Science.gov

Sample records for multisite spectroscopic observations

  1. Coordinated Multi-Site and Multi-Wavelength Observing Campaigns

    NASA Astrophysics Data System (ADS)

    Butler, C. J.

    1994-03-01

    A brief description is given of: (1) a newsletter which has been established to notify interested observers of future collaborative programmes, (2) MUSICOS, a group which organizes multisite, continuous spectroscopy, and (3) a computer program which has been written to assist in the coordination of simultaneous observations from ground-based and satellite telescopes.

  2. Multisite spectroscopic seismic study of the β Cep star V2052 Ophiuchi: inhibition of mixing by its magnetic field

    NASA Astrophysics Data System (ADS)

    Briquet, M.; Neiner, C.; Aerts, C.; Morel, T.; Mathis, S.; Reese, D. R.; Lehmann, H.; Costero, R.; Echevarria, J.; Handler, G.; Kambe, E.; Hirata, R.; Masuda, S.; Wright, D.; Yang, S.; Pintado, O.; Mkrtichian, D.; Lee, B. C.; Han, I.; Bruch, A.; De Cat, P.; Uytterhoeven, K.; Lefever, K.; Vanautgaerden, J.; de Batz, B.; Frémat, Y.; Henrichs, H.; Geers, V. C.; Martayan, C.; Hubert, A. M.; Thizy, O.; Tijani, A.

    2012-11-01

    We used extensive ground-based multisite and archival spectroscopy to derive observational constraints for a seismic modelling of the magnetic β Cep star V2052 Ophiuchi. The line-profile variability is dominated by a radial mode (f1 = 7.148 46 d-1) and by rotational modulation (Prot = 3.638 833 d). Two non-radial low-amplitude modes (f2 = 7.756 03 d-1 and f3 = 6.823 08 d-1) are also detected. The four periodicities that we found are the same as the ones discovered from a companion multisite photometric campaign and known in the literature. Using the photometric constraints on the degrees ℓ of the pulsation modes, we show that both f2 and f3 are prograde modes with (ℓ, m) = (4, 2) or (4, 3). These results allowed us to deduce ranges for the mass (M ∈ [8.2, 9.6] M⊙) and central hydrogen abundance (Xc ∈ [0.25, 0.32]) of V2052 Oph, to identify the radial orders n1 = 1, n2 = -3 and n3 = -2, and to derive an equatorial rotation velocity veq ∈ [71, 75] km s-1. The model parameters are in full agreement with the effective temperature and surface gravity deduced from spectroscopy. Only models with no or mild core overshooting (αov ∈ [0, 0.15] local pressure scale heights) can account for the observed properties. Such a low overshooting is opposite to our previous modelling results for the non-magnetic β Cep star θ Oph having very similar parameters, except for a slower surface rotation rate. We discuss whether this result can be explained by the presence of a magnetic field in V2052 Oph that inhibits mixing in its interior.

  3. A gridded multisite weather generator and synchronization to observed weather data

    NASA Astrophysics Data System (ADS)

    Wilks, Daniel S.

    2009-10-01

    Procedures are described for constructing a daily multisite weather generator at a collection of arbitrary (e.g., gridded) locations and for synchronizing the gridded generator to observed weather series at a set of reference stations. The gridded generator is constructed by interpolating conventional single-station weather generator parameters using locally weighted regressions and producing coherent simulations of daily weather from them using spatial correlation functions. When implemented, the synchronization algorithm results in simulated spatial weather fields at the grid points that are consistent with daily weather observations at nearby locations for particular years. The synchronization is achieved by exploiting the latent multivariate Gaussian structure of the spatially distributed weather generator and making use of well-known statistical results that define conditional multivariate Gaussian distributions given known values for a subset of variables from the larger joint distribution. The primary focus is on precipitation, but the nonprecipitation variables in the weather generator are also amenable to gridding and to synchronization with nearby observed weather series. The motivating idea is to allow calibration of spatially distributed hydrological models consistent with the climate of the spatial weather generator, potentially allowing more realistic hydrological simulation, but the procedure may also be useful for interpolation of missing daily weather data.

  4. AstroNet: A Tool Set for Simultaneous, Multi-Site Observations of Astronomical Objects

    NASA Technical Reports Server (NTRS)

    Chakrabarti, Supriya

    1995-01-01

    Earth-based, fully automatic "robotic" telescopes have been in routine operation for a number of years. As their number grows and their distribution becomes global, increasing attention is being given to forming networks of various sorts that will allow them, as a group, to make observations 24 hours a day in both hemispheres. We have suggested that telescopes based in space be part of this network. We further suggested that any telescope on this network be capable of asking, almost in real time, that other robotic telescopes perform support observations for them. When a target of opportunity required support observations, the system would determine which telescope(s) in the network would be most appropriate to make the observations and formulate a request to do so. Because the network would be comprised of telescopes located in widely distributed regions, this system would guarantee continuity of observations This report summarizes our efforts under this contract. We proposed to develop a set of data collection and display tools to aid simultaneous observation of astronomical targets from a number of observing sites. We planned to demonstrate the usefulness of this toolset for simultaneous multi-site observation of astronomical targets. Possible candidates or the proposed demonstration included the Extreme Ultraviolet Explorer (EUVE), International Ultraviolet Explorer (IUE), and ALEXIS, sounding rocket experiments. Ground-based observatories operated by the University of California, Berkeley, the Jet Propulsion Laboratory, and Fairborn Observatory in Mesa, Arizona were to be used to demonstrate the proposed concept. Although the demonstration was to have involved astronomical investigations, the tools were to have been applicable to a large number of scientific disciplines. The software tools and systems developed as a result of the work were to have been made available to the scientific community.

  5. Spectroscopic observations of cool degenerate star candidates

    NASA Technical Reports Server (NTRS)

    Hintzen, P.

    1986-01-01

    Spectroscopic observations are reported for 23 Luyten Half-Second degenerate star candidates and for 13 Luyten-Palomar common proper-motion pairs containing possible degenerate star components. Twenty-five degenerate stars are identified, 20 of which lack previous spectroscopy. Most of these stars are cool - Luyten color class g or later. One star, LP 77-57, shows broad continuum depressions similar to those in LHS 1126, which Liebert and Dahn attributed to pressure-shifted C2. A second degenerate star, LHS 290, exhibits apparent strong Swan bands which are blueshifted about 75 A. Further observations, including polarimetry and photometry, are required to appraise the spectroscopic peculiarities of these stars. Finally, five cool, sharp-lined DA white dwarfs have been observed to detect lines of metals and to determine line strengths. None of these DAs show signs of Mg b or the G band, and four show no evidence of Ca II K. The attempt to detect Ca MI in the fifth star, G199-71, was inconclusive.

  6. The first spectroscopic observation of germanium carbide

    NASA Astrophysics Data System (ADS)

    Ruiz, Jose I.

    Electronic spectroscopy was used to obtain gas phase spectrum of the germanium carbide molecule in emission from a corona excited supersonic expansion source. The (2) 3pi -- X 3pi electronic transition was observed around the 21250 cm-1 region. In this system, vibrational bands and the rotational lines of the O = 0, 1, and 2 components were obtained and analyzed. The equilibrium transition energy is found at 21120.3 cm-1 and the fundamental vibrational frequency for the lowest energy ground state O = 2 component is 795.3 cm -1. This is the first spectroscopic observation of germanium carbide. An unsuccessful attempt to obtain the first electronic emission spectrum of aluminum boride is also described.

  7. Spectroscopic Observations of Nearby Low Mass Stars

    NASA Astrophysics Data System (ADS)

    Vican, Laura; Zuckerman, B. M.; Rodriguez, D.

    2014-01-01

    Young low-mass stars are known to be bright in X-ray and UV due to a high level of magnetic activity. By cross-correlating the GALEX Catalog with the WISE and 2MASS Point Source Catalogs, we have identified more than 2,000 stars whose UV excesses suggest ages in the 10-100 Myr range. We used the Shane 3-m telescope at Lick Observatory on Mount Hamilton, California to observe some of these 2,000 stars spectroscopically. We measured the equivalent width of lithium at 6708 A absorption and H-alpha emission lines. Out of a total of 122 stars observed with the Kast grating spectrometer, we find that roughly 10% have strong lithium absorption features. The high percentage of stars with lithium present is further evidence of the importance of UV emission as a youth indicator for low-mass stars. In addition, we used high-resolution spectra obtained with the Hamilton echelle spectrograph to determine radial velocities for several UV-bright stars. These radial velocities will be useful for the calculation of Galactic UVW space velocities for determination of possible moving group membership. This work is supported by NASA Astrophysics Data Analysis Program award NNX12AH37G to RIT and UCLA and Chilean FONDECYT grant 3130520 to Universidad de Chile. This submission presents work for the GALNYSS project and should be linked to abstracts submitted by David Rodriguez, Laura Vican, and Joel Kastner.

  8. Using a Two-Staged Propensity Score Matching Strategy and Multilevel Modeling to Estimate Treatment Effects in a Multisite Observational Study

    ERIC Educational Resources Information Center

    Rickles, Jordan H.

    2012-01-01

    The study is designed to demonstrate and test the utility of the proposed two-stage matching method compared to other analytic methods traditionally employed for multisite observational studies. More specifically, the study addresses the following research questions: (1) How do different specifications of the matching method influence covariate…

  9. Correlations of experimental isotope shifts with spectroscopic and mass observables

    SciTech Connect

    Cakirli, R. B.; Casten, R. F.; Blaum, K.

    2010-12-15

    Experimental differential observables relating to mean square charge radii, spectroscopic, and mass observables of even-even nuclei are presented for different regions in the nuclear chart. They exhibit remarkable correlations, not heretofore recognized, that provide a new perspective on structural evolution, especially in exotic nuclei. This can also be a guide for future measurements of charge radii, spectroscopic observables, and masses, as well as for future theoretical approaches.

  10. A Two-Stage Propensity Score Matching Strategy for Treatment Effect Estimation in a Multisite Observational Study

    ERIC Educational Resources Information Center

    Rickles, Jordan H.; Seltzer, Michael

    2014-01-01

    When nonrandom treatments occur across sites, within-site matching (WM) is often desirable. This approach, however, can significantly reduce treatment group sample size and exclude substantively important subgroups. To limit these drawbacks, we extend a matching approach developed by Stuart and Rubin to a multisite study. We demonstrate the…

  11. GROUND-BASED MULTISITE OBSERVATIONS OF TWO TRANSITS OF HD 80606b

    SciTech Connect

    Shporer, A.; Winn, J. N.; Dreizler, S.; Colon, K. D.; Wood-Vasey, W. M.; Cerutti, S.; Coban, L.; Costello, K.; Choi, P. I.; Morley, C.; Adams, E.; Moutou, C.; Welsh, W. F.; Pollaco, D.; Barros, S. C. C.; Starkey, D.; Bouchy, F.; DIaz, R. F.; Cabrera-Lavers, A.; Deeg, H.

    2010-10-10

    We present ground-based optical observations of the 2009 September and 2010 January transits of HD 80606b. Based on three partial light curves of the 2009 September event, we derive a midtransit time of T{sub c} [HJD] = 2455099.196 {+-} 0.026, which is about 1{sigma} away from the previously predicted time. We observed the 2010 January event from nine different locations, with most phases of the transit being observed by at least three different teams. We determine a midtransit time of T{sub c} [HJD] = 2455210.6502 {+-} 0.0064, which is within 1.3{sigma} of the time derived from a Spitzer observation of the same event.

  12. Patient compliance with postoperative analgesia after day case surgery: a multisite observational study of patients in North East London

    PubMed Central

    Fahmy, Nisreen; Siah, Julian; Umo-Etuk, Joanna

    2016-01-01

    Background: Pain is the commonest reason for delayed discharge and readmission post day surgery with up to 45% of patients reported to suffer moderate-to-severe post-surgical pain 24 hours after discharge. The importance of post-surgical pain management extends beyond the acute phase when one considers that all chronic post-surgical pain was once acute. Although much focus is given to perioperative analgesia, a patient’s pain management once discharged can be overlooked, whilst at this time the patient’s pain management is within their own hands. Methods: We conducted this multisite observational study of adult patients undergoing day case surgery. After obtaining patient consent data was collected on the operation, intra- and postoperative analgesia administered and discharge analgesia prescribed. Patients were then contacted at home by telephone 48 hours after discharge and asked about their postoperative pain and analgesia requirements. Results: Of 150 patients consented for the enrolment, we were able to obtain postoperative analgesia data on 100. A total of 68% of patients reported pain following discharge with 26% reporting severe pain, defined as a pain score of ⩾7. A total 68% of patients were prescribed and dispensed analgesia, and of those, 83% were compliant with their analgesia. Thus, we conclude that in this patient group, the incidence of postoperative pain was not due to lack of patient compliance, but inadequate analgesia prescription. Discussion: We recognise that our data reflect a patient population in North East London but suggest that the results may still be relevant to a wider patient group across the United Kingdom as the incidence of postoperative pain in our study was similar to published figures. Better patient satisfaction with postoperative analgesia may be obtained with more patient- and surgery-specific analgesic prescription. PMID:27551418

  13. Using and Experiencing the Academic Library: A Multisite Observational Study of Space and Place

    ERIC Educational Resources Information Center

    May, Francine; Swabey, Alice

    2015-01-01

    This study examines how students are using academic library spaces and the role these spaces are playing in the campus community. Data were collected on five campuses (two community colleges, two undergraduate universities, and one technical institute) via observational seating sweeps and questionnaires. The study found remarkably similar usage…

  14. Seasonal Variation of Methane Emissions in California's Urban and Rural Regions Using Multi-site Observations

    NASA Astrophysics Data System (ADS)

    Jeong, S.; Hsu, Y.; Andrews, A. E.; Bianco, L.; Newman, S.; Cui, X.; Bagley, J.; Graven, H. D.; Salameh, P.; Sloop, C.; LaFranchi, B.; Michelsen, H. A.; Bambha, R.; Weiss, R. F.; Keeling, R. F.; Fischer, M. L.

    2014-12-01

    California's commitment (Assembly Bill 32) to reduce total greenhouse gas (GHG) emissions to 1990 levels by 2020 requires quantification of current GHG emissions. We present seasonal variation of California's total CH4 emissions for summer 2013 - spring 2014, using data from a dozen sites covering urban and rural areas of California that include South Coast Air Basin (SoCAB), Central Valley, and San Francisco Bay Area. We apply a Bayesian inverse model to estimate CH4 emissions from discrete regions of California and source sectors by combining atmospheric measurements, upstream background, updated high-resolution prior emission maps developed for California, and predicted atmospheric transport from WRF-STILT. We quantify site-specific model-measurement uncertainties due to transport using simulated and observed meteorology, background estimated from oceanic and aircraft observations, and the prior emissions. In particular, we evaluate predicted transport variables in WRF with networks of surface and upper air observations. Preliminary inversion results during summer of 2013 suggest that state total CH4 emissions are 1.2 - 1.7 times higher than the current CARB inventory. Here, we extend and improve upon earlier analyses to provide a full seasonal cycle of CH4 emissions across all major urban and rural regions in California.

  15. The first spectroscopic observation of germanium carbide

    NASA Astrophysics Data System (ADS)

    Brazier, Christopher R.; Ruiz, José I.

    2011-11-01

    The gas phase spectrum of the germanium carbide radical has been observed at low temperature in emission from a corona excited supersonic expansion source. Many vibrational bands involving the Ω = 0, 1, and 2 components of the (2) 3Π-X 3Π system were recorded and analyzed. The equilibrium transition energy is found at 21120.3 cm -1, in good agreement with theoretical predictions. The fundamental vibrational frequency for the lowest energy ground state Ω = 2 component is 795.3 cm -1.

  16. Spectroscopic observations of spatial and temporal variations on Venus

    NASA Technical Reports Server (NTRS)

    Young, A. T.; Young, L. G.; Woszczyk, A.

    1974-01-01

    Details of the Table Mountain spectroscopic patrol of Venus in September-October 1972 are given. The data indicate systematic variation over the disc, with more CO2 absorption near the terminator than at the limb, and slightly more in the southern than in the northern hemisphere. The semiregular four-day variation, reported to occur simultaneously over the disk at 8689 A by Young et al. (1973), is confirmed by observations of the 7820 A and 7883 A CO2 bands.

  17. Spectroscopic Observations of Fe XVIII in Solar Active Regions

    NASA Astrophysics Data System (ADS)

    Teriaca, Luca; Warren, Harry P.; Curdt, Werner

    2012-08-01

    The large uncertainties associated with measuring the amount of high temperature emission in solar active regions (ARs) represents a significant impediment to making progress on the coronal heating problem. Most current observations at temperatures of 3 MK and above are taken with broadband soft X-ray instruments. Such measurements have proven difficult to interpret unambiguously. Here, we present the first spectroscopic observations of the Fe XVIII 974.86 Å emission line in an on-disk AR taken with the SUMER instrument on SOHO. Fe XVIII has a peak formation temperature of 7.1 MK and provides important constraints on the amount of impulsive heating in the corona. Detailed evaluation of the spectra and comparison of the SUMER data with soft X-ray images from the X-Ray Telescope on Hinode confirm that this line is unblended. We also compare the spectroscopic data with observations from the Atmospheric Imaging Assembly (AIA) 94 Å channel on the Solar Dynamics Observatory. The AIA 94 Å channel also contains Fe XVIII, but is blended with emission formed at lower temperatures. We find that it is possible to remove the contaminating blends and form relatively pure Fe XVIII images that are consistent with the spectroscopic observations from SUMER. The observed spectra also contain the Ca XIV 943.63 Å line that, although a factor 2-6 weaker than the Fe XVIII 974.86 Å line, allows us to probe the plasma around 3.5 MK. The observed ratio between the two lines indicates (isothermal approximation) that most of the plasma in the brighter Fe XVIII AR loops is at temperatures between 3.5 and 4 MK.

  18. Spectroscopic Observations of the Recent M33 Nova Candidate

    NASA Astrophysics Data System (ADS)

    Shafter, A. W.; Ciardullo, R.; Bode, M. F.; Darnley, M. J.; Misselt, K. A.

    2010-10-01

    We report spectroscopic observations of the recent M33 nova candidate (M33N 2010-10a?), which was discovered by K. Nishiyama and F. Kabashima (Miyaki-Argenteus Observatory, Japan) on 2010 Oct. 26.65 UT. At our request a spectrum (410-950 nm) of the nova candidate was obtained by John Caldwell on 2010 Oct. 28.37 UT (~2 days post discovery) with the Marcario Low-Resolution Spectrograph on the 9.2m Hobby-Eberly Telescope.

  19. Carnegie Supernova Project: Spectroscopic Observations of Core Collapse Supernovae

    NASA Astrophysics Data System (ADS)

    Morrell, Nidia I.

    2012-09-01

    The Carnegie Supernova Project (CSP) has performed, during the period 2004-2009, the optical and NIR follow up of 253 supernovae (SNe) of all types. Among those, 124 were core collapse events, comprising 93 SNe of type II and 31 of types Ib/Ic/IIb. Our follow up consisted of photometric observations suitable to build detailed light curves and a considerable amount of optical spectroscopy. The bulk of our observations is carried out at Las Campanas Observatory, while access to other facilities is also provided thanks to our strong collaboration with the Millennium Center for Supernova Studies (MCSS). Our spectroscopic observations were primarily aimed at typing possible new SNe, and follow-up the evolution of CSP targets. One of the goals of the follow-up of type II SNe is the application of independent distance indicators such as the Standard Candle (SCM) and the Expanding Photosphere (EPM) methods. Moreover, through the study of the spectroscopic evolution of these objects, from as early as possible after explosion to the nebular phases, we hope to contribute to their further understanding. Specific analysis of particular objects is underway by members of the CSP and an extended collaboration.

  20. Employing Multiple Spectroscopic Techniques Simultaneously to Observe Protein Unfolding

    NASA Astrophysics Data System (ADS)

    Crowe, Michael; Kelty, Ben; Link, Justin

    2015-03-01

    A protein's function is directly related to its native, folded structure. In order to study the structure of proteins, the unfolding process may be characterized. In our study, by using the spectroscopic techniques of circular dichroism (CD), absorption, and fluorescence simultaneously, we examined the unfolding of horse heart cytochrome c, a well-studied, model protein by gradually increasing the concentration of the chemical denaturant, guanidine hydrochloride. The signal changes from these modalities over the course of the unfolding reaction provides some of the thermodynamic properties like Gibbs free energy for insight into the stability of the protein. This allows us to compare the three techniques under the exact same conditions. The objective of this session is to present recent work in developing a protocol to observe the unfolding of cytochrome c using fluorescence, absorbance, and CD simultaneously.

  1. Spectroscopic observations of the dwarf nova IP Pegasi

    SciTech Connect

    Hessman, F.V. )

    1989-08-01

    Time-resolved spectroscopic measurements of IP Peg were obtained immediately after a dwarf nova eruption. The radio-velocity amplitude of the white dwarf (118 + or - 10 km/s) implied by measurements from the wings of the Balmer emission lines is different from that found previously. The results suggest a mass ratio M1/M2 of 0.435 + or - 0.052 and that the narrow component is due to unusually strong chromospheric emission from the late-type star. The low value for the radial-velocity amplitude of this narrow emission (about 200 km/s) is consistent with the observed absorption-line amplitude of 331 km/s if the irradiated surface of the M dwarf produces little line absorption. 40 refs.

  2. Spectroscopic and video observations of fullerene production arcs

    SciTech Connect

    Lorents, D.C.; Stalder, K.R.; Keegan, D.M.; Ruoff, R.S.; Malhotra, R.M.

    1993-12-01

    Spatially resolved spectroscopic studies of a carbon arc operating under fullerene production conditions have been made across the visible wavelength range using an imaging Optical Multichannel Analyzer. C{sub 2} Swan bands are observed to be the major visible emissions although strong CI and CII as well as He I atomic lines are also observed. Video and photographic studies of the arc characteristics show the Swan-band emissions to be concentrated most intensely near the anode but also to appear strongly in regions well outside the electrode gap region. Vibrational and rotational temperatures of these bands provide information on the temperatures in various regions of the arc. The characteristic spatial structure of the arcs observed in the Swan-band light suggests that they are excited by electrons whose trajectories are controlled by the local electric and magnetic fields. The arc exhibits complex and interesting temporal behavior that has been observed with a video camera using short exposure times. Video film taken through a Swan-band filter clearly shows the dominant spatial features of the C{sub 2} emissions.

  3. Spectroscopic observations and analysis of the peculiar SN1999aa

    SciTech Connect

    Garavini, G.; Folatelli, G.; Goobar, A.; Nobili, S.; Aldering,G.; Amadon, A.; Amanullah, R.; Astier, P.; Balland, C.; Blanc, G.; Burns,M.S.; Conley, A.; Dahlen, T.; Deustua, S.E.; Ellis, R.; Fabbro, S.; Fan,X.; Frye, B.; Gates, E.L.; Gibbons, R.; Goldhaber, G.; Goldman, B.; Groom, D.E.; Haissinski, J.; Hardin, D.; Hook, I.M.; Howell, D.A.; Kasen,D.; Kent, S.; Kim, A.G.; Knop, R.A.; Lee, B.C.; Lidman, C.; Mendez, J.; Miller, G.J.; Moniez, M.; Mourao, A.; Newberg, H.; Nugent, P.E.; Pain,R.; Perdereau, O.; Perlmutter, S.; Prasad, V.; Quimby, R.; Raux, J.; Regnault, N.; Rich, J.; Richards, G.T.; Ruiz-Lapuente, P.; Sainton, G.; Schaefer, B.E.; Schahmaneche, K.; Smith, E.; Spadafora, A.L.; Stanishev,V.; Walton, N.A.; Wang, L.; Wood-Vasey, W.M.

    2003-12-10

    We present an extensive new time series of spectroscopic data of the peculiar SN 1999aa in NGC 2595. Our data set includes 25 optical spectra between -11 and +58 days with respect to B-band maximum light, providing an unusually complete time history. The early spectra resemble those of an SN 1991T-like object but with a relatively strong CaH and K absorption feature. The first clear sign of Si II lambda 6355, characteristic of Type Ia supernovae, is found at day -7, and its velocity remains constant up to at least the first month after B-band maximum light. The transition to normal-looking spectra is found to occur earlier than in SN 1991T, suggesting SN 1999aa as a possible link between SN 1991T-like and Branch-normal supernovae. Comparing the observations with synthetic spectra, doubly ionized Fe, Si, and Ni are identified at early epochs. These are characteristic of SN 1991 T-like objects. Furthermore, in the day -11 spectrum, evidence is found for an absorption feature that could be identified as high velocity C II lambda 6580 or H alpha. At the same epoch C III lambda 4648.8 at photospheric velocity is probably responsible for the absorption feature at 4500 8. High-velocity Ca is found around maximum light together with Si II and Fe II confined in a narrow velocity window. Implied constraints on supernovae progenitor systems and explosion hydrodynamic models are briefly discussed.

  4. Spectroscopic Observations of Propagating Disturbances in Polar Coronal Hole

    NASA Astrophysics Data System (ADS)

    Gupta, Girjesh R.; Marsch, Eckart; Solanki, Sami K.; Banerjee, Dipankar; Teriaca, Luca

    2012-07-01

    We focus on long duration spectroscopic observations of the south polar coronal hole taken on 1997 February 25 by the Solar Ultraviolet Measurements of Emitted Radiation (SUMER) spectrometer aboard SOHO. We analyze the data in the on-disk part of the coronal hole to find any signature of propagating waves or high speed up-flows. We find the clear presence of propagating disturbances in intensity and Doppler velocity with a projected propagation speed of about 60~km~s^{-1} and a periodicity of ≈14.5~min. During the propagation, the intensity enhancement is associated with a blue-shifted Doppler velocity. These disturbances are clearly seen in intensity at higher latitudes (i.e. closer to the limb), whereas disturbances in Doppler velocity becomes faint there. We study average spectral line profiles at the roots of these disturbances and along the propagating ridge. Based on our analysis, we interpret these disturbances in terms of propagating slow magneto-acoustic waves.

  5. LBT/LUCI Spectroscopic Observations of z≃7 Galaxies

    NASA Astrophysics Data System (ADS)

    Bian, Fuyan; Stark, Daniel P.; Fan, Xiaohui; Jiang, Linhua; Clément, Benjamin; Egami, Eiichi; Frye, Brenda; Green, Richard F.; McGreer, Ian D.; Cai, Zheng

    2015-06-01

    We present deep near-infrared spectroscopic observations of 13 luminous z≃ 7 Lyman break galaxies (LBGs) ({{M}UV}≃ -21) and a z≃ 9.6 lensed LBG candidate, MACS1149-JD1, using the LBT/LUCI spectrograph in the multi-object mode and long-slit mode, respectively. The z˜ 7 galaxies are selected in one of the Cosmic Assembly Near-infrared Deep Extragalactic Legacy Survey/WIDE survey observations, the UKIRT Infrared Deep Sky Survey Ultra Deep Survey field, and MACS1159-JD1 is selected from the Cluster Lensing And Supernova survey with Hubble survey observations. With ˜4-5 hr integrations, the LBT spectra are sensitive to Lyα emission, with rest-frame equivalent width greater than 55 Å (E{{W}0}\\gt 55 Å) at z˜ 7 and 90 Å (E{{W}0}\\gt 90 Å) at z˜ 9.5. No Lyα emission is observed in any of the z≃ 7 LBGs. After correcting the spectroscopic incompleteness, our measurements place an upper limit on the Lyα emission fraction of {{X}Lyα }(E{{W}0}\\gt 55 { {\\mathring{{A}} }},z≃ 7)\\lt 9.8% in luminous LBGs at z≃ 7. This result is consistent with the lack of Lyα emission in z\\gt 7 LBGs in previous studies. Together with other measurements of the Lyα emission fraction in LBGs at z≃ 7, this study puts a strong constraint on the fraction of luminous z≃ 7 LBGs with large EW Lyα, {{X}Lyα }(E{{W}0}\\gt 55 { {\\mathring{{A}} }},z≃ 7)=2.6-2.6+3.2%. We estimate the expected Lyα emission fraction at z≃ 7 by extrapolating the evolution of the fraction at low redshifts and find that the observed Lyα emission fraction is lower than the expected Lyα emission fraction at the 89% significance level, consistent with expectations if Lyα emission in z≃ 7 LBGs has been suppressed by neutral hydrogen in the intergalactic medium or optically thick absorbers around the galaxies. We do not find any strong Lyα emission feature at the redshift range of z ≃ 7.3-9.7 in the MACSJ1159-JD1 spectrum, either. This is consistent with the conclusion that Lyα emission in

  6. Spectroscopic Observations of the Star Formation Regions in Nearby Galaxies

    NASA Astrophysics Data System (ADS)

    Kong, X.; Lin, L.; Li, J. R.; Zhou, X.; Zou, H.; Li, H. Y.; Chen, F. Z.; Du, W.; Fan, Z.; Mao, Y. W.; Wang, J.; Zhu, Y. N.; Zhou, Z. M.

    2014-01-01

    During the late 1990s and the first decade of the 21st century, the 8˜10 m scale ground-based telescopes are helping astronomers learn much more about how galaxies develop. The existing 2˜4 m scale telescopes become less important for astrophysical researches. To use the existing 2˜4 m scale telescopes to address important issues in cosmology and extragalactic and galactic astronomy, we have to consider very carefully which kind of things we can do, and which we can not. For this reason, the Time Allocation Committee (TAC) of the National Astronomical Observatories of China (NAOC) 2.16 m telescope decides to support some key projects since 2013. Nearby galaxies supply us with the opportunity to study galaxy dynamics and star formation on large scales, yet are close enough to reveal the details. Star formation regions in nearby galaxies provide an excellent laboratory to study the star formation processes, the evolution of massive stars, and the properties of the surrounding interstellar medium. A wealth of information can be obtained from the spectral analysis of the bright emission lines and the stellar continuum. Considering these, we proposed a long-term project ``Spectroscopic Observations of the Star Formation Regions in Nearby Galaxies'', and it becomes the key project of the NAOC 2.16 m telescope since 2013, supported with 30 dark/grey nights per year. The primary goal of this project is to observe the spectroscopy of star formation regions in 20 nearby galaxies, with the NAOC 2.16 m telescope and the Hectospec/MMT (Multiple Mirror Telescope) multifiber spectrograph by Telescope Access Program (TAP). With the spectra of a large sample of star formation regions, combining multi-wavelength data from UV to IR, we can investigate, understand, and quantify the nature of the deviation from the starbursts' IRX-β (the IR/UV ratio ``IRX'' versus the UV color ``β'') correlation. It will be important for a better understanding of the interaction of dust and

  7. Using a Two-Stage Propensity Score Matching Strategy and Multilevel Modeling to Estimate Treatment Effects in a Multisite Observational Study

    ERIC Educational Resources Information Center

    Rickles, Jordan Harry

    2012-01-01

    In this study I present, demonstrate, and test a method that extends the Stuart and Rubin (2008) multiple control group matching strategy to a multisite setting. Three primary phases define the proposed method: (1) a design phase, in which one uses a two-stage matching strategy to construct treatment and control groups that are well balanced along…

  8. Statistical multisite simulations of summertime precipitation over South Korea and its future change based on observational data

    NASA Astrophysics Data System (ADS)

    Kim, Ji-Won; Kim, Kwang-Yul; Kim, Maeng-Ki; Cho, Chun-Ho; Lee, Youngjo; Lee, Jaeyong

    2013-11-01

    In this study, a weather generator for summer (May 19 - September 15) precipitation over South Korea is developed. Precipitation data for 33 years (1979-2011) observed at 57 stations of Korea Meteorological Administration (KMA) are used to develop a new weather generator. Using the cyclostationary empirical orthogonal function (CSEOF) technique, the observed precipitation data is described as a linear combination of deterministic evolution patterns and corresponding stochastic amplitude (principal component) time series. An autoregressive-moving average (ARMA) model is used to generate one hundred sets of synthetic amplitude time series for the period of 1979-2061 (83 years) with similar statistical properties of the original amplitude time series. Based on these synthetic time series and the annually repeating evolution patterns, one hundred sets of synthetic summer precipitation were generated. Statistical characteristics of the synthetic datasets are examined in comparison with those of the KMA observational record for the period of the observational record. Characteristic changes of synthetic precipitations for a future period are also examined. The seasonal cycle in the synthetic precipitation is reproduced faithfully with typical bimodal peaks of summer precipitation. The spatial correlation patterns of the synthetic precipitation are fairly similar to that of the observational data. The frequency-intensity relationship of the synthetic precipitation also looks similar to that of the observational data. In the future period, precipitation amount increases except in the precipitation range of (0,10) mm day-1 with nearly no change in the frequency of no-rain days; frequency increase is particularly conspicuous in the range of (100,500) mm day-1.

  9. Spectroscopic Observation of Chemical Interaction Between Impact-induced Vapor Clouds and the Ambient Atmosphere

    NASA Technical Reports Server (NTRS)

    Sugita, S.; Heineck, J. T.; Schultz, P. H.

    2000-01-01

    Chemical reactions within impact-induced vapor clouds were observed in laboratory experiments using a spectroscopic method. The results indicate that projectile-derived carbon-rich vapor reacts intensively with atmospheric nitrogen.

  10. Estimating CH4 and CO Emissions in California's Urban and Rural Regions Using Multi-site Observations

    NASA Astrophysics Data System (ADS)

    Jeong, S.; Andrews, A. E.; Bianco, L.; Graven, H. D.; Hsu, Y.; Newman, S.; Novakovskaia, E.; Vaca, P.; Salameh, P.; Sloop, C.; Weiss, R. F.; Keeling, R. F.; Fischer, M. L.

    2013-12-01

    California's commitment (Assembly Bill 32) to reduce total greenhouse gas (GHG) emissions to 1990 levels by 2020 (~20% reduction) requires quantification of current GHG emissions. We will present atmospheric inversion estimates of California's total CH4 emissions for summer 2013, using data from multiple sites covering urban and rural areas of California's South Coast Air Basin (SoCAB), Central Valley, and San Francisco Bay Area. We will also use measured CO from two tall-tower sites (Central Valley and SoCAB) to quantify CO emissions as well as to evaluate atmospheric transport. We use Bayesian inverse modeling to estimate the CH4 and CO emissions from discrete regions of California by combining the atmospheric measurements, upstream background, high-resolution prior emission maps, and predicted atmospheric transport from WRF-STILT. We quantify site-specific model-measurement uncertainties due to transport using meteorological data from a network of atmospheric profilers and in-situ sensors, due to background using oceanic and aircraft observations, and the prior emissions. To reduce the uncertainty in transport, we assimilate available meteorological measurements from surface and upper air stations, and wind profilers into the WRF model. Preliminary inversion results during September 2010 - June 2011 and summer of 2012 suggest that state total CH4 emissions are 1.2 - 1.8 times higher than the current CARB inventory and we will update these estimates. We expect the results of this study will significantly improve upon existing work in quantifying CH4 and CO emissions in California's urban and rural regions.

  11. Spectroscopic observations of X-ray selected late type stars

    NASA Technical Reports Server (NTRS)

    Takalo, L. O.

    1988-01-01

    A spectroscopic survey of nine X-ray selected late type stars was conducted. These stars are serendipitously discovered EINSTEIN X-ray sources, selected from two large x-ray surveys: the Columbia Astrophysical Laboratory survey (five stars) and the CFA Medium Sensitivity survey (four stars). Four of the Columbia survey stars were found to be short period binaries. The fifth was found to be an active single G dwarf. None of the Medium Sensitivity survey stars were found to be either binaries or active stars. Activity was measured by comparing the H-alpha and the CaII infrared triplet (8498, 8542) lines in these stars to the lines in inactive stars of similar spectral type. A correlation was found between the excess H-alpha lime emission and V sin(i) and between the excess H-alpha line emission and X-ray luminosity. No correlation was found between the infrared line emission and any other measured quantity.

  12. Spectroscopic and photometric observations of M supergiants in Carina.

    NASA Technical Reports Server (NTRS)

    Humphreys, R. M.; Strecker, D. W.; Ney, E. P.

    1972-01-01

    Spectroscopic study of 30 Southern-Hemisphere M supergiants mostly in Carina in the blue and near-infrared, and photometrical study of these stars from 0.4 to 18 microns. The uncertainties in the determinations of interstellar extinction are discussed, and the spatial distribution of the M supergiants in the Carina arm is shown. The presence of the 11-micron excess attributed to silicate dust is a common feature. Stars of the same spectral type and luminosity class are remarkably homogeneous in their long-wave behavior. The silicate feature becomes more prominent in the more luminous stars and in stars of later spectral type. Four composite systems show little long-wave excess. The two VV Cephei objects have excesses probably produced by gas emission, and the other two have little or no excess - supporting the suggestion that the presence of the early star prohibits the formation of a dust envelope. Three stars - VY CMa, VX Sgr, and HD 9767 - appear to be extreme examples of stars with large excesses over the entire long-wave region. It is suggested that these objects are surrounded by large amounts of particulate material over a great range of distances from the stars.

  13. NMR spectroscopic observation of a metal-free acetylide anion.

    PubMed

    Tanaka, Yoshiyuki; Arakawa, Makoto; Yamaguchi, Yohei; Hori, Chieko; Ueno, Masahiro; Tanaka, Takeyuki; Imahori, Tatsushi; Kondo, Yoshinori

    2006-10-20

    A metal-free acetylide was observed by using NMR spectroscopy. Metal-free acetylides are closely related to reactive intermediates (carbanions) in solution; therefore, they have been regarded as unobservable species. However, we generated this highly reactive and unstable species through the deprotonation of phenylacetylene by using the strong nonmetallic phosphazene base tBu-P4. In the presence of tBu-P4, the J coupling between the ethynyl carbon and hydrogen nuclei (1J(C,H)) of phenylacetylene disappeared; this indicates the deprotonation of the alkyne terminal. Furthermore, a large low-field shift (approximately 90 ppm) of the alkyne carbon resonance was observed. We concluded that we have observed a metal-free carbanion with a formal charge on an sp-hybridized carbon atom for the first time. PMID:17441096

  14. Herschel Spectroscopic Observations of Little Things Dwarf Galaxies

    NASA Astrophysics Data System (ADS)

    Cigan, Phil; Young, Lisa; Cormier, Diane; Lebouteiller, Vianney; Madden, Suzanne; Hunter, Deidre; Brinks, Elias; Elmegreen, Bruce; Schruba, Andreas; Heesen, Volker; the Little Things Team

    2016-01-01

    We present far-infrared (FIR) spectral line observations of five galaxies from the Little Things sample: DDO 69, DDO 70, DDO 75, DDO 155, and WLM. While most studies of dwarfs focus on bright systems or starbursts due to observational constraints, our data extend the observed parameter space into the regime of low surface brightness dwarf galaxies with low metallicities and moderate star formation rates. Our targets were observed with Herschel at the [C ii] 158 μm, [O i] 63 μm, [O iii] 88 μm, and [N ii] 122 μm emission lines using the PACS Spectrometer. These high-resolution maps allow us for the first time to study the FIR properties of these systems on the scales of larger star-forming complexes. The spatial resolution in our maps, in combination with star formation tracers, allows us to identify separate photodissociation regions (PDRs) in some of the regions we observed. Our systems have widespread [C ii] emission that is bright relative to continuum, averaging near 0.5% of the total infrared (TIR) budget—higher than in solar-metallicity galaxies of other types. [N ii] is weak, suggesting that the [C ii] emission in our galaxies comes mostly from PDRs instead of the diffuse ionized interstellar medium (ISM). These systems exhibit efficient cooling at low dust temperatures, as shown by ([O i]+[C ii])/TIR in relation to 60 μm/100 μm, and low [O i]/[C ii] ratios which indicate that [C ii] is the dominant coolant of the ISM. We observe [O iii]/[C ii] ratios in our galaxies that are lower than those published for other dwarfs, but similar to levels noted in spirals.

  15. Spectroscopic observation of nitrogen anions N(-) in solid matrices.

    PubMed

    Boltnev, R E; Bykhalo, I B; Krushinskaya, I N; Pelmenev, A A; Mao, S; Meraki, A; McColgan, P T; Lee, D M; Khmelenko, V V

    2016-06-21

    Analysis of old and recent experiments on thermoluminescence of cryocrystals and nanoclusters of N2, Ne, Ar, and Kr containing stabilized nitrogen atoms, suggests that the so-called γ-line may correspond to the bound-bound transition (1)D-(3)P of nitrogen anions N(-) formed in solids by the association of delocalized electrons and metastable nitrogen atoms N((2)D). The recent observations of the γ-line were accompanied by simultaneous luminescence of metastable nitrogen N((2)D) atoms and exoelectron emission. The fine structure of the γ-line at 793 nm has been experimentally observed and investigated for the first time. PMID:27241627

  16. Spectroscopic Observations of the 2011 Draconids Meteor Shower

    NASA Astrophysics Data System (ADS)

    Rudawska, Regina; Zender, Joe; Jenniskens, Peter; Vaubaillon, Jeremie; Koten, Pavel; Margonis, Anastasios; Tóth, Juraj; McAuliffe, Jonathan; Koschny, Detlef

    2014-08-01

    Some past October Draconid shower meteoroids fell apart in a spray of fragments at the end of their trajectory before slowing down, from which it was concluded that these were among the most fragile meteoroids known. In those instances, the dust could not be reliably traced to a particular return of the parent comet 21P/Giaconini-Zinner. On October 8th, 2011, Earth was predicted to transverse the 1900 A.D. dust ejecta of the comet. In 1900, the comet's perihelion distance first moved significantly inwards to the Sun and ejection conditions could have been unusual. An airborne observing campaign was organized, with several teams contributing imaging and spectrographic cameras to study the manner in which these meteoroids released the volatile element sodium during the ablation process in the Earth's atmosphere. IMCCE, ESA, and the SETI Institute contributed spectrographic cameras based on low-light WATEC 902H2 Ultimate, low-light LCC1, and GenII XX1332 image intensified cameras. An outburst was observed, much as predicted. Despite a lack of bright meteors, a total of 15 Draconid spectra were recorded. All show evidence of an early release of sodium. The loss of sodium was observed to coincide with the formation of a distinct wake of fragments. The observations show that 21P/Giacobini-Zinner ejected fragile meteoroids during the return in 1900. Those grains may have lost some sodium even before impacting Earth.

  17. SOHO/UVCS spectroscopic observations of coronal oscillations

    NASA Astrophysics Data System (ADS)

    Mancuso, Salvatore; Raymond, John C.; Rubinetti, Sara; Taricco, Carla

    2016-06-01

    We analyzed the temporal evolution of the intensities and Doppler shifts of two sets of high-cadence sit-and-stare observations acquired with the Ultraviolet Coronagraph Spectrometer (UVCS) on board the Solar and Heliospheric Observatory (SOHO) satellite to detect the possible signature of wave and oscillatory motions in the solar corona. The first set of data consisted of H I Lyα observations collected on 1997 December 14 at 1.43 RS above the eastern limb of the Sun. Spectral analysis of the data revealed clear Doppler-shift oscillations with period P = 14.3 min over a portion of the UVCS slit. The origin of these oscillations is attributable to the excitation of propagating fast-mode magnetoacoustic kink waves along a narrow, jet-like ejection observed higher up in the white-light corona. The second set of data consisted of O VI 1032 Å observations collected on 1996 December 19 at 1.38 RS above the north polar coronal hole. In this case, clear intensity oscillations (P = 19.5 min) and Doppler-shift oscillations (P = 7.2 min) over two different portions of the UVCS slit were detected. The origin of these oscillations is attributable to the excitation of slow-mode magnetoacoustic waves propagating along polar plumes that may partially account for heating of the plasma in the corona.

  18. Spectroscopic observations of D-type symbiotic stars

    NASA Astrophysics Data System (ADS)

    Pereira, C. B.; Landaberry, S. J. C.; Junqueira, S.

    1998-05-01

    Observations of five D-type symbiotics are presented: three oxygen Mira (He2-38, H2-38 and H1-36) and two carbon Mira symbiotics (AS 210 and SS 38). The observations in the spectral range between 3200Angstroms, and 7400Angstroms, show the presence of several emission lines in various states of excitation. A line list is provided with their suggested identifications. Several parameters were derived for each object: interstellar reddening as determined from Balmer decrement and Heii lines, temperature and electronic density, abundance ratios of Ne/O, Ar/O, Fe/Ne, N/O and He/H. We found nitrogen enrichment while for the other elements their abundances are compatible with solar, except iron which is depleted. We did not detect significant changes in the line and in the continuos spectra of the stars analyzed here, except for He2-38, which increased its degree of excitation compared to Allen's (1984) catalogue. Based on observations made with the 1.52m telescope at the European Southern Observatory (La Silla, Chile) under the agreement with the CNPq-Observatório Nacional (Brazil)

  19. Herschel FIR Spectroscopic Observations of L1448-MM

    NASA Astrophysics Data System (ADS)

    Lee, Jinhee; Lee, J.; DIGIT Team

    2012-01-01

    We present the FIR (continuum and line) maps and spectra of L1448-MM at 55 to 210 micron observed with the range scan mode of PACS on the Herschel Space Observatory, as part of the DIGIT key program. L1448-MM was previously known as an embedded Class 0 and prominent outflow source, and a secondary YSO was claimed by the Spitzer images and confirmed by submm interferometric observations. The PACS detected various CO, OH, H2O, and OI lines. The PACS line and continuum maps show that the emission at shorter wavelengths peaks at the central spatial pixel (the primary YSO position) although the line emission of low energy levels distributes along the outflow direction. According to our excitation analysis, the CO gas has two temperature components (warm and hot) that are tentatively attributed to PDR and shock, respectively. However, the H2O gas with the rotational temperature of 200 K seems to trace the shock. Interestingly, the relative strength of OH transitions suggests the IR pumping process dominates in L1448-MM. The gas along the outflow cavities in L1448-MM seems to be heated mainly by shock and UV photons, and relative line luminosities indicate that H2O and CO are the main coolants of this gas, although cooling by OI and OH cannot be ignored.

  20. Rotational Spectroscopic Studies and Observational Searches for HO3

    NASA Astrophysics Data System (ADS)

    Widicus Weaver, Susanna

    Interstellar chemistry is largely driven by reactions of unstable molecules that serve as reaction intermediates in terrestrial chemistry. One such class of compounds are weakly-bound clusters. These clusters could form in interstellar environments through radiative association reactions, but their identification and characterization in interstellar environments is limited by a lack of rotational spectral information. One such species is HO3, which could be formed in the interstellar medium from O2 and OH. HO3 has been studied extensively in the infrared, and there are a few microwave spectral studies that have also been reported. However, no millimeter or submillimeter spectral information is available to guide astronomical observations. In this talk, we will present the laboratory characterization of trans -HO3 and trans -DO3 from 70 to 450 GHz using our newly developed fast sweeping technique. The molecular constants have been significantly refined, and additional higher order centrifugal distortion constants have been determined. We will also present an initial observational search for HO3 in 32 star forming regions. Although no HO3 lines have been detected thus far, strict upper limits can be placed on the HO3 column density in these sources based on this analysis. Additional Authors: Luyao Zou, Brian M. Hays.

  1. Spectroscopic observations of the optical counterpart of Centaurus X-4

    NASA Technical Reports Server (NTRS)

    Van Paradijs, J.; Verbunt, F.; Van Der Linden, T.; Pedersen, H.; Wamsteker, W.

    1980-01-01

    The optical spectrum of the transient X-ray burst source Centaurus X-4 was observed about 5 weeks after the source reached its maximum. The brightness of the optical counterpart had decreased to V = 18.2, and the star had become appreciably redder (B - V = 0.7) compared to its color at maximum. The spectrum of Centaurus X-4 is similar to that of cataclysmic variables showing strong emission lines of H-1 and weaker lines of He-1 and He-2. The N03 lambda 4640 line is not visible. The continuum energy distribution of Centaurus X-4 shows the presence of a main-sequence star in the system, with spectral type between K3 and K7. This is consistent with the orbital period of 8.2 hr proposed by Kaluzienski et al (1980), if the main-sequence star is close to filling its Roche lobe.

  2. Spectroscopic observations of the symbiotic binary RW Hydrae

    NASA Technical Reports Server (NTRS)

    Kenyon, Scott J.; Fernandez-Castro, Telmo

    1987-01-01

    Ultraviolet/optical spectrophotometry and infrared photometry show that the symbiotic binary RW Hya is comprised of an M giant (with L of about 1000 solar luminosities) and a compact object (with L of about 200 solar luminosities) which resembles the central star of a planetary nebula. The luminosity of the hot component is produced by a nuclear shell source which is replenished by the wind of the red giant at a rate of about 10 to the -8th solar mass/yr. Results indicate that the binary is surrounded by an H II region (of radius of about 10 AU) which gives rise to the observed emission lines and radio emission. The He(2+) and O(2+) regions are found to be confined to the immediate vicinity of the hot component.

  3. Preliminary results of V440 Per and α UMi observations with the Poznan Spectroscopic Telescope

    NASA Astrophysics Data System (ADS)

    Fagas, M.; Baranowski, R.; Bartczak, P.; Borczyk, W.; Dimitrow, W.; Kaminski, K.; Kwiatkowski, T.; Ratajczak, R.; Rozek, A.; Schwarzenberg-Czerny, A.

    2009-03-01

    Presented herein are preliminary radial velocity results for two classical Cepheids: V440 Per and α UMi (Polaris). Both stars have been observed with the Poznan Spectroscopic Telescope (PST), operational since Aug 2007 at the Borowiec Station of Poznań Astronomical Observatory in Poland. Data obtained for V440 Per suggest the presence of a low-amplitude secondary mode of pulsations. Results of α UMi observations confirm further pulsation amplitude growth, as observed during the last decades.

  4. Spectroscopic observations of the detached binary PG 1413 + 015

    NASA Technical Reports Server (NTRS)

    Fulbright, Michael S.; Liebert, James; Bergeron, P.; Green, Richard

    1993-01-01

    We present improved estimates of the stellar parameters of the eclipsing, precataclysmic binary system PG 1413 + 015 (GH Vir), which has an orbital period of only 8h16m. Model atmosphere fits a Balmer line profiles yield T(eff) = 48,800 +/- 1200 K and log g = 7.70 +/- 0.11 for the DAO white dwarf primary star, from which a mass of 0.51 +/- 0.04 solar mass is inferred using evolutionary models. An ultraviolet spectrum obtained with the IUE Observatory has a slope consistent with this temperature and the assumption of no interstellar extinction. A red CCD spectrum of the secondary star during the 12-minute total eclipse indicates a spectral type of M3 V-M5 V. Reanalysis of the eclipse light curve leads to an inferred radius of 0.15 solar radius and a mass of 0.10 solar mass for the secondary, the latter being marginally consistent with the spectral type. Reprocessing on the facing side of the secondary produces phase-dependent Balmer line emission and detectable variations in the continuum from 6500-9000 A. The observed levels of reprocessing are consistent with expectations based on the above stellar parameters.

  5. Spitzer mid-infrared spectroscopic observations of planetary nebulae

    NASA Astrophysics Data System (ADS)

    Mata, H.; Ramos-Larios, G.; Guerrero, M. A.; Nigoche-Netro, A.; Toalá, J. A.; Fang, X.; Rubio, G.; Kemp, S. N.; Navarro, S. G.; Corral, L. J.

    2016-06-01

    We present Spitzer Space Telescope archival mid-infrared (mid-IR) spectroscopy of a sample of 11 planetary nebulae (PNe). The observations, acquired with the Spitzer Infrared Spectrograph (IRS), cover the spectral range 5.2-14.5 μm that includes the H2 0-0 S(2) to S(7) rotational emission lines. This wavelength coverage has allowed us to derive the Boltzmann distribution and calculate the H2 rotational excitation temperature (Tex). The derived excitation temperatures have consistent values ≃900 ± 70 K for different sources despite their different structural components. We also report the detection of mid-IR ionic lines of [Ar III], [S IV], and [Ne II] in most objects, and polycyclic aromatic hydrocarbon features in a few cases. The decline of the [Ar III]/[Ne II] line ratio with the stellar effective temperature can be explained either by a true neon enrichment or by high density circumstellar regions of PNe that presumably descend from higher mass progenitor stars.

  6. Spectroscopic observations of low-lying gas clouds: sensitivity of detection by method of covariance matrix

    NASA Astrophysics Data System (ADS)

    Margolis, Jack S.; Liu, Karen Y.; Moynihan, Philip I.

    1999-01-01

    The sensitivity of spectroscopic detection of low-lying gas clouds by an arbitrary spectrometer may be determined by simulating the observation using a high spectral resolution radiative transfer code. The instrumental characteristics may be superimposed on the simulation and the accuracy of the retrieval of the desired parameters may be estimated by use of the covariance matrix.

  7. Photoelectric and Spectroscopic Observations Related to a Possible Optical Counterpart for Pulsar CP 1919+21.

    PubMed

    Lynds, R; Maran, S P; Trumbo, D E

    1968-07-01

    Spectroscopic observations of the two stars near the pulsar CP 1919+21 are not sufficiently conclusive to permit an identification of either object with the source of the radio pulses. However, our most extensive series of photometric observations of a region of sky near the radio source position, which region includes the brighter of the two stars, suggests an approximately sinusoidal variation. It is significant that the period of the variation is double the period of the radio pulsations. PMID:17756510

  8. Optical Spectroscopic Observations of Gamma-Ray Blazar Candidates. VI. Further Observations from TNG, WHT, OAN, SOAR, and Magellan Telescopes

    NASA Astrophysics Data System (ADS)

    Álvarez Crespo, N.; Massaro, F.; Milisavljevic, D.; Landoni, M.; Chavushyan, V.; Patiño-Álvarez, V.; Masetti, N.; Jiménez-Bailón, E.; Strader, J.; Chomiuk, L.; Katagiri, H.; Kagaya, M.; Cheung, C. C.; Paggi, A.; D'Abrusco, R.; Ricci, F.; La Franca, F.; Smith, Howard A.; Tosti, G.

    2016-04-01

    Blazars, one of the most extreme classes of active galaxies, constitute so far the largest known population of γ-ray sources, and their number is continuously growing in the Fermi catalogs. However, in the latest release of the Fermi catalog there is still a large fraction of sources that are classified as blazar candidates of uncertain type (BCUs) for which optical spectroscopic observations are necessary to confirm their nature and their associations. In addition, about one-third of the γ-ray point sources listed in the Third Fermi-LAT Source Catalog (3FGL) are still unassociated and lacking an assigned lower-energy counterpart. Since 2012 we have been carrying out an optical spectroscopic campaign to observe blazar candidates to confirm their nature. In this paper, the sixth of the series, we present optical spectroscopic observations for 30 γ-ray blazar candidates from different observing programs we carried out with the Telescopio Nazionale Galileo, William Herschel Telescope, Observatorio Astronómico Nacional, Southern Astrophysical Research Telescope, and Magellan Telescopes. We found that 21 out of 30 sources investigated are BL Lac objects, while the remaining targets are classified as flat-spectrum radio quasars showing the typical broad emission lines of normal quasi-stellar objects. We conclude that our selection of γ-ray blazar candidates based on their multifrequency properties continues to be a successful way to discover potential low-energy counterparts of the Fermi unidentified gamma-ray sources and to confirm the nature of BCUs.

  9. Massive Young Stellar Objects in the Galactic Center. 1; Spectroscopic Identification from Spitzer/IRS Observations

    NASA Technical Reports Server (NTRS)

    An, Deokkeun; Ramirez, Solange V.; Sellgren, Kris; Arendt, Richard G.; Boogert, A. C. Adwin; Robitaille, Thomas P.; Schultheis, Mathias; Cotera, Angela S.; Smith, Howard A.; Stolovy, Susan R.

    2011-01-01

    We present results from our spectroscopic study, using the Infrared Spectrograph (IRS) onboard the Spitzer Space Telescope, designed to identify massive young stellar objects (YSOs) in the Galactic Center (GC). Our sample of 107 YSO candidates was selected based on IRAC colors from the high spatial resolution, high sensitivity Spitzer/IRAC images in the Central Molecular Zone (CMZ), which spans the central approximately 300 pc region of the Milky Way Galaxy. We obtained IRS spectra over 5 micron to 35 micron using both high- and low-resolution IRS modules. We spectroscopically identify massive YSOs by the presence of a 15.4 micron shoulder on the absorption profile of 15 micron CO2 ice, suggestive of CO2 ice mixed with CH30H ice on grains. This 15.4 micron shoulder is clearly observed in 16 sources and possibly observed in an additional 19 sources. We show that 9 massive YSOs also reveal molecular gas-phase absorption from C02, C2H2, and/or HCN, which traces warm and dense gas in YSOs. Our results provide the first spectroscopic census of the massive YSO population in the GC. We fit YSO models to the observed spectral energy distributions and find YSO masses of 8 - 23 solar Mass, which generally agree with the masses derived from observed radio continuum emission. We find that about 50% of photometrically identified YSOs are confirmed with our spectroscopic study. This implies a preliminary star formation rate of approximately 0.07 solar mass/yr at the GC.

  10. MASSIVE YOUNG STELLAR OBJECTS IN THE GALACTIC CENTER. I. SPECTROSCOPIC IDENTIFICATION FROM SPITZER INFRARED SPECTROGRAPH OBSERVATIONS

    SciTech Connect

    An, Deokkeun; RamIrez, Solange V.; Boogert, A. C. Adwin; Sellgren, Kris; Arendt, Richard G.; Schultheis, Mathias; Cotera, Angela S.; Stolovy, Susan R.

    2011-08-01

    We present results from our spectroscopic study, using the Infrared Spectrograph (IRS) on board the Spitzer Space Telescope, designed to identify massive young stellar objects (YSOs) in the Galactic center (GC). Our sample of 107 YSO candidates was selected based on Infrared Array Camera (IRAC) colors from the high spatial resolution, high sensitivity Spitzer/IRAC images in the Central Molecular Zone, which spans the central {approx}300 pc region of the Milky Way. We obtained IRS spectra over 5-35 {mu}m using both high- and low-resolution IRS modules. We spectroscopically identify massive YSOs by the presence of a 15.4 {mu}m shoulder on the absorption profile of 15 {mu}m CO{sub 2} ice, suggestive of CO{sub 2} ice mixed with CH{sub 3}OH ice on grains. This 15.4 {mu}m shoulder is clearly observed in 16 sources and possibly observed in an additional 19 sources. We show that nine massive YSOs also reveal molecular gas-phase absorption from CO{sub 2}, C{sub 2}H{sub 2}, and/or HCN, which traces warm and dense gas in YSOs. Our results provide the first spectroscopic census of the massive YSO population in the GC. We fit YSO models to the observed spectral energy distributions and find YSO masses of 8-23 M{sub sun}, which generally agree with the masses derived from observed radio continuum emission. We find that about 50% of photometrically identified YSOs are confirmed with our spectroscopic study. This implies a preliminary star formation rate of {approx}0.07 M{sub sun} yr{sup -1} at the GC.

  11. The source regions of the solar wind revealed by UV/EUV spectroscopic observations

    NASA Astrophysics Data System (ADS)

    Xia, L.

    2012-06-01

    The heating of the solar corona and the origin and acceleration of the solar wind are among the important unsolved problems of space plasma and solar physics. During the SOHO era, coronal holes as source regions of the fast solar wind have been investigated by using UV/EUV spectroscopic data observed with high-resolution spectrometers. At the base of the coronal hole, a detailed picture concerning the origin of the fast solar wind was first obtained by SUMER observations. For example, the Dopplergram deduced from the line profile of Ne VIII and other transition-region lines showed strong evidence that the wind originates in the chromospheric network and starts flowing out of the corona in magnetic funnels. Solar wind mass is suggested to be supplied through supergranule-scale magnetoconvection in the chromosphere and transition region. However, the spectral lines used in these studies are mainly obtained in the transition region and the behaviours of the nascent solar wind at higher temperatures have not yet been understood. Recent spectroscopic and imaging observations with instruments on Hinode and SDO provide further information about the coronal holes seen in EUV lines formed in the solar corona. Some interesting results, e.g., ubiquitous episodic outflow (jets) and enhanced emission in the blue wing of coronal line profiles, are found from the new observations. The purpose of this presentation is to review recent research progress on solar-wind source regions revealed by UV/EUV spectroscopic and imaging observations. Such observational studies and further interpretations of the data may provide crucial constraints and implications for future studies on both observations and theoretical models concerning coronal heating and acceleration of the nascent solar wind.

  12. Spectroscopic and photometric observations of the M31 nova candidate PTF12ahb

    NASA Astrophysics Data System (ADS)

    Shafter, A. W.; Darnley, M. J.; Bode, M. F.; Ciardullo, R.; Hornoch, K.; Cao, Y.; Kasliwal, M. M.

    2012-02-01

    We report spectroscopic and photometric observations of the M31 nova candidate PTF12ahb (tentatively designated M31N 2012-02a) discovered by Cao et al. (ATel #3905) on 2012 Feb 01.117 UT at R = 19.1. At our request, a spectrum (410-900 nm) was obtained by J. Caldwell on 2012 Feb. 03.08 UT with the 9.2m Hobby-Eberly Telescope (+ Marcario Low-Resolution Spectrograph). The spectrum reveals narrow (marginally resolved) Balmer and Fe II emission lines (FWHM Hα ~ 600 km/s; EW Hα ~ -9.0 nm) superimposed on a slightly blue continuum.

  13. Spectroscopic observations of the counterpart of IGR J00291+5934

    NASA Astrophysics Data System (ADS)

    Roelofs, G.; Jonker, P. G.; Steeghs, D.; Torres, M.; Nelemans, G.

    2004-12-01

    Spectroscopic observations of the optical counterpart of the millisecond X-ray pulsar IGR J00291+5934 (Atel #352, 353) reported in an Atel by Fox & Kulkarni were obtained (Dec 5 00:29-01:15 UT) with the ISIS spectrograph mounted on the 4.2m William Herschel Telescope on La Palma. Weather conditions were not optimal with a seeing of ~2" and thin clouds. The spectra show weak evidence for broad emission line features near the HeII line at 4686 Angstrom and near the Halpha line at 6563 Angstrom.

  14. Clinical Utility of an Observation and Response Chart With Human Factors Design Characteristics and a Track and Trigger System: Study Protocol for a Two-Phase Multisite Multiple-Methods Design

    PubMed Central

    McKinley, Sharon; Perry, Lin; Duffield, Christine; Iedema, Rick; Gallagher, Robyn; Fry, Margaret; Roche, Michael; Allen, Emily

    2014-01-01

    Background Clinical deterioration of adult patients in acute medical-surgical wards continues to occur, despite a range of systems and processes designed to minimize this risk. In Australia, a standardized template for adult observation charts using human factors design principles and decision-support characteristics was developed to improve the detection of and response to abnormal vital signs. Objective To describe the study protocol for the clinical testing of these observation and response charts (ORCs). Methods We propose a two-phase multisite multiple-methods design to test the initial clinical utility of the charts in 10 hospitals of differing types and sizes across state jurisdictions in Australia. Data collection in the first phase includes user surveys, observations and field notes by project officers, handover de-briefs (short interviews with small groups of staff), and an audit of ORC documentation completion compared to the site’s existing observation chart. For the second phase, data will be collected using a retrospective audit of observation documentation from the previous hospital observation chart, prospective audit of observation documentation following implementation of the selected ORC, user focus groups, observational field notes, and patient outcome data from routinely collected organizational data sources. Results Site selection and preparation, project officer training, chart selection and implementation, participant recruitment, and data collection has been completed and the analysis of these results are in progress. Conclusions This detailed description of these study methods and data collection approaches will enable a comprehensive assessment of the clinical utility of these newly developed track and trigger charts and will be useful for clinicians and researchers when planning and implementing similar studies. Potential methodological limitations are also noted. PMID:25116446

  15. Low X-Ray Luminosity Galaxy Clusters: Main Goals, Sample Selection, Photometric and Spectroscopic Observations

    NASA Astrophysics Data System (ADS)

    Nilo Castellón, José Luis; Alonso, M. Victoria; García Lambas, Diego; Valotto, Carlos; O’ Mill, Ana Laura; Cuevas, Héctor; Carrasco, Eleazar R.; Ramírez, Amelia; Astudillo, José M.; Ramos, Felipe; Jaque Arancibia, Marcelo; Ulloa, Natalie; Órdenes, Yasna

    2016-06-01

    We present our study of 19 low X-ray luminosity galaxy clusters (L{}X ∼ 0.5–45 × 1043 erg s‑1), selected from the ROSAT Position Sensitive Proportional Counters Pointed Observations and the revised version of Mullis et al. in the redshift range of 0.16–0.7. This is the introductory paper of a series presenting the sample selection, photometric and spectroscopic observations, and data reduction. Photometric data in different passbands were taken for eight galaxy clusters at Las Campanas Observatory; three clusters at Cerro Tololo Interamerican Observatory; and eight clusters at the Gemini Observatory. Spectroscopic data were collected for only four galaxy clusters using Gemini telescopes. Using the photometry, the galaxies were defined based on the star-galaxy separation taking into account photometric parameters. For each galaxy cluster, the catalogs contain the point-spread function and aperture magnitudes of galaxies within the 90% completeness limit. They are used together with structural parameters to study the galaxy morphology and to estimate photometric redshifts. With the spectroscopy, the derived galaxy velocity dispersion of our clusters ranged from 507 km s‑1 for [VMF98]022 to 775 km s‑1 for [VMF98]097 with signs of substructure. Cluster membership has been extensively discussed taking into account spectroscopic and photometric redshift estimates. In this sense, members are the galaxies within a projected radius of 0.75 Mpc from the X-ray emission peak and with clustercentric velocities smaller than the cluster velocity dispersion or 6000 km s‑1, respectively. These results will be used in forthcoming papers to study, among the main topics, the red cluster sequence, blue cloud and green populations, the galaxy luminosity function, and cluster dynamics.

  16. Near-Infrared Spectroscopic Study of AA Tau: Water and OH Observations

    NASA Astrophysics Data System (ADS)

    Brown, Logan Ryan; Gibb, Erika

    2014-06-01

    To understand our own solar origins, we must investigate the composition of the protoplanetary disk from which the solar system formed. To infer this, we study analogs to the early solar system called T Tauri stars. These objects are low-mass, pre-main sequence stars surrounded by circumstellar disks of material from which planets are believed to form. We present high-resolution (λ/Δλ˜25,000), near-infrared spectroscopic data from the T Tauri star AA Tau using NIRSPEC at the Keck II telescope, located on Mauna Kea, HI, taken in 2009 and 2010. AA Tau has a close to edge-on geometry, with an inclination of 70° ± 10° (Donati et al. 2010). Objects must have a nearly edge-on inclination for the disk to be sampled via absorption line spectroscopy. We observed strong absorption lines of both water and OH to which a spectroscopic model was fit in order for us to determine column density and rotational temperature. These near-infrared observations complement the work being done with ALMA, allowing us to probe the inner most disk regions and the chemistry contained within while ALMA primarily samples and is most sensitive to the outer disk.

  17. Chemical Nature Of Titan’s Organic Aerosols Constrained from Spectroscopic and Mass Spectrometric Observations

    NASA Astrophysics Data System (ADS)

    Imanaka, Hiroshi; Cruikshank, D. P.

    2012-10-01

    The Cassini-Huygens observations greately extend our knowledge about Titan’s organic aerosols. The Cassini INMS and CAPS observations clearly demonstrate the formation of large organic molecules in the ionosphere [1, 2]. The VIMS and CIRS instruments have revealed spectral features of the haze covering the mid-IR and far-IR wavelengths [3, 4, 5, 6]. This study attempts to speculate the possible chemical nature of Titan’s aerosols by comparing the currently available observations with our laboratory study. We have conducted a series of cold plasma experiment to investigate the mass spectrometric and spectroscopic properties of laboratory aerosol analogs [7, 8]. Titan tholins and C2H2 plasma polymer are generated with cold plasma irradiations of N2/CH4 and C2H2, respectively. Laser desorption mass spectrum of the C2H2 plasma polymer shows a reasonable match with the CAPS positive ion mass spectrum. Furthermore, spectroscopic features of the the C2H2 plasma polymer in mid-IR and far-IR wavelegths qualitatively show reasonable match with the VIMS and CIRS observations. These results support that the C2H2 plasma polymer is a good candidate material for Titan’s aerosol particles at the altitudes sampled by the observations. We acknowledge funding supports from the NASA Cassini Data Analysis Program, NNX10AF08G, and from the NASA Exobiology Program, NNX09AM95G, and the Cassini Project. [1] Waite et al. (2007) Science 316, 870-875. [2] Crary et al. (2009) Planet. Space Sci. 57, 1847-1856. [3] Bellucci et al. (2009) Icarus 201, 198-216. [4] Anderson and Samuelson (2011) Icarus 212, 762-778. [5] Vinatier et al. (2010) Icarus 210, 852-866. [6] Vinatier et al. (2012) Icarus 219, 5-12. [7] Imanaka et al. (2004) Icarus 168, 344-366. [8] Imanaka et al. (2012) Icarus 218, 247-261.

  18. Direct Spectroscopic Observation of a Shallow Hydrogenlike Donor State in Insulating SrTiO3

    NASA Astrophysics Data System (ADS)

    Salman, Z.; Prokscha, T.; Amato, A.; Morenzoni, E.; Scheuermann, R.; Sedlak, K.; Suter, A.

    2014-10-01

    We present a direct spectroscopic observation of a shallow hydrogenlike muonium state in SrTiO3 which confirms the theoretical prediction that interstitial hydrogen may act as a shallow donor in this material. The formation of this muonium state is temperature dependent and appears below ˜70 K. From the temperature dependence we estimate an activation energy of ˜50 meV in the bulk and ˜23 meV near the free surface. The field and directional dependence of the muonium precession frequencies further supports the shallow impurity state with a rare example of a fully anisotropic hyperfine tensor. From these measurements we determine the strength of the hyperfine interaction and propose that the muon occupies an interstitial site near the face of the oxygen octahedron in SrTiO3. The observed shallow donor state provides new insight for tailoring the electronic and optical properties of SrTiO3-based oxide interface systems.

  19. High-Resolution Spectroscopic Database for the NASA Earth Observing System Program

    NASA Technical Reports Server (NTRS)

    Rothman, Laurence S.; Starr, David (Technical Monitor)

    2002-01-01

    The purpose of this project is to develop and enhance the HITRAN molecular spectroscopic database and associated software to support the observational programs of the Earth Observing System (EOS). In particular, the focus is on the EOS projects: the Atmospheric Infrared Sounder (AIRS), the High-Resolution Dynamics Limb Sounder (HIRDLS), Measurements of Pollution in the Troposphere (MOPITT), the Tropospheric Emission Spectrometer (TES), and the Stratospheric Aerosol and Gas Experiment (SAGE III). The data requirements of these programs in terms of spectroscopy are varied, but usually call for additional spectral parameters or improvements to existing molecular bands. In addition, cross-section data for heavier molecular species must be expanded and made amenable to modeling in remote sensing. The effort in the project also includes developing software and distribution to make access, manipulation, and use of HITRAN functional to the EOS program.

  20. Optical spectroscopic observations of γ-ray blazar candidates. I. Preliminary results

    SciTech Connect

    Paggi, A.; Milisavljevic, D.; D'Abrusco, R.; Smith, H. A.; Margutti, R.; Martínez-Galarza, J. R.; Landoni, M.; Grindlay, J. E.; Masetti, N.; Giroletti, M.; Jiménez-Bailón, E.; Otí-Floranes, H.; Chavushyan, V.; Massaro, F.; Funk, S.; Tosti, G.

    2014-05-01

    A significant fraction (∼30%) of the γ-ray sources listed in the second Fermi/LAT (2FGL) catalog is still of unknown origin, being not yet associated with counterparts at lower energies. Using the available information at lower energies and optical spectroscopy on the selected counterparts of these γ-ray objects, we can pinpoint their exact nature. Here, we present a pilot project pointing to assess the effectiveness of the several classification methods developed to select γ-ray blazar candidates. To this end, we report optical spectroscopic observations of a sample of five γ-ray blazar candidates selected on the basis of their infrared Wide-field Infrared Survey Explorer (WISE) colors or of their low-frequency radio properties. Blazars come in two main classes, BL Lac objects and FSRQs, showing similar optical spectra except for the stronger emission lines of the latter. For three of our sources, the almost featureless optical spectra obtained confirm their BL Lac nature, while for the source WISEJ022051.24+250927.6 we observe emission lines with equivalent width EW ∼ 31 Å, identifying it as a FSRQ with z = 0.48. The source WISEJ064459.38+603131.7, although not featuring a clear radio counterpart, shows a blazar-like spectrum with weak emission lines with EW ∼ 7 Å, yielding a redshift estimate of z = 0.36. In addition, we report optical spectroscopic observations of four WISE sources associated with known γ-ray blazars without a firm classification or redshift estimate. For the latter sources, we confirm a BL Lac classification, with a tentative redshift estimate for the source WISEJ100800.81+062121.2 of z = 0.65.

  1. Submillimetric spectroscopic observations of volatiles in comet C/2004 Q2 (Machholz)

    NASA Astrophysics Data System (ADS)

    de Val-Borro, M.; Hartogh, P.; Jarchow, C.; Rengel, M.; Villanueva, G. L.; Küppers, M.; Biver, N.; Bockelée-Morvan, D.; Crovisier, J.

    2012-09-01

    Context. Submillimeter spectroscopic observations of comets provide an important tool for understanding their chemical composition and enable a taxonomic classification. Aims: We aim to determine the production rates of several parent- and product volatiles and the 12C/13C isotopic carbon ratio in the long-period comet C/2004 Q2 (Machholz), which is likely to originate from the Oort Cloud. Methods: The line emission from several molecules in the coma was measured with high signal-to-noise ratio in January 2005 at heliocentric distance of 1.2 AU by means of high-resolution spectroscopic observations using the Submillimeter Telescope (SMT) at the Arizona Radio Observatory (ARO). Results: We have obtained production rates of several volatiles (CH3OH, HCN, H13CN, HNC, H2CO, CO, and CS) by comparing the observed and simulated line-integrated intensities. We calculated the synthetic profiles using a radiative transfer code that includes collisions between neutrals and electrons, and the effects of radiative pumping of the fundamental vibrational levels by solar infrared radiation. Furthermore, multiline observations of the CH3OH J = 7-6 series allow us to estimate the rotational temperature using the rotation diagram technique. We find that the CH3OH population distribution of the levels sampled by these lines can be described by a rotational temperature of 40 ± 3 K. Derived mixing ratios relative to hydrogen cyanide are CO/CH3OH/H2CO/CS/HNC/H13CN/HCN = 30.9/24.6/4.8/0.57/0.031/0.013/1 assuming a pointing offset of 8'' due to the uncertain ephemeris at the time of the observations and the telescope pointing error. Conclusions: The measured relative molecular abundances in C/2004 Q2 (Machholz) are between low- to typical values of those obtained in Oort Cloud comets, suggesting that it has visited the inner solar system previously and undergone thermal processing. The HNC/HCN abundance ratio of ~3.1% is comparable to that found in other comets, accounting for the

  2. Vibrational Spectroscopic Observation of Atomic-Scale Local Surface Sites Using Site-Selective Signal Enhancement.

    PubMed

    Hu, Jian; Hoshi, Nagahiro; Uosaki, Kohei; Ikeda, Katsuyoshi

    2015-12-01

    Molecule-substrate interactions are sensitively affected by atomic-scale surface structures. Unique activity in heterogeneous catalysts or electrocatalysts is often related with local surface sites with specific structures. We demonstrate that adsorption geometry of a model molecule with an isocyanide anchor is drastically varied among one-fold atop, two-fold bridge, and three-fold hollow configurations with increasing the size of atomic-scale local surface sites of Pd islands on an Au(111) model surface. The vibrational spectroscopic observation of such local information is realized by site-selective and self-assembled formation of hotspots, where Raman scattering intensity is significantly enhanced via excitation of localized surface plasmons. PMID:26551000

  3. Implementation of Multiple Spectroscopic Techniques to Simultaneously Observe Native and Mutated Protein Unfolding

    NASA Astrophysics Data System (ADS)

    Cull, Brennan; Ben, Kelty; Link, Justin

    A protein's natural, correctly folded structure can determine the protein's ability to carry out its function. If the unfolding process of proteins can be observed, then the relative stability can be better understood between native and mutated proteins. A global picture of the unfolding process may be completed through the studies of strategically mutated proteins using tryptophan as a probe. Horse heart cytochrome c, a thoroughly studied, model protein was used in our investigation to explore this idea. Various spectroscopic techniques such as circular dichroism (CD), absorbance, and fluorescence were simultaneously applied while slowly unfolding our protein by increasing the concentration of a chemical denaturant, guanidine hydrochloride. This provided us information about the thermodynamic properties of the protein and several mutants which can then be interpreted to gain relative stability information among mutations. Efforts to utilize these techniques on native and mutated proteins in comparison to current scientific unfolding theories will be presented in this session.

  4. Photometric Observations of the η Carinae 2009.0 Spectroscopic Event

    NASA Astrophysics Data System (ADS)

    Landes, H.; Fitzgerald, M.

    2010-09-01

    We have observed η Carinae over 34 nights between 2009 January 4 and 2009 March 27 covering the estimated timeframe for a predicted spectroscopic event related to a suspected binary system concealed within the homunculus nebula. A photometric minimum feature was confirmed to be periodic and comparison to a previous event indicated that the period to within our error was 2022.6+/-1.0d. Using the E-region standard star system, the apparent V magnitudes determined for the local comparison stars were HD 303308 8.14+/-0.02, HD 93205 7.77+/-0.03, and HD 93162 8.22+/-0.05. The latter star was found to be dimmer than previously reported.

  5. High-dispersion infrared spectroscopic observations of comet 8P/Tuttle with VLT/CRIRES

    NASA Astrophysics Data System (ADS)

    Kobayashi, H.; Bockelée-Morvan, D.; Kawakita, H.; Dello Russo, N.; Jehin, E.; Manfroid, J.; Smette, A.; Hutsemékers, D.; Stüwe, J.; Weiler, M.; Arpigny, C.; Biver, N.; Cochran, A.; Crovisier, J.; Magain, P.; Sana, H.; Schulz, R.; Vervack, R. J.; Weaver, H.; Zucconi, J.-M.

    2010-01-01

    We report on the composition of the Halley-family comet (HFC) 8P/Tuttle investigated with high-dispersion near-infrared spectroscopic observations. The observations were carried out at the ESO VLT (Very Large Telescope) with the CRIRES instrument as part of a multi-wavelength observation campaign of 8P/Tuttle performed in late January and early February 2008. Radar observations suggested that 8P/Tuttle is a contact binary, and it was proposed that these components might be heterogeneous in chemistry. We determined mixing ratios of organic volatiles with respect to H2O and found that mixing ratios were consistent with previous near infrared spectroscopic observations obtained in late December 2007 and in late January 2008. It has been suggested that because 8P/Tuttle is a contact binary, it might be chemically heterogeneous. However, we find no evidence for chemical heterogeneity within the nucleus of 8P/Tuttle. We also compared the mixing ratios of organic molecules in 8P/Tuttle with those of both other HFCs and long period comets (LPCs) and found that HCN, C2H2, and C2H6 are depleted whereas CH4 and CH3OH have normal abundances. This may indicate that 8P/Tuttle was formed in a different region of the early solar nebula than other HFCs and LPCs. We estimated the conversion efficiency from C2H2 to C2H6 by hydrogen addition reactions on cold grains by employing the C2H6/(C2H6+C2H2) ratio. The C2H6/(C2H6+C2H2) ratio in 8P/Tuttle is consistent with the ratios found in other HFCs and LPCs within the error bars. We also discuss the source of C2 and CN based on our observations and conclude that the abundances of C2H2 and C2H6 are insufficient to explain the C2 abundances in comet 8P/Tuttle and that the abundance of HCN is insufficient to explain the CN abundances in the comet, so at least one additional parent is needed for each species, as pointed out in previous study. Based on observations collected at the European Southern Observatory, Paranal, Chile (ESO Prog. 080.C

  6. Submillimetric Spectroscopic Observations of Volatiles in Comet C-2004 Q2 (Machholz)

    NASA Technical Reports Server (NTRS)

    DeVal-Borro, M.; Hartogh, P.; Jarchow, C.; Rengel, M.; Villanueva, G. L.; Kueppers, M.; Biver, N.; Bockelee-Morvan, D.; Crovisier, J.

