Science.gov

Sample records for monitoring laboratory detection

  1. Laboratory Connections. Gas Monitoring Transducers.

    ERIC Educational Resources Information Center

    Powers, Michael H.

    1988-01-01

    Discusses three types of sensors; pressure, gas detection, and relative humidity. Explains their use for laboratory measurements of gas pressure and detection of specific gaseous species. Shows diagrams of devices and circuits along with examples and applications including microcomputer interfacing. (RT)

  2. Idaho National Laboratory Site Environmental Monitoring Plan

    SciTech Connect

    Joanne L. Knight

    2012-08-01

    This plan describes environmental monitoring as required by U.S. Department of Energy (DOE) Order 450.1, “Environmental Protection Program,” and additional environmental monitoring currently performed by other organizations in and around the Idaho National Laboratory (INL). The objective of DOE Order 450.1 is to implement sound stewardship practices that protect the air, water, land, and other natural and cultural resources that may be impacted by DOE operations. This plan describes the organizations responsible for conducting environmental monitoring across the INL, the rationale for monitoring, the types of media being monitored, where the monitoring is conducted, and where monitoring results can be obtained. This plan presents a summary of the overall environmental monitoring performed in and around the INL without duplicating detailed information in the various monitoring procedures and program plans currently used to conduct monitoring.

  3. Idaho National Laboratory Environmental Monitoring Plan

    SciTech Connect

    Joanne L. Knight

    2008-04-01

    This plan describes environmental monitoring as required by U.S. Department of Energy (DOE) Order 450.1, “Environmental Protection Program,” and additional environmental monitoring currently performed by other organizations in and around the Idaho National Laboratory (INL). The objective of DOE Order 450.1 is to implement sound stewardship practices that protect the air, water, land, and other natural and cultural resources that may be impacted by DOE operations. This plan describes the organizations responsible for conducting environmental monitoring across the INL, the rationale for monitoring, the types of media being monitored, where the monitoring is conducted, and where monitoring results can be obtained. This plan presents a summary of the overall environmental monitoring performed in and around the INL without duplicating detailed information in the various monitoring procedures and program plans currently used to conduct monitoring.

  4. Idaho National Laboratory Site Environmental Monitoring Plan

    SciTech Connect

    Joanne L. Knight

    2010-10-01

    This plan describes environmental monitoring as required by U.S. Department of Energy (DOE) Order 450.1, “Environmental Protection Program,” and additional environmental monitoring currently performed by other organizations in and around the Idaho National Laboratory (INL). The objective of DOE Order 450.1 is to implement sound stewardship practices that protect the air, water, land, and other natural and cultural resources that may be impacted by DOE operations. This plan describes the organizations responsible for conducting environmental monitoring across the INL, the rationale for monitoring, the types of media being monitored, where the monitoring is conducted, and where monitoring results can be obtained. This plan presents a summary of the overall environmental monitoring performed in and around the INL without duplicating detailed information in the various monitoring procedures and program plans currently used to conduct monitoring.

  5. The electrical conductivity of CO2-bearing pore waters at elevated pressure and temperature: a laboratory study and its implications in CO2 storage monitoring and leakage detection

    NASA Astrophysics Data System (ADS)

    Börner, Jana H.; Herdegen, Volker; Repke, Jens-Uwe; Spitzer, Klaus

    2015-11-01

    The electrical rock conductivity is a sensitive indicator for carbon dioxide (CO2) injection and migration processes. For a reliable balancing of the free CO2 in pore space with petrophysical models such as Archie's law or for the detection of migrating CO2, detailed knowledge of the pore water conductivity during interaction with CO2 is essential but not available yet. Contrary to common assumptions, pore water conductivity cannot be assumed constant since CO2 is a reactive gas that dissolves into the pore water in large amounts and provides additional charge carriers due to the dissociation of carbonic acid. We consequently carried out systematic laboratory experiments to quantify and analyse the changes in saline pore water conductivity caused by CO2 at thermodynamic equilibrium. Electrical conductivity is measured on pore water samples for pressures up to 30 MPa and temperatures up to 80 °C. The parameter range covers the gaseous, liquid and supercritical state of the CO2 involved. Pore water salinities from 0.006 up to 57.27 g L-1 sodium chloride were investigated as well as selective other ion species. At the same time, the CO2 concentration in the salt solution was determined by a wet-chemical procedure. A two-regime behaviour appears: for small salinities, we observe an increase of up to more than factor 3 in the electrical pore water conductivity, which strongly depends on the solution salinity (low-salinity regime). This is an expected behaviour, since the additional ions originating from the dissociation of carbonic acid positively contribute to the solution conductivity. However, when increasing salinities are considered this effect is completely diminished. For highly saline solutions, the increased mutual impeding causes the mobility of all ions to decrease, which may result in a significant reduction of conductivity by up to 15 per cent despite the added CO2 (high-salinity regime). We present the data set covering the pressure, temperature, salinity

  6. A laboratory evaluation of color video monitors

    SciTech Connect

    Terry, P.L.

    1993-07-01

    Sandia National Laboratories has considerable experience with monochrome video monitors used in alarm assessment video systems. Most of these systems, used for perimeter protection, were designed to classify rather than to identify intruders. There is a growing interest in the identification function of security video systems for both access control and insider protection. Because color video technology is rapidly changing and because color information is useful for identification purposes, Sandia National Laboratories established a program to evaluate the newest relevant color video equipment. This report documents the evaluation of an integral component, color monitors. It briefly discusses a critical parameter, dynamic range, details test procedures, and evaluates the results.

  7. Idaho National Laboratory Site Environmental Monitoring Plan

    SciTech Connect

    Jenifer Nordstrom

    2014-02-01

    This plan provides a high-level summary of environmental monitoring performed by various organizations within and around the Idaho National Laboratory (INL) Site as required by U.S. Department of Energy (DOE) Order 435.1, Radioactive Waste Management, and DOE Order 458.1, Radiation Protection of the Public and the Environment, Guide DOE/EH-0173T, Environmental Regulatory Guide for Radiological Effluent Monitoring and Environmental Surveillance, and in accordance with 40 Code of Federal Regulations (CFR) 61, National Emission Standards for Hazardous Air Pollutants. The purpose of these orders is to 1) implement sound stewardship practices that protect the air, water, land, and other natural and cultural resources that may be impacted by DOE operations, and 2) to establish standards and requirements for the operations of DOE and DOE contractors with respect to protection of the environment and members of the public against undue risk from radiation. This plan describes the organizations responsible for conducting environmental monitoring across the INL Site, the rationale for monitoring, the types of media being monitored, where the monitoring is conducted, and where monitoring results can be obtained. Detailed monitoring procedures, program plans, or other governing documents used by contractors or agencies to implement requirements are referenced in this plan. This plan covers all planned monitoring and environmental surveillance. Nonroutine activities such as special research studies and characterization of individual sites for environmental restoration are outside the scope of this plan.

  8. Laboratory detection of marijuana use.

    PubMed

    Schwartz, R H; Hawks, R L

    1985-08-01

    Frequent smoking of cannabis (marijuana) has been shown to be associated with a decline in social, mental, and perceptual skills and, during adolescence, with maladaptive emotional development. Urinalysis for the detection of such use can be a useful tool for the physician responsible for treatment and counseling of adolescents who develop habitual use of marijuana. Primary methods for urinalysis detection of cannabis use include the homogeneous enzyme immunoassay (EMIT) and the radioimmunoassay. These and other methods are discussed along with the issues of "false" results (both positive and negative) and the "limits of interpretation" that can be placed on a positive urine result. The pharmacokinetics and metabolism of the active constituents of cannabis are described as well as the interpretation of urinalysis results as they relate to use patterns. Guidelines are presented for the primary care physician for selecting candidates for such testing and for the use of such tests in the treatment or counseling of adolescents for whom marijuana abuse has become a psychological and social problem. PMID:2989570

  9. Monitoring hydraulic fracture growth: Laboratory experiments

    SciTech Connect

    Groenenboom, J.; Dam, D.B. van

    2000-04-01

    The authors carry out small-scale hydraulic fracture experiments to investigate the physics of hydraulic fracturing. The laboratory experiments are combined with time-lapse ultrasonic measurements with active sources using both compressional and shear-wave transducers. For the time-lapse measurements they focus on ultrasonic measurement changes during fracture growth. As a consequence they can detect the hydraulic fracture and characterize its shape and geometry during growth. Hence, this paper deals with fracture characterization using time-lapse acoustic data. Hydraulic fracturing is used in the oil and gas industry to stimulate reservoir production.

  10. USGS Blind Sample Project: monitoring and evaluating laboratory analytical quality

    USGS Publications Warehouse

    Ludtke, Amy S.; Woodworth, Mark T.

    1997-01-01

    The U.S. Geological Survey (USGS) collects and disseminates information about the Nation's water resources. Surface- and ground-water samples are collected and sent to USGS laboratories for chemical analyses. The laboratories identify and quantify the constituents in the water samples. Random and systematic errors occur during sample handling, chemical analysis, and data processing. Although all errors cannot be eliminated from measurements, the magnitude of their uncertainty can be estimated and tracked over time. Since 1981, the USGS has operated an independent, external, quality-assurance project called the Blind Sample Project (BSP). The purpose of the BSP is to monitor and evaluate the quality of laboratory analytical results through the use of double-blind quality-control (QC) samples. The information provided by the BSP assists the laboratories in detecting and correcting problems in the analytical procedures. The information also can aid laboratory users in estimating the extent that laboratory errors contribute to the overall errors in their environmental data.

  11. Gravitational wave detection in the laboratory.

    NASA Astrophysics Data System (ADS)

    Chen, Y. T.; Kawashima, N.; Othman, M.; Chia, S. P.; Karim, M.; Sanugi, B.; Lim, B. H.; Chong, K. K.

    1998-09-01

    After reviewing the research work of gravitational wave detection in the laboratory, particularly long base laser interferometer detectors, the authors report on the recent progress of gravitational wave detection using laser interferometer (Tianyin-100) in Malaysia. The authors also outline the brief plan for Tianyin-500 in the future as a full-scale observatory competitive to other projects such as Ligo, Geo600, etc.

  12. Annual environmental monitoring report of the Lawrence Berkeley Laboratory, 1980

    SciTech Connect

    Schleimer, G.E.

    1981-04-01

    The Environmental Monitoring Program of the Lawrence Berkeley Laboratory is described. Data on air and water sampling and continuous radiation monitoring for 1980 are presented, and general trends are discussed.

  13. Annual environmental monitoring report of the Lawrence Berkeley Laboratory, 1986

    SciTech Connect

    Schleimer, G.E.

    1987-04-01

    The Environmental Monitoring Program of the Lawrence Berkeley Laboratory is described. Data for 1986 are presented and general trends are discussed. Topics include radiation monitoring, wastewater discharge monitoring, dose distribution estimates, and ground water monitoring. 9 refs., 8 figs., 20 tabs.

  14. MOBILE LABORATORY FOR BACILLUS ANTHRACIS DETECTION

    Technology Transfer Automated Retrieval System (TEKTRAN)

    In response to a bioterrorism event in the Washington, DC area in October 2001 a mobile laboratory (ML) was set up in the city to conduct rapid molecular tests on environmental samples for the detection of Bacillus anthracis spores. The ML contained two Class I laminar flow hoods, a small autoclave,...

  15. Explosive detection program at Sandia National Laboratories

    SciTech Connect

    Conrad, F.J.

    1983-01-01

    A brief, general description of the Explosive Detection Program at Sandia National Laboratories is given. The six major topics of the program are: (1) Coated or Uncoated Metallic Preconcentrators; (2) a Derivatization Study; (3) a Portable Ion Mobility Spectrometer; (4) an Explosive Screening Portal; (5) Mass Spectrometer Development; and (6) an Explosive Vapor Generator.

  16. Environmental monitoring at Ames Laboratory: Calendar year 1979

    SciTech Connect

    Voss, M.D.

    1980-04-01

    The results and conclusions from the Ames Laboratory environmental monitoring programs for the Ames Laboratory Research Reactor (ALRR) are presented. The major areas of radiological monitoring were ALRR effluent air, environmental air, effluent water and environmental water. Analysis of air samples collected at the ALRR site showed detectable amounts of /sup 60/Co. This isotope was 1.5 x 10/sup -4/% of the concentration guide (1) and was probably due to ALRR operations. The radioisotope of significance in the ALRR stack effluent was tritium. The average yearly individual dose from /sup 3/H at the exclusion fence was estimated to 0.0038 mRem and the estimated dose to the entire population within an 80 Km (50 mile) radius of the ALRR was 6.31 man-Rem. These values are 0.00076% and 0.0063%, respectively, of the doses derived from the concentration guides. In the radioactive liquid waste released to the City of Ames sewage system from the ALRR complex, /sup 3/H was the predominant isotope. After dilution with other waste water from the ALRR complex, the potential dose was not more than 0.59% of the dose derived from the concentration guide.

  17. Structural health monitoring activities at National Laboratories

    SciTech Connect

    Farrar, C.R.; Doebling, S.W.; James, G.H.; Simmermacher, T.

    1997-09-01

    Sandia National Laboratories and Los Alamos National Laboratory have on-going programs to assess damage in structures and mechanical systems from changes in their dynamic characteristics. This paper provides a summary of how both institutes became involved with this technology, their experience in this field and the directions that their research in this area will be taking in the future.

  18. Computerized flow monitors detect small kicks

    SciTech Connect

    McCann, D.; White, D. )

    1992-02-24

    This paper reports on a smart alarm system installed on a number of offshore rigs and one land rig which can detect kicks more quickly than conventional systems. This rapid kick detection improves rig safety because the smaller the detected influx, the easier it is to control the well. The extensive computerized monitoring system helps drilling personnel detect fluid influxes and fluid losses before the changes in flow would normally be apparent.

  19. Annual environmental monitoring report of the Lawrence Berkeley Laboratory

    SciTech Connect

    Schleimer, G.E.; Pauer, R.O.

    1990-08-01

    The Lawrence Berkeley Laboratory (LBL) is a multiprogram national laboratory managed by the University of California (UC) for the US Department of Energy (DOE). LBL's major role is to conduct basic and applied science research that is appropriate for an energy research laboratory. The Environmental Monitoring Program of the Lawrence Berkeley Laboratory is described. Data for 1989 are presented, and general trends are discussed. 17 refs., 12 figs., 23 tabs.

  20. Improving the laboratory monitoring of absorbent oil

    SciTech Connect

    V.S. Shved; S.S. Sychev; I.V. Safina; S.A. Klykov

    2009-05-15

    The performance of absorbent coal tar oil is analyzed as a function of the constituent and group composition. The qualitative and quantitative composition of the oil that ensures the required absorbent properties is determined. Operative monitoring may be based on absorbent characteristics that permit regulation of the beginning and end of regeneration.

  1. Self-Monitoring Procedures: Basic Laboratory Skills, Instructional Package Worksheets.

    ERIC Educational Resources Information Center

    Engel, William T.; And Others

    This manual contains instructional worksheets for a course in basic laboratory skills. It has been designed to meet the needs of the treatment plant technician who has little or no previous laboratory experience and is required to monitor effluent discharges. The manual is prepared on a modular basis and includes basic mathematics, weighing…

  2. Pollution monitoring system. [photographic laboratory by-products

    NASA Technical Reports Server (NTRS)

    Goodding, R. A.

    1973-01-01

    An investigation was undertaken to identify those photographic laboratory by-products which can produce harmful reactions if released untreated. After identification of these by-products, specific monitoring systems for each of the offending ions were investigated and recommendations for implementation are presented. Appropriate monitoring systems are discussed.

  3. Environmental monitoring at the Lawrence Livermore Laboratory. 1979 annual report

    SciTech Connect

    Silver, W.J.; Lindeken, C.L.; White, J.H.; Buddemeir, R.W.

    1980-04-25

    Information on monitoring activities is reported in two sections for EDB/ERA/INIS. The first section covers all information reported except Appendix D, which gives details of sampling and analytical procedures for environmental monitoring used at Lawrence Livermore Laboratory. A separate abstract was prepared for Appendix D. (JGB)

  4. Optimiziing the laboratory monitoring of biological wastewater-purification systems

    SciTech Connect

    S.V. Gerasimov

    2009-05-15

    Optimization of the laboratory monitoring of biochemical wastewater-treatment systems at coke plants is considered, for the example of OAO Koks. By adopting a methodological approach to determine the necessary data from chemical analysis, it is possible to reduce the time, labor, and materials required for monitoring, without impairing the purification process or compromising the plant's environmental policies.

  5. CONTROL CONSOLE FOR MTR FISSION PRODUCT MONITOR, USED TO DETECT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    CONTROL CONSOLE FOR MTR FISSION PRODUCT MONITOR, USED TO DETECT BREAKS IN CLADDING OF FUEL ELEMENTS. COUNT-RATE METER IN TOP PANEL INDICATES AMOUNT OF RADIOACTIVITY. LOWER PANELS SUPPLY POWER AND AMPLIFICATION OF SIGNALS GENERATED BY SCINTILLATION COUNTER/PHOTOMULTIPLIER TUBE COMBINATION IN RESPONSE TO RADIOACTIVITY IN A SAMPLE OF THE COOLING WATER. INL NEGATIVE NO. 56-771. Jack L. Anderson, Photographer, 3/15/1956. - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

  6. Air Monitoring for Hazardous Gas Detection

    NASA Technical Reports Server (NTRS)

    Arkin, C. Richard; Griffin, Timothy P.; Adams, Frederick W.; Naylor, Guy; Haskell, William; Floyd, David; Curley, Charles; Follistein, Duke W.

    2004-01-01

    The Hazardous Gas Detection Lab (HGDL) at Kennedy Space Center is involved in the design and development of instrumentation that can detect and quantify various hazardous gases. Traditionally these systems are designed for leak detection of the cryogenic gases used for the propulsion of the Shuttle and other vehicles. Mass spectrometers are the basis of these systems, which provide excellent quantitation, sensitivity, selectivity, response times and detection limits. A Table lists common gases monitored for aerospace applications. The first five gases, hydrogen, helium, nitrogen, oxygen, and argon are historically the focus of the HGDL.

  7. Miniature Laboratory for Detecting Sparse Biomolecules

    NASA Technical Reports Server (NTRS)

    Lin, Ying; Yu, Nan

    2005-01-01

    A miniature laboratory system has been proposed for use in the field to detect sparsely distributed biomolecules. By emphasizing concentration and sorting of specimens prior to detection, the underlying system concept would make it possible to attain high detection sensitivities without the need to develop ever more sensitive biosensors. The original purpose of the proposal is to aid the search for signs of life on a remote planet by enabling the detection of specimens as sparse as a few molecules or microbes in a large amount of soil, dust, rocks, water/ice, or other raw sample material. Some version of the system could prove useful on Earth for remote sensing of biological contamination, including agents of biological warfare. Processing in this system would begin with dissolution of the raw sample material in a sample-separation vessel. The solution in the vessel would contain floating microscopic magnetic beads coated with substances that could engage in chemical reactions with various target functional groups that are parts of target molecules. The chemical reactions would cause the targeted molecules to be captured on the surfaces of the beads. By use of a controlled magnetic field, the beads would be concentrated in a specified location in the vessel. Once the beads were thus concentrated, the rest of the solution would be discarded. This procedure would obviate the filtration steps and thereby also eliminate the filter-clogging difficulties of typical prior sample-concentration schemes. For ferrous dust/soil samples, the dissolution would be done first in a separate vessel before the solution is transferred to the microbead-containing vessel.

  8. GPS Monitor Station Upgrade Program at the Naval Research Laboratory

    NASA Technical Reports Server (NTRS)

    Galysh, Ivan J.; Craig, Dwin M.

    1996-01-01

    One of the measurements made by the Global Positioning System (GPS) monitor stations is to measure the continuous pseudo-range of all the passing GPS satellites. The pseudo-range contains GPS and monitor station clock errors as well as GPS satellite navigation errors. Currently the time at the GPS monitor station is obtained from the GPS constellation and has an inherent inaccuracy as a result. Improved timing accuracy at the GPS monitoring stations will improve GPS performance. The US Naval Research Laboratory (NRL) is developing hardware and software for the GPS monitor station upgrade program to improve the monitor station clock accuracy. This upgrade will allow a method independent of the GPS satellite constellation of measuring and correcting monitor station time to US Naval Observatory (USNO) time. THe hardware consists of a high performance atomic cesium frequency standard (CFS) and a computer which is used to ensemble the CFS with the two CFS's currently located at the monitor station by use of a dual-mixer system. The dual-mixer system achieves phase measurements between the high-performance CFS and the existing monitor station CFS's to within 400 femtoseconds. Time transfer between USNO and a given monitor station is achieved via a two way satellite time transfer modem. The computer at the monitor station disciplines the CFS based on a comparison of one pulse per second sent from the master site at USNO. The monitor station computer is also used to perform housekeeping functions, as well as recording the health status of all three CFS's. This information is sent to the USNO through the time transfer modem. Laboratory time synchronization results in the sub nanosecond range have been observed and the ability to maintain the monitor station CFS frequency to within 3.0 x 10 (sup minus 14) of the master site at USNO.

  9. Detection of Enterovirus D68 in Canadian Laboratories

    PubMed Central

    Hatchette, Todd F.; Drews, Steven J.; Grudeski, Elsie; Booth, Tim; Martineau, Christine; Dust, Kerry; Garceau, Richard; Gubbay, Jonathan; Karnauchow, Tim; Krajden, Mel; Levett, Paul N.; Mazzulli, Tony; McDonald, Ryan R.; McNabb, Alan; Mubareka, Samira; Needle, Robert; Petrich, Astrid; Richardson, Susan; Rutherford, Candy; Smieja, Marek; Tellier, Raymond; Tipples, Graham

    2015-01-01

    The recent emergence of a severe respiratory disease caused by enterovirus D68 prompted investigation into whether Canadian hospital and provincial laboratories can detect this virus using commercial and laboratory-developed assays. This study demonstrated analytical sensitivity differences between commercial and laboratory-developed assays for the detection of enterovirus D68. PMID:25740765

  10. Alternatives for Laboratory Measurement of Aerosol Samples from the International Monitoring System of the CTBT

    NASA Astrophysics Data System (ADS)

    Miley, H.; Forrester, J. B.; Greenwood, L. R.; Keillor, M. E.; Eslinger, P. W.; Regmi, R.; Biegalski, S.; Erikson, L. E.

    2013-12-01

    The aerosol samples taken from the CTBT International Monitoring Systems stations are measured in the field with a minimum detectable concentration (MDC) of ~30 microBq/m3 of Ba-140. This is sufficient to detect far less than 1 kt of aerosol fission products in the atmosphere when the station is in the plume from such an event. Recent thinking about minimizing the potential source region (PSR) from a detection has led to a desire for a multi-station or multi-time period detection. These would be connected through the concept of ';event formation', analogous to event formation in seismic event study. However, to form such events, samples from the nearest neighbors of the detection would require re-analysis with a more sensitive laboratory to gain a substantially lower MDC, and potentially find radionuclide concentrations undetected by the station. The authors will present recent laboratory work with air filters showing various cost effective means for enhancing laboratory sensitivity.

  11. Blood glucose monitors: a laboratory and patient assessment.

    PubMed Central

    Webb, D J; Lovesay, J M; Ellis, A; Knight, A H

    1980-01-01

    The four blood glucose monitors available in the United Kingdom were compared by asking the opinions of 24 patients who used each monitor for two weeks, by correlating their blood glucose results with those obtained in the laboratory, and by having the monitors examined by an electronics engineer. Of the battery-operated monitors, patients preferred the Hypocount (15) to the Glucochek (9). The mains-operated units were less popular, with little to choose between Eyetone and Reflomat. Under field conditions the blood glucose results obtained with the Glucochek correlated poorly with the standard reference method. In contrast the Hypocount, Eyetone, and Reflomat machines produced good correlations. Poor results with the Glucochek were mainly due to faulty timing systems. The patients' preference for the Hypocount was supported by tests of performance under laboratory conditions and by the electronics engineer's report. PMID:7362972

  12. Annual environmental monitoring report of the Lawrence Berkeley Laboratory

    SciTech Connect

    Schleimer, G.E.

    1989-06-01

    The Environmental Monitoring Program of the Lawrence Berkeley Laboratory (LBL) is described. Data for 1988 are presented and general trends are discussed. In order to establish whether LBL research activities produced any impact on the population surrounding the laboratory, a program of environmental air and water sampling and continuous radiation monitoring was carried on throughout the year. For 1988, as in the previous several years, dose equivalents attributable to LBL radiological operations were a small fraction of both the relevant radiation protection guidelines (RPG) and of the natural radiation background. 16 refs., 7 figs., 21 tabs.

  13. LABORATORY DETECTION OF THIOCYANIC ACID HSCN

    SciTech Connect

    Bruenken, S.; Yu, Z.; Gottlieb, C. A.; McCarthy, M. C.; Thaddeus, P. E-mail: cgottlieb@cfa.harvard.ed E-mail: pthaddeus@cfa.harvard.ed

    2009-12-01

    The rotational spectrum of thiocyanic acid HSCN, a highly polar isomer of the well-known astronomical molecule isothiocyanic acid HNCS, has been measured in two radio bands: in the centimeter-wave band by Fourier transform microwave spectroscopy in a molecular beam, and in the millimeter-wave band by long-path absorption spectroscopy in a low-pressure glow discharge. Twelve spectroscopic constants were derived from more than 60 a-type rotational transitions between 11 and 346 GHz with J up to 30 and K{sub a} <= 6, including seven centimeter-wave transitions with resolved hyperfine structure. With these constants the rotational spectrum in the K{sub a} = 0 and K{sub a} = 1 ladders-those most likely to be observed in space-can now be calculated up to 400 GHz with formal uncertainties of less than 0.2 km s{sup -1} in equivalent radial velocity. Thiocyanic acid was recently identified in Sgr B2 by Halfen et al. following the laboratory measurements, and there is possible evidence for it in cold dark clouds, with the implication that HSCN may be detectable in many galactic sources.

  14. Laboratory monitoring of anticoagulation: where do we stand?

    PubMed

    Tripodi, Armando; van den Besselaar, Antonius

    2009-02-01

    The treatment of choice for acute venous thromboembolism is anticoagulant therapy with fast-acting drugs (unfractionated or low-molecular-weight heparin or fondaparinux) aimed at preventing thrombus extension, followed by extended prophylaxis with vitamin K antagonists aimed at preventing recurrence. Experience accumulated over the years has demonstrated that strict laboratory monitoring is required for unfractionated heparin and vitamin K antagonists, making use of these drugs problematic for patients and physicians and prompting researchers to develop new anticoagulants equally effective but without the requirement for laboratory monitoring. The results of clinical trials to date, albeit limited, suggest that these new drugs will probably keep their promise. However, the definitive answer will come subsequent to these clinical trials, when clinicians will start to use these drugs to treat patients in the real world. It is likely that some sort of laboratory monitoring will be required at least for selected categories of patients. Accordingly, clinical laboratories should still be prepared to monitor patients, although the numbers may hopefully decrease sharply in the next decade or so. PMID:19308891

  15. Real-time alpha monitoring of a radioactive liquid waste stream at Los Alamos National Laboratory

    SciTech Connect

    Johnson, J.D.; Whitley, C.R.; Rawool-Sullivan, M.

    1995-12-31

    This poster display concerns the development, installation, and testing of a real-time radioactive liquid waste monitor at Los Alamos National Laboratory (LANL). The detector system was designed for the LANL Radioactive Liquid Waste Treatment Facility so that influent to the plant could be monitored in real time. By knowing the activity of the influent, plant operators can better monitor treatment, better segregate waste (potentially), and monitor the regulatory compliance of users of the LANL Radioactive Liquid Waste Collection System. The detector system uses long-range alpha detection technology, which is a nonintrusive method of characterization that determines alpha activity on the liquid surface by measuring the ionization of ambient air. Extensive testing has been performed to ensure long-term use with a minimal amount of maintenance. The final design was a simple cost-effective alpha monitor that could be modified for monitoring influent waste streams at various points in the LANL Radioactive Liquid Waste Collection System.

  16. Test plan for demonstration of Rapid Transuranic Monitoring Laboratory

    SciTech Connect

    McIsaac, C.V.; Sill, C.W.; Gehrke, R.J.; Killian, E.W.; Watts, K.D.

    1993-06-01

    This plan describes tests to demonstrate the capability of the Rapid Transuranic Monitoring Laboratory (RTML) to monitor airborne alpha-emitting radionuclides and analyze soil, smear, and filter samples for alpha- and gamma-emitting radionuclides under field conditions. The RTML will be tested during June 1993 at a site adjacent to the Cold Test Pit at the Radioactive Waste Management Complex at the Idaho National Engineering Laboratory. Measurement systems installed in the RTML that will be demonstrated include two large-area ionization chamber alpha spectrometers, an x-ray/gamma-ray spectrometer, and four alpha continuous air monitors. Test objectives, requirements for data quality, experimental apparatus and procedures, and safety and logistics issues are described.

  17. Image detection monitoring system (IDMS) for landslide monitoring

    NASA Astrophysics Data System (ADS)

    Lollino, Giorgio; Allasia, Paolo; Baldo, Marco; Giordan, Daniele

    2010-05-01

    In the field of topographic displacement monitoring systems, the CNR IRPI of Turin has developed and patented a new instrumentation, named Image Detection For Monitoring System (IDMS). The IDMS is constituted by a digital reflex camera that, according to different needs, can be combined to a long range reflectorless laser distantiometer . The resulting assembly is automatically moved by an high accuracy sophisticated positioning mechanism managed by a low-consumption pc. The principle of operation is based on the analysis of a time series of pictures of an area that, processed using particular algorithms, allow to obtain topographic displacements. If necessary, with the long range laser integration it is also possible to get the displacement values in three-dimensions. The system, initially experimented with the use of a cam, has been improved using a reflex camera, developing a special software that allowed to improve performances and to set algorithms to seek the monitored areas. These implementations, in addition to the freedom from the needs of reflecting targets, increase the system flexibility that can operate in dynamic contexts where the phenomenon morphology can quickly change. With this characteristics , the IDMS can preserve the topographic total station accuracy, but it hasn't the necessity to use expensive reflecting targets, often characterized by the difficulty of their installation and maintenance. These characteristics make the system most flexible allowing to modify the investigated areas without particular logistic difficulties and without further costs.

  18. Detection of respiratory compromise by acoustic monitoring, capnography, and brain function monitoring during monitored anesthesia care.

    PubMed

    Tanaka, Pedro P; Tanaka, Maria; Drover, David R

    2014-12-01

    Episodes of apnea in sedated patients represent a risk of respiratory compromise. We hypothesized that acoustic monitoring would be equivalent to capnography for detection of respiratory pauses, with fewer false alarms. In addition, we hypothesized that the patient state index (PSI) would be correlated with the frequency of respiratory pauses and therefore could provide information about the risk of apnea during sedation. Patients undergoing sedation for surgical procedures were monitored for respiration rate using acoustic monitoring and capnography and for depth of sedation using the PSI. A clinician blinded to the acoustic and sedation monitor observed the capnograph and patient to assess sedation and episodes of apnea. Another clinician retrospectively reviewed the capnography and acoustic waveform and sound files to identify true positive and false positive respiratory pauses by each method (reference method). Sensitivity, specificity, and likelihood ratio for detection of respiratory pause was calculated for acoustic monitoring and capnography. The correlation of PSI with respiratory pause events was determined. For the 51 respiratory pauses validated by retrospective analysis, the sensitivity, specificity, and likelihood ratio positive for detection were 16, 96 %, and 3.5 for clinician observation; 88, 7 %, and 1.0 for capnography; and 55, 87 %, and 4.1 for acoustic monitoring. There was no correlation between PSI and respiratory pause events. Acoustic monitoring had the highest likelihood ratio positive for detection of respiratory pause events compared with capnography and clinician observation and, therefore, may provide the best method for respiration rate monitoring during these procedures. PMID:24420342

  19. 1992 Environmental monitoring report, Sandia National Laboratories, Albuquerque, New Mexico

    SciTech Connect

    Culp, T.; Cox, W.; Hwang, H.; Irwin, M.; Jones, A.; Matz, B.; Molley, K.; Rhodes, W.; Stermer, D.; Wolff, T.

    1993-09-01

    This 1992 report contains monitoring data from routine radiological and nonradiological environmental surveillance activities. summaries of significant environmental compliance programs in progress, such as National Environmental Policy Act documentation, environmental permits, envirorunental restoration, and various waste management programs for Sandia National Laboratories in Albuquerque, New Mexico, are included. The maximum offsite dose impact was calculated to be 0.0034 millirem. The total population within a 50-mile radius of Sandia National Laboratories/New Mexico received an estimated collective dose of 0.019 person-rem during 1992 from the laboratories` operations. As in the previous year, the 1992 operations at Sandia National Laboratories/New Mexico had no discernible impact on the general public or on the environment.

  20. Knolls Atomic Power Laboratory environmental monitoring report, calendar year 1999

    SciTech Connect

    2000-12-01

    The results of the effluent and environmental monitoring programs at the three Knolls Atomic Power Laboratory (KAPL) Sites are summarized and assessed in this report. Operations at the three KAPL Sites [Knolls Site, Niskayuna, New York; Kesselring Site, West Milton, New York; S1C Site, Windsor, Connecticut] during calendar year 1999 resulted in no significant release of hazardous substances or radioactivity to the environment. The effluent and environmental monitoring programs conducted by KAPL are designed to determine the effectiveness of treatment and control methods, to provide measurement of the concentrations in effluents for comparison with applicable standards, and to assess resultant concentrations in the environment. The monitoring programs include analyses of samples of liquid and gaseous effluents for chemical constituents and radioactivity as well as monitoring of environmental air, water, sediment, and fish. Radiation measurements are also made around the perimeter of each Site and at off-site background locations.

