Sample records for narrow substrate spectrum

  1. CHARACTERIZATION OF A NARROW SPECTRUM ANTIMICROBIAL THAT EXHIBITS SPECIFIC ACTIVITY AGAINST UROPATHOGENIC BACTERIA

    DTIC Science & Technology

    2017-08-28

    NARROW-SPECTRUM ANTIMICROBIAL THAT EXHIBITS SPECIFIC ACTIVITY AGAINST UROPATHOGENIC BACTERIA by Caitlin M. Barrows Courtney M. Cowell Jennifer...From - To) October 2015 – September 2016 4. TITLE AND SUBTITLE CHARACTERIZATION OF A NARROW-SPECTRUM ANTIMICROBIAL THAT EXHIBITS SPECIFIC ACTIVITY ...objective of the work described in this report is to identify a narrow-spectrum antimicrobial that exhibits targeted activity against uropathogenic

  2. Extended Versus Narrow-spectrum Antibiotics in the Management of Uncomplicated Appendicitis in Children: A Propensity-matched Comparative Effectiveness Study.

    PubMed

    Cameron, Danielle B; Melvin, Patrice; Graham, Dionne A; Glass, Charity C; Serres, Stephanie K; Kronman, Matthew P; Saito, Jacqueline M; Rangel, Shawn J

    2018-07-01

    The aim of this study was to compare the effectiveness of extended versus narrow spectrum antibiotics in preventing surgical site infections (SSIs) and hospital revisits in children with uncomplicated appendicitis. There is a paucity of high-quality evidence in the pediatric literature comparing the effectiveness of extended versus narrow-spectrum antibiotics in the prevention of SSIs associated with uncomplicated appendicitis. Clinical data from the ACS NSQIP-Pediatric Appendectomy Pilot Project were merged with antibiotic utilization data from the Pediatric Health Information System database for patients undergoing appendectomy for uncomplicated appendicitis at 17 hospitals from January 1, 2013 to June 30, 2015. Patients who received piperacillin/tazobactam (extended spectrum) were compared with those who received either cefoxitin or ceftriaxone with metronidazole (narrow spectrum) after propensity matching on demographic and severity characteristics. Study outcomes were 30-day SSI and hospital revisit rates. Of the 1389 patients included, 39.1% received piperacillin/tazobactam (range by hospital: 0% to 100%), and the remainder received narrow-spectrum agents. No differences in demographics or severity characteristics were found between groups following matching. In the matched analysis, the rates of SSI were similar between groups [extended spectrum: 2.4% vs narrow spectrum 1.8% (odds ratio, OR: 1.05, 95% confidence interval, 95% CI 0.34-3.26)], as was the rate of revisits [extended spectrum: 7.9% vs narrow spectrum 5.1% (OR: 1.46, 95% CI 0.75-2.87)]. Use of extended-spectrum antibiotics was not associated with lower rates of SSI or hospital revisits when compared with narrow-spectrum antibiotics in children with uncomplicated appendicitis. Our results challenge the routine use of extended-spectrum antibiotics observed at many hospitals, particularly given the increasing incidence of antibiotic-resistant organisms.

  3. Broad- versus Narrow-Spectrum Oral Antibiotic Transition and Outcomes in Health Care-associated Pneumonia.

    PubMed

    Buckel, Whitney R; Stenehjem, Edward; Sorensen, Jeff; Dean, Nathan; Webb, Brandon

    2017-02-01

    Guidelines recommend a switch from intravenous to oral antibiotics once patients who are hospitalized with pneumonia achieve clinical stability. However, little evidence guides the selection of an oral antibiotic for patients with health care-associated pneumonia, especially where no microbiological diagnosis is made. To compare outcomes between patients who were transitioned to broad- versus narrow-spectrum oral antibiotics after initially receiving broad-spectrum intravenous antibiotic coverage. We performed a secondary analysis of an existing database of adults with community-onset pneumonia admitted to seven Utah hospitals. We identified 220 inpatients with microbiology-negative health care-associated pneumonia from 2010 to 2012. After excluding inpatient deaths and treatment failures, 173 patients remained in which broad-spectrum intravenous antibiotics were transitioned to an oral regimen. We classified oral regimens as broad-spectrum (fluoroquinolone) versus narrow-spectrum (usually a β-lactam). We compared demographic and clinical characteristics between groups. Using a multivariable regression model, we adjusted outcomes by severity (electronically calculated CURB-65), comorbidity (Charlson Index), time to clinical stability, and length of intravenous therapy. Age, severity, comorbidity, length of intravenous therapy, and clinical response were similar between the two groups. Observed 30-day readmission (11.9 vs. 21.4%; P = 0.26) and 30-day all-cause mortality (2.3 vs. 5.3%; P = 0.68) were also similar between the narrow and broad oral antibiotic groups. In multivariable analysis, we found no statistically significant differences for adjusted odds of 30-day readmission (adjusted odds ratio, 0.56; 95% confidence interval, 0.06-5.2; P = 0.61) or 30-day all-cause mortality (adjusted odds ratio, 0.55; 95% confidence interval, 0.19-1.6; P = 0.26) between narrow and broad oral antibiotic groups. On the basis of analysis of a limited number of patients

  4. Recipient luminophoric mediums having narrow spectrum luminescent materials and related semiconductor light emitting devices and methods

    DOEpatents

    LeToquin, Ronan P; Tong, Tao; Glass, Robert C

    2014-12-30

    Light emitting devices include a light emitting diode ("LED") and a recipient luminophoric medium that is configured to down-convert at least some of the light emitted by the LED. In some embodiments, the recipient luminophoric medium includes a first broad-spectrum luminescent material and a narrow-spectrum luminescent material. The broad-spectrum luminescent material may down-convert radiation emitted by the LED to radiation having a peak wavelength in the red color range. The narrow-spectrum luminescent material may also down-convert radiation emitted by the LED into the cyan, green or red color range.

  5. Association of Broad- vs Narrow-Spectrum Antibiotics With Treatment Failure, Adverse Events, and Quality of Life in Children With Acute Respiratory Tract Infections.

    PubMed

    Gerber, Jeffrey S; Ross, Rachael K; Bryan, Matthew; Localio, A Russell; Szymczak, Julia E; Wasserman, Richard; Barkman, Darlene; Odeniyi, Folasade; Conaboy, Kathryn; Bell, Louis; Zaoutis, Theoklis E; Fiks, Alexander G

    2017-12-19

    Acute respiratory tract infections account for the majority of antibiotic exposure in children, and broad-spectrum antibiotic prescribing for acute respiratory tract infections is increasing. It is not clear whether broad-spectrum treatment is associated with improved outcomes compared with narrow-spectrum treatment. To compare the effectiveness of broad-spectrum and narrow-spectrum antibiotic treatment for acute respiratory tract infections in children. A retrospective cohort study assessing clinical outcomes and a prospective cohort study assessing patient-centered outcomes of children between the ages of 6 months and 12 years diagnosed with an acute respiratory tract infection and prescribed an oral antibiotic between January 2015 and April 2016 in a network of 31 pediatric primary care practices in Pennsylvania and New Jersey. Stratified and propensity score-matched analyses to account for confounding by clinician and by patient-level characteristics, respectively, were implemented for both cohorts. Broad-spectrum antibiotics vs narrow-spectrum antibiotics. In the retrospective cohort, the primary outcomes were treatment failure and adverse events 14 days after diagnosis. In the prospective cohort, the primary outcomes were quality of life, other patient-centered outcomes, and patient-reported adverse events. Of 30 159 children in the retrospective cohort (19 179 with acute otitis media; 6746, group A streptococcal pharyngitis; and 4234, acute sinusitis), 4307 (14%) were prescribed broad-spectrum antibiotics including amoxicillin-clavulanate, cephalosporins, and macrolides. Broad-spectrum treatment was not associated with a lower rate of treatment failure (3.4% for broad-spectrum antibiotics vs 3.1% for narrow-spectrum antibiotics; risk difference for full matched analysis, 0.3% [95% CI, -0.4% to 0.9%]). Of 2472 children enrolled in the prospective cohort (1100 with acute otitis media; 705, group A streptococcal pharyngitis; and 667, acute sinusitis), 868

  6. Enhancing the visibility of injuries with narrow-banded beams of light within the visible light spectrum.

    PubMed

    Limmen, Roxane M; Ceelen, Manon; Reijnders, Udo J L; Joris Stomp, S; de Keijzer, Koos C; Das, Kees

    2013-03-01

    The use of narrow-banded visible light sources in improving the visibility of injuries has been hardly investigated, and studies examining the extent of this improvement are lacking. In this study, narrow-banded beams of light within the visible light spectrum were used to explore their ability in improving the visibility of external injuries. The beams of light were induced by four crime-lites(®) providing narrow-banded beams of light between 400 and 550 nm. The visibility of the injuries was assessed through specific long-pass filters supplied with the set of crime-lites(®) . Forty-three percent of the examined injuries improved in visibility by using the narrow-banded visible light. In addition, injuries were visualized that were not visible or just barely visible to the naked eye. The improvements in visibility were particularly marked with the use of crime-lites(®) "violet" and "blue" covering the spectrum between 400-430 and 430-470 nm. The simple noninvasive method showed a great potential contribution in injury examination. © 2012 American Academy of Forensic Sciences.

  7. Direct observation of a Γ -X energy spectrum transition in narrow AlAs quantum wells

    NASA Astrophysics Data System (ADS)

    Khisameeva, A. R.; Shchepetilnikov, A. V.; Muravev, V. M.; Gubarev, S. I.; Frolov, D. D.; Nefyodov, Yu. A.; Kukushkin, I. V.; Reichl, C.; Tiemann, L.; Dietsche, W.; Wegscheider, W.

    2018-03-01

    Spectra of magnetoplasma excitations have been investigated in two-dimensional electron systems in AlAs quantum wells (QWs) of different widths. The magnetoplasma spectrum has been found to change profoundly when the quantum well width becomes thinner than 5.5 nm, indicating a drastic change in the conduction electron energy spectrum. The transformation can be interpreted in terms of transition from the in-plane strongly anisotropic Xx-Xy valley occupation to the out-of-plane isotropic Xz valley in the QW plane. Strong enhancement of the cyclotron effective mass over the band value in narrow AlAs QWs is reported.

  8. Electrochemical Synthesis of Bismuth Particles: Tuning Particle Shape through Substrate Type within a Narrow Potential Window

    PubMed Central

    Bilican, Doga; Fornell, Jordina; Sort, Jordi; Pellicer, Eva

    2017-01-01

    Bismuth (Bi) electrodeposition was studied on Si/Ti/Au, FTO-, and ITO-coated glasses from acidic nitrate solutions with and without gluconate within a narrow potential window (ΔE = 80 mV). This potential range was sufficient to observe a change in particle shape, from polyhedrons (including hexagons) to dendrites, the trend being slightly different depending on substrate activity. In all cases, though, the formation of dendrites was favoured as the applied potential was made more negative. Bi particles were more uniformly distributed over the substrate when sodium gluconate was added to the electrolyte. X-ray diffraction analyses of dendrites grown at −0.28 V indicated that they exhibit the rhombohedral phase of Bi and are predominantly oriented along the (003) plane. This orientation is exacerbated at the lowest applied potential (−0.20 V vs. Ag|AgCl) on glass/ITO substrate, for which completed and truncated hexagons are observed from the top view scanning electron microscopy images. PMID:28772402

  9. The Neural Substrates of Cognitive Control Deficits in Autism Spectrum Disorders

    ERIC Educational Resources Information Center

    Solomon, Marjorie; Ozonoff, Sally J.; Ursu, Stefan; Ravizza, Susan; Cummings, Neil; Ly, Stanford; Carter, Cameron S.

    2009-01-01

    Executive function deficits are among the most frequently reported symptoms of autism spectrum disorders (ASDs), however, there have been few functional magnetic resonance imaging (fMRI) studies that investigate the neural substrates of executive function deficits in ASDs, and only one in adolescents. The current study examined cognitive…

  10. Chromosome-encoded narrow-spectrum Ambler class A beta-lactamase GIL-1 from Citrobacter gillenii.

    PubMed

    Naas, Thierry; Aubert, Daniel; Ozcan, Ayla; Nordmann, Patrice

    2007-04-01

    A novel beta-lactamase gene was cloned from the whole-cell DNA of an enterobacterial Citrobacter gillenii reference strain that displayed a weak narrow-spectrum beta-lactam-resistant phenotype and was expressed in Escherichia coli. It encoded a clavulanic acid-inhibited Ambler class A beta-lactamase, GIL-1, with a pI value of 7.5 and a molecular mass of ca. 29 kDa. GIL-1 had the highest percent amino acid sequence identity with TEM-1 and SHV-1, 77%, and 67%, respectively, and only 46%, 31%, and 32% amino acid sequence identity with CKO-1 (C. koseri), CdiA1 (C. diversus), and SED-1 (C. sedlaki), respectively. The substrate profile of the purified GIL-1 was similar to that of beta-lactamases TEM-1 and SHV-1. The blaGIL-1 gene was chromosomally located, as revealed by I-CeuI experiments, and was constitutively expressed at a low level in C. gillenii. No gene homologous to the regulatory ampR genes of chromosomal class C beta-lactamases was found upstream of the blaGIL-1 gene, which fits the noninducibility of beta-lactamase expression in C. gillenii. Rapid amplification of DNA 5' ends analysis of the promoter region revealed putative promoter sequences that diverge from what has been identified as the consensus sequence in E. coli. The blaGIL-1 gene was part of a 5.5-kb DNA fragment bracketed by a 9-bp duplication and inserted between the d-lactate dehydrogenase gene and the ydbH genes; this DNA fragment was absent in other Citrobacter species. This work further illustrates the heterogeneity of beta-lactamases in Citrobacter spp., which may indicate that the variability of Citrobacter species is greater than expected.

  11. Discovery of a narrow line quasar

    NASA Technical Reports Server (NTRS)

    Stocke, J.; Liebert, J.; Maccacaro, T.; Griffiths, R. E.; Steiner, J. E.

    1982-01-01

    A stellar object is reported which, while having X-ray and optical luminosities typical of quasars, has narrow permitted and forbidden emission lines over the observed spectral range. The narrow-line spectrum is high-excitation, the Balmer lines seem to be recombinational, and a redder optical spectrum than that of most quasars is exhibited, despite detection as a weak radio source. The object does not conform to the relationships between H-beta parameters and X-ray flux previously claimed for a large sample of the active galactic nuclei. Because reddish quasars with narrow lines, such as the object identified, may not be found by the standard techniques for the discovery of quasars, the object may be a prototype of a new class of quasars analogous to high-luminosity Seyfert type 2 galaxies. It is suggested that these objects cannot comprise more than 10% of all quasars.

  12. Effect of broad- and narrow-spectrum antimicrobials on Clostridium difficile and microbial diversity in a model of the distal colon

    PubMed Central

    Rea, Mary C.; Dobson, Alleson; O'Sullivan, Orla; Crispie, Fiona; Fouhy, Fiona; Cotter, Paul D.; Shanahan, Fergus; Kiely, Barry; Hill, Colin; Ross, R. Paul

    2011-01-01

    Vancomycin, metronidazole, and the bacteriocin lacticin 3147 are active against a wide range of bacterial species, including Clostridium difficile. We demonstrate that, in a human distal colon model, the addition of each of the three antimicrobials resulted in a significant decrease in numbers of C. difficile. However, their therapeutic use in the gastrointestinal tract may be compromised by their broad spectrum of activity, which would be expected to significantly impact on other members of the human gut microbiota. We used high-throughput pyrosequencing to compare the effect of each antimicrobial on the composition of the microbiota. All three treatments resulted in a decrease in the proportion of sequences assigned to the phyla Firmicutes and Bacteroidetes, with a corresponding increase in those assigned to members of the Proteobacteria. One possible means of avoiding such “collateral damage” would involve the application of a narrow-spectrum antimicrobial with specific anti-C. difficile activity. We tested this hypothesis using thuricin CD, a narrow-spectrum bacteriocin produced by Bacillus thuringiensis, which is active against C. difficile. The results demonstrated that this bacteriocin was equally effective at killing C. difficile in the distal colon model but had no significant impact on the composition of the microbiota. This offers the possibility of developing a targeted approach to eliminating C. difficile in the colon, without collateral damage. PMID:20616009

  13. A novel method for detecting airway narrowing using breath sound spectrum analysis in children.

    PubMed

    Tabata, Hideyuki; Hirayama, Mariko; Enseki, Mayumi; Nukaga, Mariko; Hirai, Kota; Furuya, Hiroyuki; Mochizuki, Hiroyuki

    2016-01-01

    Using a breath sound analyzer, we investigated new clinical parameters that are rarely affected by airflow in young children. A total of 65 children with asthma participated in this study (mean age 9.6 years). In Study 1, the intra- and inter-observer variability was measured. Common breath sound parameters, frequency at 99%, 75%, and 50% of the maximum frequency (F99, F75, and F50) and the highest frequency of inspiratory breath sounds were calculated. In addition, new parameters obtained using the ratio of sound spectra parameters, i.e., the spectrum curve indexes including the ratio of the third and fourth area to the total area and the ratio of power and frequency at F75 and F50, were calculated. In Study 2, 51 children underwent breath sound analyses. In Study 3, breath sounds were studied before and after methacholine inhalation. In Study 1, the data showed good inter- and intra-observer reliability. In Study 2, there were significant relationships between the airflow rate, age, height, and spirometric and common breath sound parameters. However, there were no significant relationships between the airflow rate and the spectrum curve indexes. Moreover, the spectrum curve indexes showed no relationships with age, height, or spirometric parameters. In Study 3, all parameters significantly changed after methacholine inhalation. Some spectrum curve indexes are not significantly affected by the airflow rate at the mouth, although they successfully indicate airway narrowing. These parameters may play a role in the assessment of bronchoconstriction in children. Copyright © 2015 The Japanese Respiratory Society. Published by Elsevier B.V. All rights reserved.

  14. Quantitative Raman spectrum and reliable thickness identification for atomic layers on insulating substrates.

    PubMed

    Li, Song-Lin; Miyazaki, Hisao; Song, Haisheng; Kuramochi, Hiromi; Nakaharai, Shu; Tsukagoshi, Kazuhito

    2012-08-28

    We demonstrate the possibility in quantifying the Raman intensities for both specimen and substrate layers in a common stacked experimental configuration and, consequently, propose a general and rapid thickness identification technique for atomic-scale layers on dielectric substrates. Unprecedentedly wide-range Raman data for atomically flat MoS(2) flakes are collected to compare with theoretical models. We reveal that all intensity features can be accurately captured when including optical interference effect. Surprisingly, we find that even freely suspended chalcogenide few-layer flakes have a stronger Raman response than that from the bulk phase. Importantly, despite the oscillating intensity of specimen spectrum versus thickness, the substrate weighted spectral intensity becomes monotonic. Combined with its sensitivity to specimen thickness, we suggest this quantity can be used to rapidly determine the accurate thickness for atomic layers.

  15. Improved spatial resolution and lower-dose pediatric CT imaging: a feasibility study to evaluate narrowing the X-ray photon energy spectrum.

    PubMed

    Benz, Mark G; Benz, Matthew W; Birnbaum, Steven B; Chason, Eric; Sheldon, Brian W; McGuire, Dale

    2014-08-01

    This feasibility study has shown that improved spatial resolution and reduced radiation dose can be achieved in pediatric CT by narrowing the X-ray photon energy spectrum. This is done by placing a hafnium filter between the X-ray generator and a pediatric abdominal phantom. A CT system manufactured in 1999 that was in the process of being remanufactured was used as the platform for this study. This system had the advantage of easy access to the X-ray generator for modifications to change the X-ray photon energy spectrum; it also had the disadvantage of not employing the latest post-imaging noise reduction iterative reconstruction technology. Because we observed improvements after changing the X-ray photon energy spectrum, we recommend a future study combining this change with an optimized iterative reconstruction noise reduction technique.

  16. Samarium electrodeposited acetate and oxide thin films on stainless steel substrate characterized by XPS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Myhre, Kristian; Burns, Jonathan; Meyer, Harry

    Characterization of a samarium thin film deposited on a stainless steel substrate using molecular electrodeposition was carried out using a Thermo Scientific K-Alpha X-ray photoelectron spectrometer. We studied two types of samarium electrodeposition samples, one as-deposited and one heated to 700 °C in an air flow. Survey scans include peaks coming from the stainless steel substrate, such as Fe and Cr. An X-ray photoelectron spectroscopy (XPS) survey spectrum, Sm 3d, C 1s, and O 1s narrow scans are shown. It was determined that the heating process decomposed the deposited Sm acetate to Sm 2O 3 using XPS.

  17. Samarium electrodeposited acetate and oxide thin films on stainless steel substrate characterized by XPS

    DOE PAGES

    Myhre, Kristian; Burns, Jonathan; Meyer, Harry; ...

    2016-06-01

    Characterization of a samarium thin film deposited on a stainless steel substrate using molecular electrodeposition was carried out using a Thermo Scientific K-Alpha X-ray photoelectron spectrometer. We studied two types of samarium electrodeposition samples, one as-deposited and one heated to 700 °C in an air flow. Survey scans include peaks coming from the stainless steel substrate, such as Fe and Cr. An X-ray photoelectron spectroscopy (XPS) survey spectrum, Sm 3d, C 1s, and O 1s narrow scans are shown. It was determined that the heating process decomposed the deposited Sm acetate to Sm 2O 3 using XPS.

  18. Can They See It? The Functional Field of View Is Narrower in Individuals with Autism Spectrum Disorder.

    PubMed

    Song, Yongning; Hakoda, Yuji; Sanefuji, Wakako; Cheng, Chen

    2015-01-01

    Although social cognitive deficits have long been thought to underlie the characteristic and pervasive difficulties with social interaction observed in individuals with autism spectrum disorder (ASD), several recent behavioral and neuroimaging studies have indicated that visual perceptual impairments might also play a role. People with ASD show a robust bias towards detailed information at the expense of global information, although the mechanisms that underlie this phenomenon remain elusive. To address this issue, we investigated the functional field of view in a group of high-functioning children with autism (n = 13) and a paired non-ASD group (n = 13). Our results indicate that the ability to correctly detect and identify stimuli sharply decreases with greater eccentricity from the fovea in people with ASD. Accordingly, a probe analysis revealed that the functional field of view in the ASD group was only about 6.62° of retinal eccentricity, compared with 8.57° in typically developing children. Thus, children with ASD appear to have a narrower functional field of view. These results challenge the conventional hypothesis that the deficit in global processing in individuals with ASD is solely due to weak central coherence. Alternatively, our data suggest that a narrower functional field of view may also contribute to this bias.

  19. Photonic bandgap narrowing in conical hollow core Bragg fibers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ozturk, Fahri Emre; Yildirim, Adem; Kanik, Mehmet

    2014-08-18

    We report the photonic bandgap engineering of Bragg fibers by controlling the thickness profile of the fiber during the thermal drawing. Conical hollow core Bragg fibers were produced by thermal drawing under a rapidly alternating load, which was applied by introducing steep changes to the fiber drawing speed. In conventional cylindrical Bragg fibers, light is guided by omnidirectional reflections from interior dielectric mirrors with a single quarter wave stack period. In conical fibers, the diameter reduction introduced a gradient of the quarter wave stack period along the length of the fiber. Therefore, the light guided within the fiber encountered slightlymore » smaller dielectric layer thicknesses at each reflection, resulting in a progressive blueshift of the reflectance spectrum. As the reflectance spectrum shifts, longer wavelengths of the initial bandgap cease to be omnidirectionally reflected and exit through the cladding, which narrows the photonic bandgap. A narrow transmission bandwidth is particularly desirable in hollow waveguide mid-infrared sensing schemes, where broadband light is coupled to the fiber and the analyte vapor is introduced into the hollow core to measure infrared absorption. We carried out sensing simulations using the absorption spectrum of isopropyl alcohol vapor to demonstrate the importance of narrow bandgap fibers in chemical sensing applications.« less

  20. A narrow band pattern-matching model of vowel perception

    NASA Astrophysics Data System (ADS)

    Hillenbrand, James M.; Houde, Robert A.

    2003-02-01

    The purpose of this paper is to propose and evaluate a new model of vowel perception which assumes that vowel identity is recognized by a template-matching process involving the comparison of narrow band input spectra with a set of smoothed spectral-shape templates that are learned through ordinary exposure to speech. In the present simulation of this process, the input spectra are computed over a sufficiently long window to resolve individual harmonics of voiced speech. Prior to template creation and pattern matching, the narrow band spectra are amplitude equalized by a spectrum-level normalization process, and the information-bearing spectral peaks are enhanced by a ``flooring'' procedure that zeroes out spectral values below a threshold function consisting of a center-weighted running average of spectral amplitudes. Templates for each vowel category are created simply by averaging the narrow band spectra of like vowels spoken by a panel of talkers. In the present implementation, separate templates are used for men, women, and children. The pattern matching is implemented with a simple city-block distance measure given by the sum of the channel-by-channel differences between the narrow band input spectrum (level-equalized and floored) and each vowel template. Spectral movement is taken into account by computing the distance measure at several points throughout the course of the vowel. The input spectrum is assigned to the vowel template that results in the smallest difference accumulated over the sequence of spectral slices. The model was evaluated using a large database consisting of 12 vowels in /hVd/ context spoken by 45 men, 48 women, and 46 children. The narrow band model classified vowels in this database with a degree of accuracy (91.4%) approaching that of human listeners.

  1. Consequences of narrow cyclotron emission from Hercules X-1

    NASA Technical Reports Server (NTRS)

    Weaver, R. P.

    1978-01-01

    The implications of the recent observations of a narrow cyclotron line in the hard X-ray spectrum of Hercules X-1 are studied. A Monte Carlo code is used to simulate the X-ray transfer of an intrinsically narrow feature at approximately 56 keV through an opaque, cold magnetospheric shell. The results of this study indicate that if a narrow line can be emitted by the source region, then only about 10% of the photons remain in a narrow feature after scattering through the shell. The remaining photons are scattered into a broad feature (FWHM approximately 30 keV) that peaks near 20 keV. Thus, these calculations indicate that the intrinsic source luminosity of the cyclotron line is at least an order of magnitude greater than the observed luminosity.

  2. X-ray probe of GaN thin films grown on InGaN compliant substrates

    NASA Astrophysics Data System (ADS)

    Xu, Xiaoqing; Li, Yang; Liu, Jianming; Wei, Hongyuan; Liu, Xianglin; Yang, Shaoyan; Wang, Zhanguo; Wang, Huanhua

    2013-04-01

    GaN thin films grown on InGaN compliant substrates were characterized by several X-ray technologies: X-ray reciprocal space mapping (RSM), grazing incidence X-ray diffraction (GIXRD), and X-ray photoemission spectrum (XPS). Narrow Lorentz broadening and stress free state were observed for GaN grown on InGaN compliant substrate, while mosaic structure and large tensile stress were observed at the presence of residual indium atoms. RSM disclosed the mosaicity, and the GIXRD was conducted to investigate the depth dependences of crystal quality and strain states. XPS depth profile of indium contents indicated that residual indium atoms deteriorated the crystal quality of GaN not only by producing lattice mismatch at the interface of InGaN and GaN but also by diffusing into GaN overlayers. Accordingly, two solutions were proposed to improve the efficiency of self-patterned lateral epitaxial overgrowth method. This research goes a further step in resolving the urgent substrate problem in GaN fabrication.

  3. Controlling nested wrinkle morphology through the boundary effect on narrow-band thin films

    NASA Astrophysics Data System (ADS)

    Xu, Hanyang; Shi, Tielin; Liao, Guanglan; Xia, Qi

    2017-07-01

    We describe the formation of nested wrinkles created by the thermal mismatch between a narrow-band thin film and a compliant substrate. When a film is described as "narrow-band", it literally means that the film band width is much shorter than its length; more precisely, it means that the width is comparable with the wavelength of the wrinkles. A silicon mask was used during film sputtering to create narrow-band films on poly (dimethylsiloxane) substrate, thus creating regular boundaries to steer local stresses and control wrinkle morphology. Disordered nano-scale wrinkles were found nested within highly ordered micro-scale sinusoidal wrinkles. The formation of nested wrinkles was explained through the amplitude and wavelength saturation of nano-scale wrinkles. The disordered morphology of nano-scale wrinkles and the highly ordered morphology of micro-scale wrinkles were explained by using the boundary effect.

  4. Energy spectrum and transport in narrow HgTe quantum wells

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Germanenko, A. V., E-mail: Alexander.Germanenko@urfu.ru; Minkov, G. M.; Rut, O. E.

    The results of an experimental study of the transport phenomena and the hole energy spectrum of two-dimensional systems in the quantum well of HgTe zero-gap semiconductor with normal arrangement of quantum-confinement subbands are presented. An analysis of the experimental data allows us to reconstruct the carrier energy spectrum near the hole subband extrema. The results are interpreted using the standard kP model.

  5. Linewidth narrowing for 31Phosphorus MRI of cell membranes

    NASA Astrophysics Data System (ADS)

    Barrett, Sean; Frey, Merideth; Madri, Joseph; Michaud, Michael

    2011-03-01

    Most 31 P Magnetic Resonance Spectroscopy studies of tissues try to avoid contamination by a relatively large, but broad, spectral feature attributed to cell membrane phospholipids. MRI using this broad 31 P membrane spectrum is not even attempted, since the spatial resolution and signal-to-noise would be poor, relative to conventional MRI using the narrow 1 H water spectrum. This long-standing barrier has been overcome by a novel pulse sequence, recently discovered in fundamental quantum computation research, which narrows the broad 31 P spectrum by ~ 1000 × . Applying time-dependent gradients in synch with a repeating pulse block enables a new route to high spatial resolution, 3D 31 P MRI of the soft solid components of cells and tissues. So far, intact and sectioned samples of ex vivo fixed mouse organs have been imaged, with (sub-mm)3 voxels. Extending the reach of MRI to broad spectra in natural and artificial tissues opens a new window into cells, enabling progress in biomedical research. W.J. Thoma et al., J. MR 61, 141 (1985); E.J. Murphy et al., MR Med 12, 282 (1989); R. McNamara et al., NMR Biomed 7, 237 (1994).

  6. Precise measurement of ultra-narrow laser linewidths using the strong coherent envelope

    NASA Astrophysics Data System (ADS)

    Huang, Shihong; Zhu, Tao; Liu, Min; Huang, Wei

    2017-02-01

    Laser linewidth narrowing down to kHz or even Hz is an important topic in areas like clock synchronization technology, laser radars, quantum optics, and high-precision detection. Conventional decoherence measurement methods like delayed self-heterodyne/homodyne interferometry cannot measure such narrow linewidths accurately. This is because a broadening of the Gaussian spectrum, which hides the laser’s intrinsic Lorentzian linewidth, cannot be avoided. Here, we introduce a new method using the strong coherent envelope to characterize the laser’s intrinsic linewidth through self-coherent detection. This method can eliminate the effect of the broadened Gaussian spectrum induced by the 1/f frequency noise. We analyze, in detail, the relationship between intrinsic laser linewidth, contrast difference with the second peak and the second trough (CDSPST) of the strong coherent envelope, and the length of the delaying fiber. The correct length for the delaying fiber can be chosen by combining the estimated laser linewidth (Δfest) with a specific CDSPST (ΔS) to obtain the accurate laser linewidth (Δf). Our results indicate that this method can be used as an accurate detection tool for measurements of narrow or super-narrow linewidths.

  7. 1.7  μm band narrow-linewidth tunable Raman fiber lasers pumped by spectrum-sliced amplified spontaneous emission.

    PubMed

    Zhang, Peng; Wu, Di; Du, Quanli; Li, Xiaoyan; Han, Kexuan; Zhang, Lizhong; Wang, Tianshu; Jiang, Huilin

    2017-12-10

    A 1.7 μm band tunable narrow-linewidth Raman fiber laser based on spectrally sliced amplified spontaneous emission (SS-ASE) and multiple filter structures is proposed and experimentally demonstrated. In this scheme, an SS-ASE source is employed as a pump source in order to avoid stimulated Brillouin scattering. The ring configuration includes a 500 m long high nonlinear optical fiber and a 10 km long dispersion shifted fiber as the gain medium. A segment of un-pumped polarization-maintaining erbium-doped fiber is used to modify the shape of the spectrum. Furthermore, a nonlinear polarization rotation scheme is applied as the wavelength selector to generate lasers. A high-finesse ring filter and a ring filter are used to narrow the linewidth of the laser, respectively. We demonstrate tuning capabilities of a single laser over 28 nm between 1652 nm and 1680 nm by adjusting the polarization controller (PC) and tunable filter. The tunable laser has a 0.023 nm effective linewidth with the high-finesse ring filter. The stable multi-wavelength laser operation of up to four wavelengths can be obtained by adjusting the PC carefully when the pump power increases.

  8. The Neural Substrates of Cognitive Control Deficits in Autism Spectrum Disorders

    PubMed Central

    Solomon, Marjorie; Ozonoff, Sally; Ursu, Stefan; Ravizza, Susan; Cummings, Neil; Ly, Stanford; Carter, Cameron

    2009-01-01

    Executive functions deficits are among the most frequently reported symptoms of autism spectrum disorders (ASDs), however, there have been few functional magnetic resonance imaging (fMRI) studies that investigate the neural substrates of executive functions deficits in ASDs, and only one in adolescents. The current study examined cognitive control –the ability to maintain task context online to support adaptive functioning in the face of response competition—in 22 adolescents aged 12–18 with autism spectrum disorders and 23 age, gender, and IQ matched typically developing subjects. During the cue phase of the task, where subjects must maintain information online to overcome a prepotent response tendency, typically developing subjects recruited significantly more anterior frontal (BA 10), parietal (BA 7, 40), and occipital regions (BA 18) for high control trials (25% of trials) versus low control trials (75% of trials). Both groups showed similar activation for low control cues, however the ASD group exhibited significantly less activation for high control cues. Functional connectivity analysis using time series correlation, factor analysis, and beta series correlation methods provided convergent evidence that the ASD group exhibited lower levels of functional connectivity and less network integration between frontal, parietal, and occipital regions. In the typically developing group, fronto-parietal connectivity was related to lower error rates on high control trials. In the autism group, reduced fronto-parietal connectivity was related to attention deficit hyperactivity disorder symptoms. PMID:19410583

  9. Photovoltaic measurement of bandgap narrowing in moderately doped silicon

    NASA Astrophysics Data System (ADS)

    del Alamo, Jesus A.; Swanson, Richard M.; Lietoila, Arto

    1983-05-01

    Solar cells have been fabricated on n-type and p-type moderately doped Si. The shrinkage of the Si bandgap has been obtained by measuring the internal quantum efficiency in the near infrared spectrum ( hv = 1.00-1.25 eV) around the fundamental absorption edge. The results agree with previous optical measurements of bandgap narrowing in Si. It is postulated that this optically-determined bandgap narrowing is the rigid shrinkage of the forbidden gap due to many-body effects. The "device bandgap narrowing" obtained by measuring the pn product in bipolar devices leads to discrepant values because (i) the density of states in the conduction and valence band is modified due to the potential fluctuations originated in the variations in local impurity density, and (ii) the influence of Fermi-Dirac statistics.

  10. Fabrication of Ag nanostructures with remarkable narrow plasmonic resonances by glancing angle deposition

    NASA Astrophysics Data System (ADS)

    Abbasian, Sara; Moshaii, Ahmad; Vayghan, Nader Sobhkhiz; Nikkhah, Maryam

    2018-05-01

    Glancing angle deposition (GLAD) is an efficient and inexpensive method to fabricate nanostructures with diverse complexities. However, this method has a limitation in fabrication of plasmonic nanostructures with narrow resonance peaks causing that the GLAD-nanostructures have rarely been used for refractive-index sensing. In this work, we proposed two approaches to overcome this limitation of GLAD and to fabricate Ag nanostructures with narrow plasmonic peaks. In the first approach, we introduce an effective method for seeding modification of the substrate and then growing the Ag nanocolumns on such seeded layer. The optical characterization shows that such pre-seeding of the substrate leads to nearly 40% narrowing of the plasmonic peak. In another approach, the nanostructures are grown by GLAD on a bare substrate and then are annealed at 200-400 °C. Such annealing converts the nanostructures to nanodomes with large inter-particle distances and about 60% reduction of their plasmonic width. Also, the annealing of the nanostructures at 400 °C provides a twofold improvement in figure of merit of sensing of the nanostructures. This improvement makes the GLAD comparative to other expensive alternate methods for fabrication of plasmonic sensors. In addition, the experimental plasmonic peaks are reproduced in a proper numerical simulation for similar nanostructures.

  11. Acquisition and visualization techniques for narrow spectral color imaging.

    PubMed

    Neumann, László; García, Rafael; Basa, János; Hegedüs, Ramón

    2013-06-01

    This paper introduces a new approach in narrow-band imaging (NBI). Existing NBI techniques generate images by selecting discrete bands over the full visible spectrum or an even wider spectral range. In contrast, here we perform the sampling with filters covering a tight spectral window. This image acquisition method, named narrow spectral imaging, can be particularly useful when optical information is only available within a narrow spectral window, such as in the case of deep-water transmittance, which constitutes the principal motivation of this work. In this study we demonstrate the potential of the proposed photographic technique on nonunderwater scenes recorded under controlled conditions. To this end three multilayer narrow bandpass filters were employed, which transmit at 440, 456, and 470 nm bluish wavelengths, respectively. Since the differences among the images captured in such a narrow spectral window can be extremely small, both image acquisition and visualization require a novel approach. First, high-bit-depth images were acquired with multilayer narrow-band filters either placed in front of the illumination or mounted on the camera lens. Second, a color-mapping method is proposed, using which the input data can be transformed onto the entire display color gamut with a continuous and perceptually nearly uniform mapping, while ensuring optimally high information content for human perception.

  12. Metabolic engineering to expand the substrate spectrum of Pseudomonas putida toward sucrose.

    PubMed

    Löwe, Hannes; Schmauder, Lukas; Hobmeier, Karina; Kremling, Andreas; Pflüger-Grau, Katharina

    2017-08-01

    Sucrose is an important disaccharide used as a substrate in many industrial applications. It is a major component of molasses, a cheap by-product of the sugar industry. Unfortunately, not all industrially relevant organisms, among them Pseudomonas putida, are capable of metabolizing sucrose. We chose a metabolic engineering approach to circumvent this blockage and equip P. putida with the activities necessary to consume sucrose. Therefore, we constructed a pair of broad-host range mini-transposons (pSST - sucrose splitting transposon), carrying either cscA, encoding an invertase able to split sucrose into glucose and fructose, or additionally cscB, encoding a sucrose permease. Introduction of cscA was sufficient to convey sucrose consumption and the additional presence of cscB had no further effect, though the sucrose permease was built and localized to the membrane. Sucrose was split extracellularly by the activity of the invertase CscA leaking out of the cell. The transposons were also used to confer sucrose consumption to Cupriavidus necator. Interestingly, in this strain, CscB acted as a glucose transporter, such that C. necator also gained the ability to grow on glucose. Thus, the pSST transposons are functional tools to extend the substrate spectrum of Gram-negative bacterial strains toward sucrose. © 2017 The Authors. MicrobiologyOpen published by John Wiley & Sons Ltd.

  13. Extensive peptide and natural protein substrate screens reveal that mouse caspase-11 has much narrower substrate specificity than caspase-1

    PubMed Central

    Ramirez, Monica L. Gonzalez; Poreba, Marcin; Snipas, Scott J.; Groborz, Katarzyna; Drag, Marcin; Salvesen, Guy S.

    2018-01-01

    Inflammatory cell death, or pyroptosis, is triggered by pathogenic infections or events. It is executed by caspase-1 (in the canonical pyroptosis pathway) or caspase-11 (noncanonical pathway), each via production of a cell-lytic domain from the pyroptosis effector protein gasdermin D through specific and limited proteolysis. Pyroptosis is accompanied by the release of inflammatory mediators, including the proteolytically processed forms of interleukin-1β (IL-1β) and IL-18. Given the similar inflammatory outcomes of the canonical and noncanonical pyroptosis pathways, we hypothesized that caspase-1 and -11 should have very similar activities and substrate specificities. To test this hypothesis, we purified recombinant murine caspases and analyzed their primary specificities by massive hybrid combinatorial substrate library (HyCoSuL) screens. We correlated the substrate preferences of each caspase with their activities on the recombinant natural substrates IL-1β, IL-18, and gasdermin D. Although we identified highly selective and robust peptidyl substrates for caspase-1, we were unable to do so for caspase-11, because caspase-1 cleaved even the best caspase-11 substrates equally well. Caspase-1 rapidly processed pro-IL-1β and -18, but caspase-11 processed these two pro-ILs extremely poorly. However, both caspase-1 and -11 efficiently produced the cell-lytic domain from the gasdermin D precursor. We hypothesize that caspase-11 may have evolved a specific exosite to selectively engage pyroptosis without directly activating pro-IL-1β or -18. In summary, comparing the activities of caspase-1 and -11 in HyCoSuL screens and with three endogenous protein substrates, we conclude that caspase-11 has highly restricted substrate specificity, preferring gasdermin D over all other substrates examined. PMID:29414788

  14. Extensive peptide and natural protein substrate screens reveal that mouse caspase-11 has much narrower substrate specificity than caspase-1.

    PubMed

    Ramirez, Monica L Gonzalez; Poreba, Marcin; Snipas, Scott J; Groborz, Katarzyna; Drag, Marcin; Salvesen, Guy S

    2018-05-04

    Inflammatory cell death, or pyroptosis, is triggered by pathogenic infections or events. It is executed by caspase-1 (in the canonical pyroptosis pathway) or caspase-11 (noncanonical pathway), each via production of a cell-lytic domain from the pyroptosis effector protein gasdermin D through specific and limited proteolysis. Pyroptosis is accompanied by the release of inflammatory mediators, including the proteolytically processed forms of interleukin-1β (IL-1β) and IL-18. Given the similar inflammatory outcomes of the canonical and noncanonical pyroptosis pathways, we hypothesized that caspase-1 and -11 should have very similar activities and substrate specificities. To test this hypothesis, we purified recombinant murine caspases and analyzed their primary specificities by massive hybrid combinatorial substrate library (HyCoSuL) screens. We correlated the substrate preferences of each caspase with their activities on the recombinant natural substrates IL-1β, IL-18, and gasdermin D. Although we identified highly selective and robust peptidyl substrates for caspase-1, we were unable to do so for caspase-11, because caspase-1 cleaved even the best caspase-11 substrates equally well. Caspase-1 rapidly processed pro-IL-1β and -18, but caspase-11 processed these two pro-ILs extremely poorly. However, both caspase-1 and -11 efficiently produced the cell-lytic domain from the gasdermin D precursor. We hypothesize that caspase-11 may have evolved a specific exosite to selectively engage pyroptosis without directly activating pro-IL-1β or -18. In summary, comparing the activities of caspase-1 and -11 in HyCoSuL screens and with three endogenous protein substrates, we conclude that caspase-11 has highly restricted substrate specificity, preferring gasdermin D over all other substrates examined. © 2018 by The American Society for Biochemistry and Molecular Biology, Inc.

  15. Characteristics of The Narrow Spectrum Beams Used in the Secondary Standard Dosimetry Laboratory at the Lebanese Atomic Energy Commission.

    PubMed

    Melhem, N; El Balaa, H; Younes, G; Al Kattar, Z

    2017-06-15

    The Secondary Standard Dosimetry Laboratory at the Lebanese Atomic Energy Commission has different calibration methods for various types of dosimeters used in industrial, military and medical fields. The calibration is performed using different beams of X-rays (low and medium energy) and Gamma radiation delivered by a Cesium 137 source. The Secondary Standard Dosimetry laboratory in charge of calibration services uses different protocols for the determination of high and low air kerma rate and for narrow and wide series. In order to perform this calibration work, it is very important to identify all the beam characteristics for the different types of sources and qualities of radiation. The following work describes the methods used for the determination of different beam characteristics and calibration coefficients with their uncertainties in order to enhance the radiation protection of workers and patient applications in the fields of medical diagnosis and industrial X-ray. All the characteristics of the X-ray beams are determined for the narrow spectrum series in the 40 and 200 keV range where the inherent filtration, the current intensity, the high voltage, the beam profile and the total uncertainty are the specific characteristics of these X-ray beams. An X-ray software was developed in order to visualize the reference values according to the characteristics of each beam. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  16. The influence of temperature on narrow I 1 and I 2 lines in the luminescence spectrum of Ni0.6Zn0.4O

    NASA Astrophysics Data System (ADS)

    Sokolov, V. I.; Pustovarov, V. A.; Ivanov, V. Yu.; Gruzdev, N. B.; Sokolov, P. S.; Baranov, A. N.

    2014-05-01

    The behavior of the luminescence spectrum of solid solution Ni0.6Zn0.4O, in which two intense narrow lines were recently discovered, is investigated as a function of temperature. It is shown that the intensity of one of the lines drops in accordance with the Mott law with increasing temperature in the range between 10 and 50 K. The lines experience broadening, and the ratio of their intensities changes. In addition, the lines shift toward lower energies. This shift and broadening of both lines occur differently, suggesting that they are of different nature.

  17. Omnidirectional narrow optical filters for circularly polarized light in a nanocomposite structurally chiral medium.

    PubMed

    Avendaño, Carlos G; Palomares, Laura O

    2018-04-20

    We consider the propagation of electromagnetic waves throughout a nanocomposite structurally chiral medium consisting of metallic nanoballs randomly dispersed in a structurally chiral material whose dielectric properties can be represented by a resonant effective uniaxial tensor. It is found that an omnidirectional narrow pass band and two omnidirectional narrow band gaps are created in the blue optical spectrum for right and left circularly polarized light, as well as narrow reflection bands for right circularly polarized light that can be controlled by varying the light incidence angle and the filling fraction of metallic inclusions.

  18. Biochemistry Students' Ideas about How an Enzyme Interacts with a Substrate

    ERIC Educational Resources Information Center

    Linenberger, Kimberly J.; Bretz, Stacey Lowery

    2015-01-01

    Enzyme-substrate interactions are a fundamental concept of biochemistry that is built upon throughout multiple biochemistry courses. Central to understanding enzyme-substrate interactions is specific knowledge of exactly how an enzyme and substrate interact. Within this narrower topic, students must understand the various binding sites on an…

  19. Virtual substrate method for nanomaterials characterization

    PubMed Central

    Da, Bo; Liu, Jiangwei; Yamamoto, Mahito; Ueda, Yoshihiro; Watanabe, Kazuyuki; Cuong, Nguyen Thanh; Li, Songlin; Tsukagoshi, Kazuhito; Yoshikawa, Hideki; Iwai, Hideo; Tanuma, Shigeo; Guo, Hongxuan; Gao, Zhaoshun; Sun, Xia; Ding, Zejun

    2017-01-01

    Characterization techniques available for bulk or thin-film solid-state materials have been extended to substrate-supported nanomaterials, but generally non-quantitatively. This is because the nanomaterial signals are inevitably buried in the signals from the underlying substrate in common reflection-configuration techniques. Here, we propose a virtual substrate method, inspired by the four-point probe technique for resistance measurement as well as the chop-nod method in infrared astronomy, to characterize nanomaterials without the influence of underlying substrate signals from four interrelated measurements. By implementing this method in secondary electron (SE) microscopy, a SE spectrum (white electrons) associated with the reflectivity difference between two different substrates can be tracked and controlled. The SE spectrum is used to quantitatively investigate the covering nanomaterial based on subtle changes in the transmission of the nanomaterial with high efficiency rivalling that of conventional core-level electrons. The virtual substrate method represents a benchmark for surface analysis to provide ‘free-standing' information about supported nanomaterials. PMID:28548114

  20. Surface study of graphene ink for fine solid lines printed on BOPP Substrate in micro-flexographic printing using XPS analysis technique

    NASA Astrophysics Data System (ADS)

    Hassan, S.; Yusof, M. S.; Embong, Z.; Ding, S.; Maksud, M. I.

    2018-01-01

    Micro-flexographic printing is a combination of flexography and micro-contact printing technique. It is a new printing method for fine solid lines printing purpose. Graphene material has been used as depositing agent or printing ink in other printing technique like inkjet printing. This graphene ink is printed on biaxially oriented polypropylene (BOPP) by using Micro-flexographic printing technique. The choose of graphene as a printing ink is due to its wide application in producing electronic and micro-electronic devices such as Radio-frequency identification (RFID) and printed circuit board. The graphene printed on the surface of BOPP substrate was analyzed using X-Ray Photoelectron Spectroscopy (XPS). The positions for each synthetic component in the narrow scan are referred to the electron binding energy (eV). This research is focused on two narrow scan regions which are C 1s and O 1s. Further discussion of the narrow scan spectrum will be explained in detail. From the narrow scan analysis, it is proposed that from the surface adhesive properties of graphene, it is suitable as an alternative printing ink medium for Micro-flexographic printing technique in printing multiple fine solid lines at micro to nano scale feature.

  1. Development of stable, narrow spectral line-width, fiber delivered laser source for spin exchange optical pumping

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Liu, Bo; Tong, Xin; Jiang, Chenyang

    2015-06-05

    In this study, we developed a stable, narrow spectral line-width, fiber delivered laser source for spin exchange optical pumping. An optimized external cavity equipped with an off-the-shelf volume holographic grating narrowed the spectral line-width of a 100 W high-power diode laser and stabilized the laser spectrum. The laser spectrum showed a high side mode suppression ratio of >30 dB and good long-term stability (center wavelength drifting within ±0.002 nm during 220 h of operation). Finally, our laser is delivered by a multimode fiber with power ~70 W, center wavelength of 794.77 nm, and spectral bandwidth of ~0.12 nm.

  2. CT demonstration of pharyngeal narrowing in adult obstructive sleep apnea

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bohlman, M.E.; Haponik, E.F.; Smith, P.L.

    Sleep apnea is a major cause of daytime hypersomnolence. Among the proposed etiologies, focal obstruction of the airways at the level of the pharynx has been suggested but not proven. Using computed tomography, the cross-sectional area of the airway can be readily assessed. Thirty-three adults with clinically proven sleep apnea and 12 normal adults underwent systematic computed tomography of the neck. Significant airway narrowing was demonstrated in all the patients with obstructive sleep apnea, whereas no such narrowing was seen in the controls. In 11, the narrowing was at a single level, whereas in 22 patients two or more levelsmore » were affected. This study has shown that a structurally abnormal airway may serve as an anatomic substrate for the development of sleep apnea. On the basis of this evidence, uvulopalatopharyngoplasty has been performed in two patients with relief of symptoms in one.« less

  3. Narrow-spectrum ß-lactam monotherapy in hospital treatment of community-acquired pneumonia: a register-based cohort study.

    PubMed

    Rhedin, S; Galanis, I; Granath, F; Ternhag, A; Hedlund, J; Spindler, C; Naucler, P

    2017-04-01

    To assess the clinical effect of empirical treatment with narrow-spectrum ß-lactam monotherapy (NSBM) versus broad-spectrum ß-lactam monotherapy (BSBM) in non-severe community-acquired pneumonia (CAP). Hospitalized patients ≥18 years with CAP who received initial NSBM or BSBM, with a severity score according to CRB-65≤2 (C=confusion, R=respiratory rate >30/min, B=systolic blood pressure <90 mmHg or diastolic blood pressure ≤60 mmHg, 65= ≥65 years), in the Swedish Pneumonia Register from 2008 to 2011 were included. Primary outcome was 30-day mortality. Secondary outcomes were 90-day mortality, treatment at intensive care unit (ICU), and length of stay (LOS). Propensity score matching was performed to account for differences in baseline characteristics. There were 5961 patients with CRB-65≤1 and 1344 patients with CRB-65=2. In the propensity score matched cohorts the 30-day mortality was 40/1827 (2.2%) with NSBM and 56/1827 (3.1%) with BSBM in CRB-65≤1, and 57/524 (10.9%) and 51/524 (9.7%), respectively, in CRB-65=2. No significant differences in 30-day mortality were observed between NSBM and BSBM in patients with CRB-65≤1 or CRB-65=2, OR 1.41 (95% CI 0.94-2.14) and 0.88 (95% CI 0.59-1.32), respectively. There was no significant difference in 90-day mortality. Patients who received BSBM were more often treated at ICU and had longer LOS. Empirical NSBM appears to be effective in the majority of hospitalized immunocompetent adults with non-severe CAP and should be further evaluated in randomized trials. Copyright © 2016 European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

  4. Numerical simulation of evaluation of surface breaking cracks by array-lasers generated narrow-band SAW

    NASA Astrophysics Data System (ADS)

    Dong, Li-Ming; Ni, Chen-Yin; Shen, Zhong-Hua; Ni, Xiao-Wu

    2011-09-01

    Most of the factors limiting the extensive application of laser-based ultrasonic for nondestructive evaluation of surface breaking crack are its poor sensitivity, low efficiency relative to conventional contact ultrasonic methods and limit on the dimension of the cracks. For this reason, a new technique that multiplepulse narrow-band ultrasound generated by laser arrays has been proposed. It is found that crack detection dependent on spectrum of narrow-band ultrasound generated by laser arrays can be operated with low amplitude requirements. In this paper, the narrow-band ultrasound generated by pulse laser arrays interacting with surface breaking cracks has been simulated in detail by the finite element method (FEM) according to the thermoelastic theory. The pulsed array lasers were assumed to be transient heat source, and the surface acoustic wave (SAW) which propagating on the top of the plate was computed based on thermoelastic theory. Then the frequency spectrums of both reflected waves by crack and transmission ones through crack were compared with the direct waves. Results demonstrate that multiple-frequency components of the narrow-band ultrasound were varied with change of the depth of surface breaking cracks significantly, which provides the possibility for precise evaluation of surface breaking cracks.

  5. Neural activity underlying motor-action preparation and cognitive narrowing in approach-motivated goal states.

    PubMed

    Gable, Philip A; Threadgill, A Hunter; Adams, David L

    2016-02-01

    High-approach-motivated (pre-goal) positive affect states encourage tenacious goal pursuit and narrow cognitive scope. As such, high approach-motivated states likely enhance the neural correlates of motor-action preparation to aid in goal acquisition. These neural correlates may also relate to the cognitive narrowing associated with high approach-motivated states. In the present study, we investigated motor-action preparation during pre-goal and post-goal states using an index of beta suppression over the motor cortex. The results revealed that beta suppression was greatest in pre-goal positive states, suggesting that higher levels of motor-action preparation occur during high approach-motivated positive states. Furthermore, beta and alpha suppression in the high approach-motivated positive states predicted greater cognitive narrowing. These results suggest that approach-motivated pre-goal states engage the neural substrates of motor-action preparation and cognitive narrowing. Individual differences in motor-action preparation relate to the degree of cognitive narrowing.

  6. Narrow-band injection seeding of a terahertz frequency quantum cascade laser: Selection and suppression of longitudinal modes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nong, Hanond, E-mail: Nong.Hanond@rub.de; Markmann, Sergej; Hekmat, Negar

    2014-09-15

    A periodically poled lithium niobate (PPLN) crystal with multiple poling periods is used to generate tunable narrow-bandwidth THz pulses for injection seeding a quantum cascade laser (QCL). We demonstrate that longitudinal modes of the quantum cascade laser close to the gain maximum can be selected or suppressed according to the seed spectrum. The QCL emission spectra obtained by electro-optic sampling from the quantum cascade laser, in the most favorable case, shows high selectivity and amplification of the longitudinal modes that overlap the frequency of the narrow-band seed. Proper selection of the narrow-band THz seed from the PPLN crystal discretely tunesmore » the longitudinal mode emission of the quantum cascade laser. Moreover, the THz wave build-up within the laser cavity is studied as a function of the round-trip time. When the seed frequency is outside the maximum of the gain spectrum the laser emission shifts to the preferential longitudinal mode.« less

  7. High power narrow-band fiber-based ASE source.

    PubMed

    Schmidt, O; Rekas, M; Wirth, C; Rothhardt, J; Rhein, S; Kliner, A; Strecker, M; Schreiber, T; Limpert, J; Eberhardt, R; Tünnermann, A

    2011-02-28

    In this paper we describe a high power narrow-band amplified spontaneous emission (ASE) light source at 1030 nm center wavelength generated in an Yb-doped fiber-based experimental setup. By cutting a small region out of a broadband ASE spectrum using two fiber Bragg gratings a strongly constrained bandwidth of 12±2 pm (3.5±0.6 GHz) is formed. A two-stage high power fiber amplifier system is used to boost the output power up to 697 W with a measured beam quality of M2≤1.34. In an additional experiment we demonstrate a stimulated Brillouin scattering (SBS) suppression of at least 17 dB (theoretically predicted ~20 dB), which is only limited by the dynamic range of the measurement and not by the onset of SBS when using the described light source. The presented narrow-band ASE source could be of great interest for brightness scaling applications by beam combination, where SBS is known as a limiting factor.

  8. Mid-wave infrared narrow bandwidth guided mode resonance notch filter.

    PubMed

    Zhong, Y; Goldenfeld, Z; Li, K; Streyer, W; Yu, L; Nordin, L; Murphy, N; Wasserman, D

    2017-01-15

    We have designed, fabricated, and characterized a guided mode resonance notch filter operating in the technologically vital mid-wave infrared (MWIR) region of the electromagnetic spectrum. The filter provides a bandstop at λ≈4.1  μm, with a 12 dB extinction on resonance. In addition, we demonstrate a high transmission background (>80%), less than 6% transmission on resonance, and an ultra-narrow bandwidth transmission notch (10  cm-1). Our filter is optically characterized using angle- and polarization-dependent Fourier transform infrared spectroscopy, and simulated using rigorous coupled-wave analysis (RCWA) with excellent agreement between simulations and our experimental results. Using our RCWA simulations, we are able to identify the optical modes associated with the transmission dips of our filter. The presented structure offers a potential route toward narrow-band laser filters in the MWIR.

  9. Narrow Angle movie

    NASA Technical Reports Server (NTRS)

    1999-01-01

    This brief three-frame movie of the Moon was made from three Cassini narrow-angle images as the spacecraft passed by the Moon on the way to its closest approach with Earth on August 17, 1999. The purpose of this particular set of images was to calibrate the spectral response of the narrow-angle camera and to test its 'on-chip summing mode' data compression technique in flight. From left to right, they show the Moon in the green, blue and ultraviolet regions of the spectrum in 40, 60 and 80 millisecond exposures, respectively. All three images have been scaled so that the brightness of Crisium basin, the dark circular region in the upper right, is the same in each image. The spatial scale in the blue and ultraviolet images is 1.4 miles per pixel (2.3 kilometers). The original scale in the green image (which was captured in the usual manner and then reduced in size by 2x2 pixel summing within the camera system) was 2.8 miles per pixel (4.6 kilometers). It has been enlarged for display to the same scale as the other two. The imaging data were processed and released by the Cassini Imaging Central Laboratory for Operations (CICLOPS) at the University of Arizona's Lunar and Planetary Laboratory, Tucson, AZ.

    Photo Credit: NASA/JPL/Cassini Imaging Team/University of Arizona

    Cassini, launched in 1997, is a joint mission of NASA, the European Space Agency and Italian Space Agency. The mission is managed by NASA's Jet Propulsion Laboratory, Pasadena, CA, for NASA's Office of Space Science, Washington DC. JPL is a division of the California Institute of Technology, Pasadena, CA.

  10. Measurement of the surface wavelength distribution of narrow-band radiation by a colorimetric method

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kraiskii, A V; Mironova, T V; Sultanov, T T

    2010-09-10

    A method is suggested for determining the wavelength of narrow-band light from a digital photograph of a radiating surface. The digital camera used should be appropriately calibrated. The accuracy of the wavelength measurement is better than 1 nm. The method was tested on the yellow doublet of mercury spectrum and on the adjacent continuum of the incandescent lamp radiation spectrum. By means of the method suggested the homogeneity of holographic sensor swelling was studied in stationary and transient cases. (laser applications and other topics in quantum electronics)

  11. A Martian PFS average spectrum: Comparison with ISO SWS

    NASA Astrophysics Data System (ADS)

    Formisano, V.; Encrenaz, T.; Fonti, S.; Giuranna, M.; Grassi, D.; Hirsh, H.; Khatuntsev, I.; Ignatiev, N.; Lellouch, E.; Maturilli, A.; Moroz, V.; Orleanski, P.; Piccioni, G.; Rataj, M.; Saggin, B.; Zasova, L.

    2005-08-01

    The evaluation of the planetary Fourier spectrometer performance at Mars is presented by comparing an average spectrum with the ISO spectrum published by Lellouch et al. [2000. Planet. Space Sci. 48, 1393.]. First, the average conditions of Mars atmosphere are compared, then the mixing ratios of the major gases are evaluated. Major and minor bands of CO 2 are compared, from the point of view of features characteristics and bands depth. The spectral resolution is also compared using several solar lines. The result indicates that PFS radiance is valid to better than 1% in the wavenumber range 1800-4200 cm -1 for the average spectrum considered (1680 measurements). The PFS monochromatic transfer function generates an overshooting on the left-hand side of strong narrow lines (solar or atmospheric). The spectral resolution of PFS is of the order of 1.3 cm -1 or better. A large number of narrow features to be identified are discovered.

  12. Narrow-band filters for ocean colour imager

    NASA Astrophysics Data System (ADS)

    Krol, Hélène; Chazallet, Frédéric; Archer, Julien; Kirchgessner, Laurent; Torricini, Didier; Grèzes-Besset, Catherine

    2017-11-01

    During the last few years, the evolution of deposition technologies of optical thin films coatings and associated in-situ monitoring methods enables us today to successfully answer the increasingly request of space systems for Earth observation. Geostationary satellite COMS-1 (Communication, Ocean, Meteorological Satellite-1) of Astrium has the role of ensuring meteorological observation as well as monitoring of the oceans. It is equipped with a colour imager to observe the marine ecosystem through 8 bands in the visible spectrum with a ground resolution of 500m. For that, this very high technology instrument is constituted with a filters wheel in front of the oceanic colour imager with 8 narrow band filters carried out and qualified by Cilas.

  13. Achieving an ultra-narrow multiband light absorption meta-surface via coupling with an optical cavity.

    PubMed

    Liu, Zhengqi; Liu, Guiqiang; Liu, Xiaoshan; Huang, Shan; Wang, Yan; Pan, Pingping; Liu, Mulin

    2015-06-12

    Resonant plasmonic and metamaterial absorbers are of particular interest for applications in a wide variety of nanotechnologies including thermophotovoltaics, photothermal therapy, hot-electron collection and biosensing. However, it is rather challenging to realize ultra-narrow absorbers using plasmonic materials due to large optical losses in metals that inevitably decrease the quality of optical resonators. Here, we theoretically report methods to achieve an ultra-narrow light absorption meta-surface by using photonic modes of the optical cavities, which strongly couple with the plasmon resonances of the metallic nanostructures. Multispectral light absorption with absorption amplitude exceeding 99% and a bandwidth approaching 10 nm is achieved at the optical frequencies. Moreover, by introducing a thick dielectric coupling cavity, the number of absorption bands can be strongly increased and the bandwidth can even be narrowed to less than 5 nm due to the resonant spectrum splitting enabled by strong coupling between the plasmon resonances and the optical cavity modes. Designing such optical cavity-coupled meta-surface structures is a promising route for achieving ultra-narrow multiband absorbers, which can be used in absorption filters, narrow-band multispectral thermal emitters and thermophotovoltaics.

  14. Specificity of a protein-protein interface: local dynamics direct substrate recognition of effector caspases.

    PubMed

    Fuchs, Julian E; von Grafenstein, Susanne; Huber, Roland G; Wallnoefer, Hannes G; Liedl, Klaus R

    2014-04-01

    Proteases are prototypes of multispecific protein-protein interfaces. Proteases recognize and cleave protein and peptide substrates at a well-defined position in a substrate binding groove and a plethora of experimental techniques provide insights into their substrate recognition. We investigate the caspase family of cysteine proteases playing a key role in programmed cell death and inflammation, turning caspases into interesting drug targets. Specific ligand binding to one particular caspase is difficult to achieve, as substrate specificities of caspase isoforms are highly similar. In an effort to rationalize substrate specificity of two closely related caspases, we investigate the substrate promiscuity of the effector Caspases 3 and 7 by data mining (cleavage entropy) and by molecular dynamics simulations. We find a strong correlation between binding site rigidity and substrate readout for individual caspase subpockets explaining more stringent substrate readout of Caspase 7 via its narrower conformational space. Caspase 3 subpockets S3 and S4 show elevated local flexibility explaining the more unspecific substrate readout of that isoform in comparison to Caspase 7. We show by in silico exchange mutations in the S3 pocket of the proteases that a proline residue in Caspase 7 contributes to the narrowed conformational space of the binding site. These findings explain the substrate specificities of caspases via a mechanism of conformational selection and highlight the crucial importance of binding site local dynamics in substrate recognition of proteases. Proteins 2014; 82:546-555. © 2013 Wiley Periodicals, Inc. Copyright © 2013 The Authors Proteins: Structure, Function, and Bioinformatics Published by Wiley Periodicals, Inc.

  15. The solar gamma ray spectrum between 4 and 8 MeV

    NASA Technical Reports Server (NTRS)

    Ramaty, R.; Kozlovsky, B.; Suri, A. N.

    1976-01-01

    The properties of nuclear gamma ray emission in the 4 to 8 MeV range were evaluated. This emission consists of broad and narrow lines resulting from nuclear reactions of energetic H, He, C and O nuclei with ambient matter. Calculations were compared with observations of the 1972, August 4 flare and show that: (1) essentially all the observed radiation in the 4 to 8 MeV region is to the superposition of broad and narrow lines of nuclear origin with almost no contribution from other mechanisms; (2) the accelerated particles in the energy region from about 10 to 100 MeV/amu have a relatively flat Energy spectrum; (3) the calculated gamma ray spectrum, obtained from an isotropic distribution of accelerated particles, fits the observed spectrum better than the spectrum derived from an anisotropic distribution for which the particles' velocity vectors point towards the photosphere; and (4) it is possible to set a stringent upper limit on the ratio of relativistic electrons to protons in flares, consistent with the small, but finite, electron-to-proton ratio in galactic cosmic rays.

  16. Is Perceptual Narrowing Too Narrow?

    ERIC Educational Resources Information Center

    Cashon, Cara H.; Denicola, Christopher A.

    2011-01-01

    There is a growing list of examples illustrating that infants are transitioning from having earlier abilities that appear more "universal," "broadly tuned," or "unconstrained" to having later abilities that appear more "specialized," "narrowly tuned," or "constrained." Perceptual narrowing, a well-known phenomenon related to face, speech, and…

  17. Effects of electrical conductivity of substrate materials on microstructure of diamond-like carbon films prepared by bipolar-type plasma based ion implantation

    NASA Astrophysics Data System (ADS)

    Nakao, S.; Sonoda, T.

    2013-03-01

    Diamond-like carbon (DLC) films are prepared by a bipolar-type plasma based ion implantation, and the structural differences between DLC films deposited on different electrical conductive substrates, i.e., conductive Si wafers and insulating glass plates are examined by Raman spectroscopy and x-ray photo emission spectroscopy (XPS). In the Raman measurements, graphite (G) and disorder (D) peaks are observed for both samples. However, the additional photo luminescence is overlapped on the spectra in the case of on-glass sample. To elucidate the structural difference, the intensity ratio of D to G peak (I(D)/I(G)), G peak position and full width at half maximum (FWHM) are obtained by curve fitting using Gaussian function and linear baseline. It is found that the I(D)/I(G) is lower, G peak position is higher and FWHM of G peak is narrower for on-glass sample than for on-Si sample. According to Robertson [1], lower I(D)/I(G) seems more sp3 C-C bonding in amount for on-glass sample. In contrast, higher G peak position and narrower FWHM of G peak suggest less sp3 C-C bonding in amount for on-glass sample. The results of XPS analysis with C1s spectra reveal that sp3 ratio, i.e., the intensity ratio of sp3/(sp3+sp2) is smaller for on-glass sample than for on-Si sample. The inconsistency of the trend between I(D)/I(G) and other parameters (G peak position and FWHM of G peak) might be caused by the overlap of photo luminescence signal on Raman spectrum as to on-glass sample. From these results, it is considered that sp3 C-C bonding is reduced in amount when using insulating substrate in comparison with conductive substrate.

  18. Methods and apparatuses using filter banks for multi-carrier spread-spectrum signals

    DOEpatents

    Moradi, Hussein; Farhang, Behrouz; Kutsche, Carl A

    2014-10-14

    A transmitter includes a synthesis filter bank to spread a data symbol to a plurality of frequencies by encoding the data symbol on each frequency, apply a common pulse-shaping filter, and apply gains to the frequencies such that a power level of each frequency is less than a noise level of other communication signals within the spectrum. Each frequency is modulated onto a different evenly spaced subcarrier. A demodulator in a receiver converts a radio frequency input to a spread-spectrum signal in a baseband. A matched filter filters the spread-spectrum signal with a common filter having characteristics matched to the synthesis filter bank in the transmitter by filtering each frequency to generate a sequence of narrow pulses. A carrier recovery unit generates control signals responsive to the sequence of narrow pulses suitable for generating a phase-locked loop between the demodulator, the matched filter, and the carrier recovery unit.

  19. Methods and apparatuses using filter banks for multi-carrier spread-spectrum signals

    DOEpatents

    Moradi, Hussein; Farhang, Behrouz; Kutsche, Carl A

    2014-05-20

    A transmitter includes a synthesis filter bank to spread a data symbol to a plurality of frequencies by encoding the data symbol on each frequency, apply a common pulse-shaping filter, and apply gains to the frequencies such that a power level of each frequency is less than a noise level of other communication signals within the spectrum. Each frequency is modulated onto a different evenly spaced subcarrier. A demodulator in a receiver converts a radio frequency input to a spread-spectrum signal in a baseband. A matched filter filters the spread-spectrum signal with a common filter having characteristics matched to the synthesis filter bank in the transmitter by filtering each frequency to generate a sequence of narrow pulses. A carrier recovery unit generates control signals responsive to the sequence of narrow pulses suitable for generating a phase-locked loop between the demodulator, the matched filter, and the carrier recovery unit.

  20. Methods and apparatuses using filter banks for multi-carrier spread spectrum signals

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Moradi, Hussein; Farhang, Behrouz; Kutsche, Carl A

    2017-01-31

    A transmitter includes a synthesis filter bank to spread a data symbol to a plurality of frequencies by encoding the data symbol on each frequency, apply a common pulse-shaping filter, and apply gains to the frequencies such that a power level of each frequency is less than a noise level of other communication signals within the spectrum. Each frequency is modulated onto a different evenly spaced subcarrier. A demodulator in a receiver converts a radio frequency input to a spread-spectrum signal in a baseband. A matched filter filters the spread-spectrum signal with a common filter having characteristics matched to themore » synthesis filter bank in the transmitter by filtering each frequency to generate a sequence of narrow pulses. A carrier recovery unit generates control signals responsive to the sequence of narrow pulses suitable for generating a phase-locked loop between the demodulator, the matched filter, and the carrier recovery unit.« less

  1. Methods and apparatuses using filter banks for multi-carrier spread spectrum signals

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Moradi, Hussein; Farhang, Behrouz; Kutsche, Carl A.

    2016-06-14

    A transmitter includes a synthesis filter bank to spread a data symbol to a plurality of frequencies by encoding the data symbol on each frequency, apply a common pulse-shaping filter, and apply gains to the frequencies such that a power level of each frequency is less than a noise level of other communication signals within the spectrum. Each frequency is modulated onto a different evenly spaced subcarrier. A demodulator in a receiver converts a radio frequency input to a spread-spectrum signal in a baseband. A matched filter filters the spread-spectrum signal with a common filter having characteristics matched to themore » synthesis filter bank in the transmitter by filtering each frequency to generate a sequence of narrow pulses. A carrier recovery unit generates control signals responsive to the sequence of narrow pulses suitable for generating a phase-locked loop between the demodulator, the matched filter, and the carrier recovery unit.« less

  2. 1/f Noise in Bak-Tang-Wiesenfeld Models on Narrow Stripes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Maslov, S.; Tang, C.; Zhang, Y.

    We report our findings of a 1/f power spectrum for the total amount of sand in directed and undirected Bak-Tang-Wiesenfeld models confined to narrow stripes and driven locally. The underlying mechanism for the 1/f noise in these systems is an exponentially long configuration memory giving rise to a very broad distribution of time scales. Both models are solved analytically with the help of an operator algebra to explicitly show the appearance of the long configuration memory. {copyright} {ital 1999} {ital The American Physical Society}

  3. Effect of Same-Temperature GaN Cap Layer on the InGaN/GaN Multiquantum Well of Green Light-Emitting Diode on Silicon Substrate

    PubMed Central

    Zheng, Changda; Wang, Li; Mo, Chunlan; Fang, Wenqing; Jiang, Fengyi

    2013-01-01

    GaN green LED was grown on Si (111) substrate by MOCVD. To enhance the quality of InGaN/GaN MQWs, same-temperature (ST) GaN protection layers with different thickness of 8 Å, 15 Å, and 30 Å were induced after the InGaN quantum wells (QWs) layer. Results show that a relative thicker cap layer is benefit to get InGaN QWs with higher In percent at fixed well temperature and obtain better QW/QB interface. As the cap thickness increases, the indium distribution becomes homogeneous as verified by fluorescence microscope (FLM). The interface of MQWs turns to be abrupt from XRD analysis. The intensity of photoluminescence (PL) spectrum is increased and the FWHM becomes narrow. PMID:24369453

  4. Effect of same-temperature GaN cap layer on the InGaN/GaN multiquantum well of green light-emitting diode on silicon substrate.

    PubMed

    Zheng, Changda; Wang, Li; Mo, Chunlan; Fang, Wenqing; Jiang, Fengyi

    2013-01-01

    GaN green LED was grown on Si (111) substrate by MOCVD. To enhance the quality of InGaN/GaN MQWs, same-temperature (ST) GaN protection layers with different thickness of 8 Å, 15 Å, and 30 Å were induced after the InGaN quantum wells (QWs) layer. Results show that a relative thicker cap layer is benefit to get InGaN QWs with higher In percent at fixed well temperature and obtain better QW/QB interface. As the cap thickness increases, the indium distribution becomes homogeneous as verified by fluorescence microscope (FLM). The interface of MQWs turns to be abrupt from XRD analysis. The intensity of photoluminescence (PL) spectrum is increased and the FWHM becomes narrow.

  5. A spectrum of an extrasolar planet.

    PubMed

    Richardson, L Jeremy; Deming, Drake; Horning, Karen; Seager, Sara; Harrington, Joseph

    2007-02-22

    Of the over 200 known extrasolar planets, 14 exhibit transits in front of their parent stars as seen from Earth. Spectroscopic observations of the transiting planets can probe the physical conditions of their atmospheres. One such technique can be used to derive the planetary spectrum by subtracting the stellar spectrum measured during eclipse (planet hidden behind star) from the combined-light spectrum measured outside eclipse (star + planet). Although several attempts have been made from Earth-based observatories, no spectrum has yet been measured for any of the established extrasolar planets. Here we report a measurement of the infrared spectrum (7.5-13.2 microm) of the transiting extrasolar planet HD 209458b. Our observations reveal a hot thermal continuum for the planetary spectrum, with an approximately constant ratio to the stellar flux over this wavelength range. Superposed on this continuum is a broad emission peak centred near 9.65 microm that we attribute to emission by silicate clouds. We also find a narrow, unidentified emission feature at 7.78 microm. Models of these 'hot Jupiter' planets predict a flux peak near 10 microm, where thermal emission from the deep atmosphere emerges relatively unimpeded by water absorption, but models dominated by water fit the observed spectrum poorly.

  6. Effect of narrow band nonuniformity on unsteady heat up of water vapor under radiation-conduction combined heat transfer

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Okamoto, Tatsuyuki; Tanaka, Tomohiro; Morimune, Atsushi

    Effect of narrow band nonuniformity on unsteady heat up process of water vapor under radiation-conduction combined heat transfer is examined by comparing the result of numerical simulations with and without incorporation of narrow band nonuniformity. The authors propose a rational and comprehensive computational approach for incorporating the narrow band nonuniformity into numerical simulations of radiative heat transfer when the considered field is nonisothermal. Results of examination exhibited that the contribution of radiative heat transfer to the heat up rate of water vapor may be almost twice overestimated, if the narrow band nonuniformity effect is neglected. Separate analyses of radiative energymore » attributed to wall emission and gas emission clarified that the absorption of wall emission is overestimated and, on the contrary, the absorption of radiation energy emitted by water vapor itself is underestimated if the narrow band nonuniformity is neglected. The reason why such over- or under-estimation is induced is understood by examining the influence of line overlap parameter on the transmittance averaged within a narrow band. Smaller value of line overlap parameter {gamma}/d means more violent narrow band nonuniformity. The broken lines show the narrow band transmittance for flat incident power spectrum, and the solid lines show that for the radiative emission from the absorbing gas itself. It is also clarified that the disregard of the narrow band nonuniformity give rise to serious error in the estimation of absorption rate of wall and gas emission even in the case where the disregard of narrow band nonuniformity bring little change to the temperature distribution. The results illustrated in this paper suggest that the narrow band nonuniformity should not be neglected.« less

  7. Unmasking tandem site interaction in human acetylcholinesterase. Substrate activation with a cationic acetanilide substrate.

    PubMed

    Johnson, Joseph L; Cusack, Bernadette; Davies, Matthew P; Fauq, Abdul; Rosenberry, Terrone L

    2003-05-13

    Acetylcholinesterase (AChE) contains a narrow and deep active site gorge with two sites of ligand binding, an acylation site (or A-site) at the base of the gorge, and a peripheral site (or P-site) near the gorge entrance. The P-site contributes to catalytic efficiency by transiently binding substrates on their way to the acylation site, where a short-lived acyl enzyme intermediate is produced. A conformational interaction between the A- and P-sites has recently been found to modulate ligand affinities. We now demonstrate that this interaction is of functional importance by showing that the acetylation rate constant of a substrate bound to the A-site is increased by a factor a when a second molecule of substrate binds to the P-site. This demonstration became feasible through the introduction of a new acetanilide substrate analogue of acetylcholine, 3-(acetamido)-N,N,N-trimethylanilinium (ATMA), for which a = 4. This substrate has a low acetylation rate constant and equilibrates with the catalytic site, allowing a tractable algebraic solution to the rate equation for substrate hydrolysis. ATMA affinities for the A- and P-sites deduced from the kinetic analysis were confirmed by fluorescence titration with thioflavin T as a reporter ligand. Values of a >1 give rise to a hydrolysis profile called substrate activation, and the AChE site-specific mutant W86F, and to a lesser extent wild-type human AChE itself, showed substrate activation with acetylthiocholine as the substrate. Substrate activation was incorporated into a previous catalytic scheme for AChE in which a bound P-site ligand can also block product dissociation from the A-site, and two additional features of the AChE catalytic pathway were revealed. First, the ability of a bound P-site ligand to increase the substrate acetylation rate constant varied with the structure of the ligand: thioflavin T accelerated ATMA acetylation by a factor a(2) of 1.3, while propidium failed to accelerate. Second, catalytic rate

  8. Simultaneous band-gap narrowing and carrier-lifetime prolongation of organic–inorganic trihalide perovskites

    PubMed Central

    Kong, Lingping; Liu, Gang; Gong, Jue; Hu, Qingyang; Schaller, Richard D.; Dera, Przemyslaw; Zhang, Dongzhou; Liu, Zhenxian; Yang, Wenge; Zhu, Kai; Tang, Yuzhao; Wang, Chuanyi; Wei, Su-Huai; Xu, Tao; Mao, Ho-kwang

    2016-01-01

    The organic–inorganic hybrid lead trihalide perovskites have been emerging as the most attractive photovoltaic materials. As regulated by Shockley–Queisser theory, a formidable materials science challenge for improvement to the next level requires further band-gap narrowing for broader absorption in solar spectrum, while retaining or even synergistically prolonging the carrier lifetime, a critical factor responsible for attaining the near-band-gap photovoltage. Herein, by applying controllable hydrostatic pressure, we have achieved unprecedented simultaneous enhancement in both band-gap narrowing and carrier-lifetime prolongation (up to 70% to ∼100% increase) under mild pressures at ∼0.3 GPa. The pressure-induced modulation on pure hybrid perovskites without introducing any adverse chemical or thermal effect clearly demonstrates the importance of band edges on the photon–electron interaction and maps a pioneering route toward a further increase in their photovoltaic performance. PMID:27444014

  9. Spectral narrowing of a 980 nm tapered diode laser bar

    NASA Astrophysics Data System (ADS)

    Vijayakumar, Deepak; Jensen, Ole Bjarlin; Lucas Leclin, Ga"lle; Petersen, Paul Michael; Thestrup, Birgitte

    2011-03-01

    High power diode laser bars are interesting in many applications such as solid state laser pumping, material processing, laser trapping, laser cooling and second harmonic generation. Often, the free running laser bars emit a broad spectrum of the order of several nanometres which limit their scope in wavelength specific applications and hence, it is vital to stabilize the emission spectrum of these devices. In our experiment, we describe the wavelength narrowing of a 12 element 980 nm tapered diode laser bar using a simple Littman configuration. The tapered laser bar which suffered from a big smile has been "smile corrected" using individual phase masks for each emitter. The external cavity consists of the laser bar, both fast and slow axis micro collimators, smile correcting phase mask, 6.5x beam expanding lens combination, a 1200 lines/mm reflecting grating with 85% efficiency in the first order, a slow axis focusing cylindrical lens of 40 mm focal length and an output coupler which is 10% reflective. In the free running mode, the laser emission spectrum was 5.5 nm wide at an operating current of 30A. The output power was measured to be in excess of 12W. Under the external cavity operation, the wavelength spread of the laser could be limited to 0.04 nm with an output power in excess of 8 W at an operating current of 30A. The spectrum was found to be tuneable in a range of 16 nm.

  10. The Effect of Sea Surface Slicks on the Doppler Spectrum Width of a Backscattered Microwave Signal.

    PubMed

    Karaev, Vladimir; Kanevsky, Mikhail; Meshkov, Eugeny

    2008-06-06

    The influence of a surface-active substance (SAS) film on the Doppler spectrum width at small incidence angles is theoretically investigated for the first time for microwave radars with narrow-beam and knife-beam antenna patterns. It is shown that the requirements specified for the antenna system depend on the radar motion velocity. A narrow-beam antenna pattern should be used to detect slicks by an immobile radar, whereas radar with a knife-beam antenna pattern is needed for diagnostics from a moving platform. The study has revealed that the slick contrast in the Doppler spectrum width increases as the radar wavelength diminishes, thus it is preferable to utilize wavelengths not larger than 2 cm for solving diagnostic problems. The contrast in the Doppler spectrum width is generally weaker than that in the radar backscattering cross section; however, spatial and temporal fluctuations of the Doppler spectrum width are much weaker than those of the reflected signal power. This enables one to consider the Doppler spectrum as a promising indicator of slicks on water surface.

  11. The X-ray spectrum and time variability of narrow emission line galaxies

    NASA Technical Reports Server (NTRS)

    Mushotzky, R.

    1981-01-01

    X-ray spectral and temporal observations are reported for six narrow emission line galaxies (NELGs), all of which are fitted by power-law X-ray spectra of energy slope 0.8 and have column densities in the line of sight greater than 1 x 10 to the 22nd atoms/sq cm. Three of the objects, NGC 526a, NGC 2110 and MCG-5-23-16 are variable in their X-ray flux, and the latter two, along with NGC 5506 and NGC 7582, showed detectable variability in at least one observation. The measured X-ray properties of these NELGs, which also included NGC 2992, strongly resemble those of previously-measured type 1 Seyferts of the same X-ray luminosity and lead to the conclusion of great similarity between the NELGs and low-luminosity type 1 Seyferts. The implications of these observations for the optical line-emitting region structure of these galaxies are discussed.

  12. Biochemistry students' ideas about how an enzyme interacts with a substrate.

    PubMed

    Linenberger, Kimberly J; Bretz, Stacey Lowery

    2015-01-01

    Enzyme-substrate interactions are a fundamental concept of biochemistry that is built upon throughout multiple biochemistry courses. Central to understanding enzyme-substrate interactions is specific knowledge of exactly how an enzyme and substrate interact. Within this narrower topic, students must understand the various binding sites on an enzyme and be able to reason from simplistic lock and key or induced fit models to the more complex energetics model of transition state theory. Learning to understand these many facets of enzyme-substrate interactions and reasoning from multiple models present challenges where students incorrectly make connections between concepts or make no connection at all. This study investigated biochemistry students' understanding of enzyme-substrate interactions through the use of clinical interviews and a national administration (N = 707) of the Enzyme-Substrate Interactions Concept Inventory. Findings include misconceptions regarding the nature of enzyme-substrate interactions, naïve ideas about the active site, a lack of energetically driven interactions, and an incomplete understanding of the specificity pocket. © 2015 by the International Union of Biochemistry and Molecular Biology.

