Sample records for nacional dr juan

  1. Mediastinal pathology and the contributions of Dr. Juan Rosai.

    PubMed

    Wick, Mark R

    2016-09-01

    Dr. Juan Rosai is one of the most prolific contributors to the literature on mediastinal pathology, and he has added steadily to that body of work over a 50-year period. Rosai has written several landmark articles in this topical area, including articles on thymic epithelial lesions, mediastinal neuroendocrine tumors, mediastinal lymphoma and other hematopoietic lesions, thymolipoma, thymoliposarcoma, mediastinal solitary fibrous tumor, intrathymic langerhans-cell histiocytosis, mediastinal germ cell neoplasms, and multilocular thymic cyst. This review recounts his role as one of the principal figures in the surgical pathology of mediastinal diseases. Copyright © 2016 Elsevier Inc. All rights reserved.

  2. 8th Argentinean Bioengineering Society Conference (SABI 2011) and 7th Clinical Engineering Meeting

    NASA Astrophysics Data System (ADS)

    Meschino, Gustavo Javier; Ballarin, Virginia L.

    2011-12-01

    In September 2011, the Eighteenth Edition of the Argentinean Bioengineering Society Conference (SABI 2011) and Seventh Clinical Engineering Meeting were held in Mar del Plata, Argetina. The Mar del Plata SABI Regional and the School of Engineering of the Universidad Nacional de Mar del Plata invited All bioengineers, engineers, physicists, mathematicians, biologists, physicians and health professionals working in the field of Bioengineering to participate in this event. The overall objectives of the Conference were: To provide discussion of scientific research results in Bioengineering and Clinical Engineering. To promote technological development experiences. To strengthen the institutional and scientific communication links in the area of Bioengineering, mainly between Universities of Latin America. To encourage students, teachers, researchers and professionals to establish exchanges of experiences and knowledge. To provide biomedical engineering technology solutions to the society and contributing ideas for low cost care. Conference photograph Conference photograph Conference photograph Conference photograph EXECUTIVE COMMITTEE SABI 2011 Chair Dra Virginia L Ballarin Universidad Nacional de Mar del Plata Co-Chair Dra Teresita R Cuadrado Universidad Nacional de Mar del Plata - CONICET Local Comittee Dr Gustavo Abraham Universidad Nacional de Mar del Plata - CONICET Dra Josefina Ballarre Universidad Nacional de Mar del Plata - CONICET Dr Eduardo Blotta Universidad Nacional de Mar del Plata Dra Agustina Bouchet Universidad Nacional de Mar del Plata Dr Marcel Brun Universidad Nacional de Mar del Plata Dra Silvia Ceré Universidad Nacional de Mar del Plata - CONICET Dra Mariela Azul Gonzalez Universidad Nacional de Mar del Plata - CONICET Dra Lucia Isabel Passoni Universidad Nacional de Mar del Plata Dr Juan Ignacio Pastore Universidad Nacional de Mar del Plata - CONICET Dra Adriana Scandurra Universidad Nacional de Mar del Plata SCIENTIFIC ADVISORY COMMITTEE

  3. [Children's Psychiatric Hospital Dr. Juan N. Navarro: 50 years of attention to the mental health of children and adolescents in Mexico].

    PubMed

    Márquez-Caraveo, Maria Elena; Arroyo-García, Eduardo; Granados-Rojas, Armida; Ángeles-Llerenas, Angélica

    2017-01-01

    The activities concerning mental health care of psychiatric disorders during more than 50 years of service (1966-2016) at the Children's Psychiatric Hospital "Dr. Juan N. Navarro" (HPI), as well as the progressive development of teaching and research, have contributed to its positioning as a leading institution in medical care of high specialization. This has been possible through the training of human resources that focus the quality of care to the children and their families. The hospital has progressed towards diagnostic and therapeutic care of outpatients through the creation of specialized clinics (emotions, behavior, development, adolescence, among others) and the development of more actualized and integral therapeutic programs (behavioral psychotherapy, cognitive behavioral, psychodynamic; individual, group, family, etc.). In the field of education, the hospital has been the most important institution in the training of child psychiatrists in Mexico and its recognition as a research interdisciplinary center has grown.

  4. 33 CFR 165.776 - Security Zone; Coast Guard Base San Juan, San Juan Harbor, Puerto Rico

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Security Zone; Coast Guard Base San Juan, San Juan Harbor, Puerto Rico 165.776 Section 165.776 Navigation and Navigable Waters COAST... Guard District § 165.776 Security Zone; Coast Guard Base San Juan, San Juan Harbor, Puerto Rico (a...

  5. 33 CFR 165.776 - Security Zone; Coast Guard Base San Juan, San Juan Harbor, Puerto Rico

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Security Zone; Coast Guard Base San Juan, San Juan Harbor, Puerto Rico 165.776 Section 165.776 Navigation and Navigable Waters COAST... Guard District § 165.776 Security Zone; Coast Guard Base San Juan, San Juan Harbor, Puerto Rico (a...

  6. 33 CFR 165.776 - Security Zone; Coast Guard Base San Juan, San Juan Harbor, Puerto Rico.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Security Zone; Coast Guard Base San Juan, San Juan Harbor, Puerto Rico. 165.776 Section 165.776 Navigation and Navigable Waters COAST... Guard District § 165.776 Security Zone; Coast Guard Base San Juan, San Juan Harbor, Puerto Rico. (a...

  7. 33 CFR 165.776 - Security Zone; Coast Guard Base San Juan, San Juan Harbor, Puerto Rico.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Security Zone; Coast Guard Base San Juan, San Juan Harbor, Puerto Rico. 165.776 Section 165.776 Navigation and Navigable Waters COAST... Guard District § 165.776 Security Zone; Coast Guard Base San Juan, San Juan Harbor, Puerto Rico. (a...

  8. 75 FR 51098 - Protection Island and San Juan Islands National Wildlife Refuges, Jefferson, Island, San Juan...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-18

    ..., Washington Maritime National Wildlife Refuge Complex, 715 Holgerson Drive, Sequim, WA 98382. FOR FURTHER...] Protection Island and San Juan Islands National Wildlife Refuges, Jefferson, Island, San Juan, Skagit, and Whatcom Counties, WA AGENCY: Fish and Wildlife Service, Interior. ACTION: Notice of availability: draft...

  9. 76 FR 19781 - Protection Island and San Juan Islands National Wildlife Refuges, Jefferson, San Juan, Skagit...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-08

    ...., Lopez Island, WA 98261. North Olympic Public Library..... 630 N. Sequim Ave., 360-683-1161 Sequim, WA...] Protection Island and San Juan Islands National Wildlife Refuges, Jefferson, San Juan, Skagit, Island, and Whatcom Counties, WA; Final Comprehensive Conservation Plan, Wilderness Stewardship Plan, and Finding of...

  10. El círculo meridiano automático de San Fernando - San Juan. Sus primeros pasos en el hemisferio sur

    NASA Astrophysics Data System (ADS)

    Mallamaci, C. C.; Muiños, J. L.; Gallego, M.; Pérez, J. A.; Marmolejo, L.; Navarro, J. L.; Sedeño, J.; Vallejos, M.; Belizón, F.

    Se informa sobre el estado actual del Círculo Meridiano Automático de San Fernando-San Juan. El instrumento (Grubb-Parson, de 178mm de abertura y 2665 mm de distancia focal) es gemelo del que se encuentra en las Islas Canarias, y fue instalado durante los meses de julio y agosto de 1996 en la estación astronómica ``Dr. C.U.Cesco" (El Leoncito, Barreal), a unos 200 km de distancia de la ciudad de San Juan, merced a un Convenio de Cooperación Científica, firmado en 1994 entre el ROA (España) y el OAFA (Argentina). En la actualidad se está llevando a cabo un programa de prueba cuyos resultados preliminares muestran que el telescopio está en buenas condiciones para observar estrellas de hasta magnitud aproximada 14.5, con buenos errores de observación (<0.12" en ascensión recta y declinación).

  11. On New Spain and Mexican medicinal botany in cardiology.

    PubMed

    de Micheli-Serra, Alfredo Alessandro; Izaguirre-Ávila, Raúl

    2014-01-01

    Towards the middle of the XVI century, the empirical physician Martín de la Cruz, in New Spain, compiled a catalogue of the local medicinal herbs and plants, which was translated into Latin by Juan Badiano, professor at the Franciscan college of Tlatelolco. On his side, Dr. Francisco Hernández, the royal physician (protomédico) from 1571 until 1577, performed a systematic study of the flora and fauna in this period. His notes and designs were not published at that time, but two epitomes of Hernández' works appeared, respectively, in 1615 in Mexico and in 1651 in Rome. During the XVIII century, two Spanish scientific expeditions arrived to these lands. They were led, respectively, by the Spanish naturalist Martín Sessé and the Italian seaman, Alessandro Malaspina di Mulazzo, dependent from the Spanish Government. These expeditions collected and carried rich scientific material to Spain. At the end of that century, the Franciscan friar Juan Navarro depicted and described several Mexican medicinal plants in the fifth volume of his botanic work. In the last years of the colonial period, the fundamental works of Humboldt and Bonpland on the geographic distribution of the American plants were published. In the modern age, the first research about the Mexican medicinal botany was performed in the laboratory of the Instituto Médico Nacional [National Medical Institute] under the leadership of Dr. Fernando Altamirano, who started pharmacological studies in this country. Later, trials of cardiovascular pharmacology were performed in the small laboratories of the cardiological unit at the General Hospital of Mexico City, on Dr. Ignacio Chávez' initiative. The Mexican botanical-pharmacological tradition persists alive and vigorous at the Instituto Nacional de Cardiología and other scientific institutions of the country.

  12. 33 CFR 80.1385 - Strait of Juan de Fuca.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Strait of Juan de Fuca. 80.1385... NAVIGATION RULES COLREGS DEMARCATION LINES Thirteenth District § 80.1385 Strait of Juan de Fuca. The 72 COLREGS shall apply on all waters of the Strait of Juan de Fuca. [CGD 81-087, 46 FR 61457, Dec. 17, 1981...

  13. 33 CFR 80.1385 - Strait of Juan de Fuca.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Strait of Juan de Fuca. 80.1385... NAVIGATION RULES COLREGS DEMARCATION LINES Thirteenth District § 80.1385 Strait of Juan de Fuca. The 72 COLREGS shall apply on all waters of the Strait of Juan de Fuca. [CGD 81-087, 46 FR 61457, Dec. 17, 1981...

  14. 33 CFR 110.74c - Bahia de San Juan, PR.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Bahia de San Juan, PR. 110.74c... ANCHORAGE REGULATIONS Special Anchorage Areas § 110.74c Bahia de San Juan, PR. The waters of San Antonio Channel, Bahia de San Juan, eastward of longitude 66°05′45″ W. [CGD 7-83-29, 49 FR 48540, Dec. 13, 1984] ...

  15. 33 CFR 110.74c - Bahia de San Juan, PR.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Bahia de San Juan, PR. 110.74c... ANCHORAGE REGULATIONS Special Anchorage Areas § 110.74c Bahia de San Juan, PR. The waters of San Antonio Channel, Bahia de San Juan, eastward of longitude 66°05′45″ W. [CGD 7-83-29, 49 FR 48540, Dec. 13, 1984] ...

  16. [Juan Marin Rojas M.D., First Professor of History of Medicine at Universidad de Chile and his "Essay about the origin of syphilis"].

    PubMed

    Laval, Enrique

    2014-06-01

    Dr. Juan Marín Rojas, M.D., was the first Professor of History of Medicine at Universidad de Chile, navy doctor, diplomat, writer and literary critic. Member of the International Society of History of Medicine, and Correspondent Member for Chile of the "Office de Documentation de Médecine et Pharmacie Militaire", Liege, Belgium, from which his "Essay about the origin of syphilis" is transcribed with interesting historical facts and little known arguments that affirm the non-american origin of syphilis, but "aspire to leave a doubt, given not a contrary conviction".

  17. Juan Gabriel and audience interpretation. cultural impressions of effeminacy and sexuality in Mexico.

    PubMed

    Sowards, S K

    2000-01-01

    Juan Gabriel's purported effeminacy and sexuality have made him a controversial subject in Mexico, but still loved by fans. Juan Gabriel, by trying to gain acceptance into Mexican society, has become part of a hybrid culture, between the feminine/masculine and homosexual/bisexual/heterosexual groups. This study focuses on interviews with 20 participants who discuss Juan Gabriel's popularity and sexuality. The findings of the study indicate that Juan Gabriel may be considered by his fans to be effeminate, and consequently homosexual. Even though homophobia is widespread in Mexico, Juan Gabriel's fans tend to ignore or exoticize his sexuality, thus affording his success. It is also possible that Juan Gabriel, consciously or not, uses his controversial sexuality as a way to generate popular interest.

  18. Hydrologic assessment and numerical simulation of groundwater flow, San Juan Mine, San Juan County, New Mexico, 2010–13

    USGS Publications Warehouse

    Stewart, Anne M.

    2018-04-03

    Coal combustion byproducts (CCBs), which are composed of fly ash, bottom ash, and flue gas desulfurization material, produced at the coal-fired San Juan Generating Station (SJGS), located in San Juan County, New Mexico, have been buried in former surface-mine pits at the San Juan Mine, also referred to as the San Juan Coal Mine, since operations began in the early 1970s. This report, prepared by the U.S. Geological Survey in cooperation with the Mining and Minerals Division of the New Mexico Energy, Minerals and Natural Resources Department, describes results of a hydrogeologic assessment, including numerical groundwater modeling, to identify the timing of groundwater recovery and potential pathways for groundwater transport of metals that may be leached from stored CCBs and reach hydrologic receptors after operations cease. Data collected for the hydrologic assessment indicate that groundwater in at least one centrally located reclaimed surface-mining pit has already begun to recover.The U.S. Geological Survey numerical modeling package MODFLOW–NWT was used with MODPATH particle-tracking software to identify advective flow paths from CCB storage areas toward potential hydrologic receptors. Results indicate that groundwater at CCB storage areas will recover to the former steady state, or in some locations, groundwater may recover to a new steady state in 6,600 to 10,600 years at variable rates depending on the proximity to a residual cone-of-groundwater depression caused by mine dewatering and regional oil and gas pumping as well as on actual, rather than estimated, groundwater recharge and evapotranspirational losses. Advective particle-track modeling indicates that the number of particles and rates of advective transport will vary depending on hydraulic properties of the mine spoil, particularly hydraulic conductivity and porosity. Modeling results from the most conservative scenario indicate that particles can migrate from CCB repositories to either the

  19. San Juan Ultra (Mooklabs)

    Science.gov Websites

    de Información Formulario para la solicitud de datos e información relevantes a las investigaciones Science Foundation under Grant No. 0948507." back up ↑ © Copyright 2018 San Juan Ultra (Mooklabs

  20. 33 CFR 110.240 - San Juan Harbor, P.R.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false San Juan Harbor, P.R. 110.240 Section 110.240 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.240 San Juan Harbor, P.R. (a) The anchorage grounds—(1...

  1. 33 CFR 110.240 - San Juan Harbor, P.R.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false San Juan Harbor, P.R. 110.240 Section 110.240 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.240 San Juan Harbor, P.R. (a) The anchorage grounds—(1...

  2. 33 CFR 110.240 - San Juan Harbor, P.R.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false San Juan Harbor, P.R. 110.240 Section 110.240 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.240 San Juan Harbor, P.R. (a) The anchorage grounds—(1...

  3. 33 CFR 110.240 - San Juan Harbor, P.R.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false San Juan Harbor, P.R. 110.240 Section 110.240 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.240 San Juan Harbor, P.R. (a) The anchorage grounds—(1...

  4. 33 CFR 110.240 - San Juan Harbor, P.R.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false San Juan Harbor, P.R. 110.240 Section 110.240 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.240 San Juan Harbor, P.R. (a) The anchorage grounds—(1...

  5. Pole of rotating analysis of present-day Juan de Fuca plate motion

    NASA Technical Reports Server (NTRS)

    Nishimura, C.; Wilson, D. S.; Hey, R. N.

    1984-01-01

    Convergence rates between the Juan de Fuca and North American plates are calculated by means of their relative, present-day pole of rotation. A method of calculating the propagation of errors in addition to the instantaneous poles of rotation is also formulated and applied to determine the Euler pole for Pacific-Juan de Fuca. This pole is vectorially added to previously published poles for North America-Pacific and 'hot spot'-Pacific to obtain North America-Juan de Fuca and 'hot spot'-Juan de Fuca, respectively. The errors associated with these resultant poles are determined by propagating the errors of the two summed angular velocity vectors. Under the assumption that hot spots are fixed with respect to a mantle reference frame, the average absolute velocity of the Juan de Puca plate is computed at approximately 15 mm/yr, thereby making it the slowest-moving of the oceanic plates.

  6. Una Visita al Viejo San Juan (A Visit to Old San Juan).

    ERIC Educational Resources Information Center

    Cabello, Victor; And Others

    Written in Spanish, this black and white illustrated booklet provides a tour of Old San Juan, Puerto Rico's oldest and most historic city. Brief historical information is provided on the Perro de San Jeronimo, a statue of a barking dog found in front of the Castillo; Plaza de Colon, a small plaza dedicated to Christopher Columbus; the Catedral de…

  7. 1. View of three detection radar (DR) antennas. DR 1 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. View of three detection radar (DR) antennas. DR 1 (structure no. 735) on left, DR 2 (structure no. 736) in center, and DR 3 (structure no. 737) looking north 30 degrees west, with tracking radar (large radome) and satcom (satellite communication) system in small radome in view between DR 2 and DR 3 antennae. - Clear Air Force Station, Ballistic Missile Early Warning System Site II, One mile west of mile marker 293.5 on Parks Highway, 5 miles southwest of Anderson, Anderson, Denali Borough, AK

  8. 33 CFR 165.758 - Security Zone; San Juan, Puerto Rico.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Security Zone; San Juan, Puerto Rico. (a) Location. Moving and fixed security zones are established 50... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Security Zone; San Juan, Puerto Rico. 165.758 Section 165.758 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND...

  9. 33 CFR 165.758 - Security Zone; San Juan, Puerto Rico.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Security Zone; San Juan, Puerto Rico. (a) Location. Moving and fixed security zones are established 50... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Security Zone; San Juan, Puerto Rico. 165.758 Section 165.758 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND...

  10. 33 CFR 165.758 - Security Zone; San Juan, Puerto Rico.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Security Zone; San Juan, Puerto Rico. (a) Location. Moving and fixed security zones are established 50... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Security Zone; San Juan, Puerto Rico. 165.758 Section 165.758 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND...

  11. 33 CFR 165.758 - Security Zone; San Juan, Puerto Rico.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Security Zone; San Juan, Puerto Rico. (a) Location. Moving and fixed security zones are established 50... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Security Zone; San Juan, Puerto Rico. 165.758 Section 165.758 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND...

  12. 33 CFR 165.758 - Security Zone; San Juan, Puerto Rico.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Security Zone; San Juan, Puerto Rico. (a) Location. Moving and fixed security zones are established 50... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Security Zone; San Juan, Puerto Rico. 165.758 Section 165.758 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND...

  13. 33 CFR 110.229 - Straits of Juan de Fuca, Wash.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Straits of Juan de Fuca, Wash. 110.229 Section 110.229 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.229 Straits of Juan de Fuca, Wash. (a) Anchorage...

  14. 33 CFR 110.229 - Straits of Juan de Fuca, Wash.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Straits of Juan de Fuca, Wash. 110.229 Section 110.229 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.229 Straits of Juan de Fuca, Wash. (a) Anchorage...

  15. 33 CFR 110.74c - Bahia de San Juan, PR.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Bahia de San Juan, PR. 110.74c Section 110.74c Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.74c Bahia de San Juan, PR. The waters of San Antonio...

  16. 33 CFR 110.74c - Bahia de San Juan, PR.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Bahia de San Juan, PR. 110.74c Section 110.74c Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.74c Bahia de San Juan, PR. The waters of San Antonio...

  17. 33 CFR 110.74c - Bahia de San Juan, PR.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Bahia de San Juan, PR. 110.74c Section 110.74c Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.74c Bahia de San Juan, PR. The waters of San Antonio...

  18. Juan's Dilemma: A New Twist on the Old Lemon Battery

    ERIC Educational Resources Information Center

    Hunt, Vanessa; Sorey, Timothy; Balandova, Evguenia; Palmquist, Bruce

    2010-01-01

    When life hands you lemons, make a battery! In this article, the authors describe an activity they refer to as "Juan's Dilemma," an extension of the familiar lemon-battery activity (Goodisman 2001). Juan's Dilemma integrates oxidation and reduction chemistry with circuit theory in a fun, real-world exercise. The authors designed this activity for…

  19. Hydrologic data from wells at or in the vicinity of the San Juan coal mine, San Juan County, New Mexico

    USGS Publications Warehouse

    Stewart, Anne M.; Thomas, Nicole

    2015-01-01

    In 2010, in cooperation with the Mining and Minerals Division (MMD) of the State of New Mexico Energy, Minerals and Natural Resources Department, the U.S. Geological Survey (USGS) initiated a 4-year assessment of hydrologic conditions at the San Juan coal mine (SJCM), located about 14 miles west-northwest of the city of Farmington, San Juan County, New Mexico. The mine produces coal for power generation at the adjacent San Juan Generating Station (SJGS) and stores coal-combustion byproducts from the SJGS in mined-out surface-mining pits. The purpose of the hydrologic assessment is to identify groundwater flow paths away from SJCM coal-combustion-byproduct storage sites that might allow metals that may be leached from coal-combustion byproducts to eventually reach wells or streams after regional dewatering ceases and groundwater recovers to predevelopment levels. The hydrologic assessment, undertaken between 2010 and 2013, included compilation of existing data. The purpose of this report is to present data that were acquired and compiled by the USGS for the SJCM hydrologic assessment.

  20. The Forts of Old San Juan: Guardians of the Caribbean. Teaching with Historic Places.

    ERIC Educational Resources Information Center

    Weltzin, Rosanna

    The massive masonry defenses of Old San Juan, Puerto Rico, which were begun in the 16th century, exist today as the oldest European-style fortifications within the territory of the United States. This lesson is based on the World Heritage Site nomination file and the National Park Service Handbook, "San Juan: The Forts of Old San Juan."…

  1. [Dr Stockmann and Dr Snow--two heroes of public health].

    PubMed

    Nylenna, Magne

    2003-12-23

    Dr Thomas Stockmann, the main character of An enemy of the people by Henrik Ibsen (1828-1906), has been described as a hero of public health. In spite of his idealism and high principles, he was, however, not able to do anything about the contaminated water supply of the baths in the town where he lived. Important differences may be noticed if we compare the fictional Dr Stockmann with Dr John Snow (1813-58), a real hero of public health famous for his handling of a cholera epidemic in London in 1854. While Dr Snow carried out extensive investigations of the relation between water supply and illness and still was humble when presenting his findings, the fictional Dr Stockmann took only one sample of water for examination and was bombastic in his conclusion. And while Dr Snow had a simple suggestion for solving the problem, Dr Stockmann seemed more eager to dramatize the situation. Scientific documentation and a practical attitude to problem solving continue to be important in order to achieve results in the field of public health.

  2. 33 CFR 167.1310 - In the Strait of Juan de Fuca: General.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY OFFSHORE TRAFFIC SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Pacific West Coast § 167.1310 In the Strait of Juan de Fuca: General. The traffic separation scheme in the Strait of Juan de Fuca consists of five parts: the western...

  3. 33 CFR 167.1310 - In the Strait of Juan de Fuca: General.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY OFFSHORE TRAFFIC SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Pacific West Coast § 167.1310 In the Strait of Juan de Fuca: General. The traffic separation scheme in the Strait of Juan de Fuca consists of five parts: the western...

  4. 33 CFR 167.1310 - In the Strait of Juan de Fuca: General.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY OFFSHORE TRAFFIC SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Pacific West Coast § 167.1310 In the Strait of Juan de Fuca: General. The traffic separation scheme in the Strait of Juan de Fuca consists of five parts: the western...

  5. 33 CFR 167.1310 - In the Strait of Juan de Fuca: General.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY OFFSHORE TRAFFIC SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Pacific West Coast § 167.1310 In the Strait of Juan de Fuca: General. The traffic separation scheme in the Strait of Juan de Fuca consists of five parts: the western...

  6. Progress in SLR-GPS co-location at San Juan (Argentina) station

    NASA Astrophysics Data System (ADS)

    Luis, Hernan; Rojas, Alvis; Adarvez, Sonia; Quinteros, Johana; Cobos, Pablo; Aracena, Andrés; Pacheco, Ana M.; Podestá, Ricardo; Actis, Eloy V.; Li, Jinzeng; Yin, Zhiqiang; Wang, Rui; Huang, Dongping; Márquez, Raúl

    2012-08-01

    From February, 2006, performing a Cooperation Agreement with National Astronomical Observatories of China (NAOC) of the Chinese Academy of Sciences (CAS), Observatorio Astronómico Félix Aguilar (OAFA) of Universidad Nacional de San Juan (UNSJ) is operating a SLR System (ILRS 7406 Station). From the beginning of 2012 a GPS Aztech - Micro Z CGRS is operative at the same place, which made the SLR - GPS co - location possible. The prior objective is to reach co - location between both techniques, so the Station became of 1st order in ITRF net. For that we study and adopt an appropriate strategy to select and place Survey Control Points that ensures higher precision in determination of 3D vectors between the selected reference point s. Afterwards we perform translocation tasks of receptor and antenna checking that the GPS verifies builder standards. Then we design and compensate survey control network, by means of software of our own draught. We expect to obtain definitive local ties with precision better than 3 mm, as suggested by IERS for co - located stations. There are very few stations with co - located spatial techniques in the Southern Hemisphere, so it is of great importance to have one in Argentina for improve our participation in IERS on the new realizations of ITRF from now on.

  7. 33 CFR 167.1302 - In the approaches to the Strait of Juan de Fuca: Southwestern approach.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... of Juan de Fuca: Southwestern approach. 167.1302 Section 167.1302 Navigation and Navigable Waters....1302 In the approaches to the Strait of Juan de Fuca: Southwestern approach. In the southwestern approach to the Strait of Juan de Fuca, the following are established: (a) A separation zone bounded by a...

  8. Tectonics and evolution of the Juan Fernandez microplate at the Pacific-Nazca-Antarctic triple junction

    NASA Technical Reports Server (NTRS)

    Anderson-Fontana, S.; Larson, R. L.; Engein, J. F.; Lundgren, P.; Stein, S.

    1986-01-01

    Magnetic and bathymetric profiles derived from the R/V Endeavor survey and focal mechanism studies for earthquakes on two of the Juan Fernandez microplate boundaries are analyzed. It is observed that the Nazca-Juan Fernandez pole is in the northern end of the microplate since the magnetic lineation along the East Ridge of the microplate fans to the south. The calculation of the relative motion of the Juan Fernandez-Pacific-Nazca-Antarctic four-plate system using the algorithm of Minster et al. (1974) is described. The development of tectonic and evolutionary models of the region is examined. The tectonic model reveals that the northern boundary of the Juan Fernandez microplate is a zone of compression and that the West Ridge and southwestern boundary are spreading obliquely; the evolutionary model relates the formation of the Juan Fernandez microplate to differential spreading rates at the triple junction.

  9. 33 CFR 167.1301 - In the approaches to the Strait of Juan de Fuca: Western approach.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... of Juan de Fuca: Western approach. 167.1301 Section 167.1301 Navigation and Navigable Waters COAST....1301 In the approaches to the Strait of Juan de Fuca: Western approach. In the western approach to the Strait of Juan de Fuca, the following are established: (a) A separation zone bounded by a line connecting...

  10. Juan Carlos D'Olivo: A portrait

    NASA Astrophysics Data System (ADS)

    Aguilar-Arévalo, Alexis A.

    2013-06-01

    This report attempts to give a brief bibliographical sketch of the academic life of Juan Carlos D'Olivo, researcher and teacher at the Instituto de Ciencias Nucleares of UNAM, devoted to advancing the fields of High Energy Physics and Astroparticle Physics in Mexico and Latin America.

  11. 77 FR 32989 - Notice of Inventory Completion: U.S. Department of Agriculture, San Juan National Forest, Durango...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-04

    ... Inventory Completion: U.S. Department of Agriculture, San Juan National Forest, Durango, CO, and University... the control of the U.S. Department of Agriculture, San Juan National Forest, Durango, CO, and in the... by the U.S. Department of Agriculture, San Juan National Forest in the Federal Register (73 FR 49485...

  12. Geothermal studies in the San Juan Basin and the Four Corners Area of the Colorado Plateau II. Steady-state models of the thermal source of the San Juan volcanic field

    NASA Astrophysics Data System (ADS)

    Reiter, Marshall; Clarkson, Gerry

    1983-01-01

    The increase of heat flow approaching the San Juan volcanic field depicts a smooth profile having a relatively large half width, perhaps 50-100 km. One may suggest thermal sources creating the observed anomaly at equivalent depths under, or in proximity to, the San Juan volcanic field. Although the cause of the increased heat flow approaching the San Juan field may be in part associated with more regional Southern Rocky Mountain tectonics; geologic, heat-flow, and seismic data support the idea of a separate thermal source associated with the San Juan volcanic field. It can be shown that cooling and solidification of very deep magma bodies (to 75 km) provide less heat than required by the observed anomaly. Replenishment of the thermal source causing the heat-flow anomaly is postulated. This replenishment is approximated in a limiting case by developing finite-difference steady-state models. The best models are consistent with a plume which rises from depths of at least 100 km to depths as shallow as 35 km, whose edge is about 10 km south of Durango.

  13. CHARACTERIZING THE ORGANIC MATTER IN SURFACE SEDIMENTS FROM THE SAN JUAN BAY ESTUARY.

    EPA Science Inventory

    The San Juan Bay Estuary (SJBE) is located on the north coast of Puerto Rico and includes the San Juan Bay, San José Lagoon, La Torrecilla Lagoon and Piñones Lagoon, as well as the Martín Peña and the Suárez Canals. The SJBE watershed has the highest...

  14. Characterizing the Organic Matter in Surface Sediments from the San Juan Bay Estuary,

    EPA Science Inventory

    The San Juan Bay Estuary (SJBE) is located on the north coast of Puerto Rico and includes the San Juan Bay, San José Lagoon, La Torrecilla Lagoon and Piñones Lagoon, as well as the Martín Peña and the Suárez Canals. The SJBE watershed has the highest...

  15. CHARACTERIZING THE ORGANIC MATTER IN SURFACE SEDIMENTS FROM THE SAN JUAN BAY ESTUARY

    EPA Science Inventory

    The San Juan Bay Estuary (SJBE) is located on the north coast of Puerto Rico and includes the San Juan Bay, San José Lagoon, La Torrecilla Lagoon and Piñones Lagoon, as well as the Martín Peña and the Suárez Canals. The SJBE watershed has the highest...

  16. Geologic map of the central San Juan caldera cluster, southwestern Colorado

    USGS Publications Warehouse

    Lipman, Peter W.

    2006-01-01

    The San Juan Mountains are the largest erosional remnant of a composite volcanic field that covered much of the southern Rocky Mountains in middle Tertiary time. The San Juan field consists mainly of intermediate-composition lavas and breccias, erupted about 35-30 Ma from scattered central volcanoes (Conejos Formation) and overlain by voluminous ash-flow sheets erupted from caldera sources. In the central San Juan Mountains, eruption of at least 8,800 km3 of dacitic-rhyolitic magma as nine major ash flow sheets (individually 150-5,000 km3) was accompanied by recurrent caldera subsidence between 28.3 Ma and about 26.5 Ma. Voluminous andesitic-dacitic lavas and breccias erupted from central volcanoes prior to the ash-flow eruptions, and similar lava eruptions continued within and adjacent to the calderas during the period of more silicic explosive volcanism. Exposed calderas vary in size from 10 to 75 km in maximum dimension; the largest calderas are associated with the most voluminous eruptions.

  17. LOD First Estimates In 7406 SLR San Juan Argentina Station

    NASA Astrophysics Data System (ADS)

    Pacheco, A.; Podestá, R.; Yin, Z.; Adarvez, S.; Liu, W.; Zhao, L.; Alvis Rojas, H.; Actis, E.; Quinteros, J.; Alacoria, J.

    2015-10-01

    In this paper we show results derived from satellite observations at the San Juan SLR station of Felix Aguilar Astronomical Observatory (OAFA). The Satellite Laser Ranging (SLR) telescope was installed in early 2006, in accordance with an international cooperation agreement between the San Juan National University (UNSJ) and the Chinese Academy of Sciences (CAS). The SLR has been in successful operation since 2011 using NAOC SLR software for the data processing. This program was designed to calculate satellite orbits and station coordinates, however it was used in this work for the determination of LOD (Length Of Day) time series and Earth Rotation speed.

  18. Razorback sucker movements and habitat use in the San Juan River inflow, Lake Powell, Utah, 1995-1997

    USGS Publications Warehouse

    Karp, C.A.; Mueller, G.

    2002-01-01

    Seventeen subadult, hatchery-reared razorback suckers (Xyrauchen texanus; (x̄ = 456 mm total length) were implanted with sonic transmitters and tracked for 23 months in the lower 89.6 km of the San Juan River (San Juan arm of Lake Powell, Utah). Fish were released at 2 sites, and 9 made extensive up-and downstream movements (x = 47.8 km; contact was lost with 4, and 4 others presumably died or lost their transmitters). The San Juan arm is primarily inundated canyon; however, most fish contacts occurred in shallow coves and shoreline with thick stands of flooded salt cedar in the upper inflow area. Eight fish frequented the Piute Farms river/lake mixing zone, and at least 4 moved upstream into the San Juan River. Seven fish were found in 2 aggregations in spring (3 fish in Neskahi Bay in 1996 and 4 fish just downstream of Piute Farms in 1997), and these may have been associated with spawning activity. Continued presence of razorback suckers in the Piute Farms area and lower San Juan River suggests the San Juan inflow to Lake Powell could be used as an alternate stocking site for reintroduction efforts.

  19. The San Juan Delta, Colombia: tides, circulations, and salt dispersion

    NASA Astrophysics Data System (ADS)

    Restrepo, Juan D.; Kjerfve, Björn

    2002-05-01

    The San Juan River delta (Colombia) with an area of 800 km 2 is the largest delta environment on the Pacific coast of South America. It consists of active distributaries maintained by an average discharge of 2500 m 3 s -1, is tide dominated, and has relatively narrow estuarine mixing zones <17 km wide and typically ˜7 km wide. Water level and current time series in two distributary mouths indicate that the tide is semidiurnal with a form number 0.1-0.2 and a mean range of 3 m. Processes at tidal frequencies explain 75-95% of the water level variability with the remaining low-frequency variability attributed to meteorological forcing and river processes. The tidal phase for the main diurnal and semidiurnal constituents progress from north to south along the coast. Only the southernmost distributary experiences significant tidal asymmetry as a result of strong river discharge and shallow depths. In the northernmost distributary, shallow water constituents are insignificant. Tidal currents were more semidiurnal than the water level, with form number 0.09-0.13. Tidal ellipses indicated that currents were aligned with the channels and mean amplitudes <1 m s -1. In the delta distributaries, circulation modes varied from seaward flow at all depths during intermediate runoff conditions to gravitational circulation during rising and high discharge periods. In San Juan and Chavica distributaries, the currents were ebb-directed, while in Charambirá they were flood-directed. The circulation appears to be controlled by the morphology of the distributaries, which were weakly stratified and only sometimes moderately stratified. The net salt transport was directed seaward in San Juan and Charambirá, and landward at Chavica, indicating an imbalance in the salt budget, and signifying non-steady state behavior. The net longitudinal salt flux in the San Juan delta is largely a balance between ebb-directed advective flux, and flood-directed tidal sloshing. Along the distributary

  20. SAN JUAN BAY ESTUARY PROGRAM IMPLEMENTATION REVIEW ATTACHMENTS

    EPA Science Inventory

    A compilation of attachments referenced in the San Juan Bay Estuary Program Implementation Review (2004). Materials include, entity reports, water and sediment quality action plans, progress reports, correspondence with local municipalities and Puerto Rican governmental agencies,...

  1. RadNet Air Data From San Juan, PR

    EPA Pesticide Factsheets

    This page presents radiation air monitoring and air filter analysis data for San Juan, PR from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

  2. 77 FR 33239 - Prairie Stewardship Plan/Environmental Impact Statement, San Juan Island National Historical Park

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-05

    ... Stewardship Plan/Environmental Impact Statement, San Juan Island National Historical Park AGENCY: National... Prairie Stewardship Plan, San Juan Island National Historical Park, Washington. SUMMARY: Pursuant to the... initiating the preparation of an Environmental Impact Statement (EIS) for a Prairie Stewardship Plan, as...

  3. 78 FR 72060 - Chimney Rock National Monument Management Plan; San Juan National Forest; Colorado

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-02

    ..., as well as objects of deep cultural and educational value. The plan will also provide for continued... Ranger District office in Pagosa Springs, Colorado, and on the San Juan National Forest Web site at www..., direct mailings, emails, and will be posted on the San Juan National Forest Web site. It is important...

  4. Physiography and Quaternary geology of the San Juan Mountains, Colorado

    USGS Publications Warehouse

    Atwood, Wallace W.; Mather, Kirtley F.

    1932-01-01

    appeared from time to time as folios"' of the Geologic Atlas and reports on the economic geology of the mining districts, published by the United States Geological Survey between 1899 and 1910. Gradually the concept of the geologic problems was changed. Instead of considering individual mining districts as the units of investigation it became apparent that the San Juan region must itself be the unit. In 1908 Mr. Cross drafted plans for the completion of the San Juan studies on this enlarged basis. His aim was to arrange for the publication of papers on different subjects rather than one huge monograph on the region as a whole.

  5. 33 CFR 161.55 - Vessel Traffic Service Puget Sound and the Cooperative Vessel Traffic Service for the Juan de...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Sound and the Cooperative Vessel Traffic Service for the Juan de Fuca Region. 161.55 Section 161.55... the Juan de Fuca Region. The Vessel Traffic Service Puget Sound area consists of the navigable waters... International Boundary through the waters known as the Strait of Juan de Fuca, Haro Strait, Boundary Pass, and...

  6. 33 CFR 161.55 - Vessel Traffic Service Puget Sound and the Cooperative Vessel Traffic Service for the Juan de...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Sound and the Cooperative Vessel Traffic Service for the Juan de Fuca Region. 161.55 Section 161.55... the Juan de Fuca Region. The Vessel Traffic Service Puget Sound area consists of the navigable waters... International Boundary through the waters known as the Strait of Juan de Fuca, Haro Strait, Boundary Pass, and...

  7. ORAC-DR -- Programmer's Guide

    NASA Astrophysics Data System (ADS)

    Jenness, Tim; Economou, Frossie; Cavanagh, Brad

    ORAC-DR is a general purpose automatic data reduction pipeline environment. This document describes how to modify data reduction recipes and how to add new instruments. For a general overview of ORAC-DR see SUN/230. For specific information on how to reduce the data for a particular instrument, please consult the appropriate ORAC-DR instrument guide.

  8. The San Juan Canyon, southeastern Utah: A geographic and hydrographic reconnaissance

    USGS Publications Warehouse

    Miser, Hugh D.

    1924-01-01

    This report, which describes the San Juan Canyon, San Juan River and the tributary streams and the geography and to some extent the geology of the region, presents information obtained by me during the descent of the river with the Trimble party in 1921. The exploration of the canyon, which was financed jointly by the United States Geological Survey and the Southern California Edison Co., had as its primary object the mapping and study of the San Juan in connection with proposed power and storage projects along this and Colorado rivers.1 The exploration party was headed by K. W. Thimble, topographic engineer of the United States Geological Survey. Other members of the party were Robert N. Allen, Los Angeles, Calif., recorder; H. E. Blake, jr., Monticello, Utah, and Hugh Hyde, Salt Lake City, Utah, rodmen; Bert Loper, Green River, Utah, boatman; Heber Christensen, Moab, Utah, cook; and H. D. Miser, geologist. Wesley Oliver, of Mexican Hat, Utah, served as packer for the party and brought mail and provisions by pack train twice a month to specified accessible places west of Goodridge.

  9. Gaia DR2 documentation

    NASA Astrophysics Data System (ADS)

    van Leeuwen, F.; de Bruijne, J. H. J.; Arenou, F.; Bakker, J.; Blomme, R.; Busso, G.; Cacciari, C.; Castañeda, J.; Cellino, A.; Clotet, M.; Comoretto, G.; Eyer, L.; González-Núñez, J.; Guy, L.; Hambly, N.; Hobbs, D.; van Leeuwen, M.; Luri, X.; Manteiga, M.; Pourbaix, D.; Roegiers, T.; Salgado, J.; Sartoretti, P.; Tanga, P.; Ulla, A.; Utrilla Molina, E.; Abreu, A.; Altmann, M.; Andrae, R.; Antoja, T.; Audard, M.; Babusiaux, C.; Bailer-Jones, C. A. L.; Barache, C.; Bastian, U.; Beck, M.; Berthier, J.; Bianchi, L.; Biermann, M.; Bombrun, A.; Bossini, D.; Breddels, M.; Brown, A. G. A.; Busonero, D.; Butkevich, A.; Cantat-Gaudin, T.; Carrasco, J. M.; Cheek, N.; Clementini, G.; Creevey, O.; Crowley, C.; David, M.; Davidson, M.; De Angeli, F.; De Ridder, J.; Delbò, M.; Dell'Oro, A.; Diakité, S.; Distefano, E.; Drimmel, R.; Durán, J.; Evans, D. W.; Fabricius, C.; Fabrizio, M.; Fernández-Hernández, J.; Findeisen, K.; Fleitas, J.; Fouesneau, M.; Galluccio, L.; Gracia-Abril, G.; Guerra, R.; Gutiérrez-Sánchez, R.; Helmi, A.; Hernandez, J.; Holl, B.; Hutton, A.; Jean-Antoine-Piccolo, A.; Jevardat de Fombelle, G.; Joliet, E.; Jordi, C.; Juhász, Á.; Klioner, S.; Löffler, W.; Lammers, U.; Lanzafame, A.; Lebzelter, T.; Leclerc, N.; Lecoeur-Taïbi, I.; Lindegren, L.; Marinoni, S.; Marrese, P. M.; Mary, N.; Massari, D.; Messineo, R.; Michalik, D.; Mignard, F.; Molinaro, R.; Molnár, L.; Montegriffo, P.; Mora, A.; Mowlavi, N.; Muinonen, K.; Muraveva, T.; Nienartowicz, K.; Ordenovic, C.; Pancino, E.; Panem, C.; Pauwels, T.; Petit, J.; Plachy, E.; Portell, J.; Racero, E.; Regibo, S.; Reylé, C.; Rimoldini, L.; Ripepi, V.; Riva, A.; Robichon, N.; Robin, A.; Roelens, M.; Romero-Gómez, M.; Sarro, L.; Seabroke, G.; Segovia, J. C.; Siddiqui, H.; Smart, R.; Smith, K.; Sordo, R.; Soria, S.; Spoto, F.; Stephenson, C.; Turon, C.; Vallenari, A.; Veljanoski, J.; Voutsinas, S.

    2018-04-01

    The second Gaia data release, Gaia DR2, encompasses astrometry, photometry, radial velocities, astrophysical parameters (stellar effective temperature, extinction, reddening, radius, and luminosity), and variability information plus astrometry and photometry for a sample of pre-selected bodies in the solar system. The data collected during the first 22 months of the nominal, five-year mission have been processed by the Gaia Data Processing and Analysis Consortium (DPAC), resulting into this second data release. A summary of the release properties is provided in Gaia Collaboration et al. (2018b). The overall scientific validation of the data is described in Arenou et al. (2018). Background information on the mission and the spacecraft can be found in Gaia Collaboration et al. (2016), with a more detailed presentation of the Radial Velocity Spectrometer (RVS) in Cropper et al. (2018). In addition, Gaia DR2 is accompanied by various, dedicated papers that describe the processing and validation of the various data products. Four more Gaia Collaboration papers present a glimpse of the scientific richness of the data. In addition to this set of refereed publications, this documentation provides a detailed, complete overview of the processing and validation of the Gaia DR2 data. Gaia data, from both Gaia DR1 and Gaia DR2, can be retrieved from the Gaia archive, which is accessible from https://archives.esac.esa.int/gaia. The archive also provides various tutorials on data access and data queries plus an integrated data model (i.e., description of the various fields in the data tables). In addition, Luri et al. (2018) provide concrete advice on how to deal with Gaia astrometry, with recommendations on how best to estimate distances from parallaxes. The Gaia archive features an enhanced visualisation service which can be used for quick initial explorations of the entire Gaia DR2 data set. Pre-computed cross matches between Gaia DR2 and a selected set of large surveys are

  10. 33 CFR 167.1303 - In the approaches to the Strait of Juan de Fuca: Precautionary area “JF.”

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... of Juan de Fuca: Precautionary area âJF.â 167.1303 Section 167.1303 Navigation and Navigable Waters....1303 In the approaches to the Strait of Juan de Fuca: Precautionary area “JF.” In the approaches to the Strait of Juan de Fuca, precautionary area “JF” is established and is bounded by a line connecting the...

  11. Dr. Wernher Von Braun

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Dr. Thomas Paine, Deputy Administrator of the National Aeronautics and Space Administration, examines an ordinary man's shoe outfitted for use in the Saturn I workshop. Pictured from the left in the Saturn I workshop mockup are William Brooksbank, propulsion and vehicle engineering laboratory; Dr. Paine; Dr. Wernher Von Braun, Marshall Center director; Colonel Clare F. Farley, Executive Officer in the Office Of The Administrator; and Charles J. Donlan, Deputy Associate Administrator for Manned Space Flight, Technical. the shoe Dr. Paine is holding has a unique fastener built into the sole to allow an astronaut to move about on the workshop floor and to remain in one position if he desires.

  12. 75 FR 41819 - Reorganization/Expansion of Foreign-Trade Zone 61 San Juan, Puerto Rico, Area

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-19

    ... Foreign-Trade Zone 61 San Juan, Puerto Rico, Area Pursuant to its authority under the Foreign-Trade Zones... the following Order: Whereas, the Puerto Rico Trade and Export Company, grantee of Foreign-Trade Zone..., Puerto Rico, area within and adjacent to the San Juan Customs and Border Protection port of entry (FTZ...

  13. 78 FR 61958 - San Juan County Historical Society; Notice of Preliminary Determination of A Qualifying Conduit...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-08

    ... Historical Society; Notice of Preliminary Determination of A Qualifying Conduit Hydropower Facility and Soliciting Comments and Motions To Intervene On September 20, 2013, San Juan County Historical Society filed... County, Colorado. Applicant Contact: Beverly Rich, San Juan County Historical Society, P.O. Box 154...

  14. Dr. Daniel Carter

    NASA Technical Reports Server (NTRS)

    1998-01-01

    Dr. Daniel Carter, president of New Century Pharmaceuticals in Huntsville, Al, is one of three principal investigators in NASA's microgravity protein crystal growth program. Dr. Carter's experties is in albumins. Albumins are proteins in the bloodstream that transport materials, drugs, nutrients, and wastes. Photo credit: NASA/Marshall Space Flight Center

  15. Dual Agonist Surrobody Simultaneously Activates Death Receptors DR4 and DR5 to Induce Cancer Cell Death.

    PubMed

    Milutinovic, Snezana; Kashyap, Arun K; Yanagi, Teruki; Wimer, Carina; Zhou, Sihong; O'Neil, Ryann; Kurtzman, Aaron L; Faynboym, Alexsandr; Xu, Li; Hannum, Charles H; Diaz, Paul W; Matsuzawa, Shu-ichi; Horowitz, Michael; Horowitz, Lawrence; Bhatt, Ramesh R; Reed, John C

    2016-01-01

    Death receptors of the TNF family are found on the surface of most cancer cells and their activation typically kills cancer cells through the stimulation of the extrinsic apoptotic pathway. The endogenous ligand for death receptors 4 and 5 (DR4 and DR5) is TNF-related apoptosis-inducing ligand, TRAIL (Apo2L). As most untransformed cells are not susceptible to TRAIL-induced apoptosis, death receptor activators have emerged as promising cancer therapeutic agents. One strategy to stimulate death receptors in cancer patients is to use soluble human recombinant TRAIL protein, but this agent has limitations of a short half-life and decoy receptor sequestration. Another strategy that attempted to evade decoy receptor sequestration and to provide improved pharmacokinetic properties was to generate DR4 or DR5 agonist antibodies. The resulting monoclonal agonist antibodies overcame the limitations of short half-life and avoided decoy receptor sequestration, but are limited by activating only one of the two death receptors. Here, we describe a DR4 and DR5 dual agonist produced using Surrobody technology that activates both DR4 and DR5 to induce apoptotic death of cancer cells in vitro and in vivo and also avoids decoy receptor sequestration. This fully human anti-DR4/DR5 Surrobody displays superior potency to DR4- and DR5-specific antibodies, even when combined with TRAIL-sensitizing proapoptotic agents. Moreover, cancer cells were less likely to acquire resistance to Surrobody than either anti-DR4 or anti-DR5 monospecific antibodies. Taken together, Surrobody shows promising preclinical proapoptotic activity against cancer cells, meriting further exploration of its potential as a novel cancer therapeutic agent. ©2015 American Association for Cancer Research.

  16. Dual agonist Surrobody™ simultaneously activates death receptors DR4 and DR5 to induce cancer cell death

    PubMed Central

    Milutinovic, Snezana; Kashyap, Arun K.; Yanagi, Teruki; Wimer, Carina; Zhou, Sihong; O' Neil, Ryann; Kurtzman, Aaron L.; Faynboym, Alexsandr; Xu, Li; Hannum, Charles H.; Diaz, Paul W.; Matsuzawa, Shu-ichi; Horowitz, Michael; Horowitz, Lawrence; Bhatt, Ramesh R.; Reed, John C.

    2015-01-01

    Death receptors of the Tumor Necrosis Factor (TNF) family are found on surface of most cancer cells and their activation typically kills cancer cells through the stimulation of the extrinsic apoptotic pathway. The endogenous ligand for death receptors-4 and -5 (DR4 and DR5) is Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand, TRAIL (Apo2L). Since most untransformed cells are not susceptible to TRAIL-induced apoptosis, death receptor activators have emerged as promising cancer therapeutic agents. One strategy to stimulate death receptors in cancer patients is to use soluble human recombinant TRAIL protein, but this agent has limitations of a short half-life and decoy receptor sequestration. Another strategy that attempted to evade decoy receptor sequestration and to provide improved pharmacokinetic properties was to generate DR4 or DR5 agonist antibodies. The resulting monoclonal agonist antibodies overcame the limitations of short half-life and avoided decoy receptor sequestration, but are limited by activating only one of the two death receptors. Here, we describe a DR4 and DR5 dual agonist produced using Surrobody™ technology that activates both DR4 and DR5 to induce apoptotic death of cancer cells in vitro and in vivo and also avoids decoy receptor sequestration. This fully human anti-DR4/DR5 Surrobody displays superior potency to DR4- and DR5-specific antibodies, even when combined with TRAIL-sensitizing pro-apoptotic agents. Moreover, cancer cells were less likely to acquire resistance to Surrobody than either anti-DR4 or anti-DR5 mono-specific antibodies. Taken together, Surrobody shows promising preclinical pro-apoptotic activity against cancer cells, meriting further exploration of its potential as a novel cancer therapeutic agent. PMID:26516157

  17. Oligonucleotide-genotyping as a method of detecting the HLA-DR2 (DRw15)-Dw2, -DR2 (DRw15)-Dw12, -DR4-Dw15, and -DR4-D"KT2" haplotypes in the Japanese population.

    PubMed

    Obata, F; Ito, I; Kaneko, T; Ohkubo, M; Ishimoto, A L; Abe, A; Kashiwagi, N

    1989-05-01

    We synthesized pairs of four different oligonucleotides, F22, F29, F42, and F158, to analyse the HLA-DR2 (DRw15) and -DR4 haplotypes in the Japanese population. After enzymatically amplifying the HLA-DRB1 gene, we hybridized the oligonucleotide probes with DNA extracted from 42 donors. Hybridization was completed between F22 and the DNA of haplotype DR2 (DRw15)-Dw2, between F29 and the DNA of DR2 (DRw15)-Dw12, between F42 and the DNA of DR4-D"KT2", and between F158 and the DNA of DR4-Dw15. In keeping with the nucleotide sequences of the probes, F29 hybridized also with DNA from the DR9-Dw23 haplotype and F158 with that from some of the DRw8 haplotypes (DRw8-Dw8.3) in the Japanese population. Results of this study demonstrate that the four oligonucleotides make useful probes for detecting the haplotypes above.

  18. 5. View of middle DR 2 antenna with DR 1 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. View of middle DR 2 antenna with DR 1 antenna in background. Photograph shows on left side at bottom foundation berm and along right side bottom stanchion concrete foundations at bottom structural steel assembly. - Clear Air Force Station, Ballistic Missile Early Warning System Site II, One mile west of mile marker 293.5 on Parks Highway, 5 miles southwest of Anderson, Anderson, Denali Borough, AK

  19. Large Customers (DR Sellers)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kiliccot, Sila

    2011-10-25

    State of the large customers for demand response integration of solar and wind into electric grid; openADR; CAISO; DR as a pseudo generation; commercial and industrial DR strategies; California regulations

  20. 33 CFR 162.260 - Channel leading to San Juan Harbor, P.R.; use, administration, and navigation.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Channel leading to San Juan Harbor, P.R.; use, administration, and navigation. 162.260 Section 162.260 Navigation and Navigable... WATERWAYS NAVIGATION REGULATIONS § 162.260 Channel leading to San Juan Harbor, P.R.; use, administration...

  1. 33 CFR 162.260 - Channel leading to San Juan Harbor, P.R.; use, administration, and navigation.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Channel leading to San Juan Harbor, P.R.; use, administration, and navigation. 162.260 Section 162.260 Navigation and Navigable... WATERWAYS NAVIGATION REGULATIONS § 162.260 Channel leading to San Juan Harbor, P.R.; use, administration...

  2. Dr. von Braun With Management Team

    NASA Technical Reports Server (NTRS)

    1961-01-01

    Dr. von Braun is shown in this photograph, which was probably taken in the early 1960s, with members of his management team. Pictured from left to right are, Werner Kuers, Director of the Manufacturing Engineering Division; Dr. Walter Haeussermarn, Director of the Astrionics Division; Dr. William Mrazek, Propulsion and Vehicle Engineering Division; Dr. von Braun; Dieter Grau, Director of the Quality Assurance Division; Dr. Oswald Lange, Director of the Saturn Systems Office; and Erich Neubert , Associate Deputy Director for Research and Development.

  3. Carbon storage and greenhouse gas fluxes in the San Juan ...

    EPA Pesticide Factsheets

    Mangrove systems are known carbon (C) and greenhouse gas (GHG) sinks, but this function may be affected by global change drivers that include (but are not limited to) eutrophication, climate change, species composition shifts, and hydrological changes. In Puerto Rico’s San Juan Bay Estuary, mangrove wetlands are characterized by anthropogenic impacts, particularly tidal restriction due to infilling of the Martin Pena Canal and eutrophication. The objective of our research is to measure carbon sequestration and carbon dioxide (CO2), methane (CH4), and nitrous oxide (N2O) fluxes in the San Juan Bay Estuary to understand the sustainability and role in global climate of this urban mangrove ecosystem. Cores for C sequestration measurements were collected and GHG fluxes were measured during rainy and dry seasons at 5 sites along a gradient of development and nitrogen loading in the San Juan Bay Estuary. At each site, paired GHG flux measurements were performed for mangrove wetland soil and estuarine water using static and floating chambers. Our results suggest a positive relationship between urban development and CH4 and N2O emissions, and demonstrate that in this system, estuarine waters are a major methane source. In addition to providing characterization of GHG fluxes in an urban subtropical estuary, these data provide a baseline against which future states of the estuary (after planned hydrological restoration has been implemented) may be compared. Thi

  4. Dr. Faustus: Theist or Atheist?

    ERIC Educational Resources Information Center

    Karim, Shah Mohammad Sanaul; Fathema, Fawzia; Hakim, Abdul

    2015-01-01

    Dr. Faustus is the greatest but the most controversial of Marlowe's plays. Among the causes of controversy, whether Dr. Faustus is an atheist or theist deserves utmost attention. This paper is intended to deal with the issue. Though at various stages of the development of the action, Dr. Faustus abjures Trinity, resorts to necromancy, becomes…

  5. Model Simulations of Waves in Hurricane Juan

    NASA Astrophysics Data System (ADS)

    Perrie, W.; Toulany, B.; Padilla-Hernandez, R.; Hu, Y.; Smith, P.; Zhang, W.; Zou, Q.; Ren, X.

