, and Marcos Pontes.

  12. 1998 astronaut candidates tour KSC

    NASA Technical Reports Server (NTRS)

    1999-01-01

    At the Apollo/Saturn V Center, some of the 1998 astronaut candidate class (group 17) take a close look at the Saturn V rocket on display. The U.S. candidates include Clayton C. Anderson, Lee J. Archambault, Tracy E. Caldwell (Ph.D.), Gregory E. Chamitoff (Ph.D.), Timothy J. Creamer, Christopher J. Ferguson, Michael J. Foreman, Michael E. Fossum, Kenneth T. Ham, Patricia C. Hilliard (M.D.), Gregory C. Johnson, Gregory H. Johnson, Stanley G. Love (Ph.D.), Leland D. Melvin, Barbara R. Morgan, William A. Oefelein, John D. Olivas (Ph.D.), Nicholas J.M. Patrick (Ph.D.), Alan G. Poindexter, Garrett E. Reisman (Ph.D.), Steven R. Swanson, Douglas H. Wheelock, Sunita L. Williams, Neil W. Woodward III, George D. Zamka; and international candidates Leopold Eyharts, Paolo Nespoli, Hans Schlegel, Roberto Vittori, Bjarni V. Tryggvason, and Marcos Pontes. The class is at KSC for training activities, including fire training and a flight awareness program, plus touring the OPF, SSME Processing Facility, VAB, SSPF, launch pads, SLF, Apollo/Saturn V Center and the crew headquarters.

  13. 1998 astronaut candidates tour KSC

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Some of the 1998 astronaut candidate class (group 17) take a close look at displays in the Apollo/Saturn V Center at KSC. The U.S. candidates include Clayton C. Anderson, Lee J. Archambault, Tracy E. Caldwell (Ph.D.), Gregory E. Chamitoff (Ph.D.), Timothy J. Creamer, Christopher J. Ferguson, Michael J. Foreman, Michael E. Fossum, Kenneth T. Ham, Patricia C. Hilliard (M.D.), Gregory C. Johnson, Gregory H. Johnson, Stanley G. Love (Ph.D.), Leland D. Melvin, Barbara R. Morgan, William A. Oefelein, John D. Olivas (Ph.D.), Nicholas J.M. Patrick (Ph.D.), Alan G. Poindexter, Garrett E. Reisman (Ph.D.), Steven R. Swanson, Douglas H. Wheelock, Sunita L. Williams, Neil W. Woodward III, George D. Zamka; and international candidates Leopold Eyharts, Paolo Nespoli, Hans Schlegel, Roberto Vittori, Bjarni V. Tryggvason, and Marcos Pontes. The class is at KSC for training activities, including fire training and a flight awareness program, plus touring the OPF, SSME Processing Facility, VAB, SSPF, launch pads, SLF, Apollo/Saturn V Center and the crew headquarters.

  14. 1998 astronaut candidates tour KSC facilities

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Orbiter Processing Facility, 1998 astronaut candidates (ASCAN) Barbara R. Morgan, Patricia C. Hilliard (M.D.) and Bjarni V. Tryggvason look at the hardware exhibits, such as the engine actuator on the table. Tryggvason is with the Canadian Space Agency. The 1998 ASCAN class is at KSC for training activities, including fire training and a flight awareness program, plus touring the OPF, SSME Processing Facility, VAB, SSPF, launch pads, SLF, Apollo/Saturn V Center and the crew headquarters. Other U.S. candidates in the '98 class are Clayton C. Anderson, Lee J. Archambault, Tracy E. Caldwell (Ph.D.), Gregory E. Chamitoff (Ph.D.), Timothy J. Creamer, Christopher J. Ferguson, Michael J. Foreman, Michael E. Fossum, Kenneth T. Ham, Gregory C. Johnson, Gregory H. Johnson, Stanley G. Love (Ph.D.), Leland D. Melvin, William A. Oefelein, John D. Olivas (Ph.D.), Nicholas J.M. Patrick (Ph.D.), Alan G. Poindexter, Garrett E. Reisman (Ph.D.), Steven R. Swanson, Douglas H. Wheelock, Sunita L. Williams, Neil W. Woodward III, George D. Zamka; and the other international candidates are Leopold Eyharts, Paolo Nespoli, Hans Schlegel, Roberto Vittori, and Marcos Pontes.

  15. 1998 astronaut candidates tour KSC facilities

    NASA Technical Reports Server (NTRS)

    1999-01-01

    On the grounds of the Kennedy Space Center, members of the 1998 astronaut candidate class (Group 17) watch a demonstration as part of fire training. The class is taking part in training activities, including a flight awareness program, plus touring the OPF, VAB, SSPF, SSME Processing Facility, launch pads, SLF, Apollo/Saturn V Center, and the crew quarters. The U.S. candidates in the '98 class are Clayton C. Anderson, Lee J. Archambault, Tracy E. Caldwell (Ph.D.), Gregory E. Chamitoff (Ph.D.), Timothy J. Creamer, Christopher J. Ferguson, Michael J. Foreman, Michael E. Fossum, Kenneth T. Ham, Patricia C. Hilliard (M.D.), Gregory C. Johnson, Gregory H. Johnson, Stanley G. Love (Ph.D.), Leland D. Melvin, Barbara R. Morgan, William A. Oefelein, John D. Olivas (Ph.D.), Nicholas J.M. Patrick (Ph.D.), Alan G. Poindexter, Garrett E. Reisman (Ph.D.), Steven R. Swanson, Douglas H. Wheelock, Sunita L. Williams, Neil W. Woodward III, George D. Zamka; and the international candidates are Leopold Eyharts, Paolo Nespoli, Hans Schlegel, Roberto Vittori, Bjarni V. Tryggvason, and Marcos Pontes.

  16. 1998 astronaut candidates tour KSC facilities

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Space Station Processing Facility, Ron Woods (left) shows members of the 1998 astronaut candidate class (group 17) an Apollo-style space suit and how it differs from the current suits. The class is taking part in training activities, including fire training and a flight awareness program, plus touring the OPF, VAB, SSPF, launch pads, SLF, Apollo/Saturn V Center, the crew headquarters, as well as the SSME Processing Facility. The U.S. candidates in the '98 class are Clayton C. Anderson, Lee J. Archambault, Tracy E. Caldwell (Ph.D.), Gregory E. Chamitoff (Ph.D.), Timothy J. Creamer, Christopher J. Ferguson, Michael J. Foreman, Michael E. Fossum, Kenneth T. Ham, Patricia C. Hilliard (M.D.), Gregory C. Johnson, Gregory H. Johnson, Stanley G. Love (Ph.D.), Leland D. Melvin, Barbara R. Morgan, William A. Oefelein, John D. Olivas (Ph.D.), Nicholas J.M. Patrick (Ph.D.), Alan G. Poindexter, Garrett E. Reisman (Ph.D.), Steven R. Swanson, Douglas H. Wheelock, Sunita L. Williams, Neil W. Woodward III, George D. Zamka; and the international candidates are Leopold Eyharts, Paolo Nespoli, Hans Schlegel, Roberto Vittori, Bjarni V. Tryggvason, and Marcos Pontes.

  17. 1998 astronaut candidates tour KSC facilities

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Orbiter Processing Facility bay 3, Larry Osheim (right), who is with United Space Alliance, shows members of the 1998 astronaut candidate class (group 17) a sample of Felt Reusable Surface Insulation (FRSI) blankets used on the orbiters. The class is at KSC for training activities, including fire training and a flight awareness program, plus touring the OPF, SSME Processing Facility, VAB, SSPF, launch pads, SLF, Apollo/Saturn V Center and the crew headquarters. The U.S. candidates in the '98 class are Clayton C. Anderson, Lee J. Archambault, Tracy E. Caldwell (Ph.D.), Gregory E. Chamitoff (Ph.D.), Timothy J. Creamer, Christopher J. Ferguson, Michael J. Foreman, Michael E. Fossum, Kenneth T. Ham, Patricia C. Hilliard (M.D.), Gregory C. Johnson, Gregory H. Johnson, Stanley G. Love (Ph.D.), Leland D. Melvin, Barbara R. Morgan, William A. Oefelein, John D. Olivas (Ph.D.), Nicholas J.M. Patrick (Ph.D.), Alan G. Poindexter, Garrett E. Reisman (Ph.D.), Steven R. Swanson, Douglas H. Wheelock, Sunita L. Williams, Neil W. Woodward III, George D. Zamka; and the international candidates are Leopold Eyharts, Paolo Nespoli, Hans Schlegel, Roberto Vittori, Bjarni V. Tryggvason, and Marcos Pontes.

  18. Spin transport at high temperatures in epitaxial Heusler alloy/n-GaAs lateral spin valves

    NASA Astrophysics Data System (ADS)

    Peterson, Timothy A.; Christie, Kevin D.; Patel, Sahil J.; Crowell, Paul A.; Palmstrøm, Chris J.

    2015-03-01

    We report on electrical injection and detection of spin accumulation in ferromagnet/ n-GaAs lateral spin-valve devices, observed up to and above room temperature. The ferromagnet in these measurements is the Heusler alloy Co2FeSi, and the semiconductor channel is GaAs doped at 3 ×1016 cm-3. The spin signal is enhanced by operating the detection contact under forward bias. The enhancement originates from drift effects at low-temperatures and an increase of the detection efficiency at all temperatures. The detector bias dependence of the observed spin-valve signal is interpreted by taking into account the quantum well (QW) which forms in the degenerately doped region immediately behind the Schottky tunnel barrier. In particular, we believe the QW is responsible for the minority spin accumulation (majority spin current) under large forward bias. The spin diffusion length and lifetime are determined by measuring the separation dependence of the non-local spin valve signal in a family of devices patterned by electron beam lithography. A spin diffusion length of 700 nm and lifetime of 46 picoseconds are found at a temperature of 295 K. This work was supported by the NSF under DMR-1104951, the NSF MRSEC program and C-SPIN, a SRC STARNET center sponsored by MARCO and DARPA.

  19. The effect of low-symmetry defects in semiconductors on spin Hall conductivity

    NASA Astrophysics Data System (ADS)

    Mower, Matthew D.; Flatté, Michael E.

    2015-03-01

    We study the effect of low-symmetry defects in semiconductors on the spin Hall conductivity of carriers. It has previously been shown that these defects, e.g. DX centers in direct-gap III-V semiconductors, couple to carriers via a rather large, novel spin-orbit interaction. Compared to translational- or bulk-asymmetry based spin-orbit interactions, this spin-orbit interaction considerably enhances the carrier spin relaxation rate. However, we find that it does not make appreciable contributions to transverse spin currents. At the level of the 1st and 2nd Born approximations, there is neither side-jump nor skew scattering from these defects. Thus, we imagine a scenario where shifting impurities between substitutional and interstitial (low symmetry) positions quickly relaxes a spin system with negligible effects on existing transverse spin currents. This work was supported in part by C-SPIN, one of six centers of STARnet, a Semiconductor Research Corporation program, sponsored by MARCO and DARPA.

  20. Spin Circuit Representation for Spin Pumping Phenomena

    NASA Astrophysics Data System (ADS)

    Roy, Kuntal; Datta, Supriyo

    2015-03-01

    There has been enormous progress in the field of spintronics and nanomagnetics in recent years with the discovery of many new materials and phenomena and it remains a formidable challenge to integrate these phenomena into functional devices and evaluate their potential. To facilitate this process a modular approach has been proposed whereby different phenomena are represented by spin circuit components. Unlike ordinary circuit components, these spin circuit components are characterized by 4-component voltages and currents (one for charge and three for spin). In this talk we will (1) present a spin circuit representation for spin pumping phenomena, (2) combine it with a spin circuit representation for the spin Hall effect to show that it reproduces established results obtained earlier by other means, and finally (3) use it to propose a possible method for enhancing the spin pumping efficiency by an order of magnitude through the addition of a spin sink layer. This work was supported by FAME, one of six centers of STARnet, a Semiconductor Research Corporation program sponsored by MARCO and DARPA.

  1. Detecting spin accumulation in FM/ n-GaAs heterostructures using ferromagnetic resonance

    NASA Astrophysics Data System (ADS)

    Liu, Changjiang; Geppert, Chad; Christie, Kevin; Stecklein, Gordon; Patel, Sahil; Palmstrøm, Chris; Crowell, Paul

    2015-03-01

    A distinguishing feature of spin accumulation in ferromagnet (FM)/semiconductor heterostructures is precession. This is the basis for detection techniques such as the Hanle effect, but these approaches become less effective as the spin lifetime in the semiconductor decreases. We report here on a technique in which the source magnetization is forced to precess at the ferromagnetic resonance frequency, allowing for the detection of spin accumulation even when the spin lifetime is short (less than 100 psec). The samples used in the experiments are MBE-grown FM/(001) n-GaAs heterostructures, in which the FM are the Heusler alloys Co2MnSi and Co2FeSi. These samples show non-local spin valve and Hanle signals in conventional electrical spin injection/detection measurements at low temperatures. Using the FMR technique, we detect the spin accumulation from 30 K to room temperature as a sharp resonance peak. The frequency dependence of the magnitude of the resonance peak allows for a measurement of the spin lifetime. Spin lifetimes as short as 40 psec are measured at room temperature in channels doped at 3x1016cm-3. This work was supported by the NSF under DMR-1104951, the NSF MRSEC program and C-SPIN, a SRC STARNET center sponsored by MARCO and DARPA.

  2. Voltage-controlled magnetic tunnel junctions with Gd2O3 barriers

    NASA Astrophysics Data System (ADS)

    Newhouse-Illige, Ty; Stanford, Charles; Gamble, Matthew; Bi, Chong; Almasi, Hamid; Wang, Weigang

    2015-03-01

    It is of great importance to investigate magnetic tunnel junction (MTJ) with high-k barriers, with the premise that a large voltage-controlled magnetic anisotropy (VCMA) can be achieved due to the increased charge transfer effect. Gd2O3 has a dielectric constant of 22, which is substantially larger than that of MgO (~ 9). It is critical to achieve crystalline barrier with cubic phase in order to obtain symmetry-conserved tunneling as in MgO-based MTJs. We have demonstrated that Cubic Gd2O3 can be grown on amorphous CoFeB by reactive sputtering under proper conditions. In exchanged-biased MTJs with in-plane anisotropy, tunneling magnetoresistance (TMR) up to 12% has been obtained. The sharp switching at near zero field and exchange-bias field higher than 800 Oe indicate the magnetic properties of the CoFeB in these junctions are nearly as good as in MgO-based MTJs. MTJs with interfacial perpendicular magnetic anisotropy (PMA) has been created with TMR ~ 10%. A very interesting VCMA effect in these Gd2O3-based MTJs has been observed and will be discussed. This work was supported in part by NSF (ECCS-1310338) and by C-SPIN, one of six centers of STARnet, a Semiconductor Research Corporation program, sponsored by MARCO and DARPA.

  3. Perpendicular magnetic anisotropy in thin ferromagnetic films adjacent to high-k oxides

    NASA Astrophysics Data System (ADS)

    Xu, Meng; Bi, Chong; Rosales, Marcus; Newhouse-Illige, Ty; Almasi, Hamid; Wang, Weigang

    2015-03-01

    Perpendicular magnetic anisotropy (PMA) in thin ferromagnetic films has attracted a great deal of attention due to interesting physics and promising application in spintronic devices. The strength of PMA is often found to be strongly influenced by the adjacent heavy metal layer and oxide layer. A strong interest has emerged recently to control the PMA of these ultra-thin films by electric fields. Here we report the fabrication and characterization of perpendicularly magnetized 3d transitional metal films next to high-k oxides such as HfO2 and ZrO2. We have investigated structural, magnetic and transport properties of these films. The PMA strongly depends on the thickness of the ferromagnetic layers and the interfacial oxidation level of the bilayers. We will also discuss electric field controlled magnetic properties in these systems. This work was supported in part by NSF (ECCS-1310338) and by C-SPIN, one of six centers of STARnet, a Semiconductor Research Corporation program, sponsored by MARCO and DARPA.

  4. Spin Circuit Model for Spin Orbit Torques in 2D Channels

    NASA Astrophysics Data System (ADS)

    Hong, Seokmin

    2015-03-01

    Recently, the unique coupling between charge and spin in topological insulators has been explored through various types of electrical measurements, which could have interesting applications. In this talk, we present a spin circuit model for spin orbit torques in topological insulator surface states and other 2D channels. We show with a simple example that results from the circuit model agree well with those obtained from nonequilibrium Green's function (NEGF) based quantum transport simulation. Some predictions of our model have already received experimental support and we hope this model can provide a unifying framework that can be used to critically evaluate experimental results, to explore new types of devices as well as to answer fundamental questions regarding these materials. The model for spin-orbit torques described here can be incorporated into a broader spin-circuit approach which, we believe, provides a natural platform for multi-physics, multi-component spintronic devices. This work was supported by FAME, a Semiconductor Research Corporation program sponsored by MARCO and DARPA.

  5. Interfacial Structure in Co2MnSi/GaAs(001) Spin Injection Heterostructures

    NASA Astrophysics Data System (ADS)

    Patel, Sahil; Christie, Kevin; Geppert, Chad; Stecklein, Gordon; Wienkes, Lee; Shi, Fengyuan; Rath, Ashutosh; Schultz, Brian; Mryasov, Oleg; Butler, William; Voyles, Paul; Crowell, Paul; Palmstrom, Christopher; Cspin Collaboration

    2015-03-01

    We report on the role of the interface formation and structure of molecular beam epitaxially grown Co2MnSi/GaAs(001) heterostructures with measured spin accumulations of approximately 60% at 30K in GaAs. In-situ scanning tunneling microscopy (STM) was used to study morphology and x-ray photoelectron spectroscopy (XPS) for the evolution of core level emission peaks as a function of film thickness for thin epitaxial Co2MnSi films. Alternate monolayers of Co and MnSi were deposited to form an epitaxial template layer upon which codeposition of Co, Mn, and Si was used to grow thicker single crystal films. By combining the in-situ XPS elemental layer-by-layer peak evolutions and STM results with ex-situ high angular dark field scanning transmission electron microscopy (HAADF-STEM), x-ray diffraction, SQUID magnetometry and first-principles calculations, consistent models of the growth and interface formation have been developed and will be presented. This work was supported by C-SPIN, one of the six centers of STARnet, a SRC program sponsored by MARCO and DARPA; and by the NSF MRSEC program.

  6. Electrically tunable transport in antiferromagnetic Sr2IrO4

    NASA Astrophysics Data System (ADS)

    Wang, Cheng; Seinige, Heidi; Cao, Gang; Zhou, Jian-Shi; Goodenough, John B.; Tsoi, Maxim

    2015-03-01

    Electronic transport in antiferromagnetic (AFM) Mott insulator Sr2IrO4 is studied under high electric fields. Our goal is to address the question of electronic conduction in nano-scale AFM spintronic applications where high biases and associated electric fields are routinely present. We use nano-scale contacts between a sharpened Cu tip and single crystal of Sr2IrO4 to achieve electric fields up to a few MV/m. When an electrical bias is applied to such a point contact, the electric potential drops essentially in a small contact region, thus leading to high electric fields and providing a means to probe electronic transport on a microscopic scale. Detailed measurements of point-contact current-voltage characteristics revealed that the contact resistance decreased significantly (50-70%) with an increasing dc bias. The observed bias dependence can be well fitted by an activation energy model that involves band structure modifications under strong electric fields. Our findings suggest a promising path towards band-gap engineering in 5d transition metal oxides, which may lead to appealing technical solutions in developing next generation's electronic devices. This work was supported in part by C-SPIN, one of six centers of STARnet, a Semiconductor Research Corporation program, sponsored by MARCO and DARPA, and by NSF Grants DMR-1207577, DMR-1265162 and DMR-1122603.