  13. Narrow field electromagnetic sensor system and method

    DOEpatents

    McEwan, Thomas E.

    1996-01-01

    A narrow field electromagnetic sensor system and method of sensing a characteristic of an object provide the capability to realize a characteristic of an object such as density, thickness, or presence, for any desired coordinate position on the object. One application is imaging. The sensor can also be used as an obstruction detector or an electronic trip wire with a narrow field without the disadvantages of impaired performance when exposed to dirt, snow, rain, or sunlight. The sensor employs a transmitter for transmitting a sequence of electromagnetic signals in response to a transmit timing signal, a receiver for sampling only the initial direct RF path of the electromagnetic signal while excluding all other electromagnetic signals in response to a receive timing signal, and a signal processor for processing the sampled direct RF path electromagnetic signal and providing an indication of the characteristic of an object. Usually, the electromagnetic signal is a short RF burst and the obstruction must provide a substantially complete eclipse of the direct RF path. By employing time-of-flight techniques, a timing circuit controls the receiver to sample only the initial direct RF path of the electromagnetic signal while not sampling indirect path electromagnetic signals. The sensor system also incorporates circuitry for ultra-wideband spread spectrum operation that reduces interference to and from other RF services while allowing co-location of multiple electronic sensors without the need for frequency assignments.

  14. Narrow field electromagnetic sensor system and method

    DOEpatents

    McEwan, T.E.

    1996-11-19

    A narrow field electromagnetic sensor system and method of sensing a characteristic of an object provide the capability to realize a characteristic of an object such as density, thickness, or presence, for any desired coordinate position on the object. One application is imaging. The sensor can also be used as an obstruction detector or an electronic trip wire with a narrow field without the disadvantages of impaired performance when exposed to dirt, snow, rain, or sunlight. The sensor employs a transmitter for transmitting a sequence of electromagnetic signals in response to a transmit timing signal, a receiver for sampling only the initial direct RF path of the electromagnetic signal while excluding all other electromagnetic signals in response to a receive timing signal, and a signal processor for processing the sampled direct RF path electromagnetic signal and providing an indication of the characteristic of an object. Usually, the electromagnetic signal is a short RF burst and the obstruction must provide a substantially complete eclipse of the direct RF path. By employing time-of-flight techniques, a timing circuit controls the receiver to sample only the initial direct RF path of the electromagnetic signal while not sampling indirect path electromagnetic signals. The sensor system also incorporates circuitry for ultra-wideband spread spectrum operation that reduces interference to and from other RF services while allowing co-location of multiple electronic sensors without the need for frequency assignments. 12 figs.

  15. Optimization of the graphical method of Swanepoel for characterization of thin film on substrate specimens from their transmittance spectrum

    NASA Astrophysics Data System (ADS)

    Minkov, D. A.; Gavrilov, G. M.; Moreno, J. M. D.; Vazquez, C. G.; Marquez, E.

    2017-03-01

    The accuracy of the popular graphical method of Swanepoel (SGM) for the characterization of a thin film on a substrate specimen from its interference transmittance spectrum depends on the subjective choice of four characterization parameters: the slope of the graph, the order number for the longest wavelength extremum, and the two numbers of the extrema used for the calculation approximations of the average film thickness. Here, an error metric is introduced for estimating the accuracy of SGM characterization. An algorithm is proposed for the optimization of SGM, named the OGM algorithm, based on the minimization of this error metric. Its execution provides optimized values of the four characterization parameters, and the respective computation of the most accurate film characteristics achievable within the framework of SGM. Moreover, substrate absorption is accounted for, unlike in the classical SGM, which is beneficial when using modern UV/visible/NIR spectrophotometers due to the relatively larger amount of absorption in the commonly used glass substrates for wavelengths above 1700 nm. A significant increase in the accuracy of the film characteristics is obtained employing the OGM algorithm compared to the SGM algorithm for two model specimens. Such improvements in accuracy increase with increasing film absorption. The results of the film characterization by the OGM algorithm are presented for two specimens containing RF-magnetron-sputtered a-Si films with disparate film thicknesses. The computed average film thicknesses are within 1.1% of the respective film thicknesses measured by SEM for both films. Achieving such high film characterization accuracy is particularly significant for the film with a computed average thickness of 3934 nm, since we are not aware of any other film with such a large thickness that has been characterized by SGM.

  16. Research and design of an optical system of biochemical analyzer based on the narrow-band pass filter

    NASA Astrophysics Data System (ADS)

    Xiao, Ze-xin; Chen, Kuan

    2008-03-01

    Biochemical analyzer is one of the important instruments in the clinical diagnosis, and its optical system is the important component. The operation of this optical system can be regard as three parts. The first is transforms the duplicate colored light as the monochromatic light. The second is transforms the light signal of the monochromatic, which have the information of the measured sample, as the electric signal by use the photoelectric detector. And the last is to send the signal to data processing system by use the control system. Generally, there are three types monochromators: prism, optical grating and narrow-band pass filter. Thereinto, the narrow-band pass filter were widely used in the semi-auto biochemical analyzer. Through analysed the principle of biochemical analyzer base on the narrow-band pass filter, we known that the optical has three features. The first is the optical path of the optical system is a non- imaging system. The second, this system is wide spectrum region that contain visible light and ultraviolet spectrum. The third, this is a little aperture and little field monochromatic light system. Therefore, design idea of this optical system is: (1) luminous energy in the system less transmission loss; (2) detector coupled to the luminous energy efficient; mainly correct spherical aberration. Practice showed the point of Image quality evaluation: (1) dispersion circle diameter equal the receiving device pixel effective width of 125%, and the energy distribution should point target of 80% of energy into the receiving device pixel width of the effective diameter in this dispersion circle; (2) With MTF evaluation, the requirements in 20lp/ mm spatial frequency, the MTF values should not be lower than 0.6. The optical system should be fit in with ultraviolet and visible light width spectrum, and the detector image plane can but suited the majority visible light spectrum when by defocus optimization, and the image plane of violet and ultraviolet

  17. The Narrow-Line Region of Narrow-Line Seyfert 1 Galaxies

    NASA Astrophysics Data System (ADS)

    Rodríguez-Ardila, A.; Binette, Luc; Pastoriza, Miriani G.; Donzelli, Carlos J.

    2000-08-01

    This work studies the optical emission-line properties and physical conditions of the narrow-line region (NLR) of seven narrow-line Seyfert 1 galaxies (NLS1's) for which high signal-to-noise ratio spectroscopic observations were available. The resolution is 340 km s-1 (at Hα) over the wavelength interval 3700-9500 Å, enabling us to separate the broad and narrow components of the permitted emission lines. Our results show that the flux carried out by the narrow component of Hβ is, on average, 50% of the total line flux. As a result, the [O III] λ5007/Hβ ratio emitted in the NLR varies from 1 to 5, instead of the universally adopted value of 10. This has strong implications for the required spectral energy distribution that ionizes the NLR gas. Photoionization models that consider a NLR composed of a combination of matter-bounded and ionization-bounded clouds are successful at explaining the low [O III] λ5007/Hβ ratio and the weakness of low-ionization lines of NLS1's. Variation of the relative proportion of these two type of clouds nicely reproduces the dispersion of narrow-line ratios found among the NLS1 sample. Assuming similar physical model parameters of both NLS1's and the normal Seyfert 1 galaxy NGC 5548, we show that the observed differences of emission-line ratios between these two groups of galaxies can be explained, to a first approximation, in terms of the shape of the input ionizing continuum. Narrow emission-line ratios of NLS1's are better reproduced by a steep power-law continuum in the EUV-soft X-ray region, with spectral index α~-2. Flatter spectral indices (α~-1.5) match the observed line ratios of NGC 5548 but are unable to provide a good match to the NLS1 ratios. This result is consistent with ROSAT observations of NLS1's, which show that these objects are characterized by steeper power-law indices than those of Seyfert 1 galaxies with strong broad optical lines. Based on observations made at CASLEO. Complejo Astronómico El Leoncito

  18. Engineering the Frequency Spectrum of Bright Squeezed Vacuum via Group Velocity Dispersion in an SU(1,1) Interferometer.

    PubMed

    Lemieux, Samuel; Manceau, Mathieu; Sharapova, Polina R; Tikhonova, Olga V; Boyd, Robert W; Leuchs, Gerd; Chekhova, Maria V

    2016-10-28

    Bright squeezed vacuum, a promising tool for quantum information, can be generated by high-gain parametric down-conversion. However, its frequency and angular spectra are typically quite broad, which is undesirable for applications requiring single-mode radiation. We tailor the frequency spectrum of high-gain parametric down-conversion using an SU(1,1) interferometer consisting of two nonlinear crystals with a dispersive medium separating them. The dispersive medium allows us to select a narrow band of the frequency spectrum to be exponentially amplified by high-gain parametric amplification. The frequency spectrum is thereby narrowed from (56.5±0.1) to (1.22±0.02)  THz and, in doing so, the number of frequency modes is reduced from approximately 50 to 1.82±0.02. Moreover, this method provides control and flexibility over the spectrum of the generated light through the timing of the pump.

  19. Spectrally narrowed laserlike emission in a novel organic salt, DEST: cooperative emission

    NASA Astrophysics Data System (ADS)

    Tan, Shida; Mishra, Alpana; Ahyi, Ayayi; Bhowmik, Achintya; Dharmadhikari, Aditya; Thakur, Mrinal

    2001-03-01

    We have synthesized a novel organic salt, 4'-diethylamino-N-methyl-4-stilbazolium p-toluenesulfonate (DEST). Frequency-doubled pulses (55 ps) from a Nd:YAG laser at 10 Hz repetition rate were used to pump DEST solution in methanol and a 20% conversion efficiency in laserlike emission was observed without external mirrors. The low energy PL quantum efficiency of DEST is very low. The peak of the emission spectrum was at 617 nm and the threshold pump energy for spectral-narrowing was less than 1 μJ. Beyond the threshold, the FWHM of the spectrum was found to have reduced from 70 nm to 14 nm The characteristics are similar to that of another organic salt, SPCD^1, which has been recently reported. Cooperative emission appears to play a dominant role in this emission process. 1. A. K. Bhowmik, A. Dharmadhikari, and M. Thakur, OSA Technical Digest, 467, CLEO (1999).

  20. Review of measurements of the RF spectrum of radiation from lightning

    NASA Technical Reports Server (NTRS)

    Levine, D. M.

    1986-01-01

    Measurements reported in the literature of the spectrum of electromagnetic radiation from lightning in the frequency range from 1 kHz to 1 GHz are reviewed. Measurements have been made either by monitoring the power received at individual frequencies using a narrow bandwidth recording device tuned to the frequencies under investigation or by recording the transient (time dependent) radiation with a wide bandwidth device and then Fourier transforming the waveform to obtain a spectrum. Measurements of the first type were made extensively in the 1950's and 1960's and several composite spectra have been deduced by normalizing the data of different investigators to common units of bandwidth and distance. The composite spectra tend to peak near 5 kHz and then decrease roughly as (frequency) to the -1, up to nearly 100 MHz where scatter in the data make the behavior uncertain. Measurements of the second type have been reported for return strokes, the stepped leader and for some intracloud processes. The spectrum of first return strokes obtained in this manner is very similar to the composite spectra obtained from the narrow-band measurements.

  1. Segmented-spectrum detection mechanism for medical x-ray in CdTe

    NASA Astrophysics Data System (ADS)

    Shi, Zaifeng; Meng, Qingzhen; Cao, Qingjie; Yao, Suying

    2016-01-01

    This paper presents a segmented X-ray spectrum detection method based on a layered X-ray detector in Cadmium Telluride (CdTe) substrate. We describe the three-dimensional structure of proposed detector pixel and investigate the matched spectrum-resolving method. Polychromatic X-ray beam enter the CdTe substrate edge on and will be absorbed completely in different thickness varying with photon energy. Discrete potential wells are formed under external controlling voltage to collect the photo-electrons generated in different layers, and segmented X-ray spectrum can be deduced from the quantity of photo-electrons. In this work, we verify the feasibility of the segmented-spectrum detection mechanism by simulating the absorption of monochromatic X-ray in a CdTe substrate. Experiments in simulation show that the number of photo-electrons grow exponentially with the increase of incident thickness, and photons with different energy will be absorbed in various thickness. The charges generated in different layers are collected into adjacent potential wells, and collection efficiency is estimated to be about 87% for different incident intensity under the 40000V/cm electric field. Errors caused by charge sharing between neighboring layers are also analyzed, and it can be considered negligible by setting appropriate size of electrodes.

  2. Sky-radiance gradient measurements at narrow bands in the visible.

    PubMed

    Winter, E M; Metcalf, T W; Stotts, L B

    1995-07-01

    Accurate calibrated measurements of the radiance of the daytime sky were made in narrow bands in the visible portion of the spectrum. These measurements were made over several months and were tabulated in a sun-referenced coordinate system. The radiance as a function of wavelength at angles ranging from 5 to 90 deg was plotted. A best-fit inverse power-law fit shows inversely linear behavior of the radiance versus wavelength near the Sun (5 deg) and a slope approaching inverse fourth power far from the Sun (60 deg). This behavior fits a Mie-scattering interpretation near the Sun and a Rayleigh-scattering interpretation away from the Sun. The results are also compared with LOWTRAN models.

  3. Ultra narrow flat-top filter based on multiple equivalent phase shifts

    NASA Astrophysics Data System (ADS)

    Wang, Fei; Zou, Xihua; Yin, Zuowei; Chen, Xiangfei; Shen, Haisong

    2008-11-01

    Instead of real phase shifts, equivalent phase shifts (EPS) are adopted to construct ultra narrow phase-shifted band-pass filer in sampled Bragg gratings (SBG). Two optimized distributions of multiple equivalent phase shifts, using 2 and 5 EPSs respectively, are given in this paper to realize flat-top and ripple-free transmission characteristics simultaneously. Also two demonstrations with 5 EPSs both on hydrogen-loaded and photosensitive fibers are presented and their spectrums are examined by an optical vector analyzer (OVA). Given only ordinary phase mask and sub-micrometer precision control, ultra-narrowband flat-top filters with expected performance can be achieved flexibly and cost-effectively.

  4. Narrow band gap amorphous silicon semiconductors

    DOEpatents

    Madan, A.; Mahan, A.H.

    1985-01-10

    Disclosed is a narrow band gap amorphous silicon semiconductor comprising an alloy of amorphous silicon and a band gap narrowing element selected from the group consisting of Sn, Ge, and Pb, with an electron donor dopant selected from the group consisting of P, As, Sb, Bi and N. The process for producing the narrow band gap amorphous silicon semiconductor comprises the steps of forming an alloy comprising amorphous silicon and at least one of the aforesaid band gap narrowing elements in amount sufficient to narrow the band gap of the silicon semiconductor alloy below that of amorphous silicon, and also utilizing sufficient amounts of the aforesaid electron donor dopant to maintain the amorphous silicon alloy as an n-type semiconductor.

  5. [Study on the Spectral Characteristics of the Narrow-Band Filter in SHS].

    PubMed

    Luo, Hai-yan; Shi, Hai-liang; Li, Zhi-wei; Li, Shuang; Xiong, Wei; Hong, Jin

    2015-04-01

    The spectral response of spatial heterodyne spectroscopy (SHS) is determined by the spectrum property of narrow-band filter. As discussed in previous studies, the symmetric heterodyned interferogram of high frequency waves modulated by SHS and lack of sample lead to spectral confusion, which is associated with the true and ghost spectra. Because of the deviation from theoretical index of narrow-band filter in the process of coating, the boarded spectral response and middle wave shift are presented, and conditions in the theoretical Littrow wavelength made the effective wavelength range of SHS reduced. According to the measured curve of filter, a new wavenumber of zero spatial frequency can be reset by tunable laser, and it is easy for SHS to improve the spectral aliasing distortion. The results show that it is utilized to the maximum extent of the effective bandwidth by adjusting the grating angle of rotation to change the Littrow wavelength of the basic frequency, and the spectral region increased to 14.9 nm from original 12.9 nm.

  6. Widely tunable narrow-band coherent Terahertz radiation from an undulator at THU

    NASA Astrophysics Data System (ADS)

    Su, X.; Wang, D.; Tian, Q.; Liang, Y.; Niu, L.; Yan, L.; Du, Y.; Huang, W.; Tang, C.

    2018-01-01

    There is anxious demand for intense widely tunable narrow-band Terahertz (THz) radiation in scientific research, which is regarded as a powerful tool for the coherent control of matter. We report the generation of widely tunable THz radiation from a planar permanent magnet undulator at Tsinghua University (THU). A relativistic electron beam is compressed by a magnetic chicane into sub-ps bunch length to excite THz radiation in the undulator coherently. The THz frequency can be tuned from 0.4 THz to 10 THz continuously with narrow-band spectrums when the undulator gap ranges from 23 mm to 75 mm. The measured pulse THz radiation energy from 220 pC bunch is 3.5 μJ at 1 THz and tens of μJ pulse energy (corresponding peak power of 10 MW) can be obtained when excited by 1 nC beam extrapolated from the property of coherent radiation. The experimental results agree well with theoretical predictions, which demonstrates a suitable THz source for the many applications that require intense and widely tunable THz sources.

  7. LASER APPLICATIONS AND OTHER TOPICS IN QUANTUM ELECTRONICS: Measurement of the surface wavelength distribution of narrow-band radiation by a colorimetric method

    NASA Astrophysics Data System (ADS)

    Kraiskii, A. V.; Mironova, T. V.; Sultanov, T. T.

    2010-09-01

    A method is suggested for determining the wavelength of narrow-band light from a digital photograph of a radiating surface. The digital camera used should be appropriately calibrated. The accuracy of the wavelength measurement is better than 1 nm. The method was tested on the yellow doublet of mercury spectrum and on the adjacent continuum of the incandescent lamp radiation spectrum. By means of the method suggested the homogeneity of holographic sensor swelling was studied in stationary and transient cases.

  8. Voltage control of magnetism in NiZn ferrite/mica/PMNPT heterostructure with giant tunability and narrow linewidth

    NASA Astrophysics Data System (ADS)

    Wang, Xinjun; Chen, Yunpeng; Chen, Huaihao; Gao, Yuan; He, Yifan; Li, Menghui; Lin, Hwaider; Sun, Neville; Sun, Nian

    2018-05-01

    Recently, large magnetoelectric coupling of a spinel/piezoelectric heterostructure has been reported. However, the linewidth of the spinel is very large due to lattice mismatch when ferrite is directly deposited on piezoelectric substrates. This indicates a large magnetic loss, which impedes the spinel/piezoelectric heterostructure from useful device applications. Mica is a well-known 2D material, which can be split manually layer by layer without the substrate clamping effect. In this report, NiZn ferrite was deposited on a mica substrate by a spin-spray deposition technique. Spin-spray deposition is a wet chemical synthesis technique involving several chemical reactions for generating high-quality crystalline spinel ferrite films with various compositions directly from an aqueous solution. The thickness of ferrite is 2 μm, and the linewidth of the ferromagnetic resonance (FMR) is 115 Oe which is suitable for RF/microwave devices. The large FMR field tuning of 605 Oe was observed in NiZn ferrite/mica/PMN-PT heterostructures with minimal substrate clamping effect by reducing the thickness of the mica substrate. These multiferroic heterostructures exhibiting combined giant magnetoelectric coupling and narrow ferromagnetic resonance linewidth offer great opportunities for flexible RF magnetic devices.

  9. The ordinary life of the γ-ray emitting narrow-line Seyfert 1 galaxy PKS 1502+036

    DOE PAGES

    D'Ammando, F.; Orienti, M.; Doi, A.; ...

    2013-06-03

    In this paper, we report on multifrequency observations of the γ-ray emitting narrow-line Seyfert 1 galaxy PKS 1502+036 performed from radio to γ-rays during 2008 August–2012 November by Fermi-Large Area Telescope (LAT), Swift (X-ray Telescope and Ultraviolet/Optical Telescope), Owens Valley Radio Observatory, Very Long Baseline Array (VLBA) and Very Large Array. No significant variability has been observed in γ-rays, with 0.1–100 GeV flux that ranged between (3–7) × 10 –8 ph cm –2 s –1 using 3-month time bins. The photon index of the LAT spectrum (Γ = 2.60 ± 0.06) and the apparent isotropic γ-ray luminosity (L0.1-100 GeV =more » 7.8 × 10 45 erg s –1) over 51 months are typical of a flat spectrum radio quasar. The radio spectral variability and the one-sided structure, in addition to the observed γ-ray luminosity, suggest a relativistic jet with a high Doppler factor. In contrast to SBS 0846+513, the VLBA at 15 GHz did not observe superluminal motion for PKS 1502+036. Despite having the optical characteristics typical of a narrow-line Seyfert 1 galaxy, radio and γ-ray properties of PKS 1502+036 are found to be similar to those of a blazar at the low end of the black hole mass distribution for blazars. As a result, this is in agreement with what has been found in the case of the other γ-ray emitting narrow-line Seyfert 1 SBS 0846+513.« less

  10. The 1987 Whittier Narrows, California, earthquake: A Metropolitan shock

    NASA Astrophysics Data System (ADS)

    Hauksson, Egill; Stein, Ross S.

    1989-07-01

    Just 3 hours after the Whittier Narrows earthquake struck, it became clear that a heretofore unseen geological structure was seismically active beneath metropolitan Los Angeles. Contrary to initial expectations of strike-slip or oblique-slip motion on the Whittier fault, whose north end abuts the aftershock zone, the focal mechanism of the mainshock showed pure thrust faulting on a deep gently inclined surface [Hauksson et al., 1988]. This collection of nine research reports spans the spectrum of seismological, geodetic, and geological investigations carried out as a result of the Whittier Narrows earthquake. Although unseen, the structure was not unforeseen. Namson [1987] had published a retrodeformable geologic cross section (meaning that the sedimentary strata could be restored to their original depositional position) 100 km to the west of the future earthquake epicenter in which blind, or subsurface, thrust faults were interpreted to be active beneath the folded southern Transverse Ranges. Working 25 km to the west, Hauksson [1987] had also found a surprising number of microearthquakes with thrust focal mechanisms south of the Santa Monica mountains, another clue to a subsurface system of thrust faults. Finally, Davis [1987] had presented a preliminary cross section only 18 km to the west of Whittier Narrows that identified as "fault B" the thrust that would rupture later that year. Not only was the earthquake focus and its orientation compatible with the 10-15 km depth and north dipping orientation of Davis' proposed thrust, but fault B appears to continue beneath the northern flank of the Los Angeles basin, skirting within 5 km of downtown Los Angeles, an area of dense commercial high-rise building development. These results are refined and extended by Davis et al. [this issue].

  11. Composition-graded nanowire solar cells fabricated in a single process for spectrum-splitting photovoltaic systems.

    PubMed

    Caselli, Derek; Liu, Zhicheng; Shelhammer, David; Ning, Cun-Zheng

    2014-10-08

    Nanomaterials such as semiconductor nanowires have unique features that could enable novel optoelectronic applications such as novel solar cells. This paper aims to demonstrate one such recently proposed concept: Monolithically Integrated Laterally Arrayed Multiple Band gap (MILAMB) solar cells for spectrum-splitting photovoltaic systems. Two cells with different band gaps were fabricated simultaneously in the same process on a single substrate using spatially composition-graded CdSSe alloy nanowires grown by the Dual-Gradient Method in a chemical vapor deposition system. CdSSe nanowire ensemble devices tested under 1 sun AM1.5G illumination achieved open-circuit voltages up to 307 and 173 mV and short-circuit current densities as high as 0.091 and 0.974 mA/cm(2) for the CdS- and CdSe-rich cells, respectively. The open-circuit voltages were roughly three times those of similar CdSSe film cells fabricated for comparison due to the superior optical quality of the nanowires. I-V measurements were also performed using optical filters to simulate spectrum-splitting. The open-circuit voltages and fill factors of the CdS-rich subcells were uniformly larger than the corresponding CdSe-rich cells for similar photon flux, as expected. This suggests that if all wires can be contacted, the wide-gap cell is expected to have greater output power than the narrow-gap cell, which is the key to achieving high efficiencies with spectrum-splitting. This paper thus provides the first proof-of-concept demonstration of simultaneous fabrication of MILAMB solar cells. This approach to solar cell fabrication using single-crystal nanowires for spectrum-splitting photovoltaics could provide a future low-cost high-efficiency alternative to the conventional high-cost high-efficiency tandem cells.

  12. Observation of Five New Narrow Ω_{c}^{0} States Decaying to Ξ_{c}^{+}K^{-}.

    PubMed

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Bondar, A; Bondar, N; Bonivento, W; Bordyuzhin, I; Borgheresi, A; Borghi, S; Borisyak, M; Borsato, M; Bossu, F; Boubdir, M; Bowcock, T J V; Bowen, E; Bozzi, C; Braun, S; Britton, T; Brodzicka, J; Buchanan, E; Burr, C; Bursche, A; Buytaert, J; Cadeddu, S; Calabrese, R; Calvi, M; Calvo Gomez, M; Camboni, A; Campana, P; Campora Perez, D H; Capriotti, L; Carbone, A; Carboni, G; Cardinale, R; Cardini, A; Carniti, P; Carson, L; Carvalho Akiba, K; Casse, G; Cassina, L; Castillo Garcia, L; Cattaneo, M; Cavallero, G; Cenci, R; Chamont, D; Charles, M; Charpentier, Ph; Chatzikonstantinidis, G; Chefdeville, M; Chen, S; Cheung, S F; Chobanova, V; Chrzaszcz, M; Chubykin, A; Cid Vidal, X; Ciezarek, G; Clarke, P E L; Clemencic, M; Cliff, H V; Closier, J; Coco, V; Cogan, J; Cogneras, E; Cogoni, V; Cojocariu, L; Collins, P; Comerma-Montells, A; Contu, A; Cook, A; Coombs, G; Coquereau, S; Corti, G; Corvo, M; Costa Sobral, C M; Couturier, B; Cowan, G A; Craik, D C; Crocombe, A; Cruz Torres, M; Cunliffe, S; Currie, R; D'Ambrosio, C; Da Cunha Marinho, F; Dall'Occo, E; Dalseno, J; David, P N Y; Davis, A; De Bruyn, K; De Capua, S; De Cian, M; De Miranda, J M; De Paula, L; De Serio, M; De Simone, P; Dean, C T; Decamp, D; Deckenhoff, M; Del Buono, L; Dembinski, H-P; Demmer, M; Dendek, A; Derkach, D; Deschamps, O; Dettori, F; Dey, B; Di Canto, A; Di Nezza, P; Dijkstra, H; Dordei, F; Dorigo, M; Dosil Suárez, A; Dovbnya, A; Dreimanis, K; Dufour, L; Dujany, G; Dungs, K; Durante, P; Dzhelyadin, R; Dziewiecki, M; Dziurda, A; Dzyuba, A; Déléage, N; Easo, S; Ebert, M; Egede, U; Egorychev, V; Eidelman, S; Eisenhardt, S; Eitschberger, U; Ekelhof, R; Eklund, L; Ely, S; Esen, S; Evans, H M; Evans, T; Falabella, A; Farley, N; Farry, S; Fay, R; Fazzini, D; Ferguson, D; Fernandez, G; Fernandez Prieto, A; Ferrari, F; Ferreira Rodrigues, F; Ferro-Luzzi, M; Filippov, S; Fini, R A; Fiore, M; Fiorini, M; Firlej, M; Fitzpatrick, C; Fiutowski, T; Fleuret, F; Fohl, K; Fontana, M; Fontanelli, F; Forshaw, D C; Forty, R; Franco Lima, V; Frank, M; Frei, C; Fu, J; Funk, W; Furfaro, E; Färber, C; Gallas Torreira, A; Galli, D; Gallorini, S; Gambetta, S; Gandelman, M; Gandini, P; Gao, Y; Garcia Martin, L M; García Pardiñas, J; Garra Tico, J; Garrido, L; Garsed, P J; Gascon, D; Gaspar, C; Gavardi, L; Gazzoni, G; Gerick, D; Gersabeck, E; Gersabeck, M; Gershon, T; Ghez, Ph; Gianì, S; Gibson, V; Girard, O G; Giubega, L; Gizdov, K; Gligorov, V V; Golubkov, D; Golutvin, A; Gomes, A; Gorelov, I V; Gotti, C; Govorkova, E; Graciani Diaz, R; Granado Cardoso, L A; Graugés, E; Graverini, E; Graziani, G; Grecu, A; Greim, R; Griffith, P; Grillo, L; Gruberg Cazon, B R; Grünberg, O; Gushchin, E; Guz, Yu; Gys, T; Göbel, C; Hadavizadeh, T; Hadjivasiliou, C; Haefeli, G; Haen, C; Haines, S C; Hamilton, B; Han, X; Hansmann-Menzemer, S; Harnew, N; Harnew, S T; Harrison, J; Hatch, M; He, J; Head, T; Heister, A; Hennessy, K; Henrard, P; Henry, L; van Herwijnen, E; Heß, M; Hicheur, A; Hill, D; Hombach, C; Hopchev, P H; Huard, Z-C; Hulsbergen, W; Humair, T; Hushchyn, M; Hutchcroft, D; Idzik, M; Ilten, P; Jacobsson, R; Jalocha, J; Jans, E; Jawahery, A; Jiang, F; John, M; Johnson, D; Jones, C R; Joram, C; Jost, B; Jurik, N; Kandybei, S; Karacson, M; Kariuki, J M; Karodia, S; Kecke, M; Kelsey, M; Kenzie, M; Ketel, T; Khairullin, E; Khanji, B; Khurewathanakul, C; Kirn, T; Klaver, S; Klimaszewski, K; Klimkovich, T; Koliiev, S; Kolpin, M; Komarov, I; Kopecna, R; Koppenburg, P; Kosmyntseva, A; Kotriakhova, S; Kozachuk, A; Kozeiha, M; Kravchuk, L; Kreps, M; Krokovny, P; Kruse, F; Krzemien, W; Kucewicz, W; Kucharczyk, M; Kudryavtsev, V; Kuonen, A K; Kurek, K; Kvaratskheliya, T; Lacarrere, D; Lafferty, G; Lai, A; Lanfranchi, G; Langenbruch, C; Latham, T; Lazzeroni, C; Le Gac, R; van Leerdam, J; Leflat, A; Lefrançois, J; Lefèvre, R; Lemaitre, F; Lemos Cid, E; Leroy, O; Lesiak, T; Leverington, B; Li, T; Li, Y; Li, Z; Likhomanenko, T; Lindner, R; Lionetto, F; Liu, X; Loh, D; Longstaff, I; Lopes, J H; Lucchesi, D; Lucio Martinez, M; Luo, H; Lupato, A; Luppi, E; Lupton, O; Lusiani, A; Lyu, X; Machefert, F; Maciuc, F; Maev, O; Maguire, K; Malde, S; Malinin, A; Maltsev, T; Manca, G; Mancinelli, G; Manning, P; Maratas, J; Marchand, J F; Marconi, U; Marin Benito, C; Marinangeli, M; Marino, P; Marks, J; Martellotti, G; Martin, M; Martinelli, M; Martinez Santos, D; Martinez Vidal, F; Martins Tostes, D; Massacrier, L M; Massafferri, A; Matev, R; Mathad, A; Mathe, Z; Matteuzzi, C; Mauri, A; Maurice, E; Maurin, B; Mazurov, A; McCann, M; McNab, A; McNulty, R; Meadows, B; Meier, F; Melnychuk, D; Merk, M; Merli, A; Michielin, E; Milanes, D A; Minard, M-N; Mitzel, D S; Mogini, A; Molina Rodriguez, J; Monroy, I A; Monteil, S; Morandin, M; Morello, M J; Morgunova, O; Moron, J; Morris, A B; Mountain, R; Muheim, F; Mulder, M; Mussini, M; Müller, D; Müller, J; Müller, K; Müller, V; Naik, P; Nakada, T; Nandakumar, R; Nandi, A; Nasteva, I; Needham, M; Neri, N; Neubert, S; Neufeld, N; Neuner, M; Nguyen, T D; Nguyen-Mau, C; Nieswand, S; Niet, R; Nikitin, N; Nikodem, T; Nogay, A; Novoselov, A; O'Hanlon, D P; Oblakowska-Mucha, A; Obraztsov, V; Ogilvy, S; Oldeman, R; Onderwater, C J G; Otalora Goicochea, J M; Owen, P; Oyanguren, A; Pais, P R; Palano, A; Palutan, M; Papanestis, A; Pappagallo, M; Pappalardo, L L; Pappenheimer, C; Parker, W; Parkes, C; Passaleva, G; Pastore, A; Patel, M; Patrignani, C; Pearce, A; Pellegrino, A; Penso, G; Pepe Altarelli, M; Perazzini, S; Perret, P; Pescatore, L; Petridis, K; Petrolini, A; Petrov, A; Petruzzo, M; Picatoste Olloqui, E; Pietrzyk, B; Pikies, M; Pinci, D; Pistone, A; Piucci, A; Placinta, V; Playfer, S; Plo Casasus, M; Poikela, T; Polci, F; Poli Lener, M; Poluektov, A; Polyakov, I; Polycarpo, E; Pomery, G J; Ponce, S; Popov, A; Popov, D; Popovici, B; Poslavskii, S; Potterat, C; Price, E; Prisciandaro, J; Prouve, C; Pugatch, V; Puig Navarro, A; Punzi, G; Qian, C; Qian, W; Quagliani, R; Rachwal, B; Rademacker, J H; Rama, M; Ramos Pernas, M; Rangel, M S; Raniuk, I; Ratnikov, F; Raven, G; Redi, F; Reichert, S; Dos Reis, A C; Remon Alepuz, C; Renaudin, V; Ricciardi, S; Richards, S; Rihl, M; Rinnert, K; Rives Molina, V; Robbe, P; Rodrigues, A B; Rodrigues, E; Rodriguez Lopez, J A; Rodriguez Perez, P; Rogozhnikov, A; Roiser, S; Rollings, A; Romanovskiy, V; Romero Vidal, A; Ronayne, J W; Rotondo, M; Rudolph, M S; Ruf, T; Ruiz Valls, P; Saborido Silva, J J; Sadykhov, E; Sagidova, N; Saitta, B; Salustino Guimaraes, V; Sanchez Gonzalo, D; Sanchez Mayordomo, C; Sanmartin Sedes, B; Santacesaria, R; Santamarina Rios, C; Santimaria, M; Santovetti, E; Sarti, A; Satriano, C; Satta, A; Saunders, D M; Savrina, D; Schael, S; Schellenberg, M; Schiller, M; Schindler, H; Schlupp, M; Schmelling, M; Schmelzer, T; Schmidt, B; Schneider, O; Schopper, A; Schreiner, H F; Schubert, K; Schubiger, M; Schune, M-H; Schwemmer, R; Sciascia, B; Sciubba, A; Semennikov, A; Sergi, A; Serra, N; Serrano, J; Sestini, L; Seyfert, P; Shapkin, M; Shapoval, I; Shcheglov, Y; Shears, T; Shekhtman, L; Shevchenko, V; Siddi, B G; Silva Coutinho, R; Silva de Oliveira, L; Simi, G; Simone, S; Sirendi, M; Skidmore, N; Skwarnicki, T; Smith, E; Smith, I T; Smith, J; Smith, M; Soares Lavra, L; Sokoloff, M D; Soler, F J P; Souza De Paula, B; Spaan, B; Spradlin, P; Sridharan, S; Stagni, F; Stahl, M; Stahl, S; Stefko, P; Stefkova, S; Steinkamp, O; Stemmle, S; Stenyakin, O; Stevens, H; Stoica, S; Stone, S; Storaci, B; Stracka, S; Stramaglia, M E; Straticiuc, M; Straumann, U; Sun, L; Sutcliffe, W; Swientek, K; Syropoulos, V; Szczekowski, M; Szumlak, T; T'Jampens, S; Tayduganov, A; Tekampe, T; Tellarini, G; Teubert, F; Thomas, E; van Tilburg, J; Tilley, M J; Tisserand, V; Tobin, M; Tolk, S; Tomassetti, L; Tonelli, D; Topp-Joergensen, S; Toriello, F; Tourinho Jadallah Aoude, R; Tournefier, E; Tourneur, S; Trabelsi, K; Traill, M; Tran, M T; Tresch, M; Trisovic, A; Tsaregorodtsev, A; Tsopelas, P; Tully, A; Tuning, N; Ukleja, A; Ustyuzhanin, A; Uwer, U; Vacca, C; Vagnoni, V; Valassi, A; Valat, S; Valenti, G; Vazquez Gomez, R; Vazquez Regueiro, P; Vecchi, S; van Veghel, M; Velthuis, J J; Veltri, M; Veneziano, G; Venkateswaran, A; Verlage, T A; Vernet, M; Vesterinen, M; Viana Barbosa, J V; Viaud, B; Vieira, D; Vieites Diaz, M; Viemann, H; Vilasis-Cardona, X; Vitti, M; Volkov, V; Vollhardt, A; Voneki, B; Vorobyev, A; Vorobyev, V; Voß, C; de Vries, J A; Vázquez Sierra, C; Waldi, R; Wallace, C; Wallace, R; Walsh, J; Wang, J; Ward, D R; Wark, H M; Watson, N K; Websdale, D; Weiden, A; Whitehead, M; Wicht, J; Wilkinson, G; Wilkinson, M; Williams, M; Williams, M P; Williams, M; Williams, T; Wilson, F F; Wimberley, J; Winn, M A; Wishahi, J; Wislicki, W; Witek, M; Wormser, G; Wotton, S A; Wraight, K; Wyllie, K; Xie, Y; Xing, Z; Xu, Z; Yang, Z; Yang, Z; Yao, Y; Yin, H; Yu, J; Yuan, X; Yushchenko, O; Zarebski, K A; Zavertyaev, M; Zhang, L; Zhang, Y; Zhelezov, A; Zheng, Y; Zhu, X; Zhukov, V; Zucchelli, S

    2017-05-05

    The Ξ_{c}^{+}K^{-} mass spectrum is studied with a sample of pp collision data corresponding to an integrated luminosity of 3.3  fb^{-1}, collected by the LHCb experiment. The Ξ_{c}^{+} is reconstructed in the decay mode pK^{-}π^{+}. Five new, narrow excited Ω_{c}^{0} states are observed: the Ω_{c}(3000)^{0}, Ω_{c}(3050)^{0}, Ω_{c}(3066)^{0}, Ω_{c}(3090)^{0}, and Ω_{c}(3119)^{0}. Measurements of their masses and widths are reported.

  13. Lasing characteristics of InAs quantum dot laers on InP substrate

    NASA Technical Reports Server (NTRS)

    Yang, Y.; Qiu, D.; Uhl, R.; Chacon, R.

    2003-01-01

    Single-stack InAs self-assembled quantum dots (QD) lasers based on InP substrate have been grown by metalorganic vapor phase epitaxy. The narrow ridge waveguide lasers lased up to 260 K in continuous wave operation, and near room temperature in pulsed mode, with wavelengths between 1.59 to 1.74 mu m.

  14. Narrow bandpass steep edge optical filter for the JAST/T80 telescope instrumentation

    NASA Astrophysics Data System (ADS)

    Reichel, S.; Brauneck, U.; Bourquin, S.; Marín-Franch, A.

    2013-09-01

    The Observatorio Astrofisico de Javalambre in Spain observes with its JAST/T80 telescope galaxies in the Local Universe in a systematic study. This is accomplished with a multi-band photometric all sky survey called Javalambre Photometric Local Universe Survey (J-PLUS). A wide field camera receives the signals from universe via optical filters. In this presentation the development and design of a narrow bandpass steep edge filter with wide suppression will be shown. The filter has a full width half maximum in the range of 13-15 nm (with <1 nm tolerance) with central wavelengths in the range 350-860nm and an average transmission larger than 90% in the passband. Signals beyond the passband (blocking range) have to be suppressed down to 250nm and up to 1050nm (spectral regime), where a blocking of OD 5 (transmission < 10-5) is required. The edges have to be steep for a small transition width from 5% to 80%. The spectral requirements result in a large number of layers which are deposited with magnetron sputtering. The transmitted wavefront error of the optical filter must be less than lambda/2 over the 100mm aperture and the central wavelength uniformity must be better than +/- 0.4% over the clear aperture. The filter consists of optical filter glass and a coated substrate in order to reach the spectral requirements. The substrate is coated with more than 120 layers. The total filter thickness was specified to be 8.0mm. Results of steep edge narrow bandpass filters will be demonstrated fulfilling all these demanding requirements.

  15. Two Active States of the Narrow-Line Gamma-Ray-Loud AGN GB 1310 + 487

    NASA Technical Reports Server (NTRS)

    Sokolovsky, K. V.; Schinzel, F. K.; Tanaka, Y. T.; Abolmasov, P. K.; Angelakis, E.; Bulgarelli, A.; Carrasco, L.; Cenko, S. B.; Cheung, C. C.; Clubb, K. I.; hide

    2014-01-01

    Context. Previously unremarkable, the extragalactic radio source GB1310 487 showed gamma-ray flare on 2009 November 18, reaching a daily flux of approximately 10(exp -6) photons cm(exp -2) s(exp -1) at energies E greater than 100MeV and became one of the brightest GeV sources for about two weeks. Its optical spectrum shows strong forbidden-line emission while lacking broad permitted lines, which is not typical for a blazar. Instead, the spectrum resembles those of narrow emission-line galaxies. Aims. We investigate changes in the object's radio-to-GeV spectral energy distribution (SED) during and after the prominent gamma-ray flare with the aim of determining the nature of the object and of constraining the origin of the variable high-energy emission. Methods. The data collected by the Fermi and AGILE satellites at gamma-ray energies; Swift at X-ray and ultraviolet (UV); the Kanata, NOT, and Keck telescopes at optical; OAGH and WISE at infrared (IR); and IRAM30m, OVRO 40m, Effelsberg 100m, RATAN-600, and VLBA at radio are analyzed together to trace the SED evolution on timescales of months. Results. The gamma-ray radio-loud narrow-line active galactic nucleus (AGN) is located at redshift z = 0.638. It shines through an unrelated foreground galaxy at z = 0.500. The AGN light is probably amplified by gravitational lensing. The AGN SED shows a two-humped structure typical of blazars and gamma-ray-loud narrow-line Seyfert 1 galaxies, with the high-energy (inverse-Compton) emission dominating by more than an order of magnitude over the low-energy (synchrotron) emission during gamma-ray flares. The difference between the two SED humps is smaller during the low-activity state. Fermi observations reveal a strong correlation between the gamma-ray flux and spectral index, with the hardest spectrum observed during the brightest gamma-ray state. The gamma-ray flares occurred before and during a slow rising trend in the radio, but no direct association between gamma-ray and

  16. Two active states of the narrow-line gamma-ray-loud AGN GB 1310+487

    DOE PAGES

    Sokolovsky, K. V.

    2014-04-28

    Context. Previously unremarkable, the extragalactic radio source GB1310+487 showed a γ-ray flare on 2009 November 18, reaching a daily flux of ~ 10 -6 photons cm -2 s -1 at energies E > 100MeV and became one of the brightest GeV sources for about two weeks. Its optical spectrum shows strong forbidden-line emission while lacking broad permitted lines, which is not typical for a blazar. Instead, the spectrum resembles those of narrow emission-line galaxies. Aims. We investigate changes in the object’s radio-to-GeV spectral energy distribution (SED) during and after the prominent γ-ray flare with the aim of determining the naturemore » of the object and of constraining the origin of the variable high-energy emission. Methods. The data collected by the Fermi and AGILE satellites at γ-ray energies; Swift at X-ray and ultraviolet (UV); the Kanata, NOT, and Keck telescopes at optical; OAGH andWISE at infrared (IR); and IRAM30m, OVRO 40m, Effelsberg 100m, RATAN-600, and VLBA at radio are analyzed together to trace the SED evolution on timescales of months. Results. The γ-ray/radio-loud narrow-line active galactic nucleus (AGN) is located at redshift z = 0.638. It shines through an unrelated foreground galaxy at z = 0.500. The AGN light is probably amplified by gravitational lensing. The AGN SED shows a two-humped structure typical of blazars and γ-ray-loud narrow-line Seyfert 1 galaxies, with the high-energy (inverse-Compton) emission dominating by more than an order of magnitude over the low-energy (synchrotron) emission during γ-ray flares. The difference between the two SED humps is smaller during the low-activity state. Fermi observations reveal a strong correlation between the γ-ray flux and spectral index, with the hardest spectrum observed during the brightest γ-ray state. The γ-ray flares occurred before and during a slow rising trend in the radio, but no direct association between γ-ray and radio flares could be established. Conclusions. If the

  17. Ultra-narrow-linewidth erbium-doped lasers on a silicon photonics platform

    NASA Astrophysics Data System (ADS)

    Li, Nanxi; Purnawirman, Purnawirman; Magden, E. Salih; Singh, Gurpreet; Singh, Neetesh; Baldycheva, Anna; Hosseini, Ehsan S.; Sun, Jie; Moresco, Michele; Adam, Thomas N.; Leake, Gerald; Coolbaugh, Douglas; Bradley, Jonathan D. B.; Watts, Michael R.

    2018-02-01

    We report ultra-narrow-linewidth erbium-doped aluminum oxide (Al2O3:Er3+) distributed feedback (DFB) lasers with a wavelength-insensitive silicon-compatible waveguide design. The waveguide consists of five silicon nitride (SiNx) segments buried under silicon dioxide (SiO2) with a layer Al2O3:Er3+ deposited on top. This design has a high confinement factor (> 85%) and a near perfect (> 98%) intensity overlap for an octave-spanning range across near infrared wavelengths (950-2000 nm). We compare the performance of DFB lasers in discrete quarter phase shifted (QPS) cavity and distributed phase shifted (DPS) cavity. Using QPS-DFB configuration, we obtain maximum output powers of 0.41 mW, 0.76 mW, and 0.47 mW at widely spaced wavelengths within both the C and L bands of the erbium gain spectrum (1536 nm, 1566 nm, and 1596 nm). In a DPS cavity, we achieve an order of magnitude improvement in maximum output power (5.43 mW) and a side mode suppression ratio (SMSR) of > 59.4 dB at an emission wavelength of 1565 nm. We observe an ultra-narrow linewidth of ΔνDPS = 5.3 +/- 0.3 kHz for the DPS-DFB laser, as compared to ΔγQPS = 30.4 +/- 1.1 kHz for the QPS-DFB laser, measured by a recirculating self-heterodyne delayed interferometer (RSHDI). Even narrower linewidth can be achieved by mechanical stabilization of the setup, increasing the pump absorption efficiency, increasing the output power, or enhancing the cavity Q.

  18. A Multimodal Approach to Emotion Recognition Ability in Autism Spectrum Disorders

    ERIC Educational Resources Information Center

    Jones, Catherine R. G.; Pickles, Andrew; Falcaro, Milena; Marsden, Anita J. S.; Happe, Francesca; Scott, Sophie K.; Sauter, Disa; Tregay, Jenifer; Phillips, Rebecca J.; Baird, Gillian; Simonoff, Emily; Charman, Tony

    2011-01-01

    Background: Autism spectrum disorders (ASD) are characterised by social and communication difficulties in day-to-day life, including problems in recognising emotions. However, experimental investigations of emotion recognition ability in ASD have been equivocal, hampered by small sample sizes, narrow IQ range and over-focus on the visual modality.…

  19. Efficacy and Safety of Sarecycline, a Novel, Once-Daily, Narrow Spectrum Antibiotic for the Treatment of Moderate to Severe Facial Acne Vulgaris: Results of a Phase 2, Dose-Ranging Study.

    PubMed

    Leyden, James J; Sniukiene, Vilma; Berk, David R; Kaoukhov, Alexandre

    2018-03-01

    There is a need for new oral antibiotics for acne with improved safety profiles and targeted antibacterial spectra. Sarecycline is a novel, tetracycline-class antibiotic specifically designed for acne, offering a narrow spectrum of activity compared with currently available tetracyclines, including less activity against enteric Gram-negative bacteria. This phase 2 study evaluated the efficacy and safety of three doses of sarecycline for moderate to severe facial acne vulgaris. In this multicenter, double-blind, placebo-controlled study, patients aged 12 to 45 years were randomized to once-daily sarecycline 0.75 mg/kg, 1.5 mg/kg, 3.0 mg/kg, or placebo. Efficacy analyses included change from baseline in inflammatory and noninflammatory lesion counts at week 12, with between-group comparisons using analysis of covariance. Safety assessments included adverse events (AEs), clinical laboratories, vital signs, electrocardiograms, and physical examinations. Overall, 285 randomized patients received at least one dose of study drug. At week 12, sarecycline 1.5 mg/kg and 3.0 mg/kg groups demonstrated significantly reduced inflammatory lesions from baseline (52.7% and 51.8%, respectively) versus placebo (38.3%; P=0.02 and P=0.03, respectively). Sarecycline was safe and well tolerated, with similar gastrointestinal AE rates in sarecycline and placebo groups. Vertigo and photosensitivity AEs occurred in less than 1% of patients when pooling sarecycline groups; no vulvovaginal candidiasis AEs occurred. Discontinuation rates due to AEs were low. No serious AEs occurred. Once-daily sarecycline 1.5 mg/kg significantly reduced inflammatory lesions versus placebo and was safe and well tolerated with low rates of AEs, including gastrointestinal AEs. Sarecycline 3.0 mg/kg did not result in additional efficacy versus 1.5 mg/kg. Sarecycline may represent a novel, once-daily treatment for patients with moderate to severe acne. It offers a narrow antibacterial spectrum relative to other

  20. Affective neural response to restricted interests in autism spectrum disorders.

    PubMed

    Cascio, Carissa J; Foss-Feig, Jennifer H; Heacock, Jessica; Schauder, Kimberly B; Loring, Whitney A; Rogers, Baxter P; Pryweller, Jennifer R; Newsom, Cassandra R; Cockhren, Jurnell; Cao, Aize; Bolton, Scott

    2014-01-01

    Restricted interests are a class of repetitive behavior in autism spectrum disorders (ASD) whose intensity and narrow focus often contribute to significant interference with daily functioning. While numerous neuroimaging studies have investigated executive circuits as putative neural substrates of repetitive behavior, recent work implicates affective neural circuits in restricted interests. We sought to explore the role of affective neural circuits and determine how restricted interests are distinguished from hobbies or interests in typical development. We compared a group of children with ASD to a typically developing (TD) group of children with strong interests or hobbies, employing parent report, an operant behavioral task, and functional imaging with personalized stimuli based on individual interests. While performance on the operant task was similar between the two groups, parent report of intensity and interference of interests was significantly higher in the ASD group. Both the ASD and TD groups showed increased BOLD response in widespread affective neural regions to the pictures of their own interest. When viewing pictures of other children's interests, the TD group showed a similar pattern, whereas BOLD response in the ASD group was much more limited. Increased BOLD response in the insula and anterior cingulate cortex distinguished the ASD from the TD group, and parent report of the intensity and interference with daily life of the child's restricted interest predicted insula response. While affective neural network response and operant behavior are comparable in typical and restricted interests, the narrowness of focus that clinically distinguishes restricted interests in ASD is reflected in more interference in daily life and aberrantly enhanced insula and anterior cingulate response to individuals' own interests in the ASD group. These results further support the involvement of affective neural networks in repetitive behaviors in ASD. © 2013 The

  1. Affective neural response to restricted interests in Autism Spectrum Disorders

    PubMed Central

    Cascio, Carissa J.; Foss-Feig, Jennifer H.; Heacock, Jessica; Schauder, Kimberly B.; Loring, Whitney A.; Rogers, Baxter P.; Pryweller, Jennifer R.; Newsom, Cassandra R.; Cockhren, Jurnell; Cao, Aize; Bolton, Scott

    2013-01-01

    Background Restricted interests are a class of repetitive behavior in autism spectrum disorders (ASD) whose intensity and narrow focus often contribute to significant interference with daily functioning. While numerous neuroimaging studies have investigated executive circuits as putative neural substrates of repetitive behavior, recent work implicates affective neural circuits in restricted interests. We sought to explore the role of affective neural circuits and determine how restricted interests are distinguished from hobbies or interests in typical development. Methods We compared a group of children with ASD to a typically developing (TD) group of children with strong interests or hobbies, employing parent report, an operant behavioral task, and functional imaging with personalized stimuli based on individual interests. Results While performance on the operant task was similar between the two groups, parent report of intensity and interference of interests was significantly higher in the ASD group. Both the ASD and TD groups showed increased BOLD response in widespread affective neural regions to pictures of their own interest. When viewing pictures of other children's interests, the TD group showed a similar pattern, whereas BOLD response in the ASD group was much more limited. Increased BOLD response in the insula and anterior cingulate cortex distinguished the ASD from the TD group, and parent report of the intensity and interference with daily life of the child's restricted interest predicted insula response. Conclusions While affective neural network response and operant behavior are comparable in typical and restricted interests, the narrowness of focus that clinically distinguishes restricted interests in ASD is reflected in more interference in daily life and aberrantly enhanced insula and anterior cingulate response to individuals’ own interests in the ASD group. These results further support the involvement of affective neural networks in repetitive

  2. A filterless, visible-blind, narrow-band, and near-infrared photodetector with a gain

    NASA Astrophysics Data System (ADS)

    Shen, Liang; Zhang, Yang; Bai, Yang; Zheng, Xiaopeng; Wang, Qi; Huang, Jinsong

    2016-06-01

    In many applications of near-infrared (NIR) light detection, a band-pass filter is needed to exclude the noise caused by visible light. Here, we demonstrate a filterless, visible-blind, narrow-band NIR photodetector with a full-width at half-maximum of <50 nm for the response spectrum. These devices have a thick (>4 μm) nanocomposite absorbing layers made of polymer-fullerene:lead sulfide (PbS) quantum dots (QDs). The PbS QDs yield a photoconductive gain due to their hole-trapping effect, which effectively enhances both the responsivity and the visible rejection ratio of the external quantum efficiency by >10 fold compared to those without PbS QDs. Encouragingly, the inclusion of the PbS QDs does not increase the device noise. We directly measured a noise equivalent power (NEP) of 6.1 pW cm-2 at 890 nm, and a large linear dynamic range (LDR) over 11 orders of magnitude. The highly sensitive visible-blind NIR narrow-band photodetectors may find applications in biomedical engineering.

  3. Fermi monitoring of radio-loud narrow-line Seyfert 1 galaxies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Paliya, Vaidehi S.; Stalin, C. S.; Ravikumar, C. D., E-mail: vaidehi@iiap.res.in

    2015-02-01

    We present detailed analysis of the γ-ray flux variability and spectral properties of the five radio-loud narrow line Seyfert 1 (RL-NLSy1) galaxies, detected by the Large Area Telescope on board the Fermi Gamma-Ray Space Telescope, namely 1H 0323+342, SBS 0846+513, PMN J0948+0022, PKS 1502+036, and PKS 2004−447. The first three sources show significant flux variations, including the rapid variability of a few hours by 1H 0323+342. The average γ-ray spectrum of 1H 0323+342 and PMN J0948+0022 shows deviation from a simple power-law (PL) behavior, whereas the PL model gives a better fit for the other three sources. The spectra ofmore » 1H 0323+342, SBS 0846+513, and PMN J0948+0022, which are in low, flaring, and moderately active states, respectively, show significant curvature. Such curvature in the γ-ray spectrum of 1H 0323+342 and PMN J0948+0022 could be due to the emission region located inside the broad line region (BLR) where the primary mechanism of the γ-ray emission is inverse-Compton (IC) scattering of BLR photons occurring in the Klein–Nishina regime. The γ-ray emission of SBS 0846+513 is explained by IC scattering of dusty torus photons, which puts the emission region outside the BLR and thus under the Thomson regime. Therefore, the observed curvature of SBS 0846+513 could be intrinsic to the particle energy distribution. The presence of curvature in the γ-ray spectrum and flux variability amplitudes of some of the RL-NLSy1 galaxies suggests that these sources could be akin to low/moderate jet power flat spectrum radio quasars.« less

  4. A terrain based simulation system to predict the interference caused by networks of spread spectrum systems

    NASA Astrophysics Data System (ADS)

    Hagen, William E.; Holtzman, Julian C.

    The Army Terrain Integrated Interference Prediction System (ATIIPS), a CAD terrain based simulation tool for determining the degradation effects on a network on nonspread spectrum radios caused by a network of spread spectrum radios is presented. A brief overview of the program is given, with typical graphics displays shown. Typical results for both a link simulation of interference and for a network simulation, using a slow hopped FM/FSK spread spectrum interfering radio network on a narrow band FM/FSK fixed frequency digital radio are presented.

  5. Wide angle and narrow-band asymmetric absorption in visible and near-infrared regime through lossy Bragg stacks

    PubMed Central

    Shu, Shiwei; Zhan, Yawen; Lee, Chris; Lu, Jian; Li, Yang Yang

    2016-01-01

    Absorber is an important component in various optical devices. Here we report a novel type of asymmetric absorber in the visible and near-infrared spectrum which is based on lossy Bragg stacks. The lossy Bragg stacks can achieve near-perfect absorption at one side and high reflection at the other within the narrow bands (several nm) of resonance wavelengths, whereas display almost identical absorption/reflection responses for the rest of the spectrum. Meanwhile, this interesting wavelength-selective asymmetric absorption behavior persists for wide angles, does not depend on polarization, and can be ascribed to the lossy characteristics of the Bragg stacks. Moreover, interesting Fano resonance with easily tailorable peak profiles can be realized using the lossy Bragg stacks. PMID:27251768

  6. The method for scanning reshaping the spectrum of chirped laser pulse based on the quadratic electro-optic effects

    NASA Astrophysics Data System (ADS)

    Ye, Rong; Yin, Ming; Wu, Xianyun; Tan, Hang

    2017-10-01

    T A new method for scanning reshaping the spectrum of chirped laser pulse based on quadratic electro-optic effects is proposed. The scanning reshaping scheme with a two-beam interference system is designed and the spectrum reshaping properties are analyzed theoretically. For the Gaussian chirped laser pulse with central wavelength λ0=800nm, nearly flat-topped spectral profiles with wider bandwidth is obtained with the proposed scanning reshaping method, which is beneficial to compensate for the gain narrowing effect in CPA and OPCPA. Further numerical simulations show that the reshaped spectrum is sensitive to the time-delay and deviation of the voltage applied to the crystal. In order to avoid narrowing or distorting the reshaped spectrum pointing to target, it is necessary to reduce the unfavorable deviations. With the rapid and wide applications of ultra-short laser pulse supported by some latter research results including photo-associative formation of ultra-cold molecules from ultra-cold atoms[1-3], laser-induced communications[4], capsule implosions on the National Ignition Facility(NIF)[5-6], the control of the temporal and spectral profiles of laser pulse is very important and urgently need to be addressed. Generally, the control of the pulse profiles depends on practical applications, ranging from femtosecond and picosecond to nanosecond. For instance, the basic shaping setup is a Fourier transform system for ultra-short laser pulse. The most important element is a spatially patterned mask which modulates the phase or amplitude, or sometimes the polarization after the pulse is decomposed into its constituent spectral components by usually a grating and a lens[7]. One of the generation techniques of ultra-short laser pulse is the chirped pulse amplifications(CPA), which brings a new era of development for high energy and high peak intensity ultra-short laser pulse, proposed by D. Strcik and G. Mourou from the chirping radar technology in microwave region

  7. Oviposition Substrate of the Mountain Fly Drosophila nigrosparsa (Diptera: Drosophilidae)

    PubMed Central

    Tratter, Magdalena; Bächli, Gerhard; Kirchmair, Martin; Kaufmann, Rüdiger; Arthofer, Wolfgang; Schlick-Steiner, Birgit C.; Steiner, Florian M.

    2016-01-01

    The survival of insect larvae often depends on the mother’s choice of oviposition substrate, and thus, this choice is an essential part of an insect species’ ecology. Especially species with narrow substrate preferences may suffer from changes in substrate availability triggered by, for example, climate change. Recent climate warming is affecting species directly (e.g., physiology) but also indirectly (e.g., biological interactions) leading to mismatching phenologies and distributions. However, the preferred oviposition substrate is still unknown for many drosophilid species, especially for those at higher elevations. In this study, we investigated the oviposition-substrate preference of the montane-alpine fly Drosophila nigrosparsa in rearing and multiple-choice experiments using natural substrates in the laboratory. Insect emergence from field-collected substrates was tested. More than 650 insects were reared from natural substrates, among them 152 drosophilids but no individual of D. nigrosparsa. In the multiple-choice experiments, D. nigrosparsa preferred ovipositing on mushrooms (> 93% of eggs); additionally, a few eggs were laid on berries but none on other substrates such as cow faeces, rotten plant material, and soil. The flies laid 24 times more eggs per day when mushrooms were included in the substrates than when they were excluded. We infer that D. nigrosparsa is a mushroom breeder with some variation in oviposition choice. The flies favoured some mushrooms over others, but they were not specialised on a single fungal taxon. Although it is unclear if and how climate change will affect D. nigrosparsa, our results indicate that this species will not be threatened by oviposition-substrate limitations in the near future because of the broad altitudinal distribution of the mushrooms considered here, even if the flies will have to shift upwards to withstand increasing temperatures. PMID:27788257

  8. Spectrum bandwidth narrowing of Thomson scattering X-rays with energy chirped electron beams from laser wakefield acceleration

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Xu, Tong; Chen, Min, E-mail: minchen@sjtu.edu.cn; Li, Fei-Yu

    2014-01-06

    We study incoherent Thomson scattering between an ultrashort laser pulse and an electron beam accelerated from a laser wakefield. The energy chirp effects of the accelerated electron beam on the final radiation spectrum bandwidth are investigated. It is found that the scattered X-ray radiation has the minimum spectrum width and highest intensity as electrons are accelerated up to around the dephasing point. Furthermore, it is proposed that the electron acceleration process inside the wakefield can be studied by use of 90° Thomson scattering. The dephasing position and beam energy chirp can be deduced from the intensity and bandwidth of themore » scattered radiation.« less

  9. Photo-Detection on Narrow-Bandgap High-Mobility 2D Semiconductors

    NASA Astrophysics Data System (ADS)

    Charnas, Adam; Qiu, Gang; Deng, Yexin; Wang, Yixiu; Du, Yuchen; Yang, Lingming; Wu, Wenzhuo; Ye, Peide

    Photo-detection and energy harvesting device concepts have been demonstrated widely in 2D materials such as graphene, TMDs, and black phosphorus. In this work, we demonstrate anisotropic photo-detection achieved using devices fabricated from hydrothermally grown narrow-bandgap high-mobility 2D semiconductor. Back-gated FETs were fabricated by transferring the 2D flakes onto a Si/SiO2 substrate and depositing various metal contacts across the flakes to optimize the access resistance for optoelectronic devices. Photo-responsivity was measured and mapped by slightly biasing the devices and shining a laser spot at different locations of the device to observe and map the resulting photo-generated current. Optimization of the Schottky barrier height for both n and p at the metal-2D interfaces using asymmetric contact engineering was performed to improve device performance.

  10. A design of calibration single star simulator with adjustable magnitude and optical spectrum output system

    NASA Astrophysics Data System (ADS)

    Hu, Guansheng; Zhang, Tao; Zhang, Xuan; Shi, Gentai; Bai, Haojie

    2018-03-01

    In order to achieve multi-color temperature and multi-magnitude output, magnitude and temperature can real-time adjust, a new type of calibration single star simulator was designed with adjustable magnitude and optical spectrum output in this article. xenon lamp and halogen tungsten lamp were used as light source. The control of spectrum band and temperature of star was realized with different multi-beam narrow band spectrum with light of varying intensity. When light source with different spectral characteristics and color temperature go into the magnitude regulator, the light energy attenuation were under control by adjusting the light luminosity. This method can completely satisfy the requirements of calibration single star simulator with adjustable magnitude and optical spectrum output in order to achieve the adjustable purpose of magnitude and spectrum.

  11. Spectrum of 100-kyr glacial cycle: Orbital inclination, not eccentricity

    PubMed Central

    Muller, Richard A.; MacDonald, Gordon J.

    1997-01-01

    Spectral analysis of climate data shows a strong narrow peak with period ≈100 kyr, attributed by the Milankovitch theory to changes in the eccentricity of the earth’s orbit. The narrowness of the peak does suggest an astronomical origin; however the shape of the peak is incompatible with both linear and nonlinear models that attribute the cycle to eccentricity or (equivalently) to the envelope of the precession. In contrast, the orbital inclination parameter gives a good match to both the spectrum and bispectrum of the climate data. Extraterrestrial accretion from meteoroids or interplanetary dust is proposed as a mechanism that could link inclination to climate, and experimental tests are described that could prove or disprove this hypothesis. PMID:11607741

  12. The Development of the Neural Substrates of Cognitive Control in Adolescents with Autism Spectrum Disorders

    PubMed Central

    Solomon, Marjorie; Yoon, Jong; Ragland, J. Daniel; Niendam, Tara; Lesh, Tyler A.; Fairbrother, Wonja; Carter, Cameron S.

    2013-01-01

    Background Autism spectrum disorders (ASD) involve impairments in cognitive control. In typical development (TYP), neural systems underlying cognitive control undergo substantial maturation during adolescence. Development is delayed in adolescents with ASD. Little is known about the neural substrates of this delay. Method We used event-related functional magnetic resonance imaging (fMRI) and a cognitive control task involving overcoming a prepotent response tendency to examine the development of cognitive control in young (ages 12–15; n = 13 with ASD and n = 13 with TYP) and older (ages 16–18; n= 14 with ASD and n = 14 with TYP) adolescents with whole-brain voxel-wise univariate and task-related functional connectivity analyses. Results Older ASD and TYP showed reduced activation in sensory and premotor areas relative to younger ones. The older ASD group showed reduced left parietal activation relative to TYP. Functional connectivity analyses showed a significant age by group interaction with the older ASD group exhibiting increased functional connectivity strength between the ventrolateral prefrontal cortex (VLPFC) and the anterior cingulate cortex (ACC), bilaterally. This functional connectivity strength was related to task performance in ASD, whereas that between DLPFC and parietal cortex (BA 9 and BA 40) was related to task performance in TYP. Conclusions Adolescents with ASD rely more on “reactive” cognitive control, involving last minute conflict detection and control implementation by the ACC and VLPFC, versus “proactive” cognitive control requiring processing by DLPFC and parietal cortex. Findings await replication in larger longitudinal studies that examine their functional consequences and amenability to intervention. PMID:24209777

  13. Optically trapped atomic resonant devices for narrow linewidth spectral imaging

    NASA Astrophysics Data System (ADS)

    Qian, Lipeng

    This thesis focuses on the development of atomic resonant devices for spectroscopic applications. The primary emphasis is on the imaging properties of optically thick atomic resonant fluorescent filters and their applications. In addition, this thesis presents a new concept for producing very narrow linewidth light as from an atomic vapor lamp pumped by a nanosecond pulse system. This research was motivated by application for missile warning system, and presents an innovative approach to a wide angle, ultra narrow linewidth imaging filter using a potassium vapor cell. The approach is to image onto and collect the fluorescent photons emitted from the surface of an optically thick potassium vapor cell, generating a 2 GHz pass-band imaging filter. This linewidth is narrow enough to fall within a Fraunhefer dark zone in the solar spectrum, thus make the detection solar blind. Experiments are conducted to measure the absorption line shape of the potassium resonant filter, the quantum efficiency of the fluorescent behavior, and the resolution of the fluorescent image. Fluorescent images with different spatial frequency components are analyzed by using a discrete Fourier transform, and the imaging capability of the fluorescent filter is described by its Modulation Transfer Function. For the detection of radiation that is spectrally broader than the linewidth of the potassium imaging filter, the fluorescent image is seen to be blurred by diffuse fluorescence from the slightly off resonant photons. To correct this, an ultra-thin potassium imaging filter is developed and characterized. The imaging property of the ultra-thin potassium imaging cell is tested with a potassium seeded flame, yielding a resolution image of ˜ 20 lines per mm. The physics behind the atomic resonant fluorescent filter is radiation trapping. The diffusion process of the resonant photons trapped in the atomic vapor is theoretically described in this thesis. A Monte Carlo method is used to simulate the

  14. Spectrum Analyzers Incorporating Tunable WGM Resonators

    NASA Technical Reports Server (NTRS)

    Savchenkov, Anatoliy; Matsko, Andrey; Strekalov, Dmitry; Maleki, Lute

    2009-01-01

    A photonic instrument is proposed to boost the resolution for ultraviolet/ optical/infrared spectral analysis and spectral imaging allowing the detection of narrow (0.00007-to-0.07-picometer wavelength resolution range) optical spectral signatures of chemical elements in space and planetary atmospheres. The idea underlying the proposal is to exploit the advantageous spectral characteristics of whispering-gallery-mode (WGM) resonators to obtain spectral resolutions at least three orders of magnitude greater than those of optical spectrum analyzers now in use. Such high resolutions would enable measurement of spectral features that could not be resolved by prior instruments.

  15. Narrow-headed garter snake (Thamnophis rufipunctatus)

    USGS Publications Warehouse

    Nowak, Erika M.

    2006-01-01

    The narrow-headed garter snake is a harmless, nonvenomous snake that is distinguished by its elongated, triangular-shaped head and the red or dark spots on its olive to tan body. Today, the narrow-headed garter snake is a species of special concern in the United States because of its decline over much of its historic range. Arizona's Oak Creek has historically contained the largest population of narrow-headed garter snakes in the United States. The U.S. Geological Survey (USGS) and the Arizona Game and Fish Department jointly funded research by USGS scientists in Oak Creek to shed light on the factors causing declining population numbers. The research resulted in better understanding of the snake's habitat needs, winter and summer range, and dietary habits. Based on the research findings, the U.S. Forest Service has developed recommendations that visitors and local residents can adopt to help slow the decline of the narrow-headed garter snake in Oak Creek.

  16. Spectral evolution and extreme value analysis of non-linear numerical simulations of narrow band random surface gravity waves.

    NASA Astrophysics Data System (ADS)

    Socquet-Juglard, H.; Dysthe, K. B.; Trulsen, K.; Liu, J.; Krogstad, H. E.

    2003-04-01

    Numerical simulations of a narrow band gaussian spectrum of random surface gravity waves have been carried out in two and three spatial dimensions [7]. Different types of non-linear Schr&{uml;o}dinger equations, [1] and [4], have been used in these simulations. Simulations have now been carried with a JONSWAP spectrum associated with a spreading function of the type cosine-squared [5]. The evolution of the spectrum, skewness, kurtosis, ... will be presented. In addition, some results about stochastic properties of the surface will be shown. Based on the approach found in [2], [3] and [6], the results are presented in terms of deviations from linear Gaussian theory and the standard second order small slope perturbation theory. begin{thebibliography}{9} bibitem{kk96} Trulsen, K. &Dysthe, K. B. (1996). A modified nonlinear Schr&{uml;o}dinger equation for broader bandwidth gravity waves on deep water. Wave Motion, 24, pp. 281-289. bibitem{BK2000} Krogstad, H.E. and S.F. Barstow (2000). A uniform approach to extreme value analysis of ocean waves, Proc. ISOPE'2000, Seattle, USA, 3, pp. 103-108. bibitem{PRK} Prevosto, M., H. E. Krogstad and A. Robin (2000). Probability distributions for maximum wave and crest heights, Coast. Eng., 40, 329-360. bibitem{ketal} Trulsen, K., Kliakhandler, I., Dysthe, K. B. &Velarde, M. G. (2000) On weakly nonlinear modulation of waves on deep water, Phys. Fluids, 12, pp. L25-L28. bibitem{onorato} Onorato, M., Osborne, A.R. and Serio, M. (2002) Extreme wave events in directional, random oceanic sea states, Phys. Fluids, 14, pp. 2432-2437. bibitem{BK2002} Krogstad, H.E. and S.F. Barstow (2002). Analysis and Applications of Second Order Models for the Maximum Crest height, % Proc. 21nd Int. Conf. Offshore Mechanics and Arctic Engineering, Oslo. Paper no. OMAE2002-28479. bibitem{JFMP} Dysthe, K. B., Trulsen, K., Krogstad, H. E. and Socquet-Juglard, H. (2002, in press) Evolution of a narrow band spectrum of random surface gravity waves, J. Fluid

  17. Energy transport in weakly nonlinear wave systems with narrow frequency band excitation.

    PubMed

    Kartashova, Elena

    2012-10-01

    A novel discrete model (D model) is presented describing nonlinear wave interactions in systems with small and moderate nonlinearity under narrow frequency band excitation. It integrates in a single theoretical frame two mechanisms of energy transport between modes, namely, intermittency and energy cascade, and gives the conditions under which each regime will take place. Conditions for the formation of a cascade, cascade direction, conditions for cascade termination, etc., are given and depend strongly on the choice of excitation parameters. The energy spectra of a cascade may be computed, yielding discrete and continuous energy spectra. The model does not require statistical assumptions, as all effects are derived from the interaction of distinct modes. In the example given-surface water waves with dispersion function ω(2)=gk and small nonlinearity-the D model predicts asymmetrical growth of side-bands for Benjamin-Feir instability, while the transition from discrete to continuous energy spectrum, excitation parameters properly chosen, yields the saturated Phillips' power spectrum ~g(2)ω(-5). The D model can be applied to the experimental and theoretical study of numerous wave systems appearing in hydrodynamics, nonlinear optics, electrodynamics, plasma, convection theory, etc.

  18. Intermolecular interactions and substrate effects for an adamantane monolayer on a Au(111) surface

    NASA Astrophysics Data System (ADS)

    Sakai, Yuki; Nguyen, Giang D.; Capaz, Rodrigo B.; Coh, Sinisa; Pechenezhskiy, Ivan V.; Hong, Xiaoping; Wang, Feng; Crommie, Michael F.; Saito, Susumu; Louie, Steven G.; Cohen, Marvin L.

    2013-12-01

    We study theoretically and experimentally the infrared (IR) spectrum of an adamantane monolayer on a Au(111) surface. Using a STM-based IR spectroscopy technique (IRSTM) we are able to measure both the nanoscale structure of an adamantane monolayer on Au(111) as well as its infrared spectrum, while DFT-based ab initio calculations allow us to interpret the microscopic vibrational dynamics revealed by our measurements. We find that the IR spectrum of an adamantane monolayer on Au(111) is substantially modified with respect to the gas-phase IR spectrum. The first modification is caused by the adamantane-adamantane interaction due to monolayer packing, and it reduces the IR intensity of the 2912 cm-1 peak (gas phase) by a factor of 3.5. The second modification originates from the adamantane-gold interaction, and it increases the IR intensity of the 2938 cm-1 peak (gas phase) by a factor of 2.6 and reduces its frequency by 276 cm-1. We expect that the techniques described here can be used for an independent estimate of substrate effects and intermolecular interactions in other diamondoid molecules and for other metallic substrates.

  19. Advanced fabrication of single-crystalline silver nanopillar on SiO{sub 2} substrate

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mori, Tomohiro, E-mail: tomohiro-mori@wakayama-kg.jp, E-mail: kenzo@eng.kagawa-u.ac.jp; Industrial Technology Center of Wakayama Prefecture, Ogura 60, Wakayama 649-6261; Tanaka, Yasuhiro

    2016-01-25

    Nanoscale crystallographic textures have received very little attention in research on surface plasmons using metallic nanostructures. A single-crystalline metallic nanostructure with a controlled crystallographic texture is expected to reduce optical losses. We elucidated the grain growth mechanism in silver thin films deposited on a highly transparent SiO{sub 2} substrate by electron backscatter diffraction methods with nanoscale resolution. At higher substrate temperatures, the grain growth was facilitated but the preferred orientation was not achieved. Moreover, we fabricated a single-crystalline silver nanopillar in a (111)-oriented large growing grain, which was controlled by varying the substrate temperature during film deposition by focused ion-beammore » milling. Furthermore, the light intensity of the scattering spectrum was measured for a single-crystalline silver nanopillar (undersurface diameter: 200 nm) for which surface plasmon resonance was observed. The single-crystalline silver nanopillar exhibits a stronger and sharper spectrum than the polycrystalline silver nanopillar. These results can be applied to the direct fabrication of a single-crystalline silver nanopillar using only physical processing.« less

  20. Reduced tract integrity of the model for social communication is a neural substrate of social communication deficits in autism spectrum disorder.

    PubMed

    Lo, Yu-Chun; Chen, Yu-Jen; Hsu, Yung-Chin; Tseng, Wen-Yih Isaac; Gau, Susan Shur-Fen

    2017-05-01

    Autism spectrum disorder (ASD) is a neurodevelopmental disorder with social communication deficits as one of the core symptoms. Recently, a five-level model for the social communication has been proposed in which white matter tracts corresponding to each level of the model are identified. Given that the model for social communication subserves social language functions, we hypothesized that the tract integrity of the model for social communication may be reduced in ASD, and the reduction may be related to social communication deficits. Sixty-two right-handed boys with ASD and 55 typically developing (TD) boys received clinical evaluations, intelligence tests, the Social Communication Questionnaire (SCQ), and MRI scans. Generalized fractional anisotropy (GFA) was measured by diffusion spectrum imaging to indicate the microstructural integrity of the tracts for each level of the social communication model. Group difference in the tract integrity and its relationship with the SCQ subscales of social communication and social interaction were investigated. We found that the GFA values of the superior longitudinal fasciculus III (SLF III, level 1) and the frontal aslant tracts (FAT, level 2) were decreased in ASD compared to TD. Moreover, the GFA values of the SLF III and the FAT were associated with the social interaction subscale in ASD. The tract integrity of the model for social communication is reduced in ASD, and the reduction is associated with impaired social interaction. Our results support that reduced tract integrity of the model for social communication might be a neural substrate of social communication deficits in ASD. © 2016 Association for Child and Adolescent Mental Health.

  1. Narrow chaotic compound autoionizing states in atomic spectra

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Flambaum, V.V.; Gribakina, A.A.; Gribakin, G.F.

    1996-09-01

    Simultaneous excitation of several valence electrons in atoms gives rise to a dense spectrum of compound autoionizing states (AIS). These states are almost chaotic superpositions of large numbers of many-electron basis states built of single-electron orbitals. The mean level spacing {ital D} between such states is very small (e.g., {ital D}{lt}0.01 eV for the numerical example of {ital J}{sup {pi}}=4{sup {minus}} states of Ce just above the ionization threshold). The autoionization widths of these states estimated by perturbations, {gamma}=2{pi}{vert_bar}{ital W}{vert_bar}{sup 2}, where {ital W} is the Coulomb matrix element coupling the AIS to the continuum, are also small, but comparablemore » with {ital D} in magnitude: {gamma}{approximately}{ital D}. Hence the nonperturbative interaction of AIS with each other via the continuum is very essential. It suppresses greatly the widths of the autoionizing resonances ({Gamma}{approx_equal}{ital D}{sup 2}/3{gamma}{lt}{ital D}), and leads to the emergence of a {open_quote}{open_quote}collective{close_quote}{close_quote} doorway state which accumulates a large share of the total width. This state is in essence a modified single-particle continuum decoupled from the resonances due to its large width. Narrow compound AIS should be a common feature of atomic spectra at energies sufficient for excitation of several electrons above the ground-state configuration. The narrow resonances can be observed as peaks in the photoabsorption, or, in electron-ion scattering, as Fano-type profiles on the background provided by the wide doorway-state resonance. It is also shown that the statistics of electromagnetic and autoionization amplitudes involving compound states are close to Gaussian. {copyright} {ital 1996 The American Physical Society.}« less

  2. Between Scylla and Charybdis: Hydrophobic Graphene-Guided Water Diffusion on Hydrophilic Substrates

    PubMed Central

    Kim, Jin-Soo; Choi, Jin Sik; Lee, Mi Jung; Park, Bae Ho; Bukhvalov, Danil; Son, Young-Woo; Yoon, Duhee; Cheong, Hyeonsik; Yun, Jun-Nyeong; Jung, Yousung; Park, Jeong Young; Salmeron, Miquel

    2013-01-01

    The structure of water confined in nanometer-sized cavities is important because, at this scale, a large fraction of hydrogen bonds can be perturbed by interaction with the confining walls. Unusual fluidity properties can thus be expected in the narrow pores, leading to new phenomena like the enhanced fluidity reported in carbon nanotubes. Crystalline mica and amorphous silicon dioxide are hydrophilic substrates that strongly adsorb water. Graphene, on the other hand, interacts weakly with water. This presents the question as to what determines the structure and diffusivity of water when intercalated between hydrophilic substrates and hydrophobic graphene. Using atomic force microscopy, we have found that while the hydrophilic substrates determine the structure of water near its surface, graphene guides its diffusion, favouring growth of intercalated water domains along the C-C bond zigzag direction. Molecular dynamics and density functional calculations are provided to help understand the highly anisotropic water stripe patterns observed. PMID:23896759

  3. Narrow Networks on the Individual Marketplace in 2017.

    PubMed

    Polski, Daniel; Weiner, Janet; Zhang, Yuehan

    2017-09-01

    This Issue Brief describes the breadth of physician networks on the ACA marketplaces in 2017. We find that the overall rate of narrow networks is 21%, which is a decline since 2014 (31%) and 2016 (25%). Narrow networks are concentrated in plans sold on state-based marketplaces, at 42%, compared to 10% of plans on federally-facilitated marketplaces. Issuers that have traditionally offered Medicaid coverage have the highest prevalence of narrow network plans at 36%, with regional/local plans and provider-based plans close behind at 27% and 30%. We also find large differences in narrow networks by state and by plan type.

  4. Autocorrelation Analysis Combined with a Wavelet Transform Method to Detect and Remove Cosmic Rays in a Single Raman Spectrum.

    PubMed

    Maury, Augusto; Revilla, Reynier I

    2015-08-01

    Cosmic rays (CRs) occasionally affect charge-coupled device (CCD) detectors, introducing large spikes with very narrow bandwidth in the spectrum. These CR features can distort the chemical information expressed by the spectra. Consequently, we propose here an algorithm to identify and remove significant spikes in a single Raman spectrum. An autocorrelation analysis is first carried out to accentuate the CRs feature as outliers. Subsequently, with an adequate selection of the threshold, a discrete wavelet transform filter is used to identify CR spikes. Identified data points are then replaced by interpolated values using the weighted-average interpolation technique. This approach only modifies the data in a close vicinity of the CRs. Additionally, robust wavelet transform parameters are proposed (a desirable property for automation) after optimizing them with the application of the method in a great number of spectra. However, this algorithm, as well as all the single-spectrum analysis procedures, is limited to the cases in which CRs have much narrower bandwidth than the Raman bands. This might not be the case when low-resolution Raman instruments are used.

  5. Fermi/Large Area Telescope Discovery of Gamma-Ray Emission from a Relativistic Jet in the Narrow-Line Quasar PMN J0948+0022

    DOE PAGES

    Abdo, A. A.; Ackermann, M.; Ajello, M.; ...

    2009-06-17

    In this paper, we report the discovery by the Large Area Telescope (LAT) onboard the Fermi Gamma-Ray Space Telescope of high-energy γ-ray emission from the peculiar quasar PMN J0948+0022 (z = 0.5846). The optical spectrum of this object exhibits rather narrow Hβ (FWHM(Hβ) ~1500 km s –1), weak forbidden lines, and is therefore classified as a narrow-line type I quasar. This class of objects is thought to have relatively small black hole mass and to accrete at a high Eddington ratio. The radio loudness and variability of the compact radio core indicate the presence of a relativistic jet. Quasi-simultaneous radio/optical/X-raymore » and γ-ray observations are presented. Both radio and γ-ray emissions (observed over five months) are strongly variable. The simultaneous optical and X-ray data from Swift show a blue continuum attributed to the accretion disk and a hard X-ray spectrum attributed to the jet. The resulting broadband spectral energy distribution (SED) and, in particular, the γ-ray spectrum measured by Fermi are similar to those of more powerful Flat-Spectrum Radio Quasars (FSRQs). A comparison of the radio and γ-ray characteristics of PMN J0948+0022 with the other blazars detected by LAT shows that this source has a relatively low radio and γ-ray power with respect to other FSRQs. The physical parameters obtained from modeling the SED also fall at the low power end of the FSRQ parameter region discussed in Celotti & Ghisellini. Finally, we suggest that the similarity of the SED of PMN J0948+0022 to that of more massive and more powerful quasars can be understood in a scenario in which the SED properties depend on the Eddington ratio rather than on the absolute power.« less

  6. Coherent optical effect on time-resolved vibrational SFG spectrum of adsorbates

    NASA Astrophysics Data System (ADS)

    Ueba, H.; Sawabu, T.; Mii, T.