    2004-05-01

    Hurricane Juan made landfall at 0300 UTC near Halifax Nova Scotia. This was a category 2 hurricane with winds of 44 m/s, the largest storm to pass over these coastal areas in several decades. Associated high ocean waves were experienced in coastal waters, from Peggy's Cove to Sheet Harbour, growing to epic proportions on the Scotian Shelf, and exceeding the 100-year return wave based on the present climatology. As part of the GoMOOS program (Gulf of Maine Ocean Observing System, www.gomoos.org), winds from the USA Navy COAMPS (Coupled Ocean Atmosphere Model Prediction System) were used to evaluate and compare three widely-used third generation numerical wave models, SWAN, WAM and WaveWatch-III (hereafter WW3) for accuracy, with in situ measurements. Model comparisons consist of a set of composite model systems, respectively nesting WAM, WW3 and SWAN in WAM and WW3. We report results from the intermediate-resolution grid for Hurricane Juan. Wave measurements were made using four operational deep-water buoys (C44258, C44142, C44137, 44005), by a conventional directional wave rider (DWR) moored offshore from Lunenburg Bay, and also by two acoustic Doppler current profiler (ADCP) located (1) near an oil rig on Sable Island Bank, in relatively shallow water, and (2) near the outer boundary of Lunenburg Bay. We discuss the reliability of DWR wave data compared to ADCP wave data. We show that all models provide reliable hindcasts for significant wave height (Hs) and for peak period (Tp) for Juan, although a clear under-estimation of Hs at the peak of the storm is evident, compared to observations. A feature in the COAMPS storm simulation is that the storm track appears to be slightly to the east of that of Quikscat scatterometer data. Comparisons between models and 2-dimensional wave spectra are presented. Preliminary results suggest that the recently released upgrade to the WW3 model shows slightly enhanced skill compared to the other models.

  6. INVENTION IS NOT AN OPTION

    PubMed Central

    Comedy, Yolanda L.; Gilbert, Juan E.; Pun, Suzie H.

    2017-01-01

    Inventors help solve all kinds of problems. The AAAS-Lemelson Invention Ambassador program celebrates inventors who have an impact on global challenges, making our communities and the globe better, one invention at a time. In this paper, we introduce two of these invention ambassadors: Dr. Suzie Pun and Dr. Juan Gilbert. Dr. Suzie Pun is the Robert F. Rushmer Professor of Bioengineering, an adjunct professor of chemical engineering, and a member of the Molecular Engineering and Sciences Institute at the University of Washington. Dr. Juan Gilbert is the Andrew Banks Family Preeminence Endowed Professor and chair of the Computer & Information Science & Engineering Department at the University of Florida. Both have a passion for solving problems and are dedicated to teaching their students to change the world. PMID:29527271

  7. 46 CFR 7.145 - Strait of Juan de Fuca, Haro Strait and Strait of Georgia WA.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 1 2011-10-01 2011-10-01 false Strait of Juan de Fuca, Haro Strait and Strait of Georgia WA. 7.145 Section 7.145 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Pacific Coast § 7.145 Strait of Juan de Fuca, Haro Strait and Strait...

  8. 46 CFR 7.145 - Strait of Juan de Fuca, Haro Strait and Strait of Georgia WA.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Strait of Juan de Fuca, Haro Strait and Strait of Georgia WA. 7.145 Section 7.145 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Pacific Coast § 7.145 Strait of Juan de Fuca, Haro Strait and Strait...

  9. Hydrothermal deposition on the Juan de Fuca Ridge over multiple glacial-interglacial cycles

    NASA Astrophysics Data System (ADS)

    Costa, Kassandra M.; McManus, Jerry F.; Middleton, Jennifer L.; Langmuir, Charles H.; Huybers, Peter J.; Winckler, Gisela; Mukhopadhyay, Sujoy

    2017-12-01

    Hydrothermal systems play an important role in modern marine chemistry, but little is known about how they may have varied on 100,000 year timescales. Here we present high-resolution records of non-lithogenic metal fluxes within sediment cores covering the last 500,000 years of hydrothermal deposition on the flanks of the Juan de Fuca Ridge. Six adjacent, gridded cores were analyzed by x-ray fluorescence for Fe, Mn, and Cu concentrations, corrected for lithogenic inputs with Ti, and normalized to excess initial 230Th to generate non-lithogenic metal flux records that provide the longest orbitally resolved reconstructions of hydrothermal activity currently available. Fe fluxes vary with global sea level over the last two glacial cycles, suggesting higher hydrothermal deposition during interglacial periods. The observed negative relationship between Fe and Mn indicates variable sediment redox conditions and diagenetic remobilization of sedimentary Mn over time. Thus, Mn fluxes may not be a reliable indicator for hydrothermal activity in the Juan de Fuca Ridge sediment cores. Cu fluxes show substantial high-frequency variability that may be linked to changes in vent temperature related to increased magmatic production during glacial periods. Deglacial hydrothermal peaks on the Juan de Fuca Ridge are consistent with previously published records from the Mid-Atlantic Ridge and the East Pacific Rise. Moreover, on the Juan de Fuca Ridge, the deglacial peaks in hydrothermal activity are followed by relatively high hydrothermal fluxes throughout the ensuing interglacial periods relative to the previous glacial period.

  10. Multimedia Data Capture with Multicast Dissemination for Online Distance Learning

    DTIC Science & Technology

    2001-12-01

    Juan Gril and Dr. Don Brutzman to wrap the multiple videos in a user- friendly environment. The web pages also contain the original PowerPoint...this CD, Juan Gril , a volunteer for the Siggraph 2001 Online Committee, created web pages that match the style and functionality desired by the...leader. The Committee for 2001 consisted of Don Brutzman, Stephen. Matsuba, Mike Collins, Allen Dutton, Juan Gril , Mike Hunsberger, Jerry Isdale

  11. [The medical world of Juan Gil de Zamora's Historia Naturalis (ca. 1275-1296)].

    PubMed

    García Ballester, L; Domínguez, A

    1994-01-01

    The article describes the authors and works which were quoted by the Franciscan Juan Gil de Zamora in his Historia naturalis, a scientific encyclopaedia written between c. 1275 and before 1296, probably in the Franciscan monastery of Zamora (Kingdom of Castille). Juan Gil made wide use of the Avicenna's Canon, Gilbertus de Aquila (Anglicus)'s Compendium medicine, and Salernitan medical literature. His work contributed to the diffusion of these medical authors and works throughout the Christian intellectual milieu of late medieval Castille. This diffusion was not without problems.

  12. 78 FR 28800 - Foreign-Trade Zone 61-San Juan, Puerto Rico; Application for Subzone; Parapiezas Corporation; San...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-16

    ..., Puerto Rico; Application for Subzone; Parapiezas Corporation; San Juan, Puerto Rico An application has been submitted to the Foreign-Trade Zones Board (the Board) by the Puerto Rico Trade & Export Company... located in San Juan, Puerto Rico. The application was submitted pursuant to the provisions of the Foreign...

  13. 78 FR 34125 - Notice of Inventory Completion: U.S. Department of Agriculture, Forest Service, San Juan National...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-06

    ... DEPARTMENT OF THE INTERIOR National Park Service [NPS-WASO-NAGPRA-13011; PPWOCRADN0-PCU00RP14.R50000] Notice of Inventory Completion: U.S. Department of Agriculture, Forest Service, San Juan National... of Agriculture (USDA), Forest Service, San Juan National Forest has completed an inventory of human...

  14. The green areas of San Juan, Puerto Rico

    Treesearch

    O.M. Ramos-Gonzalez

    2014-01-01

    Green areas, also known as green infrastructure or urban vegetation, are vital to urbanites for their critical roles in mitigating urban heat island effects and climate change and for their provision of multiple ecosystem services and aesthetics. Here, I provide a high spatial resolution snapshot of the green cover distribution of the city of San Juan, Puerto Rico, by...

  15. Enrico Fermi Awards Ceremony for Dr. Mildred S. Dresselhaus and Dr. Burton Richter, May 2012 (Presentations, including remarks by Energy Secretary, Dr. Steven Chu)

    ScienceCinema

    Chu, Steven [Dept. of Energy (DOE), Washington DC (United States)

    2018-06-12

    The Fermi Award is a Presidential award and is one of the oldest and most prestigious science and technology honors bestowed by the U.S. Government. On May 7, 2012 it was conferred upon two exceptional scientists: Dr. Mildred Dresselhaus, 'for her scientific leadership, her major contributions to science and energy policy, her selfless work in science education and the advancement of diversity in the scientific workplace, and her highly original and impactful research,' and Dr. Burton Richter, 'for the breadth of his influence in the multiple disciplines of accelerator physics and particle physics, his profound scientific discoveries, his visionary leadership as SLAC Director, his leadership of science, and his notable contributions in energy and public policy.' Dr. John Holder, Director of the White House Office of Science and Technology Policy, opened the ceremony, and Dr. Bill Brinkman, Director of DOE's Office of Science introduced the main speaker, Dr. Steven Chu, U.S. Energy Secretary.

  16. Carbon storage and greenhouse gas fluxes in the San Juan ...

    EPA Pesticide Factsheets

    Mangrove systems are known carbon (C) and greenhouse gas (GHG) sinks, but this function may be affected by global change drivers that include (but are not limited to) eutrophication, climate change, species composition shifts, and hydrological changes. In Puerto Rico’s San Juan Bay Estuary, mangrove wetlands are characterized by anthropogenic impacts, particularly tidal restriction due to infilling of the Martin Pena Canal and eutrophication. The objective of our research is to measure carbon sequestration and carbon dioxide (CO2), methane (CH4), and nitrous oxide (N2O) fluxes in the San Juan Bay Estuary to understand the sustainability and role in global climate of this urban mangrove ecosystem. Cores for C sequestration measurements were collected and GHG fluxes were measured during rainy and dry seasons at 5 sites along a gradient of development and nitrogen loading in the San Juan Bay Estuary. At each site, paired GHG flux measurements were performed for mangrove wetland soil and estuarine water using static and floating chambers. Our results suggest a positive relationship between urban development and CH4 and N2O emissions, and demonstrate that in this system, estuarine waters are a major methane source. In addition to providing characterization of GHG fluxes in an urban subtropical estuary, these data provide a baseline against which future states of the estuary (after planned hydrological restoration has been implemented) may be compared. In Puer

  17. Central San Juan caldera cluster: Regional volcanic framework

    USGS Publications Warehouse

    Lipman, Peter W.

    2000-01-01

    Eruption of at least 8800 km3 of dacitic-rhyolitic magma as 9 major ash-slow sheets (individually 150-5000 km3) was accompanied by recurrent caldera subsidence between 28.3 and about 26.5 Ma in the central San Juan Mountains, Colorado. Voluminous andesitic-decitic lavas and breccias were erupted from central volcanoes prior to the ash-flow eruptions, and similar lava eruptions continued within and adjacent to the calderas during the period of explosive volcanism, making the central San Juan caldera cluster an exceptional site for study of caldera-related volcanic processes. Exposed calderas vary in size from 10 to 75 km in maximum diameter, the largest calderas being associated with the most voluminous eruptions. After collapse of the giant La Garita caldera during eruption if the Fish Canyon Tuff at 17.6 Ma, seven additional explosive eruptions and calderas formed inside the La Garita depression within about 1 m.y. Because of the nested geometry, maximum loci of recurrently overlapping collapse events are inferred to have subsided as much as 10-17 km, far deeper than the roof of the composite subvolcanic batholith defined by gravity data, which represents solidified caldera-related magma bodies. Erosional dissection to depths of as much as 1.5 km, although insufficient to reach the subvolcanic batholith, has exposed diverse features of intracaldera ash-flow tuff and interleaved caldera-collapse landslide deposits that accumulated to multikilometer thickness within concurrently subsiding caldera structures. The calderas display a variety of postcollapse resurgent uplift structures, and caldera-forming events produced complex fault geometries that localized late mineralization, including the epithermal base- and precious-metal veins of the well-known Creede mining district. Most of the central San Juan calderas have been deeply eroded, and their identification is dependent on detailed geologic mapping. In contrast, the primary volcanic morphology of the

  18. Dr. Wernher Von Braun

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Shown viewing the Apollo telescope mockup are, from left to right, Charles Donlan, deputy associate administrator for manned space flight; Dr. Wernher Von Braun, Marshall Space Flight Center director; William Horton, astrionics lab; Dr. Thomas Paine, NASA deputy administrator; Warner Kuers, director of the ME lab.

  19. Las Cabezas de San Juan, Nature Reserve (El Faro).

    Treesearch

    P. L. Weaver; J. L. Ram¡rez; J. L. Coll

    1999-01-01

    The 178-hectarea(ha) northeastern tip of Puerto Rico, Which is known locally as "Las Cabezas de San Juan Nature Reserve", is managed by the Puerto Rican Conservation Trust to protect the area's scenic beauty and to provide enviromental education and research opportunities to the island's resident and visitors

  20. 33 CFR 334.1180 - Strait of Juan de Fuca, Wash.; air-to-surface weapon range, restricted area.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 3 2012-07-01 2012-07-01 false Strait of Juan de Fuca, Wash.; air-to-surface weapon range, restricted area. 334.1180 Section 334.1180 Navigation and Navigable... REGULATIONS § 334.1180 Strait of Juan de Fuca, Wash.; air-to-surface weapon range, restricted area. (a) The...

  1. 33 CFR 334.1180 - Strait of Juan de Fuca, Wash.; air-to-surface weapon range, restricted area.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 3 2014-07-01 2014-07-01 false Strait of Juan de Fuca, Wash.; air-to-surface weapon range, restricted area. 334.1180 Section 334.1180 Navigation and Navigable... REGULATIONS § 334.1180 Strait of Juan de Fuca, Wash.; air-to-surface weapon range, restricted area. (a) The...

  2. 33 CFR 334.1180 - Strait of Juan de Fuca, Wash.; air-to-surface weapon range, restricted area.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 3 2013-07-01 2013-07-01 false Strait of Juan de Fuca, Wash.; air-to-surface weapon range, restricted area. 334.1180 Section 334.1180 Navigation and Navigable... REGULATIONS § 334.1180 Strait of Juan de Fuca, Wash.; air-to-surface weapon range, restricted area. (a) The...

  3. 3 CFR 8947 - Proclamation 8947 of March 25, 2013. Establishment of the San Juan Islands National Monument

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... archipelago of over 450 islands, rocks, and pinnacles known as the San Juan Islands. These islands form an... the San Juan Islands have uncovered a unique array of fossils and other evidence of long-vanished..., within the boundaries described on the accompanying map, which is attached to and forms a part of this...

  4. 33 CFR 334.1180 - Strait of Juan de Fuca, Wash.; air-to-surface weapon range, restricted area.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 3 2011-07-01 2011-07-01 false Strait of Juan de Fuca, Wash.; air-to-surface weapon range, restricted area. 334.1180 Section 334.1180 Navigation and Navigable... REGULATIONS § 334.1180 Strait of Juan de Fuca, Wash.; air-to-surface weapon range, restricted area. (a) The...

  5. 33 CFR 334.1180 - Strait of Juan de Fuca, Wash.; air-to-surface weapon range, restricted area.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Strait of Juan de Fuca, Wash.; air-to-surface weapon range, restricted area. 334.1180 Section 334.1180 Navigation and Navigable... REGULATIONS § 334.1180 Strait of Juan de Fuca, Wash.; air-to-surface weapon range, restricted area. (a) The...

  6. Segmented Subduction Across the Juan De Fuca Plate: Challenges in Imaging with an Amphibious Array

    NASA Astrophysics Data System (ADS)

    Hawley, W. B.; Allen, R. M.

    2014-12-01

    The Cascadia Initiative (CI) is an amphibious array spanning the Juan de Fuca plate from formation at the ridge to the destruction of the slab in the mantle beneath western North America. This ambitions project has occupied over 300 onshore and offshore sites, providing an unprecedented opportunity to understand the dynamics of oceanic plates. The CI project is now in its fourth and final year of deployment. Here we present constraints on the structure of the Juan de Fuca plate and its interaction with western North America. We identify segmentation along the Cascadia subduction zone that can be traced back onto the Juan de Fuca plate prior to subduction. These results give insight into the life cycle of oceanic plates, from their creation at a mid-ocean ridge to their subduction and subsequent recycling into the mantle.

  7. Dr. Robert Goddard

    NASA Image and Video Library

    2010-01-04

    Dr. Robert Goddard and colleagues at Roswell, New Mexico. Successful test of May 19, 1937. Dr. Robert Goddard is holding the cap and pilot parachute, parts of the successful operation. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Join us on Facebook

  8. Dr. Gilruth and Dr. Kraft - Mission Control Center (MCC) - Apollo V Launch - MSC

    NASA Image and Video Library

    1968-01-22

    S68-18733 (22 Jan. 1968) --- Dr. Robert R. Gilruth (right), MSC Director, sits with Dr. Christopher C. Kraft Jr., MSC director of flight operations, at his flight operations director console in the Mission Control Center, Building 30, during the Apollo 5 (LM-1/Saturn 204) unmanned space mission.

  9. Dr. Robert Goddard

    NASA Image and Video Library

    2010-01-04

    Dr. Robert Hutchings Goddard (1882-1945). Dr. Goddard has been recognized as the father of American rocketry and as one of the pioneers in the theoretical exploration of space. Robert Hutchings Goddard, born in Worcester, Massachusetts, on October 5, 1882, was theoretical scientist as well as a practical engineer. His dream was the conquest of the upper atmosphere and ultimately space through the use of rocket propulsion. Dr. Goddard, died in 1945, but was probably as responsible for the dawning of the Space Age as the Wrights were for the beginning of the Air Age. Yet his work attracted little serious attention during his lifetime. However, when the United States began to prepare for the conquest of space in the 1950's, American rocket scientists began to recognize the debt owed to the New England professor. They discovered that it was virtually impossible to construct a rocket or launch a satellite without acknowledging the work of Dr. Goddard. More than 200 patents, many of which were issued after his death, covered this great legacy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Join us on Facebook

  10. Hazard evaluation of inorganics, singly and in mixtures, to Flannelmouth Sucker Catostomus latipinnis in the San Juan River, New Mexico

    USGS Publications Warehouse

    Hamilton, S.J.; Buhl, K.J.

    1997-01-01

    Larval flannelmouth sucker (Catostomus latipinnis) were exposed to arsenate, boron, copper, molybdenum, selenate, selenite, uranium, vanadium, and zinc singly, and to five mixtures of five to nine inorganics. The exposures were conducted in reconstituted water representative of the San Juan River near Shiprock, New Mexico. The mixtures simulated environmental ratios reported for sites along the San Juan River (San Juan River backwater, Fruitland marsh, Hogback East Drain, Mancos River, and McElmo Creek). The rank order of the individual inorganics, from most to least toxic, was: copper > zinc > vanadium > selenite > selenate > arsenate > uranium > boron > molybdenum. All five mixtures exhibited additive toxicity to flannelmouth sucker. In a limited number of tests, 44-day-old and 13-day-old larvae exhibited no difference in sensitivity to three mixtures. Copper was the major toxic component in four mixtures (San Juan backwater, Hogback East Drain, Mancos River, and McElmo Creek), whereas zinc was the major toxic component in the Fruitland marsh mixture, which did not contain copper. The Hogback East Drain was the most toxic mixture tested. Comparison of 96-h LC50values with reported environmental water concentrations from the San Juan River revealed low hazard ratios for arsenic, boron, molybdenum, selenate, selenite, uranium, and vanadium, moderate hazard ratios for zinc and the Fruitland marsh mixture, and high hazard ratios for copper at three sites and four environmental mixtures representing a San Juan backwater, Hogback East Drain, Mancos River, and McElmo Creek. The high hazard ratios suggest that inorganic contaminants could adversely affect larval flannelmouth sucker in the San Juan River at four sites receiving elevated inorganics.

  11. 77 FR 32116 - Findings of Research Misconduct

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-31

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Office of the Secretary Findings of Research Misconduct... Research Integrity (ORI) has taken final action in the following case: Juan Ma, Ph.D., Brigham and Women's... gathered by the Office of Research Integrity (ORI) during its oversight review, ORI found that Dr. Juan Ma...

  12. 78 FR 34128 - Notice of Inventory Completion: U.S. Department of Agriculture, U.S. Forest Service, San Juan...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-06

    ... DEPARTMENT OF THE INTERIOR National Park Service [NPS-WASO-NAGPRA-13012; PPWOCRADN0-PCU00RP14.R50000] Notice of Inventory Completion: U.S. Department of Agriculture, U.S. Forest Service, San Juan.... Department of Agriculture (USDA), Forest Service, San Juan National Forest has completed an inventory of...

  13. 75 FR 62112 - Intent To Prepare an Environmental Impact Statement (EIS) for the San Juan Creek and Tributaries...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-07

    ... Environmental Impact Statement (EIS) for the San Juan Creek and Tributaries Flood Risk Management Study, Orange... evaluate flood risk management alternative measures along the lower portions of San Juan, Trabuco, and Oso... Trabuco Creek have been channelized for flood risk management and erosion control within the City of San...

  14. Dr. Robert Goddard

    NASA Image and Video Library

    2010-01-04

    Dr. Robert Goddard on the campus of Clark University, Worcester, Mass. mounting a srocket chamber for the 1915-1916 experiments. Dr. Goddard earned his doctorate at Clark and also taught physics there. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Join us on Facebook

  15. Enrico Fermi Awards Ceremony for Dr. Allen J. Bard and Dr. Andrew Sessler, February 2014 (Presentations, including remarks by Energy Secretary, Dr. Ernest Moniz)

    ScienceCinema

    Moniz, Ernest; Dehmer, Patricia

    2018-05-04

    The Fermi Award is a Presidential award and is one of the oldest and most prestigious science and technology honors bestowed by the U.S. Government. On February 3, 2014 it was conferred upon two exceptional scientists. The first to be recognized is Dr. Allen J. Bard, 'for international leadership in electrochemical science and technology, for advances in photoelectrochemistry and photocatalytic materials, processes, and devices, and for discovery and development of electrochemical methods including electrogenerated chemiluminescence and scanning electrochemical microscopy.' The other honoree is Dr. Andrew Sessler, 'for advancing accelerators as powerful tools of scientific discovery, for visionary direction of the research enterprise focused on challenges in energy and the environment, and for championing outreach and freedom of scientific inquiry worldwide.' Dr. Patricia Dehmer opened the ceremony, and Dr. Ernest Moniz presented the awards.

  16. Dr. Wernher Von Braun Memorial Dinner

    NASA Image and Video Library

    2017-10-26

    The annual Dr. Wernher Von Braun Memorial Dinner was held at the U.S. Space and Rocket Center's Davidson Center on October 26, 2017 with Keynote speaker General John Hyten, Commander of U.S. Strategic Command. Emcee was Mark Larson of Mark Larson Media Services, Inc. Dr. Wernher Von Braun Memorial Scholarships were presented to 8 college students by the National Space Club. Educator of the Year was awarded to Tammy Thorpe; Community Service award was presented to Huntsville, Al. Mayor Tommy Battle. The Communications Award was presented to retired astronaut Dr. Mike Massimino. The Distinguished Science Award was presented to Dr. Martin Weisskopf. The Astronautics Engineer Award was presented to Douglas R. Cooke. The Dr. Wernher Von Braun Space Flight Trophy was presented to Robert Lightfoot.

  17. ["Is it an animal inside? "Melanie Klein's unpublished Don Juan Paper (1939)].

    PubMed

    Frank, Claudia

    2008-01-01

    Klein had been asked to contribute an article to the birthday number of the International Journal for Jones. The author outlines how she hurriedly wrote a text about Don Juan which, however, was rejected by the editor. Essential parts of it are presented in German translation. The manuscript is discussed in the context of Klein's published work as well as of the relevant contemporary literature. In Klein's view, Don Juan's genitality is determined by oral impulses and fears. By his manic acting out he attempts to ward off a depressive break-down. The paper ends with some reflections about why Klein--ontrary to her intention--failed to revise her manuscript for later publication.

  18. Type 1 diabetes risk for HLA-DR3 haplotypes depends on genotypic context: Association of DPB1 and HLA class I loci among DR3 and DR4 matched Italian patients and controls

    PubMed Central

    Noble, Janelle A.; Martin, Adelle; Valdes, Ana M.; Lane, Julie A.; Galgani, Andrea; Petrone, Antonio; Lorini, Renata; Pozzilli, Paolo; Buzzetti, Raffaella; Erlich, Henry A.

    2008-01-01

    Patients with high-risk HLA-DR-DQ genotypes for type 1 diabetes (T1D) were compared to HLA-matched controls to evaluate T1D risk for other HLA loci, including HLA-A, -B, -Cw, and DPB1. Patients (n=133) with high-risk genotypes (DR3/DR3, DR3/DR4, DR4/DR4) were selected from the Lazio (Rome) region of Italy. Screening of more than 9000 subjects from the Lazio region and northern Italy yielded 162 controls with high- T1D-risk haplotypes. Although the overall distributions were not significantly different, allele frequency differences were discovered between the controls from Lazio and those from Northern Italy for some alleles previously shown to affect T1D risk, such as A*3002, DPB1*0301, and DPB1*0402. Therefore, Lazio patient data were compared both to the Lazio subset of controls (n=53) and to the entire group of controls for association analyses. Significant allele frequency differences between patients and DR-DQ-matched controls were found for specific alleles at all loci. Data for the DR3/DR3 subset of patients and controls showed an increase of Cw*0702 in patients. Reduced patient, compared to control, frequencies were seen for several alleles, including A*0101, B*0801, and Cw*0701, all found on the highly-conserved, extended DR3 haplotype known as 8.1 in DR3/DR3, but not DR3/DR4, subgroup. DPB1*0101, often found on 8.1 haplotypes, was also less frequent in DR3/DR3 patients than controls. Analysis of family-based data from the HBDI repository was consistent with the observed results from the Italian subjects, suggesting the presence of a T1D-protective locus at or near A*0101 and a second T1D-protective locus at or near DPB1*0101. These data suggest that T1D risk conferred by the 8.1 haplotype is genotype dependent. PMID:18486765

  19. Local Control and Self-Determination: The San Juan Case.

    ERIC Educational Resources Information Center

    Garman, Keats; Jack, Donald

    Rapidly increasing Navajo enrollment in San Juan County, Utah, public schools in the 1960's forced the rural school district to improve educational services to a sizable Navajo population while attempting to preserve local control in the face of changing Indian self-determination policy. The district implemented a Curriculum Development Center, a…

  20. Geochronology and geology of late Oligocene through Miocene volcanism and mineralization in the western San Juan Mountains, Colorado

    USGS Publications Warehouse

    Bove, Dana J.; Hon, Ken; Budding, Karin E.; Slack, John F.; Snee, Lawrence W.; Yeoman, Ross A.

    2001-01-01

    This paper presents 25 new 40Ar/39Ar dates from the main calc-alkaline ash-flow sheets and related younger plutons of the western San Juan volcanic field, the ash-flow sheets of the Lake City caldera cycle, and veins and other altered rocks in the Lake City region. The goal of the study was to produce similar quality 40Ar/39Ar ages to those currently published for the eastern and central San Juan Mountains. These new data provide a much more precise chronological framework for interpreting durations of events and their relationship to mineralization than do previously published conventional K-Ar dates for the western San Juan Mountains.

  1. Assessing Climate Variability Effects on Dengue Incidence in San Juan, Puerto Rico

    PubMed Central

    Méndez-Lázaro, Pablo; Muller-Karger, Frank E.; Otis, Daniel; McCarthy, Matthew J.; Peña-Orellana, Marisol

    2014-01-01

    We test the hypothesis that climate and environmental conditions are becoming favorable for dengue transmission in San Juan, Puerto Rico. Sea Level Pressure (SLP), Mean Sea Level (MSL), Wind, Sea Surface Temperature (SST), Air Surface Temperature (AST), Rainfall, and confirmed dengue cases were analyzed. We evaluated the dengue incidence and environmental data with Principal Component Analysis, Pearson correlation coefficient, Mann-Kendall trend test and logistic regressions. Results indicated that dry days are increasing and wet days are decreasing. MSL is increasing, posing higher risk of dengue as the perimeter of the San Juan Bay estuary expands and shorelines move inland. Warming is evident with both SST and AST. Maximum and minimum air surface temperature extremes have increased. Between 1992 and 2011, dengue transmission increased by a factor of 3.4 (95% CI: 1.9–6.1) for each 1 °C increase in SST. For the period 2007–2011 alone, dengue incidence reached a factor of 5.2 (95% CI: 1.9–13.9) for each 1 °C increase in SST. Teenagers are consistently the age group that suffers the most infections in San Juan. Results help understand possible impacts of different climate change scenarios in planning for social adaptation and public health interventions. PMID:25216253

  2. San Juan Bay Estuary watershed urban forest inventory

    Treesearch

    Thomas J. Brandeis; Francisco J. Escobedo; Christina L. Staudhammer; David J. Nowak; Wayne C. Zipperer

    2014-01-01

    We present information on the urban forests and land uses within the watershed of Puerto Rico’s 21 658-ha San Juan Bay Estuary based on urban forest inventories undertaken in 2001 and 2011. We found 2548 ha of mangrove and subtropical moist secondary forests covering 11.8 percent of the total watershed area in 2011. Red, black, and white mangroves (Rhizophora...

  3. Bedrock aquifers of eastern San Juan County, Utah

    USGS Publications Warehouse

    Avery, Charles

    1986-01-01

    This study is one of a series of studies appraising the waterbearing properties of the Navajo Sandstone and associated formations in southern Utah.  The stu<¥ area is al:x>dy area is about 4,600 square miles, extending from the Utah-Arizona State line northward to the San Juan-Grand County line and westward from the Utah-Colorado State line to the longitude of about 109°50'.Some of the water-yielding formations are grouped into aquifer systems. The C aquifer is comprised of the DeChelly Sandstone Member of the Cutler Formation.  The P aquifer is comprised of the Cedar Mesa Member of the Cutler Formation and the undifferentiated Cutler Formation. The N aquifer is comprised of the sedimentary section that includes the Wingate Sandstone, Kayenta Formation, Navajo Sandstone, Carmel Formation, and Entrada sandstone.  The M aquifer is comprised of the Bluff Sandstone Member and other sandstone units of the Morrison Formation.  The D aquifer is comprised of the Burro Canyon Formation and Dakota Sandstone.  Discharge from the ground-water reservoir to the San Juan River between gaging stations at Four Corners and Mexican Hat is about 66 cubic feet per second.The N aquifer is the main aquifer in the study area. Recharge by infiltration of precipitation is estimated to be 25,000 acre-feet per year.  A major ground-water divide exists under the broad area east of Monticello.  The thickness of the N aquifer, where the sedimentary section is fully preserved and saturated, generally is 750 to 1,250 feet.   Hydraulic conductivity values obtained from aquifer tests range from 0.02 to 0.34 foot per day.  The total volume of water in transient storage is about 11 million acre-feet. Well discharge somewhat exceeded 2,340 acre-feet during 1981.  Discharge to the San Juan River from the N aquifer is estimated to be 6.9 cubic feet per second. Water quality ranges from a calcium bicarbonate to sodium chloride type water

  4. El Atlas del Bosque Nacional El Yunque

    Treesearch

    Maya Quiñones; Isabel K. Parés-Ramos; William A. Gould; Grizelle Gonzalez; Kathleen McGinley; Pedro. Ríos

    2018-01-01

    Esta publicación es un esfuerzo colaborativo entre el Instituto Internacional de Dasonomía Tropical y el Bosque Nacional El Yunque para proveer mapas y análisis de información espacial actualizados sobre una importante reserva natural en Puerto Rico y el único bosque tropical dentro del Sistema de Bosques Nacionales de los Estados Unidos. El Atlas del Bosque Nacional...

  5. Enrico Fermi Awards Ceremony for Dr. Allen J. Bard and Dr. Andrew Sessler, February 2014 (Presentations, including remarks by Energy Secretary, Dr. Ernest Moniz)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Moniz, Ernest; Dehmer, Patricia

    The Fermi Award is a Presidential award and is one of the oldest and most prestigious science and technology honors bestowed by the U.S. Government. On February 3, 2014 it was conferred upon two exceptional scientists. The first to be recognized is Dr. Allen J. Bard, 'for international leadership in electrochemical science and technology, for advances in photoelectrochemistry and photocatalytic materials, processes, and devices, and for discovery and development of electrochemical methods including electrogenerated chemiluminescence and scanning electrochemical microscopy.' The other honoree is Dr. Andrew Sessler, 'for advancing accelerators as powerful tools of scientific discovery, for visionary direction of themore » research enterprise focused on challenges in energy and the environment, and for championing outreach and freedom of scientific inquiry worldwide.' Dr. Patricia Dehmer opened the ceremony, and Dr. Ernest Moniz presented the awards.« less

  6. The Importance of a "Good Fit"

    ERIC Educational Resources Information Center

    Kelleher, Paul

    2006-01-01

    The Sunnyside Independent School District Board of Education selected Dr. Juan Martinez (pseudonym) as its new superintendent of schools by an unusually cohesive 7-0 vote in 2002. In describing the superintendent search, the local paper characterized the board as highly politicized and often divisive. So the board's unanimity in appointing Juan to…

  7. Putting Educational Attainment First: An Interview with Juan Sepulveda

    ERIC Educational Resources Information Center

    Carreon, Joe

    2011-01-01

    This article presents an interview with Juan Sepulveda. Sepulveda was appointed by U.S. Secretary of Education Arne Duncan to the position of Executive Director of the White House Initiative on Educational Excellence for Hispanics on May 19, 2009. In this capacity, Sepulveda is responsible for directing the efforts of the White House Initiative in…

  8. Multiwavelength observations of two B-star nurseries - DR 15 and DR 20

    NASA Technical Reports Server (NTRS)

    Odenwald, S. F.; Campbell, M. F.; Shivanandan, K.; Schwartz, P.; Fazio, G. G.; Moseley, H.

    1990-01-01

    New observations of DR 15 and 20 are reported as part of a study of compact H II regions in the Cyg X region. The radio and FIR data for these objects, when combined with (C-12)O maps, IRAS imagery, and optical photographs, provide new insights into the structure of this complex region and the nature of the star-formation process there. The observations show that DR 15 may consist of one or two B0 ZAMS stars whose H I regions have formed a low-density cavity within a molecular cloud. DR 20 appears to be a young OB cluster. The cluster is dominated by an O5.5 ZAMS star and also contains an approximately 3500-yr-old B0 star appearing as a compact H II region, along with weak FIR sources that may be B0-star candidates.

  9. 77 FR 47358 - San Juan National Forest Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-08

    ... Advisory Council (RAC) will meet in Durango, Colorado. The committee is authorized under the Secure Rural..., 15 Burnett Court, Durango, Colorado in the Sonoran Meeting Rooms. Committee members will be allowed.../ or the Public Reading Room, San Juan Public Lands Center Building, 15 Burnett Court, Durango...

  10. San Juan College Task Force on Innovation 1995 Report.

    ERIC Educational Resources Information Center

    Moore, Nelle

    In fall 1994, San Juan College, in New Mexico, established the Task Force on Innovation to examine changes in the paradigm of education and how those changes might affect the college. The Task Force determined that the primary driver of change in education was technology, and specifically the increasing number of means and ease of access to…

  11. Mineralogy from Cores in Prospect Gulch, San Juan County, Colorado

    USGS Publications Warehouse

    Bove, Dana J.; Johnson, Raymond H.; Yager, Douglas B.

    2007-01-01

    In the late nineteenth century, San Juan County, Colorado, was the center of a metal mining boom in the San Juan Mountains. Although most mining activity ceased by the 1990s, the effects of historical mining continue to contribute metals to ground water and surface water. Previous research by the U.S. Geological Survey identified ground-water discharge as a significant pathway for the loading of metals to surface water from both acid-mine drainage and acid-rock drainage. In an effort to understand the ground-water flow system in the upper Animas River watershed, Prospect Gulch was selected for further study because of the amount of previous data provided in and around that particular watershed. In support of this ground-water research effort, data was collected from drill core, which included: (1) detailed descriptions of the subsurface geology and hydrothermal alteration patterns, (2) depth of sulfide oxidation, and (3) quantitative mineralogy.

  12. Dr Pugh: a poisoner?

    PubMed

    Paull, J D; Morris, G M

    2012-07-01

    On 16 February 1845 the Reverend W. H. Browne, rector of St John's Church in Launceston, Van Diemen's Land, wrote in his journal, "My dear Wife died very suddenly almost immediately after and in consequence of taking a preparation of Hyd. Cyan. Acid prepared & supplied by Dr Pugh". This journal entry raises a number of questions. Was Dr Pugh treating a condition which he thought merited that treatment or was it a ghastly mistake? Was Caroline Browne suffering from pulmonary tuberculosis? Was hydrocyanic acid an accepted treatment at that time? Did Mrs Browne take the wrong dose? Was an incorrect concentration of the drug prepared by Dr Pugh? Did he use the wrong pharmacopoeia in preparing the hydrocyanic acid? Why was there no inquest? Only some of these questions can be answered.

  13. Geology, thermal maturation, and source rock geochemistry in a volcanic covered basin: San Juan sag, south-central Colorado

    USGS Publications Warehouse

    Gries, R.R.; Clayton, J.L.; Leonard, C.

    1997-01-01

    The San Juan sag, concealed by the vast San Juan volcanic field of south-central Colorado, has only recently benefited from oil and gas wildcat drilling and evaluations. Sound geochemical analyses and maturation modeling are essential elements for successful exploration and development. Oil has been produced in minor quantities from an Oligocene sill in the Mancos Shale within the sag, and major oil and gas production occurs from stratigraphically equivalent rocks in the San Juan basin to the south-west and in the Denver basin to the northeast. The objectives of this study were to identify potential source rocks, assess thermal maturity, and determine hydrocarbon-source bed relationships. Source rocks are present in the San Juan sag in the upper and lower Mancos Shale (including the Niobrara Member), which consists of about 666 m (2184 ft) of marine shale with from 0.5 to 3.1 wt. % organic carbon. Pyrolysis yields (S1 + S2 = 2000-6000 ppm) and solvent extraction yields (1000-4000 ppm) indicate that some intervals within the Mancos Shale are good potential source rocks for oil, containing type II organic matter, according to Rock-Eval pyrolysis assay. Oils produced from the San Juan sag and adjacent part of the San Juan basin are geochemically similar to rock extracts obtained from these potential source rock intervals. Based on reconstruction of the geologic history of the basin integrated with models of organic maturation, we conclude that most of the source rock maturation occurred in the Oligocene and Miocene. Little to no maturation took place during Laramide subsidence of the basin, when the Animas and Blanco Basin formations were deposited. The timing of maturation is unlike that of most Laramide basins in the Rocky Mountain region, where maturation occurred as a result of Paleocene and Eocene basin fill. The present geothermal gradient in the San Juan sag is slightly higher (average 3.5??C/100 m; 1.9??F/100 ft) than the regional average for southern Rocky

  14. 33 CFR 161.55 - Vessel Traffic Service Puget Sound and the Cooperative Vessel Traffic Service for the Juan de...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Reporting Points § 161.55 Vessel Traffic Service Puget Sound and the Cooperative Vessel Traffic Service for the Juan de Fuca Region. The Vessel Traffic Service Puget Sound area consists of the navigable waters... Boundary Range C Rear Light). This area includes: Puget Sound, Hood Canal, Possession Sound, the San Juan...

  15. Pathogenesis of Human Diffusely Adhering Escherichia coli Expressing Afa/Dr Adhesins (Afa/Dr DAEC): Current Insights and Future Challenges

    PubMed Central

    2014-01-01

    SUMMARY The pathogenicity and clinical pertinence of diffusely adhering Escherichia coli expressing the Afa/Dr adhesins (Afa/Dr DAEC) in urinary tract infections (UTIs) and pregnancy complications are well established. In contrast, the implication of intestinal Afa/Dr DAEC in diarrhea is still under debate. These strains are age dependently involved in diarrhea in children, are apparently not involved in diarrhea in adults, and can also be asymptomatic intestinal microbiota strains in children and adult. This comprehensive review analyzes the epidemiology and diagnosis and highlights recent progress which has improved the understanding of Afa/Dr DAEC pathogenesis. Here, I summarize the roles of Afa/Dr DAEC virulence factors, including Afa/Dr adhesins, flagella, Sat toxin, and pks island products, in the development of specific mechanisms of pathogenicity. In intestinal epithelial polarized cells, the Afa/Dr adhesins trigger cell membrane receptor clustering and activation of the linked cell signaling pathways, promote structural and functional cell lesions and injuries in intestinal barrier, induce proinflammatory responses, create angiogenesis, instigate epithelial-mesenchymal transition-like events, and lead to pks-dependent DNA damage. UTI-associated Afa/Dr DAEC strains, following adhesin-membrane receptor cell interactions and activation of associated lipid raft-dependent cell signaling pathways, internalize in a microtubule-dependent manner within urinary tract epithelial cells, develop a particular intracellular lifestyle, and trigger a toxin-dependent cell detachment. In response to Afa/Dr DAEC infection, the host epithelial cells generate antibacterial defense responses. Finally, I discuss a hypothetical role of intestinal Afa/Dr DAEC strains that can act as “silent pathogens” with the capacity to emerge as “pathobionts” for the development of inflammatory bowel disease and intestinal carcinogenesis. PMID:25278576

  16. CancerDR: cancer drug resistance database.

    PubMed

    Kumar, Rahul; Chaudhary, Kumardeep; Gupta, Sudheer; Singh, Harinder; Kumar, Shailesh; Gautam, Ankur; Kapoor, Pallavi; Raghava, Gajendra P S

    2013-01-01

    Cancer therapies are limited by the development of drug resistance, and mutations in drug targets is one of the main reasons for developing acquired resistance. The adequate knowledge of these mutations in drug targets would help to design effective personalized therapies. Keeping this in mind, we have developed a database "CancerDR", which provides information of 148 anti-cancer drugs, and their pharmacological profiling across 952 cancer cell lines. CancerDR provides comprehensive information about each drug target that includes; (i) sequence of natural variants, (ii) mutations, (iii) tertiary structure, and (iv) alignment profile of mutants/variants. A number of web-based tools have been integrated in CancerDR. This database will be very useful for identification of genetic alterations in genes encoding drug targets, and in turn the residues responsible for drug resistance. CancerDR allows user to identify promiscuous drug molecules that can kill wide range of cancer cells. CancerDR is freely accessible at http://crdd.osdd.net/raghava/cancerdr/

  17. Geochemical and Isotopic Estimates of Eolian Dust in Soils of the San Juan Mountains, USA.

    NASA Astrophysics Data System (ADS)

    Lawrence, C. R.; Neff, J. C.; Farmer, L.; Painter, T. H.; Landry, C.

    2007-12-01

    Eolian dust deposition in the San Juan Mountain Range in southern Colorado has increased 5-7 fold in the past two centuries. This dust deposition contributes an exogenous supply of biologically relevant elements such as Ca, K, Mg, and P to these alpine ecosystems in the form of fine textured mineral particulates. The deposition of eolian dust may be an underestimated factor of soil formation and soil chemistry in these alpine settings. The importance of eolian dust relative to the weathering of local bedrock likely varies across bedrock types. The San Juan Range is geologically diverse with distinct regions of Meso-proterozic crystalline granites in the Weminuche Wilderness, Mesozoic sedimentary layers near Molas Pass in the San Juan National Forest, and Tertiary volcanic geology found on Red Mountain Pass in the Uncompahgre National Forest. Principle component analysis of element chemistry shows that bedrock and soils from these sites cluster by geology. In addition, these groups are chemically distinct from eolian dust collected from snow in the San Juan Range. Several elements seem to drive the difference of dust from soils and bedrock including Ca, Sr, Cu and Cd. The purpose of this research was to estimate the relative contribution of eolian dust to alpine soil element pools in the San Juan Mountains across a range of local geologic parent material. A calculation of element mass- balance shows that Cu and Cd are enriched in the surface soils of both volcanic and sedimentary soils relative to concentrations in local bedrock. However, Ca is enriched only in volcanic soils. These observations support the notion that eolian dust contributes to soil formation and that the relative contribution of dust across the landscape varies with geology. In addition to element mass-balance estimates we utilize Sr and Nd isotope measurements of soil, bedrock, and dust to further constrain the importance of eolian dust to these alpine soils.

  18. Papers Selected for Presentation at the International Symposium on Remote Sensing of Environment (16th) Held at Buenos Aires, Argentina on 2-9 June 1982. Volume 2.

    DTIC Science & Technology

    1982-06-01

    ARGENTINA Oscar Dominguez and Stella Carballo .............. 355 STUDIES ON SOME URBAN PROBLEMS USING AIRBORNE REMOTE SENSORS IN SANTIAGO, CHILE ...SAN JUAN ARGENTINA) (1) Silvia Lendaro de Gianni (2,3) Enrique Uliarte (I) Centro Regional de Agua Subterrgnea (2) Universidad Nacional de San Juan act...Hidrogeol6gico para refuerzo do la provisi6n de agua " a Puerto Deseado. In4dito. - Pezzuchi, Hugo Daniel (1978) "studio Geol6gico de la zona de Lstancia Dos

  19. Pathogenesis of human diffusely adhering Escherichia coli expressing Afa/Dr adhesins (Afa/Dr DAEC): current insights and future challenges.

    PubMed

    Servin, Alain L

    2014-10-01

    The pathogenicity and clinical pertinence of diffusely adhering Escherichia coli expressing the Afa/Dr adhesins (Afa/Dr DAEC) in urinary tract infections (UTIs) and pregnancy complications are well established. In contrast, the implication of intestinal Afa/Dr DAEC in diarrhea is still under debate. These strains are age dependently involved in diarrhea in children, are apparently not involved in diarrhea in adults, and can also be asymptomatic intestinal microbiota strains in children and adult. This comprehensive review analyzes the epidemiology and diagnosis and highlights recent progress which has improved the understanding of Afa/Dr DAEC pathogenesis. Here, I summarize the roles of Afa/Dr DAEC virulence factors, including Afa/Dr adhesins, flagella, Sat toxin, and pks island products, in the development of specific mechanisms of pathogenicity. In intestinal epithelial polarized cells, the Afa/Dr adhesins trigger cell membrane receptor clustering and activation of the linked cell signaling pathways, promote structural and functional cell lesions and injuries in intestinal barrier, induce proinflammatory responses, create angiogenesis, instigate epithelial-mesenchymal transition-like events, and lead to pks-dependent DNA damage. UTI-associated Afa/Dr DAEC strains, following adhesin-membrane receptor cell interactions and activation of associated lipid raft-dependent cell signaling pathways, internalize in a microtubule-dependent manner within urinary tract epithelial cells, develop a particular intracellular lifestyle, and trigger a toxin-dependent cell detachment. In response to Afa/Dr DAEC infection, the host epithelial cells generate antibacterial defense responses. Finally, I discuss a hypothetical role of intestinal Afa/Dr DAEC strains that can act as "silent pathogens" with the capacity to emerge as "pathobionts" for the development of inflammatory bowel disease and intestinal carcinogenesis. Copyright © 2014, American Society for Microbiology. All Rights

  20. Dr. von Braun Briefing Walt Disney

    NASA Technical Reports Server (NTRS)

    1965-01-01

    Dr. von Braun began his association with Walt Disney in the 1950s when the rocket scientist appeared in three Disney television productions related to the exploration of space. Years later, Dr. von Braun invited Disney and his associates to tour the Marshall Space Flight Center (MSFC) in Huntsville, Alabama. This photograph is dated April 13, 1965. From left are R.J. Schwinghamer from the MSFC, Disney, B.J. Bernight, and Dr. von Braun.

  1. Ladrillo and Tales of Juan Bobo: Puerto Rican Folk Tales.

    ERIC Educational Resources Information Center

    Matos, Reinaldo; Matos, Ana

    These two illustrated elementary readers contain the Spanish and English versions of the Puerto Rican folk tales, "Ladrillo" and "Cuentos de Juan Bobo." They are part of a series of reading materials for elementary-level migrant children. These materials are intended to help the child relate to his culture, develop interest in…

  2. Dr. Wernher von Braun

    NASA Technical Reports Server (NTRS)

    2004-01-01

    Dr. von Braun is looking out from a 10th floor window of building 4200 at the Marshall Space Flight Center (MSFC). He was the first Center Director and served as the Director from July 1960 through February 1970. Following World War II, Dr. von Braun and his German colleagues arrived in the United States under the Project Paperclip (American acquisition of German rocket experts) to continue their rocket development work. In 1950, von Braun and his German Rocket Team (also called the Peenemuende Team) were transferred from Ft. Bliss, Texas to Huntsville, Alabama to work for the Army's rocket program at Redstone Arsenal and later, NASA's Marshall Space Flight Center (MSFC). Under Dr. von Braun's leadership, MSFC developed the Saturn V launch vehicle, which placed the first men, two American astronauts, on the Moon. Wernher von Braun's life was dedicated to expanding man's knowledge through the exploration of space.

  3. 76 FR 12692 - San Juan National Forest Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-08

    ... Advisory Council (RAC) will meet in Durango, Colorado. The committee is meeting as authorized under the...: The meeting will be held at the San Juan Public Lands Center, 15 Burnett Court, Durango, Colorado in... Burnett Court, Durango, CO 81301. Comments may also be sent via e-mail to [email protected] or via facsimile...

  4. 76 FR 40876 - San Juan National Forest Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-12

    ... Advisory Council (RAC) will meet in Durango, Colorado. The committee is meeting as authorized under the.... ADDRESSES: The meeting will be held at the San Juan Public Lands Center, 15 Burnett Court, Durango, Colorado..., 15 Burnett Court, Durango, CO 81301. Comments may also be sent via e-mail to [email protected] or via...

  5. 75 FR 48306 - San Juan National Forest Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-10

    ... Advisory Council (RAC) will meet in Durango, Colorado. The committee is meeting as authorized under the...: The meeting will be held at the San Juan Public Lands Center, 15 Burnett Court, Durango, Colorado in... Burnett Court, Durango, CO 81301. Comments may also be sent via e-mail to [email protected] or via facsimile...

  6. Geologic map of the Cochetopa Park and North Pass Calderas, northeastern San Juan Mountains, Colorado

    USGS Publications Warehouse

    Lipman, Peter W.

    2012-01-01

    The San Juan Mountains in southwestern Colorado have long been known as a site of exceptionally voluminous mid-Tertiary volcanism, including at least 22 major ignimbrite sheets (each 150-5,000 km3) and associated caldera structures active at 33-23 Ma. Recent volcanologic and petrologic studies in the San Juan region have focused mainly on several ignimbrite-caldera systems: the southeastern area (Platoro complex), western calderas (Uncompahgre-Silverton-Lake City), and the central cluster (La Garita-Creede calderas). Far less studied has been the northeastern San Juan region, which occupies a transition between earlier volcanism in central Colorado and large-volume younger ignimbrite-caldera foci farther south and west. The present map is based on new field coverage of volcanic rocks in seventeen 7.5' quadrangles in northeastern parts of the volcanic field, high-resolution age determinations for 120 new sites, and petrologic studies involving several hundred new chemical analyses. This mapping and the accompanying lab results (1) document volcanic evolution of the previously unrecognized North Pass caldera and the morphologically beautifully preserved but enigmatic Cochetopa basin, including unique features not previously described from ignimbrite calderas elsewhere; (2) provide evidence for a more rapid recurrence of large ignimbrite eruptions than previously known elsewhere; (3) quantify the regional time-space-volume progression from the earlier Sawatch magmatic trend southward into the San Juan region; and (4) permit more rigorous comparison between the broad mid-Tertiary magmatic belt in the western U.S. Cordillera and the type continental-margin arc volcanism in the central Andes.

  7. 76 FR 23191 - Traffic Separation Schemes: In the Strait of Juan de Fuca and Its Approaches; in Puget Sound and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-26

    ...-AA48 Traffic Separation Schemes: In the Strait of Juan de Fuca and Its Approaches; in Puget Sound and... rule codifying traffic separation schemes in the Strait of Juan de Fuca and its Approaches; in Puget... established these traffic separation schemes under authority of the Ports and Waterways Safety Act. DATES...

  8. 75 FR 70818 - Traffic Separation Schemes: In the Strait of Juan de Fuca and Its Approaches; in Puget Sound and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-19

    ...-AA48 Traffic Separation Schemes: In the Strait of Juan de Fuca and Its Approaches; in Puget Sound and..., the Coast Guard codifies traffic separation schemes in the Strait of Juan de Fuca and its approaches.... These traffic separation schemes (TSSs) were validated by a Port Access Route Study (PARS) conducted...

  9. Dr. Robert H. Goddard

    NASA Image and Video Library

    2010-01-04

    Dr. Robert Hutchings Goddard (1882-1945). Dr. Goddard has been recognized as the father of American rocketry and as one of the pioneers in the theoretical exploration of space. Robert Hutchings Goddard, born in Worcester, Massachusetts, on October 5, 1882, was theoretical scientist as well as a practical engineer. His dream was the conquest of the upper atmosphere and ultimately space through the use of rocket propulsion. Dr. Goddard, died in 1945, but was probably as responsible for the dawning of the Space Age as the Wrights were for the beginning of the Air Age. Yet his work attracted little serious attention during his lifetime. However, when the United States began to prepare for the conquest of space in the 1950's, American rocket scientists began to recognize the debt owed to the New England professor. They discovered that it was virtually impossible to construct a rocket or launch a satellite without acknowledging the work of Dr. Goddard. More than 200 patents, many of which were issued after his death, covered this great legacy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Join us on Facebook

  10. 33 CFR 167.1314 - In the Strait of Juan de Fuca: Eastern lanes.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY OFFSHORE TRAFFIC SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Pacific West Coast § 167.1314 In the Strait of Juan de...

  11. 33 CFR 167.1312 - In the Strait of Juan de Fuca: Southern lanes.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY OFFSHORE TRAFFIC SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Pacific West Coast § 167.1312 In the Strait of Juan de...

  12. 33 CFR 167.1311 - In the Strait of Juan de Fuca: Western lanes.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY OFFSHORE TRAFFIC SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Pacific West Coast § 167.1311 In the Strait of Juan de...

  13. 33 CFR 167.1314 - In the Strait of Juan de Fuca: Eastern lanes.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY OFFSHORE TRAFFIC SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Pacific West Coast § 167.1314 In the Strait of Juan de...

  14. 33 CFR 167.1313 - In the Strait of Juan de Fuca: Northern lanes.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY OFFSHORE TRAFFIC SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Pacific West Coast § 167.1313 In the Strait of Juan de...

  15. 33 CFR 167.1311 - In the Strait of Juan de Fuca: Western lanes.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY OFFSHORE TRAFFIC SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Pacific West Coast § 167.1311 In the Strait of Juan de...

  16. 33 CFR 167.1311 - In the Strait of Juan de Fuca: Western lanes.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY OFFSHORE TRAFFIC SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Pacific West Coast § 167.1311 In the Strait of Juan de...

  17. 33 CFR 167.1314 - In the Strait of Juan de Fuca: Eastern lanes.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY OFFSHORE TRAFFIC SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Pacific West Coast § 167.1314 In the Strait of Juan de...

  18. 33 CFR 167.1313 - In the Strait of Juan de Fuca: Northern lanes.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY OFFSHORE TRAFFIC SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Pacific West Coast § 167.1313 In the Strait of Juan de...

  19. 33 CFR 167.1314 - In the Strait of Juan de Fuca: Eastern lanes.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY OFFSHORE TRAFFIC SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Pacific West Coast § 167.1314 In the Strait of Juan de...

  20. 33 CFR 167.1312 - In the Strait of Juan de Fuca: Southern lanes.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY OFFSHORE TRAFFIC SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Pacific West Coast § 167.1312 In the Strait of Juan de...

  1. 33 CFR 167.1311 - In the Strait of Juan de Fuca: Western lanes.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY OFFSHORE TRAFFIC SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Pacific West Coast § 167.1311 In the Strait of Juan de...

  2. 33 CFR 167.1313 - In the Strait of Juan de Fuca: Northern lanes.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY OFFSHORE TRAFFIC SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Pacific West Coast § 167.1313 In the Strait of Juan de...

  3. 33 CFR 167.1312 - In the Strait of Juan de Fuca: Southern lanes.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY OFFSHORE TRAFFIC SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Pacific West Coast § 167.1312 In the Strait of Juan de...

  4. 33 CFR 167.1313 - In the Strait of Juan de Fuca: Northern lanes.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY OFFSHORE TRAFFIC SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Pacific West Coast § 167.1313 In the Strait of Juan de...

  5. 33 CFR 167.1312 - In the Strait of Juan de Fuca: Southern lanes.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY OFFSHORE TRAFFIC SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Pacific West Coast § 167.1312 In the Strait of Juan de...

  6. 33 CFR 334.1200 - Strait of Juan de Fuca, eastern end; off the westerly shore of Whidbey Island; naval restricted...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 3 2011-07-01 2011-07-01 false Strait of Juan de Fuca, eastern end; off the westerly shore of Whidbey Island; naval restricted areas. 334.1200 Section 334.1200... AND RESTRICTED AREA REGULATIONS § 334.1200 Strait of Juan de Fuca, eastern end; off the westerly shore...

  7. 33 CFR 334.1200 - Strait of Juan de Fuca, eastern end; off the westerly shore of Whidbey Island; naval restricted...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Strait of Juan de Fuca, eastern end; off the westerly shore of Whidbey Island; naval restricted areas. 334.1200 Section 334.1200... AND RESTRICTED AREA REGULATIONS § 334.1200 Strait of Juan de Fuca, eastern end; off the westerly shore...

  8. No spreading across the southern Juan de Fuca ridge axial cleft during 1994-1996

    USGS Publications Warehouse

    Chadwell, C.D.; Hildebrand, J.A.; Spiess, Fred N.; Morton, J.L.; Normark, W.R.; Reiss, C.A.

