Sample records for narita japan nrt

  1. First report on invasion of yellow fever mosquito, Aedes aegypti, at Narita International Airport, Japan in August 2012.

    PubMed

    Sukehiro, Nayu; Kida, Nori; Umezawa, Masahiro; Murakami, Takayuki; Arai, Naoko; Jinnai, Tsunesada; Inagaki, Shunichi; Tsuchiya, Hidetoshi; Maruyama, Hiroshi; Tsuda, Yoshio

    2013-01-01

    The invasion of the yellow fever mosquito Aedes aegypti at Narita International Airport, Japan was detected for the first time. During the course of routine vector surveillance at Narita International Airport, 27 Ae. aegypti adults emerged from larvae and pupae collected from a single larvitrap placed near No. 88 spot at passenger terminal 2 on August 8, 2012. After the appearance of Ae. aegypti in the larvitrap, we defined a 400-m buffer zone and started an intensive vector survey using an additional 34 larvitraps and 15 CO2 traps. International aircraft and passenger terminal 2 were also inspected, and one Ae. aegypti male was collected from the cargo space of an international aircraft from Darwin via Manila on August 28, 2012. Larvicide treatment with 1.5% fenitrothion was conducted in 64 catch basins and one ditch in the 400-m buffer zone. Twenty-four large water tanks were also treated at least once with 0.5% pyriproxyfen, an insect growth regulator. No Ae. aegypti eggs or adults were found during the 1-month intensive vector survey after finding larvae and pupae in the larvitrap. We concluded that Ae. aegypti had failed to establish a population at Narita International Airport.

  2. Fever screening during the influenza (H1N1-2009) pandemic at Narita International Airport, Japan.

    PubMed

    Nishiura, Hiroshi; Kamiya, Kazuko

    2011-05-03

    Entry screening tends to start with a search for febrile international passengers, and infrared thermoscanners have been employed for fever screening in Japan. We aimed to retrospectively assess the feasibility of detecting influenza cases based on fever screening as a sole measure. Two datasets were collected at Narita International Airport during the 2009 pandemic. The first contained confirmed influenza cases (n = 16) whose diagnosis took place at the airport during the early stages of the pandemic, and the second contained a selected and suspected fraction of passengers (self-reported or detected by an infrared thermoscanner; n = 1,049) screened from September 2009 to January 2010. The sensitivity of fever (38.0 °C) for detecting H1N1-2009 was estimated, and the diagnostic performances of the infrared thermoscanners in detecting hyperthermia at cut-off levels of 37.5 °C, 38.0 °C and 38.5 °C were also estimated. The sensitivity of fever for detecting H1N1-2009 cases upon arrival was estimated to be 22.2% (95% confidence interval: 0, 55.6) among nine confirmed H1N1-2009 cases, and 55.6% of the H1N1-2009 cases were under antipyretic medications upon arrival. The sensitivity and specificity of the infrared thermoscanners in detecting hyperthermia ranged from 50.8-70.4% and 63.6-81.7%, respectively. The positive predictive value appeared to be as low as 37.3-68.0%. The sensitivity of entry screening is a product of the sensitivity of fever for detecting influenza cases and the sensitivity of the infrared thermoscanners in detecting fever. Given the additional presence of confounding factors and unrestricted medications among passengers, reliance on fever alone is unlikely to be feasible as an entry screening measure.

  3. Fever screening during the influenza (H1N1-2009) pandemic at Narita International Airport, Japan

    PubMed Central

    2011-01-01

    Background Entry screening tends to start with a search for febrile international passengers, and infrared thermoscanners have been employed for fever screening in Japan. We aimed to retrospectively assess the feasibility of detecting influenza cases based on fever screening as a sole measure. Methods Two datasets were collected at Narita International Airport during the 2009 pandemic. The first contained confirmed influenza cases (n = 16) whose diagnosis took place at the airport during the early stages of the pandemic, and the second contained a selected and suspected fraction of passengers (self-reported or detected by an infrared thermoscanner; n = 1,049) screened from September 2009 to January 2010. The sensitivity of fever (38.0°C) for detecting H1N1-2009 was estimated, and the diagnostic performances of the infrared thermoscanners in detecting hyperthermia at cut-off levels of 37.5°C, 38.0°C and 38.5°C were also estimated. Results The sensitivity of fever for detecting H1N1-2009 cases upon arrival was estimated to be 22.2% (95% confidence interval: 0, 55.6) among nine confirmed H1N1-2009 cases, and 55.6% of the H1N1-2009 cases were under antipyretic medications upon arrival. The sensitivity and specificity of the infrared thermoscanners in detecting hyperthermia ranged from 50.8-70.4% and 63.6-81.7%, respectively. The positive predictive value appeared to be as low as 37.3-68.0%. Conclusions The sensitivity of entry screening is a product of the sensitivity of fever for detecting influenza cases and the sensitivity of the infrared thermoscanners in detecting fever. Given the additional presence of confounding factors and unrestricted medications among passengers, reliance on fever alone is unlikely to be feasible as an entry screening measure. PMID:21539735

  4. High-affinity nitrate/nitrite transporters NrtA and NrtB of Aspergillus nidulans exhibit high specificity and different inhibitor sensitivity

    PubMed Central

    Akhtar, Naureen; Karabika, Eugenia; Kinghorn, James R.; Glass, Anthony D.M.; Unkles, Shiela E.

    2015-01-01

    The NrtA and NrtB nitrate transporters are paralogous members of the major facilitator superfamily in Aspergillus nidulans. The availability of loss-of-function mutations allowed individual investigation of the specificity and inhibitor sensitivity of both NrtA and NrtB. In this study, growth response tests were carried out at a growth-limiting concentration of nitrate (1 mM) as the sole nitrogen source, in the presence of a number of potential nitrate analogues at various concentrations, to evaluate their effect on nitrate transport. Both chlorate and chlorite inhibited fungal growth, with chlorite exerting the greater inhibition. The main transporter of nitrate, NrtA, proved to be more sensitive to chlorate than the minor transporter, NrtB. Similarly, the cation caesium was shown to exert differential effects, strongly inhibiting the activity of NrtB, but not NrtA. In contrast, no inhibition of nitrate uptake by NrtA or NrtB transporters was observed in either growth tests or uptake assays in the presence of bicarbonate, formate, malonate or oxalate (sulphite could not be tested in uptake assays owing to its reaction with nitrate), indicating significant specificity of nitrate transport. Kinetic analyses of nitrate uptake revealed that both chlorate and chlorite inhibited NrtA competitively, while these same inhibitors inhibited NrtB in a non-competitive fashion. The caesium ion appeared to inhibit NrtA in a non-competitive fashion, while NrtB was inhibited uncompetitively. The results provide further evidence of the distinctly different characteristics as well as the high specificity of nitrate uptake by these two transporters. PMID:25855763

  5. Norovirus Narita 104 Virus-Like Particles Expressed in Nicotiana benthamiana Induce Serum and Mucosal Immune Responses

    PubMed Central

    Mathew, Lolita George; Herbst-Kralovetz, Melissa M.; Mason, Hugh S.

    2014-01-01

    Narita 104 virus is a human pathogen belonging to the norovirus (family Caliciviridae) genogroup II. Noroviruses cause epidemic gastroenteritis worldwide. To explore the potential of developing a plant-based vaccine, a plant optimized gene encoding Narita 104 virus capsid protein (NaVCP) was expressed transiently in Nicotiana benthamiana using a tobacco mosaic virus expression system. NaVCP accumulated up to approximately 0.3 mg/g fresh weight of leaf at 4 days postinfection. Initiation of hypersensitive response-like symptoms followed by tissue necrosis necessitated a brief infection time and was a significant factor limiting expression. Transmission electron microscopy of plant-derived NaVCP confirmed the presence of fully assembled virus-like particles (VLPs). In this study, an optimized method to express and partially purify NaVCP is described. Further, partially purified NaVCP was used to immunize mice by intranasal delivery and generated significant mucosal and serum antibody responses. Thus, plant-derived Narita 104 VLPs have potential for use as a candidate subunit vaccine or as a component of a multivalent subunit vaccine, along with other genotype-specific plant-derived VLPs. PMID:24949472

  6. Two phloem nitrate transporters, NRT1.11 and NRT1.12, are important for redistributing xylem-borne nitrate to enhance plant growth.

    PubMed

    Hsu, Po-Kai; Tsay, Yi-Fang

    2013-10-01

    This study of the Arabidopsis (Arabidopsis thaliana) nitrate transporters NRT1.11 and NRT1.12 reveals how the interplay between xylem and phloem transport of nitrate ensures optimal nitrate distribution in leaves for plant growth. Functional analysis in Xenopus laevis oocytes showed that both NRT1.11 and NRT1.12 are low-affinity nitrate transporters. Quantitative reverse transcription-polymerase chain reaction and immunoblot analysis showed higher expression of these two genes in larger expanded leaves. Green fluorescent protein and β-glucuronidase reporter analyses indicated that NRT1.11 and NRT1.12 are plasma membrane transporters expressed in the companion cells of the major vein. In nrt1.11 nrt1.12 double mutants, more root-fed (15)NO3(-) was translocated to mature and larger expanded leaves but less to the youngest tissues, suggesting that NRT1.11 and NRT1.12 are required for transferring root-derived nitrate into phloem in the major veins of mature and larger expanded leaves for redistributing to the youngest tissues. Distinct from the wild type, nrt1.11 nrt1.12 double mutants show no increase of plant growth at high nitrate supply. These data suggested that NRT1.11 and NRT1.12 are involved in xylem-to-phloem transfer for redistributing nitrate into developing leaves, and such nitrate redistribution is a critical step for optimal plant growth enhanced by increasing external nitrate.

  7. Aspergillus oryzae nrtA affects kojic acid production.

    PubMed

    Sano, Motoaki

    2016-09-01

    We analyzed the role of the nitrate transporter-encoding gene (nrtA) of Aspergillus oryzae by gene disruption. Southern hybridization analysis indicated that homologous recombination occurred at the resident nrtA locus. Real-time PCR showed that the nrtA gene was strongly inducible by NaNO3. The nrtA disruptant did not exhibit normal growth when nitrate was available as the sole nitrogen source. These results indicate that NrtA is essential for nitrate uptake in A. oryzae. Kojic acid (KA) production was inhibited by the addition of a small amount of sodium nitrate. The nrtA-disrupted strain was deficient in the uptake of nitrate. As a result, KA production in this strain was not considerably affected by the presence of nitrate.

  8. NRT-1: Hazardous Materials Planning Guide

    EPA Pesticide Factsheets

    The NRT issued Hazardous Materials Emergency Planning Guide (NRT1) in 1987, as required by EPCRA, to provide planning guidance for state and local governments in the development of local emergency response plans.

  9. Informing future NRT satellite distribution capabilities: Lessons learned from NASA's Land Atmosphere NRT capability for EOS (LANCE)

    NASA Astrophysics Data System (ADS)

    Davies, D.; Murphy, K. J.; Michael, K.

    2013-12-01

    NASA's Land Atmosphere Near real-time Capability for EOS (Earth Observing System) (LANCE) provides data and imagery from Terra, Aqua and Aura satellites in less than 3 hours from satellite observation, to meet the needs of the near real-time (NRT) applications community. This article describes the architecture of the LANCE and outlines the modifications made to achieve the 3-hour latency requirement with a view to informing future NRT satellite distribution capabilities. It also describes how latency is determined. LANCE is a distributed system that builds on the existing EOS Data and Information System (EOSDIS) capabilities. To achieve the NRT latency requirement, many components of the EOS satellite operations, ground and science processing systems have been made more efficient without compromising the quality of science data processing. The EOS Data and Operations System (EDOS) processes the NRT stream with higher priority than the science data stream in order to minimize latency. In addition to expediting transfer times, the key difference between the NRT Level 0 products and those for standard science processing is the data used to determine the precise location and tilt of the satellite. Standard products use definitive geo-location (attitude and ephemeris) data provided daily, whereas NRT products use predicted geo-location provided by the instrument Global Positioning System (GPS) or approximation of navigational data (depending on platform). Level 0 data are processed in to higher-level products at designated Science Investigator-led Processing Systems (SIPS). The processes used by LANCE have been streamlined and adapted to work with datasets as soon as they are downlinked from satellites or transmitted from ground stations. Level 2 products that require ancillary data have modified production rules to relax the requirements for ancillary data so reducing processing times. Looking to the future, experience gained from LANCE can provide valuable lessons on

  10. Laboratory-confirmed dengue fever and chikungunya fever cases at the Narita Airport Quarantine Station in 2013.

    PubMed

    Furuichi, Mieko; Makie, Toshio; Honma, Yasuko; Isoda, Takayoshi; Miyake, Satoru

    2015-01-01

    Fourteen patients were laboratory-confirmed cases of imported infectious diseases at the Narita Airport Quarantine Station in 2013. Blood tests were performed on 283 subjects suspected of having imported infectious diseases. Of these, 11 were diagnosed as having dengue fever (dengue) and 3 as having chikungunya fever (chikungunya) using real-time RT-PCR. The possible countries from which dengue virus infections were contracted were Thailand, Laos, Sri Lanka, and some other countries in Southeast Asia and South Asia. The 3 chikungunya cases were also diagnosed in individuals that returned from Southeast Asia. Most of the patients with dengue had a fever of over 38℃. The other symptoms were generalized fatigue, dull headache, pain behind the eyes, arthralgia, and digestive symptoms. Four of the patients were unaware of any mosquito bites. The information obtained from the confirmed cases showed that it is important to consider both the destination to which individuals travelled and the clinical symptoms, regardless of whether the subjects were aware of mosquito bites. The detection rate of chikungunya at the Quarantine Station was higher than that of dengue in all reported cases in Japan.

  11. In low transpiring conditions, uncoupling the BnNrt2.1 and BnNrt1.1 NO3- transporters by glutamate treatment reveals the essential role of BnNRT2.1 for nitrate uptake and the nitrate-signaling cascade during growth

    PubMed Central

    Leblanc, Antonin; Segura, Raphaël; Deleu, Carole; Le Deunff, Erwan

    2013-01-01

    In plants, the nitrate transporters, NRT1.1 and NRT2.1, are mainly responsible for nitrate uptake. Intriguingly, both nitrate transporters are located in a complementary manner in different cells layers of the mature root suggesting that their coordination should occur during nitrate uptake and plant growth. This hypothesis was examined on 5-d-old rape seedlings grown on agar medium supplemented with 1 or 5mM nitrate. Seedlings were treated with increasing potassium glutamate concentrations in order to uncouple the two nitrate transporters by inhibiting BnNRT2.1 expression and activity specifically. In both nitrate treatments, increasing the glutamate concentrations from 0.5 to 10mM induced a reduction in 15NO3- uptake and an inhibition of N assimilation. The decrease in 15NO3- uptake was caused by downregulation of BnNRT2.1 expression but surprisingly it was not compensated by the upregulation of BnNRT1.1. This created an unprecedented physiological situation where the effects of the nitrate signal on shoot growth were solely modulated by nitrate absorption. In these conditions, the osmotic water flow for volumetric shoot growth was mainly dependent on active nitrate transport and nitrate signaling. This behavior was confirmed by the allometric relationships found between changes in the root length with 15N and water accumulation in the shoot. These findings demonstrate that the BnNRT2.1 transporter is essential for nitrate uptake and growth, and renew the question of the respective roles of the NRT2.1 and NRT1.1 transporters in nitrate uptake and sensing at the whole plant level. PMID:23299418

  12. Arabidopsis Nitrate Transporter NRT1.9 Is Important in Phloem Nitrate Transport[W][OA

    PubMed Central

    Wang, Ya-Yun; Tsay, Yi-Fang

    2011-01-01

    This study of the Arabidopsis thaliana nitrate transporter NRT1.9 reveals an important function for a NRT1 family member in phloem nitrate transport. Functional analysis in Xenopus laevis oocytes showed that NRT1.9 is a low-affinity nitrate transporter. Green fluorescent protein and β-glucuronidase reporter analyses indicated that NRT1.9 is a plasma membrane transporter expressed in the companion cells of root phloem. In nrt1.9 mutants, nitrate content in root phloem exudates was decreased, and downward nitrate transport was reduced, suggesting that NRT1.9 may facilitate loading of nitrate into the root phloem and enhance downward nitrate transport in roots. Under high nitrate conditions, the nrt1.9 mutant showed enhanced root-to-shoot nitrate transport and plant growth. We conclude that phloem nitrate transport is facilitated by expression of NRT1.9 in root companion cells. In addition, enhanced root-to-shoot xylem transport of nitrate in nrt1.9 mutants points to a negative correlation between xylem and phloem nitrate transport. PMID:21571952

  13. Mutation of the Arabidopsis NRT1.5 nitrate transporter causes defective root-to-shoot nitrate transport.

    PubMed

    Lin, Shan-Hua; Kuo, Hui-Fen; Canivenc, Geneviève; Lin, Choun-Sea; Lepetit, Marc; Hsu, Po-Kai; Tillard, Pascal; Lin, Huey-Ling; Wang, Ya-Yun; Tsai, Chyn-Bey; Gojon, Alain; Tsay, Yi-Fang

    2008-09-01

    Little is known about the molecular and regulatory mechanisms of long-distance nitrate transport in higher plants. NRT1.5 is one of the 53 Arabidopsis thaliana nitrate transporter NRT1 (Peptide Transporter PTR) genes, of which two members, NRT1.1 (CHL1 for Chlorate resistant 1) and NRT1.2, have been shown to be involved in nitrate uptake. Functional analysis of cRNA-injected Xenopus laevis oocytes showed that NRT1.5 is a low-affinity, pH-dependent bidirectional nitrate transporter. Subcellular localization in plant protoplasts and in planta promoter-beta-glucuronidase analysis, as well as in situ hybridization, showed that NRT1.5 is located in the plasma membrane and is expressed in root pericycle cells close to the xylem. Knockdown or knockout mutations of NRT1.5 reduced the amount of nitrate transported from the root to the shoot, suggesting that NRT1.5 participates in root xylem loading of nitrate. However, root-to-shoot nitrate transport was not completely eliminated in the NRT1.5 knockout mutant, and reduction of NRT1.5 in the nrt1.1 background did not affect root-to-shoot nitrate transport. These data suggest that, in addition to that involving NRT1.5, another mechanism is responsible for xylem loading of nitrate. Further analyses of the nrt1.5 mutants revealed a regulatory loop between nitrate and potassium at the xylem transport step.

  14. Impact of a Temporary NRT Enhancement in a State Quitline and Web-Based Program.

    PubMed

    Cole, Sam; Suter, Casey; Nash, Chelsea; Pollard, Joseph

    2018-06-01

    To examine the impact of a nicotine replacement therapy (NRT) enhancement on quit outcomes. Observational study using an intent to treat as treated analysis. Not available. A total of 4022 Idaho tobacco users aged ≥18 years who received services from the Idaho Tobacco Quitline or Idaho's web-based program. One-call phone or web-based participants were sent a single 4- or 8-week NRT shipment. Multiple-call participants were sent NRT in a single 4-week shipment or two 4-week shipments (second shipment sent only to those completing a second coaching call). North American Quitline Consortium recommended Minimal Data Set items collected at registration and follow-up. Thirty-day point prevalence quit rates were assessed at 7-month follow-up. Multiple logistic regression models were used to examine the effects of program type and amount of NRT sent to participants while controlling for demographic and tobacco use characteristics. Abstinence rates were significantly higher among 8-week versus 4-week NRT recipients (42.5% vs 33.3%). The effect was only significant between multiple-call program participants who received both 4-week NRT shipments versus only the first of 2 possible 4-week shipments (51.1% vs 31.1%). Costs per quit were lowest among web-based participants who received 4 weeks of NRT (US$183 per quit) and highest among multiple-call participants who received only 1 of 2 possible NRT shipments (US$557 per quit). To better balance cost with clinical effectiveness, funders of state-based tobacco cessation services may want to consider (1) allowing tobacco users to choose between phone- and web-based programs while (2) limiting longer NRT benefits only to multiple-call program participants.

  15. Proanthocyanidin oxidation of Arabidopsis seeds is altered in mutant of the high-affinity nitrate transporter NRT2.7

    PubMed Central

    David, Laure C.; Dechorgnat, Julie; Ferrario-Méry, Sylvie

    2014-01-01

    NRT2.7 is a seed-specific high-affinity nitrate transporter controlling nitrate content in Arabidopsis mature seeds. The objective of this work was to analyse further the consequences of the nrt2.7 mutation for the seed metabolism. This work describes a new phenotype for the nrt2.7-2 mutant allele in the Wassilewskija accession, which exhibited a distinctive pale-brown seed coat that is usually associated with a defect in flavonoid oxidation. Indeed, this phenotype resembled those of tt10 mutant seeds defective in the laccase-like enzyme TT10/LAC15, which is involved in the oxidative polymerization of flavonoids such as the proantocyanidins (PAs) (i.e. epicatechin monomers and PA oligomers) and flavonol glycosides. nrt2.7-2 and tt10-2 mutant seeds displayed the same higher accumulation of PAs, but were partially distinct, since flavonol glycoside accumulation was not affected in the nrt2.7-2 seeds. Moreover, measurement of in situ laccase activity excluded a possibility of the nrt2.7-2 mutation affecting the TT10 enzymic activity at the early stage of seed development. Functional complementation of the nrt2.7-2 mutant by overexpression of a full-length NRT2.7 cDNA clearly demonstrated the link between the nrt2.7 mutation and the PA phenotype. However, the PA-related phenotype of nrt2.7-2 seeds was not strictly correlated to the nitrate content of seeds. No correlation was observed when nitrate was lowered in seeds due to limited nitrate nutrition of plants or to lower nitrate storage capacity in leaves of clca mutants deficient in the vacuolar anionic channel CLCa. All together, the results highlight a hitherto-unknown function of NRT2.7 in PA accumulation/oxidation. PMID:24532452

  16. National Response Team (NRT) Member Roles and Responsibilities

    EPA Pesticide Factsheets

    EPA personnel chair the NRT and cochair all Regional Response Teams (RRTs). They provide On-Scene Coordinators (OSCs), scientific support coordinators for inland spills, and Remedial Project Managers for hazardous waste remedial actions under Superfund.

  17. Prevalence of NRT use and associated nicotine intake in smokers, recent ex-smokers and longer-term ex-smokers.

    PubMed

    Shahab, Lion; Beard, Emma; Brown, Jamie; West, Robert

    2014-01-01

    Nicotine replacement therapy (NRT) is used by smokers wanting to reduce their smoking and to quit. However, there are very little data on nicotine intake associated with NRT use in representative population samples. This study aimed to provide estimates for NRT use and associated nicotine exposure among smokers, recent and longer-term ex-smokers in England, a country with a permissive regulatory regime for nicotine substitution. In the Smoking Toolkit Study, a monthly series of representative household surveys of adults aged 16+ in England, current and recent ex-smokers who agreed to be re-contacted were followed up 6 months later and standard socio-demographic and smoking characteristics assessed (N = 5,467, response rate 25.1%). A random sub-sample (N = 1,614; 29.5%) also provided saliva, analysed for cotinine. The sample followed up was broadly representative of the original sample. At follow-up, 11.8% (95%CI 10.9-12.8, N = 565) of current smokers, 34.8% (95%CI 28.9-41.3, N = 77) of recent (≤ 3 months) ex-smokers, and 7.8% (95%CI 5.6-10.6, N = 36) of longer-term (> 3 months) ex-smokers reported using NRT. Smokers who used NRT had similar saliva cotinine concentrations to smokers who did not use NRT (mean ± sd  = 356.0 ± 198.6 ng/ml vs. 313.1 ± 178.4 ng/ml). Recent ex-smokers who used NRT had levels that were somewhat lower, but not significantly so, than current smokers (216.7 ± 179.3 ng/ml). Longer-term ex-smokers using NRT had still lower levels (157.3 ± 227.1 ng/ml), which differed significantly from smokers using NRT (p = 0.024). Concurrent use of nicotine replacement therapy while smoking is relatively uncommon and is not associated with higher levels of nicotine intake. Among ex-smokers, NRT use is common in the short but not longer-term and among longer-term users is associated with lower nicotine intake than in smokers.

  18. Nitrate Controls Root Development through Posttranscriptional Regulation of the NRT1.1/NPF6.3 Transporter/Sensor1

    PubMed Central

    Perrine-Walker, Francine; Rochette, Juliette; Martinière, Alexandre; Bach, Lien; Gojon, Alain

    2016-01-01

    Plants are able to modulate root growth and development to optimize their nitrogen nutrition. In Arabidopsis (Arabidopsis thaliana), the adaptive root response to nitrate (NO3−) depends on the NRT1.1/NPF6.3 transporter/sensor. NRT1.1 represses emergence of lateral root primordia (LRPs) at low concentration or absence of NO3− through its auxin transport activity that lowers auxin accumulation in LR. However, these functional data strongly contrast with the known transcriptional regulation of NRT1.1, which is markedly repressed in LRPs in the absence of NO3−. To explain this discrepancy, we investigated in detail the spatiotemporal expression pattern of the NRT1.1 protein during LRP development and combined local transcript analysis with the use of transgenic lines expressing tagged NRT1.1 proteins. Our results show that although NO3− stimulates NRT1.1 transcription and probably mRNA stability both in primary root tissues and in LRPs, it acts differentially on protein accumulation, depending on the tissues considered with stimulation in cortex and epidermis of the primary root and a strong repression in LRPs and to a lower extent at the primary root tip. This demonstrates that NRT1.1 is strongly regulated at the posttranscriptional level by tissue-specific mechanisms. These mechanisms are crucial for controlling the large palette of adaptive responses to NO3− mediated by NRT1.1 as they ensure that the protein is present in the proper tissue under the specific conditions where it plays a signaling role in this particular tissue. PMID:27543115

  19. Impact and Effectiveness of a Stand-Alone NRT Starter Kit in a Statewide Tobacco Cessation Program.

    PubMed

    Kerr, Amy N; Schillo, Barbara A; Keller, Paula A; Lachter, Randi B; Lien, Rebecca K; Zook, Heather G

    2018-01-01

    To examine 2-week nicotine replacement therapy (NRT) starter kit quit outcomes and predictors and the impact of adding this new service on treatment reach. Observational study of a 1-year cohort of QUITPLAN Services enrollees using registration and utilization data and follow-up outcome survey data of a subset of enrollees who received NRT starter kits. ClearWay Minnesota's QUITPLAN Services provides a quit line that is available to uninsured and underinsured Minnesotans and NRT starter kits (a free 2-week supply of patches, gum, or lozenges) that are available to all Minnesota tobacco users. A total of 15 536 adult QUITPLAN Services enrollees and 818 seven-month follow-up survey NRT starter kit respondents. Treatment reach for all services and tobacco quit outcomes and predictors for starter kit recipients. Descriptive analyses, χ 2 analyses, and logistic regression. Treatment reach increased 3-fold after adding the 2-week NRT starter kit service option to QUITPLAN Services compared to the prior year (1.86% vs 0.59%). Among all participants enrolling in QUITPLAN services during a 1-year period, 83.8% (13 026/15 536) registered for a starter kit. Among starter kit respondents, 25.6% reported being quit for 30 days at the 7-month follow-up. After controlling for other factors, using all NRT and selecting more cessation services predicted quitting. An NRT starter kit brought more tobacco users to QUITPLAN services, demonstrating interest in cessation services separate from phone counseling. The starter kit produced high quit rates, comparable to the quit line in the same time period. Cessation service providers may want to consider introducing starter kits to reach more tobacco users and ultimately improve population health.

  20. Dual regulation of root hydraulic conductivity and plasma membrane aquaporins by plant nitrate accumulation and high-affinity nitrate transporter NRT2.1.

    PubMed

    Li, Guowei; Tillard, Pascal; Gojon, Alain; Maurel, Christophe

    2016-04-01

    The water status and mineral nutrition of plants critically determine their growth and development. Nitrate (NO3(-)), the primary nitrogen source of higher plants, is known to impact the water transport capacity of roots (root hydraulic conductivity, Lpr). To explore the effects and mode of action of NO3(-) on Lpr, we used an extended set of NO3(-) transport (nrt1.1, nrt1.2, nrt1.5 and nrt2.1), signaling (nrt1.1 and nrt2.1) and metabolism (nia) mutants in Arabidopsis, grown under various NO3(-) conditions. First, a strong positive relationship between Lpr and NO3(-) accumulation, in shoots rather than in roots, was revealed. Secondly, a specific 30% reduction of Lpr in nrt2.1 plants unraveled a major role for the high-affinity NO3(-) transporter NRT2.1 in increasing Lpr These results indicate that NO3(-)signaling rather than nitrogen assimilation products governs Lpr in Arabidopsis. Quantitative real-time reverse transcription-PCR and enzyme-linked immunosorbent assays (ELISAs) were used to investigate the effects of NO3(-) availability on plasma membrane aquaporin (plasma membrane intrinsic protein; PIP) expression. Whereas PIP regulation mostly occurs at the post-translational level in wild-type plants, a regulation of PIPs at both the transcriptional and translational levels was uncovered in nrt2.1 plants. In conclusion, this work reveals that control of Arabidopsis Lpr and PIP functions by NO3(-) involves novel shoot to root signaling and NRT2.1-dependent functions. © The Author 2016. Published by Oxford University Press on behalf of Japanese Society of Plant Physiologists. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  1. NASA's Land, Atmosphere Near real-time Capability for EOS (LANCE): Changing patterns in the use of NRT satellite imagery

    NASA Astrophysics Data System (ADS)

    Davies, D.; Michael, K.; Schmaltz, J. E.; Harrison, S.; Ding, F.; Durbin, P. B.; Boller, R. A.; Cechini, M. F.; Rinsland, P. L.; Ye, G.; Mauoka, E.

    2015-12-01

    NASA's Land, Atmosphere Near real-time Capability for EOS (Earth Observing System) (LANCE) provides data and imagery approximately 3 hours from satellite observation, to monitor natural events globally and to meet the needs of the near real-time (NRT) applications community. This article describes LANCE, and how the use of NRT data and imagery has evolved. Since 2010 there has been a four-fold increase in both the volume of data and the number of files downloaded. Over the last year there has been a marked shift in the way in which users are accessing NRT imagery; users are gravitating towards Worldview and the Global Imagery Browse Services (GIBS) and away from MODIS Rapid Response, in part due to the increased exposure through social media. In turn this is leading to a broader range of users viewing NASA NRT imagery. This article also describes new, and planned, product enhancements to LANCE. Over the last year, LANCE has expanded to support NRT products from the Advanced Microwave Scanning Radiometer 2 (AMSR2), and the Multi-angle Imaging SpectroRadiometer (MISR). LANCE elements are also planning to ingest and process NRT data from the Visible Infrared Imager Radiometer Suite (VIIRS), and the advanced Ozone Mapping and Profiler Suite (OMPS) instruments onboard the Suomi National Polar-orbiting Partnership (S-NPP) satellite in the near future.

  2. NRT1.5/NPF7.3 Functions as a Proton-Coupled H+/K+ Antiporter for K+ Loading into the Xylem in Arabidopsis.

    PubMed

    Li, Hong; Yu, Miao; Du, Xin-Qiao; Wang, Zhi-Fang; Wu, Wei-Hua; Quintero, Francisco J; Jin, Xue-Hua; Li, Hao-Dong; Wang, Yi

    2017-08-01

    Potassium and nitrogen are essential macronutrients for plant growth and have a positive impact on crop yield. Previous studies have indicated that the absorption and translocation of K + and NO 3 - are correlated with each other in plants; however, the molecular mechanism that coordinates K + and NO 3 - transport remains unknown. In this study, using a forward genetic approach, we isolated a low-K + -sensitive Arabidopsis thaliana mutant, lks2 , that showed a leaf chlorosis phenotype under low-K + conditions. LKS2 encodes the transporter NRT1.5/NPF7.3, a member of the NRT1/PTR (Nitrate Transporter 1/Peptide Transporter) family. The lks2 / nrt1.5 mutants exhibit a remarkable defect in both K + and NO 3 - translocation from root to shoot, especially under low-K + conditions. This study demonstrates that LKS2 (NRT1.5) functions as a proton-coupled H + /K + antiporter. Proton gradient can promote NRT1.5-mediated K + release out of root parenchyma cells and facilitate K + loading into the xylem. This study reveals that NRT1.5 plays a crucial role in K + translocation from root to shoot and is also involved in the coordination of K + /NO 3 - distribution in plants. © 2017 American Society of Plant Biologists. All rights reserved.

  3. Metabolic Flux Analysis of the Synechocystis sp. PCC 6803 ΔnrtABCD Mutant Reveals a Mechanism for Metabolic Adaptation to Nitrogen-Limited Conditions.

    PubMed

    Nakajima, Tsubasa; Yoshikawa, Katsunori; Toya, Yoshihiro; Matsuda, Fumio; Shimizu, Hiroshi

    2017-03-01

    Metabolic flux redirection during nitrogen-limited growth was investigated in the Synechocystis sp. PCC 6803 glucose-tolerant (GT) strain under photoautotrophic conditions by isotopically non-stationary metabolic flux analysis (INST-MFA). A ΔnrtABCD mutant of Synechocystis sp. PCC 6803 was constructed to reproduce phenotypes arising during nitrogen starvation. The ΔnrtABCD mutant and the wild-type GT strain were cultured under photoautotrophic conditions by a photobioreactor. Intracellular metabolites were labeled over a time course using NaH13CO3 as a carbon source. Based on these data, the metabolic flux distributions in the wild-type and ΔnrtABCD cells were estimated by INST-MFA. The wild-type GT and ΔnrtABCD strains displayed similar distribution patterns, although the absolute levels of metabolic flux were lower in ΔnrtABCD. Furthermore, the relative flux levels for glycogen metabolism, anaplerotic reactions and the oxidative pentose phosphate pathway were increased in ΔnrtABCD. This was probably due to the increased expression of enzyme genes that respond to nitrogen depletion. Additionally, we found that the ratio of ATP/NADPH demand increased slightly in the ΔnrtABCD mutant. These results indicated that futile ATP consumption increases under nitrogen-limited conditions because the Calvin-Benson cycle and the oxidative pentose phosphate pathway form a metabolic futile cycle that consumes ATP without CO2 fixation and NADPH regeneration. © The Author 2017. Published by Oxford University Press on behalf of Japanese Society of Plant Physiologists. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  4. Knock-Down of CsNRT2.1, a Cucumber Nitrate Transporter, Reduces Nitrate Uptake, Root length, and Lateral Root Number at Low External Nitrate Concentration

    PubMed Central

    Li, Yang; Li, Juanqi; Yan, Yan; Liu, Wenqian; Zhang, Wenna; Gao, Lihong; Tian, Yongqiang

    2018-01-01

    Nitrogen (N) is a macronutrient that plays a crucial role in plant growth and development. Nitrate (NO3-) is the most abundant N source in aerobic soils. Plants have evolved two adaptive mechanisms such as up-regulation of the high-affinity transport system (HATS) and alteration of the root system architecture (RSA), allowing them to cope with the temporal and spatial variation of NO3-. However, little information is available regarding the nitrate transporter in cucumber, one of the most important fruit vegetables in the world. In this study we isolated a nitrate transporter named CsNRT2.1 from cucumber. Analysis of the expression profile of the CsNRT2.1 showed that CsNRT2.1 is a high affinity nitrate transporter which mainly located in mature roots. Subcellular localization analysis revealed that CsNRT2.1 is a plasma membrane transporter. In N-starved CsNRT2.1 knock-down plants, both of the constitutive HATS (cHATS) and inducible HATS (iHATS) were impaired under low external NO3- concentration. Furthermore, the CsNRT2.1 knock-down plants showed reduced root length and lateral root numbers. Together, our results demonstrated that CsNRT2.1 played a dual role in regulating the HATS and RSA to acquire NO3- effectively under N limitation. PMID:29911677

  5. Cost-Effectiveness Analysis of Smoking Cessation Interventions in Japan Using a Discrete-Event Simulation.

    PubMed

    Igarashi, Ataru; Goto, Rei; Suwa, Kiyomi; Yoshikawa, Reiko; Ward, Alexandra J; Moller, Jörgen

    2016-02-01

    Smoking cessation medications have been shown to yield higher success rates and sustained abstinence than unassisted quit attempts. In Japan, the treatments available include nicotine replacement therapy (NRT) and varenicline; however, unassisted attempts to quit smoking remain common. The objective of this study was to compare the health and economic consequences in Japan of using pharmacotherapy to support smoking cessation with unassisted attempts and the current mix of strategies used. A discrete-event simulation that models lifetime quitting behaviour and includes multiple quit attempts (MQAs) and relapses was adapted for these analyses. The risk of developing smoking-related diseases is estimated based on the duration of abstinence. Data collected from a survey conducted in Japan were used to determine the interventions selected by smokers initiating a quit attempt and the time between MQAs. Direct and indirect costs are assessed (expressed in 2014 Japanese Yen). Using pharmacotherapy (NRT or varenicline) to support quit attempts proved to be dominant when compared with unassisted attempts or the current mix of strategies (most are unassisted). The results of stratified analyses by age imply that smoking cessation improves health outcomes across all generations. Indirect costs due to premature death leading to lost wages are an important component of the total costs, exceeding the direct medical cost estimates. Increased utilisation of smoking cessation pharmacotherapy to support quit attempts is predicted to lead to an increase in the number of smokers achieving abstinence, and provide improvements in health outcomes over a lifetime with no additional costs.

  6. Regulation of the High-Affinity NO3− Uptake System by NRT1.1-Mediated NO3− Demand Signaling in Arabidopsis[W

    PubMed Central

    Krouk, Gabriel; Tillard, Pascal; Gojon, Alain

    2006-01-01

    The NRT2.1 gene of Arabidopsis thaliana encodes a major component of the root high-affinity \\documentclass[10pt]{article} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{pmc} \\pagestyle{empty} \\oddsidemargin -1.0in \\begin{document} \\begin{equation*}{\\mathrm{NO}}_{3}^{-}\\end{equation*}\\end{document} transport system (HATS) that plays a crucial role in \\documentclass[10pt]{article} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{pmc} \\pagestyle{empty} \\oddsidemargin -1.0in \\begin{document} \\begin{equation*}{\\mathrm{NO}}_{3}^{-}\\end{equation*}\\end{document} uptake by the plant. Although NRT2.1 was known to be induced by \\documentclass[10pt]{article} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{pmc} \\pagestyle{empty} \\oddsidemargin -1.0in \\begin{document} \\begin{equation*}{\\mathrm{NO}}_{3}^{-}\\end{equation*}\\end{document} and feedback repressed by reduced nitrogen (N) metabolites, NRT2.1 is surprisingly up-regulated when \\documentclass[10pt]{article} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{pmc} \\pagestyle{empty} \\oddsidemargin -1.0in \\begin{document} \\begin{equation*}{\\mathrm{NO}}_{3}^{-}\\end{equation*}\\end{document} concentration decreases to a low level (<0.5 mm) in media containing a high concentration of \\documentclass[10pt]{article} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{pmc} \\pagestyle{empty} \\oddsidemargin -1.0in \\begin{document} \\begin{equation*}{\\mathrm{NH}}_{4}^{+}\\end{equation*}\\end{document} or Gln (≥1 mm). The NRT3

  7. What happens when GPs proactively prescribe NRT patches in a disadvantaged community.

    PubMed

    Copeland, L; Robertson, R; Elton, R

    2005-05-01

    The high prevalence of smoking in disadvantaged communities gives serious cause for concern in terms of adverse effects on health and social outcomes. In Scotland, smoking -related lung cancer rates are particularly high and compare less favourably with the rest of the U.K. and Europe. GPs are increasingly being recognised as having an important role in smoking cessation and are allowed to prescribe NRT to those on a low income. This study aimed to follow up a group patientsfrom a disadvantaged area who had been prescribed nicotine patches by their GP. An initial self-complete questionnaire gathered details on age, sex, motivation, marital status, employment history, contact with other smokers, concern about weight gain, and nicotine dependence. (Nicotine dependence was assessed by using the Fagerstrom Test). Follow up was carried out at three months after commencing NRT prescription. Data was also gathered from patient case notes as to whether the participant had a smoking-related diagnosis, periods of depression, drug and/or alcohol problems. Outcome was measured in terms of "smoke the same", "smoke less" and "stopped". The statistical methods used for testing each factor against smoking were Spearman rank correlation, chi-squared test for trend and Kruskal-Wallis test. Basic descriptive statistics were used to report general outcomes of the study. The study enrolled 120 patients but 19 were lost to follow up. Out of 101 who used their prescription, 35 were smoking the same, 46 were smoking less and 20 had stopped. The variables most strongly affecting outcome were age, with older smokers having more success (p < 0.001), and those who had a diagnosis of depression having a worse outcome in terms of smoking cessation (p < 0.05). This study's findings indicate that encouraging GPs to take a proactive approach in prescribing NRT is effective, even in an area of socio-economic deprivation, and particularly with older smokers.

  8. Saccharomyces cerevisiae YOR071C encodes the high affinity nicotinamide riboside transporter Nrt1.

    PubMed

    Belenky, Peter A; Moga, Tiberiu G; Brenner, Charles

    2008-03-28

    NAD(+) is an essential coenzyme for hydride transfer enzymes and a substrate of sirtuins and other NAD(+)-consuming enzymes. Nicotinamide riboside is a recently discovered eukaryotic NAD(+) precursor converted to NAD(+) via the nicotinamide riboside kinase pathway and by nucleosidase activity and nicotinamide salvage. Nicotinamide riboside supplementation of yeast extends replicative life span on high glucose medium. The molecular basis for nicotinamide riboside uptake was unknown in any eukaryote. Here, we show that deletion of a single gene, YOR071C, abrogates nicotinamide riboside uptake without altering nicotinic acid or nicotinamide import. The gene, which is negatively regulated by Sum1, Hst1, and Rfm1, fully restores nicotinamide riboside import and utilization when resupplied to mutant yeast cells. The encoded polypeptide, Nrt1, is a predicted deca-spanning membrane protein related to the thiamine transporter, which functions as a pH-dependent facilitator with a K(m) for nicotinamide riboside of 22 microm. Nrt1-related molecules are conserved in particular fungi, suggesting a similar basis for nicotinamide riboside uptake.

  9. NRT Atmospheric Water Vapour Retrieval on the Area of Poland at IGG WUELS AC

    NASA Astrophysics Data System (ADS)

    Kaplon, Jan; Bosy, Jaroslaw; Sierny, Jan; Hadas, Tomasz; Rohm, Witold; Wilgan, Karina; Ryczywolski, Marcin; Oruba, Artur; Kroszczynski, Krzysztof

    2013-04-01

    Global Navigation Satellite Systems (GNSS) are designed for positioning, navigation and amongst other possible applications it can also be used to derive information about the state of the atmosphere. Continuous observations from GNSS receivers provide an excellent tool for studying the neutral atmosphere, currently in near real-time. The Near Real-Time (NRT) neutral atmosphere and water vapour distribution models are currently obtained with high resolution from Ground Base Augmentation Systems (GBAS), where reference stations are equipped with GNSS and meteorological sensors. The Poland territory is covered by dense network of GNSS stations in the frame of GBAS system called ASG-EUPOS (www.asgeupos.pl). This system was established in year 2008 by the Head Office of Geodesy and Cartography in the frame of the EUPOS project (www.eupos.org) for providing positioning services. The GNSS data are available from 130 reference stations located in Poland and neighbour countries. The ground meteorological observations in the area of Poland and neighbour countries are available from ASG-EUPOS stations included in EUREF Permanent Network (EPN) stations, airports meteorological stations (METAR messages stations), and stations managed by national Institute of Meteorology and Water Management (SYNOP messages stations). Institute of Geodesy and Geoinformatics (IGG) of Wroclaw University of Environmental and Life Sciences had created permanent NRT service of ZTD (Zenith Total Delay) estimation for the area of Poland from GPS observations called IGGHZG. The first part of the paper presents the methodology of NRT GNSS data processing for ASG-EUPOS stations for ZTD estimation and its comparison to the results coming from EPN ACs and Military University of Technology in Warsaw AC (MUT AC). Second part covers the procedure of IWV (atmospheric Integrated Water Vapour content) estimation at IGG from IGGHZG product and ZHD (Zenith Hydrostatic Delay) derived from Saastamoinen formula (1972

  10. Expression of the Nitrate Transporter Gene OsNRT1.1A/OsNPF6.3 Confers High Yield and Early Maturation in Rice[OPEN

    PubMed Central

    Wang, Wei; Hu, Bin; Liu, Yongqiang; Che, Ronghui; Hu, Yingchun; Zhang, Zhihua; Wang, Hongru; Li, Hua; Jiang, Zhimin; Zhang, Zhengli; Gao, Xiaokai; Qiu, Yahong; Meng, Xiangbing; Liu, Yongxin; Bai, Yang; Liang, Yan; Wang, Yiqin; Zhang, Lianhe; Li, Legong; Sodmergen; Jing, Haichun

    2018-01-01

    Nitrogen (N) is a major driving force for crop yield improvement, but application of high levels of N delays flowering, prolonging maturation and thus increasing the risk of yield losses. Therefore, traits that enable utilization of high levels of N without delaying maturation will be highly desirable for crop breeding. Here, we show that OsNRT1.1A (OsNPF6.3), a member of the rice (Oryza sativa) nitrate transporter 1/peptide transporter family, is involved in regulating N utilization and flowering, providing a target to produce high yield and early maturation simultaneously. OsNRT.1A has functionally diverged from previously reported NRT1.1 genes in plants and functions in upregulating the expression of N utilization-related genes not only for nitrate but also for ammonium, as well as flowering-related genes. Relative to the wild type, osnrt1.1a mutants exhibited reduced N utilization and late flowering. By contrast, overexpression of OsNRT1.1A in rice greatly improved N utilization and grain yield, and maturation time was also significantly shortened. These effects were further confirmed in different rice backgrounds and also in Arabidopsis thaliana. Our study paves a path for the use of a single gene to dramatically increase yield and shorten maturation time for crops, outcomes that promise to substantially increase world food security. PMID:29475937

  11. Expression of the Nitrate Transporter Gene OsNRT1.1A/OsNPF6.3 Confers High Yield and Early Maturation in Rice.

    PubMed

    Wang, Wei; Hu, Bin; Yuan, Dingyang; Liu, Yongqiang; Che, Ronghui; Hu, Yingchun; Ou, Shujun; Liu, Yongxin; Zhang, Zhihua; Wang, Hongru; Li, Hua; Jiang, Zhimin; Zhang, Zhengli; Gao, Xiaokai; Qiu, Yahong; Meng, Xiangbing; Liu, Yongxin; Bai, Yang; Liang, Yan; Wang, Yiqin; Zhang, Lianhe; Li, Legong; Sodmergen; Jing, Haichun; Li, Jiayang; Chu, Chengcai

    2018-03-01

    Nitrogen (N) is a major driving force for crop yield improvement, but application of high levels of N delays flowering, prolonging maturation and thus increasing the risk of yield losses. Therefore, traits that enable utilization of high levels of N without delaying maturation will be highly desirable for crop breeding. Here, we show that OsNRT1.1A (OsNPF6.3), a member of the rice ( Oryza sativa ) nitrate transporter 1/peptide transporter family, is involved in regulating N utilization and flowering, providing a target to produce high yield and early maturation simultaneously. OsNRT.1A has functionally diverged from previously reported NRT1.1 genes in plants and functions in upregulating the expression of N utilization-related genes not only for nitrate but also for ammonium, as well as flowering-related genes. Relative to the wild type, osnrt1.1a mutants exhibited reduced N utilization and late flowering. By contrast, overexpression of OsNRT1.1A in rice greatly improved N utilization and grain yield, and maturation time was also significantly shortened. These effects were further confirmed in different rice backgrounds and also in Arabidopsis thaliana Our study paves a path for the use of a single gene to dramatically increase yield and shorten maturation time for crops, outcomes that promise to substantially increase world food security. © 2018 American Society of Plant Biologists. All rights reserved.

  12. The CMEMS-Med-MFC-Biogeochemistry operational system: implementation of NRT and Multi-Year validation tools

    NASA Astrophysics Data System (ADS)

    Salon, Stefano; Cossarini, Gianpiero; Bolzon, Giorgio; Teruzzi, Anna

    2017-04-01

    The Mediterranean Monitoring and Forecasting Centre (Med-MFC) is one of the regional production centres of the EU Copernicus Marine Environment Monitoring Service (CMEMS). Med-MFC manages a suite of numerical model systems for the operational delivery of the CMEMS products, providing continuous monitoring and forecasting of the Mediterranean marine environment. The CMEMS products of fundamental biogeochemical variables (chlorophyll, nitrate, phosphate, oxygen, phytoplankton biomass, primary productivity, pH, pCO2) are organised as gridded datasets and are available at the marine.copernicus.eu web portal. Quantitative estimates of CMEMS products accuracy are prerequisites to release reliable information to intermediate users, end users and to other downstream services. In particular, validation activities aim to deliver accuracy information of the model products and to serve as a long term monitoring of the performance of the modelling systems. The quality assessment of model output is implemented using a multiple-stages approach, basically inspired to the classic "GODAE 4 Classes" metrics and criteria (consistency, quality, performance and benefit). Firstly, pre-operational runs qualify the operational model system against historical data, also providing a verification of the improvements of the new model system release with respect to the previous version. Then, the near real time (NRT) validation aims at delivering a sustained on-line skill assessment of the model analysis and forecast, relying on the NRT available relevant observations (e.g. in situ, Bio Argo and satellite observations). NRT validation results are operated on weekly basis and published on the MEDEAF web portal (www.medeaf.inogs.it). On a quarterly basis, the integration of the NRT validation activities delivers a comprehensive view of the accuracy of model forecast through the official CMEMS validation webpage. Multi-Year production (e.g. reanalysis runs) follows a similar procedure, and the

  13. Recent results of the Global Precipitation Measurement (GPM) mission in Japan

    NASA Astrophysics Data System (ADS)

    Kubota, Takuji; Oki, Riko; Furukawa, Kinji; Kaneko, Yuki; Yamaji, Moeka; Iguchi, Toshio; Takayabu, Yukari

    2017-04-01

    The Global Precipitation Measurement (GPM) mission is an international collaboration to achieve highly accurate and highly frequent global precipitation observations. The GPM mission consists of the GPM Core Observatory jointly developed by U.S. and Japan and Constellation Satellites that carry microwave radiometers and provided by the GPM partner agencies. The GPM Core Observatory, launched on February 2014, carries the Dual-frequency Precipitation Radar (DPR) by the Japan Aerospace Exploration Agency (JAXA) and the National Institute of Information and Communications Technology (NICT). JAXA develops the DPR Level 1 algorithm, and the NASA-JAXA Joint Algorithm Team develops the DPR Level 2 and DPR-GMI combined Level2 algorithms. The Japan Meteorological Agency (JMA) started the DPR assimilation in the meso-scale Numerical Weather Prediction (NWP) system on March 24 2016. This was regarded as the world's first "operational" assimilation of spaceborne radar data in the NWP system of meteorological agencies. JAXA also develops the Global Satellite Mapping of Precipitation (GSMaP), as national product to distribute hourly and 0.1-degree horizontal resolution rainfall map. The GSMaP near-real-time version (GSMaP_NRT) product is available 4-hour after observation through the "JAXA Global Rainfall Watch" web site (http://sharaku.eorc.jaxa.jp/GSMaP) since 2008. The GSMaP_NRT product gives higher priority to data latency than accuracy, and has been used by various users for various purposes, such as rainfall monitoring, flood alert and warning, drought monitoring, crop yield forecast, and agricultural insurance. There is, however, a requirement for shortening of data latency time from GSMaP users. To reduce data latency, JAXA has developed the GSMaP realtime version (GSMaP_NOW) product for observation area of the geostationary satellite Himawari-8 operated by the Japan Meteorological Agency (JMA). GSMaP_NOW product was released to public in November 2, 2015 through the

  14. Determination for regional differences of agriculture using satellite data

    NASA Astrophysics Data System (ADS)

    Saito, G.

    2006-12-01

    Remote Sensing Laboratory, Field Science Center, Graduate School of Agriculture Science, Tohoku University starts at April 2004. For studies and education at the laboratory we are now developing the system of remote sensing and GIS. Earth Remote Sensing Data Analysis Center (ERSDAC) made the Home Pages of Terra/ASTER Image Web Library 3 "The Major Airport of the World." http://www.Ersdac.or.jp/ASTERimage3/library_E.html. First, we check the Airport Data to use agricultural understanding for the world. Almost major airport is located in rural area and surrounded with agriculture field. To survey the agriculture field adjacent to the major airport has almost the same condition of human activities. The images are same size and display about 18km X 14km. We can easily understand field size and surrounding conditions. We study seven airports as follows, 1. Tokyo Narita Airport (NRT), Japan, 2. Taipei Chiang kai Shek International Airport (TPE), Taiwan, 3. Bangkok International Airport (BKK), Thailand, 4. Riyadh King Khalid International Airport (RUH), Saudi Arabia, 5. Charles de Gaulle Airport (CDG), Paris, France, 6. Vienna International Airport (VIE), Austria, 7. Denver International Airport (DEN), CO, USA. At the area of Tokyo Narita Airport, there are many golf courses, big urban area and small size of agricultural fields. At Taipei Airport area are almost same as Tokyo Narita Airport area and there are many ponds for irrigations. Bangkok Airport area also has golf courses and many ponds for irrigation water. Riyadh Airport area is quite different from others, and there are large bare soils and small agriculture fields with irrigation and circle shape. Paris Airport area and Vienna Airport area are almost agricultural fields and there are vegetated field and bare soil fields because of crop rotation. Denver Airport area consists of almost agriculture fields and each field size is very large. The advantages of ASTER data are as follows, 1. High-resolution and large

  15. Bird Ingestion into Large Turbofan Engines

    DTIC Science & Technology

    1992-05-01

    4 JKT JAKARTA, INDONESIA 1 KCZ KOCHI,JAPAN 4 4 KIJ NIGATA,JAPAN 1 1 MYJ MATSUYAMA,JAPAN 2 2 NGO NAGOYA,JAPAN 2 1. 3 NRT TOKYO-NRT, JAPA-N 1 1 2...BL OEUOIj N H 1 G TODENT tip riP N I N NC 6 N iaNOMMN P112CR (lJnlE ;?Pi 1 1.4 N I HC N V:11 V 2 10I PR FO REPLED, 12? COWL RISETS FRrIPTTR 16 Nq...PRRPFHlH( 014 N 1 Nl N CU.4L I l1$0 N 1m V 2’ 1 NYC. 515 F C’L:ý O1110.PREPLITE IlINP. ID? LII N Vt’ 1 1 1: 0 LE CURL 140. V44F.PRF11O’:6 IARLLN 114

  16. Effect of sintering on transparent TiO2 18NR-T type thin films as the working electrode for transparent solar cells

    NASA Astrophysics Data System (ADS)

    Supriyanto, A.; Nandani; Wahyuningsih, S.; Ramelan, A. H.

    2018-03-01

    The working electrode based on semiconductor transparent TiO2 type 18NR-T for transparent solar cells have been grown by screen printing method. This study aim is to determine the effect of sintering on TiO2 thin films transparent as the working electrode of transparent solar cells. TiO2 films will be sintered at temperature 450°C, 500°C, 550°C and 600°C. TiO2 films optical properties were characterized using UV-Vis spectrophotometer, electrical properties were characterized using 4 point probemethods and the crystallization was characterized by X-Ray Diffraction (XRD). The lowest transmittance due to the treatment of annealing temperature variations is 550°C because the 550°C TiO2 layer is more absorbing. The peaks resulted from the annealing temperature treatment show that the high temperature the more anatase peaks. Characterization using four-point probe showed that the highest conductivity of TiO2 18NR-T thin film was 2.42 x 102 Ω-1m-1 at annealing temperature 550°C.

  17. Study protocol for a randomised trial of nicotine-free cigarettes as an adjunct to usual NRT-based cessation practice, in people who wish to stop smoking

    PubMed Central

    2011-01-01

    Background Current smoking cessation treatments focus on addressing the pharmacological dependence of smokers on nicotine. However, new strategies are needed that address both nicotine dependence and the psychological dependence on cigarettes as the source of nicotine. Evidence from a number of small smoking cessation studies suggests that the use of cigarettes with reduced nicotine content, in combination with nicotine replacement therapy (NRT), may help reduce withdrawal symptoms and increase quit rates. This paper describes the protocol for a large randomised-controlled trial to test the effect of using nicotine-free cigarettes together with NRT on long-term quit rates. Methods/design This single-blind, randomised trial aims to recruit 1,410 participants through the national telephone-based Quitline service in New Zealand. Participants in the treatment arm will be asked to stop smoking nicotine-containing cigarettes on their chosen Quit day and smoke ad libitum nicotine-free (Quest 3) cigarettes for six weeks. At the same time people in this group will be asked to start using NRT patches, gum and/or lozenges (as recommended by Quitline) for eight weeks. Participants in the control arm will be asked to stop smoking completely on their chosen Quit day and start using NRT patches, gum and/or lozenges (as recommended by Quitline) for eight weeks. Data collection will occur at baseline, three and six weeks, and three and six months after Quit day. The primary outcome is the proportion of participants who self-report seven-day point prevalence abstinence at six months since Quit date. Discussion Smoking prevalence in New Zealand has changed little in recent years (particularly in Māori, the indigenous people of New Zealand) and additional options for smokers who want to quit are needed. Although a variety of methods are available to help, many are expensive, have side effects, and despite their use most quit attempts still fail. This trial will test the balance of

  18. Atmospheric electron flux at airplane altitude

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Enomoto, R.; Chiba, J.; Ogawa, K.

    1991-12-01

    We have developed a new detector to systematically measure the cosmic-ray electron flux at airplane altitudes. We loaded a lead-glass-based electron telescope onto a commercial cargo airplane. The first experiment was carried out using the air route between Narita (Japan) and Sydney (Australia); during this flight we measured the electron flux at various altitudes and latitudes. The thresholds of the electron energies were 1, 2, and 4 GeV. The results agree with a simple estimation using one-dimensional shower theory. A comparison with a Monte Carlo calculation was made.

  19. The Impact of Long-Run CRAF Activation Risk on International Routes

    DTIC Science & Technology

    2011-06-01

    CRAF Stage II activations. United Airlines’ Los Angeles ( LAX ) to Tokyo, Japan (NRT) route scored a low .236, while the country risk for United in...0.5969 3.0173 16.5955 CO EWR MUC 0.0038 0.0213 3.0173 16.5955 UA LAX NRT 0.0333 0.2363 4.7173 28.4942 Route Risk Score Ranges - Low: 0 - .5...International Airport LAX – Los Angles International Airport ORD – Chicago O’Hare International Airport SFO – San Francisco International Airport

  20. Organization of projections from the anterior pole of the nucleus reticularis thalami (NRT) to subdivisions of the motor thalamus: light and electron microscopic studies in the rhesus monkey.

    PubMed

    Ilinsky, I A; Ambardekar, A V; Kultas-Ilinsky, K

    1999-07-05

    Projections to the motor-related thalamic nuclei from the anterior pole of the reticular thalamic nucleus (NRT) were studied after injections of biotinylated dextran amine and wheat germ agglutinin conjugated horseradish peroxidase at light and electron microscopic levels, respectively. Each injection resulted in anterograde labeling in the three subdivisions of the ventral anterior nucleus (pars parvicellularis, VApc; pars densicellularis, VAdc; and pars magnocellularis, VAmc) and in the ventral lateral nucleus (VL). NRT fibers had beaded shapes and coursed in a posterior direction giving rise to relatively diffuse terminal plexuses. The average size of the beads (0.7 microm2) and their density per 100 microm of fiber length (23.7-25.7) were similar between the nuclei studied. At the electron microscopic level, anterogradely labeled boutons displayed positive immunoreactivity for gamma-aminobutyric acid (GABA), contained pleomorphic synaptic vesicles, and formed relatively long (approximately 0.4 microm) symmetric synaptic contacts. Usually, a single terminal formed synapses on more than one postsynaptic structure. Synaptic contacts were on projection and local circuit neurons and targeted mainly their distal dendrites. In the VAmc, synapses on local circuit neurons composed 48% of the total sample, in the VAdc/VApc and in the VL the proportion was higher, 65% and 62%, respectively. The results suggest that the input from the anterior pole of the monkey reticular nucleus to the motor-related thalamic nuclei is organized differently from what is known on the organization of connections of NRT with sensory thalamic nuclei in other species in that the terminal fields of individual fibers are diffuse rather than focal and that at least 50% of synapses are established on GABAergic local circuit neurons.

  1. Japan.

    PubMed

    1987-02-01

    Japan is composed of 4 main islands and more than 3900 smaller islands and has 317.7 persons/square kilometer. This makes it one of the most densely populated nations in the world. Religion is an important force in the life of the Japanese and most consider themselves Buddhists. Schooling is free through junior high but 90% of Japanese students complete high school. In fact, Japan enjoys one of the highest literacy rates in the world. There are over 178 newspapers and 3500 magazines published in Japan and the number of new book titles issued each year is greater than that in the US. Since WW1, Japan expanded its influence in Asia and its holdings in the Pacific. However, as a direct result of WW2, Japan lost all of its overseas possessions and was able to retain only its own islands. Since 1952, Japan has been ruled by conservative governments which cooperate closely with the West. Great economic growth has come since the post-treaty period. Japan as a constitutional monarchy operates within the framework of a constitution which became effective in May 1947. Executive power is vested in a cabinet which includes the prime minister and the ministers of state. Japan is one of the most politically stable of the postwar democracies and the Liberal Democratic Party is representative of Japanese moderate conservatism. The economy of Japan is strong and growing. With few resources, there is only 19% of Japanese land suitable for cultivation. Its exports earn only about 19% of the country's gross national product. More than 59 million workers comprise Japan's labor force, 40% of whom are women. Japan and the US are strongly linked trading partners and after Canada, Japan is the largest trading partner of the US. Foreign policy since 1952 has fostered close cooperation with the West and Japan is vitally interested in good relations with its neighbors. Relations with the Soviet Union are not close although Japan is attempting to improve the situation. US policy is based on

  2. Japan.

    PubMed

    1989-02-01

    Japan consists of 3900 islands and lies off the east coast of Asia. Even though Japan is one of the most densely populated nations in the world, its growth rate has stabilized at .5%. 94% of all children go to senior high school and almost 90% finish. Responsibility for the sick, aged, and infirmed is changing from the family and private sector to government. Japan was founded in 600 BC and its 1st capital was in Nara (710-1867). The Portuguese, the 1st Westerners to make contact with Japan in 1542, opened trade which lasted until the mid 17th century. US Navy Commodore Matthew Perry forced Japan to reopen in 1854. Following wars with China and Russia in the late 1800s and early 1900s respectively, Japan took part in World Wars I and II. In between these wars Japan invaded Manchuria and China. The US dropped an atomic bomb on Hiroshima and Nagasaki and the Japanese surrendered in September, 1945 ending World War II (WWII). Following, WWII, the Allied Powers guided Japan's establishment as a nonthreatening nation and a democratic parliamentary government (a constitutional monarchy) with a limited defense force. Japan remains one of the most politically stable of all postwar democracies. The Liberal Democratic Party's Noboru Takeshita became prime minister in 1987. Japan has limited natural resources and only 19% of the land is arable. Japanese ingenuity and skill combine to produce one of the highest per hectare crop yields in the world. Japan is a major economic power, and its and the US economies are becoming more interdependent. Its exports, making up only 13% of the gross national product, mainly go to Canada and the US. Many in the US are concerned, however, with the trade deficit with Japan and are seeking ways to make trade more equitable. Japan wishes to maintain good relations with its Asian neighbors and other nations. The US and Japan enjoy a strong, productive relationship.

  3. A randomized clinical trial of a financial education intervention with nicotine replacement therapy (NRT) for low socio-economic status Australian smokers: a study protocol.