    2002-04-01

    We present a theory to study the influence of the coherent mixing between pump-infrared and probe-visible pulse on a time-resolved sum-frequency generation (TR-SFG) spectrum for vibrations at surfaces. The general formula of the time-dependent and its Fourier transform of the SFG polarization and its Fourier transform allows us to calculate the time-resolved vibrational SFG spectrum and the transient characteristics of the SFG intensity as a function of the delay time td between the pump-infrared and probe-visible pulse. It is found the coherent optical effect manifests itself in the broadening and narrowing of the SFG spectrum with the intrinsic width of T2 at negative and positive td, respectively, being in qualitative agreement with recent experimental results. The influence of the coherent mixing on the transient behavior of the SFG intensity is also discussed in conjunction to the T2 determination.

  7. An Ultraviolet Spectrum of the Tidal Disruption Flare ASASSN-14li

    NASA Astrophysics Data System (ADS)

    Cenko, S. Bradley; Cucchiara, Antonino; Roth, Nathaniel; Veilleux, Sylvain; Prochaska, J. Xavier; Yan, Lin; Guillochon, James; Maksym, W. Peter; Arcavi, Iair; Butler, Nathaniel R.; Filippenko, Alexei V.; Fruchter, Andrew S.; Gezari, Suvi; Kasen, Daniel; Levan, Andrew J.; Miller, Jon M.; Pasham, Dheeraj R.; Ramirez-Ruiz, Enrico; Strubbe, Linda E.; Tanvir, Nial R.; Tombesi, Francesco

    2016-02-01

    We present a Hubble Space Telescope Space Telescope Imaging Spectrograph spectrum of ASASSN-14li, the first rest-frame ultraviolet (UV) spectrum of a tidal disruption flare (TDF). The underlying continuum is well fit by a blackbody with {T}{UV}=3.5× {10}4 K, an order of magnitude smaller than the temperature inferred from X-ray spectra (and significantly more precise than previous efforts based on optical and near-UV photometry). Superimposed on this blue continuum, we detect three classes of features: narrow absorption from the Milky Way (probably a high-velocity cloud), and narrow absorption and broad (˜2000-8000 km s-1) emission lines at or near the systemic host velocity. The absorption lines are blueshifted with respect to the emission lines by Δv = -(250-400) km s-1. Due both to this velocity offset and the lack of common low-ionization features (Mg II, Fe II), we argue these arise from the same absorbing material responsible for the low-velocity outflow discovered at X-ray wavelengths. The broad nuclear emission lines display a remarkable abundance pattern: N III], N IV], and He II are quite prominent, while the common quasar emission lines of C III] and Mg II are weak or entirely absent. Detailed modeling of this spectrum will help elucidate fundamental questions regarding the nature of the emission processes at work in TDFs, while future UV spectroscopy of ASASSN-14li would help to confirm (or refute) the previously proposed connection between TDFs and “N-rich” quasars.

  8. An Ultraviolet Spectrum of the Tidal Disruption Flare ASASSN-14li

    NASA Technical Reports Server (NTRS)

    Cenko, S. Bradley; Cucchiara, Antonio; Roth, Nathaniel; Veilleux, Sylvain; Prochaska, J. Xavier; Yan, Lin; Guillochon, James; Maksym, W. Peter; Arcavi, Iair; Butler, Nathaniel R.

    2016-01-01

    We present a Hubble Space Telescope Space Telescope Imaging Spectrograph spectrum of ASASSN-14li, the first rest-frame ultraviolet (UV) spectrum of a tidal disruption flare (TDF). The underlying continuum is well fit by a blackbody with T(sub UV) = 3.5 x 10(exp. 4) K, an order of magnitude smaller than the temperature inferred from X-ray spectra (and significantly more precise than previous efforts based on optical and near-UV photometry).Superimposed on this blue continuum, we detect three classes of features: narrow absorption from the Milky Way (probably a high-velocity cloud), and narrow absorption and broad {approx. 2000-8000 km s(exp. -1)} emission lines at or near the systemic host velocity. The absorption lines are blueshifted with respect to the emission lines by Delta(sub v) = -(250-400) km s(exp. -1). Due both to this velocity offset and the lack of common low-ionization features (Mg II, Fe II), we argue these arise from the same absorbing material responsible for the low-velocity outflow discovered at X-ray wavelengths. The broad nuclear emission lines display a remarkable abundance pattern: N III], N IV], and He II are quite prominent, while the common quasar emission lines of C III] and Mg II are weak or entirely absent. Detailed modeling of this spectrum will help elucidate fundamental questions regarding the nature of the emission processes at work in TDFs, while future UV spectroscopy of ASASSN-14li would help to confirm (or refute) the previously proposed connection between TDFs and N-rich quasars.

  9. [EMD Time-Frequency Analysis of Raman Spectrum and NIR].

    PubMed

    Zhao, Xiao-yu; Fang, Yi-ming; Tan, Feng; Tong, Liang; Zhai, Zhe

    2016-02-01

    This paper analyzes the Raman spectrum and Near Infrared Spectrum (NIR) with time-frequency method. The empirical mode decomposition spectrum becomes intrinsic mode functions, which the proportion calculation reveals the Raman spectral energy is uniform distributed in each component, while the NIR's low order intrinsic mode functions only undertakes fewer primary spectroscopic effective information. Both the real spectrum and numerical experiments show that the empirical mode decomposition (EMD) regard Raman spectrum as the amplitude-modulated signal, which possessed with high frequency adsorption property; and EMD regards NIR as the frequency-modulated signal, which could be preferably realized high frequency narrow-band demodulation during first-order intrinsic mode functions. The first-order intrinsic mode functions Hilbert transform reveals that during the period of empirical mode decomposes Raman spectrum, modal aliasing happened. Through further analysis of corn leaf's NIR in time-frequency domain, after EMD, the first and second orders components of low energy are cut off, and reconstruct spectral signal by using the remaining intrinsic mode functions, the root-mean-square error is 1.001 1, and the correlation coefficient is 0.981 3, both of these two indexes indicated higher accuracy in re-construction; the decomposition trend term indicates the absorbency is ascending along with the decreasing to wave length in the near-infrared light wave band; and the Hilbert transform of characteristic modal component displays, 657 cm⁻¹ is the specific frequency by the corn leaf stress spectrum, which could be regarded as characteristic frequency for identification.

  10. Monitoring substrate enables real-time regulation of a protein localization pathway.

    PubMed

    Ito, Koreaki; Mori, Hiroyuki; Chiba, Shinobu

    2018-06-01

    Protein localization machinery supports cell survival and physiology, suggesting the potential importance of its expression regulation. Here, we summarize a remarkable scheme of regulation, which allows real-time feedback regulation of the machinery expression. A class of regulatory nascent polypeptides, called monitoring substrates, undergoes force-sensitive translation arrest. The resulting ribosome stalling on the mRNA then affects mRNA folding to expose the ribosome-binding site of the downstream target gene and upregulate its translation. The target gene encodes a component of the localization machinery, whose physical action against the monitoring substrate leads to arrest cancellation. Thus, this scheme of feedback loop allows the cell to adjust the amount of the machinery to correlate inversely with the effectiveness of the process at a given moment. The system appears to have emerged late in evolution, in which a narrow range of organisms selected a distinct monitoring substrate-machinery combination. Currently, regulatory systems of SecM-SecA, VemP-SecDF2 and MifM-YidC2 are known to occur in different bacterial species.

  11. On the levels of enzymatic substrate specificity: Implications for the early evolution of metabolic pathways

    NASA Technical Reports Server (NTRS)

    Lazcano, A.; Diaz-Villagomez, E.; Mills, T.; Oro, J.

    1995-01-01

    The most frequently invoked explanation for the origin of metabolic pathways is the retrograde evolution hypothesis. In contrast, according to the so-called 'patchwork' theory, metabolism evolved by the recruitment of relatively inefficient small enzymes of broad specificity that could react with a wide range of chemically related substrates. In this paper it is argued that both sequence comparisons and experimental results on enzyme substrate specificity support the patchwork assembly theory. The available evidence supports previous suggestions that gene duplication events followed by a gradual neoDarwinian accumulation of mutations and other minute genetic changes lead to the narrowing and modification of enzyme function in at least some primordial metabolic pathways.

  12. Clinical studies of the High-Intensity Narrow-Spectrum light Environmental Decontamination System (HINS-light EDS), for continuous disinfection in the burn unit inpatient and outpatient settings.

    PubMed

    Bache, Sarah E; Maclean, Michelle; MacGregor, Scott J; Anderson, John G; Gettinby, George; Coia, John E; Taggart, Ian

    2012-02-01

    Infections are the leading cause of morbidity and mortality in burn patients and prevention of contamination from exogenous sources including the hospital environment is becoming increasingly emphasised. The High-Intensity Narrow-Spectrum light Environmental Decontamination System (HINS-light EDS) is bactericidal yet safe for humans, allowing continuous disinfection of the environment surrounding burn patients. Environmental samples were collected from inpatient isolation rooms and the outpatient clinic in the burn unit, and comparisons were then made between the bacterial contamination levels observed with and without use of the HINS-light EDS. Over 1000 samples were taken. Inpatient studies, with sampling carried out at 0800 h, demonstrated a significant reduction in the average number of bacterial colonies following HINS-light EDS use of between 27% and 75%, (p<0.05). There was more variation when samples were taken at times of increased activity in the room. Outpatient studies during clinics demonstrated a 61% efficacy in the reduction of bacterial contamination on surfaces throughout the room during the course of a clinic (p=0.02). The results demonstrate that use of the HINS-light EDS allows efficacious bacterial reductions over and above that achieved by standard cleaning and infection control measures in both inpatient and outpatient settings in the burn unit. Copyright © 2011 Elsevier Ltd and ISBI. All rights reserved.

  13. Nonlinear optical response in narrow graphene nanoribbons

    NASA Astrophysics Data System (ADS)

    Karimi, Farhad; Knezevic, Irena

    We present an iterative method to calculate the nonlinear optical response of armchair graphene nanoribbons (aGNRs) and zigzag graphene nanoribbons (zGNRs) while including the effects of dissipation. In contrast to methods that calculate the nonlinear response in the ballistic (dissipation-free) regime, here we obtain the nonlinear response of an electronic system to an external electromagnetic field while interacting with a dissipative environment (to second order). We use a self-consistent-field approach within a Markovian master-equation formalism (SCF-MMEF) coupled with full-wave electromagnetic equations, and we solve the master equation iteratively to obtain the higher-order response functions. We employ the SCF-MMEF to calculate the nonlinear conductance and susceptibility, as well as to calculate the dependence of the plasmon dispersion and plasmon propagation length on the intensity of the electromagnetic field in GNRs. The electron scattering mechanisms included in this work are scattering with intrinsic phonons, ionized impurities, surface optical phonons, and line-edge roughness. Unlike in wide GNRs, where ionized-impurity scattering dominates dissipation, in ultra-narrow nanoribbons on polar substrates optical-phonon scattering and ionized-impurity scattering are equally prominent. Support by the U.S. Department of Energy, Office of Basic Energy Sciences, Division of Materials Sciences and Engineering under Award DE-SC0008712.

  14. Ring resonator based narrow-linewidth semiconductor lasers

    NASA Technical Reports Server (NTRS)

    Ksendzov, Alexander (Inventor)

    2005-01-01

    The present invention is a method and apparatus for using ring resonators to produce narrow linewidth hybrid semiconductor lasers. According to one embodiment of the present invention, the narrow linewidths are produced by combining the semiconductor gain chip with a narrow pass band external feedback element. The semi conductor laser is produced using a ring resonator which, combined with a Bragg grating, acts as the external feedback element. According to another embodiment of the present invention, the proposed integrated optics ring resonator is based on plasma enhanced chemical vapor deposition (PECVD) SiO.sub.2 /SiON/SiO.sub.2 waveguide technology.

  15. Bacteriocins and bacteriophage; a narrow-minded approach to food and gut microbiology.

    PubMed

    Mills, Susan; Ross, R Paul; Hill, Colin

    2017-08-01

    Bacteriocins and bacteriophage (phage) are biological tools which exhibit targeted microbial killing, a phenomenon which until recently was seen as a major drawback for their use as antimicrobial agents. However, in an age when the deleterious consequences of broad-spectrum antibiotics on human health have become apparent, there is an urgent need to develop narrow-spectrum substitutes. Indeed, disruption of the microbial communities which exist on and in our bodies can generate immediate and long-term negative effects and this is particularly borne out in the gut microbiota community whose disruption has been linked to a number of disorders reaching as far as the brain. Moreover, the antibiotic resistance crisis has resulted in our inability to treat many bacterial infections and has triggered the search for damage-limiting alternatives. As bacteriocins and phage are natural entities they are relatively easy to isolate and characterise and are also ideal candidates for improving food safety and quality, forfeiting the need for largely unpopular chemical preservatives. This review highlights the efficacy of both antimicrobial agents in terms of gut health and food safety and explores the body of scientific evidence supporting their effectiveness in both environments. © FEMS 2017. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  16. A practical method to fabricate gold substrates for surface-enhanced Raman spectroscopy.

    PubMed

    Tantra, Ratna; Brown, Richard J C; Milton, Martin J T; Gohil, Dipak

    2008-09-01

    We describe a practical method of fabricating surface-enhanced Raman spectroscopy (SERS) substrates based on dip-coating poly-L-lysine derivatized microscope slides in a gold colloidal suspension. The use of only commercially available starting materials in this preparation is particularly advantageous, aimed at both reducing time and the inconsistency associated with surface modification of substrates. The success of colloid deposition has been demonstrated by scanning electron microscopy (SEM) and the corresponding SERS response (giving performance comparable to the corresponding traditional colloidal SERS substrates). Reproducibility was evaluated by conducting replicate measurements across six different locations on the substrate and assessing the extent of the variability (standard deviation values of spectral parameters: peak width and height), in response to either Rhodamine 6G or Isoniazid. Of particular interest is the observation of how some peaks in a given spectrum are more susceptible to data variability than others. For example, in a Rhodamine 6G SERS spectrum, spectral parameters of the peak at 775 cm(-1) were shown to have a relative standard deviation (RSD) % of <10%, while the peak at 1573 cm(-1) has a RSD of >or=10%. This observation is best explained by taking into account spectral variations that arise from the effect of a chemisorption process and the local nature of chemical enhancement mechanisms, which affects the enhancement of some spectral peaks but not others (analogous to resonant Raman phenomenon).

  17. Ocular Biometrics of Myopic Eyes With Narrow Angles.

    PubMed

    Chong, Gabriel T; Wen, Joanne C; Su, Daniel Hsien-Wen; Stinnett, Sandra; Asrani, Sanjay

    2016-02-01

    The purpose of this study was to compare the ocular biometrics between myopic patients with and without narrow angles. Patients with a stable myopic refraction (myopia worse than -1.00 D spherical equivalent) were prospectively recruited. Angle status was assessed using gonioscopy and biometric measurements were performed using an anterior segment optical coherence tomography and an IOLMaster. A total of 29 patients (58 eyes) were enrolled with 13 patients (26 eyes) classified as having narrow angles and 16 patients (32 eyes) classified as having open angles. Baseline demographics of age, sex, and ethnicity did not differ significantly between the 2 groups. The patients with narrow angles were on average older than those with open angles but the difference did not reach statistical significance (P=0.12). The central anterior chamber depth was significantly less in the eyes with narrow angles (P=0.05). However, the average lens thickness, although greater in the eyes with narrow angles, did not reach statistical significance (P=0.10). Refractive error, axial lengths, and iris thicknesses did not differ significantly between the 2 groups (P=0.32, 0.47, 0.15). Narrow angles can occur in myopic eyes. Routine gonioscopy is therefore recommended for all patients regardless of refractive error.

  18. Intramyocardial arterial narrowing in dogs with subaortic stenosis.

    PubMed

    Falk, T; Jönsson, L; Pedersen, H D

    2004-09-01

    Earlier studies have described intramyocardial arterial narrowing based on hyperplasia and hypertrophy of the vessel wall in dogs with subaortic stenosis (SAS). In theory, such changes might increase the risk of sudden death, as they seem to do in heart disease in other species. This retrospective pathological study describes and quantifies intramyocardial arterial narrowing in 44 dogs with naturally occurring SAS and in eight control dogs. The majority of the dogs with SAS died suddenly (n=27); nine had died or been euthanased with signs of heart failure and eight were euthanased without clinical signs. Dogs with SAS had significantly narrower intramyocardial arteries (P<0.001) and more myocardial fibrosis (P<0.001) than control dogs. Male dogs and those with more severe hypertrophy had more vessel narrowing (P=0.02 and P=0.02, respectively), whereas dogs with dilated hearts had slightly less pronounced arterial thickening (P=0.01). Arterial narrowing was not related to age, but fibrosis increased with age (P=0.047). Dogs that died suddenly did not have a greater number of arterial changes than other dogs with SAS. This study suggests that most dogs with SAS have intramyocardial arterial narrowing and that the risk of dying suddenly is not significantly related to the overall degree of vessel obliteration.

  19. Radio-emitting narrow-line Seyfert 1 galaxies in the JVLA perspective

    NASA Astrophysics Data System (ADS)

    Berton, M.; Congiu, E.; Järvelä, E.; Antonucci, R.; Kharb, P.; Lister, M. L.; Tarchi, A.; Caccianiga, A.; Chen, S.; Foschini, L.; Lähteenmäki, A.; Richards, J. L.; Ciroi, S.; Cracco, V.; Frezzato, M.; La Mura, G.; Rafanelli, P.

    2018-06-01

    We report the first results of a survey on 74 narrow-line Seyfert 1 galaxies (NLS1s) carried out in 2015 with the Karl G. Jansky Very Large Array (JVLA) at 5 GHz in A-configuration. So far, this is the largest survey aimed to image the radio continuum of NLS1s. We produced radio maps in order to compare the general properties of three different samples of objects: radio-quiet NLS1s (RQNLS1s), steep-spectrum radio-loud NLS1s (S-NLS1s), and flat-spectrum radio-loud NLS1s (F-NLS1s). We find that the three classes correspond to different radio morphologies, with F-NLS1s being more compact, and RQNLS1s often showing diffuse emission on kpc scales. We also find that F-NLS1s might be low-luminosity and possibly young blazars, and that S-NLS1s are part of the parent population of F-NLS1s. Dedicated studies to RQNLS1s are needed to fully understand their role in the unification pictures. The reduced images (FITS files) are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/614/A87

  20. Growth of InN on Ge substrate by molecular beam epitaxy

    NASA Astrophysics Data System (ADS)

    Trybus, Elaissa; Namkoong, Gon; Henderson, Walter; Doolittle, W. Alan; Liu, Rong; Mei, Jin; Ponce, Fernando; Cheung, Maurice; Chen, Fei; Furis, Madalina; Cartwright, Alexander

    2005-06-01

    InN epitaxial growth on a (1 1 1)-oriented, Ga-doped germanium substrate using molecular beam epitaxy is described. X-ray diffraction and transmission electron microscopy investigations have shown that the InN epitaxial layer consists of a wurtzite structure, which has the epitaxial relationship of (0 0 0 1) InN∥(1 1 1) Ge. Transmission electron microscopy shows an intermediate layer at the interface between the InN/Ge substrate. Consistent with recent reports implying a narrow bandgap of InN [Phys. Stat Sol. B 229 (2002) R1, Appl. Phys. Lett. 80 (2002) 3967], a strong photoluminescence with peak energy of 0.69 eV at 15 K was observed for this InN epilayer, in contrast to the peak energy of 0.71 eV for Ga-doped Ge under the same measurement conditions.

  1. Aligned Silver Nanorod Array as SERS Substrates for Viral Sensing

    NASA Astrophysics Data System (ADS)

    Zhao, Yiping; Shanmukh, Saratchandra; Chaney, Stephen B.; Jones, Les; Dluhy, Richard A.; Tripp, Ralph A.

    2006-03-01

    The aligned silver nanorod array substrates prepared by the oblique angle deposition method are capable of providing extremely high enhancement factors (˜10^9) at near-infrared wavelengths (785 nm) for a standard reporter molecule 1,2 trans-(bis)pyridyl-ethene (BPE). The enhancement factor depends strongly on the length of the Ag nanorods, the substrate coating, as well as the polarization of the excitation laser beam. With the current optimum structure, we demonstrate that the detection limit for BPE can be lower than 0.1 fM. The applicability of this substrate to the detection of bioagents has been investigated by looking several viruses, such as Adenovirus, HIV, Rhinovirus and Respiratory Syncytial Virus (RSV), at low quantities (˜0.5uL). Different viruses have different fingerprint Raman spectrum. The detection of virus presented in infected cells has also been demonstrated.

  2. The Autism-Spectrum Quotient--Italian Version: A Cross-Cultural Confirmation of the Broader Autism Phenotype

    ERIC Educational Resources Information Center

    Ruta, Liliana; Mazzone, Domenico; Mazzone, Luigi; Wheelwright, Sally; Baron-Cohen, Simon

    2012-01-01

    The Autism Spectrum Quotient (AQ) has been used to define the "broader" (BAP), "medium" (MAP) and "narrow" autism phenotypes (NAP). We used a new Italian version of the AQ to test if difference on AQ scores and the distribution of BAP, MAP and NAP in autism parents (n = 245) versus control parents (n = 300) were…

  3. Spin filter for arbitrary spins by substrate engineering

    NASA Astrophysics Data System (ADS)

    Pal, Biplab; Römer, Rudolf A.; Chakrabarti, Arunava

    2016-08-01

    We design spin filters for particles with potentially arbitrary spin S≤ft(=1/2,1,3/2,\\ldots \\right) using a one-dimensional periodic chain of magnetic atoms as a quantum device. Describing the system within a tight-binding formalism we present an analytical method to unravel the analogy between a one-dimensional magnetic chain and a multi-strand ladder network. This analogy is crucial, and is subsequently exploited to engineer gaps in the energy spectrum by an appropriate choice of the magnetic substrate. We obtain an exact correlation between the magnitude of the spin of the incoming beam of particles and the magnetic moment of the substrate atoms in the chain desired for opening up of a spectral gap. Results of spin polarized transport, calculated within a transfer matrix formalism, are presented for particles having half-integer as well as higher spin states. We find that the chain can be made to act as a quantum device which opens a transmission window only for selected spin components over certain ranges of the Fermi energy, blocking them in the remaining part of the spectrum. The results appear to be robust even when the choice of the substrate atoms deviates substantially from the ideal situation, as verified by extending the ideas to the case of a ‘spin spiral’. Interestingly, the spin spiral geometry, apart from exhibiting the filtering effect, is also seen to act as a device flipping spins—an effect that can be monitored by an interplay of the system size and the period of the spiral. Our scheme is applicable to ultracold quantum gases, and might inspire future experiments in this direction.

  4. Ultra-narrow surface lattice resonances in plasmonic metamaterial arrays for biosensing applications.

    PubMed

    Danilov, Artem; Tselikov, Gleb; Wu, Fan; Kravets, Vasyl G; Ozerov, Igor; Bedu, Frederic; Grigorenko, Alexander N; Kabashin, Andrei V

    2018-05-01

    When excited over a periodic metamaterial lattice of gold nanoparticles (~ 100nm), localized plasmon resonances (LPR) can be coupled by a diffraction wave propagating along the array plane, which leads to a drastic narrowing of plasmon resonance lineshapes (down to a few nm full-width-at-half-maximum) and the generation of singularities of phase of reflected light. These phenomena look very promising for the improvement of performance of plasmonic biosensors, but conditions of implementation of such diffractively coupled plasmonic resonances, also referred to as plasmonic surface lattice resonances (PSLR), are not always compatible with biosensing arrangement implying the placement of the nanoparticles between a glass substrate and a sample medium (air, water). Here, we consider conditions of excitation and properties of PSLR over arrays of glass substrate-supported single and double Au nanoparticles (~ 100-200nm), arranged in a periodic metamaterial lattice, in direct and Attenuated Total Reflection (ATR) geometries, and assess their sensitivities to variations of refractive index (RI) of the adjacent sample dielectric medium. First, we identify medium (PSLR air , PSLR wat for air and water, respectively) and substrate (PSLR sub ) modes corresponding to the coupling of individual plasmon oscillations at medium- and substrate-related diffraction cut-off edges. We show that spectral sensitivity of medium modes to RI variations is determined by the lattice periodicity in both direct and ATR geometries (~ 320nm per RIU change in our case), while substrate mode demonstrates much lower sensitivity. We also show that phase sensitivity of PSLR can exceed 10 5 degrees of phase shift per RIU change and thus outperform the relevant parameter for all other plasmonic sensor counterparts. We finally demonstrate the applicability of surface lattice resonances in plasmonic metamaterial arrays to biosensing using standard streptavidin-biotin affinity model. Combining advantages of

  5. Thermokinetics of heterogeneous droplet nucleation on conically textured substrates.

    PubMed

    Singha, Sanat K; Das, Prasanta K; Maiti, Biswajit

    2015-11-28

    Within the framework of the classical theory of heterogeneous nucleation, a thermokinetic model is developed for line-tension-associated droplet nucleation on conical textures considering growth or shrinkage of the formed cluster due to both interfacial and peripheral monomer exchange and by considering different geometric configurations. Along with the principle of free energy extremization, Katz kinetic approach has been employed to study the effect of substrate conicity and wettability on the thermokinetics of heterogeneous water droplet nucleation. Not only the peripheral tension is found to have a considerable effect on the free energy barrier but also the substrate hydrophobicity and hydrophilicity are observed to switch over their roles between conical crest and trough for different growth rates of the droplet. Besides, the rate of nucleation increases and further promotes nucleation for negative peripheral tension as it diminishes the free energy barrier appreciably. Moreover, nucleation inhibition can be achievable for positive peripheral tension due to the enhancement of the free energy barrier. Analyzing all possible geometric configurations, the hydrophilic narrower conical cavity is found to be the most preferred nucleation site. These findings suggest a physical insight into the context of surface engineering for the promotion or the suppression of nucleation on real or engineered substrates.

  6. Narrow-linewidth Q-switched random distributed feedback fiber laser.

    PubMed

    Xu, Jiangming; Ye, Jun; Xiao, Hu; Leng, Jinyong; Wu, Jian; Zhang, Hanwei; Zhou, Pu

    2016-08-22

    A narrow-linewidth Q-switched random fiber laser (RFL) based on a half-opened cavity, which is realized by narrow-linewidth fiber Bragg grating (FBG) and a section of 3 km passive fiber, has been proposed and experimentally investigated. The narrow-linewidth lasing is generated by the spectral filtering of three FBGs with linewidth of 1.21 nm, 0.56 nm, and 0.12 nm, respectively. The Q switching of the distributed cavity is achieved by placing an acousto-optical modulator (AOM) between the FBG and the passive fiber. The maximal output powers of the narrow-linewidth RFLs with the three different FBGs are 0.54 W, 0.27 W, and 0.08 W, respectively. Furthermore, the repetition rates of the output pulses are 500 kHz, and the pulse durations are about 500 ns. The corresponding pulse energies are about 1.08 μJ, 0.54 μJ, and 0.16 μJ, accordingly. The linewidth of FBG can influence the output characteristics in full scale. The narrower the FBG, the higher the pump threshold; the lower the output power at the same pump level, the more serious the linewidth broadening; and thus the higher the proportion of the CW-ground exists in the output pulse trains. Thanks to the assistance of the band-pass filter (BPF), the proportion of the CW-ground of narrow-linewidth Q-switched RFL under the relative high-pump-low-output condition can be reduced effectively. The experimental results indicate that it is challenging to demonstrate a narrow-linewidth Q-switched RFL with high quality output. But further power scaling and linewidth narrowing is possible in the case of operating parameters, optimization efforts, and a more powerful pump source. To the best of our knowledge, this is the first demonstration of narrow-linewidth generation in a Q-switched RFL.

  7. Revisiting the Nucleotide and Aminoglycoside Substrate Specificity of the Bifunctional Aminoglycoside Acetyltransferase(6′)-Ie/Aminoglycoside Phosphotransferase(2″)-Ia Enzyme*

    PubMed Central

    Frase, Hilary; Toth, Marta; Vakulenko, Sergei B.

    2012-01-01

    The bifunctional aminoglycoside-modifying enzyme aminoglycoside acetyltransferase(6′)-Ie/aminoglycoside phosphotransferase(2″)-Ia, or AAC(6′)-Ie/APH(2″)-Ia, is the major source of aminoglycoside resistance in Gram-positive bacterial pathogens. In previous studies, using ATP as the cosubstrate, it was reported that the APH(2″)-Ia domain of this enzyme is unique among aminoglycoside phosphotransferases, having the ability to inactivate an unusually broad spectrum of aminoglycosides, including 4,6- and 4,5-disubstituted and atypical. We recently demonstrated that GTP, and not ATP, is the preferred cosubstrate of this enzyme. We now show, using competition assays between ATP and GTP, that GTP is the exclusive phosphate donor at intracellular nucleotide levels. In light of these findings, we reevaluated the substrate profile of the phosphotransferase domain of this clinically important enzyme. Steady-state kinetic characterization using the phosphate donor GTP demonstrates that AAC(6′)-Ie/APH(2″)-Ia phosphorylates 4,6-disubstituted aminoglycosides with high efficiency (kcat/Km = 105-107 m−1 s−1). Despite this proficiency, no resistance is conferred to some of these antibiotics by the enzyme in vivo. We now show that phosphorylation of 4,5-disubstituted and atypical aminoglycosides are negligible and thus these antibiotics are not substrates. Instead, these aminoglycosides tend to stimulate an intrinsic GTPase activity of the enzyme. Taken together, our data show that the bifunctional enzyme efficiently phosphorylates only 4,6-disubstituted antibiotics; however, phosphorylation does not necessarily result in bacterial resistance. Hence, the APH(2″)-Ia domain of the bifunctional AAC(6′)-Ie/APH(2″)-Ia enzyme is a bona fide GTP-dependent kinase with a narrow substrate profile, including only 4,6-disubstituted aminoglycosides. PMID:23115238

  8. Mapping the Substrate Binding Site of Phenylacetone Monooxygenase from Thermobifida fusca by Mutational Analysis▿†

    PubMed Central

    Dudek, Hanna M.; de Gonzalo, Gonzalo; Torres Pazmiño, Daniel E.; Stępniak, Piotr; Wyrwicz, Lucjan S.; Rychlewski, Leszek; Fraaije, Marco W.

    2011-01-01

    Baeyer-Villiger monooxygenases catalyze oxidations that are of interest for biocatalytic applications. Among these enzymes, phenylacetone monooxygenase (PAMO) from Thermobifida fusca is the only protein showing remarkable stability. While related enzymes often present a broad substrate scope, PAMO accepts only a limited number of substrates. Due to the absence of a substrate in the elucidated crystal structure of PAMO, the substrate binding site of this protein has not yet been defined. In this study, a structural model of cyclopentanone monooxygenase, which acts on a broad range of compounds, has been prepared and compared with the structure of PAMO. This revealed 15 amino acid positions in the active site of PAMO that may account for its relatively narrow substrate specificity. We designed and analyzed 30 single and multiple mutants in order to verify the role of these positions. Extensive substrate screening revealed several mutants that displayed increased activity and altered regio- or enantioselectivity in Baeyer-Villiger reactions and sulfoxidations. Further substrate profiling resulted in the identification of mutants with improved catalytic properties toward synthetically attractive compounds. Moreover, the thermostability of the mutants was not compromised in comparison to that of the wild-type enzyme. Our data demonstrate that the positions identified within the active site of PAMO, namely, V54, I67, Q152, and A435, contribute to the substrate specificity of this enzyme. These findings will aid in more dedicated and effective redesign of PAMO and related monooxygenases toward an expanded substrate scope. PMID:21724896

  9. Infants Experience Perceptual Narrowing for Nonprimate Faces

    ERIC Educational Resources Information Center

    Simpson, Elizabeth A.; Varga, Krisztina; Frick, Janet E.; Fragaszy, Dorothy

    2011-01-01

    Perceptual narrowing--a phenomenon in which perception is broad from birth, but narrows as a function of experience--has previously been tested with primate faces. In the first 6 months of life, infants can discriminate among individual human and monkey faces. Though the ability to discriminate monkey faces is lost after about 9 months, infants…

  10. The hard X-ray spectrum of NGC 5506 as seen by NuSTAR

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Matt, G.; Balokovi , M.; Marinucci, A.

    2015-01-14

    NuSTAR observed the bright Compton-thin, narrow-line Seyfert 1 galaxy, NGC 5506, for about 56 ks. In agreement with past observations, the spectrum is well fitted by a power law with Γ ~ 1.9, a distant reflection component and narrow ionized iron lines. A relativistically blurred reflection component is not required by the data. When an exponential high-energy cutoff is added to the power law, a value of 720more » $$+130\\atop{-190}$$ keV (90 percent confidence level) is found. Even allowing for systematic uncertainties, we find a 3σ lower limit to the high-energy cutoff of 350 keV, the highest lower limit to the cutoff energy found so far in an AGN by NuSTAR.« less

  11. Closed loop adaptive control of spectrum-producing step using neural networks

    DOEpatents

    Fu, Chi Yung

    1998-01-01

    Characteristics of the plasma in a plasma-based manufacturing process step are monitored directly and in real time by observing the spectrum which it produces. An artificial neural network analyzes the plasma spectrum and generates control signals to control one or more of the process input parameters in response to any deviation of the spectrum beyond a narrow range. In an embodiment, a plasma reaction chamber forms a plasma in response to input parameters such as gas flow, pressure and power. The chamber includes a window through which the electromagnetic spectrum produced by a plasma in the chamber, just above the subject surface, may be viewed. The spectrum is conducted to an optical spectrometer which measures the intensity of the incoming optical spectrum at different wavelengths. The output of optical spectrometer is provided to an analyzer which produces a plurality of error signals, each indicating whether a respective one of the input parameters to the chamber is to be increased or decreased. The microcontroller provides signals to control respective controls, but these lines are intercepted and first added to the error signals, before being provided to the controls for the chamber. The analyzer can include a neural network and an optional spectrum preprocessor to reduce background noise, as well as a comparator which compares the parameter values predicted by the neural network with a set of desired values provided by the microcontroller.

  12. Closed loop adaptive control of spectrum-producing step using neural networks

    DOEpatents

    Fu, C.Y.

    1998-11-24

    Characteristics of the plasma in a plasma-based manufacturing process step are monitored directly and in real time by observing the spectrum which it produces. An artificial neural network analyzes the plasma spectrum and generates control signals to control one or more of the process input parameters in response to any deviation of the spectrum beyond a narrow range. In an embodiment, a plasma reaction chamber forms a plasma in response to input parameters such as gas flow, pressure and power. The chamber includes a window through which the electromagnetic spectrum produced by a plasma in the chamber, just above the subject surface, may be viewed. The spectrum is conducted to an optical spectrometer which measures the intensity of the incoming optical spectrum at different wavelengths. The output of optical spectrometer is provided to an analyzer which produces a plurality of error signals, each indicating whether a respective one of the input parameters to the chamber is to be increased or decreased. The microcontroller provides signals to control respective controls, but these lines are intercepted and first added to the error signals, before being provided to the controls for the chamber. The analyzer can include a neural network and an optional spectrum preprocessor to reduce background noise, as well as a comparator which compares the parameter values predicted by the neural network with a set of desired values provided by the microcontroller. 7 figs.

  13. Motor-substrate interactions in mycoplasma motility explains non-Arrhenius temperature dependence.

    PubMed

    Chen, Jing; Neu, John; Miyata, Makoto; Oster, George

    2009-12-02

    Mycoplasmas exhibit a novel, substrate-dependent gliding motility that is driven by approximately 400 "leg" proteins. The legs interact with the substrate and transmit the forces generated by an assembly of ATPase motors. The velocity of the cell increases linearly by nearly 10-fold over a narrow temperature range of 10-40 degrees C. This corresponds to an Arrhenius factor that decreases from approximately 45 k(B)T at 10 degrees C to approximately 10 k(B)T at 40 degrees C. On the other hand, load-velocity curves at different temperatures extrapolate to nearly the same stall force, suggesting a temperature-insensitive force-generation mechanism near stall. In this article, we propose a leg-substrate interaction mechanism that explains the intriguing temperature sensitivity of this motility. The large Arrhenius factor at low temperature comes about from the addition of many smaller energy barriers arising from many substrate-binding sites at the distal end of the leg protein. The Arrhenius dependence attenuates at high temperature due to two factors: 1), the reduced effective multiplicity of energy barriers intrinsic to the multiple-site binding mechanism; and 2), the temperature-sensitive weakly facilitated leg release that curtails the power stroke. The model suggests an explanation for the similar steep, sub-Arrhenius temperature-velocity curves observed in many molecular motors, such as kinesin and myosin, wherein the temperature behavior is dominated not by the catalytic biochemistry, but by the motor-substrate interaction.

  14. Motor-Substrate Interactions in Mycoplasma Motility Explains Non-Arrhenius Temperature Dependence

    PubMed Central

    Chen, Jing; Neu, John; Miyata, Makoto; Oster, George

    2009-01-01

    Abstract Mycoplasmas exhibit a novel, substrate-dependent gliding motility that is driven by ∼400 “leg” proteins. The legs interact with the substrate and transmit the forces generated by an assembly of ATPase motors. The velocity of the cell increases linearly by nearly 10-fold over a narrow temperature range of 10–40°C. This corresponds to an Arrhenius factor that decreases from ∼45 kBT at 10°C to ∼10 kBT at 40°C. On the other hand, load-velocity curves at different temperatures extrapolate to nearly the same stall force, suggesting a temperature-insensitive force-generation mechanism near stall. In this article, we propose a leg-substrate interaction mechanism that explains the intriguing temperature sensitivity of this motility. The large Arrhenius factor at low temperature comes about from the addition of many smaller energy barriers arising from many substrate-binding sites at the distal end of the leg protein. The Arrhenius dependence attenuates at high temperature due to two factors: 1), the reduced effective multiplicity of energy barriers intrinsic to the multiple-site binding mechanism; and 2), the temperature-sensitive weakly facilitated leg release that curtails the power stroke. The model suggests an explanation for the similar steep, sub-Arrhenius temperature-velocity curves observed in many molecular motors, such as kinesin and myosin, wherein the temperature behavior is dominated not by the catalytic biochemistry, but by the motor-substrate interaction. PMID:19948122

  15. Athermal Silicon-on-insulator ring resonators by overlaying a polymer cladding on narrowed waveguides.

    PubMed

    Teng, Jie; Dumon, Pieter; Bogaerts, Wim; Zhang, Hongbo; Jian, Xigao; Han, Xiuyou; Zhao, Mingshan; Morthier, Geert; Baets, Roel

    2009-08-17

    Athermal silicon ring resonators are experimentally demonstrated by overlaying a polymer cladding on narrowed silicon wires. The ideal width to achieve athermal condition for the TE mode of 220 nm-height SOI waveguides is found to be around 350 nm. After overlaying a polymer layer, the wavelength temperature dependence of the silicon ring resonator is reduced to less than 5 pm/degrees C, almost eleven times less than that of normal silicon waveguides. The optical loss of a 350-nm bent waveguide (with a radius of 15 microm) is extracted from the ring transmission spectrum. The scattering loss is reduced to an acceptable level of about 50 dB/cm after overlaying a polymer cladding. (c) 2009 Optical Society of America

  16. Narrow plasmon resonances enabled by quasi-freestanding bilayer epitaxial graphene

    NASA Astrophysics Data System (ADS)

    Daniels, Kevin M.; Jadidi, M. Mehdi; Sushkov, Andrei B.; Nath, Anindya; Boyd, Anthony K.; Sridhara, Karthik; Drew, H. Dennis; Murphy, Thomas E.; Myers-Ward, Rachael L.; Gaskill, D. Kurt

    2017-06-01

    Exploiting the underdeveloped terahertz range (~1012-1013 Hz) of the electromagnetic spectrum could advance many scientific fields (e.g. medical imaging for the identification of tumors and other biological tissues, non-destructive evaluation of hidden objects or ultra-broadband communication). Despite the benefits of operating in this regime, generation, detection and manipulation have proven difficult, as few materials have functional interactions with THz radiation. In contrast, graphene supports resonances in the THz regime through structural confinement of surface plasmons, which can lead to enhanced absorption. In prior work, the achievable plasmon resonances in such structures have been limited by multiple electron scattering mechanisms (i.e. large carrier scattering rates) which greatly broaden the resonance (>100 cm-1 3 THz). We report the narrowest room temperature Drude response to-date, 30 cm-1 (0.87 THz), obtained using quasi-free standing bilayer epitaxial graphene (QFS BLG) synthesized on (0 0 0 1)6H-SiC. This narrow response is due to a 4-fold increase in carrier mobility and improved thickness and electronic uniformity of QFS BLG. Moreover, QFS BLG samples patterned into microribbons targeting 1.8-5.7 THz plasmon resonances also exhibit low scattering rates (37-53 cm-1). Due to the improved THz properties of QFS BLG, the effects of e-beam processing on carrier scattering rates was determined and we found that fabrication conditions can be tuned to minimize the impact on optoelectronic properties. In addition, electrostatic gating of patterned QFS BLG shows narrow band THz amplitude modulation. Taken together, these properties of QFS BLG should facilitate future development of THz optoelectronic devices for monochromatic applications.

  17. Structural basis for the substrate specificity of PepA from Streptococcus pneumoniae, a dodecameric tetrahedral protease.

    PubMed

    Kim, Doyoun; San, Boi Hoa; Moh, Sang Hyun; Park, Hyejin; Kim, Dong Young; Lee, Sangho; Kim, Kyeong Kyu

    2010-01-01

    Regulated cytosolic proteolysis is one of the key cellular processes ensuring proper functioning of a cell. M42 family proteases show a broad spectrum of substrate specificities, but the structural basis for such diversity of the substrate specificities is lagging behind biochemical data. Here we report the crystal structure of PepA from Streptococcus pneumoniae, a glutamyl aminopeptidase belonging to M42 family (SpPepA). We found that Arg-257 in the substrate binding pocket is strategically positioned so that Arg-257 can make electrostatic interactions with the acidic residue of a substrate at its N-terminus. Structural comparison of the substrate binding pocket of the M42 family proteases, along with the structure-based multiple sequence alignment, argues that the appropriate electrostatic interactions contribute to the selective substrate specificity of SpPepA. Copyright 2009 Elsevier Inc. All rights reserved.

  18. Subdigital setae of chameleon feet: friction-enhancing microstructures for a wide range of substrate roughness.

    PubMed

    Spinner, Marlene; Westhoff, Guido; Gorb, Stanislav N

    2014-06-27

    Hairy adhesive systems of microscopic setae with triangular flattened tips have evolved convergently in spiders, insects and arboreal lizards. The ventral sides of the feet and tails in chameleons are also covered with setae. However, chameleon setae feature strongly elongated narrow spatulae or fibrous tips. The friction enhancing function of these microstructures has so far only been demonstrated in contact with glass spheres. In the present study, the frictional properties of subdigital setae of Chamaeleo calyptratus were measured under normal forces in the physical range on plane substrates having different roughness. We showed that chameleon setae maximize friction on a wide range of substrate roughness. The highest friction was measured on asperities of 1 μm. However, our observations of the climbing ability of Ch. calyptratus on rods of different diameters revealed that also claws and grasping feet are additionally responsible for the force generation on various substrates during locomotion.

  19. Subdigital setae of chameleon feet: Friction-enhancing microstructures for a wide range of substrate roughness

    NASA Astrophysics Data System (ADS)

    Spinner, Marlene; Westhoff, Guido; Gorb, Stanislav N.

    2014-06-01

    Hairy adhesive systems of microscopic setae with triangular flattened tips have evolved convergently in spiders, insects and arboreal lizards. The ventral sides of the feet and tails in chameleons are also covered with setae. However, chameleon setae feature strongly elongated narrow spatulae or fibrous tips. The friction enhancing function of these microstructures has so far only been demonstrated in contact with glass spheres. In the present study, the frictional properties of subdigital setae of Chamaeleo calyptratus were measured under normal forces in the physical range on plane substrates having different roughness. We showed that chameleon setae maximize friction on a wide range of substrate roughness. The highest friction was measured on asperities of 1 μm. However, our observations of the climbing ability of Ch. calyptratus on rods of different diameters revealed that also claws and grasping feet are additionally responsible for the force generation on various substrates during locomotion.

  20. Light spectrum modifies the utilization pattern of energy sources in Pseudomonas sp. DR 5-09

    PubMed Central

    Rosberg, Anna Karin; Windstam, Sofia T.; Karlsson, Maria E.; Bergstrand, Karl-Johan; Khalil, Sammar; Wohanka, Walter

    2017-01-01

    Despite the overruling impact of light in the phyllosphere, little is known regarding the influence of light spectra on non-phototrophic bacteria colonizing the leaf surface. We developed an in vitro method to study phenotypic profile responses of bacterial pure cultures to different bands of the visible light spectrum using monochromatic (blue: 460 nm; red: 660 nm) and polychromatic (white: 350–990 nm) LEDs, by modification and optimization of a protocol for the Phenotype MicroArray™ technique (Biolog Inc., CA, USA). The new protocol revealed high reproducibility of substrate utilization under all conditions tested. Challenging the non-phototrophic bacterium Pseudomonas sp. DR 5–09 with white, blue, and red light demonstrated that all light treatments affected the respiratory profile differently, with blue LED having the most decisive impact on substrate utilization by impairing respiration of 140 substrates. The respiratory activity was decreased on 23 and 42 substrates under red and white LEDs, respectively, while utilization of one, 16, and 20 substrates increased in the presence of red, blue, and white LEDs, respectively. Interestingly, on four substrates contrasting utilization patterns were found when the bacterium was exposed to different light spectra. Although non-phototrophic bacteria do not rely directly on light as an energy source, Pseudomonas sp. DR 5–09 changed its respiratory activity on various substrates differently when exposed to different lights. Thus, ability to sense and distinguish between different wavelengths even within the visible light spectrum must exist, and leads to differential regulation of substrate usage. With these results, we hypothesize that different light spectra might be a hitherto neglected key stimulus for changes in microbial lifestyle and habits of substrate usage by non-phototrophic phyllospheric microbiota, and thus might essentially stratify leaf microbiota composition and diversity. PMID:29267321

  1. Light spectrum modifies the utilization pattern of energy sources in Pseudomonas sp. DR 5-09.

    PubMed

    Gharaie, Samareh; Vaas, Lea A I; Rosberg, Anna Karin; Windstam, Sofia T; Karlsson, Maria E; Bergstrand, Karl-Johan; Khalil, Sammar; Wohanka, Walter; Alsanius, Beatrix W

    2017-01-01

    Despite the overruling impact of light in the phyllosphere, little is known regarding the influence of light spectra on non-phototrophic bacteria colonizing the leaf surface. We developed an in vitro method to study phenotypic profile responses of bacterial pure cultures to different bands of the visible light spectrum using monochromatic (blue: 460 nm; red: 660 nm) and polychromatic (white: 350-990 nm) LEDs, by modification and optimization of a protocol for the Phenotype MicroArray™ technique (Biolog Inc., CA, USA). The new protocol revealed high reproducibility of substrate utilization under all conditions tested. Challenging the non-phototrophic bacterium Pseudomonas sp. DR 5-09 with white, blue, and red light demonstrated that all light treatments affected the respiratory profile differently, with blue LED having the most decisive impact on substrate utilization by impairing respiration of 140 substrates. The respiratory activity was decreased on 23 and 42 substrates under red and white LEDs, respectively, while utilization of one, 16, and 20 substrates increased in the presence of red, blue, and white LEDs, respectively. Interestingly, on four substrates contrasting utilization patterns were found when the bacterium was exposed to different light spectra. Although non-phototrophic bacteria do not rely directly on light as an energy source, Pseudomonas sp. DR 5-09 changed its respiratory activity on various substrates differently when exposed to different lights. Thus, ability to sense and distinguish between different wavelengths even within the visible light spectrum must exist, and leads to differential regulation of substrate usage. With these results, we hypothesize that different light spectra might be a hitherto neglected key stimulus for changes in microbial lifestyle and habits of substrate usage by non-phototrophic phyllospheric microbiota, and thus might essentially stratify leaf microbiota composition and diversity.

  2. Ga/1-x/Al/x/As LED structures grown on GaP substrates.

    NASA Technical Reports Server (NTRS)

    Woodall, J. M.; Potemski, R. M.; Blum, S. E.; Lynch, R.

    1972-01-01

    Ga(1-x)Al(x)As light-emitting diode structures have been grown on GaP substrates by the liquid-phase-epitaxial method. In spite of the large differences in lattice constants and thermal-expansion coefficients, room-temperature efficiencies up to 5.5% in air have been observed for a peak emission of 8500 A. Using undoped GaP substrates, which are transparent to the infrared and red portions of the spectrum, thin structures of Ga(1-x)Al(x)As with large external efficiencies can now be made.

  3. A Neural Substrate for Atypical Low-Level Visual Processing in Autism Spectrum Disorder

    ERIC Educational Resources Information Center

    Vandenbroucke, Myriam W. G.; Scholte, H. Steven; van Engeland, Herman; Lamme, Victor A. F.; Kemner, Chantal

    2008-01-01

    An important characteristic of autism spectrum disorder (ASD) is increased visual detail perception. Yet, there is no standing neurobiological explanation for this aspect of the disorder. We show evidence from EEG data, from 31 control subjects (three females) and 13 subjects (two females) aged 16-28 years, for a specific impairment in object…

  4. Narrow-Line Seyfert 1 Galaxies

    NASA Technical Reports Server (NTRS)

    Leighly, Karen M.

    2000-01-01

    The primary work during this year has been the analysis and interpretation of our HST spectra from two extreme Narrow-line Seyfert 1 galaxies (NLS1s) Infrared Astronomy Satellite (IRAS) 13224-3809 and 1H 0707-495. This work has been presented as an invited talk at the workshop entitled "Observational and theoretical progress in the Study of Narrow-line Seyfert 1 Galaxies" held in Bad Honnef, Germany December 8-11, as a contributed talk at the January 2000 AAS meeting in Atlanta, Georgia, and as a contributed talk at the workshop "Probing the Physics of Active Galactic Nuclei by Multiwavelength Monitoring" held at Goddard Space Flight Center June 20-22, 2000.

  5. Disrupted prediction errors index social deficits in autism spectrum disorder

    PubMed Central

    Balsters, Joshua H; Apps, Matthew A J; Bolis, Dimitris; Lehner, Rea; Gallagher, Louise; Wenderoth, Nicole

    2017-01-01

    Abstract Social deficits are a core symptom of autism spectrum disorder; however, the perturbed neural mechanisms underpinning these deficits remain unclear. It has been suggested that social prediction errors—coding discrepancies between the predicted and actual outcome of another’s decisions—might play a crucial role in processing social information. While the gyral surface of the anterior cingulate cortex signalled social prediction errors in typically developing individuals, this crucial social signal was altered in individuals with autism spectrum disorder. Importantly, the degree to which social prediction error signalling was aberrant correlated with diagnostic measures of social deficits. Effective connectivity analyses further revealed that, in typically developing individuals but not in autism spectrum disorder, the magnitude of social prediction errors was driven by input from the ventromedial prefrontal cortex. These data provide a novel insight into the neural substrates underlying autism spectrum disorder social symptom severity, and further research into the gyral surface of the anterior cingulate cortex and ventromedial prefrontal cortex could provide more targeted therapies to help ameliorate social deficits in autism spectrum disorder. PMID:28031223

  6. Monolayer Boron Nitride Substrate Interactions with Graphene Under In-Plane and Perpendicular Strains: A First-Principles Study

    NASA Astrophysics Data System (ADS)

    Behzad, Somayeh

    2018-04-01

    Effects of strain on the electronic and optical properties of graphene on monolayer boron nitride (BN) substrate are investigated using first-principle calculations based on density functional theory. Strain-free graphene/BN has a small band gap of 97 meV at the K point. The magnitude of band gap increases with in-plane biaxial strain while it decreases with the perpendicular uniaxial strain. The ɛ2 (ω ) spectrum of graphene/BN bilayer for parallel polarization shows red and blue shifts by applying the in-plane tensile and compressive strains, respectively. Also the positions of peaks in the ɛ2 (ω ) spectrum are not significantly changed under perpendicular strain. The calculated results indicate that graphene on the BN substrate has great potential in microelectronic and optoelectronic applications.

  7. Improving surface-enhanced Raman scattering effect using gold-coated hierarchical polystyrene bead substrates modified with postgrowth microwave treatment.

    PubMed

    Yuen, Clement; Zheng, Wei; Huang, Zhiwei

    2008-01-01

    We report a novel postgrowth microwave heating implementation by selectively modifying hierarchical polystyrene (PS) bead substrates coated with gold (Au) films to effectively improve the surface-enhanced Raman scattering (SERS) effect on the analytes. The SERS signal of probe molecule rhodamine 6G (Rh 6G) on the microwave-treated Au-PS substrates can be improved by 10-fold, while the detection limit of Rh 6G in concentration can be enhanced by two orders of magnitude compared to the as-growth substrates. The high-quality SERS spectrum of saliva can also be acquired using the modified substrates, demonstrating the potential for the realization of the high-performance SERS substrates for biomedical applications.

  8. Narrow phase-dependent features in X-ray dim isolated neutron stars: a new detection and upper limits

    NASA Astrophysics Data System (ADS)

    Borghese, A.; Rea, N.; Coti Zelati, F.; Tiengo, A.; Turolla, R.; Zane, S.

    2017-07-01

    We report on the results of a detailed phase-resolved spectroscopy of archival XMM-Newton observations of X-ray dim isolated neutron stars (XDINSs). Our analysis revealed a narrow and phase-variable absorption feature in the X-ray spectrum of RX J1308.6+2127. The feature has an energy of ˜740 eV and an equivalent width of ˜15 eV. It is detected only in ˜1/5 of the phase cycle, and appears to be present for the entire timespan covered by the observations (2001 December to 2007 June). The strong dependence on the pulsar rotation and the narrow width suggest that the feature is likely due to resonant cyclotron absorption/scattering in a confined high-B structure close to the stellar surface. Assuming a proton cyclotron line, the magnetic field strength in the loop is Bloop ˜ 1.7 × 1014 G, about a factor of ˜5 higher than the surface dipolar magnetic field (Bsurf ˜ 3.4 × 1013 G). This feature is similar to that recently detected in another XDINS, RX J0720.4-3125, showing (as expected by theoretical simulations) that small-scale magnetic loops close to the surface might be common to many highly magnetic neutron stars (although difficult to detect with current X-ray instruments). Furthermore, we investigated the available XMM-Newton data of all XDINSs in search for similar narrow phase-dependent features, but could derive only upper limits for all the other sources.

  9. 2. Photocopied July 1971 from photostat Jordan Narrows Folder #1, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Photocopied July 1971 from photostat Jordan Narrows Folder #1, Engineering Department, Utah Power and Light Co., Salt Lake City, Utah. JORDAN NARROWS STATION. PLAN AND SECTION. - Salt Lake City Water & Electrical Power Company, Jordan Narrows Hydroelectric Plant, Jordan River, Riverton, Salt Lake County, UT

  10. Novel narrow-host-range vectors for direct cloning of foreign DNA in Pseudomonas.

    PubMed

    Boivin, R; Bellemare, G; Dion, P

    1994-01-01

    Narrow-host-range vectors, based on an indigenous replicon and containing a multiple cloning site, have been constructed in a Pseudomonas host capable of growth on unusual substrates. The new cloning vectors yield sufficient amounts of DNA for preparative purposes and belong to an incompatibility group different from that of the incP and incQ broad-host-range vectors. One of these vectors, named pDB47F, was used to clone, directly in Pseudomonas, DNA fragments from Agrobacterium, Pseudomonas, and Rhizobium. A clone containing Agrobacterium and KmR gene sequences was transformed with a higher efficiency than an RSF1010-derived vector (by as much as 1250-fold) in four out of five Pseudomonas strains tested. The considerable efficiency obtained with this system makes possible the direct cloning and phenotypic selection of foreign DNA in Pseudomonas.

  11. An enhanced narrow-band imaging method for the microvessel detection

    NASA Astrophysics Data System (ADS)

    Yu, Feng; Song, Enmin; Liu, Hong; Wan, Youming; Zhu, Jun; Hung, Chih-Cheng

    2018-02-01

    A medical endoscope system combined with the narrow-band imaging (NBI), has been shown to be a superior diagnostic tool for early cancer detection. The NBI can reveal the morphologic changes of microvessels in the superficial cancer. In order to improve the conspicuousness of microvessel texture, we propose an enhanced NBI method to improve the conspicuousness of endoscopic images. To obtain the more conspicuous narrow-band images, we use the edge operator to extract the edge information of the narrow-band blue and green images, and give a weight to the extracted edges. Then, the weighted edges are fused with the narrow-band blue and green images. Finally, the displayed endoscopic images are reconstructed with the enhanced narrow-band images. In addition, we evaluate the performance of enhanced narrow-band images with different edge operators. Experimental results indicate that the Sobel and Canny operators achieve the best performance of all. Compared with traditional NBI method of Olympus company, our proposed method has more conspicuous texture of microvessel.

  12. Thermal tuning On narrow linewidth fiber laser

    NASA Astrophysics Data System (ADS)

    Han, Peiqi; Liu, Tianshan; Gao, Xincun; Ren, Shiwei

    2010-10-01

    At present, people have been dedicated to high-speed and large-capacity optical fiber communication system. Studies have been shown that optical wavelength division multiplexing (WDM) technology is an effective means of communication to increase the channel capacity. Tunable lasers have very important applications in high-speed, largecapacity optical communications, and distributed sensing, it can provide narrow linewidth and tunable laser for highspeed optical communication. As the erbium-doped fiber amplifier has a large gain bandwidth, the erbium-doped fiber laser can be achieved lasing wavelength tunable by adding a tunable filter components, so tunable filter device is the key components in tunable fiber laser.At present, fiber laser wavelength is tuned by PZT, if thermal wavelength tuning is combined with PZT, a broader range of wavelength tuning is appearance . Erbium-doped fiber laser is used in the experiments,the main research is the physical characteristics of fiber grating temperature-dependent relationship and the fiber grating laser wavelength effects. It is found that the fiber laser wavelength changes continuously with temperature, tracking several temperature points observed the self-heterodyne spectrum and found that the changes in spectra of the 3dB bandwidth of less than 1kHz, and therefore the fiber laser with election-mode fiber Bragg grating shows excellent spectral properties and wavelength stability.

  13. Associations between narrow angle and adult anthropometry: the Liwan Eye Study.

    PubMed

    Jiang, Yuzhen; He, Mingguang; Friedman, David S; Khawaja, Anthony P; Lee, Pak Sang; Nolan, Winifred P; Yin, Qiuxia; Foster, Paul J

    2014-06-01

    To assess the associations between narrow angle and adult anthropometry. Chinese adults aged 50 years and older were recruited from a population-based survey in the Liwan District of Guangzhou, China. Narrow angle was defined as the posterior trabecular meshwork not visible under static gonioscopy in at least three quadrants (i.e. a circumference of at least 270°). Logistic regression models were used to examine the associations between narrow angle and anthropomorphic measures (height, weight and body mass index, BMI). Among the 912 participants, lower weight, shorter height, and lower BMI were significantly associated with narrower angle width (tests for trend: mean angle width in degrees vs weight p < 0.001; vs height p < 0.001; vs BMI p = 0.012). In univariate analyses, shorter height, lower weight and lower BMI were all significantly associated with greater odds of narrow angle. The crude association between height and narrow angle was largely attributable to a stronger association with age and sex. Lower BMI and weight remained significantly associated with narrow angle after adjustment for height, age, sex, axial ocular biometric measures and education. In analyses stratified by sex, the association between BMI and narrow angle was only observed in women. Lower BMI and weight were associated with significantly greater odds of narrow angle after adjusting for age, education, axial ocular biometric measures and height. The odds of narrow angle increased 7% per 1 unit decrease in BMI. This association was most evident in women.

  14. Surface-enhanced Raman spectroscopy with Au-nanoparticle substrate fabricated by using femtosecond pulse.

    PubMed

    Zhang, Wending; Li, Cheng; Gao, Kun; Lu, Fanfan; Liu, Min; Li, Xin; Zhang, Lu; Mao, Dong; Gao, Feng; Huang, Ligang; Mei, Ting; Zhao, Jianlin

    2018-05-18

    Au-nanoparticle (Au-NP) substrates for surface-enhanced Raman spectroscopy (SERS) were fabricated by grid-like scanning a Au-film using a femtosecond pulse. The Au-NPs were directly deposited on the Au-film surface due to the scanning process. The experimentally obtained Au-NPs presented local surface plasmon resonance effect in the visible spectral range, as verified by finite difference time domain simulations and measured reflection spectrum. The SERS experiment using the Au-NP substrates exhibited high activity and excellent substrate reproducibility and stability, and a clearly present Raman spectra of target analytes, e.g. Rhodamine-6G, Rhodamine-B and Malachite green, with concentrations down to 10 -9 M. This work presents an effective approach to producing Au-NP SERS substrates with advantages in activity, reproducibility and stability, which could be used in a wide variety of practical applications for trace amount detection.

  15. Surface-enhanced Raman spectroscopy with Au-nanoparticle substrate fabricated by using femtosecond pulse

    NASA Astrophysics Data System (ADS)

    Zhang, Wending; Li, Cheng; Gao, Kun; Lu, Fanfan; Liu, Min; Li, Xin; Zhang, Lu; Mao, Dong; Gao, Feng; Huang, Ligang; Mei, Ting; Zhao, Jianlin

    2018-05-01

    Au-nanoparticle (Au-NP) substrates for surface-enhanced Raman spectroscopy (SERS) were fabricated by grid-like scanning a Au-film using a femtosecond pulse. The Au-NPs were directly deposited on the Au-film surface due to the scanning process. The experimentally obtained Au-NPs presented local surface plasmon resonance effect in the visible spectral range, as verified by finite difference time domain simulations and measured reflection spectrum. The SERS experiment using the Au-NP substrates exhibited high activity and excellent substrate reproducibility and stability, and a clearly present Raman spectra of target analytes, e.g. Rhodamine-6G, Rhodamine-B and Malachite green, with concentrations down to 10‑9 M. This work presents an effective approach to producing Au-NP SERS substrates with advantages in activity, reproducibility and stability, which could be used in a wide variety of practical applications for trace amount detection.

  16. Hot Wax Sweeps Debris From Narrow Passages

    NASA Technical Reports Server (NTRS)

    Ricklefs, Steven K.

    1990-01-01

    Safe and effective technique for removal of debris and contaminants from narrow passages involves entrainment of undesired material in thermoplastic casting material. Semisolid wax slightly below melting temperature pushed along passage by pressurized nitrogen to remove debris. Devised to clean out fuel passages in main combustion chamber of Space Shuttle main engine. Also applied to narrow, intricate passages in internal-combustion-engine blocks, carburetors, injection molds, and other complicated parts.

  17. Experimental and theoretical study of the buckling of narrow thin plates on an elastic foundation under compression

    NASA Astrophysics Data System (ADS)

    Kurguzov, V. D.; Demeshkin, A. G.

    2016-05-01

    The paper describes the processes of elastic deformation of thin films under mechanical loading. The film is modeled longitudinally by a compressed plate arranged on an elastic foundation. A computer model of the buckling of the narrow thin plate with a delamination portion located on an elastic foundation is constructed. This paper also touches upon the supercritical behavior of the plate-substrate system. The experiments on the axial compression of a metal strip adhered to a rubber plate are performed, and 2 to 7 buckling modes are obtained therein. The critical loads and buckling modes obtained in the numerical calculations are compared with the experimental data. It is shown that there is the possibility of progressive delamination of the metal plate from the foundation if the critical load is exceeded. It is found that the use of the proposed approach, which, in contrast to other approaches, accounts for the elastic deformation of the substrate, causes the dependence between the critical bending stress and the stiffness of the foundation.

  18. Subdigital setae of chameleon feet: Friction-enhancing microstructures for a wide range of substrate roughness

    PubMed Central

    Spinner, Marlene; Westhoff, Guido; Gorb, Stanislav N.

    2014-01-01

    Hairy adhesive systems of microscopic setae with triangular flattened tips have evolved convergently in spiders, insects and arboreal lizards. The ventral sides of the feet and tails in chameleons are also covered with setae. However, chameleon setae feature strongly elongated narrow spatulae or fibrous tips. The friction enhancing function of these microstructures has so far only been demonstrated in contact with glass spheres. In the present study, the frictional properties of subdigital setae of Chamaeleo calyptratus were measured under normal forces in the physical range on plane substrates having different roughness. We showed that chameleon setae maximize friction on a wide range of substrate roughness. The highest friction was measured on asperities of 1 μm. However, our observations of the climbing ability of Ch. calyptratus on rods of different diameters revealed that also claws and grasping feet are additionally responsible for the force generation on various substrates during locomotion. PMID:24970387

  19. Design of N-acyl homoserine lactonase with high substrate specificity by a rational approach.

    PubMed

    Kyeong, Hyun-Ho; Kim, Jin-Hyun; Kim, Hak-Sung

    2015-06-01

    N-Acyl homoserine lactone (AHL) is a major quorum-sensing signaling molecule in many bacterial species. Quorum-quenching (QQ) enzymes, which degrade such signaling molecules, have attracted much attention as an approach to controlling and preventing bacterial virulence and pathogenesis. However, naturally occurring QQ enzymes show a broad substrate spectrum, raising the concern of unintentionally attenuating beneficial effects by symbiotic bacteria. Here we report the rational design of acyl homoserine lactonase with high substrate specificity. Through docking analysis, we identified three key residues which play a key role in the substrate preference of the enzyme. The key residues were changed in a way that increases hydrophobic contact with a substrate having a short acyl chain (C4-AHL) while generating steric clashes with that containing a long acyl chain (C12-AHL). The resulting mutants exhibited a significantly shifted preference toward a substrate with a short acyl chain. Molecular dynamics simulations suggested that the mutations affect the behavior of a flexible loop, allowing tighter binding of a substrate with a short acyl chain.

  20. Turboprop and rotary-wing aircraft flight parameter estimation using both narrow-band and broadband passive acoustic signal-processing methods.

    PubMed

    Ferguson, B G; Lo, K W

    2000-10-01

    Flight parameter estimation methods for an airborne acoustic source can be divided into two categories, depending on whether the narrow-band lines or the broadband component of the received signal spectrum is processed to estimate the flight parameters. This paper provides a common framework for the formulation and test of two flight parameter estimation methods: one narrow band, the other broadband. The performances of the two methods are evaluated by applying them to the same acoustic data set, which is recorded by a planar array of passive acoustic sensors during multiple transits of a turboprop fixed-wing aircraft and two types of rotary-wing aircraft. The narrow-band method, which is based on a kinematic model that assumes the source travels in a straight line at constant speed and altitude, requires time-frequency analysis of the acoustic signal received by a single sensor during each aircraft transit. The broadband method is based on the same kinematic model, but requires observing the temporal variation of the differential time of arrival of the acoustic signal at each pair of sensors that comprises the planar array. Generalized cross correlation of each pair of sensor outputs using a cross-spectral phase transform prefilter provides instantaneous estimates of the differential times of arrival of the signal as the acoustic wavefront traverses the array.

  1. Application of Mobility Spectrum Analysis to Modern Multi-layered IR Device Material

    NASA Astrophysics Data System (ADS)

    Brown, Alexander Earl

    Modern detector materials used for infrared (IR) imaging purposes contain complex multi-layered architectures, making more robust characterization techniques necessary. In order to determine mutli-carrier transport properties in the presence of mixed conduction, variable-field Hall characterization can be performed and then analyzed using mobility spectrum analysis to extract parameters of interest. Transport parameters are expected to aid in modeling and simulation of materials and can be used in optimization of particular problem areas. The performances of infrared devices ultimately depend on transport mechanisms, so an accurate determination becomes paramount. This work focuses on the characterization of two materials at the forefront of IR detectors; incumbent, tried and true, HgCdTe technologies and emergent III-V based superlattice structures holding much promise for future detector purposes. Ex-situ doped long-wave planar devices and in-situ doped mid-wave dual-layer heterojunctions (P+/n architecture) HgCdTe structures are explored with regards to substrate choice, namely lattice-matched CdZnTe and lattice-mismatched Si or GaAs. A detailed study of scattering mechanisms reveal that growth on lattice-mismatched substrates leads to dislocation scattering limited mobility at low temperature, correlating with extrinsically limited minority carrier lifetime and excesses diode tunneling current, resulting in overall lower performance. Mobility spectrum analysis proves to be an effective diagnostic on performance as well as providing insight in surface, substrate-interface, and minority carrier transport. Two main issues limiting performance of III-V based superlattices are addressed; high residual doping backgrounds and surface passivation. Mobility spectrum analysis proves to be a reliable method of determining background doping levels. Modest improvements are obtained via post-growth thermal annealing, but results suggest future efforts should be placed upon

  2. Fracture strength and probability of survival of narrow and extra-narrow dental implants after fatigue testing: In vitro and in silico analysis.

    PubMed

    Bordin, Dimorvan; Bergamo, Edmara T P; Fardin, Vinicius P; Coelho, Paulo G; Bonfante, Estevam A

    2017-07-01

    To assess the probability of survival (reliability) and failure modes of narrow implants with different diameters. For fatigue testing, 42 implants with the same macrogeometry and internal conical connection were divided, according to diameter, as follows: narrow (Ø3.3×10mm) and extra-narrow (Ø2.9×10mm) (21 per group). Identical abutments were torqued to the implants and standardized maxillary incisor crowns were cemented and subjected to step-stress accelerated life testing (SSALT) in water. The use-level probability Weibull curves, and reliability for a mission of 50,000 and 100,000 cycles at 50N, 100, 150 and 180N were calculated. For the finite element analysis (FEA), two virtual models, simulating the samples tested in fatigue, were constructed. Loading at 50N and 100N were applied 30° off-axis at the crown. The von-Mises stress was calculated for implant and abutment. The beta (β) values were: 0.67 for narrow and 1.32 for extra-narrow implants, indicating that failure rates did not increase with fatigue in the former, but more likely were associated with damage accumulation and wear-out failures in the latter. Both groups showed high reliability (up to 97.5%) at 50 and 100N. A decreased reliability was observed for both groups at 150 and 180N (ranging from 0 to 82.3%), but no significant difference was observed between groups. Failure predominantly involved abutment fracture for both groups. FEA at 50N-load, Ø3.3mm showed higher von-Mises stress for abutment (7.75%) and implant (2%) when compared to the Ø2.9mm. There was no significant difference between narrow and extra-narrow implants regarding probability of survival. The failure mode was similar for both groups, restricted to abutment fracture. Copyright © 2017 Elsevier Ltd. All rights reserved.

  3. The study of VOPc thin film transistors on modified substrates

    NASA Astrophysics Data System (ADS)

    Song, De; Xu, Qi; Cheng, Hongcang; Li, Bao-zeng; Shang, Yubin

    2018-02-01

    The vanadyl phthalocyanine (VOPc) organic thin film transistors (OTFTs) were fabricated on the various organosilane self-assembled monolayer (SAM) modified substrates. And the effect of the surface properties on the performance of these transistors was studied. The atomic force morphologies and X-ray diffraction (XRD) spectrums of vanadyl phthalocyanine films on different SAM-modified surfaces were studied. They reveal that the terminal functional groups of organosilane affect the growth of VOPc film and device performance. The VOPc film on octadecyltrichlorosilane (OTS) modified substrate has larger crystal size and effective crystal thickness than those on phenyltrichlorosilane (PTS), 1H,1H,2H,2H-Perfluorodec-yltrichlorosilane (FDTS) as well as non-modified substrate, which contributes the mobility of corresponding device several and several dozen times relative to other ones. The effective crystal thickness and crystal grain size of VOPc film on PTS is between that on OTS treated and that on non-modified substrate due to the stronger attractive force between VOPc and SiO2. The VOPc films' performance and effective crystal thickness on FDTS treated are worse than that on PTS due to the existents of attractive force between -CF3 and VOPc.

  4. Associations between Narrow Angle and Adult Anthropometry: The Liwan Eye Study

    PubMed Central

    Jiang, Yuzhen; He, Mingguang; Friedman, David S.; Khawaja, Anthony P.; Lee, Pak Sang; Nolan, Winifred P.; Yin, Qiuxia; Foster, Paul J.

    2015-01-01

    Purpose To assess the associations between narrow angle and adult anthropometry. Methods Chinese adults aged 50 years and older were recruited from a population-based survey in the Liwan District of Guangzhou, China. Narrow angle was defined as the posterior trabecular meshwork not visible under static gonioscopy in at least three quadrants (i.e. a circumference of at least 270°). Logistic regression models were used to examine the associations between narrow angle and anthropomorphic measures (height, weight and body mass index, BMI). Results Among the 912 participants, lower weight, shorter height, and lower BMI were significantly associated with narrower angle width (tests for trend: mean angle width in degrees vs weight p<0.001; vs height p<0.001; vs BMI p = 0.012). In univariate analyses, shorter height, lower weight and lower BMI were all significantly associated with greater odds of narrow angle. The crude association between height and narrow angle was largely attributable to a stronger association with age and sex. Lower BMI and weight remained significantly associated with narrow angle after adjustment for height, age, sex, axial ocular biometric measures and education. In analyses stratified by sex, the association between BMI and narrow angle was only observed in women. Conclusion Lower BMI and weight were associated with significantly greater odds of narrow angle after adjusting for age, education, axial ocular biometric measures and height. The odds of narrow angle increased 7% per 1 unit decrease in BMI. This association was most evident in women. PMID:24707840

  5. Ultra-thin narrow-band, complementary narrow-band, and dual-band metamaterial absorbers for applications in the THz regime

    NASA Astrophysics Data System (ADS)

    Astorino, Maria Denise; Frezza, Fabrizio; Tedeschi, Nicola

    2017-02-01

    In this paper, ultra-thin narrow-band, complementary narrow-band, and dual-band metamaterial absorbers (MMAs), exploiting the same electric ring resonator configuration, are investigated at normal and oblique incidence for both transverse electric (TE) and transverse magnetic (TM) polarizations, and with different physical properties in the THz regime. In the analysis of the ultra-thin narrow-band MMA, the limit of applicability of the transmission line model has been overcome with the introduction of a capacitance which considers the z component of the electric field. These absorbing structures have shown a wide angular response and a polarization-insensitive behavior due to the introduction of a conducting ground plane and to the four-fold rotational symmetry of the resonant elements around the propagation axis. We have adopted a retrieval procedure to extract the effective electromagnetic parameters of the proposed MMAs and we have compared the simulated and analytical results through the interference theory.

  6. Narrow-band generation in random distributed feedback fiber laser.

    PubMed

    Sugavanam, Srikanth; Tarasov, Nikita; Shu, Xuewen; Churkin, Dmitry V

    2013-07-15

    Narrow-band emission of spectral width down to ~0.05 nm line-width is achieved in the random distributed feedback fiber laser employing narrow-band fiber Bragg grating or fiber Fabry-Perot interferometer filters. The observed line-width is ~10 times less than line-width of other demonstrated up to date random distributed feedback fiber lasers. The random DFB laser with Fabry-Perot interferometer filter provides simultaneously multi-wavelength and narrow-band (within each line) generation with possibility of further wavelength tuning.

  7. Low-temperature synthesis of single-walled carbon nanotubes with a narrow diameter distribution using size-classified catalyst nanoparticles

    NASA Astrophysics Data System (ADS)

    Kondo, Daiyu; Sato, Shintaro; Awano, Yuji

    2006-05-01

    Single-walled carbon nanotubes (SWNTs) with a narrow diameter distribution have been synthesized by hot-filament chemical vapor deposition using acetylene at 590 °C. Iron nanoparticles with diameters of 1.6, 2.0, 2.5, 5.0 and 10 nm (standard deviation: ≈10%) obtained with a differential mobility analyzer were used as a catalyst without any supporting materials on a substrate. SWNTs were obtained from 2.0 nm or smaller particles. The ratio of G band to D band in Raman spectra was as high as 35 without purification, indicating that high-quality SWNTs were synthesized. The SWNT diameters correlated with the particle diameters, demonstrating diameter-controlled SWNT growth.

  8. Nickel enhanced graphene growth directly on dielectric substrates by molecular beam epitaxy

    NASA Astrophysics Data System (ADS)

    Wofford, Joseph M.; Speck, Florian; Seyller, Thomas; Lopes, Joao Marcelo J.; Riechert, Henning

    2016-07-01

    The efficacy of Ni as a surfactant to improve the crystalline quality of graphene grown directly on dielectric Al2O3(0001) substrates by molecular beam epitaxy is examined. Simultaneously exposing the substrate to a Ni flux throughout C deposition at 950 °C led to improved charge carrier mobility and a Raman spectrum indicating less structural disorder in the resulting nanocrystalline graphene film. X-ray photoelectron spectroscopy confirmed that no residual Ni could be detected in the film and showed a decrease in the intensity of the defect-related component of the C1s level. Similar improvements were not observed when a lower substrate temperature (850 °C) was used. A close examination of the Raman spectra suggests that Ni reduces the concentration of lattice vacancies in the film, possibly by catalytically assisting adatom incorporation.

  9. Vision and spectroscopic sensing for joint tracing in narrow gap laser butt welding

    NASA Astrophysics Data System (ADS)

    Nilsen, Morgan; Sikström, Fredrik; Christiansson, Anna-Karin; Ancona, Antonio

    2017-11-01

    The automated laser beam butt welding process is sensitive to positioning the laser beam with respect to the joint because a small offset may result in detrimental lack of sidewall fusion. This problem is even more pronounced in case of narrow gap butt welding, where most of the commercial automatic joint tracing systems fail to detect the exact position and size of the gap. In this work, a dual vision and spectroscopic sensing approach is proposed to trace narrow gap butt joints during laser welding. The system consists of a camera with suitable illumination and matched optical filters and a fast miniature spectrometer. An image processing algorithm of the camera recordings has been developed in order to estimate the laser spot position relative to the joint position. The spectral emissions from the laser induced plasma plume have been acquired by the spectrometer, and based on the measurements of the intensities of selected lines of the spectrum, the electron temperature signal has been calculated and correlated to variations of process conditions. The individual performances of these two systems have been experimentally investigated and evaluated offline by data from several welding experiments, where artificial abrupt as well as gradual deviations of the laser beam out of the joint were produced. Results indicate that a combination of the information provided by the vision and spectroscopic systems is beneficial for development of a hybrid sensing system for joint tracing.

  10. Nature of the narrow optical band in H*-aggregates: Dozy-chaos–exciton coupling

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Egorov, Vladimir V., E-mail: egorov@photonics.ru

    2014-07-15

    Dozy chaos emerges as a combined effect of the collective chaotic motion of electrons and nuclei, and their chaotic electromagnetic interactions in the transient state of molecules experiencing quantum transitions. Following earlier discussions of the well-known Brönsted relations for proton-transfer reactions; the temperature-dependent electron transfer in Langmuir–Blodgett films; the shape of the optical bands of polymethine dye monomers, their dimers, and J-aggregates, this paper reports one more application of the dozy-chaos theory of molecular quantum transitions. The qualitative and quantitative explanations for shape of a narrow and blue-shifted optical absorption band in H{sup *}-aggregates is given on the basis ofmore » the dozy-chaos theory by taking into account the dozy-chaos–exciton coupling effect. It is emphasized that in the H{sup *}-aggregate chromophore (dimer of cyclic bis-thiacarbocyanines) there is a competition between two Frenkel exciton transitions through the chaotic reorganization motion of nuclear environment. As a result, the highly organized quantum transition to the upper exciton state becomes an exciton-induced source of dozy chaos for the low organized transition to the lower exciton state. This manifests itself in appearing the narrow peak and broad wing in the optical spectrum pattern of H{sup *}-aggregates. A similar enhancement in the H{sup *}-effect caused by the strengthening of the exciton coupling in H{sup *}-dimers, which could be achieved by synthesizing tertiary and quarternary thiacarbocyanine monomers, is predicted.« less

  11. The effect of Cd substitution doping on the bandgap and absorption spectrum of ZnO

    NASA Astrophysics Data System (ADS)

    Hou, Qingyu; Li, Yong; Qu, Lingfeng; Zhao, Chunwang

    2016-08-01

    Many research papers have reported that in the ultraviolet area of 290-360 nm wavelength range, blueshift and redshift in the absorption spectrum occurred in ZnO with Cd doping; however, there is no reasonable theoretical explanation to this so far. To solve this problem, this study investigates the differences of blueshift and redshift in doping system by adopting plane-wave ultrasoft pseudopotential technology based on the density functional theory and applying LDA + U method to calculate band structures, density of states and absorption spectrum distribution of the models, which is on the basis of model geometry optimization. By increasing the Cd doping concentration, the following results are obtained: increased volume of the mixed system, raised total energy, a decrease in stability, narrowed bandgaps and a significant redshift in the absorption spectrum in the ultraviolet or visible light area.

  12. Evidence for a narrow near-threshold structure in the J/psivarphi mass spectrum in B;{+} --> J/psivarphiK;{+} decays.

