The Audiovisual Temporal Binding Window Narrows in Early Childhood

ERIC Educational Resources Information Center

Lewkowicz, David J.; Flom, Ross

2014-01-01

Binding is key in multisensory perception. This study investigated the audio-visual (A-V) temporal binding window in 4-, 5-, and 6-year-old children (total N = 120). Children watched a person uttering a syllable whose auditory and visual components were either temporally synchronized or desynchronized by 366, 500, or 666 ms. They were asked…

Protective broadband window coatings

NASA Astrophysics Data System (ADS)

Askinazi, Joel; Narayanan, Authi A.

1997-06-01

Optical windows employed in current and future airborne and ground based optical sensor systems are required to provide long service life under extreme environmental conditions including blowing sand and high speed rain. State of the art sensor systems are employing common aperture windows which must provide optical bandpasses from the TV to the LWIR. Operation Desert Storm experience indicates that current optical coatings provide limited environmental protection which adversely affects window life cycle cost. Most of these production coatings also have limited optical bandpasses (LWIR, MWIR, or TV-NIR). A family of optical coatings has been developed which provide a significant increase in rain and sand impact protection to current optical window materials. These coatings can also be tailored to provide either narrow optical bandwidth (e.g., LWIR) or broadband transmittance (TV- LWIR). They have been applied to a number of standard optical window materials. These coating have successfully completed airborne rain and sand abrasion test with minimal impact on optical window performance. Test results are presented. Low cost service life is anticipated as well as the ability to operate windows in even more taxing environments than currently feasible.

Constructivist developmental theory is needed in developmental neuroscience

NASA Astrophysics Data System (ADS)

Arsalidou, Marie; Pascual-Leone, Juan

2016-12-01

Neuroscience techniques provide an open window previously unavailable to the origin of thoughts and actions in children. Developmental cognitive neuroscience is booming, and knowledge from human brain mapping is finding its way into education and pediatric practice. Promises of application in developmental cognitive neuroscience rests however on better theory-guided data interpretation. Massive amounts of neuroimaging data from children are being processed, yet published studies often do not frame their work within developmental models—in detriment, we believe, to progress in this field. Here we describe some core challenges in interpreting the data from developmental cognitive neuroscience, and advocate the use of constructivist developmental theories of human cognition with a neuroscience interpretation.

Narrowing the window of inflationary magnetogenesis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Markkanen, Tommi; Nurmi, Sami; Räsänen, Syksy

2017-06-01

We consider inflationary magnetogenesis where the conformal symmetry is broken by the term f {sup 2}(φ) F {sub αβ} F {sup αβ}. We assume that the magnetic field power spectrum today between 0.1 and 10{sup 4} Mpc is a power law, with upper and lower limits from observation. This fixes f to be close to a power law in conformal time in the window during inflation when the modes observed today are generated. In contrast to previous work, we do not make any assumptions about the form of f outside these scales. We cover all possible reheating histories, described bymore » an average equation of state −1/3 < w-bar < 1. Requiring that strong coupling and large backreaction are avoided both at the background and perturbative level, we find the bound δ {sub B} {sub 0} < 5 ×10{sup −15} ( r /0.07){sup 1/2} κG for the magnetic field generated by inflation, where r is the tensor-to-scalar ratio and κ is a constant related to the form of f . This estimate has an uncertainty of one order of magnitude related to our approximations. The parameter κ is < 100, and values ∼> 1 require a highly fine-tuned form of f ; typical values are orders of magnitude smaller.« less

Adaptive variability in the duration of critical windows of plasticity

PubMed Central

Wells, Jonathan C. K.

2014-01-01

Developmental plasticity underlies widespread associations between early-life exposures and many components of adult phenotype, including the risk of chronic diseases. Humans take almost two decades to reach reproductive maturity, and yet the ‘critical windows’ of physiological sensitivity that confer developmental plasticity tend to close during fetal life or infancy. While several explanations for lengthy human maturation have been offered, the brevity of physiological plasticity has received less attention. I argue that offspring plasticity is only viable within the niche of maternal care, and that as this protection is withdrawn, the offspring is obliged to canalize many developmental traits in order to minimize environmental disruptions. The schedule of maternal care may therefore shape the duration of critical windows, and since the duration of this care is subject to parent–offspring conflict, the resolution of this conflict may shape the duration of critical windows. This perspective may help understand (i) why windows close at different times for different traits, and (ii) why the duration of critical windows may vary across human populations. The issue is explored in relation to population differences in the association between infant weight gain and later body composition. The occupation of more stable environments by western populations may have favoured earlier closure of the critical window during which growth in lean mass is sensitive to nutritional intake. This may paradoxically have elevated the risk of obesity following rapid infant weight gain in such populations. PMID:25095791

Developmental Audits with Challenging Youth

ERIC Educational Resources Information Center

Brendtro, Larry K.; du Toit, Lesley; Bath, Howard; Van Bockern, Steve

2006-01-01

The Developmental Audit[R] is a new strength-based assessment model for youth who are in conflict in home, school, or community. Developmental Audits involve collaboration with young persons who are seen as experts on themselves. Discussing challenging life events provides a window to the young person's private logic and goals. The audit scans…

Age Differences in Prenatal Testosterone's Protective Effects on Disordered Eating Symptoms: Developmental Windows of Expression?

PubMed Central

Culbert, Kristen M.; Breedlove, S. Marc; Sisk, Cheryl L.; Keel, Pamela K.; Neale, Michael C.; Boker, Steven M.; Burt, S. Alexandra; Klump, Kelly L.

2015-01-01

Prenatal testosterone exposure may be protective against disordered eating. However, prior studies have produced mixed results. Developmental differences in prenatal testosterone's protective effects on disordered eating may explain these discrepancies. Indeed, studies have differed in the age of participants assessed, with data supporting prenatal testosterone effects on disordered eating in early adolescent and young adult samples but not in late adolescence. The present series of studies are the first to investigate age differences in prenatal testosterone's protective effects on disordered eating. Two indirect markers of higher prenatal testosterone were examined: 1) lower finger-length ratios [index (2D)/ring (4D) finger] (Study 1), and 2) lower disordered eating in females from opposite-sex twin pairs (who are thought to be exposed to higher prenatal testosterone from their male co-twin) relative to female controls (Study 2). Participants were twins from the Michigan State University Twin Registry (Study 1: n = 409; Study 2: n = 1,538) in early adolescence, late adolescence, or young adulthood. Disordered eating was assessed with well-validated questionnaires. Finger-length ratios were measured from hand scans, using electronic computer calipers. Findings were consistent across both studies. Higher prenatal testosterone (lower 2D:4D; females from opposite-sex twin pairs vs. controls) predicted lower disordered eating in early adolescence and young adulthood only. Prenatal testosterone-disordered eating associations were not observed during late adolescence. Results point to the possibility of developmental windows of expression for prenatal testosterone's protective effects on disordered eating and suggest that prior discrepant results may reflect age differences across samples. PMID:25621790

9. INTERIOR LIVING ROOM DETAIL OF ONE OF TWO NARROW ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

9. INTERIOR LIVING ROOM DETAIL OF ONE OF TWO NARROW 4-LIGHT OVER 4-LIGHT, DOUBLE-HUNG, WOOD-FRAMED WINDOWS ON EITHER SIDE OF FRONT DOOR SHOWING EXPOSED COUNTERBALANCE CABLE. VIEW TO SOUTHWEST. - Bishop Creek Hydroelectric System, Plant 4, Worker Cottage, Bishop Creek, Bishop, Inyo County, CA

Developmental windows of breast cancer risk provide opportunities for targeted chemoprevention

PubMed Central

Martinson, Holly A.; Lyons, Traci R.; Giles, Erin D.; Borges, Virginia F.; Schedin, Pepper

2014-01-01

The magnitude of the breast cancer problem implores researchers to aggressively investigate prevention strategies. However, several barriers currently reduce the feasibility of breast cancer prevention. These barriers include the inability to accurately predict future breast cancer diagnosis at the individual level, the need for improved understanding of when to implement interventions, uncertainty with respect to optimal duration of treatment, and negative side effects associated with currently approved chemoprevention therapies. None-the-less, the unique biology of the mammary gland, with its postnatal development and conditional terminal differentiation, may permit the resolution of many of these barriers. Specifically, lifecycle-specific windows of breast cancer risk have been identified that may be amenable to risk-reducing strategies. Here, we argue for prevention research focused on two of these lifecycle windows of risk: postpartum mammary gland involution and peri-menopause. We provide evidence that these windows are highly amenable to targeted, limited duration treatments. Such approaches could result in the prevention of postpartum and postmenopausal breast cancers, correspondingly. PMID:23664839

Tunable Narrow Band Emissions from Dye-Sensitized Core/Shell/Shell Nanocrystals in the Second Near-Infrared Biological Window

PubMed Central

Shao, Wei; Chen, Guanying; Kuzmin, Andrey; Kutscher, Hilliard L.; Pliss, Artem; Ohulchanskyy, Tymish Y.; Prasad, Paras N.

2017-01-01

We introduce a hybrid organic–inorganic system consisting of epitaxial NaYF4:Yb3+/X3+@NaYbF4@NaYF4:Nd3+ (X = null, Er, Ho, Tm, or Pr) core/shell/shell (CSS) nanocrystal with organic dye, indocyanine green (ICG) on the nanocrystal surface. This system is able to produce a set of narrow band emissions with a large Stokes-shift (>200 nm) in the second biological window of optical transparency (NIR-II, 1000–1700 nm), by directional energy transfer from light-harvesting surface ICG, via lanthanide ions in the shells, to the emitter X3+ in the core. Surface ICG not only increases the NIR-II emission intensity of inorganic CSS nanocrystals by ~4-fold but also provides a broadly excitable spectral range (700–860 nm) that facilitates their use in bioapplications. We show that the NIR-II emission from ICG-sensitized Er3+-doped CSS nanocrystals allows clear observation of a sharp image through 9 mm thick chicken breast tissue, and emission signal detection through 22 mm thick tissue yielding a better imaging profile than from typically used Yb/Tm-codoped upconverting nanocrystals imaged in the NIR-I region (700–950 nm). Our result on in vivo imaging suggests that these ICG-sensitized CSS nanocrystals are suitable for deep optical imaging in the NIR-II region. PMID:27935695

Active two-phase cooling of an IR window for a hypersonic interceptor

NASA Astrophysics Data System (ADS)

Burzlaff, B. H.; Chivian, Jay S.; Cotten, W. D.; Hemphill, R. B.; Huhlein, Michael A.

1993-06-01

A novel actively cooled window for an IR sensor on a hypersonic interceptor is envisioned which achieves an IR window with high transmittance, low emittance, and low image distortion under high aerodynamic heat flux. The cooling concept employs two-phase convective boiling of liquid ammonia. Coolant is confined to narrow, parallel channels within the window to minimize obscuration of the aperture. The high latent heat of vaporization of ammonia minimizes coolant mass-flow requirements. Low boiling temperatures at projected operating pressures promote high thermal conductivity and low emissivity in the window. The concept was tested with thermal measurements on sub-mm width coolant channels in Si. High values for heat transfer coefficient and critical heat flux were obtained. Thermal gradients within the window can be controlled by the coolant channel configuration. Design options are investigated by predicting the effect of aerodynamic heat flux on the image produced by an IR sensor with a cooled window. Ammonia-cooled IR windows will function in the anticipated aerothermal environment.

Developmental spinal canal stenosis and somatotype.

PubMed Central

Nightingale, S

1989-01-01

The hypothesis that somatotype and cervical spine developmental canal stenosis may be associated has been investigated by anthropometry and measurement of lateral projection cervical spine radiographs. A significant association of canal size with somatotype has been found such that those with developmentally narrow canals are more likely to have relatively shorter long-bones, particularly in the upper arm, and longer trunks. Images PMID:2769282

Adaptive variability in the duration of critical windows of plasticity: Implications for the programming of obesity.

PubMed

Wells, Jonathan C K

2014-08-05

Developmental plasticity underlies widespread associations between early-life exposures and many components of adult phenotype, including the risk of chronic diseases. Humans take almost two decades to reach reproductive maturity, and yet the 'critical windows' of physiological sensitivity that confer developmental plasticity tend to close during fetal life or infancy. While several explanations for lengthy human maturation have been offered, the brevity of physiological plasticity has received less attention. I argue that offspring plasticity is only viable within the niche of maternal care, and that as this protection is withdrawn, the offspring is obliged to canalize many developmental traits in order to minimize environmental disruptions. The schedule of maternal care may therefore shape the duration of critical windows, and since the duration of this care is subject to parent-offspring conflict, the resolution of this conflict may shape the duration of critical windows. This perspective may help understand (i) why windows close at different times for different traits, and (ii) why the duration of critical windows may vary across human populations. The issue is explored in relation to population differences in the association between infant weight gain and later body composition. The occupation of more stable environments by western populations may have favoured earlier closure of the critical window during which growth in lean mass is sensitive to nutritional intake. This may paradoxically have elevated the risk of obesity following rapid infant weight gain in such populations. © The Author(s) 2014. Published by Oxford University Press on behalf of the Foundation for Evolution, Medicine, and Public Health.

Developmental origins of epigenetic transgenerational inheritance

PubMed Central

Hanson, Mark A.; Skinner, Michael K.

2016-01-01

Abstract Environmental factors can induce epigenetic alterations in the germ cells that can potentially be transmitted transgenerationally. This non-genetic form of inheritance is termed epigenetic transgenerational inheritance and has been shown in a variety of species including plants, flies, worms, fish, rodents, pigs, and humans. This phenomenon operates during specific critical windows of exposure, linked to the developmental biology of the germ cells (sperm and eggs). Therefore, concepts of the developmental origins of transgenerational inheritance of phenotypic variation and subsequent disease risk need to include epigenetic processes affecting the developmental biology of the germ cell. These developmental impacts on epigenetic transgenerational inheritance, in contrast to multigenerational exposures, are the focus of this Perspective. PMID:27390622

Understanding Windows | Efficient Windows Collaborative

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Transparency of 2μ m window of Titan's atmosphere

NASA Astrophysics Data System (ADS)

Rannou, P.; Seignovert, B.; Le Mouélic, S.; Maltagliati, L.; Rey, M.; Sotin, C.

2018-02-01

Titan's atmosphere is optically thick and hides the surface and the lower layers from the view at almost all wavelengths. However, because gaseous absorptions are spectrally selective, some narrow spectral intervals are relatively transparent and allow to probe the surface. To use these intervals (called windows) a good knowledge of atmospheric absorption is necessary. Once gas spectroscopic linelists are well established, the absorption inside windows depends on the way the far wings of the methane absorption lines are cut-off. We know that the intensity in all the windows can be explained with the same cut-off parameters, except for the window at 2 μm. This discrepancy is generally treated with a workaround which consists in using a different cut-off description for this specific window. This window is relatively transparent and surface may have specific spectral signatures that could be detected. Thus, a good knowledge of atmosphere opacities is essential and our scope is to better understand what causes the difference between the 2 μm window and the other windows. In this work, we used scattered light at the limb and transmissions in occultation observed with VIMS (Visual Infrared Mapping Spectrometer) onboard Cassini, around the 2 μm window. Data shows an absorption feature that participates to the shape of this window. Our atmospheric model fits well the VIMS data at 2 μm with the same cut-off than for the other windows, provided an additional absorption is introduced in the middle of the window around ≃ 2.065 μm. It explains well the discrepency between the cut-off used at 2 μm, and we show that a gas with a fairly constant mixing ratio, possibly ethane, may be the cause of this absorption. Finally, we studied the impact of this absorption on the retrieval of the surface reflectivity and found that it is significant.

Self-Sustained Mode-3 Tear Controls Dynamics of Narrow Retreating Subduction Zones

NASA Astrophysics Data System (ADS)

Munch, J.; Gerya, T.; Ueda, K.

2017-12-01

The Caribbean oroclinal basin exhibits several narrow retreating slabs in an oceanic domain. The slabs show a curved shape associated to a bent topography (trench). We propose that the curvature of the topography depends on slab retreat mechanisms following mode-3 tearing at the edges of the slab (out of the plane fracture propagation). While first-order characteristics have been principally reproduced in self-sustained subduction initiation models (Gerya et al., 2015, Nature, 527, 221-225), the relevant observations have not been quantified and the exact mechanism is not understood. In this work, we study the long-term 3D evolution of narrowing oceanic subduction zones during retreat, and investigate the link between mode-3 tear and orocline formation. Numerical experiments are carried out with a thermo-mechanical 3D finite-difference code. To allow the observation of developing topography, the precise location of the internal surface and its evolution by material diffusion is tracked. Retreating subduction is facilitated via a strong age contrast between a young lithosphere window enclosed by shear zones and the surrounding lithosphere. By varying the length and thickness of the shear zones and location of the age transition, the influence of these parameters on the tearing process and the development of topography is assessed. Experiments trigger subduction initiation and slab retreat via fracture zone collapse and spontaneous paired mode-3 tear propagation within the oceanic plate interior. Narrow retreating subducting slabs form as a natural result of the spontaneous paired tearing process. A curved trench forms along with slab retreat. Topography evolution and tearing trajectory appear to be dependent on the initial shear zones and young window dimensions. We also note a strong narrowing of the slab during the retreat (several tens of kilometers over 800 km of retreat). Overall, results indicate that narrowing of retreating slabs is a self

Interview with Violet Oaklander, Author of "Windows to Our Children."

ERIC Educational Resources Information Center

Campbell, Chari A.

1993-01-01

Presents interview with Dr. Violent Oaklander, experienced child therapist and author of "Windows to Our Children: A Gestalt Therapy with Children and Adolescents." Discusses critical components of successful therapy with children. Explains how developmental stage of child affects therapeutic process, and provides specific examples of working with…

Challenges and opportunities in developmental integrative physiology☆

PubMed Central

Mueller, C.A.; Eme, J.; Burggren, W.W.; Roghair, R.D.; Rundle, S.D.

2015-01-01

This review explores challenges and opportunities in developmental physiology outlined by a symposium at the 2014 American Physiological Society Intersociety Meeting: Comparative Approaches to Grand Challenges in Physiology. Across animal taxa, adverse embryonic/fetal environmental conditions can alter morphological and physiological phenotypes in juveniles or adults, and capacities for developmental plasticity are common phenomena. Human neonates with body sizes at the extremes of perinatal growth are at an increased risk of adult disease, particularly hypertension and cardiovascular disease. There are many rewarding areas of current and future research in comparative developmental physiology. We present key mechanisms, models, and experimental designs that can be used across taxa to investigate patterns in, and implications of, the development of animal phenotypes. Intraspecific variation in the timing of developmental events can be increased through developmental plasticity (heterokairy), and could provide the raw material for selection to produce heterochrony — an evolutionary change in the timing of developmental events. Epigenetics and critical windows research recognizes that in ovo or fetal development represent a vulnerable period in the life history of an animal, when the developing organism may be unable to actively mitigate environmental perturbations. ‘Critical windows’ are periods of susceptibility or vulnerability to environmental or maternal challenges, periods when recovery from challenge is possible, and periods when the phenotype or epigenome has been altered. Developmental plasticity may allow survival in an altered environment, but it also has possible long-term consequences for the animal. “Catch-up growth” in humans after the critical perinatal window has closed elicits adult obesity and exacerbates a programmed hypertensive phenotype (one of many examples of “fetal programing”). Grand challenges for developmental physiology

A Summary of the Evaluation of PPG Herculite XP Glass in Punched Window and Storefront Assemblies

DTIC Science & Technology

2013-01-01

frames for all IGU windows extruded from existing dies. The glazing was secured to the frame on all four sides with a 1/2-in bead width of DOW 995...lite and non-laminated IGU debris tests. A wood frame with a 4-in wide slit was placed behind the window to transform the debris cloud into a narrow...speed camera DIC Set-up laser deflection gauge shock tube window wood frame with slit high speed camerawell lit backdrop Debris Tracking Set-up laser

Compound windows of the Hénon-map

NASA Astrophysics Data System (ADS)

Lorenz, Edward N.

2008-08-01

For the two-parameter second-order Hénon map, the shapes and locations of the periodic windows-continua of parameter values for which solutions x0,x1,… can be stably periodic, embedded in larger regions where chaotic solutions or solutions of other periods prevail-are found by a random searching procedure and displayed graphically. Many windows have a typical shape, consisting of a central “body” from which four narrow “antennae” extend. Such windows, to be called compound windows, are often arranged in bands, to be called window streets, that are made up largely of small detected but poorly resolved compound windows. For each fundamental subwindow-the portion of a window where a fundamental period prevails-a stability measure U is introduced; where the solution is stable, |U|<1. Curves of constant U are found by numerical integration. Along one line in parameter space the Hénon-map reduces to the one-parameter first-order logistic map, and two antennae from each compound window intersect this line. The curves where U=1 and U=-1 that bound either antenna are close together within these intersections, but, as either curve with U=-1 leaves the line, it diverges from the curve where U=1, crosses the other curve where U=-1, and nears the other curve where U=1, forming another antenna. The region bounded by the numerically determined curves coincides with the subwindow as found by random searching. A fourth-degree equation for an idealized curve of constant U is established. Points in parameter space producing periodic solutions where x0=xm=0, for given values of m, are found to lie on Cantor sets of curves that closely fit the window streets. Points producing solutions where x0=xm=0 and satisfying a third condition, approximating the condition that xn be bounded as n→-∞, lie on curves, to be called street curves of order m, that approximate individual members of the Cantor set and individual window streets. Compound windows of period m+m‧ tend to

Round and Oval Window Anatomic Variability: Its Implication for the Vibroplasty Technique.

PubMed

Mancheño, Marta; Aristegui, Miguel; Sañudo, Jose Ramon

2017-06-01

The objective of this study is to evaluate the anatomical variability of round and oval window regions and its relationship with their closest structures, to determine its implication on the fitting and stabilization of the middle ear implant Vibrant Soundbridge. Variations of the anatomy of round and oval window regions were assessed in a total of 85 human dissected temporal bones. Afterward, we evaluated the adaptation and subsequent stabilization of the floating mass transducer (FMT) of the Vibrant Soundbridge in 67 cases in round window (RW) and in 22 cases in oval window (OW), and the influence that the variability of the different anatomical features examined had on this stabilization. We also assessed access and surgeon's view of the RW niche through the facial recess approach. Stabilization of the FMT in the RW was achieved in 53 (79%) of the 67 cases; we found that the less favorable anatomical conditions for stabilization were: membrane smaller than 1.5 mm, presence of a high jugular bulb and a narrow or very narrow RW niche. Frequently, two or more of these conditions happened simultaneously. In seven cases (22%) access to the RW through facial recess approach did not allow positioning the FMT in place. OW stabilization succeeded in 18 (82%) of the 22 cases. Round and oval window vibroplasty are difficult surgical techniques. To place the FMT directly on the OW may be easier as we do not have to drill the niche. In both regions there are some anatomical conditions that hinder fitting the FMT and even make it impossible. Once fitted, the main problem is to achieve good stabilization of the device.

Difference of auditory brainstem responses by stimulating to round and oval window in animal experiments.

PubMed

Lee, Jyung Hyun; Park, Hyo Soon; Wei, Qun; Kim, Myoung Nam; Cho, Jin-Ho

2017-01-02

ABSTACT To ensure the safety and efficacy of implantable hearing aids, animal experiments are an essential developmental procedure, in particular, auditory brainstem responses (ABRs) can be used to verify the objective effectiveness of implantable hearing aids. This study measured and compared the ABRs generated when applying the same vibration stimuli to an oval window and round window. The ABRs were measured using a TDT system 3 (TDT, USA), while the vibration stimuli were applied to a round window and oval window in 4 guinea pigs using a piezo-electric transducer with a proper contact tip. A paired t-test was used to determine any differences between the ABR amplitudes when applying the stimulation to an oval window and round window. The paired t-test revealed a significant difference between the ABR amplitudes generated by the round and oval window stimulation (t = 10.079, α < .0001). Therefore, the results confirmed that the biological response to round window stimulation was not the same as that to oval window stimulation.

Window Selection Tool | Efficient Windows Collaborative

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Critical developmental windows for morphology and hematology revealed by intermittent and continuous hypoxic incubation in embryos of quail (Coturnix coturnix).

PubMed

Burggren, Warren W; Elmonoufy, Nourhan A

2017-01-01

data indicate a critical developmental window for hypoxia susceptibility during the mid-embryonic period of development.

28. ROOM 211, VIEW TO THE SOUTHEAST. THE LONG NARROW ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

28. ROOM 211, VIEW TO THE SOUTHEAST. THE LONG NARROW SPACE HAS EXPOSED TRUSSWORK IN UNPAINTED WOOD AS DID ALL UPSTAIRS ROOMS IN THEIR ORIGINAL CONDITION. CLERESTORY WINDOWS ARE INTERSPERSED WITH VENTS ALONG BOTH LONG SIDES OF THE ROOM. WALLS HAVE WIDE WOOD PANELING THAT IS PAINTED, FLOORS ARE WOOD. DOORWAY IN SOUTHWEST WALL LEADS TO UNFINISHED ATTIC SPACE. - Presidio of San Francisco, Cavalry Stables, Cowles Street, between Lincoln Boulevard & McDowell Street, San Francisco, San Francisco County, CA

Narrowing the gap: effects of intervention on developmental trajectories in autism.

PubMed

Klintwall, Lars; Eldevik, Sigmund; Eikeseth, Svein

2015-01-01

Although still a matter of some debate, there is a growing body of research supporting Early and Intensive Behavioral Intervention as the intervention of choice for children with autism. Learning rate is an alternative to change in standard scores as an outcome measure in studies of early intervention. Learning rates can be displayed graphically as developmental trajectories, which are easy to understand and avoid some of the counter-intuitive properties of changes in standard scores. The data used in this analysis were from 453 children with autism, previously described by Eldevik et al. Children receiving Early and Intensive Behavioral Intervention exhibited significantly steeper developmental trajectories than children in the control group, in both intelligence and adaptive behaviors. However, there was a considerable variability in individual learning rates within the group receiving Early and Intensive Behavioral Intervention. This variability could partly be explained by the intensity of the treatment, partly by children's intake intelligence quotient age-equivalents. Age at intake did not co-vary with learning rate. © The Author(s) 2013.

A protein-dye hybrid system as a narrow range tunable intracellular pH sensor.

PubMed

Anees, Palapuravan; Sudheesh, Karivachery V; Jayamurthy, Purushothaman; Chandrika, Arunkumar R; Omkumar, Ramakrishnapillai V; Ajayaghosh, Ayyappanpillai

2016-11-18

Accurate monitoring of pH variations inside cells is important for the early diagnosis of diseases such as cancer. Even though a variety of different pH sensors are available, construction of a custom-made sensor array for measuring minute variations in a narrow biological pH window, using easily available constituents, is a challenge. Here we report two-component hybrid sensors derived from a protein and organic dye nanoparticles whose sensitivity range can be tuned by choosing different ratios of the components, to monitor the minute pH variations in a given system. The dye interacts noncovalently with the protein at lower pH and covalently at higher pH, triggering two distinguishable fluorescent signals at 700 and 480 nm, respectively. The pH sensitivity region of the probe can be tuned for every unit of the pH window resulting in custom-made pH sensors. These narrow range tunable pH sensors have been used to monitor pH variations in HeLa cells using the fluorescence imaging technique.

Spectral Engineering of Slow Light, Cavity Line Narrowing, and Pulse Compression

NASA Astrophysics Data System (ADS)

Sabooni, Mahmood; Li, Qian; Rippe, Lars; Mohan, R. Krishna; Kröll, Stefan

2013-11-01

More than 4 orders of magnitude of cavity-linewidth narrowing in a rare-earth-ion-doped crystal cavity, emanating from strong intracavity dispersion caused by off-resonant interaction with dopant ions, is demonstrated. The dispersion profiles are engineered using optical pumping techniques creating significant semipermanent but reprogrammable changes of the rare-earth absorption profiles. Several cavity modes are shown within the spectral transmission window. Several possible applications of this phenomenon are discussed.

Benefits of Efficient Windows | Efficient Windows Collaborative

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Windows for New Construction | Efficient Windows Collaborative

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Performance Standards for Windows | Efficient Windows Collaborative

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Assessing Window Replacement Options | Efficient Windows Collaborative

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Calculation of Retention Time Tolerance Windows with Absolute Confidence from Shared Liquid Chromatographic Retention Data

PubMed Central

Boswell, Paul G.; Abate-Pella, Daniel; Hewitt, Joshua T.

2015-01-01

Compound identification by liquid chromatography-mass spectrometry (LC-MS) is a tedious process, mainly because authentic standards must be run on a user’s system to be able to confidently reject a potential identity from its retention time and mass spectral properties. Instead, it would be preferable to use shared retention time/index data to narrow down the identity, but shared data cannot be used to reject candidates with an absolute level of confidence because the data are strongly affected by differences between HPLC systems and experimental conditions. However, a technique called “retention projection” was recently shown to account for many of the differences. In this manuscript, we discuss an approach to calculate appropriate retention time tolerance windows for projected retention times, potentially making it possible to exclude candidates with an absolute level of confidence, without needing to have authentic standards of each candidate on hand. In a range of multi-segment gradients and flow rates run among seven different labs, the new approach calculated tolerance windows that were significantly more appropriate for each retention projection than global tolerance windows calculated for retention projections or linear retention indices. Though there were still some small differences between the labs that evidently were not taken into account, the calculated tolerance windows only needed to be relaxed by 50% to make them appropriate for all labs. Even then, 42% of the tolerance windows calculated in this study without standards were narrower than those required by WADA for positive identification, where standards must be run contemporaneously. PMID:26292624

Calculation of retention time tolerance windows with absolute confidence from shared liquid chromatographic retention data.

PubMed

Boswell, Paul G; Abate-Pella, Daniel; Hewitt, Joshua T

2015-09-18

Compound identification by liquid chromatography-mass spectrometry (LC-MS) is a tedious process, mainly because authentic standards must be run on a user's system to be able to confidently reject a potential identity from its retention time and mass spectral properties. Instead, it would be preferable to use shared retention time/index data to narrow down the identity, but shared data cannot be used to reject candidates with an absolute level of confidence because the data are strongly affected by differences between HPLC systems and experimental conditions. However, a technique called "retention projection" was recently shown to account for many of the differences. In this manuscript, we discuss an approach to calculate appropriate retention time tolerance windows for projected retention times, potentially making it possible to exclude candidates with an absolute level of confidence, without needing to have authentic standards of each candidate on hand. In a range of multi-segment gradients and flow rates run among seven different labs, the new approach calculated tolerance windows that were significantly more appropriate for each retention projection than global tolerance windows calculated for retention projections or linear retention indices. Though there were still some small differences between the labs that evidently were not taken into account, the calculated tolerance windows only needed to be relaxed by 50% to make them appropriate for all labs. Even then, 42% of the tolerance windows calculated in this study without standards were narrower than those required by WADA for positive identification, where standards must be run contemporaneously. Copyright © 2015 Elsevier B.V. All rights reserved.

Detection with Enhanced Energy Windowing Phase I Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bass, David A.; Enders, Alexander L.

2016-12-01

This document reviews the progress of Phase I of the Detection with Enhanced Energy Windowing (DEEW) project. The DEEW project is the implementation of software incorporating an algorithm which reviews data generated by radiation portal monitors and utilizes advanced and novel techniques for detecting radiological and fissile material while not alarming on Naturally Occurring Radioactive Material. Independent testing indicated that the Enhanced Energy Windowing algorithm showed promise at reducing the probability of alarm in the stream of commerce compared to existing algorithms and other developmental algorithms, while still maintaining adequate sensitivity to threats. This document contains a brief description ofmore » the project, instructions for setting up and running the applications, and guidance to help make reviewing the output files and source code easier.« less

Evaluation of an Out-of-the-Window Air Traffic Control Tower Simulation for Controller Training

DOT National Transportation Integrated Search

1996-09-01

This study gathered evidence concerning the potential usefulness of out-of-the-window air traffic control tower : simulation for training tower controllers. Data were collected from all ten developmental controllers who completed : simulation trainin...

Windows of sensitivity to toxic chemicals in the motor effects development.

PubMed

Ingber, Susan Z; Pohl, Hana R

2016-02-01

Many chemicals currently used are known to elicit nervous system effects. In addition, approximately 2000 new chemicals introduced annually have not yet undergone neurotoxicity testing. This review concentrated on motor development effects associated with exposure to environmental neurotoxicants to help identify critical windows of exposure and begin to assess data needs based on a subset of chemicals thoroughly reviewed by the Agency for Toxic Substances and Disease Registry (ATSDR) in Toxicological Profiles and Addenda. Multiple windows of sensitivity were identified that differed based on the maturity level of the neurological system at the time of exposure, as well as dose and exposure duration. Similar but distinct windows were found for both motor activity (GD 8-17 [rats], GD 12-14 and PND 3-10 [mice]) and motor function performance (insufficient data for rats, GD 12-17 [mice]). Identifying specific windows of sensitivity in animal studies was hampered by study designs oriented towards detection of neurotoxicity that occurred at any time throughout the developmental process. In conclusion, while this investigation identified some critical exposure windows for motor development effects, it demonstrates a need for more acute duration exposure studies based on neurodevelopmental windows, particularly during the exposure periods identified in this review. Published by Elsevier Inc.

Windows of sensitivity to toxic chemicals in the motor effects development✩

PubMed Central

Ingber, Susan Z.; Pohl, Hana R.

2017-01-01

Many chemicals currently used are known to elicit nervous system effects. In addition, approximately 2000 new chemicals introduced annually have not yet undergone neurotoxicity testing. This review concentrated on motor development effects associated with exposure to environmental neurotoxicants to help identify critical windows of exposure and begin to assess data needs based on a subset of chemicals thoroughly reviewed by the Agency for Toxic Substances and Disease Registry (ATSDR) in Toxicological Profiles and Addenda. Multiple windows of sensitivity were identified that differed based on the maturity level of the neurological system at the time of exposure, as well as dose and exposure duration. Similar but distinct windows were found for both motor activity (GD 8–17 [rats], GD 12–14 and PND 3–10 [mice]) and motor function performance (insufficient data for rats, GD 12–17 [mice]). Identifying specific windows of sensitivity in animal studies was hampered by study designs oriented towards detection of neurotoxicity that occurred at any time throughout the developmental process. In conclusion, while this investigation identified some critical exposure windows for motor development effects, it demonstrates a need for more acute duration exposure studies based on neurodevelopmental windows, particularly during the exposure periods identified in this review. PMID:26686904

Critical developmental windows for morphology and hematology revealed by intermittent and continuous hypoxic incubation in embryos of quail (Coturnix coturnix)

PubMed Central

Elmonoufy, Nourhan A.

2017-01-01

available. Collectively, these data indicate a critical developmental window for hypoxia susceptibility during the mid-embryonic period of development. PMID:28926567

Selection Process for New Windows | Efficient Windows Collaborative

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Foundry Foundry New Construction Windows Window Selection Tool Selection Process Design Guidance Installation Replacement Windows Window Selection Tool Assessing Options Selection Process Design Guidance Installation Understanding Windows Benefits Design Considerations Measuring Performance Performance Standards

Design Guidance for New Windows | Efficient Windows Collaborative

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Foundry Foundry New Construction Windows Window Selection Tool Selection Process Design Guidance Installation Replacement Windows Window Selection Tool Assessing Options Selection Process Design Guidance Installation Understanding Windows Benefits Design Considerations Measuring Performance Performance Standards

Selection Process for Replacement Windows | Efficient Windows Collaborative

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Foundry Foundry New Construction Windows Window Selection Tool Selection Process Design Guidance Installation Replacement Windows Window Selection Tool Assessing Options Selection Process Design Guidance Installation Understanding Windows Benefits Design Considerations Measuring Performance Performance Standards

Design Guidance for Replacement Windows | Efficient Windows Collaborative

Science.gov Websites

Foundry Foundry New Construction Windows Window Selection Tool Selection Process Design Guidance Installation Replacement Windows Window Selection Tool Assessing Options Selection Process Design Guidance Installation Understanding Windows Benefits Design Considerations Measuring Performance Performance Standards

Interferometer for Space Station Windows

NASA Technical Reports Server (NTRS)

Hall, Gregory

2003-01-01

Inspection of space station windows for micrometeorite damage would be a difficult task insitu using current inspection techniques. Commercially available optical profilometers and inspection systems are relatively large, about the size of a desktop computer tower, and require a stable platform to inspect the test object. Also, many devices currently available are designed for a laboratory or controlled environments requiring external computer control. This paper presents an approach using a highly developed optical interferometer to inspect the windows from inside the space station itself using a self- contained hand held device. The interferometer would be capable as a minimum of detecting damage as small as one ten thousands of an inch in diameter and depth while interrogating a relatively large area. The current developmental state of this device is still in the proof of concept stage. The background section of this paper will discuss the current state of the art of profilometers as well as the desired configuration of the self-contained, hand held device. Then, a discussion of the developments and findings that will allow the configuration change with suggested approaches appearing in the proof of concept section.

Tuning the emission of aqueous Cu:ZnSe quantum dots to yellow light window

NASA Astrophysics Data System (ADS)

Wang, Chunlei; Hu, Zhiyang; Xu, Shuhong; Wang, Yanbin; Zhao, Zengxia; Wang, Zhuyuan; Cui, Yiping

2015-07-01

Synthesis of internally doped Cu:ZnSe QDs in an aqueous solution still suffers from narrow tunable emissions from the blue to green light window. In this work, we extended the emission window of aqueous Cu:ZnSe QDs to the yellow light window. Our results show that high solution pH, multiple injections of Zn precursors, and nucleation doping strategy are three key factors for preparing yellow emitted Cu:ZnSe QDs. All these factors can depress the reactivity of CuSe nuclei and Zn monomers, promoting ZnSe growth outside CuSe nuclei rather than form ZnSe nuclei separately. With increased ZnSe QD size, the conduction band and nearby trap state energy levels shift to higher energy sites, causing Cu:ZnSe QDs to have a much longer emission.

Developmental milestones among Aboriginal children in Canada

PubMed Central

Findlay, Leanne; Kohen, Dafna; Miller, Anton

2014-01-01

BACKGROUND: Windows of achievement provide age ranges for the attainment of early developmental skills. Group-specific research is warranted given that development may be influenced by social or cultural factors. OBJECTIVES: To examine developmental milestones for Inuit, Métis and off-reserve First Nation children in Canada, based on developmental domains collected from the 2006 Aboriginal Children’s Survey. Sociodemographic and health predictors of risk for developmental delay were also examined. RESULTS: The ranges in which children achieve certain developmental milestones are presented. Gross motor and self-help skills were found to be achieved earlier (across the three Aboriginal groups), whereas language skills were achieved slightly later than in Canadian children in general. Furthermore, health factors (eg, low birth weight, chronic health conditions) were associated with late achievement of developmental outcomes even when sociodemographic characteristics were considered. CONCLUSIONS: Findings suggest that the timing of milestone achievement may differ for Aboriginal children, highlighting the importance of establishing culturally specific norms and standards rather than relying on those derived from general populations. This information may be useful for practitioners and parents interested in identifying the age ranges for development, as well as age ranges indicating potential for developmental risk and opportunities for early intervention among Aboriginal children. PMID:24855426

A narrow band pattern-matching model of vowel perception

NASA Astrophysics Data System (ADS)

Hillenbrand, James M.; Houde, Robert A.

2003-02-01

The purpose of this paper is to propose and evaluate a new model of vowel perception which assumes that vowel identity is recognized by a template-matching process involving the comparison of narrow band input spectra with a set of smoothed spectral-shape templates that are learned through ordinary exposure to speech. In the present simulation of this process, the input spectra are computed over a sufficiently long window to resolve individual harmonics of voiced speech. Prior to template creation and pattern matching, the narrow band spectra are amplitude equalized by a spectrum-level normalization process, and the information-bearing spectral peaks are enhanced by a ``flooring'' procedure that zeroes out spectral values below a threshold function consisting of a center-weighted running average of spectral amplitudes. Templates for each vowel category are created simply by averaging the narrow band spectra of like vowels spoken by a panel of talkers. In the present implementation, separate templates are used for men, women, and children. The pattern matching is implemented with a simple city-block distance measure given by the sum of the channel-by-channel differences between the narrow band input spectrum (level-equalized and floored) and each vowel template. Spectral movement is taken into account by computing the distance measure at several points throughout the course of the vowel. The input spectrum is assigned to the vowel template that results in the smallest difference accumulated over the sequence of spectral slices. The model was evaluated using a large database consisting of 12 vowels in /hVd/ context spoken by 45 men, 48 women, and 46 children. The narrow band model classified vowels in this database with a degree of accuracy (91.4%) approaching that of human listeners.

Window Operator Types | Efficient Windows Collaborative

Science.gov Websites

Types Casement Casement Casement windows are hinged at the sides. Hinged windows such as casements operating types to consider. Traditional operable window types include the projected or hinged types such as casement, awning, and hopper, and the sliding types such as double- and single-hung and horizontal sliding

How Does the Narrowing of Eligibility Criteria Affect Enrollment in Part C Early Intervention?

ERIC Educational Resources Information Center

Elbaum, Batya; Celimli-Aksoy, Seniz; Marshall, Jennifer T.; Berkovits, Michelle D.

2017-01-01

In recent years, many states have narrowed their eligibility criteria for participation in the IDEA Part C early intervention (EI) program for infants and toddlers with or at risk for developmental delays. However, there is scant research on the effects of such a policy change on the population of children served or on the timing of children's…

An Efficient Adaptive Window Size Selection Method for Improving Spectrogram Visualization.

PubMed

Nisar, Shibli; Khan, Omar Usman; Tariq, Muhammad

2016-01-01

Short Time Fourier Transform (STFT) is an important technique for the time-frequency analysis of a time varying signal. The basic approach behind it involves the application of a Fast Fourier Transform (FFT) to a signal multiplied with an appropriate window function with fixed resolution. The selection of an appropriate window size is difficult when no background information about the input signal is known. In this paper, a novel empirical model is proposed that adaptively adjusts the window size for a narrow band-signal using spectrum sensing technique. For wide-band signals, where a fixed time-frequency resolution is undesirable, the approach adapts the constant Q transform (CQT). Unlike the STFT, the CQT provides a varying time-frequency resolution. This results in a high spectral resolution at low frequencies and high temporal resolution at high frequencies. In this paper, a simple but effective switching framework is provided between both STFT and CQT. The proposed method also allows for the dynamic construction of a filter bank according to user-defined parameters. This helps in reducing redundant entries in the filter bank. Results obtained from the proposed method not only improve the spectrogram visualization but also reduce the computation cost and achieves 87.71% of the appropriate window length selection.

Developmental plasticity of growth and digestive efficiency in dependence of early-life food availability

PubMed Central

Kotrschal, Alexander; Szidat, Sönke; Taborsky, Barbara

2014-01-01

Nutrition is a potent mediator of developmental plasticity. If food is scarce, developing organisms may invest into growth to outgrow size-dependent mortality (short-term benefit) and/or into an efficient digestion system (long-term benefit). We investigated this potential trade-off, by determining the influence of food availability on juvenile body and organ growth, and on adult digestive efficiency in the cichlid fish Simochromis pleurospilus. We reared two groups of fish at constant high or low food rations, and we switched four other groups between these two rations at an early and late juvenile period. We measured juvenile growth and organ sizes at different developmental stages and determined adult digestive efficiency. Fish kept at constant, high rations grew considerably faster than low-food fish. Nevertheless, S. pleurospilus partly buffered the negative effects of low food availability by developing heavier digestive organs, and they were therefore more efficient in digesting their food as adults. Results of fish exposed to a ration switch during either the early or late juvenile period suggest (i) that the ability to show compensatory growth after early exposure to low food availability persists during the juvenile period, (ii) that digestive efficiency is influenced by varying juvenile food availability during the late juvenile phase and (iii) that the efficiency of the adult digestive system is correlated with the growth rate during a narrow time window of juvenile period. PMID:25866430

Diversity & Developmentally Appropriate Practices: Challenges for Early Childhood Education.

ERIC Educational Resources Information Center

Mallory, Bruce L., Ed.; New, Rebecca S., Ed.

The current conceptualization of what is appropriate in early childhood education is overly narrow in its interpretation of the role of the teacher, and with respect to variations in cultural and developmental diversity. Based on this observation, this book discusses various issues surrounding diversity, inclusion, and appropriate early…

BE-PLUS: a new base editing tool with broadened editing window and enhanced fidelity.

PubMed

Jiang, Wen; Feng, Songjie; Huang, Shisheng; Yu, Wenxia; Li, Guanglei; Yang, Guang; Liu, Yajing; Zhang, Yu; Zhang, Lei; Hou, Yu; Chen, Jia; Chen, Jieping; Huang, Xingxu

2018-06-06

Base editor (BE), containing a cytidine deaminase and catalytically defective Cas9, has been widely used to perform base editing. However, the narrow editing window of BE limits its utility. Here, we developed a new editing technology named as base editor for programming larger C to U (T) scope (BE-PLUS) by fusing 10 copies of GCN4 peptide to nCas9(D10A) for recruiting scFv-APOBEC-UGI-GB1 to the target sites. The new system achieves base editing with a broadened window, resulting in an increased genome-targeting scope. Interestingly, the new system yielded much fewer unwanted indels and non-C-to-T conversions. We also demonstrated its potential use in gene disruption across the whole genome through induction of stop codons (iSTOP). Taken together, the BE-PLUS system offers a new editing tool with increased editing window and enhanced fidelity.

Strategies for Reversing the Effects of Metabolic Disorders Induced as a Consequence of Developmental Programming

PubMed Central

Vickers, M. H.; Sloboda, D. M.

2012-01-01

Obesity and the metabolic syndrome have reached epidemic proportions worldwide with far-reaching health care and economic implications. The rapid increase in the prevalence of these disorders suggests that environmental and behavioral influences, rather than genetic causes, are fueling the epidemic. The developmental origins of health and disease hypothesis has highlighted the link between the periconceptual, fetal, and early infant phases of life and the subsequent development of metabolic disorders in later life. In particular, the impact of poor maternal nutrition on susceptibility to later life metabolic disease in offspring is now well documented. Several studies have now shown, at least in experimental animal models, that some components of the metabolic syndrome, induced as a consequence of developmental programming, are potentially reversible by nutritional or targeted therapeutic interventions during windows of developmental plasticity. This review will focus on critical windows of development and possible therapeutic avenues that may reduce metabolic and obesogenic risk following an adverse early life environment. PMID:22783205

Laser window with annular grooves for thermal isolation

DOEpatents

Warner, B.E.; Horton, J.A.; Alger, T.W.

1983-07-13

A laser window or other optical element which is thermally loaded, heats up and causes optical distortions because of temperature gradients between the center and the edge. A number of annular grooves, one to three or more, are formed in the element between a central portion and edge portion, producing a web portion which concentrates the thermal gradient and thermally isolates the central portion from the edge portion, producing a uniform temperature profile across the central portion and therefore reduce the optical distortions. The grooves are narrow and closely spaced with respect to the thickness of the element, and successive grooves are formed from alternate sides of the element.

Bayesian distributed lag interaction models to identify perinatal windows of vulnerability in children's health.

PubMed

Wilson, Ander; Chiu, Yueh-Hsiu Mathilda; Hsu, Hsiao-Hsien Leon; Wright, Robert O; Wright, Rosalind J; Coull, Brent A

2017-07-01

Epidemiological research supports an association between maternal exposure to air pollution during pregnancy and adverse children's health outcomes. Advances in exposure assessment and statistics allow for estimation of both critical windows of vulnerability and exposure effect heterogeneity. Simultaneous estimation of windows of vulnerability and effect heterogeneity can be accomplished by fitting a distributed lag model (DLM) stratified by subgroup. However, this can provide an incomplete picture of how effects vary across subgroups because it does not allow for subgroups to have the same window but different within-window effects or to have different windows but the same within-window effect. Because the timing of some developmental processes are common across subpopulations of infants while for others the timing differs across subgroups, both scenarios are important to consider when evaluating health risks of prenatal exposures. We propose a new approach that partitions the DLM into a constrained functional predictor that estimates windows of vulnerability and a scalar effect representing the within-window effect directly. The proposed method allows for heterogeneity in only the window, only the within-window effect, or both. In a simulation study we show that a model assuming a shared component across groups results in lower bias and mean squared error for the estimated windows and effects when that component is in fact constant across groups. We apply the proposed method to estimate windows of vulnerability in the association between prenatal exposures to fine particulate matter and each of birth weight and asthma incidence, and estimate how these associations vary by sex and maternal obesity status in a Boston-area prospective pre-birth cohort study. © The Author 2017. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Linewidth narrowing for 31Phosphorus MRI of cell membranes

NASA Astrophysics Data System (ADS)

Barrett, Sean; Frey, Merideth; Madri, Joseph; Michaud, Michael

2011-03-01

Most 31 P Magnetic Resonance Spectroscopy studies of tissues try to avoid contamination by a relatively large, but broad, spectral feature attributed to cell membrane phospholipids. MRI using this broad 31 P membrane spectrum is not even attempted, since the spatial resolution and signal-to-noise would be poor, relative to conventional MRI using the narrow 1 H water spectrum. This long-standing barrier has been overcome by a novel pulse sequence, recently discovered in fundamental quantum computation research, which narrows the broad 31 P spectrum by ~ 1000 × . Applying time-dependent gradients in synch with a repeating pulse block enables a new route to high spatial resolution, 3D 31 P MRI of the soft solid components of cells and tissues. So far, intact and sectioned samples of ex vivo fixed mouse organs have been imaged, with (sub-mm)3 voxels. Extending the reach of MRI to broad spectra in natural and artificial tissues opens a new window into cells, enabling progress in biomedical research. W.J. Thoma et al., J. MR 61, 141 (1985); E.J. Murphy et al., MR Med 12, 282 (1989); R. McNamara et al., NMR Biomed 7, 237 (1994).

