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1

Dan Marino Helping Those with Autism Spectrum Disorders | NIH MedlinePlus the Magazine  

MedlinePLUS

... Marino Foundation. Photo: Dan Marino Foundation Former NFL star quarterback Dan Marino and his wife Claire experienced ... to succeed in life,'" says the former NFL star. "That's where the focus for The Dan Marino ...

2

Fifth Siglo de Oro Drama Festival  

E-print Network

SPRING 1980 79 Fifth Siglo de Oro Drama Festival ARTURO PEREZ and ROBERTO RODRÍGUEZ El festival de Teatro del Siglo de Oro, que en 1976 comenzó siendo un laudable esfuerzo por la difusión de la cultura hispánica, se ha convertido, en el... transcurso de unos pocos años, en el evento cultural de carácter internacional más relevante del Suroeste de los Estados Unidos. Dicho Festival, organizado por el Servicio Nacional de Parques y auspiciado por el Departamento del In terior de EE.UU., ha...

Pé rez, Arturo; Rodriguez, Roberto R.

1980-04-01

3

III Festival del Siglo de Oro (Chamizal)  

E-print Network

SPRING 1978 111 III Festival del Siglo de Oro (Chamizal) E. JARABA-PARDO El Siglo de Oro fue, por la fecundidad de los autores y por las influencias trascendentales de sus obras en el posterior desarrollo de la dramaturgia universal, uno de los... períodos más importantes en la historia del teatro. Algunos de sus rasgos esenciales fueron el uso de un lenguaje popular, satírico, e irónico, la introducción de personajes de las clases bajas, tales como esclavos y sirvientes, y la irreverencia a las...

Jaraba-Pardo, E.

1978-04-01

4

Chamizal Siglo de Oro Festival (March 1977)  

E-print Network

44 LATIN AMERICAN THEATRE REVIEW Chamizal Siglo de Oro Festival (March 1977) From March 15-25, the Chamizal National Memorial in El Paso hosted its second Siglo de Oro Drama Festival. Academic and repertory groups from New York, North Carolina... States and out of a series of colloquies grew the idea of such a festival. With co-sponsorship from the El Paso Bicentennial Commission, the first festival was held last year. Because of the wide critical acclaim and enthusiastic audiences, the gala...

Reid, Walker

1977-10-01

5

Oros controlled-release formulations of metoprolol  

PubMed Central

1 A combined biopharmaceutical and haemodynamic approach to the development of a metoprolol Oros controlled-release delivery system for once daily administration is reported. 2 Two studies, each involving 18 healthy volunteers, were performed in which twice daily administration of 100 mg conventional metoprolol tartrate tablets was compared with once daily administration of Oros systems containing 190 mg metoprolol fumarate but with different drug release rates. Plasma drug concentrations and ?-adrenoceptor blocking effects were measured over 24 h on days 1 and 5 of each treatment, and pre-dose in the interval between the main study days. 3 The results of the first study with a 19 mg/h Oros system indicated that this rate was too rapid to provide the required response under steady-state dosing conditions. Theoretical calculations based on a one-compartment pharmacokinetic model and input functions for hypothetical Oros systems were then performed to define the optimal release rate for a once daily preparation. 4 The results of the second study confirmed that a 14 mg/h system possessed the required characteristics in that it maintained more uniform ?-adrenoceptor blockade throughout 24 h, and produced pre-dosing plasma concentrations and haemodynamic effects which were identical to those for the conventional tablet twice daily regimen. PMID:4005128

Good, W.; Leeson, L. J.; Zak, S. L.; Wagner, W. E.; Meeker, J. B.; Arnold, J. D.

1985-01-01

6

Knowledge, attitude, and practices regarding oro-facial injuries and oro-facial protective devices among physical instructors in Bangalore  

PubMed Central

Background: Sports specific dental injuries are seen to occur frequently among children and young athletes. Dental injury is a distressing event often causing psychological as well as physical problems. The risk of children getting dental injuries during sports activities can be minimized by using a mouth guard and other oro-facial protective devices. The aim of this study is to determine the knowledge, attitude and practices of physical instructors in Bangalore, regarding oro-facial injuries and orofacial protective devices. Material & Methods: A self-completion questionnaire was sent to 50 physical instructors of schools, sports academies and gymnasiums situated in the South of Bangalore city. The questionnaire sought information about the knowledge of the incidence of oro-facial injuries, common sports causing oro-facial injuries and oro-facial protective devices and their role in the prevention of injuries. The data was subjected to statistical analysis. Results: The population under study comprised of 92 males and 8 females. About 38% of oro-facial injuries were reported by physical instructors in the previous year. Physical instructors had knowledge regarding oro-facial protective devices like mouth guards (54%) and helmet (40%). The attitude and practice regarding the usage of mouth guards was found to be minimal. Conclusion: The physical instructors had knowledge especially through the media on the protective effectiveness of mouth guards in reducing the oro facial injuries. Despite their awareness, only 4% of them recommended the mandatory use of the mouth guards. Majority of them could not recommend its usage as they were unaware of its availability and the reason for not using the mouth is its improper fitting. How to cite the article: Neeraja G, Bharadwaj S, Shah K, Subramaniam P. Knowledge, attitude, and practices regarding oro-facial injuries and oro-facial protective devices among physical instructors in Bangalore. J Int Oral Health 2014;6(3):1-6. PMID:25083024

Neeraja, G; Bharadwaj, Srivats; Shah, Kinjal; Subramaniam, Priya

2014-01-01

7

DOE/ORO/2261 Oak Ridge Reservation Annual Site  

E-print Network

......................... 1-11 1.4.3 Oak Ridge National Laboratory Ridge National Laboratory East Tennessee Technology Park Electronic publisher Coordinating editor, Jane Parrott Project manager, DOE-ORO David Page September 2008 Prepared by Oak Ridge National

Pennycook, Steve

8

El Sexto Festival de Teatro Español del Siglo de Oro  

E-print Network

SPRING 1981 79 El Sexto Festival de Teatro Español del Siglo de Oro Arturo Pérez-Pisonero El Sexto Festival de Teatro Español del Siglo de Oro, celebrado en el Chamizal National Memorial en las fechas del 6 al 22 de marzo, ha presen tado, como... en años anteriores, un muy variado programa de grupos profe sionales y aficionados. La nutrida participación ha demostrado, en muchos casos, más entusiasmo que habilidad por parte de directores y actores para resolver la compleja problemática que...

Pé rez-Pisonero, Arturo

1981-04-01

9

Department of Energy (DOE) Oak Ridge Office (ORO) Project Life  

E-print Network

Department of Energy (DOE) Oak Ridge Office (ORO) Project Life Cycle Reimbursable Funding: http://www.ornl.gov/wfo/exthome.htm October 11, 2010 #12;OAK RIDGE NATIONAL LABORATORY U. S. DEPARTMENT Project Closeout Process Summary #12;OAK RIDGE NATIONAL LABORATORY U. S. DEPARTMENT OF ENERGY 3 Secretary

10

Department of Energy (DOE) Oak Ridge Office (ORO) Project Life  

E-print Network

Department of Energy (DOE) Oak Ridge Office (ORO) Project Life Cycle Reimbursable Funding://www.ornl.gov/wfo/exthome.htm September 27, 2007 #12;2 OAK RIDGE NATIONAL LABORATORY U. S. DEPARTMENT OF ENERGY Briefing Outline · Summary #12;3 OAK RIDGE NATIONAL LABORATORY U. S. DEPARTMENT OF ENERGY Secretary of Energy Legal Authority

11

DOE/ORO/2296 Oak Ridge Reservation Annual Site  

E-print Network

Project manager, DOE-ORO David Page September 2009 Prepared by Oak Ridge National Laboratory P.O. Box 2008 .......................... 1-13 1.4.3 Oak Ridge National Laboratory Ridge National Laboratory East Tennessee Technology Park Electronic publisher Coordinating editor

Pennycook, Steve

12

Multiple sclerosis in the Republic of San Marino.  

PubMed Central

Previous studies on the prevalence of multiple sclerosis in Italy have grossly underestimated the prevalence of the disease. The prevalence in the Republic of San Marino (near Rimini), in Sicily, and no doubt in the rest of Italy, is of the same order of magnitude as in Europe--that is, 40-60/100 000. The contrast of this with the very low prevalence in Malta (only 60 miles (96 km) away from Sicily) of 4/100 000 should provide a clue to the genetic and environmental factors responsible for multiple sclerosis. PMID:6707559

Morganti, G; Naccarato, S; Elian, M; Ferrari, P; Kelly, R; Karhausen, L; Dean, G

1984-01-01

13

Oro-facial granulomatosis: a possible allergic basis.  

PubMed

Food or flavouring intolerance has been demonstrated in 14 out of 80 patients with oro-facial granulomatosis. Provoking molecules include cinnamaldehyde, carvone and piperitone, although a wide range of food or flavourings may be implicated. The nature of the reaction is not understood but does not seem to involve an IgE mediated response. At present the only reliable way of detecting specific provoking factors is by the use of an elimination diet. PMID:2931101

Patton, D W; Ferguson, M M; Forsyth, A; James, J

1985-08-01

14

Non-surgical pneumoperitoneum after oro-genital intercourse?  

PubMed Central

INTRODUCTION In many cases, a pneumoperitoneum is due to air escaping from a perforated hollow viscus or surgical intervention but there are increasing reports of non-surgical causes. PRESENTATION OF CASE We report a case where a pneumoperitoneum was identified after oro-genital sexual intercourse. DISCUSSION There were nineteen reported cases of non-surgical pneumoperitoneum from gynaecologic causes up to May 2013. We report an additional case four hours after oro-genital intercourse. Close clinical observation and symptomatic treatment are usually all that is required but operative interventions should be considered if the patient develops abdominal pain, peritoneal signs, fever or leukocytosis during observation. CONCLUSION This adds to the world literature on non-surgical pneumoperitoneum from oro-genital intercourse. Clinicians should be aware of this condition and focus on medical-sexual history as this information could prevent a patient from being exposed to expensive diagnostics and invasive operative treatments. Patients should also be educated about the mechanisms to avoid future possible diagnostic dilemmas. PMID:24121052

Cawich, Shamir O.; Johnson, Peter B.; Williams, Eric; Naraynsingh, Vijay

2013-01-01

15

A possible cranio-oro-facial phenotype in Cockayne syndrome  

PubMed Central

Background Cockayne Syndrome CS (Type A – CSA; or CS Type I OMIM #216400) (Type B – CSB; or CS Type II OMIM #133540) is a rare autosomal recessive neurological disease caused by defects in DNA repair characterized by progressive cachectic dwarfism, progressive intellectual disability with cerebral leukodystrophy, microcephaly, progressive pigmentary retinopathy, sensorineural deafness photosensitivity and possibly orofacial and dental anomalies. Methods We studied the cranio-oro-facial status of a group of 17 CS patients from 15 families participating in the National Hospital Program for Clinical Research (PHRC) 2005 « Clinical and molecular study of Cockayne syndrome ». All patients were examined by two investigators using the Diagnosing Dental Defects Database (D[4]/phenodent) record form. Results Various oro-facial and dental anomalies were found: retrognathia; micrognathia; high- arched narrow palate; tooth crowding; hypodontia (missing permanent lateral incisor, second premolars or molars), screwdriver shaped incisors, microdontia, radiculomegaly, and enamel hypoplasia. Eruption was usually normal. Dental caries was associated with enamel defects, a high sugar/carbohydrate soft food diet, poor oral hygiene and dry mouth. Cephalometric analysis revealed mid-face hypoplasia, a small retroposed mandible and hypo-development of the skull. Conclusion CS patients may have associated oro-dental features, some of which may be more frequent in CS children – some of them being described for the first time in this paper (agenesis of second permanent molars and radiculomegaly). The high susceptibility to rampant caries is related to a combination of factors as well as enamel developmental defects. Specific attention to these anomalies may contribute to diagnosis and help plan management. PMID:23311583

2013-01-01

16

The Oro Grande, New Mexico, chondrite and its lithic inclusion.  

NASA Technical Reports Server (NTRS)

The Oro Grande, New Mexico, U.S.A., chondrite was found in 1971. Electron microprobe analyses and microscopic examination show the following mineralogy: olivine (Fa 19.3 mole %), orthopyroxene (Fs 16.2 mole %), diopside, feldspar (An 13.6 mole %), chlorapatite, whitlockite, kamacite, taenite, troilite, chromite, and an iron-bearing terrestrial weathering product. A bulk chemical analysis of the meteorite shows the following results (weight %): Fe 0.84, Ni 1.46, Co 0.07, FeS 3.62, SiO2 34.18, TiO2 0.14, Al2O3 1.83, Cr2O3 0.55, Fe2O3 21.25, FeO 9.13, MnO 0.31, MgO 21.52, CaO 1.72, Na2O 0.70, K2O 0.08, P2O5 0.25, H2O(+) 2.14, H2O(-) 0.40, C 0.22, sum 100.41. On the basis of composition and texture the Oro Grande meteorite is classified as an H5 chondrite.

Fodor, R. V.; Keil, K.; Jarosewich, E.

1972-01-01

17

Oro-facial gangrene (noma/cancrum oris): pathogenetic mechanisms.  

PubMed

Cancrum oris (Noma) is a devastating infectious disease which destroys the soft and hard tissues of the oral and para-oral structures. The dehumanizing oro-facial gangrenous lesion affects predominantly children ages 2 to 16 years, particularly in sub-Saharan Africa, where the estimated frequency in some communities varies from 1 to 7 cases per 1000 population. The risk factors are poverty, malnutrition, poor oral hygiene, residential proximity to livestock in unsanitary environments, and infectious diseases, particularly measles and those due to the herpesviridae. Infections and malnutrition impair the immune system, and this is the common denominator for the occurrence of noma. Acute necrotizing gingivitis (ANG) and oral herpetic ulcers are considered the antecedent lesions, and ongoing studies suggest that the rapid progression of these precursor lesions to noma requires infection by a consortium of micro-organisms, with Fusobacterium necrophorum (Fn) and Prevotella intermedia (Pi) as the suspected key players. Additional to production of a growth-stimulating factor for Pi, Fn displays a classic endotoxin, a dermonecrotic toxin, a cytoplasmic toxin, and a hemolysin. Without appropriate treatment, the mortality rate from noma is 70-90%. Survivors suffer the two-fold afflictions of oro-facial mutilation and functional impairment, which require a time-consuming, financially prohibitive surgical reconstruction. PMID:12002813

Enwonwu, C O; Falkler, W A; Idigbe, E O

2000-01-01

18

The San Marino Scale: A new analytical tool for assessing transmission risk  

Microsoft Academic Search

Nearly everyone is familiar with the Richter Scale for quantifying earthquake severity. Can we similarly quantify the potential hazard of active SETI, that is, transmitting signals into space from Earth? The San Marino Scale is an attempt to do just that. It is an ordinal scale between 1 and 10, used to quantify the potential risk of employing electromagnetic communications

Iván Almár; H. Paul Shuch

2007-01-01

19

Bridging the Gap Between Theory and Hardware Mario Marino, Gabriel Robins, Kevin Skadron, and Liang Wang  

E-print Network

of automatically translating theoretical computation models into an implementation-ready hardware description computational models, such as the Bounded-Error Quantum Polynomial-Time model employed in quantum computing [2Bridging the Gap Between Theory and Hardware Mario Marino, Gabriel Robins, Kevin Skadron, and Liang

Skadron, Kevin

20

Prostate Visualization with Overlapping Regions of Interest Joseph Marino Arie Kaufman  

E-print Network

Prostate Visualization with Overlapping Regions of Interest Joseph Marino Arie Kaufman Stony Brook of prostate MRI data and CAD results, referred to as score values. In this system, it is also possible--Interaction techniques 1 INTRODUCTION Prostate cancer is one of the most prevalent cancers worldwide [4]. Recently

21

Una tarde con Héctor Mendoza  

E-print Network

hay más. Mira, realmente, les voy a contar. Lo que me sucede ahora es que me he preocupado terriblemente por la teoría de la actuación, y lo que estoy haciendo son textos teóricos sobre la actuación. Ahora lo que hago es una obra mezclada con la... teoría de la actuación. Siento que tomar un texto de los Siglos de Oro, que son textos que ya me son muy familiares, entonces, se me facilita muchísimo más para su manejo; en este sentido, ¿no? Ahora, yo siento que se me facilita también tomar un texto...

Padró n-Leó n, Bá rbara A.; Peale, C. George

1999-10-01

22

ADHD Treatment with Once-Daily OROS Methylphenidate: Final Results from a Long-term Open-Label Study  

ERIC Educational Resources Information Center

Objective: Few studies have assessed effectiveness and tolerability of stimulants when used for prolonged periods in children with attention-deficit/hyperactivity disorder (ADHD). This article presents final results from an open-label, multisite study of a once-daily formulation of methylphenidate (MPH), OROS[R] MPH. Method: Subjects received OROS…

Wilens, Timothy; McBurnett, Keith; Stein, Mark; Lerner, Marc; Spencer, Thomas; Wolraich, Mark

2005-01-01

23

Management of Oro-Nasal Fistula Using Andrew's Bridge: A Case Report.  

PubMed

Oro-nasal fistula is the most common complication following the surgical closure of the cleft palate. Retention is the paramount factor in the successful prosthodontic habilitation of cleft palate patients. Various precision attachments have provided us with the opportunity to make the prosthesis fixed removable type; giving a double advantage to the patient i.e. comfort through fixed type and easy maintenance through removal type. This case report describes a case of oro-nasal fistula habilitated with an obturator attached to Andrew's bridge, which had good retention and esthetics. PMID:25183920

Harish, P V; Bhojaraju, Nandakishore; Sowmya, G R; Gangaiah, Makam

2014-09-01

24

Pharmacokinetic investigation of the absorption of oxprenolol from Oros delivery systems in healthy volunteers  

PubMed Central

1 The absorption kinetics of oxprenolol have been investigated in eight healthy volunteers after single dosing with 16/260 Oros drug delivery systems. Oxprenolol disposition kinetics in individual subjects were estimated from intravenous dose data. 2 Loo-Riegelman analysis of the plasma concentration data indicated an extended duration of drug absorption for the Oros system. Initially, the in vivo absorption rate was similar to the in vitro release rate but after 5-6 h it slowed perceptibly. However, at later times similar in vivo and in vitro rates were again observed. 3 The absolute bioavailabilities for prototype and clinical trial systems were shown to be similar, at approximately 42%, and no significant differences in plasma profiles or pharmacokinetic constants were detected between the two Oros forms. 4 A comparison of plasma concentration data in seven subjects who received the prototype system on two occasions in separate studies indicated a consistent level of drug absorption from this preparation. 5 Approximately 10-15% of the administered dose was found in Oros systems recovered from faeces. The quantity of drug remaining was poorly correlated with the observed areas under the plasma concentration-time curve. PMID:4005118

Bradbrook, I. D.; John, V. A.; Morrison, P. J.; Rogers, H. J.; Spector, R. G.

1985-01-01

25

Time Course of Treatment Effect of OROS[R] Methylphenidate in Children with ADHD  

ERIC Educational Resources Information Center

Objective: The authors evaluated the time course of the treatment effect of Osmotic-Release Oral System methylphenidate (OROS[R] MPH) HCl (Concerta[R], Raritan, NJ) CII in children with ADHD. Method: Data were combined from two double-blind, randomized, placebo-controlled, cross-over, analog classroom studies in children (9-12 years) with ADHD.…

Armstrong, Robert B.; Damaraju, C. V.; Ascher, Steve; Schwarzman, Lesley; O'Neill, James; Starr, H. Lynn

2012-01-01

26

Non-Speech Oro-Motor Exercise Use in Acquired Dysarthria Management: Regimes and Rationales  

ERIC Educational Resources Information Center

Background: Non-speech oro-motor exercises (NSOMExs) are described in speech and language therapy manuals and are thought to be much used in acquired dysarthria intervention, though there is no robust evidence of an influence on speech outcome. Opinions differ as to whether, and for which dysarthria presentations, NSOMExs are appropriate. Aims:…

Mackenzie, Catherine; Muir, Margaret; Allen, Carolyn

2010-01-01

27

OroSTIFF: Face-referenced measurement of perioral stiffness in health and disease  

PubMed Central

A new device and automated measurement technology known as OroSTIFF is described to characterize non-participatory perioral stiffness in healthy adults for eventual application to patients with orofacial movement disorders associated with neuromotor disease, traumatic injury, or congenital clefts of the upper lip. Previous studies of perioral biomechanics required head stabilization for extended periods of time during measurement which precluded sampling patients with involuntary body/head movements (dyskinesias), or pediatric subjects. The OroSTIFF device is face-referenced and avoids the complications associated with head-restraint. Supporting data of non-participatory perioral tissue stiffness using OroSTIFF are included from 10 male and 10 female healthy subjects. The OroSTIFF device incorporates a pneumatic glass air cylinder actuator instrumented for pressure, and an integrated subminiature displacement sensor to encode lip aperture. Perioral electromyograms were simultaneously sampled to confirm passive muscle state for the superior and inferior divisions of the orbicularis oris muscles. Perioral stiffness, derived as a quotient from resultant force (?F) and interangle span (?X), was modeled with multilevel regression techniques. Real-time calculation of the perioral stiffness function demonstrated a significant quadratic relation between imposed interangle stretch and resultant force. This stiffness growth function also differed significantly between males and females. This study demonstrates the OroSTIFF ‘proof-of-concept’ for cost-effective non-invasive stimulus generation and derivation of perioral stiffness in a group of healthy unrestrained adults, and a case study to illustrate the dose-dependent effects of Levodopa on perioral stiffness in an individual with advanced Parkinson’s disease who exhibited marked dyskinesia and rigidity. PMID:20185131

Chu, Shin-Ying; Kieweg, Douglas; Lee, Jaehoon

2010-01-01

28

Long-term efficacy and safety outcomes with OROS-MPH in adults with ADHD  

PubMed Central

Methylphenidate (MPH) is widely prescribed for adults with attention deficit hyperactivity disorder (ADHD), but data on long-term treatment and maintenance of effect are lacking. Osmotic release oral system-methylphenidate (OROS–MPH) was evaluated in a 52-wk open-label study in subjects who had previously completed a short-term placebo-controlled trial and short-term open-label extension. Efficacy was assessed using the investigator- and subject-rated Conners’ Adult ADHD Rating Scales (CAARS:O-SV and CAARS:S-S), and the Clinical Global Impression – Severity (CGI-S), Sheehan Disability Scale (SDS) and Quality of Life Enjoyment and Satisfaction Questionnaire (Q-LES-Q). Subjects completing ?52 wk of treatment were eligible for a 4-wk randomized, placebo-controlled withdrawal phase in which loss of treatment effect was assessed using CAARS:O-SV and CGI-S. In the open-label phase (n=156), mean CAARS:O-SV score decreased from baseline by 1.9±7.8 (p<0.01), and small, statistically significant improvements from baseline were observed for CAARS:S-S, CGI-S and SDS. In the double-blind phase (OROS-MPH, n=23; placebo, n=22), CAARS:O-SV increased from double-blind baseline in the OROS-MPH and placebo arms (4.0±7.6 vs. 6.5±7.8, not statistically significant). Long-term OROS-MPH treatment was well tolerated, and there was no evidence of withdrawal or rebound after discontinuation. In conclusion, the short-term benefits of OROS-MPH continue during long-term open-label treatment. Maintenance of efficacy in a placebo-controlled withdrawal design remains to be confirmed in larger patient populations. PMID:21798108

Buitelaar, Jan K.; Trott, Götz-Erik; Hofecker, Maria; Waechter, Sandra; Berwaerts, Joris; Dejonkheere, Joachim; Schäuble, Barbara

2012-01-01

29

Multicenter, randomized, open-label study of OROS methylphenidate versus atomoxetine: treatment outcomes in African-American children with ADHD.  

PubMed Central

The Formal Observation of Concerta versUs Strattera (FOCUS) study was conducted to assess, in children with ADHD, treatment outcomes with Concerta [OROS methylphenidate (MPH)], a once-daily controlled-release medication, and Strattera, (atomoxetine), a selective noradrenaline reuptake inhibitor, Because of the lack of data in minority groups treated for ADHD, the present subgroup analysis was conducted to determine the effectiveness and tolerability of ADHD treatments in African-American patients who were randomized to OROS MPH (n=125) or atomoxetine (n=58) during the FOCUS study. At the end of the study, the mean dose of OROS MPH was 32.8 +/- 10.9 mg and that of atomoxetine was 1.1 +/- 0.4 mg/kg. The results demonstrated that both treatments were associated with significant improvements in ADHD symptoms from baseline; however, patients who received OROS MPH demonstrated significantly greater improvements in total ADHD symptoms, inattentiveness and global improvement. The incidence of adverse events was similar in both treatment groups. OROS MPH and atomoxetine are effective and tolerable in the treatment of African Americans with ADHD, and significantly greater treatment responses were observed in patients receiving OROS MPH compared with those receiving atomoxetine over three weeks. Additional studies are needed to evaluate treatment response in this population. PMID:16350601

Starr, H. Lynn; Kemner, Jason

2005-01-01

30

An update on pathophysiological mechanisms related to idiopathic oro-facial pain conditions with implications for management.  

PubMed

Chronic oro-facial pain conditions such as persistent idiopathic facial pain (PIFP), atypical odontalgia (AO) and burning mouth syndrome (BMS), usually grouped together under the concept of idiopathic oro-facial pain, remain a diagnostic and therapeutic challenge. Lack of understanding of the underlying pathophysiological mechanisms of these pain conditions is one of the important reasons behind the problems in diagnostic and management. During the last two decades, neurophysiological, psychophysical, brain imaging and neuropathological methods have been systematically applied to study the trigeminal system in idiopathic oro-facial pain. The findings in these studies have provided evidence for neuropathic involvement in the pathophysiology of PIFP, AO and BMS. The present qualitative review is a joint effort of a group of oro-facial pain specialists and researchers to appraise the literature on idiopathic oro-facial pain with special focus on the currently available studies on their pathophysiological mechanisms. The implications of the findings of these studies for the clinical diagnosis and treatment of idiopathic oro-facial pain conditions are discussed. PMID:25483941

Forssell, H; Jääskeläinen, S; List, T; Svensson, P; Baad-Hansen, L

2014-12-01

31

Referral delay in diagnosis of oro\\/oropharyngeal cancer in Israel  

Microsoft Academic Search

The delay, stage at diagnosis and referral pattern of 543 oro\\/oropharyngeal cancer patients in Israel were investigated. About two-thirds of the malignancies were diagnosed at early stages. In more than two-thirds there was a delay of at least 2 months from the onset of signs and symptoms up to diagnosis, with a non-significant relationship between stage and delay. A significant

M. Gorsky; D. Dayan

1995-01-01

32

Fore arc tectonothermal evolution of the El Oro metamorphic province (Ecuador) during the Mesozoic  

NASA Astrophysics Data System (ADS)

El Oro metamorphic province of SW Ecuador is a composite massif made of juxtaposed terranes of both continental and oceanic affinity that has been located in a fore-arc position since Late Paleozoic times. Various geochemical, geochronological, and metamorphic studies have been undertaken on the El Oro metamorphic province, providing an understanding of the origin and age of the distinct units. However, the internal structures and geodynamic evolution of this area remain poorly understood. Our structural analysis and thermal modeling in the El Oro metamorphic province show that this fore-arc zone underwent four main geological events. (1) During Triassic times (230-225 Ma), the emplacement of the Piedras gabbroic unit at crustal-root level (~9 kbar) triggered partial melting of the metasedimentary sequence under an E-W extensional regime at pressure-temperature conditions ranging from 4.5 to 8.5 kbar and from 650 to 900°C for the migmatitic unit. (2) At 226 Ma, the tectonic underplating of the Arenillas-Panupalí oceanic unit (9 kbar and 300°C) thermally sealed the fore-arc region. (3) Around the Jurassic-Cretaceous boundary, the shift from trench-normal to trench-parallel subduction triggered the exhumation and underplating of the high-pressure, oceanic Raspas Ophiolitic Complex (18 kbar and 600°C) beneath the El Oro Group (130-120 Ma). This was followed by the opening of a NE-SW pull-apart basin, which tilted the massif along an E-W subhorizontal axis (110 Ma). (4) In Late Cretaceous times, an N-S compressional event generated heterogeneous deformation due to the presence of the Cretaceous Celica volcanic arc, which acted as a buttress and predominantly affected the central and eastern part of the massif.

Riel, Nicolas; Martelat, Jean-Emmanuel; Guillot, Stéphane; Jaillard, Etienne; Monié, Patrick; Yuquilema, Jonatan; Duclaux, Guillaume; Mercier, Jonathan

2014-10-01

33

Left Hemisphere Specialization for Oro-Facial Movements of Learned Vocal Signals by Captive Chimpanzees  

PubMed Central

Background The left hemisphere of the human brain is dominant in the production of speech and signed language. Whether similar lateralization of function for communicative signal production is present in other primates remains a topic of considerable debate. In the current study, we examined whether oro-facial movements associated with the production of learned attention-getting sounds are differentially lateralized compared to facial expressions associated with the production of species-typical emotional vocalizations in chimpanzees. Methodology/ Principal Findings Still images captured from digital video were used to quantify oro-facial asymmetries in the production of two attention-getting sounds and two species-typical vocalizations in a sample of captive chimpanzees. Comparisons of mouth asymmetries during production of these sounds revealed significant rightward biased asymmetries for the attention-getting sounds and significant leftward biased asymmetries for the species-typical sounds. Conclusions/Significance These results suggest that the motor control of oro-facial movements associated with the production of learned sounds is lateralized to the left hemisphere in chimpanzees. Furthermore, the findings suggest that the antecedents for lateralization of human speech may have been present in the common ancestor of chimpanzees and humans ?5 mya and are not unique to the human lineage. PMID:18575610

Reynolds Losin, Elizabeth A.; Russell, Jamie L.; Freeman, Hani; Meguerditchian, Adrien; Hopkins, William D.

2008-01-01

34

Efficacy and tolerability of OROS methylphenidate in Korean children with attention-deficit/hyperactivity disorder.  

PubMed

This study evaluated the efficacy and tolerability in the initiation treatment of Concerta (OROS methylphenidate HCl) in Korean children with Attention-Deficit/Hyperactivity Disorder (AD/HD). One hundred and nineteen children with AD/HD were entered into a multi-center, open-label, four-week trial. The dosage of Concerta was adjusted by the investigators based on symptoms and safety assessments performed on a weekly basis. The safety of the drug and its efficacy for attention, behavior, and cognitive function were assessed. The primary outcome measures for efficacy were the Parent and Teacher IOWA Conners Rating Scales, Peer Interaction Items, and the Clinical Global Impression Scale. Cognitive tests (Continuous Performance Test, Matched Familiar Figure Test, Verbal Fluency Test, and Trail Making Test) were included as the secondary outcome measures. In most participants, OROS methylphenidate was well tolerated. There were significant improvements in attention, behavior, and function as measured by parents, teachers, and investigators. The benefit of the initiation of OROS methylphenidate in children with AD/HD was shown on the cognitive tests as well. These data provide support for the benefit of the once-daily methylphenidate preparation, Concerta in the treatment of Korean children with AD/HD. Children were initiated safely in this short-term trial, and its effectiveness was evident in the behavioral, as well as neuropsychological measurements. PMID:17046131

Lee, Soyoung Irene; Hong, Sungdo David; Kim, Sang-Yeup; Kim, Eui-Jung; Kim, Ji-Hae; Kim, Ji-Hoon; Park, Mi-Kyoung; Park, Sehyeon; Park, Joon-Ho; Oh, Eun-Young; Lim, Tae-Sik; Cheong, Seongshim; Cho, In Hee; Choi, Jee Wook

2007-01-30

35

Reconstruction of complex oro-facial defects using the myocutaneous sub-mental artery flap.  

PubMed

Oro-facial defects require reconstruction that provides suitable colour match and texture. Moreover inner and outer cheek lining and bulk are key considerations. In cases of severe oro-facial infections concomitant mandibular abnormality, for example trismus, can mandate the need for tissue to obturate mandibular defects. We assessed the use of the myocutaneous sub-mental artery flap (MSA) in non-oncological patients with such defects. Twenty two consecutive patients were included in this case series. All patients were survivors of Cancrum Oris (NOMA). Demographic details, nutritional status and co-morbidities were recorded. Defects were classified according to the tissues destroyed; cheek, mandible, oral cavity, lip(s), nose and eye(s). Simultaneous procedures carried out were recorded. The surgical anatomy of the MSA is described. All patients had composite defects of the cheek and oral cavity plus another local anatomical structure. Adjunct procedures such as trismus release were carried out in 18/22 patients. Four patients required a return to theatre. There was no trismus recurrence observed. No flap losses were incurred. The MSA is a robust flap with minimal incidence of major complications. The MSA negates the need for microsurgical tissue transfer. Furthermore the MSA provides adequate bulk to obturate these defects. Future applications of the MSA may include complex oro-facial oncological defects. PMID:24209385

Saleh, D B; Fourie, L; Mizen, K D

2014-07-01

36

Guidelines and recommendations for assessment of somatosensory function in oro-facial pain conditions--a taskforce report.  

PubMed

The goals of an international taskforce on somatosensory testing established by the Special Interest Group of Oro-facial Pain (SIG-OFP) under the International Association for the Study of Pain (IASP) were to (i) review the literature concerning assessment of somatosensory function in the oro-facial region in terms of techniques and test performance, (ii) provide guidelines for comprehensive and screening examination procedures, and (iii) give recommendations for future development of somatosensory testing specifically in the oro-facial region. Numerous qualitative and quantitative psychophysical techniques have been proposed and used in the description of oro-facial somatosensory function. The selection of technique includes time considerations because the most reliable and accurate methods require multiple repetitions of stimuli. Multiple-stimulus modalities (mechanical, thermal, electrical, chemical) have been applied to study oro-facial somatosensory function. A battery of different test stimuli is needed to obtain comprehensive information about the functional integrity of the various types of afferent nerve fibres. Based on the available literature, the German Neuropathic Pain Network test battery appears suitable for the study of somatosensory function within the oro-facial area as it is based on a wide variety of both qualitative and quantitative assessments of all cutaneous somatosensory modalities. Furthermore, these protocols have been thoroughly described and tested on multiple sites including the facial skin and intra-oral mucosa. Standardisation of both comprehensive and screening examination techniques is likely to improve the diagnostic accuracy and facilitate the understanding of neural mechanisms and somatosensory changes in different oro-facial pain conditions and may help to guide management. PMID:21241350

Svensson, P; Baad-Hansen, L; Pigg, M; List, T; Eliav, E; Ettlin, D; Michelotti, A; Tsukiyama, Y; Matsuka, Y; Jääskeläinen, S K; Essick, G; Greenspan, J D; Drangsholt, M

2011-05-01

37

Oro-dental mucoadhesive proniosomal gel formulation loaded with lornoxicam for management of dental pain.  

PubMed

Abstract Oro-dental diseases are generally associated with pain that is controlled using oral tablets containing NSAIDs. Lornoxicam, a relatively new NSAID, is effective in relieving pain accompanying different oro-dental problems. The aim of the current research is to prepare oro-dental analgesic and anti-inflammatory gel using provesicular approach to deliver lornoxicam directly to the site of action in the oral cavity. Local administration of lornoxicam is expected to be superior to systemic delivery in pain relieving and poses less GIT adverse effects. Different surfactants were utilized to prepare the proniosomal gels that rapidly transform into nano-sized niosomes after hydration with the oral saliva. The effect of the surfactant structure on vesicles size distribution and entrapment efficiency percentage (EE%) was investigated. The proniosomal formulations were incorporated into carbopol hydrogels that were characterized regarding rheological and mucoadhesion properties. Moreover, ex-vivo mucosal membrane permeation studies were conducted for selected proniosomal gels to quantify the permeation parameters and assess the amount of drug deposited within the oral mucosa. Results revealed that mucoadhesive proniosomes formulation prepared using Span 60 was optimal as it was nano-sized and also showed the highest EE%. The transmucosal flux of lornoxicam, from these proniosomal formulations, across the oral mucosa was significantly higher (p?

Abdelbary, Ghada Ahmed; Aburahma, Mona Hassan

2014-07-24

38

Epidemic oro-facial Kaposi's sarcoma (eKS)--report on 124 cases.  

PubMed

Oro-facial epidemic Kaposi's sarcoma (eKS) was observed in 124 patients (123 homo-/bisexual men, average age 37.9 years, and one 35-year-old transsexual patient). Average survival time was 1 year 9 months (range: 3 months 4 years 6 months). 57.3% of the patients had died. The hard and/or soft palate, gingiva and tongue were most frequently affected, with falling frequency within these locations. Oral manifestations of eKS appear to be common; treatment modalities must be optimised. PMID:8298422

Reichart, P A; Langford-Kuntz, A; Pohle, H D

1993-07-01

39

Dentists' Preferences for Diagnosis, Management and Referral of Chronic Oro-Facial Pain: Results from a National Survey  

ERIC Educational Resources Information Center

Aim: To explore the diagnosis, treatment and referral patterns of chronic oro-facial pain patients by generalist primary care dentists (GDPs) in the UK. Methods: A cross-sectional survey was conducted using a non-stratified random sample of 500 GDPs who were selected from the General Dental Council register. A self-complete postal questionnaire…

Aggarwal, Vishal R.; Joughin, Amy; Zakrzewska, Joanna; Appelbe, Priscilla; Tickle, Martin

2012-01-01

40

HOW TO SEND FEDERAL AGENCY FUNDS TO THE DEPARTMENT OF ENERGY OAK RIDGE OFFICE (DOE-ORO)1  

E-print Network

HOW TO SEND FEDERAL AGENCY FUNDS TO THE DEPARTMENT OF ENERGY OAK RIDGE OFFICE (DOE-ORO)1 FISCAL appropriations--time and date subject to change. Overview Oak Ridge National Laboratory (ORNL) is a Department on cost, schedule, and customer satisfaction. ORNL will forward for Department of Energy Oak Ridge Office

41

Lower Cretaceous corals and stratigraphy of the Bisbee Group (Cerro de Oro and Lampazos areas), Sonora, Mexico  

Microsoft Academic Search

Stratigraphic sections of the Bisbee Group in northwestern Mexico have been studied. Several lithostratigraphic units from the Cerro de Oro and Lampazos areas, characterized by mainly carbonate\\/clastic shallow water sequences, are discussed in this paper. In the Lampazos area these sediments are grouped into the Agua Salada, Lampazos, Espinazo del Diablo, and Nogal Formations. In the Lower Cretaceous sections of

R. C. Baron-Szabo; C. M. González-León

1999-01-01

42

Effects of MPH-OROS on the Organizational, Time Management, and Planning Behaviors of Children with ADHD  

ERIC Educational Resources Information Center

A double-blind, placebo-controlled, crossover design study was done to evaluate the effects of methylphenidate-osmotic-release oral systems (MPH-OROS) on the organization, time management, and planning (OTMP) of children with attention deficit hyperactivity disorder (ADHD). Results show significant improvements on the OTMP of children with ADHD in…

Abikoff, Howard; Nissley-Tsiopinis, Jenelle; Gallagher, Richard; Zambenedetti, Maurizio; Seyffert, Michael; Boorady, Roy; McCarthy, John

2009-01-01

43

A Randomized, Single-Blind, Substitution Study of OROS Methylphenidate (Concerta) in ADHD Adults Receiving Immediate Release Methylphenidate  

ERIC Educational Resources Information Center

Objective: The main aim of this study was to examine the efficacy, tolerability, and compliance of an extended-release formulation of methylphenidate (OROS-MPH) in adults with ADHD receiving immediate-release methylphenidate (IR-MPH). Method: Participants were outpatient adults with ADHD who were stable on IR-MPH-administered TID. Participants…

Spencer, Thomas J.; Mick, Eric; Surman, Craig B. H.; Hammerness, Paul; Doyle, Robert; Aleardi, Megan; Kotarski, Meghan; Williams, Courtney G.; Biederman, Joseph

2011-01-01

44

Assessment of the environmental changes in Oro Lake, Mali, using MSS images  

NASA Astrophysics Data System (ADS)

Environmental changes around the Oro Lake (Mali) which, with other lakes (Fati, Faguibine, Tele), represents an important hydrological resource of the Inland Delta of the Niger river, have been assessed by means of Landsat MSS imagery analysis. After data calibration and atmospheric correction, different color composites, band ratios and image differences were selected. Subsequently, the spectral features of the principal morphological units were analyzed using the satellite data, and were compared with the morphological characteristics detected and mapped in 1957 by Tricart from field work and aerial photographs. The morphological changes highlighted by satellite data therefore represent an interesting update of the old map in a region in which it is very difficult and expensive to perform ground surveys.

Alessandro, Valeria; Carla, Roberto

1996-12-01

45

[Thermo- and scintigraphy with 67Ga citrate in the diagnosis of oro- and parapharyngeal tumors].  

PubMed

The authors analyzed the results of thermographic and scintigraphic (using 67Ga-citrate produced in the USSR) investigations in 41 patients: 10 with tumors of the oral cavity, 12 with oropharyngeal tumors, and 19 with parapharyngeal tumors. Of the latter 10 had morphologically verified benign tumors, 5--mixed type tumors, and 4--malignant tumors (sarcoma in 2 patients, a thyroid cancer metastasis to the parapharyngeal lymph nodes in 1, malignant chemodectoma in 1). Thermography and scintigraphy positive results (the absence of hyperthermia and RP hyperfixation in a tumor) were obtained in 7 of 10 patients with benign parapharyngeal tumors. Thermography false-positive results were obtained in 3 patients, however 67Ga-citrate accumulation was undetectable in these patients' tumors making the diagnosis more accurate. Thermography and scintigraphy results were positive in all 22 patients with malignant oropharyngeal (the oral cavity and oropharynx) tumors. Thermography and scintigraphy positive results were also noted in all 5 patients with parapharyngeal mixed tumors which could be associated with raised tumor tissue biological activity. The data obtained suggested a possibility of the use of thermography and scintigraphy in the diagnosis of oro-and parapharyngeal tumors. PMID:3294558

Gabunov, R I; Kurbandurdyev, A G; Lenskaia, O P; Bogdasarov, Iu V

1988-07-01

46

Definitive Radiotherapy versus Postoperative Radiotherapy of Patients with Oro- and Hypopharyngeal Cancer: Impact of Prognostic Factors  

PubMed Central

Purpose. To compare the impact of prognostic factors of patients treated with definitive radio(chemo)therapy versus patients treated with surgery and postoperative radiotherapy for squamous cell carcinoma of the oro- and hypopharynx. Patients and Methods. 162 patients treated with definitive radiotherapy and 126 patients treated with postoperative radiotherapy were retrospectively analysed. The impact of the prognostic factors gender, age, total tumor volume (TTV), pre-radiotherapy hemoglobin level (Hb-level), tumor site, T- and N-classification, radiotherapy interruptions >5 days, radiotherapy versus simultaneous radiochemotherapy, R-status and time interval between surgery and radiotherapy were investigated. Results. The median follow-up time for the censored patients treated with definitive radio(chemo)therapy was 28.5 months and for postoperative radiotherapy 36.5 months. On univariate analysis, the TTV, Hb-level, and simultaneous radiochemotherapy had a significant impact on the survival of patients treated with definitive radio(chemo)therapy. For patients treated with postoperative radiotherapy, only the TTV showed a statistical trend for the survival (P = 0.13). On multivariate analysis, the TTV and simultaneous radiochemotherapy maintained their statistical significance for patients treated with definitive raditherapy, and the TTV, the statistical trend for patients treated with postoperative radiotherapy (P = 0.19). Conclusions. The TTV was the predominant prognostic factor for both, patients treated with definitive or postoperative radiotherapy. PMID:22315594

Rudat, Volker; Ahmet-Osman, Salia; Schramm, Oliver; Dietz, Andreas

2012-01-01

47

A fault-tolerant modular control approach to multi-robot perimeter patrol Alessandro Marino, Lynne E. Parker, Gianluca Antonelli, Fabrizio Caccavale and Stefano Chiaverini  

E-print Network

methodologies are based on the assumption of static environments. When dealing with swarms of autonomous robotsA fault-tolerant modular control approach to multi-robot perimeter patrol Alessandro Marino, Lynne scale multi-robot systems is motivated by a number of desirable features, such as scalability, fault

Parker, Lynne E.

48

First-principles characterization of Ni diffusion kinetics in -NiAl Kristen A. Marino1 and Emily A. Carter2  

E-print Network

First-principles characterization of Ni diffusion kinetics in -NiAl Kristen A. Marino1 and Emily A calculations are performed to examine five postulated diffusion mechanisms for Ni in NiAl: next that the triple defect mechanism and 110 six-jump cycle both are likely contributors to Ni diffusion in NiAl since

Carter, Emily A.

49

Formulation, development, and performance evaluation of metoclopramide HCl oro-dispersible sustained release tablet.  

PubMed

The present study was undertaken to develop and evaluate an oro-dispersible, sustained release tablet of metoclopramide HCl. The technology was comprised of developing sustained release microparticles, and compression of resultant microspheres into a fast dispersible tablet by direct compression. The microspheres of metoclopramide HCl were prepared by an emulsification-solvent evaporation method using ethylcellulose as the matrix polymer. The prepared microspheres were evaluated for morphology, particle size, entrapment efficiency, and in vitro drug release characteristics. Scanning electron microscopy demonstrated spherical particles with a mean diameter of 81.27 ± 5.87 ?m and the drug encapsulation efficiency was found to be 70.15 ± 3.06%. The process and formulation variables such as rotation speed, polymer concentration, and drug concentration influenced the drug encapsulation efficiency and in vitro drug release. Optimized microspheres were compressed into tablets which were comprised of metoclopramide HCl microspheres, 53% (w/v) of D-mannitol granules, 7% (w/w) of Polyplasdone XL 10, and 0.5% (w/w) of calcium stearate. The tablets demonstrated a hardness of 59 ± 3 N, friability of 0.21% and disintegration time of 27 ± 3 sec. The formulations were subjected to stability studies as per ICH guidelines and were found to be stable after a 6 month study. In vivo experiments conducted in rats demonstrated that a constant level of metoclopramide HCl in plasma could be maintained for up to 20 h at a suitable concentration for antiemetic activity. An appropriate combination of excipients made it possible to obtain orally disintegrating sustained release tablets of metoclopramide HCl using simple and conventional techniques. PMID:22076769

Kasliwal, Nikhil; Negi, Jeetendra Singh; Jugran, Vandana; Jain, Rahul

2011-10-01

50

A Multicenter, Open-Label Trial to Evaluate the Quality of Life in Adults with ADHD Treated with Long-Acting Methylphenidate (OROS MPH): Concerta Quality of Life (CONQoL) Study  

ERIC Educational Resources Information Center

The available literature provides few studies on the effectiveness of methylphenidate in improving quality of life in individuals with ADHD. Objective: To assess the effectiveness of Methyphenidate OROS formulation (OROS MPH) through QoL in adults with ADHD. Method: A 12-week, multicenter, open-label trial involving 60 patients was used. The…

Mattos, Paulo; Rodrigues Louza, Mario; Fernandes Palmini, Andre Luis; de Oliveira, Irismar Reis; Lopes Rocha, Fabio

2013-01-01

51

Assessment of oral side effects of Antiepileptic drugs and traumatic oro-facial injuries encountered in Epileptic children  

PubMed Central

Background: Epilepsy is a chronic disorder with unpredictably recurring seizure. Uncontrolled attacks can put patients at risk of suffering oro-facial trauma. Antiepileptic drugs (AED) provide satisfactory control of seizures in most of the patients with epilepsy. However use of AED has been found to cause many side effects inclusive of side effects in the oral cavity also. Materials & Methods: This study was conducted on 150 epileptic children, who were on anti epileptic medication for one year. Results: Gingival over growth was seen as common side effect of the AED drugs. Lip and cheek biting were the most common soft tissue injury, while tooth fracture was the most common hard tissue dental injury. Conclusion: General physicians, physicians & dentists should be well aware of the potential side effects of AED. A Dentist should be well versed and trained to manage oro-facial injuries in the emergency department. How to cite the article: Ghafoor PA, Rafeeq M, Dubey A. Assessment of oral side effects of Antiepileptic drugs and traumaticoro-facial injuries encountered in Epileptic children. J Int Oral Health 2014;6(2):126-8. PMID:24876713

Ghafoor, P A Fazal; Rafeeq, Mohammed; Dubey, Alok

2014-01-01

52

Interacting with the User in Calendar Management Liliana Ardissono, Giovanna Petrone, Marino Segnan, and Gianluca Torta  

E-print Network

problems by incrementally exploring the solution space. Keywords: mixed-initiative scheduling, temporal scheduling options while being aware, at each stage, of their pros and cons. Thus, (s)he can follow to the adoption of a mixed-initiative interaction model, the user can incremen- tally explore the available

Ardissono, Liliana

53

Contrast of Hemispheric Lateralization for Oro-Facial Movements between Learned Attention-Getting Sounds and Species-Typical Vocalizations in Chimpanzees: Extension in a Second Colony  

ERIC Educational Resources Information Center

Studies involving oro-facial asymmetries in nonhuman primates have largely demonstrated a right hemispheric dominance for communicative signals and conveyance of emotional information. A recent study on chimpanzee reported the first evidence of significant left-hemispheric dominance when using attention-getting sounds and rightward bias for…

Wallez, Catherine; Schaeffer, Jennifer; Meguerditchian, Adrien; Vauclair, Jacques; Schapiro, Steven J.; Hopkins, William D.

2012-01-01

54

An Analysis of Patient Adherence to Treatment during a 1-Year, Open-Label Study of OROS[R] Methylphenidate in Children with ADHD  

ERIC Educational Resources Information Center

Objective: Treatment adherence is an important aspect of ADHD symptom management, but there are many factors that may influence adherence. Method: This analysis assessed adherence to OROS methylphenidate during a 1-year, open-label study in children. Adherence was defined as the number of days medication was taken divided by the number of days in…

Faraone, Stephen V.; Biederman, Joseph; Zimmerman, Brenda

2007-01-01

55

Blocking opioid receptors alters short-term feed intake and oro-sensorial preferences in weaned calves.  