    1999-01-01

    Direct-path acoustic measurements between seafloor transponders observed no significant extension (-10 ?? 14 mm/yr) from August 1994 to September 1996 at the southern Juan de Fuca Ridge (44??40' N and 130??20' W). The acoustic path for the measurement is a 691-m baseline straddling the axial cleft, which bounds the Pacific and Juan de Fuca plates. Given an expected full-spreading rate of 56 mm/yr, these data suggest that extension across this plate boundary occurs episodically within the narrow (~1 km) region of the axial valley floor, and that active deformation is occurring between the axial cleft and the plate interior. A cleft-parallel 714-m baseline located 300 m to the west of the cleft on the Pacific plate monitored system performance and, as expected, observed no motion (+5??7 mm/yr) between the 1994 and 1996 surveys.Direct-path acoustic measurements between seafloor transponders observed no significant extension (-10 ?? 14 mm/yr) from August 1994 to September 1996 at the southern Juan de Fuca Ridge (44??40 minutes N and 130??20 minutes W). The acoustic path for the measurement is a 691-m baseline straddling the axial cleft, which bounds the Pacific and Juan de Fuca plates. Given an expected full-spreading rate of 56 mm/yr, these data suggest that extension across this plate boundary occurs episodically within the narrow (approx. 1 km) region of the axial valley floor, and that active deformation is occurring between the axial cleft and the plate interior. A cleft-parallel 714-m baseline located 300 m to the west of the cleft on the Pacific plate monitored system performance and, as expected, observed no motion (+5 ?? 7 mm/yr) between the 1994 and 1996 surveys.

  9. Transform push, oblique subduction resistance, and intraplate stress of the Juan de Fuca plate

    USGS Publications Warehouse

    Wang, K.; He, J.; Davis, E.E.

    1997-01-01

    The Juan de Fuca plate is a small oceanic plate between the Pacific and North America plates. In the southernmost region, referred to as the Gorda deformation zone, the maximum compressive stress a, constrained by earthquake focal mechanisms is N-S. Off Oregon, and possibly off Washington, NW trending left-lateral faults cutting the Juan de Fuca plate indicate a a, in a NE-SW to E-W direction. The magnitude of differential stress increases from north to south; this is inferred from the plastic yielding and distribution of earthquakes throughout the Gorda deformation zone. To understand how tectonic forces determine the stress field of the Juan de Fuca plate, we have modeled the intraplate stress using both elastic and elastic-perfectly plastic plane-stress finite element models. We conclude that the right-lateral shear motion of the Pacific and North America plates is primarily responsible for the stress pattern of the Juan de Fuca plate. The most important roles are played by a compressional force normal to the Mendocino transform fault, a result of the northward push by the Pacific plate and a horizontal resistance operating against the northward, or margin-parallel, component of oblique subduction. Margin-parallel subduction resistance results in large N-S compression in the Gorda deformation zone because the force is integrated over the full length of the Cascadia subduction zone. The Mendocino transform fault serves as a strong buttress that is very weak in shear but capable of transmitting large strike-normal compressive stresses. Internal failure of the Gorda deformation zone potentially places limits on the magnitude of the fault-normal stresses being transmitted and correspondingly on the magnitude of strike-parallel subduction resistance. Transform faults and oblique subduction zones in other parts of the world can be expected to transmit and create stresses in the same manner. Copyright 1997 by the American Geophysical Union.

  10. Juan Rulfo and Machado de Assis: Toward an Integrated New Narrative

    ERIC Educational Resources Information Center

    Wiseman, David P.; Krause, James R.

    2016-01-01

    Despite apparent connections between Brazilian and Spanish American narratives, comparative scholarship has only recently begun to investigate actively these important points of contact. In this study, we introduce a vital crossover between the two traditions, involving Juan Rulfo and Joaquim Maria Machado de Assis. Rulfo's outspoken affinity for…

  11. Maniac Talk - Dr. Marshall Shepherd

    NASA Image and Video Library

    2015-07-14

    Marshall Shepherd Maniac Lecture, July 14, 2015 Dr. Marshall Shepherd, professor, University of Georgia, also the host of Sunday's talk show Weather Geeks, presented a Maniac lecture entitled "Zombies, Sports, and Cola: Implications for Communicating Weather and Climate." Believe it or not, Dr. Shepherd ties zombies, sports, and cola together to provide a compelling look at how we communicate (miscommunicate) weather and climate.

  12. Impacts of Urbanization in the Coastal Tropical City of San Juan, Puerto Rico

    NASA Technical Reports Server (NTRS)

    Comarazamy, Daniel E.; Gonzalez, Jorge E.; Luvall, Jeffrey C.; Rickman, Douglass

    2007-01-01

    Urban sprawl in tropical locations is rapidly accelerating and it is more evident in islands where a large percentage of the population resides along the coasts. This paper focuses on the analysis of the impacts of land use and land cover for urbanization in the tropical coastal city of San Juan, in the Caribbean island of Puerto Rico. A mesoscale numerical model, the Regional Atmospheric Modeling System (RAMS), is used to study the impacts of land use for urbanization in the environment including specific characteristics of the urban heat island in the San Juan Metropolitan Area (SJMA), one of the most noticeable urban cores of the Caribbean. The research also makes use of the observations obtained during the airborne San Juan Atlas Mission. Surface and raw insonde data from the mission are used to validate the atmospheric model yielding satisfactory results. Airborne high resolution remote sensing data are used to update the model's surface characteristics in order to obtain a more accurate and detailed configuration of the SJMA and perform a climate impact analysis based on land cover/land use (LCLU) changes. The impact analysis showed that the presence of the urban landscape of San Juan has an impact reflected in higher air temperatures over the area occupied by the city, with positive values of up to 2.5 degrees C, for the simulations that have specified urban LCLU indexes in the model's bottom boundary. One interesting result of the impact analysis was the finding of a precipitation disturbance shown as a difference in total accumulated rainfall between the present urban landscape and with a potential natural vegetation, apparently induced by the presence of the urban area. Results indicate that the urban-enhanced cloud formation and precipitation development occur mainly downwind of the city, including the accumulated precipitation. This spatial pattern can be explained by the presence of a larger urbanized area in the southwest sector of the city, and of

  13. Impacts of Urbanization in the Coastal Tropical City of San Juan, Puerto Rico

    NASA Technical Reports Server (NTRS)

    Comarazamy, Daniel E.; Gonzalez, Jorge E.; Luvall, Jeffrey C.; Rickman, Douglas L.; Mulero, Pedro J.

    2007-01-01

    Urban sprawl in tropical locations is rapidly accelerating and it is more evident in islands where a large percentage of the population resides along the coasts. This paper focuses on the analysis of the impacts of land use and land cover for urbanization in the tropical coastal city of San Juan, in the Caribbean island of Puerto Rico. A mesoscale numerical model, the Regional Atmospheric Modeling System (RAMS), is used to study the impacts of land use for urbanization in the environment including specific characteristics of the urban heat island in the San Juan Metropolitan Area (SJMA), one of the most noticeable urban cores of the Caribbean. The research also makes use of the observations obtained during the airborne San Juan Atlas Mission. Surface and rawinsonde data from the mission are used to validate the atmospheric model yielding satisfactory results. Airborne high resolution remote sensing data are used to update the model's surface characteristics in order to obtain a more accurate and detailed configuration of the SJMA and perform a climate impact analysis based on land cover/land use (LCLU) changes. The impact analysis showed that the presence of the urban landscape of San Juan has an impact reflected in higher air temperatures over the area occupied by the city, with positive values of up to 2.5 C, for the simulations that have specified urban LCLU indexes in the model's bottom boundary. One interesting result of the impact analysis was the finding of a precipitation disturbance shown as a difference in total accumulated rainfall between the present urban landscape and with a potential natural vegetation, apparently induced by the presence of the urban area. Results indicate that the urban enhanced cloud formation and precipitation development occur mainly downwind of the city, including the accumulated precipitation. This spatial pattern can be explained by the presence of a larger urbanized area in the southwest sector of the city, and of the

  14. RG7386, a Novel Tetravalent FAP-DR5 Antibody, Effectively Triggers FAP-Dependent, Avidity-Driven DR5 Hyperclustering and Tumor Cell Apoptosis.

    PubMed

    Brünker, Peter; Wartha, Katharina; Friess, Thomas; Grau-Richards, Sandra; Waldhauer, Inja; Koller, Claudia Ferrara; Weiser, Barbara; Majety, Meher; Runza, Valeria; Niu, Huifeng; Packman, Kathryn; Feng, Ningping; Daouti, Sherif; Hosse, Ralf J; Mössner, Ekkehard; Weber, Thomas G; Herting, Frank; Scheuer, Werner; Sade, Hadassah; Shao, Cuiying; Liu, Bin; Wang, Peng; Xu, Gary; Vega-Harring, Suzana; Klein, Christian; Bosslet, Klaus; Umaña, Pablo

    2016-05-01

    Dysregulated cellular apoptosis and resistance to cell death are hallmarks of neoplastic initiation and disease progression. Therefore, the development of agents that overcome apoptosis dysregulation in tumor cells is an attractive therapeutic approach. Activation of the extrinsic apoptotic pathway is strongly dependent on death receptor (DR) hyperclustering on the cell surface. However, strategies to activate DR5 or DR4 through agonistic antibodies have had only limited clinical success. To pursue an alternative approach for tumor-targeted induction of apoptosis, we engineered a bispecific antibody (BsAb), which simultaneously targets fibroblast-activation protein (FAP) on cancer-associated fibroblasts in tumor stroma and DR5 on tumor cells. We hypothesized that bivalent binding to both FAP and DR5 leads to avidity-driven hyperclustering of DR5 and subsequently strong induction of apoptosis in tumor cells but not in normal cells. Here, we show that RG7386, an optimized FAP-DR5 BsAb, triggers potent tumor cell apoptosis in vitro and in vivo in preclinical tumor models with FAP-positive stroma. RG7386 antitumor efficacy was strictly FAP dependent, was independent of FcR cross-linking, and was superior to conventional DR5 antibodies. In combination with irinotecan or doxorubicin, FAP-DR5 treatment resulted in substantial tumor regression in patient-derived xenograft models. FAP-DR5 also demonstrated single-agent activity against FAP-expressing malignant cells, due to cross-binding of FAP and DR5 across tumor cells. Taken together, these data demonstrate that RG7386, a novel and potent antitumor agent in both mono- and combination therapies, overcomes limitations of previous DR5 antibodies and represents a promising approach to conquer tumor-associated resistance to apoptosis. Mol Cancer Ther; 15(5); 946-57. ©2016 AACR. ©2016 American Association for Cancer Research.

  15. 78 FR 18789 - Establishment of the San Juan Islands National Monument

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-28

    ... pinnacles known as the San Juan Islands. These islands form an unmatched landscape of contrasts, where... array of fossils and other evidence of long-vanished species. Ancient bison skeletons (10,000-12,000... boundaries described on the accompanying map, which is attached to and forms a part of this proclamation...

  16. The potential for alternative transportation at Chimney Rock, San Juan National Forest

    DOT National Transportation Integrated Search

    2012-05-30

    Increased visitation at Chimney Rock in the San Juan National Forest in southwest Colorado has led to increasing interest in the addition of a shuttle system. Piloting a shuttle system at Chimney Rock is a relatively low-cost option that the USFS cou...

  17. Dr. von Braun and Dr. Stuhlinger With a Model of the Nuclear-Electric Vehicles

    NASA Technical Reports Server (NTRS)

    2004-01-01

    In this photo, taken at the Walt Disney Studios in California, Dr. Wernher von Braun and Dr. Ernst Stuhlinger are shown discussing the concepts of nuclear-electric spaceships designed to undertake the mission to the planet Mars. As a part of the Disney 'Tomorrowland' series on the exploration of space, the nuclear-electric vehicles were shown in the last three television films, entitled 'Mars and Beyond,' which first aired in December 1957.

  18. Interview with Dr Ghassan K Abou-Alfa.

    PubMed

    Abou-Alfa, G K

    2016-11-01

    Ghassan K Abou-Alfa joined the Gastrointestinal Oncology Service at Memorial Sloan-Kettering Cancer Center and Weill Cornell Medical College in New York back in 2001. Dr Abou-Alfa specializes in the treatment of gastrointestinal malignancies. Dr Abou-Alfa received his medical degree from the American University of Beirut, Lebanon, and completed his post-doctoral training at Yale University School of Medicine. His research is dedicated to finding novel therapies and improving the effectiveness of the current therapies for hepatocellular carcinoma, cholangiocarcinoma and gallbladder cancer, while continuing to understand the basic mechanisms of the diseases and its therapy. Dr Abou-Alfa has invested several years in helping develop multi-tyrosine kinases and more immune-modulator therapies. Dr Abou-Alfa has many publications in the field. He led on many occasions international teams of investigators. Dr Abou-Alfa serves as the chair of the National Cancer Institute (NCI) Task Force for Hepatobiliary Cancers and the chair of the AIDS Malignancy Consortium (AMC) Non-AIDS Defining Malignancies (NADC) Liver/GI Task Force. Dr Abou-Alfa also co-chairs the hepatobiliary cancers subgroup of the Alliance cooperative group, and is a cadre member of both the gastrointestinal cancers and pharmacogenomics and population pharmacology committees. Dr Abou-Alfa who has lectured worldwide on the subject on gastrointestinal malignancies, is also a strong advocate for raising awareness and support for improving the outcome of patients with this disease, and enhancing oncologic education worldwide.

  19. ORAC-DR -- SCUBA Pipeline Data Reduction

    NASA Astrophysics Data System (ADS)

    Jenness, Tim; Economou, Frossie

    ORAC-DR is a flexible data reduction pipeline designed to reduce data from many different instruments. This document describes how to use the ORAC-DR pipeline to reduce data taken with the Submillimetre Common-User Bolometer Array (SCUBA) obtained from the James Clerk Maxwell Telescope.

  20. Strengthening the Community/Education Partnership: The San Juan RFD Model of Public Involvement. Public Involvement Using the Rural Futures Development Strategy.

    ERIC Educational Resources Information Center

    Rasmussen, Randy C.; Jensen, Carl

    San Juan School District, a rural school district in the southeast corner of Utah, implemented the Rural Futures Development (RFD) Strategy program to develop greater public involvement in the education process. Geographically one of the largest school districts (approximately 8,000 square miles) in the U.S., San Juan serves Anglos who mainly live…

  1. Knowledge to serve the city: insights from an emerging knowledge-action network to address vulnerability and sustainability in San Juan, Puerto Rico

    Treesearch

    T.A. Munoz-Erickson; A.E. Lugo; E. Melendez-Ackerman; L.E. Santiago-Acevedo; J. Seguinot-Barbosa; P. Mendez-Lazaro

    2014-01-01

    This paper presents initial efforts to establish the San Juan Urban Long-Term Research Area Exploratory (ULTRA-Ex), a long-term program aimed at developing transdisciplinary social-ecological system (SES) research to address vulnerability and sustainability for the municipality of San Juan. Transdisciplinary approaches involve the collaborations between researchers,...

  2. Understanding anthocyanin: Researcher and educator Dr. Ron Wrolstad

    USDA-ARS?s Scientific Manuscript database

    This invited presentation is in honor of Dr. Ronald E. Wrolstad (Distinguished Professor Emeritus), recipient of the 2017 ACS AGFD Advancement of the Application of Agricultural and Food Chemistry Award. The talk will be a brief overview of Dr. Ronald E. Wrolstad’s research program and career; Dr. W...

  3. Dengue Fever Trends and Climate Change in San Juan, Puerto Rico

    NASA Astrophysics Data System (ADS)

    Muller-Karger, F. E.; Mendez-Lazaro, P.; Otis, D. B.; McCarthy, M.; Pena-Orellana, M.

    2014-12-01

    Climate change has important implications for public health. We developed and tested the hypothesis that conditions for dengue fever transmission in San Juan (Puerto Rico, USA) are becoming favorable as a result of meteorological drivers being modified with climate change. Sea level pressure, mean sea level (MSL), wind, sea surface temperature (SST), air surface temperature (AST), rainfall, and confirmed dengue cases were variables examined over the past 30 years, or longer for some variables. Statistical tools used included Principal Component Analysis, Pearson correlation coefficient, Mann-Kendall trend tests, and logistic regressions. Results show that dry days are increasing and that wet days are decreasing. MSL is steadily increasing, which increases the risk of dengue cases along the coast, as the perimeter of the San Juan Bay estuary expands and the shoreline moves inland. Warming is evident in both SST and AST. Maximum and minimum air surface temperature extremes have also increased. Incidence of dengue is accelerating along with environmental change. For example, between 2000-2011, dengue transmission increased by a factor of 3.4 (95% CI: 1.9-6.1) for each 1ºC increase in SST. Between 2007 and 2011, this risk factor increased to 5.2 (95% CI: 1.9-13.9) for every 1ºC increase in SST. An important but difficult to examine problem is how social and economic factors affect such dengue fever transmission rates in light of environmental change. A concern is that the patterns observed in San Juan are representative of potential incidence of dengue virus in other parts of the island of Puerto Rico and in other Caribbean nations. These results help understand patterns of disease spreading, and allow public health officials to evaluate scenarios and interventions intended to mitigate the impacts of climate change.

  4. Quantification of Methane and Ethane Emissions from the San Juan Basin

    NASA Astrophysics Data System (ADS)

    Smith, M. L.; Kort, E. A.; Karion, A.; Sweeney, C.; Gvakharia, A.

    2015-12-01

    Methane (CH4), a potent greenhouse gas, and the primary component of natural gas, is emitted from areas of high fossil fuel production and processing. Recently, persistent and large methane emissions (~0.59 Tg yr-1) from the four corners area of the United States have been identified using satellite (SCIAMACHY) observations taken over the years 2003 to 2009. These emissions appear to be the largest CH4 anomaly (positive deviation above background values) in the contiguous U.S., and exceed bottom-up inventory estimates for the area by 1.8 to 3.5 times. The majority of emissions sources expected to contribute to this anomalous CH4 signal are located in the San Juan basin of New Mexico, and include harvesting and processing of natural gas, coal, and coalbed CH4. The magnitude of CH4 emissions from the San Juan basin have not yet been directly quantified using airborne measurements. Additionally, changing fossil fuel-related activities in the basin may have altered the magnitude of CH4 emissions compared to estimates derived from 2003-2009 satellite measurements. Here, we present in-situ airborne observations of CH4 over the San Juan basin, which allow tight quantification of CH4 fluxes using the mass balance method. Observations over the basin were taken for multiple wind directions on multiple days in April, 2015 to obtain a robust estimate of CH4 emissions. The flux of ethane (C2H6), the second most abundant component of natural gas and a tracer species indicative of fossil-derived CH4, was also quantified. Substantial C2H6 emissions may affect regional air quality and chemistry through its influence on tropospheric ozone production.

  5. Dry Juan de Fuca slab revealed by quantification of water entering Cascadia subduction zone

    NASA Astrophysics Data System (ADS)

    Canales, J. P.; Carbotte, S. M.; Nedimović, M. R.; Carton, H.

    2017-11-01

    Water is carried by subducting slabs as a pore fluid and in structurally bound minerals, yet no comprehensive quantification of water content and how it is stored and distributed at depth within incoming plates exists for any segment of the global subduction system. Here we use seismic data to quantify the amount of pore and structurally bound water in the Juan de Fuca plate entering the Cascadia subduction zone. Specifically, we analyse these water reservoirs in the sediments, crust and lithospheric mantle, and their variations along the central Cascadia margin. We find that the Juan de Fuca lower crust and mantle are drier than at any other subducting plate, with most of the water stored in the sediments and upper crust. Variable but limited bend faulting along the margin limits slab access to water, and a warm thermal structure resulting from a thick sediment cover and young plate age prevents significant serpentinization of the mantle. The dryness of the lower crust and mantle indicates that fluids that facilitate episodic tremor and slip must be sourced from the subducted upper crust, and that decompression rather than hydrous melting must dominate arc magmatism in central Cascadia. Additionally, dry subducted lower crust and mantle can explain the low levels of intermediate-depth seismicity in the Juan de Fuca slab.

  6. Conodont biostratigraphy from the upper San Juan Formation (Middle Ordovician) at Niquivil, Argentine Precordillera

    NASA Astrophysics Data System (ADS)

    Mango, M. J.; Albanesi, G. L.

    2018-07-01

    The present work deals with the conodont biostratigraphy from the upper San Juan Formation in the section of Niquivil, Central Precodillera of San Juan, Argentina. We study the upper 129.45 m of the San Juan Formation, starting from the upper strata of the second reef horizon up to the top of the formation. Digested limestone samples yielded 20 conodont species. The presence of Tripodus laevis Bradshaw not associated to Baltoniodus navis (Lindström) allows the recognition of the Baltoniodus triangularis-Tripodus laevis Zone, which is interpreted as correlative with the "Parapanderodus" nogamii/Parapanderodus gracilis/Ansella jemtlandica Association of Lehnert (1993, 1995; Lehnert and Keller, 1993), conversely to previous interpretations that suggested the latter as correlative to the Baltoniodus navis Zone. The zonal identification is supported by the associated conodonts Protopanderodus rectus (Lindström), Juanognathus jaanussoni Serpagli, Juanognathus n. sp., Protopanderodus gradatus (Serpagli), Rossodus barnesi Albanesi, Paltodus subaequalis Pander, Drepanodus arcuatus (Pander), Cornuodus longibasis (Lindström), Protopanderodus elongatus Serpagli, Oistodus lanceolatus Pander, Periodon flabellum (Lindström), Semiacontiodus potrerillensis Albanesi, Triangulodus brevibasis (Sergeeva), Paroistodus originalis (Sergeeva), Drepanoistodus forceps (Lindström), Oistodus multicorrugatus Harris, Parapanderodus paracornuformis (Ethington and Clark), Anodontus longus Stouge and Bagnoli, and Pteracontiodus cryptodens Mound. The petrographic microscope analysis of carbonate rocks thin sections refer to proximal middle ramp deposits.

  7. PREFACE: XIV Mexican School on Particles and Fields

    NASA Astrophysics Data System (ADS)

    Bashir, Adnan; Contreras, Guillermo; Raya, Alfredo; Tejeda-Yeomans, Maria Elena

    2011-03-01

    de Física de Altas Energías. At a personal level, we are very grateful to Dr Juan Carlos D'Olivo (President of the Red Nacional de Física de Altas Energías), Dr Pedro Mata Vázquez (Director of COECyT), Dr Ricardo Becerril Bárcenas (Director of the Institute of Physics and Mathematics, UMSNH), Dr Rigoberto Vera Mendoza (Director of the Faculty of Science, UMSNH) and Dr José Napoleón Guzmán Ávila (Coordinator of Scientific Research, UMSNH) for their invaluable support in all organizational matters, which enabled the school to become a reality. We gratefully acknowledge the help of our colleagues in the organizing committee: Alexis Aguilar, Alejandro Ayala, Wolfgang Bietenholz, Alberto Güijosa, Gabriela Murguía, Sarira Sahu (UNAM), Eduard de la Cruz Burelo, Abdel Pérez-Lorenzana (CINVESTAV), Elena Cáceres (UCOL), David Delepine (UG), Mariana Kirchbach (UASLP), Ildefonso León (UAS), Juan Carlos Arteaga-Velázquez (for his impeccable work in managing the web page of the school) and Víctor Villanueva (UMSNH). Most of them contributed to the extra work involved in refereeing the contributions submitted for this publication. Many thanks also go to all the student volunteers for the efficiency and dedication with which they carried out their duties. At the registration desk, we relied on the hard work of Xiomara Gutiérrez, Enif Gutiérrez (UMSNH) and Mara Diaz Pancardo. Several post docs and PhD students provided invaluable support in all organizational matters: Adolfo Huet, Cliffor Compeán, Rocío Bermúdez, Saúl Sánchez, Anabel Trejo, Iraís Rubalcava, Khépani Raya, José Juan González, Saúl Hernández Ortiz (UMSNH), Alfredo Galaviz, and Alan Aganza (USON). Their help in carrying out the organization of the school was essential and without their collaboration, this school would not have been the same. We also acknowledge the help of the administrative secretary Maria Esperanza Jaramillo of IFM (UMSNH). We would like to take this opportunity to thank

  8. The genus Apodrosus Marshall, 1922 in Cuba (Coleoptera, Curculionidae, Entiminae, Polydrusini)

    PubMed Central

    Anderson, Robert S.; Zhang, Guanyang

    2017-01-01

    Abstract The genus Apodrosus Marshall is newly recorded for, and revised for Cuba. Nine new species are recognized as follows: Apodrosus alberti (type locality, Granma, Parque Nacional Pico Turquino), A. alternatus (type locality, Guantánamo, El Yunque), A. franklyni (type locality, Cienfuegos, Parque Nacional Pico San Juan), A. griseus (type locality, Santiago de Cuba, Siboney-Jutici Ecological Reserve), A. mensurensis (type locality, Holguin, Parque Nacional La Mensura-Piloto), A. pseudoalternatus (type locality, Matanzas, Varahicacos), A. beckeli (type locality, Guantánamo, 8 km W. Imias), A. sandersoni (type locality, Guantánamo, Loma Lafarola), and A. zayasi (type locality, Cienfuegos, Parque Nacional Pico San Juan). A key for their identification, descriptions, summaries of natural history information and data on distributions are presented. A molecular phylogeny based on 11 species of Apodrosus from Cuba, Hispaniola and Puerto Rico is reconstructed. A sister group relationship between Polydrusus and Apodrosus is recovered with a limited sampling of the former genus. The monophyly of Apodrosus is recovered with strong support. Cuban Apodrosus are not monophyletic. Five of the six sampled Cuban species form a clade, sister to an undescribed Apodrosus species from the Dominican Republic; and, Apodrosus alternatus is sister to A. quisqueyanus Girón & Franz, 2010, a species from the Dominican Republic. Biogeographic implications for Cuban species are discussed in light of the phylogeny. PMID:28769710

  9. Estimates of ground-water recharge from precipitation to glacial-deposit and bedrock aquifers on Lopez, San Juan, Orcas, and Shaw islands, San Juan County, Washington

    USGS Publications Warehouse

    Orr, Laura A.; Bauer, Henry H.; Wayenberg, Judith A.

    2002-01-01

    An important source of fresh water on Lopez, San Juan, Orcas, and Shaw Islands in San Juan County off the northwestern coast of Washington is glacial-deposit and bedrock aquifers. Two methods were used to estimate recharge from precipitation to the water tables on the islands. A daily near-surface water-balance method, the Deep Percolation Model (DPM), was used to simulate water budgets for the period October 1, 1996, through September 30, 1998 (water years 1997-98) for six small drainage basins?three on Lopez Island and one each on San Juan, Orcas, and Shaw Islands. The calibrated soil and subsoil parameters from the DPM for each small basin were then used in island-wide applications of the DPM where the direct runoff component (which is not available on an island-wide basis) was simulated, rather than input, and calibration was not required. A spatial distribution of annual recharge was simulated for each island, with island averages of: Lopez Island, 2.49 inches per year; San Juan Island, 1.99 inches per year; Orcas Island, 1.46 inches per year; and Shaw Island, 1.44 inches per year.A chloride mass-balance method that requires measurements of atmospheric chloride deposition, precipitation, streamflow, and chloride concentrations in ground water was used to estimate recharge to the glacial-deposit aquifers of Lopez Island. Only average recharge could be estimated using this method rather than area-specific recharge. Average recharge for Lopez Island estimated by this method was only 0.63 inch per year. The range of chloride concentrations in ground-water samples from selected wells indicates that the average recharge in areas of glacial deposits is between 0.29 and 1.95 inches per year. Recharge simulated using the DPM for two drainage basins on Lopez Island overlain by glacial deposits are 2.76 and 2.64 inches per year. Sources of chloride in ground water other than from the atmosphere would cause the recharge estimated by the chloride mass-balance method to be

  10. Dr. Francis Collins Is New NIH Director

    MedlinePlus

    ... Current Issue Past Issues Dr. Francis Collins Is New NIH Director Past Issues / Summer 2009 Table of ... of this page please turn Javascript on. The new NIH Director, Dr. Francis Collins, served as Director ...

  11. DR Reactor VSR channel damage

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kempf, F.J.; Rawlins, J.K.

    1961-10-30

    On July 11, 1961 the Ball 3X System at DR Reactor was inadventently tripped. All vertical safety rods dropped and all channels were filled with balls. This report has the twofold purpose of documenting borescope observations of ten vertical rod channels at DR Reactor and recording the estimated extent of graphite damage resulting from the above incident. Channel damage data are presented on appended drawings. With suitable notations, the tracings of these drawings may be revised to reflect any future graphite damage. All vertical rod channels at DR Reactor were visually examined with a closed circuit television system during ballmore » removal efforts. Typical photographs of trapped balls and ledges, as viewed on the television monitor, are shown. Photographs of typical graphite damage, obtained through the borescope are also included in this report. 3 refs., 8 figs., 1 tab.« less

  12. ORAC-DR -- SCUBA-2 Pipeline Data Reduction

    NASA Astrophysics Data System (ADS)

    Gibb, Andrew G.; Jenness, Tim

    The ORAC-DR data reduction pipeline is designed to reduce data from many different instruments. This document describes how to use ORAC-DR to process data taken with the SCUBA-2 instrument on the James Clerk Maxwell Telescope.

  13. Juan de Fuca slab geometry and its relation to Wadati-Benioff zone seismicity

    USGS Publications Warehouse

    McCrory, Patricia A.; Blair, J. Luke; Waldhause, Felix; Oppenheimer, David H.

    2012-01-01

    A new model of the subducted Juan de Fuca plate beneath western North America allows first-order correlations between the occurrence of Wadati-Benioff zone earthquakes and slab geometry, temperature, and hydration state. The geo-referenced 3D model, constructed from weighted control points, integrates depth information from earthquake locations and regional seismic velocity studies. We use the model to separate earthquakes that occur in the Cascadia forearc from those that occur within the underlying Juan de Fuca plate and thereby reveal previously obscured details regarding the spatial distribution of earthquakes. Seismicity within the slab is most prevalent where the slab is warped beneath northwestern California and western Washington suggesting that slab flexure, in addition to expected metamorphic dehydration processes, promotes earthquake occurrence within the subducted oceanic plate. Earthquake patterns beneath western Vancouver Island are consistent with slab dehydration processes. Conversely, the lack of slab earthquakes beneath western Oregon is consistent with an anhydrous slab. Double-differenced relocated seismicity resolves a double seismic zone within the slab beneath northwestern California that strongly constrains the location of the plate interface and delineates a cluster of seismicity 10 km above the surface that includes the 1992 M7.1 Mendocino earthquake. We infer that this earthquake ruptured a surface within the Cascadia accretionary margin above the Juan de Fuca plate. We further speculate that this earthquake is associated with a detached fragment of former Farallon plate. Other subsurface tectonic elements within the forearc may have the potential to generate similar damaging earthquakes.

  14. Lightcurves from the Archive: 1090 Sumida, 2284 San Juan, and 3493 Stepanov

    NASA Astrophysics Data System (ADS)

    Lang, Kim

    2017-01-01

    Three asteroids were observed briefly between other projects in 2015 March and April. The lightcurves of 1090 Sumida and 3493 Stepanov shows amplitudes of A = 0.30 and A = 0.95 mag. For 2284 San Juan, a synodic period of P = 9.18 h and amplitude of A = 0.69 mag were found.

  15. Dr. Irene Sänger-Bredt, a life for astronautics

    NASA Astrophysics Data System (ADS)

    Zaganescu, Nicolae-Florin

    2004-12-01

    Irene Bredt (b.1911 at Bonn) obtained her Doctorate in Physics in 1937; in the same year she became a scientific researcher at the German Research Center for Aviation at Trauen, led by Prof. Dr. Eugen Sänger. Soon, the young but efficient Dr. Irene Bredt became the first assistant of Dr. Sänger, who married her (1951). During 1973-1978, Dr. Bredt was in correspondence with Prof. Dr. Nikolae-Florin Zaganescu and helped him to familiarize the Romanian readers with Prof. Sänger's life and achievements. As for Dr. Bredt's life, she specified three main periods of her activity: 1937-1942, when she was researcher in charge of thermodynamic problems of liquid-fuelled rocket engines at Trauen 1942-1945, when she was Senior Researcher in charge of Ramjet in flight performances at Ainring, and also coauthored the Top Secret Technical report entitled 'A Rocket Engine for a Long-Range Bomber', which was finished in 1941 but edited only in 1944 the post world war II period, when she was Scientific Advisor or Director at various civil and military research institutes, universities, etc. Dr. Irene Sänger-Bredt helped her husband to develop many scientific theories like Ramjet thermodynamic theory, and photon rocket theory and also in establishing IAF and IAA. In 1970, Dr. Irene Sänger-Bredt was honored with 'Hermann Oberth Gold Medal' for her impressive scientific activity.

  16. Goldie Brangman Remembers the Operation to Save Dr King.

    PubMed

    Koch, Evan; Brangman, Goldie

    2015-12-01

    In September 1958 the Rev Dr Martin Luther King Jr was stabbed and nearly assassinated. Surgeons at Harlem Hospital in New York City removed a 17.8-cm (7-in)-long letter opener from Dr King's chest. Certified Registered Nurse Anesthetist Goldie Brangman remembers this event because she participated in Dr King's anesthetic. This article correlates Brangman's memories with published accounts of the event. It also places the event within the context of the modern civil rights movement that Dr King led.

  17. A synoptic climatology of desert dust deposition to the alpine snowpack in the San Juan Mountains, Colorado, U.S.A.

    NASA Astrophysics Data System (ADS)

    McBride, K.; Painter, T.; Landry, C.

    2005-12-01

    Currently, collaborative research is underway in the San Juan Mountains to study the radiative and hydrologic effects of desert dust deposits in alpine snow. The component described here will present preliminary results of the development of a synoptic climatology for winter and spring dust deposition to the alpine snowpack in the San Juan Mountains of southwest Colorado. An understanding of the climatology of dust deposition events will improve our capacity to infer the temporal persistence and magnitude of dust deposition and ultimately its effect on hydrologic and ecological processes in the San Juan Mountains. We use the Stochastic Time-Inverted Lagrangian Transport (STILT) model to determine back and forward trajectories of air parcels. The input data were collected at the Putney Data site (3757 m) which has been in use for over 30 years and provides 'free air' wind data as well as ridge crest air temperatures and humidity. Putney lies 2 km SE of the Swamp Angel Study Plot, east of US Highway 550 at Red Mountain Pass. The Swamp Angel Study Plot is one of two extensively instrumented energy balance and radiation sites used in the study and operated by the Center for Snow and Avalanche Studies (CSAS). STILT outputs 3-dimensional probability distributions that describe the potential source regions for air parcels reaching the San Juan Mountains at known times of dust deposition. We analyze 11 dust deposition events that have been documented in snow in the San Juan Mountains or Elk Range of Colorado. One isolated dust event was documented in 1999 in the Elk Range. Subsequently, we have documented the dust deposition events in winters and springs of 2003, 2004, and 2005 in the San Juan Mountains. 2003 and 2004 experienced 3 dust events each but in 2003 the events came in February and April, whereas in 2004 the events came in late April and mid-May. In 2005, of the 4 dust events, the first came in late March, the second and third in early April, and the fourth in

  18. Dr. Goddard and a 1918 version of 'Bazooka'

    NASA Technical Reports Server (NTRS)

    2004-01-01

    Dr. Robert H. Goddard loading a 1918 version of the Bazooka of World War II. From 1930 to 1941, Dr. Goddard made substantial progress in the development of progressively larger rockets, which attained altitudes of 2400 meters, and refined his equipment for guidance and control, his techniques of welding, and his insulation, pumps, and other associated equipment. In many respects, Dr. Goddard laid the essential foundations of practical rocket technology

  19. El Programa Nacional de Estuarios (NEP)

    EPA Pesticide Factsheets

    Información general sobre el Programa Nacional de Estuarios (PNE, por sus siglas en inglés) establecido en el 1987 para restaurar y proteger los estuarios significativos para Estados Unidos, y sus territorios. La Agencia de Protección Ambiental de EE.UU.

  20. Towards a National Hazard Map of Landslides: Juan de Grijalva, Chiapas, and Mitlatongo, Oaxaca, two catastrophic landslides on southeastern of Mexico

    NASA Astrophysics Data System (ADS)

    Dominguez-M, L.; Castañeda, A.; Ramirez, A.; González, A. E.

    2013-05-01

    and represent two of the most outstanding and representative events in southeastern Mexico. Domínguez L., 2008 "El deslizamiento del 4 de noviembre de 2007 en la comunidad Juan de Grijalva, municipio de Ostuacán, Chiapas, y su relación con el Frente Frio no. 4" Report prepared to the General Coordination of Civil Protection, Ministry of the Interior, Mexico Centro Nacional de Prevención de Desastres, 2009 "Características e impacto socioeconómico de los principales desastres ocurridos en la República Mexicana en el año 2007" Socieconomic Impact by Disasters in Mexico Serie, National System of Civil Protection, Ministry of the Interior, Mexico. Domínguez L., 2011 "Deslizamiento de suelos y rocas en las comunidades de Santiago Mitlatongo, municipio de Nochixtlán, y Santa Cruz Mitlatongo, municipio de Magdalena Jaltepec, Oaxaca" Report prepared to the General Coordination of Civil Protection, Ministry of the Interior, Mexico.

  1. Sediment and water chemistry of the San Juan River and Escalante River deltas of Lake Powell, Utah, 2010-2011

    USGS Publications Warehouse

    Hornewer, Nancy J.

    2014-01-01

    Recent studies have documented the presence of trace elements, organic compounds including polycyclic aromatic hydrocarbons, and radionuclides in sediment from the Colorado River delta and from sediment in some side canyons in Lake Powell, Utah and Arizona. The fate of many of these contaminants is of significant concern to the resource managers of the National Park Service Glen Canyon National Recreation Area because of potential health impacts to humans and aquatic and terrestrial species. In 2010, the U.S. Geological Survey began a sediment-core sampling and analysis program in the San Juan River and Escalante River deltas in Lake Powell, Utah, to help the National Park Service further document the presence or absence of contaminants in deltaic sediment. Three sediment cores were collected from the San Juan River delta in August 2010 and three sediment cores and an additional replicate core were collected from the Escalante River delta in September 2011. Sediment from the cores was subsampled and composited for analysis of major and trace elements. Fifty-five major and trace elements were analyzed in 116 subsamples and 7 composited samples for the San Juan River delta cores, and in 75 subsamples and 9 composited samples for the Escalante River delta cores. Six composited sediment samples from the San Juan River delta cores and eight from the Escalante River delta cores also were analyzed for 55 low-level organochlorine pesticides and polychlorinated biphenyls, 61 polycyclic aromatic hydrocarbon compounds, gross alpha and gross beta radionuclides, and sediment-particle size. Additionally, water samples were collected from the sediment-water interface overlying each of the three cores collected from the San Juan River and Escalante River deltas. Each water sample was analyzed for 57 major and trace elements. Most of the major and trace elements analyzed were detected at concentrations greater than reporting levels for the sediment-core subsamples and composited

  2. Childhood Picture of Dr. von Braun

    NASA Technical Reports Server (NTRS)

    1912-01-01

    This is a childhood picture of Dr. von Braun (center) with his brothers. Dr. Wernher von Braun was born in Wirsitz, Germany, March 23, 1912. His childhood dreams of marned space flight were fulfilled when giant Saturn rockets, developed under his direction at NASA's Marshall Space Flight Center, boosted the manned Apollo spacecraft to the Moon. His life was dedicated to expanding man's knowledge through the exploration of space.

  3. Enhancing Price Response Programs through Auto-DR: California's 2007 Implementation Experience

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kiliccote, Sila; Wikler, Greg; Chiu, Albert

    2007-12-18

    This paper describes automated demand response (Auto-DR) activities, an innovative effort in California to ensure that DR programs produce effective and sustainable impacts. Through the application of automation and communication technologies coupled with well-designed incentives and DR programs such as Critical Peak Pricing (CPP) and Demand Bidding (DBP), Auto-DR is opening up the opportunity for many different types of buildings to effectively participate in DR programs. We present the results of Auto-DR implementation efforts by the three California investor-owned utilities for the Summer of 2007. The presentation emphasizes Pacific Gas and Electric Company's (PG&E) Auto-DR efforts, which represents the largestmore » in the state. PG&E's goal was to recruit, install, test and operate 15 megawatts of Auto-DR system capability. We describe the unique delivery approaches, including optimizing the utility incentive structures designed to foster an Auto-DR service provider community. We also show how PG&E's Critical Peak Pricing (CPP) and Demand Bidding (DBP) options were called and executed under the automation platform. Finally, we show the results of the Auto-DR systems installed and operational during 2007, which surpassed PG&E's Auto-DR goals. Auto-DR is being implemented by a multi-disciplinary team including the California Investor Owned Utilities (IOUs), energy consultants, energy management control system vendors, the Lawrence Berkeley National Laboratory (LBNL), and the California Energy Commission (CEC).« less

  4. The HLA-DRB9 gene and the origin of HLA-DR haplotypes.

    PubMed

    Gongora, R; Figueroa, F; Klein, J

    1996-11-01

    HLA-DRB9 is a gene fragment consisting of exon 2 and flanking intron sequences. It is located at the extreme end of the DRB subregion, whose other end is demarcated by the DRB1 locus. We sequenced approximately 1400 base pairs of the segment encompassing the DRB9 locus from eight human haplotypes (DR1, DR10, DR2, DR3, DR5, DR6, DR8, and DR9, the DR4 and DR7 having been sequenced by others earlier), as well as two chimpanzee, five gorillas, one orangutan and one macaque haplotype. The analysis of these sequences indicates that the DRB9 locus, which we estimate to be more than 58 million years (my) old, has been coevolving with the DRB1 locus for the last 4.2 my. As a consequence of this coevolution, the human DRB9 alleles fall into groups that correlate with the DRB1 allelic groups and with the gene organization of the human haplotypes. This observation implies that the present-day HLA-DR haplotype groups (DR1, DR51, DR52, DR8, and DR53) were founded more than 4 my ago and have remained intact (barring minor internal rearrangements that did not recombine the DRB1 and DRB9 genes) for this period of time. The haplotypes have been transmitted during speciations from ancestral to emerging species just like allelic lineages at the DRB1 locus. Thus not only allelic but also haplotype polymorphism evolves trans-specifically.

  5. Gaia DR2 documentation Chapter 7: Variability

    NASA Astrophysics Data System (ADS)

    Eyer, L.; Guy, L.; Distefano, E.; Clementini, G.; Mowlavi, N.; Rimoldini, L.; Roelens, M.; Audard, M.; Holl, B.; Lanzafame, A.; Lebzelter, T.; Lecoeur-Taïbi, I.; Molnár, L.; Ripepi, V.; Sarro, L.; Jevardat de Fombelle, G.; Nienartowicz, K.; De Ridder, J.; Juhász, Á.; Molinaro, R.; Plachy, E.; Regibo, S.

    2018-04-01

    This chapter of the Gaia DR2 documentation describes the models and methods used on the 22 months of data to produce the Gaia variable star results for Gaia DR2. The variability processing and analysis was based mostly on the calibrated G and integrated BP and RP photometry. The variability analysis approach to the Gaia data has been described in Eyer et al. (2017), and the Gaia DR2 results are presented in Holl et al. (2018). Detailed methods on specific topics will be published in a number of separate articles. Variability behaviour in the colour magnitude diagram is presented in Gaia Collaboration et al. (2018c).

  6. VizieR Online Data Catalog: KODIAQ DR2 (O'Meara+, 2017)

    NASA Astrophysics Data System (ADS)

    O'Meara, J. M.; Lehner, N.; Howk, J. C.; Prochaska, J. X.; Fox, A. J.; Peeples, M. S.; Tumlinson, J.; O'Shea, B. W.

    2018-02-01

    The new data presented here in DR2 all stem from High-Resolution Echelle Spectrograph (HIRES) observations by multiple PIs between 1995 and 2004. Table1 presents the HIRES deckers used across DR2 and their corresponding spectral resolution. As with DR1, the majority of observations were made with the C1 or C5 decker providing ~6 and ~8km/s FWHM resolution, respectively. The Keck Observatory Database of Ionized Absorption toward Quasars (KODIAQ) DR2 comprises HIRES observations of 300 quasar lines of sight in total. Of these, 130 quasar sight lines are new since DR1 (O'Meara et al. 2015, Cat. J/AJ/150/111), along with many new additional observations of some of the DR1 quasars. Table2 presents the new data since DR1. Table3 presents the full DR2 sample of 300 quasars. (3 data files).

  7. The geology and distribution of aquifers in the southeastern part of San Juan County, Utah

    USGS Publications Warehouse

    Goode, Harry D.

    1958-01-01

    The structural geology and the distribution of aquifers in the southeastern part of San Juan County were studied to establish the relationships of fresh-water aquifers to the oil- and gas-bearing rocks in that area.

  8. Teaching medicine with the help of "Dr. House".

    PubMed

    Jerrentrup, Andreas; Mueller, Tobias; Glowalla, Ulrich; Herder, Meike; Henrichs, Nadine; Neubauer, Andreas; Schaefer, Juergen R

    2018-01-01

    TV series such as "House MD", "Grey´s Anatomy" or "Emergency Room" are well perceived by medical students. Seminars featuring medical TV series such as "House MD" might serve as door-opener to attract medical students to learn more about rare diseases. The TV series "House MD" is troublesome for the main character Dr. House is an excellent diagnostician but at the same time a rather misanthropic person. Therefore, lecturing medicine with the help of "House MD" requires constant evaluation. From 2008 to 2016 we are using the well-known TV series "House MD" continuously to attract medical students and teach them about rare diseases as well as diagnostic strategies. We collected from 213 students a detailed questionnaire assessing their learning experience. 76.6% of our students (n = 157) reported to watching medical dramas on a regular basis. The Dr. House seminar was compared to traditional seminars and our students reported an improved learning effect (69.9%), better concentration (89.7%), higher motivation to participate (88.7%), and more fun (86.7%) (all p<0.001). The students see Dr. House's behavior quite critically. Likert assessment on a 5-point scale identified strong disagreement with Dr. House´s interpersonal skills in dealing with his colleagues (median = 1) and patients (median = 1). At the same time, the students strongly agreed with his outstanding diagnostic (median = 5) and therapeutic capabilities (median = 4). Medical students visiting a Dr. House teaching seminar are highly motivated to learn more about rare diseases. They were positively influenced by TV series such as Dr. House to improve their diagnostic and clinical skills. At the same time, they are critical enough not to see Dr. House as a role model for their own personality. Well performed medical TV shows such as Dr. House can successfully be used in an educational setting to motivate medical students to come into seminars to learn more about rare diseases.

  9. Defense.gov Special Report: Dr. Jill Biden

    Science.gov Websites

    . "I feel like you are my extended family." Story More Stories Dr. Biden Welcomes Guard Children Support Bidens Welcome Soldiers Home at Fort Drum Military Children Deserve America's Support Dr. Biden Guard Children Bidens Visit Iraq for Fourth Festivities More Photo Essays Bidens Welcome Troops Home at

  10. Dr. von Braun Tries Out the NBS

    NASA Technical Reports Server (NTRS)

    1967-01-01

    Marshall Space Flight Center (MSFC) Director, Dr. von Braun, is shown fitted with suit and diving equipment as he prepares for a tryout in the MSFC Neutral Buoyancy Simulator (NBS). Weighted to a neutrally buoyant condition, Dr. von Braun was able to perform tasks underwater which simulated weightless conditions found in space.

  11. 33 CFR 167.1315 - In the Strait of Juan de Fuca: Precautionary area “PA.”

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY OFFSHORE TRAFFIC SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Pacific West Coast § 167.1315 In the Strait of Juan de...

  12. 33 CFR 167.1315 - In the Strait of Juan de Fuca: Precautionary area “PA.”

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY OFFSHORE TRAFFIC SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Pacific West Coast § 167.1315 In the Strait of Juan de...

  13. 33 CFR 167.1315 - In the Strait of Juan de Fuca: Precautionary area “PA.”

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY OFFSHORE TRAFFIC SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Pacific West Coast § 167.1315 In the Strait of Juan de...

  14. 33 CFR 167.1315 - In the Strait of Juan de Fuca: Precautionary area “PA.”

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY OFFSHORE TRAFFIC SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Pacific West Coast § 167.1315 In the Strait of Juan de...

  15. SAN JUAN BAY ESTUARY PROGRAM COMPREHENSIVE CONSERVATION AND MANAGEMENT PLAN IMPLEMENTATION TRACKING REPORT, 2004

    EPA Science Inventory

    Four years after the approval of its Comprehensive Conservation and Management Plan (CCMP), the San Juan Bay Estuary Program (SJBEP) is working towards the implementation stage of its 49 actions. During the last three years the program has focused its efforts in developing a coll...

  16. Dr. Albert Carr--Science Educator 1930-2000

    ERIC Educational Resources Information Center

    Lopez, Leslie

    2013-01-01

    The very first issue of "Educational Perspectives" was published in October of 1962. Dr. Albert Carr wrote one of the inaugural essays on the topic of current developments in science education, and he went on to write several other articles for the journal. This article shares why Dr. Albert Carr's colleagues remember him for his…

  17. When "The Cure" Is the Risk: Understanding How Substance Use Affects HIV and HCV in a Layered Risk Environment in San Juan, Puerto Rico

    ERIC Educational Resources Information Center

    Hernández, Diana; Castellón, Pedro C.; Fernández, Yohansa; Torres-Cardona, Francisco A.; Parish, Carrigan; Gorshein, Danielle; Vargas Vidot, Jose; Miranda de Leon, Sandra; Rodriguez, Allan; Santana Bagur, Jorge; Feaster, Daniel J.; Schackman, Bruce R.; Metsch, Lisa R.

    2017-01-01

    Background: Substance use, particularly injection drug use, continues to fuel the HIV/HCV (hepatitis C virus) epidemics in San Juan, Puerto Rico (PR). Aim: This article examines individual and sociostructural factors that affect HIV/HCV risk among people who use drugs (PWUD) living with or at risk for HIV/HCV in San Juan, PR. Findings were used to…

  18. Dr. Zakir Husain on Education and Language

    ERIC Educational Resources Information Center

    Kumar, Deepak; Radha Gayathri, Ch.

    2017-01-01

    Dr. Zakir Husain is known as a self-less nationalist leader and also as an educationist "par excellence." Taking a cue from his educational ideas like the "Nai Talim," this article brings into focus his views on the medium-conundrum. Dr. Husain was very clear about the role of Indian languages and the relevance of mother…

  19. Effects of Desert Dust on Nutrient Cycling in the San Juan Mountains, Colorado

    NASA Astrophysics Data System (ADS)

    Neff, J. C.; Farmer, L.; Painter, T. H.; Landry, C.; Reynolds, R.

    2005-12-01

    The San Juan Mountains of southwestern Colorado lie downwind from several major deserts and experience several dust-deposition events each year. These events appear related to storms that erode soils in the deserts of the western US and then deposit atmospheric dust from these soils during or after snowfall during large late winter and spring deposition events. To evaluate the biogeochemical implications of eolian deposition, we collected dust from distinct layers deposited into the seasonal snowpack. We also sampled soils and lake sediments in a high-elevation catchment in the San Juan Mountains. Atmospheric dust was characterized by measurements of chemical composition, Sr isotopic content and analysis of the organic and inorganic constituents of deposited eolian material. The origins of snowpack dust in the San Juans were analyzed using atmospheric tracer transport modeling. These analyses suggest that many dust events originate in southern Utah and northern Arizona, areas that have undergone substantial land use change through the 20th century and that experience severe wind erosion of soils during periodic severe droughts. Analyses of 87Sr/86Sr isotope ratios dust, soils, bedrock, and sediments suggest that eolian dust may compose as much as 90% of the near-surface soil (top 5 cm). In alpine lake sediments, Sr isotopes suggest a relatively recent (20th century) increase in the fraction of sediments derived from dust (relative to bedrock) and a similarly large contribution of dust to surface sediments. Sediment chemistry in two small alpine tarns show changes in Ca, Mg, Al, and Fe concentrations that imply increasing dust (vs. bedrock) contributions to lake sediments over the past 100-200 years. Increasing loading of Ca, Mg and P to alpine basins may have implications for alpine and sub-alpine biogeochemical cycling including water quality and plant nutrient use.

  20. Propagation as a mechanism of reorientation of the Juan de Fuca ridge

    NASA Technical Reports Server (NTRS)

    Wilson, D. S.; Hey, R. N.; Nishimura, C.

    1984-01-01

    A revised model is presented of the tectonic evolution of the Juan de Fuca ridge by propagating rifting. The new model has three different relative rotation poles, covering the time intervals 17.0-8.5 Ma, 8.5-5.0 Ma, and 5.0 Ma to the present. The rotation pole shifts at 8.5 and 5.0 Ma imply clockwise shifts in the direction of relative motion of 10 deg to 15 deg. At each of these shifts, the pattern of propagation reorganizes, and the new ridges formed by propagation are at an orientation closer to orthogonal to the new direction of motion than the orientation of the preexisting ridges. The model, containing a total of seven propagation sequences, shows excellent agreement with the isochrons inferred from the magnetic anomaly data, except in areas complicated by the separate Explorer and Gorda plates. The agreement between model and data near the Explorer plate breaks down abruptly at an age of about 5 Ma, indicating that the probable cause of the rotation pole shift at that time was the separation of the Explorer plate from the Juan de Fuca plate.

  1. 77 FR 52310 - Expansion of Foreign-Trade Zone 61, San Juan, Puerto Rico

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-29

    ... 61, San Juan, Puerto Rico Pursuant to its authority under the Foreign-Trade Zones Act of June 18... Order: Whereas, the Puerto Rico Trade and Export Company, grantee of Foreign-Trade Zone 61, submitted an application to the Board for authority to expand FTZ 61 to include a site in Aguadilla, Puerto Rico, adjacent...

  2. Geochemical variability of natural soils and reclaimed minespoil soils in the San Juan Basin, New Mexico

    USGS Publications Warehouse

    Gough, L.P.; Severson, R.C.

    1981-01-01

    An inventory of total-and extractable-element concentrations in soils was made for three areas of the San Juan Basin in New Mexico: (1) the broad area likely to be affected by energy-related development. (2) an area of soils considered to have potential for use as topsoil in mined-land reclamation. and (3) an area of the San Juan coal mine that has been regraded. topsoiled, and revegetated. Maps made of concentrations of 16 elements in area 1 soils show no gradational pattern across the region. Further. these maps do not correspond to those showing geology or soil types. Sodic or saline problems, and a possible but unproven deficiency of zinc available to plants. may make some of the soils in this area undesirable for use as topsoil in mined-land reclamation. Taxonomic great groups of soil in this area cannot be distinguished because each great group tends to have a large within-group variability if compared to the between-group variability. In area 2 the major soils sampled were of the Sheppard. Shiprock. and Doak association. These soils are quite uniform in chemical composition and are not greatly saline or sodic. As in area 1 soils. zinc deficiency may cause a problem in revegetating most of these soils. It is difficult to distinguish soil taxonomic families by using their respective chemical compositions. because of small between-family variability. Topsoil from a reclaimed area of the San Juan mine (area 3) most closely resembles the chemical composition of natural C horizons of soil from area 1. Spoil material that has not been topsoiled is likely to cause sodic-and saline-related problems in revegetation and may cause boron toxicity in plants. Topsoiling has apparently ameliorated these potential problems for plant growth on mine spoil. Total and extractable concentrations for elements and other parameters for each area of the San Juan Basin provide background information for the evaluation of the chemical quality of soils in each area.

  3. Dr. Robert Goddard

    NASA Image and Video Library

    2017-12-08

    Dr. Robert Goddard's rocket ready for flight. Roswell, New Mexico. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Join us on Facebook

  4. Ask Dr. Sue.

    ERIC Educational Resources Information Center

    Aronson, Susan S.

    1990-01-01

    Discusses the need for child care providers to be sure children in their care who are between the ages of 15 months and 5 years have had Haemophilus influenzae type b (Hib) vaccine. Urges child care center staff to avoid use of bean bag infant cushions and to inform parents about the hazards posed by the cushions. (DR)

  5. Incorporating Ecosystem Services into Community-level Decision-Making: A San Juan, Puerto Rico Case Study

    EPA Science Inventory

    EPA’s Office of Research and Development’s Sustainable and Healthy Communities Research Program is developing tools and approaches to incorporate ecosystem goods and services concepts into community-level decision-making. The San Juan Community Study is one of a serie...

  6. Dr. Shawn Mehlenbacher 2012 Wilder Silver Medal Recipient

    USDA-ARS?s Scientific Manuscript database

    Dr. Shawn Mehlenbacher, Oregon State University, was awarded the 2012 Wilder Medal by the American Pomological Society for his contributions to hazelnut genetics and cultivar development. Dr. Mehlenbacher took over the leadership of the Oregon State University hazelnut breeding program in 1986 aft...

  7. The ORAC-DR data reduction pipeline

    NASA Astrophysics Data System (ADS)

    Cavanagh, B.; Jenness, T.; Economou, F.; Currie, M. J.

    2008-03-01

    The ORAC-DR data reduction pipeline has been used by the Joint Astronomy Centre since 1998. Originally developed for an infrared spectrometer and a submillimetre bolometer array, it has since expanded to support twenty instruments from nine different telescopes. By using shared code and a common infrastructure, rapid development of an automated data reduction pipeline for nearly any astronomical data is possible. This paper discusses the infrastructure available to developers and estimates the development timescales expected to reduce data for new instruments using ORAC-DR.