    2012-01-01

    Submillimeter spectroscopic observations of comets provide an important tool for understanding their chemical composition and enable a taxonomic classification. Aims. We aim to determine the production rates of several parent- and product volatiles and the C-12/C-13 isotopic carbon ratio in the long-period comet C/2004 Q2 (Machholz), which is likely to originate from the Oort Cloud. Methods. The line emission from several molecules in the coma was measured with high signal-to-noise ratio in January 2005 at heliocentric distance of 1.2 AU by means of high-resolution spectroscopic observations using the Submillimeter Telescope (SMT) at the Arizona Radio Observatory (ARO). Results. We have obtained production rates of several volatiles (CH3OH, HCN, H(sup 13)CN, HNC, H2CO, CO, and CS) by comparing the observed and simulated line-integrated intensities. We calculated the synthetic profiles using a radiative transfer code that includes collisions between neutrals and electrons, and the effects of radiative pumping of the fundamental vibrational levels by solar infrared radiation. Furthermore, multiline observations of the CH3OH J = 7-6 series allow us to estimate the rotational temperature using the rotation diagram technique. We find that the CH3OH population distribution of the levels sampled by these lines can be described by a rotational temperature of 40 +/- 3 K. Derived mixing ratios relative to hydrogen cyanide are CO/CH3OH/H2CO/CS/HNC/HC-13N/HCN= 30.9/24.6/4.8/0.57/0.031/0.013/1 assuming a pointing offset of 8" due to the uncertain ephemeris at the time of the observations and the telescope pointing error. Conclusions. The measured relative molecular abundances in C/2004 Q2 (Machholz) are between low- to typical values of those obtained in Oort Cloud comets, suggesting that it has visited the inner solar system previously and undergone thermal processing. The HNC/HCN abundance ratio of approx 3.1% is comparable to that found in other comets, accounting for the

  7. High-Resolution Spectroscopic Database for the NASA Earth Observing System Program

    NASA Technical Reports Server (NTRS)

    Rothman, Laurence

    2003-01-01

    The purpose of this project is to develop and enhance the HITRAN molecular spectroscopic database and associated software to support the observational programs of the Earth Observing System (EOS). In particular, the focus is on the EOS projects: the Atmospheric Infrared Sounder (AIRS), the High-Resolution Dynamics Limb Sounder (HIRDLS), Measurements of Pollution in the Troposphere (MOPITT), the Tropospheric Emission Spectrometer (TES), and the Stratospheric Aerosol and Gas Experiment (SAGE III). The HITRAN program is also involved in the Ozone Monitoring Experiment (OMI). The data requirements of these programs in terms of spectroscopy are varied with respect to constituents being observed, required remote-sensing parameters, and spectral coverage. A general requisite is for additional spectral parameters and improvements to existing molecular bands sufficient for the simulation of the observations leading to retrieval of the atmospheric state. In addition, cross-section data for heavier molecular species must be expanded and made amenable to modeling in remote sensing. The effort in the project also includes developing software and distribution to make access, manipulation, and use of HITRAN functional to the EOS program.

  8. High-Resolution Spectroscopic Database for the NASA Earth Observing System Program

    NASA Technical Reports Server (NTRS)

    Rothman, Laurence S.

    2004-01-01

    The purpose of this project is to develop and enhance the HITRAN molecular spectroscopic database and associated - software to support the observational programs of the Earth observing System (EOS). In particular, the focus is on the EOS projects: the Atmospheric Infrared Sounder (AIRS), the High-Resolution Dynamics Limb Sounder (HIRDLS), Measurements of Pollution in the Troposphere (MOPITT), the Tropospheric Emission Spectrometer (TES), and the Stratospheric Aerosol and Gas Experiment (SAGE III). The HITRAN program is also involved in the Ozone Monitoring Experiment (OMI). The data requirements of these programs in terms of spectroscopy are varied with respect to constituents being observed, required remote-sensing parameters, and spectral coverage. A general requisite is for additional spectral parameters and improvements to existing molecular bands sufficient for the simulation of the observations leading to retrieval of the atmospheric state. In addition cross-section data for heavier molecular species must be expanded and made amenable to modeling in remote sensing. The effort in the project also includes developing software and distribution to make access, manipulation, and use HITRAN functional to the EOS program.

  9. High Resolution Spectroscopic Database for the NASA Earth Observing System Program

    NASA Technical Reports Server (NTRS)

    Rothman, Laurence

    2004-01-01

    The purpose of this project has been to develop and enhance the HITRAN molecular spectroscopic database and associated software to support the observational programs of the Earth Observing System (EOS). Emphasis has been on the EOS projects: the Atmospheric Infrared Sounder (AIRS), the High-Resolution Dynamics Limb Sounder (HIRDLS), Measurements of Pollution in the Troposphere (MOPITT), the Tropospheric Emission Spectrometer (TES), and the Stratospheric Aerosol and Gas Experiment (SAGE III). The HITRAN program is also involved in the Ozone Monitoring Experiment (OMI). The data requirements of these programs in terms of spectroscopy are varied with respect to constituents being observed, required remote-sensing parameters, and spectral coverage. A general requisite is for additional spectral parameters and improvements to existing molecular bands sufficient for the simulation of the observations leading to retrieval of the atmospheric state. In addition, cross-section data for heavier molecular species must be expanded and made amenable to modeling in remote sensing. The effort in the project also includes developing software and distribution to make access, manipulation, and use of HITRAN functional to the EOS program.

  10. Solar Flares Observed with the Ramaty High Energy Solar Spectroscopic Imager (RHESSI)

    NASA Technical Reports Server (NTRS)

    Holman, Gordon D.

    2004-01-01

    Solar flares are impressive examples of explosive energy release in unconfined, magnetized plasma. It is generally believed that the flare energy is derived from the coronal magnetic field. However, we have not been able to establish the specific energy release mechanism(s) or the relative partitioning of the released energy between heating, particle acceleration (electrons and ions), and mass motions. NASA's RHESSI Mission was designed to study the acceleration and evolution of electrons and ions in flares by observing the X-ray and gamma-ray emissions these energetic particles produce. This is accomplished through the combination of high-resolution spectroscopy and spectroscopic imaging, including the first images of flares in gamma rays. RHESSI has observed over 12,000 solar flares since its launch on February 5, 2002. I will demonstrate how we use the RHESSI spectra to deduce physical properties of accelerated electrons and hot plasma in flares. Using images to estimate volumes, w e typically find that the total energy in accelerated electrons is comparable to that in the thermal plasma. I will also present flare observations that provide strong support for the presence of magnetic reconnection in a large-scale, vertical current sheet in the solar corona. RHESSI observations such as these are allowing us to probe more deeply into the physics of solar flares.

  11. IMAGING AND SPECTROSCOPIC OBSERVATIONS OF MAGNETIC RECONNECTION AND CHROMOSPHERIC EVAPORATION IN A SOLAR FLARE

    SciTech Connect

    Tian, Hui; Reeves, Katharine K.; Raymond, John C.; Chen, Bin; Murphy, Nicholas A.; Li, Gang; Guo, Fan; Liu, Wei

    2014-12-20

    Magnetic reconnection is believed to be the dominant energy release mechanism in solar flares. The standard flare model predicts both downward and upward outflow plasmas with speeds close to the coronal Alfvén speed. Yet, spectroscopic observations of such outflows, especially the downflows, are extremely rare. With observations of the newly launched Interface Region Imaging Spectrograph (IRIS), we report the detection of a greatly redshifted (∼125 km s{sup –1} along the line of sight) Fe XXI 1354.08 Å emission line with a ∼100 km s{sup –1} nonthermal width at the reconnection site of a flare. The redshifted Fe XXI feature coincides spatially with the loop-top X-ray source observed by RHESSI. We interpret this large redshift as the signature of downward-moving reconnection outflow/hot retracting loops. Imaging observations from both IRIS and the Atmospheric Imaging Assembly (AIA) on board the Solar Dynamics Observatory also reveal the eruption and reconnection processes. Fast downward-propagating blobs along these loops are also found from cool emission lines (e.g., Si IV, O IV, C II, Mg II) and images of AIA and IRIS. Furthermore, the entire Fe XXI line is blueshifted by ∼260 km s{sup –1} at the loop footpoints, where the cool lines mentioned above all exhibit obvious redshift, a result that is consistent with the scenario of chromospheric evaporation induced by downward-propagating nonthermal electrons from the reconnection site.

  12. Revised spectroscopic parameters of SH(+) from ALMA and IRAM 30m observations.

    PubMed

    Müller, Holger S P; Goicoechea, Javier R; Cernicharo, José; Agúndez, Marcelino; Pety, Jérôme; Cuadrado, Sara; Gerin, Maryvonne; Dumas, Gaëlle; Chapillon, Edwige

    2014-09-19

    Hydrides represent the first steps of interstellar chemistry. Sulfanylium (SH(+)), in particular, is a key tracer of energetic processes. We used ALMA and the IRAM 30 m telescope to search for the lowest frequency rotational lines of SH(+) toward the Orion Bar, the prototypical photo-dissociation region illuminated by a strong UV radiation field. On the basis of previous Herschel/HIFI observations of SH(+), we expected to detect emission of the two SH(+) hyperfine structure (HFS) components of the NJ = 10-01 fine structure (FS) component near 346 GHz. While we did not observe any lines at the frequencies predicted from laboratory data, we detected two emission lines, each ~15 MHz above the SH(+) predictions and with relative intensities and HFS splitting expected for SH(+). The rest frequencies of the two newly detected lines are more compatible with the remainder of the SH(+) laboratory data than the single line measured in the laboratory near 346 GHz and previously attributed to SH(+). Therefore, we assign these new features to the two SH(+) HFS components of the NJ = 10-01 FS component and re-determine its spectroscopic parameters, which will be useful for future observations of SH(+), in particular if its lowest frequency FS components are studied. Our observations demonstrate the suitability of these lines for SH(+) searches at frequencies easily accessible from the ground. PMID:26525172

  13. Identifying the Young Low-mass Stars within 25 pc. I. Spectroscopic Observations

    NASA Astrophysics Data System (ADS)

    Shkolnik, Evgenya; Liu, Michael C.; Reid, I. Neill

    2009-07-01

    We have completed a high-resolution (R ≈ 60,000) optical spectroscopic survey of 185 nearby M dwarfs identified using ROSAT data to select active, young objects with fractional X-ray luminosities comparable to or greater than Pleiades members. Our targets are drawn from the NStars 20 pc census and the Moving-M sample with distances determined from parallaxes or spectrophotometric relations. We limited our sample to 25 pc from the Sun, prior to correcting for pre-main-sequence overluminosity or binarity. Nearly half of the resulting M dwarfs are not present in the Gliese catalog and have no previously published spectral types. We identified 30 spectroscopic binaries (SBs) from the sample, which have strong X-ray emission due to tidal spin-up rather than youth. This is equivalent to a 16% SB fraction, with at most a handful of undiscovered SBs. We estimate upper limits on the age of the remaining M dwarfs using spectroscopic youth indicators such as surface gravity-sensitive indices (CaH and K I). We find that for a sample of field stars with no metallicity measurements, a single CaH gravity index may not be sufficient, as higher metallicities mimic lower gravity. This is demonstrated in a subsample of metal-rich radial velocity (RV) standards, which appear to have low surface gravity as measured by the CaH index, yet show no other evidence of youth. We also use additional youth diagnostics such as lithium absorption and strong Hα emission to set more stringent age limits. Eleven M dwarfs with no Hα emission or absorption are likely old (>400 Myr) and were caught during an X-ray flare. We estimate that our final sample of the 144 youngest and nearest low-mass objects in the field is less than 300 Myr old, with 30% of them being younger than 150 Myr and four very young (lap10 Myr), representing a generally untapped and well-characterized resource of M dwarfs for intensive planet and disk searches. Based on observations collected at the W. M. Keck Observatory and

  14. Possibility of Detecting the H2O Snowline in Protoplanetary Disks Using Spectroscopic Observations

    NASA Astrophysics Data System (ADS)

    Notsu, Shota; Nomura, Hideko; Ishimoto, Daiki; Walsh, Catherine; Honda, Mitsuhiko; Millar, Thomas J.

    2015-08-01

    Inside the H2O snowline in protoplanetary disks, H2O evaporates from grain surfaces into the gas. On the other hand, it is frozen out on the grain surface in the cold region beyond the H2O snowline. The H2O snowline is thought to divide the regions of rocky planet and gas giant planet formation. Observationally measuring the position of the H2O snowline in protoplanetary disks in exoplanetary systems will constrain modern theories of planet formation. In disks around solar-mass T-tauri stars, the H2O snowline is thought to exist at a few AU from the central star. Therefore, it is difficult to detect the H2O snowline of exoplanetary systems by direct imaging, since the spatial resolution of existing telescopes is insufficient. In this work, we propose a method of detecting the H2O snowline directly by analyzing the velocity profiles of H2O line spectra which can be obtained by high dispersion spectroscopic observations in the near future.First, we use self-consistent physical models of protoplanetary disks (e.g., Nomura & Millar 2005, Nomura et al. 2007, Walsh et al. 2010, 2012) to investigate the abundance distribution of H2O gas and the position of the snowline. We confirm that the abundance of H2O gas is high not only inside the H2O snowline near the equatorial plane but also in the hot surface layer of the outer disk. Second, we calculate the emergent intensity of H2O emission lines from protoplanetary disks that are assumed to rotate with Keplerian velocity profiles. We can find information on the H2O snowline through investigating the profiles of emission lines that have small Einstein A coefficients and large excitation energies. The wavelengths of the useful H2O emission lines range from mid-infrared to sub-millimeter wavelengths. These lines will be observable with future high dispersion spectroscopic observations (e.g., ALMA, TMT).

  15. Generation and evolution of impact-induced vapor clouds: Spectroscopic observations and hydrodynamic calculations

    NASA Astrophysics Data System (ADS)

    Sugita, Seiji

    1999-11-01

    behind the vaporization phenomena during hypervelocity impacts. I developed a new spectroscopic technique to observe thermodynamical quantities of highly transient impact vapor clouds. Finally, I returned to the problem of the interaction between impact-induced vapor clouds and an atmosphere with the newly developed spectroscopic technique. Extensive comparison was made between the experimental results and theoretical calculations in order to find processes overlooked in previous theoretical considerations.

  16. Spectroscopic observations and modelling of impulsive Alfvén waves along a polar coronal jet

    NASA Astrophysics Data System (ADS)

    Jelínek, P.; Srivastava, A. K.; Murawski, K.; Kayshap, P.; Dwivedi, B. N.

    2015-09-01

    Context. The magnetic reconnection in the solar corona results in impulsively generated Alfvén waves, which drive a polar jet. Aims: Using the Hinode/EIS 2'' spectroscopic observations, we study the intensity, velocity, and full width at half maximum (FWHM) variations of the strongest Fe XII 195.12 Å line along the jet to find the signature of Alfvén waves. We numerically simulate the impulsively generated Alfvén waves within the vertical Harris current sheet, forming the jet plasma flows, and mimicking their observational signatures. Methods: Using the FLASH code and an atmospheric model with an embedded, weakly expanding magnetic field configuration within a vertical Harris current sheet, we solve the 2.5-dimensional (2.5D) ideal magnetohydrodynamic (MHD) equations to study the evolution of Alfvén waves and vertical flows forming the plasma jet. Results: At a height of ~5 Mm from the base of the jet, the red-shifted velocity component of Fe XII 195.12 Å line attains its maximum (5 km s-1), which converts into a blue-shifted velocity component between the altitude of 5-10 Mm. The spectral intensity continuously increases up to 10 Mm, while the FWHM still exhibits low values with an almost constant trend. This indicates that the reconnection point within the jet's magnetic field topology lies in the corona 5-10 Mm from its footpoint anchored in the Sun's surface. Beyond this height, the FWHM shows a growing trend. This may be the signature of Alfvén waves that impulsively evolve, due to reconnection, and propagate along the jet. From our numerical data, we evaluate space- and time- averaged Alfvén waves velocity amplitudes at different heights in the jet's current sheet, which contribute to the non-thermal motions and spectral line broadening. The synthetic width of Fe XII 195.12 Å line exhibits a similar trend of increment as in the observational data, possibly proving the existence of Alfvén waves, impulsively generated by reconnection, that propagate

  17. Visible Spectroscopic Observation Of Asteroid 162173 (1999ju3) With The Gemini-s Telescope

    NASA Astrophysics Data System (ADS)

    Sugita, Seiji; Kuroda, D.; Kameda, S.; Hasegawa, S.; Kamata, S.; Abe, M.; Ishiguro, M.; Takato, N.; Yoshikawa, M.

    2012-10-01

    Asteroid 162173 (1999JU3; hereafter JU3) is the target of the Hayabusa-2 mission. Its visible reflectance spectra have been observed a few times [1,2], and obtained spectra exhibit a wide variety of spectral patterns ranging from a spectra with absorption in the UV region (May 1999) to a flat spectrum with a faint broad absorption centered around 0.6 microns (September 2007) and that with UV absorption and strong broad absorption centered around 0.7 micron (July 2007). The apparent large spectral variation may be due to variegation on the asteroid surface. Such variegation would make a large influence on remote sensing strategy for Hayabusa-2 before its sampling operations. In order to better constraint the spectral properties of JU3, we conducted visible spectroscopic observations at the GEMINI-South observatory 8.1-m telescope with the GMOS instrument. We could obtain three different sets of data in June and July 2012. Although the JU3 rotation phases of two of the observation are close to each other, the other is about 120 degrees away from the two. Our preliminary analyses indicate that these three spectra are slightly reddish but generally flat across the observed wavelength range (0.47 - 0.89 microns). The observed flat spectra are most similar to the spectrum obtained in September 2007, which probably has the highest signal-to-noise ratio among the previous three spectra. This result suggests that material with a flat spectrum probably covers a dominant proportion of the JU3 surface and that the other two types of previously obtained spectra may not cover a very large fraction of the JU3 surface. [1] Binzel, R. P. et al. (2001) Icarus, 151, 139-149; [2] Vilas, F. (2008) AJ, 135, 1101-1105.

  18. Revised spectroscopic parameters of SH+ from ALMA and IRAM 30 m observations

    NASA Astrophysics Data System (ADS)

    Müller, Holger S. P.; Goicoechea, Javier R.; Cernicharo, José; Agúndez, Marcelino; Pety, Jérôme; Cuadrado, Sara; Gerin, Maryvonne; Dumas, Gaëlle; Chapillon, Edwige

    2014-09-01

    Hydrides represent the first steps of interstellar chemistry. Sulfanylium (SH+), in particular, is a key tracer of energetic processes. We used ALMA and the IRAM 30 m telescope to search for the lowest frequency rotational lines of SH+ toward the Orion Bar, the prototypical photo-dissociation region illuminated by a strong UV radiation field. On the basis of previous Herschel/HIFI observations of SH+, we expected to detect emission of the two SH+ hyperfine structure (HFS) components of the NJ = 10-01 fine structure (FS) component near 346 GHz. While we did not observe any lines at the frequencies predicted from laboratory data, we detected two emission lines, each ~15 MHz above the SH+ predictions and with relative intensities and HFS splitting expected for SH+. The rest frequencies of the two newly detected lines are more compatible with the remainder of the SH+ laboratory data than the single line measured in the laboratory near 346 GHz and previously attributed to SH+. Therefore, we assign these new features to the two SH+ HFS components of the NJ = 10-01 FS component and re-determine its spectroscopic parameters, which will be useful for future observations of SH+, in particular if its lowest frequency FS components are studied. Our observations demonstrate the suitability of these lines for SH+ searches at frequencies easily accessible from the ground. This paper makes use of the following ALMA data: ADS/JAO.ALMA#2012.1.00352.S. ALMA is a partnership of ESO (representing its member states), NSF (USA) and NINS (Japan), together with NRC (Canada) and NSC and ASIAA (Taiwan), in cooperation with the Republic of Chile. The Joint ALMA Observatory is operated by ESO, AUI/NRAO and NAOJ.This paper makes use of observations obtained with the IRAM 30 m telescope. IRAM is supported by INSU/CNRS (France), MPG (Germany), and IGN (Spain).Appendix A is available in electronic form at http://www.aanda.org

  19. A SURVEY OF FAR ULTRAVIOLET SPECTROSCOPIC EXPLORER OBSERVATIONS OF CATACLYSMIC VARIABLES

    SciTech Connect

    Froning, Cynthia S.; Long, Knox S.; Gaensicke, Boris; Szkody, Paula E-mail: long@stsci.edu E-mail: szkody@alicar.astro.washington.edu

    2012-03-01

    During its lifetime, the Far Ultraviolet Spectroscopic Explorer (FUSE) was used to observe 99 cataclysmic variables (CVs) in 211 separate observations. Here, we present a survey of the moderate-resolution (R {approx_equal} 10, 000), far-ultraviolet (905-1188 A), time-averaged FUSE spectra of CVs. The FUSE spectra are morphologically diverse. They show contributions from the accretion disk, the disk chromosphere, disk outflows, and the white dwarf (WD), but the relative contribution of each component varies widely as a function of CV subtype, orbital period and evolutionary state, inclination, mass accretion rate, and magnetic field strength of the WD. The data reveal information about the structure, temperature, density and mass flow rates of the disk and disk winds, the temperature of the WD and the effects of ongoing accretion on its structure, and the long-term response of the systems to disk outbursts. The complete atlas of time-averaged FUSE spectra of CVs is available at the Multimission Archive at Space Telescope Science Institute as a High Level Science Product.

  20. Direct spectroscopic observation of a shallow hydrogenlike donor state in insulating SrTiO3.

    PubMed

    Salman, Z; Prokscha, T; Amato, A; Morenzoni, E; Scheuermann, R; Sedlak, K; Suter, A

    2014-10-10

    We present a direct spectroscopic observation of a shallow hydrogenlike muonium state in SrTiO(3) which confirms the theoretical prediction that interstitial hydrogen may act as a shallow donor in this material. The formation of this muonium state is temperature dependent and appears below ∼ 70K. From the temperature dependence we estimate an activation energy of ∼ 50 meV in the bulk and ∼ 23 meV near the free surface. The field and directional dependence of the muonium precession frequencies further supports the shallow impurity state with a rare example of a fully anisotropic hyperfine tensor. From these measurements we determine the strength of the hyperfine interaction and propose that the muon occupies an interstitial site near the face of the oxygen octahedron in SrTiO(3). The observed shallow donor state provides new insight for tailoring the electronic and optical properties of SrTiO(3)-based oxide interface systems. PMID:25375730

  1. Additional spectroscopic observations and Swift monitoring of the M31 nova iPTF16bqy (ASASSN-16hf)

    NASA Astrophysics Data System (ADS)

    Chinetti, K.; Darnley, M. J.; Page, K. L.; Williams, S. C.

    2016-08-01

    We report additional spectroscopic observations of the M31 nova, iPTF16bqy (ASASSN-16hf, ATels #9245, #9248). iPTF16bqy was initially classified as a Fe II nova based on spectra obtained 2016 July 14 and 15 (ATel #9248), about two days after discovery.

  2. Psychological factors, beliefs about medication, and adherence of youth with human immunodeficiency virus in a multisite directly observed therapy pilot study.

    PubMed

    Garvie, Patricia A; Flynn, Patricia M; Belzer, Marvin; Britto, Paula; Hu, Chengcheng; Graham, Bobbie; Neely, Michael; McSherry, George D; Spector, Stephen A; Gaur, Aditya H

    2011-06-01

    This study examined psychological functioning and beliefs about medicine in adolescents with human immunodeficiency virus (HIV) on highly active antiretroviral therapy in a community-based directly observed therapy (DOT) pilot feasibility study. Participants were youth with behaviorally acquired HIV (n = 20; 65% female; median age, 21 years) with adherence problems, who received once-daily DOT. Youth were assessed at baseline, week 12 (post-DOT), and week 24 (follow-up). At baseline, 55% of youth reported having clinical depressive symptoms compared to 27% at week 12 with sustained improvements at week 24. At baseline, substance use was reported within the borderline clinical range (T(score) = 68), with clinical but statistically nonsignificant improvement (T(score) = 61) at week 12. Hopelessness scores reflected optimism for the future. Coping strategies showed significantly decreased cognitive avoidance (p = .02), emotional discharge (p = .004), and acceptance/resignation ("nothing I can do," p = .004), whereas positive reappraisal and seeking support emerged. With the exception of depressive symptoms, week 12 improvements were not sustained at week 24. DOT adherence was predicted by higher baseline depression (p = .05), beliefs about medicine (p = .006) and perceived threat of illness scores (p = .03). Youth with behaviorally acquired HIV and adherence problems who participated in a community-based DOT intervention reported clinically improved depressive symptoms, and temporarily reduced substance use and negative coping strategies. Depressive symptoms, beliefs about medicine, and viewing HIV as a potential threat predicted better DOT adherence. PMID:21575827

  3. NIR SPECTROSCOPIC OBSERVATION OF MASSIVE GALAXIES IN THE PROTOCLUSTER AT z = 3.09

    SciTech Connect

    Kubo, Mariko; Yamada, Toru; Ichikawa, Takashi; Kajisawa, Masaru; Matsuda, Yuichi; Tanaka, Ichi

    2015-01-20

    We present the results of near-infrared spectroscopic observations of the K-band-selected candidate galaxies in the protocluster at z = 3.09 in the SSA22 field. We observed 67 candidates with K {sub AB} < 24 and confirmed redshifts of the 39 galaxies at 2.0 < z {sub spec} < 3.4. Of the 67 candidates, 24 are certainly protocluster members with 3.04 ≤ z {sub spec} ≤ 3.12, which are massive red galaxies that have been unidentified in previous optical observations of the SSA22 protocluster. Many distant red galaxies (J – K {sub AB} > 1.4), hyper extremely red objects (J – K {sub AB} > 2.1), Spitzer MIPS 24 μm sources, active galactic nuclei (AGNs) as well as the counterparts of Lyα blobs and the AzTEC/ASTE 1.1 mm sources in the SSA22 field are also found to be protocluster members. The mass of the SSA22 protocluster is estimated to be ∼2-5 × 10{sup 14} M {sub ☉}, and this system is plausibly a progenitor of the most massive clusters of galaxies in the current universe. The reddest (J – K {sub AB} ≥ 2.4) protocluster galaxies are massive galaxies with M {sub star} ∼ 10{sup 11} M {sub ☉} showing quiescent star formation activities and plausibly dominated by old stellar populations. Most of these massive quiescent galaxies host moderately luminous AGNs detected by X-ray. There are no significant differences in the [O III] λ5007/Hβ emission line ratios and [O III] λ5007 line widths and spatial extents of the protocluster galaxies from those of massive galaxies at z ∼ 2-3 in the general field.

  4. A spectroscopic survey for lambda Bootis stars. II. The observational data

    NASA Astrophysics Data System (ADS)

    Paunzen, E.; Duffee, B.; Heiter, U.; Kuschnig, R.; Weiss, W. W.

    2001-07-01

    lambda Bootis stars comprise only a small number of all A-type stars and are characterized as nonmagnetic, Population i, late B to early F-type dwarfs which show significant underabundances of metals whereas the light elements (C, N, O and S) are almost normal abundant compared to the Sun. In the second paper on a spectroscopic survey for lambda Bootis stars, we present the spectral classifications of all program stars observed. These stars were selected on the basis of their Strömgren uvbybeta colors as lambda Bootis candidates. In total, 708 objects in six open clusters, the Orion OB1 association and the Galactic field were classified. In addition, 9 serendipity non-candidates in the vicinity of our program stars as well as 15 Guide Star Catalogue stars were observed resulting in a total of 732 classified stars. The 15 objects from the Guide Star Catalogue are part of a program for the classification of apparent variable stars from the Fine Guidance Sensors of the Hubble Space Telescope. A grid of 105 MK standard as well as ``pathological'' stars guarantees a precise classification. A comparison of our spectral classification with the extensive work of Abt & Morrell (\\cite{Abt95}) shows no significant differences. The derived types are 0.23 +/- 0.09 (rms error per measurement) subclasses later and 0.30 +/- 0.08 luminosity classes more luminous than those of Abt & Morrell (\\cite{Abt95}) based on a sample of 160 objects in common. The estimated errors of the means are +/- 0.1 subclasses. The characteristics of our sample are discussed in respect to the distribution on the sky, apparent visual magnitudes and Strömgren uvbybeta colors. Based on observations from the Observatoire de Haute-Provence, Osservatorio Astronomico di Padova-Asiago, Observatório do Pico dos Dias-LNA/CNPq/MCT, Chews Ridge Observatory (MIRA) and University of Toronto Southern Observatory (Las Campanas).

  5. NIR Spectroscopic Observation of Massive Galaxies in the Protocluster at z = 3.09

    NASA Astrophysics Data System (ADS)

    Kubo, Mariko; Yamada, Toru; Ichikawa, Takashi; Kajisawa, Masaru; Matsuda, Yuichi; Tanaka, Ichi

    2015-01-01

    We present the results of near-infrared spectroscopic observations of the K-band-selected candidate galaxies in the protocluster at z = 3.09 in the SSA22 field. We observed 67 candidates with K AB < 24 and confirmed redshifts of the 39 galaxies at 2.0 < z spec < 3.4. Of the 67 candidates, 24 are certainly protocluster members with 3.04 <= z spec <= 3.12, which are massive red galaxies that have been unidentified in previous optical observations of the SSA22 protocluster. Many distant red galaxies (J - K AB > 1.4), hyper extremely red objects (J - K AB > 2.1), Spitzer MIPS 24 μm sources, active galactic nuclei (AGNs) as well as the counterparts of Lyα blobs and the AzTEC/ASTE 1.1 mm sources in the SSA22 field are also found to be protocluster members. The mass of the SSA22 protocluster is estimated to be ~2-5 × 1014 M ⊙, and this system is plausibly a progenitor of the most massive clusters of galaxies in the current universe. The reddest (J - K AB >= 2.4) protocluster galaxies are massive galaxies with M star ~ 1011 M ⊙ showing quiescent star formation activities and plausibly dominated by old stellar populations. Most of these massive quiescent galaxies host moderately luminous AGNs detected by X-ray. There are no significant differences in the [O III] λ5007/Hβ emission line ratios and [O III] λ5007 line widths and spatial extents of the protocluster galaxies from those of massive galaxies at z ~ 2-3 in the general field.

  6. Near-Simultaneous Spectroscopic and Broadband Polarimetric Observations of Be Stars

    NASA Technical Reports Server (NTRS)

    Ghosh, K.; Iyengar, K. V. K.; Ramsey, B. D.; Austin, R. A.

    1999-01-01

    Near simultaneous optical spectroscopic (on four nights) and broadband linear continuum (B, V, R, and I bands) polarimetric (on seven nights) observations of 29 Be stars were carried out during 1993 November-December. The program Be stars displayed wavelength dependence of intrinsic polarizations with no frequency dependence of polarimetric position angles. Some of the Be stars displayed long-term polarization variability. The Be and Be-shell stars could not be distinguished from one another solely on the basis of their polarization values. Full widths at half-maximum of the H.alpha profiles and the intrinsic linear continuum polarizations are closely correlated with the projected rotational velocities of the program stars. Photospheric-absorption-corrected equivalent widths of H.alpha profiles [W(alpha)] and the radii of H.alpha-emitting or -absorbing envelopes (R(sub e) or R(sub a)) are nonlinearly correlated with the intrinsic continuum polarizations of these stars. However, W(alpha) and R(sub e) are linearly correlated. With large uncertainties, there is a trend of spectral dependence of polarization. Detailed discussion of these results is presented in this paper.

  7. New spectroscopic and photometric observations of CV J0644+3344

    NASA Astrophysics Data System (ADS)

    Hernández Santisteban, J. V.

    We report photometric and simultaneous spectroscopic observations of the cataclysmic variable J0644+3344 and present calibrated Doppler tomography results of the object. We have calibrated the spectra for slit losses using simultaneous photometry. This has been used to construct reliable Doppler images in the Halpha , Hbeta and He II 4686 Å@ emission lines. We have also performed a radial velocity analysis using these emission lines to derive the primary semi-amplitude and used a cophasing method to determine the secondary K_2 best value. We have improved the ephemeris of the object based on the published and our new photometric eclipse timings to obtain HJD=254474.7927+0.26937446E. We derived a K_1=123.2±6.6 {km s}-1 and K_2=205.4±6.7. Assuming a i>76, the orbital parameters are M_1=0.91±0.04 M⊙, M_2=0.83±0.04 M⊙ and a=2.10±0.03 R⊙. Based on the Doppler tomography we conclude that J0644+3344 is a nova-like SW Sex type system.

  8. Spectroscopic Observations and Analysis of the Unusual Type Ia SN1999ac

    SciTech Connect

    Garavini, G.; Aldering, G.; Amadon, A.; Amanullah, R.; Astier,P.; Balland, C.; Blanc, G.; Conley, A.; Dahlen, T.; Deustua, S.E.; Ellis,R.; Fabbro, S.; Fadeyev, V.; Fan, X.; Folatelli, G.; Frye, B.; Gates,E.L.; Gibbons, R.; Goldhaber, G.; Goldman, B.; Goobar, A.; Groom, D.E.; Haissinski, J.; Hardin, D.; Hook, I.; Howell, D.A.; Kent, S.; Kim, A.G.; Knop, R.A.; Kowalski, M.; Kuznetsova, N.; Lee, B.C.; Lidman, C.; Mendez,J.; Miller, G.J.; Moniez, M.; Mouchet, M.; Mourao, A.; Newberg, H.; Nobili, S.; Nugent, P.E.; Pain, R.; Perdereau, O.; Perlmutter, S.; Quimby, R.; Regnault, N.; Rich, J.; Richards, G.T.; Ruiz-Lapuente, P.; Schaefer, B.E.; Schahmaneche, K.; Smith, E.; Spadafora, A.L.; Stanishev,V.; Thomas, R.C.; Walton, N.A.; Wang, L.; Wood-Vasey, W.M.

    2005-07-12

    The authors present optical spectra of the peculiar Type Ia supernova (SN Ia) 1999ac. The data extend from -15 to +42 days with respect to B-band maximum and reveal an event that is unusual in several respects. prior to B-band maximum, the spectra resemble those of SN 1999aa, a slowly declining event, but possess stronger Si II and Ca II signatures (more characteristic of a spectroscopically normal SN). Spectra after B-band maximum appear more normal. The expansion velocities inferred from the Iron lines appear to be lower than average; whereas, the expansion velocity inferred from Calcium H and K are higher than average. The expansion velocities inferred from the Iron lines appear to be lower than average; whereas, the expansion velocity inferred from Calcium H and K are higher than average. The expansion velocities inferred from Si II are among the slowest ever observed, though SN 1999ac is not particularly dim. The analysis of the parameters v{sub 10}(Si II), R(Si II), v, and {Delta}m{sub 15} further underlines the unique characteristics of SN 1999ac. They find convincing evidence of C II {lambda}6580 in the day -15 spectrum with ejection velocity v > 16,000 km s{sup -1}, but this signature disappears by day -9. This rapid evolution at early times highlights the importance of extremely early-time spectroscopy.

  9. Vertical profiling of methane and carbon dioxide using high resolution near-infrared heterodyne spectroscopic observations

    NASA Astrophysics Data System (ADS)

    Rodin, Alexander; Klimchuk, Artem; Churbanov, Dmitry; Pereslavtseva, Anastasia; Spiridonov, Maxim; Nadezhdinskyi, Alexander

    2014-05-01

    We present new method of monitoring greenhouse gases using spectroscopic observations of solar radiation passed through the atmosphere with spectral resolution ΛvδΛ up to 108. Such a high resolution is achieved by heterodyne technique and allows to retrieve full information about spectral line shape which, in turn, is used to distinguish contribution of different atmospheric layers to the resulting absorption. Weak absorption line at 6056.5 cm-1 was selected for CO2 measurements and a quartet of lines centered at 6057 cm-1for CH4. The instrument setup includes Sun tracker with a microtelescope and chopper, diode DFB laser used as a local oscillator, a bundle of single mode optical fibers that provides medium for radiation transfer and beam coupling, reference cell with depressurized methane for LO frequency stabilization, and Fabry-Perot etalon for LO frequency calibration. A commercial p-i-n diode with squared detector replaces a mixer and IF spectrometer, providing measurement of heterodyne beating within a bandpass of few MHz, which determines the effective spectral resolution of the instrument. Spectral coverage within narrow range (about 1 cm-1) is provided by ramping the LO frequency based on feedback from the reference channel. Observations of Sun in the Moscow region have resulted for the first time in measurements of the atmospheric transmission near 1.65 μm with sub-Doppler spectral resolution. In order to retrieve vertical profiles of methane and carbon dioxide we developed the inversion algorithm implementing Tikhonov regularization approach. With measured transmission having S/N ratio of 100 or higher, the uncertainty of CH4 profile is about 10 ppb, with the uncertainty of CO2 profile at 1 ppm. This techniques is promising an affordable opportunity or widespread monitoring of greenhouse gases and may be implemented on existing ground-based stations. This work has been supported by the grant of Russian Ministry of education and science #11.G34.31.0074

  10. Near-infrared spectroscopic observations of Comets by Japanese Infrared Satellite

    NASA Astrophysics Data System (ADS)

    Kobayashi, Hitomi; Yamaguchi, Mitsuru; Ootsubo, Takafumi; Kawakita, Hideyo; Hamada, Saki

    Comets are thought to be one of the primeordial bodies in the solar system. Chemical abun-dances of the cometary icy materials are precious clue to the conditions in the early solar system. H2O is the most abundant species of the cometry nucleus, but CO and CO2 are also abundant with diversities. Especially, CO2 cannot be directly observed by ground-based ob-servations because of the strong absorption by telluric CO2. Thus, only the space observatory (or spacecraft) can access CO2 in comets directly. We observed some comets by "AKARI", Japanese infrared satellite. It has 68.5 cm telescope with InfraRed Camera (IRC). The IRC also has a spectroscopic capability (both grism and prism were available for disperser). The data we present were taken by the IRC in the grism mode. The IRC with grism can cover the wavelength range from 2.5 to 5 microns where vibrational fundamental bands of H2O, CO2, and CO (at 2.7, 4.3, and 4.7 microns) are usually recognized as emission in cometary spectra. We determined the mixng ratios of CO and CO2 relative to H2O for 5 comets: C/2006 W3, C/2006 OF2, C/2006 W3, /2007 N3, and C/2007 W1. These comets were observed at various heliocetric distances, so their mixing ratios can not be compared directly among these comets. We tried to convert the obtained mixing ratios at various heliocentric distancees to the mixing ratios at 1 AU from the Sun. Previous studies of mixing ratios of CO2 and CO relative to H2O were carried out by the Vega space craft (1P/Halley), ISO (C/1995 O1 and 103P/Hartley 2) and Deep Impcat spacecraft (9P/Tempel 1). We also applied the conversion factors to those prvious works. We will discuss about the diversity of mixing ratios of CO2 and CO in these comets.

  11. GEMINI near-infrared spectroscopic observations of young massive stars embedded in molecular clouds

    NASA Astrophysics Data System (ADS)

    Roman-Lopes, A.; Abraham, Z.; Ortiz, R.; Rodriguez-Ardila, A.

    2009-03-01

    K-band spectra of young stellar candidates in four Southern hemisphere clusters have been obtained with the Gemini Near-Infrared Spectrograph in Gemini South. The clusters are associated with IRAS sources that have colours characteristic of ultracompact HII regions. Spectral types were obtained by comparison of the observed spectra with those of a near-infrared (NIR) library; the results include the spectral classification of nine massive stars and seven objects confirmed as background late-type stars. Two of the studied sources have K-band spectra compatible with those characteristic of very hot stars, as inferred from the presence of CIV, NIII and NV emission lines at 2.078, 2.116 and 2.100 μm, respectively. One of them, I16177_IRS1, has a K-band spectrum similar to that of Cyg OB2 7, an O3If* supergiant star. The nebular K-band spectrum of the associated Ultra-Compact (UC) HII region shows the s-process [KrIII] and [SeIV] high excitation emission lines, previously identified only in planetary nebula. One young stellar object was found in each cluster, associated with either the main IRAS source or a nearby resolved Midecourse Space eXperiment (MSX) component, confirming the results obtained from previous NIR photometric surveys. The distances to the stars were derived from their spectral types and previously determined JHK magnitudes; they agree well with the values obtained from the kinematic method, except in the case of IRAS 15408-5356, for which the spectroscopic distance is about a factor of 2 smaller than the kinematic value.

  12. Far Ultraviolet Spectroscopic Explorer Observation of the Nonradiative Collisionless Shock in the Remnant of SN 1006

    NASA Astrophysics Data System (ADS)

    Korreck, K. E.; Raymond, J. C.; Zurbuchen, T. H.; Ghavamian, P.

    2004-11-01

    The appearance of the young supernova remnant SN 1006 is dominated by emission from nonradiative shocks in the northeast and northwest regions. At X-ray energies the northeast shock exhibits predominantly nonthermal synchrotron emission, while the northwest shock exhibits a thermal spectrum. We present far-ultraviolet spectra of the northeast (NE) and northwest (NW) portions of SN 1006 acquired with the Far Ultraviolet Spectroscopic Explorer (FUSE). We have detected emission lines of O VI λλ1032, 1038 and broad Lyβ λ1025 in the NW filament but detect no emission lines in the NE region down to a level of 4.7×10-17 ergs cm-2 s-1 arcsec-2. We observed in the NW an O VI intensity of 2.0+/-0.2×10-16 ergs cm-2 s-1 arcsec-2 and measured an O VI line width of 2100+/-200 km s-1 at a position where the Hα width was measured to be 2290+/-80 km s-1. This implies less than mass-proportional heating of the ions. Using the ratio of intensities I(NW)/I(NE)~n(NW)/n(NE), the density ratio of the two regions is found to be >=4, a value that is consistent with the uncertainties of the ratio of 2.5 measured in 2003 by Long and coworkers. The derived O VI kinetic temperature is compared to previous estimates of electron, proton, and ion temperatures in the remnant to study the relative heating efficiency of various species at the shock front. The degree of postshock temperature equilibration may be crucial to particle acceleration, since the temperature of each species determines the number of high-speed particles available for injection into an acceleration process that could produce Galactic cosmic rays.

  13. Unveiling the nature of two unidentified EGRET blazar candidates through spectroscopic observations

    NASA Astrophysics Data System (ADS)

    Nkundabakura, P.; Meintjes, P. J.

    2012-11-01

    Studies using the Energetic Gamma-Ray Experiment Telescope (EGRET) revealed that blazars [flat-spectrum radio quasars (FSRQs) and BL Lac objects] emit most of their luminosity in the high-energy gamma-ray (E > 100 MeV) range. From the 271 sources observed by EGRET, 131 are still unidentified. A systematic search is conducted to identify possible high-energy gamma-ray blazars among the unidentified EGRET population. Based upon multiwavelength emission properties, 13 extragalactic radio sources were selected in the EGRET error boxes for further investigation. From the above-mentioned sample, results of a multiwavelength follow-up of two EGRET sources, 3EG J0821-5814 and 3EG J0706-3837, are presented. These sources are associated with their radio counterparts PKS J0820-5705 and PMN J0710-3850, respectively. Spectroscopic observations utilizing the SOAR/Goodman spectrograph at the Cerro Tololo Inter-American Observatory in Chile reveal a spectrum of PKS J0820-5705 that corresponds to that of a radio-loud active galactic nucleus (FSRQ) with redshift z = 0.06 ± 0.01, while the visibility of wide and narrow emission lines in the spectrum of PMN J0710-3850 resembles that of a low-ionization nuclear emission-line region (LINER) or type 1 Seyfert galaxy at z = 0.129 ± 0.001. The observed Ca II K&H lines depression ratio at 4000 Å showed a shallow depression of 8.8 ± 2.5 per cent for PKS J0820-5705 and 80 ± 1 per cent for PMN J0710-3850, suggesting the presence of a strong non-thermal optical contribution in PKS J0820-5705, which clearly distinguishes its spectrum from that of a radio galaxy. The weaker optical non-thermal contribution for PMN J0710-3850 is in accordance with that expected of a LINER. For PMN J0710-3850 the line flux ratios [O III] λ5007/Hβ < 3 and [N II] λ6583/Hα > 0.6 which are in agreement with the expected ratios of LINERs. However, the absence of [O II] λ3727 implies an anomalously low [O II]/[O III] < 0.5 ratio for a LINER, and agrees more

  14. The B0.5 IVe CoRoT target HD 49330. II. Spectroscopic ground-based observations

    NASA Astrophysics Data System (ADS)

    Floquet, M.; Hubert, A.-M.; Huat, A.-L.; Frémat, Y.; Janot-Pacheco, E.; Gutiérrez-Soto, J.; Neiner, C.; de Batz, B.; Leroy, B.; Poretti, E.; Amado, P.; Catala, C.; Rainer, M.; Diaz, D.; Uytterhoeven, K.; Andrade, L.; Diago, P. D.; Emilio, M.; Espinosa Lara, F.; Fabregat, J.; Martayan, C.; Semaan, T.; Suso, J.

    2009-10-01

    Context: We present spectroscopic ground-based observations of the early Be star HD 49330 obtained simultaneously with the CoRoT-LRA1 run just before the burst observed in the CoRoT data. Aims: Ground-based spectroscopic observations of the early Be star HD 49330 obtained during the precursor phase and just before the start of an outburst allow us to disantangle stellar and circumstellar contributions and identify modes of stellar pulsations in this rapidly rotating star. Methods: Time series analysis (TSA) is performed on photospheric line profiles of He I and Si III by means of the least squares method. Results: We find two main frequencies f1 = 11.86 c d-1 and f2 = 16.89 c d-1 which can be associated with high order p-mode pulsations. We also detect a frequency f3 = 1.51 c d-1 which can be associated with a low order g-mode. Moreover we show that the stellar line profile variability changed over the spectroscopic run. These results are in agreement with the results of the CoRoT data analysis, as shown in Huat et al. (2009). Conclusions: Our study of mid- and short-term spectroscopic variability allows the identification of p- and g-modes in HD 49330. It also allows us to display changes in the line profile variability before the start of an outburst. This brings new constraints for the seimic modelling of this star. Based on observations made with ESO Telescopes at La Silla Observatory under the ESO Large Programme: LP178.D-0361, and on data collected with the TBL at Pic du Midi Observatory (France).

  15. VizieR Online Data Catalog: Spectroscopic observations of globular clusters (Sharina+, 2010)

    NASA Astrophysics Data System (ADS)

    Sharina, M. E.; Chandar, R.; Puzia, T. H.; Goudfrooij, P.; Davoust, E.

    2012-03-01

    The spectroscopic data were obtained with the SCORPIO spectrograph installed at the prime focus of the SAO 6-m telescope of the Russian Academy of Sciences in two modes: with long-slit (LS) and multislit (MS) units. (5 data files).

  16. Photometric and spectroscopic observations, and abundance tomography modelling of the Type Ia supernova SN 2014J located in M82

    NASA Astrophysics Data System (ADS)

    Ashall, C.; Mazzali, P.; Bersier, D.; Hachinger, S.; Phillips, M.; Percival, S.; James, P.; Maguire, K.

    2014-12-01

    Spectroscopic and photometric observations of the nearby Type Ia Supernova (SN Ia) SN 2014J are presented. Spectroscopic observations were taken -8 to +10 d relative to B-band maximum, using FRODOSpec, a multipurpose integral-field unit spectrograph. The observations range from 3900 to 9000 Å. SN 2014J is located in M82 which makes it the closest SN Ia studied in at least the last 28 yr. It is a spectroscopically normal SN Ia with high-velocity features. We model the spectra of SN 2014J with a Monte Carlo radiative transfer code, using the abundance tomography technique. SN 2014J is highly reddened, with a host galaxy extinction of E(B - V) = 1.2 (RV = 1.38). It has a Δm15(B) of 1.08 ± 0.03 when corrected for extinction. As SN 2014J is a normal SN Ia, the density structure of the classical W7 model was selected. The model and photometric luminosities are both consistent with B-band maximum occurring on JD 245 6690.4 ± 0.12. The abundance of the SN 2014J behaves like other normal SN Ia, with significant amounts of silicon (12 per cent by mass) and sulphur (9 per cent by mass) at high velocities (12 300 km s-1) and the low-velocity ejecta (v < 6500 km s-1) consists almost entirely of 56Ni.

  17. Far Ultraviolet Spectroscopic Explorer (FUSE) observations of emitting and absorbing gas in the Local Interstellar Chimney

    NASA Astrophysics Data System (ADS)

    Welsh, B. Y.; Sallmen, S.; Sfeir, D.; Shelton, R. L.; Lallement, R.

    2002-11-01

    We present Far Ultraviolet Spectroscopic Explorer (FUSE) satellite measurements of the absorption and emission characteristics of interstellar gas associated with the Local Interstellar Chimney, which is an extension of the rarefied Local Bubble cavity that extends outward from the galactic disk towards the lower galactic halo. Far ultraviolet (FUV) diffuse background emission has been detected in the high ionization line of O VI (lambda 1032 Å) for two lines-of-sight (l = 162.7deg, b = +57.0deg) and (l = 156.3deg, b = +57.8deg) at emission levels of 2500+/-700 photons cm-2 s-1 sr-1 (LU) and 3300+/-1100 LU respectively. These levels of O VI emission are very similar to those found for four other lines-of-sight sampled thus far by the FUSE satellite, implying a fairly constant level of average O VI surface brightness emission at high galactic latitudes of about 2700 LU with a standard deviation of 450 LU. These emission-line data are supplemented by FUV interstellar absorption line measurements taken towards the hot DA white dwarf star, REJ 1032+532 (l = 157.5deg, b = +53.2deg), whose distance of 116 pc places it within the Local Bubble region. No high ionization interstellar O VI lambda 1032 Å absorption has been detected (N(O VI) < 13.0 cm-2), which is consistent with the non-detections of interstellar C IV and Si IV absorption reported towards this star by Holberg et al. (\\cite{holberg99a}). Taken together, our FUV absorption and emission data may be explained by a scenario in which the O VI emission and absorption lines are both formed at the conductive interface of the neutral boundary to the Local Bubble. For the presently sampled sight-lines we have found no correlation between the OVI emission line intensity and the associated 0.25 keV soft X-ray background flux as measured in the R1 and R2 bands by the ROSAT satellite. The OVI line intensities also show no correlation with the soft X-ray background flux attributable to emission from the million degree K

  18. How Can Multi-Site Evaluations Be Participatory?

    ERIC Educational Resources Information Center

    Lawrenz, Frances; Huffman, Douglas

    2003-01-01

    Multi-site evaluations are becoming increasingly common in federal funding portfolios. Although much thought has been given to multi-site evaluation, there has been little emphasis on how it might interact with participatory evaluation. Therefore, this paper reviews several National Science Foundation educational, multi-site evaluations for the…

  19. Optical Spectroscopic Observations of Gamma-ray Blazar Candidates. IV. Results of the 2014 Follow-up Campaign

    NASA Astrophysics Data System (ADS)

    Ricci, F.; Massaro, F.; Landoni, M.; D'Abrusco, R.; Milisavljevic, D.; Stern, D.; Masetti, N.; Paggi, A.; Smith, Howard A.; Tosti, G.

    2015-05-01

    The extragalactic γ-ray sky is dominated by the emission arising from blazars, one of the most peculiar classes of radio-loud active galaxies. Since the launch of Fermi several methods were developed to search for blazars as potential counterparts of unidentified γ-ray sources (UGSs). To confirm the nature of the selected candidates, optical spectroscopic observations are necessary. In 2013 we started a spectroscopic campaign to investigate γ-ray blazar candidates selected according to different procedures. The main goals of our campaign are: (1) to confirm the nature of these candidates, and (2) whenever possible, determine their redshifts. Optical spectroscopic observations will also permit us to verify the robustness of the proposed associations and check for the presence of possible source class contaminants to our counterpart selection. This paper reports the results of observations carried out in 2014 in the northern hemisphere with Kitt Peak National Observatory and in the southern hemisphere with the Southern Astrophysical Research telescopes. We also report three sources observed with the Magellan and Palomar telescopes. Our selection of blazar-like sources that could be potential counterparts of UGSs is based on their peculiar infrared colors and on their combination with radio observations both at high and low frequencies (i.e., above and below ˜1 GHz) in publicly available large radio surveys. We present the optical spectra of 27 objects. We confirm the blazar-like nature of nine sources that appear to be potential low-energy counterparts of UGSs. Then we present new spectroscopic observations of 10 active galaxies of uncertain type associated with Fermi sources, classifying all of them as blazars. In addition, we present the spectra for five known γ-ray blazars with uncertain redshift estimates and three BL Lac candidates that were observed during our campaign. We also report the case for WISE J173052.85-035247.2, candidate counterpart of the

  20. Ab initio study of the O4H(+) novel species: spectroscopic fingerprints to aid its observation.

    PubMed

    Xavier, F George D; Hernández-Lamoneda, Rámon

    2015-06-28

    A detailed ab initio characterization of the structural, energetic and spectroscopic properties of the novel O4H(+) species is presented. The equilibrium structures and relative energies of all multiplet states have been determined systematically by analyzing static and dynamical correlation effects. The two and three body dissociation processes have been studied and indicate the presence of conical intersections in various states including the ground state. Comparison with available thermochemical data is very good, supporting the applied methodology. The reaction, H3(+) + O4→ O4H(+) + H2, was found to be exothermic ΔH = -19.4 kcal mol(-1) and therefore, it is proposed that the product in the singlet state could be formed in the interstellar medium (ISM) via collision processes. To aid in its laboratory or radioastronomy detection in the interstellar medium we determined spectroscopic fingerprints. It is estimated for the most stable geometry of O4H(+) dipole allowed electronic transitions in the visible region at 429 nm and 666 nm, an intense band at 1745 cm(-1) in the infrared and signals at 40.6, 81.2 and 139.2 GHz in the microwave region at 10, 50 and 150 K respectively, relevant for detection in the ISM. PMID:26028209

  1. FIRST SPECTROSCOPIC IMAGING OBSERVATIONS OF THE SUN AT LOW RADIO FREQUENCIES WITH THE MURCHISON WIDEFIELD ARRAY PROTOTYPE

    SciTech Connect

    Oberoi, Divya; Matthews, Lynn D.; Lonsdale, Colin J.; Benkevitch, Leonid; Cairns, Iver H.; Lobzin, Vasili; Emrich, David; Wayth, Randall B.; Arcus, Wayne; Morgan, Edward H.; Williams, Christopher; Prabu, T.; Vedantham, Harish; Williams, Andrew; White, Stephen M.; Allen, G.; Barnes, David; Bernardi, Gianni; Bowman, Judd D.; Briggs, Frank H.

    2011-02-20

    We present the first spectroscopic images of solar radio transients from the prototype for the Murchison Widefield Array, observed on 2010 March 27. Our observations span the instantaneous frequency band 170.9- 201.6 MHz. Though our observing period is characterized as a period of 'low' to 'medium' activity, one broadband emission feature and numerous short-lived, narrowband, non-thermal emission features are evident. Our data represent a significant advance in low radio frequency solar imaging, enabling us to follow the spatial, spectral, and temporal evolution of events simultaneously and in unprecedented detail. The rich variety of features seen here reaffirms the coronal diagnostic capability of low radio frequency emission and provides an early glimpse of the nature of radio observations that will become available as the next generation of low-frequency radio interferometers come online over the next few years.

  2. A study of non-Keplerian velocities in observations of spectroscopic binary stars

    NASA Astrophysics Data System (ADS)

    Hearnshaw, J. B.; Komonjinda, Siramas; Skuljan, J.; Kilmartin, P. M.

    2012-11-01

    This paper presents an orbital analysis of six southern single-lined spectroscopic binary systems. The systems selected were shown to have circular or nearly circular orbits (e < 0.1) from earlier published solutions of only moderate precision. The purpose was to obtain high-precision orbital solutions in order to investigate the presence of small non-Keplerian velocity effects in the data and hence the reality of the small eccentricities found for most of the stars. The Hercules spectrograph and 1-m McLellan telescope at Mt John Observatory, New Zealand, were used to obtain over 450 CCD spectra between 2004 October and 2007 August. Radial velocities were obtained by cross-correlation. These data were used to achieve high-precision orbital solutions for all the systems studied, sometimes with solutions up to about 50 times more precise than those from the earlier literature. However, the precision of the solutions is limited in some cases by the rotational velocity or chromospheric activity of the stars. The data for the six binaries analysed here are combined with those for six stars analysed earlier by Komonjinda, Hearnshaw and Ramm. We have performed tests using the prescription of Lucy on all 12 binaries, and conclude that, with one exception, none of the small eccentricities found by fitting Keplerian orbits to the radial-velocity data can be supported. Instead we conclude that small non-Keplerian effects, which are clearly detectable for six of our stars, make impossible the precise determination of spectroscopic binary orbital eccentricities for many late-type stars to better than about 0.03 in eccentricity, unless the systematic perturbations are also carefully modelled. The magnitudes of the non-Keplerian velocity variations are given quantitatively.

  3. Culture and Influence in Multisite Evaluation

    ERIC Educational Resources Information Center

    Kirkhart, Karen E.

    2011-01-01

    Understanding the influence of multisite evaluation requires careful consideration of cultural context. The author illustrates dimensions of influence and culture with excerpts from four National Science Foundation evaluation case studies and summarizes what influence teaches everyone about culture and what culture teaches everyone about…

  4. Multisite functional connectivity MRI classification of autism: ABIDE results

    PubMed Central

    Nielsen, Jared A.; Zielinski, Brandon A.; Fletcher, P. Thomas; Alexander, Andrew L.; Lange, Nicholas; Bigler, Erin D.; Lainhart, Janet E.; Anderson, Jeffrey S.

    2013-01-01

    Background: Systematic differences in functional connectivity MRI metrics have been consistently observed in autism, with predominantly decreased cortico-cortical connectivity. Previous attempts at single subject classification in high-functioning autism using whole brain point-to-point functional connectivity have yielded about 80% accurate classification of autism vs. control subjects across a wide age range. We attempted to replicate the method and results using the Autism Brain Imaging Data Exchange (ABIDE) including resting state fMRI data obtained from 964 subjects and 16 separate international sites. Methods: For each of 964 subjects, we obtained pairwise functional connectivity measurements from a lattice of 7266 regions of interest covering the gray matter (26.4 million “connections”) after preprocessing that included motion and slice timing correction, coregistration to an anatomic image, normalization to standard space, and voxelwise removal by regression of motion parameters, soft tissue, CSF, and white matter signals. Connections were grouped into multiple bins, and a leave-one-out classifier was evaluated on connections comprising each set of bins. Age, age-squared, gender, handedness, and site were included as covariates for the classifier. Results: Classification accuracy significantly outperformed chance but was much lower for multisite prediction than for previous single site results. As high as 60% accuracy was obtained for whole brain classification, with the best accuracy from connections involving regions of the default mode network, parahippocampaland fusiform gyri, insula, Wernicke Area, and intraparietal sulcus. The classifier score was related to symptom severity, social function, daily living skills, and verbal IQ. Classification accuracy was significantly higher for sites with longer BOLD imaging times. Conclusions: Multisite functional connectivity classification of autism outperformed chance using a simple leave-one-out classifier

  5. Multisite Reliability of Cognitive BOLD Data

    PubMed Central

    Brown, Gregory G.; Mathalon, Daniel H.; Stern, Hal; Ford, Judith; Mueller, Bryon; Greve, Douglas N.; McCarthy, Gregory; Voyvodic, Jim; Glover, Gary; Diaz, Michele; Yetter, Elizabeth; Burak Ozyurt, I.; Jorgensen, Kasper W.; Wible, Cynthia G.; Turner, Jessica A.; Thompson, Wesley K.; Potkin, Steven G.

    2010-01-01

    Investigators perform multi-site functional magnetic resonance imaging studies to increase statistical power, to enhance generalizability, and to improve the likelihood of sampling relevant subgroups. Yet undesired site variation in imaging methods could off-set these potential advantages. We used variance components analysis to investigate sources of variation in the blood oxygen level dependent (BOLD) signal across four 3T magnets in voxelwise and region of interest (ROI) analyses. Eighteen participants traveled to four magnet sites to complete eight runs of a working memory task involving emotional or neutral distraction. Person variance was more than 10 times larger than site variance for five of six ROIs studied. Person-by-site interactions, however, contributed sizable unwanted variance to the total. Averaging over runs increased between-site reliability, with many voxels showing good to excellent between-site reliability when eight runs were averaged and regions of interest showing fair to good reliability. Between-site reliability depended on the specific functional contrast analyzed in addition to the number of runs averaged. Although median effect size was correlated with between-site reliability, dissociations were observed for many voxels. Brain regions where the pooled effect size was large but between-site reliability was poor were associated with reduced individual differences. Brain regions where the pooled effect size was small but between-site reliability was excellent were associated with a balance of participants who displayed consistently positive or consistently negative BOLD responses. Although between-site reliability of BOLD data can be good to excellent, acquiring highly reliable data requires robust activation paradigms, ongoing quality assurance, and careful experimental control. PMID:20932915

  6. Bias and Bias Correction in Multisite Instrumental Variables Analysis of Heterogeneous Mediator Effects

    ERIC Educational Resources Information Center

    Reardon, Sean F.; Unlu, Fatih; Zhu, Pei; Bloom, Howard S.

    2014-01-01

    We explore the use of instrumental variables (IV) analysis with a multisite randomized trial to estimate the effect of a mediating variable on an outcome in cases where it can be assumed that the observed mediator is the only mechanism linking treatment assignment to outcomes, an assumption known in the IV literature as the exclusion restriction.…

  7. Bias and Bias Correction in Multi-Site Instrumental Variables Analysis of Heterogeneous Mediator Effects

    ERIC Educational Resources Information Center

    Reardon, Sean F.; Unlu, Faith; Zhu, Pei; Bloom, Howard

    2013-01-01

    We explore the use of instrumental variables (IV) analysis with a multi-site randomized trial to estimate the effect of a mediating variable on an outcome in cases where it can be assumed that the observed mediator is the only mechanism linking treatment assignment to outcomes, as assumption known in the instrumental variables literature as the…

  8. Near Infrared photometric and spectroscopic observations of the bright optical transient J212444.87+321738.3

    NASA Astrophysics Data System (ADS)

    Mondal, Soumen; Das, Ramkrishna; Ashok, N. M.; Banerjee, D. P. K.; Dutta, Somnath; Ghosh, Supriyo; Mondal, Anindita

    2013-04-01

    We report near infrared JHK-band photometry and spectroscopic observations of the recently reported bright optical transient J212444.87+321738.3 using the Near-IR Imager cum spectrograph (NICMOS-3) installed on the Mount Abu 1.2-m telescope of the Physical Research Laboratory, India following the outburst announcement by Tiurina et al. in ATel #4888. The photometric observations were carried out on 2013 March 21.020 UT and 23.010 UT yielding magnitudes of J = 5.85 +/- 0.06, H = 4.47 +/- 0.06, K = 3.77 +/- 0.05; and J= 5.64 +/- 0.04, H= 4.48 +/- 0.04, K = 3.77 +/- 0.03 respectively.

  9. Thermal treatment effects imposed on solid DNA cationic lipid complex with hexadecyltrimethylammonium chloride, observed by variable angle spectroscopic ellipsometry

    SciTech Connect

    Nizioł, Jacek

    2014-12-21

    DNA cationic lipid complexes are materials of properties required for applications in organic electronics and optoelectronics. Often, their thermal stability demonstrated by thermogravimetry is cited in the literature as important issue. However, little is known about processes occurring in heated solid DNA cationic lipid complexes. In frame of this work, thin films of Deoxyribonucleic acid-hexadecyltrimethylammonium chloride (DNA-CTMA) were deposited on silicon wafers. Samples were thermally annealed, and simultaneously, their optical functions were measured by spectroscopic ellipsometry. At lower temperatures, thermal expansion coefficient of solid DNA-CTMA was negative, but at higher temperatures positive. Thermally induced modification of absorption spectrum in UV-vis was observed. It occurred at a range of temperatures higher than this of DNA denaturation in solution. The observed phenomenon was irreversible, at least in time scale of the experiment (one day)

  10. Spectroscopic observations of bright and dark emission features on the night side of venus.

    PubMed

    Bell, J F; Crisp, D; Lucey, P G; Ozoroski, T A; Sinton, W M; Willis, S C; Campbell, B A

    1991-05-31

    Near-infrared spectra of a bright and a dark thermal emission feature on the night side of Venus have been obtained from 2.2 to 2.5 micrometers (microm) at a spectral resolution of 1200 to 1500. Both bright and dark features show numerous weak absorption bands produced by CO(2), CO, water vapor, and other gases. The bright feature (hot spot) emits more radiation than the dark feature (cold spot) throughout this spectral region, but the largest contrasts occur between 2.21 and 2.32 microm, where H(2)SO(4) clouds and a weak CO(2) band provide the only known sources of extinction. The contrast decreases by 55 to 65 percent at wavelengths longer than 2.34 microm, where CO, clouds, and water vapor also absorb and scatter upwelling radiation. This contrast reduction may provide direct spectroscopic evidence for horizontal variations in the water vapor concentrations in the Venus atmosphere at levels below the cloud tops. PMID:17842954

  11. Radial-velocity observations of pulsating stars with a new Poznan Spectroscopic Telescope

    NASA Astrophysics Data System (ADS)

    Dimitrow, W.

    2008-12-01

    We present results of radial velocity measurements of classical cepheids, δ Scuti and β Cephei stars. The spectra were obtained with Poznan Spectroscopic Telescope (PST). The telescope has been operating since August 2007. The PST is equipped with two 40cm diameter mirrors of Newtonian focus, connected by an optic fiber with an echelle spectrograph. The PSTs design aimed at the best cooperation with the spectrograph as well as limiting light looses. It allows us to measure radial velocity of stars as faint as 11.5 magnitudes. The peltier-liquid cooled CCD camera covers 64 echelle orders with spectral range from 4480 to 9250˚A. The dispersion of the obtained radial velocity measurements is on the level of 150 m/s. Echelle spectra reduction and RV measu- rements are performed with Image Reduction and Analysis Facility (IRAF). We have achived sufficient phase coverage for 28 And, γ Peg, Polaris and V440 Per. Further data acquirement for other pulsating stars is currently held.

  12. Multi-site, multivariate weather generator using maximum entropy bootstrap

    NASA Astrophysics Data System (ADS)

    Srivastav, Roshan K.; Simonovic, Slobodan P.

    2014-05-01

    Weather generators are increasingly becoming viable alternate models to assess the effects of future climate change scenarios on water resources systems. In this study, a new multisite, multivariate maximum entropy bootstrap weather generator (MEBWG) is proposed for generating daily weather variables, which has the ability to mimic both, spatial and temporal dependence structure in addition to other historical statistics. The maximum entropy bootstrap (MEB) involves two main steps: (1) random sampling from the empirical cumulative distribution function with endpoints selected to allow limited extrapolation and (2) reordering of the random series to respect the rank ordering of the original time series (temporal dependence structure). To capture the multi-collinear structure between the weather variables and between the sites, we combine orthogonal linear transformation with MEB. Daily weather data, which include precipitation, maximum temperature and minimum temperature from 27 years of record from the Upper Thames River Basin in Ontario, Canada, are used to analyze the ability of MEBWG based weather generator. Results indicate that the statistics from the synthetic replicates were not significantly different from the observed data and the model is able to preserve the 27 CLIMDEX indices very well. The MEBWG model shows better performance in terms of extrapolation and computational efficiency when compared to multisite, multivariate K-nearest neighbour model.

  13. Submillimeter Continuum Observations of the T Tauri Spectroscopic Binary GW Orionis

    NASA Astrophysics Data System (ADS)

    Mathieu, R. D.; Adams, F. C.; Fuller, G. A.; Jensen, E. L.

    1993-05-01

    We have used the James Clerk Maxwell Telescope to detect strong submillimeter (350 microns - 1100 microns) continuum emission from the classical T Tauri star GW Orionis. GW Ori is a spectroscopic binary with a period of 242 days and a separation of 1 AU (Mathieu, Adams and Latham, 1991, AJ 101, 2184; MAL). It is the first pre-main sequence short-period binary system to show submillimeter emission. The submillimeter luminosity is comparable to the largest among both T Tauri and Herbig Ae stars. The emission is confined within a radius of 5 arcsec (2000 AU). We show that the origin of the emission must be circumbinary. With an optically thin, isothermal approximation we place a lower limit of 0.1 M_⊙ on the mass of circumbinary material, assuming a maximum temperature of 150 K. Using the pure-disk models of MAL, we find disk masses between a few tenths of a solar mass and a few solar masses, depending on choice of submillimeter opacity. These values are a significant fraction of the total stellar mass (2.8 M_⊙ to 3.8 M_⊙, depending on inclination) and possibly comparable to the secondary mass alone (0.3 M_⊙ to 1.3 M_⊙). Our fluxes are inconsistent with the disk-envelope model of MAL, for typically adopted opacities. Other extended distributions of material need to be considered, particularly since GW Ori lies near the birthline. If the circumbinary material is in a disk, then the derived masses are sufficient to drive rapid evolution of the binary orbital elements, including exciting eccentricity into the orbit. As such, the low eccentricity of GW Ori (e=0.04+/-0.06) may indicate that the disk matter does not populate the strong resonances near the secondary. In addition, the case of GW Ori suggests that massive circumbinary disks can survive the binary formation process, placing constraints on the degree of disk consumption and/or replenishment (e.g., if formation is the result of disk instabilities) or circuminary disk disruption (e.g.,in a disk

  14. Optical Spectroscopic Observations of γ-Ray Blazar Candidates. III. The 2013/2014 Campaign in the Southern Hemisphere

    NASA Astrophysics Data System (ADS)

    Landoni, M.; Massaro, F.; Paggi, A.; D'Abrusco, R.; Milisavljevic, D.; Masetti, N.; Smith, H. A.; Tosti, G.; Chomiuk, L.; Strader, J.; Cheung, C. C.

    2015-05-01

    We report the results of our exploratory program carried out with the southern Astrophysical Research telescope aimed at associating counterparts and establishing the nature of the Fermi Unidentified γ-ray Sources (UGSs). We selected the optical counterparts of six UGSs from the Fermi catalog on the basis of our recently discovered tight connection between infrared and γ-ray emission found for the γ-ray blazars detected by the Wide-Field Infrared Survey Explorer in its all-sky survey. We perform for the first time a spectroscopic study of the low-energy counterparts of the Fermi UGSs, in the optical band, confirming the blazar-like nature of the whole sample. We also present new spectroscopic observations of six active galaxies of uncertain type associated with Fermi sources which appear to be BL Lac objects. Finally, we report the spectra collected for six known γ-ray blazars belonging to the Roma BZCAT that were obtained to establish their nature or better estimate their redshifts. Two interesting cases of high redshift and extremely luminous BL Lac objects (z ≥ 1.18 and z ≥ 1.02, based on the detection of Mg ii intervening systems) are also discussed. Based on observations obtained at the southern Astrophysical Research (SOAR) telescope, which is a joint project of the Ministério da Ciência, Tecnologia, e Inovação (MCTI) da República Federativa do Brasil, the U.S. National Optical Astronomy Observatory (NOAO), the University of North Carolina at Chapel Hill (UNC), and Michigan State University (MSU).

  15. Spectroscopic Observations of Steep Spectrum Narrow-Line Seyfert 1 Galaxies

    NASA Technical Reports Server (NTRS)

    Leighly, Karen

    1999-01-01

    ROSAT observations of narrow-line Seyfert 1s found consistently steep spectra and rapid variability, but ASCA observations show more diversity, very different to classical Seyfert 1s. However, in 3 NLS1s, ASCA finds common characteristics of these exciting new class of AGN (active galactic nuclei): a very strong high temperature soft excess, weak hard tail, a possible blue shifted ionized oxygen edge, and rapid large amplitude variability characterized by flares and quiescent periods. It is necessary to observe many more such objects in order to understand the physical processes underlying the different phenomenology in ASCA. ASCA observations of two NLS1s discovered by ROSAT's all sky survey were proposed and an observation of one of these objects, RX J0439-45, was awarded. The results of spectral and variability analysis are included in Leighly 1999ab, and preliminary results are found in Leighly 1998ab.

  16. Detection of High-Frequency Oscillations and Damping from Multi-slit Spectroscopic Observations of the Corona

    NASA Astrophysics Data System (ADS)

    Samanta, T.; Singh, J.; Sindhuja, G.; Banerjee, D.

    2016-01-01

    During the total solar eclipse of 11 July 2010, multi-slit spectroscopic observations of the solar corona were performed from Easter Island, Chile. To search for high-frequency waves, observations were taken at a high cadence in the green line at 5303 Å that is due to [Fe xiv] and the red line at 6374 Å that is due to [Fe x]. The data were analyzed to study the periodic variations in intensity, Doppler velocity, and line width using wavelet analysis. The data with high spectral and temporal resolution enabled us to study the rapid dynamical changes within coronal structures. We find that at certain locations, each parameter shows significant oscillation with periods ranging from 6 - 25 s. For the first time, we were able to detect damping of high-frequency oscillations with periods of about 10 s. If the observed damped oscillations are due to magnetohydrodynamic waves, then they can contribute significantly to the heating of the corona. From a statistical study we try to characterize the nature of the observed oscillations while considering the distribution of power in different line parameters.

  17. Time Series Spectroscopic and Photometric Observations of the Massive DAV BPM 37093

    NASA Astrophysics Data System (ADS)

    Nitta, Atsuko; Kepler, S. O.; Chene, Andre–Nicolas; Koester, D.; Provencal, J. L.; Sullivan, D. J.; Chote, Paul; Safeko, Ramotholo; Kanaan, Antonio; Romero, Alejandra; Corti, Mariela; Corti, Mariela; Kilic, Mukremin; Winget, D. E.

    2015-06-01

    BPM 37093 was the first of only a handful of massive (1.05+/-0.05 M⊙; Bergeron 2004;Koester & Allard 2000) white dwarf pulsators discovered (Kanaan et al. 1992). These stars are particularly interesting because the crystallized mass-fraction as a function of mass and temperature is poorly constrained by observation, yet this process adds 1-2 Gyr uncertainty in ages of the oldest white dwarf stars observed and hence, in the ages of associations that contain them (Abrikosov 1960; Kirzhnits 1960; Salpeter 1961). Last year, we discovered that ESO uses BPM 37093 as a standard star and extracted corresponding spectra from the public archive. The data suggested a large variation in the observed hydrogen line profiles that could potentially be due to pulsations, but the measurement did not reach a detection-quality threshold. To further explore this possibility, though, we obtained 4hrs of continuous time series spectroscopy of BPM 37093 with Gemini in the Northern Spring of 2014. We present our preliminary results from these data along with those from the accompanying time series photometric observations we gathered from Mt. John (New Zealand), South African Astronomical Observatory (SAAO), Panchromatic Robotic optical Monitoring and Polarimetry Telescopes (PROMPT) in Chile, and Complejo Astronomico El Leoncito (Argentina) to support the Gemini observations.

  18. Non-LTE Inversion of Spectropolarimetric and Spectroscopic Observations of a Small Active-region Filament Observed at the VTT

    NASA Astrophysics Data System (ADS)

    Schwartz, P.; Balthasar, H.; Kuckein, C.; Koza, J.; Gömöry, P.; Rybák, J.; Kučera, A.; Heinzel, P.

    2016-04-01

    An active region mini-filament was observed by VTT simultaneously in the HeI 10 830 Å triplet by the TIP 1 spectropolarimeter, in Hα by the TESOS Fabry-Pérot interferometer, and in Ca II 8542 Å by the VTT spectrograph. The spectropolarimetric data were inverted using the HAZEL code and Hα profiles were modelled solving a NLTE radiative transfer in a simple isobaric and isothermal 2D slab irradiated both from bottom and sides. It was found that the mini-filament is composed of horizontal fluxtubes, along which the cool plasma of T˜10 000 K can flow by very large - even supersonic - velocities.

  19. Spectroscopic observations of the Uranus' satellite Miranda in Near-IR

    NASA Astrophysics Data System (ADS)

    Gourgeot, F.; Dumas, C.; Merlin, F.; Vernazza, P.; Alvarez-Candal, A.

    2013-09-01

    We present new Near-IR spectra of the Uranus' icy satellite Miranda. This body is probably the most remarkable of all satellites of Uranus, displaying series of surface features such as faults, craters and largescale upwelling, remnant of a geologically very active past. The observations were performed first at the Palomar Observatory with the PHARO instrument (Palomar High Angular Resolution Observer) and then at the Mauna Kea Observatory with SpeX instrument based on the IRTF (Infra-Red Telescope Facility). Water ice is clearly visible in K-band (large 2.0 μm absorption band) and crystalline water ice (at 1.65 μm) seems to cover the most part of the satellite's surface. We focused the study in H band on the 1.42-1.72 μm range at observations dates corresponding to the leading and trailing hemispheres of Miranda. Contrary to the other outer Uranus' moons (Grundy et al. 2006), we did not found any significative differences between both hemispheres in this spectral range. We also studied the possible presence of volatiles like ammonia hydrate and do not exclude the possible presence of a tiny 2.22 μm band yet observed by Bauer et al. 2002. No significant features of carbon dioxide were identified on any spectra. We performed spectral models, based on bi-hemispherical reflectance theory (Hapke 1993) in order to obtain more details on the chemical compounds possibly present on the surface of this Uranian satellite.

  20. Inferential monitoring of chlorinated solvents through Raman spectroscopic observation of the vibrational modes of water.