    PubMed

    Courtney, Ryan J; Bradford, Deborah; Martire, Kristy A; Bonevski, Billie; Borland, Ron; Doran, Christopher; Hall, Wayne; Farrell, Michael; Siahpush, Mohammad; Sanson-Fisher, Rob; West, Robert; Mattick, Richard P

    2014-10-01

    Reducing smoking prevalence among smokers from low socio-economic status (SES) is a preventative health priority. Financial stress (e.g. shortage of money or inability to pay bills) may be a major barrier to quitting smoking. This study evaluates the efficacy of a financial education and support programme coupled with pharmacotherapy at improving cessation rates at 8-month follow-up among Australian low SES smokers (people receiving a government pension or allowance). A two-group parallel block randomized (ratio 1 : 1) open-label clinical trial (RCT) with allocation concealment will be conducted. Allocation will be concealed to interviewers at data collection-points. The study will be conducted primarily by telephone with baseline, follow-up interviews and telephone-based support sessions. Nicotine replacement therapy (NRT) delivery will be mail-based. Daily smokers who are interested in quitting smoking and are currently in receipt of government benefits (n = 1046) will be recruited through study advertisements placed in newspapers, posters placed in government social assistance agencies and Quitline telephone-based cessation support services. After completion of a baseline computer-assisted telephone interview, participants will be allocated randomly to control or intervention group using a permuted block approach. Participants in both groups will receive 8 weeks of free combination NRT plus Quitline support. Participants in the intervention group will also receive four telephone-delivered financial education and support sessions. The primary outcome measure will be prolonged abstinence (at 8-month follow-up) assessed using Russell Standard criteria and biochemically verified (urine cotinine). This is the first intervention study to evaluate the potential of co-managing financial stress as a means of enhancing smokers' capacity to quit smoking. Such an intervention may provide a scalable intervention to help low SES smokers to quit. © 2014 Society for

  4. Japan.

    ERIC Educational Resources Information Center

    Geiger, Rita; And Others

    The document offers practical and motivating techniques for studying Japan. Dedicated to promoting global awareness, separate sections discuss Japan's geography, history, culture, education, government, economics, energy, transportation, and communication. Each section presents a topical overview; suggested classroom activities; and easily…

  5. Fluorescent sensors for activity and regulation of the nitrate transceptor CHL1/NRT1.1 and oligopeptide transporters

    PubMed Central

    Ho, Cheng-Hsun; Frommer, Wolf B

    2014-01-01

    To monitor nitrate and peptide transport activity in vivo, we converted the dual-affinity nitrate transceptor CHL1/NRT1.1/NPF6.3 and four related oligopeptide transporters PTR1, 2, 4, and 5 into fluorescence activity sensors (NiTrac1, PepTrac). Substrate addition to yeast expressing transporter fusions with yellow fluorescent protein and mCerulean triggered substrate-dependent donor quenching or resonance energy transfer. Fluorescence changes were nitrate/peptide-specific, respectively. Like CHL1, NiTrac1 had biphasic kinetics. Mutation of T101A eliminated high-affinity transport and blocked the fluorescence response to low nitrate. NiTrac was used for characterizing side chains considered important for substrate interaction, proton coupling, and regulation. We observed a striking correlation between transport activity and sensor output. Coexpression of NiTrac with known calcineurin-like proteins (CBL1, 9; CIPK23) and candidates identified in an interactome screen (CBL1, KT2, WNKinase 8) blocked NiTrac1 responses, demonstrating the suitability for in vivo analysis of activity and regulation. The new technology is applicable in plant and medical research. DOI: http://dx.doi.org/10.7554/eLife.01917.001 PMID:24623305

  6. Nrt1 and Tna1-independent export of NAD+ precursor vitamins promotes NAD+ homeostasis and allows engineering of vitamin production.

    PubMed

    Belenky, Peter; Stebbins, Rebecca; Bogan, Katrina L; Evans, Charles R; Brenner, Charles

    2011-05-11

    NAD(+) is both a co-enzyme for hydride transfer enzymes and a substrate of sirtuins and other NAD(+) consuming enzymes. NAD(+) biosynthesis is required for two different regimens that extend lifespan in yeast. NAD(+) is synthesized from tryptophan and the three vitamin precursors of NAD(+): nicotinic acid, nicotinamide and nicotinamide riboside. Supplementation of yeast cells with NAD(+) precursors increases intracellular NAD(+) levels and extends replicative lifespan. Here we show that both nicotinamide riboside and nicotinic acid are not only vitamins but are also exported metabolites. We found that the deletion of the nicotinamide riboside transporter, Nrt1, leads to increased export of nicotinamide riboside. This discovery was exploited to engineer a strain to produce high levels of extracellular nicotinamide riboside, which was recovered in purified form. We further demonstrate that extracellular nicotinamide is readily converted to extracellular nicotinic acid in a manner that requires intracellular nicotinamidase activity. Like nicotinamide riboside, export of nicotinic acid is elevated by the deletion of the nicotinic acid transporter, Tna1. The data indicate that NAD(+) metabolism has a critical extracellular element in the yeast system and suggest that cells regulate intracellular NAD(+) metabolism by balancing import and export of NAD(+) precursor vitamins.

  7. Tokyo, Japan

    NASA Technical Reports Server (NTRS)

    1981-01-01

    Tokyo, (35.5N, 140.0E) the capital city of Japan, Tokyo Bay and the neighboring cities of Yokohama, Kawasaki and Chiba are seen in this view of Japan. This great international seaport facility covers almost all of the bayfront and is home to over thirty million people.

  8. Reconsidering Japan's underperformance in pharmaceuticals: evidence from Japan's anticancer drug sector.

    PubMed

    Umemura, Maki

    2010-01-01

    Unlike its automobile or electronics industries, Japan's pharmaceutical industry did not become a global leader. Japan remains a net importer of pharmaceuticals and has introduced few global blockbuster drugs. Alfred Chandler argued that Japan's pharmaceutical firms remained relatively weak because Western firms enjoyed an insurmountable first first-mover advantage. However, this case study of the anticancer drug sector illustrates that Chandler's explanation is incomplete. Japanese medical culture, government policy, and research environment also played a substantial role in shaping the industry. In the 1970s and 1980s, these factors encouraged firms to develop little few effective drugs with low side effects, and profit from Japan's domestic market. But, these drugs were unsuitable to foreign markets with more demanding efficacy standards. As a result, Japan not only lost more than a decade in developing ineffective drugs, but also neglected to create the infrastructure necessary to develop innovative drugs and build a stronger pharmaceutical industry.

  9. 21 CFR 186.1555 - Japan wax.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Japan wax. 186.1555 Section 186.1555 Food and Drugs... Substances Affirmed as GRAS § 186.1555 Japan wax. (a) Japan wax (CAS Reg. No. 8001-39-6), also known as Japan... fruits of the oriental sumac, Rhus succedanea (Japan, Taiwan, and Indo-China), R. vernicifera (Japan...

  10. Academic Libraries in Japan

    ERIC Educational Resources Information Center

    Cullen, Rowena; Nagata, Haruki

    2008-01-01

    Academic libraries in Japan are well resourced by international standards, and support Japan's internationally recognized research capability well, but there are also ways in which they reflect Japan's strong bureaucratic culture. Recent changes to the status of national university libraries have seen a new interest in customer service, and…

  11. Japan's funding supremo

    NASA Astrophysics Data System (ADS)

    Durrani, Matin

    2018-02-01

    Yasuhiro Iye, a condensed-matter physicist who is executive director of the Japan Society for the Promotion of Science, talks to Matin Durrani about the pressures and challenges facing Japan's biggest funding agency

  12. Japan: Shikoku Island

    Atmospheric Science Data Center

    2016-08-24

    ... and island stations in the waters surrounding Japan and Korea. They characterized meteorological conditions, measured the atmospheric ... flew overhead. These MISR images, centered just north of Shikoku Island in southwest Japan, were acquired on April 13, 2001 ...

  13. Physics in Japan

    NASA Astrophysics Data System (ADS)

    Khan, Sameen Ahmed

    2018-04-01

    I read your Japan special report with a keen interest. My first visit to Japan was in March 1994 to attend the JSPS-KEK International Spring School: High Energy Ion Beams – Novel Beam Techniques and their Applications.

  14. Japan's aging economics.

    PubMed

    Ezrati, M

    1997-01-01

    "Japan's population is aging faster than that of any other country in the world. The unprecedented increase in retirees relative to the size of Japan's work force will force radical change if the nation is to avoid a fiscal crisis, or worse. These seemingly innocent demographic changes will force Japan to shrink its famously high savings rate, reverse its proud trade surplus, send more industry overseas, liberalize its tightly controlled markets, and take on a more active, high-profile foreign policy. Ultimately, these changes will shift the balance of power in East Asia." excerpt

  15. 21 CFR 186.1555 - Japan wax.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... fruits of the oriental sumac, Rhus succedanea (Japan, Taiwan, and Indo-China), R. vernicifera (Japan), and R. trichocarpa (China, Indo-China, India, and Japan). Japan wax is soluble in hot alcohol, benzene...

  16. 21 CFR 186.1555 - Japan wax.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... fruits of the oriental sumac, Rhus succedanea (Japan, Taiwan, and Indo-China), R. vernicifera (Japan), and R. trichocarpa (China, Indo-China, India, and Japan). Japan wax is soluble in hot alcohol, benzene...

  17. 21 CFR 186.1555 - Japan wax.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... fruits of the oriental sumac, Rhus succedanea (Japan, Taiwan, and Indo-China), R. vernicifera (Japan), and R. trichocarpa (China, Indo-China, India, and Japan). Japan wax is soluble in hot alcohol, benzene...

  18. Nrt1 and Tna1-Independent Export of NAD+ Precursor Vitamins Promotes NAD+ Homeostasis and Allows Engineering of Vitamin Production

    PubMed Central

    Belenky, Peter; Stebbins, Rebecca; Bogan, Katrina L.; Evans, Charles R.; Brenner, Charles

    2011-01-01

    NAD+ is both a co-enzyme for hydride transfer enzymes and a substrate of sirtuins and other NAD+ consuming enzymes. NAD+ biosynthesis is required for two different regimens that extend lifespan in yeast. NAD+ is synthesized from tryptophan and the three vitamin precursors of NAD+: nicotinic acid, nicotinamide and nicotinamide riboside. Supplementation of yeast cells with NAD+ precursors increases intracellular NAD+ levels and extends replicative lifespan. Here we show that both nicotinamide riboside and nicotinic acid are not only vitamins but are also exported metabolites. We found that the deletion of the nicotinamide riboside transporter, Nrt1, leads to increased export of nicotinamide riboside. This discovery was exploited to engineer a strain to produce high levels of extracellular nicotinamide riboside, which was recovered in purified form. We further demonstrate that extracellular nicotinamide is readily converted to extracellular nicotinic acid in a manner that requires intracellular nicotinamidase activity. Like nicotinamide riboside, export of nicotinic acid is elevated by the deletion of the nicotinic acid transporter, Tna1. The data indicate that NAD+ metabolism has a critical extracellular element in the yeast system and suggest that cells regulate intracellular NAD+ metabolism by balancing import and export of NAD+ precursor vitamins. PMID:21589930

  19. Barbarian medicine in feudal Japan.

    PubMed

    Fodstad, Harald; Hariz, Marwan I; Hirabayashi, Hidehiro; Ohye, Chihiro

    2002-10-01

    THE FIRST EUROPEANS to discover Japan were Portuguese traders who arrived in 1542. Fifteen years later, the Portuguese Jesuit priest and surgeon Luis De Almeida (1525-1583) founded the first Western hospital in Japan, for the care of lepers, syphilitics, and orphans. Because the hospital had a negative influence on the spread of Christianity, the Jesuits closed it in 1586. During the Tokugawa Shogunate (1600-1868), when Japan was secluded from the rest of the world, the only foreign physicians allowed to enter Japan were those employed by the Dutch factory at Dejima in Nagasaki. Only four of those physicians left behind seeds for the foundation of Western medicine in Japan, namely Caspar Schambergen, who founded a Japanese school of surgery in 1650; Engelbert Kämpfer, who visited Japan in 1691 to 1692; Carl Peter Thunberg, who botanically explored Japan in 1775 to 1776; and Philipp Franz Balthasar von Siebold, who practiced medicine in Nagasaki in 1823 to 1829 and 1859 to 1861. On the whole, Western medicine and surgery never established a real foothold in Japan until the fall of the shogunate and the restoration of the emperor in 1868.

  20. Japan Report

    DTIC Science & Technology

    1985-03-18

    increased profitability, productivity and more effective management ." Members of the British side also called for an increase in Japan’s defense...copyright transfer, or rental permission is called technology trade. According to the Statistic Bureau of the Management and Coordina- tion Agency...1- 8.8 -Swizerland 6.3 5.6 Others 13.1 Source: Statistics Bureau of the Management and Coordination Agency China. 66.2% of Japan’s imported

  1. Industrial lasers in Japan

    NASA Astrophysics Data System (ADS)

    Karube, Norio

    1991-03-01

    I am to report on some aspects of industrial lasers in Japan. Mostly centering on the market. In Japan, the history of laser developnent is rather profound. And long. Ever since the first invention of the laser in this country in 1960. This is partly because of the fact that in Japan the spectroscopic studies of the ruby was very popular in the late 1950's. Ever since niost of the work has been done in the research laboratories of the industry, not in the universities or not in the governmental laboratories. And since that time our first activity was mainly centering on the basic research, but after that time we have the evolution of the technology. One of the features in Japan is that the activity of developement and research of laser technology from the very basic phase up to the present commercialization has been done by the same group of people, including ine. We had a national project which ended about six years ago which was sponsored by MITI. MITI is Ministry of International Trade and Industry in Japan. And because of this national project, the effect of this project had a very enlightening effect in Japan. And after that our Japanese laser market became very flourishing.

  2. Japan Report.

    DTIC Science & Technology

    1987-02-03

    of Keidanren’s U.S. Investment Mission, who is also vice chairman of the Industrial Bank of Japan; Mamoru Sakai, leader of the B Group of...Keidanren’s U.S. Investment Mission, who is also a director of the Japan Long-Term Credit Bank ; Masayoshi Tozaki, leader of the C Group of Keidanren’s U.S...Constitution. At the same time, Federal Reserve Bank Chairman Volcker has repeatedly stressed that maintaining the value of the dollar is essential. In

  3. Japan: Teaching Units.

    ERIC Educational Resources Information Center

    Hadley, Marilyn, Ed.; And Others

    This teaching guide was developed by undergraduate elementary education students as part of the requirements for a social studies methods course. The guide presents nine teaching units about various aspects of Japan. The unit topics range from the broad to the specific, and reflect a variety of approaches for teaching about Japan in the public…

  4. Japan's High Schools.

    ERIC Educational Resources Information Center

    Rohlen, Thomas P.

    The author, an anthropologist, spent 14 months (1974-75) in the industrial port city of Kobe (Japan) observing a cross section of urban high schools, including Japan's most elite private school and a night vocational school plagued by absenteeism and delinquency. He reports on the character of the institutions and of the experience via…

  5. Microelectronics in Japan

    NASA Astrophysics Data System (ADS)

    Boulton, William R.

    1995-02-01

    The purpose of this JTEC study is to evaluate Japan's electronic manufacturing and packaging capabilities within the context of global economic competition. To carry out this study, the JTEC panel evaluated the framework of the Japanese consumer electronics industry and various technological and organizational factors that are likely to determine who will win and lose in the marketplace. This study begins with a brief overview of the electronics industry, especially as it operates in Japan today. Succeeding chapters examine the electronics infrastructure in Japan and take an in-depth look at the central issues of product development in order to identify those parameters that will determine future directions for electronic packaging technologies.

  6. Microelectronics in Japan

    NASA Technical Reports Server (NTRS)

    Boulton, William R.

    1995-01-01

    The purpose of this JTEC study is to evaluate Japan's electronic manufacturing and packaging capabilities within the context of global economic competition. To carry out this study, the JTEC panel evaluated the framework of the Japanese consumer electronics industry and various technological and organizational factors that are likely to determine who will win and lose in the marketplace. This study begins with a brief overview of the electronics industry, especially as it operates in Japan today. Succeeding chapters examine the electronics infrastructure in Japan and take an in-depth look at the central issues of product development in order to identify those parameters that will determine future directions for electronic packaging technologies.

  7. Globalization and Education in Japan

    ERIC Educational Resources Information Center

    Ohkura, Kentaro; Shibata, Masako

    2009-01-01

    In this paper, the authors contend that globalization in Japan is the gradual process in which Japan's positioning of "self" within international relations, which had formerly been dominated by the West, has changed. Accordingly, Japan's relationships with the West and the rest of the world, for example, Asia, have also been reviewed and…

  8. Discontinuation of nicotine replacement therapy among smoking-cessation attempters.

    PubMed

    Burns, Emily K; Levinson, Arnold H

    2008-03-01

    Nicotine replacement therapy (NRT) doubles successful quitting, but more than half of NRT users do not comply with optimal treatment regimens. From the 2005 Colorado state tobacco survey, quit attempters who utilized NRT (N=366) were analyzed in spring 2007. Descriptive and regression analyses were used to examine reasons for discontinuing NRT, length of time on NRT, and quit intentions. The reasons for discontinuing NRT were resuming smoking (34%), side effects (17%), NRT not helping with quitting (14%), quitting smoking (10%), and cost (5%). Poverty, age, and non-Latino minority status were associated with reasons for discontinuation other than quitting smoking. Having side effects was associated with a short duration of NRT use and 95% lower odds of intending to quit in the next month. In the first population-level study examining reasons for discontinuing NRT, general-population smokers who initiate NRT use when attempting to quit are highly likely to discontinue NRT prematurely. Age and culturally-appropriate medication management interventions may increase NRT compliance and improve cessation outcomes.

  9. Free Resources for Teaching about Japan. Revised Edition.

    ERIC Educational Resources Information Center

    Wojtan, Linda S.

    A collection of sources of information about Japan and resource materials available for teaching about Japan are included in this document. Part one, "Who and Where" lists names and addresses from a variety of sources including the Embassy and Consulates General of Japan, the Japan Foundation, Japan Trade Centers (Japan External Trade…

  10. Tohoku Tsunami Debris, Japan

    NASA Image and Video Library

    2011-06-14

    The Mar. 11, 2011, Tohoku, Japan earthquake and tsunami devastated a large extent of the northeastern Japan coast, and virtually erased many villages and cities from the map. NASA Terra spacecraft acquired this image of Sendai on Mar. 14, 2011.

  11. FBIS report. Science and technology: Japan, December 10, 1996

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1996-12-10

    Contents (partial): Japan: Fabrication of Diamond Single Crystal Thin Film by Ion Beam Deposition; Japan: Hitachi Metal Develops New Semi Solid Metal Processing Technology; Japan: NTT Develops Fuel Cell System That Uses Both City Gas, LPG; Japan: Daihatsu Motor Completes Prototype EV; Japan: NIRIM Announces Success With Synthetic Bone Development; Japan: Sandoz Pharmaceuticals Plans Clinical Trials of Gene Therapy to Cerebral Tumor in Japan; Japan: MITI To Provide Aid for Residential Solar Power Generation Systems; Japan: MELCO To Provide Satellite Solar Cell Panel for SSL, USA; Japan: Japan Atomic Energy Research Institute Leads Nuclear Research; Japan: Kobe Steel`s Superconducting Magnetmore » Ready to Go Fast; Japan: MPT To Begin Validation Test for Electric Money Implementation; and Japan: Defense Agency to Send ASDF`s Pilots to Russia for Training.« less

  12. [Building epilepsy care network in Japan].

    PubMed

    Otsuki, Taisuke

    2012-01-01

    Number of epilepsy patient in Japan officially surveyed by our government in 2008 is 219,000, which is only 0.17% of the total population and less than one third of the prevalence rate reported in Western countries. Number of epilepsy surgery per year in Japan is also low and less than half of other countries such as US, UK and Korea. These numbers may suggest that epilepsy care in Japan is not sufficient to cover all hidden medical needs of people with epilepsy at present. To solve this issue, our research group funded by the government have started to build an epilepsy care network among primary care physicians, secondary care neurology specialists and tertiary care epilepsy centers by utilizing a web site: Epilepsy Care Network-Japan (http://www.ecn-japan.com/) from July 2012. We are also proposing an epilepsy care algorithm suitable for our complex medical community consisted with various neurology specialists such as pediatric and adult neurologists, neurosurgeons and psychiatrists. Building Epilepsy Care Network in Japan may facilitate better medical and social support for people with epilepsy in Japan.

  13. Predicting intention to use nicotine replacement therapy in people attending residential treatment for substance dependency.

    PubMed

    Kelly, Peter J; Townsend, Camilla J; Osborne, Briony A; Baker, Amanda L; Deane, Frank P; Keane, Carol; Ingram, Isabella; Lunn, Joanne

    2018-02-28

    Nicotine Replacement Therapy (NRT) is recommended as a frontline smoking cessation tool for people attending mental health and substance dependence treatment services. Previous research suggests that NRT is underutilized in these settings. To improve the use of NRT amongst people attending residential treatment for substance use disorders (SUDs) it is important that the factors influencing smokers' decisions to use NRT are understood. The study aimed to examine: (1) smoking cessation strategies used by participants in previous quit attempts, (2) participants' attitudes towards NRT (i.e. safety concerns and perceived efficacy), and (3) the predictors of participants' intention to use NRT to support future quit attempts. Participants completed a cross-sectional survey that examined their smoking behaviours, previous experiences using smoking cessation strategies, attitudes and beliefs regarding NRT, and intention to use NRT as part of future quit attempts (N = 218). All participants were attending residential treatment for substance use disorders provided by We Help Ourselves (WHOS), a large provider of specialist alcohol and other drug treatment in Australia. The majority of respondents (98%) reported that they had smoked regularly in their lifetime, and 89% were current smokers. Forty-five percent of the current smokers reported that they had previously used NRT to support a quit attempt, with 54% reporting that they intended to use NRT to support a future quit attempt. Intentions to use NRT were not related to the participants' mental health status or the participants' perceptions regarding the safety or potential drawbacks associated with using NRT. However, participants were more likely to report that they would use NRT to support future quit attempts if they were female, had previously used NRT and perceived NRT to be effective. Improving the use of evidence based smoking cessation strategies within substance use treatment continues to be a priority. To enhance

  14. Characteristics of Wet Deposition in Japan

    NASA Astrophysics Data System (ADS)

    Iwasaki, A.; Arakaki, T.

    2017-12-01

    Acid deposition survey in Japan has started since 1991 by Japan Environmental Laboratories Association (JELA). The JELA has about 60 monitoring sites for wet deposition including remote, rural and urban area. The measured constituents of wet deposition are; precipitation, pH, electric conductivity, major Anions, and major Cations. From those data, we analyze spatial and temporal variations of wet deposition components in Japan. Among the 60 monitoring sites, 39 sampling sites were selected in this study, which have kept sampling continuously between 2003JFY and 2014JFY. All samples were collected by wet-only samplers. To analyze area characteristics, all the areas were divided into 6 regions; Northern part of Japan (NJ), Facing the Japan Sea (JS), Eastern part of Japan (EJ), Central part of Japan (CJ), Western part of Japan (WJ) and Southern West Islands (SW). NO3- and non-sea-salt-SO42- (nss-SO42-) are major components of rain acidification. Especially, between December and February (winter) the air mass from west affected the temporal variations of those acid components and the concentrations were higher in JS and WJ regions than those in other regions. Japanese ministry of the Environment reported that mixing ratio of NO2 in Japan has been less than 0.04ppm since 1976, and that of SO2 has been less than 0.02ppm since 1978. Their concentrations in Japan have remained flat or slowly decreased recently. However the temporal variations of NO3-/nss-SO42- ratio in winter in JS region were significantly increased on average at 2.2% y-1 from 2003JFY to 2014JFY. The results suggest that long-range transboundary air pollutants increased NO3- concentrations and NO3-/nss-SO42- ratio.

  15. Advances in food composition tables in Japan-Standard Tables Of Food Composition in Japan - 2015 - (Seventh Revised Edition).

    PubMed

    Watanabe, Tomoko; Kawai, Ryoko

    2018-01-01

    The latest version of the Standard Tables of Food Composition in Japan-2015- comprises the main food composition table (Standard Tables of Food Composition in Japan-2015-[Seventh revised Edition)) and three supplementary books. The supplementary books are Standard Tables of Food Composition in Japan - 2015 - (Seventh Revised Edition) - Amino Acids -, Standard Tables of Food Composition in Japan - 2015 - (Seventh Revised Edition) - Fatty Acids - and Standard Tables of Food Composition in Japan - 2015 - (Seventh Revised Edition) - Available Carbohydrates, Polyols and Organic Acids-. We believe understanding these food composition tables can give greater insight into Japan's gastronomic culture and changes in eating habits. We expect them to play important roles as part of the East Asia food composition tables. Copyright © 2017. Published by Elsevier Ltd.

  16. Japan's electronic packaging technologies

    NASA Technical Reports Server (NTRS)

    Tummala, Rao R.; Pecht, Michael

    1995-01-01

    The JTEC panel found Japan to have significant leadership over the United States in the strategic area of electronic packaging. Many technologies and products once considered the 'heart and soul' of U.S. industry have been lost over the past decades to Japan and other Asian countries. The loss of consumer electronics technologies and products is the most notable of these losses, because electronics is the United States' largest employment sector and is critical for growth businesses in consumer products, computers, automobiles, aerospace, and telecommunications. In the past there was a distinction between consumer and industrial product technologies. While Japan concentrated on the consumer market, the United States dominated the industrial sector. No such distinction is anticipated in the future; the consumer-oriented technologies Japan has dominated are expected to characterize both domains. The future of U.S. competitiveness will, therefore, depend on the ability of the United States to rebuild its technological capabilities in the area of portable electronic packaging.

  17. High definition systems in Japan

    NASA Technical Reports Server (NTRS)

    Elkus, Richard J., Jr.; Cohen, Robert B.; Dayton, Birney D.; Messerschmitt, David G.; Schreiber, William F.; Tannas, Lawrence E., Jr.; Shelton, Duane

    1991-01-01

    The successful implementation of a strategy to produce high-definition systems within the Japanese economy will favorably affect the fundamental competitiveness of Japan relative to the rest of the world. The development of an infrastructure necessary to support high-definition products and systems in that country involves major commitments of engineering resources, plants and equipment, educational programs and funding. The results of these efforts appear to affect virtually every aspect of the Japanese industrial complex. The results of assessments of the current progress of Japan toward the development of high-definition products and systems are presented. The assessments are based on the findings of a panel of U.S. experts made up of individuals from U.S. academia and industry, and derived from a study of the Japanese literature combined with visits to the primary relevant industrial laboratories and development agencies in Japan. Specific coverage includes an evaluation of progress in R&D for high-definition television (HDTV) displays that are evolving in Japan; high-definition standards and equipment development; Japanese intentions for the use of HDTV; economic evaluation of Japan's public policy initiatives in support of high-definition systems; management analysis of Japan's strategy of leverage with respect to high-definition products and systems.

  18. Current Status of Doping in Japan Based on Japan Anti-Doping Disciplinary Panels of the Japan Anti-Doping Agency (JADA): A Suggestion on Anti-Doping Activities by Pharmacists in Japan.

    PubMed

    Imanishi, Takashi; Kawabata, Takayoshi; Takayama, Akira

    2017-01-01

    In 2009, the Japan Anti-Doping Agency (JADA) established the "Sports Pharmacist Accreditation Program" to prevent doping in sports. Since then, anti-doping activities in Japan have been attracting attention. In this study, we investigated research about the current status of doping from 2007 to 2014 in Japan to make anti-doping activities more concrete, and we also discussed future anti-doping activities by pharmacists. In Japan, bodybuilding was the sporting event with the highest number and rate of doping from 2007 to 2014. Many of the positive doping cases were detected for class S1 (anabolic agents), S5 (diuretics and masking agents), and S6 (stimulants). Within class S1, supplements were the main cause of positive doping. Within class S5, medicines prescribed by medical doctors were the main cause of positive doping. Within class S6, non-prescription medicines (e.g., OTC) were the main cause of positive doping. When we looked at the global statistics on doping, many of the positive doping cases were detected for class S1. On comparing the Japanese statistics with the global statistics, the rate of positive doping caused by class S1 was significantly lower, but that caused by classes S5 and S6 was significantly higher in Japan than in the world. In conclusion, pharmacists in Japan should pay attention to class S1, S5, and S6 prohibited substances and to the sport events of bodybuilding. Based on this study, sports pharmacists as well as common pharmacists should suggest new anti-doping activities to prevent doping in the future.

  19. Japan's advanced medicine.

    PubMed

    Sho, Ri; Narimatsu, Hiroto; Murakami, Masayasu

    2013-10-01

    Like health care systems in other developed countries, Japan's health care system faces significant challenges due to aging of the population and economic stagnation. Advanced medicine (Senshin Iryou) is a unique system of medical care in Japan offering highly technology-driven medical care that is not covered by public health insurance. Advanced medicine has recently developed and expanded as part of health care reform. Will it work? To answer this question, we briefly trace the historical development of advanced medicine and describe the characteristics and current state of advanced medical care in Japan. We then offer our opinions on the future of advanced medicine with careful consideration of its pros and cons. We believe that developing advanced medicine is an attempt to bring health care reform in line rather than the goal of health care reform.

  20. Dust over Japan

    NASA Image and Video Library

    2017-12-08

    March 24, 2010 - Dust over Japan This image of gray/brown dust being blown over Japan was captured on March 21, 2010 by the MODIS on the Terra satellite. On the left is the Korean peninsula. Japan stretches diagonally across the image, up to the top right corner. The dust is likely from the sandstorm that swept across the China the previous day. The sand and dust originated from the south and east of Inner Mongolia. In this image from March 20, the dust is nearly obscuring the Bohai Sea, which is just west of the Korean peninsula. Here is a handy map. For more information related to this image go to: modis.gsfc.nasa.gov/gallery/individual.php?db_date=2010-0... For more information about Goddard Space Flight Center go here: www.nasa.gov/centers/goddard/home/index.html

  1. Medicinal Nicotine Nonuse: Smokers’ Rationales for Past Behavior and Intentions to Try Medicinal Nicotine in a Future Quit Attempt

    PubMed Central

    2013-01-01

    Introduction: Nicotine replacement therapy (NRT) is a proven smoking cessation treatment. Previous research has reported low rates of NRT use among quit attempters. This study analyzed population-level nonuse rates and reasons for not using NRT. Methods: Data were from the 2008 adult Colorado Tobacco Attitudes and Behaviors Survey (TABS), a population-based, random-digit-dialed telephone survey (n = 14,156). Primary measures were past NRT nonuse and future intentions regarding NRT use among current smokers intending to quit. Multiple logistic regression was used to identify reasons for past NRT nonuse associated with intention to use NRT in the future, adjusted for factors known to influence NRT use. Results: Nearly, 80% of 1,095 current smokers who intended to quit had never used NRT. The most common reasons for nonuse were belief that “willpower” alone is sufficient for cessation (21.5%), perceived lack of NRT effectiveness (15.6%), and cost (14.3%). Willpower was more widely reported among Hispanics than Anglos (36.9% vs. 14.7%) and nondaily versus daily smokers (30.4% vs. 12.5%). Most previous NRT nonusers reported they would use cold turkey (65.2%) in their next quit attempt; NRT was the next most common choice (15.0%). In multivariate analysis, smokers identifying cost or willpower as a reason for previous nonuse had significantly lower odds of planning to use NRT in a future quit attempt. Conclusions: The majority of smokers have never used NRT and do not plan to use it in the future. Cost and belief in willpower alone are significant barriers to using NRT in future smoking cessation attempt. PMID:23817584

  2. Groundwater contamination in Japan

    NASA Astrophysics Data System (ADS)

    Tase, Norio

    1992-07-01

    Problems on groundwater contamination in Japan are briefly summarized in this paper. Although normal physical conditions in Japan restrict the possibilities of groundwater contamination, human activities are threatening groundwater resources. A survey by the Environment Agency of Japan showed nationwide spreading of organic substances, such as trichloroethylene as well as nitrogen compounds. Synthetic detergents have also been detected even in rural areas and in deep confined aquifers, although their concentrations are not as high. Public awareness of agrichemical or pesticides abuse, especially from golf courses, is apparent. Other problems such as nitrate-nitrogen, leachate from landfills, and the leaking of underground storage tanks are also discussed.

  3. Recent meteor observing activities in Japan

    NASA Astrophysics Data System (ADS)

    Yamamoto, M.

    2005-02-01

    The meteor train observation (METRO) campaign is described as an example of recent meteor observing activity in Japan. Other topics of meteor observing activities in Japan, including Ham-band radio meteor observation, the ``Japan Fireball Network'', the automatic video-capture software ``UFOCapture'', and the Astro-classroom programme are also briefly introduced.

  4. A Cultural Experience: Japan.

    ERIC Educational Resources Information Center

    Wood, Robert W.; And Others

    This activities unit for teaching about Japan is designed for use with elementary students. The activities reflect the growing importance of Japan in today's world, and the belief that the social studies curriculum should reflect principles of global education. The unit is intended to explore seven major goals included in the social studies…

  5. Teaching about Japan: Lessons and Resources.

    ERIC Educational Resources Information Center

    Bernson, Mary Hammond, Ed.; Wojtan, Linda S., Ed.

    This document is a revised and updated version of two publications: "Modern Japan: An Idea Book for K-12 Teachers" and "Resources for Teaching About Japan." These lesson plans were developed by teachers who participated in a summer institute on Japan, sponsored by the East Asia Resource Center at the Jackson School of…

  6. Alleviation of proton toxicity by nitrate uptake specifically depends on nitrate transporter 1.1 in Arabidopsis.

    PubMed

    Fang, Xian Zhi; Tian, Wen Hao; Liu, Xing Xing; Lin, Xian Yong; Jin, Chong Wei; Zheng, Shao Jian

    2016-07-01

    Protons in acid soil are highly rhizotoxic to plants, but the mechanism of tolerance of plants to protons is largely unknown. Nitrate uptake by root cells is accompanied by the uptake of protons. Therefore, nitrate uptake transporters (NRTs) may be involved in plant tolerance to proton toxicity. We investigated the root nitrate uptake response to proton stress in Arabidopsis and its association with proton tolerance using NRT-related mutants and pharmacological methods. Lack of NRT1.1 in knockout nrt1.1 mutants led to impaired proton tolerance in nitrate-sufficient growth medium, whereas no difference was seen between wild-type plants and NRT1.2-, NRT2.1-, NRT2.2-, and NRT2.4-null mutants. Another nrt1.1 point mutant, which is defective in nitrate uptake but has a normal nitrate-sensing function, also had impaired proton tolerance compared with the wild-type plant. Furthermore, proton stress induced NRT1.1-mediated nitrate uptake. These results indicate that NRT1.1-conferred proton tolerance depends on nitrate uptake activity. In addition, the rooting medium was alkalified by wild-type plants, but not by knockout nrt1.1 mutants, and in pH-buffered medium, there were no differences in proton tolerance between wild-type plants and knockout nrt1.1 mutants. We conclude that NRT1.1-mediated nitrate uptake plays a crucial role in plant proton tolerance by alkalifying the rhizosphere. © 2016 The Authors. New Phytologist © 2016 New Phytologist Trust.

  7. Can wolves help save Japan's mountain forests?

    USGS Publications Warehouse

    Barber-Meyer, Shannon

    2017-01-01

    Japan’s wolves were extinct by 1905. Today Japan's mountain forests are being killed by overabundant sika deer and wild boars. Since the early 1990s, the Japan Wolf Association has proposed wolf reintroduction to Japan to restore rural ecology and to return a culturally important animal. In this article I discuss whether the return of wolves could help save Japan's mountain forests.

  8. FBIS report. Science and technology: Japan, February 20, 1996

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1996-02-20

    ;Partial Contents: Energy (Japan: MHI Discovers Maritime Photo Plankton that Produces Ethanol from CO2, Japan: Tokyo Electric Power Co.`s PAFC Development); Telecommunications (Japan: Report on 1st Asian Telecommunications Industry Exchange, Japan: MPT Reports Test Evaluation Results for PHS); Defense Industries (Japan: Expert on Shipbuilding, Welding Technology, Japan: Komatsu R&D Chief on Dream of Ground Robots; Japan: Defense Simulator Series, Part 7: Torpedo Simulator).

  9. Providing Japanese health care information for international visitors: digital animation intervention.

    PubMed

    Nishikawa, Mariko; Yamanaka, Masaaki; Kiriya, Junko; Jimba, Masamine

    2018-05-21

    Over 24 million international visitors came to Japan in 2016 and the number is expected to increase. Visitors could be at a risk of illness or injury that may result in hospitalization in Japan. We assessed the effects of a four-minute digital animation titled Mari Info Japan on the level of anxiety experienced by international visitors to Japan. We conducted a non-randomized, controlled study at Narita International Airport outside Tokyo in December 2014. On the first day, we recruited international visitors for the intervention group at predetermined departure gates and, the following day, we sampled visitors for the control group at the same gates. We repeated this procedure twice over 4 days. The intervention group watched the digital animation and the control group read a standard travel guidebook in English. After receiving either intervention, they completed a questionnaire on their level of anxiety. The outcome was assessed using the Mari Meter-X, The State-Trait Anxiety Inventory Form Y (STAI-Y), and a face scale, before and immediately after the intervention. We analyzed data with Wilcoxon rank sum tests. We recruited 265 international visitors (134 in the intervention group, 131 in the control group), 241 (91%) of whom completed the questionnaire. Most of them had no previous Japanese health information before arrival in Japan. The level of anxiety about health services in Japan was significantly reduced in the intervention group (Mari Meter-X median: - 5 and 0, p < 0.001 and STAI-Y median: - 3 and 0, p < 0.001). The face scale analysis showed no significant difference. Watching a digital animation is more effective in reducing anxiety among international visitors to Japan compared with reading a standard brochure or guidebook. Such effective animations of health information should be more widely distributed to international visitors. UMIN-CTR (University Hospital Medical Information Network Center Clinical Trials Registry), UMIN000015023

  10. Yoga Therapy in Japan.

    PubMed

    Kimura, By Keishin

    2017-08-01

    This perspective piece gives an overview of the current situation of yoga therapy in Japan today. Traditional yoga in Japan suffered a serious setback in 1995 with a nerve gas terrorist attack on the Tokyo subway, which was carried out by a cult that recruited members through yoga classes. But with the increase in popularity with modern forms of yoga such as Iyengar yoga, Ashtanga yoga and hot yoga in the West, the general public in Japan today is forgetting its aversion to yoga and considers it to be something that can contribute to good health. In 2012, the Japan Yoga Therapy Society (JYTS) conducted a study on adverse events in yoga classes throughout Japan with the University of Kyushu School of Medicine, with support from the Ministry of Health, Labour and Welfare. This study indicated that more than half of people attending yoga classes have some form of chronic illness, with 42.3% receiving outpatient care. This survey was the beginning of growing interest from both the government and universities in yoga therapy. JYTS is beginning to make inroads into bringing yoga therapy into cancer and palliative care, senior citizen homes, alcohol and drug addiction rehabilitation, cardiovascular rehabilitation, and research on trauma and schizophrenia. While there are still limited opportunities for yoga therapists to work in mainstream healthcare services, there is growing interest among medical professionals in both physical and mental health. JYTS is beginning to make inroads into bringing yoga therapy into cancer and palliative care, senior citizen homes, alcohol and drug addiction rehabilitation, cardiovascular rehabilitation, and research on trauma and schizophrenia. While there are still limited opportunities for yoga therapists to work in mainstream healthcare services, there is growing interest among medical professionals in both physical and mental health. This perspective piece introduces some of the developments in yoga therapy research and practice in

  11. Yoga Therapy in Japan.

    PubMed

    Kimura, Keishin

    2017-11-01

    This perspective piece gives an overview of the current situation of yoga therapy in Japan today. Traditional yoga in Japan suffered a serious setback in 1995 with a nerve gas terrorist attack on the Tokyo subway, which was carried out by a cult that recruited members through yoga classes. But with the increase in popularity with modern forms of yoga such as Iyengar yoga, Ashtanga yoga and hot yoga in the West, the general public in Japan today is forgetting its aversion to yoga and considers it to be something that can contribute to good health. In 2012, the Japan Yoga Therapy Society (JYTS) conducted a study on adverse events in yoga classes throughout Japan with the University of Kyushu School of Medicine, with support from the Ministry of Health, Labour and Welfare. This study indicated that more than half of people attending yoga classes have some form of chronic illness, with 42.3% receiving outpatient care. This survey was the beginning of growing interest from both the government and universities in yoga therapy. JYTS is beginning to make inroads into bringing yoga therapy into cancer and palliative care, senior citizen homes, alcohol and drug addiction rehabilitation, cardiovascular rehabilitation, and research on trauma and schizophrenia. While there are still limited opportunities for yoga therapists to work in mainstream healthcare services, there is growing interest among medical professionals in both physical and mental health. JYTS is beginning to make inroads into bringing yoga therapy into cancer and palliative care, senior citizen homes, alcohol and drug addiction rehabilitation, cardiovascular rehabilitation, and research on trauma and schizophrenia. While there are still limited opportunities for yoga therapists to work in mainstream healthcare services, there is growing interest among medical professionals in both physical and mental health. This perspective piece introduces some of the developments in yoga therapy research and practice in

  12. TWELVE DOORS TO JAPAN.

    ERIC Educational Resources Information Center

    BEARDSLEY, RICHARD K.; HALL, JOHN WHITNEY

    THE TWELVE DOORS OF THIS COLLEGE-LEVEL TEXT ARE TWELVE CHAPTERS ON ASPECTS OF JAPAN AND JAPANESE CULTURE AS TREATED BY VARIOUS ACADEMIC DISCIPLINES. THE AUTHORS' PURPOSE IN CHOOSING THIS FORMAT WAS TO PRESENT INTRODUCTORY INFORMATION ABOUT JAPAN AND TO ACQUAINT STUDENTS WITH THE AIMS, MATERIALS, AND METHODS OF DISCIPLINES OTHER THAN THE ONE THEY…

  13. Helicobacter pylori infection in Japan

    PubMed Central

    Shiota, Seiji; Murakawi, Kazunari; Suzuki, Rumiko; Fujioka, Toshio; Yamaoka, Yoshio

    2013-01-01

    The prevalence of Helicobacter pylori infection is gradually decreasing in Japan. On the main island of Japan, nearly all H. pylori isolates possess cagA and vacA with strong virulence. However, less virulent H. pylori strains are frequently found in Okinawa where cases of gastric cancer are the lowest in Japan. Eradication therapy for peptic ulcer, idiopathic thrombocytopenic purpura, gastric mucosa-associated lymphoid tissue lymphoma and early gastric cancer after endoscopic resection has been approved by the Japanese national health insurance system. However, the Japanese Society for Helicobacter Research recently stated that all ‘H. pylori infection’ was considered as the indication for eradication irrespective of the background diseases. To eliminate H. pylori in Japan, the Japanese health insurance system should approve the eradication of all H. pylori infections. PMID:23265147

  14. Use and acquisition of nicotine replacement therapy products among underaged adolescents after deregulation of the sales.

    PubMed

    Rainio, Susanna U; Huhtala, Heini S A; Rimpelä, Arja H

    2010-08-01

    Limited information is available on the use and acquisition of nicotine replacement therapy (NRT) products in minors after deregulation of the sales. In Finland, deregulation releasing the NRT products for general sale took place in 2006. The sale is prohibited to those under the age of 18 years. We examine underaged adolescents' use, acquisition, and awareness of NRT products after the deregulation. Nationwide mailed survey of 12- to 18-year olds (N = 5,840, response rate 61%) was conducted in 2007. The main outcomes were ever use of NRT, acquisition of NRT products in different locations (retail outlet, family member, friend, health care personnel, and pharmacy), and awareness of NRT. Eighteen-year olds were analyzed as a comparison group as they were at legal age to buy the products. Among 14-year olds, 2% of boys and 2% of girls had used NRT. The corresponding figures for 16-year olds were 7% and 5%, respectively, and for 18-year olds 10% and 8%, respectively. Few 12-year olds had used NRT. Over a quarter of 12-year-old girls and 15% of boys did not know what NRT products were. Awareness increased with age. Of 12- to 16-year-old NRT users, 79% were daily smokers, 10% had smoked >50 but not daily, 10% had smoked <50, and 2% were never-smokers. The underaged NRT users acquired the products mainly not only from friends (42%) but also from retail outlets (13%). One year after deregulation, NRT use among minors is uncommon. Also misuse seems rare. NRT products are sold to minors from retail outlets despite sales ban. However, the underaged NRT users acquired the products mainly from friends.

  15. Addressing the evidence for FDA nicotine replacement therapy label changes: a policy statement of the Association for the Treatment of Tobacco use and Dependence and the Society for Research on Nicotine and Tobacco.

    PubMed

    Fucito, Lisa M; Bars, Matthew P; Forray, Ariadna; Rojewski, Alana M; Shiffman, Saul; Selby, Peter; West, Robert; Foulds, Jonathan; Toll, Benjamin A

    2014-07-01

    Cigarette smoking creates a substantial public health burden. Identifying new, effective smoking cessation interventions that optimize existing interventions and promoting effective use of approved medications is a priority. When used as directed, nicotine replacement therapy (NRT) aids smoking cessation, but there is opportunity for improving its effectiveness. Until recently, NRT use guidelines advised smokers to begin using NRT on their quit date, only to use 1 NRT formulation at a time, to refrain from using NRT while smoking, and to stop NRT within 3 months regardless of progress. The Food and Drug Administration (FDA) issued a recent announcement allowing for NRT labeling changes with applications from pharmaceutical companies for such changes, and we applaud this decision. Nevertheless, additional revisions are warranted by current research. There is robust evidence that combining a longer-acting form (e.g., patch) with a shorter-acting form (e.g., lozenge) is more effective than NRT monotherapy and is safe. Moreover, extant evidence suggests that NRT use prior to a quit attempt or for smoking reduction as part of a quit attempt is safe and as effective as starting NRT on quit date. Specifically, prequit nicotine patch increases quit rates and may engage additional recalcitrant smokers. Last, NRT use longer than 3 months is safe and may be beneficial for relapse prevention in some smokers. This report summarizes the FDA announcement, reviews the evidence for further revisions to current FDA NRT guidelines, and makes recommendations for over-the-counter (OTC) NRT labeling to allow for (1) combined use of faster-acting NRT medications with nicotine patch, (2) nicotine patch use prior to quit date or NRT for smoking reduction as part of a quit attempt, and (3) prolonged NRT for up to 6 months without healthcare provider consultation. © The Author 2014. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco. All

  16. Sleep, serotonin, and suicide in Japan.

    PubMed

    Kohyama, Jun

    2011-01-01

    This article reviews evidence supporting the hypothesis that suicide rates in Japan could be reduced by elevating serotonin levels via increasing the average duration of sleep. Seven major relevant findings were apparent in the literature: 1) Sleep loss is associated with suicide, but the direction of causality is equivocal. 2) Decreased serotonergic activity may be involved in suicidal behavior. 3) Sleep debt may decrease serotonergic activity. 4) The suicide rate in Japan has remained at a heightened level for the past 12 years. 5) The average sleep duration in Japan has decreased over the past 40 years. 6) The average sleep duration in Japan is among the lowest in the world. 7) The average sleep duration in Japan plateaued in 1995 and has been relatively stable since. From the research reviewed, two major problematic issues were apparent: 1) Most people in Japan receive inadequate sleep. 2) Individuals whose sleep is inadequate are unlikely to be sufficiently physically active to stimulate serotonergic systems to a desirable level. I propose that public health initiatives encouraging a longer duration of sleep may provide a relatively simple way of addressing the disturbing current trend in Japan. The combination of actigraph and brain serotonin level measurement could allow large population-based cohort studies to be designed, to elucidate the causal links between sleep duration, serotonin levels, and suicide rates.

  17. Psychology in Japan.

    PubMed

    Imada, Hiroshi; Tanaka-Matsumi, Junko

    2016-06-01

    The purpose of this article is to provide information about Japan and its psychology in advance of the 31st International Congress of Psychology (ICP), to be held in Yokohama, Japan, in 2016. The article begins with the introduction of the Japanese Psychological Association (JPA), the hosting organization of the ICP 2016, and the Japanese Union of Psychological Associations consisting of 51 associations/societies, of which the JPA is a member. This is followed by a brief description of a history of psychology of Japan, with emphasis on the variation in our approach to psychology in three different periods, that is, the pre- and post-Pacific War periods, and the post-1960 period. Next, the international contributions of Japanese psychology/psychologists are discussed from the point of view of their visibility. Education and training in psychology in Japanese universities is discussed with a final positive remark about the long-awaited enactment of the Accredited Psychologist Law in September, 2015. © 2016 International Union of Psychological Science.

  18. Is nicotine replacement therapy overvalued in smoking cessation? Analysis of smokers' and quitters' communication in social media.

    PubMed

    Kurko, Terhi; Linden, Kari; Kolstela, Maija; Pietilä, Kirsi; Airaksinen, Marja

    2015-12-01

    Internet discussion forums provide new, albeit less used data sources for exploring personal experiences of illness and treatment strategies. To gain an understanding of how discussion forum participants value nicotine replacement therapy (NRT) in smoking cessation (SC). Finnish national Internet-based discussion forum, STUMPPI, supporting SC and consisting of ten free discussion areas, each with a different focus. The analysis was based on STUMPPI forum participants' postings (n = 24 481) in five discussion areas during January 2007-January 2012. Inductive content analysis of the postings concerning NRT use or comparing NRT to other SC methods. Three major themes related to NRT in SC emerged from the discussions. These were as follows: (I) distrust and negative attitude towards NRT; (II) neutral acceptance of NRT as a useful SC method; and (III) trust on the crucial role of NRT and other SC medicines. The negative attitude was related to following perceptions: NRT use maintains tobacco dependence, fear of NRT dependence or experience of not gaining help from NRT use. NRT was perceived to be useful particularly in the initiation of SC attempts and in dealing with physiological dependence. The most highlighted factors of successful quitting were quitters' own psychological empowerment and peer support from the discussion community. The majority of STUMPPI forum participants had low or balanced expectations towards the role of NRT in SC. More research from the smokers' and quitters' perspective is needed to assess the real value of NRT compared to other methods in SC. © 2014 John Wiley & Sons Ltd.

  19. Guidelines for obstetrical practice in Japan: Japan Society of Obstetrics and Gynecology (JSOG) and Japan Association of Obstetricians and Gynecologists (JAOG) 2014 edition.

    PubMed

    Minakami, Hisanori; Maeda, Tsugio; Fujii, Tomoyuki; Hamada, Hiromi; Iitsuka, Yoshinori; Itakura, Atsuo; Itoh, Hiroaki; Iwashita, Mitsutoshi; Kanagawa, Takeshi; Kanai, Makoto; Kasuga, Yoshio; Kawabata, Masakiyo; Kobayashi, Kosuke; Kotani, Tomomi; Kudo, Yoshiki; Makino, Yasuo; Matsubara, Shigeki; Matsuda, Hideo; Miura, Kiyonori; Murakoshi, Takeshi; Murotsuki, Jun; Ohkuchi, Akihide; Ohno, Yasumasa; Ohshiba, Yoko; Satoh, Shoji; Sekizawa, Akihiko; Sugiura, Mayumi; Suzuki, Shunji; Takahashi, Tsuneo; Tsukahara, Yuki; Unno, Nobuya; Yoshikawa, Hiroyuki

    2014-06-01

    The 'Clinical Guidelines for Obstetrical Practice, 2011 edition' were revised and published as a 2014 edition (in Japanese) in April 2014 by the Japan Society of Obstetrics and Gynecology and the Japan Association of Obstetricians and Gynecologists. The aims of this publication include the determination of current standard care practices for pregnant women in Japan, the widespread use of standard care practices, the enhancement of safety in obstetrical practice, the reduction of burdens associated with medico-legal and medico-economical problems, and a better understanding between pregnant women and maternity-service providers. The number of Clinical Questions and Answers items increased from 87 in the 2011 edition to 104 in the 2014 edition. The Japanese 2014 version included a Discussion, a List of References, and some Tables and Figures following the Answers to the 104 Clinical Questions; these additional sections covered common problems and questions encountered in obstetrical practice, helping Japanese readers to achieve a comprehensive understanding. Each answer with a recommendation level of A, B or C was prepared based principally on 'evidence' or a consensus among Japanese obstetricians in situations where 'evidence' was weak or lacking. Answers with a recommendation level of A or B represent current standard care practices in Japan. All 104 Clinical Questions and Answers items, with the omission of the Discussion, List of References, and Tables and Figures, are presented herein to promote a better understanding among English readers of the current standard care practices for pregnant women in Japan. © 2014 The Authors. Journal of Obstetrics and Gynaecology Research © 2014 Japan Society of Obstetrics and Gynecology.

  20. Microsystems Research in Japan

    DTIC Science & Technology

    2003-09-01

    microsystems applications, like microfluidic systems, will require more than planar lithography -based fabrication processes. The committee was impressed by the...United States focused on exploiting silicon planar lithography as the core technology for microstructure fabrication, whereas Japan explored a wide...including LIGA and its extensions, micro-stereolithography, and e-beam lithography . The range of materials seen in Japan was broader than in the

  1. [History of pandemic influenza in Japan].

    PubMed

    Matsumoto, Keizo

    2010-09-01

    In Japan, influenza like epidemics were described many times since Heian era. However, Spanish flu as the modern medicine invaded Japan in 1918, thus almost infected 390,000 patients died with associated pneumonia. After the discovery of influenza virus in 1933, Japan experienced pandemic influenza--Asian flu(H2N2) in 1957. After about 10 years, Hong Kong flu (H3N2) came to Japan at 1968. However, we had many reliable antibiotics but had not any antiviral drug at the early time. After year 2000, we fortunately obtained reliable three antiviral drugs such as amantadine, oseltamivir and zanamivir. Moreover, very useful rapid test kits for influenza A and B viruses were developed and used in Japan. 2009 H1N1 influenza epidemic occured in Japan after the great epidemic in Mexico and North America but elderly patient was few. With together, host conditions regarding with high risk are changing. Lessons from past several pandemic influenza are those that many issues for changing high risk conditions, viral genetic changes, developing antiviral agents, developing new useful vaccins and determinating bacterial secondary pathogens are important.

  2. 75 FR 38119 - Polychloroprene Rubber From Japan

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-01

    ... Rubber From Japan AGENCY: United States International Trade Commission. ACTION: Institution of a five-year review concerning the antidumping duty finding on polychloroprene rubber from Japan. SUMMARY: The... on polychloroprene rubber from Japan would be likely to lead to continuation or recurrence of...

  3. Electronic manufacturing and packaging in Japan

    NASA Technical Reports Server (NTRS)

    Kelly, Michael J.; Boulton, William R. (Editor); Kukowski, John A.; Meieran, Eugene S.; Pecht, Michael; Peeples, John W.; Tummala, Rao R.

    1995-01-01

    This report summarizes the status of electronic manufacturing and packaging technology in Japan in comparison to that in the United States, and its impact on competition in electronic manufacturing in general. In addition to electronic manufacturing technologies, the report covers technology and manufacturing infrastructure, electronics manufacturing and assembly, quality assurance and reliability in the Japanese electronics industry, and successful product realization strategies. The panel found that Japan leads the United States in almost every electronics packaging technology. Japan clearly has achieved a strategic advantage in electronics production and process technologies. Panel members believe that Japanese competitors could be leading U.S. firms by as much as a decade in some electronics process technologies. Japan has established this marked competitive advantage in electronics as a consequence of developing low-cost, high-volume consumer products. Japan's infrastructure, and the remarkable cohesiveness of vision and purpose in government and industry, are key factors in the success of Japan's electronics industry. Although Japan will continue to dominate consumer electronics in the foreseeable future, opportunities exist for the United States and other industrial countries to capture an increasingly large part of the market. The JTEC panel has identified no insurmountable barriers that would prevent the United States from regaining a significant share of the consumer electronics market; in fact, there is ample evidence that the United States needs to aggressively pursue high-volume, low-cost electronic assembly, because it is a critical path leading to high-performance electronic systems.

  4. Electronics manufacturing and assembly in Japan

    NASA Technical Reports Server (NTRS)

    Kukowski, John A.; Boulton, William R.

    1995-01-01

    In the consumer electronics industry, precision processing technology is the basis for enhancing product functions and for minimizing components and end products. Throughout Japan, manufacturing technology is seen as critical to the production and assembly of advanced products. While its population has increased less than 30 percent over twenty-five years, Japan's gross national product has increase thirtyfold; this growth has resulted in large part from rapid replacement of manual operations with innovative, high-speed, large-scale, continuously running, complex machines that process a growing number of miniaturized components. The JTEC panel found that introduction of next-generation electronics products in Japan goes hand-in-hand with introduction of new and improved production equipment. In the panel's judgment, Japan's advanced process technologies and equipment development and its highly automated factories are crucial elements of its domination of the consumer electronics marketplace - and Japan's expertise in manufacturing consumer electronics products gives it potentially unapproachable process expertise in all electronics markets.

  5. Japan’s Role in the New Era

    DTIC Science & Technology

    1992-04-15

    JAPAN’S ROLE IN THE NEW ERA BY .1 Colonel Yasuhiro Naomi ELECTE .F Japan Ground Self Defense Force ,4aY 1.4 19,92 A DISTRIBUTION STATEMENT A: Approved...Colonel Yasuhiro Naomi D.ti ibltof Japan Ground Self Defense Force ,v’ilti~ity Cod - A~a~i ardj r Colonel Donald W. Boose, Jr...Pennsylvania 17013 ABSTRACT AUTHOR: Colonel Yasuhiro Naomi, Japan Ground Self -Defense Force TITLE: Japan’s Role in the New Era FORMAT: Individual Study

  6. Explaining Meiji Japans Top Down Revolution

    DTIC Science & Technology

    2017-12-01

    enabled Japan to become a great power also provides insights into how Japan became what it is today—an economically strong but militarily weak country...top- down nature of the Japanese revolution allowed for effective decision-making that centralized domestic politics and boosted economic ...other road focuses on changes made to compete with the West in the economic and military realm. Since Meiji Japan began in reaction to hostile Western

  7. Tobacco Industry Research on Nicotine Replacement Therapy: "If Anyone Is Going to Take Away Our Business It Should Be Us".

    PubMed

    Apollonio, Dorie; Glantz, Stanton A

    2017-10-01

    Nicotine replacement therapy (NRT) is recommended for tobacco cessation on the basis of pharmaceutical industry research showing its effectiveness when combined with counseling. The tobacco industry opposed NRT when it first appeared in the 1980s but by 2016 was marketing its own NRT products. We used internal tobacco industry documents dated 1960 through 2010 to identify the industry's perceptions of NRT. As early as the 1950s, tobacco companies developed nonsmoked nicotine replacements for cigarettes, but they stopped out of concern that marketing such products would trigger Food and Drug Administration regulation of cigarettes. In the 1990s, after pharmaceutical companies began selling prescription NRT, tobacco companies found that many smokers used NRT to supplement smoking rather than to quit. In 2009, once the Food and Drug Administration began regulating tobacco, tobacco companies restarted their plans to capture the nicotine market. Although the tobacco industry initially viewed NRT as a threat, it found that smokers often combined NRT with smoking rather than using it as a replacement and began marketing their own NRT products.

  8. Contraception in Japan: Current trends.

    PubMed

    Yoshida, Honami; Sakamoto, Haruka; Leslie, Asuka; Takahashi, Osamu; Tsuboi, Satoshi; Kitamura, Kunio

    2016-06-01

    High proportion of Japanese uses condoms; lower proportion uses oral contraceptive pills (OCPs). We examined the longitudinal patterns for contraceptive usage in Japan and evaluated differences before and after OCP government approval. We accessed nationally representative survey data for women aged 16-49years from 1950 to 2014. Usage of condoms and OCP was 83.4% and 3.0%, respectively in 2014. OCP use before (1.21%) and after (1.97%) government approval did not differ significantly (p=.58). The prevalence of OCP usage remains low in Japan. A wide gap in use between Japan and other developed countries exists. Through a wide gap in OCP use between Japan and other countries, we revealed how choices of contraceptive methods and their benefits could be openly available for women of reproductive age, and how health care professionals disseminate appropriate knowledge about contraception for women in need. Copyright © 2016 Elsevier Inc. All rights reserved.

  9. Recent trends for drug lag in clinical development of oncology drugs in Japan: does the oncology drug lag still exist in Japan?

    PubMed

    Maeda, Hideki; Kurokawa, Tatsuo

    2015-12-01

    This study exhaustively and historically investigated the status of drug lag for oncology drugs approved in Japan. We comprehensively investigated oncology drugs approved in Japan between April 2001 and July 2014, using publicly available information. We also examined changes in the status of drug lag between Japan and the United States, as well as factors influencing drug lag. This study included 120 applications for approval of oncology drugs in Japan. The median difference over a 13-year period in the approval date between the United States and Japan was 875 days (29.2 months). This figure peaked in 2002, and showed a tendency to decline gradually each year thereafter. In 2014, the median approval lag was 281 days (9.4 months). Multiple regression analysis identified the following potential factors that reduce drug lag: "Japan's participation in global clinical trials"; "bridging strategies"; "designation of priority review in Japan"; and "molecularly targeted drugs". From 2001 to 2014, molecularly targeted drugs emerged as the predominant oncology drug, and the method of development has changed from full development in Japan or bridging strategy to global simultaneous development by Japan's taking part in global clinical trials. In line with these changes, the drug lag between the United States and Japan has significantly reduced to less than 1 year.

  10. Advanced composites in Japan

    NASA Technical Reports Server (NTRS)

    Diefendorf, R. Judd; Hillig, William G.; Grisaffe, Salvatore J.; Pipes, R. Byron; Perepezko, John H.; Sheehan, James E.

    1994-01-01

    The JTEC Panel on Advanced Composites surveyed the status and future directions of Japanese high-performance ceramic and carbon fibers and their composites in metal, intermetallic, ceramic, and carbon matrices. Because of a strong carbon and fiber industry, Japan is the leader in carbon fiber technology. Japan has initiated an oxidation-resistant carbon/carbon composite program. With its outstanding technical base in carbon technology, Japan should be able to match present technology in the U.S. and introduce lower-cost manufacturing methods. However, the panel did not see any innovative approaches to oxidation protection. Ceramic and especially intermetallic matrix composites were not yet receiving much attention at the time of the panel's visit. There was a high level of monolithic ceramic research and development activity. High temperature monolithic intermetallic research was just starting, but notable products in titanium aluminides had already appeared. Matrixless ceramic composites was one novel approach noted. Technologies for high temperature composites fabrication existed, but large numbers of panels or parts had not been produced. The Japanese have selected aerospace as an important future industry. Because materials are an enabling technology for a strong aerospace industry, Japan initiated an ambitious long-term program to develop high temperature composites. Although just starting, its progress should be closely monitored in the U.S.

  11. Will Japan Become a Military Superpower?

    DTIC Science & Technology

    1993-04-15

    SOURCE OF FUNDING NUMBERS PROGRAM PROJECT TASK WORK ý;NiT ELEMENT NO. NO. NO. CCESSiON NO 11. TITLE (Include Security Ciassification) Will Japan Become a... competition , Japan can no longer continue with status quo. Security relationships within the Asia-Pacific region are changing. The end of the Cold War...of the work on the aircraft while Mitsubishi would pick up the remaining 60 percent. This aircraft will use leading-edge technology. Japan wants to

  12. Urologic cancer in Japan: role of Japan at the frontier of issues in Asia.

    PubMed

    Akaza, Hideyuki

    2016-01-01

    The characteristics of urological cancer in Japan can be summarized in the following points. (i) As the onset of this type of cancer is typically seen in elderly patients, it is becoming a major social issue in Japan that has already become an aging society. (ii) Many diverse treatment methods are available and a response is required that prioritizes quality of life. (iii) Although vigorous research and development efforts into new drugs are being carried out on a global level, resulting in beneficial medical agents becoming more readily available, unless concepts relating to cost vs. effectiveness are further developed and there is a real risk that medical systems and structures in their current form will become unsustainable. (iv) Although at the current point there are no original large-scale clinical trials being conducted in Asia, Japan has a wealth of experience of participating in many international joint clinical trials and it is therefore an urgent and pressing challenge to organize joint clinical trials in Asia and amass a body of knowledge that is unique to Asia. In view of this current situation and given Japan's position at the frontier of issues, it is important for Japan to take the initiative in Asia in cooperating with other Asian nations in efforts to resolve and overcome various challenges. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  13. The US Occupation and Japan's New Democracy

    ERIC Educational Resources Information Center

    Kumano, Ruriko

    2007-01-01

    During the US Occupation of Japan (1945-1952), a victorious America attempted to reform Japanese education by replacing Japan's tradition system of values with one that promoted American democratic values. The United States had considered the source of Japan's militarism to lie in the selfless loyalty and love of country that many older Japanese…

  14. History Textbook Controversies in Japan. ERIC Digest.

    ERIC Educational Resources Information Center

    Masalski, Kathleen Woods

    Currently, there is a controversy in Japan about textbook treatments of Japanese military actions during World War II. This digest examines: (1) the importance of history textbooks in schools in Japan and the United States; (2) the context of history textbook controversies in Japan; (3) the current issues and contending positions in the Japanese…

  15. Legislative Basis of Pedagogical Education in Japan

    ERIC Educational Resources Information Center

    Kuchai, Tetiana

    2014-01-01

    Legal framework policy of Japan in the field of education has been analyzed. The problem of influence of legislative materials on the development of education in Japan, its legislative support has been considered. It has been defined that directive materials affect the development of education system in Japan. Legislation policy of the country is…

  16. A Critical Evaluation of Nicotine Replacement Therapy for Teenage Smokers.

    ERIC Educational Resources Information Center

    Patten, Christi A.

