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Sample records for medhat hussainov alexander

  1. Alexander I. Ignatowski

    PubMed Central

    Konstantinov, Igor E.; Jankovic, Gradimir M.

    2013-01-01

    In 1908, Alexander I. Ignatowski (1875–1955) published his pioneering work that first revealed a relationship between cholesterol-rich food and experimental atherosclerosis. This early experimental work paved a way to the metabolic study of the mechanism of atherosclerosis. Herein, we present a brief account of Ignatowski's work and life. PMID:23914012

  2. [Samuel Alexander Kinnier Wilson].

    PubMed

    Kikuchi, Raita

    2014-11-01

    Samuel Alexander Kinnier Wilson is considered a pioneer in extrapyramidal system research largely due to his dissertation on progressive lenticular degeneration, later known as "Wilson's Disease". His concept of neurological symptomatology was based on the clinical observations of Pierre Marie, Joseph Babinski and John Hughlings Jackson, who he observed when he was young. To keep focusing on the nature of actual symptoms while performing medical examinations is the essence of neurological symptomatology, which in turn form the spirit of neurology. This paper will discuss major events in Wilson's later life that would explain how his basic idea for neurological symptomatology was eventually formed. PMID:25407062

  3. Alexander Archipelago, Southeastern Alaska

    NASA Technical Reports Server (NTRS)

    2002-01-01

    West of British Columbia, Canada, and south of the Yukon Territory, the southeastern coastline of Alaska trails off into the islands of the Alexander Archipelago. The area is rugged and contains many long, U-shaped, glaciated valleys, many of which terminate at tidewater. The Alexander Archipelago is home to Glacier Bay National Park. The large bay that has two forks on its northern end is Glacier Bay itself. The eastern fork is Muir inlet, into which runs the Muir glacier, named for the famous Scottish-born naturalist John Muir. Glacier Bay opens up into the Icy Strait. The large, solid white area to the west is Brady Icefield, which terminates at the southern end in Brady's Glacier. To locate more interesting features from Glacier Bay National Park, take a look at the park service map. As recently as two hundred years ago, a massive ice field extended into Icy Strait and filled the Glacier Bay. Since that time, the area has experienced rapid deglaciation, with many large glaciers retreating 40, 60, even 80 km. While temperatures have increased in the region, it is still unclear whether the rapid recession is part of the natural cycle of tidewater glaciers or is an indicator of longer-term climate change. For more on Glacier Bay and climate change, read an online paper by Dr. Dorothy Hall, a MODIS Associate Science Team Member. Credit: Jacques Descloitres, MODIS Land Rapid Response Team, NASA/GSFC

  4. Alexander Lowen: An Energetic Man.

    ERIC Educational Resources Information Center

    Good, Glenn E.; Rabinowitz, Fredric E.

    1992-01-01

    Presents interview with Alexander Lowen, prominent psychotherapist, who discusses his personal and professional development, as well as the evolution of bioenergetic analysis. Includes a list of suggested readings by Lowen. (Author/NB)

  5. Neurocognitive decline in Alexander disease.

    PubMed

    Restrepo, June; Bernardin, Linda; Hammeke, Thomas

    2011-10-01

    Alexander disease is a neurological condition associated with prominent white matter deterioration. Its rarity and relatively rapid disease course have provided limited understanding into the cognitive effects of the illness. We report the serial neuropsychological findings of a 21-year-old with normal development and no medical history until age 9, when he experienced refractory sinusitis, stabbing headaches with vertigo, disorientation, and decline in academic and social settings. An MRI scan of the brain found acute demyelinating encephalomyelitis, with a preponderance of white matter degeneration in the bilateral frontal lobes. Interval MRIs showed continued degeneration. Confirmation of Alexander disease was made at age 20 through genetic testing. Four evaluations completed from ages 15 to 21 showed impairment across all cognitive domains. Cognitive deficits were most prominent in new learning and recent memory, executive functions, and fine motor dexterity, and less apparent in information processing and visual scanning speed. These results present evidence for a particular cognitive pattern in individuals with juvenile-onset Alexander disease. Despite extensive white matter degeneration in the frontal lobes, certain tasks associated with frontal lobe integrity were relatively preserved. Further research into the neuropsychological presentation of the subtypes of Alexander disease can enhance diagnostic clarity and treatment planning. PMID:21902566

  6. Conjecture of Alexander and Orbach.

    NASA Astrophysics Data System (ADS)

    Rudra, Jayanta; Doiron, Curtis

    2009-03-01

    The dynamical properties of fractal networks have received wide range of attention. Works on this area by several pioneering authors^1-2 have led to the introduction of the spectral dimension that dictates the dynamic properties on a fractal lattice. Most of the studies involving spectral dimension have been performed on a type of fractal lattice known as percolation network. Alexander and Orbach^2 conjectured that the spectral dimension might be exactly 4/3 for percolation networks with Euclidean dimension de >= 2. Recent numerical simulations, however, could not decisively prove or disprove this conjecture, although there are other indirect evidences that it is true. We apply a stochastic approach^3 to determine the spectral dimension of percolation network for de >= 2 and check the validity of the Alexander-Orbach conjecture. Our preliminary results on 2- and 3-dimensional percolation networks indeed show that Alexander-Orbach conjecture is true, resolving a long-standing debate. References: 1. P. G. deGennes, La Recherche 7 (1976) 919. 2. S. Alexander and R. Orbach, J. Phys. Lett. (Paris) 43 (1982) L625. 3. J. Rudra and J. Kozak, Phys. Lett A 151 (1990) 429.

  7. The Alexander Technique: An Acting Approach.

    ERIC Educational Resources Information Center

    Barker, Sarah A.

    2002-01-01

    Notes the discrepancy between students' use of the Alexander Technique in class and on stage. Discusses three fundamental self-use objectives of the Alexander Technique: the reduction of excess physical compression and muscularity; the unification of body/voice and thought; and the expansion of the field of attention. Demonstrates how each…

  8. Dancers' Application of the Alexander Technique

    ERIC Educational Resources Information Center

    Fortin, Sylvie; Girard, Fernande

    2005-01-01

    This qualitative study describes the experience of professional contemporary dancers studying and applying the Alexander Technique to their dancing. This study was motivated by: 1. years of teaching both dance and somatics, 2. a strong desire to better understand how the Alexander Technique can be applied by dancers, and 3. a gap that the…

  9. The Haunting Influence of Alexander Graham Bell

    ERIC Educational Resources Information Center

    Mitchell, Sue H.

    1971-01-01

    The article examines the significance that Alexander Graham Bell's attitude and actions had on the social and economic conditions experienced by deaf people during his lifetime and into the present. (CD)

  10. Cupola Corner 2 - Conversation With Alexander Samokutyaev

    NASA Video Gallery

    Astronaut Ron Garan speaks with fellow Expedition 28 flight engineer and Soyuz Commander Alexander Samokutyaev about using the view from the International Space Station to inspire people to make a ...

  11. A psychoanalytic study of Alexander the Great.

    PubMed

    Thomas, K R

    1995-12-01

    The purpose of this paper was to demonstrate how Freudian concepts such as the Oedipus complex, castration anxiety, fear of loss of love, the psychosexual stages of development, and the tripartite structure of personality can be used to understand the life and achievements of Alexander the Great. To accomplish this purpose, specific incidents, myths, and relationships in Alexander's life were analyzed from a Freudian psychoanalytic perspective. Green (1991), in his recent biography of Alexander, has questioned the merit of using Freudian concepts to understand Alexander's character. In fact, he stated specifically: If he (Alexander) had any kind of Oedipus complex it came in a poor second to the burning dynastic ambition which Olympias so sedulously fostered in him; those who insist on his psychological motivation would do better to take Adler as their mentor than Freud (p.56). Later, in the concluding section of his book, Green (1991, pp. 486-487) discounted Freudian interpretations of Alexander's distaste for sex, the rumors of his homosexual liaisons, his partiality for middle-aged or elderly ladies, and the systematic domination of his early years by Olympias as little more than the projected fears and desires of the interpreters. And again, an Adlerian power-complex paradigm was suggested as the preferable theoretical framework to use. Green's argument was based primarily on an exchange, reported originally by Plutarch, which took place between Alexander and Philip prior to Alexander's tutorship with Aristotle. Purportedly, Philip enjoined his son to study hard and pay close attention to all Aristotle said "so that you may not do a great many things of the sort that I am sorry I have done." At this point, Alexander "somewhat pertly" took Philip to task "because he was having children by other women besides his wife." Philip's reply was: "Well then, if you have many competitors for the kingdom, prove yourself honorable and good, so that you may obtain the

  12. The Mind-Body Connection: An Introduction to Alexander Technique.

    ERIC Educational Resources Information Center

    Madden, Cathy

    2003-01-01

    Explains that the Alexander Technique is a process that allows performers to improve physical-mental coordination while performing. Outlines the fundamentals of the Alexander Technique and how it can be applied for actors and drama teachers. Proposes that drama teachers can incorporate some of the Alexander Technique's fundamentals into their…

  13. Alexander Graham Bell: Teacher of the Deaf.

    ERIC Educational Resources Information Center

    Bruce, Robert V.

    The lecture on Alexander Graham Bell by Dr. Robert V. Bruce, the author of a biography of Bell, focuses on Bell's association with the Clarke School for the Deaf in Massachusetts. Noted are Bell's employment by the school at 25 years of age and the preceding period during which Bell taught elocution at a boys' school in Scotland and used his…

  14. The Remarkable Journey of Lloyd Alexander

    ERIC Educational Resources Information Center

    Tunnel, Michael O.; Jacobs, James S.

    2007-01-01

    This article features Lloyd Alexander, an author who has produced some of the most elegant and powerful prose in the history of modern children's literature. Lloyd began writing seriously in high school, and though he wrote and submitted many poems and short stories, his only success was being named a finalist in the "Writer's Digest" Short Story…

  15. 2. Historic American Buildings Survey J. Alexander, (for CFA) Photographer, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Historic American Buildings Survey J. Alexander, (for CFA) Photographer, 1971 DETAIL, MAIN ENTRANCE - Arthur C. Stanley House, 2370 Massachusetts Avenue Northwest, Washington, District of Columbia, DC

  16. 3. Historic American Buildings Survey J. Alexander, Photographer August 1968 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Historic American Buildings Survey J. Alexander, Photographer August 1968 DOUBLE PARLORS LOOKING WEST - Grafton Tyler Double House, 1314 Thirtieth Street Northwest, Washington, District of Columbia, DC

  17. 2. NORTH AND EAST ELEVATIONS, ALEXANDER'S MILL (WILSON'S MILL). THE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. NORTH AND EAST ELEVATIONS, ALEXANDER'S MILL (WILSON'S MILL). THE 2-1/1-STORY MAIN BLOCK, ERECTED IN 1855, HAS OVERTONES OF THE GREEK REVIVAL STYLE. Photographer: louise Taft Cawood, July 1986 - Alexander's Grist Mill, Lock 37 on Ohio & Erie Canal, South of Cleveland, Valley View, Cuyahoga County, OH

  18. 6. Historic American Buildings Survey Alexander Piaget, Photographer, April 9, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Historic American Buildings Survey Alexander Piaget, Photographer, April 9, 1934 DETAIL OF ROTUNDA - LOOKING NORTH - Old St. Louis Courthouse, Fourth to Broadway, Market to Chestnut Streets, Saint Louis, Independent City, MO

  19. 1. Historic American Buildings Survey Alexander Piaget, Photographer, April 9, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey Alexander Piaget, Photographer, April 9, 1934 GENERAL VIEW FROM NORTHEAST - Old St. Louis Courthouse, Fourth to Broadway, Market to Chestnut Streets, Saint Louis, Independent City, MO

  20. 7. Historic American Buildings Survey Alexander Piaget, Photographer, April 9, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Historic American Buildings Survey Alexander Piaget, Photographer, April 9, 1934 DETAIL OF ROTUNDA LOOKING NORTH - Old St. Louis Courthouse, Fourth to Broadway, Market to Chestnut Streets, Saint Louis, Independent City, MO

  1. 5. Historic American Buildings Survey Alexander Piaget, Photographer, April 9, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Historic American Buildings Survey Alexander Piaget, Photographer, April 9, 1934 Detail of Rotunda looking west. - Old St. Louis Courthouse, Fourth to Broadway, Market to Chestnut Streets, Saint Louis, Independent City, MO

  2. 2. Historic American Buildings Survey Alexander Piaget, Photographer, April 9, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Historic American Buildings Survey Alexander Piaget, Photographer, April 9, 1934 DETAIL OF EAST PORTICO - Old St. Louis Courthouse, Fourth to Broadway, Market to Chestnut Streets, Saint Louis, Independent City, MO

  3. 8. Historic American Buildings Survey Alexander Piaget, Photographer, April 9, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. Historic American Buildings Survey Alexander Piaget, Photographer, April 9, 1934 INTERIOR VIEW LOOKING UP INTO THE DOME - Old St. Louis Courthouse, Fourth to Broadway, Market to Chestnut Streets, Saint Louis, Independent City, MO

  4. 1. Historic American Buildings Survey J. Alexander, Photographer May 1968 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey J. Alexander, Photographer May 1968 EAST (FRONT) ELEVATION - Mount Zion United Methodist Church, 1334 Twenty-ninth Street Northwest, Washington, District of Columbia, DC

  5. 1. Historic American Buildings Survey J. Alexander, Photographer April 1969 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey J. Alexander, Photographer April 1969 3034 P STREET (right) AND ADJOINING ROWHOUSES, LOOKING EAST - Smith-Morton Row House, 3034 P Street Northwest, Washington, District of Columbia, DC

  6. Alexander von Humboldt and the Origins of Landscape Archaeology.

    ERIC Educational Resources Information Center

    Mathewson, Kent

    1986-01-01

    Reviews the life, theories, and influence of Alexander von Humboldt, the early nineteenth century founder of modern geography. Maintains that Humboldt's novel approaches to the study of landscape antiquities have value for contemporary students in cultural and historical geography. (JDH)

  7. 1. Historic American Buildings Survey Alexander Piaget, Photographer, April 10, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey Alexander Piaget, Photographer, April 10, 1934 VIEW FROM SOUTHEAST - Jean Baptiste Valle House, 99 South Main Street (Northwest corner of Main & Market Streets), Sainte Genevieve, Ste. Genevieve County, MO

  8. 2. Historic American Buildings Survey Alexander Piaget, Photographer, April 10, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Historic American Buildings Survey Alexander Piaget, Photographer, April 10, 1934 VIEW FROM SOUTHWEST - Jean Baptiste Valle House, 99 South Main Street (Northwest corner of Main & Market Streets), Sainte Genevieve, Ste. Genevieve County, MO

  9. 3. Historic American Buildings Survey Alexander Piaget, Photographer, April 10, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Historic American Buildings Survey Alexander Piaget, Photographer, April 10, 1934 VIEW FROM NORTH - Jean Baptiste Valle House, 99 South Main Street (Northwest corner of Main & Market Streets), Sainte Genevieve, Ste. Genevieve County, MO

  10. Astrocytic TDP-43 pathology in Alexander disease.

    PubMed

    Walker, Adam K; Daniels, Christine M LaPash; Goldman, James E; Trojanowski, John Q; Lee, Virginia M-Y; Messing, Albee

    2014-05-01

    Alexander disease (AxD) is a rare neurodegenerative disorder characterized pathologically by the presence of eosinophilic inclusions known as Rosenthal fibers (RFs) within astrocytes, and is caused by dominant mutations in the coding region of the gene encoding glial fibrillary acidic protein (GFAP). GFAP is the major astrocytic intermediate filament, and in AxD patient brain tissue GFAP is a major component of RFs. TAR DNA binding protein of 43 kDa (TDP-43) is the major pathological protein in almost all cases of the neurodegenerative disease amyotrophic lateral sclerosis (ALS) and ∼50% of frontotemporal lobar degeneration (FTLD), designated as FTLD-TDP. In ALS and FTLD-TDP, TDP-43 becomes insoluble, ubiquitinated, and pathologically phosphorylated and accumulates in cytoplasmic inclusions in both neurons and glia of affected brain and spinal cord regions. Previously, TDP-43 was detected in RFs of human pilocytic astrocytomas; however, involvement of TDP-43 in AxD has not been determined. Here we show that TDP-43 is present in RFs in AxD patient brains, and that insoluble phosphorylated full-length and high molecular weight TDP-43 accumulates in white matter of such brains. Phosphorylated TDP-43 also accumulates in the detergent-insoluble fraction from affected brain regions of Gfap(R236H/+) knock-in mice, which harbor a GFAP mutation homologous to one that causes AxD in humans, and TDP-43 colocalizes with astrocytic RF pathology in Gfap(R236H/+) mice and transgenic mice overexpressing human wild-type GFAP. These findings suggest common pathogenic mechanisms in ALS, FTLD, and AxD, and this is the first report of TDP-43 involvement in a neurological disorder primarily affecting astrocytes. PMID:24806671

  11. Obituary: Donald Alexander Macrae, 1916-2006

    NASA Astrophysics Data System (ADS)

    Seaquist, E. R.

    2007-12-01

    With the passing of Donald Alexander MacRae on 6 December 2006 at age 90, the astronomy community lost a visionary scientist and a great educator in the field. Don MacRae was born in Halifax, Nova Scotia, on 19 February 1916, to Donald Alexander and Laura Geddes (Barnstead) MacRae. His father was originally a classics scholar and preceptor of Greek and Latin at Princeton, but at the time of Don's birth in 1916 he was Dean of the Dalhousie Law School in Halifax. The family moved to Toronto, Ontario, in 1924 when his father joined the faculty of Osgoode Hall Law School in Toronto as a Professor of Law. After the family moved to Toronto, where he received most of his early education, he obtained his undergraduate degree in Mathematics and Physics in 1937 from the University of Toronto (U of T). He obtained the degree of A.M. in 1940 and of Ph.D. in 1943 from Harvard University under the mentorship of Bart Bok in the field of galactic structure. During his early career he worked briefly at the University of Pennsylvania, Cornell University, and Carbide and Chemical Corporation at Oak Ridge, Tennessee. For Don the latter work was a brief and somewhat uneasy association with the Manhattan Project. In 1946, he obtained a position at Case Institute of Technology (now Case Western Reserve University), where he worked until 1953. In 1953, he accepted a position at the U of T, replacing Ralph Williamson, who had earlier introduced Don to the emerging field of radio astronomy while they both were at Cornell. Don's primary research field was stellar spectroscopy, but his interests were much broader than this, and he possessed an abiding ability to interest students and faculty in new and emerging ideas. In the early 1960s he developed a strong interest in the nature and origin of the lunar surface, and discussed these extensively with colleagues. Many of his ideas on this subject were later confirmed by the lunar exploration program. Don's continuing interest in radio astronomy

  12. 8. View of southwest rear and southeast side of AlexanderAlmon ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. View of southwest rear and southeast side of Alexander-Almon House with cement block outbuilding to far left, facing north. - Alexander-Almon House, 130 Philip Almon Road, Roopville, Carroll County, GA

  13. Modeling Alexander disease with patient iPSCs reveals cellular and molecular pathology of astrocytes.

    PubMed

    Kondo, Takayuki; Funayama, Misato; Miyake, Michiyo; Tsukita, Kayoko; Era, Takumi; Osaka, Hitoshi; Ayaki, Takashi; Takahashi, Ryosuke; Inoue, Haruhisa

    2016-01-01

    Alexander disease is a fatal neurological illness characterized by white-matter degeneration and formation of Rosenthal fibers, which contain glial fibrillary acidic protein as astrocytic inclusion. Alexander disease is mainly caused by a gene mutation encoding glial fibrillary acidic protein, although the underlying pathomechanism remains unclear. We established induced pluripotent stem cells from Alexander disease patients, and differentiated induced pluripotent stem cells into astrocytes. Alexander disease patient astrocytes exhibited Rosenthal fiber-like structures, a key Alexander disease pathology, and increased inflammatory cytokine release compared to healthy control. These results suggested that Alexander disease astrocytes contribute to leukodystrophy and a variety of symptoms as an inflammatory source in the Alexander disease patient brain. Astrocytes, differentiated from induced pluripotent stem cells of Alexander disease, could be a cellular model for future translational medicine. PMID:27402089

  14. 12. Detail view of southeast side window of AlexanderAlmon House ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. Detail view of southeast side window of Alexander-Almon House with rain barrel at lower left and roof rafter tails at top, facing northwest. - Alexander-Almon House, 130 Philip Almon Road, Roopville, Carroll County, GA

  15. Obituary: Walter Alexander Feibelman, 1930-2004

    NASA Astrophysics Data System (ADS)

    Oergerle, William

    2005-12-01

    Walter Alexander Feibelman, 79, an astronomer who discovered the E-ring of Saturn, died of a heart attack 19 November 2004 at his home at Riderwood Village in Silver Spring, Maryland. Walter was born 30 October 1925 in Berlin, Germany to Bernard and Dora Feibelman. He came to the United States with his parents in 1941. They were some of the last German Jews to flee Nazi Germany. Years later, he reported his experiences in an account contributed to the U.S. Holocaust Memorial Museum. As a youth, he worked at a cleaning shop and as a soda jerk before taking a course in tool and die making. He worked at the Abbey Photo Corp. in New York and in a model-making firm, where he constructed models of aircraft for use in identification courses by the Army Air Forces. After high school, he attended the Carnegie Institute of Technology and received his BS degree in 1956. Until 1969, he was a research scientist at the University of Pittsburgh. While working as an assistant research professor in physics and astronomy at the University of Pittsburgh in 1967, he examined a photo of Saturn taken a year earlier at the university's Allegheny Observatory. The E-ring -- unlike the bright main rings, A, B, C, D and F -- is faint and not easily spotted. He paired his observation with calculations and announced his discovery, which remained unconfirmed until the Pioneer 11 flyby in 1979. Walter joined the Optical Astronomy Division of Goddard Space Flight Center in Greenbelt in 1969, and worked there until 2002, when he became an emeritus astronomer at NASA. He became associated with the International Ultraviolet Explorer project, and worked on developing detectors for the orbiting observatory's spectrograph. The project turned out to be one of NASA's most successful observatories, operating from 1978 to 1996. In his scientific career, he published more than 200 refereed articles, mainly on hot stars and planetary nebulae. He also wrote papers in the fields of photography, spectroscopy

  16. Obituary: Donald Alexander Macrae, 1916-2006

    NASA Astrophysics Data System (ADS)

    Seaquist, E. R.

    2007-12-01

    With the passing of Donald Alexander MacRae on 6 December 2006 at age 90, the astronomy community lost a visionary scientist and a great educator in the field. Don MacRae was born in Halifax, Nova Scotia, on 19 February 1916, to Donald Alexander and Laura Geddes (Barnstead) MacRae. His father was originally a classics scholar and preceptor of Greek and Latin at Princeton, but at the time of Don's birth in 1916 he was Dean of the Dalhousie Law School in Halifax. The family moved to Toronto, Ontario, in 1924 when his father joined the faculty of Osgoode Hall Law School in Toronto as a Professor of Law. After the family moved to Toronto, where he received most of his early education, he obtained his undergraduate degree in Mathematics and Physics in 1937 from the University of Toronto (U of T). He obtained the degree of A.M. in 1940 and of Ph.D. in 1943 from Harvard University under the mentorship of Bart Bok in the field of galactic structure. During his early career he worked briefly at the University of Pennsylvania, Cornell University, and Carbide and Chemical Corporation at Oak Ridge, Tennessee. For Don the latter work was a brief and somewhat uneasy association with the Manhattan Project. In 1946, he obtained a position at Case Institute of Technology (now Case Western Reserve University), where he worked until 1953. In 1953, he accepted a position at the U of T, replacing Ralph Williamson, who had earlier introduced Don to the emerging field of radio astronomy while they both were at Cornell. Don's primary research field was stellar spectroscopy, but his interests were much broader than this, and he possessed an abiding ability to interest students and faculty in new and emerging ideas. In the early 1960s he developed a strong interest in the nature and origin of the lunar surface, and discussed these extensively with colleagues. Many of his ideas on this subject were later confirmed by the lunar exploration program. Don's continuing interest in radio astronomy

  17. Alexander Falconer Sr Seamen's missionary in New Zealand, son Alexander Falconer medical superintendent for mentally ill, grandson Murray Falconer neurosurgeon.

    PubMed

    Hawgood, Barbara J

    2016-08-01

    Alexander Falconer Sr (1843-1915) came from Scotland to New Zealand. A practical Christian, he set up places of relaxation for miners, sailors and soldiers; he became the Seamen's Missionary. Son, Dr Alexander Falconer (1874-1955) trained at Otago University Medical School. As medical superintendent for the mentally ill, he urged the early introduction of psychotherapy. His son, Murray Falconer (1910-1977) was the first Nuffield Dominions Clinical Fellow, training in neurosurgery in Oxford. He was the first director of the Guy's-Maudsley Neurosurgical Unit in London and was internationally known for the surgical management of temporal lobe epilepsy in adults and children. PMID:26025843

  18. 46. Photocopy of photograph (Pentran file), (from Alexander Brown's Peninsula's ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    46. Photocopy of photograph (Pentran file), (from Alexander Brown's Peninsula's Last Street Cars, Daily Press, January 15, 1956) photographer unknown. The first streetcar (with dignitaries) to make the run from Newport News to a new housing development named Hilton Village in September 1918. - Newport News & Old Point Railway & Electric Company, Trolley Barn & Administration Building, 3400 Victoria Boulevard, Hampton, Hampton, VA

  19. The multivariable Alexander polynomial and modern knot theory

    SciTech Connect

    Saleur, H. . Dept. of Physics)

    1992-06-01

    This paper is a summary of several recent works (by the author and collaborators) that study the Conway-Alexander link invariant in the light of quantum groups and topological quantum field theories. Their purpose is to understand connections between modern knot theory and more classical topological concepts.

  20. All Aboard the Engine of Reform: Lamar Alexander.

    ERIC Educational Resources Information Center

    Harrington-Lueker, Donna

    1991-01-01

    Transformation of schools is the key to America 2000, an ambitious amalgam of ideas that Secretary of Education Lamar Alexander and his advisers have developed. The program's centerpiece is the creation of 535 "New American Schools" receiving a 1-time $1 million federal grant to develop exemplary programs. A sidebar describes the Department of…

  1. Alexander Meiklejohn in Search of Freedom and Dignity.

    ERIC Educational Resources Information Center

    Johnson, Tony W.