    PubMed

    Sinfield, Joseph V; Monwuba, Chike

    2016-02-01

    Recent improvements in diode laser, fiber optic, and data acquisition technology have rejuvenated interest in field applications of Raman spectroscopy in a wide range of settings. One such application involves the observation of chlorinated solvents to facilitate the practice of "monitored natural attenuation." In this context, this manuscript focuses on means to improve the sensitivity of in-situ Raman analysis of chlorinated solvents. In particular, the work explores the performance limits of a Time-Resolved Raman Spectroscopy (TRRS) system employed to observe chlorinated solvents in aqueous samples via laboratory tests conducted on both liquid standards of trichloroethylene (TCE) and simulated biodegraded field samples. Quantitative assessment of TCE in solution is carried out through both direct observation of TCE Raman functional groups (381 cm(-1) (δ skeletal), 840 cm(-1) (νCCl) and 1242 cm(-1) (δCH)) and indirect observation of the broad OH stretching (2700-3800 cm(-1)) Raman modes of water. Results from tests on simple solutions show that the TRRS system can detect TCE at aqueous concentrations as low as 70 ppm by directly monitoring the 381 cm(-1) TCE line, whereas observation of the OH stretching line of water (3393 cm(-1)) provides an indirect indication of TCE presence with nearly a 9× improvement in detection level. This unique and counterintuitive mechanism to detect the presence of chlorinated compounds in solution takes advantage of the influence of chlorine on the vibrational modes of water. This influence, which is believed to be attributed to the formation of hydrogen bonds and their resultant interactions with the solvation shell, may serve as a more sensitive and robust indication of the presence of aggregate chlorinated solvent contamination in aqueous systems. Tests performed on simulated biodegraded field samples demonstrate that the indirect detection mechanism is apparent even in complex samples representative of typical field

  1. The composition of M-type asteroids II: Synthesis of spectroscopic and radar observations

    NASA Astrophysics Data System (ADS)

    Neeley, J. R.; Clark, B. E.; Ockert-Bell, M. E.; Shepard, M. K.; Conklin, J.; Cloutis, E. A.; Fornasier, S.; Bus, S. J.

    2014-08-01

    This work updates and expands on results of our long-term radar-driven observational campaign of main-belt asteroids (MBAs) focused on Bus-DeMeo Xc- and Xk-type objects (Tholen X and M class asteroids) using the Arecibo radar and NASA Infrared Telescope Facilities (Ockert-Bell, M.E., Clark, B.E., Shepard, M.K., Rivkin, A.S., Binzel, R.P., Thomas, C.A., DeMeo, F.E., Bus, S.J., Shah, S. [2008]. Icarus 195, 206-219; Ockert-Bell, M.E., Clark, B.E., Shepard, M.K., Issacs, R.A., Cloutis, E.A., Fornasier, S., Bus, S.J. [2010]. Icarus 210, 674-692; Shepard, M.K. et al. [2008a]. Icarus 193, 20-38; Shepard, M.K. et al. [2008b]. Icarus 195, 184-205; Shepard, M.K. et al. [2010]. Icarus 215, 547-551). Eighteen of our targets were near-simultaneously observed with radar and those observations are described in Shepard et al. (Shepard, M.K. et al. [2010]. Icarus 215, 547-551). We combine our near-infrared data with available visible wavelength data for a more complete compositional analysis of our targets. Compositional evidence is derived from our target asteroid spectra using two different methods, a χ2 search for spectral matches in the RELAB database and parametric comparisons with meteorites. We present four new methods of parametric comparison, including discriminant analysis. Discriminant analysis identifies meteorite type with 85% accuracy. This paper synthesizes the results of these two analog search algorithms and reconciles those results with analogs suggested from radar data (Shepard, M.K. et al. [2010]. Icarus 215, 547-551). We have observed 29 asteroids, 18 in conjunction with radar observations. For eighteen out of twenty-nine objects observed (62%) our compositional predictions are consistent over two or more methods applied. We find that for our Xc and Xk targets the best fit is an iron meteorite for 34% of the samples. Enstatite chondrites were best fits for 6 of our targets (21%). Stony-iron meteorites were best fits for 2 of our targets (7%). A discriminant

  2. Evidence for CO in Jupiter's atmosphere from airborne spectroscopic observations at 5 microns

    NASA Technical Reports Server (NTRS)

    Larson, H. P.; Fink, U.; Treffers, R. R.

    1978-01-01

    High-altitude (12.4 km) spectra of Jupiter recorded at the Kuiper Airborne Observatory are analyzed for the presence of CO absorption lines. A line-by-line comparison of Jupiter's spectrum with that of carbon monoxide is presented, as well as a correlation analysis that includes the influence of other gases present in Jupiter's atmosphere (CH4, NH3, H2O, PH3, and GeH4). The resulting evidence points strongly to the presence of carbon monoxide in Jupiter's atmosphere, thus strengthening Beer's evidence for it. Possible explanations for the existence and observability of Jovian CO, including convection from hotter, deeper layers or decomposition of organic molecules, are explored. A recent suggestion that the Jovian CO is restricted to stratospheric levels is not supported by the observations.

  3. SPECTROSCOPIC OBSERVATIONS OF PLANETARY NEBULAE IN THE NORTHERN SPUR OF M31

    SciTech Connect

    Fang, X.; Liu, X.-W.; Zhang, Y.; Garcia-Benito, R.

    2013-09-10

    We present spectroscopy of three planetary nebulae (PNe) in the Northern Spur of the Andromeda galaxy (M31) obtained with the Double Spectrograph on the 5.1 m Hale Telescope at the Palomar Observatory. The samples were selected from the observations of Merrett et al. Our purpose is to investigate the formation of the substructures of M31 using PNe as a tracer of chemical abundances. The [O III] {lambda}4363 line is detected in the spectra of two objects, enabling temperature determinations. Ionic abundances are derived from the observed collisionally excited lines, and elemental abundances of nitrogen, oxygen, neon, sulfur, and argon are estimated. We study the correlations between oxygen and the {alpha}-element abundance ratios using our sample and the M31 disk and bulge PNe from the literature. In one of the three PNe, we observed a relatively higher oxygen abundance compared to the disk sample of M31 at similar galactocentric distances. The results of at least one of the three Northern Spur PNe might be in line with the proposed possible origin of the Northern Spur substructure of M31, i.e., the Northern Spur is connected to the Southern Stream and both substructures comprise the tidal debris of the satellite galaxies of M31.

  4. Impact of Spectroscopic Line Parameters on Carbon Monoxide Column Density Retrievals from Shortwave Infrared Nadir Observations

    NASA Astrophysics Data System (ADS)

    Schmidt, Denise; Gimeno Garcia, Sebastian; Schreier, Franz; Lichtenberg, Gunter

    2015-06-01

    Among the various input data required for the retrieval of atmospheric state parameters from infrared remote sensing observations molecular spectroscopy line data have a central role, because their quality is critical for the quality of the final product. Here we discuss the impact of the line parameters on vertical column densities (VCD) estimated from short wave infrared nadir observations. Using BIRRA (the Beer InfraRed Retrieval Algorithm) comprising a line-by-line radiative transfer code (forward model) and a separable nonlinear least squares solver for inversion we retrieve carbon monoxide from observations of SCIAMACHY aboard Envisat. Retrievals using recent versions of HITRAN und GEISA have been performed and the results are compared in terms of residual norms, molecular density scaling factors, their corresponding errors, and the final VCD product. The retrievals turn out to be quite similar for all three databases, so a definite recommendation in favor of one of these databases is difficult for the considered spectral range around 2:3 μm . Nevertheless, HITRAN 2012 appears to be advantageous when evaluating the different quality criteria.

  5. The composition of M-type asteroids: Synthesis of spectroscopic and radar observations

    NASA Astrophysics Data System (ADS)

    Ockert-Bell, M. E.; Clark, B. E.; Shepard, M. K.; Isaacs, R. A.; Cloutis, E. A.; Fornasier, S.; Bus, S. J.

    2010-12-01

    We have conducted a radar-driven observational campaign of 22 main-belt asteroids (MBAs) focused on Bus-DeMeo Xc- and Xk-type objects (Tholen X and M class asteroids) using the Arecibo radar and NASA Infrared Telescope Facilities (IRTF). Sixteen of our targets were near-simultaneously observed with radar and those observations are described in a companion paper (Shepard, M.K., and 19 colleagues [2010]. Icarus, in press). We find that most of the highest metal-content asteroids, as suggested by radar, tend to exhibit silicate absorption features at both 0.9 and 1.9 μm, and the lowest metal-content asteroids tend to exhibit either no bands or only the 0.9 μm band. Eleven of the asteroids were observed at several rotational longitudes in the near-infrared and significant variations in continuum slope were found for nine in the spectral regions 1.1-1.45 μm and 1.6-2.3 μm. We utilized visible wavelength data (Bus, S.J., Binzel, R.P. [2002b]. Icarus 158, 146-177; Fornasier, S., Clark, B.E., Dotto, E., Migliorini, A., Ockert-Bell, M., Barucci, M.A. [2010]. Icarus 210, 655-673.) for a more complete compositional analysis of our targets. Compositional evidence is derived from our target asteroid spectra using two different methods: (1) a χ2 search for spectral matches in the RELAB database, and (2) parametric comparisons with meteorites. This paper synthesizes the results of the RELAB search and the parametric comparisons with compositional suggestions based on radar observations. We find that for six of the seven asteroids with the highest iron abundances, our spectral results are consistent with the radar evidence (16 Psyche, 216 Kleopatra, 347 Pariana, 758 Mancunia, 779 Nina, and 785 Zwetana). Three of the seven asteroids with the lowest metal abundances, our spectral results are consistent with the radar evidence (21 Lutetia, 135 Hertha, 497 Iva). The remaining seven asteroids (22 Kalliope, 97 Klotho, 110 Lydia, 129 Antigone, 224 Oceana, 678 Fredegundis, and 771

  6. SULFUR CHEMISTRY. Gas phase observation and microwave spectroscopic characterization of formic sulfuric anhydride.

    PubMed

    Mackenzie, Rebecca B; Dewberry, Christopher T; Leopold, Kenneth R

    2015-07-01

    We report the observation of a covalently bound species, formic sulfuric anhydride (FSA), that is produced from formic acid and sulfur trioxide under supersonic jet conditions. FSA has been structurally characterized by means of microwave spectroscopy and further investigated by using density functional theory and ab initio calculations. Theory indicates that a π2 + π2 + σ2 cycloaddition reaction between SO3 and HCOOH is a plausible pathway to FSA formation and that such a mechanism would be effectively barrierless. We speculate on the possible role that FSA may play in the Earth's atmosphere. PMID:26138972

  7. In Situ Spectroscopic Observation of Activation and Transformation of Tantalum Suboxides

    SciTech Connect

    Wang, Ke; Liu, Zhi; Cruz, Tirma Herranz; Salmeron, Miquel; Liang, Hong

    2009-12-16

    Using ambient pressure X-ray Photoelectron Spectroscopy (AP-XPS), we were able to observe the process of oxidation of tantalum with different morphological parameters. Being able to trace surface evolution during oxidation, we evaluated activation energy of oxidation under the influence of strain and grain boundaries. It was found that the metal oxidized through three different stages and there was a transition stage where the phase transformation from suboxides to the equilibrium state of pentoxide. The applied stress and surface defects reduced the activation energy oxidation.

  8. High-dispersion Spectroscopic Observations Of 8P/Tuttle With VLT/CRIRES

    NASA Astrophysics Data System (ADS)

    Kobayashi, Hitomi; Bockelee-Morvan, D.; Dello Russo, N.; Kawakita, H.; Verback, R. J.; Weaver, H.; Jehin, E.; Manfroid, J.; Smette, A.; Cochran, A.; Hutsemekers, D.; Schulz, R.; Stuwe, J.; Weiler, M.; Zucconi, J.; Arpigny, C.; Biver, N.; Crovisier, J.; Magain, P.; Rauer, H.; Sana, H.

    2008-09-01

    We present near-infrared observations of organic molecules in comet 8P/Tuttle. Comet 8P/Tuttle is a Halley-type comet and its last perihelion was in early January 2008. Our observations were carried out on January 28 and February 4 using CRIRES (CRyogenic high-resolution InfraRed Echelle Spectrograph) at the Very Large Telescope (VLT). We used a 0.2" slit which provided a spectral resolving power of 80,000. We detected H2O, OH, HCN, C2H2 on Jan 28, and H2O, OH, CH4, C2H6, and CH3OH on Feb 4. We find that 8P/Tuttle is depleted in HCN, C2H2 and C2H6 relative to H2O compared with most other Oort cloud comets studied to date. Perhaps these depletions suggest that 8P/Tuttle formed in a different region from most Oort cloud comets, but it is also possible that the depletions are caused by repeated passages through the inner solar system.

  9. The "Cool Algol" BD+05 706 : Photometric observations of a new eclipsing double-lined spectroscopic binary

    NASA Astrophysics Data System (ADS)

    Marschall, L. A.; Torres, G.; Neuhauser, R.

    1998-05-01

    BVRI Observations of the star BD+05 706, carried out between January, 1997, and April 1998 using the 0.4m reflector and Photometrics CCD camera at the Gettysburg College Observatory, show that the star is an eclipsing binary system with a light curve characteristic of a class of semi-detached binaries known as the "cool Algols". These results are in good agreement with the previous report of BD+05 706 as a cool Algol by Torres, Neuhauser, and Wichmann,(Astron. J., 115, May 1998) who based their classification on the strong X-ray emission detected by Rosat and on a series of spectroscopic observations of the radial velocities of both components of the system obtained at the Oak Ridge Observatory, the Fred L. Whipple Observatory, and the Multiple Mirror Telescope. Only 10 other examples of cool Algols are known, and the current photometric light curve, together with the radial velocity curves obtained previously, allows us to derive a complete solution for the physical parameters of each component, providing important constraints on models for these interesting systems.

  10. Imaging and spectroscopic observations of a filament channel and the implications for the nature of counter-streamings

    SciTech Connect

    Chen, P. F.; Fang, C.; Harra, L. K.

    2014-03-20

    The dynamics of a filament channel are observed with imaging and spectroscopic telescopes before and during the filament eruption on 2011 January 29. The extreme ultraviolet (EUV) spectral observations reveal that there are no EUV counterparts of the Hα counter-streamings in the filament channel, implying that the ubiquitous Hα counter-streamings found by previous research are mainly due to longitudinal oscillations of filament threads, which are not in phase between each other. However, there exist larger-scale patchy counter-streamings in EUV along the filament channel from one polarity to the other, implying that there is another component of unidirectional flow (in the range of ±10 km s{sup –1}) inside each filament thread in addition to the implied longitudinal oscillation. Our results suggest that the flow direction of the larger-scale patchy counter-streaming plasma in the EUV is related to the intensity of the plage or active network, with the upflows being located at brighter areas of the plage and downflows at the weaker areas. We propose a new method to determine the chirality of an erupting filament on the basis of the skewness of the conjugate filament drainage sites. This method suggests that the right-skewed drainage corresponds to sinistral chirality, whereas the left-skewed drainage corresponds to dextral chirality.

  11. SHRINE: Enabling Nationally Scalable Multi-Site Disease Studies

    PubMed Central

    McMurry, Andrew J.; Murphy, Shawn N.; MacFadden, Douglas; Weber, Griffin; Simons, William W.; Orechia, John; Bickel, Jonathan; Wattanasin, Nich; Gilbert, Clint; Trevvett, Philip; Churchill, Susanne; Kohane, Isaac S.

    2013-01-01

    Results of medical research studies are often contradictory or cannot be reproduced. One reason is that there may not be enough patient subjects available for observation for a long enough time period. Another reason is that patient populations may vary considerably with respect to geographic and demographic boundaries thus limiting how broadly the results apply. Even when similar patient populations are pooled together from multiple locations, differences in medical treatment and record systems can limit which outcome measures can be commonly analyzed. In total, these differences in medical research settings can lead to differing conclusions or can even prevent some studies from starting. We thus sought to create a patient research system that could aggregate as many patient observations as possible from a large number of hospitals in a uniform way. We call this system the ‘Shared Health Research Information Network’, with the following properties: (1) reuse electronic health data from everyday clinical care for research purposes, (2) respect patient privacy and hospital autonomy, (3) aggregate patient populations across many hospitals to achieve statistically significant sample sizes that can be validated independently of a single research setting, (4) harmonize the observation facts recorded at each institution such that queries can be made across many hospitals in parallel, (5) scale to regional and national collaborations. The purpose of this report is to provide open source software for multi-site clinical studies and to report on early uses of this application. At this time SHRINE implementations have been used for multi-site studies of autism co-morbidity, juvenile idiopathic arthritis, peripartum cardiomyopathy, colorectal cancer, diabetes, and others. The wide range of study objectives and growing adoption suggest that SHRINE may be applicable beyond the research uses and participating hospitals named in this report. PMID:23533569

  12. Spectroscopic observation of jet-cooled 2,5-dichlorobenzyl radical generated by corona discharge

    NASA Astrophysics Data System (ADS)

    Yi, Eun Hye; Yoon, Young Wook; Lee, Sang Kuk

    2014-07-01

    Vibronically excited but jet-cooled 2,5-dichlorobenzyl radical was generated from 2,5-dichlorotoluene precursor in a large excess of helium carrier gas, from which the visible vibronic emission spectrum was recorded. From an analysis of the spectrum observed, it was found that the origin band shows larger shift to red than those expected from mono-substitutions, which has been discussed in terms of orientation of substituents. Also, the electronic energy of the D1 → D0 transition and vibrational mode frequencies at the ground electronic state of the 2,5-dichlorobenzyl radical were determined in comparison with the known vibrational data of precursor and ab initio calculations.

  13. Spectroscopic Observation of Resonant Electric Dipole-Dipole Interactions between Cold Rydberg Atoms

    NASA Astrophysics Data System (ADS)

    Afrousheh, K.; Bohlouli-Zanjani, P.; Vagale, D.; Mugford, A.; Fedorov, M.; Martin, J. D.

    2004-11-01

    Resonant electric dipole-dipole interactions between cold Rydberg atoms were observed using microwave spectroscopy. Laser-cooled 85Rb atoms in a magneto-optical trap were optically excited to 45d5/2 Rydberg states using a pulsed laser. A microwave pulse transferred a fraction of these Rydberg atoms to the 46p3/2 state. A second microwave pulse then drove atoms in the 45d5/2 state to the 46d5/2 state, and was used as a probe of interatomic interactions. The spectral width of this two-photon probe transition was found to depend on the presence of the 46p3/2 atoms, and is due to the resonant electric dipole-dipole interaction between 45d5/2 and 46p3/2 Rydberg atoms.

  14. Herschel spectroscopic observations of Zw 049.057 and Arp 299

    NASA Astrophysics Data System (ADS)

    Falstad, Niklas; Aalto, Susanne; González-Alfonso, Eduardo

    2015-08-01

    Luminous infrared galaxies (LIRGs) are extreme examples of star-forming galaxies or galaxies with active galactic nuclei (AGN), often interacting or merging systems, whose high infrared luminosities are powered by their intense star formation or AGN activity. Through studying molecular species that are mainly excited by warm dust emission (i.e. OH, H2O) it is possible to probe the nuclear source of far-IR radiation and gain insights in its physical conditions and chemistry.We present the results and analysis of Herschel observations of the compact obscured nucleus in the extremely H2O luminous LIRG Zw 049.057. We model the H2O and OH lines and continuum using a spherically symmetric radiative transfer code. We find that the far-IR absorption lines are primarily formed in a Compton-thick warm (Tdust>100 K) core with high columns of H2O and OH (similar to the nuclear regions of the ULIRG Arp 220). We also find an enhancement of 18O in the core component, suggesting that the ISM has been enriched by ejecta from massive stars.One of the low excited H2O lines exhibit an emission feature extending up to 500 km/s, suggesting an outflow. At the same time, we find a prominent infall signature in the [O I] 63 µm line, implying that the gas reservoir in the central region of Zw 049.057 is being replenished. The presence of both outflowing and infalling gas suggests that the nucleus is in a state of rapid evolution.We also present observations of the luminous merger Arp 299. This is another source with prominent H2O and OH lines, but preliminary results suggest that its nuclear activity is in a different evolutionary state compared to Zw 049.057.

  15. Extreme-Ultraviolet Spectroscopic Observation of Direct Coronal Heating During a C-Class Solar Flare

    NASA Technical Reports Server (NTRS)

    Brosius, Jeffrey W.

    2012-01-01

    With the Coronal Diagnostic Spectrometer operating in rapid cadence (9.8 s) stare mode during a C6.6 flare on the solar disk, we observed a sudden brightening of Fe xix line emission (formed at temperature T ˜ 8 MK) above the pre-flare noise without a corresponding brightening of emission from ions formed at lower temperatures, including He i (0.01 MK), Ov (0.25 MK), and Si xii (2 MK). The sudden brightening persisted as a plateau of Fe xix intensity that endured more than 11 minutes. The Fe xix emission at the rise and during the life of the plateau showed no evidence of significant bulk velocity flows, and hence cannot be attributed to chromospheric evaporation. However, the line width showed a significant broadening at the rise of the plateau, corresponding to nonthermal velocities of at least 89 km s-1 due to reconnection outflows or turbulence. During the plateau He i, Ov, and Si xii brightened at successively later times starting about 3.5 minutes after Fe xix, which suggests that these brightenings were produced by thermal conduction from the plasma that produced the Fe xix line emission; however, we cannot rule out the possibility that they were produced by a weak beam of nonthermal particles. We interpret an observed shortening of the Ov wavelength for about 1.5 minutes toward the middle of the plateau to indicate new upward motions driven by the flare, as occurs during gentle chromospheric evaporation; relative to a quiescent interval shortly before the flare, the Ov upward velocity was around -10 km s-1.

  16. Building a Community of Evaluation Practice within a Multisite Program

    ERIC Educational Resources Information Center

    Goodyear, Leslie K.

    2011-01-01

    New and novel uses of evaluation processes and findings are possible when a community of practice develops as evaluation stakeholders participate in multisite evaluations in multiple ways. Developing such communities takes advantage of what makes multisite evaluations special. This chapter uses the example of the Innovative Technology Experiences…

  17. A Mixed Methods Sampling Methodology for a Multisite Case Study

    ERIC Educational Resources Information Center

    Sharp, Julia L.; Mobley, Catherine; Hammond, Cathy; Withington, Cairen; Drew, Sam; Stringfield, Sam; Stipanovic, Natalie

    2012-01-01

    The flexibility of mixed methods research strategies makes such approaches especially suitable for multisite case studies. Yet the utilization of mixed methods to select sites for these studies is rarely reported. The authors describe their pragmatic mixed methods approach to select a sample for their multisite mixed methods case study of a…

  18. The Role of Involvement and Use in Multisite Evaluations

    ERIC Educational Resources Information Center

    Lawrenz, Frances; King, Jean A.; Ooms, Ann

    2011-01-01

    A cross-case analysis of four National Science Foundation (NSF) case studies identified both unique details and common themes related to promoting the use and influence of multisite evaluations. The analysis provided evidence of diverse evaluation use by stakeholders and suggested that people taking part in the multisite evaluations perceived…

  19. OH populations and temperatures from simultaneous spectroscopic observations of 25 bands

    NASA Astrophysics Data System (ADS)

    Noll, S.; Kausch, W.; Kimeswenger, S.; Unterguggenberger, S.; Jones, A. M.

    2015-04-01

    OH rotational temperatures are widely used to derive mesopause temperatures and their variations. Since most data sets are only based on a fixed set of lines of a single band, it is important to know possible systematic uncertainties related to the choice of lines. Therefore, a comprehensive study of as many OH bands as possible is desirable. For this purpose, astronomical echelle spectrographs at large telescopes are the most suitable instruments. They offer a wide wavelength coverage, relatively high spectral resolution, and high sensitivity. Moreover, since each ground-based astronomical observation has an imprint of the Earth's atmosphere, the data archives of large astronomical facilities are a treasure for atmospheric studies. For our project, we used archival data of the medium-resolution X-shooter echelle spectrograph operated by the European Southern Observatory at Cerro Paranal in Chile. The instrument can simultaneously observe all OH bands that are accessible from ground. We reduced and analysed a set of 343 high-quality spectra taken between 2009 and 2013 to measure OH line intensities and to derive rotational and vibrational temperatures of 25 bands between 0.58 and 2.24 μm. We studied the influence of the selected line set, OH band, upper vibrational level v', and the molecular data on the derived level populations and temperatures. The rotational temperature results indicate differences by several degrees depending on the selection. The temperatures for bands of even and odd v' show deviations which increase with v'. A study of the temporal variations revealed that the nocturnal variability pattern changes for v' from 2 to 9. In particular, the spread of temperatures tends to increase during the night, and the time of the minimum temperature depends on v'. The vibrational temperatures depend on the range of v' used for their determination, since the higher vibrational levels from 7 to 9 seem to be overpopulated compared to the lower levels. The

  20. Spectroscopic Coronal Observations During the Total Solar Eclipse of 11 July 2010

    NASA Astrophysics Data System (ADS)

    Voulgaris, A. G.; Gaintatzis, P. S.; Seiradakis, J. H.; Pasachoff, J. M.; Economou, T. E.

    2012-05-01

    The flash spectra of the solar chromosphere and corona were measured with a slitless spectrograph before, after, and during the totality of the solar eclipse of 11 July 2010, at Easter Island, Chile. This eclipse took place at the beginning of Solar Cycle 24, after an extended minimum of solar activity. The spectra taken during the eclipse show a different intensity ratio of the red and green coronal lines compared with those taken during the total solar eclipse of 1 August 2008, which took place toward the end of Solar Cycle 23. The characteristic coronal emission line of forbidden Fe xiv (5303 Å) was observed on the east and west solar limbs in four areas relatively symmetrically located with respect to the solar rotation axis. Subtraction of the continuum flash-spectrum background led to the identification of several extremely weak emission lines, including forbidden Ca xv (5694 Å), which is normally detected only in regions of very high excitation, e.g., during flares or above large sunspots. The height of the chromosphere was measured spectrophotometrically, using spectral lines from light elements and compared with the equivalent height of the lower chromosphere measured using spectral lines from heavy elements.

  1. Direct spectroscopic observation of multiple-charged-ion acceleration by an intense femtosecond-pulse laser.

    PubMed

    Zhidkov, A G; Sasaki, A; Tajima, T; Auguste, T; D'Olivera, P; Hulin, S; Monot, P; Faenov, A Y; Pikuz, T A; Skobelev, I Y

    1999-09-01

    We have observed evidence of the emission of energetic He-and H-like ions of fluorine more than 1 MeV produced via the optical field ionization (OFI) from a solid target irradiated by an intense I=(2-4)x10(18) W/cm(2) (60 fs, lambda=800 nm), obliquely incident p-polarized pulse laser. The measured blue wing of He(alpha), He(beta), and Ly(alpha) lines of fluorine shows a feature of the Doppler-shifted spectrum due to the self-similar ion expansion dominated by superthermal electrons with the temperature T(h) approximately 100 keV. Using a collisional particle-in-cell simulation, which incorporates the nonlocal-thermodynamic-equilibrium ionization including OFI, we have obtained the plasma temperature, line shape, and maximal energy of accelerated ions, which agree well with those determined from the experimental spectra. The red wing of ion spectra gives the temperature of bulk plasma electrons. PMID:11970139

  2. Direct spectroscopic observation of ion deceleration accompanying laser plasma-wall interaction

    NASA Astrophysics Data System (ADS)

    Renner, O.; Krouský, E.; Liska, R.; Šmíd, M.; Larroche, O.; Dalimier, E.; Rosmej, F. B.

    2010-08-01

    Interactions of plasma jets with solid surfaces are extensively studied in context with development of future fusion devices. In experiments carried out on the iodine laser system PALS, the energetic ions were produced at double-foil Al/Mg targets irradiated by one or two counter-propagating laser beams. The plasma jets from the rear surface of the laser-exploded Al foil streamed towards the Mg target representing the wall preheated by the action of the high-energy photons, particle and/or laser beams. Instead of being trapped by the cold secondary-target material, the forward-accelerated Al ions collided with the counter-propagating matter ejected from the wall. The environmental conditions in near-wall plasmas were analyzed with the high-resolution x-ray spectroscopy and temporally-resolved x-ray imaging. The deceleration of the incident Al ions in the near-wall region was directly observed and quantitatively characterized via Doppler shifts of the J-satellite from the Al Lya spectral group. The interaction scenario was modelled using the 2D arbitrary Lagrangian Eulerian hydrocode PALE and the multifluid code MULTIF.

  3. High-Dispersion Spectroscopic Observations of Comet C/2012 S1 (ISON) with the Subaru Telescope

    NASA Astrophysics Data System (ADS)

    Shinnaka, Yoshiharu; Kawakita, Hideyo; Nagashima, Masayoshi; Hitomi, Kobayashi; Decock, Alice; Jehin, Emmanuel; Boice, Daniel C.

    2014-11-01

    Comet C/2012 S1 (ISON) was one of the Oort cloud comets and dynamically new. This comet was broken at its perihelion passage on UT 2013 November 28.1 (at Rh ~ 17 solar radius). We observed the comet C/2012 S1 (ISON) on UT 2013 November 15 with the High Dispersion Spectrograph (HDS) mounted on the Subaru Telescope atop Mauna Kea, Hawaii. Its heliocentric and geocentric distances were 0.601 and 0.898 AU, respectively. We selected the slit size of 0”.5 x 9”.0 on the sky to achieve the spectral resolution of R = 72,000 from 550 to 830 nm. The total exposure time of comet C/2012 S1 (ISON) was 1200 seconds. We detected many emission lines caused from radicals (e.g., CN, C2, NH2), ions (H2O+), atoms ([OI] and Na I) and also many unidentified lines in the spectra. We report the (1) the ortho-to-para abundance ratios (OPRs) of water and ammonia estimated from the high-dispersion spectra of H2O+ and NH2, (2) the green-to-red line ratio of forbidden oxygen emissions, (3) the isotopic ratios of C2 (the carbon isotopic ratio from Swan band) and CN (the carbon and nitrogen isotopic ratios from red band), (4) the sodium-to-continuum ratio of comet C/2012 S1 (ISON).

  4. A multisite validity study of self-reported anesthesia outcomes.

    PubMed

    Walker, Peter; Pekmezaris, Renee; Lesser, Martin L; Nouryan, Christian N; Rosinia, Frank; Pratt, Kathy; LaVopa, Catherine

    2012-01-01

    The purpose of this study was to assess the validity of a multisite anesthesia voluntary adverse event reporting process. A data validation methodology was used through medical chart review on live records at 3 facilities (N = 600). The per-item aggregated error rate among all 42 data items was 0.3%: 0.1% for quality indicators, 1.3% for demographic/status variables, and 1.7% for administrative items. The per-patient error rate among all 42 data items was 6.3%: 3.0% for quality indicators, 1.7% for demographic/status variables, and 3.0% for administrative items. Trends such as better accuracy for more serious events continue, but observed error rates were lower than those found in previous surveys-an indication that, while further study is needed, nonpunitive voluntary reporting may reduce errors in anesthesia care. PMID:22326979

  5. X-Ray Spectroscopic Observations with ASCA and BeppoSAX

    NASA Astrophysics Data System (ADS)

    Kaastra, J. S.

    Introduction X-ray spectroscopy The ASCA and BeppoSAX missions The most prominent spectral features observable with ASCA and - BeppoSAX A Few Notes on Spectral Data Fitting Introduction Data binning Model binning Calibration uncertainties Spectral deconvolution Statistics Low count rates Data presentation Plasma models Stellar Coronae Introduction Differential emission measure distribution techniques Temperature structure Abundances Flares Stellar evolution Hot Stars Introduction Normal O and B stars Luminous blue variables Wolf-Rayet stars Protostars and T Tauri Stars Introduction X-ray emission from protostars X-ray emission from T Tauri stars Cataclysmic Variables Introduction Non-magnetic cataclysmic variables Intermediate polars Polars High-Mass X-Ray Binaries Introduction Vela X-1 Cyg X-3 Cen X-3 SS 433 Other cases Low-Mass X-Ray Binaries Introduction 4U 1626-67 Cir X-1 Supernova Remnants Introduction Oxygen-ricg remnats: Cas A Young type Ia remnants Old shell-like remnants Synchrotron X-ray emission from SNRs Crab-like remnants Center-filled thermal remnants Jets interacting with SNRs Isolated pulsars The Magellanic Cloud SNRs Supernova explosions in distant galaxies Extended X-Ray Emission from Normal Galaxies The galactic ridge The galactic center X-ray emission from other normal galaxies Seyfert 1 Galaxies The iron line Warm absorbers The power law component Soft components Low-luminosity AGN Broad-line radio galaxies Seyfert 2 Galaxies Introduction NGC 1068 NGC 6552 NGC 4945 NGC 1808 Other cases Intermediate cases: narrow-line emission galaxies and others Quasars Radio-quiet quasars Radio-loud quasars Type 2 quasars BL Lac objects Clusters of Galaxies Temperature distribtuion of the hot medium The cooling flow and the central temperature distribtuion Mass distribution Groups of galaxies Cluster mergers and dynamical evolution Optical-depth effects The quest for the Hubble constant Abundances in nearby clusters Abundances in distant clusters Abundances

  6. Spectroscopic properties of explosive volcanism within the Caloris basin with MESSENGER observations

    NASA Astrophysics Data System (ADS)

    Besse, S.; Doressoundiram, A.; Benkhoff, J.

    2015-12-01

    Volcanism on Mercury has been indisputably identified at various locations on the surface, by means of both effusive and explosive volcanism. Its characterization is crucial to understand the evolution of the planet, in particular the thermal evolution of the mantle, and the volatile content of the planet. This analysis presents a detailed view of the pyroclastic deposits of the Caloris basin. Observations from the Mercury Atmospheric and Surface Composition Spectrometer (MASCS) are used to understand the spectral characteristics of the pyroclastic deposits, both in the visible and near-infrared. Additional calibration steps are proposed to reconcile the difference of absolute reflectance between the visible (VIS) and near-infrared (NIR) detectors. These calibration steps allow the use of the full spectral range of the MASCS instrument. Pyroclastic deposits exhibit a redder spectral slope in the VIS and NIR. This spectral slope diminishes toward the edge of the deposits to match that of Mercury's average surface. Spectral properties in the ultraviolet (UV) also change as a function of distance to the vent. Only the UV properties unambiguously separate the pyroclastic deposits from Mercury's average spectra. The spectral variations are consistent with a lower iron content of the pyroclastic deposits with respect to the average surface of Mercury, similar to what has been proposed for pyrolcastic deposits on the lunar surface. Nonetheless, given the limited illumination conditions diversity of the MASCS instrument, other causes such as grain size, space weathering, and bulk composition could also be accounted for the spectral variations. Variability of the pyroclastic deposits' properties within the entire basin are potentially identified between the three main clusters, and could be related to space weathering of deposits of different ages.

  7. Herschel spectroscopic observations of the compact obscured nucleus in Zw 049.057

    NASA Astrophysics Data System (ADS)

    Falstad, N.; González-Alfonso, E.; Aalto, S.; van der Werf, P. P.; Fischer, J.; Veilleux, S.; Meléndez, M.; Farrah, D.; Smith, H. A.

    2015-08-01

    Context. The luminous infrared galaxy Zw 049.057 contains a compact obscured nucleus where a considerable amount of the galaxy's luminosity is generated. This nucleus contains a dusty environment that is rich in molecular gas. One approach to probing this kind of environment and to revealing what is hidden behind the dust is to study the rotational lines of molecules that couple well with the infrared radiation emitted by the dust. Aims: We probe the physical conditions in the core of Zw 049.057 and establish the nature of its nuclear power source (starburst or active galactic nucleus). Methods: We observed Zw 049.057 with the Photodetector Array Camera and Spectrometer (PACS) and the Spectral and Photometric Imaging Receiver (SPIRE) onboard the Herschel Space Observatory in rotational lines of H2O, H218O, OH, 18OH, and [O I]. We modeled the unresolved core of the galaxy using a spherically symmetric radiative transfer code. To account for the different excitation requirements of the various molecular transitions, we use multiple components and different physical conditions. Results: We present the full high-resolution SPIRE FTS spectrum of Zw 049.057, along with relevant spectral scans in the PACS range. We find that a minimum of two different components (nuclear and extended) are required in order to account for the rich molecular line spectrum of Zw 049.057. The nuclear component has a radius of 10-30 pc, a very high infrared surface brightness (~1014L⊙kpc-2), warm dust (Td > 100 K), and a very large H2 column density (NH2 = 1024-1025 cm-2). The modeling also indicates high nuclear H2O (~5 × 10-6) and OH (~4 × 10-6) abundances relative to H2 as well as a low 16O/18O-ratio of 50-100. We also find a prominent infall signature in the [O I] line. We tentatively detect a 500 km s-1 outflow in the H2O 313 → 202 line. Conclusions: The high surface brightness of the core indicates the presence of either a buried active galactic nucleus or a very dense nuclear

  8. Spectroscopic observation of Lyα emitters at z ∼ 7.7 and implications on re-ionization

    SciTech Connect

    Faisst, A. L.; Carollo, C. M.; Capak, P.; Scarlata, C.; Scoville, N.

    2014-06-10

    We present spectroscopic follow-up observations on two bright Lyα emitter (LAE) candidates originally found by Krug et al. at a redshift of z ∼ 7.7 using the Multi-Object Spectrometer for Infra-Red Exploration at Keck. We rule out any line emission at the >5σ level for both objects, putting on solid ground a previous null result for one of the objects. The limits inferred from the non-detections rule out the previous claim of no or even reversed evolution between 5.7 < z < 7.7 in the Lyα luminosity function (LF) and suggest a drop in the Lyα LF consistent with that seen in Lyman break galaxy (LBG) samples. We model the redshift evolution of the LAE LF using the LBG UV-continuum LF and the observed rest-frame equivalent width distribution. From the comparison of our empirical model with the observed LAE distribution, we estimate lower limits of the neutral hydrogen fraction to be 50%-70% at z ∼ 7.7. Together with this, we find a strong evolution in the Lyα optical depth characterized by (1 + z){sup 2.2} {sup ±} {sup 0.5} beyond z = 6, indicative of a strong evolution of the intergalactic medium. Finally, we extrapolate the LAE LF to z ∼ 9 using our model and show that it is unlikely that large area surveys, like UltraVISTA or Euclid, pick up LAEs at this redshift assuming the current depths and area.

  9. Detection of optical path in spectroscopic space-based observations of greenhouse gases: Application to GOSAT data processing

    NASA Astrophysics Data System (ADS)

    Oshchepkov, Sergey; Bril, Andrey; Maksyutov, Shamil; Yokota, Tatsuya

    2011-07-01

    We present a method to detect optical path modification due to atmospheric light scattering in space-based greenhouse gas spectroscopic sounding. This method, which was applied to the analysis of radiance spectra measured by the Greenhouse Gases Observing Satellite (GOSAT), is based on the path length probability density function (PPDF) and on retrieval of PPDF parameters from radiance spectra in the oxygen A-band of absorption at 0.76 μm. We show that these parameters can be effectively used to characterize the impact of atmospheric light scattering on carbon dioxide retrieval in the atmospheric carbon dioxide (CO2) absorption bands at 1.6 μm and 2.0 μm. The threshold for PPDF parameters is set so that the optical-path modification is negligible, and these settings are recommended as a basic guideline for selecting the clearest atmospheric scenarios. An example of data processing for six global GOSAT repeat cycles in April and July 2009 shows that PPDF-based selection efficiently removes CO2 retrieval biases associated with subvisible cirrus and sandstorm activities.

  10. Polarimetric and spectroscopic optical observations of the ultra-compact X-ray binary 4U 0614+091

    NASA Astrophysics Data System (ADS)

    Baglio, M. C.; Mainetti, D.; D'Avanzo, P.; Campana, S.; Covino, S.; Russell, D. M.; Shahbaz, T.

    2014-12-01

    Aims: We present a polarimetric and spectroscopic study of the persistent ultra-compact X-ray binary 4U 0614+091 aimed at searching for the emission of a relativistic particle jet and at unveiling the orbital period Porb of the system. Methods: We obtained r-band polarimetric observations with the Telescopio Nazionale Galileo (TNG) equipped with the PAOLO polarimeter and with the Nordic Optical Telescope (NOT) equipped with the ALFOSC instrument, covering ~2 h and ~0.5 h observations, respectively. We carried out low resolution spectroscopy of the system using the ESO Very Large Telescope equipped with FORS1 for ~1.5 h (16 spectra covering the range 4300-8000 Å). Results: The polarimetric analysis performed starting from the TNG dataset revealed a polarisation degree in the r-band of 3% ± 1%. From the NOT dataset, due to the lower signal-to-noise ratio, we could obtain only a 3σ upper limit of 3.4%. From the joining of a spectroscopic and photometric analysis, through the study of the equivalent width variations of the CII 7240 Å line and the r-band light curve, we could find a hint of a ~45 min periodicity. Conclusions: A polarisation degree P of ~3% in the r-band is consistent with the emission of a relativistic particle jet, which is supposed to emit intrinsically linearly polarised synchrotron radiation. Since no variations of P with time have been detected, and the accretion disc of the system does not contain ionised hydrogen, scattering by free electrons in the accretion disc has been rejected. The period of ~45 min obtained through the analysis of the system light curve and of the equivalent width variations of the selected spectral line is probably linked to the presence of a hot spot or a superhump in the accretion disc, and lead to an orbital period ≳1 h for the binary system. Based on observations made with the Italian Telescopio Nazionale Galileo (TNG) operated on the island of La Palma by the Fundación Galileo Galilei of the INAF (Istituto

  11. Spectroscopically resolved far-IR observations of the massive star-forming region G5.89-0.39

    NASA Astrophysics Data System (ADS)

    Leurini, S.; Wyrowski, F.; Wiesemeyer, H.; Gusdorf, A.; Güsten, R.; Menten, K. M.; Gerin, M.; Levrier, F.; Hübers, H. W.; Jacobs, K.; Ricken, O.; Richter, H.

    2015-12-01

    Context. The fine-structure line of atomic oxygen at 63 μm ([OI]63μm) is an important diagnostic tool in different fields of astrophysics: it is for example predicted to be the main coolant in several environments of star-forming regions (SFRs). However, our knowledge of this line relies on observations with low spectral resolution, and the real contribution of each component (photon-dominated region, jet) in the complex environment of SFRs to its total flux is poorly understood. Aims: We investigate the contribution of jet and photon-dominated region emission, and of absorption to the [OI]63μm line towards the hot gas around the ultra-compact Hii region G5.89-0.39 and study the far-IR line luminosity of the source in different velocity regimes through spectroscopically resolved spectra of atomic oxygen, [CII], CO, OH, and H2O. Methods: We mapped G5.89-0.39 in [OI]63μm and in CO(16-15) with the GREAT receiver onboard SOFIA. We also observed the central position of the source in the ground-state OH 2Π3/2 J = 5/2 → J = 3/2 triplet and in the excited OH 2Π1/2 J = 3/2 → J = 1/2 triplets with SOFIA. These data were complemented with APEX CO(6-5) and CO(7-6) maps and with Herschel/HIFI maps and single-pointing observations in lines of [CII], H2O, and HF. Results: The [OI] spectra in G5.89-0.39 are severely contaminated by absorptions from the source envelope and from different clouds along the line of sight. Emission is detected only at high velocities, and it is clearly associated with the compact north-south outflows traced by extremely high-velocity emission in low-J CO lines. The mass-loss rate and the energetics of the jet system derived from the [OI]63μm line agree well with previous estimates from CO, thus suggesting that the molecular outflows in G5.89-0.39 are driven by the jet system seen in [OI]. The far-IR line luminosity of G5.89-0.39 is dominated by [OI] at high-velocities; the second coolant in this velocity regime is CO, while [CII], OH and H2O

  12. Spectroscopic observation of Mars

    NASA Technical Reports Server (NTRS)

    Singer, R. B.

    1985-01-01

    A review is given of what is known about the surface of Mars from reflectance spectroscopy, including some new results and providing an overview of the principles involved. While some form of bound water and/or OH has been known on Mars for many years, a new result presented is the identification of structural OH in a dilute or poorly crystalline magnesian clay. The detection of water ice in the residual north polar cap is noted. Also considered is the role that reflectance spectroscopy will play in the future, from earth and as an important part of the NASA Mars Geosciences/Climatology Orbiter mission.

  13. Far Ultraviolet Spectroscopic Explorer Observations of the Seyfert 1.5 Galaxy NGC 5548 in a Low State

    NASA Technical Reports Server (NTRS)

    Brotherton, M. S.; Green, R. F.; Kriss, G. A.; Oegerle, W.; Kaiser, M. E.; Zheng, W.; Hutchings, J. B.; Fisher, Richard R. (Technical Monitor)

    2001-01-01

    We present far-ultraviolet spectra of the Seyfert 1.5 galaxy NGC 5548 obtained in 2000 June with the Far Ultraviolet Spectroscopic Explorer (FUSE). Our data span the observed wavelength range 915-1185 A at a resolution of approximately 20 km s(exp -1). The spectrum shows a weak continuum and emission from O VI (lambda)(lambda)1032, 1038, C III (lambda)977, and He II (lambda)1085. The FUSE data were obtained when the AGN (Active Galactic Nuclei) was in a low state, which has revealed strong, narrow O VI emission lines. We also resolve intrinsic, associated absorption lines of O VI and the Lyman series. Several distinct kinematic components are present, spanning a velocity range of approximately 0 to -1300 km s(exp -1) relative to systemic, with kinematic structure similar to that seen in previous observations of longer wavelength ultraviolet (UV) lines. We explore the relationships between the far-UV (ultraviolet) absorbers and those seen previously in the UV and X-rays. We find that the high-velocity UV absorption component is consistent with being low-ionization, contrary to some previous claims, and is consistent with its non-detection in high-resolution X-ray spectra. The intermediate velocity absorbers, at -300 to -400 km s(exp -1), show H I and O VI column densities consistent with having contributions from both a high-ionization X-ray absorber and a low-ionization UV absorber. No single far-UV absorbing component can be solely identified with the X-ray absorber.

  14. Long-term dynamics of multisite phosphorylation.

    PubMed

    Rubinstein, Boris Y; Mattingly, Henry H; Berezhkovskii, Alexander M; Shvartsman, Stanislav Y

    2016-07-15

    Multisite phosphorylation cycles are ubiquitous in cell regulation systems and are studied at multiple levels of complexity, from molecules to organisms, with the ultimate goal of establishing predictive understanding of the effects of genetic and pharmacological perturbations of protein phosphorylation in vivo. Achieving this goal is essentially impossible without mathematical models, which provide a systematic framework for exploring dynamic interactions of multiple network components. Most of the models studied to date do not discriminate between the distinct partially phosphorylated forms and focus on two limiting reaction regimes, distributive and processive, which differ in the number of enzyme-substrate binding events needed for complete phosphorylation or dephosphorylation. Here we use a minimal model of extracellular signal-related kinase regulation to explore the dynamics of a reaction network that includes all essential phosphorylation forms and arbitrary levels of reaction processivity. In addition to bistability, which has been studied extensively in distributive mechanisms, this network can generate periodic oscillations. Both bistability and oscillations can be realized at high levels of reaction processivity. Our work provides a general framework for systematic analysis of dynamics in multisite phosphorylation systems. PMID:27226482

  15. Optical Spectroscopic Observations of Gamma-ray Blazar Candidates. V. TNG, KPNO, and OAN Observations of Blazar Candidates of Uncertain Type in the Northern Hemisphere

    NASA Astrophysics Data System (ADS)

    Álvarez Crespo, N.; Masetti, N.; Ricci, F.; Landoni, M.; Patiño-Álvarez, V.; Massaro, F.; D'Abrusco, R.; Paggi, A.; Chavushyan, V.; Jiménez-Bailón, E.; Torrealba, J.; Latronico, L.; La Franca, F.; Smith, Howard A.; Tosti, G.

    2016-02-01

    The extragalactic γ-ray sky is dominated by emission from blazars, a peculiar class of active galactic nuclei. Many of the γ-ray sources included in the Fermi-Large Area Telescope Third Source catalog (3FGL) are classified as blazar candidates of uncertain type (BCUs) because there are no optical spectra available in the literature to confirm their nature. In 2013, we started a spectroscopic campaign to look for the optical counterparts of the BCUs and of the unidentified γ-ray sources to confirm their blazar nature. Whenever possible we also determine their redshifts. Here, we present the results of the observations carried out in the northern hemisphere in 2013 and 2014 at the Telescopio Nazionale Galileo, Kitt Peak National Observatory, and Observatorio Astronómico Nacional in San Pedro Mártir. In this paper, we describe the optical spectra of 25 sources. We confirmed that all of the 15 BCUs observed in our campaign and included in our sample are blazars and we estimated the redshifts for three of them. In addition, we present the spectra for three sources classified as BL Lacs in the literature but with no optical spectra available to date. We found that one of them is a quasar (QSO) at a redshift of z = 0.208 and the other two are BL Lacs. Moreover, we also present seven new spectra for known blazars listed in the Roma-BZCAT that have an uncertain redshift or are classified as BL Lac candidates. We found that one of them, 5BZB J0724+2621, is a “changing look” blazar. According to the spectrum available in the literature, it was classified as a BL Lac, but in our observation we clearly detected a broad emission line that led us to classify this source as a QSO at z = 1.17.

  16. Spectroscopic observations of propagating disturbances in a polar coronal hole: evidence of slow magneto-acoustic waves

    NASA Astrophysics Data System (ADS)

    Gupta, G. R.; Teriaca, L.; Marsch, E.; Solanki, S. K.; Banerjee, D.

    2012-10-01

    Aims: We focus on detecting and studying quasi-periodic propagating features that have been interpreted in terms of both slow magneto-acoustic waves and of high-speed upflows. Methods: We analyzed long-duration spectroscopic observations of the on-disk part of the south polar coronal hole taken on 1997 February 25 by the SUMER spectrometer onboard SOHO. We calibrated the velocity with respect to the off-limb region and obtained time-distance maps in intensity, Doppler velocity, and line width. We also performed a cross-correlation analysis on different time series curves at different latitudes. We studied average spectral line profiles at the roots of propagating disturbances and along the propagating ridges, and performed a red-blue asymmetry analysis. Results: We clearly find propagating disturbances in intensity and Doppler velocity with a projected propagation speed of about 60 ± 4.8 km s-1 and a periodicity of ≈14.5 min. To our knowledge, this is the first simultaneous detection of propagating disturbances in intensity as well as in Doppler velocity in a coronal hole. During the propagation, an intensity enhancement is associated with a blueshifted Doppler velocity. These disturbances are clearly seen in intensity also at higher latitudes (i.e., closer to the limb), while disturbances in Doppler velocity become faint there. The spectral line profiles averaged along the propagating ridges are found to be symmetric, to be well fitted by a single Gaussian, and have no noticeable red-blue asymmetry. Conclusions: Based on our analysis, we interpret these disturbances in terms of propagating slow magneto-acoustic waves.

  17. Latent Variable Regression 4-Level Hierarchical Model Using Multisite Multiple-Cohorts Longitudinal Data. CRESST Report 801

    ERIC Educational Resources Information Center

    Choi, Kilchan

    2011-01-01

    This report explores a new latent variable regression 4-level hierarchical model for monitoring school performance over time using multisite multiple-cohorts longitudinal data. This kind of data set has a 4-level hierarchical structure: time-series observation nested within students who are nested within different cohorts of students. These…

  18. OBSERVING THE FINE STRUCTURE OF LOOPS THROUGH HIGH-RESOLUTION SPECTROSCOPIC OBSERVATIONS OF CORONAL RAIN WITH THE CRISP INSTRUMENT AT THE SWEDISH SOLAR TELESCOPE

    SciTech Connect

    Antolin, P.; Rouppe van der Voort, L. E-mail: v.d.v.l.rouppe@astro.uio.no

    2012-02-01

    Observed in cool chromospheric lines, such as H{alpha} or Ca II H, coronal rain corresponds to cool and dense plasma falling from coronal heights. Considered as a peculiar sporadic phenomenon of active regions, it has not received much attention since its discovery more than 40 years ago. Yet, it has been shown recently that a close relationship exists between this phenomenon and the coronal heating mechanism. Indeed, numerical simulations have shown that this phenomenon is most likely due to a loss of thermal equilibrium ensuing from a heating mechanism acting mostly toward the footpoints of loops. We present here one of the first high-resolution spectroscopic observations of coronal rain, performed with the CRisp Imaging Spectro Polarimeter (CRISP) instrument at the Swedish Solar Telescope. This work constitutes the first attempt to assess the importance of coronal rain in the understanding of the coronal magnetic field in active regions. With the present resolution, coronal rain is observed to literally invade the entire field of view. A large statistical set is obtained in which dynamics (total velocities and accelerations), shapes (lengths and widths), trajectories (angles of fall of the blobs), and thermodynamic properties (temperatures) of the condensations are derived. Specifically, we find that coronal rain is composed of small and dense chromospheric cores with average widths and lengths of {approx}310 km and {approx}710 km, respectively, average temperatures below 7000 K, displaying a broad distribution of falling speeds with an average of {approx}70 km s{sup -1}, and accelerations largely below the effective gravity along loops. Through estimates of the ion-neutral coupling in the blobs we show that coronal rain acts as a tracer of the coronal magnetic field, thus supporting the multi-strand loop scenario, and acts as a probe of the local thermodynamic conditions in loops. We further elucidate its potential in coronal heating. We find that the cooling

  19. Follow-up spectroscopic observations of HD 107148 B: A new white dwarf companion of an exoplanet host star

    NASA Astrophysics Data System (ADS)

    Mugrauer, M.; Dinçel, B.

    2016-07-01

    We report on our follow-up spectroscopy of HD 1071478 B, a recently detected faint co-moving companion of the exoplanet host star HD 107148 A. The companion is separated from its primary star by about 35 arcsec (or 1790 AU of projected separation) and its optical and near infrared photometry is consistent with a white dwarf, located at the distance of HD 107148 A. In order to confirm the white dwarf nature of the co-moving companion, we obtained follow-up spectroscopic observations of HD 107148 B with CAFOS at the CAHA 2.2 m telescope. According to our CAFOS spectroscopy HD 107148 B is a DA white dwarf with an effective temperature in the range between 5900 and 6400 K. The properties of HD 107148 B can further be constrained with the derived effective temperature and the known visual and infrared photometry of the companion, using evolutionary models of DA white dwarfs. We obtain for HD 107148 B a mass of 0.56±0.05 M_ȯ, a luminosity of (2.0±0.2)×10-4 L_ȯ, log g [cm s-2])=7.95±0.09, and a cooling age of 2100±270 Myr. With its white dwarf companion the exoplanet host star HD 107148 A forms an evolved stellar system, which hosts at least one exoplanet. So far, only few of these evolved systems are known, which represent only about 5 % of all known exoplanet host multiple stellar systems. HD 107148 B is the second confirmed white dwarf companion of an exoplanet host star with a projected separation to its primary star of more than 1000 AU. Based on observations collected at the Centro Astronómico Hispano Alemán (CAHA) at Calar Alto, operated jointly by the Max-Planck Institut für Astronomie and the Instituto de Astrofísica de Andalucía (CSIC).

  20. Spectroscopic mode identification of main-sequence non-radially pulsating stars

    NASA Astrophysics Data System (ADS)

    Maisonneuve, F.; Pollard, K. R.; Cottrell, P. L.; Kilmartin, P. M.; Wright, D. J.; De Cat, P.

    2010-07-01

    We are undertaking an extensive observational campaign of a number of non-radially pulsating stars using the high-resolution HERCULES spectrograph on the 1.0-m telescope at the Mt John University Observatory. This is part of a large world-wide multi-site campaign to improve mode-identification techniques in non-radially pulsating stars, particularly for g-mode pulsators. This paper outlines our campaign and presents preliminary results for one γ Doradus star, HD 40745, and one β Cephei star, HD 61068. We have used a representative cross-correlation line-profile technique presented by Wright in 2008 to extract line profiles and these have then been analyzed using the FAMIAS package due to Zima published in 2006 to derive a spectroscopic mode identification.

  1. Nonlinear instabilities of multi-site breathers in Klein-Gordon lattices

    DOE PAGESBeta

    Cuevas-Maraver, Jesus; Kevrekidis, Panayotis G.; Pelinovsky, Dmitry E.

    2015-12-14

    Here, we explore the possibility of multi-site breather states in a nonlinear Klein–Gordon lattice to become nonlinearly unstable, even if they are found to be spectrally stable. The mechanism for this nonlinear instability is through the resonance with the wave continuum of a multiple of an internal mode eigenfrequency in the linearization of excited breather states. For the nonlinear instability, the internal mode must have its Krein signature opposite to that of the wave continuum. This mechanism is not only theoretically proposed, but also numerically corroborated through two concrete examples of the Klein–Gordon lattice with a soft (Morse) and amore » hard (Φ4) potential. Compared to the case of the nonlinear Schrödinger lattice, the Krein signature of the internal mode relative to that of the wave continuum may change depending on the period of the multi-site breather state. For the periods for which the Krein signatures of the internal mode and the wave continuum coincide, multi-site breather states are observed to be nonlinearly stable.« less

  2. Nonlinear instabilities of multi-site breathers in Klein-Gordon lattices

    SciTech Connect

    Cuevas-Maraver, Jesus; Kevrekidis, Panayotis G.; Pelinovsky, Dmitry E.

    2015-12-14

    Here, we explore the possibility of multi-site breather states in a nonlinear Klein–Gordon lattice to become nonlinearly unstable, even if they are found to be spectrally stable. The mechanism for this nonlinear instability is through the resonance with the wave continuum of a multiple of an internal mode eigenfrequency in the linearization of excited breather states. For the nonlinear instability, the internal mode must have its Krein signature opposite to that of the wave continuum. This mechanism is not only theoretically proposed, but also numerically corroborated through two concrete examples of the Klein–Gordon lattice with a soft (Morse) and a hard (Φ4) potential. Compared to the case of the nonlinear Schrödinger lattice, the Krein signature of the internal mode relative to that of the wave continuum may change depending on the period of the multi-site breather state. For the periods for which the Krein signatures of the internal mode and the wave continuum coincide, multi-site breather states are observed to be nonlinearly stable.

  3. Stellar and circumstellar activity in the Be star EW Lacertae from the 1993 multi-site campaign

    NASA Astrophysics Data System (ADS)

    Floquet, M.; Hubert, A. M.; Hirata, R.; McDavid, D.; Zorec, J.; Gies, D.; Hahula, M.; Janot-Pacheco, E.; Kambe, E.; Leister, N. V.; Štefl, S.; Tarasov, A.; Neiner, C.

    2000-10-01

    A multi-site, multi-technique campaign on the Be star EW Lac was held for about 9 days in August-September 1993. We present results of the analysis of visual, high S/N spectroscopic data (He I 6678 Å and Hα ). Search for short-term variability was carried out on He I 6678 (line profiles, radial velocity (RV), equivalent width (EW), full width at half-maximum (FWHM) on the absorption part of the line profile and on violet (V) and red (R) emission peaks) and on Hα emission line (line profiles, EW, V, R and V/R ratio). The presence of multi-periodicity is confirmed and we detected the frequencies found in 1989 by Floquet et al. (1992) during a 8-day mono-site campaign. Possible non-radial pulsation solutions for the main frequencies detected are l ~ 2-3, | m | ~ 2-3. We found evidence on the He I 6678 line of episodic matter outflows through the presence of relatively broad, variable absorption line-profile variations. At least one sharp absorption feature was also observed slowly crossing the stellar disc. It is attributed to a blob of matter temporarily orbiting the star. A brief account is given of broad-band polarimetric observations, performed over 6 nights. A correlation is found between the variation in intrinsic polarization level in the B-band and He I 6678 Å strength. Finally, we present a simple model that reproduces rather well the additional ``pseudo-photosphere" contribution in 1993 as opposed to 1989.

  4. Variations in the D/H Ratio of Extended Sight Lines from Far Ultraviolet Spectroscopic Explorer Observations

    NASA Astrophysics Data System (ADS)

    Oliveira, Cristina M.; Hébrard, Guillaume

    2006-12-01

    We use new FUSE data to determine the column densities of interstellar D I, N I, O I, Fe II, and H2 along the HD 41161 and HD 53975 sight lines. Together with N(H I) from the literature, we derive D/H, N/H, and O/H ratios. These sight lines have logN(H I)>21.00 and probe gas up to ~1300 pc, allowing us to determine the gas-phase D/H ratio in a hydrogen column density range, logN(H)>20.70, where the only five measurements available in the literature yield a weighted average of D/H=(0.86+/-0.08)×10-5. We find D/H=(2.14+0.51-0.43)×10-5 along the HD 41161 sight line. This ratio is ~3 σ higher than the weighted mean D/H ratio quoted above, while the D/H ratio for the HD 53975 line of sight, D/H=(1.02+0.23-0.20)×10-5, agrees within the 1 σ uncertainties. Our D/H measurement along the HD 41161 sight line presents the first evidence of variations of D/H at high N(H). Our result seems to indicate either that the long sight lines that, according to the deuterium depletion model, are dominated by cold undisturbed gas where deuterium would be depleted onto carbonaceous grains occur at higher N(H) than previously thought, or that the clumping of low D/H values in the literature for the long sight lines has another explanation. Both of the O/H ratios derived here, (9.12+2.15-1.83)×10-4 and (5.37+1.35-1.14)×10-4 (for HD 41161 and HD 53975, respectively), are higher than what has been found by other authors. Finally, we derive (N/H)×105=8.32+2.09-1.76 and 5.07+1.45-1.21, and (D/O)×102=2.29+0.40-0.35 and 1.91+0.51-0.43, for HD 41161 and HD 53975, respectively. In addition, the relatively high signal-to-noise ratio of the HD 41161 data allows us to place constraints on the f-values of some neutral chlorine transitions present in the FUSE bandpass for which only theoretical values are available. Based on observations made with the NASA-CNES-CSA Far Ultraviolet Spectroscopic Explorer. FUSE is operated for NASA by the Johns Hopkins University under NASA contract NAS5-32985.

  5. Spectroscopic analyses of subluminous B stars: observational constraints for the theory of stellar evolution, pulsation, and diffusion

    NASA Astrophysics Data System (ADS)

    Edelmann, Heinz

    2003-06-01

    This thesis deals with quantitative spectroscopic analyses of large samples of subluminous B stars in order to find constraints the theory of stellar evolution, pulsation, and diffusion. Subluminous B stars, also known as subdwarf B (sdB) stars, are very important in several respects: They dominate the population of faint blue stars in high galactic latitudes, and are found both in the field and in globular clusters. Therefore, sdB stars are important to understand the structure and evolution of our galaxy. From the cosmological point of view, they are candidate progenitors of supernovae of type Ia due to their membership in close binary systems. In the context of stellar astrophysics, subdwarf B stars play an important role because several of them are discovered to show non-radial pulsations, which allows to probe their interior by asteroseismology. Last but not least, sdB stars show very peculiar element abundance patterns, probably caused by diffusion processes. Subluminous B stars are generally considered to be core helium-burning stars with extremely thin hydrogen envelopes (< 0.02M) and masses around 0.5M. In the Hertzsprung-Russell diagram they populate a very narrow area which lies on a blue-ward extension of the horizontal branch (HB), the so called "Extreme Horizontal Branch" (EHB). Due to their thin hydrogen-rich envelope, they cannot sustain a hydrogen-burning shell. This means that the sdB stars cannot ascend the asymptotic giant branch after the end of the helium-core burning, but should evolve directly to the white dwarf graveyard. However, according to standard stellar evolution theory, subdwarf B stars should not exist. Their evolution is still unclear and several scenarios are under debate. For all these investigations, knowledge of the stellar parameters (effective temperature, gravity and chemical composition) is very important to verify or discard theoretical models and predictions. Numerous observing runs have been performed mostly by myself

  6. Multisite adsorption of cadmium on goethite

    SciTech Connect

    Venema, P.; Hiemstra, T.; Riemsdijk, W.H. van

    1996-11-10

    Recently a new general ion adsorption model has been developed for ion binding to mineral surfaces (Hiemstra and van Riemsdijk, 1996). The model uses the Pauling concept of charge distribution (CD) and is an extension of the multi-site complexation (MUSIC) approach. In the CD-MUSIC model the charge of an adsorbing ion that forms an inner sphere complex is distributed over its ligands, which are present in two different electrostatic planes. In this paper the authors have applied the CD-MUSIC model to the adsorption of metal cations, using an extended data set for cadmium adsorbing on goethite. The adsorption of cadmium and the cadmium-proton exchange ratio were measured as function of metal ion concentration, pH, and ionic strength. The data could be described well, taking into account the surface heterogeneity resulting from the presence of two different crystal planes (the dominant 110 face and the minor 021 face). The surface species used in the model are consistent with recent EXAFS data. In accordance with the EXAFS results, high-affinity complexes at the 021 face were used in the model.

  7. Encoded multisite two-photon microscopy

    PubMed Central

    Ducros, Mathieu; Houssen, Yannick Goulam; Bradley, Jonathan; de Sars, Vincent; Charpak, Serge

    2013-01-01

    The advent of scanning two-photon microscopy (2PM) has created a fertile new avenue for noninvasive investigation of brain activity in depth. One principal weakness of this method, however, lies with the limit of scanning speed, which makes optical interrogation of action potential-like activity in a neuronal network problematic. Encoded multisite two-photon microscopy (eMS2PM), a scanless method that allows simultaneous imaging of multiple targets in depth with high temporal resolution, addresses this drawback. eMS2PM uses a liquid crystal spatial light modulator to split a high-power femto-laser beam into multiple subbeams. To distinguish them, a digital micromirror device encodes each subbeam with a specific binary amplitude modulation sequence. Fluorescence signals from all independently targeted sites are then collected simultaneously onto a single photodetector and site-specifically decoded. We demonstrate that eMS2PM can be used to image spike-like voltage transients in cultured cells and fluorescence transients (calcium signals in neurons and red blood cells in capillaries from the cortex) in depth in vivo. These results establish eMS2PM as a unique method for simultaneous acquisition of neuronal network activity. PMID:23798397

  8. Multi-site continuous spectroscopy. 2: Spectrophotometry and energy budget of exceptional white-light flares on HR 1099 from the MUSICOS 89 campaign

    NASA Astrophysics Data System (ADS)

    Foing, B. H.; Char, S.; Ayres, T.; Catala, C.; Neff, J. E.; Zhai, D. S.; Catalano, S.; Cutispoto, G.; Jankov, S.; Rodono, M.; Simon, T.; Akan, C.; Aslanov, A.; Avellar, P.; Baudrand, J.; Beust, H.; Cao, H.; Chatzichristou, H.; Cuby, J. G.; Czarny, J.; de La Reza, R.; Dreux, M.; Felenbok, P.; Ferlet, R.; Frasca, A.; Floquet, M.; Ghosh, K.; Guo, Z.; Guerin, J.; Hao, J. X.; Houdebine, E. R.; Huang, L.; Hubert, A. M.; Hubert, H.; Huovelin, J.; Hron, J.; Ibanoglu, C.; Jiang, S.; Keskin, V.; Lagrange-Henri, A. M.; Lecontel, J. M.; Li, Q.; Mavridis, L.; Nolthenius, R.; Petrov, P.; Savanov, I.; Scherbakov, A.; Tuominen, I.; Vidal-Madjar, A.; Zhang, R.; Zhang, X.

    1994-12-01

    We report results from the December 89 multi-site continuous observing campaign (MUSICOS (MUlti-SIte COntinuous Spectroscopic) 89) dedicated to the study of surface active structures and flares on the RS CVn-type system HR 1099 (= V711 Tau). This system has been observed by up to 17 telescopes around the globe during this campaign. We obtained complete phase coverage for Doppler imaging of photospheric spots. Quasi-simultaneously, we observed the modulation of Ca II K line profile due to chromospheric plage regions. At least two exceptional white-light flares on 14 Dec. 15:00 UT and 15 Dec. 1:00 UT (the largest such optical flare episode ever reported in a RS CVn system) were detected photometrically with typical rise and decay times of 60-90 min, and with remarkable spectral dynamic signatures in H-alpha with longer decay time scale. Equivalent colors, temperature excesses and projected flare areas (0.55 and 0.89 solar disc areas) were derived for the two optical flares. We estimate the energy budget for these two events, with respective peak intensities of radiative losses of 1.65 and 14 x 1033 erg/s and integrated losses over the white-light event duration of a few hours of 8 x 1036 and 1038 ergs (in the 3100-5900 A range), indicating a total energy balance several times these values. The emission was also measured in the H-alpha and H-Beta lines during these flares with a ratio of flare optical emission over Balmer emission 3-4 times larger compared to other flares on dwarfs. More than one day after the last white-light flare, part of the flare decay phase was also measured with IUE in UV lines of low and high excitation; the extrapolated transition region EUV losses are found similar to the derived Balmer line losses. Both flares were shown to occur near the limb. We derive their physical area, and estimate their densities, column mass, and penetration depth. From Balmer line broadening and flows, we derive a kinetic energy budget comparable to the radiative

  9. NEW RESULTS FROM THE MAGELLAN IMACS SPECTROSCOPIC Ly{alpha} SURVEY: NICMOS OBSERVATIONS OF Ly{alpha} EMITTERS AT z = 5.7

    SciTech Connect

    Henry, Alaina L.; Martin, Crystal L.; Dressler, Alan; McCarthy, Patrick; Sawicki, Marcin

    2010-08-10

    We present NICMOS J {sub 110} (rest-frame 1200-2100 A) observations of the three z = 5.7 Ly{alpha} emitters discovered in the blind multislit spectroscopic survey by Martin et al. These images confirm the presence of the two sources that were previously only seen in spectroscopic observations. The third source, which is undetected in our J {sub 110} observations, has been detected in narrowband imaging of the Cosmic Origins Survey, so our non-detection implies a rest-frame equivalent width >146 A (3{sigma}). The two J {sub 110}-detected sources have more modest rest-frame equivalent widths of 30-40 A, but all three are typical of high-redshift Ly{alpha} emitters. In addition, the J {sub 110}-detected sources have UV luminosities that are within a factor of 2 of L*{sub UV}, and sizes that appear compact (r {sub hl{approx}} 0.''15) in our NIC2 images-consistent with a redshift of 5.7. We use these UV-continuum and Ly{alpha} measurements to estimate the i {sub 775}-z {sub 850} colors of these galaxies and show that at least one and possibly all three would be missed by the i-dropout Lyman break galaxy selection. These observations help demonstrate the utility of multislit narrowband spectroscopy as a technique for finding faint emission-line galaxies.

  10. Spectroscopic Investigation of the Carotenoid Deoxyperidinin: Direct Observation of the Forbidden S0 → S1 Transition.

    PubMed

    Greco, Jordan A; LaFountain, Amy M; Kinashi, Naoto; Shinada, Tetsuro; Sakaguchi, Kazuhiko; Katsumura, Shigeo; Magdaong, Nikki Cecil M; Niedzwiedzki, Dariusz M; Birge, Robert R; Frank, Harry A

    2016-03-17

    This paper presents a spectroscopic investigation of deoxyperidinin, a synthetic peridinin analogue in which the carbonyl functional group in peridinin was replaced by a nonconjugated methylene group. Steady-state and ultrafast time-resolved absorption and fluorescence spectroscopic experiments are carried out on deoxyperidinin in n-hexane and acetonitrile at room temperature and in 2-methyltetrahydrofuran at 77 K. The spectra of deoxyperidinin have higher vibronic resolution compared to those of peridinin. The higher resolution is due to a substantial reduction in both molecular conformational disorder and inhomogeneous broadening of the spectra of deoxyperidinin compared to peridinin. Features in the steady-state absorption spectrum of deoxyperidinin that are not evident in the spectrum of peridinin are unambiguously assigned to the forbidden S0 (1(1)Ag(-)) → S1 (2(1)Ag(-)) absorption transition. The characteristics of both the steady-state and time-resolved spectra are interpreted using EOM-CCSD, SAC-CI, and MNDO-PSDCI quantum computational formalisms that provided a theoretical framework for understanding the photophysical properties of the molecules. PMID:26907520

  11. Independent iPTF detection and spectroscopic follow-up observations of the Type II SN 2013am = iPTF13aaz in M65

    NASA Astrophysics Data System (ADS)

    Yaron, O.; Gal-Yam, A.; Fox, O. D.; Kelly, P.; Zheng, W.; Cenko, S. B.; Filippenko, A. V.; Silverman, J. M.; Walker, E. S.; Mazzali, P. A.; Pian, E.; Nugent, P. E.; Cao, Y.; Horesh, A.; Kasliwal, M. M.

    2013-03-01

    The iPTF (ATel #4807) announces its independent detection, spectroscopic classification, and follow-up observations of the Type II SN in the nearby galaxy M65 (d = 12.6 Mpc; NED), at RA = 11:18:56.9, Dec = +13:03:50.0 (J2000). The object was discovered on 2013-03-21.637 by M. Sugano, Kakogawa, Hyogo-ken, Japan and posted on the CBAT TOCP page, http://www.cbat.eps.harvard.edu/unconf/followups/J11185695+1303494.html , where it was designated PSN J11185695+1303494 and later renamed SN 2013am (CBET #3440).

  12. The Wasilewski sample of emission-line galaxies - Follow-up CCD imaging and spectroscopic and IRAS observations

    NASA Technical Reports Server (NTRS)

    Bothun, Gregory D.; Schmitz, Mark; Halpern, Jules P.; Lonsdale, Carol J.; Impey, Chris

    1989-01-01

    The results of an extensive imaging and spectroscopic follow-up of the objective prism-selected emission line galaxy (ELG) sample of Wasilewski (1982) are presented. Fluxes at 12, 25, 60, and 100 microns were also obtained from the coadded IRAS survey data. ELGs found by objective prism surveys are found to be generally small and underluminous galaxies which usually have higher than average optical surface brightness. The Seyfert detection rate in objective prism surveys is roughly 10 percent and the ratio of the space densities of Seyfert 2 to Seyfert 1 galaxies is significantly larger than unity. Most of the galaxies selected by objective prism surveys are star-forming, late-type spirals which often show disturbed morphology. About 25 percent of the galaxies detected by the surveys are faint, high-excitation metal-poor compact H II regions.

  13. Development of a high dynamic range spectroscopic system for observation of neutral hydrogen atom density distribution in Large Helical Device core plasma

    SciTech Connect

    Fujii, K. Atsumi, S.; Watanabe, S.; Shikama, T.; Hasuo, M.; Goto, M.; Morita, S.

    2014-02-15

    We report development of a high dynamic range spectroscopic system comprising a spectrometer with 30% throughput and a camera with a low-noise fast-readout complementary metal-oxide semiconductor sensor. The system achieves a 10{sup 6} dynamic range (∼20 bit resolution) and an instrumental function approximated by a Voigt profile with Gauss and Lorentz widths of 31 and 0.31 pm, respectively, for 656 nm light. The application of the system for line profile observations of the Balmer-α emissions from high temperature plasmas generated in the Large Helical Device is also presented. In the observed line profiles, emissions are detected in far wings more than 1.0 nm away from the line center, equivalent to neutral hydrogen atom kinetic energies above 1 keV. We evaluate atom density distributions in the core plasma by analyzing the line profiles.

  14. Optical spectroscopic observations of blazars and γ-ray blazar candidates in the Sloan digital sky survey data release nine

    SciTech Connect

    Massaro, F.; Masetti, N.; D'Abrusco, R.; Paggi, A.; Funk, S.

    2014-10-01

    We present an analysis of the optical spectra available in the Sloan Digital Sky Survey data release nine (SDSS DR9) for the blazars listed in the ROMA-BZCAT and for the γ-ray blazar candidates selected according to their IR colors. First, we adopt a statistical approach based on Monte Carlo simulations to find the optical counterparts of the blazars listed in the ROMA-BZCAT catalog. Then, we crossmatched the SDSS spectroscopic catalog with our selected samples of blazars and γ-ray blazar candidates, searching for those with optical spectra available to classify our blazar-like sources and, whenever possible, to confirm their redshifts. Our main objectives are to determine the classification of uncertain blazars listed in the ROMA-BZCAT and to discover new gamma-ray blazars. For the ROMA-BZCAT sources, we investigated a sample of 84 blazars, confirming the classification for 20 of them and obtaining 18 new redshift estimates. For the γ-ray blazars, indicated as potential counterparts of unassociated Fermi sources or with uncertain nature, we established the blazar-like nature of 8 out of the 27 sources analyzed and confirmed 14 classifications.

  15. Spectroscopic survey of Kepler stars. I. HERMES/Mercator observations of A- and F-type stars

    NASA Astrophysics Data System (ADS)

    Niemczura, E.; Murphy, S. J.; Smalley, B.; Uytterhoeven, K.; Pigulski, A.; Lehmann, H.; Bowman, D. M.; Catanzaro, G.; van Aarle, E.; Bloemen, S.; Briquet, M.; De Cat, P.; Drobek, D.; Eyer, L.; Gameiro, J. F. S.; Gorlova, N.; Kamiński, K.; Lampens, P.; Marcos-Arenal, P.; Pápics, P. I.; Vandenbussche, B.; Van Winckel, H.; Stȩślicki, M.; Fagas, M.

    2015-07-01

    The Kepler space mission provided near-continuous and high-precision photometry of about 207 000 stars, which can be used for asteroseismology. However, for successful seismic modeling it is equally important to have accurate stellar physical parameters. Therefore, supplementary ground-based data are needed. We report the results of the analysis of high-resolution spectroscopic data of A- and F-type stars from the Kepler field, which were obtained with the HERMES spectrograph on the Mercator telescope. We determined spectral types, atmospheric parameters and chemical abundances for a sample of 117 stars. Hydrogen Balmer, Fe I, and Fe II lines were used to derive effective temperatures, surface gravities, and microturbulent velocities. We determined chemical abundances and projected rotational velocities using a spectrum synthesis technique. The atmospheric parameters obtained were compared with those from the Kepler Input Catalogue (KIC), confirming that the KIC effective temperatures are underestimated for A stars. Effective temperatures calculated by spectral energy distribution fitting are in good agreement with those determined from the spectral line analysis. The analysed sample comprises stars with approximately solar chemical abundances, as well as chemically peculiar stars of the Am, Ap, and λ Boo types. The distribution of the projected rotational velocity, vsin i, is typical for A and F stars and ranges from 8 to about 280 km s-1, with a mean of 134 km s-1.

  16. From gateway to multisite gateway in one recombination event

    Technology Transfer Automated Retrieval System (TEKTRAN)

    We created a construct, pDONR-R4-R3, to easily convert any available Gateway destination vector to a MultiSite Gateway vector in a single recombination reaction. In addition, we designed pDONR-R4-R3 so that DNA fragments already cloned upstream or downstream of the Gateway cassette in the original d...

  17. A Multisite Evaluation of Reading Is Fundamental: Summary Report.

    ERIC Educational Resources Information Center

    Parker, Ronald K.; And Others

    Reading Is Fundamental (RIF) is a national program that seeks to motivate children to read. Implemented by local sponsors and aimed at disadvantaged groups, it offers participating children a wide selection of attractive paperback books about interesting people, places, and events. The multisite evaluation summarized in this report studied…

  18. A Multisite Evaluation of Reading Is Fundamental: Technical Report.

    ERIC Educational Resources Information Center

    Parker, Ronald K.; And Others

    Reading Is Fundamental (RIF) is a national program that seeks to motivate children to read. Implemented by local sponsors and aimed at disadvantaged groups, it offers participating children a wide selection of attractive paperbound books about interesting people, places, and events. The multisite evaluation discussed in this technical report…

  19. Multi-Sited Ethnography and the Field of Educational Research

    ERIC Educational Resources Information Center

    Pierides, Dean

    2010-01-01

    This paper responds to the challenge of how educational research might be practised in a contemporary world that is no longer necessarily organised by nearness and unity. Focusing on ethnography, it argues for what a multi-sited imaginary contributes to research in the field of education. By giving prominence to the notion of multi-sited…

  20. A Multisite Cluster Randomized Field Trial of Open Court Reading

    ERIC Educational Resources Information Center

    Borman, Geoffrey D.; Dowling, N. Maritza; Schneck, Carrie

    2008-01-01

    In this article, the authors report achievement outcomes of a multisite cluster randomized field trial of Open Court Reading 2005 (OCR), a K-6 literacy curriculum published by SRA/McGraw-Hill. The participants are 49 first-grade through fifth-grade classrooms from predominantly minority and poor contexts across the nation. Blocking by grade level…

  1. Hydrological modeling using a multi-site stochastic weather generator

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Weather data is usually required at several locations over a large watershed, especially when using distributed models for hydrological simulations. In many applications, spatially correlated weather data can be provided by a multi-site stochastic weather generator which considers the spatial correl...