    2000-01-01

    Evaluates the appropriateness and feasibility of nicotine replacement therapy (NRT) in teenage smokers. Available forms of NRT, theoretical rationale and efficacy of NRT, ethical considerations, and the feasibility of NRT in teenage smokers are addressed. Several characteristics similar to adult nicotine dependent smokers have been found in teen…

  17. Ehrlichia chaffeensis Infection of Sika Deer, Japan

    PubMed Central

    Kawahara, Makoto; Tajima, Tomoko; Torii, Harumi; Yabutani, Mitsutaka; Ishii, Joji; Harasawa, Makiko; Isogai, Emiko

    2009-01-01

    To determine whether Ehrlichia chaffeensis exists in Japan, we used PCR to examine blood from sika deer in Nara, Japan. Of 117 deer, 36 (31%) were infected with E. chaffeensis. The E. chaffeensis 16S rRNA base and GroEL amino acid sequences from Japan were most closely related to those of E. chaffeensis Arkansas. PMID:19961683

  18. Use of Neural Response Telemetry for Pediatric Cochlear Implants: Current Practice.

    PubMed

    Almosnino, Galit; Anne, Samantha; Schwartz, Seth R

    2018-06-01

    Evaluate usage trends of neural response telemetry (NRT) in cochlear implant centers across the nation and assess reported benefits of intraoperative NRT for pediatric cochlear implant recipients. Survey. All US cochlear implant centers (n = 110). A 15-question multiple-choice survey was distributed electronically to all centers. The survey captured demographic information of all centers, practice patterns surrounding the use of NRT, and the extent to which intraoperative NRT is of benefit. Thirty-two invited participants (29%) completed the survey. A majority of participants reported practicing in an academic center (66%), followed by a hospital setting (19%) and private practice (16%). Seventy-two percent of survey participants reported using NRT for pediatric cochlear implant recipients. Sixty-three percent felt it improved the ability to program at initial activation, and 50% of participants felt that NRT improves satisfaction at initial activation. This study suggests that a majority of surgeons use intraoperative NRT for pediatric cochlear implantation as an additional measure to ensure appropriate electrode placement and improve device activation. Larger studies are needed to better establish the relationship between intraoperative NRT and postoperative outcomes and justify the additional costs associated with intraoperative NRT.

  19. Combination nicotine replacement therapy: strategies for initiation and tapering.

    PubMed

    Hsia, Stephanie L; Myers, Mark G; Chen, Timothy C

    2017-04-01

    Several studies and meta-analyses have demonstrated the efficacy of combination nicotine replacement therapy (NRT) for patients who wish to quit smoking. However, there is limited guidance with respect to initiation and tapering of combination NRT. We attempt to review the evidence and rationale behind combination NRT, present the dosing used in combination NRT studies, and propose a step-down approach for tapering of combination NRT with integration of behavioral strategies. Copyright © 2017. Published by Elsevier Inc.

  20. The Japan Medical Association's disaster preparedness: lessons from the Great East Japan Earthquake and Tsunami.

    PubMed

    Ishii, Masami; Nagata, Takashi

    2013-10-01

    A complex disaster, the Great East Japan Earthquake of March 11, 2011, consisted of a large-scale earthquake, tsunami, and nuclear accident, resulting in more than 15 000 fatalities, injuries, and missing persons and damage over a 500-km area. The entire Japanese public was profoundly affected by "3/11." The risk of radiation exposure initially delayed the medical response, prolonging the recovery efforts. Japan's representative medical organization, the Japan Medical Association (JMA), began dispatching Japan Medical Association Teams (JMATs) to affected areas beginning March 15, 2011. About 1400 JMATs comprising nearly 5500 health workers were launched. The JMA coordinated JMAT operations and cooperated in conducting postmortem examination, transporting large quantities of medical supplies, and establishing a multiorganizational council to provide health assistance to disaster survivors. Importantly, these response efforts contributed to the complete recovery of the health care system in affected areas within 3 months, and by July 15, 2011, JMATs were withdrawn. Subsequently, JMATs II have been providing long-term continuing medical support to disaster-affected areas. However, Japan is at great risk for future natural disasters because of its Pacific Rim location. Also, its rapidly aging population, uneven distribution of and shortage of medical resources in regional communities, and an overburdened public health insurance system highlight the need for a highly prepared and effective disaster response system.

  1. Space robotics in Japan

    NASA Technical Reports Server (NTRS)

    Whittaker, William; Lowrie, James W.; Mccain, Harry; Bejczy, Antal; Sheridan, Tom; Kanade, Takeo; Allen, Peter

    1994-01-01

    Japan has been one of the most successful countries in the world in the realm of terrestrial robot applications. The panel found that Japan has in place a broad base of robotics research and development, ranging from components to working systems for manufacturing, construction, and human service industries. From this base, Japan looks to the use of robotics in space applications and has funded work in space robotics since the mid-1980's. The Japanese are focusing on a clear image of what they hope to achieve through three objectives for the 1990's: developing long-reach manipulation for tending experiments on Space Station Freedom, capturing satellites using a free-flying manipulator, and surveying part of the moon with a mobile robot. This focus and a sound robotics infrastructure is enabling the young Japanese space program to develop relevant systems for extraterrestrial robotics applications.

  2. Monitoring and tracking the trans-Pacific transport of aerosols using multi-satellite aerosol optical depth composites

    NASA Astrophysics Data System (ADS)

    Naeger, Aaron R.; Gupta, Pawan; Zavodsky, Bradley T.; McGrath, Kevin M.

    2016-06-01

    The primary goal of this study was to generate a near-real time (NRT) aerosol optical depth (AOD) product capable of providing a comprehensive understanding of the aerosol spatial distribution over the Pacific Ocean, in order to better monitor and track the trans-Pacific transport of aerosols. Therefore, we developed a NRT product that takes advantage of observations from both low-earth orbiting and geostationary satellites. In particular, we utilize AOD products from the Moderate Resolution Imaging Spectroradiometer (MODIS) and Suomi National Polar-orbiting Partnership (NPP) Visible Infrared Imaging Radiometer Suite (VIIRS) satellites. Then, we combine these AOD products with our own retrieval algorithms developed for the NOAA Geostationary Operational Environmental Satellite (GOES-15) and Japan Meteorological Agency (JMA) Multi-functional Transport Satellite (MTSAT-2) to generate a NRT daily AOD composite product. We present examples of the daily AOD composite product for a case study of trans-Pacific transport of Asian pollution and dust aerosols in mid-March 2014. Overall, the new product successfully tracks this aerosol plume during its trans-Pacific transport to the west coast of North America as the frequent geostationary observations lead to a greater coverage of cloud-free AOD retrievals equatorward of about 35° N, while the polar-orbiting satellites provide a greater coverage of AOD poleward of 35° N. However, we note several areas across the domain of interest from Asia to North America where the GOES-15 and MTSAT-2 retrieval algorithms can introduce significant uncertainties into the new product.

  3. Understanding and modulating the high-energy properties of noble-gas hydrides from their long-bonding: an NBO/NRT investigation on HNgCO+/CS+/OSi+ and HNgCN/NC (Ng = He, Ar, Kr, Xe, Rn) molecules.

    PubMed

    Zhang, Guiqiu; Song, Junjie; Fu, Lei; Tang, Kongshuang; Su, Yue; Chen, Dezhan

    2018-04-18

    The noble-gas hydrides, HNgX (X is an electronegative atom or fragment), represent potential high-energy materials because their two-body decomposition process, HNgX → Ng + HX, is strongly exoergic. Our previous studies have shown that each member of the HNgX (X = halogen atom or CN/NC fragment) molecules is composed of three leading resonance structures: two ω-bonding structures (H-Ng+ :X- and H:- Ng+-X) and one long-bonding structure (H∧X). The last one paints a novel [small sigma, Greek, circumflex]-type long-bonding picture. The present study focuses on the relationship between this novel bonding motif and the unusual energetic properties. We chose HNgCO+/CS+/OSi+/CN/NC, with the formula HNgAB (Ng = He, Ar, Kr, Xe, Rn; AB = CO+/CS+/OSi+/CN/NC) as the research system. We first investigated the bonding of HNgCO+ and its analogous HNgCS+/OSi+ species using NBO/NRT methods, and quantitatively compared the bonding with that in HNgCN/NC molecules. NBO/NRT results showed that each of the HNgCO+/CS+/OSi+ molecules could be better represented as a resonance hybrid of ω-bonding and long-bonding structures, but the long-bonding is much weaker than that in HNgCN/NC molecules. Furthermore, we introduced the long-bonding concept into the rationalization of the high-energy properties, and found a good correlation between the highly exothermic two-body dissociation channel and the long-bond order, bH-A. We also found that the long-bond order is highly tunable for these noble-gas hydrides due to its dependence on the nature of the electronegative AB fragments or the central noble-gas atoms, Ng. On the basis of these results, we could optimize the energetic properties by changing the long-bonding motif of our studied molecules. Overall, this study shows that the long-bonding model provides an easy way to rationalize and modulate the unusual energy properties of noble-gas hydrides, and that it is helpful to predict some noble-gas hydrides as potential energetic materials.

  4. [Abortion in Japan].

    PubMed

    Yamamoto, K; Yamamoto, Y; Hayase, T

    1993-01-01

    In Japan, the artificial abortion is a penal offence; only in the presence of certain conditions it is authorized under the provision of the Eugenic Protection Law which was promulgated in 1948. According to the law, the artificial abortion is restricted to the period, in which the fetus is not viable outside of the uterus. This period is prescribed by notification from the Ministry of Public Welfare; up to now it has been shortened twice (1976, 1991). Due to the introduction of economic reasons in the list of conditions and the simplification of the procedure the artificial abortion in Japan was virtually liberalized. Prosecution for illegal abortion is very rare in recent years. The number of reported artificial abortions decreases; in the about last 30 years it reduced by half. However, the increase in the number of abortions in women younger than 20 years of age is a problem. The abortion in teenagers is late compared with that in other age groups. Although the number of neonaticides does not seem to increase, the increase in the number of abortions in teenagers remains a serious problem in Japan.

  5. Japanese-U.S. Economic Relations. Japan Digest.

    ERIC Educational Resources Information Center

    Ellington, Lucien

    World War II was the last time when overall U.S.-Japan relations, and the economic relationship in particular, were as bad as appears to be the case in the 1990s. The United States and Japan are, respectively, the two largest economies in the world. The Japanese have the second leading market for U.S. products trailing only Canada. Japan buys more…

  6. Higher Education Studies in Japan

    ERIC Educational Resources Information Center

    Kaneko, Motohisa

    2010-01-01

    The rapid development of higher education in the postwar period has given rise to various problems, and higher education studies in Japan have developed in response to them. What have been the major issues, and how did academic research respond to them, in postwar Japan? This article delineates an outline of higher education studies in general,…

  7. Disaster relief activities of the Japan self-defense force following the Great East Japan Earthquake.

    PubMed

    Nishiyama, Yasumasa

    2014-06-01

    Cooperation between civilian and military forces, including the Japan Self-Defense Force (JSDF), enabled wide-ranging disaster relief after the Great East Japan Earthquake. Nevertheless, many preventable fatalities occurred, particularly related to an inability to treat chronic disease, indicating the need to plan for the provision of long-term medical aid after natural disasters in stricken areas and evacuation shelters. To assist in this effort, this report (1) provides an overview of the consequences of the medical response to the Great East Japan Earthquake, the largest natural disaster ever to hit Japan, focusing on the role and actions of the JSDF; (2) discusses the lessons learned regarding the provision of medical aid and management by the JSDF after this disaster, looking at the special challenges of meeting the needs of a rapidly aging population in a disaster situation; and (3) provides recommendations for the development of strategies for the long-term medical aid and support after natural disasters, especially with regard to the demographics of the Japanese population.

  8. Neurosurgeons in Japan Are Exclusively Brain Surgeons.

    PubMed

    Asamoto, Shunji

    2017-03-01

    In Japan, neurosurgeons have traditionally mainly treated brain diseases, with most cases involving the spine and spinal diseases historically being treated by orthopedists. Nowadays, spinal surgery is 1 of the many subspecialties in the neurosurgical field in Japan. Most patients with neurological deficits or suspected neurological diseases see board-certified neurosurgeons directly in Japan, not through referrals from family physicians or specialists in other fields. Problems originating in the spine and spinal cord have been overlooked or misdiagnosed in these situations. Neurosurgeons in Japan must rethink the educational program to include advanced trauma life support and spinal surgery. Copyright © 2016. Published by Elsevier Inc.

  9. Seasonality in sales of nicotine replacement therapies: patterns and implications for tobacco control.

    PubMed

    Chandra, Siddharth; Gitchell, Joseph G; Shiffman, Saul

    2011-05-01

    Over the counter, nicotine replacement therapies (NRTs) are the most widely used smoking cessation treatment. This study sheds light on the seasonality of sales of NRT. A seasonal adjustment algorithm was applied to data on the sales of NRT products for 50 metro markets in the United States to test for and characterize seasonality in NRT sales. Granger's test was applied to the data to test whether changes in NRT sales systematically predicted changes in cigarette sales 1 month later. The results show (a) that sales of NRT products are seasonal, (b) that the seasonality pattern is the opposite of the seasonality pattern for cigarette sales, (c) that seasonally higher NRT sales in a given month tend to be followed by seasonally lower cigarette sales in the following month, and (d) that seasonally high months for NRT sales (January to March) correspond to seasonally low months for cigarette sales. NRT sales show a strong seasonality pattern that is the opposite of the seasonality pattern for cigarette sales. These patterns are indicative of seasonal variations in quitting behavior.

  10. Effect of deregulation on the prices of nicotine replacement therapy products in Finland.

    PubMed

    Aalto-Setälä, Ville; Alaranta, Antti

    2008-05-01

    The sales of nicotine replacement therapy (NRT) products were deregulated in Finland in February 2006. Previously all medications were sold only in pharmacies, and retail mark-ups and prices were fixed; following deregulation pricing of NRT products has been free. Further more, grocery shops, petrol stations and kiosks are now licensed to sell NRT products. The objective of this study is to evaluate the impact of deregulation on prices of NRT products. We utilized price data on NRT products (n=2106) from pharmacies, grocery shops, kiosks and petrol stations. Market prices are compared with former regulated prices, as are the prices at different types of outlets. We examined the relationship between competition and prices by regression analysis. The average price of NRT products decreased 15% after deregulation. About half of the price decrease was due to exemption of NRT products from the pharmacy fee as part of deregulation, and the other half to increased competition. The least expensive NRT products are obtainable in hypermarkets; however, pharmacies have the largest variety. Deregulation of NRT products in Finland was successful in that the prices of these products have decreased and their availability increased. Based on international experience, however, it is not clear whether these decreased prices and increased availabilities have increased smoking cessation.

  11. Patient-Centered Research Abstracts

    PubMed Central

    Thorndike, AN; Biener, L; Rigotti, NA

    2000-01-01

    PURPOSE Nicotine replacement therapy (NRT) sales switched from prescription to over-the-counter (OTC) status in April 1996. The change was expected to benefit public health by increasing smokers' access to NRT, and industry data show a doubling of NRT sales since the switch. We used a population-based sample to assess whether OTC availability increased smokers' rates of 1) NRT use, 2) quit attempts, and 3) cessation. METHODS We analyzed data from the Massachusetts Tobacco Surveys, telephone surveys of a probability sample of Massachusetts (MA) residents (response rates 68%–78%). We compared responses from past-year smokers in 1993 (pre-OTC; N = 1784) to those from 1997–99 (post-OTC; N = 1240), using multiple logistic regression. We also compared the demographic characteristics of NRT users before and after the OTC switch among smokers who had made a quit attempt in the past year. RESULTS There was no significant change over time in the proportion of respondents using NRT at a quit attempt in the past year (20.1% pre-OTC vs. 19.9% post-OTC) and no significant change in the proportion of smokers who made a quit attempt or who quit smoking. Half of smokers who used NRT post-OTC used it to "delay or cut down" their smoking but not to make a quit attempt. Fewer non-whites used NRT post-OTC (3.3%) compared to pre-OTC (20.7%) (adjusted p = .002), but the proportion of whites using NRT did not change (20.6% pre-OTC to 21.9% post-OTC). A higher proportion of 18–30 year-olds and a lower proportion openface>45 year-olds used NRT post-OTC compared to pre-OTC (adjusted p = .0004). CONCLUSION We find no evidence that the OTC switch was associated with increased NRT use, quit attempts, or cessation rates among MA smokers, and one explanation may be that smokers purchase OTC NRT for reasons other than cessation. Since the switch, access to NRT appears to have increased for young adults but decreased for older and minority smokers. Even though NRT is now sold OTC, it remains

  12. Japan: Tsunami

    Atmospheric Science Data Center

    2013-04-16

    ... tsunami triggered by the March 11, 2011, magnitude 8.9 earthquake centered off Japan's northeastern coast about 130 kilometers (82 ... inland from the eastern shoreline is visible in the post-earthquake image. The white sand beaches visible in the pre-earthquake view are ...

  13. Universal varicella vaccine immunization in Japan.

    PubMed

    Yoshikawa, Tetsushi; Kawamura, Yoshiki; Ohashi, Masahiro

    2016-04-07

    In 1974, Japanese scientists developed a live attenuated varicella vaccine based on the Oka strain. The efficacy of the vaccine for the prevention of varicella has been primarily demonstrated in studies conducted in the United States following the adoption of universal immunization using the Oka strain varicella vaccine in 1996. Although the vaccine was developed by Japanese scientists, until recently, the vaccine has been administered on a voluntary basis in Japan resulting in a vaccine coverage rate of approximately 40%. Therefore, Japan initiated universal immunization using the Oka strain varicella vaccine in November 2014. Given the transition from voluntary to universal immunization in Japan, it will also be important to monitor the epidemiology of varicella and herpes zoster. The efficacy and safety of co-administration of the varicella vaccine and measles, mumps, and rubella vaccine have been demonstrated in many countries; however, there was no data from Japan. In order to adopt the practice of universal immunization using the Oka strain varicella vaccine in Japan, data demonstrating the efficacy and safety of co-administration of varicella vaccine and measles and rubella (MR) vaccine were required. Additionally, we needed to elucidate the appropriate time interval between the first and second administrations of the vaccine. It is also important to differentiate between wild type and Oka vaccine type strains in herpes zoster patient with past history of varicella vaccine. Thus, there are many factors to consider regarding the adoption of universal immunization in Japan to control varicella zoster virus (VZV) infections. Copyright © 2016 Elsevier Ltd. All rights reserved.

  14. Psychohistorical Hypotheses on Japan's History of Hostility Towards China.

    PubMed

    Wang, Bo; Rudmin, Floyd

    2016-01-01

    The accelerating tensions and military posturing between Japan and China have created a serious crisis with a danger of a catastrophic war. The purpose of this paper is to summarize the events of the current crisis, and to put it in the context of Japan's long history of hostility to China and repeated attempts at conquest. The historical record shows that Japan has attacked China at least seven times, even though China has never attacked Japan. The irrationality of Japan's behavior is demonstrated by the repetition of this hostile behavior despite the enormous human and economic costs that Japan has suffered because of it. The irrationality of Japan's militarism suggests that psychological explanations may be required to understand this phenomenon. Several hypotheses are proposed, including 1) projected paranoid aggression, 2) collective Zeigarnik compulsion, 3) perceived weakness exciting aggression, 4) national inferiority feelings, 5) cultural narcissism, and 6) Oedipal-like hatred of a parent culture.

  15. From sword to chrysanthemum: Japan's culture of anti-miltarism

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Berger, T.U.

    The end of the Cold War and the phenomenal increase in Japan's economic and technological power put Japan today in the position to become, if it chooses, a military as well as economic superpower. The diminution of the Soviet threat and the increasing US preoccupation with domestic problems give Japan a latitude for independent action it has not had since the end of World War II. At the same time the US-Japanese security alliance, which has enabled Japan to adopt a minimalist approach to defense and national security, is being weakened by ideologically charged trade and other economic frictions andmore » a growing American perception of Japan as a threat to its interests. Moreover, in the long run Japan faces the prospect of having to deal with other rising regional powers, most notably the People's Republic of China. This changing international security environment thus raises question whether Japan, having become an economic rival of the United States, may not in the future become a military competitor as well; whether, after having adopted a pacifist stance for half a century, Japan may choose to unsheathe its sword once again.« less

  16. U.S.-Japan Quake Prediction Research

    NASA Astrophysics Data System (ADS)

    Kisslinger, Carl; Mikumo, Takeshi; Kanamori, Hiroo

    For the seventh time since 1964, a seminar on earthquake prediction has been convened under the U.S.-Japan Cooperation in Science Program. The purpose of the seminar was to provide an opportunity for researchers from the two countries to share recent progress and future plans in the continuing effort to develop the scientific basis for predicting earthquakes and practical means for implementing prediction technology as it emerges. Thirty-six contributors, 15 from Japan and 21 from the U.S., met in Morro Bay, Calif.September 12-14. The following day they traveled to nearby sections of the San Andreas fault, including the site of the Parkfield prediction experiment. The conveners of the seminar were Hiroo Kanamori, Seismological Laboratory, California Institute of Technology (Caltech), for the U.S., and Takeshi Mikumo, Disaster Prevention Research Institute, Kyoto University, for Japan . Funding for the participants came from the U.S. National Science Foundation and the Japan Society forthe Promotion of Science, supplemented by other agencies in both countries.

  17. Japan-U.S. Relations: Issues for Congress

    DTIC Science & Technology

    2008-05-23

    fields in an area of the East China Sea that both countries claim as their territory. Hu also announced that China would lease two giant pandas to Japan...to replace a recently deceased panda at a Tokyo zoo. Days later, after China was struck by a devastating earthquake, Japan immediately offered...other shipments of U.S. beef from Japan. In May 2007, the World Organization for Animal Health (OIE) announced that the United States was a “controlled

  18. The impact of advertising on nicotine replacement therapy demand.

    PubMed

    Tauras, John A; Chaloupka, Frank J; Emery, Sherry

    2005-05-01

    While much is known about the economic determinants of tobacco use, very little is known about the economic determinants of nicotine replacement therapy (NRT) use. This paper is the first econometric study to examine the impact of advertising on NRT demand. Pooled cross-sectional time-series scanner-based data for 50 major metropolitan markets in the USA covering the period between the second quarter of 1996 and the second quarter of 2002 are used in the analysis. Fixed-effects modeling is employed to estimate the NRT demand equation. The estimates indicate that increased advertising of Nicoderm CQ transdermal patches and Nicotrol transdermal patches increases per-capita sales of established Nicoderm CQ and Nicotrol products, respectively. However, increased advertising of Nicorette polacrilex (gum) was found not to significantly increase sales of established Nicorette products. Moreover, decreases in the price of NRT and increases in the price of cigarettes were found to increase per-capita sales of NRT products. Given the documented efficacy of NRT, measures to increase peoples' awareness of NRT products through advertising, measures to decrease the price of NRT, and measures to increase the price of cigarettes would be effective means to increase the use of NRT, likely leading to decreased cigarette smoking and reductions in the future public health burden caused by tobacco use.

  19. Beliefs of stop smoking practitioners in United Kingdom on the use of nicotine replacement therapy for smoking reduction.

    PubMed

    Beard, Emma; McDermott, Máirtín; McEwen, Andy; West, Robert

    2012-06-01

    This paper aimed to assess the current beliefs of stop smoking practitioners and managers about using nicotine replacement therapy (NRT) for smoking reduction (SR) and the factors related to these beliefs. An online survey was conducted of practitioners and managers working in the 152 English stop smoking services (SSSs). Questions were asked about their beliefs concerning the safety of using NRT for SR. Sixteen percent and 30% of the sample, respectively, believed that NRT use for a year or more and the concurrent use of NRT and cigarettes was harmful to health. The most commonly reported potential harms of the long-term use of NRT and the concurrent use of NRT and cigarettes were addiction, overdose and mouth cancer. Seventeen percent of the sample also believed that the use of NRT for SR could hinder smoking cessation. Reports differed as a function of the managers' relationship with their commissioner and influence on the commissioning process, while among practitioners as a function of the number of months worked, gender, frequency of update training and whether they advised reduction as a treatment option. A significant minority of stop smoking practitioners and stop smoking managers believe that NRT use for SR can be harmful to health and undermine smoking cessation. These beliefs should be addressed, especially if the use of NRT in these ways is provided as a route to quitting in SSSs.

  20. Teaching about Japan in Secondary Schools.

    ERIC Educational Resources Information Center

    Richardson, Helen W.

    1981-01-01

    Suggests that a good starting point for social studies curriculum units on Japan at the secondary school level is an analysis of the interrelationships between Japan and the United States. Information is presented on population figures, industrialization, standard of living indicators, consumer price indexes, and crude birth and death rates for…

  1. AERIAL MEASURING SYSTEM IN JAPAN

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lyons, Craig; Colton, David

    2012-01-01

    The U.S. Department of Energy National Nuclear Security Agency’s Aerial Measuring System deployed personnel and equipment to partner with the U.S. Air Force in Japan to conduct multiple aerial radiological surveys. These were the first and most comprehensive sources of actionable information for U.S. interests in Japan and provided early confirmation to the government of Japan as to the extent of the release from the Fukushima Daiichi Nuclear Power Generation Station. Many challenges were overcome quickly during the first 48 hours; including installation and operation of Aerial Measuring System equipment on multiple U.S. Air Force Japan aircraft, flying over difficultmore » terrain, and flying with talented pilots who were unfamiliar with the Aerial Measuring System flight patterns. These all combined to make for a dynamic and non-textbook situation. In addition, the data challenges of the multiple and on-going releases, and integration with the Japanese government to provide valid aerial radiological survey products that both military and civilian customers could use to make informed decisions, was extremely complicated. The Aerial Measuring System Fukushima response provided insight in addressing these challenges and gave way to an opportunity for the expansion of the Aerial Measuring System’s mission beyond the borders of the US.« less

  2. Resonance bonding in XNgY (X = F, Cl, Br, I; Ng = Kr or Xe; Y = CN or NC) molecules: an NBO/NRT investigation.

    PubMed

    Song, Junjie; Su, Yue; Jia, Yanping; Chen, Lusheng; Zhang, Guiqiu

    2018-05-07

    Several noble-gas-containing molecules XNgY were observed experimentally. However, the bonding in such systems is still not understood. Using natural bond orbital and natural resonance theory (NBO/NRT) methods, the present work investigated bonding of the title molecules. The results show that each of the studied XNgY molecules should be better described as a resonance hybrid of ω-bonding and [Formula: see text]-type long-bonding structures: X: - Ng +  - Y, X - Ng + : Y - , and X ^ Y. The ω-bonding and long-bonding make competing contributions to the composite resonance hybrid due to the accurately preserved bond order conservation principle. We find that the resonance bonding is highly tunable for these noble-gas-containing molecules due to its dependence on the nature of the halogen X or the central noble-gas atoms Ng. When the molecule XNgY consists of a relatively lighter Ng atom, a relatively low-electronegative X atom, and the CN fragment rather than NC, the long-bonding structure X ^ Y tends to be highlighted. In contrast, the heavy Ng atom and high-electronegative X atom will enhance the ω-bonding structure. Overall, the present work provides electronic principles and chemical insights that help understand the bonding in these XNgY species.

  3. Male acceptance of condoms in Japan.

    PubMed

    Uchida, Y

    1981-01-01

    Current surveys indicate that more than 70% of married couples in Japan use condoms as their primary contraceptive method. The popularity of condoms is due to the oral contraceptive (OC) pills not being recognized as safe forms of contraception and IUDs not being legalized by the government until 1974. The history of condom use in Japan goes back to 1872 when condoms of thin leather were imported into Japan from England and France. Manufacturing of condoms in Japan began in 1909, mainly as a method for venereal disease prevention. The condom and induced abortion are now the major methods of contraception. 60% of the distribution of condoms is through pharmacies and cosmetic stores; 50% of the buyers are women. Since 1955, teams of family planning workers have distributed condoms by selling on a door-to-door basis, especially to lower middle class couples. Between 1969-75, 75% of contraceptive users were using condoms. Currently there are 81% users. The rhythm method ranks second in popularity at 30% between 1969-75. OCs have gradually increased recently to 3% users, but side effects have deterred people from selecting them. The proportion of IUD users has remained at a consistently low level for the past several years. Japan accounts for 1/3 of the total world production of condoms.

  4. Increased reach and effectiveness of a statewide tobacco quitline after the addition of access to free nicotine replacement therapy

    PubMed Central

    An, Lawrence C; Schillo, Barbara A; Kavanaugh, Annette M; Lachter, Randi B; Luxenberg, Michael G; Wendling, Ann H; Joseph, Anne M

    2006-01-01

    Background Tobacco users receiving behavioural and pharmacological assistance are more likely to quit. Although telephone quitlines provide population access to counselling, few offer pharmacotherapy. Objective To assess change in cessation rates and programme impact after the addition of free nicotine replacement therapy (NRT) to statewide quitline services. Design, setting, participants An observational study of cohorts of callers to the Minnesota QUITPLANSM Helpline before (n  =  380) and after (n  =  373) the addition of access to free NRT. Intervention Mailing of NRT (patch or gum) to callers enrolling in multi‐session counselling. Main outcome measure Thirty‐day abstinence six months after programme registration. Results The number of callers increased from 155 (SD 75) to 679 (180) per month pre‐NRT to post‐NRT (difference 524, 95% confidence interval (CI) 323 to 725). Post‐NRT, the proportion of callers enrolling in multi‐session counselling (23.4% v 90.1%, difference 66.6%, 95% CI 60.8% to 71.6%) and using pharmacotherapy (46.8% v 86.8%, difference 40.0%, 95% CI 31.3% to 47.9%) increased. Thirty‐day abstinence at six months increased from 10.0% pre‐NRT to 18.2% post‐NRT (difference 8.2%, 95% CI 3.1% to 13.4%). Post‐NRT the average number of new ex‐smokers per month among registrants increased from 15.5 to 123.6 (difference 108.1, 95% CI 61.1 to 155.0). The cost per quit pre‐NRT was $1362 (SD $207). The cost per quit post‐NRT was $1934 ($215) suggesting a possible increase in cost per quit (difference $572, 95% CI −$12 to $1157). Conclusion The addition of free NRT to a state quitline is followed by increases in participation and abstinence rates resulting in an eightfold increase in programme impact. These findings support the addition of access to pharmacological therapy as part of state quitline services. PMID:16885577

  5. L-Band RFI in Japan

    NASA Technical Reports Server (NTRS)

    Soldo, Yan; de Matthaeis, Paolo; Le Vine, David M.

    2016-01-01

    In recent years, three instruments have been launched into orbit with the aim of producing global maps of sea surface salinity and soil moisture using the 1400-1427 MHz band: SMOS, Aquarius and SMAP. Although this frequency band is allocated to passive measurements only, RFI (Radio-Frequency Interference) is present in the data of all three missions. On a global scale, the three sensors have observed approximately the same distribution of RFI. Japan is an important exception that has implications for the design of RFI detection algorithms. RFI in Japan is caused by a large number of emitters belonging to the same system (TV receivers) and for this reason some traditional RFI detection strategies detect little to no RFI over Japan. The study of this case has led to an improvement of the approach to detect RFI in Aquarius data.

  6. An overview of work, retirement, and pensions in Japan.

    PubMed

    Bass, S A

    1996-01-01

    Work to retirement in Japan is a sequential transition for the most part, and Japan permits mandatory retirement by firms at age 60. But many older people work beyond the age of 60, many more than in other industrialized countries. A number of hypotheses are examined, having to do with pensions, health, opportunity, interest in working, cultural attitudes (including the concept of ikigai), and public policy initiatives (such as employment policy and the Silver Human Resource Centers). Japan's cultural attitudes and existing policies appear to have set Japan on a unique course in considering the aging of its population. To what extent should other nations emulate Japan?

  7. Barriers to mental health care in Japan: Results from the World Mental Health Japan Survey.

    PubMed

    Kanehara, Akiko; Umeda, Maki; Kawakami, Norito

    2015-09-01

    The reasons for accessing and maintaining access to mental health services in Japan may be different to those in other countries. Using the World Health Organization World Mental Health Japan survey data, this study investigated the prevalence of sociodemographic correlates of barriers for the use of, reasons for delayed access to, and reasons for dropping out from mental health care in a Japanese community-based sample. An interview survey was conducted with a random sample of residents living in 11 communities across Japan during the years 2002-2006. Data from 4130 participants were analyzed. The most frequently reported reason for not seeking mental health care was a low perceived need (63.9%). The most common reason for delaying access to help was the wish to handle the problem on one's own (68.8%), while the most common reason for dropping out of care was also a low perceived need (54.2%). Being a woman and of younger age were key sociodemographic barriers to the use of mental health services. Low perceived need was a major reason for not seeking, delay in using, and dropout from mental health services in Japan. In addition, low perceived need and structural barriers were more frequently reported than attitudinal barriers, with the exception of a desire to handle the problem on one's own. These findings suggest that improving therapist-patient communication and quality of mental health care, as well as mental health literacy education in the community, might improve access to care in Japan. © 2014 The Authors. Psychiatry and Clinical Neurosciences © 2014 Japanese Society of Psychiatry and Neurology.

  8. Outdoor Education and Camping in Japan.

    ERIC Educational Resources Information Center

    Ebashi, Shinshiro

    Professor Shinshiro Ebashi of the University of Tokyo discusses outdoor education in Japan, especially in relation to legislation (e.g., the Sport Promotion Law of 1961) and programs endorsed by the Ministry of Education. A typical outdoor education program for junior-high students is given. Also discussed are the programs of the All Japan Senior…

  9. Words of Tohkaku Wada: medical heritage in Japan

    PubMed Central

    Matsumoto, M.; Inoue, K.; Kajii, E.

    2001-01-01

    The origins of Japan's medical ideas, which are deeply rooted in its religion, culture and history, are not widely understood in medical societies of other countries. We have taken up the task of summarising this tradition here so that some insight can be gained into the unique issues that characterise the practice of medicine in Japan. We borrow from the sayings of Tohkaku Wada, a medical philosopher of late eighteenth-century Japan, for a look at Japanese medical tradition. Wada's medical thought was very much reflective of the Buddhism, Zen, and swordsmanship that informed eighteenth-century philosophy in Japan. His central concepts were "chu" and "sei", that is, complete and selfless dedication to the patient and the practice of medicine. This paper explores Wada's thought, explaining it mainly from the standpoint of Japanese traditional culture. Key Words: Tohkaku Wada • ethics • philosophy • Buddhism • Zen • Japan PMID:11233381

  10. A prospective earthquake forecast experiment for Japan

    NASA Astrophysics Data System (ADS)

    Yokoi, Sayoko; Nanjo, Kazuyoshi; Tsuruoka, Hiroshi; Hirata, Naoshi

    2013-04-01

    One major focus of the current Japanese earthquake prediction research program (2009-2013) is to move toward creating testable earthquake forecast models. For this purpose we started an experiment of forecasting earthquake activity in Japan under the framework of the Collaboratory for the Study of Earthquake Predictability (CSEP) through an international collaboration. We established the CSEP Testing Centre, an infrastructure to encourage researchers to develop testable models for Japan, and to conduct verifiable prospective tests of their model performance. On 1 November in 2009, we started the 1st earthquake forecast testing experiment for the Japan area. We use the unified JMA catalogue compiled by the Japan Meteorological Agency as authorized catalogue. The experiment consists of 12 categories, with 4 testing classes with different time spans (1 day, 3 months, 1 year, and 3 years) and 3 testing regions called All Japan, Mainland, and Kanto. A total of 91 models were submitted to CSEP-Japan, and are evaluated with the CSEP official suite of tests about forecast performance. In this presentation, we show the results of the experiment of the 3-month testing class for 5 rounds. HIST-ETAS7pa, MARFS and RI10K models corresponding to the All Japan, Mainland and Kanto regions showed the best score based on the total log-likelihood. It is also clarified that time dependency of model parameters is no effective factor to pass the CSEP consistency tests for the 3-month testing class in all regions. Especially, spatial distribution in the All Japan region was too difficult to pass consistency test due to multiple events at a bin. Number of target events for a round in the Mainland region tended to be smaller than model's expectation during all rounds, which resulted in rejections of consistency test because of overestimation. In the Kanto region, pass ratios of consistency tests in each model showed more than 80%, which was associated with good balanced forecasting of event

  11. 2012/13 abnormal cold winter in Japan associated with Large-scale Atmospheric Circulation and Local Sea Surface Temperature over the Sea of Japan

    NASA Astrophysics Data System (ADS)

    Ando, Y.; Ogi, M.; Tachibana, Y.

    2013-12-01

    On Japan, wintertime cold wave has social, economic, psychological and political impacts because of the lack of atomic power stations in the era of post Fukushima world. The colder winter is the more electricity is needed. Wintertime weather of Japan and its prediction has come under the world spotlight. The winter of 2012/13 in Japan was abnormally cold, and such a cold winter has persisted for 3 years. Wintertime climate of Japan is governed by some dominant modes of the large-scale atmospheric circulations. Yasunaka and Hanawa (2008) demonstrated that the two dominant modes - Arctic Oscillation (AO) and Western Pacific (WP) pattern - account for about 65% of the interannual variation of the wintertime mean surface air temperature of Japan. A negative AO brings about cold winter in Japan. In addition, a negative WP also brings about cold winter in Japan. Looking back to the winter of 2012/13, both the negative AO and negative WP continued from October through December. If the previous studies were correct, it would have been extremely very cold from October through December. In fact, in December, in accordance with previous studies, it was colder than normal. Contrary to the expectation, in October and November, it was, however, warmer than normal. This discrepancy signifies that an additional hidden circumstance that heats Japan overwhelms these large-scale atmospheric circulations that cool Japan. In this study, we therefore seek an additional cause of wintertime climate of Japan particularly focusing 2012 as well as the AO and WP. We found that anomalously warm oceanic temperature surrounding Japan overwhelmed influences of the AO or WP. Unlike the inland climate, the island climate can be strongly influenced by surrounding ocean temperature, suggesting that large-scale atmospheric patterns alone do not determine the climate of islands. (a) Time series of a 5-day running mean AO index (blue) as defined by Ogi et al., (2004), who called it the SVNAM index. For

  12. The Bioterrorism Threat by Non-State Actors: Hype or Horror?

    DTIC Science & Technology

    2006-12-01

    renamed the town Rajneesh. It took control over the local schools while also converting the only local business into a vegetarian restaurant called...multiple targets. The April 1990 attack was perpetrated from three trucks at multiple locations. The cult targeted Narita Airport, the Diet , the

  13. Learning by the Aged in Japan.

    ERIC Educational Resources Information Center

    Sekiguchi, Reiko W.

    This paper discusses demographic changes in Japan, the sources of pleasure of the retired Japanese senior citizen, and lifelong learning. It also describes a study that examined learning preferences of Japanese senior citizens. Data for 1983 show that life expectancy has increased in Japan to 74.20 years for males and 79.78 for females. The level…

  14. The impact of changing nicotine replacement therapy licensing laws in the United Kingdom: findings from the International Tobacco Control Four Country Survey.

    PubMed

    Shahab, Lion; Cummings, K Michael; Hammond, David; Borland, Ron; West, Robert; McNeill, Ann

    2009-08-01

    To evaluate the impact of a new licence for some nicotine replacement therapy products (NRT) for cutting down to stop (CDTS) on changes in the pattern of NRT use. Quasi-experimental design comparing changes in NRT use across two waves of a population-based, replenished-panel, telephone survey conducted before and after the introduction of new licensing laws in the United Kingdom with changes in NRT use in three comparison countries (Australia, Canada and United States) without a licensing change. A total of 7386 and 7013 smokers and recent ex-smokers participating in the 2004 and/or 2006/7 survey. Data were collected on demographic and smoking characteristics as well as NRT use and access. In order to account for interdependence resulting from some participants being present in both waves, generalized estimation equations with an exchangeable correlation matrix were used to assess within-country changes and linear and logistic regressions to assess between-country differences in adjusted analyses. NRT use was more prevalent in the United Kingdom and increased across waves in all countries but no wave x country interaction was observed. There was no evidence that the licensing change increased the prevalence of CDTS or the use of NRT (irrespective of how it was accessed) for CDTS in the United Kingdom relative to comparison countries. There was also no evidence for a change in concurrent smoking and NRT use among smokers not attempting to stop in the United Kingdom relative to comparison countries. The addition of the CDTS licence for some NRT products in the United Kingdom appears to have had very limited, if any, impact on NRT use in the first year after the licence change.

  15. A retrospective analysis of the association between providing nicotine replacement therapy at admission and motivation to quit and nicotine withdrawal symptoms during an inpatient psychiatric hospitalization.

    PubMed

    Okoli, Chizimuzo T C; Al-Mrayat, Yazan D; Shelton, Charles I; Khara, Milan

    2018-06-07

    Psychiatric patients have high tobacco use prevalence, dependence, and withdrawal severity. A tobacco-free psychiatric hospitalization necessitates the management of nicotine withdrawal (NW) for tobacco using patients. NW management often requires the provision of approved nicotine replacement therapy (NRT) to patients, which may also motivate tobacco users towards cessation. However, few studies have examined the associations between providing NRT, motivation to quit, and NW among psychiatric patients. To examine the associations between providing NRT at admission and motivation to quit smoking and severity of NW symptoms. A retrospective review of the medical records of 255 tobacco using patients on whom NW was assessed during their hospital stay. The time when NRT was provided (i.e., at admission vs. not provided vs. on the unit), motivation to quit smoking, and 8-item Minnesota Nicotine Withdrawal Scale were assessed. The primary NW symptom was 'craving' (65.1%); reporting of 'anxiety' varied by psychiatric diagnosis. Providing NRT at admission was not associated with motivation to quit. Patients receiving NRT on the unit (i.e., delayed receipt) had significantly higher NW than those who received NRT at admission. In multivariate analyses, receiving NRT on the unit was significantly associated with greater NW severity (β = .19, p = .002). Among psychiatric patients, providing NRT at admission is associated with greater severity of NW. The provision of NRT for NW management may be considered as standard practice during tobacco-free psychiatric stays. Future studies may consider the effect of other tobacco treatment medications (such as varenicline, bupropion) on managing NW. Copyright © 2018 Elsevier Ltd. All rights reserved.

  16. Economic Factors of Japan’s National Security Policy

    DTIC Science & Technology

    1988-06-01

    34Japan bashers " have been eager to retaliate with protectionist trade legislation. Japan has been criticized by free-market strategists and frustrated...exercise served to quiet Japan- bashers and defuse protectionist sentiments in Congress. Even more important, defeat of a retaliatory bill based on general

  17. Understanding and use of nicotine replacement therapy and nonpharmacologic smoking cessation strategies among Chinese and Vietnamese smokers and their families.

    PubMed

    Tsang, Icarus K; Tsoh, Janice Y; Wong, Ching; Le, Khanh; Cheng, Joyce W; Nguyen, Anthony N; Nguyen, Tung T; McPhee, Stephen J; Burke, Nancy J

    2014-02-20

    Population-based studies have reported high rates of smoking prevalence among Chinese and Vietnamese American men. Although nicotine replacement therapy (NRT) is effective, recommended, and accessible without prescription, these populations underuse NRT for smoking cessation. The aim of this study was to assess understanding and use of NRT and nonpharmacologic treatments among Chinese and Vietnamese American male smokers and their families. In-depth qualitative interviews were conducted with 13 smoker-family pairs, followed by individual interviews with each participant. A total of 39 interviews were conducted in Vietnamese or Chinese, recorded, translated, and transcribed into English for analysis. Four themes were identified: use and understanding of NRT, nonpharmacologic strategies, familial and religious approaches, and willpower. Both smokers and their family members believed strongly in willpower and a sense of personal responsibility as the primary drivers for stopping smoking. Lack of these 2 qualities keeps many Chinese and Vietnamese men from using NRT to quit smoking. Those who do use NRT often use it incorrectly, following their own preferences rather than product instructions. Our findings indicate the importance of culturally appropriate patient education about NRT. It may be necessary to teach smokers and their families at an individual level about NRT as a complementary approach that can strengthen their resolve to quit smoking. At a community level, public health education on the indication and appropriate use of evidence-based smoking cessation resources, such as NRT, would be an important component of effective tobacco control.

  18. Nicotine replacement prescribing trends in a large psychiatric hospital, before and after implementation of a hospital-wide smoking ban.

    PubMed

    Scharf, Deborah; Fabian, Tanya; Fichter-DeSando, Cecilia; Douaihy, Antoine

    2011-06-01

    We examined prescribing patterns for nicotine replacement therapies (NRTs) in a large psychiatric hospital, before and after the implementation of a smoking ban. We extracted 5 years of NRT utilization data from hospital pharmacy records. The ban went into effect on January 1, 2007. Data reflect NRT prescriptions from 2 years before and 3 years after the ban, and N = 30,908 total inpatient hospital admissions. The monthly rate of total NRT prescriptions increased after the ban from M = 254.25 (SD = 126.60) doses per month to M = 4,467.52 (SD = 1,785.87) doses per month (>1,700% increase, p < .0001). After the smoking ban, clinicians prescribed higher doses of transdermal (but not oral) NRT (Tukey, p < .0001). Comparisons of NRT prescribing across hospital units tentatively suggested that patients being treated on the substance use disorders unit were prescribed more doses of NRT, as well as higher doses of NRT compared with patients on other units. Analysis of trends over time showed no apparent downward trend for NRT usage during the 3 years following the smoking ban, suggesting that clinicians continued to treat nicotine dependence after smoking was restricted. Clinicians are more likely to identify and treat symptoms of nicotine withdrawal when smoking is restricted. Hospitals should consider monitoring prescriptions for NRT as part of their ongoing quality assurance practices so that patients receive aggressive treatment of nicotine withdrawal symptoms--an essential component of high-quality patient care.

  19. Lessons learned from the implementation of a time-limited, large-scale nicotine replacement therapy giveaway program in New York City.

    PubMed

    Davis, Karen A; Coady, Micaela H; Mbamalu, Ijeoma G; Sacks, Rachel; Kilgore, Elizabeth A

    2013-09-01

    Since 2006, the New York City (NYC) Department of Health and Mental Hygiene has conducted the Nicotine Patch and Gum Program (NPGP) in collaboration with 311, NYC's non-emergency information line. In two prior years, the program was conducted in collaboration with the New York State (NYS) Smokers' Quitline and with community-based organizations. The NPGP is an annual, brief, population-based nicotine replacement therapy (NRT) giveaway for NYC residents, complementing the NYS Quitline's year-round NRT distribution program. Since 2006, 168,000 smokers have enrolled, with the largest number of enrollees in 2010 (n = 40,000) and the smallest number in 2009 (n = 28,000). A 2003 program evaluation demonstrated that smokers who received NRT through the NPGP had higher quit rates than smokers who did not receive NRT; these results were replicated in 2006 and 2008. Lessons learned from implementing the NPGP include: 1) time-limited NRT interventions are important complements to year-round NRT distribution; 2) expanding NRT distribution to light smokers increases treatment reach; and 3) employing multiple enrollment mechanisms, including telephone and online options, extends program reach to diverse groups of smokers. The NPGP provides a model for other jurisdictions considering implementing time-limited, population-based NRT programs as a complementary strategy to enhance ongoing tobacco control efforts.

  20. A systematic review of possible serious adverse health effects of nicotine replacement therapy.

    PubMed

    Lee, Peter N; Fariss, Marc W

    2017-04-01

    We conducted a systematic literature review to identify and critically evaluate studies of serious adverse health effects (SAHEs) in humans using nicotine replacement therapy (NRT) products. Serious adverse health effects refer to adverse events, leading to substantial disruption of the ability to conduct normal life functions. Strength of evidence evaluations and conclusions were also determined for the identified SAHEs. We evaluated 34 epidemiological studies and clinical trials, relating NRT use to cancer, reproduction/development, CVD, stroke and/or other SAHEs in patients, and four meta-analyses on effects in healthy populations. The overall evidence suffers from many limitations, the most significant being the short-term exposure (≤12 weeks) and follow-up to NRT product use in most of the studies, the common failure to account for changes in smoking behaviour following NRT use, and the sparse information on SAHEs by type of NRT product used. The only SAHE from NRT exposure we identified was an increase in respiratory congenital abnormalities reported in one study. Limited evidence indicated a lack of effect between NRT exposure and SAHEs for CVD and various reproduction/developmental endpoints. For cancer, stroke and other SAHEs, the evidence was inadequate to demonstrate any association with NRT use. Our conclusions agree with recent statements from authoritative bodies.

  1. 75 FR 57980 - Polychloroprene Rubber From Japan

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-23

    ... INTERNATIONAL TRADE COMMISSION [Investigation No. AA1921-129 (Third Review)] Polychloroprene Rubber From Japan AGENCY: United States International Trade Commission. ACTION: Termination of five-year... of the antidumping duty finding on polychloroprene rubber from Japan would be likely to lead to...

  2. Disparities in Access to Over-the-Counter Nicotine Replacement Products in New York City Pharmacies

    PubMed Central

    Cabral, Lisa; Maantay, Juliana; Peprah, Dorothy; Lounsbury, David; Maroko, Andrew; Murphy, Mary; Shelley, Donna

    2009-01-01

    Objectives. We surveyed the availability of tobacco products and nonprescription nicotine replacement therapy (NRT) in pharmacies in New York City, stratified by the race, ethnicity, and socioeconomic status (SES) of the surrounding neighborhoods to determine whether disparities in availability existed. Methods. Surveyors visited a random sample of retail pharmacies to record the availability of tobacco products and nonprescription NRT. We used census data and geographic information systems analysis to determine the SES of each neighborhood. We used logistic modeling to explore relations between SES and the availability of NRT and tobacco products. Results. Of 646 pharmacies sampled, 90.8% sold NRT and 46.9% sold cigarettes. NRT and cigarettes were slightly more available in pharmacies in neighborhoods with a higher SES. NRT was more expensive in poorer neighborhoods. Conclusions. Small disparities existed in access to nonprescription NRT and cigarettes. The model did not adequately account for cigarette access, because of availability from other retail outlets. These results may explain some of the excess prevalence of cigarette use in low-SES areas. PMID:19638596

  3. Genetic divergence in nuclear genomes between populations of Fagus crenata along the Japan Sea and Pacific sides of Japan.

    PubMed

    Hiraoka, Koichi; Tomaru, Nobuhiro

    2009-05-01

    Genetic diversity and structure in Fagus crenata were studied by analyzing 14 nuclear microsatellite loci in 23 populations distributed throughout the species' range. Although population differentiation was very low (F (ST) = 0.027; R (ST) = 0.041), both neighbor-joining tree and Bayesian clustering analyses provided clear evidence of genetic divergence between populations along the Japan Sea (Japan Sea lineage) and Pacific (Pacific lineage) sides of Japan, indicating that physical barriers to migration and gene flow, notably the mountain ranges separating the populations along the Japan Sea and Pacific sides, have promoted genetic divergence between these populations. The two lineages of the nuclear genome are generally consistent with those of the chloroplast genome detected in a previous study, with several discrepancies between the two genomes. Within-population genetic diversity was generally very high (average H (E) = 0.839), but decreased in a clinal fashion from southwest to northeast, largely among populations of the Japan Sea lineage. This geographical gradient may have resulted from the late-glacial and postglacial recolonization to the northeast, which led to a loss of within-population genetic diversity due to cumulative founder effects.

  4. JTEC panel report on machine translation in Japan

    NASA Technical Reports Server (NTRS)

    Carbonell, Jaime; Rich, Elaine; Johnson, David; Tomita, Masaru; Vasconcellos, Muriel; Wilks, Yorick

    1992-01-01

    The goal of this report is to provide an overview of the state of the art of machine translation (MT) in Japan and to provide a comparison between Japanese and Western technology in this area. The term 'machine translation' as used here, includes both the science and technology required for automating the translation of text from one human language to another. Machine translation is viewed in Japan as an important strategic technology that is expected to play a key role in Japan's increasing participation in the world economy. MT is seen in Japan as important both for assimilating information into Japanese as well as for disseminating Japanese information throughout the world. Most of the MT systems now available in Japan are transfer-based systems. The majority of them exploit a case-frame representation of the source text as the basis of the transfer process. There is a gradual movement toward the use of deeper semantic representations, and some groups are beginning to look at interlingua-based systems.

  5. Healthcare in Japan: its professionals, institutions, and financing.

    PubMed

    Al-Assaf, A F; Payne, J

    1991-01-01

    Like the United States, Japan's healthcare system is a conglomerate of government, employer, and individual financing--but that's about as far as the similarity goes. Universal access to basic healthcare has been achieved in Japan through comprehensive employer/employee plans and government subsidies. However, the United States should not be too hasty in emulating Japan, for culture plays a definite role in healthcare on both sides of the Pacific.

  6. Teaching Primary School Children about Japan through Art. ERIC Digest.

    ERIC Educational Resources Information Center

    Ward, Patricia Berg

    There are a variety reasons for teaching about Japan. Many students in the United States are of Japanese heritage; Japan is the second largest trading partner of the United States; and some healing still needs to occur between the United States and Japan because of the damage and pain of World War II. Further, the Unites States and Japan share the…

  7. Divorce in contemporary Japan.

    PubMed

    Fukurai, H; Alston, J

    1990-10-01

    Data from the 1985-86 Japanese census are analysed to explore the determinants of the divorce rates in Japan's forty-seven prefectures, using two theoretical models: (a) the social integration model, which is shown to have a greater utility in predicting Japanese divorce levels than (b), the human capital model. Female emigration patterns play a significant role in affecting the divorce rate. Population increase and net household income are also important predictors of the Japanese divorce rate and urbanization has a great influence in modern Japan. Demographic and aggregate variables such as migration, urbanization, and socioeconomic factors are useful when organized under a social integration model.

  8. Japan: International Perspectives on Business Communication Research.

    ERIC Educational Resources Information Center

    Nakasako, Shun-Itsu

    1998-01-01

    Discusses research developments in business communication in Japan from the early 1900s to present. Describes early interest in business English; the emergence of business communication; business communication as a broad and interdisciplinary research field in Japan; and its impact on teaching. (SR)

  9. Should Japan Become a Normal Country

    DTIC Science & Technology

    2005-12-01

    9 B. ANCIENT JAPAN: ORIGINS AND ASUKA, NARA, AND HEIAN PERIODS...ANCIENT JAPAN: ORIGINS AND ASUKA, NARA, AND HEIAN PERIODS Japanese culture emerged on Yamato plain around the 2nd and 3rd centuries A.D. and continued...record of ancient matters.22 Immediately following this era was the Heian period during which the imperial court moved to a new, permanent capital

  10. 78 FR 7451 - Clad Steel Plate From Japan; Determination

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-01

    ... Japan; Determination On the basis of the record \\1\\ developed in the subject five-year review, the... from Japan would be likely to lead to continuation or recurrence of material injury to an industry in... USITC Publication 4370 (January 2013), entitled Clad Steel Plate from Japan: Investigation No. 731-TA...

  11. Literacy in Japan.

    ERIC Educational Resources Information Center

    Kanaya, Toshio

    1979-01-01

    Examines three causes for Japan's high literacy rate: (1) emphasis on literacy in Japanese society; (2) pervasive effect of the modern Japanese school system; (3) special structural features of the Japanese language which aid in functional use. (DR)

  12. 78 FR 66767 - Chlorinated Isocyanurates From China and Japan

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-06

    ...)] Chlorinated Isocyanurates From China and Japan Determinations On the basis of the record \\1\\ developed in the... reason of imports from China and Japan of chlorinated isocyanurates, provided for in subheadings 2933.69... (LTFV) from Japan and subsidized by the Government of China.\\2\\ \\1\\ The record is defined in sec. 207.2...

  13. GABAB receptor-mediated responses in GABAergic projection neurones of rat nucleus reticularis thalami in vitro.

    PubMed

    Ulrich, D; Huguenard, J R

    1996-06-15

    1. Whole-cell voltage-clamp recordings were obtained from GABAergic neurones of rat nucleus reticularis thalami (NRT) in vitro to assess pre- and postsynaptic GABAB receptor-mediated responses. Presynaptic inhibition of GABA release was studied at terminals on local axon collaterals within NRT as well as on projection fibres in the somatosensory relay nuclei. 2. The GABAB receptor agonist (R)-baclofen (10 microM) reduced monosynaptically evoked GABAA-mediated inhibitory postsynaptic currents (IPSCs) in NRT and somatosensory relay cells to 11 and 12% of control, respectively. 3. Action potential-independent miniature IPSCs (mIPSCs) were observed in both cell types. Mean mIPSC amplitude was 20 pA in both NRT and relay cells at a holding potential of 0 mV. The mean mIPSC frequencies were 0.83 and 2.2 Hz in NRT and relay cells, respectively. Baclofen decreased mIPSP frequency by about half in each cell type without affecting amplitude. 4. Paired-burst inhibition of evoked IPSCs was studied in relay and NRT cells by applying pairs of 100 Hz stimulus bursts separated by 600 ms. The mean ratio of second to first peak IPSC amplitudes was 0.77. 5. In NRT cells baclofen induced a linear postsynaptic conductance increase of 0.82 nS with an associated reversal potential of -121 mV. A small (0.14 nS) GABAB component of the evoked IPSC was detected in only a minority of NRT cells (3 of 18). 6. All pre- and postsynaptic effects of baclofen, as well as PBI, were largely reversed by the specific GABAB receptor antagonist CGP 35348 (0.5 mM). 7. We conclude that activation of GABAB receptors in NRT leads to presynaptic autoinhibition of IPSCs in both NRT and relay cells, and to direct activation of a small linear K+ conductance. In addition our experiments suggest that reciprocal connectivity within NRT can be partially mediated by a small GABAB inhibitory event.

  14. Endocrine disorders and diabetes in Japan.

    PubMed

    Seino, Y; Imura, H

    1994-10-01

    The frequency of glucose intolerance including diabetes and IGT in endocrine diseases was compared between Japan and foreign countries. It was revealed that the frequency of diabetes in endocrine diseases is generally higher in Japan than in foreign countries. In addition, plasma insulin response to glucose was exaggerated in Cushing's syndrome with glucose intolerance, but was impaired in acromegaly and pheochromocytoma with glucose intolerance.

  15. People of Japan: Building Bridges of Understanding.

    ERIC Educational Resources Information Center

    Brigham Young Univ., Provo, UT. Language Research Center.

    This booklet was designed to facilitate interactions and communication with the people of Japan by providing information about their customs, attitudes and other cultural characteristics which influence their actions and values. A brief description of Japan is given, covering the following: history, government, the economy, education,…

  16. Knockdown of a Rice Stelar Nitrate Transporter Alters Long-Distance Translocation But Not Root Influx1[W][OA

    PubMed Central

    Tang, Zhong; Fan, Xiaorong; Li, Qing; Feng, Huimin; Miller, Anthony J.; Shen, Qirong; Xu, Guohua

    2012-01-01

    Root nitrate uptake is well known to adjust to the plant’s nitrogen demand for growth. Long-distance transport and/or root storage pools are thought to provide negative feedback signals regulating root uptake. We have characterized a vascular specific nitrate transporter belonging to the high-affinity Nitrate Transporter2 (NRT2) family, OsNRT2.3a, in rice (Oryza sativa ssp. japonica ‘Nipponbare’). Localization analyses using protoplast expression, in planta promoter-β-glucuronidase assay, and in situ hybridization showed that OsNRT2.3a was located in the plasma membrane and mainly expressed in xylem parenchyma cells of the stele of nitrate-supplied roots. Knockdown expression of OsNRT2.3a by RNA interference (RNAi) had impaired xylem loading of nitrate and decreased plant growth at low (0.5 mm) nitrate supply. In comparison with the wild type, the RNAi lines contained both nitrate and total nitrogen significantly higher in the roots and lower in the shoots. The short-term [15N]NO3− influx (5 min) in entire roots and NO3− fluxes in root surfaces showed that the knockdown of OsNRT2.3a in comparison with the wild type did not affect nitrate uptake by roots. The RNAi plants showed no significant changes in the expression of some root nitrate transporters (OsNRT2.3b, OsNRT2.4, and OsNAR2.1), but transcripts for nia1 (nitrate reductase) had increased and OsNRT2.1 and OsNRT2.2 had decreased when the plants were supplied with nitrate. Taken together, the data demonstrate that OsNRT2.3a plays a key role in long-distance nitrate transport from root to shoot at low nitrate supply level in rice. PMID:23093362

  17. History of Nuclear Fusion Research in Japan

    NASA Astrophysics Data System (ADS)

    Iguchi, Harukazu; Matsuoka, Keisuke; Kimura, Kazue; Namba, Chusei; Matsuda, Shinzaburo

    In the late 1950s just after the atomic energy research was opened worldwide, there was a lively discussion among scientists on the strategy of nuclear fusion research in Japan. Finally, decision was made that fusion research should be started from the basic, namely, research on plasma physics and from cultivation of human resources at universities under the Ministry of Education, Science and Culture (MOE). However, an endorsement was given that construction of an experimental device for fusion research would be approved sooner or later. Studies on toroidal plasma confinement started at Japan Atomic Energy Research Institute (JAERI) under the Science and Technology Agency (STA) in the mid-1960s. Dualistic fusion research framework in Japan was established. This structure has lasted until now. Fusion research activities over the last 50 years are described by the use of a flowchart, which is convenient to glance the historical development of fusion research in Japan.

  18. The impact of media campaigns on smoking cessation activity: a structural vector autoregression analysis.

    PubMed

    Langley, Tessa E; McNeill, Ann; Lewis, Sarah; Szatkowski, Lisa; Quinn, Casey

    2012-11-01

    To evaluate the effect of tobacco control media campaigns and pharmaceutical company-funded advertising for nicotine replacement therapy (NRT) on smoking cessation activity. Multiple time series analysis using structural vector autoregression, January 2002-May 2010. England and Wales. Tobacco control campaign data from the Central Office of Information; commercial NRT campaign data; data on calls to the National Health Service (NHS) stop smoking helpline from the Department of Health; point-of-sale data on over-the-counter (OTC) sales of NRT; and prescribing data from The Health Improvement Network (THIN), a database of UK primary care records. Monthly calls to the NHS stop smoking helpline and monthly rates of OTC sales and prescribing of NRT. A 1% increase in tobacco control television ratings (TVRs), a standard measure of advertising exposure, was associated with a statistically significant 0.085% increase in calls in the same month (P = 0.007), and no statistically significant effect in subsequent months. Tobacco control TVRs were not associated with OTC NRT sales or prescribed NRT. NRT advertising TVRs had a significant effect on NRT sales which became non-significant in the seasonally adjusted model, and no significant effect on prescribing or calls. Tobacco control campaigns appear to be more effective at triggering quitting behaviour than pharmaceutical company NRT campaigns. Any effect of such campaigns on quitting behaviour seems to be restricted to the month of the campaign, suggesting that such campaigns need to be sustained over time. © 2012 The Authors, Addiction © 2012 Society for the Study of Addiction.

  19. Understanding and Use of Nicotine Replacement Therapy and Nonpharmacologic Smoking Cessation Strategies Among Chinese and Vietnamese Smokers and Their Families

    PubMed Central

    Tsang, Icarus K.; Wong, Ching; Le, Khanh; Cheng, Joyce W.; Nguyen, Anthony N.; Nguyen, Tung T.; McPhee, Stephen J.; Burke, Nancy J.

    2014-01-01

    Introduction Population-based studies have reported high rates of smoking prevalence among Chinese and Vietnamese American men. Although nicotine replacement therapy (NRT) is effective, recommended, and accessible without prescription, these populations underuse NRT for smoking cessation. The aim of this study was to assess understanding and use of NRT and nonpharmacologic treatments among Chinese and Vietnamese American male smokers and their families. Methods In-depth qualitative interviews were conducted with 13 smoker–family pairs, followed by individual interviews with each participant. A total of 39 interviews were conducted in Vietnamese or Chinese, recorded, translated, and transcribed into English for analysis. Results Four themes were identified: use and understanding of NRT, nonpharmacologic strategies, familial and religious approaches, and willpower. Both smokers and their family members believed strongly in willpower and a sense of personal responsibility as the primary drivers for stopping smoking. Lack of these 2 qualities keeps many Chinese and Vietnamese men from using NRT to quit smoking. Those who do use NRT often use it incorrectly, following their own preferences rather than product instructions. Conclusion Our findings indicate the importance of culturally appropriate patient education about NRT. It may be necessary to teach smokers and their families at an individual level about NRT as a complementary approach that can strengthen their resolve to quit smoking. At a community level, public health education on the indication and appropriate use of evidence-based smoking cessation resources, such as NRT, would be an important component of effective tobacco control. PMID:24556252

  20. Delays in clinical development of neurological drugs in Japan.

    PubMed

    Ikeda, Masayuki

    2017-06-28

    The delays in the approval and development of neurological drugs between Japan and other countries have been a major issue for patients with neurological diseases. The objective of this study was to analyze factors contributing to the delay in the launching of neurological drugs in Japan. We analyzed data from Japan and the US for the approval of 42 neurological drugs, all of which were approved earlier in the US than in Japan, and examined the potential factors that may cause the delay of their launch. Introductions of the 42 drugs in Japan occurred at a median of 87 months after introductions in the US. The mean review time of new drug applications for the 20 drugs introduced in Japan in January 2011 or later (15 months) was significantly shorter than that for the other 22 drugs introduced in Japan in December 2010 or earlier (24 months). The lag in the Japan's review time behind the US could not explain the approval delays. In the 31 of the 42 drugs, the application data package included overseas data. The mean review time of these 31 drugs (17 months) was significantly shorter than that of the other 11 drugs without overseas data (26 months). The mean approval lag behind the US of the 31 drugs (78 months) was also significantly shorter than that of the other 11 drugs (134 months). These results show that several important reforms in the Japanese drug development and approval system (e.g., inclusion of global clinical trial data) have reduced the delays in the clinical development of neurological drugs.

  1. Use of the Physiotherapy Evidence Database (PEDro) in Japan

    PubMed Central

    TAKASAKI, Hiroshi; ELKINS, Mark R.; MOSELEY, Anne M.

