Science.gov

Sample records for modification proposal evaluation

  1. Evaluation of proposed panel closure modifications at WIPP

    SciTech Connect

    Allen, Lawrence E.; Silva, Matthew K.; Channell, James K.; Abel, John F.; Morgan, Dudley R.

    2001-12-31

    A key component in the design of the WIPP repository is the installation of concrete structures as panel seals in the intake and exhaust drifts after a panel has been filled with waste containers. As noted in the EPA final rule, the panel seal closure system is intended to block brine flow between the waste panels at the WIPP. On April 17, 2001, the DOE proposed seven modifications to the EPA concerning the design of the panel closure system. EPA approval of these modifications is necessary since the details of the panel design are specified in EPA’s final rule as a condition for WIPP certification. However, the EPA has not determined whether a rulemaking would be required for these proposed design modifications. On September 4, 2001, the DOE withdrew the request, noting that it would be resubmitted on a future date. The Environmental Evaluation Group (EEG) contracted with two engineers, Dr. John Abel and Dr. Rusty Morgan, to evaluate the proposed modifications. The EEG has accepted the conclusions and recommendations from these two experts: 1) replacement of Salado Mass Concrete with a generic salt-based concrete; 2) replacement of the explosion wall with a construction wall; 3) replacement of freshwater grouting with salt-based grouting; 4) option to allow surface or underground mixing; and 5) option to allow up to one year for completion of closure. The proposed modification to allow local carbonate river rock as aggregate is acceptable pending demonstration that no problems will exist in the resulting concrete. The proposed modification to give the contractor discretion in removal of steel forms is not supported. Instead, several recommendations are made to specifically reduce the number of forms left, thereby reducing potential migration pathways.

  2. Manufacturer evaluations of endograft modifications.

    PubMed

    Waninger, Matthew S; Whirley, Robert G; Smith, Louis J; Wolf, Ben S

    2013-03-01

    The motivation to modify the design of a vascular device can arise from a number of sources. Clinical experience with the unmodified device could suggest new design modifications to improve device performance or clinical outcomes. Similarly, clinical success with a device often suggests modifications that could broaden the applicability of the device to enable treatment of different or more advanced disease states. As a specific example, both of these scenarios have arisen during the last decade in the evolution of endovascular grafts for the treatment of abdominal aortic aneurysms, with modifications enabling the treatment of patients with shorter infrarenal necks, more angulated anatomy, and smaller access vessels. These modifications have been made by manufacturers and additionally by physicians who create branched and fenestrated devices. The experience to date with the use of fenestrated devices and the development of chimney, snorkel, and periscope techniques suggests that modifications to off-the-shelf devices may provide some clinical benefit. This experience provides additional motivation for manufacturers to develop devices to address the clinical needs not met with their current product lines. For manufacturers, the device development process includes an assessment of the new device design to determine the appropriate evaluation strategy to support the safety and effectiveness of the modified device. This report provides a high-level overview of the process generally followed by device manufacturers to evaluate a proposed device modification before market release, in accordance with local country regulations and recognized international standards such as the International Organization of Standardization (ISO) standards for endovascular grafts (ISO 25539 Part 1). PMID:23446123

  3. Proposed Modification to the Plutonium Systemic Model.

    PubMed

    Konzen, Kevin; Miller, Scott; Brey, Richard

    2015-10-01

    The currently accepted biokinetic model for plutonium distribution within the human body was recommended by the International Commission on Radiological Protection in publication 67. This model was developed from human and animal studies and behavioral knowledge acquired from other known bone-seeking radionuclides. The biokinetic model provides a mathematical means of predicting the distribution, retention, and clearance of plutonium within the human body that may be used in deriving organ, tissue, and whole body dose. This work proposed a modification to the ICRP 67 systemic model for plutonium that incorporated the latest knowledge acquired from recent human injection studies with physiologically based improvements. In summary, the changes included a separation of the liver compartments, removed the intermediate soft tissue-to-bladder pathway, and added pathways from the blood compartment to both the cortical and trabecular bone volumes. The proposed model provided improved predictions for several bioassay indicators compared to the ICRP 67 model while also maintaining its basic structure. Additionally, the proposed model incorporated physiologically based improvements for the liver and skeleton and continued to ensure efficient coupling with intake biokinetic models. PMID:26313589

  4. Electric utility engineer`s FGD manual -- Volume 2: Major mechanical equipment; FGD proposal evaluations; Use of FGDPRISM in FGD system modification, proposal, evaluation, and design; FGD system case study. Final report

    SciTech Connect

    1996-03-04

    Part 2 of this manual provides the electric utility engineer with detailed technical information on some of the major mechanical equipment used in the FGD system. The objectives of Part 2 are the following: to provide the electric utility engineer with information on equipment that may be unfamiliar to him, including ball mills, vacuum filters, and mist eliminators; and to identify the unique technique considerations imposed by an FGD system on more familiar electric utility equipment such as fans, gas dampers, piping, valves, and pumps. Part 3 provides an overview of the recommended procedures for evaluating proposals received from FGD system vendors. The objectives are to provide procedures for evaluating the technical aspects of proposals, and to provide procedures for determining the total costs of proposals considering both initial capital costs and annual operating and maintenance costs. The primary objective of Part 4 of this manual is to provide the utility engineer who has a special interest in the capabilities of FGDPRISM [Flue Gas Desulfurization PRocess Integration and Simulation Model] with more detailed discussions of its uses, requirements, and limitations. Part 5 is a case study in using this manual in the preparation of a purchase specification and in the evaluation of proposals received from vendors. The objectives are to demonstrate how the information contained in Parts 1 and 2 can be used to improve the technical content of an FGD system purchase specification; to demonstrate how the techniques presented in Part 3 can be used to evaluate proposals received in response to the purchase specification; and to illustrate how the FGDPRISM computer program can be used to establish design parameters for the specification and evaluate vendor designs.

  5. Technical evaluation report (Revision 1) on the proposed design modifications and technical specification changes on grid voltage degradation for the Peach Bottom Atomic Power Station, Units 2 and 3

    SciTech Connect

    Selan, J.C.

    1983-03-11

    This report is a revision of the technical evaluation documented in a separate report dated November 3, 1981 (UCID-19115) on the proposed design modification and Technical Specification changes for the protection of the Class 1E equipment from grid voltage degradation for the Peach Bottom Atomic Power Station, Units 2 and 3. The review criteria are based on several IEEE standards and The Code of Federal Regulations. The evaluation compares the submittals made by the plant with the NRC staff positions and the review criteria. The evaluation finds that the proposed design modifications and the required changes to the Technical Specifications will ensure that the Class 1E equipment will be protected from sustained voltage degradation.

  6. Technical evaluation of the proposed design modifications and technical specification changes on grid voltage degradation (Part A) for the Rancho Seco Nuclear Generating Plant

    SciTech Connect

    White, R.L.

    1980-10-01

    The Rancho Seco Nuclear Generating Plant has two 4160-volt and two 480-volt Class 1E buses. The existing undervoltage protection design uses a single undervoltage relay on each 4160-volt Class 1E bus. If the voltage drops below 3534 volts (85% of 4160 volts), the undervoltage relay will energize a set of load-shedding relays. The load-shedding relays initiate the disconnection of the emergency 4160-volt buses from the off-site source, load shed the emergency 4160-volt buses, start the emergency diesel generators, and provide an enabling signal for the load-sequencing timing circuit. When the emergency diesel generator reaches the required voltage it is connected to the emergency buses and load-sequencing will begin automatically, if a safety injection (SI) signal exists. The licensee has proposed a design change to establish an automatic degraded voltage protection circuitry. The modification consists of incorporating the existing undervoltage protection scheme will consist of 3 undervoltage relays monitoring each 4160-volt emergency bus. The 3 undervoltage relays will be arranged in a 2-out-of-3 coincident logic with a setpoint of 3771 volts +- 38 volts (90.6% of 4160 volts) with a time delay of 12 seconds +- 1.2 seconds.

  7. Project Proposals Evaluation

    NASA Astrophysics Data System (ADS)

    Encheva, Sylvia; Tumin, Sharil

    2009-08-01

    Collaboration among various firms has been traditionally used trough single project joint ventures for bonding purposes. Eventhough the performed work is usually beneficial to some extend to all participants, the type of collaboration option to be adapted is strongly influenced by overall purposes and goals that can be achieved. In order to facilitate a choice of collaboration option best suited to a firm's need a computer based model is proposed.

  8. Modified Kriging: evaluation, modification, and recommendations

    SciTech Connect

    Schultz, C.A.; Myers, S.C.

    1997-09-01

    This report describes modifications to a technique developed by Sandia National Laboratory (SNL) to predict general corrections (traveltime, etc.) for a geographic grid only sparsely covered by calibration points (Hipp and Young, 1997). SNL has worked to create a modified version of linear prediction (kriging) based on the idea of blending the surface back to zero at some distance from the points or, in other words, by damping the solution through the damping of the input data points. LLNL has been working with SNL to evaluate Modified Kriging. This report documents our evaluation of the technique and our resulting recommendations to SNL.

  9. 78 FR 59345 - Proposed Information Collection Request; Comment Request; Modification of Secondary Treatment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-26

    ... AGENCY Proposed Information Collection Request; Comment Request; Modification of Secondary Treatment... request (ICR), ``Modification of Secondary Treatment Requirements for Discharges into Marine Waters... 301(h) program involves collecting information from two sources: (1) The municipal...

  10. Major Modification Determination Process Utilized for Proposed Idaho National Laboratory Projects

    SciTech Connect

    Michael A. Lehto, Ph.D.; Boyd D. Christensen

    2008-05-01

    Over the past three years, several new projects with the potential for major modifications to existing facilities have been considered for implementation at the Idaho National Laboratory (INL). These projects were designated to take place in existing nuclear facilities with existing documented safety analyses. 10 CFR 830.206 requires the contractor for a major modification to a Hazard Category 1, 2, or 3 nuclear facility to obtain Department of Energy (DOE) approval for the nuclear facility design criteria to be used for preparation of a preliminary documented safety analysis (PDSA), as well as creation and approval of the PDSA, before the contractor can procure materials or components or begin construction on the project. Given the significant effort and expense of preparation and approval of a PDSA, a major modification determination for new projects is warranted to determine if the rigorous requirements of a major modification are actually required. Furthermore, performing a major modification determination helps to ensure that important safety aspects of a project are appropriately considered prior to modification construction or equipment procurement. The projects considered for major modification status at the INL included: treatment and packaging of unirradiated, sodium-bonded highly enriched uranium (HEU) fuel and miscellaneous casting scrap in the Materials and Fuels Complex (MFC) Fuel Manufacturing Facility (FMF); post irradiation examination of Advance Fuel Cycle Initiative (AFCI) fuel in the MFC Analytical Laboratory (AL); the Advanced Test Reactor (ATR) gas test loop (GTL); and the hydraulic shuttle irradiation system (HSIS) at ATR. The major modification determinations for three of the proposed projects resulted in a negative major modification. On the other hand, the major modification determination for the GTL project concluded that the project would require a major modification. This paper discusses the process, methods, and considerations used by

  11. Zone III flexor tendon injuries - A proposed modification to rehabilitation.

    PubMed

    Chinchalkar, Shrikant J; Pipicelli, Joey G; Agur, Anne; Athwal, George S

    2015-01-01

    In this manuscript, these authors have utilized years of clinical experience to suggest rehabilitation modifications for Zone III flexor tendon injuries. - VictoriaPriganc, PhD, OTR, CHT, CLT, Practice Forum Editor. PMID:26089286

  12. 48 CFR 2415.305 - Proposal evaluation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... TEP. (3) Technical evaluation. The TEP shall rate each proposal based on the evaluation factors... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Proposal evaluation. 2415... Proposal evaluation. (a) After receipt of proposals, the Contracting Officer will forward copies of...

  13. 48 CFR 1315.305 - Proposal evaluation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Proposal evaluation. 1315... AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Source Selection 1315.305 Proposal evaluation. At the... evaluation team....

  14. 48 CFR 2015.305 - Proposal evaluation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Proposal evaluation. 2015... Proposal evaluation. The contracting officer may provide offerors' cost proposals and supporting financial information to members of the Source Evaluation Panel at the same time technical proposals are distributed...

  15. 75 FR 13049 - Proposed Modification of Class B Airspace; Charlotte, NC

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-18

    ..., SW., Washington, DC 20591; telephone: (202) 267-8783. Correction In proposed rule FR Doc. 2010-4377... Federal Aviation Administration 14 CFR Part 71 RIN 2120-AA66 Proposed Modification of Class B Airspace... the Federal Register of March 3, 2010, regarding the modification of Class B airspace, Charlotte,...

  16. 48 CFR 15.305 - Proposal evaluation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Proposal evaluation. 15.305 Section 15.305 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Source Selection 15.305 Proposal evaluation. (a) Proposal evaluation is an assessment of...

  17. 48 CFR 2415.305 - Proposal evaluation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... technical portion of each proposal to the TEP Chairperson or his or her designee. The cost/price portion of each proposal shall be retained by the Contracting Officer pending initial technical evaluation by the TEP. (3) Technical evaluation. The TEP shall rate each proposal based on the evaluation...

  18. 48 CFR 2415.305 - Proposal evaluation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... technical portion of each proposal to the TEP Chairperson or his or her designee. The cost/price portion of each proposal shall be retained by the Contracting Officer pending initial technical evaluation by the TEP. (3) Technical evaluation. The TEP shall rate each proposal based on the evaluation...

  19. 48 CFR 5215.608 - Proposal evaluation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Proposal evaluation. 5215.608 Section 5215.608 Federal Acquisition Regulations System DEPARTMENT OF THE NAVY ACQUISITION REGULATIONS CONTRACTING BY NEGOTIATION Source Selection 5215.608 Proposal evaluation. (a) When a cost realism evaluation will be performed in...

  20. 48 CFR 715.305 - Proposal evaluation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Proposal evaluation. 715... CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Source Selection 715.305 Proposal evaluation... Performance System to evaluate past performance. (Access to the system by USAID contracting office...

  1. 75 FR 14630 - Proposed Modification of Consent Decree Under the Comprehensive Environmental Response...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-26

    ... Proposed Modification of Consent Decree Under the Comprehensive Environmental Response, Compensation, and... Environmental Protection Agency (``EPA'') $225,000 a year for each of the five years following the modification... Chief, Environmental Enforcement Section, Environment and Natural Resources Division. BILLING CODE...

  2. 48 CFR 215.305 - Proposal evaluation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ....305 Proposal evaluation. (a)(2) Past performance evaluation. When a past performance evaluation is... Business Concerns, the evaluation factors shall include the past performance of offerors in complying with requirements of that clause. When a past performance evaluation is required by FAR 15.304, and the...

  3. Some Proposed Modifications to the 1996 California Probabilistic Hazard Model

    NASA Astrophysics Data System (ADS)

    Cao, T.; Bryant, W. A.; Rowshandel, B.; Toppozada, T.; Reichle, M. S.; Petersen, M. D.; Frankel, A. D.

    2001-12-01

    The California Department of Conservation, Division of Mines and Geology and U. S. Geological Survey are working on the revision of the 1996 California Probabilistic hazard model. Since the release of this hazard model some of the new seismological and geological studies and observations in this area have provided the basis for the revision. Important considerations of model modifications include the following: 1. using a new bilinear fault area-magnitude relation to replace the Wells and Coppersmith (1994) relation for M greater than and equal to 7.0; 2. using the Gaussian function to replace the Dirac Delta function for characteristic magnitude; 3. updating the earthquake catalog with the new M greater than and equal to 5.5 catalog from 1800 to 1999 by Toppozada et al. (2000) and the Berkeley and Caltech catalogs for 1996-2001; 4. balancing the moment release for some major A type faults; 5. adding Abrahamson and Silva attention relation with new hanging wall term; 6. considering different ratios between characteristic and Gutenberg-Richter magnitude-frequency distributions other than 50 percent and 50 percent; 7. using Monte Carlo method to sample the logic tree to produce uncertainty map of coefficient of variation (COV); 8. separating background seismicity in the vicinity of faults from other areas for different smoothing process or no smoothing at all, especially for the creeping section of the San Andreas fault and the Brawley seismic zone; 9. using near-fault variability of attenuation relations to mimic directivity; 10. modifying slip-rates for the Concord-Green Valley, Sierra Madre, and Raymond faults, adding or modifying blind thrust faults mainly in the Los Angeles Basin. These possible changes were selected with input received during several workshops that included participation of geologists and seismologists familiar with the area of concern. With the above revisions and other changes, we expect that the new model should not differ greatly from the

  4. 76 FR 18723 - Proposed Information Collection; Comment Request; Weather Modification Activities Reports

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-05

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE National Oceanic and Atmospheric Administration Proposed Information Collection; Comment Request; Weather... requires that persons who engage in weather modification activities (e.g., cloud seeding) provide...

  5. 48 CFR 1515.305 - Proposal evaluation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Proposal evaluation. 1515.305 Section 1515.305 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY... evaluation....

  6. 48 CFR 915.305 - Proposal evaluation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., approval and nondisclosure procedures as required by 48 CFR (DEAR) 915.207-70 shall be followed and a... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Proposal evaluation. 915... AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Source Selection 915.305 Proposal evaluation....

  7. 48 CFR 1415.305 - Proposal evaluation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Proposal evaluation. 1415.305 Section 1415.305 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Source Selection 1415.305 Proposal evaluation....

  8. 48 CFR 515.305 - Proposal evaluation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... extent authorized by, and in accordance with, the procedures in 48 CFR 515.305-71. ... proposal abstract: (1) This proposal must be used and disclosed for evaluation purposes only. (2) You must apply a copy of this Government notice to any reproduction or abstract of this proposal. (3) You...

  9. 48 CFR 52.214-23 - Late submissions, modifications, revisions, and withdrawals of technical proposals under two-step...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., modifications, revisions, and withdrawals of technical proposals under two-step sealed bidding. 52.214-23... Late submissions, modifications, revisions, and withdrawals of technical proposals under two-step..., Modifications, Revisions, and Withdrawals of Technical Proposals Under Two-Step Sealed Bidding (NOV 1999)...

  10. Evaluation of materials and design modifications for aircraft brakes

    NASA Technical Reports Server (NTRS)

    Ho, T. L.; Kennedy, F. E.; Peterson, M. B.

    1975-01-01

    A test program is described which was carried out to evaluate several proposed design modifications and several high-temperature friction materials for use in aircraft disk brakes. The evaluation program was carried out on a specially built test apparatus utilizing a disk brake and wheel half from a small het aircraft. The apparatus enabled control of brake pressure, velocity, and braking time. Tests were run under both constant and variable velocity conditions and covered a kinetic energy range similar to that encountered in aircraft brake service. The results of the design evaluation program showed that some improvement in brake performance can be realized by making design changes in the components of the brake containing friction material. The materials evaluation showed that two friction materials show potential for use in aircraft disk brakes. One of the materials is a nickel-based sintered composite, while the other is a molybdenum-based material. Both materials show much lower wear rates than conventional copper-based materials and are better able to withstand the high temperatures encountered during braking. Additional materials improvement is necessary since both materials show a significant negative slope of the friction-velocity curve at low velocities.

  11. 48 CFR 715.305 - Proposal evaluation.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Officer and placed in the official file to support the decision to reject all proposals and to cancel the... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Proposal evaluation. 715.305 Section 715.305 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL...

  12. 48 CFR 715.305 - Proposal evaluation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Officer and placed in the official file to support the decision to reject all proposals and to cancel the... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Proposal evaluation. 715.305 Section 715.305 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL...