  2. Replication and Comparison of the Newly Proposed ADOS-2, Module 4 Algorithm in ASD without ID: A Multi-Site Study

    ERIC Educational Resources Information Center

    Pugliese, Cara E.; Kenworthy, Lauren; Bal, Vanessa Hus; Wallace, Gregory L.; Yerys, Benjamin E.; Maddox, Brenna B.; White, Susan W.; Popal, Haroon; Armour, Anna Chelsea; Miller, Judith; Herrington, John D.; Schultz, Robert T.; Martin, Alex; Anthony, Laura Gutermuth

    2015-01-01

    Recent updates have been proposed to the Autism Diagnostic Observation Schedule-2 Module 4 diagnostic algorithm. This new algorithm, however, has not yet been validated in an independent sample without intellectual disability (ID). This multi-site study compared the original and revised algorithms in individuals with ASD without ID. The revised…

  3. Time-Resolved Spectroscopic Observation of Deposition Processes of Ultrananocrystalline Diamond/Amorphous Carbon Composite Films by Using a Coaxial Arc Plasma Gun

    NASA Astrophysics Data System (ADS)

    Hanada, Kenji; Yoshitake, Tsuyoshi; Nishiyama, Takashi; Nagayama, Kunihito

    2010-08-01

    The deposition of ultrananocrystalline diamond (UNCD)/amorphous carbon composite films using a coaxial arc plasma gun in vacuum and, for comparison, in a 53.3 Pa hydrogen atmosphere was spectroscopically observed using a high-speed camera equipped with narrow-band-pass filters. UNCD crystallites with diameters of approximately 1.6 nm were formed even in vacuum. These extremely small crystallites imply that the formation is predominantly due to nucleation without the subsequent growth. Even in vacuum, emissions from C+ ions, C atoms, and C2 dimers lasted for approximately 100 µs, although the emission lifetimes of these species are generally 10 ns. We consider that the nucleation is due to the supersaturated environment containing excited carbon species with large number densities.

  4. A nested multisite daily rainfall stochastic generation model

    NASA Astrophysics Data System (ADS)

    Srikanthan, Ratnasingham; Pegram, Geoffrey G. S.

    2009-06-01

    SummaryThis paper describes a nested multisite daily rainfall generation model which preserves the statistics at daily, monthly and annual levels of aggregation. A multisite two-part daily model is nested in multisite monthly, then annual models. A multivariate set of fourth order Markov chains is used to model the daily occurrence of rainfall; the daily spatial correlation in the occurrence process is handled by using suitably correlated uniformly distributed variates via a Normal Scores Transform (NST) obtained from a set of matched multinormal pseudo-random variates, following Wilks [Wilks, D.S., 1998. Multisite generalisation of a daily stochastic precipitation generation model. Journal of Hydrology 210, 178-191]; we call it a hidden covariance model. A spatially correlated two parameter gamma distribution is used to obtain the rainfall depths; these values are also correlated via a specially matched hidden multinormal process. For nesting, the generated daily rainfall sequences at all the sites are aggregated to monthly rainfall values and these values are modified by a set of lag-1 autoregressive multisite monthly rainfall models. The modified monthly rainfall values are aggregated to annual rainfall and these are then modified by a lag-1 autoregressive multisite annual model. This nesting process ensures that the daily, monthly and annual means and covariances are preserved. The model was applied to a region with 30 rainfall sites, one of the five sets reported by Srikanthan [Srikanthan, R., 2005. Stochastic Generation of Daily Rainfall Data at a Number of Sites. Technical Report 05/7, CRC for Catchment Hydrology. Monash University, 66p]. A comparison of the historical and generated statistics shows that the model preserves all the important characteristics of rainfall at the daily, monthly and annual time scales, including the spatial structure. There are some outstanding features that need to be improved: depths of rainfall on isolated wet days and

  5. Photometric and Spectroscopic Analysis of Classical Novae: An Examination of Their Observational Characteristics and Greater Astronomical Impact

    NASA Astrophysics Data System (ADS)

    Helton, Lorren Andrew

    2010-12-01

    Classical novae (CNe) are violent thermonuclear explosions arising on the surface of white dwarfs in binary systems and are contributors to the chemical evolution of the interstellar medium through the production and ejection of copious amounts of metal-rich material. Observations and modeling of CNe eruptions illuminate numerous fundamental processes of astrophysical interest, including non-equilibrium thermonuclear runaway, radiative processes in dynamic nebular environments, binary star interaction, as well as dust condensation and grain growth. Here I summarize key findings from selected Galactic CNe observed as part of a 5 year, panchromatic optical/infrared observing campaign using Spitzer, Gemini, and other ground based optical facilities. In particular, I present detailed analysis of nova V1065 Centauri, including photoionization analysis of the emission lines, which enabled the derivation of abundances in the ejecta, and radiative transport modeling of the dust emission features, which allowed determination of the composition and characteristics of the dust in this system. I present analysis of three novae, V1974 Cygni, V382 Velorum, and V1494 Aquilae, observed from 4.4--15.5 years after outburst, discuss the characteristics of the nebulae at these late times, and estimate the abundances in their ejecta. In the case of V1494 Aql, I also report the first detection of neon. Finally, I present observations of three novae, DZ Crucis, V2361 Cygni, and V2362 Cygni, that exhibited unidentified infrared (UIR) features in their mid-infrared spectra, which exhibited unusual characteristics. I relate these features to other dusty novae in which features with similar characteristics were observed, and discuss possible sources for the UIR carriers. Analysis of the data obtained in the CNe monitoring campaign presented here highlights the need for synoptic observations obtained with broad wavelength coverage. Observations of V1065 Cen, which exhibited spectra rich in

  6. The galaxy's 157 micron (C 2) emission: Observations by means of a spectroscopic lunar-occultation technique

    NASA Technical Reports Server (NTRS)

    Stacey, G. J.; Smyers, S. D.; Kurtz, N. T.; Harwit, M.

    1983-01-01

    Galactic (C II) 157 micron, fine-structure emission was estimated. At a Galactic longitude of 8 deg, the peak power observed in a 7' x 7' field is approx. 5 x 10 to the -9 Watt. The method used to detect this radiation involved chopping against the cold side of the Moon.

  7. High-dispersion spectroscopic observations of Venus during 1968 and 1969 II. The carbon-dioxide band at 8689A

    NASA Technical Reports Server (NTRS)

    Schorn, R. A. J.; Woszczyk, A.; Young, L. D. G.

    1974-01-01

    Thirty well-exposed photographic plates showing the spectrum of the carbon dioxide band at 8689A in the atmosphere of Venus were obtained during 1968 and 1969. All spectra were obtained at a dispersion of 2 A/mm for Venus phase angles varying from 10 deg. to 126 deg. Rotational temperatures ranging from 236 K to 274 K were found. The average value of the rotational temperature is 246 + or - 1 K (one standard deviation); for 1967 observations, the rotational temperatures ranged from 222 to 248 K, with an average value of 238 + or - 4 K. The variation of the equivalent width of the 8689A band, with Venus phase angle, was very similar for the two sets of observations (53 plates). The temporal variations, of approximately 30 percent, were comparable with the phase variations over this limited range of phase angle.

  8. Independent positioning of microelectrodes for multisite recordings in vitro.

    PubMed

    Albus, Klaus; Sinske, Kurt; Heinemann, Uwe

    2009-01-30

    A robust and easy to handle, inexpensive multisite recording system is described which allows independent positioning of several microelectrodes with high precision axial movement of each electrode. The basic units of the system are a manually operated manipulator for left-right and up-down movement and a micrometer for positioning in the direction of the micrometer axis. The micrometer is actuated with a DC-motor operated by a stand-alone controller module allowing for remote control of the motor in either step mode or continuous mode. The multisite recording system has been proven to allow stable simultaneous recordings of single unit and population activities, extracellular ion concentrations and intracellular potentials in organotypic hippocampal slice cultures (OHSCs) of rat. PMID:18822315

  9. Optimized multisite ventricular pacing in postoperative single-ventricle patients.

    PubMed

    Havalad, Vinod; Cabreriza, Santos E; Cheung, Eva W; Aponte-Patel, Linda; Wang, Alice; Cheng, Bin; Wang, Daniel Y; Silver, Eric; Bacha, Emile A; Spotnitz, Henry M

    2014-10-01

    Ventricular dyssynchrony is associated with morbidity and mortality after palliation of a single ventricle. The authors hypothesized that resynchronization with optimized temporary multisite pacing postoperatively would be safe, feasible, and effective. Pacing was assessed in the intensive care unit within the first 24 h after surgery. Two unipolar atrial pacing leads and four bipolar ventricular pacing leads were placed at standardized sites intraoperatively. Pacing was optimized to maximize mean arterial pressure. The protocol tested 11 combinations of the 4 different ventricular lead sites, 6 atrioventricular delays (50-150 ms), and 14 intraventricular delays. Optimal pacing settings were thus determined and ultimately compared in four configurations: bipolar, unipolar, single-site atrioventricular pacing, and intrinsic rhythm. Each patient was his or her own control, and all pacing comparisons were implemented in random sequence. Single-ventricle palliation was performed for 17 children ages 0-21 years. Pacing increased mean arterial pressure (MAP) versus intrinsic rhythm, with the following configurations: bipolar multisite pacing increased MAP by 2.2 % (67.7 ± 2.4 to 69.2 ± 2.4 mmHg; p = 0.013) and unipolar multisite pacing increased MAP by 2.8 % (67.7 ± 2.4 to 69.6 ± 2.7 mmHg; p = 0.002). Atrioventricular single-site pacing increased MAP by 2.1 % (67.7 ± 2.4 to 69.1 ± 2.5 mmHg: p = 0.02, insignificant difference under Bonferroni correction). The echocardiographic fractional area change in nine patients increased significantly only with unipolar pacing (32 ± 3.1 to 36 ± 4.2 %; p = 0.02). No study-related adverse events occurred. Multisite pacing optimization is safe and feasible in the early postoperative period after single-ventricle palliation, with improvements in mean arterial pressure and fractional area shortening. Further study to evaluate clinical benefits is required. PMID:24827078

  10. Proton adsorption onto alumina: extension of multisite complexation (MUSIC) theory

    SciTech Connect

    Nagashima, K.; Blum, F.D.

    1999-09-01

    The adsorption isotherm of protons onto a commercial {gamma}-alumina sample was determined in aqueous nitric acid with sodium nitrate as a background electrolyte. Three discrete regions could be discerned in the log-log plots of the proton isotherm determined at the solution pH 5 to 2. The multisite complexation (MUSIC) model was modified to analyze the simultaneous adsorption of protons onto various kinds of surface species.

  11. Proton Adsorption onto Alumina: Extension of Multisite Complexation (MUSIC) Theory.

    PubMed

    Nagashima; Blum

    1999-09-01

    The adsorption isotherm of protons onto a commercial gamma-alumina sample was determined in aqueous nitric acid with sodium nitrate as a background electrolyte. Three discrete regions could be discerned in the log-log plots of the proton isotherm determined at the solution pH 5 to 2. The multisite complexation (MUSIC) model was modified to analyze the simultaneous adsorption of protons onto various kinds of surface species. Copyright 1999 Academic Press. PMID:10441408

  12. {sup 13}C-METHYL FORMATE: OBSERVATIONS OF A SAMPLE OF HIGH-MASS STAR-FORMING REGIONS INCLUDING ORION-KL AND SPECTROSCOPIC CHARACTERIZATION

    SciTech Connect

    Favre, Cécile; Bergin, Edwin A.; Crockett, Nathan R.; Neill, Justin L.; Carvajal, Miguel; Field, David; Jørgensen, Jes K.; Bisschop, Suzanne E.; Brouillet, Nathalie; Despois, Didier; Baudry, Alain; Kleiner, Isabelle; Margulès, Laurent; Huet, Thérèse R.; Demaison, Jean E-mail: miguel.carvajal@dfa.uhu.es

    2015-01-01

    We have surveyed a sample of massive star-forming regions located over a range of distances from the Galactic center for methyl formate, HCOOCH{sub 3}, and its isotopologues H{sup 13}COOCH{sub 3} and HCOO{sup 13}CH{sub 3}. The observations were carried out with the APEX telescope in the frequency range 283.4-287.4 GHz. Based on the APEX observations, we report tentative detections of the {sup 13}C-methyl formate isotopologue HCOO{sup 13}CH{sub 3} toward the following four massive star-forming regions: Sgr B2(N-LMH), NGC 6334 IRS 1, W51 e2, and G19.61-0.23. In addition, we have used the 1 mm ALMA science verification observations of Orion-KL and confirm the detection of the {sup 13}C-methyl formate species in Orion-KL and image its spatial distribution. Our analysis shows that the {sup 12}C/{sup 13}C isotope ratio in methyl formate toward the Orion-KL Compact Ridge and Hot Core-SW components (68.4 ± 10.1 and 71.4 ± 7.8, respectively) are, for both the {sup 13}C-methyl formate isotopologues, commensurate with the average {sup 12}C/{sup 13}C ratio of CO derived toward Orion-KL. Likewise, regarding the other sources, our results are consistent with the {sup 12}C/{sup 13}C in CO. We also report the spectroscopic characterization, which includes a complete partition function, of the complex H{sup 13}COOCH{sub 3} and HCOO{sup 13}CH{sub 3} species. New spectroscopic data for both isotopomers H{sup 13}COOCH{sub 3} and HCOO{sup 13}CH{sub 3}, presented in this study, have made it possible to measure this fundamentally important isotope ratio in a large organic molecule for the first time.

  13. Chemical Reactions in Protoplanetary Disks and Possibility of Detecting H2O Snowline Using Spectroscopic Observations with ALMA

    NASA Astrophysics Data System (ADS)

    Notsu, S.; Nomura, H.; Ishimoto, D.; Walsh, C.; Honda, M.; Millar, T. J.

    2015-12-01

    We calculate chemical reactions and obtain abundance distribution of H2O gas. We confirm that the abundance of H2O is high not only in the region inside H2 O snowline near the equatorial plane but also in the hot surface layer of outer disk. We also calculate velocity profiles of H2O emission lines, and find that we can obtain the information of H2O snowline through investigating the profiles of some line transitions that have small Einstein A coefficient and large excitation energy. Some useful H2O emission lines exist at sub-millimeter wavelength and are observable with ALMA.

  14. NEAR-CONTEMPORANEOUS OPTICAL SPECTROSCOPIC AND INFRARED PHOTOMETRIC OBSERVATIONS OF CANDIDATE HERBIG Ae/Be STARS IN THE MAGELLANIC CLOUDS

    SciTech Connect

    Rush, Bradley W.; Bjorkman, Karen S.; Wisniewski, John P. E-mail: Karen.Bjorkman@utoledo.edu

    2011-08-15

    We present near-IR (J, H, Ks) photometry for 27 of the 28 candidate Herbig Ae/Be stars in the Small and Large Magellanic Clouds (SMC and LMC) identified via the EROS1 and EROS2 surveys as well as near-contemporaneous optical (H{alpha}) spectroscopy for 21 of these 28 candidates. Our observations extend previous efforts to determine the evolutionary status of these objects. We compare the IR brightness and colors of a subset of our sample with archival ground-based IR data and find evidence of statistically significant photometric differences for EROS LMC HAeBe candidates (ELHC) 5, 7, 12, 18, and 21 in one or more filters. In all cases, these near-IR photometric variations exhibit a gray color as compared to earlier epoch data. The {approx}1 mag IR brightening and minimal change in the H{alpha} emission strength we observe in ELHC 7 is consistent with previous claims that it is a UX Ori type HAe/Be star, which is occasionally obscured by dust clouds. We also detect a {approx}1 mag IR brightening of ELHC 12, but find little evidence of a similar large-scale change in its H{alpha} line strength, suggesting that its behavior could also be caused by a UX Ori-like event. The {approx}0.5 mag IR variability we observe for ELHC 21, which also exhibited little evidence of a change in its H{alpha} emission strength, could conceivably be caused by a major recent enhancement in the density of the inner disk region of a classical Be star. We also report the first near-IR photometry for two EROS SMC HAeBe Candidates (ESHC) stars and the first H{alpha} spectroscopy for one ELHC and five ESHC stars. Although H{alpha} emission is detected in all of these new observations, they do not exhibit a strong near-IR excess. It is therefore possible that many of these objects may be classical Be stars rather than Herbig Ae/Be stars.

  15. Dynamics of allosteric action in multisite protein modification

    NASA Astrophysics Data System (ADS)

    Milotti, Edoardo; Del Fabbro, Alessio; Dalla Pellegrina, Chiara; Chignola, Roberto

    2007-06-01

    Protein functions in cells may be activated or modified by the attachment of several kinds of chemical groups. While protein phosphorylation, i.e., the attachment of a phosphoryl (PO3-) group, is the most studied form of protein modification, and is known to regulate the functions of many proteins, protein behavior can also be modified by nitrosylation, acetylation, methylation, etc. A protein can have multiple modification sites, and displays some form of transition only when enough sites are modified. In a previous paper we have modeled the generic equilibrium properties of multisite protein modification [R. Chignola, C. Dalla Pellegrina, A. Del Fabbro, E. Milotti, Physica A 371 (2006) 463] and we have shown that it can account both for sharp, robust thresholds and for information transfer between processes with widely separated timescales. Here we use the same concepts to expand that analysis starting from a dynamical description of multisite modification: we give analytical results for the basic dynamics and numerical results in an example where the modification chain is cascaded with a Michaelis-Menten step. We modify the dynamics and analyze an example with realistic phosphorylation/dephosphorylation steps, and give numerical evidence of the independence of the allosteric effect from the details of the attachment-detachment processes. We conclude that multisite protein modification is dynamically equivalent to the classic allosteric effect.

  16. A new method of observing weak extended x-ray sources with the Reuven Ramaty high-energy solar spectroscopic imager.

    PubMed

    Hannah, Iain G; Hurford, Gordon J; Hudson, Hugh S; Lin, Robert P

    2007-02-01

    We present a new method, fan-beam modulation, for observing weak extended x-ray sources with the Reuven Ramaty High-Energy Solar Spectroscopic Imager (RHESSI). This space-based solar x-ray and gamma-ray telescope has much greater sensitivity than previous experiments in the 3-25 keV range, but is normally not well suited to detecting extended sources since their signal is not modulated by RHESSI's rotating grids. When the spacecraft is offpointed from the target source, however, the fan-beam modulation time-modulates the transmission by shadowing resulting from exploiting the finite thickness of the grids. In this article we detail how the technique is implemented and verify its consistency with sources with clear known signals that have occurred during RHESSI offpointing: microflares and the Crab Nebula. In both cases the results are consistent with previous and complementary measurements. Preliminary work indicates that this new technique allows RHESSI to observe the integrated hard x-ray spectrum of weak extended sources on the quiet Sun. PMID:17578130

  17. First spectroscopic observation of gold(i) butadiynylide: Photodetachment velocity map imaging of the AuC4H anion.

    PubMed

    Visser, Bradley R; Addicoat, Matthew A; Gascooke, Jason R; Lawrance, Warren D; Metha, Gregory F

    2016-07-28

    The velocity map imaging technique was used in the investigation of gold(i) butadiynylide, AuC4H(-), with images recorded at two excitation wavelengths. The resultant photodetachment spectra show a well defined vibrational progression in the neutral with an energy spacing of 343 ± 3 cm(-1). The adiabatic electron affinity was determined to be 1.775 ± 0.005 eV and assigned to the X(1)Σ(+)←X(2)Σ(+) transition between the anionic and neutral ground states. Franck-Condon simulations performed on density functional theory optimized geometries assisted the assignment of linear geometries to the neutral and anion and the observed vibrational progression to that of the Au-C4H stretch. PMID:27475374

  18. Compact Solar Spectroscopic Column CO2, CH4, H2O and HOD Observations: Performance Evaluation at TCCON Sites

    NASA Astrophysics Data System (ADS)

    Butterfield, Z.; Lindenmaier, R.; Dubey, M. K.; Hedelius, J.; Wunch, D.; Wennberg, P. O.; Podolske, J. R.; Iraci, L. T.; Hillyard, P. W.; Hase, F.

    2014-12-01

    Monitoring, reporting and verification (MRV) of natural sources and sinks and anthropogenic emission of carbon dioxide (CO2) and methane (CH4) are crucial to predict climate change and develop transparent accounting policies to contain climate forcing. Remote sensing technologies are beginning to monitor CO2 and CH4 from ground and space (OCO-2 and GOSAT) with solar spectroscopy enabling direct MRV. However, current ground based coverage is sparse due to the need for large and expensive high-resolution spectrometers that are part of the Total Column Carbon Observing Network (TCCON, Bruker 125HR). This limits our MRV and satellite validation abilities, both regionally and globally. There are striking monitoring gaps in Asia, South America and Africa where the CO2 emissions are growing and there is a large uncertainty in fluxes from land use change, biomass burning and rainforest vulnerability. To fill this gap we evaluate the precision, accuracy and stability of our new compact, affordable and easy to use low-resolution spectrometer (Bruker EM27SUN) by comparing it with the much larger high-resolution TCCON instruments for column CO2, CH4, H2O and HOD. Results from Four Corners, Los Alamos, Caltech and Dryden-Armstrong sites show that our EM27SUN captures the variability of the aforementioned constituents very well, but has low and high offsets for CO2 and CH4, respectively. These off-the-shelf spectrometers should dramatically expand the coverage of regional column CO2 and CH4 observations, particularly in gap regions that include the rainforest. We will present opportunities that we are exploring to help enable transparent and reliable MRV and measurement of the coupled water-carbon cycle in tropical ecosystems.

  19. Spectroscopic infrared ellipsometry

    NASA Astrophysics Data System (ADS)

    Roseler, A.

    1992-03-01

    The spectroscopic infrared ellipsometry (SIRE) by means of the combination of a photometric ellipsometer with a Fourier transform spectrometer is used to measure optical properties in the infrared. From the observed four Stokes parameters, the spectrum of the degree of polarization after the reflection at the sample is calculated and discussed.

  20. Observational and laboratory studies of optical properties of black and brown carbon particles in the atmosphere using spectroscopic techniques

    NASA Astrophysics Data System (ADS)

    Nakayama, Tomoki; Matsumi, Yutaka

    2015-04-01

    Light absorption and scattering by aerosols are as an important contributor to radiation balance in the atmosphere. Black carbon (BC) is considered to be the most potent light absorbing material in the visible region of the spectrum, although light absorbing organic carbon (brown carbon or BrC) and mineral dust may also act as sources of significant absorption, especially in the ultraviolet (UV) and shorter visible wavelength regions. The optical properties of such particles depend on wavelength, particle size and shape, morphology, coating, and complex refractive index (or chemical composition), and therefore accurate in situ measurements of the wavelength dependence of the optical properties of particles are needed. Recently, cavity ring-down spectroscopy (CRDS) and photoacoustic spectroscopy (PAS) have been used for the direct measurements of extinction and absorption coefficients of particles suspended in air. We have applied these techniques to the observational studies of optical properties of BC and BrC in an urban site in Japan and to the laboratory studies of optical properties of secondary organic aerosols (SOAs) generated from a variety of biogenic and anthropogenic volatile organic compounds and those of diesel exhaust particles (DEPs). In the presentation, the basic principles of these techniques and the results obtained in our studies and in the recent literatures will be overviewed. References Guo, X. et al., Measurement of the light absorbing properties of diesel exhaust particles using a three-wavelength photoacoustic spectrometer, Atmos. Environ., 94, 428-437 (2014). Nakayama, T. et al., Measurements of aerosol optical properties in central Tokyo during summertime using cavity ring-down spectroscopy: Comparison with conventional techniques, Atmos. Environ., 44, 3034-3042 (2010). Nakayama, T. et al., Laboratory studies on optical properties of secondary organic aerosols generated during the photooxidation of toluene and the ozonolysis of alpha

  1. Study of diatoms/aqueous solution interface. I. Acid-base equilibria and spectroscopic observation of freshwater and marine species

    NASA Astrophysics Data System (ADS)

    Gélabert, A.; Pokrovsky, O. S.; Schott, J.; Boudou, A.; Feurtet-Mazel, A.; Mielczarski, J.; Mielczarski, E.; Mesmer-Dudons, N.; Spalla, O.

    2004-10-01

    This work reports on a concerted study of diatom-water interfaces for two marine planktonic ( Thalassiosira weissflogii= TW, Skeletonema costatum= SC) and two freshwater periphytic species ( Achnanthidium minutissimum= AMIN, Navicula minima= NMIN). Proton surface adsorption was measured at 25°C, pH of 3 to 11 and ionic strength of 0.001 to 1.0 M via potentiometric titration using a limited residence time reactor. Electrophoretic mobility of living cells and their frustules was measured as a function of pH and ionic strength. Information on the chemical composition and molecular structure of diatoms surfaces was obtained using FT-IR (in situ attenuated total reflectance) and X-ray Photoelectron Spectroscopy (XPS). The surface area of living cells and their frustules in aqueous solutions was quantified using Small Angle X-ray Scattering Spectroscopy (SAXS). These observations allowed us to identify the nature and to determine the concentration of the major surface functional groups (carboxyl, amine and silanol) responsible for the amphoteric behavior of cell surfaces in aqueous solutions. Taking into account the relative proportion of surface sites inferred from XPS and FT-IR measurements, a surface complexation model of diatom-solution interfaces was generated on the basis of surface titration results. The cell-normalized ratios of the three major surface sites {>COOH}: {>NH 3}: {>SiOH} are 1:1:0.1, 1:10:0, 1:1:0.4 and 1:1:0.3 for TW, SC, AMIN and NMIN, respectively. The total amount of proton/hydroxyl active surface sites for investigated species ranges from 1 (NMIN) to 9 (SC) mmol/g dry weight. Normalization of these site densities to the area of siliceous skeleton yields values between 0.3 (NMIN) and 0.9 mmol/m 2 (SC) which are an order of magnitude higher than corresponding values for organic-free frustules or amorphous silica. This suggests that the amphoteric properties and possibly the affinity for metal adsorption of diatom cultures are essentially

  2. Unraveling the electronic structure of azolehemiporphyrazines: direct spectroscopic observation of magnetic dipole allowed nature of the lowest π-π* transition of 20π-electron porphyrinoids.

    PubMed

    Muranaka, Atsuya; Ohira, Shino; Toriumi, Naoyuki; Hirayama, Machiko; Kyotani, Fumiko; Mori, Yukie; Hashizume, Daisuke; Uchiyama, Masanobu

    2014-06-26

    Hemiporphyrazines are a large family of phthalocyanine analogues in which two isoindoline units are replaced by other rings. Here we report unambiguous identification of 20π-electron structure of triazolehemiporphyrazines (1, 2) and thiazolehemiporphyrazine (3) by means of X-ray analysis, various spectroscopic methods, and density functional theory (DFT) calculations. The hemiporphyrazines were compared in detail with dibenzotetraazaporphyrin (4), a structurally related 18π-electron molecule. X-ray analysis revealed that tetrakis(2,6-dimethylphenyloxy)triazolehemiporphyrazine (1b) adopted planar geometry in the solid state. A weak absorption band with a pronounced vibronic progression, observed for all the hemiporphyrazines, was attributed to the lowest π-π* transition with the electric-dipole-forbidden nature. In the case of intrinsically chiral vanadyl triazolehemiporphyrazine (2), a large dissymmetry (g) factor was detected for the CD signal corresponding to the lowest π-π* transition with the magnetic-dipole-allowed nature. Molecular orbital analysis and NICS calculations showed that the azolehemiporphyrazines have a 20π-electron system with a weak paratropic ring current. PMID:24866729

  3. Multi-Sited Global Ethnography and Travel: Gendered Journeys in Three Registers

    ERIC Educational Resources Information Center

    Epstein, Debbie; Fahey, Johannah; Kenway, Jane

    2013-01-01

    This paper joins a barely begun conversation about multi-sited and global ethnography in educational research; a conversation that is likely to intensify along with growing interest in the links between education, globalisation, internationalisation and transnationalism. Drawing on an ongoing multi-sited global ethnography of elite schools and…

  4. Multisite Image Data Collection and Management Using the RSNA Image Sharing Network

    PubMed Central

    Erickson, Bradley J; Fajnwaks, Patricio; Langer, Steve G; Perry, John

    2014-01-01

    The execution of a multisite trial frequently includes image collection. The Clinical Trials Processor (CTP) makes removal of protected health information highly reliable. It also provides reliable transfer of images to a central review site. Trials using central review of imaging should consider using CTP for handling image data when a multisite trial is being designed. PMID:24772205

  5. Spectroscopic Observations of the Planets

    NASA Technical Reports Server (NTRS)

    Owen, Tobias

    1998-01-01

    During the period under review, the main effort of the research supported by this grant was concentrated on Titan, Iapetus, and two comets, Comet Hyakutake and Comet Hale-Bopp. Significant discoveries were made in each case as summarized in the report.

  6. Hard X-ray Spectroscopic, Microwave and H-alpha Linear Polarization Studies with Hard X-Ray Observations from HESSI

    NASA Technical Reports Server (NTRS)

    Kiplinger, Alan L.

    2005-01-01

    The Principal Investigator (P.I.) has been pursuing a three year grant under NASA's Sun-Earth Connection Guest Investigator Program in support of the Ramaty High Energy Solar Spectroscopic Imager (RHESSI). An objective of these efforts is to combine X-ray and other data on solar flares, coronal mass ejections and interplanetary particle events in order to obtain a more comprehensive recognition of signatures, and understanding of interplanetary proton events. Thus, part of these efforts are to investigate if signatures seen in hard X-rays and microwaves can lead to better predictions of interplanetary proton events that can be dangerous to astronauts and spacecraft. The original proposal was written in May, 2000 and it discusses a three-pronged approach for data comparisons with three new types of instrumentation observing at X-ray, microwave and optical wavelengths. The major impetus behind this work and the proposal is that the P.I. discovered a strong correlation between a particular type of hard X-ray signature seen in spectral evolutions and interplanetary proton events (Kiplinger, 1995). The basic signature is that hard X-ray flux peaks either exhibit spectra that soften on their decays (Le. show fewer and fewer high energy X-rays with time) or they harden during decays (i.e. high energy X-rays decay significantly slower that lower energy X-rays). This signature is called progressive hardening. Studies were conducted over an eight-year period of data from the Hard X-Ray Burst Spectrometer (HXRBS) of the Solar maximum mission. Out of the 750 well observed flares studied, 41 flares had major associated proton events. Of these, 29 events were predicted on the basis of progressive hardening for a hit rate of 71%. The 152 largest flares had a hit rate of 82%.

  7. Candidate Water Vapor Lines to Locate the H2O Snowline through High-dispersion Spectroscopic Observations. I. The Case of a T Tauri Star

    NASA Astrophysics Data System (ADS)

    Notsu, Shota; Nomura, Hideko; Ishimoto, Daiki; Walsh, Catherine; Honda, Mitsuhiko; Hirota, Tomoya; Millar, T. J.

    2016-08-01

    Inside the H2O snowline of protoplanetary disks, water evaporates from the dust-grain surface into the gas phase, whereas it is frozen out onto the dust in the cold region beyond the snowline. H2O ice enhances the solid material in the cold outer part of a disk, which promotes the formation of gas-giant planet cores. We can regard the H2O snowline as the surface that divides the regions between rocky and gaseous giant planet formation. Thus observationally measuring the location of the H2O snowline is crucial for understanding the planetesimal and planet formation processes, and the origin of water on Earth. In this paper, we find candidate water lines to locate the H2O snowline through future high-dispersion spectroscopic observations. First, we calculate the chemical composition of the disk and investigate the abundance distributions of H2O gas and ice, and the position of the H2O snowline. We confirm that the abundance of H2O gas is high not only in the hot midplane region inside the H2O snowline but also in the hot surface layer of the outer disk. Second, we calculate the H2O line profiles and identify those H2O lines that are promising for locating the H2O snowline: the identified lines are those that have small Einstein A coefficients and high upper state energies. The wavelengths of the candidate H2O lines range from mid-infrared to sub-millimeter, and they overlap with the regions accessible to the Atacama Large Millimeter/sub-millimeter Array and future mid-infrared high-dispersion spectrographs (e.g., TMT/MICHI, SPICA).

  8. Multisite surface electromyography and complementary healing intervention: a comparative analysis.

    PubMed

    Wirth, D P; Cram, J R

    1997-01-01

    A comparative analysis was conducted on a series of three experimental studies that examined the effect of various local and nonlocal (distant) complementary healing methods on multisite surface electromyographic (sEMG) and autonomic measures. The series concentrated sEMG electrode placement on specific neuromuscular paraspinal centers (cervical [C4], thoracic [T6], and lumbar [L3]), along with the frontalis region, due to the fact that these sites corresponded to the location of individual chakra centers as delineated in ancient Eastern medical and philosophical texts. It was hypothesized that the sEMG assessment procedure had the potential to provide objective, quantifiable correlates for complementary healing treatment effects, as well as assess the energy flow through the chakras during a healing treatment. The studies were the first of their kind to incorporate randomized, double-blind, placebo-controlled protocols in order to evaluate correlative neuromuscular multisite sEMG paraspinal measures with different complementary healing treatment interventions. Although the measurement protocols were similar between experiments, the results, demonstrated by the individual studies, varied. Whereas the overall findings of the series are encouraging because they indicate a potential objective scientific correlate to complementary healing treatment intervention, the results are considered preliminary in nature and appear to be linked to either the meditational experience of the subjects or dependent on the particular healer(s) used. Additional research is needed in order to establish the multisite sEMG assessment procedure as a reliable correlative measure for complementary healing treatment effects and to determine whether a consistent replicative treatment effect can be demonstrated independent of the specific subject population or practitioner(s) used. PMID:9449057

  9. Effective interactions in multisite cells for adsorption in microporous materials

    NASA Astrophysics Data System (ADS)

    Demontis, Pierfranco; Pazzona, Federico G.; Suffritti, Giuseppe B.

    2009-04-01

    Local, discrete models of self-interacting multisite adsorption cells have been shown to be able to provide a coarse-grained representation of equilibrium properties of small molecules adsorbed in nanoporous materials at the mesoscopic scale. In the present work we show how the essential statistical properties of a host cell of structured sites with multiple adsorption energies and particle-particle interactions (that is the partition function, the average energy, and the average number of guests close to the windows connecting the cell to its surroundings) can be reproduced by a less-structured cell with two occupancy-dependent adsorption energy levels.

  10. Lessons Learned From an International, Multisite Simulation Research Study.

    PubMed

    Foronda, Cynthia; Alhusen, Jeanne

    2016-01-01

    The purpose of this article is to describe the process and lessons learned in conducting an international, multisite simulation research study. Key lessons include asking site leaders to complete human subjects training early, applying for a deferral agreement for multiple sites, standardization, seeking consultation, considering differences in simulation centers, and having a back-up plan if committed team members are unable to progress. Although challenging, this process yields many rewards and raises the state of the science to improve pedagogy and student learning outcomes. PMID:26779693

  11. Spectroscopic Observations of SN 2012fr: A Luminous, Normal Type Ia Supernova with Early High-velocity Features and a Late Velocity Plateau

    NASA Astrophysics Data System (ADS)

    Childress, M. J.; Scalzo, R. A.; Sim, S. A.; Tucker, B. E.; Yuan, F.; Schmidt, B. P.; Cenko, S. B.; Silverman, J. M.; Contreras, C.; Hsiao, E. Y.; Phillips, M.; Morrell, N.; Jha, S. W.; McCully, C.; Filippenko, A. V.; Anderson, J. P.; Benetti, S.; Bufano, F.; de Jaeger, T.; Forster, F.; Gal-Yam, A.; Le Guillou, L.; Maguire, K.; Maund, J.; Mazzali, P. A.; Pignata, G.; Smartt, S.; Spyromilio, J.; Sullivan, M.; Taddia, F.; Valenti, S.; Bayliss, D. D. R.; Bessell, M.; Blanc, G. A.; Carson, D. J.; Clubb, K. I.; de Burgh-Day, C.; Desjardins, T. D.; Fang, J. J.; Fox, O. D.; Gates, E. L.; Ho, I.-T.; Keller, S.; Kelly, P. L.; Lidman, C.; Loaring, N. S.; Mould, J. R.; Owers, M.; Ozbilgen, S.; Pei, L.; Pickering, T.; Pracy, M. B.; Rich, J. A.; Schaefer, B. E.; Scott, N.; Stritzinger, M.; Vogt, F. P. A.; Zhou, G.

    2013-06-01

    We present 65 optical spectra of the Type Ia SN 2012fr, 33 of which were obtained before maximum light. At early times, SN 2012fr shows clear evidence of a high-velocity feature (HVF) in the Si II λ6355 line that can be cleanly decoupled from the lower velocity "photospheric" component. This Si II λ6355 HVF fades by phase -5 subsequently, the photospheric component exhibits a very narrow velocity width and remains at a nearly constant velocity of ~12,000 km s-1 until at least five weeks after maximum brightness. The Ca II infrared triplet exhibits similar evidence for both a photospheric component at v ≈ 12,000 km s-1 with narrow line width and long velocity plateau, as well as an HVF beginning at v ≈ 31,000 km s-1 two weeks before maximum. SN 2012fr resides on the border between the "shallow silicon" and "core-normal" subclasses in the Branch et al. classification scheme, and on the border between normal and high-velocity Type Ia supernovae (SNe Ia) in the Wang et al. system. Though it is a clear member of the "low velocity gradient" group of SNe Ia and exhibits a very slow light-curve decline, it shows key dissimilarities with the overluminous SN 1991T or SN 1999aa subclasses of SNe Ia. SN 2012fr represents a well-observed SN Ia at the luminous end of the normal SN Ia distribution and a key transitional event between nominal spectroscopic subclasses of SNe Ia.

  12. Multisite multivariate modeling of daily precipitation and temperature in the Canadian Prairie Provinces using generalized linear models

    NASA Astrophysics Data System (ADS)

    Asong, Zilefac E.; Khaliq, M. N.; Wheater, H. S.

    2016-02-01

    Based on the Generalized Linear Model (GLM) framework, a multisite stochastic modelling approach is developed using daily observations of precipitation and minimum and maximum temperatures from 120 sites located across the Canadian Prairie Provinces: Alberta, Saskatchewan and Manitoba. Temperature is modeled using a two-stage normal-heteroscedastic model by fitting mean and variance components separately. Likewise, precipitation occurrence and conditional precipitation intensity processes are modeled separately. The relationship between precipitation and temperature is accounted for by using transformations of precipitation as covariates to predict temperature fields. Large scale atmospheric covariates from the National Center for Environmental Prediction Reanalysis-I, teleconnection indices, geographical site attributes, and observed precipitation and temperature records are used to calibrate these models for the 1971-2000 period. Validation of the developed models is performed on both pre- and post-calibration period data. Results of the study indicate that the developed models are able to capture spatiotemporal characteristics of observed precipitation and temperature fields, such as inter-site and inter-variable correlation structure, and systematic regional variations present in observed sequences. A number of simulated weather statistics ranging from seasonal means to characteristics of temperature and precipitation extremes and some of the commonly used climate indices are also found to be in close agreement with those derived from observed data. This GLM-based modelling approach will be developed further for multisite statistical downscaling of Global Climate Model outputs to explore climate variability and change in this region of Canada.

  13. A queueing approach to multi-site enzyme kinetics

    PubMed Central

    Hochendoner, Philip; Ogle, Curtis; Mather, William H.

    2014-01-01

    Multi-site enzymes, defined as where multiple substrate molecules can bind simultaneously to the same enzyme molecule, play a key role in a number of biological networks, with the Escherichia coli protease ClpXP a well-studied example. These enzymes can form a low latency ‘waiting line’ of substrate to the enzyme's catalytic core, such that the enzyme molecule can continue to collect substrate even when the catalytic core is occupied. To understand multi-site enzyme kinetics, we study a discrete stochastic model that includes a single catalytic core fed by a fixed number of substrate binding sites. A natural queueing systems analogy is found to provide substantial insight into the dynamics of the model. From this, we derive exact results for the probability distribution of the enzyme configuration and for the distribution of substrate departure times in the case of identical but distinguishable classes of substrate molecules. Comments are also provided for the case when different classes of substrate molecules are not processed identically. PMID:24904740

  14. Spectroscopic Binary Stars

    NASA Astrophysics Data System (ADS)

    Batten, A.; Murdin, P.

    2000-11-01

    Historically, spectroscopic binary stars were binary systems whose nature was discovered by the changing DOPPLER EFFECT or shift of the spectral lines of one or both of the component stars. The observed Doppler shift is a combination of that produced by the constant RADIAL VELOCITY (i.e. line-of-sight velocity) of the center of mass of the whole system, and the variable shift resulting from the o...

  15. The s-process in low-metallicity stars - II. Interpretation of high-resolution spectroscopic observations with asymptotic giant branch models

    NASA Astrophysics Data System (ADS)

    Bisterzo, S.; Gallino, R.; Straniero, O.; Cristallo, S.; Käppeler, F.

    2011-11-01

    High-resolution spectroscopic observations of 100 metal-poor carbon and s-rich stars (CEMP-s) collected from the literature are compared with the theoretical nucleosynthesis models of the asymptotic giant branch (AGB) presented in Paper I (MAGBini= 1.3, 1.4, 1.5, 2 M⊙, - 3.6 ≲ [ Fe/H ] ≲- 1.5). The s-process enhancement detected in these objects is associated with binary systems: the more massive companion evolved faster through the thermally pulsing AGB phase (TP-AGB), synthesizing s-elements in the inner He intershell, which are partly dredged up to the surface during the third dredge-up (TDU) episode. The secondary observed low-mass companion became CEMP-s by the mass transfer of C- and s-rich material from the primary AGB. We analyse the light elements C, N, O, Na and Mg, as well as the two s-process indicators, [hs/ls] (where ls = is the the light-s peak at N = 50 and hs = the heavy-s peak at N = 82) and [Pb/hs]. We distinguish between CEMP-s with high s-process enhancement, [hs/Fe] >rsim 1.5 (CEMP-sII), and mild s-process enhanced stars, [hs/Fe] < 1.5 (CEMP-sI). To interpret the observations, a range of s-process efficiencies at any given metallicity is necessary. This is confirmed by the high spread observed in [Pb/hs] (˜2 dex). A degeneration of solutions is found with some exceptions: most main-sequence CEMP-sII stars with low [Na/Fe] can only be interpreted with MAGBini= 1.3-1.4 M⊙. Giants having suffered the first dredge-up (FDU) need a dilution >rsim1 dex (dil is defined as the mass of the convective envelope of the observed star, Mobs★, over the material transferred from the AGB to the companion, MtransAGB). Then AGB models with higher AGB initial masses (MAGBini= 1.5-2 M⊙) are adopted to interpret CEMP-sII giants. In general, solutions with AGB models in the mass range MAGBini= 1.3-2 M⊙ and different dilution factors are found for CEMP-sI stars. About half of the CEMP-s stars with europium measurements show a high r

  16. Deciphering the Interplay among Multisite Phosphorylation, Interaction Dynamics, and Conformational Transitions in a Tripartite Protein System

    PubMed Central

    2016-01-01

    Multisite phosphorylation is a common pathway to regulate protein function, activity, and interaction pattern in vivo, but routine biochemical analysis is often insufficient to identify the number and order of individual phosphorylation reactions and their mechanistic impact on the protein behavior. Here, we integrate complementary mass spectrometry (MS)-based approaches to characterize a multisite phosphorylation-regulated protein system comprising Polo-like kinase 1 (Plk1) and its coactivators Aurora kinase A (Aur-A) and Bora, the interplay of which is essential for mitotic entry after DNA damage-induced cell cycle arrest. Native MS and cross-linking–MS revealed that Aur-A/Bora-mediated Plk1 activation is accompanied by the formation of Aur-A/Bora and Plk1/Bora heterodimers. We found that the Aur-A/Bora interaction is independent of the Bora phosphorylation state, whereas the Plk1/Bora interaction is dependent on extensive Bora multisite phosphorylation. Bottom-up and top-down proteomics analyses showed that Bora multisite phosphorylation proceeds via a well-ordered sequence of site-specific phosphorylation reactions, whereby we could reveal the involvement of up to 16 phosphorylated Bora residues. Ion mobility spectrometry–MS demonstrated that this multisite phosphorylation primes a substantial structural rearrangement of Bora, explaining the interdependence between extensive Bora multisite phosphorylation and Plk1/Bora complex formation. These results represent a first benchmark of our multipronged MS strategy, highlighting its potential to elucidate the mechanistic and structural implications of multisite protein phosphorylation. PMID:27504491

  17. High-resolution spectroscopic observations of binary stars and yellow stragglers in three open clusters: NGC 2360, NGC 3680, and NGC 5822

    SciTech Connect

    Sales Silva, J. V.; Peña Suárez, V. J.; Katime Santrich, O. J.; Pereira, C. B.; Drake, N. A.; Roig, F. E-mail: jearim@on.br E-mail: claudio@on.br E-mail: froig@on.br

    2014-11-01

    Binary stars in open clusters are very useful targets in constraining the nucleosynthesis process. The luminosities of the stars are known because the distances of the clusters are also known, so chemical peculiarities can be linked directly to the evolutionary status of a star. In addition, binary stars offer the opportunity to verify a relationship between them and the straggler population in both globular and open clusters. We carried out a detailed spectroscopic analysis to derive the atmospheric parameters for 16 red giants in binary systems and the chemical composition of 11 of them in the open clusters NGC 2360, NGC 3680, and NGC 5822. We obtained abundances of C, N, O, Na, Mg, Al, Ca, Si, Ti, Ni, Cr, Y, Zr, La, Ce, and Nd. The atmospheric parameters of the studied stars and their chemical abundances were determined using high-resolution optical spectroscopy. We employ the local thermodynamic equilibrium model atmospheres of Kurucz and the spectral analysis code MOOG. The abundances of the light elements were derived using the spectral synthesis technique. We found that the stars NGC 2360-92 and 96, NGC 3680-34, and NGC 5822-4 and 312 are yellow straggler stars. We show that the spectra of NGC 5822-4 and 312 present evidence of contamination by an A-type star as a secondary star. For the other yellow stragglers, evidence of contamination is given by the broad wings of the Hα. Detection of yellow straggler stars is important because the observed number can be compared with the number predicted by simulations of binary stellar evolution in open clusters. We also found that the other binary stars are not s-process enriched, which may suggest that in these binaries the secondary star is probably a faint main-sequence object. The lack of any s-process enrichment is very useful in setting constraints for the number of white dwarfs in the open cluster, a subject that is related to the birthrate of these kinds of stars in open clusters and also to the age of a

  18. Multi-site identification of a distributed hydrological nitrogen model using Bayesian uncertainty analysis

    NASA Astrophysics Data System (ADS)

    Jiang, Sanyuan; Jomaa, Seifeddine; Büttner, Olaf; Meon, Günter; Rode, Michael

    2015-10-01

    For capturing spatial variations of runoff and nutrient fluxes attributed to catchment heterogeneity, multi-site hydrological water quality monitoring strategies are increasingly put into practice. This study aimed to investigate the impacts of spatially distributed streamflow and streamwater Inorganic Nitrogen (IN) concentration observations on the identification of a continuous time, spatially semi-distributed and process-based hydrological water quality model HYPE (HYdrological Predictions for the Environment). A Bayesian inference based approach DREAM(ZS) (DiffeRential Evolution Adaptive Metrololis algorithm) was combined with HYPE to implement model optimisation and uncertainty analysis on streamflow and streamwater IN concentration simulations at a nested meso scale catchment in central Germany. To this end, a 10-year period (1994-1999 for calibration and 1999-2004 for validation) was utilised. We compared the parameters' posterior distributions, modelling performance using the best estimated parameter set and 95% prediction confidence intervals at catchment outlet for the calibration period that were derived from single-site calibration (SSC) and multi-site calibration (MSC) modes. For SSC, streamflow and streamwater IN concentration observations at only the catchment outlet were used. While, for MSC, streamflow and streamwater IN concentration observations from both catchment outlet and two internal sites were considered. Results showed that the uncertainty intervals of hydrological water quality parameters' posterior distributions estimated from MSC, were narrower than those obtained from SSC. In addition, it was found that the MSC outperformed SSC on streamwater IN concentration simulations at internal sites for both calibration and validation periods, while the influence on streamflow modelling performance was small. This can be explained by the "nested" nature of the catchment and high correlation between discharge observations from different sites

  19. In-Situ Measurements of HCN and CH3CN in the Pacific Troposphere: Sources, Sinks, and Comparisons with Spectroscopic Observations

    NASA Technical Reports Server (NTRS)

    Singh, Hanwant B.; Salas, L.; Herlth, D.; Czech, E.; Viezee, W.; Li, Q.; Jacob, D. J.; Blake, D.; Sachse, G.; Harward, C. N.; Hipskind, R. Stephen (Technical Monitor)

    2002-01-01

    We report the first in-situ measurements of hydrogen cyanide (HCN) and acetonitrile (CH3CN) from the Pacific troposphere (0-12 km) obtained during the NASA/Trace-P mission (Feb.-April, 2001). Mean HCN and CH3CN mixing ratios of 243 (+/-118) ppt and 149 (+/-56) ppt respectively, were measured. The in-situ observations correspond to a total HCN column of 4.4-4.9 x 10(exp 15) molec. cm(exp -2) and a CH3CN column of 2.8-3.0 x 10(exp 15) molec. cm(exp -2). This HCN column is in good agreement with available spectroscopic observations. The atmospheric concentrations of HCN and CH3CN were greatly influenced by outflow of pollution from Asia. There is a linear relationship between the mixing ratios of HCN and CH3CN, and in turn these are well correlated with tracers of biomass combustion (e.g. CH3Cl, CO). Relative enhancements with respect to known tracers of biomass combustion within selected plumes in the free troposphere, and pollution episodes in the boundary layer allow an estimation of a global biomass burning source of 0.8+/-0.4 Tg (N)/y for HCN and 0.4+/-0.1 Tg (N)/y for CH3CN. In comparison, emissions from automobiles and industry are quite small (<0.05 Tg (N)/y). The vertical structure of HCN and CH3CN indicated reduced mixing ratios in the MBL (Marine Boundary Layer). Using, a simple box model, the observed gradients across the top of the MBL are used to derive an oceanic flux of 6.7 x 10(exp -15) g (N) cm(exp -2)/s for HCN and 4.8 x 10(exp -15) g (N) cm(exp -2)/s for CH3CN. An air-sea exchange model is used to conclude that this flux can be maintained if the oceans are under-saturated in HCN and CH3CN by 23% and 17%, respectively. It is inferred that oceanic loss is a dominant sink for these nitrites, and they deposit some 1.3 Tg (N) of nitrogen annually to the oceans. Assuming reaction with OH radicals and loss to the oceans as the major removal processes, a mean atmospheric residence time of 4.7 months for HCN and 5.1 months for CH3CN is calculated. A global

  20. Spectroscopic pulsational frequency identification and mode determination of γ Doradus star HD 12901

    NASA Astrophysics Data System (ADS)

    Brunsden, E.; Pollard, K. R.; Cottrell, P. L.; Wright, D. J.; De Cat, P.

    2012-12-01

    Using multisite spectroscopic data collected from three sites, the frequencies and pulsational modes of the γ Doradus star HD 12901 were identified. A total of six frequencies in the range 1-2 d-1 were observed, their identifications supported by multiple line-profile measurement techniques and previously published photometry. Five frequencies were of sufficient signal-to-noise ratio for mode identification, and all five displayed similar three-bump standard deviation profiles which were fitted well with (l,m) = (1,1) modes. These fits had reduced χ2 values of less than 18. We propose that this star is an excellent candidate to test models of non-radially pulsating γ Doradus stars as a result of the presence of multiple (1,1) modes. This paper includes data taken at the Mount John University Observatory of the University of Canterbury (New Zealand), the McDonald Observatory of the University of Texas at Austin (Texas, USA) and the European Southern Observatory at La Silla (Chile).

  1. Spectroscopic parallaxes of MAP region stars from UBVRI, DDO, and uvbyH-beta photometry. [Multichannel Astrometric Photometer for astronomical observation

    NASA Technical Reports Server (NTRS)

    Persinger, Tim; Castelaz, Michael W.

    1990-01-01

    This paper presents the results of spectral type and luminosity classification of reference stars in the Allegheny Observatory MAP parallax program, using broadband and intermediate-band photometry. In addition to the use of UBVRI and DDO photometric systems, the uvbyH-beta photometric system was included for classification of blue (B - V less than 0.6) reference stars. The stellar classifications made from the photometry are used to determine spectroscopic parallaxes. The spectroscopic parallaxes are used in turn to adjust the relative parallaxes measured with the MAP to absolute parallaxes. A new method for dereddening stars using more than one photometric system is presented. In the process of dereddening, visual extinctions, spectral types, and luminosity classes are determined, as well as a measure of the goodness of fit. The measure of goodness of fit quantifies confidence in the stellar classifications. It is found that the spectral types are reliable to within 2.5 spectral subclasses.

  2. Multisite Pacing for Cardiac Resynchronization Therapy: Promise and Pitfalls.

    PubMed

    Antoniadis, Antonios P; Behar, Jonathan M; Claridge, Simon; Jackson, Tom; Sohal, Manav; Rinaldi, Christopher Aldo

    2016-07-01

    Cardiac resynchronization therapy (CRT) reduces the morbidity and mortality of patients with symptomatic heart failure and intraventricular conduction delay. However, its clinical outcomes are non-uniform and up to one third of treated patients are subsequently classified as non-responders. Multisite pacing (MSP), i.e. stimulating the myocardium from multiple locations, has emerged as a potential therapeutic option in patients requiring CRT. The rationale for MSP is based on the hypothesis that increasing the pacing locations in the left ventricle results in a more physiologic and coordinated myocardial systole. MSP can be achieved by additional leads in the right or left ventricle but this can lead to high battery drain and more frequent generator replacements. Multipolar left ventricular leads can deliver pacing at multiple sites, and therefore, a single lead can be used for MSP. However, the optimal programming settings and the outcomes of this approach remain yet to be determined. PMID:27216844

  3. Four-dimensional multi-site two-photon excitation

    NASA Astrophysics Data System (ADS)

    Daria, Vincent R.; Stricker, Christian; Bowman, Richard; Bachor, Hans-A.; Redman, Stephen

    2010-02-01

    We use the holographic method to project an arbitrary array of diffraction-limited focal spots suitable for multi-site twophoton excitation. The spot array can be projected arbitrarily within a three-dimensional (3D) volume, while the fourth dimension in time is attributed to high temporal resolution via high-speed non-iterative calculation of the hologram using a video graphics accelerator board. We show that the spots have sufficient energy and spatiotemporal photon density for localized two-photon excitation at individual spots in the array. The significance of this work points to 3D microscopy, non-linear micro-fabrication, volume holographic optical storage and biomedical instrumentation. In neuroscience, timecritical release of neurotransmitters at multiple sites within complex dendritic trees of neurons can lead to insights on the mechanisms of information processing in the brain.

  4. Power estimation for non-standardized multisite studies.

    PubMed

    Keshavan, Anisha; Paul, Friedemann; Beyer, Mona K; Zhu, Alyssa H; Papinutto, Nico; Shinohara, Russell T; Stern, William; Amann, Michael; Bakshi, Rohit; Bischof, Antje; Carriero, Alessandro; Comabella, Manuel; Crane, Jason C; D'Alfonso, Sandra; Demaerel, Philippe; Dubois, Benedicte; Filippi, Massimo; Fleischer, Vinzenz; Fontaine, Bertrand; Gaetano, Laura; Goris, An; Graetz, Christiane; Gröger, Adriane; Groppa, Sergiu; Hafler, David A; Harbo, Hanne F; Hemmer, Bernhard; Jordan, Kesshi; Kappos, Ludwig; Kirkish, Gina; Llufriu, Sara; Magon, Stefano; Martinelli-Boneschi, Filippo; McCauley, Jacob L; Montalban, Xavier; Mühlau, Mark; Pelletier, Daniel; Pattany, Pradip M; Pericak-Vance, Margaret; Cournu-Rebeix, Isabelle; Rocca, Maria A; Rovira, Alex; Schlaeger, Regina; Saiz, Albert; Sprenger, Till; Stecco, Alessandro; Uitdehaag, Bernard M J; Villoslada, Pablo; Wattjes, Mike P; Weiner, Howard; Wuerfel, Jens; Zimmer, Claus; Zipp, Frauke; Hauser, Stephen L; Oksenberg, Jorge R; Henry, Roland G

    2016-07-01

    A concern for researchers planning multisite studies is that scanner and T1-weighted sequence-related biases on regional volumes could overshadow true effects, especially for studies with a heterogeneous set of scanners and sequences. Current approaches attempt to harmonize data by standardizing hardware, pulse sequences, and protocols, or by calibrating across sites using phantom-based corrections to ensure the same raw image intensities. We propose to avoid harmonization and phantom-based correction entirely. We hypothesized that the bias of estimated regional volumes is scaled between sites due to the contrast and gradient distortion differences between scanners and sequences. Given this assumption, we provide a new statistical framework and derive a power equation to define inclusion criteria for a set of sites based on the variability of their scaling factors. We estimated the scaling factors of 20 scanners with heterogeneous hardware and sequence parameters by scanning a single set of 12 subjects at sites across the United States and Europe. Regional volumes and their scaling factors were estimated for each site using Freesurfer's segmentation algorithm and ordinary least squares, respectively. The scaling factors were validated by comparing the theoretical and simulated power curves, performing a leave-one-out calibration of regional volumes, and evaluating the absolute agreement of all regional volumes between sites before and after calibration. Using our derived power equation, we were able to define the conditions under which harmonization is not necessary to achieve 80% power. This approach can inform choice of processing pipelines and outcome metrics for multisite studies based on scaling factor variability across sites, enabling collaboration between clinical and research institutions. PMID:27039700

  5. Efficient Calculations with Multisite Local Orbitals in a Large-Scale DFT Code CONQUEST.

    PubMed

    Nakata, Ayako; Bowler, David R; Miyazaki, Tsuyoshi

    2014-11-11

    Multisite local orbitals, which are formed from linear combinations of pseudoatomic orbitals from a target atom and its neighbor atoms, have been introduced in the large-scale density functional theory calculation code CONQUEST. Multisite local orbitals correspond to local molecular orbitals so that the number of required local orbitals can be minimal. The multisite support functions are determined by using the localized filter diagonalization (LFD) method [ Phys. Rev. B 2009 , 80 , 205104 ]. Two new methods, the double cutoff method and the smoothing method, are introduced to the LFD method to improve efficiency and stability. The Hamiltonian and overlap matrices with multisite local orbitals are constructed by efficient sparse-matrix multiplications in CONQUEST. The investigation of the calculated energetic and geometrical properties and band structures of bulk Si, Al, and DNA systems demonstrate the accuracy and the computational efficiency of the present method. The representability of both occupied and unoccupied band structures with the present method has been also confirmed. PMID:26584368

  6. Spectroscopically Unlocking Exoplanet Characteristics

    NASA Astrophysics Data System (ADS)

    Lewis, Nikole

    2016-05-01

    Spectroscopy plays a critical role in a number of areas of exoplanet research. The first exoplanets were detected by precisely measuring Doppler shifts in high resolution (R ~ 100,000) stellar spectra, a technique that has become known as the Radial Velocity (RV) method. The RV method provides critical constraints on exoplanet masses, but is currently limited to some degree by robust line shape predictions. Beyond the RV method, spectroscopy plays a critical role in the characterization of exoplanets beyond their mass and radius. The Hubble Space Telescope has spectroscopically observed the atmospheres of exoplanets that transit their host stars as seen from Earth giving us key insights into atmospheric abundances of key atomic and molecular species as well as cloud optical properties. Similar spectroscopic characterization of exoplanet atmospheres will be carried out at higher resolution (R ~ 100-3000) and with broader wavelength coverage with the James Webb Space Telescope. Future missions such as WFIRST that seek to the pave the way toward the detection and characterization of potentially habitable planets will have the capability of directly measuring the spectra of exoplanet atmospheres and potentially surfaces. Our ability to plan for and interpret spectra from exoplanets relies heavily on the fidelity of the spectroscopic databases available and would greatly benefit from further laboratory and theoretical work aimed at optical properties of atomic, molecular, and cloud/haze species in the pressure and temperature regimes relevant to exoplanet atmospheres.

  7. The value and potential of multisited ethnography for science education research: a review of Jrène Rahm's Science in the Making at the Margin

    NASA Astrophysics Data System (ADS)

    Beeman-Cadwallader, Nicole

    2012-03-01

    Rahm sought to illuminate how children and youth make meaning of science in three out-of-school time programs, and the identity work that is done through the trajectory of their youth toward their young adulthood. Through using multisited ethnography, she asserts that we can learn more about what the youth say about their science learning and science literacy development in these programs. She has revealed through her rich data the potential value of multisited ethnography for science education research. A similar theme of insider/outsider status to science emerged in each of the three sites. The nature of the data collected in Rahm's multisited ethnography allowed for the unveiling of the similarities in this theme, but also made evident the nuanced ways that this theme presented itself differently across the three sites. The additional potential came through in the varied data Rahm could have delved into and did not. A unique characteristic of ethnographic research, that is not necessarily present in other research methods, is that a wide array of varied data is collected. An analysis of documents, images, and observational field notes, which go beyond interview data, may provide deeper understandings previously untouched in science education.

  8. Increased free-water in the substantia nigra of Parkinson’s disease: a single-site and multi-site study

    PubMed Central

    Ofori, E.; Pasternak, O.; Planetta, P.J.; Burciu, R.; Snyder, A.; Febo, M.; Golde, T.E.; Okun, M.S.; Vaillancourt, D.E.

    2014-01-01

    Measures from diffusion magnetic resonance imaging reflect changes in the substantia nigra of Parkinson’s disease. It is the case, however, that partial volume effects from free-water can bias diffusion measurements. The bi-tensor diffusion model was introduced to quantify the contribution of free-water and eliminates its bias on estimations of tissue microstructure. Here, we test the hypothesis that free-water is elevated in the substantia nigra for Parkinson’s disease compared with controls. This hypothesis was tested between large cohorts of Parkinson’s disease and control participants in a single-site study, and validated against a multi-site study using multiple scanners. The fractional volume of free-water was increased in the posterior region of the substantia nigra in Parkinson’s disease compared with controls in both the single-site and multi-site studies. We did not observe changes in either cohort for free-water corrected fractional anisotropy or free-water corrected mean diffusivity. Our findings provide new evidence that the free-water index reflects alteration of the substantia nigra in Parkinson’s disease, and this was evidenced across both single-site and multi-site cohorts. PMID:25467638

  9. High-Accuracy Quartic Force Field Calculations for the Spectroscopic Constants and Vibrational Frequencies of 1(exp 1)A' l-C3H(-): A Possible Link to Lines Observed in the Horsehead Nebula PDR

    NASA Technical Reports Server (NTRS)

    Fortenberry, Ryan C.; Huang, Xinchuan; Crawford, T. Daniel; Lee, Timothy J.

    2013-01-01

    It has been shown that rotational lines observed in the Horsehead nebula photon-dominated-region (PDR) are probably not caused by l-C3H+, as was originally suggested. In the search for viable alternative candidate carriers, quartic force fields are employed here to provide highly accurate rotational constants, as well as fundamental vibrational frequencies, for another candidate carrier: 1 (sup 1)A' C3H(-). The ab initio computed spectroscopic constants provided in this work are, compared to those necessary to define the observed lines, as accurate as the computed spectroscopic constants for many of the known interstellar anions. Additionally, the computed D-eff for C3H(-) is three times closer to the D deduced from the observed Horsehead nebula lines relative to l-C3H(+). As a result, 1 (sup 1)A' C3H(-). is a more viable candidate for these observed rotational transitions and would be the seventh confirmed interstellar anion detected within the past decade and the first C(sub n)H(-) molecular anion with an odd n.

  10. A modular class of multisite monthly rainfall generators for water resource management and impact studies

    NASA Astrophysics Data System (ADS)

    Serinaldi, Francesco; Kilsby, Chris G.

    2012-09-01

    SummaryThis study introduces a class of stochastic multisite monthly rainfall generators devised for application in water resources management problems, such as the sensitivity analysis of droughts and extreme rainfall scenarios under external climatic and non-climatic forcing mechanisms. The modelling framework relies on three elements: (1) a classical deseasonalisation scheme based on log-transformed observations, (2) the nonparametric bootstrap resampling approach and (3) parametric Generalized Additive Models for Location, Scale and Shape (GAMLSS). As the bootstrap and GAMLSS modules are alternative techniques for simulating each month, the free choice between them makes the structure of the model modular and flexible, so that it can be easily adapted to different climatic conditions, and can be customized based on the specific water resource problem. The model was set up and calibrated to simulate monthly rainfall from six locations in England and Wales to produce a suitable input for drought analysis. The results of the case study point out that the model can capture several characteristics of the rainfall series. In particular, it enables the simulation of low and high rainfall scenarios more extreme than those observed as well as the reproduction of the distribution of the annual accumulated rainfall, and of the relationship between the rainfall and circulation indices such as North Atlantic Oscillation (NAO) and Sea Surface Temperature (SST), thus making the framework well-suited for sensitivity analysis under alternative climate scenarios and additional forcing variables.

  11. A DVD Spectroscope: A Simple, High-Resolution Classroom Spectroscope

    ERIC Educational Resources Information Center

    Wakabayashi, Fumitaka; Hamada, Kiyohito

    2006-01-01

    Digital versatile disks (DVDs) have successfully made up an inexpensive but high-resolution spectroscope suitable for classroom experiments that can easily be made with common material and gives clear and fine spectra of various light sources and colored material. The observed spectra can be photographed with a digital camera, and such images can…

  12. Four-dimensional multi-site photolysis of caged neurotransmitters

    PubMed Central

    Go, Mary Ann; To, Minh-Son; Stricker, Christian; Redman, Stephen; Bachor, Hans-A.; Stuart, Greg J.; Daria, Vincent R.

    2013-01-01

    Neurons receive thousands of synaptic inputs that are distributed in space and time. The systematic study of how neurons process these inputs requires a technique to stimulate multiple yet highly targeted points of interest along the neuron's dendritic tree. Three-dimensional multi-focal patterns produced via holographic projection combined with two-photon photolysis of caged compounds can provide for highly localized release of neurotransmitters within each diffraction-limited focus, and in this way emulate simultaneous synaptic inputs to the neuron. However, this technique so far cannot achieve time-dependent stimulation patterns due to fundamental limitations of the hologram-encoding device and other factors that affect the consistency of controlled synaptic stimulation. Here, we report an advanced technique that enables the design and application of arbitrary spatio-temporal photostimulation patterns that resemble physiological synaptic inputs. By combining holographic projection with a programmable high-speed light-switching array, we have overcome temporal limitations with holographic projection, allowing us to mimic distributed activation of synaptic inputs leading to action potential generation. Our experiments uniquely demonstrate multi-site two-photon glutamate uncaging in three dimensions with submillisecond temporal resolution. Implementing this approach opens up new prospects for studying neuronal synaptic integration in four dimensions. PMID:24348330

  13. Complementary Therapies for Children Undergoing Stem Cell Transplant: Report of A Multisite Trial

    PubMed Central

    Phipps, Sean; Barrera, Maru; Vannatta, Kathryn; Xiong, Xiaoping; Doyle, John J; Alderfer, Melissa A.

    2010-01-01

    Background Children undergoing stem cell transplant (SCT) experience high levels of somatic distress and mood disturbance. This trial evaluated the efficacy of complementary therapies (massage, humor therapy, relaxation/imagery) for reducing distress associated with pediatric SCT. Methods Across 4 sites, 178 pediatric patients scheduled to undergo SCT were randomized to a child-targeted intervention involving massage and humor therapy (HPI-C), the identical child intervention plus a parent intervention involving massage and relaxation/imagery (HPI-CP) or standard care (SC). Randomization was stratified by site, age, and type of transplant. The interventions began at admission and continued through SCT week +3. Primary outcomes included patient and parent reports of somatic distress and mood disturbance obtained weekly from admission through week +6 using the BASES scales. Secondary outcomes included length of hospitalization, time to engraftment, and usage of narcotic analgesic and antiemetic medications. Results A mixed model approach was used to assess longitudinal trends of patient and parent-report outcomes and test differences between groups on these measures. Significant changes across time were observed on all patient and parent-report outcomes. However, no significant differences between treatment arms were found on the primary outcomes. Similarly, no signficant between group differences were noted on any of the medical variables as secondary outcomes. Conclusions Results of this multi-site trial failed to document significant benefits of complementary interventions in the pediatric SCT setting. PMID:20626016

  14. Multisite, multimodal neuroimaging of chronic urological pelvic pain: Methodology of the MAPP Research Network.

    PubMed

    Alger, Jeffry R; Ellingson, Benjamin M; Ashe-McNalley, Cody; Woodworth, Davis C; Labus, Jennifer S; Farmer, Melissa; Huang, Lejian; Apkarian, A Vania; Johnson, Kevin A; Mackey, Sean C; Ness, Timothy J; Deutsch, Georg; Harris, Richard E; Clauw, Daniel J; Glover, Gary H; Parrish, Todd B; Hollander, Jan den; Kusek, John W; Mullins, Chris; Mayer, Emeran A

    2016-01-01

    The Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network is an ongoing multi-center collaborative research group established to conduct integrated studies in participants with urologic chronic pelvic pain syndrome (UCPPS). The goal of these investigations is to provide new insights into the etiology, natural history, clinical, demographic and behavioral characteristics, search for new and evaluate candidate biomarkers, systematically test for contributions of infectious agents to symptoms, and conduct animal studies to understand underlying mechanisms for UCPPS. Study participants were enrolled in a one-year observational study and evaluated through a multisite, collaborative neuroimaging study to evaluate the association between UCPPS and brain structure and function. 3D T1-weighted structural images, resting-state fMRI, and high angular resolution diffusion MRI were acquired in five participating MAPP Network sites using 8 separate MRI hardware and software configurations. We describe the neuroimaging methods and procedures used to scan participants, the challenges encountered in obtaining data from multiple sites with different equipment/software, and our efforts to minimize site-to-site variation. PMID:27408791

  15. Gattini: a multisite campaign for the measurement of sky brightness in Antarctica

    NASA Astrophysics Data System (ADS)

    Moore, Anna; Allen, Graham; Aristidi, Eric; Ashley, Michael; Bedding, Tim; Beichman, Chas; Briguglio, Runa; Busso, Maurizio; Candidi, Maurizio; Ciardi, David; Cui, Xiangqun; Cutispoto, Giuseppe; Distefano, Elisa; Espy, Patrick; Everett, Jon; Feng, Longlong; Hu, Jingyao; Jiang, Zhaoji; Kenyon, Suzanne; Kulesa, Craig; Lawrence, Jon; Le Roux, Brice; Leslie, Tim; Li, Yuangshen; Luong-Van, Daniel; Phillips, Andre; Qin, Weijian; Ragazzoni, Roberto; Riddle, Reed; Sabbatini, Lucia; Salinari, Piero; Saunders, Will; Shang, Zhaohui; Stello, Dennis; Storey, John; Sun, Bo; Suntzeff, Nicolas; Taylor, Melinda; Tosti, Gino; Tothill, Nick; Travouillon, Tony; Van Belle, Gerard; Von Braun, Kaspar; Wang, Lifan; Yan, Jun; Yang, Huigen; Yuan, Xiangyan; Zhu, Zhenxi; Zhou, Xu

    2008-07-01

    We present the Gattini project: a multisite campaign to measure the optical sky properties above the two high altitude Antarctic astronomical sites of Dome C and Dome A. The Gattini-DomeC project, part of the IRAIT site testing campaign and ongoing since January 2006, consists of two cameras for the measurement of optical sky brightness, large area cloud cover and auroral detection above the DomeC site, home of the French-Italian Concordia station. The cameras are transit in nature and are virtually identical except for the nature of the lenses. The cameras have operated successfully throughout the past two Antarctic winter seasons and here we present the first results obtained from the returned 2006 dataset. The Gattini-DomeA project will place a similar site testing facility at the highest point on the Antarctic plateau, Dome A, with observations commencing in 2008. The project forms a small part of a much larger venture coordinated by the Polar Research Institute of China as part of the International Polar Year whereby an automated site testing facility called PLATO will be traversed into the DomeA site. The status of this exciting and ambitious project with regards to the Gattini-DomeA cameras will be presented.

  16. Coping Skills Among Adolescent Suicide Attempters: Results of a Multisite Study

    PubMed Central

    Mirkovic, Bojan; Labelle, Réal; Guilé, Jean-Marc; Belloncle, Vincent; Bodeau, Nicolas; Knafo, Alexandra; Condat, Agnès; Bapt-Cazalets, Nathalie; Marguet, Christophe; Breton, Jean-Jacques; Cohen, David; Gérardin, Priscille

    2015-01-01

    Objectives: A multisite study was undertaken to advance our understanding of how coping skills, depression, and suicidal ideation are related among adolescents who attempt suicide. Two hypotheses were postulated: productive coping and nonproductive coping would be associated, respectively, with lower and higher depression scores when age, sex, and stressful life events (SLEs) were controlled; and productive coping and nonproductive coping would be associated, respectively, with the presence and absence of suicidal ideation when age, sex, and SLEs were controlled. Methods: Participants were 167 adolescents (13 to 17 years of age) hospitalized for attempting suicide in 5 pediatric departments across France. Four instruments were administered: the Kiddie Schedule for Affective Disorders and Schizophrenia—Present and Lifetime Version, the Adolescent Coping Scale, the Life Events Questionnaire, and the Columbia-Suicide Severity Rating Scale. Descriptive analyses and univariate and multiple regression models were completed. Results: Both hypotheses were confirmed. Focus on the positive emerged as a significant variable in both models; depression emerged as a significant variable in the suicidal ideation model. The only sex difference observed was that girls made greater use of wishful thinking and seek social support. Conclusions: These findings suggest that coping skills are important mechanisms through which depression and suicidal ideation are maintained after attempting suicide. In intervening with adolescents who have attempted suicide, it may be useful to emphasize cognitive work geared to looking on the bright side, positive thinking, and fighting depression. PMID:25886670

  17. Spectroscopic survey of LAMOST

    NASA Astrophysics Data System (ADS)

    Zhao, Yongheng

    2014-07-01

    LAMOST is a special reflecting Schmidt telescope. LAMOST breaks through the bottleneck of the large scale spectroscopic survey observation with both large aperture (effective aperture of 3.6 - 4.9m) and wide field of view (5 degrees). It is an innovative active reflecting Schmidt configuration achieved by changing mirror surface continuously to achieve a series different reflecting Schmidt system in different moments. By using the parallel controllable fiber positioning technique, the focal surface of 1.75 meters in diameter accommodates 4000 optical fibers. Also, LAMOST has 16 spectrographs with 32 CCD cameras. LAMOST is the telescope of the highest spectrum acquiring rate. As a national large scientific project, LAMOST project was proposed formally in 1996. The construction was started in 2001 and completed in 2008. After commission period, LAMOST pilot survey was started in October 2011 and spectroscopic survey began in September 2012. From October 2011 to June 2013, LAMOST has obtained more than 2 million spectra of celestial objects. There are 1.7 million spectra of stars, in which the stellar parameters (effective temperature, surface gravity, metalicitiy and radial velocity) of more than 1 million stars was obtained. In the first period of spectroscopic survey of LAMOST, 5 million of stellar spectra will be obtained and will make substantial contribution to the study of the stellar astrophysics and the structure of the Galaxy, such as the spheroid substructure of the Galaxy, the galactic gravitational potential and the distribution of the dark matter in the Galaxy, the extremely metal poor stars and hypervelocity stars, the 3D extinction in the Galaxy, the structure of thin and thick disks of the Galaxy, and so on.

  18. How Institutional and University Counselor Policies Effectively Respond to Victims of Cyber Violent Acts: A Multisite Case Study

    ERIC Educational Resources Information Center

    Richards, Gretchen M.

    2012-01-01

    This multisite case study examined how institutional and university counselor policies effectively respond to cyber violent acts. Stake's (2006) multisite case study methodology was used to identify seven themes from current literature. Two sites with four participants were selected. The participants included two counseling directors and the…

  19. Middle-Eastern plant communities tolerate 9 years of drought in a multi-site climate manipulation experiment

    PubMed Central

    Tielbörger, Katja; Bilton, Mark C.; Metz, Johannes; Kigel, Jaime; Holzapfel, Claus; Lebrija-Trejos, Edwin; Konsens, Irit; Parag, Hadas A.; Sternberg, Marcelo

    2014-01-01

    For evaluating climate change impacts on biodiversity, extensive experiments are urgently needed to complement popular non-mechanistic models which map future ecosystem properties onto their current climatic niche. Here, we experimentally test the main prediction of these models by means of a novel multi-site approach. We implement rainfall manipulations—irrigation and drought—to dryland plant communities situated along a steep climatic gradient in a global biodiversity hotspot containing many wild progenitors of crops. Despite the large extent of our study, spanning nine plant generations and many species, very few differences between treatments were observed in the vegetation response variables: biomass, species composition, species richness and density. The lack of a clear drought effect challenges studies classifying dryland ecosystems as most vulnerable to global change. We attribute this resistance to the tremendous temporal and spatial heterogeneity under which the plants have evolved, concluding that this should be accounted for when predicting future biodiversity change. PMID:25283495

  20. Ethics Review for a Multi-Site Project Involving Tribal Nations in the Northern Plains.

    PubMed

    Angal, Jyoti; Petersen, Julie M; Tobacco, Deborah; Elliott, Amy J

    2016-04-01

    Increasingly, Tribal Nations are forming ethics review panels, which function separately from institutional review boards (IRBs). The emergence of strong community representation coincides with a widespread effort supported by the U.S. Department of Health & Human Services and other federal agencies to establish a single IRB for all multi-site research. This article underscores the value of a tribal ethics review board and describes the tribal oversight for the Safe Passage Study-a multi-site, community-based project in the Northern Plains. Our experience demonstrates the benefits of tribal ethics review and makes a strong argument for including tribal oversight in future regulatory guidance for multi-site, community-based research. PMID:26928897

  1. Spectroscopic survey of LAMOST

    NASA Astrophysics Data System (ADS)

    Zhao, Yongheng

    2015-08-01

    LAMOST is a special reflecting Schmidt telescope. LAMOST breaks through the bottleneck of the large scale spectroscopic survey observation with both large aperture (effective aperture of 3.6 - 4.9m) and wide field of view (5 degrees). It is an innovative active reflecting Schmidt configuration achieved by changing mirror surface continuously to achieve a series different reflecting Schmidt system in different moments. By using the parallel controllable fiber positioning technique, the focal surface of 1.75 meters in diameter accommodates 4000 optical fibers. Also, LAMOST has 16 spectrographs with 32 CCD cameras. LAMOST is the telescope of the highest spectrum acquiring rate.In the spectroscopic survey of LAMOST from October 2011 to June 2014, LAMOST has obtained more than 4.13 million spectra of celestial objects. There are 3.27 million spectra of stars, in which the stellar parameters of 2.16 million stars were obtained.In the five-year regular survey upto 2017, LAMOST will obtaine 5 million stellar spectra, which would make substantial contribution to the study of the stellar astrophysics and the structure of the Galaxy, such as the spheroid substructure of the Galaxy, the galactic gravitational potential and the distribution of the dark matter in the Galaxy, the extremely metal poor stars and hypervelocity stars, the 3D extinction in the Galaxy, the structure of thin and thick disks of the Galaxy, and so on.