    PubMed

    Aaltonen, T; Adelman, J; Akimoto, T; Alvarez González, B; Amerio, S; Amidei, D; Anastassov, A; Annovi, A; Antos, J; Apollinari, G; Apresyan, A; Arisawa, T; Artikov, A; Ashmanskas, W; Attal, A; Aurisano, A; Azfar, F; Badgett, W; Barbaro-Galtieri, A; Barnes, V E; Barnett, B A; Barria, P; Bartsch, V; Bauer, G; Beauchemin, P-H; Bedeschi, F; Beecher, D; Behari, S; Bellettini, G; Bellinger, J; Benjamin, D; Beretvas, A; Beringer, J; Bhatti, A; Binkley, M; Bisello, D; Bizjak, I; Blair, R E; Blocker, C; Blumenfeld, B; Bocci, A; Bodek, A; Boisvert, V; Bolla, G; Bortoletto, D; Boudreau, J; Boveia, A; Brau, B; Bridgeman, A; Brigliadori, L; Bromberg, C; Brubaker, E; Budagov, J; Budd, H S; Budd, S; Burke, S; Burkett, K; Busetto, G; Bussey, P; Buzatu, A; Byrum, K L; Cabrera, S; Calancha, C; Campanelli, M; Campbell, M; Canelli, F; Canepa, A; Carls, B; Carlsmith, D; Carosi, R; Carrillo, S; Carron, S; Casal, B; Casarsa, M; Castro, A; Catastini, P; Cauz, D; Cavaliere, V; Cavalli-Sforza, M; Cerri, A; Cerrito, L; Chang, S H; Chen, Y C; Chertok, M; Chiarelli, G; Chlachidze, G; Chlebana, F; Cho, K; Chokheli, D; Chou, J P; Choudalakis, G; Chuang, S H; Chung, K; Chung, W H; Chung, Y S; Chwalek, T; Ciobanu, C I; Ciocci, M A; Clark, A; Clark, D; Compostella, G; Convery, M E; Conway, J; Cordelli, M; Cortiana, G; Cox, C A; Cox, D J; Crescioli, F; Cuenca Almenar, C; Cuevas, J; Culbertson, R; Cully, J C; Dagenhart, D; Datta, M; Davies, T; de Barbaro, P; De Cecco, S; Deisher, A; De Lorenzo, G; Dell'orso, M; Deluca, C; Demortier, L; Deng, J; Deninno, M; Derwent, P F; Di Canto, A; di Giovanni, G P; Dionisi, C; Di Ruzza, B; Dittmann, J R; D'Onofrio, M; Donati, S; Dong, P; Donini, J; Dorigo, T; Dube, S; Efron, J; Elagin, A; Erbacher, R; Errede, D; Errede, S; Eusebi, R; Fang, H C; Farrington, S; Fedorko, W T; Feild, R G; Feindt, M; Fernandez, J P; Ferrazza, C; Field, R; Flanagan, G; Forrest, R; Frank, M J; Franklin, M; Freeman, J C; Furic, I; Gallinaro, M; Galyardt, J; Garberson, F; Garcia, J E; Garfinkel, A F; Garosi, P; Genser, K; Gerberich, H; Gerdes, D; Gessler, A; Giagu, S; Giakoumopoulou, V; Giannetti, P; Gibson, K; Gimmell, J L; Ginsburg, C M; Giokaris, N; Giordani, M; Giromini, P; Giunta, M; Giurgiu, G; Glagolev, V; Glenzinski, D; Gold, M; Goldschmidt, N; Golossanov, A; Gomez, G; Gomez-Ceballos, G; Goncharov, M; González, O; Gorelov, I; Goshaw, A T; Goulianos, K; Gresele, A; Grinstein, S; Grosso-Pilcher, C; Grundler, U; Guimaraes da Costa, J; Gunay-Unalan, Z; Haber, C; Hahn, K; Hahn, S R; Halkiadakis, E; Han, B-Y; Han, J Y; Happacher, F; Hara, K; Hare, D; Hare, M; Harper, S; Harr, R F; Harris, R M; Hartz, M; Hatakeyama, K; Hays, C; Heck, M; Heijboer, A; Heinrich, J; Henderson, C; Herndon, M; Heuser, J; Hewamanage, S; Hidas, D; Hill, C S; Hirschbuehl, D; Hocker, A; Hou, S; Houlden, M; Hsu, S-C; Huffman, B T; Hughes, R E; Husemann, U; Hussein, M; Huston, J; Incandela, J; Introzzi, G; Iori, M; Ivanov, A; James, E; Jang, D; Jayatilaka, B; Jeon, E J; Jha, M K; Jindariani, S; Johnson, W; Jones, M; Joo, K K; Jun, S Y; Jung, J E; Junk, T R; Kamon, T; Kar, D; Karchin, P E; Kato, Y; Kephart, R; Ketchum, W; Keung, J; Khotilovich, V; Kilminster, B; Kim, D H; Kim, H S; Kim, H W; Kim, J E; Kim, M J; Kim, S B; Kim, S H; Kim, Y K; Kimura, N; Kirsch, L; Klimenko, S; Knuteson, B; Ko, B R; Kondo, K; Kong, D J; Konigsberg, J; Korytov, A; Kotwal, A V; Kreps, M; Kroll, J; Krop, D; Krumnack, N; Kruse, M; Krutelyov, V; Kubo, T; Kuhr, T; Kulkarni, N P; Kurata, M; Kwang, S; Laasanen, A T; Lami, S; Lammel, S; Lancaster, M; Lander, R L; Lannon, K; Lath, A; Latino, G; Lazzizzera, I; Lecompte, T; Lee, E; Lee, H S; Lee, S W; Leone, S; Lewis, J D; Lin, C-S; Linacre, J; Lindgren, M; Lipeles, E; Lister, A; Litvintsev, D O; Liu, C; Liu, T; Lockyer, N S; Loginov, A; Loreti, M; Lovas, L; Lucchesi, D; Luci, C; Lueck, J; Lujan, P; Lukens, P; Lungu, G; Lyons, L; Lys, J; Lysak, R; Macqueen, D; Madrak, R; Maeshima, K; Makhoul, K; Maki, T; Maksimovic, P; Malde, S; Malik, S; Manca, G; Manousakis-Katsikakis, A; Margaroli, F; Marino, C; Marino, C P; Martin, A; Martin, V; Martínez, M; Martínez-Ballarín, R; Maruyama, T; Mastrandrea, P; Masubuchi, T; Mathis, M; Mattson, M E; Mazzanti, P; McFarland, K S; McIntyre, P; McNulty, R; Mehta, A; Mehtala, P; Menzione, A; Merkel, P; Mesropian, C; Miao, T; Miladinovic, N; Miller, R; Mills, C; Milnik, M; Mitra, A; Mitselmakher, G; Miyake, H; Moggi, N; Moon, C S; Moore, R; Morello, M J; Morlock, J; Movilla Fernandez, P; Mülmenstädt, J; Mukherjee, A; Muller, Th; Mumford, R; Murat, P; Mussini, M; Nachtman, J; Nagai, Y; Nagano, A; Naganoma, J; Nakamura, K; Nakano, I; Napier, A; Necula, V; Nett, J; Neu, C; Neubauer, M S; Neubauer, S; Nielsen, J; Nodulman, L; Norman, M; Norniella, O; Nurse, E; Oakes, L; Oh, S H; Oh, Y D; Oksuzian, I; Okusawa, T; Orava, R; Osterberg, K; Pagan Griso, S; Palencia, E; Papadimitriou, V; Papaikonomou, A; Paramonov, A A; Parks, B; Pashapour, S; Patrick, J; Pauletta, G; Paulini, M; Paus, C; Peiffer, T; Pellett, D E; Penzo, A; Phillips, T J; Piacentino, G; Pianori, E; Pinera, L; Pitts, K; Plager, C; Pondrom, L; Poukhov, O; Pounder, N; Prakoshyn, F; Pronko, A; Proudfoot, J; Ptohos, F; Pueschel, E; Punzi, G; Pursley, J; Rademacker, J; Rahaman, A; Ramakrishnan, V; Ranjan, N; Redondo, I; Renton, P; Renz, M; Rescigno, M; Richter, S; Rimondi, F; Ristori, L; Robson, A; Rodrigo, T; Rodriguez, T; Rogers, E; Rolli, S; Roser, R; Rossi, M; Rossin, R; Roy, P; Ruiz, A; Russ, J; Rusu, V; Rutherford, B; Saarikko, H; Safonov, A; Sakumoto, W K; Saltó, O; Santi, L; Sarkar, S; Sartori, L; Sato, K; Savoy-Navarro, A; Schlabach, P; Schmidt, A; Schmidt, E E; Schmidt, M A; Schmidt, M P; Schmitt, M; Schwarz, T; Scodellaro, L; Scribano, A; Scuri, F; Sedov, A; Seidel, S; Seiya, Y; Semenov, A; Sexton-Kennedy, L; Sforza, F; Sfyrla, A; Shalhout, S Z; Shears, T; Shepard, P F; Shimojima, M; Shiraishi, S; Shochet, M; Shon, Y; Shreyber, I; Sinervo, P; Sisakyan, A; Slaughter, A J; Slaunwhite, J; Sliwa, K; Smith, J R; Snider, F D; Snihur, R; Soha, A; Somalwar, S; Sorin, V; Spreitzer, T; Squillacioti, P; Stanitzki, M; St Denis, R; Stelzer, B; Stelzer-Chilton, O; Stentz, D; Strologas, J; Strycker, G L; Suh, J S; Sukhanov, A; Suslov, I; Suzuki, T; Taffard, A; Takashima, R; Takeuchi, Y; Tanaka, R; Tecchio, M; Teng, P K; Terashi, K; Thom, J; Thompson, A S; Thompson, G A; Thomson, E; Tipton, P; Ttito-Guzmán, P; Tkaczyk, S; Toback, D; Tokar, S; Tollefson, K; Tomura, T; Tonelli, D; Torre, S; Torretta, D; Totaro, P; Tourneur, S; Trovato, M; Tsai, S-Y; Tu, Y; Turini, N; Ukegawa, F; Vallecorsa, S; van Remortel, N; Varganov, A; Vataga, E; Vázquez, F; Velev, G; Vellidis, C; Vidal, M; Vidal, R; Vila, I; Vilar, R; Vine, T; Vogel, M; Volobouev, I; Volpi, G; Wagner, P; Wagner, R G; Wagner, R L; Wagner, W; Wagner-Kuhr, J; Wakisaka, T; Wallny, R; Wang, S M; Warburton, A; Waters, D; Weinberger, M; Weinelt, J; Wester, W C; Whitehouse, B; Whiteson, D; Wicklund, A B; Wicklund, E; Wilbur, S; Williams, G; Williams, H H; Wilson, P; Winer, B L; Wittich, P; Wolbers, S; Wolfe, C; Wright, T; Wu, X; Würthwein, F; Xie, S; Yagil, A; Yamamoto, K; Yamaoka, J; Yang, U K; Yang, Y C; Yao, W M; Yeh, G P; Yi, K; Yoh, J; Yorita, K; Yoshida, T; Yu, G B; Yu, I; Yu, S S; Yun, J C; Zanello, L; Zanetti, A; Zhang, X; Zheng, Y; Zucchelli, S

    2009-06-19

    Evidence is reported for a narrow structure near the J/psivarphi threshold in exclusive B;{+} --> J/psivarphiK;{+} decays produced in p[over]p collisions at sqrt[s] = 1.96 TeV. A signal of 14 +/- 5 events, with statistical significance in excess of 3.8 standard deviations, is observed in a data sample corresponding to an integrated luminosity of 2.7 fb;{-1}, collected by the CDF II detector. The mass and natural width of the structure are measured to be 4143.0 +/- 2.9(stat) +/- 1.2(syst) MeV/c;{2} and 11.7_{-5.0};{+8.3}(stat) +/- 3.7(syst) MeV/c;{2}.

  13. Design, Construction, Demonstration and Delivery of an Automated Narrow Gap Welding System.

    DTIC Science & Technology

    1982-06-29

    DESIGN, CONSTRUCTION, DEMONSTRATION AND DELIVERY OF WE DA4I &NARROW GAP CONTRACT NO. NOOGOO-81-C-E923 TO DAVID TAYLOR NAVAL RESEARCH AND DEVELOPMENT...the automated * Narrow Gap welding process, is the narrow (3/8 - inch), square-butt joint *design. This narrow joint greatly reduces the volume of weld...AD-i45 495 DESIGN CONSTRUCTION DEMONSTRATION AiND DELIVERY OF RN 1/j AUrOMATED NARROW GAP WELDING SYSTEMI() CRC AUTOMATIC WELDING CO HOUSTON TX 29

  14. Bayesian Face Recognition and Perceptual Narrowing in Face-Space

    PubMed Central

    Balas, Benjamin

    2012-01-01

    During the first year of life, infants’ face recognition abilities are subject to “perceptual narrowing,” the end result of which is that observers lose the ability to distinguish previously discriminable faces (e.g. other-race faces) from one another. Perceptual narrowing has been reported for faces of different species and different races, in developing humans and primates. Though the phenomenon is highly robust and replicable, there have been few efforts to model the emergence of perceptual narrowing as a function of the accumulation of experience with faces during infancy. The goal of the current study is to examine how perceptual narrowing might manifest as statistical estimation in “face space,” a geometric framework for describing face recognition that has been successfully applied to adult face perception. Here, I use a computer vision algorithm for Bayesian face recognition to study how the acquisition of experience in face space and the presence of race categories affect performance for own and other-race faces. Perceptual narrowing follows from the establishment of distinct race categories, suggesting that the acquisition of category boundaries for race is a key computational mechanism in developing face expertise. PMID:22709406

  15. Narrow Escape of Interacting Diffusing Particles

    NASA Astrophysics Data System (ADS)

    Agranov, Tal; Meerson, Baruch

    2018-03-01

    The narrow escape problem deals with the calculation of the mean escape time (MET) of a Brownian particle from a bounded domain through a small hole on the domain's boundary. Here we develop a formalism which allows us to evaluate the nonescape probability of a gas of diffusing particles that may interact with each other. In some cases the nonescape probability allows us to evaluate the MET of the first particle. The formalism is based on the fluctuating hydrodynamics and the recently developed macroscopic fluctuation theory. We also uncover an unexpected connection between the narrow escape of interacting particles and thermal runaway in chemical reactors.

  16. Physical conditions in broad and associated narrow absorption-line systems toward APM 08279+5255

    NASA Astrophysics Data System (ADS)

    Srianand, R.; Petitjean, P.

    2000-05-01

    Results of a careful analysis of the absorption systems with z_abs =~ z_em seen toward the bright, z_em ~ 3.91, gravitationally lensed quasar APM 08279+5255 are presented. Two of the narrow-line systems, at z_abs = 3.8931 and z_abs = 3.9135, show absorptions from singly ionized species with weak or no N v and O vi absorptions at the same redshift. Absorption due to fine structure transitions of C ii and S ii i (excitation energies corresponding to, respectively, 156mu m and 34mu m) are detected at z_abs = 3.8931. Excitation by IR radiation is favored as the column density ratios are consistent with the shape of APM 08279+5255 IR spectrum. The low-ionization state of the system favors a picture where the cloud is closer to the IR source than to the UV source, supporting the idea that the extension of the IR source is larger than ~ 200 pc. The absence of fine structure lines at z_abs = 3.9135 suggests that the gas responsible for this system is farther away from the IR source. Abundances are ~ 0.01 and 1 Zsun at z_abs = 3.913 and 3.8931 and aluminum could be over-abundant with respect to silicon and carbon by at least a factor of two and five. All this suggests that whereas the z_abs = 3.8931 system is probably located within 200 pc from the QSO and ejected at a velocity larger than 1000 km s-1, the z_abs = 3.9135 system is farther away and part of the host-galaxy. Several narrow-line systems have strong absorption lines due to C iv, O vi and N v and very low neutral hydrogen optical depths. This probably implies metallicities Z>= Z_sun although firm conclusion cannot be drawn as the exact value depends strongly on the shape of the ionizing spectrum. The C iv broad absorption has a complex structure with mini-BALs (width <= 1000 km s-1) and narrow components superposed on a continuous absorption of smaller optical depth. The continuous absorption is much stronger in O vi indicating that the corresponding gas-component is of higher ionization than the other components

  17. Parametric Dynamic Load Prediction of a Narrow Gauge Rocket Sled

    DTIC Science & Technology

    2006-12-01

    Monorail λ Compared to Sled Tests.......................................................... 11 Figure 2.1 Application of Vertical λ to a Narrow Gauge sled...Three distinct sled configurations are used: monorail , dual rail wide gauge, and dual rail narrow gauge. Of the three, the narrow gauge...weight and the resulting value was termed λ. Monorail λ factor loading was first documented by Mixon (1971) where a few measured data points were

  18. Background correction in forensic photography. II. Photography of blood under conditions of non-uniform illumination or variable substrate color--practical aspects and limitations.

    PubMed

    Wagner, John H; Miskelly, Gordon M

    2003-05-01

    The combination of photographs taken at wavelengths at and bracketing the peak of a narrow absorbance band can lead to enhanced visualization of the substance causing the narrow absorbance band. This concept can be used to detect putative bloodstains by division of a linear photographic image taken at or near 415 nm with an image obtained by averaging linear photographs taken at or near 395 and 435 nm. Nonlinear images can also be background corrected by substituting subtraction for the division. This paper details experimental applications and limitations of this technique, including wavelength selection of the illuminant and at the camera. Characterization of a digital camera to be used in such a study is also detailed. Detection limits for blood using the three wavelength correction method under optimum conditions have been determined to be as low as 1 in 900 dilution, although on strongly patterned substrates blood diluted more than twenty-fold is difficult to detect. Use of only the 435 nm photograph to estimate the background in the 415 nm image lead to a twofold improvement in detection limit on unpatterned substrates compared with the three wavelength method with the particular camera and lighting system used, but it gave poorer background correction on patterned substrates.

  19. The effect of methacholine-induced acute airway narrowing on lung sounds in normal and asthmatic subjects.

    PubMed

    Schreur, H J; Vanderschoot, J; Zwinderman, A H; Dijkman, J H; Sterk, P J

    1995-02-01

    The association between lung sound alterations and airways obstruction has long been recognized in clinical practice, but the precise pathophysiological mechanisms of this relationship have not been determined. Therefore, we examined the changes in lung sounds at well-defined levels of methacholine-induced airway narrowing in eight normal and nine asthmatic subjects with normal baseline lung function. All subjects underwent phonopneumography at baseline condition and at > or = 20% fall in forced expiratory volume in one second (FEV1), and in asthmatic subjects also at > or = 40% fall in FEV1. Lung sounds were recorded at three locations on the chest wall during standardized quiet breathing, and during maximal forced breathing. Airflow-dependent power spectra were computed using fast Fourier transform. For each spectrum, we determined the intensity and frequency content of lung sounds, together with the extent of wheezing. The results were analysed using analysis of variance (ANOVA). During acute airway narrowing, the intensity and frequency content of the recorded sounds, as well as the extent of wheezing, were higher than at baseline in both groups of subjects. At similar levels of obstruction, both the pitch and the change in sound intensity with airflow were higher in asthmatics than in normal subjects. Wheezing, being nondiscriminative between the subject groups at baseline, was more prominent in asthmatics than in normal subjects at 20% fall in FEV1. We conclude that, at given levels of acute airway narrowing, lung sounds differ between asthmatics and normal subjects. This suggests that airflow-standardized phonopneumography is a sensitive method for detecting abnormalities in airway dynamics in asthma.(ABSTRACT TRUNCATED AT 250 WORDS)

  20. Occupation of the cytochrome P450 substrate pocket by diverse compounds at general anesthesia concentrations.

    PubMed

    LaBella, F S; Stein, D; Queen, G

    1998-10-02

    Each of a diverse array of compounds, at concentrations reported to effect general anesthesia, when added to liver microsomes, forms a complex with cytochromes P450 to generate, with reference to a cuvette containing microsomes only, a characteristic absorbance-difference spectrum. This spectrum results from a change in the electron-spin state of the heme iron atom induced upon entry by the anesthetic molecule into the enzyme catalytic pocket. The difference spectrum, representing the anesthetic-P450 complex, is characteristic of substances that are substrates for the enzyme. For the group of compounds as a whole, the magnitudes of the absorbance-difference spectra vary only about twofold, although the anesthetic potencies vary by several orders of magnitude. The dissociation constants (Ks), calculated from absorbance data and representing affinities of the anesthetics for P450, agree closely with the respective EC50 (concentration that effects anesthesia in 50% of individuals) values, and with the respective Ki (concentration that inhibits P450 catalytic activities half-maximally) values reported by us previously. The absorbance complex resulting from the occupation of the catalytic pocket by endogenous substrates, androstenedione and arachidonic acid, is inhibited, competitively, by anesthetics. Occupation of and perturbation of the heme catalytic pocket by anesthetic, as monitored by the absorbance-difference spectrum, is rapidly reversible. The presumed in vivo consequences of perturbation by general anesthetics of heme proteins is suppression of the generation of chemical signals that determine cell sensitivity and response.

  1. Pulse stretcher for narrow pulses

    NASA Technical Reports Server (NTRS)

    Lindsey, R. S., Jr. (Inventor)

    1974-01-01

    A pulse stretcher for narrow pulses is presented. The stretcher is composed of an analog section for processing each arriving analog pulse and a digital section with logic for providing command signals to the gates and switches in the analog section.

  2. SERS substrates fabricated using ceramic filters for the detection of bacteria: Eliminating the citrate interference

    NASA Astrophysics Data System (ADS)

    Mosier-Boss, P. A.; Sorensen, K. C.; George, R. D.; Sims, P. C.; O'braztsova, A.

    2017-06-01

    It was found that spectra obtained for bacteria on SERS substrates fabricated by filtering citrate-generated Ag nanoparticles (NPs) onto rigid, ceramic filters exhibited peaks due to citrate as well as the bacteria. In many cases the citrate spectrum overwhelmed that of the bacteria. Given the simplicity of the method to prepare these substrates, means of eliminating this citrate interference were explored. It was found that allowing a mixture of bacteria suspension and citrate-generated Ag NPs to incubate prior to filtering onto the ceramic filter eliminated this interference.

  3. Narrow linewidth picosecond UV pulsed laser with mega-watt peak power.

    PubMed

    Huang, Chunning; Deibele, Craig; Liu, Yun

    2013-04-08

    We demonstrate a master oscillator power amplifier (MOPA) burst mode laser system that generates 66 ps/402.5 MHz pulses with mega-watt peak power at 355 nm. The seed laser consists of a single frequency fiber laser (linewidth < 5 KHz), a high bandwidth electro-optic modulator (EOM), a picosecond pulse generator, and a fiber based preamplifier. A very high extinction ratio (45 dB) has been achieved by using an adaptive bias control of the EOM. The multi-stage Nd:YAG amplifier system allows a uniformly temporal shaping of the macropulse with a tunable pulse duration. The light output from the amplifier is converted to 355 nm, and over 1 MW peak power is obtained when the laser is operating in a 5-μs/10-Hz macropulse mode. The laser output has a transform-limited spectrum with a very narrow linewidth of individual longitudinal modes. The immediate application of the laser system is the laser-assisted hydrogen ion beam stripping for the Spallation Neutron Source (SNS).

  4. Finding pathways to prepare Fe4N thin films at low substrate temperature

    NASA Astrophysics Data System (ADS)

    Seema, Gupta, Nitiand Mukul

    2018-04-01

    In Fe-N phase diagram the formation of Fe4N thin films occur in a very narrow region, specially below 573 K. Above this, the range of homogeneity for formation of Fe4N start to increase yielding more favorable conditions for formation of single phase Fe4N. However, when deposited at high substrate temperature (Ts) typically above 650 K, nitrogen (N) tends to diffuse out of the system yielding a N deficient phase. In this work, we attempt to find pathways to deposit Fe4N thin films at low Ts and successfully prepared single phase Fe4N thin films at Ts as low as 423 K. This was achieved by utilizing an underlayer of CrN. We find that such underlayer not only has close lattice matching with Fe4N, it also acts as a diffusion barrier for the film-substrate interface.

  5. Transmission of 2.5 Gbit/s Spectrum-sliced WDM System for 50 km Single-mode Fiber

    NASA Astrophysics Data System (ADS)

    Ahmed, Nasim; Aljunid, Sayed Alwee; Ahmad, R. Badlisha; Fadil, Hilal Adnan; Rashid, Mohd Abdur

    2011-06-01

    The transmission of a spectrum-sliced WDM channel at 2.5 Gbit/s for 50 km of single mode fiber using an system channel spacing only 0.4 nm is reported. We have investigated the system performance using NRZ modulation format. The proposed system is compared with conventional system. The system performance is characterized as the bit-error-rate (BER) received against the system bit rates. Simulation results show that the NRZ modulation format performs well for 2.5 Gbit/s system bit rates. Using this narrow channel spectrum-sliced technique, the total number of multiplexed channels can be increased greatly in WDM system. Therefore, 0.4 nm channel spacing spectrum-sliced WDM system is highly recommended for the long distance optical access networks, like the Metro Area Network (MAN), Fiber-to-the-Building (FTTB) and Fiber-to-the-Home (FTTH).

  6. Bilateral substrate effect on the thermal conductivity of two-dimensional silicon

    NASA Astrophysics Data System (ADS)

    Zhang, Xiaoliang; Bao, Hua; Hu, Ming

    2015-03-01

    Silicene, the silicon-based counterpart of graphene, has received exceptional attention from a wide community of scientists and engineers in addition to graphene, due to its unique and fascinating physical and chemical properties. Recently, the thermal transport of the atomic thin Si layer, critical to various applications in nanoelectronics, has been studied; however, to date, the substrate effect has not been investigated. In this paper, we present our nonequilibrium molecular dynamics studies on the phonon transport of silicene supported on different substrates. A counter-intuitive phenomenon, in which the thermal conductivity of silicene can be either enhanced or suppressed by changing the surface crystal plane of the substrate, has been observed. This phenomenon is fundamentally different from the general understanding of supported graphene, a representative two-dimensional material, in which the substrate always has a negative effect on the phonon transport of graphene. By performing phonon polarization and spectral energy density analysis, we explain the underlying physics of the new phenomenon in terms of the different impacts on the dominant phonons in the thermal transport of silicene induced by the substrate: the dramatic increase in the thermal conductivity of silicene supported on the 6H-SiC substrate is due to the augmented lifetime of the majority of the acoustic phonons, while the significant decrease in the thermal conductivity of silicene supported on the 3C-SiC substrate results from the reduction in the lifetime of almost the entire phonon spectrum. Our results suggest that, by choosing different substrates, the thermal conductivity of silicene can be largely tuned, which paves the way for manipulating the thermal transport properties of silicene for future emerging applications.

  7. An expert-based model for selecting the most suitable substrate material type for antenna circuits

    NASA Astrophysics Data System (ADS)

    AL-Oqla, Faris M.; Omar, Amjad A.

    2015-06-01

    Quality and properties of microwave circuits depend on all the circuit components. One of these components is the substrate. The process of substrate material selection is a decision-making problem that involves multicriteria with objectives that are diverse and conflicting. The aim of this work was to select the most suitable substrate material type to be used in antennas in the microwave frequency range that gives best performance and reliability of the substrate. For this purpose, a model was built to ease the decision-making that includes hierarchical alternatives and criteria. The substrate material type options considered were limited to fiberglass-reinforced epoxy laminates (FR4 εr = 4.8), aluminium (III) oxide (alumina εr = 9.6), gallium arsenide III-V compound (GaAs εr = 12.8) and PTFE composites reinforced with glass microfibers (Duroid εr = 2.2-2.3). To assist in building the model and making decisions, the analytical hierarchy process (AHP) was used. The decision-making process revealed that alumina substrate material type was the most suitable choice for the antennas in the microwave frequency range that yields best performance and reliability. In addition, both the size of the circuit and the loss tangent of the substrates were found to be the most contributing subfactors in the antenna circuit specifications criterion. Experimental assessments were conducted utilising The Expert Choice™ software. The judgments were tested and found to be precise, consistent and justifiable, and the marginal inconsistency values were found to be very narrow. A sensitivity analysis was also presented to demonstrate the confidence in the drawn conclusions.

  8. Leaf Level Chlorophyll Fluorescence Emission Spectra: Narrow Band versus Full 650-800 nm Retrievals

    NASA Astrophysics Data System (ADS)

    Middleton, E.; Zhang, Q.; Campbell, P. K.; Huemmrich, K. F.; Corp, L.; Cheng, Y.

    2012-12-01

    Recently, chlorophyll fluorescence (ChlF) retrievals in narrow spectral regions (< 1 nm, between 750-770 nm) of the near infrared (NIR) region of Earth's reflected radiation have been achieved from satellites, including the Japanese GOSAT and the European Space Agency's Sciamachy/Envisat. However, these retrievals sample the total full-spectrum ChlF and are made at non-optimal wavelengths since they are not located at the peak fluorescence emission features. We wish to estimate the total full-spectrum ChlF based on emissions obtained at selected wavelengths. For this, we drew upon leaf emission spectra measured on corn leaves obtained from a USDA experimental cornfield in MD (USA). These emission spectra were determined for the adaxial and abaxial (i.e., top and underside) surfaces of leaves measured throughout the 2008 and 2011 growing seasons (n>400) using a laboratory instrument (Fluorolog-3, Horiba Scientific, USA), recorded in either 1 nm or 5 nm increments with monochromatic excitation wavelengths of either 532 or 420 nm. The total ChlF signal was computed as the area under the continuous spectral emission curves, summing the emission intensities (counts per second) per waveband. The individual narrow (1 or 5 nm) waveband emission intensities were linearly related to full emission values, with variable success across the spectrum. Equations were developed to estimate total ChlF from these individual wavebands. Here, we report the results for the average adaxial/abaxial emissions. Very strong relationships were achieved for the relatively high fluorescence intensities at the red chlorophyll peak, centered at 685 nm (r2= 0.98, RMSE = 5.53 x 107 photons/s) and in the nearby O2-B atmospheric absorption feature centered at 688 nm (r2 = 0.94, RMSE = 4.04 x 107), as well as in the far-red peak centered at 740 nm (r2=0.94, RMSE = 5.98 x107). Very good retrieval success occurred for the O2-A atmospheric absorption feature on the declining NIR shoulder centered at 760

  9. Broadband Absorbing Exciton-Plasmon Metafluids with Narrow Transparency Windows.

    PubMed

    Yang, Jihua; Kramer, Nicolaas J; Schramke, Katelyn S; Wheeler, Lance M; Besteiro, Lucas V; Hogan, Christopher J; Govorov, Alexander O; Kortshagen, Uwe R

    2016-02-10

    Optical metafluids that consist of colloidal solutions of plasmonic and/or excitonic nanomaterials may play important roles as functional working fluids or as means for producing solid metamaterial coatings. The concept of a metafluid employed here is based on the picture that a single ballistic photon, propagating through the metafluid, interacts with a large collection of specifically designed optically active nanocrystals. We demonstrate water-based metafluids that act as broadband electromagnetic absorbers in a spectral range of 200-3300 nm and feature a tunable narrow (∼100 nm) transparency window in the visible-to-near-infrared region. To define this transparency window, we employ plasmonic gold nanorods. We utilize excitonic boron-doped silicon nanocrystals as opaque optical absorbers ("optical wall") in the UV and blue-green range of the spectrum. Water itself acts as an opaque "wall" in the near-infrared to infrared. We explore the limits of the concept of a "simple" metafluid by computationally testing and validating the effective medium approach based on the Beer-Lambert law. According to our simulations and experiments, particle aggregation and the associated decay of the window effect are one example of the failure of the simple metafluid concept due to strong interparticle interactions.

  10. Xpo7 is a broad-spectrum exportin and a nuclear import receptor.

    PubMed

    Aksu, Metin; Pleiner, Tino; Karaca, Samir; Kappert, Christin; Dehne, Heinz-Jürgen; Seibel, Katharina; Urlaub, Henning; Bohnsack, Markus T; Görlich, Dirk

    2018-05-10

    Exportins bind cargo molecules in a RanGTP-dependent manner inside nuclei and transport them through nuclear pores to the cytoplasm. CRM1/Xpo1 is the best-characterized exportin because specific inhibitors such as leptomycin B allow straightforward cargo validations in vivo. The analysis of other exportins lagged far behind, foremost because no such inhibitors had been available for them. In this study, we explored the cargo spectrum of exportin 7/Xpo7 in depth and identified not only ∼200 potential export cargoes but also, surprisingly, ∼30 nuclear import substrates. Moreover, we developed anti-Xpo7 nanobodies that acutely block Xpo7 function when transfected into cultured cells. The inhibition is pathway specific, mislocalizes export cargoes of Xpo7 to the nucleus and import substrates to the cytoplasm, and allowed validation of numerous tested cargo candidates. This establishes Xpo7 as a broad-spectrum bidirectional transporter and paves the way for a much deeper analysis of exportin and importin function in the future. © 2018 Aksu et al.

  11. The narrow pentaquark

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Diakonov, Dmitri

    2007-02-27

    The experimental status of the pentaquark searches is briefly reviewed. Recent null results by the CLAS collaboration are commented, and new strong evidence of a very narrow {theta}+ resonance by the DIANA collaboration is presented. On the theory side, I revisit the argument against the existence of the pentaquark - that of Callan and Klebanov - and show that actually a strong resonance is predicted in that approach, however its width is grossly overestimated. A recent calculation gives 2 MeV for the pentaquark width, and this number is probably still an upper bound.

  12. Cenesthopathy in adolescence: an appraisal of diagnostic overlaps along the anxiety-hypochondriasis-psychosis spectrum.

    PubMed

    Simon, Andor E; Borgwardt, Stefan; Lang, Undine E; Roth, Binia

    2014-07-01

    To discuss the diagnostic validity of unusual bodily perceptions along the spectrum from age-specific, often transitory and normal, to pathological phenomena in adolescence to hypochondriasis and finally to psychosis. Critical literature review of the cornerstone diagnostic groups along the spectrum embracing anxiety and cenesthopathy in adolescence, hypochondriasis, and cenesthopathy and psychosis, followed by a discussion of the diagnostic overlaps along this spectrum. The review highlights significant overlaps between the diagnostic cornerstones. It is apparent that adolescents with unusual bodily perceptions may conceptually qualify for more than one diagnostic group along the spectrum. To determine whether cenesthopathies in adolescence mirror emerging psychosis, a number of issues need to be considered, i.e. age and mode of onset, gender, level of functioning and drug use. The role of overvalued ideas at the border between hypochondriasis and psychosis must be considered. As unusual bodily symptoms may in some instances meet formal psychosis risk criteria, a narrow understanding of these symptoms may lead to both inappropriate application of the new DSM-5 attenuated psychosis syndrome and of treatment selection. On the other hand, the possibility of a psychotic dimension of unusual bodily symptoms in adolescents must always be considered as most severe expression of the cenesthopathy spectrum. Copyright © 2014 Elsevier Inc. All rights reserved.

  13. Galaxy properties from J-PAS narrow-band photometry

    NASA Astrophysics Data System (ADS)

    Mejía-Narváez, A.; Bruzual, G.; Magris, C. G.; Alcaniz, J. S.; Benítez, N.; Carneiro, S.; Cenarro, A. J.; Cristóbal-Hornillos, D.; Dupke, R.; Ederoclite, A.; Marín-Franch, A.; de Oliveira, C. Mendes; Moles, M.; Sodre, L.; Taylor, K.; Varela, J.; Ramió, H. Vázquez

    2017-11-01

    We study the consistency of the physical properties of galaxies retrieved from spectral energy distribution (SED) fitting as a function of spectral resolution and signal-to-noise ratio (SNR). Using a selection of physically motivated star formation histories, we set up a control sample of mock galaxy spectra representing observations of the local Universe in high-resolution spectroscopy, and in 56 narrow-band and 5 broad-band photometry. We fit the SEDs at these spectral resolutions and compute their corresponding stellar mass, the mass- and luminosity-weighted age and metallicity, and the dust extinction. We study the biases, correlations and degeneracies affecting the retrieved parameters and explore the role of the spectral resolution and the SNR in regulating these degeneracies. We find that narrow-band photometry and spectroscopy yield similar trends in the physical properties derived, the former being considerably more precise. Using a galaxy sample from the Sloan Digital Sky Survey (SDSS), we compare more realistically the results obtained from high-resolution and narrow-band SEDs (synthesized from the same SDSS spectra) following the same spectral fitting procedures. We use results from the literature as a benchmark to our spectroscopic estimates and show that the prior probability distribution functions, commonly adopted in parametric methods, may introduce biases not accounted for in a Bayesian framework. We conclude that narrow-band photometry yields the same trend in the age-metallicity relation in the literature, provided it is affected by the same biases as spectroscopy, albeit the precision achieved with the latter is generally twice as large as with the narrow-band, at SNR values typical of the different kinds of data.

  14. Enhancing Psychosis-Spectrum Nosology Through an International Data Sharing Initiative.

    PubMed

    Docherty, Anna R; Fonseca-Pedrero, Eduardo; Debbané, Martin; Chan, Raymond C K; Linscott, Richard J; Jonas, Katherine G; Cicero, David C; Green, Melissa J; Simms, Leonard J; Mason, Oliver; Watson, David; Ettinger, Ulrich; Waszczuk, Monika; Rapp, Alexander; Grant, Phillip; Kotov, Roman; DeYoung, Colin G; Ruggero, Camilo J; Eaton, Nicolas R; Krueger, Robert F; Patrick, Christopher; Hopwood, Christopher; O'Neill, F Anthony; Zald, David H; Conway, Christopher C; Adkins, Daniel E; Waldman, Irwin D; van Os, Jim; Sullivan, Patrick F; Anderson, John S; Shabalin, Andrey A; Sponheim, Scott R; Taylor, Stephan F; Grazioplene, Rachel G; Bacanu, Silviu A; Bigdeli, Tim B; Haenschel, Corinna; Malaspina, Dolores; Gooding, Diane C; Nicodemus, Kristin; Schultze-Lutter, Frauke; Barrantes-Vidal, Neus; Mohr, Christine; Carpenter, William T; Cohen, Alex S

    2018-05-16

    The latent structure of schizotypy and psychosis-spectrum symptoms remains poorly understood. Furthermore, molecular genetic substrates are poorly defined, largely due to the substantial resources required to collect rich phenotypic data across diverse populations. Sample sizes of phenotypic studies are often insufficient for advanced structural equation modeling approaches. In the last 50 years, efforts in both psychiatry and psychological science have moved toward (1) a dimensional model of psychopathology (eg, the current Hierarchical Taxonomy of Psychopathology [HiTOP] initiative), (2) an integration of methods and measures across traits and units of analysis (eg, the RDoC initiative), and (3) powerful, impactful study designs maximizing sample size to detect subtle genomic variation relating to complex traits (the Psychiatric Genomics Consortium [PGC]). These movements are important to the future study of the psychosis spectrum, and to resolving heterogeneity with respect to instrument and population. The International Consortium of Schizotypy Research is composed of over 40 laboratories in 12 countries, and to date, members have compiled a body of schizotypy- and psychosis-related phenotype data from more than 30000 individuals. It has become apparent that compiling data into a protected, relational database and crowdsourcing analytic and data science expertise will result in significant enhancement of current research on the structure and biological substrates of the psychosis spectrum. The authors present a data-sharing infrastructure similar to that of the PGC, and a resource-sharing infrastructure similar to that of HiTOP. This report details the rationale and benefits of the phenotypic data collective and presents an open invitation for participation.

  15. The Effect of Divided Attention on Emotion-Induced Memory Narrowing

    PubMed Central

    Steinmetz, Katherine R. Mickley; Waring, Jill D.; Kensinger, Elizabeth A.

    2014-01-01

    Individuals are more likely to remember emotional than neutral information, but this benefit does not always extend to the surrounding background information. This memory narrowing is theorized to be linked to the availability of attentional resources at encoding. In contrast to the predictions of this theoretical account, altering participants’ attentional resources at encoding, by dividing attention, did not affect the emotion-induced memory narrowing. Attention was divided using three separate manipulations: a digit ordering task (Experiment 1), an arithmetic task (Experiment 2), and an auditory discrimination task (Experiment 3). Across all three experiments, divided attention decreased memory across-the-board but did not affect the degree of memory narrowing. These findings suggest that theories to explain memory narrowing must be expanded to include other potential mechanisms beyond limitations of attentional resources. PMID:24295041

  16. The effect of divided attention on emotion-induced memory narrowing.

    PubMed

    Mickley Steinmetz, Katherine R; Waring, Jill D; Kensinger, Elizabeth A

    2014-01-01

    Individuals are more likely to remember emotional than neutral information, but this benefit does not always extend to the surrounding background information. This memory narrowing is theorised to be linked to the availability of attentional resources at encoding. In contrast to the predictions of this theoretical account, altering participants' attentional resources at encoding by dividing attention did not affect emotion-induced memory narrowing. Attention was divided using three separate manipulations: a digit ordering task (Experiment 1), an arithmetic task (Experiment 2) and an auditory discrimination task (Experiment 3). Across all three experiments, divided attention decreased memory across the board but did not affect the degree of memory narrowing. These findings suggest that theories to explain memory narrowing must be expanded to include other potential mechanisms beyond the limitations of attentional resources.

  17. Bayesian Face Recognition and Perceptual Narrowing in Face-Space

    ERIC Educational Resources Information Center

    Balas, Benjamin

    2012-01-01

    During the first year of life, infants' face recognition abilities are subject to "perceptual narrowing", the end result of which is that observers lose the ability to distinguish previously discriminable faces (e.g. other-race faces) from one another. Perceptual narrowing has been reported for faces of different species and different races, in…

  18. 1030 nm high power polarization maintained fiber laser with narrow linewidth and near-diffraction-limited beam quality

    NASA Astrophysics Data System (ADS)

    Chu, Qiuhui; Zhao, Pengfei; Li, Chengyu; Wang, Bopeng; Lin, Honghuan; Guo, Chao; Liu, Yu; Jing, Feng; Tang, Chuanxiang

    2018-03-01

    A high power 1030 nm ytterbium-doped polarization maintained fiber laser with optimized parameters is presented in this paper. The master oscillator power amplifier system with counter-pumped amplifier is established. The output power is 900 W, along with a light-to-light efficiency of 64.2%. The amplified spontaneous emission suppression ratio of spectrum reaches to 40 dB with 3 dB linewidth of 0.14 nm. The polarization extinction ratio is 12 dB, and the beam quality factor is M2x=1.07, M2y=1.12. To the best of our knowledge, this is the first demonstration of 1030 nm high power fiber laser with narrow linewidth, near linear polarization, and neardiffraction-limited beam quality

  19. Very narrow excited Ωc baryons

    NASA Astrophysics Data System (ADS)

    Karliner, Marek; Rosner, Jonathan L.

    2017-06-01

    Recently, LHCb reported the discovery of five extremely narrow excited Ωc baryons decaying into Ξc+K-. We interpret these baryons as bound states of a c quark and a P -wave s s diquark. For such a system, there are exactly five possible combinations of spin and orbital angular momentum. The narrowness of the states could be a signal that it is hard to pull apart the two s quarks in a diquark. We predict two of spin 1 /2 , two of spin 3 /2 , and one of spin 5 /2 , all with negative parity. Of the five states, two can decay in S -wave, and three can decay in D -wave. Some of the D -wave states might be narrower than the S -wave states. We discuss the relations among the five masses expected in the quark model and the likely spin assignments, and we compare them with the data. A similar pattern is expected for negative-parity excited Ωb states. An alternative interpretation is noted in which the heaviest two states are 2 S excitations with JP=1 /2+ and 3 /2+, while the lightest three are those with JP=3 /2- , 3 /2- , 5 /2- , expected to decay via D -waves. In this case, we expect JP=1 /2- Ωc states around 2904 and 2978 MeV.

  20. An XMM-Newton Study of the Bright Ultrasoft Narrow-Line Quasar NAB 0205+024

    NASA Technical Reports Server (NTRS)

    Brandt, Niel

    2004-01-01

    The broad-band X-ray continuum of NAB 0205424 is well constrained due to the excellent photon statistics obtained (about 97,700 counts), and its impressive soft X-ray excess is clearly apparent. The hard X-ray power law has become notably steeper than when NAB 0205424 was observed with ASCA, attesting to the presence of significant X-ray spectral variability. A strong and broad emission feature is detected from about 5 to 6.4 keV, and we have modeled this as a relativistic line emitted close to the black hole from a narrow annulus of the accretion disk. Furthermore, a strong X-ray flare is detected with a hard X-ray spectrum; this flare may be responsible for illuminating the inner line-emitting part of the accretion disk. The combined observational results can be broadly interpreted in terms of the "thundercloud model proposed by Merloni & Fabian (2001).

  1. Spectroscopic properties of triangular silver nanoplates immobilized on polyelectrolyte multilayer-modified glass substrates

    NASA Astrophysics Data System (ADS)

    Rabor, Janice B.; Kawamura, Koki; Muko, Daiki; Kurawaki, Junichi; Niidome, Yasuro

    2017-07-01

    Fabrication of surface-immobilized silver nanostructures with reproducible plasmonic properties by dip-coating technique is difficult due to shape alteration. To address this challenge, we used a polyelectrolyte multilayer to promote immobilization of as-received triangular silver nanoplates (TSNP) on a glass substrate through electrostatic interaction. The substrate-immobilized TSNP were characterized by absorption spectrophotometry and scanning electron microscopy. The bandwidth and peak position of localized surface plasmon resonance (LSPR) bands can be tuned by simply varying the concentration of the colloidal solution and immersion time. TSNP immobilized from a higher concentration of colloidal solution with longer immersion time produced broadened LSPR bands in the near-IR region, while a lower concentration with shorter immersion time produced narrower bands in the visible region. The shape of the nanoplates was retained even at long immersion time. Analysis of peak positions and bandwidths also revealed the point at which the main species of the immobilization had been changed from isolates to aggregates.

  2. SERS substrates fabricated using ceramic filters for the detection of bacteria: Eliminating the citrate interference.

    PubMed

    Mosier-Boss, P A; Sorensen, K C; George, R D; Sims, P C; O'braztsova, A

    2017-06-05

    It was found that spectra obtained for bacteria on SERS substrates fabricated by filtering citrate-generated Ag nanoparticles (NPs) onto rigid, ceramic filters exhibited peaks due to citrate as well as the bacteria. In many cases the citrate spectrum overwhelmed that of the bacteria. Given the simplicity of the method to prepare these substrates, means of eliminating this citrate interference were explored. It was found that allowing a mixture of bacteria suspension and citrate-generated Ag NPs to incubate prior to filtering onto the ceramic filter eliminated this interference. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. Designing PolyHEMA Substrates that Mimic the Viscoelastic Response of Soft Tissue

    PubMed Central

    Holt, Brian; Tripathi, Anubhav; Morgan, Jeffrey R.

    2011-01-01

    Matching the mechanical properties of a biomaterial to soft tissue is often overlooked despite the fact that it’s well known that cells respond to and are capable of changing their mechanical environment. In this paper, we used NaCl and alginate beads as porogens to make a series of micro- and macro-porous pHEMA substrates [poly(2-hydroxyethly methacrylate)] and quantified their mechanical behavior under low-magnitude shear loads over physiologically relevant frequencies. Using a stress-controlled rheometer, we performed isothermal (37°C) frequency response experiments between 0.628 and 75.4 rad/s [0.01–12Hz] at 0.1% strain. Both micro- and macro-porous pHEMA substrates were predominately elastic in nature with a narrow range of G′ and G″ values that mimicked the response of human skin. The magnitude of the G′ and G″ values of the macro-porous substrates were designed to closely match human skin. To determine how cell growth might alter their mechanical properties, pHEMA substrates were functionalized and human skin fibroblasts grown on them for fourteen days. As a result of cell growth, the magnitude of G′ and G″ increased at low frequencies while also altering the degree of high frequency dependence, indicating that cellular interactions with the micro-pore infrastructure has a profound effect on the viscoelastic behavior of the substrates. These data could be fit to a mathematical model describing a soft solid. A quantitative understanding of the mechanical behavior of biomaterials in regimes that are physiologically relevant and how these mechanics may change after implantation may aid in the design of new materials. PMID:21496821

  4. Telescope and mirrors development for the monolithic silicon carbide instrument of the osiris narrow angle camera

    NASA Astrophysics Data System (ADS)

    Calvel, Bertrand; Castel, Didier; Standarovski, Eric; Rousset, Gérard; Bougoin, Michel

    2017-11-01

    The international Rosetta mission, now planned by ESA to be launched in January 2003, will provide a unique opportunity to directly study the nucleus of comet 46P/Wirtanen and its activity in 2013. We describe here the design, the development and the performances of the telescope of the Narrow Angle Camera of the OSIRIS experiment et its Silicon Carbide telescope which will give high resolution images of the cometary nucleus in the visible spectrum. The development of the mirrors has been specifically detailed. The SiC parts have been manufactured by BOOSTEC, polished by STIGMA OPTIQUE and ion figured by IOM under the prime contractorship of ASTRIUM. ASTRIUM was also in charge of the alignment. The final optical quality of the aligned telescope is 30 nm rms wavefront error.

  5. Dynamics of reflection high-energy electron diffraction intensity oscillations during molecular beam epitaxial growth of GaAs on (111)B GaAs substrates

    NASA Astrophysics Data System (ADS)

    Yen, M. Y.; Haas, T. W.

    1990-06-01

    We have observed intensity oscillations in reflection high-energy electron diffraction during molecular beam epitaxial growth of GaAs on (111)B GaAs substrates. These oscillations only exist over a narrow range of growth conditions and their behavior is strongly dependent on the migration kinetics of group III and the molecular dissociative reaction of group V elements.

  6. The BUSS spectrum of Beta Lyrae. [Balloon-borne Ultraviolet Stellar Spectrograph

    NASA Technical Reports Server (NTRS)

    Hack, M.; Sahade, J.; De Jager, C.; Kondo, Y.

    1983-01-01

    The spectrum of Beta Lyrae from about 1975 to 3010 A taken with the Balloon-borne ultraviolet Stellar Spectrograph experiment in May 1976 at phase 0.61 P is analyzed. Results show the presence of N II semi-forbidden emission and provide evidence for about the same location, in the outer envelope of the system, of the layers responsible for the resonance Mg II doublet emissions and for the "narrow" H-alpha emission. In addition, three sets of absorption lines, P Cygni profiles of Fe III and broad Beals Type III emissions of Mg II, are found to be present.

  7. Observation of the fluorescence spectrum for a driven cascade model system in atomic beam.

    PubMed

    Tian, Si-Cong; Wang, Chun-Liang; Tong, Cun-Zhu; Wang, Li-Jun; Wang, Hai-Hua; Yang, Xiu-Bin; Kang, Zhi-Hui; Gao, Jin-Yue

    2012-10-08

    We experimentally study the resonance fluorescence from an excited two-level atom when the atomic upper level is coupled by a nonresonant field to a higher-lying state in a rubidium atomic beam. The heights, widths and positions of the fluorescence peaks can be controlled by modifying the detuning of the auxiliary field. We explain the observed spectrum with the transition properties of the dressed states generated by the coupling of the two laser fields. We also attribute the line narrowing to the effects of Spontaneously Generated Coherence between the close-lying levels in the dressed state picture generated by the auxiliary field. And the corresponding spectrum can be viewed as the evidence of Spontaneously Generated Coherence. The experimental results agree well with calculations based on the density-matrix equations.

  8. Contrast-enhanced dual-energy subtraction imaging using electronic spectrum-splitting and multi-prism x-ray lenses

    NASA Astrophysics Data System (ADS)

    Fredenberg, Erik; Cederström, Björn; Lundqvist, Mats; Ribbing, Carolina; Åslund, Magnus; Diekmann, Felix; Nishikawa, Robert; Danielsson, Mats

    2008-03-01

    Dual-energy subtraction imaging (DES) is a method to improve the detectability of contrast agents over a lumpy background. Two images, acquired at x-ray energies above and below an absorption edge of the agent material, are logarithmically subtracted, resulting in suppression of the signal from the tissue background and a relative enhancement of the signal from the agent. Although promising, DES is still not widely used in clinical practice. One reason may be the need for two distinctly separated x-ray spectra that are still close to the absorption edge, realized through dual exposures which may introduce motion unsharpness. In this study, electronic spectrum-splitting with a silicon-strip detector is theoretically and experimentally investigated for a mammography model with iodinated contrast agent. Comparisons are made to absorption imaging and a near-ideal detector using a signal-to-noise ratio that includes both statistical and structural noise. Similar to previous studies, heavy absorption filtration was needed to narrow the spectra at the expense of a large reduction in x-ray flux. Therefore, potential improvements using a chromatic multi-prism x-ray lens (MPL) for filtering were evaluated theoretically. The MPL offers a narrow tunable spectrum, and we show that the image quality can be improved compared to conventional filtering methods.

  9. Interrogating Seyferts with NebulaBayes: Spatially Probing the Narrow-line Region Radiation Fields and Chemical Abundances

    NASA Astrophysics Data System (ADS)

    Thomas, Adam D.; Dopita, Michael A.; Kewley, Lisa J.; Groves, Brent A.; Sutherland, Ralph S.; Hopkins, Andrew M.; Blanc, Guillermo A.

    2018-04-01

    NebulaBayes is a new Bayesian code that implements a general method of comparing observed emission-line fluxes to photoionization model grids. The code enables us to extract robust, spatially resolved measurements of abundances in the extended narrow-line regions (ENLRs) produced by Active Galactic Nuclei (AGN). We observe near-constant ionization parameters but steeply radially declining pressures, which together imply that radiation pressure regulates the ENLR density structure on large scales. Our sample includes four “pure Seyfert” galaxies from the S7 survey that have extensive ENLRs. NGC 2992 shows steep metallicity gradients from the nucleus into the ionization cones. An inverse metallicity gradient is observed in ESO 138-G01, which we attribute to a recent gas inflow or minor merger. A uniformly high metallicity and hard ionizing continuum are inferred across the ENLR of Mrk 573. Our analysis of IC 5063 is likely affected by contamination from shock excitation, which appears to soften the inferred ionizing spectrum. The peak of the ionizing continuum E peak is determined by the nuclear spectrum and the absorbing column between the nucleus and the ionized nebula. We cannot separate variation in this intrinsic E peak from the effects of shock or H II region contamination, but E peak measurements nevertheless give insights into ENLR excitation. We demonstrate the general applicability of NebulaBayes by analyzing a nuclear spectrum from the non-active galaxy NGC 4691 using a H II region grid. The NLR and H II region model grids are provided with NebulaBayes for use by the astronomical community.

  10. A Review of SHV Extended-Spectrum β-Lactamases: Neglected Yet Ubiquitous

    PubMed Central

    Liakopoulos, Apostolos; Mevius, Dik; Ceccarelli, Daniela

    2016-01-01

    β-lactamases are the primary cause of resistance to β-lactams among members of the family Enterobacteriaceae. SHV enzymes have emerged in Enterobacteriaceae causing infections in health care in the last decades of the Twentieth century, and they are now observed in isolates in different epidemiological settings both in human, animal and the environment. Likely originated from a chromosomal penicillinase of Klebsiella pneumoniae, SHV β-lactamases currently encompass a large number of allelic variants including extended-spectrum β-lactamases (ESBL), non-ESBL and several not classified variants. SHV enzymes have evolved from a narrow- to an extended-spectrum of hydrolyzing activity, including monobactams and carbapenems, as a result of amino acid changes that altered the configuration around the active site of the β -lactamases. SHV-ESBLs are usually encoded by self-transmissible plasmids that frequently carry resistance genes to other drug classes and have become widespread throughout the world in several Enterobacteriaceae, emphasizing their clinical significance. PMID:27656166

  11. Tailoring topological states in silicene using different halogen-passivated Si(111) substrates

    NASA Astrophysics Data System (ADS)

    Derakhshan, Vahid; Moghaddam, Ali G.; Ceresoli, Davide

    2018-03-01

    We investigate the band structure and topological phases of silicene embedded on halogenated Si(111) surface using density functional theory calculations. Our results show that the Dirac character of low-energy excitations in silicene is almost preserved in the presence of a silicon substrate passivated by various halogens. Nevertheless, the combined effects of symmetry breaking due to both direct and van der Waals interactions between silicene and the substrate, charge transfer from suspended silicene into the substrate, and, finally, the hybridization which leads to the charge redistribution result in a gap in the spectrum of the embedded silicene. We further take the spin-orbit interaction into account and obtain the resulting modification in the gap. The energy gaps with and without spin-orbit coupling vary significantly when different halogen atoms are used for the passivation of the Si surface, and for the case of iodine, they become on the order of 100 meV. To examine the topological properties, we calculate the projected band structure of silicene from which the Berry curvature and Z2 invariant based on the evolution of Wannier charge centers are obtained. As a key finding, it is shown that silicene on halogenated Si substrates has a topological insulating state which can survive even at room temperature for the substrates with iodine and bromine at the surface. Therefore, these results suggest that we can have a reliable, stable, and robust silicene-based two-dimensional topological insulator using the considered substrates.

  12. Narrow bandgap semiconducting silicides: Intrinsic infrared detectors on a silicon chip

    NASA Technical Reports Server (NTRS)

    Mahan, John E.

    1989-01-01

    Polycrystalline thin films of CrSi2, LaSi2, and ReSi2 were grown on silicon substrates. Normal incidence optical transmittance and reflectance measurements were made as a function of wavelength. It was demonstrated that LaSi2 is a metallic conductor, but that CrSi2 and ReSi2 are, in fact, narrow bandgap semiconductors. For CrSi2, the complex index of refraction was determined by computer analysis of the optical data. From the imaginary part, the optical absorption coefficient was determined as a function of photon energy. It was shown that CrSi2 possesses an indirect forbidden energy gap of slightly less than 0.31 eV, and yet it is a very strong absorber of light above the absorption edge. On the other hand, the ReSi2 films exhibit an absorption edge in the vicinity of 0.2 eV. Measurements of the thermal activation energy of resistivity for ReSi2 indicate a bandgap of 0.18 eV. It is concluded that the semiconducting silicides merit further investigation for development as new silicon-compatible infrared detector materials.

  13. Quartz substrate infrared photonic crystal

    NASA Astrophysics Data System (ADS)

    Ghadiri, Khosrow; Rejeb, Jalel; Vitchev, Vladimir N.

    2003-01-01

    This paper presents the fabrication of a planar photonic crystal (p2c) made of a square array of dielectric rods embedded in air, operating in the infrared spectrum. A quartz substrate is employed instead of the commonly used silicon or column III-V substrate. Our square structure has a normalized cylinder radius-to-pitch ratio of r/a = 0.248 and dielectric material contrast ɛr of 4.5. We choose a Z-cut synthetic quartz for its cut (geometry), and etching properties. Then a particular Z-axis etching process is employed in order to ensure the sharp-edged verticality of the rods and fast etching speed. We also present the computer simulations that allowed the establishment of the photonic band gaps (PBG) of our photonic crystal, as well as the actual measurements. An experimental measurement have been carried out and compared with different simulations. It was found that experimental results are in good agreement with different simulation results. Finally, a frequency selective device for optical communication based on the introduction of impurity sites in the photonic crystal is presented. With our proposed structure Optical System on a Chip (OsoC) with micro-cavity based active devices such as lasers, diodes, modulators, couplers, frequency selective emitters, add-drop filters, detectors, mux/demuxes and polarizers connected by passive waveguide links can be realized.

  14. Bandwidth-narrowed Bragg gratings inscribed in double-cladding fiber by femtosecond laser.

    PubMed

    Shi, Jiawei; Li, Yuhua; Liu, Shuhui; Wang, Haiyan; Liu, Ningliang; Lu, Peixiang

    2011-01-31

    Bragg gratings with the bandwidth(FWHM) narrowed up to 79 pm were inscribed in double-cladding fiber with femtosecond radiation and a phase mask followed by an annealing treatment. With the annealing temperature below a critical value, the bandwidth of Bragg gratings induced by Type I-IR and Type II-IR index change was narrowed without the reduction of reflectivity. The bandwidth narrowing is due to the profile transformation of the refractive index modulation caused by the annealing treatment. This mechanism was verified by comparing bandwidth narrowing processes of FBGs written with different power densities.

  15. 3. Photocopied July 1971 from Photo 741, Jordan Narrows Folder ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Photocopied July 1971 from Photo 741, Jordan Narrows Folder #1, Engineering Department, Utah Power and Light Co., Salt Lake City, Utah. INTERIOR VIEW, JULY 2, 1909. - Salt Lake City Water & Electrical Power Company, Jordan Narrows Hydroelectric Plant, Jordan River, Riverton, Salt Lake County, UT

  16. Structures of Two Coronavirus Main Proteases: Implications for Substrate Binding and Antiviral Drug Design

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Xue, Xiaoyu; Yu, Hongwei; Yang, Haitao

    Coronaviruses (CoVs) can infect humans and multiple species of animals, causing a wide spectrum of diseases. The coronavirus main protease (M{sup pro}), which plays a pivotal role in viral gene expression and replication through the proteolytic processing of replicase polyproteins, is an attractive target for anti-CoV drug design. In this study, the crystal structures of infectious bronchitis virus (IBV) MP{sup pro} and a severe acute respiratory syndrome CoV (SARS-CoV) M{sup pro} mutant (H41A), in complex with an N-terminal autocleavage substrate, were individually determined to elucidate the structural flexibility and substrate binding of M{sup pro}. A monomeric form of IBV M{supmore » pro} was identified for the first time in CoV M{sup pro} structures. A comparison of these two structures to other available M{sup pro} structures provides new insights for the design of substrate-based inhibitors targeting CoV M{sup pro}s. Furthermore, a Michael acceptor inhibitor (named N3) was cocrystallized with IBV M{sup pro} and was found to demonstrate in vitro inactivation of IBV M{sup pro} and potent antiviral activity against IBV in chicken embryos. This provides a feasible animal model for designing wide-spectrum inhibitors against CoV-associated diseases. The structure-based optimization of N3 has yielded two more efficacious lead compounds, N27 and H16, with potent inhibition against SARS-CoV M{sup pro}.« less

  17. Droop-free AlxGa1-xN/AlyGa1-yN quantum-disks-in-nanowires ultraviolet LED emitting at 337 nm on metal/silicon substrates.

    PubMed

    Janjua, Bilal; Sun, Haiding; Zhao, Chao; Anjum, Dalaver H; Priante, Davide; Alhamoud, Abdullah A; Wu, Feng; Li, Xiaohang; Albadri, Abdulrahman M; Alyamani, Ahmed Y; El-Desouki, Munir M; Ng, Tien Khee; Ooi, Boon S

    2017-01-23

    Currently the AlGaN-based ultraviolet (UV) solid-state lighting research suffers from numerous challenges. In particular, low internal quantum efficiency, low extraction efficiency, inefficient doping, large polarization fields, and high dislocation density epitaxy constitute bottlenecks in realizing high power devices. Despite the clear advantage of quantum-confinement nanostructure, it has not been widely utilized in AlGaN-based nanowires. Here we utilize the self-assembled nanowires (NWs) with embedding quantum-disks (Qdisks) to mitigate these issues, and achieve UV emission of 337 nm at 32 A/cm2 (80 mA in 0.5 × 0.5 mm2 device), a turn-on voltage of ~5.5 V and droop-free behavior up to 120 A/cm2 of injection current. The device was grown on a titanium-coated n-type silicon substrate, to improve current injection and heat dissipation. A narrow linewidth of 11.7 nm in the electroluminescence spectrum and a strong wavefunctions overlap factor of 42% confirm strong quantum confinement within uniformly formed AlGaN/AlGaN Qdisks, verified using transmission electron microscopy (TEM). The nitride-based UV nanowires light-emitting diodes (NWs-LEDs) grown on low cost and scalable metal/silicon template substrate, offers a scalable, environment friendly and low cost solution for numerous applications, such as solid-state lighting, spectroscopy, medical science and security.

  18. Power electronics substrate for direct substrate cooling

    DOEpatents

    Le, Khiet [Mission Viejo, CA; Ward, Terence G [Redondo Beach, CA; Mann, Brooks S [Redondo Beach, CA; Yankoski, Edward P [Corona, CA; Smith, Gregory S [Woodland Hills, CA

    2012-05-01

    Systems and apparatus are provided for power electronics substrates adapted for direct substrate cooling. A power electronics substrate comprises a first surface configured to have electrical circuitry disposed thereon, a second surface, and a plurality of physical features on the second surface. The physical features are configured to promote a turbulent boundary layer in a coolant impinged upon the second surface.

  19. Narrow-bandwidth tunable picosecond pulses in the visible produced by noncollinear optical parametric amplification with a chirped blue pump.

    PubMed

    Co, Dick T; Lockard, Jenny V; McCamant, David W; Wasielewski, Michael R

    2010-04-01

    Narrow-bandwidth (approximately 27 cm(-1)) tunable picosecond pulses from 480 nm-780 nm were generated from the output of a 1 kHz femtosecond titanium:sapphire laser system using a type I noncollinear optical parametric amplifier (NOPA) with chirped second-harmonic generation (SHG) pumping. Unlike a femtosecond NOPA, this system utilizes a broadband pump beam, the chirped 400 nm SHG of the Ti:sapphire fundamental, to amplify a monochromatic signal beam (spectrally-filtered output of a type II collinear OPA). Optimum geometric conditions for simultaneous phase- and group-velocity matching were calculated in the visible spectrum. This design is an efficient and simple method for generating tunable visible picosecond pulses that are synchronized to the femtosecond pulses.

  20. Reconditioning of Cassini Narrow-Angle Camera

    NASA Image and Video Library

    2002-07-23

    These five images of single stars, taken at different times with the narrow-angle camera on NASA Cassini spacecraft, show the effects of haze collecting on the camera optics, then successful removal of the haze by warming treatments.

  1. Prosodic Patterns in Interaction of Low-Risk and At-Risk-of-Autism Spectrum Disorders Infants and Their Mothers at 12 and 18 Months

    ERIC Educational Resources Information Center

    Quigley, Jean; McNally, Sinéad; Lawson, Sarah

    2016-01-01

    Research has indicated differences in prosodic expression for infants-at-risk-of-autism spectrum disorders (ASD), and it has been proposed that caregiver speech to these infants may also be moderated prosodically. In typical development, the pitch range of maternal infant-directed speech (IDS) narrows and utterance intensity decreases with infant…

  2. 1. Photocopied July 1971 from Photo 745, Jordan Narrows Folder ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Photocopied July 1971 from Photo 745, Jordan Narrows Folder #1, Engineering Department, Utah Power and Light Co., Salt Lake City, Utah. JORDAN STATION, JULY 2, 1909. GENERAL VIEW. - Salt Lake City Water & Electrical Power Company, Jordan Narrows Hydroelectric Plant, Jordan River, Riverton, Salt Lake County, UT

  3. Templating effect of the substrate on the structure of Cu-phthalocyanine thin film

    NASA Astrophysics Data System (ADS)

    Pierantozzi, Gian Marco; Sbroscia, Marco; Ruocco, Alessandro

    2018-03-01

    An experimental study of electronic properties, structure and morphology of Copper-phthalocyanine films deposited onto Al(100) and Au(110), as a function of thickness up to tens of nanometers, is presented. The monolayers grown on these two model substrates are already known to exhibit very different behavior for what concerns both the degree of interaction with the substrate and the formation of long range order; in this experiment, by means of low energy electron scattering and Electron Energy Loss Spectroscopy (EELS), remarkable differences are revealed also in the successive growth. Exploiting the link between the crystal structure and the lineshape of HOMO-LUMO transition in EELS spectrum, two different structural phases are identified, compatible with α and β phases, respectively in the case of the film grown on aluminum and on gold. Besides, the evolution of the specular reflection elastic peak indicates the formation of islands on the gold substrate and a more homogeneous growth on the aluminum one.

  4. Decreased airway narrowing and smooth muscle contraction in hyperresponsive pigs.

    PubMed

    Turner, Debra J; Noble, Peter B; Lucas, Matthew P; Mitchell, Howard W

    2002-10-01

    Increased smooth muscle contractility or reduced smooth muscle mechanical loads could account for the excessive airway narrowing and hyperresponsiveness seen in asthma. These mechanisms were investigated by using an allergen-induced porcine model of airway hyperresponsiveness. Airway narrowing to electric field stimulation was measured in isolated bronchial segments, over a range of transmural pressures (0-20 cmH(2)O). Contractile responses to ACh were measured in bronchial segments and in isolated tracheal smooth muscle strips isolated from control and test (ovalbumin sensitized and challenged) pigs. Test airways narrowed less than controls (P < 0.0001). Test pigs showed reduced contractility to ACh, both in isolated bronchi (P < 0.01) and smooth muscle strips (P < 0.01). Thus isolated airways from pigs exhibiting airway hyperresponsiveness in vivo are hyporesponsive in vitro. The decreased narrowing in bronchi from hyperresponsive pigs may be related to decreased smooth muscle contractility. These data suggest that mechanisms external to the airway wall may be important to the hyperresponsive nature of sensitized lungs.

  5. The effects of narrow and elevated path walking on aperture crossing.

    PubMed

    Hackney, Amy L; Cinelli, Michael E; Denomme, Luke T; Frank, James S

    2015-06-01

    The study investigated the impact that action capabilities have on identifying possibilities for action, particularly how postural threat influences the passability of apertures. To do this, the ability to maintain balance was challenged by manipulating the level of postural threat while walking. First, participants walked along a 7m path and passed through two vertical obstacles spaced 1.1-1.5×the shoulder width apart during normal walking. Next, postural threat was manipulated by having participants complete the task either walking on a narrow, ground level path or on an elevated/narrow path. Despite a decrease in walking speed as well as an increase in trunk sway in both the narrow and elevated/narrow walking conditions, the passability of apertures was only affected when the consequence of instability was greatest. In the elevated/narrow walking condition, individuals maintained a larger critical point (rotated their shoulders for larger aperture widths) compared to normal walking. However, this effect was not observed for the narrow path walking suggesting that the level of postural threat was not enough to impose similar changes to the critical point. Therefore, it appears that manipulating action capabilities by increasing postural threat does indeed influence aperture crossing behavior, however the consequence associated with instability must be high before both gait characteristics and the critical point are affected. Copyright © 2015 Elsevier B.V. All rights reserved.

  6. Perfect narrow band absorber for sensing applications.

    PubMed

    Luo, Shiwen; Zhao, Jun; Zuo, Duluo; Wang, Xinbing

    2016-05-02

    We design and numerically investigate a perfect narrow band absorber based on a metal-metal-dielectric-metal structure which consists of periodic metallic nanoribbon arrays. The absorber presents an ultra narrow absorption band of 1.11 nm with a nearly perfect absorption of over 99.9% in the infrared region. For oblique incidence, the absorber shows an absorption more than 95% for a wide range of incident angles from 0 to 50°. Structure parameters to the influence of the performance are investigated. The structure shows high sensing performance with a high sensitivity of 1170 nm/RIU and a large figure of merit of 1054. The proposed structure has great potential as a biosensor.

  7. Narrow band quantitative and multivariate electroencephalogram analysis of peri-adolescent period

    PubMed Central

    2012-01-01

    Background The peri-adolescent period is a crucial developmental moment of transition from childhood to emergent adulthood. The present report analyses the differences in Power Spectrum (PS) of the Electroencephalogram (EEG) between late childhood (24 children between 8 and 13 years old) and young adulthood (24 young adults between 18 and 23 years old). Results The narrow band analysis of the Electroencephalogram was computed in the frequency range of 0–20 Hz. The analysis of mean and variance suggested that six frequency ranges presented a different rate of maturation at these ages, namely: low delta, delta-theta, low alpha, high alpha, low beta and high beta. For most of these bands the maturation seems to occur later in anterior sites than posterior sites. Correlational analysis showed a lower pattern of correlation between different frequencies in children than in young adults, suggesting a certain asynchrony in the maturation of different rhythms. The topographical analysis revealed similar topographies of the different rhythms in children and young adults. Principal Component Analysis (PCA) demonstrated the same internal structure for the Electroencephalogram of both age groups. Principal Component Analysis allowed to separate four subcomponents in the alpha range. All these subcomponents peaked at a lower frequency in children than in young adults. Conclusions The present approaches complement and solve some of the incertitudes when the classical brain broad rhythm analysis is applied. Children have a higher absolute power than young adults for frequency ranges between 0-20 Hz, the correlation of Power Spectrum (PS) with age and the variance age comparison showed that there are six ranges of frequencies that can distinguish the level of EEG maturation in children and adults. The establishment of maturational order of different frequencies and its possible maturational interdependence would require a complete series including all the different ages. PMID

  8. Narrow band quantitative and multivariate electroencephalogram analysis of peri-adolescent period.

    PubMed

    Martinez, E I Rodríguez; Barriga-Paulino, C I; Zapata, M I; Chinchilla, C; López-Jiménez, A M; Gómez, C M

    2012-08-24

    The peri-adolescent period is a crucial developmental moment of transition from childhood to emergent adulthood. The present report analyses the differences in Power Spectrum (PS) of the Electroencephalogram (EEG) between late childhood (24 children between 8 and 13 years old) and young adulthood (24 young adults between 18 and 23 years old). The narrow band analysis of the Electroencephalogram was computed in the frequency range of 0-20 Hz. The analysis of mean and variance suggested that six frequency ranges presented a different rate of maturation at these ages, namely: low delta, delta-theta, low alpha, high alpha, low beta and high beta. For most of these bands the maturation seems to occur later in anterior sites than posterior sites. Correlational analysis showed a lower pattern of correlation between different frequencies in children than in young adults, suggesting a certain asynchrony in the maturation of different rhythms. The topographical analysis revealed similar topographies of the different rhythms in children and young adults. Principal Component Analysis (PCA) demonstrated the same internal structure for the Electroencephalogram of both age groups. Principal Component Analysis allowed to separate four subcomponents in the alpha range. All these subcomponents peaked at a lower frequency in children than in young adults. The present approaches complement and solve some of the incertitudes when the classical brain broad rhythm analysis is applied. Children have a higher absolute power than young adults for frequency ranges between 0-20 Hz, the correlation of Power Spectrum (PS) with age and the variance age comparison showed that there are six ranges of frequencies that can distinguish the level of EEG maturation in children and adults. The establishment of maturational order of different frequencies and its possible maturational interdependence would require a complete series including all the different ages.

  9. Substrate vibrations during acoustic signalling in the cicada Okanagana rimosa

    PubMed Central

    Stölting, Heiko; Moore, Thomas E.; Lakes-Harlan, Reinhard

    2002-01-01

    Males of the North American cicada Okanagana rimosa (Homoptera: Cicadidae, Tibicininae) emit loud airborne acoustic signals for intraspecific communication. Specialised vibratory signals could not be detected; however, the airborne signal induced substrate vibrations. Both auditory and vibratory spectra peak in the range from 7–10 kHz. Thus, the vibrations show similar frequency components to the sound spectrum within biologically relevant distances. These vibratory signals could be important as signals involved in mate localization and perhaps even as the context for the evolution of the ear in a group of parasitoid flies. PMID:15455036

  10. Gamma-Ray-emitting Narrow-line Seyfert 1 Galaxies in the Sloan Digital Sky Survey

    NASA Astrophysics Data System (ADS)

    Paliya, Vaidehi S.; Ajello, M.; Rakshit, S.; Mandal, Amit Kumar; Stalin, C. S.; Kaur, A.; Hartmann, D.

    2018-01-01

    The detection of significant γ-ray emission from radio-loud narrow-line Seyfert 1 (NLSy1s) galaxies enables us to study jets in environments different than those in blazars. However, due to the small number of known γ-ray-emitting NLSy1 (γ-NLSy1) galaxies, a comprehensive study could not be performed. Here, we report the first detection of significant γ-ray emission from four active galactic nuclei (AGNs), recently classified as NLSy1 from their Sloan Digital Sky Survey (SDSS) optical spectrum. Three flat-spectrum radio quasars (FSRQs) present in the third Large Area Telescope AGN catalog (3LAC) are also found as γ-NLSy1 galaxies. Comparing the γ-ray properties of these objects with 3LAC blazars reveals their spectral shapes to be similar to FSRQs, however, with low γ-ray luminosity (≲1046–47 erg s‑1). In the Wide-field Infrared Survey Explorer color–color diagram, these objects occupy a region mainly populated by FSRQs. Using the H β emission line parameters, we find that on average γ-NLSy1 have smaller black hole masses than FSRQs at similar redshifts. In the low-resolution SDSS image of one of the γ-NLSy1 source, we find the evidence of an extended structure. We conclude by noting that overall many observational properties of γ-NLSy1 sources are similar to FSRQs, and therefore these objects could be their low black hole mass counterparts, as predicted in the literature.

  11. Electrowetting retroreflectors: Scalable and wide-spectrum modulation between corner cube and scattering reflection

    NASA Astrophysics Data System (ADS)

    Kilaru, M. K.; Cumby, B.; Heikenfeld, J.

    2009-01-01

    Corner cube and spherical retroreflectors are ubiquitous in conspicuity and range-finding applications since they reflect light back to the illumination source with unmatched efficiency. We report here a switchable electrowetting retroreflector platform that provides multiple novel features, including (a) using <0.5 μJ/cm2 electrical energy to switch from a light scattering state, (b) low loss and wide spectrum as limited only by the absorption spectrum of water, (c) use of ultrasimple self-assembly of 103-105 liquid lenslets/in.2 on a polymer/Al corner-cube substrate, and (d) change in retroreflected irradiance of >10:1 over a ±30° field of view.

  12. Time-resolved photoluminescence characterization of GaAs nanowire arrays on native substrate

    NASA Astrophysics Data System (ADS)

    Dagytė, Vilgailė; Barrigón, Enrique; Zhang, Wei; Zeng, Xulu; Heurlin, Magnus; Otnes, Gaute; Anttu, Nicklas; Borgström, Magnus T.

    2017-12-01

    Time-resolved photoluminescence (TRPL) measurements of nanowires (NWs) are often carried out on broken-off NWs in order to avoid the ensemble effects as well as substrate contribution. However, the development of NW-array solar cells could benefit from non-destructive optical characterization to allow faster feedback and further device processing. With this work, we show that different NW array and substrate spectral behaviors with delay time and excitation power can be used to determine which part of the sample dominates the detected spectrum. Here, we evaluate TRPL characterization of dense periodic as-grown GaAs NW arrays on a p-type GaAs substrate, including a sample with uncapped GaAs NWs and several samples passivated with AlGaAs radial shell of varied composition and thickness. We observe a strong spectral overlap of substrate and NW signals and find that the NWs can absorb part of the substrate luminescence signal, thus resulting in a modified substrate signal. The level of absorption depends on the NW-array geometry, making a deconvolution of the NW signal very difficult. By studying TRPL of substrate-only and as-grown NWs at 770 and 400 nm excitation wavelengths, we find a difference in spectral behavior with delay time and excitation power that can be used to assess whether the signal is dominated by the NWs. We find that the NW signal dominates with 400 nm excitation wavelength, where we observe two different types of excitation power dependence for the NWs capped with high and low Al composition shells. Finally, from the excitation power dependence of the peak TRPL signal, we extract an estimate of background carrier concentration in the NWs.

  13. Multiwavelength Monitoring of the Enigmatic Narrow-Line Seyfert 1 PMN J0948 0022 in March-July 2009

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Abdo, A.A.; /Naval Research Lab, Wash., D.C. /Federal City Coll.; Ackermann, M.

    Following the recent discovery of {gamma} rays from the radio-loud narrow-line Seyfert 1 galaxy PMN J0948+0022 (z = 0.5846), we started a multiwavelength campaign from radio to {gamma} rays, which was carried out between the end of 2009 March and the beginning of July. The source displayed activity at all the observed wavelengths: a general decreasing trend from optical to {gamma}-ray frequencies was followed by an increase of radio emission after less than two months from the peak of the {gamma}-ray emission. The largest flux change, about a factor of about 4, occurred in the X-ray band. The smallest wasmore » at ultraviolet and near-infrared frequencies, where the rate of the detected photons dropped by a factor 1.6-1.9. At optical wavelengths, where the sampling rate was the highest, it was possible to observe day scale variability, with flux variations up to a factor of about 3. The behavior of PMN J0948+0022 observed in this campaign and the calculated power carried out by its jet in the form of protons, electrons, radiation, and magnetic field are quite similar to that of blazars, specifically of flat-spectrum radio quasars. These results confirm the idea that radio-loud narrow-line Seyfert 1 galaxies host relativistic jets with power similar to that of average blazars.« less

  14. Growth of indium gallium arsenide thin film on silicon substrate by MOCVD technique

    NASA Astrophysics Data System (ADS)

    Chowdhury, Sisir; Das, Anish; Banerji, Pallab

    2018-05-01

    Indium gallium arsenide (InGaAs) thin film with indium phosphide (InP) buffer has been grown on p-type silicon (100) by Metal Organic Chemical Vapor Deposition (MOCVD) technique. To get a lattice matched substrate an Indium Phosphide buffer thin film is deposited onto Si substrate prior to InGaAs growth. The grown films have been investigated by UV-Vis-NIR reflectance spectroscopy. The band gap energy of the grown InGaAs thin films determined to be 0.82 eV from reflectance spectrum and the films are found to have same thickness for growth between 600 °C and 650 °C. Crystalline quality of the grown films has been studied by grazing incidence X-ray diffractometry (GIXRD).

  15. Influence of the narrow {111} planes on axial and planar ion channeling.

    PubMed

    Motapothula, M; Dang, Z Y; Venkatesan, T; Breese, M B H; Rana, M A; Osman, A

    2012-05-11

    We report channeling patterns where clearly resolved effects of the narrow {111} planes are observed in axial and planar alignments for 2 MeV protons passing through a 55 nm [001] silicon membrane. At certain axes, such as <213> and <314>, the offset in atomic rows forming the narrow {111} planes results in shielding from the large potential at the wide {111} planes, producing a region of shallow, asymmetric potential from which axial channeling patterns have no plane of symmetry. At small tilts from such axes, different behavior is observed from the wide and narrow {111} planes. At planar alignment, distinctive channeling effects due to the narrow planes are observed. As a consequence of the shallow potential well at the narrow planes, incident protons suffer dechanneled trajectories which are excluded from channeling within the wide planes, resulting in an anomalously large scattered beam at {111} alignment.

  16. SDSS J211852.96-073227.5: a new γ-ray flaring narrow-line Seyfert 1 galaxy

    NASA Astrophysics Data System (ADS)

    Yang, Hui; Yuan, Weimin; Yao, Su; Li, Ye; Zhang, Jin; Zhou, Hongyan; Komossa, S.; Liu, He-Yang; Jin, Chichuan

    2018-07-01

    We report on the identification of a new γ-ray-emitting narrow-line Seyfert 1 (NLS1) galaxy, SDSS J211852.96-073227.5 (hereinafter J2118-0732). The galaxy, at a redshift of 0.26, is associated with a radio source of flat/inverted spectrum at high radio frequencies. The analysis of its optical spectrum obtained in the Sloan Digital Sky Survey (SDSS) revealed a small linewidth of the broad component of the Hβ line (full width at half-maximum = 1585 km s-1), making it a radio-loud NLS1 galaxy - an intriguing class of active galactic nuclei with exceptional multiwavelength properties. A new γ-ray source centred at J2118-0732 was sporadically detected during 2009-2013 in form of flares by the Fermi-LAT. Our XMM-Newton observations revealed a flat X-ray spectrum described by a simple power law, and a flux variation by a factor of ˜2.5 in five months. The source also shows intraday variability in the infrared band. Its broad-band spectral energy distribution can be modelled by emission from a simple one-zone leptonic jet model, and the flux drop from infrared to X-rays in five months can be explained by changes of the jet parameters, though the exact values may be subject to relatively large uncertainties. With the NLS1-blazar composite nucleus, the clear detection of the host galaxy, and the synchronous variations in the multiwavelength fluxes, J2118-0732 provides a new perspective on the formation and evolution of relativistic jets under the regime of relatively small black hole masses and high accretion rates.

  17. SDSS J211852.96-073227.5: a new γ-ray flaring narrow-line Seyfert 1 galaxy

    NASA Astrophysics Data System (ADS)

    Yang, Hui; Yuan, Weimin; Yao, Su; Li, Ye; Zhang, Jin; Zhou, Hongyan; Komossa, S.; Liu, He-Yang; Jin, Chichuan

    2018-04-01

    We report on the identification of a new γ-ray-emitting narrow-line Seyfert 1 (NLS1) galaxy, SDSS J211852.96-073227.5 (hereafter J2118-0732). The galaxy, at a redshift of 0.26, is associated with a radio source of flat/inverted spectrum at high radio frequencies. The analysis of its optical spectrum obtained in the Sloan Digital Sky Survey revealed a small linewidth of the broad component of the Hβ line (FWHM = 1585 km s-1), making it a radio-loud NLS1 galaxy - an intriguing class of active galactic nuclei with exceptional multi-wavelength properties. A new γ-ray source centred at J2118-0732 was sporadically detected during 2009-2013 in form of flares by the Fermi-LAT. Our XMM-Newton observations revealed a flat X-ray spectrum described by a simple power law, and a flux variation by a factor of ˜2.5 in 5 months. The source also shows intraday variability in the infrared band. Its broad-band spectral energy distribution can be modelled by emission from a simple one-zone leptonic jet model, and the flux drop from infrared to X-rays in five months can be explained by changes of the jet parameters, though the exact values may be subject to relatively large uncertainties. With the NLS1-blazar composite nucleus, the clear detection of the host galaxy and the synchronous variations in the multi-wavelength fluxes, J2118-0732 provides a new perspective on the formation and evolution of relativistic jets under the regime of relatively small black hole masses and high accretion rates.

  18. Narrowing the Gap in Outcomes: Early Years (0-5 Years)

    ERIC Educational Resources Information Center

    Springate, Ian; Atkinson, Mary; Straw, Suzanne; Lamont, Emily; Grayson, Hilary

    2008-01-01

    This report was commissioned by the Local Government Association (LGA) to inform the Department for Children, Schools and Families (DCSF) and LGA work on "Narrowing the Gap." It focuses on early years' provision and presents findings from a review of the best evidence on narrowing the gap in outcomes across the five Every Child Matters…

  19. Energy spectrum control for modulated proton beams.

    PubMed

    Hsi, Wen C; Moyers, Michael F; Nichiporov, Dmitri; Anferov, Vladimir; Wolanski, Mark; Allgower, Chris E; Farr, Jonathan B; Mascia, Anthony E; Schreuder, Andries N

    2009-06-01

    In proton therapy delivered with range modulated beams, the energy spectrum of protons entering the delivery nozzle can affect the dose uniformity within the target region and the dose gradient around its periphery. For a cyclotron with a fixed extraction energy, a rangeshifter is used to change the energy but this produces increasing energy spreads for decreasing energies. This study investigated the magnitude of the effects of different energy spreads on dose uniformity and distal edge dose gradient and determined the limits for controlling the incident spectrum. A multilayer Faraday cup (MLFC) was calibrated against depth dose curves measured in water for nonmodulated beams with various incident spectra. Depth dose curves were measured in a water phantom and in a multilayer ionization chamber detector for modulated beams using different incident energy spreads. Some nozzle entrance energy spectra can produce unacceptable dose nonuniformities of up to +/-21% over the modulated region. For modulated beams and small beam ranges, the width of the distal penumbra can vary by a factor of 2.5. When the energy spread was controlled within the defined limits, the dose nonuniformity was less than +/-3%. To facilitate understanding of the results, the data were compared to the measured and Monte Carlo calculated data from a variable extraction energy synchrotron which has a narrow spectrum for all energies. Dose uniformity is only maintained within prescription limits when the energy spread is controlled. At low energies, a large spread can be beneficial for extending the energy range at which a single range modulator device can be used. An MLFC can be used as part of a feedback to provide specified energy spreads for different energies.

  20. Spectrally narrowed lasing of a self-injection KrF excimer laser

    NASA Astrophysics Data System (ADS)

    Shimada, Yasuhiro; Wani, Koichi; Miki, Tadaaki; Kawahara, Hidehito; Mimasu, Mutsumi; Ogata, Yoshiro

    1990-08-01

    Spectrally nantwed lasing of a KrF excimer laser has teen ahieved by a self-injection technique using abeam splitter for power extraction aixi intravity etalons for spectral-narrowing. The laser cavity is divithi into an amplifying branch aix! a spectralnarrowing branch. The spectral bandwidth was narrowed to <3pm FWHM with air-sed etalons placed in the spectral-narrowing branch. A laser propagation model was intrOdUced for describing the laser intensity traveling in the laser cavity. The calculated intensityincident onthe intracavityetalons wassmaller thanthat in theconventional Fabry-Perotcavity withplane-parallel mirrors.

