Sample records for n-6 registration statement

  1. 17 CFR 274.11d - Form N-6, registration statement of separate accounts organized as unit investment trusts that...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... variable life insurance policies. Form N-6 shall be used as the registration statement to be filed pursuant... insurance policies to register as unit investment trusts. This form shall also be used for registration... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Form N-6, registration...

  2. 17 CFR 274.14 - Form N-8B-4, registration statements of face-amount certificate companies.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... statements of face-amount certificate companies. 274.14 Section 274.14 Commodity and Securities Exchanges... Registration Statements § 274.14 Form N-8B-4, registration statements of face-amount certificate companies. This form shall be used for registration statements of face-amount certificate companies registered...

  3. 17 CFR 274.14 - Form N-8B-4, registration statements of face-amount certificate companies.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... statements of face-amount certificate companies. 274.14 Section 274.14 Commodity and Securities Exchanges... Registration Statements § 274.14 Form N-8B-4, registration statements of face-amount certificate companies. This form shall be used for registration statements of face-amount certificate companies registered...

  4. 17 CFR 274.14 - Form N-8B-4, registration statements of face-amount certificate companies.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... statements of face-amount certificate companies. 274.14 Section 274.14 Commodity and Securities Exchanges... Registration Statements § 274.14 Form N-8B-4, registration statements of face-amount certificate companies. This form shall be used for registration statements of face-amount certificate companies registered...

  5. 17 CFR 274.14 - Form N-8B-4, registration statements of face-amount certificate companies.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... statements of face-amount certificate companies. 274.14 Section 274.14 Commodity and Securities Exchanges... Registration Statements § 274.14 Form N-8B-4, registration statements of face-amount certificate companies. This form shall be used for registration statements of face-amount certificate companies registered...

  6. 17 CFR 274.14 - Form N-8B-4, registration statements of face-amount certificate companies.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... statements of face-amount certificate companies. 274.14 Section 274.14 Commodity and Securities Exchanges... Registration Statements § 274.14 Form N-8B-4, registration statements of face-amount certificate companies. This form shall be used for registration statements of face-amount certificate companies registered...

  7. 17 CFR 239.15A - Form N-1A, registration statement of open-end management investment companies.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... statement of open-end management investment companies. 239.15A Section 239.15A Commodity and Securities... Registration Statements § 239.15A Form N-1A, registration statement of open-end management investment companies... management investment companies other than separate accounts of insurance companies registered under the...

  8. 17 CFR 274.5 - Form N-5, for registration statement of small business investment company under the Securities...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Form N-5, for registration statement of small business investment company under the Securities Act of 1933 and the Investment Company...-5, for registration statement of small business investment company under the Securities Act of 1933...

  9. 17 CFR 270.8b-16 - Amendments to registration statement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... (CONTINUED) RULES AND REGULATIONS, INVESTMENT COMPANY ACT OF 1940 § 270.8b-16 Amendments to registration statement. (a) Every registered management investment company which is required to file a semi-annual report... management investment company whose registration statement was filed on Form N-2; provided that the following...

  10. 28 CFR 10.2 - Language of registration statement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 1 2011-07-01 2011-07-01 false Language of registration statement. 10.2... ON ACTIVITIES WITHIN THE UNITED STATES Registration Statement § 10.2 Language of registration statement. Registration statements must be in English if possible. If in a foreign language they must be...

  11. 17 CFR 239.17c - Form N-6, registration statement for separate accounts organized as unit investment trusts that...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... insurance policies. Form N-6 shall be used for registration under the Securities Act of 1933 of securities... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Form N-6, registration... policies. 239.17c Section 239.17c Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION...

  12. The European Federation of Organisations for Medical Physics Policy Statement No. 6.1: Recommended Guidelines on National Registration Schemes for Medical Physicists.

    PubMed

    Christofides, Stelios; Isidoro, Jorge; Pesznyak, Csilla; Bumbure, Lada; Cremers, Florian; Schmidt, Werner F O

    2016-01-01

    This EFOMP Policy Statement is an update of Policy Statement No. 6 first published in 1994. The present version takes into account the European Union Parliament and Council Directive 2013/55/EU that amends Directive 2005/36/EU on the recognition of professional qualifications and the European Union Council Directive 2013/59/EURATOM laying down the basic safety standards for protection against the dangers arising from exposure to ionising radiation. The European Commission Radiation Protection Report No. 174, Guidelines on Medical Physics Expert and the EFOMP Policy Statement No. 12.1, Recommendations on Medical Physics Education and Training in Europe 2014, are also taken into consideration. The EFOMP National Member Organisations are encouraged to update their Medical Physics registration schemes where these exist or to develop registration schemes taking into account the present version of this EFOMP Policy Statement (Policy Statement No. 6.1"Recommended Guidelines on National Registration Schemes for Medical Physicists"). Copyright © 2016. Published by Elsevier Ltd.

  13. 17 CFR 274.11b - Form N-3, registration statement of separate accounts organized as management investment companies.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... statement of separate accounts organized as management investment companies. 274.11b Section 274.11b... accounts organized as management investment companies. Form N-3 shall be used as the registration statement... offer variable annuity contracts to register as management investment companies. This form shall also be...

  14. 17 CFR 239.17a - Form N-3, registration statement for separate accounts organized as management investment companies.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... statement for separate accounts organized as management investment companies. 239.17a Section 239.17a... accounts organized as management investment companies. Form N-3 shall be used for registration under the... register under the Investment Company Act of 1940 as management investment companies, and certain other...

  15. 17 CFR 270.8b-5 - Time of filing original registration statement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Time of filing original registration statement. 270.8b-5 Section 270.8b-5 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... original registration statement. An investment company shall file a registration statement with the...

  16. 28 CFR 12.25 - Amended registration statement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 1 2012-07-01 2012-07-01 false Amended registration statement. 12.25 Section 12.25 Judicial Administration DEPARTMENT OF JUSTICE REGISTRATION OF CERTAIN PERSONS HAVING KNOWLEDGE OF FOREIGN ESPIONAGE, COUNTERESPIONAGE, OR SABOTAGE MATTERS UNDER THE ACT OF AUGUST 1, 1956 § 12...

  17. 28 CFR 12.25 - Amended registration statement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 1 2013-07-01 2013-07-01 false Amended registration statement. 12.25 Section 12.25 Judicial Administration DEPARTMENT OF JUSTICE REGISTRATION OF CERTAIN PERSONS HAVING KNOWLEDGE OF FOREIGN ESPIONAGE, COUNTERESPIONAGE, OR SABOTAGE MATTERS UNDER THE ACT OF AUGUST 1, 1956 § 12...

  18. 28 CFR 12.23 - Deficient registration statement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 1 2012-07-01 2012-07-01 false Deficient registration statement. 12.23 Section 12.23 Judicial Administration DEPARTMENT OF JUSTICE REGISTRATION OF CERTAIN PERSONS HAVING KNOWLEDGE OF FOREIGN ESPIONAGE, COUNTERESPIONAGE, OR SABOTAGE MATTERS UNDER THE ACT OF AUGUST 1, 1956 § 12...

  19. 28 CFR 12.25 - Amended registration statement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 1 2014-07-01 2014-07-01 false Amended registration statement. 12.25 Section 12.25 Judicial Administration DEPARTMENT OF JUSTICE REGISTRATION OF CERTAIN PERSONS HAVING KNOWLEDGE OF FOREIGN ESPIONAGE, COUNTERESPIONAGE, OR SABOTAGE MATTERS UNDER THE ACT OF AUGUST 1, 1956 § 12...

  20. 28 CFR 12.25 - Amended registration statement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Amended registration statement. 12.25 Section 12.25 Judicial Administration DEPARTMENT OF JUSTICE REGISTRATION OF CERTAIN PERSONS HAVING KNOWLEDGE OF FOREIGN ESPIONAGE, COUNTERESPIONAGE, OR SABOTAGE MATTERS UNDER THE ACT OF AUGUST 1, 1956 § 12...

  1. 28 CFR 12.25 - Amended registration statement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 1 2011-07-01 2011-07-01 false Amended registration statement. 12.25 Section 12.25 Judicial Administration DEPARTMENT OF JUSTICE REGISTRATION OF CERTAIN PERSONS HAVING KNOWLEDGE OF FOREIGN ESPIONAGE, COUNTERESPIONAGE, OR SABOTAGE MATTERS UNDER THE ACT OF AUGUST 1, 1956 § 12...

  2. 28 CFR 12.23 - Deficient registration statement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 1 2014-07-01 2014-07-01 false Deficient registration statement. 12.23 Section 12.23 Judicial Administration DEPARTMENT OF JUSTICE REGISTRATION OF CERTAIN PERSONS HAVING KNOWLEDGE OF FOREIGN ESPIONAGE, COUNTERESPIONAGE, OR SABOTAGE MATTERS UNDER THE ACT OF AUGUST 1, 1956 § 12...

  3. 28 CFR 12.23 - Deficient registration statement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 1 2013-07-01 2013-07-01 false Deficient registration statement. 12.23 Section 12.23 Judicial Administration DEPARTMENT OF JUSTICE REGISTRATION OF CERTAIN PERSONS HAVING KNOWLEDGE OF FOREIGN ESPIONAGE, COUNTERESPIONAGE, OR SABOTAGE MATTERS UNDER THE ACT OF AUGUST 1, 1956 § 12...

  4. 28 CFR 12.23 - Deficient registration statement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Deficient registration statement. 12.23 Section 12.23 Judicial Administration DEPARTMENT OF JUSTICE REGISTRATION OF CERTAIN PERSONS HAVING KNOWLEDGE OF FOREIGN ESPIONAGE, COUNTERESPIONAGE, OR SABOTAGE MATTERS UNDER THE ACT OF AUGUST 1, 1956 § 12...

  5. 28 CFR 12.23 - Deficient registration statement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 1 2011-07-01 2011-07-01 false Deficient registration statement. 12.23 Section 12.23 Judicial Administration DEPARTMENT OF JUSTICE REGISTRATION OF CERTAIN PERSONS HAVING KNOWLEDGE OF FOREIGN ESPIONAGE, COUNTERESPIONAGE, OR SABOTAGE MATTERS UNDER THE ACT OF AUGUST 1, 1956 § 12...

  6. 28 CFR 10.2 - Language of registration statement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... statement. Registration statements must be in English if possible. If in a foreign language they must be accompanied by an English translation certified under oath by the translator, before a notary public or other...

  7. 28 CFR 12.20 - Filing of registration statement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Filing of registration statement. 12.20 Section 12.20 Judicial Administration DEPARTMENT OF JUSTICE REGISTRATION OF CERTAIN PERSONS HAVING KNOWLEDGE OF FOREIGN ESPIONAGE, COUNTERESPIONAGE, OR SABOTAGE MATTERS UNDER THE ACT OF AUGUST 1, 1956 § 12...

  8. 28 CFR 12.20 - Filing of registration statement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 1 2013-07-01 2013-07-01 false Filing of registration statement. 12.20 Section 12.20 Judicial Administration DEPARTMENT OF JUSTICE REGISTRATION OF CERTAIN PERSONS HAVING KNOWLEDGE OF FOREIGN ESPIONAGE, COUNTERESPIONAGE, OR SABOTAGE MATTERS UNDER THE ACT OF AUGUST 1, 1956 § 12...

  9. 28 CFR 12.20 - Filing of registration statement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 1 2012-07-01 2012-07-01 false Filing of registration statement. 12.20 Section 12.20 Judicial Administration DEPARTMENT OF JUSTICE REGISTRATION OF CERTAIN PERSONS HAVING KNOWLEDGE OF FOREIGN ESPIONAGE, COUNTERESPIONAGE, OR SABOTAGE MATTERS UNDER THE ACT OF AUGUST 1, 1956 § 12...

  10. 28 CFR 12.20 - Filing of registration statement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 1 2014-07-01 2014-07-01 false Filing of registration statement. 12.20 Section 12.20 Judicial Administration DEPARTMENT OF JUSTICE REGISTRATION OF CERTAIN PERSONS HAVING KNOWLEDGE OF FOREIGN ESPIONAGE, COUNTERESPIONAGE, OR SABOTAGE MATTERS UNDER THE ACT OF AUGUST 1, 1956 § 12...

  11. 28 CFR 12.20 - Filing of registration statement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 1 2011-07-01 2011-07-01 false Filing of registration statement. 12.20 Section 12.20 Judicial Administration DEPARTMENT OF JUSTICE REGISTRATION OF CERTAIN PERSONS HAVING KNOWLEDGE OF FOREIGN ESPIONAGE, COUNTERESPIONAGE, OR SABOTAGE MATTERS UNDER THE ACT OF AUGUST 1, 1956 § 12...

  12. 17 CFR 274.13 - Form N-8B-3, registration statement of unincorporated management investment companies currently...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... statement of unincorporated management investment companies currently issuing periodic payment plan...-8B-3, registration statement of unincorporated management investment companies currently issuing..., pursuant to section 8(b) of the Investment Company Act of 1940, by unincorporated management investment...

  13. 28 CFR 12.22 - Material contents of registration statement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... HAVING KNOWLEDGE OF FOREIGN ESPIONAGE, COUNTERESPIONAGE, OR SABOTAGE MATTERS UNDER THE ACT OF AUGUST 1... detailed statement setting forth the nature of the registrant's knowledge of the espionage... instruction or training received by the registrant in the espionage, counterespionage, or sabotage service or...

  14. 28 CFR 12.22 - Material contents of registration statement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... HAVING KNOWLEDGE OF FOREIGN ESPIONAGE, COUNTERESPIONAGE, OR SABOTAGE MATTERS UNDER THE ACT OF AUGUST 1... detailed statement setting forth the nature of the registrant's knowledge of the espionage... instruction or training received by the registrant in the espionage, counterespionage, or sabotage service or...

  15. 28 CFR 12.22 - Material contents of registration statement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... HAVING KNOWLEDGE OF FOREIGN ESPIONAGE, COUNTERESPIONAGE, OR SABOTAGE MATTERS UNDER THE ACT OF AUGUST 1... detailed statement setting forth the nature of the registrant's knowledge of the espionage... instruction or training received by the registrant in the espionage, counterespionage, or sabotage service or...

  16. 28 CFR 12.22 - Material contents of registration statement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... HAVING KNOWLEDGE OF FOREIGN ESPIONAGE, COUNTERESPIONAGE, OR SABOTAGE MATTERS UNDER THE ACT OF AUGUST 1... detailed statement setting forth the nature of the registrant's knowledge of the espionage... instruction or training received by the registrant in the espionage, counterespionage, or sabotage service or...

  17. 28 CFR 12.22 - Material contents of registration statement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... HAVING KNOWLEDGE OF FOREIGN ESPIONAGE, COUNTERESPIONAGE, OR SABOTAGE MATTERS UNDER THE ACT OF AUGUST 1... detailed statement setting forth the nature of the registrant's knowledge of the espionage... instruction or training received by the registrant in the espionage, counterespionage, or sabotage service or...

  18. 17 CFR 274.11a-1 - Form N-2, registration statement of closed end management investment companies.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... statement of closed end management investment companies. 274.11a-1 Section 274.11a-1 Commodity and... management investment companies. This form shall be used as the registration statement to be filed pursuant to section 8(b) of the Investment Company Act of 1940 by closed end management investment companies...

  19. 17 CFR 210.2-04 - Examination of financial statements of persons other than the registrant.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... SECURITIES AND EXCHANGE COMMISSION FORM AND CONTENT OF AND REQUIREMENTS FOR FINANCIAL STATEMENTS, SECURITIES... Qualifications and Reports of Accountants § 210.2-04 Examination of financial statements of persons other than the registrant. If a registrant is required to file financial statements of any other person, such...

  20. 17 CFR 230.486 - Effective date of post-effective amendments and registration statements filed by certain closed...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 2 2013-04-01 2013-04-01 false Effective date of post....486 Effective date of post-effective amendments and registration statements filed by certain closed... section, a post-effective amendment to a registration statement, or a registration statement filed for the...

  1. 17 CFR 230.486 - Effective date of post-effective amendments and registration statements filed by certain closed...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 2 2012-04-01 2012-04-01 false Effective date of post....486 Effective date of post-effective amendments and registration statements filed by certain closed... section, a post-effective amendment to a registration statement, or a registration statement filed for the...

  2. 17 CFR 230.486 - Effective date of post-effective amendments and registration statements filed by certain closed...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 3 2014-04-01 2014-04-01 false Effective date of post....486 Effective date of post-effective amendments and registration statements filed by certain closed... section, a post-effective amendment to a registration statement, or a registration statement filed for the...

  3. 17 CFR 230.486 - Effective date of post-effective amendments and registration statements filed by certain closed...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 2 2011-04-01 2011-04-01 false Effective date of post....486 Effective date of post-effective amendments and registration statements filed by certain closed... section, a post-effective amendment to a registration statement, or a registration statement filed for the...

  4. 28 CFR 5.200 - Registration.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... supplemental statement at intervals of 6 months for the duration of the principal-agent relationship requiring registration. (b) The initial statement shall be filed on a form provided by the Registration Unit. (28 U.S.C...

  5. 28 CFR 5.200 - Registration.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... supplemental statement at intervals of 6 months for the duration of the principal-agent relationship requiring registration. (b) The initial statement shall be filed on a form provided by the Registration Unit. (28 U.S.C...

  6. 28 CFR 5.200 - Registration.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... supplemental statement at intervals of 6 months for the duration of the principal-agent relationship requiring registration. (b) The initial statement shall be filed on a form provided by the Registration Unit. (28 U.S.C...

  7. 28 CFR 5.200 - Registration.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... supplemental statement at intervals of 6 months for the duration of the principal-agent relationship requiring registration. (b) The initial statement shall be filed on a form provided by the Registration Unit. (28 U.S.C...

  8. 28 CFR 5.200 - Registration.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... supplemental statement at intervals of 6 months for the duration of the principal-agent relationship requiring registration. (b) The initial statement shall be filed on a form provided by the Registration Unit. (28 U.S.C...

  9. 28 CFR 12.21 - Time within which registration statement must be filed.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 1 2011-07-01 2011-07-01 false Time within which registration statement must be filed. 12.21 Section 12.21 Judicial Administration DEPARTMENT OF JUSTICE REGISTRATION OF CERTAIN PERSONS HAVING KNOWLEDGE OF FOREIGN ESPIONAGE, COUNTERESPIONAGE, OR SABOTAGE MATTERS UNDER THE ACT...

  10. 28 CFR 12.21 - Time within which registration statement must be filed.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 1 2012-07-01 2012-07-01 false Time within which registration statement must be filed. 12.21 Section 12.21 Judicial Administration DEPARTMENT OF JUSTICE REGISTRATION OF CERTAIN PERSONS HAVING KNOWLEDGE OF FOREIGN ESPIONAGE, COUNTERESPIONAGE, OR SABOTAGE MATTERS UNDER THE ACT...

  11. 28 CFR 12.21 - Time within which registration statement must be filed.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 1 2014-07-01 2014-07-01 false Time within which registration statement must be filed. 12.21 Section 12.21 Judicial Administration DEPARTMENT OF JUSTICE REGISTRATION OF CERTAIN PERSONS HAVING KNOWLEDGE OF FOREIGN ESPIONAGE, COUNTERESPIONAGE, OR SABOTAGE MATTERS UNDER THE ACT...

  12. 28 CFR 12.21 - Time within which registration statement must be filed.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 1 2013-07-01 2013-07-01 false Time within which registration statement must be filed. 12.21 Section 12.21 Judicial Administration DEPARTMENT OF JUSTICE REGISTRATION OF CERTAIN PERSONS HAVING KNOWLEDGE OF FOREIGN ESPIONAGE, COUNTERESPIONAGE, OR SABOTAGE MATTERS UNDER THE ACT...

  13. 28 CFR 12.21 - Time within which registration statement must be filed.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Time within which registration statement must be filed. 12.21 Section 12.21 Judicial Administration DEPARTMENT OF JUSTICE REGISTRATION OF CERTAIN PERSONS HAVING KNOWLEDGE OF FOREIGN ESPIONAGE, COUNTERESPIONAGE, OR SABOTAGE MATTERS UNDER THE ACT...

  14. 17 CFR 274.11A - Form N-1A, registration statement of open-end management investment companies.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... statement of open-end management investment companies. 274.11A Section 274.11A Commodity and Securities...(b) of the Investment Company Act of 1940 by open-end management investment companies other than... registration under the Securities Act of 1933 of the securities of all open-end management investment companies...

  15. 17 CFR 274.10 - Form N-8A, for notification of registration.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Form N-8A, for notification of... (CONTINUED) FORMS PRESCRIBED UNDER THE INVESTMENT COMPANY ACT OF 1940 Registration Statements § 274.10 Form N...: For Federal Register citations affecting Form N-8A, see the List of CFR Sections Affected, which...

  16. 17 CFR 274.10 - Form N-8A, for notification of registration.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Form N-8A, for notification of... (CONTINUED) FORMS PRESCRIBED UNDER THE INVESTMENT COMPANY ACT OF 1940 Registration Statements § 274.10 Form N...: For Federal Register citations affecting Form N-8A, see the List of CFR Sections Affected, which...

  17. 17 CFR 230.484 - Undertaking required in certain registration statements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Undertaking required in certain registration statements. 230.484 Section 230.484 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION GENERAL RULES AND REGULATIONS, SECURITIES ACT OF 1933 Investment Companies; Business...

  18. 17 CFR 230.487 - Effectiveness of registration statements filed by certain unit investment trusts.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... time of effectiveness of a series of such trust. Any such suspension, so long as it is in effect, shall... offering of the securities of a series of the unit investment trust, except the first series of such trust, may designate a date and time for such registration statement to become effective. If the registrant...

  19. 17 CFR 230.487 - Effectiveness of registration statements filed by certain unit investment trusts.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... time of effectiveness of a series of such trust. Any such suspension, so long as it is in effect, shall... offering of the securities of a series of the unit investment trust, except the first series of such trust, may designate a date and time for such registration statement to become effective. If the registrant...

  20. 17 CFR 270.0-3 - Amendments to registration statements and reports.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Amendments to registration statements and reports. 270.0-3 Section 270.0-3 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) RULES AND REGULATIONS, INVESTMENT COMPANY ACT OF 1940 § 270.0-3 Amendments to...

  1. 17 CFR 230.428 - Documents constituting a section 10(a) prospectus for Form S-8 registration statement...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... employee benefit plan information required by Item 1 of the Form; (ii) The statement of availability of registrant information, employee benefit plan annual reports and other information required by Item 2; and (iii) The documents containing registrant information and employee benefit plan annual reports that are...

  2. 17 CFR 230.488 - Effective date of registration statements relating to securities to be issued in certain business...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... statements relating to securities to be issued in certain business combination transactions. 230.488 Section... REGULATIONS, SECURITIES ACT OF 1933 Investment Companies; Business Development Companies § 230.488 Effective date of registration statements relating to securities to be issued in certain business combination...

  3. 28 CFR 5.203 - Supplemental statement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... on a form provided by the Registration Unit. (b) The obligation to file a supplemental statement at 6-month intervals during the agency relationship shall continue even though the registrant has not engaged...

  4. 28 CFR 5.203 - Supplemental statement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... on a form provided by the Registration Unit. (b) The obligation to file a supplemental statement at 6-month intervals during the agency relationship shall continue even though the registrant has not engaged...

  5. 28 CFR 5.203 - Supplemental statement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... on a form provided by the Registration Unit. (b) The obligation to file a supplemental statement at 6-month intervals during the agency relationship shall continue even though the registrant has not engaged...

  6. 28 CFR 5.203 - Supplemental statement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... on a form provided by the Registration Unit. (b) The obligation to file a supplemental statement at 6-month intervals during the agency relationship shall continue even though the registrant has not engaged...

  7. 28 CFR 5.203 - Supplemental statement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... on a form provided by the Registration Unit. (b) The obligation to file a supplemental statement at 6-month intervals during the agency relationship shall continue even though the registrant has not engaged...

  8. Lesson 6: Registration

    EPA Pesticide Factsheets

    Lesson 6 provides CROMERR checklist items grouped under the Registration Process, where users establish their accounts in the system. This process typically requires users to provide information about them.

  9. 21 CFR 710.6 - Notification of registrant; cosmetic product establishment registration number.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 7 2013-04-01 2013-04-01 false Notification of registrant; cosmetic product... OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS VOLUNTARY REGISTRATION OF COSMETIC PRODUCT ESTABLISHMENTS § 710.6 Notification of registrant; cosmetic product establishment registration number. The...

  10. 21 CFR 710.6 - Notification of registrant; cosmetic product establishment registration number.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 7 2012-04-01 2012-04-01 false Notification of registrant; cosmetic product... OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS VOLUNTARY REGISTRATION OF COSMETIC PRODUCT ESTABLISHMENTS § 710.6 Notification of registrant; cosmetic product establishment registration number. The...

  11. 21 CFR 710.6 - Notification of registrant; cosmetic product establishment registration number.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Notification of registrant; cosmetic product... OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS VOLUNTARY REGISTRATION OF COSMETIC PRODUCT ESTABLISHMENTS § 710.6 Notification of registrant; cosmetic product establishment registration number. The...

  12. 21 CFR 710.6 - Notification of registrant; cosmetic product establishment registration number.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 7 2011-04-01 2010-04-01 true Notification of registrant; cosmetic product... OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS VOLUNTARY REGISTRATION OF COSMETIC PRODUCT ESTABLISHMENTS § 710.6 Notification of registrant; cosmetic product establishment registration number. The...

  13. 21 CFR 710.6 - Notification of registrant; cosmetic product establishment registration number.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 7 2014-04-01 2014-04-01 false Notification of registrant; cosmetic product... OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS VOLUNTARY REGISTRATION OF COSMETIC PRODUCT ESTABLISHMENTS § 710.6 Notification of registrant; cosmetic product establishment registration number. The...

  14. 17 CFR 230.430A - Prospectus in a registration statement at the time of effectiveness.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... SECURITIES AND EXCHANGE COMMISSION GENERAL RULES AND REGULATIONS, SECURITIES ACT OF 1933 Form and Content of Prospectuses § 230.430A Prospectus in a registration statement at the time of effectiveness. (a) The form of... respect to the public offering price, underwriting syndicate (including any material relationships between...

  15. 17 CFR 230.486 - Effective date of post-effective amendments and registration statements filed by certain closed...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...-effective amendments and registration statements filed by certain closed-end management investment companies...-end management investment companies. (a) Automatic effectiveness. Except as otherwise provided in this... management investment company or business development company which makes periodic repurchase offers under...

  16. 49 CFR 1112.6 - Verified statements; contents.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 8 2012-10-01 2012-10-01 false Verified statements; contents. 1112.6 Section 1112.6 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION RULES OF PRACTICE MODIFIED PROCEDURES § 1112.6 Verified statements; contents. A verified statement should contain...

  17. 49 CFR 1112.6 - Verified statements; contents.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 8 2013-10-01 2013-10-01 false Verified statements; contents. 1112.6 Section 1112.6 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION RULES OF PRACTICE MODIFIED PROCEDURES § 1112.6 Verified statements; contents. A verified statement should contain...

  18. 17 CFR 49.6 - Registration of successor entities.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 1 2012-04-01 2012-04-01 false Registration of successor entities. 49.6 Section 49.6 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION SWAP DATA REPOSITORIES § 49.6 Registration of successor entities. (a) In the event of a corporate...

  19. 17 CFR 49.6 - Registration of successor entities.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 1 2013-04-01 2013-04-01 false Registration of successor entities. 49.6 Section 49.6 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION SWAP DATA REPOSITORIES § 49.6 Registration of successor entities. (a) In the event of a corporate...

  20. 17 CFR 49.6 - Registration of successor entities.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 2 2014-04-01 2014-04-01 false Registration of successor entities. 49.6 Section 49.6 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION (CONTINUED) SWAP DATA REPOSITORIES § 49.6 Registration of successor entities. (a) In the event of a corporate...

  1. 14 CFR 313.6 - Energy statements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 4 2013-01-01 2013-01-01 false Energy statements. 313.6 Section 313.6... REGULATIONS IMPLEMENTATION OF THE ENERGY POLICY AND CONSERVATION ACT § 313.6 Energy statements. (a) Each major... action taken or to be taken upon energy efficiency and conservation. The administrative law judge or the...

  2. 14 CFR 313.6 - Energy statements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 4 2012-01-01 2012-01-01 false Energy statements. 313.6 Section 313.6... REGULATIONS IMPLEMENTATION OF THE ENERGY POLICY AND CONSERVATION ACT § 313.6 Energy statements. (a) Each major... action taken or to be taken upon energy efficiency and conservation. The administrative law judge or the...

  3. 14 CFR 313.6 - Energy statements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false Energy statements. 313.6 Section 313.6... REGULATIONS IMPLEMENTATION OF THE ENERGY POLICY AND CONSERVATION ACT § 313.6 Energy statements. (a) Each major... action taken or to be taken upon energy efficiency and conservation. The administrative law judge or the...

  4. 14 CFR 313.6 - Energy statements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 4 2014-01-01 2014-01-01 false Energy statements. 313.6 Section 313.6... REGULATIONS IMPLEMENTATION OF THE ENERGY POLICY AND CONSERVATION ACT § 313.6 Energy statements. (a) Each major... action taken or to be taken upon energy efficiency and conservation. The administrative law judge or the...

  5. 14 CFR 313.6 - Energy statements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Energy statements. 313.6 Section 313.6... REGULATIONS IMPLEMENTATION OF THE ENERGY POLICY AND CONSERVATION ACT § 313.6 Energy statements. (a) Each major... action taken or to be taken upon energy efficiency and conservation. The administrative law judge or the...

  6. 32 CFR 1648.6 - Registrants transferred for classification.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 6 2014-07-01 2014-07-01 false Registrants transferred for classification. 1648... SYSTEM CLASSIFICATION BY LOCAL BOARD § 1648.6 Registrants transferred for classification. (a) Before a..., be transferred for classification to a local board nearer to his current address than is the local...

  7. 32 CFR 1648.6 - Registrants transferred for classification.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 6 2013-07-01 2013-07-01 false Registrants transferred for classification. 1648... SYSTEM CLASSIFICATION BY LOCAL BOARD § 1648.6 Registrants transferred for classification. (a) Before a..., be transferred for classification to a local board nearer to his current address than is the local...

  8. 32 CFR 1648.6 - Registrants transferred for classification.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Registrants transferred for classification. 1648... SYSTEM CLASSIFICATION BY LOCAL BOARD § 1648.6 Registrants transferred for classification. (a) Before a..., be transferred for classification to a local board nearer to his current address than is the local...

  9. 32 CFR 1648.6 - Registrants transferred for classification.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 6 2011-07-01 2011-07-01 false Registrants transferred for classification. 1648... SYSTEM CLASSIFICATION BY LOCAL BOARD § 1648.6 Registrants transferred for classification. (a) Before a..., be transferred for classification to a local board nearer to his current address than is the local...

  10. 32 CFR 1648.6 - Registrants transferred for classification.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 6 2012-07-01 2012-07-01 false Registrants transferred for classification. 1648... SYSTEM CLASSIFICATION BY LOCAL BOARD § 1648.6 Registrants transferred for classification. (a) Before a..., be transferred for classification to a local board nearer to his current address than is the local...

  11. 40 CFR 6.207 - Environmental impact statements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Environmental impact statements. 6.207 Section 6.207 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL PROCEDURES FOR... ACTIONS EPA's NEPA Environmental Review Procedures § 6.207 Environmental impact statements. (a) The...

  12. 40 CFR 6.207 - Environmental impact statements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Environmental impact statements. 6.207 Section 6.207 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL PROCEDURES FOR... ACTIONS EPA's NEPA Environmental Review Procedures § 6.207 Environmental impact statements. (a) The...

  13. 17 CFR 229.501 - (Item 501) Forepart of Registration Statement and Outside Front Cover Page of Prospectus.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... you use § 230.430A of this chapter to omit pricing information and the prospectus is used before you... Statement and Outside Front Cover Page of Prospectus. The registrant must furnish the following information... page. If the following information applies to your offering, disclose it on the outside cover page of...

  14. 21 CFR 201.6 - Drugs; misleading statements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 4 2011-04-01 2011-04-01 false Drugs; misleading statements. 201.6 Section 201.6 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL LABELING General Labeling Provisions § 201.6 Drugs; misleading statements. (a) Among...

  15. 21 CFR 201.6 - Drugs; misleading statements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 4 2014-04-01 2014-04-01 false Drugs; misleading statements. 201.6 Section 201.6 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL LABELING General Labeling Provisions § 201.6 Drugs; misleading statements. (a) Among...

  16. 21 CFR 201.6 - Drugs; misleading statements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 4 2012-04-01 2012-04-01 false Drugs; misleading statements. 201.6 Section 201.6 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL LABELING General Labeling Provisions § 201.6 Drugs; misleading statements. (a) Among...

  17. 21 CFR 201.6 - Drugs; misleading statements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 4 2013-04-01 2013-04-01 false Drugs; misleading statements. 201.6 Section 201.6 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL LABELING General Labeling Provisions § 201.6 Drugs; misleading statements. (a) Among...

  18. 17 CFR 240.6a-1 - Application for registration as a national securities exchange or exemption from registration...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... as a national securities exchange or exemption from registration based on limited volume. 240.6a-1... national securities exchange or exemption from registration based on limited volume. (a) An application for registration as a national securities exchange, or for exemption from such registration based on limited volume...

  19. 17 CFR 240.6a-1 - Application for registration as a national securities exchange or exemption from registration...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... as a national securities exchange or exemption from registration based on limited volume. 240.6a-1... national securities exchange or exemption from registration based on limited volume. (a) An application for registration as a national securities exchange, or for exemption from such registration based on limited volume...

  20. 48 CFR 222.406-6 - Payrolls and statements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Payrolls and statements... Labor Standards for Contracts Involving Construction 222.406-6 Payrolls and statements. (a) Submission..., Statement of Compliance, with each payroll report. ...