Replacement Windows for Existing Homes Homes | Efficient Windows

Science.gov Websites

Design Guidance Installation Replacement Windows Window Selection Tool Assessing Options Selection Process Design Guidance Installation Understanding Windows Benefits Design Considerations Measuring Selection Tool will take you through a series of design conditions pertaining to your design and location

REPRODUCTIVE AND DEVELOPMENTAL EFFECTS OF CONTAMINANTS IN OVIPAROUS VERTEBRATES: WORKSHOP SUMMARY, CONCLUSIONS, AND RECOMMENDATIONS

EPA Science Inventory

Oviparous vertebrates generally occupy important niches in aquatic as well as terrestrial systems, and reproductive and developmental effects on these species can be of relatively great ecological significance. Because these organisms have critical windows of development, they ma...

Development of a Novel Floating In-situ Gelling System for Stomach Specific Drug Delivery of the Narrow Absorption Window Drug Baclofen.

PubMed

R Jivani, Rishad; N Patel, Chhagan; M Patel, Dashrath; P Jivani, Nurudin

2010-01-01

The present study deals with development of a floating in-situ gel of the narrow absorption window drug baclofen. Sodium alginate-based in-situ gelling systems were prepared by dissolving various concentrations of sodium alginate in deionized water, to which varying concentrations of drug and calcium bicarbonate were added. Fourier transform infrared spectroscopy (FTIR) and differential scanning calorimetry (DSC) were used to check the presence of any interaction between the drug and the excipients. A 3(2) full factorial design was used for optimization. The concentrations of sodium alginate (X1) and calcium bicarbonate (X2) were selected as the independent variables. The amount of the drug released after 1 h (Q1) and 10 h (Q10) and the viscosity of the solution were selected as the dependent variables. The gels were studied for their viscosity, in-vitro buoyancy and drug release. Contour plots were drawn for each dependent variable and check-point batches were prepared in order to get desirable release profiles. The drug release profiles were fitted into different kinetic models. The floating lag time and floating time found to be 2 min and 12 h respectively. A decreasing trend in drug release was observed with increasing concentrations of CaCO3. The computed values of Q1 and Q10 for the check-point batch were 25% and 86% respectively, compared to the experimental values of 27.1% and 88.34%. The similarity factor (f 2) for the check-point batch being 80.25 showed that the two dissolution profiles were similar. The drug release from the in-situ gel follows the Higuchi model, which indicates a diffusion-controlled release. A stomach specific in-situ gel of baclofen could be prepared using floating mechanism to increase the residence time of the drug in stomach and thereby increase the absorption.

Design, Fabrication and Testing of Multilayer Coated X-Ray Optics for the Water Window Imaging X-Ray Microscope

NASA Technical Reports Server (NTRS)

Spencer, Dwight C.

1996-01-01

Hoover et. al. built and tested two imaging Schwarzschild multilayer microscopes. These instruments were constructed as prototypes for the "Water Window Imaging X-Ray Microscope," which is a doubly reflecting, multilayer x-ray microscope configured to operate within the "water window." The "water window" is the narrow region of the x-ray spectrum between the K absorption edges of oxygen (lamda = 23.3 Angstroms) and of carbon (lamda = 43.62 Angstroms), where water is relatively highly transmissive and carbon is highly absorptive. This property of these materials, thus permits the use of high resolution multilayer x-ray microscopes for producing high contrast images of carbon-based structures within the aqueous physiological environments of living cells. We report the design, fabrication and testing of multilayer optics that operate in this regime.

Brief daily exposures to Asian females reverses perceptual narrowing for Asian faces in Caucasian infants

PubMed Central

Anzures, Gizelle; Wheeler, Andrea; Quinn, Paul C.; Pascalis, Olivier; Slater, Alan M.; Heron-Delaney, Michelle; Tanaka, James W.; Lee, Kang

2012-01-01

Perceptual narrowing in the visual, auditory, and multisensory domains has its developmental origins in infancy. The present study shows that experimentally induced experience can reverse the effects of perceptual narrowing on infants’ visual recognition memory of other-race faces. Caucasian 8- to 10-month-olds who could not discriminate between novel and familiarized Asian faces at the beginning of testing were given brief daily experience with Asian female faces in the experimental condition and Caucasian female faces in the control condition. At the end of three weeks, only infants who received daily experience with Asian females showed above-chance recognition of novel Asian female and male faces. Further, infants in the experimental condition showed greater efficiency in learning novel Asian females compared to infants in the control condition. Thus, visual experience with a novel stimulus category can reverse the effects of perceptual narrowing in infancy via improved stimulus recognition and encoding. PMID:22625845

From Mice to Men: research models of developmental programming

PubMed Central

Rabadán-Diehl, C.; Nathanielsz, P.

2012-01-01

Developmental programming can be defined as a response to a specific challenge to the mammalian organism during a critical developmental time window that alters the trajectory of development with persistent effects on offspring phenotype and predisposition to future illness. We focus on the need for studies in relevant, well-characterized animal models in the context of recent research discoveries on the challenges, mechanisms and outcomes of developmental programming. We discuss commonalities and differences in general principles of developmental programming as they apply to several species, including humans. The consequences of these differences are discussed. Obesity, metabolic disorders and cardiovascular diseases are associated with the highest percentage of morbidity and mortality worldwide. Although many of the causes are associated with lifestyle, high-energy diets and lack of physical activity, recent evidence has linked developmental programming to the epidemic of metabolic diseases. A better understanding of comparative systems physiology of mother, fetus and neonate using information provided by rapid advances in molecular biology has the potential to improve the lifetime health of future generations by providing better women’s health, diagnostic tools and preventative and therapeutic interventions in individuals exposed during their development to programming influences. PMID:23525085

The Traditional Approach to Developmental Education: Background and Effectiveness. Research Brief

ERIC Educational Resources Information Center

Horn, Aaron S.; Asmussen, John G.

2014-01-01

A significant challenge in higher education is to narrow the educational attainment gap between academically prepared and unprepared students. To this end, developmental or remedial education is intended to improve the academic skills and knowledge of students who are unprepared for undergraduate coursework, particularly in the areas of…

Interactions between Auxin Transport and the Actin Cytoskeleton in Developmental Polarity of Fucus distichus Embryos in Response to Light and Gravity1

PubMed Central

Sun, Haiguo; Basu, Swati; Brady, Shari R.; Luciano, Randy L.; Muday, Gloria K.

2004-01-01

Land plants orient their growth relative to light and gravity through complex mechanisms that require auxin redistribution. Embryos of brown algae use similar environmental stimuli to orient their developmental polarity. These studies of the brown algae Fucus distichus examined whether auxin and auxin transport are also required during polarization in early embryos and to orient growth in already developed tissues. These embryos polarize with the gravity vector in the absence of a light cue. The auxin, indole-3-acetic acid (IAA), and auxin efflux inhibitors, such as naphthylphthalamic acid (NPA), reduced environmental polarization in response to gravity and light vectors. Young rhizoids are negatively phototropic, and NPA also inhibits rhizoid phototropism. The effect of IAA and NPA on gravity and photopolarization is maximal within 2.5 to 4.5 h after fertilization (AF). Over the first 6 h AF, auxin transport is relatively constant, suggesting that developmentally controlled sensitivity to auxin determines the narrow window during which NPA and IAA reduce environmental polarization. Actin patches were formed during the first hour AF and began to photolocalize within 3 h, coinciding with the time of NPA and IAA action. Treatment with NPA reduced the polar localization of actin patches but not patch formation. Latrunculin B prevented environmental polarization in a time frame that overlaps the formation of actin patches and IAA and NPA action. Latrunculin B also altered auxin transport. Together, these results indicate a role for auxin in the orientation of developmental polarity and suggest interactions between the actin cytoskeleton and auxin transport in F. distichus embryos. PMID:15122028

Cortical Development, Plasticity and Re-Organization in Children with Cochlear Implants

ERIC Educational Resources Information Center

Sharma, Anu; Nash, Amy A.; Dorman, Michael

2009-01-01

A basic tenet of developmental neurobiology is that certain areas of the cortex will re-organize, if appropriate stimulation is withheld for long periods. Stimulation must be delivered to a sensory system within a narrow window of time (a sensitive period) if that system is to develop normally. In this article, we will describe age cut-offs for a…

Mindfulness and Compassion Training in Adolescence: A Developmental Contemplative Science Perspective

ERIC Educational Resources Information Center

Roeser, Robert W.; Pinela, Cristi

2014-01-01

Adolescence is a developmental period of risk, as well as a window of opportunity for cultivating positive development and thriving. It is characterized by simultaneous changes in the brain, body, mind, and social domains that offer a platform for building new skills and habits. This chapter discusses the role that secular forms of mindfulness and…

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On the relationship between instantaneous phase synchrony and correlation-based sliding windows for time-resolved fMRI connectivity analysis.

PubMed

Pedersen, Mangor; Omidvarnia, Amir; Zalesky, Andrew; Jackson, Graeme D

2018-06-08

Correlation-based sliding window analysis (CSWA) is the most commonly used method to estimate time-resolved functional MRI (fMRI) connectivity. However, instantaneous phase synchrony analysis (IPSA) is gaining popularity mainly because it offers single time-point resolution of time-resolved fMRI connectivity. We aim to provide a systematic comparison between these two approaches, on both temporal and topological levels. For this purpose, we used resting-state fMRI data from two separate cohorts with different temporal resolutions (45 healthy subjects from Human Connectome Project fMRI data with repetition time of 0.72 s and 25 healthy subjects from a separate validation fMRI dataset with a repetition time of 3 s). For time-resolved functional connectivity analysis, we calculated tapered CSWA over a wide range of different window lengths that were temporally and topologically compared to IPSA. We found a strong association in connectivity dynamics between IPSA and CSWA when considering the absolute values of CSWA. The association between CSWA and IPSA was stronger for a window length of ∼20 s (shorter than filtered fMRI wavelength) than ∼100 s (longer than filtered fMRI wavelength), irrespective of the sampling rate of the underlying fMRI data. Narrow-band filtering of fMRI data (0.03-0.07 Hz) yielded a stronger relationship between IPSA and CSWA than wider-band (0.01-0.1 Hz). On a topological level, time-averaged IPSA and CSWA nodes were non-linearly correlated for both short (∼20 s) and long (∼100 s) windows, mainly because nodes with strong negative correlations (CSWA) displayed high phase synchrony (IPSA). IPSA and CSWA were anatomically similar in the default mode network, sensory cortex, insula and cerebellum. Our results suggest that IPSA and CSWA provide comparable characterizations of time-resolved fMRI connectivity for appropriately chosen window lengths. Although IPSA requires narrow-band fMRI filtering, we recommend the use of

Window treatments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nielson, K.J.

1990-01-01

This book includes basic material as well as information the professional needs for designing appropriate window treatments for residential and nonresidential buildings: site, orientation, climate, energy efficiency, sound-proofing, privacy, protection, view, ventilation and interior and exterior aesthetics. Also includes a guide to the window treatment industry, a list of manufacturers, distributors, and retailers, information on window treatment fibers and fabrics, three glossaries, an extensive bibliography, and over 800 illustrations.

Through Shared Windows: Outreach Project for Infants, Toddlers, and Children with Developmental Disabilities. Final Report.

ERIC Educational Resources Information Center

Harrison, Holly

This final report describes activities and accomplishments of the Through Shared Windows (TSW) Outreach Project, a 4-year project at the University of New Mexico designed to improve services to young children with disabilities and their families. Three major outcomes were accomplished. First, a Web site was developed that focuses on observational…

The Construct of the Multisensory Temporal Binding Window and its Dysregulation in Developmental Disabilities

PubMed Central

Wallace, Mark T.; Stevenson, Ryan A.

2014-01-01

Behavior, perception and cognition are strongly shaped by the synthesis of information across the different sensory modalities. Such multisensory integration often results in performance and perceptual benefits that reflect the additional information conferred by having cues from multiple senses providing redundant or complementary information. The spatial and temporal relationships of these cues provide powerful statistical information about how these cues should be integrated or “bound” in order to create a unified perceptual representation. Much recent work has examined the temporal factors that are integral in multisensory processing, with many focused on the construct of the multisensory temporal binding window – the epoch of time within which stimuli from different modalities is likely to be integrated and perceptually bound. Emerging evidence suggests that this temporal window is altered in a series of neurodevelopmental disorders, including autism, dyslexia and schizophrenia. In addition to their role in sensory processing, these deficits in multisensory temporal function may play an important role in the perceptual and cognitive weaknesses that characterize these clinical disorders. Within this context, focus on improving the acuity of multisensory temporal function may have important implications for the amelioration of the “higher-order” deficits that serve as the defining features of these disorders. PMID:25128432

Wide electrochemical window of supercapacitors from coffee bean-derived phosphorus-rich carbons.

PubMed

Huang, Congcong; Sun, Ting; Hulicova-Jurcakova, Denisa

2013-12-01

Phosphorus-rich carbons (PCs) were prepared by phosphoric acid activation of waste coffee grounds in different impregnation ratios. PCs were characterized by nitrogen and carbon dioxide adsorption and X-ray photoelectron spectroscopy. The results indicate that the activation step not only creates a porous structure, but also introduces various phosphorus and oxygen functional groups to the surface of carbons. As evidenced by cyclic voltammetry, galvanostatic charge/discharge, and wide potential window tests, a supercapacitor constructed from PC-2 (impregnation ratio of 2), with the highest phosphorus content, can operate very stably in 1 M H2 SO4 at 1.5 V with only 18 % degradation after 10 000 cycles at a current density of 5 A g(-1) . Due to the wide electrochemical window, a supercapacitor assembled with PC-2 has a high energy density of 15 Wh kg(-1) at a power density of 75 W kg(-1) . The possibility of widening the potential window above the theoretical potential for the decomposition of water is attributed to reversible electrochemical hydrogen storage in narrow micropores and the positive effect of phosphorus-rich functional groups, particularly the polyphosphates on the carbon surface. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

The monaural temporal window based on masking period pattern data in school-aged children and adults.

PubMed

Buss, Emily; He, Shuman; Grose, John H; Hall, Joseph W

2013-03-01

Several lines of evidence indicate that auditory temporal resolution improves over childhood, whereas other data implicate the development of processing efficiency. The present study used the masking period pattern paradigm to examine the maturation of temporal processing in normal-hearing children (4.8 to 10.7 yrs) compared to adults. Thresholds for a brief tone were measured at 6 temporal positions relative to the period of a 5-Hz quasi-square-wave masker envelope, with a 20-dB modulation depth, as well as in 2 steady maskers. The signal was a pure tone at either 1000 or 6500 Hz, and the masker was a band of noise, either spectrally wide or narrow (21.3 and 1.4 equivalent rectangular bandwidths, respectively). Masker modulation improved thresholds more for wide than narrow bandwidths, and adults tended to receive more benefit from modulation than young children. Fits to data for the wide maskers indicated a change in window symmetry with development, reflecting relatively greater backward masking for the youngest listeners. Data for children >6.5 yrs of age appeared more adult-like for the 6500- than the 1000-Hz signal. Differences in temporal window asymmetry with listener age cannot be entirely explained as a consequence of a higher criterion for detection in children, a form of inefficiency.

DPOAEs in infants developmentally exposed to PCBs show two differently time spaced exposure sensitive windows.

PubMed

Koštiaková, Vladimíra; Moleti, Arturo; Wimmerová, Soňa; Jusko, Todd A; Palkovičová Murínová, Ľubica; Sisto, Renata; Richterová, Denisa; Kováč, Ján; Čonka, Kamil; Patayová, Henrieta; Tihányi, Juraj; Trnovec, Tomáš

2016-10-01

The study aim was to identify the timing of sensitive windows for ototoxicity related to perinatal exposure to PCBs. A total of 351 and 214 children from a birth cohort in eastern Slovakia underwent otoacoustic testing at 45 and 72 months, respectively, and distortion product otoacoustic emissions (DPOAEs) at 11 frequencies were recorded. Cord and child 6-, 16-, 45-, and 72- month blood samples were analyzed for PCB 153 concentration. The PCB 153 concentration-time profiles were approximated with a system model to calculate area under the PCB*time curves (AUCs) for specific time intervals (3 and 6 months for 45 and 72 months data, respectively). DPOAE amplitudes were correlated (Spearman) with cord serum PCB and AUCs, markers of prenatal and postnatal exposure, respectively. Two exposure critical windows were identified in infants, the first related to prenatal and early postnatal and the second to postnatal exposure to PCBs. Our data have shown tonotopicity, sexual dimorphism, and asymmetry in ototoxicity of PCBs. Copyright © 2016. Published by Elsevier Ltd.

Inside storm window

NASA Astrophysics Data System (ADS)

Kaplan, J. I.

1980-11-01

The work effort to design, build, install, and evaluate an inside storm window (ISW) is presented. The ISW, made of two separated layers of mylar (like a thermopane window) which, when not in use can be rolled up in a shade, is described. The work effort included: development of a prototype model; the development of production facilities to turn out a small number (50) of ISW's; the production of the windows; the installation of the windows into buildings; the building of a test chamber to determine the R value of the ISW and the subsequent determination of the R value; and a survey to determine how the residents of the homes in which ISW's were installed felt about the windows.

Efficient Windows Collaborative

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nils Petermann

2010-02-28

The project goals covered both the residential and commercial windows markets and involved a range of audiences such as window manufacturers, builders, homeowners, design professionals, utilities, and public agencies. Essential goals included: (1) Creation of 'Master Toolkits' of information that integrate diverse tools, rating systems, and incentive programs, customized for key audiences such as window manufacturers, design professionals, and utility programs. (2) Delivery of education and outreach programs to multiple audiences through conference presentations, publication of articles for builders and other industry professionals, and targeted dissemination of efficient window curricula to professionals and students. (3) Design and implementation of mechanismsmore » to encourage and track sales of more efficient products through the existing Window Products Database as an incentive for manufacturers to improve products and participate in programs such as NFRC and ENERGY STAR. (4) Development of utility incentive programs to promote more efficient residential and commercial windows. Partnership with regional and local entities on the development of programs and customized information to move the market toward the highest performing products. An overarching project goal was to ensure that different audiences adopt and use the developed information, design and promotion tools and thus increase the market penetration of energy efficient fenestration products. In particular, a crucial success criterion was to move gas and electric utilities to increase the promotion of energy efficient windows through demand side management programs as an important step toward increasing the market share of energy efficient windows.« less

Do convergent developmental mechanisms underlie convergent phenotypes?

NASA Technical Reports Server (NTRS)

Wray, Gregory A.

2002-01-01

Convergence is a pervasive evolutionary process, affecting many aspects of phenotype and even genotype. Relatively little is known about convergence in developmental processes, however, nor about the degree to which convergence in development underlies convergence in anatomy. A switch in the ecology of sea urchins from feeding to nonfeeding larvae illustrates how convergence in development can be associated with convergence in anatomy. Comparisons to more distantly related taxa, however, suggest that this association may be limited to relatively close phylogenetic comparisons. Similarities in gene expression during development provide another window into the association between convergence in developmental processes and convergence in anatomy. Several well-studied transcription factors exhibit likely cases of convergent gene expression in distantly related animal phyla. Convergence in regulatory gene expression domains is probably more common than generally acknowledged, and can arise for several different reasons. Copyright 2002 S. Karger AG, Basel.

Proper Installation of New Windows | Efficient Windows Collaborative

Science.gov Websites

airtight fit and avoid water leakage. Always follow manufacturers installation guidelines and use trained professionals for window installation. Proper installation will: Protect from water damage. Windows should form a continuous water barrier where they meet the wall. With improper installation, water may penetrate

Is Perceptual Narrowing Too Narrow?

ERIC Educational Resources Information Center

Cashon, Cara H.; Denicola, Christopher A.

2011-01-01

There is a growing list of examples illustrating that infants are transitioning from having earlier abilities that appear more "universal," "broadly tuned," or "unconstrained" to having later abilities that appear more "specialized," "narrowly tuned," or "constrained." Perceptual narrowing, a well-known phenomenon related to face, speech, and…

Ube3a reinstatement identifies distinct developmental windows in a murine Angelman syndrome model

PubMed Central

Silva-Santos, Sara; van Woerden, Geeske M.; Bruinsma, Caroline F.; Mientjes, Edwin; Jolfaei, Mehrnoush Aghadavoud; Distel, Ben; Kushner, Steven A.; Elgersma, Ype

2015-01-01

Angelman syndrome (AS) is a severe neurodevelopmental disorder that results from loss of function of the maternal ubiquitin protein ligase E3A (UBE3A) allele. Due to neuron-specific imprinting, the paternal UBE3A copy is silenced. Previous studies in murine models have demonstrated that strategies to activate the paternal Ube3a allele are feasible; however, a recent study showed that pharmacological Ube3a gene reactivation in adulthood failed to rescue the majority of neurocognitive phenotypes in a murine AS model. Here, we performed a systematic study to investigate the possibility that neurocognitive rescue can be achieved by reinstating Ube3a during earlier neurodevelopmental windows. We developed an AS model that allows for temporally controlled Cre-dependent induction of the maternal Ube3a allele and determined that there are distinct neurodevelopmental windows during which Ube3a restoration can rescue AS-relevant phenotypes. Motor deficits were rescued by Ube3a reinstatement in adolescent mice, whereas anxiety, repetitive behavior, and epilepsy were only rescued when Ube3a was reinstated during early development. In contrast, hippocampal synaptic plasticity could be restored at any age. Together, these findings suggest that Ube3a reinstatement early in development may be necessary to prevent or rescue most AS-associated phenotypes and should be considered in future clinical trial design. PMID:25866966

Critical disease windows shaped by stress exposure alter allocation trade-offs between development and immunity.

PubMed

Kirschman, Lucas J; Crespi, Erica J; Warne, Robin W

2018-01-01

Ubiquitous environmental stressors are often thought to alter animal susceptibility to pathogens and contribute to disease emergence. However, duration of exposure to a stressor is likely critical, because while chronic stress is often immunosuppressive, acute stress can temporarily enhance immune function. Furthermore, host susceptibility to stress and disease often varies with ontogeny; increasing during critical developmental windows. How the duration and timing of exposure to stressors interact to shape critical windows and influence disease processes is not well tested. We used ranavirus and larval amphibians as a model system to investigate how physiological stress and pathogenic infection shape development and disease dynamics in vertebrates. Based on a resource allocation model, we designed experiments to test how exposure to stressors may induce resource trade-offs that shape critical windows and disease processes because the neuroendocrine stress axis coordinates developmental remodelling, immune function and energy allocation in larval amphibians. We used wood frog larvae (Lithobates sylvaticus) to investigate how chronic and acute exposure to corticosterone, the dominant amphibian glucocorticoid hormone, mediates development and immune function via splenocyte immunohistochemistry analysis in association with ranavirus infection. Corticosterone treatments affected immune function, as both chronic and acute exposure suppressed splenocyte proliferation, although viral replication rate increased only in the chronic corticosterone treatment. Time to metamorphosis and survival depended on both corticosterone treatment and infection status. In the control and chronic corticosterone treatments, ranavirus infection decreased survival and delayed metamorphosis, although chronic corticosterone exposure accelerated rate of metamorphosis in uninfected larvae. Acute corticosterone exposure accelerated metamorphosis increased survival in infected larvae. Interactions

Design Considerations | Efficient Windows Collaborative

Science.gov Websites

Foundry Foundry New Construction Windows Window Selection Tool Selection Process Design Guidance Installation Replacement Windows Window Selection Tool Assessing Options Selection Process Design Guidance Installation Understanding Windows Benefits Design Considerations Measuring Performance Performance Standards

Gas Fills | Efficient Windows Collaborative

Science.gov Websites

Foundry Foundry New Construction Windows Window Selection Tool Selection Process Design Guidance Installation Replacement Windows Window Selection Tool Assessing Options Selection Process Design Guidance Installation Understanding Windows Benefits Design Considerations Measuring Performance Performance Standards

Books & Publications | Efficient Windows Collaborative

Science.gov Websites

Foundry Foundry New Construction Windows Window Selection Tool Selection Process Design Guidance Installation Replacement Windows Window Selection Tool Assessing Options Selection Process Design Guidance Installation Understanding Windows Benefits Design Considerations Measuring Performance Performance Standards

Provide Views | Efficient Windows Collaborative

Science.gov Websites

Foundry Foundry New Construction Windows Window Selection Tool Selection Process Design Guidance Installation Replacement Windows Window Selection Tool Assessing Options Selection Process Design Guidance Installation Understanding Windows Benefits Design Considerations Measuring Performance Performance Standards

Reducing Condensation | Efficient Windows Collaborative

Science.gov Websites

Foundry Foundry New Construction Windows Window Selection Tool Selection Process Design Guidance Installation Replacement Windows Window Selection Tool Assessing Options Selection Process Design Guidance Installation Understanding Windows Benefits Design Considerations Measuring Performance Performance Standards

Reduced Fading | Efficient Windows Collaborative

Science.gov Websites

Foundry Foundry New Construction Windows Window Selection Tool Selection Process Design Guidance Installation Replacement Windows Window Selection Tool Assessing Options Selection Process Design Guidance Installation Understanding Windows Benefits Design Considerations Measuring Performance Performance Standards

EWC Membership | Efficient Windows Collaborative

Science.gov Websites

Foundry Foundry New Construction Windows Window Selection Tool Selection Process Design Guidance Installation Replacement Windows Window Selection Tool Assessing Options Selection Process Design Guidance Installation Understanding Windows Benefits Design Considerations Measuring Performance Performance Standards

Visible Transmittance | Efficient Windows Collaborative

Science.gov Websites

Foundry Foundry New Construction Windows Window Selection Tool Selection Process Design Guidance Installation Replacement Windows Window Selection Tool Assessing Options Selection Process Design Guidance Installation Understanding Windows Benefits Design Considerations Measuring Performance Performance Standards

EWC Members | Efficient Windows Collaborative

Science.gov Websites

Foundry Foundry New Construction Windows Window Selection Tool Selection Process Design Guidance Installation Replacement Windows Window Selection Tool Assessing Options Selection Process Design Guidance Installation Understanding Windows Benefits Design Considerations Measuring Performance Performance Standards

Financing & Incentives | Efficient Windows Collaborative

Science.gov Websites

Foundry Foundry New Construction Windows Window Selection Tool Selection Process Design Guidance Installation Replacement Windows Window Selection Tool Assessing Options Selection Process Design Guidance Installation Understanding Windows Benefits Design Considerations Measuring Performance Performance Standards

Letter-sound processing deficits in children with developmental dyslexia: An ERP study.

PubMed

Moll, Kristina; Hasko, Sandra; Groth, Katharina; Bartling, Jürgen; Schulte-Körne, Gerd

2016-04-01

The time course during letter-sound processing was investigated in children with developmental dyslexia (DD) and typically developing (TD) children using electroencephalography. Thirty-eight children with DD and 25 TD children participated in a visual-auditory oddball paradigm. Event-related potentials (ERPs) elicited by standard and deviant stimuli in an early (100-190 ms) and late (560-750 ms) time window were analysed. In the early time window, ERPs elicited by the deviant stimulus were delayed and less left lateralized over fronto-temporal electrodes for children with DD compared to TD children. In the late time window, children with DD showed higher amplitudes extending more over right frontal electrodes. Longer latencies in the early time window and stronger right hemispheric activation in the late time window were associated with slower reading and naming speed. Additionally, stronger right hemispheric activation in the late time window correlated with poorer phonological awareness skills. Deficits in early stages of letter-sound processing influence later more explicit cognitive processes during letter-sound processing. Identifying the neurophysiological correlates of letter-sound processing and their relation to reading related skills provides insight into the degree of automaticity during letter-sound processing beyond behavioural measures of letter-sound-knowledge. Copyright © 2016 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

details: window jamb from first period of construction; window jamb, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

details: window jamb from first period of construction; window jamb, sill profile, and transom profile from second period of construction - Joseph Poffenberger Farm, House, 17834 Mansfield Avenue, Sharpsburg, Washington County, MD

CAVE WINDOW

DOEpatents

Levenson, M.

1960-10-25

A cave window is described. It is constructed of thick glass panes arranged so that interior panes have smaller windowpane areas and exterior panes have larger areas. Exterior panes on the radiation exposure side are remotely replaceable when darkened excessively. Metal shutters minimize exposure time to extend window life.

Air transparent soundproof window

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, Sang-Hoon, E-mail: shkim@mmu.ac.kr; Lee, Seong-Hyun

2014-11-15

A soundproof window or wall which is transparent to airflow is presented. The design is based on two wave theories: the theory of diffraction and the theory of acoustic metamaterials. It consists of a three-dimensional array of strong diffraction-type resonators with many holes centered on each individual resonator. The negative effective bulk modulus of the resonators produces evanescent wave, and at the same time the air holes with subwavelength diameter existed on the surfaces of the window for macroscopic air ventilation. The acoustic performance levels of two soundproof windows with air holes of 20mm and 50mm diameters were measured. Themore » sound level was reduced by about 30 - 35dB in the frequency range of 400 - 5,000Hz with the 20mm window, and by about 20 - 35dB in the frequency range of 700 - 2,200Hz with the 50mm window. Multi stop-band was created by the multi-layers of the window. The attenuation length or the thickness of the window was limited by background noise. The effectiveness of the soundproof window with airflow was demonstrated by a real installation.« less

Sunlight Responsive Thermochromic Window System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Millett, F,A; Byker,H, J

2006-10-27

Pleotint has embarked on a novel approach with our Sunlight Responsive Thermochromic, SRT™, windows. We are integrating dynamic sunlight control, high insulation values and low solar heat gain together in a high performance window. The Pleotint SRT window is dynamic because it reversibly changes light transmission based on thermochromics activated directly by the heating effect of sunlight. We can achieve a window package with low solar heat gain coefficient (SHGC), a low U value and high insulation. At the same time our windows provide good daylighting. Our innovative window design offers architects and building designers the opportunity to choose theirmore » desired energy performance, excellent sound reduction, external pane can be self-cleaning, or a resistance to wind load, blasts, bullets or hurricanes. SRT windows would provide energy savings that are estimated at up to 30% over traditional window systems. Glass fabricators will be able to use existing equipment to make the SRT window while adding value and flexibility to the basic design. Glazing installers will have the ability to fit the windows with traditional methods without wires, power supplies and controllers. SRT windows can be retrofit into existing buildings,« less

Developmental Changes in Organization of Structural Brain Networks

PubMed Central

Khundrakpam, Budhachandra S.; Reid, Andrew; Brauer, Jens; Carbonell, Felix; Lewis, John; Ameis, Stephanie; Karama, Sherif; Lee, Junki; Chen, Zhang; Das, Samir; Evans, Alan C.; Ball, William S.; Byars, Anna Weber; Schapiro, Mark; Bommer, Wendy; Carr, April; German, April; Dunn, Scott; Rivkin, Michael J.; Waber, Deborah; Mulkern, Robert; Vajapeyam, Sridhar; Chiverton, Abigail; Davis, Peter; Koo, Julie; Marmor, Jacki; Mrakotsky, Christine; Robertson, Richard; McAnulty, Gloria; Brandt, Michael E.; Fletcher, Jack M.; Kramer, Larry A.; Yang, Grace; McCormack, Cara; Hebert, Kathleen M.; Volero, Hilda; Botteron, Kelly; McKinstry, Robert C.; Warren, William; Nishino, Tomoyuki; Robert Almli, C.; Todd, Richard; Constantino, John; McCracken, James T.; Levitt, Jennifer; Alger, Jeffrey; O'Neil, Joseph; Toga, Arthur; Asarnow, Robert; Fadale, David; Heinichen, Laura; Ireland, Cedric; Wang, Dah-Jyuu; Moss, Edward; Zimmerman, Robert A.; Bintliff, Brooke; Bradford, Ruth; Newman, Janice; Evans, Alan C.; Arnaoutelis, Rozalia; Bruce Pike, G.; Louis Collins, D.; Leonard, Gabriel; Paus, Tomas; Zijdenbos, Alex; Das, Samir; Fonov, Vladimir; Fu, Luke; Harlap, Jonathan; Leppert, Ilana; Milovan, Denise; Vins, Dario; Zeffiro, Thomas; Van Meter, John; Lange, Nicholas; Froimowitz, Michael P.; Botteron, Kelly; Robert Almli, C.; Rainey, Cheryl; Henderson, Stan; Nishino, Tomoyuki; Warren, William; Edwards, Jennifer L.; Dubois, Diane; Smith, Karla; Singer, Tish; Wilber, Aaron A.; Pierpaoli, Carlo; Basser, Peter J.; Chang, Lin-Ching; Koay, Chen Guan; Walker, Lindsay; Freund, Lisa; Rumsey, Judith; Baskir, Lauren; Stanford, Laurence; Sirocco, Karen; Gwinn-Hardy, Katrina; Spinella, Giovanna; McCracken, James T.; Alger, Jeffry R.; Levitt, Jennifer; O'Neill, Joseph

2013-01-01

Recent findings from developmental neuroimaging studies suggest that the enhancement of cognitive processes during development may be the result of a fine-tuning of the structural and functional organization of brain with maturation. However, the details regarding the developmental trajectory of large-scale structural brain networks are not yet understood. Here, we used graph theory to examine developmental changes in the organization of structural brain networks in 203 normally growing children and adolescents. Structural brain networks were constructed using interregional correlations in cortical thickness for 4 age groups (early childhood: 4.8–8.4 year; late childhood: 8.5–11.3 year; early adolescence: 11.4–14.7 year; late adolescence: 14.8–18.3 year). Late childhood showed prominent changes in topological properties, specifically a significant reduction in local efficiency, modularity, and increased global efficiency, suggesting a shift of topological organization toward a more random configuration. An increase in number and span of distribution of connector hubs was found in this age group. Finally, inter-regional connectivity analysis and graph-theoretic measures indicated early maturation of primary sensorimotor regions and protracted development of higher order association and paralimbic regions. Our finding reveals a time window of plasticity occurring during late childhood which may accommodate crucial changes during puberty and the new developmental tasks that an adolescent faces. PMID:22784607

Developmental changes in organization of structural brain networks.

PubMed

Khundrakpam, Budhachandra S; Reid, Andrew; Brauer, Jens; Carbonell, Felix; Lewis, John; Ameis, Stephanie; Karama, Sherif; Lee, Junki; Chen, Zhang; Das, Samir; Evans, Alan C

2013-09-01

Recent findings from developmental neuroimaging studies suggest that the enhancement of cognitive processes during development may be the result of a fine-tuning of the structural and functional organization of brain with maturation. However, the details regarding the developmental trajectory of large-scale structural brain networks are not yet understood. Here, we used graph theory to examine developmental changes in the organization of structural brain networks in 203 normally growing children and adolescents. Structural brain networks were constructed using interregional correlations in cortical thickness for 4 age groups (early childhood: 4.8-8.4 year; late childhood: 8.5-11.3 year; early adolescence: 11.4-14.7 year; late adolescence: 14.8-18.3 year). Late childhood showed prominent changes in topological properties, specifically a significant reduction in local efficiency, modularity, and increased global efficiency, suggesting a shift of topological organization toward a more random configuration. An increase in number and span of distribution of connector hubs was found in this age group. Finally, inter-regional connectivity analysis and graph-theoretic measures indicated early maturation of primary sensorimotor regions and protracted development of higher order association and paralimbic regions. Our finding reveals a time window of plasticity occurring during late childhood which may accommodate crucial changes during puberty and the new developmental tasks that an adolescent faces.

Hydrocephalus and arthrogryposis in an immunocompetent mouse model of ZIKA teratogeny: A developmental study

PubMed Central

Xavier-Neto, Jose; Carvalho, Murilo; Pascoalino, Bruno dos Santos; Cardoso, Alisson Campos; Costa, Ângela Maria Sousa; Pereira, Ana Helena Macedo; Santos, Luana Nunes; Saito, Ângela; Marques, Rafael Elias; Smetana, Juliana Helena Costa; Consonni, Silvio Roberto; Bandeira, Carla; Costa, Vivian Vasconcelos; Bajgelman, Marcio Chaim; de Oliveira, Paulo Sérgio Lopes; Cordeiro, Marli Tenorio; Gonzales Gil, Laura Helena Vega; Pauletti, Bianca Alves; Granato, Daniela Campos; Paes Leme, Adriana Franco; Freitas-Junior, Lucio; Holanda de Freitas, Carolina Borsoi Moraes; Teixeira, Mauro Martins; Bevilacqua, Estela; Franchini, Kleber

2017-01-01

The teratogenic mechanisms triggered by ZIKV are still obscure due to the lack of a suitable animal model. Here we present a mouse model of developmental disruption induced by ZIKV hematogenic infection. The model utilizes immunocompetent animals from wild-type FVB/NJ and C57BL/6J strains, providing a better analogy to the human condition than approaches involving immunodeficient, genetically modified animals, or direct ZIKV injection into the brain. When injected via the jugular vein into the blood of pregnant females harboring conceptuses from early gastrulation to organogenesis stages, akin to the human second and fifth week of pregnancy, ZIKV infects maternal tissues, placentas and embryos/fetuses. Early exposure to ZIKV at developmental day 5 (second week in humans) produced complex manifestations of anterior and posterior dysraphia and hydrocephalus, as well as severe malformations and delayed development in 10.5 days post-coitum (dpc) embryos. Exposure to the virus at 7.5–9.5 dpc induces intra-amniotic hemorrhage, widespread edema, and vascular rarefaction, often prominent in the cephalic region. At these stages, most affected embryos/fetuses displayed gross malformations and/or intrauterine growth restriction (IUGR), rather than isolated microcephaly. Disrupted conceptuses failed to achieve normal developmental landmarks and died in utero. Importantly, this is the only model so far to display dysraphia and hydrocephalus, the harbinger of microcephaly in humans, as well as arthrogryposis, a set of abnormal joint postures observed in the human setting. Late exposure to ZIKV at 12.5 dpc failed to produce noticeable malformations. We have thus characterized a developmental window of opportunity for ZIKV-induced teratogenesis encompassing early gastrulation, neurulation and early organogenesis stages. This should not, however, be interpreted as evidence for any safe developmental windows for ZIKV exposure. Late developmental abnormalities correlated with

Glossary | Efficient Windows Collaborative

Science.gov Websites

double-hung windows as a means of counterbalancing the weight of the sash during opening and closing. Bay a fixed sash or a double-hung window. Also referred to as bead stop. Blackbody. The ideal, perfect member of the lower sash which meet at the middle of a double-hung window. Clerestory. A window in the

Double window viewing chamber assembly

NASA Technical Reports Server (NTRS)

Keller, V. W. (Inventor); Owen, R. B. (Inventor); Elkins, B. R. (Inventor); White, W. T. (Inventor)

1986-01-01

A viewing chamber which permits observation of a sample retained therein includes a pair of double window assemblies mounted in opposed openings in the walls thereof so that a light beam can directly enter and exit from the chamber. A flexible mounting arrangement for the outer windows of the window assemblies enables the windows to be brought into proper alignment. An electrical heating arrangement prevents fogging of the outer windows whereas desiccated air in the volume between the outer and inner windows prevents fogging of the latter.

Influence of Conduct Problems and Depressive Symptomatology on Adolescent Substance Use: Developmentally Proximal versus Distal Effects

ERIC Educational Resources Information Center

Maslowsky, Julie; Schulenberg, John E.; Zucker, Robert A.

2014-01-01

The identification of developmentally specific windows at which key predictors of adolescent substance use are most influential is a crucial task for informing the design of appropriately targeted substance use prevention and intervention programs. The current study examined effects of conduct problems and depressive symptomatology on changes in…

Child Health, Developmental Plasticity, and Epigenetic Programming

PubMed Central

Feil, R.; Constancia, M.; Fraga, M.; Junien, C.; Carel, J.-C.; Boileau, P.; Le Bouc, Y.; Deal, C. L.; Lillycrop, K.; Scharfmann, R.; Sheppard, A.; Skinner, M.; Szyf, M.; Waterland, R. A.; Waxman, D. J.; Whitelaw, E.; Ong, K.; Albertsson-Wikland, K.

2011-01-01

Plasticity in developmental programming has evolved in order to provide the best chances of survival and reproductive success to the organism under changing environments. Environmental conditions that are experienced in early life can profoundly influence human biology and long-term health. Developmental origins of health and disease and life-history transitions are purported to use placental, nutritional, and endocrine cues for setting long-term biological, mental, and behavioral strategies in response to local ecological and/or social conditions. The window of developmental plasticity extends from preconception to early childhood and involves epigenetic responses to environmental changes, which exert their effects during life-history phase transitions. These epigenetic responses influence development, cell- and tissue-specific gene expression, and sexual dimorphism, and, in exceptional cases, could be transmitted transgenerationally. Translational epigenetic research in child health is a reiterative process that ranges from research in the basic sciences, preclinical research, and pediatric clinical research. Identifying the epigenetic consequences of fetal programming creates potential applications in clinical practice: the development of epigenetic biomarkers for early diagnosis of disease, the ability to identify susceptible individuals at risk for adult diseases, and the development of novel preventive and curative measures that are based on diet and/or novel epigenetic drugs. PMID:20971919

Neurogenesis and Developmental Anesthetic Neurotoxicity

PubMed Central

Kang, Eunchai; Berg, Daniel A.; Furmanski, Orion; Jackson, William M.; Ryu, Yun Kyoung; Gray, Christy D.; Mintz, C. David

2017-01-01

The mechanism by which anesthetics might act on the developing brain in order to cause long term deficits remains incompletely understood. The hippocampus has been identified as a structure that is likely to be involved, as rodent models show numerous deficits in behavioral tasks of learning that are hippocampal-dependent. The hippocampus is an unusual structure in that it is the site of large amounts of neurogenesis postnatally, particularly in the first year of life in humans, and these newly generated neurons are critical to the function of this structure. Intriguingly, neurogenesis is a major developmental event that occurs during postulated windows of vulnerability to developmental anesthetic neurotoxicity across the different species in which it has been studied. In this review, we examine the evidence for anesthetic effects on neurogenesis in the early postnatal period and ask whether neurogenesis should be studied further as a putative mechanism of injury. Multiple anesthetics are considered, and both in vivo and in vitro work is presented. While there is abundant evidence that anesthetics act to suppress neurogenesis at several different phases, evidence of a causal link between these effects and any change in learning behavior remains elusive. PMID:27751818

Lagged kernel machine regression for identifying time windows of susceptibility to exposures of complex mixtures.

PubMed

Liu, Shelley H; Bobb, Jennifer F; Lee, Kyu Ha; Gennings, Chris; Claus Henn, Birgit; Bellinger, David; Austin, Christine; Schnaas, Lourdes; Tellez-Rojo, Martha M; Hu, Howard; Wright, Robert O; Arora, Manish; Coull, Brent A

2018-07-01

The impact of neurotoxic chemical mixtures on children's health is a critical public health concern. It is well known that during early life, toxic exposures may impact cognitive function during critical time intervals of increased vulnerability, known as windows of susceptibility. Knowledge on time windows of susceptibility can help inform treatment and prevention strategies, as chemical mixtures may affect a developmental process that is operating at a specific life phase. There are several statistical challenges in estimating the health effects of time-varying exposures to multi-pollutant mixtures, such as: multi-collinearity among the exposures both within time points and across time points, and complex exposure-response relationships. To address these concerns, we develop a flexible statistical method, called lagged kernel machine regression (LKMR). LKMR identifies critical exposure windows of chemical mixtures, and accounts for complex non-linear and non-additive effects of the mixture at any given exposure window. Specifically, LKMR estimates how the effects of a mixture of exposures change with the exposure time window using a Bayesian formulation of a grouped, fused lasso penalty within a kernel machine regression (KMR) framework. A simulation study demonstrates the performance of LKMR under realistic exposure-response scenarios, and demonstrates large gains over approaches that consider each time window separately, particularly when serial correlation among the time-varying exposures is high. Furthermore, LKMR demonstrates gains over another approach that inputs all time-specific chemical concentrations together into a single KMR. We apply LKMR to estimate associations between neurodevelopment and metal mixtures in Early Life Exposures in Mexico and Neurotoxicology, a prospective cohort study of child health in Mexico City.

An aqueous electrolyte of the widest potential window and its superior capability for capacitors.

PubMed

Tomiyasu, Hiroshi; Shikata, Hirokazu; Takao, Koichiro; Asanuma, Noriko; Taruta, Seiichi; Park, Yoon-Yul

2017-03-21

A saturated aqueous solution of sodium perchlorate (SSPAS) was found to be electrochemically superior, because the potential window is remarkably wide to be approximately 3.2 V in terms of a cyclic voltammetry. Such a wide potential window has never been reported in any aqueous solutions, and this finding would be of historical significance for aqueous electrolyte to overcome its weak point that the potential window is narrow. In proof of this fact, the capability of SSPAS was examined for the electrolyte of capacitors. Galvanostatic charge-discharge measurements showed that a graphite-based capacitor containing SSPAS as an electrolyte was stable within 5% deviation for the 10,000 times repetition at the operating voltage of 3.2 V without generating any gas. The SSPAS worked also as a functional electrolyte in the presence of an activated carbon and metal oxides in order to increase an energy density. Indeed, in an asymmetric capacitor containing MnO 2 and Fe 3 O 4 mixtures in the positive and negative electrodes, respectively, the energy density enlarged to be 36.3 Whkg -1 , which belongs to the largest value in capacitors. Similar electrochemical behaviour was also confirmed in saturated aqueous solutions of other alkali and alkaline earth metal perchlorate salts.

An aqueous electrolyte of the widest potential window and its superior capability for capacitors

PubMed Central

Tomiyasu, Hiroshi; Shikata, Hirokazu; Takao, Koichiro; Asanuma, Noriko; Taruta, Seiichi; Park, Yoon-Yul

2017-01-01

A saturated aqueous solution of sodium perchlorate (SSPAS) was found to be electrochemically superior, because the potential window is remarkably wide to be approximately 3.2 V in terms of a cyclic voltammetry. Such a wide potential window has never been reported in any aqueous solutions, and this finding would be of historical significance for aqueous electrolyte to overcome its weak point that the potential window is narrow. In proof of this fact, the capability of SSPAS was examined for the electrolyte of capacitors. Galvanostatic charge-discharge measurements showed that a graphite-based capacitor containing SSPAS as an electrolyte was stable within 5% deviation for the 10,000 times repetition at the operating voltage of 3.2 V without generating any gas. The SSPAS worked also as a functional electrolyte in the presence of an activated carbon and metal oxides in order to increase an energy density. Indeed, in an asymmetric capacitor containing MnO2 and Fe3O4 mixtures in the positive and negative electrodes, respectively, the energy density enlarged to be 36.3 Whkg−1, which belongs to the largest value in capacitors. Similar electrochemical behaviour was also confirmed in saturated aqueous solutions of other alkali and alkaline earth metal perchlorate salts. PMID:28322349

A view of metals through the terahertz window

NASA Astrophysics Data System (ADS)

Dodge, Steve

2006-05-01

As electrons move through a metal, interaction with their environment tends to slow them down, causing the Drude peak in the optical conductivity to become narrower. The resulting peak width is typically in the terahertz frequency range that sits between microwaves the far infrared, too fast for conventional electronics and too slow for conventional infrared spectroscopy. With femtosecond laser techniques, however, coherent, broadband terahertz radiation can now be generated and detected with exquisite sensitivity, providing a new window onto electronic interactions in metals. I will discuss the application of this technique to a variety of metallic systems, including elemental lead, the nearly magnetic oxide metal CaRuO3, and CrV alloys that span the quantum phase transition from spin-density wave to paramagnetic metal. M. A. Gilmore, S. Kamal, D. M. Broun, and J. S. Dodge, Appl. Phys. Lett. 88, 141910 (2006).

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Compound curvature laser window development

NASA Technical Reports Server (NTRS)

Verhoff, Vincent G.

1993-01-01

The NASA Lewis Research Center has developed and implemented a unique process for forming flawless compound curvature laser windows. These windows represent a major part of specialized, nonintrusive laser data acquisition systems used in a variety of compressor and turbine research test facilities. This report summarizes the main aspects of compound curvature laser window development. It is an overview of the methodology and the peculiarities associated with the formulation of these windows. Included in this discussion is new information regarding procedures for compound curvature laser window development.

Three-dimensional laser window formation

NASA Technical Reports Server (NTRS)

Verhoff, Vincent G.

1992-01-01

The NASA Lewis Research Center has developed and implemented a unique process for forming flawless three-dimensional laser windows. These windows represent a major part of specialized, nonintrusive laser data acquisition systems used in a variety of compressor and turbine research test facilities. This report discusses in detail the aspects of three-dimensional laser window formation. It focuses on the unique methodology and the peculiarities associated with the formation of these windows. Included in this discussion are the design criteria, bonding mediums, and evaluation testing for three-dimensional laser windows.

Music@Microsoft.Windows: Composing Ambience

ERIC Educational Resources Information Center

Rickert, Thomas

2010-01-01

It is well known, of course, that all Windows versions except for 3.1 have a brief (four to six second) piece of music indicating that Windows is booted and ready for use. While the music may indicate Windows has booted, it bears no immediately discernable relation to the various uses we might actually put Windows to--working, gaming,…

A Window-Washing Challenge

ERIC Educational Resources Information Center

Roman, Harry T.

2010-01-01

Skyscrapers sure do have a lot of windows, and these windows are cleaned and checked regularly. All this takes time, money, and puts workers at potential risk. Might there be a better way to do it? In this article, the author discusses a window-washing challenge and describes how students can tackle this task, pick up the challenge, and creatively…

Tuning the chemosensory window

PubMed Central

Zhou, Shanshan; Mackay, Trudy FC

2010-01-01

Accurate perception of chemical signals from the environment is critical for the fitness of most animals. Drosophila melanogaster experiences its chemical environment through families of chemoreceptors that include olfactory receptors, gustatory receptors and odorant binding proteins. Its chemical environment, however, changes during its life cycle and the interpretation of chemical signals is dependent on dynamic social and physical surroundings. Phenotypic plasticity of gene expression of the chemoreceptor repertoire allows flies to adjust the chemosensory window through which they “view” their world and to modify the ensemble of expressed chemoreceptor proteins in line with their developmental and physiological state and according to their needs to locate food and oviposition sites under different social and physical environmental conditions. Furthermore, males and females differ in their expression profiles of chemoreceptor genes. Thus, each sex experiences its chemical environment via combinatorial activation of distinct chemoreceptor ensembles. The remarkable phenotypic plasticity of the chemoreceptor repertoire raises several fundamental questions. What are the mechanisms that translate environmental cues into regulation of chemoreceptor gene expression? How are gustatory and olfactory cues integrated perceptually? What is the relationship between ensembles of odorant binding proteins and odorant receptors? And, what is the significance of co-regulated chemoreceptor transcriptional networks? PMID:20305396

The Narrow-Line Region of Narrow-Line Seyfert 1 Galaxies

NASA Astrophysics Data System (ADS)

Rodríguez-Ardila, A.; Binette, Luc; Pastoriza, Miriani G.; Donzelli, Carlos J.