    1982-01-01

    Assesses the contributions of the philosopher/educator Alexander Meiklejohn. Discusses the influences of Jean-Jacques Rousseau, Immanuel Kant, and the U.S. Constitution on Meiklejohn's educational theories, which stressed that human freedom and dignity can be enhanced by rigorous examination of U.S. Supreme Court decisions and the meaning of…

  2. The Century-Old Wisdom of Alexander Graham Bell.

    ERIC Educational Resources Information Center

    Cornett, Orin

    1990-01-01

    This article reflects on Alexander Graham Bell's 1888 testimony before the Royal Commission of the United Kingdom on the Condition of the Deaf and Dumb, Etc. Excerpts are grouped by reference to (1) language education for the hearing impaired; (2) speechreading; (3) methods of teaching; (4) speech; and (5) sign language. (Author/PB)

  3. Teaching Nuclear Radiation and the Poisoning of Alexander Litvinenko

    ERIC Educational Resources Information Center

    David R. Lapp

    2008-01-01

    The recent international story about the death of the former KGB agent Alexander Litvinenko has more than just a few wondering about radiation poisoning and the sinister sounding polonium-210. I was preparing to begin a nuclear radiation unit the Monday after Thanksgiving 2006. As it turned out, Litvinenko died Thanksgiving Day after a short and…

  4. Alexander I. Ignatowski: a pioneer in the study of atherosclerosis.

    PubMed

    Konstantinov, Igor E; Jankovic, Gradimir M

    2013-01-01

    In 1908, Alexander I. Ignatowski (1875-1955) published his pioneering work that first revealed a relationship between cholesterol-rich food and experimental atherosclerosis. This early experimental work paved a way to the metabolic study of the mechanism of atherosclerosis. Herein, we present a brief account of Ignatowski's work and life. PMID:23914012

  5. Journalism and the Educational Views of Alexander Meiklejohn.

    ERIC Educational Resources Information Center

    Palmer, Mack R.

    Alexander Meiklejohn, who died in 1964 at the age of 92, was a constitutional scholar whose major interest was education. Among Meiklejohn's beliefs were the following: the social good should take precedence over individual achievement; the liberal arts college is the institution best suited to carry out an affirmative reading of the First…

  6. Alexander disease with mild dorsal brainstem atrophy and infantile spasms.

    PubMed

    Torisu, Hiroyuki; Yoshikawa, Yoko; Yamaguchi-Takada, Yui; Yano, Tamami; Sanefuji, Masafumi; Ishizaki, Yoshito; Sawaishi, Yukio; Hara, Toshiro

    2013-05-01

    We present the case of a Japanese male infant with Alexander disease who developed infantile spasms at 8 months of age. The patient had a cluster of partial seizures at 4 months of age. He presented with mild general hypotonia and developmental delay. Macrocephaly was not observed. Brain magnetic resonance imaging (MRI) findings fulfilled all MRI-based criteria for the diagnosis of Alexander disease and revealed mild atrophy of the dorsal pons and medulla oblongata with abnormal intensities. DNA analysis disclosed a novel heterozygous missense mutation (c.1154 C>T, p.S385F) in the glial fibrillary acidic protein gene. At 8 months of age, tonic spasms occurred, and electroencephalography (EEG) revealed hypsarrhythmia. Lamotrigine effectively controlled the infantile spasms and improved the abnormal EEG findings. Although most patients with infantile Alexander disease have epilepsy, infantile spasms are rare. This comorbid condition may be associated with the distribution of the brain lesions and the age at onset of Alexander disease. PMID:22818990

  7. View west of the James and Lucy Alexander gravestone and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View west of the James and Lucy Alexander gravestone and family plot among other demarcated family plots in the Female Union Band Cemetery. - Mount Zion Cemetery/ Female Union Band Cemetery, Bounded by 27th Street right-of-way N.W. (formerly Lyons Mill Road), Q Street N.W., & Mill Road N.W., Washington, District of Columbia, DC

  8. Alexander the Great and West Nile Virus Encephalitis

    PubMed Central

    Marr, John S.

    2003-01-01

    Alexander the Great died in Babylon in 323 BC. His death at age 32 followed a 2-week febrile illness. Speculated causes of death have included poisoning, assassination, and a number of infectious diseases. One incident, mentioned by Plutarch but not considered by previous investigators, may shed light on the cause of Alexander’s death. The incident, which occurred as he entered Babylon, involved a flock of ravens exhibiting unusual behavior and subsequently dying at his feet. The inexplicable behavior of ravens is reminiscent of avian illness and death weeks before the first human cases of West Nile virus infection were identified in the United States. We posit that Alexander may have died of West Nile encephalitis. PMID:14725285

  9. Nitric oxide mediates glial-induced neurodegeneration in Alexander disease

    PubMed Central

    Wang, Liqun; Hagemann, Tracy L.; Kalwa, Hermann; Michel, Thomas; Messing, Albee; Feany, Mel B.

    2015-01-01

    Glia play critical roles in maintaining the structure and function of the nervous system; however, the specific contribution that astroglia make to neurodegeneration in human disease states remains largely undefined. Here we use Alexander disease, a serious degenerative neurological disorder caused by astrocyte dysfunction, to identify glial-derived NO as a signalling molecule triggering astrocyte-mediated neuronal degeneration. We further find that NO acts through cGMP signalling in neurons to promote cell death. Glial cells themselves also degenerate, via the DNA damage response and p53. Our findings thus define a specific mechanism for glial-induced non-cell autonomous neuronal cell death, and identify a potential therapeutic target for reducing cellular toxicity in Alexander disease, and possibly other neurodegenerative disorders with glial dysfunction. PMID:26608817

  10. Nitric oxide mediates glial-induced neurodegeneration in Alexander disease.

    PubMed

    Wang, Liqun; Hagemann, Tracy L; Kalwa, Hermann; Michel, Thomas; Messing, Albee; Feany, Mel B

    2015-01-01

    Glia play critical roles in maintaining the structure and function of the nervous system; however, the specific contribution that astroglia make to neurodegeneration in human disease states remains largely undefined. Here we use Alexander disease, a serious degenerative neurological disorder caused by astrocyte dysfunction, to identify glial-derived NO as a signalling molecule triggering astrocyte-mediated neuronal degeneration. We further find that NO acts through cGMP signalling in neurons to promote cell death. Glial cells themselves also degenerate, via the DNA damage response and p53. Our findings thus define a specific mechanism for glial-induced non-cell autonomous neuronal cell death, and identify a potential therapeutic target for reducing cellular toxicity in Alexander disease, and possibly other neurodegenerative disorders with glial dysfunction. PMID:26608817

  11. Dr Alexander Graham Bell--audiologist and speech therapist.

    PubMed

    Chakravorty, R C

    1976-09-01

    Alexander Graham Bell is best known for his role in the invention of the telephone. However, he had a lifelong involvement in speech therapy and audiology besides many other medical investigations. He was also awarded an honorary MD degree from Heidelberg University. In this, the 100th anniversary of his invention of the telephone, his life and some of his medical interests are briefly reviewed. PMID:786234

  12. Confirmation of Cosmological Bounces Predicted by Alexander Friedmann

    NASA Astrophysics Data System (ADS)

    Nurgaliev, Ildus

    2011-06-01

    It is shown that taking into consideration vorticity-related component of cosmological motion averts singularity and explains acceleration of the expansion. No mystic matter with dark energy is needed. That energy belongs to the local rotational motion (vorticity). Einstein's idea on static universe occurs to be encompassing conception for the standard cosmology, as well as for the emerging new (oscillating) one. Alexander Friedman gave to us its verbal model and was the most well prepared to give mathematical one.

  13. Alexander technique and Feldenkrais method: a critical overview.

    PubMed

    Jain, Sanjiv; Janssen, Kristy; DeCelle, Sharon

    2004-11-01

    This article develops an overall better understanding of the Alexander technique and Feldenkrais method. Initially, a brief history is provided to lay the groundwork for the development of these techniques. A description of the techniques, training requirements, and mechanism of action follows. Indications, contraindications, and patient selection are discussed. This article reviews and identifies what research has been completed and what areas need further investigation. Overall, the goal is to establish a guide to aid in determining who may benefit from these techniques and outcomes to expect when using these techniques. PMID:15458754

  14. [Alexander Borodin--physician, chemist, scientist, teacher and composer].

    PubMed

    Vik, T

    1998-12-10

    Concert programmes and CD covers suggest that the Russian composer Alexander Borodin (1833-87) was also a great scientist. In this article we examine this proposition. Borodin was born in St. Petersburg as the illegitimate son of a Russian nobleman. As a boy his talents ranged from music to chemistry and languages. Borodin studied medicine at the Medico-Surgical Academy in St. Petersburg from 1850 to 1855 and defended his doctoral thesis on the similarity between arsenic and phosphoric acid in 1858. He did not, however, feel comfortable in his role as a doctor, and soon started to work as a chemist. In 1864 he was appointed professor of chemistry at the Medico-Surgical Academy. In 1861, Borodin attended the first international congress of chemistry in Karlsruhe, and he was among the founders of the Russian Chemical Society in 1868. He published 42 articles and was a friend of Dmitri Mendeleev, the scientist who described the periodic system. In 1872, Borodin started the first medical courses for women in Russia. It seems warranted to conclude that Alexander Borodin was indeed a great scientist and university teacher, though his immortality was earned by his leisure time activities. PMID:9914755

  15. Alexander disease - astrogliopathy considered as leukodystrophy - experience of an institution.

    PubMed

    Mierzewska, Hanna; Mierzewska-Schmidt, Magdalena; Salomons, Gajja S; Dudzińska, Magdalena; Szczepanik, Elżbieta

    2016-01-01

    Alexander Disease (ALXDRD) is an autosomal dominant leukodystrophy caused by mutation in one allele of GFAP gene, encoding glial fibrillary acidic protein (GFAP). Most cases occur due to de novo. There are three clinical subtypes of ALXDRD: infantile, juvenile and adult form, but congenital form is also outlined. The disease's spectrum comprises of macrocephaly, progressive pyramidal signs, and seizures in congenital and infantile subtypes. Neuropathologically are enormous number of Rosenthal fibers (RF) mainly around vessels, in subependymal and subpial regions are found. The diagnosis is based on the typical findings on MRI: diffuse white mater lesions with frontal regions preponderance and possibly on the detection of the gene mutation. Here we present six Polish children affected of Alexander disease with congenital (1), infantile (4) and juvenile (1) form. Five of them were previously misdiagnosed as cerebral palsy or unspecific developmental delay; two patients had MRI because of another suspicion, before specific diagnosis was established. Molecular analysis performed in four cases confirmed mutations of GFAP gene; all mutation were de novo. The role of astroglia in brain is shortly reviewed. PMID:27442695

  16. 33 CFR 162.250 - Port Alexander, Alaska; speed of vessels.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Port Alexander, Alaska; speed of... Alexander, Alaska; speed of vessels. (a) Definition. The term “Port Alexander” includes the entire inlet from its head to its entrance from Chatham Strait. (b) Speed. The speed of all vessels of 5 tons...

  17. 33 CFR 162.250 - Port Alexander, Alaska; speed of vessels.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Port Alexander, Alaska; speed of... Alexander, Alaska; speed of vessels. (a) Definition. The term “Port Alexander” includes the entire inlet from its head to its entrance from Chatham Strait. (b) Speed. The speed of all vessels of 5 tons...

  18. 33 CFR 162.250 - Port Alexander, Alaska; speed of vessels.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Port Alexander, Alaska; speed of... Alexander, Alaska; speed of vessels. (a) Definition. The term “Port Alexander” includes the entire inlet from its head to its entrance from Chatham Strait. (b) Speed. The speed of all vessels of 5 tons...

  19. 76 FR 28226 - Ndahendekire Barbara v. African Shipping; Njoroge Muhia; Alco Logistics, Llc; Brenda Alexander...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-16

    ... Ndahendekire Barbara v. African Shipping; Njoroge Muhia; Alco Logistics, Llc; Brenda Alexander; and AIR 7 Seas... ``Complainant,'' against African Shipping; Njoroge Muhia, ALCO Logistics, LLC; Brenda Alexander; and Air 7 Seas Transport Logistics, Inc.; hereinafter ``Respondents''. Complainant asserts that she is acting agent...

  20. Kinesthetic Ventures Informed by the Work of F. M. Alexander, Stanislavski, Peirce, and Freud.

    ERIC Educational Resources Information Center

    Bouchard, Ed; Wright, Ben; Protzel, Michael, Ed.

    This book is about education harvested from self-observation. F. Matthias Alexander (1869-1955) studied the experience of self formation, working with motor habits. His method is used in performing arts training to enhance bodily and vocal expression. Like Alexander, Konstantine Stanislavski (1863-1938) and Sigmund Freud (1856-1939) studied human…

  1. 33 CFR 162.250 - Port Alexander, Alaska; speed of vessels.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Port Alexander, Alaska; speed of... Alexander, Alaska; speed of vessels. (a) Definition. The term “Port Alexander” includes the entire inlet from its head to its entrance from Chatham Strait. (b) Speed. The speed of all vessels of 5 tons...

  2. 33 CFR 162.250 - Port Alexander, Alaska; speed of vessels.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Port Alexander, Alaska; speed of... Alexander, Alaska; speed of vessels. (a) Definition. The term “Port Alexander” includes the entire inlet from its head to its entrance from Chatham Strait. (b) Speed. The speed of all vessels of 5 tons...

  3. Teaching Nuclear Radiation and the Poisoning of Alexander Litvinenko

    NASA Astrophysics Data System (ADS)

    Lapp, David R.

    2008-03-01

    The recent international story about the death of the former KGB agent Alexander Litvinenko has more than just a few wondering about radiation poisoning and the sinister sounding polonium-210. I was preparing to begin a nuclear radiation unit the Monday after Thanksgiving 2006. As it turned out, Litvinenko died Thanksgiving Day after a short and terrible three-week illness. Having the story continue to unfold throughout the next two weeks of the new unit provided a daily opportunity for students to see the relevance of what we were doing in class. My students were able to have meaningful and informed conversations with their peers and parents over an important international event. They even began to feel a bit like authorities themselves when listening to experts respond to media questions about polonium-210 and nuclear radiation in general. This paper discusses some of the ways that the story of Litvinenko was used while presenting the topic of nuclear radiation.

  4. The Astronomer Alexander I. Postoiev (1900-1976)

    NASA Astrophysics Data System (ADS)

    Dos Santos, P. M.; Matsuura, O. T.

    This is a biographical note on the life of Dr Alexander I. Postoiev, a victim of Stalin's purge of Soviet astronomers in 1936-1937 (McCutcheon, 1985). Along with his family, he left the Soviet Union in 1943, and lived in Germany as a refugee and "displaced person" until 1952, when he moved to Brazil. Then he started the second part of his professional career. Thanks to his efforts the Astronomical and Geophysical Institute (IAG) from the University of Sao Paulo (USP) was involved, for the first time, in programme of international cooperation, thus contributing to the institutional consolidation of IAG/USP as a leading centre of astronomical research and teaching today in Brazil.

  5. Alexander the Great's tombolos at Tyre and Alexandria, eastern Mediterranean

    NASA Astrophysics Data System (ADS)

    Marriner, N.; Goiran, J. P.; Morhange, C.

    2008-08-01

    Tyre and Alexandria's coastlines are today characterised by wave-dominated tombolos, peculiar sand isthmuses that link former islands to the adjacent continent. Paradoxically, despite a long history of inquiry into spit and barrier formation, understanding of the dynamics and sedimentary history of tombolos over the Holocene timescale is poor. At Tyre and Alexandria we demonstrate that these rare coastal features are the heritage of a long history of natural morphodynamic forcing and human impacts. In 332 BC, following a protracted seven-month siege of the city, Alexander the Great's engineers cleverly exploited a shallow sublittoral sand bank to seize the island fortress; Tyre's causeway served as a prototype for Alexandria's Heptastadium built a few months later. We report stratigraphic and geomorphological data from the two sand spits, proposing a chronostratigraphic model of tombolo evolution.

  6. Alexander Thomas Augusta--physician, teacher and human rights activist.

    PubMed

    Butts, Heather M

    2005-01-01

    Commissioned surgeon of colored volunteers, April 4, 1863, with the rank of Major. Commissioned regimental surgeon on the 7th Regiment of U.S. Colored Troops, October 2, 1863. Brevet Lieutenant Colonel of Volunteers, March 13, 1865, for faithful and meritorious services--mustered out October 13, 1866. So reads the tombstone at Arlington National Cemetery of Alexander Thomas Augusta, the first black surgeon commissioned in the Union Army during the Civil War and the first black officer-rank soldier to be buried at Arlington Cemetery. He was also instrumental in founding the institutions that later became the hospital and medical college of Howard University and the National Medical Association. PMID:15719881

  7. Alexander von Humboldt's perceptions of colonial Spanish America.

    PubMed

    Rebok, Sandra

    2009-01-01

    This study presents an in-depth analysis of Alexander von Humboldt's descriptions and critical comments on the colonial society of the different regions he visited during his well-known expedition through the Americas (1799-1804). The criticisms of colonialism that he expressed, reflecting his personal convictions, have already been the focal point of many studies, but Humboldt also was able to offer a more differentiated assessment through comparisons of regional and local traditions and developments. This essay focuses on his personal diaries, which offer many interesting comments on colonial societies. These considerations and impressions made during the expedition are of particular scholarly value since they were not subject to censorship of any kind. PMID:19852391

  8. Effects of Alexander Technique training experience on gait behavior in older adults.

    PubMed

    O'Neill, Matthew M; Anderson, David I; Allen, Diane D; Ross, Christopher; Hamel, Kate A

    2015-07-01

    Heightened fall risk, potentially caused by aging-related changes in gait, is a serious health issue faced by older adults. The Alexander Technique is thought to improve balance and motor function; however, the technique's effect on gait has not been studied. The purpose of this study was to examine the effect of Alexander Technique training in older adults on the temporospatial characteristics of gait and medio-lateral center of mass displacement during fast and comfortably paced over-ground walking. Six licensed Alexander Technique teachers and seven controls between the ages of 60 and 75 years of age participated in the study. Alexander Technique teachers exhibited a reduction in medio-lateral center of mass displacement during fast paced walking compared to comfortably paced walking that was not present in controls. Due to this difference Alexander Technique teachers displayed a smaller medio-lateral Center of Mass displacement compared to controls during fast paced walking. Alexander Technique teachers also demonstrated significantly smaller stride width and lower gait timing variability compared to controls. These findings, which suggest superior control of dynamic stability during gait and potentially reduced fall risk in Alexander Technique teachers, warrant further study. PMID:26118520

  9. Alexander Disease: A Novel Mutation in GFAP Leading to Epilepsia Partialis Continua.

    PubMed

    Bonthius, Daniel J; Karacay, Bahri

    2016-06-01

    Alexander disease is a genetically induced leukodystrophy, due to dominant mutations in the glial fibrillary acidic protein (GFAP ) gene, causing dysfunction of astrocytes. We have identified a novel GFAP mutation, associated with a novel phenotype for Alexander disease. A boy with global developmental delay and hypertonia was found to have a leukodystrophy. Genetic analysis revealed a heterozygous point mutation in exon 6 of the GFAP gene. The guanine-to-adenine change causes substitution of the normal glutamic acid codon (GAG) with a mutant lysine codon (AAG) at position 312 (E312 K mutation). At the age of 4 years, the child developed epilepsia partialis continua, consisting of unabating motor seizures involving the unilateral perioral muscles. Epilepsia partialis continua has not previously been reported in association with Alexander disease. Whether and how the E312 K mutation produces pathologic changes and clinical signs that are unique from other Alexander disease-inducing mutations in GFAP remain to be determined. PMID:26719496

  10. The effect of Alexander technique training program: A qualitative study of ordinary behavior application.

    PubMed

    Kim, Soo-Yeon; Baek, Soon Gi

    2014-12-01

    The purpose of this study was to configure and apply the Alexander technique training program and assess the effect of program through physical, emotional and behavioral aspects. To achieve the research aims, qualitative research method had been conducted, subjecting 8 people, who were participating in Alexander Technique training program for this study. The study used focus group interview method for collecting date and employed for the interview method by mixing the semi-structured and unstructured questionnaire. The results were followings. First, one could develop body awareness and body consciousness through experiencing lived bodily sensation. Second, from Alexander Technique training program, people experienced psycho & physical's equilibrium. Third, one could change not only the manner of use of body but also the attitude to the life from conscious attention to daily ordinary movement. The results provided empirical evidence of Alexander Technique training program's functions in terms of physical, emotional and behavioral aspect through the process of consciousness control from lived body education. PMID:25610819

  11. IN MEMORIAM: In Memoriam: Alexander A Golovin and Alexei M Oparin In Memoriam: Alexander A Golovin and Alexei M Oparin

    NASA Astrophysics Data System (ADS)

    2008-10-01

    In Memoriam of Alexander A Golovin (1962-2008) Alexander (Sasha) Golovin passed away on 10 September 2008. Sasha's scientific heritage includes seminal works in different fields of physics, from Marangoni convection to self-assembly of quantum dots, and from combustion fronts to anomalous diffusion in flows and on a crystal surface. A graduate of the Moscow Institute for Physics and Technology, he had very broad scientific interests and a unique ability to identify and solve new, intellectually challenging and technologically important problems. One of the basic fields of Sasha's research was the fluid dynamics in systems with interfaces. His favorite subject was the motion of droplets, bubbles and particles in the presence of heat and mass transfer. Sasha's early works contained the discovery of the spontaneous motion of droplets due to the Marangoni effect and the investigation of the interaction between solid particles, bubbles and droplets caused by the Marangoni effect, which is a crucial factor that determines the effect of heat/mass transfer on the rate of coalescence. In both cases, Sasha's work was the first in a long sequence of papers written by different authors. Later, Sasha returned to that field when studying such fascinating subjects as levitation of droplets above the surface of an evaporating liquid and encapsulation of particles and bubbles by an advancing solidification front. The subject of interfacial hydrodynamics overlaps with another basic field of Sasha's research, the theory of pattern formation. The contribution of Sasha's work to the modern understanding of the variety of pattern formation phenomena is significant. It includes the analysis of the interaction between long-wave and short-wave instability modes in Marangoni convection, investigation of the large-scale Marangoni convection that led to the prediction of different patterns including quasipatterns, and the description of various non-potential effects in Marangoni convection

  12. Alexander Forbes, Walter Cannon, and science-based literature.

    PubMed

    Garson, Justin

    2013-01-01

    The Harvard physiologists Alexander Forbes (1882-1965) and Walter Bradford Cannon (1871-1945) had an enormous impact on the physiology and neuroscience of the twentieth century. In addition to their voluminous scientific output, they also used literature to reflect on the nature of science itself and its social significance. Forbes wrote a novel, The Radio Gunner, a literary memoir, Quest for a Northern Air Route, and several short stories. Cannon, in addition to several books of popular science, wrote a literary memoir in the last year of his life, The Way of an Investigator. The following will provide a brief overview of the life and work of Forbes and Cannon. It will then discuss the way that Forbes used literature to express his views about the changing role of communications technology in the military, and his evolving view of the nervous system itself as a kind of information-processing device. It will go on to discuss the way that Cannon used literature to articulate the horrors he witnessed on the battlefield, as well as to contribute to the philosophy of science, and in particular, to the logic of scientific discovery. Finally, it will consider the historical and philosophical value of deeper investigation of the literary productions of scientists. PMID:24290268

  13. Expedition 8 Crew Interviews: Alexander Y. Kaleri - FE

    NASA Technical Reports Server (NTRS)

    2003-01-01

    Russian cosmonaut Alexander Y. Kaleri, Flight Engineer on Expedition 8 to the International Space Station (ISS), answers interview questions on this video, either himself or with the help of an interpreter. The questions cover: 1) The goal of the expedition; 2) The place in history of Mir; 3) The reaction to the loss of Columbia in Houston; 4) Why the rewards of spaceflight are worth the risks; 5) Why he decided to become a cosmonaut; 6) His memory of Yuri Gagarin's first flight; 7) What happens on a Soyuz capsule during launch and flight; 8) Are Soyuz maneuvers automatic or manual; 8) How the ISS science mission will be advanced during his stay; 9) The responsibilities of a Flight Engineer onboard the ISS; 10) Extravehicular activity (EVA) plans at that time; 11) The Shuttle Return to Flight and his preference for a Shuttle or Soyuz landing; 12) Why the last Soyuz landing was too rough; 13) The most valueable contribution of the ISS program.

  14. What is the alternative to the Alexander-Orbach relation?

    NASA Astrophysics Data System (ADS)

    Sokolov, Igor M.

    2016-03-01

    The Alexander-Orbach (AO) relation d w = 2d f /d s connecting the fractal dimension of a random walk’s (RW) trajectory d w or the exponent of anomalous diffusion α = 2/d w on a fractal structure with the fractal and spectral dimension of the structure itself plays a key role in discussion of dynamical properties of complex systems including living cells and single biomolecules. This relation however does not hold universally and breaks down for some structures like diffusion limited aggregates and Eden trees. We show that the alternative to the AO relation is the explicit dependence of the coefficient of the anomalous diffusion on the system’s size, i.e. the absence of its thermodynamical limit. The prerequisite for its breakdown is the dependence of the local structure of possible steps of the RW on the system’s size. The discussion is illustrated by the examples of diffusion on a Koch curve (AO-conform) and on a Cantor dust (violating AO relation).