  1. 12 CFR 230.6 - Periodic statement disclosures.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... SYSTEM TRUTH IN SAVINGS (REGULATION DD) § 230.6 Periodic statement disclosures. (a) General rule. If a... be stated for that period as well as for the statement period. [Reg. DD 57 FR 43376, Sept. 21, 1992...

  2. 48 CFR 52.247-6 - Financial Statement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ....247-6 Financial Statement. As prescribed in 47.207-1(e), insert the following provision in solicitations for transportation or for transportation-related services to ensure that offerors are prepared to... furnish the Government with a current certified statement of the offeror's financial condition and such...

  3. 48 CFR 52.247-6 - Financial Statement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ....247-6 Financial Statement. As prescribed in 47.207-1(e), insert the following provision in solicitations for transportation or for transportation-related services to ensure that offerors are prepared to... furnish the Government with a current certified statement of the offeror's financial condition and such...

  4. 21 CFR 720.6 - Amendments to statement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS VOLUNTARY FILING OF COSMETIC PRODUCT INGREDIENT COMPOSITION STATEMENTS § 720.6 Amendments to statement... a cosmetic product should be submitted by filing an amended Form FDA 2512 within 60 days after the...

  5. 21 CFR 720.6 - Amendments to statement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS VOLUNTARY FILING OF COSMETIC PRODUCT INGREDIENT COMPOSITION STATEMENTS § 720.6 Amendments to statement... a cosmetic product should be submitted by filing an amended Form FDA 2512 within 60 days after the...

  6. 21 CFR 720.6 - Amendments to statement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS VOLUNTARY FILING OF COSMETIC PRODUCT INGREDIENT COMPOSITION STATEMENTS § 720.6 Amendments to statement... a cosmetic product should be submitted by filing an amended Form FDA 2512 within 60 days after the...

  7. 21 CFR 720.6 - Amendments to statement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS VOLUNTARY FILING OF COSMETIC PRODUCT INGREDIENT COMPOSITION STATEMENTS § 720.6 Amendments to statement... a cosmetic product should be submitted by filing an amended Form FDA 2512 within 60 days after the...

  8. 21 CFR 720.6 - Amendments to statement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS VOLUNTARY FILING OF COSMETIC PRODUCT INGREDIENT COMPOSITION STATEMENTS § 720.6 Amendments to statement... a cosmetic product should be submitted by filing an amended Form FDA 2512 within 60 days after the...

  9. 17 CFR 270.8b-16 - Amendments to registration statement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... on Form N-SAR, as prescribed by rule 30b1-1 (17 CFR 270.30b1-1), shall amend the registration... information is transmitted to shareholders in its annual report to shareholders: (1) If the company offers a dividend reinvestment plan to shareholders, information about the plan required to be disclosed in the...

  10. 17 CFR 270.8b-16 - Amendments to registration statement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... on Form N-SAR, as prescribed by rule 30b1-1 (17 CFR 270.30b1-1), shall amend the registration... information is transmitted to shareholders in its annual report to shareholders: (1) If the company offers a dividend reinvestment plan to shareholders, information about the plan required to be disclosed in the...

  11. 17 CFR 270.8b-16 - Amendments to registration statement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... on Form N-SAR, as prescribed by rule 30b1-1 (17 CFR 270.30b1-1), shall amend the registration... information is transmitted to shareholders in its annual report to shareholders: (1) If the company offers a dividend reinvestment plan to shareholders, information about the plan required to be disclosed in the...

  12. 17 CFR 270.8b-16 - Amendments to registration statement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... on Form N-SAR, as prescribed by rule 30b1-1 (17 CFR 270.30b1-1), shall amend the registration... information is transmitted to shareholders in its annual report to shareholders: (1) If the company offers a dividend reinvestment plan to shareholders, information about the plan required to be disclosed in the...

  13. 28 CFR 5.205 - Termination of registration.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... supplemental statement form with the Registration Unit for the final period of the agency relationship not... of the agency relationship with the foreign principals. (d) Registration under the Act may be terminated upon a finding that the registrant is unable to file the appropriate forms to terminate the...

  14. 28 CFR 5.205 - Termination of registration.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... supplemental statement form with the Registration Unit for the final period of the agency relationship not... of the agency relationship with the foreign principals. (d) Registration under the Act may be terminated upon a finding that the registrant is unable to file the appropriate forms to terminate the...

  15. 28 CFR 5.205 - Termination of registration.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... supplemental statement form with the Registration Unit for the final period of the agency relationship not... of the agency relationship with the foreign principals. (d) Registration under the Act may be terminated upon a finding that the registrant is unable to file the appropriate forms to terminate the...

  16. 28 CFR 5.205 - Termination of registration.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... supplemental statement form with the Registration Unit for the final period of the agency relationship not... of the agency relationship with the foreign principals. (d) Registration under the Act may be terminated upon a finding that the registrant is unable to file the appropriate forms to terminate the...

  17. 28 CFR 5.205 - Termination of registration.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... supplemental statement form with the Registration Unit for the final period of the agency relationship not... of the agency relationship with the foreign principals. (d) Registration under the Act may be terminated upon a finding that the registrant is unable to file the appropriate forms to terminate the...

  18. 27 CFR 19.123 - Statement of plant security.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Statement of plant... BUREAU, DEPARTMENT OF THE TREASURY LIQUORS DISTILLED SPIRITS PLANTS Changes to Registrations and Permits Rules for Amending A Registration § 19.123 Statement of plant security. If the proprietor makes changes...

  19. 27 CFR 19.123 - Statement of plant security.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2013-04-01 2013-04-01 false Statement of plant... BUREAU, DEPARTMENT OF THE TREASURY ALCOHOL DISTILLED SPIRITS PLANTS Changes to Registrations and Permits Rules for Amending A Registration § 19.123 Statement of plant security. If the proprietor makes changes...

  20. 40 CFR 152.135 - Transfer of registration.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., spinoff, bankruptcy transfer (no financial information need be disclosed); (7) A statement that the transferor and transferee understand that any false statement may be punishable under 18 U.S.C. 1001; and (8...) The name(s) and EPA registration number(s) of the product(s) being transferred; (4) A statement that...

  1. 17 CFR 210.6-05 - Statements of net assets.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Statements of net assets. In lieu of the balance sheet otherwise required by § 210.6-04 of this part, persons... noncontrolled affiliates which arose in the ordinary course of business and which are subject to usual trade... statements for any item required under §§ 210.6-04.10 to 210.6-04.13. 4. The balance of the amounts captioned...

  2. 17 CFR 210.6-05 - Statements of net assets.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Statements of net assets. In lieu of the balance sheet otherwise required by § 210.6-04 of this part, persons... noncontrolled affiliates which arose in the ordinary course of business and which are subject to usual trade... statements for any item required under §§ 210.6-04.10 to 210.6-04.13. 4. The balance of the amounts captioned...

  3. 17 CFR 31.6 - Registration of leverage commodities.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... commodities. 31.6 Section 31.6 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION... applied to the National Futures Association for registration as a leverage transaction merchant; (2... the spot, forward, and futures markets for the generic commodity; (3) Specify a commercial or retail...

  4. 31 CFR 360.6 - Authorized forms of registration.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance:Treasury 2 2013-07-01 2013-07-01 false Authorized forms of registration. 360.6 Section 360.6 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued... Pension Fund of Safety Manufacturing Company, U/A with the company, dated March 31, 1996, 12-3456789...

  5. 31 CFR 360.6 - Authorized forms of registration.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance:Treasury 2 2011-07-01 2011-07-01 false Authorized forms of registration. 360.6 Section 360.6 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued... Pension Fund of Safety Manufacturing Company, U/A with the company, dated March 31, 1996, 12-3456789...

  6. 31 CFR 360.6 - Authorized forms of registration.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 31 Money and Finance:Treasury 2 2012-07-01 2012-07-01 false Authorized forms of registration. 360.6 Section 360.6 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued... Pension Fund of Safety Manufacturing Company, U/A with the company, dated March 31, 1996, 12-3456789...

  7. 31 CFR 360.6 - Authorized forms of registration.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance: Treasury 2 2014-07-01 2014-07-01 false Authorized forms of registration. 360.6 Section 360.6 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued... Pension Fund of Safety Manufacturing Company, U/A with the company, dated March 31, 1996, 12-3456789...

  8. 48 CFR 22.406-6 - Payrolls and statements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Payrolls and statements... Involving Construction 22.406-6 Payrolls and statements. (a) Submission. In accordance with the clause at 52.222-8, Payrolls and Basic Records, the contractor must submit or cause to be submitted, within 7...

  9. 12 CFR 500.6 - General statement concerning gender-related terminology.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 6 2013-01-01 2012-01-01 true General statement concerning gender-related... Supervision § 500.6 General statement concerning gender-related terminology. The statutes administered by the... inadvertently use or contain gender-related terminology are to be interpreted as equally applicable to either...

  10. 12 CFR 500.6 - General statement concerning gender-related terminology.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 6 2012-01-01 2012-01-01 false General statement concerning gender-related... Supervision § 500.6 General statement concerning gender-related terminology. The statutes administered by the... inadvertently use or contain gender-related terminology are to be interpreted as equally applicable to either...

  11. 12 CFR 500.6 - General statement concerning gender-related terminology.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 6 2014-01-01 2012-01-01 true General statement concerning gender-related... Supervision § 500.6 General statement concerning gender-related terminology. The statutes administered by the... inadvertently use or contain gender-related terminology are to be interpreted as equally applicable to either...

  12. 37 CFR 11.6 - Registration of attorneys and agents.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Registration of attorneys and agents. 11.6 Section 11.6 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE REPRESENTATION OF OTHERS BEFORE THE UNITED STATES PATENT AND TRADEMARK OFFICE...

  13. 28 CFR 5.206 - Language and wording of registration statement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 1 2011-07-01 2011-07-01 false Language and wording of registration... OF FOREIGN AGENTS REGISTRATION ACT OF 1938, AS AMENDED § 5.206 Language and wording of registration... required to be filed under the Act shall be submitted in the English language. An exhibit may be filed even...

  14. 7 CFR 1230.627 - Registration form and ballot.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... registration form includes name, address, and telephone number. Form LS-72-2 also contains the certification... required on this combined registration and voting form includes name, address, and telephone number. Form... includes name, address, and telephone number. Form LS-76 also contains the certification statement...

  15. 21 CFR 801.6 - Medical devices; misleading statements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Medical devices; misleading statements. 801.6 Section 801.6 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES LABELING General Labeling Provisions § 801.6 Medical devices; misleading...

  16. 21 CFR 801.6 - Medical devices; misleading statements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Medical devices; misleading statements. 801.6 Section 801.6 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES LABELING General Labeling Provisions § 801.6 Medical devices; misleading...

  17. 21 CFR 201.6 - Drugs; misleading statements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... representation with respect to another drug or a device or a food or cosmetic. (b) The labeling of a drug which... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Drugs; misleading statements. 201.6 Section 201.6 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS...

  18. 48 CFR 522.406-6 - Payrolls and statements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Payrolls and statements. 522.406-6 Section 522.406-6 Federal Acquisition Regulations System GENERAL SERVICES ADMINISTRATION SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Labor Standards for Contracts...

  19. Beating-heart registration for organ-mounted robots.

    PubMed

    Wood, Nathan A; Schwartzman, David; Passineau, Michael J; Moraca, Robert J; Zenati, Marco A; Riviere, Cameron N

    2018-03-06

    Organ-mounted robots address the problem of beating-heart surgery by adhering to the heart, passively providing a platform that approaches zero relative motion. Because of the quasi-periodic deformation of the heart due to heartbeat and respiration, registration must address not only spatial registration but also temporal registration. Motion data were collected in the porcine model in vivo (N = 6). Fourier series models of heart motion were developed. By comparing registrations generated using an iterative closest-point approach at different phases of respiration, the phase corresponding to minimum registration distance is identified. The spatiotemporal registration technique presented here reduces registration error by an average of 4.2 mm over the 6 trials, in comparison with a more simplistic static registration that merely averages out the physiological motion. An empirical metric for spatiotemporal registration of organ-mounted robots is defined and demonstrated using data from animal models in vivo. Copyright © 2018 John Wiley & Sons, Ltd.

  20. 12 CFR 500.6 - General statement concerning gender-related terminology.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false General statement concerning gender-related... Supervision § 500.6 General statement concerning gender-related terminology. The statutes administered by the... inadvertently use or contain gender-related terminology are to be interpreted as equally applicable to either...

  1. 12 CFR 500.6 - General statement concerning gender-related terminology.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 5 2011-01-01 2011-01-01 false General statement concerning gender-related... Supervision § 500.6 General statement concerning gender-related terminology. The statutes administered by the... inadvertently use or contain gender-related terminology are to be interpreted as equally applicable to either...

  2. Registration and Marking Requirements for UAS. Unmanned Aircraft System (UAS) Registration

    NASA Technical Reports Server (NTRS)

    2005-01-01

    The registration of an aircraft is a prerequisite for issuance of a U.S. certificate of airworthiness by the FAA. The procedures and requirements for aircraft registration, and the subsequent issuance of registration numbers, are contained in FAR Part 47. However, the process/method(s) for applying the requirements of Parts 45 & 47 to Unmanned Aircraft Systems (UAS) has not been defined. This task resolved the application of 14 CFR Parts 45 and 47 to UAS. Key Findings: UAS are aircraft systems and as such the recommended approach to registration is to follow the same process for registration as manned aircraft. This will require manufacturers to comply with the requirements for 14 CFR 47, Aircraft Registration and 14 CFR 45, Identification and Registration Marking. In addition, only the UA should be identified with the N number registration markings. There should also be a documentation link showing the applicability of the control station and communication link to the UA. The documentation link can be in the form of a Type Certificate Data Sheet (TCDS) entry or a UAS logbook entry. The recommended process for the registration of UAS is similar to the manned aircraft process and is outlined in a 6-step process in the paper.

  3. 49 CFR 385.306 - What are the consequences of furnishing misleading information or making a false statement in...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... information or making a false statement in connection with the registration process? 385.306 Section 385.306... information or making a false statement in connection with the registration process? A carrier that furnishes false or misleading information, or conceals material information in connection with the registration...

  4. 32 CFR 1642.8 - Statement of reason for denial.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... in turn, be supported by evidence in the registrant's file. (b) If a board's denial is based on statements by the registrant or his witnesses at a personal appearance, this must be fully explained in the...

  5. 48 CFR 9903.202-6 - Adequacy of Disclosure Statement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... COST ACCOUNTING STANDARDS CONTRACT COVERAGE CAS Program Requirements 9903.202-6 Adequacy of Disclosure... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Adequacy of Disclosure Statement. 9903.202-6 Section 9903.202-6 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS...

  6. 37 CFR 382.6 - Verification of statements of account.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... account. 382.6 Section 382.6 Patents, Trademarks, and Copyrights COPYRIGHT ROYALTY BOARD, LIBRARY OF CONGRESS RATES AND TERMS FOR STATUTORY LICENSES RATES AND TERMS FOR DIGITAL TRANSMISSIONS OF SOUND... SATELLITE DIGITAL AUDIO RADIO SERVICES Preexisting Subscription Services § 382.6 Verification of statements...

  7. 37 CFR 382.6 - Verification of statements of account.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... account. 382.6 Section 382.6 Patents, Trademarks, and Copyrights COPYRIGHT ROYALTY BOARD, LIBRARY OF CONGRESS RATES AND TERMS FOR STATUTORY LICENSES RATES AND TERMS FOR DIGITAL TRANSMISSIONS OF SOUND... SATELLITE DIGITAL AUDIO RADIO SERVICES Preexisting Subscription Services § 382.6 Verification of statements...

  8. 32 CFR 1639.8 - Statement of reason for denial.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) must in turn, be supported by evidence in the registrant's file. (b) If a board's denial is based on statements by the registrant or his witnesses at a personal appearance, this must be fully explained in the...

  9. 17 CFR 274.11 - Form N-1, registration statement of open-end management investment companies.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... statement of open-end management investment companies. 274.11 Section 274.11 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) FORMS PRESCRIBED UNDER THE INVESTMENT COMPANY ACT...(b) of the Investment Company Act of 1940 by open-end management investment companies that are...

  10. 43 CFR 1601.0-6 - Environmental impact statement policy.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false Environmental impact statement policy. 1601.0-6 Section 1601.0-6 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR GENERAL MANAGEMENT (1000) PLANNING, PROGRAMMING...

  11. 43 CFR 1601.0-6 - Environmental impact statement policy.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false Environmental impact statement policy. 1601.0-6 Section 1601.0-6 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR GENERAL MANAGEMENT (1000) PLANNING, PROGRAMMING...

  12. 43 CFR 1601.0-6 - Environmental impact statement policy.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false Environmental impact statement policy. 1601.0-6 Section 1601.0-6 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR GENERAL MANAGEMENT (1000) PLANNING, PROGRAMMING...

  13. 43 CFR 1601.0-6 - Environmental impact statement policy.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 2 2011-10-01 2011-10-01 false Environmental impact statement policy. 1601.0-6 Section 1601.0-6 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR GENERAL MANAGEMENT (1000) PLANNING, PROGRAMMING...

  14. 27 CFR 19.76 - Statement of plant security.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Statement of plant... BUREAU, DEPARTMENT OF THE TREASURY LIQUORS DISTILLED SPIRITS PLANTS Registration of a Distilled Spirits Plant and Obtaining a Permit Requirements for Registering A Plant § 19.76 Statement of plant security...

  15. 27 CFR 19.76 - Statement of plant security.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2013-04-01 2013-04-01 false Statement of plant... BUREAU, DEPARTMENT OF THE TREASURY ALCOHOL DISTILLED SPIRITS PLANTS Registration of a Distilled Spirits Plant and Obtaining a Permit Requirements for Registering A Plant § 19.76 Statement of plant security...

  16. 17 CFR 239.14 - Form N-2 for closed end management investment companies registered on Form N-8A.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... management investment companies registered on Form N-8A. 239.14 Section 239.14 Commodity and Securities... Registration Statements § 239.14 Form N-2 for closed end management investment companies registered on Form N... closed end management investment companies registered under the Investment Company Act of 1940 on form N...

  17. Verification and Validation of Monte Carlo n-Particle Code 6 (MCNP6) with Neutron Protection Factor Measurements of an Iron Box

    DTIC Science & Technology

    2014-03-27

    VERIFICATION AND VALIDATION OF MONTE CARLO N- PARTICLE CODE 6 (MCNP6) WITH NEUTRON PROTECTION FACTOR... PARTICLE CODE 6 (MCNP6) WITH NEUTRON PROTECTION FACTOR MEASUREMENTS OF AN IRON BOX THESIS Presented to the Faculty Department of Engineering...STATEMENT A. APPROVED FOR PUBLIC RELEASE; DISTRIBUTION UNLIMITED iv AFIT-ENP-14-M-05 VERIFICATION AND VALIDATION OF MONTE CARLO N- PARTICLE CODE 6

  18. 78 FR 16006 - Self-Regulatory Organizations; the NASDAQ Stock Market LLC; Notice of Filing of Proposed Rule...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-13

    ... registration statement on Form N-1A (``Registration Statement'') with the Commission.\\6\\ The Fund is a series... designed to prevent the use and dissemination of material, non-public information regarding the open-end... concerning the composition and/or changes to the portfolio and will be subject to procedures designed to...

  19. 6 CFR 13.22 - Exchange of witness lists, Statements, and exhibits.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 6 Domestic Security 1 2010-01-01 2010-01-01 false Exchange of witness lists, Statements, and exhibits. 13.22 Section 13.22 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY PROGRAM FRAUD CIVIL REMEDIES § 13.22 Exchange of witness lists, Statements, and exhibits. (a) At least 15...

  20. 22 CFR 50.6 - Registration at the Department of birth abroad.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Registration at the Department of birth abroad. 50.6 Section 50.6 Foreign Relations DEPARTMENT OF STATE NATIONALITY AND PASSPORTS NATIONALITY... at the Department of birth abroad. In the time of war or national emergency, passport agents may be...

  1. 22 CFR 50.6 - Registration at the Department of birth abroad.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Registration at the Department of birth abroad. 50.6 Section 50.6 Foreign Relations DEPARTMENT OF STATE NATIONALITY AND PASSPORTS NATIONALITY... at the Department of birth abroad. In the time of war or national emergency, passport agents may be...

  2. 22 CFR 50.6 - Registration at the Department of birth abroad.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Registration at the Department of birth abroad. 50.6 Section 50.6 Foreign Relations DEPARTMENT OF STATE NATIONALITY AND PASSPORTS NATIONALITY... at the Department of birth abroad. In the time of war or national emergency, passport agents may be...

  3. 22 CFR 50.6 - Registration at the Department of birth abroad.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Registration at the Department of birth abroad. 50.6 Section 50.6 Foreign Relations DEPARTMENT OF STATE NATIONALITY AND PASSPORTS NATIONALITY... at the Department of birth abroad. In the time of war or national emergency, passport agents may be...

  4. 22 CFR 50.6 - Registration at the Department of birth abroad.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Registration at the Department of birth abroad. 50.6 Section 50.6 Foreign Relations DEPARTMENT OF STATE NATIONALITY AND PASSPORTS NATIONALITY... at the Department of birth abroad. In the time of war or national emergency, passport agents may be...

  5. Endorsement of the CONSORT guidelines, trial registration, and the quality of reporting randomised controlled trials in leading nursing journals: A cross-sectional analysis.

    PubMed

    Jull, Andrew; Aye, Phyu Sin

    2015-06-01

    To establish the reporting quality of trials published in leading nursing journals and investigate associations between CONSORT Statement or trial registration endorsment and reporting of design elements. The top 15 nursing journals were searched using Medline for randomised controlled trials published in 2012. Journals were categorised as CONSORT and trial registration promoting based on requirements of submitting authors or the journal's webpage as at January 2014. Data on sequence generation, allocation concealment, follow up, blinding, baseline equivalence and sample size calculation were extracted by one author and independently verified by the second author against source data. Seven journals were CONSORT promoting and three of these journals were also trial registration promoting. 114 citations were identified and 83 were randomised controlled trials. Eighteen trials (21.7%) were registered and those published in trial registration promoting journals were more likely to be registered (RR 2.64 95%CI 1.14-6.09). We assessed 68.7% of trials to be low risk of bias for sequence generation, 20.5% for allocation concealment, 38.6% for blinding, 55.4% for completeness of follow up and 79.5% for baseline equivalence. Trials published in CONSORT promoting journals were more likely to be at low risk of bias for blinding (RR 2.33, 95%CI 1.01-5.34) and completeness of follow up (RR 1.77, 95%CI 1.02-3.10), but journal endorsement of the CONSORT Statement or trial registration otherwise had no significant effect. Trials published in CONSORT and trial registration promoting journals were more likely to have high quality sample size calculations (RR 2.91, 95%CI 1.18-7.19 and RR 1.69, 95%CI 1.08-2.64, respectively). Simple endorsement of the CONSORT Statement and trials registration is insufficient action to encourage improvement of the quality of trial reporting across the most important of trial design elements. Copyright © 2014 Elsevier Ltd. All rights reserved.

  6. 17 CFR 239.15 - Form N-1 for open-end management investment companies registered on Form N-8A.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... management investment companies registered on Form N-8A. 239.15 Section 239.15 Commodity and Securities... Registration Statements § 239.15 Form N-1 for open-end management investment companies registered on Form N-8A...-end management investment companies that are separate accounts of insurance companies as defined by...

  7. PRN 83-3: Label Improvement Program - Storage and Disposal Label Statements

    EPA Pesticide Factsheets

    This Notice is to inform all registrants that the label of all pesticide products must include updated storage and disposal statements. No application for amended registration is required if you use the exact wording contained in this Notice.

  8. 17 CFR 210.6A-04 - Statements of income and changes in plan equity.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Statements of income and..., Savings and Similar Plans § 210.6A-04 Statements of income and changes in plan equity. Statements of income and changes in plan equity filed under this rule shall comply with the following provisions: 1...

  9. 17 CFR 210.6A-04 - Statements of income and changes in plan equity.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 2 2011-04-01 2011-04-01 false Statements of income and..., Savings and Similar Plans § 210.6A-04 Statements of income and changes in plan equity. Statements of income and changes in plan equity filed under this rule shall comply with the following provisions: 1...

  10. 77 FR 37605 - Registration of Claims to Copyright

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-22

    ... in selection and arrangement of exercises or of other uncopyrightable matter. The statement also... practices with respect to claims in ``compilation authorship,'' or the selection, coordination, or... registration based on the selection, coordination, or arrangement of uncopyrightable elements, because the...

  11. 17 CFR 210.6-08 - Special provisions applicable to the statements of operations of issuers of face-amount...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... to the statements of operations of issuers of face-amount certificates. 210.6-08 Section 210.6-08... applicable to the statements of operations of issuers of face-amount certificates. Statements of operations filed by issuers of face-amount certificates shall comply with the following provisions: Statements of...

  12. 17 CFR 210.6-08 - Special provisions applicable to the statements of operations of issuers of face-amount...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... to the statements of operations of issuers of face-amount certificates. 210.6-08 Section 210.6-08... applicable to the statements of operations of issuers of face-amount certificates. Statements of operations filed by issuers of face-amount certificates shall comply with the following provisions: Statements of...

  13. Application modeling ipv6 (internet protocol version 6) on e-id card for identification number for effectiveness and efficiency of registration process identification of population

    NASA Astrophysics Data System (ADS)

    Pardede, A. M. H.; Maulita, Y.; Buaton, R.

    2018-03-01

    When someone wants to be registered in an institution such as Birth Certificate, School, Higher Education, e-ID card, Tax, BPJS, Bank, Driving License, Passport and others then have to register and do registration one by one and have registration number or account respectively agency. It may be said that everyone is bothered with the registration process, from the moment of birth must be registered to be registered as a resident, to enter the school must also registration, it is considered ineffective and efficient because one must continue to register one by one and there is repetition of ownership registration number which vary each agency. Seeing these problems need to find a solution or attempt how to keep the affairs of registration is not repetitive and quite once and the number applies to all agencies. The presence of the latest technology that IPv6 brings opportunities for the efficiency and effectiveness of the registration system. The method used in this research is the exploration and modeling of system development with NDLC (Network Development Life Cycle) to produce a model to build IPv6 implementation on e-ID card. The results of the study will show that the public has one registration number.

  14. 17 CFR 240.15g-6 - Account statements for penny stock customers.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Account statements for penny... § 240.15g-6 Account statements for penny stock customers. (a) Requirement. It shall be unlawful for any... pursuant to 17 CFR 240.15g-1, of any security that is a penny stock on the last trading day of any calendar...

  15. 17 CFR 240.15g-6 - Account statements for penny stock customers.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 4 2014-04-01 2014-04-01 false Account statements for penny... § 240.15g-6 Account statements for penny stock customers. (a) Requirement. It shall be unlawful for any... pursuant to 17 CFR 240.15g-1, of any security that is a penny stock on the last trading day of any calendar...

  16. 17 CFR 240.15g-6 - Account statements for penny stock customers.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 3 2012-04-01 2012-04-01 false Account statements for penny... § 240.15g-6 Account statements for penny stock customers. (a) Requirement. It shall be unlawful for any... pursuant to 17 CFR 240.15g-1, of any security that is a penny stock on the last trading day of any calendar...

  17. 17 CFR 240.15g-6 - Account statements for penny stock customers.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 3 2013-04-01 2013-04-01 false Account statements for penny... § 240.15g-6 Account statements for penny stock customers. (a) Requirement. It shall be unlawful for any... pursuant to 17 CFR 240.15g-1, of any security that is a penny stock on the last trading day of any calendar...

  18. 17 CFR 210.3-12 - Age of financial statements at effective date of registration statement or at mailing date of...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Age of financial statements at... FOR FINANCIAL STATEMENTS, SECURITIES ACT OF 1933, SECURITIES EXCHANGE ACT OF 1934, PUBLIC UTILITY... POLICY AND CONSERVATION ACT OF 1975 General Instructions As to Financial Statements § 210.3-12 Age of...

  19. 40 CFR 164.25 - Filing copies of notification of intent to cancel registration or change classification or...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... intent to cancel registration or change classification or refusal to register, and statement of issues. 164.25 Section 164.25 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE... ACT, ARISING FROM REFUSALS TO REGISTER, CANCELLATIONS OF REGISTRATIONS, CHANGES OF CLASSIFICATIONS...

  20. 12 CFR 584.1 - Registration, examination and reports.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Section 584.1 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY SAVINGS AND LOAN... loan holding company, each savings and loan holding company shall register with the OTS by filing a registration statement H-(b)10. (2) Filing of annual/current reports. Each registered savings and loan holding...

  1. 18 CFR 380.6 - Actions that require an environmental impact statement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... fields are used; (3) Major pipeline construction projects under section 7 of the Natural Gas Act using... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Actions that require an environmental impact statement. 380.6 Section 380.6 Conservation of Power and Water Resources FEDERAL ENERGY...

  2. 18 CFR 380.6 - Actions that require an environmental impact statement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... fields are used; (3) Major pipeline construction projects under section 7 of the Natural Gas Act using... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Actions that require an environmental impact statement. 380.6 Section 380.6 Conservation of Power and Water Resources FEDERAL ENERGY...

  3. 18 CFR 380.6 - Actions that require an environmental impact statement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... fields are used; (3) Major pipeline construction projects under section 7 of the Natural Gas Act using... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Actions that require an environmental impact statement. 380.6 Section 380.6 Conservation of Power and Water Resources FEDERAL ENERGY...

  4. 18 CFR 380.6 - Actions that require an environmental impact statement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... fields are used; (3) Major pipeline construction projects under section 7 of the Natural Gas Act using... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Actions that require an environmental impact statement. 380.6 Section 380.6 Conservation of Power and Water Resources FEDERAL ENERGY...

  5. 17 CFR 249.10 - Form 1-N for notice registration as a national securities exchange.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... registration as a national securities exchange. 249.10 Section 249.10 Commodity and Securities Exchanges... or Exemption of, and Notification of Action Taken by, National Securities Exchanges § 249.10 Form 1-N for notice registration as a national securities exchange. This form shall be used for notice, and...

  6. 14 CFR 47.15 - Registration number.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... REGISTRATION General § 47.15 Registration number. (a) Number required. An applicant for aircraft registration must place a U.S. registration number (registration mark) on the Aircraft Registration Application, AC... Dealer's Aircraft Registration Certificate, AC Form 8050-6, who applies for a temporary registration...

  7. 14 CFR 47.15 - Registration number.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... REGISTRATION General § 47.15 Registration number. (a) Number required. An applicant for aircraft registration must place a U.S. registration number (registration mark) on the Aircraft Registration Application, AC... Dealer's Aircraft Registration Certificate, AC Form 8050-6, who applies for a temporary registration...

  8. 14 CFR 47.15 - Registration number.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... REGISTRATION General § 47.15 Registration number. (a) Number required. An applicant for aircraft registration must place a U.S. registration number (registration mark) on the Aircraft Registration Application, AC... Dealer's Aircraft Registration Certificate, AC Form 8050-6, who applies for a temporary registration...

  9. 14 CFR 47.15 - Registration number.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... REGISTRATION General § 47.15 Registration number. (a) Number required. An applicant for aircraft registration must place a U.S. registration number (registration mark) on the Aircraft Registration Application, AC... Dealer's Aircraft Registration Certificate, AC Form 8050-6, who applies for a temporary registration...

  10. 17 CFR 240.15g-6 - Account statements for penny stock customers.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... stock customers. 240.15g-6 Section 240.15g-6 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... § 240.15g-6 Account statements for penny stock customers. (a) Requirement. It shall be unlawful for any broker or dealer that has effected the sale to any customer, other than in a transaction that is exempt...

  11. 40 CFR 164.25 - Filing copies of notification of intent to cancel registration or change classification or...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... intent to cancel registration or change classification or refusal to register, and statement of issues... copies of notification of intent to cancel registration or change classification or refusal to register... appropriate notice of intention to cancel, the notice of intention to change the classification or the...

  12. 28 CFR 5.206 - Language and wording of registration statement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... though it is in a foreign language if it is accompanied by an English translation certified under oath by... general purposes, as a true and accurate translation. (b) A statement, amendment, exhibit, or notice...

  13. 40 CFR 165.70 - Refillers who are not registrants.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... site of a user who intends to use or apply the product. (3) The registrant has entered into a written... changes except the addition of an appropriate net contents statement and the refillers EPA establishment... with the requirements of part 156 of this chapter. In particular, you must ensure that the net contents...

  14. 17 CFR 240.6a-4 - Notice of registration under Section 6(g) of the Act, amendment to such notice, and supplemental...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... this section is available continuously on an Internet web site controlled by a Security Futures Product... 17 Commodity and Securities Exchanges 3 2012-04-01 2012-04-01 false Notice of registration under... registered under Section 6(g) of the Act. 240.6a-4 Section 240.6a-4 Commodity and Securities Exchanges...

  15. 17 CFR 240.6a-4 - Notice of registration under Section 6(g) of the Act, amendment to such notice, and supplemental...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... this section is available continuously on an Internet web site controlled by a Security Futures Product... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Notice of registration under... registered under Section 6(g) of the Act. 240.6a-4 Section 240.6a-4 Commodity and Securities Exchanges...

  16. Do emergency medicine journals promote trial registration and adherence to reporting guidelines? A survey of "Instructions for Authors".