2000-08-01

This work studies the optical emission-line properties and physical conditions of the narrow-line region (NLR) of seven narrow-line Seyfert 1 galaxies (NLS1's) for which high signal-to-noise ratio spectroscopic observations were available. The resolution is 340 km s-1 (at Hα) over the wavelength interval 3700-9500 Å, enabling us to separate the broad and narrow components of the permitted emission lines. Our results show that the flux carried out by the narrow component of Hβ is, on average, 50% of the total line flux. As a result, the [O III] λ5007/Hβ ratio emitted in the NLR varies from 1 to 5, instead of the universally adopted value of 10. This has strong implications for the required spectral energy distribution that ionizes the NLR gas. Photoionization models that consider a NLR composed of a combination of matter-bounded and ionization-bounded clouds are successful at explaining the low [O III] λ5007/Hβ ratio and the weakness of low-ionization lines of NLS1's. Variation of the relative proportion of these two type of clouds nicely reproduces the dispersion of narrow-line ratios found among the NLS1 sample. Assuming similar physical model parameters of both NLS1's and the normal Seyfert 1 galaxy NGC 5548, we show that the observed differences of emission-line ratios between these two groups of galaxies can be explained, to a first approximation, in terms of the shape of the input ionizing continuum. Narrow emission-line ratios of NLS1's are better reproduced by a steep power-law continuum in the EUV-soft X-ray region, with spectral index α~-2. Flatter spectral indices (α~-1.5) match the observed line ratios of NGC 5548 but are unable to provide a good match to the NLS1 ratios. This result is consistent with ROSAT observations of NLS1's, which show that these objects are characterized by steeper power-law indices than those of Seyfert 1 galaxies with strong broad optical lines. Based on observations made at CASLEO. Complejo Astronómico El Leoncito

Signal and noise level estimation for narrow spectral width returns observed by the Indian MST radar

NASA Astrophysics Data System (ADS)

Hooper, D. A.

1999-07-01

Use is made of five sets of multibeam observations of the lower atmosphere made by the Indian mesosphere-stratosphere-troposphere (MST) radar. Two aspects of signal processing which can lead to serious underestimates of the signal-to-noise ratio are considered. First, a comparison is made of the effects of different data weighting windows applied to the inphase and quadrature components of the radar return samples prior to Fourier transformation. The relatively high degree of spectral leakage associated with the rectangular and Hamming windows can give rise to overestimates of the noise levels by up to 28 dB for the strongest signals. Use of the Hanning window is found to be the most appropriate for these particular data. Second, a technique for removing systematic dc biases from the data in the time domain is compared with the more well-known practice of correction in the frequency domain. The latter technique, which is often used to remove the effects of ground clutter, is shown to be particularly inappropriate for the characteristically narrow spectral width signals observed by the Indian MST radar. For cases of near-zero Doppler shift it can remove up to 30 dB of signal information. The consequences of noise and signal level discrepancies for studies of refractivity structures are discussed. It is shown that neither problem has a significant effect on Doppler shift or spectral width estimates.

Monoamine-Sensitive Developmental Periods Impacting Adult Emotional and Cognitive Behaviors

PubMed Central

Suri, Deepika; Teixeira, Cátia M; Cagliostro, Martha K Caffrey; Mahadevia, Darshini; Ansorge, Mark S

2015-01-01

Development passes through sensitive periods, during which plasticity allows for genetic and environmental factors to exert indelible influence on the maturation of the organism. In the context of central nervous system development, such sensitive periods shape the formation of neurocircuits that mediate, regulate, and control behavior. This general mechanism allows for development to be guided by both the genetic blueprint as well as the environmental context. While allowing for adaptation, such sensitive periods are also vulnerability windows during which external and internal factors can confer risk to disorders by derailing otherwise resilient developmental programs. Here we review developmental periods that are sensitive to monoamine signaling and impact adult behaviors of relevance to psychiatry. Specifically, we review (1) a serotonin-sensitive period that impacts sensory system development, (2) a serotonin-sensitive period that impacts cognition, anxiety- and depression-related behaviors, and (3) a dopamine- and serotonin-sensitive period affecting aggression, impulsivity and behavioral response to psychostimulants. We discuss preclinical data to provide mechanistic insight, as well as epidemiological and clinical data to point out translational relevance. The field of translational developmental neuroscience has progressed exponentially providing solid conceptual advances and unprecedented mechanistic insight. With such knowledge at hand and important methodological innovation ongoing, the field is poised for breakthroughs elucidating the developmental origins of neuropsychiatric disorders, and thus understanding pathophysiology. Such knowledge of sensitive periods that determine the developmental trajectory of complex behaviors is a necessary step towards improving prevention and treatment approaches for neuropsychiatric disorders. PMID:25178408

Developmental pathways in infants from 4 to 24 months.

PubMed

Valla, L; Birkeland, M S; Hofoss, D; Slinning, K

2017-07-01

There has been limited epidemiological research describing population-based samples regarding developmental pathways throughout infancy, and the research that exists has revealed substantial diversity. Identifying predictors for developmental pathways can inform early intervention services. The Ages and Stages Questionnaire was used to measure communication, gross motor, fine motor, problem-solving and personal-social skills longitudinally in a large, population-based sample of 1555 infants recruited from well-baby clinics in five municipalities in southeast Norway. We conducted latent class analyses to identify common pathways within the five developmental areas. Our results indicated that most classes of infants showed generally positive and stable normative developmental pathways. However, for communication and gross motor areas, more heterogeneity was found. For gross motor development, a class of 10% followed a U-shaped curve. A class of 8% had a declining communication pathway and did not reach the level of the high stable communication class at 24 months. Low gestational age, low Apgar score, male sex, maternal depression symptoms, non-Scandinavian maternal ethnicity and high maternal education significantly predict less beneficial communication pathways. The results suggest that infants with low gestational age, low Apgar score, male sex and a mother with depression symptoms or non-Scandinavian ethnicity may be at risk of developing less beneficial developmental pathways, especially within the communication area. Targeting these infants for surveillance and support might be protective against delayed development in several areas during a critical window of development. © 2017 John Wiley & Sons Ltd.

Neurogenesis and developmental anesthetic neurotoxicity.

PubMed

Kang, Eunchai; Berg, Daniel A; Furmanski, Orion; Jackson, William M; Ryu, Yun Kyoung; Gray, Christy D; Mintz, C David

The mechanism by which anesthetics might act on the developing brain in order to cause long term deficits remains incompletely understood. The hippocampus has been identified as a structure that is likely to be involved, as rodent models show numerous deficits in behavioral tasks of learning that are hippocampal-dependent. The hippocampus is an unusual structure in that it is the site of large amounts of neurogenesis postnatally, particularly in the first year of life in humans, and these newly generated neurons are critical to the function of this structure. Intriguingly, neurogenesis is a major developmental event that occurs during postulated windows of vulnerability to developmental anesthetic neurotoxicity across the different species in which it has been studied. In this review, we examine the evidence for anesthetic effects on neurogenesis in the early postnatal period and ask whether neurogenesis should be studied further as a putative mechanism of injury. Multiple anesthetics are considered, and both in vivo and in vitro work is presented. While there is abundant evidence that anesthetics act to suppress neurogenesis at several different phases, evidence of a causal link between these effects and any change in learning behavior remains elusive. Copyright © 2016. Published by Elsevier Inc.

Conformal ALON® and spinel windows

NASA Astrophysics Data System (ADS)

Goldman, Lee M.; Smith, Mark; Ramisetty, Mohan; Jha, Santosh; Sastri, Suri

2017-05-01

The requirements for modern aircraft based reconnaissance systems are driving the need for conformal windows for future sensor systems. However, limitations on optical systems and the ability to produce windows in complex geometries currently limit the geometry of existing windows and window assemblies to faceted assemblies of flat windows. ALON consists primarily of aluminum and oxygen, similar to that of alumina, with a small amount of nitrogen added to help stabilize the cubic gamma-AlON phase. ALON's chemical similarity to alumina, translates into a robust manufacturing process. This ease of processing has allowed Surmet to produce ALON windows and domes in a wide variety of geometries and sizes. Spinel (MgAl2O4) contains equal molar amounts of MgO and Al2O3, and is a cubic material, that transmits further into the Infrared than ALON. Spinel is produced via powder processing techniques similar to those used to produce ALON. Surmet is now applying the lessons learned with ALON to produce conformal spinel windows and domes as well.

Color Wheel Windows

ERIC Educational Resources Information Center

Leonard, Stephanie

2012-01-01

In this article, the author describes a painting and drawing lesson which was inspired by the beautiful circular windows found in cathedrals and churches (also known as "rose windows"). This two-week lesson would reinforce both the concept of symmetry and students' understanding of the color wheel. (Contains 1 online resource.)

Technical Note: Display window setting: An important factor for detecting subtle but clinically relevant artifacts in daily CT quality control.

PubMed

Long, Zaiyang; Bruesewitz, Michael R; Sheedy, Emily N; Powell, Michele A; Kramer, Jacqualynn C; Supalla, Randall R; Colvin, Chance M; Bechel, Jessica R; Favazza, Christopher P; Kofler, James M; Leng, Shuai; McCollough, Cynthia H; Yu, Lifeng

2016-12-01

This study aimed to investigate the influence of display window setting on technologist performance detecting subtle but clinically relevant artifacts in daily computed tomography (CT) quality control (dQC) images. Fifty three sets of dQC images were retrospectively selected, including 30 sets without artifacts, and 23 with subtle but clinically relevant artifacts. They were randomized and shown to six CT technologists (two new and four experienced). Each technologist reviewed all images in each of two sessions, one with a display window width (WW) of 100 HU, which is currently recommended by the American College of Radiology, and the other with a narrow WW of 40 HU, both at a window level of 0 HU. For each case, technologists rated the presence of image artifacts based on a five point scale. The area under the receiver operating characteristic curve (AUC) was used to evaluate the artifact detection performance. At a WW of 100 HU, the AUC (95% confidence interval) was 0.658 (0.576, 0.740), 0.532 (0.429, 0.635), and 0.616 (0.543, 0.619) for the experienced, new, and all technologists, respectively. At a WW of 40 HU, the AUC was 0.768 (0.687, 0.850), 0.546 (0.433, 0.658), and 0.694 (0.619, 0.769), respectively. The performance significantly improved at WW of 40 HU for experienced technologists (p = 0.009) and for all technologists (p = 0.040). Use of a narrow display WW significantly improved technologists' performance in dQC for detecting subtle but clinically relevant artifacts as compared to that using a 100 HU display WW.

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Selection Tool Mobile App Window Selection Tool Mobile App Use the Window Selection Tool Mobile App for new Window Selection Tool Mobile App. LBNL's RESFEN RESFEN RESFEN is used for calculating the heating and

Two-Band, Low-Loss Microwave Window

NASA Technical Reports Server (NTRS)

Britcliffe, Michael; Franco, Manuel

2007-01-01

A window for a high-sensitivity microwave receiving system allows microwave radiation to pass through to a cryogenically cooled microwave feed system in a vacuum chamber, while keeping ambient air out of the chamber and helping to keep the interior of the chamber cold. The microwave feed system comprises a feed horn and a low-noise amplifier, both of which are required to be cooled to a temperature of 15 K during operation. The window is designed to exhibit very little microwave attenuation in two frequency bands: 8 to 9 GHz and 30 to 40 GHz. The window is 15 cm in diameter. It includes three layers (see figure): 1) The outer layer is made of a poly(tetrafluoroethylene) film 0.025 mm thick. This layer serves primarily to reflect and absorb solar ultraviolet radiation to prolong the life of the underlying main window layer, which is made of a polyimide that becomes weakened when exposed to ultraviolet. The poly(tetrafluoroethylene) layer also protects the main window layer against abrasion. Moreover, the inherent hydrophobicity of poly(tetrafluoroethylene) helps to prevent the highly undesirable accumulation of water on the outer surface. 2) The polyimide main window layer is 0.08 mm thick. This layer provides the vacuum seal for the window. 3) A 20-mm-thick layer of ethylene/ propylene copolymer foam underlies the main polyimide window layer. This foam layer acts partly as a thermal insulator: it limits radiational heating of the microwave feed horn and, concomitantly, limits radiational cooling of the window. This layer has high compressive strength and provides some mechanical support for the main window layer, reducing the strength required of the main window layer. The ethylene/propylene copolymer foam layer is attached to an aluminum window ring by means of epoxy. The outer poly(tetrafluoroethylene) film and the main polyimide window layer are sandwiched together and pressed against the window ring by use of a bolted clamp ring. The window has been found to

False Windows - Yesterday and Today

NASA Astrophysics Data System (ADS)

Niewitecki, Stefan

2017-10-01

The article is concerned with a very interesting aspect of architectural design, namely, a contradiction between the building functions and the necessity of giving the building a desired external appearance. One of the possibilities of reconciling this contradiction is using pseudo windows that are visible on the elevation and generally have the form of a black painted recess accompanied by frames and sashes and often single glazing. Of course, there are no windows or openings in the corresponding places in the walls inside the building. The article discusses the differences between false windows and blind widows (German: blende), also known as blank windows, which, in fact, are shallow recesses in the wall having the external appearance of an arcade or a window and which had already been used in Gothic architecture mostly for aesthetic reasons and sometimes to reduce the load of the wall. Moreover, the article describes various false windows that appeared later than blind windows because they did not appear until the 17th century. Contemporary false windows are also discussed and it is shown that contrary to the common belief they are widely used. In his research, the author not only used the Internet data but also carried out his own in situ exploration. The false windows constitute very interesting albeit rare elements of the architectural design of buildings. They have been used successfully for a few hundred years. It might seem that they should have been discarded by now but this has not happened. Quite contrary, since the second half of the 20th century there has been a rapid development of glass curtain walls that serve a similar function in contemporary buildings as the false windows once did, only in a more extensive way.

A Numerical Study of the Thermal Characteristics of an Air Cavity Formed by Window Sashes in a Double Window

NASA Astrophysics Data System (ADS)

Kang, Jae-sik; Oh, Eun-Joo; Bae, Min-Jung; Song, Doo-Sam

2017-12-01

Given that the Korean government is implementing what has been termed the energy standards and labelling program for windows, window companies will be required to assign window ratings based on the experimental results of their product. Because this has added to the cost and time required for laboratory tests by window companies, the simulation system for the thermal performance of windows has been prepared to compensate for time and cost burdens. In Korea, a simulator is usually used to calculate the thermal performance of a window through WINDOW/THERM, complying with ISO 15099. For a single window, the simulation results are similar to experimental results. A double window is also calculated using the same method, but the calculation results for this type of window are unreliable. ISO 15099 should not recommend the calculation of the thermal properties of an air cavity between window sashes in a double window. This causes a difference between simulation and experimental results pertaining to the thermal performance of a double window. In this paper, the thermal properties of air cavities between window sashes in a double window are analyzed through computational fluid dynamics (CFD) simulations with the results compared to calculation results certified by ISO 15099. The surface temperature of the air cavity analyzed by CFD is compared to the experimental temperatures. These results show that an appropriate calculation method for an air cavity between window sashes in a double window should be established for reliable thermal performance results for a double window.

Adaptive Liquid Crystal Windows

DOE Office of Scientific and Technical Information (OSTI.GOV)

Taheri, Bahman; Bodnar, Volodymyr

2011-12-31

Energy consumption by private and commercial sectors in the U.S. has steadily grown over the last decade. The uncertainty in future availability of imported oil, on which the energy consumption relies strongly, resulted in a dramatic increase in the cost of energy. About 20% of this consumption are used to heat and cool houses and commercial buildings. To reduce dependence on the foreign oil and cut down emission of greenhouse gases, it is necessary to eliminate losses and reduce total energy consumption by buildings. To achieve this goal it is necessary to redefine the role of the conventional windows. Atmore » a minimum, windows should stop being a source for energy loss. Ideally, windows should become a source of energy, providing net gain to reduce energy used to heat and cool homes. It is possible to have a net energy gain from a window if its light transmission can be dynamically altered, ideally electronically without the need of operator assistance, providing optimal control of the solar gain that varies with season and climate in the U.S. In addition, the window must not require power from the building for operation. Resolution of this problem is a societal challenge and of national interest and will have a broad global impact. For this purpose, the year-round, allclimate window solution to provide an electronically variable solar heat gain coefficient (SHGC) with a wide dynamic range is needed. AlphaMicron, Inc. (AMI) developed and manufactured 1ft × 1ft prototype panels for the world’s first auto-adjusting Adaptive Liquid Crystal Windows (ALCWs) that can operate from sunlight without the need for external power source and demonstrate an electronically adjustable SHGC. This novel windows are based on AlphaMicron’s patented e-Tint® technology, a guesthost liquid crystal system implemented on flexible, optically clear plastic films. This technology is suitable both for OEM and aftermarket (retro-fitting) lamination to new and existing windows. Low

Prism Window for Optical Alignment

NASA Technical Reports Server (NTRS)

Tang, Hong

2008-01-01

A prism window has been devised for use, with an autocollimator, in aligning optical components that are (1) required to be oriented parallel to each other and/or at a specified angle of incidence with respect to a common optical path and (2) mounted at different positions along the common optical path. The prism window can also be used to align a single optical component at a specified angle of incidence. Prism windows could be generally useful for orienting optical components in manufacture of optical instruments. "Prism window" denotes an application-specific unit comprising two beam-splitter windows that are bonded together at an angle chosen to obtain the specified angle of incidence.

Removable Window System for Space Vehicles

NASA Technical Reports Server (NTRS)

Grady, James P. (Inventor)

2015-01-01

A window system for a platform comprising a window pane, a retention frame, and a biasing system. The window pane may be configured to contact a sealing system. The retention frame may be configured to contact the sealing system and hold the window pane against the support frame. The biasing system may be configured to bias the retention frame toward the support frame while the support frame and the retention frame are in a configuration that holds the window pane. Removal of the biasing system may cause the retention frame and the window pane to be removable.

High-impact resistance optical sensor windows

NASA Astrophysics Data System (ADS)

Askinazi, Joel; Ceccorulli, Mark L.; Goldman, Lee

2011-06-01

Recent field experience with optical sensor windows on both ground and airborne platforms has shown a significant increase in window fracturing from foreign object debris (FOD) impacts and as a by-product of asymmetrical warfare. Common optical sensor window materials such as borosilicate glass do not typically have high impact resistance. Emerging advanced optical window materials such as aluminum oxynitride offer the potential for a significant improvement in FOD impact resistance due to their superior surface hardness, fracture toughness and strength properties. To confirm the potential impact resistance improvement achievable with these emerging materials, Goodrich ISR Systems in collaboration with Surmet Corporation undertook a set of comparative FOD impact tests of optical sensor windows made from borosilicate glass and from aluminum oxynitride. It was demonstrated that the aluminum oxynitride windows could withstand up to three times the FOD impact velocity (as compared with borosilicate glass) before fracture would occur. These highly encouraging test results confirm the utility of this new highly viable window solution for use on new ground and airborne window multispectral applications as well as a retrofit to current production windows. We believe that this solution can go a long way to significantly reducing the frequency and life cycle cost of window replacement.

Window-closing safety system

DOEpatents

McEwan, Thomas E.

1997-01-01

A safety device includes a wire loop embedded in the glass of a passenger car window and routed near the closing leading-edge of the window. The wire loop carries microwave pulses around the loop to and from a transceiver with separate output and input ports. An evanescent field only and inch or two in radius is created along the wire loop by the pulses. Just about any object coming within the evanescent field will dramatically reduce the energy of the microwave pulses received back by the transceiver. Such a loss in energy is interpreted as a closing area blockage, and electrical interlocks are provided to halt or reverse a power window motor that is actively trying to close the window.

Window-closing safety system

DOEpatents

McEwan, T.E.

1997-08-26

A safety device includes a wire loop embedded in the glass of a passenger car window and routed near the closing leading-edge of the window. The wire loop carries microwave pulses around the loop to and from a transceiver with separate output and input ports. An evanescent field only an inch or two in radius is created along the wire loop by the pulses. Just about any object coming within the evanescent field will dramatically reduce the energy of the microwave pulses received back by the transceiver. Such a loss in energy is interpreted as a closing area blockage, and electrical interlocks are provided to halt or reverse a power window motor that is actively trying to close the window. 5 figs.

Digitized detection of gamma-ray signals concentrated in narrow time windows for transient positron annihilation lifetime spectroscopy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kinomura, A., E-mail: a.kinomura@aist.go.jp; Suzuki, R.; Oshima, N.

2014-12-15

A pulsed slow-positron beam generated by an electron linear accelerator was directly used for positron annihilation lifetime spectroscopy without any positron storage devices. A waveform digitizer was introduced to simultaneously capture multiple gamma-ray signals originating from positron annihilation events during a single accelerator pulse. The positron pulse was chopped and bunched with the chopper signals also sent to the waveform digitizer. Time differences between the annihilation gamma-ray and chopper peaks were calculated and accumulated as lifetime spectra in a computer. The developed technique indicated that positron annihilation lifetime spectroscopy can be performed in a 20 μs time window at amore » pulse repetition rate synchronous with the linear accelerator. Lifetime spectra of a Kapton sheet and a thermally grown SiO{sub 2} layer on Si were successfully measured. Synchronization of positron lifetime measurements with pulsed ion irradiation was demonstrated by this technique.« less

Digitized detection of gamma-ray signals concentrated in narrow time windows for transient positron annihilation lifetime spectroscopy

NASA Astrophysics Data System (ADS)

Kinomura, A.; Suzuki, R.; Oshima, N.; O'Rourke, B. E.; Nishijima, T.; Ogawa, H.

2014-12-01

A pulsed slow-positron beam generated by an electron linear accelerator was directly used for positron annihilation lifetime spectroscopy without any positron storage devices. A waveform digitizer was introduced to simultaneously capture multiple gamma-ray signals originating from positron annihilation events during a single accelerator pulse. The positron pulse was chopped and bunched with the chopper signals also sent to the waveform digitizer. Time differences between the annihilation gamma-ray and chopper peaks were calculated and accumulated as lifetime spectra in a computer. The developed technique indicated that positron annihilation lifetime spectroscopy can be performed in a 20 μs time window at a pulse repetition rate synchronous with the linear accelerator. Lifetime spectra of a Kapton sheet and a thermally grown SiO2 layer on Si were successfully measured. Synchronization of positron lifetime measurements with pulsed ion irradiation was demonstrated by this technique.

Cyclopamine-induced synophthalmia in sheep: defining a critical window and toxicokinetic evaluation.

PubMed

Welch, K D; Panter, K E; Lee, S T; Gardner, D R; Stegelmeier, B L; Cook, D

2009-07-01

Cyclopamine, a steroidal alkaloid, from the plant Veratrum californicum is teratogenic, causing a range of different birth defects. The critical window for cyclopamine-induced synophthalmia formation has been reported to be gestational day (GD) 14. The objectives of this study were to better describe cyclopamine-induced craniofacial deformities, to better define the window of susceptibility to synophthalmia formation, and to characterize cyclopamine toxicokinetics in sheep. Ewes were dosed i.v. with purified cyclopamine for toxicokinetic analysis. Another four groups of ewes were dosed orally twice daily with 0.88 g/kg of V. californicum on GD 13, 14 or 15 or consecutively on GD days 13-15. Pregnancy and pre-partum fetal malformations were determined by ultrasound imaging on GD 60. At parturition lambs were assessed for gross malformations. The elimination half-life of cyclopamine in ewes was determined to be 1.1 +/- 0.1 h. The rapid clearance of cyclopamine indicates that ingestion of V. californicum must occur during a very narrow window for synophthalmia formation to occur. Ewes dosed with V. californicum on GD 13 or 14 had lambs with various craniofacial malformations including cyclopia, maxillary dysplasia and mandibular micrognathia. Ewes dosed on GD 15 delivered normal lambs. Ewes dosed consecutively on GD 13-15 were not pregnant at GD 60 and Veratrum-induced embryonic death was assumed to be the cause. Interestingly, lambs with cyclopia were smaller, under-developed and appeared premature even though their twin appeared fully developed. Initial evaluations suggest this was due to placental dysplasia. 2009 by John Wiley & Sons, Ltd.

Right-to-left-shunt detected by c-TCD using the orbital window in comparison with temporal bone windows.

PubMed

Kobayashi, Kazuto; Kimura, Kazumi; Iguchi, Yasuyuki; Sakai, Kenichirou; Aoki, Junya; Iwanaga, Takeshi; Shibazaki, Kensaku

2012-01-01

There have been some reports on right-to-left shunt as a cause of cryptogenic stroke. Although contrast transcranial Doppler (c-TCD) can detect RLS, an insufficient temporal window has occasionally restricted its applicability. Thus, we compared the rates of detecting RLS among temporal windows for the middle cerebral arteries (MCAs) and the orbital window for the internal carotid artery (ICA) on c-TCD. We used c-TCD to detect RLS in patients with suspected ischemic stroke. We enrolled patients who had both sufficient bilateral temporal windows for MCAs and a right orbital window for ICA and performed c-TCD using all three windows simultaneously. We enrolled 106 consecutive patients and identified microembolic signals (MES) in 30 (28%) of them. Among these 30 patients, 15 had MES from all 3 windows. When these 30 patients were defined as being positive for RLS, the rates of detection were 67%, 73%, and 80% from the right temporal, left temporal, and right orbital windows, respectively (P= .795). The right orbital window as well as the temporal window for c-TCD could detect RLS. Insonation from the orbital window should be useful for patients who lack temporal windows. Copyright © 2010 by the American Society of Neuroimaging.

Exposure to suboptimal temperatures during metamorphosis reveals a critical developmental window in the solitary bee, Megachile rotundata

USDA-ARS?s Scientific Manuscript database

Metamorphosis is an important developmental stage for holometabolous insects, during which adult morphology and physiology are established. Proper development relies on optimal body temperatures, and natural ambient temperature (Ta) fluctuations, especially in spring or in northern latitudes, could ...

Narrow band gap amorphous silicon semiconductors

DOEpatents

Madan, A.; Mahan, A.H.

1985-01-10

Disclosed is a narrow band gap amorphous silicon semiconductor comprising an alloy of amorphous silicon and a band gap narrowing element selected from the group consisting of Sn, Ge, and Pb, with an electron donor dopant selected from the group consisting of P, As, Sb, Bi and N. The process for producing the narrow band gap amorphous silicon semiconductor comprises the steps of forming an alloy comprising amorphous silicon and at least one of the aforesaid band gap narrowing elements in amount sufficient to narrow the band gap of the silicon semiconductor alloy below that of amorphous silicon, and also utilizing sufficient amounts of the aforesaid electron donor dopant to maintain the amorphous silicon alloy as an n-type semiconductor.

BERKELEY LAB WINDOW

DOE Office of Scientific and Technical Information (OSTI.GOV)

Curcija, Dragan Charlie; Zhu, Ling; Czarnecki, Stephen

WINDOW features include: - Microsoft Windows TM interface - algorithms for the calculation of total fenestration product U-values and Solar Heat Gain Coefficient consistent with ASHRAE SPC 142, ISO 15099, and the National Fenestration Rating Council - a Condensation Resistance Index in accordance with the NFRC 500 Standard - and integrated database of properties - imports data from other LBNL window analysis software: - Import THERM file into the Frame Library - Import records from IGDB and OPtics5 into the Glass Library for the optical properties of coated and uncoated glazings, laminates, and applied films. Program Capabilities WINDOW 7.2 offersmore » the following features: The ability to analyze products made from any combination of glazing layers, gas layers, frames, spacers, and dividers under any environmental conditions and at any tilt; The ability to model complex glazing systems such as venetian blinds and roller shades. Directly accessible libraries of window system components, (glazing systems, glazing layers, gas fills, frame and divider elements), and environmental conditions; The choice of working in English (IP), or Systeme International (SI) units; The ability to specify the dimensions and thermal properties of each frame element (header, sills, jamb, mullion) in a window; A multi-band (wavelength-by-wavelength) spectral model; A Glass Library which can access spectral data files for many common glazing materials from the Optics5database; A night-sky radiative model; A link with the DOE-2.1E and Energy Plus building energy analysis program. Performance Indices and Other Results For a user-defined fenestration system and user-defined environmental conditions, WINDOW calculates: The U-value, solar heat gain coefficient, shading coefficient, and visible transmittance for the complete window system; The U-value, solar heat gain coefficient, shading coefficient, and visible transmittance for the glazing system (center-of-glass values); The U-values of

A shot through the window.

PubMed

Burnett, B R

2001-03-01

At issue in this case was whether an unusual window defect seen in two of the crime scene photographs was due to a bullet and if so, if that same bullet fatally wounded the victim. The window appeared to have been cracked prior to the apparent shot through it. A .22 bullet recovered from autopsy, when examined only by light microscopy, failed to show associated glass fragments. A previously cracked test window was shot a number of times with .22 caliber bullets near the cracks in an effort to simulate the window defect seen in the crime scene photographs. Several of the defects produced by the test window shots appeared similar to the crime scene window defect. The .22 bullet taken from the victim and several of the test bullets (collected by a cotton box) were examined by scanning electron microscopy/energy dispersive X-ray spectroscopy. The test bullets showed glass particles on and embedded in their surfaces. Particles of similar size and composition were found embedded in the surface of the bullet from the victim. The bullet likely struck the window prior to hitting the victim. It was apparent by the morphology of some of the mushroomed test .22 bullets that they hit the window crack. These bullets showed that the glass on one side of a crack often fails before the other side during the strike. Aggregations of powdered glass on many of the mushroomed surfaces of the .22 bullets suggest that as the bullet mushrooms during impact on the window surface, the glass in contact with the bullet powderizes and coats the mushroomed surface of the bullet with a layer of fine glass particles.

Hybrid window layer for photovoltaic cells

DOEpatents

Deng, Xunming

2010-02-23

A novel photovoltaic solar cell and method of making the same are disclosed. The solar cell includes: at least one absorber layer which could either be a lightly doped layer or an undoped layer, and at least a doped window-layers which comprise at least two sub-window-layers. The first sub-window-layer, which is next to the absorber-layer, is deposited to form desirable junction with the absorber-layer. The second sub-window-layer, which is next to the first sub-window-layer, but not in direct contact with the absorber-layer, is deposited in order to have transmission higher than the first-sub-window-layer.

Hybrid window layer for photovoltaic cells

DOEpatents

Deng, Xunming [Syvania, OH; Liao, Xianbo [Toledo, OH; Du, Wenhui [Toledo, OH

2011-10-04

A novel photovoltaic solar cell and method of making the same are disclosed. The solar cell includes: at least one absorber layer which could either be a lightly doped layer or an undoped layer, and at least a doped window-layers which comprise at least two sub-window-layers. The first sub-window-layer, which is next to the absorber-layer, is deposited to form desirable junction with the absorber-layer. The second sub-window-layer, which is next to the first sub-window-layer, but not in direct contact with the absorber-layer, is deposited in order to have transmission higher than the first-sub-window-layer.

Hybrid window layer for photovoltaic cells

DOEpatents

Deng, Xunming [Sylvania, OH; Liao, Xianbo [Toledo, OH; Du, Wenhui [Toledo, OH

2011-02-01

A novel photovoltaic solar cell and method of making the same are disclosed. The solar cell includes: at least one absorber layer which could either be a lightly doped layer or an undoped layer, and at least a doped window-layers which comprise at least two sub-window-layers. The first sub-window-layer, which is next to the absorber-layer, is deposited to form desirable junction with the absorber-layer. The second sub-window-layer, which is next to the first sub-window-layer, but not in direct contact with the absorber-layer, is deposited in order to have transmission higher than the first-sub-window-layer.

National Fenestration Rating Council (NFRC) | Efficient Windows

Science.gov Websites

Collaborative Foundry Foundry New Construction Windows Window Selection Tool Selection Process Design Guidance Installation Replacement Windows Window Selection Tool Assessing Options Selection Process Design Guidance Installation Understanding Windows Benefits Design Considerations Measuring

U-Factor (U-value) | Efficient Windows Collaborative

Science.gov Websites

Foundry Foundry New Construction Windows Window Selection Tool Selection Process Design Guidance Installation Replacement Windows Window Selection Tool Assessing Options Selection Process Design Guidance Installation Understanding Windows Benefits Design Considerations Measuring Performance Performance Standards

Changes in mammary histology and transcriptome profiles by low-dose exposure to environmental phenols at critical windows of development.

PubMed

Gopalakrishnan, Kalpana; Teitelbaum, Susan L; Lambertini, Luca; Wetmur, James; Manservisi, Fabiana; Falcioni, Laura; Panzacchi, Simona; Belpoggi, Fiorella; Chen, Jia

2017-01-01

Exposure to environmental chemicals has been linked to altered mammary development and cancer risk at high doses using animal models. Effects at low doses comparable to human exposure remain poorly understood, especially during critical developmental windows. We investigated the effects of two environmental phenols commonly used in personal care products - methyl paraben (MPB) and triclosan (TCS) - on the histology and transcriptome of normal mammary glands at low doses mimicking human exposure during critical windows of development. Sprague-Dawley rats were exposed during perinatal, prepubertal and pubertal windows, as well as from birth to lactation. Low-dose exposure to MPB and TCS induced measurable changes in both mammary histology (by Masson's Trichrome Stain) and transcriptome (by microarrays) in a window-specific fashion. Puberty represented a window of heightened sensitivity to MPB, with increased glandular tissue and changes of expression in 295 genes with significant enrichment in functions such as DNA replication and cell cycle regulation. Long-term exposure to TCS from birth to lactation was associated with increased adipose and reduced glandular and secretory tissue, with expression alterations in 993 genes enriched in pathways such as cholesterol synthesis and adipogenesis. Finally, enrichment analyses revealed that genes modified by MPB and TCS were over-represented in human breast cancer gene signatures, suggesting possible links with breast carcinogenesis. These findings highlight the issues of critical windows of susceptibility that may confer heightened sensitivity to environmental insults and implicate the potential health effects of these ubiquitous environmental chemicals in breast cancer. Copyright © 2016 Elsevier Inc. All rights reserved.

Concurrent validity of the Microsoft Kinect for Windows v2 for measuring spatiotemporal gait parameters.

PubMed

Dolatabadi, Elham; Taati, Babak; Mihailidis, Alex

2016-09-01

This paper presents a study to evaluate the concurrent validity of the Microsoft Kinect for Windows v2 for measuring the spatiotemporal parameters of gait. Twenty healthy adults performed several sequences of walks across a GAITRite mat under three different conditions: usual pace, fast pace, and dual task. Each walking sequence was simultaneously captured with two Kinect for Windows v2 and the GAITRite system. An automated algorithm was employed to extract various spatiotemporal features including stance time, step length, step time and gait velocity from the recorded Kinect v2 sequences. Accuracy in terms of reliability, concurrent validity and limits of agreement was examined for each gait feature under different walking conditions. The 95% Bland-Altman limits of agreement were narrow enough for the Kinect v2 to be a valid tool for measuring all reported spatiotemporal parameters of gait in all three conditions. An excellent intraclass correlation coefficient (ICC2, 1) ranging from 0.9 to 0.98 was observed for all gait measures across different walking conditions. The inter trial reliability of all gait parameters were shown to be strong for all walking types (ICC3, 1 > 0.73). The results of this study suggest that the Kinect for Windows v2 has the capacity to measure selected spatiotemporal gait parameters for healthy adults. Copyright © 2016 IPEM. Published by Elsevier Ltd. All rights reserved.

The Efficient Windows Collaborative

DOE Office of Scientific and Technical Information (OSTI.GOV)

Petermann, Nils

2006-03-31

The Efficient Windows Collaborative (EWC) is a coalition of manufacturers, component suppliers, government agencies, research institutions, and others who partner to expand the market for energy efficient window products. Funded through a cooperative agreement with the U.S. Department of Energy, the EWC provides education, communication and outreach in order to transform the residential window market to 70% energy efficient products by 2005. Implementation of the EWC is managed by the Alliance to Save Energy, with support from the University of Minnesota and Lawrence Berkeley National Laboratory.

Challenger Center's Window on the Universe

NASA Astrophysics Data System (ADS)

Livengood, T. A.; Goldstein, J. J.; Smith, S.; Bobrowsky, M.; Radnofsky, M.; Perelmuter, J.-M.; Jaggar, L.

2001-11-01

Challenger Center for Space Science Education's Window on the Universe program aims to create a network of under-served communities across the nation dedicated to sustained science, math, and technology education. Window communities presently include Broken Arrow, OK; Muncie, IN; Moscow, ID; Nogales, AZ; Tuskegee, AL; Marquette, MI; Altamont, KS; Washington, D.C.; and other emerging sites. Window uses themes of human space flight and the space sciences as interdisciplinary means to inspire entire communities. Practicing scientists and engineers engaged in these disciplines are invited to volunteer to become a part of these communities for a week, each visitor reaching roughly 2000 K-12 students through individual classroom visits and Family Science Night events during an intense Window on the Universe Week. In the same Window Week, Challenger Center scientists and educators present a workshop for local educators to provide training in the use of a K-12 educational module built around a particular space science and exploration theme. Window communities follow a 3-year development: Year 1, join the network, experience Window Week presented by Challenger Center and visiting researchers; Year 2, same as Year 1 plus workshop on partnering with local organizations to develop sources of visiting researchers and to enhance connections with local resources; Year 3 and subsequent, the community stages its own Window Week, with Challenger Center providing new education modules and training workshops for "master educators" from the Window community, after which the master educators return home to conduct training workshops of their own. Challenger Center remains a resource and clearinghouse for Window communities to acquire experience, technical information, and opportunities for distance collaboration with other Window communities. Window on the Universe is dedicated to assessing degree of success vs. failure in each program component and as a whole, using pre- and post

Neural correlates of perceptual narrowing in cross-species face-voice matching.

PubMed

Grossmann, Tobias; Missana, Manuela; Friederici, Angela D; Ghazanfar, Asif A

2012-11-01

Integrating the multisensory features of talking faces is critical to learning and extracting coherent meaning from social signals. While we know much about the development of these capacities at the behavioral level, we know very little about the underlying neural processes. One prominent behavioral milestone of these capacities is the perceptual narrowing of face-voice matching, whereby young infants match faces and voices across species, but older infants do not. In the present study, we provide neurophysiological evidence for developmental decline in cross-species face-voice matching. We measured event-related brain potentials (ERPs) while 4- and 8-month-old infants watched and listened to congruent and incongruent audio-visual presentations of monkey vocalizations and humans mimicking monkey vocalizations. The ERP results indicated that younger infants distinguished between the congruent and the incongruent faces and voices regardless of species, whereas in older infants, the sensitivity to multisensory congruency was limited to the human face and voice. Furthermore, with development, visual and frontal brain processes and their functional connectivity became more sensitive to the congruence of human faces and voices relative to monkey faces and voices. Our data show the neural correlates of perceptual narrowing in face-voice matching and support the notion that postnatal experience with species identity is associated with neural changes in multisensory processing (Lewkowicz & Ghazanfar, 2009). © 2012 Blackwell Publishing Ltd.

16 CFR 455.3 - Window form.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Window form. 455.3 Section 455.3 Commercial... Window form. (a) Form given to buyer. Give the buyer of a used vehicle sold by you the window form...) Incorporated into contract. The information on the final version of the window form is incorporated into the...

Composition of 12-18 th century window glass in Belgium: Non-figurative windows in secular buildings and stained-glass windows in religious buildings

NASA Astrophysics Data System (ADS)

Schalm, Olivier; Janssens, Koen; Wouters, Hilde; Caluwé, Danielle

2007-07-01

A set of ca. 500 window glass fragments originating from different historical sites in Belgium and covering the period 12 th-18 th century was analyzed by means of electron probe microanalysis. Most samples are archaeological finds deriving from non-figurative windows in secular buildings. However, the analyzed set also contains glass sampled from still existing non-figurative windows in secular buildings and stained-glass windows in religious buildings. A sudden compositional change at the end of the 14 th century can be noticed among the series of glass compositions that were obtained. These changes could be related to the use of different glassmaker recipes and to the introduction of new raw materials for glass making.

High performance sapphire windows

NASA Technical Reports Server (NTRS)

Bates, Stephen C.; Liou, Larry

1993-01-01

High-quality, wide-aperture optical access is usually required for the advanced laser diagnostics that can now make a wide variety of non-intrusive measurements of combustion processes. Specially processed and mounted sapphire windows are proposed to provide this optical access to extreme environment. Through surface treatments and proper thermal stress design, single crystal sapphire can be a mechanically equivalent replacement for high strength steel. A prototype sapphire window and mounting system have been developed in a successful NASA SBIR Phase 1 project. A large and reliable increase in sapphire design strength (as much as 10x) has been achieved, and the initial specifications necessary for these gains have been defined. Failure testing of small windows has conclusively demonstrated the increased sapphire strength, indicating that a nearly flawless surface polish is the primary cause of strengthening, while an unusual mounting arrangement also significantly contributes to a larger effective strength. Phase 2 work will complete specification and demonstration of these windows, and will fabricate a set for use at NASA. The enhanced capabilities of these high performance sapphire windows will lead to many diagnostic capabilities not previously possible, as well as new applications for sapphire.

High performance sapphire windows

NASA Astrophysics Data System (ADS)

Bates, Stephen C.; Liou, Larry

1993-02-01

High-quality, wide-aperture optical access is usually required for the advanced laser diagnostics that can now make a wide variety of non-intrusive measurements of combustion processes. Specially processed and mounted sapphire windows are proposed to provide this optical access to extreme environment. Through surface treatments and proper thermal stress design, single crystal sapphire can be a mechanically equivalent replacement for high strength steel. A prototype sapphire window and mounting system have been developed in a successful NASA SBIR Phase 1 project. A large and reliable increase in sapphire design strength (as much as 10x) has been achieved, and the initial specifications necessary for these gains have been defined. Failure testing of small windows has conclusively demonstrated the increased sapphire strength, indicating that a nearly flawless surface polish is the primary cause of strengthening, while an unusual mounting arrangement also significantly contributes to a larger effective strength. Phase 2 work will complete specification and demonstration of these windows, and will fabricate a set for use at NASA. The enhanced capabilities of these high performance sapphire windows will lead to many diagnostic capabilities not previously possible, as well as new applications for sapphire.

A developmental-psychobiological approach to developmental neuropsychology.

PubMed

Michel, G F

2001-01-01

Although both developmental psychobiology and developmental neuropsychology examine the interface between biological and psychological processes, they differ in conceptual framework. This article argues for the incorporation into developmental neuropsychology of certain aspects of the conceptual framework of developmental psychobiology. Three principles of dynamic psychobiological interaction are described and applied to four issues in neuropsychology (handedness, sex differences in behavior, critical periods, and modularity of structure-function relations). Then, it is proposed that developmental psychobiology can make four direct contributions to developmental neuropsychology. Finally, it is argued that the value of the conceptual framework provided by developmental psychobiology depends, in part, on how well it translates into procedures that can be applied in the clinical settings of the developmental neuropsychologist.

Window Observational Research Facility (WORF)

NASA Technical Reports Server (NTRS)

Pelfrey, Joseph; Sledd, Annette

2007-01-01

This viewgraph document concerns the Window Observational Research Facility (WORF) Rack, a unique facility designed for use with the US Lab Destiny Module window. WORF will provide valuable resources for Earth Science payloads along with serving the purpose of protecting the lab window. The facility can be used for remote sensing instrumentation test and validation in a shirt sleeve environment. WORF will also provide a training platform for crewmembers to do orbital observations of other planetary bodies. WORF payloads will be able to conduct terrestrial studies utilizing the data collected from utilizing WORF and the lab window.

Phelan-McDermid syndrome presenting with developmental delays and facial dysmorphisms.

PubMed

Kim, Yoon-Myung; Choi, In-Hee; Kim, Jun Suk; Kim, Ja Hye; Cho, Ja Hyang; Lee, Beom Hee; Kim, Gu-Hwan; Choi, Jin-Ho; Seo, Eul-Ju; Yoo, Han-Wook

2016-11-01

Phelan-McDermid syndrome is a rare genetic disorder caused by the terminal or interstitial deletion of the chromosome 22q13.3. Patients with this syndrome usually have global developmental delay, hypotonia, and speech delays. Several putative genes such as the SHANK3 , RAB , RABL2B , and IB2 are responsible for the neurological features. This study describes the clinical features and outcomes of Korean patients with Phelan-McDermid syndrome. Two patients showing global developmental delay, hypotonia, and speech delay were diagnosed with Phelan-McDermid syndrome via chromosome analysis, fluorescent in situ hybridization, and multiplex ligation-dependent probe amplification analysis. Brain magnetic resonance imaging of Patients 1 and 2 showed delayed myelination and severe communicating hydrocephalus, respectively. Electroencephalography in patient 2 showed high amplitude spike discharges from the left frontotemporoparietal area, but neither patient developed seizures. Kidney ultrasonography of both the patients revealed multicystic kidney disease and pelviectasis, respectively. Patient 2 experienced recurrent respiratory infections, and chest computed tomography findings demonstrated laryngotracheomalacia and bronchial narrowing. He subsequently died because of heart failure after a ventriculoperitoneal shunt operation at 5 months of age. Patient 1, who is currently 20 months old, has been undergoing rehabilitation therapy. However, global developmental delay was noted, as determines using the Korean Infant and Child Development test, the Denver developmental test, and the Bayley developmental test. This report describes the clinical features, outcomes, and molecular genetic characteristics of two Korean patients with Phelan-McDermid syndrome.

Present and future of developmental neuropsychopharmacology.

PubMed

Arango, Celso

2015-05-01

The field of child and adolescent psychiatry has always lagged behind adult psychiatry. With recent evidence that the vast majority of mental disorders, even when they emerge in adulthood, cause abnormal neurodevelopment and resultant emphasis on prevention and early intervention, there is a need to put child psychiatry at the top of the agenda in mental health research. This should also be the case for developmental neuropsychopharmacology. The target of drug discovery should shift toward a population younger than the one that is typically included in clinical trials. This is not only a matter of trying to replicate what has been found in individuals with mature brains; it is about searching for new strategies that address developing brains while the therapeutic window for their effect is still open. At present, major concerns in developmental psychopharmacology are over-prescription rates and use of psychotropic medications for conditions with a particularly underdeveloped evidence base, as well as adverse effects, especially potentially life-shortening cardiometabolic effects and suicidal ideation. The future of research in this area should focus on the use of drugs for primary and secondary prevention that would modify abnormal brain development. Copyright © 2014 Elsevier B.V. and ECNP. All rights reserved.

Rigid thin windows for vacuum applications

DOEpatents

Meyer, Glenn Allyn; Ciarlo, Dino R.; Myers, Booth Richard; Chen, Hao-Lin; Wakalopulos, George

1999-01-01

A thin window that stands off atmospheric pressure is fabricated using photolithographic and wet chemical etching techniques and comprises at least two layers: an etch stop layer and a protective barrier layer. The window structure also comprises a series of support ribs running the width of the window. The windows are typically made of boron-doped silicon and silicon nitride and are useful in instruments such as electron beam guns and x-ray detectors. In an electron beam gun, the window does not impede the electrons and has demonstrated outstanding gun performance and survivability during the gun tube manufacturing process.

High-Reliability Waveguide Vacuum/Pressure Window

NASA Technical Reports Server (NTRS)

Britcliffe, Michael J.; Hanson, Theodore R.; Long, Ezra M.; Montanez, Steven

2013-01-01

The NASA Deep Space Network (DSN) uses commercial waveguide windows on the output waveguide of Ka-band (32 GHz) low-noise amplifiers. Mechanical failure of these windows resulted in an unacceptable loss in tracking time. To address this issue, a new Ka-band WR-28 waveguide window has been designed, fabricated, and tested. The window uses a slab of low-loss, low-dielectric constant foam that is bonded into a 1/2-wave-thick waveguide/flange. The foam is a commercially available, rigid, closed-cell polymethacrylimide. It has excellent electrical properties with a dielectric constant of 1.04, and a loss tangent of 0.01. It is relatively strong with a tensile strength of 1 MPa. The material is virtually impermeable to helium. The finished window exhibits a leak rate of less than 3x10(exp -3)cu cm/s with helium. The material is also chemically resistant and can be cleaned with acetone. The window is constructed by fabricating a window body by brazing a short length of WR-28 copper waveguide into a standard rectangular flange, and machining the resulting part to a thickness of 4.6 mm. The foam is machined to a rectangular shape with a dimension of 7.06x3.53 mm. The foam is bonded into the body with a two-part epoxy. After curing, the excess glue and foam are knife-trimmed by hand. The finished window has a loss of less than 0.08 dB (2%) and a return loss of greater than 25 dB at 32 GHz. This meets the requirements for the DSN application. The window is usable for most applications over the entire 26-to-40-GHz waveguide band. The window return loss can be tuned to a required frequency by var y in g the thickness of the window slightly. Most standard waveguide windows use a thin membrane of material bonded into a recess in a waveguide flange, or sandwiched between two flanges with a polymer seal. Designs using the recessed window are prone to mechanical failure over time due to constraints on the dimensions of the recess that allow the bond to fail. Designs using the

Changes in Mammary Histology and Transcriptome Profiles by Low-Dose Exposure to Environmental Phenols at Critical Windows of Development1

PubMed Central

Gopalakrishnan, Kalpana; Teitelbaum, Susan L.; Lambertini, Luca; Wetmur, James; Manservisi, Fabiana; Falcioni, Laura; Panzacchi, Simona; Belpoggi, Fiorella; Chen, Jia

2016-01-01

Exposure to environmental chemicals has been linked to altered mammary development and cancer risk at high doses using animal models. Effects at low doses comparable to human exposure remain poorly understood, especially during critical developmental windows. We investigated the effects of two environmental phenols commonly used in personal care products – methyl paraben (MPB) and triclosan (TCS) – on the histology and transcriptome of normal mammary glands at low doses mimicking human exposure during critical windows of development. Sprague-Dawley rats were exposed during perinatal, prepubertal and pubertal windows, as well as from birth to lactation. Low-dose exposure to MPB and TCS induced measurable changes in both mammary histology (by Masson’s Trichrome Stain) and transcriptome (by microarrays) in a window-specific fashion. Puberty represented a window of heightened sensitivity to MPB, with increased glandular tissue and changes of expression in 295 genes with significant enrichment in functions such as DNA replication and cell cycle regulation. Long-term exposure to TCS from birth to lactation was associated with increased adipose and reduced glandular and secretory tissue, with expression alterations in 993 genes enriched in pathways such as cholesterol synthesis and adipogenesis. Finally, enrichment analyses revealed that genes modified by MPB and TCS were over-represented in human breast cancer gene signatures, suggesting possible links with breast carcinogenesis. These findings highlight the issues of critical windows of susceptibility that may confer heightened sensitivity to environmental insults and implicate the potential health effects of these ubiquitous environmental chemicals in breast cancer. PMID:27810681

Model MTF for the mosaic window

NASA Astrophysics Data System (ADS)

Xing, Zhenchong; Hong, Yongfeng; Zhang, Bao

2017-10-01

An electro-optical targeting system mounted either within an airframe or housed in separate pods requires a window to form an environmental barrier to the outside world. In current practice, such windows usually use a mosaic or segmented window. When scanning the target, internally gimbaled systems sweep over the window, which can affect the modulation transfer function (MTF) due to wave-front division and optical path differences arising from the thickness/wedge differences between panes. In this paper, a mathematical model of the MTF of the mosaic window is presented that allows an analysis of influencing factors; we show how the model may be integrated into ZEMAX® software for optical design. The model can be used to guide both the design and the tolerance analysis of optical systems that employ a mosaic window.