  1. Anisotropic ultrafast response of MoS2 on rippled substrates

    NASA Astrophysics Data System (ADS)

    Cinquanta, Eugenio; Camellini, Andrea; Martella, Christian; Mennucci, Carlo; Lamperti, Alessio; Della Valle, Giuseppe; Zavelani Rossi, Margherita; Buatier de Mongeot, Francesco; Molle, Alessandro; Stagira, Salvatore

    TMDs represent one of the most promising option for new devices characterized by high performances for opto- and nanoelectronics applications. Top-down schemes have been fruitfully exploited for the tuning of TMDs physics by stain engineering in exfoliated flakes. We propose an original bottom-up strategy based on the CVD growth of MoS2 on anisotropic substrates and its characterization by means of pump-probe spectroscopy. The ultrafast response of the rippled MoS2 reveals strongly anisotropic. While the transient absorption emerges as independent from the orientation of the pump beam polarization, the angle between the probe beam polarization and the ripples induces remarkable effects. Within an orthogonal geometry, both the overall intensity of the transient spectrum and the el-ph scattering decay time are halved while the photo-bleaching at 450 nm is blueshifted with respect to the parallel orientation case. Our results demonstrate that the coupling of TMDs with anisotropic substrates is a promising way for the integration of TMDs photonics devices.

  2. Transitioning to a narrow path: the impact of fear of falling in older adults.

    PubMed

    Dunlap, Pamela; Perera, Subashan; VanSwearingen, Jessie M; Wert, David; Brach, Jennifer S

    2012-01-01

    Everyday ambulation requires navigation of variable terrain, transitions from wide to narrow pathways, and avoiding obstacles. While the effect of age on the transition to a narrow path has been examined briefly, little is known about the impact of fear of falling on gait during the transition to a narrow path. The purpose was to examine the effect of age and fear of falling on gait during transition to a narrow path. In 31 young, mean age=25.3 years, and 30 older adults, mean age=79.6 years, step length, step time, step width and gait speed were examined during usual and transition to narrow pathway using an instrumented walkway. During the transition to narrow walk condition, fearful older adults compared to young had a wider step width (0.06 m vs 0.04 m) prior to the narrow path and took shorter steps (0.53 m vs 0.72 m; p<0.001). Compared to non-fearful older adults, fearful older adults walked slower and took shorter steps during narrow path walking (gait speed: 1.1m/s vs 0.82 m/s; p=0.01; step length: 0.60 m vs 0.47 m; p=0.03). In young and non-fearful older adults narrow path gait was similar to usual gait. Whereas older adults who were fearful, walked slower (0.82 m/s vs 0.91 m/s; p=0.001) and took shorter steps (0.44 m vs 0.53 m; p=0.004) during narrow path walking compared to usual walking. Changes in gait characteristics with transitioning to a narrow pathway were greater for fear of falling than for age. Copyright © 2011 Elsevier B.V. All rights reserved.

  3. InGaP solar cell on Ge-on-Si virtual substrate for novel solar power conversion

    NASA Astrophysics Data System (ADS)

    Kim, T. W.; Albert, B. R.; Kimerling, L. C.; Michel, J.

    2018-02-01

    InGaP single-junction solar cells are grown on lattice-matched Ge-on-Si virtual substrates using metal-organic chemical vapor deposition. Optoelectronic simulation results indicate that the optimal collection length for InGaP single-junction solar cells with a carrier lifetime range of 2-5 ns is wider than approximately 1 μm. Electron beam-induced current measurements reveal that the threading dislocation density (TDD) of InGaP solar cells fabricated on Ge and Ge-on-Si substrates is in the range of 104-3 × 107 cm-2. We demonstrate that the open circuit voltage (Voc) of InGaP solar cells is not significantly influenced by TDDs less than 2 × 106 cm-2. Fabricated InGaP solar cells grown on a Ge-on-Si virtual substrate and a Ge substrate exhibit Voc in the range of 0.96 to 1.43 V under an equivalent illumination in the range of ˜0.5 Sun. The estimated efficiency of the InGaP solar cell fabricated on the Ge-on-Si virtual substrate (Ge substrate) at room temperature for the limited incident spectrum spanning the photon energy range of 1.9-2.4 eV varies from 16.6% to 34.3%.

  4. Ribbed electrode substrates

    DOEpatents

    Breault, Richard D.; Goller, Glen J.

    1983-01-01

    A ribbed substrate for an electrochemical cell electrode is made from a mixture of carbon fibers and carbonizable resin and has a mean pore size in the ribs which is 60-75% of the mean pore size of the web portions of the substrate which interconnect the ribs. Preferably the mean pore size of the web portion is 25-45 microns; and, if the substrate includes edge seals parallel to the ribs, the edge seals preferably have a mean pore size no greater than about ten microns. Most preferably the substrate has the same ratio of carbon fibers to polymeric carbon in all areas, including the ribs, webs, and edge seals. A substrate according to the present invention will have better overall performance than prior art substrates and minimizes the substrate thickness required for the substrate to perform all its functions well.

  5. The extremely narrow-caliber esophagus is a treatment-resistant subphenotype of eosinophilic esophagitis.

    PubMed

    Eluri, Swathi; Runge, Thomas M; Cotton, Cary C; Burk, Caitlin M; Wolf, W Asher; Woosley, John T; Shaheen, Nicholas J; Dellon, Evan S

    2016-06-01

    Some patients with eosinophilic esophagitis (EoE) have an extremely narrow esophagus, but the characteristics of this group have not been extensively described. We aimed to characterize the narrow-caliber phenotype of EoE, determine associated risk factors, and identify differences in treatment response in this subgroup of patients. This retrospective cohort study from 2001 to 2014 included subjects with a new diagnosis of EoE per consensus guidelines. Demographic, endoscopic, histologic, and treatment response data were extracted from medical records. An extremely narrow-caliber esophagus was defined when a neonatal endoscope was required to traverse the esophagus due to the inability to pass an adult endoscope. Patients with and without an extremely narrow-caliber esophagus were compared. Multivariable logistical regression was performed to assess treatment outcomes. Of 513 patients with EoE, 46 (9%) had an extremely narrow-caliber esophagus. These patients were older (33 vs 22 years; P < .01), had longer symptom duration (11 vs 3 years; P < .01), more dysphagia (98% vs 66%; P < .01), and food impactions (53% vs 31%; P < .01). Dilation was more common with extreme narrowing (69% vs 17%; P < .01). Patients with a narrow-caliber esophagus were more refractory to steroid treatment, with lower symptom (56% vs 85%), endoscopic (52% vs 76%), and histologic (33% vs 63%) responses (P < .01 for all), and these differences persisted after multivariate analysis. The extremely narrow-caliber esophagus is a more treatment-resistant subphenotype of EoE and is characterized by longer symptom duration and the need for multiple dilations. Recognition of an extremely narrow-caliber esophagus at diagnosis of EoE can provide important prognostic information. Copyright © 2016 American Society for Gastrointestinal Endoscopy. Published by Elsevier Inc. All rights reserved.

  6. The Autism-Spectrum Quotient--Italian version: a cross-cultural confirmation of the broader autism phenotype.

    PubMed

    Ruta, Liliana; Mazzone, Domenico; Mazzone, Luigi; Wheelwright, Sally; Baron-Cohen, Simon

    2012-04-01

    The Autism Spectrum Quotient (AQ) has been used to define the 'broader' (BAP), 'medium' (MAP) and 'narrow' autism phenotypes (NAP). We used a new Italian version of the AQ to test if difference on AQ scores and the distribution of BAP, MAP and NAP in autism parents (n = 245) versus control parents (n = 300) were replicated in a Sicilian sample. Parents of children with autism spectrum conditions scored higher than the control parents on total AQ, social skills and communication subscales, and exhibited higher rates of BAP, MAP and NAP. We conclude that the Italian AQ is a cross-culturally reliable measure of these different phenotypes, and can be used to identify a phenotypic gradient of severity of autistic traits in families. To understand the molecular basis of these phenotypes will require its use in genetic association studies.

  7. Numerical Study on Outflows in Seyfert Galaxies I: Narrow Line Region Outflows in NGC 4151

    NASA Astrophysics Data System (ADS)

    Mou, Guobin; Wang, Tinggui; Yang, Chenwei

    2017-07-01

    The origin of narrow line region (NLR) outflows remains unknown. In this paper, we explore the scenario in which these outflows are circumnuclear clouds driven by energetic accretion disk winds. We choose the well-studied nearby Seyfert galaxy NGC 4151 as an example. By performing 3D hydrodynamical simulations, we are able to reproduce the radial distributions of velocity, mass outflow rate, and kinetic luminosity of NLR outflows in the inner 100 pc deduced from spatial resolved spectroscopic observations. The demanded kinetic luminosity of disk winds is about two orders of magnitude higher than that inferred from the NLR outflows, but is close to the ultrafast outflows (UFO) detected in the X-ray spectrum and a few times lower than the bolometric luminosity of the Seyfert. Our simulations imply that the scenario is viable for NGC 4151. The existence of the underlying disk winds can be confirmed by their impacts on higher density ISM, e.g., shock excitation signs, and the pressure in NLR.

  8. Reliability and failure modes of narrow implant systems.

    PubMed

    Hirata, Ronaldo; Bonfante, Estevam A; Anchieta, Rodolfo B; Machado, Lucas S; Freitas, Gileade; Fardin, Vinicius P; Tovar, Nick; Coelho, Paulo G

    2016-09-01

    Narrow implants are indicated in areas of limited bone width or when grafting is nonviable. However, the reduction of implant diameter may compromise their performance. This study evaluated the reliability of several narrow implant systems under fatigue, after restored with single-unit crowns. Narrow implant systems were divided (n = 18 each), as follows: Astra (ASC); BioHorizons (BSC); Straumann Roxolid (SNC), Intra-Lock (IMC), and Intra-Lock one-piece abutment (ILO). Maxillary central incisor crowns were cemented and subjected to step-stress accelerated life testing in water. Use level probability Weibull curves and reliability for a mission of 100,000 cycles at 130- and 180-N loads (90 % two-sided confidence intervals) were calculated. Scanning electron microscopy was used for fractography. Reliability for 100,000 cycles at 130 N was ∼99 % in group ASC, ∼99 % in BSC, ∼96 % in SNC, ∼99 % in IMC, and ∼100 % in ILO. At 180 N, reliability of ∼34 % resulted for the ASC group, ∼91 % for BSC, ∼53 % for SNC, ∼70 % for IMC, and ∼99 % for ILO. Abutment screw fracture was the main failure mode for all groups. Reliability was not different between systems for 100,000 cycles at the 130-N load. A significant decrease was observed at the 180-N load for ASC, SNC, and IMC, whereas it was maintained for BSC and ILO. The investigated narrow implants presented mechanical performance under fatigue that suggests their safe use as single crowns in the anterior region.

  9. Solvent-Controlled Synthesis of Highly Luminescent Carbon Dots with a Wide Color Gamut and Narrowed Emission Peak Widths.

    PubMed

    Ding, Hui; Wei, Ji-Shi; Zhang, Peng; Zhou, Zi-Yuan; Gao, Qing-Yu; Xiong, Huan-Ming

    2018-05-01

    Carbon dots (CDs) have tremendous potential applications in bioimaging, biomedicine, and optoelectronics. By far, it is still difficult to produce photoluminescence (PL) tunable CDs with high quantum yield (QY) across the entire visible spectrum and narrow the emission peak widths of CDs close to those of typical quantum dots. In this work, a series of CDs with tunable emission from 443 to 745 nm, quantum yield within 13-54%, and narrowed full width at half maximum (FWHM) from 108 to 55 nm, are obtained by only adjusting the reaction solvents in a one-pot solvothermal route. The distinct optical features of these CDs are based on their differences in the particle size, and the content of graphitic nitrogen and oxygen-containing functional groups, which can be modulated by controlling the dehydration and carbonization processes during solvothermal reactions. Blue, green, yellow, red, and even pure white light emitting films (Commission Internationale de L'Eclairage (CIE)= 0.33, 0.33, QY = 39%) are prepared by dispersing one or three kinds of CDs into polyvinyl alcohol with appropriate ratios. The near-infrared emissive CDs are excellent fluorescent probes for both in vitro and in vivo bioimaging because of their high QY in water, long-term stability, and low cytotoxicity. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  10. Selectively Plasmon-Enhanced Second-Harmonic Generation from Monolayer Tungsten Diselenide on Flexible Substrates.

    PubMed

    Wang, Zhuo; Dong, Zhaogang; Zhu, Hai; Jin, Lei; Chiu, Ming-Hui; Li, Lain-Jong; Xu, Qing-Hua; Eda, Goki; Maier, Stefan A; Wee, Andrew T S; Qiu, Cheng-Wei; Yang, Joel K W

    2018-02-27

    Monolayer two-dimensional transition-metal dichalcogenides (2D TMDCs) exhibit promising characteristics in miniaturized nonlinear optical frequency converters, due to their inversion asymmetry and large second-order nonlinear susceptibility. However, these materials usually have very short light interaction lengths with the pump laser because they are atomically thin, such that second-harmonic generation (SHG) is generally inefficient. In this paper, we fabricate a judiciously structured 150 nm-thick planar surface consisting of monolayer tungsten diselenide and sub-20 nm-wide gold trenches on flexible substrates, reporting ∼7000-fold SHG enhancement without peak broadening or background in the spectra as compared to WSe 2 on as-grown sapphire substrates. Our proof-of-concept experiment yields effective second-order nonlinear susceptibility of 2.1 × 10 4 pm/V. Three orders of magnitude enhancement is maintained with pump wavelength ranging from 800 to 900 nm, breaking the limitation of narrow pump wavelength range for cavity-enhanced SHG. In addition, SHG amplitude can be dynamically controlled via selective excitation of the lateral gap plasmon by rotating the laser polarization. Such a fully open, flat, and ultrathin profile enables a great variety of functional samples with high SHG from one patterned silicon substrate, favoring scalable production of nonlinear converters. The surface accessibility also enables integration with other optical components for information processing in an ultrathin and flexible form.

  11. Large-scale uniform ZnO tetrapods on catalyst free glass substrate by thermal evaporation method

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Alsultany, Forat H., E-mail: foratusm@gmail.com; Hassan, Z.; Ahmed, Naser M.

    2016-07-15

    Highlights: • Investigate the growth of ZnO-Ts on glass substrate by thermal evaporation method. • Glass substrate without any catalyst or a seed layer. • The morphology was controlled by adjusting the temperature of the material and the substrate. • Glass substrate was placed vertically in the quartz tube. - Abstract: Here, we report for the first time the catalyst-free growth of large-scale uniform shape and size ZnO tetrapods on a glass substrate via thermal evaporation method. Three-dimensional networks of ZnO tetrapods have needle–wire junctions, an average leg length of 2.1–2.6 μm, and a diameter of 35–240 nm. The morphologymore » and structure of ZnO tetrapods were investigated by controlling the preparation temperature of each of the Zn powder and the glass substrate under O{sub 2} and Ar gases. Studies were carried out on ZnO tetrapods using X-ray diffraction, field emission scanning electron microscopy, UV–vis spectrophotometer, and a photoluminescence. The results showed that the sample grow in the hexagonal wurtzite structure with preferentially oriented along (002) direction, good crystallinity and high transmittance. The band gap value is about 3.27 eV. Photoluminescence spectrum exhibits a very sharp peak at 378 nm and a weak broad green emission.« less

  12. Leg coordination during turning on an extremely narrow substrate in a bug, Mesocerus marginatus (Heteroptera, Coreidae).

    PubMed

    Frantsevich, Leonid I; Cruse, Holk

    2005-10-01

    The turning movement of a bug, Mesocerus marginatus, is observed when it walks upside-down below a horizontal beam and, at the end of the beam, performs a sharp turn by 180 degrees . The turn at the end of the beam is accomplished in three to five steps, without strong temporal coordination among legs. During the stance, leg endpoints (tarsi) run through rounded trajectories, rotating to the same side in all legs. During certain phases of the turn, a leg is strongly depressed and the tarsus crosses the midline. Swing movements rotate to the same side as do leg endpoints in stance, in strong contrast to the typical swing movements found in turns or straight walk on a flat surface. Terminal location is found after the search through a trajectory that first moves away from the body and then loops back to find substrate. When a leg during stance has crossed the midline, in the following swing movement the leg may move even stronger on the contralateral side, i.e. is stronger depressed, in contrast to swing movements in normal walking, where the leg is elevated. These results suggest that the animals apply a different control strategy compared to walking and turning on a flat surface.

  13. 76 FR 60733 - Drawbridge Operation Regulations; Narrow Bay, Smith Point, NY

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-30

    ... Operation Regulations; Narrow Bay, Smith Point, NY AGENCY: Coast Guard, DHS. ACTION: Notice of temporary... deviation from the regulation governing the operation of the Smith Point Bridge, 6.1, across Narrow Bay, between Smith Point and Fire Island, New York. The deviation is necessary to facilitate bridge...

  14. Electronic structure descriptor for the discovery of narrow-band red-emitting phosphors

    DOE PAGES

    Wang, Zhenbin; Chu, Iek -Heng; Zhou, Fei; ...

    2016-05-09

    Narrow-band red-emitting phosphors are a critical component of phosphor-converted light-emitting diodes for highly efficient illumination-grade lighting. In this work, we report the discovery of a quantitative descriptor for narrow-band Eu 2+-activated emission identified through a comparison of the electronic structures of known narrow-band and broad-band phosphors. We find that a narrow emission bandwidth is characterized by a large splitting of more than 0.1 eV between the two highest Eu 2+ 4 f 7 bands. By incorporating this descriptor in a high-throughput first-principles screening of 2259 nitride compounds, we identify five promising new nitride hosts for Eu 2+-activated red-emitting phosphors thatmore » are predicted to exhibit good chemical stability, thermal quenching resistance, and quantum efficiency, as well as narrow-band emission. Lastly, our findings provide important insights into the emission characteristics of rare-earth activators in phosphor hosts and a general strategy to the discovery of phosphors with a desired emission peak and bandwidth.« less

  15. Electronic structure descriptor for the discovery of narrow-band red-emitting phosphors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wang, Zhenbin; Chu, Iek -Heng; Zhou, Fei

    Narrow-band red-emitting phosphors are a critical component of phosphor-converted light-emitting diodes for highly efficient illumination-grade lighting. In this work, we report the discovery of a quantitative descriptor for narrow-band Eu 2+-activated emission identified through a comparison of the electronic structures of known narrow-band and broad-band phosphors. We find that a narrow emission bandwidth is characterized by a large splitting of more than 0.1 eV between the two highest Eu 2+ 4 f 7 bands. By incorporating this descriptor in a high-throughput first-principles screening of 2259 nitride compounds, we identify five promising new nitride hosts for Eu 2+-activated red-emitting phosphors thatmore » are predicted to exhibit good chemical stability, thermal quenching resistance, and quantum efficiency, as well as narrow-band emission. Lastly, our findings provide important insights into the emission characteristics of rare-earth activators in phosphor hosts and a general strategy to the discovery of phosphors with a desired emission peak and bandwidth.« less

  16. Multipoint Pacing versus conventional ICD in Patients with a Narrow QRS complex (MPP Narrow QRS trial): study protocol for a pilot randomized controlled trial.

    PubMed

    Gasparini, Maurizio; Galimberti, Paola; Bragato, Renato; Ghio, Stefano; Raineri, Claudia; Landolina, Maurizio; Chieffo, Enrico; Lunati, Maurizio; Mulargia, Ederina; Proclemer, Alessandro; Facchin, Domenico; Rordorf, Roberto; Vicentini, Alessandro; Marcantoni, Lina; Zanon, Francesco; Klersy, Catherine

    2016-12-03

    Despite an intensive search for predictors of the response to cardiac resynchronization therapy (CRT), the QRS duration remains the simplest and most robust predictor of a positive response. QRS duration of ≥ 130 ms is considered to be a prerequisite for CRT; however, some studies have shown that CRT may also be effective in heart failure (HF) patients with a narrow QRS (<130 ms). Since CRT can now be performed by pacing the left ventricle from multiple vectors via a single quadripolar lead, it is possible that multipoint pacing (MPP) might be effective in HF patients with a narrow QRS. This article reports the design of the MPP Narrow QRS trial, a prospective, randomized, multicenter, controlled feasibility study to investigate the efficacy of MPP using two LV pacing vectors in patients with a narrow QRS complex (100-130 ms). Fifty patients with a standard ICD indication will be enrolled and randomized (1:1) to either an MPP group or a Standard ICD group. All patients will undergo a low-dose dobutamine stress echo test and only those with contractile reserve will be included in the study and randomized. The primary endpoint will be the percentage of patients in each group that have reverse remodeling at 12 months, defined as a reduction in left ventricular end-systolic volume (LVESV) of >15% from the baseline. This feasibility study will determine whether MPP improves reverse remodeling, as compared with standard ICD, in HF patients who have a narrow QRS complex (100-130 ms). ClinicalTrials.gov, NCT02402816 . Registered on 25 March 2015.

  17. Narrow-Band Applications of Communications Satellites.

    ERIC Educational Resources Information Center

    Cowlan, Bert; Horowitz, Andrew

    This paper attempts to describe the advantages of "narrow-band" applications of communications satellites for education. It begins by discussing the general controversy surrounding the use of satellites in education, by placing the concern within the larger context of the general debate over the uses of new technologies in education, and by…

  18. Phosphorus-31 MRI of bones using quadratic echo line-narrowing

    NASA Astrophysics Data System (ADS)

    Frey, Merideth; Barrett, Sean; Insogna, Karl; Vanhouten, Joshua

    2012-02-01

    There is a great need to probe the internal composition of bone on the sub-0.1 mm length scale, both to study normal features and to look for signs of disease. Despite the obvious importance of the mineral fraction to the biomechanical properties of skeletal tissue, few non-destructive techniques are available to evaluate changes in its chemical structure and functional microarchitecture on the interior of bones. MRI would be an excellent candidate, but bone is a particularly challenging tissue to study given the relatively low water density and wider linewidths of its solid components. Recent fundamental research in quantum computing gave rise to a new NMR pulse sequence - the quadratic echo - that can be used to narrow the broad NMR spectrum of solids. This offers a new route to do high spatial resolution, 3D ^31P MRI of bone that complements conventional MRI and x-ray based techniques to study bone physiology and structure. We have used our pulse sequence to do 3D ^31P MRI of ex vivo bones with a spatial resolution of (sub-450 μm)^3, limited only by the specifications of a conventional 4 Tesla liquid-state MRI system. We will describe our plans to push this technique towards the factor of 1000 increase in spatial resolution imposed by fundamental limits.

  19. Search for Narrow Resonances in the b -Tagged Dijet Mass Spectrum in Proton-Proton Collisions at s = 8 TeV

    DOE PAGES

    Sirunyan, A. M.; Tumasyan, A.; Adam, W.; ...

    2018-05-14

    A search for narrow resonances decaying to bottom quark-antiquark pairs is presented, using a data sample of proton-proton collisions at s=8 TeV corresponding to an integrated luminosity of 19.7 fb -1. The search is extended to masses lower than those reached in typical searches for resonances decaying into jet pairs at the LHC, by taking advantage of triggers that identify jets originating from bottom quarks. No significant excess of events is observed above the background predictions. Limits are set on the product of cross section and branching fraction to bottom quarks for spin 0, 1, and 2 resonances in themore » mass range of 325–1200 GeV. These results improve on the limits for resonances decaying into jet pairs in the 325–500 GeV mass range.« less

  20. Search for Narrow Resonances in the b -Tagged Dijet Mass Spectrum in Proton-Proton Collisions at s = 8 TeV

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sirunyan, A. M.; Tumasyan, A.; Adam, W.

    A search for narrow resonances decaying to bottom quark-antiquark pairs is presented, using a data sample of proton-proton collisions at s=8 TeV corresponding to an integrated luminosity of 19.7 fb -1. The search is extended to masses lower than those reached in typical searches for resonances decaying into jet pairs at the LHC, by taking advantage of triggers that identify jets originating from bottom quarks. No significant excess of events is observed above the background predictions. Limits are set on the product of cross section and branching fraction to bottom quarks for spin 0, 1, and 2 resonances in themore » mass range of 325–1200 GeV. These results improve on the limits for resonances decaying into jet pairs in the 325–500 GeV mass range.« less

  1. Design, Construction, Demonstration and Delivery of an Automated Narrow Gap Welding System.

    DTIC Science & Technology

    1983-03-31

    evaluated on the Narrow Gap welding system. By using the combinational qas shielding assembly, it is now possible to reduce the gas flow rates to a value...AD-A145 496 DESIGN CONSTRUCTION DEMONSTRATION AND DE IVER OF AN AUTOMATED NARROW GAP WELDING SYSTEM(U) CRC AUTOMATIC WELDING CO HODSTON SX 31 MAR 83...STANDARDS-963 - A CRC REPORT NO. NAV A/W 7 0PHASE 3 REPORT ON SDESIGN, CONSTRUCTION, DEMONSTRATION AND DELIVERY OF AN AUTOMATED NARROW GAP WELDING

  2. Deep UV Narrow-Band Photodetector Based on Ion Beam Synthesized Indium Oxide Quantum Dots in Al2O3 Matrix.

    PubMed

    Rajamani, Saravanan; Arora, Kanika; Konakov, Anton; Belov, Alexey; Korolev, Dmitry; Nikolskaya, Alyona; Mikhaylov, Alexey N; Surodin, Sergey; Kryukov, Ruslan; Nikolichev, Dmitri; Sushkov, Artem; Pavlov, Dmitry; Tetelbaum, David; Kumar, Mukesh; Kumar, Mahesh

    2018-04-20

    Semiconductor quantum dots (QDs) have attracted tremendous attention owing to their novel electrical and optical properties due to the size dependent quantum confinement effects. This provides an advantage of tunable wavelength detection, which is essential to realize spectrally selective photodetectors. We report the fabrication and characterization of high performance narrow band ultraviolet photodetector (UV-B) based on In2O3 nanocrystals embedded in Al2O3 matrices. The In2O3 nanocrystals are synthesized in Al2O3 matrix by sequential implantation of In+ and N2+ ions and post-implantation annealing. The photodetector exhibits excellent optoelectronic performances with high spectral responsivity and external quantum efficiency. The spectral response showed a band-selective nature with a full width half maximum of ∼ 60 nm, and the responsivity reaches up to 70 A/W under 290 nm at 5 V bias. The corresponding rejection ratio to visible region was as high as 8400. The high performance of this photodetector makes it highly suitable for practical applications such as narrow-band spectrum-selective photodetectors. The device design based on ion-synthesized nanocrystals would provide a new approach for realizing a visible-blind photodetector. © 2018 IOP Publishing Ltd.

  3. Temporal intensity interferometry for characterization of very narrow spectral lines

    NASA Astrophysics Data System (ADS)

    Tan, P. K.; Kurtsiefer, C.

    2017-08-01

    Some stellar objects exhibit very narrow spectral lines in the visible range additional to their blackbody radiation. Natural lasing has been suggested as a mechanism to explain narrow lines in Wolf-Rayet stars. However, the spectral resolution of conventional astronomical spectrographs is still about two orders of magnitude too low to test this hypothesis. We want to resolve the linewidth of narrow spectral emissions in starlight. A combination of spectral filtering with single-photon-level temporal correlation measurements breaks the resolution limit of wavelength-dispersing spectrographs by moving the linewidth measurement into the time domain. We demonstrate in a laboratory experiment that temporal intensity interferometry can determine a 20-MHz-wide linewidth of Doppler-broadened laser light and identify a coherent laser light contribution in a blackbody radiation background.

  4. Fabrication and properties of ZnO/GaN heterostructure nanocolumnar thin film on Si (111) substrate

    PubMed Central

    2013-01-01

    Zinc oxide thin films have been obtained on bare and GaN buffer layer decorated Si (111) substrates by pulsed laser deposition (PLD), respectively. GaN buffer layer was achieved by a two-step method. The structure, surface morphology, composition, and optical properties of these thin films were investigated by X-ray diffraction, field emission scanning electron microscopy, infrared absorption spectra, and photoluminiscence (PL) spectra, respectively. Scanning electron microscopy images indicate that the flower-like grains were presented on the surface of ZnO thin films grown on GaN/Si (111) substrate, while the ZnO thin films grown on Si (111) substrate show the morphology of inclination column. PL spectrum reveals that the ultraviolet emission efficiency of ZnO thin film on GaN buffer layer is high, and the defect emission of ZnO thin film derived from Zni and Vo is low. The results demonstrate that the existence of GaN buffer layer can greatly improve the ZnO thin film on the Si (111) substrate by PLD techniques. PMID:23448090

  5. Fabrication and properties of ZnO/GaN heterostructure nanocolumnar thin film on Si (111) substrate.

    PubMed

    Wei, Xianqi; Zhao, Ranran; Shao, Minghui; Xu, Xijin; Huang, Jinzhao

    2013-02-28

    Zinc oxide thin films have been obtained on bare and GaN buffer layer decorated Si (111) substrates by pulsed laser deposition (PLD), respectively. GaN buffer layer was achieved by a two-step method. The structure, surface morphology, composition, and optical properties of these thin films were investigated by X-ray diffraction, field emission scanning electron microscopy, infrared absorption spectra, and photoluminiscence (PL) spectra, respectively. Scanning electron microscopy images indicate that the flower-like grains were presented on the surface of ZnO thin films grown on GaN/Si (111) substrate, while the ZnO thin films grown on Si (111) substrate show the morphology of inclination column. PL spectrum reveals that the ultraviolet emission efficiency of ZnO thin film on GaN buffer layer is high, and the defect emission of ZnO thin film derived from Zni and Vo is low. The results demonstrate that the existence of GaN buffer layer can greatly improve the ZnO thin film on the Si (111) substrate by PLD techniques.

  6. Effect of Refractive Index of Substrate on Fabrication and Optical Properties of Hybrid Au-Ag Triangular Nanoparticle Arrays

    PubMed Central

    Liu, Jing; Chen, Yushan; Cai, Haoyuan; Chen, Xiaoyi; Li, Changwei; Yang, Cheng-Fu

    2015-01-01

    In this study, the nanosphere lithography (NSL) method was used to fabricate hybrid Au-Ag triangular periodic nanoparticle arrays. The Au-Ag triangular periodic arrays were grown on different substrates, and the effect of the refractive index of substrates on fabrication and optical properties was systematically investigated. At first, the optical spectrum was simulated by the discrete dipole approximation (DDA) numerical method as a function of refractive indexes of substrates and mediums. Simulation results showed that as the substrates had the refractive indexes of 1.43 (quartz) and 1.68 (SF5 glass), the nanoparticle arrays would have better refractive index sensitivity (RIS) and figure of merit (FOM). Simulation results also showed that the peak wavelength of the extinction spectra had a red shift when the medium’s refractive index n increased. The experimental results also demonstrated that when refractive indexes of substrates were 1.43 and 1.68, the nanoparticle arrays and substrate had better adhesive ability. Meanwhile, we found the nanoparticles formed a large-scale monolayer array with the hexagonally close-packed structure. Finally, the hybrid Au-Ag triangular nanoparticle arrays were fabricated on quartz and SF5 glass substrates and their experiment extinction spectra were compared with the simulated results.

  7. A resonant absorption line in the ASCA spectrum of NGC 985?

    NASA Astrophysics Data System (ADS)

    Nicastro, F.; Fiore, F.; Brandt, N.; Reynolds, C. S.

    1999-01-01

    We present timing and spectral analyses of the ASCA observation of the Seyfert 1 galaxy NGC 985. The 0.6-10keV spectrum of this source is complex: large residuals are evident below 1keV when fitting the spectrum with a power-law model. Fitting a warm absorber model to the 0.6-2.5keV spectrum gives α=1.12+/-0.04, LogNWAH=21.97+/-0.08 and LogU=0.06+/-0.09, but the residuals continue to show a deficit of counts between 0.9 and 1keV. Adding an absorption line improves the fit, and the energy of the line is consistent with that of Kα NeIX-X resonant absorption lines. Hence, we confirm the presence of an ionized absorber along the line of sight to this source and interpret the further 1keV spectral feature as the first detection of a strong resonant absorption line associated with this system. The extrapolation of this model above 2.5keV produces large positive residuals above 3-4keV. Fitting the data with a broken power law plus warm absorber model gives an acceptable χ2 and Δα~0.5. A narrow iron line at 6.4keV (quasar frame) of equivalent width 138+64-110eV is also present in the ASCA data.

  8. The Peculiar Radio-loud Narrow Line Seyfert 1 Galaxy 1H 0323+342

    NASA Astrophysics Data System (ADS)

    Paliya, Vaidehi S.; Sahayanathan, S.; Parker, M. L.; Fabian, A. C.; Stalin, C. S.; Anjum, Ayesha; Pandey, S. B.

    2014-07-01

    We present a multiwavelength study of the radio-loud narrow-line Seyfert 1 galaxy (NLSy1) 1H 0323+342, detected by the Fermi Gamma-Ray Space Telescope. Multiband light curves show many orphan X-ray and optical flares having no corresponding γ-ray counterparts. Such anomalous variability behavior can be due to different locations of the emission region from the central source. During a large flare, a γ-ray flux doubling timescale as small as ~3 hr is noticed. We built spectral energy distributions (SEDs) during different activity states and modeled them using a one-zone leptonic model. The shape of the optical/UV component of the SEDs is dominated by accretion disk emission in all the activity states. In the X-ray band, significant thermal emission from the hot corona is inferred during quiescent and first flaring states; however, during subsequent flares, the nonthermal jet component dominates. The γ-ray emission in all the states can be well explained by inverse-Compton scattering of accretion disk photons reprocessed by the broad-line region. The source showed violent intra-night optical variability, coinciding with one of the high γ-ray activity states. An analysis of the overall X-ray spectrum fitted with an absorbed power-law plus relativistic reflection component hints at the presence of an Fe Kα line and returns a high black hole spin value of a = 0.96 ± 0.14. We argue that 1H 0323+342 possesses dual characteristics, akin to both flat-spectrum radio quasars (FSRQs) and radio-quiet NLSy1 galaxies, though at a low jet power regime compared to powerful FSRQs.

  9. Narrow-line magneto-optical cooling and trapping of strongly magnetic atoms.

    PubMed

    Berglund, Andrew J; Hanssen, James L; McClelland, Jabez J

    2008-03-21

    Laser cooling on weak transitions is a useful technique for reaching ultracold temperatures in atoms with multiple valence electrons. However, for strongly magnetic atoms a conventional narrow-line magneto-optical trap (MOT) is destabilized by competition between optical and magnetic forces. We overcome this difficulty in Er by developing an unusual narrow-line MOT that balances optical and magnetic forces using laser light tuned to the blue side of a narrow (8 kHz) transition. The trap population is spin polarized with temperatures reaching below 2 muK. Our results constitute an alternative method for laser cooling on weak transitions, applicable to rare-earth-metal and metastable alkaline earth elements.

  10. 78 FR 23845 - Drawbridge Operation Regulations; Narrow Bay, Smith Point, NY

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-23

    ... Operation Regulations; Narrow Bay, Smith Point, NY AGENCY: Coast Guard, DHS. ACTION: Notice of temporary... deviation from the regulation governing the operation of the Smith Point Bridge, mile 6.1, across Narrow Bay, between Smith Point and Fire Island, New York. The deviation is necessary to facilitate the Smith Point...

  11. Multiwavelength Monitoring of the Enigmatic Narrow-Line Seyfert 1 PMN J0948+0022 in 2009 March-July

    DOE PAGES

    Abdo, A. A.; Ackermann, M.; Ajello, M.; ...

    2009-11-25

    For this research, following the recent discovery of γ rays from the radio-loud narrow-line Seyfert 1 galaxy PMN J0948+0022 (z = 0.5846), we started a multiwavelength campaign from radio to γ rays, which was carried out between the end of 2009 March and the beginning of July. The source displayed activity at all the observed wavelengths: a general decreasing trend from optical to γ-ray frequencies was followed by an increase of radio emission after less than two months from the peak of the γ-ray emission. The largest flux change, about a factor of about 4, occurred in the X-ray band.more » The smallest was at ultraviolet and near-infrared frequencies, where the rate of the detected photons dropped by a factor 1.6-1.9. At optical wavelengths, where the sampling rate was the highest, it was possible to observe day scale variability, with flux variations up to a factor of about 3. The behavior of PMN J0948+0022 observed in this campaign and the calculated power carried out by its jet in the form of protons, electrons, radiation, and magnetic field are quite similar to that of blazars, specifically of flat-spectrum radio quasars. In conclusion, these results confirm the idea that radio-loud narrow-line Seyfert 1 galaxies host relativistic jets with power similar to that of average blazars.« less

  12. Ultra-narrow-linewidth Brillouin/erbium fiber laser

    NASA Astrophysics Data System (ADS)

    Chen, Mo; Wang, Chenyu; Wang, Jianfei; Luo, Hong; Meng, Zhou

    2018-02-01

    Ultra-narrow-linewidth lasers are of great interest in many applications, such as precise spectroscopy, optical communications, and sensors. Stimulated Brillouin scattering (SBS), as one of the main nonlinear effects in fibers, is capable of generating narrow-linewidth light emission. We establish a compact Brillouin/erbium fiber laser (BEFL) utilizing 4-m erbium-doped fiber as both the Brillouin gain and linear media. A 360-kHz-linewidth laser diode is injected into the cavity as the Brillouin pump (BP) light and generates Brillouin Stokes lasing light. Both of the phase noise of the BP and BEFL output are measured by a high-accuracy unbalanced Michelson interferometer. It is demonstrated that 53- dB phase noise reduction is achieved after the BP is transferred into Brillouin Stokes emission. The linewidth of the BEFL is indicated at Hz-range by both calculation and experiment.

  13. Terahertz-radiation generation in low-temperature InGaAs epitaxial films on (100) and (411) InP substrates

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Galiev, G. B., E-mail: galiev-galib@mail.ru; Grekhov, M. M.; Kitaeva, G. Kh.

    2017-03-15

    The spectrum and waveforms of broadband terahertz-radiation pulses generated by low-temperature In{sub 0.53}Ga{sub 0.47}As epitaxial films under femtosecond laser pumping are investigated by terahertz time-resolved spectroscopy. The In{sub 0.53}Ga{sub 0.47}As films are fabricated by molecular-beam epitaxy at a temperature of 200°C under different arsenic pressures on (100)-oriented InP substrates and, for the first time, on (411)A InP substrates. The surface morphology of the samples is studied by atomic-force microscopy and the structural quality is established by high-resolution X-ray diffraction analysis. It is found that the amplitude of terahertz radiation from the LT-InGaAs layers on the (411)A InP substrates exceeds thatmore » from similar layers formed on the (100) InP substrates by a factor of 3–5.« less

  14. Relationships between substrate, surface characteristics, and vegetation in an initial ecosystem

    NASA Astrophysics Data System (ADS)

    Biber, P.; Seifert, S.; Zaplata, M. K.; Schaaf, W.; Pretzsch, H.; Fischer, A.

    2013-12-01

    We investigated surface and vegetation dynamics in the artificial initial ecosystem "Chicken Creek" (Lusatia, Germany) in the years 2006-2011 across a wide spectrum of empirical data. We scrutinized three overarching hypotheses concerning (1) the relations between initial geomorphological and substrate characteristics with surface structure and terrain properties, (2) the effects of the latter on the occurrence of grouped plant species, and (3) vegetation density effects on terrain surface change. Our data comprise and conflate annual vegetation monitoring results, biennial terrestrial laser scans (starting in 2008), annual groundwater levels, and initially measured soil characteristics. The empirical evidence mostly confirms the hypotheses, revealing statistically significant relations for several goal variables: (1) the surface structure properties, local rill density, local relief energy and terrain surface height change; (2) the cover of different plant groups (annual, herbaceous, grass-like, woody, Fabaceae), and local vegetation height; and (3) terrain surface height change showed significant time-dependent relations with a variable that proxies local plant biomass. Additionally, period specific effects (like a calendar-year optimum effect for the occurrence of Fabaceae) were proven. Further and beyond the hypotheses, our findings on the spatiotemporal dynamics during the system's early development grasp processes which generally mark the transition from a geo-hydro-system towards a bio-geo-hydro system (weakening geomorphology effects on substrate surface dynamics, while vegetation effects intensify with time), where pure geomorphology or substrate feedbacks are changing into vegetation-substrate feedback processes.

  15. The Effect of High N-DOPED Anatase TiO2 on the Band Gap Narrowing and Redshift by First-Principles

    NASA Astrophysics Data System (ADS)

    Hou, Qingyu; Jin, Yongjun; Ying, Chun; Zhao, Erjun; Zhang, Yue; Dong, Hongying

    2012-10-01

    Anatase TiO2 supercells were studied by first-principles, in which one was undoped and another three were high N-doping. Partial densities of states, band structure, population and absorption spectrum were calculated. The calculated results indicated that in the condition of TiO2-xNx (x = 0.0625, 0.125, 0.25), the higher the doping concentration is, the shorter will be the lattice parameters parallel to the direction of c-axis. The strength of covalent bond significantly varied. The formation energy increases at first, and then decreases. The doping models become less stable as N-doping concentration increases. Meanwhile, the narrower the band gap is, the more significant will be the redshift, which is in agreement with the experimental results.

  16. A technique for production of nanocrystalline cellulose with a narrow size distribution

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bai, Wen; Holbery, James D.; Li, Kaichang

    2009-02-01

    Nanocrystalline cellulose (NCC) was prepared by sulfuric acid hydrolysis of microcrystalline cellulose. A differential centrifugation technique was studied to obtain NCC whiskers with a narrow size distribution. It was shown that the volume of NCC in different fractions had an inverse relationship with relative centrifugal force (RCF). The length of NCC whiskers was also fractionized by differential RCF. The aspect ratio of NCC in different fractions had a relatively narrow range. This technique provides an easy way of producing NCC whiskers with a narrow size distribution.

  17. Ischemic Ventricular Tachycardia Presenting as a Narrow Complex Tachycardia

    PubMed Central

    Page, Stephen P; Watts, Troy; Yeo, Wee Tiong; Mehul, Dhinoja

    2014-01-01

    This report describes a patient presenting with a narrow complex tachycardia in the context of prior myocardial infarction and impaired ventricular function. Electrophysiological studies confirmed ventricular tachycardia and activation and entrainment mapping demonstrated a critical isthmus within an area of scar involving the His-Purkinje system accounting for the narrow QRS morphology. This very rare case shares some similarities with upper septal ventricular tachycardia seen in patients with structurally normal hearts, but to our knowledge has not been seen previously in patients with ischemic heart disease. PMID:25057222

  18. Adverse effects of prohibiting narrow provider networks.

    PubMed

    Howard, David H

    2014-08-14

    Many insurers participating in the new insurance exchanges are controlling costs by offering plans with narrow provider networks. Proposed regulations would promote network adequacy, but a pro-provider stance may not be inherently pro-consumer or even pro-patient.

  19. Spatially Mapping Energy Transfer from Single Plasmonic Particles to Semiconductor Substrates via STEM/EELS.

    PubMed

    Li, Guoliang; Cherqui, Charles; Bigelow, Nicholas W; Duscher, Gerd; Straney, Patrick J; Millstone, Jill E; Masiello, David J; Camden, Jon P

    2015-05-13

    Energy transfer from plasmonic nanoparticles to semiconductors can expand the available spectrum of solar energy-harvesting devices. Here, we spatially and spectrally resolve the interaction between single Ag nanocubes with insulating and semiconducting substrates using electron energy-loss spectroscopy, electrodynamics simulations, and extended plasmon hybridization theory. Our results illustrate a new way to characterize plasmon-semiconductor energy transfer at the nanoscale and bear impact upon the design of next-generation solar energy-harvesting devices.

  20. Allosteric Control of Substrate Specificity of the Escherichia coli ADP-glucose Pyrophosphorylase

    NASA Astrophysics Data System (ADS)

    Ebrecht, Ana C.; Solamen, Ligin; Hill, Benjamin L.; Iglesias, Alberto A.; Olsen, Kenneth W.; Ballicora, Miguel A.

    2017-06-01

    The substrate specificity of enzymes is crucial to control the fate of metabolites to different pathways. However, there is growing evidence that many enzymes can catalyze alternative reactions. This promiscuous behavior has important implications in protein evolution and the acquisition of new functions. The question is how the undesirable outcomes of in vivo promiscuity can be prevented. ADP-glucose pyrophosphorylase from Escherichia coli is an example of an enzyme that needs to select the correct substrate from a broad spectrum of alternatives. This selection will guide the flow of carbohydrate metabolism towards the synthesis of reserve polysaccharides. Here, we show that the allosteric activator fructose-1,6-bisphosphate plays a role in such selection by increasing the catalytic efficiency of the enzyme towards the use of ATP rather than other nucleotides. In the presence of fructose-1,6-bisphosphate, the kcat/S0.5 for ATP was near 600-fold higher that other nucleotides, whereas in the absence of activator was only 3-fold higher. We propose that the allosteric regulation of certain enzymes is an evolutionary mechanism of adaptation for the selection of specific substrates.

  1. Utility of Thin-Film Solar Cells on Flexible Substrates for Space Power

    NASA Technical Reports Server (NTRS)

    Dickman, J. E.; Hepp, A. F.; Morel, D. L.; Ferekides, C. S.; Tuttle, J. R.; Hoffman, D. J.; Dhere, N. G.

    2004-01-01

    The thin-film solar cell program at NASA GRC is developing solar cell technologies for space applications which address two critical metrics: specific power (power per unit mass) and launch stowed volume. To be competitive for many space applications, an array using thin film solar cells must significantly increase specific power while reducing stowed volume when compared to the present baseline technology utilizing crystalline solar cells. The NASA GRC program is developing two approaches. Since the vast majority of the mass of a thin film solar cell is in the substrate, a thin film solar cell on a very lightweight flexible substrate (polymer or metal films) is being developed as the first approach. The second approach is the development of multijunction thin film solar cells. Total cell efficiency can be increased by stacking multiple cells having bandgaps tuned to convert the spectrum passing through the upper cells to the lower cells. Once developed, the two approaches will be merged to yield a multijunction, thin film solar cell on a very lightweight, flexible substrate. The ultimate utility of such solar cells in space require the development of monolithic interconnections, lightweight array structures, and ultra-lightweight support and deployment techniques.

  2. Novel SiO2-deposited CaF2 substrate for vibrational sum-frequency generation (SFG) measurements of chemisorbed monolayers in an aqueous environment.

    PubMed

    Padermshoke, Adchara; Konishi, Shouta; Ara, Masato; Tada, Hirokazu; Ishibashi, Taka-Aki

    2012-06-01

    A novel SiO(2)-deposited CaF(2) (SiO(2)/CaF(2)) substrate for measuring vibrational sum-frequency generation (SFG) spectra of silane-based chemisorbed monolayers in aqueous media has been developed. The substrate is suitable for silanization and transparent over a broad range of the infrared (IR) probe. The present work demonstrates the practical application of the SiO(2)/CaF(2) substrate and, to our knowledge, the first SFG spectrum at the solid/water interface of a silanized monolayer observed over the IR fingerprint region (1780-1400 cm(-1)) using a back-side probing geometry. This new substrate can be very useful for SFG studies of various chemisorbed organic molecules, particularly biological compounds, in aqueous environments.

  3. Multiwavelength observations of the γ-ray-emitting narrow-line Seyfert 1 PMN J0948+0022 in 2011

    DOE PAGES

    D'Ammando, F.; Larsson, J.; Orienti, M.; ...

    2014-01-28

    Here, we report on radio-to-γ-ray observations during 2011 May–September of PMN J0948+0022, the first narrow-line Seyfert 1 (NLSy1) galaxy detected in γ-rays by Fermi-Large Area Telescope. Strong variability was observed in γ-rays, with two flaring periods peaking on 2011 June 20 and July 28. The variability observed in optical and near-infrared seems to have no counterpart in γ-rays. The difference in behaviour could be related to a bending and inhomogeneous jet or a turbulent extreme multicell scenario. The radio spectra showed a variability pattern typical of relativistic jets. The XMM spectrum shows that the emission from the jet dominates abovemore » ~2 keV, while a soft X-ray excess is evident in the low-energy part of the X-ray spectrum. Models where the soft emission is partly produced by blurred reflection or Comptonization of the thermal disc emission provide good fits to the data. The X-ray spectral slope is similar to that found in radio-quiet NLSy1, suggesting that a standard accretion disc is present, as expected from the high accretion rate. Except for the soft X-ray excess, unusual in jet-dominated active galactic nuclei, PMN J0948+0022, shows all characteristics of the blazar class.« less

  4. Assessing the Utility of Compound Trait Estimates of Narrow Personality Traits.

    PubMed

    Credé, Marcus; Harms, Peter D; Blacksmith, Nikki; Wood, Dustin

    2016-01-01

    It has been argued that approximations of narrow traits can be made through linear combinations of broad traits such as the Big Five personality traits. Indeed, Hough and Ones ( 2001 ) used a qualitative analysis of scale content to arrive at a taxonomy of how Big Five traits might be combined to approximate various narrow traits. However, the utility of such compound trait approximations has yet to be established beyond specific cases such as integrity and customer service orientation. Using data from the Eugene-Springfield Community Sample (Goldberg, 2008 ), we explore the ability of linear composites of scores on Big Five traits to approximate scores on 127 narrow trait measures from 5 well-known non-Big-Five omnibus measures of personality. Our findings indicate that individuals' standing on more than 30 narrow traits can be well estimated from 3 different types of linear composites of scores on Big Five traits without a substantial sacrifice in criterion validity. We discuss theoretical accounts for why such relationships exist as well as the theoretical and practical implications of these findings for researchers and practitioners.

  5. Grassy Narrows Reserve: Mercury Pollution, Social Disruption, and Natural Resources: A Question of Autonomy.

    ERIC Educational Resources Information Center

    Vecsey, Christopher

    1987-01-01

    Presents chronological socio-economic account of Grassy Narrows Reserve, focusing on the 1962-1970 mercury pollution that poisoned the reserve's river system and on resulting negotiations between the Ojibway people of Grassy Narrows, the government, and the polluting company. Examines the question of Grassy Narrows people gaining autonomy over the…

  6. Einstein-Podolsky-Rosen Entanglement of Narrow-Band Photons from Cold Atoms.

    PubMed

    Lee, Jong-Chan; Park, Kwang-Kyoon; Zhao, Tian-Ming; Kim, Yoon-Ho

    2016-12-16

    Einstein-Podolsky-Rosen (EPR) entanglement introduced in 1935 deals with two particles that are entangled in their positions and momenta. Here we report the first experimental demonstration of EPR position-momentum entanglement of narrow-band photon pairs generated from cold atoms. By using two-photon quantum ghost imaging and ghost interference, we demonstrate explicitly that the narrow-band photon pairs violate the separability criterion, confirming EPR entanglement. We further demonstrate continuous variable EPR steering for positions and momenta of the two photons. Our new source of EPR-entangled narrow-band photons is expected to play an essential role in spatially multiplexed quantum information processing, such as, storage of quantum correlated images, quantum interface involving hyperentangled photons, etc.

  7. Einstein-Podolsky-Rosen Entanglement of Narrow-Band Photons from Cold Atoms

    NASA Astrophysics Data System (ADS)

    Lee, Jong-Chan; Park, Kwang-Kyoon; Zhao, Tian-Ming; Kim, Yoon-Ho

    2016-12-01

    Einstein-Podolsky-Rosen (EPR) entanglement introduced in 1935 deals with two particles that are entangled in their positions and momenta. Here we report the first experimental demonstration of EPR position-momentum entanglement of narrow-band photon pairs generated from cold atoms. By using two-photon quantum ghost imaging and ghost interference, we demonstrate explicitly that the narrow-band photon pairs violate the separability criterion, confirming EPR entanglement. We further demonstrate continuous variable EPR steering for positions and momenta of the two photons. Our new source of EPR-entangled narrow-band photons is expected to play an essential role in spatially multiplexed quantum information processing, such as, storage of quantum correlated images, quantum interface involving hyperentangled photons, etc.

  8. Experimental study on occupant evacuation in narrow seat aisle

    NASA Astrophysics Data System (ADS)

    Huang, Shenshi; Lu, Shouxiang; Lo, Siuming; Li, Changhai; Guo, Yafei

    2018-07-01

    Narrow seat aisle is an important area in the train car interior due to the large passenger population, however evacuation therein has not gained enough concerns. In this experimental study, the occupant evacuation of the narrow seat aisle area is investigated, with the aisle width of 0.4-0.6 m and the evacuation direction of forward and backward. The evacuation behaviors are analyzed based on the video record, and the discussion is carried out in the aspect of evacuation time, crowdedness, evacuation order, and aisle conflicts. The result shows that with the increasing aisle width, total evacuation time and the average specific evacuation rate decrease. The aisle is crowded for some time, with a large linear occupant densities. The evacuation order of each occupant is mainly related to the seat position. Moreover, it is found that the aisle conflicts can be well described by Burstedde's model. This study gives a useful benchmark for evacuation simulation of narrow seat aisle, and provides reference to safety design of seat area in train cars.

  9. Inoculation of sphagnum-based soil substrate with entomopathogenic fungus Isaria fumosorosea (Hypocreales: Cordycipitaceae)

    NASA Astrophysics Data System (ADS)

    Zemek, Rostislav; Konopická, Jana; Bohatá, Andrea

    2018-04-01

    Convenient ecological alternative to broad-spectrum chemical pesticides is the utilization of natural enemies, like predators, parasitoids and microorganisms. A substantial number of microbial biopesticides based on entomopathogenic fungi have been developed worldwide since 1960s. Beauveria bassiana (Balsamo-Crivelli) Vuillemin, Metarhizium anisopliae (Metchnikoff) Sorokin, Isaria fumosorosea (Wize), and B. brongniartii (Saccardo) Petch are the most common species used in commercially produced mycopesticides. Besides direct biological pest control, these fungi could be also used in preventive application programs, particularly in ornamental or nursery plants to provide better control against pests. The aim of the present study was to investigate potential of pre-colonization of sphagnum-based soil substrate with I. fumosorosea strain CCM 8367 which was found earlier to be highly virulent against several pest species. We developed simple laboratory apparatus for application of fungal spore suspension into the substrate. Suspension was prepared from blastospores obtained by submerged cultivation on potato dextrose broth (PDB) medium using an orbital shaker. Inoculated substrate was placed into plastic bags and stored at constant temperature for six months. Every month, samples were analyzed for concentration of colony forming units (CFU) by elution and selective medium technique. The results showed that at 20°C the fungus successfully colonized the soil substrate and persisted there although the mean concentration slightly decreased from 5.89×104 to 2.76×104 CFU per milliliter of substrate during the experiment. Temperature 30°C had negative effect on survival of the fungus and is not recommended for long-term storage of pre-inoculated substrate. We can conclude that I. fumosorosea-colonized substrate can be convenient for preventive and permanent protection of various plants against soil-dwelling pests.

  10. The executive prominent/memory prominent spectrum in Alzheimer's disease is highly heritable.

    PubMed

    Mez, Jesse; Mukherjee, Shubhabrata; Thornton, Timothy; Fardo, David W; Trittschuh, Emily; Sutti, Sheila; Sherva, Richard; Kauwe, John S; Naj, Adam C; Beecham, Gary W; Gross, Alden; Saykin, Andrew J; Green, Robert C; Crane, Paul K

    2016-05-01

    Late-onset Alzheimer's disease (LOAD) can present heterogeneously, with several subtypes recognized, including dysexecutive AD. One way to identify people with dysexecutive AD is to consider the difference between memory and executive functioning, which we refer to as the executive prominent/memory prominent spectrum. We aimed to determine if this spectrum was heritable. We used neuropsychological and genetic data from people with mild LOAD (Clinical Dementia Rating 0.5 or 1.0) from the National Alzheimer's Coordinating Center and the Alzheimer's Disease Neuroimaging Initiative. We cocalibrated the neuropsychological data to obtain executive functioning and memory scores and used their difference as a continuous phenotype to calculate its heritability overall and by chromosome. Narrow-sense heritability of the difference between memory and executive functioning scores was 0.68 (standard error 0.12). Single nucleotide polymorphisms on chromosomes 1, 2, 4, 11, 12, and 18 explained the largest fraction of phenotypic variance, with signals from each chromosome accounting for 5%-7%. The chromosomal pattern of heritability differed substantially from that of LOAD itself. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. Performance characteristics of narrow linewidth fiber laser pumped mid-IR difference frequency mixing light source for methane detection

    NASA Technical Reports Server (NTRS)

    Ashizawa, Hiroaki; Ohara, Shinobu; Yamaguchi, Shigeru; Takahashi, Masao; Endo, Masamori; Nanri, Kenzo; Fujioka, Tomoo; Tittel, Frank K.

    2003-01-01

    A high-power, narrow-linewidth Yb fiber laser with a fiber Bragg grating (FBG) pumped difference frequency generation (DFG) in a periodically poled lithium niobate (PPLN) crystal was investigated in detail. A mid-IR power of approximately 2.3 microW at 3.3 micrometers with a slope efficiency of 0.85 mW/W2 was achieved. A Doppler-broadened absorption spectrum of CH4 at 3038.497 cm-1 (3.2911 micrometers) was obtained with a 0.1-m long-gas cell at a pressure of 133 Pa. The linewidth of the DFG source was evaluated to be less than 96 MHz from the observed spectral linewidth. Real-time monitoring of CH4 (approximately 1.78 ppm) in ambient air in a multipass cell which has an optical path length of 10 m was also demonstrated.

  12. Observation of soft X-ray spectra from a Seyfert 1 and a narrow emission-line galaxy

    NASA Technical Reports Server (NTRS)

    Singh, K. P.; Garmire, G. P.; Nousek, J.

    1985-01-01

    The 0.2-40 keV X-ray spectra of the Seyfert 1 galaxy Mrk 509 and the narrow emission-line galaxy NGC 2992 are analyzed. The results suggest the presence of a steep soft X-ray component in Mrk 509 in addition to the well-known Gamma = 1.7 component found in other active galactic nuclei in the 2-40 keV energy range. The soft X-ray component is interpreted as due to thermal emission from a hot gas, probably associated with the highly ionized gas observed to be outflowing from the galaxy. The X-ray spectrum of NGC 2992 does not show any steepening in the soft X-ray band and is consistent with a single power law (Gamma = 1.78) with very low absorbing column density of 4 x 10 to the 21st/sq cm. A model with partial covering of the nuclear X-ray source is preferred, however, to a simple model with a single power law and absorption.

  13. Rapid water transportation through narrow one-dimensional channels by restricted hydrogen bonds.

    PubMed

    Ohba, Tomonori; Kaneko, Katsumi; Endo, Morinobu; Hata, Kenji; Kanoh, Hirofumi

    2013-01-29

    Water plays an important role in controlling chemical reactions and bioactivities. For example, water transportation through water channels in a biomembrane is a key factor in bioactivities. However, molecular-level mechanisms of water transportation are as yet unknown. Here, we investigate water transportation through narrow and wide one-dimensional (1D) channels on the basis of water-vapor adsorption rates and those determined by molecular dynamics simulations. We observed that water in narrow 1D channels was transported 3-5 times faster than that in wide 1D channels, although the narrow 1D channels provide fewer free nanospaces for water transportation. This rapid transportation is attributed to the formation of fewer hydrogen bonds between water molecules adsorbed in narrow 1D channels. The water-transportation mechanism provides the possibility of rapid communication through 1D channels and will be useful in controlling reactions and activities in water systems.

  14. Plant Growth Absorption Spectrum Mimicking Light Sources

    PubMed Central

    Jou, Jwo-Huei; Lin, Ching-Chiao; Li, Tsung-Han; Li, Chieh-Ju; Peng, Shiang-Hau; Yang, Fu-Chin; Justin Thomas, K. R.; Kumar, Dhirendra; Chi, Yun; Hsu, Ban-Dar

    2015-01-01

    Plant factories have attracted increasing attention because they can produce fresh fruits and vegetables free from pesticides in all weather. However, the emission spectra from current light sources significantly mismatch the spectra absorbed by plants. We demonstrate a concept of using multiple broad-band as well as narrow-band solid-state lighting technologies to design plant-growth light sources. Take an organic light-emitting diode (OLED), for example; the resulting light source shows an 84% resemblance with the photosynthetic action spectrum as a twin-peak blue dye and a diffused mono-peak red dye are employed. This OLED can also show a greater than 90% resemblance as an additional deeper red emitter is added. For a typical LED, the resemblance can be improved to 91% if two additional blue and red LEDs are incorporated. The approach may facilitate either an ideal use of the energy applied for plant growth and/or the design of better light sources for growing different plants. PMID:28793503

  15. Search for Narrow Resonances in the b -Tagged Dijet Mass Spectrum in Proton-Proton Collisions at √{s }=8 TeV

    NASA Astrophysics Data System (ADS)

    Sirunyan, A. M.; Tumasyan, A.; Adam, W.; Ambrogi, F.; Asilar, E.; Bergauer, T.; Brandstetter, J.; Brondolin, E.; Dragicevic, M.; Erö, J.; Escalante Del Valle, A.; Flechl, M.; Friedl, M.; Frühwirth, R.; Ghete, V. M.; Grossmann, J.; Hrubec, J.; Jeitler, M.; König, A.; Krammer, N.; Krätschmer, I.; Liko, D.; Madlener, T.; Mikulec, I.; Pree, E.; Rad, N.; Rohringer, H.; Schieck, J.; Schöfbeck, R.; Spanring, M.; Spitzbart, D.; Taurok, A.; Waltenberger, W.; Wittmann, J.; Wulz, C.-E.; Zarucki, M.; Chekhovsky, V.; Mossolov, V.; Suarez Gonzalez, J.; De Wolf, E. A.; Di Croce, D.; Janssen, X.; Lauwers, J.; Pieters, M.; Van De Klundert, M.; Van Haevermaet, H.; Van Mechelen, P.; Van Remortel, N.; Abu Zeid, S.; Blekman, F.; D'Hondt, J.; De Bruyn, I.; De Clercq, J.; Deroover, K.; Flouris, G.; Lontkovskyi, D.; Lowette, S.; Marchesini, I.; Moortgat, S.; Moreels, L.; Python, Q.; Skovpen, K.; Tavernier, S.; Van Doninck, W.; Van Mulders, P.; Van Parijs, I.; Beghin, D.; Bilin, B.; Brun, H.; Clerbaux, B.; De Lentdecker, G.; Delannoy, H.; Dorney, B.; Fasanella, G.; Favart, L.; Goldouzian, R.; Grebenyuk, A.; Kalsi, A. K.; Lenzi, T.; Luetic, J.; Seva, T.; Starling, E.; Vander Velde, C.; Vanlaer, P.; Vannerom, D.; Yonamine, R.; Cornelis, T.; Dobur, D.; Fagot, A.; Gul, M.; Khvastunov, I.; Poyraz, D.; Roskas, C.; Trocino, D.; Tytgat, M.; Verbeke, W.; Vermassen, B.; Vit, M.; Zaganidis, N.; Bakhshiansohi, H.; Bondu, O.; Brochet, S.; Bruno, G.; Caputo, C.; Caudron, A.; David, P.; De Visscher, S.; Delaere, C.; Delcourt, M.; Francois, B.; Giammanco, A.; Krintiras, G.; Lemaitre, V.; Magitteri, A.; Mertens, A.; Musich, M.; Piotrzkowski, K.; Quertenmont, L.; Saggio, A.; Vidal Marono, M.; Wertz, S.; Zobec, J.; Aldá Júnior, W. L.; Alves, F. L.; Alves, G. A.; Brito, L.; Correia Silva, G.; Hensel, C.; Moraes, A.; Pol, M. E.; Rebello Teles, P.; Belchior Batista Das Chagas, E.; Carvalho, W.; Chinellato, J.; Coelho, E.; Da Costa, E. M.; Da Silveira, G. G.; De Jesus Damiao, D.; Fonseca De Souza, S.; Malbouisson, H.; Medina Jaime, M.; Melo De Almeida, M.; Mora Herrera, C.; Mundim, L.; Nogima, H.; Sanchez Rosas, L. J.; Santoro, A.; Sznajder, A.; Thiel, M.; Tonelli Manganote, E. J.; Torres Da Silva De Araujo, F.; Vilela Pereira, A.; Ahuja, S.; Bernardes, C. A.; Calligaris, L.; Tomei, T. R. Fernandez Perez; Gregores, E. M.; Mercadante, P. G.; Novaes, S. F.; Padula, Sandra S.; Romero Abad, D.; Ruiz Vargas, J. C.; Aleksandrov, A.; Hadjiiska, R.; Iaydjiev, P.; Marinov, A.; Misheva, M.; Rodozov, M.; Shopova, M.; Sultanov, G.; Dimitrov, A.; Litov, L.; Pavlov, B.; Petkov, P.; Fang, W.; Gao, X.; Yuan, L.; Ahmad, M.; Bian, J. G.; Chen, G. M.; Chen, H. S.; Chen, M.; Chen, Y.; Jiang, C. H.; Leggat, D.; Liao, H.; Liu, Z.; Romeo, F.; Shaheen, S. M.; Spiezia, A.; Tao, J.; Wang, C.; Wang, Z.; Yazgan, E.; Zhang, H.; Zhao, J.; Ban, Y.; Chen, G.; Li, J.; Li, Q.; Liu, S.; Mao, Y.; Qian, S. J.; Wang, D.; Xu, Z.; Wang, Y.; Avila, C.; Cabrera, A.; Carrillo Montoya, C. A.; Chaparro Sierra, L. F.; Florez, C.; González Hernández, C. F.; Segura Delgado, M. A.; Courbon, B.; Godinovic, N.; Lelas, D.; Puljak, I.; Ribeiro Cipriano, P. M.; Sculac, T.; Antunovic, Z.; Kovac, M.; Brigljevic, V.; Ferencek, D.; Kadija, K.; Mesic, B.; Starodumov, A.; Susa, T.; Ather, M. W.; Attikis, A.; Mavromanolakis, G.; Mousa, J.; Nicolaou, C.; Ptochos, F.; Razis, P. A.; Rykaczewski, H.; Finger, M.; Finger, M.; Carrera Jarrin, E.; Assran, Y.; Elgammal, S.; Mahmoud, M. A.; Bhowmik, S.; Dewanjee, R. K.; Kadastik, M.; Perrini, L.; Raidal, M.; Veelken, C.; Eerola, P.; Kirschenmann, H.; Pekkanen, J.; Voutilainen, M.; Havukainen, J.; Heikkilä, J. K.; Järvinen, T.; Karimäki, V.; Kinnunen, R.; Lampén, T.; Lassila-Perini, K.; Laurila, S.; Lehti, S.; Lindén, T.; Luukka, P.; Mäenpää, T.; Siikonen, H.; Tuominen, E.; Tuominiemi, J.; Tuuva, T.; Besancon, M.; Couderc, F.; Dejardin, M.; Denegri, D.; Faure, J. L.; Ferri, F.; Ganjour, S.; Ghosh, S.; Givernaud, A.; Gras, P.; Hamel de Monchenault, G.; Jarry, P.; Leloup, C.; Locci, E.; Machet, M.; Malcles, J.; Negro, G.; Rander, J.; Rosowsky, A.; Sahin, M. Ö.; Titov, M.; Abdulsalam, A.; Amendola, C.; Antropov, I.; Baffioni, S.; Beaudette, F.; Busson, P.; Cadamuro, L.; Charlot, C.; Granier de Cassagnac, R.; Jo, M.; Kucher, I.; Lisniak, S.; Lobanov, A.; Martin Blanco, J.; Nguyen, M.; Ochando, C.; Ortona, G.; Paganini, P.; Pigard, P.; Salerno, R.; Sauvan, J. B.; Sirois, Y.; Stahl Leiton, A. G.; Yilmaz, Y.; Zabi, A.; Zghiche, A.; Agram, J.-L.; Andrea, J.; Bloch, D.; Brom, J.-M.; Chabert, E. C.; Collard, C.; Conte, E.; Coubez, X.; Drouhin, F.; Fontaine, J.-C.; Gelé, D.; Goerlach, U.; Jansová, M.; Juillot, P.; Le Bihan, A.-C.; Tonon, N.; Van Hove, P.; Gadrat, S.; Beauceron, S.; Bernet, C.; Boudoul, G.; Chanon, N.; Chierici, R.; Contardo, D.; Depasse, P.; El Mamouni, H.; Fay, J.; Finco, L.; Gascon, S.; Gouzevitch, M.; Grenier, G.; Ille, B.; Lagarde, F.; Laktineh, I. B.; Lattaud, H.; Lethuillier, M.; Mirabito, L.; Pequegnot, A. L.; Perries, S.; Popov, A.; Sordini, V.; Vander Donckt, M.; Viret, S.; Zhang, S.; Toriashvili, T.; Tsamalaidze, Z.; Autermann, C.; Feld, L.; Kiesel, M. K.; Klein, K.; Lipinski, M.; Preuten, M.; Rauch, M. P.; Schomakers, C.; Schulz, J.; Teroerde, M.; Wittmer, B.; Zhukov, V.; Albert, A.; Duchardt, D.; Endres, M.; Erdmann, M.; Erdweg, S.; Esch, T.; Fischer, R.; Güth, A.; Hebbeker, T.; Heidemann, C.; Hoepfner, K.; Knutzen, S.; Merschmeyer, M.; Meyer, A.; Millet, P.; Mukherjee, S.; Pook, T.; Radziej, M.; Reithler, H.; Rieger, M.; Scheuch, F.; Teyssier, D.; Thüer, S.; Flügge, G.; Kargoll, B.; Kress, T.; Künsken, A.; Müller, T.; Nehrkorn, A.; Nowack, A.; Pistone, C.; Pooth, O.; Stahl, A.; Aldaya Martin, M.; Arndt, T.; Asawatangtrakuldee, C.; Beernaert, K.; Behnke, O.; Behrens, U.; Bermúdez Martínez, A.; Bin Anuar, A. A.; Borras, K.; Botta, V.; Campbell, A.; Connor, P.; Contreras-Campana, C.; Costanza, F.; Danilov, V.; De Wit, A.; Diez Pardos, C.; Domínguez Damiani, D.; Eckerlin, G.; Eckstein, D.; Eichhorn, T.; Elwood, A.; Eren, E.; Gallo, E.; Garay Garcia, J.; Geiser, A.; Grados Luyando, J. M.; Grohsjean, A.; Gunnellini, P.; Guthoff, M.; Harb, A.; Hauk, J.; Jung, H.; Kasemann, M.; Keaveney, J.; Kleinwort, C.; Knolle, J.; Korol, I.; Krücker, D.; Lange, W.; Lelek, A.; Lenz, T.; Lipka, K.; Lohmann, W.; Mankel, R.; Melzer-Pellmann, I.-A.; Meyer, A. B.; Meyer, M.; Missiroli, M.; Mittag, G.; Mnich, J.; Mussgiller, A.; Pitzl, D.; Raspereza, A.; Savitskyi, M.; Saxena, P.; Shevchenko, R.; Stefaniuk, N.; Tholen, H.; Van Onsem, G. P.; Walsh, R.; Wen, Y.; Wichmann, K.; Wissing, C.; Zenaiev, O.; Aggleton, R.; Bein, S.; Blobel, V.; Centis Vignali, M.; Dreyer, T.; Garutti, E.; Gonzalez, D.; Haller, J.; Hinzmann, A.; Hoffmann, M.; Karavdina, A.; Kasieczka, G.; Klanner, R.; Kogler, R.; Kovalchuk, N.; Kurz, S.; Kutzner, V.; Lange, J.; Marconi, D.; Multhaup, J.; Niedziela, M.; Nowatschin, D.; Peiffer, T.; Perieanu, A.; Reimers, A.; Scharf, C.; Schleper, P.; Schmidt, A.; Schumann, S.; Schwandt, J.; Sonneveld, J.; Stadie, H.; Steinbrück, G.; Stober, F. M.; Stöver, M.; Troendle, D.; Usai, E.; Vanhoefer, A.; Vormwald, B.; Akbiyik, M.; Barth, C.; Baselga, M.; Baur, S.; Butz, E.; Caspart, R.; Chwalek, T.; Colombo, F.; De Boer, W.; Dierlamm, A.; Faltermann, N.; Freund, B.; Friese, R.; Giffels, M.; Harrendorf, M. A.; Hartmann, F.; Heindl, S. M.; Husemann, U.; Kassel, F.; Kudella, S.; Mildner, H.; Mozer, M. U.; Müller, Th.; Plagge, M.; Quast, G.; Rabbertz, K.; Schröder, M.; Shvetsov, I.; Sieber, G.; Simonis, H. J.; Ulrich, R.; Wayand, S.; Weber, M.; Weiler, T.; Williamson, S.; Wöhrmann, C.; Wolf, R.; Anagnostou, G.; Daskalakis, G.; Geralis, T.; Kyriakis, A.; Loukas, D.; Topsis-Giotis, I.; Karathanasis, G.; Kesisoglou, S.; Panagiotou, A.; Saoulidou, N.; Tziaferi, E.; Kousouris, K.; Papakrivopoulos, I.; Evangelou, I.; Foudas, C.; Gianneios, P.; Katsoulis, P.; Kokkas, P.; Mallios, S.; Manthos, N.; Papadopoulos, I.; Paradas, E.; Strologas, J.; Triantis, F. A.; Tsitsonis, D.; Csanad, M.; Filipovic, N.; Pasztor, G.; Surányi, O.; Veres, G. I.; Bencze, G.; Hajdu, C.; Horvath, D.; Hunyadi, Á.; Sikler, F.; Veszpremi, V.; Vesztergombi, G.; Vámi, T. Á.; Beni, N.; Czellar, S.; Karancsi, J.; Makovec, A.; Molnar, J.; Szillasi, Z.; Bartók, M.; Raics, P.; Trocsanyi, Z. L.; Ujvari, B.; Choudhury, S.; Komaragiri, J. R.; Bahinipati, S.; Mal, P.; Mandal, K.; Nayak, A.; Sahoo, D. K.; Swain, S. K.; Bansal, S.; Beri, S. B.; Bhatnagar, V.; Chauhan, S.; Chawla, R.; Dhingra, N.; Gupta, R.; Kaur, A.; Kaur, M.; Kaur, S.; Kumar, R.; Kumari, P.; Lohan, M.; Mehta, A.; Sharma, S.; Singh, J. B.; Walia, G.; Kumar, Ashok; Shah, Aashaq; Bhardwaj, A.; Choudhary, B. C.; Garg, R. B.; Keshri, S.; Kumar, A.; Malhotra, S.; Naimuddin, M.; Ranjan, K.; Sharma, R.; Bhardwaj, R.; Bhattacharya, R.; Bhattacharya, S.; Bhawandeep, U.; Bhowmik, D.; Dey, S.; Dutt, S.; Dutta, S.; Ghosh, S.; Majumdar, N.; Mondal, K.; Mukhopadhyay, S.; Nandan, S.; Purohit, A.; Rout, P. K.; Roy, A.; Roy Chowdhury, S.; Sarkar, S.; Sharan, M.; Singh, B.; Thakur, S.; Behera, P. K.; Chudasama, R.; Dutta, D.; Jha, V.; Kumar, V.; Mohanty, A. K.; Netrakanti, P. K.; Pant, L. M.; Shukla, P.; Topkar, A.; Aziz, T.; Dugad, S.; Mahakud, B.; Mitra, S.; Mohanty, G. B.; Sur, N.; Sutar, B.; Banerjee, S.; Bhattacharya, S.; Chatterjee, S.; Das, P.; Guchait, M.; Jain, Sa.; Kumar, S.; Maity, M.; Majumder, G.; Mazumdar, K.; Sahoo, N.; Sarkar, T.; Wickramage, N.; Chauhan, S.; Dube, S.; Hegde, V.; Kapoor, A.; Kothekar, K.; Pandey, S.; Rane, A.; Sharma, S.; Chenarani, S.; Eskandari Tadavani, E.; Etesami, S. M.; Khakzad, M.; Mohammadi Najafabadi, M.; Naseri, M.; Paktinat Mehdiabadi, S.; Rezaei Hosseinabadi, F.; Safarzadeh, B.; Zeinali, M.; Felcini, M.; Grunewald, M.; Abbrescia, M.; Calabria, C.; Colaleo, A.; Creanza, D.; Cristella, L.; De Filippis, N.; De Palma, M.; Di Florio, A.; Errico, F.; Fiore, L.; Gelmi, A.; Iaselli, G.; Lezki, S.; Maggi, G.; Maggi, M.; Marangelli, B.; Miniello, G.; My, S.; Nuzzo, S.; Pompili, A.; Pugliese, G.; Radogna, R.; Ranieri, A.; Selvaggi, G.; Sharma, A.; Silvestris, L.; Venditti, R.; Verwilligen, P.; Zito, G.; Abbiendi, G.; Battilana, C.; Bonacorsi, D.; Borgonovi, L.; Braibant-Giacomelli, S.; Campanini, R.; Capiluppi, P.; Castro, A.; Cavallo, F. R.; Chhibra, S. S.; Codispoti, G.; Cuffiani, M.; Dallavalle, G. M.; Fabbri, F.; Fanfani, A.; Fasanella, D.; Giacomelli, P.; Grandi, C.; Guiducci, L.; Iemmi, F.; Marcellini, S.; Masetti, G.; Montanari, A.; Navarria, F. L.; Perrotta, A.; Rossi, A. M.; Rovelli, T.; Siroli, G. P.; Tosi, N.; Albergo, S.; Costa, S.; Di Mattia, A.; Giordano, F.; Potenza, R.; Tricomi, A.; Tuve, C.; Barbagli, G.; Chatterjee, K.; Ciulli, V.; Civinini, C.; D'Alessandro, R.; Focardi, E.; Latino, G.; Lenzi, P.; Meschini, M.; Paoletti, S.; Russo, L.; Sguazzoni, G.; Strom, D.; Viliani, L.; Benussi, L.; Bianco, S.; Fabbri, F.; Piccolo, D.; Primavera, F.; Calvelli, V.; Ferro, F.; Ravera, F.; Robutti, E.; Tosi, S.; Benaglia, A.; Beschi, A.; Brianza, L.; Brivio, F.; Ciriolo, V.; Dinardo, M. E.; Fiorendi, S.; Gennai, S.; Ghezzi, A.; Govoni, P.; Malberti, M.; Malvezzi, S.; Manzoni, R. A.; Menasce, D.; Moroni, L.; Paganoni, M.; Pauwels, K.; Pedrini, D.; Pigazzini, S.; Ragazzi, S.; Tabarelli de Fatis, T.; Buontempo, S.; Cavallo, N.; Di Guida, S.; Fabozzi, F.; Fienga, F.; Galati, G.; Iorio, A. O. M.; Khan, W. A.; Lista, L.; Meola, S.; Paolucci, P.; Sciacca, C.; Thyssen, F.; Voevodina, E.; Azzi, P.; Bacchetta, N.; Benato, L.; Bisello, D.; Boletti, A.; Carlin, R.; Carvalho Antunes De Oliveira, A.; Checchia, P.; De Castro Manzano, P.; Dorigo, T.; Dosselli, U.; Gasparini, F.; Gasparini, U.; Gozzelino, A.; Lacaprara, S.; Margoni, M.; Meneguzzo, A. T.; Pozzobon, N.; Ronchese, P.; Rossin, R.; Simonetto, F.; Tiko, A.; Torassa, E.; Zanetti, M.; Zotto, P.; Zumerle, G.; Braghieri, A.; Magnani, A.; Montagna, P.; Ratti, S. P.; Re, V.; Ressegotti, M.; Riccardi, C.; Salvini, P.; Vai, I.; Vitulo, P.; Alunni Solestizi, L.; Biasini, M.; Bilei, G. M.; Cecchi, C.; Ciangottini, D.; Fanò, L.; Lariccia, P.; Leonardi, R.; Manoni, E.; Mantovani, G.; Mariani, V.; Menichelli, M.; Rossi, A.; Santocchia, A.; Spiga, D.; Androsov, K.; Azzurri, P.; Bagliesi, G.; Bianchini, L.; Boccali, T.; Borrello, L.; Castaldi, R.; Ciocci, M. A.; Dell'Orso, R.; Fedi, G.; Giannini, L.; Giassi, A.; Grippo, M. T.; Ligabue, F.; Lomtadze, T.; Manca, E.; Mandorli, G.; Messineo, A.; Palla, F.; Rizzi, A.; Spagnolo, P.; Tenchini, R.; Tonelli, G.; Venturi, A.; Verdini, P. G.; Barone, L.; Cavallari, F.; Cipriani, M.; Daci, N.; Del Re, D.; Di Marco, E.; Diemoz, M.; Gelli, S.; Longo, E.; Marzocchi, B.; Meridiani, P.; Organtini, G.; Pandolfi, F.; Paramatti, R.; Preiato, F.; Rahatlou, S.; Rovelli, C.; Santanastasio, F.; Amapane, N.; Arcidiacono, R.; Argiro, S.; Arneodo, M.; Bartosik, N.; Bellan, R.; Biino, C.; Cartiglia, N.; Castello, R.; Cenna, F.; Costa, M.; Covarelli, R.; Degano, A.; Demaria, N.; Kiani, B.; Mariotti, C.; Maselli, S.; Migliore, E.; Monaco, V.; Monteil, E.; Monteno, M.; Obertino, M. M.; Pacher, L.; Pastrone, N.; Pelliccioni, M.; Pinna Angioni, G. L.; Romero, A.; Ruspa, M.; Sacchi, R.; Shchelina, K.; Sola, V.; Solano, A.; Staiano, A.; Belforte, S.; Casarsa, M.; Cossutti, F.; Della Ricca, G.; Zanetti, A.; Kim, D. H.; Kim, G. N.; Kim, M. S.; Lee, J.; Lee, S.; Lee, S. W.; Moon, C. S.; Oh, Y. D.; Sekmen, S.; Son, D. C.; Yang, Y. C.; Kim, H.; Moon, D. H.; Oh, G.; Brochero Cifuentes, J. A.; Goh, J.; Kim, T. J.; Cho, S.; Choi, S.; Go, Y.; Gyun, D.; Ha, S.; Hong, B.; Jo, Y.; Kim, Y.; Lee, K.; Lee, K. S.; Lee, S.; Lim, J.; Park, S. K.; Roh, Y.; Almond, J.; Kim, J.; Kim, J. S.; Lee, H.; Lee, K.; Nam, K.; Oh, S. B.; Radburn-Smith, B. C.; Seo, S. h.; Yang, U. K.; Yoo, H. D.; Yu, G. B.; Kim, H.; Kim, J. H.; Lee, J. S. H.; Park, I. C.; Choi, Y.; Hwang, C.; Lee, J.; Yu, I.; Dudenas, V.; Juodagalvis, A.; Vaitkus, J.; Ahmed, I.; Ibrahim, Z. A.; Md Ali, M. A. B.; Mohamad Idris, F.; Wan Abdullah, W. A. T.; Yusli, M. N.; Zolkapli, Z.; Reyes-Almanza, R.; Ramirez-Sanchez, G.; Duran-Osuna, M. C.; Castilla-Valdez, H.; De La Cruz-Burelo, E.; Heredia-De La Cruz, I.; Rabadan-Trejo, R. I.; Lopez-Fernandez, R.; Mejia Guisao, J.; Sanchez-Hernandez, A.; Carrillo Moreno, S.; Oropeza Barrera, C.; Vazquez Valencia, F.; Eysermans, J.; Pedraza, I.; Salazar Ibarguen, H. A.; Uribe Estrada, C.; Morelos Pineda, A.; Krofcheck, D.; Butler, P. H.; Ahmad, A.; Ahmad, M.; Hassan, Q.; Hoorani, H. R.; Saddique, A.; Shah, M. A.; Shoaib, M.; Waqas, M.; Bialkowska, H.; Bluj, M.; Boimska, B.; Frueboes, T.; Górski, M.; Kazana, M.; Nawrocki, K.; Szleper, M.; Traczyk, P.; Zalewski, P.; Bunkowski, K.; Byszuk, A.; Doroba, K.; Kalinowski, A.; Konecki, M.; Krolikowski, J.; Misiura, M.; Olszewski, M.; Pyskir, A.; Walczak, M.; Bargassa, P.; Beirão Da Cruz E Silva, C.; Di Francesco, A.; Faccioli, P.; Galinhas, B.; Gallinaro, M.; Hollar, J.; Leonardo, N.; Lloret Iglesias, L.; Nemallapudi, M. 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J.; Auzinger, G.; Bainbridge, R.; Bloch, P.; Borg, J.; Breeze, S.; Buchmuller, O.; Bundock, A.; Casasso, S.; Colling, D.; Corpe, L.; Dauncey, P.; Davies, G.; Della Negra, M.; Di Maria, R.; Haddad, Y.; Hall, G.; Iles, G.; James, T.; Komm, M.; Lane, R.; Laner, C.; Lyons, L.; Magnan, A.-M.; Malik, S.; Mastrolorenzo, L.; Matsushita, T.; Nash, J.; Nikitenko, A.; Palladino, V.; Pesaresi, M.; Richards, A.; Rose, A.; Scott, E.; Seez, C.; Shtipliyski, A.; Strebler, T.; Summers, S.; Tapper, A.; Uchida, K.; Vazquez Acosta, M.; Virdee, T.; Wardle, N.; Winterbottom, D.; Wright, J.; Zenz, S. C.; Cole, J. E.; Hobson, P. R.; Khan, A.; Kyberd, P.; Morton, A.; Reid, I. D.; Teodorescu, L.; Zahid, S.; Borzou, A.; Call, K.; Dittmann, J.; Hatakeyama, K.; Liu, H.; Pastika, N.; Smith, C.; Bartek, R.; Dominguez, A.; Buccilli, A.; Cooper, S. I.; Henderson, C.; Rumerio, P.; West, C.; Arcaro, D.; Avetisyan, A.; Bose, T.; Gastler, D.; Rankin, D.; Richardson, C.; Rohlf, J.; Sulak, L.; Zou, D.; Benelli, G.; Cutts, D.; Hadley, M.; Hakala, J.; Heintz, U.; Hogan, J. M.; Kwok, K. H. M.; Laird, E.; Landsberg, G.; Lee, J.; Mao, Z.; Morrison, T.; Narain, M.; Pazzini, J.; Piperov, S.; Sagir, S.; Syarif, R.; Yu, D.; Band, R.; Brainerd, C.; Breedon, R.; Burns, D.; Calderon De La Barca Sanchez, M.; Chertok, M.; Conway, J.; Conway, R.; Cox, P. T.; Erbacher, R.; Flores, C.; Funk, G.; Ko, W.; Lander, R.; Mclean, C.; Mulhearn, M.; Pellett, D.; Pilot, J.; Shalhout, S.; Shi, M.; Smith, J.; Stolp, D.; Taylor, D.; Tos, K.; Tripathi, M.; Wang, Z.; Zhang, F.; Bachtis, M.; Bravo, C.; Cousins, R.; Dasgupta, A.; Florent, A.; Hauser, J.; Ignatenko, M.; Mccoll, N.; Regnard, S.; Saltzberg, D.; Schnaible, C.; Valuev, V.; Bouvier, E.; Burt, K.; Clare, R.; Ellison, J.; Gary, J. W.; Ghiasi Shirazi, S. M. A.; Hanson, G.; Karapostoli, G.; Kennedy, E.; Lacroix, F.; Long, O. R.; Olmedo Negrete, M.; Paneva, M. I.; Si, W.; Wang, L.; Wei, H.; Wimpenny, S.; Yates, B. R.; Branson, J. G.; Cittolin, S.; Derdzinski, M.; Gerosa, R.; Gilbert, D.; Hashemi, B.; Holzner, A.; Klein, D.; Kole, G.; Krutelyov, V.; Letts, J.; Masciovecchio, M.; Olivito, D.; Padhi, S.; Pieri, M.; Sani, M.; Sharma, V.; Simon, S.; Tadel, M.; Vartak, A.; Wasserbaech, S.; Wood, J.; Würthwein, F.; Yagil, A.; Zevi Della Porta, G.; Amin, N.; Bhandari, R.; Bradmiller-Feld, J.; Campagnari, C.; Citron, M.; Dishaw, A.; Dutta, V.; Franco Sevilla, M.; Gouskos, L.; Heller, R.; Incandela, J.; Ovcharova, A.; Qu, H.; Richman, J.; Stuart, D.; Suarez, I.; Yoo, J.; Anderson, D.; Bornheim, A.; Bunn, J.; Lawhorn, J. M.; Newman, H. B.; Nguyen, T. Q.; Pena, C.; Spiropulu, M.; Vlimant, J. R.; Wilkinson, R.; Xie, S.; Zhang, Z.; Zhu, R. Y.; Andrews, M. B.; Ferguson, T.; Mudholkar, T.; Paulini, M.; Russ, J.; Sun, M.; Vogel, H.; Vorobiev, I.; Weinberg, M.; Cumalat, J. P.; Ford, W. T.; Jensen, F.; Johnson, A.; Krohn, M.; Leontsinis, S.; MacDonald, E.; Mulholland, T.; Stenson, K.; Ulmer, K. A.; Wagner, S. R.; Alexander, J.; Chaves, J.; Cheng, Y.; Chu, J.; Datta, A.; Mcdermott, K.; Mirman, N.; Patterson, J. R.; Quach, D.; Rinkevicius, A.; Ryd, A.; Skinnari, L.; Soffi, L.; Tan, S. M.; Tao, Z.; Thom, J.; Tucker, J.; Wittich, P.; Zientek, M.; Abdullin, S.; Albrow, M.; Alyari, M.; Apollinari, G.; Apresyan, A.; Apyan, A.; Banerjee, S.; Bauerdick, L. A. T.; Beretvas, A.; Berryhill, J.; Bhat, P. C.; Bolla, G.; Burkett, K.; Butler, J. N.; Canepa, A.; Cerati, G. B.; Cheung, H. W. K.; Chlebana, F.; Cremonesi, M.; Duarte, J.; Elvira, V. D.; Freeman, J.; Gecse, Z.; Gottschalk, E.; Gray, L.; Green, D.; Grünendahl, S.; Gutsche, O.; Hanlon, J.; Harris, R. M.; Hasegawa, S.; Hirschauer, J.; Hu, Z.; Jayatilaka, B.; Jindariani, S.; Johnson, M.; Joshi, U.; Klima, B.; Kortelainen, M. J.; Kreis, B.; Lammel, S.; Lincoln, D.; Lipton, R.; Liu, M.; Liu, T.; Lopes De Sá, R.; Lykken, J.; Maeshima, K.; Magini, N.; Marraffino, J. M.; Mason, D.; McBride, P.; Merkel, P.; Mrenna, S.; Nahn, S.; O'Dell, V.; Pedro, K.; Prokofyev, O.; Rakness, G.; Ristori, L.; Savoy-Navarro, A.; Schneider, B.; Sexton-Kennedy, E.; Soha, A.; Spalding, W. J.; Spiegel, L.; Stoynev, S.; Strait, J.; Strobbe, N.; Taylor, L.; Tkaczyk, S.; Tran, N. V.; Uplegger, L.; Vaandering, E. W.; Vernieri, C.; Verzocchi, M.; Vidal, R.; Wang, M.; Weber, H. A.; Whitbeck, A.; Wu, W.; Acosta, D.; Avery, P.; Bortignon, P.; Bourilkov, D.; Brinkerhoff, A.; Carnes, A.; Carver, M.; Curry, D.; Field, R. D.; Furic, I. K.; Gleyzer, S. V.; Joshi, B. M.; Konigsberg, J.; Korytov, A.; Kotov, K.; Ma, P.; Matchev, K.; Mei, H.; Mitselmakher, G.; Shi, K.; Sperka, D.; Terentyev, N.; Thomas, L.; Wang, J.; Wang, S.; Yelton, J.; Joshi, Y. R.; Linn, S.; Markowitz, P.; Rodriguez, J. L.; Ackert, A.; Adams, T.; Askew, A.; Hagopian, S.; Hagopian, V.; Johnson, K. F.; Kolberg, T.; Martinez, G.; Perry, T.; Prosper, H.; Saha, A.; Santra, A.; Sharma, V.; Yohay, R.; Baarmand, M. M.; Bhopatkar, V.; Colafranceschi, S.; Hohlmann, M.; Noonan, D.; Roy, T.; Yumiceva, F.; Adams, M. R.; Apanasevich, L.; Berry, D.; Betts, R. R.; Cavanaugh, R.; Chen, X.; Dittmer, S.; Evdokimov, O.; Gerber, C. E.; Hangal, D. A.; Hofman, D. J.; Jung, K.; Kamin, J.; Sandoval Gonzalez, I. D.; Tonjes, M. B.; Varelas, N.; Wang, H.; Wu, Z.; Zhang, J.; Bilki, B.; Clarida, W.; Dilsiz, K.; Durgut, S.; Gandrajula, R. P.; Haytmyradov, M.; Khristenko, V.; Merlo, J.-P.; Mermerkaya, H.; Mestvirishvili, A.; Moeller, A.; Nachtman, J.; Ogul, H.; Onel, Y.; Ozok, F.; Penzo, A.; Snyder, C.; Tiras, E.; Wetzel, J.; Yi, K.; Blumenfeld, B.; Cocoros, A.; Eminizer, N.; Fehling, D.; Feng, L.; Gritsan, A. V.; Hung, W. T.; Maksimovic, P.; Roskes, J.; Sarica, U.; Swartz, M.; Xiao, M.; You, C.; Al-bataineh, A.; Baringer, P.; Bean, A.; Boren, S.; Bowen, J.; Castle, J.; Khalil, S.; Kropivnitskaya, A.; Majumder, D.; Mcbrayer, W.; Murray, M.; Rogan, C.; Royon, C.; Sanders, S.; Schmitz, E.; Tapia Takaki, J. D.; Wang, Q.; Ivanov, A.; Kaadze, K.; Maravin, Y.; Modak, A.; Mohammadi, A.; Saini, L. K.; Skhirtladze, N.; Rebassoo, F.; Wright, D.; Baden, A.; Baron, O.; Belloni, A.; Eno, S. C.; Feng, Y.; Ferraioli, C.; Hadley, N. J.; Jabeen, S.; Jeng, G. Y.; Kellogg, R. G.; Kunkle, J.; Mignerey, A. C.; Ricci-Tam, F.; Shin, Y. H.; Skuja, A.; Tonwar, S. C.; Abercrombie, D.; Allen, B.; Azzolini, V.; Barbieri, R.; Baty, A.; Bauer, G.; Bi, R.; Brandt, S.; Busza, W.; Cali, I. A.; D'Alfonso, M.; Demiragli, Z.; Gomez Ceballos, G.; Goncharov, M.; Harris, P.; Hsu, D.; Hu, M.; Iiyama, Y.; Innocenti, G. M.; Klute, M.; Kovalskyi, D.; Lee, Y.-J.; Levin, A.; Luckey, P. D.; Maier, B.; Marini, A. C.; Mcginn, C.; Mironov, C.; Narayanan, S.; Niu, X.; Paus, C.; Roland, C.; Roland, G.; Stephans, G. S. F.; Sumorok, K.; Tatar, K.; Velicanu, D.; Wang, J.; Wang, T. W.; Wyslouch, B.; Zhaozhong, S.; Benvenuti, A. C.; Chatterjee, R. M.; Evans, A.; Hansen, P.; Kalafut, S.; Kubota, Y.; Lesko, Z.; Mans, J.; Nourbakhsh, S.; Ruckstuhl, N.; Rusack, R.; Turkewitz, J.; Wadud, M. A.; Acosta, J. G.; Oliveros, S.; Avdeeva, E.; Bloom, K.; Claes, D. R.; Fangmeier, C.; Golf, F.; Gonzalez Suarez, R.; Kamalieddin, R.; Kravchenko, I.; Monroy, J.; Siado, J. E.; Snow, G. R.; Stieger, B.; Godshalk, A.; Harrington, C.; Iashvili, I.; Nguyen, D.; Parker, A.; Rappoccio, S.; Roozbahani, B.; Alverson, G.; Barberis, E.; Freer, C.; Hortiangtham, A.; Massironi, A.; Morse, D. M.; Orimoto, T.; Teixeira De Lima, R.; Wamorkar, T.; Wang, B.; Wisecarver, A.; Wood, D.; Bhattacharya, S.; Charaf, O.; Hahn, K. A.; Mucia, N.; Odell, N.; Schmitt, M. H.; Sung, K.; Trovato, M.; Velasco, M.; Bucci, R.; Dev, N.; Hildreth, M.; Hurtado Anampa, K.; Jessop, C.; Karmgard, D. J.; Kellams, N.; Lannon, K.; Li, W.; Loukas, N.; Marinelli, N.; Meng, F.; Mueller, C.; Musienko, Y.; Planer, M.; Reinsvold, A.; Ruchti, R.; Siddireddy, P.; Smith, G.; Taroni, S.; Wayne, M.; Wightman, A.; Wolf, M.; Woodard, A.; Alimena, J.; Antonelli, L.; Bylsma, B.; Durkin, L. S.; Flowers, S.; Francis, B.; Hart, A.; Hill, C.; Ji, W.; Ling, T. Y.; Luo, W.; Winer, B. L.; Wulsin, H. W.; Cooperstein, S.; Driga, O.; Elmer, P.; Hardenbrook, J.; Hebda, P.; Higginbotham, S.; Kalogeropoulos, A.; Lange, D.; Luo, J.; Marlow, D.; Mei, K.; Ojalvo, I.; Olsen, J.; Palmer, C.; Piroué, P.; Salfeld-Nebgen, J.; Stickland, D.; Tully, C.; Malik, S.; Norberg, S.; Barker, A.; Barnes, V. E.; Das, S.; Gutay, L.; Jones, M.; Jung, A. W.; Khatiwada, A.; Miller, D. H.; Neumeister, N.; Peng, C. C.; Qiu, H.; Schulte, J. F.; Sun, J.; Wang, F.; Xiao, R.; Xie, W.; Cheng, T.; Dolen, J.; Parashar, N.; Chen, Z.; Ecklund, K. M.; Freed, S.; Geurts, F. J. M.; Guilbaud, M.; Kilpatrick, M.; Li, W.; Michlin, B.; Padley, B. P.; Roberts, J.; Rorie, J.; Shi, W.; Tu, Z.; Zabel, J.; Zhang, A.; Bodek, A.; de Barbaro, P.; Demina, R.; Duh, Y. t.; Ferbel, T.; Galanti, M.; Garcia-Bellido, A.; Han, J.; Hindrichs, O.; Khukhunaishvili, A.; Lo, K. H.; Tan, P.; Verzetti, M.; Ciesielski, R.; Goulianos, K.; Mesropian, C.; Agapitos, A.; Chou, J. P.; Gershtein, Y.; Gómez Espinosa, T. A.; Halkiadakis, E.; Heindl, M.; Hughes, E.; Kaplan, S.; Kunnawalkam Elayavalli, R.; Kyriacou, S.; Lath, A.; Montalvo, R.; Nash, K.; Osherson, M.; Saka, H.; Salur, S.; Schnetzer, S.; Sheffield, D.; Somalwar, S.; Stone, R.; Thomas, S.; Thomassen, P.; Walker, M.; Delannoy, A. G.; Heideman, J.; Riley, G.; Rose, K.; Spanier, S.; Thapa, K.; Bouhali, O.; Castaneda Hernandez, A.; Celik, A.; Dalchenko, M.; De Mattia, M.; Delgado, A.; Dildick, S.; Eusebi, R.; Gilmore, J.; Huang, T.; Kamon, T.; Mueller, R.; Pakhotin, Y.; Patel, R.; Perloff, A.; Perniè, L.; Rathjens, D.; Safonov, A.; Tatarinov, A.; Akchurin, N.; Damgov, J.; De Guio, F.; Dudero, P. R.; Faulkner, J.; Gurpinar, E.; Kunori, S.; Lamichhane, K.; Lee, S. W.; Mengke, T.; Muthumuni, S.; Peltola, T.; Undleeb, S.; Volobouev, I.; Wang, Z.; Greene, S.; Gurrola, A.; Janjam, R.; Johns, W.; Maguire, C.; Melo, A.; Ni, H.; Padeken, K.; Ruiz Alvarez, J. D.; Sheldon, P.; Tuo, S.; Velkovska, J.; Xu, Q.; Arenton, M. W.; Barria, P.; Cox, B.; Hirosky, R.; Joyce, M.; Ledovskoy, A.; Li, H.; Neu, C.; Sinthuprasith, T.; Wang, Y.; Wolfe, E.; Xia, F.; Harr, R.; Karchin, P. E.; Poudyal, N.; Sturdy, J.; Thapa, P.; Zaleski, S.; Brodski, M.; Buchanan, J.; Caillol, C.; Carlsmith, D.; Dasu, S.; Dodd, L.; Duric, S.; Gomber, B.; Grothe, M.; Herndon, M.; Hervé, A.; Hussain, U.; Klabbers, P.; Lanaro, A.; Levine, A.; Long, K.; Loveless, R.; Rekovic, V.; Ruggles, T.; Savin, A.; Smith, N.; Smith, W. H.; Woods, N.; CMS Collaboration