PubMed

Opioid peptides may participate in the control of feed intake through mechanisms involving pleasure reward linked to consumption of palatable feed. The objective of this study was to determine whether blocking opioid receptors might void oro-sensorial preferences of calves, and affect circulating glucose, insulin, and anorexigenic hormones in fasted and fed calves. Two experiments involved 32 Holstein calves [body weight (BW)=86.5±1.73 kg, age=72±0.6 d]. In experiment 1, all calves received an ad libitum choice of the same feed either unflavored or flavored with a sweetener (Luctarom SFS-R, Lucta, Montornès del Vallès, Spain). Feed consumption was recorded every 2 h from 0800 to 1400 h for 3 consecutive days to verify the establishment of an oro-sensorial preference for sweet feed (SF). The SF was preferred over the control feed (CF) at all recorded times. In experiment 2, calves were subjected to a 2 × 2 factorial design to study the interaction between opioid activity and metabolic state. Half of the calves were fasted for 14 h (FAS), whereas the other half remained well fed (FED). Within each of these groups, at feeding time (0800 h), half of the calves received an i.v. injection of naloxone (NAL, an opioid receptor antagonist; 1 mg/kg of BW) and the other half was injected with saline solution (SAL; 0.9% NaCl). Therefore, treatments were FED-NAL, FED-SAL, FAS-NAL, and FAS-SAL. Blood samples were taken at -10, 20, 180, and 240 min relative to NAL or SAL injections. As expected, cumulative consumption of starter feed was greater in FAS than in FED calves. Total feed consumption 2 h after feeding was lower in NAL than in SAL calves. Calves in the FAS group did not discern between CF and SF during the first 4 h after feed offer. Preference for SF was greater in SAL than in NAL calves. Calves in the FED-SAL treatment preferred SF at 2 and 6 h after feed offer and tended to prefer SF at 4 h after feeding. However, FED-NAL calves did not discern between SF and CF during the first 4 h after feeding and tended to prefer SF only after 6 h from feeding. Plasma glucose, insulin, and cholecystokinin concentrations were greater in FED than in FAS calves. Injection of naloxone decreased plasma glucagon-like peptide-1 (GLP-1) in NAL calves. Blocking opioid receptors reduced intake the first 2 h after naloxone injection in FED calves, altered oro-sensorial preferences, and reduced plasma GLP-1 concentration. In conclusion, the opioid peptide system may control short-term feed intake by modulating the oro-sensorial response triggered by feed consumption, especially when calves are fed ad libitum. PMID:22541480

Montoro, C; Ipharraguerre, I R; Bach, A

2012-05-01

56

An open-label, 1-year extension study of the long-term safety and efficacy of once-daily OROS® hydromorphone in patients with chronic cancer pain  

Microsoft Academic Search

BACKGROUND: Opioid analgesics have proven efficacy in the short-term management of chronic cancer pain, but data on their long-term use is more limited. OROS® hydromorphone is a controlled-release formulation of oral hydromorphone that may be particularly well suited to long-term management of chronic cancer pain because it provides stable plasma concentrations and consistent analgesia with convenient once-daily dosing. The objective

Magdi Hanna; Alberto Tuca; John Thipphawong

2009-01-01

57

trkA modulation of developing somatosensory neurons in oro-facial tissues: tooth pulp fibers are absent in trkA knockout mice  

Microsoft Academic Search

To investigate the nerve growth factor requirement of developing oro-facial somatosensory afferents, we have studied the survival of sensory fibers subserving nociception, mechanoreception or proprioception in receptor tyrosine kinase (trkA) knockout mice using immunohistochemistry. trkA receptor null mutant mice lack nerve fibers in tooth pulp, including sympathetic fibers, and showed only sparse innervation of the periodontal ligament. Ruffini endings were

S. MATSUO; H. ICHIKAWA; T. A. HENDERSON; I. SILOS-SANTIAGO; M. BARBACID; J. J. A. ARENDSa; M. F. JACQUINa

2001-01-01

58

Movement of water through the thick unsaturated zone underlying Oro Grande and Sheep Creek Washes in the western Mojave Desert, USA  

USGS Publications Warehouse

Previous studies indicate that a small quantity of recharge occurs from infiltration of streamflow in intermittent streams in the upper Mojave River basin, in the western Mojave Desert, near Victorville, California. Chloride, tritium, and stable isotope data collected in the unsaturated zone between 1994 and 1998 from boreholes drilled in Oro Grande and Sheep Creek Washes indicate that infiltration of streamflow occurs to depths below the root zone, and presumably to the water table, along much of Oro Grande Wash and near the mountain front along Sheep Creek Wash. Differences in infiltration at sites along each wash are the result of hydrologic variables such as proximity to the mountain front, quantity of streamflow, and texture of the subsurface deposits. Differences in infiltration between the washes are the result of large-scale geomorphic processes. For example, Oro Grande wash is incised into the Victorville fan and infiltration has occurred at approximately the same location over recent geologic time. In contrast, Sheep Creek Wash overlies an active alluvial fan and the stream channel can move across the fan surface through time. Infiltration does not occur to depths below the root zone at control sites outside of the washes.

Izbicki, J.A.; Radyk, J.; Michel, R.L.

2002-01-01

59

Waste generation forecast for DOE-ORO`s Environmental Restoration OR-1 Project: FY 1995-FY 2002, September 1994 revision  

SciTech Connect

A comprehensive waste-forecasting task was initiated in FY 1991 to provide a consistent, documented estimate of the volumes of waste expected to be generated as a result of U.S. Department of Energy-Oak Ridge Operations (DOE-ORO) Environmental Restoration (ER) OR-1 Project activities. Continual changes in the scope and schedules for remedial action (RA) and decontamination and decommissioning (D&D) activities have required that an integrated data base system be developed that can be easily revised to keep pace with changes and provide appropriate tabular and graphical output. The output can then be analyzed and used to drive planning assumptions for treatment, storage, and disposal (TSD) facilities. The results of this forecasting effort and a description of the data base developed to support it are provided herein. The initial waste-generation forecast results were compiled in November 1991. Since the initial forecast report, the forecast data have been revised annually. This report reflects revisions as of September 1994.

Not Available

1994-12-01

60

Tactile sensory and pain thresholds in the face and tongue of subjects asymptomatic for oro-facial pain and headache.  

PubMed

The aim of this study was to examine the tactile sensory and pain thresholds in the face, tongue, hand and finger of subjects asymptomatic for pain. Sixteen healthy volunteers (eight men and eight women, mean age 35·7 years, range 27-41) participated. Using Semmes-Weinstein monofilaments, the tactile detection threshold (TDT) and the filament-prick pain detection threshold (FPT) were measured at five sites: on the cheek skin (CS), tongue tip (TT), palm side of the thenar skin (TS), dorsum of the hand (DH) and the finger tip (FT). The difference between the tactile sensory and pain threshold (FPT-TDT) was also calculated. Both for the TDT and FPT, TT and DH had the lowest and highest values, respectively. As for the FPT-TDT, there were no significant differences among the measurement sites. As the difference between FPT and TDT (FPT-TDT) is known to be an important consideration in interpreting QST (quantitative sensory testing) data and can be altered by neuropathology, taking the FPT-TDT as a new parameter in addition to the TDT and FPT separately would be useful for case-control studies on oro-facial pain patients with trigeminal neuralgia, atypical facial pain/atypical odontalgia and burning mouth syndrome/glossodynia. PMID:25041286

Okayasu, I; Komiyama, O; Ayuse, T; De Laat, A

2014-12-01

61

Processing capabilties for the elimination of contaminated metal scrapyards at DOE/ORO-managed sites. [Metal smelting facility  

SciTech Connect

Capabilities exist for reducing all the contaminated nickel, aluminum, and copper scrap to ingot form by smelting. Processing these metals at existing facilities could be completed in about 5 or 6 years. However, these metals represent only about 20% of the total metal inventories currently on hand at the DOE/ORO-managed sites. No provisions have been made for the ferrous scrap. Most of the ferrous scrap is unclassified and does not require secured storage. Also, the potential resale value of the ferrous scrap at about $100 per ton is very low in comparison. Consequently, this scrap has been allowed to accumulate. With several modifications and equipment additions, the induction melter at PGDP could begin processing ferrous scrap after its commitment to nickel and aluminum. The PGDP smelter is a retrofit installation, and annual throughput capabilities are limited. Processing of the existing ferrous scrap inventories would not be completed until the FY 1995-2000 time frame. An alternative proposal has been the installation of induction melters at the other two enrichment facilities. Conceptual design of a generic metal smelting facility is under way. The design study includes capital and operating costs for scrap preparation through ingot storage at an annual throughput of 10,000 tons per year. Facility design includes an induction melter with the capability of melting both ferrous and nonferrous metals. After three years of operation with scrapyard feed, the smelter would have excess capacity to support on-site decontamination and decomissioning projects or upgrading programs. The metal smelting facility has been proposed for FY 1984 line item funding with start-up operations in FY 1986.

Mack, J.E.; Williams, L.C.

1982-01-01

62

Tolerability and effects of OROS® MPH (Concerta ®) on functioning, severity of disease and quality of life in children and adolescents with ADHD: results from a prospective, non-interventional trial.  

PubMed

Attention-deficit/hyperactivity disorder may have substantial impact on family life, peer interactions, and quality of life. Stimulants are recommended as first-line pharmacotherapy for ADHD. OROS(®) MPH (Concerta(®)) is a long-acting preparation with duration of effect for up to 12 h. In this 8-week, prospective, open-label, non-interventional trial the impact of therapy with OROS(®) MPH on functioning in four different areas of life (school, recreation, family life, and peer interaction), severity of disease, and quality of life (QoL) as well as tolerability were investigated under daily routine care. 306 patients, aged 10.2±2.3 years, were either transitioned to OROS(®) MPH from short-acting, immediate-release MPH (-IR) preparations (n=231; 75%), or treatment was initiated with OROS(®) MPH in MPH-naïve patients (n =75; 25%). In both groups, therapy with OROS(®) MPH was associated with significant improvements in daily functioning, severity of disease, and QoL. Adverse events (AE) were documented in 160 patients (52.3%). In 95 patients (31.0%) a causal relationship was assessed as at least possible. Four serious AEs were reported in 2 patients and rated as doubtfully related to study medication. Most frequent AEs (?5% of patients) were insomnia, anorexia, ineffectiveness of medication, and headache. In 12.1% of patients AE led to discontinuation of study participation. Considering the limitations of this non-interventional study, the results refer to the importance of a therapy that covers not only school-time, but also takes other areas of life into account. Initiating treatment with long-acting preparations, such as OROS(®) MPH in MPH-naïve patients might be a feasible option. PMID:21432582

Gerwe, Martin; Stollhoff, Kirsten; Mossakowski, Jacek; Kuehle, Hans-Juergen; Goertz, Ulrich; Schaefer, Christopher; Bogdanow, Manuela; Heger, Steffen

2009-12-01

63

Predictors and impact of non-adherence in adults with attention-deficit/hyperactivity disorder receiving OROS methylphenidate: results from a randomized, placebo-controlled trial  

PubMed Central

Background Medication non-adherence has an important impact on treatment efficacy and healthcare burden across a range of conditions and therapeutic areas. The aim of this analysis was to determine predictors of non-adherence and impact of non-adherence on treatment response in adults with attention-deficit/hyperactivity disorder (ADHD). Methods Post-hoc analysis of a 13-week randomized, double-blind placebo-controlled study of OROS methylphenidate (MPH) 54 and 72 mg/day. Primary efficacy variable was the Conners’ Adult ADHD Rating Scale – Screening Version (CAARS:O-SV). Daily adherence was calculated as average daily adherence (100 × capsules taken/2), with overall adherence calculated as the average daily adherence. Predictors of adherence were assessed using mixed-effects logistic regression. Descriptive statistics were generated for change in CAARS:O-SV score for adherent (> 95% adherence) and non-adherent subjects. Predictors of change were analyzed using a mixed model. Results Subjects were allocated to OROS MPH (54 mg, n = 87; 72 mg, n = 92) or placebo (n = 97). Mean adherence was 92.6% and 93.3% (OROS MPH 54 and 72 mg/day, respectively), versus 97.5% (placebo). Adherence was higher and less variable in completers. Factors significantly associated with non-adherence included female sex, shorter time since ADHD diagnosis, higher education level (completion of university) and score on the Drug Use Screening Inventory psychiatric disorders subscale. Improvements from baseline in CAARS:O-SV score were numerically greater in subjects defined as adherent than in those who were non-adherent. Significant predictors of CAARS:O-SV change in patients who completed the study included percentage adherence up to the point of assessment (p < 0.0001), baseline score (p < 0.0001) and family history of ADHD (p = 0.0003). Conclusion The results of this analysis suggest that newly diagnosed patients, those with a high score on the DUSI-R psychiatric disorder scale, women, and subjects with high educational degrees may be at increased risk of non-adherence. Clinicians and policymakers should therefore pay special attention to these individuals, as non-adherence is a significant predictor of reduced response to treatment. Trial registration EudraCT #: 2007-002111-82 PMID:23347693

2013-01-01

64

A New Zebrafish Model of Oro-Intestinal Pathogen Colonization Reveals a Key Role for Adhesion in Protection by Probiotic Bacteria  

PubMed Central

The beneficial contribution of commensal bacteria to host health and homeostasis led to the concept that exogenous non-pathogenic bacteria called probiotics could be used to limit disease caused by pathogens. However, despite recent progress using gnotobiotic mammal and invertebrate models, mechanisms underlying protection afforded by commensal and probiotic bacteria against pathogens remain poorly understood. Here we developed a zebrafish model of controlled co-infection in which germ-free zebrafish raised on axenic living protozoa enabled the study of interactions between host and commensal and pathogenic bacteria. We screened enteric fish pathogens and identified Edwardsiella ictaluri as a virulent strain inducing a strong inflammatory response and rapid mortality in zebrafish larvae infected by the natural oro-intestinal route. Using mortality induced by infection as a phenotypic read-out, we pre-colonized zebrafish larvae with 37 potential probiotic bacterial strains and screened for survival upon E. ictaluri infection. We identified 3 robustly protective strains, including Vibrio parahaemolyticus and 2 Escherichia coli strains. We showed that the observed protective effect of E. coli was not correlated with a reduced host inflammatory response, nor with the release of biocidal molecules by protective bacteria, but rather with the presence of specific adhesion factors such as F pili that promote the emergence of probiotic bacteria in zebrafish larvae. Our study therefore provides new insights into the molecular events underlying the probiotic effect and constitutes a potentially high-throughput in vivo approach to the study of the molecular basis of pathogen exclusion in a relevant model of vertebrate oro-intestinal infection. PMID:22911651

Bégaud, Evelyne; Herbomel, Philippe; Levraud, Jean-Pierre; Ghigo, Jean-Marc

2012-01-01

65

The restart of meteorological observations in the 19th century in Lisbon: the contribution of Marino Miguel FRANZINI (1779-1861)  

NASA Astrophysics Data System (ADS)

After the early meteorological observations of the 1770s to the 1790s in continental Portugal (including a 5 year daily series by J. Velho), there were hardly any until 1815. In December 1815, a meteorological station was set up in Lisbon by Marino Miguel Franzini (1779-1861), an engineer who was also actively involved in Politics (liberal party). Following the tradition of the 18th century enlightenment movement, he took a keen interest in Nature and Sciences, particularly in the "influence" of weather and climate on health and agriculture. Franzini started his observations by request of a physician who sought to understand the reasons why the maximum mortality occurred on the summer months, unlike in northern countries of Europe where maximum mortality occurred in winter (as it happens nowadays in Portugal). The deterministic background of the two scientists is clear. Franzini was a member of the Lisbon Academy of Sciences (founded in 1799) and had contact with foreign Academies and foreign scientists. His instruments were carefully constructed and described, including graduation scales, and stations' location was indicated. Data from two years observations (several meteorological variables) was published in the Academy of Sciences Memoirs. From 1818 until 1826 and from 1835 until 1856 data was divulged in journals and newspapers, such as the "Journal of Medical Sciences", together with data on necrology in some of Lisbon parishes (illustrating the interest of physicians on weather); meteorological data and information about agriculture was also published in the "Lisbon Gazette". Unfortunately, there are hardly any daily data, as Franzini grouped his records according to weather types, as will be explained. Franzini's series will be presented in our talk. The gap between 1826 and 1835 was due to the political activities in which Franzini was involved: the civil war (liberals against absolutist) disruptedscientific research in Portugal. Official meteorological observations began in Lisbon,in December 1854, in a site not far away from Franzini's station. The long series of Lisbon includes the 1835-54 Franzini's series.

Alcoforado, Maria-Joao; Nunes, Fatima

2013-04-01

66

A new point-of-care portable immunosensor for non-invasive assessment of oro-ileal transit time by oral fluid tauroursodeoxycholate measurement after its oral load.  

PubMed

A non-invasive test for oro-ileal transit time (OITT) evaluation was developed, based on the measurement of tauroursodeoxycholic acid (TUDCA) oral fluid concentration profile after its oral administration. Exploiting the fact that TUDCA is actively absorbed only in the ileum, OITT is measured as the time corresponding to TUDCA maximum oral fluid concentration (tmax). To measure oral fluid TUDCA concentration in a point-of-care setting, an ultrasensitive portable immunosensor was developed, based on a competitive chemiluminescent enzyme immunoassay (CL-EIA), using immobilized anti-TUDCA antibody and an ursodeoxycholic acid (UDCA)-peroxidase conjugate as tracer, detected by enhanced chemiluminescence employing a portable charge-coupled device (CCD)-based device. The test was validated in 24 healthy subjects before and after treatment with Loperamide, a drug that increases OITT. The developed CL-EIA was accurate and precise, with a LLOQ of 50 pmol L(-1). The measured OITT for healthy subjects (291 ± 50 min) was fairly well correlated with OITT values obtained by measuring TUDCA in serum (r=0.89). An increased OITT was observed in all the studied subjects after Loperamide treatment. The CL immunosensor can be employed directly in gastroenterology and paediatric units and it can thus represent a new non-invasive simple test for OITT evaluation in a point-of-care setting, with improved diagnostic utility. PMID:23587552

Simoni, Patrizia; Magliulo, Maria; Mirasoli, Mara; Vestito, Amanda; Festi, Davide; Roda, Giulia; Colecchia, Antonio; Roda, Aldo

2013-01-01

67

Oro-gustatory perception of dietary lipids and calcium signaling in taste bud cells are altered in nutritionally obesity-prone Psammomys obesus.  

PubMed

Since the increasing prevalence of obesity is one of the major health problems of the modern era, understanding the mechanisms of oro-gustatory detection of dietary fat is critical for the prevention and treatment of obesity. We have conducted the present study on Psammomys obesus, the rodent desert gerbil which is a unique polygenic natural animal model of obesity. Our results show that obese animals exhibit a strong preference for lipid solutions in a two-bottle test. Interestingly, the expression of CD36, a lipido-receptor, in taste buds cells (TBC), isolated from circumvallate papillae, was decreased at mRNA level, but remained unaltered at protein level, in obese animals. We further studied the effects of linoleic acid (LA), a long-chain fatty acid, on the increases in free intracellular calcium (Ca(2+)) concentrations, [Ca(2+)]i, in the TBC of P. obesus. LA induced increases in [Ca(2+)]i, largely via CD36, from intracellular pool, followed by the opening of store-operated Ca(2+) (SOC) channels in the TBC of these animals. The action of this fatty acid on the increases in [Ca(2+)]i was higher in obese animals than that in controls. However, the release of Ca(2+) from intracellular stores, studied also by employing thapsigargin, was lower in TBC of obese animals than control rodents. In this study, we show, for the first time, that increased lipid intake and altered Ca(2+) signaling in TBC are associated with obesity in Psammomys obesus. PMID:23936306

Abdoul-Azize, Souleymane; Atek-Mebarki, Feriel; Bitam, Arezki; Sadou, Hassimi; Koceïr, Elhadj Ahmed; Khan, Naim Akhtar

2013-01-01

68

Oro-Gustatory Perception of Dietary Lipids and Calcium Signaling in Taste Bud Cells Are Altered in Nutritionally Obesity-Prone Psammomys obesus  

PubMed Central

Since the increasing prevalence of obesity is one of the major health problems of the modern era, understanding the mechanisms of oro-gustatory detection of dietary fat is critical for the prevention and treatment of obesity. We have conducted the present study on Psammomys obesus, the rodent desert gerbil which is a unique polygenic natural animal model of obesity. Our results show that obese animals exhibit a strong preference for lipid solutions in a two-bottle test. Interestingly, the expression of CD36, a lipido-receptor, in taste buds cells (TBC), isolated from circumvallate papillae, was decreased at mRNA level, but remained unaltered at protein level, in obese animals. We further studied the effects of linoleic acid (LA), a long-chain fatty acid, on the increases in free intracellular calcium (Ca2+) concentrations, [Ca2+]i, in the TBC of P. obesus. LA induced increases in [Ca2+]i, largely via CD36, from intracellular pool, followed by the opening of store-operated Ca2+ (SOC) channels in the TBC of these animals. The action of this fatty acid on the increases in [Ca2+]i was higher in obese animals than that in controls. However, the release of Ca2+ from intracellular stores, studied also by employing thapsigargin, was lower in TBC of obese animals than control rodents. In this study, we show, for the first time, that increased lipid intake and altered Ca2+ signaling in TBC are associated with obesity in Psammomys obesus. PMID:23936306

Bitam, Arezki; Sadou, Hassimi; Koceïr, Elhadj Ahmed; Khan, Naim Akhtar

2013-01-01

69

Conversación con Ricardo Monti  

E-print Network

las carreras sucedía lo siguiente: yo quería ser e iba a ser escritor. Empecé filosofía y cursé seis o siete materias. Luego inicié la carrera de psi cología, pero mis estudios de psicología se interrumpieron cuando estrené mi primera obra de teatro... caos, organizar una serie de sensaciones e ideas, que impliquen cierta forma, cierta organización. Además, cada obra mía se empalma con la otra, como si yo buscara obscuramente no solamente organizar ese caos en cada obra, sino ir organizándolo con...

Driskell, Charles B.

1979-04-01

70

Climatic variability and human impact in Mesoamerica during the last 3,000 yr: the case of Lake Santa Maria Del Oro, Western Mexico  

NASA Astrophysics Data System (ADS)

During the last decades a number of lacustrine records from Mesoamerica have documented climatic changes and episodes of intense human impact. These records are concentrated in the Maya region and the in high altitude basins of central and eastern Mexico, few studies have been undertaken in western Mexico. We believe that a regional perspective of the recorded changes can provide a better understanding of the climatic trends and mechanisms controlling these changes as well as of the regional extent, intensity and timing of the episodes of human impact. For this reason we started a multidisciplinary project to study the lake sediments from Santa Maria del Oro (SMO), a crater lake in western-central Mexico (750 m asl). SMO is located in a region with tropical sub-humid climate(annual pp 1,250 mm/yr, mean annual temperature 21°C), with a short summer rainy season mainly related with the onset of the North American Monsoon (NAM) and the entrance of Pacific tropical storms and/or hurricanes. This site is therefore site sensitive to variations in the intensity of the NAM circulation. Two master sequences are available from this lake. A ca. 9 m long core (ca. 2,500 yr BP, with 8 AMS 14-C dates) was recovered using a Usinger piston corer from a relatively shallow area of the lake (12 m). These sediments are laminated, mostly with alternation of brown silt and sand layers. It has been studied for: magnetic mineralogy, ostracodes, geochemistry, TIC and TOC. We are now including diatom and pollen data to improve previous paleolimnological interpretations. The second sequence, also ca. 9 m long (ca. 4,500 yr BP, with 6 14-C AMS dates), was recovered using the Limnological Research Center (LRC at the U. of Minnesota) Kullemberg gravity corer (MOLE Mexico-USA-UK collaborative project). This sequence is also laminated, mostly between brown and black silts with finely laminated carbonate layers. High resolution ITRAX XRD elemental analysis data are available for this core. The main changes recorded in the SMO are: a concentrated lake phase between ca. AD 600 to 1000 (end of Classic) which suggests drier climates. A period of more diluted lake waters is identified from AD 1000 to 1260 (Postclassic) which is marked by higher sedimentation rates and the presence of Zea pollen. The year AD 1000 is identified as a turning point in climatic conditions in most of Mesoamerica.

Caballero, Margarita; Sosa, Susana; Rodríguez, Alejandro; Lozano, Socorro; Vázquez, Gabriel; Ortega, Beatriz; Vilaclara, Gloria

2010-05-01

71

Entrevista con Enrique Buenaventura  

E-print Network

, era muy terrible ya, realmente muy feroz, esta escalada somocista. En tonces, la respuesta también fue tan firme que empezó a desmoralizar a la Guardia. Te contaré un caso. En Masalla, en el mercado, las vendedoras nos contaron cómo se había... refugiado allí la Guardia, muy bien armada, con mucho parque y resultaba muy difícil sacarla de allí. Entonces las mismas mujeres del mercado, que había sido anteriormente bombardeado, salieron en grupo y fueron a tocar a la puerta donde estaba metida la...

Dí ez, Luys A.

1981-04-01

72

Reasoning about Time Constraints in a Mixed-Initiative Calendar Manager Liliana Ardissono and Giovanna Petrone and Marino Segnan and Gianluca Torta  

E-print Network

of their properties, needed to present the pros and cons of each possible solution to the user. Keywords: mixed a mixed-initiative scheduling model supporting the user's awareness dur- ing the exploration of the solution space. The paper de- scribes the temporal reasoning techniques underlying MARA (Mixed

Ardissono, Liliana

73

Entrevista con José Triana  

E-print Network

cenagoso. ¿Tú has visto a esos equilibristas que atraviesan de un lado a otro en un circo, en una cuerda floja? Y tú los ves que van pasando. . . . Pues eso yo creo que es una de las definiciones que podría plantearme o replantearme con la escritura... es su teoría del distanciamiento . . . Eso me interesa mucho, y sobre todo distanciamiento en el sentido de la representación. La obra de Ramón del Valle-lnclán es totalmente distinta de la obra de Bertolt Brecht, y sin embargo tienen un punto...

Vasserot, Christilla

1995-10-01

74

Planificación Neuroquirúrgica con Software Osirix  

PubMed Central

Introducción: La individualidad anatómica es clave para reducir el trauma quirúrgico y obtener un mejor resultado. Actualmente, el avance en las neuroimágenes ha permitido objetivar esa individualidad anatómica, permitiendo planificar la intervención quirúrgica. Con este objetivo, presentamos nuestra experiencia con el software Osirix. Descripción de la técnica: Se presentan 3 casos ejemplificadores de 40 realizados. Caso 1: Paciente con meningioma de la convexidad parasagital izquierda en área premotora; Caso 2: Paciente con macroadenoma hipofisario, operada previamente por vía transeptoesfenoidal en otra institución con una resección parcial; Caso 3: Paciente con lesiones en pedúnculo cerebeloso medio bilateral. Se realizó la planificación prequirúrgica con el software OsiriX, fusionando y reconstruyendo en 3D las imágenes de TC e IRM, para analizar relaciones anatómicas, medir distancias, coordenadas y trayectorias, entre otras funciones. Discusión: El software OsiriX de acceso libre y gratuito permite al cirujano, mediante la fusión y reconstrucción en 3D de imágenes, analizar la anatomía individual del paciente y planificar de forma rápida, simple, segura y económica cirugías de alta complejidad. En el Caso 1 se pudo analizar las relaciones del tumor con las estructuras adyacentes para minimizar el abordaje. En el Caso 2 permitió comprender la anatomía post-operatoria previa del paciente, para determinar la trayectoria del abordaje transnasal endoscópico y la necesidad de ampliar su exposición, logrando la resección tumoral completa. En el Caso 3 permitió obtener las coordenadas estereotáxicas y trayectoria de una lesión sin representación tomográfica. Conclusión: En casos de no contar con costosos sistemas de neuronavegación o estereotáxia el software OsiriX es una alternativa a la hora de planificar la cirugía, con el objetivo de disminuir el trauma y la morbilidad operatoria. PMID:25165617

Jaimovich, Sebastián Gastón; Guevara, Martin; Pampin, Sergio; Jaimovich, Roberto; Gardella, Javier Luis

2014-01-01

75

Crater-lake Santa Maria del Oro as a Pristine Reference for Persistent Organic Pollutants (POP' s) and Heavy Metals Content in Environmental Investigations in Western Mexico (Project Conacyt-Semarnat 2002-C01-0463, in Progress).  

NASA Astrophysics Data System (ADS)

Santa Maria del Oro Lake ( SMO) (21.37° N, 104.57° W; 750 m a.s.l.) is a quaternary crater-lake located at western Mexico in the natural border between two geological provinces: the plio-quaternary Trans-Mexican Volcanic Belt and the oligo-miocenic silicic volcanic province Sierra Madre Occidental. SMO, a tropical freshwater lake, is a warm-monomictic lake having a diameter of ca. 2 km and a mean depth at the depocenter of ca. 60 m, where three benthos cores were recovered. Contents of POP' s, total inorganic carbon (TIC), total organic carbon (TOC) and heavy metals were analyzed. Geochemistry and mineralogy also were studied in shallow sediments which corresponded to the decade of 50-60's, otherwise the beginning of industrial development of central Mexico; which is considered the possible source of emission of POP' s and heavy metals. Dioxin, furan, plaguicides and PCB' s contents were analyzed by a GC-MS applying USEPA methods. In the first 40 cm (n= 20) of the sedimentary column ( SC) the absence of POP' s was evidenced, applying a method detection limit ( MDL) of 5 ? g/ml for dioxin, furan and PCB' s. For plaguicides like chlordane and toxaphene the MDL was 0.5 ? g/ml and for plaguicides like DDT, aldrin, endrin, dieldrin, heptachlore and mirex the MDL was 5 ? g/ml. The MDL for HCB was 1 ? g/ml. The average (n= 30) for TIC, TOC and total carbon (TC) for the first 40 cm of the SC is as follows: TIC 2.4 %, TOC 3.7 % and TC 6.12 %. The average (n= 20) content (in ppm) of heavy metals for the first 20 cm of the SC is as follows: As 5.97, Cr 27.54, Cu 16.31, Ni 12.29, Pb 21.35 and Zn 82.46. These contents are roughly similar to the clarke of these metals in volcanic rocks. After the criteria of severe effect level ( SEL) of heavy metal in sediments, the content of these metals is below SEL levels. These results permit us to conclude that the sediments of SMO can be considered in unaffected state with respect to antropogenic contamination like POP' s and heavy metals. Consequently, Santa Maria del Oro Lake can be considered as a pristine reference in paleo-ecological and environmental investigations in western Mexico.

Zarate-Del Valle, P. F.; Gomez-Hermosillo, C. M.; Venegas-Garcia, D. J.

2007-12-01

76

Quick Chili Con Carne Ingredients  

E-print Network

Quick Chili Con Carne Ingredients: 16 ounces kidney beans, canned 1 pound ground turkey 1/2 onion 1 is cooking, cut the ends off of the onion, and peel off the brown layers. Cut onion in half and place flat side down. Slice into thin strips keeping onion together. Turn and slice again to dice. 4. Slice green

Liskiewicz, Maciej

77

[CONs].  

PubMed

In 2012, USA Preventive Services Task Force revised the guidelines for prostate cancer screening and recommended against prostate specific antigen(PSA)-based screening for prostate cancer for all age groups. This revision had a great impact worldwide. Immediately after the announcement, many expert societies expressed disagreement with this revision, but some of these have gradually come to accept it. When multiple organizations develop guidelines for a particular topic, the recommendations may differ. In this regard, the "standards for developing trustworthy clinical practice guidelines" presented in the report by the Institute of Medicine, will be helpful. The number of cases and the incidence rates of prostate cancer have been rapidly increasing in Japan, especially in the elderly population. Accordingly, sufficient information needs to be provided for appropriate decision-making, considering the balance between the risks and benefits, if cancer screening in the elderly population is to be implemented. PMID:24917002

Sobue, Tomotaka

2014-05-01

78

Computacion inteligente con organismos vivos  

E-print Network

resoluci´on. 2 / 37 #12;Computaci´on y M´aquinas ... VIVAS e INTELIGENTES 3 / 37 #12;Modelo de computaci tediosas... ... y otras tareas inteligentes. 7 / 37 #12;M´aquinas de prop´osito espec´ifico Desde el ´abacoComputaci´on inteligente con organismos vivos Mario de Jes´us P´erez Jim´enez Grupo de Investigaci

Jiménez, Mario de J. Pérez

79

todasuvida: Las personas con diabetes son ms  

E-print Network

diabetes Controlesu todasuvida: Las personas con diabetes son más propensas a padecer de enfermedades del corazón que quienes no tienen diabetes. Boletín 631 D Las personas con diabetes tienen mayor- res relacionados con la diabetes, como derrame cerebral, mala circulación en las piernas y pies e

80

El Futuro de los Recursos Pesqueros Marinos  

NSDL National Science Digital Library

If we do not act soon, many marine fish species will disappear. To address this potential catastrophe, we need to reduce overfishing, destructive fishing practices, and ecosystem pollution. The English version is found at http://www.actionbioscience.org/biodiversity/duffy.html.

J. Emmett Duffy (Virginia Institute of Marine Science;)

2010-03-28

81

¡Truco Con Agua!  

NSDL National Science Digital Library

En esta actividad los aprendices aprenderán un truco de magia donde la magia es la presión del aire. Los participantes tomarán un vaso de agua medio lleno y lo taparán con un pedazo de plástico o cartón. Sosteniendo la tarjeta contra el vaso, lo voltearán boca abajo y cuando quiten la mano debajo del vaso, ¡abracadabra! no se caerá el agua. En la tira cómica, Mateo explica a los aprendices que la presión que hace el aire en todas las direcciones es la que sostiene la tarjeta.

Science, Lawrence H.

2009-01-01

82

Opciones de cirugía para mujeres con CDIS o con cáncer de seno  

Cancer.gov

Contiene información sobre los tipos de cirugía de seno, como la operación para conservar el seno y la mastectomía, y ayuda a las mujeres diagnosticadas con CDIS o con cáncer de seno a decidir cuál cirugía es la más conveniente para ellas.

83

INFECCION POR CITOMEGALOVIRUS CON COMPROMISO HEPATICO EN ADULTOS INMUNOCOMPETENTES  

Microsoft Academic Search

Resumen Evaluamos retrospectivamente a 73 adultos inmunocompetentes que consultaron entre marzo de 1999 y marzo de 2004 a un centro infectológico ambulatorio por fiebre y astenia, con elevación discreta de las transaminasas y serología compatible con infección reciente por citomegalovirus (CMV). Excluimos a pacientes con antecedentes de transfusiones, adicciones e inmunodeficiencias, así como aquellos con altera- ciones hepáticas preexistentes o

CLAUDIA VUJACICH; GABRIELA VIDIELLA; LAURA BARCELONA; EDGARDO STURBA; DANIEL STAMBOULIAN

84

iCons, 2011 Cholera in Haiti  

E-print Network

© iCons, 2011 Cholera in Haiti Handouts: 1. 1-page explainer of cholera outbreak in Haiti Assignments Part 1: Developing an Explainer 1. In-class written assignment of societal challenge with cholera in Haiti 2. In-class written assignment of scientific investigation relating to cholera 3. Take

Auerbach, Scott M.

85

InterCon Travel Health: Case B  

ERIC Educational Resources Information Center

InterCon provides services to health insurers of foreign tourists who travel to the United States and Canada. Management wants to implement a new information system that will deal with several operational problems, but it is having difficulty securing the capital resources to fund the system's development. After an initial failure, the chief…

Truman, Gregory E.; Pachamanova, Dessislava A.; Goldstein, Michael A.

2010-01-01

86

CON Advising Academic Year 2013-2014  

E-print Network

' personal, academic, and career goals. This advisor/student partnership requires participationCON Advising Academic Year 2013-2014 Advisors: Rita Tower Kelly Fanning Office: Garrand 403 Garrand students to make decisions about their academic, personal and professional pathways, and to encourage

Carter, John

87

LA MAESTRA EN CIENCIAS (NEUROBIOLOGA), Con el objetivo de formar profesionales con conocimientos slidos de los  

E-print Network

LA MAESTRÍA EN CIENCIAS (NEUROBIOLOGÍA), Con el objetivo de formar profesionales con conocimientos, neurociencias, psicobiología, física, matemáticas, estadística y metodología de la ciencia, a presentar su Nacional de Posgrado de Calidad del Consejo Nacional de Ciencia y Tecnología en categoría: COMPETENTE

Islas, León

88

Insercin y fusin con listas ordenadas: un ejemplo de razonamiento automtico con ACL2  

E-print Network

Inserción y fusión con listas ordenadas: un ejemplo de razonamiento automático con ACL2 F. Palomo formales, razonamiento automático, len- guaje de programación aplicativo, ACL2, NQTHM Resumen En este artículo presentamos un ejercicio de formalización y demostración automática en ACL2, un sistema de

Alonso, José A.

89

Watch Globally, Think Locally CON-CAN Movie Festival  

E-print Network

CORTO TOKYO 2010 Watch Globally, Think Locally 12 18 12 19 12 20 70 CON-CAN Movie Festival CON-CAN Movie Festival Presents www.con-can.com #12;90 COMPETITION 1 : Play Expression COMPETITION 2 : Twilight TOKYO 2010 CON-CAN Movie Festival 151-0051 4-14-4 SK 4F Tel: 03-5414-6532 E-mail : cortokyo

Kasahara, Hironori

90

Feature Speci cation and Automatic Con ict Detection  

E-print Network

Feature Speci#12;cation and Automatic Con ict Detection #3; Amy P. Felty y Kedar S. Namjoshi School of automatically detecting feature con icts (\\undesirable inter- actions") at the speci#12;cation stage. Early con ict detection can help prevent costly and time-consuming problem #12;xes during implementa- tion

Felty, Amy

91

The evolution of female mate choice by sexual con ict  

E-print Network

The evolution of female mate choice by sexual con ict Sergey Gavrilets1* , Go« ran Arnqvist2 a quantitative genetic model showing that sexual con£ict over mating indeed results in the joint evolution. Keywords: sexual selection; sexual con£ict; evolution of female mate choice; mathematical models 1

Gavrilets, Sergey

92

Too Many Minas Spoil The Con  

E-print Network

1 12:08 pm February 13th, 2007 vuirneen A semi-private email to Mina de Malfois Is anyone familiar with the writings of mina_de_malfois? I wrote this email to her, based entirely on her Minaverse, between... midnight and two am last night and I just wanted someone to check it before I send it to her. Too Many Minas Spoil The Con Dear Mina, I'm not quite sure how to start this letter. I feel as though I've failed a test of some kind and that if I only...

2007-02-13

93

Explorando el costo-efectividad de instrumentos basados en el mercado para la mejora de la calidad del agua: una modelación espacial económico-ambiental  

Microsoft Academic Search

El uso agrícola de la tierra en cuencas costeras conduce a la contaminación del agua y degradación subsecuente de recursos costeros y marinos. Para asegurar el desarrollo económico sostenible de las regiones costeras, es necesario balancear los beneficios marginales de la contaminación (agrícola) del agua con los costos marginales asociados a la degradación de los recursos costeros y marinos. La

Peter C. Roebeling; Martijn E. van Grieken

2009-01-01

94

Enriquecimiento del pienso de dorada con quitina y paredes de levaduras con fines preventivos  

Microsoft Academic Search

Preventive dietary supplements of chitin and yeast wall in gilthead seabream To determine the immunomodulatory effect of the dietary intake of commercial chitin and yeast cell walls in gilthead seabream, Sparus auratus Linnaeus, 1758, specimens were fed diets containing different con- centrations of chitin or yeast cell walls for 1, 2, 4 or 6 weeks. Subsequently, their main humoral (lysozyme

A. Rodríguez; M. A. Esteban; A. Cuesta; J. Ortuño; J. Polaina; J. Meseguer

95

Con ict-free colorings J anos Pach  

E-print Network

Con ict-free colorings J#19;anos Pach G#19;eza T#19;oth Abstract A coloring of the elements of a planar point set P is said to be con ict-free if, for every closed disk D whose intersection with P, and Smorodinsky by showing that any con ict-free coloring of every set of n points in the plane uses at least c

Pach, János

96

Tiene familiares con Alzheimer? La Escuela de Medicina del Recinto de Ciencias Mdicas en colaboracin con la Universidad de Columbia  

E-print Network

¿Tiene familiares con Alzheimer? 25/1/2008 La Escuela de Medicina del Recinto de Ciencias Médicas más con Alzheimer para participar de un estudio genético. La investigación pretende encontrar genes que se encuentren relacionados a la enfermedad de Alzheimer con el propósito de aprender más sobre las

Quirk, Gregory J.

97

MARINO RECREATION CENTER Monday, July 5 Monday, July 12, 2010  

E-print Network

:30pm Closed: Judo Club 9:30pm ­ 11:45pm Open Thursday 5:00am ­ 11:45am Open 11:45am ­ 1:00pm Closed Closed: Judo Club 9:30pm ­ 11:45pm Open Friday 5:00am ­ 11:45pm Open Saturday 8:00am ­ 8:45pm Open #12/12) 5:00am ­ 6:00pm Open 6:00pm ­ 7:30pm Closed: Group Fitness Class 7:30pm ­ 9:30pm Closed: Judo Club 9

Sridhar, Srinivas

98

Humanities 3 LEARNING IN THE MEDIEVAL UNIVERSITY Prof. J. Marino  

E-print Network

the student for ad- vanced work in law and medicine as well as theology. Based primarily upon Aristotle nature, was the path to wisdom. Undergraduate textbooks were Aristotle's logic (Organon), works on gram, and burnished by rhetoric, but only theology can use it." The overwhelming domination of Aristotle

Russell, Lynn

99

October 6, 1997 ITER L-Mode Con nement Database  

E-print Network

October 6, 1997 ITER L-Mode Con nement Database S.M. Kaye and the ITER Con nement Database Working Group Abstract This paper describes the content of an L-mode database that has been compiled with data, and Tore-Supra. The database consists of a total of 2938 entries, 1881 of which are in the L-phase while

100

VENTAJAS DEPORTIVAS ENTIDADES COLABORADORAS CON EL SERVICIO DE DEPORTES  

E-print Network

VENTAJAS DEPORTIVAS ENTIDADES COLABORADORAS CON EL SERVICIO DE DEPORTES WHITE PEPPER Pub DEPORTES #12;Alicante C.F. universitaria que sean titulares de la TIU. Organización conjunta de actividades Universitarios que anualmente convoca el Consejo Superior de Deportes, a aquellos jugadores que cumplan con los

Escolano, Francisco

101

RoboCon: A general purpose telerobotic control center  

SciTech Connect

This report describes human factors issues involved in the design of RoboCon, a multi-purpose control center for use in US Department of Energy remote handling applications. RoboCon is intended to be a flexible, modular control center capable of supporting a wide variety of robotic devices.

Draper, J.V.; Noakes, M.W. [Oak Ridge National Lab., TN (United States). Robotics and Process Systems Div.; Schempf, H. [Carnegie Mellon Univ., Pittsburgh, PA (United States); Blair, L.M. [Human Machine Interfaces, Inc., Knoxville, TN (United States)

1997-02-01

102

Control del dolor: Apoyo para las personas con cáncer  

Cancer.gov

Contiene información sobre las medicinas contra el dolor para pacientes con cáncer, los planes para controlarlo, cómo hablar con su equipo de atención médica sobre el dolor que usted siente y qué hacer para controlar los efectos físicos y emocionales del mismo.

103

-okfl ^ ORNL/CON-172 Linear Harmonic Analysis of Free-  

E-print Network

-okfl ^ ORNL/CON-172 OAK RIDGE NATIONAL LABORATORY Linear Harmonic Analysis of Free- Piston. #12;ORNL/CON-172 Engineering Technology Division* LINEAR HARMONIC ANALYSIS OF FREE-PISTON STIRLING/dynamic problem that is associated with a free-piston Stirling engine (FPSE). The governing equations

Oak Ridge National Laboratory

104

Introduzione alla programmazione client-side (con Javascript)  

E-print Network

1 MODULO 2 PARTE 4 Introduzione alla programmazione client-side (con Javascript) Goy - a.a. 2009/2010 Programmazione Web client side (con Javascript) 1 · Javascript è un linguaggio di scripting, tipicamente Javascript · Come tutti i linguaggi di scripting, è interpretato: il sorgente non deve essere compilato per

Goy, Anna

105

Introduzione alla programmazione client-side (con Javascript)  

E-print Network

1 MODULO 2 PARTE 4 Introduzione alla programmazione client-side (con Javascript) Goy - a.a. 2012/2013 Programmazione Web client side (con Javascript) 1 Il fil rouge del MODULO 2 PARTE 4: Introduzione alla progr. client-side · Javascript · DOM e gestori di eventigli oggetti del DOM... PARTE 5: Programmare sul Web 2

Goy, Anna

106

Introduzione alla programmazione client-side (con Javascript)  

E-print Network

1 MODULO 2 PARTE 4 Introduzione alla programmazione client-side (con Javascript) Goy - a.a. 2011/2012 Programmazione Web client side (con Javascript) 1 Il fil rouge del MODULO 2 PARTE 4: Introduzione alla progr. client-side · Javascript · DOM e gestori di eventigli oggetti del DOM... PARTE 5: Programmare sul Web 2

Goy, Anna

107

Introduzione alla programmazione client-side (con Javascript)  

E-print Network

1 MODULO 2 PARTE 4 Introduzione alla programmazione client-side (con Javascript) Goy - a.a. 2010/2011 Programmazione Web client side (con Javascript) 1 · Javascript è un linguaggio di scripting, tipicamente Javascript · Come tutti i linguaggi di scripting, è interpretato: il sorgente non deve essere compilato per

Goy, Anna

108

Con Edison Commercial and Industrial Energy Efficiency Program  

E-print Network

1 Con Edison Commercial and Industrial Energy Efficiency Program Discussion Overview ? Benefits, Eligibility & Team Members ? Program Components ? Project Incentives & Energy Studies ? Additional Program Attributes, Tools & Resources... ? Process Overview ? FAQ ? Q&A 2 Benefits For the Con Edison Customer ? Reduced Replacement Costs ? Identify EE Opportunities ? Reduced Operating Costs ? Infrastructure/Value Enhancements ? Carbon Footprint Reduction ? Codes/LEED/Energy Star...

Pospisil, D.

2011-01-01

109

Breath Analysis Science at PittCon 2012, Orlando, Florida  

EPA Science Inventory

Breath analysis science was featured in three organized sessions at this year?s Pittsburgh Conference and Exposition, or ?PittCon 2012? (http://www.pittcon.org/). As described in previous meeting reports, PittCon is one of the largest international conferences for analytical chem...

110

Cálculos ab initio con correlación electrónica  

NASA Astrophysics Data System (ADS)

Estamos entrando en una era donde la ortogonalidad entre las investigaciones de carácter experimental y de naturaleza teórica se irá difuminando progresivamente y la problemática a resolver quedará en escena como el único actor principal de la obra. Como premisa para una cooperación teórico-experimental de igual a igual, la metodología químico-cuántica utilizada debe ser capaz de ofrecer resultados de carácter predictivo. Sin duda, esta madurez en la metodología químico-cuántica ya la hemos alcanzado hace algunos años, tal y como muestra entre otras muchas, la labor que nuestro grupo ha realizado en el transcurso de la última década, dentro del campo de la Espectroscopía Teórica. Los estudios realizados comprenden una amplia gama de sistemas, variando tanto en tamaño como en complejidad, abordando problemáticas espectroscópicas consideradas tradicionalmente como especialmente controvertidas. Nuestra contribución científica más relevante reside en el carácter cuantitativo de las asignaciones espectroscópicas que hemos propuesto en base a resultados ab initio. Recordemos que en los años noventa los resultados ab initio solían presentar para las energías de excitación de sistemas de tamaño molecular moderado, como el benceno, errores de más de 1 eV. En comparación con el éxito relativo de los métodos semiempíricos, la frustración de la metodología ab initio quedaba todavía más patente. Los estudios que hemos presentado representan una comprensión profunda de los espectros electrónicos en sistemas orgánicos claves, mostrando el camino a seguir para obtener asignaciones espectroscópicas precisas (entre 0.1-0.2 eV). La naturaleza del método CASPT2 junto al diseño de estrategias computacionales nos ha permitido alcanzar el carácter cuantitativo con el que se caracterizan nuestras contribuciones[1,2]. Por todo ello, algunos de los trabajos publicados se consideran clásicos dentro del campo, pues en cierto modo definen el campo, y se reflejan en libros publicados recientemente. En la conferencia se analizarán ciertos pormenores de las investigaciones realizadas. El tipo de aplicaciones llevadas a cabo hasta la fecha se ilustrará mediante el estudio teórico del espectro electrónico de ciclooctatetraeno. Dando un paso más en la evolución de nuestra investigación, pretendemos en la actualidad describir, desde un formalismo teórico y al mismo nivel de exigencia, los mecanismos subyacentes que tienen lugar en las reacciones biológicas fototoinducidas, es decir, reacciones que se inician mediante la absorción de luz[3]. Como muestra de la caracterización de los procesos fotofísicos y fotoquímicos en fotobiología teórica, hemos elegido la descripción de la conversión interna ultrarrápida que tiene lugar en los cromóforos del ADN. Los estados excitados de las moléculas de los ácidos nucleicos presentan tiempos de vida media que se encuentran en el rango de sub-picosegundos, sugiriendo la presencia de un canal ultrarrápido de conversión interna, lo que normalmente se asocia en la fotoquímica contemporánea a una intersección cónica entre el estado excitado y el fundamental[4]. De esta forma nuestro ADN previene de forma eficaz posibles reacciones en el estado excitado y se revela como un excelente protector solar.