Orion Hatch Window Testing

NASA Image and Video Library

2018-04-09

Mark Nurge, Ph.D., a physicist in the Applied Physics Lab with the Exploration Research and Technology Programs at NASA's Kennedy Space Center in Florida, looks at data during the first optical quality test on a full window stack that is ready for installation in the docking hatch of NASA's Orion spacecraft. The data from the tests will help improve the requirements for manufacturing tolerances on Orion's windows and verify how the window should perform in space. Orion is being prepared for its first integrated uncrewed flight atop NASA's Space Launch System rocket on Exploration Mission-1.

AN ASSESSMENT OF MCNP WEIGHT WINDOWS

DOE Office of Scientific and Technical Information (OSTI.GOV)

J. S. HENDRICKS; C. N. CULBERTSON

2000-01-01

The weight window variance reduction method in the general-purpose Monte Carlo N-Particle radiation transport code MCNPTM has recently been rewritten. In particular, it is now possible to generate weight window importance functions on a superimposed mesh, eliminating the need to subdivide geometries for variance reduction purposes. Our assessment addresses the following questions: (1) Does the new MCNP4C treatment utilize weight windows as well as the former MCNP4B treatment? (2) Does the new MCNP4C weight window generator generate importance functions as well as MCNP4B? (3) How do superimposed mesh weight windows compare to cell-based weight windows? (4) What are the shortcomingsmore » of the new MCNP4C weight window generator? Our assessment was carried out with five neutron and photon shielding problems chosen for their demanding variance reduction requirements. The problems were an oil well logging problem, the Oak Ridge fusion shielding benchmark problem, a photon skyshine problem, an air-over-ground problem, and a sample problem for variance reduction.« less

Least Squares Moving-Window Spectral Analysis.

PubMed

Lee, Young Jong

2017-08-01

Least squares regression is proposed as a moving-windows method for analysis of a series of spectra acquired as a function of external perturbation. The least squares moving-window (LSMW) method can be considered an extended form of the Savitzky-Golay differentiation for nonuniform perturbation spacing. LSMW is characterized in terms of moving-window size, perturbation spacing type, and intensity noise. Simulation results from LSMW are compared with results from other numerical differentiation methods, such as single-interval differentiation, autocorrelation moving-window, and perturbation correlation moving-window methods. It is demonstrated that this simple LSMW method can be useful for quantitative analysis of nonuniformly spaced spectral data with high frequency noise.

Superconductive radiofrequency window assembly

DOEpatents

Phillips, Harry Lawrence; Elliott, Thomas S.

1998-01-01

The present invention is a superconducting radiofrequency window assembly for use in an electron beam accelerator. The srf window assembly (20) has a superconducting metal-ceramic design. The srf window assembly (20) comprises a superconducting frame (30), a ceramic plate (40) having a superconducting metallized area, and a superconducting eyelet (50) for sealing plate (40) into frame (30). The plate (40) is brazed to eyelet (50) which is then electron beam welded to frame (30). A method for providing a ceramic object mounted in a metal member to withstand cryogenic temperatures is also provided. The method involves a new metallization process for coating a selected area of a ceramic object with a thin film of a superconducting material. Finally, a method for assembling an electron beam accelerator cavity utilizing the srf window assembly is provided. The procedure is carried out within an ultra clean room to minimize exposure to particulates which adversely affect the performance of the cavity within the electron beam accelerator.

Superconductive radiofrequency window assembly

DOEpatents

Phillips, H.L.; Elliott, T.S.

1998-05-19

The present invention is a superconducting radiofrequency window assembly for use in an electron beam accelerator. The SRF window assembly has a superconducting metal-ceramic design. The SRF window assembly comprises a superconducting frame, a ceramic plate having a superconducting metallized area, and a superconducting eyelet for sealing plate into frame. The plate is brazed to eyelet which is then electron beam welded to frame. A method for providing a ceramic object mounted in a metal member to withstand cryogenic temperatures is also provided. The method involves a new metallization process for coating a selected area of a ceramic object with a thin film of a superconducting material. Finally, a method for assembling an electron beam accelerator cavity utilizing the SRF window assembly is provided. The procedure is carried out within an ultra clean room to minimize exposure to particulates which adversely affect the performance of the cavity within the electron beam accelerator. 11 figs.

Superconducting radiofrequency window assembly

DOEpatents

Phillips, Harry L.; Elliott, Thomas S.

1997-01-01

The present invention is a superconducting radiofrequency window assembly for use in an electron beam accelerator. The srf window assembly (20) has a superconducting metal-ceramic design. The srf window assembly (20) comprises a superconducting frame (30), a ceramic plate (40) having a superconducting metallized area, and a superconducting eyelet (50) for sealing plate (40) into frame (30). The plate (40) is brazed to eyelet (50) which is then electron beam welded to frame (30). A method for providing a ceramic object mounted in a metal member to withstand cryogenic temperatures is also provided. The method involves a new metallization process for coating a selected area of a ceramic object with a thin film of a superconducting material. Finally, a method for assembling an electron beam accelerator cavity utilizing the srf window assembly is provided. The procedure is carried out within an ultra clean room to minimize exposure to particulates which adversely affect the performance of the cavity within the electron beam accelerator.

Superconducting radiofrequency window assembly

DOEpatents

Phillips, H.L.; Elliott, T.S.

1997-03-11

The present invention is a superconducting radiofrequency window assembly for use in an electron beam accelerator. The srf window assembly has a superconducting metal-ceramic design. The srf window assembly comprises a superconducting frame, a ceramic plate having a superconducting metallized area, and a superconducting eyelet for sealing plate into frame. The plate is brazed to eyelet which is then electron beam welded to frame. A method for providing a ceramic object mounted in a metal member to withstand cryogenic temperatures is also provided. The method involves a new metallization process for coating a selected area of a ceramic object with a thin film of a superconducting material. Finally, a method for assembling an electron beam accelerator cavity utilizing the srf window assembly is provided. The procedure is carried out within an ultra clean room to minimize exposure to particulates which adversely affect the performance of the cavity within the electron beam accelerator. 11 figs.

Effects of mixing eggs of different initial incubation time on the hatching pattern, chick embryonic development and post-hatch performance.

PubMed

Zhong, Zhentao; Yu, Yue; Jin, Shufang; Pan, Jinming

2018-01-01

The hatch window that varies from 24 to 48 h is known to influence post-hatch performance of chicks. A narrow hatch window is needed for commercial poultry industry to acquire a high level of uniformity of chick quality. Hatching synchronization observed in avian species presents possibilities in altering hatch window in artificial incubation. Layer eggs which were laid on the same day by a single breeder flock and stored for no more than two days started incubation 12 h apart to obtain developmental distinction. The eggs of different initial incubation time were mixed as rows adjacent to rows on day 12 of incubation. During the hatching period (since day 18), hatching time of individual eggs and hatch window were obtained by video recordings. Embryonic development (day 18 and 20) and post-hatch performance up to day 7 were measured. The manipulation of mixing eggs of different initial incubation time shortened the hatch window of late incubated eggs in the manipulated group by delaying the onset of hatching process, and improved the hatchability. Compared to the control groups, chick embryos or chicks in the egg redistribution group showed no significant difference in embryonic development and post-hatch performance up to day 7. We have demonstrated that eggs that were incubated with advanced eggs performed a narrow spread of hatch with higher hatchability, normal embryonic development as well as unaffected chick quality. This specific manipulation is applicable in industrial poultry production to shorten hatch window and improve the uniformity of chick quality.

X-Windows Socket Widget Class

NASA Technical Reports Server (NTRS)

Barry, Matthew R.

2006-01-01

The X-Windows Socket Widget Class ("Class" is used here in the object-oriented-programming sense of the word) was devised to simplify the task of implementing network connections for graphical-user-interface (GUI) computer programs. UNIX Transmission Control Protocol/Internet Protocol (TCP/IP) socket programming libraries require many method calls to configure, operate, and destroy sockets. Most X Windows GUI programs use widget sets or toolkits to facilitate management of complex objects. The widget standards facilitate construction of toolkits and application programs. The X-Windows Socket Widget Class encapsulates UNIX TCP/IP socket-management tasks within the framework of an X Windows widget. Using the widget framework, X Windows GUI programs can treat one or more network socket instances in the same manner as that of other graphical widgets, making it easier to program sockets. Wrapping ISP socket programming libraries inside a widget framework enables a programmer to treat a network interface as though it were a GUI.

Identifying Stable Reference Genes for qRT-PCR Normalisation in Gene Expression Studies of Narrow-Leafed Lupin (Lupinus angustifolius L.).

PubMed

Taylor, Candy M; Jost, Ricarda; Erskine, William; Nelson, Matthew N

2016-01-01

Quantitative Reverse Transcription PCR (qRT-PCR) is currently one of the most popular, high-throughput and sensitive technologies available for quantifying gene expression. Its accurate application depends heavily upon normalisation of gene-of-interest data with reference genes that are uniformly expressed under experimental conditions. The aim of this study was to provide the first validation of reference genes for Lupinus angustifolius (narrow-leafed lupin, a significant grain legume crop) using a selection of seven genes previously trialed as reference genes for the model legume, Medicago truncatula. In a preliminary evaluation, the seven candidate reference genes were assessed on the basis of primer specificity for their respective targeted region, PCR amplification efficiency, and ability to discriminate between cDNA and gDNA. Following this assessment, expression of the three most promising candidates [Ubiquitin C (UBC), Helicase (HEL), and Polypyrimidine tract-binding protein (PTB)] was evaluated using the NormFinder and RefFinder statistical algorithms in two narrow-leafed lupin lines, both with and without vernalisation treatment, and across seven organ types (cotyledons, stem, leaves, shoot apical meristem, flowers, pods and roots) encompassing three developmental stages. UBC was consistently identified as the most stable candidate and has sufficiently uniform expression that it may be used as a sole reference gene under the experimental conditions tested here. However, as organ type and developmental stage were associated with greater variability in relative expression, it is recommended using UBC and HEL as a pair to achieve optimal normalisation. These results highlight the importance of rigorously assessing candidate reference genes for each species across a diverse range of organs and developmental stages. With emerging technologies, such as RNAseq, and the completion of valuable transcriptome data sets, it is possible that other potentially more

Identifying Stable Reference Genes for qRT-PCR Normalisation in Gene Expression Studies of Narrow-Leafed Lupin (Lupinus angustifolius L.)

PubMed Central

Erskine, William; Nelson, Matthew N.

2016-01-01

Quantitative Reverse Transcription PCR (qRT-PCR) is currently one of the most popular, high-throughput and sensitive technologies available for quantifying gene expression. Its accurate application depends heavily upon normalisation of gene-of-interest data with reference genes that are uniformly expressed under experimental conditions. The aim of this study was to provide the first validation of reference genes for Lupinus angustifolius (narrow-leafed lupin, a significant grain legume crop) using a selection of seven genes previously trialed as reference genes for the model legume, Medicago truncatula. In a preliminary evaluation, the seven candidate reference genes were assessed on the basis of primer specificity for their respective targeted region, PCR amplification efficiency, and ability to discriminate between cDNA and gDNA. Following this assessment, expression of the three most promising candidates [Ubiquitin C (UBC), Helicase (HEL), and Polypyrimidine tract-binding protein (PTB)] was evaluated using the NormFinder and RefFinder statistical algorithms in two narrow-leafed lupin lines, both with and without vernalisation treatment, and across seven organ types (cotyledons, stem, leaves, shoot apical meristem, flowers, pods and roots) encompassing three developmental stages. UBC was consistently identified as the most stable candidate and has sufficiently uniform expression that it may be used as a sole reference gene under the experimental conditions tested here. However, as organ type and developmental stage were associated with greater variability in relative expression, it is recommended using UBC and HEL as a pair to achieve optimal normalisation. These results highlight the importance of rigorously assessing candidate reference genes for each species across a diverse range of organs and developmental stages. With emerging technologies, such as RNAseq, and the completion of valuable transcriptome data sets, it is possible that other potentially more

Orion Hatch Window Testing

NASA Image and Video Library

2018-04-09

The first optical quality testing on a full window stack that is ready for installation in the docking hatch of NASA's Orion spacecraft is underway inside a laboratory in the Neil Armstrong Operations and Checkout Building at the agency's Kennedy Space Center in Florida. The test is being performed by a team from the center's Exploration Research and Technology Programs. The data from the tests will help improve the requirements for manufacturing tolerances on Orion's windows and verify how the window should perform in space. Orion is being prepared for its first integrated uncrewed flight atop NASA's Space Launch System rocket on Exploration Mission-1.

Imaging windows for long-term intravital imaging

PubMed Central

Alieva, Maria; Ritsma, Laila; Giedt, Randy J; Weissleder, Ralph; van Rheenen, Jacco

2014-01-01

Intravital microscopy is increasingly used to visualize and quantitate dynamic biological processes at the (sub)cellular level in live animals. By visualizing tissues through imaging windows, individual cells (e.g., cancer, host, or stem cells) can be tracked and studied over a time-span of days to months. Several imaging windows have been developed to access tissues including the brain, superficial fascia, mammary glands, liver, kidney, pancreas, and small intestine among others. Here, we review the development of imaging windows and compare the most commonly used long-term imaging windows for cancer biology: the cranial imaging window, the dorsal skin fold chamber, the mammary imaging window, and the abdominal imaging window. Moreover, we provide technical details, considerations, and trouble-shooting tips on the surgical procedures and microscopy setups for each imaging window and explain different strategies to assure imaging of the same area over multiple imaging sessions. This review aims to be a useful resource for establishing the long-term intravital imaging procedure. PMID:28243510

Solar Heat Gain Coefficient (SHGC) | Efficient Windows Collaborative

Science.gov Websites

Foundry Foundry New Construction Windows Window Selection Tool Selection Process Design Guidance Installation Replacement Windows Window Selection Tool Assessing Options Selection Process Design Guidance Installation Understanding Windows Benefits Design Considerations Measuring Performance Performance Standards

Photorefractive-based adaptive optical windows

NASA Astrophysics Data System (ADS)

Liu, Yuexin; Yang, Yi; Wang, Bo; Fu, John Y.; Yin, Shizhuo; Guo, Ruyan; Yu, Francis T.

2004-10-01

Optical windows have been widely used in optical spectrographic processing system. In this paper, various window profiles, such as rectangular, triangular, Hamming, Hanning, and Blackman etc., have been investigated in detail, regarding their effect on the generated spectrograms, such as joint time-frequency resolution ΔtΔw, the sidelobe amplitude attenuation etc.. All of these windows can be synthesized in a photorefractive crystal by angular multiplexing holographic technique, which renders the system more adaptive. Experimental results are provided.

Discrimination of side-window glass of Korean autos by laser ablation inductively coupled plasma mass spectrometry.

PubMed

Lee, Sin-Woo; Ryu, Jong-Sik; Min, Ji-Sook; Choi, Man-Yong; Lee, Kwang-Sik; Shin, Woo-Jin

2016-07-15

Fragments of glass from cars are often found at crime scenes and can be crucial evidence for solving the crime. The glass fragments are important as trace evidence at crime scenes related to car accidents and burgled homes. By identifying the origin of glass fragments, it is possible to infer the identity of a suspect. Our results represent a promising approach to a thorough forensic investigation of car glass. Thirty-five samples from the side windows of cars produced and used in South Korea were collected from the official agencies of five car manufacturers and from two glassmakers. In addition, 120 samples from side mirrors were collected from the same suppliers as well as from small businesses. Their chemical compositions (including Pb isotopes) were analyzed using laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) and linear discriminant analysis (LDA) was performed. The percentages of major elements (Si, Ca, and Fe) in side-window glass varied within narrow ranges (30.0 ± 2.36%, 5.93 ± 0.52%, and 0.33 ± 0.05%, respectively), while the differences among Pb isotope ratios were not significant. In contrast, light rare earth elements (LREEs) were different from each glassmaker. From the LDA, the types of side-window glass were successfully discriminated according to car manufacturer, glassmaker, and even glass thickness. However, glass from side mirrors cannot be used for good forensic identifiers. Discrimination techniques for side-window glass, although not for side mirrors, using chemical compositions combined with multivariate statistical analyses provide evidence for forensic investigations. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

Window type: 2x3 fixed multipaned steel window flanked by 1x3 ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Window type: 2x3 fixed multipaned steel window flanked by 1x3 multipaned steel casements. Concrete sill and spandrel also illustrated. Building 43, facing east - Harbor Hills Housing Project, 26607 Western Avenue, Lomita, Los Angeles County, CA

Switchable Materials for Smart Windows.

PubMed

Wang, Yang; Runnerstrom, Evan L; Milliron, Delia J

2016-06-07

This article reviews the basic principles of and recent developments in electrochromic, photochromic, and thermochromic materials for applications in smart windows. Compared with current static windows, smart windows can dynamically modulate the transmittance of solar irradiation based on weather conditions and personal preferences, thus simultaneously improving building energy efficiency and indoor human comfort. Although some smart windows are commercially available, their widespread implementation has not yet been realized. Recent advances in nanostructured materials provide new opportunities for next-generation smart window technology owing to their unique structure-property relations. Nanomaterials can provide enhanced coloration efficiency, faster switching kinetics, and longer lifetime. In addition, their compatibility with solution processing enables low-cost and high-throughput fabrication. This review also discusses the importance of dual-band modulation of visible and near-infrared (NIR) light, as nearly 50% of solar energy lies in the NIR region. Some latest results show that solution-processable nanostructured systems can selectively modulate the NIR light without affecting the visible transmittance, thus reducing energy consumption by air conditioning, heating, and artificial lighting.

Window Frame Types | Efficient Windows Collaborative

Science.gov Websites

metal frames. Metal Frames Metal Frame with Thermal Break Non-metal Frames Non-metal There is a variety of non-metal framing materials for windows including, wood, wood with metal/vinyl cladding, vinyl disadvantages. Non-metal Frames Non-metal Frame, Thermally Improved Does frame material type matter? The

Developmental Origins of Chronic Kidney Disease: Should We Focus on Early Life?

PubMed Central

Tain, You-Lin; Hsu, Chien-Ning

2017-01-01

Chronic kidney disease (CKD) is becoming a global burden, despite recent advances in management. CKD can begin in early life by so-called “developmental programming” or “developmental origins of health and disease” (DOHaD). Early-life insults cause structural and functional changes in the developing kidney, which is called renal programming. Epidemiological and experimental evidence supports the proposition that early-life adverse events lead to renal programming and make subjects vulnerable to developing CKD and its comorbidities in later life. In addition to low nephron endowment, several mechanisms have been proposed for renal programming. The DOHaD concept opens a new window to offset the programming process in early life to prevent the development of adult kidney disease, namely reprogramming. Here, we review the key themes on the developmental origins of CKD. We have particularly focused on the following areas: evidence from human studies support fetal programming of kidney disease; insight from animal models of renal programming; hypothetical mechanisms of renal programming; alterations of renal transcriptome in response to early-life insults; and the application of reprogramming interventions to prevent the programming of kidney disease. PMID:28208659

Beyond the dyad: making Developmental Origins of Health and Disease (DOHaD) interventions more inclusive.

PubMed

Pentecost, M; Ross, F C; Macnab, A

2018-02-01

Pregnant women, children under 2 and the first thousand days of life have been principal targets for Developmental Origins of Health and Disease interventions. This paradigm has been criticized for laying responsibility for health outcomes on pregnant women and mothers and through the thousand days focus inadvertently deflecting attention from other windows for intervention. Drawing on insights from the South African context, this commentary argues for integrated and inclusive interventions that encompass broader social framings. First, future interventions should include a wider range of actors. Second, broader action frameworks should encompass life-course approaches that identify multiple windows of opportunity for intervention. Using two examples - the inclusion of men, and engagement with adolescents - this commentary offers strategies for producing more inclusive interventions by using a broader social framework.

30 CFR 18.30 - Windows and lenses.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Windows and lenses. 18.30 Section 18.30 Mineral... § 18.30 Windows and lenses. (a) MSHA may waive testing of materials for windows or lenses except headlight lenses. When tested, material for windows or lenses shall meet the test requirements prescribed in...

Measured Rattle Threshold of Residential House Windows

NASA Technical Reports Server (NTRS)

Sizov, Natalia; Schultz, Troy; Hobbs, Christopher; Klos, Jacob

2008-01-01

Window rattle is a common indoor noise effect in houses exposed to low frequency noise from such sources as railroads, blast noise and sonic boom. Human perception of rattle can be negative that is a motivating factor of the current research effort to study sonic boom induced window rattle. A rattle study has been conducted on residential houses containing windows of different construction at a variety of geographic locations within the United States. Windows in these houses were excited by a portable, high-powered loudspeaker and enclosure specifically designed to be mounted on the house exterior to cover an entire window. Window vibration was measured with accelerometers placed on different window components. Reference microphones were also placed inside the house and inside of the loudspeaker box. Swept sine excitation was used to identify the vibration threshold at which the response of the structure becomes non-linear and begins to rattle. Initial results from this study are presented and discussed. Future efforts will continue to explore the rattle occurrence in windows of residential houses exposed to sonic booms.

Heat shock protein expression as guidance for the therapeutic window of retinal laser therapy

NASA Astrophysics Data System (ADS)

Wang, Jenny; Huie, Philip; Dalal, Roopa; Lee, Seungjun; Tan, Gavin; Lee, Daeyoung; Lavinksy, Daniel; Palanker, Daniel

2016-03-01

Unlike conventional photocoagulation, non-damaging retinal laser therapy (NRT) limits laser-induced heating to stay below the retinal damage threshold and therefore requires careful dosimetry. Without the adverse effects associated with photocoagulation, NRT can be applied to critical areas of the retina and repeatedly to manage chronic disorders. Although the clinical benefits of NRT have been demonstrated, the mechanism of therapeutic effect and width of the therapeutic window below damage threshold are not well understood. Here, we measure activation of heat shock response via laser-induced hyperthermia as one indication of cellular response. A 577 nm laser is used with the Endpoint Management (EpM) user interface, a titration algorithm, to set experimental pulse energies relative to a barely visible titration lesion. Live/dead staining and histology show that the retinal damage threshold in rabbits is at 40% of titration energy on EpM scale. Heat shock protein 70 (HSP70) expression in the retinal pigment epithelium (RPE) was detected by whole-mount immunohistochemistry after different levels of laser treatment. We show HSP70 expression in the RPE beginning at 25% of titration energy indicating that there is a window for NRT between 25% and 40% with activation of the heat shock protein expression in response to hyperthermia. HSP70 expression is also seen at the perimeter of damaging lesions, as expected based on a computational model of laser heating. Expression area for each pulse energy setting varied between laser spots due to pigmentation changes, indicating the relatively narrow window of non-damaging activation and highlighting the importance of proper titration.

Evaluation of Energy Efficiency Performance of Heated Windows

NASA Astrophysics Data System (ADS)

Jammulamadaka, Hari Swarup

The study about the evaluation of the performance of the heated windows was funded by the WVU Research Office as a technical assistance award at the 2014 TransTech Energy Business Development Conference to the Green Heated Glass company/project owned by Frank Dlubak. The award supports a WVU researcher to conduct a project important for commercialization. This project was awarded to the WVU Industrial Assessment Center in 2015. The current study attempted to evaluate the performance of the heated windows by developing an experimental setup to test the window at various temperatures by varying the current input to the window. The heated double pane window was installed in an insulated box. A temperature gradient was developed across the window by cooling one side of the window using gel based ice packs. The other face of the window was heated by passing current at different wattages through the window. The temperature of the inside and outside panes, current and voltage input, room and box temperature were recorded, and used to calculate the apparent R-value of the window when not being heated vs when being heated. It has been concluded from the study that the heated double pane window is more effective in reducing heat losses by as much as 50% than a non-heated double pane window, if the window temperature is maintained close to the room temperature. If the temperature of the window is much higher than the room temperature, the losses through the window appear to increase beyond that of a non-heated counterpart. The issues encountered during the current round of experiments are noted, and recommendations provided for future studies.

Active noise attenuation in ventilation windows.

PubMed

Huang, Huahua; Qiu, Xiaojun; Kang, Jian

2011-07-01

The feasibility of applying active noise control techniques to attenuate low frequency noise transmission through a natural ventilation window into a room is investigated analytically and experimentally. The window system is constructed by staggering the opening sashes of a spaced double glazing window to allow ventilation and natural light. An analytical model based on the modal expansion method is developed to calculate the low frequency sound field inside the window and the room and to be used in the active noise control simulations. The effectiveness of the proposed analytical model is validated by using the finite element method. The performance of the active control system for a window with different source and receiver configurations are compared, and it is found that the numerical and experimental results are in good agreement and the best result is achieved when the secondary sources are placed in the center at the bottom of the staggered window. The extra attenuation at the observation points in the optimized window system is almost equivalent to the noise reduction at the error sensor and the frequency range of effective control is up to 390 Hz in the case of a single channel active noise control system. © 2011 Acoustical Society of America

Window type: 4x4 multipaned steel window flanked by 1x4 multipaned ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Window type: 4x4 multipaned steel window flanked by 1x4 multipaned steel, casements. Concrete stoop, entry overhang and pipe rail detail also illustrated. Building 36, facing northwest - Harbor Hills Housing Project, 26607 Western Avenue, Lomita, Los Angeles County, CA

Lagrangian technique to calculate window interface velocity from shock velocity measurements: Application for quartz windows

DOE PAGES

McCoy, Chad A.; Knudson, Marcus D.

2017-08-24

Measurement of the window interface velocity is a common technique for investigating the dynamic response materials at high strain rates. However, these measurements are limited in pressure to the range where the window remains transparent. The most common window material for this application is lithium fluoride, which under single shock compression becomes opaque at ~200 GPa. To date, no other window material has been identified for use at higher pressures. Here, we present a Lagrangian technique to calculate the interface velocity from a continuously measured shock velocity, with application to quartz. The quartz shock front becomes reflective upon melt, atmore » ~100 GPa, enabling the use of velocity interferometry to continuously measure the shock velocity. This technique overlaps with the range of pressures accessible with LiF windows and extends the region where wave profile measurements are possible to pressures in excess of 2000 GPa. Lastly, we show through simulated data that the technique accurately reproduces the interface velocity within 20% of the initial state, and that the Lagrangian technique represents a significant improvement over a simple linear approximation.« less

Lagrangian technique to calculate window interface velocity from shock velocity measurements: Application for quartz windows

DOE Office of Scientific and Technical Information (OSTI.GOV)

McCoy, Chad A.; Knudson, Marcus D.

Measurement of the window interface velocity is a common technique for investigating the dynamic response materials at high strain rates. However, these measurements are limited in pressure to the range where the window remains transparent. The most common window material for this application is lithium fluoride, which under single shock compression becomes opaque at ~200 GPa. To date, no other window material has been identified for use at higher pressures. Here, we present a Lagrangian technique to calculate the interface velocity from a continuously measured shock velocity, with application to quartz. The quartz shock front becomes reflective upon melt, atmore » ~100 GPa, enabling the use of velocity interferometry to continuously measure the shock velocity. This technique overlaps with the range of pressures accessible with LiF windows and extends the region where wave profile measurements are possible to pressures in excess of 2000 GPa. Lastly, we show through simulated data that the technique accurately reproduces the interface velocity within 20% of the initial state, and that the Lagrangian technique represents a significant improvement over a simple linear approximation.« less

Current status of photoprotection by window glass, automobile glass, window films, and sunglasses.

PubMed

Almutawa, Fahad; Vandal, Robert; Wang, Steven Q; Lim, Henry W

2013-04-01

Ultraviolet radiation (UVR) has known adverse effects on the skin and eyes. Practitioners are becoming more aware of the importance of outdoor photoprotection. However, little attention is directed to the exposure of the skin and eyes to UVR through the window glass or sunglasses. The amount of ultraviolet transmission through glass depends mainly on the type of the glass. All types of commercial and automobile glass block the majority of ultraviolet-B; however, the degree of ultraviolet-A transmission depends on the type of glass. Laminated glass offers better UVA protection than tempered glass; new safety regulations for automobiles may result in increased use of laminated glass for side windows. Window films can be applied to glass to increase UVR protection. Sunglasses need to be compliant with one of the national standards; a wraparound style or side shields offer the best protection. Increased understanding by practitioners on the transmission of UVR through glass, window films, and sunglasses would allow them to better educate the public and to better manage photosensitive patients. © 2013 John Wiley & Sons A/S.

Polarization leakage in epoch of reionization windows - III. Wide-field effects of narrow-field arrays

NASA Astrophysics Data System (ADS)

Asad, K. M. B.; Koopmans, L. V. E.; Jelić, V.; de Bruyn, A. G.; Pandey, V. N.; Gehlot, B. K.

2018-05-01

Leakage of polarized Galactic diffuse emission into total intensity can potentially mimic the 21-cm signal coming from the epoch of reionization (EoR), as both of them might have fluctuating spectral structure. Although we are sensitive to the EoR signal only in small fields of view, chromatic side-lobes from further away can contaminate the inner region. Here, we explore the effects of leakage into the `EoR window' of the cylindrically averaged power spectra (PS) within wide fields of view using both observation and simulation of the 3C196 and North Celestial Pole (NCP) fields, two observing fields of the LOFAR-EoR project. We present the polarization PS of two one-night observations of the two fields and find that the NCP field has higher fluctuations along frequency, and consequently exhibits more power at high-k∥ that could potentially leak to Stokes I. Subsequently, we simulate LOFAR observations of Galactic diffuse polarized emission based on a model to assess what fraction of polarized power leaks into Stokes I because of the primary beam. We find that the rms fractional leakage over the instrumental k-space is 0.35 {per cent} in the 3C196 field and 0.27 {per cent} in the NCP field, and it does not change significantly within the diameters of 15°, 9°, and 4°. Based on the observed PS and simulated fractional leakage, we show that a similar level of leakage into Stokes I is expected in the 3C196 and NCP fields, and the leakage can be considered to be a bias in the PS.

Window type: paired 3x2 multipaned steel window flanked by 1x3 ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Window type: paired 3x2 multipaned steel window flanked by 1x3 multipaned steel casements, breaking building corner. Broad overhanging eave also illustrated. Second story detail. Building 13, facing east - Harbor Hills Housing Project, 26607 Western Avenue, Lomita, Los Angeles County, CA

An Introduction to X Window Application Development

DTIC Science & Technology

1992-03-23

Acquisition and Policy Evaluation program using Cognitive Feed- back ( ESKAPE /CF) from the SunView windowing system to X Window. The new application...the generic X Window System. This thesis converts an Expert System Knowledge Acquisition and Policy Evaluation program using Cognitive Feedback ( ESKAPE ...15 IV. XESKAPE/CF: THE X WINDOW VERSION OF ESKAPE /CF ........................ 16 A. FUNCTIONAL COMPARISON TO

Window Insulation: How to Sort Through the Options.

ERIC Educational Resources Information Center

Miller, Barbara

This two-part report explores the efforts of businesses and individuals to improve the thermal performance of windows. Part I discusses the basics of what makes a window product insulate or save energy. Topic areas addressed include saving energy lost through windows, key components of window insulation, three basic types of window insulation,…

Orion Hatch Window Testing

NASA Image and Video Library

2018-04-09

Inside a laboratory in the Neil Armstrong Operations and Checkout Building at NASA's Kennedy Space Center in Florida, Mark Nurge, Ph.D., at left, a physicist in the Applied Physics Lab with the center's Exploration Research and Technology Programs, and Bence Bartha, Ph.D., a specialist in non-destructive testing with URS Federal Services, are performing the first optical quality testing on a full window stack that is ready for installation in the docking hatch of NASA's Orion spacecraft. The data from the tests will help improve the requirements for manufacturing tolerances on Orion's windows and verify how the window should perform in space. Orion is being prepared for its first integrated uncrewed flight atop NASA's Space Launch System rocket on Exploration Mission-1.

Window type: paired 2x4 multipaned steel windows flanked by 1x4 ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Window type: paired 2x4 multipaned steel windows flanked by 1x4 multipaned steel casements, breaking building corner. Raised panel door front entry also illustrated. Ground floor detail Building 19, facing north - Harbor Hills Housing Project, 26607 Western Avenue, Lomita, Los Angeles County, CA

Worldwide variability in growth and its association with health: Incorporating body composition, developmental plasticity, and intergenerational effects.

PubMed

Wells, Jonathan C K

2017-03-01

In their seminal book "Worldwide variation in human growth," published in 1976, Eveleth and Tanner highlighted substantial variability within and between populations in the magnitude and schedule of human growth. In the four decades since then, research has clarified why growth variability is so closely associated with human health. First, growth patterns are strongly associated with body composition, both in the short- and long-term. Poor growth in early life constrains the acquisition of lean tissue, while compensatory "catch-up" growth may elevate body fatness. Second, these data are examples of the fundamental link between growth and developmental plasticity. Growth is highly sensitive to ecological stresses and stimuli during early "critical windows," but loses much of this sensitivity as it undergoes canalization during early childhood. Crucially, the primary source of stimuli during early "critical windows" is not the external environment itself, but rather maternal phenotype, which transduces the impact of ecological conditions. Maternal phenotype, representing many dimensions of "capital," thus generates a powerful impact on the developmental trajectory of the offspring. There is increasing evidence that low levels of maternal capital impact the offspring's size at birth, schedule of maturation, and body composition and physiological function in adulthood. While evidence has accrued of substantial heritability in adult height, it is clear that the pathway through which it is attained has major implications for metabolic phenotype. Integrating these perspectives is important for understanding how developmental plasticity may on the one hand contribute to adaptation, while on the other shape susceptibility to non-communicable disease. © 2017 Wiley Periodicals, Inc.

Purged window apparatus utilizing heated purge gas

DOEpatents

Ballard, Evan O.

1984-01-01

A purged window apparatus utilizing tangentially injected heated purge gases in the vicinity of electromagnetic radiation transmitting windows, and a tapered external mounting tube to accelerate these gases to provide a vortex flow on the window surface and a turbulent flow throughout the mounting tube. Use of this apparatus prevents backstreaming of gases under investigation which are flowing past the mouth of the mounting tube which would otherwise deposit on the windows. Lengthy spectroscopic investigations and analyses can thereby be performed without the necessity of interrupting the procedures in order to clean or replace contaminated windows.

Dynamic CRM occupancy reflects a temporal map of developmental progression.

PubMed

Wilczyński, Bartek; Furlong, Eileen E M

2010-06-22

Development is driven by tightly coordinated spatio-temporal patterns of gene expression, which are initiated through the action of transcription factors (TFs) binding to cis-regulatory modules (CRMs). Although many studies have investigated how spatial patterns arise, precise temporal control of gene expression is less well understood. Here, we show that dynamic changes in the timing of CRM occupancy is a prevalent feature common to all TFs examined in a developmental ChIP time course to date. CRMs exhibit complex binding patterns that cannot be explained by the sequence motifs or expression of the TFs themselves. The temporal changes in TF binding are highly correlated with dynamic patterns of target gene expression, which in turn reflect transitions in cellular function during different stages of development. Thus, it is not only the timing of a TF's expression, but also its temporal occupancy in refined time windows, which determines temporal gene expression. Systematic measurement of dynamic CRM occupancy may therefore serve as a powerful method to decode dynamic changes in gene expression driving developmental progression.

Window Area and Development Drive Spatial Variation in Bird-Window Collisions in an Urban Landscape

PubMed Central

Hager, Stephen B.; Cosentino, Bradley J.; McKay, Kelly J.; Monson, Cathleen; Zuurdeeg, Walt; Blevins, Brian

2013-01-01

Collisions with windows are an important human-related threat to birds in urban landscapes. However, the proximate drivers of collisions are not well understood, and no study has examined spatial variation in mortality in an urban setting. We hypothesized that the number of fatalities at buildings varies with window area and habitat features that influence avian community structure. In 2010 we documented bird-window collisions (BWCs) and characterized avian community structure at 20 buildings in an urban landscape in northwestern Illinois, USA. For each building and season, we conducted 21 daily surveys for carcasses and nine point count surveys to estimate relative abundance, richness, and diversity. Our sampling design was informed by experimentally estimated carcass persistence times and detection probabilities. We used linear and generalized linear mixed models to evaluate how habitat features influenced community structure and how mortality was affected by window area and factors that correlated with community structure. The most-supported model was consistent for all community indices and included effects of season, development, and distance to vegetated lots. BWCs were related positively to window area and negatively to development. We documented mortalities for 16/72 (22%) species (34 total carcasses) recorded at buildings, and BWCs were greater for juveniles than adults. Based on the most-supported model of BWCs, the median number of annual predicted fatalities at study buildings was 3 (range = 0–52). These results suggest that patchily distributed environmental resources and levels of window area in buildings create spatial variation in BWCs within and among urban areas. Current mortality estimates place little emphasis on spatial variation, which precludes a fundamental understanding of the issue. To focus conservation efforts, we illustrate how knowledge of the structural and environmental factors that influence bird-window collisions can be used

Window area and development drive spatial variation in bird-window collisions in an urban landscape.

PubMed

Hager, Stephen B; Cosentino, Bradley J; McKay, Kelly J; Monson, Cathleen; Zuurdeeg, Walt; Blevins, Brian

2013-01-01

Collisions with windows are an important human-related threat to birds in urban landscapes. However, the proximate drivers of collisions are not well understood, and no study has examined spatial variation in mortality in an urban setting. We hypothesized that the number of fatalities at buildings varies with window area and habitat features that influence avian community structure. In 2010 we documented bird-window collisions (BWCs) and characterized avian community structure at 20 buildings in an urban landscape in northwestern Illinois, USA. For each building and season, we conducted 21 daily surveys for carcasses and nine point count surveys to estimate relative abundance, richness, and diversity. Our sampling design was informed by experimentally estimated carcass persistence times and detection probabilities. We used linear and generalized linear mixed models to evaluate how habitat features influenced community structure and how mortality was affected by window area and factors that correlated with community structure. The most-supported model was consistent for all community indices and included effects of season, development, and distance to vegetated lots. BWCs were related positively to window area and negatively to development. We documented mortalities for 16/72 (22%) species (34 total carcasses) recorded at buildings, and BWCs were greater for juveniles than adults. Based on the most-supported model of BWCs, the median number of annual predicted fatalities at study buildings was 3 (range = 0-52). These results suggest that patchily distributed environmental resources and levels of window area in buildings create spatial variation in BWCs within and among urban areas. Current mortality estimates place little emphasis on spatial variation, which precludes a fundamental understanding of the issue. To focus conservation efforts, we illustrate how knowledge of the structural and environmental factors that influence bird-window collisions can be used to

Water bubble in front of JEM window

NASA Image and Video Library

2015-03-20

View of water bubble formed in front of the Japanese Experiment Module (JEM) window. The JEM Exposed Facility (JEF) is visible in the background through the window and reflected in the water. Scratches visible on the window.

Computed Tomography Window Blending: Feasibility in Thoracic Trauma.

PubMed

Mandell, Jacob C; Wortman, Jeremy R; Rocha, Tatiana C; Folio, Les R; Andriole, Katherine P; Khurana, Bharti

2018-02-07

This study aims to demonstrate the feasibility of processing computed tomography (CT) images with a custom window blending algorithm that combines soft-tissue, bone, and lung window settings into a single image; to compare the time for interpretation of chest CT for thoracic trauma with window blending and conventional window settings; and to assess diagnostic performance of both techniques. Adobe Photoshop was scripted to process axial DICOM images from retrospective contrast-enhanced chest CTs performed for trauma with a window-blending algorithm. Two emergency radiologists independently interpreted the axial images from 103 chest CTs with both blended and conventional windows. Interpretation time and diagnostic performance were compared with Wilcoxon signed-rank test and McNemar test, respectively. Agreement with Nexus CT Chest injury severity was assessed with the weighted kappa statistic. A total of 13,295 images were processed without error. Interpretation was faster with window blending, resulting in a 20.3% time saving (P < .001), with no difference in diagnostic performance, within the power of the study to detect a difference in sensitivity of 5% as determined by post hoc power analysis. The sensitivity of the window-blended cases was 82.7%, compared to 81.6% for conventional windows. The specificity of the window-blended cases was 93.1%, compared to 90.5% for conventional windows. All injuries of major clinical significance (per Nexus CT Chest criteria) were correctly identified in all reading sessions, and all negative cases were correctly classified. All readers demonstrated near-perfect agreement with injury severity classification with both window settings. In this pilot study utilizing retrospective data, window blending allows faster preliminary interpretation of axial chest CT performed for trauma, with no significant difference in diagnostic performance compared to conventional window settings. Future studies would be required to assess the

Low-Emissivity, Energy-Control, Retrofit Window Film: Final Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Winckler, Lisa

Solutia Performance Films, utilizing funding from the U.S. Department of Energy's Buildings Technologies Program, completed research to develop, validate, and commercialize a range of cost-effective, low-emissivity energy-control retrofit window films with significantly improved emissivity over current technology. These films, sold under the EnerLogic® trade name, offer the energy-saving properties of modern low-e windows, with several advantages over replacement windows, such as: lower initial installation cost, a significantly lower product carbon footprint, and an ability to provide a much faster return on investment. EnerLogic® window films also offer significantly greater energy savings than previously available with window films with similar visiblemore » light transmissions. EnerLogic® window films offer these energy-saving advantages over other window films due to its ability to offer both summer cooling and winter heating savings. Unlike most window films, that produce savings only during the cooling season, EnerLogic® window film is an all-season, low-emissivity (low-e) film that produces both cooling and heating season savings. This paper will present technical information on the development hurdles as well as details regarding the following claims being made about EnerLogic® window film, which can be found at www.EnerLogicfilm.com: 1. Other window film technologies save energy. EnerLogic® window film's patent-pending coating delivers excellent energy efficiency in every season, so no other film can match its annual dollar or energy consumption savings. 2. EnerLogic® window film is a low-cost, high-return technology that compares favorably to other popular energy-saving measures both in terms of energy efficiency and cost savings. In fact, EnerLogic® window film typically outperforms most of the alternatives in terms of simple payback. 3. EnerLogic® window film provides unparalleled glass insulating capabilities for window film products. With

Carbon Nanotube Reinforced Flexible Windows for Blast Protection

DTIC Science & Technology

2010-07-01

transparent plastic composite for use as a material for window or as a laminate layer in the blast-resistant glazed window. This program focused...materials for window or as a laminate layer in the blast-resistant glazed window. It is obvious that further increasing the mechanical properties of...Dr. Ben Wang led the effort for design/fabrication of windows from the nanotube assembly and lamination experiments. 6 3. RESULTS AND

Developmental evidence for obstetric adaptation of the human female pelvis.

PubMed

Huseynov, Alik; Zollikofer, Christoph P E; Coudyzer, Walter; Gascho, Dominic; Kellenberger, Christian; Hinzpeter, Ricarda; Ponce de León, Marcia S

2016-05-10

The bony pelvis of adult humans exhibits marked sexual dimorphism, which is traditionally interpreted in the framework of the "obstetrical dilemma" hypothesis: Giving birth to large-brained/large-bodied babies requires a wide pelvis, whereas efficient bipedal locomotion requires a narrow pelvis. This hypothesis has been challenged recently on biomechanical, metabolic, and biocultural grounds, so that it remains unclear which factors are responsible for sex-specific differences in adult pelvic morphology. Here we address this issue from a developmental perspective. We use methods of biomedical imaging and geometric morphometrics to analyze changes in pelvic morphology from late fetal stages to adulthood in a known-age/known-sex forensic/clinical sample. Results show that, until puberty, female and male pelves exhibit only moderate sexual dimorphism and follow largely similar developmental trajectories. With the onset of puberty, however, the female trajectory diverges substantially from the common course, resulting in rapid expansion of obstetrically relevant pelvic dimensions up to the age of 25-30 y. From 40 y onward females resume a mode of pelvic development similar to males, resulting in significant reduction of obstetric dimensions. This complex developmental trajectory is likely linked to the pubertal rise and premenopausal fall of estradiol levels and results in the obstetrically most adequate pelvic morphology during the time of maximum female fertility. The evidence that hormones mediate female pelvic development and morphology supports the view that solutions of the obstetrical dilemma depend not only on selection and adaptation but also on developmental plasticity as a response to ecological/nutritional factors during a female's lifetime.

Developmental evidence for obstetric adaptation of the human female pelvis

PubMed Central

Huseynov, Alik; Zollikofer, Christoph P. E.; Coudyzer, Walter; Gascho, Dominic; Kellenberger, Christian; Hinzpeter, Ricarda; Ponce de León, Marcia S.

2016-01-01

The bony pelvis of adult humans exhibits marked sexual dimorphism, which is traditionally interpreted in the framework of the “obstetrical dilemma” hypothesis: Giving birth to large-brained/large-bodied babies requires a wide pelvis, whereas efficient bipedal locomotion requires a narrow pelvis. This hypothesis has been challenged recently on biomechanical, metabolic, and biocultural grounds, so that it remains unclear which factors are responsible for sex-specific differences in adult pelvic morphology. Here we address this issue from a developmental perspective. We use methods of biomedical imaging and geometric morphometrics to analyze changes in pelvic morphology from late fetal stages to adulthood in a known-age/known-sex forensic/clinical sample. Results show that, until puberty, female and male pelves exhibit only moderate sexual dimorphism and follow largely similar developmental trajectories. With the onset of puberty, however, the female trajectory diverges substantially from the common course, resulting in rapid expansion of obstetrically relevant pelvic dimensions up to the age of 25–30 y. From 40 y onward females resume a mode of pelvic development similar to males, resulting in significant reduction of obstetric dimensions. This complex developmental trajectory is likely linked to the pubertal rise and premenopausal fall of estradiol levels and results in the obstetrically most adequate pelvic morphology during the time of maximum female fertility. The evidence that hormones mediate female pelvic development and morphology supports the view that solutions of the obstetrical dilemma depend not only on selection and adaptation but also on developmental plasticity as a response to ecological/nutritional factors during a female’s lifetime. PMID:27114515

Narrow-headed garter snake (Thamnophis rufipunctatus)

USGS Publications Warehouse

Nowak, Erika M.

2006-01-01

The narrow-headed garter snake is a harmless, nonvenomous snake that is distinguished by its elongated, triangular-shaped head and the red or dark spots on its olive to tan body. Today, the narrow-headed garter snake is a species of special concern in the United States because of its decline over much of its historic range. Arizona's Oak Creek has historically contained the largest population of narrow-headed garter snakes in the United States. The U.S. Geological Survey (USGS) and the Arizona Game and Fish Department jointly funded research by USGS scientists in Oak Creek to shed light on the factors causing declining population numbers. The research resulted in better understanding of the snake's habitat needs, winter and summer range, and dietary habits. Based on the research findings, the U.S. Forest Service has developed recommendations that visitors and local residents can adopt to help slow the decline of the narrow-headed garter snake in Oak Creek.

Infrared sensor and window system issues

NASA Astrophysics Data System (ADS)

Hargraves, Charles H., Jr.; Martin, James M.

1992-12-01

EO/IR windows are a significant challenge for the weapon system sensor designer who must design for high EO performance, low radar cross section (RCS), supersonic flight, durability, producibility and affordable initial and life cycle costs. This is particularly true in the 8 to 12 micron IR band at which window materials and coating choices are limited by system design requirements. The requirements also drive the optimization of numerous mechanical, optical, materials, and electrical parameters. This paper addresses the EO/IR window as a system design challenge. The interrelationship of the optical, mechanical, and system design processes are examined. This paper presents a summary of the test results, trade studies and analyses that were performed for multi-segment, flight-worthy optical windows with superior optical performance at subsonic and supersonic aircraft velocities and reduced radar cross section. The impact of the window assembly on EO system modulation transfer function (MTF) and sensitivity will be discussed. The use of conductive coatings for shielding/signature control will be discussed.

Window contamination on Expose-R

NASA Astrophysics Data System (ADS)

Demets, R.; Bertrand, M.; Bolkhovitinov, A.; Bryson, K.; Colas, C.; Cottin, H.; Dettmann, J.; Ehrenfreund, P.; Elsaesser, A.; Jaramillo, E.; Lebert, M.; van Papendrecht, G.; Pereira, C.; Rohr, T.; Saiagh, K.

