Science.gov

Sample records for molecule processes semiannual

  1. Automated solar cell assembly teamed process research. Semiannual subcontract report, December 6, 1993--June 30, 1994

    SciTech Connect

    Nowlan, M.

    1995-01-01

    This is the second Semiannual Technical Progress Report for the program titled `Automated Solar Cell Assembly Teamed Process Research` funded under National Renewable Energy Laboratory (NREL) subcontract No. ZAG-3-11219-01. This report describes the work done on Phase II of the program in the period from December 6, 1993 to June 30, 1994. Spire`s objective in this program is to develop high throughput (5 MW/yr) automated processes for interconnecting thin (200 {mu}m) silicon solar cells. High yield will be achieved with these fragile cells through the development of low mechanical stress and low thermal stress processes. For example, a machine vision system is being developed for cell alignment without mechanically contacting the cell edges, while a new soldering process is being developed to solder metal interconnect ribbons simultaneously to a cells` front and back contacts, eliminating one of the two heating steps normally used for soldering each cell.

  2. Magnetospheric and auroral processes. Semiannual progress report, 1 March-31 August 1990

    SciTech Connect

    Reiff, P.H.

    1990-08-01

    Progress was made on the following two projects within the semiannual period: (1) simulations of the magnetic storm of April 1988 using the Magnetospheric Specification Model; and (2) improvement of a user-oriented electric-field model.

  3. Advanced Processing Technology semiannual report, March--December 1991. Volume 1, Number 1

    SciTech Connect

    Adamson, M.; Kline-Simon, K.

    1991-12-31

    This first issue of the APT Semiannual Report focuses on APT`s defense-related technologies. These technologies are a continuation of the research, development, and engineering work performed by LLNLs Special Isotope Separation (SIS) Program. SIS was the first large-scale DOE venture that had environmentally conscious manufacturing processes and facilities as its deliverables. The objectives were to create a facility where the only outputs were either usable products or disposable wastes, and to comply with existing and anticipated federal, state, and local regulations related to safeguards, security, health and safety. To meet these objectives, revolutionary changes were needed in plutonium processing operations, chemistry, and equipment. New processes had to be developed that enhanced worker safety, minimized operator radiation dose, minimized waste at the point of generation, and provided for built-in recycling of residues. The SIS Program developed and demonstrated the technology (both chemistry and physics) necessary to provide plutonium with individual isotopic tailoring. This process made it possible to transform fuel-grade plutonium into weapon-grade material. However, due to the changing world political climate, the country`s need for plutonium to make new weapons has decreased dramatically. As a result, the planned SIS plutonium-separation plant will not be built. After the SIS Program was canceled in 199 1, Congress directed that the plutonium processing technologies under development for the SIS Program be redirected to the weapons program. APT took over the development of the innovative SIS technologies and is applying them to the development of a new, reconfigured Nuclear Weapons Complex -- Complex 21. ``Close Out of the SIS Program`` describes the completion of the SIS research and development work, and the transfer of key technologies to support this reconfiguration effort.

  4. Annual and semi-annual variability in the lower and upper atmosphere-ionosphere coupling processes by observations from Abastumani (41.75 N, 42.82 E)

    NASA Astrophysics Data System (ADS)

    Didebulidze, G. G.; Todua, M.; Javakhishvili, G.

    2015-12-01

    The importance of annual and semi-annual variability in the long-term variations of the ionosphere F2 layer parameters (NmF2, hmF2), the hydroxyl OH bands, the oxygen green 557.7 nm and red 630.0 line intensities observed from Abastumani is noted. The amplitudes of the semi-annual variations of these upper atmosphere-ionosphere parameters with maxima at equinoctial months depend on the value of the planetary geomagnetic Ap index, also observed in the inter-annual distribution of the total ozone content (TOC) and cloud covering over this region of South Caucasus. The observed dependence of semi-annual variations of these parameters on Ap index indicated possible influence of cosmic factors on the lower and upper atmosphere-ionosphere coupling processes.

  5. COCIS: Markov processes in single molecule fluorescence

    PubMed Central

    Talaga, David S.

    2009-01-01

    This article examines the current status of Markov processes in single molecule fluorescence. For molecular dynamics to be described by a Markov process, the Markov process must include all states involved in the dynamics and the FPT distributions out of those states must be describable by a simple exponential law. The observation of non-exponential first-passage time distributions or other evidence of non-Markovian dynamics is common in single molecule studies and offers an opportunity to expand the Markov model to include new dynamics or states that improve understanding of the system. PMID:19543444

  6. Electron-atom /molecule/ collision processes

    NASA Technical Reports Server (NTRS)

    Trajmar, S.

    1980-01-01

    Electron-atom (molecule) collision processes at low and intermediate energies, from near threshold to a few hundred electron volts, are discussed. Attention is given to experimental techniques and procedures, electron impact cross sections, impact excitation and electron-atom scattering in laser fields. Specific examples are presented that illustrate various experimental techniques and interpretations of observations.

  7. PREFACE: Processes in Isotopes and Molecules

    NASA Astrophysics Data System (ADS)

    Bogdan, Diana; Tosa, Valer

    2009-07-01

    These Proceedings present some of the Invited Lectures and Contributed Papers of the International Conference 'Processes in Isotopes and Molecules' (PIM), held in Cluj-Napoca, Romania, 24-26 September 2009. The PIM conference, started in 1999 as a local event, is now an international conference organized every two years by the National Institute for R&D of Isotopic and Molecular Technologies in Cluj-Napoca, the capital city of Transylvania, Romania. The meetings are attended by researchers in the field of atomic and molecular physics as well as those developing new materials and technologies. The scientific subjects are at the cross-roads of three fundamental research areas: physics, chemistry, and biology. The papers here are grouped according to the five conference topics: T1 - Molecular and biomolecular systems T2 - Modern techniques and technologies T3 - Environmental molecular processes T4 - Hydrogen and renewable sources of energy T5 - Nanostructured materials and nanocomposites We gratefully acknowledge the contribution of our colleagues from the Scientific Committee and Program Committee who contributed their time, energy and expertise to the refereeing process. Finally, we would like to thank people from IOP Publishing for their friendly advice and prompt help during the editing process, as well as for their efforts making the Journal of Physics: Conference Series available to the scientific community. Diana Bogdan and Valer Tosa National Institute for R&D Isotopic and Molecular Technologies, Cluj-Napoca

  8. Note on the semi-annual effect in the thermosphere

    NASA Technical Reports Server (NTRS)

    Volland, H.; Mayr, H. G.

    1972-01-01

    The semi-annual variation in the thermospheric density is discussed in terms of the spatial and temporal variations in the solar heat input. Two heat sources are considered: the solar heat input associated with the semi-annual migration of the sun, and the auroral heat associated with the semi-annual component in magnetic storms. It is shown that the relatively large global component in the semi-annual effect of the total mass density can be explained by the lack of advective loss which otherwise damps the latitude dependent components in the annual and semi-annual variations, and the significant latitude dependence in the semi-annual variations of composition and temperature can be tied to the diffusion process which is induced by the thermospheric circulation.

  9. Development of an intelligent grinding wheel for in-process monitoring of ceramic grinding. Semi-annual report {number_sign}3

    SciTech Connect

    Malkin, S.; Gao, R.; Guo, C.; Varghese, B.; Pathare, S.

    1998-03-26

    This is the third semi-annual report for the project. The overall objective of this project is to develop sensor-integrated intelligent diamond wheels for grinding of ceramics. Such wheels will be smart enough to monitor and supervise both the wheel preparation and grinding processes without the need to instrument the machine tool. Intelligent wheels will utilize re-useable cores integrated with sensors: to measure the acoustic emission (AE) and grinding force. Signals from the sensors will be transmitted from a rotating wheel to a receiver by telemetry. Wheels will be trained to recognize distinct characteristics associated with truing, dressing and grinding. The technical progress is summarized in this report.

  10. Non-equilibrium processes in interstellar molecules

    NASA Technical Reports Server (NTRS)

    Strelnitskiy, V. S.

    1979-01-01

    The types of nonequilibrium emission and absorption by interstellar molecules are summarized. The observed brightness emission temperatures of compact OH and H2O sources are discussed using the concept of maser amplification. A single thermodynamic approach was used in which masers and anti-masers are considered as heat engines for the theoretical interpretation of the cosmic maser and anti-maser phenomena. The requirements for different models of pumping are formulated and a classification is suggested for the mechanisms of pumping, according to the source and discharge of energy.

  11. HTGR process heat program design and analysis. Semiannual progress report, October 1, 1979-March 28, 1980

    SciTech Connect

    Not Available

    1980-10-01

    This report summarizes the results of concept design studies implemented at General Atomic Company (GA) during the first half of FY-80. The studies relate to a plant design for an 842-MW(t) High-Temperature Gas-Cooled Reactor utilizing an intermediate helium heat transfer loop to provide high temperature thermal energy for the production of hydrogen or synthesis gas (H/sub 2/ + CO) by steam-reforming a light hydrocarbon. Basic carbon sources may be coal, residual oil, or oil shale. Work tasks conducted during this period included the 842-MW(t) plant concept design and cost estimate for an 850/sup 0/C reactor outlet temperature. An assessment of the main-loop cooling shutdown system is reported. Major component cost models were prepared and programmed into the Process Heat Reactor Evaluation and Design (PHRED) code.

  12. Research in laser processes. Semiannual report, 1 February-31 July 1979

    SciTech Connect

    Phelps, A.V.; Gallagher, A.C.

    1980-04-15

    A model has been completed of the NaXe discharges examined experimentally under this contract. This model includes the effects of electron excitation, deexcitation and ionization of excited Na atoms, as well as electron loss processes such as dissociative recombination with Na2(+). By adopting apparently reasonable rate coefficients and reaction end products we are able to satisfactorily reproduce the measured steady-state densities of excited Na atoms. However, a serious and unexplained discrepancy is found in the energy balance for these discharges. By extrapolating these results to high Na densities we find what appears to be a region of sufficient optical gain at 700 nm for laser oscillation. Such a laser would require a short excitation pulse (approx. 100 ns) and would have a low discharge impedance. A new technique has been developed for the measurement of electron excitation rate coefficients for the metastable states of the rare gases. A multipass absorption cell and a single mode dye laser allow measurement of metastable densities as low as 1,000,000 atom/cc.

  13. Materials technology for coal-conversion process. Semiannual report, October 1981-March 1982

    SciTech Connect

    Not Available

    1982-06-01

    This report describes progress in seven areas for the period from October 1, 1981 to March 31, 1982. Work on Refractories for Slagging Gasifiers has included studies of corrosion, thermal shock, and slag viscosity. The Structural Ceramics program has focused on establishing materials parameters for large-scale heat exchanger tests, selecting conditions and materials for laboratory-scale tests of structural ceramic materials to be used in heat exchangers, and developing advanced inspection techniques for ceramic heat exchanger tubes. High-Temperature Gaseous Corrosion efforts continue to examine the effects of mixed oxidants on corrosion behavior and mechanical properties. Work on Protective Coatings and Claddings has been concerned with metal and ceramic coatings, including pack aluminizing, pack chromizing, and plasma spray methods. Instrumentation Development for In-situ Erosion Monitoring has concentrated on systems to monitor erosive wear of both metal and ceramics, primarily using acoustics. Large-Scale Plant Design Reviews have focused on the Mountain Fuel Resources (MFR) and Hydrocarbon Research, Inc. process development units, with emphasis on review of the MFR plant. The work on Erosive Wear in High-Temperature Slurry Pumps has consisted of an extensive review of available operating experience.

  14. Extending Single-Molecule Microscopy Using Optical Fourier Processing

    PubMed Central

    2015-01-01

    This article surveys the recent application of optical Fourier processing to the long-established but still expanding field of single-molecule imaging and microscopy. A variety of single-molecule studies can benefit from the additional image information that can be obtained by modulating the Fourier, or pupil, plane of a widefield microscope. After briefly reviewing several current applications, we present a comprehensive and computationally efficient theoretical model for simulating single-molecule fluorescence as it propagates through an imaging system. Furthermore, we describe how phase/amplitude-modulating optics inserted in the imaging pathway may be modeled, especially at the Fourier plane. Finally, we discuss selected recent applications of Fourier processing methods to measure the orientation, depth, and rotational mobility of single fluorescent molecules. PMID:24745862

  15. Autophagy proteins in antigen processing for presentation on MHC molecules.

    PubMed

    Münz, Christian

    2016-07-01

    Autophagy describes catabolic pathways that deliver cytoplasmic constituents for lysosomal degradation. Since major histocompatibility complex (MHC) molecules sample protein degradation products and present them to T cells for adaptive immunity, it is maybe not too surprising that autophagy contributes to this protein antigen processing for MHC presentation. However, the recently recognized breath of pathways, by which autophagy contributes to MHC antigen processing, is exciting. Macroautophagy does not only seem to deliver intracellular but facilitates also extracellular antigen processing by lysosomal hydrolysis for MHC class II presentation. Moreover, even MHC class I molecules that usually display proteasomal products are regulated by macroautophagy, probably using a pool of these molecules outside the endoplasmic reticulum, where MHC class I molecules are loaded with peptide during canonical MHC class I antigen processing. This review aims to summarize these recent developments and point out gaps of knowledge, which should be filled by further investigation, in order to harness the different antigen-processing pathways via autophagy for vaccine improvement. PMID:27319339

  16. Securities and Exchange Commission Semiannual Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-26

    ... [Securities and Exchange Commission Semiannual Regulatory Agenda ] Part XXIII Securities and Exchange Commission Semiannual Regulatory Agenda ] SECURITIES AND EXCHANGE COMMISSION (SEC) SECURITIES AND EXCHANGE COMMISSION 17 CFR Ch. II Regulatory Flexibility Agenda AGENCY: Securities and Exchange Commission. ACTION: Semiannual regulatory...

  17. Proposed geomagnetic control of semiannual waves in the mesospheric zonal wind

    NASA Technical Reports Server (NTRS)

    Belmont, A. D.; Nastrom, G. D.; Mayr, H. G.

    1974-01-01

    The polar semiannual oscillation in zonal wind can explain midwinter weakening of the polar vortex and the relatively short stratospheric and mesospheric summar easterlies. The phase of the wind oscillation is equinoctial, as is the phase of the semiannual component in magnetic storm activity. For a given altitude, the contours of amplitude of the semiannual wind oscillation have less variability in geomagnetic than in geographic coordinates. It is suggested that polar wind oscillations are caused by the semiannual maxima in magnetic storm activity which lead to electron dissociation of O2 into O, in turn increasing ozone more rapidly than the dissociation of N2 destroys ozone, and thereby inducing a semiannual variation in the thermal and wind fields. This implies that geomagnetic processes may cause or affect the development of sudden warmings. As the tropical semiannual wind oscillation is symmetric about the geomagnetic equator, the same processes may also influence the location of the tropical wind wave.

  18. Proposed geomagnetic control of semiannual waves in the mesospheric zonal wind

    NASA Technical Reports Server (NTRS)

    Belmont, A. D.; Nastrom, G. D.; Mayr, H. G.

    1975-01-01

    The polar semiannual oscillation in zonal wind explains midwinter weakening of the polar vortex and the relatively short stratospheric and mesospheric summer easterlies. The phase of the wind oscillation is equinoctial, as is the phase of the semiannual component in magnetic storm activity. For a given altitude, the contours of amplitude of the semiannual wind oscillation have less variability in geomagnetic than in geographic coordinates. It is suggested that the polar wind oscillations are caused by the semiannual maxima in magnetic storm activity, which lead to electron dissociation of O2 into O, in turn increasing ozone more rapidly than the dissociation of N2 destroys ozone, and inducing a semiannual variation in the thermal and wind fields. This implies that geomagnetic processes may cause or affect the development of sudden warmings. As the tropical semiannual wind oscillation is symmetric about the geomagnetic equator, the same processes may also influence the location of the tropical wind wave.

  19. Towards Hybrid Quantum Information Processing with Polar Molecules

    NASA Astrophysics Data System (ADS)

    Rabl, Peter

    2008-05-01

    With the ongoing miniaturization of on-chip traps for atoms and ions it is timely to think about coherent interfaces between AMO and solid state systems with potential applications for new hybrid implementations for quantum computers. In this talk I will discuss a potential scenario, where ensembles of polar molecules serve as long-lived quantum memories for superconducting qubits and quantum information is transmitted via a high-Q microwave cavity. Polar molecules combine the exceptional features of a large electric dipole moment and long-lived rotational states with level splittings in the GHz regime. When trapped close to the surface of a chip this combination allows strong interactions with coherent solid state devices, e.g., superconducting microwave cavities or Josephson qubits. I will first introduce the system consisting of a single polar molecule coupled to a stripline cavity which realizes a cavity QED system in the microwave regime and discuss applications for quantum information processing, state detection and new cavity-assisted cooling schemes for polar molecules. I will then switch to molecular ensemble qubits where quantum information is encoded in collective spin or rotational excitations of an ensemble of N molecules. Ensemble qubits benefit from a collectively enhanced coupling ˜√N which allows quantum state transfer between the molecules and, e.g., a charge qubit on a timescale that is compatible with typical coherence times in a solid state environment. With the goal to protect ensemble qubits from collisions, I will finally discuss a scenario, where molecules are prepared in a crystalline phase under 1D trapping conditions and dipole moments aligned by an external field.

  20. Single Molecule Electron Transfer Process of Ruthenium Complexes.

    SciTech Connect

    Hu, Dehong; Lu, H PETER.

    2006-03-01

    Transition metal complexes such as ruthenium complexes, having metal-to-ligand charge transfer states, are extensively used in solar energy conversion and electron transfer in biological systems and at interfaces. The dynamics of metal-to-ligand charge transfer and subsequent intermolecular, intramolecular, and interfacial electron transfer processes can be highly complex and inhomogeneous, especially when molecules are involved in interactions and perturbations from heterogeneous local environments and gated by conformation fluctuations. We have employed the single-molecule spectroscopy, a powerful approach for inhomogeneous systems to study the electron transfer dynamics of ruthenium complexes. We have applied a range of statistical analysis methods to reveal nonclassical photon emission behavior of the single ruthenium complex, i.e., photon antibunching, and photophysical ground-state recovering dynamics on a microsecond time scale. The use of photon antibunching to measure phosphorescence lifetimes and single-molecule electron transfer dynamics at room temperature is demonstrated.

  1. Energy landscape exploration of the folding processes of biological molecules

    NASA Astrophysics Data System (ADS)

    Engel, Megan Clare

    For decades, scientists from every discipline have struggled to understand the mechanism of biological self-assembly, which allows proteins and nucleic acids to fold reliably into functional three-dimensional structures. Such an understanding may hold the key to eliminating diseases such as Alzheimer's and Parkinson's and to effective protein engineering. The current best framework for describing biological folding processes is that of statistical mechanical energy landscape theory, and one of the most promising experimental techniques for exploring molecular energy landscapes is single molecule force spectroscopy (SMFS), in which molecules are mechanically denatured. Theoretical advances have enabled the extraction of complete energy landscape profiles from SMFS data. Here, SMFS experiments performed using laser optical tweezers are analyzed to yield the first ever full landscape profile for an RNA pseudoknot. Further, a promising novel landscape reconstruction technique is validated for the first time using experimental data from a DNA hairpin.

  2. Elementary processes during collisions of ions with tryptophan molecules

    NASA Astrophysics Data System (ADS)

    Afrosimov, V. V.; Basalaev, A. A.; Kuz'michev, V. V.; Panov, M. N.; Smirnov, O. V.

    2016-03-01

    The relative cross sections of elementary processes occurring in single collisions of tryptophan molecules in the gaseous phase with He2+ ions with energy 4 keV/u are measured using time-of-flight mass spectrometry for studying the mechanism of radiation damage of amino acid molecules. The fragmentation channels for intermediate singly and doubly charged tryptophan molecular ions formed during one-electron capture, two-electron capture, and electron capture with ionization are investigated. Significant difference is observed in the mass spectra of fragmentation of intermediate doubly charged ions formed during the capture with ionization and double capture, which is associated with different energies of excitation of {C11H12N2O2}2+* ions.