    2018-05-01

    A search for narrow resonances decaying to bottom quark-antiquark pairs is presented, using a data sample of proton-proton collisions at √{s }=8 TeV corresponding to an integrated luminosity of 19.7 fb-1 . The search is extended to masses lower than those reached in typical searches for resonances decaying into jet pairs at the LHC, by taking advantage of triggers that identify jets originating from bottom quarks. No significant excess of events is observed above the background predictions. Limits are set on the product of cross section and branching fraction to bottom quarks for spin 0, 1, and 2 resonances in the mass range of 325-1200 GeV. These results improve on the limits for resonances decaying into jet pairs in the 325-500 GeV mass range.

  16. Pressure Fluctuation Characteristics of Narrow Gauge Train Running Through Tunnel

    NASA Astrophysics Data System (ADS)

    Suzuki, Masahiro; Sakuma, Yutaka

    Pressure fluctuations on the sides of narrow (1067 mm) gauge trains running in tunnels are measured for the first time to investigate the aerodynamic force acting on the trains. The present measurements are compared with earlier measurements obtained with the Shinkansen trains. The results are as follows: (1) The aerodynamic force, which stems from pressure fluctuations on the sides of cars, puts the energy into the vibration of the car body running through a tunnel. (2) While the pressure fluctuations appear only on one of the two sides of the trains running in double-track tunnels, the fluctuations in opposite phase on both sides in single-track tunnels. (3) The on-track test data of the narrow gauge trains show the same tendency as those of the Shinkansen trains, although it is suggested that the pressure fluctuations develop faster along the narrow gauge trains than the Shinkansen trains.

  17. Spectral filtering using active metasurfaces compatible with narrow bandgap III-V infrared detectors

    DOE PAGES

    Wolf, Omri; Campione, Salvatore; Kim, Jin; ...

    2016-01-01

    Narrow-bandgap semiconductors such as alloys of InAsAlSb and their heterostructures are considered promising candidates for next generation infrared photodetectors and devices. The prospect of actively tuning the spectral responsivity of these detectors at the pixel level is very appealing. In principle, this could be achieved with a tunable metasurface fabricated monolithically on the detector pixel. Here, we present first steps towards that goal using a complementary metasurface strongly coupled to an epsilon-near-zero (ENZ) mode operating in the long-wave region of the infrared spectrum. We fabricate such a coupled system using the same epitaxial layers used for infrared pixels in amore » focal plane array and demonstrate the existence of ENZ modes in high mobility layers of InAsSb. We confirm that the coupling strength between the ENZ mode and the metasurface depends on the ENZ layer thickness and demonstrate a transmission modulation on the order of 25%. Lastly, we further show numerically the expected tunable spectral behavior of such coupled system under reverse and forward bias, which could be used in future electrically tunable detectors.« less

  18. Narrow Scale Flow and a Weak Field by the Top of Earth's Core: Evidence from Orsted, Magsat and Secular Variation

    NASA Technical Reports Server (NTRS)

    Voorhies, Coerte V.

    2004-01-01

    As Earth's main magnetic field weakens, our magnetic shield against the onslaught of the solar wind thins. And the field strength needed to fend off battering by solar coronal mass ejections is decreasing, just when the delicate complexity of modem, vulnerable, electro-technological systems is increasing at an unprecedented rate. Recently, a working group of distinguished scientist from across the nation has asked NASA's Solid Earth and Natural Hazards program a key question: What are the dynamics of Earth s magnetic field and its interactions with the Earth system? Paleomagnetic studies of crustal rocks magnetized in the geologic past reveal that polarity reversals have occurred many times during Earth s history. Networked super-computer simulations of core field and flow, including effects of gravitational, pressure, rotational Coriolis, magnetic and viscous forces, suggest how this might happen in detail. And space-based measurements of the real, time-varying magnetic field help constrain estimates of the speed and direction of fluid iron flowing near the top of the core and enable tests of some hypotheses about such flow. Now scientists at NASA s Goddard Space Flight Center have developed and applied methods to test the hypotheses of narrow scale flow and of a dynamically weak magnetic field near the top of Earth s core. Using two completely different methods, C. V. Voorhies has shown these hypotheses lead to specific theoretical forms for the "spectrum" of Earth s main magnetic field and the spectrum of its rate of change. Much as solar physicists use a prism to separate sunlight into its spectrum, from long wavelength red to short wavelength blue light, geophysicists use a digital prism, spherical harmonic analysis, to separate the measured geomagnetic field into its spectrum, from long to short wavelength fields. They do this for the rate of change of the field as well.

  19. Narrowing the Achievement Gap: A Case Study of an Urban School

    ERIC Educational Resources Information Center

    Lugo, Rosalinda

    2010-01-01

    The goal of this case study was to identify the cultural norms, practices, and programs of an urban school that narrowed the achievement gap. The reason for identifying these factors in a successful school was to add to the body of literature regarding the achievement gap and what a struggling school was able to do to narrow the gap. This case…

  20. Formation of the UV Spectrum of Molecular Hydrogen in the Sun

    NASA Astrophysics Data System (ADS)

    Jaeggli, S. A.; Judge, P. G.; Daw, A. N.

    2018-03-01

    Ultraviolet (UV) lines of molecular hydrogen have been observed in solar spectra for almost four decades, but the behavior of the molecular spectrum and its implications for solar atmospheric structure are not fully understood. Data from the High-Resolution Telescope Spectrometer (HRTS) instrument revealed that H2 emission forms in particular regions, selectively excited by a bright UV transition region and chromospheric lines. We test the conditions under which H2 emission can originate by studying non-LTE models, sampling a broad range of temperature stratifications and radiation conditions. Stratification plays the dominant role in determining the population densities of H2, which forms in greatest abundance near the continuum photosphere. However, opacity due to the photoionization of Si and other neutrals determines the depth to which UV radiation can penetrate to excite the H2. Thus the majority of H2 emission forms in a narrow region, at about 650 km in standard one-dimensional (1D) models of the quiet Sun, near the τ = 1 opacity surface for the exciting UV radiation, generally coming from above. When irradiated from above using observed intensities of bright UV emission lines, detailed non-LTE calculations show that the spectrum of H2 seen in the quiet-Sun Solar Ultraviolet Measurement of Emitted Radiation atlas spectrum and HRTS light-bridge spectrum can be satisfactorily reproduced in 1D stratified atmospheres, without including three-dimensional or time-dependent thermal structures. A detailed comparison to observations from 1205 to 1550 Å is presented, and the success of this 1D approach to modeling solar UV H2 emission is illustrated by the identification of previously unidentified lines and upper levels in HRTS spectra.

  1. Broad-Spectrum Antibiotic Treatment and Subsequent Childhood Type 1 Diabetes: A Nationwide Danish Cohort Study.

    PubMed

    Clausen, Tine D; Bergholt, Thomas; Bouaziz, Olivier; Arpi, Magnus; Eriksson, Frank; Rasmussen, Steen; Keiding, Niels; Løkkegaard, Ellen C

    2016-01-01

    Studies link antibiotic treatment and delivery by cesarean section with increased risk of chronic diseases through changes of the gut-microbiota. We aimed to evaluate the association of broad-spectrum antibiotic treatment during the first two years of life with subsequent onset of childhood type 1 diabetes and the potential effect-modification by mode of delivery. A Danish nationwide cohort study including all singletons born during 1997-2010. End of follow-up by December 2012. Four national registers provided information on antibiotic redemptions, outcome and confounders. Redemptions of antibiotic prescriptions during the first two years of life was classified into narrow-spectrum or broad-spectrum antibiotics. Children were followed from age two to fourteen, both inclusive. The risk of type 1 diabetes with onset before the age of 15 years was assessed by Cox regression. A total of 858,201 singletons contributed 5,906,069 person-years, during which 1,503 children developed type 1 diabetes. Redemption of broad-spectrum antibiotics during the first two years of life was associated with an increased rate of type 1 diabetes during the following 13 years of life (HR 1.13; 95% CI 1.02 to 1.25), however, the rate was modified by mode of delivery. Broad-spectrum antibiotics were associated with an increased rate of type 1 diabetes in children delivered by either intrapartum cesarean section (HR 1.70; 95% CI 1.15 to 2.51) or prelabor cesarean section (HR 1.63; 95% CI 1.11 to 2.39), but not in vaginally delivered children. Number needed to harm was 433 and 562, respectively. The association with broad-spectrum antibiotics was not modified by parity, genetic predisposition or maternal redemption of antibiotics during pregnancy or lactation. Redemption of broad-spectrum antibiotics during infancy is associated with an increased risk of childhood type 1 diabetes in children delivered by cesarean section.

  2. Structure and substrate ion binding in the sodium/proton antiporter PaNhaP

    PubMed Central

    Wöhlert, David; Kühlbrandt, Werner; Yildiz, Özkan

    2014-01-01

    Sodium/proton antiporters maintain intracellular pH and sodium levels. Detailed structures of antiporters with bound substrate ions are essential for understanding how they work. We have resolved the substrate ion in the dimeric, electroneutral sodium/proton antiporter PaNhaP from Pyrococcus abyssi at 3.2 Å, and have determined its structure in two different conformations at pH 8 and pH 4. The ion is coordinated by three acidic sidechains, a water molecule, a serine and a main-chain carbonyl in the unwound stretch of trans-membrane helix 5 at the deepest point of a negatively charged cytoplasmic funnel. A second narrow polar channel may facilitate proton uptake from the cytoplasm. Transport activity of PaNhaP is cooperative at pH 6 but not at pH 5. Cooperativity is due to pH-dependent allosteric coupling of protomers through two histidines at the dimer interface. Combined with comprehensive transport studies, the structures of PaNhaP offer unique new insights into the transport mechanism of sodium/proton antiporters. DOI: http://dx.doi.org/10.7554/eLife.03579.001 PMID:25426802

  3. Meniscus-force-mediated layer transfer technique using single-crystalline silicon films with midair cavity: Application to fabrication of CMOS transistors on plastic substrates

    NASA Astrophysics Data System (ADS)

    Sakaike, Kohei; Akazawa, Muneki; Nakagawa, Akitoshi; Higashi, Seiichiro

    2015-04-01

    A novel low-temperature technique for transferring a silicon-on-insulator (SOI) layer with a midair cavity (supported by narrow SiO2 columns) by meniscus force has been proposed, and a single-crystalline Si (c-Si) film with a midair cavity formed in dog-bone shape was successfully transferred to a poly(ethylene terephthalate) (PET) substrate at its heatproof temperature or lower. By applying this proposed transfer technique, high-performance c-Si-based complementary metal-oxide-semiconductor (CMOS) transistors were successfully fabricated on the PET substrate. The key processes are the thermal oxidation and subsequent hydrogen annealing of the SOI layer on the midair cavity. These processes ensure a good MOS interface, and the SiO2 layer works as a “blocking” layer that blocks contamination from PET. The fabricated n- and p-channel c-Si thin-film transistors (TFTs) on the PET substrate showed field-effect mobilities of 568 and 103 cm2 V-1 s-1, respectively.

  4. Polished polymide substrate

    DOEpatents

    Farah, John; Sudarshanam, Venkatapuram S.

    2003-05-13

    Polymer substrates, in particular polyimide substrates, and polymer laminates for optical applications are described. Polyimide substrates are polished on one or both sides depending on their thickness, and single-layer or multi-layer waveguide structures are deposited on the polished polyimide substrates. Optical waveguide devices are machined by laser ablation using a combination of IR and UV lasers. A waveguide-fiber coupler with a laser-machined groove for retaining the fiber is also disclosed.

  5. High prevalence of narrow angles among Chinese-American glaucoma and glaucoma suspect patients.

    PubMed

    Seider, Michael I; Pekmezci, Melike; Han, Ying; Sandhu, Simi; Kwok, Shiu Y; Lee, Roland Y; Lin, Shan C

    2009-01-01

    To evaluate the prevalence of gonioscopically narrow angles in a Chinese-American population with glaucoma or glaucoma suspicion. Charts from all Chinese-American patients seen in a comprehensive ophthalmology clinic in the Chinatown district of San Francisco in 2002 were reviewed. One eye from each patient with glaucoma or glaucoma suspicion that met inclusion criteria was included (n=108). Data were collected for sex, age, race (self-declared), refraction (spherical equivalent), intraocular pressure, gonioscopy, and vertical cup-to-disk ratio. Sixty percent (n=65) of Chinese-American eyes with glaucoma or glaucoma suspicion had gonioscopically narrow angles (Shaffer grade < or = 2 in 3 or more quadrants). Those with narrow angles were significantly older (P=0.004) than their open angle counterparts, but the 2 groups did not differ in terms of sex, refraction, intraocular pressure, or cup-to-disk ratio (all, P > or = 0.071). In a multivariate model including age, sex, and refraction as predictors of angle grade (open or narrow), only age was a significant predictor of angle grade (P=0.004). A large proportion of Chinese-Americans in our study population with glaucoma or glaucoma suspicion had gonioscopically narrow angles. In multivariate analysis, patients with narrow angles were older than those with open angles but did not differ from them in terms of sex or refraction. Continued evaluation of angle closure glaucoma risk among Chinese-Americans is needed.

  6. Electromagnetic field enhancement and spectrum shaping through plasmonically integrated optical vortices.

    PubMed

    Ahn, Wonmi; Boriskina, Svetlana V; Hong, Yan; Reinhard, Björn M

    2012-01-11

    We introduce a new design approach for surface-enhanced Raman spectroscopy (SERS) substrates that is based on molding the optical powerflow through a sequence of coupled nanoscale optical vortices "pinned" to rationally designed plasmonic nanostructures, referred to as Vortex Nanogear Transmissions (VNTs). We fabricated VNTs composed of Au nanodiscs by electron beam lithography on quartz substrates and characterized their near- and far-field responses through combination of computational electromagnetism, and elastic and inelastic scattering spectroscopy. Pronounced dips in the far-field scattering spectra of VNTs provide experimental evidence for an efficient light trapping and circulation within the nanostructures. Furthermore, we demonstrate that VNT integration into periodic arrays of Au nanoparticles facilitates the generation of high E-field enhancements in the VNTs at multiple defined wavelengths. We show that spectrum shaping in nested VNT structures is achieved through an electromagnetic feed-mechanism driven by the coherent multiple scattering in the plasmonic arrays and that this process can be rationally controlled by tuning the array period. The ability to generate high E-field enhancements at predefined locations and frequencies makes nested VNTs interesting substrates for challenging SERS applications. © 2011 American Chemical Society

  7. The Gamma-Ray Emitting Radio-Loud Narrow-Line Seyfert 1 Galaxy PKS 2004-447 II. The Radio View

    NASA Technical Reports Server (NTRS)

    Schulz, R.; Kreikenbohm, A.; Kadler, M.; Ojha, R.; Ros, E.; Stevens, J.; Edwards, P. G.; Carpenter, B.; Elsaesser, D.; Gehrels, N.; hide

    2016-01-01

    Context. gamma-ray-detected radio-loud narrow-line Seyfert 1 (gamma-NLS1) galaxies constitute a small but interesting sample of the gamma-ray-loud AGN. The radio-loudest gamma-NLS1 known, PKS2004447, is located in the southern hemisphere and is monitored in the radio regime by the multiwavelength monitoring programme TANAMI. Aims. We aim for the first detailed study of the radio morphology and long-term radio spectral evolution of PKS2004447, which are essential for understanding the diversity of the radio properties of gamma-NLS1s. Methods. The TANAMI VLBI monitoring program uses the Australian Long Baseline Array (LBA) and telescopes in Antarctica, Chile, New Zealand, and South Africa to monitor the jets of radio-loud active galaxies in the southern hemisphere. Lower resolution radio flux density measurements at multiple radio frequencies over four years of observations were obtained with the Australia Telescope Compact Array (ATCA). Results. The TANAMI VLBI image at 8.4GHz shows an extended one-sided jet with a dominant compact VLBI core. Its brightness temperature is consistent with equipartition, but it is an order of magnitude below other gamma-NLS1s with the sample value varying over two orders of magnitude. We find a compact morphology with a projected large-scale size 11 kpc and a persistent steep radio spectrum with moderate flux-density variability. Conclusions. PKS2004447 appears to be a unique member of the gamma-NLS1 sample. It exhibits blazar-like features, such as a flat featureless X-ray spectrum and a core-dominated, one-sided parsec-scale jet with indications for relativistic beaming. However, the data also reveal properties atypical for blazars, such as a radio spectrum and large-scale size consistent with compact-steep-spectrum (CSS) objects, which are usually associated with young radio sources. These characteristics are unique among all gamma-NLS1s and extremely rare among gamma-ray-loud AGN.

  8. Broad Anatomical Variation within a Narrow Wood Density Range--A Study of Twig Wood across 69 Australian Angiosperms.

    PubMed

    Ziemińska, Kasia; Westoby, Mark; Wright, Ian J

    2015-01-01

    Just as people with the same weight can have different body builds, woods with the same wood density can have different anatomies. Here, our aim was to assess the magnitude of anatomical variation within a restricted range of wood density and explore its potential ecological implications. Twig wood of 69 angiosperm tree and shrub species was analyzed. Species were selected so that wood density varied within a relatively narrow range (0.38-0.62 g cm-3). Anatomical traits quantified included wood tissue fractions (fibres, axial parenchyma, ray parenchyma, vessels, and conduits with maximum lumen diameter below 15 μm), vessel properties, and pith area. To search for potential ecological correlates of anatomical variation the species were sampled across rainfall and temperature contrasts, and several other ecologically-relevant traits were measured (plant height, leaf area to sapwood area ratio, and modulus of elasticity). Despite the limited range in wood density, substantial anatomical variation was observed. Total parenchyma fraction varied from 0.12 to 0.66 and fibre fraction from 0.20 to 0.74, and these two traits were strongly inversely correlated (r = -0.86, P < 0.001). Parenchyma was weakly (0.24 ≤|r|≤ 0.35, P < 0.05) or not associated with vessel properties nor with height, leaf area to sapwood area ratio, and modulus of elasticity (0.24 ≤|r|≤ 0.41, P < 0.05). However, vessel traits were fairly well correlated with height and leaf area to sapwood area ratio (0.47 ≤|r|≤ 0.65, all P < 0.001). Modulus of elasticity was mainly driven by fibre wall plus vessel wall fraction rather than by the parenchyma component. Overall, there seem to be at least three axes of variation in xylem, substantially independent of each other: a wood density spectrum, a fibre-parenchyma spectrum, and a vessel area spectrum. The fibre-parenchyma spectrum does not yet have any clear or convincing ecological interpretation.

  9. Broad Anatomical Variation within a Narrow Wood Density Range—A Study of Twig Wood across 69 Australian Angiosperms

    PubMed Central

    Ziemińska, Kasia; Westoby, Mark; Wright, Ian J.

    2015-01-01

    Objectives Just as people with the same weight can have different body builds, woods with the same wood density can have different anatomies. Here, our aim was to assess the magnitude of anatomical variation within a restricted range of wood density and explore its potential ecological implications. Methods Twig wood of 69 angiosperm tree and shrub species was analyzed. Species were selected so that wood density varied within a relatively narrow range (0.38–0.62 g cm-3). Anatomical traits quantified included wood tissue fractions (fibres, axial parenchyma, ray parenchyma, vessels, and conduits with maximum lumen diameter below 15 μm), vessel properties, and pith area. To search for potential ecological correlates of anatomical variation the species were sampled across rainfall and temperature contrasts, and several other ecologically-relevant traits were measured (plant height, leaf area to sapwood area ratio, and modulus of elasticity). Results Despite the limited range in wood density, substantial anatomical variation was observed. Total parenchyma fraction varied from 0.12 to 0.66 and fibre fraction from 0.20 to 0.74, and these two traits were strongly inversely correlated (r = -0.86, P < 0.001). Parenchyma was weakly (0.24 ≤|r|≤ 0.35, P < 0.05) or not associated with vessel properties nor with height, leaf area to sapwood area ratio, and modulus of elasticity (0.24 ≤|r|≤ 0.41, P < 0.05). However, vessel traits were fairly well correlated with height and leaf area to sapwood area ratio (0.47 ≤|r|≤ 0.65, all P < 0.001). Modulus of elasticity was mainly driven by fibre wall plus vessel wall fraction rather than by the parenchyma component. Conclusions Overall, there seem to be at least three axes of variation in xylem, substantially independent of each other: a wood density spectrum, a fibre-parenchyma spectrum, and a vessel area spectrum. The fibre-parenchyma spectrum does not yet have any clear or convincing ecological interpretation. PMID

  10. Investigating powerful jets in radio-loud narrow-line Seyfert 1s

    DOE PAGES

    Orienti, M.; D'Ammando, F.; Larsson, J.; ...

    2015-09-14

    Here, we report results on multiband observations from radio to γ-rays of the two radio-loud narrow-line Seyfert 1 (NLSy1) galaxies PKS 2004-447 and J1548+3511. Furthermore, both sources show a core–jet structure on parsec scale, while they are unresolved at the arcsecond scale. The high core dominance and the high variability brightness temperature make these NLSy1 galaxies good γ-ray source candidates. Fermi-Large Area Telescope detected γ-ray emission only from PKS 2004-447, with a γ-ray luminosity comparable to that observed in blazars. There was no γ-ray emission observed for J1548+3511. Both sources are variable in X-rays. J1548+3511 shows a hardening of themore » spectrum during high activity states, while PKS 2004-447 has no spectral variability. A spectral steepening likely related to the soft excess is hinted below 2 keV for J1548+3511, while the X-ray spectra of PKS 2004-447 collected by XMM–Newton in 2012 are described by a single power law without significant soft excess. No additional absorption above the Galactic column density or the presence of an Fe line is detected in the X-ray spectra of both sources.« less

  11. Keeping the Edges Sharp I: Honing the Theory of Narrow Rings

    NASA Astrophysics Data System (ADS)

    Hamilton, Douglas P.; Rimlinger, Thomas; Hahn, Joseph M.

    2016-05-01

    Most of the rings that encircle Saturn, Uranus, and Neptune are very narrow structures with typical radial widths of just a few kilometers. Such extreme sharpness is surprising, as even slightly different orbital periods should allow ring particles to continually jostle one another in collisions that preserve angular momentum whileinexorably draining energy. Sharp edges should blur as rings spread in response to collisions and yet they do not. The generally accepted solution to this dilemma is to bracket each narrow ring with a pair of shepherding satellites that can pump energy back into the ring to replace that lost by collisions. But only a disappointing two of roughly twenty narrow rings actually have known attendant satellites. We present a compelling alternative in which the slight eccentricities and inclinations of narrow ringlets act as internal energy sources that can be tapped to prevent ring spreading. When unattended circular rings dissipate energy they must spread radially in order to preserve angular momentum. By contrast, eccentric or inclined rings have an extra degree of freedom that can be exploited to prevent radial spreading; energy is dissipated while keeping z-component of angular momentum, sqrt(a(1-e^2))cos(i), constant by simply decreasing the overall eccentricity (e) and/or inclination (i) of the entire ring. A real narrow ring moves inward as a unit, circularizes, and drops into the equatorial plane in a process that deters radial spreading for millions or billions of years. Using secular theory with dissipation (Zhang et al. 2013), we show that narrow rings are secular eigenstates in which ellipses are nested with pericenters almost, but not exactly aligned. The misalignment of pericenters is crucial in allowing energy dissipation to be shared evenly across the ring. We predict ring surface densities that are roughly constant across the ring's width, in contrast to profiles expected for shepherded rings. Rimlinger et al. (this meeting

  12. Structural and optical properties of copper-coated substrates for solar thermal absorbers

    NASA Astrophysics Data System (ADS)

    Pratesi, Stefano; De Lucia, Maurizio; Meucci, Marco; Sani, Elisa

    2016-10-01

    Spectral selectivity, i.e. merging a high absorbance at sunlight wavelengths to a low emittance at the wavelengths of thermal spectrum, is a key characteristics for materials to be used for solar thermal receivers. It is known that spectrally selective absorbers can raise the receiver efficiency for all solar thermal technologies. Tubular sunlight receivers for parabolic trough collector (PTC) systems can be improved by the use of spectrally selective coatings. Their absorbance is increased by deposing black films, while the thermal emittance is minimized by the use of properly-prepared substrates. In this work we describe the intermediate step in the fabrication of black-chrome coated solar absorbers, namely the fabrication and characterization of copper coatings on previously nickel-plated stainless steel substrates. We investigate the copper surface features and optical properties, correlating them to the coating thickness and to the deposition process, in the perspective to assess optimal conditions for solar absorber applications.

  13. General method to evaluate substrate surface modification techniques for light extraction enhancement of organic light emitting diodes

    NASA Astrophysics Data System (ADS)

    Krummacher, B. C.; Mathai, M. K.; Choong, V.; Choulis, S. A.; So, F.; Winnacker, A.

    2006-09-01

    The external light output of organic light emitting diodes (OLEDs) can be increased by modifying the light emitting surface. The apparent light extraction enhancement is given by the ratio between the efficiency of the unmodified device and the efficiency of the modified device. This apparent light extraction enhancement is dependent on the OLED architecture itself and is not the correct value to judge the effectiveness of a technique to enhance light outcoupling due to substrate surface modification. We propose a general method to evaluate substrate surface modification techniques for light extraction enhancement of OLEDs independent from the device architecture. This method is experimentally demonstrated using green electrophosphorescent OLEDs with different device architectures. The substrate surface of these OLEDs was modified by applying a prismatic film to increase light outcoupling from the device stack. It was demonstrated that the conventionally measured apparent light extraction enhancement by means of the prismatic film does not reflect the actual performance of the light outcoupling technique. Rather, by comparing the light extracted out of the prismatic film to that generated in the OLED layers and coupled into the substrate (before the substrate/air interface), a more accurate evaluation of light outcoupling enhancement can be achieved. Furthermore we show that substrate surface modification can change the output spectrum of a broad band emitting OLED.

  14. Dynamics of Preferential Substrate Recognition in HIV-1 Protease: Redefining the Substrate Envelope

    PubMed Central

    Özen, Ayşegül; Haliloğlu, Türkan; Schiffer, Celia A.

    2011-01-01

    HIV-1 protease (PR) permits viral maturation by processing the Gag and Gag-Pro-Pol polyproteins. Though HIV-1 PR inhibitors (PIs) are used in combination antiviral therapy, the emergence of drug resistance has limited their efficacy. The rapid evolution of HIV-1 necessitates the consideration of drug resistance in novel drug-design strategies. Drug-resistant HIV-1 PR variants, while no longer efficiently inhibited, continue to efficiently hydrolyze the natural viral substrates. Though highly diverse in sequence, the HIV-1 PR substrates bind in a conserved three-dimensional shape we defined as the “substrate envelope”. We previously showed that resistance mutations arise where PIs protrude beyond the substrate envelope, as these regions are crucial for drug binding but not for substrate recognition. Here, we extend this model by considering the role of protein dynamics in the interaction of HIV-1 PR with its substrates. Seven molecular dynamics simulations of PR-substrate complexes were performed to estimate the conformational flexibility of substrates in their complexes. Interdependency of the substrate-protease interactions may compensate for the variations in cleavage-site sequences, and explain how a diverse set of sequences can be recognized as substrates by the same enzyme. This diversity may be essential for regulating sequential processing of substrates. We also define a dynamic substrate envelope as a more accurate representation of PR-substrate interactions. This dynamic substrate envelope, described by a probability distribution function, is a powerful tool for drug design efforts targeting ensembles of resistant HIV-1 PR variants with the aim of developing drugs that are less susceptible to resistance. PMID:21762811

  15. Bio-inspired in situ growth of monolayer silver nanoparticles on graphene oxide paper as multifunctional substrate

    NASA Astrophysics Data System (ADS)

    Li, Shi-Kuo; Yan, You-Xian; Wang, Jin-Long; Yu, Shu-Hong

    2013-11-01

    In this study, we report a facile bio-inspired method for large-scale preparation of highly dispersed Ag nanoparticles (NPs) on the surface of flexible reduced graphene oxide (rGO) paper with using dopamine (DA) both as a reductant and a surface modifier. Through the self-polymerization of dopamine, free-standing GO paper can be simultaneously reduced and modified with following in situ growth of monolayer Ag NPs on such a substrate. The spherical Ag NPs with an average diameter of 80 nm have a narrow size distribution and tunable cover density. Such a flexible rGO/Ag hybrid paper presents enhanced antibacterial activity against E. coli and a high active and sensitive SERS response toward Rhodamine 6G (R6G) molecules. The detection signals can be obtained while the R6G concentration is as low as to 10-8 M. This work provides a simple strategy for large-scale fabrication of monolayer Ag NPs on flexible rGO paper as a portable antibacterial substrate and a potential SERS substrate for molecular detection applications.In this study, we report a facile bio-inspired method for large-scale preparation of highly dispersed Ag nanoparticles (NPs) on the surface of flexible reduced graphene oxide (rGO) paper with using dopamine (DA) both as a reductant and a surface modifier. Through the self-polymerization of dopamine, free-standing GO paper can be simultaneously reduced and modified with following in situ growth of monolayer Ag NPs on such a substrate. The spherical Ag NPs with an average diameter of 80 nm have a narrow size distribution and tunable cover density. Such a flexible rGO/Ag hybrid paper presents enhanced antibacterial activity against E. coli and a high active and sensitive SERS response toward Rhodamine 6G (R6G) molecules. The detection signals can be obtained while the R6G concentration is as low as to 10-8 M. This work provides a simple strategy for large-scale fabrication of monolayer Ag NPs on flexible rGO paper as a portable antibacterial substrate and a

  16. Application of narrow-band television to industrial and commercial communications

    NASA Technical Reports Server (NTRS)

    Embrey, B. C., Jr.; Southworth, G. R.

    1974-01-01

    The development of narrow-band systems for use in space systems is presented. Applications of the technology to future spacecraft requirements are discussed along with narrow-band television's influence in stimulating development within the industry. The transferral of the technology into industrial and commercial communications is described. Major areas included are: (1) medicine; (2) education; (3) remote sensing for traffic control; and (5) weather observation. Applications in data processing, image enhancement, and information retrieval are provided by the combination of the TV camera and the computer.

  17. Numerical Study on Outflows in Seyfert Galaxies I: Narrow Line Region Outflows in NGC 4151

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mou, Guobin; Wang, Tinggui; Yang, Chenwei, E-mail: gbmou@ustc.edu.cn

    The origin of narrow line region (NLR) outflows remains unknown. In this paper, we explore the scenario in which these outflows are circumnuclear clouds driven by energetic accretion disk winds. We choose the well-studied nearby Seyfert galaxy NGC 4151 as an example. By performing 3D hydrodynamical simulations, we are able to reproduce the radial distributions of velocity, mass outflow rate, and kinetic luminosity of NLR outflows in the inner 100 pc deduced from spatial resolved spectroscopic observations. The demanded kinetic luminosity of disk winds is about two orders of magnitude higher than that inferred from the NLR outflows, but ismore » close to the ultrafast outflows (UFO) detected in the X-ray spectrum and a few times lower than the bolometric luminosity of the Seyfert. Our simulations imply that the scenario is viable for NGC 4151. The existence of the underlying disk winds can be confirmed by their impacts on higher density ISM, e.g., shock excitation signs, and the pressure in NLR.« less

  18. Narrow Energy Gap between Triplet and Singlet Excited States of Sn2+ in Borate Glass

    PubMed Central

    Masai, Hirokazu; Yamada, Yasuhiro; Suzuki, Yuto; Teramura, Kentaro; Kanemitsu, Yoshihiko; Yoko, Toshinobu

    2013-01-01

    Transparent inorganic luminescent materials have attracted considerable scientific and industrial attention recently because of their high chemical durability and formability. However, photoluminescence dynamics of ns2-type ions in oxide glasses has not been well examined, even though they can exhibit high quantum efficiency. We report on the emission property of Sn2+-doped strontium borate glasses. Photoluminescence dynamics studies show that the peak energy of the emission spectrum changes with time because of site distribution of emission centre in glass. It is also found that the emission decay of the present glass consists of two processes: a faster S1-S0 transition and a slower T1-S0 relaxation, and also that the energy difference between T1 and S1 states was found to be much smaller than that of (Sn, Sr)B6O10 crystals. We emphasize that the narrow energy gap between the S1 and T1 states provides the glass phosphor a high quantum efficiency, comparable to commercial crystalline phosphors. PMID:24345869

  19. X-ray structures of the Pseudomonas cichorii D-tagatose 3-epimerase mutant form C66S recognizing deoxy sugars as substrates.

    PubMed

    Yoshida, Hiromi; Yoshihara, Akihide; Ishii, Tomohiko; Izumori, Ken; Kamitori, Shigehiro

    2016-12-01

    Pseudomonas cichorii D-tagatose 3-epimerase (PcDTE), which has a broad substrate specificity, efficiently catalyzes the epimerization of not only D-tagatose to D-sorbose but also D-fructose to D-psicose (D-allulose) and also recognizes the deoxy sugars as substrates. In an attempt to elucidate the substrate recognition and catalytic reaction mechanisms of PcDTE for deoxy sugars, the X-ray structures of the PcDTE mutant form with the replacement of Cys66 by Ser (PcDTE_C66S) in complexes with deoxy sugars were determined. These X-ray structures showed that substrate recognition by the enzyme at the 1-, 2-, and 3-positions is responsible for enzymatic activity and that substrate-enzyme interactions at the 4-, 5-, and 6-positions are not essential for the catalytic reaction of the enzyme leading to the broad substrate specificity of PcDTE. They also showed that the epimerization site of 1-deoxy 3-keto D-galactitol is shifted from C3 to C4 and that 1-deoxy sugars may bind to the catalytic site in the inhibitor-binding mode. The hydrophobic groove that acts as an accessible surface for substrate binding is formed through the dimerization of PcDTE. In PcDTE_C66S/deoxy sugar complex structures, bound ligand molecules in both the linear and ring forms were detected in the hydrophobic groove, while bound ligand molecules in the catalytic site were in the linear form. This result suggests that the sugar-ring opening of a substrate may occur in the hydrophobic groove and also that the narrow channel of the passageway to the catalytic site allows a substrate in the linear form to pass through.

  20. Method of forming fluorine-bearing diamond layer on substrates, including tool substrates

    DOEpatents

    Chang, R. P. H.; Grannen, Kevin J.

    2002-01-01

    A method of forming a fluorine-bearing diamond layer on non-diamond substrates, especially on tool substrates comprising a metal matrix and hard particles, such as tungsten carbide particles, in the metal matrix. The substrate and a fluorine-bearing plasma or other gas are then contacted under temperature and pressure conditions effective to nucleate fluorine-bearing diamond on the substrate. A tool insert substrate is treated prior to the diamond nucleation and growth operation by etching both the metal matrix and the hard particles using suitable etchants.

  1. The executive prominent/memory prominent spectrum in Alzheimer’s disease is highly heritable

    PubMed Central

    Mez, Jesse; Mukherjee, Shubhabrata; Thornton, Timothy; Fardo, David W.; Trittschuh, Emily; Sutti, Sheila; Sherva, Richard; Kauwe, John S.; Naj, Adam C.; Beecham, Gary W.; Gross, Alden; Saykin, Andrew J.; Green, Robert C.; Crane, Paul K.

    2016-01-01

    Late-onset Alzheimer’s disease (LOAD) can present heterogeneously, with several subtypes recognized, including dysexecutive AD. One way to identify people with dysexecutive AD is to consider the difference between memory and executive functioning, which we refer to as the executive prominent/memory prominent spectrum. We aimed to determine if this spectrum was heritable. We used neuropsychological and genetic data from people with mild LOAD (Clinical Dementia Rating 0.5 or 1.0) from the National Alzheimer’s Coordinating Center and the Alzheimer’s Disease Neuroimaging Initiative. We cocalibrated the neuropsychological data to obtain executive functioning and memory scores and used their difference as a continuous phenotype to calculate its heritability overall and by chromosome. Narrow-sense heritability of the difference between memory and executive functioning scores was 0.68 (standard error 0.12). Single nucleotide polymorphisms on chromosomes 1, 2, 4, 11, 12, and 18 explained the largest fraction of phenotypic variance, with signals from each chromosome accounting for 5%–7%. The chromosomal pattern of heritability differed substantially from that of LOAD itself. PMID:27103524

  2. The X-Ray Time Variability and Spectrum of Gamma-Cassiopeiae X:0053+604

    NASA Astrophysics Data System (ADS)

    Parmar, A. N.; Israel, G. L.; Stella, L.; White, N. E.

    1993-08-01

    A 30 h duration EXOSAT observation made in 1985 December is used to examine the X-ray time variability and spectrum of the Be star γ Cassiopeiae (X 0053+604). We find that the X-ray lightcurve is dominated by irregular energy-independent flaring on time-scales ≳ 100 s. This flaring markedly decreases the sensitivity to any periodic signals. We find no evidence for the 6000 5 oscillations reported by Frontera et al. (1987) from an earlier EXOSAT observation. We suggest that these arise from statistical fluctuations in the red noise power. The X-ray spectrum of γ Cas can either be modeled by thermal emission from an optically thin plasma with a temperature of 12 keV, or by a cut-off power-law model with a narrow iron line at an energy of 6.67 keV. The origin of the X-ray emission in this system remains open since its spectral and temporal properties are consistent with both an acereting neutron star and a white dwarf while its high temperature argues against a coronal mechanism.

  3. Narrow-band filters for the lightning imager

    NASA Astrophysics Data System (ADS)

    Piegari, Angela; Di Sarcina, Ilaria; Grilli, Maria Luisa; Menchini, Francesca; Scaglione, Salvatore; Sytchkova, Anna; Zola, Danilo; Cuevas, Leticia P.

    2017-11-01

    The study of lightning phenomena will be carried out by a dedicated instrument, the lightning imager, that will make use of narrow-band transmission filters for separating the Oxygen emission lines in the clouds, from the background signal. The design, manufacturing and testing of these optical filters will be described here.

  4. Wet-chemical passivation of atomically flat and structured silicon substrates for solar cell application

    NASA Astrophysics Data System (ADS)

    Angermann, H.; Rappich, J.; Korte, L.; Sieber, I.; Conrad, E.; Schmidt, M.; Hübener, K.; Polte, J.; Hauschild, J.

    2008-04-01

    Special sequences of wet-chemical oxidation and etching steps were optimised with respect to the etching behaviour of differently oriented silicon to prepare very smooth silicon interfaces with excellent electronic properties on mono- and poly-crystalline substrates. Surface photovoltage (SPV) and photoluminescence (PL) measurements, atomic force microscopy (AFM) and scanning electron microscopy (SEM) investigations were utilised to develop wet-chemical smoothing procedures for atomically flat and structured surfaces, respectively. Hydrogen-termination as well as passivation by wet-chemical oxides were used to inhibit surface contamination and native oxidation during the technological processing. Compared to conventional pre-treatments, significantly lower micro-roughness and densities of surface states were achieved on mono-crystalline Si(100), on evenly distributed atomic steps, such as on vicinal Si(111), on silicon wafers with randomly distributed upside pyramids, and on poly-crystalline EFG ( Edge-defined Film-fed- Growth) silicon substrates. The recombination loss at a-Si:H/c-Si interfaces prepared on c-Si substrates with randomly distributed upside pyramids was markedly reduced by an optimised wet-chemical smoothing procedure, as determined by PL measurements. For amorphous-crystalline hetero-junction solar cells (ZnO/a-Si:H(n)/c-Si(p)/Al) with textured c-Si substrates the smoothening procedure results in a significant increase of short circuit current Isc, fill factor and efficiency η. The scatter in the cell parameters for measurements on different cells is much narrower, as compared to conventional pre-treatments, indicating more well-defined and reproducible surface conditions prior to a-Si:H emitter deposition and/or a higher stability of the c-Si surface against variations in the a-Si:H deposition conditions.

  5. Determinants of lens vault and association with narrow angles in patients from Singapore.

    PubMed

    Tan, Gavin S; He, Mingguang; Zhao, Wanting; Sakata, Lisandro M; Li, Jialiang; Nongpiur, Monisha E; Lavanya, Raghavan; Friedman, David S; Aung, Tin

    2012-07-01

    To describe the distribution and determinants of lens vault and to investigate the association of lens vault with narrow angles. Prospective cross-sectional study. Phakic subjects 50 years and older were evaluated at a primary healthcare clinic with gonioscopy, partial laser interferometry, and anterior segment optical coherence tomography (AS-OCT). Narrow angles were defined as posterior trabecular meshwork not visible for ≥2 quadrants on non-indentation gonioscopy. Lens vault was defined as the perpendicular distance between the anterior pole of the crystalline lens and the horizontal line joining the 2 scleral spurs on horizontal AS-OCT scans. Analysis of covariance, multivariate logistic regression, and area under the receiver operating characteristic curves (AUC) were performed. Of the 2047 subjects recruited, 582 were excluded because of poor image quality or inability to locate scleral spurs, leaving 1465 subjects for analysis. Eyes with narrow angles had greater lens vault compared to eyes with open angles (775.6 µm vs 386.5 µm, P < .0001). Women had significantly greater lens vault than men (497.28 µm vs 438.56 µm, P < .001), and lens vault increased significantly with age (P for trend <.001). Adjusted for age and sex, significant associations with greater lens vault were shorter axial length, shallower anterior chamber depth(ACD), higher intraocular pressure, and more hyperopic spherical equivalent (all P < .001). On multivariate analysis, subjects with lens vault >667.6 µm were more likely to have narrow angles (OR 2.201, 95% CI: 1.070-4.526) compared to those with lens vault ≤462.7 µm. The AUC for lens vault (0.816) and ACD (0.822) for detecting narrow angles were similar (P = .582). Lens vault was independently associated with narrow angles and may be useful in screening to detect eyes with narrow angles. Copyright © 2012 Elsevier Inc. All rights reserved.

  6. Phylogenetic and Functional Substrate Specificity for Endolithic Microbial Communities in Hyper-Arid Environments

    PubMed Central

    Crits-Christoph, Alexander; Robinson, Courtney K.; Ma, Bing; Ravel, Jacques; Wierzchos, Jacek; Ascaso, Carmen; Artieda, Octavio; Souza-Egipsy, Virginia; Casero, M. Cristina; DiRuggiero, Jocelyne

    2016-01-01

    Under extreme water deficit, endolithic (inside rock) microbial ecosystems are considered environmental refuges for life in cold and hot deserts, yet their diversity and functional adaptations remain vastly unexplored. The metagenomic analyses of the communities from two rock substrates, calcite and ignimbrite, revealed that they were dominated by Cyanobacteria, Actinobacteria, and Chloroflexi. The relative distribution of major phyla was significantly different between the two substrates and biodiversity estimates, from 16S rRNA gene sequences and from the metagenomic data, all pointed to a higher taxonomic diversity in the calcite community. While both endolithic communities showed adaptations to extreme aridity and to the rock habitat, their functional capabilities revealed significant differences. ABC transporters and pathways for osmoregulation were more diverse in the calcite chasmoendolithic community. In contrast, the ignimbrite cryptoendolithic community was enriched in pathways for secondary metabolites, such as non-ribosomal peptides (NRP) and polyketides (PK). Assemblies of the metagenome data produced population genomes for the major phyla found in both communities and revealed a greater diversity of Cyanobacteria population genomes for the calcite substrate. Draft genomes of the dominant Cyanobacteria in each community were constructed with more than 93% estimated completeness. The two annotated proteomes shared 64% amino acid identity and a significantly higher number of genes involved in iron update, and NRPS gene clusters, were found in the draft genomes from the ignimbrite. Both the community-wide and genome-specific differences may be related to higher water availability and the colonization of large fissures and cracks in the calcite in contrast to a harsh competition for colonization space and nutrient resources in the narrow pores of the ignimbrite. Together, these results indicated that the habitable architecture of both lithic substrates

  7. High Prevalence of Narrow Angles among Chinese-American Glaucoma and Glaucoma Suspect Patients

    PubMed Central

    Seider, Michael I; Pekmezci, Melike; Han, Ying; Sandhu, Simi; Kwok, Shiu Y; Lee, Roland Y; Lin, Shan C

    2009-01-01

    Purpose To evaluate the prevalence of gonioscopically narrow angles in a Chinese-American population with glaucoma or glaucoma suspicion. Patients and Methods Charts from all Chinese-American patients seen in a comprehensive ophthalmology clinic in the Chinatown district of San Francisco in 2002 were reviewed. One eye from each patient with glaucoma or glaucoma suspicion that met inclusion criteria was included (n=108). Data was collected for gender, age, race (self-declared), refraction (spherical equivalent), intraocular pressure (IOP), gonioscopy and vertical cup-to-disk ratio (CDR). Results Sixty percent (n=65) of Chinese-American eyes with glaucoma or glaucoma suspicion had gonioscopically narrow angles (Shaffer grade ≤2 in three or more quadrants). Those with narrow angles were significantly older (P=0.004) than their open angle counterparts, but the two groups did not differ in terms of gender, refraction, IOP or CDR (all, P≥0.071). In a multivariate model including age, gender and refraction as predictors of angle grade (open or narrow), only age was a significant predictor of angle grade (P=0.004). Conclusions A large proportion of Chinese-Americans in our study population with glaucoma or glaucoma suspicion had gonioscopically narrow angles. In multivariate analysis, patients with narrow angles were older than those with open angles but did not differ from them in terms of gender or refraction. Continued evaluation of angle closure glaucoma risk among Chinese-Americans is needed. PMID:19826385

  8. A new nitrilase-producing strain named Rhodobacter sphaeroides LHS-305: biocatalytic characterization and substrate specificity.

    PubMed

    Yang, Chunsheng; Wang, Xuedong; Wei, Dongzhi

    2011-12-01

    The characteristics of the new nitrilase-producing strain Rhodobacter sphaeroides LHS-305 were investigated. By investigating several parameters influencing nitrilase production, the specific cell activity was ultimately increased from 24.5 to 75.0 μmol g(-1) min(-1), and hereinto, the choice of inducer proved the most important factor. The aromatic nitriles (such as 3-cyanopyridine and benzonitrile) were found to be the most favorable substrates of the nitrilase by analyzing the substrate spectrum. It was speculated that the unsaturated carbon atom attached to the cyano group was crucial for this type of nitrilase. The value of apparent K (m), substrate inhibition constant, and product inhibition constant of the nitrilase against 3-cyanopyridine were 4.5 × 10(-2), 29.2, and 8.6 × 10(-3) mol L(-1), respectively. When applied in nicotinic acid preparation, the nitrilase is able to hydrolyze 200 mmol L(-1) 3-cyanopyridine with 93% conversion rate in 13 h by 6.1 g L(-1) cells (dry cell weight).

  9. Why Hart found narrow ecospheres--a minor science mystery solved.

    PubMed

    Levenson, Barton Paul

    2015-05-01

    To explain why two NASA computer simulation studies in the 1970s (Hart, 1978 , 1979 ) briefly rocked the subfield of astrobiology and SETI studies by showing very narrow habitable zones (HZs) for solar-type stars. Although other studies later supported wider HZs, it was never clear why the Hart simulations found the narrow limits they did. Investigation of the state of climate studies and radiative transfer models in the period 1960-1970 provides a likely explanation. Hart's findings were in line with earlier results, preventing him from noticing that his radiation model was inadequate.

  10. INTERNATIONAL CONFERENCE ON SEMICONDUCTOR INJECTION LASERS SELCO-87: Influence of spontaneous fluctuations on the emission spectrum of an injection semiconductor laser

    NASA Astrophysics Data System (ADS)

    Gulyaev, Yurii V.; Suris, Robert A.; Tager, A. A.; Élenkrig, B. B.

    1988-11-01

    A theoretical investigation is made of fluctuation-induced excitation of side longitudinal modes in the emission spectra of semiconductor lasers, including those with an external mirror. It is shown that nonlinear refraction of light in the active region of a semiconductor laser may result in a noise redistribution of the radiation between longitudinal resonator modes and can be responsible for the multimode nature of the average emission spectrum. An analysis is made of the influence of selectivity of an external mirror on the stability of cw operation, minimum line width, and mode composition of the emission spectra of semiconductor lasers. The conditions for maximum narrowing of the emission spectrum of a semiconductor laser with an external selective mirror are identified.

  11. Substrate system for spray forming

    DOEpatents

    Chu, Men G.; Chernicoff, William P.

    2000-01-01

    A substrate system for receiving a deposit of sprayed metal droplets including a movable outer substrate on which the sprayed metal droplets are deposited. The substrate system also includes an inner substrate disposed adjacent the outer substrate where the sprayed metal droplets are deposited on the outer substrate. The inner substrate includes zones of differing thermal conductivity to resist substrate layer porosity and to resist formation of large grains and coarse constituent particles in a bulk layer of the metal droplets which have accumulated on the outer substrate. A spray forming apparatus and associated method of spray forming a molten metal to form a metal product using the substrate system of the invention is also provided.

  12. Substrate system for spray forming

    DOEpatents

    Chu, Men G.; Chernicoff, William P.

    2002-01-01

    A substrate system for receiving a deposit of sprayed metal droplets including a movable outer substrate on which the sprayed metal droplets are deposited. The substrate system also includes an inner substrate disposed adjacent the outer substrate where the sprayed metal droplets are deposited on the outer substrate. The inner substrate includes zones of differing thermal conductivity to resist substrate layer porosity and to resist formation of large grains and coarse constituent particles in a bulk layer of the metal droplets which have accumulated on the outer substrate. A spray forming apparatus and associated method of spray forming a molten metal to form a metal product using the substrate system of the invention is also provided.

  13. Coated substrates and process

    DOEpatents

    Chu, Wei-kan; Childs, Charles B.

    1991-01-01

    Disclosed herein is a coated substrate and a process for forming films on substrates and for providing a particularly smooth film on a substrate. The method of this invention involves subjecting a surface of a substrate to contact with a stream of ions of an inert gas having sufficient force and energy to substantially change the surface characteristics of said substrate, and then exposing a film-forming material to a stream of ions of an inert gas having sufficient energy to vaporize the atoms of said film-forming material and to transmit the vaporized atoms to the substrate surface with sufficient force to form a film bonded to the substrate. This process is particularly useful commercially because it forms strong bonds at room temperature. This invention is particularly useful for adhering a gold film to diamond and forming ohmic electrodes on diamond, but also can be used to bond other films to substrates.

  14. Narrow band imaging combined with water immersion technique in the diagnosis of celiac disease.

    PubMed

    Valitutti, Francesco; Oliva, Salvatore; Iorfida, Donatella; Aloi, Marina; Gatti, Silvia; Trovato, Chiara Maria; Montuori, Monica; Tiberti, Antonio; Cucchiara, Salvatore; Di Nardo, Giovanni

    2014-12-01

    The "multiple-biopsy" approach both in duodenum and bulb is the best strategy to confirm the diagnosis of celiac disease; however, this increases the invasiveness of the procedure itself and is time-consuming. To evaluate the diagnostic yield of a single biopsy guided by narrow-band imaging combined with water immersion technique in paediatric patients. Prospective assessment of the diagnostic accuracy of narrow-band imaging/water immersion technique-driven biopsy approach versus standard protocol in suspected celiac disease. The experimental approach correctly diagnosed 35/40 children with celiac disease, with an overall diagnostic sensitivity of 87.5% (95% CI: 77.3-97.7). An altered pattern of narrow-band imaging/water immersion technique endoscopic visualization was significantly associated with villous atrophy at guided biopsy (Spearman Rho 0.637, p<0.001). Concordance of narrow-band imaging/water immersion technique endoscopic assessments was high between two operators (K: 0.884). The experimental protocol was highly timesaving compared to the standard protocol. An altered narrow-band imaging/water immersion technique pattern coupled with high anti-transglutaminase antibodies could allow a single guided biopsy to diagnose celiac disease. When no altered mucosal pattern is visible even by narrow-band imaging/water immersion technique, multiple bulbar and duodenal biopsies should be obtained. Copyright © 2014. Published by Elsevier Ltd.

  15. Linear variable narrow bandpass optical filters in the far infrared (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Rahmlow, Thomas D.

    2017-06-01

    We are currently developing linear variable filters (LVF) with very high wavelength gradients. In the visible, these filters have a wavelength gradient of 50 to 100 nm/mm. In the infrared, the wavelength gradient covers the range of 500 to 900 microns/mm. Filter designs include band pass, long pass and ulta-high performance anti-reflection coatings. The active area of the filters is on the order of 5 to 30 mm along the wavelength gradient and up to 30 mm in the orthogonal, constant wavelength direction. Variation in performance along the constant direction is less than 1%. Repeatable performance from filter to filter, absolute placement of the filter relative to a substrate fiducial and, high in-band transmission across the full spectral band is demonstrated. Applications include order sorting filters, direct replacement of the spectrometer and hyper-spectral imaging. Off-band rejection with an optical density of greater than 3 allows use of the filter as an order sorting filter. The linear variable order sorting filters replaces other filter types such as block filters. The disadvantage of block filters is the loss of pixels due to the transition between filter blocks. The LVF is a continuous gradient without a discrete transition between filter wavelength regions. If the LVF is designed as a narrow band pass filter, it can be used in place of a spectrometer thus reducing overall sensor weight and cost while improving the robustness of the sensor. By controlling the orthogonal performance (smile) the LVF can be sized to the dimensions of the detector. When imaging on to a 2 dimensional array and operating the sensor in a push broom configuration, the LVF spectrometer performs as a hyper-spectral imager. This paper presents performance of LVF fabricated in the far infrared on substrates sized to available detectors. The impact of spot size, F-number and filter characterization are presented. Results are also compared to extended visible LVF filters.

  16. Looking through an adolescent literacy lens at the narrow view of reading.

    PubMed

    Ehren, Barbara J

    2009-04-01

    This commentary is a personal reaction to A. G. Kamhi's (2007) article on the "narrow view" of reading and his suggestion that this view be adopted as a way to address the reading problems of children and adolescents. In this article, I consider the narrow view of reading from an adolescent literacy perspective and discuss the practical implications of adopting this view in the schools. Discussion revolves around the complexities of reading comprehension, comprehension as a teachable set of complex processes, and the speech-language pathologist's role in reading comprehension. Although I acknowledge that the narrow view of reading may have merit, I opine that it may create more problems than it solves.

  17. Substrate quality alters microbial mineralization of added substrate and soil organic carbon

    NASA Astrophysics Data System (ADS)

    Jagadamma, S.; Mayes, M. A.; Steinweg, J. M.; Schaeffer, S. M.

    2014-03-01

    The rate and extent of decomposition of soil organic carbon (SOC) is dependent on substrate chemistry and microbial dynamics. Our objectives were to understand the influence of substrate chemistry on microbial processing of carbon (C), and to use model fitting to quantify differences in pool sizes and mineralization rates. We conducted an incubation experiment for 270 days using four uniformly-labeled 14C substrates (glucose, starch, cinnamic acid and stearic acid) on four different soils (a temperate Mollisol, a tropical Ultisol, a sub-arctic Andisol, and an arctic Gelisol). The 14C labeling enabled us to separate CO2 respired from added substrates and from native SOC. Microbial gene copy numbers were quantified at days 4, 30 and 270 using quantitative polymerase chain reaction (qPCR). Substrate C respiration was always higher for glucose than other substrates. Soils with cinnamic and stearic acid lost more native SOC than glucose- and starch-amended soils, despite an initial delay in respiration. Cinnamic and stearic acid amendments also exhibited higher fungal gene copy numbers at the end of incubation compared to unamended soils. We found that 270 days was sufficient to model decomposition of simple substrates (glucose and starch) with three pools, but was insufficient for more complex substrates (cinnamic and stearic acid) and native SOC. This study reveals that substrate quality imparts considerable control on microbial decomposition of newly added and native SOC, and demonstrates the need for multi-year incubation experiments to constrain decomposition parameters for the most recalcitrant fractions of SOC and added substrates.

  18. Densification behavior of ceramic and crystallizable glass materials constrained on a rigid substrate

    NASA Astrophysics Data System (ADS)

    Calata, Jesus N.

    2005-11-01

    Constrained sintering is an important process for many applications. The sintering process almost always involves some form of constraint, both internal and external, such as rigid particles, reinforcing fibers and substrates to which the porous body adheres. The densification behavior of zinc oxide and cordierite-base crystallizable glass constrained on a rigid substrate was studied to add to the understanding of the behavior of various materials undergoing sintering when subjected to external substrate constraint. Porous ZnO films were isothermally sintered at temperatures between 900°C and 1050°C. The results showed that the densification of films constrained on substrates is severely reduced. This was evident in the sintered microstructures where the particles are joined together by narrower necks forming a more open structure, instead of the equiaxed grains with wide grain boundaries observed in the freestanding films. The calculated activation energies of densification were also different. For the density range of 60 to 64%, the constrained film had an activation energy of 391 +/- 34 kJ/mole compared to 242 +/- 21 kJ/mole for the freestanding film, indicating a change in the densification mechanism. In-plane stresses were observed during the sintering of the constrained films. Yielding of the films, in which the stresses dropped slight or remained unchanged, occurred at relative densities below 60% before the stresses climbed linearly with increasing density followed by a gradual relaxation. A substantial amount of the stresses remained after cooling. Free and constrained films of the cordierite-base crystallizable glass (glass-ceramic) were sintered between 900°C and 1000°C. The substrate constraint did not have a significant effect on the densification rate but the constrained films eventually underwent expansion. Calculations of the densification activation energy showed that, on average, it was close to 1077 kJ/mole, the activation energy of the glass

  19. Optical cross-talk and surface characterization of SERS nanoimaging bundle substrates

    NASA Astrophysics Data System (ADS)

    Kiser, John B.; Cullum, Brian M.

    2010-04-01

    Due to the narrow vibrational bandwidths and unique molecular fingerprints, Raman spectroscopy can be an information rich transduction technique for chemical imaging. Dynamic systems are often difficult to measure using spontaneous Raman due to the relatively weak scattering cross-sections. Using a Raman enhancement mechanism such as surface enhanced Raman scattering (SERS), exposure times can be reduced to a reasonable level for dynamic imaging, due to the increased Raman signal intensity. This paper will discuss the development of a novel SERS substrate, fabricated on the tips of fiber-optic imaging bundles, which can be integrated into a multispectral imaging system for non-scanning chemical imaging. These substrates are fabricated by mechanically tapering a polished fiber optic imaging bundle consisting of 30,000 individual elements; producing 100-nm or smaller diameter core elements on the distal tip. Chemical etching with hydrofluoric acid creates uniform cladding spikes onto which a SERS active metal is vacuum deposited, forming the SERS active surface. By varying the size of the silver islands deposited on the cladding peaks active, surface plasmons can be tuned to various excitation frequencies. The surface of these tapered fiber optic probes will be evaluated by analysis of the SERS signal, location and shape of the active surface plasmons. The cross talk between the fiber elements will also be evaluated.

  20. Cervical spinal canal narrowing in idiopathic syringomyelia.

    PubMed

    Struck, Aaron F; Carr, Carrie M; Shah, Vinil; Hesselink, John R; Haughton, Victor M

    2016-08-01

    The cervical spine in Chiari I patient with syringomyelia has significantly different anteroposterior diameters than it does in Chiari I patients without syringomyelia. We tested the hypothesis that patients with idiopathic syringomyelia (IS) also have abnormal cervical spinal canal diameters. The finding in both groups may relate to the pathogenesis of syringomyelia. Local institutional review boards approved this retrospective study. Patients with IS were compared to age-matched controls with normal sagittal spine MR. All subjects had T1-weighted spin-echo (500/20) and T2-weighted fast spin-echo (2000/90) sagittal cervical spine images at 1.5 T. Readers blinded to demographic data and study hypothesis measured anteroposterior diameters at each cervical level. The spinal canal diameters were compared with a Mann-Whitney U test. The overall difference was assessed with a Friedman test. Seventeen subjects were read by two reviewers to assess inter-rater reliability. Fifty IS patients with 50 age-matched controls were studied. IS subjects had one or more syrinxes varying from 1 to 19 spinal segments. Spinal canal diameters narrowed from C1 to C3 and then enlarged from C5 to C7 in both groups. Diameters from C2 to C4 were narrower in the IS group (p < 0.005) than in controls. The ratio of the C3 to the C7 diameters was also smaller (p = 0.004) in IS than controls. Collectively, the spinal canal diameters in the IS were significantly different from controls (Friedman test p < 0.0001). Patients with IS have abnormally narrow upper and mid cervical spinal canal diameters and greater positive tapering between C3 and C7.

  1. Trends in broad-spectrum antibiotic prescribing for children with acute otitis media in the United States, 1998–2004

    PubMed Central

    Coco, Andrew S; Horst, Michael A; Gambler, Angela S

    2009-01-01

    Background Overuse of broad-spectrum antibiotics is associated with antibiotic resistance. Acute otitis media (AOM) is responsible for a large proportion of antibiotics prescribed for US children. Rates of broad-spectrum antibiotic prescribing for AOM are unknown. Methods Analysis of the National Ambulatory Medical Care Survey and National Hospital Ambulatory Medical Care Survey, 1998 to 2004 (N = 6,878). Setting is office-based physicians, hospital outpatient departments, and emergency departments. Patients are children aged 12 years and younger prescribed antibiotics for acute otitis media. Main outcome measure is percentage of broad-spectrum antibiotics, defined as amoxicillin/clavulanate, macrolides, cephalosporins and quinolones. Results Broad-spectrum prescribing for acute otitis media increased from 34% of visits in 1998 to 45% of visits in 2004 (P < .001 for trend). The trend was primarily attributable to an increase in prescribing of amoxicillin/clavulanate (8% to 15%; P < .001 for trend) and macrolides (9% to 15%; P < .001 for trend). Prescribing remained stable for amoxicillin and cephalosporins while decreasing for narrow-spectrum agents (12% to 3%; P < .001 for trend) over the study period. Independent predictors of broad-spectrum antibiotic prescribing were ear pain, non-white race, public and other insurance (compared to private), hospital outpatient department setting, emergency department setting, and West region (compared to South and Midwest regions), each of which was associated with lower rates of broad-spectrum prescribing. Age and fever were not associated with prescribing choice. Conclusion Prescribing of broad-spectrum antibiotics for acute otitis media has steadily increased from 1998 to 2004. Associations with non-clinical factors suggest potential for improvement in prescribing practice. PMID:19552819

  2. High Interfacial Barriers at Narrow Carbon Nanotube-Water Interfaces.

    PubMed

    Varanasi, Srinivasa Rao; Subramanian, Yashonath; Bhatia, Suresh K

    2018-06-26

    Water displays anomalous fast diffusion in narrow carbon nanotubes (CNTs), a behavior that has been reproduced in both experimental and simulation studies. However, little is reported on the effect of bulk water-CNT interfaces, which is critical to exploiting the fast transport of water across narrow carbon nanotubes in actual applications. Using molecular dynamics simulations, we investigate here the effect of such interfaces on the transport of water across arm-chair CNTs of different diameters. Our results demonstrate that diffusion of water is significantly retarded in narrow CNTs due to bulk regions near the pore entrance. The slowdown of dynamics can be attributed to the presence of large energy barriers at bulk water-CNT interfaces. The presence of such intense barriers at the bulk-CNT interface arises due to the entropy contrast between the bulk and confined regions, with water molecules undergoing high translational and rotational entropy gain on entering from the bulk to the CNT interior. The intensity of such energy barriers decreases with increase in CNT diameter. These results are very important for emerging technological applications of CNTs and other nanoscale materials, such as in nanofluidics, water purification, nanofiltration, and desalination, as well as for biological transport processes.

  3. High prevalence of narrow angles among Filipino-American patients.

    PubMed

    Seider, Michael I; Sáles, Christopher S; Lee, Roland Y; Agadzi, Anthony K; Porco, Travis C; Weinreb, Robert N; Lin, Shan C

    2011-03-01

    To determine the prevalence of gonioscopically narrow anterior chamber angles in a Filipino-American clinic population. The records of 122 consecutive, new, self-declared Filipino-American patients examined in a comprehensive ophthalmology clinic in Vallejo, California were reviewed retrospectively. After exclusion, 222 eyes from 112 patients remained for analysis. Data were collected for anterior chamber angle grade as determined by gonioscopy (Shaffer system), age, sex, manifest refraction (spherical equivalent), intraocular pressure, and cup-to-disk ratio. Data from both eyes of patients were included and modeled using standard linear mixed-effects regression. As a comparison, data were also collected from a group of 30 consecutive White patients from the same clinic. After exclusion, 50 eyes from 25 White patients remained for comparison. At least 1 eye of 24% of Filipino-American patients had a narrow anterior chamber angle (Shaffer grade ≤ 2). Filipino-American angle grade significantly decreased with increasingly hyperopic refraction (P=0.007) and larger cup-to-disk ratio (P=0.038). Filipino-American women had significantly decreased angle grades compared with men (P=0.028), but angle grade did not vary by intraocular pressure or age (all, P≥ 0.059). Narrow anterior chamber angles are highly prevalent in Filipino-American patients in our clinic population.

  4. The Radio-Loud Narrow-Line Quasar SDSS J172206.03+565451.6

    NASA Astrophysics Data System (ADS)

    Komossa, Stefanie; Voges, Wolfgang; Adorf, Hans-Martin; Xu, Dawei; Mathur, Smita; Anderson, Scott F.

    2006-03-01

    We report identification of the radio-loud narrow-line quasar SDSS J172206.03+565451.6, which we found in the course of a search for radio-loud narrow-line active galactic nuclei (AGNs). SDSS J172206.03+565451.6 is only about the fourth securely identified radio-loud narrow-line quasar and the second-most radio loud, with a radio index R1.4~100-700. Its black hole mass, MBH~=(2-3)×107 Msolar estimated from Hβ line width and 5100 Å luminosity, is unusually small given its radio loudness, and the combination of mass and radio index puts SDSS J172206.03+565451.6 in a scarcely populated region of MBH-R diagrams. SDSS J172206.03+565451.6 is a classical narrow-line Seyfert 1-type object with FWHMHβ~=1490 km s-1, an intensity ratio of [O III]/Hβ~=0.7, and Fe II emission complexes with Fe II λ4570/Hβ~=0.7. The ionization parameter of its narrow-line region, estimated from the line ratio [O II]/[O III], is similar to Seyferts, and its high ratio of [Ne V]/[Ne III] indicates a strong EUV-to-soft X-ray excess. We advertise the combined usage of [O II]/[O III] and [Ne V]/[Ne III] diagrams as a useful diagnostic tool to estimate ionization parameters and to constrain the EUV-soft X-ray continuum shape relatively independently from other parameters.

  5. High rate DC-reactive sputter deposition of Y 2O 3 film on the textured metal substrate for the superconducting coated conductor

    NASA Astrophysics Data System (ADS)

    Kim, Ho-Sup; Park, Chan; Ko, Rock-Kil; Shi, Dongqui; Chung, Jun-Ki; Ha, Hong-Soo; Park, Yu-Mi; Song, Kyu-Jeong; Youm, Do-Jun

    2005-10-01

    Y2O3 film was directly deposited on Ni-3at%W substrate by DC reactive sputtering. DC reactive sputtering was carried out using metallic Y target and water vapor for oxidizing the elements of metallic target on the substrate. The detailed conditions of DC reactive sputtering for depositions of Y2O3 films were investigated. The window of water vapor for proper growth of Y2O3 films was determined by sufficient oxidations of the Y2O3 films and the non-oxidation of the target surface, which was required for high rate sputtering. The window turned out to be fairly wide in the chamber used. As the sputtering power was raised, the deposition rate increased without narrowing the window. The fabricated Y2O3 films showed good texture qualities and surface morphologies. The YBCO film deposited directly on the Y2O3 buffered Ni-3at%W substrate showed Tc, Ic (77 K, self field), and Jc (77 K, self field) of 89 K, 64 A/cm and 1.1 MA/cm2, respectively.