2015-01-01

Expose is a multi-user instrument for astrobiological and astrochemical experiments in space. Installed at the outer surface of the International Space Station, it enables investigators to study the impact of the open space environment on biological and biochemical test samples. Two Expose missions have been completed so far, designated as Expose-E (Rabbow et al. 2012) and Expose-R (Rabbow et al. this issue). One of the space-unique environmental factors offered by Expose is full-spectrum, ultraviolet (UV)-rich electromagnetic radiation from the Sun. This paper describes and analyses how on Expose-R, access of the test samples to Solar radiation degraded during space exposure in an unpredicted way. Several windows in front of the Sun-exposed test samples acquired a brown shade, resulting in a reduced transparency in visible light, UV and vacuum UV (VUV). Post-flight investigations revealed the discolouration to be caused by a homogenous film of cross-linked organic polymers at the inside of the windows. The chemical signature varied per sample carrier. No such films were found on windows from sealed, pressurized compartments, or on windows that had been kept out of the Sun. This suggests that volatile compounds originating from the interior of the Expose facility were cross-linked and photo-fixed by Solar irradiation at the rear side of the windows. The origin of the volatiles was not fully identified; most probably there was a variety of sources involved including the biological test samples, adhesives, plastics and printed circuit boards. The outer surface of the windows (pointing into space) was chemically impacted as well, with a probable effect on the transparency in VUV. The reported analysis of the window contamination on Expose-R is expected to help the interpretation of the scientific results and offers possibilities to mitigate this problem on future missions - in particular Expose-R2, the direct successor of Expose-R.

Interior and Exterior Low-E Storm Window Installation

ScienceCinema

Witters, Sarah

2018-01-16

Until recently, energy-efficient window retrofit options have largely been limited to repair or replacement; leaving the homeowner to decide between affordability and deeper energy savings. A new and improved low-e storm window boasts a combination of curb appeal and energy efficiency, all for a fraction of the cost of window replacement. A recent whole-home experiment performed by PNNL suggests that attaching low-e storm windows can result in as much energy savings replacing the windows.

Window Cleaner—New and Improved?

NASA Astrophysics Data System (ADS)

Jacobsen, Erica K.

2007-11-01

A recent coupon advertisement for window cleaner in the Sunday newspaper was reminiscent of a past JCE Classroom Activity . The new product says it offers a cheaper way to clean your windows and is a way to cut down on the number of plastic spray containers you throw away.

USB Storage Device Forensics for Windows 10.

PubMed

Arshad, Ayesha; Iqbal, Waseem; Abbas, Haider

2018-05-01

Significantly increased use of USB devices due to their user-friendliness and large storage capacities poses various threats for many users/companies in terms of data theft that becomes easier due to their efficient mobility. Investigations for such data theft activities would require gathering critical digital information capable of recovering digital forensics artifacts like date, time, and device information. This research gathers three sets of registry and logs data: first, before insertion; second, during insertion; and the third, after removal of a USB device. These sets are analyzed to gather evidentiary information from Registry and Windows Event log that helps in tracking a USB device. This research furthers the prior research on earlier versions of Microsoft Windows and compares it with latest Windows 10 system. Comparison of Windows 8 and Windows 10 does not show much difference except for new subkey under USB Key in registry. However, comparison of Windows 7 with latest version indicates significant variances. © 2017 American Academy of Forensic Sciences.

46 CFR 127.440 - Operability of window coverings.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Operability of window coverings. 127.440 Section 127.440... ARRANGEMENTS Construction of Windows, Visibility, and Operability of Coverings § 127.440 Operability of window coverings. Any covering or protection placed over a window or porthole that could be used as a means of...

High-Temperature Optical Window Design

NASA Technical Reports Server (NTRS)

Roeloffs, Norman; Taranto, Nick

1995-01-01

A high-temperature optical window is essential to the optical diagnostics of high-temperature combustion rigs. Laser Doppler velocimetry, schlieren photography, light sheet visualization, and laser-induced fluorescence spectroscopy are a few of the tests that require optically clear access to the combustor flow stream. A design was developed for a high-temperature window that could withstand the severe environment of the NASA Lewis 3200 F Lean Premixed Prevaporized (LPP) Flame Tube Test Rig. The development of this design was both time consuming and costly. This report documents the design process and the lessons learned, in an effort to reduce the cost of developing future designs for high-temperature optical windows.

14 CFR 27.775 - Windshields and windows.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Windshields and windows. 27.775 Section 27.775 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT... § 27.775 Windshields and windows. Windshields and windows must be made of material that will not break...

14 CFR 29.775 - Windshields and windows.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Windshields and windows. 29.775 Section 29.775 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT... Accommodations § 29.775 Windshields and windows. Windshields and windows must be made of material that will not...

14 CFR 27.775 - Windshields and windows.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Windshields and windows. 27.775 Section 27.775 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT... § 27.775 Windshields and windows. Windshields and windows must be made of material that will not break...

14 CFR 27.775 - Windshields and windows.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Windshields and windows. 27.775 Section 27.775 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT... § 27.775 Windshields and windows. Windshields and windows must be made of material that will not break...

14 CFR 29.775 - Windshields and windows.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Windshields and windows. 29.775 Section 29.775 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT... Accommodations § 29.775 Windshields and windows. Windshields and windows must be made of material that will not...

14 CFR 29.775 - Windshields and windows.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Windshields and windows. 29.775 Section 29.775 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT... Accommodations § 29.775 Windshields and windows. Windshields and windows must be made of material that will not...

14 CFR 29.775 - Windshields and windows.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Windshields and windows. 29.775 Section 29.775 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT... Accommodations § 29.775 Windshields and windows. Windshields and windows must be made of material that will not...

14 CFR 27.775 - Windshields and windows.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Windshields and windows. 27.775 Section 27.775 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT... § 27.775 Windshields and windows. Windshields and windows must be made of material that will not break...

14 CFR 29.775 - Windshields and windows.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Windshields and windows. 29.775 Section 29.775 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT... Accommodations § 29.775 Windshields and windows. Windshields and windows must be made of material that will not...

14 CFR 27.775 - Windshields and windows.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Windshields and windows. 27.775 Section 27.775 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT... § 27.775 Windshields and windows. Windshields and windows must be made of material that will not break...

Weighted Parzen Windows for Pattern Classification

DTIC Science & Technology

1994-05-01

Nearest-Neighbor Rule The k-Nearest-Neighbor ( kNN ) technique is nonparametric, assuming nothing about the distribution of the data. Stated succinctly...probabilities P(wj I x) from samples." Raudys and Jain [20:255] advance this interpretation by pointing out that the kNN technique can be viewed as the...34Parzen window classifier with a hyper- rectangular window function." As with the Parzen-window technique, the kNN classifier is more accurate as the

Combined Pressure and Thermal Window System for Space Vehicles

NASA Technical Reports Server (NTRS)

Svartstrom, Kirk Nils (Inventor)

2015-01-01

A window system for a vehicle comprising a pressure and thermal window pane, a seal system, and a retainer system. The pressure and thermal window pane may be configured to provide desired pressure protection and desired thermal protection when exposed to an environment around the vehicle during operation of the vehicle. The pressure and thermal window pane may have a desired ductility. The seal system may be configured to contact the pressure and thermal window pane to seal the pressure and thermal window pane. The retainer system may be configured to hold the seal system and the pressure and thermal window pane.

Combined Pressure and Thermal Window System for Space Vehicles

NASA Technical Reports Server (NTRS)

Svartstrom, Kirk Nils (Inventor)

2017-01-01

A window system for a vehicle comprising a pressure and thermal window pane, a seal system, and a retainer system. The pressure and thermal window pane may be configured to provide desired pressure protection and desired thermal protection when exposed to an environment around the vehicle during operation of the vehicle. The pressure and thermal window pane may have a desired ductility. The seal system may be configured to contact the pressure and thermal window pane to seal the pressure and thermal window pane. The retainer system may be configured to hold the seal system and the pressure and thermal window pane.

Looking through the postdisaster policy window

NASA Astrophysics Data System (ADS)

Solecki, William D.; Michaels, Sarah

1994-07-01

Policy windows are transitory opportunities during which the likelihood of adopting new policy or legislative proposals is greater than usual. Accepted wisdom has held that natural disasters serve as focusing events that generate policy windows in their wake. This paper highlights the need for a more circumscribed understanding of when and where policy windows occur based on the experiences of three US regional planning organizations: a hand-picked commission of community leaders, a council of governments, and a special-purpose substate organization. The first operated in the San Francisco Bay Area of California following the Loma Prieta earthquake (October 1989), and the other two in South Carolina's Atlantic coastal plain after Hurricane Hugo (September 1989). The analysis concludes that natural disasters did not transform the agenda or mission of these entities. Policy windows were neither automatic outcomes of focusing events nor did they ensure the adoption of pertinent policy within the organizations investigated. Several conditions are minimally necessary for using policy windows to bring about hazard mitigation: comprehensive institutional conceptualization of hazards management, institutional strength and flexibility, and well-placed, effective policy entrepreneurs.

VIS-IR transmitting BGG glass windows

NASA Astrophysics Data System (ADS)

Bayya, Shyam S.; Chin, Geoff D.; Sanghera, Jasbinder S.; Aggarwal, Ishwar D.

2003-09-01

BaO-Ga2O3-GeO2 (BGG) glasses have the desired properties for various window applications in the 0.5-5 μm wavelength region. These glasses are low cost alternatives to the currently used window materials. Fabrication of a high optical quality 18" diameter BGG glass window has been demonstrated with a transmitted wave front error of λ/10 at 632 nm. BGG substrates have also been successfully tested for environmental weatherability (MIL-F-48616) and rain erosion durability up to 300 mph. Preliminary EMI grids have been successfully applied on BGG glasses demonstrating attenuation of 20dB in X and Ku bands. Although the mechanical properties of BGG glasses are acceptable for various window applications, it is demonstrated here that the properties can be further improved significantly by the glassceramization process. The ceramization process does not add any significant cost to the final window material. The crystallite size in the present glass-ceramic limits its transmission to the 2-5 μm region.

Manufacturing of diamond windows for synchrotron radiation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schildkamp, W.; Nikitina, L.

2012-09-15

A new diamond window construction is presented and explicit manufacturing details are given. This window will increase the power dissipation by about a factor of 4 over present day state of the art windows to absorb 600 W of power. This power will be generated by in-vacuum undulators with the storage ring ALBA operating at a design current of 400 mA. Extensive finite element (FE) calculations are included to predict the windows behavior accompanied by explanations for the chosen boundary conditions. A simple linear model was used to cross-check the FE calculations.

Window acoustic study for advanced turboprop aircraft

NASA Technical Reports Server (NTRS)

Prydz, R. A.; Balena, F. J.

1984-01-01

An acoustic analysis was performed to establish window designs for advanced turboprop powered aircraft. The window transmission loss requirements were based on A-weighted interior noise goals of 80 and 75 dBA. The analytical results showed that a triple pane window consisting of two glass outer panes and an inner pane of acrylic would provide the required transmission loss and meet the sidewall space limits. Two window test articles were fabricated for laboratory evaluation and verification of the predicted transmission loss. Procedures for performing laboratory tests are presented.

Multi-Window Controllers for Autonomous Space Systems

NASA Technical Reports Server (NTRS)

Lurie, B, J.; Hadaegh, F. Y.

1997-01-01

Multi-window controllers select between elementary linear controllers using nonlinear windows based on the amplitude and frequency content of the feedback error. The controllers are relatively simple to implement and perform much better than linear controllers. The commanders for such controllers only order the destination point and are freed from generating the command time-profiles. The robotic missions rely heavily on the tasks of acquisition and tracking. For autonomous and optimal control of the spacecraft, the control bandwidth must be larger while the feedback can (and, therefore, must) be reduced.. Combining linear compensators via multi-window nonlinear summer guarantees minimum phase character of the combined transfer function. It is shown that the solution may require using several parallel branches and windows. Several examples of multi-window nonlinear controller applications are presented.

Integration of ground-penetrating radar, ultrasonic tests and infrared thermography for the analysis of a precious medieval rose window

NASA Astrophysics Data System (ADS)

Nuzzo, L.; Calia, A.; Liberatore, D.; Masini, N.; Rizzo, E.

2010-04-01

The integration of high-resolution, non-invasive geophysical techniques (such as ground-penetrating radar or GPR) with emerging sensing techniques (acoustics, thermography) can complement limited destructive tests to provide a suitable methodology for a multi-scale assessment of the state of preservation, material and construction components of monuments. This paper presents the results of the application of GPR, infrared thermography (IRT) and ultrasonic tests to the 13th century rose window of Troia Cathedral (Apulia, Italy), affected by widespread decay and instability problems caused by the 1731 earthquake and reactivated by recent seismic activity. This integrated approach provided a wide amount of complementary information at different scales, ranging from the sub-centimetre size of the metallic joints between the various architectural elements, narrow fractures and thin mortar fillings, up to the sub-metre scale of the internal masonry structure of the circular ashlar curb linking the rose window to the façade, which was essential to understand the original building technique and to design an effective restoration strategy.

Cupola windows during Joint Operations

NASA Image and Video Library

2010-02-17

ISS022-E-066963 (17 Feb. 2010) --- This image is among the first taken through a first of its kind ?bay window? on the International Space Station, the seven-windowed Cupola. The image shows the coast of Algeria featuring (in the Cupola?s round window) an area between the cities of Dellys and Algiers. The image was recorded with a digital still camera using a 28mm lens setting. The Cupola, which a week and half ago was brought up to the orbital outpost by the STS-130 crew on the space shuttle Endeavour, will house controls for the station robotics and will be a location where crew members can operate the robotic arms and monitor other exterior activities.

Scale up of large ALON® and spinel windows

NASA Astrophysics Data System (ADS)

Goldman, Lee M.; Kashalikar, Uday; Ramisetty, Mohan; Jha, Santosh; Sastri, Suri

2017-05-01

Aluminum Oxynitride (ALON® Transparent Ceramic) and Magnesia Aluminate Spinel (Spinel) combine broadband transparency with excellent mechanical properties. Their cubic structure means that they are transparent in their polycrystalline form, allowing them to be manufactured by conventional powder processing techniques. Surmet has scaled up its ALON® production capability to produce and deliver windows as large as 4.4 sq ft. We have also produced our first 6 sq ft window. We are in the process of producing 7 sq ft ALON® window blanks for armor applications; and scale up to even larger, high optical quality blanks for Recce window applications is underway. Surmet also produces spinel for customers that require superior transmission at the longer wavelengths in the mid wave infra-red (MWIR). Spinel windows have been limited to smaller sizes than have been achieved with ALON. To date the largest spinel window produced is 11x18-in, and windows 14x20-in size are currently in process. Surmet is now scaling up its spinel processing capability to produce high quality window blanks as large as 19x27-in for sensor applications.

Developmental Toxicology##

EPA Science Inventory

Developmental toxicology encompasses the study of developmental exposures, pharmacokinetics, mechanisms, pathogenesis, and outcomes potentially leading to adverse health effects. Manifestations of developmental toxicity include structural malformations, growth retardation, functi...

Narrow Networks on the Individual Marketplace in 2017.

PubMed

Polski, Daniel; Weiner, Janet; Zhang, Yuehan

2017-09-01

This Issue Brief describes the breadth of physician networks on the ACA marketplaces in 2017. We find that the overall rate of narrow networks is 21%, which is a decline since 2014 (31%) and 2016 (25%). Narrow networks are concentrated in plans sold on state-based marketplaces, at 42%, compared to 10% of plans on federally-facilitated marketplaces. Issuers that have traditionally offered Medicaid coverage have the highest prevalence of narrow network plans at 36%, with regional/local plans and provider-based plans close behind at 27% and 30%. We also find large differences in narrow networks by state and by plan type.

Highly Insulating Windows Volume Purchase Program Final Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2013-04-01

This report documents the development, execution outcomes and lessons learned of the Highly Insulating Windows Volume Purchase (WVP) Program carried out over a three-year period from 2009 through 2012. The primary goals of the program were met: 1) reduce the incremental cost of highly insulating windows compared to ENERGY STAR windows; and 2) raise the public and potential buyers’ awareness of highly insulating windows and their benefits. A key outcome of the program is that the 2013 ENERGY STAR Most Efficient criteria for primary residential windows were adopted from the technical specifications set forth in the WVP program.

The water vapour continuum in near-infrared windows - Current understanding and prospects for its inclusion in spectroscopic databases

NASA Astrophysics Data System (ADS)

Shine, Keith P.; Campargue, Alain; Mondelain, Didier; McPheat, Robert A.; Ptashnik, Igor V.; Weidmann, Damien

2016-09-01

Spectroscopic catalogues, such as GEISA and HITRAN, do not yet include information on the water vapour continuum that pervades visible, infrared and microwave spectral regions. This is partly because, in some spectral regions, there are rather few laboratory measurements in conditions close to those in the Earth's atmosphere; hence understanding of the characteristics of the continuum absorption is still emerging. This is particularly so in the near-infrared and visible, where there has been renewed interest and activity in recent years. In this paper we present a critical review focusing on recent laboratory measurements in two near-infrared window regions (centred on 4700 and 6300 cm-1) and include reference to the window centred on 2600 cm-1 where more measurements have been reported. The rather few available measurements, have used Fourier transform spectroscopy (FTS), cavity ring down spectroscopy, optical-feedback - cavity enhanced laser spectroscopy and, in very narrow regions, calorimetric interferometry. These systems have different advantages and disadvantages. Fourier Transform Spectroscopy can measure the continuum across both these and neighbouring windows; by contrast, the cavity laser techniques are limited to fewer wavenumbers, but have a much higher inherent sensitivity. The available results present a diverse view of the characteristics of continuum absorption, with differences in continuum strength exceeding a factor of 10 in the cores of these windows. In individual windows, the temperature dependence of the water vapour self-continuum differs significantly in the few sets of measurements that allow an analysis. The available data also indicate that the temperature dependence differs significantly between different near-infrared windows. These pioneering measurements provide an impetus for further measurements. Improvements and/or extensions in existing techniques would aid progress to a full characterisation of the continuum - as an example, we

climwin: An R Toolbox for Climate Window Analysis.

PubMed

Bailey, Liam D; van de Pol, Martijn

2016-01-01

When studying the impacts of climate change, there is a tendency to select climate data from a small set of arbitrary time periods or climate windows (e.g., spring temperature). However, these arbitrary windows may not encompass the strongest periods of climatic sensitivity and may lead to erroneous biological interpretations. Therefore, there is a need to consider a wider range of climate windows to better predict the impacts of future climate change. We introduce the R package climwin that provides a number of methods to test the effect of different climate windows on a chosen response variable and compare these windows to identify potential climate signals. climwin extracts the relevant data for each possible climate window and uses this data to fit a statistical model, the structure of which is chosen by the user. Models are then compared using an information criteria approach. This allows users to determine how well each window explains variation in the response variable and compare model support between windows. climwin also contains methods to detect type I and II errors, which are often a problem with this type of exploratory analysis. This article presents the statistical framework and technical details behind the climwin package and demonstrates the applicability of the method with a number of worked examples.

Jaw-phonatory coordination in chronic developmental stuttering.

PubMed

Loucks, Torrey M J; De Nil, Luc F; Sasisekaran, Jayanthi

2007-01-01

A deficiency in sensorimotor integration in a person who stutters may be a factor in the pathophysiology of developmental stuttering. To test oral sensorimotor function in adults who stutter, we used a task that requires the coordination of a jaw-opening movement with phonation onset. The task was adapted from previous limb coordination studies, which show that movement coordination depends on intact proprioception. We hypothesized that adult stutterers would show deficient jaw-phonatory coordination relative to control participants. The task required initiation of phonation as a jaw-opening movement passed through a narrow spatial target. Target amplitude and jaw movement speed were varied. The stuttering group showed significantly higher movement error and spatial variability in jaw-phonatory coordination compared to the control group, but group differences in movement velocity or duration were not found. The aberrant jaw-phonatory coordination of the stuttering participants suggests that stuttering is associated with an oral proprioceptive limitation, although, the findings are also consistent with a motor control deficit. As a result of this activity, reader will (1) learn about a hypothesis and evidence supporting the view that a sensorimotor deficit contributes to chronic developmental stuttering and (2) will obtain information about the role of proprioception in multi-articulatory coordination and how it can be tested using an oral-phonatory coordination task.

Noise Transmission Characteristics of Damped Plexiglas Windows

NASA Technical Reports Server (NTRS)

Gibbs, Gary P.; Buehrle, Ralph D.; Klos, Jacob; Brown, Sherilyn A.

2002-01-01

Most general aviation aircraft utilize single layer plexiglas material for the windshield and side windows. Adding noise control treatments to transparent panels is a challenging problem. In this paper, damped plexiglas windows are evaluated for replacement of conventional windows in general aviation aircraft to reduce the structure-borne and airborne noise transmitted into the interior. In contrast to conventional solid windows, the damped plexiglas window panels are fabricated using two or three layers of plexiglas with transparent viscoelastic damping material sandwiched between the layers. Results from acoustic tests conducted in the NASA Langley Structural Acoustic Loads and Transmission (SALT) facility are used to compare different designs of the damped plexiglas panels with solid windows of the same nominal thickness. Comparisons of the solid and damped plexiglas panels show reductions in the radiated sound power of up to 8 dB at low frequency resonances and as large as 4.5 dB over a 4000 Hz bandwidth. The weight of the viscoelastic treatment was approximately 1% of the panel mass. Preliminary FEM/BEM modeling shows good agreement with experimental results for radiated sound power.

Windowed multipole for cross section Doppler broadening

NASA Astrophysics Data System (ADS)

Josey, C.; Ducru, P.; Forget, B.; Smith, K.

2016-02-01

This paper presents an in-depth analysis on the accuracy and performance of the windowed multipole Doppler broadening method. The basic theory behind cross section data is described, along with the basic multipole formalism followed by the approximations leading to windowed multipole method and the algorithm used to efficiently evaluate Doppler broadened cross sections. The method is tested by simulating the BEAVRS benchmark with a windowed multipole library composed of 70 nuclides. Accuracy of the method is demonstrated on a single assembly case where total neutron production rates and 238U capture rates compare within 0.1% to ACE format files at the same temperature. With regards to performance, clock cycle counts and cache misses were measured for single temperature ACE table lookup and for windowed multipole. The windowed multipole method was found to require 39.6% more clock cycles to evaluate, translating to a 7.9% performance loss overall. However, the algorithm has significantly better last-level cache performance, with 3 fewer misses per evaluation, or a 65% reduction in last-level misses. This is due to the small memory footprint of the windowed multipole method and better memory access pattern of the algorithm.

A note on windowing for the waveform relaxation

NASA Technical Reports Server (NTRS)

Zhang, Hong

1994-01-01

The technique of windowing has been often used in the implementation of the waveform relaxations for solving ODE's or time dependent PDE's. Its efficiency depends upon problem stiffness and operator splitting. Using model problems, the estimates for window length and convergence rate are derived. The electiveness of windowing is then investigated for non-stiff and stiff cases respectively. lt concludes that for the former, windowing is highly recommended when a large discrepancy exists between the convergence rate on a time interval and the ones on its subintervals. For the latter, windowing does not provide any computational advantage if machine features are disregarded. The discussion is supported by experimental results.

Pilot case-control study of paediatric falls from windows.

PubMed

Johnston, Brian D; Quistberg, D Alexander; Shandro, Jamie R; Partridge, Rebecca L; Song, Hyun Rae; Ebel, Beth E

2011-12-01

Unintentional falls from windows are an important cause of paediatric morbidity. There have been no controlled studies to identify modifiable environmental risk factors for window falls in young children. The authors have piloted a case-control study to test procedures for case identification, subject enrolment, and environmental data collection. Case windows were identified when a child 0-9 years old presented for care after a fall from that window. Control windows were identified (1) from the child's home and (2) from the home of an age- and gender-matched child seeking care for an injury diagnosis not related to a window fall. Study staff visited enrolled homes to collect window measurements and conduct window screen performance tests. The authors enrolled and collected data on 18 case windows, 18 in-home controls, and 14 matched community controls. Six potential community controls were contacted for every one enrolled. Families who completed the home visit viewed study procedures positively. Case windows were more likely than community controls to be horizontal sliders (100% vs 50%), to have deeper sills (6.28 vs 4.31 inches), to be higher above the exterior surface (183 vs 82 inches), and to have screens that failed below a threshold derived from the static pressure of a 3-year-old leaning against the mesh (60.0% vs 16.7%). Case windows varied very little from in-home controls. Case-control methodology can be used to study risk factors for paediatric falls from windows. Recruitment of community controls is challenging but essential, because in-home controls tend to be over-matched on important variables. A home visit allows direct measurement of window type, height, sill depth, and screen performance. These variables should all be investigated in subsequent, larger studies covering major housing markets.

Biochemical basis for pharmacological intervention as a reprogramming strategy against hypertension and kidney disease of developmental origin.

PubMed

Tain, You-Lin; Chan, Samuel H H; Chan, Julie Y H

2018-07-01

The concept of "developmental origins of health and disease" (DOHaD) stipulates that both hypertension and kidney disease may take origin from early-life insults. The DOHaD concept also offers reprogramming strategies aiming at shifting therapeutic interventions from adulthood to early life, even before clinical symptoms are evident. Based on those two concepts, this review will present the evidence for the existence of, and the programming mechanisms in, kidney developmental programming that may lead to hypertension and kidney disease. This will be followed by potential pharmacological interventions that may serve as a reprogramming strategy to counter the rising epidemic of hypertension and kidney disease. We point out that before patients could benefit from this strategy, the most pressing issue is for the growing body of evidence from animal studies in support of pharmacological intervention as a reprogramming strategy to long-term protect against hypertension and kidney disease of developmental origins to be validated clinically and the critical window, drug dose, dosing regimen, and therapeutic duration identified. Copyright © 2018 Elsevier Inc. All rights reserved.

Sound transmission loss of windows on high speed trains

NASA Astrophysics Data System (ADS)

Zhang, Yumei; Xiao, Xinbiao; Thompson, David; Squicciarini, Giacomo; Wen, Zefeng; Li, Zhihui; Wu, Yue

2016-09-01

The window is one of the main components of the high speed train car body structure through which noise can be transmitted. To study the windows’ acoustic properties, the vibration of one window of a high speed train has been measured for a running speed of 250 km/h. The corresponding interior noise and the noise in the wheel-rail area have been measured simultaneously. The experimental results show that the window vibration velocity has a similar spectral shape to the interior noise. Interior noise source identification further indicates that the window makes a contribution to the interior noise. Improvement of the window's Sound Transmission Loss (STL) can reduce the interior noise from this transmission path. An STL model of the window is built based on wave propagation and modal superposition methods. From the theoretical results, the window's STL property is studied and several factors affecting it are investigated, which provide indications for future low noise design of high speed train windows.

Use of UV-protective windows and window films to aid in the prevention of skin cancer.

PubMed

Edlich, Richard F; Winters, Kathryne L; Cox, Mary Jude; Becker, Daniel G; Horowitz, Jed H; Nichter, Larry S; Britt, L D; Long, William B; Edlic, Elizabeth C

2004-01-01

People are exposed to ambient solar ultraviolet (UV) radiation throughout their daily routine, intentionally and unintentionally. Cumulative and excessive exposure to UV radiation is the behavioral cause to skin cancers, skin damage, premature skin aging, and sun-related eye disorders. More than one million new cases of skin cancer were diagnosed in the United States this year. UV radiates directly and diffusely scattered by the various environmental and atmospheric conditions and has access to the skin from all directions. Because of this diffuse UV radiation, a person situated under a covering, such as the roof of a car or house, is not completely protected from the sun's rays. Because shade structures do not protect effectively against UV radiation, there have been major advances in photoprotection of glass by the development of specially designed photoprotective windows and films. It is the purpose of this collective review to highlight the photoprotective windows and films that should be incorporated into residential, commercial, and school glass windows to reduce sun exposure. Low-emittence (low-E) coatings are microscopically thin, virtually invisible, metal or metallic oxide layers deposited on a window or skylight glazing surface to reduce the U-factor by suppressing radiative heat flow as well as to limit UV radiation. The exclusive Thermaflect coating uses the most advanced, double-layer soft coat technology to continue to deliver top performance for UV protection as well as prevent heat loss in the home. This product blocks 87% of UV radiation and has an Energy Star certification in all climate zones. Tints and films have been another important advance in glass photoprotection, especially in automobiles. Quality widow film products are high-tech laminates of polyester and metallized coatings bonded by distortion-free adhesives. The International Window Film Association provides members with accreditation in solar control films, safety films, and

NREL Electrochromic Window Research Wins Award

ScienceCinema

None

2017-12-09

Winners of the CO-LABS Governor's Award for High-Impact Research in Energy Efficiency, Dr. Satyen Deb at the U.S. Department of Energy's National Renewable Energy Laboratory (NREL) discovered that a small electrical charge can change the opacity of tungsten oxide from clear to tinted. He, Dr. Dane Gillaspie, and their fellow scientists at NREL then applied this knowledge to develop and transfer the technologies required to construct an electrochromic window, which can switch between clear and heavily tinted states. Electrochromic windows allow natural light in while adding tint to reduce summer heat and glare, and going clear to allow sunlight through in the winter. Broad adaptation of these windows could reduce US total energy use by four percent and reduce building cooling loads by 20%, much of this during expensive peak hours. Windows based on these discoveries are now being installed worldwide.

UV conformal window for asymptotic safety

NASA Astrophysics Data System (ADS)

Bond, Andrew D.; Litim, Daniel F.; Vazquez, Gustavo Medina; Steudtner, Tom

2018-02-01

Interacting fixed points in four-dimensional gauge theories coupled to matter are investigated using perturbation theory up to three loop order. It is shown how fixed points, scaling exponents, and anomalous dimensions are obtained as a systematic power series in a small parameter. The underlying ordering principle is explained and contrasted with conventional perturbation theory and Weyl consistency conditions. We then determine the conformal window with asymptotic safety from the complete next-to-next-to-leading order in perturbation theory. Limits for the conformal window arise due to fixed point mergers, the onset of strong coupling, or vacuum instability. A consistent picture is uncovered by comparing various levels of approximation. The theory remains perturbative in the entire conformal window, with vacuum stability dictating the tightest constraints. We also speculate about a secondary conformal window at strong coupling and estimate its lower limit. Implications for model building and cosmology are indicated.

Computerized tomography magnified bone windows are superior to standard soft tissue windows for accurate measurement of stone size: an in vitro and clinical study.

PubMed

Eisner, Brian H; Kambadakone, Avinash; Monga, Manoj; Anderson, James K; Thoreson, Andrew A; Lee, Hang; Dretler, Stephen P; Sahani, Dushyant V

2009-04-01

We determined the most accurate method of measuring urinary stones on computerized tomography. For the in vitro portion of the study 24 calculi, including 12 calcium oxalate monohydrate and 12 uric acid stones, that had been previously collected at our clinic were measured manually with hand calipers as the gold standard measurement. The calculi were then embedded into human kidney-sized potatoes and scanned using 64-slice multidetector computerized tomography. Computerized tomography measurements were performed at 4 window settings, including standard soft tissue windows (window width-320 and window length-50), standard bone windows (window width-1120 and window length-300), 5.13x magnified soft tissue windows and 5.13x magnified bone windows. Maximum stone dimensions were recorded. For the in vivo portion of the study 41 patients with distal ureteral stones who underwent noncontrast computerized tomography and subsequently spontaneously passed the stones were analyzed. All analyzed stones were 100% calcium oxalate monohydrate or mixed, calcium based stones. Stones were prospectively collected at the clinic and the largest diameter was measured with digital calipers as the gold standard. This was compared to computerized tomography measurements using 4.0x magnified soft tissue windows and 4.0x magnified bone windows. Statistical comparisons were performed using Pearson's correlation and paired t test. In the in vitro portion of the study the most accurate measurements were obtained using 5.13x magnified bone windows with a mean 0.13 mm difference from caliper measurement (p = 0.6). Measurements performed in the soft tissue window with and without magnification, and in the bone window without magnification were significantly different from hand caliper measurements (mean difference 1.2, 1.9 and 1.4 mm, p = 0.003, <0.001 and 0.0002, respectively). When comparing measurement errors between stones of different composition in vitro, the error for calcium oxalate

Ring resonator based narrow-linewidth semiconductor lasers

NASA Technical Reports Server (NTRS)

Ksendzov, Alexander (Inventor)

2005-01-01

The present invention is a method and apparatus for using ring resonators to produce narrow linewidth hybrid semiconductor lasers. According to one embodiment of the present invention, the narrow linewidths are produced by combining the semiconductor gain chip with a narrow pass band external feedback element. The semi conductor laser is produced using a ring resonator which, combined with a Bragg grating, acts as the external feedback element. According to another embodiment of the present invention, the proposed integrated optics ring resonator is based on plasma enhanced chemical vapor deposition (PECVD) SiO.sub.2 /SiON/SiO.sub.2 waveguide technology.

A developmental perspective on the link between parents' employment and children's obesity.

PubMed

Crosnoe, Robert; Dunifon, Rachel

2017-01-01

Despite public concerns about the negative implications of the increased labor force participation of mothers for child development, decades of research have revealed few risks and some benefits. One potential risk-a consistently observed association between maternal employment and childhood obesity-offers a window into how some dimensions of family health may be undermined by work in an economic and policy context that is not family friendly. The purpose of this article is to identify ways that a developmental perspective can enrich the literature on how children's weight may be related to the work experiences of both mothers and fathers across diverse populations, a literature that heretofore has been dominated by economic and demographic perspectives, focused almost solely on women, and largely ignored racial/ethnic variation. After reviewing the extant literature, we put forward a conceptual model that uses ecological and developmental insights to identify the mechanisms by which parents' employment might matter to children's weight and discuss this model in the context of the contemporary landscape of family policy. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Consensus statement on round window vibroplasty.

PubMed

Beltrame, Achille M; Todt, Ingo; Sprinzl, Georg; Profant, Milan; Schwab, Burkhard

2014-10-01

This study aimed to review current knowledge regarding implantation of the Vibrant Soundbridge floating mass transducer (FMT) at the round window (round window vibroplasty) as well as to form a consensus on steps for a reliable, stable surgical procedure. Review of the literature and experimental observations by the authors. Round window (RW) vibroplasty has been established as a reliable procedure that produces good and stable results for patients with conductive or mixed hearing loss. The experience gained over the past few years of the authors' more than 200 implantations has led to consensus on several key points: (1) a wide and bloodless access to the middle ear with facial nerve monitoring, (2) the careful and correct identification and exposure of the round window membrane, (3) a good setup for efficient energy transition of the FMT, namely, perpendicular placement of the FMT with no contact to bone and the placement of cartilage behind the FMT to create a preloaded "spring" function, and (4) 4 points of FMT fixation: a rim of the round window bony overhang left intact both anterior and posterior to the FMT, conductor link stabilization, and cartilage behind the FMT. In addition, the FMT should be covered with soft tissue. © The Author(s) 2014.

Ocular Biometrics of Myopic Eyes With Narrow Angles.

PubMed

Chong, Gabriel T; Wen, Joanne C; Su, Daniel Hsien-Wen; Stinnett, Sandra; Asrani, Sanjay

2016-02-01

The purpose of this study was to compare the ocular biometrics between myopic patients with and without narrow angles. Patients with a stable myopic refraction (myopia worse than -1.00 D spherical equivalent) were prospectively recruited. Angle status was assessed using gonioscopy and biometric measurements were performed using an anterior segment optical coherence tomography and an IOLMaster. A total of 29 patients (58 eyes) were enrolled with 13 patients (26 eyes) classified as having narrow angles and 16 patients (32 eyes) classified as having open angles. Baseline demographics of age, sex, and ethnicity did not differ significantly between the 2 groups. The patients with narrow angles were on average older than those with open angles but the difference did not reach statistical significance (P=0.12). The central anterior chamber depth was significantly less in the eyes with narrow angles (P=0.05). However, the average lens thickness, although greater in the eyes with narrow angles, did not reach statistical significance (P=0.10). Refractive error, axial lengths, and iris thicknesses did not differ significantly between the 2 groups (P=0.32, 0.47, 0.15). Narrow angles can occur in myopic eyes. Routine gonioscopy is therefore recommended for all patients regardless of refractive error.

Intramyocardial arterial narrowing in dogs with subaortic stenosis.

PubMed

Falk, T; Jönsson, L; Pedersen, H D

2004-09-01

Earlier studies have described intramyocardial arterial narrowing based on hyperplasia and hypertrophy of the vessel wall in dogs with subaortic stenosis (SAS). In theory, such changes might increase the risk of sudden death, as they seem to do in heart disease in other species. This retrospective pathological study describes and quantifies intramyocardial arterial narrowing in 44 dogs with naturally occurring SAS and in eight control dogs. The majority of the dogs with SAS died suddenly (n=27); nine had died or been euthanased with signs of heart failure and eight were euthanased without clinical signs. Dogs with SAS had significantly narrower intramyocardial arteries (P<0.001) and more myocardial fibrosis (P<0.001) than control dogs. Male dogs and those with more severe hypertrophy had more vessel narrowing (P=0.02 and P=0.02, respectively), whereas dogs with dilated hearts had slightly less pronounced arterial thickening (P=0.01). Arterial narrowing was not related to age, but fibrosis increased with age (P=0.047). Dogs that died suddenly did not have a greater number of arterial changes than other dogs with SAS. This study suggests that most dogs with SAS have intramyocardial arterial narrowing and that the risk of dying suddenly is not significantly related to the overall degree of vessel obliteration.

Designing prospective cohort studies for assessing reproductive and developmental toxicity during sensitive windows of human reproduction and development--the LIFE Study.

PubMed

Buck Louis, Germaine M; Schisterman, Enrique F; Sweeney, Anne M; Wilcosky, Timothy C; Gore-Langton, Robert E; Lynch, Courtney D; Boyd Barr, Dana; Schrader, Steven M; Kim, Sungduk; Chen, Zhen; Sundaram, Rajeshwari

2011-09-01

The relationship between the environment and human fecundity and fertility remains virtually unstudied from a couple-based perspective in which longitudinal exposure data and biospecimens are captured across sensitive windows. In response, we completed the LIFE Study with methodology that intended to empirically evaluate a priori purported methodological challenges: implementation of population-based sampling frameworks suitable for recruiting couples planning pregnancy; obtaining environmental data across sensitive windows of reproduction and development; home-based biospecimen collection; and development of a data management system for hierarchical exposome data. We used two sampling frameworks (i.e., fish/wildlife licence registry and a direct marketing database) for 16 targeted counties with presumed environmental exposures to persistent organochlorine chemicals to recruit 501 couples planning pregnancies for prospective longitudinal follow-up while trying to conceive and throughout pregnancy. Enrolment rates varied from <1% of the targeted population (n = 424,423) to 42% of eligible couples who were successfully screened; 84% of the targeted population could not be reached, while 36% refused screening. Among enrolled couples, ∼ 85% completed daily journals while trying; 82% of pregnant women completed daily early pregnancy journals, and 80% completed monthly pregnancy journals. All couples provided baseline blood/urine samples; 94% of men provided one or more semen samples and 98% of women provided one or more saliva samples. Women successfully used urinary fertility monitors for identifying ovulation and home pregnancy test kits. Couples can be recruited for preconception cohorts and will comply with intensive data collection across sensitive windows. However, appropriately sized sampling frameworks are critical, given the small percentage of couples contacted found eligible and reportedly planning pregnancy at any point in time. © Published 2011. This

Novel windowing technique realized in FPGA for radar system

NASA Astrophysics Data System (ADS)

Escamilla-Hernandez, E.; Kravchenko, V. F.; Ponomaryov, V. I.; Ikuo, Arai

2006-02-01

To improve the weak target detection ability in radar applications a pulse compression is usually used that in the case linear FM modulation can improve the SNR. One drawback in here is that it can add the range side-lobes in reflectivity measurements. Using weighting window processing in time domain it is possible to decrease significantly the side-lobe level (SLL) and resolve small or low power targets those are masked by powerful ones. There are usually used classical windows such as Hamming, Hanning, etc. in window processing. Additionally to classical ones in this paper we also use a novel class of windows based on atomic functions (AF) theory. For comparison of simulation and experimental results we applied the standard parameters, such as coefficient of amplification, maximum level of side-lobe, width of main lobe, etc. To implement the compression-windowing model on hardware level it has been employed FPGA. This work aims at demonstrating a reasonably flexible implementation of FM-linear signal, pulse compression and windowing employing FPGA's. Classical and novel AF window technique has been investigated to reduce the SLL taking into account the noise influence and increasing the detection ability of the small or weak targets in the imaging radar. Paper presents the experimental hardware results of windowing in pulse compression radar resolving several targets for rectangular, Hamming, Kaiser-Bessel, (see manuscript for formula) functions windows. The windows created by use the atomic functions offer sufficiently better decreasing of the SLL in case of noise presence and when we move away of the main lobe in comparison with classical windows.

Temporal Binding Window of the Sound-Induced Flash Illusion in Amblyopia.

PubMed

Narinesingh, Cindy; Goltz, Herbert C; Wong, Agnes M F

2017-03-01

Amblyopia is a neurodevelopmental visual disorder caused by abnormal visual experience in childhood. In addition to known visual deficits, there is evidence for changes in audiovisual integration in amblyopia using explicit tasks. We examined audiovisual integration in amblyopia using an implicit task that is more relevant in a real-world context. A total of 11 participants with amblyopia and 16 controls were tested binocularly and monocularly on the sound-induced flash illusion, in which flashes and beeps are presented concurrently and the perceived number of flashes is influenced by the number of beeps. The task used 1 to 2 rapid peripheral flashes presented with 0 to 2 beeps, at 5 stimulus onset asynchronies, that is, beep (-200 milliseconds, -100 milliseconds) or flash leading (100 milliseconds, 200 milliseconds) or simultaneous (0 milliseconds). Participants reported the number of perceived flashes. Susceptibility was indicated by a "2 flashes" response to "fission" (1 flash, 2 beeps) or "1 flash" to "fusion" (2 flashes, 1 beep). For fission with the beep leading during binocular viewing, controls showed an expected decrease in illusion strength as stimulus onset asynchronies increased, whereas the illusion strength remained constant in participants with amblyopia, indicating a wider temporal binding window in amblyopia (P = 0.007). For fusion, participants with amblyopia showed reduced illusion strength during amblyopic eye viewing (P = 0.044) with the flash leading. Amblyopia is associated with the widening of the temporal binding window, specifically for fission when viewing binocularly with the beep leading. This suggests a developmental adaptation to delayed amblyopic eye visual processing to optimize audiovisual integration.

Large Acrylic Spherical Windows In Hyperbaric Underwater Photography

NASA Astrophysics Data System (ADS)

Lones, Joe J.; Stachiw, Jerry D.

1983-10-01

Both acrylic plastic and glass are common materials for hyperbaric optical windows. Although glass continues to be used occasionally for small windows, virtually all large viewports are made of acrylic. It is easy to uderstand the wide use of acrylic when comparing design properties of this plastic with those of glass, and glass windows are relatively more difficult to fabricate and use. in addition there are published guides for the design and fabrication of acrylic windows to be used in the hyperbaric environment of hydrospace. Although these procedures for fabricating the acrylic windows are somewhat involved, the results are extremely reliable. Acrylic viewports are now fabricated to very large sizes for manned observation or optical quality instrumen tation as illustrated by the numerous acrylic submersible vehicle hulls for hu, an occupancy currently in operation and a 3600 large optical window recently developed for the Walt Disney Circle Vision under-water camera housing.

Eco-Evo-Devo: developmental symbiosis and developmental plasticity as evolutionary agents.

PubMed

Gilbert, Scott F; Bosch, Thomas C G; Ledón-Rettig, Cristina

2015-10-01

The integration of research from developmental biology and ecology into evolutionary theory has given rise to a relatively new field, ecological evolutionary developmental biology (Eco-Evo-Devo). This field integrates and organizes concepts such as developmental symbiosis, developmental plasticity, genetic accommodation, extragenic inheritance and niche construction. This Review highlights the roles that developmental symbiosis and developmental plasticity have in evolution. Developmental symbiosis can generate particular organs, can produce selectable genetic variation for the entire animal, can provide mechanisms for reproductive isolation, and may have facilitated evolutionary transitions. Developmental plasticity is crucial for generating novel phenotypes, facilitating evolutionary transitions and altered ecosystem dynamics, and promoting adaptive variation through genetic accommodation and niche construction. In emphasizing such non-genomic mechanisms of selectable and heritable variation, Eco-Evo-Devo presents a new layer of evolutionary synthesis.

Multilayered microelectronic device package with an integral window

DOEpatents

Peterson, Kenneth A.; Watson, Robert D.

2003-01-01

An apparatus for packaging of microelectronic devices is disclosed, wherein the package includes an integral window. The microelectronic device can be a semiconductor chip, a CCD chip, a CMOS chip, a VCSEL chip, a laser diode, a MEMS device, or a IMEMS device. The package can comprise, for example, a cofired ceramic frame or body. The package has an internal stepped structure made of a plurality of plates, with apertures, which are patterned with metallized conductive circuit traces. The microelectronic device can be flip-chip bonded on the plate to these traces, and oriented so that the light-sensitive side is optically accessible through the window. A cover lid can be attached to the opposite side of the package. The result is a compact, low-profile package, having an integral window that can be hermetically-sealed. The package body can be formed by low-temperature cofired ceramic (LTCC) or high-temperature cofired ceramic (HTCC) multilayer processes with the window being simultaneously joined (e.g. cofired) to the package body during LTCC or HTCC processing. Multiple chips can be located within a single package, according to some embodiments. The cover lid can include a window. The apparatus is particularly suited for packaging of MEMS devices, since the number of handling steps is greatly reduced, thereby reducing the potential for contamination. The integral window can further include a lens for optically transforming light passing through the window. The package can include an array of binary optic lenslets made integral with the window. The package can include an electrically-switched optical modulator, such as a lithium niobate window attached to the package, for providing a very fast electrically-operated shutter.

Weibull Analysis and Area Scaling for Infrared Window Materials (U)

DTIC Science & Technology

2016-08-01

the strength of a window scales inversely with the size of the window. This report was reviewed for technical accuracy by Howard Poisl, Thomas M...strength of a window scales inversely with the size of the window. Test data are given for aluminum oxynitride (ALON), calcium fluoride, chemical vapor...failure of an optical window in the absence of slow crack growth. This report illustrates how the strength of a window scales inversely with the size of

Mind the Gap: Summary of Window Residential Retrofit Solutions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Petersen, Joseph M.; Cort, Katherine A.; Widder, Sarah H.

Improving the insulation, solar heat gain, and infiltration characteristics of windows in a home has the potential to significantly improve the overall thermal performance by reducing heat transfer through the window and also by decreasing infiltration of outdoor air into the home. As approximately 43% of existing homes still have single-pane clear windows (~50 million houses) and millions of other homes have only double-pane clear windows (Cort 2013), improving window performance also presents a significant opportunity for energy savings in the residential sector. Today, various energy-saving window retrofit opportunities are available to homeowners, ranging from window coverings and storm panelsmore » to highly-insulating triple-pane R-5 window replacements. Many of these technologies have been evaluated in the field, in the “Lab Homes” at Pacific Northwest National Laboratory, and through modeling to prove their cost-effectiveness and performance in different climate regions. Recently, the Pacific Northwest’s Regional Technical Forum approved a utility measure for low- emissivity storm windows based on such data. This action represents a watershed moment for increasing the variety and prevalence of fenestration options in utility programs, especially for the low-income demographic. This paper will review various window retrofit options, the most recent field test and modeling data regarding their performance and cost-effectiveness, and discuss future rating efforts. This information is useful for utilities and energy-efficiency program managers to help effectively implement incentive measures for these technologies.« less

Multisensory integration and ADHD-like traits: Evidence for an abnormal temporal integration window in ADHD.

PubMed

Panagiotidi, Maria; Overton, Paul G; Stafford, Tom

2017-11-01

Abnormalities in multimodal processing have been found in many developmental disorders such as autism and dyslexia. However, surprisingly little empirical work has been conducted to test the integrity of multisensory integration in Attention Deficit Hyperactivity Disorder (ADHD). The main aim of the present study was to examine links between symptoms of ADHD (as measured using a self-report scale in a healthy adult population) and the temporal aspects of multisensory processing. More specifically, a Simultaneity Judgement (SJ) and a Temporal Order Judgement (TOJ) task were used in participants with low and high levels of ADHD-like traits to measure the temporal integration window and Just-Noticeable Difference (JND) (respectively) between the timing of an auditory beep and a visual pattern presented over a broad range of stimulus onset asynchronies. The Point of Subjective Similarity (PSS) was also measured in both cases. In the SJ task, participants with high levels of ADHD-like traits considered significantly fewer stimuli to be simultaneous than participants with high levels of ADHD-like traits, and the former were found to have significantly smaller temporal windows of integration (although no difference was found in the PSS in the SJ or TOJ tasks, or the JND in the latter). This is the first study to identify an abnormal temporal integration window in individuals with ADHD-like traits. Perceived temporal misalignment of two or more modalities can lead to distractibility (e.g., when the stimulus components from different modalities occur separated by too large of a temporal gap). Hence, an abnormality in the perception of simultaneity could lead to the increased distractibility seen in ADHD. Copyright © 2017 Elsevier B.V. All rights reserved.

Narrow-linewidth Q-switched random distributed feedback fiber laser.

PubMed

Xu, Jiangming; Ye, Jun; Xiao, Hu; Leng, Jinyong; Wu, Jian; Zhang, Hanwei; Zhou, Pu

2016-08-22

A narrow-linewidth Q-switched random fiber laser (RFL) based on a half-opened cavity, which is realized by narrow-linewidth fiber Bragg grating (FBG) and a section of 3 km passive fiber, has been proposed and experimentally investigated. The narrow-linewidth lasing is generated by the spectral filtering of three FBGs with linewidth of 1.21 nm, 0.56 nm, and 0.12 nm, respectively. The Q switching of the distributed cavity is achieved by placing an acousto-optical modulator (AOM) between the FBG and the passive fiber. The maximal output powers of the narrow-linewidth RFLs with the three different FBGs are 0.54 W, 0.27 W, and 0.08 W, respectively. Furthermore, the repetition rates of the output pulses are 500 kHz, and the pulse durations are about 500 ns. The corresponding pulse energies are about 1.08 μJ, 0.54 μJ, and 0.16 μJ, accordingly. The linewidth of FBG can influence the output characteristics in full scale. The narrower the FBG, the higher the pump threshold; the lower the output power at the same pump level, the more serious the linewidth broadening; and thus the higher the proportion of the CW-ground exists in the output pulse trains. Thanks to the assistance of the band-pass filter (BPF), the proportion of the CW-ground of narrow-linewidth Q-switched RFL under the relative high-pump-low-output condition can be reduced effectively. The experimental results indicate that it is challenging to demonstrate a narrow-linewidth Q-switched RFL with high quality output. But further power scaling and linewidth narrowing is possible in the case of operating parameters, optimization efforts, and a more powerful pump source. To the best of our knowledge, this is the first demonstration of narrow-linewidth generation in a Q-switched RFL.