  15. Astrocyte pathology in Alexander disease causes a marked inflammatory environment.

    PubMed

    Olabarria, Markel; Putilina, Maria; Riemer, Ellen C; Goldman, James E

    2015-10-01

    Astrocytes and microglia are commonly involved in a wide variety of CNS pathologies. However, they are typically involved in a secondary response in which many cell types are affected simultaneously and therefore it is difficult to know their contributions to the pathology. Here, we show that pathological astrocytes in a mouse model of Alexander disease (AxD; GFAP (Tg);Gfap (+/R236H)) cause a pronounced immune response. We have studied the inflammatory response in the hippocampus and spinal cord of these mice and have found marked microglial activation, which follows that of astrocytes in a spatial pathological progression, as shown by increased levels of Iba1 and microglial cell (Iba1+) density. RNA sequencing and subsequent gene ontology (GO) analysis revealed that a majority of the most upregulated genes in GFAP (Tg);Gfap (+/R236H) mice are directly associated with immune function and that cytokine and chemokine GO attributes represent nearly a third of the total immune attributes. Cytokine and chemokine analysis showed CXCL10 and CCL2 to be the most and earliest increased molecules, showing concentrations as high as EAE or stroke models. CXCL10 was localized exclusively to astrocytes while CCL2 was also present in microglia. Despite the high levels of CXCL10 and CCL2, T cell infiltration was mild and no B cells were found. Thus, mutations in GFAP are sufficient to trigger a profound inflammatory response. The cellular stress caused by the accumulation of GFAP likely leads to the production of inflammatory molecules and microglial activation. Examination of human AxD CNS tissues also revealed microglial activation and T cell infiltrates. Therefore, the inflammatory environment may play an important role in producing the neuronal dysfunction and seizures of AxD. PMID:26296699

  16. Cyclicity in Silurian island-arc carbonates, Alexander terrane, Alaska

    SciTech Connect

    Kittredge, L.E.; Soja, C.M. . Dept. of Geology)

    1993-03-01

    Silurian carbonates from Alaska (Alexander terrane) record the evolution of a submarine platform during waning volcanism in an island arc. A detailed stratigraphic analysis of a 47 meter-thick sequence revealed the existence of cyclically repeated limestones: coral-stromatoporoid wackestones alternate with oncoid packstones and bioturbated, silty lime mudstones. The coral-stromatoporoid deposits are characterized by a low-diversity assemblage of dendroid corals, massive stromatoporoids, Atrypoidea brachiopods, and rare occurrences of biostromes associated with Solenopora, high-spired gastropods, and crinoids. Oncoids typically are 2-6 mm in diameter and form massive, meter-thick units. Coated grains are symmetrically developed, have a shell or algal nucleus, and are also a minor component of coral-stromatoporoid beds. These lithologic units form seven, shallowing-upwards cycles (parasequences) that range in thickness from 3-9 meters. Coral-stomatoporoid wackestones form the base of each cycle and grade upwards into oncoid packstones with silty, lime mudstones at the top. This succession of lithofacies within each cycle reflects an increase in energy levels from relatively deeper water environments to relatively shallower ones. The lack of abrasion in the corals and stromatoporoids suggests predominantly quiet-water conditions in shallow subtidal areas affected by periodic turbulence. Comparison with correlative sections in Alaska and lack of correspondence with global sea level curves suggest that the primary cause of cyclicity was tectonic perturbations with secondary eustatic effects. Cyclic deposition in peri/subtidal sites was terminated by rapid drowning of the carbonate platform during late Silurian orogenesis.

  17. The life and death of Alexander Bogdanov, physician.

    PubMed

    Huestis, D W

    1996-08-01

    It was early in April in 1928 when the word went out in Moscow that Alexander Bogdanov had died. He was a controversial figure, an old Bolshevik who had left that party long before the 1917 revolution and never returned. All the same, he had had Lenin's respect as a scientist (as long as he stayed out of politics). More recently, he also had the support of the new party strong man, Stalin. Bogdanov opposed the growing despotism of the "dictatorship of the proletariat", under which slogan Communist autocracy was being developed. But he was respected as a tireless propagandist for the socialist cause, an enthusiastic teacher of the proletariat, and a writer of arcane science and philosophy. Bogdanov was held in such respect that Communist bigwigs spoke glowingly at the funeral, praising his intellect, courage, and dedication to science and humanity. They did not fail to point out that he had split with his one-time friend, Lenin, and had succumbed to ideological "errors". Indeed, he had powerful enemies in the early Soviet state. Bogdanov was a physician, economist, philosopher, natural scientist, writer of utopian science fiction, poet, teacher, politician (unsuccesful), lifelong revolutionary, forerunner of what we now call cybernetics and organizational science, and founder of the world's first institution devoted entirely to the field of blood transfusion. You could call him a Renaissance man. Although he clearly fitted the category of the late-nineteenth-century Russian intellectual revolutionary, Bogdanov differed from most of them in being no dilettante. More than just a theorist, he was an active scientist and physician. As a teacher, he firmly believed that education and indoctrination could alter people's ways of thinking and behaving, and that humanity could be perfected under socialism. Like many revolutionaries, Bogdanov tried to keep ahead of the Tsar's police by using a variety of pseudonyms, among them Riadavoy, Werner, Maximov, and Bogdanov. After

  18. Obituary: Alexander (Andy) Franz Lubenow, 1956-2005

    NASA Astrophysics Data System (ADS)

    Buie, Marc William

    2006-12-01

    Alexander (Andy) Franz Lubenow, Program Coordinator at the Space Telescope Science Institute, was diagnosed with cancer of the gallbladder, pancreas, and liver in May 2005 and died on 29 September 2005. He was forty-nine. Andy was born to Bodo and Helen Lubenow in St. Paul, Minnesota on 4 January 1956. In 1964 at the age of eight, he moved with his family to Buenos Aires, Argentina, and attended the American Community School there until returning with his family in 1973 to St. Paul. Argentina had a big impact on Andy's future as an astronomer. He later recalled how he had observed and was puzzled by the "upside-down" appearance of the Moon in the southern hemisphere. In Argentina, he built his first telescope using a mirror he had ground himself. He never parted ways with that instrument. Andy did not follow a standard educational track. He spent two years at St. Olaf College in Northfield, Minnesota, before transferring to the University of Minnesota, where he earned his bachelor's degree and began work towards a master's degree in astrophysics. Later he transferred to the University of Illinois at Urbana-Champaign, where he remained until Dr. Peter Stockman hired him to work on the Hubble Space Telescope project. While in school, he worked as a teacher's assistant, taught night school, and gave demonstrations of stargazing. He was an excellent teacher and had a flair for writing. He later wrote articles for a sailing magazine and a pilot's magazine. Andy was a very practical, meticulous, and steady worker, attributes that he combined with an understated and dry sense of humor. He was always able to find a way through a problem, no matter how sticky. If a job required him to roll up his sleeves and get it done through hard work, he would persevere. Nevertheless, he was always on the lookout for an easier way. He had no patience for being forced to deal with stupid things for stupid reasons. At work at the Space Telescope Science Institute (STScI), Andy was

  19. Alexander von Humboldt's charts of the Earth's magnetic field: an assessment based on modern models

    NASA Astrophysics Data System (ADS)

    Mandea, M.; Korte, M.; Soloviev, A.; Gvishiani, A.

    2010-11-01

    The 19th century witnessed a resurgence of interest in Earth's magnetic field. Both observational and theoretical aspects were involved, and one of the emblematic figures of this period was Alexander von Humboldt. Throughout a long life he maintained a strong interest in a broad area of subjects, however, here we are interested in his role in geomagnetism, and particularly in his pioneering contributions to charting the geomagnetic field. Alexander von Humboldt efforts in measuring and charting the Earth's magnetic field are recounted and the maps of declination, inclination and total intensity he had prepared are compared, favorably, with maps for the same epoch based on a modern model of the geomagnetic field, gufm1. This modern assessment of the accuracy of von Humboldt's geomagnetic charts illustrates the importance of his work, being also our homage to the 150th anniversary of the death of Alexander von Humboldt.

  20. Identification of metapopulation dynamics among Northern Goshawks of the Alexander Archipelago, Alaska, and Coastal British Columbia

    USGS Publications Warehouse

    Sonsthagen, Sarah A.; McClaren, Erica L.; Doyle, Frank I.; Titus, K.; Sage, George K.; Wilson, Robert E.; Gust, J.R.; Talbot, Sandra L.

    2012-01-01

    Northern Goshawks occupying the Alexander Archipelago, Alaska, and coastal British Columbia nest primarily in old-growth and mature forest, which results in spatial heterogeneity in the distribution of individuals across the landscape. We used microsatellite and mitochondrial data to infer genetic structure, gene flow, and fluctuations in population demography through evolutionary time. Patterns in the genetic signatures were used to assess predictions associated with the three population models: panmixia, metapopulation, and isolated populations. Population genetic structure was observed along with asymmetry in gene flow estimates that changed directionality at different temporal scales, consistent with metapopulation model predictions. Therefore, Northern Goshawk assemblages located in the Alexander Archipelago and coastal British Columbia interact through a metapopulation framework, though they may not fit the classic model of a metapopulation. Long-term population sources (coastal mainland British Columbia) and sinks (Revillagigedo and Vancouver islands) were identified. However, there was no trend through evolutionary time in the directionality of dispersal among the remaining assemblages, suggestive of a rescue-effect dynamic. Admiralty, Douglas, and Chichagof island complex appears to be an evolutionarily recent source population in the Alexander Archipelago. In addition, Kupreanof island complex and Kispiox Forest District populations have high dispersal rates to populations in close geographic proximity and potentially serve as local source populations. Metapopulation dynamics occurring in the Alexander Archipelago and coastal British Columbia by Northern Goshawks highlight the importance of both occupied and unoccupied habitats to long-term population persistence of goshawks in this region.

  1. Another View of Dynamic Criteria: A Critical Reanalysis of Barrett, Caldwell, and Alexander.

    ERIC Educational Resources Information Center

    Austin, James T.; And Others

    1989-01-01

    A critical reanalysis of Barrett, Caldwell, and Alexander's (1985) critique of dynamic criteria. Summarizes and questions Barrett, et al.'s three definitions of dynamic criteria and their conclusion that reported temporal changes in criteria could be explained by methodological artifacts. A greater focus on dynamic criteria as constructs is…

  2. Rejoinder to Austin, Humphreys, and Hulin: Critical Reanalysis of Barrett, Caldwell and Alexander.

    ERIC Educational Resources Information Center

    Barrett, Gerald V.; Alexander, Ralph A.

    1989-01-01

    Responds to Austin, Humphreys, and Hulin's (1989) critique of Barrett, Caldwell, and Alexander, suggesting that the burden of proof still rests on the advocates of the concept of dynamic criteria, and that empirical support is lacking for the existence of dynamic criteria as a simplex. Contrary evidence from educational, organizations, and…

  3. Holocene morphogenesis of Alexander the Great's isthmus at Tyre in Lebanon

    PubMed Central

    Marriner, Nick; Morhange, Christophe; Meulé, Samuel

    2007-01-01

    In 332 B.C., Alexander the Great constructed an ≈1,000-m-long causeway to seize the offshore island of Tyre. The logistics behind this engineering feat have long troubled archaeologists. Using the Holocene sedimentary record, we demonstrate that Alexander's engineers cleverly exploited a shallow proto-tombolo, or sublittoral sand spit, to breach the offshore city's defensive impregnability. We elucidate a three-phase geomorphological model for the spit's evolution. Settled since the Bronze Age, the area's geological record manifests a long history of natural and anthropogenic forcings. (i) Leeward of the island breakwater, the maximum flooding surface (e.g., drowning of the subaerial land surfaces by seawater) is dated ≈8000 B.P. Fine-grained sediments and brackish and marine-lagoonal faunas translate shallow, low-energy water bodies at this time. Shelter was afforded by Tyre's elongated sandstone reefs, which acted as a 6-km natural breakwater. (ii) By 6000 B.P., sea-level rise had reduced the dimensions of the island from 6 to 4 km. The leeward wave shadow generated by this island, allied with high sediment supply after 3000 B.P., culminated in a natural wave-dominated proto-tombolo within 1–2 m of mean sea level by the time of Alexander the Great (4th century B.C.). (iii) After 332 B.C., construction of Alexander's causeway entrained a complete anthropogenic metamorphosis of the Tyrian coastal system. PMID:17517668

  4. "In the Footsteps of Alexander the Great" PBS Series. Teacher's Guide.

    ERIC Educational Resources Information Center

    Corporation for Public Broadcasting, Washington, DC.

    This teacher's guide correlates with the Public Broadcasting Service (PBS) television series "In the Footsteps of Alexander the Great" hosted by historian Michael Wood. The four episodes of the series are entitled: "Son of God"; "Lord of Asia"; "Across the Hindu Kush"; and "To the Ends of the Earth." The guide consists of four core units related…

  5. Alexander Cameron Rutherford: A Gentleman and a Scholar. Documents in the Classroom.

    ERIC Educational Resources Information Center

    Hodysh, Henry W.

    2000-01-01

    Provides information about Alexander Cameron Rutherford, a provincial politician. Includes a letter written by Rutherford in 1912 that provides insights into his responsibilities to the general public, information about Rutherford himself, the economic conditions of Alberta, Canada in 1912, and information about the individual to whom it was…

  6. The effect of Alexander technique training program: A qualitative study of ordinary behavior application

    PubMed Central

    Kim, Soo-Yeon; Baek, Soon Gi

    2014-01-01

    The purpose of this study was to configure and apply the Alexander technique training program and assess the effect of program through physical, emotional and behavioral aspects. To achieve the research aims, qualitative research method had been conducted, subjecting 8 people, who were participating in Alexander Technique training program for this study. The study used focus group interview method for collecting date and employed for the interview method by mixing the semi-structured and unstructured questionnaire. The results were followings. First, one could develop body awareness and body consciousness through experiencing lived bodily sensation. Second, from Alexander Technique training program, people experienced psycho & physical’s equilibrium. Third, one could change not only the manner of use of body but also the attitude to the life from conscious attention to daily ordinary movement. The results provided empirical evidence of Alexander Technique training program’s functions in terms of physical, emotional and behavioral aspect through the process of consciousness control from lived body education. PMID:25610819

  7. Connect the Book. Always Inventing: A Photobiography of Alexander Graham Bell

    ERIC Educational Resources Information Center

    Brodie, Carolyn S.

    2004-01-01

    Cell phones, video phones, voice messaging?one wonders what Alexander Graham Bell would have thought about the many venues today for electronic communication with one another. Bell's March 10, 1876 invention is now 128 years old, but there is no doubt that Bell's "talking machine" changed the world. This article presents a brief review of the…

  8. Friendly Letters on the Correspondence of Helen Keller, Anne Sullivan, and Alexander Graham Bell.

    ERIC Educational Resources Information Center

    Blatt, Burton

    1985-01-01

    Excerpts from the letters between Alexander Graham Bell and Anne Sullivan and Helen Keller are given to illustrate the educational and personal growth of Helen Keller as well as the educational philosophy of Bell regarding the education of the deaf blind. (DB)

  9. Popular Response to Public Education in the Reign of Tsar Alexander I (1801-1825).

    ERIC Educational Resources Information Center

    Walker, Franklin A.

    1984-01-01

    Tsar Alexander I of Russia created a ministry of public education and promulgated laws to provide elementary and secondary schools and higher education institutions for all classes of the population. The public took a great interest in education and actively participated in the funding of schools at every level. (RM)

  10. Holocene morphogenesis of Alexander the Great's isthmus at Tyre in Lebanon

    NASA Astrophysics Data System (ADS)

    Marriner, Nick; Morhange, Christophe; Meulé, Samuel

    2007-05-01

    In 332 B.C., Alexander the Great constructed an ≈1,000-m-long causeway to seize the offshore island of Tyre. The logistics behind this engineering feat have long troubled archaeologists. Using the Holocene sedimentary record, we demonstrate that Alexander's engineers cleverly exploited a shallow proto-tombolo, or sublittoral sand spit, to breach the offshore city's defensive impregnability. We elucidate a three-phase geomorphological model for the spit's evolution. Settled since the Bronze Age, the area's geological record manifests a long history of natural and anthropogenic forcings. (i) Leeward of the island breakwater, the maximum flooding surface (e.g., drowning of the subaerial land surfaces by seawater) is dated ≈8000 B.P. Fine-grained sediments and brackish and marine-lagoonal faunas translate shallow, low-energy water bodies at this time. Shelter was afforded by Tyre's elongated sandstone reefs, which acted as a 6-km natural breakwater. (ii) By 6000 B.P., sea-level rise had reduced the dimensions of the island from 6 to 4 km. The leeward wave shadow generated by this island, allied with high sediment supply after 3000 B.P., culminated in a natural wave-dominated proto-tombolo within 1-2 m of mean sea level by the time of Alexander the Great (4th century B.C.). (iii) After 332 B.C., construction of Alexander's causeway entrained a complete anthropogenic metamorphosis of the Tyrian coastal system.

  11. Russia's Literary Genius Alexander Pushkin: The Great-Grandson of an African Slave.

    ERIC Educational Resources Information Center

    Lounsbery, Anne

    2000-01-01

    Alexander Pushkin, Russia's most celebrated literary figure, descended from an African slave. On both parents' sides, he was related to Avram Petrovich Gannibal, who was born to an African prince and abducted to become a slave to a Russian diplomat. Pushkin chose to pride himself on both his aristocratic life and his African ancestry. (SM)

  12. Alexander Bain's CUE in the Post-Modern World: Unity Revisited.

    ERIC Educational Resources Information Center

    Dryden, Phyllis

    In 1866, Alexander Bain proposed that by evaluating unity, coherence, and emphasis (which he brought together under the acronym "CUE"), students could judge the effectiveness of their written paragraphs. One hundred twenty-five years later, the proposition is still central to composition instruction. A review of modern writing textbooks reveals…

  13. Charles Alexander Eastman's "From the Deep Woods to Civilization" and the Shaping of Native Manhood

    ERIC Educational Resources Information Center

    Bayers, Peter L.

    2008-01-01

    Malea Powell has argued that Charles Alexander Eastman "imagined new possibilities for Native resistance and survival in the face of violent assimilation strategies." To Eastman, Natives had little choice but to acculturate to white society if they were going to resist white domination and survive. But gaining full equality in U.S. society proved…

  14. 76 FR 54800 - Sandy Alexander, Clifton, NJ; Notice of Negative Determination on Reconsideration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-02

    ... Employment and Training Administration Sandy Alexander, Clifton, NJ; Notice of Negative Determination on... (subject firm). The Department's Notice was published in the Federal Register on February 2, 2011 (76 FR... resulted in a negative determination based on the findings that the petitioning worker group did not...

  15. A Disciplinary Immigrant. Alexander Smith at the University of Chicago, 1894-1911

    ERIC Educational Resources Information Center

    Cotter, Donald

    2008-01-01

    The publication in 1906 of Alexander Smith's "Introduction to general inorganic chemistry" inaugurated a decisive change in chemical pedagogy in the US, the effects of which are still evident. The nature and extent of Smith's innovations are described through a comparison of his text to its source material and contemporaries. His authoritative…

  16. Old Age, the Ancient Military, and Alexander's Army: Positive Examples for a Graying America.

    ERIC Educational Resources Information Center

    Kebric, Robert B.

    1988-01-01

    Presents examples from ancient Greece and Rome illustrating working aged and intergenerational dependence. Describes normal active participation of elderly as officers and common soldiers in ancient military as example of their capabilities. Notes that Alexander the Great's army, in particular, depended on contributions of older men. (Author/NB)

  17. Obituary: Alexander (Andy) Franz Lubenow, 1956-2005

    NASA Astrophysics Data System (ADS)

    Buie, Marc William

    2006-12-01

    Alexander (Andy) Franz Lubenow, Program Coordinator at the Space Telescope Science Institute, was diagnosed with cancer of the gallbladder, pancreas, and liver in May 2005 and died on 29 September 2005. He was forty-nine. Andy was born to Bodo and Helen Lubenow in St. Paul, Minnesota on 4 January 1956. In 1964 at the age of eight, he moved with his family to Buenos Aires, Argentina, and attended the American Community School there until returning with his family in 1973 to St. Paul. Argentina had a big impact on Andy's future as an astronomer. He later recalled how he had observed and was puzzled by the "upside-down" appearance of the Moon in the southern hemisphere. In Argentina, he built his first telescope using a mirror he had ground himself. He never parted ways with that instrument. Andy did not follow a standard educational track. He spent two years at St. Olaf College in Northfield, Minnesota, before transferring to the University of Minnesota, where he earned his bachelor's degree and began work towards a master's degree in astrophysics. Later he transferred to the University of Illinois at Urbana-Champaign, where he remained until Dr. Peter Stockman hired him to work on the Hubble Space Telescope project. While in school, he worked as a teacher's assistant, taught night school, and gave demonstrations of stargazing. He was an excellent teacher and had a flair for writing. He later wrote articles for a sailing magazine and a pilot's magazine. Andy was a very practical, meticulous, and steady worker, attributes that he combined with an understated and dry sense of humor. He was always able to find a way through a problem, no matter how sticky. If a job required him to roll up his sleeves and get it done through hard work, he would persevere. Nevertheless, he was always on the lookout for an easier way. He had no patience for being forced to deal with stupid things for stupid reasons. At work at the Space Telescope Science Institute (STScI), Andy was

  18. The Use of "Ability" Measures as Controls for Concurrent or Subsequent Achievement (Comment on Alexander et al., ASR, October 1981).

    ERIC Educational Resources Information Center

    Coleman, James S.

    1982-01-01

    Comments upon a 1981 article by Alexander, Pallas, and Cook. Discusses whether particular standardized tests measure achievement or ability and the implications of this issue for school effects research. (GC)

  19. Paleozoic paleomagnetism and northward drift of the Alexander Terrane, southeastern Alaska

    NASA Astrophysics Data System (ADS)

    van Der Voo, Rob; Jones, Meridee; Gromme, C. Sherman; Eberlein, G. Donald; Churkin, Michael, Jr.

    1980-10-01

    Paleozoic limestone, graywacke, sandstone, milestone, red beds and volcanic rocks of the Alexander terrane, southeastern Alaska, have yielded six paleomagnetic pole positions after thermal and alternating-field demagnetization. These poles are from sample groups of late Middle Ordovician, Late Ordovician, Devonian, Late Devonian, and early and late Carboniferous age. To test various tectonic models for the structural development of this part of western North America, the paleomagnetic results are compared to those for the North American craton. It is found that the observed inclination and declination values deviate significantly from the values predicted for the present-day position of the Alexander terrane (55.5N, 133.5W). Better matching can be obtained for a paleoposition of the terrane at about 40N, 120W, in the present position of western Nevada and northeastern California. In addition, an in situ 25° clockwise rotation of the terrane is required to restore it to its original position.

  20. An Ice Age Refugium for Large Mammals in the Alexander Archipelago, Southeastern Alaska

    NASA Astrophysics Data System (ADS)

    Heaton, Timothy H.; Talbot, Sandra L.; Shields, Gerald F.

    1996-09-01

    Genetic and paleontological evidence are combining to provide a new and surprising picture of mammalian biogeography in southeastern Alaska. Prior to our study, the brown and black bears of the Alexander Archipelago were considered postglacial immigrants that never had overlapping ranges. Vertebrate fossils from caves on Prince of Wales Island now demonstrate that brown and black bears coexisted there (and even inhabited the same caves) both before and after the last glaciation. Differences in mtDNA sequences suggest that living brown bears of the Alexander Archipelago comprise a distinct clade and are more closely related to polar bears than to their mainland conspecifics. We conclude that brown bears, and perhaps other large mammals, have continuously inhabited the archipelago for at least 40,000 yr and that habitable refugia were therefore available throughout the last glaciation.

  1. Pennsylvanian pluton stitching of Wrangellia and the Alexander terrane, Wrangell Mountains, Alaska

    SciTech Connect

    Gardner, M.C.; Bergman, S.C.; Cushing, G.W. ); Plafker, G. ); Campbell, R.B.; Dodds, C.J. ); McClelland, W.C. ); Mueller, P.A. ); MacKevett, E.M. Jr.

    1988-11-01

    A quartz monzonite-syenite-alkali granite plutonic complex in eastern Alaska crosscuts the contact of the Alexander terrane and Wrangellia and intrudes the basement rocks of both terranes. Zircon U-Pb data indicate an intrusion age of 309 {plus minus} 5 Ma (Middle Pennsylvanian) for the pluton, and {sup 40}K-{sup 40}Ar age for hornblende separates indicate cooling to about 450 C during Middle Pennsylvanian-Early Permian time. The new field relations and age data demonstrate the Wrangellia and the Alexander terrane were contiguous during the Middle Pennsylvanian. This conclusion provides an important new constraint on paleogeographic reconstructions of the northwest Cordillera, and necessitates reassessment of stratigraphic and paleomagnetic data that were cited as evidence that the terranes evolved separately until the late Mesozoic.

  2. Paleozoic paleomagnetism and northward drift of the Alexander terrane, southeastern Alaska.

    USGS Publications Warehouse

    Van Der Voo, R.; Jones, M.; Gromme, C.S.; Eberlein, G.D.; Churkin, M., Jr.

    1980-01-01

    Paleozoic limestone, greywacke, sandstone, mudstone, red beds and volcanic rocks of the Alexander terrane, SE Alaska, have yielded six paleomagnetic pole positions after thermal and alternating-field demagnetization. These poles are from sample groups of late Middle Ordovician, Late Ordovician, Devonian, Late Devonian, and early and late Carboniferous age. To test various tectonic models for the structural development of this part of western N America, the paleomagnetic results are compared to those for the N American craton. It is found that the observed inclination and declination values deviate significantly from the values predicted for the present-day position of the Alexander terrance (55.5 N, 133.5 W). Better matching can be obtained for a paleoposition of the terrane at about 40 N, 120 W, in the present position of western Nevada and NE California. In addition, an in situ 25o clockwise rotation of the terrane is required to restore it to its original position.-Authors

  3. Clinical Experience in Late Antiquity: Alexander of Tralles and the Therapy of Epilepsy

    PubMed Central

    Bouras-vallianatos, Petros

    2014-01-01

    Alexander of Tralles, writing in the late sixth century, combined his wide-ranging practical knowledge with earlier medical theories. This article shows how clinical experience is used in Alexander’s works by concentrating on his therapeutic advice on epilepsy and, in particular, on pharmacology and the group of so-called natural remedies. I argue that clinical testing is used not only for the introduction of new medicines but also as an instrument for checking the therapeutic effect of popular healing practices. On another level, this article discusses Alexander’s role as the author of a medical compendium; it suggests that by marking the cases of clinical testing with a set of recurrent expressions, Alexander leads his audience to reflect on his medical authority and personal contribution. PMID:25045178

  4. [Physician of Obukhov school (90 years of the birth of Alexander Nikolayevich Senenko)].

    PubMed

    Simonenko, V B

    2012-01-01

    At the beginning of December 2011 turns the 90th anniversary of a prominent national physician Alexander Nikolayevich Senenko. He was an educatee of the two academies--Military Medical Kirov (graduated with honors in March 1944) and the Naval Medical (VMMA), where he studied at post-graduate at the Department of Faculty Therapy (1950-1953). The results of the scientific work of the department summarized in the monograph of Gogin E.E., Senenko A.N., Tyurin E.I., "Arterial Hypertension" (1978, 1983). Monograph of Senenko A.N. "Heart and focal infection" (1973) has not lost its scientific and practical importance to this day. Shortly before the death (June 1, 1991), Alexander Nikolaevich completed the major work on the role of focal infection in the pathology of internal organs. In all he published over 250 scientific papers, including one textbook, four monographs and several major textbooks. PMID:22545454

  5. Scaphopoda from the Alexander Terrane, Southeast Alaska-The first occurrence of Scaphopoda in the Silurian

    USGS Publications Warehouse

    Rohr, D.M.; Blodgett, R.B.; Baichtal, J.

    2006-01-01

    The scaphopods Dentalium hecetaensis n. sp. and Rhytiodentalium cf. kentuckyensis Pojeta et Runnegar, 1979, are described from Ludlow-age strata of the Heceta Limestone on Prince of Wales Island, Southeast Alaska. This is the first occurrence of Silurian scaphopods known to date. They are part of a diverse macrobenthic fauna of the Alexander terrane, an accreted southern Alaskan terrane of Siberian or Uralian affinities. ?? 2006 Nanjing Institute of Geology and Palaeontology, CAS.