Merchán Bonete, M.

111

Manejo anestésico en la corrección toracoscópica de atresia de esófago tipo I con ventilación unipulmonar con modalidad de flujo continuo  

Microsoft Academic Search

Resumen Describimos el modo de ventilación con flujo conti- nuo para la reparación de un caso de atresia de esófa- go tipo I en un lactante. Este tipo de atresia se carac- teriza por estenosis esofágica distal, con bolsón proximal sin fístula en el árbol bronquial. Las técni- cas clásicas quirúrgicas realizan la reparación por toracotomía, pero la nueva introducción

F. García-Montoto; F. Martínez; N. Falcone; I. Cano; P. Rubio

112

DESAFÍOS ÉTICOS DE LA INVESTIGACIÓN CON ANIMALES, MANIPULACIÓN GENÉTICA  

PubMed Central

En la investigación con animales existen cuestionamientos éticos tanto en el uso como modelos de enfermedades humanas y requisito previo para ensayos en humanos como en la introducción de modificaciones genéticas. Algunos de estos cuestionamientos son: no representar exactamente la condición humana como modelos, realizar pruebas de toxicidad con grave daño para los animales, alterar su naturaleza mediante modificaciones genéticas, riesgos de la introducción de organismos genéticamente modificados. El uso de animales en investigación para beneficio humano, impone al ser humano la responsabilidad moral de respetarlo, no haciéndoles sufrir innecesariamente, al estar trabajando con seres vivientes y sentientes. PMID:23338641

Yunta, Eduardo Rodríguez

2012-01-01

113

9 CFR 319.301 - Chili con carne with beans.  

Code of Federal Regulations, 2011 CFR

...301 Section 319.301 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE...OR COMPOSITION Canned, Frozen, or Dehydrated Meat Food Products § 319.301 Chili con carne with...

2011-01-01

114

Control del dolor: Apoyo para las personas con cáncer  

Cancer.gov

Libro sobre el control del dolor en pacientes con cáncer. Cubre los métodos y medicinas, así como los efectos físicos y emocionales del dolor. Es una adaptación cultural para el público de habla hispana del libro en inglés Pain Control.

115

iCons, 2011 Alzheimers and Aluminum: Lesson Plan  

E-print Network

© iCons, 2011 Alzheimers and Aluminum: Lesson Plan Handouts to explore mechanistic link between Alzheimer's and aluminum 5. Brief proposal expanding Points to Aluminum's Link With Alzheimer's Disease" from 1989. Provide handout

Auerbach, Scott M.

116

DOE/ORO/2092 ANNUAL SITE ENVIRONMENTAL DATA  

E-print Network

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1-31 Y-12 Plant 2.1 Y-12 Plant Biomonitoring Program summary information for wastewater treatment NPDES Permit Number TN 0002950 Discharge Point 005, Sewage Treatment Plant . . . . . 1-15 1.3 1998 NPDES-1203 (sewage treatment plant

Pennycook, Steve

117

Osseointegrated implants in oro-dental and facial prosthetic rehabilitation.  

PubMed

A basic prerequisite for establishing true and lasting tissue integration of a nonbiologic prosthesis is the minimal risk of adverse local or general tissue reactions. It consists of a detailed understanding of the response behavior of highly differentiated hard and soft tissues to the surgical preparation of a recipient site and the installation of the prosthesis, as well as long-term tissue adaptation and the functional demands on the anchorage unit. The complex arrangement of titanium implant material, surface physics, and biocompatibility with the host tissues will be reviewed in this article. PMID:7816431

Holt, G R

1994-10-01

118

Plasma Cell Mucositis of Oro- and Hypopharynx: A Case Report  

PubMed Central

Objective. To raise awareness of plasma cell mucositis as a rare differential diagnosis for oral mucosal ulceration and its macroscopic similarity to malignancy. Method. We report a patient who presented with oral features suggestive of malignancy. A biopsy revealed plasma cell mucositis. Results. The patient successfully had a full excision of one lesion and a spontaneous resolution of the other. Conclusion. With the increasing incidence of oral mucosal pathology, physicians should be aware of this differential diagnosis. PMID:22953106

Puvanendran, Mark; Lieder, Anja; Issing, Wolfgang

2012-01-01

119

DOE/ORO/2185 Oak Ridge Reservation Annual Site  

E-print Network

published: September 2004 Prepared by Oak Ridge National Laboratory P.O. Box 2008, Oak Ridge, TN 37831 Technical coordinators Wayne McMahon Joan Hughes Mike Coffey Oak Ridge Y-12 Complex Oak Ridge National and by the Y-12 National Security Complex Oak Ridge, TN 37831-8169 Managed by BWXT Y-12, L.L.C. for the U

Pennycook, Steve

120

DOE/ORO/2159 Oak Ridge Reservation Annual Site  

E-print Network

: September 2003 Prepared by Oak Ridge National Laboratory P.O. Box 2008, Oak Ridge, TN 37831-2008 Managed . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1-12 1.6.3 Oak Ridge National Laboratory . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Technical coordinators Wayne McMahon Joan Hughes Mike Coffey Oak Ridge Y-12 Complex Oak Ridge National

Pennycook, Steve

121

DOE/ORO/2119 Oak Ridge Reservation Annual Site  

E-print Network

. Mulkey Date published: September 2001 Prepared by Oak Ridge National Laboratory P.O. Box 2008, Oak Ridge . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1-13 1.6.3 Oak Ridge National Laboratory . . . . . . . . . . . . Technical coordinators L. W. McMahon J. F. Hughes M. L. Coffey Oak Ridge Y-12 Complex Oak Ridge National

Pennycook, Steve

122

DOE/ORO/2218 Oak Ridge Reservation Annual Site  

E-print Network

: September 2006 Prepared by Oak Ridge National Laboratory P.O. Box 2008, Oak Ridge, TN 37831-2008 Managed Technical coordinators Wayne McMahon Joan Hughes Mike Coffey Oak Ridge Y-12 Complex Oak Ridge National National Security Complex Oak Ridge, TN 37831-8169 Managed by BWXT Y-12, L.L.C. for the Department

Pennycook, Steve

123

Oak Ridge ReseRvatiOn DOE/ORO/2379  

E-print Network

Creative Media Human Resources and Communications Oak Ridge National Laboratory The Oak Ridge Reservation Oak Ridge National Laboratory East Tennessee Technology Park Electronic publisher Coordinating editors Judy Neeley, Jane Parrott, Andy Sproles September 2011 Prepared by Oak Ridge National Laboratory P

Pennycook, Steve

124

[Oro-facial-digital syndrome type I: phenotypic variable expression].  

PubMed

Oral-facial-digital syndrome type 1 (OFD1; OMIM #311200) is a developmental disorder transmitted as an X-linked dominant condition with embryonic male lethality. It is associated with malformation of the oral cavity, face, and digits. Furthermore, it is characterized by the presence of milia, hypotrichosis and polycystic kidney disease. We present two cases with clinical diagnosis of oral-facial-digital syndrome type I with some phenotypic variability between them. PMID:25362921

Boldrini, María Pía; Giovo, María Elsa; Bogado, Claudia

2014-12-01

125

Multilevel Annotation in SpeeCon Polish Speech Database  

Microsoft Academic Search

\\u000a SpeeCon Polish Speech Database was collected within the framework of the SpeeCon project partially sponsored by the EC (IST-1999-10003).\\u000a The database contains two sets of data, which comprise 550 adults’ recording sessions and 50 sessions from children, respectively.\\u000a The adult speakers were recorded in various environments: offices, living rooms, cars and public places. Recordings contain\\u000a free spontaneous speech passages, elicited

Krzysztof Marasek; Ryszard Gubrynowicz

2004-01-01

126

El teatro como reflexión colectiva: Conversación con Sergio Corrieri  

E-print Network

SPRING 1983 51 El teatro como reflexión colectiva: Conversación con Sergio Corrieri Gerardo Luzuriaga Sergio Corrieri es el director del renombrado Teatro Escambray, fundado por él y otros teatristas de La Habana en 1968 en la región del... propios del subdesarrollo. La superstición, por ejemplo, muy extendida en nuestras zonas rurales; el reparo del campesino, sus dudas ante la colectivización del trabajo agrícola, ante el hecho de unir sus esfuerzos con los de otros campesinos, y en...

Luzuriaga, Gerardo

1983-04-01

127

Teaching after Retirement: The Pros and the Cons  

ERIC Educational Resources Information Center

Having enjoyed teaching during my active career, I continued to teach summer school following retirement. Self-observed sensory and cognitive impairments, although not mentioned by students in their evaluations, induced me to consider the pros and cons of continuing to teach. My hope is that this list of benefits and problems will be of assistance…

Sommer, Robert

2014-01-01

128

Redes Reconfigurables Controladas por Marcado: Redes de Petri con Cambios  

E-print Network

Redes Reconfigurables Controladas por Marcado: Redes de Petri con Cambios Din´amicos Estructurales a cambios din´amicos utilizando exten- siones de redes de Petri. En estudios previos, hemos introducido los siste- mas de reescritura de redes y una subclase de los mismos llamada redes reconfigurables. En un

Alpuente, María

129

con Diabetes Su diabetes s se puede controlar!  

E-print Network

Do Well, Be Well con Diabetes ¡Su diabetes sí se puede controlar! Educational programs of the Texas, and the County Commissioners Courts of Texas Cooperating. to develop diabetes self-care skills, to improve eating habits and maintain good nutrition, to increase physical activity, to prevent diabetes complications

130

Providers debate pros and cons of pneumonia vaccination at discharge.  

PubMed

When to vaccinate against pneumonia? Does it makes sense when patients are in the hospital? Or should patients wait for the first post-op visit with the PCP? Office-based and hospital-based physicians weigh the pros and cons of each. PMID:11246808

2001-02-01

131

Problemas resueltos de variable compleja con elementos de teoria  

E-print Network

Problemas resueltos de variable compleja con elementos de teor´ia Ignacio Monterde, Vicente Montesinos. #12;´Indice general Introducci´on V 1. Teor´ia elemental 1 1.1. Elementos de teor´ia . . . . . . . . 55 1.2.8. Integraci´on compleja . . . . . . . . . . . . . . . . . . . 57 2. La teor´ia de las

Montesinos Santalucía, Vicente

132

Detail of conning tower atop the submarine. Note the wire ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Detail of conning tower atop the submarine. Note the wire rope wrapped around the base of the tower, which may have been used in an attempt to pull the submarine offshore. - Sub Marine Explorer, Located along the beach of Isla San Telmo, Pearl Islands, Isla San Telmo, Former Panama Canal Zone, CZ

133

ConNexus to awarenex: extending awareness to mobile users  

Microsoft Academic Search

We explored the use of awareness information to facilitate communication by developing a series of prototypes. The ConNexus prototype integrates awareness information, instant messaging, and other communication channels in an interface that runs on a desktop computer. The Awarenex prototype extends that functionality to wireless handheld devices, such as a Palm. A speech interface also enables callers to make use

John C. Tang; Nicole Yankelovich; James Begole; Max Van Kleek; Francis C. Li; Janak R. Bhalodia

2001-01-01

134

Un estudio eto-espacial con variables ambientales  

Microsoft Academic Search

La dinámica eto-espacial, en función de la variable ambiental, es un estudio desde el Enfoque paradigmático de la Psicología Ambiental. Se ha desarrollado en el foso de papiones sagrados (hamadryas) y anubis del Zoológico de Barcelona. Se han estudiado las posibles influencias del medio ambiente con respecto a la conducta, tanto en el contexto espacial como social. Se han utilizado

Josep Maria Amenós i Vidal; Joan Josep Tharrats i Pascual

1984-01-01

135

Peces asociados con la deriva de macroalgas en Aysén, Chile  

Microsoft Academic Search

Resumen.- La obtención de restos de macroalgas flotando a la deriva en aguas frente al sur de Chile permite, por primera vez, explorar la presencia de peces nadando junto con ellas. Se registra la presencia del pez aguja Leptonotus blainvilleanus (familia Syngnathidae); la cojinova Seriolella porosa (familia Centrolophidae); el pampanito, Stromateus stellatus (familia Stromateidae) y el torito Bovichtus sp. (familia

Germán Pequeño; Daniela Farías; Martín Thiel; Iván Hinojosa

2004-01-01

136

ortl ORNL/CON-309 AN ASSESSMENT OF  

E-print Network

Meckler Associates, P.C. July 1992 Prepared by the OAK RIDGE NATIONAL LABORATORY Oak Ridge, Tennessee RIDGE NATIONAL LABORATORY Oak Ridge, Tennessee 37831-6285 managed by MARTIN MARIETTA ENERGY SYSTEMS, INCortl ORNL/CON-309 AN ASSESSMENT OF DESICCANT COOLING OAK RIDGE AND NATIONAL DEHUMIDIFICATION

Oak Ridge National Laboratory

137

Cómo hacer las gestiones con su plan de salud  

Cancer.gov

Hay formas de saber si su plan de salud cubre los costos de atención médica de rutina durante un estudio clínico. Esta información puede servirle para saber con quién comunicarse para solicitar ayuda, preguntas que puede hacer y la información que debe recoger y guardar si decide participar en un estudio clínico.

138

Pointwise convergence rate for nonlinear con servation laws  

E-print Network

convergence rate in this case is upper bounded by ku ffl (\\Delta; t) \\Gamma u(\\Delta; t)k L 1 Ÿ const.ffl: (6Pointwise convergence rate for nonlinear con­ servation laws Eitan Tadmor and Tao Tang Abstract. We finitely many shocks. It is well­known that u ffl (\\Delta; t) converges strongly in L 1 to u(\\Delta; t

Tang, Tao

139

Neogene sequence stratigraphy, Nam Con Son Basin, offshore Vietnam  

Microsoft Academic Search

An integrated well log, biostratigraphic, and seismic stratigraphic study of Miocene to Recent deltaic sediments deposited in the Nam Con Son Basin offshore from southern Vietnam shows the influence of eustacy and tectonics on sequence development. Sediments consist of Oligocene non-marine rift-basin fill (Cau Formation), early to middle Miocene tide-dominated delta plain to delta front sediments (TB 1.5 to TB

K. J. McMillen; E. K. Lee; S. S. Hong

1996-01-01

140

TIRO CON ARCO NIVEL II: AVANZADO (3 CONVOCATORIAS) DESCRIPCIN  

E-print Network

las armas de fuego quedó obsoleto y relegado al uso deportivo o de ocio. Como deporte, formó parte de a dianas situadas a 70 metros de distancia. También es deporte paralímpico desde los Juegos Paralímpicos de Tiro con Arco, puede tener un gran interés para la comunidad universitaria: · Porque es un deporte

Escolano, Francisco

141

TIRO CON ARCO NIVEL I: INCICIACIN (2 CONVOCATORIAS) DESCRIPCIN  

E-print Network

aparecer las armas de fuego quedó obsoleto y relegado al uso deportivo o de ocio. Como deporte, formó parte a dianas situadas a 70 metros de distancia. También es deporte paralímpico desde los Juegos Paralímpicos de Tiro con Arco, puede tener un gran interés para la comunidad universitaria: · Porque es un deporte

Escolano, Francisco

142

The Pros and Cons of RFID in Supply Chain Management  

Microsoft Academic Search

This paper presents the pros and cons of using Radio-Frequency IDentification (RFID) in Supply Chain Management (SCM). While RFID has a greater number of benefits than its predecessor, the bar code, it currently comes at a price that many businesses still consider prohibitive. On the one hand, RFID is advantageous because it does not require line-of-sight scanning, it acts to

Katina Michael; Luke Mccathie

2005-01-01

143

Denaturazione termica e meccanica del DNA : teoria a confronto con gli  

E-print Network

Capitolo 3 Denaturazione termica e meccanica del DNA : teoria a confronto con gli esperimenti. DENATURAZIONE TERMICA E MECCANICA DEL DNA : TEORIA A CONFRONTO CON GLI ESPERIMENTI della transizione DNA B-DNA d

Cocco, Simona

144

Métodos con información genética para abordar la complejidad del cáncer de pulmón  

Cancer.gov

Se estima que 220 000 personas recibieron un diagnóstico de alguna forma de cáncer de pulmón en 2010. Es la principal causa de muertes relacionadas con el cáncer, con más de 157 000 muertes previstas en 2010.

145

Recursos relacionados con los exámenes de detección del cáncer de cuello uterino  

Cancer.gov

El NCI tiene información completa y de base científica sobre prevención, exámenes selectivos de detección, diagnóstico, tratamiento, genética y cuidados de apoyo relacionados con el cáncer. Nuestros especialistas en información pueden responder preguntas relacionadas con el cáncer, entre ellas, las que tienen que ver con los exámenes de detección y el tratamiento del cáncer de cuello uterino. Puede comunicarse con nosotros por teléfono, correo electrónico o mensajería instantánea (el chat solo está disponible en inglés).

146

Accesibilidad para personas con debilidad motriz Mac Os X Snow Leopard  

E-print Network

Accesibilidad para personas con debilidad motriz Mac Os X Snow Leopard ASIC ­ 18 de noviembre de 2010 Pág. 1 de 9 GUÍA DE ACCESIBILIDAD PARA PERSONAS CON DEBILIDAD MOTRIZ EN ENTORNO MAC OS X SNOW para personas con debilidad motriz Mac Os X Snow Leopard ASIC ­ 18 de noviembre de 2010 Pág. 2 de 9

Fernández de Córdoba, Pedro

147

Accesibilidad para personas con debilidad auditiva Mac OS X Snow Leopard  

E-print Network

Accesibilidad para personas con debilidad auditiva Mac OS X Snow Leopard ASIC ­ 18 de noviembre de 2010 Pág. 1 de 14 GUÍA DE ACCESIBILIDAD PARA PERSONAS CON DEBILIDAD AUDITIVA EN ENTORNO MAC OS X SNOW LEOPARD MAC OS X Snow Leopard ofrece algunas ayudas para personas sordas o con problemas para escuchar

Fernández de Córdoba, Pedro

148

Las espirales de Fibonacci podran estar relacionadas con la tensin 26/04/2007 Astroseti  

E-print Network

Las espirales de Fibonacci podrían estar relacionadas con la tensión 26/04/2007 Astroseti Las espirales de Fibonacci podrían estar relacionadas con la tensión. La serie de Fibonacci ­ en la cual cada tensión" para crear espirales con la serie de Fibonacci en microestructuras que crecen en laboratorio

Zexian, Cao

149

Sexual con ict and cooperation in butter y reproduction: a comparative study of polyandry  

E-print Network

Sexual con ict and cooperation in butter y reproduction: a comparative study of polyandry hormonesömay each corre- spond to a separate con£ict^cooperation balance between the sexes. Two scenarios. Keywords: nuptial gifts; mating frequency; sexual con£ict; lifetime fecundity 1. INTRODUCTION

Leimar, Olof

150

Modelling Con ict-Resolution Dialogues Fiorella de Rosis, Floriana Grasso, Cristiano Castelfranchi, and Isabella Poggi  

E-print Network

Modelling Con ict-Resolution Dialogues Fiorella de Rosis, Floriana Grasso, Cristiano Castelfranchi play a particu- larly relevant role when agents have to face a con icting situation: impatient, aggressive, polite, persistent, rude: : : people show radically di#11;erent ways of managing con icts

Bari, Università degli Studi di

151

Functional heterogeneity of con ict, error, task-switching, and unexpectedness effects within medial prefrontal cortex  

E-print Network

Functional heterogeneity of con ict, error, task-switching, and unexpectedness effects within Revised 3 August 2010 Accepted 13 August 2010 Available online 20 August 2010 Keywords: ACC Con ict Error cingulate cortex. The proposed theories have included con ict detection, error likelihood prediction

Kastner, Sabine

152

Apoyo a Estudios Geodinamicos con GPS en Guatemala  

NASA Astrophysics Data System (ADS)

El Instituto Geografico Nacional de Guatemala implemento 17 estaciones GNSS en el año 2009, como un proyecto de credito mixto de donacion de equipamiento del Gobierno de Suiza, el cual, este equipamiento de estaciones CORS GNSS es un sistema de recepción y transmisión de datos crudos GPS RInex que utiliza la tecnologia Spider Web de Leica, asi mismo este sistema esta sirviendo para el espablecimiento de un marco geodesico nacional de coordenadas geodesicas oficiales, el cual se calculan u obtienen las velocidades en tiempos temporales programados de las 17 Estaciones CORS. La infraestructura del marco geodesico de Guatemala esta sirviendo de base para las aplicaciones de estudios geodinamicos como el monitoreo de del desplazamiento de las placas tectonicas por medio de un estudio que se inicio en el año de 1999, llamado medicion con GPS el sistema de Fallas de los rios Polochic Motagua de Guatemala, tambien para un estudio que se implemento para deformación de corteza terrestre local en un Volcan Activo de Guatemala llamado Pacaya. Para el estudio de medicion con GPS en el sistema de falla de los Rios del polochic Motagua se implementaron 16 puntos para medir con GPS de dos frecuencias en el año de 1999, el cual, tres puntos son estaciones geodesicas CORS IGS llamados GUAT, ELEN y HUEH, despues en el año de 2003 se hizo otra medicion en un total de 20 puntos, que permitió calcular las velocidades de desplazamieinto de los puntos en mención, usando como referencia el modelo NUVEL 1A de DeMets de la placa de Norteamerica. Este estudio fue en cooperación internacional por la universidad de Nice de Francia y el IGNde Francia. Para el estudio del monitoreo con GPS del volcan activo de Guatemala, se implementaron cuatro puntos al rededor del volcan, el cual, se realizan cuatro mediciones al año, que permiten determinar axialmente la distancias entre los puntos, y rebisar estadisticamente cual es el comportamiento de las distancias en funcion del tiempo, si existen diferencias graduales crecientes o decrecientes, que nos da un indicativo del desplazamiento de la corteza terrestre al rededor del volcan.

Robles, V. R.

2013-05-01

153

Do Well, Be Well with Diabetes 2013 1 Formulario de Registro para Personas con Diabetes Formulario de Registro para Personas con Diabetes 2013  

E-print Network

Do Well, Be Well with Diabetes ­ 2013 1 Formulario de Registro para Personas con Diabetes Formulario de Registro para Personas con Diabetes ­ 2013 Si usted NO TIENE diabetes, por favor NO LLENE este sobre diabetes en el Condado de _______________. D. El código postal en mi casa es __ __ __ __ __. E

154

Do Well, Be Well with Diabetes 2013 1 Formulario de Conclusin para Personas con Diabetes Formulario de Conclusin para Personas con Diabetes 201  

E-print Network

Do Well, Be Well with Diabetes ­ 2013 1 Formulario de Conclusión para Personas con Diabetes Formulario de Conclusión para Personas con Diabetes ­ 201 Si usted NO TIENE diabetes, por favor NO LLENE este últimos cuatro números de mi número telefónico son __ __ __ __. C. Marque todas las clases sobre diabetes

155

Obtención de perfiles teóricos de elementos metálicos con velocidades macroscópicas  

NASA Astrophysics Data System (ADS)

El propósito de este trabajo es poder establecer -a partir de la modelización de perfiles de distintas especies- patrones de comparación observacional que permitan caracterizar los fenómenos físicos que están presentes en las estructuras que se observan. Para ello se resuelven las ecuaciones de equilibrio de ionización para un determinado átomo y una atmósfera de parámetros determinados. A partir de ello se definen las poblaciones para los distintos grados de ionización. Considerando distintas configuraciones e intensidades de flujos de masa se deducen la función fuente, el espesor óptico y se calculan los perfiles de las distintas líneas. Se obtuvieron perfiles teóricos de líneas del CII, CIV y del OIV para flujos entrante, saliente y pasante. La forma del perfil, las intensidades relativas entre los distintos flujos y el corrimiento Doppler da cuenta de una caracterización teórica a partir de la cual se comparará con observaciones.

Cirigliano, D.; Costa, A.; Rovira, M.

156

RoboCon: Operator interface for robotic applications  

SciTech Connect

Carnegie Mellon U. and ORNL`s Robotics and Process Systems Division are developing a state-of-the-art robot operator control station (RoboCon) with standardized hardware and software control interfaces to be adaptable to a variety of remote and robotic equipment currently funded by DOE`s Office of Science & Technology Robotics Technology Development Program. The human operation and telerobotic and supervisory control of sophisticated and remote and robotic systems is a complex, tiring, and non-intuitive activity. Since decontamination & decommissioning, selective equipment removal, mixed waste operations, and in-tank cleanup are going to be a major future activity in DOE environmental restoration and waste management cleanup agenda, it seems necessary to utilize an operator control station and interface which maximizes operator comfort and productivity.

Schempf, H.; Warwick, J.; Fung, M.; Chemel, B.; Blackwell, M.

1996-12-31

157

Neogene sequence stratigraphy, Nam Con Son Basin, offshore Vietnam  

SciTech Connect

An integrated well log, biostratigraphic, and seismic stratigraphic study of Miocene to Recent deltaic sediments deposited in the Nam Con Son Basin offshore from southern Vietnam shows the influence of eustacy and tectonics on sequence development. Sediments consist of Oligocene non-marine rift-basin fill (Cau Formation), early to middle Miocene tide-dominated delta plain to delta front sediments (TB 1.5 to TB 2.5, Due and Thong Formations), and late Miocene to Recent marine shelf sediments (TB. 2.6 to TB 3.1 0, Mang Cau, Nam Con Son, and Bien Dong Formations). Eustacy controlled the timing of key surfaces and sand distribution in the tectonically-quiet early Miocene. Tectonic effects on middle to late Miocene sequence development consist of thick transgressive systems tracts due to basin-wide subsidence and transgression, sand distribution in the basin center, and carbonate sedimentation on isolated fault blocks within the basin. Third-order sequence boundaries (SB) are identified by spore peaks, sand stacking patterns, and channel incision. In the basin center, widespread shale beds with coal occur above sequence boundaries followed by transgressive sandstone units. These TST sandstones merge toward the basin margin where they lie on older HST sandstones. Maximum flooding surfaces (MFS) have abundant marine microfossils and mangrove pollen, a change in sand stacking pattern, and often a strong seismic reflection with downlap. Fourth-order genetic-type sequences are also interpreted. The MFS is the easiest marker to identify and correlate on well logs. Fourth-order SB occur within these genetic units but are harder to identify and correlate.

McMillen, K.J. [Beaver Creek Tech. Co., Mason, TX (United States); Do Van Luu; Lee, E.K.; Hong, S.S. [PEDCO, Ho Chi Minh City (Viet Nam)

1996-12-31

158

Neogene sequence stratigraphy, Nam Con Son Basin, offshore Vietnam  

SciTech Connect

An integrated well log, biostratigraphic, and seismic stratigraphic study of Miocene to Recent deltaic sediments deposited in the Nam Con Son Basin offshore from southern Vietnam shows the influence of eustacy and tectonics on sequence development. Sediments consist of Oligocene non-marine rift-basin fill (Cau Formation), early to middle Miocene tide-dominated delta plain to delta front sediments (TB 1.5 to TB 2.5, Due and Thong Formations), and late Miocene to Recent marine shelf sediments (TB. 2.6 to TB 3.1 0, Mang Cau, Nam Con Son, and Bien Dong Formations). Eustacy controlled the timing of key surfaces and sand distribution in the tectonically-quiet early Miocene. Tectonic effects on middle to late Miocene sequence development consist of thick transgressive systems tracts due to basin-wide subsidence and transgression, sand distribution in the basin center, and carbonate sedimentation on isolated fault blocks within the basin. Third-order sequence boundaries (SB) are identified by spore peaks, sand stacking patterns, and channel incision. In the basin center, widespread shale beds with coal occur above sequence boundaries followed by transgressive sandstone units. These TST sandstones merge toward the basin margin where they lie on older HST sandstones. Maximum flooding surfaces (MFS) have abundant marine microfossils and mangrove pollen, a change in sand stacking pattern, and often a strong seismic reflection with downlap. Fourth-order genetic-type sequences are also interpreted. The MFS is the easiest marker to identify and correlate on well logs. Fourth-order SB occur within these genetic units but are harder to identify and correlate.

McMillen, K.J. (Beaver Creek Tech. Co., Mason, TX (United States)); Do Van Luu; Lee, E.K.; Hong, S.S. (PEDCO, Ho Chi Minh City (Viet Nam))

1996-01-01

159

Gleevec disminuye la recidiva del cáncer en pacientes con tumor estromal gastrointestinal primario  

Cancer.gov

Los resultados preliminares de un estudio clínico grande aleatorio y controlado con placebo, en pacientes con tumor estromal gastrointestinal (GIST) primario, un tipo de tumor que por lo general se encuentra en el estómago o en el intestino delgado, demostraron que los pacientes a los que se administró mesilato de imatinib (Gleevec®) luego de la extirpación total de su tumor tuvieron una probabilidad significativamente menor de padecer una recidiva del cáncer en comparación con aquellos a los que no se administró imatinib.

160

Relaciones filogenéticas de Euptychiina (Lepidoptera: Satyrinae) con base en características morfológicas de los adultos.  

E-print Network

??Marín Uribe, Mario Alejandro (2011) Relaciones filogenéticas de Euptychiina (Lepidoptera: Satyrinae) con base en características morfológicas de los adultos. Maestría thesis, Universidad Nacional de Colombia.… (more)

Marín Uribe, Mario Alejandro

2011-01-01

161

Courses: Economics (ECON) Page 291Sonoma State University 2010-2011 Catalog eCOn 321 lABOr eCOnOMiCS (4)  

E-print Network

resources and the control of pollution. Topics include: energy, water, minerals, forests, air pollution, Africa, Asia and ex-socialist economies. Prerequisite: ECON 303 or 304 or consent of instructor. eCOn 404

Ravikumar, B.

162

Non Invasive Biomedical Analysis. Breath Networking Session at PittCon 2011, Atlanta, Georgia Non Invasive Biomedical Analysis. Breath Networking Session at PittCon 2011, Atlanta, Georgia  

Microsoft Academic Search

Background This was the second year that our breath colleagues organized a networking session at the Pittsburgh Conference and Exposition, or 'PittCon' (www.pittcon.org\\/). This time it was called 'Non Invasive Biomedical Analysis' to broaden the scope a bit, but the primary focus remained on exhaled breath diagnostics. As reported last year in the Journal of Breath Research, PittCon continues to

Joachim D. Pleil

2011-01-01

163

Pros, Cons, and Alternatives to Weight Based Cost Estimating  

NASA Technical Reports Server (NTRS)

Many cost estimating tools use weight as a major parameter in projecting the cost. This is often combined with modifying factors such as complexity, technical maturity of design, environment of operation, etc. to increase the fidelity of the estimate. For a set of conceptual designs, all meeting the same requirements, increased weight can be a major driver in increased cost. However, once a design is fixed, increased weight generally decreases cost, while decreased weight generally increases cost - and the relationship is not linear. Alternative approaches to estimating cost without using weight (except perhaps for materials costs) have been attempted to try to produce a tool usable throughout the design process - from concept studies through development. This paper will address the pros and cons of using weight based models for cost estimating, using liquid rocket engines as the example. It will then examine approaches that minimize the impct of weight based cost estimating. The Rocket Engine- Cost Model (RECM) is an attribute based model developed internally by Pratt & Whitney Rocketdyne for NASA. RECM will be presented primarily to show a successful method to use design and programmatic parameters instead of weight to estimate both design and development costs and production costs. An operations model developed by KSC, the Launch and Landing Effects Ground Operations model (LLEGO), will also be discussed.

Joyner, Claude R.; Lauriem, Jonathan R.; Levack, Daniel H.; Zapata, Edgar

2011-01-01

164

iCons class at UMass brings together students from all scientific disciplines  

E-print Network

iCons class at UMass brings together students from all scientific disciplines Published: Wednesday called iCons - #12;Integrated Concentration in Science - a program that allows students from all from all scientific disciplines to work together on real-world problems. Petsch is having the students

Auerbach, Scott M.

165

Accesibilidad para personas con debilidad visual Mac OS X Snow Leopard  

E-print Network

Accesibilidad para personas con debilidad visual Mac OS X Snow Leopard ASIC ­ 18 de noviembre de 2010 Pág. 1 de 25 GUÍA DE ACCESIBILIDAD PARA PERSONAS CON DEBILIDAD VISUAL EN ENTORNO MAC OS X SNOW LEOPARD Al igual que otros sistemas operativos, MAC OS X Snow Leopard ofrece algunas ayudas para que las

Fernández de Córdoba, Pedro

166

SURGIMIENTO Y DESARROLLO DE LA COMUNICACIÓN ORGANIZACIONAL Y SU RELACIÓN CON OTRAS CIENCIAS  

Microsoft Academic Search

El lenguaje nace como la conciencia, de la necesidad, de los apremios de relación con los demás hombres… La conciencia de la necesidad de entablar relaciones con los individuos circundantes es el comienzo de la conciencia de que el hombre vive, en general, dentro de una sociedad… La conciencia por tanto, es ya de antemano un producto social, y lo

Maria del Carmen Torres Alonso; José Alberto Alejo Becerra

2011-01-01

167

La salud en personas con discapacidad intelectual en España: estudio europeo POMONA-II  

PubMed Central

Introducción Estudios internacionales demuestran que existe un patrón diferenciado de salud y una disparidad en la atención sanitaria entre personas con discapacidad intelectual (DI) y población general. Objetivo Obtener datos sobre el estado de salud de las personas con DI y compararlos con datos de población general. Pacientes y métodos Se utilizó el conjunto de indicadores de salud P15 en una muestra de 111 sujetos con DI. Los datos de salud encontrados se compararon según el tipo de residencia de los sujetos y se utilizó la Encuesta Nacional de Salud 2006 para comparar estos datos con los de la población general. Resultados La muestra con DI presentó 25 veces más casos de epilepsia y el doble de obesidad. Un 20% presentó dolor bucal, y existió una alta presencia de problemas sensoriales, de movilidad y psicosis. Sin embargo, encontramos una baja presencia de patologías como la diabetes, la hipertensión, la osteoartritis y la osteoporosis. También presentaron una menor participación en programas de prevención y promoción de la salud, un mayor número de ingresos hospitalarios y un uso menor de los servicios de urgencia. Conclusiones El patrón de salud de las personas con DI difiere del de la población general, y éstas realizan un uso distinto de los servicios sanitarios. Es importante el desarrollo de programas de promoción de salud y de formación profesional específicamente diseñados para la atención de personas con DI, así como la implementación de encuestas de salud que incluyan datos sobre esta población. PMID:21948011

Martínez-Leal, Rafael; Salvador-Carulla, Luis; Gutiérrez-Colosía, Mencía Ruiz; Nadal, Margarida; Novell-Alsina, Ramón; Martorell, Almudena; González-Gordón, Rodrigo G.; Mérida-Gutiérrez, M. Reyes; Ángel, Silvia; Milagrosa-Tejonero, Luisa; Rodríguez, Alicia; García-Gutiérrez, Juan C.; Pérez-Vicente, Amado; García-Ibáñez, José; Aguilera-Inés, Francisco

2011-01-01

168

Elizabeth A.Johnson y Kefyn M.Catley con ilustraciones de Patricia J. Wynne  

E-print Network

Vidaen la Hojarasca La Elizabeth A.Johnson y Kefyn M.Catley con ilustraciones de Patricia J. Wynne Elizabeth A. Johnson y Kefyn M. Catley con ilustraciones de Patricia J. Wynne Ellen V. Futter, Presidente personal y voluntarios del CBC Escrito por: Elizabeth A. Johnson (Center for Biodiversity and Conservation

169

Per: Chirapaq celebra 25 aos con un foro sobre "Derechos de los Pueblos Indgenas"  

E-print Network

Perú: Chirapaq celebra 25 años con un foro sobre "Derechos de los Pueblos Indígenas celebrará su 25 aniversario con el foro público internacional: "Derechos de los Pueblos Indígenas: Avances y la Nación Cree, ex parlamentario y miembro del Mecanismo de Expertos sobre los Derechos de los

Islas, León

170

Context reasoning is the process of drawing con-clusions from existing context information, and is  

E-print Network

Abstract Context reasoning is the process of drawing con- clusions from existing context information, and is considered crucial to geospatial interoperability. However, such reasoning still remains and mod- eling the external quality (fitness-for-use) of con- text information is important for reasoning

171

Cursos Oficiales ETSII-URJC Obtn tu Diploma con los nuevos cursos de  

E-print Network

REST con Spring MVC MongoDB Spring Data Testing Servicios cloud computing: APIs REST para aplicaciones web y móviles con Spring y MongoDB Del 20 de marzo al 4 de abril, de 13 a 15h Duración: 20 horas

Rey Juan Carlos, Universidad

172

Almost-Flat Line Con gurations Department of Industrial Sciences and Technology  

E-print Network

Communications, Robot Kinematics, e.a.). In order to classify the con#12;gurations of n lines in real (a). This is called the planar layout of the con#12;gurations. So, in a planar layout one line can \\cross over" or \\cross under" or intersect another line. The char- acterization of the possible planar layouts of n lines

Penne, Rudi

173

Persisten las diferencias de cáncer de seno en hispanas con el mismo acceso a la atención médica  

Cancer.gov

Con el mismo acceso a servicios médicos, persisten las diferencias en cuanto al tamaño, el estadio y el grado del cáncer de seno en las mujeres hispanas en comparación con las mujeres blancas no hispanas.

174

Global Environmental Change 11 (2001) 69}78 Sahel pastoralists: opportunism, struggle, con#ict and negotiation.  

E-print Network

Global Environmental Change 11 (2001) 69}78 Sahel pastoralists: opportunism, struggle, con#ict in to insure access to resources; to the nature of con#icts and co-operation between ethnic groups and pasture, culminating in present-day tensions and con#ict between pastoral groups. State development e

Batterbury, Simon

175

Determination of composition in stoichiometric Co-N ultrathin films by nitrogen plasma sputtering  

SciTech Connect

This work utilizes low-energy sputtering to incorporate the generated nitrogen plasma into an epitaxial 1.4 nm Co film on the surface of a ZnO(002) substrate. In this method, ultrathin Co-N amorphous films were formed. Interestingly, Co is key to the formation of Co-N films. Without the deposition of Co on the ZnO(002), nitride films cannot be formed. Observations of the surface composition of the Co-N films after the firing of a N{sup +} ion beam onto it demonstrated that the surface concentration of Co reduced at the same rate as the reduction in the concentration of N upon successive sputtering. Theoretical calculations based on the Auger peak-to-peak amplitudes established that the composition of the amorphous Co-N thin films may be Co{sub 3}N{sub 2}.

Su, C. W.; Huang, M. S.; Chang, Y. C.; Tsai, T. H. [Department of Applied Physics, National Chiayi University, 300 Syuefu Rd., Chiayi 60004, Taiwan (China); Lee, Y. H.; Lee, J. C. [Department of Physics, National Cheng Kung University, 1 University Rd., Tainan 70101, Taiwan (China)

2009-02-01

176

El tratamiento con cloro es un mtodo para desinfectar un pozo de agua. Se recomien-  

E-print Network

exceso de lluvia entran en el pozo. Si el agua subterránea constituye en sí la fuente de bacterias, elEl tratamiento con cloro es un método para desinfectar un pozo de agua. Se recomien- da cuando un sistema de agua está contam- inado con bacterias. La contaminación puede ocurrir en la instalación del

177

EyeCon -- a motion sensing tool for creating interactive dance, music and video projections  

Microsoft Academic Search

EyeCon is a video-based motion sensing system which allows performers to generate or control music and projected images through their movements and gestures in space. It was developed Frieder Weiß as an application- driven project of the Palindrome inter-media performance group and is thus more a tool for artists than for researchers. EyeCon does, however, allow motion sensing according to

Robert Wechsler; Peter Dowling

178

Quimioterapia de alta dosis prolonga en forma significativa la supervivencia en pacientes con leucemia mieloide aguda  

Cancer.gov

Los resultados preliminares de un estudio clínico grande con asignación al azar de pacientes de 16 a 60 años de edad con leucemia mieloide aguda (LMA), un cáncer de la sangre y de la médula ósea, que no había sido tratada anteriormente, muestran que los pacientes que recibieron una alta dosis de daunorrubicina, un fármaco de quimioterapia disponible comercialmente, durante la terapia inicial vivieron más que los pacientes que recibieron una dosis normal del mismo fármaco.

179

NSF funds iCons and HCC interdisciplinary renewable energy labs The campus' Integrated Concentration in Science (iCons) program and  

E-print Network

NSF funds iCons and HCC interdisciplinary renewable energy labs The campus' Integrated in integrative education with an emphasis on current societal problems to create the renewable energy laboratory-of-the- art renewable energy laboratory courses at both institutions thanks to $250,000 in National Science

Auerbach, Scott M.

180

A Review of "Becoming Neapolitan. Citizen Culture in Baroque Naples" by John A. Marino  

E-print Network

(in October 1571) or the great eruption of Mount Vesuvius (in December 1631). There was a significant development in the nature of festivities in that the Church after Trent, and the viceroys tended to exert control over earlier more popular...

Litchfield, R. Burr

2011-01-01

181

REPRESENTING PHYSICAL AND DESIGN KNOWLEDGE IN INNOVATIVE DESIGN NIKITAS MARINOS SGOUROS  

E-print Network

Physical Knowledge 14 2.3 .1 Representations 14 2.3 .2 Reasoning Methods 15 2 .4 Design Knowledge 20 2.4 .1 Heuristics 20 2.4 .2 Representing Heuristics 23 2.4 .3 Strategies 25 vi #12;2 .4.4 Configuration Synthesis helpful comments. · The NASA Johnson Space Center and the NASA Langley Research Center for supporting

Forbus, Kenneth D.

182

The "0", is it an obstacle? Di Leonardo M.V., Marino T., Spagnolo F.1  

E-print Network

, like Bruosseau say, "obstacles" to learn the mathematics. Surely that obstacles could be defined experimental phase relating to a preparation of a pre-test (see Appendice 2) 1.1 Why the "zero"? Does it exist and acquaintance process transforming something that in an inferior level is purely operational in something

Spagnolo, Filippo

183

Virulence, Speciation and Antibiotic Susceptibility of Ocular Coagualase Negative Staphylococci (CoNS)  

PubMed Central

Background: Coagulase negative Staphylococci (CoNS) are common inhabitants of human skin and mucous membranes. With the emergence of these organisms as prominent pathogens in patients with ocular infections, investigation has intensified in an effort to identify important virulence factors and to inform new approaches to treatment and prevention. Aim: To isolate CoNS from ocular specimens; to study the possible virulence factors; speciation of coagulase negative staphylococci (CoNS) which were isolated from ocular complications; antibiotic susceptibility testing of ocular CoNS. Materials and Methods: The specimens were collected from the target patients who attended the Microbiology Laboratory of a tertiary care eye hospital in Coimbatore, Tamilnadu state, India. The isolates were subjected to tube and slide coagulase tests for the identification of CoNS. All the isolates were subjected to screening for lipase and protease activities. Screening for other virulence factors viz., slime production on Congo red agar medium and haemagglutination assay with use of 96-well microtitre plates. These isolates were identified upto species level by performing biochemical tests such as phosphatase test, arginine test, maltose and trehalose fermentation tests and novobiocin sensitivity test. The isolates were subjected to antibiotic susceptibility studies, based on the revised standards of Clinical and Laboratory Standards Institutes (CLSI). Results: During the one year of study, among the total 260 individuals who were screened, 100 isolates of CoNS were obtained. Lipolytic activity was seen in all the isolates, whereas 38 isolates showed a positive result for protease. A total of 63 isolates showed slime production. Of 100 isolates, 30 isolates were analyzed for haemagglutination, where 4 isolates showed the capacity to agglutinate the erythrocytes. The results of the biochemical analysis revealed that of the 100 isolates of CoNS, 43% were Staphylococcus epidermidis. The other isolates were identified as S. xylosus (n=8), S. captis (n=16), S. haemolyticus (n=10), S. saccharolyticus (n=2), S. hominis (n=5), S. saprophyticus (n=6) and S. intermedius (n=1). On the other hand, 9 isolates were not identified. In the antibiotic susceptibility analysis, it was found that most of the isolates were sensitive to vancomycin, amikacin and linczolid and resistant to cefatoxime, oxacillin, bacitracin and nalidixic acid. Conclusion: S. epidermidis was found to be predominant in causing the ocular complications. Slime production, heamagglutination, protease and lipase activities could be the putative virulence factors of CoNS. Antibiotic susceptibility patterns of CoNS against antibacterial agents revealed maximum resistance to beta lactam groups, and the resistance was found to be higher to oxacillin, and lowest to vancomycin. PMID:24995181

Priya, Ravindran; Mythili, Arumugam; Singh, Yendremban Randhir Babu; Sreekumar, Haridas; Manikandan, Palanisamy; Panneerselvam, Kanesan

2014-01-01

184

Structural basis of ConM binding with resveratrol, an anti-inflammatory and antioxidant polyphenol.  

PubMed

Resveratrol can also inhibit the activation of proinflammatory mediators and cytokines at the early gene expression stage. It is well known that lectins are sugar-binding proteins that act as both pro- and anti-inflammatory molecules. Thus, the objective of this work was to verify the binding of a polyphenol compound with a lectin of Canavalia maritima (ConM) based on their ability to inhibit pro-inflammatory processes. To accomplish this, ConM was purified and crystallized, and resveratrol was soaked at 5mM for 2h of incubation. The crystal belongs to the monoclinic space group C2, the final refinement resulted in an Rfactor of 16.0% and an Rfree of 25.5%. Resveratrol binds in the rigid ?-sheet through H-bonds and hydrophobic interaction with amino acids that compose the fifth and sixth ?-strands of the rigid ?-sheet of ConM. The ConM and resveratrol inhibited DPPH oxidation, showing synergic activity with the most effective ratio of 2:3 and carbohydrate binding site is not directly related to antioxidant activity. It is the interaction between ConM and resveratrol that indicates the synergism of these two molecules in acting as free radicals scavengers and in reducing the inflammatory process through the inhibition of many pro-inflammatory events. PMID:25192853

Rocha, Bruno A M; Teixeira, Claudener S; Silva-Filho, José C; Nóbrega, Raphael B; Alencar, Daniel B; Nascimento, Kyria S; Freire, Valder N; Gottfried, Carmem J S; Nagano, Celso S; Sampaio, Alexandre H; Saker-Sampaio, Silvana; Cavada, Benildo S; Delatorre, Plínio

2015-01-01

185

ConSole: using modularity of Contact maps to locate Solenoid domains in protein structures  

PubMed Central

Background Periodic proteins, characterized by the presence of multiple repeats of short motifs, form an interesting and seldom-studied group. Due to often extreme divergence in sequence, detection and analysis of such motifs is performed more reliably on the structural level. Yet, few algorithms have been developed for the detection and analysis of structures of periodic proteins. Results ConSole recognizes modularity in protein contact maps, allowing for precise identification of repeats in solenoid protein structures, an important subgroup of periodic proteins. Tests on benchmarks show that ConSole has higher recognition accuracy as compared to Raphael, the only other publicly available solenoid structure detection tool. As a next step of ConSole analysis, we show how detection of solenoid repeats in structures can be used to improve sequence recognition of these motifs and to detect subtle irregularities of repeat lengths in three solenoid protein families. Conclusions The ConSole algorithm provides a fast and accurate tool to recognize solenoid protein structures as a whole and to identify individual solenoid repeat units from a structure. ConSole is available as a web-based, interactive server and is available for download at http://console.sanfordburnham.org. PMID:24766872

2014-01-01

186

ConA-based glucose sensing using the long-lifetime azadioxatriangulenium fluorophore  

NASA Astrophysics Data System (ADS)

Fluorescent glucose sensing technologies have been identified as possible alternatives to current continuous glucose monitoring approaches. We have recently introduced a new, smart fluorescent ligand to overcome the traditional problems of ConA-based glucose sensors. For this assay to be translated into a continuous glucose monitoring device where both components are free in solution, the molecular weight of the smart fluorescent ligand must be increased. We have identified ovalbumin as a naturally-occurring glycoprotein that could serve as the core-component of a 2nd generation smart fluorescent ligand. It has a single asparagine residue that is capable of displaying an N-linked glycan and a similar isoelectric point to ConA. Thus, binding between ConA and ovalbumin can potentially be monovalent and sugar specific. This work is the preliminary implementation of fluorescently-labeled ovalbumin in the ConA-based assay. We conjugate the red-emitting, long-lifetime azadioxatriangulenium (ADOTA+) dye to ovalbumin, as ADOTA have many advantageous properties to track the equilibrium binding of the assay. The ADOTA-labeled ovalbumin is paired with Alexa Fluor 647-labeled ConA to create a Förster Resonance Energy Transfer (FRET) assay that is glucose dependent. The assay responds across the physiologically relevant glucose range (0-500 mg/dL) with increasing intensity from the ADOTA-ovalbumin, showing that the strategy may allow for the translation of the smart fluorescent ligand concept into a continuous glucose monitoring device.

Cummins, Brian; Simpson, Jonathan; Gryczynski, Zygmunt; Sørensen, Thomas Just; Laursen, Bo W.; Graham, Duncan; Birch, David; Coté, Gerard

2014-02-01

187

Estudios estructurales sobre entidades tiosemicarbazonacobre(II) y su interacción con polioxometalatos y biomoléculas: síntesis, estabilidad y propiedades magnéticas.  

E-print Network

??Estudios estructurales sobre entidades tiosemicarbazonacobre(II) y su interacción con polioxometalatos y biomoléculas. Síntesis, estabilidad y propiedades magnéticas? El presente Trabajo ahonda en la síntesis y… (more)

Gil García, Rubén

2012-01-01

188

Estrategia de aula para alcanzar aprendizajes significativos y desarrollar habilidades de pensamiento científico en relación con la meiosis.  