  7. PVA:LiClO4: a robust, high Tg polymer electrolyte for adjustable ion gating of 2D materials

    NASA Astrophysics Data System (ADS)

    Kinder, Erich; Fullerton, Susan; CenterLow Energy Systems Technology Team

    2015-03-01

    Polymer electrolytes are an effective way to gate organic semiconductors and nanomaterials, such as nanotubes and 2D materials, by establishing an electrostatic double layer with large capacitance. Widely used solid electrolytes, such as those based on polyethylene oxide, have a glass transition temperature below room temperature. This permits relatively fast ion mobility at T = 23 °C, but requires a constant applied field to maintain a doping profile. Moreover, PEO-based electrolytes cannot withstand a variety of solvents, limiting its use. Here, we demonstrate a polymer electrolyte using polyvinyl alcohol (PVA) with Tg >23 °C, through which a doping profile can be defined by a potential applied when the polymer is heated above Tg, then ``locked-in'' by cooling the electrolyte to room temperature (MARCO and DARPA.

  8. Temperature and bias dependence of anisotropic magnetoresistance in antiferromagnetic Sr2IrO4

    NASA Astrophysics Data System (ADS)

    Seinige, Heidi; Wang, Cheng; Cao, Gang; Zhou, Jian-Shi; Goodenough, John B.; Tsoi, Maxim

    2015-03-01

    We study anisotropic magnetoresistance (AMR) in antiferromagnetic (AFM) Mott insulator Sr2IrO4. Such AMR is a promising candidate for monitoring the magnetic order parameter in AFM spintronics. Here we present temperature- and electrical bias-dependent measurements of the point-contact AMR in single crystals of Sr2IrO4. The point-contact technique allows to probe very small volumes and, therefore, look for electronic transport in Sr2IrO4 on a microscopic scale. Point-contact measurements at liquid nitrogen temperature revealed a large negative magnetoresistance (MR) for magnetic fields applied within IrO2 a-b plane and electric currents flowing perpendicular to the plane. The observed MR decreases with increasing temperature and falls to zero at TNéel ~ 240 K. Interestingly, the temperature dependence of MR ratios differs qualitatively from that of the resistivity. The point-contact measurements also show a strong dependence of MR on the dc bias applied to the contact. The latter can be associated with correlations between electronic transport and magnetic order in Sr2IrO4. This work was supported in part by C-SPIN, one of six centers of STARnet, a Semiconductor Research Corporation program, sponsored by MARCO and DARPA, and by NSF Grants DMR-1207577, DMR-1265162 and DMR-1122603.

  9. Density versus spin-density functional in DFT+U and DFT+DMFT

    NASA Astrophysics Data System (ADS)

    Park, Hyowon; Millis, Andrew; Marianetti, Chris

    2015-03-01

    The construction of multi-variable effective action theories such as DFT+U and DFT+DMFT requires the choice of a local subspace of correlated orbitals and an additional variable being either the charge density or spin density. This talk examines the differences between using charge-only and spin-dependent exchange-correlation functionals with the aim of providing guidance for constructing more sophisticated beyond-density functional theories. The widely used spin-dependent approximations to the exchange-correlation functional are found to lead to a large and in some cases unphysical effective exchange coupling within the correlated subspace. Additionally, the differences between Wannier and Projector based definitions of the correlated orbitals are examined, and only small differences are found provided that the orbitals are orthonormal and strongly localized. These results are documented in the context of the rare earth nickelates. This work is supported under the Grant DOE-ER-046169 and under the FAME grant, one of six centers of STARnet, a Semiconductor Research Corporation program sponsored by MARCO and DARPA.

  10. Changing all the rules.

    PubMed

    Imam, H

    1995-01-01

    Princess Nemenzo has been a leader of the struggle for women's rights and political freedom in the Philippines since the 1960s. Despite the recent failures of socialist experiments, she remains committed to a vision of society that minimizes inequalities in the access to and control of economic and social resources. Nemenzo has struggled to apportion her life between her family and her political activism and to survive decades of political persecution and imprisonment. As a researcher at the Ateneo University of Manila, she worked on land reform issues and population policy. While in political exile in Australia, she worked with the international peace movement and contributed to discussions on the impact of development on Third World women. After her return to the Philippines in 1985, Nemenzo became active in the League of Women for Freedom (KALAYAAN), which emerged from the anti-Marcos struggle, and was elected chairperson of the General Assembly Binding Women for Reform, Integrity, Leadership, and Action (GABRIELA). She was influential in persuading KALAYAAN to add reproductive rights as a new dimension to the women's struggle. In 1987, Nemenzo founded Women's Health to promote, defend, and advocate women's reproductive rights and self-determination. The organization addresses reproductive rights within a comprehensive, culturally sensitive women's health framework. PMID:12291841

  11. a Multidisciplinary Approach to the Coastal Protection of Two Archaeological Sites in Lybia

    NASA Astrophysics Data System (ADS)

    D'Urso, I.; Ombrelli, M.; Telaroli, P.; Calesso, W.; Badin, C.; Senigaglia, M.; Urrutia, C.; Sterponi, L.

    2015-04-01

    The present study is part of the preliminary investigation to design a coastal protection for the archaeological sites of Sabratha and Leptis Magna and the hydraulic re-arrangement of the final stretch of the Wadi Lebda which runs across the archaeological area of Leptis Magna. This study is a part of the project "Safeguarding the Sabratha and Leptis Magna archaeological sites. Preventing flooding of Leptis Magna from the Wadi Lebda", started in 2009 and commissioned by MARCO POLO STORICA LTD - Scotland. The planning of interventions has required an accurate morphological reconstruction of the interested areas. In this regard, given the wide investigation area, the aerial and land survey operations logistic difficulties and tight timeframe, the use of multi-beam technology and satellite images was particularly useful. The Digital Terrain Model has been coupled with detailed bathymetric surveys of the coastal area, undertaken mostly by multi-beam techniques, and by investigations of the ground characteristics, which were integrated in the information system prepared as design support.

  12. Application of Vector Spherical Harmonics and Kernel Regression to the Computations of OMM Parameters

    NASA Astrophysics Data System (ADS)

    Marco, F. J.; Martínez, M. J.; López, J. A.

    2015-04-01

    The high quality of Hipparcos data in position, proper motion, and parallax has allowed for studies about stellar kinematics with the aim of achieving a better physical understanding of our galaxy, based on accurate calculus of the Ogorodnikov-Milne model (OMM) parameters. The use of discrete least squares is the most common adjustment method, but it may lead to errors mainly because of the inhomogeneous spatial distribution of the data. We present an example of the instability of this method using the case of a function given by a linear combination of Legendre polynomials. These polynomials are basic in the use of vector spherical harmonics, which have been used to compute the OMM parameters by several authors, such as Makarov & Murphy, Mignard & Klioner, and Vityazev & Tsvetkov. To overcome the former problem, we propose the use of a mixed method (see Marco et al.) that includes the extension of the functions of residuals to any point on the celestial sphere. The goal is to be able to work with continuous variables in the calculation of the coefficients of the vector spherical harmonic developments with stability and efficiency. We apply this mixed procedure to the study of the kinematics of the stars in our Galaxy, employing the Hipparcos velocity field data to obtain the OMM parameters. Previously, we tested the method by perturbing the Vectorial Spherical Harmonics model as well as the velocity vector field.

  13. Tracing the genomic ancestry of Peruvians reveals a major legacy of pre-Columbian ancestors.

    PubMed

    Sandoval, Jose R; Salazar-Granara, Alberto; Acosta, Oscar; Castillo-Herrera, Wilder; Fujita, Ricardo; Pena, Sergio D J; Santos, Fabricio R

    2013-09-01

    In order to investigate the underlying genetic structure and genomic ancestry proportions of Peruvian subpopulations, we analyzed 551 human samples of 25 localities from the Andean, Amazonian, and Coastal regions of Peru with a set of 40 ancestry informative insertion-deletion polymorphisms. Using genotypes of reference populations from different continents for comparison, our analysis indicated that populations from all 25 Peruvian locations had predominantly Amerindian genetic ancestry. Among populations from the Titicaca Lake islands of Taquile, Amantani, Anapia, and Uros, and the Yanque locality from the southern Peruvian Andes, there was no significant proportion of non-autochthonous genomes, indicating that their genetic background is effectively derived from the first settlers of South America. However, the Andean populations from San Marcos, Cajamarca, Characato and Chogo, and coastal populations from Lambayeque and Lima displayed a low but significant European ancestry proportion. Furthermore, Amazonian localities of Pucallpa, Lamas, Chachapoyas, and Andean localities of Ayacucho and Huancayo displayed intermediate levels of non-autochthonous ancestry, mostly from Europe. These results are in close agreement with the documented history of post-Columbian immigrations in Peru and with several reports suggesting a larger effective size of indigenous inhabitants during the formation of the current country's population. PMID:23863748

  14. Editorial: Focus on Extra Space Dimensions

    NASA Astrophysics Data System (ADS)

    Agashe, Kaustubh; Pomarol, Alex

    2010-07-01

    Experiments at the Large Hadron Collider (LHC) have just started. In addition to verifying the Standard Model (SM) of particle physics, these experiments will probe a new energy frontier and test extensions of the SM. The existence of extra dimensions is one of the most attractive possibilities for physics beyond the SM. This focus issue contains a collection of articles addressing both theoretical and phenomenological aspects of extra-dimensional models. Focus on Extra Space Dimensions Contents Minimal universal extra dimensions in CalcHEP/CompHEP AseshKrishna Datta, Kyoungchul Kong and Konstantin T Matchev Disordered extra dimensions Karim Benakli Codimension-2 brane-bulk matching: examples from six and ten dimensions Allan Bayntun, C P Burgess and Leo van Nierop Gauge threshold corrections in warped geometry Kiwoon Choi, Ian-Woo Kim and Chang Sub Shin Holographic methods and gauge-Higgs unification in flat extra dimensions Marco Serone Soft-wall stabilization Joan A Cabrer, Gero von Gersdorff and Mariano Quirós Warped five-dimensional models: phenomenological status and experimental prospects Hooman Davoudiasl, Shrihari Gopalakrishna, Eduardo Pontón and José Santiago

  15. Synthetic fuels, and a sustainable set of civilizations

    SciTech Connect

    Leonard, R.S.

    1996-12-31

    Described in this paper is a concept that combines a set of technologies with a set of economic and social concepts that would allow people to create sustainable ecologies for their region or country. As such it describes a possible implementation path. The technologies are : solar electricity, power satellites, wireless power transmission, electrolytic hydrogen, and synthetic liquid fuels manufactured from air, water, and electricity. Economic initiatives and policies include creating sustainable economic development regions through the use of tax incentives and tax penalties. The technologies and economies are brought together by social concepts such as Technopolis and the theory of self-organizing and self-energizing social systems, i.e. creating wealth where there was none through sweat equity. Existing organizational structures such as credit unions, kibbutz`s and agricultural and marketing cooperatives provide methods by which global marco-projects can be implemented on a local level. Some topics of this paper are : creating global markets by solving global problems or how to breakout of the chicken or egg paradox that has stymied the development of energy from space for so long ; and linking energy availability to self-help economic development programs that create sustainable cultures while benefiting both the local and global environment. 1 refs., 6 figs., 6 tabs.

  16. The Physical Properties of Near-Earth Asteroids Associated With Meteoroid Streams

    NASA Astrophysics Data System (ADS)

    Kelley, Michael; Campins, Humberto; Fernandez, Yan; Jenniskens, Peter; Reach, William; Vaubaillon, Jeremie

    2008-03-01

    The recent Near-Earth asteroid surveys have discovered a number of bodies now identified as parents of our meteor showers. We propose a 7.5 hr Spitzer program to study the physical properties and meteoroid streams of 4 near-Earth asteroids. We will assess the size, albedo, surface composition, and thermal inertia of all 4 targets with 7-14 micron IRS spectra. We also propose MIPS 24 micron maps to measure each targets' meteoroid stream and assess their recent cometary activity. We expect that NEAs associated with meteor showers are all primitive in nature, i.e., they are derived from primitive main belt asteroids, or extinct Jupiter-family comets. We will compare the physical parameters of our targets to NEAs not associated with meteor showers, and to primitive asteroids, in the Spitzer archive. It is important to study NEAs in order to: 1) determine the sources of the current NEA population, 2) characterize the sources of meteorites, meteor showers, and interplanetary dust particles accumulated by the Earth, 3) characterize the properties of Earth impact hazards, and 4) find interesting targets of future robotic and human space exploration missions (e.g., Marco Polo and OSIRIS, two proposed sample return missions). Meteor showers also have a wide public appeal and Spitzer observations of these objects are likely to attract much attention whenever a new call for meteor shower observations is issued to the public.

  17. Recovery of Salmonella from biofilms in a headwater spring ecosystem.

    PubMed

    Gaertner, James P; Mendoza, Joseph A; Forstner, Michael R J; Hahn, Dittmar

    2011-09-01

    Salmonellae are pathogenic bacteria often detected in waters impacted by human or animal wastes. In order to assess the fate of salmonellae in supposedly pristine environments, water and natural biofilm samples along with snails (Tarebia granifera) and crayfish (Procambarus clarkia) were collected before and up to 7 days following four precipitation events from sites within the headwater springs of Spring Lake, San Marcos, TX. The samples were analyzed for the presence of salmonellae by polymerase chain reaction (PCR) after semi-selective enrichment. Salmonellae were detected in one water sample directly after precipitation only, while detection in ten biofilm and two crayfish samples was not related to precipitation. Salmonellae were not detected in snails. Characterization of isolates by rep-PCR revealed shared profiles in water and biofilm samples, biofilm and crayfish samples, and biofilm samples collected 23 days apart. These results suggest that salmonellae are infrequently washed into this aquatic ecosystem during precipitation runoff and can potentially take up residency in biofilms which can help facilitate subsequent long-term persistence and eventual transfer through the food chain. PMID:21976193

  18. An entomological and seroepidemiological study of the vectorial-transmission risk of Chagas disease in the coast of northern Chile.

    PubMed

    González, C R; Reyes, C; Canals, A; Parra, A; Muñoz, X; Rodríguez, K

    2015-12-01

    Four species of triatomines are known from Chile: Triatoma infestans Klug, Mepraia spinolai Porter, M. gajardoi Frías, Henry & González, and M. parapatrica Frías (Hemiptera: Reduviidae), the last three are endemic. The geographical distribution of M. gajardoi includes the coastal areas in the north of Chile between 18° and 21°S, an area with both a resident workforce and summer-season visitors. A study was developed to assess the risk of vectorial transmission of Chagas disease by M. gajardoi in hut settlements on the coast of the Tarapacá Region, in particular in Caleta San Marcos and Caleta Río Seco. The study comprised fingerstick sampling of 95 persons, venous samples from 29 domestic dogs and capture of 52 triatomines, from both fishing coves. The samples were analysed by enzyme-linked immunosorbent assay (ELISA) and polymerase chain reaction (PCR) techniques. The results show that, of the total number of persons studied, 100% were negative for Trypanosoma cruzi Chagas (Trypanosomatida: Trypanosomatidae) antibodies, 10.34% of canids were positive for the antibody and 5.8% of M. gajardoi were infected to the PCR technique. The presence of this species in areas close to human settlements constitutes a risk to human populations established on the coast of northern Chile. PMID:26208149

  19. Salinity variations and chemical compositions of waters in the Frio Formation, Texas Gulf Coast. Annual report

    SciTech Connect

    Morton, R.A.; Garrett, C.M. Jr.; Posey, J.S.; Han, J.H.; Jirik, L.A.

    1981-11-01

    Waters produced from sandstone reservoirs of the deep Frio Formation exhibit spatial variations in chemical composition that roughly coincide with the major tectonic elements (Houston and Rio Grande Embayments, San Marcos Arch) and corresponding depositional systems (Houston and Norias deltas, Greta-Carancahua barrier/strandplain system) that were respectively active along the upper, lower, and middle Texas Coast during Frio deposition. Within an area, salinities are usually depth dependent, and primary trends closely correspond to pore pressure gradients and thermal gradients. Where data are available (mainly in Brazoria County) the increases in TDS and calcium with depth coincide with the zone of albitization, smectite-illite transition, and calcite decrease in shales. Waters have fairly uniform salinities when produced from the same sandstone reservoir within a fault block or adjacent fault blocks with minor displacement. In contrast, stratigraphically equivalent sandstones separated by faults with large displacement usually yield waters with substantially different salinities owing to the markedly different thermal and pressure gradients across the faults that act as barriers to fluid movement.

  20. Geologic framework and hydrogeologic characteristics of the Edwards Aquifer outcrop, Hays County, Texas

    USGS Publications Warehouse

    Hanson, John A.; Small, Ted A.

    1995-01-01

    All of the hydrogeologic subdivisions within the Edwards aquifer outcrop in Hays County have some porosity and permeability. The most porous and permeable appear to be hydrogeologic subdivision VI, the Kirschberg evaporite member of the Kainer Formation; hydrogeologic subdivision III, the leached and collapsed members, undivided; and hydrogeologic subdivision II, the cyclic and marine members, undivided, of the Person Formation. The two types of porosity in the Edwards aquifer outcrop are fabric selective, which is related to depositional or diagenetic elements and typically exists in specific stratigraphic horizons; and not fabric selective, which can exist in any lithostratigraphic horizon. Permeability, the capacity of porous rock to transmit water, depends on the physical properties of the rock such as size, shape, and distribution of pores, and fissuring and dissolution. Two faults, San Marcos Springs and Mustang Branch, completely, or almost completely, offset the Edwards aquifer by juxtaposing Edwards aquifer limestone against nearly impermeable upper confining units along parts of their traces across Hays County. These faults are thought to be barriers, or partial barriers, to ground-water flow where the beds are juxtaposed. In Hays County, the Edwards aquifer probably is most vulnerable to surface contamination in the rapidly urbanizing areas on the Edwards aquifer outcrop. Contamination can result from spills or leakage of hazardous materials; or runoff on the intensely faulted and fractured, karstic limestone outcrops characteristic of the recharge zone.

  1. Acute Exposure to Crystalline Silica Reduces Macrophage Activation in Response to Bacterial Lipoproteins

    PubMed Central

    Beamer, Gillian L.; Seaver, Benjamin P.; Jessop, Forrest; Shepherd, David M.; Beamer, Celine A.

    2016-01-01

    Numerous studies have examined the relationship between alveolar macrophages (AMs) and crystalline silica (SiO2) using in vitro and in vivo immunotoxicity models; however, exactly how exposure to SiO2 alters the functionality of AM and the potential consequences for immunity to respiratory pathogens remains largely unknown. Because recognition and clearance of inhaled particulates and microbes are largely mediated by pattern recognition receptors (PRRs) on the surface of AM, we hypothesized that exposure to SiO2 limits the ability of AM to respond to bacterial challenge by altering PRR expression. Alveolar and bone marrow-derived macrophages downregulate TLR2 expression following acute SiO2 exposure (e.g., 4 h). Interestingly, these responses were dependent on interactions between SiO2 and the class A scavenger receptor CD204, but not MARCO. Furthermore, SiO2 exposure decreased uptake of fluorescently labeled Pam2CSK4 and Pam3CSK4, resulting in reduced secretion of IL-1β, but not IL-6. Collectively, our data suggest that SiO2 exposure alters AM phenotype, which in turn affects their ability to uptake and respond to bacterial lipoproteins. PMID:26913035

  2. The BMW analytic aerodynamic drag method for the Vinti satellite theory

    NASA Technical Reports Server (NTRS)

    Watson, J. S.; Mistretta, G. D.; Bonavito, N. L.