  2. HIGH-ACCURACY QUARTIC FORCE FIELD CALCULATIONS FOR THE SPECTROSCOPIC CONSTANTS AND VIBRATIONAL FREQUENCIES OF 1{sup 1} A' l-C{sub 3}H{sup -}: A POSSIBLE LINK TO LINES OBSERVED IN THE HORSEHEAD NEBULA PHOTODISSOCIATION REGION

    SciTech Connect

    Fortenberry, Ryan C.; Lee, Timothy J.; Huang, Xinchuan; Crawford, T. Daniel

    2013-07-20

    It has been shown that rotational lines observed in the Horsehead nebula photodissociation region (PDR) are probably not caused by l-C{sub 3}H{sup +}, as was originally suggested. In the search for viable alternative candidate carriers, quartic force fields are employed here to provide highly accurate rotational constants, as well as fundamental vibrational frequencies, for another candidate carrier: 1 {sup 1} A' C{sub 3}H{sup -}. The ab initio computed spectroscopic constants provided in this work are, compared to those necessary to define the observed lines, as accurate as the computed spectroscopic constants for many of the known interstellar anions. Additionally, the computed D{sub eff} for C{sub 3}H{sup -} is three times closer to the D deduced from the observed Horsehead nebula lines relative to l-C{sub 3}H{sup +}. As a result, 1 {sup 1} A' C{sub 3}H{sup -} is a more viable candidate for these observed rotational transitions. It has been previously proposed that at least C{sub 6}H{sup -} may be present in the Horsehead nebular PDR formed by way of radiative attachment through its dipole-bound excited state. C{sub 3}H{sup -} could form in a similar way through its dipole-bound state, but its valence excited state increases the number of relaxation pathways possible to reach the ground electronic state. In turn, the rate of formation for C{sub 3}H{sup -} could be greater than the rate of its destruction. C{sub 3}H{sup -} would be the seventh confirmed interstellar anion detected within the past decade and the first C{sub n}H{sup -} molecular anion with an odd n.

  3. High-accuracy Quartic Force Field Calculations for the Spectroscopic Constants and Vibrational Frequencies of 11 A' l-C3H-: A Possible Link to Lines Observed in the Horsehead Nebula Photodissociation Region

    NASA Astrophysics Data System (ADS)

    Fortenberry, Ryan C.; Huang, Xinchuan; Crawford, T. Daniel; Lee, Timothy J.

    2013-07-01

    It has been shown that rotational lines observed in the Horsehead nebula photodissociation region (PDR) are probably not caused by l-C3H+, as was originally suggested. In the search for viable alternative candidate carriers, quartic force fields are employed here to provide highly accurate rotational constants, as well as fundamental vibrational frequencies, for another candidate carrier: 1 1 A' C3H-. The ab initio computed spectroscopic constants provided in this work are, compared to those necessary to define the observed lines, as accurate as the computed spectroscopic constants for many of the known interstellar anions. Additionally, the computed D eff for C3H- is three times closer to the D deduced from the observed Horsehead nebula lines relative to l-C3H+. As a result, 1 1 A' C3H- is a more viable candidate for these observed rotational transitions. It has been previously proposed that at least C6H- may be present in the Horsehead nebular PDR formed by way of radiative attachment through its dipole-bound excited state. C3H- could form in a similar way through its dipole-bound state, but its valence excited state increases the number of relaxation pathways possible to reach the ground electronic state. In turn, the rate of formation for C3H- could be greater than the rate of its destruction. C3H- would be the seventh confirmed interstellar anion detected within the past decade and the first C n H- molecular anion with an odd n.

  4. THE BOLOCAM GALACTIC PLANE SURVEY. X. A COMPLETE SPECTROSCOPIC CATALOG OF DENSE MOLECULAR GAS OBSERVED TOWARD 1.1 mm DUST CONTINUUM SOURCES WITH 7.°5 ≤ l ≤ 194°

    SciTech Connect

    Shirley, Yancy L.; Svoboda, Brian; Ellsworth-Bowers, Timothy P.; Schlingman, Wayne M.; Ginsburg, Adam; Battersby, Cara; Stringfellow, Guy; Glenn, Jason; Bally, John; Rosolowsky, Erik; Gerner, Thomas; Mairs, Steven; Dunham, Miranda K.

    2013-11-01

    The Bolocam Galactic Plane Survey (BGPS) is a 1.1 mm continuum survey of dense clumps of dust throughout the Galaxy covering 170 deg{sup 2}. We present spectroscopic observations using the Heinrich Hertz Submillimeter Telescope of the dense gas tracers, HCO{sup +} and N{sub 2}H{sup +} 3-2, for all 6194 sources in the BGPS v1.0.1 catalog between 7.°5 ≤ l ≤ 194°. This is the largest targeted spectroscopic survey of dense molecular gas in the Milky Way to date. We find unique velocities for 3126 (50.5%) of the BGPS v1.0.1 sources observed. Strong N{sub 2}H{sup +} 3-2 emission (T {sub mb} > 0.5 K) without HCO{sup +} 3-2 emission does not occur in this catalog. We characterize the properties of the dense molecular gas emission toward the entire sample. HCO{sup +} is very sub-thermally populated and the 3-2 transitions are optically thick toward most BGPS clumps. The median observed line width is 3.3 km s{sup –1} consistent with supersonic turbulence within BGPS clumps. We find strong correlations between dense molecular gas integrated intensities and 1.1 mm peak flux and the gas kinetic temperature derived from previously published NH{sub 3} observations. These intensity correlations are driven by the sensitivity of the 3-2 transitions to excitation conditions rather than by variations in molecular column density or abundance. We identify a subset of 113 sources with stronger N{sub 2}H{sup +} than HCO{sup +} integrated intensity, but we find no correlations between the N{sub 2}H{sup +}/HCO{sup +} ratio and 1.1 mm continuum flux density, gas kinetic temperature, or line width. Self-absorbed profiles are rare (1.3%)

  5. Patterns of multisite pain and associations with risk factors

    PubMed Central

    Coggon, David; Ntani, Georgia; Palmer, Keith T.; Felli, Vanda E.; Harari, Raul; Barrero, Lope H.; Felknor, Sarah A.; Gimeno, David; Cattrell, Anna; Vargas-Prada, Sergio; Bonzini, Matteo; Solidaki, Eleni; Merisalu, Eda; Habib, Rima R.; Sadeghian, Farideh; Masood Kadir, M.; Warnakulasuriya, Sudath S.P.; Matsudaira, Ko; Nyantumbu, Busisiwe; Sim, Malcolm R.; Harcombe, Helen; Cox, Ken; Marziale, Maria H.; Sarquis, Leila M.; Harari, Florencia; Freire, Rocio; Harari, Natalia; Monroy, Magda V.; Quintana, Leonardo A.; Rojas, Marianela; Salazar Vega, Eduardo J.; Harris, E. Clare; Serra, Consol; Martinez, J. Miguel; Delclos, George; Benavides, Fernando G.; Carugno, Michele; Ferrario, Marco M.; Pesatori, Angela C.; Chatzi, Leda; Bitsios, Panos; Kogevinas, Manolis; Oha, Kristel; Sirk, Tuuli; Sadeghian, Ali; Peiris-John, Roshini J.; Sathiakumar, Nalini; Wickremasinghe, A. Rajitha; Yoshimura, Noriko; Kelsall, Helen L.; Hoe, Victor C.W; Urquhart, Donna M.; Derrett, Sarah; McBride, David; Herbison, Peter; Gray, Andrew

    2013-01-01

    To explore definitions for multisite pain, and compare associations with risk factors for different patterns of musculoskeletal pain, we analysed cross-sectional data from the Cultural and Psychosocial Influences on Disability (CUPID) study. The study sample comprised 12,410 adults aged 20–59 years from 47 occupational groups in 18 countries. A standardised questionnaire was used to collect information about pain in the past month at each of 10 anatomical sites, and about potential risk factors. Associations with pain outcomes were assessed by Poisson regression, and characterised by prevalence rate ratios (PRRs). Extensive pain, affecting 6–10 anatomical sites, was reported much more frequently than would be expected if the occurrence of pain at each site were independent (674 participants vs 41.9 expected). In comparison with pain involving only 1–3 sites, it showed much stronger associations (relative to no pain) with risk factors such as female sex (PRR 1.6 vs 1.1), older age (PRR 2.6 vs 1.1), somatising tendency (PRR 4.6 vs 1.3), and exposure to multiple physically stressing occupational activities (PRR 5.0 vs 1.4). After adjustment for number of sites with pain, these risk factors showed no additional association with a distribution of pain that was widespread according to the frequently used American College of Rheumatology criteria. Our analysis supports the classification of pain at multiple anatomical sites simply by the number of sites affected, and suggests that extensive pain differs importantly in its associations with risk factors from pain that is limited to only a small number of anatomical sites. PMID:23727463

  6. Implementation and validation of a Wilks-type multi-site daily precipitation generator over a typical Alpine river catchment

    NASA Astrophysics Data System (ADS)

    Keller, D. E.; Fischer, A. M.; Frei, C.; Liniger, M. A.; Appenzeller, C.; Knutti, R.

    2015-05-01

    Many climate impact assessments require high-resolution precipitation time series that have a spatio-temporal correlation structure consistent with observations, for simulating either current or future climate conditions. In this respect, weather generators (WGs) designed and calibrated for multiple sites are an appealing statistical downscaling technique to stochastically simulate multiple realisations of possible future time series consistent with the local precipitation characteristics and their expected future changes. In this study, we present the implementation and validation of a multi-site daily precipitation generator re-built after the methodology described in Wilks (1998). The generator consists of several Richardson-type WGs run with spatially correlated random number streams. This study aims at investigating the capabilities, the added value and the limitations of the precipitation generator for a typical Alpine river catchment in the Swiss Alpine region under current climate. The calibrated multi-site WG is skilful at individual sites in representing the annual cycle of the precipitation statistics, such as mean wet day frequency and intensity as well as monthly precipitation sums. It reproduces realistically the multi-day statistics such as the frequencies of dry and wet spell lengths and precipitation sums over consecutive wet days. Substantial added value is demonstrated in simulating daily areal precipitation sums in comparison to multiple WGs that lack the spatial dependency in the stochastic process. Limitations are seen in reproducing daily and multi-day extreme precipitation sums, observed variability from year to year and in reproducing long dry spell lengths. Given the performance of the presented generator, we conclude that it is a useful tool to generate precipitation series consistent with the mean climatic aspects and likely helpful to be used as a downscaling technique for climate change scenarios.

  7. Spectroscopic Classifications of Optical Transients with SOAR

    NASA Astrophysics Data System (ADS)

    Hounsell, R. A.; Miller, J. A.; Pan, Y.-C.; Foley, R. J.; Jha, S. W.; Rest, A.; Scolnic, D.; Smith, K. W.; Wright, D.; Smartt, S. J.; Huber, M.; Chambers, K. C.; Flewelling, H.; Willman, M.; Primak, N.; Schultz, A.; Gibson, B.; Magnier, E.; Waters, C.; Tonry, J.; Wainscoat, R. J.

    2016-06-01

    We report the following classifications of optical transients from spectroscopic observations with the Goodman spectrograph on the SOAR 4-m telescope. Targets were supplied by the Pan-STARRS Survey for Transients (PSST).

  8. Medication Errors in the Home: A Multisite Study of Children With Cancer

    PubMed Central

    Roblin, Douglas W.; Weingart, Saul N.; Houlahan, Kathleen E.; Degar, Barbara; Billett, Amy; Keuker, Christopher; Biggins, Colleen; Li, Justin; Wasilewski, Karen; Mazor, Kathleen M.

    2013-01-01

    OBJECTIVE: As home medication use increases, medications previously managed by nurses are now managed by patients and their families. Our objective was to describe the types of errors occurring in the home medication management of children with cancer. METHODS: In a prospective observational study at 3 pediatric oncology clinics in the northeastern and southeastern United States, patients undergoing chemotherapy and their parents were recruited from November 2007 through April 2011. We reviewed medical records and checked prescription doses. A trained nurse visited the home, reviewed medication bottles, and observed administration. Two physicians independently made judgments regarding whether an error occurred and its severity. Overall rates of errors were weighted to account for clustering within sites. RESULTS: We reviewed 963 medications and observed 242 medication administrations in the homes of 92 patients. We found 72 medication errors. Four errors led to significant patient injury. An additional 40 errors had potential for injury: 2 were life-threatening, 13 were serious, and 25 were significant. Error rates varied between study sites (40–121 errors per 100 patients); the weighted overall rate was 70.2 errors per 100 patients (95% confidence interval [CI]: 58.9–81.6). The weighted rate of errors with injury was 3.6 (95% CI: 1.7–5.5) per 100 patients and with potential to injure the patient was 36.3 (95% CI: 29.3–43.3) per 100 patients. Nonchemotherapy medications were more often involved in an error than chemotherapy. CONCLUSIONS: Medication errors were common in this multisite study of outpatient pediatric cancer care. Rates of preventable medication-related injuries in this outpatient population were comparable or higher than those found in studies of hospitalized patients. PMID:23629608

  9. The Ionization of the Local Interstellar Medium as Revealed by Far Ultraviolet Spectroscopic Explorer Observations of N, O, and AR toward White Dwarf Stars

    NASA Astrophysics Data System (ADS)

    Jenkins, E. B.; Oegerle, W. R.; Gry, C.; Vallerga, J.; Sembach, K. R.; Shelton, R. L.; Ferlet, R.; Vidal-Madjar, A.; York, D. G.; Linsky, J. L.; Roth, K. C.; Dupree, A. K.; Edelstein, J.

    2000-07-01

    Far Ultraviolet Spectroscopic Explorer spectra of the white dwarf stars G191-B2B, GD 394, WD 2211-495, and WD 2331-475 cover the absorption features out of the ground electronic states of N I, N II, N III, O I, and Ar I in the far-ultraviolet, providing new insights on the origin of the partial ionization of the local interstellar medium (LISM) and, for the case of G191-B2B, the interstellar cloud that immediately surrounds the solar system. Toward these targets the interstellar abundances of Ar I, and sometimes N I, are significantly below their cosmic abundances relative to H I. In the diffuse interstellar medium, these elements are not likely to be depleted onto dust grains. Generally, we expect that Ar should be more strongly ionized than H (and also O and N, whose ionizations are coupled to that of H via charge-exchange reactions) because the cross section for the photoionization of Ar I is very high. Our finding that Ar I/H I is low may help to explain the surprisingly high ionization of He in the LISM found by other investigators. Our result favors the interpretation that the ionization of the local medium is maintained by a strong extreme-ultraviolet flux from nearby stars and hot gases, rather than an incomplete recovery from a past, more highly ionized condition. Based on data obtained for the Guaranteed Time Team by the NASA-CNES-CSA FUSE mission operated by Johns Hopkins University. Financial support to US participants has been provided by NASA contract NAS5-32985.

  10. Scattered light in the echelle modes of the Goddard High Resolution Spectrograph aboard the Hubble Space Telescope. II - Analysis of in-flight spectroscopic observations

    NASA Technical Reports Server (NTRS)

    Cardelli, Jason A.; Ebbets, Dennis C.; Savage, Blair D.

    1993-01-01

    We report on an analysis of observations made with the GHRS aboard the HST for the purpose of calibrating the effects of scattered light. The data were obtained during the first 2 years of flight operations as part of the Science Verification, Science Assessment Observations, and Guaranteed Time Observations programs. Both the general level of background light near the spectra and the filling-in of the cores of saturated interstellar absorption lines have been determined as functions of grating, order, wavelength, and aperture. The behavior is in accordance with our detailed analysis of prelaunch laboratory data and validates both the observing procedures and the data reduction developed on the basis of that experience. We present and discuss the use of a background (scattered light) removal algorithm designed to produce net spectra properly corrected for the effects of grating scattered light. The coefficients of the scattered light removal algorithm have been determined, and recommended numerical values are presented.

  11. A Multisite Psychotherapy and Medication Trial for Depressed Adolescents: Background and Benefits

    ERIC Educational Resources Information Center

    Kratochvil, Christopher J.; Simons, Anne; Vitiello, Benedetto; Walkup, John; Emslie, Graham; Rosenberg, David; March, John S.

    2005-01-01

    The Treatment for Adolescents With Depression Study (TADS) is an NIMH-supported multisite clinical trial that compares the effectiveness of a depression-specific cognitive behavioral therapy (CBT), medication management with fluoxetine (FLX), the combination of CBT and FLX (COMB), and medical management with pill placebo (PBO). TADS was…

  12. A Multisite Randomized Effectiveness Trial of Motivational Enhancement Therapy for Spanish-Speaking Substance Users

    ERIC Educational Resources Information Center

    Carroll, Kathleen M.; Martino, Steve; Ball, Samuel A.; Nich, Charla; Frankforter, Tami; Anez, Luis M.; Paris, Manuel; Suarez-Morales, Lourdes; Szapocznik, Jose; Miller, William R.; Rosa, Carmen; Matthews, Julie; Farentinos, Chris

    2009-01-01

    Hispanic individuals are underrepresented in clinical and research populations and are often excluded from clinical trials in the United States. Hence, there are few data on the effectiveness of most empirically validated therapies for Hispanic substance users. The authors conducted a multisite randomized trial comparing the effectiveness of 3…

  13. Site Matters: Multisite Randomized Trial of Motivational Enhancement Therapy in Community Drug Abuse Clinics

    ERIC Educational Resources Information Center

    Ball, Samuel A.; Martino, Steve; Nich, Charla; Frankforter, Tami L.; Van Horn, Deborah; Crits-Christoph, Paul; Woody, George E.; Obert, Jeanne L.; Farentinos, Christiane; Carroll, Kathleen M.

    2007-01-01

    The effectiveness of motivational enhancement therapy (MET) in comparison with counseling as usual (CAU) for increasing retention and reducing substance use was evaluated in a multisite randomized clinical trial. Participants were 461 outpatients treated by 31 therapists within 1 of 5 outpatient substance abuse programs. There were no retention…

  14. Intraclass Correlations for Three-Level Multi-Site Cluster-Randomized Trials of Science Achievement

    ERIC Educational Resources Information Center

    Westine, Carl D.

    2015-01-01

    A cluster-randomized trial (CRT) relies on random assignment of intact clusters to treatment conditions, such as classrooms or schools (Raudenbush & Bryk, 2002). One specific type of CRT, a multi-site CRT (MSCRT), is commonly employed in educational research and evaluation studies (Spybrook & Raudenbush, 2009; Spybrook, 2014; Bloom,…

  15. Statistical Analysis for Multisite Trials Using Instrumental Variables with Random Coefficients

    ERIC Educational Resources Information Center

    Raudenbush, Stephen W.; Reardon, Sean F.; Nomi, Takako

    2012-01-01

    Multisite trials can clarify the average impact of a new program and the heterogeneity of impacts across sites. Unfortunately, in many applications, compliance with treatment assignment is imperfect. For these applications, we propose an instrumental variable (IV) model with person-specific and site-specific random coefficients. Site-specific IV…

  16. Brief Treatments for Cannabis Dependence: Findings From a Randomized Multisite Trial

    ERIC Educational Resources Information Center

    Babor, Thomas F.

    2004-01-01

    This study evaluated the efficacy of 2 brief interventions for cannabis-dependent adults. A multisite randomized controlled trial compared cannabis use outcomes across 3 study conditions: (a) 2 sessions of motivational enhancement therapy (MET); (b) 9 sessions of multicomponent therapy that included MET, cognitive-behavioral therapy, and case…

  17. Learning about and from a Distribution of Program Impacts Using Multisite Trials

    ERIC Educational Resources Information Center

    Raudenbush, Stephen W.; Bloom, Howard S.

    2015-01-01

    The present article provides a synthesis of the conceptual and statistical issues involved in using multisite randomized trials to learn about and from a distribution of heterogeneous program impacts across individuals and/or program sites. Learning "about" such a distribution involves estimating its mean value, detecting and quantifying…

  18. The 2002 Multisite Conference on the Future of School Psychology: Next Steps

    ERIC Educational Resources Information Center

    Dawson, Margaret; Cummings, Jack A.; Harrison, Patti L.; Short, Rick J.; Gorin, Susan; Palomares, Ron

    2003-01-01

    Eleven broad themes emerged from the 2002 multisite conference on the Future of School Psychology. After the conference, strategies developed by the participants were clustered into the following domains: (a) advocacy and public policy; (b) research and knowledge base; (c) collaboration and communication; (d) practice; (e) preservice training; and…

  19. The 2002 Multisite Conference on the Future of School Psychology: Next Steps

    ERIC Educational Resources Information Center

    Dawson, Margaret; Cummings, Jack A.; Harrison, Patti L.; Short, Rick J.; Gorin, Susan; Palomares, Ron

    2004-01-01

    Eleven broad themes emerged from the 2002 multisite conference on the Future of School Psychology. After the conference, strategies developed by the participants were clustered into the following domains: (a) advocacy and public policy; (b) research and knowledge base; (c) collaboration and communication; (d) practice; (e) preservice training; and…

  20. Childhood Traumatic Grief: A Multi-Site Empirical Examination of the Construct and Its Correlates

    ERIC Educational Resources Information Center

    Brown, Elissa J.; Amaya-Jackson, Lisa; Cohen, Judith; Handel, Stephanie; De Bocanegra, Heike Thiel; Zatta, Eileen; Goodman, Robin F.; Mannarino, Anthony

    2008-01-01

    This study evaluated the construct of childhood traumatic grief (CTG) and its correlates through a multi-site assessment of 132 bereaved children and adolescents. Youth completed a new measure of the characteristics, attributions, and reactions to exposure to death (CARED), as well as measures of CTG, posttraumatic stress disorder (PTSD),…

  1. Positive Family Intervention for Severe Challenging Behavior I: A Multisite Randomized Clinical Trial

    ERIC Educational Resources Information Center

    Durand, V. Mark; Hieneman, Meme; Clarke, Shelley; Wang, Mo; Rinaldi, Melissa L.

    2013-01-01

    The present study was a multisite randomized clinical trial assessing the effects of adding a cognitive-behavioral intervention to positive behavior support (PBS). Fifty-four families who met the criteria of (a) having a child with a developmental disability, (b) whose child displayed serious challenging behavior (e.g., aggression, self-injury,…

  2. The Validation of the Evaluation Involvement Scale for Use in Multisite Settings

    ERIC Educational Resources Information Center

    Toal, Stacie A.

    2009-01-01

    Evaluation researchers and practitioners acknowledge that involving stakeholders in the planning and implementation of an evaluation increases buy-in, understanding, and use. With the recent increase in multi-site evaluations of large federal programs, evaluators must think differently about how to encourage meaningful collaboration by…

  3. Documenting the Impact of Multisite Evaluations on the Science, Technology, Engineering, and Mathematics Field

    ERIC Educational Resources Information Center

    Roseland, Denise; Greenseid, Lija O.; Volkov, Boris B.; Lawrenz, Frances

    2011-01-01

    This chapter discusses the impact that four multisite National Science Foundation (NSF) evaluations had on the broader field of science, technology, engineering, and mathematics education and evaluation. Three approaches were used to investigate the broader impact of these evaluations on the field: (a) a citation analysis, (b) an on-line survey,…

  4. Toward Better Research on--and Thinking about--Evaluation Influence, Especially in Multisite Evaluations

    ERIC Educational Resources Information Center

    Mark, Melvin M.

    2011-01-01

    Evaluation is typically carried out with the intention of making a difference in the understandings and actions of stakeholders and decision makers. The author provides a general review of the concepts of evaluation "use," evaluation "influence," and "influence pathways," with connections to multisite evaluations. The study of evaluation influence…

  5. Parental Engagement in Home Visiting Programs--Findings from the Parents as Teachers Multisite Evaluation.

    ERIC Educational Resources Information Center

    Wagner, Mary; Spiker, Donna; Gerlach-Downie, Suzanne; Hernandez, Frances

    This report presents the findings of a reassessment of an ongoing, multi-site evaluation of the Parents as Teachers (PAT) home visiting program. The evaluation had, from its inception, included data collection and analyses regarding engagement; however, a reassessment of research questions driving the evaluation shifted engagement from a secondary…

  6. Power Calculations for Moderators in Multi-Site Cluster Randomized Trials

    ERIC Educational Resources Information Center

    Spybrook, Jessaca; Kelcey, Ben; Dong, Nianbo

    2016-01-01

    Cluster randomized trials (CRTs), or studies in which intact groups of individuals are randomly assigned to a condition, are becoming more common in evaluation studies of educational programs. A specific type of CRT in which clusters are randomly assigned to treatment within blocks or sites, known as multisite cluster randomized trials (MSCRTs),…

  7. Effects of atmospheric light scattering in validating spectroscopic space-based observations of carbon dioxide by ground-based FTS measurements

    NASA Astrophysics Data System (ADS)

    Oshchepkov, S.; Bril, A.; Yokota, T.; Morino, I.; Yoshida, Y.; Matsunaga, T.; Wunch, D.; Toon, G.; O'Dell, C.; Butz, A.; Boesch, H.; Eguchi, N.

    2012-04-01

    This work describes a validation study of the Greenhouse gases Observing SATellite (GOSAT) data processing using ground-based measurements from the Total Carbon Column Observing Network (TCCON) as the reference data for column-averaged dry air mole fractions of atmospheric carbon dioxide (XCO2) during 22 months from June 2009. First we focus on the validation of the path length probability density function (PPDF) method when processing the GOSAT observations. This method permits direct evaluation of the optical path modifications due to atmospheric light scattering whose impact is negligible on the ground-based TCCON measurements but could significantly affect the results of gas retrievals when observing the green house gases from space. We have found an effect from lengthening the optical path over Northern hemisphere stations essentially from June to September each year and from shortening the optical path for sun glint observations in the tropical regions. Removing these observations from the GOSAT dataset provided acceptable agreement in seasonal variability of carbon dioxide over each station as compared with TCCON measurements. A statistical comparison between GOSAT and TCCON coincident measurements of CO2 column abundance showed a correlation coefficient 0.8; a standard deviation of 2.15 ppmv, and a small negative bias of 0.4 ppmv over all 12 TCCON sites. Next PPDF-based data processing was compared with those derived by other algorithms including the official GOSAT data products from the National Institute for Environmental Studies (NIES, Japan) and NASA's Atmospheric CO2 Observations from Space (ACOS). We compare the XCO2 GOSAT-TCCON correlation diagrams and its seasonal variability for each algorithm with special emphasis on how the GOSAT single scans derived by each algorithm are distributed by the optical path modification.

  8. Predicting diffuse light-enhancement of GPP from plant functional traits: A multi-site synthesis

    NASA Astrophysics Data System (ADS)

    O'Halloran, T. L.; Barr, J. G.; Cook, B.; Goeckede, M.; Law, B. E.; Kueppers, L. M.; Riley, W. J.

    2013-12-01

    Diffuse light enhances canopy-scale photosynthesis because isotropic diffuse light penetrates deeper into the canopy, involves more leaf area in photosynthesis, and prevents the top of the canopy from becoming light saturated. However, the observational and modeling communities still have little understanding of how the 'Diffuse light Enhancement Effect' (DEE) varies across plant functional types or is constrained by factors such as nitrogen availability and plant structure. So far, variability in the strength of DEE across plant functional types (PFTs) remains poorly constrained, but canopy models indicate leaf area index (LAI) is a primary controller. While the very few existing multi-site, measurement-based syntheses of the DEE have provided valuable information on the variability of the DEE across a few plant functional types, no study has correlated measured metrics of DEE magnitude with direct measurements of canopy physical traits across a wide range of plant functional types. Here we report a new metric that is suitable for quantifying the DEE in both flux measurements and land surface models. We also present, for the first time, an examination of the relationship between the DEE metric and plant functional traits. Results from our 70+ site AmeriFlux and FLUXNET synthesis indicate that LAI is the strongest controller of the DEE across sites and PFTs, with less significant influences from foliar nitrogen, canopy height, and mean annual precipitation. Our results will enable direct evaluation and improvement of remote sensing algorithms and light use efficiency models (e.g. MODIS GPP), which to this point regard diffuse light fraction as a source of noise. Additionally, improving resolution of the DEE in prognostic land surface models, such as the Community Land Model (CLM), will greatly improve our ability to forecast future feedbacks to terrestrial carbon sequestration from changes in cloudiness and aerosol amount.

  9. Multisite Parent-Centered Risk Assessment to Reduce Pediatric Oral Chemotherapy Errors

    PubMed Central

    Walsh, Kathleen E.; Mazor, Kathleen M.; Roblin, Douglas; Biggins, Colleen; Wagner, Joann L.; Houlahan, Kathleen; Li, Justin W.; Keuker, Christopher; Wasilewski-Masker, Karen; Donovan, Jennifer; Kanaan, Abir; Weingart, Saul N.

    2013-01-01

    Purpose: Observational studies describe high rates of errors in home oral chemotherapy use in children. In hospitals, proactive risk assessment methods help front-line health care workers develop error prevention strategies. Our objective was to engage parents of children with cancer in a multisite study using proactive risk assessment methods to identify how errors occur at home and propose risk reduction strategies. Methods: We recruited parents from three outpatient pediatric oncology clinics in the northeast and southeast United States to participate in failure mode and effects analyses (FMEA). An FMEA is a systematic team-based proactive risk assessment approach in understanding ways a process can fail and develop prevention strategies. Steps included diagram the process, brainstorm and prioritize failure modes (places where things go wrong), and propose risk reduction strategies. We focused on home oral chemotherapy administration after a change in dose because prior studies identified this area as high risk. Results: Parent teams consisted of four parents at two of the sites and 10 at the third. Parents developed a 13-step process map, with two to 19 failure modes per step. The highest priority failure modes included miscommunication when receiving instructions from the clinician (caused by conflicting instructions or parent lapses) and unsafe chemotherapy handling at home. Recommended risk assessment strategies included novel uses of technology to improve parent access to information, clinicians, and other parents while at home. Conclusion: Parents of pediatric oncology patients readily participated in a proactive risk assessment method, identifying processes that pose a risk for medication errors involving home oral chemotherapy. PMID:23633976

  10. RMAWGEN: A software project for a daily Multi-Site Weather Generator with R

    NASA Astrophysics Data System (ADS)

    Cordano, E.; Eccel, E.

    2012-04-01

    The modeling in in climate change applications for agricultural or hydrological purposes often requires daily time-series of precipitation and temperature. This is the case of downscaled series from monthly or seasonal predictions of Global Climate Models (GCMs). This poster presents a software project, the R package RMAWGEN (R Multi-Sites Auto-regressive Weather GENerator), to generate daily temperature and precipitation time series in several sites by using the theory of vectorial auto-regressive models (VAR). The VAR model is used because it is able to maintain the temporal and spatial correlations among the several series. In particular, observed time series of daily maximum and minimum temperature and precipitation are used to calibrate the parameters of a VAR model (saved as "GPCAvarest2" or "varest2" classes, which inherit the "varest" S3 class defined in the package vars [Pfaff, 2008]). Therefore the VAR model, coupled with monthly mean weather variables downscaled by GCM predictions, allows to generate several stochastic daily scenarios. The structure of the package consists in functions that transform precipitation and temperature time series into Gaussian-distributed random variables through deseasonalization and Principal Component Analysis. Then a VAR model is calibrated on transformed time series. The time series generated by VAR are then inversely re-transformed into precipitation and/or temperature series. An application is included in the software package as an example; it is presented by using a dataset with daily weather time series recorded in 59 different sites of Trentino (Italy) and its neighborhoods for the period 1958-2007. The software is distributed as a Free Software with General Public License (GPL) and is available on CRAN website (http://cran.r-project.org/web/packages/RMAWGEN/index.html)

  11. The work of commissioning: a multisite case study of healthcare commissioning in England's NHS

    PubMed Central

    Shaw, Sara E; Smith, Judith A; Porter, Alison; Rosen, Rebecca; Mays, Nicholas

    2013-01-01

    Objective To examine the work of commissioning care for people with long-term conditions and the factors inhibiting or facilitating commissioners making service change. Design Multisite mixed methods case study research, combining qualitative analysis of interviews, documents and observation of meetings. Participants Primary care trust managers and clinicians, general practice-based commissioners, National Health Service trust and foundation trust senior managers and clinicians, voluntary sector and local government representatives. Setting Three ‘commissioning communities’ (areas covered by a primary care trust) in England, 2010–2012. Results Commissioning services for people with long-term conditions was a long drawn-out process involving a range of activities and partners. Only some of the activities undertaken by commissioners, such as assessment of local health needs, coordination of healthcare planning and service specification, appeared in the official ‘commissioning cycle’ promoted by the Department of Health. Commissioners undertook a significant range of additional activities focused on reviewing and redesigning services and providing support for implementation of new services. These activities often involved partnership working with providers and other stakeholders and appeared to be largely divorced from contracting and financial negotiations. At least for long-term condition services, the time and effort involved in such work appeared to be disproportionate to the anticipated or likely service gains. Commissioners adopting an incremental approach to service change in defined and manageable areas of work appeared to be more successful in terms of delivering planned changes in service delivery than those attempting to bring about wide-scale change across complex systems. Conclusions Commissioning for long-term condition services challenges the conventional distinction between commissioners and providers with a significant amount of work focused

  12. Single nanoparticle tracking spectroscopic microscope

    DOEpatents

    Yang, Haw; Cang, Hu; Xu, Cangshan; Wong, Chung M.

    2011-07-19

    A system that can maintain and track the position of a single nanoparticle in three dimensions for a prolonged period has been disclosed. The system allows for continuously imaging the particle to observe any interactions it may have. The system also enables the acquisition of real-time sequential spectroscopic information from the particle. The apparatus holds great promise in performing single molecule spectroscopy and imaging on a non-stationary target.

  13. Communication: Spectroscopic observation of the O-bonded T-shaped isomer of the CO-CO2 dimer and two of its intermolecular frequencies.

    PubMed

    Sheybani-Deloui, S; Barclay, A J; Michaelian, K H; McKellar, A R W; Moazzen-Ahmadi, N

    2015-09-28

    Infrared spectra in the carbon monoxide CO stretch region (≈2150 cm(-1)) are assigned to the previously unobserved O-bonded form of the CO2-CO dimer ("isomer 2"), which has a planar T-shaped structure like that of the previously observed C-bonded form ("isomer 1"), but with the CO rotated by 180°. The effective center of mass intermolecular distances are 3.58 Å for isomer 2 as compared to 3.91 Å for isomer 1. In addition to the fundamental band, two combination bands are observed for isomer 2, yielding values for two intermolecular vibrational modes: 14.19 cm(-1) for the in-plane CO bend and 22.68 cm(-1) for the out-of-plane bend. PMID:26428988

  14. Communication: Spectroscopic observation of the O-bonded T-shaped isomer of the CO-CO2 dimer and two of its intermolecular frequencies

    NASA Astrophysics Data System (ADS)

    Sheybani-Deloui, S.; Barclay, A. J.; Michaelian, K. H.; McKellar, A. R. W.; Moazzen-Ahmadi, N.

    2015-09-01

    Infrared spectra in the carbon monoxide CO stretch region (≈2150 cm-1) are assigned to the previously unobserved O-bonded form of the CO2-CO dimer ("isomer 2"), which has a planar T-shaped structure like that of the previously observed C-bonded form ("isomer 1"), but with the CO rotated by 180°. The effective center of mass intermolecular distances are 3.58 Å for isomer 2 as compared to 3.91 Å for isomer 1. In addition to the fundamental band, two combination bands are observed for isomer 2, yielding values for two intermolecular vibrational modes: 14.19 cm-1 for the in-plane CO bend and 22.68 cm-1 for the out-of-plane bend.

  15. Microwave and millimeter wave astrochemistry: Laboratory studies of transition metal-containing free radicals and spectroscopic observations of molecular interstellar environments

    NASA Astrophysics Data System (ADS)

    Adande, Gilles Rapotchombo

    Progress in our understanding of the chemical composition of the interstellar medium leans both on laboratory analyses of high resolution rotational spectra from molecules that may be present in these regions, and on radio astronomical observations of molecular tracers to constrain astrochemical models. Due to the thermodynamic conditions in outer space, some molecules likely to be found in interstellar regions in relevant abundances are open shell radicals. In a series of laboratory studies, the pure rotational spectra of the transition metal containing radicals sulfur species ScS, YS, VS and ZnSH were obtained for the first time. In addition to accurate and precise rest frequencies for these species, bonding characteristics were determined from fine and hyperfine molecular parameters. It was found that these sulfides have a higher degree of covalent bonding than their mostly ionic oxide counterparts. Isomers and isotope ratios are excellent diagnostic tools for a variety of astrochemical models. From radio observations of isotopes of nitrile species, the galactic gradient of 14N/15N was accurately established. A further study of this ratio in carbon rich asymptotic giant branch stars provided observational evidence for an unknown process in J type carbon stars, and highlighted the need to update stellar nucleosynthesis models. Proper radiative transfer modeling of the emission spectra of interstellar molecules can yield a wealth of information about the abundance and distribution of these species within the observed sources. To model the asymmetric emission of SO and SO2 in oxygen-rich supergiants, an in-house code was developed, and successfully applied to gain insight into circumstellar sulfur chemistry of VY Canis Majoris. It was concluded that current astrochemistry kinetic models, based on spherical symmetry assumptions, need to be revisited.

  16. Infrared spectroscopic observation of the stabilized intermediate complex FO{sub 3} formed by reaction of mobile fluorine atoms with ozone molecules trapped in an argon matrix

    SciTech Connect

    Misochko, E.Y.; Akimov, A.V.; Wight, C.A.

    1999-10-07

    Chemical reaction of F atoms with O{sub 3} molecules in a solid argon matrix was studied with FTIR spectroscopy. Fluorine atoms were generated by UV photolysis of F{sub 2} molecules in dilute solutions of F{sub 2} and O{sub 3} in solid argon. The FO-O{sub 2} complex is observed for the first time as an intermediate product by reaction of mobile F atoms with isolated ozone molecules. The observed complex is characterized by two intense absorption bands at 1522 and 968 cm{sup {minus}1}. Use of isotopic mixtures {sup 16}O/{sup 18}O provides strong evidence for assignment of these bands to the O-O stretch and F-O stretch fundamentals of the complex, which are red-shifted by 34 and 61 cm{sup {minus}1}, respectively, from the corresponding values for O{sub 2} and FO. Photolysis at 532 nm leads to decay of the FO-O{sub 2} complexes and to the appearance of isolated free FO radicals.

  17. Spectroscopic far ultraviolet observations of transition zone instabilities and their possible role in a pre-flare energy build-up

    NASA Technical Reports Server (NTRS)

    Brueckner, G. E.; Patterson, N. P.; Scherrer, V. E.

    1976-01-01

    Highly flare-productive newly emerging active regions are characterized by numerous small low-lying loops which frequently show a chaotic pattern. Flare activity in such a region subsides as the chaotic loop structures relax and expand into a bipolar configuration. The transition zone in such an active region is highly unstable, as shown by broadened and shifted nonthermal line profiles of medium-ionized elements like Si III, Si IV, and C IV. These transition-zone instabilities, which occur as isolated events in active regions of low flare productivity, are often observed prior to flares. Transition-zone instabilities can be traced to the footpoints of active loops and seem to be accompanied by heating of the loop. The loops vary in size and show differing degrees of activity, with the brightest and most compact ones seemingly being in a pre-flare state which results in the catastrophic energy release along the loop during a flare.

  18. Resolving Spectral Lines with a Periscope-Type DVD Spectroscope

    ERIC Educational Resources Information Center

    Wakabayashi, Fumitaka

    2008-01-01

    A new type of DVD spectroscope, the periscope type, is described and the numerical analysis of the observed emission and absorption spectra is demonstrated. A small and thin mirror is put inside and an eighth part of a DVD is used as a grating. Using this improved DVD spectroscope, one can observe and photograph visible spectra more easily and…

  19. Chronic multisite pain in adolescent girls and boys with emotional and behavioral problems: the Young-HUNT study.

    PubMed

    Skrove, Marit; Romundstad, Pål; Indredavik, Marit S

    2015-05-01

    The aim of this study was to assess the prevalence of chronic multisite pain with high disability in relation to emotional or behavioral problems and resilience factors in adolescence. A second aim was to investigate if resilience factors could attenuate the associations between psychiatric symptoms and chronic multisite pain. The study was based on a large cross-sectional study carried out in Norway between 2006 and 2008 and included 7,070 adolescents aged 13-19 years. Chronic multisite pain was defined as pain at least once a week during the last 3 months, scoring high on a disability index, and occurring in three or more locations. Chronic multisite pain was prevalent among adolescents with high scores (>85%) for anxiety/depression, social anxiety, conduct or attention problems (22.8-31.0 for girls, 8.8-19.0% for boys). Several coexistent psychiatric symptoms increased the prevalence of chronic multisite pain for both girls and boys. Resilience factors, including high self-esteem, seldom feeling lonely, and high scores for family cohesion or social competence, were associated with a lower prevalence and markedly attenuated the association between psychiatric symptoms and chronic multisite pain. Psychiatrists should be careful to assess and treat comorbid chronic pain in adolescents with emotional or behavioral problems. PMID:25138145

  20. Sonication effect on the reaction of 4-bromo-1-methylbenzene with sodium sulfide in liquid-liquid multi-site phase-transfer catalysis condition - kinetic study.

    PubMed

    Abimannan, Pachaiyappan; Selvaraj, Varathan; Rajendran, Venugopal

    2015-03-01

    The synthesis of di-p-tolylsulfane from the reaction of 4-bromo-1-methylbenzene (BMB) with sodium sulfide was carried out using a multi-site phase-transfer catalyst (MPTC) viz., 1,4-dihexyl-1,4-diazoniabicyclo[2.2.2]octanium dibromide and ultrasonic irradiation in a liquid-liquid reaction condition. The overall reaction rate is greatly enhanced when catalyzed by multi-site phase-transfer catalyst (MPTC) combined with sonication (40 kHz, 300 W) in a batch reactor than catalyzed by MPTC without sonication. Effects on the reaction due to various operating conditions, such as agitation speed, different ultrasound frequencies, different phase-transfer catalysts, different organic solvents, the amount of MPTC, temperature, amount of sodium sulfide, effect of sodium hydroxide, volume of n-hexane and the concentration of 4-bromo-1-methylbenzene. The reaction obeys a pseudo first-order rate law and a suitable mechanism was proposed based on the experimental observation. PMID:25199442

  1. Spectroscopic Observation of the Stardust Re-Entry in the Near UV with SLIT: Deduction of Surface Temperatures and Plasma Radiation

    NASA Technical Reports Server (NTRS)

    Winter, Michael W.; Trumble, Kerry A.

    2010-01-01

    Thermal radiation of the heat-shield and the emission of the post-shock layer around the Stardust capsule, during its re-entry, were detected by a NASA-led observation campaign aboard NASA's DC-8 airborne observatory involving teams from several nations. The German SLIT experiment used a conventional spectrometer, in a Czerny-Turner configuration (300 mm focal length and a 600 lines/mm grating), fed by fiber optics, to cover a wavelength range from 324 nm to 456 nm with a pixel resolution of 0.08 nm. The reentering spacecraft was tracked m uansuinaglly a camera with a view angle of 20 degrees, and light from the capsule was collected using a small mirror telescope with a view angle of only 0.45 degrees. Data were gathered with a measurement frequency of 5 Hz in a 30-second time interval around the point of maximum heating until the capsule left the field of view. The emission of CN (as a major ablation product), N2(+) and different atoms were monitored successfully during that time. Due to the nature of the experimental set up, spatial resolution of the radiation field was not possible. Therefore, all measured values represent an integration of radiation from the visible part of the glowing heat shield, and from the plasma in the post-shock region. Further, due to challenges in tracking not every spectrum gathered contained data. The measured spectra can be split up into two parts: (i) continuum spectra which represent a superposition of the heat shield radiation and the continuum radiation of potential dust particles in the plasma, and (ii) line spectra from the plasma in the shock layer. Planck temperatures (interpreted as the surface temperatures of the Stardust heat shield) were determined assuming either a constant surface temperature, or a temperature distribution deduced from numerical simulation. The constant surface temperatures are in good agreement with numerical simulations, but the peak values at the stagnation point are significantly lower than those

  2. Spectroscopic optical coherence elastography

    PubMed Central

    Adie, Steven G.; Liang, Xing; Kennedy, Brendan F.; John, Renu; Sampson, David D.; Boppart, Stephen A.

    2010-01-01

    We present an optical technique to image the frequency-dependent complex mechanical response of a viscoelastic sample. Three-dimensional hyperspectral data, comprising two-dimensional B-mode images and a third dimension corresponding to vibration frequency, were acquired from samples undergoing external mechanical excitation in the audio-frequency range. We describe the optical coherence tomography (OCT) signal when vibration is applied to a sample and detail the processing and acquisition techniques used to extract the local complex mechanical response from three-dimensional data that, due to a wide range of vibration frequencies, possess a wide range of sample velocities. We demonstrate frequency-dependent contrast of the displacement amplitude and phase of a silicone phantom containing inclusions of higher stiffness. Measurements of an ex vivo tumor margin demonstrate distinct spectra between adipose and tumor regions, and images of displacement amplitude and phase demonstrated spatially-resolved contrast. Contrast was also observed in displacement amplitude and phase images of a rat muscle sample. These results represent the first demonstration of mechanical spectroscopy based on B-mode OCT imaging. Spectroscopic optical coherence elastography (S-OCE) provides a high-resolution imaging capability for the detection of tissue pathologies that are characterized by a frequency-dependent viscoelastic response. PMID:21164898

  3. Spectroscopic optical coherence elastography.

    PubMed

    Adie, Steven G; Liang, Xing; Kennedy, Brendan F; John, Renu; Sampson, David D; Boppart, Stephen A

    2010-12-01

    We present an optical technique to image the frequency-dependent complex mechanical response of a viscoelastic sample. Three-dimensional hyperspectral data, comprising two-dimensional B-mode images and a third dimension corresponding to vibration frequency, were acquired from samples undergoing external mechanical excitation in the audio-frequency range. We describe the optical coherence tomography (OCT) signal when vibration is applied to a sample and detail the processing and acquisition techniques used to extract the local complex mechanical response from three-dimensional data that, due to a wide range of vibration frequencies, possess a wide range of sample velocities. We demonstrate frequency-dependent contrast of the displacement amplitude and phase of a silicone phantom containing inclusions of higher stiffness. Measurements of an ex vivo tumor margin demonstrate distinct spectra between adipose and tumor regions, and images of displacement amplitude and phase demonstrated spatially-resolved contrast. Contrast was also observed in displacement amplitude and phase images of a rat muscle sample. These results represent the first demonstration of mechanical spectroscopy based on B-mode OCT imaging. Spectroscopic optical coherence elastography (S-OCE) provides a high-resolution imaging capability for the detection of tissue pathologies that are characterized by a frequency-dependent viscoelastic response. PMID:21164898

  4. Calibration method for spectroscopic systems

    DOEpatents

    Sandison, David R.

    1998-01-01

    Calibration spots of optically-characterized material placed in the field of view of a spectroscopic system allow calibration of the spectroscopic system. Response from the calibration spots is measured and used to calibrate for varying spectroscopic system operating parameters. The accurate calibration achieved allows quantitative spectroscopic analysis of responses taken at different times, different excitation conditions, and of different targets.

  5. Calibration method for spectroscopic systems

    DOEpatents

    Sandison, D.R.

    1998-11-17

    Calibration spots of optically-characterized material placed in the field of view of a spectroscopic system allow calibration of the spectroscopic system. Response from the calibration spots is measured and used to calibrate for varying spectroscopic system operating parameters. The accurate calibration achieved allows quantitative spectroscopic analysis of responses taken at different times, different excitation conditions, and of different targets. 3 figs.

  6. Issues in Designing and Implementing a Spanish-Language Multi-Site Clinical Trial

    PubMed Central

    Suarez-Morales, Lourdes; Matthews, Julie; Martino, Steve; Ball, Samuel A.; Rosa, Carmen; Farentinos, Christine; Szapocznik, José; Carroll, Kathleen M.

    2013-01-01

    To address at least in part health disparities in Hispanic populations, the NIDA Clinical Trials Network implemented the first multi-site randomized clinical trial of substance abuse treatment conducted entirely in Spanish. This trial was intended to evaluate the effectiveness of Motivational Enhancement Therapy in a diverse population of Hispanics. In the conduct of this trial, several barriers to the successful implementation of a Spanish-language multi-site trial had to be addressed, including the appropriate translation of assessment instruments, shortage of appropriately trained Spanish-speaking clinical staff, and barriers to recruitment and retention of this population. To encourage similar research, strategies are described that were developed by the study team to meet these challenges. PMID:17612825

  7. From Controlled Trial to Community Adoption: The Multisite Translational Community Trial

    PubMed Central

    Murimi, Mary; Gonzalez, Anjelica; Njike, Valentine; Green, Lawrence W.

    2011-01-01

    Methods for translating the findings of controlled trials, such as the Diabetes Prevention Program, into real-world community application have not been clearly defined. A standardized research methodology for making and evaluating such a transition is needed. We introduce the multisite translational community trial (mTCT) as the research analog to the multisite randomized controlled trial. The mTCT is adapted to incorporate the principles and practices of community-based participatory research and the increased relevance and generalizability gained from diverse community settings. The mTCT is a tool designed to bridge the gap between what a clinical trial demonstrates can work in principle and what is needed to make it workable and effective in real-world settings. Its utility could be put to the test, in particular with practice-based research networks such as the Prevention Research Centers. PMID:21680935

  8. MASCARA: the multi-site all-sky CAameRA: concept and first results

    NASA Astrophysics Data System (ADS)

    Lesage, A.-L.; Spronck, J. F. P.; Stuik, R.; Bettonvil, F.; Pollaco, D.; Snellen, I. A. G.

    2014-07-01

    MASCARA, the Multi-site All-Sky CAmeRA, will consist of several fully-automated stations distributed across the globe. Its goal is to find exoplanets transiting the brightest stars, in the mV = 4 to 8 magnitude range, currently probed neither by space- nor by ground-based surveys. The nearby transiting planet systems that MASCARA is expected to discover will be key targets for future detailed planet atmosphere observations. The target population for MASCARA consists mostly of hot Jupiters. The main requirement set on MASCARA to detect these planets around stars down to magnitude 8 is to reach a minimum Signal-to-Noise Ratio of 100 within one hour of observation. Each MASCARA station consists of five low-noise off-the-shelf full-frame CCD cameras, fitted with standard Canon 24 mm , f/1.4 lenses, monitoring the near-entire sky down to magnitude 8 at that location. Measurements have demonstrated that the required Signal-to-Noise Ratio of 100, can be achieved in less than thirty minutes. MASCARA aims at deploying several stations world-wide to provide a nearly continuous coverage of the dark sky, at sub-minute cadence. While at the faint end MASCARA is limited mainly by photon noise, at the bright end scintillation and red noise become the limiting factors. Instrumental noise sources are reduced by placing the cameras in a fixed orientation and in a temperature controlled environment. By defocusing and allowing stars to drift over the detector, the impact of pixel-to-pixel variations on the photometry are minimized, while taking exposures at fixed sidereal times allows accurate cross-calibration of consecutive nights. The exposure time of 6.4 seconds gives rise to a high data acquisition rate of a MASCARA station, around 500GB per night. In order to minimize data transport and data storage requirements, the raw images are reduced to produce accurate light curves in nearly real time. The first MASCARA station will be integrated on La Palma during the summer of 2014

  9. Asiago spectroscopic classification of ASASSN-15db

    NASA Astrophysics Data System (ADS)

    Ochner, P.; Pastorello, A.; Benetti, S.; Cappellaro, E.; Elias-Rosa, N.; Tartaglia, L.; Terreran, G.; Tomasella, L.; Turatto, M.

    2015-02-01

    The Asiago Transient Classification Program (Tomasella et al. 2014, AN, 335, 841) reports the spectroscopic observation of ASASSN-15db in NGC 5996. The observation was performed with the Asiago 1.82m Copernico Telescope (+AFOSC; range 340-820 nm; resolution 1.4 nm), equipped with the CCD Andor IKON L936.

  10. Copula-based method for multisite monthly and daily streamflow simulation

    NASA Astrophysics Data System (ADS)

    Chen, Lu; Singh, Vijay P.; Guo, Shenglian; Zhou, Jianzhong; Zhang, Junhong

    2015-09-01

    Multisite stochastic simulation of streamflow sequences is needed for water resources planning and management. In this study, a new copula-based method is proposed for generating long-term multisite monthly and daily streamflow data. A multivariate copula, which is established based on bivariate copulas and conditional probability distributions, is employed to describe temporal dependences (single site) and spatial dependences (between sites). Monthly or daily streamflows at multiple sites are then generated by sampling from the conditional copula. Three tributaries of Colorado River and the upper Yangtze River are selected to evaluate the proposed methodology. Results show that the generated data at both higher and lower time scales can capture the distribution properties of the single site and preserve the spatial correlation of streamflows at different locations. The main advantage of the method is that the trivairate copula can be established using three bivariate copulas and the model parameters can be easily estimated using the Kendall tau rank correlation coefficient, which makes it possible to generate daily streamflow data. The method provides a new tool for multisite stochastic simulation.

  11. Copula-based method for Multisite Monthly and Daily Streamflow Simulation

    NASA Astrophysics Data System (ADS)

    Chen, L.; Dai, M.; Singh, V. P.; Guo, S.

    2014-12-01

    Multisite stochastic simulation of streamflow sequences is needed for water resources planning and management. In this study, a new copula-based method is proposed for generating long-term multisite monthly and daily streamflow data. A multivariate copula, which is established based on bivariate copulas and conditional probability distributions, is employed to describe temporal dependences (single site) and spatial dependences (between sites). Monthly or daily streamflows at multiple sites are then generated by sampling from the conditional copula. Three tributaries of Colorado River and the upper Yangtze River are selected to evaluate the proposed methodology. Results show that the generated data at both higher and lower time scales can capture the distribution properties of the single site and preserve the spatial correlation of streamflows at different locations. The main advantage of the method is that the model parameters can be easily estimated using Kendall tau rank correlation coefficient, which makes it possible to generate daily streamflow data. The method provides a new tool for multisite stochastic simulation.

  12. A Multi-Site Streamflow Forecast Framework: Application to the Upper Colorado River Basin

    NASA Astrophysics Data System (ADS)

    Bracken, C.; Rajagopalan, B.; Prairie, J.

    2007-12-01

    The multi-site streamflow forecast framework is a simple and parsimonious method for incorporating large-scale climate information into basin scale streamflow forecasts. The method is parsimonious because predictors need only be developed at one index gage, which is the sum of the seasonal flows at many spatial locations. In an application to the Upper Colorado River Basin (UCRB), multi-model ensemble (MME) forecasts were made of the seasonal (April-July) flows at the index gage. A K nearest-neighbor (KNN) nonparametric disaggregation technique is implemented which provides seasonal forecasts at four spatial locations and in turn monthly forecasts for the peak flow season (April-July). The predictions made in a retroactive forecast mode were comparable to the Colorado Basin River Forecast Center (CBRFC) predictions which are made using the Ensemble Streamflow Prediction (ESP) model. The earliest forecast of the ESP model is January 1 because of its heavy reliance on snowpack information. The multi-site framework provides skillful predictions as early as November 1 by its inclusion of large scale climate information such as geopotential height, zonal winds, meridional winds and sea surface temperature. It is possible that the ESP model and the multi-site framework could be combined in a Bayesian context that could incorporate professional judgment.

  13. MultiSite Gateway-Compatible Cell Type-Specific Gene-Inducible System for Plants1[OPEN

    PubMed Central

    Siligato, Riccardo; Wang, Xin; Yadav, Shri Ram; Lehesranta, Satu; Ma, Guojie; Ursache, Robertas; Sevilem, Iris; Zhang, Jing; Gorte, Maartje; Prasad, Kalika; Heidstra, Renze

    2016-01-01

    A powerful method to study gene function is expression or overexpression in an inducible, cell type-specific system followed by observation of consequent phenotypic changes and visualization of linked reporters in the target tissue. Multiple inducible gene overexpression systems have been developed for plants, but very few of these combine plant selection markers, control of expression domains, access to multiple promoters and protein fusion reporters, chemical induction, and high-throughput cloning capabilities. Here, we introduce a MultiSite Gateway-compatible inducible system for Arabidopsis (Arabidopsis thaliana) plants that provides the capability to generate such constructs in a single cloning step. The system is based on the tightly controlled, estrogen-inducible XVE system. We demonstrate that the transformants generated with this system exhibit the expected cell type-specific expression, similar to what is observed with constitutively expressed native promoters. With this new system, cloning of inducible constructs is no longer limited to a few special cases but can be used as a standard approach when gene function is studied. In addition, we present a set of entry clones consisting of histochemical and fluorescent reporter variants designed for gene and promoter expression studies. PMID:26644504

  14. Spectroscopic observations of ASASSN-14dc

    NASA Astrophysics Data System (ADS)

    Chen, T.-W.; Jerkstrand, A.; Smartt, S. J.; Inserra, C.; Bruce, A.; Lawrence, A.

    2014-06-01

    We report that a spectrogram of ASASSN-14dc (Holoien et al. ATel#6267) was obtained on Jun. 27.20 UT with the 4.2-m William Herschel Telescope + ISIS double armed spectograph with the R300B (0.86Angs per pix) and R158R (1.8 Angs per pix) gratings.The combined spectrum covers 3300 to 9990 Ang at a resolution (for 1 arcsec slit) about 1000 to 1300. ...

  15. Introduction of shared electronic records: multi-site case study using diffusion of innovation theory

    PubMed Central

    Stramer, Katja; Bratan, Tanja; Byrne, Emma; Mohammad, Yara; Russell, Jill

    2008-01-01

    Objective To explore the introduction of a centrally stored, shared electronic patient record (the summary care record (SCR)) in England and draw wider lessons about the implementation of large scale information technology projects in health care. Design Multi-site, mixed method case study applying utilisation focused evaluation. Setting Four early adopter sites for the SCR in England—three in urban areas of relative socioeconomic deprivation and the fourth in a relatively affluent rural area. Data sources and analysis Data included 250 staff interviews, 1500 hours of ethnographic observation, interviews and focus groups with 170 patients and carers, 2500 pages of correspondence and documentary evidence, and incorporation of relevant surveys and statistics produced by others. These were analysed by using a thematic approach drawing on (and extending) a theoretical model of complex change developed in a previous systematic review. Main findings The mixed fortunes of the SCR programme in its first year were largely explained by eight interacting influences. The first was the SCR’s material properties (especially technical immaturity and lack of interoperability) and attributes (especially the extent to which potential adopters believed the benefits outweighed the risks). The second was adopters’ concerns (especially about workload and the ethicality of sharing “confidential” information on an implied consent model). The third influence was interpersonal influence (for example, opinion leaders, champions, facilitators), and the fourth was organisational antecedents for innovation (for example past experience with information technology projects, leadership and management capacity, effective data capture systems, slack resources). The fifth was organisational readiness for the SCR (for example, innovation-system fit, tension for change, power balances between supporters and opponents, baseline data quality). The sixth was the implementation process (including

  16. Multisite, open-label, prospective trial of lamotrigine for geriatric bipolar depression: a preliminary report

    PubMed Central

    Sajatovic, Martha; Gildengers, Ariel; Jurdi, Rayan K Al; Gyulai, Laszlo; Cassidy, Kristin A; Greenberg, Rebecca L; Bruce, Martha L; Mulsant, Benoit H; Have, Thomas Ten; Young, Robert C

    2013-01-01

    Aims This is a multisite, 12-week, open-label trial of lamotrigine augmentation in 57 older adults (≥ 60 years; mean ± SD age = 66.5 ± 6.7 years) with either type I or type II bipolar depression. Methods Primary outcome measure was change from baseline on the Montgomery-Åsberg Depression Rating Scale (MADRS). Secondary outcome measures included Hamilton Depression Rating Scale (HAM-D), Clinical Global Impression-Bipolar version (CGI-BP), and the WHO-Disability Assessment Schedule II (WHO-DAS II). The Udvalg for Kliniske Undersøgelser (UKU) was used to assess side effects. Results A total of 77.2% of the study subjects had bipolar I disorder. The mean (SD) lamotrigine dose was 150.9 (68.5) mg/day. There was significant improvement in the MADRS, HAM-D, CGI-BP, and in most domains on the WHO-DAS II. For patients for whom final MADRS score was available: 31 (57.4%) met remission criteria and 35 (64.8%) met response criteria. There were 19/57 (33.3%) who dropped out of the study prematurely, with 6 dropouts due to adverse events (4 cases of rash, 1 manic switch, and 1 hyponatremia). Two cases of rash were possibly drug related and were resolved with drug discontinuation. The most common UKU adverse effects were reduced sleep duration (n = 14, 24.6%), weight loss (n = 12, 21.1%), increased dream activity (n = 12, 21.1%), polyuria/polydipsia (n = 11, 19.3%), weight gain (n = 9, 15.8%), diminished sexual desire (n = 9, 15.8%), increased sleep (n = 9, 15.8%), lassitude/fatigue (n = 8, 14%), and unsteady gait (n = 8, 14%). No significant changes in electrocardiogram or laboratory tests were observed. Conclusions In bipolar depressed elders, lamotrigine was associated with improvement in depression, psychopathology, and functional status. There was a moderate number of adverse events, although relationship of adverse events (particularly falls) to study medication could not be clearly determined in this uncontrolled trial. Controlled studies are needed to further

  17. Spectroscopic Classification of PS16ccj with Mayall/KOSMOS

    NASA Astrophysics Data System (ADS)

    Pan, Y.-C.; Foley, R. J.; Jha, S. W.; Rest, A.; Scolnic, D.

    2016-05-01

    We report the classification of PS16ccj from spectroscopic observation with KOSMOS on the Mayall telescope. The observation was made on 2016 May 05 UT. We classify PS16ccj as a SN Ia near maximum light.

  18. High-energy spectroscopic astrophysics

    NASA Astrophysics Data System (ADS)

    Güdel, Manuel; Walter, Roland

    After three decades of intense research in X-ray and gamma-ray astronomy, the time was ripe to summarize basic knowledge on X-ray and gamma-ray spectroscopy for interested students and researchers ready to become involved in new high-energy missions. This volume exposes both the scientific basics and modern methods of high-energy spectroscopic astrophysics. The emphasis is on physical principles and observing methods rather than a discussion of particular classes of high-energy objects, but many examples and new results are included in the three chapters as well.

  19. The CHARA Catalog of Orbital Elements of Spectroscopic Binary Stars

    NASA Astrophysics Data System (ADS)

    Taylor, Stuart F.; Harvin, James A.; McAlister, Harold A.

    2003-05-01

    Optical interferometry is entering a new age, with several ground-based long-baseline observatories now making observations of unprecedented resolution. Interferometers bring a new level of resolution to bear on spectroscopic binaries, enabling the full extraction of the physical parameters for the component stars with high accuracy. In the case of double-lined systems, a geometrically determined orbital parallax becomes available as well. The first step in preparing to observe spectroscopic binaries is to list them, which has not been done since the 1989 publication of the Eighth Catalogue of the Orbital Elements of Spectroscopic Binaries by Batten et al. We present a new catalog with roughly half again as many listings as the Eighth Catalogue. Angular separation predictions are made for each catalog entry. The numbers of spectroscopic binaries available for study as a function of several important observational parameters are explored, and in particular, the number of spectroscopic binaries as a function of expected separation is discussed.

  20. Fundamental spectroscopic studies of carbenes and hydrocarbon radicals

    SciTech Connect

    Gottlieb, C.A.; Thaddeus, P.

    1993-12-01

    Highly reactive carbenes and carbon-chain radicals are studied at millimeter wavelengths by observing their rotational spectra. The purpose is to provide definitive spectroscopic identification, accurate spectroscopic constants in the lowest vibrational states, and reliable structures of the key intermediates in reactions leading to aromatic hydrocarbons and soot particles in combustion.

  1. Process evaluation in a multisite, primary obesity-prevention trial in American Indian schoolchildren1–3

    PubMed Central

    Helitzer, Deborah L; Davis, Sally M; Gittelsohn, Joel; Going, Scott B; Murray, David M; Snyder, Patricia; Steckler, Allan B

    2016-01-01

    We describe the development, implementation, and use of the process evaluation component of a multisite, primary obesity prevention trial for American Indian schoolchildren. We describe the development and pilot testing of the instruments, provide some examples of the criteria for instrument selection, and provide examples of how process evaluation results were used to document and refine intervention components. The theoretical and applied framework of the process evaluation was based on diffusion theory, social learning theory, and the desire for triangulation of multiple modes of data collection. The primary objectives of the process evaluation were to systematically document the training process, content, and implementation of 4 components of the intervention. The process evaluation was developed and implemented collaboratively so that it met the needs of both the evaluators and those who would be implementing the intervention components. Process evaluation results revealed that observation and structured interviews provided the most informative data; however, these methods were the most expensive and time consuming and required the highest level of skill to undertake. Although the literature is full of idealism regarding the uses of process evaluation for formative and summative purposes, in reality, many persons are sensitive to having their work evaluated in such an in-depth, context-based manner as is described. For this reason, use of structured, quantitative, highly objective tools may be more effective than qualitative methods, which appear to be more dependent on the skills and biases of the researcher and the context in which they are used. PMID:10195608

  2. Multi-site phospho-regulation of proneural transcription factors controls proliferation versus differentiation in development and reprogramming

    PubMed Central

    Philpott, Anna

    2015-01-01

    During development of the nervous system, it is essential to co-ordinate the processes of proliferation and differentiation. Basic helix-loop-helix transcription factors play a central role in controlling neuronal differentiation and maturation as well as being components of the combinatorial code that determines neuronal identity. We have recently shown that the ability of the proneural proteins Ngn2 and Ascl1 to drive neuronal differentiation is inhibited by cyclin dependent kinase-mediated multi-site phosphorylation. This limits downstream target promoter dwell time, thus demonstrating a direct mechanistic regulatory link between the cell cycle and differentiation machinery.Proneural proteins are key components of transcription factor cocktails that can bring about the direct reprogramming of human fibroblasts into neurons. Building on our observations demonstrating that phospho-mutant proneural proteins show an enhanced ability to drive neuronal differentiation in vivo, we see that replacing wild-type with phospho-mutant proneural proteins in fibroblast reprogramming cocktails significantly enhances the axonal outgrowth, branching and electrophysiological maturity of the neurons generated. A model is presented here that can explain the enhanced ability of dephosphorylated proneural proteins to drive neuronal differentiation, and some unanswered questions in this emerging area are highlighted.

  3. Validation of Mismatch Negativity and P3a for Use in Multi-Site Studies of Schizophrenia: Characterization of Demographic, Clinical, Cognitive, and Functional Correlates in COGS-2

    PubMed Central

    Light, Gregory A.; Swerdlow, Neal R.; Thomas, Michael L.; Calkins, Monica E.; Green, Michael F.; Greenwood, Tiffany A.; Gur, Raquel E.; Gur, Ruben C.; Lazzeroni, Laura C.; Nuechterlein, Keith H.; Pela, Marlena; Radant, Allen D.; Seidman, Larry J.; Sharp, Richard F.; Siever, Larry J.; Silverman, Jeremy M.; Sprock, Joyce; Stone, William S.; Sugar, Catherine A.; Tsuang, Debby W.; Tsuang, Ming T.; Braff, David L.; Turetsky, Bruce I.

    2014-01-01

    Mismatch negativity (MMN) and P3a are auditory event-related potential (ERP) components that show robust deficits in schizophrenia (SZ) patients and exhibit qualities of endophenotypes, including substantial heritability, test-retest reliability, and trait-like stability. These measures also fulfill criteria for use as cognition and function-linked biomarkers in outcome studies, but have not yet been validated for use in large-scale multi-site clinical studies. This study tested the feasibility of adding MMN and P3a to the ongoing Consortium on the Genetics of Schizophrenia (COGS) study. The extent to which demographic, clinical, cognitive, and functional characteristics contribute to variability in MMN and P3a amplitudes was also examined. Participants (HCS n=824, SZ n=966) underwent testing at 5 geographically distributed COGS laboratories. Valid ERP data was obtained from 91% of HCS and 91% of SZ patients. Highly significant MMN (d=0.96) and P3a (d=0.93) amplitude reductions were observed in SZ patients, comparable in magnitude to those observed in single-lab studies with no appreciable differences across laboratories. Demographic characteristics accounted for 26% and 18% of the variance in MMN and P3a amplitudes, respectively. Significant relationships were observed among demographically-adjusted MMN and P3a measures and medication status as well as several clinical, cognitive, and functional characteristics of the SZ patients. This study demonstrates that MMN and P3a ERP biomarkers can be feasibly used in multi-site clinical studies. As with many clinical tests of brain function, demographic factors contribute to MMN and P3a amplitudes and should be carefully considered in future biomarker-informed clinical studies. PMID:25449710

  4. Exploring the Feasibility of Multi-Site Flow Cytometric Processing of Gut Associated Lymphoid Tissue with Centralized Data Analysis for Multi-Site Clinical Trials

    PubMed Central

    McGowan, Ian; Anton, Peter A.; Elliott, Julie; Cranston, Ross D.; Duffill, Kathryn; Althouse, Andrew D.; Hawkins, Kevin L.; De Rosa, Stephen C.

    2015-01-01

    The purpose of this study was to determine whether the development of a standardized approach to the collection of intestinal tissue from healthy volunteers, isolation of gut associated lymphoid tissue mucosal mononuclear cells (MMC), and characterization of mucosal T cell phenotypes by flow cytometry was sufficient to minimize differences in the normative ranges of flow parameters generated at two trial sites. Forty healthy male study participants were enrolled in Pittsburgh and Los Angeles. MMC were isolated from rectal biopsies using the same biopsy acquisition and enzymatic digestion protocols. As an additional comparator, peripheral blood mononuclear cells (PBMC) were collected from the study participants. For quality control, cryopreserved PBMC from a single donor were supplied to both sites from a central repository (qPBMC). Using a jointly optimized standard operating procedure, cells were isolated from tissue and blood and stained with monoclonal antibodies targeted to T cell phenotypic markers. Site-specific flow data were analyzed by an independent center which analyzed all data from both sites. Ranges for frequencies for overall CD4+ and CD8+ T cells, derived from the qPBMC samples, were equivalent at both UCLA and MWRI. However, there were significant differences across sites for the majority of T cell activation and memory subsets in qPBMC as well as PBMC and MMC. Standardized protocols to collect, stain, and analyze MMC and PBMC, including centralized analysis, can reduce but not exclude variability in reporting flow data within multi-site studies. Based on these data, centralized processing, flow cytometry, and analysis of samples may provide more robust data across multi-site studies. Centralized processing requires either shipping of fresh samples or cryopreservation and the decision to perform centralized versus site processing needs to take into account the drawbacks and restrictions associated with each method. PMID:26010577

  5. Asiago spectroscopic classification of AT 2016cvm

    NASA Astrophysics Data System (ADS)

    Tomasella, L.; Pastorello, A.; Benetti, S.; Cappellaro, E.; Elias-Rosa, N.; Ochner, P.; Tartaglia, L.; Terreran, G.; Turatto, M.

    2016-06-01

    The Asiago Transient Classification Program (Tomasella et al. 2014, AN, 335, 841) reports the spectroscopic classification of AT 2016cvm (also known as PTSS-16hxs), discovered 20160613.771 by the PMO-Tsinghua Supernova Survey (PTSS) The observation was performed with the Asiago 1.82 m Copernico Telescope (+AFOSC; range 340-820 nm; resolution 1.4 nm).

  6. Spectroscopic Classification of Three PSST Transients

    NASA Astrophysics Data System (ADS)

    Blanchard, P.; Nicholl, M.; Berger, E.; Fong, W.; Chornock, R.

    2016-04-01

    We obtained spectroscopic observations on 2016 April 6 UT (range 3000-10600 Angstroms) of three transients reported by the Pan-STARRS Survey for Transients (PSST; Huber et al., ATel #7153; http://star.pst.qub.ac.uk/ps1threepi/) using IMACS mounted on the 6.5m Magellan/Baade Telescope.

  7. Asiago spectroscopic classification of three SNe

    NASA Astrophysics Data System (ADS)

    Elias-Rosa, N.; Cappellaro, E.; Benetti, S.; Milan, M.; Miluzio, M.; Ochner, P.; Pastorello, A.; Tartaglia, L.; Terreran, G.; Tomasella, L.; Turatto, M.; Morales-Garoffolo, A.; Huang, F.

    2014-10-01

    The Asiago Transient Classification Program (Tomasella et al. 2014, AN, 335, 841) reports the spectroscopic classification of two SNe. The observations were performed with the Asiago 1.82 m Copernico Telescope (+AFOSC; range 340-820 nm; resolution 1.2 nm).

  8. Spectroscopic mode identification in gamma Doradus stars

    NASA Astrophysics Data System (ADS)

    Rylvia Pollard, Karen

    2015-08-01

    The MUSICIAN programme at the University of Canterbury has been successfully identifying frequencies and pulsation modes in many gamma Doradus stars using hundreds of precise, high resolution spectroscopic observations. This paper describes some of these frequency and mode identifications and the emerging patterns of the programme.

  9. Replication and Comparison of the Newly Proposed ADOS-2, Module 4 Algorithm in ASD Without ID: A Multi-site Study.

    PubMed

    Pugliese, Cara E; Kenworthy, Lauren; Bal, Vanessa Hus; Wallace, Gregory L; Yerys, Benjamin E; Maddox, Brenna B; White, Susan W; Popal, Haroon; Armour, Anna Chelsea; Miller, Judith; Herrington, John D; Schultz, Robert T; Martin, Alex; Anthony, Laura Gutermuth

    2015-12-01

    Recent updates have been proposed to the Autism Diagnostic Observation Schedule-2 Module 4 diagnostic algorithm. This new algorithm, however, has not yet been validated in an independent sample without intellectual disability (ID). This multi-site study compared the original and revised algorithms in individuals with ASD without ID. The revised algorithm demonstrated increased sensitivity, but lower specificity in the overall sample. Estimates were highest for females, individuals with a verbal IQ below 85 or above 115, and ages 16 and older. Best practice diagnostic procedures should include the Module 4 in conjunction with other assessment tools. Balancing needs for sensitivity and specificity depending on the purpose of assessment (e.g., clinical vs. research) and demographic characteristics mentioned above will enhance its utility. PMID:26385796

  10. Spectroscopic wear detector

    NASA Technical Reports Server (NTRS)

    Madzsar, George C. (Inventor)

    1993-01-01

    The elemental composition of a material exposed to hot gases and subjected to wear is determined. Atoms of an elemental species not appearing in this material are implanted in a surface at a depth based on the maximum allowable wear. The exhaust gases are spectroscopically monitored to determine the exposure of these atoms when the maximum allowable wear is reached.

  11. Reliability of an fMRI Paradigm for Emotional Processing in a Multisite Longitudinal Study

    PubMed Central

    Gee, Dylan G.; McEwen, Sarah C.; Forsyth, Jennifer K.; Haut, Kristen M.; Bearden, Carrie E.; Addington, Jean; Goodyear, Bradley; Cadenhead, Kristin S.; Mirzakhanian, Heline; Cornblatt, Barbara A.; Olvet, Doreen; Mathalon, Daniel H.; McGlashan, Thomas H.; Perkins, Diana O.; Belger, Aysenil; Seidman, Larry J.; Thermenos, Heidi; Tsuang, Ming T.; van Erp, Theo G.M.; Walker, Elaine F.; Hamann, Stephan; Woods, Scott W.; Constable, Todd; Cannon, Tyrone D.

    2015-01-01

    Multisite neuroimaging studies can facilitate the investigation of brain-related changes in many contexts, including patient groups that are relatively rare in the general population. Though multisite studies have characterized the reliability of brain activation during working memory and motor functional magnetic resonance imaging tasks, emotion processing tasks, pertinent to many clinical populations, remain less explored. A traveling participants study was conducted with eight healthy volunteers scanned twice on consecutive days at each of the eight North American Longitudinal Prodrome Study sites. Tests derived from generalizability theory showed excellent reliability in the amygdala (Eρ2=0.82), inferior frontal gyrus (IFG;Eρ2=0.83), anterior cingulate cortex (ACC;Eρ2=0.76), insula (Eρ2=0.85), and fusiform gyrus (Eρ2=0.91) for maximum activation and fair to excellent reliability in the amygdala (Eρ2=0.44), IFG (Eρ2=0.48), ACC (Eρ2=0.55), insula (Eρ2=0.42), and fusiform gyrus (Eρ2=0.83) for mean activation across sites and test days. For the amygdala, habituation (Eρ2=0.71) was more stable than mean activation. In a second investigation, data from 111 healthy individuals across sites were aggregated in a voxelwise, quantitative meta-analysis. When compared with a mixed effects model controlling for site, both approaches identified robust activation in regions consistent with expected results based on prior single-site research. Overall, regions central to emotion processing showed strong reliability in the traveling participants study and robust activation in the aggregation study. These results support the reliability of blood oxygen level-dependent signal in emotion processing areas across different sites and scanners and may inform future efforts to increase efficiency and enhance knowledge of rare conditions in the population through multisite neuroimaging paradigms. PMID:25821147

  12. Provider perceptions of knowledge exchange and communication in a multisite family health team

    PubMed Central

    Slater, Morgan; Nicholas, Emily; Leung, Fok-Han; Lofters, Aisha

    2016-01-01

    Abstract Objective To describe providers’ self-reported knowledge and use of family health team (FHT) services and to explore attitudes and perspectives about communication issues among health care professionals active within a large multisite FHT. Design Electronic questionnaire. Setting A multisite FHT in Toronto, Ont. Participants Health care professionals active within the FHT (N = 90). Main outcome measures The survey captured demographic characteristics, including the respondents’ roles and experience; knowledge about services available within the FHT; use of services; and perceived communication issues within the FHT. Results Forty-six health care professionals participated (51% response rate). While respondents were highly aware of the clinical resources and services offered at their own site of practice (95% agreed or strongly agreed), only 54% were aware of services offered at other sites within the FHT. Internal referrals for certain specialty services were high (ie, methadone management, obstetric care, intrauterine device insertion, and psychiatry), but less than 50% of other referrals (ie, sports medicine, joint injections, or tropical medicine) were to physicians within the FHT, despite physicians within the FHT offering services in these areas of expertise. Only 60% of respondents believed that patients had equal access to all of the services within the FHT, and 42% agreed or strongly agreed that patients were unlikely to travel between sites to access services. Roughly one-quarter of respondents believed that physicians were unlikely to refer patients to another site within the FHT to receive health care services. Most respondents agreed that the geographic distribution of the sites negatively affected communication within the FHT (68% agreed or strongly agreed). Conclusion Geographic dispersion of team members in a multisite FHT had a negative effect on provider knowledge of available services, perceived patient access to services, and

  13. Predictive risk factors for chronic regional and multisite musculoskeletal pain: a 5-year prospective study in a working population.