  6. Professor Robert McNeill Alexander CBE FRS (1934-2016).

    PubMed

    Ker, Robert F

    2016-07-01

    Robert McNeill Alexander, known to friends and colleagues as 'Neill', was a zoologist with an engineer's eye for how animals work. He used mathematical models to show how evolution has produced optimal designs. His skill was to choose appropriate models: realistic enough to contain the essence of a problem and yet simple enough to be tractable. He wrote fluently and easily: 23 books, 280 papers and a CD-ROM entitled How Animals Move. PMID:27385751

  7. PLC/PRF/5 (Alexander) hepatoma cell line: further characterization and studies of infectivity.

    PubMed Central

    Daemer, R J; Feinstone, S M; Alexander, J J; Tully, J G; London, W T; Wong, D C; Purcell, R H

    1980-01-01

    The Alexander hepatoma cell line, PLC/PRF/5, was studied for evidence of hepatitis B virus markers and alpha-fetoprotein. Only hepatitis B surface antigen and alpha-fetoprotein were detected. Induction experiments with 5-iodo-2'-deoxyuridine and inoculation of chimpanzees with whole cells or tissue culture fluid did not reveal evidence of synthesis of additional hepatitis B virus markers or of production of infectious virus. Images Fig. 1 Fig. 2 Fig. 3 PMID:6160110

  8. Alexander H. Leighton's and Jane Murphy's scientific contributions in psychiatric epidemiology: a personal appreciation.

    PubMed

    Tremblay, Marc-Adélard

    2006-03-01

    This article introduces the special issue of Transcultural Psychiatry in honour of Alexander Leighton. A sketch of his research career is followed by a discussion of the work of his wife, Dr. Jane Murphy, first on St. Lawrence Island, near the Bering Strait, and later as a key figure in the Stirling County project. A brief conclusion highlights the main aspects of their joint legacy to cultural psychiatry and psychiatric epidemiology. PMID:16671389

  9. Teachers' professional development needs and current practices at the Alexander Science Center School

    NASA Astrophysics Data System (ADS)

    Gargus, Gerald Vincent

    This investigation represents an in-depth understanding of teacher professional development at the Alexander Science Center School, a dependent charter museum school established through a partnership between the California Science Center and Los Angeles Unified School District. Three methods of data collection were used. A survey was distributed and collected from the school's teachers, resulting in a prioritized list of teacher professional development needs, as well as a summary of teachers' opinions about the school's existing professional development program. In addition, six key stakeholders in the school's professional development program were interviewed for the study. Finally, documents related to the school's professional development program were analyzed. Data collected from the interviews and documents were used to develop an understand various components of the Alexander Science Center School's professional development program. Teachers identified seven areas that had a high-priority for future professional development including developing skills far working with below-grade-level students, improving the analytical skills of student in mathematics, working with English Language Learners, improving students' overall reading ability levels, developing teachers' content-area knowledge for science, integrating science across the curriculum, and incorporating hands-on activity-based learning strategies to teach science. Professional development needs identified by Alexander Science Center School teachers were categorized based on their focus on content knowledge, pedagogical content knowledge, or curricular knowledge. Analysis of data collected through interviews and documents revealed that the Alexander Science Center School's professional development program consisted of six venues for providing professional development for teachers including weekly "banked time" sessions taking place within the standard school day, grade-level meetings, teacher support

  10. Origin of Silurian reefs in the Alexander Terrane of southeastern Alaska

    SciTech Connect

    Soja, C.M. )

    1991-04-01

    Lower to Upper Silurian (upper Llandovery-Ludlow) limestones belonging to the Heceta Formation record several episodes of reef growth in the Alexander terrane of southeastern Alaska. As the oldest carbonates of wide-spread distribution in the region, the Heceta limestones represent the earliest development of a shallow-marine platform within the Alexander arc and the oldest foundation for reef evolution. These deposits provide important insights into the dynamic processes, styles, and bathymetry associated with reef growth in tectonically active oceanic islands. Massive stromatoporoids, corals, and red algae are preserved in fragmental rudstones and represent a fringing reef that formed at the seaward edge of the incipient marine shelf. Accessory constituents in this reef include crinoids and the cyanobacterium Girvanella. Small biostromes were constructed by ramose corals and stromatoporoids on oncolitic substrates in backreef or lagoonal environments. These buildups were associated with low-diversity assemblages of brachiopods and with gastropods, amphiporids, calcareous algae and cyanobacteria. Microbial boundstones reflect the widespread encrustation of cyanobacteria and calcified microproblematica on shelly debris as stromatolitic mats that resulted in the development of a stromatactoid-bearing mud mound and a barrier reef complex. Epiphytaceans, other microbes, and aphrosalpingid sponges were the primary frame-builders of the barrier reefs. These buildups attained significant relief at the shelf margin and shed detritus as slumped blocks and debris flows into deep-water sites along the slope. The similarity of these stromatolitic-aphrosalpingid reefs to those from Siluro-Devonian strata of autochthonous southwestern Alaska suggests paleobiogeographic ties of the Alexander terrane to cratonal North America during the Silurian.

  11. Ultrastructure of the tegument of Metamicrocotyla macracantha (Alexander, 1954) Koratha, 1955 (Monogenea, Microcotylidae).

    PubMed

    Cohen, S C; Kohn, A; Baptista-Farias, M F

    2004-02-01

    The ultrastructure of the body tegument of Metamicrocotyla macracantha (Alexander, 1954) Koratha, 1955, parasite of Mugil liza from Brazil, was studied by transmission electron microscopy. The body tegument is composed of an external syncytial layer, musculature, and an inner layer containing tegumental cells. The syncytium consists of a matrix containing three types of body inclusions and mitochondria. The musculature is constituted of several layers of longitudinal and circular muscle fibers. The tegumental cells present a well-developed nucleus, cytoplasm filled with ribosomes, rough endoplasmatic reticulum and mitochondria, and characteristic organelles of tegumental cells. PMID:15195361

  12. Alexander Disease

    MedlinePlus

    ... there are no ethnic, racial, geographic, or cultural/economic differences in its distribution. Is there any treatment? ... Fax: 815-748-0844 Prepared by: Office of Communications and Public Liaison National Institute of Neurological Disorders ...

  13. Trace element analysis of Alexander the Great's silver tetradrachms minted in Macedonia

    NASA Astrophysics Data System (ADS)

    Kallithrakas-Kontos, N.; Katsanos, A. A.; Touratsoglou, J.

    2000-11-01

    The coinage of Alexander the Great presents a special interest because of its international character in the frame of the ancient times. At least 31 mints (from Aigai to Babylon and from Pella to Alexandreia) operated in the vast state, which was created by Alexander in just over 10 years (334-323 BC). Impressive quantities of tetradrachms were consequently minted for the economic affairs of an expanding state. The mints continued to be active and after the premature death of the Macedonian king, producing among others and tetradrachms in his name. The elemental chemical composition of silver tetradrachms minted in Amphipolis as well as in other Macedonian Greek cities was analysed by energy dispersive X-ray fluorescence (EDXRF), and 12 elements were determined. The problem of the patina (silver corrosion layer) effects on the results was examined by analysis before and after the corrosion product removal. From the results of the chemical composition, a similar numismatic policy is deduced for all the analysed coin as well as metal provenance indications for some of the coins.

  14. Possible refugia in the Alexander Archipelago of southeastern Alaska during the late Wisconsin glaciation

    USGS Publications Warehouse

    Carrara, P.E.; Ager, T.A.; Baichtal, J.F.

    2007-01-01

    The interpretation of the extent of late Wisconsin glaciation in southeastern Alaska has varied between geologists and biologists. Maps and reports of the region prepared by geologists commonly indicated that late Wisconsin ice extended as a large uniform front west to the edge of the continental shelf. However, the distribution of plants and animals in the region has led many biologists to suggest that there may have been ice-free areas that served as refugia during the late Wisconsin. Based on analyses of aerial photographs, topographic maps, and bathymetric charts, in conjunction with a review of previous literature and reconnaissance fieldwork throughout the region, this study presents data supporting a limited ice extent in the Alexander Archipelago during the late Wisconsin and identifies possible ice-free areas that may have served as refugia. These areas include (1) the Fairweather Ground, (2) the Herbert Graves Island area, (3) the western coast of southern Baranof Island and adjacent continental shelf, (4) Coronation Island and the adjacent continental shelf, (5) the Warren Island area, (6) the continental shelf from west of Heceta Island to Forrester Island in the south, (7) parts of the west coast of southern Dall Island, and (8) lowland areas in southern Prince of Wales Island. The identification of these possible refugia has bearing on the recolonization of the Alexander Archipelago, as they could have served as centers of biotic dispersal upon regional deglaciation and as stepping stones for early humans with a maritime tradition entering the western hemisphere from Asia. ?? 2007 NRC Canada.

  15. Geohydrology and water-chemistry of the Alexander Valley, Sonoma County, California

    USGS Publications Warehouse

    Metzger, Loren F.; Farrar, Christopher D.; Koczot, Kathryn M.; Reichard, Eric G.

    2006-01-01

    This study of the geohydrology and water chemistry of the Alexander Valley, California, was done to provide an improved scientific basis for addressing emerging water-management issues, including potential increases in water demand and changes in flows in the Russian River. The study tasks included (1) evaluation of existing geohydrological, geophysical, and geochemical data; (2) collection and analysis of new geohydrologic data, including subsurface lithologic data, ground-water levels, and streamflow records; and (3) collection and analysis of new water-chemistry data. The estimated total water use for the Alexander Valley for 1999 was approximately 15,800 acre-feet. About 13,500 acre-feet of this amount was for agricultural use, primarily vineyards, and about 2,300 acre-feet was for municipal/industrial use. Ground water is the main source of water supply for this area. The main sources of ground water in the Alexander Valley are the Quaternary alluvial deposits, the Glen Ellen Formation, and the Sonoma Volcanics. The alluvial units, where sufficiently thick and saturated, comprise the best aquifer in the study area. Average recharge to the Alexander Valley is estimated from a simple, basinwide water budget. On the basis of an estimated annual average of 298,000 acre-feet of precipitation, 160,000 acre-feet of runoff, and 113,000 to 133,000 acre-feet of evapotranspiration, about 5,000 to 25,000 acre-feet per year is available for ground-water recharge. Because this estimate is based on differences between large numbers, there is significant uncertainty in this recharge estimate. Long-term changes in ground-water levels are evident in parts of the study area, but because of the sparse network and lack of data on well construction and lithology, it is uncertain if any significant changes have occurred in the northern part of the study area since 1980. In the southern half of the study area, ground-water levels generally were lower at the end of the 2002 irrigation

  16. Speciation despite globally overlapping distributions in Penicillium chrysogenum: the population genetics of Alexander Fleming’s lucky fungus

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Eighty years ago, Alexander Fleming described the antibiotic effects of a fungus that had contaminated his bacterial culture, kick starting the antimicrobial revolution. The fungus was later ascribed to a globally distributed asexual species, Penicillium chrysogenum. Recently, the species has been...

  17. Growing Community: The Impact of the Stephanie Alexander Kitchen Garden Program on the Social and Learning Environment in Primary Schools

    ERIC Educational Resources Information Center

    Block, Karen; Gibbs, Lisa; Staiger, Petra K.; Gold, Lisa; Johnson, Britt; Macfarlane, Susie; Long, Caroline; Townsend, Mardie

    2012-01-01

    This article presents results from a mixed-method evaluation of a structured cooking and gardening program in Australian primary schools, focusing on program impacts on the social and learning environment of the school. In particular, we address the Stephanie Alexander Kitchen Garden Program objective of providing a pleasurable experience that has…

  18. Dr. Charles Alexander Eastman, Sioux Physician-Author, 1858-1939. With Teacher's Guide. Native Americans of the Twentieth Century.

    ERIC Educational Resources Information Center

    Minneapolis Public Schools, MN.

    A biography for elementary school students of a 19th century American Indian physician and author, Charles Alexander Eastman (Sioux), includes photographs of Dr. Eastman and his wife. A teacher's guide following the bibliography contains information on the Sioux Uprising of 1862 and the Wounded Knee Massacre, learning objectives and directions for…

  19. The Four Domains of Moral Education: The Contributions of Dewey, Alexander and Goleman to a Comprehensive Taxonomy.

    ERIC Educational Resources Information Center

    Zigler, Ronald Lee

    1998-01-01

    Attempts to place a neglected dimension of John Dewey's work into its proper context. Examines the works of Dewey, F. Matthias Alexander, and Daniel Goldman to create four domains that must be addressed by a truly comprehensive model of moral education: direct external, indirect external, direct internal, and indirect internal. (DSK)

  20. On the Social Psychology of Higher Education: A Bibliography of Alexander W. Astin. Public Administration Series Bibliography, P-688.

    ERIC Educational Resources Information Center

    Quay, Richard H.

    A bibliography of articles by Alexander W. Astin on the social psychology of higher education is presented. Entries are presented by year, starting with 1980 and dating back to 1956. Topics that are covered include: equal access to higher education, student persistence and attrition, higher education policy, selective admissions and open…

  1. Reliance on Arbitral Awards in Title VII Suits: Implications of Alexander v. Gardner-Denver and Public Employment Cases

    ERIC Educational Resources Information Center

    Miller, David R.

    1976-01-01

    The 1974 Supreme Court decision in Alexander v. Gardner-Denver Co. resolved the controversy in the lower courts concerning the finality of an arbitration award when concurrent or subsequent court action is brought under Title VII. For journal availability see HE 508 844. (LBH)

  2. Bryan Coast, English Coast, Alexander Island, Fallieres Coast, and Bellingshausen Sea, Antarctica

    NASA Technical Reports Server (NTRS)

    2002-01-01

    This image of Antarctica shows the Bryan Coast (lower left), the English Coast (lower central), Alexander Island (middle right), the Fallieres Coast (top right), and the Bellingshausen Sea. The entire continent has been dedicated to peaceful scientific investigation since 1961, with the signing of the Antarctic Treaty.The waters surrounding Antarctica are intensely cold. Salt water freezes at -2C, allowing sea ice to form. The middle left portion of the image shows quite a lot of sea ice in the Bellingshausen Sea. During the Antarctic winter, when data for this image was acquired, Antarctica doubles in size to about 28.5 million square km (or about 11 million square miles), and temperatures in the -60C range are common.This true-color image was compiled from MODIS data gathered March 29, 2002. Credit: Jacques Descloitres, MODIS Land Rapid Response Team, NASA/GSFC

  3. Effects of traumatic brain injury on reactive astrogliosis and seizures in mouse models of Alexander disease

    PubMed Central

    Cotrina, Maria Luisa; Chen, Michael; Han, Xiaoning; Iliff, Jeffrey; Ren, Zeguang; Sun, Wei; Hagemann, Tracy; Goldman, James; Messing, Albee; Nedergaard, Maiken

    2014-01-01

    Alexander disease (AxD) is the only known human pathology caused by mutations in an astrocyte-specific gene, glial fibrillary acidic protein (GFAP). These mutations result in abnormal GFAP accumulations that promote seizures, motor delays and, ultimately, death. The exact contribution of increased, abnormal levels of astrocytic mutant GFAP in the development and progression of the epileptic phenotype is not clear, and we addressed this question using two mouse models of AxD. Comparison of brain seizure activity spontaneously and after traumatic brain injury (TBI), an effective way to trigger seizures, revealed that abnormal GFAP accumulation contributes to abnormal brain activity (increased interictal discharges) but is not a risk factor for the development of epilepsy after TBI. These data highlight the need to further explore the complex and heterogeneous response of astrocytes towards injury and the involvement of GFAP in the progression of AxD. PMID:25069089

  4. Finding revelation in anthropology: Alexander Winchell, William Robertson Smith and the heretical imperative.

    PubMed

    Livingstone, David N

    2015-09-01

    Anthropological inquiry has often been considered an agent of intellectual secularization. Not least is this so in the sphere of religion, where anthropological accounts have often been taken to represent the triumph of naturalism. This metanarrative, however, fails to recognize that naturalistic explanations could sometimes be espoused for religious purposes and in defence of confessional creeds. This essay examines two late nineteenth-century figures--Alexander Winchell in the United States and William Robertson Smith in Britain--who found in anthropological analysis resources to bolster rather than undermine faith. In both cases these individuals found themselves on the receiving end of ecclesiastical censure and were dismissed from their positions at church-governed institutions. But their motivation was to vindicate divine revelation, in Winchell's case from the physical anthropology of human origins and in Smith's from the cultural anthropology of Semitic ritual. PMID:26256313

  5. Neuromusicology or Musiconeurology? "Omni-art" in Alexander Scriabin as a Fount of Ideas.

    PubMed

    Triarhou, Lazaros C

    2016-01-01

    Science can uncover neural mechanisms by looking at the work of artists. The ingenuity of a titan of classical music, the Russian composer Alexander Scriabin (1872-1915), in combining all the sensory modalities into a polyphony of aesthetical experience, and his creation of a chord based on fourths rather than the conventional thirds are proposed as putative points of departure for insight, in future studies, into the neural processes that underlie the perception of beauty, individually or universally. Scriabin's "Omni-art" was a new synthesis of music, philosophy and religion, and a new aesthetic language, a unification of music, vision, olfaction, drama, poetry, dance, image, and conceptualization, all governed by logic, in the quest for the integrative action of the human mind toward a "higher reality" of which music is only a component. PMID:27014167

  6. Neuromusicology or Musiconeurology? “Omni-art” in Alexander Scriabin as a Fount of Ideas

    PubMed Central

    Triarhou, Lazaros C.

    2016-01-01

    Science can uncover neural mechanisms by looking at the work of artists. The ingenuity of a titan of classical music, the Russian composer Alexander Scriabin (1872–1915), in combining all the sensory modalities into a polyphony of aesthetical experience, and his creation of a chord based on fourths rather than the conventional thirds are proposed as putative points of departure for insight, in future studies, into the neural processes that underlie the perception of beauty, individually or universally. Scriabin’s “Omni-art” was a new synthesis of music, philosophy and religion, and a new aesthetic language, a unification of music, vision, olfaction, drama, poetry, dance, image, and conceptualization, all governed by logic, in the quest for the integrative action of the human mind toward a “higher reality” of which music is only a component. PMID:27014167

  7. The name of the father: conflict between Louis and Alexander Agassiz and the Embiotoca surfperch radiation.

    PubMed

    Bernardi, G

    2009-04-01

    The surfperch genus Embiotoca currently comprises two species, Embiotoca jacksoni, the black surfperch, and Embiotoca lateralis, the striped surfperch. Originally, however, Louis Agassiz described a third species in the genus Embiotoca, the rainbow surfperch, Embiotoca caryi. This latter name was changed by Louis' son, Alexander, to Hypsurus caryi, a name that remains valid. In this study, new molecular data (3545 bp of DNA from four mitochondrial and two nuclear DNA regions) indicated that the rainbow surfperch should be retained within the genus Embiotoca, a result consistent with recent morphological data. Adaptive radiation combined with sexual selection resulting in rapid morphological changes in the rainbow surfperch may have contributed to the conflicting position of this species. PMID:20735618

  8. Alteration of glial-neuronal metabolic interactions in a mouse model of Alexander disease

    PubMed Central

    Meisingset, Tore Wergeland; Risa, Øystein; Brenner, Michael; Messing, Albee; Sonnewald, Ursula

    2010-01-01

    Alexander disease is a rare and usually fatal neurological disorder characterized by the abundant presence of protein aggregates in astrocytes. Most cases result from dominant missense de novo mutations in the gene encoding glial fibrillary acidic protein (GFAP), but how these mutations lead to aggregate formation and compromise function is not known. A transgenic mouse line (Tg73.7) over-expressing human GFAP produces astrocytic aggregates indistinguishable from those seen in the human disease, making them a model of this disorder. To investigate possible metabolic changes associated with Alexander disease Tg73.7 mice and controls were injected simultaneously with [1-13C]glucose to analyze neuronal metabolism and [1,2-13C]acetate to monitor astrocytic metabolism. Brain extracts were analyzed by 1H magnetic resonance spectroscopy (MRS) to quantify amounts of several key metabolites, and by 13C MRS to analyze amino acid neurotransmitter metabolism. In the cerebral cortex, reduced utilization of [1,2-13C]acetate was observed for synthesis of glutamine, glutamate, and GABA, and the concentration of the marker for neuronal mitochondrial metabolism, N-acetylaspartate (NAA), was decreased. This indicates impaired astrocytic and neuronal metabolism and decreased transfer of glutamine from astrocytes to neurons compared to control mice. In the cerebellum, glutamine and GABA content and labeling from [1-13C]glucose were increased. Evidence for brain edema was found in the increased amount of water and of the osmoregulators myo-inositol and taurine. It can be concluded that astrocyte – neuronal interactions were altered differently in distinct regions. PMID:20544858

  9. Silurian trace fossils in carbonate turbidites from the Alexander Arc of southeastern Alaska

    SciTech Connect

    Soja, C.M. )

    1990-05-01

    Early to Late Silurian (Wenlock-Ludlow) body and trace fossils from the Heceta Formation are preserved in the oldest widespread carbonates in the Alexander terrane of southeastern Alaska. They represent the earliest shelly benthos to inhabit a diversity of marine environments and are important indicators of the early stages in benthic community development within this ancient island arc. The trace fossils are significant because they add to a small but growing body of knowledge about ichnofaunas in deep-water Paleozoic carbonates. Proximal to medial carbonate turbidites yield a low-diversity suite of trace fossils that comprises five distinct types of biogenic structures. Bedding planes reveal simple epichnial burrows (Planolites), cross-cutting burrows (Fucusopsis), and tiny cylindrical burrows. These and other casts, including chondrites( )-like burrow clusters, represent the feeding activities (fodinichnia) of preturbidite animals. Hypichnial burrows and rare endichnial traces reflect the activities of postturbidite animals. Broken and offset traces indicate that infaunal biota commenced burrowing before slumping and subsequent soft-sediment deformation. The abundance and density of trace fossils increases offshore in the medial turbidites associated with a decrease in the size and amount of coarse particles and with an increase in mud and preserved organic material. Although diversity levels are similar in the proximal and medial turbidite facies, they are much lower than in Paleozoic siliciclastic turbidites. This may reflect unfavorable environmental conditions for infaunal biota or paleobiogeographic isolation of the Alexander terrane during the Silurian. A greater use of trace fossils in terrane analysis will help to resolve this issue and should provide new data for reconstructing the paleogeography of circum-Pacific terranes.

  10. [The life history of Alexander Numan (1780-1852) during his time in Groningen].

    PubMed

    Mathijsen, A H

    2001-01-01

    Until the time Numan took on his professorship at the newly established Veterinary School in Utrecht in 1822, he had lived in the Province of Groningen. In order to understand why the minister of Public Education appointed a village doctor from the north of the country as professor for the practice of veteriary medicine, and after some years as director of the school, it was felt essential to investigate his earlier life period. The main sources used are two obituaries, resp. written by his son who was a professor of Law at Groningen University, and by his friend prof. Willem Vrolik who was the secretary of the Academy of Science, supplemented by family histories and some archival research. After a short description of his descent, youth adn education follows the main part devoted to his writings, his medical practice and membership of the Provincial Medical Commission and the Commission for Agriculture. In an appendix some genealogical data are presented on the family of his wife and their children. Alexander lost his father, who was a minister of the Reformed Church, when he was ten years old. He received his education in the circle of family members. A brother of his father, also a minister, teached him Greek and Latin. After this uncle had left the province, he lived in the home of another minister who teached him the modern languages. As this man was involved in politics of the Baravian Republic, young Alexander was exposed to many discussions on the polity of the State. After his mother had remarried with a medical doctor, this man, and also his brother who had a medical practice in another part of the province, complemented the education with an introduction in the sciences. Experiences in their dispensaries, where some knowledge of botany and chemistry could be obtained, and discussions when accompanying them on their visits to patients, were decisive in the choice of his profession. Only at the age of twenty he entered the Medical Faculty of Groningen

  11. "Outstanding Services to Negro Health": Dr. Dorothy Boulding Ferebee, Dr. Virginia M. Alexander, and Black Women Physicians' Public Health Activism.