  1. Facility Effluent Monitoring Plan for the 325 Radiochemical Processing Laboratory

    SciTech Connect

    Shields, K.D.; Ballinger, M.Y.

    1999-04-02

    This Facility Effluent Monitoring Plan (FEMP) has been prepared for the 325 Building Radiochemical Processing Laboratory (RPL) at the Pacific Northwest National Laboratory (PNNL) to meet the requirements in DOE Order 5400.1, ''General Environmental Protection Programs.'' This FEMP has been prepared for the RPL primarily because it has a ''major'' (potential to emit >0.1 mrem/yr) emission point for radionuclide air emissions according to the annual National Emission Standards for Hazardous Air Pollutants (NESHAP) assessment performed. This section summarizes the airborne and liquid effluents and the inventory based NESHAP assessment for the facility. The complete monitoring plan includes characterization of effluent streams, monitoring/sampling design criteria, a description of the monitoring systems and sample analysis, and quality assurance requirements. The RPL at PNNL houses radiochemistry research, radioanalytical service, radiochemical process development, and hazardous and radioactive mixed waste treatment activities. The laboratories and specialized facilities enable work ranging from that with nonradioactive materials to work with picogram to kilogram quantities of fissionable materials and up to megacurie quantities of other radionuclides. The special facilities within the building include two shielded hot-cell areas that provide for process development or analytical chemistry work with highly radioactive materials and a waste treatment facility for processing hazardous, mixed radioactive, low-level radioactive, and transuranic wastes generated by PNNL activities.

  2. HIV Laboratory Monitoring Reliably Identifies Persons Engaged in Care

    PubMed Central

    Dean, Bonnie B.; Hart, Rachel L.D.; Buchacz, Kate; Bozzette, Samuel A.; Wood, Kathy; Brooks, John T.

    2015-01-01

    Background Attendance at biannual medical encounters has been proposed as a minimum national standard for adequate engagement in HIV care. Using data from the HIV Outpatient Study, we analyzed how well dates of HIV-related laboratory testing correlated with attendance at biannual medical encounters. Methods HIV Outpatient Study is an open prospective cohort study of HIV-infected patients receiving outpatient care in the United States. The data set included dates for laboratory measurements and medical encounters. We included patients with at least 1 HIV laboratory test (CD4 cell count or plasma HIV RNA viral load) during 2010–2011. An HIV laboratory test was defined as associated with a medical encounter if it occurred within 3 weeks of the encounter. We assessed the predictive value of HIV laboratory tests as a proxy for adequate engagement in clinical care, defined as having had ≥2 HIV laboratory tests within 1 year and performed >90 days apart. Results A total of 10,321 HIV laboratory tests were recorded from 2909 patients. Adequate engagement in clinical care based on medical encounters was 88.2% and 77.3% when based on laboratory tests. Using HIV laboratory tests to assess engagement had a sensitivity of 85.7%, specificity of 86.0%, and positive and negative predictive values of 97.9% and 44.5%, respectively. Of the 22.7% classified as not engaged in care by the proxy measure, over half (55.5%) were actually engaged. Conclusions Using laboratory monitoring reliably classified persons as engaged in care. Of the 22.7% of patients classified as not engaged in care, most were actually engaged. PMID:25383710

  3. Environmental monitoring and assessment program forest health monitoring quality assurance project plan for detection monitoring project

    SciTech Connect

    Cline, S.P.; Alexander, S.A.; Barnard, J.E.

    1995-05-01

    The Quality Assurance Project Plan (QAP) is written specifically for the Detection Minitoring project of the interagency Forest Health Monitoring (FHM) program. Sections 1 through 3 briefly explain key features of the Environmental Monitoring and Assessment Program (EMAP), the FHM program, and their interrelationship, respectively. Section 4 describes the general quality assurance (QA) requirements for the FHM Detection Monitoring project. Section 5 contains the separate QAPs for each forest condition indicator: site condition and tree growth and regeneration, tree crown condition, tree damage assessment, photosynthetically active radiation (PAR), vegetation structure, ozone bioindicator plants, and lichen communities.

  4. 40 CFR 258.54 - Detection monitoring program.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... FOR MUNICIPAL SOLID WASTE LANDFILLS Ground-Water Monitoring and Corrective Action § 258.54 Detection monitoring program. (a) Detection monitoring is required at MSWLF units at all ground-water monitoring wells... in the unit. (2) The Director of an approved State may establish an alternative list of...

  5. 40 CFR 258.54 - Detection monitoring program.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... FOR MUNICIPAL SOLID WASTE LANDFILLS Ground-Water Monitoring and Corrective Action § 258.54 Detection monitoring program. (a) Detection monitoring is required at MSWLF units at all ground-water monitoring wells... in the unit. (2) The Director of an approved State may establish an alternative list of...

  6. 40 CFR 258.54 - Detection monitoring program.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... FOR MUNICIPAL SOLID WASTE LANDFILLS Ground-Water Monitoring and Corrective Action § 258.54 Detection monitoring program. (a) Detection monitoring is required at MSWLF units at all ground-water monitoring wells... in the unit. (2) The Director of an approved State may establish an alternative list of...

  7. 40 CFR 258.54 - Detection monitoring program.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... FOR MUNICIPAL SOLID WASTE LANDFILLS Ground-Water Monitoring and Corrective Action § 258.54 Detection monitoring program. (a) Detection monitoring is required at MSWLF units at all ground-water monitoring wells... in the unit. (2) The Director of an approved State may establish an alternative list of...

  8. 40 CFR 258.54 - Detection monitoring program.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Detection monitoring program. 258.54 Section 258.54 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Ground-Water Monitoring and Corrective Action § 258.54 Detection monitoring program. (a) Detection...

  9. TEST PLAN FOR MONITORING COOLING COILS IN A LABORATORY SETTING

    SciTech Connect

    Don B. Shirey, III

    2002-04-01

    The objective of this research project is to understand and quantify the moisture removal performance of cooling coils at part-load conditions. The project will include a comprehensive literature review, detailed measurement of cooling coil performance in a laboratory facility, monitoring cooling systems at several field test sites, and development/validation of engineering models that can be used in energy calculations and building simulations. This document contains the detailed test plan for monitoring cooling coil performance in a laboratory setting. Detailed measurements will be taken on up to 10 direct expansion (DX) and chilled water cooling coils in various configurations to understand the impact of coil geometry and operating conditions on transient moisture condensation and evaporation.

  10. Air Monitoring for Hazardous Gas Detection

    NASA Technical Reports Server (NTRS)

    Arkin, C. Richard; Naylor, Guy; Haskell, William; Floyd, David; Curley, Charles; Griffin, Timothy P.; Adams, Frederick; Follistein, Duke

    2003-01-01

    The Hazardous Gas Detection Lab is involved in the design and development of instrumentation that can detect and quantify various hazardous gases. Traditionally these systems are designed for leak detection of the cryogenic gases used for the propulsion of the Shuttle and other vehicles. Mass spectrometers are the basis of these systems, which provide excellent quantitation, sensitivity, selectivity, response and limits of detection. Unfortunately, these systems are large, heavy and expensive. This feature limits the ability to perform gas analysis in certain applications. Smaller and lighter mass spectrometer systems could be used in many more applications primarily due to the portability of the system. Such applications would include air analysis in confined spaces, in-situ environmental analysis and emergency response. In general, system cost is lowered as size is reduced. With a low cost air analysis system, several systems could be utilized for monitoring large areas. These networked systems could be deployed at job-sites for worker safety, throughout a community for pollution warnings, or dispersed in a battlefield for early warning of chemical or biological threats. Presented will be information on the first prototype of this type of system. Included will be field trial data, with this prototype performing air analysis autonomously from an aircraft.

  11. An inexpensive dual-chamber particle monitor: laboratory characterization

    SciTech Connect

    Rufus Edwards; Kirk R. Smith; Brent Kirby; Tracy Allen; Charles D. Litton; Susanne Hering

    2006-06-15

    In developing countries, high levels of particle pollution from the use of coal and biomass fuels for household cooking and heating are a major cause of ill health and premature mortality. Existing monitoring equipment makes routine quantification of household particle pollution levels difficult. Recent advances have enabled the development of a small, portable, data-logging particle monitor modified from commercial smoke alarm technology that can meet the needs of surveys in the developing world at reasonable cost. Laboratory comparisons of a prototype particle monitor developed at the University of California at Berkeley (UCB) with gravimetric filters, a tapered element oscillating microbalance, and a TSI DustTrak to quantify the UCB particle monitor response as a function of both concentration and particle size and to examine sensor response in relation to changes in temperature, relative humidity, and elevation are presented. UCB particle monitors showed good linearity in response to different concentrations of laboratory-generated oleic acid aerosols with a coarse and fine size distributions. The photoelectric and ionization chamber showed a wide range of responses based on particle size and, thus, require calibration with the aerosol of interest. The ionization chamber was five times more sensitive to fine rather than coarse particles, whereas the photoelectric chamber was five times more sensitive to coarse than fine. The ratio of the response between the two sensors has the potential for mass calibration of individual data points based on estimated parameters of the size distribution. The results demonstrate the significant potential of this monitor, which will facilitate the evaluation of interventions (improved fuels, stoves, and ventilation) on indoor air pollution levels and research on the impacts of indoor particle levels on health in developing countries. 10 refs., 10 figs., 2 tabs.

  12. Pacific Northwest National Laboratory 300 area facility liquid effluent monitoring: 1994 and 1995 field tests

    SciTech Connect

    Riley, R.G.; Thompson, C.J.; Damberg, E.G.; Ballinger, M.Y.

    1997-07-01

    Pacific Northwest National Laboratory Effluent Management Services manages liquid waste streams from some of the 300 Area buildings on the Hanford Site near Richland, Washington, to ensure liquid discharges to the Columbia River are in compliance with permit requirements. The buildings are owned by the U.S. Department of Energy and operated by Pacific Northwest National Laboratory. In fiscal year (FY) 1994 and FY 1995, three field tests were conducted to gather information that could be used to (1) increase the understanding of 300 Area building liquid waste streams based on the characterization and monitoring data collected during calendar year (CY) 1994 and CY 1995 and (2) establish improved methods for evaluating facility releases. The three field tests were (1) an evaluation of a continuous monitoring/event-triggered sampling system, (2) a volatile organic compound hold-time study, and (3) an investigation of the dilution and retention properties of the 300 Area process sewer. The results from the first field test showed that future characterization and monitoring of 300 Area facility liquid waste streams could benefit significantly from augmenting continuous monitoring with event-triggered sampling. Current continuous-monitoring practices (i.e., monitoring of pH, conductivity, and flow) cannot detect discharges of organic pollutants. Effluent control effectiveness would be enhanced by incorporating a continuous total organic carbon analyzer in the system to detect events involving releases of organic compounds. In the second field test, sample hold times were shown to have a significant effect on volatile organic compound data. Samples analyzed in the field within 1 hour of collection generally had 1.5 to 3 times higher volatile organic compound concentrations than those analyzed 1.5 to 4 weeks later at on-site and off-site laboratories, respectively. The number of volatile organic compounds detected also decreased with increasing hold times.

  13. Knolls Atomic Power Laboratory environmental monitoring report, calendar year 2000

    SciTech Connect

    2001-12-01

    The results of the effluent and environmental monitoring programs at the three Knolls Atomic Power Laboratory (KAPL) Sites are summarized and assessed in this report. Operations at the Knolls Site, Niskayuna, New York and the Kesselring Site, West Milton, New York and site closure activities at the S1C Site, Windsor, Connecticut, continued to have no adverse effect on human health and the quality of the environment during calendar year 2000. The effluent and environmental monitoring programs conducted by KAPL are designed to determine the effectiveness of treatment and control methods, to provide measurement of the concentrations in effluents for comparison with applicable standards, and to assess resultant concentrations in the environment. The monitoring programs include analyses of samples of liquid and gaseous effluents for chemical constituents and radioactivity as well as monitoring of environmental air, water, sediment, and fish. Radiation measurements are also made around the perimeter of each Site and at off-site background locations. Monitoring programs at the S1C Site were reduced in scope during calendar year 2000 due to completion of site dismantlement activities during 1999.

  14. Knolls Atomic Power Laboratory environmental monitoring report, calendar year 2001

    SciTech Connect

    2002-12-31

    The results of the effluent and environmental monitoring programs at the three Knolls Atomic Power Laboratory (KAPL) Sites are summarized and assessed in this report. Operations at the Knolls and Kesselring Sites and Site closure activities at the S1C Site (also known as the KAPL Windsor Site) continue to have no adverse effect on human health and the quality of the environment. The effluent and environmental monitoring programs conducted by KAPL at the Knolls and Kesselring Sites are designed to determine the effectiveness of treatment and control methods, to provide measurement of the concentrations in effluents for comparison with applicable standards, and to assess resultant concentrations in the environment. The monitoring programs include analyses of samples of liquid and gaseous effluents for chemical constituents and radioactivity as well as environmental monitoring of air, water, sediment, and fish. Radiation measurements are also made around the perimeter of the Knolls and Kesselring Sites and at off-site background locations. The environmental monitoring program for the S1C Site continues to be reduced in scope from previous years due to the completion of Site dismantlement activities during 1999 and a return to green field conditions during 2000.

  15. Silicon Carbide Temperature Monitor Measurements at the High Temperature Test Laboratory

    SciTech Connect

    J. L. Rempe; K. G. Condie; D. L. Knudson; L. L. Snead

    2010-01-01

    Silicon carbide (SiC) temperature monitors are now available for use as temperature sensors in Advanced Test Reactor (ATR) irradiation test capsules. Melt wires or paint spots, which are typically used as temperature sensors in ATR static capsules, are limited in that they can only detect whether a single temperature is or is not exceeded. SiC monitors are advantageous because a single monitor can be used to detect for a range of temperatures that may have occurred during irradiation. As part of the efforts initiated by the ATR National Scientific User Facility (NSUF) to make SiC temperature monitors available, a capability was developed to complete post-irradiation evaluations of these monitors. As discussed in this report, the Idaho National Laboratory (INL) selected the resistance measurement approach for detecting peak irradiation temperature from SiC temperature monitors. This document describes the INL efforts to develop the capability to complete these resistance measurements. In addition, the procedure is reported that was developed to assure that high quality measurements are made in a consistent fashion.

  16. The evolution of Interior Intrusion Detection Technology at Sandia National Laboratories

    SciTech Connect

    Graham, R.H.; Workhoven, R.M.

    1987-07-01

    Interior Intrusion Detection Technology began at Sandia National Laboratories (SNL) in 1975 as part of the Fixed Facilities Physical Protection Research and Development program sponsored by the US Department of Energy in connection with their nuclear safeguards effort. This paper describes the evolution of Interior Intrusion Detection Technology at Sandia National Laboratories from the beginning of the Interior Sensor Laboratory to the present. This Laboratory was established in 1976 to evaluate commercial interior intrusion sensors and to assist in site-specific intrusion detection system designs. Examples of special test techniques and new test equipment that were developed at the Lab are presented, including the Sandia Intruder Motion Simulator (SIMS), the Sensor and Environment Monitor (SEM), and the Sandia Interior Robot (SIR). We also discuss new sensors and unique sensor combinations developed when commercial sensors were unavailable and the future application of expert systems.

  17. Laboratory detection of the elusive HSCO+ isomer.

    PubMed

    McCarthy, M C; Thaddeus, P

    2007-12-14

    The rotational spectrum of protonated carbonyl sulfide, HSCO(+), has now been detected in the centimeter-wave band in a molecular beam by Fourier transform microwave spectroscopy. Rotational and centrifugal distortion constants have been determined from transitions in the K(a)=0 ladder of the normal isotopic species, and DSCO(+) and H(34)SCO(+). HSCO(+) is systematically more abundant by a factor of three than HOCS(+), the isomer obtained by attaching the H(+) to the other end of the molecule, which ab initio calculations long predicted to be higher in energy by 4-5 kcalmol. Because HSCO(+) is comparable in polarity to HOCS(+) and is apparently more stable and because OCS is widely distributed in astronomical sources, HSCO(+) is a good candidate for detection with radio telescopes. PMID:18081381

  18. ISS Destiny Laboratory Smoke Detection Model

    NASA Technical Reports Server (NTRS)

    Brooker, John E.; Urban, David L.; Ruff, Gary A.

    2007-01-01

    Smoke transport and detection were modeled numerically in the ISS Destiny module using the NIST, Fire Dynamics Simulator code. The airflows in Destiny were modeled using the existing flow conditions and the module geometry included obstructions that simulate the currently installed hardware on orbit. The smoke source was modeled as a 0.152 by 0.152 m region that emitted smoke particulate ranging from 1.46 to 8.47 mg/s. In the module domain, the smoke source was placed in the center of each Destiny rack location and the model was run to determine the time required for the two smoke detectors to alarm. Overall the detection times were dominated by the circumferential flow, the axial flow from the intermodule ventilation and the smoke source strength.

  19. Environmental monitoring at Ames Laboratory: calendar year 1980

    SciTech Connect

    Voss, M.D.

    1981-04-01

    The results and conclusions from the Ames Laboratory environmental monitoring programs for the Ames Laboratory Research Reactor (ALRR) and other Laboratory facilities are presented. The major areas of radiological monitoring were ALRR effluent air, environmental air, effluent water and environmental water. A summary of the radioactivity found in the environment is presented. The ALRR ceased operation on December 1, 1977. Decommissioning activities began January 3, 1978, and are scheduled for completion October 1, 1981. Analysis of air samples collected at the ALRR on-site station showed no radioactivity that could be attributed to ALRR operations. The radiosotope of significance in the ALRR stack effluent was tritium (H-3). The yearly individual dose from H-3 at the exclusion fence was estimated to be 0.016 mRem and the estimated dose to the entire population within an 80 Km (50 mile) radius of the ALRR was 26.6 man-Rem. These values are 0.0032% and 0.026%, respectively, of the doses derived from the concentration guides. On September 1, 1978, the ALRR site was connected to the City of Ames sanitary sewage system. All liquids (except building foundation and roof water) from the ALRR complex are now discharged to the sewage system negating the requirement for monitoring chemical constituents of effluent and environmental waters. In the radioactive liquid waste released to the City of Ames sewage system from the ALRR complex, H-3 was the predominant isotope. After dilution with other waste water from the ALRR complex, the potential dose was not more than 0.68% of the dose derived from the concentration guide. Building foundation and roof water are discharged to a drainage gulch on site.

  20. Annual environmental monitoring report of the Lawrence Berkeley Laboratory

    SciTech Connect

    Schleimer, G.E.

    1983-04-01

    In order to establish whether LBL research activities produces any impact on the population surrounding the Laboratory, a program of environmental air and water sampling and continuous radiation monitoring was carried on throughout the year. For 1982, as in the previous several years, doses attributable to LBL radiological operations were a small fraction of the relevant radiation protection guidelines (RPG). The maximum perimeter dose equivalent was less than or equal to 24.0 mrem (the 1982 dose equivalent measured at the Building 88 monitoring station B-13A, about 5% of the RPG). The total population dose equivalent attributable to LBL operations during 1982 was less than or equal to 16 man-rem, about 0.002% of the RPG of 170 mrem/person to a suitable sample of the population.

  1. 1983 environmental monitoring report, Sandia National Laboratories, Albuquerque, New Mexico

    SciTech Connect

    Millard, G.C.; Gray, C.E.; O'Neal, B.L.

    1984-04-01

    Sandia National Laboratories (SNL) is located south of Albuquerque on Kirtland Air Force Base. Because radionuclides are potentially released from its research activities, SNL has a continuing environmental monitoring program which analyzes for cesium-137, tritium, uranium, alpha emitters, and beta emitters in water, soil, air, and vegetation. Measured radiation levels in public areas were consistent with local background in 1983. The Albuquerque population received an estimated 0.250 person-rem from airborne radioactive releases, whereas it received greater than 49,950 person-rem from naturally occurring radionuclides. 23 references, 6 figures, 15 tables.

  2. 1987 environmental monitoring report, Sandia National Laboratories, Livermore, California

    SciTech Connect

    Devlin, T.K.

    1988-04-01

    Sandia National Labortories conduct various research activities related to Department of Energy interests which have the potential for release of hazardous materials or radionuclides to the environment. A strict environmental control program places maximum emphasis on limiting releases. The environmental monitoring program conducted by Lawrence Livermore National Laboratory and augmented by Sandia is designed to measure the performance of the environmental controls. The program includes analysis of air, water, soil, vegetation, sewer effluent, ground water, and foodstuffs for various toxic, hazardous, or radioactive materials. Based on these studies, the releases of materials of concern at Sandia during 1987 were well below applicable Department of Energy standards. 8 refs., 3 figs., 12 tabs.

  3. Knolls Atomic Power Laboratory environmental monitoring report, calendar year 1996

    SciTech Connect

    1996-12-31

    The results of the effluent and environmental monitoring programs at the three Knolls Atomic Power Laboratory (KAPL) sites are summarized and assessed in this report. The principal function at KAPL sites (Knolls, Kesselring, and Windsor) is research and development in the design and operation of Naval nuclear propulsion plants. The Kesselring Site is also used for the training of personnel in the operation of these plants. The Naval nuclear propulsion plant at the Windsor Site is currently being dismantled. Operations at the three KAPL sites resulted in no significant release of hazardous substances or radioactivity to the environment. The effluent and environmental monitoring programs conducted by KAPL are designed to determine the effectiveness of treatment and control methods, to provide measurement of the concentrations in effluents for comparison with applicable standards, and to assess resultant concentrations in the environment. The monitoring programs include analyses of samples of liquid and gaseous effluents for chemical constituents and radioactivity as well as monitoring of environmental air, water, sediment, and fish. Radiation measurements are also made around the perimeter of each site and at off-site background locations.

  4. Liquid Effluent Monitoring Program at the Pacific Northwest Laboratory

    SciTech Connect

    Ballinger, M.Y.

    1995-05-01

    Pacific Northwest Laboratory (PNL) is conducting a program to monitor the waste water from PNL-operated research and development facilities on the Hanford Site. The purpose of the program is to collect data to assess administrative controls and to determine whether discharges to the process sewer meet sewer criteria. Samples have been collected on a regular basis from the major PNL facilities on the Hanford Site since March 1994. A broad range of analyses has been performed to determine the primary constituents in the liquid effluent. The sampling program is briefly summarized in the paper. Continuous monitoring of pH, conductivity, and flow also provides data on the liquid effluent streams. In addition to sampling and monitoring, the program is evaluating the dynamics of the waste stream with dye studies and is evaluating the use of newer technologies for potential deployment in future sampling/monitoring efforts. Information collected to date has been valuable in determining sources of constituents that may be higher than the Waste Acceptance Criteria (WAC) for the Treated Effluent Disposal Facility (TEDF). This facility treats the waste streams before discharge to the Columbia River.

  5. Damage detection in bridges through fiber optic structural health monitoring

    NASA Astrophysics Data System (ADS)

    Doornink, J. D.; Phares, B. M.; Wipf, T. J.; Wood, D. L.

    2006-10-01

    A fiber optic structural health monitoring (SHM) system was developed and deployed by the Iowa State University (ISU) Bridge Engineering Center (BEC) to detect gradual or sudden damage in fracture-critical bridges (FCBs). The SHM system is trained with measured performance data, which are collected by fiber optic strain sensors to identify typical bridge behavior when subjected to ambient traffic loads. Structural responses deviating from the trained behavior are considered to be signs of structural damage or degradation and are identified through analytical procedures similar to control chart analyses used in statistical process control (SPC). The demonstration FCB SHM system was installed on the US Highway 30 bridge near Ames, IA, and utilizes 40 fiber bragg grating (FBG) sensors to continuously monitor the bridge response when subjected to ambient traffic loads. After the data is collected and processed, weekly evaluation reports are developed that summarize the continuous monitoring results. Through use of the evaluation reports, the bridge owner is able to identify and estimate the location and severity of the damage. The information presented herein includes an overview of the SHM components, results from laboratory and field validation testing on the system components, and samples of the reduced and analyzed data.

  6. 1991 Environmental monitoring report Sandia National Laboratories, Albuquerque, New Mexico

    SciTech Connect

    Culp, T.; Cox, W.; Hwang, S.; Jones, A.; Longley, S.; Parsons, A.; Wolff, T.; Fish, J.; Ward, S.

    1992-11-01

    This 1991 report contains monitoring data from routine radiological and nonradiological environmental surveillance activities. Summaries of significant environmental compliance programs in progress such as National Environmental Policy Act (NEPA) documentation, environmental permits, environmental restoration (ER), and various waste management programs for Sandia National Laboratories in Albuquerque (SNL, Albuquerque) are included. The maximum offsite dose impact was calculated to be 1.3 {times} 10{sup {minus}3} mrem. The total population within a 50-mile radius of SNL, Albuquerque, received a collective dose of 0.53 person-rem during 1991 from SNL, Albuquerque, operations. As in the previous year, the 1991 operations at SNL, Albuquerque, had no discernible impact on the general public or on the environment.

  7. Environmental monitoring at Argonne National Laboratory. Annual report for 1983

    SciTech Connect

    Golchert, N.W.; Duffy, T.L.; Sedlet, J.

    1984-03-01

    The results of the environmental monitoring program at Argonne National Laboratory for 1983 are presented and discussed. To evaluate the effect of Argonne operations on the environment, measurements were made for a variety of radionuclides in air, surface water, soil, grass, bottom sediment, and milk; for a variety of chemical constituents in air, surface water, ground water, and Argonne effluent water; and of the environmental penetrating radiation dose. Sample collections and measurements were made at the site boundary and off the Argonne site for comparison purposes. Some on-site measurements were made to aid in the interpretation of the boundary and off-site data. The potential radiation dose to off-site population groups is also estimated. The results of the program are interpreted in terms of the sources and origin of the radioactive and chemical substances (natural, fallout, Argonne, and other) and are compared with applicable environmental quality standards. 19 references, 8 figures, 49 tables.

  8. Environmental monitoring at Argonne National Laboratory. Annual report for 1984

    SciTech Connect

    Golchert, N.W.; Duffy, T.L.; Sedlet, J.

    1985-03-01

    The results of the environmental monitoring program at Argonne National Laboratory for 1984 are presented and discussed. To evaluate the effect of Argonne operations on the environment, measurements were made for a variety of radionuclides in air, surface water, ground water, soil, grass, bottom sediment, and milk; for a variety of chemical constituents in surface water, ground water, and Argonne effluent water; and of the environmental penetrating radiation dose. Sample collections and measurements were made on the site, at the site boundary, and off the Argonne site for comparison purposes. The potential radiation dose to off-site population groups is also estimated. The results of the program are interpreted in terms of the sources and origin of the radioactive and chemical substances (natural, fallout, Argonne, and other) and are compared with applicable environmental quality standards. 20 refs., 8 figs., 46 tabs.

  9. Environmental monitoring at Argonne National Laboratory. Annual report for 1979

    SciTech Connect

    Golchert, N. W.; Duffy, T. L.; Sedlet, J.

    1980-03-01

    The results of the environmental monitoring program at Argonne National Laboratory for 1979 are presented and discussed. To evaluate the effect of Argonne operations on the environment, measurements were made for a variety of radionuclides in air, surface water, Argonne effluent water, soil, grass, bottom sediment, and foodstuffs; for a variety of chemical constituents in air, surface water, and Argonne effluent water; and of the environemetal penetrating radiation dose. Sample collections and measurements were made at the site boundary and off the Argonne site for comparison purposes. Some on-site measuremenets were made to aid in the interpretation of the boundary and off-site data. The results of the program are interpreted in terms of the sources and origin of the radioactive and chemical substances and are compared with applicable environmental quality standards. The potential radiation dose to off-site population groups is also estimated.

  10. Environmental monitoring at Argonne National Laboratory. Annual report, 1981

    SciTech Connect

    Golchert, N.W.; Duffy, T.L.; Sedlet, J.

    1982-03-01

    The results of the environmental monitoring program at Argonne National Laboratory for 1981 are presented and discussed. To evaluate the effect of Argonne operations on the environment, measurements were made for a variety of radionuclides in air, surface water, soil, grass, bottom sediment, and milk; for a variety of chemical constituents in air, surface water, and Argonne effluent water; and of the environmental penetrating radiation dose. Sample collections and measurements were made at the site boundary and off the Argonne site for comparison purposes. Some on-site measurements were made to aid in the interpretation of the boundary and off-site data. The results of the program are interpreted in terms of the sources and origin of the radioactive and chemical substances (natural, fallout, Argonne, and other) and are compared with applicable environmental quality standards. The potential radiation dose to off-site population groups is also estimated.

  11. Environmental monitoring at Argonne National Laboratory. Annual report for 1980

    SciTech Connect

    Golchert, N. W.; Duffy, T. L.; Sedlet, J.

    1981-03-01

    The results of the environmental monitoring program at Argonne National Laboratory for 1980 are presented and discussed. To evaluate the effect of Argonne operations on the environment, measurements were made for a variety of radionuclides in air, surface water, soil, grass, bottom sediment, and foodstuffs; for a variety of chemical constituents in air, surface water, and Argonne effluent water; and of the environmental penetrating radiation dose. Sample collections and measurements were made at the site boundary and off the Argonne site for comparison purposes. Some on-site measurements were made to aid in the interpretation of the boundary and off-site data. The results of the program are interpreted in terms of the sources and origin of the radioactive and chemical substances (natural, fallout, Argonne, and other) and are compared with applicable environmental quality standards. The potential radiation dose to off-site population groups is also estimated.

  12. Environmental monitoring at Argonne National Laboratory. Annual report for 1982

    SciTech Connect

    Golchert, N.W.; Duffy, T.L.; Sedlet, J.

    1983-03-01

    The results of the environmental monitoring program at Argonne Ntaional Laboratory for 1982 are presented and discussed. To evaluate the effect of Argonne operations on the environment, measurements were made for a variety of radionuclides in air, surface water, soil, grass, bottom sediment, and milk; for a variety of chemical constituents in air, surface water, ground water, and Argonne effluent water; and of the environmental penetrating radiation dose. Sample collections and masurements were made at the site boundary and off the Argonne site for comparison purposes. Some on-site measurements were made to aid in the interpretation of the boundary and off-site data. The results of the program are interpreted in terms of the sources and origin of the radioactive and chemical substances (natural, fallout, Argonne, and other) and are compared with applicable environmental quality standards. The potential radiation dose to off-site population groups is also estimated.

  13. 1989 Environmental monitoring report, Sandia National Laboratories, Albuquerque, New Mexico

    SciTech Connect

    Hwang, S.; Chavez, G.; Phelan, J.; Parsons, A.; Yeager, G.; Dionne, D.; Schwartz, B.; Wolff, T.; Fish, J.; Gray, C.; Thompson, D.

    1990-05-01

    This 1989 report contains monitoring data from routine radiological and nonradiological environmental surveillance activities. Summaries of significant environmental compliance programs in progress such as National Environmental Policy Act documentation, environmental permits, environmental restoration, and various waste management programs for Sandia National Laboratories in Albuquerque (SNL, Albuquerque) are included. The maximum offsite dose impact was calculated to be 8.8 {times} 10{sup {minus}4} mrem. The total Albuquerque population received a collective dose of 0.097 person-rem during 1989 from SNL, Albuquerque, operations. As in the previous year, SNL, Albuquerque, operations in 1989 had no adverse impact on the general public or on the environment. 46 refs., 20 figs., 31 tabs.

  14. 1990 Environmental Monitoring Report, Sandia National Laboratories, Albuquerque, New Mexico

    SciTech Connect

    Hwang, S.; Yeager, G.; Wolff, T.; Parsons, A.; Dionne, D.; Massey, C.; Schwartz, B.; Fish, J.; Thompson, D. ); Goodrich, M. )

    1991-05-01

    This 1990 report contains monitoring data from routine radiological and nonradiological environmental surveillance activities. Summaries of significant environmental compliance programs in progress such as National Environmental Policy Act (NEPA) documentation, environmental permits, environmental restoration, and various waste management programs for Sandia National Laboratories in Albuquerque (SNL, Albuquerque) are included. The maximum offsite dose impact was calculated to be 2.0 {times} 10{sup {minus}3} mrem. The total 50-mile population received a collective dose of 0.82 person-rem during 1990 from SNL, Albuquerque, operations. As in the previous year, the 1990 SNL operations had no adverse impact on the general public or on the environment. This report is prepared for the US Department of Energy in compliance with DOE Order 5400.1. 97 refs., 30 figs., 137 tabs.

  15. Novel Monitoring Techniques for Characterizing Frictional Interfaces in the Laboratory

    PubMed Central

    Selvadurai, Paul A.; Glaser, Steven D.