  13. 48 CFR 715.305 - Proposal evaluation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Officer and placed in the official file to support the decision to reject all proposals and to cancel the... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Proposal evaluation. 715.305 Section 715.305 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL...

  14. 48 CFR 1515.305 - Proposal evaluation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Proposal evaluation. 1515.305 Section 1515.305 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Source Selection 1515.305 Proposal...

  15. 48 CFR 1515.305 - Proposal evaluation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Proposal evaluation. 1515.305 Section 1515.305 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Source Selection 1515.305 Proposal...

  16. 48 CFR 315.305 - Proposal evaluation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...) Cost or price evaluation. (i) The Contracting Officer shall evaluate proposals in accordance with the FAR 15.404. The extent of cost or price analysis in each case depends on the availability of... types, and for cost-reimbursement and time and materials contracts, cost analysis may be required....

  17. 78 FR 33772 - Proposed Modification of Class E Airspace; Brigham City, UT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-05

    ... Executive Order 12866; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR...: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389... Federal Aviation Administration 14 CFR Part 71 Proposed Modification of Class E Airspace; Brigham City,...

  18. 48 CFR 1815.208 - Submission, modification, revision, and withdrawal of proposals. (NASA supplements paragraph (b))

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Submission, modification, revision, and withdrawal of proposals. (NASA supplements paragraph (b)) 1815.208 Section 1815.208 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE ADMINISTRATION CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY...

  19. 76 FR 489 - Proposed Modification of the Minneapolis, MN, Class B Airspace Area; Public Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-05

    ... Federal Aviation Administration 14 CFR Part 71 Proposed Modification of the Minneapolis, MN, Class B... Minneapolis, MN. The purpose of these meetings is to provide interested parties an opportunity to present...), 6040 28th Avenue, South, Minneapolis, MN 55450. (2) The meeting on Saturday, March 19, 2011, will...

  20. 48 CFR 1815.208 - Submission, modification, revision, and withdrawal of proposals. (NASA supplements paragraph (b))

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Submission, modification, revision, and withdrawal of proposals. (NASA supplements paragraph (b)) 1815.208 Section 1815.208 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE ADMINISTRATION CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY...

  1. 77 FR 43183 - Proposed Modification of Class E Airspace; Wolf Point, MT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-24

    ... Executive Order 12866; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR... read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959...-ANM-17 Proposed Modification of Class E Airspace; Wolf Point, MT AGENCY: Federal...

  2. 76 FR 56356 - Proposed Modification of Class E Airspace; Driggs, ID

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-13

    ... Executive Order 12866; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR... 71 continues to read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR... Federal Aviation Administration 14 CFR Part 71 Proposed Modification of Class E Airspace; Driggs,...

  3. 78 FR 5471 - Availability of Draft Environmental Assessment for the Proposed Modification of the Bayonne...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-25

    ...This notice extends the public comment period on a Draft Environmental Assessment (Draft EA) which examines the reasonably foreseeable environmental impacts and socio-economic impacts of the proposed modification of the historic Bayonne Bridge across the Kill Van Kull between Bayonne, New Jersey and Staten Island, New York. This notice also announces a third public meeting, in Newark, NJ, on......

  4. 45 CFR 162.940 - Exceptions from standards to permit testing of proposed modifications.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 1 2013-10-01 2013-10-01 false Exceptions from standards to permit testing of proposed modifications. 162.940 Section 162.940 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES.... (vii) Be technologically independent of the computer platforms and transmission protocols used...

  5. 45 CFR 162.940 - Exceptions from standards to permit testing of proposed modifications.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Exceptions from standards to permit testing of proposed modifications. 162.940 Section 162.940 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES.... (vii) Be technologically independent of the computer platforms and transmission protocols used...

  6. 45 CFR 162.940 - Exceptions from standards to permit testing of proposed modifications.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 1 2012-10-01 2012-10-01 false Exceptions from standards to permit testing of proposed modifications. 162.940 Section 162.940 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES.... (vii) Be technologically independent of the computer platforms and transmission protocols used...

  7. 75 FR 5703 - Proposed Modification of Jet Route J-3; Spokane, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-04

    ... and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of a regulatory.... 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 2. The... Federal Aviation Administration 14 CFR Part 71 Proposed Modification of Jet Route J-3; Spokane, WA...

  8. 78 FR 70900 - Proposed Modification of Area Navigation (RNAV) Route Q-20, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-27

    ... ``significant rule'' under Department of Transportation (DOT) Regulatory Policies and Procedures (44 FR 11034... continues to read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3... Federal Aviation Administration 14 CFR Part 71 RIN 2120-AA66 Proposed Modification of Area...

  9. ESF GROUND SUPPORT - PROPOSED JACKING BRACKET EVALUATION

    SciTech Connect

    Marvin D. Stine

    1996-03-28

    This calculation applies to the Constructor's design of the proposed jacking bracket for the W6 x 20 steel set. The specific features of the jacking bracket evaluated in this analysis are the shear on the bracket bolts, and the effects of the applied moment on the W6 x 20 steel set beam segment.

  10. The Evaluation of Litter Behavior Modification in a River Environment.

    ERIC Educational Resources Information Center

    Wagstaff, Mark C.; Wilson, Beth E.

    1988-01-01

    Behavior modification techniques were evaluated by observing litter collection behavior of commercial rafting groups. The number of litter pieces retrieved by treatment and control groups was significantly different. Results support the idea that verbal appeal and role modeling can be effective litter control techniques. (Author/CW)

  11. Silica aerogel threshold Cherenkov counters for the JLab Hall A spectrometers: improvements and proposed modifications

    SciTech Connect

    Luigi Lagamba; Evaristo Cisbani; S. Colilli; R. Crateri; R. De Leo; Salvatore Frullani; Franco Garibaldi; F. Giuliani; M. Gricia; Mauro Iodice; Riccardo Iommi; A. Leone; M. Lucentini; A. Mostarda; E. Nappi; Roberto Perrino; L. Pierangeli; F. Santavenere; Guido M. Urciuoli

    2001-10-01

    Recently approved experiments at Jefferson Lab Hall A require a clean kaon identification in a large electron, pion, and proton background environment. To this end, improved performance is required of the silica aerogel threshold Cherenkov counters installed in the focal plane of the two Hall A spectrometers. In this paper we propose two strategies to improve the performance of the Cherenkov counters which presently use a hydrophilic aerogel radiator, and convey Cherenkov photons towards the photomultipliers by means of mirrors with a parabolic shape in one direction and flat in the other. The first strategy is aerogel baking. In the second strategy we propose a modification of the counter geometry by replacing the mirrors with a planar diffusing surface and by displacing in a different way the photomultipliers. Tests at CERN with a 5GeV/c multiparticle beam revealed that both the strategies are able to increase significantly the number of the detected Cherenkov photons and, therefore, the detector performance.

  12. 77 FR 64126 - Notice of Proposed Withdrawal of Public Land for the Buffalo Bill Dam and Reservoir Modification...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-18

    ... Bureau of Land Management Notice of Proposed Withdrawal of Public Land for the Buffalo Bill Dam and... recreational facilities constructed in connection with the Buffalo Bill Dam and Reservoir Modification Project... recreation site in the Buffalo Bill Dam and Reservoir Modification Project area: Sixth Principal Meridian...

  13. Proposed modifications to the Lower Mokelumne River Project, California: FERC Project No. 2916-004. Final environmental impact statement

    SciTech Connect

    Not Available

    1993-11-01

    This final environmental impact statement (FEIS) has been prepared for the Federal Energy Regulatory Commission (Commission) to consider modifications to the existing Lower Mokelumne River Project (LMRP) (FERC Project No. 2916-004) in California. Chinook salmon and steelhead trout populations in the lower Mokelumne River have experienced recent declines and fish kills associated, in part, with discharges from Camanche Dam. The California Department of Fish and Game and the California Sportfishing Protection Alliance have asked the Commission to investigate and correct these problems. A wide range of different mitigation actions has been proposed by parties participating in the scoping of this proceeding, and staff has evaluated these proposed actions in this assessment. The staff is recommending a combination of flow and non-flow modifications to the existing license, including new minimum flow and minimum pool elevation requirements at Camanche Reservoir, ramping rates on dam releases, interim attraction and out-migrant spike flows, instream habitat improvements, and a series of studies and monitoring to determine feasible means for solving off-site fish passage problems.

  14. 78 FR 38362 - Notice of Lodging of Proposed Modification to Consent Decree Under the Clean Air Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-26

    ... proposed Modification to the Consent Decree upon written request and payment of reproduction costs. Please... 20044-7611. Please enclose a check or money order for $0.75 (25 cents per page reproduction...

  15. Environmental Assessment for the proposed modification and continued operation of the DIII-D facility

    SciTech Connect

    1995-07-01

    The EA evaluates the proposed action of modifying the DIII-D fusion facility and conducting related research activities at the GA San Diego site over 1995-1999 under DOE contract number DE-ACO3-89ER51114. The proposed action is need to advance magnetic fusion research for future generation fusion devices such as ITER and TPX. It was determined that the proposed action is not a major action significantly affecting the quality of the human environment according to NEPA; therefore a finding of no significant impact is made and an environmental impact statement is not required.

  16. Oxyresveratrol: Structural Modification and Evaluation of Biological Activities.

    PubMed

    Chatsumpun, Nutputsorn; Chuanasa, Taksina; Sritularak, Boonchoo; Lipipun, Vimolmas; Jongbunprasert, Vichien; Ruchirawat, Somsak; Ploypradith, Poonsakdi; Likhitwitayawuid, Kittisak

    2016-01-01

    Oxyresveratrol (2,4,3',5'-tetrahydroxystilbene, 1), a phytoalexin present in large amounts in the heartwood of Artocarpus lacucha Buch.-Ham., has been reported to possess a wide variety of biological activities. As part of our continuing studies on the structural modification of oxyresveratrol, a library of twenty-six compounds was prepared via O-alkylation, aromatic halogenation, and electrophilic aromatic substitution. The two aromatic rings of the stilbene system of 1 can be chemically modulated by exploiting different protecting groups. Such a strategy allows for selective and exclusive modifications on either ring A or ring B. All compounds were evaluated in vitro for a panel of biological activities, including free radical scavenging activity, DNA protective properties, antiherpetic activity, inhibition of α-glucosidase and neuraminidase, and cytotoxicity against some cancer cell lines. Several derivatives were comparably active or even more potent than the parent oxyresveratrol and/or the appropriate positive controls. The partially etherified analogs 5'-hydroxy-2,3',4-trimethoxystilbene and 3',5'-dihydroxy-2,4-dimethoxystilbene demonstrated promising anti-herpetic and DNA protective activities, offering new leads for neuropreventive agent research, whereas 5'-hydroxy-2,3',4,-triisopropoxystilbene displayed anti-α-glucosidase effects, providing a new lead molecule for anti-diabetic drug development. 3',5'-Diacetoxy-2,4-diisopropoxystilbene showed potent and selective cytotoxicity against HeLa cancer cells, but the compound still needs further in vivo investigation to verify its anticancer potential. PMID:27104505

  17. 76 FR 37034 - Proposed Modification of the Las Vegas, NV, Class B Airspace Area; Public Meetings; Correction

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-24

    ... of June 17, 2011, in FR Doc. 2011-15107, on page 35371, column 3, correct meeting number (2) in the... Federal Aviation Administration 14 CFR Part 71 Proposed Modification of the Las Vegas, NV, Class B... of June 17, 2011, concerning a proposal to modify Class B airspace at Las Vegas, NV. The...

  18. A Proposal: Modification for Instruments and Tools Used in the Science Laboratory Setting for Students with Disabilities

    ERIC Educational Resources Information Center

    Kogan, Denis

    2015-01-01

    The purpose of this action research proposal is to create a Modification of Instruments and Tools in Science (MITS) program to address the need for providing Students With Disabilities (SWDs) appropriate access to scientific tools and techniques of scientific inquiry. This proposal contains a review of literature on SWDs, differentiating…

  19. 75 FR 73983 - Proposed Modification of the Salt Lake City, UT, Class B Airspace Area; Public Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-30

    ... Federal Aviation Administration 14 CFR Part 71 Proposed Modification of the Salt Lake City, UT, Class B... information from airspace users and others concerning a proposal to revise the Class B airspace area at Salt... Terminal, 397 North 2370 West, Salt Lake City, UT 84116. (3) The meeting on Thursday, February 3,...

  20. 48 CFR 915.305 - Proposal evaluation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...) Personnel from DOE, other Government agencies, consultants, and contractors, including those who manage or... contractors who operate or manage Government-owned facilities, are to be used as evaluators or...

  1. 48 CFR 915.305 - Proposal evaluation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...) Personnel from DOE, other Government agencies, consultants, and contractors, including those who manage or... contractors who operate or manage Government-owned facilities, are to be used as evaluators or...

  2. 48 CFR 915.305 - Proposal evaluation.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...) Personnel from DOE, other Government agencies, consultants, and contractors, including those who manage or... contractors who operate or manage Government-owned facilities, are to be used as evaluators or...

  3. 23 CFR Appendix D to Subpart A of... - Guidance Criteria for Evaluating Requests for Modifications to the National Highway System

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Modifications to the National Highway System D Appendix D to Subpart A of Part 470 Highways FEDERAL HIGHWAY.... 470, Subpt. A, App. D Appendix D to Subpart A of Part 470—Guidance Criteria for Evaluating Requests.... Proposed additions should connect at each end with other routes on the NHS or serve a major...

  4. A Proposal for Evaluating Cognition in Assertiveness

    ERIC Educational Resources Information Center

    Vagos, Paula; Pereira, Anabela

    2010-01-01

    This article presents the development process and initial psychometric features of an instrument for evaluating cognition in assertiveness. This is an essential social skill for adolescent development and seems to encompass emotional, behavioral, and cognitive aspects. The instrument was created by combining both empirical and theoretical methods…

  5. 48 CFR 252.236-7000 - Modification proposals-price breakdown.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...-price breakdown. 252.236-7000 Section 252.236-7000 Federal Acquisition Regulations System DEFENSE... CLAUSES Text of Provisions And Clauses 252.236-7000 Modification proposals—price breakdown. As prescribed in 236.570(a), use the following clause: Modification Proposals—Price Breakdown (DEC 1991) (a)...

  6. 48 CFR 252.236-7000 - Modification proposals-price breakdown.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...-price breakdown. 252.236-7000 Section 252.236-7000 Federal Acquisition Regulations System DEFENSE... CLAUSES Text of Provisions And Clauses 252.236-7000 Modification proposals—price breakdown. As prescribed in 236.570(a), use the following clause: Modification Proposals—Price Breakdown (DEC 1991) (a)...

  7. 48 CFR 252.236-7000 - Modification proposals-price breakdown.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...-price breakdown. 252.236-7000 Section 252.236-7000 Federal Acquisition Regulations System DEFENSE... CLAUSES Text of Provisions And Clauses 252.236-7000 Modification proposals—price breakdown. As prescribed in 236.570(a), use the following clause: Modification Proposals—Price Breakdown (DEC 1991) (a)...

  8. 48 CFR 252.236-7000 - Modification proposals-price breakdown.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...-price breakdown. 252.236-7000 Section 252.236-7000 Federal Acquisition Regulations System DEFENSE... CLAUSES Text of Provisions And Clauses 252.236-7000 Modification proposals—price breakdown. As prescribed in 236.570(a), use the following clause: Modification Proposals—Price Breakdown (DEC 1991) (a)...

  9. 77 FR 39470 - Proposed Information Collection; Comment Request; Modification to Gulf of Maine/Georges Bank...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-03

    ...; Modification to Gulf of Maine/Georges Bank Herring Letter of Authorization AGENCY: National Oceanic and... modifications to the requirements for midwater trawl vessels issued an All Areas Limited Access Herring Permit and/or an Areas 2 and 3 Limited Access Herring Permit that fish in Northeast (NE) multispecies...

  10. Effects of proposed highway embankment modifications on water-surface elevations in the lower Pearl River flood plain near Slidell, Louisiana

    USGS Publications Warehouse

    Gilbert, J.J.; Schuck-Kolben, R. E.

    1987-01-01

    Major flooding in the lower Pearl River basin in recent years has caused extensive damage to homes and highways in the area. In 1980 and 1983, Interstate Highway 10 and U.S. Highway 190 were overtopped. In 1983, the Interstate Highway 10 crossing was seriously damaged by the flood. The U.S. Geological Survey, in cooperation with the Louisiana Department of Transportation and Development, Office of Highways, used a two-dimensional finite-element surface-water flow model to evaluate the effects the proposed embankment modifications at Interstate Highway 10 and U.S. Highway 90 on the water-surface elevations in the lower Pearl River flood plain near Slidell, Louisiana. The proposed modifications that were considered for the 1983 flood are: (1) Removal of all highway embankments, the natural condition, (2) extension of the West Pearl River bridge by 1,000 feet at U.S. Highway 90, (3) construction of a new 250-foot bridge opening in the U.S. Highways 190 and 90, west of the intersection of the highways. The proposed highway bridge modifications also incorporated lowering of ground-surface elevations under the new bridges to sea level. The modification that provided the largest reduction in backwater, about 35 percent, was a new bridge in Interstate Highway 10. The modification of the West Pearl River bridge at U.S. Highway 90 and replacement of the bridge in U.S. Highway 190 provide about a 25% reduction in backwater each. For the other modification conditions that required structural modifications, maximum backwater computed on the west side of the flood plain ranges from 0.0 to 0.8 foot and on the east side from 0.0 to 0.6 foot. Results show that although backwater is greater on the west side of the flood plain than on the east side, upstream of highway embankments, backwater decreases more rapidly in the upstream direction on the west side of the flood plain than on the east side. Analysis of the proposed modifications indicates that backwater would still occur on

  11. 78 FR 15739 - Notice of Lodging of Proposed Third Modification to Consent Decree Under the Clean Air Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-12

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF JUSTICE Notice of Lodging of Proposed Third Modification to Consent Decree Under the Clean Air Act On February 22... Unit 4); (5) to the installation of 200 MW of renewable energy; (6) to provide the State...

  12. 76 FR 79140 - Proposed Modification of VOR Federal Airways V-135 and V-137; Southwest United States

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-21

    ...'' under Department of Transportation (DOT) Regulatory Policies and Procedures (44 FR 11034; February 26... read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959... Federal Aviation Administration 14 CFR Part 71 RIN 2120-AA66 Proposed Modification of VOR Federal...

  13. 78 FR 18271 - Proposed Modification of VOR Federal Airway V-345 in the Vicinity of Ashland, WI

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-26

    ... Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of a... read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959... Federal Aviation Administration 14 CFR Part 71 RIN 2120-AA66 Proposed Modification of VOR Federal Airway...

  14. 77 FR 54860 - Proposed Modification of VOR Federal Airway V-170 in the Vicinity of Devils Lake, ND

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-06

    ...'' under Department of Transportation (DOT) Regulatory Policies and Procedures (44 FR 11034; February 26.... 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 2. The... Federal Aviation Administration 14 CFR Part 71 RIN 2120-AA66 Proposed Modification of VOR Federal Airway...

  15. Evaluation criteria for commercially oriented materials processing in space proposals

    NASA Technical Reports Server (NTRS)

    Moore, W. F.; Mcdowell, J. R.

    1979-01-01

    An approach and criteria for evaluating NASA funded experiments and demonstrations which have commercial potential were developed. Methods for insuring quick initial screening of commercial proposals are presented. Recommendations are given for modifying the current evaluation approach. New criteria for evaluating commercially orientated materials processing in space (MPS) proposals are introduced. The process for selection of qualified individuals to evaluate the phases of this approach and criteria is considered and guidelines are set for its implementation.