  6. PREFACE: Cell-substrate interactions Cell-substrate interactions

    NASA Astrophysics Data System (ADS)

    Gardel, Margaret; Schwarz, Ulrich

    2010-05-01

    One of the most striking achievements of evolution is the ability to build cellular systems that are both robust and dynamic. Taken by themselves, both properties are obvious requirements: robustness reflects the fact that cells are there to survive, and dynamics is required to adapt to changing environments. However, it is by no means trivial to understand how these two requirements can be implemented simultaneously in a physical system. The long and difficult quest to build adaptive materials is testimony to the inherent difficulty of this goal. Here materials science can learn a lot from nature, because cellular systems show that robustness and dynamics can be achieved in a synergetic fashion. For example, the capabilities of tissues to repair and regenerate are still unsurpassed in the world of synthetic materials. One of the most important aspects of the way biological cells adapt to their environment is their adhesive interaction with the substrate. Numerous aspects of the physiology of metazoan cells, including survival, proliferation, differentiation and migration, require the formation of adhesions to the cell substrate, typically an extracellular matrix protein. Adhesions guide these diverse processes both by mediating force transmission from the cell to the substrate and by controlling biochemical signaling pathways. While the study of cell-substrate adhesions is a mature field in cell biology, a quantitative biophysical understanding of how the interactions of the individual molecular components give rise to the rich dynamics and mechanical behaviors observed for cell-substrate adhesions has started to emerge only over the last decade or so. The recent growth of research activities on cell-substrate interactions was strongly driven by the introduction of new physical techniques for surface engineering into traditional cell biological work with cell culture. For example, microcontact printing of adhesive patterns was used to show that cell fate depends

  7. Narrow beam neutron dosimetry.

    PubMed

    Ferenci, M Sutton

    2004-01-01

    Organ and effective doses have been estimated for male and female anthropomorphic mathematical models exposed to monoenergetic narrow beams of neutrons with energies from 10(-11) to 1000 MeV. Calculations were performed for anterior-posterior, posterior-anterior, left-lateral and right-lateral irradiation geometries. The beam diameter used in the calculations was 7.62 cm and the phantoms were irradiated at a height of 1 m above the ground. This geometry was chosen to simulate an accidental scenario (a worker walking through the beam) at Flight Path 30 Left (FP30L) of the Weapons Neutron Research (WNR) Facility at Los Alamos National Laboratory. The calculations were carried out using the Monte Carlo transport code MCNPX 2.5c.

  8. Dynamic film thickness between bubbles and wall in a narrow channel

    NASA Astrophysics Data System (ADS)

    Ito, Daisuke; Damsohn, Manuel; Prasser, Horst-Michael; Aritomi, Masanori

    2011-09-01

    The present paper describes a novel technique to characterize the behavior of the liquid film between gas bubbles and the wall in a narrow channel. The method is based on the electrical conductance. Two liquid film sensors are installed on both opposite walls in a narrow rectangular channel. The liquid film thickness underneath the gas bubbles is recorded by the first sensor, while the void fraction information is obtained by measuring the conductance between the pair of opposite sensors. Both measurements are taken on a large two-dimensional domain and with a high speed. This makes it possible to obtain the two-dimensional distribution of the dynamic liquid film between the bubbles and the wall. In this study, this method was applied to an air-water flow ranging from bubbly to churn regimes in the narrow channel with a gap width of 1.5 mm.

  9. Shape and size engineered cellulosic nanomaterials as broad spectrum anti-microbial compounds.

    PubMed

    Sharma, Priyanka R; Kamble, Sunil; Sarkar, Dhiman; Anand, Amitesh; Varma, Anjani J

    2016-06-01

    Oxidized celluloses have been used for decades as antimicrobial wound gauzes and surgical cotton. We now report the successful synthesis of a next generation narrow size range (25-35nm) spherical shaped nanoparticles of 2,3,6-tricarboxycellulose based on cellulose I structural features, for applications as new antimicrobial materials. This study adds to our previous study of 6-carboxycellulose. A wide range of bacteria such as Escherichia coli, Staphloccocus aureus, Bacillus subtilis and Mycobacterium tuberculosis (non-pathogenic as well as pathogenic strains) were affected by these polymers in in vitro studies. Activity against Mycobacteria were noted at high concentrations (MIC99 values 250-1000μg/ml, as compared to anti-TB drug Isoniazid 0.3μg/ml). However, the broad spectrum activity of oxidized celluloses and their nanoparticles against a wide range of bacteria, including Mycobacteria, show that these materials are promising new biocompatible and biodegradable drug delivery vehicles wherein they can play the dual role of being a drug encapsulant as well as a broad spectrum anti-microbial and anti-TB drug. Copyright © 2016. Published by Elsevier B.V.

  10. Method for shaping and aiming narrow beams. [sonar mapping and target identification

    NASA Technical Reports Server (NTRS)

    Heyser, R. C. (Inventor)

    1981-01-01

    A sonar method and apparatus is discribed which utilizes a linear frequency chirp in a transmitter/receiver having a correlator to synthesize a narrow beamwidth pattern from otherwise broadbeam transducers when there is relative velocity between the transmitter/receiver and the target. The chirp is so produced in a generator in bandwidth, B, and time, T, as to produce a time bandwidth product, TB, that is increased for a narrower angle. A replica of the chirp produced in a generator is time delayed and Doppler shifted for use as a reference in the receiver for correlation of received chirps from targets. This reference is Doppler shifted to select targets preferentially, thereby to not only synthesize a narrow beam but also aim the beam in azimuth and elevation.

  11. A Clinical Translation of the Article Titled "Evidence for the Implementation of the Early Start Denver Model for Young Children With Autism Spectrum Disorder".

    PubMed

    Shannon, Robin Adair

    2015-01-01

    The purpose of this article is to offer a clinical translation of a literature review titled "Evidence for the Implementation of the Early Start Denver Model for Young Children With Autism Spectrum Disorder" by Ryberg (2015). The literature review was conducted to determine the strength of the research evidence regarding the effectiveness of the Early Start Denver Model in improving cognitive, language, and behavioral functioning of children with autism spectrum disorder. In an effort to narrow the gap between evidence and practice, this clinical translation will discuss the components of the literature review in terms of its rationale for and objectives, methods, results, and implications for evidence-based nursing practice. © The Author(s) 2015.

  12. Broad-spectrum neodymium-doped laser glasses for high-energy chirped-pulse amplification.

    PubMed

    Hays, Greg R; Gaul, Erhard W; Martinez, Mikael D; Ditmire, Todd

    2007-07-20

    We have investigated two novel laser glasses in an effort to generate high-energy, broad-spectrum pulses from a chirped-pulse amplification Nd:glass laser. Both glasses have significantly broader spectra (>38 nm FWHM) than currently available Nd:phosphate and Nd:silicate glasses. We present calculations for small signal pulse amplification to simulate spectral gain narrowing. The technique of spectral shaping using mixed-glass architecture with an optical parametric chirped-pulse amplification front end is evaluated. Our modeling shows that amplified pulses with energies exceeding 10 kJ with sufficient bandwidth to achieve 120 fs pulsewidths are achievable with the use of the new laser glasses. With further development of current technologies, a laser system could be scaled to generate one exawatt in peak power.

  13. An Acrobatic Substrate Metamorphosis Reveals a Requirement for Substrate Conformational Dynamics in Trypsin Proteolysis*

    PubMed Central

    Kayode, Olumide; Wang, Ruiying; Pendlebury, Devon F.; Cohen, Itay; Henin, Rachel D.; Hockla, Alexandra; Soares, Alexei S.; Papo, Niv; Caulfield, Thomas R.; Radisky, Evette S.

    2016-01-01

    The molecular basis of enzyme catalytic power and specificity derives from dynamic interactions between enzyme and substrate during catalysis. Although considerable effort has been devoted to understanding how conformational dynamics within enzymes affect catalysis, the role of conformational dynamics within protein substrates has not been addressed. Here, we examine the importance of substrate dynamics in the cleavage of Kunitz-bovine pancreatic trypsin inhibitor protease inhibitors by mesotrypsin, finding that the varied conformational dynamics of structurally similar substrates can profoundly impact the rate of catalysis. A 1.4-Å crystal structure of a mesotrypsin-product complex formed with a rapidly cleaved substrate reveals a dramatic conformational change in the substrate upon proteolysis. By using long all-atom molecular dynamics simulations of acyl-enzyme intermediates with proteolysis rates spanning 3 orders of magnitude, we identify global and local dynamic features of substrates on the nanosecond-microsecond time scale that correlate with enzymatic rates and explain differential susceptibility to proteolysis. By integrating multiple enhanced sampling methods for molecular dynamics, we model a viable conformational pathway between substrate-like and product-like states, linking substrate dynamics on the nanosecond-microsecond time scale with large collective substrate motions on the much slower time scale of catalysis. Our findings implicate substrate flexibility as a critical determinant of catalysis. PMID:27810896

  14. Laccase versus Laccase-Like Multi-Copper Oxidase: A Comparative Study of Similar Enzymes with Diverse Substrate Spectra

    PubMed Central

    Reiss, Renate; Ihssen, Julian; Richter, Michael; Eichhorn, Eric; Schilling, Boris; Thöny-Meyer, Linda

    2013-01-01

    Laccases (EC 1.10.3.2) are multi-copper oxidases that catalyse the one-electron oxidation of a broad range of compounds including substituted phenols, arylamines and aromatic thiols to the corresponding radicals. Owing to their broad substrate range, copper-containing laccases are versatile biocatalysts, capable of oxidizing numerous natural and non-natural industry-relevant compounds, with water as the sole by-product. In the present study, 10 of the 11 multi-copper oxidases, hitherto considered to be laccases, from fungi, plant and bacterial origin were compared. A substrate screen of 91 natural and non-natural compounds was recorded and revealed a fairly broad but distinctive substrate spectrum amongst the enzymes. Even though the enzymes share conserved active site residues we found that the substrate ranges of the individual enzymes varied considerably. The EC classification is based on the type of chemical reaction performed and the actual name of the enzyme often refers to the physiological substrate. However, for the enzymes studied in this work such classification is not feasible, even more so as their prime substrates or natural functions are mainly unknown. The classification of multi-copper oxidases assigned as laccases remains a challenge. For the sake of simplicity we propose to introduce the term “laccase-like multi-copper oxidase” (LMCO) in addition to the term laccase that we use exclusively for the enzyme originally identified from the sap of the lacquer tree Rhus vernicifera. PMID:23755261

  15. An Extreme, Blueshifted Iron Line in the Narrow Line Seyfert 1 PG 1402+261

    NASA Technical Reports Server (NTRS)

    Reeves, J. N.; Porquet, D.; Turner, T. J.

    2004-01-01

    We report on a short, XMM-Newton observation of the radio-quiet Narrow Line Seyfert 1 PG 1402+261. The EPIC X-ray spectrum of PG 1402+261 shows a strong excess of counts between 6 - 9 keV in the rest frame. This feature can be modeled by an unusually strong (equivalent width 2 keV) and very broad energy at 7.3 keV appears blue-shifted with respect to the iron Kalpha emission band between 6.4 - 6.97 keV, whilst the blue-wing of the line extends to 9 keV in the quasar rest frame. The line profile can be fitted by reflection from the inner accretion disk, but an inclination angle of greater than 60 degrees is required to model the extreme blue-wing of the line. Furthermore the extreme strength of the line requires a geometry whereby the hard X-ray emission from PG1402+261 above 2 keV is dominated by the pure-reflection component from the disk, whilst little or none of the direct hard power-law is observed. Alternatively the spectrum above 2 keV may instead be explained by an ionized absorber, if the column density is sufficiently high (NH greater than 3 x 10(exp 23) per square centimeter) and if the matter is ionized enough to produce a deep (tau approximately equal to 1) iron K-shell absorption edge at 9 keV. This absorber could originate in a large column density, high velocity outflow, perhaps similar to those which appear to be observed in several other high accretion rate AGN. Further observations, especially at higher spectral resolution, are required to distinguish between the accretion disk reflection or outflow scenarios.

  16. Enhanced tunable narrow-band THz emission from laser-modulated electron beams

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Xiang, D.; Stupakov, G.; /SLAC

    2009-06-19

    We propose and analyze a scheme to generate enhanced narrow-band terahertz (THz) radiation through down-conversion of the frequency of optical lasers using laser-modulated electron beams. In the scheme the electron beam is first energy modulated by two lasers with wave numbers k{sub 1} and k2, respectively. After passing through a dispersion section, the energy modulation is converted to density modulation. Due to the nonlinear conversion process, the beam will have density modulation at wave number k = nk{sub 1} + mk{sub 2}, where n and m are positive or negative integers. By properly choosing the parameters for the lasers andmore » dispersion section, one can generate density modulation at THz frequency in the beam using optical lasers. This density-modulated beam can be used to generate powerful narrow-band THz radiation. Since the THz radiation is in tight synchronization with the lasers, it should provide a high temporal resolution for the optical-pump THz-probe experiments. The central frequency of the THz radiation can be easily tuned by varying the wavelength of the two lasers and the energy chirp of the electron beam. The proposed scheme is in principle able to generate intense narrow-band THz radiation covering the whole THz range and offers a promising way towards the tunable intense narrow-band THz sources.« less

  17. Radiographic screen-film noise power spectrum: variation with microdensitometer slit length.

    PubMed

    Sandrik, J M; Wagner, R F

    1981-08-15

    When the noise power spectrum (NPS) of a radiographic screen-film system is measured by microdensito-metrically scanning the film with a long narrow slit, sufficient slit length allows estimation of a section of the 2-D NPS from the 1-D film scans; insufficient length causes underestimation of the NPS, particularly at low frequencies ( greater, similar1 cycle/mm). Spectra of Hi-Plus, Par Speed, and Detail screens used with XRP films measured as a function of microdensitometer slit length tended to plateau at long slit lengths. The slit length was considered sufficient when NPS components at 0.4 cycle/mm were within 5% of the plateau. This occurred for slit lengths of at least 4.2, 2.6, and 2.5 mm for Hi-Plus, Par Speed, and Detail systems, respectively.

  18. The Radio to Gamma-ray SED of the Narrow-line Seyfert 1 1H0323+342

    NASA Astrophysics Data System (ADS)

    Ward, M.

    2017-10-01

    A sub-set of radio-loud narrow line Seyfert 1s, have been detected in gamma-rays by the Fermi Gamma-Ray satellite. Their gamma-ray emission is thought to arise from a relativistic jet. We have obtained new near-infrared spectra and used the profiles of the Paschen lines to estimate the mass of the black hole. Combining this with results from optical lines and X-ray timing analysis we arrive at a value of 2 x 10**E7 solar masses. From modelling the broad-band SED, we drive an Eddington ratio of 0.5, rising to 1.0 for a spinning black hole (a=0.8). Furthermore, we constrain the external photon field, and use a single-zone leptonic jet model to obtain a range of jet-parameters which are consistent with Compton up-scattering to produce the observed gamma-ray spectrum. This low-redshift very well studied AGN can potentially provide a useful laboratory to further our understanding of the jet/disc connection in extragalactic sources.

  19. Volume holographic lens spectrum-splitting photovoltaic system for high energy yield with direct and diffuse solar illumination

    NASA Astrophysics Data System (ADS)

    Chrysler, Benjamin D.; Wu, Yuechen; Yu, Zhengshan; Kostuk, Raymond K.

    2017-08-01

    In this paper a prototype spectrum-splitting photovoltaic system based on volume holographic lenses (VHL) is designed, fabricated and tested. In spectrum-splitting systems, incident sunlight is divided in spectral bands for optimal conversion by a set of single-junction PV cells that are laterally separated. The VHL spectrumsplitting system in this paper has a form factor similar to conventional silicon PV modules but with higher efficiencies (>30%). Unlike many other spectrum-splitting systems that have been proposed in the past, the system in this work converts both direct and diffuse sunlight while using inexpensive 1-axis tracking systems. The VHL system uses holographic lenses that focus light at a transition wavelength to the boundary between two PV cells. Longer wavelength light is dispersed to the narrow bandgap cell and shorter wavelength light to the wide bandgap cell. A prototype system is designed with silicon and GaAs PV cells. The holographic lenses are fabricated in Covestro Bayfol HX photopolymer by `stitching' together lens segments through sequential masked exposures. The PV cells and holographic lenses were characterized and the data was used in a raytrace simulation and predicts an improvement in total power output of 15.2% compared to a non-spectrum-splitting reference. A laboratory measurement yielded an improvement in power output of 8.5%.

  20. Design, synthesis and evaluation of a potent substrate analog inhibitor identified by scanning Ala/Phe mutagenesis, mimicking substrate co-evolution, against multidrug-resistant HIV-1 protease

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yedidi, Ravikiran S.; Muhuhi, Joseck M.; Liu, Zhigang

    Highlights: •Inhibitors against MDR HIV-1 protease were designed, synthesized and evaluated. •Lead peptide (6a) showed potent inhibition (IC{sub 50}: 4.4 nM) of MDR HIV-1 protease. •(6a) Showed favorable binding isotherms against NL4-3 and MDR proteases. •(6a) Induced perturbations in the {sup 15}N-HSQC spectrum of MDR HIV-1 protease. •Molecular modeling suggested that (6a) may induce total flap closure inMDR protease. -- Abstract: Multidrug-resistant (MDR) clinical isolate-769, human immunodeficiency virus type-1 (HIV-1) protease (PDB ID: (1TW7)), was shown to exhibit wide-open flaps and an expanded active site cavity, causing loss of contacts with protease inhibitors. In the current study, the expanded activemore » site cavity of MDR769 HIV-1 protease was screened with a series of peptide-inhibitors that were designed to mimic the natural substrate cleavage site, capsid/p2. Scanning Ala/Phe chemical mutagenesis approach was incorporated into the design of the peptide series to mimic the substrate co-evolution. Among the peptides synthesized and evaluated, a lead peptide (6a) with potent activity (IC{sub 50}: 4.4 nM) was identified against the MDR769 HIV-1 protease. Isothermal titration calorimetry data showed favorable binding profile for 6aagainst both wild type and MDR769 HIV-1 protease variants. Nuclear magnetic resonance spectrum of {sup 15}N-labeled MDR769 HIV-1 protease in complex with 6a showed some major perturbations in chemical shift, supporting the peptide induced conformational changes in protease. Modeling analysis revealed multiple contacts between 6a and MDR769 HIV-1 protease. The lead peptide-inhibitor, 6a, with high potency and good binding profile can be used as the basis for developing potent small molecule inhibitors against MDR variants of HIV.« less

  1. Atypical lateralization of ERP response to native and non-native speech in infants at risk for autism spectrum disorder.

    PubMed

    Seery, Anne M; Vogel-Farley, Vanessa; Tager-Flusberg, Helen; Nelson, Charles A

    2013-07-01

    Language impairment is common in autism spectrum disorders (ASD) and is often accompanied by atypical neural lateralization. However, it is unclear when in development language impairment or atypical lateralization first emerges. To address these questions, we recorded event-related-potentials (ERPs) to native and non-native speech contrasts longitudinally in infants at risk for ASD (HRA) over the first year of life to determine whether atypical lateralization is present as an endophenotype early in development and whether these infants show delay in a very basic precursor of language acquisition: phonemic perceptual narrowing. ERP response for the HRA group to a non-native speech contrast revealed a trajectory of perceptual narrowing similar to a group of low-risk controls (LRC), suggesting that phonemic perceptual narrowing does not appear to be delayed in these high-risk infants. In contrast there were significant group differences in the development of lateralized ERP response to speech: between 6 and 12 months the LRC group displayed a lateralized response to the speech sounds, while the HRA group failed to display this pattern. We suggest the possibility that atypical lateralization to speech may be an ASD endophenotype over the first year of life. Copyright © 2012 Elsevier Ltd. All rights reserved.

  2. The structure and spectrum of the accretion shock in the atmospheres of young stars

    NASA Astrophysics Data System (ADS)

    Dodin, Alexandr

    2018-04-01

    The structure and spectrum of the accretion shock have been self-consistently simulated for a wide range of parameters typical for Classical T Tauri Stars (CTTS). Radiative cooling of the shocked gas was calculated, taking into account the self-absorption and non-equilibrium (time-dependent) effects in the level populations. These effects modify the standard cooling curve for an optically thin plasma in coronal equilibrium, however the shape of high-temperature (T > 3 × 105 K) part of the curve remains unchanged. The applied methods allow us to smoothly describe the transition from the cooling flow to the hydrostatic stellar atmosphere. Thanks to this approach, it has been found that the narrow component of He II lines is formed predominantly in the irradiated stationary atmosphere (hotspot), i.e. at velocities of the settling gas <2 km s-1. The structure of the pre-shock region is calculated simultaneously with the heated atmosphere. The simulation shows that the pre-shock gas produces a noticeable emission component in He II lines and practically does not manifest itself in He I lines (λλ 5876, 10830 Å). The ultraviolet spectrum of the hotspot is distorted by the pre-shock gas, namely numerous red-shifted emission and absorption lines overlap each other forming a pseudo-continuum. The spectrum of the accretion region at high pre-shock densities ˜1014 cm-3 is fully formed in the in-falling gas and can be qualitatively described as a spectrum of a star with an effective temperature derived from the Stefan-Boltzmann law via the full energy flux.

  3. An Acrobatic Substrate Metamorphosis Reveals a Requirement for Substrate Conformational Dynamics in Trypsin Proteolysis.

    PubMed

    Kayode, Olumide; Wang, Ruiying; Pendlebury, Devon F; Cohen, Itay; Henin, Rachel D; Hockla, Alexandra; Soares, Alexei S; Papo, Niv; Caulfield, Thomas R; Radisky, Evette S

    2016-12-16

    The molecular basis of enzyme catalytic power and specificity derives from dynamic interactions between enzyme and substrate during catalysis. Although considerable effort has been devoted to understanding how conformational dynamics within enzymes affect catalysis, the role of conformational dynamics within protein substrates has not been addressed. Here, we examine the importance of substrate dynamics in the cleavage of Kunitz-bovine pancreatic trypsin inhibitor protease inhibitors by mesotrypsin, finding that the varied conformational dynamics of structurally similar substrates can profoundly impact the rate of catalysis. A 1.4-Å crystal structure of a mesotrypsin-product complex formed with a rapidly cleaved substrate reveals a dramatic conformational change in the substrate upon proteolysis. By using long all-atom molecular dynamics simulations of acyl-enzyme intermediates with proteolysis rates spanning 3 orders of magnitude, we identify global and local dynamic features of substrates on the nanosecond-microsecond time scale that correlate with enzymatic rates and explain differential susceptibility to proteolysis. By integrating multiple enhanced sampling methods for molecular dynamics, we model a viable conformational pathway between substrate-like and product-like states, linking substrate dynamics on the nanosecond-microsecond time scale with large collective substrate motions on the much slower time scale of catalysis. Our findings implicate substrate flexibility as a critical determinant of catalysis. © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

  4. Site of Allergic Airway Narrowing and the Influence of Exogenous Surfactant in the Brown Norway Rat

    PubMed Central

    Risse, Paul-André; Bullimore, Sharon R.; Benedetti, Andrea; Martin, James G.

    2012-01-01

    Background The parameters RN (Newtonian resistance), G (tissue damping), and H (tissue elastance) of the constant phase model of respiratory mechanics provide information concerning the site of altered mechanical properties of the lung. The aims of this study were to compare the site of allergic airway narrowing implied from respiratory mechanics to a direct assessment by morphometry and to evaluate the effects of exogenous surfactant administration on the site and magnitude of airway narrowing. Methods We induced airway narrowing by ovalbumin sensitization and challenge and we tested the effects of a natural surfactant lacking surfactant proteins A and D (Infasurf®) on airway responses. Sensitized, mechanically ventilated Brown Norway rats underwent an aerosol challenge with 5% ovalbumin or vehicle. Other animals received nebulized surfactant prior to challenge. Three or 20 minutes after ovalbumin challenge, airway luminal areas were assessed on snap-frozen lungs by morphometry. Results At 3 minutes, RN and G detected large airway narrowing whereas at 20 minutes G and H detected small airway narrowing. Surfactant inhibited RN at the peak of the early allergic response and ovalbumin-induced increase in bronchoalveolar lavage fluid cysteinyl leukotrienes and amphiregulin but not IgE-induced mast cell activation in vitro. Conclusion Allergen challenge triggers the rapid onset of large airway narrowing, detected by RN and G, and subsequent peripheral airway narrowing detected by G and H. Surfactant inhibits airway narrowing and reduces mast cell-derived mediators. PMID:22276110

  5. Self-Sustained Mode-3 Tear Controls Dynamics of Narrow Retreating Subduction Zones

    NASA Astrophysics Data System (ADS)

    Munch, J.; Gerya, T.; Ueda, K.

    2017-12-01

    The Caribbean oroclinal basin exhibits several narrow retreating slabs in an oceanic domain. The slabs show a curved shape associated to a bent topography (trench). We propose that the curvature of the topography depends on slab retreat mechanisms following mode-3 tearing at the edges of the slab (out of the plane fracture propagation). While first-order characteristics have been principally reproduced in self-sustained subduction initiation models (Gerya et al., 2015, Nature, 527, 221-225), the relevant observations have not been quantified and the exact mechanism is not understood. In this work, we study the long-term 3D evolution of narrowing oceanic subduction zones during retreat, and investigate the link between mode-3 tear and orocline formation. Numerical experiments are carried out with a thermo-mechanical 3D finite-difference code. To allow the observation of developing topography, the precise location of the internal surface and its evolution by material diffusion is tracked. Retreating subduction is facilitated via a strong age contrast between a young lithosphere window enclosed by shear zones and the surrounding lithosphere. By varying the length and thickness of the shear zones and location of the age transition, the influence of these parameters on the tearing process and the development of topography is assessed. Experiments trigger subduction initiation and slab retreat via fracture zone collapse and spontaneous paired mode-3 tear propagation within the oceanic plate interior. Narrow retreating subducting slabs form as a natural result of the spontaneous paired tearing process. A curved trench forms along with slab retreat. Topography evolution and tearing trajectory appear to be dependent on the initial shear zones and young window dimensions. We also note a strong narrowing of the slab during the retreat (several tens of kilometers over 800 km of retreat). Overall, results indicate that narrowing of retreating slabs is a self

  6. Emergent behavior of cells on microfabricated soft polymeric substrates

    NASA Astrophysics Data System (ADS)

    Anand, Sandeep Venkit

    In recent years, cell based bio-actuators like cardiomyocytes and skeletal muscle cells have emerged as popular choices for powering biological machines consisting of soft polymeric scaffolds at the micro and macro scales. This is owing to their unique ability to generate spontaneous, synchronous contractions either autonomously or under externally applied fields. Most of the biological machine designs reported in literature use single cells or cell clusters conjugated with biocompatible soft polymers like polydimethylsiloxane (PDMS) and hydrogels to produce some form of locomotion by converting chemical energy of the cells to mechanical energy. The mode of locomotion may vary, but the fundamental mechanism that these biological machines exploit to achieve locomotion stems from cell substrate interactions leading to large deformations of the substrates (relative to the cell size). However, the effect of such large scale, dynamic deformation of the substrates on the cellular and cluster level organization of the cells remains elusive. This dissertation tries to explore the emergent behavior of cells on different types of micro-scale deformable, soft polymeric substrates. In the first part of the dissertation, contractile dynamics of primary cardiomyocyte clusters is studied by culturing them on deformable thin polymeric films. The cell clusters beat and generate sufficient forces to deform the substrates out of plane. Over time, the clusters reorient their force dipoles along the direction of maximum compliance. This suggests that the cells are capable of sensing substrate deformations through a mechanosensitive feedback mechanism and dynamically reorganizing themselves. Results are further validated through finite element analysis. The development, characterization and quantification of a novel 1D/2D like polymeric platform for cell culture is presented in the second part. The platform consists of a 2D surface anchoring a long (few millimeters) narrow filament (1D

  7. Substrate-Specific Differential Gene Expression and RNA editing in the Brown Rot Fungus Fomitopsis pinicola.

    PubMed

    Wu, Baojun; Gaskell, Jill; Held, Benjamin W; Toapanta, Cristina; Vuong, Thu; Ahrendt, Steven; Lipzen, Anna; Zhang, Jiwei; Schilling, Jonathan S; Master, Emma; Grigoriev, Igor V; Blanchette, Robert A; Cullen, Dan; Hibbett, David S

    2018-06-08

    Wood-decaying fungi tend to have characteristic substrate ranges that partly define their ecological niche. Fomitopsis pinicola is a brown rot species of Polyporales that is reported on 82 species of softwoods and 42 species of hardwoods. We analyzed gene expression levels and RNA editing profiles of F. pinicola from submerged cultures with ground wood powder (sampled at five days) or solid wood wafers (sampled at ten and thirty days), using aspen, pine, and spruce substrates (aspen was used only in submerged cultures). Fomitopsis pinicola expressed similar sets of wood-degrading enzymes typical of brown rot fungi across all culture conditions and timepoints. Nevertheless, differential gene expression and RNA editing were observed across all pairwise comparisons of substrates and timepoints. Genes exhibiting differential expression and RNA editing encode diverse enzymes with known or potential function in brown rot decay, including laccase, benzoquinone reductase, aryl alcohol oxidase, cytochrome P450s, and various glycoside hydrolases. There was no overlap between differentially expressed and differentially edited genes, suggesting that these may provide F. pinicola with independent mechanisms for responding to different conditions. Comparing transcriptomes from submerged cultures and wood wafers, we found that culture conditions had a greater impact on global expression profiles than substrate wood species. In contrast, the suites of genes subject to RNA editing were much less affected by culture conditions. These findings highlight the need for standardization of culture conditions in studies of gene expression in wood-decaying fungi. IMPORTANCE All species of wood-decaying fungi occur on a characteristic range of substrates (host plants), which may be broad or narrow. Understanding the mechanisms that allow fungi to grow on particular substrates is important for both fungal ecology and applied uses of different feedstocks in industrial processes. We grew the

  8. Narrow-Line Seyfert 1 Galaxies and their place in the Universe

    NASA Astrophysics Data System (ADS)

    Foschini, L.; Colpi, M.; Gallo, L.; Grupe, D.; Komossa, S.; Leighly, K.; Mathur, S.

    In 1978, Davidson and Kinman wrote about Markarian 359: "This unusual object merits further observations...". In 1985, Osterbrock and Pogge defined a new class of active galactic nuclei (AGN), named Narrow-Line Seyfert 1 (NLS1). Twenty-five years later, NLS1s still continue to intrigue and bewilder. NLS1s manifest extreme behaviour at all wavelengths. They exhibit the most extreme X-ray variability seen in radio-quiet AGN, the most intense optical FeII emission, and high rates of star formation. In general, their characteristics are consistent of AGNs with relatively low mass black holes accreting close to the Eddington rate. The 2009 Fermi Gamma-ray Space Telescope discovery of high-energy (E>100 MeV) gamma rays in a handful of NLS1s has established the existence of relativistic jets in these systems -- a fact previously hinted at by the flat radio spectrum and high brightness temperature seen in some objects. Since NLS1 are generally hosted by spirals, this poses some intriguing questions on the galaxy evolution and on how relativistic jets are generated. It is therefore time for the broad community to come together and discuss what we have discovered in the last quarter century and lay the foundation for future work. Workshop Topics: * Central engine: BH mass, accretion disk, BLR/NLR, jet * Host galaxy: morphology, star formation, merging history * NLS1 in the Universe: comparison with other types of AGN, surveys/statistics, formation/merging, cosmological evolution

  9. Substrate quality alters the microbial mineralization of added substrate and soil organic carbon

    NASA Astrophysics Data System (ADS)

    Jagadamma, S.; Mayes, M. A.; Steinweg, J. M.; Schaeffer, S. M.

    2014-09-01

    The rate and extent of decomposition of soil organic carbon (SOC) is dependent, among other factors, on substrate chemistry and microbial dynamics. Our objectives were to understand the influence of substrate chemistry on microbial decomposition of carbon (C), and to use model fitting to quantify differences in pool sizes and mineralization rates. We conducted an incubation experiment for 270 days using four uniformly labeled 14C substrates (glucose, starch, cinnamic acid and stearic acid) on four different soils (a temperate Mollisol, a tropical Ultisol, a sub-arctic Andisol, and an arctic Gelisol). The 14C labeling enabled us to separate CO2 respired from added substrates and from native SOC. Microbial gene copy numbers were quantified at days 4, 30 and 270 using quantitative polymerase chain reaction (qPCR). Substrate C respiration was always higher for glucose than other substrates. Soils with cinnamic and stearic acid lost more native SOC than glucose- and starch-amended soils. Cinnamic and stearic acid amendments also exhibited higher fungal gene copy numbers at the end of incubation compared to unamended soils. We found that 270 days were sufficient to model the decomposition of simple substrates (glucose and starch) with three pools, but were insufficient for more complex substrates (cinnamic and stearic acid) and native SOC. This study reveals that substrate quality exerts considerable control on the microbial decomposition of newly added and native SOC, and demonstrates the need for multi-year incubation experiments to constrain decomposition parameters for the most recalcitrant fractions of SOC and complex substrates.

  10. An Acrobatic Substrate Metamorphosis Reveals a Requirement for Substrate Conformational Dynamics in Trypsin Proteolysis

    DOE PAGES

    Kayode, Olumide; Wang, Ruiying; Pendlebury, Devon F.; ...

    2016-11-03

    The molecular basis of enzyme catalytic power and specificity derives from dynamic interactions between enzyme and substrate during catalysis. While considerable effort has been devoted to understanding how conformational dynamics within enzymes affect catalysis, the role of conformational dynamics within protein substrates has not been addressed. Here in this paper, we examine the importance of substrate dynamics in the cleavage of Kunitz-BPTI protease inhibitors by mesotrypsin, finding that the varied conformational dynamics of structurally similar substrates can profoundly impact the rate of catalysis. A 1.4 Å crystal structure of a mesotrypsin-product complex formed with a rapidly cleaved substrate reveals amore » dramatic conformational change in the substrate upon proteolysis. Using long all-atom molecular dynamics simulations of acyl-enzyme intermediates with proteolysis rates spanning three orders of magnitude, we identify global and local dynamic features of substrates on the ns-μs timescale that correlate with enzymatic rates and explain differential susceptibility to proteolysis. By integrating multiple enhanced sampling methods for molecular dynamics, we model a viable conformational pathway between substratelike and product-like states, linking substrate dynamics on the ns-μs timescale with large collective substrate motions on the much slower timescale of catalysis. Our findings implicate substrate flexibility as a critical determinant of catalysis.« less

  11. Heavy drinking, impulsivity and attentional narrowing following alcohol cue exposure.

    PubMed

    Hicks, Joshua A; Fields, Sherecce; Davis, William E; Gable, Philip A

    2015-08-01

    Research shows that alcohol-related stimuli have the propensity to capture attention among individuals motivated to consume alcohol. Research has further demonstrated that impulsive individuals are especially prone to this type of attentional bias. Recently, it is suggested that alcohol cue exposure can also produce a general narrowing of attention consistent with the activation of approach motivational states. Based on previous models of addiction and recent research on the activation of approach motivational states, we predicted that impulsive individuals would demonstrate a constriction of attentional focus in response to alcohol cue exposure. Participants (n = 392) completed a task assessing attentional breadth in response to alcohol and non-alcohol cues, followed by measures of alcohol use and impulsivity. The findings revealed that impulsivity scores predicted narrowing of attentional scope following the presentation of alcohol cues for heavier drinkers but not for light drinkers. These results suggest that impulsive individuals who drink more heavily demonstrate a narrowing of attention in the presence of alcohol-related incentive cues. Implications for how these findings might account for the link between impulsivity and alcohol use and misuse are discussed.

  12. Fast radio burst search: cross spectrum vs. auto spectrum method

    NASA Astrophysics Data System (ADS)

    Liu, Lei; Zheng, Weimin; Yan, Zhen; Zhang, Juan

    2018-06-01

    The search for fast radio bursts (FRBs) is a hot topic in current radio astronomy studies. In this work, we carry out a single pulse search with a very long baseline interferometry (VLBI) pulsar observation data set using both auto spectrum and cross spectrum search methods. The cross spectrum method, first proposed in Liu et al., maximizes the signal power by fully utilizing the fringe phase information of the baseline cross spectrum. The auto spectrum search method is based on the popular pulsar software package PRESTO, which extracts single pulses from the auto spectrum of each station. According to our comparison, the cross spectrum method is able to enhance the signal power and therefore extract single pulses from data contaminated by high levels of radio frequency interference (RFI), which makes it possible to carry out a search for FRBs in regular VLBI observations when RFI is present.

  13. An Optoelectronic Equivalent Narrowband Filter for High Resolution Optical Spectrum Analysis

    PubMed Central

    Feng, Kunpeng; Cui, Jiwen; Dang, Hong; Wu, Weidong; Sun, Xun; Jiang, Xuelin; Tan, Jiubin

    2017-01-01

    To achieve a narrow bandwidth optical filter with a wide swept range for new generation optical spectrum analysis (OSA) of high performance optical sensors, an optoelectronic equivalent narrowband filter (OENF) was investigated and a swept optical filter with bandwidth of several MHz and sweep range of several tens of nanometers was built using electric filters and a sweep laser as local oscillator (LO). The principle of OENF is introduced and analysis of the OENF system is presented. Two electric filters are optimized to be RBW filters for high and medium spectral resolution applications. Both simulations and experiments are conducted to verify the OENF principle and the results show that the power uncertainty is less than 1.2% and the spectral resolution can reach 6 MHz. Then, a real-time wavelength calibration system consisting of a HCN gas cell and Fabry–Pérot etalon is proposed to guarantee a wavelength accuracy of ±0.4 pm in the C-band and to reduce the influence of phase noise and nonlinear velocity of the LO sweep. Finally, OSA experiments on actual spectra of various optical sensors are conducted using the OENF system. These experimental results indicate that OENF system has an excellent capacity for the analysis of fine spectrum structures. PMID:28208624

  14. An Optoelectronic Equivalent Narrowband Filter for High Resolution Optical Spectrum Analysis.

    PubMed

    Feng, Kunpeng; Cui, Jiwen; Dang, Hong; Wu, Weidong; Sun, Xun; Jiang, Xuelin; Tan, Jiubin

    2017-02-10

    To achieve a narrow bandwidth optical filter with a wide swept range for new generation optical spectrum analysis (OSA) of high performance optical sensors, an optoelectronic equivalent narrowband filter (OENF) was investigated and a swept optical filter with bandwidth of several MHz and sweep range of several tens of nanometers was built using electric filters and a sweep laser as local oscillator (LO). The principle of OENF is introduced and analysis of the OENF system is presented. Two electric filters are optimized to be RBW filters for high and medium spectral resolution applications. Both simulations and experiments are conducted to verify the OENF principle and the results show that the power uncertainty is less than 1.2% and the spectral resolution can reach 6 MHz. Then, a real-time wavelength calibration system consisting of a HCN gas cell and Fabry-Pérot etalon is proposed to guarantee a wavelength accuracy of ±0.4 pm in the C-band and to reduce the influence of phase noise and nonlinear velocity of the LO sweep. Finally, OSA experiments on actual spectra of various optical sensors are conducted using the OENF system. These experimental results indicate that OENF system has an excellent capacity for the analysis of fine spectrum structures.

  15. Surprises from a Deep ASCA Spectrum of the Broad Absorption Line Quasar PHL 5200

    NASA Technical Reports Server (NTRS)

    Mathur, Smita; Matt, G.; Green, P. J.; Elvis, M.; Singh, K. P.

    2002-01-01

    We present a deep (approx. 85 ks) ASCA observation of the prototype broad absorption line quasar (BALQSO) PHL 5200. This is the best X-ray spectrum of a BALQSO yet. We find the following: (1) The source is not intrinsically X-ray weak. (2) The line-of-sight absorption is very strong, with N(sub H) = 5 x 10(exp 23)/sq cm. (3) The absorber does not cover the source completely; the covering fraction is approx. 90%. This is consistent with the large optical polarization observed in this source, implying multiple lines of sight. The most surprising result of this observation is that (4) the spectrum of this BALQSO is not exactly similar to other radio-quiet quasars. The hard X-ray spectrum of PHL 5200 is steep, with the power-law spectral index alpha approx. 1.5. This is similar to the steepest hard X-ray slopes observed so far. At low redshifts, such steep slopes are observed in narrow-line Seyfert 1 (NLS1) galaxies, believed to be accreting at a high Eddington rate. This observation strengthens the analogy between BALQSOs and NLS1 galaxies and supports the hypothesis that BALQSOs represent an early evolutionary state of quasars. It is well accepted that the orientation to the line of sight determines the appearance of a quasar: age seems to play a significant role as well.

  16. Narrow-band radio flares from red dwarf stars

    NASA Technical Reports Server (NTRS)

    White, Stephen M.; Kundu, Mukul R.; Jackson, Peter D.

    1986-01-01

    VLA observations of narrow-band behavior in 20 cm flares from two red dwarf stars, L726 - 8A and AD Leo, are reported. The flare on L726 - 8A was observed at 1415 and 1515 MHz; the flux and the evolution differed significantly at the two frequencies. The flare on AD Leo lasted for 2 hr at 1415 MHz but did not appear at 1515 MHz. The AD Leo flare appears to rule out a source drifting through the stellar corona and is unlikely to be due to plasma emission. In the cyclotron maser model the narrow-band behavior reflects the range of magnetic fields present within the source. The apparent constancy of this field for 2 hr is difficult to understand if magnetic reconnection is the source of energy for the flare. The consistent polarization exhibited by red dwarf flares at 20 cm may be related to stellar activity cycles, and changes in this polarization will permit measuring the length of these cycles.

  17. Nitrification in a zeoponic substrate

    NASA Technical Reports Server (NTRS)

    McGilloway, R. L.; Weaver, R. W.; Ming, D. W.; Gruener, J. E.

    2003-01-01

    Clinoptilolite is a zeolite mineral with high cation exchange capacity used in zeoponic substrates that have been proposed as a solid medium for growing plants or as a fertilizer material. The kinetics of nitrification has not been measured for NH4+ saturated zeoponic substrate. Experiments were conducted to evaluate the production of NO2- and NO3-, and nitrifier populations in zeoponic substrates. Small columns were filled with zeoponic substrate inoculated with a commercial inoculum or soil enrichment culture of nitrifying bacteria. In addition to column studies, a growth chamber study was conducted to evaluate the kinetics of nitrification in zeoponic substrates used to grow radishes (Raphanus sativus L.). The zeoponic substrate provided a readily available source of NH4+, and nitrifying bacteria were active in the substrate. Ammonium oxidation rates in column studies ranged from 5 to 10 micrograms N g-1 substrate h-1, and NO2- oxidation rates were 2 to 9.5 micrograms N g-1 substrate h-1. Rates determined from the growth chamber study were approximately 1.2 micrograms N g-1 substrate h-1. Quantities of NH4+ oxidized to NO2- and NO3- in inoculated zeoponic substrate were in excess of plant up-take. Acidification as a result of NH4+ oxidation resulted in a pH decline, and the zeoponic substrate showed limited buffering capacity.

  18. The Structure of A Pacific Narrow Cold Frontal Rainband

    NASA Technical Reports Server (NTRS)

    Jorgensen, David P.; Pu, Zhaoxia; Persson, Ola; Tao, Wei-Kuo; Starr, David OC. (Technical Monitor)

    2002-01-01

    A NOAA P-3 instrumented aircraft observed an intense, fast-moving narrow cold frontal Farmhand as it approached the Pacific Northwest coast on 19 February 2001 during the Pacific Coastal Jets Experiment. Pseudo-dual-Doppler analyses performed on the airborne Doppler radar data while the frontal system was well offshore indicated that a narrow ribbon of very high radar reflectively convective cores characterized the Farmhand at low levels with echo tops to approximately 4-5 km. The NCFR exhibited gaps in its narrow ribbon of high reflectively, probably as a result of hydrodynamic instability all no its advancing cold pool leading edge. In contrast to some earlier studies of cold frontal rainbands, density current theory described well the motion of the overall front. The character of the updraft structure associated with the heavy rainfall at its leading edge varied across the gap region. The vertical shear of the cross-frontal low-level ambient flow exerted a strong influence on the updraft character, consistent with theoretical arguments developed for squall lines describing the balance of vorticity at the leading edge. In short regions south of the gaps the vertical wind shear was strongest with the updrafts and rain shafts more intense, narrower, and more erect or even downshear tilted. North of the gaps the wind shear weakened with less intense Dihedrals which tilted upshear with a broader band of rainfall. Simulations using a nonhydrostatic mesoscale nested grid model are used to investigate the gap regions, particularly the balance of cold pool induced to pre-frontal ambient shears at the leading edge. Observations confirm the model results that the updraft character depends on the balance of vorticity at the leading edge. Downshear-tilted updrafts imply that convection south of the gap regions would weaken with time relative to the frontal segments north of the gaps since inflow air would be affected by passage through the heavy rain region before ascent

  19. Narrow Networks On The Health Insurance Marketplaces: Prevalence, Pricing, And The Cost Of Network Breadth.

    PubMed

    Dafny, Leemore S; Hendel, Igal; Marone, Victoria; Ody, Christopher

    2017-09-01

    Anecdotal reports and systematic research highlight the prevalence of narrow-network plans on the Affordable Care Act's health insurance Marketplaces. At the same time, Marketplace premiums in the period 2014-16 were much lower than projected by the Congressional Budget Office in 2009. Using detailed data on the breadth of both hospital and physician networks, we studied the prevalence of narrow networks and quantified the association between network breadth and premiums. Controlling for many potentially confounding factors, we found that a plan with narrow physician and hospital networks was 16 percent cheaper than a plan with broad networks for both, and that narrowing the breadth of just one type of network was associated with a 6-9 percent decrease in premiums. Narrow-network plans also have a sizable impact on federal outlays, as they depress the premium of the second-lowest-price silver plan, to which subsidy amounts are linked. Holding all else constant, we estimate that federal subsidies would have been 10.8 percent higher in 2014 had Marketplaces required all plans to offer broad provider networks. Narrow networks are a promising source of potential savings for other segments of the commercial insurance market. Project HOPE—The People-to-People Health Foundation, Inc.

  20. Effect of ferromagnetic exchange field on band gap and spin polarisation of graphene on a TMD substrate

    NASA Astrophysics Data System (ADS)

    Goswami, Partha

    2018-03-01

    We calculate the electronic band dispersion of graphene monolayer on a two-dimensional transition metal dichalcogenide substrate (GrTMD) around K and K^' } points by taking into account the interplay of the ferromagnetic impurities and the substrate-induced interactions. The latter are (strongly enhanced) intrinsic spin-orbit interaction (SOI), the extrinsic Rashba spin-orbit interaction (RSOI) and the one related to the transfer of the electronic charge from graphene to substrate. We introduce exchange field ( M) in the Hamiltonian to take into account the deposition of magnetic impurities on the graphene surface. The cavalcade of the perturbations yield particle-hole symmetric band dispersion with an effective Zeeman field due to the interplay of the substrate-induced interactions with RSOI as the prime player. Our graphical analysis with extremely low-lying states strongly suggests the following: The GrTMDs, such as graphene on WY2, exhibit (direct) band-gap narrowing / widening (Moss-Burstein (MB) gap shift) including the increase in spin polarisation ( P) at low temperature due to the increase in the exchange field ( M) at the Dirac points. The polarisation is found to be electric field tunable as well. Finally, there is anticrossing of non-parabolic bands with opposite spins, the gap closing with same spins, etc. around the Dirac points. A direct electric field control of magnetism at the nanoscale is needed here. The magnetic multiferroics, like BiFeO3 (BFO), are useful for this purpose due to the coupling between the magnetic and electric order parameters.

  1. Simultaneous NuSTAR and XMM-Newton 0.5-80 KeV Spectroscopy of the Narrow-Line Seyfert 1 Galaxy SWIFT J2127.4+5654

    NASA Technical Reports Server (NTRS)

    Marinucci, A.; Matt, G.; Kara, E.; Miniutti, G.; Elvis, M.; Arevalo, P.; Ballantyne, D. R.; Balokovic, M.; Bauer, F.; Brenneman, L.; hide

    2014-01-01

    We present a broad-band spectral analysis of the joint XMM-Newton and Nuclear Spectroscopic Telescope Array observational campaign of the narrow-line Seyfert 1 SWIFT J2127.4+5654, consisting of 300 kiloseconds performed during three XMM-Newton orbits. We detect a relativistic broadened iron K-alpha line originating from the innermost regions of the accretion disc surrounding the central black hole, from which we infer an intermediate spin of a = 0.58 (sup +0.11) (sub -0.17). The intrinsic spectrum is steep (gamma = 2.08 plus or minus 0.01) as commonly found in narrow-line Seyfert 1 galaxies, while the cutoff energy (E (sub c) = 108 (sup +11) (sub -10) kiloelectronvolts) falls within the range observed in broad-line Seyfert 1 galaxies. We measure a low-frequency lag that increases steadily with energy, while at high frequencies, there is a clear lag following the shape of the broad Fe K emission line. Interestingly, the observed Fe K lag in SWIFT J2127.4+5654 is not as broad as in other sources that have maximally spinning black holes. The lag amplitude suggests a continuum-to-reprocessor distance of about 10-20 radius of gyration. These timing results independently support an intermediate black hole spin and a compact corona.

  2. Narrow-angle Astrometry with SUSI

    NASA Astrophysics Data System (ADS)

    Kok, Y.; Ireland, M. J.; Robertson, J. G.; Tuthill, P. G.; Warrington, B. A.; Tango, W. J.

    2014-09-01

    SUSI (Sydney University Stellar Interferometer) is currently being fitted with a 2nd beam combiner, MUSCA (Micro-arcsecond University of Sydney Companion Astrometry), for the purpose of narrow-angle astrometry. With an aim to achieve ˜10 micro-arcseconds of angular resolution at its best, MUSCA allows SUSI to search for planets around bright binary stars, which are its primary targets. While the first beam combiner, PAVO (Precision Astronomical Visible Observations), is used to track stellar fringes during an observation, MUSCA will be used to measure separations of binary stars. MUSCA is a Michelson interferometer and its setup at SUSI will be described in this poster.

  3. Relationship between relative lens position and appositional closure in eyes with narrow angles.

    PubMed

    Otori, Yasumasa; Tomita, Yuki; Hamamoto, Ayumi; Fukui, Kanae; Usui, Shinichi; Tatebayashi, Misako

    2011-03-01

    To investigate the relationship between relative lens position (RLP) and appositional closure in eyes with narrow angles. Ultrasound biomicroscopy (UBM) was used to measure anterior chamber depth (ACD) and lens thickness (LT), and the IOLMaster to measure axial length (AL). The number of quadrants with appositional closure was assessed by UBM under dark conditions. The RLP was calculated thus: RLP = 10 × (ACD + 0.5 LT) /AL. This study comprised 30 consecutive patients (30 eyes) with narrow-angle eyes defined as Shaffer grade 2 or lower and without peripheral anterior synechiae (24 women, 6 men; mean age ± SD, 67.3 ± 10.4 years; range, 42-87 years). Under dark conditions, 66.7% of the eyes with narrow angles showed appositional closure in at least one quadrant. Of the various ocular biometric parameters, only the RLP significantly decreased with appositional closure in at least one quadrant (P = 0.005). A decrease in the RLP can be predictive of appositional closure for narrow-angle eyes under dark conditions.

  4. Analysis of the 3C 445 soft X-ray spectrum as observed by Chandra high-energy gratings

    NASA Astrophysics Data System (ADS)

    Dong, Fu-Tong; Shao, Shu-Hua; Cheng, Yan; Zeng, Jiao-Long

    2018-05-01

    We present a detailed analysis of the soft X-ray emission of 3C 445 using an archival Chandra High Energy Transmission Grating (HETG) spectrum. Highly-ionized H- and He-like Mg, Si and S lines, as well as a resolved low-ionized Si Kα line, are detected in the high resolution spectrum. The He-like triplets of Mg and Si are resolved into individual lines, and the calculated R ratios indicate a high density for the emitter. The low values of G ratios indicate the lines originate from collisionally ionized plasmas. However, the detection of a resolved narrow Ne X radiative recombination continua (RRC) feature in the spectrum seems to prefer a photoionized environment. The spectrum is subsequently modeled with a photoionization model, and the results are compared with those of a collisional model. Through a detailed analysis of the spectrum, we exclude a collisional origin for these emission lines. A one-component photoionization model provides a great fit to the emission features. The best-fit parameters are {log} ξ ={3.3}-0.3+0.4 erg cm s‑1, {n}{{H}}={5}-4.5+15× {10}10 cm‑3 and {N}{{H}}={2.5}-1.7+3.8× {10}20 cm‑2. According to the calculated high density for the emitter, the measured velocity widths of the emission lines and the inferred radial distance (6 × 1014 – 8 × 1015 cm), we suggest the emission lines originating from matter are located in the broad line region (BLR).

  5. Evidence for proton tunneling and a transient covalent flavin-substrate adduct in choline oxidase S101A.

    PubMed

    Uluisik, Rizvan; Romero, Elvira; Gadda, Giovanni

    2017-11-01

    The effect of temperature on the reaction of alcohol oxidation catalyzed by choline oxidase was investigated with the S101A variant of choline oxidase. Anaerobic enzyme reduction in a stopped-flow spectrophotometer was biphasic using either choline or 1,2-[ 2 H 4 ]-choline as a substrate. The limiting rate constants k lim1 and k lim2 at saturating substrate were well separated (k lim1 /k lim2 >9), and were >15-fold slower than for wild-type choline oxidase. Solvent deuterium kinetic isotope effects (KIEs) ~4 established that k lim1 probes the proton transfer from the substrate hydroxyl to a catalytic base. Primary substrate deuterium KIEs ≥7 demonstrated that k lim2 reports on hydride transfer from the choline alkoxide to the flavin. Between 15°C and 39°C the k lim1 and k lim2 values increased with increasing temperature, allowing for the analyses of H + and H - transfers using Eyring and Arrhenius formalisms. Temperature-independent KIE on the k lim1 value ( H2O k lim1 / D2O k lim1 ) suggests that proton transfer occurs within a highly reorganized tunneling-ready-state with a narrow distribution of donor-acceptor distances. Eyring analysis of the k lim2 value gave lines with the slope (choline) >slope (D-choline) , suggesting kinetic complexity. Spectral evidence for the transient occurrence of a covalent flavin-substrate adduct during the first phase of the anaerobic reaction of S101A CHO with choline is presented, supporting the notion that an important role of amino acid residues in the active site of flavin-dependent enzymes is to eliminate alternative reactions of the versatile enzyme-bound flavin for the reaction that needs to be catalyzed. Copyright © 2017 Elsevier B.V. All rights reserved.

  6. Numerical investigation of frequency spectrum in the Hasegawa-Wakatani model

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kim, Juhyung; Terry, P. W.

    2013-10-15

    The wavenumber-frequency spectrum of the two-dimensional Hasegawa-Wakatani model is investigated in the hydrodynamic, intermediate, and adiabatic regimes. A nonlinear frequency and a line width related to energy transfer properties provide a measure of the average frequency and spectral broadening, respectively. In the adiabatic regime, narrow spectra, typical of wave turbulence, are observed with a nonlinear frequency shift in the electron drift direction. In the hydrodynamic regime, broad spectra with almost zero nonlinear frequencies are observed. Nonlinear frequency shifts are shown to be related to nonlinear energy transfer by vorticity advection through the high frequency region of the spectrum. In themore » intermediate regime, the nonlinear frequency shift for density fluctuations is observed to be weaker than that of electrostatic potential fluctuations. The weaker frequency shift of the density fluctuations is due to nonlinear density advection, which favors energy transfer in the low frequency range. Both the nonlinear frequency and the spectral width increase with poloidal wavenumber k{sub y}. In addition, in the adiabatic regime where the nonlinear interactions manifest themselves in the nonlinear frequency shift, the cross-phase between the density and potential fluctuations is observed to match a linear relation, but only if the linear response of the linearly stable eigenmode branch is included. Implications of these numerical observations are discussed.« less

  7. Using multivalency to tailor the superselective binding of polymers on substrates

    NASA Astrophysics Data System (ADS)

    Tito, Nicholas; Frenkel, Daan

    2014-03-01

    Multivalency is a microscopic design concept in which a single nanoscopic entity contains multiple ligands, each of which may bind to multiple receptors on another entity. A useful property of many multivalent systems is ``superselectivity,'' where the fraction of the multivalent species bound to their complementary receptors grows sharply with the total number of receptors available. For example in the past two decades, multivalency has been exploited to develop DNA-coated nanoparticles that self-assemble into aggregates over an extremely narrow temperature window. In this talk, we use analytic and self-consistent field theories to explore the binding of multivalent polymers to receptors on a flat substrate. Discussion will focus on how the sequence, number, and binding strength of ligands along the polymer chain can be used to tune the superselectivity of the system. Comparison with recent experiments on model systems will be presented as time permits. We wish to thank ERC Advanced Grant 227758.

  8. Challenging situations when teaching children with autism spectrum disorders in general physical education.

    PubMed

    Obrusnikova, Iva; Dillon, Suzanna R

    2011-04-01

    As the first step of an instrument development, teaching challenges that occur when students with autism spectrum disorders are educated in general physical education were elicited using Goldfried and D'Zurilla's (1969) behavioral-analytic model. Data were collected from a convenience sample of 43 certified physical educators (29 women and 14 men) using a demographic questionnaire and an elicitation questionnaire. Participants listed 225 teaching challenges, 46% related to cooperative, 31% to competitive, and 24% to individualistic learning situations. Teaching challenges were categorized into nine themes: inattentive and hyperactive behaviors, social impairment, emotional regulation difficulties, difficulties understanding and performing tasks, narrow focus and inflexible adherence to routines and structure, isolation by classmates, negative effects on classmates' learning, and need for support.

  9. Deficit in visual temporal integration in autism spectrum disorders.

    PubMed

    Nakano, Tamami; Ota, Haruhisa; Kato, Nobumasa; Kitazawa, Shigeru

    2010-04-07

    Individuals with autism spectrum disorders (ASD) are superior in processing local features. Frith and Happe conceptualize this cognitive bias as 'weak central coherence', implying that a local enhancement derives from a weakness in integrating local elements into a coherent whole. The suggested deficit has been challenged, however, because individuals with ASD were not found to be inferior to normal controls in holistic perception. In these opposing studies, however, subjects were encouraged to ignore local features and attend to the whole. Therefore, no one has directly tested whether individuals with ASD are able to integrate local elements over time into a whole image. Here, we report a weakness of individuals with ASD in naming familiar objects moved behind a narrow slit, which was worsened by the absence of local salient features. The results indicate that individuals with ASD have a clear deficit in integrating local visual information over time into a global whole, providing direct evidence for the weak central coherence hypothesis.

  10. Narrow band imaging versus autofluorescence imaging for head and neck squamous cell carcinoma detection: a prospective study.

    PubMed

    Ni, X-G; Zhang, Q-Q; Wang, G-Q

    2016-11-01

    This study aimed to compare the diagnostic effectiveness of narrow band imaging and autofluorescence imaging for malignant laryngopharyngeal tumours. Between May 2010 and October 2010, 50 consecutive patients with suspected laryngopharyngeal tumour underwent endoscopic laryngopharynx examination. The morphological characteristics of laryngopharyngeal lesions were analysed using high performance endoscopic systems equipped with narrow band imaging and autofluorescence imaging modes. The diagnostic effectiveness of white light image, narrow band imaging and autofluorescence imaging endoscopy for benign and malignant laryngopharyngeal lesions was evaluated. Under narrow band imaging endoscopy, the superficial microvessels of squamous cell carcinomas appeared as dark brown spots or twisted cords. Under autofluorescence imaging endoscopy, malignant lesions appeared as bright purple. The sensitivity of malignant lesion diagnosis was not significantly different between narrow band imaging and autofluorescence imaging modes, but was better than for white light image endoscopy (χ2 = 12.676, p = 0.002). The diagnostic specificity was significantly better in narrow band imaging mode than in both autofluorescence imaging and white light imaging mode (χ2 = 8.333, p = 0.016). Narrow band imaging endoscopy is the best option for the diagnosis and differential diagnosis of laryngopharyngeal tumours.

  11. Pedestal substrate for coated optics

    DOEpatents

    Hale, Layton C.; Malsbury, Terry N.; Patterson, Steven R.

    2001-01-01

    A pedestal optical substrate that simultaneously provides high substrate dynamic stiffness, provides low surface figure sensitivity to mechanical mounting hardware inputs, and constrains surface figure changes caused by optical coatings to be primarily spherical in nature. The pedestal optical substrate includes a disk-like optic or substrate section having a top surface that is coated, a disk-like base section that provides location at which the substrate can be mounted, and a connecting cylindrical section between the base and optics or substrate sections. The connecting cylindrical section may be attached via three spaced legs or members. However, the pedestal optical substrate can be manufactured from a solid piece of material to form a monolith, thus avoiding joints between the sections, or the disk-like base can be formed separately and connected to the connecting section. By way of example, the pedestal optical substrate may be utilized in the fabrication of optics for an extreme ultraviolet (EUV) lithography imaging system, or in any optical system requiring coated optics and substrates with reduced sensitivity to mechanical mounts.

  12. All-Printed, Self-Aligned Carbon Nanotube Thin-Film Transistors on Imprinted Plastic Substrates.

    PubMed

    Song, Donghoon; Zare Bidoky, Fazel; Hyun, Woo Jin; Walker, S Brett; Lewis, Jennifer A; Frisbie, C Daniel

    2018-05-09

    We present a self-aligned process for printing thin-film transistors (TFTs) on plastic with single-walled carbon nanotube (SWCNT) networks as the channel material. The SCALE (self-aligned capillarity-assisted lithography for electronics) process combines imprint lithography with inkjet printing. Specifically, inks are jetted into imprinted reservoirs, where they then flow into narrow device cavities due to capillarity. Here, we incorporate a composite high- k gate dielectric and an aligned conducting polymer gate electrode in the SCALE process to enable a smaller areal footprint than prior designs that yields low-voltage SWCNT TFTs with average p-type carrier mobilities of 4 cm 2 /V·s and ON/OFF current ratios of 10 4 . Our work demonstrates the promising potential of the SCALE process to fabricate SWCNT-based TFTs with favorable I- V characteristics on plastic substrates.

  13. Narrow-field-of-view bathymetrical lidar: theory and field test

    NASA Astrophysics Data System (ADS)

    Feygels, Viktor I.; Wright, C. Wayne; Kopilevich, Yuri I.; Surkov, Alexey I.

    2003-11-01

    The purpose of this paper is to derive a reliable theory to predict the performance of a narrow-FOV bathymetric lidar. A fundamental discrepancy between the theoretical estimate and experimental results was the inspiration for the work presented here Meeting oceanographic mapping requirements is a critically important goal for littoral laser bathymetry. In contrast to traditional airborne lidar system which are optimized for recovering signals from the deepest possible waters , the above challenge may be met with a radical narrowing to the lidar transmit beam and receiver field of view (FOV) employed in EAARL (Experimental Advanced Airborne Research Lidar, NASA). In this paper we discuss theoretical analysis carried out on the basis of a sophisticated "multiple-forward scattering and single-backscattering model" for lidar return signals allows a quantitative estimation of the advantages of a narrow-FOV system over traditional bathymetric lidars (SHOALS-400, SHOALS-100, LADS Mk II) when used in clear shallow-water cases. Some of those advantages are: ¸ Increase in bottom definition (or reduced false-alarm probability) due to the enhanced contrast of the bottom return over the background backscatter from the water column, ¸ Enhancement in depth measurement accuracy resulting from narrower bottom return pulse width, ¸ Reduction of post-surface return effects in the lidar photo-multiplier detector due to a more rapid decay of water column backscatter, ¸ Greatly improved rejection of ambient light permitting lidar operations in all zenith sun angles and flight directions. The model computations make it possible to estimate the maximal operational depth for the system under consideration by the implementation of statistical theory of detectability. These computations depend on the prevailing seawater optical properties and lidar parameters. The theoretical predictions are compared with results obtained in the field test of the EAARL system carried out in Florida Keys

  14. Metallic coatings on silicon substrates, and methods of forming metallic coatings on silicon substrates

    DOEpatents

    Branagan, Daniel J [Idaho Falls, ID; Hyde, Timothy A [Idaho Falls, ID; Fincke, James R [Los Alamos, NM

    2008-03-11

    The invention includes methods of forming a metallic coating on a substrate which contains silicon. A metallic glass layer is formed over a silicon surface of the substrate. The invention includes methods of protecting a silicon substrate. The substrate is provided within a deposition chamber along with a deposition target. Material from the deposition target is deposited over at least a portion of the silicon substrate to form a protective layer or structure which contains metallic glass. The metallic glass comprises iron and one or more of B, Si, P and C. The invention includes structures which have a substrate containing silicon and a metallic layer over the substrate. The metallic layer contains less than or equal to about 2 weight % carbon and has a hardness of at least 9.2 GPa. The metallic layer can have an amorphous microstructure or can be devitrified to have a nanocrystalline microstructure.

  15. Towards rhombohedral SiGe epitaxy on 150mm c-plane sapphire substrates

    NASA Astrophysics Data System (ADS)

    Duzik, Adam J.; Park, Yeonjoon; Choi, Sang H.

    2015-04-01

    Previous work demonstrated for the first time the ability to epitaxially grow uniform single crystal diamond cubic SiGe (111) films on trigonal sapphire (0001) substrates. While SiGe (111) forms two possible crystallographic twins on sapphire (0001), films consisting primarily of one twin were produced on up to 99.95% of the total wafer area. This permits new bandgap engineering possibilities and improved group IV based devices that can exploit the higher carrier mobility in Ge compared to Si. Models are proposed on the epitaxy of such dissimilar crystal structures based on the energetic favorability of crystallographic twins and surface reconstructions. This new method permits Ge (111) on sapphire (0001) epitaxy, rendering Ge an economically feasible replacement for Si in some applications, including higher efficiency Si/Ge/Si quantum well solar cells. Epitaxial SiGe films on sapphire showed a 280% increase in electron mobility and a 500% increase in hole mobility over single crystal Si. Moreover, Ge possesses a wider bandgap for solar spectrum conversion than Si, while the transparent sapphire substrate permits an inverted device structure, increasing the total efficiency to an estimated 30-40%, much higher than traditional Si solar cells. Hall Effect mobility measurements of the Ge layer in the Si/Ge/Si quantum well structure were performed to demonstrate the advantage in carrier mobility over a pure Si solar cell. Another application comes in the use of microelectromechanical devices technology, where high-resistivity Si is currently used as a substrate. Sapphire is a more resistive substrate and offers better performance via lower parasitic capacitance and higher film carrier mobility over the current Si-based technology.

  16. Quantum fluctuations increase the self-diffusive motion of para-hydrogen in narrow carbon nanotubes.

    PubMed

    Kowalczyk, Piotr; Gauden, Piotr A; Terzyk, Artur P; Furmaniak, Sylwester

    2011-05-28

    Quantum fluctuations significantly increase the self-diffusive motion of para-hydrogen adsorbed in narrow carbon nanotubes at 30 K comparing to its classical counterpart. Rigorous Feynman's path integral calculations reveal that self-diffusive motion of para-hydrogen in a narrow (6,6) carbon nanotube at 30 K and pore densities below ∼29 mmol cm(-3) is one order of magnitude faster than the classical counterpart. We find that the zero-point energy and tunneling significantly smoothed out the free energy landscape of para-hydrogen molecules adsorbed in a narrow (6,6) carbon nanotube. This promotes a delocalization of the confined para-hydrogen at 30 K (i.e., population of unclassical paths due to quantum effects). Contrary the self-diffusive motion of classical para-hydrogen molecules in a narrow (6,6) carbon nanotube at 30 K is very slow. This is because classical para-hydrogen molecules undergo highly correlated movement when their collision diameter approached the carbon nanotube size (i.e., anomalous diffusion in quasi-one dimensional pores). On the basis of current results we predict that narrow single-walled carbon nanotubes are promising nanoporous molecular sieves being able to separate para-hydrogen molecules from mixtures of classical particles at cryogenic temperatures. This journal is © the Owner Societies 2011

  17. Assessment of atherosclerotic luminal narrowing of coronary arteries based on morphometrically generated visual guides.

    PubMed

    Barth, Rolf F; Kellough, David A; Allenby, Patricia; Blower, Luke E; Hammond, Scott H; Allenby, Greg M; Buja, L Maximilian

    Determination of the degree of stenosis of atherosclerotic coronary arteries is an important part of postmortem examination of the heart, but, unfortunately, estimation of the degree of luminal narrowing can be imprecise and tends to be approximations. Visual guides can be useful to assess this, but earlier attempts to develop such guides did not employ digital technology. Using this approach, we have developed two computer-generated morphometric guides to estimate the degree of luminal narrowing of atherosclerotic coronary arteries. The first is based on symmetric or eccentric circular or crescentic narrowing of the vessel lumen and the second on either slit-like or irregularly shaped narrowing of the vessel lumens. Using the Aperio ScanScope XT at a magnification of 20× we created digital whole-slide images of 20 representative microscopic cross sections of the left anterior descending (LAD) coronary artery, stained with either hematoxylin and eosin (H&E) or Movat's pentachrome stain. These cross sections illustrated a variety of luminal profiles and degrees of stenosis. Three representative types of images were selected and a visual guide was constructed with Adobe Photoshop CS5. Using the "Scale" and "Measurement" tools, we created a series of representations of stenosis with luminal cross sections depicting 20%, 40%, 60%, 70%, 80%, and 90% occlusion of the LAD branch. Four pathologists independently reviewed and scored the degree of atherosclerotic luminal narrowing based on our visual guides. In addition, digital technology was employed to determine the degree of narrowing by measuring the cross-sectional area of the 20 microscopic sections of the vessels, first assuming no narrowing and then comparing this to the percent of narrowing determined by precise measurement. Two of the observers were very experienced general autopsy pathologists, one was a first-year pathology resident on his first rotation on the autopsy service, and the fourth observer was a

  18. Mapping protease substrates using a biotinylated phage substrate library.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Scholle, M. D.; Kriplani, U.; Pabon, A.

    We describe a bacteriophage M13 substrate library encoding the AviTag (BirA substrate) and combinatorial heptamer peptides displayed at the N terminus of the mature form of capsid protein III. Phages are biotinylated efficiently (> or = 50%) when grown in E. coli cells coexpressing BirA, and such viral particles can be immobilized on a streptavidin-coated support and released by protease cleavage within the combinatorial peptide. We have used this library to map the specificity of human Factor Xa and a neuropeptidase, neurolysin (EC3.4.24.16). Validation by analysis of isolated peptide substrates has revealed that neurolysin recognizes the motif hydrophobic-X-Pro-Arg-hydrophobic, where Arg-hydrophobicmore » is the scissile bond.« less

  19. Solid-State Laser Source of Tunable Narrow-Bandwidth Ultraviolet Radiation

    NASA Technical Reports Server (NTRS)

    Goldberg, Lew; Kliner, Dahv A.; Koplow, Jeffrey P.

    1998-01-01

    A solid-state laser source of tunable and narrow-bandwidth UV light is disclosed. The system relies on light from a diode laser that preferably generates light at infrared frequencies. The light from the seed diode laser is pulse amplified in a light amplifier, and converted into the ultraviolet by frequency tripling, quadrupling, or quintupling the infrared light. The narrow bandwidth, or relatively pure light, of the seed laser is preserved, and the pulse amplifier generates high peak light powers to increase the efficiency of the nonlinear crystals in the frequency conversion stage. Higher output powers may be obtained by adding a fiber amplifier to power amplify the pulsed laser light prior to conversion.

  20. Magnetic Field Generation During the Collision of Narrow Plasma Clouds

    NASA Astrophysics Data System (ADS)

    Sakai, Jun-ichi; Kazimura, Yoshihiro; Haruki, Takayuki

    1999-06-01

    We investigate the dynamics of the collision of narrow plasma clouds,whose transverse dimension is on the order of the electron skin depth.A 2D3V (two dimensions in space and three dimensions in velocity space)particle-in-cell (PIC) collisionless relativistic code is used toshow the generation of a quasi-staticmagnetic field during the collision of narrow plasma clouds both inelectron-ion and electron-positron (pair) plasmas. The localizedstrong magnetic fluxes result in the generation of the charge separationwith complicated structures, which may be sources of electromagneticas well as Langmuir waves. We also present one applicationof this process, which occurs during coalescence of magnetic islandsin a current sheet of pair plasmas.

  1. [Constitutional narrowing of the cervical spinal canal. Radiological and clinical findings].

    PubMed

    Ritter, G; Rittmeyer, K; Hopf, H C

    1975-02-21

    A constitutional narrowing of the cervical spinal canal was seen in 31 patients with neurological disorders. The ratio of the inner diameter of the spinal canal to the diameter of the vertebral body was smaller than 1 (normal greater than 1). Clinical signs were observed from 45 years upwards where reactivedegenerative changes cause additional narrowing. The majority of patients were male, predominantly heavy manual labourers. There is often a trauma preceding. On myelography multilocular deformations of the spinal subarachnoid space and nerve roots are seen. On the mechanical narrowing of the spinal canal a vascular factor supervenes, caused by exostoses, intervertebral disc protrusions, and fibrosing processes. Clinically a chronic progressive spinal transection syndrome (cervical myelopathy) dominates besides a multilocular root involvement. Posterior column sensibility is predominantly lost. Pain in the extemities and the cervical column is an early symptom. Non-specific CSF changes occur frequently. In case of root involvement the electromyogram is pathological. The prognosis is bad. Operation can only remove reactive processes but not the constitutional anomaly.

  2. Assessment of narrow angles by gonioscopy, Van Herick method and anterior segment optical coherence tomography.

    PubMed

    Park, Seong Bae; Sung, Kyung Rim; Kang, Sung Yung; Jo, Jung Woo; Lee, Kyoung Sub; Kook, Michael S

    2011-07-01

    To evaluate anterior chamber (AC) angles using gonioscopy, Van Herick technique and anterior segment optical coherence tomography (AS-OCT). One hundred forty-eight consecutive subjects were enrolled. The agreement between any two of three diagnostic methods, gonioscopy, AS-OCT and Van Herick, was calculated in narrow-angle patients. The area under receiver-operating characteristic curves (AUC) for discriminating between narrow and open angles determined by gonioscopy was calculated in all participants for AS-OCT parameter angle opening distance (AOD), angle recess area, trabecular iris surface area and anterior chamber depth (ACD). As a subgroup analysis, capability of AS-OCT parameters for detecting angle closure defined by AS-OCT was assessed in narrow-angle patients. The agreement between the Van Herick method and gonioscopy in detecting angle closure was excellent in narrow angles (κ = 0.80, temporal; κ = 0.82, nasal). However, agreement between gonioscopy and AS-OCT and between the Van Herick method and AS-OCT was poor (κ = 0.11-0.16). Discrimination capability of AS-OCT parameters between open and narrow angles determined by gonioscopy was excellent for all AS-OCT parameters (AUC, temporal: AOD500 = 0.96, nasal: AOD500 = 0.99). The AUCs for detecting angle closure defined by AS-OCT image in narrow angle subjects was good for all AS-OCT parameters (AUC, 0.80-0.94) except for ACD (temporal: ACD = 0.70, nasal: ACD = 0.63). Assessment of narrow angles by gonioscopy and the Van Herick technique showed good agreement, but both measurements revealed poor agreement with AS-OCT. The angle closure detection capability of AS-OCT parameters was excellent; however, it was slightly lower in ACD.

  3. XTE Proposal #20102--"SS 433's High Energy Spectrum"

    NASA Technical Reports Server (NTRS)

    Band, David L.; Blanco, P.; Rothschild, R.; Kawai, N.; Kotani, T.; Oka, T.; Wagner, R. M.; Hjellming, R.; Rupen, M.; Brinkmann, W.

    1999-01-01

    We observed the jet-producing compact binary system SS 433 with RXTE during three multiwavelength campaigns, the first in conjunction with ASCA observations, the second simultaneous with a VLA-VLBA-MERLIN campaign, and the third associated with a Nobeyama millimeter-band campaign. All these campaigns included optical observations. Occurring at different jet precession and binary phases, the observations also monitored the system during a radio flare. The data provide SS 433's X-ray spectrum over more than an energy decade, and track the spectral variations as the X-ray source was partially eclipsed. The continuum can be modeled as a power law with an exponential cutoff, which can be detected to approximately 50 keV. Strong line emission is evident in the 5-10 keV range which can be modeled as a broad line whose energy is precession independent and a narrow line whose energy does vary with jet precession phase; this line model is clearly an over simplification since the PCA does not have sufficient energy resolution to detect the lines ASCA observed. The eclipses are deeper at high energy and at jet precession phases when the jets are more inclined towards and away from us. A large radio flare occurred between two sets of X-ray monitoring observations; an X-ray observation at the peak of the flare found a softer spectrum with a flux approximately 1/3 that of the quiescent level.

  4. Atomic Dynamics in Simple Liquid: de Gennes Narrowing Revisited

    NASA Astrophysics Data System (ADS)

    Wu, Bin; Iwashita, Takuya; Egami, Takeshi

    2018-03-01

    The de Gennes narrowing phenomenon is frequently observed by neutron or x -ray scattering measurements of the dynamics of complex systems, such as liquids, proteins, colloids, and polymers. The characteristic slowing down of dynamics in the vicinity of the maximum of the total scattering intensity is commonly attributed to enhanced cooperativity. In this Letter, we present an alternative view on its origin through the examination of the time-dependent pair correlation function, the van Hove correlation function, for a model liquid in two, three, and four dimensions. We find that the relaxation time increases monotonically with distance and the dependence on distance varies with dimension. We propose a heuristic explanation of this dependence based on a simple geometrical model. This finding sheds new light on the interpretation of the de Gennes narrowing phenomenon and the α -relaxation time.

  5. `Fingerprint' Fine Structure in the Solar Decametric Radio Spectrum Solar Physics

    NASA Astrophysics Data System (ADS)

    Zlotnik, E. Y.; Zaitsev, V. V.; Melnik, V. N.; Konovalenko, A. A.; Dorovskyy, V. V.

    2015-07-01

    We study a unique fine structure in the dynamic spectrum of the solar radio emission discovered by the UTR-2 radio telescope (Kharkiv, Ukraine) in the frequency band of 20 - 30 MHz. The structure was observed against the background of a broadband type IV radio burst and consisted of parallel drifting narrow bands of enhanced emission and absorption on the background emission. The observed structure differs from the widely known zebra pattern at meter and decimeter wavelengths by the opposite directions of the frequency drift within a single stripe at a given time. We show that the observed properties can be understood in the framework of the radiation mechanism by virtue of the double plasma resonance effect in a nonuniform coronal magnetic trap. We propose a source model providing the observed frequency drift of the stripes.

  6. Assessing the Temperature Dependence of Narrow-Band Raman Water Vapor Lidar Measurements: A Practical Approach

    NASA Technical Reports Server (NTRS)

    Whiteman, David N.; Venable, Demetrius D.; Walker, Monique; Cardirola, Martin; Sakai, Tetsu; Veselovskii, Igor

    2013-01-01

    Narrow-band detection of the Raman water vapor spectrum using the lidar technique introduces a concern over the temperature dependence of the Raman spectrum. Various groups have addressed this issue either by trying to minimize the temperature dependence to the point where it can be ignored or by correcting for whatever degree of temperature dependence exists. The traditional technique for performing either of these entails accurately measuring both the laser output wavelength and the water vapor spectral passband with combined uncertainty of approximately 0.01 nm. However, uncertainty in interference filter center wavelengths and laser output wavelengths can be this large or larger. These combined uncertainties translate into uncertainties in the magnitude of the temperature dependence of the Raman lidar water vapor measurement of 3% or more. We present here an alternate approach for accurately determining the temperature dependence of the Raman lidar water vapor measurement. This alternate approach entails acquiring sequential atmospheric profiles using the lidar while scanning the channel passband across portions of the Raman water vapor Q-branch. This scanning is accomplished either by tilt-tuning an interference filter or by scanning the output of a spectrometer. Through this process a peak in the transmitted intensity can be discerned in a manner that defines the spectral location of the channel passband with respect to the laser output wavelength to much higher accuracy than that achieved with standard laboratory techniques. Given the peak of the water vapor signal intensity curve, determined using the techniques described here, and an approximate knowledge of atmospheric temperature, the temperature dependence of a given Raman lidar profile can be determined with accuracy of 0.5% or better. A Mathematica notebook that demonstrates the calculations used here is available from the lead author.

  7. World Food Resources and Population: The Narrowing Margin.

    ERIC Educational Resources Information Center

    Brown, Lester R.

    1981-01-01

    This bulletin examines the narrowing margin between global food production and population growth. Between 1950 and 1971, world grain production nearly doubled and per capita production increased 31 percent. During the 1970s, gains in output barely kept pace with population growth, consumption per person declined in sub-Saharan Africa and parts of…

  8. 33 CFR 117.561 - Kent Island Narrows.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... the U.S. Route 50/301 bridge, mile 1.0, Kent Island Narrows, operates as follows: (a) From November 1 through April 30, the draw shall open on signal from 6 a.m. to 6 p.m. but need not be opened from 6 p.m. to 6 a.m. (b) From May 1 through October 31, the draw shall open on signal on the hour and half-hour...

  9. 33 CFR 117.561 - Kent Island Narrows.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... the U.S. Route 50/301 bridge, mile 1.0, Kent Island Narrows, operates as follows: (a) From November 1 through April 30, the draw shall open on signal from 6 a.m. to 6 p.m. but need not be opened from 6 p.m. to 6 a.m. (b) From May 1 through October 31, the draw shall open on signal on the hour and half-hour...

  10. 33 CFR 117.561 - Kent Island Narrows.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... the U.S. Route 50/301 bridge, mile 1.0, Kent Island Narrows, operates as follows: (a) From November 1 through April 30, the draw shall open on signal from 6 a.m. to 6 p.m. but need not be opened from 6 p.m. to 6 a.m. (b) From May 1 through October 31, the draw shall open on signal on the hour and half-hour...

  11. 33 CFR 117.561 - Kent Island Narrows.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... the U.S. Route 50/301 bridge, mile 1.0, Kent Island Narrows, operates as follows: (a) From November 1 through April 30, the draw shall open on signal from 6 a.m. to 6 p.m. but need not be opened from 6 p.m. to 6 a.m. (b) From May 1 through October 31, the draw shall open on signal on the hour and half-hour...

  12. 33 CFR 117.561 - Kent Island Narrows.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... the U.S. Route 50/301 bridge, mile 1.0, Kent Island Narrows, operates as follows: (a) From November 1 through April 30, the draw shall open on signal from 6 a.m. to 6 p.m. but need not be opened from 6 p.m. to 6 a.m. (b) From May 1 through October 31, the draw shall open on signal on the hour and half-hour...

  13. Population differences in dysmorphic features among children with fetal alcohol spectrum disorders.

    PubMed

    May, Philip A; Gossage, J Phillip; Smith, Matthew; Tabachnick, Barbara G; Robinson, Luther K; Manning, Melanie; Cecanti, Mauro; Jones, Kenneth Lyons; Khaole, Nathaniel; Buckley, David; Kalberg, Wendy O; Trujillo, Phyllis M; Hoyme, H Eugene

    2010-05-01

    To examine the variation in significant dysmorphic features in children from 3 different populations with the most dysmorphic forms of fetal alcohol spectrum disorders, fetal alcohol syndrome (FAS), and partial fetal alcohol syndrome (PFAS). Advanced multiple regression techniques are used to determine the discriminating physical features in the diagnosis of FAS and PFAS among children from Northern Plains Indian communities, South Africa, and Italy. Within the range of physical features used to identify children with fetal alcohol spectrum disorders, specifically FAS and PFAS, there is some significant variation in salient diagnostic features from one population to the next. Intraclass correlations in diagnostic features between these 3 populations is 0.20, indicating that about 20% of the variability in dysmorphology core features is associated with location and, therefore, specific racial/ethnic population. The highly significant diagnostic indicators present in each population are identified for the full samples of FAS, PFAS, and normals and also among children with FAS only. A multilevel model for these populations combined indicates that these variables predict dysmorphology unambiguously: small palpebral fissures, narrow vermillion, smooth philtrum, flat nasal bridge, and fifth finger clinodactyly. Long philtrum varies substantially as a predictor in the 3 populations. Predictors not significantly related to fetal alcohol spectrum disorders dysmorphology across the 3 populations are centile of height (except in Italy) strabismus, interpupilary distance, intercanthal distance, and heart murmurs. The dysmorphology associated with FAS and PFAS vary across populations, yet a particular array of common features occurs in each population, which permits a consistent diagnosis across populations.

  14. Evaporation of liquid droplets on solid substrates. II. Periodic substrates with moving contact lines

    NASA Astrophysics Data System (ADS)

    Amini, Amirhossein; Homsy, G. M.