  8. Pronounced Shear Velocity Asymmetry in the Mantle Across the Juan de Fuca Ridge and Curious Lack of Features at the Gorda Ridge

    NASA Astrophysics Data System (ADS)

    Bell, S. W.; Ruan, Y.; Forsyth, D. W.

    2015-12-01

    With new Rayleigh-wave tomography results, we have detected a clear and strong asymmetry in the shear velocity structure of the Juan de Fuca ridge. Concentrated in a relatively thin layer with a depth range of ~30-60km, there lies a region of very low shear velocity, with velocities ranging from ~3.8km/s to 4.0km/s. Such low velocities provide strong evidence for the presence of partial melt. This low-velocity region is highly asymmetric, extending much further west than east of the ridge. Especially at shallow depths of ~35 km, this low-velocity region is concentrated just west of the southern portion of the ridge. Peaking near the Axial Seamount, the youngest of the Cobb-Eickelberg Seamounts, it extends south to the region around the small Vance Seamounts just north of the junction with the Blanco Fracture Zone. The Juan de Fuca plate is relatively stationary in the hotspot reference frame, and the Juan de Fuca ridge migrates westward in the hotspot reference frame. Seamounts are overwhelmingly concentrated on the western flank of the ridge, and an asymmetric upwelling driven by migration in the hotspot reference frame has been proposed to explain the seamount asymmetry (i.e. Davis and Karsten, 1986). Our velocity asymmetry, which matches the seamount asymmetry, provides evidence for this asymmetric upwelling and its connection to migration in the absolute hotspot reference frame. In the shear velocity results, the Gorda ridge displays a remarkable lack of features, with no clearly identifiable expression in the subsurface velocity. There is evidence of a broad low-velocity feature beneath Gorda beginning at a depth of ~150 km, but no clear shallow features can be tied to the ridge. At the depths we can resolve (~25-250km), the anisotropy beneath and within the Juan de Fuca plate is small, indicating a deep source of the shear wave splitting results (Bodmer et al., in press), which indicate a fast axis aligned with the Juan de Fuca plate's absolute motion. Around

  9. Illegal drug use and its correlates in San Juan, Puerto Rico.

    PubMed

    Caetano, Raul; Vaeth, Patrice A C; Canino, Glorisa

    2018-04-01

    Data on the prevalence and correlates of illegal drug use in Puerto Rico are now almost 20 years old. This study sought to estimate the 12-month prevalence of illegal and non-prescribed medical drug use in San Juan, Puerto Rico and identify sociodemographic correlates of use. Data are from a random household sample of 1510 individuals, 18-64 years of age in San Juan, Puerto Rico. The 12-month prevalence of any illegal or non-prescribed drug use was 16.5%. Prevalence among men (20.7%) was higher than among women (12.9%; chi 2  = 16.308; df = 1; p < .01). Prevalence for specific drugs ranged from 11.2% for marijuana to 0.2% for methadone. of the multiple logistic regression analysis showed that male gender (OR = 1.67, 95CI = 1.21-2.3; p < .01), age 18-29 (OR = 2.39; 95CI = 1.35-4.23; p < .01), age 30-39 (OR = 1.93; 95CI = 1.01-3.69; p < .05), low (OR = 2.03; 95CI = 1.36-3.02; p < .001) and medium (OR = 1.50; 95CL = 1.01-2.23; p < .05) family cohesion/pride, and no religious preference (OR = 1.99; 95CI = 1.23-3.22; p < .01) increased the odds of drug use. Annual family income of $40,000-$60,000 (OR = 0.45; 95CI = 0.21-0.93; p < .05) and $60,001 and more (OR = 0.35; 95CI = 0.13-0.94; p > .05) were negatively associated with drug use compared to annual income up to $10,000. As in many other places in the U.S., drug use in San Juan, Puerto Rico is high, affecting about 1 in 6 adults in the population. The highest prevalence is for marijuana use, which cannot be medically prescribed and of which recreational use is illegal on the island. Copyright © 2018 Elsevier B.V. All rights reserved.

  10. Observatorio Astronómico Nacional, Colombia

    NASA Astrophysics Data System (ADS)

    Murdin, P.

    2000-11-01

    The Observatorio Astronómico Nacional (OAN) was founded by José Celestino Mutis in the framework of the `Expedicion Botanica' on 20 August 1803. His first astronomer was Francisco Jose de Caldas. By the turn of the century, Julio Garavito worked in celestial mechanics—a crater on the far side of the Moon bears his name....

  11. Dr. Robert Goddard

    NASA Image and Video Library

    2010-01-04

    Dr. Robert Goddard's rocket nose cone, parachute, and relase device, April 19, 1935. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Join us on Facebook

  12. Dr. Robert Goddard

    NASA Image and Video Library

    2010-01-04

    Dr. Robert Goddard with batteries and relay at the launch tower, May 19, 1937. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Join us on Facebook

  13. Dr. von Braun With German Rocket Experimenters

    NASA Technical Reports Server (NTRS)

    1930-01-01

    Dr. von Braun was among a famous group of rocket experimenters in Germany in the 1930s. This photograph is believed to be made on the occasion of Herman Oberth's Kegelduese liquid rocket engine being certified as to performance during firing. From left to right are R. Nebel, Dr. Ritter, Mr. Baermueller, Kurt Heinish, Herman Oberth, Klaus Riedel, Wernher von Braun, and an unidentified person.

  14. Gaia DR2 documentation Chapter 8: Astrophysical Parameters

    NASA Astrophysics Data System (ADS)

    Manteiga, M.; Andrae, R.; Fouesneau, M.; Creevey, O.; Ordenovic, C.; Mary, N.; Jean-Antoine-Piccolo, A.; Bailer-Jones, C. A. L.

    2018-04-01

    This chapter of the Gaia DR2 documentation describes Apsis, the Astrophysical Parameters Inference System used for processing Gaia DR2 data. Beyond this documentation, a complete description of the processing and the results, as well as additional validations, have been published in Andrae et al. (2018).

  15. Interview with Sanofi's Dr Tunde Falode.

    PubMed

    Falode, Tunde

    2017-01-01

    Dr Tunde Falode speaks to Elena Conroy, Commissioning Editor: Dr Tunde Falode is General Manager for the Diabetes and Cardiovascular Business Unit in the UK and Ireland at Sanofi, a global pharmaceutical company. Following graduation from the University of Jos Medical School in Nigeria, he secured a basic surgical training post through Guy's and St Thomas' hospitals in London, eventually specializing in cardiac and thoracic surgery, before changing his career path. In addition to his current role at Sanofi, he recently completed his specialist training in pharmaceutical medicine and has a keen interest in sports.

  16. ORAC-DR: Overview and General Introduction

    NASA Astrophysics Data System (ADS)

    Economou, Frossie; Jenness, Tim; Currie, Malcolm J.; Adamson, Andy; Allan, Alasdair; Cavanagh, Brad

    ORAC-DR is a general purpose automatic data reduction pipeline environment. It currently supports data reduction for the United Kingdom Infrared Telescope (UKIRT) instruments UFTI, IRCAM, UIST and CGS4, for the James Clerk Maxwell Telescope (JCMT) instrument SCUBA, for the William Herschel Telescope (WHT) instrument INGRID, for the European Southern Observatory (ESO) instrument ISAAC and for the Anglo-Australian Telescope (AAT) instrument IRIS-2. This document describes the general pipeline environment. For specific information on how to reduce the data for a particular instrument, please consult the appropriate ORAC-DR instrument guide.

  17. Dr. Tulp's Anatomy Lesson by Rembrandt: the third day hypothesis.

    PubMed

    Afek, Arnon; Friedman, Tal; Kugel, Chen; Barshack, Iris; Lurie, Doron J

    2009-07-01

    An autopsy was an important event in 17th century Holland. Autopsies were held in an 'anatomy theater' and performed according to a fixed protocol that often took up to 3 days to complete. Of the five group portraits painted by Rembrandt over the course of his career, two were anatomy lessons given by Dr. Tulp and Dr. Deyman. An examination of Rembrandt's painting Dr. Tulp's Anatomy Lesson (1632) and an X-ray image of the painting, as compared to other paintings of anatomy lessons from the same period, reveal interesting differences, such as positioning, and light and shadow. Not only was the autopsy not performed according to the usual protocol, but in this painting Rembrandt created a unique dramatic scene in his effort to tell a story. We suggest that Dr. Tulp and Rembrandt "modified" the painting of Dr. Tulp's anatomy lesson to emphasize Dr. Tulp's position as the greatest anatomist of his era--"Vesalius of Amsterdam," and as a way of demonstrating God's greatness by highlighting the hand as a symbol of the most glorious of God's creations.

  18. Physical, chemical, and biological data for detailed study of irrigation drainage in the San Juan River area, New Mexico, 1993-94, with supplemental data, 1991-95

    USGS Publications Warehouse

    Thomas, C.L.; Lusk, J.D.; Bristol, R.S.; Wilson, R.M.; Shineman, A.R.

    1997-01-01

    In response to increasing concern about the quality of irrigation drainage and its potential effects on fish, wildlife, and human health, the U.S. Department of the Interior formed an interbureau task group to prepare a plan for investigating water- quality problems on irrigation projects sponsored by the Department of the Interior. The San Juan River area in northwestern New Mexico was one of the areas designated for study. Investigators collected water, bottom-sediment, soil, and biological samples at more than 50 sites in the San Juan River area during 1993-94. Sample sites included (1) sites located within Department of the Interior irrigation project service areas, or areas that receive drainage from irrigation projects; (2) reference sites for comparison with irrigation project sites; and (3) sites located within the reach of the San Juan River from Navajo Dam to 10 miles downstream from the dam. The types of habitat sampled included the main stem of the San Juan River, backwater areas adjacent to the San Juan River, tributaries to the San Juan River, ponds, seeps, irrigation-delivery canals, irrigation-drainage canals, a stock tank, and shallow ground water. The types of media sampled included water, bottom sediment, soil, aquatic plants, aquatic invertebrates, amphibians, and fish. Semipermeable-membrane devices were used as a surrogate medium to sample both air and water in some instances. Sample measurements included concentrations of major ions, trace elements, organochlorine pesticides, polychlorinated biphenyls, polycyclic-aromatic-hydrocarbon compounds, and stable isotopes of hydrogen and oxygen. This report presents tables of physical, chemical, and biological data collected for the U.S. Department of the Interior National Irrigation Water-Quality Program. Additionally, supplemental physical, chemical, and biological data collected in association with the Navajo Indian Irrigation Project are presented.

  19. Tectonic Setting and Characteristics of Natural Fractures in MesaVerde and Dakota Reservoirs of the San Juan Basin

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    LORENZ,JOHN C.; COOPER,SCOTT P.

    2000-12-20

    The Cretaceous strata that fill the San Juan Basin of northwestern New Mexico and southwestern Colorado were shortened in a generally N-S to NN13-SSW direction during the Laramide orogeny. This shortening was the result of compression of the strata between southward indentation of the San Juan Uplift at the north edge of the basin and northward to northeastward indentation of the Zuni Uplift from the south. Right-lateral strike-slip motion was concentrated at the eastern and western basin margins of the basin to form the Hogback Monocline and the Nacimiento Uplift at the same time, and small amounts of shear maymore » have been pervasive within the basin as well. Vertical extension fractures, striking N-S to NNE-SSW with local variations (parallel to the Laramide maximum horizontal compressive stress), formed in both Mesaverde and Dakota sandstones under this system, and are found in outcrops and in the subsurface of the San Juan Basin. The immature Mesaverde sandstones typically contain relatively long, irregular, vertical extension fractures, whereas the quartzitic Dakota sandstones contain more numerous, shorter, sub-parallel, closely spaced, extension fractures. Conjugate shear planes in several orientations are also present locally in the Dakota strata.« less

  20. Declining Marbled Murrelet density, but not productivity, in the San Juan Islands, Washington, USA

    Treesearch

    Teresa J. Lorenz; Martin G. Raphael

    2018-01-01

    The Marbled Murrelet (Brachyramphus marmoratus) is federally threatened in part of its range in western North America. Information on density and productivity is important for managing populations. Over an 18-yr period, we monitored murrelet density and productivity ratios during the breeding season along 170 km of shoreline of the San Juan Islands...

  1. An HPLC method associated with a thermodynamic analysis to compare the binding of TRAIL and its nanovectorized form to death receptors DR4 and DR5 and their relationship to cytotoxicity.

    PubMed

    Guillaume, Yves Claude; Lethier, Lydie; André, Claire

    2016-11-15

    TRAIL is a member of the TNF family of cytokines which induces apoptosis of cancer cells via its binding to its cognate receptors, DR5 a high affinity site and DR4 a site of low affinity. Our working group has recently demonstrated that nanovectorization of TRAIL with single wall carbon nanotubes (abbreviated NPT) enhanced TRAIL affinity to the high affinity site DR5 and increased pro apoptotic potential in different human tumor cell lines. In this paper, the DR4 low affinity site was immobilized on a chromatographic support and the effect of temperature on a wide temperature range 1°C-50°C was studied to calculate the thermodynamic parameters of the binding of TRAIL and NPT to DR4 and DR5 receptors. For the first time the heat capacity changes for the different binding processes were determined. At a physiological pH (7.4) the heat capacity changes for the binding of NPT to DR4 and DR5 were respectively equal to -0.91kJ/molK and -0.28kJ/molK and those obtained for the binding of TRAIL to DR4 and DR5 were respectively equal to -1.54kJ/molK and -1.05kJ/molK. By the use of differential scanning calorimetry (DSC), a phase transition (∼12°C for DR5, ∼4°C for DR4) between a disordered (low temperature) and an ordered (high temperature) solid like state visualized in the receptor structure confirmed the temperature dependence of binding affinity enthalpy ΔH for soluble TRAIL and its nanovectorized form to its cognate receptors. In the low temperature domain, the positive ΔH values contribute non-favourably to the free energy of binding, TRAIL and NPT described similar affinities for DR4 and DR5. For the high temperature domain, negative ΔH values indicated that van der Waals interactions and hydrogen bonding are engaged favourably at the ligand - receptor interface. Above 30°C, their rank-ordered affinities were thus strongly different in the sequence: TRAIL DR4 DR4 DR5 < NPT DR5 . The nanovectorization of TRAIL enhanced its binding to both DR4

  2. 33 CFR 167.1300 - In the approaches to the Strait of Juan de Fuca: General.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY OFFSHORE TRAFFIC SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Pacific West Coast § 167.1300 In the approaches to the Strait of Juan de Fuca: General. The traffic separation scheme for the approaches to the...

  3. 33 CFR 167.1300 - In the approaches to the Strait of Juan de Fuca: General.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY OFFSHORE TRAFFIC SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Pacific West Coast § 167.1300 In the approaches to the Strait of Juan de Fuca: General. The traffic separation scheme for the approaches to the...

  4. 33 CFR 167.1300 - In the approaches to the Strait of Juan de Fuca: General.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY OFFSHORE TRAFFIC SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Pacific West Coast § 167.1300 In the approaches to the Strait of Juan de Fuca: General. The traffic separation scheme for the approaches to the...

  5. 33 CFR 167.1300 - In the approaches to the Strait of Juan de Fuca: General.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY OFFSHORE TRAFFIC SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Pacific West Coast § 167.1300 In the approaches to the Strait of Juan de Fuca: General. The traffic separation scheme for the approaches to the...

  6. Dr. von Braun with Seven Original Mercury Astronauts

    NASA Technical Reports Server (NTRS)

    1959-01-01

    In this photo, Dr. Wernher von Braun, Director of the U.S. Army Ballistic Missile Agency's (ABMA) Development Operations Division, is shown briefing the seven original Mercury astronauts in ABMA's Fabrication Laboratory. (Left to right) Guss Grissom, Walter Schirra, Alan Shepard, John Glenn, Scott Carpenter, Gordon Cooper, Donald Slayton, and Dr. von Braun.

  7. Marine Biodiversity in Juan Fernández and Desventuradas Islands, Chile: Global Endemism Hotspots

    PubMed Central

    Friedlander, Alan M.; Ballesteros, Enric; Caselle, Jennifer E.; Gaymer, Carlos F.; Palma, Alvaro T.; Petit, Ignacio; Varas, Eduardo; Muñoz Wilson, Alex; Sala, Enric

    2016-01-01

    The Juan Fernández and Desventuradas islands are among the few oceanic islands belonging to Chile. They possess a unique mix of tropical, subtropical, and temperate marine species, and although close to continental South America, elements of the biota have greater affinities with the central and south Pacific owing to the Humboldt Current, which creates a strong biogeographic barrier between these islands and the continent. The Juan Fernández Archipelago has ~700 people, with the major industry being the fishery for the endemic lobster, Jasus frontalis. The Desventuradas Islands are uninhabited except for a small Chilean military garrison on San Félix Island. We compared the marine biodiversity of these islands across multiple taxonomic groups. At San Ambrosio Island (SA), in Desventuradas, the laminarian kelp (Eisenia cokeri), which is limited to Desventuradas in Chile, accounted for >50% of the benthic cover at wave exposed areas, while more sheltered sites were dominated by sea urchin barrens. The benthos at Robinson Crusoe Island (RC), in the Juan Fernández Archipelago, comprised a diverse mix of macroalgae and invertebrates, a number of which are endemic to the region. The biomass of commercially targeted fishes was >2 times higher in remote sites around RC compared to sheltered locations closest to port, and overall biomass was 35% higher around SA compared to RC, likely reflecting fishing effects around RC. The number of endemic fish species was extremely high at both islands, with 87.5% of the species surveyed at RC and 72% at SA consisting of regional endemics. Remarkably, endemics accounted for 99% of the numerical abundance of fishes surveyed at RC and 96% at SA, which is the highest assemblage-level endemism known for any individual marine ecosystem on earth. Our results highlight the uniqueness and global significance of these biodiversity hotspots exposed to very different fishing pressures. PMID:26734732

  8. Marine Biodiversity in Juan Fernández and Desventuradas Islands, Chile: Global Endemism Hotspots.

    PubMed

    Friedlander, Alan M; Ballesteros, Enric; Caselle, Jennifer E; Gaymer, Carlos F; Palma, Alvaro T; Petit, Ignacio; Varas, Eduardo; Muñoz Wilson, Alex; Sala, Enric

    2016-01-01

    The Juan Fernández and Desventuradas islands are among the few oceanic islands belonging to Chile. They possess a unique mix of tropical, subtropical, and temperate marine species, and although close to continental South America, elements of the biota have greater affinities with the central and south Pacific owing to the Humboldt Current, which creates a strong biogeographic barrier between these islands and the continent. The Juan Fernández Archipelago has ~700 people, with the major industry being the fishery for the endemic lobster, Jasus frontalis. The Desventuradas Islands are uninhabited except for a small Chilean military garrison on San Félix Island. We compared the marine biodiversity of these islands across multiple taxonomic groups. At San Ambrosio Island (SA), in Desventuradas, the laminarian kelp (Eisenia cokeri), which is limited to Desventuradas in Chile, accounted for >50% of the benthic cover at wave exposed areas, while more sheltered sites were dominated by sea urchin barrens. The benthos at Robinson Crusoe Island (RC), in the Juan Fernández Archipelago, comprised a diverse mix of macroalgae and invertebrates, a number of which are endemic to the region. The biomass of commercially targeted fishes was >2 times higher in remote sites around RC compared to sheltered locations closest to port, and overall biomass was 35% higher around SA compared to RC, likely reflecting fishing effects around RC. The number of endemic fish species was extremely high at both islands, with 87.5% of the species surveyed at RC and 72% at SA consisting of regional endemics. Remarkably, endemics accounted for 99% of the numerical abundance of fishes surveyed at RC and 96% at SA, which is the highest assemblage-level endemism known for any individual marine ecosystem on earth. Our results highlight the uniqueness and global significance of these biodiversity hotspots exposed to very different fishing pressures.

  9. Climate Change Impacts on Hydrology and Water Management of the San Juan Basin

    NASA Astrophysics Data System (ADS)

    Rich, P. M.; Weintraub, L. H.; Chen, L.; Herr, J.

    2005-12-01

    Recent climatic events, including regional drought and increased storm severity, have accentuated concerns that climatic extremes may be increasing in frequency and intensity due to global climate change. As part of the ZeroNet Water-Energy Initiative, the San Juan Decision Support System includes a basin-scale modeling tool to evaluate effects of climate change on water budgets under different climate and management scenarios. The existing Watershed Analysis Risk Management Framework (WARMF) was enhanced with iterative modeling capabilities to enable construction of climate scenarios based on historical and projected data. We applied WARMF to 42,000 km2 (16,000 mi2) of the San Juan Basin (CO, NM) to assess impacts of extended drought and increased temperature on surface water balance. Simulations showed that drought and increased temperature impact water availability for all sectors (agriculture, energy, municipal, industry), and lead to increased frequency of critical shortages. Implementation of potential management alternatives such as "shortage sharing" or degraded water usage during critical years helps improve available water supply. In the face of growing concern over climate change, limited water resources, and competing demands, integrative modeling tools can enable better understanding of complex interconnected systems, and enable better decisions.

  10. National Biocontainment Training Center

    DTIC Science & Technology

    2012-08-01

    past reporting year, the training facility’s engineering and maintenance team welcomed trainees from the Institutio Nacional de Enfermedades Virales... Enfermedades Virales Humanas “Dr. Julio Maiztegui” and the Universidad Technologica Nacional attended the NBTC’s Biocontainment Engineering Training Program

  11. Overall properties of the Gaia DR1 reference frame

    NASA Astrophysics Data System (ADS)

    Liu, N.; Zhu, Z.; Liu, J.-C.; Ding, C.-Y.

    2017-03-01

    Aims: The first Gaia data release (Gaia DR1) provides 2191 ICRF2 sources with their positions in the auxiliary quasar solution and five astrometric parameters - positions, parallaxes, and proper motions - for stars in common between the Tycho-2 catalogue and Gaia in the joint Tycho-Gaia astrometric solution (TGAS). We aim to analyze the overall properties of Gaia DR1 reference frame. Methods: We compare quasar positions of the auxiliary quasar solution with ICRF2 sources using different samples and evaluate the influence on the Gaia DR1 reference frame owing to the Galactic aberration effect over the J2000.0-J2015.0 period. Then we estimate the global rotation between TGAS with Tycho-2 proper motion systems to investigate the property of the Gaia DR1 reference frame. Finally, the Galactic kinematics analysis using the K-M giant proper motions is performed to understand the property of Gaia DR1 reference frame. Results: The positional comparison between the auxiliary quasar solution and ICRF2 shows negligible orientation and validates the declination bias of -0.1mas in Gaia quasar positions with respect to ICRF2. Galactic aberration effect is thought to cause an offset 0.01mas of the Z axis direction of Gaia DR1 reference frame. The global rotation between TGAS and Tycho-2 proper motion systems, obtained by different samples, shows a much smaller value than the claimed value 0.24mas yr-1. For the Galactic kinematics analysis of the TGAS K-M giants, we find possible non-zero Galactic rotation components beyond the classical Oort constants: the rigid part ωYG = -0.38±0.15mas yr-1 and the differential part ω^primeYG = -0.29±0.19mas yr-1 around the YG axis of Galactic coordinates, which indicates possible residual rotation in Gaia DR1 reference frame or problems in the current Galactic kinematical model. Conclusions: The Gaia DR1 reference frame is well aligned to ICRF2, and the possible influence of the Galactic aberration effect should be taken into consideration

  12. Dr. Robert Goddard

    NASA Image and Video Library

    2010-01-04

    Dr. Robert Goddard's tower for "static" test near the shop at Roswell, New Mexico, 1930. The observation shelter (left foreground) is visible. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Join us on Facebook

  13. Dr. Robert Goddard

    NASA Image and Video Library

    2010-01-04

    Tail piece, with fixed movable air vanes, and vanes movable into the blast, of Dr. Robert Goddard's rocket, May 19, 1937. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Join us on Facebook

  14. Arsenic contamination of natural waters in San Juan and La Pampa, Argentina.

    PubMed

    O'Reilly, J; Watts, M J; Shaw, R A; Marcilla, A L; Ward, N I

    2010-12-01

    Arsenic (As) speciation in surface and groundwater from two provinces in Argentina (San Juan and La Pampa) was investigated using solid phase extraction (SPE) cartridge methodology with comparison to total arsenic concentrations. A third province, Río Negro, was used as a control to the study. Strong cation exchange (SCX) and strong anion exchange (SAX) cartridges were utilised in series for the separation and preservation of arsenite (As(III)), arsenate (As(V)), monomethylarsonic acid (MA(V)) and dimethylarsinic acid (DMA(V)). Samples were collected from a range of water outlets (rivers/streams, wells, untreated domestic taps, well water treatment works) to assess the relationship between total arsenic and arsenic species, water type and water parameters (pH, conductivity and total dissolved solids, TDS). Analysis of the waters for arsenic (total and species) was performed by inductively coupled plasma mass spectrometry (ICP-MS) in collision cell mode. Total arsenic concentrations in the surface and groundwater from Encon and the San José de Jáchal region of San Juan (north-west Argentina within the Cuyo region) ranged from 9 to 357 μg l(-1) As. Groundwater from Eduardo Castex (EC) and Ingeniero Luiggi (LU) in La Pampa (central Argentina within the Chaco-Pampean Plain) ranged from 3 to 1326 μg l(-1) As. The pH range for the provinces of San Juan (7.2-9.7) and La Pampa (7.0-9.9) are in agreement with other published literature. The highest total arsenic concentrations were found in La Pampa well waters (both rural farms and pre-treated urban sources), particularly where there was high pH (typically > 8.2), conductivity (>2,600 μS cm(-1)) and TDS (>1,400 mg l(-1)). Reverse osmosis (RO) treatment of well waters in La Pampa for domestic drinking water in EC and LU significantly reduced total arsenic concentrations from a range of 216-224 μg l(-1) As to 0.3-0.8 μg l(-1) As. Arsenic species for both provinces were predominantly As(III) and As(V). As

  15. Deglaciation and postglacial timberline in the San Juan Mountains, Colorado

    USGS Publications Warehouse

    Carrara, P.E.; Mode, W.N.; Rubin, M.; Robinson, S.W.

    1984-01-01

    Lake Emma, which no longer exists because of a mining accident, was a tarn in a south-facing cirque near the headwaters of the Animas River in the San Juan Mountains of southwestern Colorado. During the Pinedale glaciation, this area was covered by a large transection glacier centered over the Lake Emma region. Three radiocarbon dates on basal organic sediment from Lake Emma indicate that by ca. 15,000 yr B.P. this glacier, one of the largest in the southern Rocky Mountains, no longer existed. Twenty-two radiocarbon dates on Picea and Abies krummholz fragments in the Lake Emma deposits indicate that from ca. 9600 to 7800 yr B.P., from 6700 to 5600 yr B.P., and at 3100 yr B.P. the krummholz limit was at least 70 m higher than present. These data, in conjunction with Picea:Pinus pollen ratios from both the Lake Emma site and the Hurricane Basin site of J. T. Andrews, P. E. Carrara, F. B. King, and R. Struckenrath (1975, Quaternary Research 5, 173-197) suggest than from ca. 9600 to 3000 yr B.P. timberline in the San Juan Mountains was higher than present. Cooling apparently began ca. 3000 yr B.P. as indicated by decreases in both the percentage of Picea pollen and Picea:Pinus pollen ratios at the Hurricane Basin site (Andrews et al., 1975). Cooling is also suggested by the lack of Picea or Abies fragments younger than 3000 yr B.P. at either the Lake Emma or the Hurricane Basin site. ?? 1984.

  16. Dr. Robert H. Goddard and His Rocket

    NASA Technical Reports Server (NTRS)

    2004-01-01

    Goddard rocket with four rocket motors. This rocket attained an altitude of 200 feet in a flight, November 1936, at Roswell, New Mexico. From 1930 to 1941, Dr. Goddard made substantial progress in the development of progressively larger rockets which attained altitudes of 2400 meters, and refined his equipment for guidance and control, his techniques of welding, and his insulation, pumps, and other associated equipment. In many respects, Dr. Goddard laid the essential foundations of practical rocket technology

  17. Dr. Robert H. Goddard and His Rocket

    NASA Technical Reports Server (NTRS)

    1940-01-01

    Goddard rocket in launching tower at Roswell, New Mexico, March 21, 1940. Fuel was injected by pumps from the fueling platform at left. From 1930 to 1941, Dr. Goddard made substantial progress in the development of progressively larger rockets, which attained altitudes of 2400 meters, and refined his equipment for guidance and control, his techniques of welding, and his insulation, pumps, and other associated equipment. In many respects, Dr. Goddard laid the essential foundations of practical rocket technology

  18. Juan Ruiz De Alarcón: Impairment as Empowerment in Early Modern Spain

    ERIC Educational Resources Information Center

    Clark, Gloria Bodtorf

    2016-01-01

    Juan Ruiz de Alarcón, a seventeenth-century writer and native of New Spain, so excelled at the craft of writing "comedias" that he is recognized as one of the great writers of early modern Spain. In his personal life Ruiz de Alarcón struggled with a significant bodily impairment, a large hump on both his back and front, which made him…

  19. 75 FR 54377 - Cattle Point Road Relocation; Draft Environmental Impact Statement; San Juan Island National...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-07

    ... to coastal bluff erosion which threatens Cattle Point Road located in San Juan Island National... threatened by coastal erosion at the base of the slope traversed by the road. This road passes through the... unsafe in a few years-- life expectancy (relative to coastal erosion) is estimated at approximately 100...

  20. Should pediatric patients wait for HLA-DR-matched renal transplants?

    PubMed

    Gritsch, H A; Veale, J L; Leichtman, A B; Guidinger, M K; Magee, J C; McDonald, R A; Harmon, W E; Delmonico, F L; Ettenger, R B; Cecka, J M

    2008-10-01

    Graft survival rates from deceased donors aged 35 years or less among all primary pediatric kidney transplant recipients in the United States between 1996 and 2004 were retrospectively examined to determine the effect of HLA-DR mismatches on graft survival. Zero HLA-DR-mismatched kidneys had statistically comparable 5-year graft survival (71%), to 1-DR-mismatched kidneys (69%) and 2-DR-mismatched kidneys (71%). When compared to donors less than 35 years of age, the relative rate of allograft failure was 1.32 (p = 0.0326) for donor age greater than or equal to age 35. There was no statistical increase in the odds of developing a panel-reactive antibody (PRA) greater than 30% at the time of second waitlisting, based upon the degree of HLA-A, -B or -DR mismatch of the first transplant, nor was there a 'dose effect' when more HLA antigens were mismatched between the donor and recipient. Therefore, pediatric transplant programs should utilize the recently implemented Organ Procurement and Transplantation Network's (OPTN)allocation policy, which prioritizes pediatric recipients to receive kidneys from deceased donors less than 35 years of age, and should not turn down such kidney offers to wait for a better HLA-DR-matched kidney.

  1. Dr. David Sawyer, Mickey Mouse and Dr. David Brown attend a ceremony at Ronald McNair Middle School

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Dr. David Sawyer (left), Superintendent of the Brevard County School District, Mickey Mouse, and Dr. David Brown, a NASA astronaut, attend a tribute to NASA astronaut Ronald McNair held in the gymnasium of Ronald McNair Magnet School in Cocoa, Fla. During the tribute, Walt Disney World presented a portrait of McNair to the school, which had previously been renamed for the fallen astronaut. McNair was one of a crew of seven who lost their lives during an accident following launch of the Space Shuttle Challenger in January 1986.

  2. Dr. Robert Goddard

    NASA Image and Video Library

    2017-12-08

    1930--Dr. Robert Goddard built this 30 by 60 ft. workshop for rocket construction at the Mescalero Ranch, 3 miles northeast of Roswell, New Mexico. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Join us on Facebook

  3. Dr. Robert Goddard

    NASA Image and Video Library

    2017-12-08

    The family home and birthplace of Dr. Robert Goddard in Worcester, Mass. was called Maple Hill and situated at Gates Lane, now called Tollawanda Drive. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Join us on Facebook

  4. Dr. Wernher Von Braun near the mobile launcher.

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Dr. George Mueller, NASA associate administrator for manned space flight, and Dr. Wernher Von Braun (right), director of the Marshall Space Flight Center, are seen near the mobile launcher carrying a 363 foot tall Saturn V space launch vehicle as the rocket is rolled from the vehicle assembly building at KSC for its three mile trip to the launch pad.

  5. Analysis of Upper Air, Ground and Remote Sensing Data for the Atlas Field Campaign in San Juan, Puerto Rico

    NASA Technical Reports Server (NTRS)

    Gonzalez-Cruz, Jorge E.

    2005-01-01

    The general climate of the island of Puerto Rico is dominated by the easterly trade winds from the Atlantic Ocean, and during synoptically calm days by the topographic and local land surface characteristics [1]. The urban canopy of the metropolitan area of San Juan, capital city of the Island, may introduce a new microclimate that changes the characteristics of the low atmosphere and interacts with the other microclimates already present in the island. The primitive land cover and land use (LCLU) of the metropolitan area of San Juan was composed by broadleaf trees, moist soils, and very dense vegetation in general. The urban LCLU changes the balance for the mass, momentum and energy between the bottom boundary and the lower atmosphere, creating different climate conditions over urban and rural regions. Some of these differences are low relative humidity and high temperatures observed in urban areas when compared to rural areas. These in turn produces a convective circulation over the urban areas, a phenomenon compared to the sea and land breezes, commonly known as heat islands (UHI). Factors that contribute to the formation of the UHI are anthropogenic heat sources, aerosols from pollutants, fast water canalization due to the presence of buildings and streets, among others. The comparison between urban and rural climates is the most common approach to analyze the UHI. These contrasts are larger in clear and calm conditions and tend to disappear in cloudy and windy weather. The UHI was recognized in the early 1950 s as closed isotherms that separates the city from the general temperature field [2]. The impact of the urban LCLU in San Juan, Puerto Rico, was quantified calculating the difference between historical data sets for the air temperature over an identified urban area and a rural area dT(U-R). The analysis of the climatological data revealed that a UHI exists in the metropolitan area of San Juan, Puerto Rico. The data reveals a permanent urban heat island

  6. [Four stages in the history of the Centro Médico Nacional Siglo XXI of the IMSS].

    PubMed

    Fajardo-Ortiz, Guillermo

    2015-01-01

    This document presents four stages in the history of the Centro Médico Nacional Siglo XXI (Centro Médico Nacional XXI Century) of the Instituto Mexicano del Seguro Social. The first stage started at the end of the third decade of the twentieth century and ended in 1961, it corresponded to the conception, planning and construction of what was to be the Centro Médico del Distrito Federal (Centro Médico of the Distrito Federal) belonging to the Secretaría de Salubridad y Asistencia (Ministry of Health and Assistance). The second stage began when the Center was acquired by the Institute, then was known like Centro Médico Nacional (Centro Médico Nacional ), being put into full operation in 1963, more than twenty-two years later, in 1985, an earthquake virtually ended it, immediately began its reconstruction, finishing the second stage. In 1989 began the third stage, different and new buildings complemented or replaced the structures damaged or destroyed by the earthquake which formed the now Centro Médico Nacional Siglo XXI (Centro Médico Nacional XXI Century). In 2004 the fourth stage opened when the four hospitals of the Center were categorized like Unidades Médicas de Alta Especialidad (High Specialized Medical Units).

  7. [The examination of men's wits by Juan Huarte de San Juan, and the dawn of the neurobiology of intelligence in the Spanish renaissance].

    PubMed

    Martín-Araguz, A; Bustamante-Martínez, C

    The Spanish renaissance doctor Juan Huarte de San Juan (1529-1588) was the author of a unique and immortal work, The Examination of Men's Wits, the edition princeps of which was printed in Baeza in 1575. Since then it has been reprinted at least 80 times and translated into seven languages, which makes it the most influential Spanish contribution to medicine ever published. In this paper we review the unjustly little-known figure of Huarte as the founder of Neuropsychology, and we also analyse his works from a historical and neuroscientific point of view. Huarte's writings deal with the problem of the organic relations between the brain and understanding, and accept the possible influences exerted by temper on the will within the field of the Neurobiology of Intelligence. Thus, over four centuries ago Huarte became the founder of Differential or Physiological Psychology, Neuropsychology, Eugenics and Career Guidance. Huarte's work not only played a fundamental role in the history and development of the body of neuroscientific knowledge, but has also been a clear (although not always cited) influence on scientists, philosophers and men of letters such as Alarcón, Bacon, Cabanis, Cervantes (whose Don Quixote was inspired by him), Charron, Chomsky, Gall, Goethe, Hume, Kant, Kretchmer, Lessing, Lope de Vega, Montaigne, Montesquieu, Nietzsche, Quevedo, Rousseau, Schopenhauer, Thomasius, Tirso de Molina and Ziegler. In the middle of the 16th century, Huarte and his Examination of Men's Wits, together with the works of the naturalist philosophers Gómez Pereira (Antoniana Margarita, 1554) and Miguel Sabuco (New Philosophy, 1587), constituted the prestigious triumvirate of Spanish Renaissance scholars who, for the first time in history, contemplated the workings of the brain from a point of view that had more to do with science than the supernatural.

  8. DrImpute: imputing dropout events in single cell RNA sequencing data.

    PubMed

    Gong, Wuming; Kwak, Il-Youp; Pota, Pruthvi; Koyano-Nakagawa, Naoko; Garry, Daniel J

    2018-06-08

    The single cell RNA sequencing (scRNA-seq) technique begin a new era by allowing the observation of gene expression at the single cell level. However, there is also a large amount of technical and biological noise. Because of the low number of RNA transcriptomes and the stochastic nature of the gene expression pattern, there is a high chance of missing nonzero entries as zero, which are called dropout events. We develop DrImpute to impute dropout events in scRNA-seq data. We show that DrImpute has significantly better performance on the separation of the dropout zeros from true zeros than existing imputation algorithms. We also demonstrate that DrImpute can significantly improve the performance of existing tools for clustering, visualization and lineage reconstruction of nine published scRNA-seq datasets. DrImpute can serve as a very useful addition to the currently existing statistical tools for single cell RNA-seq analysis. DrImpute is implemented in R and is available at https://github.com/gongx030/DrImpute .

  9. Tiffany Diamonds and Classical Music as Influences on the Performance of "Don Juan in Hell".

    ERIC Educational Resources Information Center

    Johnson, Jim

    This paper analyzes Paul Gregory's 1951 production of "Don Juan in Hell," now considered to be a seminal work in the development of professional and educational readers theatre. The paper contends that the production, which presented a nondramatic work without the usual emphasis on design and spectacle, forced a reexamination of the role…

  10. Dr. Hugh L. Dryden - portrait

    NASA Technical Reports Server (NTRS)

    1959-01-01

    Dr. Hugh Latimer Dryden, had many titles after his name in his lifetime. In 1949 he became the director of the National Advisory Committee for Aeronautics (NACA). Dr. Dryden received many accolades and awards both during his life and after his death, but the greatest and most appropriate honor came on March 26, 1976, when NASA renamed the NASA Flight Research Center as the NASA Hugh L. Dryden Flight Research Center. At the dedication ceremony NASA Administrator James C. Fletcher stated: 'in 1924, when the fastest racing planes did well to fly at 280 m.p.h., Dryden was already probing the transonic range of . . . flight. Later in the 1920s, he sought to develop methods of accurately measuring . . . turbulence in wind tunnels. In 1938 he was the first American to deliver the Wright Brothers lecture. His 'Turbulence and the Boundary Layer' became a classic summary on the subject. It is most fitting that this Flight Research Center, with its unique and highly specialized capability for solving aerospace problems, should memorialize the genius of Hugh Dryden.' Dr. Dryden was initially an aerodynamicist with the National Bureau of Standards. He did important early work in high-speed aerodynamics. In 1947 he became the director of aeronautical research for the NACA (a predecessor of the National Aeronautics and Space Administration). Two years later, he became NACA's director, a position he held until 1958 when he became deputy administrator of NASA.

  11. Dr. von Braun With Five of the Original Astronauts

    NASA Technical Reports Server (NTRS)

    1959-01-01

    Five of the seven original astronauts are seen with Dr. von Braun inspecting the Mercury-Redstone hardware in the Fabrication Laboratory of Army Ballistic Missile Agency (ABMA) in 1959. Left to right: Astronauts Walter Schirra, Alan Shepard, John Glenn, Scott Carpenter, Gordon Cooper, and Dr. von Braun.

  12. The research contributions of Dr. Paul Van Deusen

    Treesearch

    Thomas B. Lynch; Francis A. Roesch; John Paul McTague; Jeffrey H. Gove; Gregory A. Reams; Aaron R. Weiskittel

    2015-01-01

    Dr. Paul Van Deusen’s recent passing concluded a rich 30+-year research career dedicated to development and implementation of quantitative methods for forestry and natural resources. Since the early part of his career as a biometrician with the USDA Forest Service Southern Research Station in the 1980s-1990s and continuing with his later employment at NCASI, Dr. Van...

  13. Early onset of diabetes in the proband is the major determinant of risk in HLA DR3-DQ2/DR4-DQ8 siblings.

    PubMed

    Gillespie, Kathleen M; Aitken, Rachel J; Wilson, Isabel; Williams, Alistair J K; Bingley, Polly J

    2014-03-01

    Islet autoimmunity is initiated in infancy, and primary prevention trials require children at high genetic risk to be identified before autoantibodies appear. To inform screening strategies, we evaluated risks of autoimmunity and diabetes associated with HLA DR3-DQ2/DR4-DQ8 in U.K. families. Extended HLA haplotypes were determined in 2,134 siblings from the Bart's-Oxford Study followed to a median age of 22 years. Risks of diabetes and islet autoimmunity (more than two antibodies) were estimated by survival analysis. Of 138 informative DR3-DQ2/DR4-DQ8 siblings, 63% shared both haplotypes with their diabetic proband, 29% shared one, and 8% shared neither. In HLA-identical DR3-DQ2/DR4-DQ8 siblings, the cumulative risk of diabetes by age 15 was 17% (vs. 6% in those sharing one haplotype or none; P = 0.095). Risk varied, however, with the age at the onset of diabetes in the proband; the cumulative risk of autoimmunity and/or diabetes by age 15 was 61% in siblings of probands diagnosed when younger than 10 years old compared with only 4.7% in those diagnosed after age 10 years (P < 0.001). The age of the proband at diagnosis, but not HLA haplotype sharing, was an independent determinant of sibling risk. This suggests that non-HLA genes or epigenetic/environmental factors that accelerate the progression of type 1 diabetes in the proband strongly affect risk in siblings.

  14. 600 kyr of Hydrothermal Activity on the Cleft Segment of the Juan de Fuca Ridge

    NASA Astrophysics Data System (ADS)

    Middleton, J. L.; Mukhopadhyay, S.; Langmuir, C. H.; Costa, K.; McManus, J. F.; Katz, R. F.; Huybers, P. J.; Winckler, G.; Li, Y.

    2017-12-01

    Pressure fluctuations caused by glacially driven variations in sea level may modulate magmatic and hydrothermal output at submarine volcanic centers, with falling sea level driving increased volcanic activity. In turn, glacially paced changes in submarine volcanism could induce globally synchronous variations in the delivery of bioavailable iron and CO2 from mid-ocean ridges and thus provide solid-Earth feedbacks into the climate system. While evaluation of submarine volcanic output on orbital-timescales is technically challenging, near-ridge sediment cores hosting hydrothermal plume precipitates provide continuous, spatially integrated, and datable records to investigate the long-term behavior of hydrothermal systems. We will present new sedimentary records of hydrothermal variability spanning the past 600 kyr on the Cleft Segment of the Juan de Fuca Ridge in the Northeast Pacific. As an intermediate spreading-rate ridge, the Juan de Fuca Ridge is hypothesized to be particularly sensitive to sea level forcing at the Milankovitch frequencies of Pleistocene glacial cycles. Thus, the new records can be used to examine the connection between sea level and hydrothermal activity over multiple glacial cycles. Hydrothermal input is determined from iron and copper, with a titanium-based correction for lithogenic contributions. Sedimentary fluxes are then constrained using excess thorium-230 and extraterrestrial helium-3 as constant flux proxies. Preliminary results indicate 10-fold changes in hydrothermal iron and copper fluxes over the past 600 kyr and suggest a quasiperiodic variability in hydrothermal deposition on 100 to 120 kyr cycles. Comparison of the Juan de Fuca record with model predictions for an intermediate spreading ridge forced by Pleistocene glacial cycles finds frequent coincidence between predicted positive anomalies in magmatic output and observed peaks in hydrothermal deposition. This work encourages the continued exploration of the relationship between

  15. Mediated Debate, Historical Framing, and Public Art: The Juan de Onate Controversy in El Paso

    ERIC Educational Resources Information Center

    Perez, Frank G.; Ortega, Carlos F.

    2008-01-01

    In 1988, the El Paso, Texas, city council accepted a proposal to build twelve statues of historically important individuals as part of a downtown revitalization initiative. Juan de Onate was selected as the centerpiece statue of the XII Travelers Memorial of the Southwest. The decision to honor the Spanish colonizer triggered a local controversy…

  16. Vikrant Sahasrabuddhe, MBBS, MPH, DrPH | Division of Cancer Prevention

    Cancer.gov

    Dr. Vikrant Sahasrabuddhe is Program Director in the Division of Cancer Prevention at the National Cancer Institute overseeing clinical trials focused on prevention of cervical cancer and other human papillomavirus (HPV)-related cancers. Dr. |

  17. Sub-Seafloor Carbon Dioxide Storage Potential on the Juan de Fuca Plate, Western North America

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jerry Fairley; Robert Podgorney

    2012-11-01

    The Juan de Fuca plate, off the western coast of North America, has been suggested as a site for geological sequestration of waste carbon dioxide because of its many attractive characteristics (high permeability, large storage capacity, reactive rock types). Here we model CO2 injection into fractured basalts comprising the upper several hundred meters of the sub-seafloor basalt reservoir, overlain with low-permeability sediments and a large saline water column, to examine the feasibility of this reservoir for CO2 storage. Our simulations indicate that the sub-seafloor basalts of the Juan de Fuca plate may be an excellent CO2 storage candidate, as multiplemore » trapping mechanisms (hydrodynamic, density inversions, and mineralization) act to keep the CO2 isolated from terrestrial environments. Questions remain about the lateral extent and connectivity of the high permeability basalts; however, the lack of wells or boreholes and thick sediment cover maximize storage potential while minimizing potential leakage pathways. Although promising, more study is needed to determine the economic viability of this option.« less

  18. 77 FR 61632 - Final Environmental Impact Statement for Cattle Point Road Relocation, San Juan Island National...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-10

    ... Impact Statement (Final EIS) for alternatives designed to respond to coastal bluff erosion that threatens... the southeastern tip of San Juan Island, is threatened by coastal erosion at the base of the slope... (relative to coastal erosion) of each of the three action alternatives is estimated at approximately 100...

  19. Hydrothermal Vents of Juan de Fuca Ridge

    NASA Astrophysics Data System (ADS)

    Stark, Joyce

    As a member of REVEL (Research and Education: Volcanoes, Exploration and Life), I had an opportunity to participant in a scientific research cruise focused on the active volcanoes along the Juan de Fuca Ridge, the submarine spreading center off the Washington- Oregon-Canada coast. REVEL was sponsored by the National Science Foundation, University of Washington, Pennsylvania State University and the American Museum of Natural History. We studied the geological, chemical and biological processes associated with active hydrothermal systems and my research focused on the biological communities of the sulfide structures. We worked on board the Woods Hole Oceanographic Institution Vessel, R/V Atlantis and the submersible ALVIN was used to sample the "Black Smokers". As a member of the scientific party, I participated in collection and sorting of biological specimens from the vent communities, attended lectures by scientists, contributed to the cruise log website, maintained a journal and developed my own research project. It was my responsibility to bring this cutting-edge research back to the classroom.

  20. Arc-parallel extension and fluid flow in an ancient accretionary wedge: The San Juan Islands, Washington

    USGS Publications Warehouse

    Schermer, Elizabeth R.; Gillaspy, J.R.; Lamb, R.

    2007-01-01

    Structural analysis of the Lopez Structural Complex, a major Late Cretaceous terrane-bounding fault zone in the San Juan thrust system, reveals a sequence of events that provides insight into accretionary wedge mechanics and regional tectonics. After formation of regional ductile flattening and shear-related fabrics, the area was crosscut by brittle structures including: (1) southwest-vergent thrusts, (2) extension veins and normal faults related to northwest-southeast extension, and (3) conjugate strike-slip structures that record northwest-southeast extension and northeast-southwest shortening. Aragonite-bearing veins are associated with thrust and normal faults, but only rarely with strike-slip faults. High-pressure, low-temperature (HP-LT) minerals constrain the conditions for brittle deformation to ???20 km and <250 ??C. The presence of similar structures elsewhere indicates that the brittle structural sequence is typical of the San Juan nappes. Sustained HP-LT conditions are possible only if structures formed in an accretionary prism during active subduction, which suggests that these brittle structures record internal wedge deformation at depth and early during uplift of the San Juan nappes. The structures are consistent with orogen-normal shortening and vertical thickening followed by vertical thinning and along-strike extension. The kinematic evolution may be related initially to changes in wedge strength, followed by response to overthickening of the wedge in an unbuttressed, obliquely convergent setting. The change in vein mineralogy indicates that exhumation occurred prior to the strike-slip event. The pressure and temperature conditions and spatial and temporal extent of small faults associated with fluid flow suggest a link between these structures and the silent earthquake process. ?? 2007 Geological Society of America.

  1. [The Bernardino Álvarez Farm Hospital and Farm School: antecedents to Instituto Nacional de Neurología y Neurocirugía].

    PubMed

    Rodríguez-de Romo, Ana Cecilia; Castañeda-López, Gabriela

    2013-01-01

    By 1960, México's Manicomio General (General Asylum) could no longer fulfill the functions for which it was created so implementation of the so-called Castañeda Operation began, an initiative designed to close down and relocate psychiatric patients to other institutions. At that time, Dr. Manuel Velasco-Suárez was in charge of the General Direction of Neurology, Mental Health and Rehabilitation, and planned to create the Institute of Neurology on a site he already possessed for its construction. The Asylum was a dependency of the aforementioned Direction and Velasco- Suárez decided that some patients at the Castañeda could be moved to the old hacienda house that stood on that terrain. Thus was born the Bernardino Álvarez Farm Hospital. A year later, in 1961, the Farm School for the Weak-Minded, also named Bernardino Álvarez was established there as well. This paper examines the history of these two institutions as antecedents to the Instituto Nacional de Neurología y Neurocirugía.

  2. Dr. Robert Goddard

    NASA Image and Video Library

    2017-12-08

    Dr. Robert Goddard's 22 foot rocket in it's launching tower, 1940, near Roswell, New Mexico. N.T. Ljungquist on the ground, A.W. Kisk working on rocket and C. Mansur at top of tower. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Join us on Facebook

  3. Correlation of coal beds in the Fruitland Formation as interpreted from geophysical logs, east-central San Juan County, New Mexico

    USGS Publications Warehouse

    Sandberg, Dorothy T.

    1986-01-01

    Correlation of coal beds in the Fruitland Formation (Upper Cretaceous) in the subsurface, from interpretation of geophysical logs, is an outgrowth of unpublished studies of deep coal on the Navajo Reservation by the author in the Toadlena 30 x 60 minute quadrangle, New Mexico, and by W. J. Mapel in the Farmington 30 x 60 minute quadrangle, New Mexico.  The lines of sections of this report extend eastward from the reservation into east-central San Juan County, which is in the western part of the San Juan Basin.  In this area, the rocks dip gently northeast toward the central part of the basin.  The thick coal is less than 1,500 feet beneath the surface.  Of the 53 logs in the sections, 48 are from oil- and gas-test holes, and 5 are from coal-test holes (see table 1).  Stratigraphic relations of the Upper Cretaceous Lewis Shale, Pictured Cliffs Sandstone, and Fruitland Formation, shown on the cross sections and briefly reviewed below, have been previously described for this or other parts of the San Juan Basin by Hayes and Zapp (1955), Beaumont (1971), Fassett and hinds (1971), O;Sullivan and other (1972), and Molenaar (1983), among others.

  4. Reflections on Don Juan and on the utility of the unhappy love affair.

    PubMed

    Bergel, Ernest

    2011-12-01

    Based on an unusual clinical experience of a teenage boy in child psychotherapy, two conclusions are proposed: (1) that the extremely unhappy, early love affairs that occur in most men's lives serve a valuable function in helping them separate from their mothers sufficiently to be able to realistically relate to appropriate marriage partners, and (2) that some Don Juans start new relationships in order to break them off, rather than the reverse.

  5. NLRP1 deficiency attenuates diabetic retinopathy (DR) in mice through suppressing inflammation response.

    PubMed

    Li, Yan; Liu, Chang; Wan, Xin-Shun; Li, Shao-Wei

    2018-06-22

    Diabetic retinopathy (DR) is the common cause of diabetic vascular complications. The NOD-like receptor (NLR) family, pyrin domain containing 1 (NLRP1), also known as NALP1, inflammasome is the first member of the NLR family to be discovered, playing an important role in inflammatory response. However, its effect on DR development has not been reported. In the study, the wild type (WT) and NLRP1 -/- mice were injected with streptozotocin (STZ) to induce DR. The results indicated that NLRP1 -/- significantly increased bodyweight reduction and decreased blood glucose levels induced by STZ. WT/DR mice exhibited higher levels of NLRP1 in retinas. NLRP1 -/- ameliorated retinal abnormalities in DR mice using H&E staining. In addition, attenuated avascular areas and neovascular tufts were also observed in NLRP1 -/- /DR mice. The levels of pro-inflammatory cytokines in serum and retinas were highly induced in WT/DR mice, whereas being markedly reduced by NLRP1 -/- . In addition, vascular endothelial growth factor (VEGF) and Iba1 expressions induced by STZ in serum or retinas were significantly down-regulated in NLRP1 -/- /DR mice. Consistently, NLRP1 -/- attenuated ASC and Caspase-1 expressions in retinas of DR mice. Compared to WT/DR group, NLRP1 -/- markedly decreased retina p-nuclear factor-κB (NF-κB), interleukin-1β (IL-1β) and IL-18 levels. And similar results were confirmed in vitro that suppressing NLRP1/ASC inflammasome ameliorated inflammatory response in fructose-treated retinal ganglion cells. The results above indicated that the modulation of NLRP1 inflammasome might be a promising strategy for DR therapy. Copyright © 2018. Published by Elsevier Inc.

  6. Contemporaneous trachyandesitic and calc-alkaline volcanism of the Huerto Andesite, San Juan Volcanic Field, Colorado, USA

    USGS Publications Warehouse

    Parat, F.; Dungan, M.A.; Lipman, P.W.

    2005-01-01

    Locally, voluminous andesitic volcanism both preceded and followed large eruptions of silicic ash-flow tuff from many calderas in the San Juan volcanic field. The most voluminous post-collapse lava suite of the central San Juan caldera cluster is the 28 Ma Huerto Andesite, a diverse assemblage erupted from at least 5-6 volcanic centres that were active around the southern margins of the La Garita caldera shortly after eruption of the Fish Canyon Tuff. These andesitic centres are inferred, in part, to represent eruptions of magma that ponded and differentiated within the crust below the La Garita caldera, thereby providing the thermal energy necessary for rejuvenation and remobilization of the Fish Canyon magma body. The multiple Huerto eruptive centres produced two magmatic series that differ in phenocryst mineralogy (hydrous vs anhydrous assemblages), whole-rock major and trace element chemistry and isotopic compositions. Hornblende-bearing lavas from three volcanic centres located close to the southeastern margin of the La Garita caldera (Eagle Mountain - Fourmile Creek, West Fork of the San Juan River, Table Mountain) define a high-K calc-alkaline series (57-65 wt % SiO2) that is oxidized, hydrous and sulphur rich. Trachyandesitic lavas from widely separated centres at Baldy Mountain-Red Lake (western margin), Sugarloaf Mountain (southern margin) and Ribbon Mesa (20 km east of the La Garita caldera) are mutually indistinguishable (55-61 wt % SiO2); they are characterized by higher and more variable concentrations of alkalis and many incompatible trace elements (e.g. Zr, Nb, heavy rare earth elements), and they contain anhydrous phenocryst assemblages (including olivine). These mildly alkaline magmas were less water rich and oxidized than the hornblende-bearing calc-alkaline suite. The same distinctions characterize the voluminous precaldera andesitic lavas of the Conejos Formation, indicating that these contrasting suites are long-term manifestations of San Juan

  7. Dry Juan de Fuca slab revealed by quantification of water entering Cascadia subduction zone

    NASA Astrophysics Data System (ADS)

    Canales, J. P.; Carbotte, S. M.; Nedimovic, M. R.; Carton, H. D.