E-print Network

??Villada Salazar, Claudia Patricia (2011) Estrategia de aula para alcanzar aprendizajes significativos y desarrollar habilidades de pensamiento científico en relación con la meiosis. Maestría thesis,… (more)

Villada Salazar, Claudia Patricia

2011-01-01

189

Un estudio financiado por los Institutos Nacionales de la Salud (NIH) muestra reducción en la mortalidad entre hombres con cáncer de próstata en grado intermedio:  

Cancer.gov

Terapia hormonal por corto tiempo administrada en combinación con radioterapia a hombres con cáncer de próstata en estadio inicial aumentó sus posibilidades de vivir más en comparación con tratamiento de radioterapia sola, según un estudio clínico patrocinado por el NCI. Los beneficios del tratamiento combinado se limitaron principalmente a pacientes con enfermedad de riesgo intermedio y no se observaron en hombres con cáncer de próstata de riesgo bajo, indican los investigadores.

190

Zoning administrators and others con-cerned with airport land use will soon  

E-print Network

Zoning administrators and others con- cerned with airport land use will soon have help when it comes to making decisions that affect their airports. The recently completed Airport Land Use zoning stan- dards, local ordinances, and land use. The manual was developed by the Minnesota Department

Minnesota, University of

191

Costo de capital con costo del patrimonio apalancado como el riesgo de los escudos fiscales  

Microsoft Academic Search

Se presenta la derivación de costo de capital bajo la premisa del ahorro de impuestos de riesgo descuento con el costo de capital apalancado. Se demuestra que la formulación es coherente y se deriva de los principios financieros básicos. Esta formulación es válida para los flujos de caja finitos y perpetuidades sin crecimiento. Además, se puede calcular sin la circularidad

Joseph Tham; Ignacio Velez Pareja

2010-01-01

192

Timectomía por videotoracoscopia asistida con bloqueo anestésico paravertebral bilateral en pacientes miasténicos  

Microsoft Academic Search

Summary Thymectomy continues to be the treatment of choice for certain patients with myasthenia gravis. As surgical techniques have developed, anesthesiologists have con- sidered the need to adapt anesthetic techniques to improve care of patients undergoing this procedure. We describe the anesthetic management of 2 patients under- going thymectomy performed with a bilateral thoracos- copic approach. Because it is best

J. L. López-Berlanga; I. Garutti; E. Martínez-Campos; P. Piñeiro; D. Salvatierra

193

Science for conServation 293 Loss of genetic diversity and  

E-print Network

Science for conServation 293 Loss of genetic diversity and inbreeding in New Zealand's threatened of Conservation. This paper may be cited as: Jamieson, I.G. 2009: Loss of genetic diversity and inbreeding in New bird species #12;Loss of genetic diversity and inbreeding in New Zealand's threatened bird species Ian

Jamieson, Ian

194

Integrated Concentration in Science, 2012 High Fructose Corn Syrup a mini iCons case study  

E-print Network

© Integrated Concentration in Science, 2012 High Fructose Corn Syrup­ a mini iCons case study researchers find that high fructose corn syrup prompts considerably more weight gain. http://www.princeton.edu/main/news/archive/S26/91/22K07/ The Atlantic, Aug 13, 2012 ­ Study: High fructose corn syrup no worse than `real' sugar

Auerbach, Scott M.

195

Safety and Toxicity Evaluation of GonaCon ™ Immunocontraceptive Vaccine in White-Tailed Deer  

Microsoft Academic Search

GonaCon ™ Immunocontraceptive Vaccine targets the reproductive hormone gonadotropin releasing hormone (GnRH) secreted by the hypothalamus of the brain. Antibodies produced in response to the vaccine inactivate endogenous GnRH, which in turn eliminates stimulation of the pituitary gland and gonads in males or females. The resulting \\

Gary Killian; Donald Wagner; Richard Engeman; Lowell Miller

196

On the Detection of Con icts in Diagnostic Bayesian Networks Using Abstraction  

E-print Network

On the Detection of Con icts in Diagnostic Bayesian Networks Using Abstraction Young-Gyun Kim Bayesian net- work (the base model) and constructs, with- out assistance, a bipartite network to be used and imple- mented. 1 INTRODUCTION Developing a diagnostic expert system that uses a Bayesian network

Valtorta, Marco

197

CecileBernard La escasez de alimentos que. con distinto gr&o. afectz a  

E-print Network

-,- .e CI' I CecileBernard La escasez de alimentos que. con distinto gr&o. afectz a la mayoría de respecta al abasto de alimentos, se reactiva una institución creada en 1965, la CONASUPO (CompaFh Na alimentos principales (tortillas, enva- sado de la leche), monopoliode la importación de granos (M. Durand

Paris-Sud XI, Université de

198

La fecha ltima en que el alimento se debe La mayora de los alimentos pueden con-  

E-print Network

La fecha última en que el alimento se debe vender. ****************************************** La mayoría de los alimentos pueden con- sumirse después de esta fecha, SI han sido manejados y guardados bolsas). ****************************************** No compre alimentos después de la fecha "véndase

199

Una entrevista con Inés Margarita Stranger (Chile) y sus personajes femeninos  

E-print Network

FALL 1996 89 Una entrevista con Inés Margarita Stranger (Chile) y sus personajes femeninos Pedro Bravo-Elizondo A la fecha, su vida contempla un título como teatrista por la Universidad Católica de Chile en la cual es profesora en la Escuela de...

Bravo-Elizondo, Pedro

1996-10-01

200

Onion Routing Access Con gurations Paul F. Syverson, Michael G. Reed, and David M. Goldschlag  

E-print Network

Onion Routing Access Con gurations Paul F. Syverson, Michael G. Reed, and David M. Goldschlag Naval Research Laboratory Abstract Onion Routing is an infrastructure for private com- munication over and tra c analysis. Thus it hides not only the data being sent, but who is talking to whom. Onion Routing

201

Impactos del Huracn Isaac en la calidad del agua en Luisiana con MODIS 250m  

E-print Network

lluvias. Por tal razón se quiere estudiar la calidad del agua en el delta del río Mississippi antes1 Impactos del Huracán Isaac en la calidad del agua en Luisiana con MODIS 250m Thais J. Alicea imágenes en ENVI. Palabras clave: Calidad del agua, ENVI, Isaac, Luisiana, MODIS

Gilbes, Fernando

202

Although most Minnesota airports do not have much concrete pavement, the con-  

E-print Network

Although most Minnesota airports do not have much concrete pavement, the con- crete they do have are generally constructed out of concrete that is much thicker. Maintaining any section of pavement, regardless of its size, is important for pre- serving its condition and optimizing pave- ment life. Pavement

Minnesota, University of

203

Iron formations are typically thinly bed-ded or laminated sedimentary rocks con-  

E-print Network

222 ABSTRACT Iron formations are typically thinly bed- ded or laminated sedimentary rocks con- taining 15% or more of iron and a large pro- portion of silica (commonly >40%). In the ca. 2590­2460 Ma Campbellrand-Kuruman Complex, Transvaal Supergroup, South Africa, iron formation occurs as a sediment- starved

Fischer, Woodward

204

ANALISI DEL DANNEGGIAMENTO SU COMPONENTI IN MATERIALE COMPOSITO CON TECNICA TERMOELASTICA  

Microsoft Academic Search

Sommario Il largo e crescente utilizzo di materiali compositi in applicazioni ingegneristiche di estrema importanza, quali ad esempio quelle aerospaziali, ha posto l'attenzione su tecniche, come quella termoelastica, che consentono una valutazione delle sollecitazioni rapida e a campo intero. Parallelamente risulta di estremo interesse la valutazione dell'integrità strutturale del componente in esame mediante controlli non distruttivi come quelli con ultrasuoni

U. Galietti; C. Pappalettere

2009-01-01

205

The Value of Literacy Beyond Reading: Empowering Adult Women Through Knowledge and Con...dence  

E-print Network

The Value of Literacy Beyond Reading: Empowering Adult Women Through Knowledge and Con funded by the Social Science Research Council of Canada. 1 #12;Abstract Adult female literacy around the world to institute large scale adult literacy programs. However, evidence on the e

Bandyopadhyay, Antar

206

La Universidad de Alicante coordina un nuevo proyecto Erasmus Mundus con 21 universidades  

E-print Network

entre las universidades europeas que ha obtenido financiación externa para la movilidad e intercambio de, gracias a un nuevo proyecto denominado "Proyecto de Movilidad Transeuropea sobre la Educación para el Arquitectura. El proyecto contará con un presupuesto de 3.508.975 de euros y ofrecerá 212 becas de movilidad

Escolano, Francisco

207

Hand Detection on Sign Language Videos Zhong Zhang, Christopher Conly, and Vassilis Athitsos  

E-print Network

Hand Detection on Sign Language Videos Zhong Zhang, Christopher Conly, and Vassilis Athitsos.zhang@mavs.uta.edu, cconly@uta.edu, athitsos@uta.edu ABSTRACT For gesture and sign language recognition, hand shape and hand an efficient and reliable hand detector is therefore an important step in recognizing signs and gestures

Athitsos, Vassilis

208

Con il patrocinio di / Sponsored by IRCCS, Santa Lucia Foundation, Roma  

E-print Network

Neuroscience and society Marzo / March 11-13, 2013, Rome Cognitive and Social Neuroscience Laboratory da un Neuroscienze Sociali e Cognitive / Speakers from Social and Cognitive Neuroscience Lab: o Enea Francesco Pavone dopo stimolazione del volto in persone con lesione al midollo spinale" - "The rubber hand illusion

Di Pillo, Gianni

209

LA PSICOLOGÍA ORGANIZACIONAL, VÍNCULO CON EL PROCESO DE PREVENCIÓN SOCIAL EN EL MUNICIPIO JESUS MENÉNDEZ  

Microsoft Academic Search

Con el objetivo de mejorar los resultados en la labor de prevención y atención social en el municipio Jesús Menéndez, contribuir al perfeccionamiento de la gestión institucional de las organizaciones laborales en el territorio y fortalecer la pertinencia de la carrera de Licenciatura en Psicología de la Sede Universitaria Municipal Jesús Menéndez, se adecuan los programas de estudio de la

Aliek Méndez Bordón; Marlene Goytizolo Andreus

2012-01-01

210

Abstract A model of "distributed cognition" is con-trasted with the "mental representation" model exempli-  

E-print Network

Abstract A model of "distributed cognition" is con- trasted with the "mental representation" model exempli- fied by Tomasello and Call's Primate Cognition. Rather than using behavior as a basis interactions as, themselves, directly observable cognitive events. Similar to a Vygotskian ap- proach

Kirsh, David

211

Mul$-scale Demand-Side Management for Con$nuous Power-intensive Processes  

E-print Network

and uncertainty in prices · Timing and produc(on quan((es (DR)* · Inventory management inventory facilitate performing Demand-side Management (DSM) at air separa$on plants1 Mul$-scale Demand-Side Management for Con$nuous Power-intensive Processes

Grossmann, Ignacio E.

212

Salud con Sabor Latino: a culturally sensitive obesity prevention curriculum in an underserved Latino community  

Microsoft Academic Search

Salud con Sabor Latino is a culturally sensitive obesity prevention curriculum that incorporates the traditions and values of the Latino community and family. The 4-week curriculum meets twice a week and includes an education and cooking component. Key components of the curriculum are portion size, reading food labels, taking small steps, eating a variety of foods, and the importance of

Christina Araiza; Maria Valenzuela; Bonnie Gance-Cleveland

2012-01-01

213

Formulación de alimentos para celíacos con base en mezclas de harinas de quínoa, cereales y almidones  

Microsoft Academic Search

RESUMEN. Se formularon alimentos sin gluten para celíacos en base a mezclas de harina de quínoa (Chenopodium quinoa), arroz y maíz con almidones. Para la formulación de estos alimentos se usó la herramienta informática (ALIM V1.0) desarrollada por los auto- res. Se obtuvieron panqueques, scones, prepizza y pan, los cuales fueron evaluados en composición química (proteínas, grasas, ceni- zas, fibras,

Valeria Del Castillo; Gerardo Lescano; Margarita Armada

214

DIGITAL.CSIC: "Catalogacin con Dublin Core, gestin de derechos de  

E-print Network

DIGITAL.CSIC: "Catalogación con Dublin Core, gestión de derechos de autor y permisos de editores;Copyright y el acceso abierto #12;¿De qué estamos hablando? · Derechos de autor: conjunto de normas y principios que regulan los derechos morales y patrimoniales que la ley concede a los autores por el solo

215

Accordo con il Teatro Nuovo di Milano Stagione 2009/10 Destinatari  

E-print Network

dell'Università degli Studi di Milano con tesserino UNIMI e documento d'identità, sino ad esaurimento diritto, ad un biglietto ridotto del 50% sul biglietto intero del settore poltrona, per il titolare ed un incontra l'anima del Gospel. da mar. 29 dicembre 2009 a Loretta Goggi S.P.A. mer. 06 gennaio

De Cindio, Fiorella

216

Medidas antropométricas como predictores del comportamiento lipídico sérico en adolescentes con síndrome de Down  

Microsoft Academic Search

Current findings suggest that more attention needs to be gi- ven to the increase in body mass being achieved by disabled populations in general and individuals with mental retarda- tion in particular, to minimize long-term negative health con- sequences. Given that physical activity programs have been reported as one of the most effective ways of improving the health of individuals

Francisco Javier Ordóñez-Munoz; Manuel Rosety-Rodríguez; Jesús María Rosety-Rodríguez; Manuel Rosety-Plaza

217

Pros and Cons of Teaching Reading to Four- and Five-Year-Olds.  

ERIC Educational Resources Information Center

There are many pros and cons to the recent trend of early reading. The opponents fear that too much emphasis on early reading may lead to a less rounded development of the child; they agree on providing the child with richer and more varied experiences to insure reading readiness. The advocates believe that today's children have already had more…

Ollila, Lloyd O.

218

Annotating Web Images using NOVA: NOn-conVex group College of Computer Science,  

E-print Network

Annotating Web Images using NOVA: NOn-conVex group spArsity Fei Wu College of Computer Science, NOVA is the first to introduce non-convex penalty for group selection in high-dimensional heterogeneous it uses non-convex penalty, it achieves the consistency. We demonstrate the superior performance of NOVA

Rui, Yong

219

Violación del Principio de Equivalencia en Teorías con Dilatón de Cuerdas  

Microsoft Academic Search

Se estudian las violaciones al Principio de Equivalencia en Teorías con Dilatón de Cuerdas. En estos modelos, algunas de las constantes fundamentales dependen del espacio y del tiempo. Se muestra que los experimentos de caída libre no tienen aún precisión como para poner límites a los parámetros de la teoría.

S. J. Landau; P. D. Sisterna; H. Vucetich

2003-01-01

220

Non Invasive Biomedical Analysis - Breath Networking Session at PittCon 2011, Atlanta, Georgia  

EPA Science Inventory

This was the second year that our breath colleagues organized a networking session at the Pittsburgh Conference and Exposition or ''PittCon'' (http://www.pincon.org/).This time it was called "Non-invasive Biomedical Analysis" to broaden the scope a bit, but the primary focus rema...

221

conStruction MAnAgeMent College of Rural and Community Development  

E-print Network

The construction management program meets growing needs in the con- struction industry by training entry to the largest of skyscrapers and industrial projects; and on rural roads to major highways. Construction principles of busi- ness and know about the technical aspects of the construction industry. Graduates

Hartman, Chris

222

DESign AnD conStruction College of Engineering and Mines  

E-print Network

in the construction industry. The program was designed in collaboration with construction industry em- ployers and continues to engage industry as a partner in the program. Engineers and other construction professionalsDESign AnD conStruction MAnAgEMEnt College of Engineering and Mines Department of Civil

Hartman, Chris

223

INTRODUCTION Recent studies have demonstrated that resting state fMRI (rs-fMRI) con-  

E-print Network

INTRODUCTION Recent studies have demonstrated that resting state fMRI (rs-fMRI) con- nectivity to the need for: (1) a training dataset, (2) a-priori information about informative connections, and a (3 PROCESSING AT THE SINGLE SUBJECT LEVEL USING WHOLE-BRAIN FMRI CONNECTIVITY METHODS ( Experimental Paradigm

Bandettini, Peter A.

224

Enrichment of Glycoproteins using Nano-scale Chelating Con A Monolithic Capillary Chromatography  

PubMed Central

Immobilized lectin chromatography can be employed for glycoprotein enrichment, but commonly used columns have limitations of yield and resolution. In order to improve efficiency and to make the technique applicable to minimal sample material, we have developed a nano-scale chelating Concanavalin A (Con A) monolithic capillary prepared using GMA-EDMA (glycidyl methacrylate–co-ethylene dimethacrylate) as polymeric support. Con A was immobilized on Cu(II)-charged iminodiacetic acid (IDA) regenerable sorbents by forming a IDA:Cu(II):Con A sandwich affinity structure that has high column capacity as well as stability. When compared with conventional Con A lectin chromatography, the monolithic capillary enabled the better reproducible detection of over double the number of unique N-glycoproteins in human urine samples. Utility for analysis of minimal biological samples was confirmed by the successful elucidation of glycoprotein profiles in mouse urine samples at the microliter scale. The improved efficiency of the nano-scale monolithic capillary will impact the analysis of glycoproteins in complex biological samples, especially where only limited material may be available. PMID:19366252

Feng, Shun; Yang, Na; Pennathur, Subramaniam; Goodison, Steve; Lubman, David M.

2009-01-01

225

Adsornftl 8~f^Ll* ORNL/CON-155 O173IS1o COp  

E-print Network

of Stirling Engine Thermodynamics N. C. J. Chen F. P. Griffin C. D. West OPERATED BY TAHP *MARTIN MARIETTA Government or any agency thereof. #12;ORNL/CON-155 LINEAR HARMONIC ANALYSIS OF STIRLING ENGINE THERMODYNAMICS ................... 8 2.3 Integrated Energy Equations ......................... 11 2.4 Engine Performance Parameters

Oak Ridge National Laboratory

226

Oro-facial injuries in Central American and Caribbean sports games: a 20-year experience.  

PubMed

Dental services in sports competitions in the Games sponsored by the International Olympic Committee are mandatory. In every Central American, Pan American and Olympic Summer Games, as well as Winter Games, the Organizing Committee has to take all the necessary measures to assure dental services to all competitors. In all Olympic villages, as part of the medical services, a dental clinic is set up to treat any dental emergency that may arise during the Games. Almost every participating country in the Games has its own medical team and some may include a dentist. The major responsibilities of the team dentist as a member of the national sports delegation include: (i) education of the sports delegation about different oral and dental diseases and the illustration of possible problems that athletes or other personnel may encounter during the Games, (ii) adequate training and management of orofacial trauma during the competition, (iii) knowledge about the rules and regulations of the specific sport that the dentist is working, (iv) understanding of the anti-doping control regulations and procedures, (v) necessary skills to fabricate a custom-made and properly fitted mouth guard to all participants in contact or collision sports of the delegation. This study illustrates the dental services and occurrence of orofacial injury at the Central American and Caribbean Sports Games of the Puerto Rican Delegation for the past 20 years. A total of 2107 participants made up the six different delegations at these Games. Of these 279 or 13.2% were seen for different dental conditions. The incidence of acute or emergency orofacial conditions was 18 cases or 6% of the total participants. The most frequent injury was lip contusion with four cases and the sport that experienced more injuries was basketball with three cases. PMID:15876321

Amy, Enrique

2005-06-01

227

Laser therapy in the management of dental and oro-facial trauma  

NASA Astrophysics Data System (ADS)

This is a clinical presentation demonstrating the efficacy of laser therapy in the treatment of patients presenting with trauma to both the hard and soft tissue in the orofacial region. The use of laser therapy aids the management of these cases where the patients often present with anxiety and a low pain threshold. The outcomes in these cases indicate good patient acceptance of the treatment, enhanced repair and tissue response suggesting that this form of treatment can be indicated for these patients. A combination of hard and soft lasers are used for the comprehensive dental management and treatment of these cases. The lasers used are a 810nm diode and an Er.CrYSGG.

Darbar, Arun A.

2007-02-01

228

Cell signaling mechanisms of oro-gustatory detection of dietary fat: advances and challenges.  

PubMed

CD36 and two G-protein coupled receptors (GPCR), i.e., GPR120 and GPR40, have been implicated in the gustatory perception of dietary fats in rodents. These glycoproteins are coupled to increases in free intracellular Ca²? concentrations, [Ca²?](i), during their activation by dietary long-chain fatty acids (LCFA). The transient receptor potential type M5 (TRPM5) channel, activated by [Ca²?](i), participates in downstream signaling in taste bud cells (TBC). The mice, knocked-out for expression of CD36, GPR120, GPR40 or TRPM5 have a reduced spontaneous preference for fat. The delayed rectifying K? (DRK) channels believed to lie downstream of these receptors are also important players in fat taste transduction. The trigeminal neurons by triggering increases in [Ca²?](i) may influence the taste signal to afferent nerve fibers. Why are there so many taste receptor candidates for one taste modality? We discuss the recent advances on the role of CD36, GPR120, GPR40, TRPM5 and DRK channels, in signal transduction in TBC. We shed light on their cross-talk and delineate their roles in obesity as a better understanding of the molecular mechanisms behind their regulation could eventually lead to new strategies to fight against this condition. PMID:24269201

Gilbertson, Timothy A; Khan, Naim A

2014-01-01

229

Pioneer-Venus radio occultation (ORO) data reduction: Profiles of 13 cm absorptivity  

NASA Technical Reports Server (NTRS)

In order to characterize possible variations in the abundance and distribution of subcloud sulfuric acid vapor, 13 cm radio occultation signals from 23 orbits that occurred in late 1986 and 1987 (Season 10) and 7 orbits that occurred in 1979 (Season 1) were processed. The data were inverted via inverse Abel transform to produce 13 cm absorptivity profiles. Pressure and temperature profiles obtained with the Pioneer-Venus night probe and the northern probe were used along with the absorptivity profiles to infer upper limits for vertical profiles of the abundance of gaseous H2SO4. In addition to inverting the data, error bars were placed on the absorptivity profiles and H2SO4 abundance profiles using the standard propagation of errors. These error bars were developed by considering the effects of statistical errors only. The profiles show a distinct pattern with regard to latitude which is consistent with latitude variations observed in data obtained during the occultation seasons nos. 1 and 2. However, when compared with the earlier data, the recent occultation studies suggest that the amount of sulfuric acid vapor occurring at and below the main cloud layer may have decreased between early 1979 and late 1986.

Steffes, Paul G.

1990-01-01

230

RESEARCH Open Access A possible cranio-oro-facial phenotype in  

E-print Network

: retrognathia; micrognathia; high- arched narrow palate; tooth crowding; hypodontia (missing permanent lateral incisor, second premolars or molars), screwdriver shaped incisors, microdontia, radiculomegaly, and enamel

Paris-Sud XI, Université de

231

Oro-nasal fistula of infective origin and alveolar necrosis in a 13 year old boy.  

PubMed

An unusual case of oronasal fistulla of infective origin in a patient with a previous history of aplastic anemia and cancrum oris is discussed here in this report. As the general condition of the patient was not favouring the surgical closure, an obturator was fabricated and inserted to relieve the problems of regurgitation of food and fluids into the nasal cavity. PMID:15915633

Jayasankar, P Pillai; Chavda, Jyoti; Shah, Raksha M

2004-01-01

232

FLUOROSCOPIC EVALUATION OF ORO-PHARYNGEAL DYSPHAGIA: ANATOMY, TECHNIQUE, AND COMMON ETIOLOGIES  

PubMed Central

Target Audience Radiologists and other professionals involved in imaging of oropharyngeal swallowing Objectives To review anatomy of the upper GI tract To review techniques and contrast agents used in the fluoroscopic examination of the oropharynx and hypopharynx To provide a pictorial review of some important causes of oropharyngeal dysphagia, and to link these to key findings in the clinical history to assist in establishing a clinical diagnosis To provide self-assessment questions to reinforce key learning points PMID:25539237

Edmund, Dr; Au, Frederick Wing-Fai; Steele, Catriona M.

2015-01-01

233

The crystal structures of the calcium-bound con-G and con-T[K7gamma] dimeric peptides demonstrate a metal-dependent helix-forming motif.  

PubMed

Short peptides that have the ability to form stable alpha-helices in solution are rare, and a number of strategies have been used to produce them, including the use of metal chelation to stabilize folding of the backbone. However, no example exists of a structurally well-defined helix stabilized exclusively through metal ion chelation. Conantokins (con)-G and -T are short peptides that are potent antagonists of N-methyl-D-aspartate receptor channels. While con-G exhibits no helicity alone, it undergoes a structural transition to a helical conformation in the presence of a variety of multivalent cations, especially Mg2+ and Ca2+. This complexation also results in antiparallel dimerization of two peptide helices in the presence of Ca2+, but not Mg2+. A con-T variant, con-T[K7gamma], displays very similar behavior. We have solved the crystal structures of both Ca2+/con-G and Ca2+/con-T [K7gamma] at atomic resolution. These structures clearly show the nature of the metal-dependent dimerization and helix formation and surprisingly also show that the con-G dimer interface is completely different from the con-T[K7gamma] interface, even though the metal chelation is similar in the two peptides. This represents a new paradigm in helix stabilization completely independent of the hydrophobic effect, which we define as the "metallo-zipper." PMID:17243678

Cnudde, Sara E; Prorok, Mary; Dai, Qiuyun; Castellino, Francis J; Geiger, James H

2007-02-14

234

Deutsche Bank Deutsche Bank S.p.A. la consociata italiana di Deutsche Bank AG che, con oltre  

E-print Network

Deutsche Bank Deutsche Bank S.p.A. è la consociata italiana di Deutsche Bank AG che, con oltre 100.000 collaboratori in più di 72 Paesi nel mondo, vanta più di 24 milioni di clienti. Deutsche Bank ricerca brillanti laureati con ottime capacità relazionali, realizzative e cognitive. Posizione Addetto Personal Banking

Robbiano, Lorenzo

235

76 FR 54533 - Pipeline Safety: Issuance of Draft Decision on GexCon US, Inc. Petition for Approval of Flame...  

Federal Register 2010, 2011, 2012, 2013

...Decision on GexCon US, Inc. Petition for Approval of Flame Acceleration Simulator AGENCY: Pipeline and Hazardous Materials Safety...Decision on GexCon US, Inc.'s petition for approval of Flame Acceleration Simulator (FLACS). The Draft Decision is available...

2011-09-01

236

Añadir quimioterapia después de la radioterapia mejora la supervivencia de adultos con un tipo de tumor cerebral de crecimiento lento  

Cancer.gov

Adultos con gliomas de grado bajo, una forma de tumor cerebral, que recibieron tratamiento con quimioterapia después de la radioterapia vivieron más tiempo que pacientes que recibieron solo radioterapia, según los resultados de seguimiento a largo plazo de un estudio clínico aleatorizado y controlado, subvencionado por los NIH.

237

Comparacion internacional del gasto publico en Sanidad y Educacion de España con los paises de la OCDE 1982-96  

Microsoft Academic Search

En este trabajo analizamos el nivel del gasto publico en Sanidad y Educacion de España comparandolo con otros paises europeos y de la OCDE. El analisis incluye un modelo econometrico que estima la elasticidad del gasto con respecto al PIB y al numero de estudiantes. La principal conclusion es que España tiene un nivel bajo de gasto total, publico y

Isabel Neira; Ana Iglesias

2001-01-01

238

Trabajo con Comunidades y Grupos : dominación y resistencia. Procesos que nos llevan a plantear tareas permanentes y cotidianas  

Microsoft Academic Search

Este trabajo presenta algunas ideas con respecto a las tareas permanentes y cotidianas, que se sugieren considerar en el trabajo colectivo en las comunidades y con los grupos en los que participamos. La convivencia humana, como práctica socio-cultural se convierte en una de las vivencias más complejas e importantes que son capaces de gestar lo que en el mundo actual

Teresa Cordero Cordero

2006-01-01

239

14th World Congress of IFACA FINITE-DIMENSIONAL CODER-ESTIMATOR FOR RATE-CONS... Copyright 1999 IFAC  

E-print Network

14th World Congress of IFACA FINITE-DIMENSIONAL CODER-ESTIMATOR FOR RATE-CONS... Copyright © 1999;14th World Congress of IFACA FINITE-DIMENSIONAL CODER-ESTIMATOR FOR RATE-CONS... ISBN: 0 08 043248 4Copyright 1999 IFAC #12;14th World Congress of IFACA FINITE-DIMENSIONAL CODER-ESTIMATOR FOR RATE

Nair, Girish

240

A brief guide to access the Wound Healing and Management (WHAM) Node via JBI COnNECT+  

E-print Network

A brief guide to access the Wound Healing and Management (WHAM) Node via JBI COnNECT+ To access JBI COnNECT+ and the Wound Healing and Management Node go to JBI Homepage at http and password are both the same word: - wound. #12; To go directly to the Wound Healing and Management Node

241

Probing of Brain States in Real-Time: Introducing the ConSole Environment  

PubMed Central

Recent years have seen huge advancements in the methods available and used in neuroscience employing EEG or MEG. However, the standard approach is to average a large number of trials for experimentally defined conditions in order to reduce intertrial-variability, i.e., treating it as a source of “noise.” Yet it is now more and more accepted that trial-to-trial fluctuations bear functional significance, reflecting fluctuations of “brain states” that predispose perception and action. Such effects are often revealed in a pre-stimulus period, when comparing response variability to an invariant stimulus. However such offline analyses are disadvantageous as they are correlational by drawing conclusions in a post hoc-manner and stimulus presentation is random with respect to the feature of interest. A more direct test is to trigger stimulus presentation when the relevant feature is present. The current paper introduces Constance System for Online EEG (ConSole), a software package capable of analyzing ongoing EEG/MEG in real-time and presenting auditory and visual stimuli via internal routines. Stimulation via external devices (e.g., transcranial magnetic stimulation) or third-party software (e.g., PsyScope X) is possible by sending TTL-triggers. With ConSole it is thus possible to target the stimulation at specific brain states. In contrast to many available applications, ConSole is open-source. Its modular design enhances the power of the software as it can be easily adapted to new challenges and writing new experiments is an easy task. ConSole is already pre-equipped with modules performing standard signal processing steps. The software is also independent from the EEG/MEG system, as long as a driver can be written (currently two EEG systems are supported). Besides a general introduction, we present benchmark data regarding performance and validity of the calculations used, as well as three example applications of ConSole in different settings. ConSole can be downloaded at: http://console-kn.sf.net. PMID:21716603

Hartmann, Thomas; Schulz, Hannah; Weisz, Nathan

2011-01-01

242

Air Traffic Management Technology Demonstration-1 Concept of Operations (ATD-1 ConOps)  

NASA Technical Reports Server (NTRS)

The operational goal of the ATD-1 ConOps is to enable aircraft, using their onboard FMS capabilities, to fly Optimized Profile Descents (OPDs) from cruise to the runway threshold at a high-density airport, at a high throughput rate, using primarily speed control to maintain in-trail separation and the arrival schedule. The three technologies in the ATD-1 ConOps achieve this by calculating a precise arrival schedule, using controller decision support tools to provide terminal controllers with speeds for aircraft to fly to meet times at a particular meter points, and onboard software providing flight crews with speeds for the aircraft to fly to achieve a particular spacing behind preceding aircraft.

Baxley, Brian T.; Johnson, William C.; Swenson, Harry; Robinson, John E.; Prevot, Thomas; Callantine, Todd; Scardina, John; Greene, Michael

2012-01-01

243

Decay estimates for a nonlocal p-Laplacian evolution problem with mixed boundary con-  

E-print Network

Decay estimates for a nonlocal p-Laplacian evolution problem with mixed boundary con- ditions Ra p-Laplacian evolution problem with mixed boundary conditions, that is, ut(x, t) = 0 J(x - y)|u(y, t) - u(x, t)|p-2 (u(y, t) - u(x, t)) dy for (x, t) Ã? R+ and u(x, t) = 0 in 0 Ã? R+ . The proof

Rossi, Julio D.

244

Pro/con debate: Is etomidate safe in hemodynamically unstable critically ill patients?  

PubMed Central

Etomidate is an induction agent known for its smooth intubating conditions and cardiovascular stability. Studies, however, have shown that a single dose of etomidate can result in a prolonged adrenal insufficiency. The impact of this in patients with sepsis has been a matter for debate. This review presents a pro/con case for using etomidate in hemodynamically unstable critically ill patients and provides guidance for alternative induction techniques and when the use of etomidate might be justified despite these concerns. PMID:22809235

2012-01-01

245

Video Phone 4.3 Inch LCD Display, Touch Screen , RemoCon  

E-print Network

Connector · Network Interface ­ Two(2) 10/100Mbps Fast Ethernet (RJ45) ­ One(1) RS-232C Interface (RJ45 Video In/Out Audio In/Out Fast Ethernet (LAN,WAN) RS232C Console #12;6 · Various Video Networking Number Register Recent Call Speed Dial IrDA RemoCon #12;13 Network Setup OSD (VoIP, LAN, etc) Internet

246

NASA KSC/AFRL Reusable Booster System (RBS) Concept of Operations (ConOps)  

NASA Technical Reports Server (NTRS)

This slide presentation reviews the study and findings of the study on the Concept of Operations (ConOps) for Reusable Booster System (RBS) centering on rapid turnaround and launch of a two-stage partially reusable payload delivery system (i.e., 8 hours between launches). The study was to develop rapid ground processing (aircraft like concepts) and identify areas for follow-on study, technology needs, and proof-of-concept demonstrations.

Zeno, Dnany; Mosteller, Ted; McCleskey, Carey; Jhnson, Robert; Hopkins, Jason; Miller, Thomas

2010-01-01

247

IAU Symp. 240: Binary Stars as Critical Tools & Tests in Con-temporary Astrophysics  

E-print Network

IAU Symp. 240: Binary Stars as Critical Tools & Tests in Con- temporary Astrophysics Proceedings Astronomical Union DOI: 00.0000/X000000000000000X EUVE J0825-16.3 and EUVE J1501-43.6: two dMe double telescope confirm the binary nature of the dMe stars EUVE J0825-16.3 and EUVE J1501-43.6, previously

Complutense de Madrid, Universidad

248

Foglio di esercizi N. 3 1. Con il linguaggio degli "o-piccolo": per x 0  

E-print Network

Foglio di esercizi N. 3 1. Con il linguaggio degli "o-piccolo": per x 0 2x = 1 + x log 2 + o(x), 3x = 1 + x log 3 + o(x), quindi 2x - 3x = (log 2 - log 3)x + o(x). Dato che -1 sin 1 x 1, si ha -x x sin 1 x x, e quindi (per il teorema dei due carabinieri) lim x0+ x sin 1 x = 0, ovvero x sin 1 x

Tauraso, Roberto

249

Disfrute del sol con cuidado -- Cualquier persona puede padecer cáncer de piel  

Cancer.gov

Está bien pasar algún tiempo al aire libre, pero usted debe saber que las personas de piel más oscura –incluso muchos hispanos o latinos– tienen riesgo de padecer cáncer de piel. Siempre que pueda, evite exponerse al sol, especialmente entre las 10 a.m. y las 4 p.m., cuando los rayos del sol son más fuertes. Si trabaja o juega al aire libre, cúbrase y protéjase la piel con prendas de vestir, sombreros, lentes, filtros solares.

250

Mound-ACT*DE*CON{sup SM} feasibility study. Phase 2: Final report  

SciTech Connect

A portion of the abandoned Miami-Erie Canal paralleling the Greater Miami River receives the runoff and storm-water discharge from Mound Laboratory. In 1969, a low-level plutonium leak contaminated sediment as far away as 1.5 mi from the Mound site along the old canal system. An estimated one million cubic feet of sediment requires remediation. The technology being evaluated for the remediation of the low-level plutonium-238 contamination of the sediment involves two processes: washing the sediments with ACT*DE*CON{sup SM} solution to dissolve the contaminant, followed by extraction of the solution and processing with the MAG*SEP{sup SM} process to concentrate the contaminant and allow reuse of the ACT*DE*CON{sup SM} solution. The processes are being optimized for pilot-scale and field demonstration. Phase 2 of the project primarily involved identification at the laboratory scale of the optimal ACT*DE*CON{sup SM} formulation, identification of the ion-exchanger and MAG*SEP{sup SM} particles, verification of the plutonium mobility in the treated soil, and evaluation of other process parameters according to a series of tasks.

NONE

1994-12-01

251

The Transcription Factor Con7-1 Is a Master Regulator of Morphogenesis and Virulence in Fusarium oxysporum.  

PubMed

Previous studies have demonstrated the essential role of morphogenetic regulation in Fusarium oxysporum pathogenesis, including processes such as cell-wall biogenesis, cell division, and differentiation of infection-like structures. We identified three F. oxysporum genes encoding predicted transcription factors showing significant identities to Magnaporthe oryzae Con7p, Con7-1, plus two identical copies of Con7-2. Targeted deletion of con7-1 produced nonpathogenic mutants with altered morphogenesis, including defects in cell wall structure, polar growth, hyphal branching, and conidiation. By contrast, simultaneous inactivation of both con7-2 copies caused no detectable defects in the resulting mutants. Comparative microarray-based gene expression analysis indicated that Con7-1 modulates the expression of a large number of genes involved in different biological functions, including host-pathogen interactions, morphogenesis and development, signal perception and transduction, transcriptional regulation, and primary and secondary metabolism. Taken together, our results point to Con7-1 as general regulator of morphogenesis and virulence in F. oxysporum. PMID:25271883

Ruiz-Roldán, Carmen; Pareja-Jaime, Yolanda; González-Reyes, José Antonio; G-Roncero, M Isabel

2015-01-01

252

Con_A-carbone nanotube conjugate with short wave near-infrared laser ablation for tumor therapy  

NASA Astrophysics Data System (ADS)

Using the characteristics of T cell mitogen called lectin protein from the jack-beam Canavalia ensiformis Concanavalin A (Con_A) with dual activities, cytotoxicity and immunomodulation, we have shown it has a therapeutic effect on hepatoma. Injection of Con_A can eradicate the established malign tumor, because Con_A can induce tumor cell autophagic, cell-programmed death, as well as activate the effector T cells. Combined, in this paper, with the absorption exceeding the Carbon NanoTube (CNT) band-gap (?bg=~1/CNT diameter) with an active short wave near-infrared (SWIR) (1.2~1.5 micron wavelengths), which happened to be translucent to the irradiation upon animal skin, similar to that used in hospital fingertip-clamped Pulse Oxymetry. Once the Con_ACNT is guided to hepatoma cells, it is bonded and internalized into the mitochondria (MC) compartment, the cellular energy factory. Con_A has the higher specificity for tumor cells useful for targeting because of the abnormal glycosylation on tumor cells. When CNT hitch hike with Con_A, they can t together like a laser-denotable chemical missile surgically targeting at the tumor cells precisely by Con_A-guidance. We switch on SWIR laser, when the Con_A-CNT conjugated complex has been bonded and internalized to MC of malign cells and already commenced cellular programmed death. Thus, it might appear to casual readers that we have initiated an overkill, chemical drugged autophage followed with physical laser ablation, but what if we can eradicate hepatoma totally if no blue print is left behind inadvertently in case of a partial failure. We conclude that using Con_A-CNT conjugated complex targeting specifically at malign tumor cells is a novel targeted-laser-radiation therapy for tumors in mice.

Lei, Huan-Yao; Peng, Ching-An; Tang, Ming-Jer; Reindhart, Kit; Szu, Harold H.

2009-04-01

253

Caos en el mercado de commodities  

Microsoft Academic Search

Este artículo aplica seis técnicas y herramientas (análisis gráfico, gráfico de recurrencia, entropía de espacio temporal, coeficiente de Hurst, exponente de Lyapunov y dimensión de correlación), a las series de retornos del cobre, oro, petróleo, plata, zinc, aluminio, plomo y níquel, con el fin de corroborar la existencia de un comportamiento caótico en el mercado de commodities. Se encuentra evidencia

Christian Espinosa Méndez

2010-01-01

254

Los NIH anuncian el lanzamiento de 3 estudios integrados de medicina de precisión; ALCHEMIST es para pacientes con ciertos tipos de cáncer de pulmón en estadio inicial  

Cancer.gov

Los Estudios sobre la Secuenciación e Identificación de Marcadores para el Mejoramiento de la Terapia Adjuvante para el Cáncer de Pulmón, conocidos con el nombre de ALCHEMIST, identificarán a pacientes con cáncer de pulmón en estadio inicial cuyos tumores albergan ciertos cambios genéticos, y evaluarán si los tratamientos con medicamentos que actúan sobre esos cambios pueden mejorar la supervivencia.

255

Analytical studies of groundwater-head uctuation in a coastal conned aquifer overlain by a semi-permeable layer with storage  

E-print Network

in the groundwater- head ¯uctuation in the con®ned aquifer. While leakage is generally more important than storage greater than the storage coecient of the con®ned aquifer. This assumption may not be valid whenAnalytical studies of groundwater-head ¯uctuation in a coastal con®ned aquifer overlain by a semi

Jiao, Jiu Jimmy

256

The rights, tensions, and ideas that inform the con-temporary human experience were explored by the  

E-print Network

The rights, tensions, and ideas that inform the con- temporary human experience were explored Trustee. Examining the Human Experience ANDREAKANE CLIFFMOORE #12;; and the conception and challenges of human rights from historical, philo- sophical, political, and sociological

257

32 Wesley C. Salmon -it has been appropriate to deny that such appeals to functions involve the con-  

E-print Network

32 Wesley C. Salmon -it has been appropriate to deny that such appeals to functions involve the con's (1962) defense of deductive explanation in her contribution to the third volume #12;34 Wesley C. Salmon

Fitelson, Branden

258

The Credibility Revolution in Empirical Economics: How Better Research Design is Taking the Con out of Econometrics  

E-print Network

Just over a quarter century ago, Edward Leamer (1983) reflected on the state of empirical work in economics. He urged empirical researchers to “take the con out of econometrics” and memorably observed (p. 37): “Hardly ...

Angrist, Joshua

2010-01-01

259

Extenso estudio realizado en muchos centros demuestra que hay una precisión comparable de la colonoscopia virtual con la colonoscopia convencional  

Cancer.gov

Según los resultados del Estudio Nacional de Colografía de Tomografía Computarizada de la American College of Radiology Imaging Network, ACRIN, la colografía de tomografía computarizada, también conocida como colonoscopia virtual, es comparable a la colonoscopia convencional en su capacidad para detectar con precisión cáncer y pólipos precancerosos y podría servir como examen selectivo inicial de detección de cáncer colorrectal. La colonoscopia convencional usa un tubo largo, flexible, con cámara, para ver el revestimiento del colon.

260

Víctimas y victimarios: Cómplices del discurso del poder en Una noche con el Sr. Magnus e hijos de Ricardo Monti  

E-print Network

FALL 1989 37 Víctimas y victimarios: Cómplices del discurso del poder en Una noche con el Sr. Magnus e hijos de Ricardo Monti Roberto Previdi Froelich ... porque nunca podemos odiar a las personas que sabemos son capaces de hacer exactamente... en los lados ocultos que encarnan la sutil naturaleza de la ideología burguesa en su discurso del poder. Si bien presenciamos una evidente ruptura con una construcción tradicional del realismo teatral,1 el teatro de Monti, a través de sus...

Previdi Froelich, Roberto

1989-10-01

261

Esercizi quarta settimana1 Determinare lo sviluppo asintotico delle seguenti funzioni nella scala delle potenze per x 0 con  

E-print Network

delle potenze per x 0 con almeno tre termini consecutivi: ex - sin x - 1 sinh2 x (1 - cosh x) sin x 3 x + x4 cos sin x sin(1 - cos x) esin x cos x + sin x ex2 Determinare lo sviluppo asintotico delle seguenti funzioni nella scala delle potenze per x + con almeno tre termini consecutivi: 3 x + x4 sinh sin

Marconi, Umberto

262

Presentación del estudio “Links” de hombres que tienes sexo con hombres en Buenos Aires, Argentina  

PubMed Central

Resumen Estudios previos en Buenos Aires reportaron altas prevalencias de HIV entre HSH, con valores que oscilan entre 9 y 14% durante casi 10 años de continuo testeo. El objetivo principal de este estudio fue la evaluación de factores relacionados al comportamiento de alto riesgo para transmisión del HIV entre HSH entre los que se incluyen el conocimiento y factores emocionales, socioculturales y ambientales. Por otro lado se realizó la estimación de prevalencia e incidencia de HIV utilizando RDS (Respondent Driven Sampling), así como la presencia de otras infecciones de transmisión sexual. Por último se evaluaron los hábitos de testeo para HIV indagando que factores facilitan o impiden su realización. El estudio constó de dos fases, en primer lugar una fase cualitativa y posteriormente una fase cuantitativa con una duración total de 4 años y medio. Durante la fase cualitativa se realizaron 44 entrevistas individuales en profundidad, 8 grupos focales y 10 observaciones etnográficas (hoteles, baños públicos (“teteras”), cines pornográficos, fiestas privadas, dark rooms y discotecas). Durante la fase cuantitativa del estudio se realizó el reclutamiento de 500 participantes que provinieron de la Ciudad Autónoma de Buenos Aires, así como del Gran Buenos Aires. El reclutamiento se comenzó con 16 participantes llamados semillas. Se realizó el diagnóstico de infección por HIV, hepatitis B y C (HBV y HCV), Treponema pallidum, Virus Papiloma Humano (HPV) y Chlamidias. La colaboración establecida entre los grupos de trabajo enfocados en áreas diversas posibilitó el abordaje conjunto de nuevas estrategias de investigación antes no exploradas en nuestro país. Los resultados más relevantes de esta investigación serán progresivamente publicados en sucesivos números de Actualizaciones en SIDA. PMID:25264397

Carballo-Diéguez, Alex; Ávila, María M; Balán, Iván C.; Marone, Rubén; Pando, María A.; Barreda, Victoria

2011-01-01

263

Perceived pros and cons of smoking and quitting in hard-core smokers: a focus group study  

PubMed Central

Background In the last decade, so-called hard-core smokers have received increasing interest in research literature. For smokers in general, the study of perceived costs and benefits (or ‘pros and cons’) of smoking and quitting is of particular importance in predicting motivation to quit and actual quitting attempts. Therefore, this study aims to gain insight into the perceived pros and cons of smoking and quitting in hard-core smokers. Methods We conducted 11 focus group interviews among current hard-core smokers (n = 32) and former hard-core smokers (n = 31) in the Netherlands. Subsequently, each participant listed his or her main pros and cons in a questionnaire. We used a structural procedure to analyse the data obtained from the group interviews and from the questionnaires. Results Using the qualitative data of both the questionnaires and the transcripts, the perceived pros and cons of smoking and smoking cessation were grouped into 6 main categories: Finance, Health, Intrapersonal Processes, Social Environment, Physical Environment and Food and Weight. Conclusions Although the perceived pros and cons of smoking in hard-core smokers largely mirror the perceived pros and cons of quitting, there are some major differences with respect to weight, social integration, health of children and stress reduction, that should be taken into account in clinical settings and when developing interventions. Based on these findings we propose the ‘Distorted Mirror Hypothesis’. PMID:24548463

2014-01-01

264

Fully digital control of a three phase UPS by VeCon integrated controller  

SciTech Connect

This paper presents a fully digital control technique for voltage-fed three-phase inverters to be used in uninterruptible power supplies. An application-specific digital signal processor (VeCon) is used to attain the regulation of the output voltages, which is maintained also in presence of wide load variations. After a short description of the system, attention is focused on VeCon`s performances and implemented control algorithm. Even if no transformer is used in the power converter, the line-to-neutral voltages are independently controlled thus allowing supply of single-phase or unbalanced loads. An inner current control loop is implemented to provide limitation of the phase currents in case of short circuit and overload. Each current and voltage is controlled by a digital PI regulator. The overall control takes less than 20 {micro}s. Sinusoidal output voltages and well controlled phase currents are attained, as demonstrated by experimental results coming from a 15 kVA prototype.

Rossetto, L.; Malesani, L.; Tenti, P.; Buso, S. [Univ. of Padova (Italy); Pollmann, A. [CEMONT SpA, Rivoli (Italy)

1995-12-31

265

Actitudes Éticas de los estudiantes y egresados en carrera de medicina con metodologías activas  

PubMed Central

El presente estudio tiene por objeto desarrollar un diagnostico de la inserción integrada de la ética en la carrera de medicina brasileña con una metodología de aprendizaje basada en problemas y describir las percepciones de actitudes éticas de los estudiantes y egresados. El diseño metodológico es un estudio de caso, descriptivo y documental, con abordaje cualitativo y cuantitativo. La muestra de esta investigación ha sido constituida por 120 estudiantes y 40 egresados de dos promociones del Curso de Medicina de la ESCS. Este proyecto fue aprobado por el Comité de Ética en Investigación - SES/DF. Los estudiantes y egresados de la ESCS demostraron un buen manejo en el abordaje de los conflictos éticos y respeto a los pacientes. Sin embargo, el análisis de sensibilidad ética mostró una fragilidad en las percepciones y aptitudes inapropiadas de los estudiantes de la carrera de medicina, identificada básicamente en los años iniciales, que necesitan más discusiones sistematizadas sobre los aspectos éticos y bioéticos integrados a las actividades prácticas para estimular y fortalecer la reflexión ética de los estudiantes. PMID:20981242

Novaes, Maria Rita Carvalho Garbi; Novaes, Luiz Carlos Garcez; Guilhem, Dirce; Stepke, Fernando Lolas; Silveira, Carla Cristina Costa; Komatsu, Ricardo Shoiti; Trindade, Eliane Mendonça Vilar; Guiotti, Murilo Galvão

2010-01-01

266

Feeding of grey squirrels (Sciurus carolinensis) with the contraceptive agent DiazaCon™: effect on cholesterol, hematology, and blood chemistry.  