    PubMed

    Sims, Matthew T; Henning, Nolan M; Wayant, C Cole; Vassar, Matt

    2016-11-24

    The aim of this study was to evaluate the current state of two publication practices, reporting guidelines requirements and clinical trial registration requirements, by analyzing the "Instructions for Authors" of emergency medicine journals. We performed a web-based data abstraction from the "Instructions for Authors" of the 27 Emergency Medicine journals catalogued in the Expanded Science Citation Index of the 2014 Journal Citation Reports and Google Scholar Metrics h5-index to identify whether each journal required, recommended, or made no mention of the following reporting guidelines: EQUATOR Network, ICMJE, ARRIVE, CARE, CONSORT, STARD, TRIPOD, CHEERS, MOOSE, STROBE, COREQ, SRQR, SQUIRE, PRISMA-P, SPIRIT, PRISMA, and QUOROM. We also extracted whether journals required or recommended trial registration. Authors were blinded to one another's ratings until completion of the data validation. Cross-tabulations and descriptive statistics were calculated using IBM SPSS 22. Of the 27 emergency medicine journals, 11 (11/27, 40.7%) did not mention a single guideline within their "Instructions for Authors," while the remaining 16 (16/27, 59.3%) mentioned one or more guidelines. The QUOROM statement and SRQR were not mentioned by any journals whereas the ICMJE guidelines (18/27, 66.7%) and CONSORT statement (15/27, 55.6%) were mentioned most often. Of the 27 emergency medicine journals, 15 (15/27, 55.6%) did not mention trial or review registration, while the remaining 12 (12/27, 44.4%) at least mentioned one of the two. Trial registration through ClinicalTrials.gov was mentioned by seven (7/27, 25.9%) journals while the WHO registry was mentioned by four (4/27, 14.8%). Twelve (12/27, 44.4%) journals mentioned trial registration through any registry platform. The aim of this study was to evaluate the current state of two publication practices, reporting guidelines requirements and clinical trial registration requirements, by analyzing the "Instructions for Authors" of

  17. 16 CFR 1130.6 - Requirements for format of registration forms.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... manufacturer's name and mailing address where registration information is to be collected. (c) Font size and typeface. The registration form shall use bold black typeface. The size of the type shall be at least 12... information shall be in capital and lower case type. ...

  18. Consensus statement on blocking the effects of interleukin-6 and in particular by interleukin-6 receptor inhibition in rheumatoid arthritis and other inflammatory conditions

    PubMed Central

    Smolen, Josef S; Schoels, Monika M; Nishimoto, Norihiro; Breedveld, Ferdinand C; Burmester, Gerd R; Dougados, Maxime; Emery, Paul; Ferraccioli, Gianfranco; Gabay, Cem; Gibofsky, Allan; Gomez-Reino, Juan Jesus; Jones, Graeme; Kvien, Tore K; Murakami, Miho; Betteridge, Neil; Bingham, Clifton O; Bykerk, Vivian; Choy, Ernest H; Combe, Bernard; Cutolo, Maurizio; Graninger, Winfried; Lanas, Angel; Martin-Mola, Emilio; Montecucco, Carlomaurizio; Ostergaard, Mikkel; Pavelka, Karel; Rubbert-Roth, Andrea; Sattar, Naveed; Scholte-Voshaar, Marieke; Tanaka, Yoshiya; Trauner, Michael; Valentini, Gabriele; Winthrop, Kevin L; de Wit, Maarten; van der Heijde, Désirée

    2013-01-01

    Background Since approval of tocilizumab (TCZ) for treatment of rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA), interleukin 6 (IL-6) pathway inhibition was evaluated in trials of TCZ and other agents targeting the IL-6 receptor and ligand in various RA populations and other inflammatory diseases. This consensus document informs on interference with the IL-6 pathway based on evidence and expert opinion. Methods Preparation of this document involved international experts in RA treatment and RA patients. A systematic literature search was performed that focused on TCZ and other IL6-pathway inhibitors in RA and other diseases. Subsequently, incorporating available published evidence and expert opinion, the steering committee and a broader expert committee (both including RA patients) formulated the current consensus statement. Results The consensus statement covers use of TCZ as combination- or monotherapy in various RA populations and includes clinical, functional and structural aspects. The statement also addresses the second approved indication in Europe JIA and non-approved indications. Also early phase trials involving additional agents that target the IL-6 receptor or IL-6 were evaluated. Safety concerns, including haematological, hepatic and metabolic issues as well as infections, are addressed likewise. Conclusions The consensus statement identifies points to consider when using TCZ, regarding indications, contraindications, screening, dose, comedication, response evaluation and safety. The document is aimed at supporting clinicians and informing patients, administrators and payers on opportunities and limitations of IL-6 pathway inhibition. PMID:23172750

  19. 17 CFR 210.3A-02 - Consolidated financial statements of the registrant and its subsidiaries.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 2 2011-04-01 2011-04-01 false Consolidated financial... Exchanges SECURITIES AND EXCHANGE COMMISSION FORM AND CONTENT OF AND REQUIREMENTS FOR FINANCIAL STATEMENTS... 1975 Consolidated and Combined Financial Statements § 210.3A-02 Consolidated financial statements of...

  20. 17 CFR 210.3A-02 - Consolidated financial statements of the registrant and its subsidiaries.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 1975 Consolidated and Combined Financial Statements § 210.3A-02 Consolidated financial statements of... consolidated financial statements principles of inclusion or exclusion which will clearly exhibit the financial... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Consolidated financial...

  1. 17 CFR 230.484 - Undertaking required in certain registration statements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... statement is prepared on a form available solely to investment companies registered under the investment... and an undertaking in substantially the following form: Insofar as indemnification for liability..., suit or proceeding) is asserted by such director, officer or controlling person in connection with the...

  2. 17 CFR 230.484 - Undertaking required in certain registration statements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... statement is prepared on a form available solely to investment companies registered under the investment... and an undertaking in substantially the following form: Insofar as indemnification for liability..., suit or proceeding) is asserted by such director, officer or controlling person in connection with the...

  3. 17 CFR 230.484 - Undertaking required in certain registration statements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... statement is prepared on a form available solely to investment companies registered under the investment... and an undertaking in substantially the following form: Insofar as indemnification for liability..., suit or proceeding) is asserted by such director, officer or controlling person in connection with the...

  4. 17 CFR 230.484 - Undertaking required in certain registration statements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... statement is prepared on a form available solely to investment companies registered under the investment... and an undertaking in substantially the following form: Insofar as indemnification for liability..., suit or proceeding) is asserted by such director, officer or controlling person in connection with the...

  5. 17 CFR 210.6-08 - Special provisions applicable to the statements of operations of issuers of face-amount...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... to the statements of operations of issuers of face-amount certificates. 210.6-08 Section 210.6-08... issuers of face-amount certificates. Statements of operations filed by issuers of face-amount certificates... included in income, the bases of recognition and measurement used in respect to such amounts shall be...

  6. 17 CFR 210.6-08 - Special provisions applicable to the statements of operations of issuers of face-amount...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... to the statements of operations of issuers of face-amount certificates. 210.6-08 Section 210.6-08... issuers of face-amount certificates. Statements of operations filed by issuers of face-amount certificates... included in income, the bases of recognition and measurement used in respect to such amounts shall be...

  7. 17 CFR 210.6-08 - Special provisions applicable to the statements of operations of issuers of face-amount...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... to the statements of operations of issuers of face-amount certificates. 210.6-08 Section 210.6-08... issuers of face-amount certificates. Statements of operations filed by issuers of face-amount certificates... included in income, the bases of recognition and measurement used in respect to such amounts shall be...

  8. Sulcal set optimization for cortical surface registration.

    PubMed

    Joshi, Anand A; Pantazis, Dimitrios; Li, Quanzheng; Damasio, Hanna; Shattuck, David W; Toga, Arthur W; Leahy, Richard M

    2010-04-15

    Flat mapping based cortical surface registration constrained by manually traced sulcal curves has been widely used for inter subject comparisons of neuroanatomical data. Even for an experienced neuroanatomist, manual sulcal tracing can be quite time consuming, with the cost increasing with the number of sulcal curves used for registration. We present a method for estimation of an optimal subset of size N(C) from N possible candidate sulcal curves that minimizes a mean squared error metric over all combinations of N(C) curves. The resulting procedure allows us to estimate a subset with a reduced number of curves to be traced as part of the registration procedure leading to optimal use of manual labeling effort for registration. To minimize the error metric we analyze the correlation structure of the errors in the sulcal curves by modeling them as a multivariate Gaussian distribution. For a given subset of sulci used as constraints in surface registration, the proposed model estimates registration error based on the correlation structure of the sulcal errors. The optimal subset of constraint curves consists of the N(C) sulci that jointly minimize the estimated error variance for the subset of unconstrained curves conditioned on the N(C) constraint curves. The optimal subsets of sulci are presented and the estimated and actual registration errors for these subsets are computed. Copyright 2009 Elsevier Inc. All rights reserved.

  9. 76 FR 66995 - David T. Koon, M.D.; Revocation of Registration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-28

    ... Registration, BK4092350, as a practitioner, and the denial of any applications to renew or modify the... submitted a statement. Because more than thirty days have passed since service of the Show Cause Order, I... United States or the jurisdiction in which he practices * * * to distribute, dispense * * * [or...

  10. 77 FR 8298 - Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-14

    ... registration statements (see the separate PRA submissions for Form N-3 (3235-0316), Form N-4 (3235-0318) and Form N-6 (3235-0503). The Commission is requesting a burden of one hour for Rule 11a-2 for... submissions for Form N-3, Form N-4 and Form N-6). The information collection requirements imposed by Rule 11a...

  11. 14 CFR 47.16 - Temporary registration numbers.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... AIRCRAFT REGISTRATION General § 47.16 Temporary registration numbers. (a) Temporary registration numbers... Registration Certificates, AC Form 8050-6, for temporary display on aircraft during flight allowed under Subpart C of this part. (b) The holder of a Dealer's Aircraft Registration Certificate may apply to the...

  12. 14 CFR 47.16 - Temporary registration numbers.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... AIRCRAFT REGISTRATION General § 47.16 Temporary registration numbers. (a) Temporary registration numbers... Registration Certificates, AC Form 8050-6, for temporary display on aircraft during flight allowed under Subpart C of this part. (b) The holder of a Dealer's Aircraft Registration Certificate may apply to the...

  13. 14 CFR 47.16 - Temporary registration numbers.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... AIRCRAFT REGISTRATION General § 47.16 Temporary registration numbers. (a) Temporary registration numbers... Registration Certificates, AC Form 8050-6, for temporary display on aircraft during flight allowed under Subpart C of this part. (b) The holder of a Dealer's Aircraft Registration Certificate may apply to the...

  14. 14 CFR 47.16 - Temporary registration numbers.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... AIRCRAFT REGISTRATION General § 47.16 Temporary registration numbers. (a) Temporary registration numbers... Registration Certificates, AC Form 8050-6, for temporary display on aircraft during flight allowed under Subpart C of this part. (b) The holder of a Dealer's Aircraft Registration Certificate may apply to the...

  15. Prospective registration trends, reasons for retrospective registration and mechanisms to increase prospective registration compliance: descriptive analysis and survey.

    PubMed

    Hunter, Kylie Elizabeth; Seidler, Anna Lene; Askie, Lisa M

    2018-03-01

    To analyse prospective versus retrospective trial registration trends on the Australian New Zealand Clinical Trials Registry (ANZCTR) and to evaluate the reasons for non-compliance with prospective registration. Part 1: Descriptive analysis of trial registration trends from 2006 to 2015. Part 2: Online registrant survey. Part 1: All interventional trials registered on ANZCTR from 2006 to 2015. Part 2: Random sample of those who had retrospectively registered a trial on ANZCTR between 2010 and 2015. Part 1: Proportion of prospective versus retrospective clinical trial registrations (ie, registration before versus after enrolment of the first participant) on the ANZCTR overall and by various key metrics, such as sponsor, funder, recruitment country and sample size. Part 2: Reasons for non-compliance with prospective registration and perceived usefulness of various proposed mechanisms to improve prospective registration compliance. Part 1: Analysis of the complete dataset of 9450 trials revealed that compliance with prospective registration increased from 48% (216 out of 446 trials) in 2006 to 63% (723/1148) in 2012 and has since plateaued at around 64%. Patterns of compliance were relatively consistent across sponsor and funder types (industry vs non-industry), type of intervention (drug vs non-drug) and size of trial (n<100, 100-500, >500). However, primary sponsors from Australia/New Zealand were almost twice as likely to register prospectively (62%; 4613/7452) compared with sponsors from other countries with a WHO Network Registry (35%; 377/1084) or sponsors from countries without a WHO Registry (29%; 230/781). Part 2: The majority (56%; 84/149) of survey respondents cited lack of awareness as a reason for not registering their study prospectively. Seventy-four per cent (111/149) stated that linking registration to ethics approval would facilitate prospective registration. Despite some progress, compliance with prospective registration remains suboptimal. Linking

  16. Prospective registration trends, reasons for retrospective registration and mechanisms to increase prospective registration compliance: descriptive analysis and survey

    PubMed Central

    Seidler, Anna Lene; Askie, Lisa M

    2018-01-01

    Objectives To analyse prospective versus retrospective trial registration trends on the Australian New Zealand Clinical Trials Registry (ANZCTR) and to evaluate the reasons for non-compliance with prospective registration. Design Part 1: Descriptive analysis of trial registration trends from 2006 to 2015. Part 2: Online registrant survey. Participants Part 1: All interventional trials registered on ANZCTR from 2006 to 2015. Part 2: Random sample of those who had retrospectively registered a trial on ANZCTR between 2010 and 2015. Main outcome measures Part 1: Proportion of prospective versus retrospective clinical trial registrations (ie, registration before versus after enrolment of the first participant) on the ANZCTR overall and by various key metrics, such as sponsor, funder, recruitment country and sample size. Part 2: Reasons for non-compliance with prospective registration and perceived usefulness of various proposed mechanisms to improve prospective registration compliance. Results Part 1: Analysis of the complete dataset of 9450 trials revealed that compliance with prospective registration increased from 48% (216 out of 446 trials) in 2006 to 63% (723/1148) in 2012 and has since plateaued at around 64%. Patterns of compliance were relatively consistent across sponsor and funder types (industry vs non-industry), type of intervention (drug vs non-drug) and size of trial (n<100, 100–500, >500). However, primary sponsors from Australia/New Zealand were almost twice as likely to register prospectively (62%; 4613/7452) compared with sponsors from other countries with a WHO Network Registry (35%; 377/1084) or sponsors from countries without a WHO Registry (29%; 230/781). Part 2: The majority (56%; 84/149) of survey respondents cited lack of awareness as a reason for not registering their study prospectively. Seventy-four per cent (111/149) stated that linking registration to ethics approval would facilitate prospective registration. Conclusions Despite some

  17. 17 CFR 239.33 - Form F-3, for registration under the Securities Act of 1933 of securities of certain foreign...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 2 2012-04-01 2012-04-01 false Form F-3, for registration... CFR 230.405); or (v) Discloses in the registration statement that it has a reasonable belief that it... offering of non-convertible investment grade securities, discloses the basis for such belief, and files a...

  18. 17 CFR 239.33 - Form F-3, for registration under the Securities Act of 1933 of securities of certain foreign...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 3 2014-04-01 2014-04-01 false Form F-3, for registration... CFR 230.405); or (v) Discloses in the registration statement that it has a reasonable belief that it... offering of non-convertible investment grade securities, discloses the basis for such belief, and files a...

  19. 17 CFR 239.33 - Form F-3, for registration under the Securities Act of 1933 of securities of certain foreign...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 2 2013-04-01 2013-04-01 false Form F-3, for registration... CFR 230.405); or (v) Discloses in the registration statement that it has a reasonable belief that it... offering of non-convertible investment grade securities, discloses the basis for such belief, and files a...

  20. PRN Notice 96-6: Pet Pesticide Product Label Statements

    EPA Pesticide Factsheets

    This notice specifies statements that should be added to the labels of pesticide products registered for use on dogs and/or cats. These label statements will help to ensure that products bear labeling to reduce the potential for misuse of pet products.

  1. 17 CFR 249.802 - Form X-15AJ-1, for amendatory and/or supplementary statements to registration statement of a...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... EXCHANGE COMMISSION (CONTINUED) FORMS, SECURITIES EXCHANGE ACT OF 1934 Forms for Self-Regulatory Organization Rule Changes and Forms for Registration of and Reporting by National Securities Associations and...

  2. 17 CFR 249.802 - Form X-15AJ-1, for amendatory and/or supplementary statements to registration statement of a...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... EXCHANGE COMMISSION (CONTINUED) FORMS, SECURITIES EXCHANGE ACT OF 1934 Forms for Self-Regulatory Organization Rule Changes and Forms for Registration of and Reporting by National Securities Associations and...

  3. 17 CFR 249.802 - Form X-15AJ-1, for amendatory and/or supplementary statements to registration statement of a...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... EXCHANGE COMMISSION (CONTINUED) FORMS, SECURITIES EXCHANGE ACT OF 1934 Forms for Self-Regulatory Organization Rule Changes and Forms for Registration of and Reporting by National Securities Associations and...

  4. 17 CFR 249.802 - Form X-15AJ-1, for amendatory and/or supplementary statements to registration statement of a...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... EXCHANGE COMMISSION (CONTINUED) FORMS, SECURITIES EXCHANGE ACT OF 1934 Forms for Self-Regulatory Organization Rule Changes and Forms for Registration of and Reporting by National Securities Associations and...

  5. 17 CFR 249.802 - Form X-15AJ-1, for amendatory and/or supplementary statements to registration statement of a...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... EXCHANGE COMMISSION (CONTINUED) FORMS, SECURITIES EXCHANGE ACT OF 1934 Forms for Self-Regulatory Organization Rule Changes and Forms for Registration of and Reporting by National Securities Associations and...

  6. A prospective comparison between auto-registration and manual registration of real-time ultrasound with MR images for percutaneous ablation or biopsy of hepatic lesions.

    PubMed

    Cha, Dong Ik; Lee, Min Woo; Song, Kyoung Doo; Oh, Young-Taek; Jeong, Ja-Yeon; Chang, Jung-Woo; Ryu, Jiwon; Lee, Kyong Joon; Kim, Jaeil; Bang, Won-Chul; Shin, Dong Kuk; Choi, Sung Jin; Koh, Dalkwon; Seo, Bong Koo; Kim, Kyunga

    2017-06-01

    To compare the accuracy and required time for image fusion of real-time ultrasound (US) with pre-procedural magnetic resonance (MR) images between positioning auto-registration and manual registration for percutaneous radiofrequency ablation or biopsy of hepatic lesions. This prospective study was approved by the institutional review board, and all patients gave written informed consent. Twenty-two patients (male/female, n = 18/n = 4; age, 61.0 ± 7.7 years) who were referred for planning US to assess the feasibility of radiofrequency ablation (n = 21) or biopsy (n = 1) for focal hepatic lesions were included. One experienced radiologist performed the two types of image fusion methods in each patient. The performance of auto-registration and manual registration was evaluated. The accuracy of the two methods, based on measuring registration error, and the time required for image fusion for both methods were recorded using in-house software and respectively compared using the Wilcoxon signed rank test. Image fusion was successful in all patients. The registration error was not significantly different between the two methods (auto-registration: median, 3.75 mm; range, 1.0-15.8 mm vs. manual registration: median, 2.95 mm; range, 1.2-12.5 mm, p = 0.242). The time required for image fusion was significantly shorter with auto-registration than with manual registration (median, 28.5 s; range, 18-47 s, vs. median, 36.5 s; range, 14-105 s, p = 0.026). Positioning auto-registration showed promising results compared with manual registration, with similar accuracy and even shorter registration time.

  7. 37 CFR 1.293 - Statutory invention registration.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... the date of publication of the statutory invention registration; (2) The required fee for filing a request for publication of a statutory invention registration as provided for in § 1.17 (n) or (o); (3) A... application. (b) Any request for publication of a statutory invention registration must include the following...

  8. Guidance to Registrants: Process for Making Claims Against Emerging Viral Pathogens not on EPA-Registered Disinfectant Labels

    EPA Pesticide Factsheets

    This guidance proposes to use an organism hierarchy to identify effective products for use with emerging pathogens and to permit registrants to make limited statements against such pathogens. It provides general guidance to interested parties.

  9. 76 FR 10291 - Amendment to the International Traffic in Arms Regulations: Electronic Payment of Registration...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-24

    ..., Bureau of Political Military Affairs, U.S. Department of State, Washington, DC 20522-0112. Persons with... DS-2032, Statement of Registration, submission) certifying criminal history, eligibility, and foreign... Office: Bureau of Political-Military Affairs, Directorate of Defense Trade Controls, PM/DDTC. Form Number...

  10. 17 CFR 239.24 - Form N-5, form for registration of small business investment company under the Securities Act of...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... registration of small business investment company under the Securities Act of 1933 and the Investment Company... N-5, form for registration of small business investment company under the Securities Act of 1933 and... of 1933 of securities issued by any small business investment company which is registered under the...

  11. PRN 93-8: Labeling Statement Prohibiting Application to Water; Amendment to PR Notice 93-3

    EPA Pesticide Factsheets

    This notice adds one paragraph to P.R. Notice 93-3, which requested registrants to amend product labeling to include a new labeling statement prohibiting application of a pesticide to water for certain products.

  12. Endorsement of the CONSORT Statement by High-Impact Medical Journals in China: A Survey of Instructions for Authors and Published Papers

    PubMed Central

    Zhou, Qing-hui; Moher, David; Chen, Hong-yun; Wang, Fu-zhe; Ling, Chang-quan

    2012-01-01

    Background The CONSORT Statement is a reporting guideline for authors when reporting randomized controlled trials (RCTs). It offers a standard way for authors to prepare RCT reports. It has been endorsed by many high-impact medical journals and by international editorial groups. This study was conducted to assess the endorsement of the CONSORT Statement by high-impact medical journals in China by reviewing their instructions for authors. Methodology/Principal Findings A total of 200 medical journals were selected according to the Chinese Science and Technology Journal Citation Reports, 195 of which publish clinical research papers. Their instructions for authors were reviewed and all texts mentioning the CONSORT Statement or CONSORT extension papers were extracted. Any mention of the Uniform Requirements for Manuscripts Submitted to Biomedical Journals (URM) developed by the International Committee of Medical Journal Editors (ICMJE) or ‘clinical trial registration’ was also extracted. For journals endorsing the CONSORT Statement, their most recently published RCT reports were retrieved and evaluated to assess whether the journals have followed what the CONSORT Statement required. Out of the 195 medical journals publishing clinical research papers, only six (6/195, 3.08%) mentioned ‘CONSORT’ in their instructions for authors; out of the 200 medical journals surveyed, only 14 (14/200, 7.00%) mentioned ‘ICMJE’ or ‘URM’ in their instructions for authors, and another five journals stated in their instructions for authors that clinical trials should have trial registration numbers and that priority would be given to clinical trials which had been registered. Among the 62 RCT reports published in the six journals endorsing the CONSORT Statement, 20 (20/62, 32.26%) contained flow diagrams and only three (3/62, 4.84%) provided trial registration information. Conclusions/Significance Medical journals in China endorsing either the CONSORT Statement or the

  13. 26 CFR 1.613-6 - Statement to be attached to return when depletion is claimed on percentage basis.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 7 2010-04-01 2010-04-01 true Statement to be attached to return when depletion....613-6 Statement to be attached to return when depletion is claimed on percentage basis. In addition to... depletion deduction under section 613 for any taxable year shall attach to his return for such year a...

  14. 9 CFR 151.6 - Statement of owner, agent, or importer as to identity of animals.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Statement of owner, agent, or importer as to identity of animals. 151.6 Section 151.6 Animals and Animal Products ANIMAL AND PLANT HEALTH... identity of animals. The owner, agent, or importer who applies for a certificate of pure breeding for any...

  15. 9 CFR 151.6 - Statement of owner, agent, or importer as to identity of animals.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Statement of owner, agent, or importer as to identity of animals. 151.6 Section 151.6 Animals and Animal Products ANIMAL AND PLANT HEALTH... identity of animals. The owner, agent, or importer who applies for a certificate of pure breeding for any...

  16. 9 CFR 151.6 - Statement of owner, agent, or importer as to identity of animals.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Statement of owner, agent, or importer as to identity of animals. 151.6 Section 151.6 Animals and Animal Products ANIMAL AND PLANT HEALTH... identity of animals. The owner, agent, or importer who applies for a certificate of pure breeding for any...

  17. 31 CFR 360.6 - Authorized forms of registration.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Service annuitant, pursuant to 5 U.S.C. 8345(e). John F. Green or Mary B. Doe, Trustees of the Estate of... ownership form. A bond may be registered in the name of one individual. Example: Julie B. Jones, 123-45-6789... coowners. The form of registration “A and B” is not authorized. Examples: David R. Johnson 123-45-6789 or...

  18. 17 CFR 210.3-16 - Financial statements of affiliates whose securities collateralize an issue registered or being...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... POLICY AND CONSERVATION ACT OF 1975 General Instructions As to Financial Statements § 210.3-16 Financial... the securities as carried by the registrant, or the market value of such securities, whichever is the...

  19. Position Statement on Active Outdoor Play

    PubMed Central

    Tremblay, Mark S.; Gray, Casey; Babcock, Shawna; Barnes, Joel; Costas Bradstreet, Christa; Carr, Dawn; Chabot, Guylaine; Choquette, Louise; Chorney, David; Collyer, Cam; Herrington, Susan; Janson, Katherine; Janssen, Ian; Larouche, Richard; Pickett, William; Power, Marlene; Sandseter, Ellen Beate Hansen; Simon, Brenda; Brussoni, Mariana

    2015-01-01

    A diverse, cross-sectorial group of partners, stakeholders and researchers, collaborated to develop an evidence-informed Position Statement on active outdoor play for children aged 3–12 years. The Position Statement was created in response to practitioner, academic, legal, insurance and public debate, dialogue and disagreement on the relative benefits and harms of active (including risky) outdoor play. The Position Statement development process was informed by two systematic reviews, a critical appraisal of the current literature and existing position statements, engagement of research experts (N = 9) and cross-sectorial individuals/organizations (N = 17), and an extensive stakeholder consultation process (N = 1908). More than 95% of the stakeholders consulted strongly agreed or somewhat agreed with the Position Statement; 14/17 participating individuals/organizations endorsed it; and over 1000 additional individuals and organizations requested their name be listed as a supporter. The final Position Statement on Active Outdoor Play states: “Access to active play in nature and outdoors—with its risks— is essential for healthy child development. We recommend increasing children’s opportunities for self-directed play outdoors in all settings—at home, at school, in child care, the community and nature.” The full Position Statement provides context for the statement, evidence supporting it, and a series of recommendations to increase active outdoor play opportunities to promote healthy child development. PMID:26062040

  20. Position Statement on Active Outdoor Play.

    PubMed

    Tremblay, Mark S; Gray, Casey; Babcock, Shawna; Barnes, Joel; Bradstreet, Christa Costas; Carr, Dawn; Chabot, Guylaine; Choquette, Louise; Chorney, David; Collyer, Cam; Herrington, Susan; Janson, Katherine; Janssen, Ian; Larouche, Richard; Pickett, William; Power, Marlene; Sandseter, Ellen Beate Hansen; Simon, Brenda; Brussoni, Mariana

    2015-06-08

    A diverse, cross-sectorial group of partners, stakeholders and researchers, collaborated to develop an evidence-informed Position Statement on active outdoor play for children aged 3-12 years. The Position Statement was created in response to practitioner, academic, legal, insurance and public debate, dialogue and disagreement on the relative benefits and harms of active (including risky) outdoor play. The Position Statement development process was informed by two systematic reviews, a critical appraisal of the current literature and existing position statements, engagement of research experts (N=9) and cross-sectorial individuals/organizations (N=17), and an extensive stakeholder consultation process (N=1908). More than 95% of the stakeholders consulted strongly agreed or somewhat agreed with the Position Statement; 14/17 participating individuals/organizations endorsed it; and over 1000 additional individuals and organizations requested their name be listed as a supporter. The final Position Statement on Active Outdoor Play states: "Access to active play in nature and outdoors--with its risks--is essential for healthy child development. We recommend increasing children's opportunities for self-directed play outdoors in all settings--at home, at school, in child care, the community and nature." The full Position Statement provides context for the statement, evidence supporting it, and a series of recommendations to increase active outdoor play opportunities to promote healthy child development.

  1. Skull registration for prone patient position using tracked ultrasound

    NASA Astrophysics Data System (ADS)

    Underwood, Grace; Ungi, Tamas; Baum, Zachary; Lasso, Andras; Kronreif, Gernot; Fichtinger, Gabor

    2017-03-01

    PURPOSE: Tracked navigation has become prevalent in neurosurgery. Problems with registration of a patient and a preoperative image arise when the patient is in a prone position. Surfaces accessible to optical tracking on the back of the head are unreliable for registration. We investigated the accuracy of surface-based registration using points accessible through tracked ultrasound. Using ultrasound allows access to bone surfaces that are not available through optical tracking. Tracked ultrasound could eliminate the need to work (i) under the table for registration and (ii) adjust the tracker between surgery and registration. In addition, tracked ultrasound could provide a non-invasive method in comparison to an alternative method of registration involving screw implantation. METHODS: A phantom study was performed to test the feasibility of tracked ultrasound for registration. An initial registration was performed to partially align the pre-operative computer tomography data and skull phantom. The initial registration was performed by an anatomical landmark registration. Surface points accessible by tracked ultrasound were collected and used to perform an Iterative Closest Point Algorithm. RESULTS: When the surface registration was compared to a ground truth landmark registration, the average TRE was found to be 1.6+/-0.1mm and the average distance of points off the skull surface was 0.6+/-0.1mm. CONCLUSION: The use of tracked ultrasound is feasible for registration of patients in prone position and eliminates the need to perform registration under the table. The translational component of error found was minimal. Therefore, the amount of TRE in registration is due to a rotational component of error.

  2. 78 FR 30800 - Reopening of Comment Periods for Certain Proposed Rulemaking Releases and Policy Statements...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-23

    ..., among other things: (1) The registration and comprehensive oversight of security-based swap dealers and... SECURITIES AND EXCHANGE COMMISSION 17 CFR Parts 240, 242, and 249 [Release No. 34-69491; File Nos... Releases and Policy Statements Applicable to Security-Based Swaps AGENCY: Securities and Exchange...

  3. 18 CFR 380.6 - Actions that require an environmental impact statement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Federal action significantly affecting the quality of the human environment, an environmental assessment... environmental assessment, an environmental impact statement may or may not be prepared. (c) An environmental impact statement will not be required if an environmental assessment indicates that a proposal has...

  4. Survey of Non-Rigid Registration Tools in Medicine.

    PubMed

    Keszei, András P; Berkels, Benjamin; Deserno, Thomas M

    2017-02-01

    We catalogue available software solutions for non-rigid image registration to support scientists in selecting suitable tools for specific medical registration purposes. Registration tools were identified using non-systematic search in Pubmed, Web of Science, IEEE Xplore® Digital Library, Google Scholar, and through references in identified sources (n = 22). Exclusions are due to unavailability or inappropriateness. The remaining (n = 18) tools were classified by (i) access and technology, (ii) interfaces and application, (iii) living community, (iv) supported file formats, and (v) types of registration methodologies emphasizing the similarity measures implemented. Out of the 18 tools, (i) 12 are open source, 8 are released under a permissive free license, which imposes the least restrictions on the use and further development of the tool, 8 provide graphical processing unit (GPU) support; (ii) 7 are built on software platforms, 5 were developed for brain image registration; (iii) 6 are under active development but only 3 have had their last update in 2015 or 2016; (iv) 16 support the Analyze format, while 7 file formats can be read with only one of the tools; and (v) 6 provide multiple registration methods and 6 provide landmark-based registration methods. Based on open source, licensing, GPU support, active community, several file formats, algorithms, and similarity measures, the tools Elastics and Plastimatch are chosen for the platform ITK and without platform requirements, respectively. Researchers in medical image analysis already have a large choice of registration tools freely available. However, the most recently published algorithms may not be included in the tools, yet.

  5. Notification: Background Investigation Services Audits of EPA’s Fiscal Year 2015 FIFRA and PRIA Financial Statements

    EPA Pesticide Factsheets

    Projects #OA-FY16-0080 and #OA-FY16-0079, February 8, 2016. EPA OIG plan to begin audits of the EPA's fiscal year (FY) 2015 financial statements for the Pesticides Reregistration and Expedited Processing Fund (FIFRA) and Pesticide Registration Fund (PRIA).

  6. Alkylation of 6-mercaptopurine (6-MP) with N-alkyl-N-alkoxycarbonylaminomethyl chlorides: S6-(N-alkyl-N-alkoxycarbonyl)aminomethyl-6-MP prodrug structure effect on the dermal delivery of 6-MP.

    PubMed

    Siver, K G; Sloan, K B

    1990-01-01

    The S6-(N-alkyl-N-alkoxycarbonyl)aminomethyl-6-MP (6-CARB-6-MP) prodrugs 5-20 were synthesized from the reaction of 6-MP with N-alkyl-N-alkyoxycarbonylaminomethyl chlorides (4) in dimethyl sulfoxide in overall yields of 5-62%, depending on the N-alkyl and the alkoxy groups involved. The derivatives were fully characterized by spectral and microanalyses. The assignment of the substitution pattern as S6-alkyl was based on comparisons of the UV, 1H NMR and 13C NMR spectra with model compounds. A S6, 9-bis-alkyl derivative was obtained from the reaction of 2 equivalents of 4 with 6-MP but the product was unstable and decomposed on standing to a 9-alkyl derivative. The 6-CARB-6-MP prodrugs reverted to 6-MP in water by an SN1-type mechanism involving unimolecular charge separation in the transition state of the rate determining step. There was no effect of dermal enzymes on the rate of hydrolysis. The solubilities in isopropyl myristate (IPM) for all of the 6-CARB-6-MP prodrugs were significantly greater than the solubility of 6-MP in IPM but only one prodrug (5) was apparently even as soluble as 6-MP in water. Selected 6-CARB-6-MP prodrugs were examined in diffusion cell experiments. Only the N-methyl-N-methoxycarbonyl derivative 5 gave a steady-state rate of delivery of 6-MP from IPM that was significantly greater than the steady-state rate of delivery of 6-MP from 6-MP in IPM. All the other derivatives gave steady-state rates of delivery of 6-MP from IPM that were either not significantly different, or were significantly lower than the rate obtained from 6-MP in IPM. In all cases, the effect of the 6-CARB-6-MP:IPM suspensions on the permeability of the skin, as determined by the second application flux of theophylline:propylene glycol, was of the same magnitude as the effect of IPM alone.