  3. Living is information processing: from molecules to global systems.

    PubMed

    Farnsworth, Keith D; Nelson, John; Gershenson, Carlos

    2013-06-01

    We extend the concept that life is an informational phenomenon, at every level of organisation, from molecules to the global ecological system. According to this thesis: (a) living is information processing, in which memory is maintained by both molecular states and ecological states as well as the more obvious nucleic acid coding; (b) this information processing has one overall function-to perpetuate itself; and (c) the processing method is filtration (cognition) of, and synthesis of, information at lower levels to appear at higher levels in complex systems (emergence). We show how information patterns, are united by the creation of mutual context, generating persistent consequences, to result in 'functional information'. This constructive process forms arbitrarily large complexes of information, the combined effects of which include the functions of life. Molecules and simple organisms have already been measured in terms of functional information content; we show how quantification may be extended to each level of organisation up to the ecological. In terms of a computer analogy, life is both the data and the program and its biochemical structure is the way the information is embodied. This idea supports the seamless integration of life at all scales with the physical universe. The innovation reported here is essentially to integrate these ideas, basing information on the 'general definition' of information, rather than simply the statistics of information, thereby explaining how functional information operates throughout life. PMID:23456459

  4. Modelling low-energy electron-molecule capture processes.

    PubMed

    Dashevskaya, E I; Litvin, I; Nikitin, E E; Troe, J

    2008-03-01

    Cross sections and rate coefficients for capture of low-energy electrons with polar and polarizable target molecules are calculated in the framework of Fabrikant and Hotop's extended version of the Vogt-Wannier model and an extension of this approach is given in the present article. Analytical approximations are derived in order to facilitate the application to experiments. A comparison with a selection of experimental electron attachment rate coefficients provides insight into the competition between anion formation through electron capture and scattering processes which do not follow this pathway. PMID:18292861

  5. Processive cytoskeletal motors studied with single-molecule fluorescence techniques

    PubMed Central

    Belyy, Vladislav; Yildiz, Ahmet

    2014-01-01

    Processive cytoskeletal motors from the myosin, kinesin, and dynein families walk on actin filaments and microtubules to drive cellular transport and organization in eukaryotic cells. These remarkable molecular machines are able to take hundreds of successive steps at speeds of up to several microns per second, allowing them to effectively move vesicles and organelles throughout the cytoplasm. Here, we focus on single-molecule fluorescence techniques and discuss their wide-ranging applications to the field of cytoskeletal motor research. We cover both traditional fluorescence and sub-diffraction imaging of motors, providing examples of how fluorescence data can be used to measure biophysical parameters of motors such as coordination, stepping mechanism, gating, and processivity. We also outline some remaining challenges in the field and suggest future directions. PMID:24882363

  6. Collective relaxation processes in atoms, molecules and clusters

    NASA Astrophysics Data System (ADS)

    Kolorenč, Přemysl; Averbukh, Vitali; Feifel, Raimund; Eland, John

    2016-04-01

    Electron correlation is an essential driver of a variety of relaxation processes in excited atomic and molecular systems. These are phenomena which often lead to autoionization typically involving two-electron transitions, such as the well-known Auger effect. However, electron correlation can give rise also to higher-order processes characterized by multi-electron transitions. Basic examples include simultaneous two-electron emission upon recombination of an inner-shell vacancy (double Auger decay) or collective decay of two holes with emission of a single electron. First reports of this class of processes date back to the 1960s, but their investigation intensified only recently with the advent of free-electron lasers. High fluxes of high-energy photons induce multiple excitation or ionization of a system on the femtosecond timescale and under such conditions the importance of multi-electron processes increases significantly. We present an overview of experimental and theoretical works on selected multi-electron relaxation phenomena in systems of different complexity, going from double Auger decay in atoms and small molecules to collective interatomic autoionization processes in nanoscale samples.

  7. Single molecule study of a processivity clamp sliding on DNA

    SciTech Connect

    Laurence, T A; Kwon, Y; Johnson, A; Hollars, C; O?Donnell, M; Camarero, J A; Barsky, D

    2007-07-05

    Using solution based single molecule spectroscopy, we study the motion of the polIII {beta}-subunit DNA sliding clamp ('{beta}-clamp') on DNA. Present in all cellular (and some viral) forms of life, DNA sliding clamps attach to polymerases and allow rapid, processive replication of DNA. In the absence of other proteins, the DNA sliding clamps are thought to 'freely slide' along the DNA; however, the abundance of positively charged residues along the inner surface may create favorable electrostatic contact with the highly negatively charged DNA. We have performed single-molecule measurements on a fluorescently labeled {beta}-clamp loaded onto freely diffusing plasmids annealed with fluorescently labeled primers of up to 90 bases. We find that the diffusion constant for 1D diffusion of the {beta}-clamp on DNA satisfies D {le} 10{sup -14} cm{sup 2}/s, much slower than the frictionless limit of D = 10{sup -10} cm{sup 2}/s. We find that the {beta} clamp remains at the 3-foot end in the presence of E. coli single-stranded binding protein (SSB), which would allow for a sliding clamp to wait for binding of the DNA polymerase. Replacement of SSB with Human RP-A eliminates this interaction; free movement of sliding clamp and poor binding of clamp loader to the junction allows sliding clamp to accumulate on DNA. This result implies that the clamp not only acts as a tether, but also a placeholder.

  8. High performance photovoltaic applications using solution-processed small molecules.

    PubMed

    Chen, Yongsheng; Wan, Xiangjian; Long, Guankui

    2013-11-19

    Energy remains a critical issue for the survival and prosperity of humancivilization. Many experts believe that the eventual solution for sustainable energy is the use of direct solar energy as the main energy source. Among the options for renewable energy, photovoltaic technologies that harness solar energy offer a way to harness an unlimited resource and minimum environment impact in contrast with other alternatives such as water, nuclear, and wind energy. Currently, almost all commercial photovoltaic technologies use Si-based technology, which has a number of disadvantages including high cost, lack of flexibility, and the serious environmental impact of the Si industry. Other technologies, such as organic photovoltaic (OPV) cells, can overcome some of these issues. Today, polymer-based OPV (P-OPV) devices have achieved power conversion efficiencies (PCEs) that exceed 9%. Compared with P-OPV, small molecules based OPV (SM-OPV) offers further advantages, including a defined structure for more reproducible performance, higher mobility and open circuit voltage, and easier synthetic control that leads to more diversified structures. Therefore, while largely undeveloped, SM-OPV is an important emerging technology with performance comparable to P-OPV. In this Account, we summarize our recent results on solution-processed SM-OPV. We believe that solution processing is essential for taking full advantage of OPV technologies. Our work started with the synthesis of oligothiophene derivatives with an acceptor-donor-acceptor (A-D-A) structure. Both the backbone conjugation length and electron withdrawing terminal groups play an important role in the light absorption, energy levels and performance of the devices. Among those molecules, devices using a 7-thiophene-unit backbone and a 3-ethylrhodanine (RD) terminal unit produced a 6.1% PCE. With the optimized conjugation length and terminal unit, we borrowed from the results with P-OPV devices to optimize the backbone. Thus we

  9. Automated solar cell assembly teamed process research. Semiannual subcontract report, 7 January 1993--30 June 1993

    SciTech Connect

    Nowlan, M.J.; Hogan, S.J.; Darkazalli, G.; Breen, W.F.; Murach, J.M.; Sutherland, S.F.

    1994-02-01

    This report describes work done under Phase 3A of the PVMaT project to address problems that are generic to the photovoltaics (PV) industry. Crystalline silicon solar cells were used in the majority of all terrestrial power modules shipped in 1992. Spire`s analysis in Phase 1 of the PVMaT project indicated that the use of thin ({le}200-{mu}m) silicon cells can substantially reduce module manufacturing costs, provided that processing yields remain as high as they are now for processing standard thickness cells. Because present solar cell tabbing and interconnecting processes have unacceptably high yield losses with such thin cells, the objective of this Phase 3A subcontract is to use Spire`s light soldering technology and experience in designing and fabricating solar cell tabbing and interconnecting equipment to develop high yield throughput, fully automated processes for tabbing and interconnecting thin cells.

  10. Single molecule image formation, reconstruction and processing: introduction.

    PubMed

    Ashok, Amit; Piestun, Rafael; Stallinga, Sjoerd

    2016-07-01

    The ability to image at the single molecule scale has revolutionized research in molecular biology. This feature issue presents a collection of articles that provides new insights into the fundamental limits of single molecule imaging and reports novel techniques for image formation and analysis. PMID:27409708

  11. HTGR-process steam/cogeneration and HTGR-steam cycle program. Semiannual report, October 1, 1979-March 31, 1980

    SciTech Connect

    Not Available

    1980-09-01

    Progress in the design of an 1170-MW(t) High-Temperature Gas-Cooled Reactor (HTGR) Nuclear Steam Supply (NSS) is described. This NSS can integrate favorably into present petrochemical and primary metal process industries, heavy oil recovery operations, and future shale oil recovery and synfuel processes. The economics appear especially attractive in comparison with alternative coal-fired steam generation. Cost estimates for central station power-generating 2240- and 3360-MW(t) HTGR-Steam Cycle (HTGR-SC) plants are updated. The 2240-MW(t) HTGR-SC is treated to a probabilistic risk evaluation. Compared with the earlier 3000-MW(t) design, the results predict a slightly increased risk of core heatup, owing to the result of eliminating the capability of the boiler feed pump to operate at atmospheric backpressure. The differences in risk, however, are within the calculational uncertainties. Preliminary results of the ranking of safety enhancement features for the 1170-MW(t) HTGR indicate that the following modifications offer the most promise: (1) capability for main loop rundown, (2) natural circulation core auxiliary cooling, and (3) PCRV blowdown capability through the helium purification system to minimize activity release during some core heatups.

  12. Flexible single molecule simulation of reaction-diffusion processes

    SciTech Connect

    Hellander, Stefan; Loetstedt, Per

    2011-05-10

    An algorithm is developed for simulation of the motion and reactions of single molecules at a microscopic level. The molecules diffuse in a solvent and react with each other or a polymer and molecules can dissociate. Such simulations are of interest e.g. in molecular biology. The algorithm is similar to the Green's function reaction dynamics (GFRD) algorithm by van Zon and ten Wolde where longer time steps can be taken by computing the probability density functions (PDFs) and then sample from the distribution functions. Our computation of the PDFs is much less complicated than GFRD and more flexible. The solution of the partial differential equation for the PDF is split into two steps to simplify the calculations. The sampling is without splitting error in two of the coordinate directions for a pair of molecules and a molecule-polymer interaction and is approximate in the third direction. The PDF is obtained either from an analytical solution or a numerical discretization. The errors due to the operator splitting, the partitioning of the system, and the numerical approximations are analyzed. The method is applied to three different systems involving up to four reactions. Comparisons with other mesoscopic and macroscopic models show excellent agreement.

  13. A comprehensive glossary of autophagy-related molecules and processes

    PubMed Central

    Klionsky, Daniel J.; Codogno, Patrice; Cuervo, Ana Maria; Deretic, Vojo; Elazar, Zvulun; Fueyo-Margareto, Juan; Gewirtz, David A.; Kroemer, Guido; Levine, Beth; Mizushima, Noboru; Rubinsztein, David C.; Thumm, Michael; Tooze, Sharon A.

    2013-01-01

    Autophagy is a rapidly expanding field in the sense that our knowledge about the molecular mechanism and its connections to a wide range of physiological processes has increased substantially in the past decade. Similarly, the vocabulary associated with autophagy has grown concomitantly. This fact makes it difficult for readers, even those who work in the field, to keep up with the ever-expanding terminology associated with the various autophagy-related processes. Accordingly, we have developed a comprehensive glossary of autophagy-related terms that is meant to provide a quick reference for researchers who need a brief reminder of the regulatory effects of transcription factors or chemical agents that induce or inhibit autophagy, the function of the autophagy-related proteins, or the role of accessory machinery or structures that are associated with autophagy. PMID:20484971

  14. Department of Labor Semiannual Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-26

    ... Part XI Department of Labor Semiannual Regulatory Agenda ] DEPARTMENT OF LABOR (DOL) DEPARTMENT OF LABOR Office of the Secretary 20 CFR Chs. I, IV, V, VI, VII, and IX 29 CFR Subtitle A and Chs. II, IV, V, XVII, and XXV 30 CFR Ch. I 41 CFR Ch. 60 48 CFR Ch. 29 Semiannual Agenda of Regulations AGENCY: Office of the Secretary, Labor....

  15. Department of Justice Semiannual Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-20

    ... [The Regulatory Plan and Unified Agenda of Federal Regulatory and Deregulatory Actions] Part XI Department of Justice Semiannual Regulatory Agenda ] DEPARTMENT OF JUSTICE (DOJ) DEPARTMENT OF JUSTICE 8 CFR Ch. V 21 CFR Ch. I 27 CFR Ch. II 28 CFR Ch. I, V Regulatory Agenda AGENCY: Department of Justice. ACTION: Semiannual regulatory agenda....

  16. 78 FR 1570 - Semiannual Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-08

    ... January 8, 2013 Part VII Department of Energy Semiannual Regulatory Agenda #0;#0;Federal Register / Vol. 78 , No. 5 / Tuesday, January 8, 2013 / Unified Agenda#0;#0; ] DEPARTMENT OF ENERGY 10 CFR Chs. II, III, and X 48 CFR Ch. 9 Semiannual Regulatory Agenda AGENCY: Department of Energy. ACTION: Notice...

  17. The artificial control of enhanced optical processes in fluorescent molecules on high-emittance metasurfaces

    NASA Astrophysics Data System (ADS)

    Iwanaga, Masanobu; Choi, Bongseok; Miyazaki, Hideki T.; Sugimoto, Yoshimasa

    2016-05-01

    Plasmon-enhanced optical processes in molecules have been extensively but individually explored for Raman scattering, fluorescence, and infrared light absorption. In contrast to recent progress in the interfacial control of hot electrons in plasmon-semiconductor hybrid systems, plasmon-molecule hybrid systems have remained to be a conventional scheme, mainly assuming electric-field enhancement. This was because it was difficult to control the plasmon-molecule interface in a well-controlled manner. We here experimentally substantiate an obvious change in artificially enhanced optical processes of fluorescence/Raman scattering in fluorescent molecules on high-emittance plasmo-photonic metasurfaces with/without a self-assembled monolayer of sub-nm thickness. These results indicate that the enhanced optical processes were successfully selected under artificial configurations without any additional chemical treatment that modifies the molecules themselves. Although Raman-scattering efficiency is generally weak in high-fluorescence-yield molecules, it was found that Raman scattering becomes prominent around the molecular fingerprint range on the metasurfaces, being enhanced by more than 2000 fold at the maximum for reference signals. In addition, the highly and uniformly enhancing metasurfaces are able to serve as two-way functional, reproducible, and wavelength-tunable platforms to detect molecules at very low densities, being distinct from other platforms reported so far. The change in the enhanced signals suggests that energy diagrams in fluorescent molecules are changed in the configuration that includes the metal-molecule interface, meaning that plasmon-molecule hybrid systems are rich in the phenomena beyond the conventional scheme.Plasmon-enhanced optical processes in molecules have been extensively but individually explored for Raman scattering, fluorescence, and infrared light absorption. In contrast to recent progress in the interfacial control of hot electrons

  18. The artificial control of enhanced optical processes in fluorescent molecules on high-emittance metasurfaces.

    PubMed

    Iwanaga, Masanobu; Choi, Bongseok; Miyazaki, Hideki T; Sugimoto, Yoshimasa

    2016-06-01

    Plasmon-enhanced optical processes in molecules have been extensively but individually explored for Raman scattering, fluorescence, and infrared light absorption. In contrast to recent progress in the interfacial control of hot electrons in plasmon-semiconductor hybrid systems, plasmon-molecule hybrid systems have remained to be a conventional scheme, mainly assuming electric-field enhancement. This was because it was difficult to control the plasmon-molecule interface in a well-controlled manner. We here experimentally substantiate an obvious change in artificially enhanced optical processes of fluorescence/Raman scattering in fluorescent molecules on high-emittance plasmo-photonic metasurfaces with/without a self-assembled monolayer of sub-nm thickness. These results indicate that the enhanced optical processes were successfully selected under artificial configurations without any additional chemical treatment that modifies the molecules themselves. Although Raman-scattering efficiency is generally weak in high-fluorescence-yield molecules, it was found that Raman scattering becomes prominent around the molecular fingerprint range on the metasurfaces, being enhanced by more than 2000 fold at the maximum for reference signals. In addition, the highly and uniformly enhancing metasurfaces are able to serve as two-way functional, reproducible, and wavelength-tunable platforms to detect molecules at very low densities, being distinct from other platforms reported so far. The change in the enhanced signals suggests that energy diagrams in fluorescent molecules are changed in the configuration that includes the metal-molecule interface, meaning that plasmon-molecule hybrid systems are rich in the phenomena beyond the conventional scheme. PMID:27227964

  19. Gaussian Process Model for Collision Dynamics of Complex Molecules

    NASA Astrophysics Data System (ADS)

    Cui, Jie; Krems, Roman V.

    2015-08-01

    We show that a Gaussian process model can be combined with a small number (of order 100) of scattering calculations to provide a multidimensional dependence of scattering observables on the experimentally controllable parameters (such as the collision energy or temperature) as well as the potential energy surface (PES) parameters. For the case of Ar -C6H6 collisions, we show that 200 classical trajectory calculations are sufficient to provide a ten-dimensional hypersurface, giving the dependence of the collision lifetimes on the collision energy, internal temperature, and eight PES parameters. This can be used for solving the inverse scattering problem, for the efficient calculation of thermally averaged observables, for reducing the error of the molecular dynamics calculations by averaging over the PES variations, and for the analysis of the sensitivity of the observables to individual parameters determining the PES. Trained by a combination of classical and quantum calculations, the model provides an accurate description of the quantum scattering cross sections, even near scattering resonances.

  20. Current and potential uses of bioactive molecules from marine processing waste.

    PubMed

    Suleria, Hafiz Ansar Rasul; Masci, Paul; Gobe, Glenda; Osborne, Simone

    2016-03-15

    Food industries produce huge amounts of processing waste that are often disposed of incurring expenses and impacting upon the environment. For these and other reasons, food processing waste streams, in particular marine processing waste streams, are gaining popularity amongst pharmaceutical, cosmetic and nutraceutical industries as sources of bioactive molecules. In the last 30 years, there has been a gradual increase in processed marine products with a concomitant increase in waste streams that include viscera, heads, skins, fins, bones, trimmings and shellfish waste. In 2010, these waste streams equated to approximately 24 million tonnes of mostly unused resources. Marine processing waste streams not only represent an abundant resource, they are also enriched with structurally diverse molecules that possess a broad panel of bioactivities including anti-oxidant, anti-coagulant, anti-thrombotic, anti-cancer and immune-stimulatory activities. Retrieval and characterisation of bioactive molecules from marine processing waste also contributes valuable information to the vast field of marine natural product discovery. This review summarises the current use of bioactive molecules from marine processing waste in different products and industries. Moreover, this review summarises new research into processing waste streams and the potential for adoption by industries in the creation of new products containing marine processing waste bioactives. PMID:26332893

  1. Solution processable organic polymers and small molecules for bulk-heterojunction solar cells: A review

    SciTech Connect

    Sharma, G. D.

    2011-10-20

    Solution processed bulk heterojunction (BHJ) organic solar cells (OSCs) have gained wide interest in past few years and are established as one of the leading next generation photovoltaic technologies for low cost power production. Power conversion efficiencies up to 6% and 6.5% have been reported in the literature for single layer and tandem solar cells, respectively using conjugated polymers. A recent record efficiency about 8.13% with active area of 1.13 cm{sup 2} has been reported. However Solution processable small molecules have been widely applied for photovoltaic (PV) devices in recent years because they show strong absorption properties, and they can be easily purified and deposited onto flexible substrates at low cost. Introducing different donor and acceptor groups to construct donor--acceptor (D--A) structure small molecules has proved to be an efficient way to improve the properties of organic solar cells (OSCs). The power conversion efficiency about 4.4 % has been reported for OSCs based on the small molecules. This review deals with the recent progress of solution processable D--A structure small molecules and discusses the key factors affecting the properties of OSCs based on D--A structure small molecules: sunlight absorption, charge transport and the energy level of the molecules.

  2. Prospects for the formation of ultracold polar ground state KCs molecules via an optical process

    NASA Astrophysics Data System (ADS)

    Borsalino, D.; Vexiau, R.; Aymar, M.; Luc-Koenig, E.; Dulieu, O.; Bouloufa-Maafa, N.