    PubMed

    Gamble, Vanessa Northington

    2016-08-01

    An examination of the lives and careers of physician-activists Dorothy Boulding Ferebee (1898-1972) and Virginia M. Alexander (1899-1949) demonstrates how Black physicians in the first half of the 20th century used public health to improve the health of Black Americans and provides insights into the experiences of Black women physicians. I discuss their professional and personal backgrounds and analyze their divergent strategies to address health inequities. Ferebee used her leadership in Black women's organizations to develop public health programs and become a national advocate for Black health. Alexander, a Quaker, used her religious connections to urge Whites to combat racism in medicine. She also conducted public health research and connected it to health activism. Both were passionate advocates of health equity long before it gained prominence as a major public health issue. An analysis of their work illuminates past efforts to improve the health of Black Americans. PMID:27310348

  12. Alexander Scriabin: his chronic right-hand pain and Its impact on his piano compositions.

    PubMed

    Altenmüller, Eckart

    2015-01-01

    Alexander Scriabin was an outstanding pianist and an avant-garde composer who influenced later generations with his innovative "multimedia" conceptions of aesthetic experience. As an adolescent, he was systematically trained as a concert pianist and received lessons from Vassily Safonoff, one of the founders of the legendary Russian Piano School. At age 20, Scriabin suffered an overuse injury of his right hand when attempting to improve the sound quality of his piano touch. This injury caused a deep crisis and influenced his later composition style in his piano works. From this time on, his works were frequently dominated by unusual virtuosic use and wide spans of his left hand. Rest, restricted repertoire, and an increased focus on composition contributed to recovery; however, he always remained anxious concerning the stamina of his right hand. The case report impressively demonstrates the stressors an aspiring young pianist had to cope with at the end of the nineteenth century. Furthermore, it is a convincing example of how resource-oriented behavior and intuition lead to the improvement of health status. Differential diagnoses and the modern concept of multimodal pain therapy in chronic overuse injury will be discussed from a historical perspective. PMID:25684291

  13. James Alexander Lindsay (1856-1931), and his clinical axioms and aphorisms.

    PubMed

    Breathnach, Caoimhghin S; Moynihan, John B

    2012-09-01

    John Alexander Lindsay was born at Fintona, county Tyrone in 1856, and at the age of 23 he graduated in medicine at the Royal University of Ireland. After two years in London and Europe he returned to Belfast to join the staff at the Royal Victoria Hospital and in 1899 he was appointed to the professorship of medicine. He was valued by the students for his clarity and by his colleagues for his many extracurricular contributions to the medical profession in the positions entrusted to him. He published monographs on Diseases of the Lungs, and the Climatic Treatment of Consumption, but his later Medical Axioms show his deep appreciation of studied clinical observation. Although practice was changing in the new century Lindsay displayed an ability to change with the new requirements, as evidenced by his lecture on electrocardiography as president of the section of medicine of the Royal Academy of Medicine in Ireland in 1915. He was impressed by the way the string galvanometer changed attention from stenosis and incompetence of the valves to the cardiac musculature, but rightly suspected that there was more to be told about the state of the myocardium than Einthoven's three leads revealed. His death occurred in Belfast in 1931. PMID:23620615

  14. James Alexander Lindsay (1856–1931), and his clinical axioms and aphorisms

    PubMed Central

    Breathnach, Caoimhghin S; Moynihan, John B

    2012-01-01

    John Alexander Lindsay was born at Fintona, county Tyrone in 1856, and at the age of 23 he graduated in medicine at the Royal University of Ireland. After two years in London and Europe he returned to Belfast to join the staff at the Royal Victoria Hospital and in 1899 he was appointed to the professorship of medicine. He was valued by the students for his clarity and by his colleagues for his many extracurricular contributions to the medical profession in the positions entrusted to him. He published monographs on Diseases of the Lungs, and the Climatic Treatment of Consumption, but his later Medical Axioms show his deep appreciation of studied clinical observation. Although practice was changing in the new century Lindsay displayed an ability to change with the new requirements, as evidenced by his lecture on electrocardiography as president of the section of medicine of the Royal Academy of Medicine in Ireland in 1915. He was impressed by the way the string galvanometer changed attention from stenosis and incompetence of the valves to the cardiac musculature, but rightly suspected that there was more to be told about the state of the myocardium than Einthoven's three leads revealed. His death occurred in Belfast in 1931. PMID:23620615

  15. Testing the equality of students' performance using Alexander-Govern test with adaptive trimmed means

    NASA Astrophysics Data System (ADS)

    Abdullah, Suhaida; Yahaya, Sharipah Soaad Syed; Yusof, Zahayu Md

    2014-06-01

    Analyzing the equality of independent group has to be done with caution. The classical approaches such as ttest for two groups and analysis of variance (ANOVA) for more than two groups always are favorable selection by researchers. However, sometime these methods were abused by the presence of nonnormality or variance heterogeneity or both. It is known that ANOVA is restricted to the assumptions of normality and homogeneity of variance. In real life data, sometimes these requirements are hard to attain. The Alexander-Govern test with adaptive trimmed mean (AG_atm) is one approach that can be chosen as alternative to the classical tests when their assumptions are violated. In this paper, the performances of AG_atm were compared to the original AG test and ANOVA using simulated and real life data. The simulation study proved that the AG_atm performs better than the original AG test and the classical test. For real life data, student's performance in decision analysis course, measured by final examination score was chosen. Based on the exploratory data analysis, this data found to have problem of nonnormality.

  16. Death by polonium-210: lessons learned from the murder of former Soviet spy Alexander Litvinenko.

    PubMed

    McFee, Robin B; Leikin, Jerrold B

    2009-02-01

    The medical response to radiation--whether the result of radiological warfare, terrorist deployment of improvised radiation dispersal weapons, political assassination, occupational or industrial accidents or the medically radiated patient remains one of the least taught among all disciplines within medical education. In the aftermath of 9/11 among medical vulnerabilities to toxicant threats, of all the categories of weapons of mass destruction (WMD)--whether using the CBRNE (chemical, biological, radiological, nuclear, explosive) or NBC (nuclear, biological, chemical) acronym--radiation is the least taught in professional schools, responder cultures or civil preparedness organizations. To date, few health care professionals (HCP) possess the fundamental knowledge or skills to identify and diagnose, let alone treat a radiation victim; this vulnerability made even more obvious in the aftermath of the high profile assassination of former Russian agent Alexander Litvinenko. He was poisoned with Polonium210. Radioactive substances are ubiquitous with radiation sources being in or transported through virtually every region nationwide. It is essential to increase preparedness among community and rural health care facilities as well as urban and university hospitals. Managing radiation injuries effectively requires access to specialized equipment and expertise. Radiation sickness is progressive and may require acute, critical and long-term care throughout the course of illness. Regardless of the source, preparedness rests upon acknowledging a threat exists and dedicating the resources to address the risks including the enhancement of training and equipment. Mass or individual exposures to radiation present unique challenges to the entire response continuum from law enforcement, first responders and emergency medical care. Increased education about and practice in responding to radiological threats is essential to enhance preparedness. PMID:19292030

  17. Bathymetric gradients within a Paleozoic Island Arc, southeastern Alaska (Alexander Terrane)

    SciTech Connect

    Soja, C.M. )

    1990-05-01

    Early to Late Silurian (Wenlock-Ludlow) limestones belonging to the Heceta Formation reflect bathymetric gradients within the ancient island arc exposed in the Alexander terrane of southeastern Alaska. These rocks record the earliest occurrence of widespread carbonate deposition in the region and represent the earliest foundation for shallow-water platform development within the arc. The excellent preservation of platform, platform margin, and slope deposits contrasts with the poor preservation of many marine sediments that originated within other island arcs. Hence, these limestones provide important insights into the styles, processes, and bathymetry of carbonate deposition in island arcs. Carbonate depositional sites within the arc extended laterally from nearshore intertidal and relatively shallow subtidal zones of a marine platform, to the seaward margins of a rimmed shelf, and into deeper subtidal areas of a slope environment. Fossiliferous deposits that originated on the platform comprise a diversity of shelly benthos, including corals and stromatoporoids in growth position. Dasycladacean algae, oncoids, and Amphipora also indicate shallow-water conditions. Organic buildups and reefs were constructed by cyanobacteria, massive stromatoporoids, corals, and algae at the platform margin. Deposition beyond the seaward edge of the shelf is evident from the carbonate turbidites that consist of skeletal debris of shallow-water derivation and an absence of coarse siliciclastic detritus. Sedimentation and resedimentation along a bathymetric gradient within the arc is especially well illustrated by the carbonate breccias that are enclosed within these deep subtidal sediments. They comprise detached stromatolites and clasts of shallow-water origin that were derived from the platform and its margin during periodic slumping of the shelf edge.

  18. Prelude to Everest: Alexander M. Kellas and the 1920 high altitude scientific expedition to Kamet.

    PubMed

    Rodway, George W

    2004-01-01

    Following his untimely death due to illness during the early stages of the first Mount Everest Reconnaissance Expedition in 1921, Alexander M. Kellas has received relatively little attention in either mountaineering or scientific literature. He remains an obscure figure despite his noteworthy contributions to high altitude physiology and exploration. He can be considered not only one of the finest exploratory Himalayan mountaineers in history, but also the first person to apply state-of-the-art knowledge of high altitude physiology to field investigations at altitudes over 6000 m. By the time of his death, it is extremely likely that Kellas had spent more time above 6000 m than anyone on Earth, undertaking no fewer than eight Himalayan expeditions between 1907 and 1921. This article revisits and examines in some detail the most ambitious high altitude physiological field study undertaken through the second decade of the 20th century, A. M. Kellas and Henry T. Morshead's 1920 Kamet Expedition. This undertaking by Kellas and Morshead was unique because it specifically emphasized investigation of the practical difficulties inherent in climbing at very high altitudes. During this endeavor, Kellas carried out the first rigorous tests of the value of supplementary oxygen for climbing at high altitude. The results of the field studies conducted during the 1920 Kamet Expedition provided strong support for the use of supplementary oxygen at high altitude. However, after Kellas died on the approach march to Everest the following year, the British mountaineering establishment did not again have a similar proponent or exponent of extreme altitude field research until physiologist Griffith Pugh once again took up the challenge in the early 1950s. PMID:15454003

  19. Neuromechanical interference of posture on movement: evidence from Alexander technique teachers rising from a chair

    PubMed Central

    Cacciatore, Timothy W.; Mian, Omar S.; Peters, Amy

    2014-01-01

    While Alexander technique (AT) teachers have been reported to stand up by shifting weight gradually as they incline the trunk forward, healthy untrained (HU) adults appear unable to rise in this way. This study examines the hypothesis that HU have difficulty rising smoothly, and that this difficulty relates to reported differences in postural stiffness between groups. A wide range of movement durations (1–8 s) and anteroposterior foot placements were studied under the instruction to rise at a uniform rate. Before seat-off (SO) there were clear and profound performance differences between groups, particularly for slower movements, that could not be explained by strength differences. For each movement duration, HU used approximately twice the forward center-of-mass (CoM) velocity and vertical feet-loading rate as AT. For slow movements, HU violated task instruction by abruptly speeding up and rapidly shifting weight just before SO. In contrast, AT shifted weight gradually while smoothly advancing the CoM, achieving a more anterior CoM at SO. A neuromechanical model revealed a mechanism whereby stiffness affects standing up by exacerbating a conflict between postural and balance constraints. Thus activating leg extensors to take body weight hinders forward CoM progression toward the feet. HU's abrupt weight shift can be explained by reliance on momentum to stretch stiff leg extensors. AT's smooth rises can be explained by heightened dynamic tone control that reduces leg extensor resistance and improves force transmission across the trunk. Our results suggest postural control shapes movement coordination through a dynamic “postural frame” that affects the resistive behavior of the body. PMID:25085609

  20. Bokan Mountain peralkaline granitic complex, Alexander terrane (southeastern Alaska): evidence for Early Jurassic rifting prior to accretion with North America

    USGS Publications Warehouse

    Dostal, Jaroslav; Karl, Susan M.; Keppie, J. Duncan; Kontak, Daniel J.; Shellnutt, J. Gregory

    2013-01-01

    The circular Bokan Mountain complex (BMC) on southern Prince of Wales Island, southernmost Alaska, is a Jurassic peralkaline granitic intrusion about 3 km in diameter that crosscuts igneous and metasedimentary rocks of the Alexander terrane. The BMC hosts significant rare metal (rare earth elements, Y, U, Th, Zr, and Nb) mineralization related to the last stage of BMC emplacement. U–Pb (zircon) and 40Ar/39Ar (amphibole and whole-rock) geochronology indicates the following sequence of intrusive activity: (i) a Paleozoic basement composed mainly of 469 ± 4 Ma granitic rocks; (ii) intrusion of the BMC at 177 ± 1 Ma followed by rapid cooling through ca. 550 °C at 176 ± 1 Ma that was synchronous with mineralization associated with vertical, WNW-trending pegmatites, felsic dikes, and aegirine–fluorite veins and late-stage, sinistral shear deformation; and (iii) intrusion of crosscutting lamprophyre dikes at >150 Ma and again at ca. 105 Ma. The peralkaline nature of the BMC and the WNW trend of associated dikes suggest intrusion during NE–SW rifting that was followed by NE–SW shortening during the waning stages of BMC emplacement. The 177 Ma BMC was synchronous with other magmatic centres in the Alexander terrane, such as (1) the Dora Bay peralkaline stock and (2) the bimodal Moffatt volcanic suite located ~30 km north and ~100 km SE of the BMC, respectively. This regional magmatism is interpreted to represent a regional extensional event that precedes deposition of the Late Jurassic – Cretaceous Gravina sequence that oversteps the Wrangellia and Alexander exotic accreted terranes and the Taku and Yukon–Tanana pericratonic terranes of the Canadian–Alaskan Cordillera.

  1. The grand experiment, a historical account of a museum/school partnership: The Alexander Science Center School of Los Angeles

    NASA Astrophysics Data System (ADS)

    Heughins, Andrew R.

    This study tells the history of The Alexander Science Center School, a museum/school partnership between the Los Angeles Unified School District and the California Science Center created with the goal of becoming a national model in elementary science education. To provide a background to the development of the school, this study explores the definition of what constitutes a museum school, including the existence of a formal partnership between a school district and a museum and systemic change in the partner institutions leading to a marriage of formal and informal learning styles. In addition, the literature review explores the unique models of museum/school partnerships developed in the United States. The history of the Alexander Science Center School is told in a narrative style using documentation from the schools development and through interviews with individuals who played key roles, from the schools inception through its opening. The study covers the initiation of concept, architectural design, formation of the partnership, and development of the curriculum. The study also identifies the roadblocks encountered in the schools development and makes recommendations for school districts and institutions seeking to create future museum school projects. In addition, a comparison is made other recently studied museum schools to provide a context for the school's historical and programmatic development.

  2. Discuss: If Essays Are Dead, Then Where Does That Leave Everything Else? A Response to: Shirley Alexander's "Buying Essays: How to Make Sure Assessment Is Authentic"

    ERIC Educational Resources Information Center

    McQueen, Kelvin

    2015-01-01

    Professor Shirley Alexander is the Deputy Vice-Chancellor and Vice-President (Teaching, Learning & Equity) at the University of Technology, Sydney. On 12 November 2014, an article of hers appeared in "The Conversation": "Buying essays: how to make sure assessment is authentic." That article traverses, in an abbreviated way,…

  3. In vitro and in vivo cytotoxic activity of native and ricin conjugated monoclonal antibodies to HBs antigen for Alexander primary liver cell carcinoma cells and tumours.

    PubMed Central

    Oladapo, J M; Goodall, A H; de Koning, R; Parmar, J; Brown, D; Thomas, H C

    1984-01-01

    In in vitro and in vivo systems, native or ricin conjugated monoclonal anti-HBs, are capable of inhibiting or slowing the growth of Alexander primary hepatocellular carcinoma cells. Failure of the immune response to this component of the hepatitis B virus may be one permissive factor in the development of some primary liver cell carcinoma in chronic HBV carriers. PMID:6329921

  4. Alexander Graham Bell's Patent for the Telephone and Thomas Edison's Patent for the Electric Lamp. The Constitution Community: The Development of the Industrial United States (1870-1900).

    ERIC Educational Resources Information Center

    Schur, Joan Brodsky

    In 1876 Americans held a Centennial Exhibition in Philadelphia (Pennsylvania) to celebrate the nation's birth 100 years earlier. Machinery Hall drew the most admiration and wonder. Alexander Graham Bell exhibited the first telephone, and Thomas Alva Edison presented the automatic telegraph, one of more than 1,000 inventions he would patent in his…

  5. Prevention and Early Intervention: Individual Differences as Risk Factors for the Mental Health of Children. A Festschrift for Stella Chess and Alexander Thomas.

    ERIC Educational Resources Information Center

    Carey, William B., Ed.; McDevitt, Sean C., Ed.

    This collection of essays, in honor of child psychiatry pioneers Stella Chess and Alexander Thomas, focuses on their idea that important life outcomes are the product of ongoing interactions between a child's behavioral style and the complimentarity or lack of fit of the parenting environment. Following an introduction, the remaining chapters are:…

  6. The Question of Sign-Language and the Utility of Signs in the Instruction of the Deaf: Two Papers by Alexander Graham Bell (1898)

    ERIC Educational Resources Information Center

    Marschark, M.

    2005-01-01

    Alexander Graham Bell is often portrayed as either hero or villain of deaf individuals and the Deaf community. His writings, however, indicate that he was neither, and was not as clearly definite in his beliefs about language as is often supposed. The following two articles, reprinted from The Educator (1898), Vol. V, pp. 3?4 and pp. 38?44,…

  7. Linguistic Values and Religious Experience: An Analysis of the Clothing Metaphors in Alexander Richardson's Ramist-Puritan Lectures on Speech, "Speech is a garment to cloath our reason."

    ERIC Educational Resources Information Center

    Adams, John Charles

    1990-01-01

    Analyzes Alexander Richardson's clothing metaphors which connected Ramist precepts to social values and philosophic assumptions drawn from the fields of fashion, psychology, and Puritan theology. Describes how these metaphors presented the Puritan community with an orientation toward listening and inculcated the Puritan speech community with…

  8. James Sowerby: meteorites and his meteoritic sword made for the Emperor of Russia, Alexander I, in 1814

    PubMed Central

    Henderson, Paul

    2013-01-01

    James Sowerby included meteorites in his publications of British and exotic natural history and so raised interest in their nature and origins at a time of much debate and involving the President of the Royal Society, Sir Joseph Banks. The celebrations over the defeat of France in 1814 prompted Sowerby to make a sword from the Cape of Good Hope iron meteorite to present to the Russian Emperor, Alexander I, at the time of his state visit to London in June 1814 and in recognition of his achievements in bringing peace to Europe. The story of its attempted presentation, its final reception and the following response, including publications, all helped to increase interest in meteorites and their properties. The rediscovery of the sword after a lengthy disappearance probably brings an unusual saga to a fitting close.

  9. Map of glacial limits and possible refugia in the southern Alexander Archipelago, Alaska, during the late Wisconsin glaciation

    USGS Publications Warehouse

    Carrara, Paul E.; Ager, Thomas A.; Baichtal, James F.; VanSistine, D. Paco

    2003-01-01

    During the late Wisconsin glaciation (circa 26,000-13,000 carbon-14 yr BP) the Cordilleran glacier complex formed vast ice fields and large glaciers along the crest of the Coast Mountains. As these glaciers flowed west to the Pacific Ocean, they were joined by local glaciers originating on the higher reaches of the Alexander Archipelago (Mann and Hamiltion, 1995). This extensive volume of ice was channeled into deep troughs (present-day fiords) that formed major outlet glaciers, such as the glaciers that occupied Chatham Strait and Dixon Entrance. In several places along the coast, deep glacially scoured submarine troughs indicate that glaciers reached to the edge of the continental shelf. For instance, the glacier that extended into the Dixon Entrance trough is known to have extended to the edge of the continental shelf. Its retreat began sometime after 16,000-15,000 carbon-14 yr BP (Barrie and Conway, 1999).

  10. The evolution of ultrahigh carbon steels - from the Great Pyramids, to Alexander the Great, to Y2K

    SciTech Connect

    Wadsworth, J

    1999-10-01

    Hypereutectoid steels containing between about 1 and 2.1 wt%C, and now known as ultrahigh carbon steels (UHCS), have both a rich history (dating back to the time of Alexander the Great, i.e. {approximately} 300 BC) and an interesting, recent, technological period of development (from 1975 to the present). The connections between the modern UHCS and their ancient counterparts, and in particular Damascus steels, have received considerable attention. In addition to monolithic products, UHCS have also been used in both ancient and modern times in laminated composites. In the present paper, a summary of the modern development of UHCS and UHCS-containing laminates is given, and parallels are drawn with ancient materials. Also, ancient laminated composites containing other steels are described; controversial issues and a possible solution related to the age of such a laminate found in the Great Pyramid of Gizeh are discussed.

  11. The appearance of the artist to the people: the creativity, personality and malady of Alexander Ivanov (1806-58).

    PubMed

    Lerner, Vladimir; Witztum, Eliezer

    2005-02-01

    Alexander Ivanov was an outstanding Russian painter who lived in the middle of the nineteenth century, during the romantic period. He did not accept romanticism but instead tried to create his own original style, an ambitious combination of spiritual profundity and a manner of execution unparalleled in Western European art. Ivanov's intention and style are best reflected in his major work The Appearance of Christ to the People, a picture on which he worked for over 20 years. He painted more than 400 sketches of the picture while attempting to bring his masterpiece to perfection. At the end of his life Ivanov became disillusioned, renounced his strong religious conviction and became suspicious. This study examines the influence of his background, life story and personality on the creative process. From a diagnostic perspective, Ivanov's personality featured obsessive, narcissistic and schizoid traits. In his final years he suffered from a delusional disorder. PMID:15682233

  12. Forced sea-level change in a forearc basin related to subduction of a spreading ridge: the Fossil Bluff Group (Jurassic-Cretaceous), Alexander Island, Antarctic Peninsula

    NASA Astrophysics Data System (ADS)

    Macdonald, David

    2015-04-01

    During the Mesozoic, the Antarctic Peninsula was the site of an active volcanic arc related to the eastwards subduction of proto-Pacific oceanic crust. Alexander Island is the largest of the many islands that lie on the western (fore-arc) side of the Antarctic Peninsula; it forms one of the best-exposed ancient fore-arcs in the world. The pre-Tertiary rocks can be divided into two main units. The LeMay Group (Jurassic-Tertiary) forms the structural basement to Alexander Island and comprises greenschist-facies metasedimentary rocks. It is interpreted as a Mesozoic accretionary prism. The Fossil Bluff Group unconformably overlies and is faulted against the LeMay Group; it represents the sedimentary fill of a coeval fore-arc basin. Subduction ceased due to a series of Cenozoic ridge-trench collisions which began off Alexander Island at 50 Ma and got progressively younger to the north. However, the approach of the ridge can be inferred from the Mesozoic deposits of the Fossil Bluff Group (Jurassic-Cretaceous) in Alexander Island. In this paper, I will show that the ocean floor being subducted became progressively shallower through Jurassic and Cretaceous time (by at least 1,000 m). The result in the forearc basin was a sudden shallowing in water depths from at least 1,000 m at 125 Ma, to emergent at 100 Ma. This forced shallowing ended sedimentation in the basin and resulted in considerable topography on Alexander Island that persists to the present day.

  13. 2012 ARPA-E Energy Innovation Summit Keynote Presentation (Frederick W. Smith, FedEx Corporation), with Introduction by Senator Lamar Alexander (TN)

    ScienceCinema

    Smith, Frederick W. (FedEx Corporation, Chairman, President and CEO)

    2014-04-09

    The third annual ARPA-E Energy Innovation Summit was held in Washington D.C. in February, 2012. The event brought together key players from across the energy ecosystem - researchers, entrepreneurs, investors, corporate executives, and government officials - to share ideas for developing and deploying the next generation of energy technologies. Following introduction by Senator Lamar Alexander of Tennessee, Frederick W. Smith, Chairman, President, and CEO of FedEx Corporation, gave the third keynote presentation of the day.

  14. Using the Alexander Collection to measure the effects of climate change on the grasshoppers of the southern Rocky Mountains of Colorado

    NASA Astrophysics Data System (ADS)

    Nufio, C. R.; Bowers, D. M.; Guralnick, R. P.

    2007-12-01

    The current study utilizes the recently curated and databased Alexander Grasshopper Collection coupled with a new resurvey program to measure the effects of climate change on grasshoppers found along an elevational gradient in the southern Rocky Mountains of Colorado. The Alexander Collection is composed of approximately 19,000 pinned grasshoppers and a series of field data notebooks from a three year 1958-1960 survey project. During these survey years, Alexander processed over 65,000 grasshoppers from repeatedly sampled sites along an elevational gradient from Boulder (1530 m elev.) to Mt Evans (3900m elev.) in the Colorado Front Range. Data from 2006 shows that at mid-elevation sites grasshoppers are becoming adults 15-28 days earlier than they did nearly a half century ago. We found no changes in the time to reach adulthood at the high elevation sites. Preliminary data from 2007 (a year with milder spring temperatures) suggests that unlike the dramatic patterns documented in 2006, that the time to reach adulthood for grasshoppers at low and high elevation sites was not much different than it was 50 years ago. In 2007, several grasshopper species at mid-elevation did become adults earlier than they had a half century ago.

  15. Alexander von Humboldt: galvanism, animal electricity, and self-experimentation part 1: formative years, naturphilosophie, and galvanism.

    PubMed

    Finger, Stanley; Piccolino, Marco; Stahnisch, Frank W

    2013-01-01

    During the 1790s, Alexander von Humboldt (1769-1859), who showed an early interest in many facets of natural philosophy and natural history, delved into the controversial subject of galvanism and animal electricity, hoping to shed light on the basic nature of the nerve force. He was motivated by his broad worldview, the experiments of Luigi Galvani, who favored animal electricity in more than a few specialized fishes, and the thinking of Alessandro Volta, who accepted specialized fish electricity but was not willing to generalize to other animals, thinking Galvani's frog experiments flawed by his use of metals. Differing from many German Naturphilosophen, who shunned "violent" experiments, the newest instruments, and detailed measurement, Humboldt conducted thousands of galvanic experiments on animals and animal parts, as well as many on his own body, some of which caused him great pain. He interpreted his results as supporting some but not all of the claims made by both Galvani and Volta. Notably, because of certain negative findings and phenomenological differences, he remained skeptical about the intrinsic animal force being qualitatively identical to true electricity. Hence, he referred to a "galvanic force," not animal electricity, in his letters and publications, a theoretical position he would abandon with Volta's help early in the new century. PMID:23581538

  16. Genetic Ablation of Nrf2/Antioxidant Response Pathway in Alexander Disease Mice Reduces Hippocampal Gliosis but Does Not Impact Survival

    PubMed Central

    Hagemann, Tracy L.; Jobe, Emily M.; Messing, Albee

    2012-01-01

    In Alexander disease (AxD) the presence of mutant glial fibrillary acidic protein (GFAP), the major intermediate filament of astrocytes, triggers protein aggregation, with marked induction of a stress response mediated by the transcription factor, Nrf2. To clarify the role of Nrf2 in AxD, we have crossed Gfap mutant and transgenic mouse models into an Nrf2 null background. Deletion of Nrf2 eliminates the phase II stress response normally present in mouse models of AxD, but causes no change in body weight or lifespan, even in a severe lethal model. AxD astrocytes without Nrf2 retain features of reactivity, such as expression of the endothelin-B receptor, but have lower Gfap levels, a decrease in p62 protein and reduced iron accumulation, particularly in hippocampus. Microglial activation, indicated by Iba1 expression, is also diminished. Although the Nrf2 response is generally considered beneficial, these results show that in the context of AxD, loss of the antioxidant pathway has no obvious negative effects, while actually decreasing Gfap accumulation and pathology. Given the attention Nrf2 is receiving as a potential therapeutic target in AxD and other neurodegenerative diseases, it will be interesting to see whether induction of Nrf2, beyond the endogenous response, is beneficial or not in these same models. PMID:22693571

  17. Listening to the whispers of matter through Arabic hermeticism: new studies on The Book of the Treasure of Alexander.

    PubMed

    Alfonso-Goldfarb, Ana Maria; Jubran, Safa Abou Chahla

    2008-07-01

    The Jabirian Corpus refers to the K. Thahirat Al-'Iskandar, "The Book of the Treasure of Alexander" (hereafter BTA), as one of several forgeries suggesting that alchemical secrets were hidden in inscriptions in various places. The book was neglected until 1926, when Julius Ruska discussed it in his work on the Emerald Tablet, placing the BTA within the literature related to the development of Arabic alchemy. His preliminary study became an essential reference and encouraged many scholars to work on the BTA in the following decades. Some years ago, we completed the first translation of the BTA into a Western language. The work was based on the acephalous Escorial manuscript, which we identified as a fourteenth-century copy of the BTA. This manuscript is peculiar, as part of it is encoded. After finishing our translation, we started to establish the text of the BTA. At present, the text is in process of fixation--to be followed by textual criticism--and has been the main focus of a thorough study of ours on medieval hermeticism and alchemy. A sample of the work currently in progress is presented in this paper: an analysis of the variations between different manuscripts along with a study and English translation of its alchemical chapter. PMID:19048971

  18. ``The Waters I am Entering No One yet Has Crossed'': Alexander Friedman and the Origins of Modern Cosmology*

    NASA Astrophysics Data System (ADS)

    Belenkiy, A.