    2017-12-01

    Water is carried by subducting slabs as a pore fluid and in structurally bound minerals, yet no comprehensive quantification of water content and how it is stored and distributed at depth within incoming plates exists for any segment of the global subduction system. Here we use controlled-source seismic data collected in 2012 as part of the Ridge-to-Trench seismic experiment to quantify the amount of pore and structurally bound water in the Juan de Fuca plate entering the Cascadia subduction zone. We use wide-angle OBS seismic data along a 400-km-long margin-parallel profile 10-15 km seaward from the Cascadia deformation front to obtain P-wave tomography models of the sediments, crust, and uppermost mantle, and effective medium theory combined with a stochastic description of crustal properties (e.g., temperature, alteration assemblages, porosity, pore aspect ratio), to analyze the pore fluid and structurally bound water reservoirs in the sediments, crust and lithospheric mantle, and their variations along the Cascadia margin. Our results demonstrate that the Juan de Fuca lower crust and mantle are much drier than at any other subducting plate, with most of the water stored in the sediments and upper crust. Previously documented, variable but limited bend faulting along the margin, which correlates with degree of plate locking, limits slab access to water, and a warm thermal structure resulting from a thick sediment cover and young plate age prevents significant serpentinization of the mantle. Our results have important implications for a number of subduction processes at Cascadia, such as: (1) the dryness of the lower crust and mantle indicates that fluids that facilitate episodic tremor and slip must be sourced from the subducted upper crust; (2) decompression rather than hydrous melting must dominate arc magmatism in northern-central Cascadia; and (3) dry subducted lower crust and mantle can explain the low levels of intermediate-depth seismicity in the Juan de

  8. VizieR Online Data Catalog: Gaia DR1 (Gaia Collaboration, 2016)

    NASA Astrophysics Data System (ADS)

    Gaia Collaboration

    2016-06-01

    Gaia DR1 is based on observations collected between 25 July 2014 and 16 September 2015. Gaia DR1 contains positions (RA,DE) and G magnitudes for all sources with acceptable formal standard errors on positions. Positions and individual uncertainties are computed using a generic prior and Bayes' rule (detailed description in "Gaia astrometry for stars with too few observations. A Bayesian approach", Michalik et al., 2015A&A...583A..68M). The five-parameter astrometric solution - positions, parallaxes, and proper motions - for stars in common between the Tycho-2 Catalogue and Gaia is contained in Gaia DR1. This part of Gaia DR1 is based on the Tycho-Gaia Astrometric Solution (paper with detailed description (Michalik et al., 2015A&A...574A.115M); paper describing theory and background (Michalik et al., 2014A&A...571A..85M); paper describing quasar extension (Michalik & Lindegren, 2016A&A...586A..26M)). At the beginning of the routine phase, for a period of 4 weeks, a special scanning mode repeatedly covering the ecliptic poles on every spin was executed for calibration purposes. Photometric data of selected RR Lyrae and Cepheid variable stars based on these high-cadence measurements are contained in Gaia DR1. Positions (RA,DE) and G magnitudes for 2152 ICRF quasars (F. Mignard et al., 2016, A&A, in press.). The Gaia Archive DR1 data is available at archives.esac.esa.int/gaia. Tgas and Gaia Sources can be downloaded as VOTables, FITS or CSV at http://cdn.gea.esac.esa.int/Gaia/ If you use public Gaia DR1 data in your paper, please take note of our guide on how to acknowledge and cite Gaia DR1: http://gaia.esac.esa.int/documentation/GDR1/Miscellaneous/\\ seccreditandcitationinstructions.html (9 data files).

  9. Dissolved Oxygen (DO) and Nutrients Analysis in the Río Piedras River, San Juan, Puerto Rico

    NASA Astrophysics Data System (ADS)

    Santiago, I.; Infante, G.

    2016-02-01

    The Río Piedras is the only River in the metropolitan area of Puerto Rico. This River was the first water supplier and is part of the ancient aqueduct, the first treatment plant of the San Juan urban area. Because of its cultural and historic importance the ancient aqueduct was cataloged as a National Treasure by the National Trust of History Preservation in 2014. Actually, is protected by Para La Naturaleza (before named in Spanish as the "Fideicomiso de Conservación de Puerto Rico"). The research objectives were to evaluate and measure the dissolved oxygen (DO), total phosphorus (TP) and the heavy metals (HM) concentrations of the River. Also, to examine if the DO, TP and HM (Cu, Fe, Pb, Mn, Al, and Zn) concentrations were in compliance with the Environmental Protection Agency (EPA) standards. Using DO bottles, water samples were collected on three points during six dates. DO concentrations were measured with the YSI Pro GBOD. TP concentrations were analyzed using the UV-Vis spectrophotometer "HACH" (DR 5000). Utilizing the ICP (Inductively Coupled Plasma) spectrophotometer emission technique and the EPA protocols HM concentrations were measured. Preliminary results show that the DO measurements were from 5.00 mg/L to 7.00 mg/L (p-value=0.282). HM concentrations findings were 0.456 (correlation coefficient=0.9997), 1.205 (correlation coefficient=0.9972) and 3.287 (correlation coefficient=0.9950) for Zn, Cu and Cr, respectively. We expected highest HM concentrations in our finals results due to the drought weather during each samples collection. Data analysis for DO, TP and HM concentrations will be presented. Finally, the results obtained and the project details will be explained during the poster presentation.

  10. 78 FR 75332 - Foreign-Trade Zone 61-San Juan, Puerto Rico Application for Subzone, Parapiezas Corporation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-11

    ... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [S-65-2013] Foreign-Trade Zone 61--San Juan, Puerto Rico Application for Subzone, Parapiezas Corporation Amendment of Application The Puerto Rico Trade & Export Company, grantee of FTZ 61, has amended its application requesting subzone status for the facility of Parapiezas Corporation (78 FR 28800...

  11. Dr. Jacob Cohen presents the H. Julian Allen award to Anthony Colaprete.

    NASA Image and Video Library

    2017-03-16

    Dr. Jacob Cohen Director Office of Chief Scientist with Dr. Anthony Colaprete recipient of the H. Julian Allen Award In recognition as co-author of the outstanding scientific paper entitled "Detection of Water in the LCROSS Ejecta Pluma." Shown here Dr. Jacob Cohen presents the H. Julian Allen award to Anthony Colaprete.

  12. 75 FR 75492 - Notice of Realty Action; Recreation and Public Purposes Act Classification, San Juan County, UT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-03

    ...-87677] Notice of Realty Action; Recreation and Public Purposes Act Classification, San Juan County, UT... Management (BLM) has examined and found suitable for classification for lease or conveyance to the Utah... regarding this proposed classification until January 18, 2011. ADDRESSES: Comments may be submitted to the...

  13. DR AVRAM JOZEF VINAVER (1862-1915) - PIONEER OF RADIOLOGY IN SERBIA.

    PubMed

    Babić, Rade Radomir; Stanković Babić, Gordana

    2015-01-01

    Dr Abraham Joseph Vinaver (1862-1915), a Jew from Poland, was a pioneer of radiology in Serbia. He graduated from the Faculty of Medicine in Warsaw (1887), but lived and worked in abac (the Kingdom of Serbia) since 1890. Dr Abraham Joseph Vinarev - Career Development. He procured the first X-ray machine and developed radiological service in Sabac five years after the discovery of X-rays. These were the beginnings of radiology in Serbia. He introduced the application of artesian wells. Dr Abraham Joseph Vinarev - a Participant at the First Congress of Serbian Physicians and Naturalists, Belgrade 1904. "The diagnostic importance of X-rays in lung disease, especially in initial tuberculosis" and "Five Years of Treatment by X-Ray Machines" were the first works in the field of radiology in Serbia by this author. Dr Abraham Joseph Vinaver - Reserve Medical Officer in the Serbian Army. During the Balkan Wars, he was a volunteer with the rank of major engaged in military corps and he participated in the First World War as well. He died of malaria in 1915 in Gevgelija. "Dr Avram Vinaver"- Stanislav Vinarev. His dedication to work during the typhus epidemics was put into verses of a poem by his son Stanislav Vinarev. Dr Avram Vinaver Joseph was a noble man with a great heart, who selflessly sacrificed himself for the Serbian people and Serbia. He gave his contribution to the development of health services in Serbia, both in peacetime and wartime conditions. Dr Abraham Joseph Vinaver laid the foundations for today's radiology in Serbia.

  14. Special issue dedicated in memory of Dr. Edward H. Ahrens, Jr.

    PubMed

    Ahrens, Edward H

    2002-01-01

    This special issue of the "Cardiovascular Drug Reviews" is dedicated in memory of Dr. Edward H. Ahrens, Jr., who died on Dec. 9th, 2000 at the Princeton Medical Center in New Jersey at the age of 85. Dr. Ahrens was the Director of the Lipid Metabolism Laboratory at the Rockefeller University. Dr. Alexander Scriabine conceived the idea for the issue at the special memorial symposium held at the Rockefeller University on Feb. 05, 2002 under the auspices of The New York Lipid and Vascular Biology Research Club. Dr. Ahrens was the first president of the club. He started this club with Drs. Howard Eder and DeWitt Goodman. Dr. Eder thought that it would be a fitting attribute to honor one of the founding fathers of the club by hosting a memorial symposium. I, as the President of the club for that academic year, had no hesitation in accepting the proposal. This year will be the 40th anniversary of the club and its continued success provides a glimpse of the fine legacy left behind by Dr. Ahrens. Dr. Ahrens also played a pivotal role in the establishment of the Journal of Lipid Research. This is the 43rd year of the journal and in this commemorative issue we are reproducing a review he wrote for the 25th anniversary of the journal. I was never personally acquainted with Dr. Ahrens. However, I am honored that I got this opportunity to pay tribute to a great scientist whose work has contributed immensely to the progress of lipid research. He was a person who touched many lives and still continues to do so. My involvement in the remembrance of Dr. Ahrens shows that science not only impacts your contemporaries but also generations that follow you. Scientific research is a journey where you can leave your trails behind and be remembered for your work long after your departure from this world. Dr. Ahrens contributed immensely to the understanding of cholesterol metabolism. In the early stages of his career he showed that phospholipids solubilize fat in the blood. Now we know

  15. Dr. Robert Goddard

    NASA Image and Video Library

    2010-01-04

    The Goddard Space Flight Center was named in honor of Dr. Robert Goddard, a pioneer in rocket development. Dr. Goddard received patents for a multi-stage rocket and liquid propellants in 1914 and published a paper describing how to reach extreme altitudes six years later. That paper, "A Method of Reaching Extreme Altitudes," detailed methods for raising weather-recording instruments higher than what could be achieved by balloons and explained the mathematical theories of rocket propulsion. The paper, which was published by the Smithsonian Institution, also discussed the possibility of a rocket reaching the moon-a position for which the press ridiculed Goddard. Yet several copies of the report found their way to Europe, and by1927, the German Rocket Society was established, and the German Army began its rocket program in 1931. Goddard, meanwhile, continued his work. By 1926, he had constructed and tested the first rocket using liquid fuel. Goddard's work largely anticipated in technical detail the later German V-2 missiles, including gyroscopic control, steering by means of vanes in the jet stream of the rocket motor, gimbal-steering, power-driven fuel pumps and other devices. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Join us on Facebook

  16. DR-induced escape of O and C from early Mars

    NASA Astrophysics Data System (ADS)

    Zhao, Jinjin; Tian, Feng; Ni, Yufang; Huang, Xiaomeng

    2017-03-01

    Energetic particles produced in Dissociative recombination (DR) reactions could escape planets with low gravity, such as Mars, if they could overcome collisions with the surrounding background gases. In this work, a 3-D Monte Carlo model is developed to study these photochemical escape processes on early Mars. Although the DR reaction rates of O2+, CO2+, and CO+ increase monotonically with solar soft X-ray and extreme ultraviolet (XUV) flux, the peak of the calculated DR-induced escape rates of O is near 3 × XUV, and the DR-induced escape rates of C increase with XUV until 10 × XUV. The non-monotonic behavior can be explained by the increased column densities of background species in high XUV conditions, which can deflect energetic particles through collisions more efficiently. At 20 × XUV, CO+ DR is the main source of escaping O and C, and the escape of secondary particles could contribute to 30∼40% and 10% of the total escape of O and C respectively. The time-integrated DR-induced escape of O and C is equivalent to 1 m of H2O and 20 mbar of CO2 escaping early Mars since 4.5 billion years ago. The accumulated CO2 loss is much lower than what's needed to explain the carbon isotopic ratios on Mars and much lower than the total CO2 needed to warm up early Mars. If more vigorous escape mechanisms were absent on early Mars, substantial inventories of volatiles have not been detected yet.

  17. Interview with Smithsonian NASM Spacesuit Curator Dr. Cathleen Lewis

    NASA Technical Reports Server (NTRS)

    Lewis, Cathleen; Wright, Rebecca

    2012-01-01

    Dr. Cathleen Lewis was interviewed by Rebecca Wright during the presentation of an "Interview with Smithsonian NASM Spacesuit Curator Dr. Cathleen Lewis" on May 14, 2012. Topics included the care, size, and history of the spacesuit collection at the Smithsonian and the recent move to the state-of-the-art permanent storage facility at the Udvar-Hazy facility in Virginia.

  18. Dr. von Braun Tries Out the Neutral Buoyancy Simulator (NBS)

    NASA Technical Reports Server (NTRS)

    1967-01-01

    Marshall Space Flight Center (MSFC) Director, Dr. von Braun, submerges after spending some time under water in the MSFC Neutral Buoyancy Simulator (NBS). Weighted to a neutrally buoyant condition, Dr. von Braun was able to perform tasks underwater which simulated weightless conditions found in space.

  19. Faulting and hydration of the Juan de Fuca plate system

    NASA Astrophysics Data System (ADS)

    Nedimović, Mladen R.; Bohnenstiehl, DelWayne R.; Carbotte, Suzanne M.; Pablo Canales, J.; Dziak, Robert P.

    2009-06-01

    Multichannel seismic observations provide the first direct images of crustal scale normal faults within the Juan de Fuca plate system and indicate that brittle deformation extends up to ~ 200 km seaward of the Cascadia trench. Within the sedimentary layering steeply dipping faults are identified by stratigraphic offsets, with maximum throws of 110 ± 10 m found near the trench. Fault throws diminish both upsection and seaward from the trench. Long-term throw rates are estimated to be 13 ± 2 mm/kyr. Faulted offsets within the sedimentary layering are typically linked to larger offset scarps in the basement topography, suggesting reactivation of the normal fault systems formed at the spreading center. Imaged reflections within the gabbroic igneous crust indicate swallowing fault dips at depth. These reflections require local alteration to produce an impedance contrast, indicating that the imaged fault structures provide pathways for fluid transport and hydration. As the depth extent of imaged faulting within this young and sediment insulated oceanic plate is primarily limited to approximately Moho depths, fault-controlled hydration appears to be largely restricted to crustal levels. If dehydration embrittlement is an important mechanism for triggering intermediate-depth earthquakes within the subducting slab, then the limited occurrence rate and magnitude of intraslab seismicity at the Cascadia margin may in part be explained by the limited amount of water imbedded into the uppermost oceanic mantle prior to subduction. The distribution of submarine earthquakes within the Juan de Fuca plate system indicates that propagator wake areas are likely to be more faulted and therefore more hydrated than other parts of this plate system. However, being largely restricted to crustal levels, this localized increase in hydration generally does not appear to have a measurable effect on the intraslab seismicity along most of the subducted propagator wakes at the Cascadia margin.

  20. Education

    DTIC Science & Technology

    2003-01-01

    Frank Sosa, Dept. of the Air Force Col Juan Urbano , Peruvian Army Dr. Francis A’Hearn, Faculty Prof. William Mayall, Faculty COL Mark McGuire...insufficient time to meet job requirements such as planning lessons to grading papers, to participating in mandatory training to phoning parents to...

  1. Extending ORAC-DR for Offline Processing of ESO, INGRID, and Classic Cam data

    NASA Astrophysics Data System (ADS)

    Currie, M. J.

    2004-07-01

    ORAC-DR--a flexible reduction pipeline---was originally developed by the Joint Astronomy Centre for real-time inspection of reduced data at its telescopes. Starlink is extending ORAC-DR to process at home institutions data from other observatories, notably ESO, whose instruments make no provision for ORAC-DR. I outline the problems encountered and solutions implemented or proposed to apply ORAC-DR to the infra-red instruments ISAAC, NACO, INGRID, and Classic~Cam.

  2. Writing Virtue and Indigenous Rights: Juan Bautista De Pomar and the "Relación de Texcoco"

    ERIC Educational Resources Information Center

    Espericueta, José

    2015-01-01

    In his "Relación de Texcoco," Juan Bautista de Pomar (c. 1535-90) takes a political and moral stance against Spanish colonialism in Texcoco and the entire viceroyalty of New Spain. Responding to the "Instrucción y memoria's" (1577) request for information about the history and cultural practices of local populations, Pomar…

  3. The Dominican Republic-Central American Free Trade Agreement (DR-CAFTA): Understanding the Reasons Why the Dominican Republic (DR) Joined the CAFTA Negotiations

    DTIC Science & Technology

    2009-06-01

    the major issues that the DR faced was how to protect itself from imported U.S. beverages that contained high fructose corn syrup . Many Dominican... corn syrup as a sweetener.204 This was a controversial move, which gained support in the DR Congress after many sugar producers demanded increased...protection from foreign imports. The producers claimed that the introduction of imported corn syrup sweetened beverages would cause an approximate

  4. Faunal composition and organic surface encrustations at hydrothermal vents on the southern Juan De Fuca Ridge

    NASA Astrophysics Data System (ADS)

    Tunnicliffe, Verena; Fontaine, A. R.

    1987-10-01

    Examination of a small collection of macroinvertebrates from three vents of the southern Juan de Fuca vent field reveals differences between the vents with respect to species composition, species habits, and microbial and metallic deposits on their surfaces. TWo apparently new vestimentiferan species were found, and for the first time the Juan de Fuca palm worm was observed to dwell on smokers. High acidity values recorded in this system may interfere with the process of shell calcification in an archaeogastropod snail. The surfaces of vestimentifer an tubes at two vents are heavily encrusted with microbial and metallic accumulations. Scanning electron microscope, transmission electron microscope, and energy dispersive X ray microanalysis observations show that iron-based crusts on orange tubes are built from accumulations of an Fe-rich particle of distinctive size and shape. Morphological evidence is presented for the microbial origin of Fe-rich particles. Zn-rich particles found on black tubes are not of microbial origin. We suggest that iron deposition on surfaces in the vent environment is initially biocatalytic but subsequent deposits may build by simple inorganic reactions.

  5. 77 FR 63289 - Foreign-Trade Zone 61-San Juan, PR, Application for Subzone, Coamo Property & Investments, LLC...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-16

    ... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [S-107-2012] Foreign-Trade Zone 61--San Juan, PR, Application for Subzone, Coamo Property & Investments, LLC, Coamo, PR An application has been submitted to the..., requesting special-purpose subzone status for the facility of Coamo Property & Investments, LLC, located in...

  6. DR-induced Hot Oxygen and Carbon Coronae of Early Mars

    NASA Astrophysics Data System (ADS)

    Zhao, J.; Chassefiere, E.; Tian, F.; Chaufray, J. Y.; Leblanc, F.

    2017-12-01

    The evolution of Martian atmosphere is a key aspect to understand the habitability of Mars in time. The distributions of neutral atoms above the exobase of ancient Mars (corona) is important for understanding the interactions between the corona and the solar wind, which could help improving our understanding of the evolution of Martian atmosphere. In this work, a 3-D Monte Carlo Model is built to simulate Martian corona in different period of Mars history based on thermosphere structure corresponding to 1, 3, 10, and 20 times present solar XUV conditions and dissociative recombination (DR) reaction profiles. DR reactions of O2+, CO2+, and CO+ are considered as the sources of primary O and C. Secondary O and C atoms, which are formed through collisions between primaries and background species. We will discuss the dependence of physical properties of Martian corona as functions of solar XUV flux and DR reactions. We will also discuss the potential importance of CO+ DR as a contributor to Martian corona.

  7. The Final Kepler Planet Candidate Catalog (DR25)

    NASA Astrophysics Data System (ADS)

    Coughlin, Jeffrey; Thompson, Susan E.; Kepler Team

    2017-06-01

    We present Kepler's final planet candidate catalog, which is based on the Q1--Q17 DR25 data release and was created to allow for accurate calculations of planetary occurrence rates. We discuss improvements made to our fully automated candidate vetting procedure, which yields specific categories of false positives and a disposition score value to indicate decision confidence. We present the use of light curve inversion and scrambling, in addition to our continued use of pixel-level transit injection, to produce artificial planet candidates and false positives. Since these simulated data sets were subjected to the same automated vetting procedure as the real data set, we are able to measure both the completeness and reliability of the catalog. The DR25 catalog, source code, and a multitude of completeness and reliability data products are available at the Exoplanet Archive (http://exoplanetarchive.ipac.caltech.edu). The DR25 light curves and pixel-level data are available at MAST (http://archive.stsci.edu/kepler).

  8. Dr. Israel Cuellar (1946-2008)

    ERIC Educational Resources Information Center

    Zamarripa, Manuel X.

    2009-01-01

    On September 7th, 2008, the mental health field lost a trailblazing researcher and clinician as he lost his battle with amyotrophic lateral sclerosis (ALS), commonly referred to as Lou Gehrig's disease. Dr. Israel Cuellar made significant contributions to the study of acculturation including its importance in delivering appropriate mental health…

  9. [History of Instituto Nacional de Salud Ocupacional del Peru].

    PubMed

    Cossio-Brazzan, Juan M

    2012-06-01

    In Peru, the industry's development has made economic improvements but at the same time, it has had a major impact on the health of the workers; for that reason, it was necessary to generate control mechanisms. So, in 1940 it was created the Departmento de Higiene Industrial, which in 1956 was changed to Instituto de Salud Ocupacional, but it was deactivated in 1994. However, in 2001 it reappeared into the Ministerio de Salud organizational structure with the name of Instituto de Salud Ocupacional "Alberto Hurtado Abadía". Actually, it is the Centro Nacional de Salud Ocupacional y Protección del Ambiente para la Salud (CENSOPAS), organ of the Instituto Nacional de Salud which continues working in synergy with other institutions and sectors, making research to protect the health of exposed persons (workers and community) to contamination and risks associated with economic activities.

  10. Water cycle and salinity dynamics in the mangrove forests of Europa and Juan de Nova Islands, southwest Indian Ocean.

    PubMed

    Lambs, Luc; Mangion, Perrine; Mougin, Eric; Fromard, François

    2016-01-30

    The functioning of mangrove forests found on small coralline islands is characterized by limited freshwater inputs. Here, we present data on the water cycling of such systems located on Europa and Juan de Nova Islands, Mozambique Channel. In order to better understand the water cycle and mangrove growth conditions, we have analysed the hydrological and salinity dynamics of the systems by gauge pressure and isotopic tracing (δ18O and δ2H values). Both islands have important seawater intrusion as measured by the water level change and the high salinities in the karstic ponds. Europa Island displays higher salinity stress, with its inner lagoon, but presents a pluri-specific mangrove species formation ranging from shrub to forest stands. No freshwater signal could be detected around the mangrove trees. On Juan de Nova Island, the presence of sand and detrital sediment allows the storage of some amount of rainfall to form a brackish groundwater. The mangrove surface area is very limited with only small mono-specific stands being present in karstic depression. On the drier Europa Island, the salinity of all the water points is equal to or higher than that of the seawater, and on Juan de Nova the groundwater salinity is lower (5 to 20 PSU). This preliminary study shows that the karstic pothole mangroves exist due to the sea connection through the fractured coral and the high tidal dynamics.

  11. Depth to the Juan De Fuca slab beneath the Cascadia subduction margin - a 3-D model for sorting earthquakes

    USGS Publications Warehouse

    McCrory, Patricia A.; Blair, J. Luke; Oppenheimer, David H.; Walter, Stephen R.

    2004-01-01

    We present an updated model of the Juan de Fuca slab beneath southern British Columbia, Washington, Oregon, and northern California, and use this model to separate earthquakes occurring above and below the slab surface. The model is based on depth contours previously published by Fluck and others (1997). Our model attempts to rectify a number of shortcomings in the original model and update it with new work. The most significant improvements include (1) a gridded slab surface in geo-referenced (ArcGIS) format, (2) continuation of the slab surface to its full northern and southern edges, (3) extension of the slab surface from 50-km depth down to 110-km beneath the Cascade arc volcanoes, and (4) revision of the slab shape based on new seismic-reflection and seismic-refraction studies. We have used this surface to sort earthquakes and present some general observations and interpretations of seismicity patterns revealed by our analysis. For example, deep earthquakes within the Juan de Fuca Plate beneath western Washington define a linear trend that may mark a tear within the subducting plate Also earthquakes associated with the northern stands of the San Andreas Fault abruptly terminate at the inferred southern boundary of the Juan de Fuca slab. In addition, we provide files of earthquakes above and below the slab surface and a 3-D animation or fly-through showing a shaded-relief map with plate boundaries, the slab surface, and hypocenters for use as a visualization tool.

  12. Dr. Johney Green Jr. - Associate Laboratory Director for Mechanical and

    Science.gov Websites

    Thermal Engineering Sciences | NREL Dr. Johney Green Jr. - Associate Laboratory Director for Mechanical and Thermal Engineering Sciences Dr. Johney Green Jr. - Associate Laboratory Director for Mechanical and Thermal Engineering Sciences A photo of Johney Green In his role, Johney Green oversees early

  13. A heat vulnerability index to improve urban public health management in San Juan, Puerto Rico.

    PubMed

    Méndez-Lázaro, Pablo; Muller-Karger, Frank E; Otis, Daniel; McCarthy, Matthew J; Rodríguez, Ernesto

    2018-05-01

    Increased frequency and length of high heat episodes are leading to more cardiovascular issues and asthmatic responses among the population of San Juan, the capital of the island of Puerto Rico, USA. An urban heat island effect, which leads to foci of higher temperatures in some urban areas, can raise heat-related mortality. The objective of this research is to map the risk of high temperature in particular locations by creating heat maps of the city of San Juan. The heat vulnerability index (HVI) maps were developed using images collected by satellite-based remote sensing combined with census data. Land surface temperature was assessed using images from the Thermal Infrared Sensor flown on Landsat 8. Social determinants (e.g., age, unemployment, education and social isolation, and health insurance coverage) were analyzed by census tract. The data were examined in the context of land cover maps generated using products from the Puerto Rico Terrestrial Gap Analysis Project (USDA Forest Service). All variables were set in order to transform the indicators expressed in different units into indices between 0 and 1, and the HVI was calculated as sum of score. The tract with highest index was considered to be the most vulnerable and the lowest to be the least vulnerable. Five vulnerability classes were mapped (very high, high, moderate, low, and very low). The hottest and the most vulnerable tracts corresponded to highly built areas, including the Luis Munoz International Airport, seaports, parking lots, and high-density residential areas. Several variables contributed to increased vulnerability, including higher rates of the population living alone, disabilities, advanced age, and lack of health insurance coverage. Coolest areas corresponded to vegetated landscapes and urban water bodies. The urban HVI map will be useful to health officers, emergency preparedness personnel, the National Weather Service, and San Juan residents, as it helps to prepare for and to mitigate

  14. A heat vulnerability index to improve urban public health management in San Juan, Puerto Rico

    NASA Astrophysics Data System (ADS)

    Méndez-Lázaro, Pablo; Muller-Karger, Frank E.; Otis, Daniel; McCarthy, Matthew J.; Rodríguez, Ernesto

    2018-05-01

    Increased frequency and length of high heat episodes are leading to more cardiovascular issues and asthmatic responses among the population of San Juan, the capital of the island of Puerto Rico, USA. An urban heat island effect, which leads to foci of higher temperatures in some urban areas, can raise heat-related mortality. The objective of this research is to map the risk of high temperature in particular locations by creating heat maps of the city of San Juan. The heat vulnerability index (HVI) maps were developed using images collected by satellite-based remote sensing combined with census data. Land surface temperature was assessed using images from the Thermal Infrared Sensor flown on Landsat 8. Social determinants (e.g., age, unemployment, education and social isolation, and health insurance coverage) were analyzed by census tract. The data were examined in the context of land cover maps generated using products from the Puerto Rico Terrestrial Gap Analysis Project (USDA Forest Service). All variables were set in order to transform the indicators expressed in different units into indices between 0 and 1, and the HVI was calculated as sum of score. The tract with highest index was considered to be the most vulnerable and the lowest to be the least vulnerable. Five vulnerability classes were mapped (very high, high, moderate, low, and very low). The hottest and the most vulnerable tracts corresponded to highly built areas, including the Luis Munoz International Airport, seaports, parking lots, and high-density residential areas. Several variables contributed to increased vulnerability, including higher rates of the population living alone, disabilities, advanced age, and lack of health insurance coverage. Coolest areas corresponded to vegetated landscapes and urban water bodies. The urban HVI map will be useful to health officers, emergency preparedness personnel, the National Weather Service, and San Juan residents, as it helps to prepare for and to mitigate

  15. A heat vulnerability index to improve urban public health management in San Juan, Puerto Rico

    NASA Astrophysics Data System (ADS)

    Méndez-Lázaro, Pablo; Muller-Karger, Frank E.; Otis, Daniel; McCarthy, Matthew J.; Rodríguez, Ernesto

    2017-02-01

    Increased frequency and length of high heat episodes are leading to more cardiovascular issues and asthmatic responses among the population of San Juan, the capital of the island of Puerto Rico, USA. An urban heat island effect, which leads to foci of higher temperatures in some urban areas, can raise heat-related mortality. The objective of this research is to map the risk of high temperature in particular locations by creating heat maps of the city of San Juan. The heat vulnerability index (HVI) maps were developed using images collected by satellite-based remote sensing combined with census data. Land surface temperature was assessed using images from the Thermal Infrared Sensor flown on Landsat 8. Social determinants (e.g., age, unemployment, education and social isolation, and health insurance coverage) were analyzed by census tract. The data were examined in the context of land cover maps generated using products from the Puerto Rico Terrestrial Gap Analysis Project (USDA Forest Service). All variables were set in order to transform the indicators expressed in different units into indices between 0 and 1, and the HVI was calculated as sum of score. The tract with highest index was considered to be the most vulnerable and the lowest to be the least vulnerable. Five vulnerability classes were mapped (very high, high, moderate, low, and very low). The hottest and the most vulnerable tracts corresponded to highly built areas, including the Luis Munoz International Airport, seaports, parking lots, and high-density residential areas. Several variables contributed to increased vulnerability, including higher rates of the population living alone, disabilities, advanced age, and lack of health insurance coverage. Coolest areas corresponded to vegetated landscapes and urban water bodies. The urban HVI map will be useful to health officers, emergency preparedness personnel, the National Weather Service, and San Juan residents, as it helps to prepare for and to mitigate

  16. Association of HLA-DR1 with the allergic response to the major mugwort pollen allergen: molecular background.

    PubMed

    Knapp, Bernhard; Fischer, Gottfried; Van Hemelen, Dries; Fae, Ingrid; Maillere, Bernard; Ebner, Christof; Schreiner, Wolfgang; Bohle, Barbara; Jahn-Schmid, Beatrice

    2012-08-08

    Mugwort pollen allergens represent the main cause of pollinosis in late summer. The major allergen, Art v 1, contains only one single immunodominant, solely HLA-DR-restricted T cell epitope (Art v 125-36). The frequency of HLA-DRB1*01 is highly increased in mugwort-allergic individuals and HLA-DR1 serves as restriction element for Art v 125-36. However, Art v 125-36 also binds to HLA-DR4 with high affinity and DR1-restricted Art v 125-36 -specific T cell receptors can be activated by HLA-DR4 molecules. To understand the predominance of HLA-DR1 in mugwort allergy in spite of the degeneracy in HLA/peptide-binding and TCR-recognition, we investigated the molecular background of Art v 125-36 /MHC/TCR interactions in the context of HLA-DR1 compared to -DR4. The majority of Art v 125-36 -specific T cell lines and clones from HLA-DR1 carrying, mugwort pollen-allergic donors reacted to synthetic and naturally processed Art v 1-peptides when presented by HLA-DR1 or HLA-DR4 expressing antigen presenting cells. However, at limiting peptide concentrations DR1 was more effective in T cell stimulation. In addition, the minimal epitope for 50% of Art v 125-36 -specific T cells was shorter for DR1 than for DR4. In vitro binding assays of Art v 125-36 mutant peptides to isolated DR1- and DR4-molecules indicated similar binding capacities and use of the same register. In silico simulation of Art v 125-36 binding to HLA-DR1 and -DR4 suggested similar binding of the central part of the peptide to either molecule, but a higher flexibility of the N- and C-terminal amino acids and detachment at the C-terminus in HLA-DR1. The predominance of HLA-DR1 in the response to Art v 125-36 may be explained by subtle conformation changes of the peptide bound to DR1 compared to DR4. Computer simulation supported our experimental data by demonstrating differences in peptide mobility within the HLA-DR complex that may influence TCR-binding. We suggest that the minor differences observed in vitro may

  17. Dr. von Braun Tries Out the Neutral Buoyancy Simulator (NBS)

    NASA Technical Reports Server (NTRS)

    1967-01-01

    Marshall Space Flight Center (MSFC) Director, Dr. von Braun, is shown leaving the suiting-up van wearing a pressure suit prepared for a tryout in the MSFC Neutral Buoyancy Simulator (NBS). Weighted to a neutrally buoyant condition, Dr. von Braun was able to perform tasks underwater which simulated weightless conditions found in space.

  18. Celebrating the Life and Legacy of Dr. John Hope Franklin

    ERIC Educational Resources Information Center

    Harris, Robert L., Jr.; Levering-Lewis, David; French, John D.; Wharton, Clifton R., Jr.

    2009-01-01

    Dr. John Hope Franklin chronicled the experiences of African-Americans like no one before him, forcing America to recognize Black history as American history. His contributions were innumerable and his impact was abiding. In celebration of his life and legacy, the authors profile the celebrated scholar and activist, Dr. John Hope Franklin.

  19. DR2 blocker thioridazine: A promising drug for ovarian cancer therapy

    PubMed Central

    Yong, Min; Yu, Tinghe; Tian, Si; Liu, Shuaibin; Xu, Jiao; Hu, Jianguo; Hu, Lina

    2017-01-01

    Dopamine receptor 2 (DR2) may be a biomarker for various types of cancer. Ovarian cancer cells overexpress DR2; therefore, blocking DR2 may be a novel treatment strategy for ovarian cancer. Thioridazine, a DR2 blocker, has antineoplastic activity in a variety of cancer cells. In view of the requirement for novel therapeutic agents in ovarian cancer, the present study aimed to determine the potential effects of thioridazine in vitro and in vivo. It was revealed that the DR2 blocker thioridazine induced cell death in a dose-dependent manner in ovarian cancer cells. Thioridazine treatment induced apoptosis and autophagy, which may be attributed to an increased level of reactive oxygen species and associated DNA damage. Additionally, the expression of various proteins increased with oxidative stress, including nuclear factor E2-related factor 2, which is a pivotal transcriptional factor involved in cellular responses to oxidative stress. Heme oxygenase 1, NAPDH quinone dehydrogenase 1 and hypoxia inducible factor-1α and phosphorylated (p)-protein kinase B expression was significantly decreased, and the expression level of p-extracellular signal-related kinases and p-P38 was increased. Using 3-methyl adenine to inhibit autophagy caused the rate of apoptosis to increase. Thioridazine inhibited the growth of SKOV3 xenografts in nude mice. The present study demonstrated that the DR2 blocker thioridazine exhibited anticancer effects in vitro and in vivo, suggesting that thioridazine may be used as a potential drug in ovarian cancer therapy. PMID:29344260

  20. Dr. Robert Goddard

    NASA Image and Video Library

    2010-01-04

    1930—Preparations are made to unreal remote control wires. The shelter in distance is 1,000 feet from Dr. Robert Goddard’s rocket launching tower, 10 miles northwest of Roswell, New Mexico. The shelter at left is 55 feet from the tower, and was used for static test only. It was later removed. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Join us on Facebook

  1. Culturally Responsive Instruction Leaves No Child Behind: The Story of Juan, a Pacific Island Special Needs Student

    ERIC Educational Resources Information Center

    Stoicovy, Catherine Eileen; Fee, Richard; Fee, Julie

    2012-01-01

    The purpose of this qualitative case study is to explore the use of retelling as a culturally responsive literacy strategy for Juan, a Pacific Island (Chamorro) special needs student on the island of Guam. Data were collected from the following sources: (1) participant-observation (2) fieldnotes (3) audiotaped recordings of students' oral…

  2. DR5 as a reporter system to study auxin response in Populus.

    PubMed

    Chen, Yiru; Yordanov, Yordan S; Ma, Cathleen; Strauss, Steven; Busov, Victor B

    2013-03-01

    KEY MESSAGE : Auxin responsive promoter DR5 reporter system is functional in Populus to monitor auxin response in tissues including leaves, roots, and stems. We described the behavior of the DR5::GUS reporter system in stably transformed Populus plants. We found several similarities with Arabidopsis, including sensitivity to native and synthetic auxins, rapid induction after treatment in a variety of tissues, and maximal responses in root tissues. There were also several important differences from Arabidopsis, including slower time to maximum response and lower induction amplitude. Young leaves and stem sections below the apex showed much higher DR5 activity than did older leaves and stems undergoing secondary growth. DR5 activity was highest in cortex, suggesting high levels of auxin concentration and/or sensitivity in this tissue. Our study shows that the DR5 reporter system is a sensitive and facile system for monitoring auxin responses and distribution at cellular resolution in poplar.

  3. Dr. John J. Stephens, Jr., metallurgist extraordinaire.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hosking, Floyd Michael

    The organizers of the Dr. John J. Stephens, Jr. Memorial Symposium: Deformation and Interfacial Phenomena in Advanced High-Temperature Materials are honoring the memory of Dr. Stephens and his many technical contributions that were accomplished over a relatively brief twenty year career. His research spanned the areas of creep and deformation of metals, dispersion-strengthened alloys and their properties, metal matrix composite materials, processing and properties of refractory metals, joining of ceramic-ceramic and metal-ceramic systems, active braze alloy development, and mechanical modeling of soldered and brazed assemblies. The purpose of this presentation is to highlight his research and engineering accomplishments, particularly duringmore » his professional career at Sandia National Laboratories in Albuquerque, NM.« less

  4. ORAC-DR: One Pipeline for Multiple Telescopes

    NASA Astrophysics Data System (ADS)

    Cavanagh, B.; Hirst, P.; Jenness, T.; Economou, F.; Currie, M. J.; Todd, S.; Ryder, S. D.

    ORAC-DR, a flexible and extensible data reduction pipeline, has been successfully used for real-time data reduction from UFTI and IRCAM (infrared cameras), CGS4 (near-infrared spectrometer), Michelle (mid-infrared imager and echelle spectrometer), at UKIRT; and SCUBA (sub-millimeter bolometer array) at JCMT. We have now added the infrared imaging spectrometers IRIS2 at the Anglo-Australian Telescope and UIST at UKIRT to the list of officially supported instruments. We also present initial integral field unit support for UIST, along with unofficial support for the imager and multi-object spectrograph GMOS at Gemini. This paper briefly describes features of the pipeline along with details of adopting ORAC-DR for other instruments on telescopes around the world.

  5. Dr. Ray Gause examines student Skylab experiment ED-52 Web Formation

    NASA Technical Reports Server (NTRS)

    1973-01-01

    Dr. Ray Gause of the NASA-Marshall Space Flight Center (MSFC) places dinner, in the form of a housefly, in the web of Arabella - the prime spider for the ED-52 Web Formation Experiment. Arabella can be delineated near the end of the black pen in Dr. Gause's hand. The experiment is one of 25 student experiments accepted for the Skylab program and will be performed during the Skylab 3 mission. Judy Miles, a 17-year-old high school student from Lexington, Massachusetts, is the student experimenter and Dr. Gause is the NASA student advisor.

  6. Gaia DR1 documentation Chapter 6: Variability

    NASA Astrophysics Data System (ADS)

    Eyer, L.; Rimoldini, L.; Guy, L.; Holl, B.; Clementini, G.; Cuypers, J.; Mowlavi, N.; Lecoeur-Taïbi, I.; De Ridder, J.; Charnas, J.; Nienartowicz, K.

    2017-12-01

    This chapter describes the photometric variability processing of the Gaia DR1 data. Coordination Unit 7 is responsible for the variability analysis of over a billion celestial sources. In particular the definition, design, development, validation and provision of a software package for the data processing of photometrically variable objects. Data Processing Centre Geneva (DPCG) responsibilities cover all issues related to the computational part of the CU7 analysis. These span: hardware provisioning, including selection, deployment and optimisation of suitable hardware, choosing and developing software architecture, defining data and scientific workflows as well as operational activities such as configuration management, data import, time series reconstruction, storage and processing handling, visualisation and data export. CU7/DPCG is also responsible for interaction with other DPCs and CUs, software and programming training for the CU7 members, scientific software quality control and management of software and data lifecycle. Details about the specific data treatment steps of the Gaia DR1 data products are found in Eyer et al. (2017) and are not repeated here. The variability content of the Gaia DR1 focusses on a subsample of Cepheids and RR Lyrae stars around the South ecliptic pole, showcasing the performance of the Gaia photometry with respect to variable objects.

  7. Hurricane recovery at Cabezas de San Juan, Puerto Rico, and research opportunities at Conservation Trust Reserves

    Treesearch

    Peter L. Weaver; Elizabeth Padilla Rodriguez

    2009-01-01

    The Cabezas de San Juan Natural Reserve (El Faro), an exposed peninsular area located in the Subtropical dry forest of northeastern Puerto Rico, was impacted by hurricanes Hugo (1989) and Georges (1998). From 1998 to 2008, a 0.10 ha plot was used to assess forest structure, species composition, and stem growth. During post-hurricane recovery, stem density, tree height...

  8. How Many Graduate? A Study of the Freshman Class of 1979 at San Juan High School. Revised.

    ERIC Educational Resources Information Center

    Gallant, Steve; Housden, Theresa

    The large number of dropouts estimated by the California State Department of Education has caused concern for educators, lawmakers, and the general public. A 1985 investigation of the graduation rate of the 1979 freshman class of San Juan High School was conducted which also sought to identify logistical problems with the collection of data needed…

  9. 78 FR 38359 - Approval of Record of Decision for Relocation of Cattle Point Road, San Juan Island National...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-26

    ... DEPARTMENT OF THE INTERIOR National Park Service [NPS-PWR-PWRO-12863; PPPWSAJHA0 PPMPSAS1Z.Y00000... Park, San Juan County, Washington AGENCY: National Park Service, Interior. ACTION: Notice of Record of....2), the Department of the Interior, National Park Service has prepared and approved a Record of...

  10. D&R Siding Co., LLC Information Sheet

    EPA Pesticide Factsheets

    D&R Siding Co., LLC (the Company) is located in Shelbyville, Tennessee. The settlement involves renovation activities conducted at a property constructed prior to 1978, located in Fayetteville, Tennessee.

  11. New perspectives on a 140-year legacy of mining and abandoned mine cleanup in the San Juan Mountains, Colorado

    USGS Publications Warehouse

    Yager, Douglas B.; Fey, David L.; Chapin, Thomas; Johnson, Raymond H.

    2016-01-01

    The Gold King mine water release that occurred on 5 August 2015 near the historical mining community of Silverton, Colorado, highlights the environmental legacy that abandoned mines have on the environment. During reclamation efforts, a breach of collapsed workings at the Gold King mine sent 3 million gallons of acidic and metal-rich mine water into the upper Animas River, a tributary to the Colorado River basin. The Gold King mine is located in the scenic, western San Juan Mountains, a region renowned for its volcano-tectonic and gold-silver-base metal mineralization history. Prior to mining, acidic drainage from hydrothermally altered areas was a major source of metals and acidity to streams, and it continues to be so. In addition to abandoned hard rock metal mines, uranium mine waste poses a long-term storage and immobilization challenge in this area. Uranium resources are mined in the Colorado Plateau, which borders the San Juan Mountains on the west. Uranium processing and repository sites along the Animas River near Durango, Colorado, are a prime example of how the legacy of mining must be managed for the health and well-being of future generations. The San Juan Mountains are part of a geoenvironmental nexus where geology, mining, agriculture, recreation, and community issues converge. This trip will explore the geology, mining, and mine cleanup history in which a community-driven, watershed-based stakeholder process is an integral part. Research tools and historical data useful for understanding complex watersheds impacted by natural sources of metals and acidity overprinted by mining will also be discussed.

  12. Application of techniques to identify coal-mine and power-generation effects on surface-water quality, San Juan River basin, New Mexico and Colorado

    USGS Publications Warehouse

    Goetz, C.L.; Abeyta, Cynthia G.; Thomas, E.V.

    1987-01-01

    Numerous analytical techniques were applied to determine water quality changes in the San Juan River basin upstream of Shiprock , New Mexico. Eight techniques were used to analyze hydrologic data such as: precipitation, water quality, and streamflow. The eight methods used are: (1) Piper diagram, (2) time-series plot, (3) frequency distribution, (4) box-and-whisker plot, (5) seasonal Kendall test, (6) Wilcoxon rank-sum test, (7) SEASRS procedure, and (8) analysis of flow adjusted, specific conductance data and smoothing. Post-1963 changes in dissolved solids concentration, dissolved potassium concentration, specific conductance, suspended sediment concentration, or suspended sediment load in the San Juan River downstream from the surface coal mines were examined to determine if coal mining was having an effect on the quality of surface water. None of the analytical methods used to analyzed the data showed any increase in dissolved solids concentration, dissolved potassium concentration, or specific conductance in the river downstream from the mines; some of the analytical methods used showed a decrease in dissolved solids concentration and specific conductance. Chaco River, an ephemeral stream tributary to the San Juan River, undergoes changes in water quality due to effluent from a power generation facility. The discharge in the Chaco River contributes about 1.9% of the average annual discharge at the downstream station, San Juan River at Shiprock, NM. The changes in water quality detected at the Chaco River station were not detected at the downstream Shiprock station. It was not possible, with the available data, to identify any effects of the surface coal mines on water quality that were separable from those of urbanization, agriculture, and other cultural and natural changes. In order to determine the specific causes of changes in water quality, it would be necessary to collect additional data at strategically located stations. (Author 's abstract)

  13. Dr. von Braun Tries Out the Neutral Buoyancy Simulator (NBS)

    NASA Technical Reports Server (NTRS)

    1967-01-01

    Astronaut L. Gordon Cooper checks the neck ring of a space suit worn by Marshall Space Flight Center (MSFC) Director, Dr. von Braun before he submerges into the water of the MSFC Neutral Buoyancy Simulator (NBS). Wearing a pressurized suit and weighted to a neutrally buoyant condition, Dr. von Braun was able to perform tasks underwater which simulated weightless conditions found in space.

  14. DR2DI: a powerful computational tool for predicting novel drug-disease associations

    NASA Astrophysics Data System (ADS)

    Lu, Lu; Yu, Hua

    2018-05-01

    Finding the new related candidate diseases for known drugs provides an effective method for fast-speed and low-risk drug development. However, experimental identification of drug-disease associations is expensive and time-consuming. This motivates the need for developing in silico computational methods that can infer true drug-disease pairs with high confidence. In this study, we presented a novel and powerful computational tool, DR2DI, for accurately uncovering the potential associations between drugs and diseases using high-dimensional and heterogeneous omics data as information sources. Based on a unified and extended similarity kernel framework, DR2DI inferred the unknown relationships between drugs and diseases using Regularized Kernel Classifier. Importantly, DR2DI employed a semi-supervised and global learning algorithm which can be applied to uncover the diseases (drugs) associated with known and novel drugs (diseases). In silico global validation experiments showed that DR2DI significantly outperforms recent two approaches for predicting drug-disease associations. Detailed case studies further demonstrated that the therapeutic indications and side effects of drugs predicted by DR2DI could be validated by existing database records and literature, suggesting that DR2DI can be served as a useful bioinformatic tool for identifying the potential drug-disease associations and guiding drug repositioning. Our software and comparison codes are freely available at https://github.com/huayu1111/DR2DI.

  15. DR2DI: a powerful computational tool for predicting novel drug-disease associations

    NASA Astrophysics Data System (ADS)

    Lu, Lu; Yu, Hua

    2018-04-01

    Finding the new related candidate diseases for known drugs provides an effective method for fast-speed and low-risk drug development. However, experimental identification of drug-disease associations is expensive and time-consuming. This motivates the need for developing in silico computational methods that can infer true drug-disease pairs with high confidence. In this study, we presented a novel and powerful computational tool, DR2DI, for accurately uncovering the potential associations between drugs and diseases using high-dimensional and heterogeneous omics data as information sources. Based on a unified and extended similarity kernel framework, DR2DI inferred the unknown relationships between drugs and diseases using Regularized Kernel Classifier. Importantly, DR2DI employed a semi-supervised and global learning algorithm which can be applied to uncover the diseases (drugs) associated with known and novel drugs (diseases). In silico global validation experiments showed that DR2DI significantly outperforms recent two approaches for predicting drug-disease associations. Detailed case studies further demonstrated that the therapeutic indications and side effects of drugs predicted by DR2DI could be validated by existing database records and literature, suggesting that DR2DI can be served as a useful bioinformatic tool for identifying the potential drug-disease associations and guiding drug repositioning. Our software and comparison codes are freely available at https://github.com/huayu1111/DR2DI.

  16. Plan of study for the regional aquifer-system analysis of the San Juan structural basin, New Mexico, Colorado, Arizona, and Utah

    USGS Publications Warehouse

    Welder, G.E.

    1986-01-01

    The San Juan structural basin is an 18,000 sq mi area that contains several extensive aquifers. The basin includes three surface drainage basins and parts of New Mexico, Colorado, Arizona, and Utah. Surface water in the area is fully appropriated, and the steadily increasing demand for groundwater has resulted in water supply concerns. Competition is great between mining and electric power companies, municipalities, and Indian communities for the limited groundwater supplies. This report outlines a 4-year plan for a study of the regional aquifer system in the San Juan structural basin. The purposes of the study are to define and understand the aquifer system; to assess the effects of groundwater use on the aquifers and streams; and to determine the availability and quality of groundwater in the basin. (Author 's abstract)

  17. The Child Development Training Consortium. A Status Report on the San Juan College AACJC-Kellogg Beacon College Project.

    ERIC Educational Resources Information Center

    Beers, C. David; Ott, Richard W.

    The Child Development Training Consortium, a Beacon College Project directed by San Juan College (SJC) is a collaborative effort of colleges and universities in New Mexico and Arizona. The consortium's major objective is to create child development training materials for community college faculty who teach "at-risk" Native American and…

  18. Sequence Stratigraphy of the Dakota Sandstone, Eastern San Juan Basin, New Mexico, and its Relationship to Reservoir Compartmentalization

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Varney, Peter J.

    2002-04-23

    This research established the Dakota-outcrop sequence stratigraphy in part of the eastern San Juan Basin, New Mexico, and relates reservoir quality lithologies in depositional sequences to structure and reservoir compartmentalization in the South Lindrith Field area. The result was a predictive tool that will help guide further exploration and development.

  19. A Geo-referenced 3D model of the Juan de Fuca Slab and associated seismicity

    USGS Publications Warehouse

    Blair, J.L.; McCrory, P.A.; Oppenheimer, D.H.; Waldhauser, F.

    2011-01-01

    We present a Geographic Information System (GIS) of a new 3-dimensional (3D) model of the subducted Juan de Fuca Plate beneath western North America and associated seismicity of the Cascadia subduction system. The geo-referenced 3D model was constructed from weighted control points that integrate depth information from hypocenter locations and regional seismic velocity studies. We used the 3D model to differentiate earthquakes that occur above the Juan de Fuca Plate surface from earthquakes that occur below the plate surface. This GIS project of the Cascadia subduction system supersedes the one previously published by McCrory and others (2006). Our new slab model updates the model with new constraints. The most significant updates to the model include: (1) weighted control points to incorporate spatial uncertainty, (2) an additional gridded slab surface based on the Generic Mapping Tools (GMT) Surface program which constructs surfaces based on splines in tension (see expanded description below), (3) double-differenced hypocenter locations in northern California to better constrain slab location there, and (4) revised slab shape based on new hypocenter profiles that incorporate routine depth uncertainties as well as data from new seismic-reflection and seismic-refraction studies. We also provide a 3D fly-through animation of the model for use as a visualization tool.

  20. Candidate members of the Pal 5, GD-1, Cetus Polar and Orphan tidal stellar halo streams from SDSS DR9, LAMOST DR3 and APOGEE catalogs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Li, Guang -Wei; Yanny, Brian; Zhang, Hao -Tong

    We present candidate members of the Pal 5, GD-1, Cetus Polar, and Orphan tidal stellar streams found in LAMOST DR3, SDSS DR9 and APOGEE catalogs. In LAMOST DR3, we find 20, 4, 24 high confidence candidates of tidal streams GD-1, Cetus Polar and Orphan respectively. We also list from the SDSS DR9 spectroscopic catalog 59, 118, 10 high confidence candidates of tidal streams Cetus Polar, Orphan and Pal 5, respectively. Furthermore, we find 7 high confidence candidates of the Pal 5 tidal stream in APOGEE data. Compared with SDSS, the new candidates from LAMOST DR3 are brighter, so that together, more of the color-magnitude diagram, including the giant branch can be explored. Analysis of SDSS data shows that there are 3 metallicity peaks of the Orphan stream and also shows some spatial separation. LAMOST data confirms multiple metallicities in this stream. The metallicity, given by the higher resolution APOGEE instrument, of the Pal 5 tidal stream is [Fe/H]more » $$\\sim -1.2$$, higher than that given earlier by SDSS spectra. Here, many previously unidentified stream members are tabulated here for the first time, along with existing members, allowing future researchers to further constrain the orbits of these objects as they move within the Galaxy's dark matter potential.« less

  1. Candidate members of the Pal 5, GD-1, Cetus Polar and Orphan tidal stellar halo streams from SDSS DR9, LAMOST DR3 and APOGEE catalogs

    DOE PAGES

    Li, Guang -Wei; Yanny, Brian; Zhang, Hao -Tong; ...

    2017-05-01

    We present candidate members of the Pal 5, GD-1, Cetus Polar, and Orphan tidal stellar streams found in LAMOST DR3, SDSS DR9 and APOGEE catalogs. In LAMOST DR3, we find 20, 4, 24 high confidence candidates of tidal streams GD-1, Cetus Polar and Orphan respectively. We also list from the SDSS DR9 spectroscopic catalog 59, 118, 10 high confidence candidates of tidal streams Cetus Polar, Orphan and Pal 5, respectively. Furthermore, we find 7 high confidence candidates of the Pal 5 tidal stream in APOGEE data. Compared with SDSS, the new candidates from LAMOST DR3 are brighter, so that together, more of the color-magnitude diagram, including the giant branch can be explored. Analysis of SDSS data shows that there are 3 metallicity peaks of the Orphan stream and also shows some spatial separation. LAMOST data confirms multiple metallicities in this stream. The metallicity, given by the higher resolution APOGEE instrument, of the Pal 5 tidal stream is [Fe/H]more » $$\\sim -1.2$$, higher than that given earlier by SDSS spectra. Here, many previously unidentified stream members are tabulated here for the first time, along with existing members, allowing future researchers to further constrain the orbits of these objects as they move within the Galaxy's dark matter potential.« less

  2. GENESI-DR - A single access point to Earth Science data

    NASA Astrophysics Data System (ADS)

    Cossu, R.; Goncalves, P.; Pacini, F.

    2009-04-01

    The amount of information being generated about our planet is increasing at an exponential rate, but it must be easily accessible in order to apply it to the global needs relating to the state of the Earth. Currently, information about the state of the Earth, relevant services, analysis results, applications and tools are accessible in a very scattered and uncoordinated way, often through individual initiatives from Earth Observation mission operators, scientific institutes dealing with ground measurements, service companies, data catalogues, etc. A dedicated infrastructure providing transparent access to all this will support Earth Science communities by allowing them to easily and quickly derive objective information and share knowledge based on all environmentally sensitive domains. The use of high-speed networks (GÉANT) and the experimentation of new technologies, like BitTorrent, will also contribute to better services for the Earth Science communities. GENESI-DR (Ground European Network for Earth Science Interoperations - Digital Repositories), an ESA-led, European Commission (EC)-funded two-year project, is taking the lead in providing reliable, easy, long-term access to Earth Science data via the Internet. This project will allow scientists from different Earth Science disciplines located across Europe to locate, access, combine and integrate historical and fresh Earth-related data from space, airborne and in-situ sensors archived in large distributed repositories. GENESI-DR builds a federated collection of heterogeneous digital Earth Science repositories to establish a dedicated infrastructure providing transparent access to all this and allowing Earth Science communities to easily and quickly derive objective information and share knowledge based on all environmentally sensitive domains. The federated digital repositories, seen as services and data providers, will share access to their resources (catalogue functions, data access, processing services etc

  3. Portrait of Dr. Von Braun with Walt Disney, 1954.

    NASA Technical Reports Server (NTRS)

    1954-01-01

    Marshall Center Director Dr. Wernher Von Braun is pictured with Walt Disney during a visit to the Marshall Space Flight Center in 1954. In the 1950s, Dr. Von Braun while working in California on the Saturn project, also worked with Disney studios as a technical director in making three films about Space Exploration for television. Disney's tour of Marshall in 1965 was Von Braun's hope for a renewed public interest in the future of the Space Program at NASA.

  4. Temporal Geochemistry Data from Five Springs in the Cement Creek Watershed, San Juan County, Colorado

    USGS Publications Warehouse

    Johnson, Raymond H.; Wirt, Laurie; Leib, Kenneth J.

    2008-01-01

    Temporal data from five springs in the Cement Creek watershed, San Juan County, Colorado provide seasonal geochemical data for further research in the formation of ferricretes. In addition, these data can be used to help understand the ground-water flow system. The resulting data demonstrate the difficulty in gathering reliable seasonal data from springs, show the unique geochemistry of each spring due to local geology, and provide seasonal trends in geochemistry for Tiger Iron Spring.