    2016-03-01

    Heteronuclear alkali-metal dimers represent the class of molecules of choice for creating samples of ultracold molecules exhibiting an intrinsic large permanent electric dipole moment. Among them, the KCs molecule, with a permanent dipole moment of 1.92 Debye still remains to be observed in ultracold conditions. Based on spectroscopic studies available in the literature completed by accurate quantum chemistry calculations, we propose several optical coherent schemes to create ultracold bosonic and fermionic KCs molecules in their absolute rovibrational ground level, starting from a weakly bound level of their electronic ground state manifold. The processes rely on the existence of convenient electronically excited states allowing an efficient stimulated Raman adiabatic transfer of the level population.

  3. Positron-Electron Annihilation Process in (2,2)-Difluoropropane Molecule

    NASA Astrophysics Data System (ADS)

    Yang, Liu; Xiao-Guang, Ma; Ying-Hao, Zhu

    2016-04-01

    The positron-electron annihilation process in (2,2)-difluoropropane molecule and the corresponding gamma-ray spectra are studied by quantum chemistry method. The positrophilic electrons in (2,2)-difluoropropane molecule are found for the first time. The theoretical predictions show that the outermost 2s electrons of fluoride atoms play an important role in positron-electron annihilation process of (2,2)-difiuoropropane. In the present scheme, the correlation coefficient between the theoretical gamma-ray spectra and the experiments can be 99%. The present study gives an alternative annihilation model for positron-electron pair in larger molecules. Supported by the National Natural Science Foundation of China under Grant No. 11347011 and the Natural Science Foundation Project of Shandong Province under Grant No. ZR2011AM010 and 2014 Technology Innovation Fund of Ludong University under Grant Nos. 1d151007 and ld15l016

  4. Ionization Properties of Molecules Commonly Used for Plasma Processing of Semi-Conductors

    NASA Technical Reports Server (NTRS)

    Srivastava, S. K.

    2000-01-01

    Two types of processes are involved in plasma processing of semi-conductors. They are: plasma etching or cleaning and plasma deposition of the semi-conducting materials. For plasma etching of semi-conductors mostly halogen containing gases are used as additives to gases such as O2 and N2. For plasma deposition gases such as C2H2, SiH4, Si2H6 have been tested in the past. For an optimal performance of a reactor it is important to model the plasma. In this modeling effort electron impact excitation and ionization cross sections play a central role. For ionization balance calculations values of ionization cross sections are needed. Ion molecule reactions determine the ultimate composition of the plasma. Recently it has been discovered that the by products of many of these plasmas are per fluro hydrocarbons (PFCs) which are highly infrared absorbing species and have long life times in the atmosphere. They cause global warming. A lot of research is being pursued at the present time to find alternative molecules which do not produce global warming gases as the and product of the plasma processing reactor. There is also interest in the ionization and dissociative ionization properties of these molecules from the point view of the plasma abatement of the pollutant gases at the exhaust of the semi-conductor processing reactors. At the conference ionization and dissociative ionization properties of some of these molecules will be presented.

  5. Preface: Photon and fast Ion induced Processes in Atoms, MOlecules and Nanostructures (PIPAMON)

    NASA Astrophysics Data System (ADS)

    Kövér, László

    2016-02-01

    This Special Issue contains selected papers of contributions presented in the International Workshop on Photon and fast Ion induced Processes in Atoms, MOlecules and Nanostructures (PIPAMON), held between March 24 and 26, 2015 in Debrecen, Hungary. The venue, the Aquaticum Thermal and Wellness Hotel provided a pleasant "all-under-one-roof" environment for the event.

  6. A Simple Reduction Process for the Normal Vibrational Modes Occurring in Linear Molecules

    ERIC Educational Resources Information Center

    McInerny, William

    2005-01-01

    The students in molecular spectroscopy courses are often required to determine the permitted normal vibrations for linear molecules that belong to particular groups. The reducible group representations generated by the use of Cartesian coordinates can be reduced by the use of a simple algebraic process applied to the group representations. The…

  7. 32 CFR 70.11 - DoD semiannual report.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... DISCHARGE REVIEW BOARD (DRB) PROCEDURES AND STANDARDS § 70.11 DoD semiannual report. (a) Semiannual reports..., 1977, and Special Discharge Review Program Cases. (3) Part 3. Cases Heard under Pub. L. 95-126 by.... Semiannual DRB Report—RCS DD-M(SA) 1489; Summary of Statistics for Discharge Review Board (FY) Name of...

  8. 32 CFR 70.11 - DoD semiannual report.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 1 2014-07-01 2014-07-01 false DoD semiannual report. 70.11 Section 70.11 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE PERSONNEL, MILITARY AND CIVILIAN DISCHARGE REVIEW BOARD (DRB) PROCEDURES AND STANDARDS § 70.11 DoD semiannual report. (a) Semiannual...

  9. 18 CFR 1315.600 - Semi-annual compilation.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 2 2011-04-01 2011-04-01 false Semi-annual compilation... RESTRICTIONS ON LOBBYING Agency Reports § 1315.600 Semi-annual compilation. (a) The head of each agency shall... first semi-annual compilation shall be submitted on May 31, 1990, and shall contain a compilation of...

  10. 20 CFR 438.600 - Semi-annual compilation.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Semi-annual compilation. 438.600 Section 438....600 Semi-annual compilation. (a) The Commissioner of Social Security will collect and compile the... semi-annual compilation was submitted on May 31, 1990, and contains a compilation of the...

  11. 49 CFR 20.600 - Semi-annual compilation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 1 2011-10-01 2011-10-01 false Semi-annual compilation. 20.600 Section 20.600... Semi-annual compilation. (a) The head of each agency shall collect and compile the disclosure reports... information shall not be available for public inspection. (e) The first semi-annual compilation shall...

  12. 34 CFR 82.600 - Semi-annual compilation.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 1 2013-07-01 2013-07-01 false Semi-annual compilation. 82.600 Section 82.600....600 Semi-annual compilation. (a) The head of each agency shall collect and compile the disclosure... information shall not be available for public inspection. (e) The first semi-annual compilation shall...

  13. 20 CFR 438.600 - Semi-annual compilation.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false Semi-annual compilation. 438.600 Section 438....600 Semi-annual compilation. (a) The Commissioner of Social Security will collect and compile the... semi-annual compilation was submitted on May 31, 1990, and contains a compilation of the...

  14. 7 CFR 3018.600 - Semi-annual compilation.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 15 2012-01-01 2012-01-01 false Semi-annual compilation. 3018.600 Section 3018.600..., DEPARTMENT OF AGRICULTURE NEW RESTRICTIONS ON LOBBYING Agency Reports § 3018.600 Semi-annual compilation. (a... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  15. 44 CFR 18.600 - Semi-annual compilation.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 44 Emergency Management and Assistance 1 2013-10-01 2013-10-01 false Semi-annual compilation. 18... OF HOMELAND SECURITY GENERAL NEW RESTRICTIONS ON LOBBYING Agency Reports § 18.600 Semi-annual... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  16. 22 CFR 311.600 - Semi-annual compilation.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Semi-annual compilation. 311.600 Section 311.600 Foreign Relations PEACE CORPS NEW RESTRICTIONS ON LOBBYING Agency Reports § 311.600 Semi-annual... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  17. 7 CFR 3018.600 - Semi-annual compilation.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 15 2013-01-01 2013-01-01 false Semi-annual compilation. 3018.600 Section 3018.600..., DEPARTMENT OF AGRICULTURE NEW RESTRICTIONS ON LOBBYING Agency Reports § 3018.600 Semi-annual compilation. (a... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  18. 41 CFR 105-69.600 - Semi-annual compilation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Semi-annual compilation... Administration 69-NEW RESTRICTIONS ON LOBBYING Agency Reports § 105-69.600 Semi-annual compilation. (a) The head... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  19. 45 CFR 93.600 - Semi-annual compilation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 1 2011-10-01 2011-10-01 false Semi-annual compilation. 93.600 Section 93.600... LOBBYING Agency Reports § 93.600 Semi-annual compilation. (a) The head of each agency shall collect and... first semi-annual compilation shall be submitted on May 31, 1990, and shall contain a compilation of...

  20. 44 CFR 18.600 - Semi-annual compilation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false Semi-annual compilation. 18... OF HOMELAND SECURITY GENERAL NEW RESTRICTIONS ON LOBBYING Agency Reports § 18.600 Semi-annual... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  1. 45 CFR 1230.600 - Semi-annual compilation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 4 2012-10-01 2012-10-01 false Semi-annual compilation. 1230.600 Section 1230.600... SERVICE NEW RESTRICTIONS ON LOBBYING Agency Reports § 1230.600 Semi-annual compilation. (a) The head of... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  2. 10 CFR 601.600 - Semi-annual compilation.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Semi-annual compilation. 601.600 Section 601.600 Energy... Semi-annual compilation. (a) The head of each agency shall collect and compile the disclosure reports... information shall not be available for public inspection. (e) The first semi-annual compilation shall...

  3. 32 CFR 28.600 - Semi-annual compilation.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 1 2013-07-01 2013-07-01 false Semi-annual compilation. 28.600 Section 28.600... REGULATIONS NEW RESTRICTIONS ON LOBBYING Agency Reports § 28.600 Semi-annual compilation. (a) The head of each... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  4. 49 CFR 20.600 - Semi-annual compilation.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 1 2013-10-01 2013-10-01 false Semi-annual compilation. 20.600 Section 20.600... Semi-annual compilation. (a) The head of each agency shall collect and compile the disclosure reports... information shall not be available for public inspection. (e) The first semi-annual compilation shall...

  5. 45 CFR 1230.600 - Semi-annual compilation.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 4 2013-10-01 2013-10-01 false Semi-annual compilation. 1230.600 Section 1230.600... SERVICE NEW RESTRICTIONS ON LOBBYING Agency Reports § 1230.600 Semi-annual compilation. (a) The head of... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  6. 32 CFR 28.600 - Semi-annual compilation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Semi-annual compilation. 28.600 Section 28.600... REGULATIONS NEW RESTRICTIONS ON LOBBYING Agency Reports § 28.600 Semi-annual compilation. (a) The head of each... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  7. 45 CFR 604.600 - Semi-annual compilation.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 3 2013-10-01 2013-10-01 false Semi-annual compilation. 604.600 Section 604.600... RESTRICTIONS ON LOBBYING Agency Reports § 604.600 Semi-annual compilation. (a) The head of each agency shall... first semi-annual compilation shall be submitted on May 31, 1990, and shall contain a compilation of...

  8. 49 CFR 20.600 - Semi-annual compilation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 1 2012-10-01 2012-10-01 false Semi-annual compilation. 20.600 Section 20.600... Semi-annual compilation. (a) The head of each agency shall collect and compile the disclosure reports... information shall not be available for public inspection. (e) The first semi-annual compilation shall...

  9. 22 CFR 519.600 - Semi-annual compilation.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 2 2012-04-01 2009-04-01 true Semi-annual compilation. 519.600 Section 519.600... Semi-annual compilation. (a) The head of each agency shall collect and compile the disclosure reports... information shall not be available for public inspection. (e) The first semi-annual compilation shall...

  10. 38 CFR 45.600 - Semi-annual compilation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Semi-annual compilation... (CONTINUED) NEW RESTRICTIONS ON LOBBYING Agency Reports § 45.600 Semi-annual compilation. (a) The head of... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  11. 29 CFR 93.600 - Semi-annual compilation.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 1 2013-07-01 2013-07-01 false Semi-annual compilation. 93.600 Section 93.600 Labor Office of the Secretary of Labor NEW RESTRICTIONS ON LOBBYING Agency Reports § 93.600 Semi-annual... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  12. 24 CFR 87.600 - Semi-annual compilation.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 1 2012-04-01 2012-04-01 false Semi-annual compilation. 87.600... Development NEW RESTRICTIONS ON LOBBYING Agency Reports § 87.600 Semi-annual compilation. (a) The head of each... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  13. 22 CFR 311.600 - Semi-annual compilation.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 2 2013-04-01 2009-04-01 true Semi-annual compilation. 311.600 Section 311.600 Foreign Relations PEACE CORPS NEW RESTRICTIONS ON LOBBYING Agency Reports § 311.600 Semi-annual... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  14. 45 CFR 1158.600 - Semi-annual compilation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 3 2011-10-01 2011-10-01 false Semi-annual compilation. 1158.600 Section 1158.600... HUMANITIES NATIONAL ENDOWMENT FOR THE ARTS NEW RESTRICTIONS ON LOBBYING Agency Reports § 1158.600 Semi-annual... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  15. 45 CFR 93.600 - Semi-annual compilation.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 1 2013-10-01 2013-10-01 false Semi-annual compilation. 93.600 Section 93.600... LOBBYING Agency Reports § 93.600 Semi-annual compilation. (a) The head of each agency shall collect and... first semi-annual compilation shall be submitted on May 31, 1990, and shall contain a compilation of...

  16. 22 CFR 227.600 - Semi-annual compilation.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Semi-annual compilation. 227.600 Section 227... § 227.600 Semi-annual compilation. (a) The head of each agency shall collect and compile the disclosure... information shall not be available for public inspection. (e) The first semi-annual compilation shall...

  17. 24 CFR 87.600 - Semi-annual compilation.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Semi-annual compilation. 87.600... Development NEW RESTRICTIONS ON LOBBYING Agency Reports § 87.600 Semi-annual compilation. (a) The head of each... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  18. 45 CFR 1230.600 - Semi-annual compilation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Semi-annual compilation. 1230.600 Section 1230.600... SERVICE NEW RESTRICTIONS ON LOBBYING Agency Reports § 1230.600 Semi-annual compilation. (a) The head of... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  19. 45 CFR 1158.600 - Semi-annual compilation.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 3 2013-10-01 2013-10-01 false Semi-annual compilation. 1158.600 Section 1158.600... HUMANITIES NATIONAL ENDOWMENT FOR THE ARTS NEW RESTRICTIONS ON LOBBYING Agency Reports § 1158.600 Semi-annual... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  20. 34 CFR 82.600 - Semi-annual compilation.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 1 2011-07-01 2011-07-01 false Semi-annual compilation. 82.600 Section 82.600....600 Semi-annual compilation. (a) The head of each agency shall collect and compile the disclosure... information shall not be available for public inspection. (e) The first semi-annual compilation shall...

  1. 40 CFR 34.600 - Semi-annual compilation.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Semi-annual compilation. 34.600 Section... NEW RESTRICTIONS ON LOBBYING Agency Reports § 34.600 Semi-annual compilation. (a) The head of each... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  2. 44 CFR 18.600 - Semi-annual compilation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Semi-annual compilation. 18... OF HOMELAND SECURITY GENERAL NEW RESTRICTIONS ON LOBBYING Agency Reports § 18.600 Semi-annual... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  3. 22 CFR 311.600 - Semi-annual compilation.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Semi-annual compilation. 311.600 Section 311.600 Foreign Relations PEACE CORPS NEW RESTRICTIONS ON LOBBYING Agency Reports § 311.600 Semi-annual... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  4. 22 CFR 138.600 - Semi-annual compilation.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Semi-annual compilation. 138.600 Section 138... § 138.600 Semi-annual compilation. (a) The head of each agency shall collect and compile the disclosure... information shall not be available for public inspection. (e) The first semi-annual compilation shall...

  5. 49 CFR 20.600 - Semi-annual compilation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Semi-annual compilation. 20.600 Section 20.600... Semi-annual compilation. (a) The head of each agency shall collect and compile the disclosure reports... information shall not be available for public inspection. (e) The first semi-annual compilation shall...

  6. 38 CFR 45.600 - Semi-annual compilation.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2012-07-01 2012-07-01 false Semi-annual compilation... (CONTINUED) NEW RESTRICTIONS ON LOBBYING Agency Reports § 45.600 Semi-annual compilation. (a) The head of... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  7. 22 CFR 519.600 - Semi-annual compilation.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Semi-annual compilation. 519.600 Section 519.600... Semi-annual compilation. (a) The head of each agency shall collect and compile the disclosure reports... information shall not be available for public inspection. (e) The first semi-annual compilation shall...

  8. 38 CFR 45.600 - Semi-annual compilation.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2011-07-01 2011-07-01 false Semi-annual compilation... (CONTINUED) NEW RESTRICTIONS ON LOBBYING Agency Reports § 45.600 Semi-annual compilation. (a) The head of... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  9. 24 CFR 87.600 - Semi-annual compilation.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 1 2011-04-01 2011-04-01 false Semi-annual compilation. 87.600... Development NEW RESTRICTIONS ON LOBBYING Agency Reports § 87.600 Semi-annual compilation. (a) The head of each... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  10. 7 CFR 3018.600 - Semi-annual compilation.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Semi-annual compilation. 3018.600 Section 3018.600..., DEPARTMENT OF AGRICULTURE NEW RESTRICTIONS ON LOBBYING Agency Reports § 3018.600 Semi-annual compilation. (a... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  11. 45 CFR 604.600 - Semi-annual compilation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 3 2011-10-01 2011-10-01 false Semi-annual compilation. 604.600 Section 604.600... RESTRICTIONS ON LOBBYING Agency Reports § 604.600 Semi-annual compilation. (a) The head of each agency shall... first semi-annual compilation shall be submitted on May 31, 1990, and shall contain a compilation of...

  12. 32 CFR 28.600 - Semi-annual compilation.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 1 2012-07-01 2012-07-01 false Semi-annual compilation. 28.600 Section 28.600... REGULATIONS NEW RESTRICTIONS ON LOBBYING Agency Reports § 28.600 Semi-annual compilation. (a) The head of each... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  13. 45 CFR 1158.600 - Semi-annual compilation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 3 2012-10-01 2012-10-01 false Semi-annual compilation. 1158.600 Section 1158.600... HUMANITIES NATIONAL ENDOWMENT FOR THE ARTS NEW RESTRICTIONS ON LOBBYING Agency Reports § 1158.600 Semi-annual... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  14. 45 CFR 604.600 - Semi-annual compilation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 3 2012-10-01 2012-10-01 false Semi-annual compilation. 604.600 Section 604.600... RESTRICTIONS ON LOBBYING Agency Reports § 604.600 Semi-annual compilation. (a) The head of each agency shall... first semi-annual compilation shall be submitted on May 31, 1990, and shall contain a compilation of...

  15. 22 CFR 519.600 - Semi-annual compilation.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Semi-annual compilation. 519.600 Section 519.600... Semi-annual compilation. (a) The head of each agency shall collect and compile the disclosure reports... information shall not be available for public inspection. (e) The first semi-annual compilation shall...

  16. 22 CFR 227.600 - Semi-annual compilation.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Semi-annual compilation. 227.600 Section 227... § 227.600 Semi-annual compilation. (a) The head of each agency shall collect and compile the disclosure... information shall not be available for public inspection. (e) The first semi-annual compilation shall...

  17. 40 CFR 34.600 - Semi-annual compilation.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Semi-annual compilation. 34.600 Section... NEW RESTRICTIONS ON LOBBYING Agency Reports § 34.600 Semi-annual compilation. (a) The head of each... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  18. 44 CFR 18.600 - Semi-annual compilation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 44 Emergency Management and Assistance 1 2012-10-01 2011-10-01 true Semi-annual compilation. 18... OF HOMELAND SECURITY GENERAL NEW RESTRICTIONS ON LOBBYING Agency Reports § 18.600 Semi-annual... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  19. 24 CFR 87.600 - Semi-annual compilation.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 1 2013-04-01 2013-04-01 false Semi-annual compilation. 87.600... Development NEW RESTRICTIONS ON LOBBYING Agency Reports § 87.600 Semi-annual compilation. (a) The head of each... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  20. 38 CFR 45.600 - Semi-annual compilation.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2013-07-01 2013-07-01 false Semi-annual compilation... (CONTINUED) NEW RESTRICTIONS ON LOBBYING Agency Reports § 45.600 Semi-annual compilation. (a) The head of... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  1. 22 CFR 138.600 - Semi-annual compilation.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Semi-annual compilation. 138.600 Section 138... § 138.600 Semi-annual compilation. (a) The head of each agency shall collect and compile the disclosure... information shall not be available for public inspection. (e) The first semi-annual compilation shall...