PubMed

Grey squirrels (Sciurus carolinensis) are an invasive species in Britain and Italy. They have replaced native red squirrels (Sciurus vulgaris) throughout most of Britain, and cause damage to trees. Currently, lethal control is used to manage grey squirrel populations in Britain, but nonlethal methods might be more acceptable to the public. One such method is contraception with 20,25-diazacholesterol dihydrochloride (DiazaCon™). DiazaCon™ inhibits the conversion of desmosterol to cholesterol, resulting in increasing desmosterol concentrations and decreasing cholesterol concentrations. Because cholesterol is needed for the synthesis of steroid reproductive hormones, such as progesterone and testosterone, inhibition of cholesterol synthesis indirectly inhibits reproduction. Desmosterol is used as a marker of efficacy in laboratory studies with species that do not reproduce readily in captivity. Grey squirrels were gavaged with a DiazaCon™ solution for 2 days, and then fed DiazaCon™-coated peanuts for an additional 8 days at target doses of 50 and 100 mg DiazaCon™ per kg body weight. There was a significant difference in cholesterol concentrations in the treatment groups compared to the control group. Cholesterol was reduced by ? 40% for 2 months in both treatment groups. There were no differences among groups with respect to blood chemistry and hematology parameters, and mean values are reported. The mean overall dose of DiazaCon™ received was 29.0 ± 1.6 and 55.3 ± 4.3 mg/kg in the low (50 mg/kg) and high dose (100 mg/kg) groups, respectively. DiazaCon™ might provide an effective, acceptable alternative to lethal control. PMID:22182332

Yoder, Christi A; Mayle, Brenda A; Furcolow, Carol A; Cowan, David P; Fagerstone, Kathleen A

2011-12-01

267

Nest destruction elicits indiscriminate con- versus heterospecific brood parasitism in a captive bird.  

PubMed

Following nest destruction, the laying of physiologically committed eggs (eggs that are ovulated, yolked, and making their way through the oviduct) in the nests of other birds is considered a viable pathway for the evolution of obligate interspecific brood parasitism. While intraspecific brood parasitism in response to nest predation has been experimentally demonstrated, this pathway has yet to be evaluated in an interspecific context. We studied patterns of egg laying following experimental nest destruction in captive zebra finches, Taeniopygia guttata, a frequent intraspecific brood parasite. We found that zebra finches laid physiologically committed eggs indiscriminately between nests containing conspecific eggs and nests containing heterospecific eggs (of Bengalese finches, Lonchura striata vars. domestica), despite the con- and heterospecific eggs differing in both size and coloration. This is the first experimental evidence that nest destruction may provide a pathway for the evolution of interspecific brood parasitism in birds. PMID:25512846

Shaw, Rachael C; Feeney, William E; Hauber, Mark E

2014-12-01

268

The new human papillomavirus (HPV) vaccine: pros and cons for pediatric and adolescent health.  

PubMed

The new human papillomavirus (HPV) vaccine is a research breakthrough for pediatric/adolescent health to prevent cervical cancer and related morbidity. The annual heath care cost for the treatment of cervical cancer and genital warts is estimated to be more than three billion dollars a year. The new HPV vaccine has incredible potential to improve reproductive health promotion, reduce health care costs, and close health care disparity gaps. However, issues both for and against the new HPV vaccine, including mandating vaccination, high cost of the vaccine, the short duration of protection offered, and the perceived promotion of sexual activity, cause confusion. Pediatric nurses, including those in advanced practice, benefit by understanding the pros and cons of these issues in advocating for their patients. PMID:19051848

Thomas, Tami L

2008-01-01

269

Multipotent (adult) and pluripotent stem cells for heart regeneration: what are the pros and cons?  

PubMed Central

Heart failure after myocardial infarction is the leading cause of mortality and morbidity worldwide. Existing medical and interventional therapies can only reduce the loss of cardiomyocytes during myocardial infarction but are unable to replenish the permanent loss of cardiomyocytes after the insult, which contributes to progressive pathological left ventricular remodeling and progressive heart failure. As a result, cell-based therapies using multipotent (adult) stem cells and pluripotent stem cells (embryonic stem cells or induced pluripotent stem cells) have been explored as potential therapeutic approaches to restore cardiac function in heart failure. Nevertheless, the optimal cell type with the best therapeutic efficacy and safety for heart regeneration is still unknown. In this review, the potential pros and cons of different types of multipotent (adult) stem cells and pluripotent stem cells that have been investigated in preclinical and clinical studies are reviewed, and the future perspective of stem cell-based therapy for heart regeneration is discussed. PMID:24476362

2013-01-01

270

A new look at the infrared spectrum of the weakly bound CO-N2 complex.  

PubMed

A broad-band (2135-2165 cm(-1)) infrared spectrum of the CO-N2 van der Waals complex is obtained, using a tunable quantum cascade laser to probe a pulsed supersonic expansion from a slit jet source. Analysis of the spectrum results in the characterization of four new 'stacks' of rotational levels for CO-orthoN2 (all in the v(CO) = 1 upper state) and five new stacks for CO-paraN2 (three in the upper state and two in the vCO = 0 lower state). This considerably expands our knowledge of a rather fundamental weakly bound complex and should lead to improved determinations of the intermolecular forces governing interactions between the carbon monoxide and nitrogen molecules. PMID:24090526

Rezaei, Mojtaba; Michaelian, K H; Moazzen-Ahmadi, N; McKellar, A R W

2013-12-19

271

Pro-con debate: etomidate or ketamine for rapid sequence intubation in pediatric patients.  

PubMed

When caring for critically ill children, airway management remains a primary determinant of the eventual outcome. Airway control with endotracheal intubation is frequently necessary. Rapid sequence intubation (RSI) is generally used in emergency airway management to protect the airway from passive regurgitation of gastric contents. Along with a rapid acting neuromuscular blocking agent, sedation is an essential element of RSI. A significant safety concern regarding sedatives is the risk of hypotension and cardiovascular collapse, especially in critically ill patients or those with pre-existing comorbid conditions. Ketamine and etomidate, both of which provide effective sedation with limited effects on hemodynamic function, have become increasingly popular as induction agents for RSI. However, experience and clinical investigations have raised safety concerns associated with both etomidate and ketamine. Using a pro-con debate style, the following manuscript discusses the use of ketamine versus etomidate in RSI. PMID:23118665

Scherzer, Daniel; Leder, Mark; Tobias, Joseph D

2012-04-01

272

Microwave and millimeter wave study of Ortho-N2 states of CO-N2  

NASA Astrophysics Data System (ADS)

Microwave and millimeter wave transitions of the CO-N2 complex were investigated using three different instruments, namely, a pulsed molecular beam Fourier transform microwave spectrometer in the frequency region from 4 to 26 GHz, a microwave-millimeter wave double resonance spectrometer in the frequency regions from 8 to 18 GHz for the microwave and 107-118 GHz for the millimeter wave range, and an OROTRON spectrometer in the frequency range from 107 to 132 GHz. Both a- and b-type transitions associated with the ground-state K=0 levels and the lower K=1 levels of the ortho-N2 states, and with rotational quantum number J up to 19, were measured and analyzed. Nuclear quadrupole hyperfine splittings due to the presence of two equivalent 14N nuclei were resolved and analyzed to give additional information about the angular anisotropy of the interaction potential. The nuclear quadrupole coupling constants obtained are ?aa=0.196 41(52) MHz for K=0 levels, and ?aa=-1.0391(17) MHz, ?bb=0.0633(17) MHz for the lower K=1 levels, respectively. The drastic difference between these two sets of coupling constants suggests that the orientation and motion of the N2 subunit are very different in these two states, and that the complex cannot be adequately described by a semirigid rotor model. In addition, measurements of the rotational spectra of the two new isotopomers containing 13C16O and 13C18O subunits provide further important information about the CO-N2 interaction potential.

Xu, Yunjie; Jäger, Wolfgang; Surin, L. A.; Pak, I.; Panfilov, L. A.; Winnewisser, G.

1999-12-01

273

LISTADO DE CURSOS DE VERANO DISTRIBUIDOS POR SEDE Y POR FECHAS COCENTAINA DISEO DE INSTALACIONES EN EDIFICACIN CON CYPECAD del 16 al 18 de julio de 2012  

E-print Network

EN EDIFICACIÃ?N CON CYPECAD del 16 al 18 de julio de 2012 COCENTAINA EMPRENDE CON Ã?XITO EN INTERNET: CLAVES PARA GENERAR NEGOCIOS ONLINE. del 16 al 20 de julio de 2012 COCENTAINA ORIENTACIÃ?N CON GPS EN EL CAMPO del 19 al 20 de julio de 2012 LA MARINA BENISSA EL ROCK AND ROLL SEGÃ?N SUS MEJORES INTÃ?RPRETES del

Escolano, Francisco

274

NatSci 499 E/F: Integrative Scientific Research (iCons 4; 6 credits) Faculty Contact: Prof. Scott M. Auerbach (iCons Program Director; auerbach@chem.umass.edu) or  

E-print Network

1 NatSci 499 E/F: Integrative Scientific Research (iCons 4; 6 credits) Faculty Contact: Prof. Scott in authentic scientific research in UMass Amherst faculty research laboratories. UMass Amherst offers a rich a capstone research project that identifies and fills a scientific knowledge gap in their chosen theme area

Auerbach, Scott M.

275

Análisis de componentes cognoscitivos y psiquiátricos en pacientes con demencia frontotemporal y alzheimer / Analysis of cognitive and psychiatric components in patients with frontotemporal dementia and Alzheimer.  

E-print Network

??Reyes Gavilán, Pablo Alexander (2010) Análisis de componentes cognoscitivos y psiquiátricos en pacientes con demencia frontotemporal y alzheimer / Analysis of cognitive and psychiatric components… (more)

Reyes Gavilán, Pablo Alexander

2010-01-01

276

Basin boundary metamorphoses and phase J. M. Seoane, S. Zambrano, I. P. Mari~no and M. A. F. Sanjuan  

E-print Network

and the fractal dimension of the corresponding boundaries when this phenomenon occurs. Finally, Melnikov analysis critical value, is called basin boundary meta- morphosis (BBM) [1,2]. In this sense some works haveOFFPRINT Basin boundary metamorphoses and phase control J. M. Seoane, S. Zambrano, I. P. Mari

Rey Juan Carlos, Universidad

277

ScholarShip programS conSideration given to the following min Sat awardS given  

E-print Network

ScholarShip programS conSideration given to the following min Sat (freShmen) and/or gpa number of awardS given & amount renewable? SCHOLARSHIPS AWARDED THROUGH THE UNIVERSITY HONORS PROGRAM University Honors Program Scholarship Incoming freshmen and transfer students who are intellectually curious

Hutcheon, James M.

278

La Universidad de Alicante premiar el robot hecho por amateurs ms hbil en carreras con otros y pinchando sus globos  

E-print Network

La Universidad de Alicante premiará el robot hecho por amateurs más hábil en carreras con otros y Competición de Robótica Amateur UA, está destinado prioritariamente a estudiantes de esta universidad y forma

Escolano, Francisco

279

Global trade in dairy products involves complex and con-tentious issues. Viewed broadly from the perspective of  

E-print Network

Global trade in dairy products involves complex and con- tentious issues. Viewed broadly from the perspective of "society," there are large benefits from liberalizing trade. Viewed narrowly from the perspective of dairy producers, liberalized trade is desirable only if it expands exports and reduces imports

Radeloff, Volker C.

280

Mecanismos psicofisiológicos implicados en la regulación afectiva y la restricción alimentaria de mujeres con riesgo de padecer bulimia nerviosa  

Microsoft Academic Search

El objetivo del estudio fue conocer el efecto de visualizar imágenes de comida bajo diferentes estados de ánimo y diferentes condiciones de restricción alimentaria en la modulación emocional de dos refle- jos defensivos (sobresalto motor y defensa cardiaca). 72 mujeres con riesgo de padecer bulimia ner- viosa fueron asignadas a dos grupos: 1) un grupo al que se inducía un

Sonia Rodríguez; José Luis Mata; Silvia Moreno; Jaime Vila

2007-01-01

281

Sndrome de Waterhouse-Friderichsen: Ms eficacia en el tratamiento con el uso precoz de Protena-C ?  

E-print Network

Síndrome de Waterhouse-Friderichsen: Más eficacia en el tratamiento con el uso precoz de Proteína uniformizados = ... Introducción: Necesidad de mejora del tratamiento del Síndrome de Waterhouse­ Friderichsen

Manstein, Dietmar J.

282

Genova Silicon Valley 10th Edition Incontro a Economia con Ettore Leale, 29 novembre , ore 17, aula Embriaco  

E-print Network

Genova Silicon Valley 10th Edition Incontro a Economia con Ettore Leale, 29 novembre , ore 17, aula Embriaco E' partito da Genova, nel 2005, il ponte tra Italia e Silicon Valley a beneficio degli studenti social network www.siliconvalleystudytour.com, hanno partecipato alle 9 edizioni del Silicon Valley Study

Robbiano, Lorenzo

283

Analysis of Hook Formation Mechanism in Ultra Low Carbon Steel using CON1D Heat Flow Solidification Model  

E-print Network

Analysis of Hook Formation Mechanism in Ultra Low Carbon Steel using CON1D Heat Flow carbon steel, Continuous casting process, Hook formation, Heat flow, Initial solidification Abstract Subsurface hook formation at the meniscus during the continuous casting of steel slabs is an important cause

Thomas, Brian G.

284

Desarrollo economico de Europa Central en 1950-2002: Modelos econometricos y comparacion con Irlanda, España y Austria  

Microsoft Academic Search

Analizamos el desarrollo económico de cinco países de Europa Central: Polonia, Hungría, República Checa, Eslovenia y Eslovaquia, durante el período 1950-2002. teniendo en cuenta las diferentes etapas de su evolución, en comparación con tres países de Europa Occidental que tenían al comienzo del período analizado niveles similares de renta por habitante, pero que alcanzaron durante las últimas décadas del siglo

Maria-Carmen GUISAN; Eva AGUAYO

2004-01-01

285

Una economía de frontera con el norte Europeo: El desarrollo de Cataluña en los siglos XVIII al XX  

Microsoft Academic Search

El presente ensayo pretende evaluar la contribución que haya podido suponer la condición de territorio de frontera a las particularidades del proceso de desarrollo económico de Cataluña desde el siglo XVIII en adelante. En su mismo nacimiento como espacio político y administrativo diferenciado y con soberanía sobre el territorio, Cataluña fue una frontera o límite: la “Marca Hispánica” que el

Jordi Maluquer de Motes i Bernet

2001-01-01

286

The driver of a sports utility vehicle that overturned last April, killing a Virginia Tech freshman, was con-  

E-print Network

, was con- victed Monday of reckless driving. Jeffrey Stoudt, a sophomore psychology major at Tech in whole- sale value." Virginia tree growers and sell- ers are fearing the worst, said Rick Dungey of the National Christmas Tree Association. "This has got so many consum- ers scared to death," he said. "It

Beex, A. A. "Louis"

287

Adding Photos Lightbox GalleryCon nued 1 .Toad d im agestoM ood le,inyourtexted itor,  

E-print Network

Adding Photos Lightbox GalleryCon nued 1 .Toad d im agestoM ood le,inyourtexted itor, locate,create a com pressed fold er (.z ip) w ithallthe im agesyou w ould like toad d to the Lightbox Gallery. 2.W

Selmic, Sandra

288

have to travel normal to the layer structure. The film thickness must be sufficiently small to keep the con-  

E-print Network

the con- tact resistance low (Fig. 3B). 15. M. Shur, M. Hack, J. G. Shaw, J. Appl. Phys. 66, 3371 (1989); M. Shur and M. Hack, ibid. 55, 3831 (1984). 16. G. Horowitz and P. Delannoy, ibid. 70, 469 (1991

Wang, Zhong L.

289

Cause of injury: Contact with tentacles which con-tain stinging cells that inject venom into the skin.  

E-print Network

JELLYFISH Cause of injury: Contact with tentacles which con- tain stinging cells that inject venom. Prevention: Take care when swimming in areas known to have jellyfish. Tentacles of some species may trail a great distance from the body. Rubber diving suits give protec- tion. Avoid touching jellyfish washed up

290

TECHNOLOGY EVALUATION REPORT: INTERNATIONAL WASTE TECHNOLOGIES/GEO-CON IN SITU STABILIZATION/SOLIDIFICATION - VOLUME IV - UPDATE REPORT  

EPA Science Inventory

The long-term performance tests provide information on the first follow-up sampling and analysis on the SITE program demonstration of the International Waste Technologies additive, and the Geo-Con deep soil mixing equipment. he samples containing PCBs, were collected one year aft...

291

TECHNOLOGY EVALUATION REPORT: INTERNATIONAL WASTE TECHNOLOGIES/GEO-CON IN SITU STABILIZATION/SOLIDIFICATION - VOLUME III - UPDATE REPORT  

EPA Science Inventory

The long-term performance tests provide information on the first follow-up sampling and analysis on the SITE program demonstration of the International Waste Technologies additive, and the Geo-Con deep soil mixing equipment. he samples containing PCBs, were collected one year aft...

292

SITE PROGRAM APPLICATIONS ANALYSIS REPORT, INTERNATIONAL WASTE TECHNOLOGIES/GEO CON IN-SITU STABILIZATION/SOLIDIFICATION  

EPA Science Inventory

An evaluation was performed of the International Waste Technologies (IWT) HWT-20 additive and the Geo-Con, Inc. deep-soil-mixing equipment for an in situ stabilization/solidification process and its applicability as an on-site treatment method for waste site cleanup. emonstration...

293

Advances in the development of quantitative models of foreland basin stratigraphy have outpaced the observational data used to con-  

E-print Network

ABSTRACT Advances in the development of quantitative models of foreland basin stratigraphy have outpaced the observational data used to con- strain the input parameters in such models. Underfilled collision (Dickinson, 1974; Beau- mont, 1981; Allen et al., 1986). The sedimentary infill of foreland basins

294

NOTE PER RICHIESTA DUPLICATO PERGAMENA 1. Compilare la domanda di rilascio duplicato pergamena con marca da bollo di  

E-print Network

Sviluppo e Rapporti con le Imprese ­ Servizio Offerta Formativa Post Laurea ­ Piazza Leonardo da Vinci, 32 Offerta Formativa Post Laurea in Piazza Leonardo da Vinci, 32 ­ Padiglione Nord ­ 1° piano ­ Milano Ritiro titolare presso il Servizio Offerta Formativa e Post Laurea in Piazza Leonardo da Vinci, 32 ­ Padiglione

295

Pros and cons of BCG vaccination in countries with low incidence of tuberculosis.  

PubMed

Preventive bacille Calmette-Guérin (BCG) vaccination, together with case finding and effective chemotherapy, has formed an integral part of the tuberculosis (TB) control program in most countries. In some low-incidence countries the balance of prevention has been more on the side of chemoprophylaxis than of BCG vaccination. The time clearly has come when the strategy of mass BCG vaccination no longer is indicated medically, nor is it cost-effective. The pros and cons of the programs need to be critically evaluated against the present epidemiological background, taking into account the facts that TB, the killer disease, is recovering strength, human immunodeficiency virus infection is on the increase, and multidrug-resistant TB has changed the outcome of this previously fully curable disease. Although no longer appropriate for mass programs, BCG vaccination still should be considered for the protection of selected risk groups in low-incidence countries. The overall efficacy may be of the order 50% to 80%, but the variation is great. Therefore, further research urgently is needed on the effectiveness of BCG as an intervention in local TB programs. PMID:7963444

Tala, E O; Tala-Heikkilä, M M

1994-07-01

296

Assessing ComSciCon 2013: A science communication workshop for STEM graduate students (Invited)  

NASA Astrophysics Data System (ADS)

We report on the efficacy of Communicating Science 2013, a science communication workshop for graduate students. Effective science communication is imperative for the sharing of scientific ideas, continued funding and support from policy makers, and education of the public. Science graduate students are a prime group to target for communication training, as they will be our future scientists, educators, and EPO professionals. To this end, Communicating Science 2013 (ComSciCon), a workshop organized by and for STEM graduate students, was held in June of this year. This workshop taught graduate students from around the nation to effectively communicate science to both their peers and the public. To learn about grad students' attitudes toward science communication and establish the workshop's efficacy, we surveyed the participants both before and after the workshop. This assessment probed topics such as communication preparation the participants have already received, how science communication is perceived in their home department, and what participants gained from the workshop. We report the results here.

Kohler, S.; Ranjan, S.; Sanders, N.; Morey, S.

2013-12-01

297

Estereotipos Sexuales y su Relación con Conductas Sexuales Riesgosas1,2,3  

PubMed Central

Resumen Los estereotipos sexuales son creencias generalmente aceptadas y poco cuestionadas que podrían contribuir a cómo los hombres y las mujeres debemos expresar nuestra sexualidad. Los objetivos de este estudio eran identificar cuántos hombres y mujeres heterosexuales en Puerto Rico endosaban ciertos estereotipos acerca de la sexualidad masculina y femenina y explorar la relación entre el endoso de estos estereotipos sexuales y las actitudes hacia el condón masculino y su uso en relaciones sexuales vaginales Llevamos a cabo un estudio descriptivo-correlacional mediante el cual le administramos dos escalas, una sobre sexualidad masculina y otra sobre sexualidad femenina a un grupo de 429 personas heterosexuales. Encontramos que los hombres endosaron estereotipos sexuales masculinos y femeninos más que las mujeres y que estos tienden a tener una visión más conservadora respecto a la sexualidad femenina que la que tienen sobre su propia sexualidad. Las mujeres, por otra parte, tienden a ver su propia sexualidad y la sexualidad masculina en términos menos estereotipados y más equitativos. También encontramos que a mayor endoso de creencias tradicionales sobre la sexualidad masculina y femenina, peor la actitud hacia el uso del condón masculino. Sin embargo, el endosar estereotipos sexuales masculinos y/o femeninos no se relacionó con el uso del condón. Estos hallazgos contradicen la literatura que sugiere que estos estereotipos sexuales y de género resultan en conductas sexuales de alto riesgo, lo cual tiene implicaciones importantes para el desarrollo e implementación de programas de prevención. PMID:24575164

Pérez-Jiménez, David; Orengo-Aguayo, Rosaura E.

2012-01-01

298

Estudio financiado por los NIH indica un aumento de la supervivencia en hombres con cáncer de próstata metastásico que reciben quimioterapia desde el inicio de la terapia hormonal  

Cancer.gov

Los hombres con cáncer de próstata metastásico sensible a las hormonas que recibieron el fármaco quimioterapéutico docetaxel al inicio de la terapia hormonal convencional vivieron más tiempo que los pacientes que recibieron solo terapia hormonal, de acuerdo con los resultados preliminares de un estudio clínico controlado y aleatorizado patrocinado por los Institutos Nacionales de la Salud (NIH).

299

El control social y su relación con los procesos de formación de capital social y movilidad social: algunos indicios a partir de experiencias en Bogot  

Microsoft Academic Search

Este documento presenta un acercamiento analítico a los posibles efectos provocados por la práctica y el proceso institucional de control social sobre quienes tienen una relación directa o indirecta con estos mecanismos, que se despliegan desde la Contraloría General de la República para cumplir con lo dispuesto en la Constitución Nacional. Estos efectos se establecen a partir de mediciones de

Julián F. Bautista R; Londra T. Niño M; Gemma V. Truke O; Jairo Santander A

2011-01-01

300

Síndrome de Down y cardiopatías congénitas con hipertensión pulmonar severa. Resultados quirúrgicos. Down Syndrome and congenital heart diseases with severe pulmonary hypertension surgical results  

Microsoft Academic Search

RESUMEN La presencia de una hipertensión pulmonar de rango severo es un factor de alto riesgo en el manejo quirúrgico de los pacientes con cardiopatías congénitas, como está demostrado en numerosos estudios referentes a ese tema. El objetivo de este trabajo fue obtener mayor información sobre la evolución posterior a la cirugía cardiaca de los pacientes con Síndrome de Down

Herminia Palenzuela López; Lys Mara; Senra Reyes; Horacio Pérez López; Francisco Carballés García

301

Contributed Paper Rapid Assessment of Risks to a Mobile Marine  

E-print Network

Protegida a Escala de Ecosistema Resumen: Las redes de ´areas marinas protegidas (AMPs) a escala de pastos marinos: uso de redes, cacer´ia por nativos, pesca con redes de arrastre, tr´afico de nav´ios y riesgo, se tendr´ia que disminuir el uso de redes comerciales y la cacer´ia por nativos en ´areas remotas

Marsh, Helene

302

(Con)text-specific effects of visual dysfunction on reading in posterior cortical atrophy.  

PubMed

Reading deficits are a common early feature of the degenerative syndrome posterior cortical atrophy (PCA) but are poorly understood even at the single word level. The current study evaluated the reading accuracy and speed of 26 PCA patients, 17 typical Alzheimer's disease (tAD) patients and 14 healthy controls on a corpus of 192 single words in which the following perceptual properties were manipulated systematically: inter-letter spacing, font size, length, font type, case and confusability. PCA reading was significantly less accurate and slower than tAD patients and controls, with performance significantly adversely affected by increased letter spacing, size, length and font (cursive < non-cursive), and characterised by visual errors (69% of all error responses). By contrast, tAD and control accuracy rates were at or near ceiling, letter spacing was the only perceptual factor to influence reading speed in the same direction as controls, and, in contrast to PCA patients, control reading was faster for larger font sizes. The inverse size effect in PCA (less accurate reading of large than small font size print) was associated with lower grey matter volume in the right superior parietal lobule. Reading accuracy was associated with impairments of early visual (especially crowding), visuoperceptual and visuospatial processes. However, these deficits were not causally related to a universal impairment of reading as some patients showed preserved reading for small, unspaced words despite grave visual deficits. Rather, the impact of specific types of visual dysfunction on reading was found to be (con)text specific, being particularly evident for large, spaced, lengthy words. These findings improve the characterisation of dyslexia in PCA, shed light on the causative and associative factors, and provide clear direction for the development of reading aids and strategies to maximise and sustain reading ability in the early stages of disease. PMID:24841985

Yong, Keir X X; Shakespeare, Timothy J; Cash, Dave; Henley, Susie M D; Warren, Jason D; Crutch, Sebastian J

2014-08-01

303

Do Patient-perceived Pros and Cons of Opioids Predict Sustained Higher-Dose Use?  

PubMed Central

Objectives Chronic opioid therapy (COT) is associated with various adverse outcomes, especially at higher doses, yet little is known about predictors of sustained higher-dose COT. This study aimed to ascertain, among higher-dose COT patients, the association of patient-perceived pros and cons of opioids with continued higher-dose use 1 year later. Methods Patients (N = 1229) in 2 large health plans prescribed ? 50 mg morphine-equivalent dose (MED) per day for chronic non-cancer pain completed a survey assessing opioid benefits and harms. The Prescribed Opioid Difficulties Scale questionnaire assessed psychosocial problems, concerns, benefits, and side effects related to opioid use. Logistic regression models estimated the associations of the reported benefits and problems with higher-dose continuation (? 50 mg MED/d) versus dose reduction (< 50 mg MED/d) 1 year later. Results Over 80% of participants continued higher-dose opioid use at 1 year, regardless of reported problems, concerns, side effects, pain reduction, or perceived helpfulness. Higher scores on the Prescribed Opioid Difficulties Scale Problems subscale (odds ratio = 0.79, 95% confidence interval, 0.68–0.92) and Concerns subscale (odds ratio = 0.76, 95% confidence interval, 0.65–0.90) were negatively associated with higher-dose use 1 year later. Other baseline measures (opioid helpfulness, reduction in pain, number of side effects, and side effect bothersomeness) were not significantly associated with continued higher-dose use. Discussion The large majority of patients continued using higher-dose opioids regardless of baseline characteristics. These findings suggest the difficulty of reducing opioid dose among chronic higher-dose opioid users. PMID:23535150

Thielke, Stephen M.; Turner, Judith A.; Shortreed, Susan M.; Saunders, Kathleen; LeResche, Linda; Campbell, Cynthia I.; Weisner, Constance C.; Korff, Michael V.

2013-01-01

304

GP73 was upregulated in PBMC stimulated with ConA but failed to promote lymphocyte proliferation.  

PubMed

Golgi protein 73-kD (GP73), a type II Golgi transmembrane glycoprotein, is highly expressed in a variety of human diseases, but its physiology and pathology remain unknown. In examining the function of GP73 in the immune system, treatment of human PBMC with ConA significantly increased the intracellular expression of GP73 and its secretion into the culture medium. Two-way MLR and the ConA stimulation assay showed that treatment with purified GP73 protein barely affected the proliferation of PBMC. These results suggest that lymphocyte-secreted GP73 might partially contribute to higher serum GP73 in patients, and secreted GP73 exerts an extremely weak effect on the proliferation of PBMC ex vivo. PMID:25231014

Wang, Fang; Li, Zhaotao; Li, Leike; Hu, Longbo; Xiao, Jing; Su, Zhong; Peng, Tao

2015-03-01

305

Disminución de las tasas de cáncer de seno relacionada con la reducción del uso de terapias de reemplazo hormonal  

Cancer.gov

La tasa de los casos nuevos de cáncer de seno en los Estados Unidos, la cual disminuyó pronunciadamente en 2003, podría estar relacionada con una disminución nacional del uso de terapias de reemplazo hormonal. Las tasas de incidencia de cáncer de seno ajustadas a la edad en mujeres de los Estados Unidos bajaron un 6.7 por ciento en 2003. Durante este mismo período, las recetas médicas para terapias de reemplazo hormonal bajaron rápidamente.

306

Su una teoria bilocale dell’interazione tra una particella con spin 1\\/2 e il campo elettromagnetico  

Microsoft Academic Search

\\u000a Riassunto  Si presenta una teoria bilocale per una particella libera con spin 1\\/2 fondata su una semplice generalizzazione lineare dell’equazione\\u000a di Dirac. Si risolve tale equazione introducendo una condizione di quantizzazione della massa e una nuova condizione supplementare\\u000a che sostituisce la eondizione di Yukawa usata in un precedente lavoro. La generalizzazione della teoria è tale che nelle equazioni\\u000a le coordinate del

E. Minardi

1956-01-01

307

Compacti cations des espaces de con guration dans les sch emas de L. Evain (evain@tonton.univ-angers.fr)  

E-print Network

Compacti#12;cations des espaces de con#12;guration dans les sch#19;emas de Hilbert L. Evain (evain sch#19;ema de Hilbert. Notre d#19;emarche g#19;en#19;eralise et uni#12;e des constructions classiques Schubert-Semple #18;a toute vari#19;et#19;e lisse par l'utilisation de sch#19;emas de Hilbert [LB] et Keel

308

Immunoreactivity for Thymosin Beta 4 and Thymosin Beta 10 in the Adult Rat Oro-Gastro-Intestinal tract  

PubMed Central

Thymosin beta 4 (T?4) and thymosin beta 10 (T?10) are two members of the ?-thymosin family, involved in multiple cellular activities in different organs in multiple animal species. Here we report the expression pattern of T?4 and T?10 in rat tissues, in the gut and in annexed glands. The two peptide were differently expressed: T?4 was absent in salivary glands whereas T?10 was expressed in parotid and in submandibular glands. T?4 was mildly expressed in the tongue and in the esophagus, where T?10 was absent. A similar expression was found in the stomach, ileum and colon mucosa. In pancreas T?4 reactivity was restricted to the Langerhans islet cells; T?4 was also detected in the exocrine cells. Both peptide were not expressed in liver cells. When the rat expression pattern in rat organs was compared to reactivity for T?4 and T?10 in humans, marked differences were found. Our data clearly indicate a species-specific expression of T?4 and T?10, characterized by the actual unpredictability of the expression of these peptides in different cells and tissues. The common high expression of T?4 in mast cells, both in humans and in rats, represents one of the few similarities between these two species. PMID:23807296

Nemolato, S; Ekstrom, J.; Cabras, T.; Gerosa, C.; Fanni, D.; Di Felice, E.; Locci, A.; Messana, I.; Castagnola, M.; Faa, G.

2013-01-01

309

[Cognitive investigation on the quality of life of patients with oro-facial neoplasms in advanced stage].  

PubMed

As part of a Ministry of health founded research project into the quality of life among advanced cancer patients and in collaboration with the National Tumour Institutes of Milan, Naples and Genoa, an investigation was conducted on a national and international scale into the quality of the assistance given to cancer patients. Specific subjects of investigation included: the existence of pain treatment centres, home help and the type of psychological support offered such patients. In addition a questionnaire was presented to Italian oncologists, hospital staff and general practitioners covering areas like deontological problems of information, emotional, responses and quality of treatment. The answers revealed differences in the profiles of these three categories that make a significant contribution to the current discussion of the problem of the quality experienced by advanced cancer patients. PMID:2733668

Cianfriglia, F; De Pisa, E; Girardi, P

1989-04-01

310

trkA MODULATION OF DEVELOPING SOMATOSENSORY NEURONS IN ORO-FACIAL TISSUES: TOOTH PULP FIBERS ARE ABSENT IN  

E-print Network

ARE ABSENT IN trkA KNOCKOUT MICE S. MATSUO,a * H. ICHIKAWA,b T. A. HENDERSON,a I. SILOS-SANTIAGO,c M in the palate. In the vibrissal follicle, however, some mecha- noreceptive a¡erents were sensitive for trkA gene neurons in culture (Bradshaw et al., 1993; Levi-Montalcini, 1987). In vivo studies have also shown

Steinbach, Joe Henry

311

Pro- versus anti-inflammatory cytokine profile in African children with acute oro-facial noma (cancrum oris, noma).  

PubMed

Fresh noma is a severe orofacial necrosis with an astonishingly rapid development. It is seen mainly in malnourished children less than 4 years old from developing countries. Cytokines play a central role in oral mucosal inflammation. We therefore studied the relevance of circulating cytokines to noma, and the key microorganisms associated with the lesion. Nigerian village children with acute noma (n=68) and their neighborhood village (n=63) as well as urban (n=45) counterparts of comparable age and free of overt infections were evaluated for serum cytokine levels by ELISA. Oral bacteria were studied by polymerase chain reaction. Evaluation of random cases of the village and noma children showed marked depletion (p<0.05 or 0.001) of the plasma antioxidant micronutrients (retinol, ascorbic acid, zinc) as well as albumin and blood hemoglobin in the latter, relative to the former group. Concentrations of the circulating, pro-inflammatory cytokines (IL-18, IL-6, IL-12, IL-8, IFN-gamma) and the soluble inhibitors (TNFR-p55, TNFR-p75 and IL-1ra) were significantly higher (p<0.01 or 0.001) in noma children than in the healthy urban children, but less so when compared to their neighborhood village counterparts. The increase in levels of the anti-inflammatory/regulatory cytokines (IL-4, IL-10 and TGF-beta) was less marked relative to the pro-inflammatory cytokines. Bacteria observed at the highest frequencies in noma lesions were P. intermedia (83%), T. forsythensis (83%), P. gingivalis (50%), C. rectus (50%) and T. denticola (50%). We conclude that noma is an immunopathological response to potent bacterial factors resulting in uncontrolled production of cytokines and possibly other, still unknown, inflammatory mediators. PMID:15809209

Phillips, Reshma S; Enwonwu, Cyril O; Falkler, William A

2005-01-01

312

Intra-oral Mouth-Guard In Sport Related Oro-Facial Injuries: Prevention is Better Than Cure!  

PubMed Central

India is rapidly assuming a more health-conscious posture. Olympic competition and professional sports have turned from mere dreams into goals. Many major professional sports leagues are expanding. Sports dentistry is a composite of skills for treatment, prevention, education and research in which dentistry and sports come together. Custom athletic mouth guards present additional health-care opportunities. They are designed to reduce the impact force of a direct blow to the jaw and create a gap between the condyle and skull thereby reducing the transference of the impact to the brain. The prevalence and severity of injuries to the teeth, jaws and intra-oral and peri-oral soft tissues, concussions and neck injuries are reduced when mouth guards are used. The dentist can play a proactive role in helping to deliver important expanded health care services. PMID:24596803

Mantri, Sneha S.; Mantri, Shivkumar P.; Deogade, Suryakant; Bhasin, Abhilasha S.

2014-01-01

313

CHILES Con Pol: Probing galaxy evolution, the dark Universe, and cosmic magnetism with a deep 1000 hour Jansky VLA survey  

NASA Astrophysics Data System (ADS)

We recently started a 1000 hour campaign to observe 0.2 square degrees of the COSMOS field in full polarization continuum at 1.4 GHz with the Jansky VLA, as part of a joint program with the spectral line COSMOS HI Large Extragalactic Survey (CHILES). When complete, we expect our CHILES Continuum Polarization (CHILES Con Pol) survey to reach an unprecedented SKA-era sensitivity of 0.7 uJy per 4 arcsecond FWHM beam. Here we present the key goals of CHILES Con Pol, which are to (i) produce a source catalog of legacy value to the astronomical community, (ii) measure differential source counts in total intensity, linear polarization, and circular polarization in order to constrain the redshift and luminosity distributions of source populations, (iii) perform a novel weak lensing study using radio polarization as an indicator of intrinsic alignment to better study dark energy and dark matter, and (iv) probe the unknown origin of cosmic magnetism by measuring the strength and structure of intergalactic magnetic fields in the filaments of large scale structure. The CHILES Con Pol source catalog will be a useful resource for upcoming wide-field surveys by acting as a training set for machine learning algorithms, which can then be used to identify and classify radio sources in regions lacking deep multiwavelength coverage.

Hales, Christopher A.; Chiles Con Pol Collaboration

2014-04-01

314

Integrated Concentration in Science (iCons): Undergraduate Education Through Interdisciplinary, Team-Based, Real-World Problem Solving  

NASA Astrophysics Data System (ADS)

Attitude, Skills, Knowledge (ASK) -- In this order, these are fundamental characteristics of scientific innovators. Through first-hand practice in using science to unpack and solve complex real-world problems, students can become self-motivated scientific leaders. This presentation describes the pedagogy of a recently developed interdisciplinary undergraduate science education program at the University of Massachusetts Amherst focused on addressing global challenges with scientific solutions. Integrated Concentration in Science (iCons) is an overarching concentration program that supplements the curricula provided within each student's chosen major. iCons is a platform for students to perform student-led research in interdisciplinary collaborative teams. With a schedule of one course per year over four years, the cohort of students move through case studies, analysis of real-world problems, development of potential solutions, integrative communication, laboratory practice, and capstone research projects. In this presentation, a track emphasizing renewable energy science is used to illustrate the iCons pedagogical methods. This includes discussion of a third-year laboratory course in renewable energy that is educationally scaffolded: beginning with a boot camp in laboratory techniques and culminating with student-designed research projects. Among other objectives, this course emphasizes the practice of using reflection and redesign, as a means of generating better solutions and embedding learning for the long term.

Tuominen, Mark

2013-03-01

315

Desarrollo de la Escala sobre el Estigma Relacionado con el VIH/SIDA para Profesionales de la Salud mediante el uso de métodos mixtos123  

PubMed Central

El estigma relacionado con el VIH/SIDA continúa siendo un obstáculo para la prevención primaria y secundaria del VIH. Las consecuencias para las personas que viven con la enfermedad han sido muy documentadas y continúan siendo una gran preocupación para las personas que proveen servicios de salud y para aquellas que investigan el tema. Estas consecuencias son preocupantes cuando el estigma emana de profesionales de la salud porque se puede limitar el acceso a los servicios. Uno de los principales obstáculos para la investigación del estigma relacionado con el VIH en Puerto Rico es la falta de instrumentos cuantitativos para evaluar las manifestaciones del estigma entre profesionales de la salud. El objetivo principal de este estudio fue desarrollar y probar las propiedades psicométricas de una escala sobre el estigma relacionado con el VIH/SIDA culturalmente apropiada para personas que proveen servicios de salud puertorriqueñas y desarrollar una versión corta de la escala que pudiera usarse en escenarios clínicos con tiempo limitado. El instrumento desarrollado estuvo basado en evidencia cualitativa recopilada entre profesionales y estudiantes de profesiones de la salud puertorriqueños/as (n=80) y administrado a una muestra de 421 profesionales de la salud en adiestramiento. La escala contenía 12 dimensiones del estigma relacionado con el VIH/SIDA. El análisis cuantitativo corroboró 11 de ellas, teniendo como resultado un instrumento con validez y confiabilidad satisfactoria. Estas dimensiones, a su vez, fueron subcomponentes de un factor de estigma general superior. PMID:20333258

Varas-Díaz, Nelson; Neilands, Torsten B.; Guilamo-Ramos, Vincent; Cintrón Bou, Francheska N.

2009-01-01

316

The role of the 2H4 molecule in the generation of suppressor function in Con A-activated T cells.  

PubMed

The molecular basis for the suppression generated in a concanavalin A (Con A)-activated T cell culture remains unknown. In this study, we have attempted to determine whether the 2H4 and 4B4 molecules on Con A-activated T cells play some role in the generation of suppression by such cells. We have shown that Con A-activated suppressor cells belong to the 2H4+ subset of T cells but not the 4B4+ (2H4-) subset. Con A-activated T cells exerted their optimal suppressor function on day 2 in culture, a time at which the expression of 2H4 on such cells was maximal and 4B4 was minimal. Furthermore, the stimulation of T cells with the higher concentration of Con A generated the stronger suppressor function. At the same time, both 2H4 expression and density were increased and 4B4 expression and density were decreased on such Con A-activated T cells. More importantly, the treatment of Con A-activated T cells with anti-2H4 antibody but not with anti-4B4, anti-TQ1, or anti-T4 antibodies can block the suppressor function of such cells. Taken together, the above results strongly suggest that the 2H4 molecule itself may be involved in the generation of suppressor function in Con A-activated T cells. The 2H4 antigen on such cells was shown to be comprised of 220,000 and 200,000 m.w. glycoproteins. Thus this study indicates that the 220,000 and 200,000 m.w. structure of the 2H4 molecule may itself play a crucial role in the generation of suppressor signals of Con A-activated cells. PMID:2945865

Morimoto, C; Letvin, N L; Rudd, C E; Hagan, M; Takeuchi, T; Schlossman, S F

1986-11-15

317

Fuentes de variabilidad en el diagnóstico de gastritis atrófica multifocal asociada con la infección por Helicobacter pylori1  

PubMed Central

RESUMEN Introducción El mapeo de las diferentes regiones del estómago y el número de fragmentos de mucosa gástrica disponibles para evaluación histopatológica son fuentes importantes de variación en el momento de clasificar y hacer la gradación de la gastritis crónica. Objetivos Estimar la sensibilidad del número de fragmentos de mucosa gástrica necesarios para establecer los diagnósticos de gastritis atrófica con metaplasia intestinal (MI), displasia y estado de infección por Helicobacter pylori. Además evaluar la variabilidad intra-observador en la clasificación de estas lesiones precursoras del cáncer gástrico. Materiales y métodos En una cohorte de 6 años de seguimiento se evaluaron 1,958 procedimientos de endoscopia realizados por dos gastroenterólogos. En cada procedimiento y de cada participante se obtuvieron 5 biopsias de mucosa gástrica que representaban antro, incisura angularis y cuerpo. Un único patólogo hizo la interpretación histológica de las 5 biopsias y proporcionó un diagnóstico definitivo global que se utilizó como patrón de referencia. Cada fragmento de mucosa gástrica examinado condujo a un diagnóstico individual para cada biopsia que se comparó con el patrón de referencia. La variabilidad intra-observador se evaluó en 127 personas que corresponden a una muestra aleatoria de 20% del total de endoscopias hechas a los 72 meses de seguimiento. Resultados La sensibilidad del diagnóstico de MI y displasia gástrica aumentó de manera significativa con el número de fragmentos de mucosa gástrica evaluados El sitio anatómico de mayor sensibilidad para el diagnóstico de MI y displasia fue la incisura angularis. Para descubrir H. pylori se logró alta sensibilidad con el estudio de un solo fragmento de mucosa gástrica (95.9%) y fue independiente del sitio de obtención de la biopsia. El acuerdo intra-observador para el diagnóstico de gastritis crónica fue 86.1% con valor kappa de 0.79 IC 95% (0.76-0.85). Las biopsias fijadas en alcohol fueron inadecuadas para demostrar H. pylori e interpretar los cambios de displasia. Conclusión El número de fragmentos de mucosa gástrica evaluados, el método de fijación y la región del estómago donde se obtienen las biopsias son factores muy importantes para lograr una correcta clasificación de la gastritis crónica atrófica multifocal. PMID:25267864

Bravo, Luis Eduardo; Bravo, Juan Carlos; Realpe, José Luis; Zarama, Guillermo; Piazuelo, MarÍa Blanca; Correa, Pelayo

2014-01-01

318

DIA HORA AULA CURSO TITULACION ASIGNATURA 13/12/2013 9:00 Ningn Matriculado 1 Comn con II+LADE Introduccin a la Programacin  

E-print Network

Matemáticas 16/12/2013 15:00 Seminario 270 Departamental II 2 Común con II+LADE Fundamentos de Redes de+LADE Introducción a la Programación 18/12/2013 9:00 Ningún Matriculado 1 Común con II+LADE Fundamentos de los:00 Ningún Matriculado 1 Común con II+LADE Fundamentos Físicos de la Informática 09/01/2014 18:00 Ningún

Rey Juan Carlos, Universidad

319

iCons 2 Renewable Energy [NatSci 290IH (2) aka i2e] Spring 2013 Syllabus i2e Faculty Guides  

E-print Network

1 iCons 2 Renewable Energy [NatSci 290IH (2) aka i2e] ­ Spring 2013 Syllabus i2e Faculty Guides Objectives: Students learn to ... in the context of Renewable Energy problems. 1. ... write effectively

Auerbach, Scott M.

320

hI-con1, a factor VII-IgGFc chimeric protein targeting tissue factor for immunotherapy of uterine serous papillary carcinoma  

Microsoft Academic Search

BACKGROUND:Uterine serous papillary adenocarcinoma (USPC) is a highly aggressive variant of endometrial cancer. Human immuno- conjugate molecule (hI-con1) is an antibody-like molecule targeted against tissue factor (TF), composed of two human Factor VII (fVII) as the targeting domain, fused to human immunoglobulin (Ig) G1 Fc as an effector domain. We evaluated hI-con1 potential activity against primary chemotherapy-resistant USPC cell lines

E Cocco; Z Hu; C E Richter; S Bellone; F Casagrande; M Bellone; P Todeschini; G Krikun; D-A Silasi; M Azodi; P E Schwartz; T J Rutherford; N Buza; S Pecorelli; C J Lockwood; A D Santin

2010-01-01

321

Assessment of Response to Lithium Maintenance Treatment in Bipolar Disorder: A Consortium on Lithium Genetics (ConLiGen) Report  

PubMed Central

Objective The assessment of response to lithium maintenance treatment in bipolar disorder (BD) is complicated by variable length of treatment, unpredictable clinical course, and often inconsistent compliance. Prospective and retrospective methods of assessment of lithium response have been proposed in the literature. In this study we report the key phenotypic measures of the “Retrospective Criteria of Long-Term Treatment Response in Research Subjects with Bipolar Disorder” scale currently used in the Consortium on Lithium Genetics (ConLiGen) study. Materials and Methods Twenty-nine ConLiGen sites took part in a two-stage case-vignette rating procedure to examine inter-rater agreement [Kappa (?)] and reliability [intra-class correlation coefficient (ICC)] of lithium response. Annotated first-round vignettes and rating guidelines were circulated to expert research clinicians for training purposes between the two stages. Further, we analyzed the distributional properties of the treatment response scores available for 1,308 patients using mixture modeling. Results Substantial and moderate agreement was shown across sites in the first and second sets of vignettes (??=?0.66 and ??=?0.54, respectively), without significant improvement from training. However, definition of response using the A score as a quantitative trait and selecting cases with B criteria of 4 or less showed an improvement between the two stages (ICC1?=?0.71 and ICC2?=?0.75, respectively). Mixture modeling of score distribution indicated three subpopulations (full responders, partial responders, non responders). Conclusions We identified two definitions of lithium response, one dichotomous and the other continuous, with moderate to substantial inter-rater agreement and reliability. Accurate phenotypic measurement of lithium response is crucial for the ongoing ConLiGen pharmacogenomic study. PMID:23840348

Manchia, Mirko; Adli, Mazda; Akula, Nirmala; Ardau, Raffaella; Aubry, Jean-Michel; Backlund, Lena; Banzato, Claudio EM.; Baune, Bernhard T.; Bellivier, Frank; Bengesser, Susanne; Biernacka, Joanna M.; Brichant-Petitjean, Clara; Bui, Elise; Calkin, Cynthia V.; Cheng, Andrew Tai Ann; Chillotti, Caterina; Cichon, Sven; Clark, Scott; Czerski, Piotr M.; Dantas, Clarissa; Zompo, Maria Del; DePaulo, J. Raymond; Detera-Wadleigh, Sevilla D.; Etain, Bruno; Falkai, Peter; Frisén, Louise; Frye, Mark A.; Fullerton, Jan; Gard, Sébastien; Garnham, Julie; Goes, Fernando S.; Grof, Paul; Gruber, Oliver; Hashimoto, Ryota; Hauser, Joanna; Heilbronner, Urs; Hoban, Rebecca; Hou, Liping; Jamain, Stéphane; Kahn, Jean-Pierre; Kassem, Layla; Kato, Tadafumi; Kelsoe, John R.; Kittel-Schneider, Sarah; Kliwicki, Sebastian; Kuo, Po-Hsiu; Kusumi, Ichiro; Laje, Gonzalo; Lavebratt, Catharina; Leboyer, Marion; Leckband, Susan G.; López Jaramillo, Carlos A.; Maj, Mario; Malafosse, Alain; Martinsson, Lina; Masui, Takuya; Mitchell, Philip B.; Mondimore, Frank; Monteleone, Palmiero; Nallet, Audrey; Neuner, Maria; Novák, Tomás; O’Donovan, Claire; Ösby, Urban; Ozaki, Norio; Perlis, Roy H.; Pfennig, Andrea; Potash, James B.; Reich-Erkelenz, Daniela; Reif, Andreas; Reininghaus, Eva; Richardson, Sara; Rouleau, Guy A.; Rybakowski, Janusz K.; Schalling, Martin; Schofield, Peter R.; Schubert, Oliver K.; Schweizer, Barbara; Seemüller, Florian; Grigoroiu-Serbanescu, Maria; Severino, Giovanni; Seymour, Lisa R.; Slaney, Claire; Smoller, Jordan W.; Squassina, Alessio; Stamm, Thomas; Steele, Jo; Stopkova, Pavla; Tighe, Sarah K.; Tortorella, Alfonso; Turecki, Gustavo; Wray, Naomi R.; Wright, Adam; Zandi, Peter P.; Zilles, David; Bauer, Michael; Rietschel, Marcella; McMahon, Francis J.