  16. Status of in-situ air stripping tests and proposed modifications: Horizontal wells AMH-1 and AMH-2 Savannah River Site

    SciTech Connect

    Kaback, D.S.; Looney, B.B.

    1989-08-01

    A project to drill and install two horizontal vapor extraction/air injection wells at the Savannah River Site (SRS), Aiken, South Carolina, was performed in September and October of 1988. The project was performed to test the feasibility of horizontal drilling technologies in shallow unconsolidated sediments. Additional study to evaluate the effectiveness of in-situ air stripping of volatile organics from the ground water and unsaturated soils is planned. This status report contains (1) a short summary of the construction details of the two horizontal wells and (2) proposed modifications to the original program plan (Kaback and Looney 1988; Looney and Kaback, 1988). The modifications include added pressure monitoring and use of an inert tracer gas (helium) to better evaluate system performance. This paper contains sections that provide information requested by the South Carolina Department Health and Environmental Control as part of the underground injection well permitting process. 3 refs., 6 figs.

  17. 76 FR 59420 - Proposed Information Collection; Alaska Guide Service Evaluation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-26

    ... Fish and Wildlife Service Proposed Information Collection; Alaska Guide Service Evaluation AGENCY: Fish... Service Evaluation) to help us evaluate commercial guide services on our national wildlife refuges in the.... Data OMB Control Number: 1018-0141. Title: Alaska Guide Service Evaluation. Service Form Number(s):...

  18. Discovering Cooperative Relationships of Chromatin Modifications in Human T Cells Based on a Proposed Closeness Measure

    PubMed Central

    Liu, Hongbo; Wu, Xueting; Zhu, Jiang; Su, Jianzhong; Wang, Fang; Cui, Ying; Zhang, Yan

    2010-01-01

    Background Eukaryotic transcription is accompanied by combinatorial chromatin modifications that serve as functional epigenetic markers. Composition of chromatin modifications specifies histone codes that regulate the associated gene. Discovering novel chromatin regulatory relationships are of general interest. Methodology/Principal Findings Based on the premise that the interaction of chromatin modifications is hypothesized to influence CpG methylation, we present a closeness measure to characterize the regulatory interactions of epigenomic features. The closeness measure is applied to genome-wide CpG methylation and histone modification datasets in human CD4+T cells to select a subset of potential features. To uncover epigenomic and genomic patterns, CpG loci are clustered into nine modules associated with distinct chromatin and genomic signatures based on terms of biological function. We then performed Bayesian network inference to uncover inherent regulatory relationships from the feature selected closeness measure profile and all nine module-specific profiles respectively. The global and module-specific network exhibits topological proximity and modularity. We found that the regulatory patterns of chromatin modifications differ significantly across modules and that distinct patterns are related to specific transcriptional levels and biological function. DNA methylation and genomic features are found to have little regulatory function. The regulatory relationships were partly validated by literature reviews. We also used partial correlation analysis in other cells to verify novel regulatory relationships. Conclusions/Significance The interactions among chromatin modifications and genomic elements characterized by a closeness measure help elucidate cooperative patterns of chromatin modification in transcriptional regulation and help decipher complex histone codes. PMID:21151929

  19. 78 FR 47010 - Proposed Safety Evaluation for Plant-Specific

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-02

    ... COMMISSION Proposed Safety Evaluation for Plant-Specific Technical Specifications Task Force Traveler... requesting public comment on the proposed model safety evaluation (SE) for plant- specific adoption of... ``Begin Web- based ADAMS Search.'' For problems with ADAMS, please contact the NRC's Public Document...

  20. Initial O₂ Insertion Step of the Tryptophan Dioxygenase Reaction Proposed by a Heme-Modification Study.

    PubMed

    Makino, Ryu; Obayashi, Eiji; Hori, Hiroshi; Iizuka, Tetsutaro; Mashima, Keisuke; Shiro, Yoshitsugu; Ishimura, Yuzuru

    2015-06-16

    L-Tryptophan 2,3-dioxygenase (TDO) is a protoheme-containing enzyme that catalyzes the production of N-formylkynurenine by inserting O₂ into the pyrrole ring of L-tryptophan. Although a ferrous-oxy form (Fe²⁺-O₂) has been established to be an obligate intermediate in the reaction, details of the ring opening reaction remain elusive. In this study, the O₂ insertion reaction catalyzed by Pseudomonas TDO (PaTDO) was examined using a heme-modification approach, which allowed us to draw a quantitative correlation between the inductive electronic effects of the heme substituents and the substituent-induced changes in the functional behaviors of the ferrous-oxy form. We succeeded in preparing reconstituted PaTDO with synthetic hemes, which were different with respect to the inductive electron-withdrawing nature of the heme substituents at positions 2 and 4. An increase in the electron-withdrawing power of the heme substituents elevated the redox potential of reconstituted PaTDO, showing that the stronger the electron-withdrawing ability of the heme substituents, the lower the electron density on the heme iron. The decrease in the electron density of the heme iron resulted in a higher frequency shift of the C-O stretch of the heme-bound CO and enhanced the dissociation of O₂ from the ferrous-oxy intermediate. This result was interpreted as being due to weaker π back-donation from the heme iron to the bound CO or O₂. More importantly, the reaction rates of the ferrous-oxy intermediate to oxidize L-Trp were increased with the electron-withdrawing ability of the heme substituents, implying that the more electron-deficient ferrous-oxy heme is favored for the PaTDO-catalyzed oxygenation. On the basis of these results, we propose that the initial step of the dioxygen activation by PaTDO is a direct electrophilic addition of the heme-bound O₂ to the indole ring of L-Trp. PMID:25996254

  1. A Review of The Society for Assisted Reproductive Technology Embryo Grading System and Proposed Modification

    PubMed Central

    Hossain, Amjad; Phelps, John; Agarwal, Ashok; Sanz, Eduardo; Mahadevan, Maha

    2016-01-01

    The Society for Assisted Reproductive Technology (SART) method of embryo grad- ing is unique, simple, and widely practiced, and its use has been mandatory for SART membership programs since 2010. Developed by SART in 2006, the current embryo grading system categories, “good, fair, and poor,” are limited because they do not describe the best 1-2 embryos in the interest of keeping pace with the shift in clinical practice to be more selective and to transfer fewer embryos. This inspired us to conduct a review on the SART embryo grading system. In this retrospective study, the literature on evaluation of human embryo quality in gen- eral, and the SART method of evaluation in particular, were reviewed for the period of 2000 to 2014. A multifaceted search pertaining to methods of embryo grading and trans- fer using a combination of relevant terms [embryo, mammalian, embryo transfer, grade, grading, morphology, biomarkers, SART, and in vitro fertilization (IVF)] was performed. The inclusion and exclusion in this review were dictated by the aim and scope of the study. Two investigators independently assessed the studies and extracted information. A total of 61 articles were reviewed. Very few studies have evaluated the efficacy of the SART embryo grading method. The present study suggests the necessity for revision of the current SART grading system. The system, as it is now, lacks criteria for describing the cohort specific best embryo and thus is of limited use in single embryo transfer. The study foresees heightened descriptive efficiency of the SART system by implementing the proposed changes. Strengths and weaknesses of the SART embryo grading were identified. Ideas for selecting the best cohort-specific embryo have been discussed, which may trigger methodological improvement in SART and other embryo grading systems. PMID:27441045

  2. 75 FR 9538 - Proposed Modification of Class B Airspace; Charlotte, NC

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-03

    ... (ARSA) (54 FR 32604). As a result of the Airspace Reclassification Final Rule (56 FR 65638), which... in 1995 (60 FR 26594). Only minor changes were made at that time. Since that modification, the... Skydive Carolina. As announced in the Federal Register (73 FR 63407), informal airspace meetings were...

  3. 15 CFR 290.6 - Proposal evaluation and selection criteria.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... CENTERS FOR THE TRANSFER OF MANUFACTURING TECHNOLOGY § 290.6 Proposal evaluation and selection criteria...? (i) Market analysis. Demonstrated understanding of the service region's manufacturing base, including.... Physical size, concentration of industry, and economic significance of the service region's...

  4. 48 CFR 1415.207-71 - Confidentiality of proposal evaluation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Confidentiality of proposal evaluation. 1415.207-71 Section 1415.207-71 Federal Acquisition Regulations System DEPARTMENT OF... or content of proposals received to any other party (including supervisors) without the...

  5. Evaluation of optimum profile modification curves of profile shifted spur gears based on vibration responses

    NASA Astrophysics Data System (ADS)

    Ma, Hui; Pang, Xu; Feng, Ranjiao; Wen, Bangchun

    2016-03-01

    In this paper, a mesh stiffness model is developed for profile shifted gears with addendum modifications and tooth profile modifications (TPMs). The time-varying mesh stiffness (TVMS), load sharing factor (LSF), loaded static transmission error (LSTE) and non-loaded static transmission error (NLSTE) of a profile shifted spur gear pair with TPMs are obtained by the analytical model. The optimum profile modification curve under different amounts of TPM is determined by analyzing the LSTE first. Then, considering the effect of NLSTE, finite element (FE) model of a geared rotor system is established. The system vibration responses under different TPM curves are analyzed and the optimum modification curve is further evaluated by amplitude frequency responses. The results show that the optimum modification curve is related to the amount of TPM and modification coefficients. The comparison of the optimum profile modification curves is evaluated by LSTE and vibration responses, which shows that the optimum modification curve should be determined by evaluating the vibration response of the geared rotor system in the low mesh frequency range.

  6. 7 CFR 3406.15 - Evaluation criteria for teaching proposals.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Evaluation criteria for teaching proposals. 3406.15 Section 3406.15 Agriculture Regulations of the Department of Agriculture (Continued) COOPERATIVE STATE RESEARCH, EDUCATION, AND EXTENSION SERVICE, DEPARTMENT OF AGRICULTURE 1890 INSTITUTION CAPACITY BUILDING GRANTS PROGRAM Review and Evaluation of...

  7. 48 CFR 1415.207-71 - Confidentiality of proposal evaluation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... secret information unless authorized by law. (b) At the initial meeting of the committee, the CO shall... by the CO. (d) Bureaus and offices may only release proposals outside the Government for evaluation... the Government for evaluation or advice shall be approved in writing by the HCA; (2)...

  8. 48 CFR 15.208 - Submission, modification, revision, and withdrawal of proposals.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... ACQUISITION REGULATION CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Solicitation and... the contract file when oral withdrawals are made. One copy of withdrawn proposals should be retained in the contract file (see 4.803(a)(10)). Extra copies of the withdrawn proposals may be destroyed...

  9. 78 FR 2646 - Proposed Modification of Class B Airspace; Las Vegas, NV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-14

    ... that was published on October 26, 2012. In that document, the FAA proposed to modify the Las Vegas, NV... FR 65332) closed on December 26, 2012, is reopened until February 13, 2013. ADDRESSES: Send comments... particularly helpful in developing reasoned regulatory decisions on the proposal. Comments are...

  10. 78 FR 11996 - Proposed Modification of Class D and Class E Airspace; Pueblo, CO

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-21

    ...This action proposes to modify Class D airspace and the Class E airspace areas at Pueblo Memorial Airport, Pueblo, CO. Controlled airspace is necessary to accommodate aircraft using VHF Omni- Directional Radio Range/Distance Measuring Equipment (VOR/DME) standard instrument approach procedures at Pueblo Memorial Airport. The FAA is proposing this action to enhance the safety and management of......

  11. 75 FR 2582 - Proposed Modification of the Atlanta, GA, Class B Airspace Area; Public Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-15

    ... Friday, December 4, 2009, concerning a proposal to revise Class B airspace at Atlanta, GA, (74 FR 63818... a proposal to revise Class B airspace at Atlanta, GA, (74 FR 63818). The address and phone number..., in Covington, GA, as published in the Federal Register on Friday, December 4, 2009 (74 FR 63818),...

  12. 76 FR 63235 - Proposed Modification of Class E Airspace; The Dalles, OR

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-12

    ... accommodate aircraft using Area Navigation (RNAV) Global Positioning System (GPS) standard instrument approach... submitted in triplicate to the Docket Management System (see ADDRESSES section for address and phone number... Proposed Rulemaking Distribution System, which describes the application procedure. The Proposal The FAA...

  13. Supervised Evaluation of Image Segmentation and Object Proposal Techniques.

    PubMed

    Pont-Tuset, Jordi; Marques, Ferran

    2016-07-01

    This paper tackles the supervised evaluation of image segmentation and object proposal algorithms. It surveys, structures, and deduplicates the measures used to compare both segmentation results and object proposals with a ground truth database; and proposes a new measure: the precision-recall for objects and parts. To compare the quality of these measures, eight state-of-the-art object proposal techniques are analyzed and two quantitative meta-measures involving nine state of the art segmentation methods are presented. The meta-measures consist in assuming some plausible hypotheses about the results and assessing how well each measure reflects these hypotheses. As a conclusion of the performed experiments, this paper proposes the tandem of precision-recall curves for boundaries and for objects-and-parts as the tool of choice for the supervised evaluation of image segmentation. We make the datasets and code of all the measures publicly available. PMID:26415155

  14. Health insurance reform: modifications to the Health Insurance Portability and Accountability Act (HIPAA) electronic transaction standards. Proposed rule.

    PubMed

    2008-08-22

    This rule proposes to adopt updated versions of the standards for electronic transactions originally adopted in the regulations entitled, "Health Insurance Reform: Standards for Electronic Transactions," published in the Federal Register on August 17, 2000, which implemented some of the requirements of the Administrative Simplification subtitle of the Health Insurance Portability and Accountability Act of 1996 (HIPAA). These standards were modified in our rule entitled, "Health Insurance Reform: Modifications to Electronic Data Transaction Standards and Code Sets," published in the Federal Register on February 20, 2003. This rule also proposes the adoption of a transaction standard for Medicaid Pharmacy Subrogation. In addition, this rule proposes to adopt two standards for billing retail pharmacy supplies and professional services, and to clarify who the "senders" and "receivers" are in the descriptions of certain transactions. PMID:18958949

  15. Dopamine Surface Modification of Trititanate Nanotubes: Proposed In-Situ Structure Models.

    PubMed

    Liu, Ruochen; Fu, Xuejian; Wang, Congyi; Dawson, Graham

    2016-04-18

    Two models for self-assembled dopamine on the surface of trititanate nanotubes are proposed: individual monomer units linked by π-π stacking of the aromatic regions and mono-attached units interacting through hydrogen bonds. This was investigated with solid state NMR spectroscopy studies and powder X-ray diffraction. PMID:27002587

  16. 76 FR 28915 - Proposed Modification of Class E Airspace; Alturas, CA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-19

    ... 71 continues to read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR...: Comments must be received on or before July 5, 2011. ADDRESSES: Send comments on this proposal to the U.S... also be accessed through the FAA's Web page at...

  17. 76 FR 30300 - Proposed Modification of Class E Airspace; Glasgow, MT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-25

    ... 71 continues to read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR... this proposal to the U.S. Department of Transportation, Docket Operations, M-30, West Building Ground... published rulemaking documents can also be accessed through the FAA's Web page at...

  18. 78 FR 25406 - Proposed Modification of Class E Airspace; Twin Falls, ID

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-01

    ... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does... U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71...: This action proposes to modify Class E airspace at Twin Falls Joslin Field-Magic Valley...

  19. 78 FR 76779 - Proposed Modification of the Philadelphia, PA, Class B Airspace Area

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-19

    ...This action proposes to amend the description of Area G of the Philadelphia Class B airspace area to correct a design error that resulted in the Class B airspace being published 2.1 nautical miles (NM) larger on the southeast side of the area than intended. No other changes to the Philadelphia Class B airspace are being...

  20. 78 FR 60238 - Proposed Modification and Establishment of Restricted Areas; Aberdeen Proving Ground, MD

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-01

    ... Aerostats. The Aerostat is a 243-foot long balloon that resembles a blimp in appearance. The balloons would... Maryland. The purpose of the proposed R-4001C is to contain two moored balloons, called Aerostats that... Administration, 800 Independence Avenue SW., Washington, DC 20591; telephone: (202) 267-8783....

  1. 78 FR 40076 - Proposed Establishment and Modification of Class E Airspace; Oakland, CA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-03

    ... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does...), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The... (NPRM). SUMMARY: This action proposes to establish Class E airspace extending upward from 700 feet...

  2. 75 FR 41774 - Proposed Establishment and Modification of Class E Airspace; Deer Park, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-19

    ... Executive Order 12866; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR... continues to read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3...; Deer Park, WA AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of proposed...

  3. 78 FR 70895 - Proposed Establishment and Modification of Area Navigation (RNAV) Routes; Atlanta, GA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-27

    .... This proposed action is intended to enhance air traffic flow in the vicinity of the Atlanta, GA (ATL... Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of a.... 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0...

  4. 78 FR 38389 - Proposed Modification to the Scopes of Recognition of Several NRTLs

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-26

    ...In this notice, OSHA proposes to delete several test standards from the scopes of recognition of several nationally recognized testing laboratories (NRTLs), and to incorporate into the scopes of recognition of several NRTLs test standards to replace some of the deleted test...

  5. 78 FR 76784 - Proposed Modification, Revocation, and Establishment of Area Navigation (RNAV) Routes; Charlotte, NC

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-19

    ... ``significant rule'' under Department of Transportation (DOT) Regulatory Policies and Procedures (44 FR 11034..., 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation by.... The proposed routes, in combination with existing VOR Federal airways, would provide...

  6. 75 FR 27229 - Proposed Modification of Class B Airspace; Chicago, IL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-14

    ...This action proposes to modify the Chicago, IL, Class B airspace area by expanding the existing airspace to ensure containment of Instrument Flight Rules (IFR) aircraft conducting instrument approach procedures within Class B airspace, and segregating IFR aircraft at Chicago O'Hare International Airport (ORD) and Visual Flight Rules (VFR) aircraft operating in the vicinity of Chicago Class B......

  7. 77 FR 53907 - Notice of Proposed Withdrawal Modification and Transfer of Administrative Jurisdiction; Montana

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-04

    ...The Assistant Secretary of the Interior for Policy, Management and Budget proposes to modify Public Land Order (PLO) No. 1843, on behalf of the Bureau of Land Management (BLM), to transfer administrative jurisdiction of 5.16 acres of National Forest System (NFS) land from the U.S. Forest Service (USFS) to the BLM. The BLM would be the primary agency with responsibility and liability for the......

  8. 76 FR 46678 - Tris carbamoyl triazine; Proposed Modification of Significant New Uses

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-03

    ... information sufficient to make reasoned evaluations of the health or environmental effects of this chemical... Strategies Division, Office of Environmental Information (2822T), Environmental Protection Agency, 1200..., entitled Protection of Children from Environmental Health Risks and Safety Risks (62 FR 19885, April...

  9. 15 CFR 290.6 - Proposal evaluation and selection criteria.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... NIST research results and expertise in the technical areas noted in these procedures? (3) Technology delivery mechanisms. Does the proposal clearly and sharply define an effective methodology for delivering.... Effectiveness of the planned methodology of program management. (iii) Internal evaluation. Effectiveness of...