  7. The Process for the Formulation of the International Telehealth Position Statement for Occupational Therapy

    PubMed Central

    JACOBS, KAREN; CASON, JANA; MCCULLOUGH, ANN

    2015-01-01

    The World Federation of Occupational Therapists (WFOT) consists of 84 member organizations representing over 420,000 occupational therapists internationally (WFOT, 2014). In 2014, WFOT published the WFOT Telehealth Position Statement on the use of telehealth in occupational therapy. The process for the formulation of the official document involved reviewing WFOT member organizations’ telehealth position statements and data collected from a survey sent to member organizations’ delegates in April 2014. Qualitative data from 39 countries yielded factors to consider in five key areas: licensure/registration requirements, the cost of technology, privacy and security, reimbursement/payment models, and other issues (e.g., need for collaboration/transfer of knowledge, client selection, provider competencies, standard of care). The WFOT Telehealth Position Statement addressed each of these areas. The collaborative effort resulting in the development of the WFOT Telehealth Position Statement serves as a model for other international organizations. PMID:27563380

  8. The European Federation of Organisations for Medical Physics Policy Statement No. 10.1: Recommended Guidelines on National Schemes for Continuing Professional Development of Medical Physicists.

    PubMed

    Christofides, Stelios; Isidoro, Jorge; Pesznyak, Csilla; Cremers, Florian; Figueira, Rita; van Swol, Christiaan; Evans, Stephen; Torresin, Alberto

    2016-01-01

    Continuing Professional Development (CPD) is vital to the medical physics profession if it is to embrace the pace of change occurring in medical practice. As CPD is the planned acquisition of knowledge, experience and skills required for professional practice throughout one's working life it promotes excellence and protects the profession and public against incompetence. Furthermore, CPD is a recommended prerequisite of registration schemes (Caruana et al. 2014) and is implied in the Council Directive 2013/59/EURATOM (EU BSS) and the International Basic Safety Standards (BSS). It is to be noted that currently not all national registration schemes require CPD to maintain the registration status necessary to practise medical physics. Such schemes should consider adopting CPD as a prerequisite for renewing registration after a set period of time. This EFOMP Policy Statement, which is an amalgamation and an update of the EFOMP Policy Statements No. 8 and No. 10, presents guidelines for the establishment of national schemes for CPD and activities that should be considered for CPD. Copyright © 2016. Published by Elsevier Ltd.

  9. 26 CFR 1.613-6 - Statement to be attached to return when depletion is claimed on percentage basis.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 7 2011-04-01 2009-04-01 true Statement to be attached to return when depletion is claimed on percentage basis. 1.613-6 Section 1.613-6 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Natural Resources § 1...

  10. Functional food and nutraceutical registration processes in Japan and China: a diffusion of innovation perspective.

    PubMed

    Patel, Darshika; Dufour, Yvon; Domigan, Neil

    2008-01-01

    Purpose - This paper looks into the functional food and nutraceutical registration processes in Japan and China. The Japanese have developed the Foods for Specified Health Use (FOSHU) registration process whereas the Chinese have put into place the Health Food (HF) registration process. The aim of this paper is to compare the regulation processes between the two countries in search for answers to three core empirical questions: (1) how have the registration processes developed and changed? (2) What are the similarities and differences between the processes of registration in the two countries investigated? (3) Why are the registration processes similar/different? Method - The study was conducted using secondary sources. The literature surveyed covered academic journals, trade journals, magazine and newspaper articles, market reports, proceedings, books and web pages of relevant regulatory authorities and regulatory consultants. Information from the more recently published sources was used preferentially over older sources. As well as using the most recent sources, information was selected on the basis of which source it was from. Official regulations and SFDA and MHLW websites would contain accurate and up to date information and information from here would be taken as true over other sources of information. Results - The two diagrams of the registration processes respectively in Japan and China clearly show that there are similarities and differences. There are six categories under which these can be found: (1) the scientific evidence required; (2) the application process; (3) the evaluation process; (4) the law and the categories of products; (5) the labels and the types of claims; and finally (6) the cost and the time involved. Conclusions -The data analysis suggests that the process of diffusion of innovation played a role in the development of the regulations. Further it was found that while Japan was at the outset a pioneer innovator in nutraceutical

  11. N6-Trimethyl-lysine metabolism. 3-Hydroxy-N6-trimethyl-lysine and carnitine biosynthesis.

    PubMed Central

    Hoppel, C L; Cox, R A; Novak, R F

    1980-01-01

    Rats injected with N6-[Me-3H]trimethyl-lysine excrete in the urine five radioactively labelled metabolites. Two of these identified metabolites are carnitine and 4-trimethylammoniobutyrate. A third metabolite, identified as 5-trimethylammoniopentanoate, is not an intermediate in the biosynthesis of carnitine; the fourth and major metabolite, N2-acetyl-N6-trimethyl-lysine, is not a precursor of carnitine. The remaining metabolite (3-hydroxy-N6-trimethyl-lysine) is converted into trimethylammoniobutyrate and carnitine by rat liver slices and into trimethylammoniobutyrate by rat kidney slices. In rat liver and kidney-slice experiments, radioactivity from DL-N6-trimethyl-[1-14C]lysine and DL-N6-trimethyl-[2-14C]lysine was incorporated into N2-acetyl-N6-trimethyl-lysine and 3-hydroxy-N6-trimethyl-lysine, but not into trimethylammoniobutyrate or carnitine. A procedure was devised to purify milligram quantities of 3-hydroxy-N6-trimethyl-lysine from the urine of rats injected chronically with N6-trimethyl-lysine (100 mg/kg body wt. per day). The structure of 3-hydroxy-N6-trimethyl-lysine was confirmed chemically and by nuclear-magnetic-resonance spectrometry [Novak, Swift & Hoppel (1980) Biochem. J. 188, 521--527]. The sequence for carnitine biosynthesis in liver is: N6-trimethyl-lysine leads to 3-hydryxy-N6-trimethyl-lysine leads to leads to 4-trimethylammoniobutyrate leads to carnitine. PMID:6772168

  12. 32 CFR 1627.2 - Registration of volunteers.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 6 2011-07-01 2011-07-01 false Registration of volunteers. 1627.2 Section 1627... VOLUNTEERS FOR INDUCTION § 1627.2 Registration of volunteers. (a) If a person who is required to be registered but who has failed to register volunteers for induction, he shall be registered. (b) In...

  13. 32 CFR 1627.2 - Registration of volunteers.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Registration of volunteers. 1627.2 Section 1627... VOLUNTEERS FOR INDUCTION § 1627.2 Registration of volunteers. (a) If a person who is required to be registered but who has failed to register volunteers for induction, he shall be registered. (b) In...

  14. 32 CFR 1627.2 - Registration of volunteers.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 6 2012-07-01 2012-07-01 false Registration of volunteers. 1627.2 Section 1627... VOLUNTEERS FOR INDUCTION § 1627.2 Registration of volunteers. (a) If a person who is required to be registered but who has failed to register volunteers for induction, he shall be registered. (b) In...

  15. 32 CFR 1627.2 - Registration of volunteers.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 6 2014-07-01 2014-07-01 false Registration of volunteers. 1627.2 Section 1627... VOLUNTEERS FOR INDUCTION § 1627.2 Registration of volunteers. (a) If a person who is required to be registered but who has failed to register volunteers for induction, he shall be registered. (b) In...

  16. 32 CFR 1627.2 - Registration of volunteers.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 6 2013-07-01 2013-07-01 false Registration of volunteers. 1627.2 Section 1627... VOLUNTEERS FOR INDUCTION § 1627.2 Registration of volunteers. (a) If a person who is required to be registered but who has failed to register volunteers for induction, he shall be registered. (b) In...

  17. 32 CFR 1651.4 - Review by district appeal board.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... personal appearance and such summary shall be placed in the registrant's file. (n) A district appeal board... registrant's file; and (2) Oral statements by the registrant during the registrant's personal appearance; and... compensated employee authorized to perform the administrative duties of the board shall review the file to...

  18. 26 CFR 6a.6652(g)-1 - Failure to make return or furnish statement required under section 6039C.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... required under section 6039C. 6a.6652(g)-1 Section 6a.6652(g)-1 Internal Revenue INTERNAL REVENUE SERVICE... OMNIBUS RECONCILIATION ACT OF 1980 § 6a.6652(g)-1 Failure to make return or furnish statement required... limitation under § 6a.6652(g)-1(b)(3) with respect to failure to meet the requirements of section 6039C(c), U...

  19. 26 CFR 6a.6652(g)-1 - Failure to make return or furnish statement required under section 6039C.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... required under section 6039C. 6a.6652(g)-1 Section 6a.6652(g)-1 Internal Revenue INTERNAL REVENUE SERVICE... OMNIBUS RECONCILIATION ACT OF 1980 § 6a.6652(g)-1 Failure to make return or furnish statement required... limitation under § 6a.6652(g)-1(b)(3) with respect to failure to meet the requirements of section 6039C(c), U...

  20. 26 CFR 6a.6652(g)-1 - Failure to make return or furnish statement required under section 6039C.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... required under section 6039C. 6a.6652(g)-1 Section 6a.6652(g)-1 Internal Revenue INTERNAL REVENUE SERVICE... OMNIBUS RECONCILIATION ACT OF 1980 § 6a.6652(g)-1 Failure to make return or furnish statement required... limitation under § 6a.6652(g)-1(b)(3) with respect to failure to meet the requirements of section 6039C(c), U...

  1. 26 CFR 6a.6652(g)-1 - Failure to make return or furnish statement required under section 6039C.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... required under section 6039C. 6a.6652(g)-1 Section 6a.6652(g)-1 Internal Revenue INTERNAL REVENUE SERVICE... OMNIBUS RECONCILIATION ACT OF 1980 § 6a.6652(g)-1 Failure to make return or furnish statement required... limitation under § 6a.6652(g)-1(b)(3) with respect to failure to meet the requirements of section 6039C(c), U...

  2. 26 CFR 6a.6652(g)-1 - Failure to make return or furnish statement required under section 6039C.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... required under section 6039C. 6a.6652(g)-1 Section 6a.6652(g)-1 Internal Revenue INTERNAL REVENUE SERVICE... OMNIBUS RECONCILIATION ACT OF 1980 § 6a.6652(g)-1 Failure to make return or furnish statement required... limitation under § 6a.6652(g)-1(b)(3) with respect to failure to meet the requirements of section 6039C(c), U...

  3. 17 CFR 240.15Ba2-6T - Temporary registration as a municipal advisor; required amendments; and withdrawal from temporary...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Temporary registration as a....15Ba2-6T Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) GENERAL RULES AND REGULATIONS, SECURITIES EXCHANGE ACT OF 1934 Rules and Regulations Under the Securities Exchange...

  4. 17 CFR 240.15Ba2-6T - Temporary registration as a municipal advisor; required amendments; and withdrawal from temporary...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 4 2014-04-01 2014-04-01 false Temporary registration as a....15Ba2-6T Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) GENERAL RULES AND REGULATIONS, SECURITIES EXCHANGE ACT OF 1934 Rules and Regulations Under the Securities Exchange...

  5. 17 CFR 240.15Ba2-6T - Temporary registration as a municipal advisor; required amendments; and withdrawal from temporary...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 3 2013-04-01 2013-04-01 false Temporary registration as a....15Ba2-6T Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) GENERAL RULES AND REGULATIONS, SECURITIES EXCHANGE ACT OF 1934 Rules and Regulations Under the Securities Exchange...

  6. 17 CFR 240.15Ba2-6T - Temporary registration as a municipal advisor; required amendments; and withdrawal from temporary...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 3 2012-04-01 2012-04-01 false Temporary registration as a....15Ba2-6T Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) GENERAL RULES AND REGULATIONS, SECURITIES EXCHANGE ACT OF 1934 Rules and Regulations Under the Securities Exchange...

  7. 17 CFR 210.3-16 - Financial statements of affiliates whose securities collateralize an issue registered or being...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 2 2012-04-01 2012-04-01 false Financial statements of affiliates whose securities collateralize an issue registered or being registered. 210.3-16 Section 210.3-16... aggregate principal amount, par value, or book value of the securities as carried by the registrant, or the...

  8. 17 CFR 210.3-16 - Financial statements of affiliates whose securities collateralize an issue registered or being...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 2 2013-04-01 2013-04-01 false Financial statements of affiliates whose securities collateralize an issue registered or being registered. 210.3-16 Section 210.3-16... aggregate principal amount, par value, or book value of the securities as carried by the registrant, or the...

  9. 76 FR 51430 - Roots Pharmaceuticals, Inc.; Revocation of Registration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-18

    ... Registration BR9610571, which authorizes it to dispense controlled substances as a retail pharmacy, on the ground that Registrant's state pharmacy and controlled substance licenses had expired on September 30... retail pharmacy, at the registered location of 12 W 100N, Suite 201B, American Fork, Utah. GX A...

  10. Unpacking the Logic of Mathematical Statements.

    ERIC Educational Resources Information Center

    Selden, John; Selden, Annie

    1995-01-01

    Investigated (n=61) undergraduates' ability to unpack informally written mathematical statements into the language of predicate calculus in an introduction to proofs and mathematical reasoning. Found that students were unable to construct proofs or validate them. Appendices are "A Sample Validation" and "Building a Statement Image." (MKR)

  11. Multibeam 3D Underwater SLAM with Probabilistic Registration.

    PubMed

    Palomer, Albert; Ridao, Pere; Ribas, David

    2016-04-20

    This paper describes a pose-based underwater 3D Simultaneous Localization and Mapping (SLAM) using a multibeam echosounder to produce high consistency underwater maps. The proposed algorithm compounds swath profiles of the seafloor with dead reckoning localization to build surface patches (i.e., point clouds). An Iterative Closest Point (ICP) with a probabilistic implementation is then used to register the point clouds, taking into account their uncertainties. The registration process is divided in two steps: (1) point-to-point association for coarse registration and (2) point-to-plane association for fine registration. The point clouds of the surfaces to be registered are sub-sampled in order to decrease both the computation time and also the potential of falling into local minima during the registration. In addition, a heuristic is used to decrease the complexity of the association step of the ICP from O(n2) to O(n) . The performance of the SLAM framework is tested using two real world datasets: First, a 2.5D bathymetric dataset obtained with the usual down-looking multibeam sonar configuration, and second, a full 3D underwater dataset acquired with a multibeam sonar mounted on a pan and tilt unit.

  12. 21 CFR 1301.35 - Certificate of registration; denial of registration.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... registration. (a) The Administrator shall issue a Certificate of Registration (DEA Form 223) to an applicant if... Federal Register. (c) The Certificate of Registration (DEA Form 223) shall contain the name, address, and...

  13. 21 CFR 1301.35 - Certificate of registration; denial of registration.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... registration. (a) The Administrator shall issue a Certificate of Registration (DEA Form 223) to an applicant if... Federal Register. (c) The Certificate of Registration (DEA Form 223) shall contain the name, address, and...

  14. 32 CFR 1624.4 - Selection and/or rescheduling of registrants for induction.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 6 2013-07-01 2013-07-01 false Selection and/or rescheduling of registrants for induction. 1624.4 Section 1624.4 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM INDUCTIONS § 1624.4 Selection and/or rescheduling of registrants for induction. A registrant in Class 1-A or a registrant...

  15. 32 CFR 1624.4 - Selection and/or rescheduling of registrants for induction.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Selection and/or rescheduling of registrants for induction. 1624.4 Section 1624.4 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM INDUCTIONS § 1624.4 Selection and/or rescheduling of registrants for induction. A registrant in Class 1-A or a registrant...

  16. 32 CFR 1624.4 - Selection and/or rescheduling of registrants for induction.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 6 2011-07-01 2011-07-01 false Selection and/or rescheduling of registrants for induction. 1624.4 Section 1624.4 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM INDUCTIONS § 1624.4 Selection and/or rescheduling of registrants for induction. A registrant in Class 1-A or a registrant...

  17. 32 CFR 1624.4 - Selection and/or rescheduling of registrants for induction.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 6 2014-07-01 2014-07-01 false Selection and/or rescheduling of registrants for induction. 1624.4 Section 1624.4 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM INDUCTIONS § 1624.4 Selection and/or rescheduling of registrants for induction. A registrant in Class 1-A or a registrant...

  18. 32 CFR 1624.4 - Selection and/or rescheduling of registrants for induction.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 6 2012-07-01 2012-07-01 false Selection and/or rescheduling of registrants for induction. 1624.4 Section 1624.4 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM INDUCTIONS § 1624.4 Selection and/or rescheduling of registrants for induction. A registrant in Class 1-A or a registrant...

  19. 21 CFR 1309.42 - Certificate of registration; denial of registration.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...; denial of registration. (a) The Administrator shall issue a Certificate of Registration (DEA Form 511) to..., shall hold a hearing on the application pursuant to § 1309.51. (b) The Certificate of Registration (DEA...

  20. 21 CFR 1309.42 - Certificate of registration; denial of registration.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...; denial of registration. (a) The Administrator shall issue a Certificate of Registration (DEA Form 511) to..., shall hold a hearing on the application pursuant to § 1309.51. (b) The Certificate of Registration (DEA...

  1. Development and evaluation of an articulated registration algorithm for human skeleton registration

    NASA Astrophysics Data System (ADS)

    Yip, Stephen; Perk, Timothy; Jeraj, Robert

    2014-03-01

    Accurate registration over multiple scans is necessary to assess treatment response of bone diseases (e.g. metastatic bone lesions). This study aimed to develop and evaluate an articulated registration algorithm for the whole-body skeleton registration in human patients. In articulated registration, whole-body skeletons are registered by auto-segmenting into individual bones using atlas-based segmentation, and then rigidly aligning them. Sixteen patients (weight = 80-117 kg, height = 168-191 cm) with advanced prostate cancer underwent the pre- and mid-treatment PET/CT scans over a course of cancer therapy. Skeletons were extracted from the CT images by thresholding (HU>150). Skeletons were registered using the articulated, rigid, and deformable registration algorithms to account for position and postural variability between scans. The inter-observers agreement in the atlas creation, the agreement between the manually and atlas-based segmented bones, and the registration performances of all three registration algorithms were all assessed using the Dice similarity index—DSIobserved, DSIatlas, and DSIregister. Hausdorff distance (dHausdorff) of the registered skeletons was also used for registration evaluation. Nearly negligible inter-observers variability was found in the bone atlases creation as the DSIobserver was 96 ± 2%. Atlas-based and manual segmented bones were in excellent agreement with DSIatlas of 90 ± 3%. Articulated (DSIregsiter = 75 ± 2%, dHausdorff = 0.37 ± 0.08 cm) and deformable registration algorithms (DSIregister = 77 ± 3%, dHausdorff = 0.34 ± 0.08 cm) considerably outperformed the rigid registration algorithm (DSIregsiter = 59 ± 9%, dHausdorff = 0.69 ± 0.20 cm) in the skeleton registration as the rigid registration algorithm failed to capture the skeleton flexibility in the joints. Despite superior skeleton registration performance, deformable registration algorithm failed to preserve the local rigidity of bones as over 60% of the

  2. 17 CFR 239.39 - Form F-9, for registration under the Securities Act of 1933 of certain investment grade debt or...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... under the Securities Act of 1933 of certain investment grade debt or investment grade preferred... Statements § 239.39 Form F-9, for registration under the Securities Act of 1933 of certain investment grade debt or investment grade preferred securities of certain Canadian issuers. (a) Form F-9 may be used for...

  3. 17 CFR 239.13 - Form S-3, for registration under the Securities Act of 1933 of securities of certain issuers...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 2 2013-04-01 2013-04-01 false Form S-3, for registration... statement that it has a reasonable belief that it would have been eligible to use this Form S-3 as of... securities, discloses the basis for such belief, and files a final prospectus for an offering pursuant to...

  4. 17 CFR 239.13 - Form S-3, for registration under the Securities Act of 1933 of securities of certain issuers...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 2 2012-04-01 2012-04-01 false Form S-3, for registration... statement that it has a reasonable belief that it would have been eligible to use this Form S-3 as of... securities, discloses the basis for such belief, and files a final prospectus for an offering pursuant to...

  5. 17 CFR 239.13 - Form S-3, for registration under the Securities Act of 1933 of securities of certain issuers...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 3 2014-04-01 2014-04-01 false Form S-3, for registration... statement that it has a reasonable belief that it would have been eligible to use this Form S-3 as of... securities, discloses the basis for such belief, and files a final prospectus for an offering pursuant to...

  6. 78 FR 14540 - Chlorpyrifos Registration Review; Preliminary Volatilization Assessment; Extension of Comment Period

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-06

    ... ENVIRONMENTAL PROTECTION AGENCY [EPA-HQ-OPP-2008-0850; FRL-9380-7] Chlorpyrifos Registration... Federal Register issue of February 6, 2013, concerning Chlorpyrifos Registration Review; Preliminary... volatilization assessment for the registration review of chlorpyrifos. EPA received requests from several...

  7. Central Contractor Registration Handbook (CCR)

    DTIC Science & Technology

    2002-03-01

    Assistance Center 888-227-2423 or 616-961-4725 Report Documentation Page Report Date 00/03/2002 Report Type N/A Dates Covered (from... to) - Title and......Work Unit Number Performing Organization Name(s) and Address(es) Central Contractor Registration Assistance Center (888-227-2423) or (616-961-4725

  8. 76 FR 4940 - Algirdas J. Krisciunas, M.D.; Revocation of Registration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-27

    ... substances and the visit. Id. at 5-6. On January 7, 2010, a Federal Grand Jury indicted Registrant. United..., 2010, a Federal Grand Jury issued a superseding indictment. United States v. Algirdas Krisciunas and... went to trial. On July 6, 2010, a jury found Registrant guilty on all six counts. U.S. v. Algirdas...

  9. 21 CFR 710.8 - Misbranding by reference to registration or to registration number.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... HUMAN SERVICES (CONTINUED) COSMETICS VOLUNTARY REGISTRATION OF COSMETIC PRODUCT ESTABLISHMENTS § 710.8 Misbranding by reference to registration or to registration number. Registration of a cosmetic product...

  10. 21 CFR 710.8 - Misbranding by reference to registration or to registration number.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... HUMAN SERVICES (CONTINUED) COSMETICS VOLUNTARY REGISTRATION OF COSMETIC PRODUCT ESTABLISHMENTS § 710.8 Misbranding by reference to registration or to registration number. Registration of a cosmetic product...

  11. 21 CFR 710.8 - Misbranding by reference to registration or to registration number.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... HUMAN SERVICES (CONTINUED) COSMETICS VOLUNTARY REGISTRATION OF COSMETIC PRODUCT ESTABLISHMENTS § 710.8 Misbranding by reference to registration or to registration number. Registration of a cosmetic product...

  12. 21 CFR 710.8 - Misbranding by reference to registration or to registration number.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... HUMAN SERVICES (CONTINUED) COSMETICS VOLUNTARY REGISTRATION OF COSMETIC PRODUCT ESTABLISHMENTS § 710.8 Misbranding by reference to registration or to registration number. Registration of a cosmetic product...

  13. 21 CFR 710.8 - Misbranding by reference to registration or to registration number.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... HUMAN SERVICES (CONTINUED) COSMETICS VOLUNTARY REGISTRATION OF COSMETIC PRODUCT ESTABLISHMENTS § 710.8 Misbranding by reference to registration or to registration number. Registration of a cosmetic product...

  14. 76 FR 54717 - Supervised Securities Holding Companies Registration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-02

    ... other financial statements submitted to the securities holding company's current consolidated supervisor... Y-9ES), The Supplement to the Consolidated Financial Statements for Bank Holding Companies (FR Y-9CS... Companies (FR Y-6), The Report of Foreign Banking Organizations (FR Y-7), The Consolidated Financial...

  15. 75 FR 41968 - Re-Registration and Renewal of Aircraft Registration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-20

    ... the use of the second or ``Pink Copy'' of the application for registration for a reasonable period of... under ``Pink Copy'' temporary authority at any time if an application for registration is made. Due to... reference to the ``pink copy'' of the Aircraft Registration Application. V. Miscellaneous Comments A. Re...

  16. 7 CFR 402.1 - General statement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 6 2011-01-01 2011-01-01 false General statement. 402.1 Section 402.1 Agriculture Regulations of the Department of Agriculture (Continued) FEDERAL CROP INSURANCE CORPORATION, DEPARTMENT OF AGRICULTURE CATASTROPHIC RISK PROTECTION ENDORSEMENT § 402.1 General statement. The Federal Crop Insurance Act...

  17. 7 CFR 510.1 - General statement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 6 2010-01-01 2010-01-01 false General statement. 510.1 Section 510.1 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL RESEARCH SERVICE, DEPARTMENT OF AGRICULTURE PUBLIC INFORMATION § 510.1 General statement. This part is issued in accordance with the...

  18. 7 CFR 402.1 - General statement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 6 2010-01-01 2010-01-01 false General statement. 402.1 Section 402.1 Agriculture Regulations of the Department of Agriculture (Continued) FEDERAL CROP INSURANCE CORPORATION, DEPARTMENT OF AGRICULTURE CATASTROPHIC RISK PROTECTION ENDORSEMENT § 402.1 General statement. The Federal Crop Insurance Act...

  19. Comparison of Online 6 Degree-of-Freedom Image Registration of Varian TrueBeam Cone-Beam CT and BrainLab ExacTrac X-Ray for Intracranial Radiosurgery.

    PubMed

    Li, Jun; Shi, Wenyin; Andrews, David; Werner-Wasik, Maria; Lu, Bo; Yu, Yan; Dicker, Adam; Liu, Haisong

    2017-06-01

    The study was aimed to compare online 6 degree-of-freedom image registrations of TrueBeam cone-beam computed tomography and BrainLab ExacTrac X-ray imaging systems for intracranial radiosurgery. Phantom and patient studies were performed on a Varian TrueBeam STx linear accelerator (version 2.5), which is integrated with a BrainLab ExacTrac imaging system (version 6.1.1). The phantom study was based on a Rando head phantom and was designed to evaluate isocenter location dependence of the image registrations. Ten isocenters at various locations representing clinical treatment sites were selected in the phantom. Cone-beam computed tomography and ExacTrac X-ray images were taken when the phantom was located at each isocenter. The patient study included 34 patients. Cone-beam computed tomography and ExacTrac X-ray images were taken at each patient's treatment position. The 6 degree-of-freedom image registrations were performed on cone-beam computed tomography and ExacTrac, and residual errors calculated from cone-beam computed tomography and ExacTrac were compared. In the phantom study, the average residual error differences (absolute values) between cone-beam computed tomography and ExacTrac image registrations were 0.17 ± 0.11 mm, 0.36 ± 0.20 mm, and 0.25 ± 0.11 mm in the vertical, longitudinal, and lateral directions, respectively. The average residual error differences in the rotation, roll, and pitch were 0.34° ± 0.08°, 0.13° ± 0.09°, and 0.12° ± 0.10°, respectively. In the patient study, the average residual error differences in the vertical, longitudinal, and lateral directions were 0.20 ± 0.16 mm, 0.30 ± 0.18 mm, 0.21 ± 0.18 mm, respectively. The average residual error differences in the rotation, roll, and pitch were 0.40°± 0.16°, 0.17° ± 0.13°, and 0.20° ± 0.14°, respectively. Overall, the average residual error differences were <0.4 mm in the translational directions and <0.5° in the rotational directions. ExacTrac X-ray image

  20. Undergraduate Cross Registration.

    ERIC Educational Resources Information Center

    Grupe, Fritz H.

    This report discusses various aspects of undergraduate cross-registration procedures, including the dimensions, values, roles and functions, basic assumptions, and facilitating and encouragment of cross-registration. Dimensions of cross-registration encompass financial exchange, eligibility, program limitations, type of grade and credit; extent of…

  1. 40 CFR 156.206 - General statements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... (i.e., an organophosphorus ester that inhibits cholinesterase) or an N-methyl carbamate (i.e., an N-methyl carbamic acid ester that inhibits cholinesterase), the label shall so state. The statement shall...

  2. 40 CFR 156.206 - General statements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... (i.e., an organophosphorus ester that inhibits cholinesterase) or an N-methyl carbamate (i.e., an N-methyl carbamic acid ester that inhibits cholinesterase), the label shall so state. The statement shall...

  3. 40 CFR 156.206 - General statements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... (i.e., an organophosphorus ester that inhibits cholinesterase) or an N-methyl carbamate (i.e., an N-methyl carbamic acid ester that inhibits cholinesterase), the label shall so state. The statement shall...

  4. 40 CFR 156.206 - General statements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... (i.e., an organophosphorus ester that inhibits cholinesterase) or an N-methyl carbamate (i.e., an N-methyl carbamic acid ester that inhibits cholinesterase), the label shall so state. The statement shall...

  5. PRN 94-7: Label Improvement Program for the Revision of Use Directions for Commensal Rodenticides and Statement of the Agency's Policies on the Use of Rodenticide Bait Stations

    EPA Pesticide Factsheets

    This Notice requires registrants of certain pesticide products claimed to control commensal rodents and registered under FIFRA to revise the labeling of such products to bear certain statements concerning tamper-resistant bait stations.

  6. Registration of Space Objects

    NASA Astrophysics Data System (ADS)

    Schmidt-Tedd, Bernhard

    2017-07-01

    Space objects are subject to registration in order to allocate "jurisdiction and control" over those objects in the sovereign-free environment of outer space. This approach is similar to the registration of ships in view of the high sea and for aircrafts with respect to the international airspace. Registration is one of the basic principles of space law, starting with UN General Assembly Resolution 1721 B (XVI) of December 20, 1961, followed by Resolution 1962 (XVIII) of December 13, 1963, then formulated in Article VIII of the Outer Space Treaty of 1967 and as specified in the Registration Convention of 1975. Registration of space objects can be seen today as a principle of customary international law, relevant for each spacefaring state. Registration is divided into a national and an international level. The State Party establishes a national registry for its space objects, and those registrations have to be communicated via diplomatic channel to the UN Register of space objects. This UN Register is handled by the UN Office for Outer Space Affairs (UNOOSA) and is an open source of information for space objects worldwide. Registration is linked to the so-called launching state of the relevant space object. There might be more than one launching state for the specific launch event, but only one state actor can register a specific space object. The state of registry gains "jurisdiction and control" over the space object and therefore no double registration is permissible. Based on the established UN Space Law, registration practice was subject to some adaptions due to technical developments and legal challenges. After the privatization of the major international satellite organizations, a number of non-registrations had to be faced. The state actors reacted with the UN Registration Practice Resolution of 2007 as elaborated in the Legal Subcommittee of UNCOPUOS, the Committee for the Peaceful Use of Outer Space. In this context an UNOOSA Registration Information

  7. 40 CFR 124.61 - Final environmental impact statement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 21 2010-07-01 2010-07-01 false Final environmental impact statement... environmental impact statement. No final NPDES permit for a new source shall be issued until at least 30 days after the date of issuance of a final environmental impact statement if one is required under 40 CFR 6...

  8. Multi-system verification of registrations for image-guided radiotherapy in clinical trials.

    PubMed

    Cui, Yunfeng; Galvin, James M; Straube, William L; Bosch, Walter R; Purdy, James A; Li, X Allen; Xiao, Ying

    2011-09-01

    To provide quantitative information on the image registration differences from multiple systems for image-guided radiotherapy (IGRT) credentialing and margin reduction in clinical trials. Images and IGRT shift results from three different treatment systems (Tomotherapy Hi-Art, Elekta Synergy, Varian Trilogy) have been sent from various institutions to the Image-Guided Therapy QA Center (ITC) for evaluation for the Radiation Therapy Oncology Group (RTOG) trials. Nine patient datasets (five head-and-neck and four prostate) were included in the comparison, with each patient having 1-4 daily individual IGRT studies. In all cases, daily shifts were re-calculated by re-registration of the planning CT with the daily IGRT data using three independent software systems (MIMvista, FocalSim, VelocityAI). Automatic fusion was used in all calculations. The results were compared with those submitted from institutions. Similar regions of interest (ROIs) and same initial positions were used in registrations for inter-system comparison. Different slice spacings for CBCT sampling and different ROIs for registration were used in some cases to observe the variation of registration due to these factors. For the 54 comparisons with head-and-neck datasets, the absolute values of differences of the registration results between different systems were 2.6±2.1 mm (mean±SD; range 0.1-8.6 mm, left-right [LR]), 1.7±1.3 mm (0.0-4.9 mm, superior-inferior [SI]), and 1.8±1.1 mm (0.1-4.0 mm, anterior-posterior [AP]). For the 66 comparisons in prostate cases, the differences were 1.1±1.0 mm (0.0-4.6 mm, LR), 2.1±1.7 mm (0.0-6.6 mm, SI), and 2.0±1.8 mm (0.1-6.9 mm, AP). The differences caused by the slice spacing variation were relatively small, and the different ROI selections in FocalSim and MIMvista also had limited impact. The extent of differences was reported when different systems were used for image registration. Careful examination and quality assurance of the image registration process

  9. 77 FR 46774 - Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-06

    ..., DC 20549-0213. Extension: Form N-5, SEC File No. 270-172, OMB Control No. 3235-0169. Notice is hereby... Management and Budget for extension and approval. Form N-5 (17 CFR 239.24 and 274.5)--Registration Statement... the Investment Company Act of 1940 (15 U.S.C. 80a-1 et seq.) Form N-5 is the integrated registration...