  2. 7 CFR 3018.600 - Semi-annual compilation.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 15 2011-01-01 2011-01-01 false Semi-annual compilation. 3018.600 Section 3018.600..., DEPARTMENT OF AGRICULTURE NEW RESTRICTIONS ON LOBBYING Agency Reports § 3018.600 Semi-annual compilation. (a... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  3. 22 CFR 311.600 - Semi-annual compilation.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 2 2012-04-01 2009-04-01 true Semi-annual compilation. 311.600 Section 311.600 Foreign Relations PEACE CORPS NEW RESTRICTIONS ON LOBBYING Agency Reports § 311.600 Semi-annual... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  4. 29 CFR 93.600 - Semi-annual compilation.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 1 2011-07-01 2011-07-01 false Semi-annual compilation. 93.600 Section 93.600 Labor Office of the Secretary of Labor NEW RESTRICTIONS ON LOBBYING Agency Reports § 93.600 Semi-annual... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  5. 41 CFR 105-69.600 - Semi-annual compilation.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false Semi-annual compilation... Administration 69-NEW RESTRICTIONS ON LOBBYING Agency Reports § 105-69.600 Semi-annual compilation. (a) The head... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  6. 20 CFR 438.600 - Semi-annual compilation.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Semi-annual compilation. 438.600 Section 438....600 Semi-annual compilation. (a) The Commissioner of Social Security will collect and compile the... semi-annual compilation was submitted on May 31, 1990, and contains a compilation of the...

  7. 41 CFR 105-69.600 - Semi-annual compilation.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 41 Public Contracts and Property Management 3 2012-01-01 2012-01-01 false Semi-annual compilation... Administration 69-NEW RESTRICTIONS ON LOBBYING Agency Reports § 105-69.600 Semi-annual compilation. (a) The head... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  8. 40 CFR 34.600 - Semi-annual compilation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Semi-annual compilation. 34.600 Section... NEW RESTRICTIONS ON LOBBYING Agency Reports § 34.600 Semi-annual compilation. (a) The head of each... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  9. 29 CFR 93.600 - Semi-annual compilation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Semi-annual compilation. 93.600 Section 93.600 Labor Office of the Secretary of Labor NEW RESTRICTIONS ON LOBBYING Agency Reports § 93.600 Semi-annual... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  10. 40 CFR 34.600 - Semi-annual compilation.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Semi-annual compilation. 34.600 Section... NEW RESTRICTIONS ON LOBBYING Agency Reports § 34.600 Semi-annual compilation. (a) The head of each... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  11. 20 CFR 438.600 - Semi-annual compilation.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Semi-annual compilation. 438.600 Section 438....600 Semi-annual compilation. (a) The Commissioner of Social Security will collect and compile the... semi-annual compilation was submitted on May 31, 1990, and contains a compilation of the...

  12. 10 CFR 601.600 - Semi-annual compilation.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false Semi-annual compilation. 601.600 Section 601.600 Energy... Semi-annual compilation. (a) The head of each agency shall collect and compile the disclosure reports... information shall not be available for public inspection. (e) The first semi-annual compilation shall...

  13. 49 CFR 20.600 - Semi-annual compilation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 1 2014-10-01 2014-10-01 false Semi-annual compilation. 20.600 Section 20.600... Semi-annual compilation. (a) The head of each agency shall collect and compile the disclosure reports... information shall not be available for public inspection. (e) The first semi-annual compilation shall...

  14. 22 CFR 138.600 - Semi-annual compilation.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Semi-annual compilation. 138.600 Section 138... § 138.600 Semi-annual compilation. (a) The head of each agency shall collect and compile the disclosure... information shall not be available for public inspection. (e) The first semi-annual compilation shall...

  15. 41 CFR 105-69.600 - Semi-annual compilation.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false Semi-annual compilation... Administration 69-NEW RESTRICTIONS ON LOBBYING Agency Reports § 105-69.600 Semi-annual compilation. (a) The head... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  16. 29 CFR 93.600 - Semi-annual compilation.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 1 2014-07-01 2013-07-01 true Semi-annual compilation. 93.600 Section 93.600 Labor Office of the Secretary of Labor NEW RESTRICTIONS ON LOBBYING Agency Reports § 93.600 Semi-annual... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  17. 45 CFR 604.600 - Semi-annual compilation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 3 2014-10-01 2014-10-01 false Semi-annual compilation. 604.600 Section 604.600... RESTRICTIONS ON LOBBYING Agency Reports § 604.600 Semi-annual compilation. (a) The head of each agency shall... first semi-annual compilation shall be submitted on May 31, 1990, and shall contain a compilation of...

  18. 38 CFR 45.600 - Semi-annual compilation.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2014-07-01 2014-07-01 false Semi-annual compilation... (CONTINUED) NEW RESTRICTIONS ON LOBBYING Agency Reports § 45.600 Semi-annual compilation. (a) The head of... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  19. 22 CFR 227.600 - Semi-annual compilation.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Semi-annual compilation. 227.600 Section 227... § 227.600 Semi-annual compilation. (a) The head of each agency shall collect and compile the disclosure... information shall not be available for public inspection. (e) The first semi-annual compilation shall...

  20. 44 CFR 18.600 - Semi-annual compilation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 44 Emergency Management and Assistance 1 2014-10-01 2014-10-01 false Semi-annual compilation. 18... OF HOMELAND SECURITY GENERAL NEW RESTRICTIONS ON LOBBYING Agency Reports § 18.600 Semi-annual... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  1. 22 CFR 311.600 - Semi-annual compilation.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 2 2014-04-01 2014-04-01 false Semi-annual compilation. 311.600 Section 311.600 Foreign Relations PEACE CORPS NEW RESTRICTIONS ON LOBBYING Agency Reports § 311.600 Semi-annual... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  2. 7 CFR 3018.600 - Semi-annual compilation.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 15 2014-01-01 2014-01-01 false Semi-annual compilation. 3018.600 Section 3018.600..., DEPARTMENT OF AGRICULTURE NEW RESTRICTIONS ON LOBBYING Agency Reports § 3018.600 Semi-annual compilation. (a... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  3. 24 CFR 87.600 - Semi-annual compilation.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 1 2014-04-01 2014-04-01 false Semi-annual compilation. 87.600... Development NEW RESTRICTIONS ON LOBBYING Agency Reports § 87.600 Semi-annual compilation. (a) The head of each... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  4. 45 CFR 93.600 - Semi-annual compilation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 1 2014-10-01 2014-10-01 false Semi-annual compilation. 93.600 Section 93.600... LOBBYING Agency Reports § 93.600 Semi-annual compilation. (a) The head of each agency shall collect and... first semi-annual compilation shall be submitted on May 31, 1990, and shall contain a compilation of...

  5. 34 CFR 82.600 - Semi-annual compilation.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 1 2014-07-01 2014-07-01 false Semi-annual compilation. 82.600 Section 82.600....600 Semi-annual compilation. (a) The head of each agency shall collect and compile the disclosure... information shall not be available for public inspection. (e) The first semi-annual compilation shall...

  6. 22 CFR 519.600 - Semi-annual compilation.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 2 2014-04-01 2014-04-01 false Semi-annual compilation. 519.600 Section 519... § 519.600 Semi-annual compilation. (a) The head of each agency shall collect and compile the disclosure... information shall not be available for public inspection. (e) The first semi-annual compilation shall...

  7. 45 CFR 1158.600 - Semi-annual compilation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 3 2014-10-01 2014-10-01 false Semi-annual compilation. 1158.600 Section 1158.600... HUMANITIES NATIONAL ENDOWMENT FOR THE ARTS NEW RESTRICTIONS ON LOBBYING Agency Reports § 1158.600 Semi-annual... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  8. 32 CFR 28.600 - Semi-annual compilation.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 1 2014-07-01 2014-07-01 false Semi-annual compilation. 28.600 Section 28.600... REGULATIONS NEW RESTRICTIONS ON LOBBYING Agency Reports § 28.600 Semi-annual compilation. (a) The head of each... available for public inspection. (e) The first semi-annual compilation shall be submitted on May 31,...

  9. 32 CFR 70.11 - DoD semiannual report.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 1 2012-07-01 2012-07-01 false DoD semiannual report. 70.11 Section 70.11... DISCHARGE REVIEW BOARD (DRB) PROCEDURES AND STANDARDS § 70.11 DoD semiannual report. (a) Semiannual reports... 1 through March 31 and April 1 through September 30). (b) The reporting period will be...

  10. 32 CFR 70.11 - DoD semiannual report.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 1 2011-07-01 2011-07-01 false DoD semiannual report. 70.11 Section 70.11... DISCHARGE REVIEW BOARD (DRB) PROCEDURES AND STANDARDS § 70.11 DoD semiannual report. (a) Semiannual reports... 1 through March 31 and April 1 through September 30). (b) The reporting period will be...

  11. Solution-processed small-molecule solar cells: breaking the 10% power conversion efficiency.

    PubMed

    Liu, Yongsheng; Chen, Chun-Chao; Hong, Ziruo; Gao, Jing; Yang, Yang Michael; Zhou, Huanping; Dou, Letian; Li, Gang; Yang, Yang

    2013-01-01

    A two-dimensional conjugated small molecule (SMPV1) was designed and synthesized for high performance solution-processed organic solar cells. This study explores the photovoltaic properties of this molecule as a donor, with a fullerene derivative as an acceptor, using solution processing in single junction and double junction tandem solar cells. The single junction solar cells based on SMPV1 exhibited a certified power conversion efficiency of 8.02% under AM 1.5 G irradiation (100 mW cm(-2)). A homo-tandem solar cell based on SMPV1 was constructed with a novel interlayer (or tunnel junction) consisting of bilayer conjugated polyelectrolyte, demonstrating an unprecedented PCE of 10.1%. These results strongly suggest solution-processed small molecular materials are excellent candidates for organic solar cells. PMID:24285006

  12. Information entropy of activation process: Application for low-temperature fluctuations of a myoglobin molecule

    NASA Astrophysics Data System (ADS)

    Stepanov, A. V.

    2015-11-01

    Activation process for unimolecular reaction has been considered by means of radiation theory. The formulae of information entropy of activation have been derived for the Boltzmann-Arrhenius model and the activation process model (APM). The physical meaning of this entropy has been determined. It is a measure of conversion of thermal radiation energy to mechanical energy that moves atoms in a molecule during elementary activation act. It is also a measure of uncertainty of this energy conversion. The uncertainty is due to unevenness of distribution function representing the activation process. It has been shown that Arrhenius dependence is caused by the entropy change. Efficiency comparison of the two models under consideration for low-temperature fluctuations of a myoglobin molecule structure shows that the APM should be favored over the Boltzmann-Arrhenius one.

  13. Low-rank coal research semiannual report, January 1992--June 1992

    SciTech Connect

    Not Available

    1992-12-31

    This semiannual report is a compilation of seventeen reports on ongoing coal research at the University of North Dakota. The following research areas are covered: control technology and coal preparation; advanced research and technology development; combustion; liquefaction and gasification. Individual papers have been processed separately for inclusion in the Energy Science and Technology Database.

  14. Theoretical model for the latitude dependence of the thermospheric annual and semiannual variations

    NASA Technical Reports Server (NTRS)

    Mayr, H. G.; Volland, H.

    1972-01-01

    A three-dimensional model for the annual and semiannual variations of the thermosphere is presented in which energy and diffusive mass transport associated with the global circulation are considered in a self-consistent form. It is shown that these processes play a major role in the thermosphere dynamics and account for a number of temperature and compositional phenomena.

  15. TIPS-DBC small molecule O-FETs fabricated by evaporation and solution processing

    NASA Astrophysics Data System (ADS)

    Gruszecki, Daniel; Singh, Birendra; Bown, Mark; Lewis, David

    2012-02-01

    The performance of organic field effect transistors using the small molecule, tri-isopropyl- silane-di-benzo chrysene (TIPS-DBC) is reported. The field effect mobility μFE is found to depend on the deposition conditions, which affect the morphology of the film. A mobility in the range of 1.5 × 10-6 to 2.4 × 10-4 cm2 V-1 s-1 is obtained from the evaporated films depending on the substrate treatment and deposition temperature, while films deposited by solution-processing techniques yield mobilities in the range of 0.7 × 10-3 to 1.5 × 10-3 cm2 V-1 s-1. The enhanced performance in polycrystalline solution-processed coatings and its relationship to crystallite size is an important parameter in the design of high-performance devices based on small molecules.

  16. [Evaluation of high-efficiency gas-liquid contactors for natural gas processing]. Semiannual technical progress report, October 1, 1992--March 31, 1993

    SciTech Connect

    Not Available

    1993-12-01

    The objective of this proposed program is to evaluate the potential of rotating gas-liquid contactors for natural gas processing by expanding the currently available database. This expansion will focus on application of this technology to environments representative of those typically encountered in natural gas processing plants. Operational and reliability concerns will be addressed while generating pertinent engineering data relating to the mass-transfer process. This report presents results on fluid dynamics and mass transfer coefficient studies.

  17. Testing Landscape Theory for Biomolecular Processes with Single Molecule Fluorescence Spectroscopy

    NASA Astrophysics Data System (ADS)

    Truex, Katherine; Chung, Hoi Sung; Louis, John M.; Eaton, William A.

    2015-07-01

    Although Kramers' theory for diffusive barrier crossing on a 1D free energy profile plays a central role in landscape theory for complex biomolecular processes, it has not yet been rigorously tested by experiment. Here we test this 1D diffusion scenario with single molecule fluorescence measurements of DNA hairpin folding. We find an upper bound of 2.5 μ s for the average transition path time, consistent with the predictions by theory with parameters determined from optical tweezer measurements.

  18. Formation and Destruction Processes of Interstellar Dust: From Organic Molecules to carbonaceous Grains

    NASA Technical Reports Server (NTRS)

    Salama, F.; Biennier, L.

    2004-01-01

    The study of the formation and destruction processes of cosmic dust is essential to understand and to quantify the budget of extraterrestrial organic molecules. interstellar dust presents a continuous size distribution from large molecules, radicals and ions to nanometer-sized particles to micron-sized grains. The lower end of the dust size distribution is thought to be responsible for the ubiquitous spectral features that are seen in emission in the IR (UIBs) and in absorption in the visible (DIBs). The higher end of the dust-size distribution is thought to be responsible for the continuum emission plateau that is seen in the IR and for the strong absorption seen in the interstellar UV extinction curve. All these spectral signatures are characteristic of cosmic organic materials that are ubiquitous and present in various forms from gas-phase molecules to solid-state grains. Although dust with all its components plays an important role in the evolution of interstellar chemistry and in the formation of organic molecules, little is known on the formation and destruction processes of dust. Recent space observations in the UV (HST) and in the IR (ISO) help place size constraints on the molecular component of carbonaceous IS dust and indicate that small (ie., subnanometer) PAHs cannot contribute significantly to the IS features in the UV and in the IR. Studies of large molecular and nano-sized IS dust analogs formed from PAH precursors have been performed in our laboratory under conditions that simulate diffuse ISM environments (the particles are cold -100 K vibrational energy, isolated in the gas phase and exposed to a high-energy discharge environment in a cold plasma). The species (molecules, molecular fragments, ions, nanoparticles, etc) formed in the pulsed discharge nozzle (PDN) plasma source are detected with a high-sensitivity cavity ring-down spectrometer (CRDS). We will present new experimental results that indicate that nanoparticles are generated in the

  19. Gaussian process model for extrapolation of scattering observables for complex molecules: From benzene to benzonitrile

    SciTech Connect

    Cui, Jie; Krems, Roman V.; Li, Zhiying

    2015-10-21

    We consider a problem of extrapolating the collision properties of a large polyatomic molecule A–H to make predictions of the dynamical properties for another molecule related to A–H by the substitution of the H atom with a small molecular group X, without explicitly computing the potential energy surface for A–X. We assume that the effect of the −H →−X substitution is embodied in a multidimensional function with unknown parameters characterizing the change of the potential energy surface. We propose to apply the Gaussian Process model to determine the dependence of the dynamical observables on the unknown parameters. This can be used to produce an interval of the observable values which corresponds to physical variations of the potential parameters. We show that the Gaussian Process model combined with classical trajectory calculations can be used to obtain the dependence of the cross sections for collisions of C{sub 6}H{sub 5}CN with He on the unknown parameters describing the interaction of the He atom with the CN fragment of the molecule. The unknown parameters are then varied within physically reasonable ranges to produce a prediction uncertainty of the cross sections. The results are normalized to the cross sections for He — C{sub 6}H{sub 6} collisions obtained from quantum scattering calculations in order to provide a prediction interval of the thermally averaged cross sections for collisions of C{sub 6}H{sub 5}CN with He.

  20. Multiscale Molecular Simulation of Solution Processing of SMDPPEH: PCBM Small-Molecule Organic Solar Cells.

    PubMed

    Lee, Cheng-Kuang; Pao, Chun-Wei

    2016-08-17

    Solution-processed small-molecule organic solar cells are a promising renewable energy source because of their low production cost, mechanical flexibility, and light weight relative to their pure inorganic counterparts. In this work, we developed a coarse-grained (CG) Gay-Berne ellipsoid molecular simulation model based on atomistic trajectories from all-atom molecular dynamics simulations of smaller system sizes to systematically study the nanomorphology of the SMDPPEH/PCBM/solvent ternary blend during solution processing, including the blade-coating process by applying external shear to the solution. With the significantly reduced overall system degrees of freedom and computational acceleration from GPU, we were able to go well beyond the limitation of conventional all-atom molecular simulations with a system size on the order of hundreds of nanometers with mesoscale molecular detail. Our simulations indicate that, similar to polymer solar cells, the optimal blending ratio in small-molecule organic solar cells must provide the highest specific interfacial area for efficient exciton dissociation, while retaining balanced hole/electron transport pathway percolation. We also reveal that blade-coating processes have a significant impact on nanomorphology. For given donor/acceptor blending ratios, applying an external shear force can effectively promote donor/acceptor phase segregation and stacking in the SMDPPEH domains. The present study demonstrated the capability of an ellipsoid-based coarse-grained model for studying the nanomorphology evolution of small-molecule organic solar cells during solution processing/blade-coating and provided links between fabrication protocols and device nanomorphologies. PMID:27435212

  1. Electronic excitations in solution-processed oligothiophene small-molecules for organic solar cells

    NASA Astrophysics Data System (ADS)

    Gala, F.; Mattiello, L.; Brunetti, F.; Zollo, G.

    2016-02-01

    First principles calculations based on density functional theory and many body perturbation theory have been employed to study the optical absorption properties of a newly synthesized oligo-thiophene molecule, with a quaterthiophene central unit, that has been designed for solution-processed bulk-heterojunction solar cells. To this aim we have employed the GW approach to obtain quasiparticle energies as a pre-requisite to solve the Bethe-Salpeter equation for the excitonic Hamiltonian. We show that the experimental absorption spectrum can be explained only by taking into account the inter-molecular transitions among the π-stacked poly-conjugated molecules that are typically obtained in solid-state organic samples.

  2. The effect of gold nanoparticles on exchange processes in collision complexes of triplet and singlet oxygen molecules with excited eosin molecules

    NASA Astrophysics Data System (ADS)

    Bryukhanov, V. V.; Minaev, B. M.; Tsibul'nikova, A. V.; Slezhkin, V. A.

    2015-07-01

    We have studied exchange processes in contact complexes of triplet eosin molecules with oxygen molecules in the triplet (3Σ{/g -}) and singlet (1Δ g ) states in thin polyvinylbutyral films in the presence of gold nanoparticles. Upon resonant excitation of surface plasmons in gold nanoparticles into the absorption band of eosin molecules-singlet oxygen sensitizers-we have obtained an increase in the intensity of the delayed fluorescence and an increase in the lifetime of the dye with simultaneous quenching of the luminescence of singlet oxygen. The kinetics of the delayed fluorescence of the dye as a result of singlet-triplet annihilation of triplet eosin molecules with singlet oxygen molecules has been investigated. To compare theoretical and experimental data, we have numerically simulated energy transfer processes. Rate constants of energy transfer and of singlet-triplet annihilation, as well as quenching constants of triplet states of the dye by molecular oxygen, have been calculated. Luminescence quantum yield 1Δ g of polyvinylbutyral has been estimated. We have analyzed quantum-chemically electronic mechanisms of singlet-triplet annihilation of oxygen and eosin.

  3. Development of an `intelligent grinding wheel` for in-process monitoring of ceramic grinding. Semi-annual report No. 2, March 1, 1997--August 31, 1997

    SciTech Connect

    Malkin, S.; Gao, R.; Guo, C.; Varghese, B.; Pathare, S.

    1997-09-29

    The overall objective of this project is to develop sensor-integrated `intelligent` diamond wheels for grinding ceramics. Such wheels will be `smart` enough to monitor and supervise both the wheel preparation and grinding processes without the need to instrument the machine tool. Intelligent wheels will utilize re-useable cores integrated with two types of sensors: acoustic emission (AE) and dynamic force transducers. Signals from the sensors will be transmitted from a rotating wheel to a receiver by telemetry. Intelligent wheels will be `trained` to recognize distinct characteristics associated with truing, dressing and grinding.