    2015-01-01

    A pressure-sensitive film was used to characterize the asperity contacts along a polymethyl methacrylate (PMMA) interface in the laboratory. The film has structural health monitoring (SHM) applications for flanges and other precision fittings and train rail condition monitoring. To calibrate the film, simple spherical indentation tests were performed and validated against a finite element model (FEM) to compare normal stress profiles. Experimental measurements of the normal stress profiles were within −7.7% to 6.6% of the numerical calculations between 12 and 50 MPa asperity normal stress. The film also possessed the capability of quantifying surface roughness, an important parameter when examining wear and attrition in SHM applications. A high definition video camera supplied data for photometric analysis (i.e., the measure of visible light) of asperities along the PMMA-PMMA interface in a direct shear configuration, taking advantage of the transparent nature of the sample material. Normal stress over individual asperities, calculated with the pressure-sensitive film, was compared to the light intensity transmitted through the interface. We found that the luminous intensity transmitted through individual asperities linearly increased 0.05643 ± 0.0012 candelas for an increase of 1 MPa in normal stress between normal stresses ranging from 23 to 33 MPa. PMID:25923930

  16. Novel monitoring techniques for characterizing frictional interfaces in the laboratory.

    PubMed

    Selvadurai, Paul A; Glaser, Steven D

    2015-01-01

    A pressure-sensitive film was used to characterize the asperity contacts along a polymethyl methacrylate (PMMA) interface in the laboratory. The film has structural health monitoring (SHM) applications for flanges and other precision fittings and train rail condition monitoring. To calibrate the film, simple spherical indentation tests were performed and validated against a finite element model (FEM) to compare normal stress profiles. Experimental measurements of the normal stress profiles were within -7.7% to 6.6% of the numerical calculations between 12 and 50 MPa asperity normal stress. The film also possessed the capability of quantifying surface roughness, an important parameter when examining wear and attrition in SHM applications. A high definition video camera supplied data for photometric analysis (i.e., the measure of visible light) of asperities along the PMMA-PMMA interface in a direct shear configuration, taking advantage of the transparent nature of the sample material. Normal stress over individual asperities, calculated with the pressure-sensitive film, was compared to the light intensity transmitted through the interface. We found that the luminous intensity transmitted through individual asperities linearly increased 0.05643 ± 0.0012 candelas for an increase of 1 MPa in normal stress between normal stresses ranging from 23 to 33 MPa. PMID:25923930

  17. Climate Monitoring and Diagnostics Laboratory No. 18. Summary report, 1989

    SciTech Connect

    Komhyr, W.D.; Rosson, R.M.

    1990-12-01

    Contents: CMDL station information; observatory reports; aerosols and radiation monitoring group; carbon cycle group; ozone group; acquisition and data management; air quality group; nitrous oxide and halocarbons group; a joint U.S./U.S.S.R. experiment for the study of desert dust and its impact on local meteorological conditions and climate; annual ozone cycle and decade trend at South Pole; wintertime black carbon aerosol measurements over the southwestern United States, December 1989; cooperative programs; precipitation chemistry; continuous aerosol monitoring with the epiphaniometer at mlo; antarctic ultraviolet spectroradiometer monitoring program; chemical resolution of fine aerosol mass at mlo: the role of organic matter; artificial windshielding of precipitation gauges in the arctic; UVB monitoring data from Rockville, Maryland; Robertson-Berger UVB meter; the CSIRO latitudinal gradient study: methane data from air samples collected at Cape Grim, Tasmania; secular variation in the carbon-13 content of atmospheric carbon dioxide; snow bunting nesting study at Barrow, Alaska; optical depth retrieval with the sunphotometer; tropospheric nitrogen oxide during spring at Barrow; chemical analyses of atmospheric particulates and gases at mlo; a temperature inversion climatology for barrow: 1976-1985; the global precipitation chemistry project; radioactivity in the surface air at brw, mlo, smo, and spo; total nitrate variations at Mauna Loa; seasonal and latitudinal trends in the (13)c/(12)c ratio of methane; aerosol constituents at American Samoa, November 1989; update on the o-ring bias; trends of the carbon isotopi composition of atmospheric methane in the southern hemisphere; bromine and surface ozone atmospheric chemistry at Barrow, Alaska, during spring 1989; USGS Barrow Observatory; radon from distant continents detected at the Mauna Loa Observatory.

  18. Development of a SNP genotyping panel for genetic monitoring of the laboratory mouse.

    PubMed

    Petkov, Petko M; Cassell, Megan A; Sargent, Evelyn E; Donnelly, Charles J; Robinson, Phil; Crew, Victor; Asquith, Steven; Haar, Raymond Vonder; Wiles, Michael V

    2004-05-01

    We have developed a genotyping system for detecting genetic contamination in the laboratory mouse based on assaying single-nucleotide polymorphism (SNP) markers positioned on all autosomes and the X chromosome. This system provides a fast, reliable, and cost-effective way for genetic monitoring, while maintaining a very high degree of confidence. We describe the allelic distribution of 235 SNPs in 48 mouse strains, thereby creating a database of polymorphisms useful for genotyping purposes. The SNP markers used in this study were chosen from publicly available SNP databases. Four genotyping methods were evaluated, and dynamic two-tube allele-specific PCR assays were developed for each marker and tested on a set of 48 inbred mouse strains. The minimal number of assays sufficient to distinguish groups consisting of different numbers of mouse strains was estimated, and a panel of 28 SNPs sufficient to distinguish virtually all of the inbred strains tested was selected. Amplifluor SNP detection assays were developed for these markers and tested on an extended list of 96 strains. This panel was used as a genetic quality control approach to monitor the genotypes of nearly 300 inbred, wild-derived, congenic, consomic, and recombinant inbred strains maintained at The Jackson Laboratory. We have concluded that this marker panel is sufficient for genetic contamination monitoring in colonies containing a large number of genetically diverse mouse strains and that reduced versions of the panel could be implemented in facilities housing a lower number of strains. PMID:15081119

  19. Integrating monitor alarms with laboratory test results to enhance patient deterioration prediction.

    PubMed

    Bai, Yong; Do, Duc H; Harris, Patricia Rae Eileen; Schindler, Daniel; Boyle, Noel G; Drew, Barbara J; Hu, Xiao

    2015-02-01

    Patient monitors in modern hospitals have become ubiquitous but they generate an excessive number of false alarms causing alarm fatigue. Our previous work showed that combinations of frequently co-occurring monitor alarms, called SuperAlarm patterns, were capable of predicting in-hospital code blue events at a lower alarm frequency. In the present study, we extend the conceptual domain of a SuperAlarm to incorporate laboratory test results along with monitor alarms so as to build an integrated data set to mine SuperAlarm patterns. We propose two approaches to integrate monitor alarms with laboratory test results and use a maximal frequent itemsets mining algorithm to find SuperAlarm patterns. Under an acceptable false positive rate FPRmax, optimal parameters including the minimum support threshold and the length of time window for the algorithm to find the combinations of monitor alarms and laboratory test results are determined based on a 10-fold cross-validation set. SuperAlarm candidates are generated under these optimal parameters. The final SuperAlarm patterns are obtained by further removing the candidates with false positive rate>FPRmax. The performance of SuperAlarm patterns are assessed using an independent test data set. First, we calculate the sensitivity with respect to prediction window and the sensitivity with respect to lead time. Second, we calculate the false SuperAlarm ratio (ratio of the hourly number of SuperAlarm triggers for control patients to that of the monitor alarms, or that of regular monitor alarms plus laboratory test results if the SuperAlarm patterns contain laboratory test results) and the work-up to detection ratio, WDR (ratio of the number of patients triggering any SuperAlarm patterns to that of code blue patients triggering any SuperAlarm patterns). The experiment results demonstrate that when varying FPRmax between 0.02 and 0.15, the SuperAlarm patterns composed of monitor alarms along with the last two laboratory test results

  20. REAL-TIME MONITORING OF A HAZARDOUS WASTE INCINERATOR WITH A MOBILE LABORATORY

    EPA Science Inventory

    The paper discusses an EPA project involving a mobile laboratory for continuous monitoring of emissions and operating parameters of hazardous waste incinerators. This Hazardous Air Pollutants Mobile Laboratory (HAPML), easily transported for use by research projects at a variety ...

  1. Environmental monitoring at the Lawrence Livermore National Laboratory: 1980 annual report

    SciTech Connect

    Toy, A.J.; Lindeken, C.L.; Griggs, K.S.; Buddemeier, R.W.

    1981-04-15

    The results of environmental monitoring for 1980 at the Livermore National Laboratory are presented. Radioactivity in air, soil, sewage, water, vegetation and food, and milk was measured. Noise pollution, beryllium, heavy metals, and pesticides were monitored. (ACR)

  2. Design of a instrumentation module for monitoring ingestive behavior in laboratory studies.

    PubMed

    Fontana, Juan M; Lopez-Meyer, Paulo; Sazonov, Edward S

    2011-01-01

    The development of accurate and objective tools for monitoring of ingestive behavior (MIB) is one of the most important needs facing studies of obesity and eating disorders. This paper presents the design of an instrumentation module for non-invasive monitoring of food ingestion in laboratory studies. The system can capture signals from a variety of sensors that characterize ingestion process (such as acoustical and other swallowing sensors, strain sensor for chewing detection and self-report buttons). In addition to the sensors, the data collection system integrates time-synchronous video footage that can be used for annotation of subject's activity. Both data and video are simultaneously and synchronously acquired and stored by a LabVIEW-based interface specifically developed for this application. This instrumentation module improves a previously developed system by eliminating the post-processing stage of data synchronization and by reducing the risks of operator's error. PMID:22254698

  3. Metallurgical Laboratory Hazardous Waste Management Facility groundwater monitoring report

    SciTech Connect

    Thompson, C.Y.

    1993-03-01

    During fourth quarter 1992, samples from 18 groundwater monitoring wells of the AMB series at the Metallurgical Laboratory Hazardous Waste Management Facility were analyzed for certain heavy metals, indicator parameters, radionuclides, volatile organic compounds, and other constituents. Six parameters exceeded final Primary Drinking Water Standards (PDWS) and the Savannah River Site Flag 2 criteria during the quarter. The results for fourth quarter 1992 are fairly consistent with the rest of the year's data. Tetrachloroethylene exceeded the final PDWS in well AMB 4D only two of the four quarters; in the other three wells in which it was elevated, it was present at similar levels throughout the year. Trichloroethylene consistently exceeded its PDWS in wells AMB 4A, 4B, 4D, 5, and 7A during the year. Trichloroethylene was elevated in well AMB 6 only during third and fourth quarters and in well AMB 7 only during fourth quarter. Total alpha-emitting radium was above the final PDWS for total radium in well AMB 5 at similar levels throughout the year and exceeded the PDWS during one of the three quarters it was analyzed for (third quarter 1992) in well AMB 10B.

  4. Laboratory evaluation of RDM-201 Respirable Dust Monitor.

    PubMed

    Samimi, B

    1986-06-01

    The current paper discusses the results of laboratory experiments conducted to evaluate the GCA Respirable Dust Monitor RDM-201 in comparison with the standard Gravimetric Respirable Dust Sampler (GRDS). The samplers were compared in parallel within the atmosphere of an inhalation chamber laden with Arizona Fine Road Dust (AFRD). A wide range of dust concentrations (i.e., from 0.17 to 32:81 mg/m3) was used in the experiments. Sampling time varied from 15 to 120 min. There was a high agreement between the two GRDSs, particularly for samples with dust weight larger than 0.5 mg. The correlation and linearity between the RDM-201 display reading and the actual weight of dust on the instrument's filter were quite high for dust samples larger than 0.5 mg, but dropped significantly for samples less than 0.5 mg. Considering the extremely high dust concentration required to collect a minimum of 0.5 mg of respirable dust within 1-min sampling time of the RDM-201's automatic sampling mode, it was concluded that the use of automatic mode intended for quick evaluation of dusty atmosphere is impractical under most ordinary dusty conditions. The RDM-201 manual mode can be used, however, as reliably as a GRDS, for extended sampling times for assessment of TWAC of respirable dust in the atmosphere of a workplace, providing that a minimum of 0.5 mg sample is collected on the filter. PMID:3739904

  5. Longitudinal Analysis of Computerized Alerts for Laboratory Monitoring of Post-liver Transplant Immunosuppressive Care

    PubMed Central

    Jacobs, Jason; Narus, Scott P.; Evans, R. Scott; Staes, Catherine J.

    2015-01-01

    Post-liver transplant patients require lifelong immunosuppressive care and monitoring. Computerized alerts can aid laboratory monitoring, but it is unknown how the distribution of alerts changes over time. We describe the changes over time of the distribution of computerized alerts for laboratory monitoring of post-liver transplant immunosuppressive care. Data were collected for post-liver transplant patients transplanted and managed at Intermountain Healthcare between 2005 and 2012. Alerts were analyzed based on year triggered, time since transplantation, hospitalization status, alert type, action taken (accepted or rejected), reason given for the action taken, and narrative comments. Alerts for overdue laboratory testing became more prevalent as time since transplantation increased. There is an increased need to support monitoring for overdue laboratory testing as the time since transplantation increases. Alerts should support providers as they monitor the evolving needs of post-transplant patients over time. We identify opportunities for improving laboratory monitoring of post-liver transplant patients. PMID:26958291

  6. Laboratory and field evaluation of a biological monitoring system using Corbicula fluminea and Mulinia lateralis

    SciTech Connect

    Waller, W.T.; Allen, H.J.; Schwalm, F.U.; Acevedo, M.F.; Ammann, L.P.; Dickson, K.L.; Kennedy, J.H.; Morgan, E.L.

    1995-12-31

    Laboratory and field experiments have been performed to evaluate a non-invasive biomonitoring system using the Asiatic clam Corbicula fluminea and Mulinia lateralis. C. fluminea was exposed to simulated episodic toxicity events in the laboratory using copper, diazinon, and regulated flow rates. Group behavior during these simulated events was compared to behavior during unstressed periods to develop a statistical model and an alarm criteria. Bayou Chico, Pensacola Bay, FL, was the site for field experiments in which M. lateralis was placed in situ to evaluate the performance of the biomonitoring system. The biomonitoring system consists of proximity sensors which detect an aluminum foil target attached to the valve of an organism. Valve movements of the clams are then digitally recorded using a personal computer. Data collected from remote sites are telemetered to the lab using short wave radio. In its final form, the authors envision an in situ biological monitoring system using bivalves deployed in aquatic systems in conjunction with automated monitoring systems like those found at USGS gauging stations. A tool such as this could be used as a warning system to increase the probability of detecting toxic events as they occur.

  7. Laboratory Detection of Respiratory Viruses by Automated Techniques

    PubMed Central

    Pérez-Ruiz, Mercedes; Pedrosa-Corral, Irene; Sanbonmatsu-Gámez, Sara; Navarro-Marí, José-María

    2012-01-01

    Advances in clinical virology for detecting respiratory viruses have been focused on nucleic acids amplification techniques, which have converted in the reference method for the diagnosis of acute respiratory infections of viral aetiology. Improvements of current commercial molecular assays to reduce hands-on-time rely on two strategies, a stepwise automation (semi-automation) and the complete automation of the whole procedure. Contributions to the former strategy have been the use of automated nucleic acids extractors, multiplex PCR, real-time PCR and/or DNA arrays for detection of amplicons. Commercial fully-automated molecular systems are now available for the detection of respiratory viruses. Some of them could convert in point-of-care methods substituting antigen tests for detection of respiratory syncytial virus and influenza A and B viruses. This article describes laboratory methods for detection of respiratory viruses. A cost-effective and rational diagnostic algorithm is proposed, considering technical aspects of the available assays, infrastructure possibilities of each laboratory and clinic-epidemiologic factors of the infection PMID:23248735

  8. Statistical Anomaly Detection for Monitoring of Human Dynamics

    NASA Astrophysics Data System (ADS)

    Kamiya, K.; Fuse, T.

    2015-05-01

    Understanding of human dynamics has drawn attention to various areas. Due to the wide spread of positioning technologies that use GPS or public Wi-Fi, location information can be obtained with high spatial-temporal resolution as well as at low cost. By collecting set of individual location information in real time, monitoring of human dynamics is recently considered possible and is expected to lead to dynamic traffic control in the future. Although this monitoring focuses on detecting anomalous states of human dynamics, anomaly detection methods are developed ad hoc and not fully systematized. This research aims to define an anomaly detection problem of the human dynamics monitoring with gridded population data and develop an anomaly detection method based on the definition. According to the result of a review we have comprehensively conducted, we discussed the characteristics of the anomaly detection of human dynamics monitoring and categorized our problem to a semi-supervised anomaly detection problem that detects contextual anomalies behind time-series data. We developed an anomaly detection method based on a sticky HDP-HMM, which is able to estimate the number of hidden states according to input data. Results of the experiment with synthetic data showed that our proposed method has good fundamental performance with respect to the detection rate. Through the experiment with real gridded population data, an anomaly was detected when and where an actual social event had occurred.

  9. Summary of gas release events detected by hydrogen monitoring

    SciTech Connect

    MCCAIN, D.J.

    1999-05-18

    This paper summarizes the results of monitoring tank headspace for flammable gas release events. In over 40 tank years of monitoring the largest detected release in a single-shell tank is 2.4 cubic meters of Hydrogen. In the double-shell tanks the largest release is 19.3 cubic meters except in SY-101 pre mixer pump installation condition.

  10. Resistance to antiplatelet drugs: molecular mechanisms and laboratory detection.

    PubMed

    Cattaneo, M

    2007-07-01

    The definition 'resistance to antiplatelet drugs' should be limited to situations in which failure of the drug to hit its pharmacological target has been documented by specific laboratory tests. Aspirin resistance, as determined by specific tests (e.g. serum thromboxane B(2)), appears to be rare (1-2%) and, in most instances, is caused by poor compliance. In contrast to aspirin, studies that used specific tests to measure the pharmacological effect of thienopyridines [e.g. vasodilator-stimulated phosphoprotein (VASP)] showed a wide variability of responses to these drugs, with significant proportions of subjects (15-30%) who are very poor responders. Inter-individual differences in the extent of metabolism of thienopyridines to their active metabolites is the most plausible mechanism for the observed inter-individual variability in platelet inhibition. The demonstration that some patients may be 'resistant' or 'poor responders' to the pharmacological effect of antiplatelet drugs, has prompted the need of laboratory monitoring of antiplatelet therapy. However, many published studies have been performed using unspecific tests of platelet function, which identify patients on antiplatelet treatment with high residual platelet reactivity, which is not necessarily because of resistance to antiplatelet drugs. Despite this drawback, identification of patients with high residual platelet reactivity may be useful to predict their risk of atherothrombotic events. However, many studies still need to be carried out to identify the ideal laboratory test and to answer basic questions on its clinical utility and cost-effectiveness, before monitoring antiplatelet therapy can be recommended in the clinical practise. Until then, monitoring of antiplatelet therapy should be considered for investigational purposes only. PMID:17635731

  11. Monitoring Sensitive Bat Species at Los Alamos National Laboratory

    SciTech Connect

    Schoenberg, Kari M.

    2014-01-15

    Bats play a critical role in ecosystems and are vulnerable to disturbance and disruption by human activities. In recent decades, bat populations in the United States and elsewhere have decreased tremendously. There are 47 different species of bat in the United States and 28 of these occur in New Mexico with 15 different species documented at the Los Alamos National Laboratory (LANL) and surrounding areas. Euderma maculatum(the spotted bat) is listed as “threatened” by the state of New Mexico and is known to occur at LANL. Four other species of bats are listed as “sensitive” and also occur here. In 1995, a four year study was initiated at LANL to assess the status of bat species of concern, elucidate distribution and relative abundance, and obtain information on roosting sites. There have been no definitive studies since then. Biologists in the Environmental Protection Division at LANL initiated a multi-year monitoring program for bats in May 2013 to implement the Biological Resources Management Plan. The objective of this ongoing study is to monitor bat species diversity and seasonal activity over time at LANL. Bat species diversity and seasonal activity were measured using an acoustic bat detector, the Pettersson D500X. This ultrasound recording unit is intended for long-term, unattended recording of bat and other high frequency animal calls. During 2013, the detector was deployed at two locations around LANL. Study sites were selected based on proximity to water where bats may be foraging. Recorded bat calls were analyzed using Sonobat, software that can help determine specific species of bat through their calls. A list of bat species at the two sites was developed and compared to lists from previous studies. Species diversity and seasonal activity, measured as the number of call sequences recorded each month, were compared between sites and among months. A total of 17,923 bat calls were recorded representing 15 species. Results indicate that there is a

  12. [Laboratory methods for detection and identification of biological pathogens].

    PubMed

    Bar-Haim, Erez; Aran, Adi; Marcus, Nir; Finkelstein, Arseny; Amsalem, Yoram; Yehezkeli, Yoav

    2005-05-01

    Laboratory detection and recognition methods of infectious diseases agents have developed markedly in recent years, following the proliferation of nucleic acid and immuno-based detection technologies. The present review summarizes the state of the art in current biorecognition methods: antigenic identification, genetic identification such as PCR, RFLP and FISH, protemics and mass spectrometry. For each method we have specified the technology and qualification required, time to result, specifity and sensitivity, while emphasizing the advantages and disadvantages of using each method for the detection of a given pathogen. Nucleic acid-based detection is more specific and sensitive than immunological-based detection, while the latter is simpler and expected to further development with the improvements in the affinity, specifity and mass production of new immunoglobulins. Protein-based detection methods have an advantage comparing to nucleic acid identification: the presence of the protein approves that the tested gene is functional. Mass spectrometry enables simultaneous detections of multiple proteins and thus holds a promise for new technical developments with a vast array of applications. Most physicians do not practice biodetection technologies in their every day routine, but encounter those terms in their clinical and academic work. The review aims to display basic information in this field in order to enable a common language with basic science specialists. PMID:15931898

  13. Development Of An Electronic Nose For Environmental Monitoring: Detection Of Specific Environmentally Important Gases At Their Odor Detection Threshold Concentration

    NASA Astrophysics Data System (ADS)

    Dentoni, Licinia; Capelli, Laura; Sironi, Selena; Del Rosso, Renato; Centola, Paolo; Della Torre, Matteo; Demattè, Fabrizio

    2011-09-01

    The use of a sensor array is demonstrated to be an effective approach to evaluate hazardous odor (or gas) emissions from industrial sites1. Therefore the possibility to use electronic noses for the prolonged survey of odor emissions from industrial sites is of particular interest for environmental monitoring purposes2. At the Olfactometric Laboratory of the Politecnico di Milano, in collaboration with Sacmi Group, Imola, an innovative electronic nose for the continuous monitoring of environmental odors is being developed. The aim of this work is to show the laboratory tests conducted to evaluate the capability of the electronic nose to recognize some specific environmentally important gases at their odor detection threshold concentration. The laboratory studies up to now focused on ammonia and butyric acid, those being compounds that can typically be found in the emissions from waste treatment plants, that may cause health effects when they exceed a given concentration level. The laboratory tests proved the sensors to be sensitive towards the considered compounds and the system to be capable of discriminating between odorous or non-odorous air, with a detection limit comparable with the detection limit of human nose.

  14. Microbiological monitoring of laboratory mice and biocontainment in individually ventilated cages: a field study.

    PubMed

    Brielmeier, M; Mahabir, E; Needham, J R; Lengger, C; Wilhelm, P; Schmidt, J

    2006-07-01

    Over recent years, the use of individually ventilated cage (IVC) rack systems in laboratory rodent facilities has increased. Since every cage in an IVC rack may be assumed to be a separate microbiological unit, comprehensive microbiological monitoring of animals kept in IVCs has become a challenging task, which may be addressed by the appropriate use of sentinel mice. Traditionally, these sentinels have been exposed to soiled bedding but more recently, the concept of exposure to exhaust air has been considered. The work reported here was aimed firstly at testing the efficiency of a sentinel-based microbiological monitoring programme under field conditions in a quarantine unit and in a multi-user unit with frequent imports of mouse colonies from various sources. Secondly, it was aimed at determining biocontainment of naturally infected mice kept in an IVC rack, which included breeding of the mice. Sentinels were exposed both to soiled bedding and to exhaust air. The mice which were used in the study carried prevalent infectious agents encountered in research animal facilities including mouse hepatitis virus (MHV), mouse parvovirus (MPV), intestinal flagellates and pinworms. Our data indicate that the sentinel-based health monitoring programme allowed rapid detection of MHV, intestinal flagellates and pinworms investigated by a combination of soiled bedding and exhaust air exposure. MHV was also detected by exposure to exhaust air only. The IVC rack used in this study provided biocontainment when infected mice were kept together with non-infected mice in separate cages in the same IVC rack. PMID:16803642

  15. Brookhaven National Laboratory environmental monitoring plan for Calendar Year 1996

    SciTech Connect

    Naidu, J.R.; Paquette, D.; Lee, R.

    1996-10-01

    As required by DOE Order 5400.1, each U.S. Department of Energy (DOE) site, facility, or activity that uses, generates, releases, or manages significant quantities of hazardous materials shall provide a written Environmental Monitoring Plan (EMP) covering effluent monitoring and environmental surveillance. DOE/EH-0173T, Environmental Regulatory Guide for Radiological Effluent Monitoring and Environmental Surveillance, provides specific guidance regarding environmental monitoring activities.

  16. Water Quality & Pollutant Source Monitoring: Field and Laboratory Procedures. Training Manual.

    ERIC Educational Resources Information Center

    Office of Water Program Operations (EPA), Cincinnati, OH. National Training and Operational Technology Center.

    This training manual presents material on techniques and instrumentation used to develop data in field monitoring programs and related laboratory operations concerned with water quality and pollution monitoring. Topics include: collection and handling of samples; bacteriological, biological, and chemical field and laboratory methods; field…

  17. Groundwater monitoring in 1988 at three Oak Ridge National Laboratory inactive waste impoundments

    SciTech Connect

    Solomon, D.K.; Wickliff, D.S.; Sealand, O.M.; Francis, C.W.

    1989-03-01

    Three unlined impoundments were formerly used to collect and, in some instances, treat wastewater generated at Oak Ridge National Laboratory (ORNL). They are (1) the 3513 Waste Holding Basin, (2) the Old Hydrofracture Facility (OHF) impoundment, and (3) the Homogeneous Reactor Experiment No. 2 (HRE) impoundment. To determine if the migration of contaminants from these impoundments presents a threat to groundwater quality, at least one upgradient groundwater monitoring well and three downgradient monitoring wells were installed in 1985. Groundwater monitoring during 1986 and 1987 revealed that the principal contaminants found in groundwater downgradient from the impoundments were radionuclides, namely /sup 90/Sr and tritium. Previous groundwater monitoring was focused largely on analyses of groundwater for toxic metals (Ag, As, Ba, Cd, Cr, Hg, Pb, Se), other constituents contained in EPA's primary drinking water standards, and radionuclides. Other than the analyses for total organic carbon and total organic halides, little attention was given to the detection of hazardous organic compounds in groundwater. The major objective in the 1988 sampling at these impoundments was to determine if hazardous organic compounds, namely volatile and semivolatile organics, are leaching into groundwater from these impoundments.

  18. TEMPERATURE MONITORING OPTIONS AVAILABLE AT THE IDAHO NATIONAL LABORATORY ADVANCED TEST REACTOR

    SciTech Connect

    J.E. Daw; J.L. Rempe; D.L. Knudson; T. Unruh; B.M. Chase; K.L Davis

    2012-03-01

    As part of the Advanced Test Reactor National Scientific User Facility (ATR NSUF) program, the Idaho National Laboratory (INL) has developed in-house capabilities to fabricate, test, and qualify new and enhanced sensors for irradiation testing. To meet recent customer requests, an array of temperature monitoring options is now available to ATR users. The method selected is determined by test requirements and budget. Melt wires are the simplest and least expensive option for monitoring temperature. INL has recently verified the melting temperature of a collection of materials with melt temperatures ranging from 100 to 1000 C with a differential scanning calorimeter installed at INL’s High Temperature Test Laboratory (HTTL). INL encapsulates these melt wires in quartz or metal tubes. In the case of quartz tubes, multiple wires can be encapsulated in a single 1.6 mm diameter tube. The second option available to ATR users is a silicon carbide temperature monitor. The benefit of this option is that a single small monitor (typically 1 mm x 1 mm x 10 mm or 1 mm diameter x 10 mm length) can be used to detect peak irradiation temperatures ranging from 200 to 800 C. Equipment has been installed at INL’s HTTL to complete post-irradiation resistivity measurements on SiC monitors, a technique that has been found to yield the most accurate temperatures from these monitors. For instrumented tests, thermocouples may be used. In addition to Type-K and Type-N thermocouples, a High Temperature Irradiation Resistant ThermoCouple (HTIR-TC) was developed at the HTTL that contains commercially-available doped molybdenum paired with a niobium alloy thermoelements. Long duration high temperature tests, in furnaces and in the ATR and other MTRs, demonstrate that the HTIR-TC is accurate up to 1800 C and insensitive to thermal neutron interactions. Thus, degradation observed at temperatures above 1100 C with Type K and N thermocouples and decalibration due to transmutation with tungsten

  19. Laboratory and astronomical detection of the deuterated ethynyl radical CCD

    NASA Technical Reports Server (NTRS)

    Vrtilek, J. M.; Gottlieb, C. A.; Langer, W. D.; Thaddeus, P.; Wilson, R. W.

    1985-01-01

    Two rotational transitions of CCD, N = 1-2 at 144 GHz and 2-3 at 216 GHz, were detected in a laboratory glow discharge through deuterated acetylene and helium, after which one, N = 2-1, was detected toward the rich molecular cloud behind the Orion Nebula. The 144 GHz transition is a well-resolved spin doublet split by 55 MHz, the components of which contain hyperfine structure of the order of 1 MHz, so far only partially resolved. From observations toward two positions in Orion, at and near the Kleinmann-Low nebula, the column density of CCD is determined to be 1.8 x 10 to the 13th/sq cm and the isotopic ratio CCD/CCH = 0.05. CCD was not detected at two positions in TMC-1.

  20. Detection and quantification system for monitoring instruments

    DOEpatents

    Dzenitis, John M.; Hertzog, Claudia K.; Makarewicz, Anthony J.; Henderer, Bruce D.; Riot, Vincent J.

    2008-08-12

    A method of detecting real events by obtaining a set of recent signal results, calculating measures of the noise or variation based on the set of recent signal results, calculating an expected baseline value based on the set of recent signal results, determining sample deviation, calculating an allowable deviation by multiplying the sample deviation by a threshold factor, setting an alarm threshold from the baseline value plus or minus the allowable deviation, and determining whether the signal results exceed the alarm threshold.

  1. Online Monitoring System for Performance Fault Detection

    SciTech Connect

    Gioiosa, Roberto; Kestor, Gokcen; Kerbyson, Darren J.

    2014-05-19

    To achieve the exaFLOPS performance within a contain power budget, next supercomputers will feature hundreds of millions of components operating at low- and near-threshold voltage. As the probability that at least one of these components fails during the execution of an application approaches certainty, it seems unrealistic to expect that any run of a scientific application will not experience some performance faults. We believe that there is need of a new generation of light-weight performance and debugging tools that can be used online even during production runs of parallel applications and that can identify performance anomalies during the application execution. In this work we propose the design and implementation of a monitoring system that continuously inspects the evolution of run

  2. Online Monitoring System for Performance Fault Detection

    SciTech Connect

    Gioiosa, Roberto; Kestor, Gokcen; Kerbyson, Darren J.

    2014-12-31

    To achieve the exaFLOPS performance within a contained power budget, next generation supercomputers will feature hundreds of millions of components operating at low- and near-threshold voltage. As the probability that at least one of these components fails during the execution of an application approaches certainty, it seems unrealistic to expect that any run of a scientific application will not experience some performance faults. We believe that there is need of a new generation of light-weight performance and debugging tools that can be used online even during production runs of parallel applications and that can identify performance anomalies during the application execution. In this work we propose the design and implementation of such a monitoring system.

  3. EpiScan: online seizure detection for epilepsy monitoring units.

    PubMed

    Hartmann, Manfred M; Fürbass, Franz; Perko, Hannes; Skupch, Ana; Lackmayer, Katharina; Baumgartner, Christoph; Kluge, Tilmann

    2011-01-01

    An online seizure detection algorithm for long-term EEG monitoring is presented, which is based on a periodic waveform analysis detecting rhythmic EEG patterns and an adaptation module automatically adjusting the algorithm to patient-specific EEG properties. The algorithm was evaluated using 4.300 hours of unselected EEG recordings from 48 patients with temporal lobe epilepsy. For 66% of the patients the algorithm detected 100% of the seizures. A mean sensitivity of 83% was achieved. An average of 7.2 false alarms within 24 hours for unselected EEG makes the algorithm attractive for epilepsy monitoring units. PMID:22255730

  4. Evaluation of change detection techniques for monitoring coastal zone environments

    NASA Technical Reports Server (NTRS)

    Weismiller, R. A.; Kristof, S. J.; Scholz, D. K.; Anuta, P. E.; Momin, S. M.

    1977-01-01

    Development of satisfactory techniques for detecting change in coastal zone environments is required before operational monitoring procedures can be established. In an effort to meet this need a study was directed toward developing and evaluating different types of change detection techniques, based upon computer aided analysis of LANDSAT multispectral scanner (MSS) data, to monitor these environments. The Matagorda Bay estuarine system along the Texas coast was selected as the study area. Four change detection techniques were designed and implemented for evaluation: (1) post classification comparison change detection, (2) delta data change detection, (3) spectral/temporal change classification, and (4) layered spectral/temporal change classification. Each of the four techniques was used to analyze a LANDSAT MSS temporal data set to detect areas of change of the Matagorda Bay region.

  5. Recommendations for the Laboratory-Based Detection of Chlamydia trachomatis and Neisseria gonorrhoeae — 2014

    PubMed Central

    Papp, John R.; Schachter, Julius; Gaydos, Charlotte A.; Van Der Pol, Barbara

    2014-01-01

    . gonorrhoeae culture is required to evaluate suspected cases of gonorrhea treatment failure and to monitor developing resistance to current treatment regimens. Chlamydia culture also should be maintained in some laboratories to monitor future changes in antibiotic susceptibility and to support surveillance and research activities such as detection of lymphogranuloma venereum or rare infections caused by variant or mutated C. trachomatis. PMID:24622331

  6. Early Attempts to Detect the Neutrino at the Cavendish Laboratory

    NASA Astrophysics Data System (ADS)

    Navarro, Jaume

    2006-03-01

    In the 1920s and early 1930s the Cavendish Laboratory in Cambridge was preeminent in experimental research on radioactivity and nuclear physics, with theoretical physics playing a subsidiary role in guiding, but not determining the course of experimental research. Soon after Wolfgang Pauli (1900 1958) proposed his neutrino hypothesis in 1930 to preserve conservation of energy and momentum in beta decay, experiments the first of their kind were carried out in the Cavendish Laboratory to detect Pauli’s elusive particle, but they were abandoned in 1936. I trace these early attempts and suggest reasons for their abandonment, which may contribute to an understanding of the complex way in which theoretical entities are accepted by physicists.