    1972-01-01

    In order to retain separability in the Vinti theory of earth satellite motion when a non conservative force such as air drag is considered, a set of variational equations for the orbital elements are introduced, and expressed as functions of the transverse, radial, and normal components of the nonconservative forces acting on the system. In particular, the atmospheric density profile is written as a fitted exponential function of the eccentric anomaly, which reproduces tabular values of static model atmospheric densities at all altitudes to within ninety-eight percent and simultaneously reduces the variational equations to indefinite integrals with closed form evaluations, whose limits are in terms of the eccentric anomaly. The values of the limits for any arbitrary time interval are obtained from the Vinti program. Results of the BMW (Bonavito, Mistretta, Watson) theory for the case of the intense air drag satellites San Marco-2 and Air Force Cannonball are given. These results indicate that the satellite ephemerides produced by the BMW theory in conjunction with the Vinti program are of very high accuracy. In addition, since the program is entirely analytic, several months of ephemerides can be obtained within a few seconds of computer time.

  3. Angle dependent phonon spectra and thermal properties of misoriented bilayer graphene

    NASA Astrophysics Data System (ADS)

    Neupane, Mahesh; Ramnani, Pankaj; Ge, Supeng; Mulchandani, Ashok; Lake, Roger

    2015-03-01

    The Raman spectra of misoriented bilayer graphene (MBG) show angle dependent signatures of the misorientation angle (?) in the low frequency breathing modes. We investigate these low frequency modes using molecular dynamics including temperature dependent phonon anharmonicity. The calculated vibrational and thermal properties are compared against our experimental data. Our theoretical investigations reveal that the layer breathing mode (LBM) frequencies at 100 +/- 10 cm-1 for angles 6 <= ? <= 30 are consistent with the observed frequencies of ZO modes in the Raman spectrum. For the smaller ? (or larger L), the reduced BZ leads to the zone-folding of the phonon spectrum at the zone center, and leads to broadened optical phonons width in the vibrational density of states. Finally, increasing ? in the MBG leads to a reduction in the lattice specific heat capacity. This work is supported in part by the National Science Foundation (NSF) Grant No: 1307671, and FAME, one of six centers of STARnet, a SRC program sponsored by MARCO and DARPA, and a U.S. Dept. of Education GAANN Fellowship.

  4. Tables of thermospheric temperature, density and composition derived from satellite and ground based measurements. Volume 1: Ap=4

    NASA Technical Reports Server (NTRS)

    Hedin, A. E.

    1979-01-01

    The tables contain the neutral temperature, neutral densities for N2, O2, O, Ar, He and H, mean molecular weight, and total mass density as predicted by the Mass Spectrometer and Incoherent Scatter empirical thermosphere model for selected altitudes, latitudes, local times, days and other geophysical conditions. The model is based on a least squares fit to density data from mass spectrometers on five satellites and temperature data from four incoherent scatter stations, providing coverage for most of solar sunspot cycle 20. Included in the model data base are longitudinally average N3, He, and O densities from the OGO-6 mass spectrometer longitudinally average N2, He, O and Ar densities from the AEROS-A (NATE) mass spectrometer the N2, He, O, and Ar densities from the San Marco 3 mass spectrometer the N2 densities from the AE-B mass spectrometer and the N2, He, O, and Ar densities from the AE-C (OSS, NACE, NATE) mass spectrometers. The O2 and H densities are inferred using ion mass spectrometer data from AE-C (BIMS). Neutral exospheric temperature data are included from Arecibo, St. Santin, Millstone Hill and Jicamarca.

  5. Fish biomarkers for environmental monitoring: An integrated model supporting enzyme activity and histopathological lesions

    NASA Astrophysics Data System (ADS)

    Neta, Raimunda Nonata Fortes Carvalho; Torres Junior, Audalio Rebelo

    2014-10-01

    We present a mathematical model describing the association between glutathione-S-transferase activity and brachial lesions in the catfish, Sciades herzbergii (Ariidae) from a polluted port. The catfish were sampled from a port known to be contaminated with heavy metals and organic compounds and from a natural reserve in São Marcos Bay, Brazil. Two biomarkers, hepatic glutathione S-transferase (GST) activity and histopathological lesions, in gills tissue were measured. The values for GST activity were modeled with the occurrence of branchial lesions by fitting a third order polynomial. Results from the mathematical model indicate that GST activity has a strong polynomial relationship with the occurrence of branchial lesions in both the wet and the dry seasons, but only at the polluted port site. The model developed in this study indicates that branchial and hepatic lesions are initiated when GST activity reaches 2.15 μmol min-1 mg protein-1. Beyond this limit, GST activity decreased to very low levels and irreversible histopathological lesions occurred. This mathematical model provides a realistic approach to analyze predictive biomarkers of environmental health status.

  6. Computer Aided Instruction (CAI) for the Shipboard Nontactical ADP Program (SNAP). Interim report

    SciTech Connect

    Duncan, L.D.; Hammons, C.E.; Hume, R.; Christian, J.; Handler B.H.; Phillips, J.

    1986-01-01

    Oak Ridge National Laboratory is developing a prototype computer aided instruction package for the Navy Management Systems Support Office. This report discusses the background of the project and the progress to date including a description of the software design, problems encountered, solutions found, and recommendations. The objective of this project is to provide a prototype that will enhance training and can be used as a shipboard refresher and retraining tool. The prototype system will be installed onboard ships where Navy personnel will have ready access to the training. The subsequent testing and evaluation of the prototype could provide the basis for a Navy-wide effort to implement computer aided instruction. The work to date has followed a rigorous structured analysis methodology based on the Yourdon/DeMarco techniques. A set of data flow diagrams and a data dictionary are included in the appendices. The problems encountered revolve around requirements to use existing hardware, software, and programmer capabilities for development, implementation, and maintenance of the instructional software. Solutions have been developed which will allow the software to exist in the given environment and still provide advanced features not available in commercial courses.

  7. Unlocking the Past of Sakurai's Object Using FORS/VLT

    NASA Astrophysics Data System (ADS)

    Kerber, F.; Palsa, R.; Köppen, J.; Blöcker, T.; Rosa, M. R.

    2000-09-01

    Sakurai's object (V4334 Sgr) was discovered by Japanese amateur astronomer Y. Sakurai in February 1996 and first classified as a slow nova. Follow-up observations though immediately showed this to be a very special object indeed. It turned out to be a true stellar chameleon, perhaps the most rapidly evolving star ever witnessed. Details of its discovery and early observations are found in Duerbeck et al. (1996, 1997), Kerber et al. (1998) and Clayton & de Marco (1997). We have now used the combined power of FORS/VLT in order to deepen our insight into this object and its evolution. Using FORS/VLT observations, we have obtained the best spectrum of the old PN surrounding Sakurai's object. We have derived improved values for the interstellar reddening and we have been able to reliably measure additional diagnostic lines. In particular, the value found for the He II 4686 line is in excellent agreement with our earlier model calculations. We thereby confirm the previous result that the star was a hot, highly evolved PN nucleus before the flash.

  8. Field Documentation of Unusual Post-Mortem Arthropod Activity on Human Remains.

    PubMed

    Pechal, Jennifer L; Benbow, M Eric; Tomberlin, Jeffery K; Crippen, Tawni L; Tarone, Aaron M; Singh, Baneshwar; Lenhart, Paul A

    2015-01-01

    During a forensic investigation, the presence of physical marks on human remains can influence the interpretation of events related to the death of an individual. Some tissue injury on human remains can be misinterpreted as ante- or peri-mortem wounds by an investigator when in reality the markings resulted from post-mortem arthropod activity. Unusual entomological data were collected during a study examining the decomposition of a set of human remains in San Marcos, Texas. An adult female Pediodectes haldemani (Girard) (Orthoptera: Tettigoniidae) and an Armadillidium cf. vulgare (Isopoda: Armadilidiidae) were documented feeding on the remains. Both arthropods produced physical marks or artifacts on the remains that could be misinterpreted as attack, abuse, neglect, or torture. Additionally, red imported fire ants, Solenopsis invicta Buren (Hymenoptera: Formicidae), were observed constructing structures in the mark produced by the P. haldemani feeding. These observations provide insight into the potential of post-mortem arthropod damage to human remains, which previously had not been described for these taxa, and therefore, physical artifacts on any remains found in similar circumstances may result from arthropod activity and not ante- or peri-mortem wounds. PMID:26336287

  9. Space and Earth Sciences, Computer Systems, and Scientific Data Analysis Support, Volume 1

    NASA Technical Reports Server (NTRS)

    Estes, Ronald H. (Editor)

    1993-01-01

    This Final Progress Report covers the specific technical activities of Hughes STX Corporation for the last contract triannual period of 1 June through 30 Sep. 1993, in support of assigned task activities at Goddard Space Flight Center (GSFC). It also provides a brief summary of work throughout the contract period of performance on each active task. Technical activity is presented in Volume 1, while financial and level-of-effort data is presented in Volume 2. Technical support was provided to all Division and Laboratories of Goddard's Space Sciences and Earth Sciences Directorates. Types of support include: scientific programming, systems programming, computer management, mission planning, scientific investigation, data analysis, data processing, data base creation and maintenance, instrumentation development, and management services. Mission and instruments supported include: ROSAT, Astro-D, BBXRT, XTE, AXAF, GRO, COBE, WIND, UIT, SMM, STIS, HEIDI, DE, URAP, CRRES, Voyagers, ISEE, San Marco, LAGEOS, TOPEX/Poseidon, Pioneer-Venus, Galileo, Cassini, Nimbus-7/TOMS, Meteor-3/TOMS, FIFE, BOREAS, TRMM, AVHRR, and Landsat. Accomplishments include: development of computing programs for mission science and data analysis, supercomputer applications support, computer network support, computational upgrades for data archival and analysis centers, end-to-end management for mission data flow, scientific modeling and results in the fields of space and Earth physics, planning and design of GSFC VO DAAC and VO IMS, fabrication, assembly, and testing of mission instrumentation, and design of mission operations center.

  10. Heme oxygenase-1 in macrophages controls prostate cancer progression.

    PubMed

    Nemeth, Zsuzsanna; Li, Mailin; Csizmadia, Eva; Döme, Balazs; Johansson, Martin; Persson, Jenny Liao; Seth, Pankaj; Otterbein, Leo; Wegiel, Barbara

    2015-10-20

    Innate immune cells strongly influence cancer growth and progression via multiple mechanisms including regulation of epithelial to mesenchymal transition (EMT). In this study, we investigated whether expression of the metabolic gene, heme oxygenase-1 (HO-1) in tumor microenvironment imparts significant effects on prostate cancer progression.We showed that HO-1 is expressed in MARCO-positive macrophages in prostate cancer (PCa) xenografts and human prostate cancers. We demonstrated that macrophage specific (LyzM-Cre) conditional deletion of HO-1 suppressed growth of PC3 xenografts in vivo and delayed progression of prostate intraepithelial neoplasia (PIN) in TRAMP mice. However, initiation and progression of cancer xenografts in the presence of macrophages lacking HO-1 resulted in loss of E-cadherin, a known marker of poor prognosis as well as EMT. Application of CO, a product of HO-1 catalysis, increased levels of E-cadherin in the adherens junctions between cancer cells. We further showed that HO-1-driven expression of E-cadherin in cancer cells cultured in the presence of macrophages is dependent on mitochondrial activity of cancer cells.In summary, these data suggest that HO-1-derived CO from tumor-associated macrophages influences, in part, E-cadherin expression and thus tumor initiation and progression. PMID:26418896

  11. Peruvian Maca: Two Scientific Names Lepidium Meyenii Walpers and Lepidium Peruvianum Chacon – Are They Phytochemically-Synonymous?

    PubMed Central

    Meissner, Henry O.; Mscisz, Alina; Kedzia, Bogdan; Pisulewski, Pawel; Piatkowska, Ewa

    2015-01-01

    Using Liquid Chromatography-Mass Spectrometry (LCMS) , profiles of the two isotypes labelled under the same common name Maca deposited in the Medicinal Plant Herbarium, in Australia and Poland, but identified under two different scientific names Lepidium meyenii Walpers (L. meyenii) and Lepidium peruvianum Chacon (L. peruvianum) are presented. The two isotypes correspond to two holotypes of Peruvian medicinal herb known under the same common name “Maca”, as originally deposited in the Herbarium of San Marcos University in Lima, Peru dated back to 1843 and 1990 respectively. The results demonstrate distinct differences in taxonomy, visual appearance, phytochemical profiles and DNA sequences of the two researched Maca isotypes, suggesting that the two Maca specimens are dissimilar and formal use of the term “synonymous” to L. meyenii and L. peruvianum may be misleading. On the basis of presented results the scientific name L. meyenii, used since 1843 up-today for cultivated Peruvian Maca by numerous reference sources worldwide, including Regulatory Bodies in the USA, EU, Australia and most lately in China, appears to be used in error and should be formally revised. It is concluded, that the isotype of cultivated Peruvian Maca labelled under its scientific name Lepidium peruvianum Chacon, provides all the characteristics peculiar to this historically-documented herb grown in Andean highlands, which may be linked to its traditional use and accepted functionality, confirmed in recent clinical study to be relevant to its present day use for expected dietary, therapeutic and health benefits.

  12. Acute Exposure to Crystalline Silica Reduces Macrophage Activation in Response to Bacterial Lipoproteins.

    PubMed

    Beamer, Gillian L; Seaver, Benjamin P; Jessop, Forrest; Shepherd, David M; Beamer, Celine A

    2016-01-01

    Numerous studies have examined the relationship between alveolar macrophages (AMs) and crystalline silica (SiO2) using in vitro and in vivo immunotoxicity models; however, exactly how exposure to SiO2 alters the functionality of AM and the potential consequences for immunity to respiratory pathogens remains largely unknown. Because recognition and clearance of inhaled particulates and microbes are largely mediated by pattern recognition receptors (PRRs) on the surface of AM, we hypothesized that exposure to SiO2 limits the ability of AM to respond to bacterial challenge by altering PRR expression. Alveolar and bone marrow-derived macrophages downregulate TLR2 expression following acute SiO2 exposure (e.g., 4 h). Interestingly, these responses were dependent on interactions between SiO2 and the class A scavenger receptor CD204, but not MARCO. Furthermore, SiO2 exposure decreased uptake of fluorescently labeled Pam2CSK4 and Pam3CSK4, resulting in reduced secretion of IL-1β, but not IL-6. Collectively, our data suggest that SiO2 exposure alters AM phenotype, which in turn affects their ability to uptake and respond to bacterial lipoproteins. PMID:26913035

  13. PREFACE: XII Latin American workshop on plasma physics (17-21 September 2007, Caracas, Venezuela)

    NASA Astrophysics Data System (ADS)

    Puerta, Julio

    2008-10-01

    Some years ago a group of Latin American physicists took the initiative to consult about the viability of organizing a meeting on plasma physics for researchers and students of the region. The result was that it was not only a good idea, but a necessity in order to show and share everyone's work, and to keep updated on latest advances and technologies on plasma physics. It was decided that for new researchers as well as students of Physics, it would prove to be the best way to keep them posted on such matters. This was the birth of a series of meetings known as Latin American workshops on plasma physics that take place every two years in a different Latin American country. In Venezuela we have had the opportunity to organize two editions of this interesting and important reunion of physicists. The first of these Latin American workshops on plasma physics was held in Cambuquira (Brazil) in 1982. After organizing the first six editions of the workshop, the VII LAWPP meeting was realized in Caracas in January 1997. It was designed with a structure similar to the first edition. It developed in two stages, a first week devoted to short courses with lecturers in different fields of plasma physics and a second week for contributed and invited presentations. Participants from sixteen different countries were present, half of them from this continent and the other half from overseas, demonstrating the international character of this meeting. There have been four more editions of the workshop and once again, we have had the opportunity to organize this latest edition of the series: the XII Latin American workshop on plasma physics, which took place in Caracas, Venezuela from the 17th to the 21st of September 2007. The structure was modified, because contributed and review papers were together during the first stage, with short courses realized during the second one, called mini-courses, and given by several high level contributors such as José Boedo, Leopoldo Soto, Claude Deutsch, Ricardo Galvao, Carlos Hidalgo, Paulo Sakanaka, Konosuke Sato, Malcom Haines and Maher Boulos. The general feeling is that these mini-courses were very successful. As an original idea of Professor Ricardo Magnus Osorio Galvão, Director of Centro Brasileiro de Pesquisas Físicas, we saluted the creation of The Vladimir Tsypin Award to the best Poster in the meeting. This prize was presented by Professor Galvão in memoriam of Vladimir Semenovich Tsypin. It was suggested that the granting of this award be made in every meeting from now on. We think that it is very important to emphasise the mini-courses due to the necessity of increasing in the near future a better formation for our young scientists. The contributions of all the lecturers are greatly appreciated. We had the typical fields in plasma physics as in past meetings. We also appreciated very much the lectures of Professor Malcolm Haines, Professor Sergey Popel, Professor Claude Deutsch, and Professor Antony Peratt for their very interesting talks on the Z-Pinch recorded to prehistory. Special thanks again to these lecturers since they have joined and honoured our meetings in the past as well. As in the VII LAWPP, all the sessions of the workshop were held at the Universidad Simon Bolivar campus, located in the nice green Valley of Sartenejas near Caracas. We also appreciate the stimulus and the financial support that we have always had for the preparation of these workshops from our institution by means of its authorities: Professor Benjamin Sharifker (Rector), Professor Aura Lopez (Dean of Academic Activities), (Professor Jose Luis Paz (Dean of Research and Development), Professor Pedro Berrisbeitia (Dean of Postgraduate Studies) and Professor William Colmenares (Dean of Extended Activities). We must also mention and appreciate the collaboration of architect Alejandro Chataing Roncajolo as Secretary and Coordinator of the Congress, as well as the daily important collaborations of our students Anais Möller, Laura Beiras, Juan Contreras, Gabriel Torrente, Aimée Guerrero, Francisco Jose Blanco Tovar, and last but not least, my son Johann Puerta. Without their generous help and great effort, it would have been impossible for me to organize, reach all the goals and finally, successfully realize the workshop. We are also grateful for the financial support of CLAF (Centro Latino American de Fisica), Fonacit (Fondo Nacional de Ciencia Investigacion y Tecnología), IVIC (Instituto Venezolano de Investigaciones Cientificos), Fundacion Banco Mercantil, whose sponsorship and finnacial support were vital to the realization of the event. We would like to thank La Universidad del Zulia, Universidad Central de Venezuela, Instituto Universitario de Tecnología, IDEA (Instituto de Estudios Avanzados), and Asociación de Amigos de la Universidad Simón Bolivar for their help and support in different ways for the good results we achieved in most of the meetings and the participation of their students who attend the Workshops. Finally we appreciate very much the Ministry for Science and Technology (Ministerio del Poder Popular para la Ciencia y la Tecnología) for their contribution to the workshops and to the publication process. We are under the impression that our meeting was successful, as we expected, and we are thankful for the collaboration of our Institution, and the close relation we had with all the physics researchers of Latin America and abroad (Europe, USA, Australia and Russia). Lastly, many thanks to the invited speakers for their lectures presented which have given a whole overview of the state of the art in different areas of the Physics of Plasma.