  4. Molecule formation and infrared emission in fast interstellar shocks. I Physical processes

    NASA Technical Reports Server (NTRS)

    Hollenbach, D.; Mckee, C. F.

    1979-01-01

    The paper analyzes the structure of fast shocks incident upon interstellar gas of ambient density from 10 to the 7th per cu cm, while focusing on the problems of formation and destruction of molecules and infrared emission in the cooling, neutral post shock gas. It is noted that such fast shocks initially dissociate almost all preexisting molecules. Discussion covers the physical processes which determine the post shock structure between 10 to the 4 and 10 to the 2 K. It is shown that the chemistry of important molecular coolants H2, CO, OH, and H2O, as well as HD and CH, is reduced to a relatively small set of gas phase and grain surface reactions. Also, the chemistry follows the slow conversion of atomic hydrogen into H2, which primarily occurs on grain surfaces. The dependence of this H2 formation rate on grain and gas temperatures is examined and the survival of grains behind fast shocks is discussed. Post shock heating and cooling rates are calculated and an appropriate, analytic, universal cooling function is developed for molecules other than hydrogen which includes opacities from both the dust and the lines.

  5. Characteristics of the Johari-Goldstein process in rigid asymmetric molecules.

    PubMed

    Fragiadakis, D; Roland, C M

    2013-10-01

    Molecular dynamics simulations were carried out on a Lennard-Jones binary mixture of rigid (fixed bond length) diatomic molecules. The translational and rotational correlation functions, and the corresponding susceptibilities, exhibit two relaxation processes: the slow structural relaxation (α dynamics) and a higher frequency secondary relaxation. The latter is a Johari-Goldstein (JG) process, by its definition of involving all parts of the molecule. It shows several properties characteristic of the JG relaxation: (1) merging with the α relaxation at high temperature; (2) a change in temperature dependence of its relaxation strength on vitrification; (3) a separation in frequency from the α peak that correlates with the breadth of the α dispersion; and (4) sensitivity to volume, pressure, and physical aging. These properties can be used to determine whether a secondary relaxation in a real material is an authentic JG process, rather than more trivial motion involving intramolecular degrees of freedom. The latter has no connection to the glass transition, whereas the JG relaxation is closely related to structural relaxation, and thus can provide new insights into the phenomenon. PMID:24229172

  6. Monitoring peptide processing for MHC class I molecules in the endoplasmic reticulum.

    PubMed

    Shastri, Nilabh; Nagarajan, Niranjana; Lind, Kristin C; Kanaseki, Takayuki

    2014-02-01

    Classical MHC class I molecules open a window into the cell by presenting intracellular peptides (pMHC I) on the surface. The peptides are used for immune surveillance by circulating CD8+ T and NK cells to detect and eliminate infected or tumor cells. Not surprisingly, viruses and tumor cells have evolved immune evasion mechanisms to keep the window shades down and the cytotoxic cells oblivious to their presence. Here, we review counter mechanisms that nevertheless allow the immune system to detect and eliminate cells unable to properly process antigenic peptides in the endoplasmic reticulum. PMID:24556408

  7. Development of an ``intelligent grinding wheel`` for in-process monitoring of ceramic grinding. Semi-annual report {number_sign}4

    SciTech Connect

    Malkin, S.; Gao, R.; Guo, C.; Varghese, B.; Pathare, S.

    1998-09-30

    The overall objective of this project is to develop sensor-integrated ``intelligent`` diamond wheels for grinding of ceramics. Such wheels will be ``smart`` enough to monitor and supervise both the wheel preparation and grinding processes without the need to instrument the machine tool. Intelligent wheels will utilize re-useable cores integrated with sensors: to measure the acoustic emission (AE) and grinding force. Signals from the sensors will be transmitted from a rotating wheel to a receiver by telemetry. Wheels will be ``trained`` to recognize distinct characteristics associated with truing, dressing and grinding. This overall project is divided into six tasks as follows: (1) development of miniaturized sensors and data transmission system; (2) wheel design and sensor configuration; (3) calibration of the sensor integrated wheel; (4) training of the intelligent wheel; (5) grinding tests; and (6) prototype demonstration. The technical progress is summarized in this report according to the tasks. All activity during this period has been concerned with the first two interrelated tasks, which need to be completed before undertaking the remaining tasks.

  8. 76 FR 40136 - Semiannual Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-07

    ... FR 79864. The semiannual agenda of the SBA conforms to the Unified Agenda format developed by the... agencies; and revising the definitions of some terms. Timetable: Action Date FR Cite NPRM 08/00/11... agencies; and revising the definitions of some terms. Timetable: Action Date FR Cite NPRM...

  9. 77 FR 8020 - Semiannual Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-13

    ... Agenda for the agency. SBA's last semiannual regulatory agenda was published on July 7, 2011, at 76 FR... Administration--Completed Actions Regulation Sequence No. Title Identifier No. 474 Implementation of Military... individual SBDC client data. Timetable: Action Date FR Cite ANPRM 06/00/12 Regulatory Flexibility...

  10. 12 CFR 8.2 - Semiannual assessment.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... computed at the same rate as provided in the Table in 12 CFR 8.2(a); however, only the total domestic... 12 Banks and Banking 1 2014-01-01 2014-01-01 false Semiannual assessment. 8.2 Section 8.2 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY ASSESSMENT OF FEES §...

  11. 12 CFR 8.2 - Semiannual assessment.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... the Table in 12 CFR 8.2(a); however, only the total domestic assets of the Federal branch or Federal... 12 Banks and Banking 1 2011-01-01 2011-01-01 false Semiannual assessment. 8.2 Section 8.2 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY ASSESSMENT OF FEES §...

  12. 12 CFR 8.2 - Semiannual assessment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... the Table in 12 CFR 8.2(a); however, only the total domestic assets of the Federal branch or Federal... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Semiannual assessment. 8.2 Section 8.2 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY ASSESSMENT OF FEES §...

  13. Securities and Exchange Commission Semiannual Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-20

    ... [The Regulatory Plan and Unified Agenda of Federal Regulatory and Deregulatory Actions] Part XXIV Securities and Exchange Commission Semiannual Regulatory Agenda ] SECURITIES AND EXCHANGE COMMISSION (SEC) SECURITIES AND EXCHANGE COMMISSION 17 CFR Ch. II Regulatory Flexibility Agenda AGENCY: Securities and Exchange Commission. ACTION:...

  14. Nuclear Regulatory Commission Semiannual Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-20

    ...) 2010, less the amounts appropriated from the Nuclear Waste Fund, amounts appropriated for Waste... agenda on April 26, 2010 (75 FR 21960). For this edition of the NRC's regulatory agenda, the most... publication of the last NRC semiannual agenda on April 26, 2010 (75 FR 21960). Within each group, the...

  15. Nuclear Regulatory Commission Semiannual Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-26

    ... amounts appropriated from the Nuclear Waste Fund, amounts appropriated for Waste Incidental to... December 7, 2009 (74 FR 64572). ADDRESSES: Comments on any rule in the agenda may be sent to the Secretary... occurred on rules since publication of the last NRC semiannual agenda on December 7, 2009 (74 FR...

  16. Department of Commerce Semiannual Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-20

    ... [The Regulatory Plan and Unified Agenda of Federal Regulatory and Deregulatory Actions] Part IV Department of Commerce Semiannual Regulatory Agenda ] DEPARTMENT OF COMMERCE (DOC) DEPARTMENT OF COMMERCE Office of the Secretary 13 CFR Ch. III 15 CFR Subtitle A; Subtitle B, Chs. I, II, III, VII, VIII, IX, and XI 19 CFR Ch. III 37 CFR Chs. I, IV,...

  17. 78 FR 1636 - Semiannual Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-08

    ...This Regulatory Agenda is a semiannual summary of all current and projected rulemakings, existing regulations, and completed actions of the Small Business Administration (SBA). For this fall edition of the SBA's Regulatory Agenda, a Regulatory Plan that contains a list of the Agency's most important and significant regulatory actions and a Statement of Regulatory Priorities is also included.......

  18. 78 FR 44331 - Semiannual Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-23

    ...This Regulatory Agenda is a semiannual summary of all current and projected rulemakings and completed actions of the Small Business Administration (SBA). SBA expects that this summary information will enable the public to be more aware of, and effectively participate in, SBA's regulatory activity. SBA invites the public to submit comments on any aspect of this...

  19. 78 FR 44247 - Semiannual Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-23

    ... measuring ice maker energy use. Timetable: Action Date FR Cite NPRM 07/00/13 Final Action 07/00/14..., Office of Building Technologies Program, EE-2J, Department of Energy, Energy Efficiency and Renewable... July 23, 2013 Part VII Department of Energy Semiannual Regulatory Agenda #0;#0;Federal Register /...

  20. Department of Interior Semiannual Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-26

    ...: Action Date FR Cite Final Action 04/00/10 Regulatory Flexibility Analysis Required: Yes Agency Contact... idle facilities. Timetable: Action Date FR Cite NPRM 12/00/10 NPRM Comment Period End 02/00/11... Part IX Department of the Interior Semiannual Regulatory Agenda ] DEPARTMENT OF THE INTERIOR...

  1. Environmental Protection Agency Semiannual Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-26

    ...:// Not in FR www.epa.gov/lawsregs/search/regagenda.html Semiannual Regulatory Flexibility Agenda www....html issue ] Monthly Action Initiation List http://www.regulations.gov/fdmspublic/component/ Not in FR... Rulemaking Gateway www.epa.gov/rulemaking/ Not in FR B. What Are EPA's Regulatory Goals, and What...

  2. Patterns and processes in microbial biogeography: do molecules and morphologies give the same answers?

    PubMed

    Santoferrara, Luciana F; Grattepanche, Jean-David; Katz, Laura A; McManus, George B

    2016-07-01

    Our knowledge on microbial biogeography depends on the way we define and study diversity. In contrast to most microbes, some protist lineages have conspicuous structures that allow comparisons of diversity concepts and measures-those based on molecules and those based on morphology. We analyzed a group of shell-bearing planktonic ciliates, the tintinnids, in a coast-to-ocean gradient using high-throughput sequencing and microscopy. First, we compared molecular operational taxonomic units (OTUs) and morphospecies in terms of assemblage composition, distribution and relationships with the environment. OTUs revealed potentially novel and rare taxa, while morphospecies showed clearer correlations with environmental factors, and both approaches coincided in supporting a coastal versus oceanic pattern. Second, we explored which processes influence assembly across the environmental gradient examined. Assemblage fluctuations were associated with significant distance-decay and changes in morphospecies size and prey proxies, thus suggesting niche partitioning as a key structuring mechanism. Our conclusion is that molecules and morphologies generally agreed, but they provided complementary data, the first revealing hidden diversity, and the latter making better connections between distribution patterns and ecological processes. This highlights the importance of linking genotypes and phenotypes (using multidisciplinary analyses and/or reliable databases of barcoded species), to understand the diversity, biogeography and ecological roles of microbes. PMID:26849313

  3. A modular molecular framework for utility in small-molecule solution-processed organic photovoltaic devices

    SciTech Connect

    Welch, Gregory C.; Perez, Louis A.; Hoven, Corey V.; Zhang, Yuan; Dang, Xuan-Dung; Sharenko, Alexander; Toney, Michael F.; Kramer, Edward J.; Nguyen, Thuc-Quyen; Bazan, Guillermo C.

    2011-07-22

    We report on the design, synthesis and characterization of light harvesting small molecules for use in solution-processed small molecule bulk heterojunction (SM-BHJ) solar cell devices. These molecular materials are based upon an acceptor/donor/acceptor (A/D/A) core with donor endcapping units. Utilization of a dithieno(3,2-b;2',3'-d)silole (DTS) donor and pyridal[2,1,3]thiadiazole (PT) acceptor leads to strong charge transfer characteristics, resulting in broad optical absorption spectra extending well beyond 700 nm. SM-BHJ solar cell devices fabricated with the specific example 5,5'-bis{7-(4-(5-hexylthiophen-2-yl)thiophen-2-yl)-[1,2,5]thiadiazolo[3,4-c]pyridine}-3,3'-di-2-ethylhexylsilylene-2,2'-bithiophene (6) as the donor and [6,6]-phenyl-C71-butyric acid methyl ester (PC71BM) as the acceptor component showed short circuit currents above -10 mA cm-2 and power conversion efficiencies (PCEs) over 3%. Thermal processing is a critical factor in obtaining favorable active layer morphologies and high PCE values. A combination of UV-visible spectroscopy, conductive and photo-conductive atomic force microscopies, dynamic secondary mass ion spectrometry (DSIMS), and grazing incident wide angle X-ray scattering (GIWAXS) experiments were carried out to characterize how thermal treatment influences the active layer structure and organization.

  4. Understanding the morphology of solution processed fullerene-free small molecule bulk heterojunction blends.

    PubMed

    Namepetra, Andrew; Kitching, Elizabeth; Eftaiha, Ala'a F; Hill, Ian G; Welch, Gregory C

    2016-05-14

    Bulk-heterojunction (BHJ) molecular blends prepared from small molecules based on diketopyrrolopyrrole (DPP) and perylene-diimide (PDI) chromophores have been studied using optical absorption, cyclic voltammetry, photoluminescence quenching, X-ray diffraction, atomic force microscopy, and current-voltage measurements. The results provided useful insights into the use of DPP and PDI based molecules as donor-acceptor composites for organic photovoltaic (OPV) applications. Beside optoelectronic compatibility, the choice of active layer processing conditions is of key importance to improve the performance of BHJ solar cells. In this context, post-production treatments, viz. thermal and solvent vapour annealing, and the use of 1,8-diiodooctane as a solvent additive were employed to optimize the morphology of blend films. X-ray diffraction and atomic force microscopy indicated that the aforementioned processing strategies led to non-optimal composite morphologies with significantly large crystallites in comparison to exciton diffusion lengths. Although the open circuit voltage of the OPV devices was satisfactory (0.78 V), it was anticipated that the bulky domains hamper charge dissociation and transport, which resulted in low photovoltaic performance. PMID:27087259

  5. Defects in solution-processed dithienylsilole-based small-molecule photovoltaic thin-films

    NASA Astrophysics Data System (ADS)

    Muntasir, Tanvir; Chaudhary, Sumit

    2016-01-01

    DTS-(FBTTh2)2 is a prominent solution-processable small-molecule donor for donor-acceptor bulk-heterojunction organic photovoltaics. Power conversion efficiency of DTS-(FBTTh2)2 based photovoltaic devices exceeds 8%. This paper reports on the distribution of sub-bandgap trap states in DTS-(FBTTh2)2. Trap states were probed using admittance spectroscopy and low-frequency capacitance-voltage profiling and analyzed using established theoretical models. Three distributions were revealed in the trap density of states energy spectra. Key observations were (1) thicker solution-processed films with higher drying time had 55% less traps than thinner films that dried relative faster (2) blending of DTS-(FBTTh2)2 with the acceptor PC70BM introduced traps at the center of the donor-acceptor interfacial bandgap. Charge carrier dynamics in DTS-(FBTTh2)2 based thin-films was also characterized using impedance spectroscopy.

  6. 32 CFR 70.11 - DoD semiannual report.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 1 2013-07-01 2013-07-01 false DoD semiannual report. 70.11 Section 70.11 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE PERSONNEL, MILITARY AND CIVILIAN DISCHARGE REVIEW BOARD (DRB) PROCEDURES AND STANDARDS § 70.11 DoD semiannual report. (a) Semiannual reports will be submitted by the 20th of...

  7. Mechanical Properties of Solution-Processed Small-Molecule Semiconductor Films.

    PubMed

    Rodriquez, Daniel; Savagatrup, Suchol; Valle, Eduardo; Proctor, Christopher M; McDowell, Caitlin; Bazan, Guillermo C; Nguyen, Thuc-Quyen; Lipomi, Darren J

    2016-05-11

    Advantages of semiconducting small molecules-as opposed to semiconducting polymers-include synthetic simplicity, monodispersity, low cost, and ease of purification. One purported disadvantage of small-molecule films is reduced mechanical robustness. This paper measures the tensile modulus and crack-onset strain for pure films of the high-performance solution-processable small-molecule donors 7,7'-[4,4-bis(2-ethylhexyl)-4H-silolo[3,2-b:4,5-b']dithiophene-2,6-diyl]bis[6-fluoro-4-(5'-hexyl-[2,2'-bithiophen]-5-yl)benzo[c][1,2,5]thiadiazole] (DTS(FBTTh2)2), 2,5-di(2-ethylhexyl)-3,6-bis(5″-n-hexyl-[2,2',5',2″]terthiophen-5-yl)-pyrrolo[3,4-c]pyrrole-1,4-dione (SMDPPEH), and 6,13-bis(triisopropylsilylethynyl)pentacene (TIPS-pentacene), the acceptor 5,5'-(2,1,3-benzothiadiazole-4,7-diyldi-2,1-ethenediyl)bis[2-hexyl-1H-isoindole-1,3(2H)-dione] (HPI-BT), blends of DTS(FBTTh2)2 and SMDPPEH with [6,6]-phenyl C71 butyric acid methyl ester (PC71BM) and with HPI-BT, and bulk heterojunction films processed with the additives 1,8-diiodooctane (DIO) and polystyrene (PS). The most deformable films of solution-processed organic semiconductors are found to exhibit tensile moduli and crack-onset strains comparable to those measured for conjugated polymers. For example, the tensile modulus of as-cast DTS(FBTTh2)2 is 0.68 GPa (i.e., comparable to poly(3-hexylthiophene) (P3HT), the common polymer), while it exhibits no cracks when stretched on an elastomeric substrate to strains of 14%. While this high degree of stretchability is lost upon the addition of PC71BM (4.2 GPa, 1.42%), it can be partially recovered using processing additives. Tensile modulus and crack-onset strain are highly correlated, which is typical of van der Waals solids. Increased surface roughness was correlated to increased modulus and brittleness within films of similar composition. Decreased stiffness for soluble molecular semiconductors can be rationalized by the presence of alkyl side chains, which decrease the

  8. Line printing solution-processable small molecules with uniform surface profile via ink-jet printer.

    PubMed

    Liu, Huimin; Xu, Wei; Tan, Wanyi; Zhu, Xuhui; Wang, Jian; Peng, Junbiao; Cao, Yong

    2016-03-01

    Line printing offers a feasible approach to remove the pixel well structure which is widely used to confine the ink-jet printed solution. In the study, a uniform line is printed by an ink-jet printer. To achieve a uniform surface profile of the printed line, 10vol% low-volatile solvent DMA (3,4-Dimethylanisole) is mixed with high-volatile solvent Pxy (p-xylene) as the solvent. After a solution-processable small molecule is dissolved, the surface tension of DMA solution becomes lower than that of Pxy solution, which creates an inward Marangoni flow during the solvent evaporation. The inward Marangoni flow balances out the outward capillary flow, thereby forming a flat film surface. The line width of the printed line depends on the contact angle of the solution on the hole injection layer. PMID:26669496

  9. Hybrid solar cells with ZnO-nanorods and dry processed small molecule absorber

    NASA Astrophysics Data System (ADS)

    Riedel, W.; Wiesner, S.; Greiner, D.; Hinrichs, V.; Rusu, M.; Lux-Steiner, M. Ch.

    2014-04-01

    We demonstrate hybrid solar cells with ZnO-nanorods (ZnO-NRs) prepared by a low temperature electrochemical method and small molecule organic absorber processed by dry organic vapor phase deposition. A homogeneous coverage of ZnO-NRs by the blend absorber consisting of zinc phthalocyanine (ZnPc) as donor and of fullerene C60 as acceptor is best realized when a thin C60 layer is first inserted at the ZnO-NR/ZnPc:C60 interface. ZnO-NR/C60/ZnPc:C60/MoO3/Ag solar cell devices with efficiencies of 2.8% under an illumination of 100 mW/cm2 at 25 °C are demonstrated.