    PubMed

    Herin, Fabrice; Vézina, Michel; Thaon, Isabelle; Soulat, Jean-Marc; Paris, Christophe

    2014-05-01

    The role of psychosocial and physical factors in the development of musculoskeletal pain (MSP) has now been clearly demonstrated. However, it is unclear whether these factors contribute to specific regional MSP or to multisite pain. The main goal of this study was to assess the impact of work-related factors according to gender on the development of regional and multisite MSP. A total of 12,591 subjects (65% men and 35% women) who were born in 1938, 1943, 1948, and 1953 and were participating in a French longitudinal prospective epidemiological survey (ESTEV) in 1990 to 1995 were eligible. Personal factors and work exposure were assessed by self-administered questionnaires. Statistical associations between chronic MSP (regional body site or multisite), personal factors, and occupational factors were analyzed using logistic regression modeling. The incidence of regional MSP and multisite pain in 1995 were, respectively, 17% and 25.6%. For women, highly repetitive movements predicted neck/shoulder pain; posture and vibrations predicted arm and low back pain; and effort with tools predicted arm pain. For men, forceful effort and vibrations predicted neck/shoulder pain; posture and forceful effort predicted lower limb and low back pain; and forceful effort and effort with tools predicted arm pain. Physical constraints (ie, forceful effort or vibrations) were associated with multisite pain in both genders. Only for women, psychological factors were risk factors predictive of upper limb pain and in 3 or 4 painful anatomical sites. These results support the hypothesis that some physical and psychological work-related factors are predictive of regional or multisite MSP but differ according to gender. Gender differences and risk factors for work-related musculoskeletal pain should be also taken into account to more effectively target preventive measures. PMID:24561229

  14. The 2003-2004 multisite photometric campaign for the β Cephei and eclipsing star 16 (EN) Lacertae with an appendix on 2 Andromedae, the variable comparison star

    NASA Astrophysics Data System (ADS)

    Jerzykiewicz, M.; Handler, G.; Daszyńska-Daszkiewicz, J.; Pigulski, A.; Poretti, E.; Rodríguez, E.; Amado, P. J.; Kołaczkowski, Z.; Uytterhoeven, K.; Dorokhova, T. N.; Dorokhov, N. I.; Lorenz, D.; Zsuffa, D.; Kim, S.-L.; Bourge, P.-O.; Acke, B.; De Ridder, J.; Verhoelst, T.; Drummond, R.; Movchan, A. I.; Lee, J.-A.; Stȩślicki, M.; Molenda-Żakowicz, J.; Garrido, R.; Kim, S.-H.; Michalska, G.; Paparó, M.; Antoci, V.; Aerts, C.

    2015-11-01

    A multisite photometric campaign for the β Cephei and eclipsing variable 16 Lacertae is reported. 749 h of high-quality differential photoelectric Strömgren, Johnson and Geneva time series photometry were obtained with 10 telescopes during 185 nights. After removing the pulsation contribution, an attempt was made to solve the resulting eclipse light curve by means of the computer program EBOP. Although a unique solution was not obtained, the range of solutions could be constrained by comparing computed positions of the secondary component in the Hertzsprung-Russell diagram with evolutionary tracks. For three high-amplitude pulsation modes, the uvy and the Geneva UBG amplitude ratios are derived and compared with the theoretical ones for spherical-harmonic degrees ℓ ≤ 4. The highest degree, ℓ = 4, is shown to be incompatible with the observations. One mode is found to be radial, one is ℓ = 1, while in the remaining case ℓ = 2 or 3. The present multisite observations are combined with the archival photometry in order to investigate the long-term variation of the amplitudes and phases of the three high-amplitude pulsation modes. The radial mode shows a non-sinusoidal variation on a time-scale of 73 yr. The ℓ = 1 mode is a triplet with unequal frequency spacing, giving rise to two beat-periods, 720.7 d and 29.1 yr. The amplitude and phase of the ℓ = 2 or 3 mode vary on time-scales of 380.5 d and 43 yr. The light variation of 2 And, one of the comparison stars, is discussed in the appendix.

  15. Spontaneous intracranial hypotension and single entry multi-site epidural blood patch.

    PubMed

    Murphy, David; Chandna, Arjun; Laing, Andrew; MacFarlane, Martin

    2015-01-01

    The syndrome of spontaneous intracranial hypotension is often difficult to treat. Unfortunately, cerebrospinal fluid leaks are often numerous and difficult to detect radiologically. Multiple entries to the spinal epidural space, in an effort to alleviate symptoms, are therefore sometimes necessary. This case report details two patients treated successfully with a single lumbar entry point and the administration of a continuous multi-site epidural blood patch via a mobile catheter and their subsequent follow-up. These procedures are based on that first published by Ohtonari et al. in 2012. It is, to our knowledge, the first undertaken in Australasia. PMID:26396625

  16. The Benefits and Challenges of Preconsent in a Multisite, Pediatric Sickle Cell Intervention Trial.

    PubMed

    Nimmer, Mark; Czachor, Jason; Turner, Laura; Thomas, Bobbe; Woodford, Ashley L; Carpenter, Karli; Gonzalez, Victor; Liem, Robert I; Ellison, Angela; Casper, T Charles; Brousseau, David C

    2016-09-01

    Enrollment of patients in sickle cell intervention trials has been challenging due to difficulty in obtaining consent from a legal guardian and lack of collaboration between emergency medicine and hematology. We utilized education and preconsent in a pediatric multisite sickle cell intervention trial to overcome these challenges. Overall, 48 patients were enrolled after being preconsented. Variable Institutional Review Board policies related to preconsent validity and its allowable duration decreased the advantages of preconsent at some sites. The utility of preconsent for future intervention trials largely depends on local Institutional Review Board policies. Preeducation may also benefit the consent process, regardless of site differences. PMID:27081930

  17. Field fracturing multi-sites project. Annual technical progress report, July 28, 1993--July 31, 1994

    SciTech Connect

    Not Available

    1995-02-01

    The objective of the Field Fracturing Multi-Sites Project (M-Site) is to conduct experiments to definitively determine hydraulic fracture dimensions using remote well and treatment well diagnostic techniques. In addition, experiments will be conducted to provide data which will resolve significant unknowns with regard to hydraulic fracture modeling, fluid fracture rheology and fracture treatment design. These experiments will be supported by a well-characterized subsurface environment, as well as surface facilities and equipment that are conducive to acquiring high-quality data. The goal is to develop a fully characterized, tight reservoir-typical, field-scale hydraulic-fracturing test site.

  18. Mauna Kea Observatory infrared observations

    NASA Technical Reports Server (NTRS)

    Jefferies, J. T.

    1974-01-01

    Galactic and solar system infrared observations are reported using a broad variety of radiometric and spectroscopic instrumentation. Infrared programs and papers published during this period are listed.

  19. Spectroscopic Classifications of AT2016esx with Mayall/KOSMOS

    NASA Astrophysics Data System (ADS)

    Kilpatrick, C. D.; Siebert, M. R.; Coulter, D. A.; Foley, R. J.; Pan, Y.-C.; Jha, S. W.; Rest, A.; Scolnic, D.

    2016-08-01

    We report a classification of ASASSN-16io = AT2016esx from spectroscopic observations with KOSMOS on the KPNO Mayall 4-m telescope. Targets were supplied by the All-Sky Automated Survey for Supernovae (ASAS-SN).

  20. Spectroscopic Low Coherence Interferometry

    NASA Astrophysics Data System (ADS)

    Bosschaart, Nienke; van Leeuwen, T. G.; Aalders, Maurice C.; Hermann, Boris; Drexler, Wolfgang; Faber, Dirk J.

    Low-coherence interferometry (LCI) allows high-resolution volumetric imaging of tissue morphology and provides localized optical properties that can be related to the physiological status of tissue. This chapter discusses the combination of spatial and spectroscopic information by means of spectroscopic OCT (sOCT) and low-coherence spectroscopy (LCS). We describe the theory behind these modalities for the assessment of spatially resolved optical absorption and (back)scattering coefficient spectra. These spectra can be used for the highly localized quantification of chromophore concentrations and assessment of tissue organization on (sub)cellular scales. This leads to a wealth of potential clinical applications, ranging from neonatology for the determination of billibrubin concentrations, to oncology for the optical assessment of the aggressiveness of a cancerous lesion.

  1. A Phase 3 Placebo-Controlled, Double Blind, Multi-Site Trial of the alpha-2-adrenergic Agonist, Lofexidine, for Opioid Withdrawal

    PubMed Central

    Yu, Elmer; Miotto, Karen; Akerele, Evaristo; Montgomery, Ann; Elkashef, Ahmed; Walsh, Robert; Montoya, Ivan; Fischman, Marian W.; Collins, Joseph; McSherry, Frances; Boardman, Kathy; Davies, David K.; O’Brien, Charles P.; Ling, Walter; Kleber, Herbert; Herman, Barbara H.

    2008-01-01

    Context Lofexidine is an alpha-2-A noradrenergic receptor agonist that is approved in the United Kingdom for the treatment of opioid withdrawal symptoms. Lofexidine has been reported to have more significant effects on decreasing opioid withdrawal symptoms with less hypotension than clonidine. Objective To demonstrate that lofexidine is well tolerated and effective in the alleviation of observationally-defined opioid withdrawal symptoms in opioid dependent individuals undergoing medically supervised opioid detoxification as compared to placebo. Design An inpatient, Phase 3, placebo-controlled, double blind, randomized multi-site trial with three phases: (1) Opioid Agonist Stabilization Phase (days 1–3), (2) Detoxification/Medication or Placebo Phase (days 4–8), and (3) Post Detoxification/Medication Phase (days 9–11). Subjects Sixty-eight opioid dependent subjects were enrolled at three sites with 35 randomized to lofexidine and 33 to placebo. Main Outcome Measure Modified Himmelsbach Opiate Withdrawal Scale (MHOWS) on study day 5 (2nd opioid detoxification treatment day). Results Due to significant findings, the study was terminated early. On the study day 5 MHOWS, subjects treated with lofexidine had significantly lower scores (equating to fewer/less severe withdrawal symptoms) than placebo subjects (Least squares means 19.5 ± 2.1 versus 30.9 ± 2.7; p=0.0019). Lofexidine subjects had significantly better retention in treatment than placebo subjects (38.2% versus 15.2%; Log rank test p=0.01). Conclusions Lofexidine is well tolerated and more efficacious than placebo for reducing opioid withdrawal symptoms in inpatients undergoing medically supervised opioid detoxification. Trial Registration trial registry name A Phase 3 Placebo-Controlled, Double-Blind Multi-Site Trial of Lofexidine for Opiate Withdrawal, registration number NCT00032942, URL for the registry http://clinicaltrials.gov/ct/show/NCT00032942?order=4. PMID:18508207

  2. On the use of multi-algorithm, genetically adaptive multi-objective method for multi-site calibration of the SWAT model

    SciTech Connect

    Zhang, Xuesong; Srinivasan, Raghavan; Van Liew, M.

    2010-04-15

    With the availability of spatially distributed data, distributed hydrologic models are increasingly used for simulation of spatially varied hydrologic processes to understand and manage natural and human activities that affect watershed systems. Multi-objective optimization methods have been applied to calibrate distributed hydrologic models using observed data from multiple sites. As the time consumed by running these complex models is increasing substantially, selecting efficient and effective multi-objective optimization algorithms is becoming a nontrivial issue. In this study, we evaluated a multi-algorithm, genetically adaptive multi-objective method (AMALGAM) for multi-site calibration of a distributed hydrologic model—Soil and Water Assessment Tool (SWAT), and compared its performance with two widely used evolutionary multi-objective optimization (EMO) algorithms (i.e. Strength Pareto Evolutionary Algorithm 2 (SPEA2) and Non-dominated Sorted Genetic Algorithm II (NSGA-II)). In order to provide insights into each method’s overall performance, these three methods were tested in four watersheds with various characteristics. The test results indicate that the AMALGAM can consistently provide competitive or superior results compared with the other two methods. The multi-method search framework of AMALGAM, which can flexibly and adaptively utilize multiple optimization algorithms, makes it a promising tool for multi-site calibration of the distributed SWAT. For practical use of AMALGAM, it is suggested to implement this method in multiple trials with relatively small number of model runs rather than run it once with long iterations. In addition, incorporating different multiobjective optimization algorithms and multi-mode search operators into AMALGAM deserves further research.

  3. Methodological challenges in conducting a multi-site randomized clinical trial of massage therapy in hospice.

    PubMed

    Kutner, Jean; Smith, Marlaine; Mellis, Karen; Felton, Sue; Yamashita, Traci; Corbin, Lisa

    2010-06-01

    Researchers conducting multi-site studies of interventions for end-of-life symptom management face significant challenges with respect to obtaining an adequate sample and training and retaining on-site study teams. The purpose of this paper is to describe the strategies and responses to these challenges in a multi-site randomized clinical trial (RCT) of the efficacy of massage therapy for decreasing pain among patients with advanced cancer in palliative care/hospice settings. Over a period of 36 months, we enrolled 380 participants across 15 sites; 27% of whom withdrew prior to study completion (less than the anticipated 30% rate). We saw an average of 68% turnover amongst study staff. Three key qualities characterized successful on-site study teams: (1) organizational commitment; (2) strong leadership from on-site study coordinators; and (3) effective lines of communication between the on-site study coordinators and both their teams and the university-based research team. Issues of recruitment, retention and training should be accounted for in hospice-based research study design and budgeting. PMID:20597707

  4. Potential interoperability problems facing multi-site radiation oncology centers in The Netherlands

    NASA Astrophysics Data System (ADS)

    Scheurleer, J.; Koken, Ph; Wessel, R.

    2014-03-01

    Aim: To identify potential interoperability problems facing multi-site Radiation Oncology (RO) departments in the Netherlands and solutions for unambiguous multi-system workflows. Specific challenges confronting the RO department of VUmc (RO-VUmc), which is soon to open a satellite department, were characterized. Methods: A nationwide questionnaire survey was conducted to identify possible interoperability problems and solutions. Further detailed information was obtained by in-depth interviews at 3 Dutch RO institutes that already operate in more than one site. Results: The survey had a 100% response rate (n=21). Altogether 95 interoperability problems were described. Most reported problems were on a strategic and semantic level. The majority were DICOM(-RT) and HL7 related (n=65), primarily between treatment planning and verification systems or between departmental and hospital systems. Seven were identified as being relevant for RO-VUmc. Departments have overcome interoperability problems with their own, or with tailor-made vendor solutions. There was little knowledge about or utilization of solutions developed by Integrating the Healthcare Enterprise Radiation Oncology (IHE-RO). Conclusions: Although interoperability problems are still common, solutions have been identified. Awareness of IHE-RO needs to be raised. No major new interoperability problems are predicted as RO-VUmc develops into a multi-site department.

  5. Transmission heterogeneity and autoinoculation in a multisite infection model of HPV.

    PubMed

    Brouwer, Andrew F; Meza, Rafael; Eisenberg, Marisa C

    2015-12-01

    The human papillomavirus (HPV) is sexually transmitted and can infect oral, genital, and anal sites in the human epithelium. Here, we develop a multisite transmission model that includes autoinoculation to study HPV and other multisite diseases. Under a homogeneous-contacts assumption, we analyze the basic reproduction number R0, as well as type and target reproduction numbers, for a two-site model. In particular, we find that R0 occupies a space between taking the maximum of next generation matrix terms for same site transmission and taking the geometric average of cross-site transmission terms in such a way that heterogeneity in the same-site transmission rates increases R0 while heterogeneity in the cross-site transmission decreases it. Additionally, autoinoculation adds considerable complexity to the form of R0. We extend this analysis to a heterosexual population, which additionally yields dynamics analogous to those of vector-host models. We also examine how these issues of heterogeneity may affect disease control, using type and target reproduction numbers. PMID:26518265

  6. Normative data for multisite quantitative ultrasound: the Canadian Multicenter Osteoporosis Study.

    PubMed

    Olszynski, Wojciech P; Brown, Jacques P; Adachi, Jonathan D; Hanley, David A; Ioannidis, George; Davison, K Shawn

    2014-01-01

    Multisite quantitative ultrasound (mQUS) machines are attractive tools for assessing fragility fracture risk as they are often portable, comparatively inexpensive, require little training for their use, and emit no ionizing radiation. The primary objective of this investigation was to generate an mQUS normative database of speed of sound (SOS, in m/s) measures from a large sample of randomly selected community-based individuals. mQUS (BeamMed Omnisense MultiSite Quantitative Ultrasound 7000 S) measurements were obtained and assessed at the distal radius, tibia, and phalanx. All analyses were made separately for men and women and for each anatomical site. Scatterplots (SOS vs age) identified 30-39 yr of age as periods of both maximal SOS and of relative stability for all 3 sites over the age span investigated (30-96 yr of age; 2948 women and 1176 men) and, thus, was used as the "reference" population. For cross-sectional comparison of trends over aging, a number of age groupings were created: 30-39, 40-49, 50-59, 60-69, 70-79, and 80+ yr. In general, there were decreases in SOS over increasing age groupings. The normative data generated can be used to compare a given patient's mQUS measurement with reference to a young, healthy population, assigning them a gender-appropriate T-score. PMID:24169082

  7. Coarse-graining polymer solutions: A critical appraisal of single- and multi-site models

    NASA Astrophysics Data System (ADS)

    D'Adamo, G.; Menichetti, R.; Pelissetto, A.; Pierleoni, C.

    2015-09-01

    We critically discuss and review the general ideas behind single- and multi-site coarse-grained (CG) models as applied to macromolecular solutions in the dilute and semi-dilute regime. We first consider single-site models with zero-density and density-dependent pair potentials. We highlight advantages and limitations of each option in reproducing the thermodynamic behavior and the large-scale structure of the underlying reference model. As a case study we consider solutions of linear homopolymers in a solvent of variable quality. Secondly, we extend the discussion to multi-component systems presenting, as a test case, results for mixtures of colloids and polymers. Specifically, we found the CG model with zero-density potentials to be unable to predict fluid-fluid demixing in a reasonable range of densities for mixtures of colloids and polymers of equal size. For larger colloids, the polymer volume fractions at which phase separation occurs are largely overestimated. CG models with density-dependent potentials are somewhat less accurate than models with zero-density potentials in reproducing the thermodynamics of the system and, although they present a phase separation, they significantly underestimate the polymer volume fractions along the binodal. Finally, we discuss a general multi-site strategy, which is thermodynamically consistent and fully transferable with the number of sites, and that allows us to overcome most of the limitations discussed for single-site models.

  8. eGEMs: Pathways to Success for Multisite Clinical Data Research

    PubMed Central

    McGraw JD, Deven C.; Leiter JD, Alice B.

    2013-01-01

    There are numerous and significant challenges associated with leveraging electronic clinical data (ECD) for purposes beyond treating an individual patient and getting paid for that care. Optimizing this secondary use of clinical data is a key underpinning of many health reform goals and triggers numerous issues related to data stewardship and, more broadly, data governance. These challenges often involve legal, policy, and procedural issues related to the access, use, and disclosure of electronic health record (EHR) data for quality improvement and research. This paper contributes to the ongoing discussion of health data governance by detailing the experiences of nine multisite research initiatives across the country. The rich set of experiences from these initiatives, as well as a number of resources used by project participants to work through various challenges, are documented and collected here for others wishing to learn from their collective efforts. The paper does not attempt to catalog the full spectrum of governance issues that could potentially surface in the course of multisite research projects using ECD. Rather, the goal was to provide a snapshot in time of data-sharing challenges and navigation strategies, as well as validation that privacy-protective, legally compliant clinical data sharing across sites is currently possible. Finally, the paper also provides a foundation and framing for a broader community resource on governance—a “governance toolkit”—that will create a virtual space for the further discussion and sharing of promising practices. PMID:25848568

  9. Computerized cognitive remediation training for schizophrenia: an open label, multi-site, multinational methodology study.

    PubMed

    Murthy, N V; Mahncke, H; Wexler, B E; Maruff, P; Inamdar, A; Zucchetto, M; Lund, J; Shabbir, S; Shergill, S; Keshavan, M; Kapur, S; Laruelle, M; Alexander, R

    2012-08-01

    A recent single-site study (Fisher et al., 2009. Am J Psychiatry. 166 (7) 805-11) showed that repeated training with the Brain Fitness Program (BFP) improved performance on a battery of neuropsychological tasks. If replicated these data suggest an important non-pharmacological method for ameliorating cognitive impairment in schizophrenia. Our study evaluated the BFP training effects in an open-label, multi-site, multinational clinical trial. Fifty-five stable adult patients with schizophrenia on regular antipsychotic medication completed ≥ 32 BFP training sessions over 8-10 weeks. Training effects on cognitive performance and functional capacity outcome measures were measured using CogState® schizophrenia battery, UCSD Performance based Skills Assessment (UPSA-2) and Cognitive Assessment Interview (CAI). BFP training showed a large and significant treatment effect on a training exercise task (auditory processing speed), however this effect did not generalize to improved performance on independent CogState® assessment. There were no significant effects on UPSA-2 or CAI scores. Our study demonstrated the feasibility of implementing BFP training in a multi-site study. However, BFP training did not show significant treatment effects on cognitive performance or functional capacity outcome measures despite showing large and significant effects on a training exercise. PMID:22342330

  10. A multi-site approach towards integrating environmental management in the wine production industry.

    PubMed

    Walsdorff, A; van Kraayenburg, M; Barnardt, C A

    2005-01-01

    Nine wineries and a water bottling plant situated in the Franschhoek Valley, South Africa, have decided to lead the way towards creating a safer and more sustainable environment in the Valley. As part of the Vignerons de Franschhoek ECO Association (VFEA), they adopted a multi-site approach and obtained, in December 2003, the first ISO 14001 multi-site certification in South Africa. This proactive approach allows them better overall environmental performances through mutual motivation, information sharing and comparison of practices by the different participating organisations of Franschhoek Valley. At the initiation of the project, the major concerns were associated with a lack of sound environmental management and training of employees. Of particular concern was also the lack of monitoring and measurement of environmental performance key indicators, especially in water consumption and wastewater disposal areas. Although the system is still in its juvenile stage, it already showed some effluent quality improvements through better wastewater management, better control over chemical stores as well as definite improvement in water management and increase in solid wastes recycling. The latter improvements will definitely entail long-term cost savings should the system be continually and properly maintained. It is the intention of the VFEA to create a more environmentally friendly and sustainable Valley by convincing others to be more environmentally responsive and expanding the ISO 14001 principles to other areas of the organisations including the farms, to other wineries and ultimately to the whole Franschhoek Valley. PMID:15771100

  11. Performance of multisite silicon microprobes implanted chronically in the ventral cochlear nucleus of the cat.

    PubMed

    McCreery, Douglas; Lossinsky, Albert; Pikov, Victor

    2007-06-01

    A central auditory prosthesis based on microstimulation within the ventral cochlear nucleus (VCN) offers a means of restoring hearing to persons whose auditory nerve has been destroyed bilaterally and cannot benefit from cochlear implants. Arrays of silicon probes with 16 stimulating sites were implanted into the VCN of adult cats, for up to 314 days. Compound neuronal responses evoked from the sites in the VCN were recorded periodically in the central nucleus of the contralateral inferior colliculus (ICC). The threshold and growth of most of the responses were stable for at least 250 days after implantation of the arrays. The responses evoked from the deepest and shallowest electrode sites did exhibit some changes over time but none of the thresholds exceeded 10 microA. The thresholds and growth of the compound responses from most of the stimulating sites were very stable over time, and comparable to those of chronically implanted single-site iridium microelectrodes. Multiunit neuronal activity evoked from the stimulating sites in the VCN was recorded along the dorsolateral-ventromedial (DLVM) axis of the ICC. The distribution, span and degree of overlap of the multiunit activity demonstrated the utility of the multisite, multishank array configuration as a means of accessing the neuronal populations in the VCN that encode various acoustic frequencies. These findings are encouraging for the prospects of developing an auditory prosthesis employing multi-site silicon microprobes. PMID:17554823

  12. An Examination of Diversity within Three Southeastern Academic Libraries: A Mixed-Methods, Multi-Site Study

    ERIC Educational Resources Information Center

    Shaffer, Christopher A.

    2014-01-01

    The purpose of this study was to determine the extent to which three academic libraries in the Southeastern United States could be considered diverse. This was a multi-site, mixed methods study. It examined the climate and culture of the libraries, which was assessed through two methods; the first, through survey responses from full-time faculty…

  13. What Works Clearinghouse Quick Review: "Transfer Incentives for High-Performing Teachers: Final Results from a Multisite Experiment"

    ERIC Educational Resources Information Center

    What Works Clearinghouse, 2014

    2014-01-01

    "Transfer Incentives for High-Performing Teachers: Final Results from a Multisite Experiment," examined the impact of the Talent Transfer Initiative (TTI) on both student achievement and teacher retention in 10 school districts across seven states. The initiative gave bonuses to high-performing teachers for them to transfer to and stay…

  14. Development and Implementation of a Multisite Evaluation for the Women, Co-Occurring Disorders and Violence Study

    ERIC Educational Resources Information Center

    Giard, Julienne; Hennigan, Karen; Huntington, Nicholas; Vogel, Wendy; Rinehart, Debbie; Mazelis, Ruta; Nadlicki, Terri; Veysey, Bonita M.

    2005-01-01

    In this article we describe the development and implementation of the Substance Abuse and Mental Health Services Administration's (SAMHSA's) multisite Women, Co-Occurring Disorders and Violence Study (WCDVS), highlighting some of the challenges encountered, decisions made, and lessons learned. Four themes are discussed. First, the unique…

  15. Awareness of Diagnosis and Knowledge of HPV in Women Patients: Data from a Multi-Site Study

    ERIC Educational Resources Information Center

    McCree, Donna Hubbard; Daley, Ellen M.; Gorbach, Pamina; Hamm, Robert M.; Sharpe, Patricia A.; Brandt, Heather M.; McFarlane, Mary; Kerndt, Peter; McDermott, Robert J.; Perrin, Karen M.; St. Lawrence, Janet S.

    2010-01-01

    Background: Persistent infection with high-risk types of human papillomavirus (HPV) is associated with cervical and other anogenital cancers. Purpose: This paper reports results of awareness of an HPV diagnosis and HPV knowledge from a multi-site study of HPV knowledge, attitudes and behavior, and the impact of an HPV diagnosis on women and their…

  16. Collaborative Imaginaries and Multi-Sited Ethnography: Space-Time Dimensions of Engagement in an Afterschool Science Programme for Girls

    ERIC Educational Resources Information Center

    Rahm, Jrene

    2012-01-01

    Temporal and spatial configurations that constitute learning and identity work across practices have been little explored in studies of science literacy development. Grounded in multi-sited ethnography, this paper explores diverse girls' engagement with and identity work in science locally, inside a newsletter activity in an afterschool programme…

  17. Year One Results from the Multisite Randomized Evaluation of the i3 Scale-Up of Reading Recovery

    ERIC Educational Resources Information Center

    May, Henry; Gray, Abigail; Sirinides, Philip; Goldsworthy, Heather; Armijo, Michael; Sam, Cecile; Gillespie, Jessica N.; Tognatta, Namrata

    2015-01-01

    Reading Recovery (RR) is a short-term, one-to-one intervention designed to help the lowest achieving readers in first grade. This article presents first-year results from the multisite randomized controlled trial (RCT) and implementation study under the $55 million Investing in Innovation (i3) Scale-Up Project. For the 2011-2012 school year, the…

  18. Learning "about" and "from" Variation in Program Impacts Using Multisite Trials. MDRC Working Papers on Research Methodology

    ERIC Educational Resources Information Center

    Raudenbush, Stephen W.; Bloom, Howard S.

    2015-01-01

    The present paper, which is intended for a diverse audience of evaluation researchers, applied social scientists, and research funders, provides a broad overview of the conceptual and statistical issues involved in using multisite randomized trials to learn "about" and "from" variation in program effects across…

  19. Distortions in Distributions of Impact Estimates in Multi-Site Trials: The Central Limit Theorem Is Not Your Friend

    ERIC Educational Resources Information Center

    May, Henry

    2014-01-01

    Interest in variation in program impacts--How big is it? What might explain it?--has inspired recent work on the analysis of data from multi-site experiments. One critical aspect of this problem involves the use of random or fixed effect estimates to visualize the distribution of impact estimates across a sample of sites. Unfortunately, unless the…

  20. Multifunction Imaging and Spectroscopic Instrument

    NASA Technical Reports Server (NTRS)

    Mouroulis, Pantazis

    2004-01-01

    A proposed optoelectronic instrument would perform several different spectroscopic and imaging functions that, heretofore, have been performed by separate instruments. The functions would be reflectance, fluorescence, and Raman spectroscopies; variable-color confocal imaging at two different resolutions; and wide-field color imaging. The instrument was conceived for use in examination of minerals on remote planets. It could also be used on Earth to characterize material specimens. The conceptual design of the instrument emphasizes compactness and economy, to be achieved largely through sharing of components among subsystems that perform different imaging and spectrometric functions. The input optics for the various functions would be mounted in a single optical head. With the exception of a targeting lens, the input optics would all be aimed at the same spot on a specimen, thereby both (1) eliminating the need to reposition the specimen to perform different imaging and/or spectroscopic observations and (2) ensuring that data from such observations can be correlated with respect to known positions on the specimen. The figure schematically depicts the principal components and subsystems of the instrument. The targeting lens would collect light into a multimode optical fiber, which would guide the light through a fiber-selection switch to a reflection/ fluorescence spectrometer. The switch would have four positions, enabling selection of spectrometer input from the targeting lens, from either of one or two multimode optical fibers coming from a reflectance/fluorescence- microspectrometer optical head, or from a dark calibration position (no fiber). The switch would be the only moving part within the instrument.

  1. Efficacy of a Process Improvement Intervention on Inmate Awareness of HIV Services: A Multi-Site Trial

    PubMed Central

    Hiller, Matthew L.; Albizu-García, Carmen E.; Pich, Michele; Patterson, Yvonne; O’Connell, Daniel J.

    2015-01-01

    The prevalence of HIV among U.S. inmates is much greater than in the general population, creating public health concerns and cost issues for the criminal justice system. The HIV Services and Treatment Implementation in Corrections protocol of the NIDA funded Criminal Justice Drug Abuse Treatment Studies cooperative tested the efficacy of an organizational process improvement strategy on improving HIV services in correctional facilities. For this paper, we analyzed efficacy of this strategy on improving inmate awareness and perceptions of HIV services. The study used a multi-site (n=28) clustered randomized trial approach. Facilities randomized to the experimental condition used a coach-driven local change team approach to improve HIV services at their facility. Facilities in the control condition were given a directive to improve HIV services on their own. Surveys about awareness and perceptions of HIV services were administered anonymously to inmates who were incarcerated in study facilities at baseline (n=1253) and follow-up (n=1048). A series of one-way ANOVAs were run to test whether there were differences between inmates in the experimental and control facilities at baseline and follow-up. Differences were observed at baseline, with the experimental group having significantly lower scores than the control group on key variables. But, at post-test, following the intervention, these differences were no longer significant. Taken in context of the findings from the main study, these results suggest that the change team approach to improving HIV services in correctional facilities is efficacious for improving inmates’ awareness and perceptions of HIV services. PMID:26203411

  2. Spectroscopic Sensitivity Workout: First-order modes

    NASA Astrophysics Data System (ADS)

    Brown, Thomas

    2003-07-01

    We will observe the primary flux standards G191B2B, GD71 and GD153, obtaining first-order spectra in all L-modes {G191B2B only in the CCD modes due to its high brightness in the UV}. By comparing observed and model spectra, we will update calibration reference files describing spectroscopic sensitivity {and CTE loss} as a function of time. On visit of GD71 will be spent on verifying the recently derived CTE formula for STIS Spectroscopic modes with the CCD, by stepping the target along the slit {7 positions} with two {short} exposure times. This will verify the results using the two-amplifier readout method, and provide high-S/N data at low intensity levels and low background level.

  3. Multisite silicon neural probes with integrated silicon nitride waveguides and gratings for optogenetic applications

    NASA Astrophysics Data System (ADS)

    Shim, Euijae; Chen, Yu; Masmanidis, Sotiris; Li, Mo

    2016-03-01

    Optimal optogenetic perturbation of brain circuit activity often requires light delivery in a precise spatial pattern that cannot be achieved with conventional optical fibers. We demonstrate an implantable silicon-based probe with a compact light delivery system, consisting of silicon nitride waveguides and grating couplers for out-of-plane light emission with high spatial resolution. 473 nm light is coupled into and guided in cm-long waveguide and emitted at the output grating coupler. Using the direct cut-back and out-scattering measurement techniques, the propagation optical loss of the waveguide is measured to be below 3 dB/cm. The grating couplers provide collimated light emission with sufficient irradiance for neural stimulation. Finally, a probe with multisite light delivery with three output grating emitters from a single laser input is demonstrated.

  4. MACH14: A Multi-Site Collaboration on ART Adherence Among 14 Institutions

    PubMed Central

    Wilson, Ira B.; Goggin, Kathy; Reynolds, Nancy; Simoni, Jane M.; Golin, Carol E.; Rosen, Marc I.; Gross, Robert; Wagner, Glenn; Remien, Robert H.; Schneiderman, Neil; Erlen, Judith A.; Arnsten, Julia H.; Bangsberg, David R.

    2013-01-01

    The integration of original data from multiple antiretroviral (ARV) adherence studies offers a promising, but little used method to generate evidence to advance the field. This paper provides an overview of the design and implementation of MACH14, a collaborative, multi-site study in which a large data system has been created for integrated analyses by pooling original data from 16 longitudinal ARV adherence studies. Studies selected met specific criteria including similar research design and data domains such as adherence measured with medication event monitoring system, psychosocial factors related to adherence behavior, and virologic and clinical outcomes. The data system created contains individual data (collected between 1997 and 2009) from 2,860 HIV patients. Collaboration helped resolve the challenges inherent in pooling data across multiple studies, yet produced a data system with strong statistical power and potentially greater capacity to address key scientific questions than possible with single-sample studies or even meta-analytic designs. PMID:22864921

  5. North American Prodrome Longitudinal Study: a collaborative multisite approach to prodromal schizophrenia research.

    PubMed

    Addington, Jean; Cadenhead, Kristin S; Cannon, Tyrone D; Cornblatt, Barbara; McGlashan, Thomas H; Perkins, Diana O; Seidman, Larry J; Tsuang, Ming; Walker, Elaine F; Woods, Scott W; Heinssen, Robert

    2007-05-01

    This article presents the rationale, design, and preliminary findings of the North American Prodrome Longitudinal Study (NAPLS), a collaborative, multisite investigation into the earliest phase of psychotic illness. We describe how 8 independently conceived research projects were integrated methodologically, how diagnostic reliability was achieved across sites on the Structured Interview for Prodromal Syndromes, and how baseline and follow-up data were aggregated for 888 at risk and comparison subjects. Data are presented describing the demographic, academic/work, and diagnostic characteristics of 3 relevant subgroups: persons at heightened clinical risk for psychosis, help-seeking comparison subjects, and nonpsychiatric controls. The NAPLS data set will be used to explore a series of questions related to prodromal psychosis, including the descriptive phenomenology of currently accepted diagnostic criteria, conversion rates over a 30-month period, predictors of psychosis onset and functional disability, and the impact of early treatment on the course of prodromal symptoms. PMID:17255119

  6. Multi-site production planning in hybrid make-to-stock/make-to-order production environment

    NASA Astrophysics Data System (ADS)

    Rafiei, Hamed; Rabbani, Masoud; Kokabi, Reza

    2014-06-01

    Today competitive environment has enforced practitioners and researchers to pay great attention to issues enhancing both production and marketing competitiveness. To do so, it has been obligatory for the firms to consider production side activities while customer requirements are on the other side of competition. In this regard, hybrid make-to-stock (MTS)/make-to-order (MTO) production systems have revealed outstanding results. This paper addresses multi-site production planning of a hybrid manufacturing firm for the first time in the hybrid systems' body of literature. In this regard, a network of suppliers, manufacturers and customers is considered for which a mixed-integer mathematical model is proposed. Objective function of the proposed mathematical model seeks to maximize profitability of the manufacturing firm. Because of computational complexity of the developed mathematical model, a genetic algorithm is developed upon which numerical experiments are reported in order to show validity and applicability of the proposed model.

  7. Existence of multisite intrinsic localized modes in one-dimensional Debye crystals

    SciTech Connect

    Koukouloyannis, V.; Kourakis, I.

    2007-07-15

    The existence of highly localized multisite oscillatory structures (discrete multibreathers) in a nonlinear Klein-Gordon chain which is characterized by an inverse dispersion law is proven and their linear stability is investigated. The results are applied in the description of vertical (transverse, off-plane) dust grain motion in dusty plasma crystals, by taking into account the lattice discreteness and the sheath electric and/or magnetic field nonlinearity. Explicit values from experimental plasma discharge experiments are considered. The possibility for the occurrence of multibreathers associated with vertical charged dust grain motion in strongly coupled dusty plasmas (dust crystals) is thus established. From a fundamental point of view, this study aims at providing a rigorous investigation of the existence of intrinsic localized modes in Debye crystals and/or dusty plasma crystals and, in fact, suggesting those lattices as model systems for the study of fundamental crystal properties.

  8. Multisite silicon neural probes with integrated silicon nitride waveguides and gratings for optogenetic applications

    PubMed Central

    Shim, Euijae; Chen, Yu; Masmanidis, Sotiris; Li, Mo

    2016-01-01

    Optimal optogenetic perturbation of brain circuit activity often requires light delivery in a precise spatial pattern that cannot be achieved with conventional optical fibers. We demonstrate an implantable silicon-based probe with a compact light delivery system, consisting of silicon nitride waveguides and grating couplers for out-of-plane light emission with high spatial resolution. 473 nm light is coupled into and guided in cm-long waveguide and emitted at the output grating coupler. Using the direct cut-back and out-scattering measurement techniques, the propagation optical loss of the waveguide is measured to be below 3 dB/cm. The grating couplers provide collimated light emission with sufficient irradiance for neural stimulation. Finally, a probe with multisite light delivery with three output grating emitters from a single laser input is demonstrated. PMID:26941111

  9. A frailty-contagion model for multi-site hourly precipitation driven by atmospheric covariates

    NASA Astrophysics Data System (ADS)

    Koch, Erwan; Naveau, Philippe

    2015-04-01

    Accurate stochastic simulations of hourly precipitation are needed for impact studies at local spatial scales. Statistically, hourly precipitation data represent a difficult challenge. They are non-negative, skewed, heavy tailed, contain a lot of zeros (dry hours) and they have complex temporal structures (e.g., long persistence of dry episodes). Inspired by frailty-contagion approaches used in finance and insurance, we propose a multi-site precipitation simulator that, given appropriate regional atmospheric variables, can simultaneously handle dry events and heavy rainfall periods. One advantage of our model is its conceptual simplicity in its dynamical structure. In particular, the temporal variability is represented by a common factor based on a few classical atmospheric covariates like temperatures, pressures and others. Our inference approach is tested on simulated data and applied on measurements made in the northern part of French Brittany.

  10. Field fracturing multi-sites project. Annual report, August 1, 1995--July 31, 1996

    SciTech Connect

    1996-12-31

    The objective of the Field Fracturing Multi-Sites Project (M-Site) is to conduct experiments to definitively determine hydraulic fracture dimensions using remote well and treatment well diagnostic techniques. In addition, experiments are to be conducted to provide data that will resolve significant unknowns with regard to hydraulic fracture modeling, fracture fluid rheology and fracture treatment design. These experiments will be supported by a well-characterized subsurface environment, as well as surface facilities and equipment conducive to acquiring high-quality data. The primary Project goal is to develop a fully characterized, tight reservoir-typical, field-scale hydraulic fracturing test site to diagnose, characterize, and test hydraulic fracturing technology and performance. It is anticipated that the research work being conducted by the multi-disciplinary team of GRI and DOE contractors will lead to the development of a commercial fracture mapping tool/service.

  11. Multisite silicon neural probes with integrated silicon nitride waveguides and gratings for optogenetic applications.

    PubMed

    Shim, Euijae; Chen, Yu; Masmanidis, Sotiris; Li, Mo

    2016-01-01

    Optimal optogenetic perturbation of brain circuit activity often requires light delivery in a precise spatial pattern that cannot be achieved with conventional optical fibers. We demonstrate an implantable silicon-based probe with a compact light delivery system, consisting of silicon nitride waveguides and grating couplers for out-of-plane light emission with high spatial resolution. 473 nm light is coupled into and guided in cm-long waveguide and emitted at the output grating coupler. Using the direct cut-back and out-scattering measurement techniques, the propagation optical loss of the waveguide is measured to be below 3 dB/cm. The grating couplers provide collimated light emission with sufficient irradiance for neural stimulation. Finally, a probe with multisite light delivery with three output grating emitters from a single laser input is demonstrated. PMID:26941111

  12. Neisseria meningitidis Type IV Pili Composed of Sequence Invariable Pilins Are Masked by Multisite Glycosylation.

    PubMed

    Gault, Joseph; Ferber, Mathias; Machata, Silke; Imhaus, Anne-Flore; Malosse, Christian; Charles-Orszag, Arthur; Millien, Corinne; Bouvier, Guillaume; Bardiaux, Benjamin; Péhau-Arnaudet, Gérard; Klinge, Kelly; Podglajen, Isabelle; Ploy, Marie Cécile; Seifert, H Steven; Nilges, Michael; Chamot-Rooke, Julia; Duménil, Guillaume

    2015-09-01

    The ability of pathogens to cause disease depends on their aptitude to escape the immune system. Type IV pili are extracellular filamentous virulence factors composed of pilin monomers and frequently expressed by bacterial pathogens. As such they are major targets for the host immune system. In the human pathogen Neisseria meningitidis, strains expressing class I pilins contain a genetic recombination system that promotes variation of the pilin sequence and is thought to aid immune escape. However, numerous hypervirulent clinical isolates express class II pilins that lack this property. This raises the question of how they evade immunity targeting type IV pili. As glycosylation is a possible source of antigenic variation it was investigated using top-down mass spectrometry to provide the highest molecular precision on the modified proteins. Unlike class I pilins that carry a single glycan, we found that class II pilins display up to 5 glycosylation sites per monomer on the pilus surface. Swapping of pilin class and genetic background shows that the pilin primary structure determines multisite glycosylation while the genetic background determines the nature of the glycans. Absence of glycosylation in class II pilins affects pilus biogenesis or enhances pilus-dependent aggregation in a strain specific fashion highlighting the extensive functional impact of multisite glycosylation. Finally, molecular modeling shows that glycans cover the surface of class II pilins and strongly decrease antibody access to the polypeptide chain. This strongly supports a model where strains expressing class II pilins evade the immune system by changing their sugar structure rather than pilin primary structure. Overall these results show that sequence invariable class II pilins are cloaked in glycans with extensive functional and immunological consequences. PMID:26367394

  13. The brain-derived neurotrophic factor pathway, life stress, and chronic multi-site musculoskeletal pain

    PubMed Central

    Milaneschi, Yuri; Jansen, Rick; Elzinga, Bernet M; Dekker, Joost; Penninx, Brenda WJH

    2016-01-01

    Introduction Brain-derived neurotrophic factor (BDNF) disturbances and life stress, both independently and in interaction, have been hypothesized to induce chronic pain. We examined whether (a) the BDNF pathway (val66met genotype, gene expression, and serum levels), (b) early and recent life stress, and (c) their interaction are associated with the presence and severity of chronic multi-site musculoskeletal pain. Methods Cross-sectional data are from 1646 subjects of the Netherlands Study of Depression and Anxiety. The presence and severity of chronic multi-site musculoskeletal pain were determined using the Chronic Pain Grade (CPG) questionnaire. The BDNF val66met polymorphism, BDNF gene expression, and BDNF serum levels were measured. Early life stress before the age of 16 was assessed by calculating a childhood trauma index using the Childhood Trauma Interview. Recent life stress was assessed as the number of recent adverse life events using the List of Threatening Events Questionnaire. Results Compared to val66val, BDNF met carriers more often had chronic pain, whereas no differences were found for BDNF gene expression and serum levels. Higher levels of early and recent stress were both associated with the presence and severity of chronic pain (p < 0.001). No interaction effect was found for the BDNF pathway with life stress in the associations with chronic pain presence and severity. Conclusions This study suggests that the BDNF gene marks vulnerability for chronic pain. Although life stress did not alter the impact of BDNF on chronic pain, it seems an independent factor in the onset and persistence of chronic pain. PMID:27145806

  14. Work related and psychological determinants of multi-site musculoskeletal pain

    PubMed Central

    Solidaki, Eleni; Chatzi, Leda; Bitsios, Panos; Markatzi, Irini; Plana, Estel; Castro, Francesc; Palmer, Keith; Coggon, David; Kogevinas, Manolis

    2011-01-01

    Objectives Musculoskeletal pain is associated with occupational physical activities and psychosocial risk factors. We evaluated the relative importance of work-related and psychological determinants of the number of anatomical sites affected by musculoskeletal pain in a cross-sectional survey. Methods The survey focused on musculoskeletal pain in six body regions (low-back, neck, shoulder, elbow, wrist/hand and knee) among 224 nurses, 200 office workers and 140 postal clerks in Crete (response rate 95%). Information was collected about demographic characteristics, occupational physical load, psychosocial aspects of work, perceptions about causes of pain, mental health, tendency to somatize, and experience of pain in the past 12 months. Poisson regression was used to assess associations of risk factors with the number of painful anatomical sites and interactions were explored using classification and regression trees (CART). Results Two-thirds of the study sample reported pain in at least two body sites during the past 12 months, and in 23%, more than three sites were affected. The number of painful anatomical sites was strongly related to both physical load at work and somatizing tendency (with relative risks increased five-fold or more for frequent and disabling multisite pain) , and was also significantly associated with work-related psychosocial factors, and beliefs about work causation. The CART analysis suggested that in the population studied, the leading determinant of the number of painful body sites was somatizing tendency. Conclusions In the population studied, pain at multiple anatomical sites is common, and is strongly associated with somatizing tendency, which may have a more important influence on multi-site pain than on pain that is limited to a single anatomical site. PMID:20011982

  15. Neisseria meningitidis Type IV Pili Composed of Sequence Invariable Pilins Are Masked by Multisite Glycosylation

    PubMed Central

    Gault, Joseph; Ferber, Mathias; Machata, Silke; Imhaus, Anne-Flore; Malosse, Christian; Charles-Orszag, Arthur; Millien, Corinne; Bouvier, Guillaume; Bardiaux, Benjamin; Péhau-Arnaudet, Gérard; Klinge, Kelly; Podglajen, Isabelle; Ploy, Marie Cécile; Seifert, H. Steven; Nilges, Michael; Chamot-Rooke, Julia; Duménil, Guillaume

    2015-01-01

    The ability of pathogens to cause disease depends on their aptitude to escape the immune system. Type IV pili are extracellular filamentous virulence factors composed of pilin monomers and frequently expressed by bacterial pathogens. As such they are major targets for the host immune system. In the human pathogen Neisseria meningitidis, strains expressing class I pilins contain a genetic recombination system that promotes variation of the pilin sequence and is thought to aid immune escape. However, numerous hypervirulent clinical isolates express class II pilins that lack this property. This raises the question of how they evade immunity targeting type IV pili. As glycosylation is a possible source of antigenic variation it was investigated using top-down mass spectrometry to provide the highest molecular precision on the modified proteins. Unlike class I pilins that carry a single glycan, we found that class II pilins display up to 5 glycosylation sites per monomer on the pilus surface. Swapping of pilin class and genetic background shows that the pilin primary structure determines multisite glycosylation while the genetic background determines the nature of the glycans. Absence of glycosylation in class II pilins affects pilus biogenesis or enhances pilus-dependent aggregation in a strain specific fashion highlighting the extensive functional impact of multisite glycosylation. Finally, molecular modeling shows that glycans cover the surface of class II pilins and strongly decrease antibody access to the polypeptide chain. This strongly supports a model where strains expressing class II pilins evade the immune system by changing their sugar structure rather than pilin primary structure. Overall these results show that sequence invariable class II pilins are cloaked in glycans with extensive functional and immunological consequences. PMID:26367394

  16. The mass ratio in spectroscopic binaries

    NASA Astrophysics Data System (ADS)

    Ducati, J. R.; Penteado, E. M.; Turcati, R.

    2003-08-01

    The process of formation of binary and multiple stars is not yet fully understood. Possibilities range from simultaneous processes of condensation from the primeval nebula, to isolated star formation and eventual capture to form a double system. Models exist that predict success probabilities for each theoretical process, and comparison with observational data is crucial. Spectroscopic binaries are specially suited to be used as observational data, since several biases that can arise from general catalogues of binary stars can be avoided, including dominance of systems with large separations between components. A very important parameter in these studies is the mass ratio, the quocient of the masses of primary and secundary members. The histogram of mass ratios provides crucial information to models of binary formation, linked to condensation processes and evolutionaty rates.In this case, spectroscopic binaries can be chosen as the observational sample, provided that the spectrum of the primary is from a non-evolved, main-sequence star,whose mass can be derived reliably from its spectral type. Defining an adequate limiting magnitude (6.5), one avoids bias from eclipsing systems with high inclinations, since nearly all systems up to 6.5 mag were detected. In this paper, a critical review is presented of the existing methods for deriving the distribution of the mass ratios from spectroscopic binary orbital data. After showing the incorrectness of some results published in the litterature, the available data (Batten's 8th Catalogue, 1989) is discussed. Simulations for several distributions of mass ratios (constant, quadratic, etc) are performed. It is shown that the existing data permits only to assert that the spectroscopic binaries with small mass ratios (q < 0.4) are more frequent that those with large mass ratios (q = 0.9 to 1.0).

  17. THE zCOSMOS 10k-BRIGHT SPECTROSCOPIC SAMPLE

    SciTech Connect

    Lilly, Simon J.; Maier, Christian; Carollo, Marcella; Caputi, Karina; Le Brun, Vincent; Kneib, Jean-Paul; Le Fevre, Olivier; De la Torre, Sylvain; De Ravel, Loic; Mainieri, Vincenzo; Mignoli, Marco; Zamorani, Gianni; Bardelli, Sandro; Bolzonella, Micol; Coppa, Graziano; Scodeggio, Marco; Contini, Thierry; Bongiorno, Angela; Cucciati, Olga

    2009-10-01

    We present spectroscopic redshifts of a large sample of galaxies with I {sub AB} < 22.5 in the COSMOS field, measured from spectra of 10,644 objects that have been obtained in the first two years of observations in the zCOSMOS-bright redshift survey. These include a statistically complete subset of 10,109 objects. The average accuracy of individual redshifts is 110 km s{sup -1}, independent of redshift. The reliability of individual redshifts is described by a Confidence Class that has been empirically calibrated through repeat spectroscopic observations of over 600 galaxies. There is very good agreement between spectroscopic and photometric redshifts for the most secure Confidence Classes. For the less secure Confidence Classes, there is a good correspondence between the fraction of objects with a consistent photometric redshift and the spectroscopic repeatability, suggesting that the photometric redshifts can be used to indicate which of the less secure spectroscopic redshifts are likely right and which are probably wrong, and to give an indication of the nature of objects for which we failed to determine a redshift. Using this approach, we can construct a spectroscopic sample that is 99% reliable and which is 88% complete in the sample as a whole, and 95% complete in the redshift range 0.5 < z < 0.8. The luminosity and mass completeness levels of the zCOSMOS-bright sample of galaxies is also discussed.

  18. A general Bayesian framework for calibrating and evaluating stochastic models of annual multi-site hydrological data

    NASA Astrophysics Data System (ADS)

    Frost, Andrew J.; Thyer, Mark A.; Srikanthan, R.; Kuczera, George

    2007-07-01

    SummaryMulti-site simulation of hydrological data are required for drought risk assessment of large multi-reservoir water supply systems. In this paper, a general Bayesian framework is presented for the calibration and evaluation of multi-site hydrological data at annual timescales. Models included within this framework are the hidden Markov model (HMM) and the widely used lag-1 autoregressive (AR(1)) model. These models are extended by the inclusion of a Box-Cox transformation and a spatial correlation function in a multi-site setting. Parameter uncertainty is evaluated using Markov chain Monte Carlo techniques. Models are evaluated by their ability to reproduce a range of important extreme statistics and compared using Bayesian model selection techniques which evaluate model probabilities. The case study, using multi-site annual rainfall data situated within catchments which contribute to Sydney's main water supply, provided the following results: Firstly, in terms of model probabilities and diagnostics, the inclusion of the Box-Cox transformation was preferred. Secondly the AR(1) and HMM performed similarly, while some other proposed AR(1)/HMM models with regionally pooled parameters had greater posterior probability than these two models. The practical significance of parameter and model uncertainty was illustrated using a case study involving drought security analysis for urban water supply. It was shown that ignoring parameter uncertainty resulted in a significant overestimate of reservoir yield and an underestimation of system vulnerability to severe drought.

  19. Spectroscopic investigations of heme proteins

    NASA Astrophysics Data System (ADS)

    Ogilvie, Jennifer Pauline

    Using several novel spectroscopic techniques, we investigate the dynamics of heme proteins over the full range of time scales relevant to their function. With ˜10 femtosecond time resolution we use ultrafast pump-probe spectroscopy to gain insight into the earliest dynamics initiated by the photodissociation of the carbon monoxide ligand from myoglobin. Coherent oscillations that are driven by the bond-breaking event reveal several vibrational modes of the heme that provide the driving force for the initial motions along the pathway to protein function. Much later along this pathway we address the question of ligand escape from myoglobin. With this purpose we develop heterodyne-detected diffractive-optics-based phase-grating spectroscopy, which provides more than 2 orders of magnitude increase in sensitivity for the measurement of volume changes and energetics. The improved sensitivity allows us to directly observe the ligand escape, which occurs via a number of discrete routes through the protein. Following the escape process, we observe the full cycle of dynamics that is complete when the carbon monoxide ligand rebinds to the protein. Using a resonant probe we re-examine the dynamics of ligand escape from myoglobin using transient absorption and transient-grating spectroscopy. This study confirms the findings of the previous off-resonant work, and allows us to explore the relationship between the observables in the phase-grating experiment and other resonant spectroscopies. The various dynamical processes of myoglobin provide a basis for understanding the structure/function relationship at the single protein level. This lays the foundation for a description of protein-protein interactions such as cooperativity in hemoglobin.

  20. Spectroscopic investigations of dithienyl polyenes

    NASA Astrophysics Data System (ADS)

    Cooper, Thomas M.; Sowards, Laura A.; Natarajan, Lalgudi V.; Kirkpatrick, Sean M.; Chandra, Suresh; McLean, Daniel G.; Spangler, Charles W.

    1999-10-01

    To understand the photophysics of nonlinear absorbers, we have investigated the photophysics of a series of di(2- thienyl-3,3',4,4'-butyl)polyenes. Spectroscopic measurements, including UV/Vis, fluorescence, fluorescence lifetimes, fluorescence quantum yields, triplet state lifetime, solvent effects and two-photon absorption coefficient were obtained as a function of the number of double bonds (n equals 1 - 5). Trends in the data reflected the ordering, energy gap between and mixing of 1Bu* and 1Ag* excited state configurations. We investigated the solvatochromism of a series of (alpha) ,(omega) -di(2- dithienyl 3,3',4,4'-butyl) polyenes. Absorption (n equals 1 - 5 double bonds) were collected in a series of aprotic solvents. The absorption energy dispersion effect sensitivity increased smoothly with n, reaching asymptotic behavior as n approached 5. The emission energy had less solvent sensitivity, giving evidence for a polar 1Bu* absorbing state and a nonpolar 1Ag* emitting state. We observed sensitivity of the absorbing and emitting states to solute-solvent dipole-dipole interactions, suggesting the dithienyl polyenes had a polar syn ground state conformation.

  1. Quasi-static and multi-site high velocity impact response of composite structures

    NASA Astrophysics Data System (ADS)

    Deka, Lakshya

    Understanding of low and high velocity transverse impact of laminated fiber reinforced composites is of interest in military, aerospace, marine and civilian structures. Recent advances in the field of numerical simulation provide a means of predicting the performance characteristics of layered materials for impact protection. The overall objective of this work is to investigate the behavior of laminated composites which include both thermoplastic and thermoset systems subjected to quasi-static, low and high velocity impact; both from an experimental and numerical modeling view point. To analyze this problem, a series of quasi-static, low and high velocity impact tests have been performed on laminated composite plates namely E-glass/polypropylene, S2-glass/epoxy and carbon/polyphenylene sulphide. To analyze the perforation mechanism, ballistic limit and damage evolution, an explicit three-dimensional finite element code LS-DYNA is used. Selecting proper material models and contact definition is one of the major criteria for obtaining accurate numerical simulation. Material model 162 (MAT 162), a progressive failure model based on modified Hashin's criteria and continuum damage mechanics (CDM) has been assigned to predict failure of the laminate. This approach is used because during transverse impact, a composite laminate undergoes progressive damage. The laminate and the projectile are meshed using brick elements with single integration points. The impact velocity ranges from 180 to 400 m s -1. This work focuses on three main aspects; (i) To obtain static and dynamic material properties to incorporate into the finite element model and predict the ballistic limit of a composite laminate based on the information from quasi-static punch shear test; (ii) To understand penetration, material erosion, ballistic limit and delamination mechanisms for single and multi-site high velocity (or ballistic) impact of composite laminates; (iii) To investigate the different failure

  2. Spectroscopic classification of supernova candidates

    NASA Astrophysics Data System (ADS)

    Hodgkin, S. T.; Hall, A.; Fraser, M.; Campbell, H.; Wyrzykowski, L.; Kostrzewa-Rutkowska, Z.; Pietro, N.

    2014-09-01

    We report the spectroscopic classification of four supernovae at the 2.5m Isaac Newton Telescope on La Palma, using the Intermediate Dispersion Spectrograph and the R300V grating (3500-8000 Ang; ~6 Ang resolution).

  3. RISK FACTORS FOR NEW ONSET AND PERSISTENCE OF MULTI-SITE MUSCULOSKELETAL PAIN IN A LONGITUDINAL STUDY OF WORKERS IN CRETE

    PubMed Central

    Solidaki, Eleni; Chatzi, Leda; Bitsios, Panos; Coggon, David; Palmer, Keith T.; Kogevinas, Manolis

    2012-01-01

    Objectives To explore occupational and psychological risk factors for the incidence and persistence of multi-site musculoskeletal pain. Methods We conducted a longitudinal investigation of three occupational groups in Crete, Greece. Baseline information was obtained at interview about pain in the past year at each of six anatomical sites, and about possible risk factors for subsequent symptoms. Twelve months later, subjects were re-interviewed about pain at the same anatomical sites in the past month. Pain at two or more sites was classed as multi-site. Associations with new development and persistence of multi-site pain at follow-up were assessed by logistic regression. Results Analysis was based on 518 subjects (87% of those originally selected for study). At follow-up, multi-site pain persisted in 217 (62%) of those who had experienced it in the year before baseline, and was newly developed in 27 (17%) of those who had not. Persistence of multi-site pain was significantly related to physical loading at work, somatising tendency and beliefs about work as a cause of musculoskeletal pain, with ORs (95%CIs) for the highest relative to the lowest exposure categories of 2.3 (1.0-5.6), 2.6 (1.5-4.6) and 1.9 (1.1-3.3) respectively. Development of new multi-site pain was most strongly associated with working for ≥ 40 hours per week (OR 5.0, 95%CI 1.1-24.0). Conclusions Our findings confirm the importance of both physical loading at work and somatising tendency as risk factors for multi-site pain, and suggest that persistence of pain is also influenced by adverse beliefs about work-causation. PMID:22864252

  4. Spectroscopic Classification of PS16chs with SOAR/Goodman

    NASA Astrophysics Data System (ADS)

    Miller, J. A.; Hounsell, R. A.; Pan, Y.-C.; Foley, R. J.; Jha, S. W.; Rest, A.; Scolnic, D.

    2016-05-01

    We report the classification of PS16chs from spectroscopic observation with the Goodman spectrograph on the SOAR telescope. The observation was made on 2016 May 08 UT. We classify PS16chs as a SN Ia near maximum light at z = 0.19.

  5. Observational Aspects of Pulsating B and A Stars

    NASA Astrophysics Data System (ADS)

    Sterken, Christiaan; Kurtz, Donald W.

    2002-02-01

    In 1998 the Ministry of the Flemish Community (Department Science) allotted a research grant in the framework 'Bilateral scientific and technological cooperation' to a project entitled 'Multi-site coordinated observing of short-period variable stars' to a consortium of four astronomical institutes, viz. Vrije Universiteit Brussel (Observational Astronomy), Katholieke Universiteit Leuven (Astronomical Institute), University of Cape Town (Department of Astronomy) and South African Astronomical Observatory. The project consolidates two decades of scientific collaboration between the Flemish and South-African partners in the field of small-amplitude short-period variables (beta Cephei, delta Scuti and rapidly oscillating Ap stars) and long-period pulsating stars (gamma Dor stars). The allotted grant intended to achieve co-ordinated multi-site observing of several key objects selected among some of the most interesting pulsating variable stars observable from the southern hemisphere. The purpose of the workshop was to comply with the Government's requirement to organise one scientific conference in Flanders, evaluate the scientific outcome of the project including a discussion of logistic elements, and initiate a broader debate on the impact of government funding on the very specific discipline to which our scientific activities belong, viz. multi-site coordinated observations of stellar variability.

  6. Multisite validation of image analysis methods: assessing intra- and intersite variability

    NASA Astrophysics Data System (ADS)

    Styner, Martin A.; Charles, H. C.; Park, Jin; Gerig, Guido

    2002-05-01

    In this work, we present a unique set of 3D MRI brain data that is appropriate for testing the intra and inter-site variability of image analysis methods. A single subject was scanned two times within a 24 hour time window each at five different MR sites over a period of six weeks using GE and Phillips 1.5 T scanners. The imaging protocol included T1 weighted, Proton Density and T2 weighted images. We applied three quantitative image analysis methods and analyzed their results via the coefficients of variability (COV) and the intra correlation coefficient. The tested methods include two multi-channel tissue segmentation techniques based on an anatomically guided manual seeding and an atlas-based seeding. The third tested method was a single-channel semi-automatic segmentation of the hippocampus. The results show that the outcome of image analysis methods varies significantly for images from different sites and scanners. With the exception of total brain volume, which shows consistent low variability across all images, the COV's were clearly larger between sites than within sites. Also, the COV's between sites with different scanner types are slightly larger than between sites with the same scanner type. The presented existence of a significant inter-site variability requires adaptations in image methods to produce repeatable measurements. This is especially of importance in multi-site clinical research.

  7. Multisite Infection with Mycobacterium abscessus after Replacement of Breast Implants and Gluteal Lipofilling

    PubMed Central

    Rüegg, Eva; Cheretakis, Alexandre; Modarressi, Ali; Harbarth, Stephan; Pittet-Cuénod, Brigitte

    2015-01-01

    Introduction. Medical tourism for aesthetic surgery is popular. Nontuberculous mycobacteria (NTM) occasionally cause surgical-site infections. As NTM grow in biofilms, implantations of foreign bodies are at risk. Due to late manifestation, infections occur when patients are back home, where they must be managed properly. Case Report. A 39-year-old healthy female was referred for acute infection of the right gluteal area. Five months before, she had breast implants replacement, abdominal liposuction, and gluteal lipofilling in Mexico. Three months postoperatively, implants were removed for NTM-infection in Switzerland. Adequate antibiotic treatment was stopped after seven days for drug-related hepatitis. At entrance, gluteal puncture for bacterial analysis was performed. MRI showed large subcutaneous collection. Debridement under general anaesthesia was followed by open wound management. Total antibiotic treatment was 20 weeks. Methods. Bacterial analysis of periprosthetic and gluteal liquids included Gram-stain plus acid-fast stain, and aerobic, anaerobic and mycobacterial cultures.  Results. In periprosthetic fluid, Mycobacterium abscessus, Propionibacterium, and Staphylococcus epidermidis were identified. The same M. abscessus strain was found gluteally. The gluteal wound healed within six weeks. At ten months' follow-up, gluteal asymmetry persists for deep scarring. Conclusion. This case presents major complications of multisite aesthetic surgery. Surgical-site infections in context of medical tourism need appropriate bacteriological investigations, considering potential NTM-infections. PMID:25893122

  8. Facilitating outpatient treatment entry following detoxification for injection drug use: a multisite test of three interventions.

    PubMed

    Campbell, Barbara K; Fuller, Bret E; Lee, Eun Sul; Tillotson, Carrie; Woelfel, Tiffany; Jenkins, Lindsay; Robinson, James; Booth, Robert E; McCarty, Dennis

    2009-06-01

    A multisite, randomized trial within the National Drug Abuse Treatment Clinical Trials Network (CTN) was conducted to test 3 interventions to enhance treatment initiation following detoxification: (a) a single session, therapeutic alliance intervention (TA) added to usual treatment; (b) a 2-session, counseling and education, HIV/HCV risk reduction intervention (C&E), added to usual treatment; and (c) treatment as usual (TAU) only. Injection drug users (n=632) enrolled in residential detoxification at 8 community treatment programs were randomized to 1 of the 3 study conditions. TA participants reported entering outpatient treatment sooner and in greater numbers than TAU participants. Reported treatment entry for C&E fell between TA and TAU with no significant differences between C&E and the other conditions. There were no differences among the interventions in retention, as measured by weeks of outpatient treatment for all participants who reported treatment entry. Alliance building interventions appear to be effective in facilitating transfer from detoxification to outpatient treatment, but additional treatment engagement interventions may be necessary to improve retention. PMID:19586142

  9. Multisite mean-field theory for cold bosonic atoms in optical lattices

    NASA Astrophysics Data System (ADS)

    McIntosh, T.; Pisarski, P.; Gooding, R. J.; Zaremba, E.

    2012-07-01

    We present a detailed derivation of a multisite mean-field theory (MSMFT) used to describe the Mott-insulator to superfluid transition of bosonic atoms in optical lattices. The approach is based on partitioning the lattice into small clusters which are decoupled by means of a mean-field approximation. This approximation invokes local superfluid order parameters defined for each of the boundary sites of the cluster. The resulting MSMFT grand potential has a nontrivial topology as a function of the various order parameters. An understanding of this topology provides two different criteria for the determination of the Mott insulator superfluid phase boundaries. We apply this formalism to d-dimensional hypercubic lattices in one, two, and three dimensions and demonstrate the improvement in the estimation of the phase boundaries when MSMFT is utilized for increasingly larger clusters, with the best quantitative agreement found for d=3. The MSMFT is then used to examine a linear dimer chain in which the onsite energies within the dimer have an energy separation of Δ. This system has a complicated phase diagram within the parameter space of the model, with many distinct Mott phases separated by superfluid regions.

  10. A Multisite Study of the Prevalence of HIV With Rapid Testing in Mental Health Settings

    PubMed Central

    Blank, Michael B.; Himelhoch, Seth S.; Balaji, Alexandra B.; Metzger, David S.; Dixon, Lisa B.; Rose, Charles E.; Oraka, Emeka; Davis-Vogel, Annet; Thompson, William W.; Heffelfinger, James D.

    2014-01-01

    Objectives. We estimated HIV prevalence and risk factors among persons receiving mental health treatment in Philadelphia, Pennsylvania, and Baltimore, Maryland, January 2009 to August 2011. Methods. We used a multisite, cross-sectional design stratified by clinical setting. We tested 1061 individuals for HIV in university-based inpatient psychiatric units (n = 287), intensive case-management programs (n = 273), and community mental health centers (n = 501). Results. Fifty-one individuals (4.8%) were HIV-infected. Confirmed positive HIV tests were 5.9% (95% confidence interval [CI] = 3.7%, 9.4%) for inpatient units, 5.1% (95% CI = 3.1%, 8.5%) for intensive case-management programs, and 4.0% (95% CI = 2.6%, 6.1%) for community mental health centers. Characteristics associated with HIV included Black race, homosexual or bisexual identity, and HCV infection. Conclusions. HIV prevalence for individuals receiving mental health services was about 4 times as high as in the general population. We found a positive association between psychiatric symptom severity and HIV infection, indicating that engaging persons with mental illness in appropriate mental health treatment may be important to HIV prevention. These findings reinforce recommendations for routine HIV testing in all clinical settings to ensure that HIV-infected persons receiving mental health services are identified and referred to timely infectious disease care. PMID:24524493

  11. A reinvestigation of the multisite phosphorylation of the transcription factor c-Jun.

    PubMed

    Morton, Simon; Davis, Roger J; McLaren, Ann; Cohen, Philip

    2003-08-01

    We have used phospho-specific antibodies to re-examine the multisite phosphorylation of c-Jun in murine RAW macrophages and embryonic fibroblasts. Our results indicate that JNK isoforms are required and sufficient for the phosphorylation of Thr91 and Thr93, as well as the phosphorylation of Ser63 and Ser73, in response to LPS or anisomycin in macrophages and TNFalpha or anisomycin in fibroblasts. However, the phorbol ester (TPA) and EGF-induced phosphorylation of Ser63 and Ser73 is mediated by ERK1/ERK2, as well as JNK1/JNK2, in fibroblasts from wild-type mice and by ERK1/ERK2 alone in fibroblasts from JNK-deficient mice. The phosphorylation of Thr239 is catalysed by GSK3 and the phosphorylation of Ser243 by an as yet unidentified protein kinase. The inhibition of GSK3 is not required for the dephosphorylation of Thr239 in response to LPS, and nor is the phosphorylation of Thr91 and Thr93 required for the TPA- or EGF-induced dephosphorylation of Thr239 in fibroblasts. The agonist-induced dephosphorylation of Thr239 may involve a conformational change that exposes Thr239 to dephosphorylation and/or the activation of a Thr239 phosphatase. PMID:12881422

  12. Multisite Promiscuity in the Processing of Endogenous Substrates By Human Carboxylesterase 1

    SciTech Connect

    Bencharit, S.; Edwards, C.C.; Morton, C.L.; Howard-Williams, E.L.; Kuhn, P.; Potter, P.M.; Redinbo, M.R.; /North Carolina U. /St. Jude Children's Hosp., Memphis /SLAC, SSRL

    2007-01-16

    Human carboxylesterase 1 (hCE1) is a drug and endobiotic-processing serine hydrolase that exhibits relatively broad substrate specificity. It has been implicated in a variety of endogenous cholesterol metabolism pathways including the following apparently disparate reactions: cholesterol ester hydrolysis (CEH), fatty acyl Coenzyme A hydrolysis (FACoAH), acyl-Coenzyme A:cholesterol acyltransfer (ACAT), and fatty acyl ethyl ester synthesis (FAEES). The structural basis for the ability of hCE1 to perform these catalytic actions involving large substrates and products has remained unclear. Here we present four crystal structures of the hCE1 glycoprotein in complexes with the following endogenous substrates or substrate analogues: Coenzyme A, the fatty acid palmitate, and the bile acids cholate and taurocholate. While the active site of hCE1 was known to be promiscuous and capable of interacting with a variety of chemically distinct ligands, these structures reveal that the enzyme contains two additional ligand-binding sites and that each site also exhibits relatively non-specific ligand-binding properties. Using this multisite promiscuity, hCE1 appears structurally capable of assembling several catalytic events depending, apparently, on the physiological state of the cellular environment. These results expand our understanding of enzyme promiscuity and indicate that, in the case of hCE1, multiple non-specific sites are employed to perform distinct catalytic actions.

  13. User Satisfaction Evaluation of the EHR4CR Query Builder: A Multisite Patient Count Cohort System

    PubMed Central

    Soto-Rey, Iñaki; N'Dja, Aurèle; Cunningham, James; Newe, Axel; Trinczek, Benjamin; Lafitte, Caroline; Sedlmayr, Brita; Fritz, Fleur

    2015-01-01

    The Electronic Health Records for Clinical Research (EHR4CR) project aims to develop services and technology for the leverage reuse of Electronic Health Records with the purpose of improving the efficiency of clinical research processes. A pilot program was implemented to generate evidence of the value of using the EHR4CR platform. The user acceptance of the platform is a key success factor in driving the adoption of the EHR4CR platform; thus, it was decided to evaluate the user satisfaction. In this paper, we present the results of a user satisfaction evaluation for the EHR4CR multisite patient count cohort system. This study examined the ability of testers (n = 22 and n = 16 from 5 countries) to perform three main tasks (around 20 minutes per task), after a 30-minute period of self-training. The System Usability Scale score obtained was 55.83 (SD: 15.37), indicating a moderate user satisfaction. The responses to an additional satisfaction questionnaire were positive about the design of the interface and the required procedure to design a query. Nevertheless, the most complex of the three tasks proposed in this test was rated as difficult, indicating a need to improve the system regarding complicated queries. PMID:26539525

  14. A Multisite Randomized Effectiveness Trial of Motivational Enhancement Therapy for Spanish-Speaking Substance Users

    PubMed Central

    Carroll, Kathleen M.; Martino, Steve; Ball, Samuel A.; Nich, Charla; Frankforter, Tami; Anez, Luis M; Paris, Manuel; Suarez-Morales, Lourdes; Szapocznik, José; Miller, William R.; Rosa, Carmen; Matthews, Julie; Farentinos, Chris

    2009-01-01

    Hispanic individuals are underrepresented in clinical and research populations and often excluded from clinical trials in the US. Hence, there are few data on the effectiveness of most empirically validated therapies for Hispanic substance users. We conducted a multisite randomized trial comparing the effectiveness of three individual sessions of motivational enhancement therapy (MET) to three individual sessions of counseling as usual (CAU) on treatment retention and frequency of substance use, with all assessment and treatment sessions conducted in Spanish among 405 individuals seeking treatment for any type of current substance use. Treatment exposure was good, with 66% of participants completing all three protocol sessions. Although both interventions resulted in reductions in substance use during the 4-week therapy phase, there were no significant treatment condition by time interactions nor site by treatment condition interactions. Results suggest that the individual treatments delivered in Spanish were both attractive to and effective with this heterogeneous group of Hispanic adults, but the differential effectiveness of MET may be limited to those whose primary substance use problem is alcohol and may be fairly modest in magnitude. PMID:19803579

  15. Multisite phosphorylation of C-Nap1 releases it from Cep135 to trigger centrosome disjunction

    PubMed Central

    Hardy, Tara; Lee, Miseon; Hames, Rebecca S.; Prosser, Suzanna L.; Cheary, Donna-Marie; Samant, Mugdha D.; Schultz, Francisca; Baxter, Joanne E.; Rhee, Kunsoo; Fry, Andrew M.

    2014-01-01

    ABSTRACT During mitotic entry, centrosomes separate to establish the bipolar spindle. Delays in centrosome separation can perturb chromosome segregation and promote genetic instability. However, interphase centrosomes are physically tethered by a proteinaceous linker composed of C-Nap1 (also known as CEP250) and the filamentous protein rootletin. Linker disassembly occurs at the onset of mitosis in a process known as centrosome disjunction and is triggered by the Nek2-dependent phosphorylation of C-Nap1. However, the mechanistic consequences of C-Nap1 phosphorylation are unknown. Here, we demonstrate that Nek2 phosphorylates multiple residues within the C-terminal domain of C-Nap1 and, collectively, these phosphorylation events lead to loss of oligomerization and centrosome association. Mutations in non-phosphorylatable residues that make the domain more acidic are sufficient to release C-Nap1 from the centrosome, suggesting that it is an increase in overall negative charge that is required for this process. Importantly, phosphorylation of C-Nap1 also perturbs interaction with the core centriolar protein, Cep135, and interaction of endogenous C-Nap1 and Cep135 proteins is specifically lost in mitosis. We therefore propose that multisite phosphorylation of C-Nap1 by Nek2 perturbs both oligomerization and Cep135 interaction, and this precipitates centrosome disjunction at the onset of mitosis. PMID:24695856

  16. Evaluation of Speech-Perception Training for Hearing Aid Users: A Multisite Study in Progress.

    PubMed

    Miller, James D; Watson, Charles S; Dubno, Judy R; Leek, Marjorie R

    2015-11-01

    Following an overview of theoretical issues in speech-perception training and of previous efforts to enhance hearing aid use through training, a multisite study, designed to evaluate the efficacy of two types of computerized speech-perception training for adults who use hearing aids, is described. One training method focuses on the identification of 109 syllable constituents (45 onsets, 28 nuclei, and 36 codas) in quiet and in noise, and on the perception of words in sentences presented in various levels of noise. In a second type of training, participants listen to 6- to 7-minute narratives in noise and are asked several questions about each narrative. Two groups of listeners are trained, each using one of these types of training, performed in a laboratory setting. The training for both groups is preceded and followed by a series of speech-perception tests. Subjects listen in a sound field while wearing their hearing aids at their usual settings. The training continues over 15 to 20 visits, with subjects completing at least 30 hours of focused training with one of the two methods. The two types of training are described in detail, together with a summary of other perceptual and cognitive measures obtained from all participants. PMID:27587914

  17. The CHARA Catalog of Orbital Elements of Spectroscopic Binary Stars

    NASA Astrophysics Data System (ADS)

    Taylor, S. F.; McAlister, H. A.; Harvin, J. A.

    2003-12-01

    Optical interferometry is entering a new age with several ground-based longbaseline observatories now making observations of unprecedented resolution. Interferometers bring a new level of resolution to bear on spectroscopic binaries, enabling the full extraction of the physical parameters for the component stars with high accuracy. In the case of double-lined systems, a geometrically determined orbital parallax becomes available as well. The first step in preparing to observe spectroscopic binaries is to list them, which has not been done since the 1989 publication of the Eighth Catalogue of the Orbital Elements of Spectroscopic Binaries by Batten, et al. (1989). We present a new catalog with roughly half again as many listings as the Eighth Catalog. Angular separation predictions are made for each catalog entry. The numbers of spectroscopic binaries available for study as a function of several important observational parameters are explored, and in particular, the number of spectroscopic binaries as a function of expected separation is discussed. CHARA gratefully acknowledges the support of the National Science Foundation, the offices of the Dean of the College of Arts and Sciences, the Vice President for Research at Georgia State University, the W.M. Keck Foundation, and the David and Lucile Packard Foundation.

  18. Ground-based search for the brightest transiting planets with the Multi-site All-Sky CAmeRA: MASCARA

    NASA Astrophysics Data System (ADS)

    Snellen, Ignas A. G.; Stuik, Remko; Navarro, Ramon; Bettonvil, Felix; Kenworthy, Matthew; de Mooij, Ernst; Otten, Gilles; ter Horst, Rik; le Poole, Rudolf

    2012-09-01

    The Multi-site All-sky CAmeRA MASCARA is an instrument concept consisting of several stations across the globe, with each station containing a battery of low-cost cameras to monitor the near-entire sky at each location. Once all stations have been installed, MASCARA will be able to provide a nearly 24-hr coverage of the complete dark sky, down to magnitude 8, at sub-minute cadence. Its purpose is to find the brightest transiting exoplanet systems, expected in the V=4-8 magnitude range - currently not probed by space- or ground-based surveys. The bright/nearby transiting planet systems, which MASCARA will discover, will be the key targets for detailed planet atmosphere observations. We present studies on the initial design of a MASCARA station, including the camera housing, domes, and computer equipment, and on the photometric stability of low-cost cameras showing that a precision of 0.3-1% per hour can be readily achieved. We plan to roll out the first MASCARA station before the end of 2013. A 5-station MASCARA can within two years discover up to a dozen of the brightest transiting planet systems in the sky.