    2013-04-01

    Ninety years ago, in 1922, Alexander Friedman (1888-1925) demonstrated for the first time that the General Relativity equations admit non-static solutions and thus the Universe may expand, contract, collapse, and even be born. The fundamental equations he derived still provide the basis for the current cosmological theories of the Big Bang and the Accelerating Universe. Later, in 1924, he was the first to realize that General Relativity allows the Universe to be infinite. Friedman's ideas initially met strong resistance from Einstein, yet from 1931 he became their staunchest supporter. This essay connects Friedman's cosmological ideas with the 1998-2004 results of the astronomical observations that led to the 2011 Nobel Prize in Physics. It also describes Friedman's little known topological ideas of how to check General Relativity in practice and compares his contributions to those of Georges Lemaître. Recently discovered corpus of Friedman's writings in the Ehrenfest Archives at Leiden University sheds some new light on the circumstances surrounding his 1922 work and his relations with Paul Ehrenfest.

  19. Growing community: the impact of the Stephanie Alexander Kitchen Garden Program on the social and learning environment in primary schools.

    PubMed

    Block, Karen; Gibbs, Lisa; Staiger, Petra K; Gold, Lisa; Johnson, Britt; Macfarlane, Susie; Long, Caroline; Townsend, Mardie

    2012-08-01

    This article presents results from a mixed-method evaluation of a structured cooking and gardening program in Australian primary schools, focusing on program impacts on the social and learning environment of the school. In particular, we address the Stephanie Alexander Kitchen Garden Program objective of providing a pleasurable experience that has a positive impact on student engagement, social connections, and confidence within and beyond the school gates. Primary evidence for the research question came from qualitative data collected from students, parents, teachers, volunteers, school principals, and specialist staff through interviews, focus groups, and participant observations. This was supported by analyses of quantitative data on child quality of life, cooperative behaviors, teacher perceptions of the school environment, and school-level educational outcome and absenteeism data. Results showed that some of the program attributes valued most highly by study participants included increased student engagement and confidence, opportunities for experiential and integrated learning, teamwork, building social skills, and connections and links between schools and their communities. In this analysis, quantitative findings failed to support findings from the primary analysis. Limitations as well as benefits of a mixed-methods approach to evaluation of complex community interventions are discussed. PMID:22167317

  20. Geosciences Information for Teachers (GIFT) Workshops held in Conjunction with Alexander von Humboldt (AvH) EGU Conferences.

    NASA Astrophysics Data System (ADS)

    Laj, C. E.; Cifelli, F.

    2014-12-01

    Given the increasing success of the GIFT workshops held in conjunction with the General Assemblies, since 2010 EGU has also developed a series of GIFT workshops held in conjunction with AvH conferences. The Alexander von Humboldt Conference Series of the European Geosciences Union are a series of meetings held outside of Europe, in particular in South America, Africa or Asia, on selected topics of geosciences with a socio-economic impact for regions on these continents, jointly organised with the scientists and their institutes and the institutions of these regions. Associated GIFT workshops were held in Merida, Yucatan, on the theme of Climate Change, Natural Hazards and Societies (March 2010), then in Penang, Malaysia (June 2011) on the theme of Ocean Acidification, in November 2012 in Cusco (Peru) on the theme of Natural Disasters, Global Change and the Preservation of World Heritage Sites, finally in Istanbul (March 2014) on "High Impact Natural Hazards Related to the Euro-Mediterranean Region. The next GIFT workshop is already planned for October 2015 in Adis Ababa (Ethiopia) on the theme "Water". In each case, the GIFT workshop was held on the last two days of the AvH conference and reunited 40-45 teachers from the nation where the AvH was held. Keynote speakers from AvH were speakers to the GIFT workshops which also included hands-on activities animated by sciences educators. In 3 cases of the 4 cases, these GIFT workshops represented the first workshop specifically aimed at teachers held in the country, and therefore represents a significant Earth Sciences contribution to secondary education in non European countries.

  1. Geosciences Information for Teachers (GIFT) Workshops held in Conjunction with Alexander von Humboldt (AvH) EGU Conferences

    NASA Astrophysics Data System (ADS)

    Laj, Carlo; Cifelli, Francesca

    2015-04-01

    The Alexander von Humboldt Conference Series of the European Geosciences Union are a series of meetings held outside of Europe, in particular in South America, Africa or Asia, on selected topics of geosciences with a socio-economic impact for regions on these continents, jointly organised with the scientists and their institutes and the institutions of these regions. Given the increasing success of the GIFT workshops held in conjunction with the General Assemblies, since 2010 EGU has also developed a series of GIFT workshops held in conjunction with AvH conferences. Associated GIFT workshops were held in Merida, Yucatan, on the theme of Climate Change, Natural Hazards and Societies (March 2010), then in Penang, Malaysia (June 2011) on the theme of Ocean Acidification, in November 2012 in Cusco (Peru) on the theme of Natural Disasters, Global Change and the Preservation of World Heritage Sites, finally in Istanbul (March 2014) on "High Impact Natural Hazards Related to the Euro-Mediterranean Region. The next GIFT workshop is already planned for October 2015 in Adis Ababa (Ethiopia) on the theme "Water". In each case, the GIFT workshop was held on the last two days of the AvH conference and reunited 40-45 teachers from the nation where the AvH was held. Keynote speakers from AvH were speakers to the GIFT workshops which also included hands-on activities animated by sciences educators. These GIFT workshops represented the first workshops specifically aimed at teachers held in the country, and therefore represents a significant Earth Sciences contribution to secondary education in non European countries.

  2. Alexander Ya. Orolv - Well-Known Scientist and Recognized Organizer of Astronmoical Research. Little Known Facts of His Life

    NASA Astrophysics Data System (ADS)

    Yatskiv, Ya. S.; Vavilova, I. B.; Korsun', A. A.

    Alexander Ya. Orlov is a well-known astronomer and geophysicist as well as a worldrecognized organizer of scientific research in Russia, the USSR, and Ukraine. Orlov has formulated his main scientific ideas during the Odesa's period of life. He studied a tidal deformation of the Earth and its polar motion using the gravity and latitude observations. He has proposed new defenitions of a mean pole and a mean latitude, as wel as a new method for determing the Earth pole coordinates. To the end of 1940-ties, the Orlov's scientific ideas were implemented and stimulated a development of a research field, which is now called as Astrogeodynamics or Space Geodynamics. Among the representatives of the Orlov's scientific school are about 20 Doctors of Sciences and more than 40 Candidates of Sciences, including the members of Academy of Sciences of Ukraine and other countries. Among them are N.Stoyko-Radilenko (France), J.Witkowski (Poland), V.Zhardetsky (Yugoslavia-Austria-USA), D.Pyaskovsky, Z.Aksent'eva, E.Lavrentieva, N.Popov, E.Fedorov and A.Korol in Ukraine. The deserved followers of the Orlov's scientific ideas were also I.Androsov, I.Dyukov, K.Mansurova, B.Novopashennyj, N.V.Zimmerman in Russia and M.Bursa (Chesh Republic), who worked with him, as well as his sons, A.A.Orlov and B.A. Orlov. The Orlov's life and scientific activity were fully described in many articles. For that reason in this paper we will focus on the little-known facts of the Orlov's scientific-organizational activity, for example, the Orlov's appointments as a director of observatories in Odesa, Poltava, m.Pip-Ivan, Pulkovo, and Kyiv; interesesting facts related to his membership in the Academies of Sciences of the USSR and Ukrainian SSR; organization of a large-scale program on the latitude observations and gravimetric survey. We describe briefly his life and his astrogeodynamic scientific school.

  3. Alexander von Humboldt: galvanism, animal electricity, and self-experimentation part 2: the electric eel, animal electricity, and later years.

    PubMed

    Finger, Stanley; Piccolino, Marco; Stahnisch, Frank W

    2013-01-01

    After extensive experimentation during the 1790s, Alexander von Humboldt remained skeptical about "animal electricity" (and metallic electricity), writing instead about an ill-defined galvanic force. With his worldview and wishing to learn more, he studied electric eels in South America just as the new century began, again using his body as a scientific instrument in many of his experiments. As had been the case in the past and for many of the same reasons, some of his findings with the electric eel (and soon after, Italian torpedoes) seemed to argue against biological electricity. But he no longer used galvanic terminology when describing his electric fish experiments. The fact that he now wrote about animal electricity rather than a different "galvanic" force owed much to Alessandro Volta, who had come forth with his "pile" (battery) for multipling the physical and perceptable effects of otherwise weak electricity in 1800, while Humboldt was deep in South America. Humboldt probably read about and saw voltaic batteries in the United States in 1804, but the time he spent with Volta in 1805 was probably more significant in his conversion from a galvanic to an electrical framework for understanding nerve and muscle physiology. Although he did not continue his animal electricity research program after this time, Humboldt retained his worldview of a unified nature and continued to believe in intrinsic animal electricity. He also served as a patron to some of the most important figures in the new field of electrophysiology (e.g., Hermann Helmholtz and Emil du Bois-Reymond), helping to take the research that he had participated in to the next level. PMID:23581510

  4. The Neotropical tanyderid Araucoderus gloriosus (Alexander) (Diptera, Tanyderidae), with description of the egg, larva and pupa, redescription of adults, and notes on natural history.

    PubMed

    Madriz, R Isaí; Courtney, Gregory W

    2016-01-01

    Larvae, pupae and adults of Araucoderus gloriosus (Alexander) were collected during fieldwork in Chilean Patagonia, December 2013 and January 2014. Eggs were obtained from females that oviposited in captivity. Association of all life stages is based on co-occurrence and rearing of individual larvae to adults. A diagnosis for the genus and species is provided. Descriptions of the egg, larva and pupa and redescriptions of the male and female are completed. Eggs of A. gloriosus are the first described for Tanyderidae. Natural history characteristics for this species, including microhabitat, copulatory behavior and oviposition, are discussed. PMID:27615889

  5. Dislocation-density-based modeling of the plastic behavior of 4H-SiC single crystals using the Alexander-Haasen model

    NASA Astrophysics Data System (ADS)

    Gao, B.; Kakimoto, K.

    2014-01-01

    To dynamically model the plastic deformation of 4H-SiC single crystals during physical vapor transport (PVT) growth, the Alexander-Haasen model, originally proposed for the elemental semiconductor, is extended into IV-IV compound semiconductors. By fitting the model parameters to the experimental data, we show that the Alexander-Haasen model can describe the plastic deformation of 4H-SiC single crystals if the activation of the carbon-core partial dislocation is modeled in the high-temperature region (above 1000 °C) and the silicon-core partial dislocation is modeled in the low-temperature region (below 1000 °C). We then apply the same model to the dynamical deformation process of a 4H-SiC single crystal during PVT growth. The time evolution of the dislocation density is shown, and the effects of the cooling time on the final dislocation density, residual stress and stacking faults are also examined.

  6. Correlation of Emkuckfaw Group metagraywackes with the Wedowee Group, Northern Piedmont, Alabama: Implications for the interpretation of the Alexander City fault

    SciTech Connect

    Bieler, D.B. . Geology Dept.)

    1993-03-01

    Recent field studies to clarify stratigraphic relationships between the Elkahatchee Quartz Diorite Gneiss and the Brevard zone lead to the interpretation that part of the Emuckfaw Group is correlative with, and probably structurally continuous with, part of the Wedowee Group. The Josie Leg formation of Bieler and Deininger (1987) is a sequence of metagraywackes and interbedded metapelites; it is here interpreted as a coarse submarine fan facies. The northwestern contact of the unit, frequently mapped as the Alexander City fault, maps into the Wadley Line in the New Site and Daviston quadrangles. The southeastern contact is a sheared contact with structurally overlying migmatitic rocks that include quartzites and calcsilicates. The Josie Leg and Wedowee rocks form a southwesterly plunging synform in which the Elkahatchee lies. Where the contact between the units is gently dipping it is mapped as the Wadley line. Where the contact has been folded and dips steeply, it is highly sheared and is mapped as the Alexander City fault. It is impossible to determine at this time how much the section has been attenuated during the shearing. Although the contact has been interpreted as structural, the data are not unambiguous. The Josie Leg/Wedowee contact may be a stratigraphic contact with the apparent structural discordance reflecting the different mechanical behavior of the contrasting lithologies.

  7. Late Pleistocene ice-shelf, valley-glacier and ice-sheet interactions on Alexander Island, Antarctic Peninsula: implications for climatic and ice-volume changes

    NASA Astrophysics Data System (ADS)

    Davies, Bethan; Hambrey, Michael; Glasser, Neil; Smellie, John; Carrivick, Jonathan; Bentley, Michael

    2014-05-01

    Recent rapid warming across the Antarctic Peninsula has resulted in ice-sheet thinning, dramatic ice-shelf collapse, acceleration of ice-flow velocities and widespread glacier recession. Reconstructing past rates, volumes and magnitudes of cryospheric change, particularly with respect to the former configuration of ice sheets and ice shelves, and their response to changing oceanic and climatic regimes, is vital in providing a context for this change, in order to improve predictions of future ice-sheet behaviour, and to provide glacio-isostatic adjustment corrections for gravimetric measurements of contemporary ice loss. This research aimed to investigate valley glacier and ice-shelf interactions during the Last Glacial Maximum (LGM) and Holocene Epoch across George VI Sound and Alexander Island, western Antarctic Peninsula, an area with a well-preserved but poorly dated record. We identify four principal stratigraphic units: (1) a high-elevation drift with Alexander Island erratics only (interpreted as recording older advances of ice from the interior of the island), (2) a lower-elevation drift with exotic Palmer Land erratics (interpreted as ice-shelf moraine, representing incursions of George VI Ice Shelf onto Ablation Point Massif), (3) multiple overlapping sequences of valley glacier moraine and ice-shelf moraine, presumed to be Holocene in age, and (4) more recent processes and units, including frozen epishelf lakes, slope processes and alluvial fans. On-going cosmogenic nuclide dating on these sediments (in progress; 25 10Be exposure ages) has the potential to unlock the complex history and interactions of ice streams, valley glaciers and ice shelves in this area. This work will also provide the first long-term record of sea-level indicators, allowing the first estimates of glacial unloading, rates of uplift and ice-sheet thinning to be calculated. The Holocene record of the ice shelf, preserved in the younger ice-shelf moraines and in the overlapping

  8. The question of sign-language and the utility of signs in the instruction of the deaf: two papers by Alexander Graham Bell (1898).

    PubMed

    Bell, Alexander Graham

    2005-01-01

    Alexander Graham Bell is often portrayed as either hero or villain of deaf individuals and the Deaf community. His writings, however, indicate that he was neither, and was not as clearly definite in his beliefs about language as is often supposed. The following two articles, reprinted from The Educator (1898), Vol. V, pp. 3-4 and pp. 38-44, capture Bell's thinking about sign language and its use in the classroom. Contrary to frequent claims, Bell does not demand "oral" training for all deaf children--even if he thinks it is the superior alternative--but does advocate for it for "the semi-deaf" and "the semi-mute." "In regard to the others," he writes, "I am not so sure." Although he clearly voices his support for oral methods and fingerspelling (the Rochester method) over sign language, Bell acknowledges the use and utility of signing in a carefully-crafted discussion that includes both linguistics and educational philosophy. In separating the language used at home from that in school and on the playground, Bell reveals a far more complex view of language learning by deaf children than he is often granted. (M. Marschark). PMID:15778208

  9. A canine orthologue of the human GFAP c.716G>A (p.Arg239His) variant causes Alexander disease in a Labrador retriever.

    PubMed

    Van Poucke, Mario; Martlé, Valentine; Van Brantegem, Leen; Ducatelle, Richard; Van Ham, Luc; Bhatti, Sofie; Peelman, Luc J

    2016-06-01

    Alexander disease (AxD) is a fatal neurodegenerative disorder of astrocyte dysfunction in man, for which already a number of causal variants are described, mostly de novo dominant missense variants in the glial fibrillary acidic protein (GFAP). A similar disorder was already phenotypically described in animals but without the identification of causal variants. We diagnosed a Labrador retriever with a juvenile form of AxD based on clinical (tetraparesis with spastic front limbs mimicking 'swimming puppy syndrome') and pathological (the detection of GFAP containing Rosenthal fibers in astrocytes) features. In order to identify a causal variant, the coding sequences of the four detected GFAP transcript variants (orthologues from human transcript variants α, γ, δ/ɛ and κ) were sequenced. From the five detected variants, a heterozygous c.719G>A nucleotide substitution resulting in a p.Arg240His substitution was considered to be causal, because it is orthologous to the heterozygous de novo dominant c.716G>A (p.Arg239His) hotspot variant in man, proven to cause a severe phenotype. In addition, the variant was not found in 50 unrelated healthy Labrador retrievers. Because the condition in dogs is morphologically similar to man, it could be a promising animal model for further elucidating the genotype/phenotype correlation in order to treat or prevent this disease. PMID:26486469

  10. An autopsied case of adult-onset bulbospinalform Alexander disease with a novel S393R mutation in the GFAP gene.

    PubMed

    Iwasaki, Yasushi; Saito, Yufuko; Mori, Keiko; Ito, Masumi; Mimuro, Maya; Aiba, Ikuko; Saito, Kozo; Mizuta, Ikuko; Yoshida, Tomokatsu; Nakagawa, Masanori; Yoshida, Mari

    2015-01-01

    A 50-year-old Japanese man with no apparent family history noticed diplopia. He gradually showed gait disturbance and dysuria. Abducens disorder of eye movement with nystagmus, tongue atrophy with fasciculation, spastic tetraparesis, and sensory disturbance were also observed. MRI showed severe atrophy of the medulla oblongata to the cervical cord ("tadpole appearance"). Tracheotomy and gastrostomy were performed 7 years after onset due to the development of bulbar palsy. Death occurred following respiratory failure after 11 years total disease duration. The brain weighed 1,380 g. The cerebrum, cerebellum, midbrain, and upper pons were preserved from atrophy, but the medulla oblongata to the cervical cord showed severe atrophy. A few Rosenthal fibers were observed in the cerebral white matter, basal ganglia, and cerebellum, whereas numerous Rosenthal fibers were observed in the medulla oblongata to the cervical cord. Myelin loss with relatively preserved axons was extensively observed from the middle of the pons to the spinal cord. The clinicopathological diagnosis was adult-onset bulbospinal-form Alexander disease. Glial fibrillary acidic protein (GFAP) gene analysis revealed a novel mutation of S393R. Expression patterns of S393R mutant GFAP using adrenal carcinoma-derived cells (SW13 cells) showed a decreased number of filamentous structures and abnormal aggregates. PMID:25828773

  11. Generalized rainbows and unfolded glories of oblate drops: organization for multiple internal reflections and extension of cusps into Alexander's dark band.

    PubMed

    Marston, P L; Kaduchak, G

    1994-07-20

    Oblate drops of water can produce caustics where, unlike a simple Airy caustic, more than two rays merge. We extend previous treatments of generalized primary rainbows based on catastrophe optics [Opt. Lett. 10, 588 (1985); Proc. R. Soc. (London) A 438, 397 (1992)] to rays having (p - 1) = 2 to 5 internal reflections. The analysis is for a horizontally illuminated ellipsoid with a vertical symmetry axis. Aspect ratios causing a vanishing of the vertical curvature at the equator for the outgoing wave front are found from generalized ray tracing. In response to infinitesimal deformation, the axial caustic of real glory rays unfolds producing cusps. Laboratory observations with laser illumination demonstrate that cusps resulting from rays with five internal reflections extend into Alexander's dark band when the drop's aspect ratio is near 1.08. The evolution of this p = 6 scattering pattern as cusps meet the quinary rainbow is suggestive of an E(6) catastrophe. For ellipsoids of varying aspect ratio and refractive index N, there is an organizing singularity associated with an exceptionally flat outgoing wave front from spheres with N = p. PMID:20935841

  12. Observatoriya imeni russkogo astronoma v dalekoj Brazilii. K 100-letiyu so diya rozhdeniya Aleksandra Ivanovicha Postoeva (1900 - 1976) %t An observatory in distant Brazil named after a Russian astronomer (dedicated to Alexander Postoyev (1900 - 1976) centennial anniversary

    NASA Astrophysics Data System (ADS)

    Marques Dos Santos, P.; Matsuura, O. T.

    This is a biographical note on the life of Dr. Alexander Postoyev, a victim of Stalin's purge of Soviet astronomers in 1936 - 1937. Together with his family, he left the Soviet Union in 1943 and lived in Germany as a refugee and a "displaced person" until 1952, when he moved to Brazil. There, he started the second part of his professional career. Thanks to his efforts, the Astronomical and Geophysical Institute (IAG) of the University of Sao Paulo (USP) was for the first time included in programs of international cooperation, thus contributing to the institutional consolidation of IAG/USP as a leading center of astronomical research and teaching in Brazil now.

  13. Evaluating return on investment in a school based health promotion and prevention program: the investment multiplier for the Stephanie Alexander Kitchen Garden National Program.

    PubMed

    Eckermann, Simon; Dawber, James; Yeatman, Heather; Quinsey, Karen; Morris, Darcy

    2014-08-01

    Successful health promotion and disease prevention strategies in complex community settings such as primary schools rely on acceptance and ownership across community networks. Assessing multiplier impacts from investment on related community activity over time are suggested as key alongside evidence of program health effects on targeted groups of individuals in gauging community network engagement and ownership, dynamic impacts, and program long term success and return on investment. An Australian primary school based health promotion and prevention strategy, the Stephanie Alexander Kitchen Garden National Program (SAKGNP), which has been providing garden and kitchen classes for year 3-6 students since 2008, was evaluated between 2011 and 2012. Returns on Australian Federal Government investment for school infrastructure grants up to $60,000 are assessed up to and beyond a two year mutual obligation period with: (i) Impacts on student lifestyle behaviours, food choices and eating habits surveyed across students (n = 491 versus 260) and parents (n = 300 versus 234) in 28 SAKGNP and 14 matched schools, controlling for school and parent level confounders and triangulated with SAKGNP pre-post analysis; (ii) Multiplier impacts of investment on related school and wider community activity up to two years; and (iii) Evidence of continuation and program evolution in schools observed beyond two years. SAKGNP schools showed improved student food choices (p = 0.024) and kitchen lifestyle behaviour (p = 0.019) domains compared to controls and in pre-post analysis where 20.0% (58/290) reported eating fruit and vegetables more often and 18.6% (54/290) preparing food at home more often. No significant differences were found in case control analysis for eating habits or garden lifestyle behaviour domains, although 32.3% of children helped more in the garden (91/278) and 15.6% (45/289) ate meals together more often in pre-post analysis. The multiplier impact on total

  14. Genetics Home Reference: Alexander disease

    MedlinePlus

    ... gene provides instructions for making a protein called glial fibrillary acidic protein. Several molecules of this protein ... lead to the production of a structurally altered glial fibrillary acidic protein. The altered protein is thought ...