  7. Crack-Detection Experiments on Simulated Turbine Engine Disks in NASA Glenn Research Center's Rotordynamics Laboratory

    NASA Technical Reports Server (NTRS)

    Woike, Mark R.; Abdul-Aziz, Ali

    2010-01-01

    The development of new health-monitoring techniques requires the use of theoretical and experimental tools to allow new concepts to be demonstrated and validated prior to use on more complicated and expensive engine hardware. In order to meet this need, significant upgrades were made to NASA Glenn Research Center s Rotordynamics Laboratory and a series of tests were conducted on simulated turbine engine disks as a means of demonstrating potential crack-detection techniques. The Rotordynamics Laboratory consists of a high-precision spin rig that can rotate subscale engine disks at speeds up to 12,000 rpm. The crack-detection experiment involved introducing a notch on a subscale engine disk and measuring its vibration response using externally mounted blade-tip-clearance sensors as the disk was operated at speeds up to 12 000 rpm. Testing was accomplished on both a clean baseline disk and a disk with an artificial crack: a 50.8-mm- (2-in.-) long introduced notch. The disk s vibration responses were compared and evaluated against theoretical models to investigate how successful the technique was in detecting cracks. This paper presents the capabilities of the Rotordynamics Laboratory, the baseline theory and experimental setup for the crack-detection experiments, and the associated results from the latest test campaign.

  8. Modeling Behavioral Measures of Error Detection in Choice Tasks: Response Monitoring versus Conflict Monitoring

    ERIC Educational Resources Information Center

    Steinhauser, Marco; Maier, Martin; Hubner, Ronald

    2008-01-01

    The present study investigated the mechanisms underlying error detection in the error signaling response. The authors tested between a response monitoring account and a conflict monitoring account. By implementing each account within the neural network model of N. Yeung, M. M. Botvinick, and J. D. Cohen (2004), they demonstrated that both accounts…

  9. Outlier Detection for Patient Monitoring and Alerting

    PubMed Central

    Hauskrecht, Milos; Batal, Iyad; Valko, Michal; Visweswaran, Shyam; Cooper, Gregory F.; Clermont, Gilles

    2012-01-01

    We develop and evaluate a data-driven approach for detecting unusual (anomalous) patient-management decisions using past patient cases stored in electronic health records (EHRs). Our hypothesis is that a patient-management decision that is unusual with respect to past patient care may be due to an error and that it is worthwhile to generate an alert if such a decision is encountered. We evaluate this hypothesis using data obtained from EHRs of 4,486 post-cardiac surgical patients and a subset of 222 alerts generated from the data. We base the evaluation on the opinions of a panel of experts. The results of the study support our hypothesis that the outlier-based alerting can lead to promising true alert rates. We observed true alert rates that ranged from 25% to 66% for a variety of patient-management actions, with 66% corresponding to the strongest outliers. PMID:22944172

  10. Early detection and monitoring of Malaria

    NASA Astrophysics Data System (ADS)

    Rahman, Md Z.; Roytman, Leonid; Kadik, Abdelhamid; Miller, Howard; Rosy, Dilara A.

    2015-05-01

    Global Earth Observation Systems of Systems (GEOSS) are bringing vital societal benefits to people around the globe. In this research article, we engage undergraduate students in the exciting area of space exploration to improve the health of millions of people globally. The goal of the proposed research is to place students in a learning environment where they will develop their problem solving skills in the context of a world crisis (e.g., malaria). Malaria remains one of the greatest threats to public health, particularly in developing countries. The World Health Organization has estimated that over one million die of Malaria each year, with more than 80% of these found in Sub-Saharan Africa. The mosquitoes transmit malaria. They breed in the areas of shallow surface water that are suitable to the mosquito and parasite development. These environmental factors can be detected with satellite imagery, which provide high spatial and temporal coverage of the earth's surface. We investigate on moisture, thermal and vegetation stress indicators developed from NOAA operational environmental satellite data. Using these indicators and collected epidemiological data, it is possible to produce a forecast system that can predict the risk of malaria for a particular geographical area with up to four months lead time. This valuable lead time information provides an opportunity for decision makers to deploy the necessary preventive measures (spraying, treated net distribution, storing medications and etc) in threatened areas with maximum effectiveness. The main objective of the proposed research is to study the effect of ecology on human health and application of NOAA satellite data for early detection of malaria.

  11. Facility effluent monitoring plan for the 222-S Laboratory

    SciTech Connect

    Nickels, J.M.; Warwick, G.J.

    1992-11-01

    A facility effluent monitoring plan is required by the US Department of Energy in DOE Order 5400.1 for any operations that involve hazardous materials and radioactive substances that could impact employee or public safety or the environment. A facility effluent monitoring plan determination was performed during Calendar Year 1991 and the evaluation requires the need for a facility effluent monitoring plan. This document is prepared using the specific guidelines identified in A Guide for Preparing Hanford Site Facility Effluent Monitoring Plans, WHC-EP-0438-1. This facility effluent monitoring plan assesses effluent monitoring systems and evaluates whether they are adequate to ensure the public health and safety as specified in applicable Federal, State, and local requirements. This facility effluent monitoring plan shall ensure long-range integrity of the effluent monitoring systems by requiring an update whenever a new process or operation introduces new hazardous materials or significant radioactive materials. This document must be reviewed annually even if there are no operational changes, and it must be updated, as a minimum, every three years.

  12. Recent Advances in Nanoplasmonic Sensors for Environmental Detection and Monitoring.

    PubMed

    Choi, Inhee

    2016-05-01

    The great attention in environmental pollution urges the development of innovative monitoring system enabling rapid, sensitive, specific detection and easy operation. Recent progress in nanoplasmonic sensors allowing real-time, highly-sensitive, label-free and multiplex detection provides a promising alternative to conventional environmental analyzing techniques. This review summarizes novel nanoplasmonic approaches categorized by optical detection technologies, which include surface plasmon resonance spectroscopy, dark-field nanospectroscopy, Raman spectroscopy, and even naked eyes. The focus of this review will be on how plasmonic nanostructures can be utilized to detect environmental pollutants, and remarkable accomplishments to enhance the detection performances. In addition, we discuss current challenge and future direction for ubiquitous environmental sensing and monitoring. PMID:27483747

  13. Intrusion detection and monitoring for wireless networks.

    SciTech Connect

    Thomas, Eric D.; Van Randwyk, Jamie A.; Lee, Erik J.; Stephano, Amanda; Tabriz, Parisa; Pelon, Kristen; McCoy, Damon (University of Colorado, Boulder); Lodato, Mark; Hemingway, Franklin; Custer, Ryan P.; Averin, Dimitry; Franklin, Jason; Kilman, Dominique Marie

    2005-11-01

    municipal agencies. In short, these Wi-Fi networks are being deployed everywhere. Much thought has been and is being put into evaluating cost-benefit analyses of wired vs. wireless networks and issues such as how to effectively cover an office building or municipality, how to efficiently manage a large network of wireless access points (APs), and how to save money by replacing an Internet service provider (ISP) with 802.11 technology. In comparison, very little thought and money are being focused on wireless security and monitoring for security purposes.

  14. Monitoring of Detection Probability in QNDE Devices for Storage Tanks

    NASA Astrophysics Data System (ADS)

    Michlin, Y. H.

    2005-04-01

    Tightness-testing devices for underground storage tanks have to be monitored for their probability of detection, and that of a false alarm, during exploitation. The monitoring methods used in Israel is presented, and data on the distributions of the leakage measurement results and of fuel temperatures — and on the rates of change of the latter in the course of the measurements, in terms of their effect on accuracy. Other factors are also discussed.

  15. Flood detection/monitoring using adjustable histogram equalization technique.

    PubMed

    Nazir, Fakhera; Riaz, Muhammad Mohsin; Ghafoor, Abdul; Arif, Fahim

    2014-01-01

    Flood monitoring technique using adjustable histogram equalization is proposed. The technique overcomes the limitations (overenhancement, artifacts, and unnatural look) of existing technique by adjusting the contrast of images. The proposed technique takes pre- and postimages and applies different processing steps for generating flood map without user interaction. The resultant flood maps can be used for flood monitoring and detection. Simulation results show that the proposed technique provides better output quality compared to the state of the art existing technique. PMID:24558332

  16. Flood Detection/Monitoring Using Adjustable Histogram Equalization Technique

    PubMed Central

    Riaz, Muhammad Mohsin; Ghafoor, Abdul

    2014-01-01

    Flood monitoring technique using adjustable histogram equalization is proposed. The technique overcomes the limitations (overenhancement, artifacts, and unnatural look) of existing technique by adjusting the contrast of images. The proposed technique takes pre- and postimages and applies different processing steps for generating flood map without user interaction. The resultant flood maps can be used for flood monitoring and detection. Simulation results show that the proposed technique provides better output quality compared to the state of the art existing technique. PMID:24558332

  17. Knolls Atomic Power Laboratory Environmental Monitoring Report, Calendar Year 2003

    SciTech Connect

    2003-12-31

    The effluent and environmental monitoring programs conducted by KAPL at the Knolls and Kesselring Sites are designed to determine the effectiveness of treatment and control methods, to provide measurement of the concentrations in effluents for comparison with applicable standards, and to assess resultant concentrations in the environment. The monitoring programs include analyses of samples of liquid and gaseous effluents for chemical constituents and radioactivity as well as environmental monitoring of air, water, sediment, and fish. Radiation measurements are also made around the perimeter of the Knolls and Kesselring Sites and at off-site background locations.

  18. Reliability of nucleic acid amplification for detection of Mycobacterium tuberculosis: an international collaborative quality control study among 30 laboratories.

    PubMed Central

    Noordhoek, G T; van Embden, J D; Kolk, A H

    1996-01-01

    Nucleic acid amplification to detect Mycobacterium tuberculosis in clinical specimens is increasingly used as a laboratory tool for the diagnosis of tuberculosis. However, the specificity and sensitivity of these tests may be questioned, and no standardized reagents for quality control assessment are available. To estimate the performance of amplification tests for routine diagnosis, we initiated an interlaboratory study involving 30 laboratories in 18 countries. We prepared blinded panels of 20 sputum samples containing no, 100, or 1,000 mycobacterial cells. Each laboratory was asked to detect M. tuberculosis by their routine method of nucleic acid amplification. Only five laboratories correctly identified the presence or absence of mycobacterial DNA in all 20 samples. Seven laboratories detected mycobacterial DNA in all positive samples, and 13 laboratories correctly reported the absence of DNA in the negative samples. Lack of specificity was more of a problem than lack of sensitivity. Reliability was not found to be associated with the use of any particular method. Reliable detection of M. tuberculosis in clinical samples by nucleic acid amplification techniques is possible, but many laboratories do not use adequate quality controls. This study underlines the need for good laboratory practice and reference reagents to monitor the performance of the whole assay, including pretreatment of clinical samples. PMID:8880513

  19. Idaho National Laboratory Cultural Resource Monitoring Report for FY 2009

    SciTech Connect

    Brenda R. Pace; Julie B. Braun

    2009-10-01

    This report describes the cultural resource monitoring activities of the Idaho National Laboratory’s (INL) Cultural Resource Management (CRM) Office during fiscal year 2009 (FY 2009). Throughout the year, thirty-eight cultural resource localities were revisited including: two locations with Native American human remains, one of which is a cave, two additional caves, twenty-two prehistoric archaeological sites, six historic homesteads, two historic stage stations, two historic trails, and two nuclear resources, including Experimental Breeder Reactor-I, which is a designated National Historic Landmark. Several INL project areas were also monitored in FY 2009 to assess project compliance with cultural resource recommendations and monitor the effects of ongoing project activities. Although impacts were documented at a few locations and trespassing citations were issued in one instance, no significant adverse effects that would threaten the National Register eligibility of any resources were observed. Monitoring also demonstrated that several INL projects generally remain in compliance with recommendations to protect cultural resources.

  20. Annual environmental monitoring report of the Lawrence Berkeley Laboratory, 1981

    SciTech Connect

    Schleimer, G.E.

    1982-06-01

    Results for 1981 of the LBL Environmental Monitoring Program are given. Data include monitoring results for accelerator-produced radiation, airborne and waterborne radionuclides, and nonradioactive pollutants. Population doses resulting from LBL operations are given in terms of accelerator-produced and airborne radioactivities. Trends in the environmental impacts of LBL operations are discussed in terms of accelerator-produced, airborne, and waterborne radionuclides. (ERB)

  1. Idaho National Laboratory Cultural Resource Monitoring Report for 2013

    SciTech Connect

    Julie B. Williams; Brenda Pace

    2013-10-01

    This report describes the cultural resource monitoring activities of the Idaho National Laboratory’s (INL) Cultural Resource Management (CRM) Office during 2013. Throughout the year, thirty-eight cultural resource localities were revisited including: two locations with Native American human remains, one of which is also a cave; fourteen additional caves; seven prehistoric archaeological sites ; four historic archaeological sites; one historic trail; one nuclear resource (Experimental Breeder Reactor-I, a designated National Historic Landmark); and nine historic structures located at the Central Facilities Area. Of the monitored resources, thirty-three were routinely monitored, and five were monitored to assess project compliance with cultural resource recommendations along with the effects of ongoing project activities. On six occasions, ground disturbing activities within the boundaries of the Power Burst Facility/Critical Infrastructure Test Range Complex (PBF/CITRC) were observed by INL CRM staff prepared to respond to any additional finds of Native American human remains. In addition, two resources were visited more than once as part of the routine monitoring schedule or to monitor for additional damage. Throughout the year, most of the cultural resources monitored had no visual adverse changes resulting in Type 1determinations. However, Type 2 impacts were noted at eight sites, indicating that although impacts were noted or that a project was operating outside of culturally cleared limitations, cultural resources retained integrity and noted impacts did not threaten National Register eligibility. No new Type 3 or any Type 4 impacts that adversely impacted cultural resources and threatened National Register eligibility were observed at cultural resources monitored in 2013.

  2. Sandia National Laboratories California Environmental Monitoring Program Annual Report.

    SciTech Connect

    Holland, Robert C.

    2007-03-01

    The annual program report provides detailed information about all aspects of the SNL/CA Environmental Monitoring Program for a given calendar year. It functions as supporting documentation to the SNL/CA Environmental Management System Program Manual. The 2006 program report describes the activities undertaken during the past year, and activities planned in future years to implement the Environmental Monitoring Program, one of six programs that supports environmental management at SNL/CA.

  3. Monitoring programs need to take into account imperfect species detectability

    USGS Publications Warehouse

    Kery, M.; Schmid, H.

    2004-01-01

    Biodiversiry monitoring is important to identify biological units in need of conservation and to check the effectiveness of conservation actions. Programs generally monitor species richness and its changes (trend). Usually, no correction is made for imperfect species detectability. Instead, it is assumed that each species present has the same probability of being recorded and that there is no difference in this detectability across space and time, e.g. among observers and habitats. Consequently, species richness is determined by enumeration as the sum of species recorded. In Switzerland, the federal government has recently launched a comprehensive program that aims at detecting changes in biodiversity at all levels of biological integration. Birds are an important part of that program. Since 1999, 23 visits per breeding season are made to each of >250 1 km2 squares to map the territories of all detected breeding bird species. Here, we analyse data from three squares to illustrate the use of capture-recapture models in monitoring to obtain detectability-corrected estimates of species richness and trend. Species detectability averaged only 85%. Hence an estimated 15% of species present remained overlooked even after three visits. Within a square, changes in detectability for different years were of the same magnitude when surveys were conducted by the same observer as when they were by different observers. Estimates of trend were usually biased and community turnover was overestimated when based on enumeration. Here we use bird data as an illustration of methods. However, species detectability for any taxon is unlikely ever to be perfect or even constant across categories to be compared. Therefore, monitoring programs should correct for species detectability.

  4. A Survey of Nursing Home Physicians to Determine Laboratory Monitoring Adverse Drug Event Alert Preferences

    PubMed Central

    Perera, S.; Nace, D.A.; Culley, C.M.; Handler, S.M.

    2014-01-01

    Summary Objective We conducted a survey of nursing home physicians to learn about (1) the laboratory value thresholds that clinical event monitors should use to generate alerts about potential adverse drug events (ADEs); (2) the specific information to be included in the alerts; and (3) the communication modality that should be used for communicating them. Methods Nursing home physician attendees of the 2010 Conference of AMDA: The Society for Post-Acute and Long-Term Care Medicine. Results A total of 800 surveys were distributed; 565 completed surveys were returned and seven surveys were excluded due to inability to verify that the respondents were physicians (a 70% net valid response rate). Alerting threshold preferences were identified for eight laboratory tests. For example, the majority of respondents selected thresholds of ≥ 5.5 mEq/L for hyperkalemia (63%) and ≤ 3.5 without symptoms for hypokalemia (54%). The majority of surveyed physicians thought alerts should include the complete active medication list, current vital signs, previous value of the triggering lab, medication change in the past 30 days, and medication allergies. Most surveyed physicians felt the best way to communicate an ADE alert was by direct phone/voice communication (64%), followed by email to a mobile device (59%). Conclusions This survey of nursing home physicians suggests that the majority prefer alerting thresholds that would generally lead to fewer alerts than if widely accepted standardized laboratory ranges were used. It also suggests a subset of information items to include in alerts, and the physicians’ preferred communication modalities. This information might improve the acceptance of clinical event monitoring systems to detect ADEs in the nursing home setting. PMID:25589905

  5. Health Monitoring System for the SSME-fault detection algorithms

    NASA Technical Reports Server (NTRS)

    Tulpule, S.; Galinaitis, W. S.

    1990-01-01

    A Health Monitoring System (HMS) Framework for the Space Shuttle Main Engine (SSME) has been developed by United Technologies Corporation (UTC) for the NASA Lewis Research Center. As part of this effort, fault detection algorithms have been developed to detect the SSME faults with sufficient time to shutdown the engine. These algorithms have been designed to provide monitoring coverage during the startup, mainstage and shutdown phases of the SSME operation. The algorithms have the capability to detect multiple SSME faults, and are based on time series, regression and clustering techniques. This paper presents a discussion of candidate algorithms suitable for fault detection followed by a description of the algorithms selected for implementation in the HMS and the results of testing these algorithms with the SSME test stand data.

  6. Use of a clinical event monitor to prevent and detect medication errors.

    PubMed Central

    Payne, T. H.; Savarino, J.; Marshall, R.; Hoey, C. T.

    2000-01-01

    Errors in health care facilities are common and often unrecognized. We have used our clinical event monitor to prevent and detect medication errors by scrutinizing electronic messages sent to it when any medication order is written in our facility. A growing collection of medication safety rules covering dose limit errors, laboratory monitoring, and other topics may be applied to each medication order message to provide an additional layer of protection beyond existing order checks, reminders, and alerts available within our computer-based record system. During a typical day the event monitor receives 4802 messages, of which 4719 pertain to medication orders. We have found the clinical event monitor to be a valuable tool for clinicians and quality management groups charged with improving medication safety. PMID:11079962

  7. Idaho National Laboratory Cultural Resource Monitoring Report for FY 2010

    SciTech Connect

    INL Cultural Resource Management Office

    2010-10-01

    This report describes the cultural resource monitoring activities of the Idaho National Laboratory’s (INL) Cultural Resource Management (CRM) Office during fiscal year 2010 (FY 2010). Throughout the year, thirty-three cultural resource localities were revisited, including somethat were visited more than once, including: two locations with Native American human remains, one of which is a cave, two additional caves, twenty-six prehistoric archaeological sites, two historic stage stations, and Experimental Breeder Reactor-I, which is a designated National Historic Landmark. The resources that were monitored included seventeen that are routinely visited and sixteen that are located in INL project areas. Although impacts were documented at a few locations and one trespassing incident (albeit sans formal charges) was discovered, no significant adverse effects that would threaten the National Register eligibility of any resources were observed. Monitoring also demonstrated that several INL projects generally remain in compliance with recommendations to protect cultural resources.

  8. Gunite and associated tanks dry well conductivity monitoring report, Oak Ridge National Laboratory, Oak Ridge, Tennessee, February 1998--December 1998

    SciTech Connect

    1999-04-01

    A waste removal program is being implemented for the Gunite and Associated Tanks Operable Unit at Oak Ridge National Laboratory, Oak Ridge, Tennessee. The waste is being removed by means of remotely operated, in-tank, confined sluicing equipment. During sluicing operations the dry wells adjacent to each of the tanks are instrumented so that potential releases can be detected by means external to the tank. The method of detection is by monitoring the electrical conductivity of the water in the dry well associated with each tank. This report documents the dry well conductivity monitoring data for the period from February 1998 through December 1998. The dry wells monitored during this period include DW-5, DW-6, DW-7, DW-8, DW-9 and DW-10. The conductivity of the water passing through Pump Station 1 (PS1) was also monitored. During this period the sluicing activities at Tank W-6 were initiated and successfully completed. In addition, flight mixers were used to remove wastes from Tank W-5, and sluicing operations were initiated on Tank W-7. Presented in this report are the dry well conductivity, rainfall, tank level, and other appropriate information relevant to the analysis and interpretation of the monitoring data for the reporting period. A thorough analysis of the monitoring results from the six dry wells in the STF and PS1 for the period between February 1998 and December 1998 indicates that no releases have occurred from the gunite tanks being monitored. Overall, the dry well conductivity monitoring continues to provide a robust and sensitive method for detecting potential releases from the gunite tanks and for monitoring seasonal and construction-related changes in the dry well and drain system.

  9. Biofouling detection monitoring devices: status assessment. Final report

    SciTech Connect

    Hillman, R.E.; Anson, D.; Corliss, J.M.; Vigon, B.W.; Gray, R.H.; Bomelburg, H.J.

    1985-03-01

    An inventory of devices to detect and monitor biofouling in power plant condenser systems was prepared. The inventory was developed through a review of manufacturers' product information brochures, a general literature review, and limited personal contact with users and manufacturers. Two macrofouling and seventeen microfouling detection devices were reviewed. A summary analysis of the principal features of each device was prepared. Macrofouling devices are generally simple devices located at or near cooling water intakes. They monitor the growth of larger organisms such as mussels, barnacles, and large seaweeds. Microfouling detectors are usually located in or near the condenser tubes. They detect and monitor the growth of slime films on the tubes. Some of the devices measure changes in heat transfer or pressure drop in the condenser tubes. Other types include condenser simulators, biofilm samplers, or devices that measure the acoustic properties of the fouling films. Most devices are still in the development stage. Of the few available for general use, the type that measures heat transfer and/or pressure drop are developed to a greater degree than the other types. Recommendations for further research into development of a biofouling detection and monitoring devices include a side-by-side field comparison of selected devices, and the continued development of an effective acoustic device.

  10. Attention focusing and anomaly detection in systems monitoring

    NASA Technical Reports Server (NTRS)

    Doyle, Richard J.

    1994-01-01

    Any attempt to introduce automation into the monitoring of complex physical systems must start from a robust anomaly detection capability. This task is far from straightforward, for a single definition of what constitutes an anomaly is difficult to come by. In addition, to make the monitoring process efficient, and to avoid the potential for information overload on human operators, attention focusing must also be addressed. When an anomaly occurs, more often than not several sensors are affected, and the partially redundant information they provide can be confusing, particularly in a crisis situation where a response is needed quickly. The focus of this paper is a new technique for attention focusing. The technique involves reasoning about the distance between two frequency distributions, and is used to detect both anomalous system parameters and 'broken' causal dependencies. These two forms of information together isolate the locus of anomalous behavior in the system being monitored.

  11. Effluent-Monitoring Procedures: Basic Laboratory Skills. Student Reference Manual.

    ERIC Educational Resources Information Center

    Engel, William T.; And Others

    This is one of several short-term courses developed to assist in the training of waste water treatment plant operational personnel in the tests, measurements, and report preparation required for compliance with their NPDES Permits. This Student Reference Manual provides a review of basic mathematics as it applies to the chemical laboratory. The…

  12. In Situ Techniques for Monitoring Electrochromism: An Advanced Laboratory Experiment

    ERIC Educational Resources Information Center

    Saricayir, Hakan; Uce, Musa; Koca, Atif

    2010-01-01

    This experiment employs current technology to enhance and extend existing lab content. The basic principles of spectroscopic and electroanalytical techniques and their use in determining material properties are covered in some detail in many undergraduate chemistry programs. However, there are limited examples of laboratory experiments with in…

  13. Development of a laboratory prototype water quality monitoring system suitable for use in zero gravity

    NASA Technical Reports Server (NTRS)

    Misselhorn, J. E.; Witz, S.; Hartung, W. H.

    1973-01-01

    The development of a laboratory prototype water quality monitoring system for use in the evaluation of candidate water recovery systems and for study of techniques for measuring potability parameters is reported. Sensing techniques for monitoring of the most desirable parameters are reviewed in terms of their sensitivities and complexities, and their recommendations for sensing techniques are presented. Rationale for selection of those parameters to be monitored (pH, specific conductivity, Cr(+6), I2, total carbon, and bacteria) in a next generation water monitor is presented along with an estimate of flight system specifications. A master water monitor development schedule is included.

  14. Proficiency of clinical laboratories in and near Monterrey, Mexico, to detect vancomycin-resistant enterococci.

    PubMed Central

    McDonald, L. C.; Garza, L. R.; Jarvis, W. R.

    1999-01-01

    Early detection of vancomycin-resistant enterococci is important for preventing its spread among hospitalized patients. We surveyed the ability of eight hospital laboratories in and near Monterrey, Mexico, to detect vancomycin resistance in Enterococcus spp. and found that although laboratories can reliably detect high-level vancomycin resistance, many have difficulty detecting low-level resistance. PMID:10081682

  15. [Application of lysosomal detection in marine pollution monitoring: research progress].

    PubMed

    Weng, You-Zhu; Fang, Yong-Qiang; Zhang, Yu-Sheng

    2013-11-01

    Lysosome is an important organelle existing in eukaryotic cells. With the development of the study on the structure and function of lysosome in recent years, lysosome is considered as a target of toxic substances on subcellular level, and has been widely applied abroad in marine pollution monitoring. This paper summarized the biological characteristics of lysosomal marker enzyme, lysosome-autophagy system, and lysosomal membrane, and introduced the principles and methods of applying lysosomal detection in marine pollution monitoring. Bivalve shellfish digestive gland and fish liver are the most sensitive organs for lysosomal detection. By adopting the lysosomal detection techniques such as lysosomal membrane stability (LMS) test, neutral red retention time (NRRT) assay, morphological measurement (MM) of lysosome, immunohistochemical (Ih) assay of lysosomal marker enzyme, and electron microscopy (EM), the status of marine pollution can be evaluated. It was suggested that the lysosome could be used as a biomarker for monitoring marine environmental pollution. The advantages and disadvantages of lysosomal detection and some problems worthy of attention were analyzed, and the application prospects of lysosomal detection were discussed. PMID:24564165

  16. Environmental monitoring and assessment program (EMAP) laboratory methods manual estuaries. Volume 1. Biological and physical analyses

    SciTech Connect

    Strobel, C.J.; Klemm, D.J.; Lobring, L.B.; Eichelberger, J.W.; Alford-Stevens, A.

    1995-08-01

    This document is intended to document analytical methods for use by laboratories conducting analyses for the Environmental Monitoring and Assessment Program-Estuaries. This document is volume I of a two-part series. The second volume of the EMAP-Estuaries Laboratory Methods Manual presents methods for the chemical analyses of sediments and tissue.

  17. MONITORING OF THE ESTROUS CYCLE IN THE LABORATORY RODENT BY VAGINAL LAVAGE

    EPA Science Inventory

    Ovarian cyclicity in a number of laboratory species can be monitored easily and noninvasively by observing changes in the vaginal cytology. his chapter describes the techniques used to collect data in the laboratory rat and mouse and how to interpret the lavages as they are obtai...

  18. Vibration Monitoring Techniques Applied to Detect Damage in Rotating Disks

    NASA Technical Reports Server (NTRS)

    Gyekenyesi, Andrew L.; Sawicki, Jerzy T.

    2002-01-01

    Rotor health monitoring and online damage detection are increasingly gaining the interest of the manufacturers of aircraft engines. This is primarily due to the need for improved safety during operation as well as the need for lower maintenance costs. Applied techniques for detecting damage in and monitoring the health of rotors are essential for engine safety, reliability, and life prediction. The goals of engine safety are addressed within the NASA-sponsored Aviation Safety Program (AvSP). AvSP provides research and technology products needed to help the Federal Aviation Administration and the aerospace industry improve aviation safety. The Nondestructive Evaluation Group at the NASA Glenn Research Center is addressing propulsion health management and the development of propulsion-system-specific technologies intended to detect potential failures prior to catastrophe.

  19. 1982 Environmental monitoring report, Sandia National Laboratories, Albuquerque, New Mexico

    SciTech Connect

    Millard, G.C.; Gray, C.E.; Simmons, T.N.; O'Neal, B.L.

    1983-04-01

    Because radionuclides are potentially released from its research activities, SNL has a continuing environmental monitoring program which analyzes for cesium-137, tritium, uranium, alpha emitter, and beta emitters in water, soil, air, and vegetation. Measured radiation levels in public areas were consistent with local background in 1982. The Albuquerque population received an estimated 0.170 person-rem from airborne radioactive releases, whereas it received greater than 50,400 person-rem from naturally occurring radionuclides.

  20. Idaho National Laboratory Cultural Resource Monitoring Report for FY 2008

    SciTech Connect

    Brenda R. Pace

    2009-01-01

    This report describes the cultural resource monitoring activities of the Idaho National Laboratory’s (INL) Cultural Resource Management (CRM) Office during fiscal year 2008 (FY 2008). Throughout the year, 45 cultural resource localities were revisited including: two locations of heightened Shoshone-Bannock tribal sensitivity, four caves, one butte, twenty-eight prehistoric archaeological sites, three historic homesteads, two historic stage stations, one historic canal construction camp, three historic trails, and Experimental Breeder Reactor-I, which is a designated National Historic Landmark. Several INL project areas were also monitored in FY 2008 to assess project compliance with cultural resource recommendations, confirm the locations of previously recorded cultural resources in relation to project activities, to assess the damage caused by fire-fighting efforts, and to watch for cultural materials during ground disturbing activities. Although impacts were documented at a few locations, no significant adverse effects that would threaten the National Register eligibility of any resource were observed. Monitoring also demonstrated that INL projects generally remain in compliance with recommendations to protect cultural resources

  1. Sepsis Patient Detection and Monitor Based on Auto-BN.

    PubMed

    Jiang, Yu; Sha, Lui; Rahmaniheris, Maryam; Wan, Binhua; Hosseini, Mohammad; Tan, Pengliu; Berlin, Richard B

    2016-04-01

    Sepsis is a life-threatening condition caused by an inappropriate immune response to infection, and is a leading cause of elderly death globally. Early recognition of patients and timely antibiotic therapy based on guidelines improve survival rate. Unfortunately, for those patients, it is often detected late because it is too expensive and impractical to perform frequent monitoring for all the elderly. In this paper, we present a risk driven sepsis screening and monitoring framework to shorten the time of onset detection without frequent monitoring of all the elderly. Within this framework, the sepsis ultimate risk of onset probability and mortality is calculated based on a novel temporal probabilistic model named Auto-BN, which consists of time dependent state, state dependent property, and state dependent inference structures. Then, different stages of a patient are encoded into different states, monitoring frequency is encoded into the state dependent property, and screening content is encoded into different state dependent inference structures. In this way, the screening and monitoring frequency and content can be automatically adjusted when encoding the sepsis ultimate risk into the guard of state transition. This allows for flexible manipulation of the tradeoff between screening accuracy and frequency. We evaluate its effectiveness through empirical study, and incorporate it into existing medical guidance system to improve medical healthcare. PMID:26940673

  2. Growth monitoring as an early detection tool: a systematic review.

    PubMed

    Scherdel, Pauline; Dunkel, Leo; van Dommelen, Paula; Goulet, Olivier; Salaün, Jean-François; Brauner, Raja; Heude, Barbara; Chalumeau, Martin

    2016-05-01

    Growth monitoring of apparently healthy children aims at early detection of serious underlying disorders. However, existing growth-monitoring practices are mainly based on suboptimal methods, which can result in delayed diagnosis of severe diseases and inappropriate referrals. We did a systematic review to address two key and interconnected questions underlying growth monitoring: which conditions should be targeted, and how should abnormal growth be defined? We systematically searched for studies reporting algorithms for growth monitoring in children and studies comparing the performance of new WHO growth charts with that of other growth charts. Among 1556 identified citations, 69 met the inclusion criteria. Six target conditions have mainly been studied: Turner syndrome, coeliac disease, cystic fibrosis, growth hormone deficiency, renal tubular acidosis, and small for gestational age with no catch-up after 2 or 3 years. Seven algorithms to define abnormal growth have been proposed in the past 20 years, but their level of validation is low, and their overall sensitivities and specificities vary substantially; however, the Grote and Saari clinical decision rules seem the most promising. Two studies reported that WHO growth charts had poorer performance compared with other existing growth charts for early detection of target conditions. Available data suggest a large gap between the widespread implementation of growth monitoring and its level of evidence or the clinical implications of early detection of serious disorders in children. Further investigations are needed to standardise the practice of growth monitoring, with a consensus on a few priority target conditions and with internationally validated clinical decision rules to define abnormal growth, including the selection of appropriate growth charts. PMID:26777129

  3. Quarry detection monitoring wells completion report WP-166

    SciTech Connect

    Not Available

    1991-09-01

    The purpose of this report is to document the activities undertaken during implementation of Work Package 166, Quarry Detection Monitoring Wells, for the Weldon Spring Site Remedial action project, Weldon Spring, Missouri. The subcontract specifications should be consulted for specific details regarding this work effort. Analytical parameters for soil samples collected for all but one borehole were analyzed for uranium, thorium, cyanide, nitroaromatics, and all Hazardous Substance List parameters including volatiles, semivolatiles, pesticides, polychlorinated biphenyls (PCBs) and metals. No soil samples were collected at other borehole as per specifications. With Z exceptions, uranium results for all boreholes sampled were at background levels. Nitroaromatics and cyanide were not detected in any of the samples collected. Volatile and semivolatile organics were not detected in the soil samples collected from the boreholes, with the exception of common lab contaminants such as methylene chloride, toluene, acetone, and pathalates. All metals results were either within their natural background ranges or below the detection limit of the instrument. PCB's were not detected within any of the boreholes. Pesticides detected (aldrin and methoxychlor) at one borehole near the surface may be attributed to previous spraying of pesticides on the highway right-of-way. In conclusion, the analytical results show that only uranium was detected in significant quantities; all other results were below the detection limit, very near the detection limit, or within natural background ranges. 1 fig.