    2016-01-01

    Background: The Physiotherapy Evidence Database (PEDro) may help users to overcome some obstacles to evidence-based physiotherapy. Understanding the extent to which Japanese physiotherapists access research evidence via the PEDro website may suggest strategies to enhance evidence-based physiotherapy in Japan. Objectives: To quantify usage of PEDro in Japan, to compare this to usage in other countries, and to examine variations in PEDro usage within Japan. Design: An observational study of PEDro usage with geographic analysis. Methods: Data about visits to the home-page and searches of the database were recorded for 4 years. These data were analysed by each region of the World Confederation for Physical Therapy, each country in the Asia Western Pacific region, and each prefecture in Japan. Results: From 2010 to 2013, users of PEDro made 2.27 million visits to the home-page and ran 6.28 million searches. Usage (ie, number of searches normalised by population) was highest in Europe, followed by North America Carribean, South America, Asia Western Pacific, and Africa. Within the Asia Western Pacific region, population-normalised usage was highest in Australia, then New Zealand and Singapore. Japan ranked 10 among the 26 countries in the region. Within Japan, the highest population-normalised usage was in the Nagano, Kumamoto and Aomori prefectures, which was ten-fold higher usage than in some other prefectures. Conclusions: Although Japan has higher PEDro usage than many other countries in the Asia Western Pacific region, some prefectures had very low usage, suggesting that evidence-based practice may not be being adopted uniformly across Japan. PMID:28289582

  2. Coronary Artery Calcification in Japanese Men in Japan and Hawaii

    PubMed Central

    Abbott, Robert D.; Ueshima, Hirotsugu; Rodriguez, Beatriz L.; Kadowaki, Takashi; Masaki, Kamal H.; Willcox, Bradley J.; Sekikawa, Akira; Kuller, Lewis H.; Edmundowicz, Daniel; Shin, Chol; Kashiwagi, Atsunori; Nakamura, Yasuyuki; El-Saed, Aiman; Okamura, Tomonori; White, Roger; Curb, J. David

    2013-01-01

    Explanations for the low prevalence of atherosclerosis in Japan versus United States are often confounded with genetic variation. To help remove such confounding, coronary artery calcification (CAC), a marker of subclinical atherosclerosis, was compared between Japanese men in Japan and Japanese men in Hawaii. Findings are based on risk factor and CAC measurements that were made from 2001 to 2005 in 311 men in Japan and 300 men in Hawaii. Men were aged 40 to 50 years and without cardiovascular disease. After age-adjustment, there was a 3-fold excess in the odds of prevalent CAC scores ≥10 in Hawaii versus Japan (relative odds [RO] = 3.2; 95% confidence interval [CI] = 2.1,4.9). While men in Hawaii had a generally poorer risk factor profile, men in Japan were 4-times more likely to smoke cigarettes (49.5 vs. 12.7%, p<0.001). In spite of marked risk factor differences between the samples, none of the risk factors provided an explanation for the low amounts of CAC in Japan. After risk factor adjustment, the RO of CAC scores ≥10 in Hawaii versus Japan was 4.0 (95% CI = 2.2,7.4). Further studies are needed to identify factors that offer protection against atherosclerosis in Japanese men in Japan. PMID:17728270

  3. Getah Virus Infection among Racehorses, Japan, 2014

    PubMed Central

    Bannai, Hiroshi; Tsujimura, Koji; Kobayashi, Minoru; Kikuchi, Takuya; Yamanaka, Takashi; Kondo, Takashi

    2015-01-01

    An outbreak of Getah virus infection occurred among racehorses in Japan during September and October 2014. Of 49 febrile horses tested by reverse transcription PCR, 25 were positive for Getah virus. Viruses detected in 2014 were phylogenetically different from the virus isolated in Japan in 1978. PMID:25898181

  4. Japan's Winning Margins. Management, Training, and Education.

    ERIC Educational Resources Information Center

    Lorriman, John; Kenjo, Takashi

    This book explains the fundamental reasons for Japan's astonishing commercial success in relation to its Western competitors. Chapter 1 is an introduction. Chapter 2 discusses implications of Japanese history for education, training, and management. Chapter 3 looks at the first winning margin--education. It covers the following: Japan's long…

  5. Japan and the Soviet Threat: Perceptions and Reactions.

    DTIC Science & Technology

    1983-12-01

    s...nce the late 1970’s. This _training cannot but help elevate the defense readiness posture of Japan and based on the scenarios being exercised , the...supersonic low flyers, can be easily jammed, and are virtually unprotected (as are Japan’s air bases ). Though work is underway to improve BADGE, it will...opposition to Japanese plans in East Asia, Japan moved to improve its position by concluding a Neutrality Pact with le. .the USSR (1941). .5 The Soviets

  6. Neuroreflexotherapy for nonspecific low back pain: a systematic review.

    PubMed

    Urrútia, Gerard; Burton, Kim; Morral, Antoni; Bonfill, Xavier; Zanoli, Gustavo

    2005-03-15

    Systematic review. To assess the effectiveness of neuroreflexotherapy (NRT) for low back pain (LBP). Few of the alternatives for the management of LBP have a firm base of evidence for their effectiveness. Recently, a new intervention known as NRT has been developed in Spain and has been reported to have favorable results. Searches were undertaken according to Cochrane Collaboration guidelines, and randomized controlled trials that evaluated NRT as treatment for patients with nonspecific LBP were included. A qualitative synthesis and an assessment of methodological quality were undertaken. Three randomized controlled trials were included, with 125 and 148 subjects in control and intervention groups, respectively. NRT was compared with sham in two trials and standard care in one. Individuals receiving active NRT showed significantly better outcomes for pain, mobility, disability, medication use, consumption of resources, and costs. No major side effects were reported by those receiving active NRT. NRT appears to be a safe and effective intervention for nonspecific LBP. This conclusion is limited to three trials conducted by a small number of experienced clinicians. Further trials in other settings are needed to determine whether these favorable results can be generalized.

  7. Identification and expression analyses of two genes encoding putative low-affinity nitrate transporters from Nicotiana plumbaginifolia.

    PubMed

    Fraisier, V; Dorbe, M F; Daniel-Vedele, F

    2001-01-01

    Higher plants have both high- and low-affinity nitrate uptake systems (HATS and LATS respectively). Here we report the isolation and characterization of two genes, NpNRT1.1 and NpNRT1.2, from Nicotiana plumbaginifolia whose structural features suggest that they both belong to the NRT1 gene family, which is involved in the LATS. Amino acid sequence alignment showed that the N. plumbaginifolia proteins have greater similarity to their corresponding tomato homologues than to each other. Genomic Southern blot analysis indicates that there are probably more than two members of this family in N. plumbaginifolia. Northern blot analysis shows that NpNRT1.2 expression is restricted strictly to roots, whereas NpNRT1.1, in addition to roots, is expressed at a basal level in all other plant organs. Likewise, differential expression in response to external treatments with various N sources was observed for these two genes: NpNRT1.1 can be considered as a constitutively expressed gene whereas NpNRT1.2 expression is dependent strictly on high nitrate concentrations. Finally, over-expression of a gene involved in the HATS does not lead to any modification of LATS gene expression.

  8. Childbirth in aristocratic households of Heian Japan.

    PubMed

    Andreeva, Anna

    2014-01-01

    This paper focuses on childbirth in Japan's aristocratic households during the Heian period (794-1185). Drawing on various sources, including court diaries, visual sources, literary records, and Japan's first medical collection, with its assortment of gynaecological and obstetric prescriptions, as well as Buddhist and other ritual texts, this short excursion into the cultural history of childbirth offers an insight into how childbirth was experienced and managed in Heian Japan. In particular, it addresses the variety of ideas, knowledge systems and professionals involved in framing and supporting the process of childbirth in elite households. In so doing, it casts light on the complex background of early Japanese medicine and healthcare for women.

  9. Introductory Overview of Stone Heritages in Japan

    NASA Astrophysics Data System (ADS)

    Kato, Hirokazu; Oikawa, Teruki; Fujita, Masayo; Yokoyama, Shunji

    2013-04-01

    As one contribution to 'Global Heritage Stone Resources' (GHSR), some stone heritages in Japan, which are nominated in the interim list, are briefly introduced. The geology of Japanese Islands where are the one of the most active areas in the history of the Earth, is very complicated. Therefore Japanese Islands consist of various kinds of minerals and rocks. Some of them were used to make stone implements and accessories. Japanese people also used to the best possible advantage to built tombstone, gate, pavement ,and the basement and wall of the large building such as temples, shrines, castles and modern buildings. 1. Stone Heritages of Pre-historical age: In the late Pleistocene and the early Holocene, ancient Japanese used obsidian cooled rapidly from rhyolitic magma.to make small implements and accessories. For example, Shirataki, Hokkaido (north island) is the largest place producing obsidian in Japan where Paleolithic people made arrowhead, knives and so on. Another example, Jade yielded in Itoigawa City, Japan Sea coast of central Japan, was made in the metamorphic rock about five hundred million years ago. Itoigawa area is only one place where jade is abundantly produced in Japan. Ancient people had been already collected and processed to ornaments although it is very hard and traded in wide area more than several thousand years ago. 2. Stone Heritages of Historical age: 2.1 Archaeological remains: In the Kofun (old mound) period (250 to 538 AD), stone burial chambers were used for old mounds to preserve against the putrefaction and to protect from the theft. For example, Ishibutai Kofun ("ishi" means "stone" and "butai" means "stage") in Nara old capital city, southwest Japan, is the largest known megalithic structure made of granite in Japan. 2.2 Stone walls of some typical castles Stones used is because of not only the rich reserves of rocks but also restriction of transportation. Osaka (second biggest city) castle, are composed of Cretaceous granite

  10. The cause of larger local magnitude (Mj) in western Japan

    NASA Astrophysics Data System (ADS)

    Kawamoto, H.; Furumura, T.

    2017-12-01

    The local magnitude of the Japan Meteorological Agency (JMA) scale (Mj) in Japan sometimes show a significant discrepancy between Mw. The Mj is calculated using the amplitude of the horizontal component of ground displacement recorded by seismometers with the natural period of T0=5 s using Katsumata et al. (2004). A typical example of such a discrepancy in estimating Mj was an overestimation of the 2000 Western Tottori earthquake (Mj=7.3, Mw=6.7; hereafter referred to as event T). In this study, we examined the discrepancy between Mj and Mw for recent large earthquakes occurring in Japan.We found that the most earthquakes with larger Mj (>Mw) occur in western Japan while the earthquakes in northern Japan show reasonable Mj (=Mw). To understand the cause of such larger Mj for western Japan earthquakes we examined the strong motion record from the K-NET and KiK-net network for the event T and other earthquakes for reference. The observed ground displacement record from the event T shows a distinctive Love wave packet in tangential motion with a dominant period of about T=5 s which propagates long distances without showing strong dispersions. On the other hand, the ground motions from the earthquakes in northeastern Japan do not have such surface wave packet, and attenuation of ground motion is significant. Therefore, the overestimation of the Mj for earthquakes in western Japan may be attributed to efficient generation and propagation properties of Love wave probably relating to the crustal structure of western Japan. To explain this, we then conducted a numerical simulation of seismic wave propagation using 3D sedimentary layer model (JIVSM; Koketsu et al., 2012) and the source model of the event T. The result demonstrated the efficient generation of Love wave from the shallow strike-slip source which propagates long distances in western Japan without significant dispersions. On the other hand, the generation of surface wave was not so efficient when using a

  11. Words of Tohkaku Wada: medical heritage in Japan.

    PubMed

    Matsumoto, M; Inoue, K; Kajii, E

    2001-02-01

    The origins of Japan's medical ideas, which are deeply rooted in its religion, culture and history, are not widely understood in medical societies of other countries. We have taken up the task of summarising this tradition here so that some insight can be gained into the unique issues that characterise the practice of medicine in Japan. We borrow from the sayings of Tohkaku Wada, a medical philosopher of late eighteenth-century Japan, for a look at Japanese medical tradition. Wada's medical thought was very much reflective of the Buddhism, Zen, and swordsmanship that informed eighteenth-century philosophy in Japan. His central concepts were "chu" and "sei", that is, complete and selfless dedication to the patient and the practice of medicine. This paper explores Wada's thought, explaining it mainly from the standpoint of Japanese traditional culture.

  12. Japan: Language Policy and Planning in Transition

    ERIC Educational Resources Information Center

    Gottlieb, Nanette

    2008-01-01

    This monograph discusses the language situation in Japan, with an emphasis on language planning and policy. Japan has long considered itself to be a monoethnic and therefore monolingual society, despite the existence of substantial old-comer ethnic minorities, and this--with the instrumental exception of English--has been reflected in its language…

  13. [Rabies contingency plan in Japan].

    PubMed

    Inoue, Satoshi

    2005-12-01

    In Japan, rabies has been culled out since 1957 thanks to the strong implementation of measures against rabies, such as vaccination of dogs, quarantine and control of wild dogs under the 'Rabies Prevention Law' enacted in 1950. Nevertheless one cannot deny the possibility of introduction of rabies into Japan in view of the recent increase in the international movements of people and animals. Should an outbreak of rabies be suspected now in Japan, the society would probably overreact due to a decreased awareness of risks and a lack of correct knowledge about this disease. Officials of the government and the municipalities, veterinarians and doctors should exchange correct information on rabies and on prevention control and raise their awareness, while providing also information to the public on a timely basis. Besides it is needless to say that it is important to set up a crisis management system allowing a quick and adequate response in case of an outbreak of rabies and to continue to implement appropriate prevention measures in normal times.

  14. Testing the Nuclear Will of Japan

    DTIC Science & Technology

    2007-12-01

    particularly the United States. This was significant because a soured economic relationship would undoubtedly affect the U.S.-Japan security...around the world, has sometimes soured its image as a serious international player.136 This is because many of the world’s great powers have extended...for International Exchange, 2005. Beer , Lawrence W. “Japan Turning the Corner.” Asian Survey 11, no. 1 (January 1971): 74 – 85. Bueno de Mesquita

  15. Toward freedom from cancer pain in Japan.

    PubMed

    Otsuka, Kuniko; Yasuhara, Hajime

    2007-01-01

    Life expectancy in Japan is highest in the world. Cancer is the leading cause of mortality in Japan, accounting for about 30 percent of all deaths. Many Japanese cancer patients experience severe pain although they and their families hope to be pain free at the end of their lives. Toward that end, the consumption of morphine in Japan has increased markedly since 1989. The amount of morphine hydrochloride and morphine sulfate consumed in 2001 was 6.1 times that used in Japan in 1989. However, the amount of morphine consumed in Japan is still less than in other developed nations, and was only one-sixth of the amount used in Australia in 2001. As a result, many Japanese cancer patients experience potentially manageable cancer pain, largely because the amount of the drug used by doctors is insufficient for pain control. An increasing number of Japanese doctors now understand that their patients' quality of life is most important in end-of-life care and how to use the three step analgesic ladder of the World Health Organization (WHO). However, other doctors do not understand these issues sufficiently causing some patients to die without good pain control. Both the general population and some medical professionals misunderstand and have prejudice against the use of morphine. Patients often do not participate in decision making about medical treatment because of remaining paternalism in the relationship between Japanese doctors and patients. Thus, cancer pain management in Japan is not as effective as it can be and not all Japanese cancer patients receive appropriate management for their cancer pain. To improve outcomes for Japanese patients, it is necessary for health professional and social work students and practicing professionals to receive contemporary education including an introduction to palliative care and ethics.

  16. Regional and transported aerosols during DRAGON-Japan experiment

    NASA Astrophysics Data System (ADS)

    Sano, I.; Holben, B. N.; Mukai, S.; Nakata, M.; Nakaguchi, Y.; Sugimoto, N.; Hatakeyama, S.; Nishizawa, T.; Takamura, T.; Takemura, T.; Yonemitsu, M.; Fujito, T.; Schafer, J.; Eck, T. F.; Sorokin, M.; Kenny, P.; Goto, M.; Hiraki, T.; Iguchi, N.; Kouzai, K.; KUJI, M.; Muramatsu, K.; Okada, Y.; Sadanaga, Y.; Tohno, S.; Toyazaki, Y.; Yamamoto, K.

    2013-12-01

    Aerosol properties over Japan have been monitored by AERONET sun / sky photometers since 2000. These measurements provides us with long term information of local aerosols, which are influenced by transported aerosols, such as Asian dusts or anthropogenic pollutants due to rapid increasing of energy consumption in Asian countries. A new aerosol monitoring experiment, Distributed Regional Aerosol Gridded Observation Networks (DRAGON) - Japan is operated in spring of 2012. The main instrument of DRAGON network is AERONET sun/sky radiometers. Some of them are sparsely set along the Japanese coast and some others make a dense network in Osaka, which is the second-largest city in Japan and famous for manufacturing town. Several 2ch NIES-LIDAR systems are also co-located with AERONET instrument to monitor Asian dusts throughout the campaign. The objects of Dragon-Japan are to characterize local aerosols as well as transported ones from the continent of China, and to acquire the detailed aerosol information for validating satellite data with high resolved spatial scale. This work presents the comprehensive results of aerosol properties with respect to regional- and/or transported- scale during DRAGON-Japan experiments.

  17. Post-flowering nitrate uptake in wheat is controlled by N status at flowering, with a putative major role of root nitrate transporter NRT2.1.

    PubMed

    Taulemesse, François; Le Gouis, Jacques; Gouache, David; Gibon, Yves; Allard, Vincent

    2015-01-01

    In bread wheat (Triticum aestivum L.), the simultaneous improvement of both yield and grain protein is difficult because of the strong negative relationship between these two traits. However, some genotypes deviate positively from this relationship and this has been linked to their ability to take up nitrogen (N) during the post-flowering period, regardless of their N status at flowering. The physiological and genetic determinants of post-flowering N uptake relating to N satiety are poorly understood. This study uses semi-hydroponic culture of cv. Récital under controlled conditions to explore these controls. The first objective was to record the effects of contrasting N status at flowering on post-flowering nitrate (NO₃⁻) uptake under non-limiting NO₃⁻ conditions, while following the expression of key genes involved in NO₃⁻ uptake and assimilation. We found that post-flowering NO₃⁻ uptake was strongly influenced by plant N status at flowering during the first 300-400 degree-days after flowering, overlapping with a probable regulation of nitrate uptake exerted by N demand for growth. The uptake of NO₃⁻ correlated well with the expression of the gene TaNRT2.1, coding for a root NO₃⁻ transporter, which seems to play a major role in post-flowering NO₃⁻ uptake. These results provide a useful knowledge base for future investigation of genetic variability in post-flowering N uptake and may lead to concomitant gains in both grain yield and grain protein in wheat.

  18. The educational system in Japan

    NASA Technical Reports Server (NTRS)

    Spearman, M. L.

    1986-01-01

    The rapid economic growth of Japan since World War II has resulted in Japan becoming a reference point for developing nations and the West. This remarkable growth results from a combination of factors, one of which has been unyielding attention to education in order to cultivate the human talent necessary to provide the productivity for economic growth. The Japanese education system emphasizes quality of instruction and rewards hard work. Some of the principles of the system are outlined together with a summary of the content of the curriculum, the quantity and quality of instruction, and the influence of culture and environment.

  19. The UK-Japan Young Scientist Workshop Programme...

    ERIC Educational Resources Information Center

    Albone, Eric; Okano, Toru

    2012-01-01

    The authors have been running UK-Japan Young Scientist Workshops at universities in Britain and Japan since 2001: for the past three years in England with Cambridge University and, last year, also with Kyoto University and Kyoto University of Education. For many years they have worked jointly with colleagues in a group of Super Science High…

  20. View from... JSAP spring meeting 2007: Inside Japan

    NASA Astrophysics Data System (ADS)

    Won, Rachel; Graydon, Oliver

    2007-06-01

    Photonics research in Japan is thriving and there is no better place to hear the latest news firsthand than the meetings of the Japan Society of Applied Physics. Nature Photonics decided to pay the 54th Spring Meeting a visit.

  1. 76 FR 8774 - Granular Polytetrafluoroethylene Resin From Japan

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-15

    ... INTERNATIONAL TRADE COMMISSION [Investigation No. 731-TA-386 (Third Review)] Granular Polytetrafluoroethylene Resin From Japan AGENCY: United States International Trade Commission. ACTION: Termination of five... revocation of the antidumping duty order on granular polytetrafluoroethylene resin from Japan would be likely...

  2. U.S. hardwood exports, hardwood exports to Japan, hardwood resource situation, and the future of U.S. exports to Japan

    Treesearch

    Philip A. Araman

    1989-01-01

    This paper looks at some basic information about total U.S. hardwood exports and products as well as hardwood exports to Japan. It also discusses the U.S. hardwood resource situation and how we can best use the resource base to suppy Japanâs needs.

  3. A brief history of the Japan Society for Cell Biology.

    PubMed

    Tashiro, Y; Okigaki, T

    2001-02-01

    The Japan Society for Cell Biology (JSCB) was first founded in 1950 as the Japan Society for Cellular Chemistry under the vigorous leadership of Seizo Katsunuma, in collaboration with Shigeyasu Amano and Satimaru Seno. The Society was provisionally named as above simply because cell biology had not yet been coined at that time in Japan, although in prospect and reality the Society was in fact for the purpose of pursuing cell biology. Later in 1964, the Society was properly renamed as the Japan Society for Cell Biology. After this renaming, the JSCB made great efforts to adapt itself to the rapid progress being made in cell biology. For this purpose the Society's constitution was created in 1966 and revised in 1969. According to the revised constitution, the President, Executive Committee and Councils were to be determined by ballot vote. The style of the annual meetings was gradually modified to incorporate general oral and poster presentations in addition to Symposia (1969-1974). The publication of annual periodicals in Japanese called Symposia of the Japan Society for Cellular Chemistry (1951-1967) and later Symposia of the Japan Society for Cell Biology (1968-1974) was replaced by a new international journal called Cell Structure and Function initiated in 1975. This reformation made it possible for the Society to participate in the Science Council of Japan in 1975 and finally in 1993 to acquire its own study section of Cell Biology with grants-in-aid from the Ministry of Education and Science, Japan. The JSCB hosted the 3rd International Congress on Cell Biology (ICCB) in 1984 and the 3rd Asian-Pacific Organization for Cell Biology (APOCB) Congress in 1998, thus contributing to the international advancement of cell biology. Now the membership of JSCB stands at approximately 1,800 and the number of presentations per meeting is 300 to 400 annually. Although a good number of interesting and important findings in cell biology have been reported from Japan, the

  4. Using Parse's humanbecoming theory in Japan.

    PubMed

    Tanaka, Junko; Katsuno, Towako; Takahashi, Teruko

    2012-01-01

    In this paper the authors discuss the use of Parse's humanbecoming theory in Japan. Elements of the theory are used in the nursing approach to an 88 year-old Japanese man who had complications following surgery. Process recordings of the dialogues between the patient, the patient's wife, and the nurse were made and considered in light of the three methodologies of Parse's theory; illuminating meaning, synchronizing rhythms, and mobilizing transcendence. The theory is seen as useful in Japan.

  5. Country Profiles. Japan.

    ERIC Educational Resources Information Center

    Muramatsu, Minoru

    This occasional paper on Japan is one of a series setting forth the nature, scope, and accomplishments of population activities in specified countries. Here, an overview is given of population characteristics and growth patterns, the relationship of population growth to socioeconomic development, and the history of population concerns and…

  6. What is nuclear power in Japan?

    NASA Astrophysics Data System (ADS)

    Suzuki, Toshikazu

    2011-03-01

    The aggressive use of such non-fossil energy as the atomic energy with high power density and energy production efficiency is an indispensable choice aiming at the low-carbon society. There is a trial calculation that the carbon dioxide emission of 40000 ton can be suppressed by nuclear power generation by one ton of uranium. The basis of nuclear research after the Second World War in Japan was established by the researchers learnt in Argonne National Laboratory. In 2010, NPPs under operation are 54 units and the total electric generating power is 48.85GW. The amount of nuclear power generation per person of the people is 0.38kW in Japan, and it is near 0.34kW of the United States. However, the TMI accident and the Chernobyl disaster should have greatly stagnated the nuclear industry of Japan although it is not more serious than the United States. A lot of Japanese unconsciously associate a nuclear accident with the atomic bomb. According to the investigation which Science and Technology Agency carried out to the specialist in 1999, ``What will be the field where talent should be emphatically sent in the future?'' the rank of nuclear technology was the lowest in 32 fields. The influence of the nuclear industry stagnation was remarkable in the education. The subject related to the atomic energy of a university existed 19 in 1985 that was the previous year of the Chernobyl disaster decreased to 7 in 2003. In such a situation, we have to rely on the atomic energy because Japan depends for 96% of energy resources on import. The development of the fuel reprocessing and the fast breeder reactor has been continued in spite of a heavy failure. That is the only means left behind for Japan to be released from both fossil fuel and carbon dioxide.

  7. 76 FR 8773 - Superalloy Degassed Chromium From Japan

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-15

    ... INTERNATIONAL TRADE COMMISSION [Investigation No. 731-TA-1090 (Review)] Superalloy Degassed Chromium From Japan AGENCY: United States International Trade Commission. ACTION: Termination of five-year... revocation of the antidumping duty order on superalloy degassed chromium from Japan would be likely to lead...

  8. Neuropsychology in Japan: history, current challenges, and future prospects.

    PubMed

    Sakamoto, Maiko

    2016-11-01

    The purpose of this special issue was to describe the cross-cultural differences in neuropsychology throughout the world. The current state of neuropsychology in Japan is discussed in this manuscript. Information on six topics, including (1) the history of Japanese neuropsychology, (2) licensure system, (3) job opportunities, (4) neuropsychological clinical services, (5) neuropsychological tests, and (6) neuropsychological research, was gathered via literature searches, official organization websites, and personal communication with clinical psychologists and other professionals in Japan. Neuropsychology reached Japan from the west in the late 1800s, a period of rapid political and social modernization. Professional associations were founded in the 1960s and 1970s and continued to grow. The need for neuropsychological assessment in Japan is growing; however, credential requirements for neuropsychologists have not yet been established. To practice clinical psychology in Japan, one must obtain a Master's degree and pass a licensure examination that is administered by a private professional foundation. Clinical psychologists often conduct neuropsychological tests; however, they have little training in neuropsychological assessment. While many western neuropsychological tests have been translated into Japanese and are used in clinical settings, the majority of translated tests have not been standardized and their psychometric properties remain poorly understood. Standardization and development of normative data in Japan is warranted. Given that needs for neuropsychological services are increasing, it is essential for clinical psychologists in Japan to improve their skills in neuropsychological evaluations. Japanese graduate schools must work to establish neuropsychology programs to educate and train clinical neuropsychologists.

  9. Computerizing medical records in Japan.

    PubMed

    Yasunaga, Hideo; Imamura, Tomoaki; Yamaki, Shintaro; Endo, Hiroyoshi

    2008-10-01

    The present study reports the current status of computerizing medical records in Japan. In 2001, the Ministry of Health, Labour and Welfare formulated the Grand Design for the Development of Information Systems in the Healthcare and Medical Fields. The Grand Design stated a numerical target for "spreading the use of electronic medical records (EMR) in at least 60% of Japan's hospitals with 400 or more beds by 2006." The objective of this study was to examine the extent to which EMR and order entry systems (OES) have been adopted as of February 2007 and to evaluate the Japanese government's policy regarding the computerization of medical records. We conducted a postal survey targeting medical institutions throughout Japan. In February 2007, we mailed self-administered questionnaires to all 1574 hospitals with 300 or more beds, and to a random selection of 1000 hospitals with less than 300 beds in addition to 4000 clinics. Responses were received from 812 (51.6%), 504 (50.5%), and 1769 (44.8%), respectively. We asked questions concerning: (i) the extent to which EMR and OES had been introduced; (ii) the reasons why certain institutions had not introduced EMR and (iii) the subjective evaluation of the efficacy and cost-effectiveness of EMR. The percentage of institutions that had introduced EMR as of February 2007 was 10.0% for hospitals and 10.1% for clinics. Even the percentage for hospitals with 400 or more beds was just 31.2%, illustrating that the government's target had not been reached. The most common reason given for not introducing EMR was: "The cost is high" which was observed in 82.0% of hospitals. It was considered that the introduction of EMR could improve 'inter-hospital networks', and 'time efficiency for physicians' by around 45% and 25% of hospitals, respectively. Healthcare information computerization in Japan is behind schedule because the introductory costs are high. For the computerization of healthcare information to be further promoted, prices

  10. JTEC panel report on advanced composites in Japan

    NASA Technical Reports Server (NTRS)

    Diefendorf, R. J.; Grisaffe, S. J.; Hillig, W. B.; Perepezko, J. H.; Pipes, R. B.; Sheehan, J. E.

    1991-01-01

    The JTEC Panel on Advanced Composites visited Japan and surveyed the status and future directions of Japanese high performance ceramic and carbon fibers and their composites in metal, intermetallic, ceramic and carbon matrices. The panel's interests included not only what composite systems were chosen, but also how these systems were developed. A strong carbon and fiber industry makes Japan the leader in carbon fiber technology. Japan has initiated an oxidation resistant carbon/carbon composite program. The goals for this program are ambitious, and it is just starting, but its progress should be closely monitored in the United States.

  11. Frontiers Of Education: Japan As ``Global Model'' Or ``Nation At Risk''?

    NASA Astrophysics Data System (ADS)

    Willis, David Blake; Yamamura, Satoshi; Rappleye, Jeremy

    2008-07-01

    The Japanese educational system is undergoing extensive change, affecting all stages from pre-school programmes to higher education. As Japan has moved from a nation at the top to "A Nation at Risk," certain dichotomies have been highlighted. Viewing Japan as either educational super-power or educational tragedy, depending on the era of research or background of the researchers, has been especially provocative for educators and policy-makers. At the same time, the controversies in America surrounding the report A Nation at Risk (National Commission on Excellence in Education) are well known, a major impetus for the report of course being Japan. Central to the question of whether Japan is best understood as a Global Model or A Nation at Risk are themes of cross-national attraction and educational transfer. What can the world learn from Japan? What does Japan need to learn from the world? The answers to these questions have particular significance for Japanese higher education, which we take up as a case study here, with its urgent task to innovate in the face of a steep demographic downward trend. For those in Japan who feel that Japanese education is in a dismal state, what are the origins of this serious decline? For observers in other national contexts who envisage Japan as a model, how do the calls to ‹learn from Japan' reflect genuine attempts to improve practice at home? Or are they simply rhetorical tools in support of domestic political projects?

  12. Effects of market liberalisation on smoking in Japan

    PubMed Central

    Honjo, K.; Kawachi, I.

    2000-01-01

    OBJECTIVE—To document the effect of the liberalisation of the Japanese tobacco market on Japanese smoking rates and on Japanese tobacco industry practices.
DATA SOURCE—Asahi Shimbun (major daily newspaper) from 1980 to 1996.
STUDY SELECTION—Review of media coverage on the effects of market liberalisation following the imposition of the USA's section 301 trade sanction.
DATA SYNTHESIS—The opening of Japan's tobacco market to foreign cigarette companies stalled a decline in smoking prevalence. Smoking rates among young women increased significantly, and also appear to be on the rise among adolescents. Aggressive marketing and promotional activities by US and Japanese tobacco companies in response to trade liberalisation appear responsible for these adverse trends. Steep increases in sales through vending machines were also possible contributors to the rising smoking prevalence among adolescents. On the positive side, market liberalisation indirectly promoted smoking control efforts in Japan, by causing an anti-smoking movement to coalesce.
CONCLUSION—Market liberalisation in Japan played a significant role in increasing smoking prevalence among young women and adolescents while helping to transform the issue of smoking in Japan from a matter of individual choice to a public health problem.


Keywords: Japan; market liberalisation PMID:10841856

  13. U.S.-Japan Seminar on Dielectric and Piezoelectric Ceramics Held in Kyoto, Japan on 11-14 December 1990

    DTIC Science & Technology

    1991-10-01

    Hydrothermal Electrochemical Method" Y. Sakabe, Y. Hamaji, M. Hayashi . Y. Ogino, N. Ishizawa* and M. Yoshimura* (Murata Mfg. Co., Ltd., *Research Laboratory of...Koya Hayashi Research and Development Division Research and Development Sakai Chemical Industry Co., Ltd. Shoei Chemical Inc. 5-1 Ebisujima, Sakai...Shinagawa 14-18 Takatsuji-cho, Mizuho-ku Tokyo 141, Japan Nagoya 467-91, Japan Akira Nagai Tomeji Ohno Odawara Research Center TOKIN Corporation

  14. Cancer incidence and incidence rates in Japan in 2008: a study of 25 population-based cancer registries for the Monitoring of Cancer Incidence in Japan (MCIJ) project.

    PubMed

    Matsuda, Ayako; Matsuda, Tomohiro; Shibata, Akiko; Katanoda, Kota; Sobue, Tomotaka; Nishimoto, Hiroshi

    2014-04-01

    The Japan Cancer Surveillance Research Group aimed to estimate the cancer incidence in Japan in 2008 based on data collected from 25 of 34 population-based cancer registries, as part of the Monitoring of Cancer Incidence in Japan project. The incidence in Japan for 2008 was estimated to be 749 767 (C00-C96). Stomach cancer and breast cancer were the leading types of cancer in males and females, respectively.

  15. NASA Satellite Image of Japan Captured March 11, 2011

    NASA Image and Video Library

    2017-12-08

    NASA's Aqua satellite passed over Japan one hour and 41 minutes before the quake hit. At the time Aqua passed overhead, the Moderate Resolution Imaging Spectroradiometer (MODIS) instrument captured a visible of Japan covered by clouds. The image was taken at 0405 UTC on March 11 (1:05 p.m. local time Japan /11:05 p.m. EST March 10). The quake hit at 2:46 p.m. local time/Japan. Satellite: Aqua Credit: NASA/GSFC/Aqua NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Join us on Facebook

  16. AutoNR: an automated system that measures ECAP thresholds with the Nucleus Freedom cochlear implant via machine intelligence.

    PubMed

    Botros, Andrew; van Dijk, Bas; Killian, Matthijs

    2007-05-01

    AutoNRT is an automated system that measures electrically evoked compound action potential (ECAP) thresholds from the auditory nerve with the Nucleus Freedom cochlear implant. ECAP thresholds along the electrode array are useful in objectively fitting cochlear implant systems for individual use. This paper provides the first detailed description of the AutoNRT algorithm and its expert systems, and reports the clinical success of AutoNRT to date. AutoNRT determines thresholds by visual detection, using two decision tree expert systems that automatically recognise ECAPs. The expert systems are guided by a dataset of 5393 neural response measurements. The algorithm approaches threshold from lower stimulus levels, ensuring recipient safety during postoperative measurements. Intraoperative measurements use the same algorithm but proceed faster by beginning at stimulus levels much closer to threshold. When searching for ECAPs, AutoNRT uses a highly specific expert system (specificity of 99% during training, 96% during testing; sensitivity of 91% during training, 89% during testing). Once ECAPs are established, AutoNRT uses an unbiased expert system to determine an accurate threshold. Throughout the execution of the algorithm, recording parameters (such as implant amplifier gain) are automatically optimised when needed. In a study that included 29 intraoperative and 29 postoperative subjects (a total of 418 electrodes), AutoNRT determined a threshold in 93% of cases where a human expert also determined a threshold. When compared to the median threshold of multiple human observers on 77 randomly selected electrodes, AutoNRT performed as accurately as the 'average' clinician. AutoNRT has demonstrated a high success rate and a level of performance that is comparable with human experts. It has been used in many clinics worldwide throughout the clinical trial and commercial launch of Nucleus Custom Sound Suite, significantly streamlining the clinical procedures associated with

  17. Insights into software development in Japan

    NASA Technical Reports Server (NTRS)

    Duvall, Lorraine M.

    1992-01-01

    The interdependence of the U.S.-Japanese economies makes it imperative that we in the United States understand how business and technology developments take place in Japan. We can gain insight into these developments in software engineering by studying the context in which Japanese software is developed, the practices that are used, the problems encountered, the setting surrounding these problems, and the resolution of these problems. Context includes the technological and sociological characteristics of the software development environment, the software processes applied, personnel involved in the development process, and the corporate and social culture surrounding the development. Presented in this paper is a summary of results of a study that addresses these issues. Data for this study was collected during a three month visit to Japan where the author interviewed 20 software managers representing nine companies involved in developing software in Japan. These data are compared to similar data from the United States in which 12 managers from five companies were interviewed.

  18. [Establishment of anatomical terminology in Japan].

    PubMed

    Shimada, Kazuyuki

    2008-12-01

    The history of anatomical terminology in Japan began with the publication of Waran Naikei Ihan-teimŏ in 1805 and Chŏtei Kaitai Shinsho in 1826. Although the establishment of Japanese anatomical terminology became necessary during the Meiji era when many western anatomy books imported into Janan were translated, such terminology was not unified during this period and varied among translators. In 1871, Tsukumo Ono's Kaibŏgaku Gosen was published by the Ministry of Education. Although this book is considered to be the first anatomical glossary terms in Japan, its contents were incomplete. Overseas, the German Anatomical Society established a unified anatomical terminology in 1895 called the Basle Nomina Anatomica (B.N.A.). Based on this development, Kaibŏgaku Meishŭ which follows the BNA, by Buntarŏ Suzuki was published in 1905. With the subsequent establishment in 1935 of Jena Nomina Anatomica (J.N.A.), the unification of anatomical terminology was also accelerated in Japan, leading to the further development of terminology.

  19. The Issue of Diversity and Multiculturalism in Japan

    ERIC Educational Resources Information Center

    Qi, Jie; Zhang, Sheng Ping

    2008-01-01

    The purpose of this paper is to problematize that which has been taken for granted about the notion of multiculturalism in Japan. Multiculturalism is a "hot" issue in Japan. As the Japanese government started to promote "internationalization" since 1980s, slogans such as "international exchange," "cultural…

  20. "I'm Not Going to Be in Japan Forever": How Filipina Immigrant Youth in Japan Construct the Meaning of Home

    ERIC Educational Resources Information Center

    Tokunaga, Tomoko

    2011-01-01

    This article, based on an ethnographic study of five Filipino-born daughters of Filipina migrant workers in Japan, discusses how these young women construct understandings of home as they navigate the borderlands between the Philippines, Japan and the US. The study reveals the ways in which these young women negotiate the possibilities and…

  1. Japan Country Analysis Brief

    EIA Publications

    2017-01-01

    Japan is the world's largest liquefied natural gas importer and ranks in the top four countries for the highest coal imports, net imports of petroleum and other liquids, and consumption of crude oil and petroleum products.

  2. Teaching Unit: Japan.

    ERIC Educational Resources Information Center

    Evans, Dina

    The cultural diversity of Japan can provide a rewarding learning experience for children of all grade levels. This teaching unit includes resources and ideas for the study of Japanese society, art, folklore, and poetry. Included among the instructional objectives are: (1) children will compare U.S. lifestyles with Japanese lifestyles by reading…

  3. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Haddow, Andrew D., E-mail: adhaddow@gmail.com; Guzman, Hilda; Popov, Vsevolod L.

    We report here the first evidence of vertical transmission of Aedes flavivirus (AEFV) and its first isolation in the Western Hemisphere. AEFV strain SPFLD-MO-2011-MP6 was isolated in C6/36 cells from a pool of male Aedes albopictus mosquitoes that were reared to adults from larvae collected in southwest Missouri, USA, in 2011. Electron micrographs of the virus showed virions of approximately 45 nm in diameter with morphological characteristics associated with flaviviruses. The genomic sequence demonstrated that AEFV-SPFLD-MO-2011-MP6 shares a high degree of nucleotide and amino acid sequence identity with the AEFV Narita-21 strain, isolated in Japan in 2003. Intracerebral inoculation ofmore » newborn mice with the virus failed to produce observable illness or death and the virus did not replicate in vertebrate cells, consistent with a lack of vertebrate host range. - Highlights: ► The first report of Aedes flavivirus (AEFV) in the Western Hemisphere. ► The first evidence of vertical transmission of AEFV in mosquitoes. ► The first electron micrograph of AEFV. ► The first attempt to infect animals with AEFV.« less

  4. De novo malignancy after pancreas transplantation in Japan.

    PubMed

    Tomimaru, Y; Ito, T; Marubashi, S; Kawamoto, K; Tomokuni, A; Asaoka, T; Wada, H; Eguchi, H; Mori, M; Doki, Y; Nagano, H

    2015-04-01

    Long-term immunosuppression is associated with an increased risk of cancer. Especially, the immunosuppression in pancreas transplantation is more intensive than that in other organ transplantation because of its strong immunogenicity. Therefore, it suggests that the risk of post-transplant de novo malignancy might increase in pancreas transplantation. However, there have been few studies of de novo malignancy after pancreas transplantation. The aim of this study was to analyze the incidence of de novo malignancy after pancreas transplantation in Japan. Post-transplant patients with de novo malignancy were surveyed and characterized in Japan. Among 107 cases receiving pancreas transplantation in Japan between 2001 and 2010, de novo malignancy developed in 9 cases (8.4%): post-transplant lymphoproliferative disorders in 6 cases, colon cancer in 1 case, renal cancer in 1 case, and brain tumor in 1 case. We clarified the incidence of de novo malignancy after pancreas transplantation in Japan. Copyright © 2015 Elsevier Inc. All rights reserved.

  5. Rickettsioses in Japan and the far East.

    PubMed

    Mahara, Fumihiko

    2006-10-01

    Three rickettsial diseases are known to exist in Japan currently: Japanese spotted fever (JSF), Tsutsugamushi disease (TD; scrub typhus), and Q fever. Since April 1999, the system for infection control and prevention in Japan has changed drastically. JSF, Q fever, and TD, as emerging infectious diseases, are designated as national notifiable diseases.The geographic distribution of JSF patients is along the coast of central and southwestern Japan, whereas TD and Q fever occur almost all over the country. The number of JSF patients reported was 216 cases during 1984-1998 and 268 cases, under the revised law, in 1999-2004. About 300-1000 cases of TD occur every year, and 7-46 cases of Q fever in 1999-2004. The number of cases of JSF and its endemic area are gradually increasing. There was only one fatality due to JSF until 2003, whereas two patients died of JSF in 2004, so JSF is still a life-threatening disease in Japan. Treatment of fulminant JSF consists of prompt administration of a combination of tetracycline and quinolone. Recent tick surveys revealed that the most probable vectors of JSF are Haemophysalis flava and Haemophysalis hystericis. In addition to R. japonica, two serotypes or species of spotted fever group rickettsiae have been isolated from ticks in Japan; one is closely related to R. helvetica and the other is a new genotype of unknown genotype AT, which is closely related to a Slovakian genotype. These serotypes are of uncertain clinical significance. Epidemiology of rickettsioses in the Far East is mentioned briefly.

  6. Toward a tobacco-free society in Japan.

    PubMed

    Tokunaga, H

    2001-08-01

    Tobacco is one of the major preventable causes of death and disability. This is widely known in both Japan and the USA, and although the smoking rate in the USA is decreasing, that in Japan remains high. The tobacco histories of these two countries, which provide the background to this difference, are herein compared. The antismoking movement is becoming more vociferous in both countries. Publicity regarding of the dangers of smoking, warning signs on tobacco packages, the introduction of antismoking devices, a ban on commercials for tobacco-related products on TV and the radio, no-smoking seats on airplanes, and litigation against the tobacco industry have all been introduced. However, major differences remain between these two countries. The tobacco industry in the USA has been a private company since it was first established. Courts have ordered the tobacco industry to pay compensation for damage to health resulting from tobacco. Smoking is strictly restricted inside buildings. Advertisements for nicotine gum and nicotine patches and reports on the dangers of smoking are regularly broadcast. In the case of Japan, the government at first nationalized the tobacco industry, and then made it a private company, although the government still holds two-thirds of its stock. Moreover, it established the Tobacco Business Law to support the company. The main purpose of antismoking campaigns in Japan is a partial ban on smoking. On the basis of these differences between the two countries regarding the history of tobacco, the antismoking movement in Japan has yet to choose which path to take.

  7. Q fever in Japan: an update review.

    PubMed

    Porter, Sarah Rebecca; Czaplicki, Guy; Mainil, Jacques; Horii, Yoichiro; Misawa, Naoaki; Saegerman, Claude

    2011-05-05

    As neglected zoonosis for many years, Q fever is now ubiquitous in Japan. Similarly to elsewhere in the world, domestic animals are considered to be important reservoirs of the causal agent, Coxiella burnetii, a resistant intracellular bacterium. Infected animals shed bacteria in milk, feces, urine, vaginal mucous and birth products. Inhalation of bacteria present in the environment is the main route of animal and human infection. Shedding of C. burnetii in milk by domestic ruminants has a very limited impact as raw milk is seldom ingested by the Japanese population. The clinical expression of Q fever in Japan is similar to its clinical expression elsewhere. However clinical cases in children are more frequently reported in this country. Moreover, C. burnetii is specified as one of the causative organisms of atypical pneumonia in the Japanese Respiratory Society Guideline for the management of community-acquired pneumonia. In Japan, C. burnetii isolates are associated with acute illness and are mainly of moderate to low virulence. Cats are considered a significant source of C. burnetii responsible for human outbreaks in association with the presence of infected parturient cats. Since its recognition as a reportable disease in 1999, 7-46 clinical cases of Q fever have been reported by year. The epidemiology of Q fever in Japan remains to be elucidated and the exact modes of transmission are still unproven. Important further research is necessary to improve knowledge of the disease itself, the endogenous hosts and reservoirs, and the epidemiological cycle of coxiellosis in Japan. Copyright © 2010 Elsevier B.V. All rights reserved.

  8. Distant Mt. Fuji, Island of Honshu Japan

    NASA Image and Video Library

    1992-11-01

    This distant view of Mt. Fuji, on the main home island of Honshu, Japan (34.0N, 139.0E) was taken from about 450 miles to the south. Evan at that great distance, the majestic and inspiring Mt. Fuji is still plainly visible and easily recognized as a world renowned symbol of Japan. The snow capped extinct volcano lies just a few miles south of Tokyo.

  9. [C.P. Thunberg and his voyage to Japan (4). Mercury water therapy for syphilis introduced into Japan by Thunberg].

    PubMed

    Takahashi, F

    1994-01-01

    During his 16-month stay in Japan from August 1775 to December 1776, Thunberg taught mercury water therapy to Japanese medical doctors and interpreters in order to help them treat syphilis, which was prevalent in Japan at that time. Kohgyu Yoshio, a Japanese-Dutch interpreter who was taught this therapy by Thunberg, recorded Thunberg's teaching in his "Kohmoh Hijiki." According to this book, the mercury water therapy that Thunberg introduced to Japan had been tested successfully by van Swieten, a Dutch doctor, about 20 years previously in Europe and used corrosive sublimate (mercuric chloride), the active ingredient, dissolved in distilled water with honey. The formula is described, in measurement units used in Europe at that time, in a letter addressed by van Swieten to a doctor in Rotterdam in 1755. The formula recorded in "Kohmoh Hijiki" in measurement units used in Japan at that time gives a content of the active ingredient equivalent to that mentioned in van Swieten's letter. This fact indicates that van Swieten's formula introduced by Thunberg was correctly accepted by Japanese doctors and interpreters, who had acquired basic medical knowledge since the publication of "Kaitai Shinsho" in 1774.

  10. Nonword Repetition and Language Development in 4-Year-Old Children with and without a History of Early Language Delay

    ERIC Educational Resources Information Center

    Thal, Donna J.; Miller, Scott; Carlson, Janna; Vega, Martha Moreno

    2005-01-01

    Purpose: This study examined the usefulness of the Nonword Repetition Test (NRT; C. Dollaghan & T. F. Campbell, 1998) with 4-year-old children and the relationship among the NRT, language, and other aspects of mental processing. Method: The NRT was administered to 64 children at 4 years of age; 44 had a history of typical language development…

  11. Safety of nicotine replacement therapy in critically ill smokers: a retrospective cohort study.

    PubMed

    Kerr, A; McVey, J T; Wood, A M; Van Haren, Fmp

    2016-11-01

    Nicotine replacement therapy (NRT) is a common first-line treatment to prevent nicotine withdrawal in smokers. However, available literature reports conflicting results regarding its efficacy and safety in critically ill patients. The objective of this study was to evaluate the relationship between NRT in smokers in the intensive care unit (ICU) and outcomes. This case-control study was conducted in a university-affiliated tertiary hospital ICU. Over a period of five years, 126 active smokers who received transdermal NRT were matched to 126 active smokers who did not receive NRT. The groups were case-matched for sex, age and Acute Physiology and Chronic Health Evaluation II (APACHE II) score. The primary outcome was administration of antipsychotic medication. Secondary outcomes included use of physical restraints, 30-day mortality, and ventilation requirements. Antipsychotic medication was prescribed in 43 (34.1%) patients who received NRT compared to 14 (11.1%) in controls ( P <0.01). Physical restraints were used in 37 (29.4%) patients who received NRT, compared to 12 (9.5%) of controls ( P <0.01). The 30-day mortality and number of patients intubated was not statistically different between groups. Average length of intubation time was greater in the NRT group (2.56 days; standard deviation 4.16) compared to the control group (1.44 days; standard deviation 2.68) ( P =0.012). The use of NRT to prevent nicotine withdrawal in ICU patients is associated with increased use of antipsychotic medication and physical restraint, and with prolonged mechanical ventilation.

  12. Motivating smokers at outdoor public smoking hotspots to have a quit attempt with a nicotine replacement therapy sample: study protocol for a randomized controlled trial.

    PubMed

    Cheung, Yee Tak Derek; Leung, Jessica Pui Kei; Cheung, Chelsia Ka Ching; Li, William Ho Cheung; Wang, Man Ping; Lam, Tai Hing

    2016-07-26

    About half of the daily smokers in Hong Kong have never tried and have no intention to quit smoking. More than one-third (37.9 %) of daily smokers have attempted to quit but failed. Nicotine replacement therapy (NRT) is a safe and effective pharmacotherapy to increase abstinence by reducing withdrawal symptoms during the early stage of smoking abstinence. However, the prevalence of NRT use in Hong Kong is lower than in most developed countries. The proposed study aims to assess the effectiveness of providing free NRT samples to smokers on increasing quit attempts and the quit rate. Trained university undergraduate students as ambassadors will invite smokers at outdoor public smoking hotspots to participate in the randomized controlled trial, in which eligible smokers will be randomized to receive a 1-week free NRT sample and medication counselling (intervention) or advice to purchase NRT on their own (control). The primary outcome is self-reported quit attempts (no smoking for at least 24 hours) in the past 30 days at 1-month and 3-month telephone follow-up. The findings will inform the effectiveness of delivering free NRT samples at outdoor public smoking hotspots to increase quit attempts and abstinence. The study will also provide information on smokers' adherence to the NRT sample, side effects and safety issues related to the usage. This will improve the design of a large trial to test the effect of the NRT sample. ClinicalTrials.gov NCT02491086 . Registered on 7 July 2015.

  13. Space communications in Japan

    NASA Astrophysics Data System (ADS)

    Mori, T.

    This paper outlines some of the planned satellite comunication projects in Japan over the next 5-7 years. In addition, Japanese space development policies are set out along with a historic review of the development of artificial satellites.

  14. 2016 Guidelines for the management of thyroid storm from The Japan Thyroid Association and Japan Endocrine Society (First edition).

    PubMed

    Satoh, Tetsurou; Isozaki, Osamu; Suzuki, Atsushi; Wakino, Shu; Iburi, Tadao; Tsuboi, Kumiko; Kanamoto, Naotetsu; Otani, Hajime; Furukawa, Yasushi; Teramukai, Satoshi; Akamizu, Takashi

    2016-12-30

    Thyroid storm is an endocrine emergency which is characterized by multiple organ failure due to severe thyrotoxicosis, often associated with triggering illnesses. Early suspicion, prompt diagnosis and intensive treatment will improve survival in thyroid storm patients. Because of its rarity and high mortality, prospective intervention studies for the treatment of thyroid storm are difficult to carry out. We, the Japan Thyroid Association and Japan Endocrine Society taskforce committee, previously developed new diagnostic criteria and conducted nationwide surveys for thyroid storm in Japan. Detailed analyses of clinical data from 356 patients revealed that the mortality in Japan was still high (∼11%) and that multiple organ failure and acute heart failure were common causes of death. In addition, multimodal treatment with antithyroid drugs, inorganic iodide, corticosteroids and beta-adrenergic antagonists has been suggested to improve mortality of these patients. Based on the evidence obtained by nationwide surveys and additional literature searches, we herein established clinical guidelines for the management of thyroid storm. The present guideline includes 15 recommendations for the treatment of thyrotoxicosis and organ failure in the central nervous system, cardiovascular system, and hepato-gastrointestinal tract, admission criteria for the intensive care unit, and prognostic evaluation. We also proposed preventive approaches to thyroid storm, roles of definitive therapy, and future prospective trial plans for the treatment of thyroid storm. We hope that this guideline will be useful for many physicians all over the world as well as in Japan in the management of thyroid storm and the improvement of its outcome.

  15. Solid state ionics: a Japan perspective

    PubMed Central

    Yamamoto, Osamu

    2017-01-01

    Abstract The 70-year history of scientific endeavor of solid state ionics research in Japan is reviewed to show the contribution of Japanese scientists to the basic science of solid state ionics and its applications. The term ‘solid state ionics’ was defined by Takehiko Takahashi of Nagoya University, Japan: it refers to ions in solids, especially solids that exhibit high ionic conductivity at a fairly low temperature below their melting points. During the last few decades of exploration, many ion conducting solids have been discovered in Japan such as the copper-ion conductor Rb4Cu16I7Cl13, proton conductor SrCe1–xYxO3, oxide-ion conductor La0.9Sr0.9Ga0.9Mg0.1O3, and lithium-ion conductor Li10GeP2S12. Rb4Cu16I7Cl13 has a conductivity of 0.33 S cm–1 at 25 °C, which is the highest of all room temperature ion conductive solid electrolytes reported to date, and Li10GeP2S12 has a conductivity of 0.012 S cm–1 at 25 °C, which is the highest among lithium-ion conductors reported to date. Research on high-temperature proton conducting ceramics began in Japan. The history, the discovery of novel ionic conductors and the story behind them are summarized along with basic science and technology. PMID:28804526

  16. Solid state ionics: a Japan perspective

    NASA Astrophysics Data System (ADS)

    Yamamoto, Osamu

    2017-12-01

    The 70-year history of scientific endeavor of solid state ionics research in Japan is reviewed to show the contribution of Japanese scientists to the basic science of solid state ionics and its applications. The term 'solid state ionics' was defined by Takehiko Takahashi of Nagoya University, Japan: it refers to ions in solids, especially solids that exhibit high ionic conductivity at a fairly low temperature below their melting points. During the last few decades of exploration, many ion conducting solids have been discovered in Japan such as the copper-ion conductor Rb4Cu16I7Cl13, proton conductor SrCe1-xYxO3, oxide-ion conductor La0.9Sr0.9Ga0.9Mg0.1O3, and lithium-ion conductor Li10GeP2S12. Rb4Cu16I7Cl13 has a conductivity of 0.33 S cm-1 at 25 °C, which is the highest of all room temperature ion conductive solid electrolytes reported to date, and Li10GeP2S12 has a conductivity of 0.012 S cm-1 at 25 °C, which is the highest among lithium-ion conductors reported to date. Research on high-temperature proton conducting ceramics began in Japan. The history, the discovery of novel ionic conductors and the story behind them are summarized along with basic science and technology.

  17. What Constitutes Traditional and Modern Eating? The Case of Japan.

    PubMed

    Sproesser, Gudrun; Imada, Sumio; Furumitsu, Isato; Rozin, Paul; Ruby, Matthew B; Arbit, Naomi; Fischler, Claude; Schupp, Harald T; Renner, Britta

    2018-01-25

    Traditional Japanese dietary culture might be a factor contributing to the high life expectancy in Japan. As little is known about what constitutes traditional and modern eating in Japan, the aims of the current study were to (1) comprehensively compile and systematize the various facets of traditional and modern eating; and (2) investigate whether these facets also apply to traditional and modern eating in Japan. In Study 1, an extensive international literature review was performed. Forty-five facets of traditional and modern eating were compiled and systematized into the dimensions of what and how people eat, and into eleven separate subdimensions. In Study 2, 340 adults from Japan answered a questionnaire. Results showed that traditional and modern eating in Japan is reflected in both what and how people eat. Within these two dimensions, ten subdimensions were found: the ingredients, processing, temporal origin, spatial origin, and variety of consumed foods, as well as temporal, spatial, and social aspects, appreciation, and concerns when eating. This study provides a broad compilation of facets of traditional and modern eating in Japan. Future research should investigate how these facets are related to life expectancy and health.

  18. What Constitutes Traditional and Modern Eating? The Case of Japan

    PubMed Central

    Imada, Sumio; Furumitsu, Isato; Rozin, Paul; Ruby, Matthew B.; Arbit, Naomi; Fischler, Claude; Schupp, Harald T.; Renner, Britta

    2018-01-01

    Traditional Japanese dietary culture might be a factor contributing to the high life expectancy in Japan. As little is known about what constitutes traditional and modern eating in Japan, the aims of the current study were to (1) comprehensively compile and systematize the various facets of traditional and modern eating; and (2) investigate whether these facets also apply to traditional and modern eating in Japan. In Study 1, an extensive international literature review was performed. Forty-five facets of traditional and modern eating were compiled and systematized into the dimensions of what and how people eat, and into eleven separate subdimensions. In Study 2, 340 adults from Japan answered a questionnaire. Results showed that traditional and modern eating in Japan is reflected in both what and how people eat. Within these two dimensions, ten subdimensions were found: the ingredients, processing, temporal origin, spatial origin, and variety of consumed foods, as well as temporal, spatial, and social aspects, appreciation, and concerns when eating. This study provides a broad compilation of facets of traditional and modern eating in Japan. Future research should investigate how these facets are related to life expectancy and health. PMID:29370081

  19. How sustainable is Japan's foreign aid policy? An analysis of Japan's official development assistance and funding for energy sector projects

    NASA Astrophysics Data System (ADS)

    Yamaguchi, Hideka

    Japan has adopted a sustainable development strategy since the late 1980s in the effort to address social and environmental damages caused by past Japan-funded projects in partner nations. Even after about a decade and a half of the policy implementation, however, there are few reports which critically examine effects of the adoption of the idea of sustainable development. This dissertation evaluates Japan's foreign aid policy to determine the extent to which new revisions of aid policy have improved the environmental sustainability of the policy. This dissertation reviews the mainstream idea of sustainable development (also known as the sustainable development paradigm in this dissertation) to reveal the nature of the idea of sustainable development that Japan's foreign aid policy depends on. A literature review of two development discourses---modernization theory and ecological modernization theory---and three types of critiques against the sustainable development paradigm---focused on adverse impacts of modern science, globalization, and environmental overuse---reveals core logics of and problems with the sustainable development paradigm. Japan's foreign aid policy impacts on energy sector development in recipient countries is examined by means of a quantitative analysis and a qualitative analysis. Specifically, it examines the effect of Japan's ODA program over fifteen years that proposed to facilitate sustainable development in developing countries. Special emphasis is given to investigation of ODA disbursements in the energy sector and detailed case studies of several individual energy projects are performed. The dissertation discovers that the sustainable development paradigm guiding Japan's ODA has little capacity to accomplish its goals to bring about social and ecological improvement in developing countries. This dissertation finds three fundamental weaknesses in Japanese ODA policy on energy sector development as well as the sustainable development

  20. Bunko: Private Mini-Libraries for Children in Japan.

    ERIC Educational Resources Information Center

    Takeuchi, Satoru

    "Bunko" are local mini-libraries for children in Japan, operated voluntarily by individuals or groups of parents, intended to nurture children's reading interest by offering them an inviting reading environment. In 1993, there were an estimated 4,000 bunko in Japan, with approximately 32,000 adult bunko members (90% female). Bunko…

  1. The present situation of prophylactic vaccination in Japan for travel abroad.

    PubMed

    Nakano, Takashi

    2008-11-01

    The current situation of vaccination in Japan is reviewed from a viewpoint of overseas travelers. Vaccinations before travel to developing countries, where the risk of infection is high, are recommended for two reasons: "individual protection" and "prevention of communicable disease importation". However, there are problems in Japan; some vaccines available commonly in foreign nations are not approved in Japan and the vaccination schedule is not convenient for travelers. Vaccination is sometimes needed also for travel to Europe and North America. This is because certain vaccinations are required for entering school or studying abroad. In Japan, there is no regulation which recommends vaccination as an entrance requirement. Compared with other nations, Japanese children receive fewer vaccines routinely. On the other hand, there are different features from other industrialized nations, such as routine childhood BCG vaccination and immunization against Japanese encephalitis in Japan. Compared with foreign nations, awareness as regards "travel medicine" is lower in Japan. Recognizing this situation will lead to improvement of vaccination of travelers.

  2. Okinawa, Japan

    NASA Image and Video Library

    1991-08-11

    The southern half of the island of Okinawa, Japan (26.5N, 128.0E) can be seen in this nearly cloud free view. Okinawa is part of the Ryuku Islands which extend from Taiwan northeastward to Kyushu, southernmost of the Japanese Home Islands. The large military base at Kadena, with large runways, is visible near the center of the scene. Kadena is one of several emergency landing sites around the world for the space shuttle.

  3. Radar Image, Hokkaido, Japan

    NASA Image and Video Library

    2000-05-18

    The southeast part of the island of Hokkaido, Japan, is an area dominated by volcanoes and volcanic caldera. The active Usu Volcano is at the lower right edge of the circular Lake Toya-Ko and near the center of the image.

  4. History Textbook Reform in Allied Occupation Japan, 1945-52.

    ERIC Educational Resources Information Center

    Thakur, Yoko H.

    1995-01-01

    Observes that, although textbook reform in occupied Japan originally supported democratic principles of openness and competition, it later became a mechanism for anticommunist censorship. Maintains that interpretations of Japan's military conduct remain highly politicized and controversial. (MJP)

  5. Continuity and Change in Disaster Education in Japan

    ERIC Educational Resources Information Center

    Kitagawa, Kaori

    2015-01-01

    This article aims to describe post-war continuity and change in disaster education in Japan. Preparedness for natural disasters has been a continuous agenda in Japan for geographical and meteorological reasons, and disaster education has been practised in both formal and informal settings. Post-war disaster management and education have taken a…

  6. Beyond the Limitations of Environmental Education in Japan

    ERIC Educational Resources Information Center

    Imamura, Mitsuyuki

    2017-01-01

    Environmental education has not spread as widely in Japan as expected and therefore has not had any significant impact on environmental problems, even though many educators and researchers have devoted themselves to environmental educational practice. Why is environmental education not popular in Japan, and what does this tell us? The purpose of…

  7. Activities of the Student Forum of the Geoinformation Forum Japan

    NASA Astrophysics Data System (ADS)

    Oba, A.; Miyazaki, H.

    2012-07-01

    This reports a history and future prospects of the activities by the Student Forum of the Geoinformation Forum Japan. For growths of academic fields, active communications among students and young scientists are indispensable. Several academic communities in geoinformation fields are established by youths and play important roles of building networks over schools and institutes. The networks are expected to be innovative cooperation after the youths achieve their professions. Although academic communities are getting fixed growth particularly in Japan, youths had gotten little opportunities to make contacts with youths themselves. To promote gotten youth activities among geoinformation fields, in 1998, we started a series of programs that named the Student Forum of the Geoinformation Forum Japan involving students and young scientists within the annual conferences, Geoinformation Forum Japan. The programs have provided opportunities to do presentation their studies by posters, some events, and motivations to create networks among students and young scientists. From 2009, some members of our activities set additional conference in west area of Japan. Thus our activities are spread within Japan. As a result of these achievements, the number of youth dedicating to the programs keeps growing. From 2009, it's getting international gradually, however, almost all the participants are still Japanese. To keep and expand the network, we are planning to make some nodes with some Asian youth organizations in the field of geoinformation. This paper is concluded with proposals and future prospects on the Student Forum of the Geoinformation Forum Japan.

  8. Connecting Higher Education Research in Japan with the International Academic Community

    ERIC Educational Resources Information Center

    Yonezawa, Akiyoshi

    2015-01-01

    This study examines the historical, current, and future challenges of higher education research in Japan within a global context. Japanese higher education research has been strongly influenced by the international academic community. At the same time, higher education researchers in Japan have participated in international projects, and Japan has…

  9. 75 FR 65213 - Removal of Varietal Restrictions on Apples From Japan

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-22

    ...-0020] RIN 0579-AD08 Removal of Varietal Restrictions on Apples From Japan AGENCY: Animal and Plant... the importation of Fuji variety apples from Japan to allow all varieties of Malus domestica apples... that the risk associated with allowing other varieties of M. domestica apples from Japan into the...

  10. 75 FR 11071 - Removal of Varietal Restrictions on Apples from Japan

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-10

    ... on Apples from Japan AGENCY: Animal and Plant Health Inspection Service, USDA. ACTION: Proposed rule... Japan to allow all varieties of Malus domestica apples into the United States under the same conditions... apples from Japan to be imported into the United States while continuing to protect against the...

  11. Developing Native Social Intuition in Preparation for an Internship in Japan.

    ERIC Educational Resources Information Center

    Yamashita, Margaret Y.