2013-01-01

322

pH-sensitive C-ON bond homolysis of alkoxyamines of imidazoline series: a theoretical study.  

PubMed

The pH-dependent kinetics of C-ON bond homolysis reactions of the four alkoxyamines (viz., the derivatives of 2-(4-(dimethylamino)-2-ethyl-5,5-dimethyl-2-(pyridin-4-yl)-2,5-dihydro-1H-imidazol-1-oxyl and 2-(2-carboxyethyl)-5,5-diethyl-2,4-dimethyl-2,5-dihydro-1H-imidazol-1-oxyl) in water solution have been scrutinized using DFT calculations (M06-2X/6-311++G(2df,p) level of theory with the PCM model). On the basis of computations, the experimental results obtained before (J. Org. Chem. 2011, 76, 5558) have been rationalized. The concentration dependence of all possible protonated forms of the four alkoxyamines was obtained from pH measurements. The contributions of particular protonated forms into the overall rate constants of thermolysis were estimated using the DFT calculated Gibbs free energies ?(r)?G of C-ON bond homolysis reactions. The computations revealed that the observed rate constants of thermolysis of the two species at several pH values are dominated by decomposition reactions of two or even three protonated forms. The observed trends in reactivity of the alkoxyamines were mainly attributed to destabilization of the radical products of C-ON bond scission reactions. A linear correlation between the sum of radical stabilization energies (RSEs) of products of thermolysis and the calculated Gibbs free energies of reactions was found for various protonated forms of the species studied. Apart from this, the linear correlation exists between the relative RSE and nitrogen hyperfine constants aN of various protonated forms of the nitroxide radical products. PMID:24804900

Parkhomenko, Dmitriy A; Edeleva, Mariya V; Kiselev, Vitaly G; Bagryanskaya, Elena G

2014-05-22

323

CONS-COCOMAPS: a novel tool to measure and visualize the conservation of inter-residue contacts in multiple docking solutions  

PubMed Central

Background The development of accurate protein-protein docking programs is making this kind of simulations an effective tool to predict the 3D structure and the surface of interaction between the molecular partners in macromolecular complexes. However, correctly scoring multiple docking solutions is still an open problem. As a consequence, the accurate and tedious screening of many docking models is usually required in the analysis step. Methods All the programs under CONS-COCOMAPS have been written in python, taking advantage of python libraries such as SciPy and Matplotlib. CONS-COCOMAPS is freely available as a web tool at the URL: http://www.molnac.unisa.it/BioTools/conscocomaps/. Results Here we presented CONS-COCOMAPS, a novel tool to easily measure and visualize the consensus in multiple docking solutions. CONS-COCOMAPS uses the conservation of inter-residue contacts as an estimate of the similarity between different docking solutions. To visualize the conservation, CONS-COCOMAPS uses intermolecular contact maps. Conclusions The application of CONS-COCOMAPS to test-cases taken from recent CAPRI rounds has shown that it is very efficient in highlighting even a very weak consensus that often is biologically meaningful. PMID:22536965

2012-01-01

324

Pros and Cons of Using Arrays of Small Antennas Versus Large Single Dish Antennas for the Deep Space Network  

NASA Technical Reports Server (NTRS)

This paper briefly describes pros and cons of using arrays of small antennas instead of large single dish antennas for spacecraft telemetry, command, and tracking (TT and C) - communications and navigation (C and N) - and science support that the Deep Space Network (DSN) normally provides. It considers functionality and performance aspects, mainly for TT and C, though it also considers science. It only briefly comments on the cost aspects that seem to favor arrays of small antennas over large single antennas, at least for receiving (downlinks).

Bagri, Durgadas S.

2009-01-01

325

Modelo de accesibilidad de conceptos matematicos aplicados en el curso de Astronomia Descriptiva para estudiantes con impedimentos visuales en la UPR  

NASA Astrophysics Data System (ADS)

Este estudio utiliza metodologia de investigacion cualitativa, con el proposito de describir, analizar y evaluar los procesos de diseno y desarrollo de un modelo de accesibilidad que consiste en estrategias de ensenanza de las matematicas para estudiantes con impedimentos visuales matriculados en el curso de Astronomia Descriptiva en la UPR. Se utilizaron las siguientes estrategias para recopilar la informacion, 1) reflexiones de la investigadora en el proceso de diseno y desarrollo de las lecciones adaptadas, que se registraron en un diario reflexivo. 2) entrevista semiestructurada luego de haber trabajado las lecciones de aprendizaje adaptadas con los participantes. 3) observaciones y notas de la investigadora del trabajo de los participantes. Para obtener la informacion de los participantes se obtuvo los permisos institucionales necesarios; se seleccionaron los participantes y se validaron los instrumentos; se realizo el desarrollo de las lecciones adaptadas con los participantes; y finalmente, se analizo la informacion obtenida. El diseno de las lecciones de aprendizaje adaptadas se hizo siguiendo las recomendaciones curriculares de los temas de matematicas aplicados en el curso de Astronomia Descriptiva realizado por la investigadora durante su semestre de internado. El testimonio de las voces de los participantes se obtuvo del proceso de desarrollo de las lecciones de aprendizaje adaptadas de temas seleccionados de conceptos matematicos requeridos en el curso de Astronomia Descriptiva y de la entrevista semiestructurada con los participantes, luego de haber trabajado las lecciones de aprendizaje. Para el desarrollo de las lecciones de aprendizaje, se utilizaron materiales tactiles adaptados, materiales tactiles disenados y materiales disponibles comercialmente. Los textos de las lecciones se imprimieron en tinta y en Braille. Se exhorta a disenar y desarrollar estrategias de ensenanza accesibles, considerando como recursos para evaluar su efectividad a personas con impedimentos visuales. El utilizar estrategias de aprendizaje accesibles de acuerdo a las necesidades individuales de los estudiantes, contribuye para que los estudiantes con impedimentos visuales descubran, exploren, investiguen y formulen sus propias conclusiones durante su proceso de aprendizaje.

Isidro Villamizar, Gloria Maria

326

ON EFFECT OF HAZARD MAP ON CONS CIOUSNESS OF FLOOD DISASTER PREVENSION OF RESIDENTS WHO EXPERIENCED FLOOD RECENTLY  

NASA Astrophysics Data System (ADS)

In this paper, the effect of the flood hazard map distributed to the residents who experienced flood disasters recently and an effective method for improving consciousness of flood di saster prevention are discussed. The questionnaire surveys were conducted on the residents living in the middle basin of the Nishiki River, Iwakuni city, Yamaguchi Prefecture, before and after the distribution of the hazard map. It is found from this investigation that "knowledge", "att achment", and "crisis", are the main factors in the psychological process related to the flood prevention behavior. The effect of the distribution of the hazard map is judged from the probability of the flood prevention behavior. In addition, it is also found that "knowledge", "flood experiment of T0514", "crisis", "eff ectiveness", "load", and "easy reading of the hazard map", are keys to improve the cons ciousness of flood di saster prevention.

Asai, Koji; Koga, Syota; Sakakibara, Hiroyuki

327

Intraspecific alkaloid variation in ladybird eggs and its effects on con- and hetero-specific intraguild predators.  

PubMed

Egg predation and cannibalism are common phenomena in predatory ladybirds despite the presence of defensive alkaloids. Consumption of heterospecific eggs negatively affects survivorship and development; however, intraspecific variation in quantities of alkaloids and post-ingestion responses to con- and hetero-specific alkaloids, are not well understood. We examined variation in the quantity of alkaloids in eggs of Harmonia axyridis (Pallas), Coccinella septempunctata L., and Hippodamia convergens (Guérin) using gas chromatography-mass spectrometry, and show a link between heterospecific alkaloids and their toxicity and/or costs by feeding high and low alkaloid eggs to first instar H. axyridis and C. septempunctata. The repeatability of alkaloid measurements in eggs in an egg cluster was high; however, the amount of alkaloids varied significantly between egg clutches within and among females. This variation affected egg consumption by C. septempunctata when fed H. axyridis eggs. Harmonia axyridis accumulated their own alkaloid by cannibalism and synthesized it de novo, but C. septempunctata lost some portion of the consumed conspecific alkaloids. Both species lost most of the consumed heterospecific alkaloids, but C. septempunctata died within 3 days. Most H. axyridis survived to the second instar, but C. septempunctata alkaloids led to a significant reduction in weight gain compared to an aphid control. In addition, ingestion of high alkaloid C. septempunctata extended development of H. axyridis compared to the aphid control or conspecific eggs. Harmonia axyridis had greater abilities to process ingested con- and hetero-specific alkaloids compared with C. septempunctata, which may, in part, explain their interspecific interactions in nature. PMID:20049478

Kajita, Yukie; Obrycki, J J; Sloggett, J J; Haynes, K F

2010-06-01

328

Inversor Resonante de Tres Elementos L-LC con Caracteristica Cortocircuitable para Aplicaciones de Calentamiento por Induccion  

NASA Astrophysics Data System (ADS)

Los generadores de calentamiento por induccion son puentes inversores con carga resonante, cuya mision es basicamente crear una corriente sinusoidal de gran amplitud sobre la "bobina de caldeo", que forma parte del tanque resonante. En el interior de esta bobina se introduce la pieza que se desea calentar. EI campo magnetico creado induce corrientes superficiales (corrientes de Foucault) sobre la pieza, que producen su calentamiento. Los tanques resonantes (tambien llamados osciladores) utilizados en la actualidad son el resonante serie y el resonante paralelo. Aunque ya desde hace algun tiempo se vienen construyendo generadores de alta potencia basados en estos dos osciladores, el exito nunca ha. sido completo en ninguno de los dos casos. Tal y como se explica en la introduccion de esta memoria, los puentes inversores utilizados deben operar sobre una carga inductiva (corriente retrasada) para evitar el fenomeno de la recuperacion inversa de sus diodos y la consiguiente ruptura de los transistores. De la restriccion topologica anterior se deduce que el generador paralelo debe conmutar a frecuencias inferiores a la resonancia, y el serie a frecuencias superiores. A esta restriccion topologica hay que unir otra que es exclusiva del calentamiento por induccion: La corriente por la bobina de caldeo debe ser sinusoidal. De no ser asi, resultaria imposible disponer toda la potencia de calentamiento sobre la pieza en el espesor requerido por la aplicacion. Como consecuencia, los inversores no pueden operar por debajo de la frecuencia de resonancia del oscilador, pues en ese caso se amplifican los armonicos de orden superior de la tension/corriente de entrada situados sobre la resonancia, con la consiguiente distorsion de la corriente de salida. La conjuncion de las dos restricciones anteriores obligan al inversor paralelo a funcionar a la frecuencia de resonancia del oscilador. Esto imposibilita un control por variacion de frecuencia, regulandose la potencia desde la seccion de entrada mediante un mayor o menor aporte de corriente al puente. Como consecuencia, la seccion de entrada del paralelo, ya de por si mas voluminosa que lao del serie por el uso de grandes componentes magneticos (bobinas de filtro o de "alisamiento"), result a tambien mas complicada y costosa debido a la necesidad de ser implementada mediante rectificador controlado. Ademas, la regulacion que ofrece el rectificador es pobre, dada su baja frecuencia de conmutacion. En cambio, el circuito serie puede funcionar por encima de la resonancia manteniendo una secuencia de conmutacion sin riesgos de recuperacion inversa y con una corriente de salida practicamente sinusoidal, lo que permite un control de la potencia por variacion de frecuencia. Puesto que la tarea de regulacion se realiza desde el puente inversor, la regulacion resulta mucho mas eficaz y la seccion de entrada se puede implementar mediante un simple rectificador no controlado y un condensador de filtro. (Abstract shortened by UMI.).

Espi Huerta, Jose Miguel

329

AC 2011-376: WIRELESS-INTEGRATED EMBEDDED REAL-TIME CON-TROL: A CASE STUDY IN ADOPTING RESOURCES FOR DEVELOP-  

E-print Network

in areas of control and embedded systems that weaves critical aspects of control systems design with real-timeAC 2011-376: WIRELESS-INTEGRATED EMBEDDED REAL-TIME CON- TROL: A CASE STUDY IN ADOPTING RESOURCES of Engineering. cAmerican Society for Engineering Education, 2011 #12;Wireless-Integrated Embedded Real-Time

330

INTERNATIONAL SERIES IN PURE AND APPLIED PHYSICS LEO N A R D 1. S CHI F F, CON S U L TIN G E D ITO R  

E-print Network

INTERNATIONAL SERIES IN PURE AND APPLIED PHYSICS LEO N A R D 1. S CHI F F, CON S U L TIN G E D ITO of Gases Read Dislocations in Crystals Richtmyer, Kennard, and Lauritsen Introduction to Modern Physics Quantum Theory of Matter Slater Quantum Theory of Atomic Structure, Vol. I Slater Quantum Theory of Atomic

Allen, Jont

331

IEEE TRANSACTIONS ON AUTOMATIC CONTROL, VOL. 57, NO. 10, OCTOBER 2012 2633 [10] G. Tao, X. Ma, and Y. Ling, "Optimal and nonlinear decoupling con-  

E-print Network

. Cha Abstract--A limitation of the original gain-scheduling approaches is that the closed. Huang, "Adaptive wavelet neural network con- trol with hysteresis estimation for piezo-positioning mechanism," IEEE Trans. Neural Netw., vol. 17, no. 2, pp. 432­444, 2006. Simplified Rapid Switching Gain

Rotkowitz, Michael C.

332

CITRIS Workshop on Power Engineering and the Smart Grid The November 22, 2013 CITRIS Workshop on Power Engineering and the Smart Grid con-  

E-print Network

Report CITRIS Workshop on Power Engineering and the Smart Grid The November 22, 2013 CITRIS Workshop on Power Engineering and the Smart Grid con- sidered the intellectual content of, and some first multidisciplinary. 1 #12;· As automatic control mechanisms become more fundamental to grid operation, security

Yoo, S. J. Ben

333

Determinación de la aptitud de uso del suelo para producción de cultivos con fines bioenergéticos en la provincia de Salta (Noroeste Argentino)  

Microsoft Academic Search

RESUMEN El presente trabajo presenta los resultados alcanzados en la determinación de la aptitud de uso del suelo para producción de cultivos con fines bioenergéticos en la provincia de Salta (Argentina). Para este propósito se buscó aunar los criterios de sustentabilidad social, económica, energética y ambiental que definen el desarrollo sostenible de los sistemas bioenergéticos. El objetivo principal del trabajo

Renée Alicia Anschau; María Cad; Stella Carballo; Noelia Flores

2011-01-01

334

Kurt J. Koester To obtain a position that allows me to use my skills and knowledge in materials science to con-  

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in materials science to con- duct research and develop new products and technologies. EDUCATION: 2003-2007 University of California, Berkeley Berkeley, CA Doctor of Philosophy, Engineering, Materials Science and Engineering Minors: Bioengineering and Business Administration Master of Engineering, Materials Science

Ritchie, Robert

335

La Meccanica Quantistica e una teoria completa? e quale relazione ha con la Teoria della Relativita? certo sono di#cilmente compatibili come testimoniano i  

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Prefazione La Meccanica Quantistica â??e una teoria completa? e quale relazione ha con la Teoria alternativi di fonderle e il grandioso tentativo in atto di formulare una teoria delle stringhe. Questi sono Quantica: non tocca la teoria quantistica dei campi che ha raggiunto il massimo sviluppo dopo gli anni '30

Roma "La Sapienza", Università di

336

Actividades en el mbito de la internacionalizacin y de la movilidad universitaria Continuando con el propsito de fortalecer el grado de internacionalidad de la UIB y de  

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Actividades en el ámbito de la internacionalización y de la movilidad universitaria Continuando con programas de movilidad de estudiantes existentes como a iniciar nuevos, al mismo tiempo que se han puesto en marcha las correspondientes convocatorias de movilidad para profesores y personal de administración y

Oro, Daniel

337

Tutores/as Acadmicos/as de Movilidad El Vicedecanato de Relaciones Internacionales y Movilidad (VRIM) cuenta con una red de tutores/as de movilidad  

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Tutores/as Académicos/as de Movilidad El Vicedecanato de Relaciones Internacionales y Movilidad (VRIM) cuenta con una red de tutores/as de movilidad cuyas funciones son: Asesorar a los/as estudiantes (tanto propios como acogidos) en la elección de asignaturas que cursarán durante su periodo de movilidad

Escolano, Francisco

338

AbstractThe Kern River Gas Transmission pipeline was con-structed in 1991 to supply natural gas to be used in the thermally  

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94 Abstract­The Kern River Gas Transmission pipeline was con- structed in 1991 to supply natural plants were found in the 11 seeded plots. The Kern River Gas Transmission pipeline (KRGT) was constructed California. The pipeline route extended from a point near Opal, Wyoming, through Utah and Nevada to Daggett

339

Transformacin del campus para el desarrollo de un modelo social integral y su interaccin con el entorno territorial Tabla I. Descripcin de las actuaciones del proyecto  

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, promociones entre los estudiantes y presencia activa en los actos de graduación, newsletters, redes sociales yTransformación del campus para el desarrollo de un modelo social integral y su interacción con el colectivo de referencia en los ámbitos de ciencias sociales, de la comunicación y de la biomedicina

Geffner, Hector

340

proceedings: Conscmation. Restoraton. and Management ol Tonoises and Tunles-An Intemauonal ConJerence, pp. 383-391 @ 1987 by thc New York Tunlc and Tonorse Society  

E-print Network

Turtle Nesting Areas for Protection and Management fucHeno R. BugcH,l Lnwu-e G. HetsoN,2 AND Menr DRact: The wood turtle, Clemmys insculpta,is a long-lived, semi-aquatic, riverine species that inhabits forcsted list the wood turtle as "Endangered" or "Threatenedr" and it is now listed on Appendix tr of the Con

341

Synthesis of water-soluble Ag?Se QDs as a novel resonance Rayleigh scattering sensor for highly sensitive and selective ConA detection.  

PubMed

Ag2Se quantum dots (QDs) have attracted a lot of interest due to their potential applications in biosensing and bioimaging. A strategy is presented that involves coupling of selenium powder reduction with the binding of silver ions, and thioglycollic acid (TGA) and glycine as stabilizers to obtain ultrasmall Ag2Se QDs at 85 °C in aqueous solution. This strategy avoids high temperatures, high pressures and organic solvents so that water-soluble 3 nm Ag2Se QDs can be directly obtained. The conjugation of ConA to TGA stabilized Ag2Se QDs by hydrogen bonds leads to the adsorption of ConA to Ag2Se QDs and forms the aggregation and leads to the generation of resonance Rayleigh scattering (RRS) as a readout signal for the sensing events. The reaction mechanism of Ag2Se QD RRS enhancement is studied in this work. The resulting RRS sensor enables the detection of ConA with limit of detection reaching 0.08 ?g mL(-1) concentration in a wide linear range from 0.27 ?g mL(-1) to 35 ?g mL(-1). The recovery of spiked ConA in human serum samples ranges from 94% to 106%. The relative standard deviation (RSD) for eleven replicate detections is 3.6%. Our results correlate many important experimental observations and will fuel the further growth of this field. PMID:24957549

Yan, Shuguang; Zhang, Lichun; Tang, Yurong; Lv, Yi

2014-09-01

342

""This talk explains how the con uence of cloud computing and Massive OpenOnline Courses (MOOCs) have allowed us greatly  

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""This talk explains how the con uence of cloud computing and Massive OpenOnline Courses (MOOCs explains how the confluence of cloud computing and Massive Open Online Courses (MOOCs) have allowed us software engineering course. Colloquium and Distinguished LECTURE SERIES Myths About MOOCs and Software

Zhou, Yuanyuan

343

474 The american biology Teacher volume 73, no. 8, ocTober 2011 The accumulation of plastic in the oceans is an ever-growing environmental con-  

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of plastic in the oceans is an ever-growing environmental con- cern. Plastic debris is a choking debris. Key Words: Ocean pollution; toxicology; ecosystem health; ocean literacy; envi- ronmental science of plastic pollution. They can be modified to be appro- priate for grades 6­10. Oikonos Ecosystem Knowledge

Schladow, S. Geoffrey

344

AVISO EN CONTRA DE ACTOS DISCRIMINATORIOS De conformidad con la Ley de Derechos Humanos del Distrito de Columbia (D.C.) de 1977, segn enmendada,  

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AVISO EN CONTRA DE ACTOS DISCRIMINATORIOS De conformidad con la Ley de Derechos Humanos del a medidas disciplinarias. La Ley de Derechos Humanos del Distrito de Columbia (D.C.), Sección 2-1402.31(a discriminar: "Negarle a una persona, de forma directa o indirecta, el derecho a disfrutar a plenitud y

Weaver, Harold A. "Hal"

345

Departamento de Disciplinas Econmicas y Financieras El Departamento de Disciplinas Econmicas y Financieras, con sede en la Facultad de Derecho de la Universidad  

E-print Network

Financieras, con sede en la Facultad de Derecho de la Universidad de Alicante, está compuesto por el área de conocimiento de Derecho Financiero y Tributario que centra su actividad en las facultades de Derecho, Ciencias: Estudios de 1er y 2º Ciclo (a extinguir) Licenciatura en Derecho. Licenciatura Derecho-ADE (DADE

Escolano, Francisco

346

Page 296 Courses: Economics (ECON) Sonoma State University 2013-2014 Catalog eCon 317 introduCtion to eConoMetriCS (4)  

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-sectional techniques, time series analysis, simultaneous equation modeling, and forecasting. Applying widely, or equivalents or consent of instructor. eCon 319 MAnAgeriAL eConoMiCS (4) Economic analysis applied the content and applicability of such basic economic concepts as marginality, opportunity costs, and market

Ravikumar, B.

347

To be presented at the Fourth International Workshop on Virtual Rehabilitation, Catalina Island, CA, September 2005. Usability of the Remote Console (ReCon) for Virtual Reality  

E-print Network

, September 2005. Usability of the Remote Console (ReCon) for Virtual Reality Telerehabilitation: Formative. Keywords virtual reality, telerehabilitation, physical therapy, formative evaluation, usability engineering for virtual reality telerehabilitation from a host site to a clinic or a home using real-time patient

New Jersey, University of Medicine and Dentistry of

348

arXiv:submit/0083985[cond-mat.supr-con]29Jul2010 Metastability in a nano-bridge based hysteretic DC-SQUID embedded in  

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arXiv:submit/0083985[cond-mat.supr-con]29Jul2010 Metastability in a nano-bridge based hysteretic DC-SQUID study the metastable response of a highly hysteretic DC-SQUID made of a Niobium loop interrupted by two nano-bridges. We excite the SQUID with an alternating current and with direct magnetic flux, and find

Buks, Eyal

349

ConSoil 2005 -Abstract form Title of abstract Alcohol Flushing: Parameter Estimation for a cost efficient in-situ remediation  

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alcohols from the aquifer. The removed mixture has to be sent to a treatment plant in order to separateConSoil 2005 - Abstract form Title of abstract Alcohol Flushing: Parameter Estimation for a cost.greiner@iws.uni-stuttgart.de Phone +49 - 711 / 685 4602 Fax +49 - 711 / 685 7020 Topics: Alcohol flushing, in-situ remediation

Cirpka, Olaf Arie

350

Accordo con QdG Teatro Leonardo Soc. Consortile a r.l. Stagione Teatrale 2013/2014 -www.teatroleonardo.it  

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, l'accesso al Teatro Leonardo Da Vinci per gli studenti universitari(2) con tesserino universitario e definire a cura di Teatro Leonardo da Vinci, estensibili ad uno o più accompagnatori se indicato. Per tutte dello "Studio U.r.p. "(3). (1) Storia e Informazioni su www.teatroleonardo.it Teatro Leonardo da Vinci

De Cindio, Fiorella

351

Analysis of cancer risk and BRCA1 and BRCA2 mutation prevalence in the kConFab familial breast cancer resource  

PubMed Central

Introduction The Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer (kConFab) is a multidisciplinary, collaborative framework for the investigation of familial breast cancer. Based in Australia, the primary aim of kConFab is to facilitate high-quality research by amassing a large and comprehensive resource of epidemiological and clinical data with biospecimens from individuals at high risk of breast and/or ovarian cancer, and from their close relatives. Methods Epidemiological, family history and lifestyle data, as well as biospecimens, are collected from multiple-case breast cancer families ascertained through family cancer clinics in Australia and New Zealand. We used the Tyrer-Cuzick algorithms to assess the prospective risk of breast cancer in women in the kConFab cohort who were unaffected with breast cancer at the time of enrolment in the study. Results Of kConFab's first 822 families, 518 families had multiple cases of female breast cancer alone, 239 had cases of female breast and ovarian cancer, 37 had cases of female and male breast cancer, and 14 had both ovarian cancer as well as male and female breast cancer. Data are currently held for 11,422 people and germline DNAs for 7,389. Among the 812 families with at least one germline sample collected, the mean number of germline DNA samples collected per family is nine. Of the 747 families that have undergone some form of mutation screening, 229 (31%) carry a pathogenic or splice-site mutation in BRCA1 or BRCA2. Germline DNAs and data are stored from 773 proven carriers of BRCA1 or BRCA1 mutations. kConFab's fresh tissue bank includes 253 specimens of breast or ovarian tissue – both normal and malignant – including 126 from carriers of BRCA1 or BRCA2 mutations. Conclusion These kConFab resources are available to researchers anywhere in the world, who may apply to kConFab for biospecimens and data for use in ethically approved, peer-reviewed projects. A high calculated risk from the Tyrer-Cuzick algorithms correlated closely with the subsequent occurrence of breast cancer in BRCA1 and BRCA2 mutation positive families, but this was less evident in families in which no pathogenic BRCA1 or BRCA2 mutation has been detected. PMID:16507150

Mann, Graham J; Thorne, Heather; Balleine, Rosemary L; Butow, Phyllis N; Clarke, Christine L; Edkins, Edward; Evans, Gerda M; Fereday, Sián; Haan, Eric; Gattas, Michael; Giles, Graham G; Goldblatt, Jack; Hopper, John L; Kirk, Judy; Leary, Jennifer A; Lindeman, Geoffrey; Niedermayr, Eveline; Phillips, Kelly-Anne; Picken, Sandra; Pupo, Gulietta M; Saunders, Christobel; Scott, Clare L; Spurdle, Amanda B; Suthers, Graeme; Tucker, Kathy; Chenevix-Trench, Georgia

2006-01-01

352

Status and Progress of a Fault Current Limiting Hts Cable to BE Installed in the con EDISON Grid  

NASA Astrophysics Data System (ADS)

In the last decade, significant advances in the performance of second generation (2G) high temperature superconducting wire have made it suitable for commercially viable applications such as electric power cables and fault current limiters. Currently, the U.S. Department of Homeland Security is co-funding the design, development and demonstration of an inherently fault current limiting HTS cable under the Hydra project with American Superconductor and Consolidated Edison. The cable will be approximately 300 m long and is being designed to carry 96 MVA at a distribution level voltage of 13.8 kV. The underground cable will be installed and energized in New York City. The project is led by American Superconductor teamed with Con Edison, Ultera (Southwire and nkt cables joint venture), and Air Liquide. This paper describes the general goals, design criteria, status and progress of the project. Fault current limiting has already been demonstrated in 3 m prototype cables, and test results on a 25 m three-phase cable will be presented. An overview of the concept of a fault current limiting cable and the system advantages of this unique type of cable will be described.

Maguire, J.; Folts, D.; Yuan, J.; Henderson, N.; Lindsay, D.; Knoll, D.; Rey, C.; Duckworth, R.; Gouge, M.; Wolff, Z.; Kurtz, S.

2010-04-01

353

Air Traffic Management Technology Demonstration-1 Concept of Operations (ATD-1 ConOps), Version 2.0  

NASA Technical Reports Server (NTRS)

This document is an update to the operations and procedures envisioned for NASA s Air Traffic Management (ATM) Technology Demonstration #1 (ATD-1). The ATD-1 Concept of Operations (ConOps) integrates three NASA technologies to achieve high throughput, fuel-efficient arrival operations into busy terminal airspace. They are Traffic Management Advisor with Terminal Metering (TMA-TM) for precise time-based schedules to the runway and points within the terminal area, Controller-Managed Spacing (CMS) decision support tools for terminal controllers to better manage aircraft delay using speed control, and Flight deck Interval Management (FIM) avionics and flight crew procedures to conduct airborne spacing operations. The ATD-1 concept provides de-conflicted and efficient operations of multiple arrival streams of aircraft, passing through multiple merge points, from top-of-descent (TOD) to the Final Approach Fix. These arrival streams are Optimized Profile Descents (OPDs) from en route altitude to the runway, using primarily speed control to maintain separation and schedule. The ATD-1 project is currently addressing the challenges of integrating the three technologies, and their implantation into an operational environment. The ATD-1 goals include increasing the throughput of high-density airports, reducing controller workload, increasing efficiency of arrival operations and the frequency of trajectory-based operations, and promoting aircraft ADS-B equipage.

Baxley, Brian T.; Johnson, William C.; Swenson, Harry N.; Robinson, John E.; Prevot, Tom; Callantine, Todd J.; Scardina, John; Greene, Michael

2013-01-01

354

The Classics, Con Brio  

ERIC Educational Resources Information Center

Sponsored by a consortium of 30 American universities, Rome's Intercollegiate Center for Classical Studies offers a year of study to American undergraduate classics majors. Instructors are also American and normally stay only a year; teaching assistants are always ex-students of the center. Extensive field trips are an important part of the…

Hansen, James

1978-01-01

355

EthicsConRep  

Cancer.gov

The authors also gratefully acknowledge the copy editing assistance of Leslie Alter, MPH and Steve Brown. The Ethical Force Program’s initiative on patient-centered communication is funded in part by the American Medical Association Foundation, The California Endowment, the Commonwealth Fund and the Connecticut Health Foundation.

356

Neo-Conned University  

ERIC Educational Resources Information Center

Censorship, says Australian political theorist John Keane (1991), can "echo within us, take up residence within ourselves, spying on us, a private amanuensis who reminds us never to go too far... It makes us zip our lips, tremble and think twice" (p. 39). It can also make us sick. The author states that this is her argument here: that,…

Jones, Andee

2014-01-01

357

urban ConAgraculture  

Microsoft Academic Search

Current pressures in today’s world caused me to investigate strategies of change in the organization of society to promote a more effi cient existence. Globalization, a movement characterized by the dissemination of economies, ethnicities, media, ideas, technologies, and production; has become today’s reality. The shift from imperialism to globalism has caused a decline in the power and importance of nation

Dale J Luebbert

2009-01-01

358

Verde Sport S.p.A. con il patrocinio di Assicurazioni Generali e il sostegno di Telecom Italia, bandisce un concorso per il conferimento di 6 premi del valore di 1.000 euro ciascuno a favore di laureati in  

E-print Network

e sport (www.mastersbs.it); Impiantistica sportiva (www.mastersbs.it); Doping sportivo, sia comeBIBLIOTECA STEFANO BENETTON Verde Sport S.p.A. con il patrocinio di Assicurazioni Generali e il ciascuno a favore di laureati in Università italiane con tesi su temi riguardanti lo sport o la

Guidoni, Leonardo

359

Esplorazione Della Terra Incognita Della Fisica Nucleare: Nuclei Con Alone, Nuclei "A Grappoli", Nuclei Borromeani e Altre Stranezze Esotiche!  

E-print Network

English: If the current status of theoretical and experimental knowledge in Nuclear Physics could be reduced to a geographical chart or a planisphere, then our epoch would be in some respect comparable to the end of the Medieval age and in other to the beginning of the Reinassance: epochs in which, together with the consolidated knowledge of the Old World, there have been great and revolutionary expeditions as the discovery of America or the periplus of Cape of Good Hope, explorations aimed at reaching the limits that, along the centuries, have lead to more and more engaging scientific discoveries in more and more far away lands, ending only in the twentieth century with the complete mapping of all the continents. Nuclear Physics is living an analogous adventure on the plane of contrast... - Italian: Se lo stato attuale delle conoscenze teoriche e sperimentali della Fisica Nucleare si potesse ridurre a una carta geografica o un mappamondo, allora la nostra epoca si potrebbe paragonare per certi versi alla fine del Medioevo e per altri al Rinascimento: epoche in cui, accanto alla conoscenza consolidata del Vecchio mondo, ci furono grandi e rivoluzionarie spedizioni come la scoperta dell'America o il periplo del Capo di Buona Speranza, esplorazioni geografiche volte al raggiungimento dei limiti che, nel corso dei secoli, hanno portato a scoperte scientifiche sempre pi\\`u avvincenti in terre sempre pi\\`u lontane, culminate solo nel ventesimo secolo con la completa mappatura di tutte le terre emerse. La Fisica Nucleare sta vivendo un'avventura analoga sul piano della contrapposizione tra la conoscenza acquisita sui nuclei stabili e la scoperta delle sorprendenti propriet\\`a esotiche dei nuclei instabili, pi\\`u difficili da produrre, da studiare e da comprendere.

Lorenzo Fortunato

2011-04-04

360

An inevitable wave of prescription drug monitoring programs in the context of prescription opioids: pros, cons and tensions  

PubMed Central

Background In an effort to control non-medical use and/or medical abuse of prescription drugs, particularly prescription opioids, electronic prescription drug monitoring programs (PDMP) have been introduced in North-American countries, Australia and some parts of Europe. Paradoxically, there are simultaneous pressures to increase opioid prescribing for the benefit of individual patients and to reduce it for the sake of public health, and this pressure warrants a delicate balance of appropriate therapeutic uses of these drugs with the risk of developing dependence. This article discusses pros and cons of PDMP in reducing diversion of prescription opioids, without hampering access to those medications for those with genuine needs, and highlights tensions around PDMP implementation. Discussion PDMPs may help alleviate diversion, over-prescription and fraudulent prescribing/dispensing; prompt drug treatment referrals; avoid awkward drug urine test; and inform spatial changes in prescribing practices and help designing tailored interventions. Fear of legal retribution, privacy and data security, potential confusion about addiction and pseudo-addiction, and potential undue pressure of detecting misuse/diversion - are the major problems. There are tensions about unintended consequence of excessive regulatory enforcements, corresponding collateral damages particularly about inadequate prescribing for patients with genuine needs, and mandatory consultation requirements of PDMP. Summary In this era of information technology PDMP is likely to flourish and remain with us for a long time. A clear standard of practice against which physicians’ care will be judged may expedite the utilisation of PDMP. In addition, adequate training on addiction and pain management along with public awareness, point-of-supply data entry from pharmacy, point-of-care real-time access to data, increasing access to addiction treatment and appropriate regulatory enforcement preferably through healthcare administration, together, may help remove barriers to PDMP use. PMID:25127880

2014-01-01

361

reThiNKiNG The BoUNdaries The dUKe MBa--CroSS ConTInenT  

E-print Network

reThiNKiNG The BoUNdaries The dUKe MBa--CroSS ConTInenT #12;develoP GloBal iNsiGhT The duke MBa--cross continent program is designed to help full-time working professionals earn a world- class MBa while building, The duke MBa-- cross continent program builds more than global awareness; it provides the necessary real

Dolbow, John

362

1.0 What is Statistics? 1.1 What is Mathematical Statistics? Random Data Basic Ideas in Statistics 1.2 Fundamental Con Mathematical Statistics  

E-print Network

§1.0 What is Statistics? §1.1 What is Mathematical Statistics? Random Data Basic Ideas in Statistics §1.2 Fundamental Con Mathematical Statistics Zhang, Lixin and Dai, Jialing Course Website: www.math.zju.edu.cn/zlx/teaching.htm #12;§1.0 What is Statistics? §1.1 What is Mathematical Statistics? Random Data Basic Ideas

Zhang, Li-Xin

363

Guided ion beam studies of the reactions of Con+ (n=1-18) with N2: Cobalt cluster mononitride and dinitride bond energies  

NASA Astrophysics Data System (ADS)

The reactions of Con+ (n=1-18) with N2 are measured as a function of kinetic energy over a range of 0-15eV in a guided ion beam tandem mass spectrometer. A variety of Com+, ComN+, and ComN2+ (m?n) product ions are observed, all in endothermic processes, with collision-induced dissociation dominating the products for all clusters. Bond dissociation energies for both cobalt cluster nitrides and dinitrides are derived from threshold analysis of the energy dependence of the endothermic reactions using several different approaches. These values show only a mild dependence on cluster size over the range studied, although the Co13+-N bond energy is relatively weak. The bond energies of Con+-N for larger clusters suggest that a reasonable value for the desorption energy of atomic nitrogen from bulk phase cobalt is 6.3±0.2eV, which is somewhat lower than the only available value in the literature, an estimate based on the enthalpy of formation of bulk cobalt nitride. The trends in the cobalt nitride thermochemistry are also compared to previously determined metal-metal bond energies, D0(Con+-Co), and to D0(Fen+-N). Implications for catalytic ammonia production using cobalt versus iron are discussed.

Liu, Fuyi; Li, Ming; Tan, Lin; Armentrout, P. B.

2008-05-01

364

Frequency and activity of autorosette forming cells in Con-A activated PBL from women with hyperplasia or carcinoma of the endometrium--possible role of estrogens.  

PubMed

In a previous study we showed that endometrial carcinoma (EC) patients have a T cell deficiency manifested in a reduced ability to be stimulated in vitro by PHA and to produce IL-2. In an attempt to understand the mechanism responsible for this alteration we present in this paper a study on T cells characterized by the ability to form rosettes, with human erythrocytes, following Con-A activation (designated auto-rosette forming cells--ARFC). These cells are also known to manifest suppressive activity. We show that the frequency of ARFC in con-A activated peripheral blood leukocytes (PBMC) of EC patients is significantly (2-5 fold) higher than that of healthy age-matched controls or that of patients with stage--I colon or vaginal cancer. Endometrial carcinoma is known to be associated with long term exposure to estrogens unopposed by progestins. Examining the possible role of estrogens in increasing the frequency of ARFC from EC patients, we found that in vitro addition of estradiol to Con-A stimulated PBMC from healthy donors increased the frequency of ARFC to levels found in EC patients. Tamoxifen, an anti estrogen drug, reduced the frequency of the estrogen stimulated ARFC to the original low level. Our results suggest a dual role for estrogen in carcinogenesis as well as in immunomodulation. PMID:1967003

Yron, I; Kalechman, Y; Langer, A; Lidor, I; Luria, B; Luria, H; Ovadia, J; Pardo, Y; Shohat, L

1990-11-01

365

Role for cheR of Vibrio fischeri in the Vibriosquid Cindy R. DeLoney-Marino and Karen L. Visick  

E-print Network

, and rap- idly becomes colonized by the bioluminescent bacterium Vi- brio fischeri shortly after hatching into and permanent colonization by V. fischeri, while excluding all other species of bacteria found in the seawater direct the bacteria towards the organ's surface (Nyholm et al. 2000, 2002). The bacteria are thus swept

McFall-Ngai, Margaret

366

ANÁLISIS DE FRECUENTACIÓN DEL TURISMO NAÚTICO- RECREATIVO DEL MEDIO MARINO DE LA ISLA DE MENORCA. CONSECUENCIAS AMIENTALES DE SU FALTA DE REGULACIÓN 1  

Microsoft Academic Search

Menorca has experienced a growing popularity with regard to nautical tourism, as shown by saturated coles and beaches in the summer. The large number of boats found in some coastal spots can generate serious environmental problems on the Posidonia oceanica prairies, as well as on loading capacity and perception among the beach visitors.

FRANCESC XAVIER ROIG I MUNAR

2003-01-01

367

Atti 17a Conferenza Nazionale ASITA -Riva del Garda 5-7 novembre 2013 Caratterizzazione dell'ambiente marino dei Campi Flegrei.  

E-print Network

delle zone vulcaniche più pericolose e popolate del mondo e comprende la parte occidentale della città. Abstract The caldera of the Phlegraean Fields (also known as Campi Flegrei) is one of the most dangerous (positive or negative) of part of the Earth's surface (bradyseism) combined, only during the positive phase

New Hampshire, University of

368

Metales pesados en organismos marinos de la zona costera de la Patagonia argentina continental Heavy metals in marine organisms from the coastal zone of Continental Argentine Patagonia  

Microsoft Academic Search

Hg, Cd, Pb, Cu and Zn were analyzed in mollusks, crustaceans (soft tissue - µg\\/g dry weight), seabirds and marine mammals (kidney, liver and muscle - µg\\/g wet weight), from Patagonian coast of Argentina. Levels of Hg were undetected or very low. Higher than allowable Cd levels for human consumption were recorded in some mollusks (up to 6.75 µg\\/g), even

Mónica N. Gil; Américo Torres; Miguel Harvey; José Luis Esteves

2006-01-01

369

A Designed Protein Interface That Blocks Fibril Formation Ushma J. Shukla, Heather Marino, Po-Ssu Huang, Stephen L. Mayo, and John J. Love*,  

E-print Network

-A. Monomer-B fibrils were subjected to TEM imaging to confirm that the fibrils formed were indeed amyloid multimers. Unlike native complexes, some proteins as- semble erroneously, resulting in amyloid fibrils-reactive protein has been shown to break down amyloid deposits in the body.3 In addition, Dumoulin et al. recently

Love, John J.

370

Humanities 3 (John Marino) Film is Required Viewing; Optional Extra Credit Natalie Zemon Davis, The Return of Martin Guerre (Cambridge, Mass.: Harvard University  

E-print Network

to help readers understand the problem of self and community at the heart of the case of establishing house late, reads marriage contract, contract signed, marriage feast begins, and couple blessed" attack Martin and Bertrande on a walk, uncle dismisses accusations, Martin's request to square accounts

Russell, Lynn

371

A methodological approach to comparing pros and cons of delocalizing villages: socio-economic and technical issues  

NASA Astrophysics Data System (ADS)

On 7th March 2005, prolonged rainfalls combined with snowfalls activated a wide complex rock slide-earth flow that partly destroyed the village of Cavallerizzo at Cerzeto (Calabria, Southern Italy). Superposed tectonic units made of Palaeozoic metamorphic rocks, overlain by Miocene-Quaternary clastic terrains, crop out in the study area. The main scarp of the landslide developed by a recent normal fault, striking N-S along the western margin of the Crati graben and extended ca. 25 km. In its lower part, the phenomenon evolved in two main earth-flow bodies that extended along minor drainages and then merged along the S. Nicola torrent. The sector affected by the instability actually belongs to a large-scale slope movement: the 2005 activation was in fact only a paroxysmal episode of a long history of slope deformations, noticed in the area since the XVIII century. Warning signs had been recorded for weeks before the collapse, and the threatened area had been put under monitoring by CNR-IRPI. When the movement accelerated, people had already been alerted and evacuated (329 out of 581 inhabitants of Cerzeto were sheltered in nearby villages), thus neither victims nor injured were recorded. As a whole, 124 buildings were severely damaged or destroyed, the main road was interrupted. Immediately after the 7th March 2005 event, the national Department for Civil Protection decided to evaluate the feasibility of delocalizing Cavallerizzo to another site. At this purpose, CNR-IRPI was asked to analysing the "geological suitability" of 3 different sites (Pianette, Amatine, and Colombra), pre-selected by the same Municipality of Cerzeto in accordance to the Civil Protection; the results of the study were completed in early Summer 2005. Between October 2007 and December 2011, a new settlement was realized by the Italian Government, and the houses were delivered to people once living at Cavallerizzo. In the last years, the socio-economic effects of the delocalization of Cavallerizzo have been analysed within the frame of a PhD thesis by one of the authors. The present study focuses on the Cavallerizzo case study to discuss a methodological approach useful to comparing pros and cons of delocalizing villages, aiming at properly considering socio-economic effects in addition to technical issues.

Guadagno, Eleonora; Iovine, Giulio G. R.; Petrucci, Olga; Forciniti, Pinuccia R.

2014-05-01

372

Informe Anual a la Nación sobre el Estado del Cáncer, de 1975 a 2010, con una sección especial sobre la prevalencia de comorbilidad y su efecto en la supervivencia de personas con cáncer de pulmón, seno, próstata o colorrectal: preguntas y respuestas  

Cancer.gov

El Informe Anual a la Nación sobre el Estado del Cáncer (1975 a 2010), mostró un descenso más acelerado que en años anteriores de los índices de mortalidad por cáncer de pulmón. También contiene una sección especial que destaca los efectos significativos que tienen otras enfermedades en la supervivencia de pacientes con cáncer.

373

15-Deoxy-?12,14-prostaglandin J2 Reduces Liver Impairment in a Model of ConA-Induced Acute Hepatic Inflammation by Activation of PPAR? and Reduction in NF-?B Activity  

PubMed Central

Objective. 15-Deoxy-?12,14-prostaglandin J2 (15d-PGJ2) reduces inflammation and has been identified as an anti-inflammatory prostaglandin in numerous animal models. In this study, we investigated both effects of 15d-PGJ2 and its protection mechanism in concanavalin A- (ConA-) induced autoimmune hepatitis in mice. Materials and Methods. In vivo, Balb/C mice were injected with ConA (25?mg/kg) to induce acute autoimmune hepatitis, and 15d-PGJ2 (10??g or 25??g) was administered 1?h before the ConA injection. The histological grade, proinflammatory cytokine levels, and NF-?B and PPAR? activity were determined 6, 12, and 24?h after the ConA injection. In vitro, LO2 cells and RAW264.7 cells were pretreated with 15d-PGJ2 (2??M) 1?h before the stimulation with ConA (30??g/mL). The NF-?B and PPAR? activity were determined 30?min after the ConA administration. Results. Pretreatment with 15d-PGJ2 reduced the pathological effects of ConA-induced autoimmune hepatitis and significantly reduced the levels of cytokines after injection. 15d-PGJ2 activated PPAR?, blocked the degradation of I?B?, and inhibited the translocation of NF-?B into the nucleus. Conclusion. These results indicate that 15d-PGJ2 protects against ConA-induced autoimmune hepatitis by reducing proinflammatory cytokines. This reduction in inflammation may correlate with the activation of PPAR? and the reduction in NF-?B activity. PMID:25120564

Chen, Kan; Li, Jingjing; Wang, Junshan; Xia, Yujing; Dai, Weiqi; Wang, Fan; Shen, Miao; Cheng, Ping; Zhang, Yan; Wang, Chengfen; Yang, Jing; Zhu, Rong; Zhang, Huawei; Zheng, Yuanyuan; Lu, Jie; Fan, Zhuoyi; Zhou, Yingqun; Guo, Chuanyong

2014-01-01

374

Flight Deck Surface Trajectory-based Operations (STBO): Results of Piloted Simulations and Implications for Concepts of Operation (ConOps)  

NASA Technical Reports Server (NTRS)

The results offour piloted medium-fidelity simulations investigating flight deck surface trajectory-based operations (STBO) will be reviewed. In these flight deck STBO simulations, commercial transport pilots were given taxi clearances with time and/or speed components and required to taxi to the departing runway or an intermediate traffic intersection. Under a variety of concept of operations (ConOps) and flight deck information conditions, pilots' ability to taxi in compliance with the required time of arrival (RTA) at the designated airport location was measured. ConOps and flight deck information conditions explored included: Availability of taxi clearance speed and elapsed time information; Intermediate RTAs at intermediate time constraint points (e.g., intersection traffic flow points); STBO taxi clearances via ATC voice speed commands or datal ink; and, Availability of flight deck display algorithms to reduce STBO RTA error. Flight Deck Implications. Pilot RTA conformance for STBO clearances, in the form of ATC taxi clearances with associated speed requirements, was found to be relatively poor, unless the pilot is required to follow a precise speed and acceleration/deceleration profile. However, following such a precise speed profile results in inordinate head-down tracking of current ground speed, leading to potentially unsafe operations. Mitigating these results, and providing good taxi RTA performance without the associated safety issues, is a flight deck avionics or electronic flight bag (EFB) solution. Such a solution enables pilots to meet the taxi route RTA without moment-by-moment tracking of ground speed. An avionics or EFB "error-nulling" algorithm allows the pilot to view the STBO information when the pilot determines it is necessary and when workload alloys, thus enabling the pilot to spread his/her attention appropriately and strategically on aircraft separation airport navigation, and the many other flight deck tasks concurrently required. Surface Traffic Management (STM) System Implications. The data indicate a number of implications regarding specific parameters for ATC/STM algorithm development. Pilots have a tendency to arrive at RTA points early with slow required speeds, on time for moderate speeds, and late with faster required speeds. This implies that ATC/STM algorithms should operate with middle-range speeds, similar to that of non-STBO taxi performance. Route length has a related effect: Long taxi routes increase the earliness with slow speeds and the lateness with faster speeds. This is likely due to the" open-loop" nature of the task in which the speed error compounds over a longer time with longer routes. Results showed that this may be mitigated by imposing a small number oftime constraint points each with their own RTAs effectively tuming a long route into a series of shorter routes - and thus improving RTA performance. STBO ConOps Implications. Most important is the impact that these data have for NextGen STM system ConOps development. The results of these experiments imply that it is not reasonable to expect pilots to taxi under a "Full STBO" ConOps in which pilots are expected to be at a predictable (x,y) airport location for every time (t). An STBO ConOps with a small number of intermediate time constraint points and the departing runway, however, is feasible, but only with flight deck equipage enabling the use of a display similar to the "error-nulling algorithm/display" tested.