  4. Unmanned Aerial Vehicles for Alien Plant Species Detection and Monitoring

    NASA Astrophysics Data System (ADS)

    Dvořák, P.; Müllerová, J.; Bartaloš, T.; Brůna, J.

    2015-08-01

    Invasive species spread rapidly and their eradication is difficult. New methods enabling fast and efficient monitoring are urgently needed for their successful control. Remote sensing can improve early detection of invading plants and make their management more efficient and less expensive. In an ongoing project in the Czech Republic, we aim at developing innovative methods of mapping invasive plant species (semi-automatic detection algorithms) by using purposely designed unmanned aircraft (UAV). We examine possibilities for detection of two tree and two herb invasive species. Our aim is to establish fast, repeatable and efficient computer-assisted method of timely monitoring, reducing the costs of extensive field campaigns. For finding the best detection algorithm we test various classification approaches (object-, pixel-based and hybrid). Thanks to its flexibility and low cost, UAV enables assessing the effect of phenological stage and spatial resolution, and is most suitable for monitoring the efficiency of eradication efforts. However, several challenges exist in UAV application, such as geometrical and radiometric distortions, high amount of data to be processed and legal constrains for the UAV flight missions over urban areas (often highly invaded). The newly proposed UAV approach shall serve invasive species researchers, management practitioners and policy makers.

  5. Real-Time Microbiology Laboratory Surveillance System to Detect Abnormal Events and Emerging Infections, Marseille, France

    PubMed Central

    Abat, Cédric; Chaudet, Hervé; Colson, Philippe; Rolain, Jean-Marc

    2015-01-01

    Infectious diseases are a major threat to humanity, and accurate surveillance is essential. We describe how to implement a laboratory data–based surveillance system in a clinical microbiology laboratory. Two historical Microsoft Excel databases were implemented. The data were then sorted and used to execute the following 2 surveillance systems in Excel: the Bacterial real-time Laboratory-based Surveillance System (BALYSES) for monitoring the number of patients infected with bacterial species isolated at least once in our laboratory during the study periodl and the Marseille Antibiotic Resistance Surveillance System (MARSS), which surveys the primary β-lactam resistance phenotypes for 15 selected bacterial species. The first historical database contained 174,853 identifications of bacteria, and the second contained 12,062 results of antibiotic susceptibility testing. From May 21, 2013, through June 4, 2014, BALYSES and MARSS enabled the detection of 52 abnormal events for 24 bacterial species, leading to 19 official reports. This system is currently being refined and improved. PMID:26196165

  6. Annual environmental monitoring report of the Lawrence Berkeley Laboratory, 1979

    SciTech Connect

    Schleimer, G.E.

    1980-06-01

    Monitoring data obtained for the calendar year 1979 are described, and general trends are discussed. The following areas are covered: accelerator produced radiation; radionuclide measurements and release (atmospheric, water, and sewer sampling); population dose equivalent resulting from LBL operations; and nonradioactive pollutants. Over the past several years the atmospheric sampling program has, with the exception of occasional known releases, yielded data which are within the range of normal background. The surface water program always yields results within the range of normal background. As no substantial changes in the quantities of radionuclides used are anticipated, no changes are expected in these observations.

  7. Laboratory monitoring of P-waves in partially saturated sand

    NASA Astrophysics Data System (ADS)

    Barrière, J.; Bordes, C.; Brito, D.; Sénéchal, P.; Perroud, H.

    2011-12-01

    Seismic data depends on a variety of hydrogeological properties of the prospected porous media such as porosity, permeability and fluid saturation. We have performed a laboratory experiment in the kiloHertz range in order to analyze the role of partial saturation on direct propagating P-waves phase velocity and attenuation. The experiment consists of a sand-filled tank 107 cm x 34 cm x 35cm equipped with accelerometers and water capacitance probes. The P-waves seismic propagation is generated by hitting a steel ball on a granite plate on the one lateral side of the container. Several imbibition/drainage cycles are performed between the water residual saturation and the gas residual saturation. The laboratory seismic data are processed by two Continuous Wavelet Transforms using one real mother wavelet (Mexican hat) and one complex (Morlet) to recover velocity and attenuation as a function of frequency. Phase velocity of direct P-wave decreases with an increase of water content and is quite consistent with the low frequency limit of the Biot's theory both for imbibition and drainage. The interpretation of the P-waves attenuation needs to go beyond the macroscopic fluid flow of Biot's theory and to introduce a viscoelastic contribution linked to the grain to grain overall losses which are described by a constant Q-model. A strong hysteresis between imbibition and drainage is observed and explained by introducing an effective permeability depending on water and gas relative permeabilities (Van Genuchten model).

  8. The NOAA climate monitoring and diagnostics laboratory (CMDL) research program

    SciTech Connect

    Ferguson, E.

    1993-12-31

    The CMDL atmospheric measurement program (knows as GMCC--Global Monitoring for Climate Change, prior to 1990) involves monitoring a variety of environmentally important trace gases at four permanent observations. Mauna Loa, Hawaii, Samoa, South Pole and Barrow, Alaska, as well as numerous other global sites. Shipboard and stratospheric aircraft platforms are also utilized. The greenhouse gases CO{sub 2}, CH{sub 4} and CO are measured and analyzed in order to better understand the global carbon cycle. CFCs, HCFC`s and N{sub 2}O are measured, both because of their greenhouse roles as well as their role in the control of stratospheric ozone. Regular balloon borne measurements of ozone, water vapor and aerosols in the stratosphere, particularly over the South Pole, are contributing to the understanding of stratospheric ozone loss. Lidar and solar transmission measurements are being used to study volcanic aerosols. Some of the most recent results of this program will be described along with the implications related to future climate change.

  9. Inspection and monitoring plan, contaminated groundwater seeps 317/319/ENE Area, Argonne National Laboratory

    SciTech Connect

    1996-10-11

    During the course of completing the Resource Conservation and Recovery Act (RCRA) Facility Investigation (RFI) in the 317/319/East-Northeast (ENE) Area of Argonne National Laboratory-East (ANL-E), groundwater was discovered moving to the surface through a series of groundwater seeps. The seeps are located in a ravine approximately 600 ft south of the ANL-E fence line in Waterfall Glen Forest Preserve. Samples of the seep water were collected and analyzed for selected parameters. Two of the five seeps sampled were found to contain detectable levels of organic contaminants. Three chemical species were identified: chloroform (14--25 {micro}g/L), carbon tetrachloride (56--340 {micro}g/L), and tetrachloroethylene (3--6 {micro}g/L). The other seeps did not contain detectable levels of volatile organics. The nature of the contaminants in the seeps will also be monitored on a regular basis. Samples of surface water flowing through the bottom of the ravine and groundwater emanating from the seeps will be collected and analyzed for chemical and radioactive constituents. The results of the routine sampling will be compared with the concentrations used in the risk assessment. If the concentrations exceed those used in the risk assessment, the risk calculations will be revised by using the higher numbers. This revised analysis will determine if additional actions are warranted.

  10. 1996 LMITCO environmental monitoring program report for the Idaho National Engineering and Environmental Laboratory

    SciTech Connect

    1997-09-01

    This report describes the calendar year 1996 environmental surveillance and compliance monitoring activities of the Lockheed Martin Idaho Technologies Company Environmental Monitoring Program performed at the Idaho National Engineering and Environmental Laboratory (INEEL). Results of sampling performed by the Radiological Environmental Surveillance, Site Environmental Surveillance, Drinking Water, Effluent Monitoring, Storm Water Monitoring, Groundwater Monitoring, and Special Request Monitoring Programs are included in this report. The primary purposes of the surveillance and monitoring activities are to evaluate environmental conditions, to provide and interpret data, to verify compliance with applicable regulations or standards, and to ensure protection of human health and the environment. This report compares 1996 data with program-specific regulatory guidelines and past data to evaluate trends.

  11. Remote sensing and laboratory techniques for monitoring ocean dumping

    NASA Technical Reports Server (NTRS)

    Ohlhorst, C. W.; Johnson, R. W.; Meyer, E. R.

    1977-01-01

    Results of field experiments conducted in the Atlantic Coastal Zone indicate that plumes resulting from ocean dumping of acid waste and sewage sludge have distinguishable spectral characteristics when the radiance of the pollutant is normalized (ratioed to) background ocean water. Acid waste spectra peak between 550-650 nm while sewage sludge spectra have peak values at wavelengths of about 700 nm or greater. Results indicate that identification of acid waste and sewage sludge plumes may be independent of geographical location in the Atlantic Coastal Zone. Radiance ratio curves obtained in the laboratory qualitatively agree with those obtained from field experiments. Results from the July 25, 1977, Galveston Deep Ocean Dump Site experiment show the radiance ratio curve of the biodigested industrial waste to be fairly flat and similar to the radiance ratio curves of sewage sludge line dumps and sewage sludge spot dumps that have been in the water for several hours.

  12. Deformation Monitoring of Materials Under Stress in Laboratory Experiments

    NASA Astrophysics Data System (ADS)

    Skarlatos, D.; Yiatros, S.

    2016-06-01

    Photogrammetry is a valid alternative solution to linear variable differential transformer (LVDT) measurements in structural testing in laboratory conditions. Although the use of LVDTs boasts a high degree of accuracy, on the other hand it is limiting as it offers measurements between two points and it thus might be unable to capture localized deformations and strains over a bigger area of a structural specimen. In this aspect photogrammetry seems to offer certain advantages. Commercial solutions provide limited testing envelopes, while on the other hand, the wide range on new materials need more versatile techniques. Based on the need to develop an in-house photogrammetric toolbox to support several structural and material experiments in the department Advanced Pore Morphology (APM) aluminium foam specimens developed at Fraunhofer IFAM in Germany and cured at CUT, were tested under monotonic compressive load. Data acquisition, analysis and results, along with lessons learnt from the process are presented in this work.

  13. The Cloud Detection and UV Monitoring Experiment (CLUE)

    NASA Technical Reports Server (NTRS)

    Barbier, L.; Loh, E.; Sokolsky, P.; Streitmatter, R.

    2004-01-01

    We propose a large-area, low-power instrument to perform CLoud detection and Ultraviolet monitoring, CLUE. CLUE will combine the W detection capabilities of the NIGHTGLOW payload, with an array of infrared sensors to perform cloud slicing measurements. Missions such as EUSO and OWL which seek to measure UHE cosmic-rays at 1W20 eV use the atmosphere as a fluorescence detector. CLUE will provide several important correlated measurements for these missions, including: monitoring the atmospheric W emissions &om 330 - 400 nm, determining the ambient cloud cover during those W measurements (with active LIDAR), measuring the optical depth of the clouds (with an array of narrow band-pass IR sensors), and correlating LIDAR and IR cloud cover measurements. This talk will describe the instrument as we envision it.

  14. Online change detection: Monitoring land cover from remotely sensed data

    SciTech Connect

    Fang, Yi; Ganguly, Auroop R; Singh, Nagendra; Vijayaraj, Veeraraghavan; Feierabend, Robert Neal; Potere, David T

    2006-01-01

    We present a fast and statistically principled approach to land cover change detection. A reference statistical distribution is fitted to prior data based on off-line analysis, and an adaptive metric based on the exponentially weighted moving average (EWMA) of normal scores derived from p-values are tracked for new or streaming data, leading to alarms for large or sustained change. Methods which can track the origin of the change are also discussed. The approach is illustrated with a geographic application which involves monitoring remotely sensed data to detect changes in the normalized difference vegetation index (NDVI) in near real-time. We use Wal-Mart store openings as a nontraditional way to monitor and validate known cases of NDVI change. The proposed approach performs well on this validation dataset.

  15. Near infrared spectroscopy monitoring in the pediatric cardiac catheterization laboratory.

    PubMed

    Tanidir, Ibrahim Cansaran; Ozturk, Erkut; Ozyilmaz, Isa; Saygi, Murat; Kiplapinar, Neslihan; Haydin, Sertac; Guzeltas, Alper; Odemis, Ender

    2014-10-01

    Near-infrared spectroscopy (NIRS) is a noninvasive method used to evaluate tissue oxygenation. We evaluated the relationship between cerebral and renal NIRS parameters during transcatheter intervention and adverse events in the catheterization room. Between January 1 and May 31, 2012, 123 of 163 pediatric patients undergoing cardiac catheterization were followed by NIRS. All were monitored by electrocardiography, noninvasive blood pressure measurement, pulse oxymetry, initial and final blood lactate level measurement. The number of interventional procedures was 73 (59%). During the procedures, 39 patients experienced a total of 41 adverse events: 18 (19.5%) had desaturation, 10 (8.1%) arrhythmia, three (2.4%) had respiratory difficulty, six (4.8%) had a situation calling for cardiopulmonary resuscitation, three (2.4%) had anemia necessitating transfusion, and one (0.8%) had a cyanotic spell. Cranial NIRS values worsened in 12 (9.8%) and renal measurements worsened in 13 (12.5%) patients. The sensitivity and specificity of a 9% impairment of cranial values were 90 and 61%, respectively, while the corresponding calculations for a 21% fall in renal measurements were 54% sensitivity and 90% specificity. When arrhythmia developed, NIRS values fell simultaneously, while the development of a desaturation problem was heralded by NIRS falling 10-15 s earlier than changes in pulse oxymetry; on improving saturation, NIRS returned to earlier values 10-15 s before pulse oxymetry readings. NIRS monitoring may provide an early warning with regard to complications likely to develop during a procedure. A fall of 9% in cranial NIRS values, or of 21% in renal measurements, should raise clinician awareness. PMID:24404951

  16. Detection of anthropogenic radionuclides by the CA002 monitoring station for the comprehensive test ban treaty.

    PubMed

    Measday, D F; Stocki, T J; Mason, L R; Williams, D L

    2001-02-01

    A worldwide monitoring system for radioactive aerosols is being implemented for verification of the Comprehensive Test Ban Treaty. These 80 stations will detect airborne radioactivity not only from nuclear explosions but also from other anthropogenic and natural sources. A prototype unit has been in operation since April 1996 in Vancouver, British Columbia, Canada. It is a very sensitive system and reports clear signals for natural radioactivity, including cosmogenic 7Be, and the decay products from soil exhalation of 220Rn (thoron). In addition, there have been frequent detections of anthropogenic nuclides, probably coming from three distinct facilities-a medical isotope production center, a major university hospital, and a particle accelerator laboratory--all between 1 and 2 km away from the monitoring station. This experience is discussed to sensitize health physicists to the potential uses of this publicly available information. PMID:11197459

  17. Leakage detection using fiber optics distributed temperature monitoring

    NASA Astrophysics Data System (ADS)

    Nikles, Marc; Vogel, Bernhard H.; Briffod, Fabien; Grosswig, Stephan; Sauser, Florian; Luebbecke, Steffen; Bals, Andre; Pfeiffer, Thomas

    2004-07-01

    The monitoring of temperature profiles over long distance by means of optical fibers represents a highly efficient way to perform leakage detection along pipelines, in dams, dykes, or tanks... Different techniques have been developed taking advantages of the fiber geometry and of optical time domain analysis for the localization of the information. Among fiber optics distributed temperature sensing techniques, Brillouin-based systems have demonstrated to have the best potential for applications over distances up to several tens of kilometers. The key features and performances are reviewed in the present article and a 55km pipeline equipped with a fiber optics leakage detection system is presented as a case study.

  18. Landsat change detection can aid in water quality monitoring

    NASA Technical Reports Server (NTRS)

    Macdonald, H. C.; Steele, K. F.; Waite, W. P.; Shinn, M. R.

    1977-01-01

    Comparison between Landsat-1 and -2 imagery of Arkansas provided evidence of significant land use changes during the 1972-75 time period. Analysis of Arkansas historical water quality information has shown conclusively that whereas point source pollution generally can be detected by use of water quality data collected by state and federal agencies, sampling methodologies for nonpoint source contamination attributable to surface runoff are totally inadequate. The expensive undertaking of monitoring all nonpoint sources for numerous watersheds can be lessened by implementing Landsat change detection analyses.

  19. Local Leak Detection and Health Monitoring of Pressurized Tanks

    NASA Technical Reports Server (NTRS)

    Polzin, Kurt; Witherow, William; Korman, Valentin; Sinko, John; Hendrickson, Adam

    2011-01-01

    An optical gas-detection sensor safely monitors pressurized systems (such as cryogenic tanks) and distribution systems for leaks. This sensor system is a fiber-coupled, solid optical body interferometer that allows for the miniaturized sensing element of the device to be placed in the smallest of recesses, and measures a wide range of gas species and densities (leaks). The deflection of the fringe pattern is detected and recorded to yield the time-varying gas density in the gap. This technology can be used by manufacturers or storage facilities with toxic, hazardous, or explosive gases. The approach is to monitor the change in the index of refraction associated with low-level gas leaks into a vacuum environment. The completion of this work will provide NASA with an enabling capability to detect gas system leaks in space, and to verify that pressurized systems are in a safe (i.e. non-leaking) condition during manned docking and transit operations. By recording the output of the sensor, a time-history of the leak can be constructed to indicate its severity. Project risk is mitigated by having several interferometric geometries and detection techniques available, each potentially leveraging hardware and lessons learned to enhance detectability.

  20. Knolls Atomic Power Laboratory annual environmental monitoring report, calendar year 1997

    SciTech Connect

    1997-12-31

    The results of the effluent and environmental monitoring programs at the three Knolls Atomic Power Laboratory (KAPL) sites are summarized and assessed in this report. The effluent and environmental monitoring programs conducted by KAPL are designed to determine the effectiveness of treatment and control methods, to provide measurement of the concentrations in effluents for comparison with applicable standards, and to assess resultant concentrations in the environment. The monitoring programs include analyses of samples of liquid and gaseous effluents for chemical constituents and radioactivity as well as monitoring of environmental air, water, sediment, and fish. Radiation measurements are also made around the perimeter of each site and at off-site background locations.

  1. RCS propulsion functional path analysis for performance monitoring fault detection and annunciation

    NASA Technical Reports Server (NTRS)

    Keesler, E. L.

    1974-01-01

    The operational flight instrumentation required for performance monitoring and fault detection are presented. Measurements by the burn through monitors are presented along with manifold and helium source pressures.

  2. Remote health monitoring system for detecting cardiac disorders.

    PubMed

    Bansal, Ayush; Kumar, Sunil; Bajpai, Anurag; Tiwari, Vijay N; Nayak, Mithun; Venkatesan, Shankar; Narayanan, Rangavittal

    2015-12-01

    Remote health monitoring system with clinical decision support system as a key component could potentially quicken the response of medical specialists to critical health emergencies experienced by their patients. A monitoring system, specifically designed for cardiac care with electrocardiogram (ECG) signal analysis as the core diagnostic technique, could play a vital role in early detection of a wide range of cardiac ailments, from a simple arrhythmia to life threatening conditions such as myocardial infarction. The system that the authors have developed consists of three major components, namely, (a) mobile gateway, deployed on patient's mobile device, that receives 12-lead ECG signals from any ECG sensor, (b) remote server component that hosts algorithms for accurate annotation and analysis of the ECG signal and (c) point of care device of the doctor to receive a diagnostic report from the server based on the analysis of ECG signals. In the present study, their focus has been toward developing a system capable of detecting critical cardiac events well in advance using an advanced remote monitoring system. A system of this kind is expected to have applications ranging from tracking wellness/fitness to detection of symptoms leading to fatal cardiac events. PMID:26577166

  3. How minimum detectable displacement in a GNSS Monitoring Network change?

    NASA Astrophysics Data System (ADS)

    Hilmi Erkoç, Muharrem; Doǧan, Uǧur; Aydın, Cüneyt

    2016-04-01

    The minimum detectable displacement in a geodetic monitoring network shows the displacement magnitude which may be just discriminated with known error probabilities. This displacement, which is originally deduced from sensitivity analysis, depends on network design, observation accuracy, datum of the network, direction of the displacement and power of the statistical test used for detecting the displacements. One may investigate how different scenarios on network design and observation accuracies influence the minimum detectable displacements for the specified datum, a-priorly forecasted directions and assumed power of the test and decide which scenario is the best or most optimum. It is sometimes difficult to forecast directions of the displacements. In that case, the minimum detectable displacements in a geodetic monitoring network are derived on the eigen-directions associated with the maximum eigen-values of the network stations. This study investigates how minimum detectable displacements in a GNSS monitoring network change depending on the accuracies of the network stations. For this, CORS-TR network in Turkey with 15 stations (a station fixed) is used. The data with 4h, 6h, 12 h and 24 h observing session duration in three sequential days of 2011, 2012 and 2013 were analyzed with Bernese 5.2 GNSS software. The repeatabilities of the daily solutions belonging to each year were analyzed carefully to scale the Bernese cofactor matrices properly. The root mean square (RMS) values for daily repeatability with respect to the combined 3-day solution are computed (the RMS values are generally less than 2 mm in the horizontal directions (north and east) and < 5 mm in the vertical direction for 24 h observing session duration). With the obtained cofactor matrices for these observing sessions, the minimum detectable displacements along the (maximum) eigen directions are compared each other. According to these comparisons, more session duration less minimum detectable

  4. Optical Monitoring and Detection of Spinal Cord Ischemia

    PubMed Central

    Mesquita, Rickson C.; D’Souza, Angela; Bilfinger, Thomas V.; Galler, Robert M.; Emanuel, Asher; Schenkel, Steven S.; Yodh, Arjun G.; Floyd, Thomas F.

    2013-01-01

    Spinal cord ischemia can lead to paralysis or paraparesis, but if detected early it may be amenable to treatment. Current methods use evoked potentials for detection of spinal cord ischemia, a decades old technology whose warning signs are indirect and significantly delayed from the onset of ischemia. Here we introduce and demonstrate a prototype fiber optic device that directly measures spinal cord blood flow and oxygenation. This technical advance in neurological monitoring promises a new standard of care for detection of spinal cord ischemia and the opportunity for early intervention. We demonstrate the probe in an adult Dorset sheep model. Both open and percutaneous approaches were evaluated during pharmacologic, physiological, and mechanical interventions designed to induce variations in spinal cord blood flow and oxygenation. The induced variations were rapidly and reproducibly detected, demonstrating direct measurement of spinal cord ischemia in real-time. In the future, this form of hemodynamic spinal cord diagnosis could significantly improve monitoring and management in a broad range of patients, including those undergoing thoracic and abdominal aortic revascularization, spine stabilization procedures for scoliosis and trauma, spinal cord tumor resection, and those requiring management of spinal cord injury in intensive care settings. PMID:24358279

  5. Improvements in atrial fibrillation detection for real-time monitoring.

    PubMed

    Babaeizadeh, Saeed; Gregg, Richard E; Helfenbein, Eric D; Lindauer, James M; Zhou, Sophia H

    2009-01-01

    Electrocardiographic (ECG) monitoring plays an important role in the management of patients with atrial fibrillation (AF). Automated real-time AF detection algorithm is an integral part of ECG monitoring during AF therapy. Before and after antiarrhythmic drug therapy and surgical procedures require ECG monitoring to ensure the success of AF therapy. This article reports our experience in developing a real-time AF monitoring algorithm and techniques to eliminate false-positive AF alarms. We start by designing an algorithm based on R-R intervals. This algorithm uses a Markov modeling approach to calculate an R-R Markov score. This score reflects the relative likelihood of observing a sequence of R-R intervals in AF episodes versus making the same observation outside AF episodes. Enhancement of the AF algorithm is achieved by adding atrial activity analysis. P-R interval variability and a P wave morphology similarity measure are used in addition to R-R Markov score in classification. A hysteresis counter is applied to eliminate short AF segments to reduce false AF alarms for better suitability in a monitoring environment. A large ambulatory Holter database (n = 633) was used for algorithm development and the publicly available MIT-BIH AF database (n = 23) was used for algorithm validation. This validation database allowed us to compare our algorithm performance with previously published algorithms. Although R-R irregularity is the main characteristic and strongest discriminator of AF rhythm, by adding atrial activity analysis and techniques to eliminate very short AF episodes, we have achieved 92% sensitivity and 97% positive predictive value in detecting AF episodes, and 93% sensitivity and 98% positive predictive value in quantifying AF segment duration. PMID:19608194

  6. Environmental Monitoring Plan for Waste Area Grouping 6 at Oak Ridge National Laboratory, Oak Ridge, Tennessee

    SciTech Connect

    Not Available

    1993-09-01

    This document presents the Environmental Monitoring Plan (EMP) for Waste Area Grouping (WAG) 6 at the Oak Ridge National Laboratory (ORNL). Based on the results of the Resource Conservation and Recovery Act (RCRA) Facility Investigation (RFI) and on subsequent discussions with regulators, a decision was made to defer implementing source control remedial measures at the WAG. The alternative selected to address the risks associated with WAG 6 involves maintenance of site access controls prevent public exposure to on-site contaminants, continued monitoring of contaminant releases determine if source control measures are required, and development of technologies that could support the final remediation of WAG 6. Although active source control measures are not being implemented at WAG 6, environmental monitoring is necessary to ensure that any potential changes in contaminant release from the WAG are identified early enough to take appropriate action. Two types of environmental monitoring will be conducted: baseline monitoring and annual routine monitoring. The baseline monitoring will be conducted to establish the baseline contaminant release conditions at the WAG, confirm the site-related chemicals of concern (COCs), and gather data to confirm the site hydrologic model. The baseline monitoring is expected to begin in 1994 and last for 12--18 months. The annual routine monitoring will consist of continued sampling and analyses of COCs to determine off-WAG contaminant flux and risk, identify mills in releases, and confirm the primary contributors to risk. The annual routine monitoring will continue for {approximately} 4 years after completion of the baseline monitoring.

  7. Damage detection and health monitoring of operational structures

    SciTech Connect

    James, G.; Mayes, R.; Carne, T.; Reese, G.

    1994-09-01

    Initial damage detection/health monitoring experiments have been performed on three different operational structures: a fracture critical bridge, a composite wind turbine blade, and an aging aircraft. An induced damage test was performed on the Rio Grande/I40 bridge before its demolition. The composite wind turbine test was fatgued to failure with periodic modal testing performed throughout the testing. The front fuselage of a DC-9 aircraft was used as the testbed for an induced damage test. These tests have yielded important insights into techniques for experimental damage detection on real structures. Additionally, the data are currently being used with current damage detection algorithms to further develop the numerical technology. State of the art testing technologies such as, high density modal testing, scanning laser vibrometry and natural excitation testing have also been utilized for these tests.

  8. Monitoring Whooping Crane Abundance Using Aerial Surveys: Influences on Detectability

    PubMed Central

    Strobel, Bradley N; Butler, Matthew J

    2014-01-01

    The whooping crane (Grus americana), an endangered species, has been counted on its winter grounds in Texas, USA, since 1950 using fixed-wing aircraft. Many shortcomings of the traditional survey technique have been identified, calling into question its efficacy, defensibility, repeatability, and usefulness into the future. To improve and standardize monitoring effort, we began investigating new survey techniques. Here we focus on efficacy of line transect-based distance sampling during aerial surveys. We conducted a preliminary test of distance sampling during winter 2010–2011 while flying the traditional survey, which indicated that detectability within 500 m of transects was 0.558 (SE = 0.031). We then used an experimental decoy survey to evaluate impacts of observer experience, sun position, distance from transect, and group size on detectability. Our results indicated decoy detectability increased with group size and exhibited a quadratic relationship with distance likely due to pontoons on the aircraft. We found that detectability was 2.704 times greater when the sun was overhead and 3.912 times greater when the sun was at the observer's back than when it was in the observer's eyes. We found that an inexperienced observer misclassified non-target objects more often than an experienced observer. During the decoy experiment we used marks on the struts to categorize distances into intervals, but we found that observers misclassified distances 46.7% of the time (95% CI = 37.0–56.6%). Also, we found that detectability of individuals within detected groups was affected by group size and distance from transect. We discuss how these results inform design and implementation of future whooping crane monitoring efforts. Published 2013. This article is a U.S. Government work and is in the public domain in the USA. PMID:26388657

  9. Passive vapor monitoring of underground storage tanks for leak detection.

    PubMed

    Weber, D; Schwille, F

    1991-02-01

    Passive vapor monitoring of underground storage tanks (USTs) containing volatile hydrocarbons at locations external to the tank (an external system) is touted as a fast and effective method of leak detection. However, major gaps remain in our knowledge of the physical processes that relate a measured vapor concentration to the leak rate, thus making network design according to a quantitative design criterion nearly impossible, and differentiation between surface spills and a leaking UST requires certain levels of sophistication in the leak detection system and in the analysis that are not usually available. Heavier-than-air vapors from the constituents of stored hydrocarbons could result in a density-driven convective propagation component that complicates the design of leak detection systems, and finally, detection times are highly sensitive to concentration detection threshold levels set by the system. The use of inadequate systems and analyses can lead to either wasted efforts or excessive subsurface contamination. This paper discusses the physical processes involved, explores the above aspects of external passive vapor leak detection design, and suggests some alternatives as they pertain to gasoline service stations. PMID:24241886

  10. Laboratory validation of the IMEEDS nuclear detection suite

    SciTech Connect

    Bandong, B. B.; Volpe, A. M.

    1998-12-17

    There are naturally occurring radionuclides in the ocean that are derived from cosmic ray interaction in the atmosphere and weathering of crustal rocks on land and under the sea. In addition, man-made radioisotopes are present as a consequence of mining, processing, enrichment, re-processing and testing of fissile nuclear material. The distribution of radioisotopes in natural waters is a function of the chemical properties of the elements and the physico-chemical properties of the medium (Harvey et al., 1990; von Gunten and Benes, 1995). To improve analytical detection levels, the sampling system described in this report is capable of processing hundreds of liters of seawater rapidly, and isolating, or pre-concentrating radionuclides found on particle, colloidal and dissolved phases. Results for a variety of trace elements and radiocesium in river and coastal waters processed through this sampler system are described in a companion report (Field Test of the Radionuclide Sampling System). The previous report discussed fraction of elements and radionuclides between the dissolved and solid phases in natural waters that show large salinity and turbidity variation. The following report describes results for laboratory tests using identical natural waters that were spiked with a broad suite of traceable reference gamma-emitting radioisotopes. These isotopes are man-made, and they are found in natural waters only as a consequence of human activity. The spiked water samples were processed through the sampler system, and radionuclides in the solid and dissolved phases were analyzed directly by gamma spectrometry without further extraction using mineral acids and solvents. Radioisotope abundance in the different samples provide additional information on partitioning in the environment, as well as the efficiency, or effective recovery of isotopes in waters processed through the sampler. The objective of this test is to quantify extraction efficiency for a suite of

  11. Electric conductivity for laboratory and field monitoring of induced partial saturation (IPS) in sands

    NASA Astrophysics Data System (ADS)

    Kazemiroodsari, Hadi

    Liquefaction is loss of shear strength in fully saturated loose sands caused by build-up of excess pore water pressure, during moderate to large earthquakes, leading to catastrophic failures of structures. Currently used liquefaction mitigation measures are often costly and cannot be applied at sites with existing structures. An innovative, practical, and cost effective liquefaction mitigation technique titled "Induced Partial Saturation" (IPS) was developed by researchers at Northeastern University. The IPS technique is based on injection of sodium percarbonate solution into fully saturated liquefaction susceptible sand. Sodium percarbonate dissolves in water and breaks down into sodium and carbonate ions and hydrogen peroxide which generates oxygen gas bubbles. Oxygen gas bubbles become trapped in sand pores and therefore decrease the degree of saturation of the sand, increase the compressibility of the soil, thus reduce its potential for liquefaction. The implementation of IPS required the development and validation of a monitoring and evaluation technique that would help ensure that the sands are indeed partially saturated. This dissertation focuses on this aspect of the IPS research. The monitoring system developed was based on using electric conductivity fundamentals and probes to detect the transport of chemical solution, calculate degree of saturation of sand, and determine the final zone of partial saturation created by IPS. To understand the fundamentals of electric conductivity, laboratory bench-top tests were conducted using electric conductivity probes and small specimens of Ottawa sand. Bench-top tests were used to study rate of generation of gas bubbles due to reaction of sodium percarbonate solution in sand, and to confirm a theory based on which degree of saturation were calculated. In addition to bench-top tests, electric conductivity probes were used in a relatively large sand specimen prepared in a specially manufactured glass tank. IPS was

  12. Testing the applicability of rapid on-site enzymatic activity detection for surface water monitoring

    NASA Astrophysics Data System (ADS)

    Stadler, Philipp; Vogl, Wolfgang; Juri, Koschelnik; Markus, Epp; Maximilian, Lackner; Markus, Oismüller; Monika, Kumpan; Peter, Strauss; Regina, Sommer; Gabriela, Ryzinska-Paier; Farnleitner Andreas, H.; Matthias, Zessner

    2015-04-01

    On-site detection of enzymatic activities has been suggested as a rapid surrogate for microbiological pollution monitoring of water resources (e.g. using glucuronidases, galactosidases, esterases). Due to the possible short measuring intervals enzymatic methods have high potential as near-real time water quality monitoring tools. This presentation describes results from a long termed field test. For twelve months, two ColiMinder devices (Vienna Water Monitoring, Austria) for on-site determination of enzymatic activity were tested for stream water monitoring at the experimental catchment HOAL (Hydrological Open Air Laboratory, Center for Water Resource Systems, Vienna University of Technology). The devices were overall able to follow and reflect the diverse hydrological and microbiological conditions of the monitored stream during the test period. Continuous data in high temporal resolution captured the course of enzymatic activity in stream water during diverse rainfall events. The method also proofed sensitive enough to determine diurnal fluctuations of enzymatic activity in stream water during dry periods. The method was able to capture a seasonal trend of enzymatic activity in stream water that matches the results gained from Colilert18 analysis for E. coli and coliform bacteria of monthly grab samples. Furthermore the comparison of ColiMinder data with measurements gained at the same test site with devices using the same method but having different construction design (BACTcontrol, microLAN) showed consistent measuring results. Comparative analysis showed significant differences between measured enzymatic activity (modified fishman units and pmol/min/100ml) and cultivation based analyses (most probable number, colony forming unit). Methods of enzymatic activity measures are capable to detect ideally the enzymatic activity caused by all active target bacteria members, including VBNC (viable but nonculturable) while cultivation based methods cannot detect VBNC

  13. New methods in ambulatory blood pressure monitoring: interactive monitoring and detection of posture and movement patterns.