    The program of the Japan-American Institute of Management Sciences (JAIMS) in Hawaii, a nonprofit graduate-level institution intended to support training for cross-cultural business leadership, is described and discussed. Two curricula, the Japan-focused Master of Business Administration program and the Japan-focused Management Program are offered…

  12. Post-Flowering Nitrate Uptake in Wheat Is Controlled by N Status at Flowering, with a Putative Major Role of Root Nitrate Transporter NRT2.1

    PubMed Central

    Taulemesse, François; Le Gouis, Jacques; Gouache, David; Gibon, Yves; Allard, Vincent

    2015-01-01

    In bread wheat (Triticum aestivum L.), the simultaneous improvement of both yield and grain protein is difficult because of the strong negative relationship between these two traits. However, some genotypes deviate positively from this relationship and this has been linked to their ability to take up nitrogen (N) during the post-flowering period, regardless of their N status at flowering. The physiological and genetic determinants of post-flowering N uptake relating to N satiety are poorly understood. This study uses semi-hydroponic culture of cv. Récital under controlled conditions to explore these controls. The first objective was to record the effects of contrasting N status at flowering on post-flowering nitrate (NO3 -) uptake under non-limiting NO3 - conditions, while following the expression of key genes involved in NO3 - uptake and assimilation. We found that post-flowering NO3 - uptake was strongly influenced by plant N status at flowering during the first 300–400 degree-days after flowering, overlapping with a probable regulation of nitrate uptake exerted by N demand for growth. The uptake of NO3 - correlated well with the expression of the gene TaNRT2.1, coding for a root NO3 - transporter, which seems to play a major role in post-flowering NO3 - uptake. These results provide a useful knowledge base for future investigation of genetic variability in post-flowering N uptake and may lead to concomitant gains in both grain yield and grain protein in wheat. PMID:25798624

  13. International HIV and AIDS prevention: Japan/United States collaboration.

    PubMed

    Umenai, T; Narula, M; Onuki, D; Yamamoto, T; Igari, T

    1997-01-01

    As the epicenter of the HIV/AIDS pandemic shifts from Africa to Asia, Japan is becoming ever more aware of the importance of containing and preventing spread of the virus. International collaboration, particularly with the United States, is a logical approach because it allows utilization of expertise from countries in other stages of the pandemic, can prevent duplication of efforts, and complements efforts of the other countries. Further, both Japan and the United States can use their combined influence and prestige to encourage cooperation among all nations. In 1994, Japan established the Global Issues Initiative to extend cooperation to developing countries in the areas of population and AIDS control. It has disbursed more than $460 million (U.S.$) to promote active cooperation and stimulate international attention to the importance of addressing these health issues. Japan has established four main programs for international collaboration for control of HIV and AIDS, three operated by ministries and one by a Japanese nongovernmental organization. Japanese/United States collaboration is developing through the United States/Japan Cooperative Medical Sciences Program, the Common Agenda for Cooperation in Global Perspective, the Paris Summit, and the United Nations Joint Programme on AIDS. It is critical that Japan and the United States, as the two largest donors to international development, demonstrate, through their collaboration, ways to maximize the use of limited resources, reduce duplication, and promote sustainable development programs in which HIV prevention and AIDS care programs are systemically integrated.

  14. SMOS near-real-time soil moisture product: processor overview and first validation results

    NASA Astrophysics Data System (ADS)

    Rodríguez-Fernández, Nemesio J.; Muñoz Sabater, Joaquin; Richaume, Philippe; de Rosnay, Patricia; Kerr, Yann H.; Albergel, Clement; Drusch, Matthias; Mecklenburg, Susanne

    2017-10-01

    Measurements of the surface soil moisture (SM) content are important for a wide range of applications. Among them, operational hydrology and numerical weather prediction, for instance, need SM information in near-real-time (NRT), typically not later than 3 h after sensing. The European Space Agency (ESA) Soil Moisture and Ocean Salinity (SMOS) satellite is the first mission specifically designed to measure SM from space. The ESA Level 2 SM retrieval algorithm is based on a detailed geophysical modelling and cannot provide SM in NRT. This paper presents the new ESA SMOS NRT SM product. It uses a neural network (NN) to provide SM in NRT. The NN inputs are SMOS brightness temperatures for horizontal and vertical polarizations and incidence angles from 30 to 45°. In addition, the NN uses surface soil temperature from the European Centre for Medium-Range Weather Forecasts (ECMWF) Integrated Forecast System (IFS). The NN was trained on SMOS Level 2 (L2) SM. The swath of the NRT SM retrieval is somewhat narrower (˜ 915 km) than that of the L2 SM dataset (˜ 1150 km), which implies a slightly lower revisit time. The new SMOS NRT SM product was compared to the SMOS Level 2 SM product. The NRT SM data show a standard deviation of the difference with respect to the L2 data of < 0.05 m3 m-3 in most of the Earth and a Pearson correlation coefficient higher than 0.7 in large regions of the globe. The NRT SM dataset does not show a global bias with respect to the L2 dataset but can show local biases of up to 0.05 m3 m-3 in absolute value. The two SMOS SM products were evaluated against in situ measurements of SM from more than 120 sites of the SCAN (Soil Climate Analysis Network) and the USCRN (US Climate Reference Network) networks in North America. The NRT dataset obtains similar but slightly better results than the L2 data. In summary, the NN SMOS NRT SM product exhibits performances similar to those of the Level 2 SM product but it has the advantage of

  15. Star Week- A Successful Campaign in Japan -

    NASA Astrophysics Data System (ADS)

    Watanabe, J.

    2006-08-01

    In 1995, we started a campaign of the star week as between August 1 and 7 when it is usually expected that most part of Japan should be good weather after the rainy season during the summer holiday. Several hundreds of astronomical facilities for general public in Japan, including planetariums, museums, and public observatories participated in our campaign, together with make good collaborations for education purpose. More than 200 astronomical events such as star parties were coordinated for general public every year. Japan is one of the worst countries for light pollution. Especially most of children have no experience of seeing Milky Way. Let them see the real stars. Let them feel the universe by inviting them to the related astronomical facilities located all over Japan. For realizing this purpose, it is better to set the special week, similar to the "Bird Week" by arranging various astronomical events in these facilities in order to invite all the general public. This is the motivation of the beginning of the star week. Such outreach program should give opportunity for general public to understand the excitement of the astronomy. In this paper, we will introduce present situation of our campaign, along with some statistics.

  16. Effect of nicotine patches in pregnancy on infant and maternal outcomes at 2 years: follow-up from the randomised, double-blind, placebo-controlled SNAP trial.

    PubMed

    Cooper, Sue; Taggar, Jaspal; Lewis, Sarah; Marlow, Neil; Dickinson, Anne; Whitemore, Rachel; Coleman, Tim

    2014-09-01

    The SNAP (Smoking and Nicotine in Pregnancy) trial compared nicotine replacement therapy (NRT) patches with placebo in pregnant smokers; although NRT doubled cessation rates in the first 4 weeks, by delivery no differences in maternal smoking or birth outcomes were noted. As a result, NRT used in standard doses during pregnancy is considered ineffective for smoking cessation. Subsequent effects of NRT on the children of treated mothers are unknown because no trials have investigated the effect of gestational NRT use beyond birth. To assess whether NRT use in pregnancy might cause harm to infants, we aimed to compare effects of NRT and placebo on infant development 2 years after delivery. 1050 pregnant smokers aged 16-45 years, at 12-24 weeks' gestation, and smoking at least five cigarettes per day were recruited from seven hospitals in England between May 1, 2007, and Feb 26, 2010, and followed up until their infants were 2 years old. Participants were randomly assigned (1:1) to receive up to 8-weeks treatment with NRT (15 mg/16 h transdermal patches) or identically packaged and visually matched placebo patches (all patches manufactured by and purchased at market rate from United Pharmaceuticals, Amman, Jordan), issued as two 4-week supplies (521 for NRT group, 529 for placebo group) [Corrected]. Randomisation was stratified by site with participants, health-care professionals, and research staff masked to treatment allocation. The primary results for participants and infants at delivery were published in 2012; we present results from the trial cohort 2 years after birth. After delivery, questionnaires were posted to participants and, if there was no response, to family physicians. The primary outcome at 2 years was infants' survival without developmental impairment (ie, no disability or problems with behaviour or development). Treatment groups were compared on an intention-to-treat basis. The trial is registered with Controlled-Trials.com, number ISRCTN07249128

  17. Taeniasis and cysticercosis due to Taenia solium in Japan.

    PubMed

    Yanagida, Tetsuya; Sako, Yasuhito; Nakao, Minoru; Nakaya, Kazuhiro; Ito, Akira

    2012-01-17

    Taenia solium is a zoonotic cestode that causes taeniasis and cysticercosis in humans. The parasite is traditionally found in developing countries where undercooked pork is consumed under poor sanitary conditions and/or as part of traditional food cultures. However, the recent increase in international tourism and immigration is spreading the disease into non-endemic developed countries such as the United States. Although there has been concern that the number of cysticercosis cases is increasing in Japan, the current situation is not clear. This is largely because taeniasis and cysticercosis are not notifiable conditions in Japan and because there have been no comprehensive reviews of T. solium infections in Japan conducted in the last 15 years. Herein, we provide an overview of the status of T. solium infection in Japan over the past 35 years and point out the potential risks to Japanese society.

  18. 76 FR 798 - Ball Bearings From Japan and the United Kingdom

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-06

    ... Remand)] Ball Bearings From Japan and the United Kingdom AGENCY: United States International Trade... determination in the five-year review of the antidumping duty order on ball bearings from Japan. For further... Certain Bearings and Parts Thereof from Japan and the United Kingdom, Inv. Nos. 731-TA-394-A & 399-A...

  19. 75 FR 30856 - Ball Bearings From Japan and the United Kingdom

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-02

    ... Remand)] Ball Bearings From Japan and the United Kingdom AGENCY: United States International Trade... determinations in the five-year reviews of the antidumping orders on ball bearings from Japan and the United... Certain Bearings and Parts Thereof From Japan and the United Kingdom, Inv. Nos. 731-TA- 394-A & 399-A...

  20. 76 FR 76760 - Gray Portland Cement and Cement Clinker From Japan

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-08

    ... and Cement Clinker From Japan Determination On the basis of the record \\1\\ developed in the subject... duty order on gray Portland cement and cement clinker from Japan would be likely to lead to... and Cement Clinker from Japan: Investigation No. 731- TA-461 (Third Review). By order of the...

  1. Nuclear Power in Japan.

    ERIC Educational Resources Information Center

    Powell, John W.

    1983-01-01

    Energy consumption in Japan has grown at a faster rate than in any other major industrial country. To maintain continued prosperity, the government has embarked on a crash program for nuclear power. Current progress and issues/reactions to the plan are discussed. (JN)

  2. Akashi Kaikyo Bridge, Japan

    NASA Image and Video Library

    2013-03-25

    NASA Terra spacecraft shows the Akashi Kaikyo Bridge or Pearl Bridge, the longest central span of any suspension bridge in the world, at 1991 meters, connecting the city of Kobe, Japan with Iwaja on Awaji Island by crossing the busy Akashi Strait.

  3. 78 FR 60897 - Certain Welded Large Diameter Line Pipe From Japan

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-02

    ... Diameter Line Pipe From Japan Determination On the basis of the record \\1\\ developed in the subject five... order on certain welded large diameter line pipe from Japan would likely to lead to continuation or... Line Pipe from Japan: Investigation No. 731-TA-919 (Second Review). By order of the Commission. Issued...

  4. Trade, Foreign Investment, and Competitiveness. The Japan Business Study Program. Based on a Seminar Series entitled "Japan Business Study Program 1989" (Austin, Texas, October 12-27, 1989).

    ERIC Educational Resources Information Center

    Matsuo, Hirofumi, Ed.

    Seven articles are presented addressing topics related to United States-Japan trade, foreign investment, and U.S. competitiveness in the global market. The first article, "Super 301 and the Changing Japan-American Relationship" by Glenn Davis describes recent U.S.-Japan trade frictions, epitomized by Super 301, and explains the influence…

  5. Media Education in Japan (Retrospect and Present Trends).

    ERIC Educational Resources Information Center

    Takakuwa, Yasuo

    This overview of the development of media education in Japan begins with a discussion of the motion picture as entertainment and the public attitude toward film in Japan during the early years of the century. The introduction of film education into the schools in the 1920s--both teaching by film and teaching about film--is then described together…

  6. High-level manpower movement and Japan's foreign aid.

    PubMed

    Furuya, K

    1992-01-01

    "Japan's technical assistance programs to Asian countries are summarized. Movements of high-level manpower accompanying direct foreign investments by private enterprise are also reviewed. Proposals for increased human resources development include education and training of foreigners in Japan as well as the training of Japanese aid experts and the development of networks for information exchange." excerpt

  7. Japan: Super-Aging Society Preparing for the Future

    ERIC Educational Resources Information Center

    Muramatsu, Naoko; Akiyama, Hiroko

    2011-01-01

    Japan has the highest proportion of older adults in the world. Aging is not only an immediate personal issue but also a salient factor in crucial public policies, such as pensions, health, and long-term care. The Great East Japan Earthquake, tsunami, and nuclear power plant disaster of March 2011 has highlighted current and emerging issues of a…

  8. Over-Education and Its Opportunity Cost in Japan

    ERIC Educational Resources Information Center

    Kucel, Aleksander; Molina, Ivette Fuentes; Raya, Josep Maria

    2016-01-01

    In this paper, we investigate the determinants of over-education in Japan and evaluate its opportunity costs for university graduates. To this end, we use the REFLEX data. Results reveal that over-education level in Japan is high and it brings an important wage penalty for Japanese workers. Large firm and high occupations point toward a…

  9. Effectiveness of rotavirus vaccines against hospitalisations in Japan.

    PubMed

    Fujii, Yoshiyuki; Noguchi, Atsuko; Miura, Shinobu; Ishii, Haruka; Nakagomi, Toyoko; Nakagomi, Osamu; Takahashi, Tsutomu

    2017-07-11

    In Japan, rotavirus hospitalisation occurs at a rate from 2.8 to 13.7 per 1000 child-years among children age less than 5 years, and it imposes a substantial burden to the healthcare system in the country. While both monovalent (RV1) and pentavalent (RV5) rotavirus vaccines are licensed in Japan, neither has been incorporated in the national infant immunization programme. In this study, we estimated vaccine effectiveness (VE) in Japan. This study was conducted in Yuri-Kumiai General Hospital located in a city in the north-western part of Japan. Age-eligible children for rotavirus vaccination were enrolled if they were hospitalized for rotavirus gastroenteritis between September 2013 and August 2016. Rotavirus gastroenteritis was defined by the detection of rotavirus antigen by immunochromatography. "Vaccinated" was defined as infant inoculated with at least one dose of either RV1 or RV5. A conditional logistic regression analysis was performed by modelling the year of birth, year of admission, residence of the children and vaccination status, and by matching the age of cases with that of test-negative controls. The adjusted odds ratio of the vaccinated over unvaccinated was then used to calculate VE in the formula of (1 - adjusted odds ratio) × 100. Out of the 244 patients enrolled, rotavirus antigen was detected in 55 (22.5%) of whom 10 (18.2%) were vaccinated, whereas 94 (49.7%) of 189 test-negative controls were vaccinated. During the study period, the vaccine uptake rate in the controls increased from 36.2% to 61.8%. On the other hand, the vaccination coverage over the three years was 64.2% in Yuri-Honjo city (three quarters of the catchment), and 91.4% in Nikaho city (one quarter of the catchment). The VE was calculated to be 70.4% (95% confidence interval: 36.0-86.4%, P = 0.002). The point estimate of the VE was lower but its 95% confidence interval overlaps those of the efficacies obtained from clinical trials in Japan. The rotavirus vaccine was

  10. Improving adherence to web-based cessation programs: a randomized controlled trial study protocol

    PubMed Central

    2013-01-01

    Background Reducing smoking prevalence is a public health priority that can save more lives and money than almost any other known preventive intervention. Internet interventions have the potential for enormous public health impact given their broad reach and effectiveness. However, most users engage only minimally with even the best designed websites, diminishing their impact due to an insufficient ‘dose’. Two approaches to improve adherence to Internet cessation programs are integrating smokers into an online social network and providing free nicotine replacement therapy (NRT). Active participation in online communities is associated with higher rates of cessation. Integrating smokers into an online social network can increase support and may also increase utilization of cessation tools and NRT. Removing barriers to NRT may increase uptake and adherence, and may also increase use of online cessation tools as smokers look for information and support while quitting. The combination of both strategies may exert the most powerful effects on adherence compared to either strategy alone. Methods/Design This study compares the efficacy of a smoking cessation website (WEB) alone and in conjunction with free NRT and a social network (SN) protocol designed to integrate participants into the online community. Using a 2 (SN, no SN) x 2 (NRT, no NRT) randomized, controlled factorial design with repeated measures at baseline, 3 months, and 9 months, this study will recruit N = 4,000 new members of an internet cessation program and randomize them to: 1) WEB, 2) WEB + SN, 3) WEB + NRT, or 4) WEB + SN + NRT. Hypotheses are that all interventions will outperform WEB and that WEB + SN + NRT will outperform WEB + NRT and WEB + SN on 30-day point prevalence abstinence at 9 months. Exploratory analyses will examine theory-driven hypotheses about the mediators and moderators of outcome. Discussion Addressing adherence in internet cessation programs is critical and timely to leverage

  11. 78 FR 58997 - Chlorinated Isocyanurates From Japan: Initiation of Antidumping Duty Investigation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-25

    ... From Japan: Initiation of Antidumping Duty Investigation AGENCY: Import Administration, International... (``AD'') petition concerning imports of chlorinated isocyanurates (``chlorinated isos'') from Japan... Japan, dated August 29, 2013 (``Petition''). \\2\\ See First Supplement to the AD Petition, dated...

  12. General practitioners' beliefs about effectiveness and intentions to prescribe smoking cessation medications: qualitative and quantitative studies

    PubMed Central

    Vogt, Florian; Hall, Sue; Marteau, Theresa M

    2006-01-01

    Background General practitioners' (GPs) negative beliefs about nicotine dependence medications may act as barriers to prescribing them. Methods Study1: Twenty-five GPs from 16 practices across London were interviewed in this qualitative study. Framework analysis was used to identify key themes. Study 2: A convenience sample of 367 GPs completed an internet-based survey. Path-analysis was used to examine the relations between beliefs and intentions to prescribe smoking cessation medications. Results Study 1: Whilst nicotine replacement therapy (NRT) and bupropion were generally perceived as effective and cost-effective, the effectiveness of NRT was seen as critically dependent on behavioural support for smoking cessation. This dependence appeared to be influenced by perceptions that without support smokers would neglect psychological aspects of smoking and use NRT incorrectly. GPs perceived bupropion as dangerous and were concerned about its side-effects. Study 2: GPs' beliefs had medium (NRT, f2 = .23) to large (bupropion, f2=.45; NRT without support, f2=.59) effects on their intentions to prescribe medications. Beliefs about effectiveness of NRT and bupropion and the perceived danger of bupropion were the key predictors of intentions to prescribe NRT and bupropion, respectively. Beliefs about neglecting psychological aspects of smoking and incorrect use had indirect effects on intentions to prescribe NRT without support, operating via beliefs about effectiveness. Conclusion GPs vary in their beliefs about the effectiveness and safety of smoking cessation medications. Their intentions to prescribe these medications vary in line with these beliefs. Interventions aimed at increasing the likelihood with which GPs prescribe these medications may be more effective if they addressed these beliefs. PMID:17092346

  13. Expression of a functional hyperpolarization-activated current (Ih) in the mouse nucleus reticularis thalami.

    PubMed

    Rateau, Y; Ropert, N

    2006-05-01

    The GABAergic neurons of the nucleus reticularis thalami (nRT) express the type 2 hyperpolarization-activated cAMP-sensitive (HCN2) subunit mRNA, but surprisingly, they were reported to lack the hyperpolarization-activated (Ih) current carried by this subunit. Using the voltage-clamp recordings in the thalamocortical slice preparation of the newborn and juvenile mice (P6-P23), we demonstrate that, in the presence of 1 mM barium (Ba2+), the nRT neurons express a slow hyperpolarization-activated inward current, suggesting that the Ih is present but masked in control conditions by K+ leak currents. We investigate the identity of the hyperpolarization-activated current in the nRT by studying its physiological and pharmacological profile in presence of Ba2+. We show that it has voltage- and time-dependent properties typical of the Ih, that it is blocked by cesium and ZD7288, two blockers of the Ih, and that it is carried both by the K+ and Na+ ions. We could also alter the gating characteristics of the hyperpolarization-activated current in the nRT by adding a nonhydrolysable analogue of cAMP to the pipette solution. Finally, using the current-clamp recording, we showed that blocking the hyperpolarization-activated current induced an hyperpolarization correlated with an increase of the R(in) of the nRT neurons. In conclusion, our results demonstrate that the nRT neurons express the Ih with slow kinetics similar to those described for the homomeric HCN2 channels, and we show that the Ih of the nRT contributes to the excitability of the nRT neurons in normal conditions.

  14. Cancer incidence and incidence rates in Japan in 2009: a study of 32 population-based cancer registries for the Monitoring of Cancer Incidence in Japan (MCIJ) project.

    PubMed

    Hori, Megumi; Matsuda, Tomohiro; Shibata, Akiko; Katanoda, Kota; Sobue, Tomotaka; Nishimoto, Hiroshi

    2015-09-01

    The Japan Cancer Surveillance Research Group aimed to estimate the cancer incidence in Japan in 2009 based on data collected from 32 of 37 population-based cancer registries, as part of the Monitoring of Cancer Incidence in Japan (MCIJ) project. The incidence of only primary invasive cancer in Japan for 2009 was estimated to be 775 601. Stomach cancer and breast cancer were the leading types of cancer in males and females, respectively. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  15. Anxiety Sensitivity and Nicotine Replacement Therapy Side Effects: Examining the Role of Emotion Dysregulation Among Treatment-Seeking Smokers.

    PubMed

    Zvolensky, Michael J; Paulus, Daniel J; Garey, Lorra; Raines, Amanda M; Businelle, Michael; Shankman, Stewart A; Manning, Kara; Goodwin, Renee D; Schmidt, Norman B

    2017-11-01

    Nicotine replacement therapy (NRT) significantly increases the likelihood of quit success at least over the short term, yet some smokers prematurely discontinue use. NRT side effects are often cited as the primary reason for medication discontinuation. The current study examined a theoretical pathway by which two smoking-related emotional vulnerabilities (anxiety sensitivity and emotion dysregulation) were related to the number of NRT (nicotine patch) side effects reported 1 week following a scheduled quit attempt. It was hypothesized that anxiety sensitivity would have an indirect effect on NRT side effects through emotion dysregulation. A total of 179 treatment-seeking, adult daily smokers with elevated anxiety sensitivity (47.5% male; M age = 39.73 years, SD = 13.87) were enrolled in a smoking cessation trial. Covariate-adjusted analyses provided support for the hypothesized pathway, such that emotion dysregulation explained the association between anxiety sensitivity and NRT side effects (b = 0.02, SE = 0.01, 95% CI [0.002, 0.03]; completely standardized estimate = .15). The findings underscore the importance of developing cessation treatments that incorporate techniques to enhance emotion regulation, particularly among smokers higher in anxiety sensitivity, to decrease the risk of NRT side effects.

  16. Neo-Liberalism and Change in Higher Education Policy: England and Japan

    ERIC Educational Resources Information Center

    Yokoyama, Keiko

    2008-01-01

    The study scrutinizes the rationale behind higher education policy change in England and Japan, giving attention to stakeholders' perspective and legitimacy, policy network, and policy sphere. It argues that change in higher education policy in England and Japan towards being more market-oriented in the 1980s (England) and the 1990s (Japan) can…

  17. Timing of Neogene Manganese Deposit Formation in the Paleo-Japan Sea, northeast Japan

    NASA Astrophysics Data System (ADS)

    Ito, T.; Orihashi, Y.; Yanagisawa, Y.; Sakai, S.; Motoyama, I.; Kamikuri, S. I.; Komuro, K.; Suzuki, K.

    2017-12-01

    The generation ages of the two Neogene manganese deposits in northeast Japan were determined by diatom and radiolarian biostratigraphic analyses and zircon U-Pb dating. The manganese deposits analyzed were from the Kitaichi and Maruyama mines in the Fukaura district, northeast Japan. Manganese oxide layers of 0.5 m (Kitaichi) and 1.5 m (Maruyama) in thickness were predominantly composed of todorokite and occur conformably within volcanogenic sediments, which stratigraphically had correlated to middle Miocene in previous studies. The ages of the manganese oxide layers were 12.4 Ma. There was no time gap between the Kitaichi and the Maruyama manganese oxide layers, between the manganese oxide layer and the underlying tuffaceous sandstone in the Kitaichi mine, or within the manganese oxide layer of ca. 1.5 m thickness in the Maruyama mine. On the other hand, the overlying tuffaceous sandstone was dated at 4.5 Ma. The results suggest that the manganese oxide layers were formed immediately after the deposition of the tuffaceous sandstone at 12.4 Ma and that the restricted supply of volcanogenic and/or other detrital matter had kept for a long time (ca. 7 m.y.). The timing of the manganese deposit generation, 12.4 Ma, is identical to the age of the base of the Onnagawa Stage on the Nishikurosawa Stage in the Neogene stratotype section on the Japan Sea side, northeast Japan. And this is equivalent to the age of the start of diatom blooming. Paleogeographically, the manganese oxide deposition happened in a shallower area on a paleo-hill or a small island surrounded by stagnant mid to deep basins with diatom and organically carbon-rich, laminated, and fine-grained mud. It is highly probable that upwelling of mid to deep water rich in both dissolved manganese and nutrients is the trigger for the manganese deposit generation in shallower areas and the deposition of diatomaceous sediments in mid and deep basins. Eustatic regression might be the reason for the short

  18. Estimating the burden of foodborne diseases in Japan

    PubMed Central

    Kumagai, Yuko; Gilmour, Stuart; Ota, Erika; Momose, Yoshika; Onishi, Toshiro; Bilano, Ver Luanni Feliciano; Kasuga, Fumiko; Sekizaki, Tsutomu

    2015-01-01

    Abstract Objective To assess the burden posed by foodborne diseases in Japan using methods developed by the World Health Organization’s Foodborne Disease Burden Epidemiology Reference Group (FERG). Methods Expert consultation and statistics on food poisoning during 2011 were used to identify three common causes of foodborne disease in Japan: Campylobacter and Salmonella species and enterohaemorrhagic Escherichia coli (EHEC). We conducted systematic reviews of English and Japanese literature on the complications caused by these pathogens, by searching Embase, the Japan medical society abstract database and Medline. We estimated the annual incidence of acute gastroenteritis from reported surveillance data, based on estimated probabilities that an affected person would visit a physician and have gastroenteritis confirmed. We then calculated disability-adjusted life-years (DALYs) lost in 2011, using the incidence estimates along with disability weights derived from published studies. Findings In 2011, foodborne disease caused by Campylobacter species, Salmonella species and EHEC led to an estimated loss of 6099, 3145 and 463 DALYs in Japan, respectively. These estimated burdens are based on the pyramid reconstruction method; are largely due to morbidity rather than mortality; and are much higher than those indicated by routine surveillance data. Conclusion Routine surveillance data may indicate foodborne disease burdens that are much lower than the true values. Most of the burden posed by foodborne disease in Japan comes from secondary complications. The tools developed by FERG appear useful in estimating disease burdens and setting priorities in the field of food safety. PMID:26478611

  19. [Comparison between transmission of modern western medicine in China and Japan].

    PubMed

    Liu, Yuan-Ming

    2009-05-01

    In the middle period of the 16th century, western medicine had been introduced successively into China and Japan by the medium of Catholic missionaries. The transmission mode of western medicine in the two countries differed dramatically from each other due to the political, economic and social cultural differences of that time. In China, the transmission of western medicine focused on the theory first and transferred to the practical use later; while in Japan, it began with clinical treatment, then rose from the technology to the theory. As a result, the cognition to the western medical knowledge and medical system as well as the transplanting and localization in China and Japan were significantly different. The local western medical groups emerged earlier in Japan than in China, and the attitude toward western medicine was also more positive and a national health system was quickly established. The corresponding situation in China obviously lagged behind the one in Japan, and China learned from the successful experiences of Japan for a time.

  20. Five-Year Outcomes of the First Pivotal Clinical Trial of Balloon-Expandable Transcatheter Aortic Valve Replacement in Japan (PREVAIL JAPAN).

    PubMed

    Sawa, Yoshiki; Takayama, Morimasa; Goto, Tsuyoshi; Takanashi, Shuichiro; Komiya, Tatsuhiko; Tobaru, Tetsuya; Maeda, Koichi; Kuratani, Toru; Sakata, Yasushi

    2017-07-25

    Transcatheter aortic valve replacement (TAVR) has been an alternative less invasive therapy for high-surgical risk/inoperable patients with aortic valve stenosis (AS) in Japan. We report 5-year outcomes of the first pivotal clinical trial of TAVR in Japan (PREVAIL JAPAN).Methods and Results:A total of 64 patients with AS who were considered unsuitable candidates for surgery were enrolled at 3 centers in Japan (mean age: 84.3±6.1 years, female: 65.6%, STS score: 9.0±4.5%). Transfemoral approach (TF) and transapical approach (TA) was performed in 37 patients and 27 patients, respectively. At 5 years, freedom from all-cause death was 52.7% (TF: 51.3%, TA: 56.3%). Risk of all stroke at 5-year was 15.8% (TF: 8.9%, TA: 25.5%) and risk of major adverse cardiac and cerebrovascular events at 5 years was 58.0% (TF: 51.3%, TA: 69.2%). Mild or greater aortic regurgitation (AR) at 1 week was not associated with increased all-cause death at 5 years (69.1%) compared with none or trace AR (48.3%) (P=0.184). Patients with high STS score (>8) had higher mortality rate than those with low STS scores (≤8). The 5-year data from PREVAIL JAPAN show the clinical benefit of TAVR and suggest that balloon-expandable TAVR is an effective treatment option for Japanese patients with severe AS who are not suitable for surgery. (Funded by Edwards Lifesciences Limited; ClinicalTrials.gov number, NCT01113983.).

  1. Current status of portal vein thrombosis in Japan: Results of a questionnaire survey by the Japan Society for Portal Hypertension.

    PubMed

    Kojima, Seiichiro; Watanabe, Norihito; Koizumi, Jun; Kokubu, Shigehiro; Murashima, Naoya; Matsutani, Shoichi; Obara, Katsutoshi

    2018-03-01

    To investigate the current status of portal vein thrombosis (PVT) in Japan, the Clinical Research Committee of the Japan Society of Portal Hypertension undertook a questionnaire survey. A questionnaire survey of 539 cases of PVT over the previous 10 years was carried out at institutions affiliated with the Board of Trustees of the Japan Society of Portal Hypertension. The most frequent underlying etiology of PVT was liver cirrhosis in 75.3% of patients. Other causes included inflammatory diseases of the hepatobiliary system and the pancreas, malignant tumors, and hematologic diseases. The most frequent site was the main trunk of the portal vein (MPV) in 70.5%, and complete obstruction of the MPV was present in 11.5%. Among the medications for PVT, danaparoid was given to 45.8%, warfarin to 26.2%, heparin to 17.3%, and anti-thrombin III to 16.9%. Observation of the course was practiced in 22.4%. Factors contributing to therapeutic efficacy were implementation of various medications, thrombi localized to either the right or left portal vein only, non-complete obstruction of the MPV and Child-Pugh class A liver function. A survival analysis showed that the prognosis was favorable with PVT disappearance regardless of treatment. The questionnaire survey showed the current status of PVT in Japan. Any appropriate medication should be given to a patient with PVT when PVT is recognized. It is necessary to compile a large amount of information and reach a consensus on safe and highly effective management of PVT. © 2017 The Japan Society of Hepatology.

  2. Taeniasis and cysticercosis due to Taenia solium in Japan

    PubMed Central

    2012-01-01

    Taenia solium is a zoonotic cestode that causes taeniasis and cysticercosis in humans. The parasite is traditionally found in developing countries where undercooked pork is consumed under poor sanitary conditions and/or as part of traditional food cultures. However, the recent increase in international tourism and immigration is spreading the disease into non-endemic developed countries such as the United States. Although there has been concern that the number of cysticercosis cases is increasing in Japan, the current situation is not clear. This is largely because taeniasis and cysticercosis are not notifiable conditions in Japan and because there have been no comprehensive reviews of T. solium infections in Japan conducted in the last 15 years. Herein, we provide an overview of the status of T. solium infection in Japan over the past 35 years and point out the potential risks to Japanese society. PMID:22248435

  3. From bloodletting to apheresis in Japan.

    PubMed

    Mazda, Toshio; Schmidt, Paul J

    2010-02-01

    The ancient therapy of bloodletting that was universal in the West traveled to Japan 500 years ago on the trading vessels that carried physicians and barber-surgeons to care for the body and Christian missionaries to care for the soul. Then bloodletting was replaced by blood transfusion in the 19th century, only to return less than 50 years ago as apheresis. An understanding of those transitions can be gained from the story of the introduction of Western medicine to Japan and the events that have led to the practice of apheresis there today. (c) 2009 Elsevier Ltd. All rights reserved.

  4. Endangered vascular plants in Japan

    PubMed Central

    Iwatsuki, Kunio

    2008-01-01

    The history of the Red List of Japanese vascular plants is briefly reviewed for editing and research. Especially on the results of recent monitoring, the present status of information and conservation activities on the endangered plants in Japan is discussed and the dynamics of the Japanese flora are taken up, in relation to basic research on plant biodiversity on the Japanese Archipelago. The figures of endangered plants are not very variable during the past quarter of a century, but we can surmise that the conservation of threatened species in Japan has been promoted to some extent. Based on the results of such a study, proposals are made to contribute to the sustainable use of plant biodiversity on the Japanese Archipelago under a global conspectus. PMID:18941303

  5. Japan-U.S. Relations: Issues for Congress

    DTIC Science & Technology

    2009-09-02

    U.S.-Japan FTA With the conclusion of negotiations on a U.S.-South Korean free trade agreement (KORUS FTA ) on April 1, 2007, and the formation of...block that would result over the issue of agricultural policy.10 The DPJ’s 2009 election manifesto calls for the negotiation of a U.S.-Japan FTA ...participants could not agree on the modalities that negotiators would use to determine how much they would liberalize their agricultural markets and reduce

  6. Historical Development of Media Systems. I. Japan. Communication and Society 1.

    ERIC Educational Resources Information Center

    Ito, Shinichi; And Others

    This report presents an insight into indigenous media forms and the introduction of modern media in Japan, and follows media development through the war and occupation to the present day. The report discusses (1) the birth of the newspaper in Japan, (2) control laws and regulations, (3) press policy under the allied forces' occupation of Japan,…

  7. Clinical statistics of gynecologic cancers in Japan.

    PubMed

    Yamagami, Wataru; Nagase, Satoru; Takahashi, Fumiaki; Ino, Kazuhiko; Hachisuga, Toru; Aoki, Daisuke; Katabuchi, Hidetaka

    2017-03-01

    Cervical, endometrial, and ovarian cancers, have both high morbidity and mortality among the gynecologic malignant tumors in Japan. The present study was conducted using both the population-based cancer registry and the gynecologic cancer registry to elucidate the characteristics of gynecologic malignant tumors in Japan. Based on nationwide estimates from the population-based cancer registry in Japan, the morbidities and mortality of cervical, endometrial, and ovarian cancers were obtained and used for analysis. Clinicopathologic factors for cervical cancer, endometrial cancer, ovarian cancer, including age, clinical stage, postsurgical stage, histological type, therapeutic strategy, and prognosis were retrieved from the gynecologic cancer registry published by the Japan Society of Obstetrics and Gynecology and used for analysis. The morbidities of cervical, endometrial, and ovarian cancers were 10,908, 13,606, and 9,384 women in 2012, respectively. The prevalence of endometrial cancer has significantly and consistently been increasing and represents the most common gynecologic malignant tumor in Japan. The mortalities of cervical, endometrial, and ovarian cancers were 2.1, 1.3, and 3.2 per 100,000 in 2012, respectively. In 2014, 52.2% of cervical cancer patients were classified as stage I, 22.5% as stage II, 10.2% as stage III, and 11.2% as stage IV. In addition, 71.9% of endometrial cancer patients were classified as stage I, 6.0% as stage II, 13.3% as stage III, and 7.5% as stage IV. Finally, 43.2% of ovarian cancer patients were classified as stage I, 9.1% as stage II, 27.6% as stage III, and 7.2% as stage IV. Twelve-point six percent of ovarian cancer patients received neoadjuvant chemotherapy. Copyright © 2017. Asian Society of Gynecologic Oncology, Korean Society of Gynecologic Oncology.

  8. EFL Learners' Uses of Adverbs in Argumentative Essays

    ERIC Educational Resources Information Center

    Yilmaz, Ercan; Dikilitas, Kenan

    2017-01-01

    Adverbs require a great deal of effort to be mastered, and even the most advanced users of that language have difficulty in using them correctly (Narita & Sugiura, 2006; Peacock, 2010; Lei, 2012; Leedham & Cai, 2013). The purpose of this study is to find out to what extent relatively high proficiency level EFL learners use different types…

  9. Energy Demand and Resources of Japan. Volume I

    DTIC Science & Technology

    1973-08-01

    political motives. Economically Japan would prefer to develop alternative sources of petroleum which are politically stable and geologically viable...situation in the next decade. History records, therefore, Jhat Japan did not suddenly burst upon the scene as an advanced technology, highly competitive...cov- ering cooperative offshore exploration and eventual pro- duction in southern Kalimantan and northern Sumatra. Japex-Indonesian Limited, for

  10. Education Policy Outlook: Japan

    ERIC Educational Resources Information Center

    Miki, Tadakazu; Pont, Beatriz; Figueroa, Diana Toledo; Peterka, Judith; Fraccola, Sylvain

    2015-01-01

    This policy profile on education in Japan is part of the "Education Policy Outlook" series, which presents comparative analysis of education policies and reforms across the Organisation for Economic Co-operation and Development (OECD) countries. Building on the OECD's substantial comparative and sectorial policy knowledge base, the…

  11. Few smokers in South Auckland access subsidised nicotine replacement therapy.

    PubMed

    Thornley, Simon; Jackson, Gary; McRobbie, Hayden; Sinclair, Siniva; Smith, James

    2010-01-29

    Nicotine replacement therapy (NRT) is a life-saving, cost-effective smoking cessation treatment that doubles the chances of long-term abstinence regardless of the amount of additional support provided. We investigate the proportion of working age people (age 15-64 years) in Counties Manukau District Health Board (CMDHB) who obtained at least one packet of subsidised NRT during 2007, and whether this varied by demographic characteristics. We linked health data in residents of CMDHB aged 15 to 64, using a cross sectional method, to estimate the odds of Maori and Pacific ethnic groups with high smoking prevalence accessing subsidised NRT during 2007 using logistic regression. Demographic variables such as age, gender, other ethnic groups, and socioeconomic deprivation (NZdep) were also included. Subsidised NRT was infrequently (proportion of 'ever users' 0.5%/year, or about 2.1% of smokers) claimed for in CMDHB in 2007. When adjusted for demographic variables, Pacific peoples were 60% less likely to claim NRT than European (odds ratio 0.34; 95%CI 0.29-0.41), despite a higher prevalence of smoking in the former group. An over four-fold increased use of NRT was observed in those aged 55 to 64 years compared to 15 to 25 year olds. Dispensing of NRT is low overall in CMDHB. Lowest rates of treatment were observed in younger age groups, men and Pacific and Maori people. Programmes to increase uptake of such treatment in these groups are urgently needed.

  12. Cortical afferents onto the nucleus Reticularis thalami promote plasticity of low-threshold excitability through GluN2C-NMDARs.

    PubMed

    Fernandez, Laura M J; Pellegrini, Chiara; Vantomme, Gil; Béard, Elidie; Lüthi, Anita; Astori, Simone

    2017-09-25

    Thalamus and cortex represent a highly integrated processing unit that elaborates sensory representations. Interposed between cortex and thalamus, the nucleus Reticularis thalami (nRt) receives strong cortical glutamatergic input and mediates top-down inhibitory feedback to thalamus. Despite growing appreciation that the nRt is integral for thalamocortical functions from sleep to attentional wakefulness, we still face considerable gaps in the synaptic bases for cortico-nRt communication and plastic regulation. Here, we examined modulation of nRt excitability by cortical synaptic drive in Ntsr1-Cre x ChR2 tg/+ mice expressing Channelrhodopsin2 in layer 6 corticothalamic cells. We found that cortico-nRt synapses express a major portion of NMDA receptors containing the GluN2C subunit (GluN2C-NMDARs). Upon repetitive photoactivation (10 Hz trains), GluN2C-NMDARs induced a long-term increase in nRt excitability involving a potentiated recruitment of T-type Ca 2+ channels. In anaesthetized mice, analogous stimulation of cortical afferents onto nRt produced long-lasting changes in cortical local field potentials (LFPs), with delta oscillations being augmented at the expense of slow oscillations. This shift in LFP spectral composition was sensitive to NMDAR blockade in the nRt. Our data reveal a novel mechanism involving plastic modification of synaptically recruited T-type Ca 2+ channels and nRt bursting and indicate a critical role for GluN2C-NMDARs in thalamocortical rhythmogenesis.

  13. Using Open and Interoperable Ways to Publish and Access LANCE AIRS Near-Real Time Data

    NASA Astrophysics Data System (ADS)

    Zhao, P.; Lynnes, C.; Vollmer, B.; Savtchenko, A. K.; Yang, W.

    2011-12-01

    Atmospheric Infrared Sounder (AIRS) Near-Real Time (NRT) data from the Land Atmosphere Near real time Capability for EOS (LANCE) provide the information on the global and regional atmospheric state with very low latency. An open and interoperable platform is useful to facilitate access to and integration of LANCE AIRS NRT data. This paper discusses the use of open-source software components to build Web services for publishing and accessing AIRS NRT data in the context of Service Oriented Architecture (SOA). The AIRS NRT data have also been made available through an OPeNDAP server. OPeNDAP allows several open-source netCDF-based tools such as Integrated Data Viewer, Ferret and Panoply to directly display the Level 2 data over the network. To enable users to locate swath data files in the OPeNDAP server that lie within a certain geographical area, graphical "granule maps" are being added to show the outline of each file on a map of the Earth. The metadata of AIRS NRT data and services is then explored to implement information advertisement and discovery in catalogue systems. Datacasting, an RSS-based technology for accessing Earth Science data and information to facilitate the subscriptions to AIRS NRT data availability, filtering, downloading and viewing data, is also discussed. To provide an easy entry point to AIRS NRT data and services, a Web portal designed for customized data downloading and visualization is introduced.

  14. Japan-Specific Key Regulatory Aspects for Development of New Biopharmaceutical Drug Products.

    PubMed

    Desai, Kashappa Goud; Obayashi, Hirokazu; Colandene, James D; Nesta, Douglas P

    2018-03-28

    Japan represents the third largest pharmaceutical market in the world. Developing a new biopharmaceutical drug product for the Japanese market is a top business priority for global pharmaceutical companies while aligning with ethical drivers to treat more patients in need. Understanding Japan-specific key regulatory requirements is essential to achieve successful approvals. Understanding the full context of Japan-specific regulatory requirements/expectations is challenging to global pharmaceutical companies due to differences in language and culture. This article summarizes key Japan-specific regulatory aspects/requirements/expectations applicable to new drug development, approval, and postapproval phases. Formulation excipients should meet Japan compendial requirements with respect to the type of excipient, excipient grade, and excipient concentration. Preclinical safety assessments needed to support clinical phases I, II, and III development are summarized. Japanese regulatory authorities have taken appropriate steps to consider foreign clinical data, thereby enabling accelerated drug development and approval in Japan. Other important topics summarized in this article include: Japan new drug application-specific bracketing strategies for critical and noncritical aspects of the manufacturing process, regulatory requirements related to stability studies, release specifications and testing methods, standard processes involved in pre and postapproval inspections, management of postapproval changes, and Japan regulatory authority's consultation services available to global pharmaceutical companies. Copyright © 2018 American Pharmacists Association®. Published by Elsevier Inc. All rights reserved.

  15. Risk model of valve surgery in Japan using the Japan Adult Cardiovascular Surgery Database.

    PubMed

    Motomura, Noboru; Miyata, Hiroaki; Tsukihara, Hiroyuki; Takamoto, Shinichi

    2010-11-01

    Risk models of cardiac valve surgery using a large database are useful for improving surgical quality. In order to obtain accurate, high-quality assessments of surgical outcome, each geographic area should maintain its own database. The study aim was to collect Japanese data and to prepare a risk stratification of cardiac valve procedures, using the Japan Adult Cardiovascular Surgery Database (JACVSD). A total of 6562 valve procedure records from 97 participating sites throughout Japan was analyzed, using a data entry form with 255 variables that was sent to the JACVSD office from a web-based data collection system. The statistical model was constructed using multiple logistic regression. Model discrimination was tested using the area under the receiver operating characteristic curve (C-index). The model calibration was tested using the Hosmer-Lemeshow (H-L) test. Among 6562 operated cases, 15% had diabetes mellitus, 5% were urgent, and 12% involved preoperative renal failure. The observed 30-day and operative mortality rates were 2.9% and 4.0%, respectively. Significant variables with high odds ratios included emergent or salvage status (3.83), reoperation (3.43), and left ventricular dysfunction (3.01). The H-L test and C-index values for 30-day mortality were satisfactory (0.44 and 0.80, respectively). The results obtained in Japan were at least as good as those reported elsewhere. The performance of this risk model also matched that of the STS National Adult Cardiac Database and the European Society Database.

  16. Features of standardized nursing terminology sets in Japan.

    PubMed

    Sagara, Kaoru; Abe, Akinori; Ozaku, Hiromi Itoh; Kuwahara, Noriaki; Kogure, Kiyoshi

    2006-01-01

    This paper reports the features and relationships between standardizes nursing terminology sets used in Japan. First, we analyzed the common parts in five standardized nursing terminology sets: the Japan Nursing Practice Standard Master (JNPSM) that includes the names of nursing activities and is built by the Medical Information Center Development Center (MEDIS-DC); the labels of the Japan Classification of Nursing Practice (JCNP), built by the term advisory committee in the Japan Academy of Nursing Science; the labels of the International Classification for Nursing Practice (ICNP) translated to Japanese; the labels, domain names, and class names of the North American Nursing Diagnosis Association (NANDA) Nursing Diagnoses 2003-2004 translated to Japanese; and the terms included in the labels of Nursing Interventions Classification (NIC) translated to Japanese. Then we compared them with terms in a thesaurus dictionary, the Bunrui Goihyo, that contains general Japanese words and is built by the National Institute for Japanese Language. 1) the level of interchangeability between four standardized nursing terminology sets is quite low; 2) abbreviations and katakana words are frequently used to express nursing activities; 3) general Japanese words are usually used to express the status or situation of patients.

  17. Employment in Contemporary Japan.

    ERIC Educational Resources Information Center

    Dillon, Ken; And Others

    This paper presents guidelines and suggestions for non-Japanese English-as-a-Second-Language teachers seeking employment in Japan. The first section outlines the educational qualifications needed to teach in language schools, secondary schools, and higher education institutions, and notes common employment patterns and the timing required to make…

  18. Political Corruption in Japan.

    ERIC Educational Resources Information Center

    Reed, Steven R.; And Others

    1996-01-01

    Provides an overview of political corruption and its place in Japanese culture and society. Discusses recent scandals and efforts at political reform. These efforts are moving Japan from a "boss-patronage" system to a "civic-culture." Includes a table of post-war Japanese prime ministers and corruption scandals. (MJP)

  19. Current trends in rehabilitation engineering in Japan.

    PubMed

    Ohnabe, Hisaichi

    2006-01-01

    In 2005, the elderly generation comprised 20% of the Japanese population. This percentage will grow to approximately 30% in 2030, meaning that nearly one in three people in Japan will be 65 years of age or older. Japan is the first nation in the world to face this situation. This article uses the context of Japanese society to give an overview of the elderly and people with disabilities; the International Classification of Functioning, Disability, and Health model; rehabilitation engineering-related policy; and education. In addition, we examine how governmental programs and Japanese law regarding technical aids may evolve by 2030. Partner robots, intelligent powered wheelchairs, nursing robots, and other technologies are introduced as examples of rehabilitation engineering and assistive technology. We also discuss the volunteer activities of the Rehabilitation Engineering Society of Japan (RESJA) in response to the Asian tsunami disaster and the achievements of a group of students from a Japanese senior high school of industry.

  20. The Annual Cycle of the Japan Sea Throughflow

    NASA Astrophysics Data System (ADS)

    Kida, S.; Qiu, B.; Yang, J.; Lin, X.

    2016-02-01

    The mechanism responsible for the annual cycle of the flows through the straits of Japan Sea is investigated using a two-layer model. Japan Sea is one of the marginal sea located in the western North Pacific that is separated from the Pacific by the islands of Japan. Three narrow and shallow straits, the Tsushima, Tsugaru, and Soya Straits, connect this sea towards the Pacific Ocean and Okhotsk Sea and observations show that the flow through these three straits vary annually with a maximum transport in summer-fall and a minimum transport in winter. The variability is large for Soya (north) and Tsushima (south) Straits but weak for the Tsugaru Strait (middle). We find the subpolar winds located to the north of Soya Strait to be the primary forcing agent of this annual cycle rather than the subtropical winds located to the east of Japan. The subpolar winds generate baroclinic Kelvin waves that perturb the sea surface height at the Soya Strait, cause barotropic adjustment to occur within the Japan Sea, and change the flow at the other straits. The shallow topography at the straits plays an important role. This mechanism explains why the annual cycle at the three straits occur almost synchronously. We also find the around-island integral constraint a useful tool for explaining how the magnitude of the annual cycle at the three straits are controlled. The theorem show the magnitude and direction of the flow controlled largely by the ratio of the meridional length of the two islands that is bounded by the three straits..

  1. Review of mental-health-related stigma in Japan.

    PubMed

    Ando, Shuntaro; Yamaguchi, Sosei; Aoki, Yuta; Thornicroft, Graham

    2013-11-01

    The aim of this study is to understand the nature and characteristics of mental-health-related stigma among Japanese people. We searched relevant studies in English or Japanese published since 2001 using MEDLINE and PsycINFO, and found 19 studies that examined mental-health-related stigma in Japan. Regarding knowledge about mental illness, reviewed studies showed that in the Japanese general population, few people think that people can recover from mental disorders. Psychosocial factors, including weakness of personality, are often considered the cause of mental illness, rather than biological factors. In addition, the majority of the general public in Japan keep a greater social distance from individuals with mental illness, especially in close personal relationships. Schizophrenia is more stigmatized than depression, and its severity increases the stigmatizing attitude toward mental illness. The literature also showed an association between more direct social contact between health professionals and individuals with mental illness and less stigmatization by these professionals. Less stigmatization by mental health professionals may be associated with accumulation of clinical experience and daily contact with people who have mental illness. Stigmatizing attitudes in Japan are stronger than in Taiwan or Australia, possibly due to institutionalism, lack of national campaigns to tackle stigma, and/or society's valuing of conformity in Japan. Although educational programs appear to be effective in reducing mental-health-related stigma, future programs in Japan need to address problems regarding institutionalism and offer direct social contact with people with mental illness. © 2013 The Authors. Psychiatry and Clinical Neurosciences © 2013 Japanese Society of Psychiatry and Neurology.

  2. Japan's Democracy: How Much Change? Headline Series No. 305.

    ERIC Educational Resources Information Center

    Krauss, Ellis S.

    This booklet analyzes the changes that have occurred in Japan in the postwar period. The book is divided into four chapters. Chapter 1, "Revolutionary Change: American Occupation, 1945-52," focuses on the dramatic changes brought by Occupation forces. Chapter 2, "Evolutionary Change: Japan's Democracy from the Occupation through the…

  3. Career Education in Japan: Its Current Status and Condition.

    ERIC Educational Resources Information Center

    Senzaki, Takeshi

    1993-01-01

    Presents framework of changing status of career education in Japan, describing history of career education in that country. Includes chronology of career education in Japan since 1960. Notes that, in future, Japanese career education and guidance programs must bridge gaps between academics and employment, education and occupations, school and…

  4. Koreans in Japan: Their Influence on Korean-Japanese Relations.

    DTIC Science & Technology

    1979-09-01

    1963. 31. The Republic of Korea National Red Cross, The Dispersed Families in Korea, Seoul, 1977. 32. Sato , Shoki, Koreans in Japan - The...1975. 34. Sumiya, Mikio , Kankoku no Keizai (The Korean Economy), Iwanami Shoten, Tokyo, Japan, 1974. 35. U.S. Government Printing Office, U.S. Army Area

  5. Suicide prevention strategies in Japan: a 15-year review (1998-2013).

    PubMed

    Takeshima, Tadashi; Yamauchi, Takashi; Inagaki, Masatoshi; Kodaka, Manami; Matsumoto, Toshihiko; Kawano, Kenji; Katsumata, Yotaro; Fujimori, Maiko; Hisanaga, Ayaka; Takahashi, Yoshitomo

    2015-02-01

    Suicide is a global public health problem and solutions to it can be found only through a global dialog. The suicide rate in Japan has been alarming, but Japan has made substantial efforts to reduce this rate, making prevention a high priority. This report reviews the developmental stages of a comprehensive policy of suicide prevention in Japan from 1998 to 2013. Our review suggests that suicide prevention activities were facilitated by the 2006 Basic Act for Suicide Prevention and the 2007 General Principles of Suicide Prevention Policy. Along with the establishment of a Special Fund program for local governments, the Basic Act and General Principles led to the development of a comprehensive and multi-sector approach to suicide prevention. Suicide rates in Japan, especially among middle-aged men, decreased consistently after 2009, suggesting that the initiatives were effective. Continuous monitoring is needed to evaluate Japan's suicide prevention policy.

  6. Liver transplantation in Japan.

    PubMed

    Soyama, Akihiko; Eguchi, Susumu; Egawa, Hiroto

    2016-10-01

    As of December 31, 2014, 7937 liver transplants (7673 living donor transplants and 264 deceased donor liver transplantations [DDLTs; 261 from heart-beating donors and 3 from non-heart-beating donors]) have been performed in 67 institutions in Japan. The revised Organ Transplant Law in Japan came into effect in July 2010, which allows organ procurement from brain-dead individuals, including children, with family consent if the patient had not previously refused organ donation. However, the number of deceased donor organ donations has not increased as anticipated. The rate of deceased organ donations per million population (pmp) has remained at less than 1. To maximize the viability of the limited numbers of donated organs, a system has been adopted that includes the partnership of well-trained transplant consultant doctors and local doctors. For compensating for the decreased opportunity of on-site training, an educational system regarding quality organ procurement for transplant surgeons has also been established. Furthermore, experts in the field of liver transplantation are currently discussing adoption of the Model for End-Stage Liver Disease score for allocation, promoting split-liver transplantation, arranging in-house coordinators, and improving the frequency of proposing the option to donate organs to the families. To overcome the shortage of donors during efforts to promote organ donation, living donor liver transplantation (LDLT) has been developed in Japan. Continuous efforts to increase DDLT in addition to the successful experience of LDLT will increase the benefits of liver transplantation for more patients. Liver Transplantation 22 1401-1407 2016 AASLD. © 2016 by the American Association for the Study of Liver Diseases.

  7. Historical Change of Equilibrium Water Temperature in Japan

    NASA Astrophysics Data System (ADS)

    Miyamoto, H.

    2015-12-01

    Changes in freshwater ecosystems due to a climate change have been great concern for sustainable river basin management both for water resources utilization and ecological conservation. However, their impact seems to be difficult to evaluate because of wide variety of basin characteristics along a river network both in nature and social environment. This presentation uses equilibrium water temperature as a simple criterion index for evaluating the long-term changes of stream thermal environment due to the historical climate change in Japan. It examines, at first, the relationship between the equilibrium water temperature and the stream temperature observed for 7 years at a lower reach in the Ibo River, Japan. It analyzes, then, the seasonal and regional trends of the equilibrium water temperature change for the last 50 years at 133 meteorological station sites throughout Japan, discussing their rising or falling characteristics. The correlation analysis at the local reach of the Ibo River shows that the equilibrium water temperature has similar trend of change as the stream temperature. However, its value tends to be higher than the stream temperature in summer, while lower in winter. The onset of the higher equilibrium water temperature fluctuates annually from mid February to early April. This onset fluctuation at each spring could be influenced by the different amount of snow at the antecedent winter. The rising or falling trends of the equilibrium water temperature are analyzed both annually and seasonally through the regression analysis of the 133 sites in Japan. Consequently, the trends of the temperature change could be categorized by 12 patterns. As for the seasonal analysis, the results shows that there are many sites indicating the falling trend in spring and summer, and rising trends in autumn and winter. In particular, winter has the strong rising tendency throughout Japan. As for the regional analysis, the result illustrates the precise rationality; e

  8. Hypnotherapy is more effective than nicotine replacement therapy for smoking cessation: results of a randomized controlled trial.

    PubMed

    Hasan, Faysal M; Zagarins, Sofija E; Pischke, Karen M; Saiyed, Shamila; Bettencourt, Ann Marie; Beal, Laura; Macys, Diane; Aurora, Sanjay; McCleary, Nancy

    2014-02-01

    The efficacy of pharmacotherapy for smoking cessation is well documented. However, due to relapse rates and side effects, hypnotherapy is gaining attention as an alternative treatment option. The aim of this one-center randomized study was to compare the efficacy of hypnotherapy alone, as well as hypnotherapy with nicotine replacement therapy (NRT), to conventional NRT in patients hospitalized with a cardiac or pulmonary illness. We evaluated self-reported and biochemically verified 7-day prevalence smoking abstinence rates at 12 and 26 weeks post-hospitalization. Patients (n=164) were randomized into one of three counseling-based treatment groups: NRT for 30 days (NRT; n=41), a 90-min hypnotherapy session (H; n=39), and NRT with hypnotherapy (HNRT; n=37). Treatment groups were compared to a "self-quit" group of 35 patients who refused intervention. Hypnotherapy patients were more likely than NRT patients to be nonsmokers at 12 weeks (43.9% vs. 28.2%; p=0.14) and 26 weeks after hospitalization (36.6% vs. 18.0%; p=0.06). Smoking abstinence rates in the HNRT group were similar to the H group. There was no difference in smoking abstinence rates at 26 weeks between "self quit" and participants in any of the treatment groups. In multivariable regression analysis adjusting for diagnosis and demographic characteristics, H and HNRT were over three times more likely than NRT participants to abstain at 26-weeks post-discharge (RR=3.6; p=0.03 and RR=3.2; p=0.04, respectively). Hypnotherapy is more effective than NRT in improving smoking abstinence in patients hospitalized for a smoking-related illness, and could be an asset to post-discharge smoking cessation programs. Copyright © 2014 Elsevier Ltd. All rights reserved.

  9. Cost-Effectiveness of Nicotine Patches for Smoking Cessation in Pregnancy: A Placebo Randomized Controlled Trial (SNAP).

    PubMed

    Essex, Holly N; Parrott, Steve; Wu, Qi; Li, Jinshuo; Cooper, Sue; Coleman, Tim

    2015-06-01

    Smoking during pregnancy is the most important, preventable cause of adverse pregnancy outcomes including miscarriage, premature birth, and low birth weight with huge financial costs to the National Health Service. However, there are very few published economic evaluations of smoking cessation interventions in pregnancy and previous studies are predominantly U.S.-based and do not present incremental cost-effectiveness ratios (ICER). A number of studies have demonstrated cost-effectiveness of nicotine replacement therapy (NRT) in the general population, but this has yet to be tested among pregnant smokers. A cost-effectiveness analysis was undertaken alongside the smoking, nicotine, and pregnancy trial to compare NRT patches plus behavioral support to behavioral support alone, for pregnant women who smoked. At delivery, biochemically verified quit rates were slightly higher at 9.4% in the NRT group compared to 7.6% in the control group (odds ratio = 1.26, 95% CI = 0.82-1.96), at an increased cost of around £90 per participant. Higher costs in the NRT group were mainly attributable to the cost of NRT patches (mean = £46.07). The incremental cost-effectiveness ratio associated with NRT was £4,926 per quitter and a sensitivity analysis including only singleton births yielded an ICER of £4,156 per quitter. However, wide confidence intervals indicated a high level of uncertainty. Without a specific willingness to pay threshold, and due to high levels of statistical uncertainty, it is hard to determine the cost-effectiveness of NRT in this population. Furthermore, future research should address compliance issues, as these may dilute any potential effects of NRT, thus reducing the cost-effectiveness. © The Author 2014. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  10. Predictors of Adherence to Nicotine Replacement Therapy (Nicotine Patch) Among Homeless Persons Enrolled in a Randomized Controlled Trial Targeting Smoking Cessation.

    PubMed

    Ojo-Fati, O; Thomas, J L; Vogel, R I; Ogedegbe, O; Jean-Louis, G; Okuyemi, K S

    2016-01-01

    Adherence to smoking cessation treatment is generally low, especially among socio-economically disadvantaged groups including individuals experiencing homelessness and those with mental illnesses. Despite the high smoking rates in homeless populations (~70%) no study to date has systematically examined predictors of adherence to nicotine replacement therapy (NRT) in this population. The aim of this secondary analysis was to identify predictors of adherence to NRT in a smoking cessation trial conducted among homeless smokers. Secondary analysis of data from a randomized controlled trial enrolling 430 persons who were homeless and current cigarette smokers. Participants were assigned to one of the two study conditions to enhance smoking cessation: Motivational Interviewing (MI; 6 sessions of MI + 8 weeks of NRT) or Standard Care (Brief advice to quit+ 8 weeks of NRT). The primary outcome for the current analysis was adherence to NRT at end of treatment (8 weeks following randomization). Adherence was defined as a total score of zero on a modified Morisky adherence scale). Demographic and baseline psychosocial, tobacco-related, and substance abuse measures were compared between those who did and did not adhere to NRT. After adjusting for confounders, smokers who were depressed at baseline (OR=0.58, 95% CI, 0.38-0.87, p=0.01), had lower confidence to quit (OR=1.10, 95% CI, 1.01-1.19, p=0.04), were less motivated to adhere (OR=1.04, 95% CI, 1.00-1.07, p=0.04), and were less likely to be adherent to NRT. Further, age of initial smoking was positively associated with adherence status (OR= 0.83, 95% CI, 0.69-0.99, p=0.04). These results suggest that smoking cessation programs conducted in this population may target increased adherence to NRT by addressing both depression and motivation to quit. clinicaltrials.gov: NCT00786149.

  11. Current Indoor Air Quality in Japan.

    PubMed

    Jinno, Hideto

    2016-01-01

    People spend more than two thirds of their daily time indoors. Hence, maintaining a healthy indoor environment is indispensable for the prevention of building related illness. In Japan, guidelines for indoor air quality have been established for 13 volatile/semi-volatile organic compounds (VOCs/SVOCs). These guidelines are now under revision by the Committee on Sick House Syndrome: Indoor Air Pollution. In order to gain information on the current indoor air pollutants and their levels, we carried out a nation-wide survey of VOCs and aldehydes in indoor residential air during 2012-2013. In this review, I concisely summarized the current indoor air quality of Japan.

  12. Attitudes toward the Homeless: A U.S.-Japan Comparison.

    ERIC Educational Resources Information Center

    Guzewicz, Tony D.; Takooshian, Harold

    1993-01-01

    Compares attitudes toward the homeless in Japan and the United States through a survey of 268 Japanese and 254 U.S. adults and adolescents interviewed in public places. In Japan, homelessness is seldom discussed, and poverty, which may be as widespread as in the United States, is often not recognized. (SLD)

  13. Japan's Teacher Acculturation: Critical Analysis through Comparative Ethnographic Narrative

    ERIC Educational Resources Information Center

    Howe, Edward R.

    2005-01-01

    Cross-cultural teaching and research in Canada and Japan is reported. Ethnographic narrative methods were used to examine Japan's teacher acculturation. Canada's teachers are largely required to work in isolation, to learn their practice through trial and error. There is little provision for mentorship and insufficient time to reflect. In…

  14. Tokugawa Japan and Industrial Revolution Britain: Two Misunderstood Societies

    ERIC Educational Resources Information Center

    Ellington, Lucien

    2013-01-01

    In this article, the author presents a truer picture than economic historians have previously had of the economies of Tokugawa Japan, and Britain during the Industrial Revolution. Though substantially different, both societies were prosperous compared to most of the rest of the world. Japan's economic success began in the Tokugawa period…

  15. Recycling scheme for scrapped automobiles in Japan

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Suzuki, Masao; Nakajima, Akira; Taya, Sadao

    Over 5 million cars are scrapped yearly in Japan. After dismantling scrapped automobiles, they are put into a shredder for differential recovery of ferrous and nonferrous metals. The residue, which is called shredder dust, runs over 1.2 million tons per year. This paper reports a entire sequence of scrapping cars in Japan with the following sections: (1) production and scrapped car management, (2) material composition, (3) dismantling, (4) shredder plant, (5) differential recovery of metals including specific gravity and newly developed color separation.

  16. Japan's Eco-School Programme

    ERIC Educational Resources Information Center

    Mori, Masayuki

    2007-01-01

    Since 1997, several ministries in Japan have collaborated on an eco-school programme, which applies to both newly constructed and renovated school buildings, in an effort to make its schools more environmentally friendly. The programme equips school buildings with ecological features such as photovoltaic cells, solar thermal collectors, other new…

  17. An immediate effect of axial neck rotation training with real time visual feedback using a smartphone inclinometer on improvement in axial neck rotation function.