  10. Proposed Evaluation Criteria for Screening Programs for the Elderly.

    ERIC Educational Resources Information Center

    Rogers, John; And Others

    1986-01-01

    Contends that generally accepted criteria for screening asymptomatic individuals are not appropriate for the elderly due to the prevalence of symptoms and chronic problems in the elderly and the importance of tertiary prevention. Proposes evaluation criteria that reflect the goals of screening elderly individuals. (Author/ABB)

  11. Hospital-Based Behavior Modification Program for Adolescents: Evaluation and Predictors of Outcome.

    ERIC Educational Resources Information Center

    Al Ansari, Ahmed; And Others

    1996-01-01

    Evaluates a short-term residential program utilizing a behavior modification program in an outpatient unit for adolescents with mostly conduct problems. Evaluation indicated predictors of outcome, including: age, gender, diagnosis, length of stay, father's presence, other treatments received, and presence of learning problems. Factors such as…

  12. Rendezvous radar modification and evaluation. [for space shuttles

    NASA Technical Reports Server (NTRS)

    1976-01-01

    The purpose of this effort was to continue the implementation and evaluation of the changes necessary to add the non-cooperative mode capability with frequency diversity and a doppler filter bank to the Apollo Rendezvous Radar while retaining the cooperative mode capability.

  13. H Scan/AHP advanced technology proposal evaluation process

    SciTech Connect

    Mack, S.; Valladares, M.R.S. de

    1996-10-01

    It is anticipated that a family of high value/impact projects will be funded by the Hydrogen Program to field test hydrogen technologies that are at advanced stages of development. These projects will add substantial value to the Program in several ways, by: demonstrating successful integration of multiple advanced technologies, providing critical insight on issues of larger scale equipment design, construction and operations management, yielding cost and performance data for competitive analysis, refining and deploying enhanced safety measures. These projects will be selected through a competitive proposal evaluation process. Because of the significant scope and funding levels of projects at these development phases, Program management has indicated the need for an augmented proposal evaluation strategy to ensure that supported projects are implemented by capable investigative teams and that their successful completion will optimally advance programmatic objectives. These objectives comprise a complex set of both quantitative and qualitative factors, many of which can only be estimated using expert judgment and opinion. To meet the above need, the National Renewable Energy Laboratory (NREL) and Energetics Inc. have jointly developed a proposal evaluation methodology called H Scan/AHP. The H Scan component of the process was developed by NREL. It is a two-part survey instrument that substantially augments the type and scope of information collected in a traditional proposal package. The AHP (Analytic Hierarchy Process) component was developed by Energetics. The AHP is an established decision support methodology that allows the Program decision makers to evaluate proposals relatively based on a unique set of weighted criteria that they have determined.

  14. UH-60 Black Hawk engineering simulation model validation and proposed modifications

    NASA Technical Reports Server (NTRS)

    Kaplita, Thaddeus T.

    1986-01-01

    The engineering simulation model of the UH-60A Black Hawk was validated using comparisons of model time histories with flight test data and updated to improve the fidelity of the model. The flight test data, acquired by the Army Aviation Engineering Flight Activity and consisting of 90 time histories of transient responses to step and pulse control inputs and 16 sets of steady flight data, were processed and compared to corresponding model time histories and trim data by Sikorsky. The current UH-60A model was judged to provide an acceptably accurate simulation for use as an analytical tool, certain unsatisfactory areas were identified and potential approaches to produce a more representative simulation were evaluated.

  15. Proposed Modifications to Engineering Design Guidelines Related to Resistivity Measurements and Spacecraft Charging

    NASA Technical Reports Server (NTRS)

    Dennison, J. R.; Swaminathan, Prasanna; Jost, Randy; Brunson, Jerilyn; Green, Nelson; Frederickson, A. Robb

    2005-01-01

    A key parameter in modeling differential spacecraft charging is the resistivity of insulating materials. This determines how charge will accumulate and redistribute across the spacecraft, as well as the time scale for charge transport and dissipation. Existing spacecraft charging guidelines recommend use of tests and imported resistivity data from handbooks that are based principally upon ASTM methods that are more applicable to classical ground conditions and designed for problems associated with power loss through the dielectric, than for how long charge can be stored on an insulator. These data have been found to underestimate charging effects by one to four orders of magnitude for spacecraft charging applications. A review is presented of methods to measure the resistive of highly insulating materials, including the electrometer-resistance method, the electrometer-constant voltage method, the voltage rate-of-change method and the charge storage method. This is based on joint experimental studies conducted at NASA Jet Propulsion Laboratory and Utah State University to investigate the charge storage method and its relation to spacecraft charging. The different methods are found to be appropriate for different resistivity ranges and for different charging circumstances. A simple physics-based model of these methods allows separation of the polarization current and dark current components from long duration measurements of resistivity over day- to month-long time scales. Model parameters are directly related to the magnitude of charge transfer and storage and the rate of charge transport. The model largely explains the observed differences in resistivity found using the different methods and provides a framework for recommendations for the appropriate test method for spacecraft materials with different resistivities and applications. The proposed changes to the existing engineering guidelines are intended to provide design engineers more appropriate methods for

  16. Proposed modification of the Huxley-Simmons model for myosin head motion along an actin filament.

    PubMed

    Mitsui, T; Chiba, H

    1996-09-21

    A model is proposed for myosin head motion along an actin filament which accommodates recent experimental data. The model includes three attached states of a myosin head and is thus similar to the classical Huxley & Simmons (1971) model, but differs in that an explicit expression is given for the spatial distribution of potential energy wells for the myosin head. Our model also differs from the classical model, in that it assumes that the proportion of myosin heads attached to actin filament is constant and independent of shortening velocity, as suggested by X-ray diffraction data. Furthermore, it posits that the crossbridge is string-like rather than spring-like. This modified model fits well to the experimental data in the following respects. (1) The calculated tension dependence of muscle stiffness agrees with the observation by Ford et al. (1985 J. Physiol. 361, 131-150). (2) A myosin head under low load can move as far as 60 nm along an actin filament during one ATP hydrolysis cycle in muscle, in agreement with the results by Yanagida et al. (1985 Nature 316, 366-369) and others. (3) The model predicts that such movements consist of a series of elementary steps of 11 nm. (4) A single myosin head hardly moves after the first step of 11 nm under the condition of in vitro experiment carried out by Finer et al. (1994 Nature 368, 113-119), in agreement with their observation. (5) The calculated energy liberation rate reproduces the characteristics of Hill's equation. (6) The "double-hyperbolic force-velocity relation" reported by Edman (1988 J. Physiol. 404, 301-321) can be understood in terms of a potential barrier against movement of a potential well in which a myosin head is trapped. PMID:8944146

  17. Evaluation of dredged material proposed for ocean disposal from MOTBY

    SciTech Connect

    Barrows, E.S.; Mayhew, H.L.; Word, J.Q.

    1996-09-01

    The National Park Service, US Department of the Interior requested U.S. Army Corps of Engineers/New York District (USACE-NYD) to evaluate sediments around the Military Ocean Terminal (MOTBY) in Bayonne, New Jersey for unconfined ocean disposal at the Mud Dump Site. Sediment samples were collected from MOTBY. Tests and analyses were conducted on MOTBY sediment core samples. The evaluation of proposed dredged material from MOTBY included grain size and total organic carbon (TOC) analyses and one acute toxicity test with the amphipod Ampelisca abdita. In addition to this benthic toxicity test, a bioaccumulation test (28-day exposure) was conducted.

  18. Emergy evaluation perspectives of a multipurpose dam proposal in Korea.

    PubMed

    Kang, Daeseok; Park, Seok Soon

    2002-11-01

    The 'emergy' concept was used to evaluate the economy of Korea and the contributions of a multipurpose dam proposal to the real wealth of the Korean economy. Emergy is defined as the available energy of one kind previously used up directly and indirectly to make a product or service. The indices for Korea calculated from the emergy evaluation were close to those of developed countries. Even though its monetary balance of payments was negative in 1997, the economy of Korea showed positive balance in trade when exports and imports were expressed in emergy. The emergy evaluation showed that the Korean economy places a large stress on its environment. Water supply and generation of electricity were the most important contributions of the proposed dam in terms of emergy; 46.5 and 45.1% of the total benefit, respectively. Flood control contributed 8.4% of the total benefit. Major costs associated with the proposed dam were from sediments (33.2% of the total cost), construction services (22.8%), and social disruption of the region (21.6%). In terms of emergy, the ratio of benefits to costs of the proposed dam was 2.78 if sediments are not included, and 1.86 if sediments are included, which result in more benefits than costs in both cases. The benefit to cost ratio of the dam was larger than that of the current system (1.42) without the dam whether sediments are included in the total cost or not. The environmental stress of the proposed dam was considerably lower than that of the Korean economy, but the dam might increase stress on local environment. PMID:12448407

  19. Evaluation of Proteomic Search Engines for the Analysis of Histone Modifications

    PubMed Central

    2015-01-01

    Identification of histone post-translational modifications (PTMs) is challenging for proteomics search engines. Including many histone PTMs in one search increases the number of candidate peptides dramatically, leading to low search speed and fewer identified spectra. To evaluate database search engines on identifying histone PTMs, we present a method in which one kind of modification is searched each time, for example, unmodified, individually modified, and multimodified, each search result is filtered with false discovery rate less than 1%, and the identifications of multiple search engines are combined to obtain confident results. We apply this method for eight search engines on histone data sets. We find that two search engines, pFind and Mascot, identify most of the confident results at a reasonable speed, so we recommend using them to identify histone modifications. During the evaluation, we also find some important aspects for the analysis of histone modifications. Our evaluation of different search engines on identifying histone modifications will hopefully help those who are hoping to enter the histone proteomics field. The mass spectrometry proteomics data have been deposited to the ProteomeXchange Consortium with the data set identifier PXD001118. PMID:25167464

  20. Evaluation of proteomic search engines for the analysis of histone modifications.

    PubMed

    Yuan, Zuo-Fei; Lin, Shu; Molden, Rosalynn C; Garcia, Benjamin A

    2014-10-01

    Identification of histone post-translational modifications (PTMs) is challenging for proteomics search engines. Including many histone PTMs in one search increases the number of candidate peptides dramatically, leading to low search speed and fewer identified spectra. To evaluate database search engines on identifying histone PTMs, we present a method in which one kind of modification is searched each time, for example, unmodified, individually modified, and multimodified, each search result is filtered with false discovery rate less than 1%, and the identifications of multiple search engines are combined to obtain confident results. We apply this method for eight search engines on histone data sets. We find that two search engines, pFind and Mascot, identify most of the confident results at a reasonable speed, so we recommend using them to identify histone modifications. During the evaluation, we also find some important aspects for the analysis of histone modifications. Our evaluation of different search engines on identifying histone modifications will hopefully help those who are hoping to enter the histone proteomics field. The mass spectrometry proteomics data have been deposited to the ProteomeXchange Consortium with the data set identifier PXD001118. PMID:25167464

  1. RBME coral temperature reconstruction: An evaluation, modifications, and recommendations

    NASA Astrophysics Data System (ADS)

    Sinclair, Daniel J.

    2015-04-01

    Rayleigh-Based Multi-Element (RBME) coral temperature reconstruction (Gaetani et al., 2011) is an important new method potentially allowing accurate ocean temperatures to be reconstructed from aragonitic corals without the need for in-situ calibration. RBME is based on a mathematical model which assumes that trace element uptake into coral skeleton is mediated by (1) temperature-dependent (inorganic) partition coefficients, and (2) a temperature-dependent change in the proportion of ions in a calcifying fluid that are precipitated as CaCO3. A time-series of Sr, Mg and Ba measurements can therefore be formulated as a set of simultaneous equations allowing temperatures and model fit-parameters to be solved numerically by least-squares minimization. Here, I critically review the RBME method, focusing on assumptions underlying the mathematical model, implementation of the numerical scheme, and the accuracy of temperature reconstruction. The equations in the RBME are highly nonlinear, and their number scales with the length of the time-series. These 'high-dimensional nonlinear optimization' problems are characterized by high computational cost, and the difficulty in finding the true 'global' minimum rather than false 'local' minima. Tests show that several of the RBME equations are highly sensitive to changing parameters thereby making it difficult for minimization algorithms to search broadly in parameter space. The method is therefore exceedingly slow and has a very strong tendency to find local optima that are close to the initial guess (which must be supplied by the user) making it very prone to 'operator bias'. Here a new formulation of the RBME system is proposed that allows much faster optimization, and a much broader search of parameter space. Testing of the RBME method reveals a number of problems. Firstly, RBME can produce many solutions to a given set of Sr, Mg and Ba data that are nearly identical in their minimization function (i.e., are equally good) but

  2. Modification and performance evaluation of a mono-valve engine

    NASA Astrophysics Data System (ADS)

    Behrens, Justin W.

    A four-stroke engine utilizing one tappet valve for both the intake and exhaust gas exchange processes has been built and evaluated. The engine operates under its own power, but has a reduced power capacity than the conventional 2-valve engine. The reduction in power is traced to higher than expected amounts of exhaust gases flowing back into the intake system. Design changes to the cylinder head will fix the back flow problems, but the future capacity of mono-valve engine technology cannot be estimated. The back flow of exhaust gases increases the exhaust gas recirculation (EGR) rate and deteriorates combustion. Intake pressure data shows the mono-valve engine requires an advanced intake valve closing (IVC) time to prevent back flow of charge air. A single actuation camshaft with advanced IVC was tested in the mono-valve engine, and was found to improve exhaust scavenging at TDC and nearly eliminated all charge air back flow at IVC. The optimum IVC timing is shown to be approximately 30 crank angle degrees after BDC. The mono-valve cylinder head utilizes a rotary valve positioned above the tappet valve. The open spaces inside the rotary valveand between the rotary valve and tappet valve represent a common volume that needs to be reduced in order to reduce the base EGR rate. Multiple rotary valve configurations were tested, and the size of the common volume was found to have no effect on back flow but a direct effect on the EGR rate and engine performance. The position of the rotary valve with respect to crank angle has a direct effect on the scavenging process. Optimum scavenging occurs when the intake port is opened just after TDC.

  3. EVALUATION OF COMBUSTION MODIFICATION EFFECTS ON EMISSIONS AND EFFICIENCY OF WOOD-FIRED INDUSTRIAL BOILERS

    EPA Science Inventory

    The report gives results of full-scale tests to evaluate combustion modifications (lower excess air and variations in the overfire air system operation) for emission control and efficiency enhancement on two wood-fired industrial boilers. Polycyclic organic matter (POM) was sampl...

  4. Forensic medical evaluations of child maltreatment: a proposed research agenda.

    PubMed

    Dubowitz, Howard; Christian, Cindy W; Hymel, Kent; Kellogg, Nancy D

    2014-11-01

    Physicians play an important role in the forensic evaluation of suspected child abuse and neglect. There has been considerable progress in the medical field, helping distinguish findings related to maltreatment from other conditions or circumstances. Nevertheless, important questions remain. This article covers several of these questions and proposes a research agenda concerning five main topics: sexual abuse, neglect, fractures, abusive head trauma, and physicians work in interdisciplinary settings. The suggestions are hardly inclusive, but offer suggestions the authors think are priorities, and ones that research could reasonably address. By providing some background to gaps in our knowledge, this paper should be of interest to a broader audience than just medical professionals. PMID:25224781

  5. Waveband evaluation of proposed thematic mapper in forest cover classification

    NASA Technical Reports Server (NTRS)

    Latty, R. S.; Hoffer, R. M.

    1981-01-01

    This study involved the evaluation of the characteristics of multispectral scanner data relative to forest cover type mapping, using NASA's NS-001 multispectral scanner to simulate the proposed Thematic Mapper (TM). The objectives were to determine: (1) the optimum number of wavebands to utilize in computer classifications of TM data; (2) which channel combinations provide the highest expected classification accuracy; and (3) the relative merit of each channel in the context of the cover classes examined. Transformed divergence was used as a measure of statistical distance between spectral class densities associated with each of twelve cover classes. The maximum overall mean pair-wise transformed divergence was used as the basis for evaluating all possible waveband combinations available for use in computer-assisted forest cover classifications.

  6. Quality framework proposal for Component Material Evaluation (CME) projects.

    SciTech Connect

    Christensen, Naomi G.; Arfman, John F.; Limary, Siviengxay

    2008-09-01

    This report proposes the first stage of a Quality Framework approach that can be used to evaluate and document Component Material Evaluation (CME) projects. The first stage of the Quality Framework defines two tools that will be used to evaluate a CME project. The first tool is used to decompose a CME project into its essential elements. These elements can then be evaluated for inherent quality by looking at the subelements that impact their level of quality maturity or rigor. Quality Readiness Levels (QRLs) are used to valuate project elements for inherent quality. The Framework provides guidance for the Principal Investigator (PI) and stakeholders for CME project prerequisites that help to ensure the proper level of confidence in the deliverable given its intended use. The Framework also Provides a roadmap that defined when and how the Framework tools should be applied. Use of these tools allow the Principal Investigator (PI) and stakeholders to understand what elements the project will use to execute the project, the inherent quality of the elements, which of those are critical to the project and why, and the risks associated to the project's elements.

  7. Evaluation of replacement protocols and modifications to TCP to enhance ASC Wide Area Network performance.

    SciTech Connect

    Romero, Randy L. Jr.

    2004-09-01

    Historically, TCP/IP has been the protocol suite used to transfer data throughout the Advanced Simulation and Computing (ASC) community. However, TCP was developed many years ago for an environment very different from the ASC Wide Area Network (WAN) of today. There have been numerous publications that hint of better performance if modifications were made to the TCP algorithms or a different protocol was used to transfer data across a high bandwidth, high delay WAN. Since Sandia National Laboratories wants to maximize the ASC WAN performance to support the Thor's Hammer supercomputer, there is strong interest in evaluating modifications to the TCP protocol and in evaluating alternatives to TCP, such as SCTP, to determine if they provide improved performance. Therefore, the goal of this project is to test, evaluate, compare, and report protocol technologies that enhance the performance of the ASC WAN.

  8. A proposal of microtomography evaluation for restoration interface gaps.

    PubMed

    Meleo, Deborah; Manzon, Licia; Pecci, Raffaella; Zuppante, Francesca; Bedini, Rossella

    2012-01-01

    Nowadays, several adhesive systems are used in dental restoration and they are evaluated by clinical research. In vitro evaluations are often made by means of traditional observation techniques (for example scanning electron microscope (SEM), while 3D cone-beam microtomography technique (3D micro-CT), that can be able to generate 3D sample images without any sample treatment during acquisition data, is going to be used a lot in the next few years. In dental cavity restored with composite, it is possible to predict the presence of gaps due to polymerization shrinkage; that is the reason this work purpose is to reveal by 3D images and measure by micro-CT analysis the voids generated applying the most used adhesive systems at the moment. By means of microtomographic analysis is proposed an aid to overcome bidimensional SEM investigation limits like random observation of sample surface, sample sectioning (to see inside it with the relative possible structural alterations induced on the same sample) and the gold sputtering treatment. For this experimental work, human crown teeth have been selected, all restored with the same composite material, using five adhesive systems. After about 48 hours each tooth has been acquired by means of Skyscan 1072 micro-CT instrument and then processed by 3D reconstruction and micro-CT analyser software. Three adhesive systems have showed 3D micro-CT images with not as much voids as expected, with a very little extent. This kind of micro-CT in vitro evaluation proposal suggests a method to observe and quantify the voids generated after polymerization shrinkage during tooth restoration. PMID:22456021

  9. Science Base and Tools for Evaluating Stream Restoration Project Proposals.

    NASA Astrophysics Data System (ADS)

    Cluer, B.; Thorne, C.; Skidmore, P.; Castro, J.; Pess, G.; Beechie, T.; Shea, C.