Foyle, David C.; Hooey, Becky L.; Bakowski, Deborah L.

2013-01-01

375

DYNAMIC FRICTION EXPERIMENTS AT THE ATLAS PULSED POWER C. L. Rousculp, J. E. Hammerberg, D. M. Oro, G. Rodriguez, P. M. Goodwin,  

E-print Network

DYNAMIC FRICTION EXPERIMENTS AT THE ATLAS PULSED POWER FACILITY C. L. Rousculp, J. E. Hammerberg, D contract DE-AC52-06NA25396 Abstract A Series of dynamic friction experiments has been conducted frictional forces occurring there. Other diagnostics included a single-point VISAR and line-ORVIS to measure

Kurien, Susan

376

Childhood apraxia of speech and multiple phonological disorders in Cairo-Egyptian Arabic speaking children: Language, speech, and oro-motor differences  

Microsoft Academic Search

Childhood apraxia of speech is a neurological childhood speech-sound disorder in which the precision and consistency of movements underlying speech are impaired in the absence of neuromuscular deficits. Children with childhood apraxia of speech and those with multiple phonological disorder share some common phonological errors that can be misleading in diagnosis. This study posed a question about a possible significant

Azza Adel Aziz; Sahar Shohdi; Dalia Mostafa Osman; Emad Iskander Habib

2010-01-01

377

On the role of localized surface plasmon resonance in UV-Vis light irradiated Au/TiO2 photocatalysis systems: pros and cons.  

PubMed

The role of localized surface plasmon resonance (LSPR) in UV-Vis light irradiated Au/TiO2 photocatalysis systems has been investigated, and it is demonstrated experimentally for the first time that both pros and cons of LSPR exist simultaneously for this photocatalytic reaction. We have proved that when operating under mixed UV and green light irradiation, the LSPR injected hot electrons (from the Au nanoparticles to TiO2 under green light irradiation) may surmount the Schottky barrier (SB) formed between the Au nanoparticles and TiO2, and flow back into the TiO2. As a result, these electrons may compensate for and even surpass those transferred from TiO2 to the Au nanoparticles, thus accelerating the recombination of UV excited electron-hole pairs in TiO2. This is the negative effect of LSPR. On the other hand, more hot electrons existing on the surface of the Au nanoparticles due to LSPR would favor the photocatalytic reaction, which accompanied by the negative effect dominates the overall photocatalytic performance. The presented results reveal the multi-faceted essence of LSPR in Au/TiO2 structures, and is instructive for the application of metal-semiconductor composites in photocatalysis. Moreover, it is confirmed that the extent to which the above pros and cons of LSPR dominate the overall photocatalytic reaction depends on the intensity ratio of visible to UV light. PMID:25665512

Lin, Zhongjin; Wang, Xiaohong; Liu, Jun; Tian, Zunyi; Dai, Loucheng; He, Beibei; Han, Chao; Wu, Yigui; Zeng, Zhigang; Hu, Zhiyu

2015-02-19

378

Aceptabilidad del diagnóstico rápido casero para HIV entre hombres gay y otros hombres que tienen sexo con hombres (G&HSH) de la Ciudad de Buenos Aires  

PubMed Central

Resumen El uso del diagnóstico rápido para HIV en Argentina, así como otros países de Latinoamérica, ha sido limitado hasta el momento. Este trabajo reporta los resultados provenientes de un estudio cualitativo realizado entre hombres gays y otros hombres que tienen sexo con hombres (G&HSH) de la Ciudad de Buenos Aires, Argentina. El objetivo principal del mismo fue conocer las ventajas y desventajas que los hombres G&HSH perciben en relación al diagnóstico rápido casero para HIV. Se realizaron ocho grupos focales con 73 participantes en los cuales se discutió acerca de las ventajas y desventajas del uso de los diagnósticos rápidos. Las respuestas fueron codificadas utilizando un programa para análisis de datos cualitativos (NVivo) y analizadas temáticamente. Los participantes describieron numerosas ventajas sobre el uso del diagnóstico rápido casero, aunque algunos reportaron importantes preocupaciones dentro de las cuales se destaca la posibilidad de impulsos suicidas si alguien recibe un resultado positivo estando solo. En términos generales se observó una gran aceptabilidad para el uso del diagnóstico rápido si el mismo es realizado por personal de salud en lugares acondicionados para este fin. PMID:25284951

Balán, Iván C.; Carballo-Diéguez, Alex; Marone, Rubén O.; Pando, María A.; Barreda, Victoria; Ávila, María M.

2011-01-01

379

FACTORES SOCIO-ESTRUCTURALES Y EL ESTIGMA HACIA EL VIH/SIDA: EXPERIENCIAS DE PUERTORRIQUEÑOS/AS CON VIH/SIDA AL ACCEDER SERVICIOS DE SALUD  

PubMed Central

RESUMEN El estigma relacionado al VIH/SIDA continúa afectando la prestación de servicios de salud y el bienestar físico y mental de las personas con VIH/SIDA (PVS). Recientemente la literatura científica ha señalado la importancia de comprender las manifestaciones de estigma más allá de las interacciones individuales. Por tal razón, investigaciones recientes en y fuera de Puerto Rico enfatizan la importancia de entender cómo factores socio-estructurales (FSE) influyen en los procesos de estigmatización social. Con el propósito de examinar los FSE que influyen en las manifestaciones de estigma relacionado al VIH/SIDA, realizamos y analizamos nueve grupos focales compuestos por hombres y mujeres en tratamiento para el VIH/SIDA que habían tenido experiencias estigmatizantes. Los participantes identificaron FSE relacionados a las manifestaciones de estigma, tales como el uso de viviendas especializadas, descentralización de los servicios de salud y el desarrollo de protocolos administrativos excluyentes en los servicios de salud. Los resultados demuestran la importancia de considerar los FSE en el desarrollo e implementación de intervenciones dirigidas a la población. PMID:24639599

RIVERA-DIAZ, MARINILDA; VARAS-DIAZ, NELSON; REYES-ESTRADA, MARCOS; SURO, BEATRIZ; CORIANO, DORALIS

2013-01-01

380

The International Consortium on Lithium Genetics (ConLiGen): an initiative by the NIMH and IGSLI to study the genetic basis of response to lithium treatment.  

PubMed

For more than half a decade, lithium has been successfully used to treat bipolar disorder. Worldwide, it is considered the first-line mood stabilizer. Apart from its proven antimanic and prophylactic effects, considerable evidence also suggests an antisuicidal effect in affective disorders. Lithium is also effectively used to augment antidepressant drugs in the treatment of refractory major depressive episodes and prevent relapses in recurrent unipolar depression. In contrast to many psychiatric drugs, lithium has outlasted various pharmacotherapeutic 'fashions', and remains an indispensable element in contemporary psychopharmacology. Nevertheless, data from pharmacogenetic studies of lithium are comparatively sparse, and these studies are generally characterized by small sample sizes and varying definitions of response. Here, we present an international effort to elucidate the genetic underpinnings of lithium response in bipolar disorder. Following an initiative by the International Group for the Study of Lithium-Treated Patients (www.IGSLI.org) and the Unit on the Genetic Basis of Mood and Anxiety Disorders at the National Institute of Mental Health,lithium researchers from around the world have formed the Consortium on Lithium Genetics (www.ConLiGen.org) to establish the largest sample to date for genome-wide studies of lithium response in bipolar disorder, currently comprising more than 1,200 patients characterized for response to lithium treatment. A stringent phenotype definition of response is one of the hallmarks of this collaboration. ConLiGen invites all lithium researchers to join its efforts. PMID:20453537

Schulze, Thomas G; Alda, Martin; Adli, Mazda; Akula, Nirmala; Ardau, Raffaella; Bui, Elise T; Chillotti, Caterina; Cichon, Sven; Czerski, Piotr; Del Zompo, Maria; Detera-Wadleigh, Sevilla D; Grof, Paul; Gruber, Oliver; Hashimoto, Ryota; Hauser, Joanna; Hoban, Rebecca; Iwata, Nakao; Kassem, Layla; Kato, Tadafumi; Kittel-Schneider, Sarah; Kliwicki, Sebastian; Kelsoe, John R; Kusumi, Ichiro; Laje, Gonzalo; Leckband, Susan G; Manchia, Mirko; Macqueen, Glenda; Masui, Takuya; Ozaki, Norio; Perlis, Roy H; Pfennig, Andrea; Piccardi, Paola; Richardson, Sara; Rouleau, Guy; Reif, Andreas; Rybakowski, Janusz K; Sasse, Johanna; Schumacher, Johannes; Severino, Giovanni; Smoller, Jordan W; Squassina, Alessio; Turecki, Gustavo; Young, L Trevor; Yoshikawa, Takeo; Bauer, Michael; McMahon, Francis J

2010-01-01

381

Potential pros and cons of external healthcare performance evaluation systems: real-life perspectives on Iranian hospital evaluation and accreditation program  

PubMed Central

Background: Performance evaluation is essential to quality improvement in healthcare. The current study has identified the potential pros and cons of external healthcare evaluation programs, utilizing them subsequently to look into the merits of a similar case in a developing country. Methods: A mixed method study employing both qualitative and quantitative data collection and analysis techniques was adopted to achieve the study end. Subject Matter Experts (SMEs) and professionals were approached for two-stage process of data collection. Results: Potential advantages included greater attractiveness of high accreditation rank healthcare organizations to their customers/purchasers and boosted morale of their personnel. Downsides, as such, comprised the programs’ over-reliance on value judgment of surveyors, routinization and incurring undue cost on the organizations. In addition, the improved, standardized care processes as well as the judgmental nature of program survey were associated, as pros and cons, to the program investigated by the professionals. Conclusion: Besides rendering a tentative assessment of Iranian hospital evaluation program, the study provides those running external performance evaluations with a lens to scrutinize the virtues of their own evaluation systems through identifying the potential advantages and drawbacks of such programs. Moreover, the approach followed could be utilized for performance assessment of similar evaluation programs. PMID:25279381

Jaafaripooyan, Ebrahim

2014-01-01

382

Estudio de la fotoabsorción y fotoionización de la molécula de alta relevancia atmosférica no a través de los estados Rydberg con la metodología MQDO  

NASA Astrophysics Data System (ADS)

Los procesos de fotoionización son de una importancia fundamental [1] y encuentran aplicación en un gran número de contextos científicos: Astrofísica [2], química de las radiaciones, biología. Los investigadores de dichos campos, necesitan de valores de fiables de secciones eficaces para la fotoionización parcial, la Fotoabsorción, así como para los procesos de fotofragmentación en amplios intervalos espectrales, particularmente en estudios de modelización [3-5]. En este trabajo se ha centrado la atención sobre el oxido nítrico, que se ha considerado apropiado y relevante por varios motivos: por el trascendental papel que representa en la física y química de la alta atmosfera [6], aparte de por estar íntimamente relacionado con los problemas de contaminación. Los procesos de recombinación disociativa [7] del NO, donde los estados Rydberg se encuentran directamente implicados, son relevantes, por ejemplo, en las regiones E y F de la ionosfera [7]. En este trabajo se estudia la fotoionización del NO desde el estado fundamental con la versión molecular del método del orbital de defecto cuántico (MQDO). Para ello se calcula el diferencial de las fuerzas de oscilador parciales que constituyen los canales de fotoionización del NO desde el estado fundamental. La continuidad del diferencial de fuerza de oscilador calculada a través del umbral de fotoionización, esto es, en las regiones del espectro discreta y del continua, se adopta como criterio de calidad la escasez de datos comparativos [8].

Bustos, E.; Velasco, A. M.; Martín, I.; Lavín, C.

383

A wireless, remote-query and high sensitivity Escherichia coli O157: H7 biosensor based on the recognition action of Con A  

PubMed Central

Escherichia coli O157: H7 is detected using a remote-query (wireless, passive) magnetoelastic sensor platform to which a 1 µm-thick layer of Bayhydrol 110 and then a layer of functionalized mannose is applied. The multivalent binding of lectin concanavalin A (Con A) to the E. coli surface O-antigen and mannose favors the strong adhesion of E. coli to the mannose modified magnetoelastic sensor; E. coli is rigidly and strongly attached on the mannose-modified sensor through Con A, which works as a bridge to bind to the E. coli surface O-antigen and mannose modified sensor surface. As E. coli is bound to the sensor its resonance frequency shifts, enabling quantification of E. coli concentration with a limit of detection of 60 cells/mL and a linear logarithmic response range of 6.0×101 to 6.1×109 cells/mL. The analysis can be directly conducted without incubation, and completed in 3 h or less. PMID:19548666

Lu, Qingzhu; Lin, Hailan; Ge, Shutian; Luo, Shenglian; Cai, Qingyun; Grimes, Craig A.

2009-01-01

384

A Novel In Vivo siRNA Delivery System Specifically Targeting Liver Cells for Protection of ConA-Induced Fulminant Hepatitis  

PubMed Central

Background Fulminant hepatitis progresses to acute liver failure (ALF) when the extent of hepatocyte death exceeds the liver's regenerative capacity. Although small interfering RNA (siRNA) appears promising in animal models of hepatitis, the approach is limited by drawbacks associated with systemic administration of siRNA. The aim of this study is to develop a hepatocyte-specific delivery system of siRNA for treatment of fulminant hepatitis. Methodology/Principal Findings Galactose-conjugated liposome nano-particles (Gal-LipoNP) bearing siRNA was prepared, and the particle size and zeta potential of Gal-LipoNP/siRNA complexes were measured. The distribution, cytotoxicity and gene silence efficiency were studied in vivo in a concanavalin A (ConA)-induced hepatitis model. C57BL/6 mice were treated with Gal-LipoNP Fas siRNA by i.v. injection 72 h before ConA challenge, and hepatocyte injury was evaluated using serum alanine transferase (ALT) and aspartate transaminase (AST) levels, as well as liver histopathology and TUNEL-positive hepatocytes. The galactose-ligated liposomes were capable of encapsulating >96% siRNA and exhibited a higher stability than naked siRNA in plasma. Hepatocyte-specific targeting was confirmed by in vivo delivery experiment, in which the majority of Gal-LipoNP-siRNA evaded nuclease digestion and accumulated in the liver as soon as 6 h after administration. In vivo gene silencing was significant in the liver after treatment of Gal-Lipo-siRNA. In the ConA-induced hepatitis model, serum levels of ALT and AST were significantly reduced in mice treated with Gal-lipoNP-siRNA as compared with control mice. Additionally, tissue histopathology and apoptosis showed an overall reduction of injury in the Gal-LipoNP siRNA-treated mice. Conclusions/Significance This study is the first to our knowledge to demonstrate reduction of hepatic injury by liver-specific induction of RNA interference using Gal-LipoNP Fas siRNA, highlighting a novel RNAi-based therapeutic potential in many liver diseases. PMID:22970170

Jiang, Nan; Zhang, Xusheng; Zheng, Xiufen; Chen, Di; Siu, Kingsun; Wang, Hongmei; Ichim, Thomas E.; Quan, Douglas; McAlister, Vivian; Chen, Guihua; Min, Wei-Ping

2012-01-01

385

The soil-water balance simulations of a grassland in response to CO2, rainfall, and biodiversity manipulations at BioCON  

NASA Astrophysics Data System (ADS)

The BioCON (Biodiversity, CO2 and N) experiment has been continuously running since 1997. Operated by the University of Minnesota and located within the Cedar Creek Ecosystem Science Reserve in Minnesota, USA, BioCON is a Free-Air CO2 Enrichment (FACE) experiment that investigates plant community response to three key environmental variables: nitrogen, atmospheric CO2 and biodiversity. More recently rainfall exclusion and temperature manipulation were added to the experiment which amounts to 371 plots. The site attempts to replicate predicted average temperature increases and a northern shift of plant species and any associated consequences. FACE experiments have been conducted for a number of years in different countries, but the focus has generally been on how plant communities, soil respiration and microbes respond. Minimal work has been focused on the hydrologic aspects of these experiments which are potentially valuable for investigating global warming effects on local and plot-scale ecohydrology. Thus, the objective of this work is to characterize and model unsaturated flow for different CO2 and rainfall treatments in order to see how they affect soil moisture dynamics and groundwater recharge on grasslands of central Minnesota. Our study focuses on simulating soil moisture dynamics in eighteen of the BioCON plots: six bare plots with regular rainfall regimes (zero plant species, three plots with elevated atmospheric CO2 levels), six regular rainfall regimes (nine plant species, three plots with elevated atmospheric CO2 levels) and six reduced rainfall regimes (nine plant species, three plots with elevated atmospheric CO2 levels). The Simultaneous Heat and Water (SHAW) model, which solves the Richards equation for unsaturated zone water flow coupled to a comprehensive energy balance model, was parameterized with a combination of field and lab estimates of soil properties. Field estimates of saturated hydraulic conductivity using tension infiltrometers ranged from 9.8 x 10-4 to 6.7 x 10-3 cm/s. Soil cores were collected and analyzed for soil hydraulic properties (texture, unsaturated hydraulic conductivity and moisture retention). From the grain size analyzes of soil samples collected every 10 cm until 1m depth, the soil is homogenous and on average 87% sand, 11% silt and 2% clay. We will be presenting results from the simulations and statistical comparisons to observations of soil moisture at four depths in each plot.

Flinker, R. H.; Cardenas, M.; Caldwell, T. G.; Rich, R.; Reich, P.

2013-12-01

386

Intracellular free zinc up-regulates IFN-? and T-bet essential for Th1 differentiation in Con-A stimulated HUT-78 cells  

PubMed Central

Zinc deficiency impairs cellular immunity. Up-regulation of mRNA levels of IFN-?, IL-12R?2, and T-bet are essential for Th1 differentiation. We hypothesized that zinc increases Th1 differentiation via up-regulation of IFN-? and T-bet expression. To test this hypothesis, we used zinc-deficient and zinc-sufficient HUT-78 cells (a Th0 cell line) under different condition of stimulation in this study. We also used TPEN, a zinc-specific chelator, to decrease the bioavailability of zinc in the cells. We measured intracellular free zinc, cytokines, and the mRNAs of T-bet, IFN-?, and IL-12R?2. In this study, we show that in zinc-sufficient HUT-78 cells (a Th0 cell line), mRNA levels of IFN-?, IL-12R?2, and T-bet in PMA/PHA-stimulated cells were increased in comparison to zinc-deficient cells. Although intracellular free zinc was increased slightly in PMA/PHA-stimulated cells, Con-A-stimulated cells in 5 ?M zinc medium showed a greater sustained increase in intracellular free zinc in comparison to cells incubated in 1 ?M zinc. The cells pre-incubated with TPEN showed decreased mRNA levels of IFN-? and T-bet mRNAs in comparison to cells without TPEN incubation. We conclude that stimulation of cells by Con-A via TCR, release intracellular free zinc which functions as a signal molecule for generation of IFN-? and T-bet, and IL-12Rb?2 mRNAs required for Th1 cell differentiation. These results suggest that zinc increase Th1 cell differentiation by up-regulation of IFN-? and T-bet, and IL-12Rb?2 mRNAs. PMID:21439265

Bao, Bin; Prasad, Ananda S.; Beck, Frances WJ; Bao, Ginny W.; Singh, Tapinder; Ali, Shadan; Sarkar, Fazlul H.

2011-01-01

387

ChIP Protocol for EZ-Magna ChIPTM A--anti-GFP, P19 cells *70% con)luent 6cm dish contains ~6.5 million P19 cells.  

E-print Network

. Resuspend the cell pellet with 500ul ice-cold PBS w/ 1X Protease inhibitor cocktail. Resuspend the pellet in 500ul of cell lysis buffer w/ 1X protease inhibitorChIP Protocol for EZ-Magna ChIPTM A--anti-GFP, P19 cells *70% con)luent 6cm

Oliver, Douglas L.

388

Collisions of matter-wave solitonsSupplementary Information for Collisions of matter-wave solitons Supplementary Figure 1: Comparison between the expansion of a soliton and a repulsive con-  

E-print Network

Collisions of matter-wave solitonsSupplementary Information for Collisions of matter-wave solitons Supplementary Figure 1: Comparison between the expansion of a soliton and a repulsive con- densate. a, the soliton propagates without dispersion, as expected. The small displacement in time is due to a slight time

Loss, Daniel

389

Liberación\\/mineralización de nitrógeno en hojarasca de Eucalyptus grandis y leguminosas herbáceas, su relación con la calidad física y química del residuo y su efecto sobre el crecimiento de plantas jóvenes de eucalipto  

Microsoft Academic Search

Resumen El tipo de cosecha y manejo de residuos inciden en el contenido de nutrientes del suelo y la productividad forestal. Estos residuos contienen la mayoría del retorno de N. La velocidad de provisión de nutrientes por la descomposición\\/mineralización puede verse afectada por la calidad química y física como por la localización y contacto de los residuos con el suelo.

Alcaraz Maria Luciana

390

PROYECTO SOSTAUGA: EL USO SOSTENIBLE DEL AGUA Y SU RELACIN CON EL TERRITORIO EN EL CAMPUS DE ELVIA Y DE LA ZAPATEIRA DE LA UNIVERSIDAD DE A CORUA_UDC  

E-print Network

aprovechamiento de las aguas residuales urbanas tanto en tiempo seco como de lluvia,1 PROYECTO SOSTAUGA: EL USO SOSTENIBLE DEL AGUA Y SU RELACIÃ?N CON EL TERRITORIO EN EL CAMPUS DE elemento agua y sus ecosistemas asociados. Preservar y potenciar un elemento clave del patrimonio socio

Fraguela, Basilio B.

391

IEEE TransacTIons on UlTrasonIcs, FErroElEcTrIcs, and FrEqUEncy conTrol, vol. 59, no. 1, JanUary 2012156 08853010/$25.00 2012 IEEE  

E-print Network

IEEE TransacTIons on UlTrasonIcs, FErroElEcTrIcs, and FrEqUEncy conTrol, vol. 59, no. 1, JanUary 2012156 0885­3010/$25.00 © 2012 IEEE Abstract--Piezoelectric devices, such as piezoelectric trav- eling-wave rotary ultrasonic motors, have composite piezoelec- tric structures. A composite piezoelectric structure

Pugh, Mary

392

ANALISI MATEMATICA con ELEMENTI di ALGEBRA XX ottobre 2013 1. A = {a, b, . . ., v, z} `e l'insieme delle 21 lettere dell'alfabeto italiano. Quante sono le parole di  

E-print Network

'insieme delle 21 lettere dell'alfabeto italiano. Quante sono le parole di 6 lettere, formate con lettere di A. A = {a, b, . . ., v, z} `e l'insieme delle 21 lettere dell'alfabeto italiano. Quante sono le parole di 6

Serapioni, Raul

393

IEEE TransacTIons on UlTrasonIcs, FErroElEcTrIcs, and FrEqUEncy conTrol, vol. 60, no. 7, JUly 20131386 08853010/$25.00 2013 IEEE  

E-print Network

IEEE TransacTIons on UlTrasonIcs, FErroElEcTrIcs, and FrEqUEncy conTrol, vol. 60, no. 7, JUly heterogeneous tumors. RF echo data spanning the 1 to 12 MHz frequency range were acquired in three dimensions. These functional signal-to-noise ratios indicated that BSC versus frequency variations between systems ranged from

Illinois at Urbana-Champaign, University of

394

08853010/$25.00 TBC IEEE 1IEEE TransaCTIons on UlTrasonICs, FErroElECTrICs, and FrEqUEnCy ConTrol, vol. TBC, no. TBC, TBC TBC  

E-print Network

0885­3010/$25.00 © TBC IEEE 1IEEE TransaCTIons on UlTrasonICs, FErroElECTrICs, and FrEqUEnCy Con, density, and spatial organization ranging from tightly clustered to nearly regular to mimic a broad range distribution models used in ultrason- ics literature. section IV describes the pool of synthetic Us data

Clark, James J.

395

IEEE TransacTIons on UlTrasonIcs, FErroElEcTrIcs, and FrEqUEncy conTrol, vol. 59, no. 9, sEpTEmbEr 20122066 08853010/$25.00 2012 IEEE  

E-print Network

IEEE TransacTIons on UlTrasonIcs, FErroElEcTrIcs, and FrEqUEncy conTrol, vol. 59, no. 9, s, and michael oelze, Senior Member, IEEE Abstract--Quantitative ultrasonic techniques using back- scatter on the inverse cubic of the size. Diameters of the distributions ranged between [25, 100], [25, 50], [50, 100

Illinois at Urbana-Champaign, University of

396

IEEE TransacTIons on UlTrasonIcs, FErroElEcTrIcs, and FrEqUEncy conTrol, vol. 59, no. 12, dEcEmbEr 2012 2655 08853010/$25.00 2012 IEEE  

E-print Network

IEEE TransacTIons on UlTrasonIcs, FErroElEcTrIcs, and FrEqUEncy conTrol, vol. 59, no. 12, dEcEmbEr 2012 2655 0885­3010/$25.00 © 2012 IEEE Transthoracic Cardiac Ultrasonic Stimulation Induces a Negative- diac bioeffects resulting from ultrasonic stimulation using a specific set of acoustical parameters

Illinois at Urbana-Champaign, University of

397

Diffusional homogenization of light REE in garnet from the Day Nui Con Voi Massif in N-Vietnam: Implications for SmNd geochronology and timing of metamorphism in  

E-print Network

Diffusional homogenization of light REE in garnet from the Day Nui Con Voi Massif in N Keywords: Sm­Nd Lu­Hf Garnet dating Trace elements Diffusion Vietnam High-grade migmatitic and mylonitic diffusional profiles in garnet. Laser ablation ICP-MS analyses of trace elements indicate that REE and Hf

Demouchy, Sylvie

398

08853010/$25.00 2009 IEEE 2145IEEE TransacTIons on UlTrasonIcs, FErroElEcTrIcs, and FrEqUEncy conTrol, vol. 56, no. 10, ocTobEr 2009  

E-print Network

EqUEncy conTrol, vol. 56, no. 10, ocTobEr 2009 Abstract--State-of-the-art 3-D medical ultrasound imaging requires transmitting and receiving ultrasound using a 2-D array of ultrasound transducers with hundreds and transducer array can lead to a portable, high-performance, and inexpensive 3-D ultrasound imaging system

Khuri-Yakub, Butrus T. "Pierre"

399

Wound Healing & Management Node: Titles list Version 1 1 July 2010 Publication list of Evidence Summary titles available in the Wound Healing and Management Node of the JBI COnNECT+ database as at 31 December 2011.  

E-print Network

Wound Healing & Management Node: Titles list Version 1 1 July 2010 Publication list of Evidence Summary titles available in the Wound Healing and Management Node of the JBI COnNECT+ database as at 31 December 2011. Authors: The Wound Healing and Management Node Group This list is updated quarterly Evidence

400

VENDERE IL LEGNO CON RESPONSABILITA'  

E-print Network

mass media, le istituzioni pubbliche e private, ...) Definizione di green marketing = un'evoluzione del: "pettenella" www.tesaf.unipd.it/pettenella/index.html 1. Introduzione Dal Total marketing al Social marketing iniziative del settore pubblico #12;2 Evoluzione del marketing Fino agli anni '30 il m. si concentra sui

Pettenella, Davide

401

CONVIVIENDO CON EL MEDIO AMBIENTE  

Microsoft Academic Search

El desarrollo a nivel industrial, agrícola y urbano genera acciones contaminantes cuyo efecto puede ser inmediato o a largo plazo (la lluvia ácida, los gases que provocan el efecto invernadero y que contribuyen al cambio climático, la explotación excesiva de los recursos naturales, o la deforestación de la selva tropical). Esto provoca la extinción de diferentes especies de plantas o

Cristina Ferrer Lacosta

2009-01-01

402

Quantum computing: pro and con  

Microsoft Academic Search

I assess the potential of quantum computation. Broad and important applications must be found to justify construction of a quantum computer; I review some of the known quantum algorithms and consider the prospects for nding new ones. Quantum computers are notoriously susceptible to making errors; I discuss recently developed fault-tolerant procedures that enable a quantum computer with noisy gates to

Charles C. Lauritsen

403

Quantum computing: pro and con  

Microsoft Academic Search

I assess the potential of quantum computation. Broad and important applications must be found to justify construction of a quantum computer; I review some of the known quantum algorithms and consider the prospects for finding new ones. Quantum computers are notoriously susceptible to making errors; I discuss recently developed fault-tolerant procedures that enable a quantum computer with noisy gates to

John Preskill

1998-01-01

404

De conformidad con la Ley de Derechos Humanos de 1977 del Distrito de Columbia, segn enmendada, Cdigo Oficial del Distrito de Columbia, Seccin 2-1401.01 et seq., (Ley), el Distrito de Columbia no discrimina, de forma visible ni percibida, por  

E-print Network

De conformidad con la Ley de Derechos Humanos de 1977 del Distrito de Columbia, según enmendada la ausencia, el empleado no perderá ninguno de sus beneficios de empleo, ni tampoco los derechos por las estipuladas por la Ley. LAS QUEJAS CON RESPECTO A ALGUNA DENEGACI�N DE LOS DERECHOS EN VIRTUD DE

Weaver, Harold A. "Hal"

405

Coagulase-negative staphylococci (CoNS) isolated from ready-to-eat food of animal origin--phenotypic and genotypic antibiotic resistance.  

PubMed

The aim of this work was to study the pheno- and genotypical antimicrobial resistance profile of coagulase negative staphylococci (CoNS) isolated from 146 ready-to-eat food of animal origin (cheeses, cured meats, sausages, smoked fishes). 58 strains were isolated, they were classified as Staphylococcus xylosus (n = 29), Staphylococcus epidermidis (n = 16); Staphylococcus lentus (n = 7); Staphylococcus saprophyticus (n = 4); Staphylococcus hyicus (n = 1) and Staphylococcus simulans (n = 1) by phenotypic and genotypic methods. Isolates were tested for resistance to erythromycin, clindamycin, gentamicin, cefoxitin, norfloxacin, ciprofloxacin, tetracycline, tigecycline, rifampicin, nitrofurantoin, linezolid, trimetoprim, sulphamethoxazole/trimethoprim, chloramphenicol, quinupristin/dalfopristin by the disk diffusion method. PCR was used for the detection of antibiotic resistance genes encoding: methicillin resistance--mecA; macrolide resistance--erm(A), erm(B), erm(C), mrs(A/B); efflux proteins tet(K) and tet(L) and ribosomal protection proteins tet(M). For all the tet(M)-positive isolates the presence of conjugative transposons of the Tn916-Tn1545 family was determined. Most of the isolates were resistant to cefoxitin (41.3%) followed by clindamycin (36.2%), tigecycline (24.1%), rifampicin (17.2%) and erythromycin (13.8%). 32.2% staphylococcal isolates were multidrug resistant (MDR). All methicillin resistant staphylococci harboured mecA gene. Isolates, phenotypic resistant to tetracycline, harboured at least one tetracycline resistance determinant on which tet(M) was most frequent. All of the isolates positive for tet(M) genes were positive for the Tn916-Tn1545 -like integrase family gene. In the erythromycin-resistant isolates, the macrolide resistance genes erm(C) or msr(A/B) were present. Although coagulase-negative staphylococci are not classical food poisoning bacteria, its presence in food could be of public health significance due to the possible spread of antibiotic resistance. PMID:25475289

Chaj?cka-Wierzchowska, Wioleta; Zadernowska, Anna; Nalepa, Beata; Sierpi?ska, Magda; ?aniewska-Trokenheim, ?ucja

2015-04-01

406

IEEE TransacTIons on UlTrasonIcs, FErroElEcTrIcs, and FrEqUEncy conTrol, vol. 60, no. 3, March 2013524 08853010/$25.00 2013 IEEE  

E-print Network

IEEE TransacTIons on UlTrasonIcs, FErroElEcTrIcs, and FrEqUEncy conTrol, vol. 60, no. 3, March ranges of 4 to 6 µm and 6 to 8 µm). The stiffness was found to lie between 4 and 22 mN/m and to decrease exponentially with the microbubble size within the diameter range investigated. No cantilever spring constant

Konofagou, Elisa E.

407

IEEE TransacTIons on UlTrasonIcs, FErroElEcTrIcs, and FrEqUEncy conTrol, vol. 60, no. 11, novEmbEr 2013 2257 08853010/$25.00 2013 IEEE  

E-print Network

IEEE TransacTIons on UlTrasonIcs, FErroElEcTrIcs, and FrEqUEncy conTrol, vol. 60, no. 11, nov) pulse length (PL), ranging here from 67 s to 6.7 ms, on the physi- ology of the FUS-induced BBB opening at different acoustic pressures, ranging from 0.30 to 0.60 MPa. Permeability and volume of opening were both

Konofagou, Elisa E.

408

Study on the Strategies for the Soil and Water Resource Con-servation of Slopeland in Taiwan in Response to the Extreme Climate  

NASA Astrophysics Data System (ADS)

Global climate change results in extreme weather, especially ex-treme precipitation in Taiwan. Though the total amount of precipi-tation remains unchanged, the frequency of rainfall return period increases which affects slopeland and causes sediment disaster. In Taiwan, slopeland occupies about 73% of national territory. Under harsh environmental stress, soil and water conservation of slope-land becomes more important. In response to the trends of global-ization impacts of climate change, long term strategic planning be-comes more necessary. This study reviewed international practices and decision making process about soil and water conservation of slopeland; and conducted the compilation and analysis of water and soil conservation related research projects in Taiwan within the past five years. It is necessary for Taiwan to design timely adaptive strategies about conducting the all-inclusive conservation of na-tional territory, management and business operation of watershed based on the existing regulation with the effects of extreme weather induced by climate change and the changes of social-economic en-vironments. In order to realize the policy vision of "Under the premise of multiple uses, operating the sustainable business and management of the water and soil resources in the watershed through territorial planning in response to the climate and so-cial-economic environment change". This study concluded the future tasks for soil and water con-servation: 1.Design and timely amend strategies for soil and wand water conservation in response to extreme weather. 2. Strengthen the planning and operating of the land management and integrated conservation of the water and soil resources of key watershed. 3. Manage and operate the prevention of debris flow disaster and large-scale landslide. 4. Formulate polices, related regulations and assessment indicators of soil and water conservation. 5. Maintain the biodiversity of the slopeland and reduce the ecological footprint. 6. Conduct soil and water conservation research according to the importance and urgency of policies. 7. Implement the international cooperation, technology communication, talent cultivation, and integrated education and promotion.

Huang, Wen-Cheng

2014-05-01

409

100:2564-2576, 2008. First published Aug 27, 2008; doi:10.1152/jn.90688.2008J Neurophysiol Robert A. Marino, C. Kip Rodgers, Ron Levy and Douglas P. Munoz  

E-print Network

motor command signals. We collected extracellular single-unit recordings from 150 visual-motor (VM for Neuroscience Studies, 2 Canadian Institute of Health Research Group in Sensory-Motor Systems, 3 Departments.1152/jn.90688.2008. The oculomotor system is well understood compared with other motor systems; however

Munoz, Douglas Perry

410

Comunidades y arrecifes coralinos del Parque Nacional Marino Ballena, costa del Pacífico de Costa Rica Coral communities and reefs of Ballena Marine National Park, Pacific coast of Costa Rica  

Microsoft Academic Search

The coral communities and reefs at Ballena Marine National Park, on the southern Pacific coast of Costa Rica, were studied using three 10-m long transects per site, parallel to the coast, with 1-m2 quadrants. A total of 15 species of corals (11 hermatypic and 4 ahermatypic) were found, which when added to previous reports for the park makes a total

Juan José Alvarado; Jorge Cortés; Cindy Fernández; Jaime Nivia

411

Caracterización bioquímica del pasto marino Zostera marina en el límite sur de su distribución en el Pacífico Norte Biochemical characterization of the eelgrass Zostera marina at its southern distribution limit in the North Pacific  

Microsoft Academic Search

The eelgrass Zostera marina L. is distributed along the Baja California Peninsula (Mexico) where it is exposed to a wide range of irradiances and temperatures that could promote changes in its biochemical composition. Consequently, the objective of this study was to characterize the variations in the levels of chlorophyll, carbohydrates, proteins, fiber, ash and calories in the shoots of Z.

Alejandro Cabello-Pasini; Raquel Muñiz-Salazar; David H. Ward

412

Seventy-One Important Questions for the Conservation of Marine Biodiversity  

PubMed Central

The ocean provides food, economic activity, and cultural value for a large proportion of humanity. Our knowledge of marine ecosystems lags behind that of terrestrial ecosystems, limiting effective protection of marine resources. We describe the outcome of 2 workshops in 2011 and 2012 to establish a list of important questions, which, if answered, would substantially improve our ability to conserve and manage the world’s marine resources. Participants included individuals from academia, government, and nongovernment organizations with broad experience across disciplines, marine ecosystems, and countries that vary in levels of development. Contributors from the fields of science, conservation, industry, and government submitted questions to our workshops, which we distilled into a list of priority research questions. Through this process, we identified 71 key questions. We grouped these into 8 subject categories, each pertaining to a broad component of marine conservation: fisheries, climate change, other anthropogenic threats, ecosystems, marine citizenship, policy, societal and cultural considerations, and scientific enterprise. Our questions address many issues that are specific to marine conservation, and will serve as a road map to funders and researchers to develop programs that can greatly benefit marine conservation. Setenta y Un Preguntas Importantes para la Conservación de la Biodiversidad Marina Resumen Los océanos proporcionan alimento, actividad económica y valor cultural para una gran porción de la humanidad. Nuestro conocimiento de los ecosistemas marinos está atrasado con respecto al que tenemos de los ecosistemas terrestres, lo que limita la protección efectiva de los recursos naturales. Describimos el resultado de dos talleres en 2011 y 2012 para establecer una lista de preguntas importantes, las cuales al ser respondidas, mejorarían sustancialmente nuestra habilidad de conservar y manejar los recursos marinos del mundo. Entre los participantes se incluyeron a individuos de la docencia, el gobierno y organizaciones no-gubernamentales, con una amplia experiencia que atraviesa disciplinas, ecosistemas marinos y países que varían en el nivel de desarrollo. Los contribuyentes de los campos de la ciencia, la conservación, la industria y el gobierno, presentaron preguntas a nuestros talleres, las cuales separamos en una lista de preguntas de investigación prioritarias. Por medio de este proceso, identificamos 71 preguntas clave. Las agrupamos en ocho categorías temáticas, cada una perteneciente a un componente amplio de la conservación marina: pesquerías, cambio climático, otras amenazas antropogénicas, ecosistemas, ciudadanía marina, política, consideraciones sociales y culturales, y la iniciativa científica. Nuestras preguntas se dirigen a muchas cuestiones que son específicas de la conservación marina, y servirán como una ruta a seguir para patrocinadores e investigadores que busquen desarrollar programas que puedan beneficiar ampliamente a la conservación marina. PMID:24779474

PARSONS, E C M; FAVARO, BRETT; AGUIRRE, A ALONSO; BAUER, AMY L; BLIGHT, LOUISE K; CIGLIANO, JOHN A; COLEMAN, MELINDA A; CÔTÉ, ISABELLE M; DRAHEIM, MEGAN; FLETCHER, STEPHEN; FOLEY, MELISSA M; JEFFERSON, REBECCA; JONES, MIRANDA C; KELAHER, BRENDAN P; LUNDQUIST, CAROLYN J; MCCARTHY, JULIE-BETH; NELSON, ANNE; PATTERSON, KATHERYN; WALSH, LESLIE; WRIGHT, ANDREW J; SUTHERLAND, WILLIAM J

2014-01-01

413

Distribution of immune cells in head and neck cancer: CD8+ T-cells and CD20+ B-cells in metastatic lymph nodes are associated with favourable outcome in patients with oro- and hypopharyngeal carcinoma  

Microsoft Academic Search

BACKGROUND: Tumour infiltrating lymphocytes (TIL) are generally considered to represent a host immune response directed against tumour antigens. TIL are also increasingly recognised as possible prognostic parameters. However, the effects observed are variable indicating that results cannot be extrapolated from type of tumour to another. Moreover, it has been suggested that primary solid tumours may be ignored by the immune

Dominik Pretscher; Luitpold V Distel; Gerhard G Grabenbauer; Michael Wittlinger; Maike Buettner; Gerald Niedobitek

2009-01-01

414

Revision curricular a partir de un analisis comparativo de las discrepancias en los curriculos de una escuela de optometria en Puerto Rico con las competencias requeridas para las agencias de revalida y acreditacion 2004  

NASA Astrophysics Data System (ADS)

El proposito de esta investigacion, un estudio cualitativo de caso, fue comparar y contrastar el curriculo vigente de la Escuela de Optometria de la UIAPR con las competencias y estandares requeridos por las agencias de acreditacion y de revalida. Con este proposito, decidimos realizar una revision y un analisis de documentos: el prontuario de cada uno de los cursos de los curriculos implantados en el 1993 y en el 2001; las competencias y estandares establecidos por las agencias de revalida y de acreditacion; y las estadisticas en las que se analiza el porcentaje de estudiantes que aprueban cada una de las partes de los examenes de revalida entre el 1998 al 2003. Se realizaron entrevistas dirigidas para dar apoyo y complementar la revision y el analisis de estos documentos. Los participantes de las entrevistas fueron tres estudiantes de la clase de optometria del 2004 (ultima clase del curriculo del 1993); tres estudiantes de la clase de optometria del 2005 (primera clase graduanda del curriculo vigente) y tres profesores y/o directores de los Departamentos de Ciencias Basicas, Ciencias Clinicas y Cuidado al Paciente. Esta investigacion se enmarco en el modelo de evaluacion curricular de discrepancia de Malcolm Provus y en el modelo de desarrollo basado en competencias. Uno de los hallazgos mas importantes del estudio es que los cambios que se implantaron al curriculo del 2001 no han logrado que los estudiantes mejoren su ejecucion en los examenes de revalida. Por otro lado, se encontro que el curriculo vigente atiende completamente los estandares de la practica de Optometria, pero no las competencias. Esta informacion fue validada mediante el uso de una tabla de cotejo para el analisis de los cursos y de la informacion obtenida de las entrevistas. El estudio determina y concluye que existen discrepancias entre los prontuarios de los cursos del curriculo y las competencias requeridas por la agencia de revalida. Segundo, que el Departamento de Ciencias Basicas es el que presenta mas deficiencias en el desarrollo de las competencias. El investigador recomienda disenar e implantar un curriculo basado en competencias y proveer formacion en didactica y procesos de aprendizaje a los profesores.

Rivera Pacheco, Andres

415

26 CFR 1.955-4 - Definition of less developed country.  

Code of Federal Regulations, 2010 CFR

...Republic) Hong Kong Italy Japan Liechtenstein Luxembourg Monaco Netherlands New Zealand Norway Union of South Africa San Marino Sweden Switzerland United Kingdom. (c) Termination of designation. Section...

2010-04-01

416

26 CFR 1.955-4 - Definition of less developed country.  

Code of Federal Regulations, 2013 CFR

...Republic) Hong Kong Italy Japan Liechtenstein Luxembourg Monaco Netherlands New Zealand Norway Union of South Africa San Marino Sweden Switzerland United Kingdom. (c) Termination of designation. Section...

2013-04-01

417

26 CFR 1.955-4 - Definition of less developed country.  

...Republic) Hong Kong Italy Japan Liechtenstein Luxembourg Monaco Netherlands New Zealand Norway Union of South Africa San Marino Sweden Switzerland United Kingdom. (c) Termination of designation. Section...

2014-04-01

418

Millimeter-wave study of the CO-N 2 van der Waals complex: new measurements of CO- orthoN 2 and assignments of new states of CO- paraN 2  

NASA Astrophysics Data System (ADS)

Rotational transitions of the CO-N 2 van der Waals complex have been measured using the intracavity OROTRON jet spectrometer in the frequency range of 83-133 GHz. For the CO- orthoN 2 spin modification, the observed and assigned 21 rotational transitions belong to the Q- and P-branches of the K=1-0 subband. They complete the previous observation of the corresponding R-branch transitions. In the case of the less abundant form, CO- paraN 2, a new K=1 state, representing simultaneous rotation of both monomers, was detected for the first time. A total of 31 rotational transitions of CO- paraN 2 were assigned to two subbands connecting this new K=1 state with already known lower K=0 and 1 states. The assignments relied in part on energy level differences obtained from precise microwave data. The origin of the newly observed state was determined to be 3.41 cm -1 relative to the K=0 ground state of CO- paraN 2. The analysis yielded rotational parameters, centrifugal distortion parameters and nuclear quadrupole coupling constants due to the presence of two equivalent 14N nuclei for both CO- orthoN 2 and CO- paraN 2.

Surin, L. A.; Potapov, A. V.; Müller, H. S. P.; Panfilov, V. A.; Dumesh, B. S.; Giesen, T. F.; Schlemmer, S.

2006-08-01

419

Histochemical and immunohistochemical characterization of exocrine cells in the foregut of the red-eared slider turtle, Trachemys scripta (Emydidae).  

PubMed

The morphofunctional organization of the exocrine cells in the foregut of the red-eared slider turtle, Trachemys scripta, was investigated by histochemistry (PAS, AB pH1.0 and pH 2.5, HID-AB, Bowie), lectin-histochemistry (WGA, SBA, UEA, ConA, PNA, DBA, sialidase-SBA, sialidase-PNA, Paradoxical ConA), and immunohistochemistry (antipepsin, anti-alpha-H+,K+ ATPase) to detect regional differences and verify the existence of an oro-aboral gradient in gastric juice secretion. Observations showed that pharyngeal goblet cells have mucins with terminal residuals of GalNAc and sialic acid. In the oesophagus, sulphomucins in the goblet cells are progressively substituted by sialomucins and no glands are found. Gastric surface cells secrete mostly sialomucins with residuals of GlcNAc and GalNAc. The cardias presents glands with cells secreting mostly sialomucins, differing from the surface ones in having GalNAcalpha1,3GalNAc sequences. The fundus presents complex glands with main and lesser tubules. Cells in the main tubules secrete stable, class-III mucins with sialylated residuals of glucose and/or mannose, GalNAcalpha1, 3GalNAc, and Galbeta1,3GalNAc sequences. In the lesser tubules, the oxynticopeptic cells are found, presenting pepsinogen granules and an affinity to the anti-alpha-H+,K+ ATPase, without any oro-aboral variation. The pyloric glands have a secretion similar to that of the neck cells of the fundic glands, consisting of stable, class-III mucins mostly sialylated with a high heterogeneity of residuals such as glucose and/or mannose, fucose, GlcNAc, and GalNAc. Mucins in the foregut are probably involved in several functions such as lubrication, protection against gastric juice, osmotic regulation to increase intestinal absorption, and protection against microbial injuries. PMID:19556690

Scillitani, Giovanni; Liquori, Giuseppa Esterina; Mastrodonato, Maria; Ferri, Domenico

2008-12-01

420

The Big Con: China's Historical Sabotage  

ERIC Educational Resources Information Center

On June 4, 1989, the Chinese military, under orders from the highest levels of government, violently crushed peaceful civilian demonstrations in Beijing, most symbolically in and around Tiananmen Square. In the end, the Chinese government claimed that the death toll was approximately 200, but the Chinese Red Cross reported 2,000 to 3,000 deaths.…

Terrence Cheng

2009-01-01

421

Leiomioma uterino con extensión cardíaca: manejo anestésico  

Microsoft Academic Search

Summary A 61-year-old woman complaining of dyspnea with moderate effort was diagnosed with intravenous leiomyo- matosis arising in the inferior vena cava with right auri- cular extension. Surgery was performed in a one-stage procedure under extracorporeal circulation using atrio- tomy and venotomy of the inferior vena cava. Complete removal of the tumor was confirmed by transeso-phageal echocardiography during surgery. A

M. Jerez Anera; L. Delange Segura; J. Carmona Aurioles

422

Mjese las manos con agua tibia co-  

E-print Network

después de preparar alimentos Después de usar el baño o ayudar a un niño a usar el baño Después de manejar cada alimento y al cambiar de alimentos crudos a cocidos. Después de lavar, desinfecte los fre

423

Golden Rice - Evaluating the Pros and Cons  

NSDL National Science Digital Library

This activity engages students in evaluating the evidence and arguments related to Golden Rice and other possible strategies for preventing vitamin A deficiency. Students use this information to develop evidence-based conclusions about Golden Rice and the prevention of vitamin A deficiency. Students also develop questions that could provide important additional information for evaluating the arguments in favor of and opposed to Golden Rice and related policy proposals. In addition, students analyze how two reasonably accurate articles can present totally opposing points of view on this complex policy issue.

Waldron, Ingrid

424

Synthetic chemicals have been components of con-  

E-print Network

experi- mental animals are used1 and that products worth 5.6 trillion are regulated by such testing with the current approach to toxicology testing? An ideal study to under- stand whether an agent is harmful. The crucial question therefore is how useful are the cur- rent models, which are mostly animal models, and how

Cai, Long

425

Bilingual Education in Kyrgyzstan: Pros and Cons.  

ERIC Educational Resources Information Center

This paper discusses the potential of bilingual education and its possible implementation in Kyrgzystan, focusing on why bilingual education can be useful in solving linguistic tension in Kyrgzystan and which organizational questions must be considered to make bilingual education effective. The paper begins by examining and refuting common…

Korth, Britta

426

McLuhan: Pro and Con.  

ERIC Educational Resources Information Center

Twenty-one critical essays on the ideas and works of Marshall McLuhan are offered in this review. In the course of the essays, McLuhan is characterized alternately as a genius, an extrapolator, and an oracle; a defender of the choice of choicelessness; a generalizer who rearranges, misinterprets, and misreads the facts to support his theses; an…

Rosenthal, Raymond, Ed.

427

I-ConFIRM Steering Committee  

Cancer.gov

Skip to Main Content at the National Institutes of Health | www.cancer.gov Epidemiology and Genomics Research In NCI's Division of Cancer Control and Population Sciences Menu Search EGRP Site: EGRP Home About the Program Mission & Vision Organizational

428

Static Con dentiality Enforcement for Distributed Programs ?  