  10. Volumetric Image Guidance Using Carina vs Spine as Registration Landmarks for Conventionally Fractionated Lung Radiotherapy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lavoie, Caroline; Higgins, Jane; Bissonnette, Jean-Pierre

    2012-12-01

    Purpose: To compare the relative accuracy of 2 image guided radiation therapy methods using carina vs spine as landmarks and then to identify which landmark is superior relative to tumor coverage. Methods and Materials: For 98 lung patients, 2596 daily image-guidance cone-beam computed tomography scans were analyzed. Tattoos were used for initial patient alignment; then, spine and carina registrations were performed independently. A separate analysis assessed the adequacy of gross tumor volume, internal target volume, and planning target volume coverage on cone-beam computed tomography using the initial, middle, and final fractions of radiation therapy. Coverage was recorded for primary tumormore » (T), nodes (N), and combined target (T+N). Three scenarios were compared: tattoos alignment, spine registration, and carina registration. Results: Spine and carina registrations identified setup errors {>=}5 mm in 35% and 46% of fractions, respectively. The mean vector difference between spine and carina matching had a magnitude of 3.3 mm. Spine and carina improved combined target coverage, compared with tattoos, in 50% and 34% (spine) to 54% and 46% (carina) of the first and final fractions, respectively. Carina matching showed greater combined target coverage in 17% and 23% of fractions for the first and final fractions, respectively; with spine matching, this was only observed in 4% (first) and 6% (final) of fractions. Carina matching provided superior nodes coverage at the end of radiation compared with spine matching (P=.0006), without compromising primary tumor coverage. Conclusion: Frequent patient setup errors occur in locally advanced lung cancer patients. Spine and carina registrations improved combined target coverage throughout the treatment course, but carina matching provided superior combined target coverage.« less

  11. 16 CFR 1130.8 - Requirements for Web site registration or alternative e-mail registration.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 2 2012-01-01 2012-01-01 false Requirements for Web site registration or... PRODUCTS § 1130.8 Requirements for Web site registration or alternative e-mail registration. (a) Link to registration page. The manufacturer's Web site, or other Web site established for the purpose of registration...

  12. 16 CFR 1130.8 - Requirements for Web site registration or alternative e-mail registration.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 2 2011-01-01 2011-01-01 false Requirements for Web site registration or... PRODUCTS § 1130.8 Requirements for Web site registration or alternative e-mail registration. (a) Link to registration page. The manufacturer's Web site, or other Web site established for the purpose of registration...

  13. 16 CFR 1130.7 - Requirements for Web site registration or alternative e-mail registration.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 16 Commercial Practices 2 2014-01-01 2014-01-01 false Requirements for Web site registration or... PRODUCTS § 1130.7 Requirements for Web site registration or alternative e-mail registration. (a) Link to registration page. The manufacturer's Web site, or other Web site established for the purpose of registration...

  14. 17 CFR 210.6-09 - Statements of changes in net assets.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., INVESTMENT ADVISERS ACT OF 1940, AND ENERGY POLICY AND CONSERVATION ACT OF 1975 Registered Investment... persons to whom this article is applicable shall comply with the following provisions: Statements of...

  15. 17 CFR 210.6-09 - Statements of changes in net assets.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., INVESTMENT ADVISERS ACT OF 1940, AND ENERGY POLICY AND CONSERVATION ACT OF 1975 Registered Investment... persons to whom this article is applicable shall comply with the following provisions: Statements of...

  16. Lung texture in serial thoracic CT scans: Assessment of change introduced by image registration1

    PubMed Central

    Cunliffe, Alexandra R.; Al-Hallaq, Hania A.; Labby, Zacariah E.; Pelizzari, Charles A.; Straus, Christopher; Sensakovic, William F.; Ludwig, Michelle; Armato, Samuel G.

    2012-01-01

    Purpose: The aim of this study was to quantify the effect of four image registration methods on lung texture features extracted from serial computed tomography (CT) scans obtained from healthy human subjects. Methods: Two chest CT scans acquired at different time points were collected retrospectively for each of 27 patients. Following automated lung segmentation, each follow-up CT scan was registered to the baseline scan using four algorithms: (1) rigid, (2) affine, (3) B-splines deformable, and (4) demons deformable. The registration accuracy for each scan pair was evaluated by measuring the Euclidean distance between 150 identified landmarks. On average, 1432 spatially matched 32 × 32-pixel region-of-interest (ROI) pairs were automatically extracted from each scan pair. First-order, fractal, Fourier, Laws’ filter, and gray-level co-occurrence matrix texture features were calculated in each ROI, for a total of 140 features. Agreement between baseline and follow-up scan ROI feature values was assessed by Bland–Altman analysis for each feature; the range spanned by the 95% limits of agreement of feature value differences was calculated and normalized by the average feature value to obtain the normalized range of agreement (nRoA). Features with small nRoA were considered “registration-stable.” The normalized bias for each feature was calculated from the feature value differences between baseline and follow-up scans averaged across all ROIs in every patient. Because patients had “normal” chest CT scans, minimal change in texture feature values between scan pairs was anticipated, with the expectation of small bias and narrow limits of agreement. Results: Registration with demons reduced the Euclidean distance between landmarks such that only 9% of landmarks were separated by ≥1 mm, compared with rigid (98%), affine (95%), and B-splines (90%). Ninety-nine of the 140 (71%) features analyzed yielded nRoA > 50% for all registration methods, indicating that

  17. 17 CFR 210.6A-03 - Statements of financial condition.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... EXCHANGE ACT OF 1934, PUBLIC UTILITY HOLDING COMPANY ACT OF 1935, INVESTMENT COMPANY ACT OF 1940, INVESTMENT ADVISERS ACT OF 1940, AND ENERGY POLICY AND CONSERVATION ACT OF 1975 Employee Stock Purchase... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Statements of financial...

  18. Can the UK's birth registration system better serve the interests of those born following collaborative assisted reproduction?

    PubMed

    Crawshaw, Marilyn A; Blyth, Eric D; Feast, Julia

    2017-06-01

    Current birth registration systems fail to serve adequately the interests of those born as a result of gamete and embryo donation and surrogacy. In the UK, changes to the birth registration system have been piecemeal, reactive and situation-specific and no information is recorded about gamete donors. Birth registration has thereby become a statement of legal parentage and citizenship only, without debate as to whether it should serve any wider functions. This sits uneasily with the increasingly accepted human right to know one's genetic and gestational as well as legal parents, and the duty of the State to facilitate that right. This commentary sets out one possible model for reform to better ensure that those affected become aware of, and/or have access to, knowledge about their origins and that such information is stored and released effectively without compromising individual privacy. Among other features, our proposal links the birth registration system and the information stored in the Human Fertilization and Embryology Authority's Register of Information, although further work than we have been able to undertake here is necessary to ensure a better fit where cross-border treatment services or informal arrangements have been involved. The time for debate and reform is well overdue.

  19. A DFT investigation on geometry and chemical bonding of isoelectronic Si8N6V-, Si8N6Cr, and Si8N6Mn+ clusters

    NASA Astrophysics Data System (ADS)

    Tam, Nguyen Minh; Pham, Hung Tan; Cuong, Ngo Tuan; Tung, Nguyen Thanh

    2017-10-01

    The geometric feature and chemical bonding of isoelectronic systems Si8N6Mq (M = V, Cr, Mn and q = -1, 0, 1, respectively) are investigated by means of density-functional-theory calculations. The encapsulated form is found for all ground-state structures, where the metal atom locates at the central site of the hollow Si8N6 cage. The Si8N6 cage is established by adding two Si atoms to a distorted Si6N6 prism, which is a combination of Si4N2 and Si2N4 strings. Chemical bonding of Si8N6Mq systems is explored by using the electron localization indicator and theory of atom in molecule, revealing the vital role of metal center in stabilizing the clusters.

  20. 46 CFR Exhibit 1 to Part 530 - Service Contract Registration [Form FMC-83

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    .... Address of Home Office. The complete street address should be shown in addition to the post office box.... Show the firm name (if different from the registrant), street address and post office box (if... 6. Registrant Type. Indicate the type of organization. A registrant cannot be more than one type...

  1. 46 CFR Exhibit 1 to Part 530 - Service Contract Registration [Form FMC-83

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    .... Address of Home Office. The complete street address should be shown in addition to the post office box.... Show the firm name (if different from the registrant), street address and post office box (if... 6. Registrant Type. Indicate the type of organization. A registrant cannot be more than one type...

  2. NOTE: Optimization of megavoltage CT scan registration settings for thoracic cases on helical tomotherapy

    NASA Astrophysics Data System (ADS)

    Woodford, Curtis; Yartsev, Slav; Van Dyk, Jake

    2007-08-01

    This study aims to investigate the settings that provide optimum registration accuracy when registering megavoltage CT (MVCT) studies acquired on tomotherapy with planning kilovoltage CT (kVCT) studies of patients with lung cancer. For each experiment, the systematic difference between the actual and planned positions of the thorax phantom was determined by setting the phantom up at the planning isocenter, generating and registering an MVCT study. The phantom was translated by 5 or 10 mm, MVCT scanned, and registration was performed again. A root-mean-square equation that calculated the residual error of the registration based on the known shift and systematic difference was used to assess the accuracy of the registration process. The phantom study results for 18 combinations of different MVCT/kVCT registration options are presented and compared to clinical registration data from 17 lung cancer patients. MVCT studies acquired with coarse (6 mm), normal (4 mm) and fine (2 mm) slice spacings could all be registered with similar residual errors. No specific combination of resolution and fusion selection technique resulted in a lower residual error. A scan length of 6 cm with any slice spacing registered with the full image fusion selection technique and fine resolution will result in a low residual error most of the time. On average, large corrections made manually by clinicians to the automatic registration values are infrequent. Small manual corrections within the residual error averages of the registration process occur, but their impact on the average patient position is small. Registrations using the full image fusion selection technique and fine resolution of 6 cm MVCT scans with coarse slices have a low residual error, and this strategy can be clinically used for lung cancer patients treated on tomotherapy. Automatic registration values are accurate on average, and a quick verification on a sagittal MVCT slice should be enough to detect registration outliers.

  3. 12 CFR 563d.3b-6 - Liability for certain statements by savings associations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... the time such statements are made or reaffirmed, either: (A) The issuer is subject to the reporting... issuer is not subject to the reporting requirements of section 13(a) or 15(d) of the Act, the statements... under the Investment Company Act of 1940; (2) Information (i) relating to the effects of changing prices...

  4. 12 CFR 563d.3b-6 - Liability for certain statements by savings associations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... the time such statements are made or reaffirmed, either: (A) The issuer is subject to the reporting... issuer is not subject to the reporting requirements of section 13(a) or 15(d) of the Act, the statements... under the Investment Company Act of 1940; (2) Information (i) relating to the effects of changing prices...

  5. Registration performance on EUV masks using high-resolution registration metrology

    NASA Astrophysics Data System (ADS)

    Steinert, Steffen; Solowan, Hans-Michael; Park, Jinback; Han, Hakseung; Beyer, Dirk; Scherübl, Thomas

    2016-10-01

    Next-generation lithography based on EUV continues to move forward to high-volume manufacturing. Given the technical challenges and the throughput concerns a hybrid approach with 193 nm immersion lithography is expected, at least in the initial state. Due to the increasing complexity at smaller nodes a multitude of different masks, both DUV (193 nm) and EUV (13.5 nm) reticles, will then be required in the lithography process-flow. The individual registration of each mask and the resulting overlay error are of crucial importance in order to ensure proper functionality of the chips. While registration and overlay metrology on DUV masks has been the standard for decades, this has yet to be demonstrated on EUV masks. Past generations of mask registration tools were not necessarily limited in their tool stability, but in their resolution capabilities. The scope of this work is an image placement investigation of high-end EUV masks together with a registration and resolution performance qualification. For this we employ a new generation registration metrology system embedded in a production environment for full-spec EUV masks. This paper presents excellent registration performance not only on standard overlay markers but also on more sophisticated e-beam calibration patterns.

  6. 75 FR 52859 - Re-Registration and Renewal of Aircraft Registration; OMB Approval of Information Collection

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-30

    ... Aircraft Registration; OMB Approval of Information Collection AGENCY: Federal Aviation Administration, DOT... final rule, ``Re-Registration and Renewal of Aircraft Registration,'' which was published on July 20..., the FAA published the final rule, ``Re-Registration and Renewal of Aircraft Registration'' (75 FR...

  7. 32 CFR 989.16 - Environmental impact statement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Environmental impact statement. 989.16 Section... PROTECTION ENVIRONMENTAL IMPACT ANALYSIS PROCESS (EIAP) § 989.16 Environmental impact statement. (a) Certain classes of environmental impacts normally require preparation of an EIS (40 CFR 1501.4). These include...

  8. 75 FR 58292 - Re-Registration and Renewal of Aircraft Registration; OMB Approval of Information Collection...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-24

    ...-0188; Amdt. No. 47-29A] RIN 2120-AI89 Re-Registration and Renewal of Aircraft Registration; OMB... contained in the ``Re-Registration and Renewal of Aircraft Registration'' final rule. The final rule was... Renewal of Aircraft Registration'' (75 FR 41968). The final rule contained information collection...

  9. 28 CFR 12.3 - Prior registration with the Foreign Agents Registration Unit.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 1 2013-07-01 2013-07-01 false Prior registration with the Foreign Agents Registration Unit. 12.3 Section 12.3 Judicial Administration DEPARTMENT OF JUSTICE REGISTRATION OF CERTAIN PERSONS HAVING KNOWLEDGE OF FOREIGN ESPIONAGE, COUNTERESPIONAGE, OR SABOTAGE MATTERS UNDER THE ACT...

  10. 28 CFR 12.3 - Prior registration with the Foreign Agents Registration Unit.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 1 2014-07-01 2014-07-01 false Prior registration with the Foreign Agents Registration Unit. 12.3 Section 12.3 Judicial Administration DEPARTMENT OF JUSTICE REGISTRATION OF CERTAIN PERSONS HAVING KNOWLEDGE OF FOREIGN ESPIONAGE, COUNTERESPIONAGE, OR SABOTAGE MATTERS UNDER THE ACT...

  11. 28 CFR 12.3 - Prior registration with the Foreign Agents Registration Unit.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Prior registration with the Foreign Agents Registration Unit. 12.3 Section 12.3 Judicial Administration DEPARTMENT OF JUSTICE REGISTRATION OF CERTAIN PERSONS HAVING KNOWLEDGE OF FOREIGN ESPIONAGE, COUNTERESPIONAGE, OR SABOTAGE MATTERS UNDER THE ACT...

  12. 28 CFR 12.3 - Prior registration with the Foreign Agents Registration Unit.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 1 2011-07-01 2011-07-01 false Prior registration with the Foreign Agents Registration Unit. 12.3 Section 12.3 Judicial Administration DEPARTMENT OF JUSTICE REGISTRATION OF CERTAIN PERSONS HAVING KNOWLEDGE OF FOREIGN ESPIONAGE, COUNTERESPIONAGE, OR SABOTAGE MATTERS UNDER THE ACT...

  13. 28 CFR 12.3 - Prior registration with the Foreign Agents Registration Unit.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 1 2012-07-01 2012-07-01 false Prior registration with the Foreign Agents Registration Unit. 12.3 Section 12.3 Judicial Administration DEPARTMENT OF JUSTICE REGISTRATION OF CERTAIN PERSONS HAVING KNOWLEDGE OF FOREIGN ESPIONAGE, COUNTERESPIONAGE, OR SABOTAGE MATTERS UNDER THE ACT...

  14. Lactobacillus johnsonii N6.2 Modulates the Host Immune Responses: A Double-Blind, Randomized Trial in Healthy Adults

    PubMed Central

    Marcial, Guillermo E.; Ford, Amanda L.; Haller, Michael J.; Gezan, Salvador A.; Harrison, Natalie A.; Cai, Dan; Meyer, Julie L.; Perry, Daniel J.; Atkinson, Mark A.; Wasserfall, Clive H.; Garrett, Timothy; Gonzalez, Claudio F.; Brusko, Todd M.; Dahl, Wendy J.; Lorca, Graciela L.

    2017-01-01

    Lactobacillus johnsonii N6.2 mitigates the onset of type 1 diabetes (T1D) in biobreeding diabetes-prone rats, in part, through changes in kynurenine:tryptophan (K:T) ratios. The goal of this pilot study was to determine the safety, tolerance, and general immunological response of L. johnsonii N6.2 in healthy subjects. A double-blind, randomized clinical trial in 42 healthy individuals with no known risk factors for T1D was undertaken to evaluate subject responses to the consumption of L. johnsonii N6.2. Participants received 1 capsule/day containing 108 colony-forming units of L. johnsonii N6.2 or placebo for 8 weeks. Comprehensive metabolic panel (CMP), leukocyte subpopulations by complete blood count (CBC) and flow cytometry, serum cytokines, and relevant metabolites in the indoleamine-2,3-dioxygenase pathway were assessed. L. johnsonii N6.2 survival and intestinal microbiota was analyzed. Daily and weekly questionnaires were assessed for potential effects of probiotic treatment on general wellness. The administration of L. johnsonii N6.2 did not modify the CMP or CBC of participants suggesting general safety. In fact, L. johnsonii N6.2 administration significantly decreased the occurrence of abdominal pain, indigestion, and cephalic syndromes. As predicted, increased serum tryptophan levels increased resulting in a decreased K:T ratio was observed in the L. johnsonii N6.2 group. Interestingly, immunophenotyping assays revealed that monocytes and natural killer cell numbers were increased significantly after washout (12 weeks). Moreover, an increase of circulating effector Th1 cells (CD45RO+CD183+CD196−) and cytotoxic CD8+ T cells subset was observed in the L. johnsonii N6.2 group. Consumption of L. johnsonii N6.2 is well tolerated in adult control subjects, demonstrates systemic impacts on innate and adaptive immune populations, and results in a decreased K:T ratio. These data provide support for the safety and feasibility of using L. johnsonii N6.2 in

  15. Improvement of registration accuracy in accelerated partial breast irradiation using the point-based rigid-body registration algorithm for patients with implanted fiducial markers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Inoue, Minoru; Yoshimura, Michio, E-mail: myossy@kuhp.kyoto-u.ac.jp; Sato, Sayaka

    2015-04-15

    Purpose: To investigate image-registration errors when using fiducial markers with a manual method and the point-based rigid-body registration (PRBR) algorithm in accelerated partial breast irradiation (APBI) patients, with accompanying fiducial deviations. Methods: Twenty-two consecutive patients were enrolled in a prospective trial examining 10-fraction APBI. Titanium clips were implanted intraoperatively around the seroma in all patients. For image-registration, the positions of the clips in daily kV x-ray images were matched to those in the planning digitally reconstructed radiographs. Fiducial and gravity registration errors (FREs and GREs, respectively), representing resulting misalignments of the edge and center of the target, respectively, were comparedmore » between the manual and algorithm-based methods. Results: In total, 218 fractions were evaluated. Although the mean FRE/GRE values for the manual and algorithm-based methods were within 3 mm (2.3/1.7 and 1.3/0.4 mm, respectively), the percentages of fractions where FRE/GRE exceeded 3 mm using the manual and algorithm-based methods were 18.8%/7.3% and 0%/0%, respectively. Manual registration resulted in 18.6% of patients with fractions of FRE/GRE exceeding 5 mm. The patients with larger clip deviation had significantly more fractions showing large FRE/GRE using manual registration. Conclusions: For image-registration using fiducial markers in APBI, the manual registration results in more fractions with considerable registration error due to loss of fiducial objectivity resulting from their deviation. The authors recommend the PRBR algorithm as a safe and effective strategy for accurate, image-guided registration and PTV margin reduction.« less

  16. Robust non-rigid registration algorithm based on local affine registration

    NASA Astrophysics Data System (ADS)

    Wu, Liyang; Xiong, Lei; Du, Shaoyi; Bi, Duyan; Fang, Ting; Liu, Kun; Wu, Dongpeng

    2018-04-01

    Aiming at the problem that the traditional point set non-rigid registration algorithm has low precision and slow convergence speed for complex local deformation data, this paper proposes a robust non-rigid registration algorithm based on local affine registration. The algorithm uses a hierarchical iterative method to complete the point set non-rigid registration from coarse to fine. In each iteration, the sub data point sets and sub model point sets are divided and the shape control points of each sub point set are updated. Then we use the control point guided affine ICP algorithm to solve the local affine transformation between the corresponding sub point sets. Next, the local affine transformation obtained by the previous step is used to update the sub data point sets and their shape control point sets. When the algorithm reaches the maximum iteration layer K, the loop ends and outputs the updated sub data point sets. Experimental results demonstrate that the accuracy and convergence of our algorithm are greatly improved compared with the traditional point set non-rigid registration algorithms.

  17. Plagiarism in Personal Statements of Anesthesiology Residency Applicants.

    PubMed

    Parks, Lance J; Sizemore, Daniel C; Johnstone, Robert E

    2016-02-15

    Plagiarism by residency applicants in their personal statements, as well as sites that sell personal statements, have been described, and led in 2011 to advice to avoid plagiarism and the caution that plagiarism detection software was available. We screened personal statements of 467 anesthesiology residency applicants from 2013-2014 using Viper Plagiarism Scanner software, and studied them for plagiarism. After quotes and commonly used phrases were removed, 82 statements contained unoriginal content of 8 or more consecutive words. After the study, 13.6% of personal statements from non-United States medical school graduates, and 4.0% from United States medical school graduates, contained plagiarized material, a significant difference. Plagiarized content ranged up to 58%. Plagiarism continues to occur in anesthesiology residency personal statements, with a higher incidence among graduates of non-United States medical schools.

  18. Demons deformable registration for CBCT-guided procedures in the head and neck: convergence and accuracy.

    PubMed

    Nithiananthan, S; Brock, K K; Daly, M J; Chan, H; Irish, J C; Siewerdsen, J H

    2009-10-01

    The accuracy and convergence behavior of a variant of the Demons deformable registration algorithm were investigated for use in cone-beam CT (CBCT)-guided procedures of the head and neck. Online use of deformable registration for guidance of therapeutic procedures such as image-guided surgery or radiation therapy places trade-offs on accuracy and computational expense. This work describes a convergence criterion for Demons registration developed to balance these demands; the accuracy of a multiscale Demons implementation using this convergence criterion is quantified in CBCT images of the head and neck. Using an open-source "symmetric" Demons registration algorithm, a convergence criterion based on the change in the deformation field between iterations was developed to advance among multiple levels of a multiscale image pyramid in a manner that optimized accuracy and computation time. The convergence criterion was optimized in cadaver studies involving CBCT images acquired using a surgical C-arm prototype modified for 3D intraoperative imaging. CBCT-to-CBCT registration was performed and accuracy was quantified in terms of the normalized cross-correlation (NCC) and target registration error (TRE). The accuracy and robustness of the algorithm were then tested in clinical CBCT images of ten patients undergoing radiation therapy of the head and neck. The cadaver model allowed optimization of the convergence factor and initial measurements of registration accuracy: Demons registration exhibited TRE=(0.8+/-0.3) mm and NCC =0.99 in the cadaveric head compared to TRE=(2.6+/-1.0) mm and NCC=0.93 with rigid registration. Similarly for the patient data, Demons registration gave mean TRE=(1.6+/-0.9) mm compared to rigid registration TRE=(3.6+/-1.9) mm, suggesting registration accuracy at or near the voxel size of the patient images (1 x 1 x 2 mm3). The multiscale implementation based on optimal convergence criteria completed registration in 52 s for the cadaveric head and in

  19. 16 CFR 1130.8 - Requirements for Web site registration or alternative e-mail registration.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Requirements for Web site registration or... PRODUCTS (Eff. June 28, 2010) § 1130.8 Requirements for Web site registration or alternative e-mail registration. (a) Link to registration page. The manufacturer's Web site, or other Web site established for the...

  20. High School Voter Registration.

    ERIC Educational Resources Information Center

    Institute for Political/Legal Education, Sewell, NJ.

    Methods for conducting peer voter registration of high school students cover establishing a permanent voter registration committee and identifying and registering eligible students. The permanent voter registration committee, made up of student body representatives, class representatives, and selected teachers, guarantees comprehensive…

  1. 17 CFR 274.303 - Form N-27I-2, notice of withdrawal right and statement of charges for variable life insurance...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... variable life insurance contractholders required pursuant to Rule 6e-2 (§ 270.6e-2 of this chapter). [41 FR... withdrawal right and statement of charges for variable life insurance contractholders required pursuant to Rule 6e-2 (§ 270.6e-2 of this chapter). 274.303 Section 274.303 Commodity and Securities Exchanges...

  2. 78 FR 64016 - Importer of Controlled Substances, Notice of Registration, Boehringer Ingelheim Chemicals

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-25

    ... Registration, Boehringer Ingelheim Chemicals By Notice dated June 18, 2013, and published in the Federal Register on July 1, 2013, 78 FR 39337, Boehringer Ingelheim Chemicals, 2820 N. Normandy Drive, Petersburg...) and determined that the registration of Boehringer Ingelheim Chemicals is consistent with the public...

  3. 28 CFR 75.6 - Statement describing location of books and records.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Statement describing location of books... of books and records. (a) Any producer of any book, magazine, periodical, film, videotape, digitally... the book, magazine, periodical, film, videotape, digitally- or computer-manipulated image, digital...

  4. 28 CFR 75.6 - Statement describing location of books and records.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Statement describing location of books... of books and records. (a) Any producer of any book, magazine, periodical, film, videotape, digitally... the book, magazine, periodical, film, videotape, digitally- or computer-manipulated image, digital...

  5. 28 CFR 75.6 - Statement describing location of books and records.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Statement describing location of books... of books and records. (a) Any producer of any book, magazine, periodical, film, videotape, digitally... the book, magazine, periodical, film, videotape, digitally- or computer-manipulated image, digital...

  6. 28 CFR 75.6 - Statement describing location of books and records.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Statement describing location of books... of books and records. (a) Any producer of any book, magazine, periodical, film, videotape, digitally... the book, magazine, periodical, film, videotape, digitally- or computer-manipulated image, digital...

  7. 14 CFR 47.43 - Invalid registration.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... REGISTRATION Certificates of Aircraft Registration § 47.43 Invalid registration. (a) The registration of an...) compliance with 49 U.S.C. 44101-44104. (b) If the registration of an aircraft is invalid under paragraph (a) of this section, the holder of the invalid Certificate of Aircraft Registration shall return it as...

  8. 21 CFR 1301.52 - Termination of registration; transfer of registration; distribution upon discontinuance of business.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... discontinues business or professional practice. Any registrant who ceases legal existence or discontinues... registration; distribution upon discontinuance of business. 1301.52 Section 1301.52 Food and Drugs DRUG... of registration; transfer of registration; distribution upon discontinuance of business. (a) Except...

  9. Can hexazine (N6) be stable?

    NASA Astrophysics Data System (ADS)

    Ha, Tae-Kyu; Cimiraglia, R.; Nguyen, Minh Tho

    1981-10-01

    Ab initio SCF and CI calculations are reported for n6 in D6h symmetry. The result confirms previous calculations that free N6 is not stable. The calculated (n → π*)1 transition energy at 391 nm is in agreement with λmax = 380 nm observed in absorption in the condensed phase. It is conjectured that N6 may be formed as a short-lived species in a matrix at low temperatures during photochemical reaction.

  10. 14 CFR 47.43 - Invalid registration.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... REGISTRATION Certificates of Aircraft Registration § 47.43 Invalid registration. (a) The registration of an...) compliance with 49 U.S.C. 44101-44104. (b) If the registration of an aircraft is invalid under paragraph (a) of this section, the holder of the invalid Certificate of Aircraft Registration, AC Form 8050-3, must...

  11. 14 CFR 47.43 - Invalid registration.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... REGISTRATION Certificates of Aircraft Registration § 47.43 Invalid registration. (a) The registration of an...) compliance with 49 U.S.C. 44101-44104. (b) If the registration of an aircraft is invalid under paragraph (a) of this section, the holder of the invalid Certificate of Aircraft Registration, AC Form 8050-3, must...

  12. Have personal statements become impersonal? An evaluation of personal statements in anesthesiology residency applications.

    PubMed

    Max, Bryan A; Gelfand, Brian; Brooks, Meredith R; Beckerly, Rena; Segal, Scott

    2010-08-01

    To evaluate personal statements submitted to a major academic anesthesiology program to determine the prevalence of common features and overall subjective quality, and to survey anesthesiology program directors as to how they utilized these statements during the resident selection process. Structured analysis of de-identified personal statements and Internet-based survey of program directors. Large academic anesthesiology training program. 670 applicant personal statements and academic anesthesiology program directors. Prevalence of 13 specific essay features and 8 quality ratings were calculated for the essays and correlated with other aspects of the residency application, as abstracted from the Electronic Residency Application Service (ERAS) files. A 6-question survey regarding use of personal statements was collected from program directors. 70 of 131 program directors queried responded to our survey. Interest in physiology and pharmacology, enjoyment of a hands-on specialty, and desire to comfort anxious patients were each mentioned in more than half of the essays. Candidates invited for an interview had essays that received higher quality ratings than essays of those not invited (P = 0.02 to P < 0.0001). Higher quality ratings were also strongly associated with graduation from a U.S. or Canadian medical school, applicant file screening score, female gender, and younger age. Interrater reliability was good (kappa 0.75-0.99 for structural features, and 0.45-0.65 for quality features). More than 90% of program directors found proper use of English to be a somewhat or very important feature of the essay. Only 41% found the personal statement to be very or somewhat important in selecting candidates for interview invitations. However, over 90% stated that they used the statements during actual interviews with invited applicants. The data showed a high prevalence of common features found within personal statements and a general ambivalence amongst those program

  13. 28 CFR 75.6 - Statement describing location of books and records.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...- or computer-manipulated image, digital image, or picture, or other matter (including but not limited... the book, magazine, periodical, film, videotape, digitally- or computer-manipulated image, digital image, picture, or other matter to affix the statement. In this paragraph, the term “copy” includes...

  14. A quality analysis of clinical anaesthesia study protocols from the Chinese clinical trials registry according to the SPIRIT statement.

    PubMed

    Yang, Lei; Chen, Shouming; Yang, Di; Li, Jiajin; Wu, Taixiang; Zuo, Yunxia

    2018-05-15

    To learn about the overall quality of clinical anaesthesia study protocols from the Chinese Clinical Trials Registry and to discuss the way to improve study protocol quality. We defined completeness of each sub-item in SPIRIT as N/A (not applicable) or with a score of 0, 1, or 2. For each protocol, we calculated the proportion of adequately reported items (score = 2 and N/A) and unreported items (score = 0). Protocol quality was determined according to the proportion of reported items, with values >50% indicating high quality. Protocol quality was determined according to the proportion of reported items. For each sub-item in SPIRIT, we calculated the adequately reported rate (percentage of all protocols with score 2 and NA on one sub-item) as well as the unreported rate (percentage of all protocols with score 0 on one sub-item). Total 126 study protocols were available for assessment. Among these, 88.1% were assessed as being of low quality. By comparison, the percentage of low-quality protocols was 88.9% after the publication of the SPIRIT statement. Among the 51 SPIRIT sub-items, 18 sub-items had an unreported rate above 90% while 16 had a higher adequately reported rate than an unreported rate. The overall quality of clinical anaesthesia study protocols registered in the ChiCTR was poor. A mandatory protocol upload and self-check based on the SPIRIT statement during the trial registration process may improve protocol quality in the future.

  15. 32 CFR 1615.1 - Registration.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... registration card or other method of registration prescribed by the Director of Selective Service by a person... method of registration prescribed by the Director, he shall advise in writing the Selective Service System, P.O. Box 94638, Palatine, IL 60094-4638. (c) The methods of registration prescribed by the...

  16. Evaluation of 14 nonlinear deformation algorithms applied to human brain MRI registration

    PubMed Central

    Klein, Arno; Andersson, Jesper; Ardekani, Babak A.; Ashburner, John; Avants, Brian; Chiang, Ming-Chang; Christensen, Gary E.; Collins, D. Louis; Gee, James; Hellier, Pierre; Song, Joo Hyun; Jenkinson, Mark; Lepage, Claude; Rueckert, Daniel; Thompson, Paul; Vercauteren, Tom; Woods, Roger P.; Mann, J. John; Parsey, Ramin V.

    2009-01-01

    All fields of neuroscience that employ brain imaging need to communicate their results with reference to anatomical regions. In particular, comparative morphometry and group analysis of functional and physiological data require coregistration of brains to establish correspondences across brain structures. It is well established that linear registration of one brain to another is inadequate for aligning brain structures, so numerous algorithms have emerged to nonlinearly register brains to one another. This study is the largest evaluation of nonlinear deformation algorithms applied to brain image registration ever conducted. Fourteen algorithms from laboratories around the world are evaluated using 8 different error measures. More than 45,000 registrations between 80 manually labeled brains were performed by algorithms including: AIR, ANIMAL, ART, Diffeomorphic Demons, FNIRT, IRTK, JRD-fluid, ROMEO, SICLE, SyN, and four different SPM5 algorithms (“SPM2-type” and regular Normalization, Unified Segmentation, and the DARTEL Toolbox). All of these registrations were preceded by linear registration between the same image pairs using FLIRT. One of the most significant findings of this study is that the relative performances of the registration methods under comparison appear to be little affected by the choice of subject population, labeling protocol, and type of overlap measure. This is important because it suggests that the findings are generalizable to new subject populations that are labeled or evaluated using different labeling protocols. Furthermore, we ranked the 14 methods according to three completely independent analyses (permutation tests, one-way ANOVA tests, and indifference-zone ranking) and derived three almost identical top rankings of the methods. ART, SyN, IRTK, and SPM's DARTEL Toolbox gave the best results according to overlap and distance measures, with ART and SyN delivering the most consistently high accuracy across subjects and label sets

  17. Improving registration accuracy.

    PubMed

    Murphy, J Patrick; Shorrosh, Paul

    2008-04-01

    A registration quality assurance initiative--whether manual or automated--can result in benefits such as: Cleaner claims, Reduced cost to collect, Enhanced revenue, Decreased registration, error rates, Improved staff morale, Fewer customer complaints

  18. Overlay improvement by exposure map based mask registration optimization

    NASA Astrophysics Data System (ADS)

    Shi, Irene; Guo, Eric; Chen, Ming; Lu, Max; Li, Gordon; Li, Rivan; Tian, Eric

    2015-03-01

    Along with the increased miniaturization of semiconductor electronic devices, the design rules of advanced semiconductor devices shrink dramatically. [1] One of the main challenges of lithography step is the layer-to-layer overlay control. Furthermore, DPT (Double Patterning Technology) has been adapted for the advanced technology node like 28nm and 14nm, corresponding overlay budget becomes even tighter. [2][3] After the in-die mask registration (pattern placement) measurement is introduced, with the model analysis of a KLA SOV (sources of variation) tool, it's observed that registration difference between masks is a significant error source of wafer layer-to-layer overlay at 28nm process. [4][5] Mask registration optimization would highly improve wafer overlay performance accordingly. It was reported that a laser based registration control (RegC) process could be applied after the pattern generation or after pellicle mounting and allowed fine tuning of the mask registration. [6] In this paper we propose a novel method of mask registration correction, which can be applied before mask writing based on mask exposure map, considering the factors of mask chip layout, writing sequence, and pattern density distribution. Our experiment data show if pattern density on the mask keeps at a low level, in-die mask registration residue error in 3sigma could be always under 5nm whatever blank type and related writer POSCOR (position correction) file was applied; it proves random error induced by material or equipment would occupy relatively fixed error budget as an error source of mask registration. On the real production, comparing the mask registration difference through critical production layers, it could be revealed that registration residue error of line space layers with higher pattern density is always much larger than the one of contact hole layers with lower pattern density. Additionally, the mask registration difference between layers with similar pattern density

  19. 21 CFR 1311.45 - Requirements for registrants that allow powers of attorney to obtain CSOS digital certificates...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... attorney to obtain CSOS digital certificates under their DEA registration. 1311.45 Section 1311.45 Food and... registrants that allow powers of attorney to obtain CSOS digital certificates under their DEA registration. (a) A registrant that grants power of attorney must report to the DEA Certification Authority within 6...