    2008-12-01

    Stream restoration, stabilization, or enhancement projects typically employ site-specific designs and site- scale habitat improvement projects have become the default solution to many habitat problems and constraints. Such projects are often planned and implemented without thorough consideration of the broader scale problems that may be contributing to habitat degradation, attention to project resiliency to flood events, accounting for possible changes in climate or watershed land use, or ensuring the long term sustainability of the project. To address these issues, NOAA Fisheries and USFWS have collaboratively commissioned research to develop a science document and accompanying tools to support more consistent and comprehensive review of stream management and restoration projects proposals by Service staff responsible for permitting. The science document synthesizes the body of knowledge in fluvial geomorphology and presents it in a way that is accessible to the Services staff biologists, who are not trained experts in this field. Accompanying the science document are two electronic tools: a Project Information Checklist to assist in evaluating whether a proposal includes all the information necessary to allow critical and thorough project evaluation; and a Project Evaluation Tool (in flow chart format) that guides reviewers through the steps necessary to critically evaluate the quality of the information submitted, the goals and objectives of the project, project planning and development, project design, geomorphic-habitat-species relevance, and risks to listed species. Materials for training Services staff and others in the efficient use of the science document and tools have also been developed. The longer term goals of this effort include: enabling consistent and comprehensive reviews that are completed in a timely fashion by regulators; facilitating improved project planning and design by proponents; encouraging projects that are attuned to their watershed

  10. Evaluating a Proposed 20% National Renewable Portfolio Standard

    SciTech Connect

    Logan, J.; Sullivan, P.; Short, W.; Bird, L.; James, T. L.; Shah, M. R.

    2009-02-01

    This paper provides a preliminary analysis of the impacts of a proposed 20% national renewable portfolio standard (RPS) by 2021, which has been advanced in the U.S. Congress by Senator Jeff Bingaman of New Mexico. The paper was prepared before the America Recovery and Reinvestment Act was signed into law by President Barack Obama on February 17, 2009, and thus does not consider important changes in renewable energy (RE) policy that need to be addressed in follow-on analysis. We use NREL's Regional Energy Deployment System (ReEDS) model to evaluate the impacts of the RPS requirements on the energy sector and consider design issues associated with renewable energy certificate (REC) trading markets.

  11. Evaluation of materials proposed for use in space flight

    NASA Technical Reports Server (NTRS)

    Duncan, W. C.

    1981-01-01

    The primary irritancy and allergenicity of flame resistant treated cotton knit shirts proposed for use in space flight were evaluated. The knitted shirts were supplied by NASA as follows: knitted shirts with collars were made of two-ply mercerized single-knit cotton jersey. The fabric was treated with tetrakis (hydroxymethyl) phosphonium hydroxide and subsequently cured with gaseous ammonia (THPOH/NH3). The final treatment comprised adding on diammonium phosphate (DAP)/urea. The treated fabric was process scoured to remove extraneous materials, top softened and mechanically or chemically finished as required for specific needs. Diammonium phosphate is a more efficient flame inhabitant than the phosphonium; thus, the combination treatment served to impart higher resistance to ignition and sustained combustion as required by NASA test standard.

  12. Evaluating the potential effectiveness of proposed environmental justice initiatives

    SciTech Connect

    Greenfield, N.L.; Namovicz, C.R.

    1994-12-31

    Congress directed the US Environmental Protection Agency (EPA) to create the Technical Assistance Grant (TAG) program to address the concerns of these citizens and, thereby improve community relations at Superfund sites. TAGs provide funding to allow affected residents to hire independent scientific and technical consultants to help them understand the issues at the site and better participate in remedy selection. This study will not directly assess the experience of Environmental Justice sites within the Superfund program. Rather, this study examines existing data on TAGs and the applicability of an expanded TAG program in addressing expressed Environmental Justice concerns. Specifically, the study compares the characteristics of sites with TAGs to a matched control group of sites/communities without TAGs. The study establishes a rigorous statistical baseline upon which it can evaluate the marginal contribution of outreach initiatives to the needs and concerns of minority and low income communities. The results of these analyses will serve as a foundation for evaluating proposed changes in the scope and emphasis of Superfund`s community relations and Environmental Justice outreach programs.

  13. Proposed amendment to presidential permit PP-63 and associated modifications to 500 kV international transmission line, Forbes, Minnesota to Manitoba, Canada. [Forbes Substation

    SciTech Connect

    Not Available

    1992-10-01

    This Addendum to the Final Environmental Assessment for the Proposed Amendment to Presidential Permit PP-63 and Associated Modifications to 500 kV International Transmission Line: Forbes, Minnesota to Manitoba, Canada (DOE/EA-587) addresses Northern States Power Company's (NSP) proposed expansion of the Forbes Substation. The applicant has requested that the expansion take place on the west side of the substation, within the existing property line, instead of on the north side as originally proposed. All of the proposed construction would take place on property already owned by NSP. DOE has reviewed the environmental impacts associated with this minor modification and has determined that the conclusions reached in the environmental assessment and Finding of No Significant Impact prepared in connection with NSP's original amendment request remain valid.

  14. 77 FR 9876 - Proposed Modification of VOR Federal Airways V-10, V-12, and V-508 in the Vicinity of Olathe, KS

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-21

    ... Department of Transportation (DOT) Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and.... 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 2. The... TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 RIN 2120-AA66 Proposed Modification of VOR...

  15. Evaluation of Gene Modification Strategies for the Development of Low-Alcohol-Wine Yeasts

    PubMed Central

    Kutyna, D. R.; Solomon, M. R.; Black, C. A.; Borneman, A.; Henschke, P. A.; Pretorius, I. S.; Chambers, P. J.

    2012-01-01

    Saccharomyces cerevisiae has evolved a highly efficient strategy for energy generation which maximizes ATP energy production from sugar. This adaptation enables efficient energy generation under anaerobic conditions and limits competition from other microorganisms by producing toxic metabolites, such as ethanol and CO2. Yeast fermentative and flavor capacity forms the biotechnological basis of a wide range of alcohol-containing beverages. Largely as a result of consumer demand for improved flavor, the alcohol content of some beverages like wine has increased. However, a global trend has recently emerged toward lowering the ethanol content of alcoholic beverages. One option for decreasing ethanol concentration is to use yeast strains able to divert some carbon away from ethanol production. In the case of wine, we have generated and evaluated a large number of gene modifications that were predicted, or known, to impact ethanol formation. Using the same yeast genetic background, 41 modifications were assessed. Enhancing glycerol production by increasing expression of the glyceraldehyde-3-phosphate dehydrogenase gene, GPD1, was the most efficient strategy to lower ethanol concentration. However, additional modifications were needed to avoid negatively affecting wine quality. Two strains carrying several stable, chromosomally integrated modifications showed significantly lower ethanol production in fermenting grape juice. Strain AWRI2531 was able to decrease ethanol concentrations from 15.6% (vol/vol) to 13.2% (vol/vol), whereas AWRI2532 lowered ethanol content from 15.6% (vol/vol) to 12% (vol/vol) in both Chardonnay and Cabernet Sauvignon juices. Both strains, however, produced high concentrations of acetaldehyde and acetoin, which negatively affect wine flavor. Further modifications of these strains allowed reduction of these metabolites. PMID:22729542

  16. Technical evaluation of proposed Ukrainian Central Radioactive Waste Processing Facility

    SciTech Connect

    Gates, R.; Glukhov, A.; Markowski, F.

    1996-06-01

    This technical report is a comprehensive evaluation of the proposal by the Ukrainian State Committee on Nuclear Power Utilization to create a central facility for radioactive waste (not spent fuel) processing. The central facility is intended to process liquid and solid radioactive wastes generated from all of the Ukrainian nuclear power plants and the waste generated as a result of Chernobyl 1, 2 and 3 decommissioning efforts. In addition, this report provides general information on the quantity and total activity of radioactive waste in the 30-km Zone and the Sarcophagus from the Chernobyl accident. Processing options are described that may ultimately be used in the long-term disposal of selected 30-km Zone and Sarcophagus wastes. A detailed report on the issues concerning the construction of a Ukrainian Central Radioactive Waste Processing Facility (CRWPF) from the Ukrainian Scientific Research and Design institute for Industrial Technology was obtained and incorporated into this report. This report outlines various processing options, their associated costs and construction schedules, which can be applied to solving the operating and decommissioning radioactive waste management problems in Ukraine. The costs and schedules are best estimates based upon the most current US industry practice and vendor information. This report focuses primarily on the handling and processing of what is defined in the US as low-level radioactive wastes.

  17. Flight evaluation of modifications to a digital electronic engine control system in an F-15 airplane

    NASA Technical Reports Server (NTRS)

    Burcham, F. W., Jr.; Myers, L. P.; Zeller, J. R.

    1983-01-01

    The third phase of a flight evaluation of a digital electronic engine control system in an F-15 has recently been completed. It was found that digital electronic engine control software logic changes and augmentor hardware improvements resulted in significant improvements in engine operation. For intermediate to maximum power throttle transients, an increase in altitude capability of up to 8000 ft was found, and for idle to maximum transients, an increase of up to 4000 ft was found. A nozzle instability noted in earlier flight testing was investigated on a test engine at NASA Lewis Research Center, a digital electronic engine control software logic change was developed and evaluated, and no instability occurred in the Phase 3 flight evaluation. The backup control airstart modification was evaluated, and gave an improvement of airstart capability by reducing the minimum airspeed for successful airstarts by 50 to 75 knots.

  18. Sustainable urban housing in Kathmandu, Nepal: Proposals and evaluations

    NASA Astrophysics Data System (ADS)

    Shrestha, Vikas

    quantifies the embodied energy of basic building materials that are used in Nepal; proposes new types of locally-produced insulation; and develops a sustainable design evaluation system based on LEED. This integrated system of sustainable materials database, evaluation system, and vernacular-based housing prototypes developed in this dissertation lays out an example for other third world countries.

  19. Technical evaluation of the CG-47201 6V-92 detroit diesel electronic control (DDEC) propulsion modification. Final report

    SciTech Connect

    Latas, R.M.

    1995-03-01

    This report describes the testing and evaluation (TE) of the CG-47201 6V-92 DDEC Propulsion Modification that was conducted at Coast Guard Station Cape May, New Jersey, during the period 8-12 November 1994.

  20. Evaluation of Lower Umatilla River Channel Modifications Below Three Mile Dam, 1984 Annual Progress Report.

    SciTech Connect

    Nigro, Anthony A.; Ward, David L.

    1985-05-01

    This report summarizes results of the first year of a study initiated in September 1984 to evaluate the adequacy of channel modifications made in the lower Umatilla River to improve adult anadromous salmonid passage to Three Mile Dam (RKm 5.6), determine if fish passage or delay problems exist at Three Mile Dam and recommend site specific corrective measures if needed. Movements of steelhead (Salmo gairdneri) were monitored using mark and recapture and radio telemetry techniques. Thirty-four steelhead were marked with T-anchor tags and released in the lower river. Fifteen of those marked were also fitted with radio transmitters. Three radiotagged steelhead migrated through channel modifications to Three Mile Dam. Two of these fish migrated to the dam in less than 26 hours, but held just below the dam for 7 and 10 days before entering the ladders. The third steelhead delayed for 30 days and entered the west ladder within 24 hours of arrival at the dam. Two other radiotagged steelhead moved upstream through some of the channel modifications but did not migrate to the dam. Only one of 19 marked steelhead not fitted with transmitters was recovered at Three Mile Dam. 14 refs., 18 figs., 3 tabs.

  1. Evaluating Federal Water Projects: A Critique of Proposed Standards

    ERIC Educational Resources Information Center

    Cicchetti, Charles J.; And Others

    1973-01-01

    Questions the feasibility of, and validity of the concepts behind, some of the new procedures proposed by the Water Resources Council. Concludes that the proposed procedures, if accepted in their present form, will bias water resource management in favor of development and against the preservation of the natural environment. (JR)

  2. 76 FR 18615 - 30-Day Notice of Proposed Information Collection: Performance Measurement, Evaluation and Public...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-04

    ... Notice of Proposed Information Collection: Performance Measurement, Evaluation and Public Diplomacy Program Surveys ACTION: Notice of request for public comment and submission to OMB of proposed collection... Reduction Act of 1995. Title of Information Collection: Performance Measurement, Evaluation and...

  3. 77 FR 35408 - Proposed Collection; Comment Request: Process Evaluation of the Early Independence Award (EIA...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-13

    ... HUMAN SERVICES National Institutes of Health Proposed Collection; Comment Request: Process Evaluation of... approval. Proposed Collection: Title: Process Evaluation of the Early Independence Award (EIA) Program... for applications (RFAs) are meeting the needs of applicants, (2) document the selection process,...

  4. Proposed 237U Evaluation for the next ENDL Release

    SciTech Connect

    Brown, D; Summers, N; Thompson, I; Younes, W

    2007-11-07

    We detail the new LLNL evaluation of {sup 237}U for inclusion in both the next release of the ENDL and ENDF/B-VII databases. This evaluation is based on a combination of TALYS calculations, data fits and the earlier JEFF-3.1 evaluation. Our evaluation is in excellent agreement with published surrogate (n, f) data [11, 12, 13, 14, 18] and the unpublished LLNL surrogate (n,2n) data [16].

  5. 78 FR 5761 - Proposed Modification of Significant New Uses of Ethaneperoxoic Acid, 1,1-Dimethylpropyl Ester

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-28

    ... of June 26, 1990 (55 FR 26102), EPA published a final SNUR (codified at Sec. 721.1560 and... and reference: June 26, 1990 (55 FR 26111). Basis for modification of the SNUR: The TSCA section 5(e... outlined in Unit II. of this document and in the Federal Register document of June 26, 1990 (55 FR...

  6. Proposal and Evaluation of Functionally Specialized CMA-ES

    NASA Astrophysics Data System (ADS)

    Akimoto, Youhei; Sakuma, Jun; Ono, Isao; Kobayashi, Shigenobu

    This paper aims the design of efficient and effective optimization algorithms for function optimization. For that purpose we present a new framework of the derandomized evolution strategy with covariance matrix adaptation, which combines the hybrid step size adaptation that is proposed in this paper as a robust alternate to the cumulative step size adaptation and normalization mechanism of covariance matrix. Experiment is conducted on 8 classical unimodal and multimodal test functions and the performance of the proposed strategy is compared with that of the standard strategy. Results show that the proposed strategy beats the standard strategy when the population size becomes larger than the default one, while the performance of proposed strategy is as well or better than that of the standard strategy under the default population size.

  7. Proposed modifications to the RCRA post-closure permit for the Bear Creek Hydrogeologic Regime at the US Department of Energy Y-12 Plant, Oak Ridge, Tennessee

    SciTech Connect

    1997-05-01

    This report presents proposed modifications to several conditions of the Resource Conservation and Recovery Act (RCRA) Post-Closure Permit (PCP) for the Bear Creek Hydrogeologic Regime (BCHR). These permit conditions define the requirements for RCRA post-closure corrective action groundwater monitoring at the S-3 Ponds, the Oil Landfarm, and the Bear Creek Burial Grounds (units A, C-West, and Walk-in Pits). Modification of these PCP conditions is requested to: (1) clarify the planned integration of RCRA post-closure corrective action groundwater monitoring with the monitoring program to be established in the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) Record of Decision (ROD) for the Bear Creek Valley (BCV) Watershed, (2) revise several of the current technical requirements for groundwater monitoring based on implementation of the RCRA post-closure corrective action monitoring program during 1996, and (3) update applicable technical procedures with revised versions recently issued by the Y-12 Plant Groundwater Protection Program (GWPP). With these modifications, the Y-12 Plant will continue to meet the full intent of all regulatory obligations for post-closure care of these facilities. Section 2.0 provides the technical justification for each proposed permit modification. The proposed changes to permit language are provided in Section 3.0 (S-3 Ponds), Section 4.0 (Oil Landfarm), and Section 5.0 (Bear Creek Burial Grounds). Sections 6.0 and 7.0 reference updated and revised procedures for groundwater sampling, and monitoring well plugging and abandonment, respectively. Appendix A includes all proposed revisions to the PCP Attachments.

  8. Use of MATHEW/ADPIC for the evaluation of the environmental impact of proposed OTEC plants. Phase I. Final report

    SciTech Connect

    Rosen, L.C.; Lange, R.; Walker, H.

    1982-11-01

    The MATHEW/ADPIC models are employed in the first phase of a project to evaluate the environmental impact of proposed OTEC plants off the coast of Hawaii. The MATHEW/ADPIC models developed to assess regional plume transport in the atmospheric boundary layer are described. The code modifications of MATHEW/ADPIC required for the OTEC calculation are detailed. A number of test cases are examined. The calculations indicate that the MATHEW/ADPIC codes may be utilized to provide physically reasonable results for the hydrological problems considered.

  9. A Proposed Methodology for Contextualised Evaluation in Higher Education

    ERIC Educational Resources Information Center

    Nygaard, Claus; Belluigi, Dina Zoe

    2011-01-01

    This paper aims to inspire stakeholders working with quality of higher education (such as members of study boards, study programme directors, curriculum developers and teachers) to critically consider their evaluation methods in relation to a focus on student learning. We argue that many of the existing methods of evaluation in higher education…

  10. 77 FR 69539 - 30-Day Notice of Proposed Information Collection: Humphrey Evaluation Survey

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-19

    ... Notice of Proposed Information Collection: Humphrey Evaluation Survey ACTION: Notice of request for... Information Collection: Humphrey Evaluation Survey. OMB Control Number: None. Type of Request: New Collection. Originating Office: Bureau of Educational and Cultural Affairs, Office of Policy and Evaluation,...

  11. 77 FR 43899 - 60-Day Notice of Proposed Information Collection: Humphrey Evaluation Survey

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-26

    ... Notice of Proposed Information Collection: Humphrey Evaluation Survey ACTION: Notice of request for... accordance with the Paperwork Reduction Act of 1995. Title of Information Collection: Humphrey Evaluation.... Originating Office: Bureau of Educational and Cultural Affairs, Office of Policy and Evaluation,...

  12. 76 FR 33395 - 30-Day Notice of Proposed Information Collections: ECA Sports & Culture Evaluation Surveys

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-08

    ... Notice of Proposed Information Collections: ECA Sports & Culture Evaluation Surveys ACTION: Notice of... Information Collection: Sports & Culture Evaluation, Between the Lines (BTL) Survey. OMB Control Number: None... Respond: Voluntary. Title of Information Collection: Sports & Culture Evaluation, Sports Envoys...

  13. 77 FR 6168 - 60-Day Notice of Proposed Information Collection: English Language Evaluation Surveys, OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-07

    ... Notice of Proposed Information Collection: English Language Evaluation Surveys, OMB Control Number 1405... Information Collection: English Language Evaluation: Fulbright English Teaching Assistantship (ETA) Program...: Voluntary. Title of Information Collection: English Language Evaluation: English Language Specialist...

  14. 7 CFR 3406.20 - Evaluation criteria for research proposals.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...-business enterprises? What are the probabilities of the proposed activity or line of inquiry being pursued...? To what degree does the venture reflect a unique approach that is new to the applicant institution or new to the entire field of study? 10 points. (4) Products and results—Are the expected products...

  15. 7 CFR 3406.20 - Evaluation criteria for research proposals.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...-business enterprises? What are the probabilities of the proposed activity or line of inquiry being pursued...? To what degree does the venture reflect a unique approach that is new to the applicant institution or new to the entire field of study? 10 points. (4) Products and results—Are the expected products...

  16. 7 CFR 3406.20 - Evaluation criteria for research proposals.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...-business enterprises? What are the probabilities of the proposed activity or line of inquiry being pursued...? To what degree does the venture reflect a unique approach that is new to the applicant institution or new to the entire field of study? 10 points. (4) Products and results—Are the expected products...