  14. The Balloon-borne Large Aperture Submillimeter Telescope: BLAST

    NASA Astrophysics Data System (ADS)

    Truch, Matthew D. P.; Ade, P. A. R.; Bock, J. J.; Chapin, E. L.; Chung, J.; Devlin, M. J.; Dicker, S.; Griffin, M.; Gundersen, J. O.; Halpern, M.; Hargrave, P. C.; Hughes, D. H.; Klein, J.; MacTavish, C. J.; Marsden, G.; Martin, P. G.; Martin, T. G.; Mauskopf, P.; Netterfield, C. B.; Olmi, L.; Pascale, E.; Patanchon, G.; Rex, M.; Scott, D.; Semisch, C.; Thomas, N. E.; Tucker, C.; Tucker, G. S.; Viero, M. P.; Wiebe, D. V.

    2009-01-01

    The Balloon-borne Large Aperture Submillimeter Telescope (BLAST) is a suborbital surveying experiment designed to study the evolutionary history and processes of star formation in local galaxies (including the Milky Way) and galaxies at cosmological distances. The BLAST continuum camera, which consists of 270 detectors distributed between three arrays, observes simultaneously in broadband (30%) spectral windows at 250, 350, and 500 microns. The optical design is based on a 2 m diameter telescope, providing a diffraction-limited resolution of 30" at 250 microns. The gondola pointing system enables raster mapping of arbitrary geometry, with a repeatable positional accuracy of 30"; postflight pointing reconstruction to <5" rms is achieved. The onboard telescope control software permits autonomous execution of a preselected set of maps, with the option of manual override. On this poster, we describe the primary characteristics and measured in-flight performance of BLAST. BLAST performed a test flight in 2003 and has since made two scientifically productive long-duration balloon flights: a 100 hour flight from ESRANGE (Kiruna), Sweden to Victoria Island, northern Canada in 2005 June; and a 250 hour, circumpolar flight from McMurdo Station, Antarctica in 2006 December. The BLAST collaboration acknowledges the support of NASA through grants NAG5-12785, NAG5-13301, and NNGO-6GI11G, the Canadian Space Agency (CSA), the Science and Technology Facilities Council (STFC), Canada's Natural Sciences and Engineering Research Council (NSERC), the Canada Foundation for Innovation, the Ontario Innovation Trust, the Puerto Rico Space Grant Consortium, the Fondo Institucional para la Investigacion of the University of Puerto Rico, and the National Science Foundation Office of Polar Programs.

  15. Mapping opportunities and challenges for rewilding in Europe

    PubMed Central

    Ceaușu, Silvia; Hofmann, Max; Navarro, Laetitia M; Carver, Steve; Verburg, Peter H; Pereira, Henrique M

    2015-01-01

    Farmland abandonment takes place across the world due to socio-economic and ecological drivers. In Europe agricultural and environmental policies aim to prevent abandonment and halt ecological succession. Ecological rewilding has been recently proposed as an alternative strategy. We developed a framework to assess opportunities for rewilding across different dimensions of wilderness in Europe. We mapped artificial light, human accessibility based on transport infrastructure, proportion of harvested primary productivity (i.e., ecosystem productivity appropriated by humans through agriculture or forestry), and deviation from potential natural vegetation in areas projected to be abandoned by 2040. At the continental level, the levels of artificial light were low and the deviation from potential natural vegetation was high in areas of abandonment. The relative importance of wilderness metrics differed regionally and was strongly connected to local environmental and socio-economic contexts. Large areas of projected abandonment were often located in or around Natura 2000 sites. Based on these results, we argue that management should be tailored to restore the aspects of wilderness that are lacking in each region. There are many remaining challenges regarding biodiversity in Europe, but megafauna species are already recovering. To further potentiate large-scale rewilding, Natura 2000 management would need to incorporate rewilding approaches. Our framework can be applied to assessing rewilding opportunities and challenges in other world regions, and our results could guide redirection of subsidies to manage social-ecological systems. Mapeo de Oportunidades y Retos para el Retorno de la Vida Silvestre Resumen El abandono de tierras agrícolas ocurre en todo el mundo debido a factores socio-económicos y ecológicos. En Europa, las políticas ambientales y agrícolas tienen el objetivo de prevenir el abandono y frenar la sucesión ecológica. La reintroducción o el retorno de la vida silvestre (“rewilding”) representa una estrategia alternativa a esto. Desarrollamos un marco de trabajo para evaluar las oportunidades de reintroducción en diferentes dimensiones de naturaleza a lo largo de Europa. Mapeamos la luz artificial, la accesibilidad para humanos con base en la infraestructura de transporte, la proporción de productividad primaria (es decir, la productividad del ecosistema incautado por los humanos por medio de la agricultura o la silvicultura) y la divergencia de vegetación natural potencial en áreas que se proyecta estarán abandonadas para el 2040. A nivel continental, los niveles de luz artificial fueron bajos y la divergencia de vegetación natural potencial fue alta en las áreas de abandono. La importancia relativa de las medidas de naturaleza difirió regionalmente y estuvieron conectadas fuertemente a los contextos ambientales y socio-económicos locales. Las grandes áreas de abandono proyectado estuvieron localizadas frecuentemente en o alrededor de sitios Natura 2000. Con base en estos resultados, argumentamos que el manejo debería ser fabricado para restaurar los aspectos de la naturaleza que son carentes en cada región. Todavía quedan muchos obstáculos con respecto a la biodiversidad en Europa, pero las especies de megafauna ya se están recuperando. Para potenciar aún más la reintroducción a gran escala, el manejo de Natura 2000 necesitaría incorporar estrategias de reintroducción. Nuestro marco de trabajo puede aplicarse a la evaluación de las oportunidades de reintroducción y a los obstáculos en otras regiones del mundo, y nuestros resultados pueden guiar la redirección de los subsidios para manejar los sistemas socio-ecológicos. PMID:25997361

  16. Updated numerical model with uncertainty assessment of 1950-56 drought conditions on brackish-water movement within the Edwards aquifer, San Antonio, Texas

    USGS Publications Warehouse

    Brakefield, Linzy K.; White, Jeremy T.; Houston, Natalie A.; Thomas, Jonathan V.

    2015-01-01

    In 2010, the U.S. Geological Survey, in cooperation with the San Antonio Water System, began a study to assess the brackish-water movement within the Edwards aquifer (more specifically the potential for brackish-water encroachment into wells near the interface between the freshwater and brackish-water transition zones, referred to in this report as the transition-zone interface) and effects on spring discharge at Comal and San Marcos Springs under drought conditions using a numerical model. The quantitative targets of this study are to predict the effects of higher-than-average groundwater withdrawals from wells and drought-of-record rainfall conditions of 1950–56 on (1) dissolved-solids concentration changes at production wells near the transition-zone interface, (2) total spring discharge at Comal and San Marcos Springs, and (3) the groundwater head (head) at Bexar County index well J-17. The predictions of interest, and the parameters implemented into the model, were evaluated to quantify their uncertainty so the results of the predictions could be presented in terms of a 95-percent credible interval. The model area covers the San Antonio and Barton Springs segments of the Edwards aquifer; the history-matching effort was focused on the San Antonio segment. A previously developed diffuse-flow model of the Edwards aquifer, which forms the basis for the model in this assessment, is primarily based on a conceptualization in which flow in the aquifer is predominately through a network of numerous small fractures and openings. Primary updates to this model include an extension of the active area downdip, a conversion to an 8-layer SEAWAT variable-density flow and transport model to simulate dissolved-solids concentration effects on water density, history matching to 1999–2009 conditions, and parameter estimation in a highly parameterized context using automated methods in PEST (a model-independent Parameter ESTimation code). In addition to the best-fit parameter values derived from history matching, the uncertainty of model parameters was also estimated by using linear uncertainty analysis. Comparison of “prior” (before history matching) and “posterior” (after history matching) variances of parameters indicate that the information within the observation dataset used for history matching informs many parameters. The concentration threshold parameters were well-informed by the observation dataset as their posterior distributions were much narrower than their prior distributions. The transition-zone scaling parameters of hydraulic conductivity, effective porosity, and specific storage were all informed by the observation dataset, as evidenced by the difference between the prior and posterior variances. Saline-zone scaling parameters, alternatively, were not informed by the observation dataset for effective porosity and specific storage. Resulting posterior drier-month, wetter-month, and annual recharge multiplier parameter variances are important to understanding how well recharge is estimated and implemented within the model. The shifts of the posterior distributions left and right indicate that there were zones where less or more water was needed in the model. The widths of the distributions were not decreased substantially, indicating that many of the best-fit recharge parameters are not statistically different from the initial values specified in the history-matching effort. Recharge from rainfall is the driving force behind groundwater flow and heads in the aquifer; therefore, an increase in understanding of this process would benefit model development by potentially decreasing the uncertainty of this parameter. The history-matching effort was most helpful in informing the parameters in the model that control discharge at springs, namely, the spring orifice (drain) altitude and drain conductance parameters for each spring. The uncertainty assessment of the predictive model (a hypothetical recu

  17. Are regional projections of extreme sea levels based on uncertain future MSL scenarios reliable? A case study for the south-eastern North Sea

    NASA Astrophysics Data System (ADS)

    Dangendorf, S.; Mudersbach, C.; Jensen, J.

    2012-12-01

    Recently a number of authors applied a method (offset method) to combine observations of present sea level extremes with projections of future sea level rise during the 21st century. The method provides a technique for estimating potential future exceedence probabilities based on the assumption that both variability and trends of extreme sea levels have been and will be driven by changes in MSL. This assumption has been confirmed for quasi-global (Woodworth et al. 2011) and regional data-sets (Marcos et al. 2009). However, if the assumption fails, the application of the method will result in large inaccuracies. In the present study, records from 13 tide gauges located in the German Bight, a part of the south-eastern North Sea, are investigated. Time series of extreme high sea levels, covering a period from 1900 to 2008, are analyzed relative to simultaneous changes in MSL. For that purpose in a first step only extreme sea levels have been analyzed, while in a second step MSL time series have been subtracted from the extremes to prove the evidence of trend and variability differences. The results point to a significantly stronger increase in extreme sea levels during the second half of the 20th century. While in the first half of the 20th century the evolution of extreme sea levels follows changes in MSL, in the second half a significant rise with values between 10 and 60 cm per century relative to the MSL has been observed. The divergent development varies seasonally. The largest deviations between extreme sea levels and the MSL have been detected during Season 1 [January to March], while considerably smaller but statistically significant changes have been observed during the remaining seasons. An investigation of reanalyzed datasets from the 20th century reanalysis project (20thCR) shows that large parts of the observed deviations are in phase with simultaneous changes in the local zonal extreme wind conditions and only small deviations remain. Using the above mentioned observations, a statistical model is introduced to reconstruct observed changes in extreme sea levels based on MSL and extreme zonal winds. Depending on the investigated season, these models are able to explain between ~46 and ~80% of the observed variability and between ~80 and ~100% of the observed long-term trends. Hence, to account for potential future changes in the local wind regime when estimating future sea level extremes, an extended technique should include both (uncertain) sea level rise and storminess. Regarding the main question of this study, the results therefore show that the offset method is not suitable for the application to tide gauges located in the German Bight. References: Marcos M, Tsimplis M (2009): Sea level extremes in southern Europe, J Geoph Res, Vol. 114, C01007, 16 PP. Woodworth PL, Menéndez M, Gehrels WR (2011): Evidence for Century-Timescale Acceleration in Mean Sea Levels and for Recent Changes in Extreme Sea Levels, Surv Geophys 32:603-618

  18. Broken formations, melanges and olistostromes in Puerto Plata area (Northern Dominican Republic) as a record of subduction and collisional processes between the Caribbean and North-American plates

    NASA Astrophysics Data System (ADS)

    Hernaiz Huerta, Pedro Pablo; Valera Fernando, Pérez; de Los Santos Manuel, Abad; Jacques, Monthel; de Neira Alberto, Díaz

    2010-05-01

    The Northern Cordillera of the Dominican Republic records the (oblique) subduction and collisional processes occurred between the Caribbean and North-American plates during Upper Cretaceous to Lower Paleogene times. The boundary between these two plates can be traced within this range disrupted by an Upper Paleogene to present intense left-lateral strike-slip tectonism, onset after collision. In the western part of the range this boundary might be defined by the Camu fault. In the coastal area of Puerto Plata, located on the northern block of the Camu fault, basement rocks belonging to the subducting plate (the Puerto Plata Basement Complex) and several related units probably formed in an accretionary prism, preserve in a large (300 km2) outcrop of chaotic formations presumably formed (and exhumed) during collision. They include from broken formations and tectonic melanges to olistostromes and other coeval sedimentary deposits. The Puerto Plata Basement Complex (PPBC) consists of highly faulted and dismembered blocks formed by discontinuous but sometimes coherent outcrops of serpentinized or massive peridotite, pods of ultramafic cumulates, massive or banded gabbros and Los Caños Fm, a thick sequence of gross bedded volcaniclastic material with interbedded basaltic (sometimes pillowed) or andesitic flows. All these rocks bear low grade metamorphism and lack a general deformation fabric apart from occasional transformation to mylonites due to localized shearing. The PPBC has been interpreted as a fragment of oceanic crust, belonging to the subducting (North-American) slab that has been exhumed as a tectonic melange or a broken complex. The Imbert Fm, of Palaeocene-Eocene age, is formed by a well bedded succession of white very fine grained porcelaneous tuffs, with eventual intercalations of cherts, limestones and marls that, towards the lower part, is interbedded with volcanic-derived graywackes and limolites, and more occasionally, thick beds of conglomerates and debris. These last ones typically incorporate fragments of serpentized peridotites and blocks of the volcanic rocks identified in the PPBC. The Imbert Fm is also internally disrupted and although not a single clear contact can be observed in the field, it is considered to rest unconformably over the complex, so postdating its exhumation. A separate mappable unit of serpentinitic brecchias has recently been identified mainly distributed along the outer limits of the PPBC but also in several scattered outcrops inside it. The unit is dominantly made of fragments and blocks of serpentinized peridotites, embedded in an abundant matrix of the same composition and includes also blocks of Los Caños and Imbert Fm, as well as other exotic blocks of unknown origin. In the southeastern limit of the complex, close to the Camu fault, there is a particular high concentration of exotic blocks derived from metamorphic rocks (greenschists, anfibolites, marbles and even blueschists) not exposed in any neighbouring areas and thus suggesting a deep-sited, subduction-related, feeding. The basal contact of this unit with the rocks of the PPBC is usually faulted and difficult to observe in the field, but cartographic patterns suggest that it is an unconformity. Outcrops of serpentinitic breccias show a wide variety of internal chaotic organization, from pods of tectonic melanges to the most frequent block-in matrix fabric, but most of them also show evidences of sedimentary rework. In the easternmost part of the PPBC, the serpentinitic brecchias are, in turn, the base of an olistostromic complex widely represented in the region, the San Marcos Fm. The olistostrome includes similar exotic blocks than observed in the serpentinitic brecchias and blocks and olistolithes derived from the PPBC but, mainly, from the Imbert Fm. According to the described relationships, the serpentinitic breccias and San Marcos olistostrome are considered partially coeval and laterally equivalent to the Imbert Fm.

  19. Preliminary investigation of the nature and origin of the Sierra Mojada Non-sulfide Zn deposits, Coahuila, Mexico

    NASA Astrophysics Data System (ADS)

    Ahn, H.; Kyle, J.; Gilg, H.; Kolvoord, R.

    2009-05-01

    The Sierra Mojada district consists of multiple types of mineral concentrations ranging from polymetallic sulfide deposits, 'non-sulfide Zn' deposits (separate smithsonite and hemimorphite zones), and a Pb carbonate manto hosted by Upper Jurassic to Lower Cretaceous carbonates. The district is typically grouped with other polymetallic carbonate replacement deposits of southwestern North America, but the intrusive rocks that commonly are associated with these types of deposits are not known at Sierra Mojada. The Sierra Mojada district located near the boundary of the Coahuila Platform and the Sabinas Basin that formed during Late Jurassic and Cretaceous tectonic extension. The east-trending San Marcos fault runs through the Sierra Mojada district and is thought to have acted as the major conduit for basinal fluids, responsible for local dolomitization, sulfide mineralization, and petroleum in the region. The polymetallic sulfides are the stratigraphically and structurally highest ore zone and occur north of the San Marcos fault. Non-sulfide Zn (hemimorphite, smithsonite and sauconite) and lead (cerussite) concentrations occur south of the fault in the Aurora and La Pena Formations. The Iron Oxide Manto consists of stratabound zones of dominantly of hemimorphite pore-filling in Fe-oxide rich dolostones giving the ore a distinct red to orange color. The Smithsonite Manto has distinct karst features, including internal sediments interbanded with smithsonite in the lower part of the orebody. The non-sulfide Zn ores are being studied to document their morphologies, growth patterns, and paragenetic relationships using conventional petrography, SEM, and CL-based ESEM. In the Smithsonite Manto, banded and colloform smithsonite consists of aggregates of rhombohedral crystals that grew into open space and also occurs within internal sediment bands with hemimorphite or Zn clays and Zn oxides. Black dendrites of Mn oxides with Fe oxides are encased in banded smithsonite. Euhedral hemimorphite is present in both mantos, although it is most abundant in the Iron Oxide Manto. Hemimorphite occurs in the Smithsonite Manto as layers with smithsonite suggesting that they may have precipitated together, although locally hemimorphite cross-cuts smithsonite bands. Locally, hemimorphite and smithsonite have been altered to sauconite and hydrozincite. Associated minerals include barite and calcite that seem to have formed later than the major Zn mineral formation. Preliminary isotope studies reveal that smithsonites from Sierra Mojada have ?18OVSMOW values ranging from 19.1 to 22.1 and ?13CVPDB values of -7.0 to +1.0 . While the range of carbon isotope values is typical for supergene smithsonites, the oxygen isotope values are much lower than those recorded in most supergene deposits. The unusually low oxygen isotope values in smithsonite require either highly 18O- depleted waters of less than -12 if oxidation occurred at temperatures of less than 20C or elevated temperatures (>40C) during oxidation if waters had isotope compositions similar to present- day ground waters in the area. Studies are in progress to further constrain the paragenesis, mineralizing fluid character, and timing of mineralization in the Sierra Mojada district.