  5. HLA DR phenotypic frequencies and genetic risk of Type 1 diabetes in west region of Algeria, Tlemcen

    PubMed Central

    Aribi, Mourad; Moulessehoul, Soraya; Benabadji, Ahmed-Bakir; Kendoucitani, Mohammed

    2004-01-01

    Background The main genomic region controlling the predisposition to type 1 diabetes is the Human Leukocyte Antigens (HLA) class II of the major histocompatibility complex. Association with different HLA types depends also on the studied populations. In our investigation, we tried to measure the phenotypic HLA class II association frequencies of DR3 and/or DR4 antigens, using a serologic method called microlymphocytotoxicity analysis, in diabetic and nondiabetic (ND) subjects originating from the west-Algerian region of Tlemcen. The aim of the present study was to determine which HLA DR antigens represent a high susceptibility to develop the disease in this area. Using a case-control retrospective study design, we randomly recruited ninety-one related subjects, 39 type 1 diabetics and 52 ND as controls, at the Internal Medicine Board of Medical Centre University of Tlemcen. Results DR3 antigen frequencies were comparable between the type 1 diabetics and the ND subjects and showed no association with the disease (p = 1.000, OR = 0.95), whereas DR4 and DR3DR4 antigens were associated with susceptibility to develop type 1 diabetes (DR4; OR = 2.10, DR3DR4; OR = 1.30). Also, no incidence for DR3 (p = 0.2646) or DR3DR4 (p = 0.0699) antigen frequencies was related to the sex ratio. However, significant differences in HLA DR4 frequencies between type 1 diabetics and ND were found to be related to sex (p = 0.0085). Conclusion Taken together, our investigation showed that the strongest association with type 1 diabetes was noticed in the presence of HLA DR4 antigens followed by DR3DR4 antigens. This study highlighted a characteristic of Tlemcen population; a history of consanguineous marriages. Association studies between the disease and genetic polymorphisms should be undertaken in a population where consanguinity is more limited to reduce confounding in result interpretations. PMID:15331022

  6. Illustration of a fingerprinting method to isolate Gold King Release Metals from Background Concentrations in the San Juan River

    EPA Science Inventory

    Detecting the Gold King Mine metals as the release plume passed was difficult once it entered the San Juan River on August 8, 2015. Plume metals concentrations were relatively low after 200 km of travel and deposition in the Animas River while background concentrations of the sa...

  7. The American cranberry crowned jewel of the bog at the 2014 U.S.A. Science & Engineering Festival

    USDA-ARS?s Scientific Manuscript database

    For researchers in Dr. Juan Zalapa’s Cranberry Genetics and Genomics Lab, part of the USDA-ARS Vegetable Crops Research Unit, cranberries are more than a side dish on their Thanksgiving tables, they are the main course in their daily studies. The majority of these little red super-fruits come from t...

  8. Folk Media in Development.

    ERIC Educational Resources Information Center

    Instructional Technology Report, 1975

    1975-01-01

    This issue is dedicated to folk media. Using Indonesia for his case study, Dr. Nat Colletta analyzes traditional culture as a medium for development. Juan Diaz Bordenave expresses doubts about adapting folk media to development objectives; Susan Hostetler and Arthur Gillette report on uses of the theater to promote development objectives; and…

  9. Gaming Sea-based Multinational HA/DR Operations at PACOM Amphibious Leaders Symposium 2016

    DTIC Science & Technology

    2016-11-01

    DISTRIBUTION STATEMENT A. Approved for public release: distribution unlimited. Gaming Sea-based Multinational HA/DR Operations...Marine Corps photo by Cpl. Wesley Timm. Approved by: November 2016 Dr. E.D. McGrady Director, Integration and Gaming Advanced Technology and...TYPE Final2 3. DATES COVERED (From - To) 4. TITLE AND SUBTITLE Gaming Seabased Multinational HA/DR Operations at PACOM 5a. CONTRACT NUMBER N00014-16

  10. Dr. Sholom Wacholder - In their own words

    Cancer.gov

    Dr. Sholom Wacholder, a biostatistician in the NCI Division of Cancer Epidemiology and Genetics, discusses his role on a human papillomavirus vaccine clinical trial. From the archives of the NCI Cancer Bulletin - 2010.

  11. Insight into the wild origin, migration and domestication history of the fine flavour Nacional Theobroma cacao L. variety from Ecuador.

    PubMed

    Loor Solorzano, Rey Gaston; Fouet, Olivier; Lemainque, Arnaud; Pavek, Sylvana; Boccara, Michel; Argout, Xavier; Amores, Freddy; Courtois, Brigitte; Risterucci, Ange Marie; Lanaud, Claire

    2012-01-01

    Ecuador's economic history has been closely linked to Theobroma cacao L cultivation, and specifically to the native fine flavour Nacional cocoa variety. The original Nacional cocoa trees are presently in danger of extinction due to foreign germplasm introductions. In a previous work, a few non-introgressed Nacional types were identified as potential founders of the modern Ecuadorian cocoa population, but so far their origin could not be formally identified. In order to determine the putative centre of origin of Nacional and trace its domestication history, we used 80 simple sequence repeat (SSR) markers to analyse the relationships between these potential Nacional founders and 169 wild and cultivated cocoa accessions from South and Central America. The highest genetic similarity was observed between the Nacional pool and some wild genotypes from the southern Amazonian region of Ecuador, sampled along the Yacuambi, Nangaritza and Zamora rivers in Zamora Chinchipe province. This result was confirmed by a parentage analysis. Based on our results and on data about pre-Columbian civilization and Spanish colonization history of Ecuador, we determined, for the first time, the possible centre of origin and migration events of the Nacional variety from the Amazonian area until its arrival in the coastal provinces. As large unexplored forest areas still exist in the southern part of the Ecuadorian Amazonian region, our findings could provide clues as to where precious new genetic resources could be collected, and subsequently used to improve the flavour and disease resistance of modern Ecuadorian cocoa varieties.

  12. Maniac Talk - Dr. Eugenia Kalnay

    NASA Image and Video Library

    2015-03-31

    Eugenia Kalnay Maniac Lecture, March 31, 2015 Dr. Eugenia Kalnay, Distinguished University Professor and the first woman to get a doctorate in Meteorology from MIT, presented a Maniac Talk entitled, "Sheer luck: How I stumbled my way through a fantastic scientific career." Eugenia shared her life and times at the University of Buenos Aires, MIT, NASA, NOAA and University of Maryland, infused with dreams from her mother.

  13. Maniac Talk - Dr. Anne Thompson

    NASA Image and Video Library

    2014-04-30

    Anne Thompson Maniac Lecture, 30 April 2014 NASA climate scientist Dr. Anne Thompson presented a Maniac Talk entitled "A Career in Many Ozone Layers." Anne shared some of her long scientific career both as a researcher at Goddard and Meteorology professor at Penn State. She also described some of the problems she has worked on and tried to convey an enthusiasm for Earth Observations

  14. Maniac Talk - Dr. Anne Douglass

    NASA Image and Video Library

    2013-03-27

    Anne Douglass Maniac Lecture, 27 March, 2013 NASA climate scientist Dr. Anne Douglass presented a Maniac Talk entitled "Satellite Observations - the Touchstone of Atmospheric Modeling." Anne shared some of her scientific career that is filled with unexpected twists and turns and even a few blind alleys, but most important her passion in satellite measurements of ozone and other trace gases, which have been her touchstone.

  15. Maniac Talk - Dr. Brian Dennis

    NASA Image and Video Library

    2014-09-24

    Brian Dennis Maniac Lecture, September 24, 2014 NASA Solar Physicist Dr. Brian Dennis presented a Maniac Talk entitled "From Picking Potatoes to Measuring the Biggest Bangs in the Solar System -- Always a Farm Boy!" Brian described his formative years in England, then summarized our present understanding of how solar flares work and reviewed possible advances in instrumentation that could lead to major breakthroughs in the future.

  16. Maniac Talk - Dr. Jack Kaye

    NASA Image and Video Library

    2014-07-23

    Jack Kaye Maniac Lecture, July 23, 2014 Dr. Jack Kaye, Associate Director for Research at NASA Headquarters presented a Maniac Talk entitled, "An Unlikely but Rewarding Journey--From Quantum Chemistry to Earth Science Research Program Leadership." Jack took stock of his 30+ years at NASA, noting the people, opportunities, lessons learned, and choices that helped him get to where he is today and accomplish what he have.

  17. A portrait of the extreme solar system object 2012 DR30

    NASA Astrophysics Data System (ADS)

    Kiss, Cs.; Szabó, Gy.; Horner, J.; Conn, B. C.; Müller, T. G.; Vilenius, E.; Sárneczky, K.; Kiss, L. L.; Bannister, M.; Bayliss, D.; Pál, A.; Góbi, S.; Verebélyi, E.; Lellouch, E.; Santos-Sanz, P.; Ortiz, J. L.; Duffard, R.; Morales, N.

    2013-07-01

    2012 DR30 is a recently discovered solar system object on a unique orbit, with a high eccentricity of 0.9867, a perihelion distance of 14.54 AU, and a semi-major axis of 1109 AU, in this respect outscoring the vast majority of trans-Neptunian objects (TNOs). We performed Herschel/PACS and optical photometry to uncover the sizeand albedo of 2012 DR30, together with its thermal and surface properties. The body is 185 km in diameter and has a relatively low V-band geometric albedo of ~8%. Although the colours of the object indicate that 2012 DR30 is an RI taxonomy class TNO or Centaur, we detected an absorption feature in the Z-band that is uncommon among these bodies. A dynamical analysis of the target's orbit shows that 2012 DR30 moves on a relatively unstable orbit and was most likely only recently placed on its current orbit from the most distant and still highly unexplored regions of the solar system. If categorised on dynamical grounds 2012 DR30 is the largest Damocloid and/or high inclination Centaur observed so far. Herschel is an ESA space observatory with science instruments provided by European-led Principal Investigator consortia and with important participation from NASA.Appendices are available in electronic form at http://www.aanda.org

  18. New evidence for Oligocene to Recent slip along the San Juan fault, a terrane-bounding structure within the Cascadia forearc of southern British Columbia, Canada

    NASA Astrophysics Data System (ADS)

    Harrichhausen, N.; Morell, K. D.; Regalla, C.; Lynch, E. M.

    2017-12-01

    Active forearc deformation in the southern Cascadia subduction zone is partially accommodated by faults in the upper crust in both Washington state and Oregon, but until recently, these types of active forearc faults have not been documented in the northern part of the Cascadia forearc on Vancouver Island, British Columbia. Here we present new evidence for Quaternary slip on the San Juan fault that indicates that this terrane-bounding structure has been reactivated since its last documented slip in the Eocene. Field work targeted by newly acquired hi-resolution lidar topography reveals a deformed debris flow channel network developed within colluvium along the central portion of the San Juan fault, consistent with a surface-rupturing earthquake with 1-2 m of offset since deglaciation 13 ka. Near the western extent of the San Juan fault, marine sediments are in fault contact with mélange of the Pandora Peak Unit. These marine sediments are likely Oligocene or younger in age, given their similarity in facies and fossil assemblages to nearby outcrops of the Carmanah Group sediments, but new dating using strontium isotope stratigraphy will confirm this hypothesis. If these sediments are part of the Carmanah Group, they occur further east and at a higher elevation than previously documented. The presence of Oligocene or younger marine sediments, more than 400 meters above current sea level, requires a substantial amount of Neogene rock uplift that could have been accommodated by slip on the San Juan fault. A preliminary analysis of fault slickensides indicates a change in slip sense from left-lateral to normal along the strike of the fault. Until further mapping and analysis is completed, however, it remains unclear whether this kinematic change reflects spatial and/or temporal variability. These observations suggest that the San Juan fault is likely part of a network of active faults accommodating forearc strain on Vancouver Island. With the recent discovery of

  19. Gaia: Mapping the Milky Way: The Scientific Promise of Gaia DR2

    NASA Astrophysics Data System (ADS)

    Walton, Nicholas; ESA Gaia, Data Processing and Analysis Consortium (DPAC)

    2018-06-01

    The ESA Gaia mission will release its first major all sky astrometric catalogue (Gaia DR2), of more than 1.3 billion stars in our Galaxy, on 25 April 2018.This presentation will provide an overview of the Gaia mission, focussing on the significant scientific potential of the Gaia DR2 release. This is based on 22 months of input data and allows for a full Gaia stand alone astrometric solution, including parallaxes and proper motions, of over 1.3 billion sources. The astrometric uncertainties in Gaia DR2 will be at the level of tens of micro-arcsec for sources G<15.The Gaia DR2 release provides not only high precision full five parameter astrometry, but also a complete photometric catalogue of the sources on an all sky homogeneous photometric system in the Gaia G band and broad bands G_BP and G_RP. The release will include median radial velocities for more than six million stars (brighter that G_RVS = 12) together with a set of astrophysical parameters (including stellar temperatures) for some 150 million stars. Finally the Gaia DR2 release will include a set of additional data products including the light curves of more than half a million variable stars, and the positions of more than thirteen thousand objects in our Solar System.Together with the Gaia DR2 data products and associated release documentation, a small number of performance verification papers, using Gaia DR2 data only to provide new insights into a number of key areas of Gaia science, will be published in a special edition of A&A. These will provide demonstrations of the scientific potential of the Gaia DR2 catalogue, and also highlight some of the issues and limitations involved in the use of the Gaia DR2 data.The Gaia mission and Gaia Data Releases are made possible through the dedication and expertise of the community scientists and engineers involved in the design, construction, and operation of Gaia (led by ESA) and the collaboration of some 450 scientists and software engineers responsible for

  20. ORAC-DR -- integral field spectroscopy data reduction

    NASA Astrophysics Data System (ADS)

    Todd, Stephen

    ORAC-DR is a general-purpose automatic data-reduction pipeline environment. This document describes its use to reduce integral field unit (IFU) data collected at the United Kingdom Infrared Telescope (UKIRT) with the UIST instrument.

  1. Star Formation in the DR21 Region (B)

    NASA Technical Reports Server (NTRS)

    2004-01-01

    [figure removed for brevity, see original site] Annotated mosaic

    Hidden behind a shroud of dust in the constellation Cygnus is an exceptionally bright source of radio emission called DR21. Visible light images reveal no trace of what is happening in this region because of heavy dust obscuration. In fact, visible light is attenuated in DR21 by a factor of more than 10,000,000,000,000,000,000,000,000,000,000,000,000,000 (ten thousand trillion heptillion).

    New images from NASA's Spitzer Space Telescope allow us to peek behind the cosmic veil and pinpoint one of the most massive natal stars yet seen in our Milky Way galaxy. The never-before-seen star is 100,000 times as bright as the Sun. Also revealed for the first time is a powerful outflow of hot gas emanating from this star and bursting through a giant molecular cloud.

    The upper image is a large-scale mosaic assembled from individual photographs obtained with the InfraRed Array Camera (IRAC) aboard Spitzer. The image covers an area about two times that of a full moon. The mosaic is a composite of images obtained at mid-infrared wavelengths of 3.6 microns (blue), 4.5 microns (green), 5.8 microns (orange) and 8 microns (red). The brightest infrared cloud near the top center corresponds to DR21, which presumably contains a cluster of newly forming stars at a distance of 10,000 light-years.

    Protruding out from DR21 toward the bottom left of the image is a gaseous outflow (green), containing both carbon monoxide and molecular hydrogen. Data from the Spitzer spectrograph, which breaks light into its constituent individual wavelengths, indicate the presence of hot steam formed as the outflow heats the surrounding molecular gas. Outflows are physical signatures of processes that create supersonic beams, or jets, of gas. They are usually accompanied by discs of material around the new star, which likely contain the materials from which future planetary systems are formed. Additional newborn stars

  2. 77 FR 75145 - Foreign-Trade Zone 61-San Juan, Puerto Rico; Application for Subzone; Sea World, Inc.; Guaynabo, PR

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-19

    ... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [S-138-2012] Foreign-Trade Zone 61--San Juan, Puerto Rico; Application for Subzone; Sea World, Inc.; Guaynabo, PR An application has been submitted to..., requesting special-purpose subzone status for the facility of Sea World, Inc., located in Guaynabo, Puerto...

  3. Ridge asymmetry and deep aqueous alteration at the trench observed from Rayleigh wave tomography of the Juan de Fuca plate

    NASA Astrophysics Data System (ADS)

    Bell, Samuel; Ruan, Youyi; Forsyth, Donald W.

    2016-10-01

    Using Rayleigh wave tomography of noise-removed ocean bottom seismometer data from the Cascadia Initiative, we illuminate the structure of the upper mantle beneath the Juan de Fuca plate. Beneath the Juan de Fuca ridge, there is strong asymmetry, with a pronounced low-velocity zone in the 25-65 km depth range. Extending to the west from the spreading axis, this anomaly has velocities low enough to indicate the presence of melt. The asymmetry in velocity structure and the much greater abundance of seamounts on the west flank of the ridge suggest that dynamic, buoyant upwelling is important, perhaps triggered by thermal or compositional anomalies beneath Axial Seamount. In contrast, there is no evidence for asymmetry in the axial zone or lower than expected velocities beneath the Gorda ridge. On the eastern flank of the Juan de Fuca ridge, the shear velocity in the 25-65 depth range is higher than expected; the lithosphere appears to be colder and thicker than predicted by standard plate cooling models, perhaps caused by the downwelling counterpart of the upwelling on the west side of the ridge. Close to the trench, there is a sharp decrease in shear velocity. We interpret this as aqueous alteration caused by hydrothermal circulation through deep normal faults associated with bending of the plate. Beneath the Astoria and Nitinat fans, where abyssal plain sediment is thickest, the velocity decrease is much smaller, which is consistent with a thick sediment cap that prevents hydrothermal alteration of the plate.

  4. The life and contribution of Dr. Ronald Gitelman: a pioneer of modern chiropractic science.

    PubMed

    Vernon, Howard

    2013-03-01

    The life and contribution to chiropractic science of Dr. Ronald Gitelman is reviewed. Sources for this article included review of the notes prepared by Dr. Joseph Keating in his "biography" of the Canadian Memorial Chiropractic College (CMCC); review of the important articles published by Dr. Gitelman; review of the important projects undertaken by him along with various colleagues; notes from reminiscences obtained from many of these colleagues and discussions with his family. Dr. Gitelman's academic career spanned from 1963 to the late 1980's. During that time, he made foundational contributions to the development of chiropractic science including: developing the Archives (1974), the first collection of scientific articles supporting chiropractic science (which was subsequently published as the Chiropractic Archives Research Collection (CRAC)); delivering one of the few chiropractic papers at the seminal NINCDS conference (1975) and, developing the collaboration between CMCC and Dr. Kirkaldy-Willis at the University of Saskatoon (1976). He practiced in Toronto from 1961 to 2007. Dr. Gitelman was a pioneer in the development of chiropractic science. He died on October 7, 2012.

  5. Surface Hydrological Processes of Rock Glaciated Basins in the San Juan Mountains, Colorado

    NASA Astrophysics Data System (ADS)

    Mateo, E. I.

    2017-12-01

    Glaciers in the western United States have been examined in terms of their summer meltwater contributions to regional hydrological systems. In the San Juan Mountains of Colorado where glaciers do not and cannot exist due to a rising zero-degree isotherm, rock glaciers take the place of valley glaciers during the summer runoff period. Most of the rock glaciers in Colorado are located on a northerly slope aspect, however, there are multiple in the southwest region of the state that occur on different aspects. This study asked how slope aspect and rising air temperatures influenced the hydrological processes of streams below rock glaciers in the San Juan Mountains during the 2016 summer season. This project focused on three basins, Yankee Boy basin, Blue Lakes basin, and Mill Creek basin, which are adjacent to each other and share a common peak, Gilpin Peak. Findings of this one-season study showed that air temperature significantly influenced stream discharge below each rock glacier. Discharge and air temperature patterns indicate a possible air temperature threshold during late summer when rock glacier melt increased at a greater rate. The results also suggest that slope aspect of rock glacier basins influences stream discharge, but temperature and precipitation are likely larger components of the melt regimes. The continuation of data collection during the 2017 summer season has allowed for more detailed analysis of the relationship between air temperature and rock glacier melt. This continual expansion of the original dataset is crucial for understanding the hydrological processes of surface runoff below rock glaciers.

  6. Insight into the Wild Origin, Migration and Domestication History of the Fine Flavour Nacional Theobroma cacao L. Variety from Ecuador

    PubMed Central

    Loor Solorzano, Rey Gaston; Fouet, Olivier; Lemainque, Arnaud; Pavek, Sylvana; Boccara, Michel; Argout, Xavier; Amores, Freddy; Courtois, Brigitte; Risterucci, Ange Marie; Lanaud, Claire

    2012-01-01

    Ecuador’s economic history has been closely linked to Theobroma cacao L cultivation, and specifically to the native fine flavour Nacional cocoa variety. The original Nacional cocoa trees are presently in danger of extinction due to foreign germplasm introductions. In a previous work, a few non-introgressed Nacional types were identified as potential founders of the modern Ecuadorian cocoa population, but so far their origin could not be formally identified. In order to determine the putative centre of origin of Nacional and trace its domestication history, we used 80 simple sequence repeat (SSR) markers to analyse the relationships between these potential Nacional founders and 169 wild and cultivated cocoa accessions from South and Central America. The highest genetic similarity was observed between the Nacional pool and some wild genotypes from the southern Amazonian region of Ecuador, sampled along the Yacuambi, Nangaritza and Zamora rivers in Zamora Chinchipe province. This result was confirmed by a parentage analysis. Based on our results and on data about pre-Columbian civilization and Spanish colonization history of Ecuador, we determined, for the first time, the possible centre of origin and migration events of the Nacional variety from the Amazonian area until its arrival in the coastal provinces. As large unexplored forest areas still exist in the southern part of the Ecuadorian Amazonian region, our findings could provide clues as to where precious new genetic resources could be collected, and subsequently used to improve the flavour and disease resistance of modern Ecuadorian cocoa varieties. PMID:23144883

  7. Application of Virtual World Technologies to Undersea Warfare Learning

    DTIC Science & Technology

    2009-08-20

    Prescribed by ANSI Std Z39-18 Virtual World Technologies (VWTs) “Using Virtual Worlds To Shape the Future” by Dr. Susan U. Stucky, IBM Almaden Research...JUAN HSI US MIL ANDS AIR FORCE USS SKIPJACK11 Beavertail Lighthouse iTP TP ObsF ObsE Coordinated Military Presence NAVY AIR FORCE ARMYMARINES & OTHER

  8. Deglaciation and postglacial treeline fluctuation in the northern San Juan Mountains, Colorado

    USGS Publications Warehouse

    Carrara, Paul E.

    2011-01-01

    The San Juan Mountains of southwestern Colorado contain numerous lakes and bogs at and above treeline. In June 1978, Lake Emma, a tarn above present-day treeline, was suddenly drained by the collapse of underground mine workings. This study was initiated because the draining exposed a well-preserved archive of subfossil coniferous wood fragments that provided a unique opportunity to further our understanding of the paleoclimatic history of this region. These paleoclimatic studies-coniferous macrofossil identification in conjunction with radiocarbon dating, deuterium analysis of the dated conifer fragments, as well as pollen and fossil insect analyses-yielded new information regarding Holocene climate and accompanying treeline changes in the northern San Juan Mountains. This report synthesizes previously published reports by the author and other investigators, and unpublished information of the author bearing on late Pleistocene and Holocene treeline and climate in this region. Retreat of the glacier that occupied the upper Animas River valley from its Pinedale terminal position began about 19.4 + or - 1.5 10Be thousands of years ago and was essentially complete by about 12.3 + or - 1.0 10Be thousands of years ago. Two sets of late Pleistocene cirque moraines were identified in the northern San Juan Mountains. The older set is widespread and probably correlates with the Younger Dryas (11,000-10,000 radiocarbon years before present; 12,800-11,500 calendar years). The younger set is found only in the Grenadier Range and represents remnant glacier ice lying in well-shaded niches in a mountain range undergoing rapid deglaciation. A snowbank at the northern base of this range appears to be fronted by a Little Ice Age moraine. Soon after deglaciation the average July temperature is estimated to have been about 5°C cooler and timberline about 650 meters lower than at present. However, timberline (and treeline) responded rapidly to the postglacial warming and reached

  9. Maniac Talk - Dr. James Garvin

    NASA Image and Video Library

    2014-05-28

    James Garvin Maniac Lecture, 28 May 2014 Dr. James Garvin, Chief Scientist, NASA Goddard Space Flight Center, presented a Maniac Talk entitled "From Brownian Motion to Mars, by way of hockey on the rocks." Jim shared how his passion for rocks and landscapes drove him to promote new remote sensing approaches for measuring their topologies and led to founding of the Mars Science Laboratory and its Curiosity Rover.

  10. Death receptors DR6 and TROY regulate brain vascular development.

    PubMed

    Tam, Stephen J; Richmond, David L; Kaminker, Joshua S; Modrusan, Zora; Martin-McNulty, Baby; Cao, Tim C; Weimer, Robby M; Carano, Richard A D; van Bruggen, Nick; Watts, Ryan J

    2012-02-14

    Signaling events that regulate central nervous system (CNS) angiogenesis and blood-brain barrier (BBB) formation are only beginning to be elucidated. By evaluating the gene expression profile of mouse vasculature, we identified DR6/TNFRSF21 and TROY/TNFRSF19 as regulators of CNS-specific angiogenesis in both zebrafish and mice. Furthermore, these two death receptors interact both genetically and physically and are required for vascular endothelial growth factor (VEGF)-mediated JNK activation and subsequent human brain endothelial sprouting in vitro. Increasing beta-catenin levels in brain endothelium upregulate DR6 and TROY, indicating that these death receptors are downstream target genes of Wnt/beta-catenin signaling, which has been shown to be required for BBB development. These findings define a role for death receptors DR6 and TROY in CNS-specific vascular development. Copyright © 2012 Elsevier Inc. All rights reserved.

  11. [Sexuality education on the Internet : From Dr. Sommer to Dr. Google].

    PubMed

    Döring, Nicola

    2017-09-01

    Female and male adolescents in Germany are increasingly using the Internet to find information about sexuality and sexual health. This review paper summarizes what we know about the status quo of online sexuality education in Germany.Based on a systematic literature review including 40 papers from international, peer-reviewed journals spanning 2010-2017, this paper first describes different aspects of the sexuality-related online search behavior of adolescents: its prevalence, predictors, topics and contexts. One main finding is the fact that adolescents use a computer or smartphone to type their sexuality-related questions into the search engine Google or the search engine of the video platform YouTube.Based on 54 online searches, this paper subsequently presents the kind of sexuality-related online content adolescents find if they ask "Dr. Google" for sexual advice; a collection of 1236 authentic sexuality-related questions of adolescents was used for this analysis. It turned out that online sexuality education offered by leading professional organizations like the BZgA ("Bundeszentrale für gesundheitliche Aufklärung") or pro familia was nearly invisible, while numerous other providers of online sex education consistently appeared in the top Google search results. Among them were the "Dr. Sommer" team of the youth magazine Bravo; online healthcare and advice portals; online forums; the online encyclopedia Wikipedia and, above all, sex education channels on YouTube. In this paper, the latter are presented in more detail for the first time.The third part of the paper addresses the quality of online sexual education over four main areas of quality evaluation. The presentation of the status quo ends with some recommendations both for future research and for sexuality education in practice.

  12. Juan de Zumarraga; First Bishop of Mexico. The Tinker Pamphlet Series for the Teaching of Mexican American Heritage.

    ERIC Educational Resources Information Center

    Miller, Hubert J.

    The decades of the 1530's and 1540's witnessed the founding of Hispanic colonial institutions, many of which with modifications continue today. Among the most lasting of these has been the Church. This is part of Juan de Zumarraga's (Mexico's first archbishop) legacy, not only the setting up of ecclesiastical administration but also the prelate's…

  13. [Hospital San Juan de Dios: actor and victim of the public policies in Colombia].

    PubMed

    Pinilla, María Y; Abadía, César E

    2017-01-01

    In this article, we narrate and analyze the historical configuration that a group of female workers and a collective of social organizations made about the Hospital San Juan de Dios (HSJD) and Instituto Materno Infantil (IMI) in Bogotá, Colombia, within the neoliberal crisis in health. Our ethnographic research intersects the Latinamerican traditions of collaborative ethnography and historic anthropology. The research was conducted in two sites. In the first one, from 2005 until 2015, we had informal conversations and conducted workshops and semi-structured interviews with IMI workers. The second site corresponds to our participation in the deliberations of the Mesa Jurídica por el San Juan de Dios (2008-2009), which aimed to elevate a class action to defend the hospitals. We found that workers and social organizations made use of the colonial origin of the hospitals and their institutionalization as center of welfare policies in the country as a way to highlight their patrimonial, historical, educational and social importance. This historical construction critiques efforts that negate or transform the public character of the hospitals and helped them carry on different actions to denounce the neoliberal health care reform as the cause of the hospitals most important crisis and closing. The different actors denounce the change in the hospitals-state relationship, which transited from being central for the development of social policies to reflecting a symbolic and material elimination of the hospitals. Such transition benefits the market interests established by the neoliberal model.

  14. DR-nm23 expression affects neuroblastoma cell differentiation, integrin expression, and adhesion characteristics.

    PubMed

    Amendola, R; Martinez, R; Negroni, A; Venturelli, D; Tanno, B; Calabretta, B; Raschellà, G

    2001-01-01

    Nm23 gene family has been associated with metastasis suppression and differentiation. We studied DR-nm23 during neuroblastoma cells differentiation. DR-nm23 expression increased after retinoic acid induction of differentiation in human cell lines SK-N-SH and LAN-5. In several cell lines, overexpression of DR-nm23 was associated with more differentiated phenotypes. SK-N-SH cells increased vimentin expression, increased deposition of collagen type IV, modulated integrin expression, and underwent growth arrest; the murine neuroblastoma cell line N1E-115 showed neurite outgrowth and a striking enhancement of beta1 integrin expression. Up-regulation of beta1 integrin was specifically responsible for the increase in the adhesion to collagen type I-coated plates. Finally, cells overexpressing DR-nm23 were unable to growth in soft agar. In conclusion, DR-nm23 expression is directly involved in differentiation of neuroblastoma cells, and its ability to affects the adhesion to extracellular substrates and to inhibit growth in soft agar suggests an involvement in the metastatic potential of neuroblastoma.

  15. Collection of an adult gizzard shad (Dorosoma cepedianum) from the San Juan River, Utah

    USGS Publications Warehouse

    Mueller, G.A.; Brooks, J.L.

    2004-01-01

    We collected an adult gizzard shad (Dorosoma cepedianum) from the San Juan River just upstream of Lake Powell, Utah, on 6 June 2000. This represents the first documented occurrence of the species in the Colorado River or its tributaries. The adult male (35 cm TL, 470 g) was taken by trammel net from a small (0.5 ha), shallow (<2 m) backwater along with several other fish that included 3 endangered razorback sucker (Xyrauchen texanus). The specimen is stored at the Museum of Southwestern Biology, University of New Mexico, Albuquerque (curation number 49122).

  16. 75 FR 55347 - Notice of Realty Action: Competitive Sale of Public Land Near Aztec in San Juan County, NM

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-10

    ... city limits in San Juan County, New Mexico. The sale will be subject to the applicable provisions of... sealed bids equal to or greater than the appraised fair market value of the land. Bidders who submit..., Suite A, Farmington, New Mexico 87401. Sealed bids must also be submitted to this address. Supplemental...

  17. Spatial and Temporal Variability of Dust Deposition in the San Juan Mountains, CO: A Network of Late Holocene Lake Sediment Records

    NASA Astrophysics Data System (ADS)

    Arcusa, S.; Routson, C.; McKay, N.

    2017-12-01

    Millions of stakeholders living in the arid southwestern US rely on snowmelt from the San Juan Mountains of Colorado. However, dust deposition on snow accelerates snowmelt, challenging water management. Dustiness in the southwestern US is primarily mediated by drought, which is projected to increase in frequency and severity. Over the past several millennia, multidecadal-length megadroughts are hypothesized to have enhanced regional dustiness. These past megadroughts were more frequent during the Roman (ca. 1-400 CE) and Medieval (ca. 800-1300 CE) time periods and were similar in duration and severity to those projected for the future. Developing an understanding of the temporal and spatial patterns of past dust deposition in the San Juan Mountains will help inform adaptation strategies for future droughts. A network of short sediment cores from six alpine lakes in the San Juan Mountains were collected in 2016 and 2017 to investigate the spatial patterns of dust deposition. The range in lake basin characteristics in the network, such as catchment size, helps to constrain the influence of secondary dust deposition. Grain size analysis and X-ray Fluorescence were combined with radiocarbon dating to trace the temporal patterns in dust flux over the Late Holocene (the last 2000 years). The End-member Modelling Algorithm (EMMA) was used to estimate the dust proportion in the lake sediment, distinguishing from locally derived catchment material. Comparisons to modern dust-on-snow samples were made to identify the dust size distribution. The results show that deposition trends were not uniform between the south-eastern and north-western San Juans, with increasing trends towards the present in the former, possibly reflecting a shift in dust sources associated with changes in wind speed and direction. Dust levels greater than long term averages were recorded during the Medieval and Roman periods. The network also showed the influence of lake basin parameters, such as the

  18. Report on Follow-up Visit to Ecuador, Part 1

    DTIC Science & Technology

    1961-01-21

    Educacion Dr. Harold G. Conger, Director of the Servicio Cooperativo Interamericano de Salud Pdblica Mr, Milton Lobell, Director of the Servicio Cooperativo Interamericano de Agricultura Mr. David Luscombe, Chief of the Misicn Andina0 ...for Health; 3) Minister of Defense and his staff; 4) Planning Board (Junta de Planification y Coordination); 5) Director, National Institute of...Dr. Germanico Salgado, Technical Director of the Junta Nacional de Planificacidn y Coordinacidn Econolnica Dr. Luis Alberto Palacios, Dean of the

  19. Ambient Noise Tomography of the Northwestern U.S. and the Adjacent Juan de Fuca and Gorda Plates

    NASA Astrophysics Data System (ADS)

    Wang, H.; Feng, L.; Tian, Y.; Ritzwoller, M. H.

    2017-12-01

    The NSF Cascadia Initiative (CI) experiment includes 4-year deployments of ocean bottom seismometers (OBSs) on the Juan de Fuca and Gorda Plates. The CI experiment provides the unprecedented opportunity to investigate the crustal and upper mantle structure of this region. The 259 OBSs switched between Cascadia North in Years 1 and 3 and Cascadia South in Years 2 and 4 at around 160 different sites. Using the OBSs together with 89 stations near the Pacific coast, we estimate empirical Green's function (EGF) between station pairs by cross-correlating ambient noise recorded on their vertical components. Unlike continental stations, the OBSs are contaminated mainly by tilt and compliance noise at low frequencies (<0.1 Hz), which obscures the coherent ambient noise and makes it more difficult to retrieve reliable EGFs. Compliance noise comes from the seafloor deformation under gravity waves and its strength depends mostly on the pressure signal, thus compliance noise can be reduced significantly using the pressure record. Tilt noise is induced by currents near the seafloor, and the horizontal records are dominated by tilt noise at frequencies below 0.1 Hz. Tilt noise on the vertical components can be reduced using horizontal components. The "denoised" cross-correlations provide more reliable and higher signal to noise ratio (SNR) EGFs. Based on the estimated EGFs from the "denoised" vertical records, we use frequency-time analysis (FTAN) to retrieve the dispersion curve of Rayleigh waves between station pairs. Using the Rayleigh wave dispersion curves, we perform seismic tomography to construct isotropic and azimuthally anisotropic phase velocity maps at periods from about 8 to 30s across the Juan de Fuca and Gorda plates, extending up onto the continent. Previous studies have shown that the fast axis directions of 2ψ azimuthal anisotropy align parallel to present-day plate motion directions at longer periods and parallel to paleospreading directions at shorter periods

  20. Maniac Talk - Dr. William Lau

    NASA Image and Video Library

    2014-01-24

    William Lau Maniac Lecture, 24 January, 2014 Dr. William Lau, Deputy Director for Atmospheres, Earth Science Division at NASA Goddard, presented a Maniac Talk entitled "My Story: A Tale of Three Continents." Bill shared his early childhood under a colonial education system with strong Chinese cultural influence and how world events, cultural and education system of three major continents, Europe, Asia and North America shaped his upbringing career goals and work ethics.

  1. Modeling Dr. Dynasaur 2.0 Coverage and Finance Proposals

    PubMed Central

    Dick, Andrew W.; Price, Carter C.; Woods, Dulani; Freund, Deborah Anne; McNamara, Martin; Schramm, Steven P.; Berkman, Elrycc; Dehner, Tom

    2017-01-01

    Abstract The authors assessed an expansion of Vermont's Dr. Dynasaur program that would cover all residents age 25 and younger. The current Dr. Dynasaur program combines Vermont's Medicaid program and Child Health Insurance Program for children ages 0 through 18 to provide a seamless insurance program for those with family incomes below 317 percent of the federal poverty level. The authors used RAND's COMPARE-VT microsimulation model with Vermont-specific demographic, economic, and actuarial data to estimate the effects on health insurance coverage, costs, and premiums. They also identified the new revenues required to fund the program expansion and explored three alternative financing strategies to raise those funds: (1) an increase in the Vermont income tax, (2) a Vermont payroll tax, and (3) a Vermont business enterprise tax. The authors found that enrollment would increase by more than 260 percent under the 100-percent enrollment scenario and by nearly 200 percent under the 70-percent enrollment scenario by 2019. Not surprisingly, the children and young adults who move off employer-sponsored insurance (ESI) and into Dr. Dynasaur 2.0 have considerably lower expected health care costs than those who remain on ESI, increasing the per-person premiums by nearly $1,000 for those remaining enrolled in ESI. Annual health care expenditures per person for children and young adults in 2019 are estimated at $4,325 with Medicare prices. The combination of increased reimbursement rates, large increases in enrollment, and relatively low Dr. Dynasaur premiums (no more than $720 per year) will require significant new tax revenues to meet program obligations. PMID:29057152

  2. Collected Papers in Structural Mechanics Honoring Dr. James H. Starnes, Jr.

    NASA Technical Reports Server (NTRS)

    Knight, Norman F., Jr. (Compiler); Nemeth, Michael P. (Compiler); Malone, John B. (Compiler)

    2006-01-01

    This special publication contains a collection of structural mechanics papers honoring Dr. James H. Starnes, Jr. presented at the 46th AIAA/ASME/ASCE/AHS/ASC Structures, Structural Dynamics, and Materials Conference held in Austin, Texas, April 18-21, 2005. Contributors to this publication represent a small number of those influenced by Dr. Starnes' technical leadership, his technical prowess and diversity, and his technical breath and depth in engineering mechanics. These papers cover some of the research areas Dr. Starnes investigated, which included buckling, postbuckling, and collapse of structures; composite structural mechanics, residual strength and damage tolerance of metallic and composite structures; and aircraft structural design, certification and verification. He actively pursued technical understanding and clarity, championed technical excellence, and modeled humility and perseverance.

  3. Depths of channels in the area of the San Juan Basin Regional Uranium Study, New Mexico, Colorado, Arizona, and Utah

    USGS Publications Warehouse

    Cooley, Maurice E.

    1979-01-01

    During December 1977 and January 1978 about 280 measurements were made of the depths of channels (arroyos) more than 6 feet deep in the San Juan Basin area. More than half of the measurements were made at sites where channel depths had been previously measured Between 1964 and 1969. Some channels in the western part of the basin had Been re-measured in 1969 and in 1971. The principal areas Being dissected by arroyos are near highlands along the margins of the Basin and in uplands in the northeastern part of the Basin. The most severe dissection by arroyos and the deepest arroyos--commonly Between 40 and 60 feet deep--are in the southeastern part of the Basin. Dissection By arroyos is least in the central part of the Basin near the Chaco River where most arroyos are less than 10 feet deep. Elsewhere, moderate dissection predominates with most arroyos Between 12 and 40 feet deep. Comparison of measurements made from 1964-71 with those made in 1977-78 shows that more channels in the western San Juan Basin were filling than were downcutting. Downcutting or filling was generally less than 2 feet. About two-fifths of the sites measured showed less than half a foot of downcutting or filling. Maximum downcutting was 4 feet along the Rio San Jose in the southeastern part of the basin. Maximum filling of 7 feet was along the Chaco River at the Chaco Canyon National Monument. Along ii other streams elsewhere in the western part of the basin, channels were filled 3 to 4.5 feet. The few measurements made in the southeastern San Juan Basin indicate that since 1964 downcutting has predominated over filling. Large floods during the summer of 1977 caused some change in channel depths in the southwestern part of the San Juan Basin. Some of the channels appeared to have been filled during the years prior to the cutting that occurred from the 1977 floods. At other places, flood flows aggraded (filled) channels. The rate of erosion and arroyo formation in the entire San Juan Basin is

  4. A Numerical Study of the Urban Heat Island in the Coastal Tropical City of San Juan, Puerto Rico: Model Validation and Impacts of LCLU Changes

    NASA Technical Reports Server (NTRS)

    Comarazamy, Daniel E.; Gonzalez, Jorge E.; Luvall, Jeff; Rickman, Douglas L.

    2007-01-01

    Urban sprawls in tropical locations are rapidly accelerating and it is more evident in islands where a large percentage of the population resides along the coasts. This paper focuses on the analysis of the impacts of land use and land cover for urbanization in the tropical coastal city of San Juan, in the tropical island of Puerto Rico. A mesoscale numerical model, the Regional Atmospheric Modeling System (RAMS), is used to study specific characteristics and patterns of the urban heat island in the San Juan Metropolitan Area (SJMA), the most noticeable urban core of the Caribbean. The research present in this paper makes use of the observations obtained during the airborne San Juan Atlas Mission in two ways. First, surface and rawinsonde data are used to validate the atmospheric model yielding satisfactory results. Second, airborne remote sensing information is used to update the model's surface characteristics to obtain a detailed configuration of the SJMA in order to perform the LCLU changes impact analysis. This analysis showed that the presence of San Juan has an impact reflected in higher air temperatures over the area occupied by the city, with positive values of up to 2.5 C, for the simulations that have specified urban LCLU indexes in the bottom boundary. One interesting result of the impact analysis was the finding of a precipitation disturbance shown as a difference in total accumulated rainfall between simulation with the city and with a potential natural vegetation induced by the presence of the urban area. Model results indicate that the urban-induced cloud formation and precipitation development occur mainly downwind of the city, including the accumulated precipitation. This spatial pattern can be explained by the presence of a-larger urbanized area in the southwest sector of the city, and of the approaching northeasterly trade winds.

  5. Instituto Nacional de Electrification, Guatemala Load Dispatch Center and Global Communications Center. Feasibility report (Instituto Nacional de Electrificacion, Guatemala Centro Nacional de Despacho de Carga y Sistema Global de Comunicaciones). Export trade information

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1985-07-01

    The report presents the results of a feasibility study for the National Load Dispatch Center and Global Communications System Project in Guatemala. The project consists of a communication system which will provide Institute Nacional de Electrificacion (INDE) operations personnel direct voice access to all major power system facilities. In addition, a modern computer based load dispatch center has been configured on a secure and reliable basis to provide automatic generation control of all major interconnected generating plants within Guatemala.

  6. Biogeochemical variability of plants at native and altered sites, San Juan Basin, New Mexico

    USGS Publications Warehouse

    Gough, L.P.; Severson, R.C.

    1981-01-01

    The San Juan Basin is becoming a major energy resource region. The anticipated increase in strip mining for coal can be expected to alter the geochemical and biogeochemical environment. because such activities destroy the native vegetation communities, rearrange the rock strata, and disrupt natural soil development. This study investigated the variability in the biogeochemistry of native plant species at both undisturbed and altered sites and assessed the importance of the observed differences. Three studies are involved in this investigation: Study 1, the biogeochemical variability of native species found at sites throughout that part of the basin underlain by economically recoverable coal; Study 2, the biogeochemical variability of native species growing on soils considered favorable for use in the topsoiling of spoil areas; and Study 3, the biogeochemical variability of native species on rehabilitated sites at the San Juan coal mine. Summary statistics for concentrations of 35 elements (and ash yield) are reported in Study 1 for galleta grass, broom snakeweed, and fourwing saltbush. The concentrations of manganese, molybdenum, nickel, and uranium (and possibly iron and selenium) in galleta show regional patterns, with the highest values generally found in the south-central region and western edge of the study area. Differences in the concentration of elements between species was generally subtle (less than a factor of two) except for the following: ash yield of saltbush was two times that of the other plants; boron in snakeweed and saltbush was four times greater than in galleta; iron in galleta was two times greater than in saltbush; and, calcium, magnesium, potassium, phosphorus, and sulfur were generally highest in saltbush. Summary statistics (including the 95-percent expected range) for concentrations of 35 elements (and ash yield) are reported from Study 2 for galleta and broom snakeweed growing on the Sheppard, Shiprock, and Doak soil association

  7. Agonistic Human Monoclonal Antibodies against Death Receptor 4 (DR4) | NCI Technology Transfer Center | TTC

    Cancer.gov

    The National Cancer Institute is seeking parties interested in licensing human monoclonal antibodies (mAbs) that bind to death receptor 4 ("DR4"). The tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) and its functional receptors, DR4 and DR5, have been recognized as promising targets for cancer treatment.

  8. Alveolar epithelial cells in idiopathic pulmonary fibrosis display upregulation of TRAIL, DR4 and DR5 expression with simultaneous preferential over-expression of pro-apoptotic marker p53.

    PubMed

    Akram, Khondoker M; Lomas, Nicola J; Forsyth, Nicholas R; Spiteri, Monica A

    2014-01-01

    Idiopathic pulmonary fibrosis (IPF) is a progressive, debilitating, and fatal lung disease of unknown aetiology with no current cure. The pathogenesis of IPF remains unclear but repeated alveolar epithelial cell (AEC) injuries and subsequent apoptosis are believed to be among the initiating/ongoing triggers. However, the precise mechanism of apoptotic induction is hitherto elusive. In this study, we investigated expression of a panel of pro-apoptotic and cell cycle regulatory proteins in 21 IPF and 19 control lung tissue samples. We reveal significant upregulation of the apoptosis-inducing ligand TRAIL and its cognate receptors DR4 and DR5 in AEC within active lesions of IPF lungs. This upregulation was accompanied by pro-apoptotic protein p53 overexpression. In contrast, myofibroblasts within the fibroblastic foci of IPF lungs exhibited high TRAIL, DR4 and DR5 expression but negligible p53 expression. Similarly, p53 expression was absent or negligible in IPF and control alveolar macrophages and lymphocytes. No significant differences in TRAIL expression were noted in these cell types between IPF and control lungs. However, DR4 and DR5 upregulation was detected in IPF alveolar macrophages and lymphocytes. The marker of cellular senescence p21(WAF1) was upregulated within affected AEC in IPF lungs. Cell cycle regulatory proteins Cyclin D1 and SOCS3 were significantly enhanced in AEC within the remodelled fibrotic areas of IPF lungs but expression was negligible in myofibroblasts. Taken together these findings suggest that, within the remodelled fibrotic areas of IPF, AEC can display markers associated with proliferation, senescence, and apoptotosis, where TRAIL could drive the apoptotic response. Clear understanding of disease processes and identification of therapeutic targets will direct us to develop effective therapies for IPF.

  9. White dwarf-main sequence binaries from LAMOST: the DR5 catalogue

    NASA Astrophysics Data System (ADS)

    Ren, J.-J.; Rebassa-Mansergas, A.; Parsons, S. G.; Liu, X.-W.; Luo, A.-L.; Kong, X.; Zhang, H.-T.

    2018-03-01

    We present the data release (DR) 5 catalogue of white dwarf-main sequence (WDMS) binaries from the Large Area Multi-Object fiber Spectroscopic Telescope (LAMOST). The catalogue contains 876 WDMS binaries, of which 757 are additions to our previous LAMOST DR1 sample and 357 are systems that have not been published before. We also describe a LAMOST-dedicated survey that aims at obtaining spectra of photometrically-selected WDMS binaries from the Sloan Digital Sky Survey (SDSS) that are expected to contain cool white dwarfs and/or early type M dwarf companions. This is a population under-represented in previous SDSS WDMS binary catalogues. We determine the stellar parameters (white dwarf effective temperatures, surface gravities and masses, and M dwarf spectral types) of the LAMOST DR5 WDMS binaries and make use of the parameter distributions to analyse the properties of the sample. We find that, despite our efforts, systems containing cool white dwarfs remain under-represented. Moreover, we make use of LAMOST DR5 and SDSS DR14 (when available) spectra to measure the Na I λλ 8183.27, 8194.81 absorption doublet and/or Hα emission radial velocities of our systems. This allows identifying 128 binaries displaying significant radial velocity variations, 76 of which are new. Finally, we cross-match our catalogue with the Catalina Surveys and identify 57 systems displaying light curve variations. These include 16 eclipsing systems, two of which are new, and nine binaries that are new eclipsing candidates. We calculate periodograms from the photometric data and measure (estimate) the orbital periods of 30 (15) WDMS binaries.

  10. [Dr Guillermo Contreras Da Silva, a relevant figure in the development of Chilean microbiology].

    PubMed

    Cabello, Felipe C

    2008-02-01

    The influence of the work of Dr. Guillermo Contreras Da Silva and his colaborators on the evolution of microbiology in Chile is briefly analyzed. Dr. Contreras was trained in modern virology at Yale University with Dr. J. Melnick under the sponsorhip of the Rockefeller Foundation. During this training, he used serological methods to classify Cocksakie viruses. After his return to Chile, he studied the epidemiology of enteroviruses, including poliovirus. His laboratory, the country's first in modern virology, took an active role in Chile's first Sabin polio vaccination in 1961. Dr. Contreras and his group transformed the teaching and the character of microbiology in Chile from a descriptive medically oriented discipline into an autonomous, quantitative and experimental science. They modernized microbiology with the introduction of molecular biology and microbial genetics and fostered collaborations with allied biological sciences. Dr. Contreras was a Guggenheim Fellow, and until his retirement, was the Chief of the Viral Products Division, Bureau of Biologies, Ottawa, Canada.

  11. ORAC-DR -- spectroscopy data reduction

    NASA Astrophysics Data System (ADS)

    Hirst, Paul; Cavanagh, Brad

    ORAC-DR is a general-purpose automatic data-reduction pipeline environment. This document describes its use to reduce spectroscopy data collected at the United Kingdom Infrared Telescope (UKIRT) with the CGS4, UIST and Michelle instruments, at the Anglo-Australian Telescope (AAT) with the IRIS2 instrument, and from the Very Large Telescope with ISAAC. It outlines the algorithms used and how to make minor modifications of them, and how to correct for errors made at the telescope.

  12. Maniac Talk - Dr. Lorraine Remer

    NASA Image and Video Library

    2013-09-13

    Lorraine Remer Maniac Lecture, 9 September 2013 NASA climate scientist Dr. Lorraine Remer presented a Maniac Talk entitled "Girls Just Wanna Have Fun: Why I came to NASA and Why I left." Lorraine shared some of the aerosol science she has been involved in at NASA Goddard over the past 21 years, as well as a reflection on her route to becoming a NASA scientist and key factors that influenced her to leave a tenured job.

  13. A TRIBUTE TO DR. WILLIAM PENN WATKINSON

    EPA Science Inventory

    Dr. William Penn Watkinson (known to colleagues as "Penn") of EPA¿s health research lab (National Health and Environmental Research Laboratory) of Research Triangle Park, North Carolina, died Wednesday, December 13 after a battle with lung cancer. He was a member of the Pulmonar...

  14. ISAAC Photometric Comparison of ECLIPSE Jitter and the ORAC-DR Equivalent Recipe for ISAAC

    NASA Astrophysics Data System (ADS)

    Currie, M. J.

    2005-12-01

    Motivated by a request from astronomers demanding accurate and consistent infrared photometry, I compare the photometry and quality of mosaics generated by the ECLIPSE jitter task and the ORAC-DR JITTER_SELF_FLAT recipe in two fields. The current (v4.9.0) ECLIPSE produces photometry a few percent fainter than ORAC-DR; the systematic trend with magnitude seen in v4.4.1 is now removed. Random errors arising from poor flat-fielding are not resolved. ECLIPSE generates noisier mosaics; ORAC-DR has poorer bias removal in crowded fields and defaults to larger mosaics. ORAC-DR runs a few times slower than ECLIPSE, but its recipe development is measured in weeks, not years.

  15. High Temperature Superconductors: From Delivery to Applications (Presentation from 2011 Ernest Orlando Lawrence Award-winner, Dr. Amit Goyal, and including introduction by Energy Secretary, Dr. Steven Chu)

    ScienceCinema

    Goyal, Amit [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2018-04-27

    Dr. Amit Goyal, a high temperature superconductivity (HTS) researcher at Oak Ridge National Laboratory, was named a 2011 winner of the Department of Energy's Ernest Orlando Lawrence Award honoring U.S. scientists and engineers for exceptional contributions in research and development supporting DOE and its mission. Winner of the award in the inaugural category of Energy Science and Innovation, Dr. Goyal was cited for his work in 'pioneering research and transformative contributions to the field of applied high temperature superconductivity, including fundamental materials science advances and technical innovations enabling large-scale applications of these novel materials.' Following his basic research in grain-to-grain supercurrent transport, Dr. Goyal focused his energy in transitioning this fundamental understanding into cutting-edge technologies. Under OE sponsorship, Dr. Goyal co-invented the Rolling Assisted Bi-Axially Textured Substrate technology (RABiTS) that is used as a substrate for second generation HTS wires. OE support also led to the invention of Structural Single Crystal Faceted Fiber Substrate (SSIFFS) and the 3-D Self Assembly of Nanodot Columns. These inventions and associated R&D resulted in 7 R&D 100 Awards including the 2010 R&D Magazine's Innovator of the Year Award, 3 Federal Laboratory Consortium Excellence in Technology Transfer National Awards, a DOE Energy 100 Award and many others. As a world authority on HTS materials, Dr. Goyal has presented OE-sponsored results in more than 150 invited talks, co-authored more than 350 papers and is a fellow of 7 professional societies.

  16. High Temperature Superconductors: From Delivery to Applications (Presentation from 2011 Ernest Orlando Lawrence Award-winner, Dr. Amit Goyal, and including introduction by Energy Secretary, Dr. Steven Chu)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Goyal, Amit

    Dr. Amit Goyal, a high temperature superconductivity (HTS) researcher at Oak Ridge National Laboratory, was named a 2011 winner of the Department of Energy's Ernest Orlando Lawrence Award honoring U.S. scientists and engineers for exceptional contributions in research and development supporting DOE and its mission. Winner of the award in the inaugural category of Energy Science and Innovation, Dr. Goyal was cited for his work in 'pioneering research and transformative contributions to the field of applied high temperature superconductivity, including fundamental materials science advances and technical innovations enabling large-scale applications of these novel materials.' Following his basic research in grain-to-grainmore » supercurrent transport, Dr. Goyal focused his energy in transitioning this fundamental understanding into cutting-edge technologies. Under OE sponsorship, Dr. Goyal co-invented the Rolling Assisted Bi-Axially Textured Substrate technology (RABiTS) that is used as a substrate for second generation HTS wires. OE support also led to the invention of Structural Single Crystal Faceted Fiber Substrate (SSIFFS) and the 3-D Self Assembly of Nanodot Columns. These inventions and associated R&D resulted in 7 R&D 100 Awards including the 2010 R&D Magazine's Innovator of the Year Award, 3 Federal Laboratory Consortium Excellence in Technology Transfer National Awards, a DOE Energy 100 Award and many others. As a world authority on HTS materials, Dr. Goyal has presented OE-sponsored results in more than 150 invited talks, co-authored more than 350 papers and is a fellow of 7 professional societies.« less

  17. Monomeric DR2/MOG-35-55 recombinant TCR ligand treats relapses of experimental encephalomyelitis in DR2 transgenic mice.

    PubMed

    Link, Jason M; Rich, Cathleen M; Korat, Maya; Burrows, Gregory G; Offner, Halina; Vandenbark, Arthur A

    2007-04-01

    Treatment of human autoimmune diseases such as multiple sclerosis (MS) will likely require agents that can prevent or reverse the inflammatory process that results in clinical relapses and disease progression. We evaluated the ability of a newly designed monomeric recombinant TCR ligand (RTL342M) containing HLA-DR2 peptide-binding domains covalently linked to MOG-35-55 peptide to prevent and treat both the initial episode and subsequent relapses of experimental autoimmune encephalomyelitis (EAE) in HLA-DR2 transgenic mice. Single doses of RTL342M given either i.v. or s.c. to HLA-DR2 mice produced a rapid (within 24 h) and dose-dependent reversal of clinical signs of paralytic EAE, and even a single dose < or = 2 microg could produce a significant treatment effect. Multiple daily doses were even more effective than the same total amount of RTL given as a single dose. By establishing the minimal effective dose, we determined that RTLs may be 50 times more potent than molar equivalent doses of myelin peptide alone. RTL342M given prior to induction of EAE prevented disease in most mice, and the remainder could be successfully retreated with RTL. Most important for clinical application, RTL342M was highly effective for treating EAE relapses when given periodically prior to the relapse or even after relapses had occurred. These data demonstrate the rapid and potent clinical effects of RTL342M at disease onset and during relapses in EAE and establish important principles governing the application of this novel approach as a possible therapy for patients with MS.