    PubMed

    Prill, Thomas; Fahrenberg, Jochen

    2007-08-01

    Psychophysiological monitoring can be used to assess emotional reactivity in cardiovascular measures. Since blood pressure (BP) variability in daily life is primarily caused by physical activity, metabolic and nonmetabolic effects are confounded. A newly developed method of multiple accelerometry allows for the control of such unwanted variances by continuously detecting posture, general activity, and distinct movement patterns. Contingent on episodes of additional heart rate (AHR), an indicator of emotional reactivity, BP measurements can be triggered and participants prompted to enter their current mood in a handheld PC. To evaluate both new methods for BP research, we performed 24-h ambulatory monitoring with 40 normotensive student participants, an evaluation designed to include standard settings for a controlled comparison (library vs. cinema). Findings indicated that the group at the cinema showed higher values of AHR, but group differences in BP were not observed. On the whole, such multiple accelerometry and interactive monitoring appear to be useful methods in behavior research. PMID:17958150

  14. System and process for detecting and monitoring surface defects

    NASA Technical Reports Server (NTRS)

    Mueller, Mark K. (Inventor)

    1994-01-01

    A system and process for detecting and monitoring defects in large surfaces such as the field joints of the container segments of a space shuttle booster motor. Beams of semi-collimated light from three non-parallel fiber optic light panels are directed at a region of the surface at non-normal angles of expected incidence. A video camera gathers some portion of the light that is reflected at an angle other than the angle of expected reflectance, and generates signals which are analyzed to discern defects in the surface. The analysis may be performed by visual inspection of an image on a video monitor, or by inspection of filtered or otherwise processed images. In one alternative embodiment, successive predetermined regions of the surface are aligned with the light source before illumination, thereby permitting efficient detection of defects in a large surface. Such alignment is performed by using a line scan gauge to sense the light which passes through an aperture in the surface. In another embodiment a digital map of the surface is created, thereby permitting the maintenance of records detailing changes in the location or size of defects as the container segment is refurbished and re-used. The defect detection apparatus may also be advantageously mounted on a fixture which engages the edge of a container segment.

  15. Impact of Laboratory Practices on Interlaboratory Variability in Therapeutic Drug Monitoring of Immunosuppressive Drugs.

    PubMed

    Christians, Uwe; Vinks, Alexander A; Langman, Loralie J; Clarke, William; Wallemacq, Pierre; van Gelder, Teun; Renjen, Varun; Marquet, Pierre; Meyer, Eric J

    2015-12-01

    The immunosuppressants cyclosporine, tacrolimus, sirolimus, everolimus, and probably also mycophenolic acid require therapeutic drug monitoring (TDM)-guided dosing to ensure that blood concentrations are kept within the target range in transplant patients. Reliable, accurate, and precise test methods are therefore essential to effectively monitor levels and to make proper dose adjustments. Data from proficiency testing programs have shown substantial interlaboratory variability. Only few attempts have been made to study the underlying causes. The aim of this study was to systematically document current practices used for immunosuppressant drug TDM in clinical laboratories and identify methodological and practice differences, which may cause the variability observed among laboratories. Data collection was primarily conducted by a structured Web-based survey. Invitations to participate in the survey were distributed to clinical laboratories providing immunosuppressant drug TDM. Surveys were completed by 76 laboratories in 14 countries. The results of our survey suggest that there are 3 main reasons for interlaboratory variability: (1) lack of standardization of laboratory procedures and workflows starting with sample collection and handling, (2) lack of use of appropriate reference materials (eg, isotope-labeled internal standards for liquid chromatography-tandem mass spectroscopy), and (3) poor compliance with internationally accepted good laboratory practice guidelines (eg, related to quality control, quality assurance, validation, training of personnel). The results of the survey also suggest that interlaboratory variability is a multifactorial problem. Technical-level consensus on laboratory operational procedures, quality systems, and personnel training will be of great importance to improve quality and interlaboratory comparability. PMID:26291980

  16. Stability of monitoring weak changes in multiply scattering media with ambient noise correlation: laboratory experiments.

    PubMed

    Hadziioannou, Céline; Larose, Eric; Coutant, Olivier; Roux, Philippe; Campillo, Michel

    2009-06-01

    Previous studies have shown that small changes can be monitored in a scattering medium by observing phase shifts in the coda. Passive monitoring of weak changes through ambient noise correlation has already been applied to seismology, acoustics, and engineering. Usually, this is done under the assumption that a properly reconstructed Green function (GF), as well as stable background noise sources, is necessary. In order to further develop this monitoring technique, a laboratory experiment was performed in the 2.5 MHz range in a gel with scattering inclusions, comparing an active (pulse-echo) form of monitoring to a passive (correlation) one. Present results show that temperature changes in the medium can be observed even if the GF of the medium is not reconstructed. Moreover, this article establishes that the GF reconstruction in the correlations is not a necessary condition: The only condition to monitoring with correlation (passive experiment) is the relative stability of the background noise structure. PMID:19507951

  17. Accounting for Incomplete Species Detection in Fish Community Monitoring

    SciTech Connect

    McManamay, Ryan A; Orth, Dr. Donald J; Jager, Yetta

    2013-01-01

    Riverine fish assemblages are heterogeneous and very difficult to characterize with a one-size-fits-all approach to sampling. Furthermore, detecting changes in fish assemblages over time requires accounting for variation in sampling designs. We present a modeling approach that permits heterogeneous sampling by accounting for site and sampling covariates (including method) in a model-based framework for estimation (versus a sampling-based framework). We snorkeled during three surveys and electrofished during a single survey in suite of delineated habitats stratified by reach types. We developed single-species occupancy models to determine covariates influencing patch occupancy and species detection probabilities whereas community occupancy models estimated species richness in light of incomplete detections. For most species, information-theoretic criteria showed higher support for models that included patch size and reach as covariates of occupancy. In addition, models including patch size and sampling method as covariates of detection probabilities also had higher support. Detection probability estimates for snorkeling surveys were higher for larger non-benthic species whereas electrofishing was more effective at detecting smaller benthic species. The number of sites and sampling occasions required to accurately estimate occupancy varied among fish species. For rare benthic species, our results suggested that higher number of occasions, and especially the addition of electrofishing, may be required to improve detection probabilities and obtain accurate occupancy estimates. Community models suggested that richness was 41% higher than the number of species actually observed and the addition of an electrofishing survey increased estimated richness by 13%. These results can be useful to future fish assemblage monitoring efforts by informing sampling designs, such as site selection (e.g. stratifying based on patch size) and determining effort required (e.g. number of

  18. Detecting RFI Through Integrity Monitoring at a DGPS Reference Station

    NASA Astrophysics Data System (ADS)

    Yun, Youngsun; Kee, Changdon; Rife, Jason; Luo, Ming; Pullen, Sam; Enge, Per

    Because GPS is a radio navigation system which has a very low power level, it is vulnerable to RFI. Excessive RFI could cause receiver performance degradation, such as degradation of position accuracy, loss of lock and increased acquisition time. After GPS modernization plans introduce dual-frequency civil signals to mitigate ionospheric errors, RFI will remain as one of the dominant threats for differential GPS navigation systems. Examples of safety-critical civil aviation and military missions threatened by RFI include the Local Area Augmentation System (LAAS) and the Joint Precision Approach and Landing System (JPALS). This paper focuses on RFI mitigation through integrity monitoring for a DGPS system like LAAS or JPALS. The mitigation strategy consists of two parts. First, the paper develops a new RFI detection method, using a raw divergence statistic. Second, the paper investigates strategies for maintaining integrity in the case that RFI is detected.

  19. Oil spill disasters detection and monitoring by optical satellite data

    NASA Astrophysics Data System (ADS)

    Livia Grimaldi, Caterina Sara; Coviello, Irina; Lacava, Teodosio; Pergola, Nicola; Tramutoli, Valerio

    2010-05-01

    Marine oil spill disasters may be related to natural hazards, when storms and hurricanes cause the sinking of tankers carrying crude or refined oil, as well as to human action, as illegal discharges, assessment errors (failures or collisions) or acts of warfare. Their consequence has a devastating effects on the marine and coastal environment. In order to reduce the environmental impact of such kind of hazard, giving to local authorities necessary information of pollution entity and evolution, timely detection and continuously updated information are fundamental. Satellite remote sensing can give a significant contribution in such a direction. Nowadays, SAR (Synthetic Aperture Radar) technology has been recognized as the most efficient for oil spill detection and description, thanks to the high spatial resolution and all-time/weather capability of the present operational sensors. Anyway, the actual SARs revisiting time does not allow a rapid detection and near real-time monitoring of these phenomena at global scale. The COSMO-Skymed Italian dual-mission (expected in the 2010) will overcome this limitation improving the temporal resolution until 12 hours by a SAR constellation of four satellites, but several open questions regarding costs and global delivery policy of such data, might prevent their use in an operational context. Passive optical sensors, on board meteorological satellites, thanks to their high temporal resolution (from a few hours to 15 minutes, depending on the characteristics of the platform/sensor), may represent, at this moment, a suitable SAR alternative/complement for oil spill detection and monitoring. Up to now, some techniques have been proposed for mapping known oil spill discharges monitoring using optical satellite data, on the other hand, reliable satellite methods for an automatic and timely detection of oil spill are still currently missing. Existing methods, in fact, can localize the presence of an oil spill only after an alert and

  20. MOBILE LABORATORY FOR ON-SITE MONITORING OF HAZARDOUS WASTE INCINERATORS

    EPA Science Inventory

    The report discusses: the development of EPA's Hazardous Air Pollutants Mobile Laboratory (HAPML), equipped with monitors for on-line analysis of inorganic and organic stack gas emissions and instrumentation including a gas chromatograph and mass spectrometer (GC/MS); results fro...

  1. Mitigation Monitoring and Reporting Program for continued operation of Lawrence Livermore National Laboratory

    SciTech Connect

    Not Available

    1992-08-01

    A Mitigation Monitoring and Reporting Program, required by the California Environmental Quality Act, was developed by UC as part of the Final EIS/EIR process. This document describing the program is a companion to the Final Environmental Impact Statement/Environmental Impact Report (EIS/EIR) for the Continued Operation of Lawrence Livermore National Laboratory (LLNL) and Sandia National Laboratories, Livermore (SNL, Livermore). The Final EIS/EIR analyzes the potential environmental impacts of the proposed action, which for the purposes of NEPA is: continued operation, including near-term (within 5 to 1 0 years) proposed projects, of LLNL and SNL, Livermore. The proposed action for the EIR is the renewal of the contract between DOE and UC for UC`s continued operation and management of LLNL. The Mitigation Monitoring and Reporting Program is for implementing and monitoring progress of measures taken to mitigate the significant impacts of the proposed action. A complete description of the impacts and proposed mitigations is in Section 5 of Volume I of the Final EIS/EIR. This report summarizes the mitigation measures, identifies the responsible party at the Laboratory for implementing the mitigation measure, states when monitoring will be implemented, when the mitigation measure will be in place and monitoring completed, and who will verify that the mitigation measure was implemented.

  2. Adapting Raman Spectra from Laboratory Spectrometers to Portable Detection Libraries

    SciTech Connect

    Weatherall, James; Barber, Jeffrey B.; Brauer, Carolyn S.; Johnson, Timothy J.; Su, Yin-Fong; Ball, Christopher D.; Smith, Barry; Cox, Rick; Steinke, Robert; McDaniel, Patricia; Wasserzug, Louis

    2013-02-01

    Raman spectral data collected with high-resolution laboratory spectrometers are processed into a for- mat suitable for importing as a user library on a 1064nm DeltaNu rst generation, eld-deployable spectrometer prototype. The two laboratory systems used are a 1064nm Bruker spectrometer and a 785nm Kaiser spectrometer. The steps taken to compensate for device-dependent spectral resolution, wavenumber shifts between instruments, and wavenumber sensitivity variation are described.

  3. Sensitivities of five alpha continuous air monitors for detection of airborne sup 239 Pu

    SciTech Connect

    McIsaac, C.V.; Amaro, C.R.

    1992-07-01

    Results of measurements of the sensitivities of five alpha continuous air monitors (CAMs) for detection of airborne {sup 239}Pu are presented. Four commercially available alpha CAMs (Kurz model 8311, Merlin Gerin Edgar, RADeCO model 452, and Victoreen model 758) and a prototype alpha CAM currently in use at Argonne National Laboratory- West (ANL-W) were tested sampling natural ambient air and laboratory-generated atmospheres laden with either blank dust or dust containing nCi/g concentrations of {sup 239}Pu. Cumulative alpha spectra were stored at 30 or 60 minute intervals during each sampling and were subsequently analyzed using three different commonly used alpha spectrum analysis algorithms. The effect of airborne dust concentration and sample filter porosity on detector resolution and sensitivity for airborne {sup 239}Pu are described.

  4. Sensitivities of five alpha continuous air monitors for detection of airborne {sup 239}Pu

    SciTech Connect

    McIsaac, C.V.; Amaro, C.R.

    1992-07-01

    Results of measurements of the sensitivities of five alpha continuous air monitors (CAMs) for detection of airborne {sup 239}Pu are presented. Four commercially available alpha CAMs (Kurz model 8311, Merlin Gerin Edgar, RADeCO model 452, and Victoreen model 758) and a prototype alpha CAM currently in use at Argonne National Laboratory- West (ANL-W) were tested sampling natural ambient air and laboratory-generated atmospheres laden with either blank dust or dust containing nCi/g concentrations of {sup 239}Pu. Cumulative alpha spectra were stored at 30 or 60 minute intervals during each sampling and were subsequently analyzed using three different commonly used alpha spectrum analysis algorithms. The effect of airborne dust concentration and sample filter porosity on detector resolution and sensitivity for airborne {sup 239}Pu are described.

  5. Study of minimum detection limit of TLD personnel monitoring system in India.

    PubMed

    Sneha, C; Pradhan, S M; Adtani, M M

    2010-09-01

    Personnel monitoring of radiation workers in India is carried out using a thermoluminescence dosemeter (TLD) system based on CaSO(4):Dy Teflon TLD disc. The dose due to occupational exposure for a majority of radiation workers is very small and hence is reported as zero. In view of this the detection of low levels of occupational dose over and above a variable background assumes great importance. The present values of reporting levels are based on the standard deviations of annealed dosemeters and therefore are fixed irrespective of period of use and background radiation levels. The validity of these levels is investigated under laboratory conditions. The laboratory values of standard deviations cannot be used as an indication of the imprecision that occurs during service. Therefore, the validity of the reporting levels is also investigated for control dosemeters used in routine service. PMID:20511403

  6. Trace gas monitoring with infrared laser-based detection schemes

    NASA Astrophysics Data System (ADS)

    Sigrist, M. W.; Bartlome, R.; Marinov, D.; Rey, J. M.; Vogler, D. E.; Wächter, H.

    2008-02-01

    The success of laser-based trace gas sensing techniques crucially depends on the availability and performance of tunable laser sources combined with appropriate detection schemes. Besides near-infrared diode lasers, continuously tunable midinfrared quantum cascade lasers and nonlinear optical laser sources are preferentially employed today. Detection schemes are based on sensitive absorption measurements and comprise direct absorption in multi-pass cells as well as photoacoustic and cavity ringdown techniques in various configurations. We illustrate the performance of several systems implemented in our laboratory. These include time-resolved multicomponent traffic emission measurements with a mobile CO2-laser photoacoustic system, a diode-laser based cavity ringdown device for measurements of impurities in industrial process control, isotope ratio measurements with a difference frequency (DFG) laser source combined with balanced path length detection, detection of methylamines for breath analysis with both a near-IR diode laser and a DFG source, and finally, acetone measurements with a heatable multipass cell intended for vapor phase studies on doping agents in urine samples.

  7. Leak detection by acoustic emission monitoring. Phase 1: Feasibility study

    NASA Astrophysics Data System (ADS)

    Lichtenstein, Bernard; Winder, A. A.

    1994-05-01

    This investigation was conducted to determine the feasibility of detecting leaks from underground storage tanks or pipelines using acoustic emissions. An extensive technical literature review established that distinguishable acoustic emission signals will be generated when a storage tank is subjected to deformation stresses. A parametric analysis was performed which indicated that leak rates less than 0.1 gallons per hour can be detected for leak sizes less than 1/32 inch with 99% probability if the transient signals were sensed with an array of accelerometers (cemented to the tank or via acoustic waveguides), each having a sensitivity greater than 250 mv/g over a frequency range of 0.1 to 4000 Hz, and processed in a multi-channel Fourier spectrum analyzer with automatic threshold detection. An acoustic transient or energy release processor could conceivably detect the onset of the leak at the moment of fracture of the tank wall. The primary limitations to realizing reliable and robust acoustic emission monitoring of underground fluid leaks are the various masking noise sources prevalent at Air Force bases, which are attributed to aircraft, motor traffic, pump station operation, and ground tremors.

  8. Idaho National Laboratory (INL) Site Greenhouse Gas (GHG) Monitoring Plan - 40 CFR 98

    SciTech Connect

    Deborah L. Layton; Kimberly Frerichs

    2010-07-01

    The purpose of this Greenhouse Gas (GHG) Monitoring Plan is to meet the monitoring plan requirements of Title 40 of the Code of Federal Regulations Part 98.3(g)(5). This GHG Monitoring Plan identifies procedures and methodologies used at the Idaho National Laboratory Site (INL Site) to collect data used for GHG emissions calculations and reporting requirements from stationary combustion and other regulated sources in accordance with 40 CFR 98, Subparts A and other applicable subparts. INL Site Contractors determined subpart applicability through the use of a checklist (Appendix A). Each facility/contractor reviews operations to determine which subparts are applicable and the results are compiled to determine which subparts are applicable to the INL Site. This plan is applicable to the 40 CFR 98-regulated activities managed by the INL Site contractors: Idaho National Laboratory (INL), Idaho Cleanup Project (ICP), Advanced Mixed Waste Treatment Project (AMWTP), and Naval Reactors Facilities (NRF).

  9. Idaho National Laboratory (INL) Site Greenhouse Gas (GHG) Monitoring Plan - 40 CFR 98

    SciTech Connect

    Deborah L. Layton; Kimberly Frerichs

    2011-12-01

    The purpose of this Greenhouse Gas (GHG) Monitoring Plan is to meet the monitoring plan requirements of Title 40 of the Code of Federal Regulations Part 98.3(g)(5). This GHG Monitoring Plan identifies procedures and methodologies used at the Idaho National Laboratory Site (INL Site) to collect data used for GHG emissions calculations and reporting requirements from stationary combustion and other regulated sources in accordance with 40 CFR 98, Subparts A and other applicable subparts. INL Site Contractors determined subpart applicability through the use of a checklist (Appendix A). Each facility/contractor reviews operations to determine which subparts are applicable and the results are compiled to determine which subparts are applicable to the INL Site. This plan is applicable to the 40 CFR 98-regulated activities managed by the INL Site contractors: Idaho National Laboratory (INL), Idaho Cleanup Project (ICP), Advanced Mixed Waste Treatment Project (AMWTP), and Naval Reactors Facilities (NRF).

  10. Air Monitoring: New Advances in Sampling and Detection

    PubMed Central

    Watson, Nicola; Davies, Stephen; Wevill, David

    2011-01-01

    As the harmful effects of low-level exposure to hazardous organic air pollutants become more evident, there is constant pressure to improve the detection limits of indoor and ambient air monitoring methods, for example, by collecting larger air volumes and by optimising the sensitivity of the analytical detector. However, at the other end of the scale, rapid industrialisation in the developing world and growing pressure to reclaim derelict industrial land for house building is driving the need for air monitoring methods that can reliably accommodate very-high-concentration samples in potentially aggressive matrices. This paper investigates the potential of a combination of two powerful gas chromatography—based analytical enhancements—sample preconcentration/thermal desorption and time-of-flight mass spectrometry—to improve quantitative and qualitative measurement of very-low-(ppt) level organic chemicals, even in the most complex air samples. It also describes new, practical monitoring options for addressing equally challenging high-concentration industrial samples. PMID:22241966

  11. A monitor for the laboratory evaluation of control integrity in digital control systems operating in harsh electromagnetic environments

    NASA Technical Reports Server (NTRS)

    Belcastro, Celeste M.; Fischl, Robert; Kam, Moshe

    1992-01-01

    This paper presents a strategy for dynamically monitoring digital controllers in the laboratory for susceptibility to electromagnetic disturbances that compromise control integrity. The integrity of digital control systems operating in harsh electromagnetic environments can be compromised by upsets caused by induced transient electrical signals. Digital system upset is a functional error mode that involves no component damage, can occur simultaneously in all channels of a redundant control computer, and is software dependent. The motivation for this work is the need to develop tools and techniques that can be used in the laboratory to validate and/or certify critical aircraft controllers operating in electromagnetically adverse environments that result from lightning, high-intensity radiated fields (HIRF), and nuclear electromagnetic pulses (NEMP). The detection strategy presented in this paper provides dynamic monitoring of a given control computer for degraded functional integrity resulting from redundancy management errors, control calculation errors, and control correctness/effectiveness errors. In particular, this paper discusses the use of Kalman filtering, data fusion, and statistical decision theory in monitoring a given digital controller for control calculation errors.

  12. Monitoring, mitigation, and verification at sequestration sites: SEQURE technologies and the challenge for geophysical detection

    SciTech Connect

    Wells, A.W.; Hammack, R.W.; Veloski, G.A.; Diehl, J.R.; Strazisar, B.R.; Rauch, H.; Wilson, T.H.; White, C.M.

    2006-10-01

    Editor's note: SEQURE is a trademark of The National Energy Technology Laboratory. A critical component of the National Energy Technology Laboratory's Sequestration Program is the development of tools that can reliably monitor and quantify the amount of CO2 that leaks to the surface. One major requirement for the commercial application of geologic sequestration is accurate leak detection; i.e., leak monitoring and accurate estimation of leak volumes through continued monitoring. This is essential to assure that long-term sequestration is achieved. Significant leakage from the sequestration reservoir defeats the purpose of sequestration, which is to stabilize and then reduce atmospheric concentrations of CO2 for several hundreds to thousands of years. Multiple investigators have attempted to estimate the amount of leakage that is acceptable (e.g., Pacala, 2002; Hepple and Benson, 2002; Dooley and Wise, 2002; Herzog, 2002). Their estimates vary considerably, and range from 1% to 0.01% per annum which leads to leakage of 50% of the injected CO2 volume in 70 to 7000 years, respectively.

  13. Monitoring of Hadrontherapy Treatments by Means of Charged Particle Detection.

    PubMed

    Muraro, Silvia; Battistoni, Giuseppe; Collamati, Francesco; De Lucia, Erika; Faccini, Riccardo; Ferroni, Fernando; Fiore, Salvatore; Frallicciardi, Paola; Marafini, Michela; Mattei, Ilaria; Morganti, Silvio; Paramatti, Riccardo; Piersanti, Luca; Pinci, Davide; Rucinski, Antoni; Russomando, Andrea; Sarti, Alessio; Sciubba, Adalberto; Solfaroli-Camillocci, Elena; Toppi, Marco; Traini, Giacomo; Voena, Cecilia; Patera, Vincenzo

    2016-01-01

    The interaction of the incoming beam radiation with the patient body in hadrontherapy treatments produces secondary charged and neutral particles, whose detection can be used for monitoring purposes and to perform an on-line check of beam particle range. In the context of ion-therapy with active scanning, charged particles are potentially attractive since they can be easily tracked with a high efficiency, in presence of a relatively low background contamination. In order to verify the possibility of exploiting this approach for in-beam monitoring in ion-therapy, and to guide the design of specific detectors, both simulations and experimental tests are being performed with ion beams impinging on simple homogeneous tissue-like targets (PMMA). From these studies, a resolution of the order of few millimeters on the single track has been proven to be sufficient to exploit charged particle tracking for monitoring purposes, preserving the precision achievable on longitudinal shape. The results obtained so far show that the measurement of charged particles can be successfully implemented in a technology capable of monitoring both the dose profile and the position of the Bragg peak inside the target and finally lead to the design of a novel profile detector. Crucial aspects to be considered are the detector positioning, to be optimized in order to maximize the available statistics, and the capability of accounting for the multiple scattering interactions undergone by the charged fragments along their exit path from the patient body. The experimental results collected up to now are also valuable for the validation of Monte Carlo simulation software tools and their implementation in Treatment Planning Software packages. PMID:27536555

  14. Monitoring of Hadrontherapy Treatments by Means of Charged Particle Detection

    PubMed Central

    Muraro, Silvia; Battistoni, Giuseppe; Collamati, Francesco; De Lucia, Erika; Faccini, Riccardo; Ferroni, Fernando; Fiore, Salvatore; Frallicciardi, Paola; Marafini, Michela; Mattei, Ilaria; Morganti, Silvio; Paramatti, Riccardo; Piersanti, Luca; Pinci, Davide; Rucinski, Antoni; Russomando, Andrea; Sarti, Alessio; Sciubba, Adalberto; Solfaroli-Camillocci, Elena; Toppi, Marco; Traini, Giacomo; Voena, Cecilia; Patera, Vincenzo

    2016-01-01

    The interaction of the incoming beam radiation with the patient body in hadrontherapy treatments produces secondary charged and neutral particles, whose detection can be used for monitoring purposes and to perform an on-line check of beam particle range. In the context of ion-therapy with active scanning, charged particles are potentially attractive since they can be easily tracked with a high efficiency, in presence of a relatively low background contamination. In order to verify the possibility of exploiting this approach for in-beam monitoring in ion-therapy, and to guide the design of specific detectors, both simulations and experimental tests are being performed with ion beams impinging on simple homogeneous tissue-like targets (PMMA). From these studies, a resolution of the order of few millimeters on the single track has been proven to be sufficient to exploit charged particle tracking for monitoring purposes, preserving the precision achievable on longitudinal shape. The results obtained so far show that the measurement of charged particles can be successfully implemented in a technology capable of monitoring both the dose profile and the position of the Bragg peak inside the target and finally lead to the design of a novel profile detector. Crucial aspects to be considered are the detector positioning, to be optimized in order to maximize the available statistics, and the capability of accounting for the multiple scattering interactions undergone by the charged fragments along their exit path from the patient body. The experimental results collected up to now are also valuable for the validation of Monte Carlo simulation software tools and their implementation in Treatment Planning Software packages. PMID:27536555

  15. 1997 LMITCO Environmental Monitoring Program Report for the Idaho National Engineering and Environmental Laboratory

    SciTech Connect

    Andersen, B.; Street, L.; Wilhelmsen, R.

    1998-09-01

    This report describes the calendar year 1997 environmental surveillance and compliance monitoring activities of the Lockheed Martin Idaho Technologies Company Environmental Monitoring Program performed at the Idaho National Engineering and Environmental Laboratory. This report includes results of sampling performed by the Radiological Environmental Surveillance, Site Environmental Surveillance, Drinking Water, Effluent Monitoring, Storm Water Monitoring, Groundwater Monitoring, and Special Request Monitoring Programs and compares 1997 data with program-specific regulatory guidelines and past data to evaluate trends. The primary purposes of the surveillance and monitoring activities are to evaluate environmental conditions, to provide and interpret data, to verify compliance with applicable regulations or standard, and to ensure protection of human health and the environment. Surveillance of environmental media did not identify any previously unknown environmental problems or trends indicating a loss of control or unplanned releases from facility operations. With the exception of one nitrogen sample in the disposal pond effluent stream and iron and total coliform bacteria in groundwater downgradient from one disposal pond, compliance with permits and applicable regulations was achieved. Data collected by the Environmental Monitoring Program demonstrate that public health and the environment were protected.

  16. Use of the UNCLE Facility to Assess Integrated Online Monitoring Systems for Detection of Diversions at Uranium Conversion Facilities

    SciTech Connect

    Dewji, Shaheen A; Chapman, Jeffrey Allen; Lee, Denise L; Rauch, Eric; Hertel, Nolan

    2011-01-01

    Historically, the approach to safeguarding nuclear material in the front end of the fuel cycle was implemented only at the stage when UF6 was declared as feedstock for enrichment plants. Recent International Atomic Energy Agency (IAEA) circulars and policy papers have sought to implement safeguards when any purified aqueous uranium solution or uranium oxides suitable for isotopic enrichment or fuel fabrication exist. Oak Ridge National Laboratory has developed the Uranyl Nitrate Calibration Loop Equipment (UNCLE) facility to simulate the full-scale operating conditions for a purified uranium-bearing aqueous stream exiting the solvent extraction process conducted in a natural uranium conversion plant (NUCP) operating at 6000 MTU/year. Monitoring instruments, including the 3He passive neutron detector developed at Los Alamos National Laboratory and the Endress+Hauser Promass 83F Coriolis meter, have been tested at UNCLE and field tested at Springfields. The field trials demonstrated the need to perform full-scale equipment testing under controlled conditions prior to field deployment of operations and safeguards monitoring at additional plants. Currently, UNCLE is testing neutron-based monitoring for detection of noncompliant activities; however, gamma-ray source term monitoring is currently being explored complementary to the neutron detector in order to detect undeclared activities in a more timely manner. The preliminary results of gamma-ray source term modeling and monitoring at UNCLE are being analyzed as part of a comprehensive source term and detector benchmarking effort. Based on neutron source term detection capabilities, alternative gamma-based detection and monitoring methods will be proposed to more effectively monitor NUCP operations in verifying or detecting deviations from declared conversion activities.

  17. Natural Oil Seepages : Detection, Monitoring and Relationships with Submarine Morphologies

    NASA Astrophysics Data System (ADS)

    Dhont, D.; Jatiault, R.; Dubucq, D.; Longépé, N.; Nhunfat, B.; Lucas, M.

    2014-12-01

    Detection of hydrocarbon shows in marine areas is of primary importance for oil and gas exploration since they confirm hydrocarbon generation and prove the presence of an active petroleum system. The use of spaceborne Synthetic Aperture Radar (SAR) images serves as an ideal technology for the imaging of hydrocarbon seeps as it is cost effective, provides large ground coverage with continuous acquisitions and operates day and night and in all weather conditions. Here, we present results on the interpretation of radar images for seepage detection on the West African margin. Long-term monitoring of 150 SAR scenes during 20 years allowed the recognition of more than 1400 oil seepages. Seabed morphologies associated to oil leakage correspond to clusters of small sized pockmarks, 50 to 200 m in diameter, and high-reflectivity mounds. The correlation between the location of the impact point of the oil plume at the sea surface with the seabed features reveals that oceanic drift of the oil is less than 1000 m through a water column of 1800 m, with a rising speed of 10 cm/s. In order to address the question of the seeps lifetime, we set up a short-term monitoring through the acquisition of one radar scene every 12 hours during 10 days in a specific area recognized for active oil leaking. Our main observations are: (i) the number of detected seeps varies spatially and temporally, and (ii) oil seep dissipation is effective in less than 12 hours. The variation of the hydrostatic pressure in the water column associated to the oscillation of the tide has been firstly considered as a possible mechanism controlling the expulsion of oil at the seafloor in relation with the number of seeps detected on each image. However, the correlation between the regional mean wind field and the amount of oil seeps strongly suggests that the wind is a primary factor to be considered for seepage detection. In addition, the age of the seepage on the sea surface is undetermined when the SAR imagery

  18. Use of ArcGIS in Environmental Monitoring at Idaho National Laboratory

    SciTech Connect

    oertel; giles

    2007-06-01

    The Idaho National Laboratory is a U.S. Department of Energy site located in southeastern Idaho. The INL is required to perform environmental monitoring of anthropogenically introduced contaminants. One primary contaminant of interest is radioactive Cs-137 which is resident in INL soils due to past operational activities and atmospheric weapons testing. Collection of field data is performed using vehicle mounted and portable radiation detector units. All data is combined in ArcGIS and displayed over georeferenced satellite images and digital elevation models. The use of the ArcGIS geostatistical analysis package enhances the ability to look for areas of higher Cs-137 concentration. Combining current monitoring results with meteorological wind pattern maps allows for siting of new and improved monitoring locations. Use of the ArcGIS package provides an integrated analysis and mapping protocol for use in radioactive contaminant monitoring.