  20. Soft-sediment mullions

    NASA Astrophysics Data System (ADS)

    Ortner, Hugo

    2015-04-01

    In this contribution I describe the appearance, formation and significance of soft-sediment mullions. I use several examples from synorogenic turbidites of the Alps and the Pyrenees to show their appearance in the field. Soft-sediment mullions are elongate, slightly irregular bulges at the base of coarse-grained clastic beds (sand to conglomerate), separated by narrow, elongate flames of fine-grained material (mud) protruding into the coarse-grained bed. Various processes may lead to the formation of such structures: (1) longitudinal furrows parallel to the sediment transport direction may form by spiral motion in flow rolls during sediment transport (Dzulinski, 1966; Dzulinski & Simpson, 1966). (2) Loading combined with downslope movement can produce elongate structures parallelling the dowslope direction (Anketell et al., 1970). (3) Soft-sediment mullions are oriented perpendicular or oblique to the downslope direction, and show evidence of bedding-parallel shortening. Thus, they resemble cuspate-lobate folds or mullions, which are well-known in ductile structural geology (e.g. Urai et al., 2001). Soft-sediment mullions have been observed in two cases: Either bedding-parallel shortening can be achieved by slump processes, or by active tectonic shortening. Slumping is characterized by an alternation of stretching and shortening (e.g. Ortner, 2007; Alsop & Marco 2014), and therefore mullions do overprint or are overprinted by normal faults. In active depositional systems that are subject to tectonic shortening growth strata will form, but sediments already deposited will be shortened during lithification. In some cases, the formation of soft-sediment mullions predates folding, but the most widespread expression of syn-lithification shortening seems to be soft-sediment mullions, that form in the inner arcs of fold hinges. In the examples documented so far, the size of soft-sediment mullions is dependent on the grain-size of the coarse-grained layer, in which the mullions form. In coarse conglomerates, meter-scale mullions were observed, in sandstones centimeter-scale mullions. There does not seem to exist a relationship to the rate of shortening, as the size of mullions is independent of their position in larger scale folds, or in slump complexes or tectonic folds. Anketell, J.M., Cegla, J. & Dzulynsky, S. (1970): On the deformational structures in systems with reversed density gradients. Ann. Soc. Geol. Pol., 40(1): 3-30. Alsop, G.I., Marco, S., 2014. Fold and fabric relationships in temporally and spatially evolving slump systems: A multi-cell flow model. Jour. Struct. Geol., 63(0): 27-49. Dzulynsky, S. (1966): Sedimentary structures resulting from convection-like pattern of motion. Ann. Soc. Geol. Pol., 36(1): 3-21. Dzulinsky, S. & Simpson, F. (1966): Experiments on interfacial current markings. Geol. Rom., 5: 197 - 214. Ortner, H. (2007): Styles of soft-sediment deformation on top of a growing fold system in the Gosau Group at Muttekopf, Northern Calcareous Alps, Austria: Slumping versus tectonic deformation. Sed. Geol., 196: 99-118. Urai, J.L., Spaeth, G., Van der Zee, W. & Hilger, C. (2001): Evolution of mullion (boudin) structures in the Variscan of the Ardennes and Eifel. Jour. Virt. Expl., 3: 1-16.

  1. EDITORIAL: Focus on Dark Matter and Particle Physics

    NASA Astrophysics Data System (ADS)

    Aprile, Elena; Profumo, Stefano

    2009-10-01

    The quest for the nature of dark matter has reached a historical point in time, with several different and complementary experiments on the verge of conclusively exploring large portions of the parameter space of the most theoretically compelling particle dark matter models. This focus issue on dark matter and particle physics brings together a broad selection of invited articles from the leading experimental and theoretical groups in the field. The leitmotif of the collection is the need for a multi-faceted search strategy that includes complementary experimental and theoretical techniques with the common goal of a sound understanding of the fundamental particle physical nature of dark matter. These include theoretical modelling, high-energy colliders and direct and indirect searches. We are confident that the works collected here present the state of the art of this rapidly changing field and will be of interest to both experts in the topic of dark matter as well as to those new to this exciting field. Focus on Dark Matter and Particle Physics Contents DARK MATTER AND ASTROPHYSICS Scintillator-based detectors for dark matter searches I S K Kim, H J Kim and Y D Kim Cosmology: small-scale issues Joel R Primack Big Bang nucleosynthesis and particle dark matter Karsten Jedamzik and Maxim Pospelov Particle models and the small-scale structure of dark matter Torsten Bringmann DARK MATTER AND COLLIDERS Dark matter in the MSSM R C Cotta, J S Gainer, J L Hewett and T G Rizzo The role of an e+e- linear collider in the study of cosmic dark matter M Battaglia Collider, direct and indirect detection of supersymmetric dark matter Howard Baer, Eun-Kyung Park and Xerxes Tata INDIRECT PARTICLE DARK MATTER SEARCHES:EXPERIMENTS PAMELA and indirect dark matter searches M Boezio et al An indirect search for dark matter using antideuterons: the GAPS experiment C J Hailey Perspectives for indirect dark matter search with AMS-2 using cosmic-ray electrons and positrons B Beischer, P von Doetinchem, H Gast, T Kirn and S Schael Axion searches with helioscopes and astrophysical signatures for axion(-like) particles K Zioutas, M Tsagri, Y Semertzidis, T Papaevangelou, T Dafni and V Anastassopoulos The indirect search for dark matter with IceCube Francis Halzen and Dan Hooper DIRECT DARK MATTER SEARCHES:EXPERIMENTS Gaseous dark matter detectors G Sciolla and C J Martoff Search for dark matter with CRESST Rafael F Lang and Wolfgang Seidel DIRECT AND INDIRECT PARTICLE DARK MATTER SEARCHES:THEORY Dark matter annihilation around intermediate mass black holes: an update Gianfranco Bertone, Mattia Fornasa, Marco Taoso and Andrew R Zentner Update on the direct detection of dark matter in MSSM models with non-universal Higgs masses John Ellis, Keith A Olive and Pearl Sandick Dark stars: a new study of the first stars in the Universe Katherine Freese, Peter Bodenheimer, Paolo Gondolo and Douglas Spolyar Determining the mass of dark matter particles with direct detection experiments Chung-Lin Shan The detection of subsolar mass dark matter halos Savvas M Koushiappas Neutrino coherent scattering rates at direct dark matter detectors Louis E Strigari Gamma rays from dark matter annihilation in the central region of the Galaxy Pasquale Dario Serpico and Dan Hooper DARK MATTER MODELS The dark matter interpretation of the 511 keV line Céline Boehm Axions as dark matter particles Leanne D Duffy and Karl van Bibber Sterile neutrinos Alexander Kusenko Dark matter candidates Lars Bergström Minimal dark matter: model and results Marco Cirelli and Alessandro Strumia Shedding light on the dark sector with direct WIMP production Partha Konar, Kyoungchul Kong, Konstantin T Matchev and Maxim Perelstein Axinos as dark matter particles Laura Covi and Jihn E Kim

  2. PREFACE: 3rd Workshop on Theory, Modelling and Computational Methods for Semiconductors (TMCSIII)

    NASA Astrophysics Data System (ADS)

    Califano, Marco; Migliorato, Max; Probert, Matt

    2012-05-01

    These conference proceedings contain the written papers of the contributions presented at the 3rd International Conference on Theory, Modelling and Computational Methods for Semiconductor materials and nanostructures. The conference was held at the School of Electronic and Electrical Engineering, University of Leeds, Leeds, UK on 18-20 January 2012. The previous conferences in this series took place in 2010 at St William's College, York and in 2008 at the University of Manchester, UK. The development of high-speed computer architectures is finally allowing the routine use of accurate methods for calculating the structural, thermodynamic, vibrational, optical and electronic properties of semiconductors and their hetero- and nano-structures. The scope of this conference embraces modelling, theory and the use of sophisticated computational tools in semiconductor science and technology, where there is substantial potential for time-saving in R&D. Theoretical approaches represented in this meeting included: Density Functional Theory, Tight Binding, Semiempirical Pseudopotential Methods, Effective Mass Models, Empirical Potential Methods and Multiscale Approaches. Topics included, but were not limited to: Optical and Transport Properties of Quantum Nanostructures including Colloids and Nanotubes, Plasmonics, Magnetic Semiconductors, Graphene, Lasers, Photonic Structures, Photovoltaic and Electronic Devices. This workshop ran for three days, with the objective of bringing together UK and international leading experts in the theoretical modelling of Group IV, III-V and II-VI semiconductors, as well as students, postdocs and early-career researchers. The first day focused on providing an introduction and overview of this vast field, aimed particularly at students, with several lectures given by recognised experts in various theoretical approaches. The following two days showcased some of the best theoretical research carried out in the UK in this field, with several contributions also from representatives of renowned theoretical groups from many European countries (Spain, France, Ireland, Germany, Italy, Poland, Denmark, Sweden, Serbia, Greece, etc.), as well as Asia (India) and Africa (Algeria, Tunisia and South Africa). We would like to thank all participants for making this a very successful meeting and for their contribution to the conference programme and these proceedings. We would also like to acknowledge the financial support from the Institute of Physics (Computational Physics group and Semiconductor Physics group), and QuantumWise (distributors of Atomistix). The Editors Acknowledgments Conference Organising Committee: Marco Califano (University of Leeds) Max Migliorato (University of Manchester) Matt Probert (University of York) Programme Committee: Stewart Clark (University of Durham) Aldo Di Carlo (University of Rome 'Tor Vergata', Italy) Ben Hourahine (University of Strathclyde) Lev Kantorovich (King's College London) Risto Nieminen (Helsinki University of Technology, Finland) Eoin O'Reilly (Tyndall Institute Cork, Republic of Ireland) Mauro Pereira (Sheffield Hallam University) John Robertson (University of Cambridge) Mervin Roy (University of Leicester) Stanko Tomic (University of Salford) David Whittaker (University of Sheffield) The proceedings were edited and compiled by Marco Califano, Max Migliorato and Matt Probert.

  3. Gene expression differences in adipose tissue associated with breast tumorigenesis

    PubMed Central

    Sturtz, Lori A; Deyarmin, Brenda; van Laar, Ryan; Yarina, William; Shriver, Craig D; Ellsworth, Rachel E

    2014-01-01

    Long thought to function only as an inert energy storage depot, the role of adipose tissue in breast tumorigenesis has been largely ignored. In light of increasing rates of obesity and use of breast conserving therapy and autologous fat grafting, improved understanding of the role of adipose tissue in tumor etiology is crucial. Thus, adipose tissue adjacent to and distant from invasive breast tumors (n = 20), or adjacent to non-malignant diagnoses (n = 20) was laser microdissected from post-menopausal women. Gene expression data were generated using microarrays and data analyzed to identify significant patterns of differential expression between adipose tissue groups at the individual gene and molecular pathway level. Pathway analysis revealed significant differences in immune response between non-malignant, distant, and tumor-adjacent adipose tissue, with the highest response in tumor-adjacent and lowest in non-malignant adipose tissue. Adipose tissue from invasive breasts exhibits increased expression of anti-inflammatory genes such as MARCO and VSIG4 while genes differentially expressed between tumor-adjacent and distant adipose tissue such as SPP1, RRM2, and MMP9, are associated with increased cellular proliferation, invasion, and angiogenesis. These data suggest that molecular profiles of adipose tissue differ depending on presence of or proximity to tumor cells. Heightened immunotolerance in adipose tissue from invasive breasts provides a microenvironment favorable to tumorigenesis. In addition, tumor-adjacent adipose tissue demonstrates expression of genes associated with tumor growth and progression. Thus, adipose tissue is not an inert component of the breast microenvironment but plays an active role in tumorigenesis. PMID:24719783

  4. The (cQ)2 collaboration: assessing watershed scale hydrological changes for the province of Québec at the 2050 horizon

    NASA Astrophysics Data System (ADS)

    Guay, Catherine; Minville, Marie

    2013-04-01

    The (cQ)2 project is a collaboration of various managers of water resources in Québec. This joint effort aims at sharing best practices in hydrological impact studies in order to deliver a concerted message about the potential impact of climate change on Québec hydrology. The project brings together key actors of the hydrological field and climate research: Hydro-Québec, the provincial hydro-power company; the Centre d'expertise hydrique du Québec, a governmental agency accountable for provincial water management in terms of safety, equity and sustainability; Rio Tinto Alcan, an aluminium producer who also owns power-houses on Québec rivers; and Ouranos, a regional consortium on climatology and adaptation to climate change. We provide an overview of the study framework adopted in the first phase of the project which includes the use of a large climatic ensemble based on simulations from global and regional climate models, different emission scenarios, and multiple post-processing methods. This ensemble is further described in a presentation by Marco Braun1. The hydrological simulations are carried out using HSAMI, a lumped and conceptual model, applied to over 300 Québec river basins; and HYDROTEL, a distributed and physically-based hydrological model used for 40 watersheds of southern Québec. As an outcome to this study, the expected change in hydrological variables such as floods and droughts, seasonal flow, evapotranspiration, and snow water equivalent, is presented. The change in those variables is critical for mid-term and long-term planning of future water resources and reservoir management, as well as for future design criteria. The expected warmer winters with possible alternance of snow accumulation and melt, for example, represent a new challenge for reservoir planning. Finally, uncertainties in the projected changes are considered and discussed, as well as the impact of methodological choices along the modeling process.

  5. List of participants at SIDE IV meeting, Tokyo, 27 November--1 December 2000

    NASA Astrophysics Data System (ADS)

    2001-12-01

    Mark J Ablowitz, Vsevolod Adler, Mark Alber, Said Belmehdi, Marco Boiti, Claude Brezinski, R Bullough, Y M Chiang, Theodore Chihara, Peter A Clarkson, Robert Conte, Adam Doliwa, Vladimir Dorodnitsyn, Mitsuaki Eguchi, Claire Gilson, Basil Grammaticos, Valeri Gromak, Rod Halburd, Koji Hasegawa, Jarmo Hietarinta, Ryogo Hirota, Xing Biao Hu, M Idzumi, J Inoguchi, Hiroya Ishikara, Mourad Ismail, Shin Isojima, Kenichi Ito, Yoshiaki Itoh, Masashi Iwasaki, Klara Janglajew, Michio Jimbo, Nalini Joshi, Kenji Kajiwara, Saburo Kakei, Masaru Kamata, Satoshi Kamei, Rinat Kashaev, Shingo Kawai, Taeko Kimijima, K Kimura, Anatol Kirillov, Koichi Kondo, Boris Konopelchenko, Martin Kruskal, Atsuo Kuniba, Wataru Kunishima, Franklin Lambert, Serguei Leble, Decio Levi, Shigeru Maeda, Manuel Manas, Ken-Ichi Maruno, Tetsu Masuda, J Matsukidaira, Atsushi Matsumiya, Shigeki Matsutani, Yukitaka Minesaki, Mikio Murata, Micheline Musette, Atsushi Nagai, Katsuya Nakagawa, Atsushi Nakamula, Akira Nakamura, Yoshimasa Nakamura, Frank Nijhoff, J J C Nimmo, Katsuhiro Nishinari, Michitomo Nishizawa, A Nobe, Masatoshi Noumi, Yaeko Ohsaki, Yasuhiro Ohta, Kazuo Okamoto, Alexandre Orlov, Naoki Osada, Flora Pempinelli, Spiro Pyrlis, Reinout Quispel, Orlando Ragnisco, Alfred Ramani, Jean-Pierre Ramis, Andreas Ruffing, Simon Ruijsenaars, Satoru Saito, Noriko Saitoh, Hidetaka Sakai, Paulo Santini, Narimasa Sasa, Ryu Sasaki, Yoshikatsu Sasaki, Junkichi Satsuma, Sergei Sergeev, Nobuhiko Shinzawa, Evgueni Sklyanin, Juris Suris, Norio Suzuki, Yukiko Tagami, Katsuaki Takahashi, Daisuke Takahashi, Tomoyuki Takenawa, Yoshiro Takeyama, K M Tamizhmani, T Tamizhmani, Kouichi Toda, Morikatsu Toda, Tetsuji Tokihiro, Takayuki Tsuchida, Yohei Tsuchiya, Teruhisa Tsuda, Satoru Tsujimoto, Walter Van Assche, Claude Viallet, Luc Vinet, Shinsuke Watanabe, Yoshihida Watanabe, Ralph Willox, Pavel Winternitz, Yasuhiko Yamada, Yuji Yamada, Jin Yoneda, Haruo Yoshida, Katsuhiko Yoshida, Daisuke Yoshihara, Fumitaka Yura, J Zagrodzinski, Alexei Zhedanov

  6. Effect of Lactobacillus brevis KB290 on the cell-mediated cytotoxic activity of mouse splenocytes: a DNA microarray analysis.

    PubMed

    Fukui, Yuichiro; Sasaki, Erika; Fuke, Nobuo; Nakai, Yuji; Ishijima, Tomoko; Abe, Keiko; Yajima, Nobuhiro

    2013-11-14

    Lactic acid bacteria confer a variety of health benefits. Here, we investigate the mechanisms by which Lactobacillus brevis KB290 (KB290) enhances cell-mediated cytotoxic activity. Female BALB/c mice aged 9 weeks were fed a diet containing KB290 (3 × 10(9) colony-forming units/g) or starch for 1 d. The resulting cytotoxic activity of splenocytes against YAC-1 cells was measured using flow cytometry and analysed for gene expression using DNA microarray technology. KB290 enhanced the cell-mediated cytotoxic activity of splenocytes. DNA microarray analysis identified 327 up-regulated and 347 down-regulated genes that characterised the KB290 diet group. The up-regulated genes were significantly enriched in Gene Ontology terms related to immunity, and, especially, a positive regulation of T-cell-mediated cytotoxicity existed among these terms. Almost all the genes included in the term encoded major histocompatibility complex (MHC) class I molecules involved in the presentation of antigen to CD8(+) cytotoxic T cells. Marco and Signr1 specific to marginal zone macrophages (MZM), antigen-presenting cells, were also up-regulated. Flow cytometric analysis confirmed that the proportion of MZM was significantly increased by KB290 ingestion. Additionally, the over-represented Kyoto Encyclopedia of Genes and Genomes pathways among the up-regulated genes were those for natural killer (NK) cell-mediated cytotoxicity and antigen processing and presentation. The results for the selected genes associated with NK cells and CD8(+) cytotoxic T cells were confirmed by quantitative RT-PCR. These results suggest that enhanced cytotoxic activity could be caused by the activation of NK cells and/or of CD8(+) cytotoxic T cells stimulated via MHC class I presentation. PMID:23544404

  7. Effects of chronic electrical stimulation on paralyzed expiratory muscles

    PubMed Central

    DiMarco, Anthony F.; Kowalski, Krzysztof E.