The rarefaction wave propagation in transparent windows

NASA Astrophysics Data System (ADS)

Glam, B.; Porat, E.; Horovitz, Y.; Yosef-Hai, A.

2017-01-01

The radial (lateral) rarefaction wave velocity of polymethyl methacrylate (PMMA) and Lithium Fluoride (LiF) windows were studied by plate impact experiments that were carried out at Soreq NRC up to a pressure of 146 kbar in the PMMA and 334 kbar in the LiF. The windows were glued to Lead targets that were impacted by a copper impactor. The VISAR measurement was done in the window interface with the target. This information was utilized to identify the radial rarefaction arrival time at the center of different diameter windows after the shock event, and served as a measurement to the radial wave velocity in the shocked material. It was found that for both windows, LiF or PMMA, the measured radial wave velocity increases with the pressure. Furthermore, this velocity is significantly higher compared to the expected longitudinal sound velocity at the same pressure, calculated by the Steinberg EOS in the PMMA and by ab initio calculation in the LiF. Here we present the experimental results and a comparison with analytical calculation of the sound velocity using the Steinberg EOS.

Bispectral analysis: comparison of two windowing functions

NASA Astrophysics Data System (ADS)

Silvagni, D.; Djerroud, C.; Réveillé, T.; Gravier, E.

2018-02-01

Amongst all the normalized forms of bispectrum, the bicoherence is shown to be a very useful diagnostic tool in experimental studies of nonlinear wave interactions in plasma, as it measures the fraction of wave power due to the quadratic wave coupling in a self-excited fluctuation spectrum [1, 2]. In order to avoid spectral leakage, the application of a windowing function is needed during the bicoherence computation. Spectral leakage from statistically dependent components are of crucial importance in the discrimination between coupled and uncoupled modes, as they will introduce in the bicoherence spectrum phase-coupled modes which in reality do not exist. Therefore, the windowing function plays a key role in the bicoherence estimation. In this paper, two windowing methods are compared: the multiplication of the initial signal by the Hanning function and the subtraction of the straight line which links the two extremities of the signal. The influence of these two windowing methods on both the power spectrum and the bicoherence spectrum is showed. Although both methods give precise results, the Hanning function appears to be the more suitable window.

Discovery of a narrow line quasar

NASA Technical Reports Server (NTRS)

Stocke, J.; Liebert, J.; Maccacaro, T.; Griffiths, R. E.; Steiner, J. E.

1982-01-01

A stellar object is reported which, while having X-ray and optical luminosities typical of quasars, has narrow permitted and forbidden emission lines over the observed spectral range. The narrow-line spectrum is high-excitation, the Balmer lines seem to be recombinational, and a redder optical spectrum than that of most quasars is exhibited, despite detection as a weak radio source. The object does not conform to the relationships between H-beta parameters and X-ray flux previously claimed for a large sample of the active galactic nuclei. Because reddish quasars with narrow lines, such as the object identified, may not be found by the standard techniques for the discovery of quasars, the object may be a prototype of a new class of quasars analogous to high-luminosity Seyfert type 2 galaxies. It is suggested that these objects cannot comprise more than 10% of all quasars.

Infants Experience Perceptual Narrowing for Nonprimate Faces

ERIC Educational Resources Information Center

Simpson, Elizabeth A.; Varga, Krisztina; Frick, Janet E.; Fragaszy, Dorothy

2011-01-01

Perceptual narrowing--a phenomenon in which perception is broad from birth, but narrows as a function of experience--has previously been tested with primate faces. In the first 6 months of life, infants can discriminate among individual human and monkey faces. Though the ability to discriminate monkey faces is lost after about 9 months, infants…

Three-dimensional laser window formation for industrial application

NASA Technical Reports Server (NTRS)

Verhoff, Vincent G.; Kowalski, David

1993-01-01

The NASA Lewis Research Center has developed and implemented a unique process for forming flawless three-dimensional, compound-curvature laser windows to extreme accuracies. These windows represent an integral component of specialized nonintrusive laser data acquisition systems that are used in a variety of compressor and turbine research testing facilities. These windows are molded to the flow surface profile of turbine and compressor casings and are required to withstand extremely high pressures and temperatures. This method of glass formation could also be used to form compound-curvature mirrors that would require little polishing and for a variety of industrial applications, including research view ports for testing devices and view ports for factory machines with compound-curvature casings. Currently, sodium-alumino-silicate glass is recommended for three-dimensional laser windows because of its high strength due to chemical strengthening and its optical clarity. This paper discusses the main aspects of three-dimensional laser window formation. It focuses on the unique methodology and the peculiarities that are associated with the formation of these windows.

Design of the beryllium window for Brookhaven Linac Isotope Producer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nayak, S.; Mapes, M.; Raparia, D.

2015-11-01

In the Brookhaven Linac Isotope Producer (BLIP) beam line, there were two Beryllium (Be) windows with an air gap to separate the high vacuum upstream side from low vacuum downstream side. There had been frequent window failures in the past which affected the machine productivity and increased the radiation dose received by workers due to unplanned maintenance. To improve the window life, design of Be window is reexamined. Detailed structural and thermal simulations are carried out on Be window for different design parameters and loading conditions to come up with better design to improve the window life. The new designmore » removed the air gap and connect the both beam lines with a Be window in-between. The new design has multiple advantages such as 1) reduces the beam energy loss (because of one window with no air gap), 2) reduces air activation due to nuclear radiation and 3) increased the machine reliability as there is no direct pressure load during operation. For quick replacement of this window, an aluminum bellow coupled with load binder was designed. There hasn’t been a single window failure since the new design was implemented in 2012.« less

Stand-alone photovoltaic (PV) powered electrochromic window

DOEpatents

Benson, David K.; Crandall, Richard S.; Deb, Satyendra K.; Stone, Jack L.

1995-01-01

A variable transmittance double pane window includes an electrochromic material that has been deposited on one pane of the window in conjunction with an array of photovoltaic cells deposited along an edge of the pane to produce the required electric power necessary to vary the effective transmittance of the window. A battery is placed in a parallel fashion to the array of photovoltaic cells to allow the user the ability to manually override the system when a desired transmittance is desired.

Stand-alone photovoltaic (PV) powered electrochromic window

DOEpatents

Benson, D.K.; Crandall, R.S.; Deb, S.K.; Stone, J.L.

1995-01-24

A variable transmittance double pane window includes an electrochromic material that has been deposited on one pane of the window in conjunction with an array of photovoltaic cells deposited along an edge of the pane to produce the required electric power necessary to vary the effective transmittance of the window. A battery is placed in a parallel fashion to the array of photovoltaic cells to allow the user the ability to manually override the system when a desired transmittance is desired. 11 figures.

Development of Multispectral Sandwich-Type IR Windows.

DTIC Science & Technology

1977-04-01

Coatings 52 4.4 Thermophyslcal Properties 59 4.5 Mechanical Properties 62 4.5.1 Hardness and Strength of Window Components ... 62 4.5.2 Bond...AR coating ) 51 36 Transmittance vs. wavelength for a 0.050 in. thick CVD ZnS plate (No AR coating ) 53 37 Transmittance of a ZnS/ZnSe composite...compared to 67% calculated for the ZnSe window alone. As described below, anti -reflection coatings deposited onto the composite window will further enhance

Window Performance in Extreme Cold,

DTIC Science & Technology

1982-12-01

outdoor temperatures ranging between -40 and 20*F Alaska that have undergone an extensive window re- as shown in Table 2. We made these observations in...good predictor of when We made icing and condensation observations over moisture or ice would occur on a window pane. the temperature spectrum shown...tions were made during the daytime, it was often likely sashes or frames, and 4) vapor-loose indoor sashes that ATIo at the time of observation would

Nonuniform Effects of Reinstatement within the Time Window

ERIC Educational Resources Information Center

Galluccio, Llissa; Rovee-Collier, Carolyn

2006-01-01

A time window is a limited period after an event initially occurs in which additional information can be integrated with the memory of that event. It shuts when the memory is forgotten. The time window hypothesis holds that the impact of a manipulation at different points within the time window is nonuniform. In two operant conditioning…

Windows Program For Driving The TDU-850 Printer

NASA Technical Reports Server (NTRS)

Parrish, Brett T.

1995-01-01

Program provides WYSIWYG compatibility between video display and printout. PDW is Microsoft Windows printer-driver computer program for use with Raytheon TDU-850 printer. Provides previously unavailable linkage between printer and IBM PC-compatible computers running Microsoft Windows. Enhances capabilities of Raytheon TDU-850 hardcopier by emulating all textual and graphical features normally supported by laser/ink-jet printers and makes printer compatible with any Microsoft Windows application. Also provides capabilities not found in laser/ink-jet printer drivers by providing certain Windows applications with ability to render high quality, true gray-scale photographic hardcopy on TDU-850. Written in C language.

Cooled window for X-rays or charged particles

DOEpatents

Logan, Clinton M.

1996-01-01

A window that provides good structural integrity and a very high capacity for removal of the heat deposited by x-rays, electrons, or ions, with minimum attenuation of the desired beam. The window is cooled by providing microchannels therein through which a coolant is pumped. For example, the window may be made of silicon with etched microchannels therein and covered by a silicon member. A window made of silicon with a total thickness of 520 .mu.m transmits 96% of the x-rays at an energy of 60 keV, and the transmission is higher than 90% for higher energy photons.

A Window of Opportunity for Cognitive Training in Adolescence

PubMed Central

Knoll, Lisa J.; Fuhrmann, Delia; Sakhardande, Ashok L.; Stamp, Fabian; Speekenbrink, Maarten; Blakemore, Sarah-Jayne

2016-01-01

In the current study, we investigated windows for enhanced learning of cognitive skills during adolescence. Six hundred thirty-three participants (11–33 years old) were divided into four age groups, and each participant was randomly allocated to one of three training groups. Each training group completed up to 20 days of online training in numerosity discrimination (i.e., discriminating small from large numbers of objects), relational reasoning (i.e., detecting abstract relationships between groups of items), or face perception (i.e., identifying differences in faces). Training yielded some improvement in performance on the numerosity-discrimination task, but only in older adolescents or adults. In contrast, training in relational reasoning improved performance on that task in all age groups, but training benefits were greater for people in late adolescence and adulthood than for people earlier in adolescence. Training did not increase performance on the face-perception task for any age group. Our findings suggest that for certain cognitive skills, training during late adolescence and adulthood yields greater improvement than training earlier in adolescence, which highlights the relevance of this late developmental stage for education. PMID:27815519

Data in support of energy performance of double-glazed windows.

PubMed

Shakouri, Mahmoud; Banihashemi, Saeed

2016-06-01

This paper provides the data used in a research project to propose a new simplified windows rating system based on saved annual energy ("Developing an empirical predictive energy-rating model for windows by using Artificial Neural Network" (Shakouri Hassanabadi and Banihashemi Namini, 2012) [1], "Climatic, parametric and non-parametric analysis of energy performance of double-glazed windows in different climates" (Banihashemi et al., 2015) [2]). A full factorial simulation study was conducted to evaluate the performance of 26 different types of windows in a four-story residential building. In order to generalize the results, the selected windows were tested in four climates of cold, tropical, temperate, and hot and arid; and four different main orientations of North, West, South and East. The accompanied datasets include the annual saved cooling and heating energy in different climates and orientations by using the selected windows. Moreover, a complete dataset is provided that includes the specifications of 26 windows, climate data, month, and orientation of the window. This dataset can be used to make predictive models for energy efficiency assessment of double glazed windows.

Exclusion of particulate allergens by window air conditioners.

PubMed

Solomon, W R; Burge, H A; Boise, J R

1980-04-01

Effects of window air-conditioner operation on intramural particle levels were assessed in the bedrooms of 20 homes and in 10 outpatient clinic examining rooms during late summer periods. At each site, pollen and spore collections in the mechanically cooled room and a normally ventilated counterpart were compared using volumetric impactors. Substantially lower particle recoveries (median = 16/m3) were found in air-conditioned rooms than in those with open windows alone (median = 253 particles/m3). Furthermore, substantial exclusion of small (e.g., Ganoderma spores) as well as large (ragweed pollens) aerosol components were found by window units. Control studies within normally ventilated rooms and outside their open windows showed a marked but variable inward flux of particles. Window units appear to substantially reduce indoor allergan levels by maintaining the isolation of enclosed spaces from particle-bearing outdoor air.

Cryogenic Detectors (Narrow Field Instruments)

NASA Astrophysics Data System (ADS)

Hoevers, H.; Verhoeve, P.

Two cryogenic imaging spectrometer arrays are currently considered as focal plane instruments for XEUS. The narrow field imager 1 (NFI 1) will cover the energy range from 0.05 to 3 keV with an energy resolution of 2 eV, or better, at 500 eV. A second narrow field imager (NFI 2) covers the energy range from 1 to 15 keV with an energy resolution of 2 eV (at 1 keV) and 5 eV (at 7 keV), creating some overlap with part of the NFI 1 energy window. Both narrow field imagers have a 0.5 arcmin field of view. Their imaging capabilities are matched to the XEUS optics of 2 to 5 arcsec leading to 1 arcsec pixels. The detector arrays will be cooled by a closed cycle system comprising a mechanical cooler with a base temperature of 2.5 K and either a low temperature 3He sorption pump providing the very low temperature stage and/or an Adiabatic Demagnetization Refrigerator (ADR). The ADR cooler is explicitly needed to cool the NFI 2 array. The narrow field imager 1} Currently a 48 times 48 element array of superconducting tunnel junctions (STJ) is envisaged. Its operating temperature is in the range between 30 and 350 mK. Small, single Ta STJs (20-50 mum on a side) have shown 3.5 eV (FWHM) resolution at E = 525 eV and small arrays have been successfully demonstrated (6 times 6 pixels), or are currently tested (10 times 12 pixels). Alternatively, a prototype Distributed Read-Out Imaging Device (DROID), consisting of a linear superconducting Ta absorber of 20 times 100 mum2, including a 20 times 20 mum STJ for readout at either end, has shown a measured energy resolution of 2.4 eV (FWHM) at E = 500 eV. Simulations involving the diffusion properties as well as loss and tunnel rates have shown that the performance can be further improved by slight modifications in the geometry, and that the size of the DROIDS can be increased to 0.5-1.0 mm without loss in energy resolution. The relatively large areas and good energy resolution compared to single STJs make DROIDS good candidates for the

Hypersonic Flight Test Windows for Technology Development Testing

DTIC Science & Technology

2013-11-01

used. 2.1 Propulsion and Controls Test Window The technologies dealing with scramjet propulsion (inlets, fuel injection, etc.) and hypersonic ...AFRL-RQ-WP-TM-2013-0260 HYPERSONIC FLIGHT TEST WINDOWS FOR TECHNOLOGY DEVELOPMENT TESTING Barry M. Hellman Vehicle Technology Branch...DATES COVERED (From - To) November 2013 Final 01 November 2013 – 25 November 2013 4. TITLE AND SUBTITLE HYPERSONIC FLIGHT TEST WINDOWS FOR

Graphene Reinforced Glassy Carbon (GRGC) Beam Windows

DOE Office of Scientific and Technical Information (OSTI.GOV)

Renomeron, Lynda L.

Secondary particle beams require beam windows that isolate the target (usually in air) from the primary particle beam vacuum. Advanced beam window solutions are needed that can withstand anticipated increases in beam power and intensity that will result in higher thermal shock on the window and increased oxidative erosion rates on the air-side caused by increased temperatures. Carbon-based windows, in particular, glassy carbon windows are of interest to minimize interaction with the beam. The attractive properties of glassy carbon are: 1. Low atomic number 2. Low thermal expansion 3. High strength and low Young's modulus 4. Low gas permeability andmore » low outgassing for ultrahigh vacuum use The one liability of glassy carbon is its low thermal conductivity, nominally 5 W/mK, which will exacerbate temperature rise, oxidation, and thermal shock concerns as beam powers increase. TA&T proposes the development of graphene reinforced glassy carbon (GRGC) composites to increase the thermal conductivity and address this Achilles heel of glassy carbon. Graphene as a reinforcing phase has shown the capability to increase the thermal conductivity of the matrix material by up to two orders of magnitude. For beam windows this would substantially increase heat spreading away from the beam zone of the window and improve thermal shock resistance, and reduce maximum temperature and air-side oxidation of the window. Increased thermal conductivity would also improve the effectiveness of edge-cooling schemes to minimize temperature increase. In the Phase I effort, graphene oxide (GO) particles were dispersed into glassy carbon precursor at different content levels and cast into solid shapes. The goal was to determine the effect of graphene concentration on the mechanical properties (flexure strength), and thermal (thermal conductivity). The Phase I results indicated that addition of graphene did have a significant effect on thermal conductivity; however the microstructural

X-Windows Information Sharing Protocol Widget Class

NASA Technical Reports Server (NTRS)

Barry, Matthew R.

2006-01-01

The X-Windows Information Sharing Protocol (ISP) Widget Class ("Class") is used here in the object-oriented-programming sense of the word) was devised to simplify the task of implementing ISP graphical-user-interface (GUI) computer programs. ISP programming tasks require many method calls to identify, query, and interpret the connections and messages exchanged between a client and an ISP server. Most X-Windows GUI programs use widget sets or toolkits to facilitate management of complex objects. The widget standards facilitate construction of toolkits and application programs. The X-Windows Information Sharing Protocol (ISP) Widget Class encapsulates the client side of the ISP programming libraries within the framework of an X-Windows widget. Using the widget framework, X-Windows GUI programs can interact with ISP services in an abstract way and in the same manner as that of other graphical widgets, making it easier to write ISP GUI client programs. Wrapping ISP client services inside a widget framework enables a programmer to treat an ISP server interface as though it were a GUI. Moreover, an alternate subclass could implement another communication protocol in the same sort of widget.

"Broken windows" and the risk of gonorrhea.

PubMed Central

Cohen, D; Spear, S; Scribner, R; Kissinger, P; Mason, K; Wildgen, J

2000-01-01

OBJECTIVES: We examined the relationships between neighborhood conditions and gonorrhea. METHODS: We assessed 55 block groups by rating housing and street conditions. We mapped all cases of gonorrhea between 1994 and 1996 and calculated aggregated case rates by block group. We obtained public school inspection reports and assigned findings to the block groups served by the neighborhood schools. A "broken windows" index measured housing quality, abandoned cars, graffiti, trash, and public school deterioration. Using data from the 1990 census and 1995 updates, we determined the association between "broken windows," demographic characteristics, and gonorrhea rates. RESULTS: The broken windows index explained more of the variance in gonorrhea rates than did a poverty index measuring income, unemployment, and low education. In high-poverty neighborhoods, block groups with high broken windows scores had significantly higher gonorrhea rates than block groups with low broken windows scores (46.6 per 1000 vs 25.8 per 1000; P < .001). CONCLUSIONS: The robust association of deteriorated physical conditions of local neighborhoods with gonorrhea rates, independent of poverty, merits an intervention trial to test whether the environment has a causal role in influencing high-risk sexual behaviors. PMID:10667184

Narrow-Line Seyfert 1 Galaxies

NASA Technical Reports Server (NTRS)

Leighly, Karen M.

2000-01-01

The primary work during this year has been the analysis and interpretation of our HST spectra from two extreme Narrow-line Seyfert 1 galaxies (NLS1s) Infrared Astronomy Satellite (IRAS) 13224-3809 and 1H 0707-495. This work has been presented as an invited talk at the workshop entitled "Observational and theoretical progress in the Study of Narrow-line Seyfert 1 Galaxies" held in Bad Honnef, Germany December 8-11, as a contributed talk at the January 2000 AAS meeting in Atlanta, Georgia, and as a contributed talk at the workshop "Probing the Physics of Active Galactic Nuclei by Multiwavelength Monitoring" held at Goddard Space Flight Center June 20-22, 2000.

Oscillatory integration windows in neurons

PubMed Central

Gupta, Nitin; Singh, Swikriti Saran; Stopfer, Mark

2016-01-01

Oscillatory synchrony among neurons occurs in many species and brain areas, and has been proposed to help neural circuits process information. One hypothesis states that oscillatory input creates cyclic integration windows: specific times in each oscillatory cycle when postsynaptic neurons become especially responsive to inputs. With paired local field potential (LFP) and intracellular recordings and controlled stimulus manipulations we directly test this idea in the locust olfactory system. We find that inputs arriving in Kenyon cells (KCs) sum most effectively in a preferred window of the oscillation cycle. With a computational model, we show that the non-uniform structure of noise in the membrane potential helps mediate this process. Further experiments performed in vivo demonstrate that integration windows can form in the absence of inhibition and at a broad range of oscillation frequencies. Our results reveal how a fundamental coincidence-detection mechanism in a neural circuit functions to decode temporally organized spiking. PMID:27976720

Single-agent parallel window search

NASA Technical Reports Server (NTRS)

Powley, Curt; Korf, Richard E.

1991-01-01

Parallel window search is applied to single-agent problems by having different processes simultaneously perform iterations of Iterative-Deepening-A(asterisk) (IDA-asterisk) on the same problem but with different cost thresholds. This approach is limited by the time to perform the goal iteration. To overcome this disadvantage, the authors consider node ordering. They discuss how global node ordering by minimum h among nodes with equal f = g + h values can reduce the time complexity of serial IDA-asterisk by reducing the time to perform the iterations prior to the goal iteration. Finally, the two ideas of parallel window search and node ordering are combined to eliminate the weaknesses of each approach while retaining the strengths. The resulting approach, called simply parallel window search, can be used to find a near-optimal solution quickly, improve the solution until it is optimal, and then finally guarantee optimality, depending on the amount of time available.

Narrowing the wingless-2 mutation to a 227 kb candidate region on chicken chromosome 12

PubMed Central

Webb, A E; Youngworth, I A; Kaya, M; Gitter, C L; O’Hare, E A; May, B; Cheng, H H; Delany, M E

2018-01-01

ABSTRACT Wingless-2 (wg-2) is an autosomal recessive mutation in chicken that results in an embryonic lethal condition. Affected individuals exhibit a multisystem syndrome characterized by absent wings, truncated legs, and craniofacial, kidney, and feather malformations. Previously, work focused on phenotype description, establishing the autosomal recessive pattern of Mendelian inheritance and placing the mutation on an inbred genetic background to create the congenic line UCD Wingless-2.331. The research described in this paper employed the complementary tools of breeding, genetics, and genomics to map the chromosomal location of the mutation and successively narrow the size of the region for analysis of the causative element. Specifically, the wg-2 mutation was initially mapped to a 7 Mb region of chromosome 12 using an Illumina 3 K SNP array. Subsequent SNP genotyping and exon sequencing combined with analysis from improved genome assemblies narrowed the region of interest to a maximum size of 227 kb. Within this region, 3 validated and 3 predicted candidate genes are found, and these are described. The wg-2 mutation is a valuable resource to contribute to an improved understanding of the developmental pathways involved in chicken and avian limb development as well as serving as a model for human development, as the resulting syndrome shares features with human congenital disorders. PMID:29562287

Developmental changes in automatic rule-learning mechanisms across early childhood.

PubMed

Mueller, Jutta L; Friederici, Angela D; Männel, Claudia

2018-06-27

Infants' ability to learn complex linguistic regularities from early on has been revealed by electrophysiological studies indicating that 3-month-olds, but not adults, can automatically detect non-adjacent dependencies between syllables. While different ERP responses in adults and infants suggest that both linguistic rule learning and its link to basic auditory processing undergo developmental changes, systematic investigations of the developmental trajectories are scarce. In the present study, we assessed 2- and 4-year-olds' ERP indicators of pitch discrimination and linguistic rule learning in a syllable-based oddball design. To test for the relation between auditory discrimination and rule learning, ERP responses to pitch changes were used as predictor for potential linguistic rule-learning effects. Results revealed that 2-year-olds, but not 4-year-olds, showed ERP markers of rule learning. Although, 2-year-olds' rule learning was not dependent on differences in pitch perception, 4-year-old children demonstrated a dependency, such that those children who showed more pronounced responses to pitch changes still showed an effect of rule learning. These results narrow down the developmental decline of the ability for automatic linguistic rule learning to the age between 2 and 4 years, and, moreover, point towards a strong modification of this change by auditory processes. At an age when the ability of automatic linguistic rule learning phases out, rule learning can still be observed in children with enhanced auditory responses. The observed interrelations are plausible causes for age-of-acquisition effects and inter-individual differences in language learning. © 2018 John Wiley & Sons Ltd.

Window classification of brain CT images in biomedical articles.

PubMed

Xue, Zhiyun; Antani, Sameer; Long, L Rodney; Demner-Fushman, Dina; Thoma, George R

2012-01-01

Effective capability to search biomedical articles based on visual properties of article images may significantly augment information retrieval in the future. In this paper, we present a new method to classify the window setting types of brain CT images. Windowing is a technique frequently used in the evaluation of CT scans, and is used to enhance contrast for the particular tissue or abnormality type being evaluated. In particular, it provides radiologists with an enhanced view of certain types of cranial abnormalities, such as the skull lesions and bone dysplasia which are usually examined using the " bone window" setting and illustrated in biomedical articles using "bone window images". Due to the inherent large variations of images among articles, it is important that the proposed method is robust. Our algorithm attained 90% accuracy in classifying images as bone window or non-bone window in a 210 image data set.

Single level microelectronic device package with an integral window

DOEpatents

Peterson, Kenneth A.; Watson, Robert D.

2003-12-09

A package with an integral window for housing a microelectronic device. The integral window is bonded directly to the package without having a separate layer of adhesive material disposed in-between the window and the package. The device can be a semiconductor chip, CCD chip, CMOS chip, VCSEL chip, laser diode, MEMS device, or IMEMS device. The package can be formed of a multilayered LTCC or HTCC cofired ceramic material, with the integral window being simultaneously joined to the package during cofiring. The microelectronic device can be flip-chip interconnected so that the light-sensitive side is optically accessible through the window. A glob-top encapsulant or protective cover can be used to protect the microelectronic device and electrical interconnections. The result is a compact, low profile package having an integral window that is hermetically sealed to the package prior to mounting and interconnecting the microelectronic device.

2. Photocopied July 1971 from photostat Jordan Narrows Folder #1, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. Photocopied July 1971 from photostat Jordan Narrows Folder #1, Engineering Department, Utah Power and Light Co., Salt Lake City, Utah. JORDAN NARROWS STATION. PLAN AND SECTION. - Salt Lake City Water & Electrical Power Company, Jordan Narrows Hydroelectric Plant, Jordan River, Riverton, Salt Lake County, UT

SNS Proton Beam Window Disposal

NASA Astrophysics Data System (ADS)

Popova, Irina; Gallmeier, Franz X.; Trotter, Steven

2017-09-01

In order to support the disposal of the proton beam window assembly of the Spallation Neutron Source beamline to the target station, waste classification analyses are performed. The window has a limited life-time due to radiation-induced material damage. Analyses include calculation of the radionuclide inventory and shielding analyses for the transport package/container to ensure that the container is compliant with the transportation and waste management regulations. In order to automate this procedure and minimize manual work a script in Perl language was written.

Thermal and Optical Properties of Low-E Storm Windows and Panels

DOE Office of Scientific and Technical Information (OSTI.GOV)

Culp, Thomas D.; Widder, Sarah H.; Cort, Katherine A.

Installing low-emissivity (low-E) storm windows and panels over existing windows has been identified as a cost-effective new approach for improving the energy efficiency of existing buildings where window replacement is impractical or too expensive. As such, it is desirable to characterize the key energy performance properties of low-E storm windows and panels when installed over different types of existing primary windows. this paper presents the representative U-factors, solar heat gain coefficients (SGHCs) and visible transmittance properties of the combined assemblies of various storm windows and panel types installed over different primary windows.

An enhanced narrow-band imaging method for the microvessel detection

NASA Astrophysics Data System (ADS)

Yu, Feng; Song, Enmin; Liu, Hong; Wan, Youming; Zhu, Jun; Hung, Chih-Cheng

2018-02-01

A medical endoscope system combined with the narrow-band imaging (NBI), has been shown to be a superior diagnostic tool for early cancer detection. The NBI can reveal the morphologic changes of microvessels in the superficial cancer. In order to improve the conspicuousness of microvessel texture, we propose an enhanced NBI method to improve the conspicuousness of endoscopic images. To obtain the more conspicuous narrow-band images, we use the edge operator to extract the edge information of the narrow-band blue and green images, and give a weight to the extracted edges. Then, the weighted edges are fused with the narrow-band blue and green images. Finally, the displayed endoscopic images are reconstructed with the enhanced narrow-band images. In addition, we evaluate the performance of enhanced narrow-band images with different edge operators. Experimental results indicate that the Sobel and Canny operators achieve the best performance of all. Compared with traditional NBI method of Olympus company, our proposed method has more conspicuous texture of microvessel.

Bi-level microelectronic device package with an integral window

DOEpatents

Peterson, Kenneth A.; Watson, Robert D.

2004-01-06

A package with an integral window for housing a microelectronic device. The integral window is bonded directly to the package without having a separate layer of adhesive material disposed in-between the window and the package. The device can be a semiconductor chip, CCD chip, CMOS chip, VCSEL chip, laser diode, MEMS device, or IMEMS device. The multilayered package can be formed of a LTCC or HTCC cofired ceramic material, with the integral window being simultaneously joined to the package during LTCC or HTCC processing. The microelectronic device can be flip-chip bonded so that the light-sensitive side is optically accessible through the window. The package has at least two levels of circuits for making electrical interconnections to a pair of microelectronic devices. The result is a compact, low-profile package having an integral window that is hermetically sealed to the package prior to mounting and interconnecting the microelectronic device(s).

Asay window: A new spall diagnostic

NASA Astrophysics Data System (ADS)

McCluskey, Craig W.; Wilke, Mark D.; Anderson, William W.; Byers, Mark E.; Holtkamp, David B.; Rigg, Paulo A.; Furnish, Michael D.; Romero, Vincent T.

2006-11-01

By changing from the metallic foil of the Asay foil diagnostic, which can detect ejecta from a shocked surface, to a lithium fluoride (LiF) or polymethyl methacrylate (PMMA) window, it is possible to detect multiple spall layers and interlayer rubble. Past experiments to demonstrate this diagnostic have used high explosives (HEs) to shock metals to produce multiple spall layers. Because the exact characteristics of HE-induced spall layers cannot be predetermined, two issues exist in the quantitative interpretation of the data. First, to what level of fidelity is the Asay window method capable of providing quantitative information about spall layers, possibly separated by rubble, and second, contingent on the first, can an analytic technique be developed to convert the data to a meaningful description of spall from a given experiment? In this article, we address the first issue. A layered projectile fired from a gas gun was used to test the new diagnostic's accuracy and repeatability. We impacted a LiF or PMMA window viewed by a velocity interferometer system for any reflector (VISAR) probe with a projectile consisting of four thin stainless steel disks spaced apart 200μm with either vacuum or polyethylene. The window/surface interface velocity measured with a VISAR probe was compared with calculations. The good agreement observed between the adjusted calculation and the measured data indicates that, in principle and given enough prior information, it is possible to use the Asay window data to model a density distribution from spalled material with simple hydrodynamic models and only simple adjustments to nominal predictions.

Lower HVAC Costs | Efficient Windows Collaborative

Science.gov Websites

system. Smaller HVAC systems cost less and as such can offset some of the cost of the efficient windows dehumidification. First cost savings - Smaller HVAC units cost less. If, for example, down-sizing the HVAC system by half a ton saves $275, the cost premium of energy-efficient windows does not present as big an up

Associations between narrow angle and adult anthropometry: the Liwan Eye Study.

PubMed

Jiang, Yuzhen; He, Mingguang; Friedman, David S; Khawaja, Anthony P; Lee, Pak Sang; Nolan, Winifred P; Yin, Qiuxia; Foster, Paul J

2014-06-01

To assess the associations between narrow angle and adult anthropometry. Chinese adults aged 50 years and older were recruited from a population-based survey in the Liwan District of Guangzhou, China. Narrow angle was defined as the posterior trabecular meshwork not visible under static gonioscopy in at least three quadrants (i.e. a circumference of at least 270°). Logistic regression models were used to examine the associations between narrow angle and anthropomorphic measures (height, weight and body mass index, BMI). Among the 912 participants, lower weight, shorter height, and lower BMI were significantly associated with narrower angle width (tests for trend: mean angle width in degrees vs weight p < 0.001; vs height p < 0.001; vs BMI p = 0.012). In univariate analyses, shorter height, lower weight and lower BMI were all significantly associated with greater odds of narrow angle. The crude association between height and narrow angle was largely attributable to a stronger association with age and sex. Lower BMI and weight remained significantly associated with narrow angle after adjustment for height, age, sex, axial ocular biometric measures and education. In analyses stratified by sex, the association between BMI and narrow angle was only observed in women. Lower BMI and weight were associated with significantly greater odds of narrow angle after adjusting for age, education, axial ocular biometric measures and height. The odds of narrow angle increased 7% per 1 unit decrease in BMI. This association was most evident in women.

Rigorous Numerical Study of Low-Period Windows for the Quadratic Map

NASA Astrophysics Data System (ADS)

Galias, Zbigniew

An efficient method to find all low-period windows for the quadratic map is proposed. The method is used to obtain very accurate rigorous bounds of positions of all periodic windows with periods p ≤ 32. The contribution of period-doubling windows on the total width of periodic windows is discussed. Properties of periodic windows are studied numerically.

Microelectronic device package with an integral window

DOEpatents

Peterson, Kenneth A.; Watson, Robert D.

2002-01-01

An apparatus for packaging of microelectronic devices, including an integral window. The microelectronic device can be a semiconductor chip, a CCD chip, a CMOS chip, a VCSEL chip, a laser diode, a MEMS device, or a IMEMS device. The package can include a cofired ceramic frame or body. The package can have an internal stepped structure made of one or more plates, with apertures, which are patterned with metallized conductive circuit traces. The microelectronic device can be flip-chip bonded on the plate to these traces, and oriented so that the light-sensitive side is optically accessible through the window. A cover lid can be attached to the opposite side of the package. The result is a compact, low-profile package, having an integral window that can be hermetically-sealed. The package body can be formed by low-temperature cofired ceramic (LTCC) or high-temperature cofired ceramic (HTCC) multilayer processes with the window being simultaneously joined (e.g. cofired) to the package body during LTCC or HTCC processing. Multiple chips can be located within a single package. The cover lid can include a window. The apparatus is particularly suited for packaging of MEMS devices, since the number of handling steps is greatly reduced, thereby reducing the potential for contamination.

Rugged sensor window materials for harsh environments

NASA Astrophysics Data System (ADS)

Bayya, Shyam; Villalobos, Guillermo; Kim, Woohong; Sanghera, Jasbinger; Hunt, Michael; Aggarwal, Ishwar D.

2014-09-01

There are several military or commercial systems operating in very harsh environments that require rugged windows. On some of these systems, windows become the single point of failure. These applications include sensor or imaging systems, high-energy laser weapons systems, submarine photonic masts, IR countermeasures and missiles. Based on the sea or land or air based platforms the window or dome on these systems must withstand wave slap, underwater or ground based explosions, or survive flight through heavy rain and sand storms while maintaining good optical transmission in the desired wavelength range. Some of these applications still use softer ZnS or fused silica windows because of lack of availability of rugged materials in shapes or sizes required. Sapphire, ALON and spinel are very rugged materials with significantly higher strengths compared to ZnS and fused silica. There have been recent developments in spinel, ALON and sapphire materials to fabricate in large sizes and conformal shapes. We have been developing spinel ceramics for several of these applications. We are also developing β-SiC as a transparent window material as it has higher hardness, strength, and toughness than sapphire, ALON and spinel. This paper gives a summary of our recent findings.

Overview of Fabrication Techniques and Lessons Learned with Accelerator Vacuum Windows

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ader, C. R.; McGee, M. W.; Nobrega, L. E.

Vacuum thin windows have been used in Fermilab's accelerators for decades and typically have been overlooked in terms of their criticality and fragility. Vacuum windows allow beam to pass through while creating a boundary between vacuum and air or high vacuum and low vacuum areas. The design of vacuum windows, including Titanium and Beryllium windows, will be discussed as well as fabrication, testing, and operational concerns. Failure of windows will be reviewed as well as safety approaches to mitigating failures and extending the lifetimes of vacuum windows. Various methods of calculating the strengths of vacuum windows will be explored, includingmore » FEA.« less

Hot Wax Sweeps Debris From Narrow Passages

NASA Technical Reports Server (NTRS)

Ricklefs, Steven K.

1990-01-01

Safe and effective technique for removal of debris and contaminants from narrow passages involves entrainment of undesired material in thermoplastic casting material. Semisolid wax slightly below melting temperature pushed along passage by pressurized nitrogen to remove debris. Devised to clean out fuel passages in main combustion chamber of Space Shuttle main engine. Also applied to narrow, intricate passages in internal-combustion-engine blocks, carburetors, injection molds, and other complicated parts.

THERM 5 / WINDOW 5 NFRC simulation manual

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mitchell, Robin; Kohler, Christian; Arasteh, Dariush

This document, the ''THERM 5/WINDOW 5 NFRC Simulation Manual', discusses how to use the THERM and WINDOW programs to model products for NFRC certified simulations and assumes that the user is already familiar with those programs. In order to learn how to use these programs, it is necessary to become familiar with the material in both the ''THERM User's Manual'' and the ''WINDOW User's Manual''. In general, this manual references the User's Manuals rather than repeating the information. If there is a conflict between either of the User Manual and this ''THERM 5/''WINDOW 5 NFRC Simulation Manual'', the ''THERM 5/WINDOWmore » 5 NFRC Simulation Manual'' takes precedence. In addition, if this manual is in conflict with any NFRC standards, the standards take precedence. For example, if samples in this manual do not follow the current taping and testing NFRC standards, the standards not the samples in this manual, take precedence.« less

Developmental Screening

MedlinePlus

Learn More about Your Child’s Development: Developmental Monitoring and Screening Taking a first step, waving “bye-bye,” and pointing to something interesting are all developmental milestones, ...

Due-Window Assignment Scheduling with Variable Job Processing Times

PubMed Central

Wu, Yu-Bin

2015-01-01

We consider a common due-window assignment scheduling problem jobs with variable job processing times on a single machine, where the processing time of a job is a function of its position in a sequence (i.e., learning effect) or its starting time (i.e., deteriorating effect). The problem is to determine the optimal due-windows, and the processing sequence simultaneously to minimize a cost function includes earliness, tardiness, the window location, window size, and weighted number of tardy jobs. We prove that the problem can be solved in polynomial time. PMID:25918745

Fracture strength and probability of survival of narrow and extra-narrow dental implants after fatigue testing: In vitro and in silico analysis.

PubMed

Bordin, Dimorvan; Bergamo, Edmara T P; Fardin, Vinicius P; Coelho, Paulo G; Bonfante, Estevam A

2017-07-01

To assess the probability of survival (reliability) and failure modes of narrow implants with different diameters. For fatigue testing, 42 implants with the same macrogeometry and internal conical connection were divided, according to diameter, as follows: narrow (Ø3.3×10mm) and extra-narrow (Ø2.9×10mm) (21 per group). Identical abutments were torqued to the implants and standardized maxillary incisor crowns were cemented and subjected to step-stress accelerated life testing (SSALT) in water. The use-level probability Weibull curves, and reliability for a mission of 50,000 and 100,000 cycles at 50N, 100, 150 and 180N were calculated. For the finite element analysis (FEA), two virtual models, simulating the samples tested in fatigue, were constructed. Loading at 50N and 100N were applied 30° off-axis at the crown. The von-Mises stress was calculated for implant and abutment. The beta (β) values were: 0.67 for narrow and 1.32 for extra-narrow implants, indicating that failure rates did not increase with fatigue in the former, but more likely were associated with damage accumulation and wear-out failures in the latter. Both groups showed high reliability (up to 97.5%) at 50 and 100N. A decreased reliability was observed for both groups at 150 and 180N (ranging from 0 to 82.3%), but no significant difference was observed between groups. Failure predominantly involved abutment fracture for both groups. FEA at 50N-load, Ø3.3mm showed higher von-Mises stress for abutment (7.75%) and implant (2%) when compared to the Ø2.9mm. There was no significant difference between narrow and extra-narrow implants regarding probability of survival. The failure mode was similar for both groups, restricted to abutment fracture. Copyright © 2017 Elsevier Ltd. All rights reserved.

I. DEVELOPMENTAL METHODOLOGY AS A CENTRAL SUBDISCIPLINE OF DEVELOPMENTAL SCIENCE.

PubMed

Card, Noel A

2017-06-01

This first chapter introduces the main goals of the monograph and previews the remaining chapters. The goals of this monograph are to provide summaries of our current understanding of advanced developmental methodologies, provide information that can advance our understanding of human development, identify shortcomings in our understanding of developmental methodology, and serve as a flagpost for organizing developmental methodology as a subdiscipline within the broader field of developmental science. The remaining chapters in this monograph address issues in design (sampling and big data), longitudinal data analysis, and issues of replication and research accumulation. The final chapter describes the history of developmental methodology, considers how the previous chapters in this monograph fit within this subdiscipline, and offers recommendations for further advancement. © 2017 The Society for Research in Child Development, Inc.

26 CFR 31.3406(b)(2)-3 - Window transactions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 26 Internal Revenue 15 2010-04-01 2010-04-01 false Window transactions. 31.3406(b)(2)-3 Section 31... SOURCE Collection of Income Tax at Source § 31.3406(b)(2)-3 Window transactions. (a) Requirement to backup withhold. Withholding under section 3406 applies to a window transaction (as defined in paragraph...

Associations between Narrow Angle and Adult Anthropometry: The Liwan Eye Study

PubMed Central

Jiang, Yuzhen; He, Mingguang; Friedman, David S.; Khawaja, Anthony P.; Lee, Pak Sang; Nolan, Winifred P.; Yin, Qiuxia; Foster, Paul J.

2015-01-01

Purpose To assess the associations between narrow angle and adult anthropometry. Methods Chinese adults aged 50 years and older were recruited from a population-based survey in the Liwan District of Guangzhou, China. Narrow angle was defined as the posterior trabecular meshwork not visible under static gonioscopy in at least three quadrants (i.e. a circumference of at least 270°). Logistic regression models were used to examine the associations between narrow angle and anthropomorphic measures (height, weight and body mass index, BMI). Results Among the 912 participants, lower weight, shorter height, and lower BMI were significantly associated with narrower angle width (tests for trend: mean angle width in degrees vs weight p<0.001; vs height p<0.001; vs BMI p = 0.012). In univariate analyses, shorter height, lower weight and lower BMI were all significantly associated with greater odds of narrow angle. The crude association between height and narrow angle was largely attributable to a stronger association with age and sex. Lower BMI and weight remained significantly associated with narrow angle after adjustment for height, age, sex, axial ocular biometric measures and education. In analyses stratified by sex, the association between BMI and narrow angle was only observed in women. Conclusion Lower BMI and weight were associated with significantly greater odds of narrow angle after adjusting for age, education, axial ocular biometric measures and height. The odds of narrow angle increased 7% per 1 unit decrease in BMI. This association was most evident in women. PMID:24707840

Defining the flexibility window in ordered aluminosilicate zeolites

PubMed Central

Wells, Stephen A.; Leung, Ka Ming; Edwards, Peter P.; Tucker, Matt G.

2017-01-01

The flexibility window in zeolites was originally identified using geometric simulation as a hypothetical property of SiO2 systems. The existence of the flexibility window in hypothetical structures may help us to identify those we might be able to synthesize in the future. We have previously found that the flexibility window in silicates is connected to phase transitions under pressure, structure amorphization and other physical behaviours and phenomena. We here extend the concept to ordered aluminosilicate systems using softer ‘bar’ constraints that permit additional flexibility around aluminium centres. Our experimental investigation of pressure-induced amorphization in sodalites is consistent with the results of our modelling. The softer constraints allow us to identify a flexibility window in the anomalous case of goosecreekite. PMID:28989777

Noguchi at JPM window during Expedition 22

NASA Image and Video Library

2010-03-12

ISS022-E-091518 (12 March 2010) --- Japan Aerospace Exploration Agency (JAXA) astronaut Soichi Noguchi, Expedition 22 flight engineer, looks through a window in the Kibo laboratory of the International Space Station. The Japanese robotic Small Fine Arm (SFA), also known as ?Ko-bot?, is visible through the window.

Windows in direct dissociative recombination cross sections

NASA Technical Reports Server (NTRS)

Guberman, Steven L.

1986-01-01

Model potential curves are used to show that large windows are present in direct dissociative-recombination cross sections from excited molecular-ion vibrational levels. The windows are due to the overlap of vibrational wave functions of the repulsive neutral states with the nodes of the ion vibrational wave function.

Design and comparison of laser windows for high-power lasers

NASA Astrophysics Data System (ADS)

Niu, Yanxiong; Liu, Wenwen; Liu, Haixia; Wang, Caili; Niu, Haisha; Man, Da

2014-11-01

High-power laser systems are getting more and more widely used in industry and military affairs. It is necessary to develop a high-power laser system which can operate over long periods of time without appreciable degradation in performance. When a high-energy laser beam transmits through a laser window, it is possible that the permanent damage is caused to the window because of the energy absorption by window materials. So, when we design a high-power laser system, a suitable laser window material must be selected and the laser damage threshold of the window must be known. In this paper, a thermal analysis model of high-power laser window is established, and the relationship between the laser intensity and the thermal-stress field distribution is studied by deducing the formulas through utilizing the integral-transform method. The influence of window radius, thickness and laser intensity on the temperature and stress field distributions is analyzed. Then, the performance of K9 glass and the fused silica glass is compared, and the laser-induced damage mechanism is analyzed. Finally, the damage thresholds of laser windows are calculated. The results show that compared with K9 glass, the fused silica glass has a higher damage threshold due to its good thermodynamic properties. The presented theoretical analysis and simulation results are helpful for the design and selection of high-power laser windows.

Adaptive Window Zero-Crossing-Based Instantaneous Frequency Estimation

NASA Astrophysics Data System (ADS)

Sekhar, S. Chandra; Sreenivas, TV

2004-12-01

We address the problem of estimating instantaneous frequency (IF) of a real-valued constant amplitude time-varying sinusoid. Estimation of polynomial IF is formulated using the zero-crossings of the signal. We propose an algorithm to estimate nonpolynomial IF by local approximation using a low-order polynomial, over a short segment of the signal. This involves the choice of window length to minimize the mean square error (MSE). The optimal window length found by directly minimizing the MSE is a function of the higher-order derivatives of the IF which are not available a priori. However, an optimum solution is formulated using an adaptive window technique based on the concept of intersection of confidence intervals. The adaptive algorithm enables minimum MSE-IF (MMSE-IF) estimation without requiring a priori information about the IF. Simulation results show that the adaptive window zero-crossing-based IF estimation method is superior to fixed window methods and is also better than adaptive spectrogram and adaptive Wigner-Ville distribution (WVD)-based IF estimators for different signal-to-noise ratio (SNR).

Window decompression in laser-heated MagLIF targets

NASA Astrophysics Data System (ADS)

Woodbury, Daniel; Peterson, Kyle; Sefkow, Adam

2015-11-01

The Magnetized Liner Inertial Fusion (MagLIF) concept requires pre-magnetized fuel to be pre-heated with a laser before undergoing compression by a thick solid liner. Recent experiments and simulations suggest that yield has been limited to date by poor laser preheat and laser-induced mix in the fuel region. In order to assess laser energy transmission through the pressure-holding window, as well as resultant mix, we modeled window disassembly under different conditions using 1D and 2D simulations in both Helios and HYDRA. We present results tracking energy absorption, time needed for decompression, risk of laser-plasma interaction (LPI) that may scatter laser light, and potential for mix from various window thicknesses, laser spot sizes and gas fill densities. These results indicate that using thinner windows (0.5-1 μm windows) and relatively large laser spot radii (600 μm and above) can avoid deleterious effects and improve coupling with the fuel. Sandia is a multiprogram laboratory operated by Sandia Corporation, a Lockheed Martin Company, for the National Nuclear Security Administration under DE-AC04- 94AL85000.

Ultra-thin narrow-band, complementary narrow-band, and dual-band metamaterial absorbers for applications in the THz regime

NASA Astrophysics Data System (ADS)

Astorino, Maria Denise; Frezza, Fabrizio; Tedeschi, Nicola

2017-02-01

In this paper, ultra-thin narrow-band, complementary narrow-band, and dual-band metamaterial absorbers (MMAs), exploiting the same electric ring resonator configuration, are investigated at normal and oblique incidence for both transverse electric (TE) and transverse magnetic (TM) polarizations, and with different physical properties in the THz regime. In the analysis of the ultra-thin narrow-band MMA, the limit of applicability of the transmission line model has been overcome with the introduction of a capacitance which considers the z component of the electric field. These absorbing structures have shown a wide angular response and a polarization-insensitive behavior due to the introduction of a conducting ground plane and to the four-fold rotational symmetry of the resonant elements around the propagation axis. We have adopted a retrieval procedure to extract the effective electromagnetic parameters of the proposed MMAs and we have compared the simulated and analytical results through the interference theory.

Narrow-band generation in random distributed feedback fiber laser.

PubMed

Sugavanam, Srikanth; Tarasov, Nikita; Shu, Xuewen; Churkin, Dmitry V

2013-07-15

Narrow-band emission of spectral width down to ~0.05 nm line-width is achieved in the random distributed feedback fiber laser employing narrow-band fiber Bragg grating or fiber Fabry-Perot interferometer filters. The observed line-width is ~10 times less than line-width of other demonstrated up to date random distributed feedback fiber lasers. The random DFB laser with Fabry-Perot interferometer filter provides simultaneously multi-wavelength and narrow-band (within each line) generation with possibility of further wavelength tuning.

Mouse Driven Window Graphics for Network Teaching.