    PubMed

    Park, Kyue-Nam; Kwon, Oh-Yun; Kim, Si-Hyun; Jeon, In-Cheol

    2017-03-01

    The purpose of this study was to compare the immediate effects of axial neck rotation training (Axi-NRT) with and without real-time visual feedback (VF) using a smartphone inclinometer on the range of motion (ROM) for axial neck rotation and the onset of compensatory neck lateral bending and extension during active neck rotation. Twenty participants with restricted ROM for neck rotation but no neck pain (21.1 ± 1.6 years and 8 males, 12 females) were recruited for Axi-NRT with VF, and twenty age- and gender-matched participants with restricted ROM for neck rotation were recruited for Axi-NRT without VF. Changes in ROM for neck rotation and the onset time of compensatory neck movement during active neck rotation were measured using an electromagnetic tracking system. Axi-NRT with VF was more effective in increasing ROM for neck rotation and decreasing and delaying the onset of compensatory neck movements during active neck rotation compared with Axi-NRT without VF. Repeated Axi-NRT using VF is useful to educate participants in maintaining the axis of the cervical spine and to increase ROM for axial neck rotation with less compensatory neck motion in participants with a restricted range of neck rotations.

  18. U.S. Military Aviation Mishaps In Japan and Okinawan Political Controversy

    DTIC Science & Technology

    2015-12-01

    political controversy over U.S. bases in Japan, the American presence in the island country has proven its strategic advantages for the United States...CONTEMPORARY OKINAWAN HISTORY Located approximately 400 miles south of mainland Japan, Okinawa is the largest island in the Ryukyu Island chain. In the 17th...century, Okinawa served as tributary state to both China and Japan. Commerce brought additional influences to the island , helping to shape a

  19. Political economy of tobacco control policy on public health in Japan.

    PubMed

    Desapriya, E B R; Iwase, Nobutada; Shimizu, Shinji

    2003-02-01

    Tobacco use, particularly smoking, remains the number one cause of preventable disease and mortality in Japan. This review of the tobacco control policy and public health is the first to offer a composite review of the subject within Japan. This review attempts to evaluate the most important aspects of the current political economy of the tobacco control policy, and concludes that more effective control policies must be employed to minimize the impact of smoking on the public's health in Japan. Further the article attempts to place the approaches in the larger context of tobacco control, providing a vision for the future of tobacco prevention and control based on current knowledge. Tobacco use will remain the leading cause of preventable illness and death in Japan, until tobacco prevention and control efforts are commensurate with the harm caused by tobacco. Taken together, the results of various studies have clearly shown that control measures can influence tobacco smoking patterns, and in turn, the rate of tobacco-related problems. Government tobacco taxes have not kept pace with inflation for years. Availability of tobacco is virtually unlimited with easy access and the prices being very low due to the strong currency of Japan. Thus Japan must be one of the most tobacco accessible countries. It is important to ensure that people are not conditioned to smoke tobacco by an unduly favourable economic and commercial environment. For that reason, prevention advocates have called for substantial regulation of tobacco products and appeal for both tobacco tax increases and tobacco taxes to be indexed to inflation. In this review, present tobacco related public health policies in Japan are discussed with implication for prevention of tobacco related problems. Continued research in this area will be necessary to determine the most effective policies of reducing tobacco related problems in Japan.

  20. Genetic differentiation of methicillin-resistant Staphylococcus aureus strains from Korea and Japan.

    PubMed

    Soo Ko, Kwan; Peck, Kyong Ran; Sup Oh, Won; Lee, Nam Yong; Hiramatsu, Keiichi; Song, Jae-Hoon

    2005-01-01

    In this study, we evaluated genetic differentiation between methicillin-resistant Staphylococcus aureus (MRSA) strains from Korea and Japan. Seventy-five MRSA strains, including 25 h VISA strains, were analyzed by molecular typing methods, including multilocus sequence typing (MLST), SCC mec typing, and spa typing. The most prevalent genotype of MRSA strains, in both Korea and Japan, was ST 5-MRSA-II with the DMGMK spa motif, characteristic of the New York/Japan MRSA clone. In spite of these common features in MRSA strains from Korea and Japan, we also observed some genotypic divergence in MRSA from the two countries. Several spa types might be differentiated from a prevalent prototype (TJMBMDMGMK) that is shared by the two countries, revealing a unique geographic distribution. SCC mec type II lacking pUB110, designated type IIA, was found more frequently in Korea than in Japan. The rate of gentamicin resistance was also dramatically different between the two countries: 87.2% (Korea) vs. 28.6% (Japan). These preliminary findings suggested that MRSA strains from Korea and Japan might have originated from a common ancestor, but then clearly differentiated according to locality. A further comprehensive study should be performed to document the hypotheses from this study.

  1. PREFACE: India-Japan Workshop on Biomolecular Electronics & Organic Nanotechnology for Environment Preservation

    NASA Astrophysics Data System (ADS)

    Onoda, Mitsuyoshi; Malhotra, Bansi D.

    2012-04-01

    The 'India-Japan Workshop on Biomolecular Electronics & Organic Nanotechnology for Environment Preservation' (IJWBME 2011) will be held on 7-10 December 2011 at EGRET Himeji, Himeji, Hyogo, Japan. This workshop was held for the first time on 17-19 December 2009 at NPL, New Delhi. Keeping in mind the importance of organic nanotechnology and biomolecular electronics for environmental preservation and their anticipated impact on the economics of both the developing and the developed world, IJWBME 2009 was jointly organized by the Department of Biological Functions, Graduate School of Life Sciences and Systems Engineering, the Kyushu Institute of Technology (KIT), Kitakyushu, Japan, and the Department of Science & Technology Centre on Biomolecular Electronics (DSTCBE), National Physical Laboratory (NPL). Much progress in the field of biomolecular electronics and organic nanotechnology for environmental preservation is expected for the 21st Century. Organic optoelectronic devices, such as organic electroluminescent devices, organic thin-film transistors, organic sensors, biological systems and so on have especially attracted much attention. The main purpose of this workshop is to provide an opportunity for researchers interested in biomolecular electronics and organic nanotechnology for environmental preservation, to come together in an informal and friendly atmosphere and exchange technical knowledge and experience. We are sure that this workshop will be very useful and fruitful for all participants in summarizing the recent progress in biomolecular electronics and organic nanotechnology for environmental preservation and preparing new ground for the next generation. Many papers have been submitted from India and Japan and more than 30 papers have been accepted for presentation. The main topics of interest are as follows: Bioelectronics Biomolecular Electronics Fabrication Techniques Self-assembled Monolayers Nano-sensors Environmental Monitoring Organic Devices

  2. Digital Technology at the National Science Museum of Japan

    ERIC Educational Resources Information Center

    Lydens, Lois; Saito, Yasuji; Inoue, Tohru

    2007-01-01

    The National Science Museum (NSM) in Japan has recently completed a project using different types of visitor-oriented digital technologies. With sponsorship from the Japan Society for the Promotion of Science (JSPS), the NSM team carried out a four-year study to examine how digital technologies can be used to enhance as well as educationally…

  3. Ethics Education for Professionals in Japan: A Critical Review

    ERIC Educational Resources Information Center

    Maruyama, Yasushi; Ueno, Tetsu

    2010-01-01

    Ethics education for professionals has become popular in Japan over the last two decades. Many professional schools now require students to take an applied ethics or professional ethics course. In contrast, very few courses of professional ethics for teaching exist or have been taught in Japan. In order to obtain suggestions for teacher education,…

  4. Ideas for Integrating Japan into the Curriculum. ERIC Digest.

    ERIC Educational Resources Information Center

    Wojtan, Linda S.

    This ERIC Digest discusses how, by studying Japan, the larger context of the Asia-Pacific region can be explored and students can be introduced to current realities. The top 5 competitive countries for 1994 were the United States, Singapore, Japan, Hong Kong, and Germany. Because of the increasing interdependence between the United States and…

  5. Textbook Development and Selection in Japan and the United States.

    ERIC Educational Resources Information Center

    Tani, Masaru; And Others

    1993-01-01

    Reports on a study trip by 13 U.S. social studies educators and publishers to Japan. Compares development, marketing, and selection of textbooks in the United States and Japan. Concludes that both nations should improve textbooks and textbook selection processes. (CFR)

  6. Current status of pregnancy-related maternal mortality in Japan: a report from the Maternal Death Exploratory Committee in Japan.

    PubMed

    Hasegawa, Junichi; Sekizawa, Akihiko; Tanaka, Hiroaki; Katsuragi, Shinji; Osato, Kazuhiro; Murakoshi, Takeshi; Nakata, Masahiko; Nakamura, Masamitsu; Yoshimatsu, Jun; Sadahiro, Tomohito; Kanayama, Naohiro; Ishiwata, Isamu; Kinoshita, Katsuyuki; Ikeda, Tomoaki

    2016-03-21

    To clarify the problems related to maternal deaths in Japan, including the diseases themselves, causes, treatments and the hospital or regional systems. Descriptive study. Maternal death registration system established by the Japan Association of Obstetricians and Gynecologists (JAOG). Women who died during pregnancy or within a year after delivery, from 2010 to 2014, throughout Japan (N=213). The preventability and problems in each maternal death. Maternal deaths were frequently caused by obstetric haemorrhage (23%), brain disease (16%), amniotic fluid embolism (12%), cardiovascular disease (8%) and pulmonary disease (8%). The Committee considered that it was impossible to prevent death in 51% of the cases, whereas they considered prevention in 26%, 15% and 7% of the cases to be slightly, moderately and highly possible, respectively. It was difficult to prevent maternal deaths due to amniotic fluid embolism and brain disease. In contrast, half of the deaths due to obstetric haemorrhage were considered preventable, because the peak duration between the initial symptoms and initial cardiopulmonary arrest was 1-3 h. A range of measures, including individual education and the construction of good relationships among regional hospitals, should be established in the near future, to improve primary care for patients with maternal haemorrhage and to save the lives of mothers in Japan. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  7. Enemies into Allies: American Stability Operations and the Transformation of Japan 1945-1952

    DTIC Science & Technology

    2011-05-19

    on Japanese forces in Manchuria finally shattered the last hopes of Emperor Hirohito and Japan’s governmental leadership.7 Jun Eto suggested that...of Modern Japan (New York: HarperCollins Publishers, 2000), 511. 8 Jun Eto , A Nation Reborn – A Short History of Postwar Japan (Tokyo: International...Modern Japan, trans. Mikiso Hane and John K . Urda (New York: Free Press, 1995), 39. First- 17 Brian J. McVeigh, Nationalisms of Japan – Managing and

  8. Big mantle wedge, anisotropy, slabs and earthquakes beneath the Japan Sea

    NASA Astrophysics Data System (ADS)

    Zhao, Dapeng

    2017-09-01

    The Japan Sea is a part of the western Pacific trench-arc-backarc system and has a complex bathymetry and intense seismic activities in the crust and upper mantle. Local seismic tomography revealed strong lateral heterogeneities in the crust and uppermost mantle beneath the eastern margin of the Japan Sea, which was determined using P and S wave arrival times of suboceanic earthquakes relocated precisely with sP depth phases. Ambient-noise tomography revealed a thin crust and a thin lithosphere beneath the Japan Sea and significant low-velocity (low-V) anomalies in the shallow mantle beneath the western and eastern margins of the Japan Sea. Observations with ocean-bottom seismometers and electromagnetometers revealed low-V and high-conductivity anomalies at depths of 200-300 km in the big mantle wedge (BMW) above the subducting Pacific slab, and the anomalies are connected with the low-V zone in the normal mantle wedge beneath NE Japan, suggesting that both shallow and deep slab dehydrations occur and contribute to the arc and back-arc magmatism. The Pacific slab has a simple geometry beneath the Japan Sea, and earthquakes occur actively in the slab down to a depth of ∼600 km beneath the NE Asian margin. Teleseismic P and S wave tomography has revealed that the Philippine Sea plate has subducted aseismically down to the mantle transition zone (MTZ, 410-660 km) depths beneath the southern Japan Sea and the Tsushima Strait, and a slab window is revealed within the aseismic Philippine Sea slab. Seismic anisotropy tomography revealed a NW-SE fast-velocity direction in the BMW, which reflects corner flows induced by the fast deep subduction of the Pacific slab. Large deep earthquakes (M > 7.0; depth > 500 km) occur frequently beneath the Japan Sea western margin, which may be related to the formation of the Changbai and Ulleung intraplate volcanoes. A metastable olivine wedge is revealed within the cold core of the Pacific slab at the MTZ depth, which may be related

  9. A Hybrid Tsunami Risk Model for Japan

    NASA Astrophysics Data System (ADS)

    Haseemkunju, A. V.; Smith, D. F.; Khater, M.; Khemici, O.; Betov, B.; Scott, J.

    2014-12-01

    Around the margins of the Pacific Ocean, denser oceanic plates slipping under continental plates cause subduction earthquakes generating large tsunami waves. The subducting Pacific and Philippine Sea plates create damaging interplate earthquakes followed by huge tsunami waves. It was a rupture of the Japan Trench subduction zone (JTSZ) and the resultant M9.0 Tohoku-Oki earthquake that caused the unprecedented tsunami along the Pacific coast of Japan on March 11, 2011. EQECAT's Japan Earthquake model is a fully probabilistic model which includes a seismo-tectonic model describing the geometries, magnitudes, and frequencies of all potential earthquake events; a ground motion model; and a tsunami model. Within the much larger set of all modeled earthquake events, fault rupture parameters for about 24000 stochastic and 25 historical tsunamigenic earthquake events are defined to simulate tsunami footprints using the numerical tsunami model COMCOT. A hybrid approach using COMCOT simulated tsunami waves is used to generate inundation footprints, including the impact of tides and flood defenses. Modeled tsunami waves of major historical events are validated against observed data. Modeled tsunami flood depths on 30 m grids together with tsunami vulnerability and financial models are then used to estimate insured loss in Japan from the 2011 tsunami. The primary direct report of damage from the 2011 tsunami is in terms of the number of buildings damaged by municipality in the tsunami affected area. Modeled loss in Japan from the 2011 tsunami is proportional to the number of buildings damaged. A 1000-year return period map of tsunami waves shows high hazard along the west coast of southern Honshu, on the Pacific coast of Shikoku, and on the east coast of Kyushu, primarily associated with major earthquake events on the Nankai Trough subduction zone (NTSZ). The highest tsunami hazard of more than 20m is seen on the Sanriku coast in northern Honshu, associated with the JTSZ.

  10. Glucose Elevates NITRATE TRANSPORTER2.1 Protein Levels and Nitrate Transport Activity Independently of Its HEXOKINASE1-Mediated Stimulation of NITRATE TRANSPORTER2.1 Expression1[W][OPEN

    PubMed Central

    de Jong, Femke; Thodey, Kate; Lejay, Laurence V.; Bevan, Michael W.

    2014-01-01

    Mineral nutrient uptake and assimilation is closely coordinated with the production of photosynthate to supply nutrients for growth. In Arabidopsis (Arabidopsis thaliana), nitrate uptake from the soil is mediated by genes encoding high- and low-affinity transporters that are transcriptionally regulated by both nitrate and photosynthate availability. In this study, we have studied the interactions of nitrate and glucose (Glc) on gene expression, nitrate transport, and growth using glucose-insensitive2-1 (gin2-1), which is defective in sugar responses. We confirm and extend previous work by showing that HEXOKINASE1-mediated oxidative pentose phosphate pathway (OPPP) metabolism is required for Glc-mediated NITRATE TRANSPORTER2.1 (NRT2.1) expression. Treatment with pyruvate and shikimate, two products derived from intermediates of the OPPP that are destined for amino acid production, restores wild-type levels of NRT2.1 expression, suggesting that metabolites derived from OPPP metabolism can, together with Glc, directly stimulate high levels of NRT2.1 expression. Nitrate-mediated NRT2.1 expression is not influenced by gin2-1, showing that Glc does not influence NRT2.1 expression through nitrate-mediated mechanisms. We also show that Glc stimulates NRT2.1 protein levels and transport activity independently of its HEXOKINASE1-mediated stimulation of NRT2.1 expression, demonstrating another possible posttranscriptional mechanism influencing nitrate uptake. In gin2-1 plants, nitrate-responsive biomass growth was strongly reduced, showing that the supply of OPPP metabolites is essential for assimilating nitrate for growth. PMID:24272701

  11. Development of an interprofessional competency framework in Japan.

    PubMed

    Haruta, Junji; Sakai, Ikuko; Otsuka, Mariko; Yoshimoto, Hisashi; Yoshida, Kazue; Goto, Michiko; Shimoi, Toshinori

    2016-09-01

    This article presents a project that aimed to identify a set of competencies (domains and statements) to prepare Japanese students and healthcare practitioners for collaborative practice. The Japan Association for Interprofessional Education (JAIPE) has started a government-funded project to formulate its interprofessional competency framework, in cooperation with professional organisations (e.g. Japan Society for Medical Education) in healthcare and social sciences. This three-year project is underway as part of the Initiative to Build up the Core Healthcare Personnel programme of Mie University. This project consists of five stages: literature review, data collection, prototype development, consensus formation, and finalisation. Our efforts will culminate in Japan's first interprofessional competency framework, with consensus from relevant academic societies and other stakeholders. We hope that the involvement of stakeholder participation will improve the usability of the final interprofessional competency framework.

  12. The SNAP trial: a randomised placebo-controlled trial of nicotine replacement therapy in pregnancy--clinical effectiveness and safety until 2 years after delivery, with economic evaluation.

    PubMed

    Cooper, Sue; Lewis, Sarah; Thornton, James G; Marlow, Neil; Watts, Kim; Britton, John; Grainge, Matthew J; Taggar, Jaspal; Essex, Holly; Parrott, Steve; Dickinson, Anne; Whitemore, Rachel; Coleman, Tim

    2014-08-01

    Smoking during pregnancy causes many adverse pregnancy and birth outcomes. Nicotine replacement therapy (NRT) is effective for cessation outside pregnancy but efficacy and safety in pregnancy are unknown. We hypothesised that NRT would increase smoking cessation in pregnancy without adversely affecting infants. To compare (1) at delivery, the clinical effectiveness and cost-effectiveness for achieving biochemically validated smoking cessation of NRT patches with placebo patches in pregnancy and (2) in infants at 2 years of age, the effects of maternal NRT patch use with placebo patch use in pregnancy on behaviour, development and disability. Randomised, placebo-controlled, parallel-group trial and economic evaluation with follow-up at 4 weeks after randomisation, delivery and until infants were 2 years old. Randomisation was stratified by centre and a computer-generated sequence was used to allocate participants using a 1 : 1 ratio. Participants, site pharmacies and all study staff were blind to treatment allocation. Seven antenatal hospitals in the Midlands and north-west England. Women between 12 and 24 weeks' gestation who smoked ≥ 10 cigarettes a day before and ≥ 5 during pregnancy, with an exhaled carbon monoxide (CO) reading of ≥ 8 parts per million (p.p.m.). NRT patches (15 mg per 16 hours) or matched placebo as an 8-week course issued in two equal batches. A second batch was dispensed at 4 weeks to those abstinent from smoking. self-reported, prolonged abstinence from smoking between a quit date and childbirth, validated at delivery by CO measurement and/or salivary cotinine (COT) (primary outcome). Infants, at 2 years: absence of impairment, defined as no disability or problems with behaviour and development. Economic: cost per 'quitter'. One thousand and fifty women enrolled (521 NRT, 529 placebo). There were 1010 live singleton births and 12 participants had live twins, while there were 14 fetal deaths and no birth data for 14

  13. Commencement of Geoparks, Geology day and International Earth Science Olympiad, IYPE in Japan

    NASA Astrophysics Data System (ADS)

    Tsukuda, Eikichi; Kodama, Kisaburo; Miyazaki, Teruki

    2010-05-01

    The GSJ is the main supporting organization of IYPE Japan, which is an implementation body of IYPE in Japan, serving as its secretariat. During the IYPE triennial activity, the GSJ has been supporting development of Geparks, establishment of "the Geology Day" and the Earth Science Olympiad activities with some academic societies, and has distributed geological maps with IYPE logo. The GSJ also established an outreach network "Geo-networks Tsukuba" as a local legacy of the IYPE, and has managed it with a local government, research organizations, nonprofit corporations and local media to increase geological and environmental literacy of public, especially among young people. The GSJ-AIST has also contributed internationally to IYPE by joining two international projects, OneGeology and the CCOP Book project. Geoparks in Japan are characterized by following features. The Japanese Islands and the surrounding seas are situated in the area of unique geologic features; the place where several tectonic plates meet and collide. This causes earthquakes and volcanic activities, and makes Japan one of most dynamic areas on the earth. The dynamics of the earth bring about not only geological hazards but also a lot of blessings. In August of 2009, three Geoparks, the Toya Caldera and Usu Volcano Geopark, the Itoigawa Geopark and the Unzen Volcanic Area Geopark, were accepted to join the Global Geopark Network from Japan for the first time. Since its launch in 2006, the GSJ has been playing a major role in promoting Geoparks in Japan together with Geological Society of Japan. The GSJ hosts the Japan Geopark Committee (JGC) for quality evaluation, serving as the information center of Geoparks in Japan. The Geology Day of Japan (10th of May) has been set up by the academic societies for geology in Japan and GSJ in 2007. The Geology Day is expected to provide the chances for the public to enjoy field trips and excursions and to understand the importance of geo-diversity. The Day

  14. Endocrinological Responses to the Administration of Nicotine: Interactions with Drug Initiation, Conditioned Effects, and Conditions of Stress

    DTIC Science & Technology

    1984-01-27

    j ec t i on in dogs and o ther species (Kiser , Booher & Wat ts , 1956; N a r i t a , Shiba ta , Waki , Egashira fi Suzuki , 1973) produce an...Narita, Shibata, Waki & Egashira, 1973), i t was found that intravenous nicot ine (0.1 mg/kg) produced an increase in the secretion of 17-OH 2 1 c o r

  15. Cross-Cultural Learning Approaches in Students from the USA, Japan and Taiwan

    ERIC Educational Resources Information Center

    Brown, Michael B.; Aoshima, Megumi; Bolen, Larry M.; Chia, Rosina; Kohyama, Takaya

    2007-01-01

    The purpose of this study is to examine the relationship between approaches to learning and locus of control of students from the USA, Japan, and Taiwan. The results show that students from the USA utilized more rote memory learning compared to students from Japan and Taiwan, while students from Japan were more likely to be "Achieving"…

  16. [The National Vaccine Injury Compensation Program in Japan].

    PubMed

    Ihara, Toshiaki

    2011-09-01

    Two vaccination systems have been employed in Japan, the routine vaccination and the voluntary vaccination. The National Vaccine Injury Compensation Program in Japan is no-fault system. Claims after the routine vaccination are demanded to the Ministry of Health, Labour and Welfare through local governments, and compensation is more expenses. Meanwhile, claims after the voluntary vaccination are demanded to the Pharmaceuticals and Medical Device Agency directly, and compensation is less compared with the routine vaccination.

  17. The Independent Living Movement in Asia: Solidarity from Japan

    ERIC Educational Resources Information Center

    Hayashi, Reiko; Okuhira, Masako

    2008-01-01

    Independent living movements of disabled people are emerging in Asian countries, supported by independent living centres (ILCs) in Japan. A study was conducted in Japan to explore the impact of the training program offered by Japanese ILCs to disabled people from other Asian countries. A sample of 35 people was selected by a snowballing method.…

  18. Legalized abortion in Japan.

    PubMed

    Hart, T M

    1967-10-01

    The enactment of the Eugenic Protection Act in Japan was followed by many changes. The population explosion was stemmed, the birth rate was halved, and while the marriage rate remained steady the divorce rate declined. The annual total of abortions increased until 1955 and then slowly declined. The highest incidence of abortions in families is in the 30 to 34 age group when there are four children in the family. As elsewhere abortion in advanced stages of pregnancy is associated with high morbidity and mortality. There is little consensus as to the number of criminal abortions. Reasons for criminal abortions can be found in the legal restrictions concerning abortion: Licensing of the abortionist, certification of hospitals, taxation of operations and the requirement that abortion be reported. Other factors are price competition and the patient's desire for secrecy. Contraception is relatively ineffective as a birth control method in Japan. Oral contraceptives are not yet government approved. In 1958 alone 1.1 per cent of married women were sterilized and the incidence of sterilization was increasing.

  19. The imminent healthcare and emergency care crisis in Japan.

    PubMed

    Suzuki, Tetsuji; Nishida, Masamichi; Suzuki, Yuriko; Kobayashi, Kunio

    2008-05-01

    Japan has a universal healthcare system, and this paper describes the reality of the healthcare services provided, as well as current issues with the system. Academic, government, and press reports on Japanese healthcare systems and healthcare guidelines were reviewed. The universal healthcare system of Japan is considered internationally to be both low-cost and effective because the Japanese population enjoys good health status with a long life expectancy, while healthcare spending in Japan is below the average given by the Organization for Economic Corporation and Development (OECD). However, in many regions of Japan the existing healthcare resources are seriously inadequate, especially with regard to the number of physicians and other health professionals. Because healthcare is traditionally viewed as "sacred" work in Japan, healthcare professionals are expected to make large personal sacrifices. Also, public attitudes toward medical malpractice have changed in recent decades, and medical professionals are facing legal issues without experienced support of the government or legal professionals. Administrative response to the lack of resources and collaboration among communities are beginning, and more efficient control and management of the healthcare system is under consideration. The Japanese healthcare system needs to adopt an efficient medical control organization to ease the strain on existing healthcare professionals and to increase the number of physicians and other healthcare resources. Rather than continuing to depend on healthcare professionals being able and willing to make personal sacrifices, the government, the public and medical societies must cooperate and support changes in the healthcare system.

  20. The origins of scientific psychology in Japan.

    PubMed

    Takasuna, Miki

    2006-01-01

    The origins of scientific psychology in Japan arrived primarily through six routes. First, psychology was imported through translations by Amane Nishi, which resulted in the coining of words such as "psychology," "subject," and "object." Second, psychology arrived in the form of education that was directed by American Christian missionaries. The third route brought psychology through lectures presented at universities (e.g., Masakazu Toyama began lecturing at the University of Tokyo in 1877). The fourth route relates to teacher education: Shuji Izawa and Hideo Takamine introduced psychology as part of the first curriculum at Tokyo Higher Normal School in 1879. The fifth route was created by Japanese philosophers who studied abroad, such as Tetsujiro Inouye. Finally, the sixth and most important avenue involved the introduction of experimental psychology, as well as a formal educational curriculum for psychologists (e.g., Yujiro Motora was the first Japanese to introduce experimental psychology to Japan, where he trained many students). Consequently, the establishment of scientific psychology in Japan was primarily owed to the Japanese scholars who studied abroad in the U.S. and Germany.

  1. [Neurology in Japan before World War II].

    PubMed

    Takahashi, Akira

    2013-01-01

    Modern Western medicine was introduced into Japan by a Dutch doctor Pompe van Meerdervoort in 1855. A German physician EOE von Balz devoted himself to educating medicine at Tokyo Medical School, the predecessor of the present University of Tokyo for 25 years. Hiroshi Kawahara and Kinnosuke Miura, pioneers of Japan Neurology, received their education by him. Kawahara first described X-linked bulvo-spinal muscular atrophy, and published the first Japanese textbook of clinical neurology in 1897. In 1902, Miura and others founded the Japanese Society of Neuro-Psychiatry, the forerunner of the present " Japanese Society of Neurology ". Both Seizo Katsunuma, Professor of Nagoya University, and Junnjiro Kato, Professor of Tohoku University, succeeded Miura's neurology. Miura investigated into the cause of beriberi, but ended in failure. Hasegawa's proposal at the Diet in 1894 that the Japan Government should found an independent department of neurology in the University of Tokyo was unfortunately rejected. There was no foundation of independent institute, department and clinic of neurology before World War II. Consequently Japanese neurology was on the ebb at that time.

  2. Citrus breeding, genetics and genomics in Japan

    PubMed Central

    Omura, Mitsuo; Shimada, Takehiko

    2016-01-01

    Citrus is one of the most cultivated fruits in the world, and satsuma mandarin (Citrus unshiu Marc.) is a major cultivated citrus in Japan. Many excellent cultivars derived from satsuma mandarin have been released through the improvement of mandarins using a conventional breeding method. The citrus breeding program is a lengthy process owing to the long juvenility, and it is predicted that marker-assisted selection (MAS) will overcome the obstacle and improve the efficiency of conventional breeding methods. To promote citrus molecular breeding in Japan, a genetic mapping was initiated in 1987, and the experimental tools and resources necessary for citrus functional genomics have been developed in relation to the physiological analysis of satsuma mandarin. In this paper, we review the progress of citrus breeding and genome researches in Japan and report the studies on genetic mapping, expression sequence tag cataloguing, and molecular characterization of breeding characteristics, mainly in terms of the metabolism of bio-functional substances as well as factors relating to, for example, fruit quality, disease resistance, polyembryony, and flowering. PMID:27069387

  3. Practical aspects of designing and conducting pharmacoeconomic studies in Japan.

    PubMed

    Doherty, Jim; Sato, Keiko

    2003-01-01

    The advent of simultaneous global clinical trials and drug registration strategies has increased the demand for global pharmacoeconomic strategies. Outcomes researchers in pharmaceutical companies are faced with the challenge of assessing at a strategic level what pharmacoeconomic data are most useful in Japan and when, and then deciding at a tactical level what type of study designs are feasible. This paper is written mainly for the benefit of researchers working outside of Japan in the pharmaceutical/medical device industry or academia who are interested in conducting research in Japan. We reviewed the existing pharmacoeconomic literature in Japan, and found that the number of studies per year has been steadily increasing. The majority of studies have been cost-effectiveness and cost-consequence analyses. Typical data sources available in Japan are somewhat limited compared with other Western countries. However, charge data can be easily accessed through the national uniform reimbursement fee system and these data are particularly relevant for pharmaceutical pricing negotiations with the Ministry of Health, Labor and Welfare (MHLW). The present use of pharmacoeconomic data by pharmaceutical companies is mainly for pricing negotiations but recent reforms make certain types of data useful for marketing strategies too. The demand for pharmacoeconomic data may increase because of upcoming MHLW pharmaceutical pricing and/or recent health insurance system reforms. Economic evaluation of medical technologies in Japan, though lagging behind North America, Australia and Europe, has the potential to rapidly gather momentum as increasing cost-escalation worries contribute to a growing interest in pharmacoeconomic data.

  4. History of Japan-U.S./High Pressure Mineral Physics Seminars: 1976 to 2012

    NASA Astrophysics Data System (ADS)

    Liebermann, Robert Cooper

    2014-03-01

    Under the auspices of the U.S.-Japan Cooperative Science Program between the U.S. National Science Foundation and the Japan Society for the Promotion of Science, the first U.S.-Japan joint seminar on High Pressure Research Applications in Geophysics was held in Honolulu, Hawaii, 5-8 July 1976 and was attended by 47 scientists. Originated as bilateral U.S.-Japan seminars on high-pressure research applications in geophysics by Murli Manghnani and Syun-iti Akimoto, this series continued at 5-year intervals under those auspices from 1976 to 1996 [1981 in Hakone, Japan 1986 in Turtle Bay, Hawaii, 1991 in Ise, Japan, and 1996 in Maui, Hawaii], with venues alternating between Hawaii and Japan. In the 21st century, as a result of growing international interest in high-pressure mineral physics, the seminar series was re-envisioned with a broader focus “more international” focus than the original U.S.-Japan bilateral series. The first of the new meetings entitled “High Pressure Mineral Physics Seminars” [HPMP-6] took place in Verbania, Italy on August 26-31, 2002. More than 84 scientists from Asia, Australia, the Americas and Europe attended. HPMPS-7 took place in Matsushima, Japan on May 8-12, 2007 and was attended by 134 scientists from throughout the world. In this paper, we review this history culminating with the HPMPS-8 at Lake Tahoe, California in July 2012, which was held jointly with the Annual Meeting of COMPRES: Consortium for Materials Properties Research in Earth Sciences.

  5. Great East Japan Earthquake Tsunami

    NASA Astrophysics Data System (ADS)

    Iijima, Y.; Minoura, K.; Hirano, S.; Yamada, T.

    2011-12-01

    The 11 March 2011, Mw 9.0 Great East Japan Earthquake, already among the most destructive earthquakes in modern history, emanated from a fault rupture that extended an estimated 500 km along the Pacific coast of Honshu. This earthquake is the fourth among five of the strongest temblors since AD 1900 and the largest in Japan since modern instrumental recordings began 130 years ago. The earthquake triggered a huge tsunami, which invaded the seaside areas of the Pacific coast of East Japan, causing devastating damages on the coast. Artificial structures were destroyed and planted forests were thoroughly eroded. Inrush of turbulent flows washed backshore areas and dunes. Coastal materials including beach sand were transported onto inland areas by going-up currents. Just after the occurrence of the tsunami, we started field investigation of measuring thickness and distribution of sediment layers by the tsunami and the inundation depth of water in Sendai plain. Ripple marks showing direction of sediment transport were the important object of observation. We used a soil auger for collecting sediments in the field, and sediment samples were submitted for analyzing grain size and interstitial water chemistry. Satellite images and aerial photographs are very useful for estimating the hydrogeological effects of tsunami inundation. We checked the correspondence of micro-topography, vegetation and sediment covering between before and after the tsunami. The most conspicuous phenomenon is the damage of pine forests planted in the purpose of preventing sand shifting. About ninety-five percent of vegetation coverage was lost during the period of rapid currents changed from first wave. The landward slopes of seawalls were mostly damaged and destroyed. Some aerial photographs leave detailed records of wave destruction just behind seawalls, which shows the occurrence of supercritical flows. The large-scale erosion of backshore behind seawalls is interpreted to have been caused by

  6. Nicotine, Carcinogen, and Toxin Exposure in Long-Term E-Cigarette and Nicotine Replacement Therapy Users: A Cross-sectional Study.

    PubMed

    Shahab, Lion; Goniewicz, Maciej L; Blount, Benjamin C; Brown, Jamie; McNeill, Ann; Alwis, K Udeni; Feng, June; Wang, Lanqing; West, Robert

    2017-03-21

    Given the rapid increase in the popularity of e-cigarettes and the paucity of associated longitudinal health-related data, the need to assess the potential risks of long-term use is essential. To compare exposure to nicotine, tobacco-related carcinogens, and toxins among smokers of combustible cigarettes only, former smokers with long-term e-cigarette use only, former smokers with long-term nicotine replacement therapy (NRT) use only, long-term dual users of both combustible cigarettes and e-cigarettes, and long-term users of both combustible cigarettes and NRT. Cross-sectional study. United Kingdom. The following 5 groups were purposively recruited: combustible cigarette-only users, former smokers with long-term (≥6 months) e-cigarette-only or NRT-only use, and long-term dual combustible cigarette-e-cigarette or combustible cigarette-NRT users (n = 36 to 37 per group; total n = 181). Sociodemographic and smoking characteristics were assessed. Participants provided urine and saliva samples and were analyzed for biomarkers of nicotine, tobacco-specific N-nitrosamines (TSNAs), and volatile organic compounds (VOCs). After confounders were controlled for, no clear between-group differences in salivary or urinary biomarkers of nicotine intake were found. The e-cigarette-only and NRT-only users had significantly lower metabolite levels for TSNAs (including the carcinogenic metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol [NNAL]) and VOCs (including metabolites of the toxins acrolein; acrylamide; acrylonitrile; 1,3-butadiene; and ethylene oxide) than combustible cigarette-only, dual combustible cigarette-e-cigarette, or dual combustible cigarette-NRT users. The e-cigarette-only users had significantly lower NNAL levels than all other groups. Combustible cigarette-only, dual combustible cigarette-NRT, and dual combustible cigarette-e-cigarette users had largely similar levels of TSNA and VOC metabolites. Cross-sectional design with self-selected sample. Former

  7. Impact of neonatal resuscitation trainings on neonatal and perinatal mortality: a systematic review and meta-analysis

    PubMed Central

    Patel, Archana; Kurhe, Kunal; Bhargava, Savita; Bang, Akash

    2017-01-01

    Background Training of birth attendants in neonatal resuscitation is likely to reduce birth asphyxia and neonatal mortality. We performed a systematic review and meta-analysis to assess the impact of neonatal resuscitation training (NRT) programme in reducing stillbirths, neonatal mortality, and perinatal mortality Methods We considered studies where any NRT was provided to healthcare personnel involved in delivery process and handling of newborns. We searched MEDLINE, CENTRAL, ERIC and other electronic databases. We also searched ongoing trials and bibliographies of the retrieved articles, and contacted experts for unpublished work. We undertook screening of studies and assessment of risk of bias in duplicates. We performed review according to Cochrane Handbook. We assessed the quality of evidence using the GRADE approach. Results We included 20 trials with 1 653 805 births in this meta-analysis. The meta-analysis of NRT versus control shows that NRT decreases the risk of all stillbirths by 21% (RR 0.79, 95% CI 0.44 to 1.41), 7-day neonatal mortality by 47% (RR 0.53, 95% CI 0.38 to 0.73), 28-day neonatal mortality by 50% (RR 0.50, 95% CI 0.37 to 0.68) and perinatal mortality by 37% (RR 0.63, 95% CI 0.42 to 0.94). The meta-analysis of pre-NRT versus post-NRT showed that post-NRT decreased the risk of all stillbirths by 12% (RR 0.88, 95% CI 0.83 to 0.94), fresh stillbirths by 26% (RR 0.74, 95% CI 0.61 to 0.90), 1-day neonatal mortality by 42% (RR 0.58, 95% CI 0.42 to 0.82), 7-day neonatal mortality by 18% (RR 0.82, 95% CI 0.73 to 0.93), 28-day neonatal mortality by 14% (RR 0.86, 95% CI 0.65 to 1.13) and perinatal mortality by 18% (RR 0.82, 95% CI 0.74 to 0.91). Conclusions Findings of this review show that implementation of NRT improves neonatal and perinatal mortality. Further good quality randomised controlled trials addressing the role of NRT for improving neonatal and perinatal outcomes may be warranted. Trial registration number PROSPERO

  8. Influence of nutrient signals and carbon allocation on the expression of phosphate and nitrogen transporter genes in winter wheat (Triticum aestivum L.) roots colonized by arbuscular mycorrhizal fungi

    PubMed Central

    Tian, Hui; Yuan, Xiaolei; Duan, Jianfeng; Li, Wenhu; Zhai, Bingnian; Gao, Yajun

    2017-01-01

    Arbuscular mycorrhizal (AM) colonization of plant roots causes the down-regulation of expression of phosphate (Pi) or nitrogen (N) transporter genes involved in direct nutrient uptake pathways. The mechanism of this effect remains unknown. In the present study, we sought to determine whether the expression of Pi or N transporter genes in roots of winter wheat colonized by AM fungus responded to (1) Pi or N nutrient signals transferred from the AM extra-radical hyphae, or (2) carbon allocation changes in the AM association. A three-compartment culture system, comprising a root compartment (RC), a root and AM hyphae compartment (RHC), and an AM hyphae compartment (HC), was used to test whether the expression of Pi or N transporter genes responded to nutrients (Pi, NH4+ and NO3-) added only to the HC. Different AM inoculation density treatments (roots were inoculated with 0, 20, 50 and 200 g AM inoculum) and light regime treatments (6 hours light and 18 hours light) were established to test the effects of carbon allocation on the expression of Pi or N transporter genes in wheat roots. The expression of two Pi transporter genes (TaPT4 and TaPHT1.2), five nitrate transporter genes (TaNRT1.1, TaNRT1.2, TaNRT2.1, TaNRT2.2, and TaNRT2.3), and an ammonium transporter gene (TaAMT1.2) was quantified using real-time polymerase chain reaction. The expression of TaPT4, TaNRT2.2, and TaAMT1.2 was down-regulated by AM colonization only when roots of host plants received Pi or N nutrient signals. However, the expression of TaPHT1.2, TaNRT2.1, and TaNRT2.3 was down-regulated by AM colonization, regardless of whether there was nutrient transfer from AM hyphae. The expression of TaNRT1.2 was also down-regulated by AM colonization even when there was no nutrient transfer from AM hyphae. The present study showed that an increase in carbon consumption by the AM fungi did not necessarily result in greater down-regulation of expression of Pi or N transporter genes. PMID:28207830

  9. Influence of nutrient signals and carbon allocation on the expression of phosphate and nitrogen transporter genes in winter wheat (Triticum aestivum L.) roots colonized by arbuscular mycorrhizal fungi.

    PubMed

    Tian, Hui; Yuan, Xiaolei; Duan, Jianfeng; Li, Wenhu; Zhai, Bingnian; Gao, Yajun

    2017-01-01

    Arbuscular mycorrhizal (AM) colonization of plant roots causes the down-regulation of expression of phosphate (Pi) or nitrogen (N) transporter genes involved in direct nutrient uptake pathways. The mechanism of this effect remains unknown. In the present study, we sought to determine whether the expression of Pi or N transporter genes in roots of winter wheat colonized by AM fungus responded to (1) Pi or N nutrient signals transferred from the AM extra-radical hyphae, or (2) carbon allocation changes in the AM association. A three-compartment culture system, comprising a root compartment (RC), a root and AM hyphae compartment (RHC), and an AM hyphae compartment (HC), was used to test whether the expression of Pi or N transporter genes responded to nutrients (Pi, NH4+ and NO3-) added only to the HC. Different AM inoculation density treatments (roots were inoculated with 0, 20, 50 and 200 g AM inoculum) and light regime treatments (6 hours light and 18 hours light) were established to test the effects of carbon allocation on the expression of Pi or N transporter genes in wheat roots. The expression of two Pi transporter genes (TaPT4 and TaPHT1.2), five nitrate transporter genes (TaNRT1.1, TaNRT1.2, TaNRT2.1, TaNRT2.2, and TaNRT2.3), and an ammonium transporter gene (TaAMT1.2) was quantified using real-time polymerase chain reaction. The expression of TaPT4, TaNRT2.2, and TaAMT1.2 was down-regulated by AM colonization only when roots of host plants received Pi or N nutrient signals. However, the expression of TaPHT1.2, TaNRT2.1, and TaNRT2.3 was down-regulated by AM colonization, regardless of whether there was nutrient transfer from AM hyphae. The expression of TaNRT1.2 was also down-regulated by AM colonization even when there was no nutrient transfer from AM hyphae. The present study showed that an increase in carbon consumption by the AM fungi did not necessarily result in greater down-regulation of expression of Pi or N transporter genes.

  10. Use of nicotine replacement therapy and stop-smoking medicines in a national sample of Aboriginal and Torres Strait Islander smokers and ex-smokers.

    PubMed

    Thomas, David P; Briggs, Viki L; Couzos, Sophia; Panaretto, Kathryn S; van der Sterren, Anke E; Stevens, Matthew; Borland, Ron

    2015-06-01

    To examine the use of nicotine replacement therapy (NRT) and the stop-smoking medicines (SSMs) varenicline and bupropion in a national sample of Aboriginal and Torres Strait Islander smokers and recent ex-smokers. The Talking About The Smokes (TATS) project used a quota sampling design to recruit a nationally representative sample of 1721 smokers and ex-smokers who had quit ≤ 12 months before from communities served by 34 Aboriginal community-controlled health services and one community in the Torres Strait. Baseline surveys were conducted from April 2012 to October 2013. These were compared with 1017 daily smokers from the general Australian population surveyed by the International Tobacco Control Policy Evaluation Project (ITC Project) from July 2010 to May 2011. Past and intended use of NRT and SSMs, duration of use, and whether participants thought NRT and SSMs help smokers to quit. Compared with other daily Australian smokers, lower proportions of Aboriginal and Torres Strait Islander daily smokers had ever used any NRT or SSMs (TATS, 37% v ITC, 58.5%) or used them in the past year (TATS, 23% v ITC, 42.1%). Nicotine patches were most commonly used by Aboriginal and Torres Strait Islander smokers and recent ex-smokers (24%), followed by varenicline (11%) and nicotine gum (10%); most (74%) had got their last NRT at no cost. Among dependent Aboriginal and Torres Strait Islander daily smokers, those who were more socioeconomically advantaged were more likely than the disadvantaged to have used NRT or SSMs. Similar proportions of Aboriginal and Torres Strait Islander daily smokers and other Australian daily smokers said that NRT or SSMs help smokers to quit (TATS, 70% v ITC, 74.2%). Dependent Aboriginal and Torres Strait Islander smokers who had previously used NRT or SSMs were more likely to believe they help in quitting and to intend to use them in the future. Aboriginal and Torres Strait Islander daily smokers, particularly those who are most disadvantaged

  11. 78 FR 31577 - Diffusion-Annealed, Nickel-Plated Flat-Rolled Steel Products From Japan

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-24

    ..., Nickel-Plated Flat-Rolled Steel Products From Japan Determination On the basis of the record \\1... imports from Japan of diffusion-annealed, nickel-plated flat-rolled steel products, provided for primarily... flat-rolled steel products from Japan. Accordingly, effective March 27, 2013, the Commission instituted...

  12. Current status and perspectives of cysticercosis and taeniasis in Japan.

    PubMed

    Yamasaki, Hiroshi

    2013-02-01

    This mini-review describes recent epidemiological trends in cysticercosis and taeniasis in Japan. Some of the topics discussed herein were presented at the first symposium on "Current perspectives of Taenia asiatica researches", that was held in Osong in Chungbuk Province, South Korea, in October 2011 and organized by Prof. K. S. Eom, Chungbuk National University School of Medicine. To better understand the trends in the occurrence of cysticercosis and taeniasis in Japan, clinical cases reported in 2005 have been updated. In addition, the current status of Taenia asiatica infections successively occurring in Japan since 2010 is also discussed.

  13. Current Status and Perspectives of Cysticercosis and Taeniasis in Japan

    PubMed Central

    2013-01-01

    This mini-review describes recent epidemiological trends in cysticercosis and taeniasis in Japan. Some of the topics discussed herein were presented at the first symposium on "Current perspectives of Taenia asiatica researches", that was held in Osong in Chungbuk Province, South Korea, in October 2011 and organized by Prof. K. S. Eom, Chungbuk National University School of Medicine. To better understand the trends in the occurrence of cysticercosis and taeniasis in Japan, clinical cases reported in 2005 have been updated. In addition, the current status of Taenia asiatica infections successively occurring in Japan since 2010 is also discussed. PMID:23467264

  14. [Films: China and Japan].

    ERIC Educational Resources Information Center

    Gumport, Roberta H.

    The history of filmmaking in China and Japan and film usage in teaching are considered in this document. Pointing out how films describe historical context and culture, the document also describes various techniques of film making. Films in China were heavily influenced by western models and have tended to be tools of the power structure, as…

  15. Precursory Slope Deformation around Landslide Area Detected by Insar Throughout Japan

    NASA Astrophysics Data System (ADS)

    Nakano, T.; Wada, K.; Yamanaka, M.; Kamiya, I.; Nakajima, H.

    2016-06-01

    Interferometric Synthetic Aperture Radar (InSAR) technique is able to detect a slope deformation around landslide (e.g., Singhroy et al., 2004; Une et al., 2008; Riedel and Walther, 2008; Sato et al., 2014). Geospatial Information Authority (GSI) of Japan has been performing the InSAR analysis regularly by using ALOS/PALSAR data and ALOS-2/PALSAR-2 data throughout Japan. There are a lot of small phase change sites except for crustal deformation with earthquake or volcano activity in the InSAR imagery. Most of the phase change sites are located in landslide area. We conducted field survey at the 10 sites of those phase change sites. As a result, we identified deformation of artificial structures or linear depressions caused by mass movement at the 9 sites. This result indicates that InSAR technique can detect on the continual deformation of landslide block for several years. GSI of Japan will continue to perform the InSAR analysis throughout Japan. Therefore, we will be able to observe and monitor precursory slope deformation around landslide areas throughout Japan.

  16. Occurrence of human respiratory syncytial virus in summer in Japan.

    PubMed

    Shobugawa, Y; Takeuchi, T; Hibino, A; Hassan, M R; Yagami, R; Kondo, H; Odagiri, T; Saito, R

    2017-01-01

    In temperate zones, human respiratory syncytial virus (HRSV) outbreaks typically occur in cold weather, i.e. in late autumn and winter. However, recent outbreaks in Japan have tended to start during summer and autumn. This study examined associations of meteorological conditions with the numbers of HRSV cases reported in summer in Japan. Using data from the HRSV national surveillance system and national meteorological data for summer during the period 2007-2014, we utilized negative binomial logistic regression analysis to identify associations between meteorological conditions and reported cases of HRSV. HRSV cases increased when summer temperatures rose and when relative humidity increased. Consideration of the interaction term temperature × relative humidity enabled us to show synergistic effects of high temperature with HRSV occurrence. In particular, HRSV cases synergistically increased when relative humidity increased while the temperature was ⩾28·2 °C. Seasonal-trend decomposition analysis using the HRSV national surveillance data divided by 11 climate divisions showed that summer HRSV cases occurred in South Japan (Okinawa Island), Kyushu, and Nankai climate divisions, which are located in southwest Japan. Higher temperature and higher relative humidity were necessary conditions for HRSV occurrence in summer in Japan. Paediatricians in temperate zones should be mindful of possible HRSV cases in summer, when suitable conditions are present.

  17. A review of liquid rocket propulsion programs in Japan

    NASA Technical Reports Server (NTRS)

    Merkle, Charles L.

    1991-01-01

    An assessment of Japan's current capabilities in the areas of space and transatmospheric propulsion is presented. The primary focus is upon Japan's programs in liquid rocket propulsion and in space plane and related transatmospheric areas. Brief reference is also made to their solid rocket programs, as well as to their supersonic air breathing propulsion efforts that are just getting underway.

  18. Recent Progress of Seismic Observation Networks in Japan

    NASA Astrophysics Data System (ADS)

    Okada, Y.

    2013-04-01

    Before the occurrence of disastrous Kobe earthquake in 1995, the number of high sensitivity seismograph stations operated in Japan was nearly 550 and was concentrated in the Kanto and Tokai districts, central Japan. In the wake of the Kobe earthquake, Japanese government has newly established the Headquarters for Earthquake Research Promotion and started the reconstruction of seismic networks to evenly cover the whole Japan. The basic network is composed of three seismographs, i.e. high sensitivity seismograph (Hi-net), broadband seismograph (F-net), and strong motion seismograph (K-NET). A large majority of Hi-net stations are also equipped with a pair of strong motion sensors at the bottom of borehole and the ground surface (KiK-net). A plenty of high quality data obtained from these networks are circulated at once and is producing several new seismological findings as well as providing the basis for the Earthquake Early Warning system. In March 11, 2011, "Off the Pacific coast of Tohoku Earthquake" was generated with magnitude 9.0, which records the largest in the history of seismic observation in Japan. The greatest disaster on record was brought by huge tsunami with nearly 20 thousand killed or missing people. We are again noticed that seismic observation system is quite poor in the oceanic region compared to the richness of it in the inland region. In 2012, NIED has started the construction of ocean bottom seismic and tsunami observation network along the Japan Trench. It is planned to layout 154 stations with an average spacing of 30km, each of which is equipped with an accelerometer for seismic observation and a water pressure gauge for tsunami observation. We are expecting that more rapid and accurate warning of earthquake and tsunami becomes possible by this observing network.

  19. Okinawa: an exception to the social gradient of life expectancy in Japan.

    PubMed

    Cockerham, W C; Yamori, Y

    2001-01-01

    This paper examines why the social gradient of life expectancy does not apply in Japan when Okinawa is considered. The social gradient thesis links differences in longevity to social rank, with people and populations in higher status hierarchical positions having lower mortality and longer life expectancies than those beneath them in the social scale. Japan has been cited as a major example of this thesis in that Japanese life expectancy improved dramatically as Japan rose to the top echelon of nations in economic rank in the late 20th century. Thus it follows that Japan's most affluent and leading prefectures should be the major catalysts behind the nation's rise in life expectancy as well to the number one position in the world. However, this is not the case as life expectancy in Okinawa, Japan's poorest prefecture, exceeds that of Japan as a whole. We find that the social gradient of life expectancy does not apply at the prefectural level and question its validity for geographical areas. We suggest that healthy lifestyles, especially diet and the social support of family and friends, are more important than sense of hierarchy for longevity in Okinawa.

  20. Sapporo, Hokkaido, Japan

    NASA Image and Video Library

    1992-09-20

    The city of Sapporo on the northernmost of the Japanese Home Island of Hokkaido (43.5N, 141.5E), host to the 1986 Winter Olympic Games is situated along the margin of a large valley which extends across the island from the Sea of Japan to the Pacific Ocean. The Valley is largely cultivated (the lighter green of the cultivated land distinguishes it from the gray urban development of Sapporo), but much of the island remains heavily forested.

  1. Letter: Imported paracoccidioidomycosis in Japan.

    PubMed

    Onda, Hiroshi; Komine, Mayumi; Murata, Satoru; Ohtsuki, Mamitaro

    2011-12-15

    A 39-year-old man from Argentina, who had come to Japan 13 years previously, had been suffering from oral pain for several months. He was biopsied twice and treated with oral predonisolone without improvement. A number of white granular lesions with erosions were observed on the hard palate and buccal mucosa. Histopathological examination revealed a well-demarcated abscess with an accumulation of neutrophils, surrounded by epithelioid cell granulomas. Round eosinophilic bodies, considered to be fungal elements, positive for PAS and Grocott staining, were observed. Chest CT revealed cavities in the lung. A white yeast-like colony was cultured from bronchial lavage fluid and Paracoccidioides brasiliensis was identified. The patient was treated with liposomal amphotericin B followed by oral itraconazole 400 mg/day, with a favorable clinical course. Paracoccidioidomycosis, an imported mycosis, is rare in Japan and sometimes causes difficulty in diagnosis, resulting in inappropriate treatment.

  2. Child abuse and neglect in Japan: coin-operated-locker babies.

    PubMed

    Kouno, A; Johnson, C F

    1995-01-01

    The coin-operated-locker baby is a type of child abuse that may be unique to Japan. The term refers to newborns who are placed, while alive or dead, in coin-operated lockers. This practice has been decreased by specific measures. It is likely that social and economic variables in Japan account for differences in the frequency and types of child abuse cases when compared to American or European societies as social conditions in Japan change the reported incidence of child abuse may increase in the future. Recently, the government of Osaka organized a group specifically designed to deal with the detection and protection of abused and neglected children. In 1993, they published a manual on how to deal with child abuse, but the Japanese judicial administration still uses old laws for abuse cases. The development of new laws is occurring in parts of the country now. This paper introduces the present status of coping with child abuse and neglect in Japan.

  3. Arms production in Japan: The military applications of civilian technology

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Drifte, R.

    1986-01-01

    The author examines both the domestic and international environments encouraging Japan's leaders not only to strengthen the country's defense, but to do so more independently. Until recently, the arms industry has been nurtured by U.S. weapons technology, but growing dependence on electronics dramatically increases Japan's contribution to modern weapons systems. The electronics revolution is creating more and more dual-purpose products, undermining the Japanese cabinet policy of prohibiting arms export. The discovery of wider applications for Japanese manufacturers' most advanced civilian technology is a strong motivation for entering the arms arena. The book illustrates that Japan's entry into the field ismore » a dynamic example of the success of Japanese industry as it enters new technological areas. The author discusses: Development and the Present Situation of Japan's Arms Production Capability; Research and Development; The Shipbuilding Industry; The Aircraft Industry; The Space and Missile Industry; and Arms Exports with conclusions.« less

  4. The Development of Astronomy and Emergence of Astrophysics in Japan

    NASA Astrophysics Data System (ADS)

    Nakamura, Tsuko

    This chapter overviews the emergence and development phases of modern astronomy and astrophysics in Japan, mainly before WWII. In the beginning of the nineteenth century under the samurai regime of the Tokugawa Shogunate, shogunal astronomers started to learn Western astronomy through a Dutch translation of the book Astronomie by J.J. Lalande. After the Meiji Restoration (1868) the new government founded the University of Tokyo (1877), the first modern university in Japan, in which Tokyo Astronomical Observatory (TAO) also started in 1888. Terao Hisashi, who had gone to Paris to study the modern astronomy, became the first Director of TAO in 1888. The astronomy introduced by Terao into Japan was so-called classical astronomy. Two of Terao's early students made Japan's first internationally recognized achievements in astronomy, the discovery of the Z-term in the polar motion of the Earth by Kimura (Astronomische Nachrichten, 158, 234-240, 1902) and the discovery of asteroid families by Hirayama (Astronomical Journal, 31, 185-188, 1918).

  5. Distinct Thalamic Reticular Cell Types Differentially Modulate Normal and Pathological Cortical Rhythms.

    PubMed

    Clemente-Perez, Alexandra; Makinson, Stefanie Ritter; Higashikubo, Bryan; Brovarney, Scott; Cho, Frances S; Urry, Alexander; Holden, Stephanie S; Wimer, Matthew; Dávid, Csaba; Fenno, Lief E; Acsády, László; Deisseroth, Karl; Paz, Jeanne T

    2017-06-06

    Integrative brain functions depend on widely distributed, rhythmically coordinated computations. Through its long-ranging connections with cortex and most senses, the thalamus orchestrates the flow of cognitive and sensory information. Essential in this process, the nucleus reticularis thalami (nRT) gates different information streams through its extensive inhibition onto other thalamic nuclei, however, we lack an understanding of how different inhibitory neuron subpopulations in nRT function as gatekeepers. We dissociated the connectivity, physiology, and circuit functions of neurons within rodent nRT, based on parvalbumin (PV) and somatostatin (SOM) expression, and validated the existence of such populations in human nRT. We found that PV, but not SOM, cells are rhythmogenic, and that PV and SOM neurons are connected to and modulate distinct thalamocortical circuits. Notably, PV, but not SOM, neurons modulate somatosensory behavior and disrupt seizures. These results provide a conceptual framework for how nRT may gate incoming information to modulate brain-wide rhythms. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  6. Current status of cardiovascular surgery in Japan, 2013 and 2014: A report based on the Japan Cardiovascular Surgery Database (JCVSD). 1: Mission and history of JCVSD.

    PubMed

    Takamoto, Shinichi; Motomura, Noboru; Miyata, Hiroaki; Tsukihara, Hiroyuki

    2018-01-01

    The Japan Cardiovascular Surgery Database (JCVSD) was created in 2000 with the support of the Society of Thoracic Surgeons (STS). The STS database content was translated to Japanese using the same disease criteria and in 2001, data entry for adult cardiac surgeries was initiated online using the University Hospital Medical Information Network (UMIN). In 2008, data entry for congenital heart surgeries was initiated in the congenital section of JCVSD and preoperative expected mortality (JapanSCORE) in adult cardiovascular surgeries was first calculated using the risk model of JCVSD. The Japan Surgical Board system merged with JCVSD in 2011, and all cardiovascular surgical data were registered in the JCVSD from 2012 onward. The reports resulting from the data analyses of the JCVSD will encourage further improvements in the quality of cardiovascular surgeries, patient safety, and medical care in Japan.

  7. Current husbandry situation of red pandas in Japan.

    PubMed

    Tanaka, Ai; Ogura, Tadatoshi

    2018-03-01

    The red panda (Ailurus fulgens) is an endangered semi-arboreal folivore with a specialized diet of bamboo leaves. Zoos worldwide maintain red pandas under a variety of housing environments and husbandry procedures that may affect the reproductive success and longevity of captive red pandas. The aims of the present study were to investigate how red pandas are kept in Japan and to obtain useful insights to increase their longevity by comparing the results from a questionnaire sent to Japanese zoos and those from a previous survey conducted in other countries. We received responses from 42 out of 52 zoos, holding a total of 219 individual red pandas, in Japan. The age-sex distribution indicated that red panda populations in Japan need close attention to be maintained sustainably. Of the husbandry aspects surveyed, the number of individuals in the same zoo, enclosure size, and the frequency of bamboo feeding factors indicated to affect reproductive success. Frequent monitoring of body weight, implementation of husbandry training, and bamboo feeding were also suggested as the reasons for the longevity of red pandas in Japan. Zoos were provided with sufficient physical features in on-exhibit enclosures, close monitoring for health status, and proper feeding, but other aspects of husbandry such as enclosure size and structures in off-exhibit spaces were insufficient and might compromise animal welfare. © 2018 Wiley Periodicals, Inc.

  8. [Acute infectious diseases in occupied Japan].

    PubMed

    Tanaka, Seiji; Sugita, Satoru; Moriyama, Takako; Marui, Eiji

    2007-06-01

    Japan's health statistics system, considered among the best in the world today, continually complies and organizes information about various infectious diseases. However, systematic surveillance was not conducted by the Ministry of Health and Welfare between World War II and the postwar period, creating a gap in health data. In contrast, the GHQ/SCAP/PHW. which was closely involved in health and medical reform during the Occupation, thoroughly investigated the health conditions of the Japanese people during this period. This article describes the trends in acute infectious diseases in Occupied Japan by using statistical records listed in the appendices of the "Weekly Bulletin", an official document of the GHQ/SCAP that is currently kept in the National Diet Library Modern Japanese Political History Materials Room.

  9. Performance of near real-time Global Satellite Mapping of Precipitation estimates during heavy precipitation events over northern China

    NASA Astrophysics Data System (ADS)

    Chen, Sheng; Hu, Junjun; Zhang, Asi; Min, Chao; Huang, Chaoying; Liang, Zhenqing

    2018-02-01

    This study assesses the performance of near real-time Global Satellite Mapping of Precipitation (GSMaP_NRT) estimates over northern China, including Beijing and its adjacent regions, during three heavy precipitation events from 21 July 2012 to 2 August 2012. Two additional near real-time satellite-based products, the Climate Prediction Center morphing method (CMORPH) and Precipitation Estimation from Remotely Sensed Information using Artificial Neural Networks-Cloud Classification System (PERSIANN-CCS), were used for parallel comparison with GSMaP_NRT. Gridded gauge observations were used as reference for a performance evaluation with respect to spatiotemporal variability, probability distribution of precipitation rate and volume, and contingency scores. Overall, GSMaP_NRT generally captures the spatiotemporal variability of precipitation and shows promising potential in near real-time mapping applications. GSMaP_NRT misplaced storm centers in all three storms. GSMaP_NRT demonstrated higher skill scores in the first high-impact storm event on 21 July 2015. GSMaP_NRT passive microwave only precipitation can generally capture the pattern of heavy precipitation distributions over flat areas but failed to capture the intensive rain belt over complicated mountainous terrain. The results of this study can be useful to both algorithm developers and the scientific end users, providing a better understanding of strengths and weaknesses to hydrologists using satellite precipitation products.

  10. Comparison of community reactions to traffic noise

    NASA Astrophysics Data System (ADS)

    Osada, Y.

    1991-12-01

    In 1989, the community reaction to aircraft noise was surveyed around the New Tokyo International Airport (Narita Airport) by means of an interview method. The questionnaire used in the survey was a modified version of a question sheet used in a study around Yokota Airbase in 1971. The results of these two surveys were compared. The response to questions on interference with conversation, talking on the telephone and listening to TV and radio was quite similar in the two studies. However, some differences were observed in the rates of interference with night sleep and reading and/or concentrating. This may be caused by differences between the two studies in aircraft flight patterns and occupations of the respondents. Such tendencies were also observed when the Narita survey was compared with other studies conducted around the airports of Yokota, Haneda, Chitose, Osaka, Fukuoka and Miyazaki. Finally, the community reaction to aircraft noise was compared with the reaction to road traffic noise and train noise. The rates of annoyance and speech interference were highly dependent on noise levels. Other relevant factors, such as sex, age, year of residence, occupation, etc., had much weaker relations to the extent of reactions.

  11. Modelling Psychological Responses to the Great East Japan Earthquake and Nuclear Incident

    PubMed Central

    Goodwin, Robin; Takahashi, Masahito; Sun, Shaojing; Gaines, Stanley O.

    2012-01-01

    The Great East Japan (Tōhoku/Kanto) earthquake of March 2011was followed by a major tsunami and nuclear incident. Several previous studies have suggested a number of psychological responses to such disasters. However, few previous studies have modelled individual differences in the risk perceptions of major events, or the implications of these perceptions for relevant behaviours. We conducted a survey specifically examining responses to the Great Japan earthquake and nuclear incident, with data collected 11–13 weeks following these events. 844 young respondents completed a questionnaire in three regions of Japan; Miyagi (close to the earthquake and leaking nuclear plants), Tokyo/Chiba (approximately 220 km from the nuclear plants), and Western Japan (Yamaguchi and Nagasaki, some 1000 km from the plants). Results indicated significant regional differences in risk perception, with greater concern over earthquake risks in Tokyo than in Miyagi or Western Japan. Structural equation analyses showed that shared normative concerns about earthquake and nuclear risks, conservation values, lack of trust in governmental advice about the nuclear hazard, and poor personal control over the nuclear incident were positively correlated with perceived earthquake and nuclear risks. These risk perceptions further predicted specific outcomes (e.g. modifying homes, avoiding going outside, contemplating leaving Japan). The strength and significance of these pathways varied by region. Mental health and practical implications of these findings are discussed in the light of the continuing uncertainties in Japan following the March 2011 events. PMID:22666380

  12. 9 CFR 94.27 - Importation of whole cuts of boneless beef from Japan.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... beef from Japan. 94.27 Section 94.27 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION... IMPORTATIONS § 94.27 Importation of whole cuts of boneless beef from Japan. Notwithstanding any other... slaughtered in Japan may be imported into the United States under the following conditions: (a) The beef is...