    2013-01-01

    Following spinal cord injury, the expiratory muscles develop significant disuse atrophy characterized by reductions in their weight, fiber cross-sectional area, and force-generating capacity. We determined the extent to which these physiological alterations can be prevented with electrical stimulation. Because a critical function of the expiratory muscles is cough generation, an important goal was the maintenance of maximal force production. In a cat model of spinal cord injury, short periods of high-frequency lower thoracic electrical spinal cord stimulation (SCS) at the T10 level (50 Hz, 15 min, twice/day, 5 days/wk) were initiated 2 wk following spinalization and continued for a 6-mo period. Airway pressure (P)-generating capacity was determined by SCS. Five acute, spinalized animals served as controls. Compared with controls, initial P fell from 43.9 1.0 to 41.8 0.7 cmH2O (not significant) in the chronic animals. There were small reductions in the weight of the external oblique, internal oblique, transverses abdominis, internal intercostal, and rectus abdominis muscles (not significant for each). There were no significant changes in the population of fast muscle fibers. Because prior studies (Kowalski KE, Romaniuk JR, DiMarco AF. J Appl Physiol 102: 1422-1428, 2007) have demonstrated significant atrophy following spinalization in this model, these results indicate that expiratory muscle atrophy can be prevented by the application of short periods of daily high-frequency stimulation. Because the frequency of stimulation is similar to the expected pattern of clinical use for cough generation, the daily application of electrical stimulation could potentially serve the dual purpose of maintenance of expiratory muscle function and airway clearance. PMID:18403449

  8. Misperceiving Bullshit as Profound Is Associated with Favorable Views of Cruz, Rubio, Trump and Conservatism.

    PubMed

    Pfattheicher, Stefan; Schindler, Simon

    2016-01-01

    The present research investigates the associations between holding favorable views of potential Democratic or Republican candidates for the US presidency 2016 and seeing profoundness in bullshit statements. In this contribution, bullshit is used as a technical term which is defined as communicative expression that lacks content, logic, or truth from the perspective of natural science. We used the Bullshit Receptivity scale (BSR) to measure seeing profoundness in bullshit statements. The BSR scale contains statements that have a correct syntactic structure and seem to be sound and meaningful on first reading but are actually vacuous. Participants (N = 196; obtained via Amazon Mechanical Turk) rated the profoundness of bullshit statements (using the BSR) and provided favorability ratings of three Democratic (Hillary Clinton, Martin O'Malley, and Bernie Sanders) and three Republican candidates for US president (Ted Cruz, Marco Rubio, and Donald Trump). Participants also completed a measure of political liberalism/conservatism. Results revealed that favorable views of all three Republican candidates were positively related to judging bullshit statements as profound. The smallest correlation was found for Donald Trump. Although we observe a positive association between bullshit and support for the three Democrat candidates, this relationship is both substantively small and statistically insignificant. The general measure of political liberalism/conservatism was also related to judging bullshit statements as profound in that individuals who were more politically conservative had a higher tendency to see profoundness in bullshit statements. Of note, these results were not due to a general tendency among conservatives to see profoundness in everything: Favorable views of Republican candidates and conservatism were not significantly related to profoundness ratings of mundane statements. In contrast, this was the case for Hillary Clinton and Martin O'Malley. Overall, small-to-medium sized correlations were found, indicating that far from all conservatives see profoundness in bullshit statements. PMID:27128318

  9. SuperB: a Linear High-Luminosity B Factory

    SciTech Connect

    Albert, J.; Bettarini, S.; Biagini, M.; Bonneaud, G.; Cai, Y.; Calderini, G.; Ciuchini, M.; Dubois-Felsmann, G.P.; Ecklund, S.; Forti, F.; Gershon, T.J.; Giorgi, M.A.; Hitlin, D.G.; Leith, D.W.G.S.; Lusiani, A.; MacFarlane, D.B.; Martinez-Vidal, F.; Neri, N.; Novokhatski, A.; Pierini, M.; Piredda, G.; /Caltech /Pisa U. /Pisa, Scuola Normale Superiore /INFN, Pisa /Frascati /Ecole Polytechnique /SLAC /Rome III U. /INFN, Rome3 /Warwick U. /Valencia U., IFIC /Wisconsin U., Madison /Rome U. /INFN, Rome /Edinburgh U. /Orsay, LAL

    2006-02-08

    This paper is based on the outcome of the activity that has taken place during the recent workshop on ''SuperB in Italy'' held in Frascati on November 11-12, 2005. The workshop was opened by a theoretical introduction of Marco Ciuchini and was structured in two working groups. One focused on the machine and the other on the detector and experimental issues.. The present status on CP is mainly based on the results achieved by BABAR and Belle. Establishment of the indirect CP violation in B sector in 2001 and of the direct CP violation in 2004 thanks to the success of PEP-II and KEKB e{sup +}e{sup -} asymmetric B Factories operating at the center of mass energy corresponding to the mass of the {Upsilon}(4S ). With the two B Factories taking data, the Unitarity Triangle is now beginning to be over constrained by improving the measurements of the sides and now also of the angles {alpha}, and {gamma}. We are also in presence of the very intriguing results about the measurements of sin2{beta} in the time dependent analysis of decay channels via penguin loops, where b {yields} s{bar s}s and b {yields} s{bar d}d. {tau} physics, in particular LFV search, as well as charm and ISR physics are important parts of the scientific program of a SuperB Factory. The physics case together with possible scenarios for the high luminosity SuperB Factory based on the concepts of the Linear Collider and the related experimental issues are discussed.

  10. TIR Emissivity Spectra of Thermally Processed Sulfates, Carbonates and Phyllosilicates as Analog Materials for Asteroid Surfaces

    NASA Astrophysics Data System (ADS)

    Maturilli, A.; Helbert, J.; D'Amore, M.; Ferrari, S.

    2013-12-01

    At the Planetary Emissivity Laboratory (PEL) of the German Aerospace Center (DLR) in Berlin we are building a database of spectral measurements of several meteorites and other analogs for asteroid surfaces. Bi-directional reflectance of samples in the 1 to 100 ?m spectral range, are measured by using an evacuated (10-4 bar) Bruker Vertex 80V FTIR spectrometer and a Bruker A513 reflection unit, allowing phase angles between 26 and 170. Emissivity in the 1 to 100 ?m spectral range is measured with the same instrument coupled with an external emissivity chamber, for sample temperatures ranging from low (50 C) to very high (above 800 C). We present here new measurements on sulfates, carbonates, and phyllosilicates in various grain size ranges. The setup was configured to simulate the thermal history of surface minerals on the asteroid 2008 EV5 during its revolution around the Sun. This asteroid is the scientific target of the ESA Marco Polo-R mission. The samples in vacuum (< 0.8 mbar) are measured at surface temperature around 70 C, then the same samples are heated to 220 C, and maintained at this temperature for one hour. Slowly the sample temperature is reduced back again to 70 C and a second measurement is taken. Emissivity spectra before and after thermal processing of the samples are complemented with reflectance measurements on samples fresh and after thermal processing. This comparison show us that for some minerals no spectral/structural changes appear, while others show signs of dehydration and among them some species show structural changes. We conclude that a proper spectral library of emissivity spectra for asteroid analogue materials must include thermally processed samples, reproducing the thermal evolution for the asteroid that is target of the actual investigation.

  11. Hipparcos Venice 97 Symposium

    NASA Astrophysics Data System (ADS)

    1997-04-01

    Carried into orbit by an Ariane 4 launcher in 1989, ESA's astrometric satellite Hipparcos monitored 118,218 stars during a period of four years taking the first accurate census of the stars that populate our galaxy. The measurements, precise to one millionth of a degree - a hundred time more precise than equivalent measurements taken by the most sophisticated ground-based observatories- are collected in a catalogue (the Hipparcos Catalogue) to be available to the international community of scientist in June this year. A second catalogue (the Tycho Catalogue) gives positions and proper motions of 1,038,332 stars with a precision of one hundred thousandth of a degree. The Hipparcos Symposium in Venice will mark the completion of the Hipparcos and Tycho Catalogues and will also be the first occasion at which the scientific results arising from the mission will be presented and discussed. Co-sponsored by Matra Marconi Space and Alenia Spazio, the industrial architects of the Hipparcos spacecraft, this symposium will be held at Fondazione Cini, on the Island of S. Giorgio, under the auspices of the City of Venice. A daily summary of the Symposium works will be available as of 13 May on Internet at the following URL: http://www.estec.esa.nl/spdwww/hipparcos/V97/ or under the What's New section of ESA's Science pages on the web at http://www.estec.esa.nl/spdwww/h2000/html/whatsnew.htm An open air exhibition on Riva Ca' di Dio, a Venetian quay near the Piazza San Marco, open 1-25 May 1997, echoes the Symposium and catches the attention of the public at large with full size models of the Hipparcos, ISO and SOHO scientific satellites: advanced space science amidst Venetian palaces, history and art.

  12. A Land-Use Perspective for Birdstrike Risk Assessment: The Attraction Risk Index

    PubMed Central

    Coccon, Francesca; Zucchetta, Matteo; Bossi, Giulia; Borrotti, Matteo; Torricelli, Patrizia; Franzoi, Piero

    2015-01-01

    Collisions between aircraft and birds, birdstrikes, pose a serious threat to aviation safety. The occurrence of these events is influenced by land-uses in the surroundings of airports. Airports located in the same region might have different trends for birdstrike risk, due to differences in the surrounding habitats. Here we developed a quantitative tool that assesses the risk of birdstrike based on the habitats within a 13-km buffer from the airport. For this purpose, we developed Generalized Linear Models (GLMs) with binomial distribution to estimate the contribution of habitats to wildlife use of the study area, depending on season. These GLMs predictions were combined to the flight altitude of birds within the 13-km buffer, the airport traffic pattern and the severity indices associated with impacts. Our approach was developed at Venice Marco Polo International airport (VCE), located in northeast Italy and then tested at Treviso Antonio Canova International airport (TSF), which is 20 km inland. Results from the two airports revealed that both the surrounding habitats and the season had a significant influence to the pattern of risk. With regard to VCE, agricultural fields, wetlands and urban areas contributed most to the presence of birds in the study area. Furthermore, the key role of distance of land-uses from the airport on the probability of presence of birds was highlighted. The reliability of developed risk index was demonstrated since at VCE it was significantly correlated with bird strike rate. This study emphasizes the importance of the territory near airports and the wildlife use of its habitats, as factors in need of consideration for birdstrike risk assessment procedures. Information on the contribution of habitats in attracting birds, depending on season, can be used by airport managers and local authorities to plan specific interventions in the study area in order to lower the risk. PMID:26114958

  13. Coupled expression of troponin T and troponin I isoforms in single skeletal muscle fibers correlates with contractility

    PubMed Central

    BROTTO, MARCO A.; BIESIADECKI, BRANDON J.; BROTTO, LETICIA S.; NOSEK, THOMAS M; JIN, J.-P.

    2005-01-01

    (Summary) Brotto, Marco A., Brandon J. Biesiadecki, Leticia S. Brotto, Thomas M. Nosek, and J.-P. Jin. Striated muscle contraction is powered by actin-activated myosin ATPase. This process is regulated by Ca2+ via the troponin complex. Slow and fast twitch fibers of vertebrate skeletal muscle express type I and type II myosin, respectively, and these myosin isoenzymes confer different ATPase activities, contractile velocities and force. Skeletal muscle troponin has also diverged into fast and slow isoforms, but their functional significance is not fully understood. To investigate the expression of troponin isoforms in mammalian skeletal muscle and their functional relationship to that of the myosin isoforms, we concomitantly studied myosin and troponin T (TnT) and troponin I (TnI) isoform contents and isometric contractile properties in single fibers of rat skeletal muscle. We characterized a large number of Triton skinned single fibers from soleus, diaphragm, gastrocnemius and extensor digitorum longus muscles and selected fibers with combinations of a single myosin isoform and a single class (slow or fast) of TnT and TnI isoform to investigate their role in determining contractility. Type IIa, IIx and IIb myosin fibers produced higher isometric force than that of type I fibers. Despite the polyploidy of adult skeletal muscle fibers, the expression of fast or slow isoforms of TnT and TnI is tightly coupled. Fibers containing slow troponin had higher Ca2+ sensitivity than that of the fast troponin fibers, while fibers containing fast troponin showed a higher cooperativity of Ca2+ activation than that of the slow troponin fibers. The results demonstrate distinctive, but coordinated, regulation of troponin and myosin isoform expression in skeletal muscle and their contribution to the contractile properties. PMID:16192301

  14. Sedimentary evolution of the Mesozoic continental redbeds using geochemical and mineralogical tools: the case of Upper Triassic to Lowermost Jurassic Monte di Gioiosa mudrocks (Sicily, southern Italy)

    NASA Astrophysics Data System (ADS)

    Perri, Francesco; Critelli, Salvatore; Mongelli, Giovanni; Cullers, Robert L.

    2011-10-01

    The continental redbeds from the Internal Domains of the central-western Mediterranean Chains have an important role in the palaeogeographic and palaeotectonic reconstructions of the Alpine circum-Mediterranean orogen evolution since these redbeds mark the Triassic-Jurassic rift-valley stage of Tethyan rifting. The composition and the sedimentary evolution of the Middle Triassic to Lowermost Jurassic continental redbeds of the San Marco d'Alunzio Unit (Peloritani Mountains, Southern Italy), based on mineralogical and chemical analyses, suggests that the studied mudrock sediments share common features with continental redbeds that constitute the Internal Domains of the Alpine Mediterranean Chains. Phyllosilicates are the main components in the mudrocks. The 10 Å-minerals (illite and micas), the I-S mixed layers, and kaolinite are the most abundant phyllosilicates. The amount of illitic layers in I-S mixed layers coupled with the illite crystallinity values (IC) are typical of high degree of diagenesis, corresponding to a lithostatic/tectonic loading of about 4-5 km. The mineralogical assemblage coupled with the A-CN-K plot suggest post-depositional K-enrichments. Palaeoweathering proxies (PIA and CIW) record intense weathering at the source area. Further, the studied sediments are affected by reworking and recycling processes and, as consequence, it is likely these proxies monitor cumulative effect of weathering. The climate in the early Jurassic favoured recycling and weathering occurred under hot, episodically humid climate with a prolonged dry season. The source-area is the low-grade Paleozoic metasedimentary basement. Mafic supply is minor but not negligible as suggested by provenance proxies.

  15. Effect of warming on the altitudinal distribution of soil moisture and net primary production in a synthetic mountain catchment

    NASA Astrophysics Data System (ADS)

    Maneta, M. P.

    2011-12-01

    Marco P Maneta Dept of Geosciences, University of Montana, Missoula, MT 59812 Generally, the trend towards a warmer climate is thought to lead to a more water-stressed environment. This signal has been sought and detected in the analysis of snow water equivalent and river discharge data from the network of SNOTEL sites and river gauges, in the frequency of forest fires and in the shift of species uphill in elevation. While at a large scale this trend is well documented, local departures are expected, especially in regions of complex topography. Recent studies show that in mountain regions, small scale atmospheric processes can significantly alter the local climate leading to counterintuitive results such as increased precipitation and increased snowpack that results in increased moisture regimes and larger spring peak stream flows. A recent study has observed a significant downhill shift in the optimal elevation of plant species in the last century in California, this shift being attributed to increased energy and moisture availability and demonstrating that temperature and energy alone, as used in many ecological models, do not adequately explain the distribution of vegetation. Using an ecohydrologic model on a synthetic mountain setting we investigate how changes in the temperature regime (defined by the average temperature and lapse rate) and altitudinal distribution of precipitation lead to changes in the altitudinal distribution of soil moisture and primary production, including a downhill shift in primary production. This is because earlier snowmelt increases the amount of available water despite the expected increase of atmospheric water demand associated with higher temperatures.

  16. Transitioning the respiratory therapy workforce for 2015 and beyond.

    PubMed

    Barnes, Thomas A; Kacmarek, Robert M; Kageler, Woody V; Morris, Michael J; Durbin, Charles G

    2011-05-01

    The American Association for Respiratory Care established a task force in late 2007 to identify likely new roles and responsibilities of respiratory therapists (RTs) in the year 2015 and beyond. A series of 3 conferences was held between 2008 and 2010. The first task force conference affirmed that the healthcare system is in the process of dramatic change, driven by the need to improve health while decreasing costs and improving quality. This will be facilitated by application of evidence-based care, prevention and management of disease, and closely integrated interdisciplinary care teams. The second task force conference identified specific competencies needed to assure safe and effective execution of RT roles and responsibilities in the future. The third task force conference was charged with creating plans to change the professional education process so that RTs are able to achieve the needed skills, attitudes, and competencies identified in the previous conferences. Transition plans were developed by participants after review and discussion of the outcomes of the first two conferences and 1,011 survey responses from RT department managers and RT education program directors. This is a report of the recommendations of the third task force conference held July 12-14, 2010, on Marco Island, Florida. The participants, who represented groups concerned with RT education, licensure, and practice, proposed, discussed, and accepted that to be successful in the future a baccalaureate degree must be the minimum entry level for respiratory care practice. Also accepted was the recommendation that the Certified Respiratory Therapist examination be retired, and instead, passing of the Registered Respiratory Therapist examination will be required for beginning clinical practice. A date of 2020 for achieving these changes was proposed, debated, and accepted. Recommendations were approved requesting resources be provided to help RT education programs, existing RT workforce, and state societies work through the issues raised by these changes. PMID:21276324

  17. Singing sand as an instability arising from a shear-plug flow

    NASA Astrophysics Data System (ADS)

    Dagois-Bohy, Simon; Courrech Du Pont, Sylvain; Douady, Stéphane

    2010-05-01

    Desert sand dunes can have the peculiar ability to emit a loud sound up to 110 dB, with a well-defined frequency: this is the song of the dunes. After the early travelers who first mentioned it (Darwin, Marco-Polo, ...) later scientific observations have shown that if not all dunes sing, all the singing dunes are composed of dry, well-sorted and coated sand; this sound occurs when the sand is sheared, and particularly on field during avalanches on a slip face of a singing dune? Several observations—recent and less recent—have shown that the sound frequency is likely equal to the shear rate of the flow, or at least is varying in the same way. We have been able to reproduce these avalanches in laboratory on an inclined plane with singing sand from Morocco and Oman, which has made possible to study them more accurately than on the field. Signals of accelerometers measuring local vertical oscillations of the flowing surface show that the phenomenon does not require resonance in the depth or in the dune. Measures of velocity and flow rate during avalanches enhance the co-existence of a plug flow with a large shear band underneath, both strongly correlated to the sound emission. A new model has been developed, based on the mechanical interaction between the plug area and the transient force chains in the flow. This model predicts a threshold that depends on the compacity of the granular media and on the surface friction and adhesion properties of the grains, and the value predicted fits quantitively well the data collected from avalanches, as well as from other experimental set-up of singing sand.

  18. Misperceiving Bullshit as Profound Is Associated with Favorable Views of Cruz, Rubio, Trump and Conservatism

    PubMed Central

    Pfattheicher, Stefan; Schindler, Simon

    2016-01-01

    The present research investigates the associations between holding favorable views of potential Democratic or Republican candidates for the US presidency 2016 and seeing profoundness in bullshit statements. In this contribution, bullshit is used as a technical term which is defined as communicative expression that lacks content, logic, or truth from the perspective of natural science. We used the Bullshit Receptivity scale (BSR) to measure seeing profoundness in bullshit statements. The BSR scale contains statements that have a correct syntactic structure and seem to be sound and meaningful on first reading but are actually vacuous. Participants (N = 196; obtained via Amazon Mechanical Turk) rated the profoundness of bullshit statements (using the BSR) and provided favorability ratings of three Democratic (Hillary Clinton, Martin O’Malley, and Bernie Sanders) and three Republican candidates for US president (Ted Cruz, Marco Rubio, and Donald Trump). Participants also completed a measure of political liberalism/conservatism. Results revealed that favorable views of all three Republican candidates were positively related to judging bullshit statements as profound. The smallest correlation was found for Donald Trump. Although we observe a positive association between bullshit and support for the three Democrat candidates, this relationship is both substantively small and statistically insignificant. The general measure of political liberalism/conservatism was also related to judging bullshit statements as profound in that individuals who were more politically conservative had a higher tendency to see profoundness in bullshit statements. Of note, these results were not due to a general tendency among conservatives to see profoundness in everything: Favorable views of Republican candidates and conservatism were not significantly related to profoundness ratings of mundane statements. In contrast, this was the case for Hillary Clinton and Martin O’Malley. Overall, small-to-medium sized correlations were found, indicating that far from all conservatives see profoundness in bullshit statements. PMID:27128318

  19. "We will not rest." Filipino women want a fertility management program that respects women's dignity, women's bodies and women's choices.