  10. Epigenetic Mechanisms Regulate MHC and Antigen Processing Molecules in Human Embryonic and Induced Pluripotent Stem Cells

    PubMed Central

    Suárez-Álvarez, Beatriz; Rodriguez, Ramón M.; Calvanese, Vincenzo; Blanco-Gelaz, Miguel A.; Suhr, Steve T.; Ortega, Francisco; Otero, Jesus; Cibelli, Jose B.; Moore, Harry; Fraga, Mario F.; López-Larrea, Carlos

    2010-01-01

    Background Human embryonic stem cells (hESCs) are an attractive resource for new therapeutic approaches that involve tissue regeneration. hESCs have exhibited low immunogenicity due to low levels of Mayor Histocompatibility Complex (MHC) class-I and absence of MHC class-II expression. Nevertheless, the mechanisms regulating MHC expression in hESCs had not been explored. Methodology/Principal Findings We analyzed the expression levels of classical and non-classical MHC class-I, MHC class-II molecules, antigen-processing machinery (APM) components and NKG2D ligands (NKG2D-L) in hESCs, induced pluripotent stem cells (iPSCs) and NTera2 (NT2) teratocarcinoma cell line. Epigenetic mechanisms involved in the regulation of these genes were investigated by bisulfite sequencing and chromatin immunoprecipitation (ChIP) assays. We showed that low levels of MHC class-I molecules were associated with absent or reduced expression of the transporter associated with antigen processing 1 (TAP-1) and tapasin (TPN) components in hESCs and iPSCs, which are involved in the transport and load of peptides. Furthermore, lack of β2-microglobulin (β2m) light chain in these cells limited the expression of MHC class I trimeric molecule on the cell surface. NKG2D ligands (MICA, MICB) were observed in all pluripotent stem cells lines. Epigenetic analysis showed that H3K9me3 repressed the TPN gene in undifferentiated cells whilst HLA-B and β2m acquired the H3K4me3 modification during the differentiation to embryoid bodies (EBs). Absence of HLA-DR and HLA-G expression was regulated by DNA methylation. Conclusions/Significance Our data provide fundamental evidence for the epigenetic control of MHC in hESCs and iPSCs. Reduced MHC class I and class II expression in hESCs and iPSCs can limit their recognition by the immune response against these cells. The knowledge of these mechanisms will further allow the development of strategies to induce tolerance and improve stem cell allograft acceptance

  11. Kinetics of the processes, plasma parameters, and output characteristics of a UV emitter operating on XeI molecules and iodine molecules and atoms

    SciTech Connect

    Shuaibov, A. K.; Grabovaya, I. A.; Minya, A. I.; Homoki, Z. T.; Kalyuzhnaya, A. G.; Shchedrin, A. I.

    2011-03-15

    A kinetic model of the processes occurring in the plasma of a high-power low-pressure gas-discharge lamp is presented, and the output characteristics of the lamp are described. The lamp is excited by a longitudinal glow discharge and emits the I{sub 2}(D Prime -A Prime ) 342-nm and XeI(B-X) 253-nm bands and the 206.2-nm spectral line of atomic iodine. When the emitter operates in a sealed-off mode on the p(He): p(Xe): p(I{sub 2}) = 400: 120: (100-200) Pa mixture, the fractions of the UV radiation power of iodine atoms, exciplex molecules of xenon iodide, and iodine molecules comprise 55, 10, and 35%, respectively. At the optimal partial pressure, the maximum total radiation power of the lamp reaches 37 W, the energy efficiency being about 15%.

  12. Desulfurization study of hydrocarbon molecules by plasma process for gasoil applications

    SciTech Connect

    Mohammedi, M.N.; Leuenberger, J.L.; Amouroux, J.

    1996-12-31

    During these last years, many investigations have been made on sulphur elimination processes from hydrocarbon feedstocks because of environmental regulations which are more and more strict. This is a study on a plasma process dedicated to heavy hydrocarbon hydrotreatment and hazardous substances removing such as sulphur compounds. It is a co-processing of a fluidized spouted bed and an inductively coupled plasma working at atmospheric pressure. A high flow of hydrogen radicals is generated and a rapid quench of the plasma leads to an increase of hydrogen radical life-time and promotes chemical reactions of desulfurization at low temperature (700-900 K). The primary objective of this work is to understand the cleavage of C-S bond under these plasma conditions. To this end, thermodynamic calculations are done and preliminary experiments are carried out with different mixtures where n-hexadecane is chosen as the model molecule in hydrocarbon hydrocracking, and sulphur compounds are added in small amounts (0-1 % S wt). Compounds such as dimethyl sulphide, 2-butanethiol, benzothiophene and thiophene are currently studied. The influence of CH{sub 3}{degrees}, H{degrees}, HS{degrees} and PhS{degrees} (C{sub 6}H{sub 5}S{degrees}) is also considered.

  13. Desulfurization study of hydrocarbon molecules by plasma process for gasoil applications

    SciTech Connect

    1996-10-01

    During these last years, many investigations have been made on sulfur elimination processes from hydrocarbons feedstocks because of environmental regulations which are more and more strict. This is a study on a plasma process dedicated to heavy hydrocarbon hydrotreatment and hazardous substances removing such as sulphur compounds. It is a co-processing of a fluidized spouted bed and an inductively coupled plasma working at atmospheric pressure. A high flow of hydrogen radicals is generated and a rapid quench of the plasma leads to an increase of hydrogen radical life-time and promotes chemical reactions of desulfurization at low temperature (700-900 K). The primary objective of this work is to understand the cleavage of C-S bond under these plasma conditions. To this end, thermodynamical calculations are done and preliminary experiments are carried out with different mixtures where n-hexadecane is chosen as the model molecule in hydrocarbon hydrocracking, and sulfur compounds are added in small amounts (0-1% s mass). Compounds such as dimethyl sulfide, 2-butanethiol, benzothiophen and thiophen are currently studied. The influence of CH3{degrees}, H{degrees}, HS{degrees} and {Phi} is also considered.

  14. Processing And Presentation of Variant Surface Glycoprotein Molecules to T Cells In African Trypanosomiasis1

    PubMed Central

    Dagenais, Taylor R.; Freeman, Bailey E.; Demick, Karen M.; Paulnock, Donna M.; Mansfield, John M.

    2009-01-01

    Th1 cell responses to the variant surface glycoprotein (VSG) of African trypanosomes play a critical role in controlling infection through the production of IFN-γ, but the role of antigen presenting cells (APCs) in the induction and regulation of T cell mediated protection is poorly understood. In this study, we have investigated the antigen presentation capabilities of dendritic cells (DCs) and macrophages (MPs) during early trypanosome infection in relatively resistant responder and susceptible non-responder mouse strains. Splenic DCs appeared to be the primary cell responsible for activating naive VSG-specific Th cell responses in resistant responder animals through the coordinated up-regulation of costimulatory molecules, secretion of IL-12, and presentation of VSG peptides to T cells in vivo. Splenic DC depletion and the down-regulation of costimulatory markers on splenic MPs were observed in susceptible animals and may be associated with the inability of these animals to elicit a significant VSG-specific T cell response. In contrast to splenic APCs, peritoneal MPs secreted NO, failed to activate naïve Th cells in vitro, and presented relatively low levels of VSG peptides to T cells in vivo. Thus, VSG-specific Th1 cell responses may be determined by tissue- and cell-specific differences in antigen presentation. Additionally, all APCs from resistant and susceptible strains displayed a reduced ability to process and present newly encountered exogenous antigen, including new VSG molecules, during high parasitemia. Thus, initial uptake of VSG (or other trypanosome factors) may interfere with antigen presentation and have dramatic consequences for subsequent T cell responses to other proteins. PMID:19675169

  15. 77 FR 25523 - Semi-Annual Workforce Management Conference

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-30

    ... Office of the Secretary Semi-Annual Workforce Management Conference AGENCY: U.S. Department of... of Transportation, Office of the Secretary, announces the second Semi-Annual Workforce Management... for addressing labor/management issues, and safety. Registration Space is limited. Registration...

  16. 6 CFR 9.51 - Semi-annual compilation.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 6 Domestic Security 1 2012-01-01 2012-01-01 false Semi-annual compilation. 9.51 Section 9.51 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY RESTRICTIONS UPON LOBBYING Agency Reports § 9.51 Semi-annual compilation. (a) The head of each agency shall collect and compile...

  17. 15 CFR 28.600 - Semi-annual compilation.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 15 Commerce and Foreign Trade 1 2012-01-01 2012-01-01 false Semi-annual compilation. 28.600... Agency Reports § 28.600 Semi-annual compilation. (a) The head of each agency shall collect and compile... committees. Such information shall not be available for public inspection. (e) The first...

  18. 43 CFR 18.600 - Semi-annual compilation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Semi-annual compilation. 18.600 Section 18... Reports § 18.600 Semi-annual compilation. (a) The head of each agency shall collect and compile the... committees. Such information shall not be available for public inspection. (e) The first...

  19. 14 CFR 1271.600 - Semi-annual compilation.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Semi-annual compilation. 1271.600 Section... LOBBYING Agency Reports § 1271.600 Semi-annual compilation. (a) The head of each agency shall collect and... committees. Such information shall not be available for public inspection. (e) The first...

  20. 45 CFR 1158.600 - Semi-annual compilation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Semi-annual compilation. 1158.600 Section 1158.600 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL FOUNDATION ON THE ARTS AND THE HUMANITIES NATIONAL ENDOWMENT FOR THE ARTS NEW RESTRICTIONS ON LOBBYING Agency Reports § 1158.600 Semi-annual compilation. (a) The head of...

  1. 31 CFR 21.600 - Semi-annual compilation.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance: Treasury 1 2011-07-01 2011-07-01 false Semi-annual compilation. 21.600... LOBBYING Agency Reports § 21.600 Semi-annual compilation. (a) The head of each agency shall collect and... committees. Such information shall not be available for public inspection. (e) The first...

  2. 43 CFR 18.600 - Semi-annual compilation.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 43 Public Lands: Interior 1 2013-10-01 2013-10-01 false Semi-annual compilation. 18.600 Section 18... Reports § 18.600 Semi-annual compilation. (a) The head of each agency shall collect and compile the... committees. Such information shall not be available for public inspection. (e) The first...

  3. 28 CFR 69.600 - Semi-annual compilation.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Semi-annual compilation. 69.600 Section... Reports § 69.600 Semi-annual compilation. (a) The head of each agency shall collect and compile the... committees. Such information shall not be available for public inspection. (e) The first...

  4. 28 CFR 69.600 - Semi-annual compilation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Semi-annual compilation. 69.600 Section... Reports § 69.600 Semi-annual compilation. (a) The head of each agency shall collect and compile the... committees. Such information shall not be available for public inspection. (e) The first...

  5. 14 CFR 1271.600 - Semi-annual compilation.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 5 2013-01-01 2013-01-01 false Semi-annual compilation. 1271.600 Section... LOBBYING Agency Reports § 1271.600 Semi-annual compilation. (a) The head of each agency shall collect and... committees. Such information shall not be available for public inspection. (e) The first...

  6. 43 CFR 18.600 - Semi-annual compilation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 1 2012-10-01 2011-10-01 true Semi-annual compilation. 18.600 Section 18... Reports § 18.600 Semi-annual compilation. (a) The head of each agency shall collect and compile the... committees. Such information shall not be available for public inspection. (e) The first...

  7. 31 CFR 21.600 - Semi-annual compilation.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 31 Money and Finance: Treasury 1 2012-07-01 2012-07-01 false Semi-annual compilation. 21.600... LOBBYING Agency Reports § 21.600 Semi-annual compilation. (a) The head of each agency shall collect and... committees. Such information shall not be available for public inspection. (e) The first...

  8. 12 CFR 411.600 - Semi-annual compilation.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 4 2011-01-01 2011-01-01 false Semi-annual compilation. 411.600 Section 411... Reports § 411.600 Semi-annual compilation. (a) The head of each agency shall collect and compile the... committees. Such information shall not be available for public inspection. (e) The first...

  9. 31 CFR 21.600 - Semi-annual compilation.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance: Treasury 1 2013-07-01 2013-07-01 false Semi-annual compilation. 21.600... LOBBYING Agency Reports § 21.600 Semi-annual compilation. (a) The head of each agency shall collect and... committees. Such information shall not be available for public inspection. (e) The first...

  10. 43 CFR 18.600 - Semi-annual compilation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 1 2011-10-01 2011-10-01 false Semi-annual compilation. 18.600 Section 18... Reports § 18.600 Semi-annual compilation. (a) The head of each agency shall collect and compile the... committees. Such information shall not be available for public inspection. (e) The first...

  11. 28 CFR 69.600 - Semi-annual compilation.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Semi-annual compilation. 69.600 Section... Reports § 69.600 Semi-annual compilation. (a) The head of each agency shall collect and compile the... committees. Such information shall not be available for public inspection. (e) The first...

  12. 31 CFR 21.600 - Semi-annual compilation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Semi-annual compilation. 21.600... LOBBYING Agency Reports § 21.600 Semi-annual compilation. (a) The head of each agency shall collect and... committees. Such information shall not be available for public inspection. (e) The first...

  13. 15 CFR 28.600 - Semi-annual compilation.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 15 Commerce and Foreign Trade 1 2011-01-01 2011-01-01 false Semi-annual compilation. 28.600... Agency Reports § 28.600 Semi-annual compilation. (a) The head of each agency shall collect and compile... committees. Such information shall not be available for public inspection. (e) The first...

  14. 15 CFR 28.600 - Semi-annual compilation.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 15 Commerce and Foreign Trade 1 2013-01-01 2013-01-01 false Semi-annual compilation. 28.600... Agency Reports § 28.600 Semi-annual compilation. (a) The head of each agency shall collect and compile... committees. Such information shall not be available for public inspection. (e) The first...

  15. 14 CFR 1271.600 - Semi-annual compilation.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Semi-annual compilation. 1271.600 Section... LOBBYING Agency Reports § 1271.600 Semi-annual compilation. (a) The head of each agency shall collect and... committees. Such information shall not be available for public inspection. (e) The first...

  16. 22 CFR 712.600 - Semi-annual compilation.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Semi-annual compilation. 712.600 Section 712.600... LOBBYING Agency Reports § 712.600 Semi-annual compilation. (a) The head of each agency shall collect and... committees. Such information shall not be available for public inspection. (e) The first...

  17. 22 CFR 712.600 - Semi-annual compilation.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Semi-annual compilation. 712.600 Section 712.600... LOBBYING Agency Reports § 712.600 Semi-annual compilation. (a) The head of each agency shall collect and... committees. Such information shall not be available for public inspection. (e) The first...

  18. 18 CFR 1315.600 - Semi-annual compilation.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Semi-annual compilation. 1315.600 Section 1315.600 Conservation of Power and Water Resources TENNESSEE VALLEY AUTHORITY NEW RESTRICTIONS ON LOBBYING Agency Reports § 1315.600 Semi-annual compilation. (a) The head of each agency shall collect and compile the...

  19. 45 CFR 604.600 - Semi-annual compilation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Semi-annual compilation. 604.600 Section 604.600 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION NEW RESTRICTIONS ON LOBBYING Agency Reports § 604.600 Semi-annual compilation. (a) The head of each agency shall collect and compile the disclosure reports...

  20. 28 CFR 69.600 - Semi-annual compilation.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Semi-annual compilation. 69.600 Section... Reports § 69.600 Semi-annual compilation. (a) The head of each agency shall collect and compile the... committees. Such information shall not be available for public inspection. (e) The first...

  1. 12 CFR 411.600 - Semi-annual compilation.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 5 2013-01-01 2013-01-01 false Semi-annual compilation. 411.600 Section 411... Reports § 411.600 Semi-annual compilation. (a) The head of each agency shall collect and compile the... committees. Such information shall not be available for public inspection. (e) The first...

  2. 14 CFR 1271.600 - Semi-annual compilation.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 5 2014-01-01 2014-01-01 false Semi-annual compilation. 1271.600 Section... LOBBYING Agency Reports § 1271.600 Semi-annual compilation. (a) The head of each agency shall collect and... committees. Such information shall not be available for public inspection. (e) The first...

  3. 31 CFR 21.600 - Semi-annual compilation.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance: Treasury 1 2014-07-01 2014-07-01 false Semi-annual compilation. 21.600... LOBBYING Agency Reports § 21.600 Semi-annual compilation. (a) The head of each agency shall collect and... committees. Such information shall not be available for public inspection. (e) The first...

  4. 15 CFR 28.600 - Semi-annual compilation.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 15 Commerce and Foreign Trade 1 2014-01-01 2014-01-01 false Semi-annual compilation. 28.600... Agency Reports § 28.600 Semi-annual compilation. (a) The head of each agency shall collect and compile... committees. Such information shall not be available for public inspection. (e) The first...

  5. 12 CFR 411.600 - Semi-annual compilation.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 5 2014-01-01 2014-01-01 false Semi-annual compilation. 411.600 Section 411... Reports § 411.600 Semi-annual compilation. (a) The head of each agency shall collect and compile the... committees. Such information shall not be available for public inspection. (e) The first...

  6. 28 CFR 69.600 - Semi-annual compilation.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Semi-annual compilation. 69.600 Section... Reports § 69.600 Semi-annual compilation. (a) The head of each agency shall collect and compile the... committees. Such information shall not be available for public inspection. (e) The first...

  7. 45 CFR 93.600 - Semi-annual compilation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Semi-annual compilation. 93.600 Section 93.600 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION NEW RESTRICTIONS ON... first semi-annual compilation shall be submitted on May 31, 1990, and shall contain a compilation of...

  8. Single-molecule assay reveals strand switching and enhanced processivity of UvrD

    NASA Astrophysics Data System (ADS)

    Dessinges, Marie-Noëlle; Lionnet, Timothée; Xi, Xu Guang; Bensimon, David; Croquette, Vincent

    2004-04-01

    DNA helicases are enzymes capable of unwinding double-stranded DNA (dsDNA) to provide the single-stranded DNA template required in many biological processes. Among these, UvrD, an essential DNA repair enzyme, has been shown to unwind dsDNA while moving 3'-5' on one strand. Here, we use a single-molecule manipulation technique to monitor real-time changes in extension of a single, stretched, nicked dsDNA substrate as it is unwound by a single enzyme. This technique offers a means for measuring the rate, lifetime, and processivity of the enzymatic complex as a function of ATP, and for estimating the helicase step size. Strikingly, we observe a feature not seen in bulk assays: unwinding is preferentially followed by a slow, enzyme-translocation-limited rezipping of the separated strands rather than by dissociation of the enzymatic complex followed by quick rehybridization of the DNA strands. We address the mechanism underlying this phenomenon and propose a fully characterized model in which UvrD switches strands and translocates backwards on the other strand, allowing the DNA to reanneal in its wake. helicase | DNA replication | DNA repair | magnetic tweezers

  9. Single-molecule assay reveals strand switching and enhanced processivity of UvrD.

    PubMed

    Dessinges, Marie-Noëlle; Lionnet, Timothée; Xi, Xu Guang; Bensimon, David; Croquette, Vincent

    2004-04-27

    DNA helicases are enzymes capable of unwinding double-stranded DNA (dsDNA) to provide the single-stranded DNA template required in many biological processes. Among these, UvrD, an essential DNA repair enzyme, has been shown to unwind dsDNA while moving 3'-5' on one strand. Here, we use a single-molecule manipulation technique to monitor real-time changes in extension of a single, stretched, nicked dsDNA substrate as it is unwound by a single enzyme. This technique offers a means for measuring the rate, lifetime, and processivity of the enzymatic complex as a function of ATP, and for estimating the helicase step size. Strikingly, we observe a feature not seen in bulk assays: unwinding is preferentially followed by a slow, enzyme-translocation-limited rezipping of the separated strands rather than by dissociation of the enzymatic complex followed by quick rehybridization of the DNA strands. We address the mechanism underlying this phenomenon and propose a fully characterized model in which UvrD switches strands and translocates backwards on the other strand, allowing the DNA to reanneal in its wake. PMID:15079074

  10. Electron-molecule chemistry and charging processes on organic ices and Titan's icy aerosol surrogates

    NASA Astrophysics Data System (ADS)

    Pirim, C.; Gann, R. D.; McLain, J. L.; Orlando, T. M.