  20. Demons deformable registration for CBCT-guided procedures in the head and neck: Convergence and accuracy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nithiananthan, S.; Brock, K. K.; Daly, M. J.

    2009-10-15

    Purpose: The accuracy and convergence behavior of a variant of the Demons deformable registration algorithm were investigated for use in cone-beam CT (CBCT)-guided procedures of the head and neck. Online use of deformable registration for guidance of therapeutic procedures such as image-guided surgery or radiation therapy places trade-offs on accuracy and computational expense. This work describes a convergence criterion for Demons registration developed to balance these demands; the accuracy of a multiscale Demons implementation using this convergence criterion is quantified in CBCT images of the head and neck. Methods: Using an open-source ''symmetric'' Demons registration algorithm, a convergence criterion basedmore » on the change in the deformation field between iterations was developed to advance among multiple levels of a multiscale image pyramid in a manner that optimized accuracy and computation time. The convergence criterion was optimized in cadaver studies involving CBCT images acquired using a surgical C-arm prototype modified for 3D intraoperative imaging. CBCT-to-CBCT registration was performed and accuracy was quantified in terms of the normalized cross-correlation (NCC) and target registration error (TRE). The accuracy and robustness of the algorithm were then tested in clinical CBCT images of ten patients undergoing radiation therapy of the head and neck. Results: The cadaver model allowed optimization of the convergence factor and initial measurements of registration accuracy: Demons registration exhibited TRE=(0.8{+-}0.3) mm and NCC=0.99 in the cadaveric head compared to TRE=(2.6{+-}1.0) mm and NCC=0.93 with rigid registration. Similarly for the patient data, Demons registration gave mean TRE=(1.6{+-}0.9) mm compared to rigid registration TRE=(3.6{+-}1.9) mm, suggesting registration accuracy at or near the voxel size of the patient images (1x1x2 mm{sup 3}). The multiscale implementation based on optimal convergence criteria completed

  1. Demons deformable registration for CBCT-guided procedures in the head and neck: Convergence and accuracy

    PubMed Central

    Nithiananthan, S.; Brock, K. K.; Daly, M. J.; Chan, H.; Irish, J. C.; Siewerdsen, J. H.

    2009-01-01

    Purpose: The accuracy and convergence behavior of a variant of the Demons deformable registration algorithm were investigated for use in cone-beam CT (CBCT)-guided procedures of the head and neck. Online use of deformable registration for guidance of therapeutic procedures such as image-guided surgery or radiation therapy places trade-offs on accuracy and computational expense. This work describes a convergence criterion for Demons registration developed to balance these demands; the accuracy of a multiscale Demons implementation using this convergence criterion is quantified in CBCT images of the head and neck. Methods: Using an open-source “symmetric” Demons registration algorithm, a convergence criterion based on the change in the deformation field between iterations was developed to advance among multiple levels of a multiscale image pyramid in a manner that optimized accuracy and computation time. The convergence criterion was optimized in cadaver studies involving CBCT images acquired using a surgical C-arm prototype modified for 3D intraoperative imaging. CBCT-to-CBCT registration was performed and accuracy was quantified in terms of the normalized cross-correlation (NCC) and target registration error (TRE). The accuracy and robustness of the algorithm were then tested in clinical CBCT images of ten patients undergoing radiation therapy of the head and neck. Results: The cadaver model allowed optimization of the convergence factor and initial measurements of registration accuracy: Demons registration exhibited TRE=(0.8±0.3) mm and NCC=0.99 in the cadaveric head compared to TRE=(2.6±1.0) mm and NCC=0.93 with rigid registration. Similarly for the patient data, Demons registration gave mean TRE=(1.6±0.9) mm compared to rigid registration TRE=(3.6±1.9) mm, suggesting registration accuracy at or near the voxel size of the patient images (1×1×2 mm3). The multiscale implementation based on optimal convergence criteria completed registration in 52 s for

  2. Petition for Rulemaking to Evaluate Synergestic Effects of Pesticides during Registration and Registration Review

    EPA Pesticide Factsheets

    This petition from the Center for Biological Diversity asks that the Agency require all applicants and registrants to provide data on the potential synergistic effects of pesticides during the registration and registration review processes.

  3. Transparency of outcome reporting and trial registration of randomized controlled trials in top psychosomatic and behavioral health journals: A systematic review.

    PubMed

    Milette, Katherine; Roseman, Michelle; Thombs, Brett D

    2011-03-01

    The most reliable evidence for evaluating healthcare interventions comes from well-designed and conducted randomized controlled trials (RCTs). The extent to which published RCTs reflect the efficacy of interventions, however, depends on the completeness and accuracy of published results. The Consolidated Standards of Reporting Trials statement, initially developed in 1996, provides guidelines intended to improve the transparency of published RCT reports. A policy of the International Committee of Medical Journal Editors, initiated in 2005, requires clinical trials published in member journals to be registered in publicly accessible registries prior to patient enrollment. The objective of this study was to assess the clarity of outcome reporting, proportion of registered trials, and adequacy of outcome registration in RCTs published in top behavioral health journals. Eligible studies were primary or secondary reports of RCTs published in Annals of Behavioral Medicine, Health Psychology, Journal of Psychosomatic Research, and Psychosomatic Medicine from January 2008 to September 2009. Data were extracted for each study on adequacy of outcome reporting and registration. Of 63 articles reviewed, only 25 (39.7%) had adequately declared primary or secondary outcomes, whereas 38 (60.3%) had multiple primary outcomes or did not define outcomes. Only 13 studies (20.6%) were registered. Only 1 study registered sufficiently precise outcome information to compare with published outcomes, and registered and published outcomes were discrepant in that study. Greater attention to outcome reporting and trial registration by researchers, peer reviewers, and journal editors will increase the likelihood that effective behavioral health interventions are readily identified and made available to patients. Copyright © 2011 Elsevier Inc. All rights reserved.

  4. Off-Campus Registration Procedures.

    ERIC Educational Resources Information Center

    Maas, Michael L.

    Registration is one of the more critical functions that a college staff encounters each semester. To have a smooth, efficient, college-wide registration, it is essential that all segments of the college be aware of registration procedures as well as data control operations. This packet was designed to acquaint interested parties with the…

  5. Registration Review Process

    EPA Pesticide Factsheets

    EPA will review each registered pesticide at least every 15 years to determine whether it continues to meet the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) standard for registration. There are currently 745 registration review cases.

  6. Clinical trial registration in physical therapy journals: a cross-sectional study.

    PubMed

    Babu, Abraham Samuel; Veluswamy, Sundar Kumar; Rao, Pratiksha Tilak; Maiya, Arun G

    2014-01-01

    Clinical trial registration has become an important part of editorial policies of various biomedical journals, including a few physical therapy journals. However, the extent to which editorial boards enforce the need for trial registration varies across journals. The purpose of this study was to identify editorial policies and reporting of trial registration details in MEDLINE-indexed English-language physical therapy journals. This study was carried out using a cross-sectional design. Editorial policies on trial registration of MEDLINE-indexed member journals of the International Society of Physiotherapy Journal Editors (ISPJE) (Journal of Geriatric Physical Therapy, Journal of Hand Therapy, Journal of Neurologic Physical Therapy, Journal of Orthopaedic and Sports Physical Therapy, Journal of Physiotherapy [formerly Australian Journal of Physiotherapy], Journal of Science and Medicine in Sport, Manual Therapy, Physical Therapy, Physical Therapy in Sport, Physiotherapy, Physiotherapy Research International, Physiotherapy Theory and Practice, and Revista Brasileira de Fisioterapia) were reviewed in April 2013. Full texts of reports of clinical trials published in these journals between January 1, 2008, and December 31, 2012, were independently assessed for information on trial registration. Among the 13 journals, 8 recommended trial registration, and 6 emphasized prospective trial registration. As of April 2013, 4,618 articles were published between January 2008 and December 2012, of which 9% (417) were clinical trials and 29% (121/417) of these reported trial registration details. A positive trend in reporting of trial registration was observed from 2008 to 2012. The study was limited to MEDLINE-indexed ISPJE member journals. Editorial policies on trial registration of physical therapy journals and a rising trend toward reporting of trial registration details indicate a positive momentum toward trial registration. Physical therapy journal editors need to show

  7. 16 CFR § 1130.8 - Requirements for Web site registration or alternative e-mail registration.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 16 Commercial Practices 2 2013-01-01 2013-01-01 false Requirements for Web site registration or... OR TODDLER PRODUCTS § 1130.8 Requirements for Web site registration or alternative e-mail registration. (a) Link to registration page. The manufacturer's Web site, or other Web site established for the...

  8. 26 CFR 1.408-6 - Disclosure statements for individual retirement arrangements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... copy of the governing instrument to be used in establishing the account, annuity, or endowment contract. The copy of such governing instrument need not be filled in with financial and other data pertaining... disclosure statement and copy of the governing instrument must be received by the benefited individual at...

  9. 40 CFR 155.42 - Registration review cases.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 25 2012-07-01 2012-07-01 false Registration review cases. 155.42... REGISTRATION STANDARDS AND REGISTRATION REVIEW Registration Review Procedures § 155.42 Registration review cases. (a) Establishing registration review cases. A registration review case will be composed of one or...

  10. 40 CFR 155.42 - Registration review cases.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 25 2013-07-01 2013-07-01 false Registration review cases. 155.42... REGISTRATION STANDARDS AND REGISTRATION REVIEW Registration Review Procedures § 155.42 Registration review cases. (a) Establishing registration review cases. A registration review case will be composed of one or...

  11. 40 CFR 155.42 - Registration review cases.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 24 2011-07-01 2011-07-01 false Registration review cases. 155.42... REGISTRATION STANDARDS AND REGISTRATION REVIEW Registration Review Procedures § 155.42 Registration review cases. (a) Establishing registration review cases. A registration review case will be composed of one or...

  12. 40 CFR 155.42 - Registration review cases.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 24 2014-07-01 2014-07-01 false Registration review cases. 155.42... REGISTRATION STANDARDS AND REGISTRATION REVIEW Registration Review Procedures § 155.42 Registration review cases. (a) Establishing registration review cases. A registration review case will be composed of one or...

  13. 40 CFR 155.42 - Registration review cases.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Registration review cases. 155.42... REGISTRATION STANDARDS AND REGISTRATION REVIEW Registration Review Procedures § 155.42 Registration review cases. (a) Establishing registration review cases. A registration review case will be composed of one or...

  14. Image registration with uncertainty analysis

    DOEpatents

    Simonson, Katherine M [Cedar Crest, NM

    2011-03-22

    In an image registration method, edges are detected in a first image and a second image. A percentage of edge pixels in a subset of the second image that are also edges in the first image shifted by a translation is calculated. A best registration point is calculated based on a maximum percentage of edges matched. In a predefined search region, all registration points other than the best registration point are identified that are not significantly worse than the best registration point according to a predetermined statistical criterion.

  15. Image Registration Workshop Proceedings

    NASA Technical Reports Server (NTRS)

    LeMoigne, Jacqueline (Editor)

    1997-01-01

    Automatic image registration has often been considered as a preliminary step for higher-level processing, such as object recognition or data fusion. But with the unprecedented amounts of data which are being and will continue to be generated by newly developed sensors, the very topic of automatic image registration has become and important research topic. This workshop presents a collection of very high quality work which has been grouped in four main areas: (1) theoretical aspects of image registration; (2) applications to satellite imagery; (3) applications to medical imagery; and (4) image registration for computer vision research.

  16. A Remote Registration Based on MIDAS

    NASA Astrophysics Data System (ADS)

    JIN, Xin

    2017-04-01

    We often need for software registration to protect the interests of the software developers. This article narrated one kind of software long-distance registration technology. The registration method is: place the registration information in a database table, after the procedure starts in check table registration information, if it has registered then the procedure may the normal operation; Otherwise, the customer must input the sequence number and registers through the network on the long-distance server. If it registers successfully, then records the registration information in the database table. This remote registration method can protect the rights of software developers.

  17. DIRBoost-an algorithm for boosting deformable image registration: application to lung CT intra-subject registration.

    PubMed

    Muenzing, Sascha E A; van Ginneken, Bram; Viergever, Max A; Pluim, Josien P W

    2014-04-01

    We introduce a boosting algorithm to improve on existing methods for deformable image registration (DIR). The proposed DIRBoost algorithm is inspired by the theory on hypothesis boosting, well known in the field of machine learning. DIRBoost utilizes a method for automatic registration error detection to obtain estimates of local registration quality. All areas detected as erroneously registered are subjected to boosting, i.e. undergo iterative registrations by employing boosting masks on both the fixed and moving image. We validated the DIRBoost algorithm on three different DIR methods (ANTS gSyn, NiftyReg, and DROP) on three independent reference datasets of pulmonary image scan pairs. DIRBoost reduced registration errors significantly and consistently on all reference datasets for each DIR algorithm, yielding an improvement of the registration accuracy by 5-34% depending on the dataset and the registration algorithm employed. Copyright © 2014 Elsevier B.V. All rights reserved.

  18. Consistency-based rectification of nonrigid registrations

    PubMed Central

    Gass, Tobias; Székely, Gábor; Goksel, Orcun

    2015-01-01

    Abstract. We present a technique to rectify nonrigid registrations by improving their group-wise consistency, which is a widely used unsupervised measure to assess pair-wise registration quality. While pair-wise registration methods cannot guarantee any group-wise consistency, group-wise approaches typically enforce perfect consistency by registering all images to a common reference. However, errors in individual registrations to the reference then propagate, distorting the mean and accumulating in the pair-wise registrations inferred via the reference. Furthermore, the assumption that perfect correspondences exist is not always true, e.g., for interpatient registration. The proposed consistency-based registration rectification (CBRR) method addresses these issues by minimizing the group-wise inconsistency of all pair-wise registrations using a regularized least-squares algorithm. The regularization controls the adherence to the original registration, which is additionally weighted by the local postregistration similarity. This allows CBRR to adaptively improve consistency while locally preserving accurate pair-wise registrations. We show that the resulting registrations are not only more consistent, but also have lower average transformation error when compared to known transformations in simulated data. On clinical data, we show improvements of up to 50% target registration error in breathing motion estimation from four-dimensional MRI and improvements in atlas-based segmentation quality of up to 65% in terms of mean surface distance in three-dimensional (3-D) CT. Such improvement was observed consistently using different registration algorithms, dimensionality (two-dimensional/3-D), and modalities (MRI/CT). PMID:26158083

  19. Assessment of Registration Information on Methodological Design of Acupuncture RCTs: A Review of 453 Registration Records Retrieved from WHO International Clinical Trials Registry Platform

    PubMed Central

    Gu, Jing; Wang, Qi; Wang, Xiaogang; Li, Hailong; Gu, Mei; Ming, Haixia; Dong, Xiaoli; Yang, Kehu; Wu, Hongyan

    2014-01-01

    Background. This review provides the first methodological information assessment of protocol of acupuncture RCTs registered in WHO International Clinical Trials Registry Platform (ICTRP). Methods. All records of acupuncture RCTs registered in the ICTRP have been collected. The methodological design assessment involved whether the randomization methods, allocation concealment, and blinding were adequate or not based on the information of registration records (protocols of acupuncture RCTs). Results. A total of 453 records, found in 11 registries, were examined. Methodological details were insufficient in registration records; there were 76.4%, 89.0%, and 21.4% records that did not provide information on randomization methods, allocation concealment, and blinding respectively. The proportions of adequate randomization methods, allocation concealment, and blinding were only 107 (23.6%), 48 (10.6%), and 210 (46.4%), respectively. The methodological design improved year by year, especially after 2007. Additionally, methodology of RCTs with ethics approval was clearly superior to those without ethics approval and different among registries. Conclusions. The overall methodological design based on registration records of acupuncture RCTs is not very well but improved year by year. The insufficient information on randomization methods, allocation concealment, and blinding maybe due to the relevant description is not taken seriously in acupuncture RCTs' registration. PMID:24688591

  20. Assessment of Registration Information on Methodological Design of Acupuncture RCTs: A Review of 453 Registration Records Retrieved from WHO International Clinical Trials Registry Platform.

    PubMed

    Gu, Jing; Wang, Qi; Wang, Xiaogang; Li, Hailong; Gu, Mei; Ming, Haixia; Dong, Xiaoli; Yang, Kehu; Wu, Hongyan

    2014-01-01

    Background. This review provides the first methodological information assessment of protocol of acupuncture RCTs registered in WHO International Clinical Trials Registry Platform (ICTRP). Methods. All records of acupuncture RCTs registered in the ICTRP have been collected. The methodological design assessment involved whether the randomization methods, allocation concealment, and blinding were adequate or not based on the information of registration records (protocols of acupuncture RCTs). Results. A total of 453 records, found in 11 registries, were examined. Methodological details were insufficient in registration records; there were 76.4%, 89.0%, and 21.4% records that did not provide information on randomization methods, allocation concealment, and blinding respectively. The proportions of adequate randomization methods, allocation concealment, and blinding were only 107 (23.6%), 48 (10.6%), and 210 (46.4%), respectively. The methodological design improved year by year, especially after 2007. Additionally, methodology of RCTs with ethics approval was clearly superior to those without ethics approval and different among registries. Conclusions. The overall methodological design based on registration records of acupuncture RCTs is not very well but improved year by year. The insufficient information on randomization methods, allocation concealment, and blinding maybe due to the relevant description is not taken seriously in acupuncture RCTs' registration.

  1. 14 CFR 47.43 - Invalid registration.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... REGISTRATION Certificates of Aircraft Registration § 47.43 Invalid registration. Link to an amendment published... registration of an aircraft is invalid if, at the time it is made— (1) The aircraft is registered in a foreign... knowledge) compliance with 49 U.S.C. 44101-44104. (b) If the registration of an aircraft is invalid under...

  2. Infrared Spectroscopy of C_6D_6-Rg_n(n=1,2)

    NASA Astrophysics Data System (ADS)

    George, Jobin; Yousefi, Mahdi; Rezaei, Mojtaba; McKellar, Bob; Moazzen-Ahmadi, Nasser

    2014-06-01

    Benzene-noble gas complexes were one of the earliest topics of interest in spectroscopic investigation of van der Waals (vdW) complexes. Smalley et al. observed C_6H_6-(He)1,2 vdW complexes in the late 1970s by means of electronic spectroscopy. A recent study on the same species was done by M. Hayashi et al. Here, we present the infrared observation of C_6D_6-Rg_n (n=1,2) with the rare gas being He, Ne, or Ar, in the regions of νb{12} fundamental band of C_6D_6 (˜2289 wn) and the νb{2} + νb{13} combination band (˜2275 wn) which are coupled by a Fermi resonance. The spectra were observed at a resolution of 60 MHz using a tunable optical parametric oscillator to probe a pulsed supersonic-jet expansion from a slit nozzle. In the case of C_6D_6-Rg dimers, the spectra were assigned to a symmetric top with C6v symmetry with the rare gas atom being located on the C6 symmetry axis. To observe C_6D_6-Rg_2 trimers, the nozzle was cooled using a closed-cycle methanol refrigerator and the spectra were simulated with a rotational temperature of 1.3K. The spectra of the C_6D_6-Rg_2 trimers were in agreement with a D6h symmetry structure, where the rare gas atoms are positioned above and below the C_6D_6 plane. Data analysis and observation are presently ongoing. S. M. Beck, M. G. Liverman, D. L. Monts and R. E. Smalley, J. Chem. Phys. 70, 232 (1979). M. Hayashi, Y. Ohshima, Chem. Phys. 419, 131 (2013).

  3. Image Registration: A Necessary Evil

    NASA Technical Reports Server (NTRS)

    Bell, James; McLachlan, Blair; Hermstad, Dexter; Trosin, Jeff; George, Michael W. (Technical Monitor)

    1995-01-01

    Registration of test and reference images is a key component of nearly all PSP data reduction techniques. This is done to ensure that a test image pixel viewing a particular point on the model is ratioed by the reference image pixel which views the same point. Typically registration is needed to account for model motion due to differing airloads when the wind-off and wind-on images are taken. Registration is also necessary when two cameras are used for simultaneous acquisition of data from a dual-frequency paint. This presentation will discuss the advantages and disadvantages of several different image registration techniques. In order to do so, it is necessary to propose both an accuracy requirement for image registration and a means for measuring the accuracy of a particular technique. High contrast regions in the unregistered images are most sensitive to registration errors, and it is proposed that these regions be used to establish the error limits for registration. Once this is done, the actual registration error can be determined by locating corresponding points on the test and reference images, and determining how well a particular registration technique matches them. An example of this procedure is shown for three transforms used to register images of a semispan model. Thirty control points were located on the model. A subset of the points were used to determine the coefficients of each registration transform, and the error with which each transform aligned the remaining points was determined. The results indicate the general superiority of a third-order polynomial over other candidate transforms, as well as showing how registration accuracy varies with number of control points. Finally, it is proposed that image registration may eventually be done away with completely. As more accurate image resection techniques and more detailed model surface grids become available, it will be possible to map raw image data onto the model surface accurately. Intensity

  4. PROFESSIONAL REGISTRATION OF GOVERNMENT ENGINEERS.

    USGS Publications Warehouse

    Buchanan, Thomas J.

    1985-01-01

    The American Society of Civil Engineers views professional registration as an appropriate requirement for engineers, including those in government. The National Society of Professional Engineers makes registration a requirement for the grade of member and full privileges in the society. Some Federal agencies require engineering registration for certain positions in their agencies. Engineers in government service should consider the value of engineering registration to themselves and to their agencies and take pride in their professions and in their own capabilities by becoming registered engineers. They should also take steps to encourage their agencies to give more attention to engineering registration.

  5. 77 FR 30027 - Manufacturer of Controlled Substances; Notice of Registration; Siegfried (USA)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-21

    ...; Notice of Registration; Siegfried (USA) By Notice dated January 6, 2012, and published in the Federal Register on January 17, 2012, 77 FR 2323, Siegfried (USA), 33 Industrial Park Road, Pennsville, New Jersey... U.S.C. 823(a) and determined that the registration of Siegfried (USA), to manufacture the listed...

  6. 75 FR 69434 - Environmental Impacts Statements; Notice of Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-12

    ... ENVIRONMENTAL PROTECTION AGENCY [ER-FRL-8993-6] Environmental Impacts Statements; Notice of Availability Responsible Agency: Office of Federal Activities, General Information (202) 564-1399 or http://www.epa.gov/compliance/nepa/ . Weekly receipt of Environmental Impact Statements Filed 11/01/2010 Through...

  7. 76 FR 80367 - Environmental Impacts Statements; Notice of Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-23

    ... ENVIRONMENTAL PROTECTION AGENCY [ER-FRL-9000-6] Environmental Impacts Statements; Notice of Availability Responsible Agency: Office of Federal Activities, General Information (202) 564-1399 or http://www.epa.gov/compliance/nepa/ . Weekly receipt of Environmental Impact Statements Filed 12/12/2011 Through...

  8. 78 FR 35928 - Environmental Impacts Statements; Notice of Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-14

    ... ENVIRONMENTAL PROTECTION AGENCY [ER-FRL-9009-6] Environmental Impacts Statements; Notice of Availability Responsible Agency: Office of Federal Activities, General Information (202) 564-7146 or http://www.epa.gov/compliance/nepa/ . Weekly receipt of Environmental Impact Statements Filed 06/03/2013 through...

  9. 78 FR 21938 - Environmental Impacts Statements; Notice of Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-12

    ... ENVIRONMENTAL PROTECTION AGENCY [ER-FRL-9008-6] Environmental Impacts Statements; Notice of Availability Responsible Agency: Office of Federal Activities, General Information (202) 564-7146 or http://www.epa.gov/compliance/nepa/ . Weekly receipt of Environmental Impact Statements Filed 04/01/2013 Through...

  10. 40 CFR 155.57 - Registration review decision.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Registration review decision. 155.57... REGISTRATION STANDARDS AND REGISTRATION REVIEW Registration Review Procedures § 155.57 Registration review decision. A registration review decision is the Agency's determination whether a pesticide meets, or does...

  11. TU-B-19A-01: Image Registration II: TG132-Quality Assurance for Image Registration

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brock, K; Mutic, S

    2014-06-15

    AAPM Task Group 132 was charged with a review of the current approaches and solutions for image registration in radiotherapy and to provide recommendations for quality assurance and quality control of these clinical processes. As the results of image registration are always used as the input of another process for planning or delivery, it is important for the user to understand and document the uncertainty associate with the algorithm in general and the Result of a specific registration. The recommendations of this task group, which at the time of abstract submission are currently being reviewed by the AAPM, include themore » following components. The user should understand the basic image registration techniques and methods of visualizing image fusion. The disclosure of basic components of the image registration by commercial vendors is critical in this respect. The physicists should perform end-to-end tests of imaging, registration, and planning/treatment systems if image registration is performed on a stand-alone system. A comprehensive commissioning process should be performed and documented by the physicist prior to clinical use of the system. As documentation is important to the safe implementation of this process, a request and report system should be integrated into the clinical workflow. Finally, a patient specific QA practice should be established for efficient evaluation of image registration results. The implementation of these recommendations will be described and illustrated during this educational session. Learning Objectives: Highlight the importance of understanding the image registration techniques used in their clinic. Describe the end-to-end tests needed for stand-alone registration systems. Illustrate a comprehensive commissioning program using both phantom data and clinical images. Describe a request and report system to ensure communication and documentation. Demonstrate an clinically-efficient patient QA practice for efficient evaluation

  12. SU-E-J-29: Automatic Image Registration Performance of Three IGRT Systems for Prostate Radiotherapy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Barber, J; University of Sydney, Sydney, NSW; Sykes, J

    Purpose: To compare the performance of an automatic image registration algorithm on image sets collected on three commercial image guidance systems, and explore its relationship with imaging parameters such as dose and sharpness. Methods: Images of a CIRS Virtually Human Male Pelvis phantom (VHMP) were collected on the CBCT systems of Varian TrueBeam/OBI and Elekta Synergy/XVI linear accelerators, across a range of mAs settings; and MVCT on a Tomotherapy Hi-ART accelerator with a range of pitch. Using the 6D correlation ratio algorithm of XVI, each image was registered to a mask of the prostate volume with a 5 mm expansion.more » Registrations were repeated 100 times, with random initial offsets introduced to simulate daily matching. Residual registration errors were calculated by correcting for the initial phantom set-up error. Automatic registration was also repeated after reconstructing images with different sharpness filters. Results: All three systems showed good registration performance, with residual translations <0.5mm (1σ) for typical clinical dose and reconstruction settings. Residual rotational error had larger range, with 0.8°, 1.2° and 1.9° for 1σ in XVI, OBI and Tomotherapy respectively. The registration accuracy of XVI images showed a strong dependence on imaging dose, particularly below 4mGy. No evidence of reduced performance was observed at the lowest dose settings for OBI and Tomotherapy, but these were above 4mGy. Registration failures (maximum target registration error > 3.6 mm on the surface of a 30mm sphere) occurred in 5% to 10% of registrations. Changing the sharpness of image reconstruction had no significant effect on registration performance. Conclusions: Using the present automatic image registration algorithm, all IGRT systems tested provided satisfactory registrations for clinical use, within a normal range of acquisition settings.« less

  13. 78 FR 64018 - Manufacturer of Controlled Substances; Notice of Registration; Boehringer Ingelheim Chemicals, Inc.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-25

    ...; Notice of Registration; Boehringer Ingelheim Chemicals, Inc. By Notice dated June 18, 2013, and published in the Federal Register on July 1, 2013, 78 FR 39340, Boehringer Ingelheim Chemicals, Inc., 2820 N... 21 U.S.C. 823(a) and determined that the registration of Boehringer Ingelheim Chemicals, Inc., to...

  14. Registration of 3D spectral OCT volumes using 3D SIFT feature point matching

    NASA Astrophysics Data System (ADS)

    Niemeijer, Meindert; Garvin, Mona K.; Lee, Kyungmoo; van Ginneken, Bram; Abràmoff, Michael D.; Sonka, Milan

    2009-02-01

    The recent introduction of next generation spectral OCT scanners has enabled routine acquisition of high resolution, 3D cross-sectional volumetric images of the retina. 3D OCT is used in the detection and management of serious eye diseases such as glaucoma and age-related macular degeneration. For follow-up studies, image registration is a vital tool to enable more precise, quantitative comparison of disease states. This work presents a registration method based on a recently introduced extension of the 2D Scale-Invariant Feature Transform (SIFT) framework1 to 3D.2 The SIFT feature extractor locates minima and maxima in the difference of Gaussian scale space to find salient feature points. It then uses histograms of the local gradient directions around each found extremum in 3D to characterize them in a 4096 element feature vector. Matching points are found by comparing the distance between feature vectors. We apply this method to the rigid registration of optic nerve head- (ONH) and macula-centered 3D OCT scans of the same patient that have only limited overlap. Three OCT data set pairs with known deformation were used for quantitative assessment of the method's robustness and accuracy when deformations of rotation and scaling were considered. Three-dimensional registration accuracy of 2.0+/-3.3 voxels was observed. The accuracy was assessed as average voxel distance error in N=1572 matched locations. The registration method was applied to 12 3D OCT scans (200 x 200 x 1024 voxels) of 6 normal eyes imaged in vivo to demonstrate the clinical utility and robustness of the method in a real-world environment.

  15. Surface driven biomechanical breast image registration

    NASA Astrophysics Data System (ADS)

    Eiben, Björn; Vavourakis, Vasileios; Hipwell, John H.; Kabus, Sven; Lorenz, Cristian; Buelow, Thomas; Williams, Norman R.; Keshtgar, M.; Hawkes, David J.

    2016-03-01

    Biomechanical modelling enables large deformation simulations of breast tissues under different loading conditions to be performed. Such simulations can be utilised to transform prone Magnetic Resonance (MR) images into a different patient position, such as upright or supine. We present a novel integration of biomechanical modelling with a surface registration algorithm which optimises the unknown material parameters of a biomechanical model and performs a subsequent regularised surface alignment. This allows deformations induced by effects other than gravity, such as those due to contact of the breast and MR coil, to be reversed. Correction displacements are applied to the biomechanical model enabling transformation of the original pre-surgical images to the corresponding target position. The algorithm is evaluated for the prone-to-supine case using prone MR images and the skin outline of supine Computed Tomography (CT) scans for three patients. A mean target registration error (TRE) of 10:9 mm for internal structures is achieved. For the prone-to-upright scenario, an optical 3D surface scan of one patient is used as a registration target and the nipple distances after alignment between the transformed MRI and the surface are 10:1 mm and 6:3 mm respectively.

  16. Comparison of carina-based versus bony anatomy-based registration for setup verification in esophageal cancer radiotherapy.

    PubMed

    Machiels, Mélanie; Jin, Peng; van Gurp, Christianne H; van Hooft, Jeanin E; Alderliesten, Tanja; Hulshof, Maarten C C M

    2018-03-21

    To investigate the feasibility and geometric accuracy of carina-based registration for CBCT-guided setup verification in esophageal cancer IGRT, compared with current practice bony anatomy-based registration. Included were 24 esophageal cancer patients with 65 implanted fiducial markers, visible on planning CTs and follow-up CBCTs. All available CBCT scans (n = 236) were rigidly registered to the planning CT with respect to the bony anatomy and the carina. Target coverage was visually inspected and marker position variation was quantified relative to both registration approaches; the variation of systematic (Σ) and random errors (σ) was estimated. Automatic carina-based registration was feasible in 94.9% of the CBCT scans, with an adequate target coverage in 91.1% compared to 100% after bony anatomy-based registration. Overall, Σ (σ) in the LR/CC/AP direction was 2.9(2.4)/4.1(2.4)/2.2(1.8) mm using the bony anatomy registration compared to 3.3(3.0)/3.6(2.6)/3.9(3.1) mm for the carina. Mid-thoracic placed markers showed a non-significant but smaller Σ in CC and AP direction when using the carina-based registration. Compared with a bony anatomy-based registration, carina-based registration for esophageal cancer IGRT results in inadequate target coverage in 8.9% of cases. Furthermore, large Σ and σ, requiring larger anisotropic margins, were seen after carina-based registration. Only for tumors entirely confined to the mid-thoracic region the carina-based registration might be slightly favorable.