  15. Obituary: Alexander Dalgarno (1928 - 2015)

    NASA Astrophysics Data System (ADS)

    Hartquist, Tom; Babb, James F. Babb; Loeb, Avi

    Alex Dalgarno's major contributions to the understanding of fundamental atomic and molecular processes enabled him to develop diagnostics of the physical conditions of atmospheres and astrophysical sources and to elucidate the roles of such processes in controlling those environments. He greatly influenced the research of physicists, chemists, atmospheric scientists, and astronomers, leading Sir David Bates to write, "There is no greater figure than Alex in the history of atomic physics and its applications." Alex was born and grew up in London. As a child, he enjoyed mathematical puzzles and did well at sports. He was invited to try out for the Tottenham Hotspur soccer team, but his professional sporting career ended due to an injury, which did not prevent Alex playing tennis and squash into his ninth decade. In 1945 Alex began to study Mathematics at University College London (UCL). In 1947 Sir Harrie Massey invited him to work for a PhD in Physics and suggested that Alex investigate collisions of metastable helium atoms in helium gas to determine the cross sections for excitation transfer. Richard Buckingham was Alex's immediate supervisor. After completing his graduate study in 1951, Alex became a member of staff in Applied Mathematics at the Queen's University of Belfast (QUB). He served as the Director of the Computational Laboratory after a 1954 visit to MIT, which had an electronic computer, led Alex to persuade colleagues that QUB needed one. In 1957, the poet Philip Larkin was the best man at the marriage of Alex to Barbara Kane. They had four children, Fergus, Penelope, Piers, and Rebecca, but the marriage dissolved after ten years. Alex's important work during the 1950s on the quantitative evaluation of long-range interactions underpinned his collaborations on precise scattering calculations relevant to ultra-cold collisions and the formation of atomic Bose-Einstein condensates over four decades later. He investigated the theory of atomic and molecular collisions and calculated charge transfer cross sections. Some of these proved later to be important for forming the spectra of diffuse astronomical matter surrounding high mass stars and 100 million solar mass black holes at the centers of active galaxies. In the early 1950s David Bates stimulated Alex's interest in the study of quantum processes occurring in the upper terrestrial atmosphere. Together they considered the sources of the nightglow and dayglow features and concluded that the altitudes previously inferred for them from observations were up to several hundred kilometers too large. Experiments carried on V2 rockets, like those seen by Alex in wartime London, proved him and David to be right. Alex felt that though many theorists believe that "physics is embodied in its equations," it is instead "to be found in the solutions to the equations." He was a master at developing and applying methods that simplified calculations leading to reliable solutions. Exploiting the contemporary advances in electronic computation, by the 1960s Alex and his colleagues were able to address atomic and molecular processes of increasing complexity. Their development and early applications of the S-matrix theory of molecular rotational excitation by particle impact triggered major advances in molecular physics and theoretical chemistry and in the understanding of processes important in many environments, including a wide variety of astrophysical sources. In 1967 Alex became a professor in the Harvard Department of Astronomy and a member of the staff of the Smithsonian Astrophysical Observatory. He was a team member for several Atmosphere Explorer satellite missions, which elucidated the roles of atoms and ions in the upper atmosphere and paved the way for further applications to the other planets. By 1969 Alex was publishing papers on molecular hydrogen (H2) radiative processes, including photodissociation, in which the foundations of molecular astrophysics began to emerge. H2 is the most abundant astrophysical molecule and the main constituen

  16. Obituary: Alexander Dalgarno (1928 - 2015)

    NASA Astrophysics Data System (ADS)

    Hartquist, Tom; Babb, James F. Babb; Loeb, Avi

    Alex Dalgarno's major contributions to the understanding of fundamental atomic and molecular processes enabled him to develop diagnostics of the physical conditions of atmospheres and astrophysical sources and to elucidate the roles of such processes in controlling those environments. He greatly influenced the research of physicists, chemists, atmospheric scientists, and astronomers, leading Sir David Bates to write, "There is no greater figure than Alex in the history of atomic physics and its applications." Alex was born and grew up in London. As a child, he enjoyed mathematical puzzles and did well at sports. He was invited to try out for the Tottenham Hotspur soccer team, but his professional sporting career ended due to an injury, which did not prevent Alex playing tennis and squash into his ninth decade. In 1945 Alex began to study Mathematics at University College London (UCL). In 1947 Sir Harrie Massey invited him to work for a PhD in Physics and suggested that Alex investigate collisions of metastable helium atoms in helium gas to determine the cross sections for excitation transfer. Richard Buckingham was Alex's immediate supervisor. After completing his graduate study in 1951, Alex became a member of staff in Applied Mathematics at the Queen's University of Belfast (QUB). He served as the Director of the Computational Laboratory after a 1954 visit to MIT, which had an electronic computer, led Alex to persuade colleagues that QUB needed one. In 1957, the poet Philip Larkin was the best man at the marriage of Alex to Barbara Kane. They had four children, Fergus, Penelope, Piers, and Rebecca, but the marriage dissolved after ten years. Alex's important work during the 1950s on the quantitative evaluation of long-range interactions underpinned his collaborations on precise scattering calculations relevant to ultra-cold collisions and the formation of atomic Bose-Einstein condensates over four decades later. He investigated the theory of atomic and molecular collisions and calculated charge transfer cross sections. Some of these proved later to be important for forming the spectra of diffuse astronomical matter surrounding high mass stars and 100 million solar mass black holes at the centers of active galaxies. In the early 1950s David Bates stimulated Alex's interest in the study of quantum processes occurring in the upper terrestrial atmosphere. Together they considered the sources of the nightglow and dayglow features and concluded that the altitudes previously inferred for them from observations were up to several hundred kilometers too large. Experiments carried on V2 rockets, like those seen by Alex in wartime London, proved him and David to be right. Alex felt that though many theorists believe that "physics is embodied in its equations," it is instead "to be found in the solutions to the equations." He was a master at developing and applying methods that simplified calculations leading to reliable solutions. Exploiting the contemporary advances in electronic computation, by the 1960s Alex and his colleagues were able to address atomic and molecular processes of increasing complexity. Their development and early applications of the S-matrix theory of molecular rotational excitation by particle impact triggered major advances in molecular physics and theoretical chemistry and in the understanding of processes important in many environments, including a wide variety of astrophysical sources. In 1967 Alex became a professor in the Harvard Department of Astronomy and a member of the staff of the Smithsonian Astrophysical Observatory. He was a team member for several Atmosphere Explorer satellite missions, which elucidated the roles of atoms and ions in the upper atmosphere and paved the way for further applications to the other planets. By 1969 Alex was publishing papers on molecular hydrogen (H2) radiative processes, including photodissociation, in which the foundations of molecular astrophysics began to emerge. H2 is the most abundant astrophysical molecule and the main constituent of the regions where stars form. Interstellar H2 was first detected directly in the following year, and data for interstellar H2 began to become abundant in 1973. Alex was well prepared and led efforts to interpret these data, from which he was able to infer the physical properties of diffuse interstellar molecular clouds. At nearly the same time he was involved in work on the ionization and energy deposition in H2 by nearly relativistic and relativistic particles called cosmic rays. The work has relevance to emission in the atmospheres of the giant planets, as well as for conditions in interstellar molecular clouds. Cosmic ray induced ionization initiates much of the basic chemistry in star forming regions, and the emissions of the product molecules control the temperatures and allow the diagnosis of the physical conditions and dynamics of the stellar nurseries. For more than four decades Alex elucidated the chemical networks governing the molecular abundances in a wide variety of astrophysical sources including star forming regions, supernova ejecta, the pregalactic universe, and extreme environments like those in the vicinities of X-ray sources powered by accretion onto black holes. The refinement of the models led to calculations predicting the existence of subsequently discovered negative ions in giant molecular clouds. One of his astrophysical interests that intrigued him late in his career was the emission of soft X-rays by comets and in the heliosphere due to charge transfer with solar wind particles, and he also worked on related processes occurring in the atmospheres of the giant planets. Alex remained very active in fundamental atomic and molecular physics, as well as for its applications to astrophysics and to terrestrial and extraterrestrial planetary atmospheres. Ultra-cold collisions and ultra-cold chemistry were major interests for Alex for much of the latest phase of his career, most recently with pioneering work on atom-molecule collisions. In the early 1980s Alex had concerns about the future of atomic, molecular, and optical (AMO) physics in the United States, where it was inadequately funded and somewhat out of fashion in many of the physics departments providing most of the physicists who became university faculty. Alex played a key role in efforts to address this issue and led a proposal to the National Science Foundation that resulted in the founding on 1 November 1988 of the Institute of Theoretical Atomic and Molecular Physics (ITAMP) at the Harvard-Smithsonian Center for Astrophysics. Alex served for five years as the first ITAMP director. A number of the former ITAMP students and postdoctoral researchers have become leading AMO physicists, and its visitor program and workshops have led to the identification and stimulation of the leading areas of AMO physics. Alex was a Fellow of the Royal Society, a member of the National Academy of Sciences, and a member (Honorary) of the Royal Irish Academy. He received many medals, including the Benjamin Franklin Medal in Physics, the Royal Society's Hughes Medal, the Royal Astronomical Society's Gold Medal, the American Geophysical Society's Fleming Medal, and the Royal Society of Chemistry's Spiers Medal. He served as the editor of the Astrophysical Journal Letters for nearly thirty years starting in 1973, as the Chair of the Harvard Department of Astronomy from 1971 to 1976, and as the Acting Director of Harvard College Observatory and then the Acting Director of the Harvard-Smithsonian Center for Astrophysics from 1971 to 1973 during a critical period of its existence. Alex was a gifted mentor who spoke and wrote with pride of his former students and postdoctoral researchers. He was able to match projects very well with the abilities of the students. He made availability to students a special priority, and despite his supply of problems would encourage students as they developed their own. Alex was very supportive of junior scientists as they developed their careers, and in addition to writing many letters of recommendation he made many visits to colleagues as they were establishing themselves elsewhere. Furthermore, Alex very graciously hosted a number of his former students when they visited. He combined quiet modesty with a confidence that reassured others, and his humor was dry, interactive, and friendly. Alex passed away peacefully on 9 April 2015 in Cambridge, Massachusetts in the company of Fern Creelan, who was his partner for 30 years.

  17. 27 CFR 9.53 - Alexander Valley.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., California. From the beginning point at the northeast corner of Section 32, Township 12 North (T. 12 N... degrees, E. 2,800 feet in a straight line to the northeasterly tip of a small lake; (13) Then N. 57...) Then S. 16 degrees, E. 1,800 feet in a straight line to the point on a peak identified as having...

  18. 27 CFR 9.53 - Alexander Valley.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...) Then east-southeasterly 2,400 feet in a straight line to the top of a peak identified as Chalk Hill; (30) Then south from said peak, in a straight line, approximately 0.2 mile to the point where Chalk..., approximately 1.3 miles, along the roadbed of Chalk Hill Road to the point near the confluence of Brooks...

  19. 27 CFR 9.53 - Alexander Valley.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...) Then east-southeasterly 2,400 feet in a straight line to the top of a peak identified as Chalk Hill; (30) Then south from said peak, in a straight line, approximately 0.2 mile to the point where Chalk..., approximately 1.3 miles, along the roadbed of Chalk Hill Road to the point near the confluence of Brooks...

  20. 27 CFR 9.53 - Alexander Valley.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...) Then east-southeasterly 2,400 feet in a straight line to the top of a peak identified as Chalk Hill; (30) Then south from said peak, in a straight line, approximately 0.2 mile to the point where Chalk..., approximately 1.3 miles, along the roadbed of Chalk Hill Road to the point near the confluence of Brooks...

  1. 27 CFR 9.53 - Alexander Valley.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...) Then east-southeasterly 2,400 feet in a straight line to the top of a peak identified as Chalk Hill; (30) Then south from said peak, in a straight line, approximately 0.2 mile to the point where Chalk..., approximately 1.3 miles, along the roadbed of Chalk Hill Road to the point near the confluence of Brooks...

  2. Alexander Graham Bell in Professional Continuing Education

    ERIC Educational Resources Information Center

    Kasworm, Carol; Hampton, Leonard A.

    1976-01-01

    The University of Georgia Center for Continuing Education and the School of Pharmacy developed and presented, as a pilot project, a series of four telelectures at 10 locations throughout the State. Participating pharmacists were receptive to the approach and reported favorable reactions in the evaluation. (LH)

  3. Alexander Hollaender Distinguished Postdoctoral Fellowship Program:

    SciTech Connect

    Not Available

    1987-01-01

    Based on the information provided by the laboratories, ORAU developed and distributed program literature. The program brochure includes a brief program description, eligibility and selection criteria, program benefits and obligations, programs and research areas of OHER, participating laboratories, and other application information. The program description booklet gives more detail on these areas and also includes a biography of Dr. Hollaender and the laboratory descriptions submitted by the participating laboratories. Copies of the brochure and booklet are given in Appendix A. Appendix B includes a listing of promotional activities as well as some examples of program advertisements, press releases, and journal or newspaper articles. Program promotion resulted in the submission of 93 applications during the first cycle of program operation. The 93 applicants received their doctoral degrees from 53 universities in 28 states and from eight universities in six foreign countries. All but three applicants held or expected to receive a PhD degree;two had MDs;one had a DVM degree. The applicants, with more than 40 different academic majors, represent the full range of disciplines in the life, biomedical, and environmental sciences. Appendix C gives detailed information about each applicant.

  4. Humboldt, Alexander von (1769-1859)

    NASA Astrophysics Data System (ADS)

    Murdin, P.

    2000-11-01

    Naturalist, geographer, explorer, born in Tegel Palace, Berlin. The Humboldt current off the west coast of South America is named after him. He named the gegenschein. He set in train an international project organized by GAUSS to study terrestrial magnetism. His major work, Kosmos, based on lectures at Berlin University, endeavoured to provide a comprehensive physical picture of the universe. ...

  5. The Ukrainian geodynamics school of Alexander Ya. Orlov.

    NASA Astrophysics Data System (ADS)

    Yatskiv, Ya. S.

    First of all a short review of the Orlov's biography is given. Afterwards some scietific achievements of A. Orlov in the field of geodynamics are discussed. Particular attention is paid on the definition of the "mean latitude" and the "mean pole of epoch" given by A. Orlov.

  6. Friedmann [Fridman], Aleksandr [Alexander] Aleksandrovich (1888-1925)

    NASA Astrophysics Data System (ADS)

    Murdin, P.

    2000-11-01

    Mathematician, born in St Petersburg, Russia, where he studied and first worked. After exciting war-time and revolutionary experiences he returned to Petrograd (as it had been re-named, before becoming Leningrad and now St Petersburg again) where he taught mathematics and mechanics. Friedmann took up an interest in EINSTEIN's general theory of relativity, and showed in a classic paper `On the cur...

  7. Learning to See the Ball Using the Alexander Technique

    ERIC Educational Resources Information Center

    Gosselin, Gaynelle

    2011-01-01

    This article begins with a personal anecdote from the author, for whom childhood P.E. classes were exercises in frustration and humiliation largely because she could not master the coordination needed to catch, throw, or hit a ball. She could not keep her eye on the ball despite well-meaning instruction from coaches, friends, and family members.…

  8. A Measurement of "g" Using Alexander's Diving Bell

    ERIC Educational Resources Information Center

    Quiroga, M.; Martinez, S.; Otranto, S.

    2010-01-01

    This paper describes a very simple exercise using an inverted test tube pushed straight down into a column of water to determine the free-fall acceleration "g". The exercise employs the ideal gas law and only involves the measurement of the displacement of the bottom of the "diving bell" and the water level inside the tube with respect to the…

  9. The Intellectual Background of Alexander Bain's "Models of Discourse."

    ERIC Educational Resources Information Center

    Harned, Jon

    1985-01-01

    Explores the discourse modes put forth in Bain's nineteenth century college textbook "English Composition and Rhetoric." Discusses his rationale for shifting from the previous belletristic schemes to the forms of description, narration, exposition, persuasion, and poetry. (HTH)

  10. Alexander Nikolaevich Scriabin (1872-1915): Enlightenment or illness?

    PubMed

    Witztum, Eliezer; Lerner, Vladimir

    2016-08-01

    The similarity between psychotic symptoms and aspects of mystical experiences is well known. It has long been recognized that there are similarities between mystical and spiritual and psychotic experiences. The content of an experience alone usually does not determine whether an individual is psychotic. The Russian composer Scriabin (1872-1915) was among the most famous artists of his time. Scriabin infused his music with mysticism, evolving a modernistic idiom through which he created a musical counterpart to the Symbolist literature of that period. In this paper, we discuss the question that arises from perusing Scriabin's life is whether the composer was a mystic genius or whether he suffered from affective psychopathology with psychotic features. PMID:24906401

  11. Cohomology of toric line bundles via simplicial Alexander duality

    NASA Astrophysics Data System (ADS)

    Jow, Shin-Yao

    2011-03-01

    We give a rigorous mathematical proof for the validity of the toric sheaf cohomology algorithm conjectured in the recent paper by Blumenhagen, Jurke, Rahn, and Roschy (arXiv:1003.5217). We actually prove not only the original algorithm but also a speed-up version of it. Our proof is independent from (in fact appeared earlier on the arXiv than) the proof by Roschy and Rahn (arXiv:1006.2392), and has several advantages such as being shorter and cleaner and can also settle the additional conjecture on "Serre duality for Betti numbers" which was raised but unresolved in arXiv:1006.2392.

  12. Postglacial vegetation history of Mitkof Island, Alexander Archipelago, southeastern Alaska

    USGS Publications Warehouse

    Ager, T.A.; Carrara, P.E.; Smith, Jody L.; Anne, V.; Johnson, J.

    2010-01-01

    An AMS radiocarbon-dated pollen record from a peat deposit on Mitkof Island, southeastern Alaska provides a vegetation history spanning ???12,900??cal yr BP to the present. Late Wisconsin glaciers covered the entire island; deglaciation occurred > 15,400??cal yr BP. The earliest known vegetation to develop on the island (???12,900??cal yr BP) was pine woodland (Pinus contorta) with alder (Alnus), sedges (Cyperaceae) and ferns (Polypodiaceae type). By ???12,240??cal yr BP, Sitka spruce (Picea sitchensis) began to colonize the island while pine woodland declined. By ???11,200??cal yr BP, mountain hemlock (Tsuga mertensiana) began to spread across the island. Sitka spruce-mountain hemlock forests dominated the lowland landscapes of the island until ???10,180??cal yr BP, when western hemlock (Tsuga heterophylla) began to colonize, and soon became the dominant tree species. Rising percentages of pine, sedge, and sphagnum after ???7100??cal yr BP may reflect an expansion of peat bog habitats as regional climate began to shift to cooler, wetter conditions. A decline in alders at that time suggests that coastal forests had spread into the island's uplands, replacing large areas of alder thickets. Cedars (Chamaecyparis nootkatensis, Thuja plicata) appeared on Mitkof Island during the late Holocene.

  13. John Alexander Sinton, MD FRS VC (1884-1956).

    PubMed

    Cook, G C

    2016-05-01

    Brigadier John Sinton is the only individual in history to have been both awarded the Victoria Cross and also elected to the Royal Society. He qualified at Belfast and afterwards joined the Indian Medical Service (IMS). Serving before and during the Great War (1914-18), he was first posted to the North-West Frontier province, and afterwards as a captain in the Indian Expeditionary force in Mesopotamia (now Iraq). It was there in 1916 that, shot in both arms during an engagement and under heavy gunfire, he remained steadfastly at his post; for this bravery he received the Victoria Cross. Following the war he carried out major researches into malaria in India, and became Director of the Malaria Survey of India Both there and shortly afterwards, Sinton published about 200 papers on various aspects of malaria and leishmaniasis. In England, he later worked at the London School of Hygiene and Tropical Medicine and the Ministry of Health's laboratory at Horton, Epsom. In 1946, he was elected to the Royal Society for his researches into malaria and kala-azar, and following retirement he underwent another distinguished career in Northern Ireland. PMID:24833542

  14. Vortex modeling for rotor aerodynamics - The 1991 Alexander A. Nikolsky Lecture

    NASA Technical Reports Server (NTRS)

    Gray, Robin B.

    1992-01-01

    The efforts toward realistic vortex modeling for rotary wings which began under the guidance of professor A. A. Nikolsky of Princeton University in 1955-1956 are discussed. Attention is given to Nikolsky's flow-visualization studies and major theoretical considerations for vortex modeling. More recent efforts by other researchers have led to models of increasing complexity. The neglect of compressibility and viscous effects in the classical approach is noted to be a major limiting factor in full-scale rotor applications of the classical vortex theory; it has nevertheless been valuable for the delineation of problem areas and the guiding of both experimental and theoretical investigations.

  15. Alexander Meets Michotte: A Simulation Tool Based on Pattern Programming and Phenomenology

    ERIC Educational Resources Information Center

    Basawapatna, Ashok

    2016-01-01

    Simulation and modeling activities, a key point of computational thinking, are currently not being integrated into the science classroom. This paper describes a new visual programming tool entitled the Simulation Creation Toolkit. The Simulation Creation Toolkit is a high level pattern-based phenomenological approach to bringing rapid simulation…

  16. Review Symposium on "Culture and Pedagogy: International Comparisons in Primary Education," by Robin Alexander.

    ERIC Educational Resources Information Center

    Broadfoot, Patricia; Little, Angela W.

    2003-01-01

    Two reviews of an ambitious comparative study of elementary classroom practices and realities in the United States (Michigan), England, France, Russia, and India. There is no single definition of best practice in education, for both means and ends are culturally specific. Recent English educational policy emphasizing a generic definition and…

  17. 77 FR 35028 - Bill Alexander, M.D.; Decision and Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-12

    ... after closing his medical practice in late 2008, he agreed to transport marijuana for a drug.... Leslie, 68 FR 15227, 15230 (2003). I ``may rely on any one or a combination of factors and may give each.... Medicine Shoppe-Jonesborough, 73 FR 363, 387 (2008). In this matter, I have considered all of the...

  18. Feldenkrais Method, Alexander Technique, and yoga--body awareness therapy in the performing arts.

    PubMed

    Schlinger, Marcy

    2006-11-01

    The three disciplines described are practiced by many individuals for a myriad of reasons. Depending upon ability and depth of study, teachers of all three disciplines may have specific competencies with which to analyse, instruct, and interact with students/clients. In the author's experience, persons who seek out these practices and incorporate them into their daily lives and expressions of physical activity often are motivated to maintain or establish an optimal state of well-being and function. Physicians and therapists who work with performing artists are in a position to encourage such positive direction in patients, provide information on local resources, and consider the practices as collaborative and adjunctive to medical care. PMID:17097486

  19. Conversations with Four Highly Productive Educational Psychologists: Patricia Alexander, Richard Mayer, Dale Schunk, and Barry Zimmerman

    ERIC Educational Resources Information Center

    Patterson-Hazley, Melissa; Kiewra, Kenneth A.

    2013-01-01

    This article seeks to answer the questions: Who are the most productive and influential educational psychologists? What factors characterize these educational psychologists? And, what advice might they pass along to budding scholars? To determine the top educational psychologists, we surveyed the membership of Division 15 (Educational Psychology)…

  20. Collaborating with Alexander Scriabine and the Miles Institute for Preclinical Pharmacology.

    PubMed

    Janis, Ronald A

    2015-11-15

    This article represents a timely opportunity to express my affection, admiration and gratitude to Professor David Triggle. David was my Ph.D. advisor as well as a key consultant in the 1980s and early 1990s for research programs at Miles Institute for Preclinical Pharmacology in West Haven, CT, the U.S. research operation of Bayer AG, in the areas of Ca(2+) and K(+) channel ligands. The binding methodology developed in his laboratory was used to search for an endogenous ligand for L-type Ca(2+) channels. We did not find the substance that we were searching for, a genetically-determined, competitive inhibitor for the 1,4-dihydropyridine binding site, but instead isolated the endogenous ligand for the brain's own marijuana, anandamide. Devane, Mechoulam and coworkers first discovered that this compound was the endogenous ligand for delta-9-tetrahydrocannabinol, the active substance in cannabis. The endogenous endocannabinoid system is now the target of many exciting new approaches to drug discovery. PMID:26119821

  1. 78 FR 53630 - Airworthiness Directives; Alexander Schleicher GmbH & Co. Segelflugzeugbau Sailplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-30

    ... Register on May 23, 2013 (78 FR 30791), and proposed to supersede AD 64-07-05, Amendment 701 (29 FR 3227... opportunity to participate in developing this AD. We received no comments on the NPRM (78 FR 30791, May 23... proposed in the NPRM (78 FR 30791, May 23, 2013) for correcting the unsafe condition; and Do not add...

  2. Alexander Graham Bell Association for the Deaf and Hard of Hearing

    MedlinePlus

    ... Bell! September 29, 2016 The 2016 Legacy of Innovation Gala Visit the new AG Bell Gala website ... deaf children can do! our community Legacy of Innovation Gala Registration Open! Your Letters Evan Mercer provided ...

  3. The Integration of Cambridge: Alexander Crummell as Undergraduate, 1849-1853

    ERIC Educational Resources Information Center

    Stockton, C. R.

    1977-01-01

    "When Crummell went up to Queens' College in 1849, the university had never received so conspicuous a figure. He was almost twice the age of his fellow undergraduates... He had been a popular lecturer to vast audiences throughout Great Britain. He was the author of a well-received publication. He was an American. He was a priest. And most…

  4. Alexander Disease and Megalencephalic Leukoencephalopathy with Subcortical Cysts: Leukodystrophies Arising from Astrocyte Dysfunction

    ERIC Educational Resources Information Center

    Gorospe, J. Rafael; Maletkovic, Jelena

    2006-01-01

    Disorders of white matter are some of the most commonly encountered conditions in the practice of child neurology. For a child presenting with evidence of neurological impairment, a magnetic resonance imaging (MRI) of the brain is usually performed and often proves informative in suggesting the diagnosis. Traditionally, primary white matter…

  5. A Darwinian mystery: fluctuations in runoff from the la Plata basin (Alexander von Humboldt Medal Lecture)

    NASA Astrophysics Data System (ADS)

    Clarke, R. T.

    2012-04-01

    During the voyage of HMS Beagle, Charles Darwin sailed in a small boat along the River Paraná, a major tributary of the la Plata drainage system. He wrote about the occurrence of severe droughts (the latest of which had been termed the "gran seco") alternating with periods of severe flooding. From reports received, he concluded that these events appeared to be cyclic with a period "of about fifteen years". Because extended periods of low flow in Brazilian rivers are of immense economic importance, the presentation describes a search for the material which led Darwin to this conclusion. A prolonged period of low flow in another la Plata tributary - the River Paraguay - not unlike the "gran seco" reported by Darwin, has occurred more recently; if such low flows were to recur in the future, the consequences would be severe for a region where more than 70% of energy is supplied by hydropower. A priori considerations suggest the use of statistical long-memory models for predicting River Paraguay water-levels, and some preliminary results from their use are presented.

  6. Alexander v. Gardner-Denver: A Threat to Title VII Rights

    ERIC Educational Resources Information Center

    Richards, Richard F.

    1975-01-01

    An examination of the decision on the rights of an employee, who has unsuccessfully pursued a race or sex discrimination claim through arbitration, to "relitigate" the claim under Title VII, Civil Rights Act of 1964. Conclusion: the decision endangers Title VII rights by granting too much weight to prior arbitration awards. (JT)

  7. Hydrologic Impacts of Climate Change: Quantification of Uncertainties (Alexander von Humboldt Medal Lecture)

    NASA Astrophysics Data System (ADS)

    Mujumdar, Pradeep P.

    2014-05-01

    Climate change results in regional hydrologic change. The three prominent signals of global climate change, viz., increase in global average temperatures, rise in sea levels and change in precipitation patterns convert into signals of regional hydrologic change in terms of modifications in water availability, evaporative water demand, hydrologic extremes of floods and droughts, water quality, salinity intrusion in coastal aquifers, groundwater recharge and other related phenomena. A major research focus in hydrologic sciences in recent years has been assessment of impacts of climate change at regional scales. An important research issue addressed in this context deals with responses of water fluxes on a catchment scale to the global climatic change. A commonly adopted methodology for assessing the regional hydrologic impacts of climate change is to use the climate projections provided by the General Circulation Models (GCMs) for specified emission scenarios in conjunction with the process-based hydrologic models to generate the corresponding hydrologic projections. The scaling problem arising because of the large spatial scales at which the GCMs operate compared to those required in distributed hydrologic models, and their inability to satisfactorily simulate the variables of interest to hydrology are addressed by downscaling the GCM simulations to hydrologic scales. Projections obtained with this procedure are burdened with a large uncertainty introduced by the choice of GCMs and emission scenarios, small samples of historical data against which the models are calibrated, downscaling methods used and other sources. Development of methodologies to quantify and reduce such uncertainties is a current area of research in hydrology. In this presentation, an overview of recent research carried out by the author's group on assessment of hydrologic impacts of climate change addressing scale issues and quantification of uncertainties is provided. Methodologies developed with conditional random fields, Dempster-Shafer theory, possibility theory, imprecise probabilities and non-stationary extreme value theory are discussed. Specific applications on uncertainty quantification in impacts on streamflows, evaporative water demands, river water quality and urban flooding are presented. A brief discussion on detection and attribution of hydrologic change at river basin scales, contribution of landuse change and likely alterations in return levels of hydrologic extremes is also provided.

  8. Mars-Like Soils in the Atacama Desert, Chile (Alexander von Humboldt Medal lecture)

    NASA Astrophysics Data System (ADS)

    Navarro-Gonzalez, R.

    2009-04-01

    The Viking missions showed the martian soil to be lifeless and depleted in organic material and indicated the presence of one or more reactive oxidants. The presence of Mars-like soils have been documented in the extreme arid region of the Atacama Desert. The Atacama desert is one of the driest and oldest deserts of the world that extends across 1000 km from 30°S to 20°S along the Pacific coast of South America. Geological and soil mineralogical evidence suggest that extreme arid conditions have persisted in this desert for about 10-15 Myrs. The surface soil from this region has organic species only at trace levels and extremely low levels of culturable bacteria. Some samples from the extreme arid region were tested for DNA and none was recovered. Incubation experiments, patterned after the Viking labeled-release experiment but with separate biological and nonbiological isomers, show active decomposition of organic species in these soils by nonbiological processes. The Atacama Desert is now a valuable testing ground by NASA and ESA for instruments and experiments designed for future Mars missions for the search of life.