  17. CRITERIA FOR EVALUATION OF PROPOSED PROTOZOAN DETECTION METHODS.

    EPA Science Inventory

    There has been a proliferation of techniques and methods reported for analysis of water samples to determine the presence of the protozoan pathogens Cryptosporidium parvum and Giardia lamblia. Many of the proposed methods are presented as complete procedures, which include sampli...

  18. Evaluation of exercise-respiratory system modifications and integration schemes for physiological systems

    NASA Technical Reports Server (NTRS)

    Gallagher, R. R.

    1974-01-01

    Exercise subroutine modifications are implemented in an exercise-respiratory system model yielding improvement of system response to exercise forcings. A more physiologically desirable respiratory ventilation rate in addition to an improved regulation of arterial gas tensions and cerebral blood flow is observed. A respiratory frequency expression is proposed which would be appropriate as an interfacing element of the respiratory-pulsatile cardiovascular system. Presentation of a circulatory-respiratory system integration scheme along with its computer program listing is given. The integrated system responds to exercise stimulation for both nonstressed and stressed physiological states. Other integration possibilities are discussed with respect to the respiratory, pulsatile cardiovascular, thermoregulatory, and the long-term circulatory systems.

  19. Evaluation of textiles proposed for spacecraft crew apparel

    NASA Technical Reports Server (NTRS)

    Duncan, W. C.

    1976-01-01

    Textiles proposed for spacecraft wearing apparel were tested for possible primary irritancy and allergenicity using guinea pigs and human subjects. The materials submitted for testing were: (1) blue, loosely knit fabric of a copolymer of chlorotrifluoroethylene and ethylene (CTFE), (2) a white fabric, 100% cotton double knit, treated with fire retardant Tetrakis (hydroxymethyl) phosphonium hydroxide/ammonia, and (3) a gold colored polyimide fabric. There were no adverse reactions to any of the fabrics.

  20. 48 CFR 1515.305-71 - Documentation of proposal evaluation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Ethics ethics provisions at 5 CFR part 2635. (c) Any information which might reveal that an offeror has... evaluation documentation shall include: (a) Score sheets prepared by each individual team member must be made... specifically developed for the solicitation; and (b) A statement that the respective team members are free...

  1. 15 CFR 290.6 - Proposal evaluation and selection criteria.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE NIST EXTRAMURAL PROGRAMS REGIONAL.... (a) In making a decision whether to provide financial support, NIST shall review and evaluate all... NIST research results and expertise in the technical areas noted in these procedures? (3)...

  2. 15 CFR 290.6 - Proposal evaluation and selection criteria.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE NIST EXTRAMURAL PROGRAMS REGIONAL.... (a) In making a decision whether to provide financial support, NIST shall review and evaluate all... NIST research results and expertise in the technical areas noted in these procedures? (3)...

  3. 15 CFR 290.6 - Proposal evaluation and selection criteria.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE NIST EXTRAMURAL PROGRAMS REGIONAL.... (a) In making a decision whether to provide financial support, NIST shall review and evaluate all... NIST research results and expertise in the technical areas noted in these procedures? (3)...

  4. 77 FR 71734 - Proposed Modification of the Miami, FL, Class B Airspace Area; and the Ft Lauderdale, FL, Class C...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-04

    ...This notice announces three fact-finding informal airspace meetings to solicit information from airspace users and others, concerning a proposal to revise the Class B airspace at Miami, FL, and the Class C airspace at Ft Lauderdale, FL. The purpose of these meetings is to provide interested parties an opportunity to present views, recommendations, and comments on the proposal. All comments......

  5. 36 CFR 51.16 - How will the Director evaluate proposals and select the best one?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... evaluate proposals and select the best one? 51.16 Section 51.16 Parks, Forests, and Public Property... Procedures § 51.16 How will the Director evaluate proposals and select the best one? (a) The Director will apply the selection factors set forth in § 51.17 by assessing each timely proposal under each of...

  6. 36 CFR 1206.62 - Who reviews and evaluates grant proposals?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... grant proposals? 1206.62 Section 1206.62 Parks, Forests, and Public Property NATIONAL ARCHIVES AND... NHPRC Grants § 1206.62 Who reviews and evaluates grant proposals? (a) State boards. State historical records advisory boards may evaluate your proposal according to Commission grant opportunity...

  7. 36 CFR 1206.62 - Who reviews and evaluates grant proposals?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... grant proposals? 1206.62 Section 1206.62 Parks, Forests, and Public Property NATIONAL ARCHIVES AND... NHPRC Grants § 1206.62 Who reviews and evaluates grant proposals? (a) State boards. State historical records advisory boards may evaluate your proposal according to Commission grant opportunity...

  8. 36 CFR 1206.62 - Who reviews and evaluates grant proposals?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... grant proposals? 1206.62 Section 1206.62 Parks, Forests, and Public Property NATIONAL ARCHIVES AND... NHPRC Grants § 1206.62 Who reviews and evaluates grant proposals? (a) State boards. State historical records advisory boards may evaluate your proposal according to Commission grant opportunity...

  9. 36 CFR 1206.62 - Who reviews and evaluates grant proposals?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... grant proposals? 1206.62 Section 1206.62 Parks, Forests, and Public Property NATIONAL ARCHIVES AND... NHPRC Grants § 1206.62 Who reviews and evaluates grant proposals? (a) State boards. State historical records advisory boards may evaluate your proposal according to Commission grant opportunity...

  10. 36 CFR 51.16 - How will the Director evaluate proposals and select the best one?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... evaluate proposals and select the best one? 51.16 Section 51.16 Parks, Forests, and Public Property... Procedures § 51.16 How will the Director evaluate proposals and select the best one? (a) The Director will apply the selection factors set forth in § 51.17 by assessing each timely proposal under each of...

  11. 23 CFR Appendix D to Subpart A of... - Guidance Criteria for Evaluating Requests for Modifications to the National Highway System

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Guidance Criteria for Evaluating Requests for Modifications to the National Highway System D Appendix D to Subpart A of Part 470 Highways FEDERAL HIGHWAY.... 470, Subpt. A, App. D Appendix D to Subpart A of Part 470—Guidance Criteria for Evaluating...

  12. 23 CFR Appendix D to Subpart A of... - Guidance Criteria for Evaluating Requests for Modifications to the National Highway System

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Guidance Criteria for Evaluating Requests for Modifications to the National Highway System D Appendix D to Subpart A of Part 470 Highways FEDERAL HIGHWAY.... 470, Subpt. A, App. D Appendix D to Subpart A of Part 470—Guidance Criteria for Evaluating...

  13. 15 CFR 400.26 - Criteria for evaluation of applications for expansions, subzones or other modifications of zones.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 15 Commerce and Foreign Trade 2 2013-01-01 2013-01-01 false Criteria for evaluation of applications for expansions, subzones or other modifications of zones. 400.26 Section 400.26 Commerce and... Authority § 400.26 Criteria for evaluation of applications for expansions, subzones or other...

  14. 15 CFR 400.26 - Criteria for evaluation of applications for expansions, subzones or other modifications of zones.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 15 Commerce and Foreign Trade 2 2014-01-01 2014-01-01 false Criteria for evaluation of applications for expansions, subzones or other modifications of zones. 400.26 Section 400.26 Commerce and... Authority § 400.26 Criteria for evaluation of applications for expansions, subzones or other...

  15. Evaluation of an interprofessional team-based learning nutrition and lifestyle modification course.

    PubMed

    Pogge, Elizabeth

    2016-01-01

    An interprofessional, team-based learning elective was developed, implemented, and evaluated to determine the knowledge gained, attitude changes towards interprofessional education, and overall satisfaction with the course. Thirty participants, 14 osteopathic medicine students and 16 pharmacy students, completed the course. The majority of students (88-96%) responded favourably to the team-based learning aspects of the course. Knowledge about nutrition and lifestyle modification was significantly improved by taking the course. Overall, students' readiness for and perception of interprofessional learning improved by taking the course, although not all improvements were statistically significant. In conclusion, the benefits of team-based learning, such as enhancing communication and teamwork skills, can enhance interprofessional education. PMID:26934200

  16. Modification and evaluation of a Barnes-type objective analysis scheme for surface meteorological data

    NASA Technical Reports Server (NTRS)

    Smith, D. R.

    1982-01-01

    The Purdue Regional Objective Analysis of the Mesoscale (PROAM) is a Barness-type scheme for the analysis of surface meteorological data. Modifications are introduced to the original version in order to increase its flexibility and to permit greater ease of usage. The code was rewritten for an interactive computer environment. Furthermore, a multiple iteration technique suggested by Barnes was implemented for greater accuracy. PROAM was subjected to a series of experiments in order to evaluate its performance under a variety of analysis conditions. The tests include use of a known analytic temperature distribution in order to quantify error bounds for the scheme. Similar experiments were conducted using actual atmospheric data. Results indicate that the multiple iteration technique increases the accuracy of the analysis. Furthermore, the tests verify appropriate values for the analysis parameters in resolving meso-beta scale phenomena.

  17. Evaluation of a proposed method for representing drug terminology.

    PubMed

    Cimino, J J; McNamara, T J; Meredith, T; Broverman, C A; Eckert, K C; Moore, M; Tyree, D J

    1999-01-01

    In the absence of a single, standard, multipurpose terminology for representing medications, the HL7 Vocabulary Technical Committee has sought to develop a model for such terms in a way that will provide a unified method for representing them and supporting interoperability among various terminology systems. We evaluated the preliminary model by obtaining terms, represented in our model, from three leading vendors of pharmacy system knowledge bases. A total of 2303 terms were obtained, and 3982 pair-wise comparisons were possible. We found that the components of the term descriptions matched 68-87% of the time and that the overall descriptions matched 53% of the time. The evaluation has identified a number of areas in the model where more rigorous definitions will be needed in order to improve the matching rate. This paper discusses the implications of these results. PMID:10566318

  18. Evaluation of Grid Modification Methods for On- and Off-Track Sonic Boom Analysis

    NASA Technical Reports Server (NTRS)

    Nayani, Sudheer N.; Campbell, Richard L.

    2013-01-01

    Grid modification methods have been under development at NASA to enable better predictions of low boom pressure signatures from supersonic aircraft. As part of this effort, two new codes, Stretched and Sheared Grid - Modified (SSG) and Boom Grid (BG), have been developed in the past year. The CFD results from these codes have been compared with ones from the earlier grid modification codes Stretched and Sheared Grid (SSGRID) and Mach Cone Aligned Prism (MCAP) and also with the available experimental results. NASA's unstructured grid suite of software TetrUSS and the automatic sourcing code AUTOSRC were used for base grid generation and flow solutions. The BG method has been evaluated on three wind tunnel models. Pressure signatures have been obtained up to two body lengths below a Gulfstream aircraft wind tunnel model. Good agreement with the wind tunnel results have been obtained for both on-track and off-track (up to 53 degrees) cases. On-track pressure signatures up to ten body lengths below a Straight Line Segmented Leading Edge (SLSLE) wind tunnel model have been extracted. Good agreement with the wind tunnel results have been obtained. Pressure signatures have been obtained at 1.5 body lengths below a Lockheed Martin aircraft wind tunnel model. Good agreement with the wind tunnel results have been obtained for both on-track and off-track (up to 40 degrees) cases. Grid sensitivity studies have been carried out to investigate any grid size related issues. Methods have been evaluated for fully turbulent, mixed laminar/turbulent and fully laminar flow conditions.

  19. Two-Dimensional Hydrodynamic Modeling and Analysis of the Proposed Channel Modifications and Grade Control Structure on the Blue River near Byram's Ford Industrial Park, Kansas City, Missouri

    USGS Publications Warehouse

    Huizinga, Richard J.

    2007-01-01

    The Blue River Channel Modification project being implemented by the U.S. Army Corps of Engineers (USACE) is intended to provide flood protection within the Blue River valley in the Kansas City, Mo., metropolitan area. In the latest phase of the project, concerns have arisen about preserving the Civil War historic area of Byram's Ford and the associated Big Blue Battlefield while providing flood protection for the Byram's Ford Industrial Park. In 1996, the USACE used a physical model built at the Waterways Experiment Station (WES) in Vicksburg, Miss., to examine the feasibility of a proposed grade control structure (GCS) that would be placed downstream from the historic river crossing of Byram's Ford to provide a subtle transition of flow from the natural channel to the modified channel. The U.S. Geological Survey (USGS), in cooperation with the USACE, modified an existing two-dimensional finite element surface-water model of the river between 63d Street and Blue Parkway (the 'original model'), used the modified model to simulate the existing (as of 2006) unimproved channel and the proposed channel modifications and GCS, and analyzed the results from the simulations and those from the WES physical model. Modifications were made to the original model to create a model that represents existing (2006) conditions between the north end of Swope Park immediately upstream from 63d Street and the upstream limit of channel improvement on the Blue River (the 'model of existing conditions'). The model of existing conditions was calibrated to two measured floods. The model of existing conditions also was modified to create a model that represents conditions along the same reach of the Blue River with proposed channel modifications and the proposed GCS (the 'model of proposed conditions'). The models of existing conditions and proposed conditions were used to simulate the 30-, 50-, and 100-year recurrence floods. The discharge from the calibration flood of May 15, 1990, also

  20. 25 CFR 292.21 - How will the Secretary evaluate a proposed gaming establishment?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false How will the Secretary evaluate a proposed gaming... ENTERPRISES GAMING ON TRUST LANDS ACQUIRED AFTER OCTOBER 17, 1988 Secretarial Determination and Governor's Concurrence Evaluation and Concurrence § 292.21 How will the Secretary evaluate a proposed...

  1. Ecological evaluation of proposed dredged material from Richmond Harbor

    SciTech Connect

    Pinza, M R; Ward, J A; Mayhew, H L; Word, J Q; Niyogi, D K; Kohn, N P

    1992-10-01

    During the summer of 1991, Battelle/Marine Sciences Laboratory (MSL) was contracted to conduct sampling and testing of sediments proposed for dredging of Richmond Harbor, California. The MSL collected sediment cores to a depth of [minus]40 ft MLLW ([minus]38 ft + 2 ft overdepth) from 28 (12-in. core) and 30 (4-in. core) stations. The sediment cores were allocated to six composite samples referred to as sediment treatments, which were then subjected to physical, chemical, toxicological, and bioaccumulation testing. Physical and chemical parameters included grain size, total organic carbon (TOC), total volatile solids (TVS), oil and grease, total petroleum hydrocarbons (TPH), polynuclear aromatic hydrocarbons (PAH), chlorinated pesticides, polychlorinated biphenyis (PCBs), priority pollutant metals, and butyltins. The results from the test treatments were compared to results from five reference treatments representative of potential in-bay and offshore disposal sites.

  2. Evaluation of proposed Skylab and SSP soap products.

    NASA Technical Reports Server (NTRS)

    Durfee, R. L.; Spurlock, J. M.; Whitmore, F. C.

    1973-01-01

    Four candidate cleansing agents evaluated in terms of potential hazards to crew members included two soaps (Neutrogena bar soap and Olive Leaf Liquid), one nonfoaming surfactant (Miranol JEM), and one laundry detergent (sodium dodecylbenzene sulfonate). None of the four exhibited adverse dermatological effects from skin patch tests or supported growth of potentially pathogenic microorganisms. Aqueous solutions of Neutrogena did support a mold species. Neutrogena and Miranol JEM were used in a simulated Skylab personal hygiene regimen with no adverse effects on skin or skin microflora. Based on our results, each of these agents appear to be a promising candidate material for the use intended.

  3. 78 FR 35942 - Proposed Collection; Comment Request: Palliative Care: Conversations Matter Evaluation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-14

    ... HUMAN SERVICES National Institutes of Health Proposed Collection; Comment Request: Palliative Care.... Proposed Collection Palliative Care: Conversations Matter Evaluation -0925--New--National Institute of... developed Palliative Care: Conversations Matter, a pediatric palliative care campaign to address...

  4. Evaluation of materials proposed for use in space flight

    NASA Technical Reports Server (NTRS)

    Duncan, W. C.

    1981-01-01

    The cutaneous primary irritancy and allergenicity potential of cotton shirts/fabrics treated with flame retardants were evaluated in order to establish their suitability for spacecraft crew use. Twenty-five volunteer human subjects were patch tested on the back utilizing standard methodology, with both treated and untreated cotton fabric. The fabric was treated with tetrakis (hydroxymethyl) phosphonium hydroxide and subsequently cured with gaseous ammonia. The final treatment comprised adding on dicyandiamine phosphoric acid. None of the individuals experienced primary irritant or allergic reactions attributable to the fabric during induction or challenge patch testing. Likewise, there were no reactions to treated or untreated fabric patches placed on ten subjects of the usage panel at the conclusion of the study.

  5. Evaluation of proposed Skylab and SSP soap products

    NASA Technical Reports Server (NTRS)

    Whitmore, F. C.; Durfee, R. L.; Spurlock, J. M.

    1973-01-01

    Three personal hygiene cleansing agents and one laundry detergent (sodium dodecyl benzene sulfonate), which are all candidates for use on long-duration space missions, were evaluated in terms of dermatological effects on human subjects and effects on microbiological species. None of the four materials exhibited adverse dermatological effects from either skin patch tests of two weeks duration or a simulated Skylab personal hygiene regimen of up to four weeks duration. No significant alterations in skin microflora during the use regimen were found. None of the four materials were found to serve as microbiological support media for the species tested, but a species of air-borne mold was observed to grow rapidly in a neutralized aqueous solution. None of the candidate agents was found to be strongly biocidal.

  6. Evaluation of Outlier Detection and Modification Methods Used in Flood Frequency Analysis

    NASA Astrophysics Data System (ADS)

    Senarath, S. U. S.

    2014-12-01

    Accurate and reliable information on flood frequency and magnitude is vital for the design of hydraulic structures and for floodplain mapping. The time-series data used for flood frequency analysis are obtained from both gauged systematic records and also historical floods. These time-series data sets, however, may include outliers. Outliers are defined as values that are much larger or smaller than most of the values in a given data set. Therefore, by definition, outliers include both very high and very low values. However, the main focus of this study is only on high outliers (hereafter referred to as simply outliers). The availability of a wide-array of tests and techniques makes the outlier detection and modification procedure anything but straightforward. The set of tests and techniques that is selected to detect and modify these outliers can have a direct impact on flood frequency and magnitude estimates. Many different approaches, based on the principles of hypothesis testing, are available for the detection of outliers. Several such methods are examined in detail in this study by using data from Southeast Europe. Outliers detected using these approaches can be eliminated, modified or disregarded (i.e., by treating them as non-outliers) prior to being used in flood frequency analyses. Eliminating or disregarding the outliers typically requires additional gauge- or event-specific information in order to be fully implemented. In the absence of such information, the practice of using modified outliers in flood frequency analysis provides the best compromise. Nevertheless, the effects of all three options on flood frequency and magnitude estimates are investigated to provide a more meaningful comparison. Flood magnitude-frequency estimates based on the log Pearson type 3 distribution are used in this study to evaluate the effect of outlier modification. The study findings have important implications for estimation of flood frequency and magnitude with time

  7. 77 FR 61446 - Proposed Revision Probabilistic Risk Assessment and Severe Accident Evaluation for New Reactors

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-09

    ... COMMISSION Proposed Revision Probabilistic Risk Assessment and Severe Accident Evaluation for New Reactors..., ``Probabilistic Risk Assessment and Severe Accident Evaluation for New Reactors.'' DATES: Submit comments by... No. ML081430087) concerning the review of probabilistic risk assessment (PRA) information and...