  19. Above-ground Antineutrino Detection for Nuclear Reactor Monitoring

    SciTech Connect

    Sweany, Melinda; Brennan, James S.; Cabrera-Palmer, Belkis; Kiff, Scott D.; Reyna, David; Throckmorton, Daniel J.

    2014-08-01

    Antineutrino monitoring of nuclear reactors has been demonstrated many times, however the technique has not as of yet been developed into a useful capability for treaty verification purposes. The most notable drawback is the current requirement that detectors be deployed underground, with at least several meters-water-equivalent of shielding from cosmic radiation. In addition, the deployment of liquid-based detector media presents a challenge in reactor facilities. We are currently developing a detector system that has the potential to operate above ground and circumvent deployment problems associated with a liquid detection media: the system is composed of segments of plastic scintillator surrounded by 6LiF/ZnS:Ag. ZnS:Ag is a radio-luminescent phosphor used to detect the neutron capture products of lithium-6. Because of its long decay time compared to standard plastic scintillators, pulse-shape discrimination can be used to distinguish positron and neutron interactions resulting from the inverse beta decay (IBD) of antineutrinos within the detector volume, reducing both accidental and correlated backgrounds. Segmentation further reduces backgrounds by identifying the positron’s annihilation gammas, which are absent for most correlated and uncorrelated backgrounds. This work explores different configurations in order to maximize the size of the detector segments without reducing the intrinsic neutron detection efficiency. We believe this technology will ultimately be applicable to potential safeguards scenarios such as those recently described.

  20. Above-ground Antineutrino Detection for Nuclear Reactor Monitoring

    DOE PAGESBeta

    Sweany, Melinda; Brennan, James S.; Cabrera-Palmer, Belkis; Kiff, Scott D.; Reyna, David; Throckmorton, Daniel J.

    2014-08-01

    Antineutrino monitoring of nuclear reactors has been demonstrated many times, however the technique has not as of yet been developed into a useful capability for treaty verification purposes. The most notable drawback is the current requirement that detectors be deployed underground, with at least several meters-water-equivalent of shielding from cosmic radiation. In addition, the deployment of liquid-based detector media presents a challenge in reactor facilities. We are currently developing a detector system that has the potential to operate above ground and circumvent deployment problems associated with a liquid detection media: the system is composed of segments of plastic scintillator surroundedmore » by 6LiF/ZnS:Ag. ZnS:Ag is a radio-luminescent phosphor used to detect the neutron capture products of lithium-6. Because of its long decay time compared to standard plastic scintillators, pulse-shape discrimination can be used to distinguish positron and neutron interactions resulting from the inverse beta decay (IBD) of antineutrinos within the detector volume, reducing both accidental and correlated backgrounds. Segmentation further reduces backgrounds by identifying the positron’s annihilation gammas, which are absent for most correlated and uncorrelated backgrounds. This work explores different configurations in order to maximize the size of the detector segments without reducing the intrinsic neutron detection efficiency. We believe this technology will ultimately be applicable to potential safeguards scenarios such as those recently described.« less

  1. Medical radar considerations for detecting and monitoring Crohn's disease

    NASA Astrophysics Data System (ADS)

    Smith, Sonny; Narayanan, Ram M.; Messaris, Evangelos

    2014-05-01

    Crohn's disease is a condition that causes inflammation and associated complications along any section of the digestive tract. Over the years, numerous radiological and endoscopic methods as well as the use of ultrasound have been developed to examine and diagnose inflammatory bowel disorders such as Crohn's disease. While such techniques have much merit, an alternative medical solution that is safe, non-invasive, and inexpensive is proposed in this paper. Reflections from electromagnetic signals transmitted by an ultra-wide band (UWB) radar allow for not only range (or extent) information but also spectral analysis of a given target of interest. Moreover, the radar cross-section (RCS) of an object measures how detectable the electromagnetic return energy of such an object is to the radar. In the preliminary phase of research, we investigate how disparities in the dielectric properties of diseased versus non-diseased portions of the intestines can aid in the detection of Crohn's disease. RCS analysis from finite-difference time-domain (FDTD) method simulations using a simple 3D model of the intestines are presented. The ultimate goal of our research is to design a UWB radar system using a suitable waveform to detect and monitor Crohn's disease.

  2. Quantitative Assessment of Detection Frequency for the INL Ambient Air Monitoring Network

    SciTech Connect

    A. Jeffrey Sondrup; Arthur S. Rood

    2014-11-01

    A quantitative assessment of the Idaho National Laboratory (INL) air monitoring network was performed using frequency of detection as the performance metric. The INL air monitoring network consists of 37 low-volume air samplers in 31 different locations. Twenty of the samplers are located on INL (onsite) and 17 are located off INL (offsite). Detection frequencies were calculated using both BEA and ESER laboratory minimum detectable activity (MDA) levels. The CALPUFF Lagrangian puff dispersion model, coupled with 1 year of meteorological data, was used to calculate time-integrated concentrations at sampler locations for a 1-hour release of unit activity (1 Ci) for every hour of the year. The unit-activity time-integrated concentration (TICu) values were calculated at all samplers for releases from eight INL facilities. The TICu values were then scaled and integrated for a given release quantity and release duration. All facilities modeled a ground-level release emanating either from the center of the facility or at a point where significant emissions are possible. In addition to ground-level releases, three existing stacks at the Advanced Test Reactor Complex, Idaho Nuclear Technology and Engineering Center, and Material and Fuels Complex were also modeled. Meteorological data from the 35 stations comprising the INL Mesonet network, data from the Idaho Falls Regional airport, upper air data from the Boise airport, and three-dimensional gridded data from the weather research forecasting model were used for modeling. Three representative radionuclides identified as key radionuclides in INL’s annual National Emission Standards for Hazardous Air Pollutants evaluations were considered for the frequency of detection analysis: Cs-137 (beta-gamma emitter), Pu-239 (alpha emitter), and Sr-90 (beta emitter). Source-specific release quantities were calculated for each radionuclide, such that the maximum inhalation dose at any publicly accessible sampler or the National

  3. Structural health monitoring and impact detection for primary aircraft structures

    NASA Astrophysics Data System (ADS)

    Kosters, Eric; van Els, Thomas J.

    2010-04-01

    The increasing use of thermoplastic carbon fiber-reinforced plastic (CFRP) materials in the aerospace industry for primary aircraft structures, such as wing leading-edge surfaces and fuselage sections, has led to rapid growth in the field of structural health monitoring (SHM). Impact, vibration, and load can all cause failure, such as delamination and matrix cracking, in composite materials. Moreover, the internal material damage can occur without being visible to the human eye, making inspection of and clear insight into structural integrity difficult using currently available evaluation methods. Here, we describe the detection of impact and its localization in materials and structures by high-speed interrogation of multiple-fiber Bragg grating (FBG) sensors mounted on a composite aircraft component.

  4. A novel mobile system for radiation detection and monitoring

    NASA Astrophysics Data System (ADS)

    Biafore, Mauro

    2014-05-01

    A novel mobile system for real time, wide area radiation surveillance has been developed within the REWARD project, financed within the FP7 programme, theme SEC-2011.1.5-1 (Development of detection capabilities of difficult to detect radioactive sources and nuclear materials - Capability Project). The REWARD sensing units are small, mobile portable units with low energy consumption, which consist of new miniaturized solid-state radiation sensors: a CdZnTe detector for gamma radiation and a high efficiency neutron detector based on novel silicon technologies. The sensing unit is integrated by a wireless communication interface to send the data remotely to a monitoring base station as well as a GPS system to calculate the position of the tag. The system also incorporates middleware and high-level software to provide web-service interfaces for the exchange of information. A central monitoring and decision support system has been designed to process the data from the sensing units and to compare them with historical record in order to generate an alarm when an abnormal situation is detected. A security framework ensures protection against unauthorized access to the network and data, ensuring the privacy of the communications and contributing to the overall robustness and reliability of the REWARD system. The REWARD system has been designed for many different scenarios such as nuclear terrorism threats, lost radioactive sources, radioactive contamination or nuclear accidents. It can be deployed in emergency units and in general in any type of mobile or static equipment, but also inside public/private buildings or infrastructures. The complete system is scalable in terms of complexity and cost and offers very high precision on both the measurement and the location of the radiation. The modularity and flexibility of the system allows for a realistic introduction to the market. Authorities may start with a basic, low cost system and increase the complexity based on their

  5. Above-ground antineutrino detection for nuclear reactor monitoring

    NASA Astrophysics Data System (ADS)

    Sweany, M.; Brennan, J.; Cabrera-Palmer, B.; Kiff, S.; Reyna, D.; Throckmorton, D.

    2015-01-01

    Antineutrino monitoring of nuclear reactors has been demonstrated many times (Klimov et al., 1994 [1]; Bowden et al., 2009 [2]; Oguri et al., 2014 [3]), however the technique has not as of yet been developed into a useful capability for treaty verification purposes. The most notable drawback is the current requirement that detectors be deployed underground, with at least several meters-water-equivalent of shielding from cosmic radiation. In addition, the deployment of liquid-based detection media presents a challenge in reactor facilities. We are currently developing a detector system that has the potential to operate above ground and circumvent deployment problems associated with a liquid detection media: the system is composed of segments of plastic scintillator surrounded by 6LiF/ZnS:Ag. ZnS:Ag is a radio-luminescent phosphor used to detect the neutron capture products of 6Li. Because of its long decay time compared to standard plastic scintillators, pulse-shape discrimination can be used to distinguish positron and neutron interactions resulting from the inverse beta decay (IBD) of antineutrinos within the detector volume, reducing both accidental and correlated backgrounds. Segmentation further reduces backgrounds by identifying the positron's annihilation gammas, a signature that is absent for most correlated and uncorrelated backgrounds. This work explores different configurations in order to maximize the size of the detector segments without reducing the intrinsic neutron detection efficiency. We believe that this technology will ultimately be applicable to potential safeguards scenarios such as those recently described by Huber et al. (2014) [4,5].

  6. Metallurgical Laboratory Hazardous Waste Management Facility groundwater monitoring report. Second quarter 1993

    SciTech Connect

    Thompson, C.Y.

    1993-09-01

    During second quarter 1993, samples from AMB groundwater monitoring wells at the metallurgical Laboratory Hazardous Waste Management Facility (HWMF) were analyzed for certain heavy metals, indicator parameters, radionuclides, volatile organic compounds, and other constituents. Six parameters exceeded standards during the quarter. As in previous quarters, tetrachloroethylene and trichloroethylene exceeded final Primary Drinking Water Standards (PDWS), and pH and total organic halogens exceeded the Savannah River Site (SRS) Flag 2 criteria in one or more of the wells. Dichloromethane (methylene chloride), a common laboratory contaminant which was first compared to its final PDWS during first quarter 1993, was elevated in three wells.

  7. Field and laboratory studies of Fourier transform infrared spectroscopy in continuous emissions monitoring applications

    NASA Astrophysics Data System (ADS)

    Plummer, Grant M.

    1991-04-01

    Entropy Environmentalists, Inc. has performed a number of field and laboratory studies using a FTIR spectrometer for the analysis of gas phase samples and sample streams. The field studies, undertaken in conjunction with the U.S. Environmental Protection Agency (EPA), included several weeks of continuous monitoring at a hazardous waste incinerator, a sewage sludge incinerator, and a coal-fired boiler. Results of the analyses of both cold and hot samples, using several types of infrared absorption cells, will be discussed and compared to the results of other continuous monitoring systems.

  8. Adapting Raman spectra from laboratory spectrometers to portable detection libraries.

    PubMed

    Weatherall, James C; Barber, Jeffrey; Brauer, Carolyn S; Johnson, Timothy J; Su, Yin-Fong; Ball, Christopher D; Smith, Barry T; Cox, Rick; Steinke, Robert; McDaniel, Patricia; Wasserzug, Louis

    2013-02-01

    Raman spectral data collected with high-resolution laboratory spectrometers are processed into a format suitable for importing as a user library on a 1064 nm DeltaNu first generation, field-deployable spectrometer prototype. The two laboratory systems used are a 1064 nm Bruker Fourier transform (FT)-Raman spectrometer and a 785 nm Kaiser dispersive spectrometer. The steps taken to adapt for device-dependent spectral resolution, wavenumber shifts between instruments, and relative intensity response are described. Effects due to the differing excitation laser wavelengths were found to be minimal, indicating--at least for the near-infrared (NIR)--that data can be ported between different systems, so long as certain measures are taken with regard to the reference and field spectra. PMID:23622433

  9. Electrical Resistance Technique to Monitor SiC Composite Detection

    NASA Technical Reports Server (NTRS)

    Smith, Craig; Morscher, Gregory; Xia, Zhenhai

    2008-01-01

    Ceramic matrix composites are suitable for high temperature structural applications such as turbine airfoils and hypersonic thermal protection systems. The employment of these materials in such applications is limited by the ability to process components reliable and to accurately monitor and predict damage evolution that leads to failure under stressed-oxidation conditions. Current nondestructive methods such as ultrasound, x-ray, and thermal imaging are limited in their ability to quantify small scale, transverse, in-plane, matrix cracks developed over long-time creep and fatigue conditions. Electrical resistance of SiC/SiC composites is one technique that shows special promise towards this end. Since both the matrix and the fibers are conductive, changes in matrix or fiber properties should relate to changes in electrical conductivity along the length of a specimen or part. The effect of matrix cracking on electrical resistivity for several composite systems will be presented and some initial measurements performed at elevated temperatures under stress-rupture conditions. The implications towards electrical resistance as a technique applied to composite processing, damage detection (health monitoring), and life-modeling will be discussed.

  10. Hierarchical effects on target detection and conflict monitoring

    PubMed Central

    Cao, Bihua; Gao, Feng; Ren, Maofang; Li, Fuhong

    2016-01-01

    Previous neuroimaging studies have demonstrated a hierarchical functional structure of the frontal cortices of the human brain, but the temporal course and the electrophysiological signature of the hierarchical representation remains unaddressed. In the present study, twenty-one volunteers were asked to perform a nested cue-target task, while their scalp potentials were recorded. The results showed that: (1) in comparison with the lower-level hierarchical targets, the higher-level targets elicited a larger N2 component (220–350 ms) at the frontal sites, and a smaller P3 component (350–500 ms) across the frontal and parietal sites; (2) conflict-related negativity (non-target minus target) was greater for the lower-level hierarchy than the higher-level, reflecting a more intensive process of conflict monitoring at the final step of target detection. These results imply that decision making, context updating, and conflict monitoring differ among different hierarchical levels of abstraction. PMID:27561989

  11. Hierarchical effects on target detection and conflict monitoring.

    PubMed

    Cao, Bihua; Gao, Feng; Ren, Maofang; Li, Fuhong

    2016-01-01

    Previous neuroimaging studies have demonstrated a hierarchical functional structure of the frontal cortices of the human brain, but the temporal course and the electrophysiological signature of the hierarchical representation remains unaddressed. In the present study, twenty-one volunteers were asked to perform a nested cue-target task, while their scalp potentials were recorded. The results showed that: (1) in comparison with the lower-level hierarchical targets, the higher-level targets elicited a larger N2 component (220-350 ms) at the frontal sites, and a smaller P3 component (350-500 ms) across the frontal and parietal sites; (2) conflict-related negativity (non-target minus target) was greater for the lower-level hierarchy than the higher-level, reflecting a more intensive process of conflict monitoring at the final step of target detection. These results imply that decision making, context updating, and conflict monitoring differ among different hierarchical levels of abstraction. PMID:27561989

  12. Gas detection and migration in geological media: lessons learned from the Roselend Natural Laboratory (Invited)

    NASA Astrophysics Data System (ADS)

    Pili, E.; Guillon, S.; Agrinier, P.; Sabroux, J.; Adler, P. M.

    2013-12-01

    The Roselend Natural Laboratory (French Alps) is a unique facility for studying gas transport in the subsurface and across the geosphere-atmosphere interface. At 55 m depth, a sealed cavity allows for gas release experiments across fractured porous rocks in the unsaturated zone. While many parameters controlling the state of the geological system are known, analogous gas-tracer experiments were conducted at the field-scale with SF6 and 3He. Water infiltration, permeability and the concentrations of many gases, naturally occurring or injected, are recorded via long-term and high-resolution monitoring. The fracture network is characterized thanks to extensive drilling, logging and modeling. These experiments are used to determine the physical and chemical processes that would control the noble gas source term after an underground nuclear explosion in the framework of the Comprehensive nuclear-Test-Ban Treaty (CTBT) and to develop and validate the corresponding numerical models. The Roselend Natural Laboratory also provides a test bed for sampling protocols and instrument developments. Detection of gases relevant to CTBT issues requires that their baseline concentration is understood. Experiments and subsequent modeling demonstrated that baselines are a highly dynamical process resulting from gas sources, sinks and modulation by barometric pressure and water movements. Gas migration from underground cavities occurs as early venting through fractures due to advection driven by gas overpressure. It is associated with very large dilution which requires very low detection limits. Late-time seepage occurs through fractured porous media thanks to barometric pumping, which is only efficient for a narrow window of parameter values. Full calculation for real fractured porous media is now available.

  13. Acoustic Methods to Monitor Protein Crystallization and to Detect Protein Crystals in Suspensions of Agarose and Lipidic Cubic Phase.

    PubMed

    Ericson, Daniel L; Yin, Xingyu; Scalia, Alexander; Samara, Yasmin N; Stearns, Richard; Vlahos, Harry; Ellson, Richard; Sweet, Robert M; Soares, Alexei S

    2016-02-01

    Improvements needed for automated crystallography include crystal detection and crystal harvesting. A technique that uses acoustic droplet ejection to harvest crystals was previously reported. Here a method is described for using the same acoustic instrument to detect protein crystals and to monitor crystal growth. Acoustic pulses were used to monitor the progress of crystallization trials and to detect the presence and location of protein crystals. Crystals were detected, and crystallization was monitored in aqueous solutions and in lipidic cubic phase. Using a commercially available acoustic instrument, crystals measuring ~150 µm or larger were readily detected. Simple laboratory techniques were used to increase the sensitivity to 50 µm by suspending the crystals away from the plastic surface of the crystallization plate. This increased the sensitivity by separating the strong signal generated by the plate bottom that can mask the signal from small protein crystals. It is possible to further boost the acoustic reflection from small crystals by reducing the wavelength of the incident sound pulse, but our current instrumentation does not allow this option. In the future, commercially available sound-emitting transducers with a characteristic frequency near 300 MHz should detect and monitor the growth of individual 3 µm crystals. PMID:26574563

  14. Misuse and intrusion detection at Los Alamos National Laboratory

    SciTech Connect

    Jackson, K.A.; Neuman, M.C.; Simmonds, D.D.; Stallings, C.A.; Thompson, J.L.; Christoph, G.G.

    1995-04-01

    An effective method for detecting computer misuse is the automatic auditing and analysis of on-line user activity. This activity is reflected in system audit records, in system vulnerability postures, and in other evidence found through active system testing. Since 1989 we have implemented a misuse and intrusion detection system at Los Alamos. This is the Network Anomaly Detection and Intrusion Reporter, or NADIR. NADIR currently audits a Kerberos distributed authentication system, file activity on a mass, storage system, and four Cray supercomputers that run the UNICOS operating system. NADIR summarizes user activity and system configuration in statistical profiles. It compares these profiles to expert rules that define security policy and improper or suspicious behavior. It reports suspicious behavior to security auditors and provides tools to aid in follow-up investigations, As NADIR is constantly evolving, this paper reports its development to date.

  15. Measurement of biomarker proteins for point-of-care early detection and monitoring of cancer

    PubMed Central

    Kumar, Challa V.; Gutkind, J. Silvio; Patel, Vyomesh

    2010-01-01

    This critical review evaluates progress toward viable point-of-care protein biomarker measurements for cancer detection and diagnostics. The ability to measure panels of specific, selective cancer biomarker proteins in physicians’ surgeries and clinics has the potential to revolutionize cancer detection, monitoring, and therapy. The dream envisions reliable, cheap, automated, technically undemanding devices that can analyze a patient’s serum or saliva in a clinical setting, allowing on-the-spot diagnosis. Existing commercial products for protein assays are reliable in laboratory settings, but have limitations for point-of-care applications. A number of ultrasensitive immunosensors and some arrays have been developed, many based on nanotechnology. Multilabel detection coupled with high capture molecule density in immunosensors and arrays seems to be capable of detecting a wide range of protein concentrations with sensitivity ranging into the sub pg mL−1 level. Multilabel arrays can be designed to detect both high and ultralow abundance proteins in the same sample. However, only a few of the newer ultrasensitive methods have been evaluated with real patient samples, which is key to establishing clinical sensitivity and selectivity. PMID:20614087

  16. Runway Safety Monitor Algorithm for Runway Incursion Detection and Alerting

    NASA Technical Reports Server (NTRS)

    Green, David F., Jr.; Jones, Denise R. (Technical Monitor)

    2002-01-01

    The Runway Safety Monitor (RSM) is an algorithm for runway incursion detection and alerting that was developed in support of NASA's Runway Incursion Prevention System (RIPS) research conducted under the NASA Aviation Safety Program's Synthetic Vision System element. The RSM algorithm provides pilots with enhanced situational awareness and warnings of runway incursions in sufficient time to take evasive action and avoid accidents during landings, takeoffs, or taxiing on the runway. The RSM currently runs as a component of the NASA Integrated Display System, an experimental avionics software system for terminal area and surface operations. However, the RSM algorithm can be implemented as a separate program to run on any aircraft with traffic data link capability. The report documents the RSM software and describes in detail how RSM performs runway incursion detection and alerting functions for NASA RIPS. The report also describes the RIPS flight tests conducted at the Dallas-Ft Worth International Airport (DFW) during September and October of 2000, and the RSM performance results and lessons learned from those flight tests.

  17. Metallurgical Laboratory Hazardous Waste Management Facility groundwater monitoring report, Third quarter 1992

    SciTech Connect

    Not Available

    1992-12-01

    During third quarter 1992, samples from 18 groundwater monitoring wells of the AMB series at the Metallurgical Laboratory Hazardous Waste Management Facility were analyzed for certain heavy metals, indicator parameters, radionuclides, volatile organic compounds, and other constituents. Eight parameters exceeded the US Environmental Protection Agency Primary Drinking Water Standards (PDWS) and the Savannah River Site Flag 2 criteria during the quarter. This report details the groundwater sampling activities for third quarter 1992.

  18. Metallurgical Laboratory Hazardous Waste Management Facility (HWMF) groundwater monitoring report, second quarter 1992

    SciTech Connect

    Thompson, C.Y.

    1992-09-01

    During second quarter 1992, 18 groundwater monitoring wells of the AMB series at the Metallurgical Laboratory Hazardous Waste Management Facility (Met Lab HWMF) were visited for sampling. Groundwater samples were analyzed for certain heavy metals, indicator parameters, radionuclides, volatile organic compounds, and other constituents. This report describes the results that exceeded the US Environmental Protection Agency Primary Drinking Water Standards (PDWS) and the Savannah River Site flagging criteria during the quarter.

  19. Lawrence Livermore National Laboratory?s Book of Minimum Detectable Activity for Direct Measurement of Internally Deposited Radionuclides in Radiation Workers

    SciTech Connect

    Hickman, D P

    2008-10-08

    Lawrence Livermore National Laboratory maintains an in vivo measurement program designed to identify and evaluate the activity of radionuclides deposited in the body. Two types of systems are primarily used for the routine monitoring of radiation workers, the lung counting system and the scanning bed whole body counting system. The lung counting system is comprised of two Canberra ACTII detector sets. Each ACTII set contains two planar germanium detectors with carbon composite end windows optimized to measure low energy photon emitting radionuclides. The ACTII detectors are placed on the upper torso over the lungs for the direct measurement of internally deposited radionuclides in the lungs that emit low energy photons. A correction for the thickness of the chest wall is applied to the efficiency. Because the thickness of the chest wall is a key factor in the measurement of low energy photon emitting radionuclides in the lung, the minimum detectable activity is a function of the chest wall thickness. The scanning bed whole body counting system is comprised of a thin air mattress on top of a carbon fiber bed that slowly scans over four high purity germanium detectors. The scanning system is designed to minimize variations in detected activity due to radionuclide distribution in the body. The scanning bed detection system is typically used for the measurement of internally deposited radionuclides that emit photons above 100 to 200 keV. MDAs have been generated for radionuclides that provide energies above 80 keV since the lowest calibration energy for the system is approximately 86 keV. The following charts and table provide best determination of minimum detectable activity using human subjects as controls for the background contributions. A wide variety of radionuclides are used throughout the laboratory and the following pages represent several of the radionuclides that have been encountered at the Whole Body and Spectroscopy Laboratories within Hazards Control.

  20. Nonradioactive Ambient Air Monitoring at Los Alamos National Laboratory 2001--2002

    SciTech Connect

    E. Gladney; J.Dewart, C.Eberhart; J.Lochamy

    2004-09-01

    During the spring of 2000, the Cerro Grande forest fire reached Los Alamos National Laboratory (LANL) and ignited both above-ground vegetation and disposed materials in several landfills. During and after the fire, there was concern about the potential human health impacts from chemicals emitted by the combustion of these Laboratory materials. Consequently, short-term, intensive air-monitoring studies were performed during and shortly after the fire. Unlike the radiological data from many years of AIRNET sampling, LANL did not have an adequate database of nonradiological species under baseline conditions with which to compare data collected during the fire. Therefore, during 2001 the Meteorology and Air Quality Group designed and implemented a new air-monitoring program, entitled NonRadNET, to provide nonradiological background data under normal conditions. The objectives of NonRadNET were to: (1) develop the capability for collecting nonradiological air-monitoring data, (2) conduct monitoring to develop a database of typical background levels of selected nonradiological species in the communities nearest the Laboratory, and (3) determine LANL's potential contribution to nonradiological air pollution in the surrounding communities. NonRadNET ended in late December 2002 with five quarters of data. The purpose of this paper is to organize and describe the NonRadNET data collected over 2001-2002 to use as baseline data, either for monitoring during a fire, some other abnormal event, or routine use. To achieve that purpose, in this paper we will: (1) document the NonRadNET program procedures, methods, and quality management, (2) describe the usual origins and uses of the species measured, (3) compare the species measured to LANL and other area emissions, (4) present the five quarters of data, (5) compare the data to known typical environmental values, and (6) evaluate the data against exposure standards.

  1. LABORATORY DETECTION OF PLASTICS IN SEEDCOTTON WITH ION MOBILITY SPECTROMETRY

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The US cotton industry wants to increase market share and value by supplying pure cotton. Removing contamination requires developing a means to detect plastics in seedcotton. This study was conducted to determine if Ion Mobility Spectrometry (IMS) could be used to find small amounts of plastic in ...

  2. Environmental monitoring programs vs Good Laboratory Practice (GLP) programs: differences and similarities.

    PubMed

    Bentley, R E

    1995-12-01

    Environmental monitoring and Good Laboratory Practice programs are similar when looked at empirically. Both address quality issues, human or environmental safety, and have set procedures to assure the concomitant results. However, when compared at the operational level, they can be best described as very different. Good Laboratory Practice programs deal basically with two governmental agencies and their divisions- the Environmental Protection Agency and Food and Drug Administration. These are administered from the federal level involving no state resources. These programs are objective driven with the procedures being defined in study plans, protocols, and standard operating procedures. The environmental monitoring testing programs deal with a profusion of federal legislation including CERCLA (also known as CLP), RCRA, CWA, CAA, SDWA, NPDES and others. These acts require analysis by specific procedures mandated by the statutes. States operate many of these programs and have been given the authority by the federal government. Many of the states require separate certifications to conduct these analyses. Environmental monitoring testing laboratories often must acquire multiple state certifications to participate in multiple state programs. This is not cost effective and often leads to conflicting requirements. Much of the direction for having a national certification program comes from problems associated with these state-operated programs. PMID:8890354

  3. Test plan for preparing the Rapid Transuranic Monitoring Laboratory for field deployment

    SciTech Connect

    McIsaac, C.V.; Sill, C.W.; Gehrke, R.J.; Killian, E.W.; Watts, K.D.

    1994-04-01

    This plan describes experimental work that will be performed during fiscal year 1994 to prepare the Rapid Transuranic Monitoring Laboratory (RTML) for routine field use by US Department of Energy (DOE) Environmental Restoration and Waste Management programs. The RTML is a mobile, field-deployable laboratory developed at the Idaho National Engineering Laboratory (INEL) that provides a rapid, cost-effective means of characterizing and monitoring radioactive waste remediation sites for low-level radioactive contaminants. Analytical instruments currently installed in the RTML include an extended-range, germanium photon analysis spectrometer with an automatic sample changer; two, large-area, ionization chamber alpha spectrometers; and four alpha continuous air monitors. The RTML was field tested at the INEL during June 1993 in conjunction with the Buried Waste Integrated Demonstration`s remote retrieval demonstration. The major tasks described in this test plan are to (a) evaluate the beta detectors for use in screening soil samples for {sup 90}Sr, (b) upgrade the alpha spectral analysis software programs, and (c) upgrade the photon spectral analysis software programs.

  4. Sandia National Laboratories, California Quality Assurance Project Plan for Environmental Monitoring Program.

    SciTech Connect

    Holland, Robert C.

    2005-09-01

    This Quality Assurance Project Plan (QAPP) applies to the Environmental Monitoring Program at the Sandia National Laboratories/California. This QAPP follows DOE Quality Assurance Management System Guide for Use with 10 CFR 830 Subpart A, Quality Assurance Requirements, and DOE O 414.1C, Quality Assurance (DOE G 414.1-2A June 17, 2005). The Environmental Monitoring Program is located within the Environmental Operations Department. The Environmental Operations Department is responsible for ensuring that SNL/CA operations have minimal impact on the environment. The Department provides guidance to line organizations to help them comply with applicable environmental regulations and DOE orders. To fulfill its mission, the department has groups responsible for waste management; pollution prevention, air quality; environmental planning; hazardous materials management; and environmental monitoring. The Environmental Monitoring Program is responsible for ensuring that SNL/CA complies with all Federal, State, and local regulations and with DOE orders regarding the quality of wastewater and stormwater discharges. The Program monitors these discharges both visually and through effluent sampling. The Program ensures that activities at the SNL/CA site do not negatively impact the quality of surface waters in the vicinity, or those of the San Francisco Bay. The Program verifies that wastewater and stormwater discharges are in compliance with established standards and requirements. The Program is also responsible for compliance with groundwater monitoring, and underground and above ground storage tanks regulatory compliance. The Program prepares numerous reports, plans, permit applications, and other documents that demonstrate compliance.

  5. Environmental monitoring plan for Waste Area Grouping 6 at Oak Ridge National Laboratory, Oak Ridge, Tennessee

    SciTech Connect

    1995-09-01

    This document presents an Environmental Monitoring Plan (EMP) for Waste Area Grouping (WAG 6) at Oak Ridge National Laboratory (ORNL). This document updates a draft monitoring plan developed in 1993. The draft plan was never finalized awaiting resolution of the mechanisms for addressing RCRA concerns at a site where the CERCLA process resulted in a decision to defer action, i.e., postpone closure indefinitely. Over the past two years the Tennessee Department of Environment and Conservation (TDEC), US Department of Energy (DOE), and US Environmental Protection Agency (EPA) Region IV, have agreed that RCRA authority at the site will be maintained through a post- closure permit; ``closure`` in this case referring to deferred action. Both a Revised Closure Plan (DOE 1995a) and a Post-Closure Permit Application (DOE 1995b) have been developed to document this agreement; relevant portions of the EMP will be included in the RCRA Post-Closure Permit Application. As the RCRA issues were being negotiated, DOE initiated monitoring at WAG 6. The purpose of the monitoring activities was to (1) continue to comply with RCRA groundwater quality assessment requirements, (2) install new monitoring equipment, and (3) establish the baseline conditions at WAG 6 against which changes in contaminant releases could be measured. Baseline monitoring is scheduled to end September 30, 1995. Activities that have taken place over the past two years are summarized in this document.

  6. Long distance high power optical laser fiber break detection and continuity monitoring systems and methods

    DOEpatents

    Rinzler, Charles C.; Gray, William C.; Faircloth, Brian O.; Zediker, Mark S.

    2016-02-23

    A monitoring and detection system for use on high power laser systems, long distance high power laser systems and tools for performing high power laser operations. In particular, the monitoring and detection systems provide break detection and continuity protection for performing high power laser operations on, and in, remote and difficult to access locations.

  7. Metallurgical Laboratory Hazardous Waste Management Facility groundwater monitoring report. Fourth quarter 1993 and 1993 summary

    SciTech Connect

    Not Available

    1994-03-01

    The AMB wells at the Metallurgical Laboratory Hazardous Waste Management Facility (Met Lab HWMF) are monitored for selected constituents to comply with the Natural Resources Defense council et al. Consent Decree of May 1988 that identifies the Met Lab HWMF as subject to the Resource Conservation and Recovery Act. In addition, the wells are monitored, as requested, for other constituents as part of the Savannah River Site (SRS) Groundwater Monitoring Program. During the fourth quarter 1993, samples from AMB groundwater monitoring wells at the Metallurgical Laboratory Hazardous Waste Management Facility were analyzed for selected heavy metals, indicator parameters, radionuclides, volatile organic compounds, and other constituents. Six parameters exceeded standards during the quarter. As in previous quarters, dichloromethane (methylene chloride), tetrachloroethylene, and trichloroethylene exceeded final Primary Drinking Water Standards; pH, specific conductance, and total organic halogens exceeded the Savannah River Site Flag 2 criteria in one or more of the wells. Groundwater flow direction and rate in the water-table unit were similar to previous quarters.