  18. Loxosomella decorata n. sp., a new solitary entoproct from San Juan Island, WA, USA.

    PubMed

    Nielsen, Claus

    2017-03-06

    Several species of solitary entoprocts of the genera Loxosoma and Loxosomella occur on maldanid polychaetes or in their tubes (Nielsen 1964). New species turn up almost every time maldanids from new localities are studied, and the species described below has been the subject of a study of spiral cleavage (Merkel et al. 2012). This paper describes a new species of Loxosomella from tubes of the maldanid polychaete Axiothella rubrocincta (Johnson, 1901) from False Bay, San Juan Island, WA, USA.

  19. Dr. Andrew Foster: A Literature Review

    ERIC Educational Resources Information Center

    Runnels, Joel

    2017-01-01

    Often compared to Laurent Clerc, Thomas Gallaudet, and Alexander Graham Bell, Dr. Andrew Foster was a deaf African American who founded 32 schools for the deaf in 13 African nations. The 60th anniversary of his arrival in Liberia and Ghana and the 30th anniversary of his tragic death in a Rwanda airplane accident both occur in 2017. Renewed…

  20. ORAC-DR: Astronomy data reduction pipeline

    NASA Astrophysics Data System (ADS)

    Jenness, Tim; Economou, Frossie; Cavanagh, Brad; Currie, Malcolm J.; Gibb, Andy

    2013-10-01

    ORAC-DR is a generic data reduction pipeline infrastructure; it includes specific data processing recipes for a number of instruments. It is used at the James Clerk Maxwell Telescope, United Kingdom Infrared Telescope, AAT, and LCOGT. This pipeline runs at the JCMT Science Archive hosted by CADC to generate near-publication quality data products; the code has been in use since 1998.

  1. Occurrence, quality, and use of ground water in Orcas, San Juan, Lopez, and Shaw Islands, San Juan County, Washington

    USGS Publications Warehouse

    Whiteman, K.J.; Molenaar, Dee; Jacoby, J.M.; Bortleson, G.V.

    1983-01-01

    Ground water, which supplies most of San Juan County 's water needs, occurs in both bedrock and glacial drift. Water in the bedrock occurs in fractures in the otherwise dense, poorly permeable rock. Deposits of sand and gravel in the glacial drift provide the best yields to wells drilled into unconsolidated materials. Specific capacities of bedrock wells are typically low, and those of glacial-drift wells considerably higher. Ground water is high in dissolved solids and hardness; 29 of 56 wells sampled had water classified as very hard. Sixteen percent of the 171 ground-water sites tested for indicator bacteria had positive counts of one or more of these bacteria: total coliform , fecal coliform, fecal streptococcus. Nine percent of the 279 wells sampled for chloride in September 1981, appear to be affected by seawater intrusion. All of these wells are located within a mile of the coast; 60 percent of these wells are on Lopez Island. In 1980 an estimated total of 220 million gallons of ground water was withdrawn for all uses. Ninety percent of all ground-water use is for domestic and public supply purposes. Heavy pumpage on northern and southern Lopez Island correlates with areas having high chloride concentrations. (USGS)

  2. Completion reports, core logs, and hydrogeologic data from wells and piezometers in Prospect Gulch, San Juan County, Colorado

    USGS Publications Warehouse

    Johnson, Raymond H.; Yager, Douglas B.

    2006-01-01

    In the late nineteenth century, San Juan County, Colorado, was the center of a metal mining boom in the San Juan Mountains. Although most mining activity ceased by the 1990s, the effects of historical mining continue to contribute metals to ground water and surface water. Previous research by the U.S. Geological Survey identified ground-water discharge as a significant pathway for the loading of metals to surface water from both acid-mine drainage and acid-rock drainage. In an effort to understand the ground-water flow system in the upper Animas River watershed, Prospect Gulch was selected for further study because of the amount of previous data provided in and around that particular watershed. In support of this ground-water research effort, wells and piezometers were installed to allow for coring during installation, subsurface hydrologic testing, and the monitoring of ground-water hydraulic heads and geochemistry. This report summarizes the data that were collected during and after the installation of these wells and piezometers and includes (1) subsurface completion details, (2) locations and elevations, (3) geologic logs and elemental data, (4) slug test data for the estimation of subsurface hydraulic conductives, and (5) hydraulic head data.

  3. Tomography reveals buoyant asthenosphere accumulating beneath the Juan de Fuca plate

    NASA Astrophysics Data System (ADS)

    Hawley, William B.; Allen, Richard M.; Richards, Mark A.

    2016-09-01

    The boundary between Earth’s strong lithospheric plates and the underlying mantle asthenosphere corresponds to an abrupt seismic velocity decrease and electrical conductivity increase with depth, perhaps indicating a thin, weak layer that may strongly influence plate motion dynamics. The behavior of such a layer at subduction zones remains unexplored. We present a tomographic model, derived from on- and offshore seismic experiments, that reveals a strong low-velocity feature beneath the subducting Juan de Fuca slab along the entire Cascadia subduction zone. Through simple geodynamic arguments, we propose that this low-velocity feature is the accumulation of material from a thin, weak, buoyant layer present beneath the entire oceanic lithosphere. The presence of this feature could have major implications for our understanding of the asthenosphere and subduction zone dynamics.

  4. The Dr-nanos gene is essential for germ cell specification in the planarian Dugesia ryukyuensis.

    PubMed

    Nakagawa, Haruka; Ishizu, Hirotsugu; Chinone, Ayako; Kobayashi, Kazuya; Matsumoto, Midori

    2012-01-01

    Homologs of nanos are required for the formation and maintenance of germline stem cell (GSC) systems and for gametogenesis in many metazoans. Planarians can change their reproductive mode seasonally, alternating between asexual and sexual reproduction; they develop and maintain their somatic stem cells (SSCs) and GCSs from pluripotent stem cells known as neoblasts. We isolated a nanos homolog, Dr-nanos, from the expressed sequence tags (ESTs) of the sexualized form of Dugesia ryukyuensis. We examined the expression of Dr-nanos in asexual and sexualized planarians by in situ hybridization and analyzed its function using RNA interference (RNAi) together with a planarian sexualization assay. A nanos homolog, Dr-nanos, was identified in the planarian D. ryukyuensis. Dr-nanos expression was observed in the ovarian primordial cells of the asexual worms. This expression increased in proportion to sexualization and was localized in the early germline cells of the ovaries and testes. In X-ray-irradiated worms, the expression of Dr-nanos decreased to a large extent, indicating that Dr-nanos is expressed in some subpopulations of stem cells, especially in GSCs. During the sexualization process, worms in which Dr-nanos was knocked down by RNAi exhibited decreased numbers of oogonia in the ovaries and failed to develop testes, whereas the somatic sexual organs were not affected. We conclude that Dr-nanos is essential for the development of germ cells in the ovaries and testes and may have a function in the early stages of germ cell specification, but not in the development of somatic sexual organs.

  5. Dr. Ted Trimble: Why I Do Cancer Research

    Cancer.gov

    In a video, Dr. Ted Trimble talks about the importance of cancer research. World Cancer Research Day commemorates the important role research and cancer researchers play in reducing the global burden of cancer.

  6. [Two visions of the Arab immigrant: Juan A. Alsina and Santiago M. Peralta].

    PubMed

    Bestene, J O

    1997-08-01

    "Immigrants from [the] Middle East, mainly Syrian and Lebanese, play a relevant role among immigrants coming to Argentina since [the] mid 19th century.... Was the image of Arab immigrants in the 1940s similar to that at the turn of the century? Did their position in the local society soften the vision of them as ¿unwanted immigrants' in earlier times? Were there discriminatory behaviours against this ethnic group? We intend to answer [these] questions through the analysis of the discourse and the actions of two directors of the Argentine immigration department, i.e., Juan Alsina (1890-1910) and Santiago Peralta (1945-1947)." (EXCERPT)

  7. Chamber of Commerce reception for Dr. Lucas

    NASA Technical Reports Server (NTRS)

    1986-01-01

    Dr. William R. Lucas, Marshall's fourth Center Director (1974-1986), delivers a speech in front of a picture of the lunar landscape with Earth looming in the background while attending a Huntsville Chamber of Commerce reception honoring his achievements as Director of Marshall Space Flight Center (MSFC).

  8. ACHP | Q&A | The ACHP Interview: Dr. Julia King, associate professor of

    Science.gov Websites

    specific nav links Home arrow The ACHP Interview: Dr. Julia King, associate professor of archaeology and anthropology at St. Mary’s College of Maryland, expert member ACHP The ACHP Interview: Dr. Julia King With the recent Society for Historical Archaeology conference concluded, and former chairman John Nau

  9. Annotated Bibliography of Dr Salmani Nodoushan's Research on Education and Language Teaching

    ERIC Educational Resources Information Center

    Etemadfar Kashani, Abbas Ali

    2016-01-01

    This is an annotated bibliography of the research conducted on education and language teaching and assessment by Dr. Mohammad Ali Salmani Nodoushan in the past 25 years. This bibliography is a precise picture of the current state of education and language teaching and assessment in Iran. Dr. Salmani Nodoushan is the most distinguished Iranian…

  10. Climate-driven disturbances in the San Juan River sub-basin of the Colorado River

    DOE PAGES

    Bennett, Katrina E.; Bohn, Theodore J.; Solander, Kurt; ...

    2018-01-26

    Accelerated climate change and associated forest disturbances in the southwestern USA are anticipated to have substantial impacts on regional water resources. Few studies have quantified the impact of both climate change and land cover disturbances on water balances on the basin scale, and none on the regional scale. In this work, we evaluate the impacts of forest disturbances and climate change on a headwater basin to the Colorado River, the San Juan River watershed, using a robustly calibrated (Nash–Sutcliffe efficiency 0.76) hydrologic model run with updated formulations that improve estimates of evapotranspiration for semi-arid regions. Our results show that futuremore » disturbances will have a substantial impact on streamflow with implications for water resource management. Our findings are in contradiction with conventional thinking that forest disturbances reduce evapotranspiration and increase streamflow. In this study, annual average regional streamflow under the coupled climate–disturbance scenarios is at least 6–11 % lower than those scenarios accounting for climate change alone; for forested zones of the San Juan River basin, streamflow is 15–21 % lower. The monthly signals of altered streamflow point to an emergent streamflow pattern related to changes in forests of the disturbed systems. Exacerbated reductions of mean and low flows under disturbance scenarios indicate a high risk of low water availability for forested headwater systems of the Colorado River basin. Furthermore, these findings also indicate that explicit representation of land cover disturbances is required in modeling efforts that consider the impact of climate change on water resources.« less

  11. Seafloor Uplift in Middle Valley, Juan de Fuca Ridge: New High-Resolution Pressure Data

    NASA Astrophysics Data System (ADS)

    Inderbitzen, K. E.; Becker, K.; Davis, E. E.

    2011-12-01

    Currently, in-situ seafloor and basement pressures are continuously monitored and recorded by an ODP subseafloor hydrogeological observatory (CORK) located in Middle Valley, Juan de Fuca Ridge. Hole 857D was drilled in 1991 in thickly sedimented crust to a depth of 936 mbsf and instrumented with an original CORK that was replaced in 1996. A large hydrothermal field (Dead Dog) lies roughly 1.7 km north of the hole, and two isolated chimneys and several diffuse flow sites are located ~800 meters northeast. The borehole and the vent fields have been visited periodically by submersible/ROV since 1999. Recent results from the CORK at 857D have shown apparent seafloor uplift, supported by depth records from the submersible Alvin. A constant rate of pressure change of ~6 kPa/yr, from its initiation in 2005 to the visit in 2010, has reduced mean seafloor pressure by ~28 kPa, equivalent to nearly 3 meters of head. This uplift rate is several times the typical pre-eruption inflation rates observed at Axial Seamount further south along the Juan de Fuca Ridge. Initially, the apparent uplift at 857D did not seem to have any effect on local high-temperature hydrothermal venting, however recent operations in Middle Valley revealed distinct changes at not only the hydrothermal field to the northeast, but also a shutdown of high-temperature venting to the north of 857D. We will present new data from Middle Valley, including the first year of data collected by a high-resolution pressure data logger deployed at 857D in June, 2010.

  12. Use of geographic information system to display water-quality data from San Juan basin

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Thorn, C.R.; Dam, W.L.

    1989-09-01

    The ARC/INFO geographic information system is creating thematic maps of the San Juan basin as part of the USGS Regional Aquifer-System Analysis program. (Use of trade names is for descriptive purposes only and does not constitute endorsement by the US Geological Survey.) Maps created by a Prime version of ARC/INFO, to be published in a series of Hydrologic Investigations Atlas reports for selected geologic units, will include outcrop patters, water-well locations, and water-quality data. The San Juan basin study area, encompassing about 19,400 mi{sup 2}, can be displayed with ARC/INFO at various scales; on the same scale, generated water-quality mapsmore » can be compared and overlain with other maps such as potentiometric surface and depth to top of a geologic or hydrologic unit. Selected water-quality and well data (including latitude and longitude) are retrieved from the USGS National Water Information System data base for a specified geologic unit. Data are formatted by Fortran programs and read into an INFO data base. Two parallel files - an INFO file containing water-quality data and well data and an ARC file containing the site coordinates - are joined to form the ARC/INFO data base. A file containing a series of commands using Prime's Command Procedure language is used to select coverage, display, and position data on the map. Data interpretation is enhanced by displaying water-quality data throughout the basin in combination with other hydrologic and geologic data.« less

  13. Climate-driven disturbances in the San Juan River sub-basin of the Colorado River

    NASA Astrophysics Data System (ADS)

    Bennett, Katrina E.; Bohn, Theodore J.; Solander, Kurt; McDowell, Nathan G.; Xu, Chonggang; Vivoni, Enrique; Middleton, Richard S.

    2018-01-01

    Accelerated climate change and associated forest disturbances in the southwestern USA are anticipated to have substantial impacts on regional water resources. Few studies have quantified the impact of both climate change and land cover disturbances on water balances on the basin scale, and none on the regional scale. In this work, we evaluate the impacts of forest disturbances and climate change on a headwater basin to the Colorado River, the San Juan River watershed, using a robustly calibrated (Nash-Sutcliffe efficiency 0.76) hydrologic model run with updated formulations that improve estimates of evapotranspiration for semi-arid regions. Our results show that future disturbances will have a substantial impact on streamflow with implications for water resource management. Our findings are in contradiction with conventional thinking that forest disturbances reduce evapotranspiration and increase streamflow. In this study, annual average regional streamflow under the coupled climate-disturbance scenarios is at least 6-11 % lower than those scenarios accounting for climate change alone; for forested zones of the San Juan River basin, streamflow is 15-21 % lower. The monthly signals of altered streamflow point to an emergent streamflow pattern related to changes in forests of the disturbed systems. Exacerbated reductions of mean and low flows under disturbance scenarios indicate a high risk of low water availability for forested headwater systems of the Colorado River basin. These findings also indicate that explicit representation of land cover disturbances is required in modeling efforts that consider the impact of climate change on water resources.

  14. Climate-driven disturbances in the San Juan River sub-basin of the Colorado River

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bennett, Katrina E.; Bohn, Theodore J.; Solander, Kurt

    Accelerated climate change and associated forest disturbances in the southwestern USA are anticipated to have substantial impacts on regional water resources. Few studies have quantified the impact of both climate change and land cover disturbances on water balances on the basin scale, and none on the regional scale. In this work, we evaluate the impacts of forest disturbances and climate change on a headwater basin to the Colorado River, the San Juan River watershed, using a robustly calibrated (Nash–Sutcliffe efficiency 0.76) hydrologic model run with updated formulations that improve estimates of evapotranspiration for semi-arid regions. Our results show that futuremore » disturbances will have a substantial impact on streamflow with implications for water resource management. Our findings are in contradiction with conventional thinking that forest disturbances reduce evapotranspiration and increase streamflow. In this study, annual average regional streamflow under the coupled climate–disturbance scenarios is at least 6–11 % lower than those scenarios accounting for climate change alone; for forested zones of the San Juan River basin, streamflow is 15–21 % lower. The monthly signals of altered streamflow point to an emergent streamflow pattern related to changes in forests of the disturbed systems. Exacerbated reductions of mean and low flows under disturbance scenarios indicate a high risk of low water availability for forested headwater systems of the Colorado River basin. Furthermore, these findings also indicate that explicit representation of land cover disturbances is required in modeling efforts that consider the impact of climate change on water resources.« less

  15. Human radiation studies: Remembering the early years. Oral history of Dr. Nadine Foreman, M.D., August 19, 1994

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1995-07-01

    Dr. Nadine Foreman was interviewed by representatives of the US DOE Office of Human Radiation Experiments (OHRE). Dr. Foreman was selected for interview because of the position she held at the University of California, San Francisco. Following a brief biographical sketch, Dr. Foreman describes her work with Dr. Mayo Soley using I-131 in treatment of hyperthyroidism, selection criteria for patients in the radioiodine project, work with Dr. Earl Miller, work at Highland Hospital, radioiodine treatment of diffuse toxic goiter (myxedema), the radiophosphorus and radioiodine programs with Dr. Bert Low-Beer, and treatment of polycythemia vera.

  16. Doppler transcranien au cours de la drépanocytose chez l'enfant Malagasy

    PubMed Central

    Herinirina, Nicolas Fanantenana; Rajaonarison, Lova Hasina Ny Ony Narindra; Herijoelison, Andry Roussel; Rakoto, Olivat Aimée Alson; Ahmad, Ahmad

    2016-01-01

    Introduction Le doppler transcrânien est un outil efficace permettant de dépister les enfants drépanocytaires à risque d'AVC. Méthodes Nous avons réalisé une étude descriptive transversale sur des enfants Malagasy âgés entre 24 mois et 15 ans (groupe 1: 57 drépanocytaires, groupe 2: 43 témoins) afin d’évaluer le profil vélocimétrique des artères cérébrales chez les drépanocytaires. Un examen Doppler transcrânien a été réalisé avec étude des flux sanguins cérébraux chez les enfants des deux groupes. Résultats Pour les sujets drépanocytaires, la vitesse moyenne (VM) de l'artère cérébrale moyenne était de 100,9 ± 26,8 cm/s, l'indice de pulsatilité (IP) de 0,73 ± 0,20, la différence entre les artères cérébrales moyennes droite et gauche (ACMr) de 19,8 ± 21,5 cm/s, le rapport des vitesses de l'artère cérébrale antérieure/artère cérébrale moyenne (ACA/ACM) de 0,7 ± 0,2. Pour les enfants non drépanocytaires, VM: 80,6 ± 19,3 cm/s, IP: 0,79 ± 0,14, ACMr: 17 ± 20,1 cm/s, ACA/ACM: 0,8 ± 0,2. La vélocité des enfants drépanocytaires était supérieure au groupe contrôle. Les vitesses ont été corrélées avec le taux d'hémoglobine et l’âge et non pas avec le sexe et le volume globulaire moyen. Conclusion Les vitesses circulatoires cérébrales sont élevées chez les drépanocytaires que les enfants non drépanocytaires et sont influencées par le taux d'hémoglobine et l’âge. PMID:27516829

  17. PREFACE: Eighth International Conference on Dissociative Recombination (DR2010)

    NASA Astrophysics Data System (ADS)

    Guberman, Steven L.; Orel, Ann E.

    2011-07-01

    In dissociative recombination (DR), a molecular ion captures an electron and falls apart. One might initially conclude that this process is relatively simple. However, a review of the DR literature over the past 60 years, since the pioneering papers of Sir David Bates [1], shows that the study of DR has proved to be highly challenging for both theorists and experimentalists. Both this challenge and the ubiquitous importance of the process have made its study rewarding, endlessly interesting, and full of surprises. DR is fundamentally the interaction of an electronic continuum with a vibrational continuum often connected by quasibound intermediate states. Autoionization in the first continuum competes with dissociation in the second. DR occurs at the total energy of an ion plus a free electron and is in the same region as vibrationally excited Rydberg states and other neutral superexcited states. All these states interact with each other prior to dissociation, forming a complex that controls the quantum yields of products. The complexity of the process has required both innovation and ingenuity on the part of both theorists and experimentalists. Over the years, it has become apparent that in order to compare theoretical and experimental results, the experiments must identify the electronic, vibrational and for low mass ions, the rotational state. The traditional disagreement between theoretical and experimental results has been due, in part, to the sensitivity of DR cross sections and rate constants to the state of the recombining ion. Great progress has been made in recent years in both flowing afterglow and storage ring experiments aimed at reducing this uncertainty. The latest advances and insights in theory and experiment were the topics of the Eighth International Conference on Dissociative Recombination held at the Granlibakken Lodge at Lake, Tahoe, California, 16-20 August 2010. The conference was part of a series of conferences on DR that started at Chateau

  18. Fen Wetland Hydrology and Constraints on the Fate and Transport of Heavy Metals in the San Juan Mountains, Colorado

    NASA Astrophysics Data System (ADS)

    McClenning, B. K.; Marcantonio, F.; Giardino, J. R.

    2009-12-01

    The interactions of a variety of geomorphic processes and a complex geology have produced spectacular landscapes throughout the San Juan Mountains. This complex geology abounds in mineral deposits that were mined from the mid 1800s through the 1990s. Unfortunately, much of this early mining impacted the streams, lakes, groundwater, and fens in this environment. Today, mining is waning and interest in restoration of this alpine environment is growing. Thus, sustainable restoration requires understanding dynamic interactions in this environment, which mandates an evaluation of the geomorphic and hydrologic processes that shape the present landscape. Fen wetlands, which have developed in geologic niches produced by the intense glaciation of the San Juans, occur throughout the area. The San Juans primarily exhibit a radial drainage pattern, which continue to feed the wetlands. The hydrology of these wetlands controls the chemical and biological processes and may be the most important factor regulating fen wetland function and development. Hydrological models can be used to simulate these processes and to evaluate management scenarios for fen restoration. Five fens, located along glaciated valley floors at elevations of greater than 3,000 m, range in area from 0.4 km2 to 0.7 km2. These fens were compared to determine the influence of their morphometry on runoff and evapotranspiration. The fen hydrology is dominated by irregularly located and poorly linked pools. We are attempting to combine saturated-unsaturated groundwater flow and transport models to study each fen. Hydrological conditions within the fens, which act as a sink or filter for heavy metals, also play a major role in determining the fate of transport of contaminants associated with prior mining activities. Indeed, preliminary studies have found higher than normal concentrations of aluminum, cadmium, copper, iron, manganese, and zinc occurring throughout the San Juan wetlands. Lead is also thought to occur

  19. White dwarf-main sequence binaries from LAMOST: the DR5 catalogue

    NASA Astrophysics Data System (ADS)

    Ren, J.-J.; Rebassa-Mansergas, A.; Parsons, S. G.; Liu, X.-W.; Luo, A.-L.; Kong, X.; Zhang, H.-T.

    2018-07-01

    We present the data release (DR) 5 catalogue of white dwarf-main sequence (WDMS) binaries from the Large sky Area Multi-Object fibre Spectroscopic Telescope (LAMOST). The catalogue contains 876 WDMS binaries, of which 757 are additions to our previous LAMOST DR1 sample and 357 are systems that have not been published before. We also describe a LAMOST-dedicated survey that aims at obtaining spectra of photometrically selected WDMS binaries from the Sloan Digital Sky Survey (SDSS) that are expected to contain cool white dwarfs and/or early-type M dwarf companions. This is a population under-represented in previous SDSS WDMS binary catalogues. We determine the stellar parameters (white dwarf effective temperatures, surface gravities and masses, and M dwarf spectral types) of the LAMOST DR5 WDMS binaries and make use of the parameter distributions to analyse the properties of the sample. We find that, despite our efforts, systems containing cool white dwarfs remain under-represented. Moreover, we make use of LAMOST DR5 and SDSS DR14 (when available) spectra to measure the Na I λλ 8183.27, 8194.81 absorption doublet and/or Hα emission radial velocities of our systems. This allows identifying 128 binaries displaying significant radial velocity variations, 76 of which are new. Finally, we cross-match our catalogue with the Catalina Surveys and identify 57 systems displaying light-curve variations. These include 16 eclipsing systems, two of which are new, and nine binaries that are new eclipsing candidates. We calculate periodograms from the photometric data and measure (estimate) the orbital periods of 30 (15) WDMS binaries.

  20. Coal test drilling for the DE-NA-Zin Bisti Area, San Juan County, New Mexico

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wilson, R.W.; Jentgen, R.W.

    1980-01-01

    From October 1978 to June 1979, the US Geological Survey (USGS) drilled 51 test holes, and cored 9 holes, in the vicinity of the Bisti Trading Post in the southwestern part of the San Juan Basin, San Juan County, New Mexico. The drilling was done in response to expressions of interest received by the Bureau of Land Management concerning coal leasing and, in some places, badlands preservation. The object of the drilling was to determine the depth, thickness, extent, and quality of the coal in the Upper Cretaceous Fruitland Formation in northwest New Mexico. The holes were geophysically logged immediatelymore » after drilling. Resistivity spontaneous-potential, and natural gamma logs were run in all of the holes. A high-resolution density log was also run in all holes drilled before January 13, when a logging unit from the USGS in Albuquerque was available. After January 13, the holes were logged by a USGS unit from Casper, Wyoming that lacked density logging capabilities. At nine locations a second hole was drilled, about 20 ft from the first hole, down to selected coal-bearing intervals and the coal beds were cored. A detailed description of each of the cores is given on the page(s) following the logs for each hole. From these coal cores, 32 intervals were selected and submitted to the Department of Energy in Pittsburgh, Pennsylvania, for analysis.« less

  1. Modeling Dr. Dynasaur 2.0 Coverage and Finance Proposals: Effects of the Expansion of Vermont's Dr. Dynasaur Program to All Individuals Through Age 25.

    PubMed

    Dick, Andrew W; Price, Carter C; Woods, Dulani; Freund, Deborah Anne; McNamara, Martin; Schramm, Steven P; Berkman, Elrycc; Dehner, Tom

    2017-01-01

    The authors assessed an expansion of Vermont's Dr. Dynasaur program that would cover all residents age 25 and younger. The current Dr. Dynasaur program combines Vermont's Medicaid program and Child Health Insurance Program for children ages 0 through 18 to provide a seamless insurance program for those with family incomes below 317 percent of the federal poverty level. The authors used RAND's COMPARE-VT microsimulation model with Vermont-specific demographic, economic, and actuarial data to estimate the effects on health insurance coverage, costs, and premiums. They also identified the new revenues required to fund the program expansion and explored three alternative financing strategies to raise those funds: (1) an increase in the Vermont income tax, (2) a Vermont payroll tax, and (3) a Vermont business enterprise tax. The authors found that enrollment would increase by more than 260 percent under the 100-percent enrollment scenario and by nearly 200 percent under the 70-percent enrollment scenario by 2019. Not surprisingly, the children and young adults who move off employer-sponsored insurance (ESI) and into Dr. Dynasaur 2.0 have considerably lower expected health care costs than those who remain on ESI, increasing the per-person premiums by nearly $1,000 for those remaining enrolled in ESI. Annual health care expenditures per person for children and young adults in 2019 are estimated at $4,325 with Medicare prices. The combination of increased reimbursement rates, large increases in enrollment, and relatively low Dr. Dynasaur premiums (no more than $720 per year) will require significant new tax revenues to meet program obligations.

  2. Glaucoma: Eye-to-Eye with Dr. Rachel Bishop

    MedlinePlus

    ... of this page please turn JavaScript on. Feature: Glaucoma Eye-to-Eye with Dr. Rachel Bishop Past ... nerves are pale and cupped—signs of advanced glaucoma. Yet the patient wasn't aware of any ...

  3. Dr. von Braun Tours the North American Aviation

    NASA Technical Reports Server (NTRS)

    1962-01-01

    Dr. Wernher von Braun, Director of the Marshall Space Flight Center (MSFC), during his tour of the Space information Division of North American Aviation (NAA) in Downey, California, where the Saturn SII stage was developed.

  4. Dr. von Braun tours the North American Aviation

    NASA Technical Reports Server (NTRS)

    1962-01-01

    Dr. Wernher von Braun, Director of the Marshall Space Flight Center (MSFC), during his tour of the Space Information Division of North American Aviation (NAA) in Downey, California, where the Saturn SII stage was developed.

  5. Dr. William O. Coffee and his absorption cure for cataract.

    PubMed

    Ferry, A P

    1989-08-01

    Dr. William O. Coffee was an ophthalmologist who conducted an office and mail-order practice in the Midwest from the 1880s until 1927. His main stock in trade was a self-discovered absorption cure for a variety of ocular diseases, with particular emphasis on the medical cure of cataracts. Dr. Coffee's career was a checkered one, marked by dubious credentials, exuberant self-promotion, unlikely and exaggerated claims of medical successes, plagiarism, and rejection by the medical "establishment." Certain parallels may be drawn between his activities and some currently observed practices in ophthalmology.

  6. Dr. von Braun Visits Huntsville Boys Club

    NASA Technical Reports Server (NTRS)

    1961-01-01

    Dr. von Braun, Director of Marshall Space Flight Center (MSFC) and chairman of this year's United Givers Fund (UGF) drive at MSFC, takes time out from the problems of sending a man to the Moon to talk baseball with 11-year-old Randy Smith at the Huntsville Boys Club.

  7. VizieR Online Data Catalog: KiDS-ESO-DR3 multi-band source catalog (de Jong+, 2017)

    NASA Astrophysics Data System (ADS)

    de Jong, J. T. A.; Verdoes Kleijn, G. A.; Erben, T.; Hildebrandt, H.; Kuijken, K.; Sikkema, G.; Brescia, M.; Bilicki, M.; Napolitano, N. R.; Amaro, V.; Begeman, K. G.; Boxhoorn, D. R.; Buddelmeijer, H.; Cavuoti, S.; Getman, F.; Grado, A.; Helmich, E.; Huang, Z.; Irisarri, N.; La Barbera, F.; Longo, G.; McFarland, J. P.; Nakajima, R.; Paolillo, M.; Puddu, E.; Radovich, M.; Rifatto, A.; Tortora, C; Valentijn, E. A.; Vellucci, C.; Vriend, W-J.; Amon, A.; Blake, C.; Choi, A.; Fenech, Conti I.; Herbonnet, R.; Heymans, C.; Hoekstra, H.; Klaes, D.; Merten, J.; Miller, L.; Schneider, P.; Viola, M.

    2017-04-01

    KiDS-ESO-DR3 contains a multi-band source catalogue encompassing all publicly released tiles, a total of 440 survey tiles including the coadded images, weight maps, masks and source lists of 292 survey tiles of KiDS-ESO-DR3, adding to the 148 tiles released previously (50 in KiDS-ESO-DR1 and 98 in KiDS-ESO-DR2). (1 data file).

  8. Analysis of the Transport and Fate of Metals Released From the Gold King Mine in the Animas and San Juan Rivers

    EPA Science Inventory

    This project’s objectives were to provide analysis of water quality following the release of acid mine drainage in the Animas and San Juan Rivers in a timely manner to 1) generate a comprehensive picture of the plume at the river system level, 2) help inform future monitoring eff...

  9. [Homage to Professor Dr. Nicasio Etchepareborda].

    PubMed

    1998-11-01

    During a solemn academic act, de Main Classroom of the Facultad de Odontologia de Buenos Aires was named after Prof. Dr. Nicasio Etchepareborda. He has been the first professor at the Escuela de Odontologia and its organizer, after having obtained his Dentistry degree at the Dental School of Paris, in 1882. The new school was founded in 1891, and its activities began the following year.

  10. DR5 mAb-conjugated, DTIC-loaded immuno-nanoparticles effectively and specifically kill malignant melanoma cells in vivo.

    PubMed

    Ding, Baoyue; Zhang, Wei; Wu, Xin; Wang, Jeffrey; Xie, Chen; Huang, Xuan; Zhan, Shuyu; Zheng, Yongxia; Huang, Yueyan; Xu, Ningyin; Ding, Xueying; Gao, Shen

    2016-08-30

    We combined chemo- and immunotherapies by constructing dual therapeutic function immuno-nanoparticles (NPs) consisting of death receptor 5 monoclonal antibody (DR5 mAb)-conjugated nanoparticles loaded with dacarbazine (DTIC) (DTIC-NPs-DR5 mAb). We determined the in vivo targeting specificity of DTIC-NPs-DR5 mAb by evaluating distribution in tumor-bearing nude mice using a real-time imaging system. Therapeutic efficacy was assessed in terms of its effect on tumor volume, survival time, histomorphology, microvessel density (MVD), and apoptotic index (AI). Systemic toxicity was evaluated by measuring white blood cells (WBC) counts, alanine aminotransferase (ALT) levels, and creatinine clearance (CR).In vivo and ex vivo imaging indicates that DR5 mAb modification enhanced the accumulation of NPs within the xenograft tumor. DTIC-NPs-DR5 mAb inhibited tumor growth more effectively than DTIC or DR5 mAb alone, indicating that combining DTIC and DR5 mAb through pharmaceutical engineering achieves a better therapeutic effect. Moreover, the toxicity of DTIC-NPs-DR5 mAb was much lower than that of DTIC, implying that DR5 mAb targeting reduces nonspecific uptake of DTIC into normal tissue and thus decreases toxic side effects. These results demonstrate that DTIC-NPs-DR5 mAb is a safe and effective nanoparticle formulation with the potential to improve the efficacy and specificity of melanoma treatment.

  11. Analysis of Upper Air, Ground and Remote Sensing Data for the ATLAS Field Campaign in San Juan, Puerto Rico

    NASA Technical Reports Server (NTRS)

    Gonzalez, Jorge E.; Luvall, Jeff; Rickman, Douglas; Comarazamy, Daniel; Picon, Ana J.

    2005-01-01

    The Atlas San Juan Mission was conducted in February 2004 with the main objectives of observing the Urban Heat Island of San Juan, providing high resolution data of the land use for El Yunque Rain Forest and for calibrating remote sensors. The mission was coordinated with NASA staff members at Marsha& Stennis, Goddard, and Glenn. The Airborne Thermal and Land Applications Sensor (ATLAS) from NASA/Stennis, that operates in the visual and IR bands, was used as the main sensor and was flown over Puerto Rico in a Lear 23 jet plane. To support the data gathering effort by the ATLAS sensor, remote sensing observations and upper air soundings were conducted along with the deployment of a number of ground based weather stations and temperature sensors. This presentation focuses in the analysis of this complementary data for the Atlas San Juan Mission. Upper air data show that during the days of the mission the Caribbean mid and high atmospheres were relatively dry and highly stable reflecting positive surface lifted index, a necessary condition to conduct this suborbital campaign. Surface wind patterns at levels below 850mb were dominated by the easterly trades, while the jet stream at the edge of the troposphere dominated the westerly wind at levels above 500mb. The jet stream remained at high latitudes reducing the possibility of fronts. In consequence, only 8.4 mm of precipitation were reported during the entire mission. Observation of soundings located about 150 km apart reflected minimum variations of the boundary layer across the Island for levels below 850 meters and a uniform atmosphere for higher levels. The weather stations and the temperature sensors were placed at strategic locations to observe variations across the urban and rural landscapes. Time series plot of the stations' data show that heavily urbanized commercial areas have higher air temperatures than urban and suburban residential areas, and much higher temperatures than rural areas. Temperature

  12. Analysis of Upper Air, Ground and Remote Sensing Data For the ATLAS Field Campaign in San Juan, Puerto Rico

    NASA Technical Reports Server (NTRS)

    Gonzalez, J. E.; Luvall, J. C.; Rickman, D.; Comarazamy, D. E.; Picon, A.

    2004-01-01

    The Atlas San Juan Mission was conducted in February 2004 with the main objectives of observing the Urban Heat Island of San Juan, providing high resolution data of the land use for El Yunque Rain Forest and for calibrating remote sensors. The mission was coordinated with NASA staff members at Marshall, Stennis, Goddard, and Glenn. The Airborne Thermal and Land Applications Sensor (ATLAS) from NASA/Stennis, that operates in the visual and IR bands, was used as the main sensor and was flown over Puerto Rico in a Lear 23 jet plane. To support the data gathering effort by the ATLAS sensor, remote sensing observations and upper air soundings were conducted along with the deployment of a number of ground based weather stations and temperature sensors. This presentation focuses in the analysis of this complementary data for the Atlas San Juan Mission. Upper air data show that during the days of the mission the Caribbean mid and high atmospheres were relatively dry and highly stable reflecting positive surface lifted index, a necessary condition to conduct this suborbital campaign. Surface wind patterns at levels below 850mb were dominated by the easterly trades, while the jet stream at the edge of the troposphere dominated the westerly wind at levels above 500mb. The jet stream remained at high latitudes reducing the possibility of fronts. In consequence, only 8.4 mm of precipitation were reported during the entire mission. Observation of soundings located about 150 km apart reflected minimum variations of the boundary layer across the island for levels below 850 meters and a uniform atmosphere for higher levels. The weather stations and the temperature sensors were placed at strategic locations to observe variations across the urban and rural landscapes. Time series plot of the stations' data show that heavily urbanized commercial areas have higher air temperatures than urban and suburban residential areas, and much higher temperatures than rural areas. Temperature

  13. Dr. Caleb Williams Saleeby: The Complete Eugenicist.

    ERIC Educational Resources Information Center

    Rodwell, Grant

    1997-01-01

    Profiles the work of Dr. Caleb Williams Saleeby, a late 19th-century propagandist for eugenics. Eugenics is a science that deals with the transmission of hereditary racial traits, coupled with a desire to use this for the elimination of social ills. Discusses Saleeby's work with the Eugenics Education Society. (MJP)

  14. Dr. Omalu Talks Childhood, Concussions, and CTE | Poster

    Cancer.gov

    Dr. Bennet Omalu, the famed forensic pathologist who discovered Chronic Traumatic Encephalopathy (CTE), recently spoke at NCI at Frederick about his upbringing as well as the trials he faced while working to educate the NFL about CTE.

  15. AgRISTARS: Renewable resources inventory. Land information support system implementation plan and schedule. [San Juan National Forest pilot test

    NASA Technical Reports Server (NTRS)

    Yao, S. S. (Principal Investigator)

    1981-01-01

    The planning and scheduling of the use of remote sensing and computer technology to support the land management planning effort at the national forests level are outlined. The task planning and system capability development were reviewed. A user evaluation is presented along with technological transfer methodology. A land management planning pilot test of the San Juan National Forest is discussed.

  16. Shallow Mantle Anisotropy Beneath the Juan de Fuca Plate

    NASA Astrophysics Data System (ADS)

    VanderBeek, Brandon P.; Toomey, Douglas R.

    2017-11-01

    The anisotropic fabric of the oceanic mantle lithosphere is often assumed to parallel paleo-relative plate motion (RPM). However, we find evidence that this assumption is invalid beneath the Juan de Fuca (JdF) plate. Using travel times of seismic energy propagating through the topmost mantle, we find that the fast direction of P wave propagation is rotated 18° ± 3° counterclockwise to the paleo-spreading direction and strikes between Pacific-JdF relative and JdF absolute plate motion (APM). The mean mantle velocity is 7.85 ± 0.02 km/s with 4.6% ± 0.4% anisotropy. Synthesis of the plate-averaged Pn anisotropy signal with measurements of Pn anisotropy beneath the JdF Ridge and SKS splits across the JdF plate suggests that the anisotropic structure of the topmost mantle continues to evolve away from the spreading center to more closely align with APM. We infer that the oceanic mantle lithosphere may record the influence of both paleo-RPM and paleo-APM.

  17. [Preparation and application of monoclonal antibodies against DR region of Na+-K+-ATPase α1 subunit].

    PubMed

    Yan, Xiaofei; Wu, Litao; DU, Xiaojuan; Li, Jing; Zhang, Fujun; Han, Yan; Lyu, Shemin; Li, Dongmin

    2016-12-01

    Objective To prepare monoclonal antibodies against DR region (897DVEDSYGQQWTYEQR911) of Na + -K + -ATPase α1 subunit and identify their properties. Methods BALB/c mice were immunized with DR-keyholelimpet hemocyanin (KLH). Splenocytes from the immunized mice were collected and subsequently fused with SP2/0 mouse myeloma cells. Positive hybridoma clones were obtained after cell fusion and selection. ELISA was used to detect DR antibody titer in the cell supernatants. DR region-specific monoclonal antibodies were analyzed by dot blotting, Western blotting and immunofluorescence assay. Na + -K + -ATPase activity was detected by SensoLyte R FDP Protein Phosphatase Assay Kit and the protective effect of the monoclonal antibody against high glucose-induced cell injury was assessed in H9c2 cells. Results Three hybridoma cell lines which secreted stable DR monoclonal antibody were obtained. The strongest positive cell line, named DRm217, was selected to prepare ascites. Dot blotting, Western blotting and immunofluorescence assay showed that DRm217 recognized specially DR region of Na + -K + -ATPase and bound on H9c2 cell membranes. DRm217 stimulated Na + -K + -ATPase activity and alleviated high glucose-induced H9c2 cells injury. Conclusion The monoclonal antibodies against DR region of Na + -K + -ATPase α1 subunit is prepared.

  18. Ordovidan K-bentonites in the Precordillera of San Juan and its tectomasmatic significance

    USGS Publications Warehouse

    Cingolani, C.A.; Huff, W.; Bergstrom, S.; Kolata, D.

    1997-01-01

    A succession of approximately 35 early Middle Ordovician K-bentonite beds are exposed in the Precordillera region near the town of Jachal, in San Juan Province (at Cerro Viejo and La Chilca sections). They occur in argillaceous limestone in the upper part of the San Juan Limestone and in the interbedded shales and mudstones at the base of the overlying Los Azules Formation. Total thickness of the K-bentonite-bearing interval is 23 m and individual beds range from 1 to 65 cm thick. An essentially Arenig-Llanvirn age for the K-bentonite succession is indicated by the presence of graptolites diagnostic of the Paraglossograptus tentaculatus Zone and conodonts indicating the Eoplacognathus suecicus Zone. The bentonites consist mainly of Rl ordered illite/smectite, characteristic of most of the lower Paleozoic K-bentonites, plus volcanogenic crystals. Similar to other K-bentonites, these probably represent the distal, glass-rich portion of fall-out ash beds derived from collision zone explosive volcanism. The geochemical data and preliminary plots on the magmatic discrimination diagram indicate the parental magma was of rhyolite to trachyandesite composition. Tectonic discrimination diagrams show the setting of Cerro Viejo ash layers as falling on the boundary between volcanic arc and within plate rocks, typical of collision margin felsic volcanic rocks. U-Pb isotope dating for two zircon fractions from one sample show a lower concordia intercept of 461, +7-10 Ma coincident with the biostratigraphic age. Thus, they have important implications for the origin and early history of the allochtonous Precordillera terrane and the Pacific margin of South America. Furthermore, they are potentially important in interpretations of the paleogeographic relations of Laurentia and Gondwana during Ordovician time. ?? 1997 Asociacio??n Geolo??gica Argentina.

  19. Plasma Exosomes Contribute to Microvascular Damage in Diabetic Retinopathy (DR) by Activating Classical Complement Pathway.

    PubMed

    Huang, Chao; Fisher, Kiera P; Hammer, Sandra S; Navitskaya, Svetlana; Blanchard, Gary J; Busik, Julia V

    2018-06-04

    Diabetic Retinopathy (DR) is a micro-vascular complication of diabetes and is the leading cause of vision loss in working-age adults. Recent studies have implicated the complement system as an emerging player in development of vascular damage and progression of DR. However, the role and activation of the complement system in DR is not well understood. Exosomes, small vesicles that are secreted into the extracellular environment, have a cargo of complement proteins in plasma suggesting that they can participate in causing vascular damage associated with DR. We demonstrate that IgG-laden exosomes in plasma activate the classical complement pathway, and that the quantity of these exosomes is increased in diabetes. Moreover, we show that lack of IgG in exosomes results in a reduction of retinal vascular damage in diabetic mice. Together, the results of this study demonstrate that complement activation by IgG-laden plasma exosomes could contribute to the development of DR. © 2018 by the American Diabetes Association.

  20. Tomography reveals buoyant asthenosphere accumulating beneath the Juan de Fuca plate.

    PubMed

    Hawley, William B; Allen, Richard M; Richards, Mark A

    2016-09-23

    The boundary between Earth's strong lithospheric plates and the underlying mantle asthenosphere corresponds to an abrupt seismic velocity decrease and electrical conductivity increase with depth, perhaps indicating a thin, weak layer that may strongly influence plate motion dynamics. The behavior of such a layer at subduction zones remains unexplored. We present a tomographic model, derived from on- and offshore seismic experiments, that reveals a strong low-velocity feature beneath the subducting Juan de Fuca slab along the entire Cascadia subduction zone. Through simple geodynamic arguments, we propose that this low-velocity feature is the accumulation of material from a thin, weak, buoyant layer present beneath the entire oceanic lithosphere. The presence of this feature could have major implications for our understanding of the asthenosphere and subduction zone dynamics. Copyright © 2016, American Association for the Advancement of Science.

  1. The clinical impact of the novel tumor marker DR-70 in unresectable gastric cancer patients.

    PubMed

    Hung, Yi-Ping; Chen, Ming-Huang; Lin, June-Seng; Hsiao, Chin-Fu; Shan, Yan-Shen; Chen, Yeu-Chin; Chen, Li-Tzong; Liu, Tsang-Wu; Li, Chung-Pin; Chao, Yee

    2018-07-01

    Gastric cancer tumor markers, such as carcinoembryonic antigen (CEA) and cancer antigen 19-9 (CA 19-9), have been applied in clinical practice to screen or monitor treatment responses. However, their sensitivity and specificity are unsatisfactory. Therefore, we assessed the novel tumor marker DR-70 and evaluated its performance in screening and response monitoring. The study included newly diagnosed patients with advanced gastric cancer from March 2012 to October 2015. We measured the DR-70, CEA, and CA 19-9 levels at the time of enrollment. The patients subsequently underwent chemotherapy. We followed-up the patients every 3 months; DR-70 levels and abdominal computed tomography scans were re-evaluated and repeated, respectively, at each follow-up. The correlation between treatment response and DR-70 level after chemotherapy was analyzed. The overall survival and progression-free survival rates were also evaluated. A total of 51 patients with gastric cancer were enrolled. Most (82.4%) had metastatic disease. At enrollment, the sensitivity of DR-70 in our study group was 78.4%, compared with 52.9% and 43.1% for CEA and CA 19-9, respectively. When we used the three tumor markers together, the sensitivity increased to 80.4%. We observed a correlation between treatment response and DR-70 level after chemotherapy. No difference in either overall survival or progression-free survival was observed between the DR-70 positive and negative groups. However, a trend toward poorer overall survival was observed for the high DR-70 group, although this was not statistically significant. DR-70 is a powerful tool not only for screening unresectable gastric cancer but also for treatment response evaluation. Copyright © 2018. Published by Elsevier Taiwan LLC.

  2. DR5 mAb-conjugated, DTIC-loaded immuno-nanoparticles effectively and specifically kill malignant melanoma cells in vivo

    PubMed Central

    Wang, Jeffrey; Xie, Chen; Huang, Xuan; Zhan, Shuyu; Zheng, Yongxia; Huang, Yueyan; Xu, Ningyin; Ding, Xueying; Gao, Shen

    2016-01-01

    We combined chemo- and immunotherapies by constructing dual therapeutic function immuno-nanoparticles (NPs) consisting of death receptor 5 monoclonal antibody (DR5 mAb)-conjugated nanoparticles loaded with dacarbazine (DTIC) (DTIC-NPs-DR5 mAb). We determined the in vivo targeting specificity of DTIC-NPs-DR5 mAb by evaluating distribution in tumor-bearing nude mice using a real-time imaging system. Therapeutic efficacy was assessed in terms of its effect on tumor volume, survival time, histomorphology, microvessel density (MVD), and apoptotic index (AI). Systemic toxicity was evaluated by measuring white blood cells (WBC) counts, alanine aminotransferase (ALT) levels, and creatinine clearance (CR).In vivo and ex vivo imaging indicates that DR5 mAb modification enhanced the accumulation of NPs within the xenograft tumor. DTIC-NPs-DR5 mAb inhibited tumor growth more effectively than DTIC or DR5 mAb alone, indicating that combining DTIC and DR5 mAb through pharmaceutical engineering achieves a better therapeutic effect. Moreover, the toxicity of DTIC-NPs-DR5 mAb was much lower than that of DTIC, implying that DR5 mAb targeting reduces nonspecific uptake of DTIC into normal tissue and thus decreases toxic side effects. These results demonstrate that DTIC-NPs-DR5 mAb is a safe and effective nanoparticle formulation with the potential to improve the efficacy and specificity of melanoma treatment. PMID:27494835

  3. Data from Dr. Douglas Matson's aerodynamic levitator being analy

    NASA Image and Video Library

    2017-10-20

    Sangho Jeon (Tufts University), Thomas Leitner (Graz University of Technology), and Trudy Allen analyze data from Dr. Douglas Matson's aerodynamic levitator in support of his MaterialsLab experiments.

  4. A tribute to Dr. Gordon Hisashi Sato (December 24, 1927-March 31, 2017).

    PubMed

    Sato, J Denry; Okamoto, Tetsuji; Barnes, David; Hayashi, Jun; Serrero, Ginette; McKeehan, Wallace L

    2018-03-01

    Gordon H. Sato, an innovator in mammalian tissue culture and integrated cellular physiology, passed away in 2017. In tribute to Dr. Sato, In Vitro Cellular and Developmental Biology-Animal presents a collection of invited remembrances from six colleagues whose associations with Dr. Sato spanned more than 40 years. Dr. Sato was a past president of the Tissue Culture Association (now the Society for In Vitro Biology), editor-in-chief of In Vitro Cellular and Developmental Biology (1987-1991), and the recipient of the lifetime achievement award from the Society for In Vitro Biology (2002). He was elected to the US National Academy of Sciences in 1984.

  5. Conserved extended haplotypes discriminate HLA-DR3-homozygous Basque patients with type 1 diabetes mellitus and celiac disease.

    PubMed

    Bilbao, J R; Calvo, B; Aransay, A M; Martin-Pagola, A; Perez de Nanclares, G; Aly, T A; Rica, I; Vitoria, J C; Gaztambide, S; Noble, J; Fain, P R; Awdeh, Z L; Alper, C A; Castaño, L

    2006-10-01

    The major susceptibility locus for type 1 diabetes mellitus (T1D) maps to the human lymphocyte antigen (HLA) class II region in the major histocompatibility complex on chromosome 6p21. In southern European populations, like the Basques, the greatest risk to T1D is associated with DR3 homo- and heterozygosity and is comparable to that of DR3/DR4, the highest risk genotype in northern European populations. Celiac disease (CD) is another DR3-associated autoimmune disorder showing certain overlap with T1D that has been explained by the involvement of common genetic determinants, a situation more frequent in DR3-rich populations, like the Basques. As both T1D- and CD-associated HLA alleles are part of conserved extended haplotypes (CEH), we compared DR3-homozygous T1D and CD patients to determine whether CEHs were equally distributed between both disorders or there was a differential contribution of different haplotypes. We observed a very pronounced distribution bias (P<10(-5)) of the two major DR3 CEHs, with DR3-B18 predominating in T1D and DR3-B8 in CD. Additionally, high-density single nucleotide polymorphism (SNP) analysis of the complete CEH [A*30-B*18-MICA*4-F1C30-DRB1*0301-DQB1*0201-DPB1*0202] revealed extraordinary conservation throughout the 4.9 Mbp analyzed supporting the existence of additional diabetogenic variants (other than HLA-DRB1*0301-DQB1*0201), conserved within the DR3-B18 CEH (but not in other DR3 haplotypes) that could explain its enhanced diabetogenicity.

  6. Precise age of C33N-C32R magnetic-polarity reversal, San Juan Basin, New Mexico and Colorado

    USGS Publications Warehouse

    Fassett, James E.; Steiner, Maureen B.

    1997-01-01

    Polarity-chron boundary C33n-C32r has been identified in the Upper Cretaceous continental Farmington Sandstone Member of the Kirtland Shale in Hunter Wash in the southwest part of the San Juan Basin of New Mexico, and in the marine Lewis Shale at Chimney Rock, Colorado, in the northeast part of the basin. Single- and multiple-crystal laser fusion 40Ar/39Ar ages of sanidine crystals from volcanic ash beds bracketing the C33n-C32r polarity reversal at Hunter Wash establish its age as 73.50 ± 0.18 Ma. The reversal apparently occurs within the Baculites compressus Western Interior ammonite zone and within the Edmontonian land-vertebrate faunal zone. An 8 Ma hiatus separates Cretaceous and Tertiary rocks in the southern San Juan Basin. These findings provide a precise new interpolated Late Cretaceous tie point for geologic time scales, provide the basis for the direct correlation of Western Interior ammonite zones to European open-ocean faunal zones, and establish the first direct tie between continental and marine fossil zones within the Western Interior of North America.

  7. Dr. Kenneth Sudduth: A giant pioneering precision agriculture

    USDA-ARS?s Scientific Manuscript database

    Dr. Ken Sudduth is nationally and internationally recognized for his precision agriculture research and leadership, especially in the areas of soil sensing and assessment of spatial variability for site-specific management. His many noteworthy contributions include novel techniques and methodology f...

  8. ORAC-DR -- imaging data reduction

    NASA Astrophysics Data System (ADS)

    Currie, Malcolm J.; Cavanagh, Brad

    ORAC-DR is a general-purpose automatic data-reduction pipeline environment. This document describes its use to reduce imaging data collected at the United Kingdom Infrared Telescope (UKIRT) with the UFTI, UIST, IRCAM, and Michelle instruments; at the Anglo-Australian Telescope (AAT) with the IRIS2 instrument; at the Very Large Telescope with ISAAC and NACO; from Magellan's Classic Cam, at Gemini with NIRI, and from the Isaac Newton Group using INGRID. It outlines the algorithms used and how to make minor modifications to them, and how to correct for errors made at the telescope.

  9. DR3 regulation of apoptosis of naive T-lymphocytes in children with acute infectious mononucleosis.

    PubMed

    Filatova, Elena Nikolaevna; Anisenkova, Elena Viktorovna; Presnyakova, Nataliya Borisovna; Utkin, Oleg Vladimirovich

    2016-09-01

    Acute infectious mononucleosis (AIM) is a widespread viral disease that mostly affects children. Development of AIM is accompanied by a change in the ratio of immune cells. This is provided by means of different biological processes including the regulation of apoptosis of naive T-cells. One of the potential regulators of apoptosis of T-lymphocytes is a death receptor 3 (DR3). We have studied the role of DR3 in the regulation of apoptosis of naive CD4 + (nTh) and CD8 + (nCTL) T-cells in healthy children and children with AIM. In healthy children as well as in children with AIM, the activation of DR3 is accompanied by inhibition of apoptosis of nTh. In healthy children, the stimulation of DR3 resulted in the increase in apoptosis of nCTL. On the contrary, in children with AIM, the level of apoptosis of nCTL decreased after DR3 activation, which is a positive contribution to the antiviral immune response. In children with AIM, nCTL are characterized by reduced level of apoptosis as compared with healthy children. These results indicate that DR3 can be involved in the reduction of sensitivity of nCTL to apoptosis in children with AIM.

  10. [Juan Valverde de Amusco c. 1525-1588 and his vocation for anatomy in the Hispano-Italian Renaissance].

    PubMed

    Hernández-Mansilla, José Miguel

    2015-01-01

    The XVIth century witnessed a glorious period in the progress of some of the basic medical sciences among which anatomy stands out. One of the well-known figures involved in the development of this subject was Juan Valverde de Amusco, a notable Spanish scientist. This research shows the most relevant data currently known on his life, sociocultural environment and his celebrated treaty on anatomy titled: "Historia de la composición del cuerpo humano". (History of the human body).

  11. GENESI-DR: Discovery, Access and on-Demand Processing in Federated Repositories

    NASA Astrophysics Data System (ADS)

    Cossu, Roberto; Pacini, Fabrizio; Parrini, Andrea; Santi, Eliana Li; Fusco, Luigi

    2010-05-01

    GENESI-DR (Ground European Network for Earth Science Interoperations - Digital Repositories) is a European Commission (EC)-funded project, kicked-off early 2008 lead by ESA; partners include Space Agencies (DLR, ASI, CNES), both space and no-space data providers such as ENEA (I), Infoterra (UK), K-SAT (N), NILU (N), JRC (EU) and industry as Elsag Datamat (I), CS (F) and TERRADUE (I). GENESI-DR intends to meet the challenge of facilitating "time to science" from different Earth Science disciplines in discovery, access and use (combining, integrating, processing, …) of historical and recent Earth-related data from space, airborne and in-situ sensors, which are archived in large distributed repositories. In fact, a common dedicated infrastructure such as the GENESI-DR one permits the Earth Science communities to derive objective information and to share knowledge in all environmental sensitive domains over a continuum of time and a variety of geographical scales so addressing urgent challenges such as Global Change. GENESI-DR federates data, information and knowledge for the management of our fragile planet in line with one of the major goals of the many international environmental programmes such as GMES, GEO/GEOSS. As of today, 12 different Digital Repositories hosting more than 60 heterogeneous dataset series are federated in GENESI-DR. Series include satellite data, in situ data, images acquired by airborne sensors, digital elevation models and model outputs. ESA has started providing access to: Category-1 data systematically available on Internet; level 3 data (e.g., GlobCover map, MERIS Global Vegetation Index); ASAR products available in ESA Virtual Archive and related to the Supersites initiatives. In all cases, existing data policies and security constraints are fully respected. GENESI-DR also gives access to Grid and Cloud computing resources allowing authorized users to run a number of different processing services on the available data. The GENESI-DR

  12. Winston Churchill (1874-1965), Dr Robson Roose, MD Brux, FRCPE (1848-1905) and Dr Joseph Rutter, MD Lond, MRCP (1834-1913): Treatment for pneumonia in March 1886.