  8. Centres of Specialization & Program Suspensions/Modifications. Final Recommendations [and] Proposed Centres of Specialization & Other Academic Initiatives.

    ERIC Educational Resources Information Center

    Sir Sandford Fleming Coll., Peterborough (Ontario).

    In November 1995, Sir Sandford Fleming College, in Ontario, Canada, developed a proposal to establish centers of specialization, or clusters of related curricula or programs that are unique in a region, and to suspend or curtail existing programs due to funding shortages. Feedback was requested from the college community, with college-wide staff…

  9. Quantitative Evaluation of Peptide-Material Interactions by a Force Mapping Method: Guidelines for Surface Modification.

    PubMed

    Mochizuki, Masahito; Oguchi, Masahiro; Kim, Seong-Oh; Jackman, Joshua A; Ogawa, Tetsu; Lkhamsuren, Ganchimeg; Cho, Nam-Joon; Hayashi, Tomohiro

    2015-07-28

    Peptide coatings on material surfaces have demonstrated wide application across materials science and biotechnology, facilitating the development of nanobio interfaces through surface modification. A guiding motivation in the field is to engineer peptides with a high and selective binding affinity to target materials. Herein, we introduce a quantitative force mapping method in order to evaluate the binding affinity of peptides to various hydrophilic oxide materials by atomic force microscopy (AFM). Statistical analysis of adhesion forces and probabilities obtained on substrates with a materials contrast enabled us to simultaneously compare the peptide binding affinity to different materials. On the basis of the experimental results and corresponding theoretical analysis, we discuss the role of various interfacial forces in modulating the strength of peptide attachment to hydrophilic oxide solid supports as well as to gold. The results emphasize the precision and robustness of our approach to evaluating the adhesion strength of peptides to solid supports, thereby offering guidelines to improve the design and fabrication of peptide-coated materials. PMID:26125092

  10. 10 CFR 745.123 - Early termination of research support: Evaluation of applications and proposals.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false Early termination of research support: Evaluation of applications and proposals. 745.123 Section 745.123 Energy DEPARTMENT OF ENERGY PROTECTION OF HUMAN SUBJECTS § 745.123 Early termination of research support: Evaluation of applications and proposals. (a)...

  11. 10 CFR 745.123 - Early termination of research support: Evaluation of applications and proposals.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Early termination of research support: Evaluation of applications and proposals. 745.123 Section 745.123 Energy DEPARTMENT OF ENERGY PROTECTION OF HUMAN SUBJECTS § 745.123 Early termination of research support: Evaluation of applications and proposals. (a)...

  12. 10 CFR 745.123 - Early termination of research support: Evaluation of applications and proposals.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Early termination of research support: Evaluation of applications and proposals. 745.123 Section 745.123 Energy DEPARTMENT OF ENERGY PROTECTION OF HUMAN SUBJECTS § 745.123 Early termination of research support: Evaluation of applications and proposals. (a)...

  13. 43 CFR 404.22 - How will Reclamation evaluate my full proposal?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 1 2011-10-01 2011-10-01 false How will Reclamation evaluate my full proposal? 404.22 Section 404.22 Public Lands: Interior Regulations Relating to Public Lands BUREAU OF RECLAMATION, DEPARTMENT OF THE INTERIOR RECLAMATION RURAL WATER SUPPLY PROGRAM Overview § 404.22 How will Reclamation evaluate my full proposal?...

  14. 43 CFR 404.22 - How will Reclamation evaluate my full proposal?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 1 2014-10-01 2014-10-01 false How will Reclamation evaluate my full proposal? 404.22 Section 404.22 Public Lands: Interior Regulations Relating to Public Lands BUREAU OF RECLAMATION, DEPARTMENT OF THE INTERIOR RECLAMATION RURAL WATER SUPPLY PROGRAM Overview § 404.22 How will Reclamation evaluate my full proposal?...

  15. 2 CFR 176.110 - Evaluating proposals of foreign iron, steel, and/or manufactured goods.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 2 Grants and Agreements 1 2010-01-01 2010-01-01 false Evaluating proposals of foreign iron, steel... Evaluating proposals of foreign iron, steel, and/or manufactured goods. (a) If the award official receives a request for an exception based on the cost of certain domestic iron, steel, and/or manufactured...

  16. 2 CFR 176.110 - Evaluating proposals of foreign iron, steel, and/or manufactured goods.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 2 Grants and Agreements 1 2011-01-01 2011-01-01 false Evaluating proposals of foreign iron, steel... American Recovery and Reinvestment Act of 2009 § 176.110 Evaluating proposals of foreign iron, steel, and... cost of certain domestic iron, steel, and/or manufactured goods being unreasonable, in accordance...

  17. 10 CFR 745.123 - Early termination of research support: Evaluation of applications and proposals.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Early termination of research support: Evaluation of applications and proposals. 745.123 Section 745.123 Energy DEPARTMENT OF ENERGY PROTECTION OF HUMAN SUBJECTS § 745.123 Early termination of research support: Evaluation of applications and proposals. (a)...

  18. 32 CFR 219.123 - Early termination of research support: Evaluation of applications and proposals.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 2 2012-07-01 2012-07-01 false Early termination of research support: Evaluation of applications and proposals. 219.123 Section 219.123 National Defense Department of Defense....123 Early termination of research support: Evaluation of applications and proposals. (a)...

  19. 10 CFR 745.123 - Early termination of research support: Evaluation of applications and proposals.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false Early termination of research support: Evaluation of applications and proposals. 745.123 Section 745.123 Energy DEPARTMENT OF ENERGY PROTECTION OF HUMAN SUBJECTS § 745.123 Early termination of research support: Evaluation of applications and proposals. (a)...

  20. 23 CFR Appendix D to Subpart A of... - Guidance Criteria for Evaluating Requests for Modifications to the National Highway System

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 23 Highways 1 2014-04-01 2014-04-01 false Guidance Criteria for Evaluating Requests for Modifications to the National Highway System D Appendix D to Subpart A of Part 470 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PLANNING AND RESEARCH HIGHWAY SYSTEMS Federal-aid Highway Systems Pt. 470, Subpt. A, App. D Appendix D...

  1. Evaluation of exercise-respiratory system modifications and preliminary respiratory-circulatory system integration scheme

    NASA Technical Reports Server (NTRS)

    Gallagher, R. R.

    1974-01-01

    The respiratory control system, functioning as an independent system, is presented with modifications of the exercise subroutine. These modifications illustrate an improved control of ventilation rates and arterial and compartmental gas tensions. A very elementary approach to describing the interactions of the respiratory and circulatory system is presented.

  2. Modification of integrated partial payload lifting assembly

    NASA Technical Reports Server (NTRS)

    Groah, Melodie; Haddock, Michael; Woodworth, Warren

    1986-01-01

    The Integrated Partial Payload Lifting Assembly (IPPLA) is currently used to transport and load experimental payloads into the cargo bay of the Space Shuttle. It is unable to carry the astronaut/passenger tunnel without a structural modification. The purpose of this design is to create a removalbe modification that will allow the IPPLA to lift and carry the passenger tunnel. Modifications evaluated were full-length insert beams which would extend through the existing strongback arms. These beam proposals were eliminated because of high cost and weight. Other proposals evaluated were attachments of cantilever beams to the existing strongback areas. The cantilever proposals reduced cost and weight compared to the full-length modifications. A third method evaluated was to simply make modifications to one side of the IPPLA therefore reducing the materials of the cantilever proposals by 40 percent. The design of the modification selected was completed with two channel beams jointly welded to a centered steel plate. The extension arm modification is inserted into the existing strongback channel beams and bolted into place. Two extension arms are added to one side of the IPPLA to provide the extra length needed to accommodate the passenger tunnel. The center counterbalance will then be offset about 20 inches to center gravity and therefore maintain horizontal status. The extension arm modification was selected because of minimum cost, low weight, and minimal installation time.

  3. Enzymatic modification of palmarosa essential oil: chemical analysis and olfactory evaluation of acylated products.

    PubMed

    Ramilijaona, Jade; Raynaud, Elsa; Bouhlel, Charfeddine; Sarrazin, Elise; Fernandez, Xavier; Antoniotti, Sylvain

    2013-12-01

    We have developed an enzymatic protocol to modify the composition of palmarosa essential oil by acylation of its alcohol components by three different acyl donors at various rates. The resulting modified products were characterized by qualitative and quantitative analyses by gas chromatography, and their olfactory properties were evaluated by professional perfumers. We showed that our protocol resulted in two types of modifications of the olfactory properties. The first and most obvious effect observed was the decrease of the alcohol content, with the concomitant increase of the corresponding esters, along with their fruity notes (pear, most notably). The second and less obvious effect was the expression of notes from minor components ((E)-β-ocimene, linalool, β-caryophyllene, and farnesene), originally masked by the sweet-floral-rose odor of geraniol, present in 70% in the palmarosa essential oil used, and emergence of citrus, green, spicy and clove characters in the modified products. This methodology might be considered in the future as a sustainable route to new natural ingredients for the perfumer. PMID:24327448

  4. Proposed modifications to the RCRA post-closure permit for the Upper East Fork Poplar Creek Hydrogeologic Regime at the U.S. Department of Energy Y-12 Plant, Oak Ridge, Tennessee

    SciTech Connect

    1997-05-01

    This report presents proposed modifications to the Resource Conservation and Recovery Act (RCRA) Post-Closure Permit (PCP) for the Upper East Fork Poplar Creek Hydrogeologic Regime (permit number TNHW-088, EPA ID No. TN3 89 009 0001). The modifications are proposed to: (1) revise the current text for two of the Permit Conditions included in Permit Section II - General Facility Conditions, and (2) update the PCP with revised versions of the Y-12 Plant Groundwater Protection Program (GWPP) technical field procedures included in several of the Permit Attachments. The updated field procedures and editorial revisions are Class 1 permit modifications, as specified in Title 40, Code of Federal Regulations (CFR) {section}270.42; Appendix I - Classification of Permit Modifications. These modifications are summarized below.

  5. Proposed modification of an instrumented TRIGA fuel element so that it may be handled with a standard TRIGA fuel handling tool

    SciTech Connect

    Doane, Harry J.

    1992-07-01

    Instrumented fuel elements whose thermocouples are no longer functional are still a useful source of reactor fuel. Their usefulness is hampered somewhat by the extension tubing that must extend above water level to keep the thermocouple extension leads dry and to keep pool water from interacting with the gas tight lead seal which is made below the lower coupling in the extension tubing. This facility proposes to modify an instrumented TRIGA fuel element by removing the extension tubing at the lower coupling and attaching to it a top end fixture that is normally supplied with a standard TRIGA fuel element. This would then allow movement of the modified fuel element with a standard TRIGA fuel handling tool. This paper will present the considerations involved in performing this modification and the presenter will solicit any useful information that might be contributed by attendees of the TRIGA Owners' Conference. (author)

  6. 10 CFR 501.102 - OFE evaluation of the record, decision and order for modification or rescission of a rule or order.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false OFE evaluation of the record, decision and order for modification or rescission of a rule or order. 501.102 Section 501.102 Energy DEPARTMENT OF ENERGY (CONTINUED) ALTERNATE FUELS ADMINISTRATIVE PROCEDURES AND SANCTIONS Requests for Modification or Rescission of a Rule or Order § 501.102 OFE evaluation...

  7. Curriculum content and evaluation of resident competency in anatomic pathology: a proposal.

    PubMed

    2003-11-01

    In response to new requirements laid down by the Accreditation Council for Graduate Medical Education (ACGME), the Association of Directors of Anatomic and Surgical Pathology (ADASP) has developed a detailed curriculum, as well as guidelines for assessing competence, for resident training in anatomic pathology, focused principally on the core competencies in patient care and medical knowledge. The proposed curriculum described herein is offered as a template for potential use (with or without any necessary local modifications) by pathology training programs. Other areas of competency (eg, practice-based learning, interpersonal/communication skills, professionalism, and systems-based practice) are covered elsewhere on the Program Directors in Pathology and ACGME websites. PMID:14652807

  8. 76 FR 63924 - Agency Information Collection Activities; Proposed Collection; Comment Request; the Evaluation of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-14

    ... appropriate, and other forms of information technology. The Aging and Disability Resource Center (ADRC... HUMAN SERVICES Administration on Aging Agency Information Collection Activities; Proposed Collection; Comment Request; the Evaluation of the Aging and Disability Resource Center Program AGENCY:...

  9. 48 CFR 2052.215-79 - Contract award and evaluation of proposals.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... cost analysis is performed on each cost proposal. To provide a common base for evaluation of cost... specified in paragraph * below. These factors are listed in their relative order of importance. (b)...

  10. 75 FR 54295 - Agency Information Collection Activities: Proposed Collection; Comment Request-Evaluation of SNAP...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-07

    ...; ] DEPARTMENT OF AGRICULTURE Food and Nutrition Service Agency Information Collection Activities: Proposed Collection; Comment Request--Evaluation of SNAP Nutrition Education Practices Study AGENCY: Food and Nutrition Service (FNS), USDA. ACTION: Notice. SUMMARY: In accordance with the Paperwork Reduction Act...

  11. 77 FR 36292 - Proposed Collection, Comments Requested: FBI National Academy Level III Evaluation; FBI National...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-18

    ... Federal Bureau of Investigation Proposed Collection, Comments Requested: FBI National Academy Level III... Department of Justice (DOJ), Federal Bureau of Investigation (FBI), Training Division's Office of Technology... Laleatha B. Goode, Management and Program Analyst for the Evaluation Program, Federal Bureau......

  12. 77 FR 32084 - Notice of Proposed Information Collection Requests; Office of Planning, Evaluation and Policy...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-31

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF EDUCATION Notice of Proposed Information Collection Requests; Office of Planning, Evaluation and Policy Development; EDFacts Collection of Elementary and Secondary Education Act of 1965 (ESEA) Flexibility Data SUMMARY:...

  13. 77 FR 35665 - Notice of Proposed Information Collection Requests; Office of Planning, Evaluation and Policy...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-14

    ... Notice of Proposed Information Collection Requests; Office of Planning, Evaluation and Policy Development..., 400 Maryland Avenue SW., LBJ, Washington, DC 20202-4537. Copies of the proposed information collection... and by clicking on link number 04869. When you access the information collection, click on...

  14. A Proposal for a New Teacher Evaluation Process for the Delsea Regional School District

    ERIC Educational Resources Information Center

    Gravenor, Piera N.

    2011-01-01

    This executive position paper proposes recommendations for changes to the teacher evaluation policy and practice in the Delsea Regional School District. These recommendations are based upon best practices and evolving federal and state mandates in this area. A summarization of the current practice is provided along with proposed alternatives and…

  15. Economic evaluation: Concepts, selected studies, system costs, and a proposed program

    NASA Technical Reports Server (NTRS)

    Osterhoudt, F. H. (Principal Investigator)

    1979-01-01

    The more usual approaches to valuing crop information are reviewed and an integrated approach is recommended. Problems associated with implementation are examined. What has already been accomplished in the economic evaluation of LACIE-type information is reported including various studies of benefits. The costs of the existing and proposed systems are considered. A method and approach is proposed for further studies.

  16. 2 CFR 176.110 - Evaluating proposals of foreign iron, steel, and/or manufactured goods.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 2 Grants and Agreements 1 2012-01-01 2012-01-01 false Evaluating proposals of foreign iron, steel... proposals of foreign iron, steel, and/or manufactured goods. (a) If the award official receives a request for an exception based on the cost of certain domestic iron, steel, and/or manufactured goods...

  17. 2 CFR 176.110 - Evaluating proposals of foreign iron, steel, and/or manufactured goods.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 2 Grants and Agreements 1 2013-01-01 2013-01-01 false Evaluating proposals of foreign iron, steel... proposals of foreign iron, steel, and/or manufactured goods. (a) If the award official receives a request for an exception based on the cost of certain domestic iron, steel, and/or manufactured goods...

  18. 16 CFR 1028.123 - Early termination of research support: Evaluation of applications and proposals.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... terms of this policy. (b) In making decisions about supporting or approving applications or proposals... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Early termination of research support: Evaluation of applications and proposals. 1028.123 Section 1028.123 Commercial Practices CONSUMER...

  19. Synthesis and biological evaluation of peptide-conjugated phthalocyanine photosensitizers with highly hydrophilic modifications.

    PubMed

    Li, Fu; Liu, Qian; Liang, Zhenzhen; Wang, Jin; Pang, Mingpei; Huang, Weiqiang; Wu, Wenjie; Hong, Zhangyong

    2016-04-01

    The selectivity of targeted photosensitizer delivery is a constant challenge for photodynamic therapy (PDT). Herein, with the aim of optimizing the affinity, selectivity and activity of peptide-conjugated photosensitizers for PDT therapy and fluorescence imaging, we designed a solid-phase strategy for the efficient synthesis of peptide-phthalocyanine (Pc) conjugates with two types of highly hydrophilic modifications to the Pc rings. The peptide conjugation clearly increased the photodynamic efficacy and selectivity of Pcs against cancer cells with different receptor expression levels. A highly hydrophilic modification to the Pc rings can block non-specific interactions between the Pcs and biological molecules while minimally influencing peptide ligand affinity with target receptors. Compared with the triethyleneglycol monomethyl ether group modification, the glycerol group modification exhibited a stronger capability to decrease the Pc aggregation tendency in aqueous medium, reduce non-specific binding and non-specific, light-induced cytotoxicity towards cells with low receptor expression in vitro; increased targeting selectivity was observed in the in vivo distribution experiments via the obvious reduction of background signals. Highly hydrophilic modifications to the Pc rings may be very useful for improving targeting selectivity for PDT with the construction of peptide-conjugated photosensitizers. PMID:26956169

  20. Social Security reform: evaluating current proposals. Latest results of the EBRI-SSASIM2 policy simulation model.

    PubMed

    Copeland, C; VanDerhei, J; Salisbury, D L

    1999-06-01

    The present Social Security program has been shown to be financially unsustainable in the future without modification to the current program. The purpose of this Issue Brief, EBRI's fourth in a series on Social Security reform, is threefold: to illustrate new features of the EBRI-SSASIM2 policy simulation model not available in earlier EBRI publications, to expand quantitative analysis to specific proposals, and to evaluate the uncertainty involved in proposals that rely on equity investment. This analysis compares the Gregg/Breaux-Kolbe/Stenholm (GB-KS) and Moynihan/Kerrey proposals with three generic or "traditional" reforms: increasing taxes, reducing benefits, and/or increasing the retirement age. Both proposals would create individual accounts by "carving out" funds from current Social Security payroll taxes. This analysis also examines other proposed changes that would "add on" to existing Social Security funds through the use of general revenue transfers and/or investment in the equities market. President Clinton has proposed a general revenue transfer and the collective investment of some of the OASDI trust fund assets in equities. Reps. Archer and Shaw have proposed a general revenue tax credit to establish individual accounts that would be invested partially in the equities markets. When comparing Social Security reform proposals that would specifically alter benefit levels, the Moynihan/Kerrey bill compares quite favorably with the other proposals in both benefit levels and payback ratios, when individuals elect to use the individual account option. In contrast, the GB-KS bills do not compare quite as favorably for their benefit levels, but do compare favorably in terms of payback ratios. An important comparison in these bills is the administrative costs of managing the individual accounts, since benefits can be lowered by up to 23 percent when going from the assumed low to high administrative costs. Moreover, allowing individuals to decide whether to

  1. In Pursuit of Social Betterment: A Proposal to Evaluate the Da Vinci Learning Model

    ERIC Educational Resources Information Center

    Henry, Gary T.