  19. Magnetospheric accretion onto the T Tauri star AA Tauri. I. Constraints from multisite spectrophotometric monitoring

    NASA Astrophysics Data System (ADS)

    Bouvier, J.; Chelli, A.; Allain, S.; Carrasco, L.; Costero, R.; Cruz-Gonzalez, I.; Dougados, C.; Fernández, M.; Martín, E. L.; Ménard, F.; Mennessier, C.; Mujica, R.; Recillas, E.; Salas, L.; Schmidt, G.; Wichmann, R.

    1999-09-01

    We have monitored the photometric, spectroscopic and polarimetric variations of the classical T Tauri star (CTTS) AA Tau over a period of a month. The light curve consists of more than 260 measurements in each of the B and V-bands over a continuous time period of 30 days and more than 180 measurements in the R and I-bands. This provides unprecedented detail of the photometric variations of a CTTS on timescales ranging from hours to weeks. We find that AA Tau's light curve is quite unlike that of most other CTTS. It exhibits a roughly constant brightness level, interrupted by quasi-cyclic fading episodes with an amplitude of 1.4 mag in BVRI filters. We interpret this behaviour as resulting from quasi-periodic occultations of the stellar photosphere by opaque circumstellar material. The interpretation derives from the lack of significant color variations associated with the fading of the system and is strengthened by the higher polarization level measured when the system is faint. We argue that the occultations are produced by a warp in AA Tau's inner disk which presumably results from the dynamical interaction between the disk and the stellar magnetosphere. We present a model that accounts for the observations quite naturally if we assume that the stellar magnetosphere is a large-scale dipole tilted onto the stellar rotational axis which disrupts the disk at the corotation radius. We derive the geometrical properties of AA Tau's accretion zone in the framework of this model and constrain the location of veiling and Balmer line emitting regions. Although AA Tau's light curve is atypical, the constraints derived here on the structure of its accretion zone may apply as well to other CTTS. It is probably only because AA Tau is seen at a peculiar inclination, close to edge-on, that occultations are conspicuous and its photometric behaviour so clearly reveals this phenomenon. Based on observations obtained at Haute-Provence and Pic du Midi Observatories (France), San

  20. The Gaia-ESO Public Spectroscopic Survey

    NASA Astrophysics Data System (ADS)

    Gilmore, G.; Randich, S.; Asplund, M.; Binney, J.; Bonifacio, P.; Drew, J.; Feltzing, S.; Ferguson, A.; Jeffries, R.; Micela, G.; Negueruela, I.; Prusti, T.; Rix, H.-W.; Vallenari, A.; Alfaro, E.; Allende-Prieto, C.; Babusiaux, C.; Bensby, T.; Blomme, R.; Bragaglia, A.; Flaccomio, E.; François, P.; Irwin, M.; Koposov, S.; Korn, A.; Lanzafame, A.; Pancino, E.; Paunzen, E.; Recio-Blanco, A.; Sacco, G.; Smiljanic, R.; Van Eck, S.; Walton, N.; Aden, D.; Aerts, C.; Affer, L.; Alcala, J.-M.; Altavilla, G.; Alves, J.; Antoja, T.; Arenou, F.; Argiroffi, C.; Asensio Ramos, A.; Bailer-Jones, C.; Balaguer-Nunez, L.; Bayo, A.; Barbuy, B.; Barisevicius, G.; Barrado y Navascues, D.; Battistini, C.; Bellas Velidis, I.; Bellazzini, M.; Belokurov, V.; Bergemann, M.; Bertelli, G.; Biazzo, K.; Bienayme, O.; Bland-Hawthorn, J.; Boeche, C.; Bonito, S.; Boudreault, S.; Bouvier, J.; Brandao, I.; Brown, A.; de Bruijne, J.; Burleigh, M.; Caballero, J.; Caffau, E.; Calura, F.; Capuzzo-Dolcetta, R.; Caramazza, M.; Carraro, G.; Casagrande, L.; Casewell, S.; Chapman, S.; Chiappini, C.; Chorniy, Y.; Christlieb, N.; Cignoni, M.; Cocozza, G.; Colless, M.; Collet, R.; Collins, M.; Correnti, M.; Covino, E.; Crnojevic, D.; Cropper, M.; Cunha, M.; Damiani, F.; David, M.; Delgado, A.; Duffau, S.; Edvardsson, B.; Eldridge, J.; Enke, H.; Eriksson, K.; Evans, N. W.; Eyer, L.; Famaey, B.; Fellhauer, M.; Ferreras, I.; Figueras, F.; Fiorentino, G.; Flynn, C.; Folha, D.; Franciosini, E.; Frasca, A.; Freeman, K.; Fremat, Y.; Friel, E.; Gaensicke, B.; Gameiro, J.; Garzon, F.; Geier, S.; Geisler, D.; Gerhard, O.; Gibson, B.; Gomboc, A.; Gomez, A.; Gonzalez-Fernandez, C.; Gonzalez Hernandez, J.; Gosset, E.; Grebel, E.; Greimel, R.; Groenewegen, M.; Grundahl, F.; Guarcello, M.; Gustafsson, B.; Hadrava, P.; Hatzidimitriou, D.; Hambly, N.; Hammersley, P.; Hansen, C.; Haywood, M.; Heber, U.; Heiter, U.; Held, E.; Helmi, A.; Hensler, G.; Herrero, A.; Hill, V.; Hodgkin, S.; Huelamo, N.; Huxor, A.; Ibata, R.; Jackson, R.; de Jong, R.; Jonker, P.; Jordan, S.; Jordi, C.; Jorissen, A.; Katz, D.; Kawata, D.; Keller, S.; Kharchenko, N.; Klement, R.; Klutsch, A.; Knude, J.; Koch, A.; Kochukhov, O.; Kontizas, M.; Koubsky, P.; Lallement, R.; de Laverny, P.; van Leeuwen, F.; Lemasle, B.; Lewis, G.; Lind, K.; Lindstrom, H. P. E.; Lobel, A.; Lopez Santiago, J.; Lucas, P.; Ludwig, H.; Lueftinger, T.; Magrini, L.; Maiz Apellaniz, J.; Maldonado, J.; Marconi, G.; Marino, A.; Martayan, C.; Martinez-Valpuesta, I.; Matijevic, G.; McMahon, R.; Messina, S.; Meyer, M.; Miglio, A.; Mikolaitis, S.; Minchev, I.; Minniti, D.; Moitinho, A.; Momany, Y.; Monaco, L.; Montalto, M.; Monteiro, M. J.; Monier, R.; Montes, D.; Mora, A.; Moraux, E.; Morel, T.; Mowlavi, N.; Mucciarelli, A.; Munari, U.; Napiwotzki, R.; Nardetto, N.; Naylor, T.; Naze, Y.; Nelemans, G.; Okamoto, S.; Ortolani, S.; Pace, G.; Palla, F.; Palous, J.; Parker, R.; Penarrubia, J.; Pillitteri, I.; Piotto, G.; Posbic, H.; Prisinzano, L.; Puzeras, E.; Quirrenbach, A.; Ragaini, S.; Read, J.; Read, M.; Reyle, C.; De Ridder, J.; Robichon, N.; Robin, A.; Roeser, S.; Romano, D.; Royer, F.; Ruchti, G.; Ruzicka, A.; Ryan, S.; Ryde, N.; Santos, N.; Sanz Forcada, J.; Sarro Baro, L. M.; Sbordone, L.; Schilbach, E.; Schmeja, S.; Schnurr, O.; Schoenrich, R.; Scholz, R.-D.; Seabroke, G.; Sharma, S.; De Silva, G.; Smith, M.; Solano, E.; Sordo, R.; Soubiran, C.; Sousa, S.; Spagna, A.; Steffen, M.; Steinmetz, M.; Stelzer, B.; Stempels, E.; Tabernero, H.; Tautvaisiene, G.; Thevenin, F.; Torra, J.; Tosi, M.; Tolstoy, E.; Turon, C.; Walker, M.; Wambsganss, J.; Worley, C.; Venn, K.; Vink, J.; Wyse, R.; Zaggia, S.; Zeilinger, W.; Zoccali, M.; Zorec, J.; Zucker, D.; Zwitter, T.; Gaia-ESO Survey Team

    2012-03-01

    The Gaia-ESO Public Spectroscopic Survey has begun and will obtain high quality spectroscopy of some 100000 Milky Way stars, in the field and in open clusters, down to magnitude 19, systematically covering all the major components of the Milky Way. This survey will provide the first homogeneous overview of the distributions of kinematics and chemical element abundances in the Galaxy. The motivation, organisation and implementation of the Gaia-ESO Survey are described, emphasising the complementarity with the ESA Gaia mission. Spectra from the very first observing run of the survey are presented.

  1. Addressing spectroscopic quality of covariant density functional theory

    NASA Astrophysics Data System (ADS)

    Afanasjev, A. V.

    2015-03-01

    The spectroscopic quality of covariant density functional theory has been accessed by analyzing the accuracy and theoretical uncertainties in the description of spectroscopic observables. Such analysis is first presented for the energies of the single-particle states in spherical and deformed nuclei. It is also shown that the inclusion of particle-vibration coupling improves the description of the energies of predominantly single-particle states in medium and heavy-mass spherical nuclei. However, the remaining differences between theory and experiment clearly indicate missing physics and missing terms in covariant energy density functionals. The uncertainties in the predictions of the position of two-neutron drip line sensitively depend on the uncertainties in the prediction of the energies of the single-particle states. On the other hand, many spectroscopic observables in well deformed nuclei at ground state and finite spin only weakly depend on the choice of covariant energy density functional.

  2. Update on New Spectroscopic Orbits of Potential Interferometric Binaries

    NASA Astrophysics Data System (ADS)

    Fekel, Francis C.; Williamson, Michael; Muterspaugh, Matthew; Tomkin, Jocelyn

    2015-08-01

    We update the status of a program to obtain radial velocities from high-resolution, red-wavelength spectra to improve the orbits of bright known spectroscopic binaries that are potential targets of ground-based interferometers. Of the 51 systems that have been extensively observed in this project, four or 8% have been found spectroscopically to have a long period companion, making the systems at least triple. Most of the 25 systems still to be published are solar-type stars or late-type giants, and we have detected the secondary of nine former single-lined spectroscopic binaries. The combination of spectroscopy and astrometry from interferometric observations will result in three-dimensional orbits and will produce systems with mass uncertainties less than 1% and well determined distances. Orbital inclinations for some of our stars can also be obtained with astrometry from the GAIA mission.

  3. Soft tissue imaging with photon counting spectroscopic CT

    NASA Astrophysics Data System (ADS)

    Shikhaliev, Polad M.

    2015-03-01

    The purpose of this work was experimental investigation of photon counting spectroscopic CT (PCS-CT) imaging of anatomical soft tissue with clinically relevant size. The imaging experiments were performed using a spectroscopic CT system based on CdZnTe photon counting detector with two rows of pixels, 256 pixels in each row, 1  ×  1 mm2 pixel size, and 25.6 cm detector length. The detector could split the x-ray energy spectrum to 5 regions (energy bins), and acquire 5 multi-energy (spectroscopic) CT images in a single CT scan. A sample of round shaped anatomical soft tissue of 14 cm diameter including lean and fat was used for imaging. To avoid the negative effect of anatomical noise on quantitative analysis, a spectroscopic CT phantom with tissue equivalent solid materials was used. The images were acquired at 60, 90, and 120 kVp tube voltages, and spectroscopic image series were acquired with 3 and 5 energy bins. Spectroscopic CT numbers were introduced and used to evaluate an energy selective image series. The anatomical soft tissue with 14 cm diameter was visualized with good quality and without substantial artifacts by the photon counting spectroscopic CT system. The effects of the energy bin crosstalk on spectroscopic CT numbers were quantified and analyzed. The single and double slice PCS-CT images were acquired and compared. Several new findings were observed, including the effect of soft tissue non-uniformity on image artifacts, unique status of highest energy bin, and material dependent visualization in spectroscopic image series. Fat-lean decomposition was performed using dual energy subtraction and threshold segmentation methods, and compared. Using K-edge filtered x-rays improved fat-lean decomposition as compared to conventional x-rays. Several new and important aspects of the PCS-CT were investigated. These include imaging soft tissue with clinically relevant size, single- and double-slice PCS-CT imaging, using spectroscopic CT

  4. Soft tissue imaging with photon counting spectroscopic CT.

    PubMed

    Shikhaliev, Polad M

    2015-03-21

    The purpose of this work was experimental investigation of photon counting spectroscopic CT (PCS-CT) imaging of anatomical soft tissue with clinically relevant size. The imaging experiments were performed using a spectroscopic CT system based on CdZnTe photon counting detector with two rows of pixels, 256 pixels in each row, 1  ×  1 mm(2) pixel size, and 25.6 cm detector length. The detector could split the x-ray energy spectrum to 5 regions (energy bins), and acquire 5 multi-energy (spectroscopic) CT images in a single CT scan. A sample of round shaped anatomical soft tissue of 14 cm diameter including lean and fat was used for imaging. To avoid the negative effect of anatomical noise on quantitative analysis, a spectroscopic CT phantom with tissue equivalent solid materials was used. The images were acquired at 60, 90, and 120 kVp tube voltages, and spectroscopic image series were acquired with 3 and 5 energy bins. Spectroscopic CT numbers were introduced and used to evaluate an energy selective image series. The anatomical soft tissue with 14 cm diameter was visualized with good quality and without substantial artifacts by the photon counting spectroscopic CT system. The effects of the energy bin crosstalk on spectroscopic CT numbers were quantified and analyzed. The single and double slice PCS-CT images were acquired and compared. Several new findings were observed, including the effect of soft tissue non-uniformity on image artifacts, unique status of highest energy bin, and material dependent visualization in spectroscopic image series. Fat-lean decomposition was performed using dual energy subtraction and threshold segmentation methods, and compared. Using K-edge filtered x-rays improved fat-lean decomposition as compared to conventional x-rays. Several new and important aspects of the PCS-CT were investigated. These include imaging soft tissue with clinically relevant size, single- and double-slice PCS-CT imaging, using spectroscopic CT

  5. Control of Pteridium aquilinum: Meta-analysis of a Multi-site Study in the UK

    PubMed Central

    Stewart, Gavin; Cox, Emma; Le Duc, Mike; Pakeman, Robin; Pullin, Andrew; Marrs, Rob

    2008-01-01

    Background and Aims A great deal of money is spent controlling invasive weeds as part of international and national policies. It is essential that the funded treatments work across the region in which the policies operate. We argue that experiments across multiple sites are required to validate these programs as results from single sites may be misleading. Here, the control of Pteridium aquilinum (bracken) is used as a test example to address the following four questions. (1) Does the effectiveness of P. aquilinum-control treatments vary across sites? (2) Is the best treatment identified in previous research (cutting twice per year) consistent at all sites, and if not why not? (3) Is treatment performance related to P. aquilinum rhizome mass, litter cover or litter depth at the various sites? (4) Does successful P. aquilinum control influence species richness? Methods Pteridium aquilinum‐control treatments were monitored for 10 years using six replicated experiments and analysed using meta-analysis. Meta-regressions were used to explore heterogeneity between sites. Key Results The effectiveness of treatments varied between sites depending on the measure used to assess P. aquilinum performance. In general, cutting twice per year was the most successful treatment but on some sites other, less expensive treatments were as good. The effectiveness of treatments at different sites was not related to rhizome mass, but the effectiveness of most applied treatments were inversely related to post-control litter. Effective treatment was also associated with high species richness. Conclusions It is concluded that successful development of national weed control programs requires multi-site experimental approaches. Here, meta-analyses demonstrate that variation in effectiveness between sites could be explained in part by pre-specified variables. Reliance on data from a single site for policy formulation is therefore clearly dangerous. PMID:18337356

  6. Multisite stochastic weather generation using cluster analysis and k-nearest neighbor time series resampling

    NASA Astrophysics Data System (ADS)

    Caraway, Nina Marie; McCreight, James Lucian; Rajagopalan, Balaji

    2014-01-01

    We offer a multisite stochastic weather generator which is an enhancement to the traditional K-nearest neighbor resampling approach. The proposed weather generator consists of three main components: (i) Clustering of spatial locations into homogeneous regions based on a selected attribute (precipitation), (ii) Markov transition probabilities (either on individual clusters or) over all eight wet/dry states of the three-cluster system to model the spatial precipitation occurrence, and (iii) the traditional K-NN weather generator applied to each cluster-averaged weather time series to generate weather sequences at all the desired locations. The weather generator is also adapted to conditional simulation based on seasonal forecasts involving modification of the third component. We demonstrate the utility of this approach by simulating daily weather sequences at 66 locations in the 25,000 sq. mile San Juan River watershed, a tributary of the Colorado River, USA. As the classic K-NN approach involves sampling from a domain-averaged feature vector, all daily weather is simulated across all locations simultaneously. While this preserves the joint statistics, it tends to be biased to the extremes on any given day. Our cluster-based approach offers the ability to account for regional persistence and spatial non-stationarities. In our comparison of the methods, the cluster-based approach demonstrates some improvement over the classic approach, particularly when modeling winter precipitation, reproducing spells, and in dry years. While this particular application shows only marginal improvement, we offer cluster-based resampling as a novel methodological contribution.

  7. Electronic Cigarette Marketing Online: a Multi-Site, Multi-Product Comparison

    PubMed Central

    Sidhu, Anupreet K; Valente, Thomas W

    2015-01-01

    Background Electronic cigarette awareness and use has been increasing rapidly. E-cigarette brands have utilized social networking sites to promote their products, as the growth of the e-cigarette industry has paralleled that of Web 2.0. These online platforms are cost-effective and have unique technological features and user demographics that can be attractive for selective marketing. The popularity of multiple sites also poses a risk of exposure to social networks where e-cigarette brands might not have a presence. Objective To examine the marketing strategies of leading e-cigarette brands on multiple social networking sites, and to identify how affordances of the digital media are used to their advantage. Secondary analyses include determining if any brands are benefitting from site demographics, and exploring cross-site diffusion of marketing content through multi-site users. Methods We collected data from two e-cigarette brands from four social networking sites over approximately 2.5 years. Content analysis is used to search for themes, population targeting, marketing strategies, and cross-site spread of messages. Results Twitter appeared to be the most frequently used social networking site for interacting directly with product users. Facebook supported informational broadcasts, such as announcements regarding political legislation. E-cigarette brands also differed in their approaches to their users, from informal conversations to direct product marketing. Conclusions E-cigarette makers use different strategies to market their product and engage their users. There was no evidence of direct targeting of vulnerable populations, but the affordances of the different sites are exploited to best broadcast context-specific messages. We developed a viable method to study cross-site diffusion, although additional refinement is needed to account for how different types of digital media are used. PMID:27227129

  8. Extraction and Characterization of Essential Discharge Patterns from Multisite Recordings of Spiking Ongoing Activity

    PubMed Central

    Storchi, Riccardo; Biella, Gabriele E. M.; Liberati, Diego; Baselli, Giuseppe

    2009-01-01

    powerful multiscale approach linking population oscillations with multisite discharge patterns. PMID:19173006

  9. Crack Growth Prediction Methodology for Multi-Site Damage: Layered Analysis and Growth During Plasticity

    NASA Technical Reports Server (NTRS)

    James, Mark Anthony

    1999-01-01

    A finite element program has been developed to perform quasi-static, elastic-plastic crack growth simulations. The model provides a general framework for mixed-mode I/II elastic-plastic fracture analysis using small strain assumptions and plane stress, plane strain, and axisymmetric finite elements. Cracks are modeled explicitly in the mesh. As the cracks propagate, automatic remeshing algorithms delete the mesh local to the crack tip, extend the crack, and build a new mesh around the new tip. State variable mapping algorithms transfer stresses and displacements from the old mesh to the new mesh. The von Mises material model is implemented in the context of a non-linear Newton solution scheme. The fracture criterion is the critical crack tip opening displacement, and crack direction is predicted by the maximum tensile stress criterion at the crack tip. The implementation can accommodate multiple curving and interacting cracks. An additional fracture algorithm based on nodal release can be used to simulate fracture along a horizontal plane of symmetry. A core of plane strain elements can be used with the nodal release algorithm to simulate the triaxial state of stress near the crack tip. Verification and validation studies compare analysis results with experimental data and published three-dimensional analysis results. Fracture predictions using nodal release for compact tension, middle-crack tension, and multi-site damage test specimens produced accurate results for residual strength and link-up loads. Curving crack predictions using remeshing/mapping were compared with experimental data for an Arcan mixed-mode specimen. Loading angles from 0 degrees to 90 degrees were analyzed. The maximum tensile stress criterion was able to predict the crack direction and path for all loading angles in which the material failed in tension. Residual strength was also accurately predicted for these cases.

  10. Reliability of neuroanatomical measurements in a multisite longitudinal study of youth at risk for psychosis.

    PubMed

    Cannon, Tyrone D; Sun, Frank; McEwen, Sarah Jacobson; Papademetris, Xenophon; He, George; van Erp, Theo G M; Jacobson, Aron; Bearden, Carrie E; Walker, Elaine; Hu, Xiaoping; Zhou, Lei; Seidman, Larry J; Thermenos, Heidi W; Cornblatt, Barbara; Olvet, Doreen M; Perkins, Diana; Belger, Aysenil; Cadenhead, Kristin; Tsuang, Ming; Mirzakhanian, Heline; Addington, Jean; Frayne, Richard; Woods, Scott W; McGlashan, Thomas H; Constable, R Todd; Qiu, Maolin; Mathalon, Daniel H; Thompson, Paul; Toga, Arthur W

    2014-05-01

    Multisite longitudinal neuroimaging designs are used to identify differential brain structural change associated with onset or progression of disease. The reliability of neuroanatomical measurements over time and across sites is a crucial aspect of power in such studies. Prior work has found that while within-site reliabilities of neuroanatomical measurements are excellent, between-site reliability is generally more modest. Factors that may increase between-site reliability include standardization of scanner platform and sequence parameters and correction for between-scanner variations in gradient nonlinearities. Factors that may improve both between- and within-site reliability include use of registration algorithms that account for individual differences in cortical patterning and shape. In this study 8 healthy volunteers were scanned twice on successive days at 8 sites participating in the North American Prodrome Longitudinal Study (NAPLS). All sites employed 3 Tesla scanners and standardized acquisition parameters. Site accounted for 2 to 30% of the total variance in neuroanatomical measurements. However, site-related variations were trivial (<1%) among sites using the same scanner model and 12-channel coil or when correcting for between-scanner differences in gradient nonlinearity and scaling. Adjusting for individual differences in sulcal-gyral geometries yielded measurements with greater reliabilities than those obtained using an automated approach. Neuroimaging can be performed across multiple sites at the same level of reliability as at a single site, achieving within- and between-site reliabilities of 0.95 or greater for gray matter density in the majority of voxels in the prefrontal and temporal cortical surfaces as well as for the volumes of most subcortical structures. PMID:23982962

  11. Multisite Comparison of High-Sensitivity Multiplex Cytokine Assays▿†

    PubMed Central

    Breen, Elizabeth Crabb; Reynolds, Sandra M.; Cox, Christopher; Jacobson, Lisa P.; Magpantay, Larry; Mulder, Candice B.; Dibben, Oliver; Margolick, Joseph B.; Bream, Jay H.; Sambrano, Elise; Martínez-Maza, Otoniel; Sinclair, Elizabeth; Borrow, Persephone; Landay, Alan L.; Rinaldo, Charles R.; Norris, Philip J.

    2011-01-01

    The concentrations of cytokines in human serum and plasma can provide valuable information about in vivo immune status, but low concentrations often require high-sensitivity assays to permit detection. The recent development of multiplex assays, which can measure multiple cytokines in one small sample, holds great promise, especially for studies in which limited volumes of stored serum or plasma are available. Four high-sensitivity cytokine multiplex assays on a Luminex (Bio-Rad, BioSource, Linco) or electrochemiluminescence (Meso Scale Discovery) platform were evaluated for their ability to detect circulating concentrations of 13 cytokines, as well as for laboratory and lot variability. Assays were performed in six different laboratories utilizing archived serum from HIV-uninfected and -infected subjects from the Multicenter AIDS Cohort Study (MACS) and the Women's Interagency HIV Study (WIHS) and commercial plasma samples spanning initial HIV viremia. In a majority of serum samples, interleukin-6 (IL-6), IL-8, IL-10, and tumor necrosis factor alpha were detectable with at least three kits, while IL-1β was clearly detected with only one kit. No single multiplex panel detected all cytokines, and there were highly significant differences (P < 0.001) between laboratories and/or lots with all kits. Nevertheless, the kits generally detected similar patterns of cytokine perturbation during primary HIV viremia. This multisite comparison suggests that current multiplex assays vary in their ability to measure serum and/or plasma concentrations of cytokines and may not be sufficiently reproducible for repeated determinations over a long-term study or in multiple laboratories but may be useful for longitudinal studies in which relative, rather than absolute, changes in cytokines are important. PMID:21697338

  12. Differential regulation of a CLC anion channel by SPAK kinase ortholog-mediated multisite phosphorylation

    PubMed Central

    Miyazaki, Hiroaki

    2012-01-01

    Shrinkage-induced inhibition of the Caenorhabditis elegans cell volume and cell cycle-dependent CLC anion channel CLH-3b occurs by concomitant phosphorylation of S742 and S747, which are located on a 175 amino acid linker domain between cystathionine-β-synthase 1 (CBS1) and CBS2. Phosphorylation is mediated by the SPAK kinase homolog GCK-3 and is mimicked by substituting serine residues with glutamate. Type 1 serine/threonine protein phosphatases mediate swelling-induced channel dephosphorylation. S742E/S747E double mutant channels are constitutively inactive and cannot be activated by cell swelling. S742E and S747E mutant channels were fully active in the absence of GCK-3 and were inactive when coexpressed with the kinase. Both channels responded to cell volume changes. However, the S747E mutant channel activated and inactivated in response to cell swelling and shrinkage, respectively, much more slowly than either wild-type or S742E mutant channels. Slower activation and inactivation of S747E was not due to altered rates of dephosphorylation or dephosphorylation-dependent conformational changes. GCK-3 binds to the 175 amino acid inter-CBS linker domain. Coexpression of wild-type CLH-3b and GCK-3 with either wild-type or S742E linkers gave rise to similar channel activity and regulation. In contrast, coexpression with the S747E linker greatly enhanced basal channel activity and increased the rate of shrinkage-induced channel inactivation. Our findings suggest the intriguing possibility that the phosphorylation state of S742 in S747E mutant channels modulates GCK-3/channel interaction and hence channel phosphorylation. These results provide a foundation for further detailed studies of the role of multisite phosphorylation in regulating CLH-3b and GCK-3 activity. PMID:22357738

  13. EPSILON AURIGAE: AN IMPROVED SPECTROSCOPIC ORBITAL SOLUTION

    SciTech Connect

    Stefanik, Robert P.; Torres, Guillermo; Lovegrove, Justin; Latham, David W.; Zajac, Joseph; Pera, Vivian E.; Mazeh, Tsevi

    2010-03-15

    A rare eclipse of the mysterious object {epsilon} Aurigae will occur in 2009-2011. We report an updated single-lined spectroscopic solution for the orbit of the primary star based on 20 years of monitoring at the CfA, combined with historical velocity observations dating back to 1897. There are 518 new CfA observations obtained between 1989 and 2009. Two solutions are presented. One uses the velocities outside the eclipse phases together with mid-times of previous eclipses, from photometry dating back to 1842, which provide the strongest constraint on the ephemeris. This yields a period of 9896.0 {+-} 1.6 days (27.0938 {+-} 0.0044 years) with a velocity semi-amplitude of 13.84 {+-} 0.23 km s{sup -1} and an eccentricity of 0.227 {+-} 0.011. The middle of the current ongoing eclipse predicted by this combined fit is JD 2,455,413.8 {+-} 4.8, corresponding to 2010 August 5. If we use only the radial velocities, we find that the predicted middle of the current eclipse is nine months earlier. This would imply that the gravitating companion is not the same as the eclipsing object. Alternatively, the purely spectroscopic solution may be biased by perturbations in the velocities due to the short-period oscillations of the supergiant.

  14. Synergies between spectroscopic and asteroseismic surveys

    NASA Astrophysics Data System (ADS)

    Fu, Jianning; De Cat, Peter; Ren, An-Bing; Yang, Xiao-Hu; Catanzaro, Giovanni; Corbally, Christopher J.; Frasca, Antonio; Gray, Richard O.; Cecylia Molenda-Zakowicz, Joanna; Shi, Jian-Rong; Ali, Luo; Zhang, Haotong

    2015-08-01

    The NASA Kepler satellite has provided unprecedented high duty-cycle, high-precision light curves for a large number of stars by continuously monitoring a field of view in Cygnus-Lyra region, leading to great progress in both discovering exoplanets and characterizing planet-hosting stars by means of asteroseismic methods. The asteroseismic survey allows the investigation of stars covering the whole H-R diagram. However, the low precision of effective temperatures and surface gravities in the KIC10 catalogue and the lack of information on chemical composition, metallicity and rotation rate prevent asteroseismic modeling, requiring spectroscopic observations for thousands of asteroseismic targets in the Kepler field in a homogeneous way.In 2010, we initiated the LAMOST-Kepler project which aimed at collecting low-resolution spectra for as many objects from the KIC10 catalogue as possible, with the Large Sky Area Multi-Object Fiber Spectroscopic Telescope (LAMOST), a 4-m telescope equipped with 4,000 optical fibers. The first round of observations has been completed in fall 2014, covering all the 14 sub-fields at least once, resulting in more than 100,000 low-resolution spectra. The stellar atmospheric parameters are then derived and the results have been confirmed to be consistent with those reported in the literature based on high-resolution spectroscopy.

  15. sick: The Spectroscopic Inference Crank

    NASA Astrophysics Data System (ADS)

    Casey, Andrew R.

    2016-03-01

    There exists an inordinate amount of spectral data in both public and private astronomical archives that remain severely under-utilized. The lack of reliable open-source tools for analyzing large volumes of spectra contributes to this situation, which is poised to worsen as large surveys successively release orders of magnitude more spectra. In this article I introduce sick, the spectroscopic inference crank, a flexible and fast Bayesian tool for inferring astrophysical parameters from spectra. sick is agnostic to the wavelength coverage, resolving power, or general data format, allowing any user to easily construct a generative model for their data, regardless of its source. sick can be used to provide a nearest-neighbor estimate of model parameters, a numerically optimized point estimate, or full Markov Chain Monte Carlo sampling of the posterior probability distributions. This generality empowers any astronomer to capitalize on the plethora of published synthetic and observed spectra, and make precise inferences for a host of astrophysical (and nuisance) quantities. Model intensities can be reliably approximated from existing grids of synthetic or observed spectra using linear multi-dimensional interpolation, or a Cannon-based model. Additional phenomena that transform the data (e.g., redshift, rotational broadening, continuum, spectral resolution) are incorporated as free parameters and can be marginalized away. Outlier pixels (e.g., cosmic rays or poorly modeled regimes) can be treated with a Gaussian mixture model, and a noise model is included to account for systematically underestimated variance. Combining these phenomena into a scalar-justified, quantitative model permits precise inferences with credible uncertainties on noisy data. I describe the common model features, the implementation details, and the default behavior, which is balanced to be suitable for most astronomical applications. Using a forward model on low-resolution, high signal

  16. Spectroscopic Classifications of Optical Transients with Mayall/KOSMOS

    NASA Astrophysics Data System (ADS)

    Pan, Y.-C.; Foley, R. J.; Jha, S. W.; Rest, A.; Scolnic, D.

    2016-06-01

    We report the following classifications of optical transients from spectroscopic observations with KOSMOS on the KPNO Mayall 4-m telescope. Targets were supplied by the Pan-STARRS Survey for Transients (PSST), All-Sky Automated Survey for Supernovae (ASAS-SN) and MASTER.

  17. Spectroscopic Classifications of Optical Transients with Mayall/KOSMOS

    NASA Astrophysics Data System (ADS)

    Pan, Y.-C.; Downing, S.; Foley, R. J.; Jha, S. W.; Rest, A.; Scolnic, D.

    2016-01-01

    We report the following classifications of optical transients from spectroscopic observations with the KOSMOS on the Mayall telescope. Targets were supplied by the All-Sky Automated Survey for Supernovae (ASAS-SN), Catalina Real-Time Transient Survey (CRTS) and the CBAT Transient Object Followup Reports.

  18. Eta Car's spectroscopic event begins to differ from 2009

    NASA Astrophysics Data System (ADS)

    Davidson, Kris; Mehner, Andrea; Humphreys, Roberta; Ishibash, K.; Martin, J. C.

    2014-08-01

    The middle of eta Car's 2014.6 spectroscopic event (periastron passage) occurred in mid-August (ATEL #6334, #6336, #6357, #6368, #6380). HST/STIS observations on July 13, July 30, and August 15 strongly suggest that the exotic He II 4687 emission is reappearing sooner than in the 2009.1 event.

  19. Optical Spectroscopic Diagnostics Of Dusty Plasma In RF Discharge

    SciTech Connect

    Orazbayev, S. A.; Jumagulov, M. N.; Dosbolayev, M. K.; Silamiya, M.; Ramazanov, T. S.; Boufendi, L.

    2011-11-29

    The parameters of the buffer plasma containing dust particles were measured by means of spectroscopic methods. The change in the emission spectrum of the buffer plasma with addition of dust was observed. It seems to relate to changing in temperature and number density of electrons due to the influence of dusts.

  20. Spectroscopic Classifications of Optical Transients with Mayall/KOSMOS

    NASA Astrophysics Data System (ADS)

    Pan, Y.-C.; Kilpatrick, C. D.; Siebert, M. R.; Foley, R. J.; Jha, S. W.; Rest, A.; Scolnic, D.

    2016-08-01

    We report the following classifications of optical transients from spectroscopic observations with KOSMOS on the KPNO Mayall 4-m telescope. Targets were supplied by the Pan-STARRS Survey for Transients (PSST) and the All-Sky Automated Survey for Supernovae (ASAS-SN).

  1. Spectroscopic Classifications of Optical Transients with SOAR/Goodman

    NASA Astrophysics Data System (ADS)

    Miller, J. A.; Hounsell, R. A.; Pan, Y.-C.; Kilpatrick, C. D.; Foley, R. J.; Jha, S. W.; Rest, A.; Scolnic, D.

    2016-08-01

    We report a classification of optical transients from spectroscopic observations with the Goodman spectrograph on the SOAR telescope. Targets were supplied by the All-Sky Automated Survey for Supernovae (ASAS-SN) and the Pan-STARRS Survey for Transients (PSST).

  2. Spectroscopic Classification of ASASSN-16bx and ASASSN-16cy

    NASA Astrophysics Data System (ADS)

    Frank, S.; Prieto, J. L.; Stanek, K. Z.

    2016-03-01

    We report optical spectroscopic observations of ASASSN-16bx (ATel #8712) and ASASSN-16cy (ATel #8801) obtained by S. Frank on UT 2016 March 14-15 with OSMOS (range 398-686 nm) mounted on the MDM 2.4m telescope at KPNO.

  3. A survey of third components in spectroscopic and eclipsing systems

    NASA Astrophysics Data System (ADS)

    Herczeg, T. J.

    1988-03-01

    A magnitude-limited (V = 6.8) survey of systems found in the Seventh Catalogue of Spectroscopic Binaries (Batten et al., 1978) is used to investigate internally stable triple systems of the type ab-c. Emphasis is placed on systems where the close pair is a spectroscopic or eclipsing binary with orbital dimensions of the order of 1-2 AU or less. With allowance for observational bias, the ratio of double to multiple systems is found to approach 1:1. Multiplicities in the W UMa system and in cataclysmic variables are also considered.

  4. Spectroscopic study of sprites

    NASA Astrophysics Data System (ADS)

    Kanmae, Takeshi

    Optical emissions from sprites--large electric discharges in the mesosphere caused by intense lightning strokes--have been studied for decades. Studies have identified that sprite emissions are primarily composed of molecular band emissions of nitrogen and notably identified the near ultraviolet and blue emission from the N2+ First Negative system, which provided direct evidence of ionization in sprites. This implies that further evidence of the ionization may be provided by the visible and near infrared emission from the N2+ Meinel system, which is more accessible from ground-based platforms, though anticipated strong quenching in the mesosphere and below have made the presence of the emission somewhat controversial. To investigate the presence of the Meinel emission along the vertical extent of sprites, we made ground-based spectral observations in 2005. The observed spectra were mainly composed of the N2 First Positive system, and no or little indication of the Meinel bands were found. This study suggests that the quenching is indeed severe at sprite altitude, and it is difficult to study the ionization process in sprites via the Meinel emission. In addition, the data allowed us to investigate details of the First Positive emission from sprites. The observed First Positive spectra showed that the vibrational distribution of the upper state varies along the vertical extent of sprites, which is in agreement with previous reports, and furthermore this study indicates that the variation is associated with altitude, implying that collisional energy transfer processes play roles in exciting the First Positive emission, particularly at lower altitudes. Recent high-speed imaging observations have revealed the very dynamic nature of sprites: they develop within a few to 10 ms in forms of streamers and columnar glows. The underlying electron energies in these features have been inferred from their emissions in previous measurements, but they lacked either sufficient

  5. ON THE SPECTROSCOPIC CLASSES OF NOVAE IN M33

    SciTech Connect

    Shafter, A. W.; Darnley, M. J.; Bode, M. F.; Ciardullo, R.

    2012-06-20

    We report the initial results from an ongoing multi-year spectroscopic survey of novae in M33. The survey resulted in the spectroscopic classification of six novae (M33N 2006-09a, 2007-09a, 2009-01a, 2010-10a, 2010-11a, and 2011-12a) and a determination of rates of decline (t{sub 2} times) for four of them (2006-09a, 2007-09a, 2009-01a, and 2010-10a). When these data are combined with existing spectroscopic data for two additional M33 novae (2003-09a and 2008-02a), we find that five of the eight novae with available spectroscopic class appear to be members of either the He/N or Fe IIb (hybrid) classes, with only two clear members of the Fe II spectroscopic class. This initial finding is very different from what would be expected based on the results for M31 and the Galaxy where Fe II novae dominate, and the He/N and Fe IIb classes together make up only {approx}20% of the total. It is plausible that the increased fraction of He/N and Fe IIb novae observed in M33 thus far may be the result of the younger stellar population that dominates this galaxy, which is expected to produce novae that harbor generally more massive white dwarfs than those typically associated with novae in M31 or the Milky Way.

  6. Spectroscopic Orbits for 15 Late-type Stars

    NASA Astrophysics Data System (ADS)

    Willmarth, Daryl W.; Fekel, Francis C.; Abt, Helmut A.; Pourbaix, Dimitri

    2016-08-01

    Spectroscopic orbital elements are determined for 15 stars with periods from 8 to 6528 days with six orbits computed for the first time. Improved astrometric orbits are computed for two stars and one new orbit is derived. Visual orbits were previously determined for four stars, four stars are members of multiple systems, and five stars have Hipparcos “G” designations or have been resolved by speckle interferometry. For the nine binaries with previous spectroscopic orbits, we determine improved or comparable elements. For HD 28271 and HD 200790, our spectroscopic results support the conclusions of previous authors that the large values of their mass functions and lack of detectable secondary spectrum argue for the secondary in each case being a pair of low-mass dwarfs. The orbits given here may be useful in combination with future interferometric and Gaia satellite observations.

  7. Facebook as a tool for communication, collaboration, and informal knowledge exchange among members of a multisite family health team

    PubMed Central

    Lofters, Aisha K; Slater, Morgan B; Nicholas Angl, Emily; Leung, Fok-Han

    2016-01-01

    Objective To implement and evaluate a private Facebook group for members of a large Ontario multisite Family Health Team (FHT) to facilitate improved communication and collaboration. Design Program implementation and subsequent survey of team members. Setting A large multisite FHT in Toronto, Ontario. Participants Health professionals of the FHT. Main outcome measures Usage patterns and self-reported perceptions of the Facebook group by team members. Results At the time of the evaluation survey, the Facebook group had 43 members (37.4% of all FHT members). Activity in the group was never high, and posts by team members who were not among the researchers were infrequent throughout the study period. The content of posts fell into two broad categories: 1) information that might be useful to various team members and 2) questions posed by team members that others might be able to answer. Of the 26 team members (22.6%) who completed the evaluation survey, many reported that they never logged into the Facebook page (16 respondents), and never used it to communicate with team members outside of their own site of practice (19 respondents). Only six respondents reported no concerns with using Facebook as a professional communication tool; the most frequent concerns were regarding personal and patient privacy. Conclusion The use of social media by health care practitioners is becoming ubiquitous. However, the issues of privacy concerns and determining how to use social media without adding to provider workload must be addressed to make it a useful tool in health care. PMID:26869796

  8. Ten Steps to Conducting a Large, Multi-Site, Longitudinal Investigation of Language and Reading in Young Children

    PubMed Central

    Farquharson, Kelly; Murphy, Kimberly A.

    2016-01-01

    Purpose: This paper describes methodological procedures involving execution of a large-scale, multi-site longitudinal study of language and reading comprehension in young children. Researchers in the Language and Reading Research Consortium (LARRC) developed and implemented these procedures to ensure data integrity across multiple sites, schools, and grades. Specifically, major features of our approach, as well as lessons learned, are summarized in 10 steps essential for successful completion of a large-scale longitudinal investigation in early grades. Method: Over 5 years, children in preschool through third grade were administered a battery of 35 higher- and lower-level language, listening, and reading comprehension measures (RCM). Data were collected from children, their teachers, and their parents/guardians at four sites across the United States. Substantial and rigorous effort was aimed toward maintaining consistency in processes and data management across sites for children, assessors, and staff. Conclusion: With appropriate planning, flexibility, and communication strategies in place, LARRC developed and executed a successful multi-site longitudinal research study that will meet its goal of investigating the contribution and role of language skills in the development of children's listening and reading comprehension. Through dissemination of our design strategies and lessons learned, research teams embarking on similar endeavors can be better equipped to anticipate the challenges. PMID:27064308

  9. Fourier transform infrared spectroscopic study of truffles

    NASA Astrophysics Data System (ADS)

    Zhao, Dezhang; Liu, Gang; Song, Dingshan; Liu, Jian-hong; Zhou, Yilan; Ou, Jiaming; Sun, Shizhong

    2006-01-01

    Truffles are rare wild growing edible mushrooms belonging to Ascomycetes. In this paper, Fourier transform infrared (FTIR) spectroscopy was used to obtain vibrational spectra of truffles. The results show that the mushrooms exhibit characteristic spectra. The two strongest absorption bands appear at about 1077cm -1 and 1040 cm -1, which were described as C-O stretching in carbohydrate. The vibrational spectra indicate that the main compositions of the truffles are polysaccharide and protein. According to the characteristics bands and absorption ratios of spectra, different species of truffles can be discriminated. It is also found the great changes between moldy and healthy truffles, which the major differences are observed in the bands of protein. In addition, FTIR spectral differences are observed between the same species of truffles from different producing areas. It is showed that the FTIR spectroscopic method is valuable tool for rapid and nondestructive analysis of truffles prior to any extraction method used.

  10. From the (1B) Spectroscopic State to the Photochemical Product of the Ultrafast Ring-Opening of 1,3-Cyclohexadiene: A Spectral Observation of the Complete Reaction Path.

    PubMed

    Pemberton, Christine C; Zhang, Yao; Saita, Kenichiro; Kirrander, Adam; Weber, Peter M

    2015-08-20

    All stages of the electrocyclic ring-opening of 1,3-cyclohexadiene (CHD) were observed by time-resolved photoionization-photoelectron spectroscopy. Spectra of the 1B state, previously unobserved using time-resolved methods, were obtained upon optical excitation using ultrashort laser pulses at 4.60 or 4.65 eV, followed by ionization with pulses at 3.81, 3.85, and 4.10 eV, revealing a 1B lifetime of 30 fs. In an experiment using 3.07 eV probe photons and a 4.69 eV pump, we observed a time-sequenced progression of Rydberg states that includes s, p, and d states of the series n = 3 to 6. The sequentiality of the Rydberg signals points to an ionization mechanism that captures the molecule on different points along the reaction path in 2A. A dynamic fit of the Rydberg signals, coupled with MS-CASPT2 calculations, reveals that as the wavepacket moves down the potential energy surface it acquires kinetic energy at a rate of 28 eV/ps before reaching the conical intersection to the 1A ground state. During the reaction, the terminal carbon atoms separate at a speed of 16 Å/ps. A deconvolution of the Rydberg signals from a broad feature assigned to structurally disperse 1,3,5-hexatriene (HT) shows the formation of the open-chain hexatriene structure with an onset 142 fs after the initial absorption of a pump photon. The experimental observations are discussed in the context of recent ultrafast X-ray scattering experiments and theoretical quantum dynamics simulations. PMID:26192201

  11. Acrylonitrile is a multisite carcinogen in male and female B6C3F1 mice.

    PubMed

    Ghanayem, Burhan I; Nyska, Abraham; Haseman, Joseph K; Bucher, John R

    2002-07-01

    Acrylonitrile is a heavily produced unsaturated nitrile, which is used in the production of synthetic fibers, plastics, resins, and rubber. Acrylonitrile is a multisite carcinogen in rats after exposure via gavage, drinking water, or inhalation. No carcinogenicity studies of acrylonitrile in a second animal species were available. The current studies were designed to assess the carcinogenicity of acrylonitrile in B6C3F1 mice of both sexes. Acrylonitrile was administered by gavage at 0, 2.5, 10, or 20 mg/kg/day, 5 days per week, for 2 years. Urinary thiocyanate and N-acetyl-S-(2-cyanoethyl)-L-cysteine were measured as markers of exposure to acrylonitrile. In general, there were dose-related increases in urinary thiocyanate and N-acetyl-S-(2-cyanoethyl)-L-cysteine concentrations in all dosed groups of mice and at all time points. Survival was significantly (p < 0.001) reduced in the top dose (20 mg/kg) group of male and female mice relative to controls. The incidence of forestomach papillomas and carcinomas was increased in mice of both sexes in association with an increase in forestomach epithelial hyperplasia. The incidence of Harderian gland adenomas and carcinomas was also markedly increased in the acrylonitrile-dosed groups. In female mice, the incidence of benign or malignant granulosa cell tumors (combined) in the ovary in the 10 mg/kg dose group was greater than that in the vehicle control group, but because of a lack of dose response, this was considered an equivocal finding. In addition, the incidences of atrophy and cysts in the ovary of the 10 and 20 mg/kg dose groups were significantly increased. The incidences of alveolar/bronchiolar adenoma or carcinoma (combined) were significantly increased in female mice treated with acrylonitrile at 10 mg/kg/day for 2 years. This was also considered an equivocal result. In conclusion, these studies demonstrated that acrylonitrile causes multiple carcinogenic effects after gavage administration to male and female B6

  12. Spectroscopic enhancement in nanoparticles embedded glasses

    NASA Astrophysics Data System (ADS)

    Sahar, M. R.; Ghoshal, S. K.

    2014-09-01

    This presentation provides an overview of the recent progress in the enhancement of the spectroscopic characteristics of the glass embedded with nanoparticles (NPs). Some of our research activities with few significantly new results are highlighted and facilely analyzed. The science and technology dealing with the manipulation of the physical properties of rare earth doped inorganic glasses by embedding metallic NPs or nanoclusters produce the so-called 'nanoglass'. Meanwhile, the spectroscopic enhancement relates the intensity of the luminescence measured at certain transition. The enhancement which expectedly due to the 'plasmonics wave' (referring to the coherent coupling of photons to free electron oscillations called plasmon) occurs at the interface between a conductor and a dielectric. Plasmonics being an emerging concept in advanced optical material of nanophotonics has given this material the ability to exploit the optical response at nanoscale and opened up a new avenue in metal-based glass optics. There is a vast array of plasmonic NPs concepts yet to be explored, with applications spanning solar cells, (bio) sensing, communications, lasers, solid-state lighting, waveguides, imaging, optical data transfer, display and even bio-medicine. Localized surface plasmon resonance (LSPR) can enhance the optical response of nanoglass by orders of magnitude as observed. The luminescence enhancement and surface enhanced Raman scattering (SERS) are new paradigm of research. The enhancement of luminescence due to the influence of metallic NPs is the recurring theme of this paper.

  13. Spectroscopic enhancement in nanoparticles embedded glasses

    SciTech Connect

    Sahar, M. R. Ghoshal, S. K.

    2014-09-25

    This presentation provides an overview of the recent progress in the enhancement of the spectroscopic characteristics of the glass embedded with nanoparticles (NPs). Some of our research activities with few significantly new results are highlighted and facilely analyzed. The science and technology dealing with the manipulation of the physical properties of rare earth doped inorganic glasses by embedding metallic NPs or nanoclusters produce the so-called 'nanoglass'. Meanwhile, the spectroscopic enhancement relates the intensity of the luminescence measured at certain transition. The enhancement which expectedly due to the 'plasmonics wave' (referring to the coherent coupling of photons to free electron oscillations called plasmon) occurs at the interface between a conductor and a dielectric. Plasmonics being an emerging concept in advanced optical material of nanophotonics has given this material the ability to exploit the optical response at nanoscale and opened up a new avenue in metal-based glass optics. There is a vast array of plasmonic NPs concepts yet to be explored, with applications spanning solar cells, (bio) sensing, communications, lasers, solid-state lighting, waveguides, imaging, optical data transfer, display and even bio-medicine. Localized surface plasmon resonance (LSPR) can enhance the optical response of nanoglass by orders of magnitude as observed. The luminescence enhancement and surface enhanced Raman scattering (SERS) are new paradigm of research. The enhancement of luminescence due to the influence of metallic NPs is the recurring theme of this paper.

  14. Spectroscopic characterization of nitroaromatic landmine signature explosives

    NASA Astrophysics Data System (ADS)

    Hernandez-Rivera, Samuel P.; Manrique-Bastidas, Cesar A.; Blanco, Alejandro; Primera, Oliva M.; Pacheco, Leonardo C.; Castillo-Chara, Jairo; Castro, Miguel E.; Mina, Nairmen

    2004-09-01

    TNT and DNT are important explosives used as base charges of landmines and other explosive devices. They are often combined with RDX in specific explosive formulations. Their detection in vapor phase as well as in soil in contact with the explosives is important in landmine detection technology. The spectroscopic signatures of nitroaromatic compounds in neat forms: crystals, droplets, and recrystallized samples were determined by Raman Microspectroscopy (RS), Fourier Transform Infrared Microscopy (FTIR) and Fiber Optics Coupled - Fourier Transform Infrared Spectroscopy (FOC-FTIR) using a grazing angle (GA) probe. TNT exhibits a series of characteristic bands: vibrational signatures, which allow its detection in soil. The spectroscopic signature of neat TNT is dominated by strong bands about 1380 and 2970 cm-1. The intensity and position of these bands were found remarkably different in soil samples spiked with TNT. The 1380 cm-1 band is split into a number of bands in that region. The 2970 cm-1 band is reduced in intensity and new bands are observed about 2880 cm-1. The results are consistent with a different chemical environment of TNT in soil as compared to neat TNT. Interactions were found to be dependent on the physical source of the explosive. In the case of DNT-sand interactions, shifts in vibrational frequencies of the explosives as well as the substrates were found.

  15. The Setting-up of Multi-Site School Collaboratives: The Benefits of This Organizational Reform in Terms of Networking Opportunities and Their Effects

    ERIC Educational Resources Information Center

    Mifsud, Denise

    2015-01-01

    This article, which is set within the Maltese education scenario of unfolding decentralization through the setting-up of multi-site school collaboratives (legally termed "colleges") via a policy mandate, explores a particular aspect of this reform--that of "networking". This is examined in terms of the potential for…

  16. The Development of a Strategic Plan To Provide a Multisite Electronic Engineering Technology Program at the Community College of Allegheny County.

    ERIC Educational Resources Information Center

    Cunningham, Pearly

    A project was undertaken to develop a strategic plan to implement a multisite electronic engineering technology (EET) program at Pennsylvania's Community College of Allegheny County. Specifically, the project sought to determine how electronic communication technologies could provide a virtual learning community for the program; appropriate plans…

  17. WWC Review of the Report "Transfer Incentives for High-Performing Teachers: Final Results from a Multisite Randomized Experiment." What Works Clearinghouse Single Study Review

    ERIC Educational Resources Information Center

    What Works Clearinghouse, 2015

    2015-01-01

    For the 2013 study, "Transfer Incentives for High-Performing Teachers: Final Results from a Multisite Randomized Experiment," researchers examined the impact of the Talent Transfer Initiative (TTI) on students' reading and mathematics achievement in 10 school districts. The TTI enabled principals of low-performing schools to provide…

  18. The Study to Explore Early Development (SEED): A Multisite Epidemiologic Study of Autism by the Centers for Autism and Developmental Disabilities Research and Epidemiology (CADDRE) Network

    ERIC Educational Resources Information Center

    Schendel, Diana E.; DiGuiseppi, Carolyn; Croen, Lisa A.; Fallin, M. Daniele; Reed, Philip L.; Schieve, Laura A.; Wiggins, Lisa D.; Daniels, Julie; Grether, Judith; Levy, Susan E.; Miller, Lisa; Newschaffer, Craig; Pinto-Martin, Jennifer; Robinson, Cordelia; Windham, Gayle C.; Alexander, Aimee; Aylsworth, Arthur S.; Bernal, Pilar; Bonner, Joseph D.; Blaskey, Lisa; Bradley, Chyrise; Collins, Jack; Ferretti, Casara J.; Farzadegan, Homayoon; Giarelli, Ellen; Harvey, Marques; Hepburn, Susan; Herr, Matthew; Kaparich, Kristina; Landa, Rebecca; Lee, Li-Ching; Levenseller, Brooke; Meyerer, Stacey; Rahbar, Mohammad H.; Ratchford, Andria; Reynolds, Ann; Rosenberg, Steven; Rusyniak, Julie; Shapira, Stuart K.; Smith, Karen; Souders, Margaret; Thompson, Patrick Aaron; Young, Lisa; Yeargin-Allsopp, Marshalyn

    2012-01-01

    The Study to Explore Early Development (SEED), a multisite investigation addressing knowledge gaps in autism phenotype and etiology, aims to: (1) characterize the autism behavioral phenotype and associated developmental, medical, and behavioral conditions and (2) investigate genetic and environmental risks with emphasis on immunologic, hormonal,…

  19. The Challenges and Benefits of Employing a Mobile Research Fellow to Facilitate Team Work on a Large, Interdisciplinary, Multi-Sited Project

    ERIC Educational Resources Information Center

    Sugden, Fraser; Punch, Samantha

    2014-01-01

    Over the last few years research funding has increasingly moved in favour of large, multi-partner, interdisciplinary and multi-site research projects. This article explores the benefits and challenges of employing a full-time research fellow to work across multiple field sites, with all the local research teams, on an international,…

  20. Sensitivity of the Modified Children's Yale-Brown Obsessive Compulsive Scale to Detect Change: Results from Two Multi-Site Trials

    ERIC Educational Resources Information Center

    Scahill, Lawrence; Sukhodolsky, Denis G.; Anderberg, Emily; Dimitropoulos, Anastasia; Dziura, James; Aman, Michael G.; McCracken, James; Tierney, Elaine; Hallett, Victoria; Katz, Karol; Vitiello, Benedetto; McDougle, Christopher

    2016-01-01

    Repetitive behavior is a core feature of autism spectrum disorder. We used 8-week data from two federally funded, multi-site, randomized trials with risperidone conducted by the Research Units on Pediatric Psychopharmacology Autism Network to evaluate the sensitivity of the Children's Yale-Brown Obsessive Compulsive Scale modified for autism…

  1. Sources of Site Differences in the Efficacy of a Multisite Clinical Trial: The Treatment of SSRI-Resistant Depression in Adolescents

    ERIC Educational Resources Information Center

    Spirito, Anthony; Abebe, Kaleab Z.; Iyengar, Satish; Brent, David; Vitiello, Benedetto; Clarke, Gregory; Wagner, Karen Dineen; Asarnow, Joan; Emslie, Graham; Keller, Martin

    2009-01-01

    Site differences in treatment outcomes are not often highlighted when the results of multisite randomized clinical trials (MRCTs) are reported. The primary analyses of a 6-site MRCT, the Treatment of SSRI-Resistant Depression in Adolescents (TORDIA) study, showed substantial variation by site in the performance of a medication-only condition and a…

  2. Research staff training in a multisite randomized clinical trial: Methods and recommendations from the Stimulant Reduction Intervention using Dosed Exercise (STRIDE) trial

    PubMed Central

    Walker, Robrina; Morris, David W; Greer, Tracy L; Trivedi, Madhukar H

    2014-01-01

    Background Descriptions of and recommendations for meeting the challenges of training research staff for multisite studies are limited despite the recognized importance of training on trial outcomes. The STRIDE (STimulant Reduction Intervention using Dosed Exercise) study is a multisite randomized clinical trial that was conducted at nine addiction treatment programs across the United States within the National Drug Abuse Treatment Clinical Trials Network (CTN) and evaluated the addition of exercise to addiction treatment as usual (TAU), compared to health education added to TAU, for individuals with stimulant abuse or dependence. Research staff administered a variety of measures that required a range of interviewing, technical, and clinical skills. Purpose In order to address the absence of information on how research staff are trained for multisite clinical studies, the current manuscript describes the conceptual process of training and certifying research assistants for STRIDE. Methods Training was conducted using a three-stage process to allow staff sufficient time for distributive learning, practice, and calibration leading up to implementation of this complex study. Results Training was successfully implemented with staff across nine sites. Staff demonstrated evidence of study and procedural knowledge via quizzes and skill demonstration on six measures requiring certification. Overall, while the majority of staff had little to no experience in the six measures, all research assistants demonstrated ability to correctly and reliably administer the measures throughout the study. Conclusions Practical recommendations are provided for training research staff and are particularly applicable to the challenges encountered with large, multisite trials. PMID:25379036

  3. Interracial Contact and Racial Constancy: A Multi-Site Study of Racial Intergroup Bias in 3-5 Year Old Anglo-British Children

    ERIC Educational Resources Information Center

    Rutland, Adam; Cameron, Lindsey; Bennett, Laura; Ferrell, Jennifer

    2005-01-01

    This paper examined the influence of interracial contact and racial constancy on the racial intergroup bias of young Anglo-British children. This multi-site study was conducted in areas of Great Britain that varied in terms of racial diversity. The study also investigated whether preschool children express bias on positive, but not negative,…

  4. Measurement characteristics of activity-related psychosocial measures in 8- to 10-year-old African-American girls in the Girls health Enrichment Multisite Study (GEMS)

    Technology Transfer Automated Retrieval System (TEKTRAN)

    BACKGROUND: This paper presents reliability and validity analyses of physical activity-related psychosocial questionnaires completed by 8- to 10-year-old African-American girls at baseline and follow-up assessments of pilot intervention studies in the Girls health Enrichment Multi-site Study (GEMS)....

  5. Spectroscopic characterization of polymers: report

    SciTech Connect

    Koenig, J.L.

    1987-10-01

    Polymer characterization has presented major difficulties to the analytical chemist, who has had to develop techniques to cope with the challenge. Even the elementary problem of measuring molecular weight is not easy. Yet such measurements are essential, because the physical, mechanical, and flow properties depend on the length of the polymer chain. Because of the limited solubility and high viscosity of polymers, many classical techniques have been of little use or have had to be extensively modified to measure the molecular weight of polymers. Size-exclusion chromatographic techniques such as gel permeation have been developed to measure these molecular weight distributions. Special chromatographic instruments with a range of spectroscopic detectors (including infrared and laser-light scattering) have emerged commercially to aid the analytical chemist in the fundamental endeavor to measure the length of the polymer chain and its distribution. The author describes the advantages and disadvantages and disadvantages of various spectroscopic techniques.

  6. Polyhydroxylated sapphyrins: multisite non-metallic catalysts for activated phosphodiester hydrolysis.

    PubMed

    Král, Vladimír; Lang, Kamil; Králová, Jarmila; Dvorák, Michal; Martásek, Pavel; Chin, Aileen O; Andrievsky, Andrei; Lynch, Vincent; Sessler, Jonathan L

    2006-01-18

    Enhanced hydrolysis rates for the cleavage of bis(4-nitrophenyl)phosphate (BNPP), a model phosphodiester, may be achieved by using appropriately designed ditopic receptors containing the known phosphate-binding nucleus, sapphyrin, attached covalently to suitably oriented polyhydroxyl subunits. Evidence for the interaction between sapphyrin and BNPP comes from solid-state X-ray diffraction analysis of a diprotonated dihydroxylated sapphyrin-BNPP complex and from solution-phase (31)P NMR spectroscopic binding studies. The sapphyrins described in this paper may have a role to play as oligonucleotide cleavage agents. PMID:16402829

  7. Highlights of the Brazilian Solar Spectroscope

    NASA Astrophysics Data System (ADS)

    Sawant, H. S.; Cecatto, J. R.; Mészárosová, H.; Faria, C.; Fernandes, F. C. R.; Karlický, M.; de Andrade, M. C.

    2009-07-01

    The digital, decimetric (950-2500 MHz) Brazilian Solar Spectroscope (BSS, Sawant, H.S., Subramanian, K.R., Faria, C., et al. Brazilian Solar Spectroscope (BSS). Solar Phys. 200, 167-176, 2001) with high time (10-1000 ms) and frequency (1-10 MHz) resolution is in regular operation since April, 1998, at the National Space Research Institute (INPE) at São José dos Campos, Brazil. The BSS has now been upgraded with a new digital data acquisition and data processing system. The new version of the BSS has improved the observational possibilities with the capability to record up to 200 frequency channels available in the selectable frequency range 950-2500 MHz. The GPS receiver permits the acquisition of data with time accuracy in the order of 0.1 ms. The software system of the BSS is composed by two distinct modules: the first, data acquisition system provides a flexible Graphical User Interface (GUI) that allows one to choose the observational parameters. The second module is the real time visualization system that permits real time visualization of the observed dynamic spectrum and additionally allows procedures for visualization and preliminary analysis of the recorded solar spectra. Using the new visualization system, we have realized two new types of dm-radio fine structures: narrow band type III bursts with positive as well as negative group frequency drift and dots emissions arranged in zebra-like and fiber-like chains. Furthermore, we have found flare generated fast wave trains according to their tadpole signature in wavelet power spectra for a decimetric type IV radio event (June 6, 2000 flare).

  8. A Visual-Spectroscopic Orbit for the Binary Sigma 248

    NASA Astrophysics Data System (ADS)

    Torres, Guillermo

    1995-06-01

    Spectroscopic studies of visual binaries with angular separations less than about 1" have so far had great difficulty in providing the individual radial velocities for the components, because of the small velocity differences that are typical in these systems. The recent introduction of TODCOR, a two-dimensional cross-correlation technique (Zucker and Mazeh 1994), promises to change the situation, bridging the gap between the wider pairs resolvable at the telescope, and the classical double-lined spectroscopic binaries, with large velocity amplitudes. We present the first example of an application of TODCOR to such a case: the study of the close visual pair Sigma 248. We report our high-resolution low signal-to-noise spectroscopic observations of the system over the past seven years, which happen to cover the periastron passage. Using TODCOR, we are able to disentangle the light from the two stars in our composite spectra and obtain radial velocities for both components despite the small velocity difference. By combining our velocities with all available astrometric observations of the pair we derive for the first time a visual-spectroscopic orbital solution, with a period of about 310 years. We obtain also the orbital parallax of the system, corresponding to a distance of 60 parsecs, as well as the individual masses, which are consistent with early K-type dwarfs. (SECTION: Stars)

  9. Why do patients with stroke not receive the recommended amount of active therapy (ReAcT)? Study protocol for a multisite case study investigation

    PubMed Central

    Clarke, David J; Tyson, Sarah; Rodgers, Helen; Drummond, Avril; Palmer, Rebecca; Prescott, Matthew; Tyrrell, Pippa; Burton, Louisa; Grenfell, Katie; Brkic, Lianne; Forster, Anne

    2015-01-01

    Introduction Increased frequency and intensity of inpatient therapy contributes to improved outcomes for stroke survivors. Differences exist in the amount of therapy provided internationally. In England, Wales and Northern Ireland it is recommended that a minimum of 45 min of each active therapy should be provided at least 5 days a week provided the therapy is appropriate and that the patient can tolerate this. Sentinel Stroke National Audit Programme (2014) data demonstrate this standard is not being achieved for most patients. No research been undertaken to explore how therapists in England manage their practice to meet time-specific therapy recommendations. The ReAcT study aims to develop an in-depth understanding of stroke therapy provision, including how the guideline of 45 min a day of each relevant therapy, is interpreted and implemented by therapists, and how it is experienced by stroke-survivors and their families. Methods and analysis A multisite ethnographic case study design in a minimum of six stroke units will include modified process mapping, observations of service organisation, therapy delivery and documentary analysis. Semistructured interviews with therapists and service managers (n=90), and with patients and informal carers (n=60 pairs) will be conducted. Data will be analysed using the Framework approach. Ethics and dissemination The study received a favourable ethical opinion via the National Research Ethics Service (reference number: 14/NW/0266). Participants will provide written informed consent or, where stroke-survivors lack capacity, a consultee declaration will be sought. ReAcT is designed to generate insights into the organisational, professional, social, practical and patient-related factors acting as facilitators or barriers to providing the recommended amount of therapy. Provisional recommendations will be debated in consensus meetings with stakeholders who have not participated in ReAcT case studies or interviews. Final

  10. VIOLENCE AND NON-VIOLENCE-RELATED INJURIES AND ALCOHOL IN WOMEN FROM DEVELOPED AND DEVELOPING COUNTRIES: A MULTI-SITE EMERGENCY ROOM STUDY

    PubMed Central

    da Silva, Rosiane Lopes; Diehl, Alessandra; Cherpitel, Cheryl J.; Figlie, Neliana B.

    2014-01-01

    This study sought to analyze the association between alcohol consumption and the occurrence of injuries in women attending the emergency room (ER) from developing and developed countries. The sample consisted of ER data from women in 15 countries that were collected as part of two multi-site studies using similar methodologies: the Emergency Room Collaborative Alcohol Analysis Project (ERCAAP), and World Health Organization Collaborative Study on Alcohol and Injuries (WHO Study). Women ranged in age from 18 and 98 years. Those from developed countries had higher levels of education (43% completed high-school) than women from developing countries (37%). Over half of the women from developing countries reported they had not consumed alcohol in the last 12 months (abstentious), while 2% reported drinking every day. In addition, current drinking women from developing countries reported more binge drinking episodes (33% reported 5 to 11 drinks and 15% reported 12 or more drinks on an occasion) compared to those from developed countries (28% and 11%, respectively). Violence-related injury was more prevalent in developing countries (18%) compared to developed countries (9%). An association between injury and the frequency of alcohol consumption in the last 12 months was observed in both developing and developed countries. Although women from developing countries who suffered violence-related injuries were more likely to demonstrate alcohol abstinence or have lower rates of daily alcohol consumption, these women drank in a more dangerous way, and violence-related injuries were more likely to occur in these women than in those living in developed countries. PMID:25452073

  11. Spectroscopic study of solar twins and analogues

    NASA Astrophysics Data System (ADS)

    Datson, Juliet; Flynn, Chris; Portinari, Laura

    2015-02-01

    Context. Many large stellar surveys have been and are still being carried out, providing huge amounts of data, for which stellar physical parameters will be derived. Solar twins and analogues provide a means to test the calibration of these stellar catalogues because the Sun is the best-studied star and provides precise fundamental parameters. Solar twins should be centred on the solar values. Aims: This spectroscopic study of solar analogues selected from the Geneva-Copenhagen Survey (GCS) at a resolution of 48 000 provides effective temperatures and metallicities for these stars. We test whether our spectroscopic parameters, as well as the previous photometric calibrations, are properly centred on the Sun. In addition, we search for more solar twins in our sample. Methods: The methods used in this work are based on literature methods for solar twin searches and on methods we developed in previous work to distinguish the metallicity-temperature degeneracies in the differential comparison of spectra of solar analogues versus a reference solar reflection spectrum. Results: We derive spectroscopic parameters for 148 solar analogues (about 70 are new entries to the literature) and verify with a-posteriori differential tests that our values are well-centred on the solar values. We use our dataset to assess the two alternative calibrations of the GCS parameters; our methods favour the latest revision. We show that the choice of spectral line list or the choice of asteroid or time of observation does not affect the results. We also identify seven solar twins in our sample, three of which are published here for the first time. Conclusions: Our methods provide an independent means to differentially test the calibration of stellar catalogues around the values of a well-known benchmark star, which makes our work interesting for calibration tests of upcoming Galactic surveys. Based on observations made with ESO Telescopes at the La Silla Observatory under programme ID 077.D

  12. Asiago spectroscopic classification of ASASSN-16bp

    NASA Astrophysics Data System (ADS)

    Tomasella, L.; Pastorello, A.; Benetti, S.; Cappellaro, E.; Elias-Rosa, N.; Ochner, P.; Tartaglia, L.; Terreran, G.; Turatto, M.

    2016-02-01

    The Asiago Transient Classification Program (Tomasella et al. 2014, AN, 335, 841) reports the spectroscopic classification of ASASSN-16bp ( = AT 2016adq), discovered by All Sky Automated Survey for SuperNovae ASAS-SN (see Shappee et al. 2014, ApJ, 788, 48 and http://www.astronomy.ohio-state.edu/~assassin/index.shtml ), in CGCG 336-041 (Atel #8666) The observation was performed with the Asiago 1.82 m Copernico Telescope (+AFOSC; range 340-820 nm; resolution 1.4 nm). Name | Discovery UT | Obs. Date UT |z | Type | Phase |Notes ASASSN-16bp | 20160209.61 | 20160211.11 |0.034194 | Ia | ~10d | (1) (1) Also known as SN2016adq in CGCG 336-041 (z=0.034194, d=145 Mpc, via NED).

  13. Spectroscopic Active Galaxies and Clusters Explorer

    NASA Astrophysics Data System (ADS)

    Ferrari, L.; Bagliani, D.; Bardi, A.; Battistelli, E.; Birkinshaw, M.; Colafrancesco, S.; Conte, A.; Debernardis, P.; Degregori, S.; Depetris, M.; de Zotti, G.; Donati, A.; Franceschini, A.; Gatti, F.; Gervasi, M.; Gonzalez-Nuevo, J.; Lamagna, L.; Luzzi, G.; Maiolino, M.; Marchegiani, P.; Mariani, A.; Masi, S.; Massardi, M.; Mauskopf, P.; Nati, L.; Nati, F.; Natoli, P.; Piacentini, F.; Polenta, G.; Porciani, M.; Savini, G.; Schillaci, A.; Spinelli, S.; Tartari, A.; Tavanti, M.; Tortora, A.; Vaccari, M.; Vaccarone, R.; Zannoni, M.

    2009-12-01

    We present a concept for the payload SAGACE, the Spectroscopic Active Galaxies And Cluster Explorer, devoted to study the evolution of Universe structures using different observables, all of them in the mm/submm wavelength. The SAGACE payload is made of a passively cooled 3 m telescope, a cryogenic Fourier Transform Spectrometer (FTS) and detector arrays to be operated at 0.3 K by a 3He fridge. The detectors are Ti/Au Transition Edge Sensor (TES) bolometers with a NEP<10-17 W/Hz12. A phase-A study has been recently completed for this experiment, in the framework of the call for small missions of the Italian Space Agency.

  14. Search for planets by spectroscopic methods

    NASA Technical Reports Server (NTRS)

    Serkowski, K.

    1980-01-01

    Spectroscopic means of detecting the motion of a star around a star-planet barycenter are considered. The precision of such an observation, which requires a radial velocity error of not more than 5 m/sec, is discussed in relation to the spectral resolutions of the detectors utilized. The University of Arizona radial velocity spectrometer is then presented, with particular attention given to the location of the absorption cell in a beam of light from an incandescent bulb, high-accuracy wavelength calibration involving the use of a Fabry-Perot interferometer in front of an echelle spectrograph, and future plans for the use of light reflected from a Fabry-Perot etalon to improve transmittance. On the basis of these techniques, it is expected that radial velocities with accuracies sufficient for the detection of extrasolar planets will be obtained.

  15. Spectroscopic behavior of bioconjugated quantum dots

    NASA Astrophysics Data System (ADS)

    Chornokur, G.; Ostapenko, S.; Emirov, Yu; Korsunska, N. E.; Sellers, T.; Phelan, C.

    2008-07-01

    We report on a short-wavelength, 'blue' spectral shift of the photoluminescence (PL) spectrum in CdSeTe/ZnS core/shell quantum dots (QDs) caused by bioconjugation with several monoclonal cancer-related antibodies (ABs). Scanning PL spectroscopy was performed on samples dried on solid substrates at various temperatures. The influence of the AB chemical origin on the PL spectral shift was observed. The QD-AB conjugation reaction was confirmed using the agarose gel electrophoresis technique. The spectral shift was strongly increased and the process facilitated when the samples were dried above room temperature. The PL spectroscopic mapping revealed a profile of the PL spectral shift across the dried QD-AB spot. A mechanism of the blue shift is attributed to changes in the QD electronic energy levels caused by a local stress applied to the bioconjugated QD.

  16. Spectroscopic data for thermal infrared remote sensing

    NASA Technical Reports Server (NTRS)

    Varanasi, P.; Nemtchinov, V.; Li, Z.

    1995-01-01

    There has been extensive world-wide use of chloro-fluoro-carbons (CFC's), especially CFC-11 (CFCl3) and CFC-12 (CF2Cl2), hydro-chloro-fluoro-carbons (HCFC's), HCFC-22 (CHFCl2) in particular, and sulphur hexaflouride (SF6) in numerous many industrial applications. These chemicals possess either a strong ozone-depletion potential or a global-warming potential, or both, and pose a threat to the inhabitability of our planet. Recognition of this fact has led to significant curtailment, if not total banishment, of their use globally. However, as recent satellite observations have shown, decline in their atmospheric concentrations may not be immediate. The marked depletion of ozone which has been observed in recent years at high latitudes has made infrared remote sensing of the atmosphere an activity of high priority. The success of any infrared remote sensing experiment conducted in the atmosphere depends upon the availability of accurate, high-resolution, spectroscopic data that are applicable to that experiment. This paper presents a preliminary phase of a multi-faceted work using a Fourier-transform spectrometer (FTS) which is in progress in our laboratory. The concept of how laboratory-borne measurements can be geared toward obtaining a database that is directly applicable to satellite-borne remote sensing missions is the main thrust of this paper which addresses itself to ongoing or planned international space missions. Spectroscopic data on the unresolvable bands of the above mentioned as well as several other man-made gases and on the individual spectral lines of such naturally present trace gases as CO2, N2O, NH3, and CH4 are presented. There is often significant overlap between the isolated lines of better known bands of the more abundant species and the weaker absorption features identifiable as bands of the currently less abundant CFC's, HCFC's, and SF6.

  17. Revealing the ISM in high redshift starburst galaxies: An analysis of Herschel PACS and SPIRE FTS spectroscopic observations of HerMES and H-ATLAS-selected lensed galaxies

    NASA Astrophysics Data System (ADS)

    Cooray, Asantha

    In the quest to develop a fundamental understanding of galaxy formation and evolution, observations of dusty star-forming galaxies (DSFGs) promise significant progress this decade. The importance of DSFGs is highlighted by the fact that half of the energy emitted by extragalactic sources emerges as dust-reprocessed light at infrared (IR) to sub millimeter wavelength. In the post-herschel\\ era, we are now at a unique position to tackle some of the key questions on galaxy formation and evolution because of the large area Herschel's Key Project surveys (HerMES and H-ATLAS). In particular those surveys have allowed us to identify a sample of 250 strongly gravitationally lensed DSFGs at z > 1. They give us a unique opportunity to dissect the detailed structures and kinematics of DSFGs. The Herschel Science Archive also contains individual follow up data on 44 and 25 of the brightest sources with SPIRE-FTS and PACS, respectively, in the spectroscopy mode, taking over 250 hours in four open-time programs. Only one of the 44 SPIRE FTS targets has yet to appear in the published literature. One of the four include an open-time 2 PACS spectroscopy program that was led at UCI by a former postdoc from the PI's group. That program was initially approved at Priority 2 in 2011, but was triggered in late 2012 and achieved 100% completion during the last two weeks of Herschel lifetime in May 2013. This archival analysis, interpretation, and modeling program involves two parts: (i) PACS spectroscopy in 50 to 200 microns of 25 lensed galaxies in the fine-structure emission lines [SiII]34, [SIII]33, [OIV]26, [OIII]52, [NIII]57 and [OI]63, and the molecular hydrogen H_2 S(0) and S(1). (ii) SPIRE FTS spectroscopy of 44 lensed galaxies, including above 25, over the wavelength range of 200 to 600 microns targeting [CII]158, [OIII]88, [OI]63/145, and [NI]122. The analysis will lead to a better understanding of the ISM of starbursting galaxies that span 1 < z < 3.1 range in redshift and a

  18. Cesium migration in Hanford sediment: a multisite cation exchange model based on laboratory transport experiments

    NASA Astrophysics Data System (ADS)

    Steefel, Carl I.; Carroll, Susan; Zhao, Pihong; Roberts, Sarah

    2003-12-01

    Cs + transport experiments carried out in columns packed with uncontaminated Hanford formation sediment from the SX tank farm provide strong support for the use of a multisite, multicomponent cation exchange model to describe Cs + migration in the Hanford vadose zone. The experimental results indicate a strong dependence of the effective Cs +Kd on the concentrations of other cations, including Na + that is present at high to extremely high concentrations in fluids leaking from the Hanford SX tanks. A strong dependence of the Cs +Kd on the aqueous Cs + concentration is also apparent, with retardation of Cs + increasing from a value of 41 at a Cs + concentration of 10 -4 M in the feed solution to as much as 282 at a Cs + concentration of 5×10 -7 M, all in a background of 1 M NaNO 3. The total cation exchange capacity (CEC) of the Hanford sediment was determined using 22Na isotopic equilibrium exchange in a flow-through column experiment. The value for the CEC of 120 μeq/g determined with this method is compatible with a value of 121.9 μeq/g determined by multi-cation elution. While two distinct exchange sites were proposed by Zachara et al. [Geochim. Cosmochim. Acta 66 (2002) 193] based on binary batch exchange experiments, a third site is proposed in this study to improve the fit of the Cs +-Na + and Cs +-Ca + exchange data and to capture self-sharpened Cs + breakthrough curves at low concentrations of Cs +. Two of the proposed exchange sites represent frayed edge sites (FES) on weathered micas and constitute 0.02% and 0.22% of the total CEC. Both of the FES show a very strong selectivity for Cs + over Na + ( KNa-Cs=10 7.22 and 10 4.93, respectively). The third site, accounting for over 99% of the total CEC, is associated with planar sites on expansible clays and shows a smaller Na +-Cs + selectivity coefficient of 10 1.99. Parameters derived from a fit of binary batch experiments alone tend to under predict Cs + retardation in the column experiments. The

  19. Cesium migration in Hanford sediment: a multisite cation exchange model based on laboratory transport experiments.

    PubMed

    Steefel, Carl I; Carroll, Susan; Zhao, Pihong; Roberts, Sarah

    2003-12-01

    Cs+ transport experiments carried out in columns packed with uncontaminated Hanford formation sediment from the SX tank farm provide strong support for the use of a multisite, multicomponent cation exchange model to describe Cs+ migration in the Hanford vadose zone. The experimental results indicate a strong dependence of the effective Cs+ Kd on the concentrations of other cations, including Na+ that is present at high to extremely high concentrations in fluids leaking from the Hanford SX tanks. A strong dependence of the Cs+ Kd on the aqueous Cs+ concentration is also apparent, with retardation of Cs+ increasing from a value of 41 at a Cs+ concentration of 10(-4) M in the feed solution to as much as 282 at a Cs+ concentration of 5x10(-7) M, all in a background of 1 M NaNO3. The total cation exchange capacity (CEC) of the Hanford sediment was determined using 22Na isotopic equilibrium exchange in a flow-through column experiment. The value for the CEC of 120 microeq/g determined with this method is compatible with a value of 121.9 microeq/g determined by multi-cation elution. While two distinct exchange sites were proposed by Zachara et al. [Geochim. Cosmochim. Acta 66 (2002) 193] based on binary batch exchange experiments, a third site is proposed in this study to improve the fit of the Cs+-Na+ and Cs+-Ca+ exchange data and to capture self-sharpened Cs+ breakthrough curves at low concentrations of Cs+. Two of the proposed exchange sites represent frayed edge sites (FES) on weathered micas and constitute 0.02% and 0.22% of the total CEC. Both of the FES show a very strong selectivity for Cs+ over Na+ (K(Na-Cs)=10(7.22) and 10(4.93), respectively). The third site, accounting for over 99% of the total CEC, is associated with planar sites on expansible clays and shows a smaller Na+-Cs+ selectivity coefficient of 10(1.99). Parameters derived from a fit of binary batch experiments alone tend to under predict Cs+ retardation in the column experiments. The transport

  20. Completion Report for Multi-Site Incentive MRT 2779 Implement ASC Tripod Initiative by 30SEP08

    SciTech Connect

    East, D; Cerutti, J; Noe, J; Cupps, K; Loncaric, J; Sturtevant, J

    2008-09-22

    This report provides documentation and evidence for the completion of the deployment of the Tripod common operating system (TripodOS, also known as and generally referred to below as TOSS). Background documents for TOSS are provided in Appendices A and B, including the initial TOSS proposal accepted by ASC HQ and Executives in July 2007 and a Governance Model defined by a Tri-Lab working group in September 2007. Appendix C contains a document that clarifies the intent and requirements for the completion criteria associated with MRT 2779. The deployment of TOSS is a Multi-Site Incentive from the ASC FY08-09 Implementation Plan due at the end of Quarter 4 in FY08.