ERIC Educational Resources Information Center

Makinson, G. J.; And Others

Computer enhanced teaching of computational mathematics on a network system driving graphics terminals is being redeveloped for a mouse-driven, high resolution, windowed environment of a UNIX work station. Preservation of the features of networked access by heterogeneous terminals is provided by the use of the X Window environment. A dmonstrator…

Consequences of narrow cyclotron emission from Hercules X-1

NASA Technical Reports Server (NTRS)

Weaver, R. P.

1978-01-01

The implications of the recent observations of a narrow cyclotron line in the hard X-ray spectrum of Hercules X-1 are studied. A Monte Carlo code is used to simulate the X-ray transfer of an intrinsically narrow feature at approximately 56 keV through an opaque, cold magnetospheric shell. The results of this study indicate that if a narrow line can be emitted by the source region, then only about 10% of the photons remain in a narrow feature after scattering through the shell. The remaining photons are scattered into a broad feature (FWHM approximately 30 keV) that peaks near 20 keV. Thus, these calculations indicate that the intrinsic source luminosity of the cyclotron line is at least an order of magnitude greater than the observed luminosity.

Determination of electron energy, spectral width, and beam divergence at the exit window for clinical megavoltage x-ray beams.

PubMed

Sawkey, D L; Faddegon, B A

2009-03-01

Monte Carlo simulations of x-ray beams typically take parameters of the electron beam in the accelerating waveguide to be free parameters. In this paper, a methodology is proposed and implemented to determine the energy, spectral width, and beam divergence of the electron source. All treatment head components were removed from the beam path, leaving only the exit window. With the x-ray target and flattener out of the beam, uncertainties in physical characteristics and relative position of the target and flattening filter, and in spot size, did not contribute to uncertainty in the energy. Beam current was lowered to reduce recombination effects. The measured dose distributions were compared with Monte Carlo simulation of the electron beam through the treatment head to extract the electron source characteristics. For the nominal 6 and 18 MV x-ray beams, the energies were 6.51 +/- 0.15 and 13.9 +/- 0.2 MeV, respectively, with the uncertainties resulting from uncertainties in the detector position in the measurement and in the stopping power in the simulations. Gaussian spectral distributions were used, with full widths at half maximum ranging from 20 +/- 4% at 6 MV to 13 +/- 4% at 18 MV required to match the fall-off portion of the percent-depth ionization curve. Profiles at the depth of maximum dose from simulations that used the manufacturer-specified exit window geometry and no beam divergence were 2-3 cm narrower than measured profiles. Two simulation configurations yielding the measured profile width were the manufacturer-specified exit window thickness with electron source divergences of 3.3 degrees at 6 MV and 1.8 degrees at 18 MV and an exit window 40% thicker than the manufacturer's specification with no beam divergence. With the x-ray target in place (and no flattener), comparison of measured to simulated profiles sets upper limits on the electron source divergences of 0.2 degrees at 6 MV and 0.1 degrees at 18 MV. A method of determining source

30 CFR 18.66 - Tests of windows and lenses.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Tests of windows and lenses. 18.66 Section 18... Tests § 18.66 Tests of windows and lenses. (a) Impact tests. A 4-pound cylindrical weight with a 1-inch-diameter hemispherical striking surface shall be dropped (free fall) to strike the window or lens in its...

Error-Based Design Space Windowing

NASA Technical Reports Server (NTRS)

Papila, Melih; Papila, Nilay U.; Shyy, Wei; Haftka, Raphael T.; Fitz-Coy, Norman

2002-01-01

Windowing of design space is considered in order to reduce the bias errors due to low-order polynomial response surfaces (RS). Standard design space windowing (DSW) uses a region of interest by setting a requirement on response level and checks it by a global RS predictions over the design space. This approach, however, is vulnerable since RS modeling errors may lead to the wrong region to zoom on. The approach is modified by introducing an eigenvalue error measure based on point-to-point mean squared error criterion. Two examples are presented to demonstrate the benefit of the error-based DSW.

Communication-based assessment of developmental age for young children with developmental disabilities.

PubMed

DeVeney, Shari L; Hoffman, Lesa; Cress, Cynthia J

2012-06-01

In this study, the authors compared a multiple-domain strategy for assessing developmental age of young children with developmental disabilities who were at risk for long-term reliance on augmentative and alternative communication (AAC) with a communication-based strategy composed of receptive language and communication indices that may be less affected by physically challenging tasks than traditional developmental age scores. Participants were 42 children (age 9-27 months) with developmental disabilities and who were at risk for long-term reliance on AAC. Children were assessed longitudinally in their homes at 3 occasions over 18 months using multiple-domain and communication-based measures. Confirmatory factor analysis examined dimensionality across the measures, and age-equivalence scores under each strategy were compared, where possible. The communication-based latent factor of developmental age demonstrated good reliability and was almost perfectly correlated with the multiple-domain latent factor. However, the mean age-equivalence score of the communication-based assessment significantly exceeded that of the multiple-domain assessment by 5.3 months across ages. Clinicians working with young children with developmental disabilities should consider a communication-based approach as an alternative developmental age assessment strategy for characterizing children's capabilities, identifying challenges, and developing interventions. A communication-based developmental age estimation is sufficiently reliable and may result in more valid inferences about developmental age for children whose developmental or cognitive age scores may otherwise be limited by their physical capabilities.

Multilayered Microelectronic Device Package With An Integral Window

DOEpatents

Peterson, Kenneth A.; Watson, Robert D.

2004-10-26

A microelectronic package with an integral window mounted in a recessed lip for housing a microelectronic device. The device can be a semiconductor chip, a CCD chip, a CMOS chip, a VCSEL chip, a laser diode, a MEMS device, or a IMEMS device. The package can be formed of a low temperature co-fired ceramic (LTCC) or high temperature cofired ceramic (HTCC) multilayered material, with the integral window being simultaneously joined (e.g. co-fired) to the package body during LTCC or HTCC processing. The microelectronic device can be flip-chip bonded and oriented so that a light-sensitive side is optically accessible through the window. The result is a compact, low profile package, having an integral window mounted in a recessed lip, that can be hermetically sealed.

Study of noise transmission through double wall aircraft windows

NASA Technical Reports Server (NTRS)

Vaicaitis, R.

1983-01-01

Analytical and experimental procedures were used to predict the noise transmitted through double wall windows into the cabin of a twin-engine G/A aircraft. The analytical model was applied to optimize cabin noise through parametric variation of the structural and acoustic parameters. The parametric study includes mass addition, increase in plexiglass thickness, decrease in window size, increase in window cavity depth, depressurization of the space between the two window plates, replacement of the air cavity with a transparent viscoelastic material, change in stiffness of the plexiglass material, and different absorptive materials for the interior walls of the cabin. It was found that increasing the exterior plexiglass thickness and/or decreasing the total window size could achieve the proper amount of noise reduction for this aircraft. The total added weight to the aircraft is then about 25 lbs.

A large, switchable optical clearing skull window for cerebrovascular imaging

PubMed Central

Zhang, Chao; Feng, Wei; Zhao, Yanjie; Yu, Tingting; Li, Pengcheng; Xu, Tonghui; Luo, Qingming; Zhu, Dan

2018-01-01

Rationale: Intravital optical imaging is a significant method for investigating cerebrovascular structure and function. However, its imaging contrast and depth are limited by the turbid skull. Tissue optical clearing has a great potential for solving this problem. Our goal was to develop a transparent skull window, without performing a craniotomy, for use in assessing cerebrovascular structure and function. Methods: Skull optical clearing agents were topically applied to the skulls of mice to create a transparent window within 15 min. The clearing efficacy, repeatability, and safety of the skull window were then investigated. Results: Imaging through the optical clearing skull window enhanced both the contrast and the depth of intravital imaging. The skull window could be used on 2-8-month-old mice and could be expanded from regional to bi-hemispheric. In addition, the window could be repeatedly established without inducing observable inflammation and metabolic toxicity. Conclusion: We successfully developed an easy-to-handle, large, switchable, and safe optical clearing skull window. Combined with various optical imaging techniques, cerebrovascular structure and function can be observed through this optical clearing skull window. Thus, it has the potential for use in basic research on the physiopathologic processes of cortical vessels. PMID:29774069

The Anti-Methicillin-Resistant Staphylococcus aureus Quinolone WCK 771 Has Potent Activity against Sequentially Selected Mutants, Has a Narrow Mutant Selection Window against Quinolone-Resistant Staphylococcus aureus, and Preferentially Targets DNA Gyrase▿ †

PubMed Central

Bhagwat, Sachin S.; Mundkur, Lakshmi A.; Gupte, Shrikant V.; Patel, Mahesh V.; Khorakiwala, Habil F.

2006-01-01

WCK 771 is a broad-spectrum fluoroquinolone with enhanced activity against quinolone-resistant staphylococci. To understand the impact of the target-level interactions of WCK 771 on its antistaphylococcal pharmacodynamic properties, we determined the MICs for genetically defined mutants and studied the mutant prevention concentrations (MPCs), the frequency of mutation, and the cidality against the wild type and double mutants. There was a twofold increase in the MICs of WCK 771 for single gyrA mutants, indicating that DNA gyrase is its primary target. All first- and second-step mutants selected by WCK 771 revealed gyrA and grlA mutations, respectively. The MICs of WCK 771 and clinafloxacin were found to be superior to those of other quinolones against strains with double and triple mutations. WCK 771 was also cidal for high-density double mutants at low concentrations. WCK 771 and clinafloxacin showed narrow mutant selection windows compared to those of the other quinolones. Against a panel of 50 high-level quinolone-resistant clinical isolates of staphylococci (ciprofloxacin MIC ≥ 16 μg/ml), the WCK 771 MPCs were ≤2 μg/ml for 68% of the strains and ≤4 μg/ml for 28% of the strains. Our results demonstrate that gyrA is the primary target of WCK 771 and that it has pharmacodynamic properties remarkably different from those of quinolones with dual targets (garenoxacin and moxifloxacin) and topoisomerase IV-specific quinolones (trovafloxacin). WCK 771 displayed an activity profile comparable to that of clinafloxacin, a dual-acting quinolone with a high affinity to DNA gyrase. Overall, the findings signify the key role of DNA gyrase in determining the optimal antistaphylococcal features of quinolones. PMID:16940059

Exploiting the extraordinary genetic polymorphism of ciona for developmental genetics with whole genome sequencing.

PubMed

Abdul-Wajid, Sarah; Veeman, Michael T; Chiba, Shota; Turner, Thomas L; Smith, William C

2014-05-01

Studies in tunicates such as Ciona have revealed new insights into the evolutionary origins of chordate development. Ciona populations are characterized by high levels of natural genetic variation, between 1 and 5%. This variation has provided abundant material for forward genetic studies. In the current study, we make use of deep sequencing and homozygosity mapping to map spontaneous mutations in outbred populations. With this method we have mapped two spontaneous developmental mutants. In Ciona intestinalis we mapped a short-tail mutation with strong phenotypic similarity to a previously identified mutant in the related species Ciona savignyi. Our bioinformatic approach mapped the mutation to a narrow interval containing a single mutated gene, α-laminin3,4,5, which is the gene previously implicated in C. savignyi. In addition, we mapped a novel genetic mutation disrupting neural tube closure in C. savignyi to a T-type Ca(2+) channel gene. The high efficiency and unprecedented mapping resolution of our study is a powerful advantage for developmental genetics in Ciona, and may find application in other outbred species.

A prospective randomized controlled trial of the two-window technique without membrane versus the solo-window technique with membrane over the osteotomy window for maxillary sinus augmentation.

PubMed

Yu, Huajie; He, Danqing; Qiu, Lixin

2017-12-01

Maturation of the grafted volume after lateral sinus elevation is crucial for the long-term survival of dental implants. To compare endo-sinus histomorphometric bone formation between the solo- and two-window maxillary sinus augmentation techniques with or without membrane coverage for the rehabilitation of multiple missing posterior teeth. Patients with severely atrophic posterior maxillae were randomized to receive lateral sinus floor elevation via the solo-window technique with membrane coverage (Control Group) or the two-window technique without coverage (Test Group). Six months after surgery, bone core specimens harvested from the lateral aspect were histomorphometrically analyzed. Ten patients in each group underwent 21 maxillary sinus augmentations. Histomorphometric analysis revealed mean newly formed bone values of 26.08 ± 16.23% and 27.14 ± 18.11%, mean connective tissue values of 59.34 ± 12.42% and 50.03 ± 17.13%, and mean residual graft material values of 14.6 ± 14.56% and 22.78 ± 10.83% in the Test and Control Groups, respectively, with no significant differences. The two-window technique obtained comparative maturation of the grafted volume even without membrane coverage, and is a viable alternative for the rehabilitation of severely atrophic posterior maxillae with multiple missing posterior teeth. © 2017 Wiley Periodicals, Inc.

Design, Construction, Demonstration and Delivery of an Automated Narrow Gap Welding System.

DTIC Science & Technology

1982-06-29

DESIGN, CONSTRUCTION, DEMONSTRATION AND DELIVERY OF WE DA4I &NARROW GAP CONTRACT NO. NOOGOO-81-C-E923 TO DAVID TAYLOR NAVAL RESEARCH AND DEVELOPMENT...the automated * Narrow Gap welding process, is the narrow (3/8 - inch), square-butt joint *design. This narrow joint greatly reduces the volume of weld...AD-i45 495 DESIGN CONSTRUCTION DEMONSTRATION AiND DELIVERY OF RN 1/j AUrOMATED NARROW GAP WELDING SYSTEMI() CRC AUTOMATIC WELDING CO HOUSTON TX 29

Bayesian Face Recognition and Perceptual Narrowing in Face-Space

PubMed Central

Balas, Benjamin

2012-01-01

During the first year of life, infants’ face recognition abilities are subject to “perceptual narrowing,” the end result of which is that observers lose the ability to distinguish previously discriminable faces (e.g. other-race faces) from one another. Perceptual narrowing has been reported for faces of different species and different races, in developing humans and primates. Though the phenomenon is highly robust and replicable, there have been few efforts to model the emergence of perceptual narrowing as a function of the accumulation of experience with faces during infancy. The goal of the current study is to examine how perceptual narrowing might manifest as statistical estimation in “face space,” a geometric framework for describing face recognition that has been successfully applied to adult face perception. Here, I use a computer vision algorithm for Bayesian face recognition to study how the acquisition of experience in face space and the presence of race categories affect performance for own and other-race faces. Perceptual narrowing follows from the establishment of distinct race categories, suggesting that the acquisition of category boundaries for race is a key computational mechanism in developing face expertise. PMID:22709406

SOT: A rapid prototype using TAE windows

NASA Technical Reports Server (NTRS)

Stephens, Mark; Eike, David; Harris, Elfrieda; Miller, Dana

1986-01-01

The development of the window interface extension feature of the Transportable Applications Executive (TAE) is discussed. This feature is being used to prototype a space station payload interface in order to demonstrate and assess the benefits of using windows on a bit mapped display and also to convey the concept of telescience, the control and operation of space station payloads from remote sites. The prototype version of the TAE with windows operates on a DEC VAXstation 100. This workstation has a high resolution 19 inch bit mapped display, a keyboard and a three-button mouse. The VAXstation 100 is not a stand-alone workstation, but is controlled by software executing on a VAX/8600. A short scenario was developed utilizing the Solar Optical Telescope (SOT) as an example payload. In the scenario the end-user station includes the VAXstation 100 plus an image analysis terminal used to display the CCD images. The layout and use of the prototype elements, i.e., the root menu, payload status window, and target acquisition menu is described.

WinSCP for Windows File Transfers | High-Performance Computing | NREL

Science.gov Websites

WinSCP for Windows File Transfers WinSCP for Windows File Transfers WinSCP for can used to securely transfer files between your local computer running Microsoft Windows and a remote computer running Linux

DETAIL VIEW, WEST VENETIAN WINDOW IN SOUTH WALL. (NOTE THE ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

DETAIL VIEW, WEST VENETIAN WINDOW IN SOUTH WALL. (NOTE THE IRON BARS ON THE CELLAR WINDOW BELOW. THIS WINDOW LETS ONTO WHAT WAS LIKELY THE ESTATE OFFICE DURING THE HAMILTONIAN RESIDENCY - The Woodlands, 4000 Woodlands Avenue, Philadelphia, Philadelphia County, PA

Developmental Toxicity

EPA Science Inventory

This chapter provides an overview the developmental toxicity resulting from exposure to perfluorinated alkyl acids (PFAAs). The majority of studies of PFAA-induced developmental toxicity have examined effects of perfluorooctane sulfonate (PFOS) or perfluorooctanoic acid (PFOA) a...

Short wavelength infrared optical windows for evaluation of benign and malignant tissues

NASA Astrophysics Data System (ADS)

Sordillo, Diana C.; Sordillo, Laura A.; Sordillo, Peter P.; Shi, Lingyan; Alfano, Robert R.

2017-04-01

There are three short wavelength infrared (SWIR) optical windows outside the conventionally used first near-infrared (NIR) window (650 to 950 nm). They occur in the 1000- to 2500-nm range and may be considered second, third, and fourth NIR windows. The second (1100 to 1350 nm) and third windows (1600 to 1870 nm) are now being explored through label-free linear and multiphoton imaging. The fourth window (2100 to 2350 nm) has been mostly ignored because of water absorption and the absence of sensitive detectors and ultrafast lasers. With the advent of new technology, use of window IV is now possible. Absorption and scattering properties of light through breast and prostate cancer, bone, lipids, and intralipid solutions at these windows were investigated. We found that breast and prostate cancer and bone have longer total attenuation lengths at NIR windows III and IV, whereas fatty tissues and intralipid have longest lengths at windows II and III. Since collagen is the major chromophore at 2100 and 2350 nm, window IV could be especially valuable in evaluating cancers and boney tissues, whereas windows II and III may be more useful for tissues with high lipid content. SWIR windows may be utilized as additional optical tools for the evaluation of collagen in tissues.

Short wavelength infrared optical windows for evaluation of benign and malignant tissues.

PubMed

Sordillo, Diana C; Sordillo, Laura A; Sordillo, Peter P; Shi, Lingyan; Alfano, Robert R

2017-04-01

There are three short wavelength infrared (SWIR) optical windows outside the conventionally used first near-infrared (NIR) window (650 to 950 nm). They occur in the 1000- to 2500-nm range and may be considered second, third, and fourth NIR windows. The second (1100 to 1350 nm) and third windows (1600 to 1870 nm) are now being explored through label-free linear and multiphoton imaging. The fourth window (2100 to 2350 nm) has been mostly ignored because of water absorption and the absence of sensitive detectors and ultrafast lasers. With the advent of new technology, use of window IV is now possible. Absorption and scattering properties of light through breast and prostate cancer, bone, lipids, and intralipid solutions at these windows were investigated. We found that breast and prostate cancer and bone have longer total attenuation lengths at NIR windows III and IV, whereas fatty tissues and intralipid have longest lengths at windows II and III. Since collagen is the major chromophore at 2100 and 2350 nm, window IV could be especially valuable in evaluating cancers and boney tissues, whereas windows II and III may be more useful for tissues with high lipid content. SWIR windows may be utilized as additional optical tools for the evaluation of collagen in tissues.

Narrow Escape of Interacting Diffusing Particles

NASA Astrophysics Data System (ADS)

Agranov, Tal; Meerson, Baruch

2018-03-01

The narrow escape problem deals with the calculation of the mean escape time (MET) of a Brownian particle from a bounded domain through a small hole on the domain's boundary. Here we develop a formalism which allows us to evaluate the nonescape probability of a gas of diffusing particles that may interact with each other. In some cases the nonescape probability allows us to evaluate the MET of the first particle. The formalism is based on the fluctuating hydrodynamics and the recently developed macroscopic fluctuation theory. We also uncover an unexpected connection between the narrow escape of interacting particles and thermal runaway in chemical reactors.

Parametric Dynamic Load Prediction of a Narrow Gauge Rocket Sled

DTIC Science & Technology

2006-12-01

Monorail λ Compared to Sled Tests.......................................................... 11 Figure 2.1 Application of Vertical λ to a Narrow Gauge sled...Three distinct sled configurations are used: monorail , dual rail wide gauge, and dual rail narrow gauge. Of the three, the narrow gauge...weight and the resulting value was termed λ. Monorail λ factor loading was first documented by Mixon (1971) where a few measured data points were

Measure Guideline: Window Repair, Rehabilitation, and Replacement

DOE Office of Scientific and Technical Information (OSTI.GOV)

Baker, P.

2012-12-01

This measure guideline provides information and guidance on rehabilitating, retrofitting, and replacing existing window assemblies in residential construction. The intent is to provide information regarding means and methods to improve the energy and comfort performance of existing wood window assemblies in a way that takes into consideration component durability, in-service operation, and long term performance of the strategies.

InP solar cell with window layer

NASA Technical Reports Server (NTRS)

Jain, Raj K. (Inventor); Landis, Geoffrey A. (Inventor)

1994-01-01

The invention features a thin light transmissive layer of the ternary semiconductor indium aluminum arsenide (InAlAs) as a front surface passivation or 'window' layer for p-on-n InP solar cells. The window layers of the invention effectively reduce front surface recombination of the object semiconductors thereby increasing the efficiency of the cells.

Voluntary and Involuntary Movements Widen the Window of Subjective Simultaneity.

PubMed

Arikan, B Ezgi; van Kemenade, Bianca M; Straube, Benjamin; Harris, Laurence R; Kircher, Tilo

2017-01-01

Forming a coherent percept of an event requires different sensory inputs originating from the event to be bound. Perceiving synchrony aids in binding of these inputs. In two experiments, we investigated how voluntary movements influence the perception of simultaneity, by measuring simultaneity judgments (SJs) for an audiovisual (AV) stimulus pair triggered by a voluntary button press. In Experiment 1, we manipulated contiguity between the action and its consequences by introducing delays between the button press and the AV stimulus pair. We found a widened window of subjective simultaneity (WSS) when the action-feedback relationship was time contiguous. Introducing a delay narrowed the WSS, suggesting that the wider WSS around the time of an action might facilitate perception of simultaneity. In Experiment 2, we introduced an involuntary condition using an externally controlled button to assess the influence of action-related predictive processes on SJs. We found a widened WSS around the action time, regardless of movement type, supporting the influence of causal relations in the perception of synchrony. Interestingly, the slopes of the psychometric functions in the voluntary condition were significantly steeper than the slopes in the involuntary condition, suggesting a role of action-related predictive mechanisms in making SJs more precise.

Voluntary and Involuntary Movements Widen the Window of Subjective Simultaneity

PubMed Central

Arikan, B. Ezgi; van Kemenade, Bianca M.; Straube, Benjamin; Harris, Laurence R.; Kircher, Tilo

2017-01-01

Forming a coherent percept of an event requires different sensory inputs originating from the event to be bound. Perceiving synchrony aids in binding of these inputs. In two experiments, we investigated how voluntary movements influence the perception of simultaneity, by measuring simultaneity judgments (SJs) for an audiovisual (AV) stimulus pair triggered by a voluntary button press. In Experiment 1, we manipulated contiguity between the action and its consequences by introducing delays between the button press and the AV stimulus pair. We found a widened window of subjective simultaneity (WSS) when the action-feedback relationship was time contiguous. Introducing a delay narrowed the WSS, suggesting that the wider WSS around the time of an action might facilitate perception of simultaneity. In Experiment 2, we introduced an involuntary condition using an externally controlled button to assess the influence of action-related predictive processes on SJs. We found a widened WSS around the action time, regardless of movement type, supporting the influence of causal relations in the perception of synchrony. Interestingly, the slopes of the psychometric functions in the voluntary condition were significantly steeper than the slopes in the involuntary condition, suggesting a role of action-related predictive mechanisms in making SJs more precise. PMID:28835813

A Supervised Approach to Windowing Detection on Dynamic Networks

DTIC Science & Technology

2017-07-01

A supervised approach to windowing detection on dynamic networks Benjamin Fish University of Illinois at Chicago 1200 W. Harrison St. Chicago...Using this framework, we introduce windowing algorithms that take a supervised approach : they leverage ground truth on training data to find a good...windowing of the test data. We compare the supervised approach to previous approaches and several baselines on real data. ACM Reference format: Benjamin

Context Switching with Multiple Register Windows: A RISC Performance Study

NASA Technical Reports Server (NTRS)

Konsek, Marion B.; Reed, Daniel A.; Watcharawittayakul, Wittaya

1987-01-01

Although previous studies have shown that a large file of overlapping register windows can greatly reduce procedure call/return overhead, the effects of register windows in a multiprogramming environment are poorly understood. This paper investigates the performance of multiprogrammed, reduced instruction set computers (RISCs) as a function of window management strategy. Using an analytic model that reflects context switch and procedure call overheads, we analyze the performance of simple, linearly self-recursive programs. For more complex programs, we present the results of a simulation study. These studies show that a simple strategy that saves all windows prior to a context switch, but restores only a single window following a context switch, performs near optimally.

State-of-the-art software for window energy-efficiency rating and labeling

DOE Office of Scientific and Technical Information (OSTI.GOV)

Arasteh, D.; Finlayson, E.; Huang, J.

1998-07-01

Measuring the thermal performance of windows in typical residential buildings is an expensive proposition. Not only is laboratory testing expensive, but each window manufacturer typically offers hundreds of individual products, each of which has different thermal performance properties. With over a thousand window manufacturers nationally, a testing-based rating system would be prohibitively expensive to the industry and to consumers. Beginning in the early 1990s, simulation software began to be used as part of a national program for rating window U-values. The rating program has since been expanded to include Solar Hear Gain Coefficients and is now being extended to annualmore » energy performance. This paper describes four software packages available to the public from Lawrence Berkeley National Laboratory (LBNL). These software packages are used to evaluate window thermal performance: RESFEN (for evaluating annual energy costs), WINDOW (for calculating a product`s thermal performance properties), THERM (a preprocessor for WINDOW that determines two-dimensional heat-transfer effects), and Optics (a preprocessor for WINDOW`s glass database). Software not only offers a less expensive means than testing to evaluate window performance, it can also be used during the design process to help manufacturers produce windows that will meet target specifications. In addition, software can show small improvements in window performance that might not be detected in actual testing because of large uncertainties in test procedures.« less

Pulse stretcher for narrow pulses

NASA Technical Reports Server (NTRS)

Lindsey, R. S., Jr. (Inventor)

1974-01-01

A pulse stretcher for narrow pulses is presented. The stretcher is composed of an analog section for processing each arriving analog pulse and a digital section with logic for providing command signals to the gates and switches in the analog section.

Ultrasound-guided identification of cardiac imaging windows.

PubMed

Liu, Garry; Qi, Xiu-Ling; Robert, Normand; Dick, Alexander J; Wright, Graham A

2012-06-01

Currently, the use of cine magnetic resonance imaging (MRI) to identify cardiac quiescent periods relative to the electrocardiogram (ECG) signal is insufficient for producing submillimeter-resolution coronary MR angiography (MRA) images. In this work, the authors perform a time series comparison between tissue Doppler echocardiograms of the interventricular septum (IVS) and concurrent biplane x-ray angiograms. Our results indicate very close agreement between the diastasis gating windows identified by both the IVS and x-ray techniques. Seven cath lab patients undergoing diagnostic angiograms were simultaneously scanned during a breath hold by ultrasound and biplane x-ray for six to eight heartbeats. The heart rate of each patient was stable. Dye was injected into either the left or right-coronary vasculature. The IVS was imaged using color tissue Doppler in an apical four-chamber view. Diastasis was estimated on the IVS velocity curve. On the biplane angiograms, proximal, mid, and distal regions were identified on the coronary artery (CA). Frame by frame correlation was used to derive displacement, and then velocity, for each region. The quiescent periods for a CA and its subsegments were estimated based on velocity. Using Pearson's correlation coefficient and Bland-Altman analysis, the authors compared the start and end times of the diastasis windows as estimated from the IVS and CA velocities. The authors also estimated the vessel blur across the diastasis windows of multiple sequential heartbeats of each patient. In total, 17 heartbeats were analyzed. The range of heart rate observed across patients was 47-79 beats per minute (bpm) with a mean of 57 bpm. Significant correlations (R > 0.99; p < 0.01) were observed between the IVS and x-ray techniques for the identification of the start and end times of diastasis windows. The mean difference in the starting times between IVS and CA quiescent windows was -12.0 ms. The mean difference in end times between IVS and CA

Developmental plasticity of mating calls enables acoustic communication in diverse environments

PubMed Central

Beckers, Oliver M; Schul, Johannes

2008-01-01

Male calls of the katydid Neoconocephalus triops exhibit substantial developmental plasticity in two parameters: (i) calls of winter males are continuous and lack the verse structure of summer calls and (ii) at equal temperatures, summer males produce calls with a substantially higher pulse rate than winter males. We raised female N. triops under conditions that reliably induced either summer or winter phenotype and tested their preferences for the call parameters that differ between summer and winter males. Neither generation was selective for the presence of verses, but females had strong preferences for pulse rates: only a narrow range of pulse rates was attractive. The attractive ranges did not differ between summer and winter females. Both male pulse rate and female preference for pulse rate changed with ambient temperature, but female preference changed more than the male calls. As a result, the summer call was attractive only at 25°C, whereas the slower winter call was attractive only at 20°C. Thus, developmental plasticity of male calls compensates for differences in temperature dependency between calls and preferences and enables the communication system to function in heterogeneous environments. The potential role of call plasticity during the invasion of new habitats is discussed. PMID:18302998

Intelligent windows using new thermotropic layers with long-term stability

NASA Astrophysics Data System (ADS)

Watanabe, Haruo

1995-08-01

This paper concerns the autonomous responsive type light adjustment window (intelligent windows) among smart windows which adjust the light upon receiving environmental energy. More specifically, this is a thermotropic window panel that laminates and seals a new type of highly viscous polymer aqueous solution gel. A conventional thermotropic window panel has never been put to practical use since the reversible change between the colorless, transparent state (water-clear) and translucent scattered state (paper-white) with uniformity was not possible. The change involved phase separation and generated non-uniformity. The author, after fundamental studies of hydrophobic bonding, successfully solved the problem by developing a polymer aqueous solution gel with amphiphatic molecule as the third component in addition to water and water-soluble polymer with hydrophobic radical, based on the molecular spacer concept. In addition, the author established peripheral technologies and succeeded in experimentally fabricating a panel type 'Affinity's Intelligent Window (AIW)' that has attained the level of practical use.

Space station proximity operations windows: Human factors design guidelines

NASA Technical Reports Server (NTRS)

Haines, Richard F.

1987-01-01

Proximity operations refers to all activities outside the Space Station which take place within a 1-km radius. Since there will be a large number of different operations involving manned and unmanned vehicles, single- and multiperson crews, automated and manually controlled flight, a wide variety of cargo, and construction/repair activities, accurate and continuous human monitoring of these operations from a specially designed control station on Space Station will be required. Total situational awareness will be required. This paper presents numerous human factors design guidelines and related background information for control windows which will support proximity operations. Separate sections deal with natural and artificial illumination geometry; all basic rendezvous vector approaches; window field-of-view requirements; window size; shape and placement criteria; window optical characteristics as they relate to human perception; maintenance and protection issues; and a comprehensive review of windows installed on U.S. and U.S.S.R. manned vehicles.

Development of a collapsible reinforced cylindrical space observation window

NASA Technical Reports Server (NTRS)

Khan, A. Q.

1971-01-01

Existing material technology was applied to the development of a collapsible transparent window suitable for manned spacecraft structures. The effort reported encompasses the evaluation of flame retardants intended for use in the window matrix polymer, evaluation of reinforcement angle which would allow for a twisting pantographing motion as the cylindrical window is mechanically collapsed upon itself, and evaluation of several reinforcement embedment methods. A fabrication technique was developed to produce a reinforced cylindrical space window of 45.7 cm diameter and 61.0 cm length. The basic technique involved the application of a clear film on a male-section mold; winding axial and girth reinforcements and vacuum casting the outer layer. The high-strength transparent window composite consisted of a polyether urethane matrix reinforced with an orthogonal pattern of black-coated carbon steel wire cable. A thin film of RTV silicone rubber was applied to both surfaces of the urethane. The flexibility, retraction system, and installation system are described.

Humeral windows in revision total elbow arthroplasty.

PubMed

Peach, Chris A; Salama, Amir; Stanley, David

2016-04-01

The use of cortical windows for revision elbow arthroplasty has not previously been widely reported. Their use aids safe revision of a well fixed humeral prosthesis and can be used in the setting of dislocation, periprosthetic fracture or aseptic loosening of the ulnar component. We describe our technique and results of cortical windows in the distal humerus for revision elbow arthroplasty surgery.

49 CFR 393.61 - Truck and truck tractor window construction.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 5 2010-10-01 2010-10-01 false Truck and truck tractor window construction. 393... REGULATIONS PARTS AND ACCESSORIES NECESSARY FOR SAFE OPERATION Glazing and Window Construction § 393.61 Truck and truck tractor window construction. Each truck and truck tractor (except trucks engaged in armored...

Arcjet exploratory tests of ARC optical window design for the AFE vehicle

NASA Technical Reports Server (NTRS)

Whiting, Ellis E.; Terrazas-Salinas, Imelda; Craig, Roger A.; Sobeck, Charles K.; Sarver, George L., III; Salerno, Louis J.; Love, Wendell; Maa, Scott; Covington, AL

1991-01-01

Tests were made in the 20 MW arc jet facility at the NASA ARC to determine the suitability of sapphire and fused silica as window materials for the Aeroassist Flight Experiment (AFE) entry vehicle. Twenty nine tests were made; 25 at a heating rate about 80 percent of that expected during the AFE entry and 4 at approximately the full, 100 percent AFE heating rate profile, that produces a temperature of about 2900 F on the surface of the tiles that protect the vehicle. These tests show that a conductively cooled window design using mechanical thermal contacts and sapphire is probably not practical. Cooling the window using mechanical thermal contacts produces thermal stresses in the sapphire that cause the window to crack. An insulated design using sapphire, that cools the window as little as possible, appears promising although some spectral data in the vacuum-ultra-violet (VUV) will be lost due to the high temperature reached by the sapphire. The surface of the insulated sapphire windows, tested at the 100 percent AFE heating rate, showed some slight ablation, and cracks appeared in two of three test windows. One small group of cracks were obviously caused by mechanical binding of the window in the assembly, which can be eliminated with improved design. Other cracks were long, straight, thin crystallographic cracks that have very little effect on the optical transmission of the window. Also, the windows did not fall apart along these crystallographic cracks when the windows were removed from their assemblies. Theoretical results from the thermal analysis computer program SINDA indicate that increasing the window thickness from 4 to 8 mm may enable surface ablation to be avoided. An insulated design using a fused silica window tested at the nominal AFE heating rate experienced severe ablation, thus fused silica is not considered to be an acceptable window material.

Bird-Window Collisions at a West-Coast Urban Park Museum: Analyses of Bird Biology and Window Attributes from Golden Gate Park, San Francisco.

PubMed

Kahle, Logan Q; Flannery, Maureen E; Dumbacher, John P

2016-01-01

Bird-window collisions are a major and poorly-understood generator of bird mortality. In North America, studies of this topic tend to be focused east of the Mississippi River, resulting in a paucity of data from the Western flyways. Additionally, few available data can critically evaluate factors such as time of day, sex and age bias, and effect of window pane size on collisions. We collected and analyzed 5 years of window strike data from a 3-story building in a large urban park in San Francisco, California. To evaluate our window collision data in context, we collected weekly data on local bird abundance in the adjacent parkland. Our study asks two overarching questions: first-what aspects of a bird's biology might make them more likely to fatally strike windows; and second, what characteristics of a building's design contribute to bird-window collisions. We used a dataset of 308 fatal bird strikes to examine the relationships of strikes relative to age, sex, time of day, time of year, and a variety of other factors, including mitigation efforts. We found that actively migrating birds may not be major contributors to collisions as has been found elsewhere. We found that males and young birds were both significantly overrepresented relative to their abundance in the habitat surrounding the building. We also analyzed the effect of external window shades as mitigation, finding that an overall reduction in large panes, whether covered or in some way broken up with mullions, effectively reduced window collisions. We conclude that effective mitigation or design will be required in all seasons, but that breeding seasons and migratory seasons are most critical, especially for low-rise buildings and other sites away from urban migrant traps. Finally, strikes occur throughout the day, but mitigation may be most effective in the morning and midday.

Bird-Window Collisions at a West-Coast Urban Park Museum: Analyses of Bird Biology and Window Attributes from Golden Gate Park, San Francisco

PubMed Central

Kahle, Logan Q.; Flannery, Maureen E.; Dumbacher, John P.

2016-01-01

Bird-window collisions are a major and poorly-understood generator of bird mortality. In North America, studies of this topic tend to be focused east of the Mississippi River, resulting in a paucity of data from the Western flyways. Additionally, few available data can critically evaluate factors such as time of day, sex and age bias, and effect of window pane size on collisions. We collected and analyzed 5 years of window strike data from a 3-story building in a large urban park in San Francisco, California. To evaluate our window collision data in context, we collected weekly data on local bird abundance in the adjacent parkland. Our study asks two overarching questions: first–what aspects of a bird’s biology might make them more likely to fatally strike windows; and second, what characteristics of a building’s design contribute to bird-window collisions. We used a dataset of 308 fatal bird strikes to examine the relationships of strikes relative to age, sex, time of day, time of year, and a variety of other factors, including mitigation efforts. We found that actively migrating birds may not be major contributors to collisions as has been found elsewhere. We found that males and young birds were both significantly overrepresented relative to their abundance in the habitat surrounding the building. We also analyzed the effect of external window shades as mitigation, finding that an overall reduction in large panes, whether covered or in some way broken up with mullions, effectively reduced window collisions. We conclude that effective mitigation or design will be required in all seasons, but that breeding seasons and migratory seasons are most critical, especially for low-rise buildings and other sites away from urban migrant traps. Finally, strikes occur throughout the day, but mitigation may be most effective in the morning and midday. PMID:26731417

AKI in the very elderly patients without preexisting chronic kidney disease: a comparison of 48-hour window and 7-day window for diagnosing AKI using the KDIGO criteria.

PubMed

Li, Qinglin; Zhao, Meng; Wang, Xiaodan

2018-01-01

To compare the differences between the Kidney Disease Improving Global Outcomes (KDIGO) criteria of the 48-hour window and the 7-day window in the diagnosis of acute kidney injury (AKI) in very elderly patients, as well as the relationship between the 48-hour and 7-day windows for diagnosis and 90-day mortality. We retrospectively enrolled very elderly patients (≥75 years old) from the geriatrics department of the Chinese PLA General Hospital between January 2007 and December 2015. AKI patients were divided into 48-hour and 7-day groups by their diagnosis criteria. AKI patients were divided into survivor and nonsurvivor groups by their outcomes within 90 days after diagnosis of AKI. In total, 652 patients were included in the final analysis. The median age of the cohort was 87 (84-91) years, the majority (623, 95.6%) of whom were male. Of the 652 AKI patients, 334 cases (51.2%) were diagnosed with AKI by the 48-hour window for diagnosis, while 318 cases (48.8%) were by the 7-day window for diagnosis. The 90-day mortality was 42.5% in patients with 48-hour window AKI and 24.2% in patients with 7-day window AKI. Kaplan-Meier curves showed that 90-day mortality was lower in the 7-day window AKI group than in the 48-hour window AKI group (log rank: P <0.001). Multivariate analysis by the Cox model revealed that 48-hour window for diagnosis hazard ratio (HR=1.818; 95% CI: 1.256-2.631; P =0.002) was associated with higher 90-day mortality. The 90-day mortality was higher in 48-hour window AKI than in 7-day window AKI in very elderly patients. The 48-hour KDIGO window definition may be less sensitive. The 48-hour KDIGO window definition is significantly better correlated with subsequent mortality and is, therefore, still appropriate for clinical use. Finding early, sensitive biomarkers of kidney damage is a future direction of research.

Radiation-transparent windows, method for imaging fluid transfers

DOEpatents

Shu, Deming [Darien, IL; Wang, Jin [Burr Ridge, IL

2011-07-26

A thin, x-ray-transparent window system for environmental chambers involving pneumatic pressures above 40 bar is presented. The window allows for x-ray access to such phenomena as fuel sprays injected into a pressurized chamber that mimics realistic internal combustion engine cylinder operating conditions.

Interoperability through standardization: Electronic mail, and X Window systems

NASA Technical Reports Server (NTRS)

Amin, Ashok T.

1993-01-01

Since the introduction of computing machines, there has been continual advances in computer and communication technologies and approaching limits. The user interface has evolved from a row of switches, character based interface using teletype terminals and then video terminals, to present day graphical user interface. It is expected that next significant advances will come in the availability of services, such as electronic mail and directory services, as the standards for applications are developed and in the 'easy to use' interfaces, such as Graphical User Interface for example Window and X Window, which are being standardized. Various proprietary electronic mail (email) systems are in use within organizations at each center of NASA. Each system provides email services to users within an organization, however the support for email services across organizations and across centers exists at centers to a varying degree and is often easy to use. A recent NASA email initiative is intended 'to provide a simple way to send email across organizational boundaries without disruption of installed base.' The initiative calls for integration of existing organizational email systems through gateways connected by a message switch, supporting X.400 and SMTP protocols, to create a NASA wide email system and for implementation of NASA wide email directory services based on OSI standard X.500. A brief overview of MSFC efforts as a part of this initiative are described. Window based graphical user interfaces make computers easy to use. X window protocol has been developed at Massachusetts Institute of Technology in 1984/1985 to provide uniform window based interface in a distributed computing environment with heterogenous computers. It has since become a standard supported by a number of major manufacturers. Z Windows systems, terminals and workstations, and X Window applications are becoming available. However impact of its use in the Local Area Network environment on the network

Theoretical vibro-acoustic modeling of acoustic noise transmission through aircraft windows

NASA Astrophysics Data System (ADS)

Aloufi, Badr; Behdinan, Kamran; Zu, Jean

2016-06-01

In this paper, a fully vibro-acoustic model for sound transmission across a multi-pane aircraft window is developed. The proposed model is efficiently applied for a set of window models to perform extensive theoretical parametric studies. The studied window configurations generally simulate the passenger window designs of modern aircraft classes which have an exterior multi-Plexiglas pane, an interior single acrylic glass pane and a dimmable glass ("smart" glass), all separated by thin air cavities. The sound transmission loss (STL) characteristics of three different models, triple-, quadruple- and quintuple-paned windows identical in size and surface density, are analyzed for improving the acoustic insulation performances. Typical results describing the influence of several system parameters, such as the thicknesses, number and spacing of the window panes, on the transmission loss are then investigated. In addition, a comparison study is carried out to evaluate the acoustic reduction capability of each window model. The STL results show that the higher frequencies sound transmission loss performance can be improved by increasing the number of window panels, however, the low frequency performance is decreased, particularly at the mass-spring resonances.

Round window closure affects cochlear responses to suprathreshold stimuli.

PubMed

Cai, Qunfeng; Whitcomb, Carolyn; Eggleston, Jessica; Sun, Wei; Salvi, Richard; Hu, Bo Hua

2013-12-01

The round window acts as a vent for releasing inner ear pressure and facilitating basilar membrane vibration. Loss of this venting function affects cochlear function, which leads to hearing impairment. In an effort to identify functional changes that might be used in clinical diagnosis of round window atresia, the current investigation was designed to examine how the cochlea responds to suprathreshold stimuli following round window closure. Prospective, controlled, animal study. A rat model of round window occlusion (RWO) was established. With this model, the thresholds of auditory brainstem responses (ABR) and the input/output (IO) functions of distortion product otoacoustic emissions (DPOAEs) and acoustic startle responses were examined. Round window closure caused a mild shift in the thresholds of the auditory brainstem response (13.5 ± 9.1 dB). It also reduced the amplitudes of the distortion product otoacoustic emissions and the slope of the input/output functions. This peripheral change was accompanied by a significant reduction in the amplitude, but not the threshold, of the acoustic startle reflex, a motor response to suprathreshold sounds. In addition to causing mild increase in the threshold of the auditory brainstem response, round window occlusion reduced the slopes of both distortion product otoacoustic emissions and startle reflex input/output functions. These changes differ from those observed for typical conductive or sensory hearing loss, and could be present in patients with round window atresia. However, future clinical observations in patients are needed to confirm these findings. Copyright © 2013 The American Laryngological, Rhinological and Otological Society, Inc.

Orthogonal sets of data windows constructed from trigonometric polynomials

NASA Technical Reports Server (NTRS)

Greenhall, C. A.

1989-01-01

Suboptimal, easily computable substitutes for the discrete prolate-spheroidal windows used by Thomson for spectral estimation are given. Trigonometric coefficients and energy leakages of the window polynomials are tabulated.

Low-E Storm Windows Gain Acceptance as a Home Weatherization Measure

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gilbride, Theresa L.; Cort, Katherine A.

This article for Home Energy Magazine describes work by the U.S. Department of Energy to develop low-emissivity storm windows as an energy efficiency-retrofit option for existing homes. The article describes the low-emissivity invisible silver metal coatings on the glass, which reflect heat back into the home in winter or back outside in summer and the benefits of low-e storm windows including insulation, air sealing, noise blocking, protection of antique windows, etc. The article also describes Pacific Northwest National Laboratory's efforts on behalf of DOE to overcome market barriers to adoption of the technology, including performance validation studies in the PNNLmore » Lab Homes, cost effectiveness analysis, production of reports, brochures, how-to guides on low-e storm window installation for the Building America Solution Center, and a video posted on YouTube. PNNL's efforts were reviewed by the Pacific Northwest Regional Technical Forum (RTF), which serves as the advisory board to the Pacific Northwest Electric Power Planning Council and Bonneville Power Administration. In late July 2015, the RTF approved the low-e storm window measure’s savings and specifications, a critical step in integrating low-e storm windows into energy-efficiency planning and utility weatherization and incentive programs. PNNL estimates that more than 90 million homes in the United States with single-pane or low-performing double-pane windows would benefit from the technology. Low-e storm windows are suitable not only for private residences but also for small commercial buildings, historic properties, and facilities that house residents, such as nursing homes, dormitories, and in-patient facilities. To further assist in the market transformation of low-e storm windows and other high-efficiency window attachments, DOE helped found the window Attachment Energy Rating Council (AERC) in 2015. AERC is an independent, public interest, non-profit organization whose mission is to rate

Catalog of Window Taper Functions for Sidelobe Control

DOE Office of Scientific and Technical Information (OSTI.GOV)

Doerry, Armin W.

Window taper functions of finite apertures are well-known to control undesirable sidelobes, albeit with performance trades. A plethora of various taper functions have been developed over the years to achieve various optimizations. We herein catalog a number of window functions, and com pare principal characteristics.

Writers Identification Based on Multiple Windows Features Mining

NASA Astrophysics Data System (ADS)

Fadhil, Murad Saadi; Alkawaz, Mohammed Hazim; Rehman, Amjad; Saba, Tanzila

2016-03-01

Now a days, writer identification is at high demand to identify the original writer of the script at high accuracy. The one of the main challenge in writer identification is how to extract the discriminative features of different authors' scripts to classify precisely. In this paper, the adaptive division method on the offline Latin script has been implemented using several variant window sizes. Fragments of binarized text a set of features are extracted and classified into clusters in the form of groups or classes. Finally, the proposed approach in this paper has been tested on various parameters in terms of text division and window sizes. It is observed that selection of the right window size yields a well positioned window division. The proposed approach is tested on IAM standard dataset (IAM, Institut für Informatik und angewandte Mathematik, University of Bern, Bern, Switzerland) that is a constraint free script database. Finally, achieved results are compared with several techniques reported in the literature.

Developmental Specificity in Targeting and Teaching Play Activities to Children with Pervasive Developmental Disorders

ERIC Educational Resources Information Center

Lifter, Karin; Ellis, James; Cannon, Barbara; Anderson, Stephen R.

2005-01-01

Developmentally specific play programs were designed for three children with pervasive developmental disorders being served in a home-based program. Using the Developmental Play Assessment, six activities for each of three adjacent developmentally sequenced play categories were targeted for direct instruction using different toy sets. A modified…

Waveguide transition with vacuum window for multiband dynamic nuclear polarization systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rybalko, Oleksandr; Bowen, Sean; Zhurbenko, Vitaliy

2016-05-15

A low loss waveguide transition section and oversized microwave vacuum window covering several frequency bands (94 GHz, 140 GHz, 188 GHz) is presented. The transition is compact and was optimized for multiband Dynamic Nuclear Polarization (DNP) systems in a full-wave simulator. The window is more broadband than commercially available windows, which are usually optimized for single band operation. It is demonstrated that high-density polyethylene with urethane adhesive can be used as a low loss microwave vacuum window in multiband DNP systems. The overall assembly performance and dimensions are found using full-wave simulations. The practical aspects of the window implementation inmore » the waveguide are discussed. To verify the design and simulation results, the window is tested experimentally at the three frequencies of interest.« less

The narrow pentaquark

DOE Office of Scientific and Technical Information (OSTI.GOV)

Diakonov, Dmitri

2007-02-27

The experimental status of the pentaquark searches is briefly reviewed. Recent null results by the CLAS collaboration are commented, and new strong evidence of a very narrow {theta}+ resonance by the DIANA collaboration is presented. On the theory side, I revisit the argument against the existence of the pentaquark - that of Callan and Klebanov - and show that actually a strong resonance is predicted in that approach, however its width is grossly overestimated. A recent calculation gives 2 MeV for the pentaquark width, and this number is probably still an upper bound.

VO₂ thermochromic smart window for energy savings and generation.

PubMed

Zhou, Jiadong; Gao, Yanfeng; Zhang, Zongtao; Luo, Hongjie; Cao, Chuanxiang; Chen, Zhang; Dai, Lei; Liu, Xinling

2013-10-24

The ability to achieve energy saving in architectures and optimal solar energy utilisation affects the sustainable development of the human race. Traditional smart windows and solar cells cannot be combined into one device for energy saving and electricity generation. A VO2 film can respond to the environmental temperature to intelligently regulate infrared transmittance while maintaining visible transparency, and can be applied as a thermochromic smart window. Herein, we report for the first time a novel VO2-based smart window that partially utilises light scattering to solar cells around the glass panel for electricity generation. This smart window combines energy-saving and generation in one device, and offers potential to intelligently regulate and utilise solar radiation in an efficient manner.