  8. Rocketdyne division environmental monitoring annual report, Santa Susana Field Laboratory, De Soto, and Canoga Sites, 1990

    SciTech Connect

    none,

    1991-06-20

    This annual report discuses environmental monitoring at three manufacturing and test operations sites operated in the Southern California area by the Rocketdyne Division of Rockwell International Corporation. These are identified as the Santa Susana Field Laboratory (SSFL.), the De Soto site, and the Canoga site. These sites have been used for manufacturing, R&D, engineering, and testing in a broad range of technical fields, primarily rocket engine propulsion and nuclear reactor technology. The De Soto and Canoga sites are essentially light industry with some laboratory-scale R&D and have little potential impact on the environment. The SSFL site, because of its large size (2,668 acres), warranted comprehensive monitoring to assure protection of the environment. The purpose of this report is to present information on environmental and effluent monitoring primarily for the regulatory agencies involved in controlling operations with nuclear and radioactive materials, i.e., the U.S. DOE, the U.S. Nuclear Regulatory Commission (NRC), and the California State Department of Health Services (DHS), Radiologic Health Branch (RHB). For that reason, information concentrates on Area IV at SSFL as this is the site of the former nuclear operations. While the major realm of interest is radiological, this report also includes some discussion of nonradiological monitoring at SSFL

  9. Facility Effluent Monitoring Plan for Pacific Northwest National Laboratory Balance-of-Plant Facilities

    SciTech Connect

    Ballinger, Marcel Y.; Gervais, Todd L.

    2004-11-15

    The Pacific Northwest National Laboratory (PNNL) operates a number of Research & Development (R&D) facilities for the U.S. Department of Energy (DOE) on the Hanford Site. Facility effluent monitoring plans (FEMPs) have been developed to document the facility effluent monitoring portion of the Environmental Monitoring Plan (DOE 2000) for the Hanford Site. Three of PNNL’s R&D facilities, the 325, 331, and 3720 Buildings, are considered major emission points for radionuclide air sampling, and individual FEMPs were developed for these facilities in the past. In addition, a balance-of-plant (BOP) FEMP was developed for all other DOE-owned, PNNL-operated facilities at the Hanford Site. Recent changes, including shutdown of buildings and transition of PNNL facilities to the Office of Science, have resulted in retiring the 3720 FEMP and combining the 331 FEMP into the BOP FEMP. This version of the BOP FEMP addresses all DOE-owned, PNNL-operated facilities at the Hanford Site, excepting the Radiochemical Processing Laboratory, which has its own FEMP because of the unique nature of the building and operations. Activities in the BOP facilities range from administrative to laboratory and pilot-scale R&D. R&D activities include both radioactive and chemical waste characterization, fluid dynamics research, mechanical property testing, dosimetry research, and molecular sciences. The mission and activities for individual buildings are described in Appendix A. Potential radioactive airborne emissions in the BOP facilities are estimated annually using a building inventory-based approach provided in federal regulations. Sampling at individual BOP facilities is based on a potential-to-emit assessment. Some of these facilities are considered minor emission points and thus are sampled routinely, but not continuously, to confirm the low emission potential. One facility, the 331 Life Sciences Laboratory, has a major emission point and is sampled continuously. Sampling systems are

  10. Detection and monitoring of CWA and BWA using LIBS

    NASA Astrophysics Data System (ADS)

    Landström, L.; Larsson, A.; Gradmark, P.-Å.; Örebrand, Lillermor; Andersson, P. O.; Wästerby, Pär.; Tjärnhage, Torbjörn

    2014-05-01

    Results related to laser induced breakdown spectroscopy (LIBS) as an analytical tool for applications regarding CWA and BWA detection/monitoring will be presented and discussed in this paper. A `real-time' aerosol analysis set-up using LIBS on single μm-sized particles (sampled from ambient air into a particle stream) has been developed and evaluated. Here, a two-stage triggering unit ensures a high hit-rate of the sampled aerosol particles and the optical emission from the laser induced plasma is collected and coupled into an echelle spectrometer equipped with an intensified CCD detector. Each CCD image (echellogram), optimally originating from a single μm-sized particle, is then analyzed and the result treated by an alarm algorithm built from a database using multivariate data analysis. The database signatures of simulant agents and interferents were obtained in controlled atmospheres (aerosol chamber/wind tunnel) as well as from measurements in different ambient background. The LIBS bioaerosol system with alarm algorithm was also tested in `real-life' settings (subway station) during simulant dispersions. Painted surfaces have also been analyzed by LIBS to obtain information about residues of organophosphates on, or within, the paint. Depth analysis has been performed, which illustrated the possibility to monitor diffusion and penetration behavior of neat CWAs and simulant chemicals in the paint layer by following the intensity of phosphorous emission lines in single shot LIBS spectra as function of number of laser pulses. In addition, LIBS analysis was also performed after simple ethanol decontamination procedures, after which P emission lines still could be observed. The possibilities and challenges associated with the different set-ups and applications will be briefly discussed in connection with the presented results.

  11. Fluorescence diffuse tomography for tumor detection and monitoring

    NASA Astrophysics Data System (ADS)

    Balalaeva, Irina V.; Orlova, Anna G.; Shirmanova, Marina V.; Kibraeva, Elena A.; Zagainova, Elena V.; Turchin, Ilya V.

    2007-05-01

    Strong light scattering and absorption limit visualization of the internal structure of biological tissue. Only special tools for turbid media imaging, such as optical diffuse tomography, enable noninvasive investigation of the internal biological tissues, including visualization and intravital monitoring of deep tumors. In this work the preliminary results of fluorescence diffuse tomography (FDT) of small animals are presented. Using of exogenous fluorophores, targeted specifically at tumor cells, and fluorescent proteins expressed endogenously can significantly increase the contrast of obtained images. Fluorescent compounds of different nature, such as sulphonated aluminium phthalocyanine (Photosens), red fluorescing proteins and CdTe/CdSe-core/shell nanocrystals (quantum dots) were applied. The animal was scanned in the transilluminative configuration by low-frequency modulated light (1 kHz) from Nd:YAG laser with second harmonic generation at the wavelength of 532 nm or semiconductor laser at the wavelength of 655 nm. Photosens was injected intravenously into linear mice with metastazing Lewis lung carcinoma in dose 4 mg/kg. Quantum dots (5x10 -11 M) or protein DsRed2 (1-5x10 -6 M) in glass capsules (inner diameter 2-3 mm) were placed inside the esophagus of 7-day-old hairless rats (18-20 g) to simulate marked tumors. Cells of HEK-293 Phoenix line, transitory transfected with Turbo-RFP protein gene, were injected hypodermically to immunodeficient mice. This work demonstrates potential capabilities of FDT method for detection and monitoring of deep fluorescent-labeled tumors in animal models. Strong advantages of fluorescent proteins and quantum dots over the traditional photosensitizer for FDT imaging are shown.

  12. Using EEG To Detect and Monitor Mental Fatigue

    NASA Technical Reports Server (NTRS)

    Montgomery, Leslie; Luna, Bernadette; Trejo, Leonard J.; Montgomery, Richard

    2001-01-01

    This project aims to develop EEG-based methods for detecting and monitoring mental fatigue. Mental fatigue poses a serious risk, even when performance is not apparently degraded. When such fatigue is associated with sustained performance of a single type of cognitive task it may be related to the metabolic energy required for sustained activation of cortical areas specialized for that task. The objective of this study was to adapt EEG to monitor cortical energy over a long period of performance of a cognitive task. Multielectrode event related potentials (ERPs) were collected every 15 minutes in nine subjects who performed a mental arithmetic task (algebraic sum of four randomly generated negative or positive digits). A new problem was presented on a computer screen 0.5 seconds after each response; some subjects endured for as long as three hours. ERPs were transformed to a quantitative measure of scalp electrical field energy. The average energy level at electrode P3 (near the left angular gyrus), 100-300 msec latency, was compared over the series of ERPs. For most subjects, scalp energy density at P3 gradually fell over the period of task performance and dramatically increased just before the subject was unable to continue the task. This neural response can be simulated for individual subjects using, a differential equation model in which it is assumed that the mental arithmetic task requires a commitment of metabolic energy that would otherwise be used for brain activities that are temporarily neglected. Their cumulative neglect eventually requires a reallocation of energy away from the mental arithmetic task.

  13. Proficiency of Clinical Laboratories in Spain in Detecting Vancomycin-Resistant Enterococcus spp.

    PubMed Central

    Alonso-Echanove, Juan; Robles, Belen; Jarvis, William R.

    1999-01-01

    Studies in a variety of U.S. clinical laboratories have demonstrated difficulty in detecting intermediate and low-level vancomycin-resistant enterococci (VRE). The misclassification of “at least intermediate resistant isolates” as vancomycin susceptible may have both clinical implications and a negative impact on measures to control the spread of VRE. No published study has assessed the ability of clinical laboratories in Europe to detect VRE. So, the apparent low prevalence of VRE in European hospitals may be, in part, secondary to the inability of these laboratories to detect all VRE. In an effort to assess European laboratories’ proficiency in detecting VRE, we identified 22 laboratories in Spain and asked them to test four VRE strains and one susceptible enterococcal strain from the Centers for Disease Control and Prevention collection. Each organism was tested by the routine antimicrobial susceptibility testing method used by each laboratory. Overall, VRE were correctly identified in 61 of 88 (69.1%) instances. The accuracy of VRE detection varied with the level of resistance and the antimicrobial susceptibility method. The high-level-resistant strain (Enterococcus faecium; MIC, 512 μg/ml) was accurately detected in 20 of 22 (91.3%) instances, whereas the intermediate-resistant isolate (Enterococcus gallinarum; MIC, 8 μg/ml) was accurately detected in only 11 of 22 (50%) instances. Classification errors occurred in 27 of 88 (30.9%) instances. Misclassification as vancomycin susceptible was the most common error (16 of 27 [59.3%] instances). Our study shows that the participating Spanish laboratories had an overall acceptable proficiency in detecting VRE but that a substantial proportion of VRE isolates with low or intermediate levels of resistance were not detected. We recommend that studies be conducted to validate laboratory proficiency testing as an important step in the prevention and control of the spread of antimicrobial resistance. PMID:10364577

  14. Laboratory investigations of stable carbon and oxygen isotope ratio data enhance monitoring of CO2 underground

    NASA Astrophysics Data System (ADS)

    Barth, Johannes A. C.; Myrttinen, Anssi; Becker, Veith; Nowak, Martin; Mayer, Bernhard

    2014-05-01

    Stable carbon and oxygen isotope data play an important role in monitoring CO2 in the subsurface, for instance during carbon capture and storage (CCS). This includes monitoring of supercritical and gaseous CO2 movement and reactions under reservoir conditions and detection of potential CO2 leakage scenarios. However, in many cases isotope data from field campaigns are either limited due to complex sample retrieval or require verification under controlled boundary conditions. Moreover, experimentally verified isotope fractionation factors are also accurately known only for temperatures and pressures lower than commonly found in CO2 reservoirs (Myrttinen et al., 2012). For this reason, several experimental series were conducted in order to investigate effects of elevated pressures, temperatures and salinities on stable carbon and oxygen isotope changes of CO2 and water. These tests were conducted with a heateable pressure device and with glass or metal gas containers in which CO2 reacted with fluids for time periods of hours to several weeks. The obtained results revealed systematic differences in 13C/12C-distributions between CO2 and the most important dissolved inorganic carbon (DIC) species under reservoir conditions (CO2(aq), H2CO3 and HCO3-). Since direct measurements of the pH, even immediately after sampling, were unreliable due to rapid CO2 de-gassing, one of the key results of this work is that carbon isotope fractionation data between DIC and CO2 may serve to reconstruct in situ pH values. pH values reconstructed with this approach ranged between 5.5 and 7.4 for experiments with 60 bars and up to 120 °C and were on average 1.4 pH units lower than those measured with standard pH electrodes directly after sampling. In addition, pressure and temperature experiments with H2O and CO2 revealed that differences between the oxygen isotope ratios of both phases depended on temperature, water-gas ratios as well as salt contents of the solutions involved. Such

  15. Canadian Public Health Laboratory Network laboratory guidelines for the use of direct tests to detect syphilis in Canada.

    PubMed

    Tsang, Raymond Sw; Morshed, Muhammad; Chernesky, Max A; Jayaraman, Gayatri C; Kadkhoda, Kamran

    2015-01-01

    Treponema pallidum subsp. pallidum and/or its nucleic acid can be detected by various methods such as microscopy, rabbit infectivity test or polymerase chain reaction (PCR) tests. The rabbit infectivity test for T. pallidum, although very sensitive, has been discontinued from most laboratories due to ethical issues related to the need for animal inoculation with live T. pallidum, the technically demanding procedure and long turnaround time for results, thus making it impractical for routine diagnostic use. Dark-field and phase-contrast microscopy are still useful at clinic- or hospital-based laboratories for near-bedside detection of T. pallidum in genital, skin or mucous lesions although their availability is decreasing. The lack of reliable and specific anti-T. pallidum antibodies and its inferior sensitivity to PCR may explain why the direct fluorescent antibody test for T. pallidum is not widely available for clinical use. Immunohistochemical staining for T. pallidum also depends on the availability of specific antibodies, and the method is only applicable for histopathological examination of biopsy and autopsy specimens necessitating an invasive specimen collection approach. With recent advances in molecular diagnostics, PCR is considered to be the most reliable, versatile and practical for laboratories to implement. In addition to being an objective and sensitive test for direct detection of Treponema pallidum subsp. pallidum DNA in skin and mucous membrane lesions, the resulting PCR amplicons from selected gene targets can be further characterized for antimicrobial (macrolide) susceptibility testing, strain typing and identification of T. pallidum subspecies. PMID:25798160

  16. Canadian Public Health Laboratory Network laboratory guidelines for the use of direct tests to detect syphilis in Canada

    PubMed Central

    Tsang, Raymond SW; Morshed, Muhammad; Chernesky, Max A; Jayaraman, Gayatri C; Kadkhoda, Kamran

    2015-01-01

    Treponema pallidum subsp. pallidum and/or its nucleic acid can be detected by various methods such as microscopy, rabbit infectivity test or polymerase chain reaction (PCR) tests. The rabbit infectivity test for T. pallidum, although very sensitive, has been discontinued from most laboratories due to ethical issues related to the need for animal inoculation with live T. pallidum, the technically demanding procedure and long turnaround time for results, thus making it impractical for routine diagnostic use. Dark-field and phase-contrast microscopy are still useful at clinic- or hospital-based laboratories for near-bedside detection of T. pallidum in genital, skin or mucous lesions although their availability is decreasing. The lack of reliable and specific anti-T. pallidum antibodies and its inferior sensitivity to PCR may explain why the direct fluorescent antibody test for T. pallidum is not widely available for clinical use. Immunohistochemical staining for T. pallidum also depends on the availability of specific antibodies, and the method is only applicable for histopathological examination of biopsy and autopsy specimens necessitating an invasive specimen collection approach. With recent advances in molecular diagnostics, PCR is considered to be the most reliable, versatile and practical for laboratories to implement. In addition to being an objective and sensitive test for direct detection of Treponema pallidum subsp. pallidum DNA in skin and mucous membrane lesions, the resulting PCR amplicons from selected gene targets can be further characterized for antimicrobial (macrolide) susceptibility testing, strain typing and identification of T. pallidum subspecies. PMID:25798160

  17. Implementation. Improving caries detection, assessment, diagnosis and monitoring.

    PubMed

    Pitts, N B

    2009-01-01

    This chapter deals with improving the detection, assessment, diagnosis and monitoring of caries to ensure optimal personalized caries management. This can be achieved by delivering what we have (synthesized evidence and international consensus) better and more consistently, as well as driving research and innovation in the areas where we need them. There is a need to better understand the interrelated pieces of the jigsaw that makes up evidence-based dentistry, i.e. the linkages between (a) research and synthesis, (b) dissemination of research results and (c) the implementation of research findings which should ensure that research findings change practice at the clinician-patient level. The current situation is outlined; it is at the implementation step where preventive caries control seems to have failed in some countries but not others. Opportunities for implementation include: capitalizing on the World Health Organization's global policy for improvement of oral health, which sets out an action plan for health promotion and integrated disease prevention; utilizing the developments around the International Caries Detection and Assessment System wardrobe of options and e-learning; building on initiatives from the International Dental Federation and the American Dental Association and linking these to patients' preferences, the wider moves to wellbeing and health maintenance. Challenges for implementation include the slow pace of evolution around dental remuneration systems and some groups of dentists failing to embrace clinical prevention. In the future, implementation of current and developing evidence should be accompanied by research into getting research findings into routine practice, with impacts on the behaviour of patients, professionals and policy makers. PMID:19494687

  18. Reference materials and intercomparison samples available from the Environmental Monitoring Systems Laboratory - Las Vegas

    SciTech Connect

    Kantor, E.J.; Laska, P.R.

    1985-06-01

    Reference materials and intercomparison samples may be obtained by laboratories involved in the analysis of environmental samples containing radioactivity, pesticides, toxic inorganic species, or toxic organic species. These reference materials and intercomparison samples are available from the US Environmental Protection Agency's Quality Assurance Division located at the Environmental Monitoring Systems Laboratory in Las Vegas (EMSL-LV). These materials are useful for incorporation into a laboratory's quality control program for the evaluation of the precision and accuracy of analytical work. Media used for radiation reference materials are pitchblende, Monazite ore, uranium mill tailings, Mancos shale, fly ash, and water spiked with radionuclides. Radioactivity intercomparison samples consist of water, milk, air, urine, and a simulated diet slurry spiked with radionuclides. Media available for toxic organic reference materials are sludge, shale oil, and rag oil, and for intercomparison samples are soil and water. Characterized fly ash, foundry sludge, and river sediment serve as reference materials for toxic inorganics, while spiked soil and water serve as intercomparison samples. Finally, spiked adipose tissue, blood plasma, urine, and water comprise the pesticide intercomparison samples, and, after the disclosure of the true pesticide compositions and concentrations of these samples, the laboratory can use the samples as reference materials. The reference materials are generally available continuously, but the intercomparison samples are distributed on a scheduled basis and in some cases only to certain laboratories. 9 tables.

  19. 1998 Environmental Monitoring Program Report for the Idaho National Engineering and Environmental Laboratory

    SciTech Connect

    L. V. Street

    1999-09-01

    This report describes the calendar year 1998 compliance monitoring and environmental surveillance activities of the Lockheed Martin Idaho Technologies Company Environmental Monitoring Program performed at the Idaho National Engineering and Environmental Laboratory. This report includes results of sampling performed by the Drinking Water, Effluent, Storm Water, Groundwater Monitoring, and Environmental Surveillance Programs. This report compares the 1998 results to program-specific regulatory guidelines and past data to evaluate trends. The primary purposes of the monitoring and surveillance activities are to evaluate environmental conditions, to provide and interpret data, to verify compliance with applicable regulations or standards, and to ensure protection of public health and the environment. Surveillance of environmental media did not identify any previously unknown environmental problems or trends, which would indicate a loss of control or unplanned releases from facility operations. The INEEL complied with permits and applicable regulations, with the exception of nitrogen samples in a disposal pond effluent stream and iron and total coliform bacteria in groundwater downgradient from one disposal pond. Data collected by the Environmental Monitoring Program demonstrate that the public health and environment were protected.

  20. Promoting early exposure monitoring for respirable crystalline silica: Taking the laboratory to the mine site.

    PubMed

    Cauda, Emanuele; Miller, Arthur; Drake, Pamela

    2016-01-01

    The exposure to respirable crystalline silica (RCS) in the mining industry is a recognized occupational hazard. The assessment and monitoring of the exposure to RCS is limited by two main factors: (1) variability of the silica percent in the mining dust and (2) lengthy off-site laboratory analysis of collected samples. The monitoring of respirable dust via traditional or real-time techniques is not adequate. A solution for on-site quantification of RCS in dust samples is being investigated by the Office of Mine Safety and Health Research, a division of the National Institute for Occupational Safety and Health. The use of portable Fourier transform infrared analyzers in conjunction with a direct-on-filter analysis approach is proposed. The progress made so far, the necessary steps in progress, and the application of the monitoring solution to a small data set is presented. When developed, the solution will allow operators to estimate RCS immediately after sampling, resulting in timelier monitoring of RCS for self-assessment of compliance at the end of the shift, more effective engineering monitoring, and better evaluation of control technologies. PMID:26558490

  1. Laboratory Detection of Clostridium difficile in Piglets in Australia

    PubMed Central

    Knight, Daniel R.; Squire, Michele M.

    2014-01-01

    Clostridium difficile is a well-known enteric pathogen of humans and the causative agent of high-morbidity enteritis in piglets aged 1 to 7 days. C. difficile prevalence in Australian piglets is as high as 70%. The current diagnostic assays have been validated only for human infections, and there are no published studies assessing their performance in Australian piglets. We evaluated the suitability of five assays for detecting C. difficile in 157 specimens of piglet feces. The assays included a loop-mediated isothermal amplification (LMIA)-PCR for tcdA (illumigene C. difficile; Meridian), a real-time PCR for tcdB (GeneOhm Cdiff; Becton Dickinson), two-component enzyme immunoassays (EIA) for C. difficile glutamate dehydrogenase (GDH) (EIA-GDH) and TcdA/TcdB (EIA-TcdA/TcdB) (C. diff Quik Chek; Alere), and direct culture (DC) (C. difficile chromID agar; bioMérieux). The assays for detection of the organism were compared against enrichment culture (EC), and assays for detection of toxins/toxin genes were compared against EC followed by PCR for toxin genes (toxigenic EC [TEC]). The recovery of C. difficile by EC was 39.5% (n = 62/157), and TEC revealed that 58.1% (n = 36/62) of isolates were positive for at least one toxin gene (tcdA/tcdB). Compared with those for EC/TEC, the sensitivities, specificities, positive predictive values, and negative predictive values were, respectively, as follows: DC, 91.9, 100.0, 100.0, and 95.0%; EIA-GDH, 41.9, 92.6, 78.8, and 71.0%; EIA-TcdA/TcdB, 5.6, 99.2, 66.7, and 77.9%; real-time PCR, 42.9, 96.7, 78.9, and 85.4% and LMIA-PCR, 25.0, 95.9, 64.3, and 81.1%. The performance of the molecular methods was poor, suggesting that the current commercially available assays for diagnosis of C. difficile in humans are not suitable for use in piglets. C. difficile recovery by the DC provides a cost-effective alternative. PMID:25122859

  2. Structural health monitoring and probability of detection estimation

    NASA Astrophysics Data System (ADS)

    Forsyth, David S.

    2016-02-01

    Structural health monitoring (SHM) methods are often based on nondestructive testing (NDT) sensors and are often proposed as replacements for NDT to lower cost and/or improve reliability. In order to take advantage of SHM for life cycle management, it is necessary to determine the Probability of Detection (POD) of the SHM system just as for traditional NDT to ensure that the required level of safety is maintained. Many different possibilities exist for SHM systems, but one of the attractive features of SHM versus NDT is the ability to take measurements very simply after the SHM system is installed. Using a simple statistical model of POD, some authors have proposed that very high rates of SHM system data sampling can result in high effective POD even in situations where an individual test has low POD. In this paper, we discuss the theoretical basis for determining the effect of repeated inspections, and examine data from SHM experiments against this framework to show how the effective POD from multiple tests can be estimated.

  3. Singularity detection for structural health monitoring using holder exponents.

    SciTech Connect

    Robertson, A. N.; Farrar, C. R.; Sohn, H.

    2003-01-01

    The majority of structural health monitoring studies reported in the technical literature focus on identifying damage sensitive features that can be extracted from dynamic response data . However, many of these studies assume the structure can be modeled as a linear system before and after damage and use parameters of these models as the damage sensitive features. The study summarized in this paper proposes a damage sensitive feature that takes advantage of the nonlinearities associated with discontinuities introduced into the dynamic response data as a result of certain types of damage. Specifically, the Holder exponent, a measure of the degree to which a signal is differentiable, is the feature that is used to detect the presence of damage and when that damage occurred . A procedure for capturing the time varying nature of the Holder exponent based on wavelet transforms is demonstrated through applications to non-stationary random signals with underlying discontinuities and then to a harmonically excited mechanical system that contains a loose part . Also, a classification procedure is developed to quantify when changes in the Holder exponent are significant . The results presented herein show the Holder exponent to be an effective feature for identifying damage that introduces discontinuities into the measured dynamic response data .

  4. Improved monitoring of subsurface CO2 storage using novel electrical and seismic measurements: scaled laboratory studies

    NASA Astrophysics Data System (ADS)

    Ghose, R.; Kirichek, A.; Draganov, D.; Heller, K.

    2013-05-01

    For monitoring CO2 stored in appropriate geological settings like depleted oil or gas reservoirs, deep saline aquifers and deep unminable coalbeds, geophysical methods e.g., seismic, electromagnetics, gravity, and surface deformation studies serve as remote sensing techniques which generally provide a large coverage but a low spatial resolution. It has been concluded that of the various approaches, seismic methods have the broadest applicability for stored CO2 monitoring in various geologic settings. As a result, advanced and dedicated seismic monitoring techniques have been developed. However, three major issues that remain unresolved are: 1) to remove accurately the effect of the overburden layers in order to capture the change in seismic properties in the reservoir and thereby obtain reliable estimates of temporal and spatial changes of the rock-physical properties like pressure and saturation, 2) the difficulty to minimize the source-related variation in time-lapse seismic, and 3) the inability to monitor the changes in phase (supercritical, liquid or gaseous) of the stored CO2 in time and space. In order to address these crucial issues, we have concentrated on scaled laboratory tests mimicking realistic storage conditions, and have tested novel approaches involving analysis of complex electrical impedance coupled with seismic-interferometric characterization. A new laboratory experimental facility for simultaneous, multichannel seismic and AC electrical measurements has been developed. We have found that electrical permittivity is a very sensitive parameter to monitor the phase of the stored CO2. Secondly, a novel approach has been developed, which takes advantage of the nonphysical reflections retrieved by seismic interferometry to estimate reliable values of seismic wave velocity and attenuation in the CO2 reservoir, efficiently minimizing the effect of the overburden and removing the detrimental effect of the source-related irreproducibility. Finally, new

  5. Knolls Atomic Power Laboratory annual environmental monitoring report. Calendar Year 1993

    SciTech Connect

    Not Available

    1993-12-31

    The results of the effluent and environmental monitoring programs at the three Knolls Atomic Power Laboratory (KAPL) sites are summarized and assessed in this report. Operations at the three KAPL sites resulted in no significant release of hazardous substances or radioactivity to the environment. The effluent and environmental monitoring programs conducted by KAPL are designed to determine the effectiveness of treatment and control methods, to provide measurement of the concentrations in effluents for comparison with applicable standards, and to assess resultant concentrations in the environment. The monitoring programs include analyses of samples of liquid and gaseous effluents for chemical constituents and radioactivity as well as monitoring of environmental air, water, sediment, and fish. Radiation measurements are also made around the perimeter of each site and at off-site background locations. KAPL environmental controls are subject to applicable state and federal regulations governing use, emission, treatment, storage and/or disposal of solid, liquid and gaseous materials. Some non-radiological water and air emissions are generated and treated on-site prior to discharge to the environment. Liquid effluents and air emissions are controlled and monitored in accordance with permits issued by the Connecticut Department of Environmental Protection (CTDEP) for the Windsor Site and by the New York State Department of Environmental Conservation (NYSDEC) for the Knolls and Kesselring Sites. The liquid effluent monitoring data show that KAPL has maintained a high degree of compliance with permit requirements. Where required, radionuclide air emission sources are authorized by the US Environmental Protection Agency (EPA). The non-radiological air emissions, with the exception of opacity for the boilers, are not required to be monitored.

  6. Detection of intestinal protozoa in the clinical laboratory.

    PubMed

    McHardy, Ian H; Wu, Max; Shimizu-Cohen, Robyn; Couturier, Marc Roger; Humphries, Romney M

    2014-03-01

    Despite recent advances in diagnostic technology, microscopic examination of stool specimens remains central to the diagnosis of most pathogenic intestinal protozoa. Microscopy is, however, labor-intensive and requires a skilled technologist. New, highly sensitive diagnostic methods have been developed for protozoa endemic to developed countries, including Giardia lamblia (syn. G. intestinalis/G. duodenalis) and Cryptosporidium spp., using technologies that, if expanded, could effectively complement or even replace microscopic approaches. To date, the scope of such novel technologies is limited and may not include common protozoa such as Dientamoeba fragilis, Entamoeba histolytica, or Cyclospora cayetanensis. This minireview describes canonical approaches for the detection of pathogenic intestinal protozoa, while highlighting recent developments and FDA-approved tools for clinical diagnosis of common intestinal protozoa. PMID:24197877

  7. Establishment of the Radiation Detection Laboratory at Fisk University

    SciTech Connect

    Arnold Burger, Ph.D.

    2008-02-28

    Synthetic CdZnTe (CZT) semiconducting crystals are highly suitable for the room temperature-based detection of gamma radiation. The surface preparation of Au contacts on surfaces of CZT detectors is typically conducted after (1) polishing to remove artifacts from crystal sectioning and (2) chemical etching, which removes residual mechanical surface damage however etching results in a Te rich surface layer that is prone to oxidize. Our studies show that CZT surfaces that are only polished (as opposed to polished and etched) can be contacted with Au and will yield lower surface currents. Due to their decreased dark currents, these as-polished surfaces can be used in the fabrication of gamma detectors exhibiting a higher performance than polished and etched surfaces with relatively less peak tailing and greater energy resolution.032}

  8. Detection of Intestinal Protozoa in the Clinical Laboratory

    PubMed Central

    McHardy, Ian H.; Wu, Max; Shimizu-Cohen, Robyn; Couturier, Marc Roger

    2014-01-01

    Despite recent advances in diagnostic technology, microscopic examination of stool specimens remains central to the diagnosis of most pathogenic intestinal protozoa. Microscopy is, however, labor-intensive and requires a skilled technologist. New, highly sensitive diagnostic methods have been developed for protozoa endemic to developed countries, including Giardia lamblia (syn. G. intestinalis/G. duodenalis) and Cryptosporidium spp., using technologies that, if expanded, could effectively complement or even replace microscopic approaches. To date, the scope of such novel technologies is limited and may not include common protozoa such as Dientamoeba fragilis, Entamoeba histolytica, or Cyclospora cayetanensis. This minireview describes canonical approaches for the detection of pathogenic intestinal protozoa, while highlighting recent developments and FDA-approved tools for clinical diagnosis of common intestinal protozoa. PMID:24197877

  9. Current limitations and challenges in nanowaste detection, characterisation and monitoring

    SciTech Connect

    Part, Florian; Zecha, Gudrun; Causon, Tim; Sinner, Eva-Kathrin

    2015-09-15

    Highlights: • First review on detection of nanomaterials in complex waste samples. • Focus on nanoparticles in solid, liquid and gaseous waste samples. • Summary of current applicable methods for nanowaste detection and characterisation. • Limitations and challenges of characterisation of nanoparticles in waste. - Abstract: Engineered nanomaterials (ENMs) are already extensively used in diverse consumer products. Along the life cycle of a nano-enabled product, ENMs can be released and subsequently accumulate in the environment. Material flow models also indicate that a variety of ENMs may accumulate in waste streams. Therefore, a new type of waste, so-called nanowaste, is generated when end-of-life ENMs and nano-enabled products are disposed of. In terms of the precautionary principle, environmental monitoring of end-of-life ENMs is crucial to allow assessment of the potential impact of nanowaste on our ecosystem. Trace analysis and quantification of nanoparticulate species is very challenging because of the variety of ENM types that are used in products and low concentrations of nanowaste expected in complex environmental media. In the framework of this paper, challenges in nanowaste characterisation and appropriate analytical techniques which can be applied to nanowaste analysis are summarised. Recent case studies focussing on the characterisation of ENMs in waste streams are discussed. Most studies aim to investigate the fate of nanowaste during incineration, particularly considering aerosol measurements; whereas, detailed studies focusing on the potential release of nanowaste during waste recycling processes are currently not available. In terms of suitable analytical methods, separation techniques coupled to spectrometry-based methods are promising tools to detect nanowaste and determine particle size distribution in liquid waste samples. Standardised leaching protocols can be applied to generate soluble fractions stemming from solid wastes, while

  10. Facility Effluent Monitoring Plan for Pacific Northwest National Laboratory Balance-of-Plant Facilities

    SciTech Connect

    Ballinger, M.Y.; Shields, K.D.

    1999-04-02

    The Pacific Northwest National Laboratory (PNNL) operates a number of research and development (R and D) facilities for the Department of Energy on the Hanford Site. According to DOE Order 5400.1, a Facility Effluent Monitoring Plan is required for each site, facility, or process that uses, generates, releases, or manages significant pollutants or hazardous materials. Three of the R and D facilities: the 325, 331, and 3720 Buildings, are considered major emission points for radionuclide air sampling and thus individual Facility Effluent Monitoring Plans (FEMPs) have been developed for them. Because no definition of ''significant'' is provided in DOE Order 5400.1 or the accompanying regulatory guide DOE/EH-0173T, this FEMP was developed to describe monitoring requirements in the DOE-owned, PNNL-operated facilities that do not have individual FEMPs. The remainder of the DOE-owned, PNNL-operated facilities are referred to as Balance-of-Plant (BOP) facilities. Activities in the BOP facilities range from administrative to laboratory and pilot-scale R and D. R and D activities include both radioactive and chemical waste characterization, fluid dynamics research, mechanical property testing, dosimetry research, and molecular sciences. The mission and activities for individual buildings are described in the FEMP.