E-print Network

ucken, Germany, E-mail: mantel@dfki.de In Proceedings of the 9th Static Analysis Symposium, Madrid, Spain;dential data, but merely observing the presence of a mes- sage on a channel for encrypted traÃ?c may leak). These leaks might be intended (when planted by a Trojan-horse program) or unintended (when c

Sabelfeld, Andrei

429

Roofing with Urethane: Pro and Con.  

ERIC Educational Resources Information Center

Gerald Scott's favorable evaluation of the foamed polyurethane roofing system is based on experiences with 55 buildings at Texas A & M. Michael Kinzer, an architect at Colorado State University, disagrees and claims that the system is difficult to install and maintain, and the cost prohibitive. (MLF)

Kinzer, Michael; Scott, Gerald P.E.

1981-01-01

430

Endoscopist-Directed Propofol: Pros and Cons  

PubMed Central

Concerns about the safety of endoscopist-directed propofol (EDP) have been voiced that propofol should be given only by healthcare professionals trained in the administration of general anesthesia. Here we discuss the safety and drawbacks of EDP for routine endoscopic procedures. Currently, both diagnostic and therapeutic endoscopy are well tolerated and accepted by both patients and endoscopists due to the application of sedation in most clinics worldwide. Accordingly, propofol use is increasing in many countries. It is crucial for endoscopists to be very familiar with the use of propofol or a combination of drugs. However, the controversy regarding the administration of sedation by an endoscopist or an anesthesiologist continues. Until now, there have been no randomized control trials comparing sedation induced by propofol administered by an endoscopist or by an anesthesiologist. It might be difficult to perform this kind of study. For the convenience and safety of sedative endoscopy, it would be important that EDP be generally applied to endoscopic procedures, and for more safety, an anesthesiologist may automatically take care of particular patients at high risk of suffering from propofol side effects. PMID:24765594

Kim, Eun Hye

2014-01-01

431

Endoscopist-directed propofol: pros and cons.  

PubMed

Concerns about the safety of endoscopist-directed propofol (EDP) have been voiced that propofol should be given only by healthcare professionals trained in the administration of general anesthesia. Here we discuss the safety and drawbacks of EDP for routine endoscopic procedures. Currently, both diagnostic and therapeutic endoscopy are well tolerated and accepted by both patients and endoscopists due to the application of sedation in most clinics worldwide. Accordingly, propofol use is increasing in many countries. It is crucial for endoscopists to be very familiar with the use of propofol or a combination of drugs. However, the controversy regarding the administration of sedation by an endoscopist or an anesthesiologist continues. Until now, there have been no randomized control trials comparing sedation induced by propofol administered by an endoscopist or by an anesthesiologist. It might be difficult to perform this kind of study. For the convenience and safety of sedative endoscopy, it would be important that EDP be generally applied to endoscopic procedures, and for more safety, an anesthesiologist may automatically take care of particular patients at high risk of suffering from propofol side effects. PMID:24765594

Kim, Eun Hye; Lee, Sang Kil

2014-03-01

432

Communicating Genetic Risk: Pros, Cons, and Counsel  

Microsoft Academic Search

Shortly before his death in 1995, Kenneth B. Schwartz, a cancer patient at Massachusetts General Hospital (MGH), founded The Kenneth B. Schwartz Center at MGH. The Schwartz Center is a non-profit organization dedicated to supporting and advancing com- passionate health care delivery, which provides hope to the patient, support to caregivers, and encourages the healing process. The center sponsors the

RICHARD T. P ENSON; MICHAEL V. S EIDEN; KRISTEN M. SHANNON; MARCIE L. LUBRATOVICH; MARIA ROCHE; BRUCE A. CHABNER; THOMAS J. LYNCH; Schwartz Center Rounds

433

ORNL/CON-224 Energy Division  

E-print Network

.................................. 3 4. DESCRIPTION OF SUMMARY FORMAT ............................. 4 5. ELECTRIC VAPOR COMPRESSION ....................................... 114 6.1 Dynamic Vapor Compression Systems ....... ...................... 114 6.2 Chemical ............................................... 223 9. NOVEL HEAT PUMP CYCLES ............ ........................... 228 10. CROSSCUTTING PROJECTS

Oak Ridge National Laboratory

434

CON TITOLO DI STUDIO CONSEGUITO IN ITALIA  

E-print Network

ITALIANO O STUDENTE U.E. - titolo accademico: il conseguimento del titolo accademico in Italia può essere Consolato Italiano) su carta intestata completa di relativo timbro in originale; - traduzione ufficiale del Rappresentanza Italiana all'estero competente per territorio (Ambasciata Italiana o Consolato Italiano); - titolo

435

Incentives for organ donation: pros and cons.  

PubMed

Altruism still remains the main principle of organ donation worldwide. However, since the current practices has not met the demand for organs, new strategies should be found to encourage organ donation. Implementation of financial incentives in transplantation is a matter of debate among experts in the fields of transplantation, ethics, law, and economics. It should be acknowledged that donors incur many expenses while participating in the transplant process, which seems unfair. Various forms of incentives have been suggested and are currently used worldwide. This article describes current attitudes toward incentives for in transplantation used in different countries, arguing in favor as well as against them. PMID:22841275

Chkhotua, A

2012-01-01

436

¿Quién puede comunicarse con el CIS?  

Cancer.gov

El Servicio de Información sobre el Cáncer del NCI puede ayudarle si usted es un paciente o superviviente de cáncer, un familiar o un amigo preocupado, un proveedor de cuidados médicos o una persona que de algún modo ha sido afectada por el cáncer.

437

Economic Value Added: Pros and Cons  

Microsoft Academic Search

In times of uncertainty and crisis the performance measurement instruments should be reanalyzed. Thus, alongside the classic indicators of performance, in business financial analysis can be used modern indicators which offer a greater flexibility and efficiency. Such a measurement indicator for financial results closely correlated with the requirement of maximizing shareholder wealth is the Economic Value Added (EVA). The economic

Laura VASILESCU; Ana POPA

2011-01-01

438

The pros and cons of code validation  

NASA Technical Reports Server (NTRS)

Computational and wind tunnel error sources are examined and quantified using specific calculations of experimental data, and a substantial comparison of theoretical and experimental results, or a code validation, is discussed. Wind tunnel error sources considered include wall interference, sting effects, Reynolds number effects, flow quality and transition, and instrumentation such as strain gage balances, electronically scanned pressure systems, hot film gages, hot wire anemometers, and laser velocimeters. Computational error sources include math model equation sets, the solution algorithm, artificial viscosity/dissipation, boundary conditions, the uniqueness of solutions, grid resolution, turbulence modeling, and Reynolds number effects. It is concluded that, although improvements in theory are being made more quickly than in experiments, wind tunnel research has the advantage of the more realistic transition process of a right turbulence model in a free-transition test.

Bobbitt, Percy J.

1988-01-01

439

erators with general and specific information con-  

E-print Network

- able to support pathogenic microorganism growth or toxin formation, or garlic-in- oil mixtures Are Not Allowed? Fresh or dried meat or meat products includ- ing jerky Canned fruits, vegetables, vegetable butters, flavored oils, hummus, garlic dip, salsas etc. Fish or shellfish products Canned pickled products

Jawitz, James W.

440

erators with general and specific information con-  

E-print Network

pathogenic microorganism growth or toxin formation, or garlic-in- oil mixtures that are not modified in a way? Fresh or dried meat or meat products includ- ing jerky Canned fruits, vegetables, vegetable butters, flavored oils, hummus, garlic dip, salsas etc. Fish or shellfish products Canned pickled products

Jawitz, James W.

441

Vacuum assist: angel or demon CON.  

PubMed

Vacuum-assisted venous drainage (VAVD) to enhance venous return during cardiopulmonary bypass (CPB) was described as early as 1958 but was not widely used until the late 1990s. VAVD was initially used to facilitate the use of smaller cannulas with ministernotomy but was increasingly used to allow reduction in CPB circuit size while maintaining CPB flow rates. This innovation was made without planned consideration to CPB circuit design, most critically that of the venous reservoir. Clinical reports of prime reduction facilitated by VAVD in both adult and pediatric CPB were associated with reduced nadir hematocrit and rates of transfusion that encouraged the proliferation of VAVD in CPB. Concomitantly, investigators have reported both in vitro and in vivo significantly increased arterial emboli associated with the use of VAVD, mostly related to accelerated venous air entrainment. In vitro studies continue to confirm this association and likely underestimate the resulting embolic load as a result of flawed study design. While the evidence for VAVD is equivocal, our understanding of the clinical impact of gaseous microemboli in CPB is similarly limited, most likely confined to blood-brain barrier disruption. It is only after two decades that CPB component design is receiving serious attention in terms of air handling. The ethics of innovation in the field of CPB warrant careful consideration. The application of VAVD is not without consequence. PMID:23930383

Willcox, Timothy W

2013-06-01

442

The Pros and Cons of Cyberspying  

Microsoft Academic Search

The emergence of computers has only accelerated various transitions and added new directions to where the world is heading. Nowadays, such practices as e-commerce, e-government, and e-learning are commonplace. For many of us, it's almost impossible to imagine our lives without email. As the world evolves, we must embrace change and clearly understand the associated dangers. For instance, children have

Maria Ganzha

2005-01-01

443

Investigaccion-accion en la sala de clases sobre las creencias de la cultura de la ciencia de un grupo de estudiantes universitarios y su relacion reciproca con el aprendizaje de las ciencias biologicas  

NASA Astrophysics Data System (ADS)

La investigacion---accion que se llevo a cabo en la sala de clases tenia como punto de partida las creencias de la cultura de la ciencia de un grupo de estudiantes universitarios para luego examinar sus implicaciones en el proceso de aprendizaje de las Ciencias Biologicas. ¿Que se supone que hagan las creencias en relacion con el aprendizaje? ¿En que consiste incorporar este aspecto a la practica educativa universitaria? Utilizando el modelo de Kemmis y McTaggart (1987) la investigacion-accion se planteo como un proceso dinamico en cuatro momentos en espiral constituidos por la planificacion, la accion, la observacion y la reflexion. Cada una de las fases tuvo una intencion retrospectiva y prospectiva formando una espiral de autorreflexion del conocimiento y la accion. Se llevaron a cabo audio grabaciones en clases y analisis de documentos. Ademas, la profesora-investigadora hizo un portafolio para reflexionar sobre las creencias de la cultura de la ciencia que tienen los estudiantes y las creencias del aprendizaje que tiene la profesora y sobre como la comprension de estos elementos ayudo a mejorar su practica educativa a traves del tiempo. Los resultados obtenidos apuntan a que las creencias de la cultura de la ciencia que tiene el grupo de estudiantes son diversas. Ellos si creen que la ciencia tiene una cultura la cual describieron como: complicada y desconocida que evoluciona constantemente, que es un conjunto de metodos, que es altamente tecnologica, que resuelve problemas de salud, ayuda a interpretar la realidad del mundo que los rodea y su origen y que existen unas intersecciones entre la ciencia y el poder. Sobre las creencias del proceso de aprendizaje de la profesora-investigadora, estas senalan que el modelaje de actores, la vision de la academia que tiene ella asi como la participacion y negociacion entre todos los involucrados en el proceso educativo, son factores que inciden en el proceso de aprendizaje.

Cordova-Santiago, Lizzette Astrid

444

The nature of the Ailao Shan-Red River (ASRR) shear zone: Constraints from structural, microstructural and fabric analyses of metamorphic rocks from the Diancang Shan, Ailao Shan and Day Nui Con Voi massifs  

NASA Astrophysics Data System (ADS)

The structural geology, timing of shearing, and tectonic implications of the ASRR shear zone, one of the most striking lineaments in Southeast Asia, have been the topics of extensive studies over the past few decades. The Xuelong Shan (XLS), Diancang Shan (DCS), Ailao Shan (ALS) and Day Nui Con Voi (DNCV) metamorphic massifs along the shear zone have preserved important information on its structural and tectonic evolution. Our field structural analysis, detailed microstructural and fabric analysis, as well as the quartz, sillimanite and garnet fabric studies of the sheared rocks from the massifs demonstrate the dominant roles of three deformation episodes during Cenozoic tectonic evolution in the shear zone. Among the contrasting structural and microstructural associations in the shear zone, D2 structures, which were formed at the brittle to ductile transition during large-scale left-lateral shearing in the second deformation episode, predominate over the structural styles of the other two deformation episodes. Discrete micro-shear zones with intensive grain size reduction compose the characteristic structural style of D2 deformation. In addition, several types of folds (early shearing folds, F21, and late-shearing folds, F22) were formed in the sheared rocks, including discrete to distributed mylonitic foliation, stretching lineation and shear fabrics (e.g., mica fish, domino structures, as well as sigma and delta fabrics). A sequence of microstructures from syn-kinematic magmatic flow, high-temperature solid-state deformation, to brittle-ductile shearing is well-preserved in the syn-kinematic leucocratic intrusions. Deformation structures from the first episode (D1) are characterized by F1 folds and distributed foliations (S1) in rocks due to pure shearing at high temperatures. They are preserved in weakly sheared (D2) rocks along the eastern margin of the ALS belt or in certain low-strain tectonic enclaves within the shear zone. Furthermore, semi-brittle deformation structures, such as hot striae and discrete retrogression zones, are attributed to normal-slip shearing in the third deformation episode (D3), which was probably locally active, along the eastern flank of the DCS range, for example. There are four quartz c-axis fabric patterns in the mylonitic rocks, including type A point maxima, type B Y point maxima with crossed girdles superimposition, type C quadrant maxima, as well as type D point and quadrant maxima combination. They are consistent with microscopic observations of microstructures of high-temperature pure shearing, low-temperature simple shearing and their superimposition. Integrated microstructural analysis and fabric thermometer studies provide information on both high temperature (up to 750 °C) and dominant low-temperature (300-600 °C) deformations of quartz grains in different rock types. Sillimanite and garnet fabrics, especially the latter, were primarily formed at the peak metamorphism during high-temperature pure shearing. The above structural, microstructural and fabric associations were generated in the tectonic framework of the Indian-Eurasian collision. The low-temperature microstructures and fabrics are attributed to left-lateral shearing along the ASRR shear zone from 27 to 21 Ma during the southeastward extrusion of the Indochina block, which postdated high-temperature deformation at the peak metamorphism during the collision.

Liu, Junlai; Tang, Yuan; Tran, My-Dung; Cao, Shuyun; Zhao, Li; Zhang, Zhaochong; Zhao, Zhidan; Chen, Wen

2012-03-01

445

Debate: Does genetic information in humans help us treat patients? PRO--genetic information in humans helps us treat patients. CON--genetic information does not help at all.  

PubMed

PRO: In the past decade, genotyping has started to help the neurologic practitioner treat patients with three types of epilepsy causing mutations, namely (1) SCN1A, a sodium channel gene mutated in Dravet's sporadic severe myoclonic epilepsy of infancy (SMEI and SMEB); (2) laforin (dual specificity protein phosphatase) and malin (ubiquitin E3 ligase) in Lafora progressive myoclonic epilepsy (PME); and (3) cystatin B in Unverricht-Lundborg type of PME. Laforin, malin, and cystatin B are non-ion channel gene mutations that cause PME. Genotyping ensures accurate diagnosis, helps treatment and genetic counseling, psychological and social help for patients and families, and directs families to organizations devoted to finding cures for specific epilepsy diseases. In SCN1A and cystatin B mutations, treatment with sodium channel blockers (phenytoin, carbamazepine, oxcarbazepine, lamotrigine) should be avoided. Because of early and correct diagnosis by genotyping of SCN1A mutations, the avoidance of sodium channel blockers, and aggressive treatment of prolonged convulsive status, there is hope that Dravet's syndrome may not be as severe as observed in all past reports. Genotyping also identifies nonsense mutations in Lafora PME. Nonsense mutations can be corrected by premature stop codon readthrough drugs such as gentamicin. The community practitioner together with epilepsy specialists in PME can work together and acquire gentamicin (Barton-Davis et al., 1999) for "compassionate use" in Lafora PME, a generalized lysosome multiorgan storage disorder that is invariably fatal. In Unverricht-Lundborg PME, new cohorts with genotyped cystatin B mutations have led to the chronic use of antioxidant N-acetylcysteine and combination valproate clobazam or clonazepam plus antimyoclonic drugs topiramate, zonisamide, piracetam, levetiracetam, or brivaracetam. These cohorts have minimal ataxia and no dementia, questioning whether the syndrome is truly progressive. In conclusion, not only is genotyping a prerequisite in the diagnosis of Dravet's syndrome and the progressive myoclonus epilepsies, but it also helps us choose the correct antiepileptic drugs to treat seizures in Dravet's syndrome and Unverricht-Lundborg PME. Genotyping also portends a brighter future, helping us to reassess the true course, severity, and progressive nature of Dravet's syndrome and Unverricht-Lundborg PME and helping us craft a future curative treatment for Dravet's syndrome and Lafora disease. Without the genotyping diagnosis of epilepsy causing mutations we are stuck with imprecise diagnosis and symptomatic treatment of seizures. CON: Genotyping of epilepsy may help to better understand the genetics of epilepsy, to establish an etiology in a patient with epilepsy, to provide genetic counseling, and to confirm a clinical diagnosis. However, critical analysis reveals that genotyping does not contribute to an improved treatment for the patients. In order to improve treatment, genotyping would have to (1) improve our ability to select the drug of choice for a given epilepsy or epileptic syndrome; (2) improve our ability to predict the individual risk of adverse reactions to certain drugs; (3) improve our ability to avoid unnecessary treatments or treatments that could aggravate seizures. Many example illustrate the lack of impact of genetic information on the treatment outcome: we do not treat Dravet syndrome more successfully since SCN1A testing became available; we do not treat Lafora disease more successfully since testing for laforin and malin became available; we do not need to know the genetic nature of Unverricht-Lundborg disease or test for the cystatin B mutation in order to select or avoid certain drugs; we do not treat Rett syndrome more successfully since MECP2 testing became available; we do not treat JME more successfully since we know its genetic origin; we do not treat autosomal dominant nocturnal frontal lobe epilepsy more successfully since we know its genetic origin and can test for its mutation. The clinical characteristics as well as the

Delgado-Escueta, Antonio V; Bourgeois, Blaise F D

2008-12-01

446

Science Drivers for Con-XScience Drivers for Con-X Presented by  

E-print Network

and their effect on galaxy formation Dark Matter and Dark Energy Use clusters of galaxies to trace the locations of Dark Matter and as independent probes to constrain the amount and evolution of Dark Energy Search for the missing baryonic matter in the Cosmic Web Cycles of Matter and Energy Study dynamics of Cosmic Feedback

Garcia, Michael

447

Adopte MiPlato: con los alimentos con protenas, la clave est en la variedad.  

E-print Network

, chicken anutty Spoo ey ow to creat ree Protein otein foods ach... Plate poste me tags (o is key fridge 8. Obtain food models or pictures of Protein Foods: fish, chicken, pork, beef, eggs, seeds, nuts, seeds, nuts and eggs Food models or pictures of Protein Foods: fish, chicken, pork, beef, eggs, seeds

448

Right Hemisphere Dominance for Emotion Processing in Baboons  

ERIC Educational Resources Information Center

Asymmetries of emotional facial expressions in humans offer reliable indexes to infer brain lateralization and mostly revealed right hemisphere dominance. Studies concerned with oro-facial asymmetries in nonhuman primates largely showed a left-sided asymmetry in chimpanzees, marmosets and macaques. The presence of asymmetrical oro-facial…

Wallez, Catherine; Vauclair, Jacques

2011-01-01

449

Atomoxetine and Methylphenidate Treatment in Children with ADHD: The Efficacy, Tolerability and Effects on Executive Functions  

ERIC Educational Resources Information Center

The aim of this study was to compare the safety, efficacy, tolerability, and the effects of atomoxetine and OROS-MPH on executive functions in children with ADHD. This study was an open-label study that only included two medication groups. Children were randomized to open-label atomoxetine or OROS-MPH for 12 weeks. Primary efficacy measures were…

Yildiz, Ozlem; Sismanlar, Sahika G.; Memik, Nursu Cakin; Karakaya, Isik; Agaoglu, Belma

2011-01-01

450

Same Noses, Different Nasalance Scores: Data from Normal Subjects and Cleft Palate Speakers for Three Systems for Nasalance Analysis  

ERIC Educational Resources Information Center

Nasalance scores from the Nasometer, the NasalView and the OroNasal System were compared. The data was collected from 50 normal participants and 19 hypernasal patients with cleft palate. The Nasometer had the lowest nasalance scores for the non-nasal Zoo Passage and that the OroNasal System had the lowest nasalance scores for the Nasal Sentences.…

Bressmann, Tim; Klaiman, Paula; Fischbach, Simone

2006-01-01

451

Does Prolonged Therapy with a Long-Acting Stimulant Suppress Growth in Children with ADHD?  

ERIC Educational Resources Information Center

Objective: To investigate whether prolonged therapy with a long-acting stimulant affects growth in children with attention-deficit/hyperactivity disorder (ADHD). Method: One hundred seventy-eight children ages 6 to 13 years received OROS methylphenidate (OROS MPH, CONCERTA) for at least 21 months. Height and weight were measured monthly during the…

Spencer, Thomas J.; Faraone, Stephen V.; Biederman, Joseph; Lerner, Marc; Cooper, Kimberly M.; Zimmerman, Brenda

2006-01-01

452

Use of digital multispectral videography to assess seagrass distribution in San Quinti??n Bay, Baja California, Mexico [Uso de videografi??a multiespectral digital para evaluar la distributio??n del pasto marino en Bahi??a San Quinti??n, Baja California, Me??xico  

USGS Publications Warehouse

Apparent threats to the spatial distribution of seagrass in San Quinti??n Bay prompted us to make a detailed assessment of habitats in the bay. Six coastal habitats and three seagrass subclasses were delineated using airborne digital multispectral videography (DMSV), Eelgrass, Zostera marina, was the predominant seagrass and covered 40% (1949 ha) of the areal extent of the bay in 1999. Eelgrass grew over a wide range of tidal depths from about -3.0 in mean lower low water (MLLW) to about 1.0 m MLLW, but greatest spatial extent occurred in intertidal areas -0.6 m to 1.0 m MLLW. Exposed-continuous (i.e., high density) eelgrass was the most abundant habitat in the bay. Widgeongrass, Ruppia maritima, was the only other seagrass present and covered 3% (136 ha) of the areal extent of the entire bay. Widgeongrass grew in single species stands in the upper intertidal (??? 0.4 MLLW) and intermixed with eelgrass at lower tidal depths. Overall accuracy of the six habitat classes and three subclasses in the DMSV map was relatively high at 84%. Our detailed map of San Quintin Bay can be used in future change detection analyses to monitor the health of seagrasses in the bay.

Ward, D.H.; Tibbitts, T.L.; Morton, A.; Carrera-Gonzalez, E.; Kempka, R.

2004-01-01

453

Biochemical characterization of the eelgrass Zostera marina at its southern distribution limit in the North Pacific [Caracterizacio??n bioqui??mica del pasto marino Zostera marina en el li??mite sur de su distribucio??n en el Paci??fico Norte  

USGS Publications Warehouse

The eelgrass Zostera marina L. is distributed along the Baja California Peninsula (Mexico) where it is exposed to a wide range of irradiances and temperatures that could promote changes in its biochemical composition. Consequently, the objective of this study was to characterize the variations in the levels of chlorophyll, carbohydrates, proteins, fiber, ash and calories in the shoots of Z. marina from the north (San Quintin) and south (Ojo de Liebre and San Ignacio lagoons) of the peninsula. Temperature in the southern lagoons was 5-6??C higher than in the northern lagoon; likewise, in situ irradiance was two-fold greater in the south than in the north. As a result of the lower irradiance levels, the concentration of chlorophyll in the shoots of Z. marina was twice as high (1.7 mg gWW-1) in the northern lagoon than in the southern ones (0.8 mg gWW-1). Similar to chlorophyll levels, the concentration of soluble carbohydrates in the shoots was greater in the northern lagoon than in the southern ones, suggesting that the high levels of chlorophyll are enough to compensate for the low irradiance levels and to maintain a positive carbon balance at San Quintin. On the other hand, the levels of proteins in the shoots from the north of the peninsula were slightly lower than those from the southern populations. In general, these results suggest that the different environmental conditions to which Z. marina is exposed along the peninsula impact its biochemical composition.

Cabello-Pasini, A.; Muniz-Salazar, R.; Ward, D.H.

2004-01-01

454

Eficacia del tratamiento antinflamatorio comparado con antibiótico y placebo en pacientes con bronquitis aguda no complicada y expectoración purulenta. Ensayo clínico aleatorio controlado con placebo.  

E-print Network

??Aquesta tesi tenia per objectiu conèixer l'eficàcia del tractament antiinflamatori (ibuprofèn 500 mg/8h/10d) o antibiòtic (amoxicil•lina+àcid clavulànic 500/125 mg/8h/10d) comparat amb placebo en la resolució… (more)

Bayona Faro, Carolina

2014-01-01

455

15 CFR Supplement No. 3 to Part 744 - Countries Not Subject to Certain Nuclear End-Use Restrictions in § 744.2(a)  

Code of Federal Regulations, 2010 CFR

...Not Subject to Certain Nuclear End-Use Restrictions in § 744.2(a) Australia Austria Belgium Canada Denmark Finland France Germany Greece Iceland Ireland Italy (includes San Marino and Holy See) Japan Luxembourg...

2010-01-01

456

A review of "John Dryden: A Miscellany. And John Dryden (1631-1700): His Politics, His Plays, and His Poets." by Susan Green and Steven N. Zwicker eds. And Claude Rawson and Aaron Santesso eds.  

E-print Network

. San Marino, Cal.: Huntington Library, 2001. vii+255 pp. And Claude Rawson and Aaron Santesso, eds. John Dryden (1631-1700): His Politics, His Plays, and His Poets. Newark: University of Delaware Press, 2004. 301pp. Review by JEROME DONNELLY...

Jerome Donnelly

2005-01-01

457

78 FR 72979 - Bovine Spongiform Encephalopathy; Importation of Bovines and Bovine Products  

Federal Register 2010, 2011, 2012, 2013

...the Former Yugoslav Republic of Macedonia, Monaco, Norway, Oman, the Netherlands, Poland, Portugal, Romania, San Marino...the Former Yugoslav Republic of Macedonia, Monaco, Norway, Oman, the Netherlands, Poland, Portugal, Romania, San...

2013-12-04

458

9 CFR 94.24 - Restrictions on the importation of pork, pork products, and swine from the APHIS-defined European...  

...Ireland, Israel, Italy, Japan, Liechtenstein, Luxembourg, the Former Yugoslav Republic of Macedonia, Monaco, Norway, Oman, the Netherlands, Poland, Portugal, Romania, San Marino, Slovakia, Slovenia, Spain, Sweden, Switzerland, and the...

2014-01-01

459

9 CFR 95.4 - Restrictions on the importation of processed animal protein, offal, tankage, fat, glands, certain...  

...Ireland, Israel, Italy, Japan, Liechtenstein, Luxembourg, the Former Yugoslav Republic of Macedonia, Monaco, Norway, Oman, the Netherlands, Poland, Portugal, Romania, San Marino, Slovakia, Slovenia, Spain, Sweden, Switzerland, and the...

2014-01-01

460

Operación IceBridge: Explorando la Antártida - Duration: 3:04.  

NASA Video Gallery

Operación IceBridge es una misión aérea de la NASA dedicada a estudiar cambios en el hielo marino y terrestre en ambos polos del planeta. En octubre y noviembre de 2012, IceBridge completó su cuart...

461

Virus Research 188 (2014) 146154 Contents lists available at ScienceDirect  

E-print Network

for the in vitro selection of artificial ssDNA or RNA ligands, known as aptamers, which bind to targets through seafood fish throughout China and Southeast Asia (Marino et al., 2001). In recent years, however

Gray, Matthew

462

15 CFR Supplement No. 3 to Part 744 - Countries Not Subject to Certain Nuclear End-Use Restrictions in § 744.2(a)  

Code of Federal Regulations, 2013 CFR

...Restrictions in § 744.2(a) Australia Austria Belgium Canada Denmark Finland France Germany Greece Iceland Ireland Italy (includes San Marino and Holy See) Japan Luxembourg Netherlands New Zealand Norway...

2013-01-01

463

15 CFR Supplement No. 3 to Part 744 - Countries Not Subject to Certain Nuclear End-Use Restrictions in § 744.2(a)  

Code of Federal Regulations, 2012 CFR

...Restrictions in § 744.2(a) Australia Austria Belgium Canada Denmark Finland France Germany Greece Iceland Ireland Italy (includes San Marino and Holy See) Japan Luxembourg Netherlands New Zealand Norway...

2012-01-01

464

15 CFR Supplement No. 3 to Part 744 - Countries Not Subject to Certain Nuclear End-Use Restrictions in § 744.2(a)  

...Restrictions in § 744.2(a ) Australia Austria Belgium Canada Denmark Finland France Germany Greece Iceland Ireland Italy (includes San Marino and Holy See) Japan Luxembourg Netherlands New Zealand Norway...

2014-01-01

465

DCC -1 semestre de 2012 TC021 Mecnica Geral I -1 Semestre  

E-print Network

Dalledone Machado Turma B Miguel Frederico Hilgenberg Neto Turma C Marcos Antonio Marino Turma D Marco André Estruturas de Madeira Turma A Miguel Frederico Hilgenberg Neto TC058 Pontes e Estruturas Especiais Turma

Paraná, Universidade Federal do

466

Atomoxetine and methylphenidate treatment in children with ADHD: the efficacy, tolerability and effects on executive functions.  

PubMed

The aim of this study was to compare the safety, efficacy, tolerability, and the effects of atomoxetine and OROS-MPH on executive functions in children with ADHD. This study was an open-label study that only included two medication groups. Children were randomized to open-label atomoxetine or OROS-MPH for 12 weeks. Primary efficacy measures were T-DSM-IV-S, CGI-I and neuropsychological tests battery. Safety assessments included electrocardiogram, adverse events checklist and laboratory tests. According to the endpoint improvement scores of CGI and parents T-DSM-IV-S, treatment responses were not significantly different between the two study groups. OROS-MPH led to a significantly greater reduction in teacher T-DSM-IV-S scale scores. OROS-MPH was more effective than atomoxetine on Stroop-5 time and number of corrections. Significant decrease in the percentage of perseverative errors on WCST in the OROS-MPH group was seen (p = 0.005). The most frequently reported adverse events in the atomoxetine group were anorexia, nausea, nervousness, weight loss, abdominal pain, and somnolence. In the OROS-MPH group, patients most frequently reported anorexia, nervousness, insomnia, headache, nausea, and weight loss. When all these results are considered, although both drugs can be considered effective in ADHD treatment, more remarkable improvement is provided by OROS-MPH based on the rates across informant (i.e., teachers, clinicians) and neuropsychological evaluation. PMID:21165694

Yildiz, Ozlem; Sismanlar, Sahika G; Memik, Nursu Cakin; Karakaya, Isik; Agaoglu, Belma

2011-06-01

467

CADASIL: arteriopatía cerebral autonómica dominante con infartos subcorticales y leucoencefalopatía  

Microsoft Academic Search

CADASIL is a cerebrovascular autosomal dominant hereditary disease caused by a mutation of the Notch3 gene. Its principal clinical manifestations consist in migraine, recurrent cerebral ischemic episodes, dementia and neuropsychiatric disorders. It is characterized by accumulation of granular osmiophilic material (GOM) located in the middle layer of the small and median sized cerebral arteries. A clinical case is presented of

A. Palomeras i Vilches; A. Picas Jufresa; L. Ramió Torrentà; J. Cristóbal Buñuel Álvarez

2010-01-01

468

Clinical drawbacks of total lymphoid irradiation: the cons  

SciTech Connect

Success has been reported with use of total lymphoid irradiation (TLI) in organ transplant recipients and in patients with rheumatoid arthritis and other autoimmune diseases. In a well-conducted randomized double blind clinical trial, Cook et al have found that TLI was superior to sham irradiation of patients with multiple sclerosis (MS). However, it is clear from looking at this data that not all patients responded to TLI and that with time disease activity returned. Our own experience with TLI in two MS patients was very disappointing. Despite its apparent benefit in some conditions, considerable drawbacks are associated with TLI. These include high financial cost, unpleasant treatment-related side effects, and the possibility that more serious morbidity as well as mortality may be treatment-related. Furthermore, the optimum therapeutic regimen for TLI has not yet been established. Issues related to cumulative dose, dose per fraction, frequency of fractions, field of irradiation, and interaction with other therapies still need clarification. For these reasons we do not recommend TLI as a treatment for MS.

Myers, L.W.; Ellison, G.W.; Fahey, J.L.; Tesler, A.; Gottlieb, M.S.

1988-07-01

469

INEEL/CON-1999-343 October 1999  

E-print Network

between existing fusion experiment and fission test reactor availability. Present fusion experiments have a on Fusion Engineering Albuquerque, New Mexico October 25-28, 1999 #12;a. This work was prepared for the U. S. Department of Energy, Office of Fusion Energy Sciences, under the DOE Idaho Field Office contract number DE

California at Los Angeles, University of

470

RETENCION DE CROMO Y MERCURIO CON ZEOLITAS NATURALES Y SINTETICAS  

Microsoft Academic Search

La presencia de cationes de metales pesados en el agua crea problemas serios por sus efectos tóxicos sobre animales, plantas y sobre la salud humana. Como existe una gran variedad de procesos industriales que generan este tipo de contaminación, el control de la presencia de metales pesados en agua es difícil. Se ha usado, para algunos de ellos, técnicas de

Renán Arriagada; Rafael García; Ruby Cid

471

Montaje Experimental de Optica Adaptiva con Tecnología FPGA  

Microsoft Academic Search

An experimental platform based on FPGA devices, dedicated to implement active and adaptive optic software in HDL has been developed. The devel- oped assembly is the first of a series of works focused on this important area of instrumental astronomy. The exposed development is part of a Final Project of Electronic Engineering of the National University of Cordoba. FULL TEXT

F. Rodriguez Brizuela; J. P. Verasay; P. Recabarren

2010-01-01

472

Astrobiological Aspects of Mars and Human Presence: Pros and Cons  

PubMed Central

After the realization of the International Space Station, human exploratory missions to Moon or Mars, i.e. beyond low Earth orbit, are widely considered as the next logical step of peaceful cooperation in space on a global scale. Besides the human desire to extend the window of habitability, human exploratory missions are driven by several aspects of science, technology, culture and economy. Mars is currently considered as a major target in the search for life beyond the Earth. Understanding the history of water on Mars appears to be one of the clues to the puzzle on the probability of life on Mars. On Earth microorganisms have flourished for more than 3.5 Ga and have developed strategies to cope with so-called extreme conditions (e.g., hot vents, permafrost, subsurface regions, rocks or salt crystals). Therefore, in search for life on Mars, microorganisms are the most likely candidates for a putative biota on Mars and the search for morphological or chemical signatures of life or its relics is one of the primary and most exciting goals of Mars exploration. The presence of humans on the surface of Mars will substantially increase this research potential, e.g., by supporting deep subsurface drilling and by allowing intellectual collection and sophisticated in situ analysis of samples of astrobiological interest. On the other hand, such long-duration missions beyond LEO will add a new dimension to human space flight, concerning the distance of travel, the radiation environment, the gravity levels, the duration of the mission, and the level of confinement and isolation the crew will be exposed to. This will raise the significance of several health issues, above all radiation protection, gravity related effects as well as psychological issues. Furthermore, the import of internal and external microorganisms inevitably accompanying any human mission to Mars, or brought purposely to Mars as part of a bioregenerative life support system needs careful consideration with regard to planetary protection issues. Therefore, before planning any human exploratory mission, the critical issues concerning human health and wellbeing as well as protection of Mars in its pristine condition need to be investigated. PMID:19048093

Horneck, G

2008-01-01

473

Pros and cons of organ shielding for CT imaging.  

PubMed

With the increased importance of CT radiation dose to health care providers, patients and the general public, there is an increased responsibility to minimize patient dose effectively. Bismuth shields offer a simple strategy to reduce dose to certain anterior radiosensitive organs such as breasts and eyes. However, in order to reduce organ dose they must be used properly; improper use can lead to an actual increase in the patient dose. They also create a proportional increase in image noise in the section of the body adjacent to the shield and further reduce the quantitative precision of CT numbers. In addition, shielding can degrade the overall efficiency (by an order of approximately 10%) of the imaging process, reducing the theoretical image quality that can be expected from a certain level of patient dose. However, in spite of their significant disadvantages, there are certain clinical situations and practice considerations that provide qualified justification for their continued use. PMID:25304710

Samei, Ehsan

2014-10-01

474

ORNL/CON-460 The Evaluation of a 4000-Home  

E-print Network

..........................................................................................6 1.4.1 Data Collection 1.4.5 Analysis of Maintenance Costs ................................................................................................8 2. METHODOLOGY AND CALCULATION OF ENERGY SAVINGS.................................9 2.1 Field Data

Oak Ridge National Laboratory

475

Dial 3111 for Emergencies on Campus pecial emergency telephones con-  

E-print Network

Safety, with the assistance of the New Jersey College University Public Safety Association, has developed should provide: · The location of the call. · His or her identity. · The type of assistance needed alert, Public Safety will follow the U.S. Department of Homeland Security's procedures as necessary

476

The Prose of Blogging (and a Few Cons, Too)  

ERIC Educational Resources Information Center

"Blogging for the sake of blogging is fine, but what is the value added?" That's a question educational blogging advocates are now coming around to answer, and the value they're finding may seem preposterous to those who associate blogging with barely literate loudmouths and cyber predators. Can this often belligerent wasteland of poor punctuation…

Ramaswami, Rama

2008-01-01

477

Las personas con diabetes deben lograr un balance entre los  

E-print Network

en un lado del plato y los alimentos bajos en carbohidratos al otro lado. Karen Halderson, MPH, RD bajos en carbohidratos, manteniendo cada uno en su propio lado del plato o de la mesa. Comer vegetales en diferentes lados de su plato y ver si su plato está "balanceado". Sin embargo, muchas veces

478

El dramaturgo de Los olvidados: Entrevista con Juan Radrigán  

E-print Network

, "como el cielo, la piedad y los perros." Y quien mejor que él lo sabe. Radrigán es a los pobres lo que Egon Wolff, Vodanovic, Cuadra, son a la burguesía y clase media chilenas en la dramaturgia nacional. Todos ellos son fieles al medio que representan... actores deben aportar la caracterización. Ni siquiera maquillaje admite. En Hechos consumados hubo que hacer una excepción, pues una de las actrices era rubia y muy llamativa—para no decir hermosa—y debía desempeñar el papel de una vagabunda. Hubo que...

Bravo-Elizondo, Pedro

1983-10-01

479

Formal Veri cation of Con ict Detection Ricky Butler1  

E-print Network

Langley Research Center Hampton VA 23681-2199 munoz@icase.edu Abstract. Safety assessment of new air tra c , and Cesar Mu~noz3 1 Assessment Technology Branch, Mail Stop 130, NASA Langley Research Center Hampton, VA for aircraft separation is partially or completely moved from a centralized air tra c controller

Butler, Ricky W.

480

Pros and Cons of Paper and Electronic Surveys  

ERIC Educational Resources Information Center

This chapter describes the different types of paper and electronic surveys currently available and their costs and benefits in terms of equipment and printing costs, demands on staff time, and ease of use.

Porter, Stephen R.

2004-01-01

481

Learners or Participants? The Pros and Cons of "Lifelong Learning"  

ERIC Educational Resources Information Center

Whereas adult education used to be the preferred concept for those studying adult music-making, there is now an increasing trend away from this and towards lifelong learning. Uncritically adopting government lifelong learning discourses, however, blurs the line between educational ideals and political ones. Although there may be merit in the…

Mantie, Roger

2012-01-01

482

Pros and cons in the search for extraterrestrial intelligence  

Microsoft Academic Search

I propose a new term, ‘galactic organism with distinct intelligence’, for the extraterrestrial forms, with which humans can make contact. This is because, among the three existing terms: (a) ‘the search for extraterrestrial intelligence#x02019; ‘excludes biology and is inelegant#x02019; (b) ‘extraterrestrial#x02019; does not distinguish between the micro-organisms and highly-evolved intelligent life-forms; and (c) 'unidentified flying object' projects a sense of

S. Sri Kantha

1996-01-01

483

Astronomia solare e ottica con il foro stenopeico  

NASA Astrophysics Data System (ADS)

The observation of the Sun with pinholes was started in Florence's Cathedral in 1475, and in Ulugh Beg observatory in Samarcand in 1424-29, well before the invention of the telescope, for measuring the solar position and the variation of the obliquity of the Earth's axis. Later, with Kepler, pinholes' telescopes were used to follow the solar spots when the telescopes made by Galileo were not available. The use of pinholes in positional solar astrometry continued successfully up to 1800 in some great Italian and French Churches. Nowadays by using pinholes it is possible to show the principles of positional astronomy and imaging to students with instruments very easy to be built at almost no cost. The concepts of focal length, best focus, angular resolution, atmospheric seeing and atmospheric transmittance can be verified with such simple devices. Such pinhole telescopes have been built by primary-school students at the Astronomical Observatory dedicated to the Pope astronomer Sylvester II, located in Bukowiec, Poland, which is at its third year of activity. The largest solar spots have been observed clearly with these instruments, demonstrating the principles discussed in this presentation. The light cast by one of this devices with 70 m of focal length and 1 cm of diameter has permitted to repeat the experiences on the diffraction of the light, made in 1648 by the Jesuits Riccioli and Grimaldi.

Sigismondi, Costantino

484

University Facilities Planning & Con-Project Manager; Bahar Armaghani  

E-print Network

% recycled rubber tires Indoor Environmental Quality Carbon Dioxide monitoring Good housekeeping during conditions. Materials and Resources Building reuse, maintain 75% of existing shell Waste management plan

Slatton, Clint

485

Introduction The study attempts to quantify several con-  

E-print Network

was observed in the way that supervisors and hourly employees see the dominant cul- tures at the workplace- pany is related to the dominant climate in the workplace. A creative climate is characterized by high. Systems where open communication is the norm yield better outcomes and result in higher morale than more

486

Travellers' diarrhoea - pros and cons of different prophylactic measures.  

PubMed

Travellers' diarrhoea is the most likely cause for disturbing travel arrangements. At an average, 30-40% of tourists are concerned, depending on the travel destination. Due to the high impact on the travellers' health this topic is still of utmost importance in travel medicine. A wide spectrum of enteropathogens can be accountable, with enterotoxigenic Escherichia coli being the major causing pathogen among other bacteria, parasites and viruses. Here we discuss advantages and disadvantages of different prophylactic measures against travellers' diarrhoea. The effectiveness but also the relevance of hygiene education, vaccination and antibiotic or probiotic application will be discussed in the context of the travellers' different risk profiles. PMID:19915810

Wagner, Angelika; Wiedermann, Ursula

2009-10-01

487

Pro/con ethics debate: When is dead really dead?  

PubMed Central

Contemporary intensive care unit (ICU) medicine has complicated the issue of what constitutes death in a life support environment. Not only is the distinction between sapient life and prolongation of vital signs blurred but the concept of death itself has been made more complex. The demand for organs to facilitate transplantation promotes a strong incentive to define clinical death in a manner that most effectively supplies that demand. We consider the problem of defining death in the ICU as a function of viable organ availability for transplantation PMID:16356234

Whetstine, Leslie; Streat, Stephen; Darwin, Mike; Crippen, David

2005-01-01

488

Examinando algunas disyuntivas de política económica con un modelo estructural  

Microsoft Academic Search

En este documento se intenta dar respuesta, mediante el empleo de un modelo estructural, a tres tipos de interrogantes: las implicancias de una mejora en los procesos productivos, los efectos de un cambio en los niveles de endeudamiento público y los costos en términos del producto de un cambio en la tasa de inflación objetivo. Las simulaciones que arroja el

Luis Gonzalo Llosa Velásquez

2004-01-01

489

Experimentar con un cohete de plasma - Duration: 2:50.  

NASA Video Gallery

El Dr. Franklin Chang-Díaz, el primer astronauta hispano de la NASA, es actualmente el presidente y CEO de Ad Astra Rocket Company, la empresa que desarrolla el nuevo cohete de plasma VASIMR. Apren...

490

9 CFR 319.300 - Chili con carne.  

...Mechanically Separated (Species) may be used in accordance with § 319.6. Head meat, cheek meat, and heart meat exclusive of the heart cap may be used to the extent of 25 percent of the meat ingredients under specific declaration on the...

2014-01-01

491

9 CFR 319.301 - Chili con carne with beans.  

...Mechanically Separated (Species) may be used in accordance with § 319.6. Head meat, cheek meat, or heart meat exclusive of the heart cap may be used to the extent of 25 percent of the meat ingredients, and its presence shall be...

2014-01-01

492

9 CFR 319.300 - Chili con carne.  

Code of Federal Regulations, 2011 CFR

...Mechanically Separated (Species) may be used in accordance with § 319.6. Head meat, cheek meat, and heart meat exclusive of the heart cap may be used to the extent of 25 percent of the meat ingredients under specific declaration on the...

2011-01-01

493

Control de la congestión vehicular en Bogotá con herramientas microeconómicas  

Microsoft Academic Search

A partir de un diagnóstico de la congestión que las causas del problema van más allá de un exceso de vehículos y una falta de vías. Se estudian cuatro alternativas para reducir la congestión: la restricción de circulación por placas, el cobro por entrar en una zona de la ciudad, una política de parqueo y la creación de un nuevo

Arturo Ardila Gómez

1995-01-01

494

Encompassing Sexual Medicine within Psychiatry: Pros and Cons  

ERIC Educational Resources Information Center

Objective: This article examines the positive and negative aspects of psychiatry encompassing sexual medicine within its purview. Methods: MEDLINE searches for the period between 1980 to the present were performed with the terms "psychiatry," "sexual medicine," and "sexual dysfunction." In addition, sexual medicine texts were reviewed for chapters…

Segraves, Robert Taylor

2010-01-01

495

here's no end to the number of scams con-  

E-print Network

stress man- agement isn't about relaxation, better eat- ing, getting a massage, or practicing yoga. The best stress management strategy might be a better way to solve a stressful problem. Here's a problem-solving for- mula to apply to the root of a problem you face that causes stress: 1) Define the problem; 2

Kim, Duck O.

496

Strategic vision or strategic con?: Rhetoric or reality?  

PubMed

Major companies devote considerable effort to communicating corporate visions and missions. Yet three recent surveys suggest that much of this effort has been counter-productive. A gap has emerged between rhetoric and reality. Arenas of confrontation have arisen between directors and managers, head offices and business units, holding companies and their subsidiaries, and between specialists and generalists. A widespread desire for corporate transformation is not matched by understanding of how to bring it about. The lack of top management commitment and of communication skills are major barriers to change. More competent directors and more effective boards are needed. The article suggests key roles for the chairman and the chief executive. It examines how best to share a compelling vision, and identifies a requirement for new attitudes and approaches to communication. PMID:10118382

Coulson-Thomas, C

1992-02-01

497

Astrobiological aspects of Mars and human presence: pros and cons.  

PubMed

After the realization of the International Space Station, human exploratory missions to Moon or Mars, i.e. beyond low Earth orbit, are widely considered as the next logical step of peaceful cooperation in space on a global scale. Besides the human desire to extend the window of habitability, human exploratory missions are driven by several aspects of science, technology, culture and economy. Mars is currently considered as a major target in the search for life beyond the Earth. Understanding the history of water on Mars appears to be one of the clues to the puzzle on the probability of life on Mars. On Earth microorganisms have flourished for more than 3.5 Ga and have developed strategies to cope with so-called extreme conditions (e.g., hot vents, permafrost, subsurface regions, rocks or salt crystals). Therefore, in search for life on Mars, microorganisms are the most likely candidates for a putative biota on Mars and the search for morphological or chemical signatures of life or its relics is one of the primary and most exciting goals of Mars exploration. The presence of humans on the surface of Mars will substantially increase this research potential, e.g., by supporting deep subsurface drilling and by allowing intellectual collection and sophisticated in situ analysis of samples of astrobiological interest. On the other hand, such long-duration missions beyond LEO will add a new dimension to human space flight, concerning the distance of travel, the radiation environment, the gravity levels, the duration of the mission, and the level of confinement and isolation the crew will be exposed to. This will raise the significance of several health issues, above all radiation protection, gravity related effects as well as psychological issues. Furthermore, the import of internal and external microorganisms inevitably accompanying any human mission to Mars, or brought purposely to Mars as part of a bioregenerative life support system needs careful consideration with regard to planetary protection issues. Therefore, before planning any human exploratory mission, the critical issues concerning human health and wellbeing as well as protection of Mars in its pristine condition need to be investigated. PMID:19048093

Horneck, G

2008-08-01

498

The pros and cons of using irradiation for phytosanitary treatments  

Technology Transfer Automated Retrieval System (TEKTRAN)

Irradiation is increasingly being used as a phytosanitary treatment in Asia, Australia and the Americas, but the process is not being used or promoted in the European Union. However, under the current regulatory framework it is possible for food commodities irradiated to prevent the spread of alien...

499

iCons, 2011 Top 10 Scientific Achievements: Lesson Plan  

E-print Network

by negative (i.e. what's /not/ scientific). Example to help clarify might be Fire / Internal Combustion Engine.e. what's /not/ scientific). Example to help clarify might be Fire / Internal Combustion Engine

Auerbach, Scott M.

500

Modelli decisionali della dipendenza: simulazioni del In collaborazione con  

E-print Network

of addiction, delimited in Figure 1 by vertical dotted lines: controlled drug use, drug abuse, drug addiction, post-addiction stage. 3 #12;controlled use post-addiction stage drug addiction drug abuse Figure 1 of drug addiction is characterized by the condition of the preceding stage to which is added

Mocenni, Chiara