Sealed symmetric multilayered microelectronic device package with integral windows

DOEpatents

Peterson, Kenneth A.; Watson, Robert D.

2002-01-01

A sealed symmetric multilayered package with integral windows for housing one or more microelectronic devices. The devices can be a semiconductor chip, a CCD chip, a CMOS chip, a VCSEL chip, a laser diode, a MEMS device, or a IMEMS device. The multilayered package can be formed of a low-temperature cofired ceramic (LTCC) or high-temperature cofired ceramic (HTCC) multilayer processes with the windows being simultaneously joined (e.g. cofired) to the package body during LTCC or HTCC processing. The microelectronic devices can be flip-chip bonded and oriented so that the light-sensitive sides are optically accessible through the windows. The result is a compact, low-profile, sealed symmetric package, having integral windows that can be hermetically-sealed.

Recognition of the Multi Specularity Objects using the Eigen-Window,

DTIC Science & Technology

1996-02-29

analysis to each eigen-window [21]. The basic idea is that, even if some of the windows are occluded, the remaining windows are still effective and can...K.Ikeuchi, “The Machanical Manipulation of Randomly Oriented Parts”, Scientific American, Vol.251, No.2, pp.100-111, 1984. [5] S.A.Hutchinson and A.C.Kak

24 CFR 3280.106 - Exit facilities; egress windows and devices.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false Exit facilities; egress windows and... § 3280.106 Exit facilities; egress windows and devices. (a) Every room designed expressly for sleeping purposes, unless it has an exit door (see § 3280.105), shall have at least one outside window or approved...

The Domain of Developmental Psychopathology.

ERIC Educational Resources Information Center

Sroufe, L. Alan; Rutter, Michael

1984-01-01

Describes how developmental psychopathology differs from related disciplines, including abnormal psychology, psychiatry, clinical child psychology, and developmental psychology. Points out propositions underlying a developmental perspective and discusses implications for research in developmental psychopathology. (Author/RH)

Defining window-boundaries for genomic analyses using smoothing spline techniques

DOE PAGES

Beissinger, Timothy M.; Rosa, Guilherme J.M.; Kaeppler, Shawn M.; ...

2015-04-17

High-density genomic data is often analyzed by combining information over windows of adjacent markers. Interpretation of data grouped in windows versus at individual locations may increase statistical power, simplify computation, reduce sampling noise, and reduce the total number of tests performed. However, use of adjacent marker information can result in over- or under-smoothing, undesirable window boundary specifications, or highly correlated test statistics. We introduce a method for defining windows based on statistically guided breakpoints in the data, as a foundation for the analysis of multiple adjacent data points. This method involves first fitting a cubic smoothing spline to the datamore » and then identifying the inflection points of the fitted spline, which serve as the boundaries of adjacent windows. This technique does not require prior knowledge of linkage disequilibrium, and therefore can be applied to data collected from individual or pooled sequencing experiments. Moreover, in contrast to existing methods, an arbitrary choice of window size is not necessary, since these are determined empirically and allowed to vary along the genome.« less

Transmission in near-infrared optical windows for deep brain imaging.

PubMed

Shi, Lingyan; Sordillo, Laura A; Rodríguez-Contreras, Adrián; Alfano, Robert

2016-01-01

Near-infrared (NIR) radiation has been employed using one- and two-photon excitation of fluorescence imaging at wavelengths 650-950 nm (optical window I) for deep brain imaging; however, longer wavelengths in NIR have been overlooked due to a lack of suitable NIR-low band gap semiconductor imaging detectors and/or femtosecond laser sources. This research introduces three new optical windows in NIR and demonstrates their potential for deep brain tissue imaging. The transmittances are measured in rat brain tissue in the second (II, 1,100-1,350 nm), third (III, 1,600-1,870 nm), and fourth (IV, centered at 2,200 nm) NIR optical tissue windows. The relationship between transmission and tissue thickness is measured and compared with the theory. Due to a reduction in scattering and minimal absorption, window III is shown to be the best for deep brain imaging, and windows II and IV show similar but better potential for deep imaging than window I. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Identifying a Window of Vulnerability during Fetal Development in a Maternal Iron Restriction Model

PubMed Central

Mihaila, Camelia; Schramm, Jordan; Strathmann, Frederick G.; Lee, Dawn L.; Gelein, Robert M.

2011-01-01

It is well acknowledged from observations in humans that iron deficiency during pregnancy can be associated with a number of developmental problems in the newborn and developing child. Due to the obvious limitations of human studies, the stage during gestation at which maternal iron deficiency causes an apparent impairment in the offspring remains elusive. In order to begin to understand the time window(s) during pregnancy that is/are especially susceptible to suboptimal iron levels, which may result in negative effects on the development of the fetus, we developed a rat model in which we were able to manipulate and monitor the dietary iron intake during specific stages of pregnancy and analyzed the developing fetuses. We established four different dietary-feeding protocols that were designed to render the fetuses iron deficient at different gestational stages. Based on a functional analysis that employed Auditory Brainstem Response measurements, we found that maternal iron restriction initiated prior to conception and during the first trimester were associated with profound changes in the developing fetus compared to iron restriction initiated later in pregnancy. We also showed that the presence of iron deficiency anemia, low body weight, and changes in core body temperature were not defining factors in the establishment of neural impairment in the rodent offspring. Our data may have significant relevance for understanding the impact of suboptimal iron levels during pregnancy not only on the mother but also on the developing fetus and hence might lead to a more informed timing of iron supplementation during pregnancy. PMID:21423661

Exclusive queueing model including the choice of service windows

NASA Astrophysics Data System (ADS)

Tanaka, Masahiro; Yanagisawa, Daichi; Nishinari, Katsuhiro

2018-01-01

In a queueing system involving multiple service windows, choice behavior is a significant concern. This paper incorporates the choice of service windows into a queueing model with a floor represented by discrete cells. We contrived a logit-based choice algorithm for agents considering the numbers of agents and the distances to all service windows. Simulations were conducted with various parameters of agent choice preference for these two elements and for different floor configurations, including the floor length and the number of service windows. We investigated the model from the viewpoint of transit times and entrance block rates. The influences of the parameters on these factors were surveyed in detail and we determined that there are optimum floor lengths that minimize the transit times. In addition, we observed that the transit times were determined almost entirely by the entrance block rates. The results of the presented model are relevant to understanding queueing systems including the choice of service windows and can be employed to optimize facility design and floor management.

Galaxy properties from J-PAS narrow-band photometry

NASA Astrophysics Data System (ADS)

Mejía-Narváez, A.; Bruzual, G.; Magris, C. G.; Alcaniz, J. S.; Benítez, N.; Carneiro, S.; Cenarro, A. J.; Cristóbal-Hornillos, D.; Dupke, R.; Ederoclite, A.; Marín-Franch, A.; de Oliveira, C. Mendes; Moles, M.; Sodre, L.; Taylor, K.; Varela, J.; Ramió, H. Vázquez

2017-11-01

We study the consistency of the physical properties of galaxies retrieved from spectral energy distribution (SED) fitting as a function of spectral resolution and signal-to-noise ratio (SNR). Using a selection of physically motivated star formation histories, we set up a control sample of mock galaxy spectra representing observations of the local Universe in high-resolution spectroscopy, and in 56 narrow-band and 5 broad-band photometry. We fit the SEDs at these spectral resolutions and compute their corresponding stellar mass, the mass- and luminosity-weighted age and metallicity, and the dust extinction. We study the biases, correlations and degeneracies affecting the retrieved parameters and explore the role of the spectral resolution and the SNR in regulating these degeneracies. We find that narrow-band photometry and spectroscopy yield similar trends in the physical properties derived, the former being considerably more precise. Using a galaxy sample from the Sloan Digital Sky Survey (SDSS), we compare more realistically the results obtained from high-resolution and narrow-band SEDs (synthesized from the same SDSS spectra) following the same spectral fitting procedures. We use results from the literature as a benchmark to our spectroscopic estimates and show that the prior probability distribution functions, commonly adopted in parametric methods, may introduce biases not accounted for in a Bayesian framework. We conclude that narrow-band photometry yields the same trend in the age-metallicity relation in the literature, provided it is affected by the same biases as spectroscopy, albeit the precision achieved with the latter is generally twice as large as with the narrow-band, at SNR values typical of the different kinds of data.

Surgical anatomy of the round window-Implications for cochlear implantation.

PubMed

Luers, J C; Hüttenbrink, K B; Beutner, D

2018-04-01

The round window is an important portal for the application of active hearing aids and cochlear implants. The anatomical and topographical knowledge about the round window region is a prerequisite for successful insertion for a cochlear implant electrode. To sum up current knowledge about the round window anatomy and to give advice to the cochlear implant surgeon for optimal placement of an electrode. Systematic Medline search. Search term "round window[Title]" with no date restriction. Only publications in the English Language were included. All abstracts were screened for relevance, that is a focus on surgical anatomy of the round window. The search results were supplemented with hand searching of selected reviews and reference lists from included studies. Subjective assessment. There is substantial variability in size and shape of the round window. The round window is regarded as the most reliable surgical landmark to safely locate the scala tympani. Factors affecting the optimal trajectory line for atraumatic electrode insertion are anatomy of the round window, the anatomy of the intracochlear hook region and the variable orientation and size of the cochlea's basal turn. The very close relation to the sensitive inner ear structures necessitates a thorough anatomic knowledge and careful insertion technique, especially when implanting patients with residual hearing. In order to avoid electrode migration between the scalae and to achieve protect the modiolus and the basilar membrane, it is recommended to aim for an electrode insertion vector from postero-superior to antero-inferior. © 2017 John Wiley & Sons Ltd.

Developmental and functional outcomes in children with global developmental delay or developmental language impairment.

PubMed

Shevell, Michael; Majnemer, Annette; Platt, Robert W; Webster, Richard; Birnbaum, Rena

2005-10-01

Preschool children diagnosed with either global developmental delay (GDD) or developmental language impairment (DLI) were reassessed during their early school years with standardized developmental (Battelle Developmental Inventory [BDI]) and functional (Vineland Adaptive Behavior Scale [VABS]) outcome measures. Of an original cohort of 99 children with GDD and 70 children with DLI assessed and diagnosed at a mean age of 3 years 5 months (SD 1.1) and 3 years 7 months (SD 0.7) respectively, 48 children (34 [71%] males) with GDD and 43 children (36 [84%] males) with DLI were reassessed at a mean age of 7 years 4 months (SD 0.9) and 7 years 5 months (SD 0.7) respectively. The overall total mean BDI score for children with GDD was 66.4 (SD 4.3) versus 71.9 (SD 8.2) for children with DLI (p=0.002). On each subdomain of the BDI, except communication, mean scores for the GDD group were significantly lower than for the DLI group (p<0.05). Similarly, the VABS total score for the GDD group was significantly lower than for the DLI group (p<0.001). For each subdomain of the VABS, the GDD group scored significantly lower than the DLI group (p<0.001). The proportion of children falling below meaningful cut-offs on the outcome measures selected was significantly higher for those initially diagnosed with GDD. Preschool diagnosis of either GDD or DLI has later prognostic validity with regard to persisting developmental and functional deficits.

Fourth near-infrared optical window for assessment of bone and other tissues

NASA Astrophysics Data System (ADS)

Sordillo, Diana C.; Sordillo, Laura A.; Sordillo, Peter P.; Alfano, Robert R.

2016-02-01

Recently, additional near-infrared (NIR) optical windows beyond the conventional first therapeutic window have been utilized for deep tissue imaging through scattering media. Biomedical applications using a second optical window (1100 to 1300 nm) and a third (1600 to 1870 nm) are emerging. A fourth window (2100 to 2300 nm) has been largely ignored due to high water absorption and a lack of high sensitivity imaging detectors and ultrafast laser sources. In this study, optical properties of bone in this fourth NIR optical window, were investigated. Results were compared to those seen at the first, second and third windows, and are consistent with our previous work on malignant and benign breast and prostate tissues. Bone and malignant tissues showed highest uptake in the third and fourth windows. As collagen is a major chromophore with prominent spectral peaks between 2100 and 2300 nm, it may be that the fourth optical window is particularly useful for studying tissues with a higher collagen content, such as bone or malignant tumors.

Imaging windows for long-term intravital imaging: General overview and technical insights.

PubMed

Alieva, Maria; Ritsma, Laila; Giedt, Randy J; Weissleder, Ralph; van Rheenen, Jacco

2014-01-01

Intravital microscopy is increasingly used to visualize and quantitate dynamic biological processes at the (sub)cellular level in live animals. By visualizing tissues through imaging windows, individual cells (e.g., cancer, host, or stem cells) can be tracked and studied over a time-span of days to months. Several imaging windows have been developed to access tissues including the brain, superficial fascia, mammary glands, liver, kidney, pancreas, and small intestine among others. Here, we review the development of imaging windows and compare the most commonly used long-term imaging windows for cancer biology: the cranial imaging window, the dorsal skin fold chamber, the mammary imaging window, and the abdominal imaging window. Moreover, we provide technical details, considerations, and trouble-shooting tips on the surgical procedures and microscopy setups for each imaging window and explain different strategies to assure imaging of the same area over multiple imaging sessions. This review aims to be a useful resource for establishing the long-term intravital imaging procedure.

Characterization and gene cloning of the rice (Oryza sativa L.) dwarf and narrow-leaf mutant dnl3.

PubMed

Shi, L; Wei, X J; Adedze, Y M N; Sheng, Z H; Tang, S Q; Hu, P S; Wang, J L

2016-09-16

The dwarf and narrow-leaf rice (Oryza sativa L.) mutant dnl3 was isolated from the Japonica cultivar Zhonghua 11 (wild-type). dnl3 exhibited pleiotropic developmental defects. The narrow-leaf phenotype resulted from a marked reduction in the number of vascular bundles, while the dwarf stature was caused by the formation of foreshortened internodes and a reduced number of parenchyma cells. The suggestion that cell division is impaired in the mutant was consistent with the transcriptional behavior of various genes associated with cell division. The mutant was less responsive to exogenously supplied gibberellic acid than the wild-type, and profiling the transcription of genes involved in gibberellin synthesis and response revealed that a lesion in the mutant affected gibberellin signal transduction. The dnl3 phenotype was inherited as a single-dominant gene, mapping within a 19.1-kb region of chromosome 12, which was found to harbor three open reading frames. Resequencing the open reading frames revealed that the mutant carried an allele at one of the three genes that differed from the wild-type sequence by 2-bp deletions; this gene encoded a cellulose synthase-like D4 (CSLD4) protein. Therefore, OsCSLD4 is a candidate gene for DNL3. DNL3 was expressed in all of the rice organs tested at the heading stage, particularly in the leaves, roots, and culms. These results suggest that DNL3 plays important roles in rice leaf morphogenesis and vegetative development.

The Effect of Divided Attention on Emotion-Induced Memory Narrowing

PubMed Central

Steinmetz, Katherine R. Mickley; Waring, Jill D.; Kensinger, Elizabeth A.

2014-01-01

Individuals are more likely to remember emotional than neutral information, but this benefit does not always extend to the surrounding background information. This memory narrowing is theorized to be linked to the availability of attentional resources at encoding. In contrast to the predictions of this theoretical account, altering participants’ attentional resources at encoding, by dividing attention, did not affect the emotion-induced memory narrowing. Attention was divided using three separate manipulations: a digit ordering task (Experiment 1), an arithmetic task (Experiment 2), and an auditory discrimination task (Experiment 3). Across all three experiments, divided attention decreased memory across-the-board but did not affect the degree of memory narrowing. These findings suggest that theories to explain memory narrowing must be expanded to include other potential mechanisms beyond limitations of attentional resources. PMID:24295041

The effect of divided attention on emotion-induced memory narrowing.

PubMed

Mickley Steinmetz, Katherine R; Waring, Jill D; Kensinger, Elizabeth A

2014-01-01

Individuals are more likely to remember emotional than neutral information, but this benefit does not always extend to the surrounding background information. This memory narrowing is theorised to be linked to the availability of attentional resources at encoding. In contrast to the predictions of this theoretical account, altering participants' attentional resources at encoding by dividing attention did not affect emotion-induced memory narrowing. Attention was divided using three separate manipulations: a digit ordering task (Experiment 1), an arithmetic task (Experiment 2) and an auditory discrimination task (Experiment 3). Across all three experiments, divided attention decreased memory across the board but did not affect the degree of memory narrowing. These findings suggest that theories to explain memory narrowing must be expanded to include other potential mechanisms beyond the limitations of attentional resources.

Access to Microsoft Windows 95 for Persons with Low Vision: An Overview.

ERIC Educational Resources Information Center

Shragai, Y.

1995-01-01

This article examines Windows 95, pointing out differences and improvements from Windows 3.1 for persons with low vision. Windows 95 is seen as providing substantially greater accessibility than Windows 3.1, though the graphical user interface may still pose serious problems for some users with low vision. (DB)

Bayesian Face Recognition and Perceptual Narrowing in Face-Space

ERIC Educational Resources Information Center

Balas, Benjamin

2012-01-01

During the first year of life, infants' face recognition abilities are subject to "perceptual narrowing", the end result of which is that observers lose the ability to distinguish previously discriminable faces (e.g. other-race faces) from one another. Perceptual narrowing has been reported for faces of different species and different races, in…

16 CFR 455.2 - Consumer sales-window form.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Consumer sales-window form. 455.2 Section 455.2 Commercial Practices FEDERAL TRADE COMMISSION TRADE REGULATION RULES USED MOTOR VEHICLE TRADE REGULATION RULE § 455.2 Consumer sales—window form. (a) General duty. Before you offer a used vehicle for...

Round window chamber and fustis: endoscopic anatomy and surgical implications.

PubMed

Marchioni, Daniele; Soloperto, Davide; Colleselli, Elena; Tatti, Maria Fatima; Patel, Nirmal; Jufas, Nicholas

2016-11-01

The round window region is of critical importance in the anatomy of the middle ear. The aim of this paper is to describe its anatomy from an endoscopic point of view, emphasizing structures that have important surgical implications, in particular the fustis and the subcochlear canaliculus. The fustis, a smooth bony structure that forms the floor of the round window region, is a constant and important structure. It seems to indicate the round window membrane and the correct position of scala tympani. A structure connecting the round window region to the petrous apex, named the subcochlear canaliculus, is also described. A retrospective review of video recordings of endoscopic dissection and surgical procedures, carried out between June 2014 and February 2015, was conducted across two Tertiary university referral centers. A total of 42 dissections were analyzed in the study. We observed the fustis in all the cases and we identify two different anatomical conformations. The subcochlear canaliculus was found in 81.0 %, with a pneumatization direct to the petrous apex in 47.7 %. Conformation and limits of the round window niche may influence the surgical view of the round window membrane. Endoscopic approaches allow a very detailed view, which enables a comprehensive exploration of the round window region. Accurate knowledge of the anatomical relationships of this region has important advantages during middle ear surgery.

Light transfer through windows with external condensation

NASA Astrophysics Data System (ADS)

Zhu, Keyong; Li, Shaoling; Pilon, Laurent

2018-03-01

This study investigates systematically light transfer through windows supporting cap-shaped droplets on their external face. The presence of such droplets may have negative effects on the conversion efficiency of solar cells, distorts image quality of lenses, or hinders visibility through windows and windshields. Here, the directional-hemispherical transmittance was predicted by the Monte Carlo ray-tracing method. The droplets were monodisperse or polydisperse randomly distributed on the outside face of optically smooth windows. For nonabsorbing droplets, the diameter and size distribution did not have a significant effect on the window directional-hemispherical transmittance. The latter was nearly independent of contact angle for incident angle θi ≤ 30°. However, the directional-hemispherical transmittance decreased monotonously with increasing incident angle and droplet contact angle for contact angle θc ≤ 70° to reach a minimum at a contact angle θc,min beyond which it increased with increasing contact angle before reaching a plateau at large contact angles. This was attributed to total internal reflection at the back window/air and droplet/air interfaces. For absorbing droplets, the normal-hemispherical transmittance decreased significantly with increasing droplet contact angle, mean diameter, polydispersity, and projected surface area coverage due to strong absorption within the droplets. Moreover, the normal-hemispherical transmittance decreased with increasing contact angle for θc< 90° and remained constant and independent of the droplets' absorption index, mean diameter, and contact angle for θc ≥ 90°. Finally, Analytical expressions for the upper and lower bounds of the normal-hemispherical transmittance as a function of droplet contact angle, optical properties, and projected surface area coverage were derived.

Developmental Neurotoxicology: History and Outline of Developmental Neurotoxicity Study Guidelines.

EPA Science Inventory

The present work provides a brief review of basic concepts in developmental neurotoxicology, as well as current representative testing guidelines for evaluating developmental neurotoxicity (DNT) of xenobiotics. Historically, DNT was initially recognized as a “functional” teratoge...

Comparison of the validity of direct pediatric developmental evaluation versus developmental screening by parent report

USDA-ARS?s Scientific Manuscript database

To compare the validity of direct pediatric developmental evaluation with developmental screening by parent report, parents completed a developmental screen (the Child Development Review), a pediatrician performed a direct developmental evaluation (Capute Scales), and a psychologist administered the...

Apparatus for insulating windows and the like

DOEpatents

Mitchell, R.A.

1984-06-19

Apparatus for insulating window openings through walls and the like includes a thermal shutter, a rail for mounting the shutter adjacent to the window opening and a coupling for connecting the shutter to the rail. The thermal shutter includes an insulated panel adhered to frame members which surround the periphery of the panel. The frame members include a hard portion for providing the frame and a soft portion for providing a seal with that portion of the wall adjacent to the periphery of the opening. The coupling means is preferably integral with the attachment rail. According to a preferred embodiment, the coupling means includes a continuous hinge of reduced thickness. The thermal shutter can be permanently attached, hinged, bi-folded, or sliding with respect to the window and wall. A distribution method is to market the apparatus in kit'' form. 11 figs.

Apparatus for insulating windows and the like

DOEpatents

Mitchell, Robert A.

1984-01-01

Apparatus for insulating window openings through walls and the like includes a thermal shutter, a rail for mounting the shutter adjacent to the window opening and a coupling for connecting the shutter to the rail. The thermal shutter includes an insulated panel adhered to frame members which surround the periphery of the panel. The frame members include a hard portion for providing the frame and a soft portion for providing a seal with that portion of the wall adjacent to the periphery of the opening. The coupling means is preferably integral with the attachment rail. According to a preferred embodiment, the coupling means includes a continuous hinge of reduced thickness. The thermal shutter can be permanently attached, hinged, bi-folded, or sliding with respect to the window and wall. A distribution method is to market the apparatus in "kit" form.

Windows to Art Excitement.

ERIC Educational Resources Information Center

Laird, Shirley; Crumpecker, Cheryl

2003-01-01

Describes an art project that aimed to bring more attention to an art program. Explains that the students created themed murals on the windows of the art classroom, such as a "Jungle,""Ocean,""Masterpiece Paintings," and "Rainforest Tree Frogs." Discusses how the murals were created. (CMK)

Very narrow excited Ωc baryons

NASA Astrophysics Data System (ADS)

Karliner, Marek; Rosner, Jonathan L.

2017-06-01

Recently, LHCb reported the discovery of five extremely narrow excited Ωc baryons decaying into Ξc+K-. We interpret these baryons as bound states of a c quark and a P -wave s s diquark. For such a system, there are exactly five possible combinations of spin and orbital angular momentum. The narrowness of the states could be a signal that it is hard to pull apart the two s quarks in a diquark. We predict two of spin 1 /2 , two of spin 3 /2 , and one of spin 5 /2 , all with negative parity. Of the five states, two can decay in S -wave, and three can decay in D -wave. Some of the D -wave states might be narrower than the S -wave states. We discuss the relations among the five masses expected in the quark model and the likely spin assignments, and we compare them with the data. A similar pattern is expected for negative-parity excited Ωb states. An alternative interpretation is noted in which the heaviest two states are 2 S excitations with JP=1 /2+ and 3 /2+, while the lightest three are those with JP=3 /2- , 3 /2- , 5 /2- , expected to decay via D -waves. In this case, we expect JP=1 /2- Ωc states around 2904 and 2978 MeV.

Defect window analysis by using SEM-contour based shape quantifying method for sub-20nm node production

NASA Astrophysics Data System (ADS)

Hibino, Daisuke; Hsu, Mingyi; Shindo, Hiroyuki; Izawa, Masayuki; Enomoto, Yuji; Lin, J. F.; Hu, J. R.

2013-04-01

The impact on yield loss due to systematic defect which remains after Optical Proximity Correction (OPC) modeling has increased, and achieving an acceptable yield has become more difficult in the leading technology beyond 20 nm node production. Furthermore Process-Window has become narrow because of the complexity of IC design and less process margin. In the past, the systematic defects have been inspected by human-eyes. However the judgment by human-eyes is sometime unstable and not accurate. Moreover an enormous amount of time and labor will have to be expended on the one-by-one judgment for several thousands of hot-spot defects. In order to overcome these difficulties and improve the yield and manufacturability, the automated system, which can quantify the shape difference with high accuracy and speed, is needed. Inspection points could be increased for getting higher yield, if the automated system achieves our goal. Defect Window Analysis (DWA) system by using high-precision-contour extraction from SEM image on real silicon and quantifying method which can calculate the difference between defect pattern and non-defect pattern automatically, which was developed by Hitachi High-Technologies, has been applied to the defect judgment instead of the judgment by human-eyes. The DWA result which describes process behavior might be feedback to design or OPC or mask. This new methodology and evaluation results will be presented in detail in this paper.

HRCT Correlation with Round Window Identification during Cochlear Implantation in Children.

PubMed

Pendem, Sai Kiran; Rangasami, Rajeswaran; Arunachalam, Ravi Kumar; Mohanarangam, Venkata Sai Pulivadulu; Natarajan, Paarthipan

2014-01-01

To determine the accuracy of High Resolution Computer Tomography (HRCT) temporal bone measurements in predicting the actual visualization of round window niche as viewed through posterior tympanotomy (i.e. facial recess). This is a prospective study of 37 cochlear implant candidates, aged between 1and 6 years, who were referred for HRCT temporal bone during the period December 2013 to July 2014. Cochlear implantation was done in 37 children (25 in the right ear and 12 in the left ear). The distance between the short process of incus and the round window niche and the distance between the oval window and the round window niche were measured preoperatively on sub-millimeter (0.7 mm) HRCT images. We classified the visibility of round window niche based on the surgical view (i.e. through posterior tympanotomy) during surgery into three types: 1) Type 1- fully visible, 2) Type 2- partially visible, and 3) Type 3- difficult to visualize. The preoperative HRCT measurements were used to predict the type of visualization of round window niche before surgery and correlated with the findings during surgery. The mean and standard deviation for the distance between the short process of incus and the round window niche and for the distance between the oval window and the round window niche for Types 1, 2, and 3 were 8.5 ± 0.2 mm and 3.2 ± 0.2 mm, 8.0 ± 0.4 mm and 3.8 ± 0.2 mm, 7.5 ± 0.2 mm and 4.4 ± 0.2 mm respectively, and showed statistically significant difference (P < 0.01) between them. The preoperative HRCT measurements had a sensitivity and specificity of 92.3% and 96.2%, respectively, in determining the actual visualization of round window niche. This study shows preoperative HRCT temporal bone measurements are useful in predicting the actual visualization of round window niche as viewed through posterior tympanotomy.

Advances in low-cost long-wave infrared polymer windows

NASA Astrophysics Data System (ADS)

Weimer, Wayne A.; Klocek, Paul

1999-07-01

Recent improvements in engineered polymeric material compositions and advances in processing methodologies developed and patented at Raytheon Systems Company have produced long wave IR windows at exceptionally low costs. These UV stabilized, high strength windows incorporating subwavelength structured antireflection surfaces are enabling IR imaging systems to penetrate commercial markets and will reduce the cost of systems delivered to the military. The optical and mechanical properties of these windows will be discussed in detail with reference to the short and long-term impact on military IR imaging systems.

Lobster eye as a collector for water window microscopy

NASA Astrophysics Data System (ADS)

Pina, L.; Maršíková, V.; Inneman, A.; Nawaz, M. F.; Jančárek, A.; Havlíková, R.

2017-08-01

Imaging in EUV, SXR and XR spectral bands of radiation is of increasing interest. Material science, biology and hot plasma are examples of relevant fast developing areas. Applications include spectroscopy, astrophysics, Soft X-ray Ray metrology, Water Window microscopy, radiography and tomography. Especially Water Window imaging has still not fully recognized potential in biology and medicine microscopy applications. Theoretical study and design of Lobster Eye (LE) optics as a collector for water window (WW) microscopy and comparison with a similar size ellipsoidal mirror condensor are presented.

Design and Verification of Critical Pressurised Windows for Manned Spaceflight

NASA Astrophysics Data System (ADS)

Lamoure, Richard; Busto, Lara; Novo, Francisco; Sinnema, Gerben; Leal, Mendes M.

2014-06-01

The Window Design for Manned Spaceflight (WDMS) project was tasked with establishing the state-of-art and explore possible improvements to the current structural integrity verification and fracture control methodologies for manned spacecraft windows.A critical review of the state-of-art in spacecraft window design, materials and verification practice was conducted. Shortcomings of the methodology in terms of analysis, inspection and testing were identified. Schemes for improving verification practices and reducing conservatism whilst maintaining the required safety levels were then proposed.An experimental materials characterisation programme was defined and carried out with the support of the 'Glass and Façade Technology Research Group', at the University of Cambridge. Results of the sample testing campaign were analysed, post-processed and subsequently applied to the design of a breadboard window demonstrator.Two Fused Silica glass window panes were procured and subjected to dedicated analyses, inspection and testing comprising both qualification and acceptance programmes specifically tailored to the objectives of the activity.Finally, main outcomes have been compiled into a Structural Verification Guide for Pressurised Windows in manned spacecraft, incorporating best practices and lessons learned throughout this project.

Bird-Window Collisions: A Critical Animal Welfare and Conservation Issue.

PubMed

Klem, Daniel

2015-01-01

Sheet glass and plastic in the form of clear and reflective windows are universally lethal to birds. Reasonable interpretation of available scientific evidence describes windows as a principal human-associated avian mortality factor that is an indiscriminant killer of common species as well as species of conservation concern. A conservative toll estimates 1 billion or more annual fatalities in the United States alone. The injury and death from birds striking windows are foreseeable and preventable, but the most promising legal measures and commercial products are not being applied or made available to protect defenseless victims. Avian window casualties are important for birds and people, and they have nonhuman animal welfare, biodiversity, sustainability, legal, and ethical and moral value justifying responsible human action. Preventing this unintended and unwanted lethal hazard for free-flying birds should be an obligation. Short-term solutions include retrofitting existing panes with a variety of proven measures that among others include applying various materials to cover the outside surface of windows. Long-term solutions include current and proposed bird-safe sheet glass and plastic for remodeling and new construction that have patterns that transform windows into barriers that birds see and avoid.

Fully automatic time-window selection using machine learning for global adjoint tomography

NASA Astrophysics Data System (ADS)

Chen, Y.; Hill, J.; Lei, W.; Lefebvre, M. P.; Bozdag, E.; Komatitsch, D.; Tromp, J.

2017-12-01

Selecting time windows from seismograms such that the synthetic measurements (from simulations) and measured observations are sufficiently close is indispensable in a global adjoint tomography framework. The increasing amount of seismic data collected everyday around the world demands "intelligent" algorithms for seismic window selection. While the traditional FLEXWIN algorithm can be "automatic" to some extent, it still requires both human input and human knowledge or experience, and thus is not deemed to be fully automatic. The goal of intelligent window selection is to automatically select windows based on a learnt engine that is built upon a huge number of existing windows generated through the adjoint tomography project. We have formulated the automatic window selection problem as a classification problem. All possible misfit calculation windows are classified as either usable or unusable. Given a large number of windows with a known selection mode (select or not select), we train a neural network to predict the selection mode of an arbitrary input window. Currently, the five features we extract from the windows are its cross-correlation value, cross-correlation time lag, amplitude ratio between observed and synthetic data, window length, and minimum STA/LTA value. More features can be included in the future. We use these features to characterize each window for training a multilayer perceptron neural network (MPNN). Training the MPNN is equivalent to solve a non-linear optimization problem. We use backward propagation to derive the gradient of the loss function with respect to the weighting matrices and bias vectors and use the mini-batch stochastic gradient method to iteratively optimize the MPNN. Numerical tests show that with a careful selection of the training data and a sufficient amount of training data, we are able to train a robust neural network that is capable of detecting the waveforms in an arbitrary earthquake data with negligible detection error

Assessing Thermal Comfort Due to a Ventilated Double Window

NASA Astrophysics Data System (ADS)

Carlos, Jorge S.; Corvacho, Helena

2017-10-01

Building design and its components are the result of a complex process, which should provide pleasant conditions to its inhabitants. Therefore, indoor acceptable comfort is influenced by the architectural design. ISO and ASHRAE standards define thermal comfort as the condition of mind that expresses satisfaction with the thermal environment. The energy demand for heating, beside the building’s physical properties, also depend on human behaviour, like opening or closing windows. Generally, windows are the weakest façade element concerning to thermal performance. A lower thermal resistance allows higher thermal conduction through it. When a window is very hot or cold, and the occupant is very close to it, it may result in thermal discomfort. The functionality of a ventilated double window introduces new physical considerations to a traditional window. In consequence, it is necessary to study the local effect on human comfort in function of the boundary conditions. Wind, solar availability, air temperature and therefore heating and indoor air quality conditions will affect the relationship between this passive system and the indoor environment. In the present paper, the influence of thermal performance and ventilation on human comfort resulting from the construction and geometry solutions is shown, helping to choose the best solution. The presented approach shows that in order to save energy it is possible to reduce the air changes of a room to the minimum, without compromising air quality, enhancing simultaneously local thermal performance and comfort. The results of the study on the effect of two parallel windows with a ventilated channel in the same fenestration on comfort conditions for several different room dimensions, are also presented. As the room dimensions’ rate changes so does the window to floor rate; therefore, under the same climatic conditions and same construction solution, different results are obtained.

Minimal Window Duration for Accurate HRV Recording in Athletes.

PubMed

Bourdillon, Nicolas; Schmitt, Laurent; Yazdani, Sasan; Vesin, Jean-Marc; Millet, Grégoire P

2017-01-01

Heart rate variability (HRV) is non-invasive and commonly used for monitoring responses to training loads, fitness, or overreaching in athletes. Yet, the recording duration for a series of RR-intervals varies from 1 to 15 min in the literature. The aim of the present work was to assess the minimum record duration to obtain reliable HRV results. RR-intervals from 159 orthostatic tests (7 min supine, SU, followed by 6 min standing, ST) were analyzed. Reference windows were 4 min in SU (min 3-7) and 4 min in ST (min 9-13). Those windows were subsequently divided and the analyses were repeated on eight different fractioned windows: the first min (0-1), the second min (1-2), the third min (2-3), the fourth min (3-4), the first 2 min (0-2), the last 2 min (2-4), the first 3 min (0-3), and the last 3 min (1-4). Correlation and Bland & Altman statistical analyses were systematically performed. The analysis window could be shortened to 0-2 instead of 0-4 for RMSSD only, whereas the 4-min window was necessary for LF and total power. Since there is a need for 1 min of baseline to obtain a steady signal prior the analysis window, we conclude that studies relying on RMSSD may shorten the windows to 3 min (= 1+2) in SU or seated position only and to 6 min (= 1+2 min SU plus 1+2 min ST) if there is an orthostatic test. Studies relying on time- and frequency-domain parameters need a minimum of 5 min (= 1+4) min SU or seated position only but require 10 min (= 1+4 min SU plus 1+4 min ST) for the orthostatic test.

Minimal Window Duration for Accurate HRV Recording in Athletes

PubMed Central

Bourdillon, Nicolas; Schmitt, Laurent; Yazdani, Sasan; Vesin, Jean-Marc; Millet, Grégoire P.

2017-01-01

Heart rate variability (HRV) is non-invasive and commonly used for monitoring responses to training loads, fitness, or overreaching in athletes. Yet, the recording duration for a series of RR-intervals varies from 1 to 15 min in the literature. The aim of the present work was to assess the minimum record duration to obtain reliable HRV results. RR-intervals from 159 orthostatic tests (7 min supine, SU, followed by 6 min standing, ST) were analyzed. Reference windows were 4 min in SU (min 3–7) and 4 min in ST (min 9–13). Those windows were subsequently divided and the analyses were repeated on eight different fractioned windows: the first min (0–1), the second min (1–2), the third min (2–3), the fourth min (3–4), the first 2 min (0–2), the last 2 min (2–4), the first 3 min (0–3), and the last 3 min (1–4). Correlation and Bland & Altman statistical analyses were systematically performed. The analysis window could be shortened to 0–2 instead of 0–4 for RMSSD only, whereas the 4-min window was necessary for LF and total power. Since there is a need for 1 min of baseline to obtain a steady signal prior the analysis window, we conclude that studies relying on RMSSD may shorten the windows to 3 min (= 1+2) in SU or seated position only and to 6 min (= 1+2 min SU plus 1+2 min ST) if there is an orthostatic test. Studies relying on time- and frequency-domain parameters need a minimum of 5 min (= 1+4) min SU or seated position only but require 10 min (= 1+4 min SU plus 1+4 min ST) for the orthostatic test. PMID:28848382

New machining method of high precision infrared window part

NASA Astrophysics Data System (ADS)

Yang, Haicheng; Su, Ying; Xu, Zengqi; Guo, Rui; Li, Wenting; Zhang, Feng; Liu, Xuanmin

2016-10-01

Most of the spherical shell of the photoelectric multifunctional instrument was designed as multi optical channel mode to adapt to the different band of the sensor, there were mainly TV, laser and infrared channels. Without affecting the optical diameter, wind resistance and pneumatic performance of the optical system, the overall layout of the spherical shell was optimized to save space and reduce weight. Most of the shape of the optical windows were special-shaped, each optical window directly participated in the high resolution imaging of the corresponding sensor system, and the optical axis parallelism of each sensor needed to meet the accuracy requirement of 0.05mrad.Therefore precision machining of optical window parts quality will directly affect the photoelectric system's pointing accuracy and interchangeability. Processing and testing of the TV and laser window had been very mature, while because of the special nature of the material, transparent and high refractive rate, infrared window parts had the problems of imaging quality and the control of the minimum focal length and second level parallel in the processing. Based on years of practical experience, this paper was focused on how to control the shape and parallel difference precision of infrared window parts in the processing. Single pass rate was increased from 40% to more than 95%, the processing efficiency was significantly enhanced, an effective solution to the bottleneck problem in the actual processing, which effectively solve the bottlenecks in research and production.

16 CFR 455.2 - Consumer sales-window form.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 16 Commercial Practices 1 2011-01-01 2011-01-01 false Consumer sales-window form. 455.2 Section... REGULATION RULE § 455.2 Consumer sales—window form. (a) General duty. Before you offer a used vehicle for sale to a consumer, you must prepare, fill in as applicable and display on that vehicle a “Buyers Guide...

Measure Guideline. Wood Window Repair, Rehabilitation, and Replacement

DOE Office of Scientific and Technical Information (OSTI.GOV)

Baker, P.; Eng, P.

2012-12-01

This measure guideline provides information and guidance on rehabilitating, retrofitting, and replacing existing window assemblies in residential construction. The intent is to provide information regarding means and methods to improve the energy and comfort performance of existing wood window assemblies in a way that takes into consideration component durability, in-service operation, and long term performance of the strategies.

Fused silica windows for solar receiver applications

NASA Astrophysics Data System (ADS)

Hertel, Johannes; Uhlig, Ralf; Söhn, Matthias; Schenk, Christian; Helsch, Gundula; Bornhöft, Hansjörg

2016-05-01

A comprehensive study of optical and mechanical properties of quartz glass (fused silica) with regard to application in high temperature solar receivers is presented. The dependence of rupture strength on different surface conditions as well as high temperature is analyzed, focussing particularly on damage by devitrification and sandblasting. The influence of typical types of contamination in combination with thermal cycling on the optical properties of fused silica is determined. Cleaning methods are compared regarding effectiveness on contamination-induced degradation for samples with and without antireflective coating. The FEM-aided design of different types of receiver windows and their support structure is presented. A large-scale production process has been developed for producing fused silica dome shaped windows (pressurized window) up to a diameter of 816 mm. Prototypes were successfully pressure-tested in a test bench and certified according to the European Pressure Vessel Directive.

[Models and Foundations of Developmental Education.

ERIC Educational Resources Information Center

Boylan, Hunter R., Ed.; Kerstiens, Gene, Ed.

1988-01-01

These five issues of "Research in Developmental Education," examine the theoretical models and foundations of developmental education. Included are the following: (1) "Theoretical Foundations of Developmental Education," by Hunter R. Boylan, which examines the behaviorist, humanist, and developmental theories underpinning developmental education;…

Optical performance of segmented aperture windows for solar tower receivers

NASA Astrophysics Data System (ADS)

Buck, Reiner

2017-06-01

Segmented quartz windows are a concept to build larger windows for receivers that require a closed aperture. Reflection losses are a significant loss factor for such solar receivers. Without any additional measures, the reflection loss can reach about 12%. One important measure to improve transmission is the application of anti-reflective coatings, which is beneficial in any case. Another option is modifying the window geometry, especially the edge surfaces of the glass segments. A certain fraction of the reflection losses are caused by a light-guide effect in the glass body, for rays entering through the front surface. Changing the cut surfaces in a way reducing the light-guide effect can significantly improve transmission of a segmented window. Several possible configurations are evaluated and discussed. The results of ray-tracing simulations verify the improvement. The final selection of the window configuration depends on the optical properties and on mechanical strength, manufacturing and cost considerations. This has to be evaluated for any specific receiver design.

Window Design Strategies to Conserve Energy. NBS Building Science Series 104.

ERIC Educational Resources Information Center

Hastings, S. Robert; Crenshaw, Richard W.

A multitude of design strategies are available to achieve energy-efficient windows. Opportunities for improving window performance fall into six groups: site, exterior appendages, frame, glazing, interior accessories, and building interior. Design strategies within these groups can improve one or more of the six energy functions of windows: solar…

Optimal Window and Lattice in Gabor Transform. Application to Audio Analysis.

PubMed

Lachambre, Helene; Ricaud, Benjamin; Stempfel, Guillaume; Torrésani, Bruno; Wiesmeyr, Christoph; Onchis-Moaca, Darian

2015-01-01

This article deals with the use of optimal lattice and optimal window in Discrete Gabor Transform computation. In the case of a generalized Gaussian window, extending earlier contributions, we introduce an additional local window adaptation technique for non-stationary signals. We illustrate our approach and the earlier one by addressing three time-frequency analysis problems to show the improvements achieved by the use of optimal lattice and window: close frequencies distinction, frequency estimation and SNR estimation. The results are presented, when possible, with real world audio signals.

Hydrofluoric acid-resistant composite window and method for its fabrication

DOEpatents

Ostenak, C.A.; Mackay, H.A.

1985-07-18

A hydrofluoric acid-resistant composite window and method for its fabrication are disclosed. The composite window comprises a window having first and second sides. The first side is oriented towards an environment containing hydrofluoric acid. An adhesive is applied to the first side. A layer of transparent hydrofluoric acid-resistant material, such as Mylar, is applied to the adhesive and completely covers the first side. The adhesive is then cured.

Demonstration Program for Low-Cost, High-Energy-Saving Dynamic Windows

DTIC Science & Technology

2014-09-01

Design The scope of this project was to demonstrate the impact of dynamic windows via energy savings and HVAC peak-load reduction; to validate the...temperature and glare. While the installed dynamic window system does not directly control the HVAC or lighting of the facility, those systems are designed ...optimize energy efficiency and HVAC load management. The conversion to inoperable windows caused an unforeseen reluctance to accept the design and

Hydrofluoric acid-resistant composite window and method for its fabrication

DOEpatents

Ostenak, Carl A.; Mackay, Harold A.

1987-01-01

A hydrofluoric acid-resistant composite window and method for its fabrication are disclosed. The composite window comprises a window having first and second sides. The first side is oriented towards an environment containing hydrofluoric acid. An adhesive is applied to the first side. A layer of transparent hydrofluoric acid-resistant material, such as Mylar, is applied to the adhesive and completely covers the first side. The adhesive is then cured.

Laser-induced damage and fracture in fused silica vacuum windows

NASA Astrophysics Data System (ADS)

Campbell, John H.; Hurst, Patricia A.; Heggins, Dwight D.; Steele, William A.; Bumpas, Stanley E.

1997-05-01

Laser induced damage, that initiates catastrophic fracture, has been observed in large, fused silica lenses that also serve as vacuum barriers in high-fluence positions on the Nova and Beamlet lasers. In nearly all cases damage occurs on the vacuum side of the lens. The damage can lead to catastrophic crack growth if the flaw size exceeds the critical flaw size for SiO2. If the elastic stored energy in the lens in high enough, the lens will fracture into many pieces resulting in an implosion. The consequences of such an implosion can be severe, particularly for large vacuum systems. Three parameters control the degree of fracture in the vacuum barrier window: (1) the elastic stored energy, (2) the ratio of the window thickness to flaw depth and (3) secondary crack propagation. Fracture experiments have ben carried our on 15-cm diameter fused silica windows that contain surface flaws caused by laser damage. The results of these experiments, combined with data from window failures on Beamlet and Nova have been sued to develop design criteria for a 'fail-safe' lens. Specifically the window must be made thick enough such that the peak tensile stress is less than 500 psi and the corresponding ratio of the thickness to critical flaw size is less than 6. Under these conditions a properly mounted window, upon failure, will break into only tow pieces and will not implode. One caveat to these design criteria is that the air leak through the window before secondary crack growth occurs. Finite element stress calculations of a window before and immediately following fracture into two pieces show that the elastic stored energy is redistributed if the fragments 'lock' in place and thereby bridge the opening. In such cases, the peak stresses at the flaw site can increase leading to further crack growth.

Microwave window breakdown experiments and simulations on the UM/L-3 relativistic magnetron

NASA Astrophysics Data System (ADS)

Hoff, B. W.; Mardahl, P. J.; Gilgenbach, R. M.; Haworth, M. D.; French, D. M.; Lau, Y. Y.; Franzi, M.

2009-09-01

Experiments have been performed on the UM/L-3 (6-vane, L-band) relativistic magnetron to test a new microwave window configuration designed to limit vacuum side breakdown. In the baseline case, acrylic microwave windows were mounted between three of the waveguide coupling cavities in the anode block vacuum housing and the output waveguides. Each of the six 3 cm deep coupling cavities is separated from its corresponding anode cavity by a 1.75 cm wide aperture. In the baseline case, vacuum side window breakdown was observed to initiate at single waveguide output powers close to 20 MW. In the new window configuration, three Air Force Research Laboratory-designed, vacuum-rated directional coupler waveguide segments were mounted between the coupling cavities and the microwave windows. The inclusion of the vacuum side power couplers moved the microwave windows an additional 30 cm away from the anode apertures. Additionally, the Lucite microwave windows were replaced with polycarbonate windows and the microwave window mounts were redesigned to better maintain waveguide continuity in the region around the microwave windows. No vacuum side window breakdown was observed in the new window configuration at single waveguide output powers of 120+MW (a factor of 3 increase in measured microwave pulse duration and factor of 3 increase in measured peak power over the baseline case). Simulations were performed to investigate likely causes for the window breakdown in the original configuration. Results from these simulations have shown that in the original configuration, at typical operating voltage and magnetic field ranges, electrons emitted from the anode block microwave apertures strike the windows with a mean kinetic energy of 33 keV with a standard deviation of 14 keV. Calculations performed using electron impact angle and energy data predict a first generation secondary electron yield of 65% of the primary electron population. The effects of the primary aperture electron

Non-valvular main pulmonary artery vegetation associated with aortopulmonary window.

PubMed

Unal, M; Tuncer, C; Serçe, K; Bostan, M; Gökçe, M; Erem, C

1995-01-01

We present a 32-year-old female with aortopulmonary window and vegetation of non-valvular main pulmonary artery. The aortopulmonary window is a rare congenital disease in which the aorta and pulmonary arteries are communicated by a defect of variable diameter. The pulmonic valve is the least commonly involved valve in bacterial endocarditis, but there is no vegetation of non-valvular main pulmonary artery in the literature. Colour duplex sonography showed an aortopulmonary window with aortic regurgitation. Magnetic resonance (MR) imaging demonstrating the vegetation on the wall of main pulmonary artery, is an useful and complementary method, and can be used for demonstration of congenital and acquired cardiovascular pathologies including aortopulmonary window and subpulmonic or suprapulmonic vegetations.

The Zebrafish Models to Explore Genetic and Epigenetic Impacts on Evolutionary Developmental Origins of Aging

PubMed Central

Kishi, Shuji

2014-01-01

Can we reset, reprogram, rejuvenate or reverse the organismal aging process? Certain genetic manipulations could at least reset and reprogram epigenetic dynamics beyond phenotypic plasticity and elasticity in cells, which can be further manipulated into organisms. However, in a whole complex aging organism, how can we rejuvenate intrinsic resources and infrastructures in an intact/noninvasive manner? The incidence of diseases increases exponentially with age, accompanied by progressive deteriorations of physiological functions in organisms. Aging-associated diseases are sporadic but essentially inevitable complications arising from senescence. Senescence is often considered the antithesis of early development, but yet there may be factors and mechanisms in common between these two phenomena to rejuvenate over the dynamic process of aging. The association between early development and late-onset disease with advancing age is thought to come from a consequence of developmental plasticity, the phenomenon by which one genotype can give rise to a range of physiologically and/or morphologically adaptive states based on diverse epigenotypes, in response to intrinsic or extrinsic environmental cues and genetic perturbations. We hypothesized that the future aging process can be predictive based on adaptivity during the early developmental period. Modulating the thresholds and windows of plasticity and its robustness by molecular genetic and chemical epigenetic approaches, we have successfully conducted experiments to isolate zebrafish mutants expressing apparently altered senescence phenotypes during their embryonic and/or larval stages (“embryonic/larval senescence”). Subsequently, at least some of these mutant animals were found to show shortened lifespan, while some others would be expected to live longer in adulthoods. We anticipate that previously uncharacterized developmental genes may mediate the aging process and play a pivotal role in senescence. On the other