  17. 78 FR 23595 - Importer of Controlled Substances; Notice of Registration; GE Healthcare

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-19

    ... Registration; GE Healthcare By Notice dated January 31, 2013, and published in the Federal Register on February 6, 2013, 78 FR 8583, GE Healthcare, 3350 North Ridge Avenue, Arlington Heights, Illinois 60004-1412... considered the factors in 21 U.S.C. 823(a) and 952(a) and determined that the registration of GE Healthcare...

  18. Coarse Point Cloud Registration by Egi Matching of Voxel Clusters

    NASA Astrophysics Data System (ADS)

    Wang, Jinhu; Lindenbergh, Roderik; Shen, Yueqian; Menenti, Massimo

    2016-06-01

    Laser scanning samples the surface geometry of objects efficiently and records versatile information as point clouds. However, often more scans are required to fully cover a scene. Therefore, a registration step is required that transforms the different scans into a common coordinate system. The registration of point clouds is usually conducted in two steps, i.e. coarse registration followed by fine registration. In this study an automatic marker-free coarse registration method for pair-wise scans is presented. First the two input point clouds are re-sampled as voxels and dimensionality features of the voxels are determined by principal component analysis (PCA). Then voxel cells with the same dimensionality are clustered. Next, the Extended Gaussian Image (EGI) descriptor of those voxel clusters are constructed using significant eigenvectors of each voxel in the cluster. Correspondences between clusters in source and target data are obtained according to the similarity between their EGI descriptors. The random sampling consensus (RANSAC) algorithm is employed to remove outlying correspondences until a coarse alignment is obtained. If necessary, a fine registration is performed in a final step. This new method is illustrated on scan data sampling two indoor scenarios. The results of the tests are evaluated by computing the point to point distance between the two input point clouds. The presented two tests resulted in mean distances of 7.6 mm and 9.5 mm respectively, which are adequate for fine registration.

  19. 21 CFR 1301.36 - Suspension or revocation of registration; suspension of registration pending final order...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Suspension or revocation of registration... Section 1301.36 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE REGISTRATION OF MANUFACTURERS, DISTRIBUTORS, AND DISPENSERS OF CONTROLLED SUBSTANCES Action on Application for Registration...

  20. A quality analysis of clinical anaesthesia study protocols from the Chinese clinical trials registry according to the SPIRIT statement

    PubMed Central

    Yang, Lei; Chen, Shouming; Yang, Di; Li, Jiajin; Wu, Taixiang; Zuo, Yunxia

    2018-01-01

    Objective To learn about the overall quality of clinical anaesthesia study protocols from the Chinese Clinical Trials Registry and to discuss the way to improve study protocol quality. Methods We defined completeness of each sub-item in SPIRIT as N/A (not applicable) or with a score of 0, 1, or 2. For each protocol, we calculated the proportion of adequately reported items (score = 2 and N/A) and unreported items (score = 0). Protocol quality was determined according to the proportion of reported items, with values >50% indicating high quality. Protocol quality was determined according to the proportion of reported items. For each sub-item in SPIRIT, we calculated the adequately reported rate (percentage of all protocols with score 2 and NA on one sub-item) as well as the unreported rate (percentage of all protocols with score 0 on one sub-item). Results Total 126 study protocols were available for assessment. Among these, 88.1% were assessed as being of low quality. By comparison, the percentage of low-quality protocols was 88.9% after the publication of the SPIRIT statement. Among the 51 SPIRIT sub-items, 18 sub-items had an unreported rate above 90% while 16 had a higher adequately reported rate than an unreported rate. Conclusions The overall quality of clinical anaesthesia study protocols registered in the ChiCTR was poor. A mandatory protocol upload and self-check based on the SPIRIT statement during the trial registration process may improve protocol quality in the future. PMID:29872509

  1. Position Statements, Issue Briefs, Resolutions and Consensus Statements. Revised

    ERIC Educational Resources Information Center

    National Association of School Nurses (NJ1), 2012

    2012-01-01

    This article presents position statements, issue briefs, and resolutions and consensus statements of the National Association of School Nurses (NASN). The Position Statements include: (1) Allergy/Anaphylaxis Management in the School Setting; (2) Caseload Assignments; (3) Child Mortality in the School Setting; (4) Chronic Health Conditions, Managed…

  2. 75 FR 40825 - Clofencet; Cancellation Order for Certain Pesticide Registrations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-14

    ... Monsanto Company to voluntarily cancel all these product registrations. These are the last products... Company Number Company Name and Address 524 Monsanto Company 1300 I Street N.W. Suite 450 Washington, DC...

  3. 40 CFR 79.23 - Registration.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... OF FUELS AND FUEL ADDITIVES Additive Registration Procedures § 79.23 Registration. (a) If the... additive which includes all of the information and assurances required by § 79.21 and has satisfactorily... the fuel additive and notify the fuel manufacturer of such registration. (b) The Administrator shall...

  4. 40 CFR 79.23 - Registration.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... OF FUELS AND FUEL ADDITIVES Additive Registration Procedures § 79.23 Registration. (a) If the... additive which includes all of the information and assurances required by § 79.21 and has satisfactorily... the fuel additive and notify the fuel manufacturer of such registration. (b) The Administrator shall...

  5. 40 CFR 79.23 - Registration.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... OF FUELS AND FUEL ADDITIVES Additive Registration Procedures § 79.23 Registration. (a) If the... additive which includes all of the information and assurances required by § 79.21 and has satisfactorily... the fuel additive and notify the fuel manufacturer of such registration. (b) The Administrator shall...

  6. 40 CFR 79.23 - Registration.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... OF FUELS AND FUEL ADDITIVES Additive Registration Procedures § 79.23 Registration. (a) If the... additive which includes all of the information and assurances required by § 79.21 and has satisfactorily... the fuel additive and notify the fuel manufacturer of such registration. (b) The Administrator shall...

  7. 40 CFR 79.23 - Registration.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... OF FUELS AND FUEL ADDITIVES Additive Registration Procedures § 79.23 Registration. (a) If the... additive which includes all of the information and assurances required by § 79.21 and has satisfactorily... the fuel additive and notify the fuel manufacturer of such registration. (b) The Administrator shall...

  8. Automated Registration of Multimodal Optic Disc Images: Clinical Assessment of Alignment Accuracy.

    PubMed

    Ng, Wai Siene; Legg, Phil; Avadhanam, Venkat; Aye, Kyaw; Evans, Steffan H P; North, Rachel V; Marshall, Andrew D; Rosin, Paul; Morgan, James E

    2016-04-01

    To determine the accuracy of automated alignment algorithms for the registration of optic disc images obtained by 2 different modalities: fundus photography and scanning laser tomography. Images obtained with the Heidelberg Retina Tomograph II and paired photographic optic disc images of 135 eyes were analyzed. Three state-of-the-art automated registration techniques Regional Mutual Information, rigid Feature Neighbourhood Mutual Information (FNMI), and nonrigid FNMI (NRFNMI) were used to align these image pairs. Alignment of each composite picture was assessed on a 5-point grading scale: "Fail" (no alignment of vessels with no vessel contact), "Weak" (vessels have slight contact), "Good" (vessels with <50% contact), "Very Good" (vessels with >50% contact), and "Excellent" (complete alignment). Custom software generated an image mosaic in which the modalities were interleaved as a series of alternate 5×5-pixel blocks. These were graded independently by 3 clinically experienced observers. A total of 810 image pairs were assessed. All 3 registration techniques achieved a score of "Good" or better in >95% of the image sets. NRFNMI had the highest percentage of "Excellent" (mean: 99.6%; range, 95.2% to 99.6%), followed by Regional Mutual Information (mean: 81.6%; range, 86.3% to 78.5%) and FNMI (mean: 73.1%; range, 85.2% to 54.4%). Automated registration of optic disc images by different modalities is a feasible option for clinical application. All 3 methods provided useful levels of alignment, but the NRFNMI technique consistently outperformed the others and is recommended as a practical approach to the automated registration of multimodal disc images.

  9. Multimodal Image Registration through Simultaneous Segmentation.

    PubMed

    Aganj, Iman; Fischl, Bruce

    2017-11-01

    Multimodal image registration facilitates the combination of complementary information from images acquired with different modalities. Most existing methods require computation of the joint histogram of the images, while some perform joint segmentation and registration in alternate iterations. In this work, we introduce a new non-information-theoretical method for pairwise multimodal image registration, in which the error of segmentation - using both images - is considered as the registration cost function. We empirically evaluate our method via rigid registration of multi-contrast brain magnetic resonance images, and demonstrate an often higher registration accuracy in the results produced by the proposed technique, compared to those by several existing methods.

  10. 32 CFR 1615.6 - Selective service number.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 6 2011-07-01 2011-07-01 false Selective service number. 1615.6 Section 1615.6... REGISTRATION § 1615.6 Selective service number. Every registrant shall be given a selective service number. The Social Security Account Number will not be used for this purpose. ...

  11. 77 FR 38016 - Proposed Policy Clarification for the Registration of Aircraft to U.S. Citizen Trustees in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-26

    ...-0658] Proposed Policy Clarification for the Registration of Aircraft to U.S. Citizen Trustees in... regarding the registration of aircraft to U.S. Citizen Trustees in situations involving Non-U.S. citizen... Administration (FAA) on Wednesday, June 6, 2012, in Oklahoma City, Oklahoma, concerning aircraft registration by...

  12. Development and application of pulmonary structure-function registration methods: towards pulmonary image-guidance tools for improved airway targeted therapies and outcomes

    NASA Astrophysics Data System (ADS)

    Guo, Fumin; Pike, Damien; Svenningsen, Sarah; Coxson, Harvey O.; Drozd, John J.; Yuan, Jing; Fenster, Aaron; Parraga, Grace

    2014-03-01

    Objectives: We aimed to develop a way to rapidly generate multi-modality (MRI-CT) pulmonary imaging structurefunction maps using novel non-rigid image registration methods. This objective is part of our overarching goal to provide an image processing pipeline to generate pulmonary structure-function maps and guide airway-targeted therapies. Methods: Anatomical 1H and functional 3He MRI were acquired in 5 healthy asymptomatic ex-smokers and 7 ex-smokers with chronic obstructive pulmonary disease (COPD) at inspiration breath-hold. Thoracic CT was performed within ten minutes of MRI using the same breath-hold volume. Landmark-based affine registration methods previously validated for imaging of COPD, was based on corresponding fiducial markers located in both CT and 1H MRI coronal slices and compared with shape-based CT-MRI non-rigid registration. Shape-based CT-MRI registration was developed by first identifying the shapes of the lung cavities manually, and then registering the two shapes using affine and thin-plate spline algorithms. We compared registration accuracy using the fiducial localization error (FLE) and target registration error (TRE). Results: For landmark-based registration, the TRE was 8.4±5.3 mm for whole lung and 7.8±4.6 mm for the R and L lungs registered independently (p=0.4). For shape-based registration, the TRE was 8.0±4.6 mm for whole lung as compared to 6.9±4.4 mm for the R and L lung registered independently and this difference was significant (p=0.01). The difference for shape-based (6.9±4.4 mm) and landmark-based R and L lung registration (7.8±4.6 mm) was also significant (p=.04) Conclusion: Shape-based registration TRE was significantly improved compared to landmark-based registration when considering L and R lungs independently.

  13. The hidden KPI registration accuracy.

    PubMed

    Shorrosh, Paul

    2011-09-01

    Determining the registration accuracy rate is fundamental to improving revenue cycle key performance indicators. A registration quality assurance (QA) process allows errors to be corrected before bills are sent and helps registrars learn from their mistakes. Tools are available to help patient access staff who perform registration QA manually.

  14. Feature-based US to CT registration of the aortic root

    NASA Astrophysics Data System (ADS)

    Lang, Pencilla; Chen, Elvis C. S.; Guiraudon, Gerard M.; Jones, Doug L.; Bainbridge, Daniel; Chu, Michael W.; Drangova, Maria; Hata, Noby; Jain, Ameet; Peters, Terry M.

    2011-03-01

    A feature-based registration was developed to align biplane and tracked ultrasound images of the aortic root with a preoperative CT volume. In transcatheter aortic valve replacement, a prosthetic valve is inserted into the aortic annulus via a catheter. Poor anatomical visualization of the aortic root region can result in incorrect positioning, leading to significant morbidity and mortality. Registration of pre-operative CT to transesophageal ultrasound and fluoroscopy images is a major step towards providing augmented image guidance for this procedure. The proposed registration approach uses an iterative closest point algorithm to register a surface mesh generated from CT to 3D US points reconstructed from a single biplane US acquisition, or multiple tracked US images. The use of a single simultaneous acquisition biplane image eliminates reconstruction error introduced by cardiac gating and TEE probe tracking, creating potential for real-time intra-operative registration. A simple initialization procedure is used to minimize changes to operating room workflow. The algorithm is tested on images acquired from excised porcine hearts. Results demonstrate a clinically acceptable accuracy of 2.6mm and 5mm for tracked US to CT and biplane US to CT registration respectively.

  15. 14 CFR 47.16 - Temporary registration numbers.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AIRCRAFT REGISTRATION General § 47.16 Temporary registration numbers. (a) Temporary registration numbers... Registration Certificates for temporary display on aircraft during flight allowed under Subpart C of this part. (b) The holder of a Dealer's Aircraft Registration Certificate may apply to the FAA Aircraft Registry...

  16. 12 CFR 583.18 - Registrant.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Registrant. 583.18 Section 583.18 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY DEFINITIONS FOR REGULATIONS AFFECTING SAVINGS AND LOAN HOLDING COMPANIES § 583.18 Registrant. The term registrant means a savings and loan...

  17. 78 FR 63977 - Environmental Impact Statements; Notice of Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-25

    ... ENVIRONMENTAL PROTECTION AGENCY [ER-FRL-9011-6] Environmental Impact Statements; Notice of Availability Responsible Agency: Office of Federal Activities, General Information (202) 564-7146 or http://www.epa.gov/compliance/nepa/ . Weekly receipt of Environmental Impact Statements Filed 09/30/2013 Through 10/18/2013 Pursuant to 40 CFR 1506.9....

  18. 21 CFR 501.17 - Animal food labeling warning statements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 6 2014-04-01 2014-04-01 false Animal food labeling warning statements. 501.17... food labeling warning statements. (a) Self-pressurized containers. (1) The label of a food packaged in... the following warning: Warning Avoid spraying in eyes. Contents under pressure. Do not puncture or...

  19. Pesticide Registration Information System

    EPA Pesticide Factsheets

    PRISM provides an integrated, web portal for all pesticide related data, communications, registrations and transactions for OPP and its stakeholders, partners and customers. PRISM supports Strategic Goal 4 by automating pesticide registration processes.

  20. Effects of government registration on unprotected sex among female sex workers in Tijuana, Mexico

    PubMed Central

    Sirotin, Nicole; Strathdee, Steffanie A.; Lozada, Remedios; Abramovitz, Daniela; Semple, Shirley J.; Bucardo, Jesús; Patterson, Thomas L.

    2010-01-01

    Background Sex work is partially regulated in Tijuana, but little is known of its health effects. A recent behavioral intervention among female sex workers (FSWs) decreased incidence of HIV/STIs by 40%. We evaluated effects of sex worker regulation on condom use among FSWs randomized to this intervention. Methods FSWs aged ≥18 years who reported unprotected sex with ≥1 client in the last 2 months and whether they were registered with Tijuana’s Municipal Health Department underwent a brief, theory-based behavioral intervention to increase condom use. At baseline and 6 months, women underwent interviews and testing for HIV, syphilis, C. trachomatis and N. gonorrhoeae. Negative binomial regression was used to determine the effect of registration on numbers of unprotected sex acts and cumulative HIV/STI incidence. Results Of 187 women, 83 (44%) were registered. Lack of registration was associated with higher rates of unprotected sex (rate ratio: 1.7, 95% CI: 1.2–2.3), compared to FSWs who were registered, after controlling for potential confounders. Conclusions Registration predicted increased condom use among FSWs enrolled in a behavioral intervention. Public health programs designed to improve condom use among FSWs may benefit from understanding the impact of existing regulation systems on HIV risk behaviors. PMID:20956076

  1. 14 CFR 47.3 - Registration required.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... REGISTRATION General § 47.3 Registration required. (a) An aircraft may be registered under 49 U.S.C. 44103 only... person may operate an aircraft that is eligible for registration under 49 U.S.C. 44101-44104, unless the... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Registration required. 47.3 Section 47.3...

  2. 14 CFR 47.3 - Registration required.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... REGISTRATION General § 47.3 Registration required. (a) An aircraft may be registered under 49 U.S.C. 44103 only... person may operate an aircraft that is eligible for registration under 49 U.S.C. 44101-44104, unless the... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Registration required. 47.3 Section 47.3...

  3. 14 CFR 47.3 - Registration required.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... REGISTRATION General § 47.3 Registration required. (a) An aircraft may be registered under 49 U.S.C. 44103 only... eligible for registration under 49 U.S.C. 44101-44104, unless the aircraft— (1) Has been registered by its... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Registration required. 47.3 Section 47.3...

  4. 14 CFR 47.3 - Registration required.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... REGISTRATION General § 47.3 Registration required. (a) An aircraft may be registered under 49 U.S.C. 44103 only... person may operate an aircraft that is eligible for registration under 49 U.S.C. 44101-44104, unless the... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Registration required. 47.3 Section 47.3...

  5. 14 CFR 47.3 - Registration required.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... REGISTRATION General § 47.3 Registration required. (a) An aircraft may be registered under 49 U.S.C. 44103 only... person may operate an aircraft that is eligible for registration under 49 U.S.C. 44101-44104, unless the... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Registration required. 47.3 Section 47.3...

  6. Novel α-Oxoamide Advanced-Glycation Endproducts within the N6-Carboxymethyl Lysine and N6-Carboxyethyl Lysine Reaction Cascades.

    PubMed

    Baldensperger, Tim; Jost, Tobias; Zipprich, Alexander; Glomb, Marcus A

    2018-02-28

    The highly reactive α-dicarbonyl compounds glyoxal and methylglyoxal are major precursors of posttranslational protein modifications in vivo. Model incubations of N 2 -t-Boc-lysine and either glyoxal or methylglyoxal were used to further elucidate the underlying mechanisms of the N 6 -carboxymethyl lysine and N 6 -carboxyethyl lysine reaction cascades. After independent synthesis of the authentic reference standards, we were able to detect N 6 -glyoxylyl lysine and N 6 -pyruvoyl lysine for the first time by HPLC-MS 2 analyses. These two novel amide advanced-glycation endproducts were exclusively formed under aerated conditions, suggesting that they were potent markers for oxidative stress. Analogous to the well-known Strecker degradation pathway, leading from amino acids to Strecker acids, the oxidation of an enaminol intermediate is suggested to be the key mechanistic step. A highly sensitive workup for the determination of AGEs in tissues was developed. In support of our hypothesis, the levels of N 6 -glyoxylyl lysine and N 6 -pyruvoyl lysine in rat livers indeed correlated with liver cirrhosis and aging.

  7. 40 CFR 152.135 - Transfer of registration.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... wishes to transfer data rights at the same time as he transfers the registration, he may submit a single... 40 Protection of Environment 24 2011-07-01 2011-07-01 false Transfer of registration. 152.135... Transfer of registration. (a) A registrant may transfer the registration of a product to another person...

  8. 40 CFR 152.135 - Transfer of registration.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... wishes to transfer data rights at the same time as he transfers the registration, he may submit a single... 40 Protection of Environment 24 2014-07-01 2014-07-01 false Transfer of registration. 152.135... Transfer of registration. (a) A registrant may transfer the registration of a product to another person...

  9. 32 CFR 1630.47 - Class 4-W: Registrant who has completed alternative service in lieu of induction.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Class 4-W: Registrant who has completed... to National Defense SELECTIVE SERVICE SYSTEM CLASSIFICATION RULES § 1630.47 Class 4-W: Registrant who has completed alternative service in lieu of induction. In Class 4-W shall be placed any registrant...

  10. 3D-2D registration for surgical guidance: effect of projection view angles on registration accuracy

    NASA Astrophysics Data System (ADS)

    Uneri, A.; Otake, Y.; Wang, A. S.; Kleinszig, G.; Vogt, S.; Khanna, A. J.; Siewerdsen, J. H.

    2014-01-01

    An algorithm for intensity-based 3D-2D registration of CT and x-ray projections is evaluated, specifically using single- or dual-projection views to provide 3D localization. The registration framework employs the gradient information similarity metric and covariance matrix adaptation evolution strategy to solve for the patient pose in six degrees of freedom. Registration performance was evaluated in an anthropomorphic phantom and cadaver, using C-arm projection views acquired at angular separation, Δθ, ranging from ˜0°-180° at variable C-arm magnification. Registration accuracy was assessed in terms of 2D projection distance error and 3D target registration error (TRE) and compared to that of an electromagnetic (EM) tracker. The results indicate that angular separation as small as Δθ ˜10°-20° achieved TRE <2 mm with 95% confidence, comparable or superior to that of the EM tracker. The method allows direct registration of preoperative CT and planning data to intraoperative fluoroscopy, providing 3D localization free from conventional limitations associated with external fiducial markers, stereotactic frames, trackers and manual registration.

  11. Registration practices for observational studies on ClinicalTrials.gov indicated low adherence.

    PubMed

    Boccia, Stefania; Rothman, Kenneth J; Panic, Nikola; Flacco, Maria Elena; Rosso, Annalisa; Pastorino, Roberta; Manzoli, Lamberto; La Vecchia, Carlo; Villari, Paolo; Boffetta, Paolo; Ricciardi, Walter; Ioannidis, John P A

    2016-02-01

    The study aims to assess the status of registration of observational studies. We identified studies on cancer research with prospective recruitment of participants that were registered from February 2000 to December 2011 in ClinicalTrials.gov. We recorded the dates of registration and start of recruitment, outcomes, and description of statistical method. We searched for publications corresponding to the registered studies through May 31, 2014. One thousand one hundred nine registered studies were eligible. Primary and secondary outcomes were reported in 809 (73.0%) and 464 (41.8%) of them. The date of registration preceded the month of the study start in 145 (13.8%) and coincided in 205 (19.5%). A total of 151 publications from 120 (10.8%) registered studies were identified. In 2 (33.3%) of the 6 publications where ClinicalTrials.gov reported that the study started recruitment after registration, and in 9 (50.0%) of 18 publications where ClinicalTrials.gov reported the same date for registration and start of recruitment, the articles showed that the study had actually started recruiting before registration. During the period reviewed, few observational studies have been registered. Registration usually occurred after the study started, and prespecification of outcomes and statistical analysis rarely occurred. Copyright © 2016 Elsevier Inc. All rights reserved.

  12. 22 CFR 122.3 - Registration fees.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... registration. (4) For registrants, including universities, exempt from income taxation pursuant to 26 U.S.C... eligible, the registrant and all of its subsidiaries/affiliates must be exempt from income taxation...

  13. 49 CFR 520.28 - Preparation of final environmental impact statements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 6 2010-10-01 2010-10-01 false Preparation of final environmental impact... ENVIRONMENTAL IMPACTS Procedures § 520.28 Preparation of final environmental impact statements. (a) If the... for the action shall prepare a final environmental impact statement (FEIS), taking into account all...

  14. 32 CFR 1636.6 - Analysis of belief.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 6 2013-07-01 2013-07-01 false Analysis of belief. 1636.6 Section 1636.6... CONSCIENTIOUS OBJECTORS § 1636.6 Analysis of belief. (a) A registrant claiming conscientious objection is not... group opposed to participation in war in any form. (b) The registrant who identifies his beliefs with...

  15. 32 CFR 1636.6 - Analysis of belief.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 6 2012-07-01 2012-07-01 false Analysis of belief. 1636.6 Section 1636.6... CONSCIENTIOUS OBJECTORS § 1636.6 Analysis of belief. (a) A registrant claiming conscientious objection is not... group opposed to participation in war in any form. (b) The registrant who identifies his beliefs with...

  16. 32 CFR 1636.6 - Analysis of belief.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 6 2014-07-01 2014-07-01 false Analysis of belief. 1636.6 Section 1636.6... CONSCIENTIOUS OBJECTORS § 1636.6 Analysis of belief. (a) A registrant claiming conscientious objection is not... group opposed to participation in war in any form. (b) The registrant who identifies his beliefs with...

  17. 32 CFR 1636.6 - Analysis of belief.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Analysis of belief. 1636.6 Section 1636.6... CONSCIENTIOUS OBJECTORS § 1636.6 Analysis of belief. (a) A registrant claiming conscientious objection is not... group opposed to participation in war in any form. (b) The registrant who identifies his beliefs with...

  18. 32 CFR 1636.6 - Analysis of belief.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 6 2011-07-01 2011-07-01 false Analysis of belief. 1636.6 Section 1636.6... CONSCIENTIOUS OBJECTORS § 1636.6 Analysis of belief. (a) A registrant claiming conscientious objection is not... group opposed to participation in war in any form. (b) The registrant who identifies his beliefs with...

  19. Registration Documents for Enlist Duo Herbicide (2014)

    EPA Pesticide Factsheets

    See details of the registration of Enlist Duo in 2014, including the notification to the registrant, the details of the assessment and registration decision, and the response to public comment on the proposed registration.

  20. Effect of iris registration on outcomes of FEMTOLASIK for myopia and myopic astigmatism.

    PubMed

    Ghoreishi, Mohammad; Beni, Zahra Naderi; Beni, Afsaneh Naderi; Kianersi, Farzan

    2017-09-05

    To compare the visual and refractive outcomes after FEMTOLASIK with and without iris registration. In this randomized, prospective, comparative, contralateral eye study, 118 eyes of 59 patients with myopia and myopic astigmatism underwent LASIK using the Femto LDV femtosecond laser (160 µm) and the MEL80 with or without iris registration. For each patient, iris registration FEMTOLASIK was performed on one eye and non-iris registration FEMTOLASIK was performed on the other eye, assigned at random. Patients were evaluated before and 12 months. Uncorrected visual acuity, best-corrected visual acuity, manifest refraction, contrast sensitivity, and higher-order aberrations (HOAs) were evaluated. At 12 months, the mean UDVA was 0.002 ± 0.07 logMAR (20/19) in iris registration eyes and 0.00 ± 0.06 logMAR (20/24) in non-iris registration eyes (P = 0.9). 61% of iris registration eyes and 71.2% of non-iris registration eyes achieved a UDVA of 20/20 or better (P = 0.31); 98.3% of eyes with the iris registration FEMTOLASIK and 94.9% with the non-iris registration FEMTOLASIK were within ±0.50 D from emmetropia (P = 0.71). No statistically significant difference was found in postoperative contrast sensitivity between groups at 3, 6, 12, or 18 cycles/degree (P > 0.05). There was significant increase in total HOA root mean square in two groups. The mean error magnitude of surgically induced astigmatism 12 months postoperatively was -0.33 in iris registration eyes and -0.24 in the non-iris registration eyes (P = 0.36). FEMTOLASIK with and without iris registration provides similar results in myopic and myopic astigmatism patients.

  1. 32 CFR 1645.9 - Statement of reason for denial.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Statement of reason for denial. 1645.9 Section 1645.9 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM CLASSIFICATION OF MINISTERS OF RELIGION § 1645.9 Statement of reason for denial. (a) Denial of a 4-D claim by a...

  2. 32 CFR 1645.9 - Statement of reason for denial.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 6 2012-07-01 2012-07-01 false Statement of reason for denial. 1645.9 Section 1645.9 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM CLASSIFICATION OF MINISTERS OF RELIGION § 1645.9 Statement of reason for denial. (a) Denial of a 4-D claim by a...

  3. 32 CFR 1645.9 - Statement of reason for denial.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 6 2011-07-01 2011-07-01 false Statement of reason for denial. 1645.9 Section 1645.9 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM CLASSIFICATION OF MINISTERS OF RELIGION § 1645.9 Statement of reason for denial. (a) Denial of a 4-D claim by a...

  4. 32 CFR 1645.9 - Statement of reason for denial.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 6 2013-07-01 2013-07-01 false Statement of reason for denial. 1645.9 Section 1645.9 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM CLASSIFICATION OF MINISTERS OF RELIGION § 1645.9 Statement of reason for denial. (a) Denial of a 4-D claim by a...

  5. 32 CFR 1645.9 - Statement of reason for denial.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 6 2014-07-01 2014-07-01 false Statement of reason for denial. 1645.9 Section 1645.9 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM CLASSIFICATION OF MINISTERS OF RELIGION § 1645.9 Statement of reason for denial. (a) Denial of a 4-D claim by a...

  6. Public Participation Process for Registration Actions

    EPA Pesticide Factsheets

    Describes the process for registration actions which provides the opportunity for the public to comment on major registration decisions at a point in the registration process when comprehensive information and analysis are available.

  7. ACHP | ACHP Policy Statements

    Science.gov Websites

    Search skip specific nav links Home arrow The National Historic Preservation Program arrow ACHP Policy Statements ACHP Policy Statements ACHP Policy Statement on Controversial Commemorative Works ACHP Policy Statement on Historic Preservation and Community Revitalizations Policy Statement on the ACHP's Interaction

  8. Predictors of support for juvenile sex offender registration: educated individuals recognize the flaws of juvenile registration.

    PubMed

    Stevenson, Margaret C; Smith, Amy C; Sekely, Ady; Farnum, Katlyn S

    2013-01-01

    We investigated demographic predictors of support for juvenile sex offender registration policies, including education level, gender, political orientation, and age. Participants were 168 individuals recruited from public places in a Midwest community (45% women; M age = 42). In line with hypotheses, as education level increased, support for juvenile registration decreased, as did the belief that juvenile registration protects the community. In addition, as education level increased, belief that the juvenile understood his actions decreased, as did support for juvenile registration when it is framed as ineffective at reducing sex crime. These beliefs mediated the relationship between education level and diminished support for juvenile registration. Implications of these results for the advancement of effective juvenile sex offender policy are discussed.

  9. Mammogram registration: a phantom-based evaluation of compressed breast thickness variation effects.

    PubMed

    Richard, Frédéric J P; Bakić, Predrag R; Maidment, Andrew D A

    2006-02-01

    The temporal comparison of mammograms is complex; a wide variety of factors can cause changes in image appearance. Mammogram registration is proposed as a method to reduce the effects of these changes and potentially to emphasize genuine alterations in breast tissue. Evaluation of such registration techniques is difficult since ground truth regarding breast deformations is not available in clinical mammograms. In this paper, we propose a systematic approach to evaluate sensitivity of registration methods to various types of changes in mammograms using synthetic breast images with known deformations. As a first step, images of the same simulated breasts with various amounts of simulated physical compression have been used to evaluate a previously described nonrigid mammogram registration technique. Registration performance is measured by calculating the average displacement error over a set of evaluation points identified in mammogram pairs. Applying appropriate thickness compensation and using a preferred order of the registered images, we obtained an average displacement error of 1.6 mm for mammograms with compression differences of 1-3 cm. The proposed methodology is applicable to analysis of other sources of mammogram differences and can be extended to the registration of multimodality breast data.

  10. High-Frequency Mapping of the IPV6 Internet Using YARRP

    DTIC Science & Technology

    2017-03-01

    NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA APPLIED CYBER OPERATIONS CAPSTONE PROJECT REPORT HIGH -FREQUENCY MAPPING OF THE IPV6 INTERNET USING...03-30-2017 4. TITLE AND SUBTITLE HIGH -FREQUENCY MAPPING OF THE IPV6 INTERNET USING YARRP 5. FUNDING NUMBERS RCKHX 6. AUTHOR(S) Eric W. Gaston 7...the U.S. Government. IRB Protocol Number: N/A. 12a. DISTRIBUTION / AVAILABILITY STATEMENT Approved for public release. Distribution is unlimited. 12b

  11. 32 CFR 806b.11 - When to give Privacy Act Statements (PAS).

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 6 2011-07-01 2011-07-01 false When to give Privacy Act Statements (PAS). 806b... ADMINISTRATION PRIVACY ACT PROGRAM Collecting Personal Information § 806b.11 When to give Privacy Act Statements... information. Give a copy of the Privacy Act Statement if asked. Do not ask the person to sign the Privacy Act...

  12. 32 CFR 806b.11 - When to give Privacy Act Statements (PAS).

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 6 2013-07-01 2013-07-01 false When to give Privacy Act Statements (PAS). 806b... ADMINISTRATION PRIVACY ACT PROGRAM Collecting Personal Information § 806b.11 When to give Privacy Act Statements... information. Give a copy of the Privacy Act Statement if asked. Do not ask the person to sign the Privacy Act...

  13. 32 CFR 806b.11 - When to give Privacy Act Statements (PAS).

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false When to give Privacy Act Statements (PAS). 806b... ADMINISTRATION PRIVACY ACT PROGRAM Collecting Personal Information § 806b.11 When to give Privacy Act Statements... information. Give a copy of the Privacy Act Statement if asked. Do not ask the person to sign the Privacy Act...

  14. 14 CFR 47.39 - Effective date of registration.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... AIRCRAFT REGISTRATION Certificates of Aircraft Registration § 47.39 Effective date of registration. An... this part. The effective date of registration is shown by a date stamp on the Aircraft Registration Application, AC Form 8050-1, and as the date of issue on the Certificate of Aircraft Registration, AC Form...

  15. 14 CFR 47.39 - Effective date of registration.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... AIRCRAFT REGISTRATION Certificates of Aircraft Registration § 47.39 Effective date of registration. An... this part. The effective date of registration is shown by a date stamp on the Aircraft Registration Application, AC Form 8050-1, and as the date of issue on the Certificate of Aircraft Registration, AC Form...

  16. 14 CFR 47.39 - Effective date of registration.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... AIRCRAFT REGISTRATION Certificates of Aircraft Registration § 47.39 Effective date of registration. An... this part. The effective date of registration is shown by a date stamp on the Aircraft Registration Application, AC Form 8050-1, and as the date of issue on the Certificate of Aircraft Registration, AC Form...