    2015-09-01

    Electron-induced polymerization processes and charging events that can occur within Titan's atmosphere or on its surface were simulated using electron irradiation and dissociative electron attachment (DEA) studies of nitrogen-containing organic condensates. The DEA studies probe the desorption of H- from hydrogen cyanide (HCN), acetonitrile (CH3CN), and aminoacetonitrile (NH2CH2CN) ices, as well as from synthesized tholin materials condensed or deposited onto a graphite substrate maintained at low temperature (90-130 K). The peak cross sections for H- desorption during low-energy (3-15 eV) electron irradiation were measured and range from 3 × 10-21 to 2 × 10-18 cm2. Chemical and structural transformations of HCN ice upon 2 keV electron irradiation were investigated using X-ray photoelectron and Fourier-transform infrared spectroscopy techniques. The electron-beam processed materials displayed optical properties very similar to tholins produced by conventional discharge methods. Electron and negative ion trapping lead to 1011 charges cm-2 on a flat surface which, assuming a radius of 0.05 μm for Titan aerosols, is ∼628 charges/radius (in μm). The facile charge trapping indicates that electron interactions with nitriles and complex tholin-like molecules could affect the conductivity of Titan's atmosphere due to the formation of large negative ion complexes. These negatively charged complexes can also precipitate onto Titan's surface and possibly contribute to surface reactions and the formation of dunes.

  11. High-throughput platform for real-time monitoring of biological processes by multicolor single-molecule fluorescence

    PubMed Central

    Chen, Jin; Dalal, Ravindra V.; Petrov, Alexey N.; Tsai, Albert; O’Leary, Seán E.; Chapin, Karen; Cheng, Janice; Ewan, Mark; Hsiung, Pei-Lin; Lundquist, Paul; Turner, Stephen W.; Hsu, David R.; Puglisi, Joseph D.

    2014-01-01

    Zero-mode waveguides provide a powerful technology for studying single-molecule real-time dynamics of biological systems at physiological ligand concentrations. We customized a commercial zero-mode waveguide-based DNA sequencer for use as a versatile instrument for single-molecule fluorescence detection and showed that the system provides long fluorophore lifetimes with good signal to noise and low spectral cross-talk. We then used a ribosomal translation assay to show real-time fluidic delivery during data acquisition, showing it is possible to follow the conformation and composition of thousands of single biomolecules simultaneously through four spectral channels. This instrument allows high-throughput multiplexed dynamics of single-molecule biological processes over long timescales. The instrumentation presented here has broad applications to single-molecule studies of biological systems and is easily accessible to the biophysical community. PMID:24379388

  12. Roll-to-Roll Solution-Processible Small-Molecule OLEDs

    SciTech Connect

    Liu, Jie Jerry

    2012-07-31

    The objective of this program is to develop key knowledge and make critical connections between technologies needed to enable low-cost manufacturing of OLED lighting products. In particular, the program was intended to demonstrate the feasibility of making high performance Small-Molecule OLEDs (SM-OLED) using a roll-to-roll (R2R) wet-coating technique by addressing the following technical risks (1) Whether the wet-coating technique can provide high performance OLEDs, (2) Whether SM-OLED can be made in a R2R manner, (3) What are the requirements for coating equipment, and (4) Whether R2R OLEDs can have the same performance as the lab controls. The program has been managed and executed according to the Program Management Plan (PMP) that was first developed at the beginning of the program and further revised accordingly as the program progressed. Significant progress and risk reductions have been accomplished by the end of the program. Specific achievements include: (1) Demonstrated that wet-coating can provide OLEDs with high LPW and long lifetime; (2) Demonstrated R2R OLEDs can be as efficient as batch controls (Figure 1) (3) Developed & validated basic designs for key equipment necessary for R2R SM-OLEDs; (4) Developed know-hows & specifications on materials & ink formulations critical to wetcoating; (5) Developed key R2R processes for each OLED layer (6) Identified key materials and components such as flexible barrier substrates necessary for R2R OLEDs.

  13. Efficient solution-processed small molecule: Cadmium selenide quantum dot bulk heterojunction solar cells

    SciTech Connect

    Gupta, Vinay; Upreti, Tanvi; Chand, Suresh

    2013-12-16

    We report bulk heterojunction solar cells based on blends of solution-processed small molecule [7,7′-(4,4-bis(2-ethylhexyl)-4H-silolo[3,2-b:4,5-b′]dithiophene-2,6-diyl) bis(6-fluoro-4-(5′-hexyl-[2,2′-bithiophen]-5yl)benzo[c] [1,2,5] thiadiazole)] p-DTS(FBTTh{sub 2}){sub 2}: Cadmium Selenide (CdSe) (70:30, 60:40, 50:50, and 40:60) in the device configuration: Indium Tin Oxide /poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS)/p-DTS(FBTTh{sub 2}){sub 2}: CdSe/Ca/Al. The optimized ratio of p-DTS(FBTTh{sub 2}){sub 2}:CdSe::60:40 leads to a short circuit current density (J{sub sc}) = 5.45 mA/cm{sup 2}, open circuit voltage (V{sub oc}) = 0.727 V, and fill factor (FF) = 51%, and a power conversion efficiency = 2.02% at 100 mW/cm{sup 2} under AM1.5G illumination. The J{sub sc} and FF are sensitive to the ratio of p-DTS(FBTTh{sub 2}){sub 2}:CdSe, which is a crucial factor for the device performance.

  14. Ambient pollutants, polymorphisms associated with microRNA processing and adhesion molecules: the Normative Aging Study

    PubMed Central

    2011-01-01

    Background Particulate air pollution has been associated with cardiovascular morbidity and mortality, but it remains unclear which time windows and pollutant sources are most critical. MicroRNA (miRNA) is thought to be involved in cardiovascular regulation. However, little is known about whether polymorphisms in genes that process microRNAs influence response to pollutant exposure. We hypothesized that averaging times longer than routinely measured one or two day moving averages are associated with higher soluble intercellular adhesion molecule-1 (sICAM-1) and vascular cell adhesion molecule-1 (sVCAM-1) levels, and that stationary and mobile sources contribute differently to these effects. We also investigated whether single nucleotide polymorphisms (SNPs) in miRNA-processing genes modify these associations. Methods sICAM-1 and sVCAM-1 were measured from 1999-2008 and matched to air pollution monitoring for fine particulate matter (PM2.5) black carbon, and sulfates (SO42-). We selected 17 SNPs in five miRNA-processing genes. Mixed-effects models were used to assess effects of pollutants, SNPs, and interactions under recessive inheritance models using repeated measures. Results 723 participants with 1652 observations and 1-5 visits were included in our analyses for black carbon and PM2.5. Sulfate data was available for 672 participants with 1390 observations. An interquartile range change in seven day moving average of PM2.5 (4.27 μg/m3) was associated with 3.1% (95%CI: 1.6, 4.6) and 2.5% (95%CI: 0.6, 4.5) higher sICAM-1 and sVCAM-1. Interquartile range changes in sulfates (1.39 μg/m3) were associated with 1.4% higher (95%CI: 0.04, 2.7) and 1.6% (95%CI: -0.4, 3.7) higher sICAM-1 and sVCAM-1 respectively. No significant associations were observed for black carbon. In interaction models with PM2.5, both sICAM-1 and sVCAM-1 levels were lower in rs1062923 homozygous carriers. These interactions remained significant after multiple comparisons adjustment. Conclusions PM

  15. Analysis of Dissociation—Recombination Processes for the CO2 Molecule with the Spin—Orbit Coupling Taken into Account

    NASA Astrophysics Data System (ADS)

    Ibraguimova, L. B.; Minaev, B. F.

    2016-03-01

    The dissociation CO2( X 1Σ) + M → CO( X 1Σ) + O(3P) + M and recombination CO( X 1Σ) + O(3P) + M → CO2( X 1Σ) + M processes are considered with the spin—orbit coupling taken into account in the ground and several excited states of the CO2 molecule. Because of the specific features of mutual position of potential energy surfaces of the CO2 molecule in the ground and several excited states and the large values of spin—orbit interaction matrix elements, which causes the quantum nonadiabatic transition of the molecule from one state to another, these processes become effectively spin-allowed and the rate constants for the nonadiabatic reactions have large values. The proposed dissociation and recombination mechanisms include reactions involving singlet—triplet crossings.

  16. Electron ionization of open/closed chain isocarbonic molecules relevant in plasma processing: Theoretical cross sections

    SciTech Connect

    Patel, Umang R.; Joshipura, K. N.; Pandya, Siddharth H.; Kothari, Harshit N.

    2014-01-28

    In this paper, we report theoretical electron impact ionization cross sections from threshold to 2000 eV for isocarbonic open chain molecules C{sub 4}H{sub 6}, C{sub 4}H{sub 8}, C{sub 4}F{sub 6} including their isomers, and closed chain molecules c-C{sub 4}H{sub 8} and c-C{sub 4}F{sub 8}. Theoretical formalism employed presently, viz., Complex Scattering Potential-ionization contribution method has been used successfully for a variety of polyatomic molecules. The present ionization calculations are very important since results available for the studied targets are either scarce or none. Our work affords comparison of C{sub 4} containing hydrocarbon versus fluorocarbon molecules. Comparisons of the present ionization cross sections are made wherever possible, and new ionization data are also presented.

  17. Quantum Chemistry for Solvated Molecules on Graphical Processing Units Using Polarizable Continuum Models.

    PubMed

    Liu, Fang; Luehr, Nathan; Kulik, Heather J; Martínez, Todd J

    2015-07-14

    The conductor-like polarization model (C-PCM) with switching/Gaussian smooth discretization is a widely used implicit solvation model in chemical simulations. However, its application in quantum mechanical calculations of large-scale biomolecular systems can be limited by computational expense of both the gas phase electronic structure and the solvation interaction. We have previously used graphical processing units (GPUs) to accelerate the first of these steps. Here, we extend the use of GPUs to accelerate electronic structure calculations including C-PCM solvation. Implementation on the GPU leads to significant acceleration of the generation of the required integrals for C-PCM. We further propose two strategies to improve the solution of the required linear equations: a dynamic convergence threshold and a randomized block-Jacobi preconditioner. These strategies are not specific to GPUs and are expected to be beneficial for both CPU and GPU implementations. We benchmark the performance of the new implementation using over 20 small proteins in solvent environment. Using a single GPU, our method evaluates the C-PCM related integrals and their derivatives more than 10× faster than that with a conventional CPU-based implementation. Our improvements to the linear solver provide a further 3× acceleration. The overall calculations including C-PCM solvation require, typically, 20-40% more effort than that for their gas phase counterparts for a moderate basis set and molecule surface discretization level. The relative cost of the C-PCM solvation correction decreases as the basis sets and/or cavity radii increase. Therefore, description of solvation with this model should be routine. We also discuss applications to the study of the conformational landscape of an amyloid fibril. PMID:26575750

  18. Effects of the surroundings and conformerisation of n-dodecane molecules on evaporation/condensation processes

    SciTech Connect

    Gun’ko, Vladimir M.; Nasiri, Rasoul; Sazhin, Sergei S.

    2015-01-21

    The evaporation/condensation coefficient (β) and the evaporation rate (γ) for n-dodecane vs. temperature, gas pressure, gas and liquid density, and solvation effects at a droplet surface are analysed using quantum chemical density functional theory calculations of several ensembles of conformers of n-dodecane molecules in the gas phase (hybrid functional ωB97X-D with the cc-pVTZ and cc-pVDZ basis sets) and in liquid phase (solvation method: SMD/ωB97X-D). It is shown that β depends more strongly on a number of neighbouring molecules interacting with an evaporating molecule at a droplet surface (this number is estimated through changes in the surface Gibbs free energy of solvation) than on pressure in the gas phase or conformerisation and cross-conformerisation of molecules in both phases. Thus, temperature and the surrounding effects at droplet surfaces are the dominant factors affecting the values of β for n-dodecane molecules. These values are shown to be similar (at reduced temperatures T/T{sub c} < 0.8) or slightly larger (at T/T{sub c} > 0.8) than the values of β calculated by the molecular dynamics force fields (MD FF) methods. This endorses the reliability of the previously developed classical approach to estimation of β by the MD FF methods, except at temperatures close to the critical temperature.

  19. Effects of the surroundings and conformerisation of n-dodecane molecules on evaporation/condensation processes.

    PubMed

    Gun'ko, Vladimir M; Nasiri, Rasoul; Sazhin, Sergei S

    2015-01-21

    The evaporation/condensation coefficient (β) and the evaporation rate (γ) for n-dodecane vs. temperature, gas pressure, gas and liquid density, and solvation effects at a droplet surface are analysed using quantum chemical density functional theory calculations of several ensembles of conformers of n-dodecane molecules in the gas phase (hybrid functional ωB97X-D with the cc-pVTZ and cc-pVDZ basis sets) and in liquid phase (solvation method: SMD/ωB97X-D). It is shown that β depends more strongly on a number of neighbouring molecules interacting with an evaporating molecule at a droplet surface (this number is estimated through changes in the surface Gibbs free energy of solvation) than on pressure in the gas phase or conformerisation and cross-conformerisation of molecules in both phases. Thus, temperature and the surrounding effects at droplet surfaces are the dominant factors affecting the values of β for n-dodecane molecules. These values are shown to be similar (at reduced temperatures T/Tc < 0.8) or slightly larger (at T/Tc > 0.8) than the values of β calculated by the molecular dynamics force fields (MD FF) methods. This endorses the reliability of the previously developed classical approach to estimation of β by the MD FF methods, except at temperatures close to the critical temperature. PMID:25612715

  20. A small molecule enhances RNA interference and promotes microRNA processing

    PubMed Central

    Shan, Ge; Li, Yujing; Zhang, Junliang; Li, Wendi; Szulwach, Keith E; Duan, Ranhui; Faghihi, Mohammad A; Khalil, Ahmad M; Lu, Lianghua; Paroo, Zain; Chan, Anthony W S; Shi, Zhangjie; Liu, Qinghua; Wahlestedt, Claes; He, Chuan; Jin, Peng

    2010-01-01

    Small interfering RNAs (siRNAs) and microRNAs (miRNAs) are sequence-specific post-transcriptional regulators of gene expression. Although major components of the RNA interference (RNAi) pathway have been identified, regulatory mechanisms for this pathway remain largely unknown. Here we demonstrate that the RNAi pathway can be modulated intracellularly by small molecules. We have developed a cell-based assay to monitor the activity of the RNAi pathway and find that the small-molecule enoxacin (Penetrex) enhances siRNA-mediated mRNA degradation and promotes the biogenesis of endogenous miRNAs. We show that this RNAi-enhancing activity depends on the trans-activation-responsive region RNA-binding protein. Our results provide a proof-of-principle demonstration that small molecules can be used to modulate the activity of the RNAi pathway. RNAi enhancers may be useful in the development of research tools and therapeutics. PMID:18641635

  1. Toward scalable information processing with ultracold polar molecules in an electric field: A numerical investigation

    SciTech Connect

    Bomble, Laeetitia; Pellegrini, Philippe; Ghesquiere, Pierre; Desouter-Lecomte, Michele

    2010-12-15

    We numerically investigate the possibilities of driving quantum algorithms with laser pulses in a register of ultracold NaCs polar molecules in a static electric field. We focus on the possibilities of performing scalable logical operations by considering circuits that involve intermolecular gates (implemented on adjacent interacting molecules) to enable the transfer of information from one molecule to another during conditional laser-driven population inversions. We study the implementation of an arithmetic operation (the addition of 0 or 1 on a binary digit and a carry in) which requires population inversions only and the Deutsch-Jozsa algorithm which requires a control of the phases. Under typical experimental conditions, our simulations show that high-fidelity logical operations involving several qubits can be performed in a time scale of a few hundreds of microseconds, opening promising perspectives for the manipulation of a large number of qubits in these systems.

  2. Toward Quantum Processing in Molecules: A THz-Bandwidth Coherent Memory for Light

    NASA Astrophysics Data System (ADS)

    Bustard, Philip J.; Lausten, Rune; England, Duncan G.; Sussman, Benjamin J.

    2013-08-01

    The unusual features of quantum mechanics are enabling the development of technologies not possible with classical physics. These devices utilize nonclassical phenomena in the states of atoms, ions, and solid-state media as the basis for many prototypes. Here we investigate molecular states as a distinct alternative. We demonstrate a memory for light based on storing photons in the vibrations of hydrogen molecules. The THz-bandwidth molecular memory is used to store 100-fs pulses for durations up to ˜1ns, enabling ˜104 operational time bins. The results demonstrate the promise of molecules for constructing compact ultrafast quantum photonic technologies.

  3. All-optical signal processing at 10 GHz using a photonic crystal molecule

    SciTech Connect

    Combrié, Sylvain; Lehoucq, Gaëlle; Junay, Alexandra; De Rossi, Alfredo; Malaguti, Stefania; Bellanca, Gaetano; Trillo, Stefano; Ménager, Loic; Peter Reithmaier, Johann

    2013-11-04

    We report on 10 GHz operation of an all-optical gate based on an Indium Phosphide Photonic Crystal Molecule. Wavelength conversion and all-optical mixing of microwave signals are demonstrated using the 2 mW output of a mode locked diode laser. The spectral separation of the optical pump and signal is crucial in suppressing optical cross-talk.

  4. Surface-Gasification Materials Program. Semiannual progress report for the period ending March 31, 1983

    SciTech Connect

    Bradley, R.A.

    1983-05-01

    Contents of this semiannual report include the following: introduction; (1) plant materials surveillance tests (Illinois Institute of Technology); (2) slagging gasifier refractories - appliction/evaluation (Argonne National Laboratory); (3) protective clothing and claddings - application/evaluation (ANL); (4) ceramic application technology - brittle material design (LANL); (5) advanced pressure vessel materials technology (ORNL); (6) electroslag component casting (ORNL); (7) cost reduction of the electroslag casting manufacturing process (CMU); (8) materials review and component failure analysis in support of coal gasification processes and plants (ANL); (9) process plant materials review, evaluation, and support (ORNL).

  5. Vibrational relaxation in H/sub 2/ molecules by wall collisions: applications to negative ion source processes

    SciTech Connect

    Karo, A.M.; Hiskes, J.R.; Hardy, R.J.

    1984-10-01

    In the volume of a hydrogen discharge, H/sub 2/ molecules, excited to high vibrational levels (v'' > 6), are formed either by fast-electron collisions or from H/sub 2//sup +/ ions that are accelerated across the discharge-wall potential that undergo Auger neutralization prior to impact with the discharge chamber wall. We have used computer molecular dynamics to study the de-excitation and re-excitation of vibrationally-excited H/sub 2/ molecules undergoing repeated wall collisions. The initial translational energies range from thermal to 100 eV and the initial vibrational states range from v'' = 2 to v'' = 12. The average loss or gain of vibrational, rotational, translational, and total molecular energies and the survival rates of the molecules have been evaluated. At thermal energies vibrational de-excitation is the predominant process, and a consistent picture emerges of rapid energy redistribution into all the molecular degrees of freedom and a slower rate of loss of total molecular energy to the wall. At higher translational energies (1 to 100 eV) a substantial fraction of the molecules survive with large (v'' > 6) vibrational energy. This vibrational population provides a contribution to the total excited vibrational population comparable to that from the fast-electron collision process.

  6. First Semiannual Report of the National Aeronautics and Space Administration

    NASA Technical Reports Server (NTRS)

    Glennan, T. Keith

    1959-01-01

    The First Semiannual Report of the National Aeronautics and Space Administration (NASA) is submitted to Congress pursuant to section 206 (a) of the National Aeronautics and Space Act of 1958 (Public Law 85-568) to provide for research into problems of flight within and outside the Earth's atmosphere, which states: The Administration shall submit to the President for transmittal to Congress, semiannually and at such other times as it deems desirable, a report on its activities and accomplishments.

  7. 34 CFR 82.600 - Semi-annual compilation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Semi-annual compilation. 82.600 Section 82.600 Education Office of the Secretary, Department of Education NEW RESTRICTIONS ON LOBBYING Agency Reports § 82.600 Semi-annual compilation. (a) The head of each agency shall collect and compile the disclosure reports (see appendix B) and, on May 31 and...

  8. Influence of the water molecules near surface of viral protein on virus activation process

    NASA Astrophysics Data System (ADS)

    Shepelenko, S. O.; Salnikov, A. S.; Rak, S. V.; Goncharova, E. P.; Ryzhikov, A. B.