    PubMed

    Vale, J Allister; Scadding, John W

    2018-01-01

    This paper will review Winston Churchill's severe respiratory illness in March 1886 when he developed pneumonia of the right lung as an 11-year-old boy. Winston was treated supportively with 'nourishment, stimulants [probably alcohol] and close watching' at his school by the 'celebrated' family physician, Dr Robson Roose, with the assistance of Dr Joseph Rutter. Roose was exemplary in his commitment to his young patient and assiduous in informing Lord Randolph Churchill of his son's clinical progress by letter.

  13. Treatment with agonistic DR3 antibody results in expansion of donor Tregs and reduced graft-versus-host disease

    PubMed Central

    Kim, Byung-Su; Nishikii, Hidekazu; Baker, Jeanette; Pierini, Antonio; Schneidawind, Dominik; Pan, Yuqiong; Beilhack, Andreas; Park, Chung-Gyu

    2015-01-01

    The paucity of regulatory T cells (Tregs) limits clinical translation to control aberrant immune reactions including graft-versus-host disease (GVHD). Recent studies showed that the agonistic antibody to DR3 (αDR3) expanded CD4+FoxP3+ Tregs in vivo. We investigated whether treating donor mice with a single dose of αDR3 could alleviate acute GVHD in a MHC-mismatched bone marrow transplantation model. αDR3 induced selective proliferation of functional Tregs. CD4+ T cells isolated from αDR3-treated mice contained higher numbers of Tregs and were less proliferative to allogeneic stimuli. In vivo GVHD studies confirmed that Tregs from αDR3-treated donors expanded robustly and higher frequencies of Tregs within donor CD4+ T cells were maintained, resulting in improved survival. Conventional T cells derived from αDR3-treated donors showed reduced activation and proliferation. Serum levels of proinflammatory cytokines (IFNγ, IL-1β, and TNFα) and infiltration of donor T cells into GVHD target tissues (gastrointestinal tract and liver) were decreased. T cells from αDR3-treated donors retained graft-vs-tumor (GVT) effects. In conclusion, a single dose of αDR3 alleviates acute GVHD while preserving GVT effects by selectively expanding and maintaining donor Tregs. This novel strategy will facilitate the clinical application of Treg-based therapies. PMID:26063163

  14. MTB-DR-RIF 9G test: Detection and discrimination of tuberculosis and multi-drug resistant tuberculosis strains.

    PubMed

    Song, Keum-Soo; Nimse, Satish Balasaheb; Cho, Nam Hoon; Sung, Nackmoon; Kim, Hee-Jin; Yang, Jeongseong; Kim, Taisun

    2015-12-01

    This report describes the evaluation of the novel MTB-DR-RIF 9G test for the accurate detection and discrimination of Mycobacterium tuberculosis (MTB) and rifampicin-resistant M. tuberculosis (MTB-DR-RIF) in the clinical samples. The procedure included the amplification of a nucleotide fragment of the rpoB gene of the MTB and MTB-DR-RIF strains and their hybridization with the immobilized probes. The MTB-DR-RIF 9G test was evaluated for its ability to detect and discriminate MTB and MTB-DR-RIF strains in 113 known clinical samples. The accuracy of the MTB-DR-RIF 9G test was determined by comparing its results with sequencing analysis and drug susceptibility testing. The sensitivity and specificity of the MTB-DR-RIF 9G test at 95% confidence interval were found to be 95.4% (89.5-98.5) and 100% (69.2-100), respectively. The positive predictive value and negative predictive value of the MTB-DR-RIF 9G test at 95% confidence interval were found to be 100% (85.0-95.9) and 66.7% (38.4-88.18), respectively. Sequencing analysis of all samples indicated that the mutations present in the regions identified with the MTB-DR-RIF 9G assay can be detected accurately. Copyright © 2015 Elsevier Ltd. All rights reserved.

  15. Dr. Garry Latham - Seismometer Tracings Study - Moon - MSC

    NASA Image and Video Library

    1969-07-22

    S69-39588 (20 July 1969) --- Dr. Garry Latham, with the Lamont Geological Observatory, studies seismometer tracings in the Mission Control Center?s ASEP control room. The electronic data was coming from the Passive Seismic Experiments Package which the Apollo 11 astronauts had just deployed on the surface of the moon. Dr. Lamont is the principal investigator for the PSEP, a component of the Early Apollo Scientific Experiments Package (EASEP). PSEP uses three long-period seismometers and one short-period vertical seismometer for measuring meteoroid impacts and moonquakes. Such data will be useful in determining the interior structure of the moon; for example, does the moon have a core and mantle like Earth? Here, the center trace shows evidence of activity on the moon. The PSEP was sensitive enough to pick up the footsteps of astronauts Neil A. Armstrong and Edwin E. Aldrin Jr. as they walked on the moon.

  16. Gaia DR2 documentation Chapter 6: Spectroscopy

    NASA Astrophysics Data System (ADS)

    Sartoretti, P.; Blomme, R.; David, M.; Seabroke, G.

    2018-04-01

    This chapter of the Gaia DR2 documentation describes the processing and validation of the Radial Velocity Spectrometer (RVS) data. A more detailed description of the processing is provided in Sartoretti et al. (2018) and of the validation in Katz et al. (2018). A description of the RVS instrument is provided in Cropper et al. (2018).

  17. Seafloor tilt induced by ocean tidal loading inferred from broadband seismometer data from the Cascadia subduction zone and Juan de Fuca Ridge

    NASA Astrophysics Data System (ADS)

    Davis, Earl E.; Heesemann, Martin; Lambert, Anthony; He, Jianheng

    2017-04-01

    Mass-balancing voltages from four buried broadband seismometers connected to the NEPTUNE Canada seafloor cable are being recorded at 24-bit resolution. Sites are located on the Vancouver Island continental shelf, the nearby Cascadia accretionary prism, the eastern flank of the Juan de Fuca Ridge, and the western flank close to the Juan de Fuca Ridge axis. Tidal variations are present throughout the records. Variations in vertical acceleration at three of the sites match predicted gravitational attraction variations very well; those at the fourth site show a small residual that is probably caused by sensitivity to tilt resulting from sensor inclination. Horizontal accelerations, which at tidal periods are sensitive primarily to tilt, are anomalously large relative to standard-earth model results. After removal of predicted tidal body and ocean attraction and loading terms, the residuals are seen to follow ocean pressure variations. Responses range from 0.4 μrad dbar-1 (0.04 μrad kPa-1) at 10° true (down under positive load) at the continental shelf site, to 0.6 μrad dbar-1 at 243° at the Cascadia prism, 0.4 μrad dbar-1 at 90° at the eastern Juan de Fuca Ridge flank, and 0.2 μrad dbar-1 at 116° true on the western ridge flank. Except at the continental shelf site, tilts are roughly perpendicular to structural strike. The tilt observations can be explained by loading-induced deformation in the presence of local lithologic gradients or by the influence of faults or structurally controlled anisotropic elastic properties. The observations highlight the utility of using mass position data from force-feedback broad-band seismometers for geodynamic studies.

  18. Ask Dr. Sue--Updates: Infectious Diseases, SIDS, HIV/AIDS.

    ERIC Educational Resources Information Center

    Aronson, Susan S.

    1995-01-01

    Describes new concerns about infectious diseases in childcare settings (tuberculosis, gastrointestinal infections, and lice); sleep position and SIDS; HIV/AIDS issues; and the use of sterilized sand in sand boxes. (DR)

  19. [Dr. Moshe Sherman--the first otolaryngologist in Eretz-Israel: 100 years since his arrival].

    PubMed

    Golz, Avishay; Netzer, Aviram

    2012-01-01

    On 4.8.1911 Dr. Moshe Sherman landed at the port of Jaffa. He was the first otolaryngologist in Eretz-Israel and for one year he was the only specialist in the country. Dr. Sherman was born in Nikolayev (Russia) in 1881. He started his medical education in Odessa, continued in Berlin, graduated in 1907 at the University of Dorpat (Estonia) and pursued postgraduate studies in otolaryngology at Moscow University. He settled in Jaffa, started a private practice and soon became a famous specialist. He volunteered at the Jewish hospital in Jaffa--"Shaar Zion", and twice a year spent several weeks in Jerusalem seeing patients and performing small operations. On January 1912 Dr. Sherman, together with another 5 physicians, laid the foundations for the first doctors' organization in Israel: "The Medical Society of Jaffa and Jaffa district". In 1918 Dr. Sherman was elected consultant at the Hadassah Hospital in Tel Aviv, and in 1932 a department for ear, nose and throat diseases was established there under his management. He was the founder and first chairman of the Ototaryngology Society in Eretz-Israel, and in 1935 was elected the chairman of the Jewish Medical Association in Eretz-Israel (later--its honorary president). He was the initiator and founder of the "World Fellowship", and the Editor in Chief of 'Harefuah' and "Michtav Lachaver". Dr. Sherman was the author of numerous papers related to his specialty and to the history of Jewish organizations in Eretz-Israel and, later, in the State of Israel. Dr. Sherman died in Tel Aviv on July 17th 1969.

  20. HLA-DR4 as a risk allele for autism acting in mothers of probands possibly during pregnancy.

    PubMed

    Johnson, William G; Buyske, Steven; Mars, Audrey E; Sreenath, Madhura; Stenroos, Edward S; Williams, Tanishia A; Stein, Rosanne; Lambert, George H

    2009-06-01

    To test whether HLA-DR4 acts in the mother, possibly during pregnancy, to contribute to the phenotype of autistic disorder in her fetus. Transmission disequilibrium testing in case mothers and maternal grandparents. Previous studies have consistently shown increased frequency of HLA-DR4 in probands with autism and their mothers, but not their fathers. However, this has been documented only in case-control studies and not by a more direct study design to determine whether HLA-DR4 acts in mothers during pregnancy to contribute to autism in their affected offspring. We genotyped for HLA-DR alleles in members of 31 families with parents and maternal grandparents. Probands with autism were tested using the Autism Diagnostic Observation Schedule-Western Psychological Services and Autism Diagnostic Interview, Revised. There was 80% power to detect an odds ratio of 3.6. Participants were all families from New Jersey and were similar in number to earlier studies of autism and HLA-DR4. Analysis was by standard transmission disequilibrium testing. As a secondary test we examined the possibility of maternal imprinting. Significant transmission disequilibrium for HLA-DR4 was seen (odds ratio, 4.67; 95% confidence interval, 1.34-16.24; P = .008) for transmissions from maternal grandparents to mothers of probands, supporting a role for HLA-DR4 as an autism risk factor acting in mothers during pregnancy. Transmission disequilibrium was not seen for HLA-DR4 transmissions from parents to probands or from mothers to probands. The HLA-DR4 gene may act in mothers of children with autism during pregnancy to contribute to autism in their offspring. Further studies are required to confirm these findings.

  1. Association between human leukocyte antigen-DR and demylinating Guillain-Barré syndrome

    PubMed Central

    Hasan, Zaki N.; Zalzala, Haider H.; Mohammedsalih, Hyam R.; Mahdi, Batool M.; Abid, Laheeb A.; Shakir, Zena N.; Fadhel, Maithem J.

    2014-01-01

    Objective: To find an association between human leukocyte antigen (HLA) class II DRB1, DRB3, DRB4, and DRB5 alleles frequencies in a sample of Iraqi patients with Guillain-Barré syndrome (GBS) and compare with a healthy control group. Methods: We performed a cross-sectional study consisting of 30 Iraqi Arab patients with GBS attending the Neurological Department in the Neuroscience Hospital, Baghdad, Iraq between September 2012 and June 2013. The control group comprised 42 apparently healthy volunteers. Human leukocyte antigen genotyping for HLA DRB1, DRB3, DRB4, and DRB5 was performed using the polymerase chain reaction-sequence-specific primers method. The allele frequencies were compared across both groups. Major histocompatibility complex (MHC)-class II HLA-DR genotyping and serotyping were performed by software analysis. Results: We found increased frequencies of HLA genotype DRB1*03:01 (p=0.0009), DRB1*07:01 (p=0.0015), and DRB4*01:01 (p<0.0001) in patients with GBS compared with healthy controls. The HLA DR6 was increased in the control group (p<0.0001). Conclusions: Our results suggest an association between HLA-DRB1*03:01, DRB1*07:01, DRB4*01:01, and HLA DR3, DR7 and a susceptibility to GBS. PMID:25274590

  2. K-ras mutations and HLA-DR expression in large bowel adenomas.

    PubMed Central

    Norheim Andersen, S.; Breivik, J.; Løvig, T.; Meling, G. I.; Gaudernack, G.; Clausen, O. P.; Schjölberg, A.; Fausa, O.; Langmark, F.; Lund, E.; Rognum, T. O.

    1996-01-01

    A total of 72 sporadic colorectal adenomas in 56 patients were studied for the presence of point mutations in codons 12 and 13 of the K-ras gene and for HLA-DR antigen expression related to clinicopathological variables. Forty K-ras mutations in 39 adenomas were found (54%): 31 (77%) in codon 12 and nine (23%) in codon 13. There was a strong relationship between the incidence of K-ras mutations and adenoma type, degree of dysplasia and sex. The highest frequency of K-ras mutations was seen in large adenomas of the villous type with high-grade dysplasia. Fourteen out of 15 adenomas obtained from 14 women above 65 years of age carried mutations. HLA-DR positivity was found in 38% of the adenomas, large tumours and those with high-grade dysplasia having the strongest staining. Coexpression of K-ras mutations and HLA-DR was found significantly more frequently in large and highly dysplastic adenomas, although two-way analysis of variance showing size and grade of dysplasia to be the most important variable. None of the adenomas with low-grade dysplasia showed both K-ras mutation and HLA-DR positivity (P = 0.004). K-ras mutation is recognised as an early event in colorectal carcinogenesis. The mutation might give rise to peptides that may be presented on the tumour cell surface by class II molecules, and thereby induce immune responses against neoplastic cells. Images Figure 3 Figure 4 Figure 5 Figure 6 PMID:8679466

  3. Newborn HLA-DR,DQ genotype screening: age- and ethnicity-specific type 1 diabetes risk estimates

    PubMed Central

    Emery, Lisa M; Babu, Sunanda; Bugawan, Teodorica L; Norris, Jill M; Erlich, Henry A; Eisenbarth, George S; Rewers, Marian

    2005-01-01

    Objective Certain human leukocyte antigen (HLA)-DR,DQ genotypes have been associated with type 1 diabetes mellitus (T1DM) risk, although it is unknown whether the association is due to alleles, haplotypes, genotypes, the formation of heterodimers, or all of the above. To characterize the role of the HLA-DR,DQ genotype and ethnicity on the onset age of T1DM, we analyzed these factors in patients with T1DM and the general population. Methods One thousand three hundred twenty-two well-characterized patients with T1DM were compared with 3339 children from the general population of Denver, Colorado, USA. Because of the extensive available data across age and ethnic groups, this study population is unique. Results The HLA-DR3/4,DQB1*0302, DRX/4,DQB1*0302 (where X = 1, 4, 8, and 9), and HLA-DR3/3 genotypes were associated with T1DM, supporting previous research. Additionally, the DR3/9 genotype showed a positive association with T1DM, which has not previously been described in Caucasian populations. The HLA-DR3/4*0302 genotype was most strongly associated with T1DM in diabetic individuals with the youngest onset age. Genotype frequencies were similar between Hispanics and non-Hispanic whites, except for the DR3/3 genotype, which was more likely to be found in non-Hispanic whites. Conclusions These results indicate that there are multiple alleles and genotypes associated with T1DM and that the risk associated with different genetic markers depends on the age of disease onset, suggesting that some markers may be involved in more rapid disease progression. PMID:16109069

  4. [Study on correlation between HLA-A, B, DR alleles and Duchenne muscular dystrophy].

    PubMed

    Chen, Wei; Xiao, Lulu; Zhang, Cheng; Wu, Hong-ling

    2007-10-01

    To analyze the polymorphism of HLA-A, B and DR alleles of Duchenne muscular dystrophy (DMD) patients in Han nationality of South China and to discuss the role of immune and genetic factors in the pathogenesis of DMD and muscular fiber necrosis. Polymerase chain reaction-reverse sequence specific oligonucleotide (PCR-RSSO) and National Marrow Donor Program (NMDP) were used to analyze the polymorphism of HLA-A,B and DR alleles of 113 DMD patients and 406 normal controls in Han nationality of South China. The frequencies of HLA-A24, A30 alleles in DMD group were 11.25% and 5.46% respectively, indicating notable difference (P=0.001, < 0.01) from 22.16% and 0.87% of control group; the frequencies of HLA-B13, B15, B61 and B62 alleles in DMD group were 12.26%, 16.92%, 0.44% and 0.44%, indicating a notable difference (P=0.016, < 0.01, 0.001) from 6.76%, 1.49%, 4.79% and 5.05% of control group; the frequencies of HLA-DR04, DR07, DR12 alleles in DMD group were 17.45%, 6.40% and 19.62%, indicating a notable difference (P=0.018, < 0.01, 0.012) from 10.67%, 2.24% and 11.92% of control group. There are significant differences in the HLA gene frequencies between DMD patients and normal controls. These results suggest that HLA genotype relates to the muscular necrosis and the pathogenesis of DMD.

  5. Steganography: LSB Methodology

    DTIC Science & Technology

    2012-08-02

    images ; LSB Embedding Angel Sierra, Dr. Alfredo Cruz (Advisor) Polytechnic University of Puerto Rico 377 Ponce De Leon Hato Rey San Juan, PR 00918...notepad document as the message input. - Reviewed the battlesteg algorithm java code. POLYTECHNIC UNIVERSITY OF PUERTO RICO Steganography : LSB ...of LSB steganography in grayscale and color images . In J. Dittmann, K. Nahrstedt, and P. Wohlmacher, editors, Proceedings of the ACM, Special

  6. Dr John McLennan MD (Aberdeen), FRCP (Lond) (1801-1874) and the Medical School of Bombay that failed.

    PubMed

    Pandya, Sunil K

    2017-01-01

    In 1826, Dr John McLennan was asked by Governor Mounstuart Elphinstone of Bombay to set up the first school to teach modern medicine to Indian citizens. He was expected to create textbooks on a variety of subjects in local languages and teach medicine to poorly educated students in their native tongues. Despite his valiant efforts, the school was deemed a failure and was abolished by the Government in 1832. Sir Robert Grant, appointed Governor of Bombay in 1835, analysed records pertaining to this medical school and concluded that the school failed since Dr McLennan was not provided the assistance he needed and as his suggestions for access to a hospital to teach medicine were not heeded. Dr McLennan provided able support to Dr Charles Morehead on his appointment as Principal and Professor of Medicine at the newly created Grant Medical College in Bombay in 1845. Dr Morehead dedicated his classic 'Clinical researches on diseases in India' to Dr McLennan. Dr McLennan headed the Board of Examiners created to assess the competence of the first batch of medical students emerging from this College. The system of evaluation set up by him remains admirable. Dr McLennan retired from service as Physician-General, full of honours.

  7. First inventory of the Crustacea (Decapoda, Stomatopoda) of Juan de Nova Island with ecological observations and comparison with nearby islands in the Mozambique channel (Europa, Glorieuses, Mayotte)

    NASA Astrophysics Data System (ADS)

    Poupin, J.

    2016-04-01

    Crustacea Decapoda and Stomatopoda are inventoried for the first time in Juan de Nova Island, Iles Eparses, Mozambique channel. In total, 112 species are reported: 69 crabs, 28 anomurans, 11 shrimps, 3 mantis shrimps and 1 lobster. A comparison is made with nearby islands in the Mozambique channel: Glorieuses Islands (157 species), Europa Island (178 species), and Mayotte Island (505 species). The lower species richness at Juan de Nova is explained by the small size of the island and by the difficulties to collect the crustaceans on the reef flat hardly accessible at low tide. The crustaceans are listed by main habitats from land to outer reef (2-20 m). The presence of the coconut crab (Birgus latro), an endangered species vulnerable to human predation, is confirmed.

  8. Simpler and equitable allocation of kidneys from postmortem donors primarily based on full HLA-DR compatibility.

    PubMed

    Doxiadis, Ilias I N; de Fijter, Johan W; Mallat, Marko J K; Haasnoot, Geert W; Ringers, Jan; Persijn, Guido G; Claas, Frans H J

    2007-05-15

    The introduction of human leukocyte antigen (HLA)-matching in nonliving kidney transplantation has resulted into a better graft outcome, but also in an increase of waiting time, especially for patients with rare HLA phenotypes. We addressed the question of the differential influence of HLA-DR-matching versus HLA-A,B in clinical kidney transplantation. We used Kaplan-Meier product limit method to estimate survival rates, and Cox proportional hazard regression for the estimation of relative risks (Hazard-ratios) for different variables. A single center study (n=456 transplants, performed between 1985 and 1999) showed that full HLA-DR compatibility leads to a lower incidence of biopsy confirmed acute rejections in the first 180 posttransplantation days. These results were substantiated using the Eurotransplant database (n=39,205 transplants performed between 1985 and 2005) where graft survival in the full HLA-DR compatible group was significantly better than in the incompatible. An additional positive effect of HLA-A,B matching was only found in the full HLA-DR compatible group. In both studies, the introduction of a single HLA-DR incompatibility eliminates the HLA-A,B matching effect. We propose to allocate postmortem kidneys only to patients with full HLA-DR compatibility, and use HLA-A,B compatibility as an additional selection criterion. All patients, irrespective of their ethnic origin, will profit since the polymorphism of HLA-DR is by far lower than that of HLA-A,B. Excessive kidney travel and cold ischemia time will be significantly reduced.

  9. Gordon Research Conference on Chronobiology

    DTIC Science & Technology

    1993-11-01

    AMHERST MA 01002 DR ANTONI DIEZ-NOGUERA OFF UNIVERSITY OF BARCELONA 3434907869 LABORATORY DE FISIOLOGIA ATTENDEE FACULTAT 03 FARMACIA, AV JOAN XXIII SIN...WALTHAM MA 02254 DR BEATRIZ FUENTES-PARDO P 303 UNIV. NACIONAL AUTONOMA DE MEXICO 525-623-2362 DEPARTAMENTO DE FISIOLOGIA , FAC. DE KED. ATTENDEE APDO...Vilaplana, T.Cambras (Laboratori de Fisiologia , Facultat de Farmacia, Universitat de Barcelona): Effects of period length of light/dark cycles in the

  10. [The American bacteriologist: Dr. Meyer].

    PubMed

    Li, Zheng; Li, Zhi-ping

    2009-01-01

    Karl F. Meyer who was born in Switzerland was American famous bacteriologist of 20th century. During the World War II, Dr. Meyer urged the U. S. military to take positive reply measures against the bacteria war started by Japanese army and achieved significant accomplishments in the preventive and therapeutic theory of plague as well as the manufacture of plague vaccine. After the World War II, Meyer devoted to the scientific field of plague prevention and made great achievements in the area of animal diseases and public health. In 1951, he received the Lasker Award of America.

  11. The great neurosis of Dr. Joseph Gerard.

    PubMed

    Lefrère, Jean-Jacques; Rouillon, Frédéric

    2013-01-01

    The Great Neurosis, of Dr. Joseph Gerard, was published in 1889 in Paris. The book, intended for the general public, shows the different varieties of neuroses through picturesque and instructive examples. Its scientific and medical value is poor, but provides us with the various meanings of the word 'neurosis' in the late nineteenth century. Copyright © 2013 S. Karger AG, Basel.

  12. Gaia DR2 documentation Chapter 1: Introduction

    NASA Astrophysics Data System (ADS)

    de Bruijne, J. H. J.; Abreu, A.; Brown, A. G. A.; Castañeda, J.; Cheek, N.; Crowley, C.; De Angeli, F.; Drimmel, R.; Fabricius, C.; Fleitas, J.; Gracia-Abril, G.; Guerra, R.; Hutton, A.; Messineo, R.; Mora, A.; Nienartowicz, K.; Panem, C.; Siddiqui, H.

    2018-04-01

    This chapter of the Gaia DR2 documentation describes the Gaia mission, the Gaia spacecraft, and the organisation of the Gaia Data Processing and Analysis Consortium (DPAC), which is responsible for the processing and analysis of the Gaia data. Furthermore, various properties of the data release are summarised, including statistical properties, object statistics, completeness, selection and filtering criteria, and limitations of the data.

  13. Final report, PT IP-535-C: Test of smaller VSR`s in DR reactor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vaughn, A.D.

    1963-04-17

    Because of rod-sticking problems at DR Reactor, a knuckle rod of B Reactor design was installed in vertical safety channel number 28. The substitute VSR, which has a smaller diameter than the original DR rod, has been tested for its operational feasibility including both drop time and reactivity effect. The reactivity effect of the rod was estimated by comparison of the reactivity transient caused by insertion of the specific B-type rod after scramming into the pile, with similar transients caused by normal vertical safety rod in an adjacent channel. This document lists the indicated relative control strength of the rodmore » as an empirical basis for future safety calculations. Results indicate that the B-type knuckel rod in DR reactor is about 80% as strong as a normal DR vertical safety rod if used in equivalent flux distribution and location; this makes it reasonable to assume that the local control strength of the B-type knuckel rod is 98 {mu}b.« less

  14. Establishment of HLA-DR4 Transgenic Mice for the Identification of CD4+ T Cell Epitopes of Tumor-Associated Antigens

    PubMed Central

    Harada, Kumiko; Michibata, Yayoi; Tsukamoto, Hirotake; Senju, Satoru; Tomita, Yusuke; Yuno, Akira; Hirayama, Masatoshi; Abu Sayem, Mohammad; Takeda, Naoki; Shibuya, Isao; Sogo, Shinji; Fujiki, Fumihiro; Sugiyama, Haruo; Eto, Masatoshi; Nishimura, Yasuharu

    2013-01-01

    Reports have shown that activation of tumor-specific CD4+ helper T (Th) cells is crucial for effective anti-tumor immunity and identification of Th-cell epitopes is critical for peptide vaccine-based cancer immunotherapy. Although computer algorithms are available to predict peptides with high binding affinity to a specific HLA class II molecule, the ability of those peptides to induce Th-cell responses must be evaluated. We have established HLA-DR4 (HLA-DRA*01:01/HLA-DRB1*04:05) transgenic mice (Tgm), since this HLA-DR allele is most frequent (13.6%) in Japanese population, to evaluate HLA-DR4-restricted Th-cell responses to tumor-associated antigen (TAA)-derived peptides predicted to bind to HLA-DR4. To avoid weak binding between mouse CD4 and HLA-DR4, Tgm were designed to express chimeric HLA-DR4/I-Ed, where I-Ed α1 and β1 domains were replaced with those from HLA-DR4. Th cells isolated from Tgm immunized with adjuvant and HLA-DR4-binding cytomegalovirus-derived peptide proliferated when stimulated with peptide-pulsed HLA-DR4-transduced mouse L cells, indicating chimeric HLA-DR4/I-Ed has equivalent antigen presenting capacity to HLA-DR4. Immunization with CDCA155-78 peptide, a computer algorithm-predicted HLA-DR4-binding peptide derived from TAA CDCA1, successfully induced Th-cell responses in Tgm, while immunization of HLA-DR4-binding Wilms' tumor 1 antigen-derived peptide with identical amino acid sequence to mouse ortholog failed. This was overcome by using peptide-pulsed syngeneic bone marrow-derived dendritic cells (BM-DC) followed by immunization with peptide/CFA booster. BM-DC-based immunization of KIF20A494-517 peptide from another TAA KIF20A, with an almost identical HLA-binding core amino acid sequence to mouse ortholog, successfully induced Th-cell responses in Tgm. Notably, both CDCA155-78 and KIF20A494-517 peptides induced human Th-cell responses in PBMCs from HLA-DR4-positive donors. Finally, an HLA-DR4 binding DEPDC1191-213 peptide from a new

  15. Life story of Dr. Hulusi Behçet.

    PubMed

    Saylan, T

    1997-12-01

    Dr. Hulusi Behçet was born on February 20, 1889 in Istanbul. He graduated from Gülhane Military Medical Academy in 1910 and then he specialized in Dermatology and Venereal Diseases. He served in the Edirne Military Hospital between 1914-1918 and then went to Budapest and Berlin to improve his knowledge. In 1923, he started at the Istanbul Medical Faculty as an academic staff and with university reform in 1933, he was appointed as a professor to Department of Dermatology and Venereal Diseases and continued his career there until his death in 1948. Three patients whom he had consulted for years and who shared similar symptoms made him suspect a new disease and a viral etiology which may play a role in the appearance of this disease. After several discussions and publications, medical literature had accepted Behçet's Disease as a special entity. Dr. Behçet published a total of 196 articles, 53 of which were published in prestigious international journals.

  16. Brine formation via deliquescence by salts found near Don Juan Pond, Antarctica: Laboratory experiments and field observational results

    NASA Astrophysics Data System (ADS)

    Gough, R. V.; Wong, J.; Dickson, J. L.; Levy, J. S.; Head, J. W.; Marchant, D. R.; Tolbert, M. A.

    2017-10-01

    The observed darkening of water tracks near Don Juan Pond (DJP) as well as the formation of wet patches elsewhere in the McMurdo Dry Valleys is attributed at least partially to deliquescence, a process by which salts absorb atmospheric water vapor and form brine, coupled with liquid-phase growth when the atmospheric relative humidity exceeds the water activity. Here we perform laboratory experiments to investigate the temperature and relative humidity conditions necessary for deliquescence to occur in calcium chloride-rich sediments collected from the DJP watershed. We use a Raman microscope equipped with an environmental cell to study both deliquescence and efflorescence (recrystallization) of the soluble salt component of DJP soils between -30 and +15 °C. In this temperature range, we find that the soluble salt component of the DJP sediments begins to deliquesce between 19 and 46% RH, slightly higher than the deliquescence relative humidity of the primary pure component, calcium chloride. We find a limited hysteresis between deliquescence and efflorescence, but much greater supersaturation of the salt brine can occur at temperatures above 0 °C. The relative humidity conditions were varied either slowly (over ∼8 h) to observe near-equilibrium phases or rapidly (over <1 h) to better mimic Antarctic conditions and no differences in deliquescence relative humidity or efflorescence relative humidity were noted. The results of this work can help predict when deliquescence could be actively occurring in the soils near Don Juan Pond and explain darkening of the salt pan after a high humidity period. In tandem with field data, our experimental results suggest that brines can be generated near Don Juan Pond via deliquescence frequently during the southern summer and autumn. Additionally, the soluble salts may persist in the aqueous phase continuously for several months during the southern summer. This work also suggests that salt deliquescence could be impacting the

  17. The induction of autoimmune hepatitis in the human leucocyte antigen‐DR4 non‐obese diabetic mice autoimmune hepatitis mouse model

    PubMed Central

    Yuksel, M.; Xiao, X.; Tai, N.; Vijay, G. M.; Gülden, E.; Beland, K.; Lapierre, P.; Alvarez, F.; Hu, Z.; Colle, I.; Ma, Y.

    2016-01-01

    Summary Autoimmune hepatitis (AIH) is a chronic liver disease characterized by progressive inflammation, female preponderance and seropositivity for autoantibodies such as anti‐smooth muscle actin and/or anti‐nuclear, anti‐liver kidney microsomal type 1 (anti‐LKM1) and anti‐liver cytosol type 1 (anti‐LC1) in more than 80% of cases. AIH is linked strongly to several major histocompatibility complex (MHC) alleles, including human leucocyte antigen (HLA)‐DR3, ‐DR7 and ‐DR13. HLA‐DR4 has the second strongest association with adult AIH, after HLA‐DR3. We investigated the role of HLA‐DR4 in the development of AIH by immunization of HLA‐DR4 (DR4) transgenic non‐obese diabetic (NOD) mice with DNA coding for human CYP2D6/FTCD fusion autoantigen. Immunization of DR4 mice leads to sustained mild liver injury, as assessed biochemically by elevated alanine aminotransferase, histologically by interface hepatitis, plasma cell infiltration and mild fibrosis and immunologically by the development of anti‐LKM1/anti‐LC1 antibodies. In addition, livers from DR4 mice had fewer regulatory T cells (Tregs), which had decreased programmed death (PD)‐1 expression. Splenic Tregs from these mice also showed impaired inhibitory capacity. Furthermore, DR4 expression enhanced the activation status of CD8+ T cells, macrophages and dendritic cells in naive DR4 mice compared to naive wild‐type (WT) NOD mice. Our results demonstrate that HLA‐DR4 is a susceptibility factor for the development of AIH. Impaired suppressive function of Tregs and reduced PD‐1 expression may result in spontaneous activation of key immune cell subsets, such as antigen‐presenting cells and CD8+ T effectors, facilitating the induction of AIH and persistent liver damage. PMID:27414259

  18. The induction of autoimmune hepatitis in the human leucocyte antigen-DR4 non-obese diabetic mice autoimmune hepatitis mouse model.

    PubMed

    Yuksel, M; Xiao, X; Tai, N; Vijay, G M; Gülden, E; Beland, K; Lapierre, P; Alvarez, F; Hu, Z; Colle, I; Ma, Y; Wen, L

    2016-11-01

    Autoimmune hepatitis (AIH) is a chronic liver disease characterized by progressive inflammation, female preponderance and seropositivity for autoantibodies such as anti-smooth muscle actin and/or anti-nuclear, anti-liver kidney microsomal type 1 (anti-LKM1) and anti-liver cytosol type 1 (anti-LC1) in more than 80% of cases. AIH is linked strongly to several major histocompatibility complex (MHC) alleles, including human leucocyte antigen (HLA)-DR3, -DR7 and -DR13. HLA-DR4 has the second strongest association with adult AIH, after HLA-DR3. We investigated the role of HLA-DR4 in the development of AIH by immunization of HLA-DR4 (DR4) transgenic non-obese diabetic (NOD) mice with DNA coding for human CYP2D6/FTCD fusion autoantigen. Immunization of DR4 mice leads to sustained mild liver injury, as assessed biochemically by elevated alanine aminotransferase, histologically by interface hepatitis, plasma cell infiltration and mild fibrosis and immunologically by the development of anti-LKM1/anti-LC1 antibodies. In addition, livers from DR4 mice had fewer regulatory T cells (T regs ), which had decreased programmed death (PD)-1 expression. Splenic T regs from these mice also showed impaired inhibitory capacity. Furthermore, DR4 expression enhanced the activation status of CD8 + T cells, macrophages and dendritic cells in naive DR4 mice compared to naive wild-type (WT) NOD mice. Our results demonstrate that HLA-DR4 is a susceptibility factor for the development of AIH. Impaired suppressive function of T regs and reduced PD-1 expression may result in spontaneous activation of key immune cell subsets, such as antigen-presenting cells and CD8 + T effectors, facilitating the induction of AIH and persistent liver damage. © 2016 British Society for Immunology.

  19. HLA-DR2-associated DRB1 and DRB5 alleles and haplotypes in Koreans.

    PubMed

    Song, E Y; Kang, S J; Lee, Y J; Park, M H

    2000-09-01

    There are considerable racial differences in the distribution of HLA-DR2-associated DRB1 and DRB5 alleles and the characteristics of linkage disequilibrium between these alleles. In this study, the frequencies of DR2-associated DRB1 and DRB5 alleles and related haplotypes were analyzed in 186 DR2-positive individuals out of 800 normal Koreans registered for unrelated bone marrow donors. HLA class I antigen typing was performed by the serological method and DRB1 and DRB5 genotyping by the PCR-single strand conformational polymorphism method. Only 3 alleles were detected for DR2-associated DRB1 and DRB5 genes, respectively: DRB1(*)1501 (gene frequency 8.0%), (*)1502 (3.2%), (*)1602 (0.9%); DRB5(*)0101 (8.0%), (*)0102 (3.2%), and (*)0202 (0.9%). DRB1-DRB5 haplotype analysis showed an exclusive association between these alleles: DRB1*1501-DRB5*0101 (haplotype frequency 8.0%), DRB1(*)1502-DRB5(*)0102 (3.2%), and DRB1(*)1602-DRB5(*)0202 (0.9%). The 5 most common DR2-associated A-B-DRB1 haplotypes occurring at frequencies of > or = 0.5% were A24-B52-DRB1(*)1502 (1.8%), A2-B62-DRB1(*)1501, A2-B54-DRB1(*)1501, A26-B61-DRB1(*)1501, and A24-B51-DRB1(*)1501. The remarkable homogeneity in the haplotypic associations between DR2-associated DRB1 and DRB5 alleles in Koreans would be advantageous for organ transplantation compared with other ethnic groups showing considerable heterogeneity in the distribution of DRB1-DRB5 haplotypes.

  20. Dr. Chad E. Finn, 2013 Wilder Medal Recipient

    USDA-ARS?s Scientific Manuscript database

    Dr. Chad Finn took over the leadership of the USDA-ARS small fruit breeding program in Corvallis, Oregon in 1993 after three years working as an extension horticulturist in the Department of Horticulture at the University of Missouri, Columbia. Since taking over this program he has developed what is...

  1. The life and legacy of Dr. Lee Baldwin

    USDA-ARS?s Scientific Manuscript database

    This paper outlines the life and legacy of the late Dr. Ransom L. Baldwin, V. The purpose was to highlight the impact his teaching and research had on the international energy and protein metabolism communities at their fourth international conference. The paper will be presented at the outset of ...

  2. Of Brain and Bone: The Unusual Case of Dr. A

    PubMed Central

    Narvid, J; Gorno-Tempini, ML; Slavotinek, A; DeArmond, SJ; Cha, YH; Miller, BL; Rankin, K.P

    2009-01-01

    Frontotemporal dementia (FTD) is a clinical syndrome characterized by progressive decline in social conduct and a focal pattern of frontal and temporal lobe damage. Its biological basis is still poorly understood but the focality of the brain degeneration provides a powerful model to study the cognitive and anatomical basis of social cognition. Here, we present Dr. A, a patient with a rare hereditary bone disease (hereditary multiple exostoses) and FTD (pathologically characterized as Pick’s disease), who presented with a profound behavioral disturbance characterized by acquired sociopathy. We conducted a detailed genetic, pathological, neuroimaging and cognitive study, including a battery of tests designed to investigate Dr. A’s abilities to understand emotional cues and to infer mental states and intentions to others (theory of mind). Dr. A’s genetic profile suggests the possibility that a mutation causing hereditary multiple exostoses, Ext2, may play a role in the pattern of neurodegeneration in frontotemporal dementia since knockout mice deficient in the Ext gene family member, Ext1, show severe CNS defects including loss of olfactory bulbs and abnormally small cerebral cortex. Dr. A showed significant impairment in emotion comprehension, second order theory of mind, attribution of intentions, and empathy despite preserved general cognitive abilities. Voxel-based morphometry on structural MRI images showed significant atrophy in the medial and right orbital frontal and anterior temporal regions with sparing of dorsolateral frontal cortex. This case demonstrates that social and emotional dysfunction in FTD can dissociate from preserved performance on classic executive functioning tasks. The specific pattern of anatomical damage shown by VBM emphasizes the importance of the network including the superior medial frontal gyrus as well as temporal polar areas, in regulation of social cognition and theory of mind. This case provides new evidence regarding the

  3. [Dr. Moritz Wallach--a century of medicine and tradition in Shaare Zedek].

    PubMed

    Navot, Orit

    2003-06-01

    Dr. Wallach, who founded the Shaare Zedek Hospital and managed the institution for forty-five years, was instrumental in providing modern medical care to Jerusalem residents since his arrival in the city in 1891. He dedicated his life to medicine, to the Jerusalem Jewish community, and to improving the quality of service provided by the existing medical establishment. He was one of the outstanding personalities in a city and community struggling for existence. The Jewish religious character that marks today's Shaare Zedek hospital was determined 100 years ago by Dr. Wallach, who integrated the ancient Jewish moral spirit into a modern medical service tradition. While fulfilling his daily tasks, both as a practicing physician and as the hospital-director, Dr. Wallach became a role model to those who followed him. He mixed freely with the "elite" and his personal relations with local dignitaries, political figures, influential westerners, intellectuals, and important foreign diplomats contributed significantly to the growth, success, and reputation the hospital enjoyed during the last century. On the other hand, he was also personally involved with destitute new immigrants to Eretz Israel and actively engaged in finding jobs, housing, and employment for them. Dr. Wallach became a legend in his own time, both locally and internationally. Due to his professional status and personality, Dr. Wallach became a representative of the Jewish community. He had the ability to speak for the Jews with the Ottoman authorities, and afterwards with the British Mandate authorities. He played a significant role in educating the population in public responsibility, while concurrently leaving his mark on generations of physicians who learned from him the value of precision, loyalty, professional secrecy, and medical responsibility. He was one of the "Giants" of the land (Yishuv) in its critical formative years.

  4. Principles of plastic surgery portrayed by the professional life of Dr John Peter Mettauer.

    PubMed

    Avashia, Yash J; Thaller, Seth R

    2011-11-01

    Regarded as "America's first plastic surgeon," Dr John Peter Mettauer's professional life displays 3 fundamental keystones of plastic surgery: education, innovation, and practice. To fully appreciate the history of our plastic surgery, one must look beyond a purely factual recount of noteworthy actions performed decades ago. Fundamental principles that governed achievements of our predecessors remain applicable even today. Dr Mettauer thrived as a medical student under the influence of distinguished professors in medicine at the University of Pennsylvania. Later, he continued to propagate their basic tenets when he established his medical institute in 1837. Throughout his life, Dr Mettauer combined ingenuity with scientific inquiry to devise numerous unprecedented surgical techniques and instruments. He was a prolific writer and exquisitely documented his work in medical journals for the benefit of both contemporary and future surgeons. One of Dr Mettauer's momentous achievements in plastic surgery that displays his remarkable capabilities was his contributions to management of both simple and complicated cases of cleft palate. He was the first to describe relaxing lateral incisions for treating complete cleft palates and, incidentally, was the first to successfully treat this in America. He invariably replicated similar success in establishing techniques for treating a wide range of anatomic deformities. Cumulatively, Dr Mettauer's lifelong commitment and diligence have truly laid a foundation for the eventual progress and success in the field of plastic surgery.

  5. U, Th, and Pb isotopes in hot springs on the Juan de Fuca Ridge

    NASA Technical Reports Server (NTRS)

    Chen, J. H.

    1987-01-01

    Concentrations and isotopic compositions of U, Th, and Pb in three hydrothermal fluids from the Juan de Fuca Ridge were determined from samples obtained by the Alvin submersible. The samples were enriched in Pb and Th relative to deep-sea water, and were deficient in U. No clear relationship with Mg was found, suggesting nonideal mixing between the hot hydrothermal fluids and the cold ambient seawater. Values for U-234/U-238 have a seawater signature, and show a U-234 enrichment relative to the equilibrium value. The Pb isotopic composition has a uniform midocean ridge basalt signature, and it is suggested that Pb in these fluids may represent the best average value of the local oceanic crust.

  6. San Juan National Forest Land Management Planning Support System (LMPSS) requirements definition

    NASA Technical Reports Server (NTRS)

    Werth, L. F. (Principal Investigator)

    1981-01-01

    The role of remote sensing data as it relates to a three-component land management planning system (geographic information, data base management, and planning model) can be understood only when user requirements are known. Personnel at the San Juan National Forest in southwestern Colorado were interviewed to determine data needs for managing and monitoring timber, rangelands, wildlife, fisheries, soils, water, geology and recreation facilities. While all the information required for land management planning cannot be obtained using remote sensing techniques, valuable information can be provided for the geographic information system. A wide range of sensors such as small and large format cameras, synthetic aperture radar, and LANDSAT data should be utilized. Because of the detail and accuracy required, high altitude color infrared photography should serve as the baseline data base and be supplemented and updated with data from the other sensors.

  7. Dr. Lytle Adams' incendiary "bat bomb" of World War II.

    PubMed

    Christen, Arden G; Christen, Joan A

    2004-11-01

    On December 7, 1941, a 60-year old dentist from Irwin, Pennsylvania, Dr. Lytle S. Adams, was driving home from a vacation at Carlsbad Caverns in New Mexico. Hours earlier, he had been gripped with amazement as he witnessed millions of bats exiting the caves of Carlsbad. Listening to his car radio on his return trip, he was shocked to hear that Japan had just attacked Pearl Harbor. Dr. Adams, outraged over this travesty, began to mentally construct a plan for U.S. retaliation. As his thoughts returned to the countless bats that had awed him, he formed a tentative plan: millions of these small, flying mammals could be connected to tiny, time-fused incendiary bombs, and then released to land on the flimsily constructed structures which dotted the cities of Japan. Within a few minutes, the bombs would explode and enflame the entire urban areas. He postulated that these immeasurable numbers of fires, spreading their devastation over such vast areas within Japanese cities would result in the enemy's speedy surrender. This article documents the futile efforts of Dr. Adams, his team and the U.S. government to develop and employ an effective, incendiary bat bomb. The recently developed atom bomb, a far more deadly weapon was used in its place.

  8. Dr Skateboard's Action Science: Teaching Physics in Context

    ERIC Educational Resources Information Center

    Robertson, William H.

    2009-01-01

    In order to create student interest and promote new connections to the understanding of fundamental physics concepts, there is a need for new approaches and methods that are both contemporary and relevant. Dr Skateboard's Action Science, a curriculum supplement comprising video instruction and classroom activities, is an example that focuses on…

  9. Dr.LiTHO: a development and research lithography simulator

    NASA Astrophysics Data System (ADS)

    Fühner, Tim; Schnattinger, Thomas; Ardelean, Gheorghe; Erdmann, Andreas

    2007-03-01

    This paper introduces Dr.LiTHO, a research and development oriented lithography simulation environment developed at Fraunhofer IISB to flexibly integrate our simulation models into one coherent platform. We propose a light-weight approach to a lithography simulation environment: The use of a scripting (batch) language as an integration platform. Out of the great variety of different scripting languages, Python proved superior in many ways: It exhibits a good-natured learning-curve, it is efficient, available on virtually any platform, and provides sophisticated integration mechanisms for existing programs. In this paper, we will describe the steps, required to provide Python bindings for existing programs and to finally generate an integrated simulation environment. In addition, we will give a short introduction into selected software design demands associated with the development of such a framework. We will especially focus on testing and (both technical and user-oriented) documentation issues. Dr.LiTHO Python files contain not only all simulation parameter settings but also the simulation flow, providing maximum flexibility. In addition to relatively simple batch jobs, repetitive tasks can be pooled in libraries. And as Python is a full-blown programming language, users can add virtually any functionality, which is especially useful in the scope of simulation studies or optimization tasks, that often require masses of evaluations. Furthermore, we will give a short overview of the numerous existing Python packages. Several examples demonstrate the feasibility and productiveness of integrating Python packages into custom Dr.LiTHO scripts.

  10. Summary of the geology and resources of uranium in the San Juan Basin and adjacent region, New Mexico, Arizona, Utah, and Colorado

    USGS Publications Warehouse

    Ridgley, Jennie L.; Green, M.W.; Pierson, C.T.; Finch, W.I.; Lupe, R.D.

    1978-01-01

    The San Juan Basin and adjacent region lie predominantly in the southeastern part of the uranium-rich Colorado Plateau of New Mexico, Arizona, Utah, and Colorado. Underlying the province are rocks of the Precambrian basement complex composed mainly of igneous and metamorphic rocks; a thickness of about 3,600 meters of generally horizontal Paleozoic, Mesozoic, and Cenozoic sedimentary rocks; and a variety of Upper Cretaceous and Cenozoic igneous rocks. Sedimentary rocks of the sequence are commonly eroded and well exposed near the present basin margins where Tertiary tectonic activity has uplifted, folded, and faulted the sequence into its present geologic configuration of basins, platforms, monoclines, and other related structural features. Sedimentary rocks of Jurassic age in the southern part of the San Juan Basin contain the largest uranium deposits in the United States, and offer the promise of additional uranium deposits. Elsewhere in the basin and the adjacent Colorado Plateau, reserves and resources of uranium are known primarily in Triassic, Jurassic, and Cretaceous strata. Only scattered occurrences of uranium are known in Paleozoic

  11. Blog Posts by the NCI Director Dr. Norman Sharpless

    Cancer.gov

    NCI Director Dr. Norman Sharpless writes posts regularly for NCI's Cancer Currents Blog that highlight his vision for NCI, meetings with and partnerships in the cancer community, and strategic and scientific initiatives to advance cancer research and care.

  12. Sequence of a new DR12 allele with two silent mutations that affect PCR-SSP typing.

    PubMed

    Zanone, R; Bettens, F; Tiercy, J-M

    2002-02-01

    A new HLA-DR12 allele has been identified in a European Caucasoid bone marrow donor. The DRB1*12012 allele differs from DRB1*12011 by two silent substitutions at codons 72 and 78, two polymorphic positions used for DNA subtyping of the DR12 serotype. The co-occurence of the two nucleotide changes is unique to the DR12 group and results in a new PCR-SSP typing pattern. The complete HLA type of the donor is A24, A68; B55, B61; Cw*01, Cw*0304; DRB1*12012, DRB1*1402; DRB3*0101, DRB3*0202; DQB1*0301. HLA-DRB1*12012 is a rare allele as it occurs in < 0.2% of DR12 donors.

  13. [Psychoanalysis in Buchenwald. Conversations between Bruno Bettelheim, Dr. Brief and Ernst Federn].

    PubMed

    Federn, E

    1988-01-01

    Ernst Federn met in the concentration camp Buchenwald Bruno Bettelheim and the Chechoslovakian psychoanalyst Dr. Brief. They discussed the application of psychoanalytic knowledge to the situation in the camp, particularly the defense mechanism of "identification with the aggressor". Of the three, Bettelheim was released after one year, Dr. Brief died in Ausschwitz and Ernst Federn was liberated by the U.S.A. Army. How he could use his psychoanalytic knowledge to survive but also to help fellow prisoners is demonstrated.

  14. The Case of Dr. Oz: Ethics, Evidence, and Does Professional Self-Regulation Work?

    PubMed

    Tilburt, Jon C; Allyse, Megan; Hafferty, Frederic W

    2017-02-01

    Dr. Mehmet Oz is widely known not just as a successful media personality donning the title "America's Doctor ® ," but, we suggest, also as a physician visibly out of step with his profession. A recent, unsuccessful attempt to censure Dr. Oz raises the issue of whether the medical profession can effectively self-regulate at all. It also raises concern that the medical profession's self-regulation might be selectively activated, perhaps only when the subject of professional censure has achieved a level of public visibility. We argue here that the medical profession must look at itself with a healthy dose of self-doubt about whether it has sufficient knowledge of or handle on the less visible Dr. "Ozes" quietly operating under the profession's presumptive endorsement. © 2017 American Medical Association. All Rights Reserved.

  15. Profile of prospective bioengineering students at National University of San Juan

    NASA Astrophysics Data System (ADS)

    Lopez, N.; Puzzella, A.; Zabala, A.; Demartini, H.; Alborch, A.; Cabrera, L.

    2007-11-01

    The low percentage of students (43 % of applicants) that passed the entrance exams for the bioengineering career at the National University of San Juan in 2007, plus the historical situation of desertion in first year (about 50%), motivated the application of a diagnostic test to prospective students of this career. The aim of this test was to obtain information about the competences acquired by students to solve problems in different contexts using basic mathematical tools, reading comprehension skills to understand texts, graphs and tables. Although this test was sat by the entire population of applicants of the current school year, only the results belonging to bioengineering students are the ones presented for the purpose of this work. However, students of other disciplines of the school of engineering also have similar problems. From the analysis of the answers to the different items, it can be observed that there are serious difficulties in the development of basic capacities to successfully take the courses of this career.

  16. Nitric oxide sensitizes tumor cells to TRAIL-induced apoptosis via inhibition of the DR5 transcription repressor Yin Yang 1.

    PubMed

    Huerta-Yepez, Sara; Vega, Mario; Escoto-Chavez, Saul E; Murdock, Benjamin; Sakai, Toshiyuki; Baritaki, Stavroula; Bonavida, Benjamin

    2009-02-01

    Treatment of TRAIL-resistant tumor cells with the nitric oxide donor DETANONOate sensitizes the tumor cells to TRAIL-induced apoptosis concomitantly with DR5 upregulation. The mechanism of sensitization was examined based on the hypothesis that DETANONOate inhibits a transcription repressor Yin Yang 1 (YY1) that negatively regulates DR5 transcription. Treatment of the prostate carcinoma cell lines with DETANONOate inhibited both NF-kappaB and YY1 DNA-binding activities concomitantly with upregulation of DR5 expression. The direct role of YY1 in the regulation of TRAIL resistance was demonstrated in cells treated with YY1 siRNA resulting in TRAIL-induced apoptosis. The role of YY1 in the transcriptional regulation of DR5 was examined in cells treated with a DR5 luciferase reporter system (pDR5) and two constructs, namely, the pDR5/-605 construct with a deletion of the putative YY1 DNA-binding region (-1224 to -605) and a construct pDR5-YY1 with a mutation of the YY1 DNA-binding site. A significant (3-fold) augmentation of luciferase activity over baseline transfection with pDR5 was observed in cells transfected with the modified constructs. ChIP analysis corroborated the YY1 binding to the DR5 promoter. In vivo, tissues from nude mice bearing the PC-3 xenograft and treated with DETANONOate showed inhibition of YY1 and upregulation of DR5. The present findings demonstrate that YY1 negatively regulates DR5 transcription and expression and these correlated with resistance to TRAIL-induced apoptosis. DETANONOate inhibits both NF-kappaB and YY1 and in combination with TRAIL reverses tumor cell resistance to TRAIL apoptosis.

  17. Oxygen and Metastasis: A Conversation with Dr. Nick Restifo

    Cancer.gov

    Dr. Nick Restifo, a senior investigator in NCI’s Center for Cancer Research, discusses his recently published study finding that Oxygen, a molecule necessary for life, paradoxically aids cancer metastasis to the lung by impairing cancer-killing immune cells.

  18. Focus on Fitness: Q&A with Dr. Greene

    ERIC Educational Resources Information Center

    Greene, Alan

    2005-01-01

    Dr. Greene answers the following question in this brief article focusing on fitness: Everyone knows that children need plenty of exercise to stay healthy--But what does "fitness" really involve for young children? Following this discussion, the topics presented include: snack of the month; nutrition fact; and activities, "Move to the Music" and…

  19. From surfaces to magnetic properties: special section dedicated to Juan Rojo

    NASA Astrophysics Data System (ADS)

    Mascaraque, A.; Rodríguez de la Fuente, O.; González-Barrio, Miguel A.

    2013-12-01

    Surface physics and magnetism, in particular the connection between surface defects, reduced dimensionality or size, crystal structure, electronic density of states and the mechanical and magnetic properties of solids, were always at the core of Juan Rojo's scientific interest and output. Both fields seem to meet at the nanoscale, a privileged playing field which is ideal for testing theoretical concepts, exploring new physics or probing a wealth of new, stunning and unheard-of applications. Upon reducing size or dimensionality, either in bulk systems or in thin films, surfaces and surface effects are telling. Thus, for instance, an ultra-thin coating can make nanoparticles of non-magnetic materials exhibit magnetic behaviour; or atomic steps can modify the local mechanical properties of a metallic single crystal. In this special section there are eight invited papers by disciples and close collaborators of Juan Rojo, that cover an ample spectrum of the above mentioned topics. The first paper, by Palacio et al, investigates the temperature and oxygen partial pressure conditions for FeO mono- and bi-layer growth on Ru(0001). The following paper, by Cortés-Gil et al, reports on the dramatic change in the electric resistivity of the manganite perovskite (La0.5Ca0.5)z MnO3 as a function of Ca content, an effect related to the removal of a charge-ordered state and a magnetic transition. Baeza et al study biomaterials for bone cancer treatment and skeletal reinforcing, as well as targeted magnetic nanoparticles used for intracell hyperthermia in cancer therapies. In the following paper, Marcano et al, assisted by a multi-technique approach, revisit the extraordinarily rich magnetic phase diagram of the Kondo system CeNi1- x Cux down to 100 mK temperatures. The magnetic field dependence of the martensitic transition temperature of the meta-magnetic shape memory alloy Ni50Mn34.5In15.5 in a crystalline and amorphous phase, in fields up to 13 T, is the subject of the paper

  20. [Comment on “IGBP: Crown jewel or prodigal son?” by Juan Roederer] IGBP and ICSU

    NASA Astrophysics Data System (ADS)

    Wooster, Warren S.

    Juan Roederer's article about IGBP (International Geosphere-Biosphere Program) and ICSU (International Council of Scientific Unions) in Eos, (“IGBP: Crown Jewel or Prodigal Son?” December 12, 1989, p. 1552) has interesting implications for the organization of international scientific cooperation within the framework of ICSU.In ICSU, power is divided between the International Scientific Union members and National Members (representing national academies and research councils). Even though the research sponsored by ICSU is done at national expense, and the operating expenses of ICSU come directly or indirectly from national sources, the Unions tend to hold the balance of power.