  1. A MultiSite Gateway Toolkit for Rapid Cloning of Vertebrate Expression Constructs with Diverse Research Applications

    PubMed Central

    Fowler, Daniel K.; Stewart, Scott; Seredick, Steve; Eisen, Judith S.

    2016-01-01

    Recombination-based cloning is a quick and efficient way to generate expression vectors. Recent advancements have provided powerful recombinant DNA methods for molecular manipulations. Here, we describe a novel collection of three-fragment MultiSite Gateway cloning system-compatible vectors providing expanded molecular tools for vertebrate research. The components of this toolkit encompass a broad range of uses such as fluorescent imaging, dual gene expression, RNA interference, tandem affinity purification, chemically-inducible dimerization and lentiviral production. We demonstrate examples highlighting the utility of this toolkit for producing multi-component vertebrate expression vectors with diverse primary research applications. The vectors presented here are compatible with other Gateway toolkits and collections, facilitating the rapid generation of a broad range of innovative DNA constructs for biological research. PMID:27500400

  2. Development of a Multi-Site and Multi-Device Webgis-Based Tool for Tidal Current Energy Development

    NASA Astrophysics Data System (ADS)

    Ang, M. R. C. O.; Panganiban, I. K.; Mamador, C. C.; De Luna, O. D. G.; Bausas, M. D.; Cruz, J. P.

    2016-06-01

    A multi-site, multi-device and multi-criteria decision support tool designed to support the development of tidal current energy in the Philippines was developed. Its platform is based on Geographic Information Systems (GIS) which allows for the collection, storage, processing, analyses and display of geospatial data. Combining GIS tools with open source web development applications, it becomes a webGIS-based marine spatial planning tool. To date, the webGIS-based tool displays output maps and graphs of power and energy density, site suitability and site-device analysis. It enables stakeholders and the public easy access to the results of tidal current energy resource assessments and site suitability analyses. Results of the initial development showed that it is a promising decision support tool for ocean renewable energy project developments.

  3. Predictors of Condom Use in a Multi-Site Study of High-Risk Youth Living with HIV

    PubMed Central

    Outlaw, Angulique; Naar-King, Sylvie; Parsons, Jeffrey T.; Janisse, Heather

    2010-01-01

    Risky sexual behavior among youth living with HIV (YLH) must be addressed to prevent the spread of the disease. The purpose of the current study was to investigate factors associated with condom use in a multi-site sample of YLH (ages 16-24). Baseline assessments were conducted with 186 YLH using a computer assisted personal interviewing (CAPI) method. Path analysis suggested that condom use was directly predicted by motivational readiness and self-efficacy for safer sex. Interventions that promote self-efficacy and motivational readiness through a variety of mechanisms may be useful in understanding and conceptualizing sexual risk behavior in YLH. However, further predictors must be studied to account for more variance. PMID:20166783

  4. A SPECTROSCOPIC ANALYSIS OF WHITE DWARFS IN THE KISO SURVEY

    SciTech Connect

    Limoges, M.-M.; Bergeron, P. E-mail: bergeron@astro.umontreal.c

    2010-05-10

    We present a spectroscopic analysis of white dwarfs found in the Kiso survey. Spectroscopic observations at high signal-to-noise ratio have been obtained for all DA and DB stars in the Kiso Schmidt ultraviolet excess survey (KUV stars). These observations led to the reclassification of several KUV objects, including the discovery of three unresolved DA+DB double-degenerate binaries. The atmospheric parameters (T{sub eff} and log g) are obtained from detailed model atmosphere fits to optical spectroscopic data. The mass distribution of our sample is characterized by a mean value of 0.606 M{sub sun} and a dispersion of 0.135 M{sub sun} for DA stars, and 0.758 M{sub sun} and a dispersion of 0.192 M{sub sun} for DB stars. Absolute visual magnitudes obtained from our spectroscopic fits allow us to derive an improved luminosity function for the DA and DB stars identified in the Kiso survey. Our luminosity function is found to be significantly different from earlier estimates based on empirical photometric calibrations of M{sub V} for the same sample. The results for the DA stars now appear entirely consistent with those obtained for the PG survey using the same spectroscopic approach. The space density for DA stars with M{sub V} {<=} 12.75 is 2.80 x 10{sup -4} pc{sup -3} in the Kiso survey, which is 9.6% smaller than the value found in the PG survey. The completeness of both surveys is briefly discussed.

  5. The GEISA Spectroscopic Database System in its latest Edition

    NASA Astrophysics Data System (ADS)

    Jacquinet-Husson, N.; Crépeau, L.; Capelle, V.; Scott, N. A.; Armante, R.; Chédin, A.

    2009-04-01

    GEISA (Gestion et Etude des Informations Spectroscopiques Atmosphériques: Management and Study of Spectroscopic Information)[1] is a computer-accessible spectroscopic database system, designed to facilitate accurate forward planetary radiative transfer calculations using a line-by-line and layer-by-layer approach. It was initiated in 1976. Currently, GEISA is involved in activities related to the assessment of the capabilities of IASI (Infrared Atmospheric Sounding Interferometer on board the METOP European satellite -http://earth-sciences.cnes.fr/IASI/)) through the GEISA/IASI database[2] derived from GEISA. Since the Metop (http://www.eumetsat.int) launch (October 19th 2006), GEISA/IASI is the reference spectroscopic database for the validation of the level-1 IASI data, using the 4A radiative transfer model[3] (4A/LMD http://ara.lmd.polytechnique.fr; 4A/OP co-developed by LMD and Noveltis with the support of CNES). Also, GEISA is involved in planetary research, i.e.: modelling of Titan's atmosphere, in the comparison with observations performed by Voyager: http://voyager.jpl.nasa.gov/, or by ground-based telescopes, and by the instruments on board the Cassini-Huygens mission: http://www.esa.int/SPECIALS/Cassini-Huygens/index.html. The updated 2008 edition of GEISA (GEISA-08), a system comprising three independent sub-databases devoted, respectively, to line transition parameters, infrared and ultraviolet/visible absorption cross-sections, microphysical and optical properties of atmospheric aerosols, will be described. Spectroscopic parameters quality requirement will be discussed in the context of comparisons between observed or simulated Earth's and other planetary atmosphere spectra. GEISA is implemented on the CNES/CNRS Ether Products and Services Centre WEB site (http://ether.ipsl.jussieu.fr), where all archived spectroscopic data can be handled through general and user friendly associated management software facilities. More than 350 researchers are

  6. Spectroscopic signature for ferroelectric ice

    NASA Astrophysics Data System (ADS)

    Wójcik, Marek J.; Gług, Maciej; Boczar, Marek; Boda, Łukasz

    2014-09-01

    Various forms of ice exist within our galaxy. Particularly intriguing type of ice - ‘ferroelectric ice' was discovered experimentally and is stable in temperatures below 72 K. This form of ice can generate enormous electric fields and can play an important role in planetary formation. In this letter we present Car-Parrinello simulation of infrared spectra of ferroelectric ice and compare them with spectra of hexagonal ice. Librational region of the spectra can be treated as spectroscopic signature of ice XI and can be of help to identify ferroelectric ice in the Universe.

  7. The far ultraviolet spectroscopic explorer

    NASA Technical Reports Server (NTRS)

    Boggess, A.

    1982-01-01

    The scientific objectives and performance characteristics of a new astronomy mission referred to as the far ultraviolet spectroscopic explorer, or FUSE are being defined by a team involving people experienced instrumental requirements that best meet the scientific needs. The team is intended to have a lifetime of about one year, ending with the submission of a report to NASA which could be used as the basis for an engineering design study. The principal objective of FUSE is to obtain astronomical spectra at wavelengths shorter than is possible with the Space Telescope.

  8. Thirty New Low-mass Spectroscopic Binaries

    NASA Astrophysics Data System (ADS)

    Shkolnik, Evgenya L.; Hebb, Leslie; Liu, Michael C.; Reid, I. Neill; Collier Cameron, Andrew

    2010-06-01

    As part of our search for young M dwarfs within 25 pc, we acquired high-resolution spectra of 185 low-mass stars compiled by the NStars project that have strong X-ray emission. By cross-correlating these spectra with radial velocity standard stars, we are sensitive to finding multi-lined spectroscopic binaries. We find a low-mass spectroscopic binary fraction of 16% consisting of 27 SB2s, 2 SB3s, and 1 SB4, increasing the number of known low-mass spectroscopic binaries (SBs) by 50% and proving that strong X-ray emission is an extremely efficient way to find M-dwarf SBs. WASP photometry of 23 of these systems revealed two low-mass eclipsing binaries (EBs), bringing the count of known M-dwarf EBs to 15. BD-22 5866, the ESB4, was fully described in 2008 by Shkolnik et al. and CCDM J04404+3127 B consists of two mid-M stars orbiting each other every 2.048 days. WASP also provided rotation periods for 12 systems, and in the cases where the synchronization time scales are short, we used P rot to determine the true orbital parameters. For those with no P rot, we used differential radial velocities to set upper limits on orbital periods and semimajor axes. More than half of our sample has near-equal-mass components (q > 0.8). This is expected since our sample is biased toward tight orbits where saturated X-ray emission is due to tidal spin-up rather than stellar youth. Increasing the samples of M-dwarf SBs and EBs is extremely valuable in setting constraints on current theories of stellar multiplicity and evolution scenarios for low-mass multiple systems. Based on observations collected at the W. M. Keck Observatory, the Canada-France-Hawaii Telescope and by the WASP Consortium. The Keck Observatory is operated as a scientific partnership between the California Institute of Technology, the University of California, and NASA, and was made possible by the generous financial support of the W. M. Keck Foundation. The CFHT is operated by the National Research Council of Canada

  9. Neutron-Proton Asymmetry Dependence of Spectroscopic Factors in Ar Isotopes

    NASA Astrophysics Data System (ADS)

    Lee, Jenny; Tsang, M. B.; Bazin, D.; Coupland, D.; Henzl, V.; Henzlova, D.; Kilburn, M.; Lynch, W. G.; Rogers, A. M.; Sanetullaev, A.; Signoracci, A.; Sun, Z. Y.; Youngs, M.; Chae, K. Y.; Charity, R. J.; Cheung, H. K.; Famiano, M.; Hudan, S.; O'Malley, P.; Peters, W. A.; Schmitt, K.; Shapira, D.; Sobotka, L. G.

    2010-03-01

    Spectroscopic factors have been extracted for proton-rich Ar34 and neutron-rich Ar46 using the (p, d) neutron transfer reaction. The experimental results show little reduction of the ground state neutron spectroscopic factor of the proton-rich nucleus Ar34 compared to that of Ar46. The results suggest that correlations, which generally reduce such spectroscopic factors, do not depend strongly on the neutron-proton asymmetry of the nucleus in this isotopic region as was reported in knockout reactions. The present results are consistent with results from systematic studies of transfer reactions but inconsistent with the trends observed in knockout reaction measurements.

  10. Neutron-Proton Asymmetry Dependence of Spectroscopic Factors in Ar Isotopes

    SciTech Connect

    Lee, Jenny; Tsang, Betty; Shapira, Dan

    2010-01-01

    Spectroscopic factors have been extracted for proton-rich 34Ar and neutron-rich 46Ar using the (p, d) neutron transfer reaction. The experimental results show little reduction of the ground state neutron spectroscopic factor of the proton-rich nucleus 34Ar compared to that of 46Ar. The results suggest that correlations, which generally reduce such spectroscopic factors, do not depend strongly on the neutron-proton asymmetry of the nucleus in this isotopic region as was reported in knockout reactions. The present results are consistent with results from systematic studies of transfer reactions but inconsistent with the trends observed in knockout reaction measurements.

  11. Kinetics and spectroscopic observations of atrazine dealkylation on manganese oxides

    SciTech Connect

    Malengreau, N.; Sposito, G.; Cheney, M.A.; Crowley, D.E.

    1997-12-31

    Abiotic transformations of organic pollutants are often neglected in remediation scenarios but nonetheless can contribute significantly to detoxification. Mn oxide minerals are capable of degrading organic pollutants adsorbed to their surfaces by both redox and proton-promoted mechanisms. Concurrently with calorimetric, gas-pressure, chromatographic, and ESR methods, we used ICP, DRS, DRIFT, and FTIR spectroscopies to investigate atrazine degradation on three Mn oxides. We found that N-dealkylation can occur abiotically, leading to the formation of deethylatrazine and deisopropylatrazine. The Mn extractability after degradation of atrazine was highly dependent on the Mn oxide. Extractable Mn increased with time for cryptomelane, was constant for pyrolusite, and remained very low for birnessite. The extractable Mn is Mn(II). UV signatures of atrazine by-products were different from one another and were used to trace degradation products at the Mn oxide surface. Mechanistic interpretation of the in situ reaction kinetics and thermodynamics will be discussed.

  12. Spectroscopic Binaries in the Orion Nebula Cluster and NGC 2264

    NASA Astrophysics Data System (ADS)

    Kounkel, Marina; Hartmann, Lee; Tobin, John J.; Mateo, Mario; Bailey, John I., III; Spencer, Meghin

    2016-04-01

    We examine the spectroscopic binary population for two massive nearby regions of clustered star formation, the Orion Nebula Cluster (ONC) and NGC 2264, supplementing the data presented by Tobin et al. with more recent observations and more extensive analysis. The inferred multiplicity fraction up to 10 au based on these observations is 5.3 ± 1.2% for NGC 2264 and 5.8 ± 1.1% for the ONC; these values are consistent with the distribution of binaries in the field in the relevant parameter range. Eight of the multiple systems in the sample have enough epochs to perform an initial fit for the orbital parameters. Two of these sources are double-lined spectroscopic binaries; for them, we determine the mass ratio. Our reanalysis of the distribution of stellar radial velocities toward these clusters presents a significantly better agreement between stellar and gas kinematics than was previously thought.

  13. The magnetic field of the hot spectroscopic binary HD 5550

    NASA Astrophysics Data System (ADS)

    Neiner, C.; Alecian, E.

    2015-12-01

    HD 5550 is a spectroscopic binary composed of two A stars observed with Narval at TBL in the frame of the BinaMIcS (Binarity and Magnetic Interactions in various classes of Stars) Large Program. One component of the system is found to be an Ap star with a surprisingly weak dipolar field of ˜65 G. The companion is an Am star for which no magnetic field is detected, with a detection threshold on the dipolar field of ˜40 G. The system is tidally locked, the primary component is synchronised with the orbit, but the system is probably not completely circularised yet. This work is only the second detailed study of magnetic fields in a hot short-period spectroscopic binary. More systems are currently being observed with both Narval at TBL and ESPaDOnS at CFHT within the BinaMIcS project, with the goal of understanding how magnetism can impact binary evolution and vice versa.

  14. Spectroscopic imaging in electron microscopy

    SciTech Connect

    Pennycook, Stephen J; Colliex, C.

    2012-01-01

    In the scanning transmission electron microscope, multiple signals can be simultaneously collected, including the transmitted and scattered electron signals (bright field and annular dark field or Z-contrast images), along with spectroscopic signals such as inelastically scattered electrons and emitted photons. In the last few years, the successful development of aberration correctors for the electron microscope has transformed the field of electron microscopy, opening up new possibilities for correlating structure to functionality. Aberration correction not only allows for enhanced structural resolution with incident probes into the sub-angstrom range, but can also provide greater probe currents to facilitate mapping of intrinsically weak spectroscopic signals at the nanoscale or even the atomic level. In this issue of MRS Bulletin, we illustrate the power of the new generation of electron microscopes with a combination of imaging and spectroscopy. We show the mapping of elemental distributions at atomic resolution and also the mapping of electronic and optical properties at unprecedented spatial resolution, with applications ranging from graphene to plasmonic nanostructures, and oxide interfaces to biology.

  15. Spectroscopic ellipsometry study of novel nanostructured transparent conducting oxide structures

    NASA Astrophysics Data System (ADS)

    Khosroabadi, Akram A.; Norwood, R. A.

    2013-02-01

    Spectroscopic ellipsometry has been used to find the optical constants, including refractive index, extinction coefficient, thickness and volume fraction of nanostructured transparent conducting oxides including indium tin oxide (ITO) and indium zinc oxide (IZO). We observed sharp features in the ellipsometry data, with the spectral peaks and positions depending on the nanostructure dimensions and material. A superposition of Lorentzian oscillators and the effective medium approximation has been applied to determine the volume ratio of voids and nanopillars, thereby providing the effective optical constants.

  16. Asiago spectroscopic classification of SN2016aa in PGC 22658

    NASA Astrophysics Data System (ADS)

    Ciabattari, F.; Tomasella, L.; Pastorello, A.; Benetti, S.; Cappellaro, E.; Elias-Rosa, N.; Ochner, P.; Tartaglia, L.; Terreran, G.; Turatto, M.; Briganti, F.; Caimmi, M.; Campaner, P.; Donati, S.; Mazzoni, E.

    2016-02-01

    We report the spectroscopic classification of SN2016aa in PGC 22658 through observations obtained with the 1.82-m Copernico Telescope in Asiago (+ AFOSC; range 340-820 nm, resolution 1.3 nm). A low signal-to-noise spectrogram obtained on Jan 04.97 UT indicates that SN2016aa is a Type II SNe, a few weeks after the explosion.

  17. Spectroscopic investigation of silver in soda-lime glass

    NASA Astrophysics Data System (ADS)

    Borsella, E.; Gonella, F.; Mazzoldi, P.; Quaranta, A.; Battaglin, G.; Polloni, R.

    1998-03-01

    Spectral and time-resolved luminescence of silver in ion-exchanged soda-lime glass are investigated for samples with different Ag concentrations. The evolution of the observed spectroscopic features are correlated with structural changes in the silver environment from a marked ionic position with a weak influence of the surroundings to a configuration characterized by stronger silver-lattice coupling and Ag +-Ag + correlation effects.

  18. Iterative methods for determination of parameters of spectroscopic binaries

    NASA Astrophysics Data System (ADS)

    Dworak, T. Z.

    The paper contains the description of iterative methods for determinations of geometric and physical parameters of spectroscopic binaries, especially for computation of orbit plane inclination i and radii of components, which cannot be determined from observations. These methods are based of some considerations given in the previous paper (Dworak 1975). The methods have been tested using data for eclipsing binaries, taken from the catalogues of Batten et al. (1978) and Koch et al. (1970).

  19. Highlights of the Brazilian Solar Spectroscope (bss)

    NASA Astrophysics Data System (ADS)

    Sawant, Hanumant; Cecatto, José; Meszarosova, Hana; Faria, Claudio; Fernandes, Francisco; Karlicky, Marian; Andrade, Maria

    The digital, decimetric (1000-2500 MHz) Brazilian Solar Spectroscope (BSS) with high time (10- 1000 ms) and frequency (1-10 MHz) resolution is in regular operation since April, 1998, at the National Space Research Institute (INPE) at Sao Jose dos Campos, Brazil. The BSS has now been upgraded with a new digital data acquisition and data processing system. The new version of the BSS has a 14 bit A/D unit which permits improved combination of the observational parameters with a capability to record up to 200 frequency channels available in a selectable frequency range of 1000-2500 MHz. It permits data acquisition up to 5 ms time resolution with a limited number of frequency channels. The software system of the BSS is composed by two distinct modules: The first, data acquisition system provides a flexible Graphical User Interface (GUI) that allows one to choose a number of observational parameters. The second module is the real time visualization system that permits real time visualization of the observed dynamic spectrum and additionally has procedures for visualization and preliminary analysis of the recorded solar spectra. Using the new visualization system, we have realized two new types of dm-radio fine structures: narrow band type III bursts with positive/negative group frequency drift and dots-emissions arranged in zebras and fibers.

  20. Long-Term Photometric and Spectroscopic Variability of V501 Aur

    NASA Astrophysics Data System (ADS)

    Vaňko, M.; Torres, G.; Pribulla, T.; Parimucha, Š.; Krushevska, V.; Neuhäuser, R.; Shugarov, S.; Hambálek, L.'; Kundra, E.; Nedoroščík, J.; Garai, Z.

    2015-07-01

    We present new VRI photometry of V501 Aur obtained between 2007 and 2013 at the Grossschwabhausen (Germany) and Stará Lesná (Slovakia) observatories, as well as spectroscopic obervations from the Harvard-Smithsonian Center for Astrophysics (USA). The spectroscopic observations show it to be a single-lined binary, with a different period (68.8 days) than the one indicated by the photometry (˜55 days). We discuss the possible nature of the system.

  1. Spectroscopic Needs for Imaging Dark Energy Experiments

    DOE PAGESBeta

    Newman, Jeffrey A.; Slosar, Anze; Abate, Alexandra; Abdalla, Filipe B.; Allam, Sahar; Allen, Steven W.; Ansari, Reza; Bailey, Stephen; Barkhouse, Wayne A.; Beers, Timothy C.; et al

    2015-03-15

    Ongoing and near-future imaging-based dark energy experiments are critically dependent upon photometric redshifts (a.k.a. photo-z’s): i.e., estimates of the redshifts of objects based only on flux information obtained through broad filters. Higher-quality, lower-scatter photo-z’s will result in smaller random errors on cosmological parameters; while systematic errors in photometric redshift estimates, if not constrained, may dominate all other uncertainties from these experiments. The desired optimization and calibration is dependent upon spectroscopic measurements for secure redshift information; this is the key application of galaxy spectroscopy for imaging-based dark energy experiments. Hence, to achieve their full potential, imaging-based experiments will require large setsmore » of objects with spectroscopically-determined redshifts, for two purposes: Training: Objects with known redshift are needed to map out the relationship between object color and z (or, equivalently, to determine empirically-calibrated templates describing the rest-frame spectra of the full range of galaxies, which may be used to predict the color-z relation). The ultimate goal of training is to minimize each moment of the distribution of differences between photometric redshift estimates and the true redshifts of objects, making the relationship between them as tight as possible. The larger and more complete our “training set” of spectroscopic redshifts is, the smaller the RMS photo-z errors should be, increasing the constraining power of imaging experiments; Requirements: Spectroscopic redshift measurements for ~30,000 objects over >~15 widely-separated regions, each at least ~20 arcmin in diameter, and reaching the faintest objects used in a given experiment, will likely be necessary if photometric redshifts are to be trained and calibrated with conventional techniques. Larger, more complete samples (i.e., with longer exposure times) can improve photo-z algorithms and reduce

  2. Spectroscopic Needs for Imaging Dark Energy Experiments

    SciTech Connect

    Newman, Jeffrey A.; Slosar, Anze; Abate, Alexandra; Abdalla, Filipe B.; Allam, Sahar; Allen, Steven W.; Ansari, Reza; Bailey, Stephen; Barkhouse, Wayne A.; Beers, Timothy C.; Blanton, Michael R.; Brodwin, Mark; Brownstein, Joel R.; Brunner, Robert J.; Carrasco-Kind, Matias; Cervantes-Cota, Jorge; Chisari, Nora Elisa; Colless, Matthew; Comparat, Johan; Coupon, Jean; Cheu, Elliott; Cunha, Carlos E.; de la Macorra, Alex; Dell’Antonio, Ian P.; Frye, Brenda L.; Gawiser, Eric J.; Gehrels, Neil; Grady, Kevin; Hagen, Alex; Hall, Patrick B.; Hearin, Andrew P.; Hildebrandt, Hendrik; Hirata, Christopher M.; Ho, Shirley; Honscheid, Klaus; Huterer, Dragan; Ivezic, Zeljko; Kneib, Jean -Paul; Kruk, Jeffrey W.; Lahav, Ofer; Mandelbaum, Rachel; Marshall, Jennifer L.; Matthews, Daniel J.; Menard, Brice; Miquel, Ramon; Moniez, Marc; Moos, H. W.; Moustakas, John; Papovich, Casey; Peacock, John A.; Park, Changbom; Rhodes, Jason; Sadeh, Iftach; Schmidt, Samuel J.; Stern, Daniel K.; Tyson, J. Anthony; von der Linden, Anja; Wechsler, Risa H.; Wood-Vasey, W. M.; Zentner, A.

    2015-03-15

    Ongoing and near-future imaging-based dark energy experiments are critically dependent upon photometric redshifts (a.k.a. photo-z’s): i.e., estimates of the redshifts of objects based only on flux information obtained through broad filters. Higher-quality, lower-scatter photo-z’s will result in smaller random errors on cosmological parameters; while systematic errors in photometric redshift estimates, if not constrained, may dominate all other uncertainties from these experiments. The desired optimization and calibration is dependent upon spectroscopic measurements for secure redshift information; this is the key application of galaxy spectroscopy for imaging-based dark energy experiments. Hence, to achieve their full potential, imaging-based experiments will require large sets of objects with spectroscopically-determined redshifts, for two purposes: Training: Objects with known redshift are needed to map out the relationship between object color and z (or, equivalently, to determine empirically-calibrated templates describing the rest-frame spectra of the full range of galaxies, which may be used to predict the color-z relation). The ultimate goal of training is to minimize each moment of the distribution of differences between photometric redshift estimates and the true redshifts of objects, making the relationship between them as tight as possible. The larger and more complete our “training set” of spectroscopic redshifts is, the smaller the RMS photo-z errors should be, increasing the constraining power of imaging experiments; Requirements: Spectroscopic redshift measurements for ~30,000 objects over >~15 widely-separated regions, each at least ~20 arcmin in diameter, and reaching the faintest objects used in a given experiment, will likely be necessary if photometric redshifts are to be trained and calibrated with conventional techniques. Larger, more complete samples (i.e., with longer exposure times) can improve photo-z algorithms and reduce scatter

  3. The opportunities and challenges of multi-site evaluations: lessons from the jail diversion and trauma recovery national cross-site evaluation.

    PubMed

    Stainbrook, Kristin; Penney, Darby; Elwyn, Laura

    2015-06-01

    Multi-site evaluations, particularly of federally funded service programs, pose a special set of challenges for program evaluation. Not only are there contextual differences related to project location, there are often relatively few programmatic requirements, which results in variations in program models, target populations and services. The Jail Diversion and Trauma Recovery-Priority to Veterans (JDTR) National Cross-Site Evaluation was tasked with conducting a multi-site evaluation of thirteen grantee programs that varied along multiple domains. This article describes the use of a mixed methods evaluation design to understand the jail diversion programs and client outcomes for veterans with trauma, mental health and/or substance use problems. We discuss the challenges encountered in evaluating diverse programs, the benefits of the evaluation in the face of these challenges, and offer lessons learned for other evaluators undertaking this type of evaluation. PMID:25723338

  4. Streamlining IRB review in multisite trials through single-study IRB Cooperative Agreements: experience of the Beta-Carotene and Retinol Efficacy Trial (CARET).

    PubMed

    Thornquist, Mark D; Edelstein, Cim; Goodman, Gary E; Omenn, Gilbert S

    2002-02-01

    With their extensive data and specimen repositories, clinical trials are a long-term, valuable resource to health researchers. However, assuring protection of participants' rights can be challenging, particularly when such trials are conducted at multiple sites with multiple Institutional Review Boards (IRBs). One little-used mechanism that can streamline IRB review in multisite trials while maintaining participants' protections is the single-study IRB Cooperative Agreement. This agreement is entirely different from reciprocity agreements between institutions. Beginning in 1996, the Beta-Carotene and Retinol Efficacy Trial established single-study IRB Cooperative Agreements among its performance sites, which reduced the average time to complete IRB approval from over 6 months to 1 month for each of many substudies. We describe our experience and make recommendations for other multisite clinical trials. PMID:11852169

  5. Ultrasound assisted the preparation of 1-butoxy-4-nitrobenzene under a new multi-site phase-transfer catalyst--kinetic study.

    PubMed

    Harikumar, Kuppuswamy; Rajendran, Venugopal

    2014-01-01

    In the present research work deals with the preparation of 1-butoxy-4-nitrobenzene was successfully carried out by 4-nitrophenol with n-butyl bromide using aqueous potassium carbonate and catalyzed by a new multi-site phase-transfer catalyst (MPTC) viz., N(1),N(4)-diethyl-N(1),N(1),N(4),N(4)-tetraisopropylbutane-1,4-diammonium dibromide, under ultrasonic (40 kHz, 300 W) assisted organic solvent condition. The pseudo first-order kinetic equation was applied to describe the overall reaction. Under ultrasound irradiation (40 kHz, 300 W) in a batch reactor, it shows that the overall reaction greatly enhanced with ultrasound irradiation than without ultrasound. The present study provides a method to synthesize nitro aromatic ethers by ultrasound assisted liquid-liquid multi-site phase-transfer catalysis condition. PMID:23948491

  6. The Hubble Spectroscopic Legacy Archive

    NASA Astrophysics Data System (ADS)

    Peeples, Molly S.; Tumlinson, Jason; Fox, Andrew; Aloisi, Alessandra; Ayres, Thomas R.; Danforth, Charles; Fleming, Scott W.; Jenkins, Edward B.; Jedrzejewski, Robert I.; Keeney, Brian A.; Oliveira, Cristina M.

    2016-01-01

    With no future space ultraviolet instruments currently planned, the data from the UV spectrographs aboard the Hubble Space Telescope have a legacy value beyond their initial science goals. The Hubble Spectroscopic Legacy Archive will provide to the community new science-grade combined spectra for all publicly available data obtained by the Cosmic Origins Spectrograph (COS) and the Space Telescope Imaging Spectrograph (STIS). These data will be packaged into "smart archives" according to target type and scientific themes to facilitate the construction of archival samples for common science uses. A new "quick look" capability will make the data easy for users to quickly access, assess the quality of, and download for archival science starting in Cycle 24, with the first generation of these products for the FUV modes of COS available online via MAST in early 2016.

  7. Spectroscopic Studies of Abell Clusters

    NASA Astrophysics Data System (ADS)

    Way, Michael Joseph

    The objectives of this work are to use spectroscopic techniques to accurately categorize galaxies as either HII region star forming galaxies or as Active Galactic Nuclei powered via a black hole, and to use radial velocities and projected positions of galaxies in clusters to obtain the total cluster mass and its distribution. The masses and distributions compare well to X-ray mass measurements. The commonly used Dressler, A., Thompson, I. & Shectman, S. 1985, ApJ, 288, 481 technique for discriminating between Active Galactic Nuclei and HII region galaxies uses the measurement of the equivalent width of the emission lines (OII) 3727 A, H/beta, and (OIII) 5007 A. High quality spectra from 42 galaxies were taken and it is shown that their method is not capable of distinguishing between Active Galactic Nuclei and HII region galaxies. The emission line flux from H/beta, (OIII) 5007 A, (OI) 6300 A, Hα, (NII) 6583 A, and (SII) 6716+6731 A in combination with the method of Veilleux, S. & Osterbrock, D. E. 1987, ApJS, 63, 295 must be used to accurately distinguish between Active Galactic Nuclei and HII region galaxies. Galaxy radial velocities from spectroscopic data and their projected 2-D positions in clusters are used to obtain robust estimates of the total mass and mass distribution in two clusters. The total mass is calculated using the Virial theorem after removing substructure. The mass distribution is estimated via several robust statistical tests for 1-D, 2-D and 3-D structure. It is shown that the derived mass estimates agree well with those found independently from hot X-ray gas emission in clusters.

  8. Spectroscopic Subsystems in Nearby Wide Binaries

    NASA Astrophysics Data System (ADS)

    Tokovinin, Andrei

    2015-12-01

    Radial velocity (RV) monitoring of solar-type visual binaries has been conducted at the CTIO/SMARTS 1.5 m telescope to study short-period systems. The data reduction is described, and mean and individual RVs of 163 observed objects are given. New spectroscopic binaries are discovered or suspected in 17 objects, and for some of them the orbital periods could be determined. Subsystems are efficiently detected even in a single observation by double lines and/or by the RV difference between the components of visual binaries. The potential of this detection technique is quantified by simulation and used for statistical assessment of 96 wide binaries within 67 pc. It is found that 43 binaries contain at least one subsystem, and the occurrence of subsystems is equally probable in either primary or secondary components. The frequency of subsystems and their periods matches the simple prescription proposed by the author. The remaining 53 simple wide binaries with a median projected separation of 1300 AU have an RV difference distribution between their components that is not compatible with the thermal eccentricity distribution f (e) = 2e but rather matches the uniform eccentricity distribution.

  9. Spectroscopic and Interferometric Measurements of Nine K Giant Stars

    NASA Astrophysics Data System (ADS)

    Baines, Ellyn K.; Döllinger, Michaela P.; Guenther, Eike W.; Hatzes, Artie P.; Hrudkovu, Marie; van Belle, Gerard T.

    2016-09-01

    We present spectroscopic and interferometric measurements for a sample of nine K giant stars. These targets are of particular interest because they are slated for stellar oscillation observations. Our improved parameters will directly translate into reduced errors in the final masses for these stars when interferometric radii and asteroseismic densities are combined. Here, we determine each star’s limb-darkened angular diameter, physical radius, luminosity, bolometric flux, effective temperature, surface gravity, metallicity, and mass. When we compare our interferometric and spectroscopic results, we find no systematic offsets in the diameters and the values generally agree within the errors. Our interferometric temperatures for seven of the nine stars are hotter than those determined from spectroscopy with an average difference of about 380 K.

  10. Silicon immersion gratings and their spectroscopic applications

    NASA Astrophysics Data System (ADS)

    Ge, Jian; Zhao, Bo; Powell, Scott; Fletcher, Adam; Wan, Xiaoke; Chang, Liang; Jakeman, Hali; Koukis, Dimitrios; Tanner, David B.; Ebbets, Dennis; Weinberg, Jonathan; Lipscy, Sarah; Nyquist, Rich; Bally, John

    2012-09-01

    Silicon immersion gratings (SIGs) offer several advantages over the commercial echelle gratings for high resolution infrared (IR) spectroscopy: 3.4 times the gain in dispersion or ~10 times the reduction in the instrument volume, a multiplex gain for a large continuous wavelength coverage and low cost. We present results from lab characterization of a large format SIG of astronomical observation quality. This SIG, with a 54.74 degree blaze angle (R1.4), 16.1 l/mm groove density, and 50x86 mm2 grating area, was developed for high resolution IR spectroscopy (R~70,000) in the near IR (1.1-2.5 μm). Its entrance surface was coated with a single layer of silicon nitride antireflection (AR) coating and its grating surface was coated with a thin layer of gold to increase its throughput at 1.1-2.5 μm. The lab measurements have shown that the SIG delivered a spectral resolution of R=114,000 at 1.55 μm with a lab testing spectrograph with a 20 mm diameter pupil. The measured peak grating efficiency is 72% at 1.55 μm, which is consistent with the measurements in the optical wavelengths from the grating surface at the air side. This SIG is being implemented in a new generation cryogenic IR spectrograph, called the Florida IR Silicon immersion grating spectrometer (FIRST), to offer broad-band high resolution IR spectroscopy with R=72,000 at 1.4-1.8 um under a typical seeing condition in a single exposure with a 2kx2k H2RG IR array at the robotically controlled Tennessee State University 2-meter Automatic Spectroscopic Telescope (AST) at Fairborn Observatory in Arizona. FIRST is designed to provide high precision Doppler measurements (~4 m/s) for the identification and characterization of extrasolar planets, especially rocky planets in habitable zones, orbiting low mass M dwarf stars. It will also be used for other high resolution IR spectroscopic observations of such as young stars, brown dwarfs, magnetic fields, star formation and interstellar mediums. An optimally designed

  11. The Spectroscopic Evolution of Nova Cygni 1992

    NASA Astrophysics Data System (ADS)

    Moro-Martin, A.; Garnavich, P. M.; Noriega-Crespo, A.; Alpert, A.

    1996-12-01

    Optical spectroscopic observations of Nova Cygni 1992 spanning 4 years are modeled in this study. The data were obtained primarily with the DAO 1.8m telescope and cover a wavelength range from ~ 3200 - 8000 Angstroms. The observations begin on May 92 (85 days after the outburst) and end on June 1996, i.e. during most of the optically thin evolutionary phase. The spectra were modeled in a relatively straightforward way by using the flux predicted by a photoionization code [1] for most of the emission lines (down to 0.1% of Hβ ) and transforming these numbers into a synthetic spectrum. There are, however, significant differences in the detailed procedure in comparison with similar works [2]. First, the photoionization models were run at a fixed abundance value for the most prominent elements (i.e. H, He, C, O, N, Ne, Fe, etc) over the entire time sequence. Second, the brightest lines, e.g. [Ne V], [Ne III], [O III] and the Balmer lines, were initially used as guide to match the observations. The rest of the spectra, which includes the fainter lines, were then directly predicted by the photoionization code. Considering the complicated structure of the shell [3], the lack of well defined values of its gas density and our limited knowledge of the time evolution of the surface temperature of the photoionization source, the comparison between models and observations agrees remarkably well. It was found that the time evolution of some of the Iron coronal lines, [Fe VII] 6087 Angstroms and [Fe X] 6374 Angstroms, closely follows that of the X-rays [4]. [1] Ferland, G.J 1993, CLOUDY, U. of Kentucky Dept. Phys & Astr. Internal Report. [2] Austin et al. 1992, AJ, 111, 869 [3] Paresce, Livio, Hack & Korista (1995) A&A, 299, 823 [4] Krautter et al. (1996), ApJ, 456, 788

  12. The Sydney Multisite Intervention of LaughterBosses and ElderClowns (SMILE) study: cluster randomised trial of humour therapy in nursing homes

    PubMed Central

    Low, Lee-Fay; Brodaty, Henry; Goodenough, Belinda; Spitzer, Peter; Bell, Jean-Paul; Fleming, Richard; Casey, Anne-Nicole; Liu, Zhixin; Chenoweth, Lynn

    2013-01-01

    Objectives To determine whether humour therapy reduces depression (primary outcome), agitation and behavioural disturbances and improves social engagement and quality-of-life in nursing home residents. Design The Sydney Multisite Intervention of LaughterBosses and ElderClowns study was a single-blind cluster randomised controlled trial of humour therapy. Setting 35 Sydney nursing homes. Participants All eligible residents within geographically defined areas within each nursing home were invited to participate. Intervention Professional ‘ElderClowns’ provided 9–12 weekly humour therapy sessions, augmented by resident engagement by trained staff ‘LaughterBosses’. Controls received usual care. Measurements Depression scores on the Cornell Scale for Depression in Dementia, agitation scores on the Cohen-Mansfield Agitation Inventory, behavioural disturbance scores on the Neuropsychiatric Inventory, social engagement scores on the withdrawal subscale of Multidimensional Observation Scale for Elderly Subjects, and self-rated and proxy-rated quality-of-life scores on a health-related quality-of-life tool for dementia, the DEMQOL. All outcomes were measured at the participant level by researchers blind to group assignment. Randomisation Sites were stratified by size and level of care then assigned to group using a random number generator. Results Seventeen nursing homes (189 residents) received the intervention and 18 homes (209 residents) received usual care. Groups did not differ significantly over time on the primary outcome of depression, or on behavioural disturbances other than agitation, social engagement and quality of life. The secondary outcome of agitation was significantly reduced in the intervention group compared with controls over 26 weeks (time by group interaction adjusted for covariates: p=0.011). The mean difference in change from baseline to 26 weeks in Blom-transformed agitation scores after adjustment for covariates was 0.17 (95% CI 0

  13. Multisite high resolution measurements of carbon monoxide along Greenland ice cores: evidence for in-situ production and potential for atmospheric reconstruction

    NASA Astrophysics Data System (ADS)

    Faïn, Xavier; Chappellaz, Jérôme; Rhodes, Rachael; Stowasser, Christopher; Blunier, Thomas; McConnell, Joseph; Brook, Edward; Desbois, Thibault; Romanini, Daniele

    2014-05-01

    Carbon monoxide (CO) is the principal sink for hydroxyl radicals (OH) in the troposphere. Consequently, changes in atmospheric CO levels can considerably perturb the oxidizing capacity of the atmosphere, affecting mixing ratios of a host of chemical species oxidized by OH, including methane. In addition, CO variations (and changes in its stable isotopic composition) are expected to be good tracers of changes in biomass burning emissions. Investigating past mixing ratios of carbon monoxide is thus a promising approach towards reducing uncertainty related to the past oxidative capacity of the atmosphere and biogeochemical cycling of methane. Recent developments in optical spectrometry (Optical Feedback Cavity Enhanced Absorption Spectrometry, OFCEAS), combined with continuous flow analysis (CFA) systems, allow efficient, precise measurements of CO concentrations in ice cores. Coupling our OFCEAS spectrometer with the CFA melter operated at DRI (Reno, USA) provided the first continuous CO measurements along the NEEM (Greenland) core covering the last 1800 yr at an unprecedented resolution. Although the most recent section of this record (i.e., since 1700 AD) agreed with existing discrete CO measurements from the Eurocore ice core and the deep NEEM firn, it was difficult to interpret in terms of atmospheric CO variation due to high frequency, high amplitudes spikes related to in-situ production (Faïn et al., Climate of the Past Discussion). During a recent 8-week analytical campaign, three different ice archives from Greenland were melted on the DRI CFA and analyzed continuously for CO with the OFCEAS spectrometer: (i) the D4 core (spanning the last 170 yr), (ii) the NEEM core (extending the existing record from 200 AD to 800 BC), and (iii) the Tunu core (spanning the last 1800 yr). Although in-situ production of CO is observed at all sites, these new records reveal different CO patterns and trends. This multisite approach allows us to better characterize the

  14. The Effect of Preoperative Subcutaneous Fat Thickness on Surgical Site Infection Risk in Patients Undergoing Colorectal Surgery: Results of a Multisite, Prospective Cohort Study.

    PubMed

    Nakagawa, Hiromi; Ohno, Kaori; Ikeda, Shunya; Muto, Masaki

    2016-08-01

    Surgical site infection (SSI) is one of the most frequent postoperative complications among patients undergoing elective colorectal surgery. A multisite, prospective cohort study was conducted to investigate whether the thickness of subcutaneous fat (TSF) influences the occurrence of SSI in patients undergoing colorectal surgery. Participants included patients scheduled to receive colorectal laparotomy for colorectal cancer and who were under the care of a wound ostomy continence nurse at 17 participating general hospitals in Japan. Patients were not eligible to participate if they had undergone emergency surgery, reoperation, or laparoscopic surgery. Demographic, wound, and surgical data and American Society of Anesthesiologists (ASA) scale scores were collected and assessed, along with nutritional status, TSF, body mass index, and risk factors for SSI (ie, length of surgery and wound classification). The incidence of SSI and nutritional conditions was assessed weekly for 30 days after surgery. Of the 155 participants (mean age 68.9 ± 10.8 years, 53 [34.2%] of whom were women), 90 (58.1%) underwent rectal surgery, and the remaining 65 underwent colon surgery. Seventy-two (72, 46.5%) of the 155 patients underwent colostomy surgery; 24 (15.5%) developed a SSI. The mean onset of SSI was 7.3 ± 2.9 days after surgery and commonly observed in the stoma group when the ASA score was 3 or higher (P = 0.02). Patients who developed SSI resumed oral dietary intake later than those without SSI (7.4 days versus 4.6 days, P = 0.02). Multivariate analysis indicated TSF >15 mm (P = 0.01), Alb level <3.5 g/dL at postoperative days 14 (P = 0.03) and 21 (P = 0.02), and total protein level <6.8 g/dL at postoperative day 7 (P = 0.02) were statistically significantly correlated with SSI occurrence. These results suggest preoperative TSF and preoperative and postoperative serum albumin levels are independent risk factors for SSI in patients undergoing colorectal surgery, confirming

  15. Spectroscopic study of the extremely fast rotating star 44 Geminorum

    NASA Astrophysics Data System (ADS)

    Iliev, L.; Vennes, S.; Kawka, A.; Kubat, J.; Nemeth, P.; Borisov, G.; KRaus, M.

    Stars with extremely fast rotation represent interesting challenge to modern understanding of the stellar evolution. The reasons why such a spin-up process should occur during the evolution to otherwise normal star are still not well understood. Already in the beginning of the XX century Otto Struve proposed that fast rotation of the group of stars spectroscopically classified as Be could be the main reason for the formation of observed disks of circumstellar material around them. This circumstellar material is responsible for the emission lines observed in the spectrum of Be-stars as well as for the whole complex of spectral and photometrical patterns called in general Be-phenomenon.

  16. The BHIVES collaborative: organization and evaluation of a multisite demonstration of integrated buprenorphine/naloxone and HIV treatment.

    PubMed

    Weiss, Linda; Egan, James E; Botsko, Michael; Netherland, Julie; Fiellin, David A; Finkelstein, Ruth

    2011-03-01

    Substance abuse is associated with poor medical and quality-of-life outcomes among HIV-infected individuals. Although drug treatment may reduce these negative consequences, for many patients, options are limited. Buprenorphine/naloxone, an opioid agonist treatment that can be prescribed in the United States in office-based settings, can be used to expand treatment capacity and integrate substance abuse services into HIV care. Recognizing this potential, the US Health Resources and Services Administration funded the development and implementation of demonstration projects that integrated HIV care and buprenorphine/naloxone treatment at 10 sites across the country. An Evaluation and Technical Assistance Center provided programmatic and clinical support as well as oversight for an evaluation that examined the processes for and outcomes of integrated care. The evaluation included patient-level self-report and chart abstractions as well as provider and site level data collected through surveys and in-depth interviews. Although multisite demonstrations pose implementation and evaluation challenges, our experience demonstrates that these can, in part, be addressed through ongoing communication and technical assistance as well as a comprehensive evaluation design that incorporates multiple research methods and data sources. Although limitations to evaluation findings persist, they may be balanced by the scope and "real-world" context of the initiative. PMID:21317598

  17. Causal Interactions Within a Frontal-Cingulate-Parietal Network During Cognitive Control: Convergent Evidence from a Multisite-Multitask Investigation.

    PubMed

    Cai, Weidong; Chen, Tianwen; Ryali, Srikanth; Kochalka, John; Li, Chiang-Shan R; Menon, Vinod

    2016-05-01

    Cognitive control plays an important role in goal-directed behavior, but dynamic brain mechanisms underlying it are poorly understood. Here, using multisite fMRI data from over 100 participants, we investigate causal interactions in three cognitive control tasks within a core Frontal-Cingulate-Parietal network. We found significant causal influences from anterior insula (AI) to dorsal anterior cingulate cortex (dACC) in all three tasks. The AI exhibited greater net causal outflow than any other node in the network. Importantly, a similar pattern of causal interactions was uncovered by two different computational methods for causal analysis. Furthermore, the strength of causal interaction from AI to dACC was greater on high, compared with low, cognitive control trials and was significantly correlated with individual differences in cognitive control abilities. These results emphasize the importance of the AI in cognitive control and highlight its role as a causal hub in the Frontal-Cingulate-Parietal network. Our results further suggest that causal signaling between the AI and dACC plays a fundamental role in implementing cognitive control and are consistent with a two-stage cognitive control model in which the AI first detects events requiring greater access to cognitive control resources and then signals the dACC to execute load-specific cognitive control processes. PMID:25778346

  18. Multi-site videoconferencing for home-based education of older people with chronic conditions: the Telehealth Literacy Project.

    PubMed

    Banbury, Annie; Parkinson, Lynne; Nancarrow, Susan; Dart, Jared; Gray, Len; Buckley, Jennene

    2014-10-01

    We examined the acceptability of multi-site videoconferencing as a method of providing group education to older people in their homes. There were 9 groups comprising 52 participants (mean age 73 years) with an average of four chronic conditions. Tablet computers or PCs were installed in participant's homes and connected to the Internet by the National Broadband Network (high-speed broad band network) or by the 4G wireless network. A health literacy and self-management programme was delivered by videoconference for 5 weeks. Participants were able to view and interact with all group members and the facilitator on their devices. During the study, 44 group videoconferences were conducted. Evaluation included 16 semi-structured interviews, 3 focus groups and a journal detailing project implementation. The participants reported enjoying home-based group education by videoconference and found the technology easy to use. Using home-based groups via videoconference was acceptable for providing group education, and considered particularly valuable for people living alone and/or with limited mobility. Audio difficulties were the most commonly reported problem. Participants connected with 4G experienced more problems (audio and visual) than participants on the National Broadband Network and those living in multi-dwelling residences reported more problems than those living in single-dwelling residences. Older people with little computer experience can be supported to use telehealth equipment. Telehealth has the potential to improve access to education about chronic disease self-management. PMID:25399994

  19. Child sexual abuse prevention training for childcare professionals: an independent multi-site randomized controlled trial of Stewards of Children.

    PubMed

    Rheingold, Alyssa A; Zajac, Kristyn; Chapman, Jason E; Patton, Meghan; de Arellano, Michael; Saunders, Benjamin; Kilpatrick, Dean

    2015-04-01

    Given the significant rates and deleterious consequences of childhood sexual abuse (CSA), identifying effective primary prevention approaches is a clear priority. There isa growing awareness that childcare professionals (e.g.,teachers, childcare personnel, clergy) are in a unique position to engage in prevention efforts due to high accessibility to children and expertise in child development. However, CSA prevention programs targeting childcare professionals have received insufficient attention. The goal of this study was toc on duct an independent multi-site controlled evaluation of an existing CSA prevention program, Stewards of Children, offered through both in-person and web-based formats. This study included 352 childcare professionals recruited from children’s advocacy centers across three states. Participants were randomly assigned to one of three conditions: (1) inperson training, (2) web-based training, or (3) waitlist control. Dependent variables included CSA knowledge, CSA attitudes,and self-reported CSA preventive behaviors. Results indicated that Stewards impacted knowledge, attitudes, and preventive behaviors. No differences were found between training modalities (i.e., in-person versus web-based) on knowledge and preventive behaviors. Results indicate that brief trainings for childcare professionals may impact CSA prevention efforts. PMID:25015782

  20. A multisite randomized trial of social norms marketing campaigns to reduce college student drinking: a replication failure.

    PubMed

    DeJong, William; Schneider, Shari Kessel; Towvim, Laura Gomberg; Murphy, Melissa J; Doerr, Emily E; Simonsen, Neal R; Mason, Karen E; Scribner, Richard A

    2009-01-01

    A 14-site randomized trial tested the effectiveness of social norms marketing (SNM) campaigns, which present accurate student survey data in order to correct misperceptions of subjective drinking norms and thereby drive down alcohol use. Cross-sectional student surveys were conducted by mail at baseline and at posttest 3 years later. Hierarchical linear modeling was applied to examine multiple drinking outcomes, taking into account the nonindependence of students grouped in the same college. Controlling for other predictors, having a SNM campaign was not significantly associated with lower perceptions of student drinking levels or lower self-reported alcohol consumption. This study failed to replicate a previous multisite randomized trial of SNM campaigns, which showed that students attending institutions with a SNM campaign had a lower relative risk of alcohol consumption than students attending control group institutions (W. DeJong et al. J Stud Alcohol. 2006;67:868-879). Additional research is needed to explore whether SNM campaigns are less effective in campus communities with relatively high alcohol retail outlet density. PMID:19347752

  1. Kidney Injury Molecule-1 Outperforms Traditional Biomarkers of Kidney Injury in Multi-site Preclinical Biomarker Qualification Studies

    PubMed Central

    Vaidya, Vishal S.; Ozer, Josef S.; Frank, Dieterle; Collings, Fitz B.; Ramirez, Victoria; Troth, Sean; Muniappa, Nagaraja; Thudium, Douglas; Gerhold, David; Holder, Daniel J.; Bobadilla, Norma A.; Marrer, Estelle; Perentes, Elias; Cordier, André; Vonderscher, Jacky; Maurer, Gérard; Goering, Peter L.; Sistare, Frank D.; Bonventre, Joseph V.

    2010-01-01

    Kidney toxicity accounts for a significant percentage of morbidity and drug candidate failure. Serum creatinine (SCr) and blood urea nitrogen (BUN) have been used to monitor kidney dysfunction for over a century but these markers are insensitive and non-specific. In multi-site preclinical rat toxicology studies the diagnostic performance of urinary kidney injury molecule-1 (Kim-1) was compared to traditional biomarkers as predictors of kidney tubular histopathologic changes, currently considered the “gold standard” of nephrotoxicity. In multiple models of kidney injury, urinary Kim-1 significantly outperformed SCr and BUN. The area under the receiver operating characteristic curve for Kim-1 was between 0.91 and 0.99 as compared to 0.79 to 0.9 for BUN and 0.73 to 0.85 for SCr. Thus urinary Kim-1 is the first injury biomarker of kidney toxicity qualified by the FDA and EMEA and is expected to significantly improve kidney safety monitoring. PMID:20458318

  2. Robot-assisted upper-limb therapy in acute rehabilitation setting following stroke: Department of Veterans Affairs multisite clinical trial.

    PubMed

    Burgar, Charles G; Lum, Peter S; Scremin, A M Erika; Garber, Susan L; Van der Loos, H F Machiel; Kenney, Deborah; Shor, Peggy

    2011-01-01

    This randomized, controlled, multisite Department of Veterans Affairs clinical trial assessed robot-assisted (RA) upper-limb therapy with the Mirror Image Movement Enabler (MIME) in the acute stroke rehabilitation setting. Hemiparetic subjects (n = 54) received RA therapy using MIME for either up to 15 hours (low-dose) or 30 hours (high-dose) or received up to 15 hours of additional conventional therapy in addition to usual care (control). The primary outcome measure was the Fugl-Meyer Assessment (FMA). The secondary outcome measures were the Functional Independence Measure (FIM), Wolf Motor Function Test, Motor Power, and Ashworth scores at intake, discharge, and 6-month follow-up. Mean duration of study treatment was 8.6, 15.8, and 9.4 hours for the low-dose, high-dose, and control groups, respectively. Gains in the primary outcome measure were not significantly different between groups at follow-up. Significant correlations were found at discharge between FMA gains and the dose and intensity of RA. Intensity also correlated with FMA gain at 6 months. The high-dose group had greater FIM gains than controls at discharge and greater tone but no difference in FIM changes compared with low-dose subjects at 6 months. As used during acute rehabilitation, motor-control changes at follow-up were no less with MIME than with additional conventional therapy. Intensity of training with MIME was positively correlated with motor-control gains. PMID:21674393

  3. Multisite-specific archaeosine tRNA-guanine transglycosylase (ArcTGT) from Thermoplasma acidophilum, a thermo-acidophilic archaeon

    PubMed Central

    Kawamura, Takuya; Hirata, Akira; Ohno, Satoshi; Nomura, Yuichiro; Nagano, Tomoko; Nameki, Nobukazu; Yokogawa, Takashi; Hori, Hiroyuki

    2016-01-01

    Archaeosine (G+), which is found only at position 15 in many archaeal tRNA, is formed by two steps, the replacement of the guanine base with preQ0 by archaeosine tRNA-guanine transglycosylase (ArcTGT) and the subsequent modification of preQ0 to G+ by archaeosine synthase. However, tRNALeu from Thermoplasma acidophilum, a thermo-acidophilic archaeon, exceptionally has two G+13 and G+15 modifications. In this study, we focused on the biosynthesis mechanism of G+13 and G+15 modifications in this tRNALeu. Purified ArcTGT from Pyrococcus horikoshii, for which the tRNA recognition mechanism and structure were previously characterized, exchanged only the G15 base in a tRNALeu transcript with 14C-guanine. In contrast, T. acidophilum cell extract exchanged both G13 and G15 bases. Because T. acidophilum ArcTGT could not be expressed as a soluble protein in Escherichia coli, we employed an expression system using another thermophilic archaeon, Thermococcus kodakarensis. The arcTGT gene in T. kodakarensis was disrupted, complemented with the T. acidophilum arcTGT gene, and tRNALeu variants were expressed. Mass spectrometry analysis of purified tRNALeu variants revealed the modifications of G+13 and G+15 in the wild-type tRNALeu. Thus, T. acidophilum ArcTGT has a multisite specificity and is responsible for the formation of both G+13 and G+15 modifications. PMID:26721388

  4. Application of microseismic technology to hydraulic fracture diagnostics: GRI/DOE Field Fracturing Multi-Sites Project

    SciTech Connect

    Wilmer, R.; Warpinski, N.R.; Wright, T.B.; Branagan, P.T.; Fix, J.E.

    1995-06-01

    The objective of the Field Fracturing Multi-Sites Project (M-Site) is to conduct field experiments and analyze data that will result in definitive determinations of hydraulic fracture dimensions using remote well and treatment well diagnostic techniques. In addition, experiments will be conducted to provide data that will resolve significant unknowns with regard to hydraulic fracture modeling, fracture fluid rheology and fracture treatment design. These experiments will be supported by a well-characterized subsurface environment as well as surface facilities and equipment conducive to acquiring high-quality data. It is anticipated that the project`s research advancements will provide a foundation for a fracture diagnostic service industry and hydraulic fracture optimization based on measured fracture response. The M-Site Project is jointly sponsored by the Gas Research Institute (GRI) and the US Department of Energy (DOE). The site developed for M-Site hydraulic fracture experimentation is the former DOE Multiwell Experiment (MWX) site located near Rifle, Colorado. The MWX project drilled three closely-spaced wells (MWX-1, MWX-2 and MWX-3) which were the basis for extensive reservoir analyses and tight gas sand characterizations in the blanket and lenticular sandstone bodies of the Mesaverde Group. The research results and background knowledge gained from the MWX project are directly applicable to research in the current M-Site Project.

  5. A Meta-heuristically Approach of the Spatial Assignment Problem of Human Resources in Multi-sites Enterprise

    NASA Astrophysics Data System (ADS)

    Said, Tkatek; Otman, Abdoun; Jaafar, Abouchabaka; Najat, Rafalia

    2013-09-01

    The aim of this work is to present a meta-heuristically approach of the spatial assignment problem of human resources in multi-sites enterprise. Usually, this problem consists to move employees from one site to another based on one or more criteria. Our goal in this new approach is to improve the quality of service and performance of all sites with maximizing an objective function under some managers imposed constraints. The formulation presented here of this problem coincides perfectly with a Combinatorial Optimization Problem (COP) which is in the most cases NP-hard to solve optimally. To avoid this difficulty, we have opted to use a meta-heuristic popular method, which is the genetic algorithm, to solve this problem in concrete cases. The results obtained have shown the effectiveness of our approach, which remains until now very costly in time. But the reduction of the time can be obtained by different ways that we plan to do in the next work.

  6. Control of microtubule dynamics by oncoprotein 18: dissection of the regulatory role of multisite phosphorylation during mitosis.

    PubMed Central

    Larsson, N; Marklund, U; Gradin, H M; Brattsand, G; Gullberg, M

    1997-01-01

    Oncoprotein 18 (Op18; also termed p19, 19K, metablastin, stathmin, and prosolin) is a conserved protein that regulates microtubule (MT) dynamics. Op18 is multisite phosphorylated on four Ser residues during mitosis; two of these Ser residues, Ser-25 and Ser-38, are targets for cyclin-dependent protein kinases (CDKs), and the other two Ser residues, Ser-16 and Ser-63, are targets for an unidentified protein kinase. Mutations of the two CDK sites have recently been shown to result in a mitotic block caused by destabilization of MTs. To understand the role of Op18 in regulation of MT dynamics during mitosis, in this study we dissected the functions of all four phosphorylation sites of Op18 by combining genetic, morphological, and biochemical analyses. The data show that all four phosphorylation sites are involved in switching off Op18 activity during mitosis, an event that appears to be essential for formation of the spindle during metaphase. However, the mechanisms by which specific sites down-regulate Op18 activity differ. Hence, dual phosphorylation on the CDK sites Ser-25 and Ser-38 appears to be required for phosphorylation of Ser-16 and Ser-63; however, by themselves, the CDK sites are of only minor importance in direct regulation of Op18 activity. Subsequent phosphorylation of either Ser-16, Ser-63, or both efficiently switches off Op18 activity. PMID:9271428

  7. Tissue classification of large-scale multi-site MR data using fuzzy k-nearest neighbor method

    NASA Astrophysics Data System (ADS)

    Ghayoor, Ali; Paulsen, Jane S.; Kim, Regina E. Y.; Johnson, Hans J.

    2016-03-01

    This paper describes enhancements to automate classification of brain tissues for multi-site degenerative magnetic resonance imaging (MRI) data analysis. Processing of large collections of MR images is a key research technique to advance our understanding of the human brain. Previous studies have developed a robust multi-modal tool for automated tissue classification of large-scale data based on expectation maximization (EM) method initialized by group-wise prior probability distributions. This work aims to augment the EM-based classification using a non-parametric fuzzy k-Nearest Neighbor (k-NN) classifier that can model the unique anatomical states of each subject in the study of degenerative diseases. The presented method is applicable to multi-center heterogeneous data analysis and is quantitatively validated on a set of 18 synthetic multi-modal MR datasets having six different levels of noise and three degrees of bias-field provided with known ground truth. Dice index and average Hausdorff distance are used to compare the accuracy and robustness of the proposed method to a state-of-the-art classification method implemented based on EM algorithm. Both evaluation measurements show that presented enhancements produce superior results as compared to the EM only classification.

  8. Spectroscopic Orbits for Kepler FOV Eclipsing Binaries

    NASA Astrophysics Data System (ADS)

    Matson, Rachel A.; Gies, Douglas R.; Williams, Stephen J.; Guo, Zhao

    2013-02-01

    We are currently involved in a four year program of precise eclipsing binary photometry with the NASA Kepler Observatory. Our goal is to search for variations in minimum light timing for intermediate mass eclipsing binaries. Such periodic variations will reveal the reflex motion caused by any distant, low mass object that orbits the close binary. it Kepler's unprecedented accuracy and continuous observations provide a unique opportunity to detect the low mass companions that are predicted to result from the angular momentum of the natal cloud. The goal of this proposal is to obtain blue spectra of short period (0.9-6d) eclipsing binaries, derive radial velocities, and produce a double-lined spectroscopic orbit (as well as estimates of the stellar effective temperatures, gravities, and metallicities). Combined with the it Kepler light curve, we will determine very accurate masses and radii for the members of the close binary, which will yield the mass-inclination product M_3 sin i for any companions detected by light travel time or other effects. An extended sample of eclipsing binaries with longer periods (up to 50d) is now being investigated to test whether the presence of a tertiary companion declines with increasing period. We propose to obtain a single spectrum at quadrature for the brightest 48 stars in this expanded sample to characterize the effective temperatures and total mass contained in these systems.

  9. IMPROVED SPECTROSCOPIC PARAMETERS FOR TRANSITING PLANET HOSTS

    SciTech Connect

    Torres, Guillermo; Holman, Matthew J.; Carter, Joshua A.; Fischer, Debra A.; Sozzetti, Alessandro; Buchhave, Lars A.; Winn, Joshua N.

    2012-10-01

    We report homogeneous spectroscopic determinations of the effective temperature, metallicity, and projected rotational velocity for the host stars of 56 transiting planets. Our analysis is based primarily on the stellar parameter classification (SPC) technique. We investigate systematic errors by examining subsets of the data with two other methods that have often been used in previous studies (Spectroscopy Made Easy (SME) and MOOG). The SPC and SME results, both based on comparisons between synthetic spectra and actual spectra, show strong correlations between T{sub eff}, [Fe/H], and log g when solving for all three quantities simultaneously. In contrast the MOOG results, based on a more traditional curve-of-growth approach, show no such correlations. To combat the correlations and improve the accuracy of the temperatures and metallicities, we repeat the SPC analysis with a constraint on log g based on the mean stellar density that can be derived from the analysis of the transit light curves. Previous studies that have not taken advantage of this constraint have been subject to systematic errors in the stellar masses and radii of up to 20% and 10%, respectively, which can be larger than other observational uncertainties, and which also cause systematic errors in the planetary mass and radius.

  10. Monitoring spectroscopic binaries in anticipation of Gaia

    NASA Astrophysics Data System (ADS)

    Pourbaix, Dimitri; Halbwachs, Jean-Louis; Arenou, Frederic

    2015-08-01

    For several already known spectroscopic binaries, it is anticipated that Gaia will provide an exquisite astrometric orbit of the photocenter. In case of double-lined spectroscopic binaries, the orbital inclination supplied by Gaia will lead to the mass of both components.. For those masses to be useful, an accuracy of 2-3% is required. This can only be achieved if the spectroscopic orbit is very accurate too. A long term monitoring of good spectroscopic candidates in on going on Sophie at the Observatory of Haute Provence and on Hermes on the Mercator telescope in La Palma. For some of these systems, we have already derived a definitive SB2 orbital solution while, for others, the secondary remains unreachable. We present these new solutions in conjunction with the possible impact on the Hipparcos astrometric solution.

  11. Asiago spectroscopic classification of AT2016bry

    NASA Astrophysics Data System (ADS)

    Ochner, P.; Tinella, V.; Righetti, G. L.; Belligoli, R.; Castellani, F.; Pastorello, A.; Cappellaro, E.; Benetti, S.; Tomasella, L.; Elias-Rosa, N.; Tartaglia, L.; Terreran, G.; Turatto, M.

    2016-05-01

    The Asiago Transient Classification Program (Tomasella et al. 2014, AN, 335, 841) reports the spectroscopic classification of AT2016bry, discovered by V. Tinella in UGC 11635, and preliminary photometric follow-up.

  12. Asiago spectroscopic classification of AT2016ajo

    NASA Astrophysics Data System (ADS)

    Terreran, G.; Pastorello, A.; Benetti, S.; Cappellaro, E.; Elias-Rosa, N.; Ochner, P.; Tartaglia, L.; Tomasella, L.; Turatto, M.

    2016-03-01

    The Asiago Transient Classification Program (Tomasella et al. 2014, AN, 335, 841) reports the spectroscopic classification of AT2016ajo, discovered by Y. Ding, W. Gao and X. Gao in an anonymous galaxy near UGC 11344.

  13. CSP Spectroscopic Classification of LSQ16oi

    NASA Astrophysics Data System (ADS)

    Morrell, N.; Phillips, M.; Lira, P.; Ellman, N.; Baltay, C.; Rabinowitz, D.; Rostami, S.; Hsiao, E. Y.

    2016-02-01

    We report the spectroscopic classification of a La Silla-QUEST (LSQ) supernova (Baltay et al. 2013, PASP, 125, 683) taken using WFCCD on the 2.5-m du Pont Telescope as part of the Carnegie Supernova Project (CSP).

  14. Fast Hadamard Spectroscopic Imaging Techniques

    NASA Astrophysics Data System (ADS)

    Goelman, G.

    1994-07-01

    Fast Hadamard spectroscopic imaging (HSI) techniques are presented. These techniques combine transverse and longitudinal encoding to obtain multiple-volume localization. The fast techniques are optimized for nuclei with short T2 and long T1 relaxation times and are therefore suitable for in vivo31P spectroscopy. When volume coils are used in fast HSI techniques, the signal-to-noise ratio per unit time (SNRT) is equal to the SNRT in regular HSI techniques. When surface coils are used, fast HSI techniques give significant improvement of SNRT over conventional HSI. Several fast techniques which are different in total experimental time and pulse demands are presented. When the number of acquisitions in a single repetition time is not higher than two, fast HSI techniques can be used with surface coils and the B1 inhomogeneity does not affect the localization. Surface-coil experiments on phantoms and on human calf muscles in vivo are presented. In addition, it is shown that the localization obtained by the HSI techniques are independent of the repetition times.

  15. SDSS spectroscopic survey of stars

    SciTech Connect

    Ivezic, Zeljko; Schlegel, D.; Uomoto, A.; Bond, N.; Beers, T.; Allende Prieto, C.; Wilhelm, R.; Lee, Y.Sun; Sivarani, T.; Juric, M.; Lupton, R.; /Washington U., Seattle, Astron. Dept. /LBL, Berkeley /Johns Hopkins U. /Princeton U. /Michigan State U. /Texas U. /Texas Tech. /UC, Santa Cruz /Fermilab /Naval Observ., Flagstaff /Drexel U.

    2007-01-01

    In addition to optical photometry of unprecedented quality, the Sloan Digital Sky Survey (SDSS) is also producing a massive spectroscopic database. They discuss determination of stellar parameters, such as effective temperature, gravity and metallicity from SDSS spectra, describe correlations between kinematics and metallicity, and study their variation as a function of the position in the Galaxy. They show that stellar parameter estimates by Beers et al. show a good correlation with the position of a star in the g-r vs. u-g color-color diagram, thereby demonstrating their robustness as well as a potential for photometric parameter estimation methods. Using Beers et al. parameters, they find that the metallicity distribution of the Milky Way stars at a few kpc from the galactic plane is bimodal with a local minimum at [Z/Z{sub {circle_dot}}] {approx} -1.3. The median metallicity for the low-metallicity [Z/Z{sub {circle_dot}}] < =1.3 subsample is nearly independent of Galactic cylindrical coordinates R and z, while it decreases with z for the high-metallicity [Z/Z{sub {circle_dot}}] > -1.3 sample. they also find that the low-metallicity sample has {approx} 2.5 times larger velocity dispersion and that it does not rotate (at the {approx} 10 km/s level), while the rotational velocity of the high-metallicity sample decreases smoothly with the height above the galactic plane.

  16. SDSS spectroscopic survey of stars.

    NASA Astrophysics Data System (ADS)

    Ivezić, Ž.; Schlegel, D.; Uomoto, A.; Bond, N.; Beers, T.; Allende Prieto, C.; Wilhelm, R.; Lee, Y. Sun; Sivarani, T.; Jurić, M.; Lupton, R.; Rockosi, C.; Knapp, G.; Gunn, J.; Yanny, B.; Jester, S.; Kent, S.; Pier, J.; Munn, J.; Richards, G.; Newberg, H.; Blanton, M.; Eisenstein, D.; Hawley, S.; Anderson, S.; Harris, H.; Kiuchi, F.; Chen, A.; Bushong, J.; Sohi, H.; Haggard, D.; Kimball, A.; Barentine, J.; Brewington, H.; Harvanek, M.; Kleinman, S.; Krzesinski, J.; Long, D.; Nitta, A.; Snedden, S.; SDSS Collaboration

    In addition to optical photometry of unprecedented quality, the Sloan Digital Sky Survey (SDSS) is also producing a massive spectroscopic database. We discuss determination of stellar parameters, such as effective temperature, gravity and metallicity from SDSS spectra, describe correlations between kinematics and metallicity, and study their variation as a function of the position in the Galaxy. We show that stellar parameter estimates by Beers et al. show a good correlation with the position of a star in the g-r vs. u-g color-color diagram, thereby demonstrating their robustness as well as a potential for photometric parameter estimation methods. Using Beers et al. parameters, we find that the metallicity distribution of the Milky Way stars at a few kpc from the galactic plane is bimodal with a local minimum at [Z/Z_⊙] ˜ -1.3. The median metallicity for the low-metallicity [Z/Z_⊙]< -1.3 subsample is nearly independent of Galactic cylindrical coordinates R and z, while it decreases with z for the high-metallicity [Z/Z_⊙]> -1.3 sample. We also find that the low-metallicity sample has ˜2.5 times larger velocity dispersion and that it does not rotate (at the ˜10 km/s level), while the rotational velocity of the high-metallicity sample decreases smoothly with the height above the galactic plane.

  17. Spectroscopic studies of copper enzymes

    SciTech Connect

    Dooley, D.M.; Moog, R.; Zumft, W.; Koenig, S.H.; Scott, R.A.; Cote, C.E.; McGuirl, M.

    1986-05-01

    Several spectroscopic methods, including absorption, circular dichroism (CD), magnetic CD (MCD), X-ray absorption, resonance Raman, EPR, NMR, and quasi-elastic light-scattering spectroscopy, have been used to probe the structures of copper-containing amine oxidases, nitrite reductase, and nitrous oxide reductase. The basic goals are to determine the copper site structure, electronic properties, and to generate structure-reactivity correlations. Collectively, the results on the amine oxidases permit a detailed model for the Cu(II) sites in these enzymes to be constructed that, in turn, rationalizes the ligand-binding chemistry. Resonance Raman spectra of the phenylhydrazine and 2,4-dinitrophenyl-hydrazine derivatives of bovine plasma amine oxidase and models for its organic cofactor, e.g. pyridoxal, methoxatin, are most consistent with methoxatin being the intrinsic cofactor. The structure of the Cu(I) forms of the amine oxidases have been investigated by X-ray absorption spectroscopy (XAS); the copper coordination geometry is significantly different in the oxidized and reduced forms. Some anomalous properties of the amine oxidases in solution are explicable in terms of their reversible aggregation, which the authors have characterized via light scattering. Nitrite and nitrous oxide reductases display several novel spectral properties. The data suggest that new types of copper sites are present.

  18. Vibrational spectroscopic characterization of fluoroquinolones

    NASA Astrophysics Data System (ADS)

    Neugebauer, U.; Szeghalmi, A.; Schmitt, M.; Kiefer, W.; Popp, J.; Holzgrabe, U.

    2005-05-01

    Quinolones are important gyrase inhibitors. Even though they are used as active agents in many antibiotics, the detailed mechanism of action on a molecular level is so far not known. It is of greatest interest to shed light on this drug-target interaction to provide useful information in the fight against growing resistances and obtain new insights for the development of new powerful drugs. To reach this goal, on a first step it is essential to understand the structural characteristics of the drugs and the effects that are caused by the environment in detail. In this work we report on Raman spectroscopical investigations of a variety of gyrase inhibitors (nalidixic acid, oxolinic acid, cinoxacin, flumequine, norfloxacin, ciprofloxacin, lomefloxacin, ofloxacin, enoxacin, sarafloxacin and moxifloxacin) by means of micro-Raman spectroscopy excited with various excitation wavelengths, both in the off-resonance region (532, 633, 830 and 1064 nm) and in the resonance region (resonance Raman spectroscopy at 244, 257 and 275 nm). Furthermore DFT calculations were performed to assign the vibrational modes, as well as for an identification of intramolecular hydrogen bonding motifs. The effect of small changes in the drug environment was studied by adding successively small amounts of water until physiological low concentrations of the drugs in aqueous solution were obtained. At these low concentrations resonance Raman spectroscopy proved to be a useful and sensitive technique. Supplementary information was obtained from IR and UV/vis spectroscopy.

  19. Spectroscopic characterization of visbreaking tars

    SciTech Connect

    Scotti, R.; Clericuzio, M.; Pirovano, C.

    1995-12-31

    Visbreaking (VB) is a thermal cracking process, widely used in the refineries of Western Europe to obtain distillates (gasoil, naphtha) from a petroleum residue (feedstock). The visbroken residue (tar) is used to produce fuel oil, after addition of the appropriate amounts of cutter-stock. Even if the highest conversion of feedstock would be desirable, the severity of the VB process is limited by the stability of the resulting VB tars. The stability index (SI) here employed is: SI = I + V{sub cet}, where V{sub cet} is the maximum amount of n-cetane, expressed as ml of cetane for g of sample, that can be added before the flocculation of asphaltenes starts. VB tars having SI<1.1 are considered to be unstable and cannot be used in the preparation of fuel oils with the appropriate specifications. Several papers can be found in the literature dealing with the molecular changes occuring during the VB process. The present paper is aimed at verifying the amount of information that can be extracted from optical spectroscopies and, in particular, the possibility of directly monitoring the physico-chemical modifications caused by VB process. To this purpose a series of VB tars, produced from a single feedstock at different severities, were investigated by a number of spectroscopic techniques, viz.: NIR; UV-Vis; Fluorescence; {sup 1}H and {sup 13}C NUR, EPR.

  20. Combining spectroscopic and photometric surveys: Same or different sky?

    NASA Astrophysics Data System (ADS)

    Eriksen, Martin; Gaztañaga, Enrique

    2015-08-01

    This paper looks at the combined constraints from a photometric and spectroscopic survey. These surveys will measure cosmology using weak lensing (WL), galaxy clustering, baryon acoustic oscillations (BAO) and redshift space distortions (RSD). We find, contrary to some findings in the recent literature, that overlapping surveys can give important benefits when measuring dark energy. We therefore try to clarify the status of this issue with a full forecast of two stage-IV surveys using a new approach to properly account for covariance between the different probes in the overlapping samples. The benefit of the overlapping survey can be traced back to two factors: additional observables and sample variance cancellation. Both needs to be taken into account and contribute equally when combining 3D power spectrum and 2D correlations for lensing. With an analytic example we also illustrate that for optimal constraints, one should minimize the (Pearson) correlation coefficient between cosmological and nuisance parameters and maximize the one among nuisance parameters (e.g. galaxy bias) in the two samples. This can be achieved by increasing the overlap between the spectroscopic and photometric surveys. We show how BAO, WL and RSD contribute to this benefit and also look at some other survey designs, such as photometric redshift errors and spectroscopic density.