    2009-06-01

    The infection of a cell with influenza virus comprises the stages of receptor binding to the cell membrane, endocytosis of virus particle, and fusion of the virus envelope and cell endosome membrane, which is determined by the conformational changes in hemagglutinin, a virus envelope protein, caused by pH decrease within the endosome. The pH value that induces conformation rearrangements of hemagglutinin molecule considerably varies for different influenza virus strains, first and foremost, due to the differences in amino acid structure of the corresponding proteins. The main goal of this study was to construct a model making it possible to assess the critical pH value characterizing the fusogenic activity of influenza virus hemagglutinin from the data on hemagglutinin structure and experimental verification of this model. Under this model, we assume that when the electrostatic force between interacting hemagglutinin molecules in the virus envelop exceeds a certain value, the hemagglutinin HA1 subunits are arranged so that they form a cavity sufficient for penetration of water molecules. This event leads to an irreversible hydration of the inner fragments of hemagglutinin molecule in a trimer and to the completion of conformational changes. The geometry of electrostatic field in hemagglutinin trimer was calculated taking into account the polarization effects near the interface of two dielectrics, aqueous medium and protein macromolecule. The critical pH values for the conformational changes in hemagglutinin were measured by the erythrocyte hemolysis induced by influenza virus particles when decreasing pH. The critical pH value conditionally separating the pH range into the regions with and without the conformational changes was calculated for several influenza virus H1N1 and H3N2 strains based on the data on the amino acid structure of the corresponding hemagglutinin molecules. Comparison of the theoretical and experimental values of critical pH values for

  9. DNA sequences, recombinant DNA molecules and processes producing human phospholipase inhibitor polypeptides

    SciTech Connect

    Wallner, B.P.; Pepinsky, R.B.; Garwin, J.L.

    1989-11-07

    This patent describes a recombinant DNA molecule. In comprises a DNA sequence coding for a phospholopase inhibitor polypeptide and being selected from the group consisting of: the cDNA insert of ALC, DNA sequences which code on expression for a phospholopase inhibitor, and DNA sequences which are degenerate as a result of the genetic code to either of the foregoing DNA sequences and which code on expression for a phospholipase inhibitor.

  10. 31 CFR Appendix B to Part 359 - Composite Semiannual Rate Period Table

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance:Treasury 2 2013-07-01 2013-07-01 false Composite Semiannual Rate Period Table... SAVINGS BONDS, SERIES I Pt. 359, App. B Appendix B to Part 359—Composite Semiannual Rate Period Table 1. What months make up the composite semiannual rate period? You may use the following table to find...

  11. 31 CFR Appendix B to Part 359 - Composite Semiannual Rate Period Table

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 31 Money and Finance:Treasury 2 2012-07-01 2012-07-01 false Composite Semiannual Rate Period Table... SAVINGS BONDS, SERIES I Pt. 359, App. B Appendix B to Part 359—Composite Semiannual Rate Period Table 1. What months make up the composite semiannual rate period? You may use the following table to find...

  12. 31 CFR Appendix B to Part 359 - Composite Semiannual Rate Period Table

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance: Treasury 2 2014-07-01 2014-07-01 false Composite Semiannual Rate Period... SAVINGS BONDS, SERIES I Pt. 359, App. B Appendix B to Part 359—Composite Semiannual Rate Period Table 1. What months make up the composite semiannual rate period? You may use the following table to find...

  13. 25 CFR 141.24 - Attendance at semi-annual meetings.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... THE NAVAJO, HOPI AND ZUNI RESERVATIONS General Business Practices § 141.24 Attendance at semi-annual... 25 Indians 1 2010-04-01 2010-04-01 false Attendance at semi-annual meetings. 141.24 Section 141.24... attend a semi-annual public meeting of a tribal governing body to respond to customer inquiries....

  14. 31 CFR 359.11 - What is the semiannual inflation rate?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false What is the semiannual inflation rate... BONDS, SERIES I General Information § 359.11 What is the semiannual inflation rate? The index used to determine the semiannual inflation rate is the non-seasonally adjusted CPI-U (the Consumer Price Index...

  15. Nonlinear light scattering in molecules triggered by an impulsive X-ray Raman process

    PubMed Central

    Dorfman, Konstantin E.; Bennett, Kochise; Zhang, Yu; Mukamel, Shaul

    2013-01-01

    The time-and-frequency resolved nonlinear light scattering (NLS) signals from a time evolving charge distribution of valence electrons prepared by impulsive X-ray pulses are calculated using a superoperator Green's function formalism. The signal consists of a coherent ~ N2-scaling difference frequency generation and an incoherent fluorescence ~ N-scaling component where N is the number of active molecules. The former is given by the classical Larmor formula based on the time-dependent charge density. The latter requires additional information about the electronic structure and may be recast in terms of transition amplitudes representing quantum matter pathways. PMID:24465122

  16. Non-basic high-performance molecules for solution-processed organic solar cells.

    PubMed

    van der Poll, Thomas S; Love, John A; Nguyen, Thuc-Quyen; Bazan, Guillermo C

    2012-07-17

    A new small molecule, p-DTS(FBTTh(2))(2), is designed for incorporation into solution-fabricated high-efficiency organic solar cells. Of primary importance is the incorporation of electron poor heterocycles that are not prone to protonation and thereby enable the incorporation of commonly used interlayers between the organic semiconductor and the charge collecting electrodes. These features have led to the creation of p-DTS(FBTTh(2))(2)/PC(71)BM solar cells with power conversion efficiencies of up to 7%. PMID:22674636

  17. DNA sequences, recombinant DNA molecules and processes for producing bovine growth hormone-like polypeptides in high yield

    SciTech Connect

    Buell, G.N.

    1987-09-15

    This patent describes a process for increasing the yield of a bovine growth hormone-like polypeptide to at least 100 times that of a bovine growth hormone-like polypeptide encoded by a DNA sequence. The process comprises the steps of culturing a host transformed with a recombinant DNA molecule comprising DNA sequence encoding a Met ..lambda.. or ..lambda.. bovine growth hormone-like polypetide operatively linked to an expression control sequence. The ..lambda.. is an amino terminal deletion from the amino acid sequence of mature bovine growth hormone.

  18. Interstellar molecules

    NASA Astrophysics Data System (ADS)

    Smith, D.

    1987-09-01

    Some 70 different molecular species have so far been detected variously in diffuse interstellar clouds, dense interstellar clouds, and circumstellar shells. Only simple (diatomic and triatomic) species exist in diffuse clouds because of the penetration of destructive UV radiations, whereas more complex (polyatomic) molecules survive in dense clouds as a result of the shielding against this UV radiation provided by dust grains. A current list of interstellar molecules is given together with a few other molecular species that have so far been detected only in circumstellar shells. Also listed are those interstellar species that contain rare isotopes of several elements. The gas phase ion chemistry is outlined via which the observed molecules are synthesized, and the process by which enrichment of the rare isotopes occurs in some interstellar molecules is described.

  19. Biomarker Sensors and Method for Multi-Color Imaging and Processing of Single-Molecule Life Signatures

    NASA Technical Reports Server (NTRS)

    Wade, Lawrence A. (Inventor); Collier, Charles Patrick (Inventor)

    2013-01-01

    The invention is a device including array of active regions for use in reacting one or more species in at least two of the active regions in a sequential process, e.g., sequential reactions. The device has a transparent substrate member, which has a surface region and a silane material overlying the surface region. A first active region overlies a first portion of the silane material. The first region has a first dimension of less than 1 micron in size and has first molecules capable of binding to the first portion of the silane material. A second active region overlies a second portion of the silane material. The second region has a second dimension of less than 1 micron in size, second molecules capable of binding to the second portion of the active region, and a spatial distance separates the first active region and the second active region.

  20. Coulomb explosion and binary encounter processes in collisions between slow ions and small molecules of biological interest

    SciTech Connect

    Juhasz, Z.; Sulik, B.

    2008-12-08

    In this work we study the ion impact induced fragmentation of small molecules, which are relevant for radiation damage studies in biological tissues. We present double differential ion emission yields for collisions of N{sup 6+} ions with water and methane molecules at 15 and 30 keV impact energies. The angular distribution of the fragment ions shows post-collision and nucleus-nucleus binary collision effects. In the multiple capture energy range, a strong interplay is indicated between the Coulomb explosion and the binary collision mechanisms. In the energy region, where triple capture is dominant, an unexpected angular distribution was found for water fragments, which may be attributed to orientation sensitivity of some of the capture channels. Such processes are relevant for astrophysics and radiation therapy.

  1. Molecules and Mechanisms Implicated in the Peculiar Antigenic Activation Process of Human Vγ9Vδ2 T Cells

    PubMed Central

    Harly, Christelle; Peigné, Cassie-Marie; Scotet, Emmanuel

    2014-01-01

    In human beings, as well as in most non-human primates, the major peripheral γδ T cell subset, which accounts several percent of the whole lymphoid cells pool in adults, carries an heterodimeric TCR composed of Vγ9 and Vδ2 chains. Vγ9Vδ2 T cells are specifically and strongly activated by small organic pyrophosphate molecules termed phosphoantigens (phosphoAg). These low molecular weight compounds are metabolites that are produced by either microbes or endogenously, as intermediates of the mammalian mevalonate pathway, and can accumulate intracellularly during cell stress like transformation or infection. Despite the characterization of numerous natural and synthetic phosphoAg, the mechanism(s) underlying the unique and specific antigenic activation process induced by these compounds remains poorly understood. Activation is both TCR- and cell-to-cell contact-dependent, and results of previous studies have also strongly suggested a key contribution of membrane-associated molecules of primate origin expressed on target cells. The recent identification of B7-related butyrophilin (BTN) molecules CD277/BTN3A, and more precisely their BTN3A1 isoforms, as mandatory molecules in the phosphoAg-induced recognition of target cells by Vγ9Vδ2 T cells opens important opportunities for research and applications in this field. Here, we review the unusual and complex antigenic reactivity of human Vγ9Vδ2 T cells. We highlight the recent advances in our understanding of this process, and propose a model that integrates the type I glycoprotein BTN3A1 and its intracellular B30.2 domain as a physical intermediate implicated in the detection of dysregulated intracellular levels of phosphoAg and the sensing of cell stress by Vγ9Vδ2T cells. A better understanding of this mechanism will help optimize novel immunotherapeutical approaches that utilize the unique functional potential of this major γδ T cell subset. PMID:25601861

  2. Environmental restoration/waste management-applied technology semiannual report, January--June 1992. Volume 1, No. 1

    SciTech Connect

    Adamson, M.; Kline-Simon, K.

    1992-12-31

    This is the first issue from the Lawrence Livermore National Laboratory of The Environmental Restoration/Waste Management-Applied Technology (ER/WM-AT) Semiannual Report, a continuation of the Advanced Processing Technology (APT) Semiannual Report. The name change reflects the consolidation of the APT Program with the Environmental Restoration and Waste Management Program to form the Environmental Restoration/Waste Management-Applied Technology (ER/WM-AT) Program. The Livermore site mirrors, on a small scale, many of the environmental and waste management problems of the DOE Complex. The six articles in this issue cover incineration- alternative technologies, process development for waste minimization, the proposed Mixed Waste Management Facility, dynamic underground stripping, electrical resistance tomography, and Raman spectroscopy for remote characterization of underground tanks.

  3. A solar process to end anthropogenic global warming; STEP (Solar Thermal Electrochemical Photo) generation of energetic molecules

    NASA Astrophysics Data System (ADS)

    Licht, Stuart

    2010-02-01

    An alternate process to convert solar energy is derived which captures sunlight with conversion efficiency greater than that of photovoltaics. In this STEP process, rather than electrical generation, solar energy directly provides the chemical products needed by society. This original process is derived for the solar generation of energetically rich chemicals, including chlorine, metals, hydrogen and to proactively convert anthropogenic carbon dioxide generated in burning fossil fuels. The STEP process distinguishes radiation that is energy sufficient to drive photovoltaic charge transfer, and applies all excess energy to heat and decrease the energy of enodothermic electrolysis reactions. Energy sufficient, visible, sunlight drives photovoltaic charge transfer, and available heat, infrared sunlight, and excess visible sunlight, heats, and decreases the energy of, an electrolysis reaction. For example, from the STEP conversion theory, sunlight will recycle and remove carbon dioxide at 50% solar efficiency. Details at: ``STEP generation of energetic molecules,'' J. Phys. Chem., C, 113, 16283 (2009). )

  4. Site-Resolved Two-Step Relaxation Process in an Asymmetric Dy2 Single-Molecule Magnet.

    PubMed

    Zhang, Li; Jung, Julie; Zhang, Peng; Guo, Mei; Zhao, Lang; Tang, Jinkui; Le Guennic, Boris

    2016-01-22

    Elaborate chemical design is of utmost importance in order to slow down the relaxation dynamics in single-molecule magnets (SMMs) and hence improve their potential applications. Much interest was devoted to the study of distinct relaxation processes related to the different crystal fields of crystallographically independent lanthanide ions. However, the assignment of the relaxation processes to specific metal sites remains a challenging task. To address this challenge, a new asymmetric Dy2 SMM displaying a well-separated two-step relaxation process with the anisotropic centers in fine-tuned local environments was elaborately designed. For the first time a one-to-one relationship between the metal sites and the relaxation processes was evidenced. This work sheds light on complex multiple relaxation and may direct the rational design of lanthanide SMMs with enhanced magnetic properties. PMID:26670125

  5. Efficiency enhancement in solution-processed organic small molecule: Fullerene solar cells via solvent vapor annealing

    NASA Astrophysics Data System (ADS)

    Miao, Jingsheng; Chen, Hui; Liu, Feng; Zhao, Baofeng; Hu, Lingyu; He, Zhicai; Wu, Hongbin

    2015-05-01

    We report highly efficient small molecule solar cells (SMSCs) by using dichloromethane solvent vapor annealing method. The resulted devices delivered a power conversion efficiency (PCE) of 8.3%, which is among the highest in SMSCs. Comparing to the control devices, the short circuit current (Jsc), fill factor, and PCE of solvent vapor annealed devices are significantly improved. Summarizing the results of optical absorption, film morphology, and charge carrier transporting properties, we see that the enhanced structure order and reduced size of phase separation are major reasons for the improved device performances, establishing a solid structure-property relationship. The solvent vapor annealing method can thus be a useful method in device fabrication to enhance performances of SMSCs.

  6. PDMS-Glass bonding using grafted polymeric adhesive - Alternative process flow for compatibility with patterned biological molecules

    PubMed Central

    Beh, Cyrus Weijie; Zhou, Weizhuang

    2013-01-01

    We report a novel modification of silicone elastomer, polydimethylsiloxane (PDMS) with a polymer graft that allows interfacial bonding between elastomer and glass substrate to be performed without exposure of said substrate to harsh treatment conditions like oxygen plasma. Organic molecules can thus be patterned within microfluidic channels and still remain functional post-bonding. In addition, after polymer grafting the PDMS can be stored in a desiccator for at least 40 days, and activated upon exposure to acidic buffer for bonding. The bonded devices remain fully bonded in excess of 80 psi driving pressure, with no signs of compromise to the bond integrity. Finally, we demonstrate the compatibility of our method with biological molecules using a proof-of-concept DNA sensing device, in which fluorescently-labelled DNA targets are successfully captured by a patterned probe in a device sealed using our method, while the pattern on a plasma-treated device was completely destroyed. Therefore, this method provides a much-needed alternative bonding process for incorporation of biological molecules in microfluidic devices. PMID:22858861

  7. Single-molecule optical study of cholesterol-mediated dimerization process of EGFRs in different cell lines

    NASA Astrophysics Data System (ADS)

    Lin, Chien Yu; Huang, Jung Y.; Lo, Leu-Wei

    2015-03-01

    A growing body of data reveals that the membrane cholesterol molecules can alter the signaling pathways of living cells. However, the understanding about how membrane cholesterol modulates receptor proteins remains lacking. In this study we applies single-molecule optical tracking on ligand-induced dimerization process of EGFRs in the plasma membranes of several cancer and normal cell lines. We tracked individual EGFR and dual correlated receptors in the plasma membranes of live cells. We developed an energetic model based on the generalized Langevin equation and the Cahn-Hilliard equation to help extracting information from single-molecule trajectories. From the study, we discovered that ligand-bound EGFRs move from non-raft areas into lipid raft domains. This ligand-induced motion is a common behavior for all cell lines under study. By manipulating the total amount of cholesterol with methyl- β-cyclodextrin and the local concentration of cholesterol with nystatin, we found that the amount of cholesterol can affect the stability of EGFR dimers. The EGFR dimers in the plasma membrane of normal cells are more sensitive to the local concentration changes of cholesterol than EGFR dimers in the cancer cells.

  8. Synthesis of Large Molecules in Cometary Ice Analogs: Physical Properties Related to Self-Assembly Processes

    NASA Technical Reports Server (NTRS)

    Dworkin, Jason P.; Sandford, Scott A.; Deamer, David W.; Gillette, J. Seb; Zare, Richard N.; Allamandola, Louis J. (Technical Monitor)

    1999-01-01

    The combination of realistic laboratory simulations and infrared observations have revolutionized our understanding of interstellar dust and ice-the main component of comets. Since comets and carbonaceous micrometeorites may have been important sources of volatiles and carbon compounds on the early Earth, their organic composition may be related to the origin of life. Ices on grains in molecular clouds contain a variety of simple molecules. The D/H ratios of the comets Hale-Bopp and Hyakutake are consistent with a primarily interstellar ice mixture. Within the cloud and especially in the presolar nebula through the early solar system, these icy grains would have been photoprocessed by the ultraviolet producing more complex species such as hexamethylenetetramine, polyoxymethylenes, and simple keones. We reported at the 1999 Bioastronomy meeting laboratory simulations studied to identify the types of molecules which could have been generated in pre-cometary ices. Experiments were conducted by forming a realistic interstellar mixed-molecular ice (H2O, CH3OH, NH3 and CO) at approximately 10 K under high vacuum irradiated with UV light from a hydrogen plasma lamp. The gas mixture was typically 100:50:1:1, however when different ratios were used material with similar characteristics was still produced. The residue that remained after warming to room temperature was analyzed by HPLC, and by several mass spectrometric methods. This material contains a rich mixture of complex compounds with mass spectral profiles resembling those found in IDPs and meteorites. Surface tension measurements show that an amphiphilic component is also present. These species do not appear in various controls or in unphotolyzed samples. Residues from the simulations were also dispersed in aqueous media for microscopy. The organic material forms 10-40 gm diameter droplets that fluoresce at 300-450 nm under UV excitation. These droplets have a morphology and internal structure which appear

  9. Electroluminescence from Spontaneously Generated Single-Vesicle Aggregates Using Solution-Processed Small Organic Molecules.

    PubMed

    Tsai, Yu-Tang; Tseng, Kuo-Pi; Chen, Yan-Fang; Wu, Chung-Chih; Fan, Gang-Lun; Wong, Ken-Tsung; Wantz, Guillaume; Hirsch, Lionel; Raffy, Guillaume; Del Guerzo, Andre; Bassani, Dario M

    2016-01-26

    Self-assembled aggregates offer great potential for tuning the morphology of organic semiconductors, thereby controlling their size and shape. This is particularly interesting for applications in electroluminescent (EL) devices, but there has been, to date, no reports of a functional EL device in which the size and color of the emissive domains could be controlled using self-assembly. We now report a series of molecules that spontaneously self-organize into small EL domains of sub-micrometer dimensions. By tailoring the emissive chromophores in solution, spherical aggregates that have an average size of 300 nm in diameter and emit any one color, including CIE D65 white, are spontaneously formed in solution. We show that the individual aggregates can be used in EL devices built either using small patterned electrodes or using a sandwich architecture to produce devices emitting in the blue, green, red, and white. Furthermore, sequential deposition of the three primary colors yields an RGB device in which single aggregates of each color are present in close proximity. PMID:26730851

  10. Transformations of biomass-derived platform molecules: from high added-value chemicals to fuels via aqueous-phase processing.

    PubMed

    Serrano-Ruiz, Juan Carlos; Luque, Rafael; Sepúlveda-Escribano, Antonio

    2011-11-01

    Global warming issues and the medium-term depletion of fossil fuel reserves are stimulating researchers around the world to find alternative sources of energy and organic carbon. Biomass is considered by experts the only sustainable source of energy and organic carbon for our industrial society, and it has the potential to displace petroleum in the production of chemicals and liquid transportation fuels. However, the transition from a petroleum-based economy to one based on biomass requires new strategies since the petrochemical technologies, well-developed over the last century, are not valid to process the biomass-derived compounds. Unlike petroleum feedstocks, biomass derived platform molecules possess a high oxygen content that gives them low volatility, high solubility in water, high reactivity and low thermal stability, properties that favour the processing of these resources by catalytic aqueous-phase technologies at moderate temperatures. This tutorial review is aimed at providing a general overview of processes, technologies and challenges that lie ahead for a range of different aqueous-phase transformations of some of the key biomass-derived platform molecules into liquid fuels for the transportation sector and related high added value chemicals. PMID:21713268