  17. 14 CFR 47.39 - Effective date of registration.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... AIRCRAFT REGISTRATION Certificates of Aircraft Registration § 47.39 Effective date of registration. An... this part. The effective date of registration is shown by a date stamp on the Aircraft Registration Application, AC Form 8050-1, and as the date of issue on the Certificate of Aircraft Registration, AC Form...

  18. Evaluation of five diffeomorphic image registration algorithms for mouse brain magnetic resonance microscopy.

    PubMed

    Fu, Zhenrong; Lin, Lan; Tian, Miao; Wang, Jingxuan; Zhang, Baiwen; Chu, Pingping; Li, Shaowu; Pathan, Muhammad Mohsin; Deng, Yulin; Wu, Shuicai

    2017-11-01

    The development of genetically engineered mouse models for neuronal diseases and behavioural disorders have generated a growing need for small animal imaging. High-resolution magnetic resonance microscopy (MRM) provides powerful capabilities for noninvasive studies of mouse brains, while avoiding some limits associated with the histological procedures. Quantitative comparison of structural images is a critical step in brain imaging analysis, which highly relies on the performance of image registration techniques. Nowadays, there is a mushrooming growth of human brain registration algorithms, while fine-tuning of those algorithms for mouse brain MRMs is rarely addressed. Because of their topology preservation property and outstanding performance in human studies, diffeomorphic transformations have become popular in computational anatomy. In this study, we specially tuned five diffeomorphic image registration algorithms [DARTEL, geodesic shooting, diffeo-demons, SyN (Greedy-SyN and geodesic-SyN)] for mouse brain MRMs and evaluated their performance using three measures [volume overlap percentage (VOP), residual intensity error (RIE) and surface concordance ratio (SCR)]. Geodesic-SyN performed significantly better than the other methods according to all three different measures. These findings are important for the studies on structural brain changes that may occur in wild-type and transgenic mouse brains. © 2017 The Authors Journal of Microscopy © 2017 Royal Microscopical Society.

  19. 21 CFR 607.35 - Notification of registrant; blood product establishment registration number and NDC Labeler Code.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 7 2013-04-01 2013-04-01 false Notification of registrant; blood product... PRODUCT LISTING FOR MANUFACTURERS OF HUMAN BLOOD AND BLOOD PRODUCTS Procedures for Domestic Blood Product Establishments § 607.35 Notification of registrant; blood product establishment registration number and NDC...

  20. 21 CFR 607.35 - Notification of registrant; blood product establishment registration number and NDC Labeler Code.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 7 2012-04-01 2012-04-01 false Notification of registrant; blood product... PRODUCT LISTING FOR MANUFACTURERS OF HUMAN BLOOD AND BLOOD PRODUCTS Procedures for Domestic Blood Product Establishments § 607.35 Notification of registrant; blood product establishment registration number and NDC...

  1. 21 CFR 607.35 - Notification of registrant; blood product establishment registration number and NDC Labeler Code.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 7 2014-04-01 2014-04-01 false Notification of registrant; blood product... PRODUCT LISTING FOR MANUFACTURERS OF HUMAN BLOOD AND BLOOD PRODUCTS Procedures for Domestic Blood Product Establishments § 607.35 Notification of registrant; blood product establishment registration number and NDC...

  2. 32 CFR 1633.6 - Consideration of classes.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Consideration of classes. 1633.6 Section 1633.6... CLASSIFICATION § 1633.6 Consideration of classes. Claims of a registrant will be considered in inverse order of the listing of the classes below. When grounds are established to place a registrant in one or more of...

  3. A bronchoscopic navigation system using bronchoscope center calibration for accurate registration of electromagnetic tracker and CT volume without markers.

    PubMed

    Luo, Xiongbiao

    2014-06-01

    Various bronchoscopic navigation systems are developed for diagnosis, staging, and treatment of lung and bronchus cancers. To construct electromagnetically navigated bronchoscopy systems, registration of preoperative images and an electromagnetic tracker must be performed. This paper proposes a new marker-free registration method, which uses the centerlines of the bronchial tree and the center of a bronchoscope tip where an electromagnetic sensor is attached, to align preoperative images and electromagnetic tracker systems. The chest computed tomography (CT) volume (preoperative images) was segmented to extract the bronchial centerlines. An electromagnetic sensor was fixed at the bronchoscope tip surface. A model was designed and printed using a 3D printer to calibrate the relationship between the fixed sensor and the bronchoscope tip center. For each sensor measurement that includes sensor position and orientation information, its corresponding bronchoscope tip center position was calculated. By minimizing the distance between each bronchoscope tip center position and the bronchial centerlines, the spatial alignment of the electromagnetic tracker system and the CT volume was determined. After obtaining the spatial alignment, an electromagnetic navigation bronchoscopy system was established to real-timely track or locate a bronchoscope inside the bronchial tree during bronchoscopic examinations. The electromagnetic navigation bronchoscopy system was validated on a dynamic bronchial phantom that can simulate respiratory motion with a breath rate range of 0-10 min(-1). The fiducial and target registration errors of this navigation system were evaluated. The average fiducial registration error was reduced from 8.7 to 6.6 mm. The average target registration error, which indicates all tracked or navigated bronchoscope position accuracy, was much reduced from 6.8 to 4.5 mm compared to previous registration methods. An electromagnetically navigated bronchoscopy system was

  4. 3D Registration of mpMRI for Assessment of Prostate Cancer Focal Therapy.

    PubMed

    Orczyk, Clément; Rosenkrantz, Andrew B; Mikheev, Artem; Villers, Arnauld; Bernaudin, Myriam; Taneja, Samir S; Valable, Samuel; Rusinek, Henry

    2017-12-01

    This study aimed to assess a novel method of three-dimensional (3D) co-registration of prostate magnetic resonance imaging (MRI) examinations performed before and after prostate cancer focal therapy. We developed a software platform for automatic 3D deformable co-registration of prostate MRI at different time points and applied this method to 10 patients who underwent focal ablative therapy. MRI examinations were performed preoperatively, as well as 1 week and 6 months post treatment. Rigid registration served as reference for assessing co-registration accuracy and precision. Segmentation of preoperative and postoperative prostate revealed a significant postoperative volume decrease of the gland that averaged 6.49 cc (P = .017). Applying deformable transformation based on mutual information from 120 pairs of MRI slices, we refined by 2.9 mm (max. 6.25 mm) the alignment of the ablation zone, segmented from contrast-enhanced images on the 1-week postoperative examination, to the 6-month postoperative T2-weighted images. This represented a 500% improvement over the rigid approach (P = .001), corrected by volume. The dissimilarity by Dice index of the mapped ablation zone using deformable transformation vs rigid control was significantly (P = .04) higher at the ablation site than in the whole gland. Our findings illustrate our method's ability to correct for deformation at the ablation site. The preliminary analysis suggests that deformable transformation computed from mutual information of preoperative and follow-up MRI is accurate in co-registration of MRI examinations performed before and after focal therapy. The ability to localize the previously ablated tissue in 3D space may improve targeting for image-guided follow-up biopsy within focal therapy protocols. Copyright © 2017 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.

  5. Internal Users and Uses of Financial Statements within the Federal Government

    DTIC Science & Technology

    2012-06-01

    income statement, a statement of cash flows, and a statement of changes in stockholders’ equity. The uses and users of private-sector financial...financial reports to identify issues of risk and opportunities based upon 6 significant year-to-year changes, long term liabilities or cash position, or...for the first time (i.e., reconciling cash with the Treasury’s balance) and has constructed an effective audit response infrastructure “enabling the

  6. Clinical trial registration in oral health journals.

    PubMed

    Smaïl-Faugeron, V; Fron-Chabouis, H; Durieux, P

    2015-03-01

    Prospective registration of randomized controlled trials (RCTs) represents the best solution to reporting bias. The extent to which oral health journals have endorsed and complied with RCT registration is unknown. We identified journals publishing RCTs in dentistry, oral surgery, and medicine in the Journal Citation Reports. We classified journals into 3 groups: journals requiring or recommending trial registration, journals referring indirectly to registration, and journals providing no reference to registration. For the 5 journals with the highest 2012 impact factors in each group, we assessed whether RCTs with results published in 2013 had been registered. Of 78 journals examined, 32 (41%) required or recommended trial registration, 19 (24%) referred indirectly to registration, and 27 (35%) provided no reference to registration. We identified 317 RCTs with results published in the 15 selected journals in 2013. Overall, 73 (23%) were registered in a trial registry. Among those, 91% were registered retrospectively and 32% did not report trial registration in the published article. The proportion of trials registered was not significantly associated with editorial policies: 29% with results in journals that required or recommended registration, 15% in those that referred indirectly to registration, and 21% in those providing no reference to registration (P = 0.05). Less than one-quarter of RCTs with results published in a sample of oral health journals were registered with a public registry. Improvements are needed with respect to how journals inform and require their authors to register their trials. © International & American Associations for Dental Research.

  7. The Importance of Soil Protein Fate to PIP Crop Registration

    EPA Science Inventory

    Plant Incorporated Protectant (PIP) crops are registered under the authority of the Federal Insecticide Fungicide and Rodenticide Act (FIFRA) and as part of this registration certain environmental fate information is required to properly judge the environmental compatibility of n...

  8. A novel surface registration algorithm with biomedical modeling applications.

    PubMed

    Huang, Heng; Shen, Li; Zhang, Rong; Makedon, Fillia; Saykin, Andrew; Pearlman, Justin

    2007-07-01

    In this paper, we propose a novel surface matching algorithm for arbitrarily shaped but simply connected 3-D objects. The spherical harmonic (SPHARM) method is used to describe these 3-D objects, and a novel surface registration approach is presented. The proposed technique is applied to various applications of medical image analysis. The results are compared with those using the traditional method, in which the first-order ellipsoid is used for establishing surface correspondence and aligning objects. In these applications, our surface alignment method is demonstrated to be more accurate and flexible than the traditional approach. This is due in large part to the fact that a new surface parameterization is generated by a shortcut that employs a useful rotational property of spherical harmonic basis functions for a fast implementation. In order to achieve a suitable computational speed for practical applications, we propose a fast alignment algorithm that improves computational complexity of the new surface registration method from O(n3) to O(n2).

  9. Plasma n-3 and n-6 fatty acids and inflammatory markers in Chinese vegetarians.

    PubMed

    Yu, Xiaomei; Huang, Tao; Weng, Xiumei; Shou, Tianxing; Wang, Qiang; Zhou, Xiaoqiong; Hu, Qinxin; Li, Duo

    2014-09-29

    Polyunsaturated fatty acid (PUFA) intake favorably affects chronic inflammatory-related diseases such as cardiovascular disease; however, the relationship between the PUFA and inflammatory factors in the healthy vegetarians were not clear. We aimed to investigate the plasma fatty acids status, and its association with plasma inflammatory factors in Chinese vegetarians and omnivores. A total of 89 male vegetarians and 106 male omnivores were participated the study. Plasma concentrations of inflammatory factors were detected by ELISA, and as standard methods fatty acids were extracted and determined by chromatography. Compared with omnivores, vegetarians have significant higher interleukin-6 (IL-6), plasma n-6 PUFA, n-6/n-3, and 18:3n-3; while they have significant lower leukotriene B4 (LTB4), cyclo-oxygenase-2 (COX2) and prostaglandin E2 (PGE2), 20:5n-3, 22:5n-3, 22:6n-3, and n-3 PUFA. In vegetarians, plasma 20:4n-6 was significant positively related to TNF-α. LTB4 was significantly positively related to plasma 22:6n-3, and negatively associated with n-6 PUFA. Vegetarians have higher plasma n-6 PUFA and IL-6, but lower LTB4, n-3 PUFA, 22:6n-3, COX2 and PGE2 levels. It would seem appropriate for vegetarians to increase their dietary n-3 PUFA, while reduce dietary n-6 PUFA and thus reduce the risk of chronic inflammatory-related diseases.

  10. 17 CFR 240.3b-6 - Liability for certain statements by issuers.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... proved oil and gas reserves as set forth in paragraphs 30-34 of Statement of Financial Accounting... Regulation S-K (§ 229.303 of this chapter), “Management's Discussion and Analysis of Financial Condition and Results of Operations,” Item 5 of Form 20-F (§ 240.220(f) of this chapter), “Operating and Financial...

  11. Registration for deceased organ and tissue donation among Ontario immigrants: a population-based cross-sectional study

    PubMed Central

    Li, Alvin Ho-ting; Lam, Ngan N.; Dhanani, Sonny; Weir, Matthew; Prakash, Versha; Kim, Joseph; Knoll, Greg; Garg, Amit X.

    2016-01-01

    Background: Canada has low rates of deceased organ and tissue donation. Immigrants to Canada may differ in their registered support for deceased organ donation based on their country of origin. Methods: We used linked administrative databases in Ontario (about 11 million residents aged ≥ 16 yr) to study the proportion of immigrants and long-term residents registered for deceased organ and tissue donation as of October 2013. We used modified Poisson regression to identify and quantify predictors of donor registration. Results: Compared with long-term residents (n = 9 244 570), immigrants (n = 1 947 646) were much less likely to register for deceased organ and tissue donation (11.9% v. 26.5%). Immigrants from the United States, Australia and New Zealand had the highest registration rate (40.0%), whereas immigrants with the lowest registration rates were from Eastern Europe and Central Asia (9.4%), East Asia and Pacific (8.4%) and sub-Saharan Africa (7.9%). The largest numbers of unregistered immigrants were from India (n = 202 548), China (n = 186 678) and the Philippines (n = 125 686). Characteristics among the immigrant population associated with a higher likelihood of registration included economic immigrant status, living in a rural area (population < 10 000), living in an area with a lower ethnic concentration, less material deprivation, a higher education, ability to speak English and French, and more years residing in Canada. Interpretation: Immigrants in Ontario were less likely to register for deceased organ and tissue donation than long-term residents. There is a need to better understand reasons for lower registration rates among Canadian immigrants and to create culture-sensitive materials to build support for deceased organ and tissue donation. PMID:28443265

  12. 14 CFR 47.61 - Dealer's Aircraft Registration Certificates.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Dealer's Aircraft Registration Certificates... TRANSPORTATION AIRCRAFT AIRCRAFT REGISTRATION Dealers' Aircraft Registration Certificate § 47.61 Dealer's Aircraft Registration Certificates. (a) The FAA issues a Dealer's Aircraft Registration Certificate, AC...

  13. 14 CFR 47.61 - Dealer's Aircraft Registration Certificates.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Dealer's Aircraft Registration Certificates... TRANSPORTATION AIRCRAFT AIRCRAFT REGISTRATION Dealers' Aircraft Registration Certificate § 47.61 Dealer's Aircraft Registration Certificates. (a) The FAA issues a Dealer's Aircraft Registration Certificate, AC...

  14. 14 CFR 47.61 - Dealer's Aircraft Registration Certificates.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Dealer's Aircraft Registration Certificates... TRANSPORTATION AIRCRAFT AIRCRAFT REGISTRATION Dealers' Aircraft Registration Certificate § 47.61 Dealer's Aircraft Registration Certificates. (a) The FAA issues a Dealer's Aircraft Registration Certificate, AC...

  15. 14 CFR 47.61 - Dealer's Aircraft Registration Certificates.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Dealer's Aircraft Registration Certificates... TRANSPORTATION AIRCRAFT AIRCRAFT REGISTRATION Dealers' Aircraft Registration Certificate § 47.61 Dealer's Aircraft Registration Certificates. (a) The FAA issues a Dealer's Aircraft Registration Certificate, AC...

  16. 14 CFR 47.61 - Dealers' Aircraft Registration Certificates.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Dealers' Aircraft Registration Certificates... TRANSPORTATION AIRCRAFT AIRCRAFT REGISTRATION Dealers' Aircraft Registration Certificate § 47.61 Dealers' Aircraft Registration Certificates. (a) The FAA issues a Dealers' Aircraft Registration Certificate, AC...

  17. 40 CFR 164.21 - Contents of a denial of registration, notice of intent to cancel a registration, or notice of...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., notice of intent to cancel a registration, or notice of intent to change a classification. 164.21 Section... denial of registration, notice of intent to cancel a registration, or notice of intent to change a classification. (a) Contents. The denial of registration or a notice of intent to cancel a registration or to...

  18. Corporate environmental policy statements in mainland China: to what extent do they conform to ISO 14000 documentation?

    PubMed

    Chung, Shan Shan; Fryxell, Gerald E; Lo, Carlos W H

    2005-04-01

    For decades, industry has been the main source of pollution in China. Determined to make changes, the mainland Chinese authorities have decided to promote mechanisms that incorporate environmental concerns into the internal management of enterprises. This is manifested in the rapid adoption of the ISO14000 standards, including a significant increase in ISO14001 registrations in China. Thus, this study examined the environmental policy statements of 106 certified facilities in mainland China against a strict interpretation of the mandatory requirements of the ISO 14001:1996 standard and the nonmandatory ISO14004 requirements in order to shed some light on the implementation of environmental management systems in an emerging economic giant. It was decided to analyze the environmental policy statement because such a statement is a core element in the ISO system of environmental management of each facility and there are relatively clear and specific requirements on what an environmental policy statement shall include. An analysis of the contents of the environmental policy statements shows that conformance to the relevant requirements of both the mandatory ISO14001 standard and the nonmandatory ISO14004 standard is far from impressive and that the facilities in our sample seldom went beyond the minimum requirements. By using ISO14001 and ISO14004 conformance scores as the dependent variables, we found that conformity to ISO14001 and overall conformance to ISO14000 series can be explained to some extent by the degree of top management commitment, the experience with informal environmental management systems, and the form of ownership of the facilities.

  19. 49 CFR 520.24 - Internal processing of draft environmental impact statements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 6 2014-10-01 2014-10-01 false Internal processing of draft environmental impact statements. 520.24 Section 520.24 Transportation Other Regulations Relating to Transportation (Continued... ENVIRONMENTAL IMPACTS Procedures § 520.24 Internal processing of draft environmental impact statements. Before...

  20. 49 CFR 520.24 - Internal processing of draft environmental impact statements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 6 2011-10-01 2011-10-01 false Internal processing of draft environmental impact statements. 520.24 Section 520.24 Transportation Other Regulations Relating to Transportation (Continued... ENVIRONMENTAL IMPACTS Procedures § 520.24 Internal processing of draft environmental impact statements. Before...

  1. 49 CFR 520.24 - Internal processing of draft environmental impact statements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 6 2012-10-01 2012-10-01 false Internal processing of draft environmental impact statements. 520.24 Section 520.24 Transportation Other Regulations Relating to Transportation (Continued... ENVIRONMENTAL IMPACTS Procedures § 520.24 Internal processing of draft environmental impact statements. Before...

  2. 49 CFR 520.24 - Internal processing of draft environmental impact statements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 6 2013-10-01 2013-10-01 false Internal processing of draft environmental impact statements. 520.24 Section 520.24 Transportation Other Regulations Relating to Transportation (Continued... ENVIRONMENTAL IMPACTS Procedures § 520.24 Internal processing of draft environmental impact statements. Before...

  3. The Consolidated Standards of Reporting Trials (CONSORT) Statement applied to allergen-specific immunotherapy with inhalant allergens: a Global Allergy and Asthma European Network (GA(2)LEN) article.

    PubMed

    Bousquet, Philippe J; Calderón, Moisés A; Demoly, Pascal; Larenas, Désirée; Passalacqua, Giovanni; Bachert, Claus; Brozek, Jan; Canonica, G Walter; Casale, Thomas; Fonseca, Joao; Dahl, Ronald; Durham, Stephen R; Merk, Hans; Worm, Margitta; Wahn, Ulrich; Zuberbier, Torsten; Schünemann, Holger J; Bousquet, Jean

    2011-01-01

    Randomized trials provide evidence to inform treatment decisions. The Consolidated Standards of Reporting Trials (CONSORT) Statement is a set of recommendations for the reporting of trials. We sought to assess the quality of reporting allergen-specific immunotherapy trials according to CONSORT criteria. The reporting of the procedure, randomization, dropouts, strict conduct of intention-to-treat (ITT) analysis, and sample size calculation according to CONSORT were assessed in the 46 subcutaneous and 48 sublingual immunotherapy (SLIT) blind, placebo-controlled randomized trials published between 1996 and 2009 in English. One subcutaneous immunotherapy (2.2%) and 3 SLIT (6.6%) trials met CONSORT Statement criteria. These were used for the registration of sublingual tablets to the European Medicines Agency. In subcutaneous immunotherapy, 16 (35%) studies reported a CONSORT flow chart, and 12 (26%) provided a description of dropouts. Adequate randomization was reported in 9 (35%) studies, and incomplete randomization was reported in 15 (33%). Power analysis was reported in 15 (33%) studies. In SLIT, 20 (42%) studies reported a CONSORT flow chart, and 16 (32%) a description of dropouts. ITT analysis was carried out in 1 (2.2%) SLIT study, and a modified ITT analysis was used in 1 (2.2%) subcutaneous immunotherapy study and 2 (4.4%) SLIT studies. Adequate randomization was reported in 6 (12%) studies, and incomplete randomization was reported in 16 (32%). Power analysis was reported in 15 (27%) studies. As in other areas of medicine, the quality of reporting of most immunotherapy trials is low, and only 4.2% of SLIT randomized controlled trials met all of the criteria of the CONSORT Statement. Use of the CONSORT criteria should be encouraged. Copyright © 2010 American Academy of Allergy, Asthma & Immunology. Published by Mosby, Inc. All rights reserved.

  4. 40 CFR 155.56 - Interim registration review decision.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Interim registration review decision... PROGRAMS REGISTRATION STANDARDS AND REGISTRATION REVIEW Registration Review Procedures § 155.56 Interim registration review decision. The Agency may issue, when it determines it to be appropriate, an interim...

  5. 14 CFR 47.40 - Registration expiration and renewal.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... AIRCRAFT REGISTRATION Certificates of Aircraft Registration § 47.40 Registration expiration and renewal. (a) Re-registration. Each aircraft registered under this part before October 1, 2010, must be re-registered in accordance with this paragraph (a). (1) A Certificate of Aircraft Registration issued before...

  6. 14 CFR 47.40 - Registration expiration and renewal.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... AIRCRAFT REGISTRATION Certificates of Aircraft Registration § 47.40 Registration expiration and renewal. (a) Re-registration. Each aircraft registered under this part before October 1, 2010, must be re-registered in accordance with this paragraph (a). (1) A Certificate of Aircraft Registration issued before...

  7. 14 CFR 47.40 - Registration expiration and renewal.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... AIRCRAFT REGISTRATION Certificates of Aircraft Registration § 47.40 Registration expiration and renewal. (a) Re-registration. Each aircraft registered under this part before October 1, 2010, must be re-registered in accordance with this paragraph (a). (1) A Certificate of Aircraft Registration issued before...

  8. 75 FR 54196 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-03

    ... Combination Transactions by Investment Companies and Business Development Companies. Form N-14 is used by... Act'') to be issued in business combination transactions specified in rule 145(a) under the Securities... business combination transactions. The Commission staff reviews registration statements on Form N-14 for...

  9. Explicit B-spline regularization in diffeomorphic image registration

    PubMed Central

    Tustison, Nicholas J.; Avants, Brian B.

    2013-01-01

    Diffeomorphic mappings are central to image registration due largely to their topological properties and success in providing biologically plausible solutions to deformation and morphological estimation problems. Popular diffeomorphic image registration algorithms include those characterized by time-varying and constant velocity fields, and symmetrical considerations. Prior information in the form of regularization is used to enforce transform plausibility taking the form of physics-based constraints or through some approximation thereof, e.g., Gaussian smoothing of the vector fields [a la Thirion's Demons (Thirion, 1998)]. In the context of the original Demons' framework, the so-called directly manipulated free-form deformation (DMFFD) (Tustison et al., 2009) can be viewed as a smoothing alternative in which explicit regularization is achieved through fast B-spline approximation. This characterization can be used to provide B-spline “flavored” diffeomorphic image registration solutions with several advantages. Implementation is open source and available through the Insight Toolkit and our Advanced Normalization Tools (ANTs) repository. A thorough comparative evaluation with the well-known SyN algorithm (Avants et al., 2008), implemented within the same framework, and its B-spline analog is performed using open labeled brain data and open source evaluation tools. PMID:24409140

  10. 18 CFR 390.1 - Electronic registration.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Electronic registration. 390.1 Section 390.1 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY PROCEDURAL RULES ELECTRONIC REGISTRATION § 390.1 Electronic registration. Any person who...

  11. 18 CFR 390.1 - Electronic registration.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Electronic registration. 390.1 Section 390.1 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY PROCEDURAL RULES ELECTRONIC REGISTRATION § 390.1 Electronic registration. Any person who...

  12. 18 CFR 390.1 - Electronic registration.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Electronic registration. 390.1 Section 390.1 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY PROCEDURAL RULES ELECTRONIC REGISTRATION § 390.1 Electronic registration. Any person who...

  13. 18 CFR 390.1 - Electronic registration.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Electronic registration. 390.1 Section 390.1 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY PROCEDURAL RULES ELECTRONIC REGISTRATION § 390.1 Electronic registration. Any person who...

  14. 18 CFR 390.1 - Electronic registration.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Electronic registration. 390.1 Section 390.1 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY PROCEDURAL RULES ELECTRONIC REGISTRATION § 390.1 Electronic registration. Any person who...

  15. A survey of medical image registration - under review.

    PubMed

    Viergever, Max A; Maintz, J B Antoine; Klein, Stefan; Murphy, Keelin; Staring, Marius; Pluim, Josien P W

    2016-10-01

    A retrospective view on the past two decades of the field of medical image registration is presented, guided by the article "A survey of medical image registration" (Maintz and Viergever, 1998). It shows that the classification of the field introduced in that article is still usable, although some modifications to do justice to advances in the field would be due. The main changes over the last twenty years are the shift from extrinsic to intrinsic registration, the primacy of intensity-based registration, the breakthrough of nonlinear registration, the progress of inter-subject registration, and the availability of generic image registration software packages. Two problems that were called urgent already 20 years ago, are even more urgent nowadays: Validation of registration methods, and translation of results of image registration research to clinical practice. It may be concluded that the field of medical image registration has evolved, but still is in need of further development in various aspects. Copyright © 2016 Elsevier B.V. All rights reserved.

  16. Image registration reveals central lens thickness minimally increases during accommodation

    PubMed Central

    Schachar, Ronald A; Mani, Majid; Schachar, Ira H

    2017-01-01

    Purpose To evaluate anterior chamber depth, central crystalline lens thickness and lens curvature during accommodation. Setting California Retina Associates, El Centro, CA, USA. Design Healthy volunteer, prospective, clinical research swept-source optical coherence biometric image registration study of accommodation. Methods Ten subjects (4 females and 6 males) with an average age of 22.5 years (range: 20–26 years) participated in the study. A 45° beam splitter attached to a Zeiss IOLMaster 700 (Carl Zeiss Meditec Inc., Jena, Germany) biometer enabled simultaneous imaging of the cornea, anterior chamber, entire central crystalline lens and fovea in the dilated right eyes of subjects before, and during focus on a target 11 cm from the cornea. Images with superimposable foveal images, obtained before and during accommodation, that met all of the predetermined alignment criteria were selected for comparison. This registration requirement assured that changes in anterior chamber depth and central lens thickness could be accurately and reliably measured. The lens radii of curvatures were measured with a pixel stick circle. Results Images from only 3 of 10 subjects met the predetermined criteria for registration. Mean anterior chamber depth decreased, −67 μm (range: −0.40 to −110 μm), and mean central lens thickness increased, 117 μm (range: 100–130 μm). The lens surfaces steepened, anterior greater than posterior, while the lens, itself, did not move or shift its position as appeared from the lack of movement of the lens nucleus, during 7.8 diopters of accommodation, (range: 6.6–9.7 diopters). Conclusion Image registration, with stable invariant references for image correspondence, reveals that during accommodation a large increase in lens surface curvatures is associated with only a small increase in central lens thickness and no change in lens position. PMID:28979092

  17. Deformable planning CT to cone-beam CT image registration in head-and-neck cancer

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hou Jidong; Guerrero, Mariana; Chen, Wenjuan

    2011-04-15

    Purpose: The purpose of this work was to implement and validate a deformable CT to cone-beam computed tomography (CBCT) image registration method in head-and-neck cancer to eventually facilitate automatic target delineation on CBCT. Methods: Twelve head-and-neck cancer patients underwent a planning CT and weekly CBCT during the 5-7 week treatment period. The 12 planning CT images (moving images) of these patients were registered to their weekly CBCT images (fixed images) via the symmetric force Demons algorithm and using a multiresolution scheme. Histogram matching was used to compensate for the intensity difference between the two types of images. Using nine knownmore » anatomic points as registration targets, the accuracy of the registration was evaluated using the target registration error (TRE). In addition, region-of-interest (ROI) contours drawn on the planning CT were morphed to the CBCT images and the volume overlap index (VOI) between registered contours and manually delineated contours was evaluated. Results: The mean TRE value of the nine target points was less than 3.0 mm, the slice thickness of the planning CT. Of the 369 target points evaluated for registration accuracy, the average TRE value was 2.6{+-}0.6 mm. The mean TRE for bony tissue targets was 2.4{+-}0.2 mm, while the mean TRE for soft tissue targets was 2.8{+-}0.2 mm. The average VOI between the registered and manually delineated ROI contours was 76.2{+-}4.6%, which is consistent with that reported in previous studies. Conclusions: The authors have implemented and validated a deformable image registration method to register planning CT images to weekly CBCT images in head-and-neck cancer cases. The accuracy of the TRE values suggests that they can be used as a promising tool for automatic target delineation on CBCT.« less

  18. 75 FR 38853 - Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-06

    ... SECURITIES AND EXCHANGE COMMISSION [Form N-14; SEC File No. 270-297; OMB Control No. 3235-0336... Commission, Office of Investor Education and Advocacy, Washington, DC 20549-0213. Extension: Form N-14, SEC... approval. Form N-14 (17 CFR 239.23)--Registration Statement Under the Securities Act of 1933 for Securities...

  19. MO-C-17A-13: Uncertainty Evaluation of CT Image Deformable Registration for H and N Cancer Adaptive Radiotherapy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Qin, A; Yan, D

    2014-06-15

    Purpose: To evaluate uncertainties of organ specific Deformable Image Registration (DIR) for H and N cancer Adaptive Radiation Therapy (ART). Methods: A commercial DIR evaluation tool, which includes a digital phantom library of 8 patients, and the corresponding “Ground truth Deformable Vector Field” (GT-DVF), was used in the study. Each patient in the phantom library includes the GT-DVF created from a pair of CT images acquired prior to and at the end of the treatment course. Five DIR tools, including 2 commercial tools (CMT1, CMT2), 2 in-house (IH-FFD1, IH-FFD2), and a classic DEMON algorithms, were applied on the patient images.more » The resulting DVF was compared to the GT-DVF voxel by voxel. Organ specific DVF uncertainty was calculated for 10 ROIs: Whole Body, Brain, Brain Stem, Cord, Lips, Mandible, Parotid, Esophagus and Submandibular Gland. Registration error-volume histogram was constructed for comparison. Results: The uncertainty is relatively small for brain stem, cord and lips, while large in parotid and submandibular gland. CMT1 achieved best overall accuracy (on whole body, mean vector error of 8 patients: 0.98±0.29 mm). For brain, mandible, parotid right, parotid left and submandibular glad, the classic Demon algorithm got the lowest uncertainty (0.49±0.09, 0.51±0.16, 0.46±0.11, 0.50±0.11 and 0.69±0.47 mm respectively). For brain stem, cord and lips, the DVF from CMT1 has the best accuracy (0.28±0.07, 0.22±0.08 and 0.27±0.12 mm respectively). All algorithms have largest right parotid uncertainty on patient #7, which has image artifact caused by tooth implantation. Conclusion: Uncertainty of deformable CT image registration highly depends on the registration algorithm, and organ specific. Large uncertainty most likely appears at the location of soft-tissue organs far from the bony structures. Among all 5 DIR methods, the classic DEMON and CMT1 seem to be the best to limit the uncertainty within 2mm for all OARs. Partially supported by

  20. Analysis of deformable image registration accuracy using computational modeling

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhong Hualiang; Kim, Jinkoo; Chetty, Indrin J.

    2010-03-15

    Computer aided modeling of anatomic deformation, allowing various techniques and protocols in radiation therapy to be systematically verified and studied, has become increasingly attractive. In this study the potential issues in deformable image registration (DIR) were analyzed based on two numerical phantoms: One, a synthesized, low intensity gradient prostate image, and the other a lung patient's CT image data set. Each phantom was modeled with region-specific material parameters with its deformation solved using a finite element method. The resultant displacements were used to construct a benchmark to quantify the displacement errors of the Demons and B-Spline-based registrations. The results showmore » that the accuracy of these registration algorithms depends on the chosen parameters, the selection of which is closely associated with the intensity gradients of the underlying images. For the Demons algorithm, both single resolution (SR) and multiresolution (MR) registrations required approximately 300 iterations to reach an accuracy of 1.4 mm mean error in the lung patient's CT image (and 0.7 mm mean error averaged in the lung only). For the low gradient prostate phantom, these algorithms (both SR and MR) required at least 1600 iterations to reduce their mean errors to 2 mm. For the B-Spline algorithms, best performance (mean errors of 1.9 mm for SR and 1.6 mm for MR, respectively) on the low gradient prostate was achieved using five grid nodes in each direction. Adding more grid nodes resulted in larger errors. For the lung patient's CT data set, the B-Spline registrations required ten grid nodes in each direction for highest accuracy (1.4 mm for SR and 1.5 mm for MR). The numbers of iterations or grid nodes required for optimal registrations depended on the intensity gradients of the underlying images. In summary, the performance of the Demons and B-Spline registrations have been quantitatively evaluated using numerical phantoms. The results show that

Some links on this page may take you to non-federal websites. Their policies may differ from this site.