    PubMed

    Alvarez, R O

    1993-03-01

    The program officer for the Institute for Social Studies and Action presents 1) her views on women's fertility management under different political administrations in the Philippines, 2) the political postures of influential groups, 3) the goals of women's and health groups, and 4) the actions taken by Filipino women. Under Ferdinand Marcos, the official family planning (FP) program emphasized reduction of population growth and established a quota system and incentives for the number of new acceptors. Women, as a result, became victims; e.g. IUDs were inserted without prior knowledge, and inadequate information and follow-up were provided on oral contraceptive use. Efforts were criticized for treating women as program targets and not as individuals capable of making choices. Under Corazon Aquino, the Roman Catholic hierarchy dominated and would have banned all forms of artificial contraception had women's and health groups not blocked the effort. Only in 1989 did President Aquino finally announce that multiple methods of family planning (FP) would be promoted. There was a transition in program services during the transfer to the Department of Health. Currently the government promotes FP within the safe motherhood and child survival context, but adolescents and unmarried women and couples are excluded from FP services. Population control advocates believe FP is a health issue. The Roman Catholic Church accepts only natural methods and believes artificial methods interfere with the natural processes of procreation. Anti-FP groups promote only natural FP methods and wage campaigns to discredit contraceptive methods. Women's and FP groups contend that it is a woman's right to regulate her own fertility. Safe abortion should be made available to those who need it. Women's networks are mobilizing to talk about the issues, to hold public activities to change laws and policies and to encourage women's involvement in decision making affecting their lives, and to conduct research specific to women's views. Women's organizations will be active until safe, affordable, accessible, and appropriate fertility management is available to all women. PMID:12286371

  20. The Solar Probe Mission Study: 2004

    NASA Astrophysics Data System (ADS)

    Hassler, D. M.; Solar Probe Science and Technology Definition STDT* Team

    2004-05-01

    Solar Probe will experience first hand the processes and conditions in the solar atmosphere that ultimately impact our planet and shape the harsh solar system environment. It will be humanity's first visit to a star and will explore a previously inaccessible region of the inner heliosphere. The 2003 Space Science Enterprise Strategy called for study of a Solar Probe to "fly through the solar atmosphere to answer fundamental questions that can be answered in no other way." The mission received highest priority in the National Academy of Sciences' decadal research strategy in solar and space physics in 2002. Significant advances have been made in the areas of solar and solar wind science, instrument technology, mission resources, and the mission environment since the previous Solar Probe Science Definition Team reports of 1989, 1995, and 1999. Therefore, with the strong support from the international community, NASA's Office of Space Science (OSS) has formed a new Science and Technology Definition Team (STDT) to develop an exciting and achievable new mission concept for a Solar Probe mission. It is hoped that this study will be completed this fall with a final report by the end of 2004. This talk provides an update on the progress of the STDT's efforts. *Solar Probe Science and Technology Definition Team (STDT): Loren Acton, Marianne Balat, Volker Bothmer, Ray Dirling, Bill Feldman, George Gloeckler, Shadia Habbal, Don Hassler, Geoffrey Landis, Ingrid Mann, Bill Matthaeus, Dave McComas, Ralph McNutt, Dick Mewaldt, Neil Murphy, Leon Ofman, Ed Sittler, Chuck Smith, Marco Velli, and Thomas Zurbuchen

  1. Analysis of the effects of meteorology on aircraft exhaust dispersion and deposition using a Lagrangian particle model.

    PubMed

    Pecorari, Eliana; Mantovani, Alice; Franceschini, Chiara; Bassano, Davide; Palmeri, Luca; Rampazzo, Giancarlo

    2016-01-15

    The risk of air quality degradation is of considerable concern particularly for those airports that are located near urban areas. The ability to quantitatively predict the effects of air pollutants originated by airport operations is important for assessing air quality and the related impacts on human health. Current emission regulations have focused on local air quality in the proximity of airports. However, an integrated study should consider the effects of meteorological events, at both regional and local level, that can affect the dispersion and the deposition of exhausts. Rigorous scientific studies and extensive experimental data could contribute to the analysis of the impacts of airports expansion plans. This paper is focused on the analysis of the effects of meteorology on aircraft emission for the Marco Polo Airport in Venice. This is the most important international airport in the eastern part of the Po' Valley, one of the most polluted area in Europe. Air pollution is exacerbated by meteorology that is a combination of large and local scale effects that do not allow significant dispersion. Moreover, the airport is located near Venice, a city of noteworthy cultural and architectural relevance, and nearby the lagoon that hosts several areas of outstanding ecological importance at European level (Natura 2000 sites). Dispersion and deposit of the main aircraft exhausts (NOx, HC and CO) have been evaluated by using a Lagrangian particle model. Spatial and temporal aircraft exhaust dispersion has been analyzed for LTO cycle. Aircraft taxiing resulted to be the most impacting aircraft operation especially for the airport working area and its surroundings, however occasionally peaks may be observed even at high altitudes when cruise mode starts. Mixing height can affect concentrations more significantly than the concentrations in the exhausts themselves. An increase of HC and CO concentrations (15-50%) has been observed during specific meteorological events. PMID:26437354

  2. Functional Genomics of Innate Host Defense Molecules in Normal Human Monocytes in Response to Aspergillus fumigatus †

    PubMed Central

    Cortez, Karoll J.; Lyman, Caron A.; Kottilil, Shyam; Kim, Hee Sup; Roilides, Emmanuel; Yang, Jun; Fullmer, Brandie; Lempicki, Richard; Walsh, Thomas J.

    2006-01-01

    Aspergillus fumigatus induces the release of innate immune-related molecules from phagocytic cells early in the course of infection. Little is known, however, about the complex expression profiles of the multiple genes involved in this response. We therefore investigated the kinetics of early gene expression in human monocytes (HMCs) infected with conidia of A. fumigatus using DNA microarray analysis. Total RNA from HMCs at 0, 2, 4, and 6 h was extracted, linearly amplified, hybridized onto Affymetrix HG133 Plus 2.0 gene chips, and analyzed with an Affymetrix scanner. Changes in gene expression were calculated as a ratio of those expressed by infected versus control HMCs. Aspergillus fumigatus induced differential regulation of expression in 1,827 genes (P < 0.05). Genes encoding cytokines and chemokines involved in host defense against A. fumigatus, including interleukin-1β (IL-1β), IL-8, CXCL2, CCL4, CCL3, and CCL20, as well as the opsonin long pentraxin 3, were up-regulated during the first 2 to 6 h, coinciding with an increase in phagocytosis. Simultaneously, genes encoding CD14, ficolin1, and MARCO were down-regulated, and genes encoding IL-10 and matrix metalloproteinase 1 were up-regulated. Up-regulation of the genes encoding heat shock proteins 40 and 110 and connexins 26 and 30 may point to novel molecules whose role in the pathogenesis of aspergillosis has not been previously reported. Verification of the transcriptional profiling was obtained for selected genes by reverse transcription-PCR and enzyme immunoassay. Thus, A. fumigatus conidia induced a coordinated expression of genes important in host defense and immunomodulation. PMID:16552065

  3. Hyperspectral remote sensing techniques applied to the noninvasive investigation of mural paintings: a feasibility study carried out on a wall painting by Beato Angelico in Florence

    NASA Astrophysics Data System (ADS)

    Cucci, Costanza; Picollo, Marcello; Chiarantini, Leandro; Sereni, Barbara

    2015-06-01

    Nowadays hyperspectral imaging is a well-established methodology for the non-invasive diagnostics of polychrome surfaces, and is increasingly utilized in museums and conservation laboratories for documentation purposes and in support of restoration procedures. However, so far the applications of hyperspectral imaging have been mainly limited to easel paintings or paper-based artifacts. Indeed, specifically designed hyperspectral imagers, are usually used for applications in museum context. These devices work at short-distances from the targets and cover limited size surfaces. Instead, almost still unexplored remain the applications of hyperspectral imaging to the investigations of frescoes and large size mural paintings. For this type of artworks a remote sensing approach, based on sensors capable of acquiring hyperspectral data from distances of the order of tens of meters, is needed. This paper illustrates an application of hyperspectral remote sensing to an important wall-painting by Beato Angelico, located in the San Marco Museum in Florence. Measurements were carried out using a re-adapted version of the Galileo Avionica Multisensor Hyperspectral System (SIM-GA), an avionic hyperspectral imager originally designed for applications from mobile platforms. This system operates in the 400-2500 nm range with over 700 channels, thus guaranteeing acquisition of high resolution hyperspectral data exploitable for materials identification and mapping. In the present application, the SIM-GA device was mounted on a static scanning platform for ground-based applications. The preliminary results obtained on the Angelico's wall-painting are discussed, with highlights on the main technical issues addressed to optimize the SIM-GA system for new applications on cultural assets.

  4. Impact of socio-demographic, socioeconomic, and water variables on dental fluorosis in adolescents growing up during the implementation of a fluoridated domestic salt program.

    PubMed

    Pontigo-Loyola, América P; Medina-Solís, Carlo E; Lara-Carrillo, Edith; Patiño-Marín, Nuria; Escoffié-Ramirez, Mauricio; Mendoza-Rodríguez, Martha; De La Rosa-Santillana, Rubén; Maupomé, Gerardo

    2014-01-01

    The objective of this study is to determine the impact of socio-demographic, socioeconomic, and other risk indicators on dental fluorosis (DF) among Mexican adolescents. A cross-sectional study was carried out in 1,538 adolescents 12 and 15 years of age in semi-rural communities located at high altitude (>2,000 m) and with high concentration of fluoride in water (1.38-3.07 ppm) in Hidalgo, Mexico. DF was determined by means of Dean's Index and all teeth were examined. Remaining variables were collected using a questionnaire. The adjusted final model was performed using ordered logistic regression. After adjusting for sex, the variables associated with DF were (p < 0.05): being 12 years old (OR = 1.10) versus 15 years old; having lived the first 6 years of life in El Llano (3.07 F ppm) (OR = 3.19) or San Marcos (1.38 F ppm) (OR = 1.63) versus Tula (1.42 F ppm); having public (OR = 1.35) or private health insurance (OR = 1.36) versus those without insurance; belonging to the lower quartiles of socioeconomic position (SEP) [1st quartile (OR = 2.48), 2nd quartile (OR = 1.81), 3rd quartile (OR = 1.49)] versus the highest quartile; having drunk tap water (OR = 1.83) or from a well or spring (OR = 2.30) versus those who drank water purchased in large containers or bottles. Demographic and socioeconomic variables were associated with DF. While better SEP appeared to play an important role in DF, a pattern of water intake associated with water purchased in large containers or bottles (which have different connotations to the use of bottled water in industrialized Western countries) did reduce DF risk in these high fluoride content, high altitude communities. PMID:23224521

  5. The Fascinating Quest of Asteroids: The Remnants of Planetary Formation

    NASA Astrophysics Data System (ADS)

    Michel, Patrick

    2012-10-01

    Asteroids are the leftover building blocks of the terrestrial planets and offer clues to the chemical mixture from which the planets formed. Current studies suggest that asteroid impacts in the early history of our planet may have delivered the necessary material for the emergence of life. In our current epoch, collisions of asteroids with the Earth pose a finite hazard and the design of efficient mitigation strategies relies on our knowledge of their physical properties. For all these reasons, the exploration of asteroids is a fascinating quest. This presentation will provide a basic overview of our current knowledge of asteroids, thanks in particular to space missions, observations and numerical models that allow exploring the different processes that they undergo during their evolutions. What are asteroids? Are they our friends or enemies? Amazing real images and movies of asteroids, which are stunning in their diversity, will be shown and discussed, as well as movies of numerical simulations of collisions and surface evolutions. Among other things, the first detailed images of a Near-Earth Asteroid, Eros, obtained by NASA’s NEAR mission in 2000-2001, will be presented, as well as images of Vesta, the second largest asteroid, from NASA’s Dawn mission. The fantastic adventure of the Japanese mission Hayabusa , which successfully returned to Earth a sample from the smallest asteroid ever visited in 2010, will also be discussed. Missions under development at NASA (OSIRIS-Rex), JAXA (Hayabusa 2), and under study at ESA (MarcoPolo-R), each with the goal of returning a sample from a possibly organic-rich asteroid, will also be presented. This fascinating quest continues and it is already clear that the next visits to asteroids will keep turning our understanding on its head and provide a wealth of exciting data to future generations of researchers.

  6. Electronic and thermoelectric properties of Mexican hat bands in van-der-Waals materials

    NASA Astrophysics Data System (ADS)

    Wickramaratne, Darshana; Zahid, Ferdows; Lake, Roger

    2015-03-01

    Mexican hat dispersions are relatively common in few-layer two-dimensional materials. In one to four monolayers of the group-III chalcogenides (GaS, GaSe, InS, InSe) and Bi2Se3 the valence band undergoes a band inversion from a parabolic to an inverted Mexican hat dispersion as the film thickness is reduced from bulk to a single monolayer. The band inversion is robust against changes in stacking order, omission or inclusion of spin-orbit coupling and the choice of functional. The Mexican hat dispersion results in a 1/√{ E} singularity in the two-dimensional density of states and a step-function turn on in the density of modes. The largest radius of the ring of states occurs for a single monolayer of each material. The dispersion with the largest radius coincides with the maximum power factor and ZT for a material at room temperature. Ab-initio electronic structure calculations are used with a Landauer approach to calculate the thermoelectric transport coefficients. Analytical models of the Mexican hat and the parabolic dispersions are used for comparison and analysis. Vertically biased bilayer graphene could serve as an experimental test-bed for measuring this effect since the radius of the Mexican hat band edge increases linearly with vertical electric field. Support by the NSF and SRC-NRI Project 2204.001 (NSF-ECCS-1124733), FAME, one of six centers of STARnet, a SRC program sponsored by MARCO and DARPA and the use of XSEDE NSF Grant # OCI-1053575.

  7. Variation of surface sediments in the Dongho beach before and after the typhoon Kompasu in 2010, southwestern coast of Korea

    NASA Astrophysics Data System (ADS)

    Ryang, Woo Hun; So, Kwang-Suk

    2015-04-01

    The Dongho beach, located on the southwestern coast of Korea, is marco-tide, open-coast, and pocket-type. In the Dongho beach, this study has focused on the typhoon effects of topography, surface sediment, and sedimentary environment, appeared before and after the typhoon Kompasu in 2010. The typhoon Kompasu moved along the southwestern coasts and across midlands of the Korean Peninsula from 1 to 2 September in 2010. Coastal effect of the moving typhoon was investigated in terms of the surface variations of surface sediment facies and sedimentary environment. Surface topography and sediments before and after the typhoon (August - September 2010) were measured and sampled along the Dongho survey line of 23 sites, respectively. The surface topography in the mid-to-low tidal zone became low after the typhoon rather than that before the typhoon. The lower topographic change is indicative of surface sediment erosion caused by the typhoon wave. The pocket-type Dongho beach is mainly composed of fine to coarse sands, and the ratio of fine sand is the largest. The spatial distribution of surface sediments shows a coast-parallel band of fine and medium sands during three seasons of spring, fall, and winter, whereas medium sands dominated in the northern part of the study area during the summer. Before the typhoon, spatial distribution pattern of sedimentary facies showed a trend of coast-parallel bands of fine sand facies and medium sand facies, whereas that after the typhoon was partly different. Keywords: coastal effect, Typhoon Kompasu in 2010, surface sediment, macro-tide, beach Acknowledgements: This research was supported by the Korea Institute of Marine Science and Technology Promotion (KIMST) through the project grant of Tracking and Prediction on Impacts of Ancient Extreme Climatic Events in the West and South Coastal Zone of Korea and by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (2010-0025733).

  8. [The long way toward Mexican cardiology].

    PubMed

    de Mcheli, Alfredo

    2004-01-01

    The evolution of medical thought from the precientific phase during Renaissance toward the beginning of scientific phase in the XVII Century is reviewed. This phase was dominated by the great event of the discovery of blood circulation. The irradiation of this doctrine was parallel to that of Copernican theory. Harvey, the starter of experimental method in medicine, graduated at the University of Padua, where previously studied Copernicus. There he was influenced by Galileo's teaching, from whom adopted the quantitative focussing for his physiological research. His monograph Exercitatio anatomica de motu cordis... was present in Mexico, although it is not possible to establish when it arrived here. Only in the physiological treatise of doctor Marcos Joseph Salgado (1727) the blood circulation is described following Harvey's doctrine. Studies in the cardiovascular field began here during French intervention at the same time of the development of our Academy of Medicine. The first observations, concerning the blood vessels, were of surgical interest. Between 1870 and 1900, around 30 thesis related to cardiovascular system were presented at Mexican Medical School and various books related to this field were published. At the end of XIX century and in the beginning of the XX, some cardiovascular pharmacological investigations were done at the National Medical Institute under the direction of Dr. Fernando Altamirano. However only toward the middle of XX century it was possible to create and sistematize a cardiological specialty, thanks to the foresight of Dr. Ignacio Chávez. Cardiology today constitutes a mother discipline fragmented in a great number of subspecialities, each one having own characteristics, methodology and focussing. PMID:15259349

  9. Juniper Pollen Hotspots in the Southwest

    NASA Technical Reports Server (NTRS)

    Bunderson, L. D.; VandeWater, P.; Luvall, J.; Levetin, E.

    2013-01-01

    Rationale: Juniperus pollen is a major allergen in Texas, Oklahoma, and New Mexico. While the bulk of pollen may be released in rural areas, large amounts of pollen can be transported to urban areas. Major juniper species in the region include: Juniperus ashei, J. virginiana, J. pinchotii, and J. monosperma. Pollen release is virtually continuous beginning in late September with J. pinchotii and ending in May with J. monosperma. Urban areas in the region were evaluated for the potential of overlapping seasons in order to inform sensitive individuals. Methods: Burkard volumetric pollen traps were established for two consecutive spring seasons at 6 sites in northern New Mexico and 6 sites for two consecutive winter and fall seasons in Texas and Oklahoma Standard methods were used in the preparation and analysis of slides. Results: The Dallas-Fort Worth Metroplex is home to over 6 million people. It is adjacent to populations of J. pinchotii, J. virginiana, and J. ashei. Peak concentration near Dallas for J. ashei in 2011 was 5891 pollen grains/m3 in January 7th. The peak date for J. pinchotii at an upwind sampling location in San Marcos, TX was November 1, 2010 and peak for J. virginiana at a nearby station in Tulsa, OK was November 1, 2010 and peak for J. virginiana at a nearby station in Tulsa, OK was February 20, 2011. Amarillo, TX is adjacent to J. pinchotii, J. ashei, and J. monosperma populations and may be subject to juniper pollen from September through May. Conclusions: Considering the overlapping distributions of juniper trees and the overlapping temporal release of pollen, sensitive patients may benefit from avoiding hotspots.

  10. Hydroxypropyl-β-cyclodextrin spikes local inflammation that induces Th2 cell and T follicular helper cell responses to the coadministered antigen.