    2017-04-01

    Experiments on evaporating droplets on structured surfaces have shown that the contact line does not move with constant speed, but rather in a steplike "stick-slip" fashion. As a first step in understanding such behavior, we study the evaporation of a two-dimensional volatile liquid droplet on a nonplanar heated solid substrate with a moving contact line and fixed contact angle. The model for the flat case is adapted to include curved substrates, numerical solutions are achieved for various periodic and quasiperiodic substrate profiles, and the dynamics of the contact line and the apparent contact angle are studied. In contrast with our results for a flat substrate, for which the contact line recedes in a nearly constant speed, we observe that the contact line speed and position show significant time variation and that the contact line moves in an approximate steplike fashion on relatively steep substrates. For the simplest case of a periodic substrate, we find that the apparent contact angle is periodic in time. For doubly periodic substrates, we find that the apparent contact angle is periodic and that the problem exhibits a phase-locking behavior. For multimode quasiperiodic substrates, we find the contact line behavior to be temporally complex and not only limited to a stick-slip motion. In all cases, we find that the overall evaporation is increased relative to the flat substrate.

  15. Recovery of EUVL substrates

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vernon, S.P.; Baker, S.L.

    1995-01-19

    Mo/Si multilayers, were removed from superpolished zerodur and fused silica substrates with a dry etching process that, under suitable processing conditions, produces negligible change in either the substrate surface figure or surface roughness. Full recovery of the initial normal incidence extreme ultra-violet (EUV) reflectance response has been demonstrated on reprocessed substrates.

  16. Transition from intelligence cycle to intelligence process: the network-centric intelligence in narrow seas

    NASA Astrophysics Data System (ADS)

    Büker, Engin

    2015-05-01

    The defence technologies which have been developing and changing rapidly, today make it difficult to be able to foresee the next environment and spectrum of warfare. When said change and development is looked in specific to the naval operations, it can be said that the possible battlefield and scenarios to be developed in the near and middle terms (5-20 years) are more clarified with compare to other force components. Network Centric Naval Warfare Concept that was developed for the floating, diving and flying fleet platforms which serves away from its own mainland for miles, will keep its significance in the future. Accordingly, Network Centric Intelligence structure completely integrating with the command and control systems will have relatively more importance. This study will firstly try to figure out the transition from the traditional intelligence cycle that is still used in conventional war to Network Centric Intelligence Production Process. In the last part, the use of this new approach on the base of UAV that is alternative to satellite based command control and data transfer systems in the joint operations in narrow seas will be examined, a model suggestion for the use of operative and strategic UAVs which are assured within the scope of the NATO AGS2 for this aim will be brought.

  17. Conditions and phase shift of fluid resonance in narrow gaps of bottom mounted caissons

    NASA Astrophysics Data System (ADS)

    Zhu, Da-tong; Wang, Xing-gang; Liu, Qing-jun

    2017-12-01

    This paper studies the viscid and inviscid fluid resonance in gaps of bottom mounted caissons on the basis of the plane wave hypothesis and full wave model. The theoretical analysis and the numerical results demonstrate that the condition for the appearance of fluid resonance in narrow gaps is kh=(2 n+1)π ( n=0, 1, 2, 3, …), rather than kh= nπ ( n=0, 1, 2, 3, …); the transmission peaks in viscid fluid are related to the resonance peaks in the gaps. k and h stand for the wave number and the gap length. The combination of the plane wave hypothesis or the full wave model with the local viscosity model can accurately determine the heights and the locations of the resonance peaks. The upper bound for the appearance of fluid resonance in gaps is 2 b/ L<1 (2 b, grating constant; L, wave length) and the lower bound is h/ b≤1. The main reason for the phase shift of the resonance peaks is the inductive factors. The number of resonance peaks in the spectrum curve is dependent on the ratio of the gap length to the grating constant. The heights and the positions of the resonance peaks predicted by the present models agree well with the experimental data.

  18. Perovskite nanocrystals: across-dimensional attachment, film-scale assembly on a flexible substrate and their fluorescence properties

    NASA Astrophysics Data System (ADS)

    Huang, Wenyi; Liu, Jiajia; Bai, Bing; Huang, Liu; Xu, Meng; Liu, Jia; Rong, Hongpan; Zhang, Jiatao

    2018-03-01

    Perovskite nanocrystals (NCs), which are a good fluorescence candidate with excellent photoelectric properties, have opened new avenues in the fabrication of highly efficient solar cells, light-emitting diodes (LEDs), and other optoelectronic devices. Further advances will rely on the multitude of compositional, structural variants that enable the formation of lower-dimensionality layered and three-dimensional (3D) perovskites with architectural innovations. In this work, the perovskite film was fabricated on a flexible substrate using simple dip-coating technology and 3D assemblies of perovskite NCs were obtained through an attachment process. Original perovskite NCs had a rectangular or square morphology with high particle uniformity and the narrow and symmetric fluorescence emission peak was adjustable at 515-527 nm. The controllable self-assembly of the micron size cuboid-like 3D assembly had an apparent enhancement on peak (111) in the x-ray diffraction (XRD) pattern. Surface ligands not only play a role in the attachment process but also keep the independence of each NC in 3D assemblies. Such assembly of the perovskite film maintained the original perovskite NCs fluorescence emission peak and narrow full width at the half-maximum (FWHM), which is of great importance for the investigation of future devices.

  19. 17 CFR 41.14 - Transition period for indexes that cease being narrow-based security indexes.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... day tolerance provision. An index that is a narrow-based security index that becomes a broad-based... than forty-five days. An index that is a narrow-based security index that becomes a broad-based...

  20. Atypical neural substrates of Embedded Figures Task performance in children with Autism Spectrum Disorder.

    PubMed

    Lee, Philip S; Foss-Feig, Jennifer; Henderson, Joshua G; Kenworthy, Lauren E; Gilotty, Lisa; Gaillard, William D; Vaidya, Chandan J

    2007-10-15

    Superior performance on the Embedded Figures Task (EFT) has been attributed to weak central coherence in perceptual processing in Autism Spectrum Disorder (ASD). The present study used functional magnetic resonance imaging to examine the neural basis of EFT performance in 7- to 12-year-old ASD children and age- and IQ-matched controls. ASD children activated only a subset of the distributed network of regions activated in controls. In frontal cortex, control children activated left dorsolateral, medial and dorsal premotor regions whereas ASD children only activated the dorsal premotor region. In parietal and occipital cortices, activation was bilateral in control children but unilateral (left superior parietal and right occipital) in ASD children. Further, extensive bilateral ventral temporal activation was observed in control, but not ASD children. ASD children performed the EFT at the same level as controls but with reduced cortical involvement, suggesting that disembedded visual processing is accomplished parsimoniously by ASD relative to typically developing brains.

  1. Adult Autism Subthreshold Spectrum (AdAS Spectrum): Validation of a questionnaire investigating subthreshold autism spectrum.

    PubMed

    Dell'Osso, L; Gesi, C; Massimetti, E; Cremone, I M; Barbuti, M; Maccariello, G; Moroni, I; Barlati, S; Castellini, G; Luciano, M; Bossini, L; Rocchetti, M; Signorelli, M; Aguglia, E; Fagiolini, A; Politi, P; Ricca, V; Vita, A; Carmassi, C; Maj, M

    2017-02-01

    Increasing literature has shown the usefulness of a dimensional approach to autism. The present study aimed to determine the psychometric properties of the Adult Autism Subthreshold Spectrum (AdAS Spectrum), a new questionnaire specifically tailored to assess subthreshold forms of autism spectrum disorder (ASD) in adulthood. 102 adults endorsing at least one DSM-5 symptom criterion for ASD (ASDc), 143 adults diagnosed with a feeding and eating disorder (FED), and 160 subjects with no mental disorders (CTL), were recruited from 7 Italian University Departments of Psychiatry and administered the following: SCID-5, Autism-Spectrum Quotient (AQ), Ritvo Autism and Asperger Diagnostic Scale 14-item version (RAADS-14), and AdAS Spectrum. The AdAS Spectrum demonstrated excellent internal consistency for the total score (Kuder-Richardson's coefficient=.964) as well as for five out of seven domains (all coefficients>.80) and sound test-retest reliability (ICC=.976). The total and domain AdAS Spectrum scores showed a moderate to strong (>.50) positive correlation with one another and with the AQ and RAADS-14 total scores. ASDc subjects reported significantly higher AdAS Spectrum total scores than both FED (p<.001) and CTL (p<.001), and significantly higher scores on the Childhood/adolescence, Verbal communication, Empathy, Inflexibility and adherence to routine, and Restricted interests and rumination domains (all p<.001) than FED, while on all domains compared to CTL. CTL displayed significantly lower total and domain scores than FED (all p<.001). A significant effect of gender emerged for the Hyper- and hyporeactivity to sensory input domain, with women showing higher scores than men (p=.003). A Diagnosis* Gender interaction was also found for the Verbal communication (p=.019) and Empathy (p=.023) domains. When splitting the ASDc in subjects with one symptom criterion (ASD 1 ) and those with a ASD, and the FED in subjects with no ASD symptom criteria (FED 0 ) and those with

  2. Growth kinetics, effect of carbon substrate in biosynthesis of mcl-PHA by Pseudomonas putida Bet001

    PubMed Central

    Gumel, A.M.; Annuar, M.S.M.; Heidelberg, T.

    2014-01-01

    Growth associated biosynthesis of medium chain length poly-3-hydroxyalkanoates (mcl-PHA) in Pseudomonas putida Bet001 isolated from palm oil mill effluent was studied. Models with substrate inhibition terms described well the kinetics of its growth. Selected fatty acids (C8:0 to C18:1) and ammonium were used as carbon and nitrogen sources during growth and PHA biosynthesis, resulting in PHA accumulation of about 50 to 69% (w/w) and PHA yields ranging from 10.12 g L−1 to 15.45 g L−1, respectively. The monomer composition of the PHA ranges from C4 to C14, and was strongly influenced by the type of carbon substrate fed. Interestingly, an odd carbon chain length (C7) monomer was also detected when C18:1 was fed. Polymer showed melting temperature (Tm) of 42.0 (± 0.2) °C, glass transition temperature (Tg) of −1.0 (± 0.2) °C and endothermic melting enthalpy of fusion (ΔHf) of 110.3 (± 0.1) J g−1. The molecular weight (Mw) range of the polymer was relatively narrow between 55 to 77 kDa. PMID:25242925

  3. Growth kinetics, effect of carbon substrate in biosynthesis of mcl-PHA by Pseudomonas putida Bet001.

    PubMed

    Gumel, A M; Annuar, M S M; Heidelberg, T

    2014-01-01

    Growth associated biosynthesis of medium chain length poly-3-hydroxyalkanoates (mcl-PHA) in Pseudomonas putida Bet001 isolated from palm oil mill effluent was studied. Models with substrate inhibition terms described well the kinetics of its growth. Selected fatty acids (C8:0 to C18:1) and ammonium were used as carbon and nitrogen sources during growth and PHA biosynthesis, resulting in PHA accumulation of about 50 to 69% (w/w) and PHA yields ranging from 10.12 g L(-1) to 15.45 g L(-1), respectively. The monomer composition of the PHA ranges from C4 to C14, and was strongly influenced by the type of carbon substrate fed. Interestingly, an odd carbon chain length (C7) monomer was also detected when C18:1 was fed. Polymer showed melting temperature (T m) of 42.0 (± 0.2) °C, glass transition temperature (T g) of -1.0 (± 0.2) °C and endothermic melting enthalpy of fusion (ΔHf) of 110.3 (± 0.1) J g(-1). The molecular weight (M w) range of the polymer was relatively narrow between 55 to 77 kDa.

  4. Incorporation of Mg in Free-Standing HVPE GaN Substrates

    NASA Astrophysics Data System (ADS)

    Zvanut, M. E.; Dashdorj, J.; Freitas, J. A.; Glaser, E. R.; Willoughby, W. R.; Leach, J. H.; Udwary, K.

    2016-06-01

    Mg, the only effective p-type dopant for nitrides, is well studied in thin films due to the important role of the impurity in light-emitting diodes and high-power electronics. However, there are few reports of Mg in thick free-standing GaN substrates. Here, we demonstrate successful incorporation of Mg into GaN grown by hydride vapor-phase epitaxy (HVPE) using metallic Mg as the doping source. The concentration of Mg obtained from four separate growth runs ranged between 1016 cm-3 and 1019 cm-3. Raman spectroscopy and x-ray diffraction revealed that Mg did not induce stress or perturb the crystalline quality of the HVPE GaN substrates. Photoluminescence (PL) and electron paramagnetic resonance (EPR) spectroscopies were performed to investigate the types of point defects in the crystals. The near-band-edge excitonic and shallow donor-shallow acceptor radiative recombination processes involving shallow Mg acceptors were prominent in the PL spectrum of a sample doped to 3 × 1018 cm-3, while the EPR signal was also thought to represent a shallow Mg acceptor. Detection of this signal reflects minimization of nonuniform strain obtained in the thick free-standing HVPE GaN compared with heteroepitaxial thin films.

  5. Plasmids of ’Legionella’ Species

    DTIC Science & Technology

    1982-03-09

    Legionella , may acquire transposons which code for drug resistance. In view of the narrow spectrum of antibiotics effective in the treatment of diseases...resistance. In view of the narrow spectrum of antibiotics effective in the treatment of diseases caused by Legionella species, the acquisition of plasmid...by the very narrow spectrum of antibiotics effective in the treatment of the disease. We were interested in examining strains of Legionella for i1

  6. Droplet squeezing through a narrow constriction: Minimum impulse and critical velocity

    NASA Astrophysics Data System (ADS)

    Zhang, Zhifeng; Drapaca, Corina; Chen, Xiaolin; Xu, Jie

    2017-07-01

    Models of a droplet passing through narrow constrictions have wide applications in science and engineering. In this paper, we report our findings on the minimum impulse (momentum change) of pushing a droplet through a narrow circular constriction. The existence of this minimum impulse is mathematically derived and numerically verified. The minimum impulse happens at a critical velocity when the time-averaged Young-Laplace pressure balances the total minor pressure loss in the constriction. Finally, numerical simulations are conducted to verify these concepts. These results could be relevant to problems of energy optimization and studies of chemical and biomedical systems.

  7. Automated cassette-to-cassette substrate handling system

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kraus, Joseph Arthur; Boyer, Jeremy James; Mack, Joseph

    2014-03-18

    An automated cassette-to-cassette substrate handling system includes a cassette storage module for storing a plurality of substrates in cassettes before and after processing. A substrate carrier storage module stores a plurality of substrate carriers. A substrate carrier loading/unloading module loads substrates from the cassette storage module onto the plurality of substrate carriers and unloads substrates from the plurality of substrate carriers to the cassette storage module. A transport mechanism transports the plurality of substrates between the cassette storage module and the plurality of substrate carriers and transports the plurality of substrate carriers between the substrate carrier loading/unloading module and amore » processing chamber. A vision system recognizes recesses in the plurality of substrate carriers corresponding to empty substrate positions in the substrate carrier. A processor receives data from the vision system and instructs the transport mechanism to transport substrates to positions on the substrate carrier in response to the received data.« less

  8. Resting state EEG abnormalities in autism spectrum disorders

    PubMed Central

    2013-01-01

    Autism spectrum disorders (ASD) are a group of complex and heterogeneous developmental disorders involving multiple neural system dysfunctions. In an effort to understand neurophysiological substrates, identify etiopathophysiologically distinct subgroups of patients, and track outcomes of novel treatments with translational biomarkers, EEG (electroencephalography) studies offer a promising research strategy in ASD. Resting-state EEG studies of ASD suggest a U-shaped profile of electrophysiological power alterations, with excessive power in low-frequency and high-frequency bands, abnormal functional connectivity, and enhanced power in the left hemisphere of the brain. In this review, we provide a summary of recent findings, discuss limitations in available research that may contribute to inconsistencies in the literature, and offer suggestions for future research in this area for advancing the understanding of ASD. PMID:24040879

  9. Electronic characterization of defects in narrow gap semiconductors

    NASA Technical Reports Server (NTRS)

    Patterson, James D.

    1993-01-01

    The study of point defects in semiconductors has a long and honorable history. In particular, the detailed understanding of shallow defects in common semiconductors traces back to the classic work of Kohn and Luttinger. However, the study of defects in narrow gap semiconductors represents a much less clear story. Here, both shallow defects (caused by long range potentials) and deep defects (from short range potentials) are far from being completely understood. In this study, all results are calculational and our focus is on the chemical trend of deep levels in narrow gap semiconductors. We study substitutional (including antisite), interstitial and ideal vacancy defects. For substitutional and interstitial impurities, the efects of relaxation are included. For materials like Hg(1-x)Cd(x)Te, we study how the deep levels vary with x, of particular interest is what substitutional and interstitial atoms yield energy levels in the gap i.e. actually produce deep ionized levels. Also, since the main technique utilized is Green's functions, we include some summary of that method.

  10. Comparison of RF spectrum prediction methods for dynamic spectrum access

    NASA Astrophysics Data System (ADS)

    Kovarskiy, Jacob A.; Martone, Anthony F.; Gallagher, Kyle A.; Sherbondy, Kelly D.; Narayanan, Ram M.

    2017-05-01

    Dynamic spectrum access (DSA) refers to the adaptive utilization of today's busy electromagnetic spectrum. Cognitive radio/radar technologies require DSA to intelligently transmit and receive information in changing environments. Predicting radio frequency (RF) activity reduces sensing time and energy consumption for identifying usable spectrum. Typical spectrum prediction methods involve modeling spectral statistics with Hidden Markov Models (HMM) or various neural network structures. HMMs describe the time-varying state probabilities of Markov processes as a dynamic Bayesian network. Neural Networks model biological brain neuron connections to perform a wide range of complex and often non-linear computations. This work compares HMM, Multilayer Perceptron (MLP), and Recurrent Neural Network (RNN) algorithms and their ability to perform RF channel state prediction. Monte Carlo simulations on both measured and simulated spectrum data evaluate the performance of these algorithms. Generalizing spectrum occupancy as an alternating renewal process allows Poisson random variables to generate simulated data while energy detection determines the occupancy state of measured RF spectrum data for testing. The results suggest that neural networks achieve better prediction accuracy and prove more adaptable to changing spectral statistics than HMMs given sufficient training data.

  11. FURTHER CONSTRAINTS ON THE OPTICAL TRANSMISSION SPECTRUM OF HAT-P-1b

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Montalto, M.; Santos, N. C.; Martins, J. H. C.

    We report on novel observations of HAT-P-1 aimed at constraining the optical transmission spectrum of the atmosphere of its transiting hot-Jupiter exoplanet. Ground-based differential spectrophotometry was performed over two transit windows using the DOLORES spectrograph at the Telescopio Nazionale Galileo. Our measurements imply an average planet to star radius ratio equal to R{sub p}/R{sub *} = (0.1159 ± 0.0005). This result is consistent with the value obtained from recent near-infrared measurements of this object, but differs from previously reported optical measurements, being lower by around 4.4 exoplanet scale heights. Analyzing the data over five different spectral bins of ∼600 Åmore » wide, we observed a single peaked spectrum (3.7 σ level) with a blue cutoff corresponding to the blue edge of the broad absorption wing of sodium and an increased absorption in the region in-between 6180 and 7400 Å. We also infer that the width of the broad absorption wings due to alkali metals is likely narrower than the one implied by solar abundance clear atmospheric models. We interpret the result as evidence that HAT-P-1b has a partially clear atmosphere at optical wavelengths with a more modest contribution from an optical absorber than previously reported.« less

  12. Further Constraints on the Optical Transmission Spectrum of HAT-P-1b

    NASA Astrophysics Data System (ADS)

    Montalto, M.; Iro, N.; Santos, N. C.; Desidera, S.; Martins, J. H. C.; Figueira, P.; Alonso, R.

    2015-09-01

    We report on novel observations of HAT-P-1 aimed at constraining the optical transmission spectrum of the atmosphere of its transiting hot-Jupiter exoplanet. Ground-based differential spectrophotometry was performed over two transit windows using the DOLORES spectrograph at the Telescopio Nazionale Galileo. Our measurements imply an average planet to star radius ratio equal to Rp/R* = (0.1159 ± 0.0005). This result is consistent with the value obtained from recent near-infrared measurements of this object, but differs from previously reported optical measurements, being lower by around 4.4 exoplanet scale heights. Analyzing the data over five different spectral bins of ∼600 Å wide, we observed a single peaked spectrum (3.7 σ level) with a blue cutoff corresponding to the blue edge of the broad absorption wing of sodium and an increased absorption in the region in-between 6180 and 7400 Å. We also infer that the width of the broad absorption wings due to alkali metals is likely narrower than the one implied by solar abundance clear atmospheric models. We interpret the result as evidence that HAT-P-1b has a partially clear atmosphere at optical wavelengths with a more modest contribution from an optical absorber than previously reported.

  13. Microsputterer with integrated ion-drag focusing for additive manufacturing of thin, narrow conductive lines

    NASA Astrophysics Data System (ADS)

    Kornbluth, Y. S.; Mathews, R. H.; Parameswaran, L.; Racz, L. M.; Velásquez-García, L. F.

    2018-04-01

    We report the design, modelling, and proof-of-concept demonstration of a continuously fed, atmospheric-pressure microplasma metal sputterer that is capable of printing conductive lines narrower than the width of the target without the need for post-processing or lithographic patterning. Ion drag-induced focusing is harnessed to print narrow lines; the focusing mechanism is modelled via COMSOL Multiphysics simulations and validated with experiments. A microplasma sputter head with gold target is constructed and used to deposit imprints with minimum feature sizes as narrow as 9 µm, roughness as small as 55 nm, and electrical resistivity as low as 1.1 µΩ · m.

  14. Kinetic analysis of extension of substrate specificity with Xanthomonas maltophilia, Aeromonas hydrophila, and Bacillus cereus metallo-beta-lactamases.

    PubMed Central

    Felici, A; Amicosante, G

    1995-01-01

    Twenty beta-lactam molecules, including penicillins, cephalosporins, penems, carbapenems, and monobactams, were investigated as potential substrates for Xanthomonas maltophilia ULA-511, Aeromonas hydrophila AE036, and Bacillus cereus 5/B/6 metallo-beta-lactamases. A detailed analysis of the kinetic parameters examined confirmed these enzymes to be broad-spectrum beta-lactamases with different ranges of catalytic efficiency. Cefoxitin and moxalactam, substrates for the beta-lactamases from X. maltophilia ULA-511 and B. cereus 5/B/6, behaved as inactivators of the A. hydrophila AE036 metallo-beta-lactamase, which appeared to be unique among the enzymes tested in this study. In addition, we report a new, faster, and reliable purification procedure for the B. cereus 5/B/6 metallo-beta-lactamase, cloned in Escherichia coli HB101. PMID:7695305

  15. 17 CFR 41.14 - Transition period for indexes that cease being narrow-based security indexes.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... provision. An index that is a narrow-based security index that becomes a broad-based security index for no...-five days. An index that is a narrow-based security index that becomes a broad-based security index for...

  16. 17 CFR 41.14 - Transition period for indexes that cease being narrow-based security indexes.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... provision. An index that is a narrow-based security index that becomes a broad-based security index for no...-five days. An index that is a narrow-based security index that becomes a broad-based security index for...

  17. 17 CFR 41.14 - Transition period for indexes that cease being narrow-based security indexes.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... provision. An index that is a narrow-based security index that becomes a broad-based security index for no...-five days. An index that is a narrow-based security index that becomes a broad-based security index for...

  18. 17 CFR 41.14 - Transition period for indexes that cease being narrow-based security indexes.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... provision. An index that is a narrow-based security index that becomes a broad-based security index for no...-five days. An index that is a narrow-based security index that becomes a broad-based security index for...

  19. Trunk, head, and step characteristics during normal and narrow-based walking under deteriorated sensory conditions.

    PubMed

    Deshpande, Nandini; Zhang, Fang

    2014-01-01

    The ability to maintain stability in the frontal plane (medialateral direction) while walking is commonly included as a component of motor performance assessment. Postural control in the frontal plane may deteriorate faster and earlier with increasing age, compared to that in the sagittal plane (anteroposterior direction). Fifteen young (20-30 years old) and 15 older (>65 years old) healthy participants were recruited to investigate age-related differences in postural control during the normal and narrow-based walking when performed under suboptimal vestibular and lower limb somatosensory conditions achieved by galvanic stimulation and compliant surfaces, respectively. Gait speed decreased in the narrow-based walking condition, with larger decrease in the elderly (by 6%). In the elderly head roll increased with perturbed vestibular information in impaired somatosensory condition (by 40.70%). In both age groups trunk roll increased under impaired somatosensation in the narrow-based walking condition (by 43.62%) but not in normal walking condition. Older participants adopted a more cautious strategy characterized by lower walking speed when walking on a narrow base and exhibited deteriorated integrative ability of the CNS for head control. Accurate lower limb somatosensation may play a critical role in narrow-based walking.

  20. SBS 0846+513: a New Gamma-ray Emitting Narrow-line Seyfert 1 Galaxy

    NASA Technical Reports Server (NTRS)

    D'Ammando, F.; Orienti, M.; Finke, J.; Raiteri, C. M.; Angelakis, E.; Fuhrmann, L.; Giroletti, M.; Hovatta, T.; Max-Moerbeck, W.; Perkins, J. S.; hide

    2012-01-01

    We report Fermi-LAT observations of the radio-loud AGN SBS 0846+513 (z=0.5835), optically classified as a Narrow-Line Seyfert 1 galaxy, together with new and archival radio-to-X-ray data. The source was not active at ?-ray energies during the first two years of Fermi operation. A significant increase in activity was observed during 2010 October-2011 August. In particular a strong gamma-ray flare was observed in 2011 June reaching an isotropic ?-ray luminosity (0.1-300 GeV) of 1.0×10(sup 48) erg s(sup -1), comparable to that of the brightest flat spectrum radio quasars, and showing spectral evolution in gamma rays. An apparent superluminal velocity of (8.2+/-1.5)c in the jet was inferred from 2011-2012 VLBA images, suggesting the presence of a highly relativistic jet. Both the power released by this object during the flaring activity and the apparent superluminal velocity are strong indications of the presence of a relativistic jet as powerful as those of blazars. In addition, variability and spectral properties in radio and gamma-ray bands indicate blazar-like behaviour, suggesting that, except for some distinct optical characteristics, SBS 0846+513 could be considered as a young blazar at the low end of the blazar's black hole mass distribution.

  1. Qualification of submerged-arc narrow strip cladding process

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ayres, P.S.; Gottschling, J.D.; Jeffers, G.K.

    1975-08-01

    An unique narrow strip cladding process for use on both plate and forging material for nuclear components was developed. The qualification testing of this low-heat input process for cladding nuclear components, including those of SA508 Class 2 material is described. The theory that explains the acceptable results of these tests is also given. (auth)

  2. Qualification of submerged-arc narrow strip cladding process

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ayres, P.S.; Gottschling, J.D.; Jeffers, G.K.

    1976-03-01

    Babcock and Wilcox has developed an unique narrow strip cladding process for use on both plate and forging material for nuclear components. The qualification testing of this low-heat input process for cladding nuclear components is described, including those of SA508 Class 2 material. The theory that explains the acceptable results of these tests is also given.

  3. Period Effects, Cohort Effects, and the Narrowing Gender Wage Gap

    PubMed Central

    Campbell, Colin; Pearlman, Jessica

    2015-01-01

    Despite the abundance of sociological research on the gender wage gap, questions remain. In particular, the role of cohorts is under investigated. Using data from the Current Population Survey, we use Age-Period-Cohort analysis to uniquely estimate age, period, and cohort effects on the gender wage gap. The narrowing of the gender wage gap that occurred between 1975 and 2009 is largely due to cohort effects. Since the mid-1990s, the gender wage gap has continued to close absent of period effects. While gains in female wages contributed to declines in the gender wage gap for cohorts born before 1950, for later cohorts the narrowing of the gender wage gap is primarily a result of declines in male wages. PMID:24090861

  4. Vibration-tolerant narrow-linewidth semiconductor disk laser using novel frequency-stabilisation schemes

    NASA Astrophysics Data System (ADS)

    Hunter, Craig R.; Jones, Brynmor E.; Schlosser, Peter; Sørensen, Simon Toft; Strain, Michael J.; McKnight, Loyd J.

    2018-02-01

    This paper will present developments in narrow-linewidth semiconductor-disk-laser systems using novel frequencystabilisation schemes for reduced sensitivity to mechanical vibrations, a critical requirement for mobile applications. Narrow-linewidth single-frequency lasers are required for a range of applications including metrology and highresolution spectroscopy. Stabilisation of the laser was achieved using a monolithic fibre-optic ring resonator with free spectral range of 181 MHz and finesse of 52 to act as passive reference cavity for the laser. Such a cavity can operate over a broad wavelength range and is immune to a wide band of vibrational frequency noise due to its monolithic implementation. The frequency noise of the locked system has been measured and compared to typical Fabry-Perotlocked lasers using vibration equipment to simulate harsh environments, and analysed here. Locked linewidths of < 40 kHz have been achieved. These developments offer a portable, narrow-linewidth laser system for harsh environments that can be flexibly designed for a range of applications.

  5. Atomic Dynamics in Simple Liquid: de Gennes Narrowing Revisited

    DOE PAGES

    Wu, Bin; Iwashita, Takuya; Egami, Takeshi

    2018-03-27

    The de Gennes narrowing phenomenon is frequently observed by neutron or x-ray scattering measurements of the dynamics of complex systems, such as liquids, proteins, colloids, and polymers. The characteristic slowing down of dynamics in the vicinity of the maximum of the total scattering intensity is commonly attributed to enhanced cooperativity. In this Letter, we present an alternative view on its origin through the examination of the time-dependent pair correlation function, the van Hove correlation function, for a model liquid in two, three, and four dimensions. We find that the relaxation time increases monotonically with distance and the dependence on distancemore » varies with dimension. We propose a heuristic explanation of this dependence based on a simple geometrical model. Furthermore, this finding sheds new light on the interpretation of the de Gennes narrowing phenomenon and the α-relaxation time.« less

  6. Atomic Dynamics in Simple Liquid: de Gennes Narrowing Revisited

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wu, Bin; Iwashita, Takuya; Egami, Takeshi

    The de Gennes narrowing phenomenon is frequently observed by neutron or x-ray scattering measurements of the dynamics of complex systems, such as liquids, proteins, colloids, and polymers. The characteristic slowing down of dynamics in the vicinity of the maximum of the total scattering intensity is commonly attributed to enhanced cooperativity. In this Letter, we present an alternative view on its origin through the examination of the time-dependent pair correlation function, the van Hove correlation function, for a model liquid in two, three, and four dimensions. We find that the relaxation time increases monotonically with distance and the dependence on distancemore » varies with dimension. We propose a heuristic explanation of this dependence based on a simple geometrical model. Furthermore, this finding sheds new light on the interpretation of the de Gennes narrowing phenomenon and the α-relaxation time.« less

  7. Ultra-narrow pulse generator with precision-adjustable pulse width

    NASA Astrophysics Data System (ADS)

    Fu, Zaiming; Liu, Hanglin

    2018-05-01

    In this paper, a novel ultra-narrow pulse generation approach is proposed. It is based on the decomposition and synthesis of pulse edges. Through controlling their relative delay, an ultra-narrow pulse could be generated. By employing field programmable gate array digital synthesis technology, the implemented pulse generator is with programmable ability. The amplitude of pulse signals is controlled by the radio frequency amplifiers and bias tees, and high precision can be achieved. More importantly, the proposed approach can break through the limitation of device's propagation delay and optimize the resolution and the accuracy of the pulse width significantly. The implemented pulse generator has two channels, whose minimum pulse width, frequency range, and amplitude range are 100 ps, 15 MHz-1.5 GHz, and 0.1 Vpp-1.8 Vpp, respectively. Both resolution of pulse width and channel delay are 1 ps, and amplitude resolution is 10 mVpp.

  8. Carbon nanotube substrates and catalyzed hot stamp for polishing and patterning the substrates

    DOEpatents

    Wang, Yuhuang [Evanston, IL; Hauge, Robert H [Houston, TX; Schmidt, Howard K [Houston, TX; Kim, Myung Jong [Houston, TX; Kittrell, W Carter [Houston, TX

    2009-09-08

    The present invention is generally directed to catalyzed hot stamp methods for polishing and/or patterning carbon nanotube-containing substrates. In some embodiments, the substrate, as a carbon nanotube fiber end, is brought into contact with a hot stamp (typically at 200-800.degree. C.), and is kept in contact with the hot stamp until the morphology/patterns on the hot stamp have been transferred to the substrate. In some embodiments, the hot stamp is made of material comprising one or more transition metals (Fe, Ni, Co, Pt, Ag, Au, etc.), which can catalyze the etching reaction of carbon with H.sub.2, CO.sub.2, H.sub.2O, and/or O.sub.2. Such methods can (1) polish the carbon nanotube-containing substrate with a microscopically smooth finish, and/or (2) transfer pre-defined patterns from the hot stamp to the substrate. Such polished or patterned carbon nanotube substrates can find application as carbon nanotube electrodes, field emitters, and field emitter arrays for displays and electron sources.

  9. Search for Narrow Resonances in the b-Tagged Dijet Mass Spectrum in Proton-Proton Collisions at sqrt[s]=8  TeV.

    PubMed

    Sirunyan, A M; Tumasyan, A; Adam, W; Ambrogi, F; Asilar, E; Bergauer, T; Brandstetter, J; Brondolin, E; Dragicevic, M; Erö, J; Escalante Del Valle, A; Flechl, M; Friedl, M; Frühwirth, R; Ghete, V M; Grossmann, J; Hrubec, J; Jeitler, M; König, A; Krammer, N; Krätschmer, I; Liko, D; Madlener, T; Mikulec, I; Pree, E; Rad, N; Rohringer, H; Schieck, J; Schöfbeck, R; Spanring, M; Spitzbart, D; Taurok, A; Waltenberger, W; Wittmann, J; Wulz, C-E; Zarucki, M; Chekhovsky, V; Mossolov, V; Suarez Gonzalez, J; De Wolf, E A; Di Croce, D; Janssen, X; Lauwers, J; Pieters, M; Van De Klundert, M; Van Haevermaet, H; Van Mechelen, P; Van Remortel, N; Abu Zeid, S; Blekman, F; D'Hondt, J; De Bruyn, I; De Clercq, J; Deroover, K; Flouris, G; Lontkovskyi, D; Lowette, S; Marchesini, I; Moortgat, S; Moreels, L; Python, Q; Skovpen, K; Tavernier, S; Van Doninck, W; Van Mulders, P; Van Parijs, I; Beghin, D; Bilin, B; Brun, H; Clerbaux, B; De Lentdecker, G; Delannoy, H; Dorney, B; Fasanella, G; Favart, L; Goldouzian, R; 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Erdmann, W; Horisberger, R; Ingram, Q; Kaestli, H C; Kotlinski, D; Langenegger, U; Rohe, T; Wiederkehr, S A; Backhaus, M; Bäni, L; Berger, P; Casal, B; Chernyavskaya, N; Dissertori, G; Dittmar, M; Donegà, M; Dorfer, C; Grab, C; Heidegger, C; Hits, D; Hoss, J; Klijnsma, T; Lustermann, W; Marionneau, M; Meinhard, M T; Meister, D; Micheli, F; Musella, P; Nessi-Tedaldi, F; Pata, J; Pauss, F; Perrin, G; Perrozzi, L; Quittnat, M; Reichmann, M; Ruini, D; Sanz Becerra, D A; Schönenberger, M; Shchutska, L; Tavolaro, V R; Theofilatos, K; Vesterbacka Olsson, M L; Wallny, R; Zhu, D H; Aarrestad, T K; Amsler, C; Brzhechko, D; Canelli, M F; De Cosa, A; Del Burgo, R; Donato, S; Galloni, C; Hreus, T; Kilminster, B; Neutelings, I; Pinna, D; Rauco, G; Robmann, P; Salerno, D; Schweiger, K; Seitz, C; Takahashi, Y; Zucchetta, A; Candelise, V; Chang, Y H; Cheng, K Y; Doan, T H; Jain, Sh; Khurana, R; Kuo, C M; Lin, W; Pozdnyakov, A; Yu, S S; Kumar, Arun; Chang, P; Chao, Y; Chen, K F; Chen, P H; Fiori, F; Hou, W-S; Hsiung, Y; Liu, Y F; Lu, R-S; Paganis, E; Psallidas, A; Steen, A; Tsai, J F; Asavapibhop, B; Kovitanggoon, K; Singh, G; Srimanobhas, N; Bat, A; Boran, F; Cerci, S; Damarseckin, S; Demiroglu, Z S; Dozen, C; Dumanoglu, I; Girgis, S; Gokbulut, G; Guler, Y; Hos, I; Kangal, E E; Kara, O; Kiminsu, U; Oglakci, M; Onengut, G; Ozdemir, K; Sunar Cerci, D; Tali, B; Tok, U G; Topakli, H; Turkcapar, S; Zorbakir, I S; Zorbilmez, C; Karapinar, G; Ocalan, K; Yalvac, M; Zeyrek, M; Atakisi, I O; Gülmez, E; Kaya, M; Kaya, O; Tekten, S; Yetkin, E A; Agaras, M N; Atay, S; Cakir, A; Cankocak, K; Komurcu, Y; Grynyov, B; Levchuk, L; Ball, F; Beck, L; Brooke, J J; Burns, D; Clement, E; Cussans, D; Davignon, O; Flacher, H; Goldstein, J; Heath, G P; Heath, H F; Kreczko, L; Newbold, D M; Paramesvaran, S; Sakuma, T; Seif El Nasr-Storey, S; Smith, D; Smith, V J; Bell, K W; Belyaev, A; Brew, C; Brown, R M; Cieri, D; Cockerill, D J A; Coughlan, J A; Harder, K; Harper, S; Linacre, J; Olaiya, E; Petyt, D; Shepherd-Themistocleous, C H; 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Sharma, V; Simon, S; Tadel, M; Vartak, A; Wasserbaech, S; Wood, J; Würthwein, F; Yagil, A; Zevi Della Porta, G; Amin, N; Bhandari, R; Bradmiller-Feld, J; Campagnari, C; Citron, M; Dishaw, A; Dutta, V; Franco Sevilla, M; Gouskos, L; Heller, R; Incandela, J; Ovcharova, A; Qu, H; Richman, J; Stuart, D; Suarez, I; Yoo, J; Anderson, D; Bornheim, A; Bunn, J; Lawhorn, J M; Newman, H B; Nguyen, T Q; Pena, C; Spiropulu, M; Vlimant, J R; Wilkinson, R; Xie, S; Zhang, Z; Zhu, R Y; Andrews, M B; Ferguson, T; Mudholkar, T; Paulini, M; Russ, J; Sun, M; Vogel, H; Vorobiev, I; Weinberg, M; Cumalat, J P; Ford, W T; Jensen, F; Johnson, A; Krohn, M; Leontsinis, S; MacDonald, E; Mulholland, T; Stenson, K; Ulmer, K A; Wagner, S R; Alexander, J; Chaves, J; Cheng, Y; Chu, J; Datta, A; Mcdermott, K; Mirman, N; Patterson, J R; Quach, D; Rinkevicius, A; Ryd, A; Skinnari, L; Soffi, L; Tan, S M; Tao, Z; Thom, J; Tucker, J; Wittich, P; Zientek, M; Abdullin, S; Albrow, M; Alyari, M; Apollinari, G; Apresyan, A; Apyan, A; Banerjee, S; Bauerdick, L A T; Beretvas, A; Berryhill, J; Bhat, P C; Bolla, G; Burkett, K; Butler, J N; Canepa, A; Cerati, G B; Cheung, H W K; Chlebana, F; Cremonesi, M; Duarte, J; Elvira, V D; Freeman, J; Gecse, Z; Gottschalk, E; Gray, L; Green, D; Grünendahl, S; Gutsche, O; Hanlon, J; Harris, R M; Hasegawa, S; Hirschauer, J; Hu, Z; Jayatilaka, B; Jindariani, S; Johnson, M; Joshi, U; Klima, B; Kortelainen, M J; Kreis, B; Lammel, S; Lincoln, D; Lipton, R; Liu, M; Liu, T; Lopes De Sá, R; Lykken, J; Maeshima, K; Magini, N; Marraffino, J M; Mason, D; McBride, P; Merkel, P; Mrenna, S; Nahn, S; O'Dell, V; Pedro, K; Prokofyev, O; Rakness, G; Ristori, L; Savoy-Navarro, A; Schneider, B; Sexton-Kennedy, E; Soha, A; Spalding, W J; Spiegel, L; Stoynev, S; Strait, J; Strobbe, N; Taylor, L; Tkaczyk, S; Tran, N V; Uplegger, L; Vaandering, E W; Vernieri, C; Verzocchi, M; Vidal, R; Wang, M; Weber, H A; Whitbeck, A; Wu, W; Acosta, D; Avery, P; Bortignon, P; Bourilkov, D; Brinkerhoff, A; Carnes, A; Carver, M; Curry, D; Field, R D; Furic, I K; Gleyzer, S V; Joshi, B M; Konigsberg, J; Korytov, A; Kotov, K; Ma, P; Matchev, K; Mei, H; Mitselmakher, G; Shi, K; Sperka, D; Terentyev, N; Thomas, L; Wang, J; Wang, S; Yelton, J; Joshi, Y R; Linn, S; Markowitz, P; Rodriguez, J L; Ackert, A; Adams, T; Askew, A; Hagopian, S; Hagopian, V; Johnson, K F; Kolberg, T; Martinez, G; Perry, T; Prosper, H; Saha, A; Santra, A; Sharma, V; Yohay, R; Baarmand, M M; Bhopatkar, V; Colafranceschi, S; Hohlmann, M; Noonan, D; Roy, T; Yumiceva, F; Adams, M R; Apanasevich, L; Berry, D; Betts, R R; Cavanaugh, R; Chen, X; Dittmer, S; Evdokimov, O; Gerber, C E; Hangal, D A; Hofman, D J; Jung, K; Kamin, J; Sandoval Gonzalez, I D; Tonjes, M B; Varelas, N; Wang, H; Wu, Z; Zhang, J; Bilki, B; Clarida, W; Dilsiz, K; Durgut, S; Gandrajula, R P; Haytmyradov, M; Khristenko, V; Merlo, J-P; Mermerkaya, H; Mestvirishvili, A; Moeller, A; Nachtman, J; Ogul, H; Onel, Y; Ozok, F; Penzo, A; Snyder, C; Tiras, E; Wetzel, J; Yi, K; Blumenfeld, B; 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Roland, C; Roland, G; Stephans, G S F; Sumorok, K; Tatar, K; Velicanu, D; Wang, J; Wang, T W; Wyslouch, B; Zhaozhong, S; Benvenuti, A C; Chatterjee, R M; Evans, A; Hansen, P; Kalafut, S; Kubota, Y; Lesko, Z; Mans, J; Nourbakhsh, S; Ruckstuhl, N; Rusack, R; Turkewitz, J; Wadud, M A; Acosta, J G; Oliveros, S; Avdeeva, E; Bloom, K; Claes, D R; Fangmeier, C; Golf, F; Gonzalez Suarez, R; Kamalieddin, R; Kravchenko, I; Monroy, J; Siado, J E; Snow, G R; Stieger, B; Godshalk, A; Harrington, C; Iashvili, I; Nguyen, D; Parker, A; Rappoccio, S; Roozbahani, B; Alverson, G; Barberis, E; Freer, C; Hortiangtham, A; Massironi, A; Morse, D M; Orimoto, T; Teixeira De Lima, R; Wamorkar, T; Wang, B; Wisecarver, A; Wood, D; Bhattacharya, S; Charaf, O; Hahn, K A; Mucia, N; Odell, N; Schmitt, M H; Sung, K; Trovato, M; Velasco, M; Bucci, R; Dev, N; Hildreth, M; Hurtado Anampa, K; Jessop, C; Karmgard, D J; Kellams, N; Lannon, K; Li, W; Loukas, N; Marinelli, N; Meng, F; Mueller, C; Musienko, Y; Planer, M; Reinsvold, A; Ruchti, R; Siddireddy, P; Smith, G; Taroni, S; Wayne, M; Wightman, A; Wolf, M; Woodard, A; Alimena, J; Antonelli, L; Bylsma, B; Durkin, L S; Flowers, S; Francis, B; Hart, A; Hill, C; Ji, W; Ling, T Y; Luo, W; Winer, B L; Wulsin, H W; Cooperstein, S; Driga, O; Elmer, P; Hardenbrook, J; Hebda, P; Higginbotham, S; Kalogeropoulos, A; Lange, D; Luo, J; Marlow, D; Mei, K; Ojalvo, I; Olsen, J; Palmer, C; Piroué, P; Salfeld-Nebgen, J; Stickland, D; Tully, C; Malik, S; Norberg, S; Barker, A; Barnes, V E; Das, S; Gutay, L; Jones, M; Jung, A W; Khatiwada, A; Miller, D H; Neumeister, N; Peng, C C; Qiu, H; Schulte, J F; Sun, J; Wang, F; Xiao, R; Xie, W; Cheng, T; Dolen, J; Parashar, N; Chen, Z; Ecklund, K M; Freed, S; Geurts, F J M; Guilbaud, M; Kilpatrick, M; Li, W; Michlin, B; Padley, B P; Roberts, J; Rorie, J; Shi, W; Tu, Z; Zabel, J; Zhang, A; Bodek, A; de Barbaro, P; Demina, R; Duh, Y T; Ferbel, T; Galanti, M; Garcia-Bellido, A; Han, J; Hindrichs, O; Khukhunaishvili, A; Lo, K H; Tan, P; Verzetti, M; Ciesielski, R; Goulianos, K; Mesropian, C; Agapitos, A; Chou, J P; Gershtein, Y; Gómez Espinosa, T A; Halkiadakis, E; Heindl, M; Hughes, E; Kaplan, S; Kunnawalkam Elayavalli, R; Kyriacou, S; Lath, A; Montalvo, R; Nash, K; Osherson, M; Saka, H; Salur, S; Schnetzer, S; Sheffield, D; Somalwar, S; Stone, R; Thomas, S; Thomassen, P; Walker, M; Delannoy, A G; Heideman, J; Riley, G; Rose, K; Spanier, S; Thapa, K; Bouhali, O; Castaneda Hernandez, A; Celik, A; Dalchenko, M; De Mattia, M; Delgado, A; Dildick, S; Eusebi, R; Gilmore, J; Huang, T; Kamon, T; Mueller, R; Pakhotin, Y; Patel, R; Perloff, A; Perniè, L; Rathjens, D; Safonov, A; Tatarinov, A; Akchurin, N; Damgov, J; De Guio, F; Dudero, P R; Faulkner, J; Gurpinar, E; Kunori, S; Lamichhane, K; Lee, S W; Mengke, T; Muthumuni, S; Peltola, T; Undleeb, S; Volobouev, I; Wang, Z; Greene, S; Gurrola, A; Janjam, R; Johns, W; Maguire, C; Melo, A; Ni, H; Padeken, K; Ruiz Alvarez, J D; Sheldon, P; Tuo, S; Velkovska, J; Xu, Q; Arenton, M W; Barria, P; Cox, B; Hirosky, R; Joyce, M; Ledovskoy, A; Li, H; Neu, C; Sinthuprasith, T; Wang, Y; Wolfe, E; Xia, F; Harr, R; Karchin, P E; Poudyal, N; Sturdy, J; Thapa, P; Zaleski, S; Brodski, M; Buchanan, J; Caillol, C; Carlsmith, D; Dasu, S; Dodd, L; Duric, S; Gomber, B; Grothe, M; Herndon, M; Hervé, A; Hussain, U; Klabbers, P; Lanaro, A; Levine, A; Long, K; Loveless, R; Rekovic, V; Ruggles, T; Savin, A; Smith, N; Smith, W H; Woods, N

    2018-05-18

    A search for narrow resonances decaying to bottom quark-antiquark pairs is presented, using a data sample of proton-proton collisions at sqrt[s]=8  TeV corresponding to an integrated luminosity of 19.7  fb^{-1}. The search is extended to masses lower than those reached in typical searches for resonances decaying into jet pairs at the LHC, by taking advantage of triggers that identify jets originating from bottom quarks. No significant excess of events is observed above the background predictions. Limits are set on the product of cross section and branching fraction to bottom quarks for spin 0, 1, and 2 resonances in the mass range of 325-1200 GeV. These results improve on the limits for resonances decaying into jet pairs in the 325-500 GeV mass range.

  10. Narrow Radiative Recombination Continua: A Signature of Ions Crossing the Contact Discontinuity of Astrophysical Shocks

    NASA Technical Reports Server (NTRS)

    Behar, Ehud; Nordon, Raanan; Soker, Noam; Kastner, Joel H.; Yu, Young Sam

    2009-01-01

    X-rays from planetary nebulae (PNs) are believed to originate from a shock driven into the fast stellar wind (v 1000 kilometers per second) as it collides with an earlier circumstellar slow wind (v 10 kilometers per second). In theory, the shocked fast wind (hot hubble) and the ambient cold nebula can remain separated by magnetic fields along a surface referred to as the contact discontinuity (CD) that inhibits diffusion and heat conduction. The CD region is extremely difficult to probe directly owing to its small size and faint emission. This has largely left the study of CDs, stellar-shocks, and the associated micro-physics in the realm of theory. This paper presents spectroscopic evidence for ions from the hot bubble (kT approximately equal to 100 eV) crossing the CD and penetrating the cold nebular gas (kT approximately equal to 1 eV). Specifically, a narrow radiative recombination continuum (RRC) emission feature is identified in the high resolution X-ray spectrum of the PN BD+30degree3639 indicating bare C VII ions are recombining with cool electrons at kT(sub e) = 1.7 plus or minus 1.3 eV. An upper limit to the flux of the narrow RRC of H-like C VI is obtained as well. The RRCs are interpreted as due to C ions from the hot bubble of BD+30degree3639 crossing the CD into the cold nebula, where they ultimately recombine with its cool electrons. The RRC flux ratio of C VII to C VI constrains the temperature jump across the CD to deltakT greater than 80 eV, providing for the first time direct evidence for the stark temperature disparity between the two sides of an astrophysical CD, and constraining the role of magnetic fields and heat conduction accordingly. Two colliding-wind binaries are noted to have similar RRCs suggesting a temperature jump and CD crossing by ions may be common feature of stellar wind shocks.

  11. Reflectance spectrum of plasmon waveguide interband cascade lasers and observation of the Berreman effect

    NASA Astrophysics Data System (ADS)

    Hinkey, Robert T.; Tian, Zhaobing; Yang, Rui Q.; Mishima, Tetsuya D.; Santos, Michael B.

    2011-08-01

    Noninvasive infrared reflectance measurements have been explored as a method for studying the optical properties of Si-doped cladding layers of plasmon waveguide interband cascade lasers. Measurements and theoretical simulations of the reflectance spectra were carried out on both the laser structures themselves, as well as highly doped InAs films grown on GaAs substrates. We have found that there is a sharp drop in the signal of the reflectance spectrum for p-polarized light oscillating near the plasma frequency. This is a manifestation of the so-called Berreman effect, which occurs at frequencies where the dielectric function approaches zero. This is distinct from the plasma edge feature seen in the reflectance spectrum of thick samples. The plasma frequencies of the highly doped layers were obtained by identifying the Berreman feature in the measured spectrum and fitting the spectrum to a modeled curve. Using a model for the effective mass, we were able to obtain measurements of the conduction electron concentration (in a range from 1018 to 1019 cm-3) in the waveguide cladding layers with values that were in good agreement with those found using Hall effect and SIMS measurements. The reflectance data was effectively used to achieve better calibration of the Si-doping during the growth of the n++-type InAs layers in the plasmon waveguide laser structures.

  12. Superhydrophobic Ag decorated ZnO nanostructured thin film as effective surface enhanced Raman scattering substrates

    NASA Astrophysics Data System (ADS)

    Jayram, Naidu Dhanpal; Sonia, S.; Poongodi, S.; Kumar, P. Suresh; Masuda, Yoshitake; Mangalaraj, D.; Ponpandian, N.; Viswanathan, C.

    2015-11-01

    The present work is an attempt to overcome the challenges in the fabrication of super hydrophobic silver decorated zinc oxide (ZnO) nanostructure thin films via thermal evaporation process. The ZnO nanowire thin films are prepared without any surface modification and show super hydrophobic nature with a contact angle of 163°. Silver is further deposited onto the ZnO nanowire to obtain nanoworm morphology. Silver decorated ZnO (Ag@ZnO) thin films are used as substrates for surface enhanced Raman spectroscopy (SERS) studies. The formation of randomly arranged nanowire and silver decorated nanoworm structure is confirmed using FESEM, HR-TEM and AFM analysis. Crystallinity and existence of Ag on ZnO are confirmed using XRD and XPS studies. A detailed growth mechanism is discussed for the formation of the nanowires from nanobeads based on various deposition times. The prepared SERS substrate reveals a reproducible enhancement of 3.082 × 107 M for Rhodamine 6G dye (R6G) for 10-10 molar concentration per liter. A higher order of SERS spectra is obtained for a contact angle of 155°. Thus the obtained thin films show the superhydrophobic nature with a highly enhanced Raman spectrum and act as SERS substrates. The present nanoworm morphology shows a new pathway for the construction of semiconductor thin films for plasmonic studies and challenges the orderly arranged ZnO nanorods, wires and other nano structure substrates used in SERS studies.

  13. Fiber-distributed Ultra-wideband noise radar with steerable power spectrum and colorless base station.

    PubMed

    Zheng, Jianyu; Wang, Hui; Fu, Jianbin; Wei, Li; Pan, Shilong; Wang, Lixian; Liu, Jianguo; Zhu, Ninghua

    2014-03-10

    A fiber-distributed Ultra-wideband (UWB) noise radar was achieved, which consists of a chaotic UWB noise source based on optoelectronic oscillator (OEO), a fiber-distributed transmission link, a colorless base station (BS), and a cross-correlation processing module. Due to a polarization modulation based microwave photonic filter and an electrical UWB pass-band filter embedded in the feedback loop of the OEO, the power spectrum of chaotic UWB signal could be shaped and notch-filtered to avoid the spectrum-overlay-induced interference to the narrow band signals. Meanwhile, the wavelength-reusing could be implemented in the BS by means of the distributed polarization modulation-to-intensity modulation conversion. The experimental comparison for range finding was carried out as the chaotic UWB signal was notch-filtered at 5.2 GHz and 7.8 GHz or not. Measured results indicate that space resolution with cm-level could be realized after 3-km fiber transmission thanks to the excellent self-correlation property of the UWB noise signal provided by the OEO. The performance deterioration of the radar raised by the energy loss of the notch-filtered noise signal was negligible.

  14. Line Narrowing Parameter Measurement by Modulation Spectroscopy

    NASA Technical Reports Server (NTRS)

    Dharamsi, Amin N.

    1998-01-01

    Accurate Characterization of Oxygen A-Band Line Parameters by Wavelength Modulation Spectroscopy with tunable diode lasers is an ongoing research at Old Dominion University, under sponsorship from NASA Langley research Center. The work proposed here will be undertaken under the guidance of Dr. William Chu and Dr. Lamont Poole of the Aerosol Research Branch at NASA Langley-Research Center in Hampton, Virginia. The research was started about two years ago and utilizes wavelength modulation absorption spectroscopy with higher harmonic detection, a technique that we developed at Old Dominion University, to obtain the absorption line characteristics of the Oxygen A-band rovibronic lines. Accurate characterization of this absorption band is needed for processing of data that will be obtained in experiments such as the NASA Stratospheric Aerosol and Gas Experiment III (SAGE III) as part of the US Mission to Planet Earth. The research work for Summer Fellowship undertook a measurement of the Dicke line-narrowing parameters of the Oxygen A-Band lines by using wavelength modulation spectroscopy. Our previous theoretical results had indicated that such a measurement could be done sensitively and in a convenient fashion by using this type of spectroscopy. In particular, theoretical results had indicated that the signal magnitude would depend on pressure in a manner that was very sensitive to the narrowing parameter. One of the major tasks undertaken during the summer of 1998 was to establish experimentally that these theoretical predictions were correct. This was done successfully and the results of the work are being prepared for publication. Experimental Results were obtained in which the magnitude of the signal was measured as a function of pressure, for various harmonic detection orders (N = 1, 2, 3, 4, 5). A comparison with theoretical results was made, and it was shown that the agreement between theory and experiment was very good. More importantly, however, it was shown

  15. Probing dark energy using convergence power spectrum and bi-spectrum

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dinda, Bikash R., E-mail: bikash@ctp-jamia.res.in

    Weak lensing convergence statistics is a powerful tool to probe dark energy. Dark energy plays an important role to the structure formation and the effects can be detected through the convergence power spectrum, bi-spectrum etc. One of the most promising and simplest dark energy model is the ΛCDM . However, it is worth investigating different dark energy models with evolving equation of state of the dark energy. In this work, detectability of different dark energy models from ΛCDM model has been explored through convergence power spectrum and bi-spectrum.

  16. Electrocardiogram artifact caused by rigors mimicking narrow complex tachycardia: a case report.

    PubMed

    Matthias, Anne Thushara; Indrakumar, Jegarajah

    2014-02-04

    The electrocardiogram (ECG) is useful in the diagnosis of cardiac and non-cardiac conditions. Rigors due to shivering can cause electrocardiogram artifacts mimicking various cardiac rhythm abnormalities. We describe an 80-year-old Sri Lankan man with an abnormal electrocardiogram mimicking narrow complex tachycardia during the immediate post-operative period. Electrocardiogram changes caused by muscle tremor during rigors could mimic a narrow complex tachycardia. Identification of muscle tremor as a cause of electrocardiogram artifact can avoid unnecessary pharmacological and non-pharmacological intervention to prevent arrhythmias.

  17. A Narrow-Linewidth Atomic Line Filter for Free Space Quantum Key Distribution under Daytime Atmospheric Conditions

    NASA Astrophysics Data System (ADS)

    Brown, Justin; Woolf, David; Hensley, Joel

    2016-05-01

    Quantum key distribution can provide secure optical data links using the established BB84 protocol, though solar backgrounds severely limit the performance through free space. Several approaches to reduce the solar background include time-gating the photon signal, limiting the field of view through geometrical design of the optical system, and spectral rejection using interference filters. Despite optimization of these parameters, the solar background continues to dominate under daytime atmospheric conditions. We demonstrate an improved spectral filter by replacing the interference filter (Δν ~ 50 GHz) with an atomic line filter (Δν ~ 1 GHz) based on optical rotation of linearly polarized light through a warm Rb vapor. By controlling the magnetic field and the optical depth of the vapor, a spectrally narrow region can be transmitted between crossed polarizers. We find that the transmission is more complex than a single peak and evaluate peak transmission as well as a ratio of peak transmission to average transmission of the local spectrum. We compare filters containing a natural abundance of Rb with those containing isotopically pure 87 Rb and 85 Rb. A filter providing > 95 % transmission and Δν ~ 1.1 GHz is achieved.

  18. Practical applications of the bioinformatics toolbox for narrowing quantitative trait loci.

    PubMed

    Burgess-Herbert, Sarah L; Cox, Allison; Tsaih, Shirng-Wern; Paigen, Beverly

    2008-12-01

    Dissecting the genes involved in complex traits can be confounded by multiple factors, including extensive epistatic interactions among genes, the involvement of epigenetic regulators, and the variable expressivity of traits. Although quantitative trait locus (QTL) analysis has been a powerful tool for localizing the chromosomal regions underlying complex traits, systematically identifying the causal genes remains challenging. Here, through its application to plasma levels of high-density lipoprotein cholesterol (HDL) in mice, we demonstrate a strategy for narrowing QTL that utilizes comparative genomics and bioinformatics techniques. We show how QTL detected in multiple crosses are subjected to both combined cross analysis and haplotype block analysis; how QTL from one species are mapped to the concordant regions in another species; and how genomewide scans associating haplotype groups with their phenotypes can be used to prioritize the narrowed regions. Then we illustrate how these individual methods for narrowing QTL can be systematically integrated for mouse chromosomes 12 and 15, resulting in a significantly reduced number of candidate genes, often from hundreds to <10. Finally, we give an example of how additional bioinformatics resources can be combined with experiments to determine the most likely quantitative trait genes.

  19. Searching for Variability of NV Intrinsic Narrow Absorption Line Systems

    NASA Astrophysics Data System (ADS)

    Rodruck, Michael; Charlton, Jane; Ganguly, Rajib

    2018-01-01

    The majority of quasar absorption line systems with NV detected are found within the associated region (within 5000 km/s of the quasar redshift) and many/most are believed to be related to the quasar accretion disk wind or outflows. The most definite evidence that these NV absorbers are "intrinsic" is partial covering of the quasar continuum source and/or broad line region. Over 75 quasars containing NV narrow absorption lines have observations obtained at different times with the Keck/HIRES and the VLT/UVES spectrographs at high resolution. The interval between these observations range from months to a decade in the quasar rest frame. While variability is common for intrinsic broad and mini-broad absorption lines, intrinsic narrow absorption lines have been found to be less likely to vary, though systematic studies with large, high quality datasets have been limited. The variability timescales are useful for deriving gas densities and thus the distances from the central engines. This is important in mapping the quasar surroundings, understanding the accretion disk wind mechanism, and assessing the effect the wind has on the galaxy surroundings. We report on the results of a systematic study of variability of NV NALs, exploiting the overlap of targets for observations in the archives of Keck and VLT, and discuss the consequences for interpretation of the origin of intrinsic narrow absorption lines.

  20. Multifunctionality is affected by interactions between green roof plant species, substrate depth, and substrate type.

    PubMed

    Dusza, Yann; Barot, Sébastien; Kraepiel, Yvan; Lata, Jean-Christophe; Abbadie, Luc; Raynaud, Xavier

    2017-04-01

    Green roofs provide ecosystem services through evapotranspiration and nutrient cycling that depend, among others, on plant species, substrate type, and substrate depth. However, no study has assessed thoroughly how interactions between these factors alter ecosystem functions and multifunctionality of green roofs. We simulated some green roof conditions in a pot experiment. We planted 20 plant species from 10 genera and five families (Asteraceae, Caryophyllaceae, Crassulaceae, Fabaceae, and Poaceae) on two substrate types (natural vs. artificial) and two substrate depths (10 cm vs. 30 cm). As indicators of major ecosystem functions, we measured aboveground and belowground biomasses, foliar nitrogen and carbon content, foliar transpiration, substrate water retention, and dissolved organic carbon and nitrates in leachates. Interactions between substrate type and depth strongly affected ecosystem functions. Biomass production was increased in the artificial substrate and deeper substrates, as was water retention in most cases. In contrast, dissolved organic carbon leaching was higher in the artificial substrates. Except for the Fabaceae species, nitrate leaching was reduced in deep, natural soils. The highest transpiration rates were associated with natural soils. All functions were modulated by plant families or species. Plant effects differed according to the observed function and the type and depth of the substrate. Fabaceae species grown on natural soils had the most noticeable patterns, allowing high biomass production and high water retention but also high nitrate leaching from deep pots. No single combination of factors enhanced simultaneously all studied ecosystem functions, highlighting that soil-plant interactions induce trade-offs between ecosystem functions. Substrate type and depth interactions are major drivers for green roof multifunctionality.

  1. Substrate binding ability of chemically inactivated pectinase for the substrate pectic acid.

    PubMed

    Chiba, Y; Kobayashi, M

    1995-07-01

    Pectinase (polygalacturonase) was purified from a commercial pectinase preparation from a mold. Substrate binding of pectinase was measured by centrifugal affinity chromatography using an immobilized substrate, pectic acid. Desorption of pectinase from the affinity matrix with the substrate pectin and pectic acid gave Kd values of 5.3 and 8.5 mg/ml, respectively. Chemical modification of pectinase by 1-ethyl-3-(3-dimethyl-aminopropyl)carbodiimide (EDC) and diethyl pyrocarbonate (DEP) caused a loss of most of the enzyme activity, but the substrate binding ability was not impaired. Thus, the pectinase preparation was digested with lysyl endopeptidase and the resulting peptides were treated with pectic acid-affinity gel. Three peptide fragments, which were recovered from the affinity column and sequenced, were identical to sequences in the second pectinase gene from Aspergillus niger. The first peptide contained 17 amino acids, Asp101-Ser117, and the second and third peptides corresponded to 18 amino acids of Asn152-Asp169. These results indicate that the inactivated pectinase retained substrate binding ability and would function as an acidic polysaccharide recognizing protein.

  2. Switchable narrow linewidth fiber laser with LP11 transverse mode output

    NASA Astrophysics Data System (ADS)

    Shen, Ya; Ren, Guobin; Yang, Yuguang; Yao, Shuzhi; Wu, Yue; Jiang, Youchao; Xu, Yao; Jin, Wenxing; Zhu, Bofeng; Jian, Shuisheng

    2018-01-01

    We experimentally demonstrate a switchable narrow linewidth single-longitudinal-mode (SLM) erbium-doped fiber (EDF) ring laser with LP11 transverse mode output. The laser is based on a mode selective all-fiber fused coupler which is composed of a single-mode fiber (SMF) and a two-mode fiber (TMF). By controlling the polarization state of the output light, the laser can provide narrow linewidth SLM output with LP11 transverse mode at two specific wavelengths, which correspond to two transmission peaks of the chirped moiré fiber grating (CMFBG). The 20 dB linewidth of the fiber laser for each wavelength is approximately 7.2 and 6.4 kHz.

  3. Carbon nanotubes on a substrate

    DOEpatents

    Gao, Yufei [Kennewick, WA; Liu, Jun [West Richland, WA

    2002-03-26

    The present invention includes carbon nanotubes whose hollow cores are 100% filled with conductive filler. The carbon nanotubes are in uniform arrays on a conductive substrate and are well-aligned and can be densely packed. The uniformity of the carbon nanotube arrays is indicated by the uniform length and diameter of the carbon nanotubes, both which vary from nanotube to nanotube on a given array by no more than about 5%. The alignment of the carbon nanotubes is indicated by the perpendicular growth of the nanotubes from the substrates which is achieved in part by the simultaneous growth of the conductive filler within the hollow core of the nanotube and the densely packed growth of the nanotubes. The present invention provides a densely packed carbon nanotube growth where each nanotube is in contact with at least one nearest-neighbor nanotube. The substrate is a conductive substrate coated with a growth catalyst, and the conductive filler can be single crystals of carbide formed by a solid state reaction between the substrate material and the growth catalyst. The present invention further provides a method for making the filled carbon nanotubes on the conductive substrates. The method includes the steps of depositing a growth catalyst onto the conductive substrate as a prepared substrate, creating a vacuum within a vessel which contains the prepared substrate, flowing H2/inert (e.g. Ar) gas within the vessel to increase and maintain the pressure within the vessel, increasing the temperature of the prepared substrate, and changing the H2/Ar gas to ethylene gas such that the ethylene gas flows within the vessel. Additionally, varying the density and separation of the catalyst particles on the conductive substrate can be used to control the diameter of the nanotubes.

  4. Genetic Epidemiology and Insights into Interactive Genetic and Environmental Effects in Autism Spectrum Disorders

    PubMed Central

    Kim, Young Shin; Leventhal, Bennett L.

    2014-01-01

    Understanding the pathogenesis of Neurodevelopmental Disorders (NDDs) has proven to be challenging. Using Autism Spectrum Disorder (ASD) as a paradigmatic NDD, this paper reviews the existing literature on the etiologic substrates of ASD and explores how genetic epidemiology approaches including gene-environment interactions (GxE) can play roles in identifying factors associated with ASD etiology. New genetic and bioinformatics strategies have yielded important clues to ASD genetic substrates. Next steps for understanding ASD pathogenesis require significant effort to focus on how genes and environment interact with one another in typical development and its perturbations. Along with larger sample sizes, future study designs should include sample ascertainment that is epidemiologic and population-based to capture the entire ASD spectrum with both categorical and dimensional phenotypic characterization, environmental measurement with accuracy, validity and biomarkers, statistical methods to address population stratification, multiple comparisons and GxE of rare variants, animal models to test hypotheses and, new methods to broaden the capacity to search for GxE, including genome-wide and environment-wide association studies, precise estimation of heritability using dense genetic markers and consideration of GxE both as the disease cause and a disease course modifier. While examination of GxE appears to be a daunting task, tremendous recent progress in gene discovery opens new horizons for advancing our understanding the role of GxE in the pathogenesis of, and ultimately identifying the causes, treatments and even prevention for ASD and other NDDs. PMID:25483344

  5. A spectrum fractal feature classification algorithm for agriculture crops with hyper spectrum image

    NASA Astrophysics Data System (ADS)

    Su, Junying

    2011-11-01

    A fractal dimension feature analysis method in spectrum domain for hyper spectrum image is proposed for agriculture crops classification. Firstly, a fractal dimension calculation algorithm in spectrum domain is presented together with the fast fractal dimension value calculation algorithm using the step measurement method. Secondly, the hyper spectrum image classification algorithm and flowchart is presented based on fractal dimension feature analysis in spectrum domain. Finally, the experiment result of the agricultural crops classification with FCL1 hyper spectrum image set with the proposed method and SAM (spectral angle mapper). The experiment results show it can obtain better classification result than the traditional SAM feature analysis which can fulfill use the spectrum information of hyper spectrum image to realize precision agricultural crops classification.

  6. M-shaped grating by nanoimprinting: a replicable, large-area, highly active plasmonic surface-enhanced Raman scattering substrate with nanogaps.

    PubMed

    Zhu, Zhendong; Bai, Benfeng; Duan, Huigao; Zhang, Haosu; Zhang, Mingqian; You, Oubo; Li, Qunqing; Tan, Qiaofeng; Wang, Jia; Fan, Shoushan; Jin, Guofan

    2014-04-24

    Plasmonic nanostructures separated by nanogaps enable strong electromagnetic-field confinement on the nanoscale for enhancing light-matter interactions, which are in great demand in many applications such as surface-enhanced Raman scattering (SERS). A simple M-shaped nanograting with narrow V-shaped grooves is proposed. Both theoretical and experimental studies reveal that the electromagnetic field on the surface of the M grating can be pronouncedly enhanced over that of a grating without such grooves, due to field localization in the nanogaps formed by the narrow V grooves. A technique based on room-temperature nanoimprinting lithography and anisotropic reactive-ion etching is developed to fabricate this device, which is cost-effective, reliable, and suitable for fabricating large-area nanostructures. As a demonstration of the potential application of this device, the M grating is used as a SERS substrate for probing Rhodamine 6G molecules. Experimentally, an average SERS enhancement factor as high as 5×10⁸ has been achieved, which verifies the greatly enhanced light-matter interaction on the surface of the M grating over that of traditional SERS surfaces. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  7. Maintainable substrate carrier for electroplating

    DOEpatents

    Chen, Chen-An [Milpitas, CA; Abas, Emmanuel Chua [Laguna, PH; Divino, Edmundo Anida [Cavite, PH; Ermita, Jake Randal G [Laguna, PH; Capulong, Jose Francisco S [Laguna, PH; Castillo, Arnold Villamor [Batangas, PH; Ma,; Xiaobing, Diana [Saratoga, CA

    2012-07-17

    One embodiment relates to a substrate carrier for use in electroplating a plurality of substrates. The carrier includes a non-conductive carrier body on which the substrates are placed and conductive lines embedded within the carrier body. A plurality of conductive clip attachment parts are attached in a permanent manner to the conductive lines embedded within the carrier body. A plurality of contact clips are attached in a removable manner to the clip attachment parts. The contact clips hold the substrates in place and conductively connecting the substrates with the conductive lines. Other embodiments, aspects and features are also disclosed.

  8. Maintainable substrate carrier for electroplating

    DOEpatents

    Chen, Chen-An; Abas, Emmanuel Chua; Divino, Edmundo Anida; Ermita, Jake Randal G.; Capulong, Jose Francisco S.; Castillo, Arnold Villamor; Ma, Diana Xiaobing

    2016-08-02

    One embodiment relates to a substrate carrier for use in electroplating a plurality of substrates. The carrier includes a non-conductive carrier body on which the substrates are placed and conductive lines embedded within the carrier body. A plurality of conductive clip attachment parts are attached in a permanent manner to the conductive lines embedded within the carrier body. A plurality of contact clips are attached in a removable manner to the clip attachment parts. The contact clips hold the substrates in place and conductively connecting the substrates with the conductive lines. Other embodiments, aspects and features are also disclosed.

  9. Narrowing the Gap in Outcomes for Vulnerable Groups: A Review of the Research Evidence

    ERIC Educational Resources Information Center

    Kendall, Sally; Straw, Suzanne; Jones, Megan; Springate, Iain; Grayson, Hilary

    2008-01-01

    This report presents findings from a review of the best evidence on narrowing the gap in outcomes across the five Every Child Matters (ECM) areas for vulnerable groups in the context of improving outcomes for all. The review was commissioned to prepare the ground for work on "Narrowing the Gap" with participating local authorities (LAs).…

  10. Broad photoelectron spectrum and lowered electron affinity due to hydrogen in ZnOH: A joint experimental and theoretical study

    NASA Astrophysics Data System (ADS)

    Iordanov, I.; Gunaratne, K. D. D.; Harmon, C. L.; Sofo, J. O.; Castleman, A. W.

    2012-06-01

    We report a combined experimental and theoretical photoelectron spectroscopy study of ZnOH-. We find that the electron binding energy spectrum of ZnOH- reveals a broad and featureless peak between 1.4 and 2.4 eV in energy. The vertical detachment energy (VDE) of ZnOH- is determined to be 1.78 eV, which is lower than the 2.08 eV VDE of ZnO-. Our theoretical calculations match the VDE of ZnOH- accurately, but we find that the broadness of the peak cannot be explained by rotational or vibrational state excitation. The broadness of this peak is in strong contrast to the narrow and easily understood first peak of the ZnO spectrum, which features a well-resolved vibrational progression that can be readily explained by calculating the Franck-Condon transition factors. This study provides spectroscopic evidence of the effect of hydrogen on diatomic ZnO.

  11. Broad photoelectron spectrum and lowered electron affinity due to hydrogen in ZnOH: a joint experimental and theoretical study.

    PubMed

    Iordanov, I; Gunaratne, K D D; Harmon, C L; Sofo, J O; Castleman, A W

    2012-06-07

    We report a combined experimental and theoretical photoelectron spectroscopy study of ZnOH(-). We find that the electron binding energy spectrum of ZnOH(-) reveals a broad and featureless peak between 1.4 and 2.4 eV in energy. The vertical detachment energy (VDE) of ZnOH(-) is determined to be 1.78 eV, which is lower than the 2.08 eV VDE of ZnO(-). Our theoretical calculations match the VDE of ZnOH(-) accurately, but we find that the broadness of the peak cannot be explained by rotational or vibrational state excitation. The broadness of this peak is in strong contrast to the narrow and easily understood first peak of the ZnO spectrum, which features a well-resolved vibrational progression that can be readily explained by calculating the Franck-Condon transition factors. This study provides spectroscopic evidence of the effect of hydrogen on diatomic ZnO.

  12. Hypersusceptibility to substrate analogs conferred by mutations in human immunodeficiency virus type 1 reverse transcriptase.

    PubMed

    Smith, Robert A; Anderson, Donovan J; Preston, Bradley D

    2006-07-01

    Human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) contains four structural motifs (A, B, C, and D) that are conserved in polymerases from diverse organisms. Motif B interacts with the incoming nucleotide, the template strand, and key active-site residues from other motifs, suggesting that motif B is an important determinant of substrate specificity. To examine the functional role of this region, we performed "random scanning mutagenesis" of 11 motif B residues and screened replication-competent mutants for altered substrate analog sensitivity in culture. Single amino acid replacements throughout the targeted region conferred resistance to lamivudine and/or hypersusceptibility to zidovudine (AZT). Substitutions at residue Q151 increased the sensitivity of HIV-1 to multiple nucleoside analogs, and a subset of these Q151 variants was also hypersusceptible to the pyrophosphate analog phosphonoformic acid (PFA). Other AZT-hypersusceptible mutants were resistant to PFA and are therefore phenotypically similar to PFA-resistant variants selected in vitro and in infected patients. Collectively, these data show that specific amino acid replacements in motif B confer broad-spectrum hypersusceptibility to substrate analog inhibitors. Our results suggest that motif B influences RT-deoxynucleoside triphosphate interactions at multiple steps in the catalytic cycle of polymerization.

  13. Quantum dots for GaAs-based surface emitting lasers at 1300 nm

    NASA Astrophysics Data System (ADS)

    Grundmann, M.; Ledentsov, N. N.; Hopfer, F.; Heinrichsdorff, F.; Guffarth, F.; Bimberg, D.; Ustinov, V. M.; Zhukov, A. E.; Kovsh, A. R.; Maximov, M. V.; Musikhin, Yu. G.; Alferov, Zh. I.; Lott, J. A.; Zhakharov, N. D.; Werner, P.

    InGaAs quantum dots (QD's) on GaAs substrate have been fabricated using metal-organic chemical vapor deposition (MOCVD) and molecular beam epitaxy (MBE) for the use in vertical cavity surface emitting laser diodes. Similar recombination spectra are obtained by employing the two different approaches of seeding and overgrowth with a quantum well. Despite the shift to larger wavelengths a large separation (=80 meV) between excited states is maintained. The introduction of such QD's into a vertical cavity leads to strong narrowing of the emission spectrum. Lasing from a 1300 nm InGaAs quantum dot VCSEL is reported.

  14. Six networks on a universal neuromorphic computing substrate.

    PubMed

    Pfeil, Thomas; Grübl, Andreas; Jeltsch, Sebastian; Müller, Eric; Müller, Paul; Petrovici, Mihai A; Schmuker, Michael; Brüderle, Daniel; Schemmel, Johannes; Meier, Karlheinz

    2013-01-01

    In this study, we present a highly configurable neuromorphic computing substrate and use it for emulating several types of neural networks. At the heart of this system lies a mixed-signal chip, with analog implementations of neurons and synapses and digital transmission of action potentials. Major advantages of this emulation device, which has been explicitly designed as a universal neural network emulator, are its inherent parallelism and high acceleration factor compared to conventional computers. Its configurability allows the realization of almost arbitrary network topologies and the use of widely varied neuronal and synaptic parameters. Fixed-pattern noise inherent to analog circuitry is reduced by calibration routines. An integrated development environment allows neuroscientists to operate the device without any prior knowledge of neuromorphic circuit design. As a showcase for the capabilities of the system, we describe the successful emulation of six different neural networks which cover a broad spectrum of both structure and functionality.

  15. Six Networks on a Universal Neuromorphic Computing Substrate

    PubMed Central

    Pfeil, Thomas; Grübl, Andreas; Jeltsch, Sebastian; Müller, Eric; Müller, Paul; Petrovici, Mihai A.; Schmuker, Michael; Brüderle, Daniel; Schemmel, Johannes; Meier, Karlheinz

    2013-01-01

    In this study, we present a highly configurable neuromorphic computing substrate and use it for emulating several types of neural networks. At the heart of this system lies a mixed-signal chip, with analog implementations of neurons and synapses and digital transmission of action potentials. Major advantages of this emulation device, which has been explicitly designed as a universal neural network emulator, are its inherent parallelism and high acceleration factor compared to conventional computers. Its configurability allows the realization of almost arbitrary network topologies and the use of widely varied neuronal and synaptic parameters. Fixed-pattern noise inherent to analog circuitry is reduced by calibration routines. An integrated development environment allows neuroscientists to operate the device without any prior knowledge of neuromorphic circuit design. As a showcase for the capabilities of the system, we describe the successful emulation of six different neural networks which cover a broad spectrum of both structure and functionality. PMID:23423583

  16. A narrow QRS tachycardia and cannon A waves: What is the mechanism?

    PubMed

    Ali, Hussam; Epicoco, Gianluca; De Ambroggi, Guido; Lupo, Pierpaolo; Foresti, Sara; Cappato, Riccardo

    2017-07-01

    Regular narrow QRS tachycardia, particularly if well-tolerated, is usually considered a "benign" arrhythmia of a supraventricular origin. This case concerns an 82-year-old male with ischemic heart disease who presented with recurrent episodes of a narrow QRS tachycardia that was initially diagnosed and treated as atrial tachyarrhythmia. However, careful physical examination and ECG analysis established the correct diagnosis, and the patient was managed appropriately. Remarkably, the observation of irregular cannon A waves, and Lewis lead recording, confirmed atrioventricular dissociation during tachycardia and indicated its underlying mechanism. © 2016 Wiley Periodicals, Inc.

  17. Narrow groove welding gas diffuser assembly and welding torch

    DOEpatents

    Rooney, Stephen J.

    2001-01-01

    A diffuser assembly is provided for narrow groove welding using an automatic gas tungsten arc welding torch. The diffuser assembly includes a manifold adapted for adjustable mounting on the welding torch which is received in a central opening in the manifold. Laterally extending manifold sections communicate with a shield gas inlet such that shield gas supplied to the inlet passes to gas passages of the manifold sections. First and second tapered diffusers are respectively connected to the manifold sections in fluid communication with the gas passages thereof. The diffusers extend downwardly along the torch electrode on opposite sides thereof so as to release shield gas along the length of the electrode and at the distal tip of the electrode. The diffusers are of a transverse width which is on the order of the thickness of the electrode so that the diffusers can, in use, be inserted into a narrow welding groove before and after the electrode in the direction of the weld operation.

  18. Period effects, cohort effects, and the narrowing gender wage gap.

    PubMed

    Campbell, Colin; Pearlman, Jessica

    2013-11-01

    Despite the abundance of sociological research on the gender wage gap, questions remain. In particular, the role of cohorts is under investigated. Using data from the Current Population Survey, we use age-period-cohort analysis to uniquely estimate age, period, and cohort effects on the gender wage gap. The narrowing of the gender wage gap that occurred between 1975 and 2009 is largely due to cohort effects. Since the mid-1990s, the gender wage gap has continued to close absent of period effects. While gains in female wages contributed to declines in the gender wage gap for cohorts born before 1950, for later cohorts the narrowing of the gender wage gap is primarily a result of declines in male wages. Copyright © 2013 Elsevier Inc. All rights reserved.

  19. Eta Carinae: Linelist for the Emission Spectrum of the Weigelt Blobs in the 1700-10400Angstrom Wavelength Region

    NASA Technical Reports Server (NTRS)

    Zethson, T.; Johansson, S.; Hartman, H.; Gull, T. R.

    2011-01-01

    Aims. We present line identifications in the 1700 to 10400A region for the Weigelt Blobs B and D, located 0.1 to 0.3" NNW of Eta Carinae. The aim of this work is to characterize the behavior of these luminous, dense gas condensations in response to the broad maximum and short minimum states of Eta Carinae during its 5.54-year spectroscopic period. Methods. The observations were carried out during March 1998, the minimum spectrum, and in February 1999, early maximum spectrum, with the Hubble Space Telescope/Space Telescope Imaging Spectrograph (HST/STIS) from 1640 to 10400A using the 52"x0.1" aperture centered on Eta Carinae at position angle -28 degrees. Extractions of the reduced spectrum centered on Weigelt B and D, 0.28: in length along the slit, were used to identify the narrow, nebular emission lines, measure their wavelengths and estimate their fluxes. Results. A linelist of 1500 lines is presented for the maximum and minimum states of combined Weigelt blobs B and D. The spectra are dominated by emission lines from the iron-group elements, but include lines from lighter elements. They include parity permitted and forbidden lines. A number of lines are fluorescent lines pumped by H Ly alpha. Other lines show anomalous excitation.

  20. Extended Narrow-Line Region in Seyfert Galaxies

    NASA Astrophysics Data System (ADS)

    Congiu, Enrico; Contini, Marcella.; Ciroi, Stefano; Cracco, Valentina; Di Mille, Francesco; Berton, Marco; Frezzato, Michele; La Mura, Giovanni; Rafanelli, Piero

    2017-10-01

    We present our recent results about the extended narrow-line region (ENLR) of two nearby Seyfert 2 galaxies (IC 5063 and NGC 7212) obtained by modelling the observed line profiles and spectra with composite models (photoionization+shocks) in the different regions surrounding the AGN. Then, we compare the Seyfert 2 ENLRs with the very extended one recently discovered in the narrow-line Seyfert 1 (NLS1) galaxy Mrk 783. We have found several evidences of interaction between the ISM of the galaxies and their radio jets, such as a) the contribution of shocks in ionizing the high velocity gas, b) the complex kinematics showed by the profile of the emission lines, c) the high fragmentation of matter, etc. The results suggest that the ENLR of IC 5063 have a hollow bi-conical shape, with one edge aligned to the galaxy disk, which may cause some kind of dependence on velocity of the ionization parameter. Regarding the Mrk 783 properties, it is found that the extension of the optical emission is almost twice the size of the radio one and it seems due to the AGN activity, although there is contamination by star formation around 12 arcsec from the nucleus. Diagnostic diagrams excluded the contribution of star formation in IC 5063 and NGC 7212, while the shock contribution was used to explain the spectra emitted by their high velocity gas.