    2005-01-01

    The author presents a proposal that is roughly based on a contingency-based theory of evaluation developed in his book, "Evaluation: An Integrated Framework for Understanding, Guiding, and Improving Policies and Programs" (Mark, Henry, and Julnes, 2000). He and his coauthors stated in this book that social betterment was the ultimate goal of…

  2. 77 FR 75251 - 60-Day Notice of Proposed Information Collection: Gilman Evaluation Survey

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-19

    ...-based to ease any burden on the participant. The survey will be distributed and responses received... Notice of Proposed Information Collection: Gilman Evaluation Survey ACTION: Notice of request for public...: Gilman Evaluation Survey. OMB Control Number: None. Type of Request: New Collection. Originating...

  3. 78 FR 15801 - 30-Day Notice of Proposed Information Collection: Gilman Evaluation Survey

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-12

    ... Notice of Proposed Information Collection: Gilman Evaluation Survey ACTION: Notice of request for public... halemj2@state.gov . SUPPLEMENTARY INFORMATION: Title of Information Collection: Gilman Evaluation Survey... Responses: 2,474. Average Time per Response: 25 minutes. Total Estimated Burden Time: 1,031 hours....

  4. 76 FR 27380 - Proposed Information Collection (Report of Medical Examination for Disability Evaluation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-11

    ... AFFAIRS Proposed Information Collection (Report of Medical Examination for Disability Evaluation); Comment.... Title: Report of Medical Examination for Disability Evaluation, VA Form 21-2545. OMB Control Number... solicits comments for information needed from claimants prior to undergoing a VA medical examination...

  5. 77 FR 66649 - Proposed Revision to Probabilistic Risk Assessment and Severe Accident Evaluation for New Reactors

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-06

    ... COMMISSION Proposed Revision to Probabilistic Risk Assessment and Severe Accident Evaluation for New Reactors... comment period. SUMMARY: On October 9, 2012 (77 FR 61446), the U.S. Nuclear Regulatory Commission (NRC or...), Section 19.0 ``Probabilistic Risk Assessment and Severe Accident Evaluation for New Reactors.'' The NRC...

  6. 76 FR 1129 - Agency Information Collection Activities: Proposed Collection; Comment Request-Evaluation of the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-07

    ... food security. In addition to impact measures, the evaluation will document the process and challenges... Food and Nutrition Service Agency Information Collection Activities: Proposed Collection; Comment Request--Evaluation of the Impact of the Summer Food Service Programs Enhancement Demonstrations on...

  7. 77 FR 37070 - Proposed Collection of Information for the Evaluation of the Self-Employment Training...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-20

    ... Employment and Training Administration Proposed Collection of Information for the Evaluation of the Self... visit data collection, and case study interviews are for an evaluation of the Self-Employment Training... providing dislocated workers access to self-employment training and counseling services increases...

  8. 75 FR 9279 - Proposed Information Collection (Survey of Satisfaction With the Disability Evaluation System...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-01

    ... AFFAIRS Proposed Information Collection (Survey of Satisfaction With the Disability Evaluation System (DES... of Satisfaction with the Disability Evaluation System (DES). OMB Control Number: 2900-New (DES). Type... and, if necessary, revise the way the DES Pilot is conducted in an effort to raise customer...

  9. 45 CFR 690.123 - Early termination of research support: Evaluation of applications and proposals.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Early termination of research support: Evaluation... of research support: Evaluation of applications and proposals. (a) The department or agency head may... prescribed in applicable program requirements, when the department or agency head finds an institution...

  10. 40 CFR 26.123 - Early termination of research support: Evaluation of applications and proposals.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Early termination of research support: Evaluation of applications and proposals. 26.123 Section 26.123 Protection of Environment ENVIRONMENTAL... Research Conducted or Supported by EPA § 26.123 Early termination of research support: Evaluation...

  11. 7 CFR 1c.123 - Early termination of research support: Evaluation of applications and proposals.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 1 2012-01-01 2012-01-01 false Early termination of research support: Evaluation of applications and proposals. 1c.123 Section 1c.123 Agriculture Office of the Secretary of Agriculture PROTECTION OF HUMAN SUBJECTS § 1c.123 Early termination of research support: Evaluation of applications...

  12. 22 CFR 225.123 - Early termination of research support: Evaluation of applications and proposals.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Early termination of research support: Evaluation of applications and proposals. 225.123 Section 225.123 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT PROTECTION OF HUMAN SUBJECTS § 225.123 Early termination of research support: Evaluation...

  13. 22 CFR 225.123 - Early termination of research support: Evaluation of applications and proposals.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Early termination of research support: Evaluation of applications and proposals. 225.123 Section 225.123 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT PROTECTION OF HUMAN SUBJECTS § 225.123 Early termination of research support: Evaluation...

  14. 49 CFR 11.123 - Early termination of research support: Evaluation of applications and proposals.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 1 2014-10-01 2014-10-01 false Early termination of research support: Evaluation of applications and proposals. 11.123 Section 11.123 Transportation Office of the Secretary of Transportation PROTECTION OF HUMAN SUBJECTS § 11.123 Early termination of research support: Evaluation...

  15. 22 CFR 225.123 - Early termination of research support: Evaluation of applications and proposals.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Early termination of research support: Evaluation of applications and proposals. 225.123 Section 225.123 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT PROTECTION OF HUMAN SUBJECTS § 225.123 Early termination of research support: Evaluation...

  16. 45 CFR 690.123 - Early termination of research support: Evaluation of applications and proposals.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 3 2011-10-01 2011-10-01 false Early termination of research support: Evaluation... Welfare (Continued) NATIONAL SCIENCE FOUNDATION PROTECTION OF HUMAN SUBJECTS § 690.123 Early termination of research support: Evaluation of applications and proposals. (a) The department or agency head...

  17. NASA RECON: Course development, administration, and evaluation. A research and development proposal

    NASA Technical Reports Server (NTRS)

    Dominick, Wayne D. (Editor); Roquemore, Leroy

    1984-01-01

    This proposal addresses the development, administration, and evaluation of a set of transportable, college-level courses to educate science and engineering students in the effective use of automated scientific and technical information storage and retrieval systems, and, in particular, in the use of the NASA RECON system. Chapter 1 presents a brief introduction. Chapter 2 identifies general and specific objectives, i.e., needs analysis, course development, course administration, and course evaluation. Chapter 3 proposes the methodology to be used in successfully accomplishing these objectives. Chapter 4 highlights expected results and product deliverables, and Chapter 5 presents the project evaluation plan to be followed. Chapter 6 is a brief overview of the institutional resources available at the proposing institutions, i.e., at the University of Southwestern Louisiana and at Southern University to support the project. Chapter 7 proposes a budget, time schedule, and management plan. Chapter 8 is a summary of the foregoing.

  18. A Numerical model to evaluate proposed ground-water allocations in southwest Kansas

    USGS Publications Warehouse

    Jorgensen, D.G.; Grubb, H.F.; Baker, C.H.; Hilmes, G.E.; Jenkins, E.D.

    1982-01-01

    A computer model was developed to assist the Southwest Kansas Groundwater Management District No. 3 in the evaluation of applications to appropriate ground water. The model calculated the drawdown due from a proposed well at all existing wells in the section of the proposed well and at all wells in the adjacent eight sections. The depletion expected in the 9-square-mile area due to all existing wells and the proposed well is computed and compared with allowable limits defined by the management district. An optional program permits the evaluation of allowable depletion for one or more townships. All options are designed to run interactively, thus allowing for immediate evaluation of proposed ground-water withdrawals. (USGS)

  19. Evaluation of heterogeneous metal-organic framework organocatalysts prepared by postsynthetic modification.

    PubMed

    Garibay, Sergio J; Wang, Zhenqiang; Cohen, Seth M

    2010-09-01

    A metal-organic framework (MOF) containing 2-amino-1,4-benzenedicarboxylate (NH(2)-BDC) as a building block is shown to undergo chemical modification with a set of cyclic anhydrides. The modification of the aluminum-based MOF known as MIL-53(Al)-NH(2) (MIL = Material Institut Lavoisier) by these reagents is demonstrated by using a variety of methods, including NMR and electrospray ionization mass spectrometry (ESI-MS), and the structural integrity of the modified MOFs has been confirmed by thermal gravimetric analysis (TGA) and powder X-ray diffraction (PXRD). Reaction with these cyclic anhydrides produces MOFs that display carboxylic acid functional groups within their pores. Furthermore, it is shown that maleic acid functionalized MIL-53(Al)-AMMal can act as a Brønsted acid catalyst and facilitate the methanolysis of several small epoxides. Experiments show that MIL-53(Al)-AMMal acts in a heterogeneous manner and is recyclable with consistent activity over at least three catalytic cycles. The findings presented here demonstrate several important features of covalent postsynthetic modification (PSM) on MOFs, including (1) facile introduction of catalytic functionality using simple organic reagents (e.g., anhydrides); (2) the ability to utilize and recycle organocatalytic MOFs; (3) control of catalytic activity through choice of functional group. The findings clearly illustrate that covalent postsynthetic modification represents a powerful means to access new MOF compounds that serve as organocatalytic materials. PMID:20698561

  20. Formative Evaluation of Project "TEAM" (Teens Making Environment and Activity Modifications)

    ERIC Educational Resources Information Center

    Kramer, Jessica M.; Roemer, Kristin; Liljenquist, Kendra; Shin, Julia; Hart, Stacy

    2014-01-01

    Research documents the negative impact of physical and social environmental barriers on engagement in school, work, and the community for youth with intellectual and /or developmental disabilities (IDD). Project "TEAM" (Teens making Environment and Activity Modifications) was designed to teach youth to systematically identify…

  1. Evaluation of Heterogeneous Metal-Organic Framework Organocatalysts Prepared by Postsynthetic Modification

    PubMed Central

    Garibay, Sergio J.; Wang, Zhenqiang; Cohen, Seth M.

    2010-01-01

    A metal-organic framework (MOF) containing 2-amino-1,4-benzenedicarboxylate (NH2-BDC) as a building block is shown to undergo chemical modification with a set of cyclic anhydrides. The modification of the aluminum-based MOF known as MIL-53(Al)-NH2 (MIL = Matérial Institut Lavoisier) by these reagents is demonstrated by using a variety of methods, including NMR and ESI-MS, and the structural integrity of the modified MOFs has been confirmed by TGA, PXRD, and gas sorption analysis. Reaction with these cyclic anhydrides produces MOFs that display carboxylic acid functional groups within their pores. Furthermore, it is shown that maleic acid functionalized MIL-53(Al)-AMMal can act as a Brønsted acid catalyst and facilitate the methanolysis of several small epoxides. Experiments show that MIL-53(Al)-AMMal acts in a heterogeneous manner and is recyclable with consistent activity over at least three catalytic cycles. The findings presented here demonstrate several important features of covalent postsynthetic modification (PSM) on MOFs, including: 1) facile introduction of catalytic functionality using simple organic reagents (e.g. anhydrides); 2) the ability to utilize and recycle organocatalytic MOFs; 3) control of catalytic activity through choice of functional group. The findings clearly illustrate that covalent postsynthetic modification represents a powerful means to access new MOF compounds that serve as organocatalytic materials. PMID:20698561

  2. Evaluation of a Cooperative Extension Curriculum in Florida: Food Modification for Special Needs

    ERIC Educational Resources Information Center

    Dahl, Wendy J.; Ford, Amanda L.; Radford, Allyson; Gal, Nancy J.

    2016-01-01

    State and national surveys of adult family care homes identified a strong need for education on texture-modified food preparation and the nutritional needs of older adults. An Extension curriculum, Food Modification for Special Needs, was developed to provide an overview of chewing and swallowing problems, food texture, pureed food preparation,…

  3. EVALUATION OF SENSORY SYSTEM FUNCTION USING REFLEX MODIFICATION OF THE STARTLE RESPONSE

    EPA Science Inventory

    Methods to measure damage to sensory systems following toxicant exposure vary from rapid and subjective tests (e.g., pinna reflex) to time-consuming and objective tests (e.g., psychophysical tests). eflex modification of the startle response represents an alternative technique in...

  4. Evaluation of the Cask Transportation Facility Modifications (CTFM) compliance to DOE order 6430.1A Project A.5 and A.6

    SciTech Connect

    ARD, K.E.

    2000-04-24

    This report was prepared to evaluate the compliance of CTFM to DOE Order 6430.1A. This document presents the results of an evaluation that was performed to assess compliance of the K West (KW) Cask Transportation Facility Modifications (CTFM) designs against applicable requirements of Department of Energy (DOE) Order 6430.1 A, General Design Criteria. This evaluation was grouped under two categories described as Cask Loadout System (CLS) and Cranes/Other Modifications.

  5. Evaluation in Cross-Cultural Contexts: Proposing a Framework for International Education and Training Project Evaluations.

    ERIC Educational Resources Information Center

    bin Yahya, Ismail; And Others

    This paper focuses on the need for increased sensitivity and responsiveness in international education and training project evaluations, particularly those in Third World countries. A conceptual-theoretical framework for designing and developing models appropriate for evaluating education and training projects in non-Western cultures is presented.…

  6. Calendar year 1994 groundwater quality report for the Bear Creek hydrogeologic regime, Y-12 Plant, Oak Ridge, Tennessee. 1994 Groundwater quality data interpretations and proposed program modifications

    SciTech Connect

    1995-10-01

    This groundwater quality report (GWQR) contains an evaluation of the groundwater quality data obtained during the 1994 calendar year (CY) at several hazardous and non-hazardous waste management facilities at the US Department of Energy (DOE) Y-12 Plant. These sites lie in Bear Creek Valley (BCV) west of the Y-12 Plant within the boundaries of the Bear Creek Hydrogeologic Regime which is one of three hydrogeologic regimes defined for the purposes of groundwater quality monitoring. The Environmental Management Department manages the groundwater monitoring activities under the auspices of the Y-12 Plant Groundwater Protection Program (GWPP). The purpose of the GWPP is to characterize the hydrogeology and to monitor groundwater quality at the Y-12 Plant and surrounding area to protect local groundwater resources. The annual GWQR for the Bear Creek Regime is completed in two parts. Part 1 consists primarily of data appendices and serves as a reference for the groundwater quality data obtained each CY. Part 2 (this report) contains an evaluation of the data with respect to regime-wide groundwater quality, summarizes the status and findings of ongoing hydrogeologic studies, describes changes in monitoring priorities, and presents planned modifications to the groundwater sampling and analysis activities.

  7. A prototype decision aid for evaluating and selecting R&D proposals

    SciTech Connect

    Al-Ayat, R.A.; Lamont, A.; Sicherman, A.

    1992-05-01

    This report describes a prototype decision aid which has been developed to assist the Institutional Research and Development (IR&D) Committee in selecting proposals for funding. This tool was requested to help address the following concerns about the IR&D proposal selection process: Some good proposals might be overlooked simply because no one on the Committee advocates them forcefully. The process takes a lot of time. The final portfolio of proposals selected may not maximize the long-run benefits to the Laboratory. These concerns stem from the observation that there is no formal framework for making distinctions between proposals, or weighing and comparing those distinctions. It was felt that the process could be improved by a framework that: Provides explicit descriptors that Committee members can use to evaluate and compare different features of proposals. Encourages the Committee to use a uniform, systematic scheme for evaluating the proposals. Helps the Committee focus more quickly on the issues that are truly relevant for distinguishing between proposals.

  8. Calendar year 1993 groundwater quality report for the Chestnut Ridge Hydrogeologic Regime Y-12 Plant, Oak Ridge, Tennessee. 1993 Groundwater quality data interpretations and proposed program modifications

    SciTech Connect

    1994-09-01

    This groundwater quality report (GWQR) contains an evaluation of the groundwater quality data obtained during the 1993 calendar year (CY) at several hazardous and non-hazardous waste management facilities associated with the US DOE Y-12 Plant located on the DOE Oak Ridge Reservation (ORR) southeast of Oak Ridge, Tennessee. The groundwater quality data are presented in Part 1 of the GWQR submitted by Martin Marietta Energy Systems, Inc. to the Tennessee Department of Environment and Conservation (TDEC) in February 1994. Groundwater quality data evaluated in this report were obtained at several hazardous and non-hazardous waste management sites located within the Chestnut Ridge Hydrogeologic Regime (Chestnut Ridge Regime). The Chestnut Ridge Regime encompasses a section of Chestnut Ridge south of the Y-12 Plant and is one of three hydrogeologic regimes defined for the purposes of groundwater quality monitoring at the plant. The Environmental Management Department of the Y-12 Plant Health, Safety, Environment, and Accountability Organization manages the groundwater monitoring activities in each regime as part of the Y-12 Plant Groundwater Protection Program (GWPP). The annual GWQR for the Chestnut Ridge Regime is completed in two parts. Part 1 consists primarily of data appendices and serves as a reference for the groundwater quality data obtained each CY under the lead of the Y-12 Plant GWPP. Because it contains information needed to comply with Resource Conservation and Recovery Act (RCRA) interim status assessment monitoring and reporting requirements, the Part 1 GWQR is submitted to the TDEC by the RCRA reporting deadline (March 1 of the following CY). Part 2 (this report) contains an evaluation of the data with respect to regime-wide groundwater quality, presents the findings and status of ongoing hydrogeologic studies, describes changes in monitoring priorities, and presents planned modifications to the groundwater sampling and analysis activities.

  9. Managing proposals and evaluations of updates to medical knowledge: theory and applications.

    PubMed

    Anselma, Luca; Bottrighi, Alessio; Montani, Stefania; Terenziani, Paolo

    2013-04-01

    The process of keeping up-to-date the medical knowledge stored in relational databases is of paramount importance. Since quality and reliability of medical knowledge are essential, in many cases physicians' proposals of updates must undergo experts' evaluation before possibly becoming effective. However, until now no theoretical framework has been provided in order to cope with this phenomenon in a principled and non-ad hoc way. Indeed, such a framework is important not only in the medical domain, but in all Wikipedia-like contexts in which evaluation of update proposals is required. In this paper we propose GPVM (General Proposal Vetting Model), a general model to cope with update proposal⧹evaluation in relational databases. GPVM extends the current theory of temporal relational databases and, in particular, BCDM - Bitemporal Conceptual Data Model - "consensus" model, providing a new data model, new operations to propose and accept⧹reject updates, and new algebraic operators to query proposals. The properties of GPVM are also studied. In particular, GPVM is a consistent extension of BCDM and it is reducible to it. These properties ensure consistency with most relational temporal database frameworks, facilitating implementation on top of current frameworks and interoperability with previous approaches. PMID:23380684

  10. Evaluation of dredged material proposed for ocean disposal from Buttermilk Channel, New York

    SciTech Connect

    Gardiner, W.W.; Barrows, E.S.; Antrim, L.D; Gruendell, B.D.; Word, J.Q.; Tokos, J.J.S.

    1996-08-01

    Buttermilk Channel was one of seven waterways that was sampled and evaluated for dredging and sediment disposal. Sediment samples were collected and analyses were conducted on sediment core samples. The evaluation of proposed dredged material from the channel included bulk sediment chemical analyses, chemical analyses of site water and elutriate, water column and benthic acute toxicity tests, and bioaccumulation studies. Individual sediment core samples were analyzed for grain size, moisture content, and total organic carbon. A composite sediment samples, representing the entire area proposed for dredging, was analyzed for bulk density, polynuclear aromatic hydrocarbons, and 1,4-dichlorobenzene. Site water and elutriate were analyzed for metals, pesticides, and PCBs.