    PubMed

    Onishi, Motoyasu; Ozasa, Koji; Kobiyama, Kouji; Ohata, Keiichi; Kitano, Mitsutaka; Taniguchi, Keiichi; Homma, Tomoyuki; Kobayashi, Masanori; Sato, Akihiko; Katakai, Yuko; Yasutomi, Yasuhiro; Wijaya, Edward; Igarashi, Yoshinobu; Nakatsu, Noriyuki; Ise, Wataru; Inoue, Takeshi; Yamada, Hiroshi; Vandenbon, Alexis; Standley, Daron M; Kurosaki, Tomohiro; Coban, Cevayir; Aoshi, Taiki; Kuroda, Etsushi; Ishii, Ken J

    2015-03-15

    Cyclodextrins are commonly used as a safe excipient to enhance the solubility and bioavailability of hydrophobic pharmaceutical agents. Their efficacies and mechanisms as drug-delivery systems have been investigated for decades, but their immunological properties have not been examined. In this study, we reprofiled hydroxypropyl-β-cyclodextrin (HP-β-CD) as a vaccine adjuvant and found that it acts as a potent and unique adjuvant. HP-β-CD triggered the innate immune response at the injection site, was trapped by MARCO(+) macrophages, increased Ag uptake by dendritic cells, and facilitated the generation of T follicular helper cells in the draining lymph nodes. It significantly enhanced Ag-specific Th2 and IgG Ab responses as potently as did the conventional adjuvant, aluminum salt (alum), whereas its ability to induce Ag-specific IgE was less than that of alum. At the injection site, HP-β-CD induced the temporary release of host dsDNA, a damage-associated molecular pattern. DNase-treated mice, MyD88-deficient mice, and TBK1-deficient mice showed significantly reduced Ab responses after immunization with this adjuvant. Finally, we demonstrated that HP-β-CD-adjuvanted influenza hemagglutinin split vaccine protected against a lethal challenge with a clinically isolated pandemic H1N1 influenza virus, and the adjuvant effect of HP-β-CD was demonstrated in cynomolgus macaques. Our results suggest that HP-β-CD acts as a potent MyD88- and TBK1-dependent T follicular helper cell adjuvant and is readily applicable to various vaccines. PMID:25681338

  11. High-resolution analysis of salmonellae from turtles within a headwater spring ecosystem.

    PubMed

    Hahn, Dittmar; Gaertner, James; Forstner, Michael R J; Rose, Francis L

    2007-04-01

    Sediments and water from the pristine headwaters of the San Marcos River, Texas, USA, as well as swabs from biofilms on the carapace and from the cloacae of 17 musk turtles (Sternotherus odoratus) and one snapping turtle (Chelydra serpentina serpentina) caught at the same site, were analysed for salmonellae by culture and molecular techniques. Whereas enrichment cultures from sediment and water samples were negative for salmonellae in PCR- and in situ hybridization-based analyses, both techniques detected salmonellae after enrichments from both carapace and cloacae of nine (i.e. of 53%) musk turtles. Further characterization of 10 isolates obtained from the enrichment cultures of four selected individuals and confirmed as salmonellae by PCR analysis was achieved by fingerprinting techniques (rep-PCR). The results show differences between individuals and, in one case, variation among isolates from a single individual. All isolates from two individuals displayed identical profiles. These profiles were different from those obtained from the isolates of the third individual, which were, themselves, also identical for all isolates. Salmonellae were much more diverse in samples from the carapace of the last individual with five different rep-PCR profiles retrieved. Serotyping of seven isolates representative for each rep-PCR profile identified all isolates as representing Salmonella enterica subspecies enterica serotype Rubislaw, which demonstrates the presence of different strains of potentially human pathogenic salmonellae naturally occurring on turtles even within pristine environments. The frequent detection of these organisms in biofilms on the carapace opens the door for speculations on the role of this habitat as a reservoir for salmonellae, and on potential implications for turtles acting as a dispersal vector. PMID:17250751

  12. OPERATIONS REVIEW OF THE SAVANNAH RIVER SITE INTEGRATED SALT DISPOSITION PROCESS - 11327

    SciTech Connect

    Peters, T.; Poirier, M.; Fondeur, F.; Fink, S.; Brown, S.; Geeting, M.

    2011-02-07

    The Savannah River Site (SRS) is removing liquid radioactive waste from its Tank Farm. To treat waste streams that are low in Cs-137, Sr-90, and actinides, SRS developed the Actinide Removal Process and implemented the Modular Caustic Side Solvent Extraction (CSSX) Unit (MCU). The Actinide Removal Process contacts salt solution with monosodium titanate to sorb strontium and select actinides. After monosodium titanate contact, the resulting slurry is filtered to remove the monosodium titanate (and sorbed strontium and actinides) and entrained sludge. The filtrate is transferred to the MCU for further treatment to remove cesium. The solid particulates removed by the filter are concentrated to {approx} 5 wt %, washed to reduce the sodium concentration, and transferred to the Defense Waste Processing Facility for vitrification. The CSSX process extracts the cesium from the radioactive waste using a customized solvent to produce a Decontaminated Salt Solution (DSS), and strips and concentrates the cesium from the solvent with dilute nitric acid. The DSS is incorporated in grout while the strip acid solution is transferred to the Defense Waste Processing Facility for vitrification. The facilities began radiological processing in April 2008 and started processing of the third campaign ('MarcoBatch 3') of waste in June 2010. Campaigns to date have processed {approx}1.2 million gallons of dissolved saltcake. Savannah River National Laboratory (SRNL) personnel performed tests using actual radioactive samples for each waste batch prior to processing. Testing included monosodium titanate sorption of strontium and actinides followed by CSSX batch contact tests to verify expected cesium mass transfer. This paper describes the tests conducted and compares results from facility operations. The results include strontium, plutonium, and cesium removal, cesium concentration, and organic entrainment and recovery data. Additionally, the poster describes lessons learned during operation of the facility.

  13. Observacin y registro fotogrfico del cometa HYAKUTAKE C/1996 B2

    NASA Astrophysics Data System (ADS)

    Arquiola, A. P.; Arquiola, F. E.

    Desde el momento en que nos llega la informacin del descubrimiento, comenzamos la observacin de forma detallada a fin de apreciar y seguir su creciente actividad. La primera observacin se realiz el 17 de febrero de 1996 a las 4h20m UT con nuestro telescopio de 300mm newtoniano de f/6.5, con una muy buena transparencia atmosfrica, estimando una magnitud de 8.5. Realizbamos observaciones casi todas las noches, mientras nos lo permitan las condiciones climticas. Ya el 26 de febrero el cometa presentaba un aspecto muy particular, ligeramente distinto a las primeras observaciones, ya que comenzamos a notar su gran actividad. En primer lugar se destacaba la cola de iones mucho mas extensa que la cola de polvo. Magnitud estimada 7.5. El 19 de marzo ya era visible a simple vista y en especial su cola muy abierta y extensa (3 grados) y no quedaba duda alguna que la ltima noche de observacin del cometa en el horizonte de la Ciudad de Funes, que fue el 24 de marzo de 1996, un da antes del acercamiento a la Tierra, tendramos una apreciacin del cometa en su mximo esplendor. El 24 de marzo de 1996 a las 4hs UT, asom el cometa por el horizonte NE, con su cola espectacular, llegando a medir 23 grados de longitud, muy recta y brillante, y su cabellera muy estelar. A este marco de observacin se sumaron mas de 600 personas que participaron usando instrumentos, siendo la mayora de los concurrentes de la vecina Ciudad de Rosario, ya que su observacin era a muy baja atura sobre el horizonte norte. Instrumentos utilizados : Telescopio Newtoniano 300mm f/6.5, Telescopio Schmidt-Cassegrain 200mm , Binoculares 10 x 50, 7 x 50, Lente normal 50mm a f/1.8, Pelcula 100 - 400 ASA Lugar de Observacin : Ciudad de Funes, zona rural, ``Estancia La Polola" Latitud: - 32o 55' Longitud: 60o 40' Oeste

  14. Regional-to-Urban Enviro-HIRLAM Downscaling for Meteorological and Chemical Patterns over Chinese Megacities

    NASA Astrophysics Data System (ADS)

    Mahura, Alexander; Nuterman, Roman; Gonzalez-Aparicio, Iratxe; Amstrup, Bjarne; Baklanov, Alexander; Yang, Xiaohua; Nielsen, Kristian

    2015-04-01

    Due to strong economic growth in the past decades, air pollution became a serious problem in megacities and major industrial agglomerations of China. So, information on air quality in these urbanized areas is important for population. In particular, the metropolitan areas of Shanghai, Beijing, and Pearl River Delta are well known as main regions with serious air pollution issues. One of the aims of the EU FP7 MarcoPolo project is to improve existing regional-meso-urban/city scale air quality forecasts using improved emission inventories and to validate modelling results using satellite and ground-based measurements. The Enviro-HIRLAM (Environment - HIgh Resolution Limited Area Model) adapted for the Shanghai region of China is applied for forecasting. The model is urbanized using the Building Effects Parameterization module, which describes different types of urban districts such as industrial commercial, city center, high density and residential with its own characteristics. For sensitivity studies, the model was run in downscaling chain from regional-to-urban scales at subsequent horizontal resolutions of 15-5-2.5 km for selected dates with elevated pollution levels and unfavorable meteorological conditions. For these dates, the effects of urbanization are analyzed for atmospheric transport, dispersion, deposition, and chemical transformations. The evaluation of formation and development of meteorological and chemical/aerosol patterns due to influence of the urban areas is performed. The impact of selected (in a model domain) megacities of China is estimated on regional-to-urban scales, as well as relationship between air pollution and meteorology are studied.

  15. Atmospheric Processing Module for Mars Propellant Production

    NASA Technical Reports Server (NTRS)

    Muscatello, Anthony; Gibson, Tracy; Captain, James; Athman, Robert; Nugent, Matthew; Parks, Steven; Devor, Robert

    2013-01-01

    The multi-NASA center Mars Atmosphere and Regolith COllector/PrOcessor for Lander Operations (MARCO POLO) project was established to build and demonstrate a methane/oxygen propellant production system in a Mars analog environment. Work at the Kennedy Space Center (KSC) Applied Chemistry Laboratory is focused on the Atmospheric Processing Module (APM). The purpose of the APM is to freeze carbon dioxide from a simulated Martian atmosphere containing the minor components nitrogen, argon, carbon monoxide, and water vapor at Martian pressures (approx.8 torr) by using dual cryocoolers with alternating cycles of freezing and sublimation. The resulting pressurized CO2 is fed to a methanation subsystem where it is catalytically combined with hydrogen in a Sabatier reactor supplied by the Johnson Space Center (JSC) to make methane and water vapor. We first used a simplified once-through setup and later employed a HiCO2 recycling system to improve process efficiency. This presentation and paper will cover (1) the design and selection of major hardware items, such as the cryocoolers, pumps, tanks, chillers, and membrane separators, (2) the determination of the optimal cold head design and flow rates needed to meet the collection requirement of 88 g CO2/hr for 14 hr, (3) the testing of the CO2 freezer subsystem, and (4) the integration and testing of the two subsystems to verify the desired production rate of 31.7 g CH4/hr and 71.3 g H2O/hr along with verification of their purity. The resulting 2.22 kg of CH4/O2 propellant per 14 hr day (including O2 from electrolysis of water recovered from regolith, which also supplies the H2 for methanation) is of the scale needed for a Mars Sample Return mission. In addition, the significance of the project to NASA's new Mars exploration plans will be discussed.

  16. Atmospheric Processing Module for Mars Propellant Production

    NASA Technical Reports Server (NTRS)

    Muscatello, Anthony; Gibson, Tracy; Captain, James; Athman, Robert; Nugent, Matthew; Parks, Steven; Devor, Robert

    2013-01-01

    The multi-NASA center Mars Atmosphere and Regolith COllector/PrOcessor for Lander Operations (MARCO POLO) project was established to build and demonstrate a methane/oxygen propellant production system in a Mars analog environment. Work at the Kennedy Space Center (KSC) Applied Chemistry Laboratory is focused on the Atmospheric Processing Module (APM). The purpose of the APM is to freeze carbon dioxide from a simulated Martian atmosphere containing the minor components nitrogen, argon, carbon monoxide, and water vapor at Martian pressures (8 torr) by using dual cryocoolers with alternating cycles of freezing and sublimation. The resulting pressurized CO2 is fed to a methanation subsystem where it is catalytically combined with hydrogen in a Sabatier reactor supplied by the Johnson Space Center (JSC) to make methane and water vapor. We first used a simplified once-through setup and later employed a HiCO2 recycling system to improve process efficiency. This presentation and paper will cover (1) the design and selection of major hardware items, such as the cryocoolers, pumps, tanks, chillers, and membrane separators, (2) the determination of the optimal cold head design and flow rates needed to meet the collection requirement of 88 g CO2/hr for 14 hr, (3) the testing of the CO2 freezer subsystem, and (4) the integration and testing of the two subsystems to verify the desired production rate of 31.7 g CH4/hr and 71.3 g H20/hr along with verification of their purity. The resulting 2.22 kg of CH4/O2 propellant per 14 hr day (including O2 from electrolysis of water recovered from regolith, which also supplies the H2 for methanation) is of the scale needed for a Mars Sample Return mission. In addition, the significance of the project to NASA's new Mars exploration plans will be discussed.

  17. Worlds apart 2: Thailand and the Philippines. Heroes and villains in an Asian population drama.

    PubMed

    Ness, G D

    1994-01-01

    A comparison of population growth was made for the Philippines and Thailand. Although both countries had 20 million population in 1950 and developed family planning (FP) in similar stages, Thailand had a contraceptive use rate of about 65% and total fertility of 2.1 and a population of 57 million, while the Philippines had 7.4 million more people and slower economic development. Environmental effects of this situation in the Philippines included the movement of people to marginal mountainous land and soil erosion and degradation. A major medical problem has been complications from illegal abortion. While Thailand is expected to reach replacement level by 1995, the Philippines will not reach replacement level until at least 2015, by which time the population will be 20 million more than in Thailand. Thailand is experiencing declines in school age population, and the Philippines is experiencing growth in its school enrollment and labor force. Although the Philippines has received more foreign FP assistance than Thailand, the demographic impact has been greater in Thailand. The Philippines made mistakes in centralizing its FP efforts in Manila and spending too much on communication programs and less on service delivery in rural areas. After 1978, the emphasis shifted and funds were diminished for all social services by the Marcos regime. Mrs. Aguino could not right the wrongs of the previous administration because of her strong commitment to Roman Catholicism. The new Fidel Ramos administration and Health Secretary Flavier are now dedicated to promotion of primary health care and FP. Unfortunately, past political and religious leaders abnegated their responsibility in promoting responsible parenthood and providing appropriate social services. Instead these parties achieved personal wealth at the expense of the masses and protected a "dubious morality." PMID:12345835

  18. Scientific Packages on Small Bodies, a Deployment Strategy for New Missions

    NASA Astrophysics Data System (ADS)

    Tardivel, Simon; Scheeres, D. J.; Michel, P.

    2013-10-01

    The exploration of asteroids is currently a topic of high priority for the space agencies. JAXA will launch its second asteroid explorer, aimed at 1999 JU3, in the second half of 2014. NASA has selected OSIRIS-REx to go to asteroid Bennu, and it will launch in 2016. ESA is currently performing the assessment study of the MarcoPolo-R space mission, in the framework of the M3 (medium) competition of its Cosmic Vision Program, whose objective is now 2008 EV5. In the continuity of these missions, landing for an extended period of time on the ground to perform measurements seems a logical next step to asteroid exploration. Yet, the surface behavior of an asteroid is not well known and landing the whole spacecraft on it could be hazardous, and pose other mission operations problems such as ensuring communication with Earth. Hence, we propose a new approach to asteroid surface exploration. Using a mothership spacecraft, we will present how multiple landers could be deployed to the surface of an asteroid using ballistic trajectories. Combining a detailed simulation of the bouncing and contact dynamics on the surface with numerical and mathematical analysis of the flight dynamics near an asteroid, we show how landing pods could be distributed at the surface of a body. The strategy has the advantages that the mothership always maintains a safe distance from the surface and the landers do not need any GNC (guidance, navigation and control system) or landing apparatus. Thus, it allows for simple operations and for the design of lightweight landers with minimum platform overhead and maximum payload. These pods could then be used as a single measurement apparatus (e.g. seismometers) or as independent and different instruments, using their widespread distribution to gain both global and local knowledge on the asteroid.

  19. Hugoniot Measurements on Dry and Water-Saturated Soils

    NASA Astrophysics Data System (ADS)

    Newman, M.; Stewart, S. T.; Kraus, R. G.

    2012-12-01

    The shock response of soils is an important component of planetary cratering events, including deposition of ejecta blankets and secondary cratering. Here, we present a series of shock Hugoniot experiments on two types of soil samples in both dry and water-saturated states. We measured the shock states induced via planar impact experiments on the Harvard 40-mm gas gun. Shock wave velocities in the soil samples were measured using both VISAR and piezoelectric pins. A Monte Carlo technique was developed to accurately propagate formal error through the impedance match calculations and generate a 1-sigma error ellipse in shock-velocity (US) vs. particle velocity (up) space and pressure vs. volume space. The two soils were composed primarily of quartz with different mass fractions of phyllosilicates and amorphous material. Using initial particle sizes ranging from 150 to 300 microns, the samples were pressed to densities ranging from 1.89 to 1.93 g~cm-3 (about 25% porous). Water-saturated samples had densities ranging from 2.2 to 2.6 g~cm-3. We find that the dry soils have a linear US-u_p relation that is similar to dry quartz sand with the same initial density. The water-saturated samples are less compressible and have much greater scatter in shock velocities. The VISAR measurement records the dispersion around the mean shock state that arises from reflections between grains, and we compare the VISAR data to meso-scale hydrocode simulations of the experiment. These data will be used to generate more accurate rheological models for hydrocode simulations of the shock response of heterogeneous granular materials in the low-pressure regime (<10~GPa). We thank Marcos Hankin and Will Steinhardt for their technical support. We acknowledge support from Army Research Office grant #W911NF-10-1-037.

  20. Sobre o uso das séries de Puiseux em mecanica celeste

    NASA Astrophysics Data System (ADS)

    Miloni, O. I.

    2003-08-01

    Neste trabalho é apresentada uma demonstração do uso dos diferentes desenvolvimentos em séries para as equações de perturbação em Mecânica Celeste no marco Hamiltoniano. Em trabalhos clássicos como os de Poincaré (Poincaré, 1893) por exemplo, já esta planteado o uso de potências não inteiras no pequeno parâmetro, o que evidencia a não analiticidade das funções quando uma ressonância ocorre. Nestes trabalhos os desenvolvimentos são na raíz quadrada da massa de Júpiter (o pequeno parâmetro). Mais recentemente (Ferraz-Mello, 1985) outros tipos de desenvolvimentos foram aplicados modificando substancialmente as ordens de grandeza e a velocidade de convergência das séries. Com esta abordagem, os desenvolvimentos foram expressados em termos da raíz cúbica do pequeno parâmetro. Neste trabalho apresentamos um enfoque geral, onde os diferentes tipos de desenvolvimentos em séries de Puiseux (Valiron, 1950) são obtidos a partir da aplicação de Teorema de Preparação de Weierstrass (Goursat, 1916) considerando a equação de Hamilton-Jacobi como uma equação algébrica. Os resultados são aplicados ao problema restrito dos três corpos em ressonância de primeira ordem e, dependendo da grandeza da excentricidade do asteróide em relação à de Júpiter, obtemos os diferentes desenvolvimentos, em raíz quadrada ou raíz cúbica da massa de Júpiter.