  13. Troubled Partnership. An Assessment of U.S.-Japan Collaboration on the FS-X Fighter,

    DTIC Science & Technology

    1995-01-01

    Technology Transfer and Flowback 32 Commercial Spinoffs to Japan Exaggerated 33 Emphasis on Technology Flowback from Japan Was Political...take part in the development of the FS-X, and en- sure flowback of Japanese technology to the United States. In return, Japan paid $60 million to LFWC...involved flowback and access to Japanese technology. The government agreements stipulated that Japan would provide all technology applied to the FS-X

  14. Astrocytes potentiate GABAergic transmission in the thalamic reticular nucleus via endozepine signaling.

    PubMed

    Christian, Catherine A; Huguenard, John R

    2013-12-10

    Emerging evidence indicates that diazepam-binding inhibitor (DBI) mediates an endogenous benzodiazepine-mimicking (endozepine) effect on synaptic inhibition in the thalamic reticular nucleus (nRT). Here we demonstrate that DBI peptide colocalizes with both astrocytic and neuronal markers in mouse nRT, and investigate the role of astrocytic function in endozepine modulation in this nucleus by testing the effects of the gliotoxin fluorocitrate (FC) on synaptic inhibition and endozepine signaling in the nRT using patch-clamp recordings. FC treatment reduced the effective inhibitory charge of GABAA receptor (GABAAR)-mediated spontaneous inhibitory postsynaptic currents in WT mice, indicating that astrocytes enhance GABAAR responses in the nRT. This effect was abolished by both a point mutation that inhibits classical benzodiazepine binding to GABAARs containing the α3 subunit (predominant in the nRT) and a chromosomal deletion that removes the Dbi gene. Thus, astrocytes are required for positive allosteric modulation via the α3 subunit benzodiazepine-binding site by DBI peptide family endozepines. Outside-out sniffer patches pulled from neurons in the adjacent ventrobasal nucleus, which does not contain endozepines, show a potentiated response to laser photostimulation of caged GABA when placed in the nRT. FC treatment blocked the nRT-dependent potentiation of this response, as did the benzodiazepine site antagonist flumazenil. When sniffer patches were placed in the ventrobasal nucleus, however, subsequent treatment with FC led to potentiation of the uncaged GABA response, suggesting nucleus-specific roles for thalamic astrocytes in regulating inhibition. Taken together, these results suggest that astrocytes are required for endozepine actions in the nRT, and as such can be positive modulators of synaptic inhibition.

  15. Astrocytes potentiate GABAergic transmission in the thalamic reticular nucleus via endozepine signaling

    PubMed Central

    Christian, Catherine A.; Huguenard, John R.

    2013-01-01

    Emerging evidence indicates that diazepam-binding inhibitor (DBI) mediates an endogenous benzodiazepine-mimicking (endozepine) effect on synaptic inhibition in the thalamic reticular nucleus (nRT). Here we demonstrate that DBI peptide colocalizes with both astrocytic and neuronal markers in mouse nRT, and investigate the role of astrocytic function in endozepine modulation in this nucleus by testing the effects of the gliotoxin fluorocitrate (FC) on synaptic inhibition and endozepine signaling in the nRT using patch-clamp recordings. FC treatment reduced the effective inhibitory charge of GABAA receptor (GABAAR)-mediated spontaneous inhibitory postsynaptic currents in WT mice, indicating that astrocytes enhance GABAAR responses in the nRT. This effect was abolished by both a point mutation that inhibits classical benzodiazepine binding to GABAARs containing the α3 subunit (predominant in the nRT) and a chromosomal deletion that removes the Dbi gene. Thus, astrocytes are required for positive allosteric modulation via the α3 subunit benzodiazepine-binding site by DBI peptide family endozepines. Outside-out sniffer patches pulled from neurons in the adjacent ventrobasal nucleus, which does not contain endozepines, show a potentiated response to laser photostimulation of caged GABA when placed in the nRT. FC treatment blocked the nRT-dependent potentiation of this response, as did the benzodiazepine site antagonist flumazenil. When sniffer patches were placed in the ventrobasal nucleus, however, subsequent treatment with FC led to potentiation of the uncaged GABA response, suggesting nucleus-specific roles for thalamic astrocytes in regulating inhibition. Taken together, these results suggest that astrocytes are required for endozepine actions in the nRT, and as such can be positive modulators of synaptic inhibition. PMID:24262146

  16. Nucleus reticularis neurons mediate diverse inhibitory effects in thalamus.

    PubMed

    Cox, C L; Huguenard, J R; Prince, D A

    1997-08-05

    Detailed information regarding the contribution of individual gamma-aminobutyric acid (GABA)-containing inhibitory neurons to the overall synaptic activity of single postsynaptic cells is essential to our understanding of fundamental elements of synaptic integration and operation of neuronal circuits. For example, GABA-containing cells in the thalamic reticular nucleus (nRt) provide major inhibitory innervation of thalamic relay nuclei that is critical to thalamocortical rhythm generation. To investigate the contribution of individual nRt neurons to the strength of this internuclear inhibition, we obtained whole-cell recordings of unitary inhibitory postsynaptic currents (IPSCs) evoked in ventrobasal thalamocortical (VB) neurons by stimulation of single nRt cells in rat thalamic slices, in conjunction with intracellular biocytin labeling. Two types of monosynaptic IPSCs could be distinguished. "Weak" inhibitory connections were characterized by a significant number of postsynaptic failures in response to presynaptic nRt action potentials and relatively small IPSCs. In contrast, "strong" inhibition was characterized by the absence of postsynaptic failures and significantly larger unitary IPSCs. By using miniature IPSC amplitudes to infer quantal size, we estimated that unitary IPSCs associated with weak inhibition resulted from activation of 1-3 release sites, whereas stronger inhibition would require simultaneous activation of 5-70 release sites. The inhibitory strengths were positively correlated with the density of axonal swellings of the presynaptic nRt neurons, an indicator that characterizes different nRt axonal arborization patterns. These results demonstrate that there is a heterogeneity of inhibitory interactions between nRt and VB neurons, and that variations in gross morphological features of axonal arbors in the central nervous system can be associated with significant differences in postsynaptic response characteristics.

  17. Candidates of World Heritage Sites of Astronomy in Japan

    NASA Astrophysics Data System (ADS)

    Watanabe, Jun-ichi; Nakagiri, Masao

    2015-08-01

    Unfortunately there is no heritage site of astronomy until now in Japan. Here we report several candidates based on the importance from the historical point of view.One is the “Nisshinkan” Astronomical Observatory site of the Edo era. Many observatories were established in the Edo era, including "Asakusa observatory" of a Shogunate Government. However, most of them have been disappeared by the urban development. The only one remained until now is the “Nissshinkan” Astronomical Observatory site of which the basement made of stones is preserved. This was made in 1803 mainly for educational purpose at the “Nisshinkan” which was a local school for the Samurai’s children in Aizu area. Although a wooden building of the school was lost by a war, but this observatory mark exists because large basement of a few meters high remained. This site is now designated as a cultural asset by the local government, and can be recognized even at the present time.Another is the Repsold Meridian Transit which was designated as the Important Cultural Property of Japan in 2011. A Repsold meridian transit instrument is a telescope with a diameter of 13.5 cm and a focal length of 212 cm for meridian transit observations. It was manufactured by A. Repsold & Soehne Co. Ltd. in Hamburg, Germany in 1880, and purchased by the Naval Observatory and imported to Japan in 1881, becoming one of the most important telescopes in the dawning era of modern astronomy in Japan. The telescope escaped being damaged in the Great Kanto Earthquake, and continued to be used as a main telescope for time determination, longitude observation, and astrometry of heavenly bodies till the end of the 1950s. We confirmed that this telescope has retained its original form in 2008, and after restoration and repair, the telescope was widely opened for exhibition to the public. In June, 2011 it was designated as one of the important cultural properties of Japan. The related old instruments which brought modern

  18. In Search of Mutual Understanding: A Classroom Approach to Japan.

    ERIC Educational Resources Information Center

    Indiana Univ., Bloomington. Social Studies Development Center.

    An activity book is designed to address problems and oversights in classroom coverage of Japan discovered by the Japan/United States Textbook Study Project. Activities which focus on Japanese religion, language, and geography address two important questions: what immediate application does the textbook study have for classroom teachers and how can…

  19. DNA types of aspermic Fasciola species in Japan.

    PubMed

    Ichikawa, Madoka; Iwata, Noriyuki; Itagaki, Tadashi

    2010-10-01

    In order to reveal DNA types of aspermic Fasciola forms in Japan, Fasciola specimens obtained from eight prefectures that had not been previously reported were analyzed for DNA of ribosomal internal transcribed spacer 1 (ITS1) and mitochondrial NADH dehydrogenase 1 (ND1) gene. Five combinations in DNA types of both ITS1 and ND1 were revealed from the results of this study and previous studies. The DNA type Fsp2, which is identical to that of F. gigantica in both ITS1 and ND1, was the most predominant in Japan, followed by Fsp1, which is the same DNA type as that of F. hepatica. Fasciola forms with Fsp1 mainly occurred in the northern region of Japan and those with Fsp2 were mainly in the western region. The founder effect related to migration of definitive host and susceptibility of intermediate host snail might play an important role in both geographical distribution and frequency of DNA types in Japanese Fasciola specimens.

  20. Satellite Radar Measures Tohoku, Japan Earthquake

    NASA Image and Video Library

    2011-04-01

    This radar image, called a coseismic interferogram, using satellite data from the European Space Agency Envisat depicts ground displacements resulting from the March 11, 2011, magnitude 9.0 Tohoku earthquake in Japan.

  1. 77 FR 23508 - Brass Sheet and Strip From France, Germany, Italy, and Japan

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-19

    ...)] Brass Sheet and Strip From France, Germany, Italy, and Japan Determination On the basis of the record \\1... antidumping duty orders on brass sheet and strip from France, Germany, Italy, and Japan would be likely to... from France, Germany, Italy, and Japan: Investigation Nos. 731-TA-313, 314, 317, and 379 (Third Review...

  2. Medication Guide

    MedlinePlus

    ... before starting any new medication. First-Line Medications: Nicotine Replacement Therapy (NRT) These medications are called "first- ... they might try a "second-line" medication instead. Nicotine replacement therapy (NRT) helps smokers quit by reducing ...

  3. Thermophotovoltaic systems for civilian and industrial applications in Japan

    NASA Astrophysics Data System (ADS)

    Yugami, Hiroo; Sasa, Hiromi; Yamaguchi, Masafumi

    2003-05-01

    The potential market for thermophotovoltaic (TPV) applications has been studied for civilian and industrial sectors in Japan. Comparing the performance of gas engines or turbines, as well as the underdeveloped power generation technologies such as fuel cells or chemical batteries, we have discussed the feasible application field of TPV systems to compete with those power generations. From the point of view of applicability for TPV systems in Japan, portable generators, co-generation systems and solar power plants are selected for our system analysis. The cost and performance targets of TPV systems for co-generation are also discussed by assuming a typical daily profile of electricity and hot water demands in Japanese homes. A progress report on the recent TPV research activities is given as well as a feasibility study concerning such TPV systems in Japan.

  4. Atmospheric short-chain chlorinated paraffins in China, Japan, and South Korea.

    PubMed

    Li, Qilu; Li, Jun; Wang, Yan; Xu, Yue; Pan, Xiaohui; Zhang, Gan; Luo, Chunling; Kobara, Yuso; Nam, Jae-Jak; Jones, Kevin C

    2012-11-06

    This study presents the first investigation of concentrations and congener group patterns of atmospheric short-chain chlorinated paraffins (SCCPs) throughout East Asia. Based on an absorption rate calibration experiment, a spatial survey of SCCPs was performed using passive air samplers in China, Japan, and South Korea during two separate periods in 2008. The atmospheric concentrations of SCCPs in China were clearly greater than those in Japan and South Korea, both of which exceed the levels determined for other regions of the world. C(10) components were the most abundant type of SCCPs in China, whereas C(11) components were dominant in Japan and South Korea. With respect to the total chlorine content, Cl(6) and Cl(5) were the predominant compounds in China and Japan; however, Cl(6) and Cl(7) were predominant in South Korea. A similar pattern was also found for remote sites within China, Japan, and South Korea, respectively. Together with the back-trajectories calculated for the remote sites, the results indicate that the SCCPs in the air of East Asia were mainly influenced by local sources due to their relatively low long-range atmospheric transport potential compared to other POPs.

  5. The Japan of Today, 1982.

    ERIC Educational Resources Information Center

    Ministry of Foreign Affairs, Tokyo (Japan).

    Following an introduction which discusses the history and geography of Japan, this book focuses on topics related to this country's government, economy, social conditions, and cultural life. Topics related to government include: constitution and emperor; legislature; executive power; judiciary system; foreign relations; and defense. Topics related…

  6. Psychological distress during pregnancy in Miyagi after the Great East Japan Earthquake: The Japan Environment and Children's Study.

    PubMed

    Watanabe, Zen; Iwama, Noriyuki; Nishigori, Hidekazu; Nishigori, Toshie; Mizuno, Satoshi; Sakurai, Kasumi; Ishikuro, Mami; Obara, Taku; Tatsuta, Nozomi; Nishijima, Ichiko; Fujiwara, Ikuma; Nakai, Kunihiko; Arima, Takahiro; Takeda, Takashi; Sugawara, Junichi; Kuriyama, Shinichi; Metoki, Hirohito; Yaegashi, Nobuo

    2016-01-15

    To examine psychological distress among pregnant women in Miyagi prefecture which was directly affected by the Great East Japan Earthquake and tsunami and compare other areas of Japan that were less damaged. This study was conducted in conjunction with the Japan Environment and Children's Study (JECS). We examined 10,129 Japanese women using the primary fixed data of the JECS. The Kessler 6-item psychological distress scale (K6) was administered to 7473 eligible women including 998 in Miyagi unit center ('Miyagi UC') and 6475 in the other unit centers ('13UCs'). We compared the prevalence and the risk of distress (K6 ≥ 13) during pregnancy in 'Miyagi UC' and '13UCs'. More women in 'Miyagi UC' (4.9%) suffered psychological distress, compared with '13UCs' (3.1%) (p<0.001). A significantly higher prevalence of women in 'Miyagi UC' (55.5%) had experienced negative life events, whereas '13UCs' showed 42.7% (p<0.0001). In multivariable logistic analyses adjusted for baseline characteristics, there was a significant regional difference of psychological distress (adjusted odds ratio; aOR in Miyagi UC=1.488; 95%CI, 1.059-2.090). After further adjusting for negative life events, the association was diminished (aOR=1.338; 95%CI, 0.949-1.884). The JECS had no data before the earthquake and the extent of damage was not investigated. Possible regional representativeness is also a limitation. After the Great East Japan Earthquake, the prevalence of pregnant women with psychological distress (K6 ≥ 13) were high in Miyagi prefecture. Especially in the coastal area directly affected by tsunami, it is high with or without negative life events experienced. Copyright © 2015 Elsevier B.V. All rights reserved.

  7. Novel delivery systems for nicotine replacement therapy as an aid to smoking cessation and for harm reduction: rationale, and evidence for advantages over existing systems.

    PubMed

    Shahab, Lion; Brose, Leonie S; West, Robert

    2013-12-01

    Nicotine replacement therapy (NRT) has been used in the treatment of tobacco dependence for over three decades. Whilst the choice of NRT was limited early on, in the last ten years there has been substantial increase in the number of nicotine delivery devices that have become available. This article briefly summarises existing forms of NRT, evidence of their efficacy and use, and reviews the rationale for the development of novel products delivering nicotine via buccal, transdermal or pulmonary routes (including nicotine mouth spray, nicotine films, advanced nicotine inhalers and electronic cigarettes). It presents available evidence on the efficacy, tolerability and abuse potential of these products, with a focus on their advantages as well as disadvantages compared with established forms of NRT for use as an aid to both smoking cessation as well as harm reduction.

  8. English education for healthcare professionals in Japan.

    PubMed

    Moross, Janelle; Seki, Naoko; Morio, Ikuko

    2017-11-01

    In a global environment, education for healthcare professionals should include cultivating human resources who have the necessary skills to work in an international arena. This article will review the current status of English education for dental healthcare professionals in Japan. After conducting a literature search using the keywords: English education, Japan, and dental, only a few studies were found that investigated and proposed suggestions for dental professional English education. Even so, these were still in the early stages with outcomes yet to be fully evaluated. Even though English is thought indispensable for global professionals, and that increasing chances for communication skills is necessary, little attention has been addressed to English education for dental professionals or the implementation of such education in the Japanese undergraduate dental curricula. With the current reality of field expansion in dentistry, the need for not only improved English communication skills for Japanese dentists, but also the acquisition of essential expertise, psychomotor, teambuilding, critical thinking, and creative thinking skills in English as well as Japanese, is a definite probability. In order to reach this level of knowledge, further efforts and research would be necessary for the advancement and development of dental professional English education in Japan.

  9. Child Abuse and Neglect in Japan: Coin-Operated-Locker Babies.

    ERIC Educational Resources Information Center

    Kouno, Akihisa; Johnson, Charles F.

    1995-01-01

    This paper reviews Japan's child abuse/neglect history, including the incidence of "coin-operated-locker babies," where murdered infants are hidden in railway and airport lockers, and actions taken to reduce this problem. The incidence of child abuse in Japan and the United States is compared, and social influences on the number of…

  10. Perceptions of Aging and Disability among College Students in Japan

    ERIC Educational Resources Information Center

    Warren, Nicholas J.; Kamimura, Akiko; Trinh, Ha Ngoc; Stephens, Emily; Omi, Keita; Kanaoka, Ana; Ishikawa, Ai; Yamanaka, Katsuo

    2015-01-01

    Japan launched the Long-term Care Insurance program in 2000, and ratified the United Nations' Convention on the Rights of Persons with Disabilities in 2014. Japan has been taking significant steps to support their elderly population and individuals with disabilities. However, information is lacking on the understanding and opinions of either of…

  11. Rotarix in Japan: Expectations and Concerns.

    PubMed

    Nakagomi, Osamu; Nakagomi, Toyoko

    2011-01-01

    A live-attenuated, orally-administered, monovalent, human rotavirus vaccine, Rotarix® (GlaxoSmithKline Biologicals, Rixensart, Belgium), was licensed and launched in 2011 as the first rotavirus vaccine in Japan. The rotavirus causes a substantial disease burden with an estimated 790,000 outpatient visits, 27,000-78,000 hospitalizations, and approximately 10 deaths each year in Japan. Since a recent clinical trial showed that Rotarix was as efficacious in Japan as in other industrialized countries, it is expected that the annual number of rotavirus hospitalizations will be reduced to between 1000-3000, and that outpatient visits will be reduced to 200,000. The universal rotavirus immunization program with Rotarix was calculated to be at the threshold of being cost-effective, even from the healthcare perspective, and it was highly cost-effective from the societal perspective, assuming that Rotarix is co-administered with other childhood vaccines. While Rotarix contains only a single G1P[8] human rotavirus, the postlicensure studies in Brazil showed that Rotarix provided a 75%-85% protective efficacy against severe dehydrating diarrhea or hospitalizations due to fully-heterotypic G2P[4] strains. While postlicensure studies detected a small and finite risk of intussusception associated with the administration of Rotarix, the authors conclude that Rotarix is safe to administer to infants between 6-12 weeks of age for the first dose and by 24 weeks of age for the second dose. However, the authors strongly discourage the delayed administration of the first dose between 13-20 weeks of age, which is allowed without any warning. Given the high incidence of naturally-occurring intussusception in Japan (185 cases per 100,000 children/year among children less than 1 year of age), this should prevent pediatricians and parents from having ill-perceptions of Rotarix being associated with an increased number of temporally-associated intussusception, and fully appreciate the

  12. [Beginning Knowledge of Transfusion in Japan].

    PubMed

    Mazda, Toshio; Shimizu, Masaru

    2015-01-01

    Blood components and plasma derivatives are two of the most useful tools in modern medicine. When the Portuguese opened the maritime routes to the Far East in the 16th century. Western medicine traveled to Japan on the trading vessels that carried physicians and barber-surgeons to care for the body and Christian missionaries to care for the soul. Skilled interpreters such as Kōgyū Yoshio translated and studied Dutch editions of early medical books, like Lorenz Heister's "Chirurgie" (Nürnberg, 1719), that illustrate the concept of transfusion. The oldest description of transfusion originating in Japan is a handwritten manuscript entitled "Bansui Sensi Chojutsu Shomoku" by Masamichi Nishijima, a student of Bansui Otsuki. It is a list of Otsuki's translated works. He described book names and chapter names in the manuscript, and when he finished translation of a chapter, he marked a circle on the chapter name. The transfusion chapter had a circle. That dates the earliest writing on transfusion in Japanese to 1804, shortly after the death of Kōgyū. Unfortunately, the manuscript translation no longer exists. In 1814, Shunzō Yoshio, grandson of Kōgyū, and in 1820, Tokki Koshimura, translated the figure legends of "Chirurgie." Soon afterwards, after the first report of transfusion from human-to-human by James Blundell in London in 1818, Western medical books published on the subject began to arrive. The works of Christoph Wilhelm Hufeland, Georg Friedrich Most and Carl Canstatt all mentioning transfusion, albeit without details, were translated by Kōan Ogata and Shinryō Tsuboi. During the Edo period, Japan was a closed country; only open to the Dutch through a tiny island in Nagasaki. But Japanese doctors in the Edo period learned about blood transfusion through Dutch-translated versions of Western medical Books. Transfusion began being practiced in Japan in 1919, almost exactly 100 years after the concept was introduced

  13. Japan's telecommunications - New initiatives in space communications

    NASA Astrophysics Data System (ADS)

    Iida, T.

    1992-04-01

    Despite recent advances in optical transmission technology, intensive R&D work in the field of satellite communications is now being undertaken in Japan. It is believed that satellites offer advantages in several important areas, including wide coverage broadcasting, immediacy of service, suitability for the implementation of HDTV, and advantages in disaster communications and other social services. Here, some experimental projects in the field of satellite communications planned in Japan for the 1990s are summarized. In particular, attention is given to broadcast satellite development, intersatellite links, advanced mobile communication concepts, large antenna assembly experiment, small satellite R&D, and Pan-Pacific information network experiment.

  14. Sleep characteristics of young children in Japan: internet study and comparison with other Asian countries.

    PubMed

    Kohyama, Jun; Mindell, Jodi A; Sadeh, Avi

    2011-10-01

    A recent international Internet-based study of young children (birth to 36 months) found that total sleep duration in Japan was the shortest among 17 countries/regions. The present study compared features of children's sleep in Japan relative to those in other Asian countries/regions. Parents of 872 infants and toddlers in Japan (48.6% boys), and parents of 20 455 infants and toddlers in 11 other Asian countries/regions (48.1% boys; China, Hong Kong, India, Indonesia, Korea, Malaysia, Philippines, Singapore, Taiwan, Thailand, and Vietnam) completed an Internet-based expanded version of the Brief Infant Sleep Questionnaire. Young children in Japan exhibited significantly fewer nocturnal wakings and shorter daytime sleep in comparison with other Asian countries/regions. Although the former finding was apparent in all age groups, the reduced duration of daytime sleep in Japan was not present until after 3 months of age. Interestingly, sleep problems were reported by significantly fewer parents in Japan compared with those in other Asian countries/regions, although parents in Japan reported significantly more difficulty at bedtime. The short sleep duration of young children in Japan is largely due to a relatively short duration of daytime sleep. Significant differences in sleep characteristics in Japan relative to other Asian regions were found primarily after 3 months of age. Future studies should further explore the underlying causes and the potential impacts of these sleep differences. © 2011 The Authors. Pediatrics International © 2011 Japan Pediatric Society.

  15. Suicide among foreign residents of Japan.

    PubMed

    Lester, David; Saito, Yukio; Ben Park, B C

    2011-02-01

    The suicide rate of Koreans living in Japan is twice as high as that of Koreans in South Korea. Reasons for this high suicide rate are discussed, including effects of economic crises and discrimination.

  16. 7 CFR 319.56-27 - Apples from Japan and the Republic of Korea.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 5 2014-01-01 2014-01-01 false Apples from Japan and the Republic of Korea. 319.56-27... § 319.56-27 Apples from Japan and the Republic of Korea. Any variety of Malus domestica apples may be imported into the United States from Japan, and Fuji variety apples may be imported into the United States...

  17. 7 CFR 319.56-27 - Apples from Japan and the Republic of Korea.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 5 2012-01-01 2012-01-01 false Apples from Japan and the Republic of Korea. 319.56-27... § 319.56-27 Apples from Japan and the Republic of Korea. Any variety of Malus domestica apples may be imported into the United States from Japan, and Fuji variety apples may be imported into the United States...

  18. 7 CFR 319.56-27 - Apples from Japan and the Republic of Korea.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 5 2013-01-01 2013-01-01 false Apples from Japan and the Republic of Korea. 319.56-27... § 319.56-27 Apples from Japan and the Republic of Korea. Any variety of Malus domestica apples may be imported into the United States from Japan, and Fuji variety apples may be imported into the United States...

  19. 7 CFR 319.56-27 - Apples from Japan and the Republic of Korea.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 5 2011-01-01 2011-01-01 false Apples from Japan and the Republic of Korea. 319.56-27... § 319.56-27 Apples from Japan and the Republic of Korea. Any variety of Malus domestica apples may be imported into the United States from Japan, and Fuji variety apples may be imported into the United States...

  20. Upper Ocean Measurements of Water Masses and Circulation in the Japan Sea

    DTIC Science & Technology

    2003-09-30

    Japan Sea via Tsugaru Strait into the N. Pacific and through Soya Strait into the Okhotsk Sea. On float entered the Okhotsk Sea through Soya Strait and...Riser (2003) Connections between the Japan Sea and Okhotsk Sea through Soya Strait. Submitted to Journal of Geophysical Research. Riser, S., M...PUBLICATIONS Danchenkov, M. and S. Riser (2003) Connections between the Japan Sea and Okhotsk Sea through Soya Strait. Submitted to Journal of Geophysical

  1. 22 CFR 126.14 - Special comprehensive export authorizations for NATO, Australia, Japan, and Sweden.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... NATO, Australia, Japan, and Sweden. 126.14 Section 126.14 Foreign Relations DEPARTMENT OF STATE... authorizations for NATO, Australia, Japan, and Sweden. (a) Comprehensive authorizations. With respect to NATO members, Australia, Japan, and Sweden, the Directorate of Defense Trade Controls may provide the...

  2. 22 CFR 126.14 - Special comprehensive export authorizations for NATO, Australia, Japan, and Sweden.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... NATO, Australia, Japan, and Sweden. 126.14 Section 126.14 Foreign Relations DEPARTMENT OF STATE... authorizations for NATO, Australia, Japan, and Sweden. (a) Comprehensive authorizations. With respect to NATO members, Australia, Japan, and Sweden, the Directorate of Defense Trade Controls may provide the...

  3. 22 CFR 126.14 - Special comprehensive export authorizations for NATO, Australia, Japan, and Sweden.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... NATO, Australia, Japan, and Sweden. 126.14 Section 126.14 Foreign Relations DEPARTMENT OF STATE... authorizations for NATO, Australia, Japan, and Sweden. (a) Comprehensive authorizations. With respect to NATO members, Australia, Japan, and Sweden, the Directorate of Defense Trade Controls may provide the...

  4. Characteristics of hospital-based Munchausen Syndrome by Proxy in Japan.

    PubMed

    Fujiwara, Takeo; Okuyama, Makiko; Kasahara, Mari; Nakamura, Ayako

    2008-04-01

    This article explores characteristics of Munchausen Syndrome by Proxy (MSBP) in Japan, a country which provides an egalitarian, low cost, and easy-access health care system. We sent a questionnaire survey to 11 leading doctors in the child abuse field in Japan, each located in different hospital-based sites. Child abuse doctors answered questions regarding the characteristics of MSBP cases for whom they had helped care. Twenty-one MSBP cases (20 families) were reported. Characteristics of the victims included: no differences based on sex, 4.6 years of age on average when MSBP was confirmed, and an average of 1.9 years duration of MSBP abuse. Biological mothers were at least one of the perpetrators in 95% of cases. Among the 12 cases (57%) who remained with their families, 2 victims died. Only 5% of perpetrators had a medical background or relatives who engaged in healthcare work. There are similar features of MSBP cases between Japan and other English-speaking countries, such as the UK or the US. However, perpetrators of MSBP in Japan did not have a medical background. Easier access to hospital resources in Japan may give greater opportunities for perpetrators to obtain medical knowledge from doctors or nurses. The findings suggest that perpetrators of MSBP should not be assumed to possess a medical background in a country which provides universal medical care such as Japan. A contributory factor of MSBP may be the high frequency of medical consultations and equal level of accessibility of medical resources for Japanese citizens. Social welfare services that need to decide on custody for MSBP victims should recognize the relatively high risk of life-threatening danger in their family of origin. Further collaboration between hospital staff including pediatricians, nurses, medical social workers and staff at the social welfare services is needed to protect children from MSBP.

  5. Japan Diabetic Nephropathy Cohort Study: study design, methods, and implementation.

    PubMed

    Furuichi, Kengo; Shimizu, Miho; Toyama, Tadashi; Koya, Daisuke; Koshino, Yoshitaka; Abe, Hideharu; Mori, Kiyoshi; Satoh, Hiroaki; Imanishi, Masahito; Iwano, Masayuki; Yamauchi, Hiroyuki; Kusano, Eiji; Fujimoto, Shouichi; Suzuki, Yoshiki; Okuda, Seiya; Kitagawa, Kiyoki; Iwata, Yasunori; Kaneko, Shuichi; Nishi, Shinichi; Yokoyama, Hitoshi; Ueda, Yoshihiko; Haneda, Masakazu; Makino, Hirofumi; Wada, Takashi

    2013-12-01

    Diabetic nephropathy, leading to end-stage renal disease, has a considerable impact on public health and the social economy. However, there are few national registries of diabetic nephropathy in Japan. The aims of this prospective cohort study are to obtain clinical data and urine samples for revising the clinical staging of diabetic nephropathy, and developing new diagnostic markers for early diabetic nephropathy. The Japanese Society of Nephrology established a nationwide, web-based, and prospective registry system. On the system, there are two basic registries; the Japan Renal Biopsy Registry (JRBR), and the Japan Kidney Disease Registry (JKDR). In addition to the two basic registries, we established a new prospective registry to the system; the Japan Diabetic Nephropathy Cohort Study (JDNCS), which collected physical and laboratory data. We analyzed the data of 321 participants (106 female, 215 male; average age 65 years) in the JDNCS. Systolic and diastolic blood pressure was 130.1 and 72.3 mmHg, respectively. Median estimated glomerular filtration rate (eGFR) was 33.3 ml/min/1.73 m(2). Proteinuria was 1.8 g/gCr, and serum levels of albumin were 3.6 g/dl. The majority of the JDNCS patients presented with preserved eGFR and low albuminuria or low eGFR and advanced proteinuria. In the JRBR and JKDR registries, 484 and 125 participants, respectively, were enrolled as having diabetes mellitus. In comparison with the JRBR and JKDR registries, the JDNCS was characterized by diabetic patients presenting with low proteinuria with moderately preserved eGFR. There are few national registries of diabetic nephropathy to evaluate prognosis in Japan. Future analysis of the JDNCS will provide clinical insights into the epidemiology and renal and cardiovascular outcomes of type 2 diabetic patients in Japan.

  6. Characteristics of Hospital-Based Munchausen Syndrome by Proxy in Japan

    ERIC Educational Resources Information Center

    Fujiwara, Takeo; Okuyama, Makiko; Kasahara, Mari; Nakamura, Ayako

    2008-01-01

    Objective: This article explores characteristics of Munchausen Syndrome by Proxy (MSBP) in Japan, a country which provides an egalitarian, low cost, and easy-access health care system. Methods: We sent a questionnaire survey to 11 leading doctors in the child abuse field in Japan, each located in different hospital-based sites. Child abuse doctors…

  7. English, Language Shift and Values Shift in Japan and Singapore

    ERIC Educational Resources Information Center

    Morita, Liang

    2015-01-01

    This is a comparative study of English language education in Japan and Singapore and the role English plays in both countries. English language education in Japan has not been very effective. Although the communicative approach to teaching English was introduced in the 1980s, schools still use the grammar-translation method and most Japanese do…

  8. Tora no Maki III. Lessons for Teaching about Contemporary Japan.

    ERIC Educational Resources Information Center

    National Council for the Social Studies, Washington, DC.

    The elements of Japan, including history, geography, economics, civics, and cultural studies, are in this collection of original lesson plans. The lessons are meant to provide original content about Japan to augment and supplement an existing unit of study and evoke a spirit of inquiry and introspection. The 24 lessons are as follows: (1)…

  9. Calibration between the Estimated Probability of the Risk Assessment Chart of Japan Atherosclerosis Society and Actual Mortality Using External Population: Evidence for Cardiovascular Prevention from Observational Cohorts in Japan (EPOCH-JAPAN).

    PubMed

    Nakai, Michikazu; Miyamoto, Yoshihiro; Higashiyama, Aya; Murakami, Yoshitaka; Nishimura, Kunihiro; Yatsuya, Hiroshi; Saitoh, Shigeyuki; Sakata, Kiyomi; Iso, Hiroyasu; Miura, Katsuyuki; Ueshima, Hirotsugu; Okamura, Tomonori

    2016-01-01

    In Japan Atherosclerosis Society guidelines for the prevention of atherosclerotic cardiovascular diseases 2012 (JAS2012), NIPPON DATA80 risk assessment chart (ND80RAC) was adopted to estimate the 10-year probability of coronary artery disease (CAD) mortality. However, there was no comparison between the estimated mortality calculated by ND80RAC and actual mortality in external populations. Accordingly, we used the large pooled database of cohorts in Japan, EPOCH-JAPAN, as an external population. The participants of EPOCH-JAPAN without a history of cardiovascular disease (15,091 men and 18,589 women aged 40-74 years) were analyzed based on sex. The probability of a 10-year risk of CAD/stroke mortality was estimated by ND80RAC. The participants were divided into both decile of their estimated mortality and three categories according to JAS2012. The calibration between the mean estimated mortality and the actual mortality was performed by the Hosmer and Lemeshow (H-L) test. In both sexes, the estimated CAD mortality was higher than the actual mortality, particularly in higher deciles of estimated mortality, and the estimated stroke mortality was almost concordant with the actual mortality in low/moderate deciles of estimated mortality. As for the categories according to JAS2012, the estimated CAD mortality was higher than the actual mortality in both sexes; actual mortality in Category III was lower than that in Category II in women. However, it increased in the ascending order of category when we excluded the presence of diabetes from Category III. The estimated CAD mortality by ND80RAC tended to be higher than the actual mortality in the population in which the baseline survey was more recently performed.

  10. Mentorship as Experienced by Women Surgeons in Japan.

    PubMed

    Yorozuya, Kyoko; Kawase, Kazumi; Akashi-Tanaka, Sadako; Kanbayashi, Chizuko; Nomura, Sachiyo; Tomizawa, Yasuko

    2016-01-01

    Women have accounted for over 30% of new medical students since 1995 in Japan. Establishing support systems for women surgeons to continue their work is a major issue in Japan. Mentorship can be one of the most effective means to help women surgeons to continue their work. The purpose of this study was to clarify the current status of mentorship among Japanese women surgeons and to discuss the role of mentors for women surgeons. Invitation letters were sent to all female members of the Japan Association of Women Surgeons in April 2011. An 84-item questionnaire survey was sent to those who agreed to participate in this study via the internet. Fifty-five surgeons participated in this study, a response rate of 48.7%. Sixty-seven percent of respondents found it difficult to continue in their job; 85% thought mentorship was necessary for women surgeons to progress in their careers; and 84% reported that they already had a mentor. Respondents thought that a mentor helped them to advance their clinical career, to stay in their job, and to provide moral support. However, mentors appeared to be less useful in helping them to advance their research career, to network, to increase their status, and to achieve a work-life balance. This study revealed areas where mentors appeared to be less helpful to women surgeons. The survey gave an indication of how to help improve and develop the career and personal life of women surgeons in Japan.

  11. In Defense of Japan

    DTIC Science & Technology

    2018-01-03

    national elections. The party majority gives Abe the potential to formally amend Article 9 of the Japanese constitution to authorize the Japanese Self ...Pacific. Japanese Constitution; Article 9; The United States and Japan Bi-lateral defense treaty; Collective Self Defense; Pacifism; Japanese Self ...involvement in collective self -defense (CSD). Factors leading up to this decision are a rapidly evolving strategic and political environment in

  12. Pharmaceutical pricing in Japan: market evidence for rheumatoid arthritis treatment.

    PubMed

    Mahlich, Jörg; Kamae, Isao; Sruamsiri, Rosarin

    2018-06-01

    Drug price setting is one of the key challenges faced by the Japanese health care system. This study aims to identify the determinants of drug price in Japan using the example of the rheumatoid arthritis (RA) treatment market. In order to compare prices across different products, we calculated prices per defined daily dose using WHO methodology. Price determinants were calculated both at launch and over time using IMS quarterly data on medicines approved for RA treatment in Japan from 2012 to 2015. Pharmaceutical pricing was modeled as a function of clinical and economic variables using regression analysis. For prices at the launch we found that differences in efficacy are not reflected in price differentials. We also report that the number of products within a molecule class had a negative effect on prices while originator drugs maintained higher prices. Although the existing pricing rules in Japan are very comprehensive they do not necessarily capture differences in product characteristics. The findings here support the notion that competitive forces are weak in highly regulated markets such as Japan.

  13. Current trends in health insurance systems: OECD countries vs. Japan.

    PubMed

    Sasaki, Toshiyuki; Izawa, Masahiro; Okada, Yoshikazu

    2015-01-01

    Over the past few decades, the longest extension in life expectancy in the world has been observed in Japan. However, the sophistication of medical care and the expansion of the aging society, leads to continuous increase in health-care costs. Medical expenses as a part of gross domestic product (GDP) in Japan are exceeding the current Organization for Economic Co-operation and Development (OECD) average, challenging the universally, equally provided low cost health care existing in the past. A universal health insurance system is becoming a common system currently in developed countries, currently a similar system is being introduced in the United States. Medical care in Japan is under a social insurance system, but the injection of public funds for medical costs becomes very expensive for the Japanese society. In spite of some urgently decided measures to cover the high cost of advanced medical treatment, declining birthrate and aging population and the tendency to reduce hospital and outpatients' visits numbers and shorten hospital stays, medical expenses of Japan continue to be increasing.

  14. Current Trends in Health Insurance Systems: OECD Countries vs. Japan

    PubMed Central

    SASAKI, Toshiyuki; IZAWA, Masahiro; OKADA, Yoshikazu

    2015-01-01

    Over the past few decades, the longest extension in life expectancy in the world has been observed in Japan. However, the sophistication of medical care and the expansion of the aging society, leads to continuous increase in health-care costs. Medical expenses as a part of gross domestic product (GDP) in Japan are exceeding the current Organization for Economic Co-operation and Development (OECD) average, challenging the universally, equally provided low cost health care existing in the past. A universal health insurance system is becoming a common system currently in developed countries, currently a similar system is being introduced in the United States. Medical care in Japan is under a social insurance system, but the injection of public funds for medical costs becomes very expensive for the Japanese society. In spite of some urgently decided measures to cover the high cost of advanced medical treatment, declining birthrate and aging population and the tendency to reduce hospital and outpatients’ visits numbers and shorten hospital stays, medical expenses of Japan continue to be increasing. PMID:25797778

  15. Drug Use before and during Pregnancy in Japan: The Japan Environment and Children's Study.

    PubMed

    Nishigori, Hidekazu; Obara, Taku; Nishigori, Toshie; Metoki, Hirohito; Ishikuro, Mami; Mizuno, Satoshi; Sakurai, Kasumi; Tatsuta, Nozomi; Nishijima, Ichiko; Fujiwara, Ikuma; Arima, Takahiro; Nakai, Kunihiko; Mano, Nariyasu; Kuriyama, Shinichi; Yaegashi, Nobuo

    2017-04-10

    Purpose: To elucidate drug use before and during pregnancy in Japan. Methods: The Japan Environment and Children's Study (JECS) is an ongoing nationwide birth cohort study. We analyzed data from JECS involving cases where drugs were used for 12 months before pregnancy was diagnosed, between the time of diagnosis of pregnancy until week 12 of pregnancy, and after week 12 of pregnancy. Results: We analyzed data from 97,464 pregnant women. The percentages of pregnant women who had taken one or more drugs and supplements before diagnosis of pregnancy, between the time of diagnosis of pregnancy until week 12 of pregnancy, and after week 12 of pregnancy, were 78.4%, 57.1%, and 68.8% respectively. Excluding iron supplements, folic acid, and other vitamins and minerals, the percentages of women taking supplements were 75.3%, 36.0%, and 51.7% at each respective time point. The following drugs and supplements were frequently used for 12 months before pregnancy diagnosis: Commercially available antipyretics, analgesics, and/or medicine for treating common cold (34.7%), antipyretics, analgesics, and/or medicine for treating common colds, which were prescribed in hospitals (29.8%), antimicrobial drugs (14.0%), and anti-allergy drugs (12.5%). The following drugs and supplements were frequently used from the time of pregnancy diagnosis until week 12 of pregnancy, and after week 12 of pregnancy: folic acid (28.9% and 26.2%), antipyretics, analgesics and/or medicines for treating common cold, that were prescribed in hospitals (7.8% and 13.3%), Chinese herbal medicines (6.0% and 9.4%, and uterine relaxants (5.1% and 15.2%). Conclusions: The analysis of a nationwide cohort study showed that a high percentage of Japanese pregnant women were taking medicinal drugs. Further research is required to elucidate the relationship between drug use during pregnancy and birth defects in Japan.

  16. JTEC Panel report on electronic manufacturing and packaging in Japan

    NASA Technical Reports Server (NTRS)

    Kelly, Michael J.; Boulton, William R. (Editor); Kukowski, John; Meieran, Gene; Pecht, Michael; Peeples, John; Tummala, Rao; Dehaemer, Michael J.; Holdridge, Geoff (Editor); Gamota, George

    1995-01-01

    This report summarizes the status of electronic manufacturing and packaging technology in Japan in comparison to that in the United States, and its impact on competition in electronic manufacturing in general. In addition to electronic manufacturing technologies, the report covers technology and manufacturing infrastructure, electronics manufacturing and assembly, quality assurance and reliability in the Japanese electronics industry, and successful product realization strategies. The panel found that Japan leads the United States in almost every electronics packaging technology. Japan clearly has achieved a strategic advantage in electronics production and process technologies. Panel members believe that Japanese competitors could be leading U.S. firms by as much as a decade in some electronics process technologies.

  17. Risk Factor Effects and Total Mortality in Older Japanese Men in Japan and Hawaii

    PubMed Central

    Abbott, Robert D.; Ueshima, Hirotsugu; Hozawa, Atsushi; Okamura, Tomonori; Kadowaki, Takashi; Miura, Katsuyuki; Okuda, Nagako; Nakamura, Yasuyuki; Okayama, Akira; Kita, Yoshikuni; Rodriguez, Beatriz L.; Yano, Katsuhiko; Curb, J. David

    2017-01-01

    Purpose To identify factors related to total mortality in older Japanese men in Japan and Hawaii. Methods Baseline data were collected from 1980 to 1982 in 1,379 men in Hawaii and 954 men in Japan. Ages ranged from 61 to 81 years with mortality follow-up over a 19 year period. Results Compared to Japan, men in Hawaii had a 2-fold excess of diabetes and a 4-fold excess of prevalent coronary heart disease (p<0.001). Total cholesterol and body mass index were also higher in Hawaii (p<0.001). In contrast, men in Japan had higher systolic blood pressure and were nearly 3-times more likely to smoke cigarettes (p<0.001). Although each cohort had elements of a poor risk factor profile, there was a 1.4-fold excess in the risk of death in Japan (49.4 vs. 36.2/1,000 person-years, p<0.001). While mortality was similar after risk factor adjustment, only blood pressure and cigarette smoking accounted for the higher risk of death in Japan. Conclusions Cigarette smoking and hypertension explain much of the excess mortality in Japan versus Hawaii. In this comparison of genetically similar cohorts, evidence further suggests that Japanese in Japan are equally susceptible to develop the same adverse risk factor conditions that exist in Hawaii. PMID:19041590

  18. Recent damaging earthquakes in Japan, 2003-2008

    USGS Publications Warehouse

    Kayen, Robert E

    2008-01-01

    During the last six years, from 2003-2008, Japan has been struck by three significant and damaging earthquakes: The most recent M6.6 Niigata Chuetsu Oki earthquake of July 16, 2007 off the coast of Kashiwazaki City, Japan; The M6.6 Niigata Chuetsu earthquake of October 23, 2004, located in Niigata Prefecture in the central Uonuma Hills; and the M8.0 Tokachi Oki Earthquake of September 26, 2003 effecting southeastern Hokkaido Prefecture. These earthquakes stand out among many in a very active period of seismicity in Japan. Within the upper 100 km of the crust during this period, Japan experienced 472 earthquakes of magnitude 6, or greater. Both Niigata events affected the south-central region of Tohoku Japan, and the Tokachi-Oki earthquake affected a broad region of the continental shelf and slope southeast of the Island of Hokkaido. This report is synthesized from the work of scores of Japanese and US researchers who led and participated in post-earthquake reconnaissance of these earthquakes: their noteworthy and valuable contributions are listed in an extended acknowledgements section at the end of the paper. During the Niigata Chuetsu Oki event of 2007, damage to the Kashiwazaki-Kariwa nuclear power plant, structures, infrastructure, and ground were primarily the product of two factors: (1) high intensity motions from this moderate-sized shallow event, and (2) soft, poor performing, or liquefiable soils in the coastal region of southwestern Niigata Prefecture. Structural and geotechnical damage along the slopes of dunes was ubiquitous in the Kashiwazaki-Kariwa region. The 2004 Niigata Chuetsu Earthquake was the most significant to affect Japan since the 1995 Kobe earthquake. Forty people were killed, almost 3,000 were injured, and many hundreds of landslides destroyed entire upland villages. Landslides were of all types; some dammed streams, temporarily creating lakes threatening to overtop their new embankments and cause flash floods and mudslides. The numerous

  19. Symmetric co-movement between Malaysia and Japan stock markets

    NASA Astrophysics Data System (ADS)

    Razak, Ruzanna Ab; Ismail, Noriszura

    2017-04-01

    The copula approach is a flexible tool known to capture linear, nonlinear, symmetric and asymmetric dependence between two or more random variables. It is often used as a co-movement measure between stock market returns. The information obtained from copulas such as the level of association of financial market during normal and bullish and bearish markets phases are useful for investment strategies and risk management. However, the study of co-movement between Malaysia and Japan markets are limited, especially using copulas. Hence, we aim to investigate the dependence structure between Malaysia and Japan capital markets for the period spanning from 2000 to 2012. In this study, we showed that the bivariate normal distribution is not suitable as the bivariate distribution or to present the dependence between Malaysia and Japan markets. Instead, Gaussian or normal copula was found a good fit to represent the dependence. From our findings, it can be concluded that simple distribution fitting such as bivariate normal distribution does not suit financial time series data, whose characteristics are often leptokurtic. The nature of the data is treated by ARMA-GARCH with heavy tail distributions and these can be associated with copula functions. Regarding the dependence structure between Malaysia and Japan markets, the findings suggest that both markets co-move concurrently during normal periods.

  20. International models of investigator-initiated trials: implications for Japan

    PubMed Central

    Trimble, E. L.; Ledermann, J.; Law, K.; Miyata, T.; Imamura, C. K.; Nam, B.-H.; Kim, Y.H.; Bang, Y.-J.; Michaels, M.; Ardron, D.; Amano, S.; Ando, Y.; Tominaga, T.; Kurokawa, K.; Takebe, N.

    2012-01-01

    Background Academic/institutional investigator-initiated clinical trials benefit individuals and society by supplementing gaps in industry-sponsored clinical trials. Materials In May 2010, experts from Japan, the Republic of Korea, the UK, and the United States, met at a symposium in Tokyo, Japan, to discuss how policies related to the conduct of clinical trials, which have been shown to be effective, may be applied to other regions of the world. Results In order to increase the availability of anticancer drugs world-wide, nations including Japan should examine the benefits of increasing the number of investigator-initiated clinical trials. These trials represent one of the most effective ways to translate basic scientific knowledge into clinical practice. These trials should be conducted under GCP guidelines and include Investigational New Drug application submissions with the ultimate goal of future drug approval. Conclusions To maximize the effectiveness of these trials, a policy to educate health care professionals, cancer patients and their families, and the public in general on the benefits of clinical trials should be strengthened. Finally, policies that expedite the clinical development of novel cancer drugs which have already been shown to be effective in other countries are needed in many nations including Japan to accelerate drug approval. PMID:22843420

  1. [Community-based prevention of drug abuse in Japan].

    PubMed

    Shimane, Takuya

    2010-08-01

    The objective of this article is to review community-based drug abuse prevention and relapse prevention in Japan. Japan has a highly efficient system for the primary prevention of drug abuse; this system includes drug abuse education programs in schools and anti-drug abuse campaigns in communities. On the other hand, relapse prevention activities, such as counseling service at mental health welfare centers, self-help groups for drug addicts, and relapse prevention programs at outpatient clinics, are limited because of zero tolerance policies. Therefore, more relapse prevention activities are required in Japanese communities.

  2. [Nurses' support in smoking cessation therapy in Japan].

    PubMed

    Taniguchi, Chie

    2013-03-01

    Smoking cessation therapy (SCT) was introduced in 2006 in Japan. The patients who wish to stop smoking and receive SCT routinely undergo counseling and advice provided by trained nurse. This paper introduces rationale, methods and contents of the nurses counseling and advice by differentiating physicians' roles in the SCT. We show these supports performed at Nagoya Medical Center, which is one of the famous hospital for the SCT in Japan. Three key issues for the nurses' approach: encouragement of self-decision, promoting self-efficacy and yielding positive thinking are discussed in this paper.

  3. Black brant from Alaska staging and wintering in Japan

    USGS Publications Warehouse

    Derksen, Dirk V.; Bollinger, K.S.; Ward, David H.; Sedinger, J.S.; Miyabayashi, Y.

    1996-01-01

    Black brant (Branta bernicla nigricans) nest in colonies in arctic Canada, Alaska, and Russia (Derksen and Ward 1993, Sedinger et al. 1993). Virtually the entire population stages in fall at Izembek Lagoon near the tip of the Alaska Peninsula (Bellrose 1976) before southward migration (Dau 1992) to winter habitats in British Columbia, Washington, Oregon, California, and Baja California (Subcommittee on Black Brant 1992). A small number of black brant winter in Japan, Korea, and China (Owen 1980). In Japan 3,000–5,000 brant of unknown origin stop over in fall, and a declining population (<1,000) of birds winter here, primarily in the northern islands (Brazil 1991, Miyabayashi et al. 1994). Here, we report sightings of brant in Japan that were marked in Alaska and propose a migration route based on historical and recent observations and weather patterns.

  4. The Politics of Religion: Modernity, Nationhood and Education in Japan

    ERIC Educational Resources Information Center

    Shibata, Masako

    2008-01-01

    While religion in Japan is traditionally linked to nationhood and nation-building, the post-war period has seen Shinto consciously invoked to restore a sense of national identity through a focus on Japan's victimhood. In this context, there is a focus on the Yasukuni Shrine, dedicated to the war dead and an icon of contemporary Japanese cultural…

  5. The genus Microptila Ris (Trichoptera, Hydroptilidae) in Japan.

    PubMed

    Ito, Tomiko

    2017-02-15

    The taxonomy of the genus Microptila Ris in Japan is revised. Microptila orienthula Kjærandsen and Ito, 2009, the only East Palearctic species in the genus, is redescribed with new records and two new species, M. genka sp. nov. and M. nakama sp. nov., are described for adults from Ryukyu Islands, far southern Japan, in the Oriental region.

  6. Japan in the Classroom: Elementary and Secondary Activities, Revised Edition.

    ERIC Educational Resources Information Center

    Parisi, Lynn; And Others

    This activity book is designed to present information and insights on Japanese culture and society. Because few teachers can devote entire units to the study of Japan, the activities focus on teaching about Japan within the context of larger social science units. Some of the lessons can be taught within the context of the humanities and fine arts,…

  7. NanoJapan: international research experience for undergraduates program: fostering U.S.-Japan research collaborations in terahertz science and technology of nanostructures

    NASA Astrophysics Data System (ADS)

    Phillips, Sarah R.; Matherly, Cheryl A.; Kono, Junichiro

    2014-09-01

    The international nature of science and engineering research demands that students have the skillsets necessary to collaborate internationally. However, limited options exist for science and engineering undergraduates who want to pursue research abroad. The NanoJapan International Research Experience for Undergraduates Program is an innovative response to this need. Developed to foster research and international engagement among young undergraduate students, it is funded by a National Science Foundation Partnerships for International Research and Education (PIRE) grant. Each summer, NanoJapan sends 12 U.S. students to Japan to conduct research internships with world leaders in terahertz (THz) spectroscopy, nanophotonics, and ultrafast optics. The students participate in cutting-edge research projects managed within the framework of the U.S-Japan NSF-PIRE collaboration. One of our focus topics is THz science and technology of nanosystems (or `TeraNano'), which investigates the physics and applications of THz dynamics of carriers and phonons in nanostructures and nanomaterials. In this article, we will introduce the program model, with specific emphasis on designing high-quality international student research experiences. We will specifically address the program curriculum that introduces students to THz research, Japanese language, and intercultural communications, in preparation for work in their labs. Ultimately, the program aims to increase the number of U.S. students who choose to pursue graduate study in this field, while cultivating a generation of globally aware engineers and scientists who are prepared for international research collaboration.

  8. Trend of Malpractice Litigation against Neurosurgeons in Japan: An Analysis of Disclosed Database by Courts in Japan from 2001 through 2015.

    PubMed

    Nagashima, Hisashi; Wada, Yoshitaka; Hongo, Kazuhiro

    2017-08-15

    Following the modern raising of public awareness, the numbers of malpractice litigation are increasing in the health care delivery system in Japan despite the extensive efforts of physicians. Authors reviewed the issues of litigation and the reasons for court decision from the healthcare-related negligence lawsuits in the past 15 years in Japan and investigated the cautionary points for reducing potential litigation. Healthcare-related negligence lawsuits between January 2001 and December 2015 were retrieved and sorted in each clinical field from the database in Courts in Japan and investigated on the proportional factors of the claims and court decisions in the neurosurgical field. During the period, 446 of healthcare-related court decisions including 41 against neurosurgeons (9.2%) were retrieved. Three of 41 decisions retrieved were decisions to retries for lower court decisions. In 38 claims against the neurosurgeons, 26 identified the negligence and 12 dismissed. In 26 decisions in favor of the plaintiffs, identified negligence in diagnosis in 4, clinical judgment in 3, technical skills in 5, clinical management in 7 and process of informed consent in 7. Five out of 18 decisions after 2006 were identified as negligence in an informed consent process, and additional one, who was mainly identified in inadequate technical skills also identified existing an inadequate informed consent process as a fundamental cause of litigation. Neurosurgeons are a higher risk group for malpractice litigation in Japan and adequate informed consent is important to reduce the risk of litigation.

  9. Pharmacological interventions for smoking cessation: an overview and network meta-analysis.

    PubMed

    Cahill, Kate; Stevens, Sarah; Perera, Rafael; Lancaster, Tim

    2013-05-31

    Smoking is the leading preventable cause of illness and premature death worldwide. Some medications have been proven to help people to quit, with three licensed for this purpose in Europe and the USA: nicotine replacement therapy (NRT), bupropion, and varenicline. Cytisine (a treatment pharmacologically similar to varenicline) is also licensed for use in Russia and some of the former socialist economy countries. Other therapies, including nortriptyline, have also been tested for effectiveness. How do NRT, bupropion and varenicline compare with placebo and with each other in achieving long-term abstinence (six months or longer)? How do the remaining treatments compare with placebo in achieving long-term abstinence? How do the risks of adverse and serious adverse events (SAEs) compare between the treatments, and are there instances where the harms may outweigh the benefits? The overview is restricted to Cochrane reviews, all of which include randomised trials. Participants are usually adult smokers, but we exclude reviews of smoking cessation for pregnant women and in particular disease groups or specific settings. We cover nicotine replacement therapy (NRT), antidepressants (bupropion and nortriptyline), nicotine receptor partial agonists (varenicline and cytisine), anxiolytics, selective type 1 cannabinoid receptor antagonists (rimonabant), clonidine, lobeline, dianicline, mecamylamine, Nicobrevin, opioid antagonists, nicotine vaccines, and silver acetate. Our outcome for benefit is continuous or prolonged abstinence at least six months from the start of treatment. Our outcome for harms is the incidence of serious adverse events associated with each of the treatments. We searched the Cochrane Database of Systematic Reviews (CDSR) in The Cochrane Library, for any reviews with 'smoking' in the title, abstract or keyword fields. The last search was conducted in November 2012. We assessed methodological quality using a revised version of the AMSTAR scale. For NRT

  10. Japan Studies Association Journal, 2001.

    ERIC Educational Resources Information Center

    Reichel, Philip L., Ed.

    2001-01-01

    This journal presents new perspectives and materials on Japan that are engaging, relatively jargon-free, and shaped so that their usefulness in a college classroom is readily apparent. The journal represents an example of the potential for genuine scholarship that lies within interdisciplinary studies. Articles grouped under the topic of…

  11. Another typhoid patient from Japan.

    PubMed

    Thapa, Rachana; Banskota, Nalin; Pokharel, Jhapindra; Subedi, Bishnu H; Basnyat, Buddha

    2010-01-01

    Typhoid treatment was empirically started in a Japanese patient with undifferentiated fever in Nepal since Japanese tourists, unlike most Americans and Europeans to South Asia, are unable to obtain typhoid vaccination in Japan even for travel to this area of high endemicity. Subsequently, his blood culture grew out Salmonella typhi.

  12. Self-regulation of recombinant DNA technology in Japan in the 1970s.

    PubMed

    Nagai, Hiroyuki; Nukaga, Yoshio; Saeki, Koji; Akabayashi, Akira

    2009-07-01

    Recombinant DNA technology was developed in the United States in the early 1970s. Leading scientists held an international Asilomar Conference in 1975 to examine the self regulation of recombinant DNA technology, followed by the U.S. National Institutes of Health drafting the Recombinant DNA Research Guidelines in 1976. The result of this conference significantly affected many nations, including Japan. However, there have been few historical studies on the self-regulation of recombinant technologies conducted by scientists and government officials in Japan. The purpose of this paper is to analyze how the Science Council of Japan, the Ministry of Education, Science adn Culture, and the Science and Technology Agency developed self-regulation policies for recombinant DNA technology in Japan in the 1970s. Groups of molecular biologist and geneticists played a key role in establishing guidelines in cooperation with government officials. Our findings suggest that self-regulation policies on recombinant DNA technology have influenced safety management for the life sciences and establishment of institutions for review in Japan.

  13. 77 FR 32998 - Tin- and Chromium-Coated Steel Sheet From Japan

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-04

    ... INTERNATIONAL TRADE COMMISSION [Investigation No. 731-TA-860 (Second Review)] Tin- and Chromium... order on tin- and chromium-coated steel sheet from Japan would be likely to lead to continuation or... USITC Publication 4325 (May 2012), entitled Tin- and Chromium-Coated Steel Sheet from Japan...

  14. Neuroreflexotherapy for non-specific low-back pain.

    PubMed

    Urrútia, G; Burton, A K; Morral, A; Bonfill, X; Zanoli, G

    2004-01-01

    Among the wide range of therapeutic alternatives proposed for the management of low-back pain (LBP), a less widely used technique from Spain, called neuroreflexotherapy (NRT) has claimed to show very favourable results, mainly in patients with chronic low-back pain. The aim of this review was to systematically assess the effectiveness of NRT for the treatment of non-specific LBP in adult patients, aged 16 to 65 years. A secondary objective was to compare NRT with other conventional interventions. We searched the Cochrane Central Register of Controlled Trials, MEDLINE, and EMBASE to October 1, 2002. Only randomised controlled trials (RCTs) of NRT for the treatment of patients with a clinical diagnosis of non-specific LBP were included. Two reviewers independently selected trials and extracted data using pre-designed forms. Because the outcome variables were not assessed in a homogenous way, it was not possible to pool the results to obtain an estimate of global effect, as initially planned. Three RCT were included, with a total of 125 subjects randomised to the control groups and 148 subjects receiving active NRT. Neuroreflexotherapy was the same in all three trials, while the control groups received sham-NRT in two trials and standard care in one. Two trials studied patients with chronic LBP, the third studied patients with a mix of chronic and sub-acute LBP. Clinical outcomes were measured in the short-term (15 to 60 days) in all three trials; in one trial, resource utilization was measured after one year. Individuals who received active NRT showed statistically significantly better outcomes than the control groups for measures of pain, degree of mobility, disability, medication use, consumption of resources and costs. No significant differences were observed for quality of life measures. Side effects were more frequently reported in the control groups during short-term follow-up, with no major side effects reported by those receiving active NRT. NRT appears to be

  15. Randomised trial of two nicotine patch protocols distributed through a state quitline.

    PubMed

    Burns, Emily K; Hood, Nancy E; Goforth, Emma; Levinson, Arnold H

    2016-03-01

    Most telephone quitlines provide free nicotine replacement therapy (NRT). An 8-week course is recommended, but few users complete it. Information is needed to help quitlines distribute NRT cost-effectively. Randomised two-group trial. Colorado QuitLine callers who smoked 16-20 cigarettes per day at enrolment and who were eligible for and agreed to receive free NRT. Provision of 4-week versus 8-week NRT supply; the 8-week supply was shipped in halves and required participants to request the second half (split-shipment protocol). Enrolment occurred during March 2010-February 2011, follow-up concluded in November 2011, and analysis was performed in 2012. Point abstinence (7 and 30 day) and prolonged abstinence (6 month) from tobacco use. Overall, 1495 study participants were enrolled and 57.7% completed follow-up. Abstinence rates did not differ significantly between study conditions: 13.8% versus 12.4% in 4-week versus 8-week arms, respectively, (30-day point abstinence, non-respondents treated as smokers). NRT duration was similar in both groups, due in part to purchase of additional patches in the 4-week group. About one-third of the 8-week group requested the full 8-week supply and had higher abstinence rates. Cost per quit was lower in the 4-week (compared to 8-week) group. A randomised trial did not find worse cessation outcomes among quitline users who received half the minimum recommended course of NRT, but offering the full recommended course using a split-shipment protocol may be reasonably cost-effective and supportive of NRT adherers. NCT01889771. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  16. Iron overload patients with unknown etiology from national survey in Japan.

    PubMed

    Ikuta, Katsuya; Hatayama, Mayumi; Addo, Lynda; Toki, Yasumichi; Sasaki, Katsunori; Tatsumi, Yasuaki; Hattori, Ai; Kato, Ayako; Kato, Koichi; Hayashi, Hisao; Suzuki, Takahiro; Kobune, Masayoshi; Tsutsui, Miyuki; Gotoh, Akihiko; Aota, Yasuo; Matsuura, Motoo; Hamada, Yuzuru; Tokuda, Takahiro; Komatsu, Norio; Kohgo, Yutaka

    2017-03-01

    Transfusion is believed to be the main cause of iron overload in Japan. A nationwide survey on post-transfusional iron overload subsequently led to the establishment of guidelines for iron chelation therapy in this country. To date, however, detailed clinical information on the entire iron overload population in Japan has not been fully investigated. In the present study, we obtained and studied detailed clinical information on the iron overload patient population in Japan. Of 1109 iron overload cases, 93.1% were considered to have occurred post-transfusion. There were, however, 76 cases of iron overload of unknown origin, which suggest that many clinicians in Japan may encounter some difficulty in correctly diagnosing and treating iron overload. Further clinical data were obtained for 32 cases of iron overload of unknown origin; median of serum ferritin was 1860.5 ng/mL. As occurs in post-transfusional iron overload, liver dysfunction was found to be as high as 95.7% when serum ferritin levels exceeded 1000 ng/mL in these patients. Gene mutation analysis of the iron metabolism-related genes in 27 cases of iron overload with unknown etiology revealed mutations in the gene coding hemojuvelin, transferrin receptor 2, and ferroportin; this indicates that although rare, hereditary hemochromatosis does occur in Japan.

  17. Profile of tuberculosis among the foreign-born population in Japan, 2007-2014.

    PubMed

    Kawatsu, Lisa; Uchimura, Kazuhiro; Izumi, Kiyohiko; Ohkado, Akihiro; Ishikawa, Nobukatsu

    2016-01-01

    The proportion of foreign-born people among the newly notified tuberculosis (TB) patients has been increasing in recent years and potentially poses a new challenge to TB control in Japan. In this report, we analysed the data from the Japan TB surveillance system between 2007 and 2014 to gain an overview of the trends and characteristics of foreign-born TB patients in Japan. We found that the proportion of foreign-born TB patients was especially high among the younger age groups - 44.1% among the 20-29 years age group in 2014. The largest groups of foreign-born patients were from China and the Philippines; however, the number of those from Nepal and Viet Nam was on the rise. Students comprised the second largest professional category group for TB after regular workers, and its proportion increased over the study period. Compared to Japan-born TB patients, foreign-born patients were more likely to be diagnosed through routine medical check-ups. Treatment successes and patients still on treatment were significantly lower among foreign-born patients than their Japan-born counterparts; and transferred-out and unknown outcomes were higher. Our results indicated that distinctive subgroups within the foreign-born population in Japan, especially students and regular workers, might have a higher risk of developing TB. Measures to ensure early diagnosis and treatment adherence should be adapted to such populations.