  9. 78 FR 30791 - Airworthiness Directives; Alexander Schleicher GmbH & Co. Segelflugzeugbau Sailplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-23

    ..., Amendment 701 (29 FR 3227, March 11, 1964). That AD required actions intended to address an unsafe condition on some of the products listed above. Since we issued AD 64-07-05, Amendment 701 (29 FR 3227, March... from AD 64-07-05, Amendment 701 (29 FR 3227, March 11, 1964) for Models Ka2B, Ka 6, Ka 6 B, Ka 6 BR,...

  10. A bold new future for public health or implementing the "Alexander Haig" idea.

    PubMed

    Mahan, C S

    2000-01-01

    An amalgam of effort by public health practitioners and academics is needed to attain the goal of public health taking charge of U.S. health care early in the new millenium. Numerous ideas for joint collaborations in service, research, and teaching are presented. Goals, quality improvement and reporting, customer satisfaction, and leadership training are developing strengths in the field that will help make rapid progress toward the goal. Oversight of health services by public health is essential to the development of a successful U.S. health system. PMID:10724696

  11. Measuring the World: How theory follows observation (Alexander von Humboldt Medal)

    NASA Astrophysics Data System (ADS)

    Savenije, Hubert H. G.

    2015-04-01

    I started my professional career as a hydrologist working for the government of Mozambique. I was responsible for overseeing the hydrological network, the operational hydrology and answering specific questions related to water resources availability and the occurrence of floods. In the late 1970s and early 1980s, the use of telecommunication and computers was still very limited. We had to work with handbooks, lecture notes and consultancy reports, but mostly with our brains. The key to answering a specific question was to go into the field and observe. We measured as much as we could to understand the processes that we observed. I didn't know it at the time, but this perfectly fits in the tradition of Von Humboldt. During my time in Mozambique I surveyed during and after extreme floods, such as the 1984 flood caused by the tropical cyclone Demoina. I surveyed the geometry, hydraulics and salt intrusion of 4 major Mozambican estuaries. And I measured the quality and the quantity of the flows draining onto these estuaries. Having only limited access to the literature, it was a survey without much theoretical guidance. This maybe slowed us down a bit, and sometimes led to inefficient approaches, but scientifically it was a gold mine. Not being biased by established theories is a great advantage. One does not follow onto the well-trodden, but sometimes erroneous, paths of others. After working for 6 years in Mozambique I joined an international consultant, for whom I worked for 6 years in many different countries in Asia, Africa and South America. Although the access to literature and other people's experience was better, I continued the practice of observing before believing. These 12 years of doing hydrology in practice formed the basis for the development of my own theories on hydrological processes, salt intrusion in estuaries, tidal hydraulics and even atmospheric moisture recycling. So when I started on my PhD at the age of 38, I made a completely different start from what has become normal nowadays. It was the first time I really had the opportunity to study the literature and to confront my own theory with the work of others. How different is this from how we guide our PhD students today. In my Von Humboldt lecture I shall give examples of how field observation was crucial in developing new insights and new theories. I shall present highlights of my theories on: salt intrusion and tidal dynamics in estuaries; atmospheric moisture recycling; landscape based hydrological modeling; and the sizing of root zone storage capacity. I shall emphasise the use of analytical approaches and of the need to develop hypotheses and conceptual models based on field experience, observations and perceptions of how nature works.

  12. The controversy between Alexander Friedmann and Albert Einstein about the possibility of a non-static world (German Title: Die Kontroverse zwischen Alexander Friedmann und Albert Einstein um die Möglichkeit einer nichtstatischen Welt)

    NASA Astrophysics Data System (ADS)

    Singer, Georg

    Einstein's treatment of the cosmological problem as well as his unshakeable adherence to his own static solution of the complete field equations was throughout determined by Ernst Mach's idea of relativity of inertia. Friedmann, however, like Eddington, Weyl and others did not consider Mach's principle to be a part of general relativity, and so he regarded a time dependent developing spatial geometry as being consistent with world matter at relative rest. In his final statement to the controversy, Einstein acknowledged just formal correctness of Friedmann's results. Actually his criticism was not due ``to a miscalculation'', as he was ready to admit, but was owed to a fundamental fixed idea which continued to exist and which was the cause of his disavowal of physical significance of dynamical solutions.

  13. Native Agency and the Making of "The North American Indian": Alexander B. Upshaw and Edward S. Curtis

    ERIC Educational Resources Information Center

    Zamir, Shamoon

    2007-01-01

    The twenty volumes of ethnographic text and pictorial photography and the twenty portfolios of large, finely printed photogravures that together comprise "The North American Indian" were the product of an extraordinary labor by Edward S. Curtis, an extensive and shifting team of co-workers, and the participation of hundreds of Native Americans. By…

  14. Alexander Pope and the Comma Splice, or, Contradictions and Problems in College Composition--An Administrator's View.

    ERIC Educational Resources Information Center

    Bataille, Robert R.

    The training of doctoral candidates in English often does not match the kind of teaching they must do upon taking their first jobs: namely, training is in literature, while most jobs are available in composition. Even when acceptable composition teachers are found, keeping them in the face of budgetary restraints and declining enrollments is…

  15. Is research on soil erosion hazard and mitigation in the Global South still needed? (Alexander von Humbold Medal Lecture)

    NASA Astrophysics Data System (ADS)

    Poesen, Jean

    2016-04-01

    Soil erosion represents a geomorphological and geological hazard that may cause environmental damage (land degradation), property damage, loss of livelihoods and services as well as social and economic disruption. Erosion not only lowers the quality of our soils on site, resulting in a drastic reduction of their ecosystem functions that play a vital role in daily life, but causes also significant sediment-related problems off site. To curb soil erosion problems, a range of soil conservation techniques and strategies have been designed and are being applied. Worldwide, ca. 62 000 research papers on soil erosion and 116 000 on soil conservation have been published (Web of Science, Dec. 2015). The number of such papers dealing with the Global South represents less than 20 % of all papers, despite the fact that many regions in this part of the world face significant soil erosion problems, aggravated by a rapidly growing population and major environmental changes. Given the large number of research papers on this topic, one might therefore conclude that we now know almost everything about the various soil erosion processes and rates, their factors and consequences as well as their control so that little new knowledge can still be added to the vast amount of available information. We refute this conclusion by pointing to some major research gaps that still need to be addressed if we want to use our soils in a more sustainable way. More specifically the following topics need more research attention: 1) improved understanding of both natural and anthropogenic soil erosion processes and their interactions, 2) scaling up soil erosion processes and rates in space and time, and 3) innovative techniques and strategies to prevent or reduce erosion rates. This will be illustrated with case studies from the Global South. If future research focuses on these research gaps, we will 1) better understand processes and their interactions operating at a range of spatial and temporal scales, their rates as well as their on-site and off-site impacts, which is crucial for better targeting erosion control measures and which is academically spoken rewarding, and 2) we will also be in a better position to select the most appropriate and effective soil erosion control techniques and strategies which are badly needed for a sustainable use of our soils in the Anthropocene and for the improvement of environmental conditions worldwide.

  16. Qualitative and quantitative behaviour of planetary systems; Proceedings of the 3rd Alexander von Humboldt Colloquium on Celestial Mechanics, Ramsau, Austria, Mar. 29-Apr. 4, 1992

    NASA Astrophysics Data System (ADS)

    Dvorak, R.; Henrard, J.

    1993-06-01

    Topics addressed include planetary theories, the Sitnikov problem, asteroids, resonance, general dynamical systems, and chaos and stability. Particular attention is given to recent progress in the theory and application of symplectic integrators, a computer-aided analysis of the Sitnikov problem, the chaotic behavior of trajectories for the asteroidal resonances, and the resonant motion in the restricted three-body problem. Also discussed are the second order long-period motion of Hyperion, meteorites from the asteroid 6 Hebe, and least squares parameter estimation in chaotic differential equations.

  17. Identifying Unique Ethical Challenges of Indigenous Field-Workers: A Commentary on Alexander and Richman's "Ethical Dilemmas in Evaluations Using Indigenous Research Workers"

    ERIC Educational Resources Information Center

    Smith, Nick L.

    2008-01-01

    In contrast with nonindigenous workers, to what extent do unique ethical problems arise when indigenous field-workers participate in field studies? Three aspects of study design and operation are considered: data integrity issues, risk issues, and protection issues. Although many of the data quality issues that arise with the use of indigenous…

  18. The Potential of Expanded Arbitration in Resolving Title VII Claims in Light of Alexander v. Gardner-Denver and New Equal Employment Opportunity Commission Policy

    ERIC Educational Resources Information Center

    Boyer, Laura G.

    1976-01-01

    Potential Title VII financial liability, not only for lawyer's fees and court costs, but also for back pay awards, should provide the needed stimulus for union and management to accept altered arbitration as a method of resolving employment discrimination claims. Altered arbitration would be an effective way to limit their financial liability.…

  19. Did Alexander Really Ask, "Do I Appear to You to Be a Bastard?": Using Ancient Texts to Improve Pupils' Critical Thinking

    ERIC Educational Resources Information Center

    Baker, Beth; Mastin, Steven

    2012-01-01

    Beth Baker and Steven Mastin make the case for teaching ancient history in the post-14 curriculum. Pointing out the damaging messages that could be conveyed by assuming that ancient history is not worthy of higher-level and demanding study, they also show the opportunities that are missed if pupils do not return to it when they are able to apply…

  20. Chickamauga National Military Park Tour Roads, Gordon's Slough Bridge, At ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Chickamauga National Military Park Tour Roads, Gordon's Slough Bridge, At the confluence of Alexander's Bridge Road and Gordon's Slough, southeast of Alexander's Bridge, Fort Oglethorpe, Catoosa County, GA

  1. Element analysis and calculation of the attenuation coefficients for gold, bronze and water matrixes using MCNP, WinXCom and experimental data

    NASA Astrophysics Data System (ADS)

    Esfandiari, M.; Shirmardi, S. P.; Medhat, M. E.

    2014-06-01

    In this study, element analysis and the mass attenuation coefficient for matrixes of gold, bronze and water with various impurities and the concentrations of heavy metals (Cu, Mn, Pb and Zn) are evaluated and calculated by the MCNP simulation code for photons emitted from Barium-133, Americium-241 and sources with energies between 1 and 100 keV. The MCNP data are compared with the experimental data and WinXCom code simulated results by Medhat. The results showed that the obtained results of bronze and gold matrix are in good agreement with the other methods for energies above 40 and 60 keV, respectively. However for water matrixes with various impurities, there is a good agreement between the three methods MCNP, WinXCom and the experimental one in low and high energies.

  2. Can Philanthropy Fix Our Schools? Appraising Walter Annenberg's $500 Million Gift to Public Education. Case Studies: New York City by Raymond Domanico; Philadelphia by Carol Innerst; Chicago by Alexander Russo.

    ERIC Educational Resources Information Center

    Thomas B. Fordham Foundation, Washington, DC.

    The best-known model for large-scale private giving to foster education reform is Walter Annenberg's $500 million gift to U.S. public education in 1993. The biggest chunk of this money was used to fund challenge grants in the nine largest U.S. cities. The three case studies and commentary in this report evaluate the success of the Annenberg…

  3. North & South Elevations and Bridge Plan Chickamauga National ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    North & South Elevations and Bridge Plan - Chickamauga National Military Park Tour Roads, Gordon's Slough Bridge, At the confluence of Alexander's Bridge Road and Gordon's Slough, southeast of Alexander's Bridge, Fort Oglethorpe, Catoosa County, GA

  4. Site Plan and Transverse Section Chickamauga National Military Park ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Site Plan and Transverse Section - Chickamauga National Military Park Tour Roads, Gordon's Slough Bridge, At the confluence of Alexander's Bridge Road and Gordon's Slough, southeast of Alexander's Bridge, Fort Oglethorpe, Catoosa County, GA

  5. 78 FR 20931 - National Institute of Environmental Health Sciences; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-08

    ..., Rodbell Auditorium, 111 T. W. Alexander Drive, Research Triangle Park, NC 27709. Closed: May 15, 2013, 8... Environmental Health Sciences, Building 101, Rodbell Auditorium, 111 T. W. Alexander Drive, Research...

  6. Parkinson's Disease: Diagnosis and Treatment | NIH MedlinePlus the Magazine

    MedlinePlus

    ... therapies for Parkinson's include massage, yoga, tai chi, hypnosis, acupuncture, and the Alexander technique, which optimizes posture ... therapies for Parkinson's include massage, yoga, tai chi, hypnosis, acupuncture, and the Alexander technique, which optimizes posture ...

  7. K. a. Ter-Martirosyan as i Remember him

    NASA Astrophysics Data System (ADS)

    Smilga, A. V.

    2013-06-01

    Karen Avetovich Ter-Martirosyan was a remarkable physicist, one of the creators of the great ITEP theoretical physics school. He was a teacher of many brilliant theorists. The most known of them are probably three Alexanders: Alexander Polyakov, Alexander Migdal and Alexander Zamolodchikov. He was also one of my teachers and it is an honor and pleasure for me to write these notes...

  8. Rejoinder to Craig A. Cunningham, David Granger, Jane Fowler Morse, Barbara Stengel, and Terri Wilson, "Dewey, Women, and Weirdoes"

    ERIC Educational Resources Information Center

    Fitzgerald, Terry

    2010-01-01

    It is good to see Cunningham et al. including F. Matthias Alexander in their list of positive influences in John Dewey's life. However, I believe Cunningham's essay, "Shared explorations of body-mind: the reciprocal influences of Dewey and F.M. Alexander", falls short in its acknowledgement of Alexander and in one important aspect is incorrect. In…

  9. 78 FR 59042 - National Institute of Environmental Health Sciences; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-25

    ... Environmental Health Sciences, Building 101, Rodbell Auditorium, 111 T. W. Alexander Drive, Research Triangle... Sciences, Building 101, Rodbell Auditorium, 111 T. W. Alexander Drive, Research Triangle Park, NC 27709... Environmental Health Sciences, Building 101, Rodbell Auditorium, 111 T. W. Alexander Drive, Research...

  10. Antocha crane flies from Taiwan (Diptera: Limoniidae: Limoniinae).

    PubMed

    Podenas, Sigitas; Young, Chen W

    2015-01-01

    Taiwanese species of the crane fly subgenus Antocha (Antocha) Osten Sacken, 1860, are reviewed. Antocha (Antocha) taiwanensis, new species, is described and figured. Previously known species, Antocha (A.) bifida Alexander, 1924a and Antocha (A.) styx Alexander, 1930 are redescribed and illustrated. Antocha (A.) javanensis Alexander, 1915 is removed from the list of Taiwanese crane flies. Antocha (A.) gracillima Alexander, 1924b and species close to Antocha (A.) streptocera Alexander, 1949 are listed for the first time in Taiwan. Identification key for all Taiwanese Antocha species is given. PMID:26624765

  11. Southeastern Alaska tectonostratigraphic terranes revisited

    SciTech Connect

    Brew, D.A.; Ford, A.B.

    1985-04-01

    The presence of only three major tectonostratigraphic terranes (TSTs) in southeastern Alaska and northwestern British Columbia (Chugach, Wrangell, and Alexander) is indicated by critical analysis of available age, stratigraphic, and structural data. A possible fourth TST (Stikine) is probably an equivalent of part or all of the Alexander. The Yakutat block belongs to the Chugach TST, and both are closely linked to the Wrangell and Alexander(-Stikine) TSTs; the Gravina TST is an overlap assemblage. THe Alexander(-Stikine) TSTs is subdivided on the basis of age and facies. The subterranes within it share common substrates and represent large-scale facies changes in a long-lived island-arc environment. The Taku TSTs is the metamorphic equivalent of the upper part (Permian and Upper Triassic) of the Alexander(-Stikine) TSTs with some fossil evidence preserved that indicates the age of protoliths. Similarly, the Tracy Arm TST is the metamorphic equivalent of (1) the lower (Ordovician to Carboniferous) Alexander TST without any such fossil evidence and (2) the upper (Permian to Triassic) Alexander(-Stikine) with some newly discovered fossil evidence. Evidence for the ages of juxtaposition of the TSTs is limited. The Chugach TST deformed against the Wrangell and Alexander TSTs in late Cretaceous. Gravina rocks were deformed at the time and also earlier. The Wrangell TST was stitched to the Alexander(-Stikine) by middle Cretaceous plutons but may have arrived before its Late Jurassic plutons were emplaced. The Alexander(-Stikine) and Cache Creek TSTs were juxtaposed before Late Triassic.

  12. Five new species of Geranomyia Haliday, 1833 (Diptera, Limoniidae) from China.

    PubMed

    Zhang, Xiao; Zhang, Zehua; Yang, Ding

    2016-01-01

    The following five new species of the genus Geranomyia from China are described and illustrated: G. baisensis sp. nov., G. degenerata sp. nov., G. longispina sp. nov., G. maculata sp. nov. and G. nigra sp. nov.. Three known species, G. apicifasciata (Alexander, 1930), G. radialis (Alexander, 1930) and G. sparsiguttata (Alexander, 1937), are listed with new distribution data. A key to the species of the genus Geranomyia from China is presented. PMID:27615830

  13. Site Plan & Transverse Section Chickamauga National Military Park ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Site Plan & Transverse Section - Chickamauga National Military Park Tour Roads, Alexander's Bridge, At the confluence of West Chickamauga Creek and Gordon's Slough, Fort Oglethorpe, Catoosa County, GA

  14. Expedition 35/36 Crew Departs Star City

    NASA Video Gallery

    Expedition 35 Flight Enginners Chris Cassidy, Pavel Vinogradov and Alexander Misurkin participated in traditional ceremonies at the Gagarin Cosmonaut Training Center in Star City, Russia outside Mo...

  15. Expedition 36 Crew Profile

    NASA Video Gallery

    Learn more about Expedition 36 Commander Pavel Vinogradov and Flight Engineers Chris Cassidy, Alexander Misurkin, Karen Nyberg, Fyodor Yurchikhin and Luca Parmitano and their mission aboard the Int...

  16. Can strain magnetize light?

    NASA Astrophysics Data System (ADS)

    2013-02-01

    Strain in photonic structures can induce pseudomagnetic fields and Landau levels. Nature Photonics spoke to Mordechai Segev, Mikael Rechtsman, Alexander Szameit and Julia Zeuner about their unique approach.

  17. Physiological and toxicological transcriptome changes in HepG2 cells exposed to copper Address for reprint requests and other correspondence: J. H. Freedman, Laboratory of Molecular Toxicology, National Institute of Environmental Health Sciences, Mail Drop E1-05, PO Box 12233, 111 T.W. Alexander Dr., Research Triangle Park, NC 27709 (e-mail: freedma1@niehs.nih.gov).

    PubMed Central

    Song, Min Ok; Li, Jianying; Freedman, Jonathan H.

    2009-01-01

    Copper is an essential trace element; however, at supraphysiological levels, it can be extremely toxic. Microarray data from HepG2 cells exposed to 100, 200, 400, and 600 μM copper for 4, 8, 12 and 24 h were generated and analyzed. Principal components, K-means, and hierarchical clustering, interactome, and pathway mapping analyses indicated that these exposure conditions induce physiological and toxicological changes in the HepG2 transcriptome. As a general trend, when the level of toxicity increases, the number and diversity of affected genes, Gene Ontology categories, regulatory pathways, and complexity of interactomes increase. Physiological responses to copper include transition metal ion binding and responses to stress/stimulus, whereas toxicological responses include apoptosis, morphogenesis, and negative regulation of biomolecule metabolism. The global gene expression profile was overlaid onto biomolecular interaction networks and signal transduction cascades using pathway mapping and interactome identification. This analysis indicated that copper modulates signal transduction pathways associated with MAPK, NF-κB, death receptor, IGF-I, hypoxia, IL-10, IL-2, IL-6, EGF, Toll-like receptor, protein ubiquitination, xenobiotic metabolism, leukocyte extravasation, complement and coagulation, and sonic hedgehog signaling. These results provide insights into the global and molecular mechanisms regulating the physiological and toxicological responses to metal exposure. PMID:19549813

  18. Results and Recommendations from the 2009 National Surveys of Randomly Selected and Highly Successful Middle Level Schools

    ERIC Educational Resources Information Center

    McEwin, C. Kenneth; Greene, Melanie W.

    2010-01-01

    While a number of studies have yielded useful information regarding the status of middle level schools in the United States, four linked national surveys provide a longitudinal perspective on the degree of implementation of key middle grades programs and practices. These studies were conducted in 1968 (Alexander, 1968), 1988 (Alexander & McEwin,…

  19. New species of subgenus Tipula (Sivatipula) from China, with redescription of T. (S.) parvauricula and a key to all known species of the Oriental Region (Diptera, Tipulidae, Tipula)

    PubMed Central

    Xue, Guo-Xi; Men, Qiu-Lei

    2016-01-01

    Abstract Species of Tipula (Sivatipula) biprocessa sp. n. from Guangxi, China is described and illustrated as new in the subgenus Tipula (Sivatipula) Alexander, 1964. Tipula (Sivatipula) parvauricula Alexander, 1941 is redescribed and illustrated based on additional morphological characters. Semen pump of this subgenus is discussed. A key to all described species in this group is compiled. PMID:27047238

  20. 1. COPY OF A LATE 19TH CENTURY BUSINESS CARD FOR ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. COPY OF A LATE 19TH CENTURY BUSINESS CARD FOR A. ALEXANDER & SON FLOURING MILLS. CARD OWNED BY THOMAS R. WILSON. Photographer: Berni Rich, Score Photographers, September 1986. - Alexander's Grist Mill, Lock 37 on Ohio & Erie Canal, South of Cleveland, Valley View, Cuyahoga County, OH

  1. Author! Author! A Wonderful, Marvelous, So Good, Very Incredible Author: Judith Viorst

    ERIC Educational Resources Information Center

    Brodie, Carolyn S.

    2005-01-01

    This article presents a brief biography of Judith Viorst, best known for her children's picture books and poetry. Viorst's well-known and most unforgettable character Alexander was based on her youngest son. Alexander was featured by name in the title of three of Viorst's picture books. In fact, Viorst often has used her family life to provide…

  2. New species of subgenus Tipula (Sivatipula) from China, with redescription of T. (S.) parvauricula and a key to all known species of the Oriental Region (Diptera, Tipulidae, Tipula).

    PubMed

    Xue, Guo-Xi; Men, Qiu-Lei

    2016-01-01

    Species of Tipula (Sivatipula) biprocessa sp. n. from Guangxi, China is described and illustrated as new in the subgenus Tipula (Sivatipula) Alexander, 1964. Tipula (Sivatipula) parvauricula Alexander, 1941 is redescribed and illustrated based on additional morphological characters. Semen pump of this subgenus is discussed. A key to all described species in this group is compiled. PMID:27047238

  3. Prompting Students to Contemplate Effective Communication with a Visible Speech Chart from the 1870s

    ERIC Educational Resources Information Center

    Potter, Lee Ann

    2014-01-01

    In this article, director of Educational Outreach at the Library of Congress Lee Ann Potter describes a classroom activity that focuses on an 1876 single-page circular published in Salem, Massachusetts about Alexander Melville Bell's Visible Speech. A. M. Bell's son, Alexander Graham Bell described "Visible Speech" as "a…

  4. Teacher Candidates' Epistemological Beliefs, Dispositions, and Views on Teaching as Persuasion

    ERIC Educational Resources Information Center

    Sinatra, Gale M.; Kardash, CarolAnne M.

    2004-01-01

    Alexander and her colleagues proposed "teaching as persuasion" as a guiding metaphor for conceptual change pedagogy (Alexander, Fives, Buehl, & Mulhern, 2002). However, there is reason to suspect that the term persuasion can have negative connotations for some individuals ( Dole & Sinatra, 1999; Murphy, 2001). Therefore, we examined 182 primarily…

  5. Education Law Texts Usage: Survey Results.

    ERIC Educational Resources Information Center

    Sullivan, Kathleen A.; Zirkel, Perry A.

    1998-01-01

    Identifies the textbooks professors use in education law courses, based on a survey of 110 members of the Education Law Association during 1996-97. Almost half preferred Alexander and Alexander's "American School Law," with McCarthy and Caqmbron-McCabe's "Public School Law" a close second. Only 44% required or suggested additional nontextbook…

  6. Vengeance without Justice, Injustice without Retribution: The Afro-American Council's Struggle against Racial Violence

    ERIC Educational Resources Information Center

    Alexander, Shawn Leigh

    2007-01-01

    On January 19, 1901, just one week after Leavenworth, Kansas, witnessed the burning of Fred Alexander, a twenty-two-year-old black Spanish-American war veteran, the "Wichita Searchlight" called for armed self-defense. The brutal murder of Alexander horrified many African Americans throughout the region, who decided that it was time to stand up and…

  7. Systems Science

    ERIC Educational Resources Information Center

    Christakis, Alexander; Hammond, Debora; Jackson, Michael; Laszlo, Alexander; Mitroff, Ian; Snowden, Dave; Troncale, Len; Carr-Chellman, Alison; Spector, J. Michael; Wilson, Brent

    2013-01-01

    Scholars representing the field of systems science were asked to identify what they considered to be the most exciting and imaginative work currently being done in their field, as well as how that work might change our understanding. The scholars included Alexander Christakis, Debora Hammond, Michael Jackson, Alexander Laszlo, Ian Mitroff, Dave…

  8. 77 FR 18252 - National Institute of Environmental Health Sciences; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-27

    ... Environmental Health Sciences, Building 101, Rodbell Auditorium, 111 T. W. Alexander Drive, Research Triangle... Health Sciences, 615 Davis Dr., KEY615/3112, Research Triangle Park, NC 27709, (919) 541-4980, collman..., Rodbell Auditorium, 111 T.W. Alexander Drive, Research Triangle Park, NC 27709. Open: May 23, 2012, 8:30...

  9. 77 FR 60448 - National Institute of Environmental Health Sciences Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-03

    ... Environmental Health Sciences, Building 101, Rodbell Auditorium, 111 T. W. Alexander Drive, Research Triangle... Environmental Health Sciences, 111 T.W. Alexander Drive, Suite 101, A214, Research Triangle Park, NC 27709. Any... Suites, 2515 Meridian Parkway, Research Triangle Park, NC 27713. Open: November 5, 2012, 8:30 a.m. to...

  10. 75 FR 49500 - National Institute of Environmental Health Sciences; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-13

    ... Environmental Health Sciences, Building 101, Rodbell Auditorium, 111 T. W. Alexander Drive, Research Triangle Park, NC 27709. Contact Person: Gwen W. Collman, PhD, Interim Director, Division of Extramural Research..., Rodbell Auditorium, 111 T. W. Alexander Drive, Research Triangle Park, NC 27709. Closed: September 2,...