  18. Mind your "smoking manners": the tobacco industry tactics to normalize smoking in Japan.

    PubMed

    Kashiwabara, Mina; Armada, Francisco

    2013-11-09

    The tobacco industry has adapted its promotional strategies as tobacco-control measures have increased. This paper describes the tobacco industry's strategies on smoking manners and illustrates how these interfere with tobacco-control policy in Japan where tobacco control remains weak. Information on the tobacco industry's promotional strategies in Japan was collected through direct observation, a review of tobacco industry documents and a literature review. The limitation of the study would be a lack of industry documents from Japan as we relied on a database of a U.S. institution to collect internal documents from the tobacco industry. Japan Tobacco began using the manners strategies in the early 1960s. Collaborating with wide range of actors -including local governments and companies- the tobacco industry has promoted smoking manners to wider audiences through its advertising and corporate social responsibility activities. The tobacco industry in Japan has taken advantage of the cultural value placed on manners in Japan to increase the social acceptability of smoking, eventually aiming to diminish public support for smoke-free policies that threatens the industry's business. A stronger enforcement of the WHO Framework Convention on Tobacco Control is critical to counteracting such strategies.

  19. The Arabidopsis NRG2 Protein Mediates Nitrate Signaling and Interacts with and Regulates Key Nitrate Regulators[OPEN

    PubMed Central

    Zhao, Lufei; Zhang, Chengfei; Li, Zehui; Lei, Zhao; Liu, Fei; Guan, Peizhu; Crawford, Nigel M.

    2016-01-01

    We show that NITRATE REGULATORY GENE2 (NRG2), which we identified using forward genetics, mediates nitrate signaling in Arabidopsis thaliana. A mutation in NRG2 disrupted the induction of nitrate-responsive genes after nitrate treatment by an ammonium-independent mechanism. The nitrate content in roots was lower in the mutants than in the wild type, which may have resulted from reduced expression of NRT1.1 (also called NPF6.3, encoding a nitrate transporter/receptor) and upregulation of NRT1.8 (also called NPF7.2, encoding a xylem nitrate transporter). Genetic and molecular data suggest that NRG2 functions upstream of NRT1.1 in nitrate signaling. Furthermore, NRG2 directly interacts with the nitrate regulator NLP7 in the nucleus, but nuclear retention of NLP7 in response to nitrate is not dependent on NRG2. Transcriptomic analysis revealed that genes involved in four nitrogen-related clusters including nitrate transport and response to nitrate were differentially expressed in the nrg2 mutants. A nitrogen compound transport cluster containing some members of the NRT/PTR family was regulated by both NRG2 and NRT1.1, while no nitrogen-related clusters showed regulation by both NRG2 and NLP7. Thus, NRG2 plays a key role in nitrate regulation in part through modulating NRT1.1 expression and may function with NLP7 via their physical interaction. PMID:26744214

  20. First Zenith Total Delay and Integrated Water Vapour Estimates from the Near Real-Time GNSS Data Processing Systems at the University of Luxembourg

    NASA Astrophysics Data System (ADS)

    Ahmed, F.; Teferle, F. N.; Bingley, R. M.

    2012-04-01

    Since September 2011 the University of Luxembourg in collaboration with the University of Nottingham has been setting up two near real-time processing systems for ground-based GNSS data for the provision of zenith total delay (ZTD) and integrated water vapour (IWV) estimates. Both systems are based on Bernese v5.0, use the double-differenced network processing strategy and operate with a 1-hour (NRT1h) and 15-minutes (NRT15m) update cycle. Furthermore, the systems follow the approach of the E-GVAP METO and IES2 systems in that the normal equations for the latest data are combined with those from the previous four updates during the estimation of the ZTDs. NRT1h currently takes the hourly data from over 130 GNSS stations in Europe whereas NRT15m is primarily using the real-time streams of EUREF-IP. Both networks include additional GNSS stations in Luxembourg, Belgium and France. The a priori station coordinates for all of these stem from a moving average computed over the last 20 to 50 days and are based on the precise point positioning processing strategy. In this study we present the first ZTD and IWV estimates obtained from the NRT1h and NRT15m systems in development at the University of Luxembourg. In a preliminary evaluation we compare their performance to the IES2 system at the University of Nottingham and find the IWV estimates to agree at the sub-millimetre level.

  1. Treating Smokers in Substance Treatment With Contingent Vouchers, Nicotine Replacement and Brief Advice Adapted for Sobriety Settings.

    PubMed

    Rohsenow, Damaris J; Martin, Rosemarie A; Tidey, Jennifer W; Colby, Suzanne M; Monti, Peter M

    2017-01-01

    Treatment for substance use disorders (SUD) provides an opportunity to use voucher-based treatment for smoking. Nicotine replacement (NRT) could improve outcomes previously observed with vouchers without NRT. A randomized controlled trial compared contingent vouchers (CV) for smoking abstinence to noncontingent vouchers (NV), when all received counseling and NRT. Smokers who had not sought smoking treatment (n=340) in residential SUD treatment were provided 14days of vouchers for complete smoking abstinence per exhaled carbon monoxide (CO) after a 5-day smoking reduction period, or vouchers only for breath samples, plus brief advice (four sessions) and 8weeks of NRT. Within treatment, 20% had complete abstinence with CV, 5% with NV (p<.001), and participants showed 50% of days abstinent in CV compared to 22% in NV (p<.001). Across 1, 3, 6 and 12months after randomization, CV resulted in significantly fewer cigarettes per day (p<.01) and fewer days smoking (p<.01), but with small effects. Point-prevalence abstinence differences across follow-up (e.g., 4% CV, 2% in NV at 6 and 12months) were not significant. No differences in substance use were seen. Within-treatment effects on abstinence are stronger than in a prior study of the same CV with BA but without NRT, but NRT does not improve abstinence after vouchers end. Implications for voucher-based treatment include investigating effects when combined with stronger smoking medications and using motivational interviewing. Smoking treatment does not harm SUD recovery. Published by Elsevier Inc.

  2. Preferential expression of an ammonium transporter and of two putative nitrate transporters in root hairs of tomato.

    PubMed Central

    Lauter, F R; Ninnemann, O; Bucher, M; Riesmeier, J W; Frommer, W B

    1996-01-01

    Root hairs as specialized epidermal cells represent part of the outermost interface between a plant and its soil environment. They make up to 70% of the root surface and, therefore, are likely to contribute significantly to nutrient uptake. To study uptake systems for mineral nitrogen, three genes homologous to Arabidopsis nitrate and ammonium transporters (AtNrt1 and AtAmt1) were isolated from a root hair-specific tomato cDNA library. Accumulation of LeNrt1-1, LeNrt1-2, and LeAmt1 transcripts was root-specific, with no detectable transcripts in stems or leaves. Expression was root cell type-specific and regulated by nitrogen availability. LeNrt1-2 mRNA accumulation was restricted to root hairs that had been exposed to nitrate. In contrast, LeNrt1-1 transcripts were detected in root hairs as well as other root tissues under all nitrogen treatments applied. Analogous to LeNrt1-1, the gene LeAmt1 was expressed under all nitrogen conditions tested, and root hair-specific mRNA accumulation was highest following exposure to ammonium. Expression of LeAMT1 in an ammonium uptake-deficient yeast strain restored growth on low ammonium medium, confirming its involvement in ammonium transport. Root hair specificity and characteristics of substrate regulation suggest an important role of the three genes in uptake of mineral nitrogen. Images Fig. 1 Fig. 2 Fig. 3 Fig. 4 Fig. 5 Fig. 6 Fig. 7 PMID:8755617

  3. Treating Smokers in Substance Treatment with Contingent Vouchers, Nicotine Replacement and Brief Advice Adapted for Sobriety Settings

    PubMed Central

    Rohsenow, Damaris J.; Martin, Rosemarie A.; Tidey, Jennifer W.; Colby, Suzanne M.; Monti, Peter M.

    2016-01-01

    Treatment for substance use disorders (SUD) provides an opportunity to use voucher-based treatment for smoking. Nicotine replacement (NRT) could improve outcomes previously observed with vouchers without NRT. Methods A randomized controlled trial compared Contingent Vouchers (CV) for smoking abstinence to Noncontingent Vouchers (NV), when all received counseling and NRT. Smokers who had not sought smoking treatment (n = 340) in residential SUD treatment were provided 14 days of vouchers for complete smoking abstinence per exhaled carbon monoxide (CO) after a 5-day smoking reduction period, or vouchers only for breath samples, plus Brief Advice (four sessions) and 8 weeks of NRT. Results Within treatment, 20% had complete abstinence with CV, 5% with NV (p < .001), and participants showed 50% of days abstinent in CV compared to 22% in NV (p < .001). Across 1, 3, 6 and 12 months after randomization, CV resulted in significantly fewer cigarettes per day (p < .01) and fewer days smoking (p < .01), but with small effects. Point-prevalence abstinence differences across follow-up (e.g., 4% CV, 2% in NV at 6 and 12 months) were not significant. No differences in substance use were seen. Conclusions Within-treatment effects on abstinence are stronger than in a prior study of the same CV with BA but without NRT, but NRT does not improve abstinence after vouchers end. Implications for voucher-based treatment include investigating effects when combined with stronger smoking medications and using motivational interviewing. Smoking treatment does not harm SUD recovery. PMID:27658756

  4. 75 FR 32503 - Stainless Steel Wire Rod From Italy, Japan, Korea, Spain, and Taiwan

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-08

    ...)] Stainless Steel Wire Rod From Italy, Japan, Korea, Spain, and Taiwan Determinations On the basis of the... revocation of the antidumping duty orders on stainless steel wire rod from Italy, Japan, Korea, Spain, and... USITC Publication 4154 (May 2010), entitled Stainless Steel Wire Rod from Italy, Japan, Korea, Spain...

  5. 78 FR 55293 - Chlorinated Isocyanurates From China and Japan; Institution of Antidumping and Countervailing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-10

    ...)] Chlorinated Isocyanurates From China and Japan; Institution of Antidumping and Countervailing Duty... isocyanurates from China and Japan, provided for in subheadings 2933.69.60 and 3808.99.95 of the Harmonized... value by Japan and alleged to be subsidized by China. Unless the Department of Commerce extends the time...

  6. 77 FR 30260 - Welded Large Diameter Line Pipe From Japan: Notice of Rescission of Antidumping Duty...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-22

    ... Administration [A-588-857] Welded Large Diameter Line Pipe From Japan: Notice of Rescission of Antidumping Duty... Japan. The review covers five producers/exporters of welded large diameter line pipe from Japan, which... diameter line pipe from Japan for the period December 1, 2010, through November 30, 2011. See Antidumping...

  7. Children of the new reproductive technologies: social and genetic parenthood.

    PubMed

    Bos, Henny; van Balen, Frank

    2010-12-01

    To review empirical studies on families created by new reproductive technologies (NRT) in which only one parent has a genetic link to the child. Literature search was conducted among computerized databases. Inclusion criteria were that studies should focus on childrearing or parenting, as well as on the psychological adjustment of children in: heterosexual families formed through artificial insemination with donated semen (AID), single-mother AID families, oocyte-donation families, planned lesbian-mother families, planned gay-father families, and partial surrogacy families. Compared to natural-conception parents, parents in these NRT families have better relationships with their children, and their children are functioning well. Although several studies show that parents in NRT families are more emotionally involved in their parenting than are parents in naturally conceived families, no empirical evidence was found that the psychological adjustment of children in NRT families differs from that of their counterparts in natural-conception families. PRACTICAL IMPLICATION: The results inform counselors and infertile couples that concerns regarding the use of NRT in relation to negative consequences for the parent-child relationship or the psychological adjustment of the child are till now unfounded. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

  8. Surrogacy: donor conception regulation in Japan.

    PubMed

    Semba, Yukari; Chang, Chiungfang; Hong, Hyunsoo; Kamisato, Ayako; Kokado, Minori; Muto, Kaori

    2010-09-01

    As of 2008, surrogacy is legal and openly practised in various places; Japan, however, has no regulations or laws regarding surrogacy. This paper reports the situation of surrogacy in Japan and in five other regions (the USA, the UK, Taiwan, Korea and France) to clarify the pros and cons of prohibiting surrogacy, along with the problems and issues relating to surrogacy compensation. Not only in a country such as France that completely prohibits surrogacy within the country, but also in a country such as the UK that allows non-commercial surrogacy, infertile couples travel overseas for the purpose of surrogacy. In addition, some couples might seek underground surrogacy if the government prohibits surrogacy. If an intended parent couple and a surrogate make an agreement among themselves and then a problem occurs, they cannot ask for support from professionals or bring a case to court, as can be observed in South Korea and Taiwan. We also conclude that there is little difference between commercial surrogacy and non-commercial surrogacy in the absence of a clear definition of 'reasonable expenses.' In the UK, the law does not allow surrogates to receive compensation. However, in reality, there may be little difference between the amounts paid to surrogates for profit in the US and those paid to surrogates for reasonable expenses in the UK. We conclude that the issue of surrogacy demands further discussion in Japan.

  9. Websites in Japan: A Qualitative Analysis

    PubMed

    Okuhara, Tsuyoshi; Ishikawa, Hirono; Okada, Masahumi; Kato, Mio; Kiuchi, Takahiro

    2018-02-26

    Background: Cancer screening rates are lower in Japan than in Western countries. Meanwhile, anti-cancer-screening activists take to the internet to spread their messages that cancer screening has little or no efficacy, poses substantial health risks such as side effects from radiation exposure, and that people should forgo cancer screening. We applied a qualitative approach to explore the beliefs underlying the messages of anti-cancer-screening websites, by focusing on perceived value the beliefs provided to those who held them. Methods: We conducted online searches using Google Japan and Yahoo! Japan, targeting websites we classified as “pro,” “anti,” or “neutral” depending on their claims. We applied a dual analytic approach- inductive thematic analysis and deductive interpretative analysis- to the textual data of the anti websites. Results: Of the 88 websites analyzed, five themes that correspond to beliefs were identified: destruction of common knowledge, denial of standard cancer control, education about right cancer control, education about hidden truths, and sense of superiority that only I know the truth. Authors of anti websites ascribed two values (“safety of people” and “self-esteem”) to their beliefs. Conclusion: The beliefs of authors of anti-cancer-screening websites were supposed to be strong. It would be better to target in cancer screening promotion not outright screening refusers but screening hesitant people who are more amenable to changing their attitudes toward screening. The possible means to persuade them were discussed. Creative Commons Attribution License

  10. Enhancements to NASA's Land Atmosphere Near Real-Time Capability for EOS (LANCE)

    NASA Technical Reports Server (NTRS)

    Davies, Diane; Michael, Karen; Schmaltz, Jeffrey; Boller, Ryan A.; Masuoka, Ed; Ye, Gang; Roman, Miguel; Vermote, Eric; Harrison, Sherry; Rinsland, Pamela; hide

    2016-01-01

    NASA's Land, Atmosphere Near real-time Capability for EOS (LANCE) supports application users interested in monitoring a wide variety of natural and man-made phenomena. Near Real- Time (NRT) data and imagery from the AIRS, AMSR2, MISR, MLS, MODIS, OMPS, OMI and VIIRS instruments are available much quicker than routine processing allows. Most data products are available within 3 hours from satellite observation. NRT imagery are generally available 3-5 hours after observation. This article describes the LANCE and the enhancements made to the LANCE over the last year. These enhancements include the addition of NRT products from AMSR2, MISR, OMPS and VIIRS. In addition, the selection of LANCE NRT imagery that can be interactively viewed through Worldview and the Global Imagery Browse Services (GIBS) has been expanded. Next year, data from the MOPITT will be added to the LANCE.

  11. Study and application of molluscicides in Japan*

    PubMed Central

    Komiya, Yoshitaka

    1961-01-01

    For several years after the First World War calcium oxide was the main compound used in the control of Oncomelania nosophora in Japan. This was generally replaced in 1944 by calcium cyanamide; since 1952 the prefectural authorities in areas of endemic bilharziasis have increasingly turned to the use of sodium pentachlorophenate as the molluscicide of choice. Applied at a rate of 5 g per m2, this compound has been found to kill 70%-80% of snails per application. Laboratory and field experiments with calcium-arsenic compounds have been conducted in Japan and have indicated that these products have a relatively high molluscicidal effect; they have, however, not been used on a wide scale for snail control. PMID:14458130

  12. [A nationwide survey for implementation of Health Japan 21 anti-smoking countermeasures in municipalities throughout Japan].

    PubMed

    Shinmura, Hiromi; Wakabayashi, Chihiro; Kunisawa, Naoko; Kayaba, Kazunori; Miura, Yoshihiko; Ojima, Toshiyuki; Yanagawa, Hiroshi

    2008-03-01

    Smoking cessation is one of the most important items for improvement of health in Japan. The Japanese government started a new campaign called the "Health Japan 21" to promote better health of Japanese citizens in the 21st century. The purpose of the present study was to observe the situation of the municipalities throughout Japan regarding implementation of anti-smoking countermeasures and setting of the level of target values to be achieved over the next ten years. Mail questionnaire forms were sent to 953 municipalities which had formulated specific local plans for the promotion of health. Of this total, 793 (83.2%) responded to the inquiry. The most commonly implemented countermeasure against smoking was restricting smoking only to limited areas in municipality offices (75%), followed by providing support for stopping smoking (35%), and providing a complete smoke free environment in municipality offices (32.4%). Proportions of local governments putting a ban on smoking on public roads (7.5%), giving publicity to restaurants with smoking restrictions (< 5%) and setting no smoking times in the municipality offices (< 5%) were low. Some 70% of municipalities provided anti-smoking education for school children. Very few local governments took measures such as identifying age at purchasing tobacco, removing vending machines and restricting tobacco advertisement. Most municipalities have made much of anti-smoking activities. However, measures for school children were not satisfactorily implemented. The execution rates for anti-smoking activities are low in small-scale municipalities and therefore it is necessary to provide particular support in these cases.

  13. Viewpoint of Science Council of Japan

    NASA Astrophysics Data System (ADS)

    Ikeda, Syunsuke

    The Science Council of Japan (SCJ) is an academic body that represents Japanese 700,000 scientists. The activity of SCJ is changing rapidly, in which the science associated with society is increasingly important. In this context, the engineering education for ethics is treated at SCJ. The importance of engineering ethics was first recognized at the 5th division of 17th term (1999-2001) of SCJ, in which education for engineering ethics based on the analysis of ethical problems occurred in Japan is recommended and it asked the engineering societies to establish the code of ethics. Following this proposal, SCJ founded a committee to treat the problem at 18th and 19th terms. The committee proposed a procedure to prevent misconduct associated with scientific activities and the importance of education of science and engineering ethics especially for young students at tertiary education.

  14. Mapping seismic azimuthal anisotropy of the Japan subduction zone

    NASA Astrophysics Data System (ADS)

    Zhao, D.; Liu, X.

    2016-12-01

    We present 3-D images of azimuthal anisotropy tomography of the crust and upper mantle of the Japan subduction zone, which are determined using a large number of high-quality P- and S-wave arrival-time data of local earthquakes and teleseismic events recorded by the dense seismic networks on the Japan Islands. A tomographic method for P-wave velocity azimuthal anisotropy is modified and extended to invert S-wave travel times for 3-D S-wave velocity azimuthal anisotropy. A joint inversion of the P and S wave data is conducted to constrain the 3-D azimuthal anisotropy of the Japan subduction zone. Main findings of this work are summarized as follows. (1) The high-velocity subducting Pacific and Philippine Sea (PHS) slabs exhibit trench-parallel fast-velocity directions (FVDs), which may reflect frozen-in lattice-preferred orientation of aligned anisotropic minerals formed at the mid-ocean ridge as well as shape-preferred orientation such as normal faults produced at the outer-rise area near the trench axis. (2) Significant trench-normal FVDs are revealed in the mantle wedge, which reflects corner flow in the mantle wedge due to the active subduction and dehydration of the oceanic plates. (3) Obvious toroidal FVDs and low-velocity anomalies exist in and around a window (hole) in the aseismic PHS slab beneath Southwest Japan, which may reflect a toroidal mantle flow pattern resulting from hot and wet mantle upwelling caused by the joint effects of deep dehydration of the Pacific slab and the convective circulation process in the mantle wedge above the Pacific slab. (4) Significant low-velocity anomalies with trench-normal FVDs exist in the mantle below the Pacific slab beneath Northeast Japan, which may reflect a subducting oceanic asthenosphere affected by hot mantle upwelling from the deeper mantle. ReferencesLiu, X., D. Zhao (2016) Seismic velocity azimuthal anisotropy of the Japan subduction zone: Constraints from P and S wave traveltimes. J. Geophys. Res. 121, doi

  15. Bordetella pertussis population dynamics and phylogeny in Japan after adoption of acellular pertussis vaccines.

    PubMed

    Zomer, Aldert; Otsuka, Nao; Hiramatsu, Yukihiro; Kamachi, Kazunari; Nishimura, Naoko; Ozaki, Takao; Poolman, Jan; Geurtsen, Jeroen

    2018-05-17

    Bordetella pertussis, the causative agent of whooping cough, has experienced a resurgence in the past 15 years, despite the existence of both whole-cell and acellular vaccines. Here, we performed whole genome sequencing analysis of 149 clinical strains, provided by the National Institute of Infectious Diseases (NIID), Japan, isolated in 1982-2014, after Japan became the first country to adopt acellular vaccines against B. pertussis. Additionally, we sequenced 39 strains provided by the Konan Kosei Hospital in Aichi prefecture, Japan, isolated in 2008-2013. The genome sequences afforded insight into B. pertussis genome variability and population dynamics in Japan, and revealed that the B. pertussis population in Japan was characterized by two major clades that divided more than 40 years ago. The pertactin gene was disrupted in about 20 % of the 149 NIID isolates, by either a deletion within the signal sequence (ΔSS) or the insertion of IS element IS481 (prn :: IS481). Phylogeny suggests that the parent clones for these isolates originated in Japan. Divergence dating traced the first generation of the pertactin-deficient mutants in Japan to around 1990, and indicated that strains containing the alternative pertactin allele prn2 may have appeared in Japan around 1974. Molecular clock data suggested that observed fluctuations in B. pertussis population size may have coincided with changes in vaccine usage in the country. The continuing failure to eradicate the disease warrants an exploration of novel vaccine compositions.

  16. National surveillance of Salmonella Enteritidis in commercial eggs in Japan.

    PubMed

    Esaki, H; Shimura, K; Yamazaki, Y; Eguchi, M; Nakamura, M

    2013-05-01

    A total of 105 033 eggs were collected across Japan from June 2010 to January 2011 and tested for Salmonella Enteritidis to provide data for the risk profiling of S. Enteritidis in eggs by the Food Safety Commission of Japan. S. Enteritidis isolates were recovered from three samples (20 eggs/sample) and these samples were different in regard to sampling period, grading and packaging centre and farm. The prevalence of S. Enteritidis in commercial eggs in Japan is estimated at ~0.003% which was a tenfold decrease in prevalence compared to similar surveillance in the mid 1990s. The decrease in the contamination in commercial eggs is considered a contributory factor in the decrease of foodborne diseases associated with S. Enteritidis in this period.

  17. Current affairs in earthquake prediction in Japan

    NASA Astrophysics Data System (ADS)

    Uyeda, Seiya

    2015-12-01

    As of mid-2014, the main organizations of the earthquake (EQ hereafter) prediction program, including the Seismological Society of Japan (SSJ), the MEXT Headquarters for EQ Research Promotion, hold the official position that they neither can nor want to make any short-term prediction. It is an extraordinary stance of responsible authorities when the nation, after the devastating 2011 M9 Tohoku EQ, most urgently needs whatever information that may exist on forthcoming EQs. Japan's national project for EQ prediction started in 1965, but it has made no success. The main reason for no success is the failure to capture precursors. After the 1995 Kobe disaster, the project decided to give up short-term prediction and this stance has been further fortified by the 2011 M9 Tohoku Mega-quake. This paper tries to explain how this situation came about and suggest that it may in fact be a legitimate one which should have come a long time ago. Actually, substantial positive changes are taking place now. Some promising signs are arising even from cooperation of researchers with private sectors and there is a move to establish an "EQ Prediction Society of Japan". From now on, maintaining the high scientific standards in EQ prediction will be of crucial importance.

  18. Risk factors for aneurysmal subarachnoid hemorrhage in Aomori, Japan.

    PubMed

    Ohkuma, Hiroki; Tabata, Hidefumi; Suzuki, Shigeharu; Islam, Md Shafiqul

    2003-01-01

    Japan is known to have an incidence of aneurysmal subarachnoid hemorrhage (SAH) as high as that in Finland, where SAH is especially common. However, the risk factors for SAH in Japan are unknown. The purpose of this study was to identify the risk factors and then examine their possible roles in cases of SAH in Japan. Case-control data were collected in the Aomori prefecture between June 2000 and May 2001 and in the Shimokita area between 1989 and 1998. A history of hypertension, cigarette smoking, alcohol consumption, hypercholesterolemia, and diabetes mellitus were examined as possible risk factors for SAH by using stepwise logistic regression analysis. Stepwise logistic regression analysis showed that a history of hypertension and current smoking increased the risk of SAH and that a history of hypercholesterolemia decreased the risk of SAH. Alcohol consumption and a history of diabetes mellitus were excluded from the model, because their log-likelihood ratios were not significant. The adjusted odds ratios, obtained by forcing matching factors, were 2.29 for a history of hypertension (95% CI, 1.66 to 3.16), 3.12 for current smoking (95% CI, 2.05 to 4.77), and 0.41 for a history of hypercholesterolemia (95% CI, 0.24 to 0.71). The prevalence of hypertension in control subjects was 27% in men and 31% in women, whereas the prevalence of cigarette smoking in control subjects was 46% in men and 9% in women. Hypertension and cigarette smoking seem to be independent risk factors for SAH in Japan. The high prevalence of hypertension in both sexes and the high prevalence of cigarette smoking in men in the general population might contribute to the high incidence of SAH in Japan.

  19. Can GRACE detect winter snows in Japan?

    NASA Astrophysics Data System (ADS)

    Heki, Kosuke

    2010-05-01

    Current spatial resolution of the GRACE (Gravity Recovery and Climate Experiment) satellites is 300-400 km, and so its hydrological applications have been limited to continents and large islands. The Japanese Islands have width slightly smaller than this spatial resolution, but are known to show large amplitude seasonal changes in surface masses due mainly to winter snow. Such loads are responsible for seasonal crustal deformation observed with GEONET, a dense array of GPS (Global Positioning System) receivers in Japan (Heki, 2001). There is also a dense network of surface meteorological sensors for, e.g. snow depths, atmospheric pressures, etc. Heki (2004) showed that combined effects of surface loads, i.e. snow (predominant), atmosphere, soil moisture, dam impoundment, can explain seasonal crustal deformation observed by GPS to a large extent. The total weight of the winter snow in the Japanese Islands in its peak season may reach ~50 Gt. This is comparable to the annual loss of mountain glaciers in the Asian high mountains (Matsuo & Heki, 2010), and is above the detection level of GRACE. In this study, I use GRACE Level-2 Release-4 data from CSR, Univ. Texas, up to 2009 November, and evaluated seasonal changes in surface loads in and around the Japanese Islands. After applying a 350 km Gaussian filter and a de-striping filter, the peak-to-peak change of the water depth becomes ~4 cm in northern Japan. The maximum value is achieved in February-March. The region of large winter load spans from Hokkaido, Japan, to northeastern Honshu, which roughly coincides with the region of deep snow in Japan. Next I compiled snow depth data from surface meteorological observations, and converted them to loads using time-dependent snow density due to compaction. By applying the same spatial filter as the GRACE data, its spatial pattern becomes similar to the GRACE results. The present study suggests that GRACE is capable of detecting seasonal mass changes in an island arc not

  20. An Application of Convergence Theory to Japan's Post-WWII Economic "Miracle."

    ERIC Educational Resources Information Center

    Valdes, Benigno

    2003-01-01

    Provides an explanation of the post-World War II economic phenomenon of Japan as a process of economic convergence within the framework of the neoclassical Solo-Swan model of economic growth. States that this interpretation helps students understand economic growth and development and Japan's modern economic history. (JEH)

  1. National Response Team

    EPA Pesticide Factsheets

    Response planning and coordination (not direct response itself) is accomplished at the federal level through the U.S. National Response Team (NRT), an interagency group co-chaired by EPA and U.S. Coast Guard. NRT distributes information, plans, and trains.

  2. Direct disposal of spent fuel: developing solutions tailored to Japan

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kawamura, Hideki; McKinley, Ian G

    2013-07-01

    With the past Government policy of 100% reprocessing in Japan now open to discussion, options for direct disposal of spent fuel (SF) are now being considered in Japan. The need to move rapidly ahead in developing spent fuel management concepts is closely related to the ongoing debate on the future of nuclear power in Japan and the desire to understand the true costs of the entire life cycle of different options. Different scenarios for future nuclear power - and associated decisions on extent of reprocessing - will give rise to quite different inventories of SF with different disposal challenges. Althoughmore » much work has been carried out spent fuel disposal within other national programmes, the potential for mining the international knowledge base is limited by the boundary conditions for disposal in Japan. Indeed, with a volunteer approach to siting, no major salt deposits and few undisturbed sediments, high tectonic activity, relatively corrosive groundwater and no deserts, it is evident that a tailored solution is needed. Nevertheless, valuable lessons can be learned from projects carried out worldwide, if focus is placed on basic principles rather than implementation details. (authors)« less

  3. Resources for Teaching about Japan.

    ERIC Educational Resources Information Center

    Wojtan, Linda S.

    This book lists resources for materials and ideas for teaching about Japan. The resource listings are not intended to be encyclopedic and are not intended to be a comprehensive listing of every useful curriculum item. The attempt has been made to highlight especially those organizations that work with kindergarten through grade 12 teachers,…

  4. [Marriage and divorce in Japan].

    PubMed

    Haderka, J

    1986-01-01

    Marriage patterns in Japan are analyzed using data from secondary sources. The author notes that although legislation affecting marriage and the family is derived from European models, traditional Japanese attitudes concerning the subservient role of women have a significant impact. The problems faced by women experiencing divorce are noted. (SUMMARY IN ENG AND RUS)

  5. 78 FR 50378 - Diffusion-Annealed, Nickel-Plated Flat-Rolled Steel Products From Japan: Postponement of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-19

    ...-Plated Flat-Rolled Steel Products From Japan: Postponement of Preliminary Determination of Antidumping... investigation of diffusion-annealed, nickel-plated flat-rolled steel products from Japan. See Diffusion- Annealed, Nickel-Plated Flat-Rolled Steel Products From Japan: Initiation of Antidumping Duty Investigation...

  6. Characteristics of an external employee assistance programme in Japan.

    PubMed

    Muto, Takashi; Fujimori, Yuiko; Suzuki, Keiko

    2004-12-01

    Mental health care is now a major occupational health issue in Japan. Although realizing effective use of external employee assistance programmes (EAPs) has been identified as crucial for mental health care, few scientific papers describe or analyse the characteristics of EAPs in Japan. This study sought to clarify the characteristics of an external EAP in Japan. The characteristics of an external EAP were clarified in terms of programme description and utilization. A total of 10,260 counselling sessions from 1996 to 2000 were used for utilization analysis. The EAP studied had contracts with 133 organizations, half of which were health insurance societies. The EAP provided employees and family members with free, confidential counselling. Annual mean utilization rate per 1000 individuals increased from 1.3 in 1996 to 2.7 in 2000. Less than one-third of counselling sessions were for work-related mental health issues, and male users (30%) consulted significantly more often than female users (14%) for such problems. Among men, career development issues were most common, while job dissatisfaction was highest among women. Absenteeism, depression and fatigue were the most frequently observed problems in both sexes. EAP use in Japan is rising. The majority of its use is for non-work-related health issues. Male users were more likely to consult for work-related mental health problems.

  7. A Review of Recent RLV Research Activities in Japan

    NASA Astrophysics Data System (ADS)

    Sasaki, Makoto; Watanabe, Atsutaro

    2004-02-01

    Researches on reusable launch vehicle (RLV) in Japan have been conducted mainly by the three space agencies: the National Space Development Agency of Japan (NASDA), the National Aerospace Laboratory of Japan (NAL) and the Institute of Space and Astronautical Science (ISAS). HOPE-X program by NASDA/NAL, spaceplane/scramjet related researches by NAL, and development studies of ATREX engine and small reusable vehicle testing (RVT) by ISAS are such major activities. After the consecutive launch failures of NASDA's H-II and ISAS's M-V rockets in 1999-2000, it was concluded that more intensive efforts should be concentrated on the reliability improvement of those major expendable vehicles and that RLV related researches should be promoted to establish fundamental technologies essential to future RLV. In past two years, NASDA succeeded in five consecutive launches of new H-IIA, and ISAS successfully resumed the launch of M-V. As for RLV researches, considerable progress has been achieved in the high speed flight demonstration (HSFD) tests of HOPE-X program, scramjet tests of Mach 4 to 8 by NAL, and ATREX engine and small RVT tests by ISAS. The current three space agencies will be merged into one in October 2003 to establish a new organization named Japan Aerospace Exploration Agency (JAXA). It is expected that the above research activities will be also merged to promote a higher-level research program on RLV.

  8. The Lewisian turning point and international migration: the case of Japan.

    PubMed

    Watanabe, S

    1994-01-01

    "This article critically examines the Lewisian turning point [concerning the availability of unlimited manpower resources] in light of Japan's experience since the mid-1800s. Japan reached its Lewisian turning point around 1960. Contrary to the assumptions of the theory however, the findings for Japan indicate that political factors have been more determinative of the rate of migration than purely economic ones. Prior to its turning point in 1960, international relations, war and forced repatriation were the decisive factors. Recently, though the inflow of foreign workers to fill labor shortages has increased, so also has the outflow of Japanese to accompany direct foreign investment." excerpt

  9. DOE Robotic and Remote Systems Assistance to the Government of Japan

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Derek Wadsworth; Victor Walker

    At the request of the Government of Japan, DOE did a complex wide survey of available remotely operated and robotic systems to assist in the initial assessment of the damage to the Fukushima Daiichi reactors following an earthquake and subsequent tsunami. As a result several radiation hardened cameras and a Talon robot were identified as systems that could immediately assist in the effort and were subsequently sent to Japan. These systems were transferred to the Government of Japan and used to map radiation levels surrounding the damaged facilities. This report describes the equipment, its use, data collected, and lessons learnedmore » from the experience.« less

  10. Analysis of Critical Earth Observation Priorities for Societal Benefit

    NASA Astrophysics Data System (ADS)

    Zell, E. R.; Huff, A. K.; Carpenter, A. T.; Friedl, L.

    2011-12-01

    To ensure that appropriate near real-time (NRT) and historical Earth observation data are available to benefit society and meet end-user needs, the Group on Earth Observations (GEO) sponsored a multi-disciplinary study to identify a set of critical and common Earth observations associated with 9 Societal Benefit Areas (SBAs): Agriculture, Biodiversity, Climate, Disasters, Ecosystems, Energy, Health, Water, and Weather. GEO is an intergovernmental organization working to improve the availability, access, and use of Earth observations to benefit society through a Global Earth Observation System of Systems (GEOSS). The study, overseen by the GEO User Interface Committee, focused on the "demand" side of Earth observation needs: which users need what types of data, and when? The methodology for the study was a meta-analysis of over 1,700 publicly available documents addressing Earth observation user priorities, under the guidance of expert advisors from around the world. The result was a ranking of 146 Earth observation parameters that are critical and common to multiple SBAs, based on an ensemble of 4 statistically robust methods. Within the results, key details emerged on NRT observations needed to serve a broad community of users. The NRT observation priorities include meteorological parameters, vegetation indices, land cover and soil property observations, water body and snow cover properties, and atmospheric composition. The results of the study and examples of NRT applications will be presented. The applications are as diverse as the list of priority parameters. For example, NRT meteorological and soil moisture information can support monitoring and forecasting for more than 25 infectious diseases, including epidemic diseases, such as malaria, and diseases of major concern in the U.S., such as Lyme disease. Quickly evolving events that impact forests, such as fires and insect outbreaks, can be monitored and forecasted with a combination of vegetation indices, fuel

  11. Structured Strategy for Implementation of the Teaching Portfolio Concept in Japan

    ERIC Educational Resources Information Center

    Kurita, Kayoko

    2013-01-01

    This paper describes a strategy for successfully implementing the teaching portfolio in higher education institutions in Japan. The teaching portfolio has gained recognition in Japan in the last few years as an effective instrument for improving and showcasing teaching performance. It is well known that the implementation process is very important…

  12. Moving towards Effective English Language Teaching in Japan: Issues and Challenges

    ERIC Educational Resources Information Center

    Sakamoto, Mitsuyo

    2012-01-01

    Compared with other countries in Asia, Japan is far behind in terms of introducing and delivering bilingual education, let alone effective immersion programmes. In order to make its citizens more bilingual, Japan has been introducing innovative measures including the implementation of the teaching of English in elementary education and a new…

  13. A Survey On Management Of Software Engineering In Japan

    NASA Astrophysics Data System (ADS)

    Kadono, Yasuo; Tsubaki, Hiroe; Tsuruho, Seishiro

    2008-05-01

    The purpose of this study is to clarity the mechanism of how software engineering capabilities relate to the business performance of IT vendors in Japan. To do this, we developed a structural model using factors related to software engineering, business performance and competitive environment. By analyzing the data collected from 78 major IT vendors in Japan, we found that superior deliverables and business performance were correlated with the effort expended particularly on human resource development, quality assurance, research and development and process improvement.

  14. Mt. Fuji, Honshu, Japan

    NASA Image and Video Library

    1981-10-14

    STS002-09-390 (12-14 Nov. 1981) --- Honshu Island, Japan, and its snow-covered Fuji-San or Fuji-Yama volcano are the features of this 70mm frame. The volcano peak is 12,400 feet tall. The western suburbs of Tokyo are at right edge of the photograph. Isu Peninsula is at the bottom, separating the Suruga and Sagami Bay. Other large cities include Yokohama, Kozu, Shizuoka, Namazu and Odawara. Photo credit: NASA

  15. Attitudes toward Education Expenditures in Japan: Comparisons with Social Security and Welfare Services Expenditures

    ERIC Educational Resources Information Center

    Nakazawa, Wataru

    2015-01-01

    This paper examines people's attitudes toward public spending on education in Japan. It is well known that Japan has the smallest public education expenditure relative to GDP among the OECD countries, and this may yield unequal opportunities in education. The tax burden in Japan is small compared to those in OECD countries, and there may be no…

  16. Attributable causes of cancer in Japan in 2005--systematic assessment to estimate current burden of cancer attributable to known preventable risk factors in Japan.

    PubMed

    Inoue, M; Sawada, N; Matsuda, T; Iwasaki, M; Sasazuki, S; Shimazu, T; Shibuya, K; Tsugane, S

    2012-05-01

    To contribute to evidence-based policy decision making for national cancer control, we conducted a systematic assessment to estimate the current burden of cancer attributable to known preventable risk factors in Japan in 2005. We first estimated the population attributable fractions (PAFs) of each cancer attributable to known risk factors from relative risks derived primarily from Japanese pooled analyses and large-scale cohort studies and the prevalence of exposure in the period around 1990. Using nationwide vital statistics records and incidence estimates, we then estimated the attributable cancer incidence and mortality in 2005. In 2005, ≈ 55% of cancer among men was attributable to preventable risk factors in Japan. The corresponding figure was lower among women, but preventable risk factors still accounted for nearly 30% of cancer. In men, tobacco smoking had the highest PAF (30% for incidence and 35% for mortality, respectively) followed by infectious agents (23% and 23%). In women, in contrast, infectious agents had the highest PAF (18% and 19% for incidence and mortality, respectively) followed by tobacco smoking (6% and 8%). In Japan, tobacco smoking and infections are major causes of cancer. Further control of these factors will contribute to substantial reductions in cancer incidence and mortality in Japan.

  17. Bovine mastitis outbreak in Japan caused by methicillin-resistant Staphylococcus aureus New York/Japan clone.

    PubMed

    Hata, Eiji

    2016-05-01

    Many methicillin-resistant Staphylococcus aureus (MRSA) strains are multidrug-resistant; consequently, infectious diseases involving MRSA are recognized as troublesome diseases not only in human health care but also in animal health care. A bovine mastitis case caused by MRSA isolates of the New York/Japan clone (NJC), which occurred in Japan in 2005, was monitored in the current study. Isolates of the NJC are typical of hospital-acquired MRSA in Japan. The genetic backgrounds of these strains differ from those of bovine-associated S. aureus, which are typically of clonal complex (CC)97, CC705, and CC133. Moreover, the NJC isolates in this bovine outbreak possessed a β-hemolysin-converting bacteriophage and an immune evasion cluster, as found in the NJC isolates from humans, so it is possible that this clone was introduced into the dairy herd by a human carrier. Most bovine intramammary infections (IMIs) caused by the NJC isolates in our study were asymptomatic, and obvious clinical signs were recognized in only the first 3 infected cows. Of a total of 78 cows, 31 cows were MRSA carriers, and these carrier cows were detected by testing the milk of all lactating cows at 1-month intervals. These S. aureus carrier cows were culled or the infected quarter was dried off and no longer milked. Both IMI and mastitis caused by MRSA were completely eradicated after 5 months. Genotyping data suggested that exchanging of the staphylococcal cassette chromosome mec (the determining factor in methicillin resistance) occurred easily between MRSA and methicillin-sensitive S. aureus in the udders of carrier cows. This case study demonstrates an effective procedure against the spread of MRSA in a dairy herd, and highlights the risk of emergence of new MRSA strains in a dairy herd. © 2016 The Author(s).

  18. Modernization of Education in Japan.

    ERIC Educational Resources Information Center

    National Inst. for Educational Research, Tokyo (Japan).

    The document traces the development of education in Japan from the 17th century to the present. It is presented in four chapters. Chapter one discusses the Tokugawa Period (1603-1867). Principal forms of schooling were hanko for the Samurai class and terakoya for the commoners. The hanko were established for the benefit of the fiefs; objectives of…

  19. How Japan Supports Novice Teachers

    ERIC Educational Resources Information Center

    Ahn, Ruth

    2014-01-01

    When U.S. educators first hear that Japanese teacher preparation programs require only four weeks of formal student teaching at the end of the credential program, they're appalled: How can this be? More surprising still, few new teachers in Japan (1.35 percent) leave the profession during their first year. So where are these beginning teachers…

  20. Teaching and Learning in Japan.

    ERIC Educational Resources Information Center

    Rohlen, Thomas P., Ed.; LeTendre, Gerald K., Ed.

    The essays gathered in this volume are united by the common goal of understanding teaching and learning in Japan as it actually occurs. The essays seek to answer questions about the actual conduct of learning in different settings and at different points in the life cycle. This volume explores the expectations and associations found in specific…

  1. Use of nicotine replacement therapy to reduce or delay smoking but not to quit: prevalence and association with subsequent cessation efforts.

    PubMed

    Levy, Douglas E; Thorndike, Anne N; Biener, Lois; Rigotti, Nancy A

    2007-12-01

    To assess the prevalence of nicotine replacement therapy (NRT) use for purposes other than quitting smoking and examine the relation of this non-standard NRT use (NSNRT) with subsequent smoking cessation efforts. A population based cohort study of adult smokers who were interviewed by telephone at baseline (2001-2) and at two year follow-up. The association between NSNRT use to cut down on smoking or to delay smoking before baseline and cessation attempts and smoking outcomes at two year follow-up was assessed using logistic regression to adjust for multiple potential confounding factors. Massachusetts, USA. 1712 adult smokers in Massachusetts who were selected using a random digit dial telephone survey. Quit attempt in 12 months before follow-up, NRT use at quit attempt in 12 months before follow-up, smoking cessation by follow-up, or 50% reduction in cigarettes smoked per day between baseline and follow-up. 18.7% of respondents reported ever having used NSNRT. In a multiple logistic regression analysis, there was no statistically significant association between past NSNRT use and quit attempts (OR(cut down) = 0.89, 95% CI 0.59 to 1.33; OR(delay) = 1.29, 95% CI 0.73 to 2.29), smoking cessation (OR(cut down) = 0.74, 95% CI 0.43 to 1.24; OR(delay) = 1.22, 95% CI 0.60 to 2.50) or 50% reduction in cigarettes smoked per day (OR(cut down) = 0.93, 95% CI 0.62 to 1.38; OR(delay) = 0.80, 95% CI 0.43 to 1.49) at follow-up. Past use of NRT to cut down on cigarettes was associated with use of NRT at a follow-up quit attempt (OR(cut down) = 2.28, 95% CI 1.50 to 3.47) but past use of NRT to delay smoking was not (OR(delay) = 1.25, 95% CI 0.67 to 2.34). Use of NRT for reasons other than quitting smoking may be more common than was previously estimated. This population based survey finds no strong evidence that NRT use for purposes other than quitting smoking is either harmful or helpful.

  2. Use of nicotine replacement therapy to reduce or delay smoking but not to quit: prevalence and association with subsequent cessation efforts

    PubMed Central

    Levy, Douglas E; Thorndike, Anne N; Biener, Lois; Rigotti, Nancy A

    2007-01-01

    Objective To assess the prevalence of nicotine replacement therapy (NRT) use for purposes other than quitting smoking and examine the relation of this non‐standard NRT use (NSNRT) with subsequent smoking cessation efforts. Design A population based cohort study of adult smokers who were interviewed by telephone at baseline (2001–2) and at two year follow‐up. The association between NSNRT use to cut down on smoking or to delay smoking before baseline and cessation attempts and smoking outcomes at two year follow‐up was assessed using logistic regression to adjust for multiple potential confounding factors. Setting Massachusetts, USA. Subjects 1712 adult smokers in Massachusetts who were selected using a random digit dial telephone survey. Main outcome measures Quit attempt in 12 months before follow‐up, NRT use at quit attempt in 12 months before follow‐up, smoking cessation by follow‐up, or 50% reduction in cigarettes smoked per day between baseline and follow‐up. Results 18.7% of respondents reported ever having used NSNRT. In a multiple logistic regression analysis, there was no statistically significant association between past NSNRT use and quit attempts (ORcut down  = 0.89, 95% CI 0.59 to 1.33; ORdelay  = 1.29, 95% CI 0.73 to 2.29), smoking cessation (ORcut down  = 0.74, 95% CI 0.43 to 1.24; ORdelay  = 1.22, 95% CI 0.60 to 2.50) or 50% reduction in cigarettes smoked per day (ORcut down  = 0.93, 95% CI 0.62 to 1.38; ORdelay  = 0.80, 95% CI 0.43 to 1.49) at follow‐up. Past use of NRT to cut down on cigarettes was associated with use of NRT at a follow‐up quit attempt (ORcut down  = 2.28, 95% CI 1.50 to 3.47) but past use of NRT to delay smoking was not (ORdelay  = 1.25, 95% CI 0.67 to 2.34). Conclusions Use of NRT for reasons other than quitting smoking may be more common than was previously estimated. This population based survey finds no strong evidence that NRT use for purposes other than quitting

  3. Learning from others. Japan's role in bringing psychology to China.

    PubMed

    Blowers, G

    2000-12-01

    Recent research by Chinese and Japanese historians of psychology and education suggests that it was educational reformers' copying of Japan's education system in the 1st decade of the 20th century that provided the context for developing modern psychology in China. Psychology, although not well understood by those reformers, was thought to be useful in teacher training. In 1902 Japanese psychology teachers came to China and some textbooks were translated. Chinese students studying in Japan also brought back psychological knowledge in translations. However, the Chinese attraction to study in Japan declined after 1906. As the United States opened new universities and provided opportunities for Chinese students to study in U.S. schools, it became a more attractive option for later generations of Chinese, who saw psychology become established as a separate discipline.

  4. Seismicity of the Earth 1900-2007, Japan and Vicinity

    USGS Publications Warehouse

    Rhea, Susan; Tarr, Arthur C.; Hayes, Gavin P.; Villaseñor, Antonio; Benz, Harley

    2010-01-01

    This map shows details of Japan and vicinity not visible in an earlier publication, U.S. Geological Survey Scientific Investigations Map 3064. Japan and its island possessions lie across four major tectonic plates: Pacific plate, North America plate; Eurasia plate; and Philippine Sea plate. The Pacific plate is subducted into the mantle, beneath Hokkaido and northern Honshu, along the eastern margin of the Okhotsk microplate, a proposed subdivision of the North America plate (Bird, 2003). Farther south, the pacific plate is subducted beneath volcanic islands along the eastern margin of the Philippine Sea plate. This 2,200 km-long zone of subduction of the Pacific plate is responsible for the creation of the deep offshore Ogasawara and Japan trenches as well as parallel chains of islands and volcanoes, typical of the Circumpacific island arcs. Similarly, the Philippine Sea plate is itself subducting under the Eurasia plate along a zone, extending from Taiwan to southern Honshu, that comprises the Ryuku Islands and the Nansei-Shonto trench.

  5. Factors Influencing Japanese Women to Choose Two-Year Colleges in Japan

    ERIC Educational Resources Information Center

    Anzai, Shinobu; Paik, Chie Matsuzawa

    2012-01-01

    Two-year colleges in Japan have traditionally absorbed the major portion of female college entrants due to long-held gender stereotypes. Recently, Japanese women began to explore selfhood outside the traditional realm of marriage and motherhood. However, two-year colleges in Japan today continue to enroll mostly female students and few male…

  6. Ideologies of English in Japan: The Perspective of Policy and Pedagogy

    ERIC Educational Resources Information Center

    Seargeant, Philip

    2008-01-01

    This paper examines the ideologies of language which underpin mainstream applied linguistic research and educational policy generation for English language teaching in Japan. Over the last 30 years a burgeoning literature has devoted itself to the task of researching and directing English language education in Japan, but has, by its own admission,…

  7. Geologic Evidence of Tsunamigenic Earthquakes from the Southern Part of the Japan Trench

    NASA Astrophysics Data System (ADS)

    Pilarczyk, J.; Sawai, Y.; Namegaya, Y.; Tamura, T.; Tanigawa, K.; Matsumoto, D.; Shinozaki, T.; Fujiwara, O.; Shishikura, M.; Shimada, Y.; Dura, T.; Horton, B.

    2017-12-01

    The northern and southern parts of the Japan Trench have generated earthquakes with moment magnitudes up to 8.0. Similarly, the middle part of the Japan Trench has historically generated tsunamigenic-earthquakes up to M 7.0. However, in 2011, the Tohoku-oki (M 9.0) event ruptured 500 km along the middle part of the Japan Trench and generated the largest known tsunami to have originated from this part of the subduction zone. Seismic models indicate that the Tohoku-oki earthquake may have transferred stress southwards down the fault to the potentially locked southern part of the Japan Trench. It is unknown if this transfer of stress could produce an earthquake and tsunami that would impact the metropolitan areas of east-central Japan in the near future that may be comparable in magnitude to the Tohoku-oki event. Here, we reconstruct the history of individual great earthquakes and accompanying tsunamis using geological records from the coastal zone adjacent to the southern part of the Japan Trench, providing an assessment of the seismic hazard for metropolitan areas in east-central Japan. In the Kujukuri strand plain, we found three anomalous marine sand layers intercalated within muddy peat, which can be traced 3.8 km inland and 50 km along the present Kujukuri coastline. Each sand layer has features consistent with tsunami deposits, such as a distinct erosional base, rip-up clasts, normal grading, and a mud drape. Preliminary radiocarbon dating suggests three tsunamis inundated the Kujukuri coastline over the last millennium.

  8. The characteristics of patient safety culture in Japan, Taiwan and the United States.

    PubMed

    Fujita, Shigeru; Seto, Kanako; Ito, Shinya; Wu, Yinghui; Huang, Chiu-Chin; Hasegawa, Tomonori

    2013-01-14

    Quality and safety issues are receiving growing attention. Patient safety culture (PSC) plays an important role in patient safety. The characteristics of PSC in various countries, each with a different set of values, have not been determined sufficiently. The aim of this study is to investigate the characteristics of PSC in Japan, Taiwan and the U.S. A cross-sectional survey was conducted in Japan and Taiwan using the Hospital Survey on PSC (HSOPS) questionnaire developed by the U.S. Agency for Healthcare Research and Quality (AHRQ). Data from Japan and Taiwan were also compared with the U.S. "2010 HSOPS Comparative Database" provided by AHRQ. Valid response rates in Japan, Taiwan and the U.S. were 66.5% (6,963/10,466), 85.7% (10,019/11,692) and 35.2% (291,341/827,424), respectively. The proportion of respondents with some experience of event reporting during the past 12 months was highest in Japan. In general, U.S. healthcare workers were likely to evaluate their PSC higher than that in Japan or Taiwan. The attitude of continuous improvement in Japan and event reporting of near misses in Taiwan were rated as low. In the U.S., staffing was rated as high. The results suggest that PSC varies among different countries, and the cultural setting of each country should be given special consideration in the development of effective intervention plans to improve PSC. Additional investigations with improved methodology and a common protocol are required to accurately compare PSCs among countries.

  9. Transforming healthcare with information technology in Japan: a review of policy, people, and progress.

    PubMed

    Abraham, Chon; Nishihara, Eitaro; Akiyama, Miki

    2011-03-01

    Healthcare reform as part of the economic recovery plan in Japan is placing emphasis on the use of healthcare information technology (HIT). This research mainly focuses on the HIT efforts in Japan with reference to the US for context. The purpose is to: (a) provide detail on governmental policy impacting promotion of HIT adoption to provide services to the people of Japan, (b) describe the outcomes of past and present policy impacting progress based on a case study of HIT use in the Kyoto Yamashina area, and (c) discuss issues for refinement of current policy. The method is case study, and data collection techniques include: (a) interviews of people involved in policy making for HIT in Japan (Japanese healthcare professionals, government officials, and academics involved in HIT research in Japan) and use in the medical community of HIT in the Kyoto Yamashina area, (b) archived document analysis of reports regarding government policy for HIT policy and user assessment for HIT mainly in the case study site, and (c) the literature review about HIT progression and effectiveness assessments to explore and describe issues concerning the transformation with HIT in Japan. This study reveals the aspects of governmental policy that have been effective in promoting successful HIT initiatives as well as some that have been detriments in Japan to help solve pressing social issues regarding healthcare delivery. For example, Japan has stipulated some standardized protocols and formats for HIT but does not mandate exactly how to engage in inter-organizational or intra-organizational health information exchange. This provides some desired autonomy for healthcare organizations and or governments in medical communities and allows for more advanced organizations to leverage current resources while providing a basis for lesser equipped organizations to use in planning the initiative. The insights gained from the Kyoto Yamashina area initiative reflect the success of past governmental

  10. 78 FR 23905 - Diffusion-Annealed, Nickel-Plated Flat-Rolled Steel Products From Japan: Initiation of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-23

    ...-Plated Flat-Rolled Steel Products From Japan: Initiation of Antidumping Duty Investigation AGENCY: Import... products from Japan (``certain nickel-plated, flat-rolled steel''), filed in proper form by Thomas Steel... Antidumping Duty Petition on Diffusion-Annealed, Nickel- Plated Steel Flat-Rolled Products from Japan, dated...

  11. Lesson Plans for a Secondary Level Unit on Japan To Accompany "Contemporary Japan: A Teaching Workbook."

    ERIC Educational Resources Information Center

    Tsunoda, Elizabeth P.; And Others

    These 30 lesson plans were designed to accompany "Contemporary Japan: A Teaching Workbook", a collection of class activities, primary source selections, student readings, and role-play exercises. The lesson plans are based primarily on materials in the workbook, although materials from other sources also are recommended. Some of the…

  12. Using Multigroup-Multiphase Latent State-Trait Models to Study Treatment-Induced Changes in Intra-Individual State Variability: An Application to Smokers' Affect.

    PubMed

    Geiser, Christian; Griffin, Daniel; Shiffman, Saul

    2016-01-01

    Sometimes, researchers are interested in whether an intervention, experimental manipulation, or other treatment causes changes in intra-individual state variability. The authors show how multigroup-multiphase latent state-trait (MG-MP-LST) models can be used to examine treatment effects with regard to both mean differences and differences in state variability. The approach is illustrated based on a randomized controlled trial in which N = 338 smokers were randomly assigned to nicotine replacement therapy (NRT) vs. placebo prior to quitting smoking. We found that post quitting, smokers in both the NRT and placebo group had significantly reduced intra-individual affect state variability with respect to the affect items calm and content relative to the pre-quitting phase. This reduction in state variability did not differ between the NRT and placebo groups, indicating that quitting smoking may lead to a stabilization of individuals' affect states regardless of whether or not individuals receive NRT.

  13. [WHO Healthy City Initiative in Japan].

    PubMed

    Yoshizawa, Kazuko

    2013-01-01

    City environmental conditions are associated with health outcomes in people living there. World Health Organization (WHO) initiated Healthy City in 1986. To promote the networking, Alliance for Healthy Cities (AFHC) was launched in 2003 with local offices including AFHC Japan. As of 2010, 26 cities are members of AFHC Japan. A questionnaire was sent to those member cities. It includes questions on why they became an AFHC member, which section is in charge of the initiatives, what factors are important for promotion, and others. Out of the 26 cities, 13 cities returned the completed questionnaire. As for factors important for promoting the initiatives, 10 (77%) out of the 13 cities answered "consciousness of residents", while five (38%) chose "budget". This result suggests that community participation is a more important factor than budget for promoting and succeeding in the initiatives. Aging is a problem in any of the member cities, and six cities out the 13 falls under the category of superaged society, which is defined as a society with the proportion of aged people < 65 years being greater than 21% of the whole population. Eleven cities (85%) agreed that bicycles are an alternative means of transportation to cars; however, infrastructure for ensuring safety needs further improvement. In the promotion of Healthy City, networking among the member cities in Japan and worldwide should be promoted. Community participation with empowerment from the planning stage should lead to sustainable initiatives. The function of AFHC in collaboration among the members should be strengthened to cope with the rapidly changing city environment.

  14. 78 FR 64477 - Welded Large Diameter Line Pipe From Japan: Continuation of Antidumping Duty Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-29

    ... Pipe From Japan: Continuation of Antidumping Duty Order AGENCY: Enforcement and Compliance, Formerly...) from Japan would likely lead to continuation or recurrence of dumping and material injury to an... Department published the antidumping duty order on LDLP from Japan.\\1\\ On October 1, 2012, the Department...

  15. Epidemiology of rubella and congenital rubella syndrome in Japan before 1989.

    PubMed

    Ueda, Kohji

    2016-04-07

    Epidemiological studies of rubella and congenital rubella syndrome (CRS) in Japan have been conducted since the first nationwide rubella epidemic of 1965-1969 and subsequent epidemics of 1975-1977, 1982, 1987-1988, and 1992-1993. Rubella was non-endemic in Japan before the 1975-1977 epidemic, and endemic thereafter. Japan started a selective rubella vaccination program for junior high school girls in 1977, and universal rubella vaccination of children of both sexes in 1989. No nationwide rubella epidemics have occurred since 1994. Only three children with CRS were reported in Japan before 1964; however, many children with CRS were identified in 1965 when a rubella epidemic struck Okinawa, which has many the United States military bases. After the 1965-1969 and 1975-1977 rubella epidemics on the Japanese mainland, small numbers of children with CRS were identified (hospital survey). These findings led to the hypothesis that, compared to U.S. rubella virus strains, Japanese strains of rubella virus are less teratogenic. This hypothesis strongly affected the development of rubella vaccines in Japan. However, retrospective seroepidemiological studies attributed the CRS in many children in Okinawa to the high rate of rubella infection in pregnant women. According to the survey conducted at special schools for the deaf, 83, 232, 77, and 167 children were born with CRS on the Japanese mainland respectively after the 1965-1969, 1975-1977, 1982, and 1987-1988 nationwide rubella epidemics, suggesting that the incidence of CRS in Japan is in fact comparable to that in the U.S. and Europe. Rubella epidemics in children have been effectively prevented since 1994. However, a rubella outbreak among adult males and CRS occurred between 2012 and 2014. Copyright © 2015 Elsevier Ltd. All rights reserved.

  16. Japanese Fundraising: A Comparative Study of the United States and Japan

    ERIC Educational Resources Information Center

    Onishi, Tamaki

    2007-01-01

    The enactment of the Law to Promote Specified Nonprofit Activities in 1998 has resulted not only in a rapid increase in the number of specified nonprofit corporations (NPO corporations) but also in an urgent need for effective fundraising in Japan. Despite Japan's long and rich tradition of philanthropy and a serious need for fundraising, very…

  17. Policy review: Japan-Philippines Economic Partnership Agreement (JPEPA)--analysis of a failed nurse migration policy.

    PubMed

    Yagi, Nozomi; Mackey, Tim K; Liang, Bryan A; Gerlt, Lorna

    2014-02-01

    In 2008, the bilateral Japan-Philippines Economic Partnership Agreement took effect. Contained within this regional free trade agreement are unique provisions allowing exchange of Filipino nurses and healthcare workers to work abroad in Japan. Japan's increasing need for healthcare workers due to its aging demographic and the Philippines need for economic development could have led to shared benefits under the Japan-Philippines Economic Partnership Agreement. However, 4 years following program implementation, results have been disappointing, e.g., only 7% of candidates passing the programs requirements since 2009. These disappointing results represent a policy failure within the current Japan-Philippines Economic Partnership Agreement framework, and point to the need for reform. Hence, amending the current Japan-Philippines Economic Partnership Agreement structure by potentially adopting a USA based approach to licensure examinations and implementing necessary institutional and governance reform measures may be necessary to ensure beneficial healthcare worker migration for both countries. Copyright © 2013 Elsevier Ltd. All rights reserved.

  18. [The Chinese nuclear test and 'atoms for peace' as a measure for preventing nuclear armament of Japan: the nuclear non-proliferation policy of the United States and the introduction of light water reactors into Japan, 1964-1968].

    PubMed

    Yamazaki, Masakatsu

    2014-07-01

    Japan and the United States signed in 1968 a new atomic energy agreement through which US light-water nuclear reactors, including those of the Fukushima Daiichi Nuclear Power Plant of Tokyo Electric Power Company, were to be introduced into Japan. This paper studies the history of negotiations for the 1968 agreement using documents declassified in the 1990s in the US and Japan. After the success of the Chinese nuclear test in October 1964, the United States became seriously concerned about nuclear armament of other countries in Asia including Japan. Expecting that Japan would not have its own nuclear weapons, the US offered to help the country to demonstrate its superiority in some fields of science including peaceful nuclear energy to counter the psychological effect of the Chinese nuclear armament. Driven by his own political agenda, the newly appointed Prime Minister Eisaku Sato responded to the US expectation favorably. When he met in January 1965 with President Johnson, Sato made it clear that Japan would not pursue nuclear weapons. Although the US continued its support after this visit, it nevertheless gave priority to the control of nuclear technology in Japan through the bilateral peaceful nuclear agreement. This paper argues that the 1968 agreement implicitly meant a strategic measure to prevent Japan from going nuclear and also a tactic to persuade Japan to join the Nuclear Non -Proliferation Treaty.

  19. 76 FR 44503 - Availability of a Risk Analysis Evaluating the Foot-and-Mouth Disease Status of Japan

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-26

    ... Foot-and-Mouth Disease Status of Japan AGENCY: Animal and Plant Health Inspection Service, USDA. ACTION... disease (FMD) status of Japan and the risk of susceptible animals and animal products from Japan harboring... Health Inspection again recognizes Japan as free of FMD and allows the importation of whole cuts of...

  20. Generic antibiotics in Japan.

    PubMed

    Fujimura, Shigeru; Watanabe, Akira

    2012-08-01

    Generic drugs have been used extensively in many developed countries, although their use in Japan has been limited. Generic drugs reduce drug expenses and thereby national medical expenditure. Because generic drugs provide advantages for both public administration and consumers, it is expected that they will be more widely used in the future. However, the diffusion rate of generic drugs in Japan is quite low compared with that of other developed countries. An investigation on generic drugs conducted by the Ministry of Health, Labour and Welfare in Japan revealed that 17.2 % of doctors and 37.2 % of patients had not used generic drugs. The major reasons for this low use rate included distrust of off-patent products and lower drug price margin compared with the brand name drug. The generic drugs available in the market include external drugs such as wet packs, antihypertensive agents, analgesics, anticancer drugs, and antibiotics. Among them, antibiotics are frequently used in cases of acute infectious diseases. When the treatment of these infections is delayed, the infection might be aggravated rapidly. The pharmacokinetics-pharmacodynamics (PK-PD) theory has been adopted in recent chemotherapy, and in many cases, the most appropriate dosage and administration of antibiotics are determined for individual patients considering renal function; high-dosage antibiotics are used preferably for a short duration. Therefore, a highly detailed antimicrobial agent is necessary. However, some of the generic antibiotics have less antibacterial potency or solubility than the brand name products. We showed that the potency of the generic products of vancomycin and teicoplanin is lower than that of the branded drugs by 14.6 % and 17.3 %, respectively. Furthermore, we confirmed that a generic meropenem drug for injection required about 82 s to solubilize in saline, whereas the brand product required only about 21 s. It was thought that the cause may be the difference in size of bulk